GLOBE Goes GO with Mosquitoes

Science.gov (United States)

Boger, R. A.; Low, R.

2016-12-01

The GLOBE Mosquito Larvae protocol and a new citizen science initiative, GLOBE Observers (GO), were both launched in Summer 2016. While the GLOBE Mosquito Larvae Protocol and associated educational materials target K-16 student inquiry and research, the GO protocol version is simplified to enable citizen scientists of all ages from all walks of life to participate. GO allows citizen scientists to collect and submit environmental data through an easy-to-use smart phone app available for both Apple and Android mobile devices. GO mosquito asks for photos of larvae mosquito genus or species, location, and type of water source (e.g., container or pond) where the larvae were found. To initiate the new mosquito GLOBE/GO opportunities, workshops have been held in Barbuda, Thailand, West Indies, US Gulf Coast, New York City, and at the GLOBE Annual Meeting in Colorado. Through these venues, the protocols have been refined and a field campaign has been initiated so that GO and GLOBE citizen scientists (K-16 students and all others) can contribute data. Quality assurance measures are taken through the online training required to participate and the validation of identification by other citizen sciences and mosquito experts. Furthermore, initial research is underway to develop optical recognition software starting with the species that carry the Zika virus (Aedes aegypti and A. albopictus). With this launch, we plan to move forward by providing opportunities throughout the world to engage people in meaningful environmental and public health data collection and to promote citizen scientists to become agents of change in their communities.

Evolving Capabilities for Virtual Globes

Science.gov (United States)

Glennon, A.

2006-12-01

Though thin-client spatial visualization software like Google Earth and NASA World Wind enjoy widespread popularity, a common criticism is their general lack of analytical functionality. This concern, however, is rapidly being addressed; standard and advanced geographic information system (GIS) capabilities are being developed for virtual globes--though not centralized into a single implementation or software package. The innovation is mostly originating from the user community. Three such capabilities relevant to the earth science, education, and emergency management communities are modeling dynamic spatial phenomena, real-time data collection and visualization, and multi-input collaborative databases. Modeling dynamic spatial phenomena has been facilitated through joining virtual globe geometry definitions--like KML--to relational databases. Real-time data collection uses short scripts to transform user-contributed data into a format usable by virtual globe software. Similarly, collaborative data collection for virtual globes has become possible by dynamically referencing online, multi-person spreadsheets. Examples of these functions include mapping flows within a karst watershed, real-time disaster assessment and visualization, and a collaborative geyser eruption spatial decision support system. Virtual globe applications will continue to evolve further analytical capabilities, more temporal data handling, and from nano to intergalactic scales. This progression opens education and research avenues in all scientific disciplines.

The Globe gets a new skin

CERN Multimedia

Anaïs Schaeffer

2015-01-01

The Globe of Science and Innovation will be closed to the public from 4 May until the end of March 2016 for large-scale maintenance work. The renovation project, which is set to last about ten months, aims to overhaul the general building infrastructure and, above all, to replace a number of ageing components.   The Globe, during its assembly at CERN in 2004. Originally designed by Genevan architects Thomas Büchi and Hervé Dessimoz for the Swiss national “Expo 2002” exhibition in Neuchâtel, the Globe of Science and Innovation quickly became a symbol of CERN. In 2004, when it was relocated to its present site, the Globe acted as the venue hosting official delegations at the Laboratory’s 50th anniversary celebrations. Ten years on, thanks especially to the permanent exhibition Universe of Particles, the Globe has become THE venue for meetings and interactions between CERN and the general public, and is destined to continue in that ve...

Short-film Festival at the Globe

CERN Multimedia

2007-01-01

Get out your diaries and prepare to be star-struck as the Globe of Science and Innovation meets the silver screen! The CERN "Open Your Eyes Films" film-making club is organising a festival of short films entitled CinéGlobe from Thursday 8 to Saturday 10 November. On the Thursday and Friday, you’ll be able to watch 47 short films free of charge in the Globe of Science and Innovation at various times of the day. The short films to be screened come from 21 different countries and have been selected from among 1400 entrees! All film genres will be represented : comedy, drama, animation, documentaries, experimental films, etc. Members of the public will even be able to vote for their favourite film: the audience’s favourite will be awarded a "Coup de coeur" award. An awards ceremony to honour the films that have received most votes will be held on Friday evening in the Globe of Science and Innovation. The Golden CinéGlobe for bes...

The Globe laid bare

CERN Multimedia

Fortunati, Lucien

2015-01-01

If you’re at CERN at the moment, you will certainly have noticed the work under way on the Globe. The structure, which has been in pride of place opposite the Laboratory for over ten years, has never been so completely laid bare. But, as we explained in a previous article (see here), it is all for a good cause. The Globe is built entirely from wood and certain parts of it need to be replaced.

Teacher Preparation with GLOBE and NASA Assets

Science.gov (United States)

Czajkowski, K. P.; Templin, M.; Struble, J.; Mierzwiak, S.; Hedley, M. L.; Padgett, D.

2017-12-01

The GLOBE Program has been a working with teachers and students for over 20 years. Pre-service education students can be a target audience as well. Mission EARTH is a NASA funded project through the NASA Cooperative Agreement Notice (CAN) from the Science Mission Directorate. A goal of Mission EARTH is to improve student understanding of Earth System Science and to engage the next generation of scientists and global citizens. This presentation will discuss Weather and Climate courses offered at both the University of Toledo and Tennessee State University for pre-service education students. Students engaged in atmospheric observations through the GLOBE protocols and developed research projects to study El Nino. Undergraduate students helped K-12 students take GLOBE observations as well by partnering with in-service GLOBE teachers affiliated with these GLOBE partnerships.

The globe and orbit in Laron syndrome.

Science.gov (United States)

Kornreich, L; Konen, O; Lilos, P; Laron, Z

2011-09-01

Patients with LS have an inborn growth hormone resistance, resulting in failure to generate IGF-1. The purpose of this study was to evaluate the size of the eye and orbit in LS. We retrospectively reviewed the MR imaging of the brain in 9 patients with LS for the following parameters: axial diameter of the globe, interzygomatic distance, perpendicular distance from the interzygomatic line to margins of the globe, medial-to-lateral diameter of the orbit at the anterior orbital rim, distance from the anterior orbital rim to the anterior globe, maximal distance between the medial walls of the orbits, lateral orbital wall angle, lateral orbital wall length, and mediolateral thickness of the intraorbital fat in the most cranial image of the orbit. All measurements were made bilaterally. Twenty patients referred for MR imaging for unrelated reasons served as control subjects. Compared with the control group, the patients with LS had a significantly smaller maximal globe diameter and shallower but wider orbits due to a shorter lateral wall, a smaller medial distance between the orbits, and a larger angle of the orbit. The ratio between the most anterior orbital diameter and the globe was greater than that in controls. The position of the globe was more anterior in relation to the interzygomatic line. Shallow and wide orbits and small globes relative to orbital size are seen in LS and may be secondary to IGF-1 deficiency.

Children's drawings exhibited in the Globe

CERN Multimedia

Elizabeth Roe

2010-01-01

"Draw Me A Physicist" has been a success. Members of the public visiting the exhibition in the Globe of Science and Innovation have praised the scientific and creative balance the children of neighbouring France and the Canton of Geneva have obtained through their visit to CERN.   The Draw Me a Physicist exhibition in the Globe For a six-month period 9 to 11-year olds from the Pays de Gex, Meyrin, Satigny and Vernier have been able to enjoy a balance between science and art, through drawing and defining their interpretations of a physicist. In May, eight pairs of drawings from each participating class were selected by the schools to be displayed on the second floor of the Globe. Since the images have been put up, the viewers have enjoyed the contrast between the "before" pictures of vibrant Albert Einsteins to the "after" pictures of casual people sitting in an office. The large room in the Globe has been transformed from a hollow shell int...

Urban Utopias at the Globe

CERN Multimedia

2006-01-01

Since 19 May, the ground floor of the Globe has been housing a contemporary art exhibition. Meyrin's Contemporary Art Fund Committee has given six artists free rein to think up projects for the area surrounding the Globe, which is still a blank canvas. The exhibition entitled 'Urban Utopias', which explores the question 'How to experience the town?', consists of preparatory sketches and models of the works proposed by the artists. The projects on display include a metal ring symbolising the LHC accelerator, a statue consisting of pieces of broken wooden furniture, metal and bamboo, three metres in height, and even a projection of a computer-generated design for a ziggurat adjoining the Globe. Urban Utopias 19 May to 18 June, open Wednesday to Sunday from 2 p.m. to 6 p.m., Thursday until 9 p.m. Entrance free.

GLOBE-koolide õpilased assisteerivad NASA teadlasi / Imbi Henno

Index Scriptorium Estoniae

Henno, Imbi

2004-01-01

GLOBE (Global Learning and Observations to Benefit Environment) on õpilastele suunatud uurimuslikku ja praktilist tegevust pakkuv haridus- ja teadusprogramm. Õpilased teevad keskkonnavaatlusi ja mõõtmisi, saadavad oma tulemused interneti kaudu GLOBE'i andmebaasi ja kasutavad andmebaase koolitöös. Suvel toimus USA-s Boulderis GLOBE'i 10. tegevusaastale pühendatud konverents

Bilateral Traumatic Globe Luxation with Optic Nerve Transection

Directory of Open Access Journals (Sweden)

Levent Tok

2014-12-01

Full Text Available Purpose: The purpose of this study was to document clinical findings and management of a patient with bilateral globe luxation and optic nerve transection. Materials and Methods: A 25-year-old female patient was admitted to the emergency department with bilateral traumatic globe luxation following a motor vehicle accident. Results: Visual acuity testing showed no light perception. The right pupil was dilated and bilaterally did not react to light. The globes were bilaterally intact. A computed tomography scan revealed Le Fort type II fractures, bilateral optic nerve transection and disruption of all extraocular muscles. The globes of the patient were bilaterally reduced into the orbit. However, the patient developed phthisis bulbi in the right eye at month 3. Conclusion: Globe luxation presents a dramatic clinical picture, and may lead to the development of severe complications due to the concomitance of complete optic nerve dissection and multiple traumas. Even if the luxated globe is repositioned into the orbit, there is still an increased risk of the development of phthisis due to ischemia.

Bilateral Traumatic Globe Luxation with Optic Nerve Transection

Science.gov (United States)

Tok, Levent; Tok, Ozlem Yalcin; Argun, Tugba Cakmak; Yilmaz, Omer; Gunes, Alime; Unlu, Elif Nisa; Sezer, Sezgin; Ibisoglu, Seda; Argun, Mehmet

2014-01-01

Purpose The purpose of this study was to document clinical findings and management of a patient with bilateral globe luxation and optic nerve transection. Materials and Methods A 25-year-old female patient was admitted to the emergency department with bilateral traumatic globe luxation following a motor vehicle accident. Results Visual acuity testing showed no light perception. The right pupil was dilated and bilaterally did not react to light. The globes were bilaterally intact. A computed tomography scan revealed Le Fort type II fractures, bilateral optic nerve transection and disruption of all extraocular muscles. The globes of the patient were bilaterally reduced into the orbit. However, the patient developed phthisis bulbi in the right eye at month 3. Conclusion Globe luxation presents a dramatic clinical picture, and may lead to the development of severe complications due to the concomitance of complete optic nerve dissection and multiple traumas. Even if the luxated globe is repositioned into the orbit, there is still an increased risk of the development of phthisis due to ischemia. PMID:25606034

The Globe of Innovation takes shape

CERN Multimedia

2004-01-01

On 18 May, the central vortex of the CERN Globe of Innovation was put into place more than 22 metres above the ground. The central vortex of the Globe of Innovation is a crown measuring 6.15 metres in diameter and 4.5 meters in height. Having been lifted by a crane to a height of over 22 metres, the vortex is placed on a support structure which will be removed once the 36 arcs providing the building's structure have been secured in place. Resting some 22 metres above the ground, the central vortex of the Globe of Innovation is now ready to support the 36 wooden arcs which will provide the building's structure. Work to reassemble the former Palais de l'Equilibre, which was first erected in Neuchâtel for the EXPO.02 exhibition, began on 18 May. The sphere, measuring 40 metres in diameter, has now been renamed the Globe of Innovation. A detachment from the Swiss army is carrying out the work, which will be completed in time for the Organization's official fiftieth anniversary celebrations. The building will be...

Green light for a permanent exhibition in the Globe

CERN Multimedia

2008-01-01

A donation to the Foundation for the Globe of Science and Innovation by ROLEX S.A. marks the first step towards the planned expansion of the Globe’s infrastructure. The Globe: a CERN emblem.Visible from miles away by day and by night, the Globe, the wooden sphere offered to CERN by the Swiss Confederation in 2004, has become one of the symbols of the Organization. Since being opened to the public in September 2005, the Globe has served as a venue for lectures, exhibitions, press and VIP events and workshops for schoolchildren and as a stage for theatre performances on scientific themes. With a view to turning the Globe into a flagship venue for events for the general public, and for interactions between CERN and its public and private partners, two projects are planned for the near future. CERN is receiving support for these ventures from the Foundation for the Globe. Established at the end of 2007, the Foundation’s mission is to ...

Enlarged Heart

Science.gov (United States)

... rheumatic fever, a heart defect, infections (infectious endocarditis), connective tissue disorders, certain medications or radiation treatments for cancer, your heart may enlarge. Disease of the heart ...

Linking the GLOBE Program With NASA and NSF Large-Scale Experiments

Science.gov (United States)

Filmer, P. E.

2005-12-01

NASA and the NSF, the sponsoring Federal agencies for the GLOBE Program, are seeking the participation of science teams who are working at the cutting edge of Earth systems science in large integrated Earth systems science programs. Connecting the GLOBE concept and structure with NASA and NSF's leading Earth systems science programs will give GLOBE schools and students access to top scientists, and expose them to programs that have been designated as scientific priorities. Students, teachers, parents, and their communities will be able to see how scientists of many disciplines work together to learn about the Earth system. The GLOBE solicitation released by the NSF targets partnerships between GLOBE and NSF/NASA-funded integrated Earth systems science programs. This presentation will focus on the goals and requirements of the NSF solicitation. Proponents will be expected to provide ways for the GLOBE community to interact with a group of scientists from their science programs as part of a wider joint Earth systems science educational strategy (the sponsoring agencies', GLOBE's, and the proposing programs'). Teams proposing to this solicitation must demonstrate: - A focus on direct connections with major NSF Geosciences and/or Polar Programs and/or NASA Earth-Sun research programs that are related to Earth systems science; - A demonstrable benefit to GLOBE and to NSF Geosciences and/or Polar Programs or NASA Earth-Sun education goals (providing access to program researchers and data, working with GLOBE in setting up campaigns where possible, using tested GLOBE or non-GLOBE protocols to the greatest extent possible, actively participating in the wider GLOBE community including schools, among other goals); - An international component; - How the existing educational efforts of the large science program will coordinate with GLOBE; - An Earth systems science education focus, rather than a GLOBE protocol-support focus; - A rigorous evaluation and assessment component

A New Look for the Globe Gardens

CERN Multimedia

Katarina Anthony

2010-01-01

Designs to develop the grounds of the Globe of Science and Innovation have recently been unveiled. The plan is to extend the visitor activities on offer, transforming the area into a public arena for scientific exploration.   Design for the new Globe Gardens. © Jencks Squared and Groupe H. After months of conceptual development, plans to develop the site around the Globe are taking shape. The innovative designs were drawn up for CERN by a unique collaboration consisting of landscape architects Charles and Lily Jencks, and "Groupe H", a group of architects headed by Globe designer Hervé Dessimoz. They comprise new venues, covered walkways, a café and gift shop, a separate VIP entrance and a physics-inspired garden for visitors. The landscape itself becomes a feature – dramatically altered to create a cosmic garden formed by shaped mounds, ponds, and a natural amphitheatre for public events. “The new exhibition in the G...

Friday Programme for CineGlobe 2015

CERN Multimedia

Marcelloni De Oliveira, Claudia

2015-01-01

Workshops, apero with filmmakers and short-films inspired by science were the menu of the festival through the day. At night the CineGlobe DOME shown with the 360 degree projections shot-films; among them the avant-premiere of "Phantom of the Universe" - a movie that explains Dark Matter, directed by Joao Pequenao. Meanwhile at the Globe, the audience could enjoy the projections of the sequence of " The Invisible Photograph" .

Enlarged prostate

Science.gov (United States)

... for drugs that may make your symptoms worse : SAW PALMETTO Many herbs have been tried for treating an enlarged prostate. Many men use saw palmetto to ease symptoms. Some studies have shown that ...

Presenting CineGlobe Estival! | 6 - 10 July

CERN Multimedia

2016-01-01

Join CineGlobe under a projected starry sky for a film festival and games with a neuroscience twist.   The 6th edition of the CineGlobe International Film Festival at CERN will take place during the first week of July 2016 (on the Globe grounds at CERN, from Wednesday 6 to Friday 8 July) and then during the Nuit de la Science (at the Museum of the History of Science, on July 9 and 10). The festival will include an open-air cinema, film projections in the Globe of Science and Innovation at CERN, the interactive Emotional Circus (carnival-inspired games played with just the participant’s brainwaves) and a special sci-fi edition of the 48 Hour Film Project. The full program will target people of all ages with fun and informative activities such as children’s films in the Minima Cinema, and a workshop on the creation of a pinhole camera with an empty Tetra-Pak milk carton. Practical information: Entry is free. All films in English and French. Onsite food trucks at the G...

NATO Enlargement

National Research Council Canada - National Science Library

Gallis, Paul E

2003-01-01

This report provides a brief summary of the last round of NATO enlargement. The report analyzes the key military and political issues in the debate over seven prospective members named at NATO's Prague summit...

Enlarged adenoids

Science.gov (United States)

... lips Dry mouth Persistent runny nose or nasal congestion Enlarged adenoids may also cause sleep problems. A ... in the mouth or by inserting a flexible tube (called an endoscope) placed through the nose. Tests ...

Liver enlargement demonstrated by scintigraphy in rheumatoid arthritis

Energy Technology Data Exchange (ETDEWEB)

Tiger, L.H.; Gordon, M.H.; Ehrlich, G.E.; Shapiro, B.

1976-03-01

Scintigraphic scanning employing technetium-99m sulfur colloid was used to assess the size of the liver and spleen in 32 consecutive patients with rheumatoid arthritis. The data were correlated with clinical and laboratory assessment. Seven patients had enlarged livers, three enlarged spleens. An expected correlation of liver enlargement with Sjogren's syndrome did not materialize. Splenic enlargement and liver enlargement were discordant. Liver enlargement correlation best with elevations of rheumatoid factor as measured by latex fixation. As liver enlargement is not an appreciated feature of rheumatoid arthritis, these findings suggest that hepatomegaly need not necessarily imply adverse treatment results or the development of lymphoproliferative disorders.

Spontaneous globe luxation associated with chronic obstructive pulmonary disease

Directory of Open Access Journals (Sweden)

M Ashok Kumar

2012-01-01

Full Text Available Spontaneous globe luxation is a rarely reported condition which can lead to complications like optic neuropathy. Common causes are thyroid eye disease, shallow orbit and floppy eyelid syndrome. We report a case of spontaneous globe luxation with the onset and severity associated with chronic obstructive pulmonary disease (COPD. To our knowledge, this is the first case of spontaneous globe luxation associated with COPD.

Gingival Enlargement

Science.gov (United States)

... cover the crowns of the teeth causing periodontal (gum) disease (due to difficulty in keeping the teeth clean) ... localized and/or generalized gingival enlargement such as pregnancy, hormonal imbalances, and leukemia. To the right is ...

GLOBE-al Impact through Diversity Bootcamps and Student Research Symposia

Science.gov (United States)

Bourgeault, J.; Murphy, T.; Johnson, J.; Sparrow, E. B.; Czajkowski, K. P.; Herron, S.; Falcon, P.

2016-12-01

Inclusion, diversity, underrepresented groups, underserved populations...the key words and phrases that represent the students, we, as science education professionals, want to reach and encourage to enter the geoscience pipeline. Wanting to do this is one thing and having the skills to succeed is very different. It is also one that the GLOBE Program, an international science and education program, is working on as a community. GLOBE encourages students from around the world to participate in authentic scientific research of the Earth system. Students use scientific protocols to explore their local environments, compare their findings with other GLOBE schools both in the U.S. and in other participating countries, and then share their findings via the GLOBE.gov website. In the last year, two initiatives, six face-to-face Student Research Symposia and two diversity-focused GLOBE Partner Bootcamps, set the GLOBE community of Partners, teachers and students on the path to being able to address this challenge. This presentation will include the framework for the student research symposia, the barriers the leadership team faced when recruiting and getting students there and the lessons learned. Agendas for the GLOBE Partner Bootcamps will be shared to demonstrate how facilitators supplemented a standard GLOBE Partner workshop to model a more inclusive environment, along with future improvements to the format.

The Globe opens its doors to the public

CERN Multimedia

2005-01-01

The Globe of Science and Innovation has quickly become the most recognisable landmark on the CERN skyline. Since construction was completed last summer, the Globe's distinctive spherical shape has greeted and intrigued visitors and employees on arrival at CERN.

Globes and Teaching Aids Manufactured by Jan Felkl Company for the Polish Market

Directory of Open Access Journals (Sweden)

Malgorzata Taborska

2016-05-01

Full Text Available Jan Felkl company from Roztoky (Roztok near Prague manufactured globes in seventeen language versions, since 1861 also in Polish language. The company was active until 1952, but it ceased to manufacture Polish-language globes as early as in 1914. In the aftermath of the First World War, and with the development of printing business, the demand for Czech globes shrank. It is difficult to estimate the overall output of Polish- language globes manufactured by Felkl’s company throughout the 53 years it operated. From catalogues and the surviving globes we know that terrestrial globes in six sizes, folding globes in two sizes, celestial globes (probably in four sizes, as well as telluria, lunaria and planetaria were manufactured for the Polish market. It is difficult to decide how many editions of individual types of globes were issued. Polish names were compiled by Franciszek Waligórski (one globe and Mirosław Suchecki. Only 28 globes have survived to this day, including one celestial globe. Most of them are globes of an 8-inch diameter, approved by the Austrian ministries as teaching aids for schools. Nearly half of the surviving globes date from the years 1894–1914. Only ten items are in museums.

Occupational open globe injuries.

Science.gov (United States)

Vasu, U; Vasnaik, A; Battu, R R; Kurian, M; George, S

2001-03-01

Occupational ocular trauma is an important cause of acquired monocular blindness in a rapidly industrialising country like India. Knowledge of the epidemiology of occupational eye injuries is essential to formulate viable industrial safety measures. We retrospectively reviewed all patients with occupational open globe injuries between 1994 and 1998. We documented the circumstances of the injuries, their clinical findings and the use of appropriate protective eyewear at the time of the injury. The visual acuity 6 months after the injury was the final outcome measure. In this study period we examined 43 patients with open globe injuries sustained at the work place. Thirty-four (79.1%) patients were young males. The iron and steel industry accounted for 19 (44.2%) cases while 8 (18.6%) patients each were from the agricultural, mining and other small scale industrial sectors. At the time of the injury, 33 (76.7%) were not wearing the recommended protective eyewear and 6 (13.9%) were under the influence of alcohol. The injuries were mild in 6 (13.9%), moderate in 18 (41.9%) and severe in 19 (44.2%) patients. At the end of 6 months, 2 (4.7%) patients had a visual acuity of 6/12 or better, 4 (9.3%) had a visual acuity of 6/18 to 6/60 and 29 (67.4.%) had a vision of eyewear and alcohol-free environment at the work place is likely to reduce the incidence of severe occupational open globe injuries.

Tool or Toy? Virtual Globes in Landscape Planning

Directory of Open Access Journals (Sweden)

Stephen R. J. Sheppard

2011-10-01

Full Text Available Virtual globes, i.e., geobrowsers that integrate multi-scale and temporal data from various sources and are based on a globe metaphor, have developed into serious tools that practitioners and various stakeholders in landscape and community planning have started using. Although these tools originate from Geographic Information Systems (GIS, they have become a different, potentially interactive and public tool set, with their own specific limitations and new opportunities. Expectations regarding their utility as planning and community engagement tools are high, but are tempered by both technical limitations and ethical issues [1,2]. Two grassroots campaigns and a collaborative visioning process, the Kimberley Climate Adaptation Project case study (British Columbia, illustrate and broaden our understanding of the potential benefits and limitations associated with the use of virtual globes in participatory planning initiatives. Based on observations, questionnaires and in-depth interviews with stakeholders and community members using an interactive 3D model of regional climate change vulnerabilities, potential impacts, and possible adaptation and mitigation scenarios in Kimberley, the benefits and limitations of virtual globes as a tool for participatory landscape planning are discussed. The findings suggest that virtual globes can facilitate access to geospatial information, raise awareness, and provide a more representative virtual landscape than static visualizations. However, landscape is not equally representative at all scales, and not all types of users seem to benefit equally from the tool. The risks of misinterpretation can be managed by integrating the application and interpretation of virtual globes into face-to-face planning processes.

The Next Round of NATO Enlargement

National Research Council Canada - National Science Library

Simon, Jeffrey

2000-01-01

.... Political, geostrategic, and technical factors will frame policy options on enlargement though the shifting importance of these factors will likely influence any decision on enlarging the Alliance...

Exhibition at CERN's Globe of Science and Innovation

CERN Multimedia

Claudia Marcelloni

2006-01-01

Here we see pictures of displays at one of the exhibitions held at the Globe of Science and Innovation taken in September 2006. Located opposite the main CERN site, the Globe houses many public exhibitions throughout the year covering many topics from astronomy to particle physics.

The relationship of the globe to the orbital rim.

Science.gov (United States)

Eckstein, Lauren A; Shadpour, Joseph M; Menghani, Ravi; Goldberg, Robert A

2011-01-01

To present a novel method for accurately characterizing the position of the globe relative to the orbital rim. The appearance and function of the eyelids are dependent on the underlying orbital bony architecture and globe position; however, no comprehensive language to describe these complex 3-dimensional relationships exists. Three-dimensional orbital reconstructions were generated from computed tomographic scans of 15 Occidental and 12 Oriental orbits without orbital pathologic disease. Globe and orbital rim anatomy were identified and outlined. Reference points were measured along 2 independent axes: (1) the distance between a plane defined by the corneal apex and the sagittal projection of the orbital rim and (2) the distance between the circumference of the globe and the coronal projection of the orbital rim. For Occidental orbits, the mean (SD) elevation of the sagittal projection of the orbital rim relative to the anterior projection of the globe was 4.6 (4.2) mm superiorly, 5.9 (3.0) mm nasally, 12.6 (3.7) mm inferiorly, and 20.6 (2.6) mm laterally. The mean (SD) radial distance between the coronal projection of the orbital rim and the circumference of the globe was 3.7 (2.1) mm superiorly, 7.6 (1.8) mm nasally, 6.6 (2.2) mm inferiorly, and 4.6 (2.3) mm laterally. For Oriental orbits, the mean (SD) elevation of the sagittal projection of the orbital rim relative to the anterior projection of the globe was 5.0 (4.5) mm superiorly, 6.8 (4.1) mm nasally, 11.1 (4.3) mm inferiorly, and 17.5 (3.3) mm laterally. The mean (SD) radial distance between the coronal projection of the orbital rim and the circumference of the globe was 2.1 (1.2) mm superiorly, 8.2 (2.0) mm nasally, 6.5 (1.9) mm inferiorly, and 4.5 (1.7) mm laterally. Comparison of Occidental and Oriental orbital rim and globe configurations revealed quantitative and qualitative differences. In addition to differences in soft-tissue anatomy, bony architectural variations may contribute substantially to

Place-based Learning About Climate with Elementary GLOBE

Science.gov (United States)

Hatheway, B.; Gardiner, L. S.; Harte, T.; Stanitski, D.; Taylor, J.

2017-12-01

Place-based education - helping students make connections between themselves, their community, and their local environment - is an important tool to help young learners understand their regional climate and start to learn about climate and environmental change. Elementary GLOBE storybooks and learning activities allow opportunities for place-based education instructional strategies about climate. In particular, two modules in the Elementary GLOBE unit - Seasons and Climate - provide opportunities for students to explore their local climate and environment. The storybooks and activities also make connections to other parts of elementary curriculum, such as arts, geography, and math. Over the long term, place-based education can also encourage students to be stewards of their local environment. A strong sense of place may help students to see themselves as stakeholders in their community and its resilience. In places that are particularly vulnerable to the impacts of climate and environmental change and the economic, social, and environmental tradeoffs of community decisions, helping young students developing a sense of place and to see the connection between Earth science, local community, and their lives can have a lasting impact on how a community evolves for decades to come. Elementary GLOBE was designed to help elementary teachers (i.e., grades K-4) integrate Earth system science topics into their curriculum as they teach literacy skills to students. This suite of instructional materials includes seven modules. Each module contains a science-based storybook and learning activities that support the science content addressed in the storybooks. Elementary GLOBE modules feature air quality, climate, clouds, Earth system, seasons, soil, and water. New eBooks allow students to read stories on computers or tablets, with the option of listening to each story with an audio recording. A new Elementary GLOBE Teacher Implementation Guide, published in 2017, provides

Using the GLOBE Program To Enhance Classroom Teaching.

Science.gov (United States)

Ramey, Linda K.; Tomlin, James

The Wright State University Global Learning and Observations to Benefit the Environment (GLOBE) Franchise has developed a project to fill the need for direct, strong connections linking science, mathematics and technology to classroom curriculum and students' learning of integrated, relevant content. GLOBE is an international project that involves…

European Enlargement Across Rounds and Beyond Borders

DEFF Research Database (Denmark)

Enlargement has been an almost constant part of European integration history – going from an improvised exercise to the EU’s most developed foreign policy tool. However, neither the longevity nor the complexity of enlargement has been properly historicised. European Enlargement across Rounds...... and Beyond Borders offers three interdisciplinary, innovative, and indeed radical, new ways of understanding and analysing EC/EU enlargements: first, tracing Longue Durée developments; second, investigating enlargement Beyond the Road to Membership; and third, exploring the Entangled Exchanges and synergies...... scholars, should engage with it. This publication will be of key interest to scholars and students of modern European history and politics, the European integration process, EU studies, and more broadly multilateral international institutions, history, law and the social sciences....

Locally Motivated GLOBE Investigations - A Key to Success

Science.gov (United States)

Washburne, J. C.; Geery, W.

2003-12-01

The GLOBE program was set up to help students make a core set of environmental observations at or near their schools, report their data through the internet to share with other students and scientists, analyze their data both locally and globally, and use this knowledge to form a better understanding of their environment. While the GLOBE program has been successful promoting more meaningful data collection, many of the tools and much of the infrastructure available to schools to synthesize their observations are underused. Schools that integrate GLOBE protocols with locally motivated investigations are more likely to implement the higher-order analysis and synthesis components of the program. Indicators of a successful observational program are things like measurement persistence, high data quality, and regular data. Participation in community forums and student-based research projects are evidence of a successful integrated program. A locally motivated issue allows a school to mold their GLOBE investigations around a multi-faceted question that they have first-hand knowledge of, that is both relevant and engaging to their students, and that can be supported by local expertise. In contrast, many GLOBE investigations are designed around abstract, non-site specific, narrowly focused and externally analyzed questions that limit local involvement and motivation. The main focus of this presentation is a few case histories of successful local investigations that incorporated GLOBE soil and air temperature data-logger measurements. The main example is drawn from Mr. Geery's fifth grade class investigation of why temperature differences exist between a local river bottom area and the school, which is located several kilometers away and 100 meters higher.

Thymic enlargement in patients with hyperthyroidism

Energy Technology Data Exchange (ETDEWEB)

Myung, Jae Sung; Goo, Jin Mo; Im, Jung Gi [College of medicine and the Institute of Radiation Medicine, Seoul National University, Seoul (Korea, Republic of); Kim, Mi Young [Sejong General Hospital, Seoul (Korea, Republic of); Park, Yang Hee [National Police Hospital, Seoul (Korea, Republic of)

2000-08-01

To evaluate the radiologic findings and clinical feasibility of thymic enlargement in patients with hyperthyroidism. Seven patients with hyperthyroidism and anterior mediastinal bulging revealed by chest radiography were evaluated. The CT findings were analyzed with regard to the shape of the anterior mediastinal mass, surrounding infiltration, and enlargement of mediastinal lymph nodes. Whether or not tumor markers (alpha-fetoprotein, beta-human chorionic gonadotrophin, and chorionic embryonic antigen) showed increased levels was determined, and the size and thickness of the anterior mediastinal mass were measured and compared with previously described age-matched thymus data. In addition, changes in the thyroid gland were evaluated. In all seven patients, anterior mediastinal masses were bi-lobed, with no surrounding infiltration or enlarged mediastinal lymph node, and tumor marker levels showed no increase. The masses were therefore considered to be thymus. In six patients, the size of the thymus exceeded two upper standard deviations of mean value and in one patient, it was smaller than this. In three patients, PCNB (percutaneous needle biopsy) revealed normal thymic tissue and in two, follow-up chest PA demonstrated no interval change. CT showed that in three patients, the thyroid glands were diffusely enlarged. In patients with hyperthyroidism, an anterior mediastinal mass seen on chest radiographs was due to thymic enlargement. The recognition of CT findings of thymic enlargement in such patients may avoid unnecessary biopsy. (author)

A new mural for the Globe

CERN Multimedia

Laëtitia Pedroso

2010-01-01

A 53 metre long and 6 metre high mural has graced the ramp of the Globe since 21 June. Containing life-size photos of the CMS experiment and an event in the ATLAS detector, its visual impact cannot fail to rouse visitors' curiosity.   The new mural installed in the Globe Visitors ascending from the ground-floor to the first floor of the Globe are now greeted by a huge visual record of what's going on below ground at CERN and is no longer accessible on guided tours of the Laboratory. "The mural contains full-scale photos that give you a real feel of how the CMS detector is constructed and of the degree of precision of the particle tracks in the ATLAS event", explains Rolf Landua, Head of the Education Group, who came up with the project in conjunction with Bernard Pellequer. Several people were instrumental in bringing the project to life. The collage of 250 photographs of the CMS detector was retouched and assembled by Maximilien Brice, CERN's photographer, with the assistance o...

Globe of Natural Hazard - A new assessment tool for risk managers

Science.gov (United States)

Siebert, A. C.

2009-04-01

A large number of tropical cyclones and the earthquake in Sichuan made 2008 one of the most devastating years on record. Throughout the world, more than 220,000 people died as a result of natural catastrophes this year. Overall losses totaled some US 200bn (2007: US 82bn). Insured losses in 2008 rose to US 45bn, about 50% higher than in the previous year. Mainly driven by high losses from weather-related natural catastrophes, 2008 was - on the basis of figures adjusted for inflation - even the third most expensive year on record for the insurance industry, exceeded only by the hurricane year of 2005 and by 1995, the year of the Kobe earthquake. Munich Re, a worldwide operating reinsurance company, is a world leader in terms of investigating risks from natural hazards of all kinds. 2008 has again shown the insurance industry how important it is to analyse risks like natural hazards and climate change in all their facets and to manage the insurance business accordingly. An excellent example of the wealth of knowledge Munich Re has developed in natural hazard assessment is the DVD "Globe of Natural Hazards". It combines the geoscientific data and findings Munich Re has accumulated over a period of 35 years. First devised as a wall-map in 1978, the product has established itself as a standard work for the identification, exposure assessment and risk management of natural hazards. Over 80,000 copies of the CD-ROM version of 2000 have been provided to clients - a mark achieved by no other service product in Munich Re's history. Since the beginning of 2009, the fully updated fourth-generation version has been available. The bilingual DVD (German and English) shows natural hazards and climate effects at a glance: the global maps are presented on a 3D globe, underlaid with satellite images. The hazard complexes of hail, tornado and winter storms have been completely revised and flood incorporated as a new hazard. Users can intuitively home in on and enlarge any location on

EU Enlargement

DEFF Research Database (Denmark)

Pedersen, Peder J.; Pytlikova, Mariola

We look at migration flows from 8 Central and Eastern European Countries (CEECs) to 5 Nordic countries over the years 1985 - 2005 and we can exploit a natural experiment that arose from the fact that while Sweden opened its labour market from the day one of the 2004 EU enlargement, the other Nordic...... countries chose a transition period in relation to the "new" EU members. We employ a differences-in-differences estimator in our analysis. The results show that the estimated effect of the opening of Swedish labour market in 2004 on migration is insignificantly different from zero. Further, we...... are interested in the overall effect of the "EU entry" on migration. Therefore we look at migration flows from CEECs during the first round EU enlargement towards CEECs in 2004 and compare them with migration flows from Bulgaria and Romania. We again used a DD estimator in our analysis. The estimated effect...

Global Land One-kilometer Base Elevation (GLOBE) v.1

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — GLOBE is a project to develop the best available 30-arc-second (nominally 1 kilometer) global digital elevation data set. This version of GLOBE contains data from 11...

Penis-Enlargement Products: Do They Work?

Science.gov (United States)

... and surgeries. By Mayo Clinic Staff Ads for penis-enlargement products and procedures are everywhere. A plethora of ... your penis. Companies offer many types of nonsurgical penis-enlargement treatments, and often promote them with serious-looking ...

VRPI Temporal Progression of Closed Globe Injury from Blast Exposure

Science.gov (United States)

2015-09-01

significant increases in VEGF have been reported in many ocular disorders including diabetic retinopathy , diffuse macular edema, retinal vein...Open globe injury is often readily identifiable and typically undergoes urgent surgical repair. However, closed globe injury may not be detected ...including shrapnel or debris to the eye, is easily identified and rapidly treated. Closed globe trauma may not be detected right away, and little is

Airport Performance and Construction Enlargement Activities

Science.gov (United States)

Hanun, Y.; Setiawan, M. I.; Kurniasih, N.; Hasyim, C.; Ahmar, A. S.

2018-01-01

The evaluation of transportation infrastructure project should consider the contribution towards infrastructure growth. This research aims to analyze the effect of Construction enlargement activities towards airport performance. This research is correlation study. The population includes 148 airports in Indonesia. By using total sampling, there were 148 sample airports. The result shows that the construction enlargement activities variable has relatively strong relationship to Airport Performance variable, while the adjusted R Square score shows the increasing construction enlargement activities that affected by the other factors aside from airport performance.

Science Outreach in Virtual Globes; Best Practices

Science.gov (United States)

Treves, R. W.

2007-12-01

The popularity of projects such as 'Crisis in Darfur' and the IPY (International Polar Year) network link show the potential of using the rich functionality of Virtual Globes for science outreach purposes. However, the structure of outreach projects in Virtual Globes varies widely. Consider an analogy: If you pick up a science journal you immediately know where to find the contents page and what the title and cover story are meant to communicate. That is because journals have a well defined set of norms that they follow in terms of layout and design. Currently, science projects presented in virtual globes have, at best, weakly defined norms, there are little common structural elements beyond those imposed by the constraints of the virtual globe system. This is not a criticism of the science community, it is to be expected since norms take time to develop for any new technology. An example of the development of norms are pages on the web: when they first started appearing structure was unguided but over the last few years structural elements such as a left hand side navigation system and a bread crumb trail near the header have become common. In this paper I shall describe the developing norms of structure I have observed in one area of virtual globe development; Google Earth science outreach projects. These norms include text introductions, video introductions, use of folders and overlay presentation. I shall go on to examine how best to use these norms to build a clear and engaging outreach project and describe some cartographic best practices that we should also consider adopting as norms. I also will briefly explain why I think norms in science outreach aid creativity rather than limiting it despite the counter intuitive nature of this concept.

EU ENLARGEMENT AT A CROSSROADS

Directory of Open Access Journals (Sweden)

Andreea Cătălina Paul

2012-06-01

Full Text Available The present article aims to explore the general theme of the EU enlargement strategy in the new 2012 European context. Until now, the EU’s enlargement strategy has yielded impressive results. It succeeded in transforming ten central and eastern European countries from post-communism confusion into open-market, mature and effective systems of democratic governments, and even on the economic front, they have also made astonishing progress. It is no doubt that people in the new EU countries live better then before. In this context, the EU must continue the enlargement process to help stabilize the Balkan region that lie beyond its expanded eastern border. No one can deny that major issues concerning western Balkan countries’ accession are still on the table, and they even exert a geopolitical influence of sorts. This makes it all the more important to see stability and regional co-operation there are strategically vital. An all-out effort must now be made to complete the enlargement process and ensure there is no strategic vacuum. This article provides the framework of analyses for the EU problems and the challenges for the Balkans governments as for Brussels.

Stress -induced biosynthesis of dicaffeoylquinic acids in globe artichoke

NARCIS (Netherlands)

Moglia, A.; Lanteri, S.; Comino, C.; Acquadro, A.; Vos, de C.H.; Beekwilder, M.J.

2008-01-01

Leaf extracts from globe artichoke (Cynara cardunculus L. var. scolymus) have been widely used in medicine as hepatoprotectant and choleretic agents. Globe artichoke leaves represent a natural source of phenolic acids with dicaffeoylquinic acids, such as cynarin (1,3-dicaffeoylquinic acid), along

Hilar enlargement in respiratory syncytial virus pneumonia

International Nuclear Information System (INIS)

Odita, J.C.; Aghahowa, J.E.; Nwankwo, M.

1989-01-01

The clinical and radiographic features of ten children with hilar enlargement in association with proven Respiratory Syncytial Virus (RSV) infection are described. Hilar enlargement was seen in 10/35 children with RSV infection, and was invariably unilateral and right sided. It is recommended that RSV pneumonia be considered in children with unilateral hilar enlargement if tuberculosis has been excluded, and the onset of disease is rapid. (orig.)

Virtual Globes, where we were, are and will be

Science.gov (United States)

Dehn, J.; Webley, P. W.; Worden, A. K.

2016-12-01

Ten years ago, Google Earth was new, and the first "Virtual Globes" session was held at AGU. Only a few of us realized the potential of this technology at the time, but the idea quickly caught on. At that time a virtual globe came in two flavors, first a complex GIS system that was utterly impenetrable for the public, or a more accessible version with limited functionality and layers that was available on a desktop computer with a good internet connection. Google Earth's use of the Keyhole Markup Language opened the door for scientists and the public to share data and visualizations across disciplines and revolutionized how everyone uses geographic data. In the following 10 years, KML became more advanced, virtual globes moved to mobile and handheld platforms, and the Google Earth engine allowed for more complex data sharing among scientists. Virtual globe images went from a rare commodity to being everywhere in our lives, from weather forecasts, in our cars, on our smart-phones and shape how we receive and process data. This is a fantastic tool for education and with newer technologies can reach the the remote corners of the world and developing countries. New and emerging technologies allow for augmented reality to be merged with the globes, and for real-time data integration with sensors built into mobile devices or add-ons. This presentation will follow the history of virtual globes in the geosciences, show how robust technologies can be used in the field and classroom today, and make some suggestions for the future.

Unfolding Leonardo DA Vinci's Globe (ad 1504) to Reveal its Historical World Map

Science.gov (United States)

Verhoeven, G. J.; Missinne, S. J.

2017-08-01

This paper reports in detail on the image-based modelling and unwrapping approach used to create a two-dimensional projected map of an astonishing ostrich egg globe from AD 1504. This miniature egg globe is not only the oldest extant engraved globe, but it is also the oldest post-Columbian globe of the world and the first ever to depict Newfoundland and many other territories. The intention of digitally recording the surface geometry and colour of this unique artefact was to portray the original layout of the world map used by the Florentine Renaissance artist to make this globe. In addition, it was expected to substantiate iconographical details, which are hard to study at its scale of 1:80,000,000. The ostrich egg globe is the prototype of the Lenox Globe kept at the New York Public Library. The latter is very beneficial to examine how the egg globe looked like before being glued together at its equator. On the other hand, unfolding the map engraved in the ostrich egg halves enables a more detailed study of the remarkable details visible on both globes, since the engravings on the quasi-white egg surface are much easier to discern than those of the highly reflective red copper Lenox Globe. Finally, a detailed study of the unwrapped 3D surface is essential to learn more about the world vision of its creator and the incredible efforts that went into making this globe. Thanks to some particular pictographic details as well as the way in which the engravings are applied (by a left-handed person), the globe artist can be identified as Leonardo da Vinci.

"Big Science: the LHC in Pictures" in the Globe

CERN Multimedia

2008-01-01

An exhibition of spectacular photographs of the LHC and its experiments is about to open in the Globe. The LHC and its four experiments are not only huge in size but also uniquely beautiful, as the exhibition "Big Science: the LHC in Pictures" in the Globe of Science and Innovation will show. The exhibition features around thirty spectacular photographs measuring 4.5 metres high and 2.5 metres wide. These giant pictures reflecting the immense scale of the LHC and the mysteries of the Universe it is designed to uncover fill the Globe with shape and colour. The exhibition, which will open on 4 March, is divided into six different themes: CERN, the LHC and the four experiments ATLAS, LHCb, CMS and ALICE. Facts about all these subjects will be available at information points and in an explanatory booklet accompanying the exhibition (which visitors will be able to buy if they wish to take it home with them). Globe of Science and Innovatio...

And the winner of the Golden CinéGlobe is…

CERN Multimedia

Laëtitia Pedroso

2010-01-01

Three years after the first CinéGlobe festival, the CERN film club has just organised a second international festival of short films and science documentaries, attended by a host of film-makers and film fans alike. Six special prizes were awarded.   One of the Golden CinéGlobe awards The second Golden CinéGlobe award ceremony was held in the Globe on the evening of Saturday, 20 February. Now something of a magnet for local fans of short films and science documentaries, the CinéGlobe festival has become one of the most successful events organised by a CERN club. "Organising the festival has been a gratifying experience as many people have taken part in and enjoyed the event", says Quentin King, vice-chairman of the CERN film club, Open Your Eyes Films. "Time was our worst enemy. It took us a year to bring the project to fruition but we could have done with another year to refine some of the details". The 18 screenings...

Seeing Stars: A GLOBE at Night Campaign Update

Science.gov (United States)

Walker, Constance E.; Pompea, S. M.; Sparks, R. T.; Newhouse, M.

2012-01-01

The emphasis in the international citizen-science, star-hunting campaign, GLOBE at Night, is in bringing awareness to the public on issues of light pollution. Light pollution threatens not only observatory sites and our "right to starlight", but can affect energy consumption, wildlife and health. GLOBE at Night has successfully reached a few 100,000 citizen-scientists. What has done in the last year to contribute to its success? • To promote the campaign via popular social media, GLOBE at Night created Facebook and Twitter pages. • Videos have been created for 4 out of 8 Dark Skies Rangers activities. • Sky brightness measurements can be submitted in real time with smart phones or tablets using the new Web application at www.globeatnight.org/webapp/. The location, date and time register automatically. • As a proto-type, an adopt-a-street program had people in Tucson take measurements every mile for the length of the street. Grid measurements canvassed the town, allowing for comparisons of light levels over time. • The increase to 2 campaigns in 2011 re-enforces these studies. In 2012, the campaign will be offered 4 times for 10 days a month: January 14-23, February 12-21, March 13-22 and April 11-20. • A new Web application (www.globeatnight.org/mapapp/) allows for mapping GLOBE at Night data points within a specified distance around a city or area of choice. The resulting maps are bookmarkable and shareable. • NOAO and Arizona Game and Fish Department started a project with GLOBE at Night data and bat telemetry to examine a dark skies corridor in Tucson where endangered bats fly. While providing these updates to the GLOBE at Night program, the presentation will highlight the education and outreach value of the program's resources and outcomes, lessons learned, successes and pitfalls in communicating awareness with the public and attracting young people to study science.

GLOBE Cornerstones: Advancing Student Research Worldwide through Virtual and Regional Symposia

Science.gov (United States)

Bourgeault, J.; Malmberg, J. S.; Murphy, T.; Darche, S.; Ruscher, P.; Jabot, M.; Odell, M. R. L.; Kennedy, T.

2016-12-01

The GLOBE Program, an international science and education program, encourages students from around the world to participate in authentic scientific research of the Earth system. Students use scientific protocols to explore their local environments, compare their findings with other GLOBE schools both in the U.S. and in other participating countries, and then share their findings via the GLOBE.gov website. In order to facilitate this scientific communication, GLOBE held an international virtual science fair in 2016. The science fair included 105 research projects submitted from GLOBE students in various countries, 37 mentoring scientists, and 24 judges. Mentors and judges were members of the GLOBE International STEM Professionals Network and located around the world. On a national level, NSF funded six face-to-face U.S. regional student research symposia where 164 students presented 67 research projects to scientists for review. The 1.5 day events included student activities, teacher professional development, tours of NASA centers, and opportunities for students to engage with scientists to discover both traditional and non-traditional STEM career pathways. To support teachers, the leadership team offered and archived webinars on science practices; from field investigation basics to creating a poster and GLOBE partners provided guidance along the way. This presentation will include the framework for the regional and international science symposia , the scoring rubrics and evaluation, recruitment of judges and mentors, and lessons learned.

Eye globe abnormalities on MR and CT in adults: An anatomical approach

International Nuclear Information System (INIS)

Hallinan, James Thomas Patrick Decourcy; Pillay, Premilla; Koh, Lilian Hui; Goh, Kong Yong; Yu, Wai Yung

2016-01-01

Eye globe abnormalities can be readily detected on dedicated and non-dedicated CT and MR studies. A primary understanding of the globe anatomy is key to characterising both traumatic and non-traumatic globe abnormalities. The globe consists of three primary layers: the sclera (outer), uvea (middle), and retina (inner layer). The various pathological processes involving these layers are highlighted using case examples with fundoscopic correlation where appropriate. In the emergent setting, trauma can result in hemorrhage, retinal/choroidal detachment and globe rupture. Neoplasms and inflammatory/infective processes predominantly occur in the vascular middle layer. The radiologist has an important role in primary diagnosis contributing to appropriate ophthalmology referral, thereby preventing devastating consequences such as vision loss

Eye globe abnormalities on MR and CT in adults: An anatomical approach

Energy Technology Data Exchange (ETDEWEB)

Hallinan, James Thomas Patrick Decourcy; Pillay, Premilla [Dept. of Diagnostic Imaging, National University Health System, Singapore (Singapore); Koh, Lilian Hui [National Healthcare Group Eye Institute, Tan Tock Seng Hospital, Level 1, TTSH Medical Centre, Singapore (Singapore); Goh, Kong Yong [Yong Loo Lin School of Medicine, National University of Singapore, Singapore (Singapore); Yu, Wai Yung [Dept. of Neuroradiology, National Neuroscience Institute, Singapore (Singapore)

2016-09-15

Eye globe abnormalities can be readily detected on dedicated and non-dedicated CT and MR studies. A primary understanding of the globe anatomy is key to characterising both traumatic and non-traumatic globe abnormalities. The globe consists of three primary layers: the sclera (outer), uvea (middle), and retina (inner layer). The various pathological processes involving these layers are highlighted using case examples with fundoscopic correlation where appropriate. In the emergent setting, trauma can result in hemorrhage, retinal/choroidal detachment and globe rupture. Neoplasms and inflammatory/infective processes predominantly occur in the vascular middle layer. The radiologist has an important role in primary diagnosis contributing to appropriate ophthalmology referral, thereby preventing devastating consequences such as vision loss.

Eye Globe Abnormalities on MR and CT in Adults: An Anatomical Approach

Energy Technology Data Exchange (ETDEWEB)

Hallinan, James Thomas Patrick Decourcy; Pillay, Premilla [Department of Diagnostic Imaging, National University Health System, Singapore 119074 (Singapore); Koh, Lilian Hui Li [National Healthcare Group Eye Institute, Tan Tock Seng Hospital, Level 1, TTSH Medical Centre, Singapore 308433 (Singapore); Goh, Kong Yong [Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117597 (Singapore); Dr. Goh Eye Neuro-Ophthalmic and Low Vision Specialist, Mount Elizabeth Novena Specialist Centre, Singapore 329563 (Singapore); Yu, Wai-Yung [Department of Neuroradiology, National Neuroscience Institute, Singapore 308433 (Singapore)

2016-11-01

Eye globe abnormalities can be readily detected on dedicated and non-dedicated CT and MR studies. A primary understanding of the globe anatomy is key to characterising both traumatic and non-traumatic globe abnormalities. The globe consists of three primary layers: the sclera (outer), uvea (middle), and retina (inner layer). The various pathological processes involving these layers are highlighted using case examples with fundoscopic correlation where appropriate. In the emergent setting, trauma can result in hemorrhage, retinal/choroidal detachment and globe rupture. Neoplasms and inflammatory/infective processes predominantly occur in the vascular middle layer. The radiologist has an important role in primary diagnosis contributing to appropriate ophthalmology referral, thereby preventing devastating consequences such as vision loss.

Fetal adrenal gland enlargement - prenatal and postnatal management.

Science.gov (United States)

Lackova, Eliska; Cunderlik, Anton; Ticha, Lubica; Gabor, Maria

2017-11-01

The enlargement of suprarenal gland is related to preterm birth and the birth weight. The ultrasound measurement of fetal adrenal gland volume may identify women at risk for impending preterm birth. The aim of our study was to investigate the newborns in the region of western Slovakia followed up due to suprarenal gland enlargement. To set the ratio of prenatally diagnosed suprarenal gland enlargment, postnatal managment and treatment and interventions. The newborns with congenital adrenal hyperplasia were excluded. We have analyzed 6 years of medical records of all cases from the western Slovakia region of suprarenal gland enlargement encountered to 1st Pediatric Department, Children's University Hospital Bratislava Republic in the time period of January 2010 to Janurary 2016. The diagnosis of suprarenal gland enlargement was set by ultrasound examination performed on the 4th postnatal day as an overall screening test. Newborns with positive laboratory screening on congenital adrenal hyperplasia (CAH) were excluded from our study. We analyzed the origin of surarenal gland enlargement, gestation week on the due date, the birth weight and other comorbidities and genetic pathologies in newborns with the enlarged suprarenal glands. There were 6 newborns followed up due to suprarenal gland enlargement. All of the patients had diagnosed the adrenal haemorrhage. Adrenal lesions like adrenal cysts or neuroblastomas were not confirmed. All of the adrenal enlargements were benign with no need of other medical or surgical intervention. None of the newborn patients had other genetic abnormalities, mineral or hormonal imbalances, problems with arterial pressure or haemodynamic instability. All of the patients underwent at least 5 prenatal ultrasound tests and at least 2 postnatal ultrasound measurements. The avarage birth weight was 3030 grams (2700 grams - to 3750 grams). The avarage birth lenght was 50 cm (47 centimeter to 53 cm).The average gestation week (gw) on due date

GLOBE Aerosol Field Campaign - U.S. Pilot Study 2016

Science.gov (United States)

Pippin, Margaret; Marentette, Christina; Bujosa, Robert; Taylor, Jessica; Lewis, Preston

2016-01-01

During the spring of 2016, from April 4 - May 27, sixteen GLOBE schools participated in the GLOBE Aerosol Field Campaign - U.S. Pilot Study. Thirteen teachers from these schools had previously participated in the NASA LEARN program (Long-term Experience in Authentic Research with NASA) where they were GLOBE trained in Atmosphere protocols, and engaged in 1-3 years of research under the mentorship of NASA scientists. Each school was loaned two aerosol instruments for the Campaign duration, either 2 GLOBE sun photometers, 2 Calitoo sun photometers, or 1 of each. This allowed for students to make measurements side-by-side and in the case of the Calitoos, to compare AOT results immediately with each other for better consistency in data collection. Additionally, as part of the Field Campaign evaluation, multiple instruments allow for an assessment of the ease of use of each instrument for grade level of students, whether in middle school or high school. Before the Campaign, all GLOBE and Calitoo instruments were 'checked out' against an AERONET, then checked again upon return after the Campaign. By examining all data, before, during and after the Campaign, this gives an indication of instrument performance and proficiency obtained by the students. Support was provided to each teacher and their students at the level requested, via email, phone or video conferencing.

CinéGlobe invites you to participate in a poster design competition

CERN Multimedia

Neal David Hartman

2013-01-01

For its 2014 publicity campaign, CinéGlobe invites CERN people to participate in a poster design competition.  The entries are now on display on the Pas Perdus in the main building, and the CERNois are invited to vote for their favourites.    CinéGlobe is the international festival of short films inspired by science that takes place every two years at CERN, in the Globe of Science and Innovation. From 18 to 23 March 2014, CERN will host the fourth edition of the festival. The mission of the CinéGlobe Film Festival is to challenge the commonly perceived divisions between science and art by demonstrating that they are both essential to interpreting our world. Open to short film creators from around the world, the CinéGlobe festival is truly international, the first three editions having attracted more than 4,000 entries from more than 100 countries around the globe.  In addition to screening...

Improving predictive capabilities of environmental change with GLOBE data

Science.gov (United States)

Robin, Jessica Hill

This dissertation addresses two applications of Normalized Difference Vegetation Index (NDVI) essential for predicting environmental changes. The first study focuses on whether NDVI can improve model simulations of evapotranspiration for temperate Northern (>35°) regions. The second study focuses on whether NDVI can detect phenological changes in start of season (SOS) for high Northern (>60°) environments. The overall objectives of this research were to (1) develop a methodology for utilizing GLOBE data in NDVI research; and (2) provide a critical analysis of NDVI as a long-term monitoring tool for environmental change. GLOBE is an international partnership network of K-12 students, teachers, and scientists working together to study and understand the global environment. The first study utilized data collected by one GLOBE school in Greenville, Pennsylvania and the second utilized phenology observations made by GLOBE students in Alaska. Results from the first study showed NDVI could predict transpiration periods for environments like Greenville, Pennsylvania. In phenological terms, these environments have three distinct periods (QI, QII, and QIII). QI reflects onset of the growing season (mid March--mid May) when vegetation is greening up (NDVI 0.60). Results from the second study showed that a climate threshold of 153 +/- 22 growing degree days was a better predictor of SOS for Fairbanks than a NDVI threshold applied to temporal AVHRR and MODIS datasets. Accumulated growing degree days captured the interannual variability of SOS better than the NDVI threshold and most closely resembled actual SOS observations made by GLOBE students. Overall, biweekly composites and effects of clouds, snow, and conifers limit the ability of NDVI to monitor phenological changes in Alaska. Both studies did show that GLOBE data provides an important source of input and validation information for NDVI research.

Visualization on the Day Night Year Globe

International Nuclear Information System (INIS)

Božić, Mirjana; Vušković, Leposava; Popović, Svetozar; Popović, Jelena; Marković-Topalović, Tatjana

2016-01-01

The story about a properly oriented outdoor globe in the hands and minds of Eratosthenes, Jefferson, Milanković and science educators is presented. Having the same orientation in space as the Earth, the Day Night Year Globe (DING) shows in real time the pattern of illumination of the Earth’s surface and its diurnal and seasonal variations. It is an ideal object for the visualization of knowledge and increase in knowledge about: the form of the Earth, Earth’s rotation, Earth’s revolution around the Sun, the length of seasons, solstices, equinoxes, the longitude problem, the distribution of the Sun’s radiation over the Earth, the impact of this radiation on Earth’s climate, and how to use it efficiently. By attaching a movable vane to the poles, or adding pins around the equator to read time, DING becomes a spherical/globe-shaped sundial. So, the DING is simultaneously useful for teaching physics, geophysics, astronomy, use of solar energy and promoting an inquiry-based learning environment for students and the public. (paper)

A key component of the Globe arrives

CERN Multimedia

2003-01-01

The first component of the Palais de l'Equilibre arrived at CERN last week. Renamed the Globe of Innovation, this elegant wooden sphere will be inaugurated in October 2004. The convoy transporting the first component of the Palais de l'Equilibre, the keystone of the famous wooden globe, arrived at CERN on the night of 28th August in the middle of a violent storm and dramatic flashes of lightning. Erected in Neuchâtel last year for the EXPO.02 exhibition, the Palais de l'Equilibre was a gift to the Laboratory from the Swiss Confederation (see Bulletin 25/2003). The gift of the structure and 4 million Swiss francs, together with help from the Swiss army for the reassembly work, received the final approval of the Swiss Federal Council on 20th August 2003. Renamed the Globe of Innovation, the 27-metre-high sphere measuring 40 metres in diameter will house the Laboratory's new exhibition centre in 2005. The keystone, known as the "central vertex", is a crown measuring 6.5 m in diameter and 4.5 m high, located a...

Clinical characteristics and therapeutic effect of open globe injury

Directory of Open Access Journals (Sweden)

Mei-Lin Liu

2016-06-01

Full Text Available AIM: To analyze clinical characteristics and postoperative outcomes after open globe injury. METHODS: Demographic characteristics(age, gender, eye trauma, profession, cause of injury and injured part, as well as complications and prognosis were analyzed in 152 cases(152 eyesof open globe injury. RESULTS: Patients with open globe injury had an average age of 40.45±38.32 years old with a 5.9:1 male-to-female gender ratio. The left-to-right eye ratio was 1.27:1. Most patients were workers, farmers, or retired. The most common etiologies were scratches, boxing, and falls. Zone Ⅲ was the most commonly injured part. Iridoptosis or iris incarceration, retinal detachment, vitreal prolapse, hyphema or hypopyon, and vitreous hemorrhage were the most common complications. Visual acuity improved in 86 cases postoperatively but ophthalmectomy was still required in 25 eyes. CONCLUSION: Vision can be improved after surgery in open globe injury. However, patients are usually seriously injured and improvement is minimal, thereby resulting in a great loss to patients and society.

Luminosity declines in the Globe as it increases at the LHC

CERN Multimedia

Anaïs Schaeffer

2012-01-01

A few weeks ago, the skylight at the top of the Globe was fitted with "smart glass". The new glazing will allow the intensity of the light in the auditorium to be adjusted, thus solving the problem of sunlight reflecting on the giant screen during the day.   The Globe skylight while "off": the smart glass remains opaque. Inaugurated in 2004, the Globe of Science and Innovation has become one of the Organization's key landmarks. Housing the permanent exhibition "The Universe of Particles" (which recently received a silver design award, as reported in the last issue of the Bulletin) and a multimedia auditorium, the Globe hosts many events every year. "The Globe has rapidly become an important communication tool for CERN," enthuses Bernard Pellequer, who is in charge of event planning for the venue. "This is particularly true for the first floor, which is equipped with a giant screen. Unfortunately, we soon...

A web-system of virtual morphometric globes

Science.gov (United States)

Florinsky, Igor; Garov, Andrei; Karachevtseva, Irina

2017-04-01

Virtual globes — programs implementing interactive three-dimensional (3D) models of planets — are increasingly used in geo- and planetary sciences. We develop a web-system of virtual morphometric globes. As the initial data, we used the following global digital elevation models (DEMs): (1) a DEM of the Earth extracted from SRTM30_PLUS database; (2) a DEM of Mars extracted from the Mars Orbiter Laser Altimeter (MOLA) gridded data record archive; and (3) A DEM of the Moon extracted from the Lunar Orbiter Laser Altimeter (LOLA) gridded data record archive. From these DEMs, we derived global digital models of the following 16 local, nonlocal, and combined morphometric variables: horizontal curvature, vertical curvature, mean curvature, Gaussian curvature, minimal curvature, maximal curvature, unsphericity curvature, difference curvature, vertical excess curvature, horizontal excess curvature, ring curvature, accumulation curvature, catchment area, dispersive area, topographic index, and stream power index (definitions, formulae, and interpretations can be found elsewhere [1]). To calculate local morphometric variables, we applied a finite-difference method intended for spheroidal equal angular grids [1]. Digital models of a nonlocal and combined morphometric variables were derived by a method of Martz and de Jong adapted to spheroidal equal angular grids [1]. DEM processing was performed in the software LandLord [1]. The calculated morphometric models were integrated into the testing version of the system. The following main functions are implemented in the system: (1) selection of a celestial body; (2) selection of a morphometric variable; (3) 2D visualization of a calculated global morphometric model (a map in equirectangular projection); (4) 3D visualization of a calculated global morphometric model on the sphere surface (a globe by itself); (5) change of a globe scale (zooming); and (6) globe rotation by an arbitrary angle. The testing version of the system

Sodium valproate induced gingival enlargement with pre-existing chronic periodontitis

Directory of Open Access Journals (Sweden)

Vaibhavi Joshipura

2012-01-01

Full Text Available Gingival enlargement is a common clinical feature of gingival and periodontal diseases. Currently, more than 20 prescription medications are associated with gingival enlargement. Although the mechanisms of action may be different, the clinical and microscopic appearance of drug-induced gingival enlargement is similar with any drug. Gingival enlargement produces esthetic changes, and clinical symptoms including pain, tenderness, bleeding, speech disturbances, abnormal tooth movement, dental occlusion problems, enhancement of caries development and periodontal disorders. Sodium valproate is considered to produce gingival enlargement, but very rarely. This case report features sodium valproate induced gingival enlargement in a patient with pre-existing chronic periodontitis, who came to the Dental Department, Chinmaya Mission Hospital, Bangalore. The case is special as the patient did not develop the enlargement in spite of taking phenytoin for 1 year and developed enlargement with sodium valproate within 6 months.

Sodium valproate induced gingival enlargement with pre-existing chronic periodontitis.

Science.gov (United States)

Joshipura, Vaibhavi

2012-04-01

Gingival enlargement is a common clinical feature of gingival and periodontal diseases. Currently, more than 20 prescription medications are associated with gingival enlargement. Although the mechanisms of action may be different, the clinical and microscopic appearance of drug-induced gingival enlargement is similar with any drug. Gingival enlargement produces esthetic changes, and clinical symptoms including pain, tenderness, bleeding, speech disturbances, abnormal tooth movement, dental occlusion problems, enhancement of caries development and periodontal disorders. Sodium valproate is considered to produce gingival enlargement, but very rarely. This case report features sodium valproate induced gingival enlargement in a patient with pre-existing chronic periodontitis, who came to the Dental Department, Chinmaya Mission Hospital, Bangalore. The case is special as the patient did not develop the enlargement in spite of taking phenytoin for 1 year and developed enlargement with sodium valproate within 6 months.

Light Pollution Awareness through Globe at Night & IYL2015

Science.gov (United States)

Walker, Constance E.

2015-01-01

The International Astronomical Union (IAU) will be coordinating extensive activities to raise awareness of light pollution through running the Cosmic Light theme of the International Year of Light (IYL2015) and by partnering in particular with the popular Globe at Night program.Globe at Night (www.globeatnight.org) is an international campaign to raise public awareness of the impact of light pollution by having people measure night-sky brightness and submit observations in real-time with smart phone or later with a computer. In 2015, Globe at Night will run for 10-nights each month, an hour after sunset til before the Moon rises. Students can use the data to monitor levels of light pollution around the world, as well as understand light pollution's effects on energy consumption, plants, wildlife, human health and our ability to enjoy a starry night sky.Since its inception in 2006, more than 115,000 measurements from 115 countries have been reported. The last 9 years of data can be explored with Globe at Night's interactive world map or with the 'map app' to view a particular area. A spreadsheet of the data is downloadable from any year. One can compare Globe at Night data with a variety of other databases to see, for example, how light pollution affects the foraging habits of bats.To encourage public participation in Globe at Night during IYL2015, each month will target an area of the world that habitually contributes during that time. Special concerns for how light pollution affects that area and solutions will be featured on the Globe at Night website (www.globeatnight.org), through its Facebook page, in its newsletter or in the 365DaysofAstronomy.org podcasts.Twice during IYL there will be a global Flash Mob event, one on Super Pi Day (March 14, 2015) and a second in mid-September, where the public will be invited to take night-sky brightness measurements en masse. In April, the International Dark-Sky Week hosted by the International Dark-Sky Association will be

Enlarged facial pores: an update on treatments.

Science.gov (United States)

Dong, Joanna; Lanoue, Julien; Goldenberg, Gary

2016-07-01

Enlarged facial pores remain a common dermatologic and cosmetic concern from acne and rosacea, among other conditions, that is difficult to treat due to the multifactorial nature of their pathogenesis and negative impact on patients' quality of life. Enlarged facial pores are primarily treated through addressing associative factors, such as increased sebum production and cutaneous aging. We review the current treatment modalities for enlarged or dense facial pores, including topical retinoids, chemical peels, oral antiandrogens, and lasers and devices, with a focus on newer therapies.

UNFOLDING LEONARDO DA VINCI’S GLOBE (AD 1504 TO REVEAL ITS HISTORICAL WORLD MAP

Directory of Open Access Journals (Sweden)

G. J. Verhoeven

2017-08-01

Full Text Available This paper reports in detail on the image-based modelling and unwrapping approach used to create a two-dimensional projected map of an astonishing ostrich egg globe from AD 1504. This miniature egg globe is not only the oldest extant engraved globe, but it is also the oldest post-Columbian globe of the world and the first ever to depict Newfoundland and many other territories. The intention of digitally recording the surface geometry and colour of this unique artefact was to portray the original layout of the world map used by the Florentine Renaissance artist to make this globe. In addition, it was expected to substantiate iconographical details, which are hard to study at its scale of 1:80,000,000. The ostrich egg globe is the prototype of the Lenox Globe kept at the New York Public Library. The latter is very beneficial to examine how the egg globe looked like before being glued together at its equator. On the other hand, unfolding the map engraved in the ostrich egg halves enables a more detailed study of the remarkable details visible on both globes, since the engravings on the quasi-white egg surface are much easier to discern than those of the highly reflective red copper Lenox Globe. Finally, a detailed study of the unwrapped 3D surface is essential to learn more about the world vision of its creator and the incredible efforts that went into making this globe. Thanks to some particular pictographic details as well as the way in which the engravings are applied (by a left-handed person, the globe artist can be identified as Leonardo da Vinci.

Enlargement of the Baldone near-surface radioactive waste repository

International Nuclear Information System (INIS)

Dreimanis, A.

2007-01-01

A unified analysis of the enlargement of the Baldone near-surface radioactive waste (RW) repository RADONS considers the interplay of the existing engineering, safety and infrastructure premises, with the foreseen newly socio-technical features. This enlargement consists in construction of two additional RW disposal vaults and in building a long-term storage facility for spent sealed sources at the RADONS territory. Our approach is based on consecutive analysis of following basic elements: - the origin of enlargement - the RADONS safety analysis and a set of optimal socio-technical solutions of Salaspils research reactor decommissioning waste management; - the enlargement - a keystone of the national RW management concept, including the long-term approach; - the enlargement concept - the result of international co-operation and obligations; - arrangement optimization of new disposal and storage space; - environmental impact assessment for the repository enlargement - the update of socio-technical studies. The study of the public opinion revealed: negative attitude to repository enlargement is caused mainly due to missing information on radiation level and on the RADONS previous operations. These results indicate: basic measures to improve the public attitude to repository enlargement: the safety upgrade, public education and compensation mechanisms. A detailed stakeholders engagement and public education plan is elaborated. (author)

Twisted Acceleration-Enlarged Newton-Hooke Hopf Algebras

International Nuclear Information System (INIS)

Daszkiewicz, M.

2010-01-01

Ten Abelian twist deformations of acceleration-enlarged Newton-Hooke Hopf algebra are considered. The corresponding quantum space-times are derived as well. It is demonstrated that their contraction limit τ → ∞ leads to the new twisted acceleration-enlarged Galilei spaces. (author)

Teaching seismic methods using interactive 3D Earth globe

Science.gov (United States)

Weeraratne, D. S.; Rogers, D. B.

2011-12-01

Instructional techniques for study of seismology are greatly enhanced by three dimensional (3D) visualization. Seismic rays that pass through the Earth's interior are typically viewed in 2D slices of the Earth's interior. Here we present the use of a 3D Earth globe manufactured by Real World Globes. This globe displays a dry-erase high resolution glossy topography and bathymetry from the Smith and Sandwell data archives at its surface for interactive measurements and hands-on marking of many seismic observations such as earthquake locations, source-receiver distances, surface wave propagation, great circle paths, ocean circulation patterns, airplane trajectories, etc.. A new interactive feature (designed collaboratively with geoscientists) allows cut away and disassembly of sections of the exterior shell revealing a full cross section depicting the Earth's interior layers displayed to scale with a dry-erase work board. The interior panel spins to any azimuth and provides a depth measurement scale to allow exact measurements and marking of earthquake depths, true seismic ray path propagation, ray path bottoming depths, shadow zones, and diffraction patterns. A demo of this globe and example activities will be presented.

The "New Politics" of EU's Eastern Enlargement

DEFF Research Database (Denmark)

Zank, Wolfgang

The paper gives an overview of EU's eastern enlargement and draws some theoretical conclusions. In particular, it stresses the point that the EU member states in the process of enlargement have entered a phase of "new politics", characterised by multilateralism, conditionality, help and binding...

The Citizen-Scientist as Data Collector: GLOBE at Night, Part 2

Science.gov (United States)

Walker, C. E.; Pompea, S. M.; Ward, D.; Henderson, S.; Meymaris, K.; Gallagher, S.; Salisbury, D.

2006-12-01

An innovative program to realize light pollution education on two continents via Internet 2-based videoconferencing was begun 4 years ago by the National Optical Astronomy Observatory. Bilingual science teachers and their students in Arizona and Chile recorded the brightness of the night sky by matching its appearance toward the constellation Orion with one of 6 stellar maps of limiting magnitude. Students from both hemispheres would report their findings via videoconferences. In the last year the program has evolved in collaboration with UCAR and other partners into an international, user-friendly, web-based science event open to anyone in the world, known as GLOBE at Night. GLOBE at Night uses the same design to observe and record the visible stars toward Orion, as a means of measuring light pollution in a given location. The inaugural event occurred over 11 nights last March, when 18,000 citizen- scientists made over 4,500 observations from 96 countries. Analysis of the GLOBE at Night data set found that the brighter skies corresponded to areas with higher population density, and that most observations were taken in a location with some light pollution. The data also tended to confirm that satellite data is reliable in assessing light pollution. This session will describe our program to incorporate more technology into the GLOBE at Night program. Citizen-scientists will use sky quality meters (visible light photometers), calibrated digital photography, and GPS as a means to measure and map more accurately the brightness of the sky at selected urban and rural sites. This extension of the program is designed to aid further in teaching about the impact of artificial lighting on local environments and the ongoing loss of a dark night sky as a natural resource. We will also describe how detailed maps of selected urban areas can be used to assess lighting design, safety considerations and energy usage. Given the widespread interest in the inaugural GLOBE at Night

Implementing GLOBE in the New York City Metropolitan Area: Trials, Errors, and Successes

Science.gov (United States)

Ludman, A.; Schmidt, P.; Borman, G.

2003-12-01

The Queens College GLOBE NY Metro Partnership was created to introduce GLOBE to more than 1.5 million students in southern NY State and provide continuing support for their teachers. In our first 18 months, we have trained 185 teachers from 82 schools and will triple these numbers this year. Teachers and administrators are attracted to GLOBE by its scientific rigor, the authentic research it offers students, and its fit with NYS standards. They are also eager to interact with our science faculty. Early difficulties included problems with the "standard" 5-day GLOBE training format and misconceptions that protocols are not suitable for urban settings and that preparing for the NYS Regents exams leaves no room for GLOBE. We held information meetings for school districts and for Queens high schools before our first workshop. These identified the most committed schools, energetic teachers, and potential implementation problems. Creative participants at these meetings countered the misconceptions and suggested solutions to the problems better than any outsider could, and generated an atmosphere leading to nearly 100% recruitment. The following stratagems have worked well: a close working relationship with the NYC Dept of Education, BOCES, and other environmental educators; affiliations with government agencies and community environmental groups; two bribes (giving a GLOBE instrument kit and GPS unit to each school that we train and awarding graduate or professional development credits for GLOBE training); a user-friendly training format (an initial 3-day workshop followed by two optional days for hydrology and land use); lending seldom-used items (e.g. soil auger) when needed; building a sense of GLOBE community with a graduation "ceremony", local website (www.qc.edu/qcglobe) and newsletter, phone and email helplines, and annual pedagogy and student research conferences. We also urge that three teachers be trained from each school in order to build local GLOBE support

CHANGING FROM WITHIN? THE INTRA-ORGANIZATIONAL DYNAMICS OF EU ENLARGEMENT

Directory of Open Access Journals (Sweden)

Velibor JAKOVLESKI

2015-12-01

Full Text Available This paper opens up the black box of enlargement, focusing on how the intra-organizational relationships among the Council of the European Union, the European Commission, and the European Parliament affect the process of enlargement. Formally speaking, enlargement is an intergovernmental process, suggesting that member states are firmly in control of its outcomes. However, the EU’s supranational actors, specifically the European Parliament and European Commission also attempt to influence enlargement at various stages. I posit that the process of enlargement to the Western Balkans has evolved, influenced by changing constraints which are operating on the aforementioned actors. The added value of this work is in disaggregating the enlargement process based on its institutionalized relationships in both a vertical and horizontal dimension. It provides a supply-side argument for how enlargement policy has evolved from within the EU, rather than simply as a function of external factors.

Enlargement of filtration with finance in view

CERN Document Server

Aksamit, Anna

2017-01-01

This volume presents classical results of the theory of enlargement of filtration. The focus is on the behavior of martingales with respect to the enlarged filtration and related objects. The study is conducted in various contexts including immersion, progressive enlargement with a random time and initial enlargement with a random variable.  The aim of this book is to collect the main mathematical results (with proofs) previously spread among numerous papers, great part of which is only available in French. Many examples and applications to finance, in particular to credit risk modelling and the study of asymmetric information, are provided to illustrate the theory. A detailed summary of further connections and applications is given in bibliographic notes which enables to deepen study of the topic.  This book fills a gap in the literature and serves as a guide for graduate students and researchers interested in the role of information in financial mathematics and in econometric science. A basic knowledge of...

Eratosthenes' teachings with a globe in a school yard

International Nuclear Information System (INIS)

Božić, Mirjana; Ducloy, Martial

2008-01-01

A globe, in a school or university yard, which simulates the Earth's orientation in space, could be a very useful and helpful device for teaching physics, geometry, astronomy and the history of science. It would be very useful for science education to utilize the forthcoming International Year of the Planet Earth 2008 and the International Year of Astronomy 2009 by installing globes in many school and university courtyards

Globes, Maps, Photographs: Geographic Tools.

Science.gov (United States)

McDermott, Paul D.; And Others

This compilation of reprinted articles that originally appeared in the Journal of Geography from September 1969 through the May 1970 issues, is intended to help teachers use globes, maps, and photographs with skill and understanding. The articles were designed with several objectives in mind: 1) to provide information regarding the design,…

Enlarged prostate - after care

Science.gov (United States)

... page: //medlineplus.gov/ency/patientinstructions/000398.htm Enlarged prostate - after care To use the sharing features on this page, please enable JavaScript. The prostate is a gland that produces the fluid that ...

Dark Skies Awareness through the GLOBE at Night Citizen-Science Campaign

Science.gov (United States)

Walker, C. E.

2011-10-01

The emphasis in the international citizen-science, star-hunting campaign, GLOBE at Night, is in bringing awareness to the public on issues of light pollution. Light pollution threatens not only observatory sites and our "right to starlight", but can affect energy consumption, wildlife and health. GLOBE at Night has successfully reached a few hundred thousand citizen-scientists during the annual 2-week campaign over the past 6 years. Provided is an overview, update and discussion of what steps can be taken to improve programs like GLOBE at Night.

EYE TRAUMA. OPEN GLOBE INJURY MANAGEMENT

Directory of Open Access Journals (Sweden)

Mojca Globočnik Petrovič

2004-05-01

Full Text Available Background. Ocular trauma is important cause of blindness. Birmingham Eye Trauma Terminology allows us to use a standardized eye injury terminology which permits an unambigous interpretation. The Eye Injury Registry enables the analysis of medical, epidemyologic and social data.The most frequent ocular injury ocular contusion has a relatively good prognosis. An adequate primary ocular repair and correct timing of pars plana vitrectomy are very important in open globe injury management. There still exist some controversial issues concerning the role of posterior segment surgery in open globe injuries. These include timing of surgery, prophylactic scleral buckle placement and a proper use of systemic and intravitreal antibiotics.Conclusions. With adequate primary ocular repair, the use of systemic, intravitreal antibiotics, scleral buckling and proper timing for pars plana vitrectomy the prognosis for ocular trauma cases can be better.

Sodium valproate induced gingival enlargement with pre-existing chronic periodontitis

OpenAIRE

Joshipura, Vaibhavi

2012-01-01

Gingival enlargement is a common clinical feature of gingival and periodontal diseases. Currently, more than 20 prescription medications are associated with gingival enlargement. Although the mechanisms of action may be different, the clinical and microscopic appearance of drug-induced gingival enlargement is similar with any drug. Gingival enlargement produces esthetic changes, and clinical symptoms including pain, tenderness, bleeding, speech disturbances, abnormal tooth movement, dental oc...

Genetic mapping and annotation of genomic microsatellites isolated from globe artichoke

NARCIS (Netherlands)

Acquadro, A.; Lanteri, S.; Scaglione, D.; Arens, P.F.P.; Vosman, B.; Portis, E.

2009-01-01

Cynara cardunculus includes three taxa, the globe artichoke (subsp. scolymus L. Hegi), the cultivated cardoon (var. altilis) and their progenitor, the wild cardoon (var. sylvestris). Globe artichoke is an important component of the Mediterranean rural economy, but its improvement through breeding

The Globe reopens its doors

CERN Multimedia

CERN Bulletin

2016-01-01

After a year of work, the newly renovated Globe of Science and Innovation will open its doors again at 10 a.m. on Tuesday, 19 April. The “Universe of Particles” exhibition has been updated and will be open to the public, free of charge, from 10 a.m. to 5 p.m., Monday to Saturday (except during official CERN closures). The Globe’s programme of lectures and events for the general public will restart at the end of April. What’s on at the Globe in April and May: - 28 April at 6.30 p.m.: Theatre – “Curie_Meitner_Lamarr_indivisible”, a play that pays tribute to the lives of three exceptional women in the field of science and technology (in English). Reservations: http://indico.cern.ch/e/cmli - 10 May at 8.30 p.m.: Lecture – “Le modèle du CERN et les grands défis mondiaux” (“The CERN model and the key global challenges”) by Michel Spiro (in French with simultaneous ...

Determining Light Pollution of the Global Sky: GLOBE at Night

Science.gov (United States)

Henderson, S.; Meymaris, K.; Ward, D.; Walker, C.; Russell, R.; Pompea, S.; Salisbury, D.

2006-05-01

GLOBE at Night is an international science event designed to observe and record the visible stars as a means of measuring light pollution in a given location. Increased and robust understanding of our environment requires learning opportunities that take place outside of the conventional K-12 classroom and beyond the confines of the school day. This hands-on learning activity extended the traditional classroom and school day last March with a week of nighttime sky observations involving teachers, students and their families. The quality of the night sky for stellar observations is impacted by several factors including human activities. By observing cloud cover and locating specific constellations in the sky, students from around the world learned how the lights in their community contribute to light pollution, exploring the relationship between science, technology and their society. Students learned that light pollution impacts more than just the visibility of stars at night. Lights at night impact both the biology and ecology of many species in our environment. Students were able to participate in this global scientific campaign by submitting their observations through an online database, allowing for authentic worldwide research and analysis by participating scientists. Students and their families learned how latitude and longitude coordinates provide a location system to map and analyze the observation data submitted from around the globe. The collected data is available online for use by students, teachers and scientists worldwide to assess how the quality of the night sky varies around the world. This session will share how students and scientists across the globe can explore and analyze the results of this exciting campaign. GLOBE at Night is a collaborative effort sponsored by The GLOBE Program, the National Optical Astronomy Observatory (NOAO), Centro de Apoyo a la Didactica de la Astronomia (CADIAS), Windows to the Universe, and ESRI. The GLOBE Program is

The Citizen-Scientist as Data Collector: GLOBE at Night, Part 1

Science.gov (United States)

Ward, D. L.; Henderson, S.; Meymaris, K.; Walker, C.; Pompea, S. M.; Gallagher, S.; Salisbury, D.

2006-12-01

GLOBE at Night is an international science event designed to observe and record the visible stars as a means of measuring light pollution in a given location. Increased and robust understanding of our environment requires learning opportunities that take place outside of the conventional K-12 classroom and beyond the confines of the school day. This hands-on learning activity extended the traditional classroom and school day through 11 nights last March, when 18,000 citizen-scientists made over 4,500 observations from 96 countries. Utilizing the international networking capabilities of The GLOBE Program, GLOBE at Night was designed to make data collection and input user-friendly. Citizen-scientists were able to participate in this global scientific campaign by submitting their observations through an online database, allowing for authentic worldwide research and analysis by participating scientists. The data collected is available online in a variety of formats for use by students, teachers and scientists worldwide to assess how the quality of the night sky varies around the world. Using the online analysis tools provided by ESRI, participants were able to compare the observed data with population density and nighttime lighting datasets (DMSP Earth at Night). This comparison allowed correlations between observed data patterns and commonly used indices of population density and energy usage. This session will share our results and demonstrate how students and scientists across the globe can explore and analyze the results of this exciting campaign. We will discuss how the project team planned and executed the project in such a way that non-astronomers were able to make valid and useful contributions. We will also discuss lessons learned and best practices based on the 2006 campaign. GLOBE at Night is a collaborative effort sponsored by The GLOBE Program, the National Optical Astronomy Observatory (NOAO), Centro de Apoyo a la Didactica de la Astronomia (CADIAS

Rib enlargement in premature infants with bronchopulmonary dysplasia

Energy Technology Data Exchange (ETDEWEB)

Yoon, Hye Kyung; Han, Kim Bokyung; Chang, Yun Sil; Choo, In Wook [Samsung Medical Center, School of Medicine, Sungkyunkwan University, Seoul (Korea, Republic of); Kim, Kyeong Ah [Anyang General Hospital, Anyang (Korea, Republic of)

2000-04-01

The purpose of this study is to describe the rib changes seen in patients with brochopulmonary dysplasia (BPD). Serial chest radiographs of nine premature infants with BPD who showed diffuse rib enlargement were reviewed for hyperinflation, which was compared with the observed degree of rib enlargement. Vibrator chest physiotherapy was performed in all cases, and five infants underwent conventional ventilation plus high frequency oscillatory ventilation therapy. Their calcium level was normal whereas alkaline phosphatase and phosphate levels were high. In all infants except one, liver enzyme levels were normal. For the treatment of patent ductus arteriosus, infection, and BPD, medications including indomethacin, antibiotics, and dexamethasone were administered. Vitamin D was given to all patients with total parenteral nutrition. Rib enlargement was found to be severe (n=3D4), moderate (n=3D3), or mild (n=3D2) with undulating margins or posterior tapering (n=3D2). Hyperinflation was noted in eight patients, in seven of whom it was moderate to severe. Among these seven, rib enlargement was severe (n=3D2), moderate (n=3D3), or mild (n=3D2). In one infant with mild hyperinflation, rib enlargement was severe. Bilateral irregular infiltrates and atelectases were noted in all patients. In BPD patients, rib enlargement may be seen. In order to differentiate this process from systemic bone disease or bony dysplasia, an awareness of the rib changes occurring in patients with BPD may be important. (author)

Rib enlargement in premature infants with bronchopulmonary dysplasia

International Nuclear Information System (INIS)

Yoon, Hye Kyung; Han, Kim Bokyung; Chang, Yun Sil; Choo, In Wook; Kim, Kyeong Ah

2000-01-01

The purpose of this study is to describe the rib changes seen in patients with brochopulmonary dysplasia (BPD). Serial chest radiographs of nine premature infants with BPD who showed diffuse rib enlargement were reviewed for hyperinflation, which was compared with the observed degree of rib enlargement. Vibrator chest physiotherapy was performed in all cases, and five infants underwent conventional ventilation plus high frequency oscillatory ventilation therapy. Their calcium level was normal whereas alkaline phosphatase and phosphate levels were high. In all infants except one, liver enzyme levels were normal. For the treatment of patent ductus arteriosus, infection, and BPD, medications including indomethacin, antibiotics, and dexamethasone were administered. Vitamin D was given to all patients with total parenteral nutrition. Rib enlargement was found to be severe (n=3D4), moderate (n=3D3), or mild (n=3D2) with undulating margins or posterior tapering (n=3D2). Hyperinflation was noted in eight patients, in seven of whom it was moderate to severe. Among these seven, rib enlargement was severe (n=3D2), moderate (n=3D3), or mild (n=3D2). In one infant with mild hyperinflation, rib enlargement was severe. Bilateral irregular infiltrates and atelectases were noted in all patients. In BPD patients, rib enlargement may be seen. In order to differentiate this process from systemic bone disease or bony dysplasia, an awareness of the rib changes occurring in patients with BPD may be important. (author)

A Review of Global Learning & Observations to Benefit the Environment (GLOBE)

Science.gov (United States)

2010-04-01

review (Yoder et al., 2008) of the GPO performance, NASA continued the cooperative agreement with UCAR. Another external review ( Bybee et al., 2008) of...Submitted by the Program Office External Review Committee. Bybee , Rodger W. (Chair), 2008. NASA External Review of a GLOBE Proposal, The Globe

Traumatic Globe Subluxation and Intracranial Injury Caused by Bicycle Brake Handle.

Science.gov (United States)

Poroy, Ceren; Cibik, Cansu; Yazici, Bulent

2016-09-01

Penetration of a bicycle brake handle into the orbit is a rare and serious type of trauma. Globe subluxation due to such trauma has not been previously reported. A 10-year-old girl presented after falling from a bicycle, which resulted in the handbrake penetrating her right upper eyelid. On examination, the globe was subluxated anteriorly, there was no light perception, and the pupilla was fixed and dilated. Radiologic studies revealed orbitonasal fractures, hemorrhage, emphysema in the orbit and cranium, and rupture of the extraocular muscles. The globe was replaced into the orbit with the help of lateral cantholysis and orbital septotomy. During 22 months of follow-up, the globe remained intact, but total loss of vision, blepharoptosis, and extraocular motility restriction persisted. This case and previous reports show that bicycle brake handles can cause severe, penetrating orbital and cerebral traumas that can result in vision loss or fatality. Brake handles should be designed to protect bicyclists from such injuries.

The GLOBE Program in Alabama: A Mentoring Approach to State-wide Implementation

Science.gov (United States)

Cox, G. N.

2003-12-01

Established in 1997, the GLOBE in Alabama (GIA) partnership has trained more than 1,000 teachers in almost 500 schools - over 25% of the total number of K-12 schools in Alabama. Over those five years, GIA has strived to achieve recognition of GLOBE as the "glue" to Alabama's new education program, the Alabama Math, Science and Technology Initiative (AMSTI). In 2003, GIA trained over 370 AMSTI K-8 teachers at two AMSTI hub sites in north Alabama. As the AMSTI program grows with the addition of future hub sites (eleven are planned), GIA must ready itself to train thousands of AMSTI teachers during the two-week summer professional development institutes that are part of AMSTI. A key component of AMSTI is a mentoring program conducted by math and science specialists - classroom educators loaned to the AMSTI hub sites by the school systems each hub site serves. The AMSTI mentoring program mirrors the GIA mentoring model begun in 1999 that originally funded regional GLOBE master teachers to provide technical assistance, feedback, and coaching for other GLOBE teachers. In schools where GIA mentor teachers were working, nearly a 100% increase in GLOBE student data reporting was noted. The GIA mentors now work within the hub site framework to ensure implementation of GLOBE as an integrated part of AMSTI. With the continued support of the State of Alabama, GIA will establish a network of mentors who work with the AMSTI hub site specialists in providing support for all AMSTI teachers. GIA is administered by the National Space Science and Technology Center, a partnership between NASA and the State of Alabama's seven research universities. Operational funding for GIA has been provided by the University of Alabama in Huntsville's Earth System Science Center, the NASA Marshall Space Flight Center, the Alabama Space Grant Consortium, The Alabama Department of Economic and Community Affairs, the Alabama State Department of Education, and Legacy. GIA has been able to build on these

Traumatic eye ball luxation: A stepwise approach to globe salvage

Directory of Open Access Journals (Sweden)

Himika Gupta

2017-10-01

Full Text Available Craniofacial trauma is often associated with orbital and ocular injuries. We report a case of a 21-year-old male with motor vehicular accident, orbital roof blow-in fracture, cerebrospinal fluid (CSF leak, and left sided globe luxation with corneal abrasion and complete conjunctival denuding. The patient was managed by a multispeciality team and the eyeball was protected by amniotic membrane graft (AMG biological dressing with novel use of inverted sterile metallic bowl as mechanical protection till the patient stabilized. During surgery, eyeball was reposited and ocular surface was reconstructed using amniotic membrane and symblepharon ring. Surgical correction and plating of the facial fractures and dural repair with autologus tensor fascia lata was done. Post surgery ocular surface was intact, ocular motility was well preserved and the globe was prephthisical. Traumatic eyeball luxation is a rare, but dramatic presentation which may occur in a blow in fracture when the intra orbital volume reduces and expels the eye ball out of the socket. This may be associated with extra ocular muscle rupture or optic nerve avulsion. The visual prognosis is nil in majority cases. However, the management is targeted towards globe preservation in view of psychological benefit and ease of cosmetic or prosthetic rehabilitation. Knowing the mechanism of luxation helps to plan the management. A stepwise approach for globe salvage is recommended. Team efforts to take care of various morbidities with special steps to safeguard the eye help to optimize outcomes. Keywords: Traumatic eyeball luxation, Blow in orbital fractures, Amniotic membrane graft for ocular surface, Globe reposition

GLOBE and the Earth SySTEM Model in Teacher Preparation

Science.gov (United States)

Jabot, M.; Moore, J.; Dorofy, P.

2017-12-01

This presentation will share the growing body of work linking ArcMap and GLOBE and the Earth SySTEM approach in the development of preservice teachers. Our work is linking the power of ArcMap with the vast database of GLOBE in a unique way that links the power of geospatial technologies in shaping the planning for and delivery of science instruction in the P-5 classroom.

Drug-induced gingival enlargement: Series of cases

Directory of Open Access Journals (Sweden)

Isabella Manzur-Villalobos

2018-01-01

Full Text Available Introduction: Gingival enlargement (GA is a benign condition of the oral cavity that is characterized by the excessive growth of the gingiva in mass and volume. This lesion is not only caused by hereditary factors or poor oral hygiene, but also by the intake of medications, including antihypertensive, anticonvulsant and immunosuppressive drugs. Objective: To sensitize the prevention or early care in patients with pathologies that merit the use of antihypertensive and anticonvulsants in conjunction with the dentist, to treat or avoid the drug-induced gingival enlargement (DIGE. Materials and methods: A series of clinical cases of patients with gingival enlargement by various drugs are reported, including Phenytoin, Amlodipine and Nifedipine. Periodontal and gingivectomy hygienic phase measures were applied to obtain better effects. Results: Satisfactory results were obtained with a considerable decrease in DIGE. Conclusions: The integral management is important in conjunction with the treating physician to follow up the drug that can be generating gingival enlargement. It is necessary to employ an initial approach with strategies of periodontal hygiene, and in severe cases and, as last resort, the periodontal surgery with gingivectomy and gingivoplasty.

Enlarged Adenoids (For Parents)

Science.gov (United States)

... frequent "sinus" symptoms ongoing middle ear infections or middle ear fluid in a school-aged child If enlarged adenoids are suspected, the doctor may ... apnea repeated infections frequent sinus infections ear infections, ... your child's adenoids removed is especially important if repeated infections ...

Turning Content into Conversation: How The GLOBE Program is Growing its Brand Online

Science.gov (United States)

Zwerin, R.; Randolph, J. G.; Andersen, T.; Mackaro, J.; Malmberg, J.; Tessendorf, S. A.; Wegner, K.

2012-12-01

Social Media is now a ubiquitous way for individuals, corporations, governments and communities to communicate. However, the same does not hold quite as true for the science community as many science educators, thought leaders and science programs are either reluctant or unable to build and cultivate a meaningful social media strategy. This presentation will show how The GLOBE Program uses social media to disseminate messages, build a meaningful and engaged following and grow a brand on an international scale using a proprietary Inside-Out strategy that leverages social media platforms such as Facebook, LinkedIn, Twitter, YouTube and Blogs to significantly increase influencers on a worldwide scale. In addition, this poster presentation will be interactive, so viewers will be able to touch and feel the social experience. Moreover, GLOBE representatives will be on hand to talk viewers through how they can implement a social media strategy that will allow them to turn their content into meaningful conversation. About The GLOBE Program: GLOBE is a science and education program that connects a network of students, teachers and scientists from around the world to better understand, sustain and improve Earth's environment at local, regional and global scales. By engaging students in hands-on learning of Earth system science, GLOBE is an innovative way for teachers to get students of all ages excited about scientific discovery locally and globally. To date, more than 23 million measurements have been contributed to the GLOBE database, creating meaningful, standardized, global research-quality data sets that can be used in support of student and professional scientific research. Since beginning operations in 1995, over 58,000 trained teachers and 1.5 million students in 112 countries have participated in GLOBE. For more information or to become involved, visit www.globe.gov.

Whole-globe biomechanics using high-field MRI.

Science.gov (United States)

Voorhees, Andrew P; Ho, Leon C; Jan, Ning-Jiun; Tran, Huong; van der Merwe, Yolandi; Chan, Kevin; Sigal, Ian A

2017-07-01

The eye is a complex structure composed of several interconnected tissues acting together, across the whole globe, to resist deformation due to intraocular pressure (IOP). However, most work in the ocular biomechanics field only examines the response to IOP over smaller regions of the eye. We used high-field MRI to measure IOP induced ocular displacements and deformations over the whole globe. Seven sheep eyes were obtained from a local abattoir and imaged within 48 h using MRI at multiple levels of IOP. IOP was controlled with a gravity perfusion system and a cannula inserted into the anterior chamber. T2-weighted imaging was performed to the eyes serially at 0 mmHg, 10 mmHg, 20 mmHg and 40 mmHg of IOP using a 9.4 T MRI scanner. Manual morphometry was conducted using 3D visualization software to quantify IOP-induced effects at the globe scale (e.g. axial length and equatorial diameters) or optic nerve head scale (e.g. canal diameter, peripapillary sclera bowing). Measurement sensitivity analysis was conducted to determine measurement precision. High-field MRI revealed an outward bowing of the posterior sclera and anterior bulging of the cornea due to IOP elevation. Increments in IOP from 10 to 40 mmHg caused measurable increases in axial length in 6 of 7 eyes of 7.9 ± 5.7% (mean ± SD). Changes in equatorial diameter were minimal, 0.4 ± 1.2% between 10 and 40 mmHg, and in all cases less than the measurement sensitivity. The effects were nonlinear, with larger deformations at normal IOPs (10-20 mmHg) than at elevated IOPs (20-40 mmHg). IOP also caused measurable increases in the nasal-temporal scleral canal diameter of 13.4 ± 9.7% between 0 and 20 mmHg, but not in the superior-inferior diameter. This study demonstrates that high-field MRI can be used to visualize and measure simultaneously the effects of IOP over the whole globe, including the effects on axial length and equatorial diameter, posterior sclera displacement and bowing, and even

Engaging the Public in the Citizen Science GLOBE at Night Campaign

Science.gov (United States)

Walker, Constance E.; Sparks, R. T.; Pompea, S. M.

2011-05-01

The emphasis in the international star-hunting campaign, GLOBE at Night, is in bringing awareness to the public on issues of light pollution. Light pollution threatens not only observatory sites and our "right to starlight", but can affect energy consumption, wildlife and health. GLOBE at Night has successfully reached a few 100,000 citizen-scientists. What steps can be taken to improve it? To promote the campaign via popular social media, GLOBE at Night created Facebook and Twitter pages. To increase participation in the 2011 campaign, children and adults submitted their sky brightness measurements in real time with smart phones or tablets using the web application at www.globeatnight.org/webapp/. With smart phones and tablets, the location, date and time register automatically. For those without smart mobile devices, user-friendly tools on the GLOBE at Night report page were reconfigured to determine latitude and longitude more easily and accurately. To increase the robustness of the data, 2 new approaches were taken. GLOBE at Night prototyped an "Adopt a Street” program in Tucson. The aim was for people to adopt different major or semi-major streets and take measurements every mile or so for the length of the street. The grid of measurements would canvas the town, allowing for comparisons of light levels over time (hours, days, years) or search for dark sky oases or light polluted areas. The increase to 2 campaigns in 2011 re-enforces these studies. The intent is to offer the program year-round for seasonal studies. The data can also be used to compare with datasets on wildlife, health, and energy consumption. Recently, NOAO and the Arizona Game and Fish Department have started a project with GLOBE at Night data and bat telemetry to examine a dark skies corridor in Tucson where the endangered bats fly. In our presentation, results of our efforts are discussed.

The performance of a centrifugal fan with enlarged impeller

International Nuclear Information System (INIS)

Li Chunxi; Song Lingwang; Jia Yakui

2011-01-01

Highlights: → The influence of impeller enlargement is evaluated numerically and experimentally. → Variation equations of the operation points for enlarged impellers are derived. → Impeller enlargement leads to louder fan noise due to reduced impeller-volute gap. - Abstract: The influence of enlarged impeller in unchanged volute on G4-73 type centrifugal fan performance is investigated in this paper. Comparisons are conducted between the fan with original impeller and two larger impellers with the increments in impeller outlet diameter of 5% and 10% respectively in the numerical and experimental investigations. The internal characteristics are obtained by the numerical simulation, which indicate there is more volute loss in the fan with larger impeller. Experiment results show that the flow rate, total pressure rise, shaft power and sound pressure level have increased, while the efficiency have decreased when the fan operates with larger impeller. Variation equations on the performance of the operation points for the fan with enlarged impellers are suggested. Comparisons between experiment results and the trimming laws show that the trimming laws for usual situation can predict the performance of the enlarged fan impeller with less error for higher flow rate, although the situation of application is not in agreement. The noise frequency analysis shows that higher noise level with the larger impeller fan is caused by the reduced impeller-volute gap.

The performance of a centrifugal fan with enlarged impeller

Energy Technology Data Exchange (ETDEWEB)

Li Chunxi, E-mail: leechunxi@163.com [School of Energy and Power Engineering, North China Electric Power University, 071003 Baoding, Hebei (China); Song Lingwang [School of Energy and Power Engineering, North China Electric Power University, 071003 Baoding, Hebei (China); Jia Yakui [Hebei Electric Power Design and Research Institute, 050031 Shijiazhuang, Hebei (China)

2011-08-15

Highlights: {yields} The influence of impeller enlargement is evaluated numerically and experimentally. {yields} Variation equations of the operation points for enlarged impellers are derived. {yields} Impeller enlargement leads to louder fan noise due to reduced impeller-volute gap. - Abstract: The influence of enlarged impeller in unchanged volute on G4-73 type centrifugal fan performance is investigated in this paper. Comparisons are conducted between the fan with original impeller and two larger impellers with the increments in impeller outlet diameter of 5% and 10% respectively in the numerical and experimental investigations. The internal characteristics are obtained by the numerical simulation, which indicate there is more volute loss in the fan with larger impeller. Experiment results show that the flow rate, total pressure rise, shaft power and sound pressure level have increased, while the efficiency have decreased when the fan operates with larger impeller. Variation equations on the performance of the operation points for the fan with enlarged impellers are suggested. Comparisons between experiment results and the trimming laws show that the trimming laws for usual situation can predict the performance of the enlarged fan impeller with less error for higher flow rate, although the situation of application is not in agreement. The noise frequency analysis shows that higher noise level with the larger impeller fan is caused by the reduced impeller-volute gap.

Use of Macrolane VRF 30 in emicircumferential penis enlargement.

Science.gov (United States)

Sito, Giuseppe; Marlino, Sergio; Santorelli, Adriano

2013-02-01

Penis enlargement is increasingly in demand. Methods for penis enlargement can be classified into surgical, nonsurgical (filling), and mechanical. Each method has shown only relatively successful results. A new formulation of injectable, stabilized, hyaluronic acid (HA)-based, nonanimal gel is available that may have applications for this use. The authors propose a new technique for emicircumferential-injection filling of the penis and assess the safety and efficacy of this procedure compared with lipofilling. The authors retrospectively reviewed the charts of 83 patients who underwent penis enlargement with either their HA-injection technique or lipofilling between December 2007 and July 2011. Safety, efficacy, and patient satisfaction were assessed. The circumferential enlargement obtained from both techniques ranged from 3.2 to 4.5 cm, with a decrement during erection. In all patients, the increase in penis length ranged from 1.8 to 3.6 cm. No complications were seen in patients treated with HA, whereas 8 patients treated with lipofilling developed granuloma, and another experienced fat necrosis. The vast majority (n = 72) of patients reported being "very satisfied" with the results. The ideal technique for penis enlargement should be nonsurgical, with a satisfactory and predictable result, a low rate of complications, and long-term stability. Emicircumferential enlargement with HA filler meets these requirements. However, results have been durable but not definitive, and repeated treatment (with associated costs) is necessary.

Rock the Globe

CERN Multimedia

Laëtitia Pedroso

2010-01-01

Created in 2005, the Swiss rock band "Wind of Change" is now candidate for the Eurovision Song Contest 2011 with a new song " Night & Light " with the music video filmed at CERN.   With over 20 gigs under their belt and two albums already released, the five members of the band (Alex Büchi, vocals; Arthur Spierer, drums; David Gantner, bass; Romain Mage and Yannick Gaudy, guitar) continue to excite audiences. For their latest composition "Night & Light", the group filmed their music video in the Globe of Science and Innovation. Winning the Eurovision contest would be a springboard in their artistic career for these young musicians. The selection results will be available December 11, 2010.      

Normalization of Bilateral Adrenal Gland Enlargement after Treatment for Cryptococcosis

Directory of Open Access Journals (Sweden)

Yuka Muraoka

2017-01-01

Full Text Available Cryptococcosis usually occurs in immunocompromised patients and can cause enlargement of the adrenal glands, although the morphologic changes after treatment have not been reported in detail. We report the case of 24-year-old man with fevers, headaches, and impaired consciousness who had been treated with glucocorticoids for a protein-losing gastroenteropathy. The cerebrospinal fluid analysis revealed cryptococcal meningitis. Computed tomography showed bilateral adrenal enlargement. A retrospective analysis revealed that the enlargement had been detected 5 months before admission and gradually increased. The enlargement was improved with antifungal therapy and normalized 6 months later. This is the first report describing morphological changes in the adrenal glands associated with cryptococcal meningitis. Adrenal enlargement by cryptococcosis can be improved without any abnormal findings, including calcifications, which may be a unique characteristic from other diseases, including tuberculosis.

GLOBE Observer: A new tool to bring science activities and measurements home

Science.gov (United States)

Riebeek Kohl, H.; Murphy, T.

2016-12-01

The Global Learning and Observations to Benefit the Environment (GLOBE) Program is an international science and education program that provides students and the public worldwide with the opportunity to participate in data collection and the scientific process, and contribute meaningfully to our understanding of the Earth system and global environment. For more than 20 years, GLOBE-trained teachers have been leading environmental data collection and student research in the classroom. In 2016, GLOBE expanded to invite data collection from citizen scientists of all ages through a simple smart phone app. The app makes it possible for students to take GLOBE data (environmental observations) outside of school with their families. It enables a museum, park, youth organization, or other informal institution to provide a simple take-home activity that will keep patrons engaged in environmental science from home. This presentation will provide a demonstration of the app and will provide examples of its use in informal settings.

Ubx regulates differential enlargement and diversification of insect hind legs.

Directory of Open Access Journals (Sweden)

Najmus Mahfooz

2007-09-01

Full Text Available Differential enlargement of hind (T3 legs represents one of the hallmarks of insect evolution. However, the actual mechanism(s responsible are yet to be determined. To address this issue, we have now studied the molecular basis of T3 leg enlargement in Oncopeltus fasciatus (milkweed bug and Acheta domesticus (house cricket. In Oncopeltus, the T3 tibia displays a moderate increase in size, whereas in Acheta, the T3 femur, tibia, and tarsus are all greatly enlarged. Here, we show that the hox gene Ultrabithorax (Ubx is expressed in the enlarged segments of hind legs. Furthermore, we demonstrate that depletion of Ubx during embryogenesis has a primary effect in T3 legs and causes shortening of leg segments that are enlarged in a wild type. This result shows that Ubx is regulating the differential growth and enlargement of T3 legs in both Oncopeltus and Acheta. The emerging view suggests that Ubx was co-opted for a novel role in regulating leg growth and that the transcriptional modification of its expression may be a universal mechanism for the evolutionary diversification of insect hind legs.

Pediatric open globe injury: A review of the literature

Directory of Open Access Journals (Sweden)

Xintong Li

2015-01-01

Full Text Available Open globe injury (OGI is a severe form of eye trauma estimated at 2-3.8/100,000 in the United States. Most pediatric cases occur at home and are the result of sharp object penetration. The aim of this article is to review the epidemiology, diagnosis, management, and prognosis of this condition by conducting a systematic literature search with inclusion of all case series on pediatric OGI published between 1996 and 2015. Diagnosis of OGI is based on patient history and clinical examination supplemented with imaging, especially computed tomography when indicated. Few prospective studies exist for the management of OGI in pediatric patients, but adult recommendations are often followed with success. The main goals of surgical management are to repair the open globe and remove intraocular foreign bodies. Systemic antibiotics are recommended as medical prophylaxis against globe infection, or endophthalmitis. Other complications are similar to those seen in adults, with the added focus of amblyopia therapy in children. Severe vision decline is most likely due to traumatic cataracts. The ocular trauma score, a system devised to predict final visual acuity (VA in adults, has proven to be of prognostic value in pediatric OGI as well. Factors indicating poor visual prognosis are young age, poor initial VA, posterior eye involvement, long wound length, globe rupture, lens involvement, vitreous hemorrhage, retinal detachment, and endophthalmitis. A thorough understanding of OGI and the key differences in epidemiology, diagnosis, management, and prognosis between adults and children is critical to timely prevention of posttraumatic vision loss early in life.

Globe hosts launch of new processor

CERN Multimedia

2006-01-01

Launch of the quadecore processor chip at the Globe. On 14 November, in a series of major media events around the world, the chip-maker Intel launched its new 'quadcore' processor. For the regions of Europe, the Middle East and Africa, the day-long launch event took place in CERN's Globe of Science and Innovation, with over 30 journalists in attendance, coming from as far away as Johannesburg and Dubai. CERN was a significant choice for the event: the first tests of this new generation of processor in Europe had been made at CERN over the preceding months, as part of CERN openlab, a research partnership with leading IT companies such as Intel, HP and Oracle. The event also provided the opportunity for the journalists to visit ATLAS and the CERN Computer Centre. The strategy of putting multiple processor cores on the same chip, which has been pursued by Intel and other chip-makers in the last few years, represents an important departure from the more traditional improvements in the sheer speed of such chips. ...

Multidetector CT (MD-CT) in the diagnosis of uncertain open globe injuries

Energy Technology Data Exchange (ETDEWEB)

Hoffstetter, P.; Schreyer, A.G.; Jung, E.M.; Heiss, P.; Zorger, N. [Inst. fuer Roentgendiagnostik, Universitaetsklinikum Regensburg (Germany); Schreyer, C.I.; Framme, C. [Klink und Poliklinik fuer Augenheilkunde, Universitaetsklinikum Regensburg (Germany)

2010-02-15

Purpose: To evaluate the significance of multislice CT for the diagnosis of uncertain penetrating globe injuries. Materials and Methods: Based on a retrospective chart review between 2002 and 2007, we identified 59 patients presenting with severe ocular trauma with uncertain rupture of the globe due to massive subconjunctival and/or anterior chamber hemorrhage. The IOP (intraocular pressure) was within normal range in all patients. High resolution multidetector CT (MD-CT) scans (16 slice scans) with axial and coronar reconstructions were performed in all patients. The affected eye was examined for signs of penetrating injury such as abnormal eye shape, scleral irregularities, lens dislocation or intravitreal hemorrhages. Four experienced radiologists read the CT scans independently. Beside the diagnosis, the relevant morphological criteria and the optimal plane orientation (axial or coronar) were specified. The sensitivity, specificity, and negative and positive predictive value were calculated. Additionally the interobserver variability was determined by applying the Cohen's kappa test. Surgical sclera inspections were performed in all cases as a standard of reference. The evaluations of the CT examination were compared with the surgery reports. Results: 59 patients were evaluated (42 men, 17 women). The mean age was 29 years (range 7-91). In 17 patients a rupture of the globe was diagnosed during surgery. 12 of these 17 penetrating injuries (70.6%) were classified correctly by MDCT, 5 of the 17 (29.4%) were not detectable. 42 patients did not have an open globe injury. 41 of these patients were diagnosed correctly negative by MDCT, and one patient was classified false positive. This results in a sensitivity of 70% with a specificity of 98%. There was high inter-rater agreement with kappa values between 0.89-0.96. Most discrepancies were caused by wrong negative findings. The most frequent morphologic criteria for open globe injury were the deformation (n

Globalisation or Journay into the Second Discovery of the Globe

OpenAIRE

Rodin, Davor

2003-01-01

The author claims that the globe was discovered by courageous adventurers and visionaries who had trust in geographical utopia that the Earth was round so they plunged into the unknown in their wretched sailboats. This stage ended in foundation of huge colonial empires but, eventually, this kind of violent colonization failed. What has been left from the first discovery of the globe? The most important reminder is discovery of identities of the former colonized peoples as well as the identity...

THE CRUCIAL THEMES OF EU ENLARGEMENT

Directory of Open Access Journals (Sweden)

Jacques Pelkmans

2001-12-01

Full Text Available This article provides a critical review of the “terms” of the ongoing EU enlargement, in the light of the European public interest. The European public interest ought to include the prospective (Central European members, within a perspective of an enlarged Union in 2010, or so. The following forms a personalised summary of a major report published (in Dutch in September 2001 by the WRR in The Hague (a think-tank, formally under the Dutch Prime Minister, but by statute fully independent. The author was one of the lead-writers of this report. The present article merely focuses on the policy recommendations of the report. It is hoped that these kinds of critical analyses will help to stimulate solid policy debate on the EU in Romania, on the road to EU membership. The article discusses why the notion of a “core-acquis” would improve the enlargement strategy; the application of the core acquis to the internal market, environment and justice and home affairs; judicial and administrative capacity; accession to “euro-land”; the rapid reform of the CAP; a reform of “cohesion” approaches; and a note on the EU budgetary implications.

Dagik Earth: A Digital Globe Project for Classrooms, Science Museums, and Research Institutes

Science.gov (United States)

Saito, A.; Tsugawa, T.

2017-12-01

Digital globe system is a powerful tool to make the audiences understand phenomena on the Earth and planets in intuitive way. Geo-cosmos of Miraikan, Japan uses 6-m spherical LED, and is one of the largest systems of digital globe. Science on a Sphere (SOS) by NOAA is a digital globe system that is most widely used in science museums around the world. These systems are so expensive that the usage of the digital globes is mainly limited to large-scale science museums. Dagik Earth is a digital globe project that promotes educational programs using digital globe with low cost. It aims to be used especially in classrooms. The cost for the digital globe of Dagik Earth is from several US dollars if PC and PC projector are available. It uses white spheres, such as balloons and balance balls, as the screen. The software is provided by the project with free of charge for the educational usage. The software runs on devices of Windows, Mac and iOS. There are English and Chinese language versions of the PC software besides Japanese version. The number of the registered users of Dagik Earth is about 1,400 in Japan. About 60% of them belongs to schools, 30% to universities and research institutes, and 8% to science museums. In schools, it is used in classes by teachers, and science activities by students. Several teachers have used the system for five years and more. In a students' activity, Dagik Earth contents on the typhoon, solar eclipse, and satellite launch were created and presented in a school festival. This is a good example of the usage of Dagik Earth for STEM education. In the presentation, the system and activity of Dagik Earth will be presented, and the future expansion of the project will be discussed.

Openwebglobe - AN Open Source Sdk for Creating Large-Scale Virtual Globes on a Webgl Basis

Science.gov (United States)

Loesch, B.; Christen, M.; Nebiker, S.

2012-07-01

This paper introduces the OpenWebGlobe project (www.openwebglobe.org) and the OpenWebGlobe SDK (Software Development Kit) - an open source virtual globe environment using WebGL. Unlike other (web-based) 3d geovisualisation technologies and toolkits, the OpenWebGlobe SDK not only supports the content authoring and web visualization aspects, but also the data processing functionality for generating multi-terabyte terrain, image, map and 3d point cloud data sets in high-performance and cloud-based parallel computing environments. The OpenWebGlobe architecture is described and the paper outlines the processing and the viewer functionality provided by the OpenWebGlobe SDK. It then discusses the generation and updating of a global 3d base map using OpenStreetMap data and finally presents two show cases employing the technology a) for implementing an interactive national 3d geoportal incorporating high resolution national geodata sets and b) for implementing a 3d geoinformation service supporting the real-time incorporation of 3d point cloud data.

Two-point resistance of a resistor network embedded on a globe.

Science.gov (United States)

Tan, Zhi-Zhong; Essam, J W; Wu, F Y

2014-07-01

We consider the problem of two-point resistance in an (m-1) × n resistor network embedded on a globe, a geometry topologically equivalent to an m × n cobweb with its boundary collapsed into one single point. We deduce a concise formula for the resistance between any two nodes on the globe using a method of direct summation pioneered by one of us [Z.-Z. Tan, L. Zhou, and J. H. Yang, J. Phys. A: Math. Theor. 46, 195202 (2013)]. This method is contrasted with the Laplacian matrix approach formulated also by one of us [F. Y. Wu, J. Phys. A: Math. Gen. 37, 6653 (2004)], which is difficult to apply to the geometry of a globe. Our analysis gives the result in the form of a single summation.

GIS Function Coupling for Virtual Globes, Phase I

Data.gov (United States)

National Aeronautics and Space Administration — Virtual Globe (VG) systems such as Google Earth, NASA World Winds and Microsoft Virtual Earth provide captivating animated 3D visualizations and support user queries...

Prevalence of enlarged mediastinal lymph nodes in heavy smokers - a comparative study

Energy Technology Data Exchange (ETDEWEB)

Kirchner, Johannes; Lorenz, Vivian-Wilma [Allgemeines Krankenhaus Hagen, Department of Diagnostic and Interventional Radiology, Hagen (Germany); Kirchner, Esther Maria [Staedtisches Klinikum Wedau, Clinic for Medicine, Duisburg (Germany); Goltz, Jan Peter; Kickuth, Ralph [University Hospital of Wuerzburg, Department of Radiology, Wuerzburg (Germany)

2011-08-15

To evaluate the frequency of enlarged hilar or mediastinal lymph nodes in heavy smokers (more than 10 pack years) compared with non- smokers. In a prospective study the CT findings of 88 consecutive patients (44 heavy smokers, 44 non- smokers) were analysed. Exclusion criteria were history of thoracic malignancy, sarcoidosis, occupational dust exposure or clinical evidence of pneumonia. Prevalence, size and site of enlarged lymph nodes were assessed by multidetector computed tomography (MDCT) and correlated with the cigarette consumption and the CT- findings of bronchitis and emphysema. Twenty-three of the 44 heavy smokers (52%) showed enlarged mediastinal lymph nodes. Non- smokers showed enlarged lymph nodes in 9% (4/44). The most common site of enlarged lymph nodes was the regional station 7 according to the ATS mapping (subcarinal). The difference between the frequency of enlarged lymph nodes in heavy smokers and non- smokers was significant (chi- square 19.3, p < 0.0001). Airway wall thickening and emphysema were often associated with an increased number of enlarged nodes. The present study demonstrates that enlarged mediastinal lymph nodes may occur in a rather high percentage of heavy smokers, especially in those with a MDCT finding of severe bronchitis. (orig.)

Prevalence of enlarged mediastinal lymph nodes in heavy smokers - a comparative study

International Nuclear Information System (INIS)

Kirchner, Johannes; Lorenz, Vivian-Wilma; Kirchner, Esther Maria; Goltz, Jan Peter; Kickuth, Ralph

2011-01-01

To evaluate the frequency of enlarged hilar or mediastinal lymph nodes in heavy smokers (more than 10 pack years) compared with non- smokers. In a prospective study the CT findings of 88 consecutive patients (44 heavy smokers, 44 non- smokers) were analysed. Exclusion criteria were history of thoracic malignancy, sarcoidosis, occupational dust exposure or clinical evidence of pneumonia. Prevalence, size and site of enlarged lymph nodes were assessed by multidetector computed tomography (MDCT) and correlated with the cigarette consumption and the CT- findings of bronchitis and emphysema. Twenty-three of the 44 heavy smokers (52%) showed enlarged mediastinal lymph nodes. Non- smokers showed enlarged lymph nodes in 9% (4/44). The most common site of enlarged lymph nodes was the regional station 7 according to the ATS mapping (subcarinal). The difference between the frequency of enlarged lymph nodes in heavy smokers and non- smokers was significant (chi- square 19.3, p < 0.0001). Airway wall thickening and emphysema were often associated with an increased number of enlarged nodes. The present study demonstrates that enlarged mediastinal lymph nodes may occur in a rather high percentage of heavy smokers, especially in those with a MDCT finding of severe bronchitis. (orig.)

Traumatic Globe Subluxation and Intracranial Injury Caused by Bicycle Brake Handle

OpenAIRE

Poroy; Cibik; Yazici

2016-01-01

Introduction Penetration of a bicycle brake handle into the orbit is a rare and serious type of trauma. Globe subluxation due to such trauma has not been previously reported. Case Presentation A 10-year-old girl presented after falling from a bicycle, which resulted in the handbrake penetrating her right upper eyelid. On examination, the globe was subluxated anteriorly, there was no light perception, and the pupilla was fixed and ...

The CinéGlobe film festival opens at CERN and the Forum Meyrin theatre

CERN Multimedia

CERN Bulletin

2010-01-01

The second edition of CinéGlobe, the international festival of short films and science documentaries, will be held from 16 to 20 February 2010. It is being organised by the club Open Your Eyes Films, CERN and the culture office of the city of Meyrin. For five days, 80 films from amongst the 700 submissions will be shown at the Globe of Science and Innovation and in the Forum Meyrin theatre. On Saturday, 20 February 2010, a jury composed of film professionals and public figures will award a Golden CinéGlobe for the best film in each category, along with an audience award, at a ceremony in the Globe of Science and Innovation. The festival programme is available for download. See you at the movies!

Interactive Visualization and Analysis of Geospatial Data Sets - TrikeND-iGlobe

Science.gov (United States)

Rosebrock, Uwe; Hogan, Patrick; Chandola, Varun

2013-04-01

The visualization of scientific datasets is becoming an ever-increasing challenge as advances in computing technologies have enabled scientists to build high resolution climate models that have produced petabytes of climate data. To interrogate and analyze these large datasets in real-time is a task that pushes the boundaries of computing hardware and software. But integration of climate datasets with geospatial data requires considerable amount of effort and close familiarity of various data formats and projection systems, which has prevented widespread utilization outside of climate community. TrikeND-iGlobe is a sophisticated software tool that bridges this gap, allows easy integration of climate datasets with geospatial datasets and provides sophisticated visualization and analysis capabilities. The objective for TrikeND-iGlobe is the continued building of an open source 4D virtual globe application using NASA World Wind technology that integrates analysis of climate model outputs with remote sensing observations as well as demographic and environmental data sets. This will facilitate a better understanding of global and regional phenomenon, and the impact analysis of climate extreme events. The critical aim is real-time interactive interrogation. At the data centric level the primary aim is to enable the user to interact with the data in real-time for the purpose of analysis - locally or remotely. TrikeND-iGlobe provides the basis for the incorporation of modular tools that provide extended interactions with the data, including sub-setting, aggregation, re-shaping, time series analysis methods and animation to produce publication-quality imagery. TrikeND-iGlobe may be run locally or can be accessed via a web interface supported by high-performance visualization compute nodes placed close to the data. It supports visualizing heterogeneous data formats: traditional geospatial datasets along with scientific data sets with geographic coordinates (NetCDF, HDF, etc

Open globe injury in Hospital Universiti Sains Malaysia - A 10-year review

Directory of Open Access Journals (Sweden)

Madhusudhan A/L Paramananda

2014-06-01

Full Text Available AIM: To identify the aetiology of open globe injuries at Hospital Universiti Sains Malaysia over a period of 10y and the prognostic factors for visual outcome.METHODS:Retrospective review of medical records of open globe injury cases that presented from January 2000 to December 2009. Classification of open globe injury was based on the Birmingham Eye Trauma Terminology (BETT. Records were obtained with hospital permission via the in-house electronic patient management system, and the case notes of all patients with a diagnosis of open globe injury were scrutinised. Patients with prior ocular trauma, pre-existing ocular conditions affecting the visual acuity, contrast sensitivity, central vision or corneal thickness, as well as those with a history of previous intraocular or refractive surgery were excluded. Analysis of data was with SPSS version 20.0. Ordinal logistic regression analysis was used to examine the association between prognostic factors and visual outcome.RESULTS: This study involved 220 patients (n=222 eyes. The most common place of injury was the home (51.8%, followed by the workplace (23.4%. Among children aged less than 16y of age, domestic-related injury was the predominant cause (54.6%, while in those aged 16y and above, occupational injuries were the most common cause (40.0%. Most eyes (76.5% had an initial visual acuity worse than 3/60, and in half of these, the visual acuity improved. The visual outcome was found to be significantly associated with the initial visual acuity (P<0.005, posterior extent of wound (P<0.001, length of wound (P<0.001, presence of hyphaema (P<0.001 and presence of vitreous prolapse ((P<0.005.CONCLUSION:The most common causes of open globe injury are domestic accidents and occupational injuries. Significant prognostic factors for final visual outcome in patients with open globe injury are initial visual acuity, posterior extent and length of wound, presence of hyphaema and presence of vitreous

Results from the Prototype GLOBE at Night Worldwide Light Pollution Observation Program

Science.gov (United States)

Walker, Constance E.; Pompea, S. M.; Isbell, D.; Orellana, D.; Blurton, C.; Henderson, S.

2006-06-01

Students, families, and educators worldwide participated in GLOBE at Night - an international event designed to observe and record the visible stars as a means of measuring light pollution in a given location. Participation was open to anyone - anywhere in the world - who could get outside and look skyward during the week of March 22-29, 2006. Our goal was 5000 observations from around the world in this prototype program.The hands-on learning activities associated with the program were designed to extend the traditional classroom and school day with a week of nighttime observations involving teachers, students and their families. By locating specific constellations in the sky, students from around the world learned how the lights in their community contribute to light pollution. Students explored the different light sources in their community learning the relationship between science, technology and society, and they reported their observations online through a central database allowing for authentic worldwide research and analysis. The observations made during GLOBE at Night helped students and scientists together assess how the quality of the night sky varies around the world as well as the level of energy wastage associated with poorly-shielded lights.For more information, visit http://www.globe.gov/globeatnight.GLOBE at Night is a collaboration between The GLOBE Program, the National Optical Astronomy Observatory (NOAO), Centro de Apoyo a la Didactica de la Astronomia (CADIAS) in Chile , Windows to the Universe, and Environmental Systems Research Institute, Inc. (ESRI).

Doorkeepers and Gatecrashers: EU Enlargement and Negotiation Strategies

DEFF Research Database (Denmark)

Brücker, Herbert; Schröder, Philipp; Weise, Christian

2004-01-01

This paper discusses the eastward enlargement process of the EU in the framework of a simple war of attrition bargaining game. Both players -- the existing EU members and the applicants -- benefit from enlargement, yet for the applicants, reform to the acquis is costly, while the EU prefers subst...... the benefits for new members are all effective negotiation strategies for the EU that have been applied in the process....

Planning and Management of Real-Time Geospatialuas Missions Within a Virtual Globe Environment

Science.gov (United States)

Nebiker, S.; Eugster, H.; Flückiger, K.; Christen, M.

2011-09-01

This paper presents the design and development of a hardware and software framework supporting all phases of typical monitoring and mapping missions with mini and micro UAVs (unmanned aerial vehicles). The developed solution combines state-of-the art collaborative virtual globe technologies with advanced geospatial imaging techniques and wireless data link technologies supporting the combined and highly reliable transmission of digital video, high-resolution still imagery and mission control data over extended operational ranges. The framework enables the planning, simulation, control and real-time monitoring of UAS missions in application areas such as monitoring of forest fires, agronomical research, border patrol or pipeline inspection. The geospatial components of the project are based on the Virtual Globe Technology i3D OpenWebGlobe of the Institute of Geomatics Engineering at the University of Applied Sciences Northwestern Switzerland (FHNW). i3D OpenWebGlobe is a high-performance 3D geovisualisation engine supporting the web-based streaming of very large amounts of terrain and POI data.

Surgical management of generalized gingival enlargement - a case series

International Nuclear Information System (INIS)

Akhtar, M.U.; Nazir, A.; Montmorency College of Dentistry, Lahore; Kiran, S.; Montmorency College of Dentistry, Lahore

2014-01-01

Generalized gingival enlargement is characterized by massive and exuberant gingival overgrowth that poses social, aesthetic, phonetic and functional problems for the patient. Therefore, it requires meticulous management. Objective: To describe the surgical management of generalized gingival enlargement by electrosurgical excision of patients presenting to a tertiary care centre. Study Design: Case series. Materials and Methods: The study was conducted at the Department of Oral and Maxillofacial Surgery, de'Montmorency College of Dentistry, Lahore, from January 2010 to December 2012. A total of sixteen patients were operated by using electrosurgical approach under general anaesthesia for surgical excision of generalized gingival enlargement. Results: All of the sixteen patients, 11 males and 5 females, showed excellent healing postoperatively without any recurrent gingival overgrowth. Discussion: To the best of our knowledge, the current study presents the largest case series of generalized gingival enlargement. Most of these cases were with massive disease due to lack of information of the study population about their disease, delay in referral by the general dental practitioners, painless and innocent nature of the problem. Early referral of such patients to tertiary care centers can prevent the patients from social and psychological embarrassment. Conclusion: Electrosurgical excision is an excellent surgical technique for management of generalized gingival enlargement. Moreover, cross comparative studies are required to establish some diagnostic and therapeutic standards for such patients. (author)

Using Digital Globes to Explore the Deep Sea and Advance Public Literacy in Earth System Science

Science.gov (United States)

Beaulieu, Stace E.; Emery, Emery; Brickley, Annette; Spargo, Abbey; Patterson, Kathleen; Joyce, Katherine; Silva, Tim; Madin, Katherine

2015-01-01

Digital globes are new technologies increasingly used in informal and formal education to display global datasets and show connections among Earth systems. But how effective are digital globes in advancing public literacy in Earth system science? We addressed this question by developing new content for digital globes with the intent to educate and…

Experimental investigation of impingement cooling with turbulators or surface enlarging elements

Energy Technology Data Exchange (ETDEWEB)

Persson, Johan

2000-02-01

For the materials in modern gas turbines to sustain, a considerable amount of cooling is required. In cases where large amounts of heat need to be removed, impingement cooling with its high heat transfer coefficients may be the only alternative. In this work the possibilities of enhancing impingement cooling by introducing surface enlarging - turbulence enhancing elements are examined experimentally. A configuration consisting of a staggered array of 45 impingement jets distributed over 10 rows is used for the purpose. A thermo camera is used to measure the temperature distribution on the target plate, giving an opportunity to separately evaluate the Nusselt number enhancement for different areas. Experiments are conducted for five different area enlarging geometries: triangle, wing, cylinder, dashed rib, and angel, all made from aluminium. Comparison between each area enlarged surface and a flat plate is made, with results presented as Nusselt number enhancement factors. The effect of pumping power required is also investigated in order to maximize the cooling efficiency. Parameters varied are Reynolds number and jet to plate distance. Overall Nusselt number enhancement factors show values of 1 to 1.3, the trend being decreasing with increased jet to plane distance and Reynolds number. When taking into account pumping power the enhancement factors drop to 0.4 to 1.2. The best results are achieved with the rib geometry and when not using a too large value of enlarger height over jet to plate distance (h/z). Row wise evaluation of Nusselt number enhancement shows an increased enhancement with row number and thereby crossflow ratio (Gc/Gj). Typical increases in enhancement of 1 to 1.5 with Gc/Gj from 0 to 0.8 are found. The thermo camera pictures reveal that the enhancement is found in three different areas, on the enlarger base area, the area just downstream the enlarger and in diagonal streaks with increased turbulence caused by the enlargers. Tests using an

Analysis of the number of enlarged pores according to site, age, and sex.

Science.gov (United States)

Jung, H J; Ahn, J Y; Lee, J I; Bae, J Y; Kim, H L; Suh, H Y; Youn, J I; Park, M Y

2018-02-02

Increasing the number of enlarged pores causes cosmetic problems. The difference in the number of enlarged pores according to facial site, age, and sex is unclear. To analyze the distribution of the number of enlarged pores according to facial site, age, and sex. We analyzed the number of the enlarged pores and the percentage of wrinkles in the nose, forehead, and cheek from 434 polarized images. The measurement results were analyzed according to site, age, and sex. Relationship between enlarged pore counts and wrinkle severity was also analyzed. The study was conducted by using DermaVision,™ which can take cross-polarization, parallel polarization, and ultraviolet light images. The enlarged pores of the nose and forehead were more prominent than in the cheeks. Pore counts were increased with age, and the increment was significant between the 30's and 40's. There was no significant difference by gender. Enlarged pore counts were related to wrinkle severity. The number of enlarged pores differs depending on body site and increased with age. The enlarged pore counts correlate with wrinkle severity and the correlation varies depending on the body site. © 2018 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

The new Globe car park: for visitors and the CERN community

CERN Multimedia

2014-01-01

With twice as many parking spaces as the existing car park by the flagpoles and the same conditions of use (see here), the new Globe car park will be open for use from Monday 5 May.   The new Globe car park: the blue spaces are reserved for P+R pass holders. The new car park, which will be inaugurated on Monday 28 April by CERN’s Director-General in the presence of officials representing the Canton of Geneva and the sub-prefecture of the Ain, will better cater to the needs of CERN’s many visitors. The large number of spaces (around 100) reserved for P+R users will encourage the use of public transport, which will be particularly important at peak times. From autumn 2014, the Globe car park will completely replace the flagpole car park, where the new Esplanade des Particules will be built.

The Globe of Science and Innovation at dawn

CERN Multimedia

Maximilien Brice

2006-01-01

CERN's exhibition centre 'the Globe of Science and Innovation' is seen just after sunrise. This wooden building was given to CERN in 2004 as a gift from the Swiss Confederation to mark 50 years since the Organisation's foundation.

Reincarnation platn of globe. Chikyu saisei keikaku ni tsuite

Energy Technology Data Exchange (ETDEWEB)

Matsuyama, T. (Agency of Natural Resources and Energy, Tokyo (Japan))

1990-11-30

The period of 200 years since the Industrial Revolution has taken for the occurence of global warming up problem, and it may require to face the problem comprehensively and for long period of 100 years unit to resolve it. This reincarnation plan of globe aims to reincarnate the changed global environment hereafter by using time of about 100 years, and proposes to make the comprehensive and long term actions to suppress and reduce exhaust gases resulting the greenhouse effect by the cooperation of all nations in the world. In the former 50 years, feasible countermeasures such as deepenung of scientific knowkedges, promotion of worldwide energy saving, introduction of clean energy, development of revolutional environmental technology, expansion of CO {sub 2} absorbing sources, and technological development of energy for the next generation will be executed continuously. In the latter 50 years, the gas exhausting amount resulting the green house effect will be reduced and suppressed from these results. Owing to these measures, the reduction of gas resulting the greenhouse effect which exceeds the expectation, can clean the globe after 100 years because the cleaning results will be incorporated into the natural circulation and the green globe will be reincarnated. 1 fig., 1 tab

The Globe of Science and Innovation at night

CERN Multimedia

Maximilien Brice

2005-01-01

The Globe of Science and Innovation, CERN's exhibition centre is seen lit up at night. This wooden building was given to CERN in 2004 as a gift from the Swiss Confederation to mark 50 years since the Organization's foundation.

Uurimuslik õpe GLOBE programmi näitel / Imbi Henno

Index Scriptorium Estoniae

Henno, Imbi

2005-01-01

Artiklis tutvustatakse põhi- ja keskkooliõpilastele mõeldud uurimuslikku õpet ja praktilisi tegevusi pakkuvat keskkonnasuunitlusega ülemaailmset haridus- ja teadusprogrammi GLOBE (Global Learning and Observations to Benefit Environment)

Voices from Around the Globe

Directory of Open Access Journals (Sweden)

Birgit Schreiber

2017-07-01

Full Text Available JSAA has been seeking to provide an opportunity for Student Affairs professionals and higher education scholars from around the globe to share their research and experiences of student services and student affairs programmes from their respective regional and institutional contexts. This has been given a specific platform with the guest-edited issue “Voices from Around the Globe” which is the result of a collaboration with the International Association of Student Affairs and Services (IASAS, and particularly with the guest editors, Kathleen Callahan and Chinedu Mba.

Observations of El Niño impacts using in situ GLOBE protocols and satellite data

Science.gov (United States)

Srinivasan, M. M.; Destaerke, D.

2015-12-01

The El Niño phenomenon is a periodic ocean condition that occurs every two to ten years in the central and east-central equatorial Pacific Ocean. It alters the normal patterns of ocean circulation, surface temperature, and evaporation, causing noticeable and often severe changes in weather conditions in many areas of the world. El Niño is the warm phase of the El Niño Southern Oscillation (ENSO), and usually reaches its peak between December and February time period. El Niño and its worldwide consequences are studied by the school network of the GLOBE Program (www.globe.gov) which brings together students, teachers, and scientists in support of student research and validation of international Earth science research projects. Since the start of the GLOBE Program over 20 years ago, GLOBE classrooms utilize carefully developed daily, weekly, or seasonally protocols such as maximum, minimum and current temperatures, rainfall, soil moisture, and others, to measure changes in the environment. The data collected by the students is entered in an online GLOBE database. In addition to the student-contributed data, automated stations also collect and send measurements to the GLOBE database.Students compare their data with global data acquired by satellites to help validate the satellite data. With a potentially historic-level El Niño event thought to be on the horizon--possibly one of the strongest in 50 years—we will propose an emphasis on measurements from GLOBE schools that will support studies and satellite observations of El Niño. We plan to provide the schools with additional satellite data sets such as ocean temperature measurements from Advanced Very High Resolution Radiometer (AVHRR), sea surface elevation measurements from Jason-2 and 3 (after it launches), and others to be identified. We wish to address and support the following educational objectives: - Demonstrate how El Niño affects local precipitation and temperature across the globe, - Link teachers

New cropping designs for globe artichoke industry

Directory of Open Access Journals (Sweden)

Rosario Paolo Mauro

2011-03-01

Full Text Available A two-year experiment was carried-out in order to evaluate the effects of two plant arrangements (single vs. twin rows and four plant densities (1.0 -1.2 -1.4 and 1.8 plant m–2 on the agronomical behaviour and head characteristics of three globe artichoke genotypes (Violetto di Sicilia, Harmony F1 and Madrigal F1. The change of the cultivation format toward a high density stand significantly increase yield and yield synchronicity. The twin rows plant arrangement, although reduced total yield, increased the yield synchronicity. Moreover, the cultivation of seed-propagated genotypes (Harmony F1 and Madrigal F1 allowed extending significantly the availability of the heads across the year. On the basis of our results, we can assert that the implementation of a specific scheduling cultivation, based on higher density stands, twin rows plant arrangement and the integration of the traditional early genotypes with the new seed-propagated cultivars, is a promising way to match the requirements of a globe artichoke industrial crop, and to predispose a better mechanization of the cultural practices.

Individualism–Collectivism in Hofstede and GLOBE

OpenAIRE

Paul Brewer; Sunil Venaik

2011-01-01

This paper examines the Individualism–Collectivism (I-C) dimension of national culture in the Hofstede and GLOBE models. We identify major contradictions between the two culture models, which result in contradictory relationships with external variables such as economic prosperity. We critically evaluate the content validity of the items used to measure this construct in both models. Based on our analysis, we suggest that Hofstede's Individualism–Collectivism index be relabelled as Self-orien...

Aortic Annular Enlargement during Aortic Valve Replacement

Directory of Open Access Journals (Sweden)

Selman Dumani

2016-09-01

Full Text Available In the surgery of aortic valve replacement is always attempted, as much as possible, to implant the larger prosthesis with the mains goals to enhance the potential benefits, to minimise transvalvular gradient, decrease left ventricular size and avoid the phenomenon of patient-prosthesis mismatch. Implantation of an ideal prosthesis often it is not possible, due to a small aortic annulus. A variety of aortic annulus enlargement techniques is reported to avoid patient-prosthesis mismatch. We present the case that has submitted four three times open heart surgery. We used Manouguian technique to enlarge aortic anulus with excellent results during the fourth time of surgery.

WYSIWYG GEOPROCESSING: COUPLING SENSOR WEB AND GEOPROCESSING SERVICES IN VIRTUAL GLOBES

Directory of Open Access Journals (Sweden)

X. Zhai

2012-08-01

Full Text Available We propose to advance the scientific understanding and applications of geospatial data by coupling Sensor Web and Geoprocessing Services in Virtual Globes for higher-education teaching and research. The vision is the concept of "What You See is What You Get" geoprocessing, shortly known as WYSIWYG geoprocessing. Virtual Globes offer tremendous opportunities, such as providing a learning tool to help educational users and researchers digest global-scale geospatial information about the world, and acting as WYSIWYG platforms, where domain experts can see what their fingertips act in an interactive three-dimensional virtual environment. In the meantime, Sensor Web and Web Service technologies make a large amount of Earth observing sensors and geoprocessing functionalities easily accessible to educational users and researchers like their local resources. Coupling Sensor Web and geoprocessing Services in Virtual Globes will bring a virtual learning and research environment to the desktops of students and professors, empowering them with WYSIWYG geoprocessing capabilities. The implementation combines the visualization and communication power of Virtual Globes with the on-demand data collection and analysis functionalities of Sensor Web and geoprocessing services, to help students and researchers investigate various scientific problems in an environment with natural and intuitive user experiences. The work will contribute to the scientific and educational activities of geoinformatic communities in that they will have a platform that are easily accessible and help themselves perceive world space and perform live geoscientific processes.

Reversible enlargement of the hypophysis in clinically latent hypothyroidism

Energy Technology Data Exchange (ETDEWEB)

Schuemichen, C.

1982-12-01

A case is reported, in which the combination of high TT/sub 3/- and FT/sub 4/ plasma levels, increased TSH basal secretion and enlargement of the pituitary gland did not reflect secondary hyperthyroidism, but was cuased by clinically latent hypothyroidism, probably due to thyroid hormone antibodies. High doses of thyroid hormones lowered the TSH and prolactin basal secretion, and reduced the enlargement of the pituitary gland.

Reversible enlargement of the hypophysis in clinically latent hypothyroidism

International Nuclear Information System (INIS)

Schuemichen, C.

1982-01-01

A case is reported, in which the combination of high TT 3 - and FT 4 plasma levels, increased TSH basal secretion and enlargement of the pituitary gland did not reflect secondary hyperthyroidism, but was cuased by clinically latent hypothyroidism, probably due to thyroid hormone antibodies. High doses of thyroid hormones lowered the TSH and prolactin basal secretion, and reduced the enlargement of the pituitary gland. (orig.) [de

The EU and ‘Enlargement Fatigue’: Why Has the European Union Not Been Able to Counter ‘Enlargement Fatigue’?

Directory of Open Access Journals (Sweden)

Anna Szolucha

2010-05-01

Full Text Available This article provides an up-to-date overview of the problems connected with European integration. It focuses on the phenomenon of ‘enlargement fatigue’ and examines its meaning as utilised by the media, EU officials and academics. The article argues that ‘enlargement fatigue’ is not a new concept since the EU has witnessed many 'symptoms' of fatigue at multiple times in its history. The two main arguments that are often presented in order to explain why the EU has not been able to counter ‘enlargement fatigue’, namely the insufficiently tight conditionality applied to prospective members and the EU's crisis of confidence and accountability after the failed attempt to introduce the Constitutional Treaty and prolonged Lisbon Treaty ratification process, are insufficient to explain why fatigue has been so persistent a phenomenon. This article argues that the EU's failure to develop a new vision of the organisation and adjust its structural design accordingly is a reason why the Union has not dealt successfully with fatigue. Such a vision would encompass notions of “variable geometry”, “avant-garde groups” and make European borders flexible and fuzzy.

Nato enlarging into the Baltic States

Index Scriptorium Estoniae

2003-01-01

Prahas 21.-22. novembrini 2002 toimunud NATO tippkohtumisest ja seal vastu võetud otsusest Balti riikide alliansiga ühinemise kohta. Vt. samas: Russia's attitude to the NATO enlargement; Bush in Vilnius; Baltic states' prime ministers' met; Supporting USA?

Crowd-Sourcing with K-12 citizen scientists: The Continuing Evolution of the GLOBE Program

Science.gov (United States)

Murphy, T.; Wegner, K.; Andersen, T. J.

2016-12-01

Twenty years ago, the Internet was still in its infancy, citizen science was a relatively unknown term, and the idea of a global citizen science database was unheard of. Then the Global Learning and Observations to Benefit the Environment (GLOBE) Program was proposed and this all changed. GLOBE was one of the first K-12 citizen science programs on a global scale. An initial large scale ramp-up of the program was followed by the establishment of a network of partners in countries and within the U.S. Now in the 21st century, the program has over 50 protocols in atmosphere, biosphere, hydrosphere and pedosphere, almost 140 million measurements in the database, a visualization system, collaborations with NASA satellite mission scientists (GPM, SMAP) and other scientists, as well as research projects by GLOBE students. As technology changed over the past two decades, it was integrated into the program's outreach efforts to existing and new members with the result that the program now has a strong social media presence. In 2016, a new app was launched which opened up GLOBE and data entry to citizen scientists of all ages. The app is aimed at fresh audiences, beyond the traditional GLOBE K-12 community. Groups targeted included: scouting organizations, museums, 4H, science learning centers, retirement communities, etc. to broaden participation in the program and increase the number of data available to students and scientists. Through the 20 years of GLOBE, lessons have been learned about changing the management of this type of large-scale program, the use of technology to enhance and improve the experience for members, and increasing community involvement in the program.

Enlarged perivascular spaces and cognitive impairment after stroke and transient ischemic attack.

Science.gov (United States)

Arba, Francesco; Quinn, Terence J; Hankey, Graeme J; Lees, Kennedy R; Wardlaw, Joanna M; Ali, Myzoon; Inzitari, Domenico

2018-01-01

Background Previous studies suggested that enlarged perivascular spaces are neuroimaging markers of cerebral small vessel disease. However, it is not clear whether enlarged perivascular spaces are associated with cognitive impairment. We aimed to determine the cross-sectional relationship between enlarged perivascular spaces and small vessel disease, and to investigate the relationship between enlarged perivascular spaces and subsequent cognitive impairment in patients with recent cerebral ischemic event. Methods Anonymized data were accessed from the virtual international stroke trial archive. We rated number of lacunes, white matter hyperintensities, brain atrophy, and enlarged perivascular spaces with validated scales on magnetic resonance brain images after the index stroke. We defined cognitive impairment as a mini mental state examination score of ≤26, recorded at one year post stroke. We examined the associations between enlarged perivascular spaces and clinical and imaging markers of small vessel disease at presentation and clinical evidence of cognitive impairment at one year using linear and logistic regression models. Results We analyzed data on 430 patients with mean (±SD) age 64.7 (±12.7) years, 276 (64%) males. In linear regression analysis, age (β = 0.24; p cognitive impairment at one year after adjusting for clinical confounders (OR = 1.72, 95% CI = 1.22-2.42) and for clinical and imaging confounders (OR = 1.54; 95% CI = 1.03-2.31). Conclusions Our data show that in patients with ischemic cerebral events, enlarged perivascular spaces are cross-sectionally associated with age, hypertension, and white matter hyperintensities and suggest that enlarged perivascular spaces in the basal ganglia are associated with cognitive impairment after one year.

Citizen Scientist Contributions to Observations Benefiting the Earth through the GLOBE Program

Science.gov (United States)

Chambers, L. H.; Riebeek Kohl, H.; Murphy, A.; Butler, D. M.

2017-12-01

Citizen science has proliferated recently due to widespread use of the internet and mobile devices, but it has a long history (i.e., the Christmas Bird Count). Since the mid-1990s, the GLOBE Program has engaged participants at a global scale. Though initially focused on teachers and students in formal education settings, it quickly attracted interest from the public as well. In 2016, GLOBE formally launched an initiative to widely engage citizen scientists in its 117 countries through release of a mobile app called GLOBE Observer (GO). GO seeks to increase the number and distribution of participants by providing a simple, engaging - and fun - interface to collect and report data. Observations featured in the app are a carefully selected subset of 50+ GLOBE measurement protocols. They must leverage app features, require little to no equipment besides the mobile device, and have scientists or other stakeholders ready to use the data. The app is designed to minimize barriers to participation, but for those who want to do or know more GLOBE also offers on-line training to turn observers into community members with recognized certification in a protocol area. First released was a cloud observation protocol, supporting validation of a variety of Earth imaging sensors. Second was a mosquito habitat mapping protocol, poised to greatly increase the amount and distribution of local data to validate disease forecast models based on remotely sensed conditions, with additional focus on eliminating disease-carrying mosquito breeding sites. Next in development is a land cover protocol to obtain ground truth imagery for the Landsat science team. The app is also being leveraged for quick development of a short-term eclipse mini-app, to be used on August 21st only during the North American eclipse. This app is designed to make it easy for large numbers of people observing the eclipse, throughout North America, to take and record high time resolution observations of cloud cover and

The isolation and mapping of a novel hydroxycinnamoyltransferase in the globe artichoke chlorogenic acid pathway

Directory of Open Access Journals (Sweden)

Bourgaud Frédéric

2009-03-01

Full Text Available Abstract Background The leaves of globe artichoke and cultivated cardoon (Cynara cardunculus L. have significant pharmaceutical properties, which mainly result from their high content of polyphenolic compounds such as monocaffeoylquinic and dicaffeoylquinic acid (DCQ, and a range of flavonoid compounds. Results Hydroxycinnamoyl-CoA:quinate hydroxycinnamoyltransferase (HQT encoding genes have been isolated from both globe artichoke and cultivated cardoon (GenBank accessions DQ915589 and DQ915590, respectively using CODEHOP and PCR-RACE. A phylogenetic analysis revealed that their sequences belong to one of the major acyltransferase groups (anthranilate N-hydroxycinnamoyl/benzoyltransferase. The heterologous expression of globe artichoke HQT in E. coli showed that this enzyme can catalyze the esterification of quinic acid with caffeoyl-CoA or p-coumaroyl-CoA to generate, respectively, chlorogenic acid (CGA and p-coumaroyl quinate. Real time PCR experiments demonstrated an increase in the expression level of HQT in UV-C treated leaves, and established a correlation between the synthesis of phenolic acids and protection against damage due to abiotic stress. The HQT gene, together with a gene encoding hydroxycinnamoyl-CoA:shikimate/quinate hydroxycinnamoyltransferase (HCT previously isolated from globe artichoke, have been incorporated within the developing globe artichoke linkage maps. Conclusion A novel acyltransferase involved in the biosynthesis of CGA in globe artichoke has been isolated, characterized and mapped. This is a good basis for our effort to understand the genetic basis of phenylpropanoid (PP biosynthesis in C. cardunculus.

The isolation and mapping of a novel hydroxycinnamoyltransferase in the globe artichoke chlorogenic acid pathway

Science.gov (United States)

Comino, Cinzia; Hehn, Alain; Moglia, Andrea; Menin, Barbara; Bourgaud, Frédéric; Lanteri, Sergio; Portis, Ezio

2009-01-01

Background The leaves of globe artichoke and cultivated cardoon (Cynara cardunculus L.) have significant pharmaceutical properties, which mainly result from their high content of polyphenolic compounds such as monocaffeoylquinic and dicaffeoylquinic acid (DCQ), and a range of flavonoid compounds. Results Hydroxycinnamoyl-CoA:quinate hydroxycinnamoyltransferase (HQT) encoding genes have been isolated from both globe artichoke and cultivated cardoon (GenBank accessions DQ915589 and DQ915590, respectively) using CODEHOP and PCR-RACE. A phylogenetic analysis revealed that their sequences belong to one of the major acyltransferase groups (anthranilate N-hydroxycinnamoyl/benzoyltransferase). The heterologous expression of globe artichoke HQT in E. coli showed that this enzyme can catalyze the esterification of quinic acid with caffeoyl-CoA or p-coumaroyl-CoA to generate, respectively, chlorogenic acid (CGA) and p-coumaroyl quinate. Real time PCR experiments demonstrated an increase in the expression level of HQT in UV-C treated leaves, and established a correlation between the synthesis of phenolic acids and protection against damage due to abiotic stress. The HQT gene, together with a gene encoding hydroxycinnamoyl-CoA:shikimate/quinate hydroxycinnamoyltransferase (HCT) previously isolated from globe artichoke, have been incorporated within the developing globe artichoke linkage maps. Conclusion A novel acyltransferase involved in the biosynthesis of CGA in globe artichoke has been isolated, characterized and mapped. This is a good basis for our effort to understand the genetic basis of phenylpropanoid (PP) biosynthesis in C. cardunculus. PMID:19292932

Winter scene of the Globe of Science and Innovation

CERN Multimedia

patrice loiez

2005-01-01

CERN's Globe exhibition centre is shown on a Swiss winter day. This wooden building was given to CERN in 2004 as a gift from the Swiss Confederation to mark 50 years since the Organization's foundation.

Mitral-aortic annular enlargement: modification of Manouguian's technique

Directory of Open Access Journals (Sweden)

Costa Mario Gesteira

2002-01-01

Full Text Available We hereby present a technical modification for mitral-aortic annular enlargement. The mitral valve is replaced through the retro-septal approach, avoiding patches for left atrial roof closure. We report a mitral-aortic valve replacement in a patient whose original annuli would preclude adequate prostheses. The simultaneous annular enlargement may be necessary for avoiding patient-prosthesis mismatch and for reconstructing destroyed mitral and aortic annuli. The technique may minimize the risk of bleeding and of paravalvular leakage, using an approach well known to cardiac surgeons.

Research Progress of Global Land Domain Service Computing:Take GlobeLand 30 as an Example

Directory of Open Access Journals (Sweden)

CHEN Jun

2017-10-01

Full Text Available Combining service-computing technology with domain requirements is one of the important development directions of geographic information under Internet+, which provides highly efficient technical means for information sharing and collaborative services. Using GlobeLand 30 as an example, this paper analyzes the basic problems of integrating land cover information processing and service computing, introduces the latest research progress in domain service modeling, online computing method and dynamic service technology, and the GlobeLand 30 information service platform. The paper also discusses the further development directions of GlobeLand 30 domain service computing.

Strategy to avoid patient-prosthesis mismatch: aortic root enlargement.

Science.gov (United States)

Srivastava, Dharmendra Kumar; Sanki, Prokash; Bhattacharya, Subhankar; Siddique, Javed Veqar

2014-02-01

The choice of a valve with an effective orifice area matching the body surface area and providing efficient hemodynamics is an important factor affecting mortality and morbidity in patients undergoing aortic valve replacement. Our preventative strategy was to implant a larger prosthetic valve by aortic root enlargement using the Nunez procedure in 17 patients between February 2010 and January 2011. The decision to enlarge the aortic root was taken when the 19-mm sizer could not be negotiated easily through the aortic root, or on the basis of body surface area of the patient or type of prosthesis available. Postoperative reductions in peak and mean pressure gradients across aortic valve of 12.8-16.5 and 10.2-12.6 mm Hg, respectively, were observed. Postoperative effective orifice areas of the aortic valves were 1.1-1.5 cm(2). By upsizing the aortic valve, we were able to eliminate patient-prosthesis mismatch in 5 patients, and reduce severe patient-prosthesis mismatch to moderate in 11. Aortic root enlargement is a safe procedure. Therefore, cardiac surgeons should not be reluctant to enlarge the aortic root with an autologous pericardial patch to permit implantation of an adequate size of aortic valve prosthesis, with minimal additional aortic crossclamp time and no added cost.

A VIRTUAL GLOBE-BASED MULTI-RESOLUTION TIN SURFACE MODELING AND VISUALIZETION METHOD

Directory of Open Access Journals (Sweden)

X. Zheng

2016-06-01

Full Text Available The integration and visualization of geospatial data on a virtual globe play an significant role in understanding and analysis of the Earth surface processes. However, the current virtual globes always sacrifice the accuracy to ensure the efficiency for global data processing and visualization, which devalue their functionality for scientific applications. In this article, we propose a high-accuracy multi-resolution TIN pyramid construction and visualization method for virtual globe. Firstly, we introduce the cartographic principles to formulize the level of detail (LOD generation so that the TIN model in each layer is controlled with a data quality standard. A maximum z-tolerance algorithm is then used to iteratively construct the multi-resolution TIN pyramid. Moreover, the extracted landscape features are incorporated into each-layer TIN, thus preserving the topological structure of terrain surface at different levels. In the proposed framework, a virtual node (VN-based approach is developed to seamlessly partition and discretize each triangulation layer into tiles, which can be organized and stored with a global quad-tree index. Finally, the real time out-of-core spherical terrain rendering is realized on a virtual globe system VirtualWorld1.0. The experimental results showed that the proposed method can achieve an high-fidelity terrain representation, while produce a high quality underlying data that satisfies the demand for scientific analysis.

Ventricular enlargement in patients with affective disorders

International Nuclear Information System (INIS)

Murashita, Jun; Kato, Tadafumi; Shioiri, Toshiki; Hamakawa, Inubushi, Toshiro; Hiroshi; Takahashi, Saburo

1994-01-01

Ventricular enlargement was determined using linear measurement on MR images in a total of 71 patients with affective disorders, including bipolar affective disorder (41) and depression (30). Fourty-one healthy persons served as controls. Evans ratio, Huckman number and minimum distance of caudate nuclei (MDCN) were used as indices for ventricular enlargment. No significant difference in Evans ratio was observed between both the group of bipolar affective disorder and the group of depression and the control group. Nor did it correlate with age in any of the groups. Huckman number was significantly higher in the group of bipolar affective disorder than the other two groups. It positively correlated with age in the group of depression. MDCN was significantly increased in the group of bipolar affective disorder, as compared with the control group; and there was a positive correlation between MDCN and age in both the group of dipolar affective disorder and the group of depression. In conclusion, ventricular enlargement was dependent upon aging in affetive disorder patients. This tendency was more noticeable in the group of depression. In addition, atrophy of the caudate nuclei was likely to be severer in the group of dipolar affective disorder than the group of depression. (N.K.)

OceanGLOBE: an Outdoor Research and Environmental Education Program for K-12 Students

Science.gov (United States)

Perry, R. B.; Hamner, W. M.

2006-12-01

OceanGLOBE is an outdoor environmental research and education program for upper elementary, middle and high school students, supplemented by online instructional materials that are available without charge to any educator. OceanGLOBE was piloted in 1995 with support from a National Science Foundation Teacher Enhancement project, "Leadership in Marine Science" (award no.ESI-9454413 to UCLA). Continuing support by a second NSF Teacher Enhancement project (award no. ESI-9819424 to UCLA) and by COSEE-West (NSF awards OCE-215506 to UCLA and OCE-0215497 to USC) has enabled OceanGLOBE to expand to a growing number of schools and to provide an increasingly robust collection of marine science instructional materials on its website, http://www.msc.ucla.edu/oceanglobe/ OceanGLOBE provides a mechanism for students to conduct inquiry-based, hands-on marine science research, providing experiences that anchor the national and state science content standards learned in the classroom. Students regularly collect environmental and biological data from a beach site over an extended period of time. In the classroom they organize, graph and analyze their data, which can lead to a variety of student-created science products. Beach research is supported by instructional marine science materials on the OceanGLOBE website. These online materials also can be used in the classroom independent of the field component. Annotated PowerPoint slide shows explain research protocols and provide marine science content. Field guides and photographs of marine organisms (with emphasis on the Southern California Bight) and a growing collection of classroom investigations (applicable to any ocean location) support the science content presented in the beach research program and slide shows. In summary, OceanGLOBE is a comprehensive learning package grounded in hands-on, outdoor marine science research project in which students are the principal investigators. By doing scientific work repetitively over an

Effects of alternative cropping systems on globe artichoke qualitative traits.

Science.gov (United States)

Spanu, Emanuela; Deligios, Paola A; Azara, Emanuela; Delogu, Giovanna; Ledda, Luigi

2018-02-01

Traditionally, globe artichoke cultivation in the Mediterranean basin is based on monoculture and on use of high amounts of nitrogen fertiliser. This raises issues regarding its compatibility with sustainable agriculture. We studied the effect of one typical conventional (CONV) and two alternative cropping systems [globe artichoke in sequence with French bean (NCV1), or in biannual rotation (NCV2) with cauliflower and with a leguminous cover crop in inter-row spaces] on yield, polyphenol and mineral content of globe artichoke heads over two consecutive growing seasons. NCV2 showed statistical differences in terms of fresh product yield with respect to the monoculture systems. In addition, the dihydroxycinnamic acids and dicaffeoylquinic acids of non-conventional samples were one-fold significantly higher than the conventional one. All the samples reported good mineral content, although NCV2 achieved a higher Fe content than conventional throughout the two seasons. After two and three dates of sampling, the CONV samples showed the highest levels of K content. In our study, an acceptable commercial yield and quality of 'Spinoso sardo' were achieved by shifting the common conventional agronomic management to more sustainable ones, by means of an accurate choice of cover crop species and rotations introduced in the systems. © 2017 Society of Chemical Industry. © 2017 Society of Chemical Industry.

Calf enlargement associated with neurologic disease: two uncommon cases.

Science.gov (United States)

Harwood, S C; Honet, J C

1988-01-01

Muscle enlargement and hypertrophy are rare findings in neurogenic lesions. The two in combination have been reported in cases of peripheral nerve lesions, polyneuropathy, and poliomyelitis. True and pseudo muscle hypertrophy are the two possible etiologies, whereas infiltration, stretch, or exercise of the muscle are the causative factors. We report two cases of unilateral calf enlargement, one occurring after surgery for S1 radiculopathy with associated cramping, and the other after poliomyelitis.

Microbial cultures in open globe injuries in southern India.

Science.gov (United States)

Gupta, Arvind; Srinivasan, Renuka; Kaliaperumal, Subashini; Setia, Sajita

2007-07-01

To determine the risk factors leading to positive intraocular culture in patients with open globe injury. A prospective interventional study involving 110 eyes of 110 patients of more than 15 years of age, presenting with open globe injury, was undertaken. Emergency repair of the injured globe was done. Prolapsed intraocular tissue or aqueous humour was sent for microbial work up before repair. In endophthalmitis cases intravitreal antibiotics were given according to the antimicrobial sensitivity. Chi-square and logistic regression analysis were used to determine the risk factors. Fifty-six patients showed microbial contamination. Bacteria were cultured in 42 patients and fungi in 14 patients. Nineteen patients developed endophthalmitis, of which 18 patients showed microbial growth initially. In univariate analysis, initial visual acuity (8 mm, P 72 h, P 8 mm, P = 0.013) were associated with increased risk of positive microbial culture. Six patients had intraocular foreign body but were culture negative. Age, gender, site of injury and presence of cataract did not significantly affect the culture positivity. Microbial contamination is a risk factor for the development for endophthalmitis. Despite the high frequency of microbial contamination, it develops only in few cases. Systemic antibiotics, virulence of the organism and host factors play a role in the manifestation of endophthalmitis. Prophylaxis with intraocular antibiotics should be strongly considered in cases with poor vision at presentation, larger corneoscleral laceration, delayed surgical intervention and uveal tissue or vitreous prolapse.

Penile Enlargement : From Medication to Surgery

NARCIS (Netherlands)

Nugteren, Helena M.; Balkema, G. T.; Pascal, A. L.; Schultz, W. C. M. Weijmar; Nijman, J. M.; Van Driel, M. F.

2010-01-01

Penis lengthening pills, stretch apparatus, vacuum pumps, silicone injections, and lengthening and thickening operations are available for men who worry about their penis size. Surgery is thus far the only proven scientific method for penile enlargement. In this article, we consider patient

Visualizing dynamic geosciences phenomena using an octree-based view-dependent LOD strategy within virtual globes

Science.gov (United States)

Li, Jing; Wu, Huayi; Yang, Chaowei; Wong, David W.; Xie, Jibo

2011-09-01

Geoscientists build dynamic models to simulate various natural phenomena for a better understanding of our planet. Interactive visualizations of these geoscience models and their outputs through virtual globes on the Internet can help the public understand the dynamic phenomena related to the Earth more intuitively. However, challenges arise when the volume of four-dimensional data (4D), 3D in space plus time, is huge for rendering. Datasets loaded from geographically distributed data servers require synchronization between ingesting and rendering data. Also the visualization capability of display clients varies significantly in such an online visualization environment; some may not have high-end graphic cards. To enhance the efficiency of visualizing dynamic volumetric data in virtual globes, this paper proposes a systematic framework, in which an octree-based multiresolution data structure is implemented to organize time series 3D geospatial data to be used in virtual globe environments. This framework includes a view-dependent continuous level of detail (LOD) strategy formulated as a synchronized part of the virtual globe rendering process. Through the octree-based data retrieval process, the LOD strategy enables the rendering of the 4D simulation at a consistent and acceptable frame rate. To demonstrate the capabilities of this framework, data of a simulated dust storm event are rendered in World Wind, an open source virtual globe. The rendering performances with and without the octree-based LOD strategy are compared. The experimental results show that using the proposed data structure and processing strategy significantly enhances the visualization performance when rendering dynamic geospatial phenomena in virtual globes.

A study on the impact of the GLOBE program on students' attitudes regarding environmental issues

Science.gov (United States)

Manfready, Gary Martin

A key objective in environmental curricula should be to instill responsible and concerned attitudes toward environmental issues. This can be accomplished through the application of innovative programs which emphasize the development of the affective domain of learning. The development of personal attitudes is one form of evidence that the affective domain is being addressed. This study was undertaken to determine the impact of the GLOBE program (Global Learning and Observation to Benefit the Environment) on the attitudes of students toward environmental issues. Three hundred and five middle and high school level students from four states were surveyed to determine their attitudes toward selected environmental statements. Results demonstrated that attitudes toward environmental issues of GLOBE students were significantly greater than non-GLOBE students. Additional analysis demonstrated that regardless of grade levels, gender, racial and ethnicity backgrounds, depth of GLOBE involvement, and degree of teachers' GLOBE experiences, GLOBE students display similar levels of attitudes toward environmental issues. Establishment of a reliable Likert scale measurement instrument was accomplished. Permission to use an existing survey was obtained. Additional items were added to increase validity. Establishment of reliability was accomplished through a Guttman split half analysis of the piloted instrument. Through the use of factor analysis, four categories or sub-groupings of attitudes were determined to exist. Reliability was established for the factors. These sub-groupings were identified as personal commitment to environmental protection, awareness of avenues for action, loci of control, and students' perception of teachers' abilities to present environmental topics. These categories were a part of the analysis of four hypotheses.

Assessing the accuracy of globe thermometer method in predicting outdoor mean radiant temperature under Malaysia tropical microclimate

Science.gov (United States)

Khrit, N. G.; Alghoul, M. A.; Sopian, K.; Lahimer, A. A.; Elayeb, O. K.

2017-11-01

Assessing outdoor human thermal comfort and urban climate quality require experimental investigation of microclimatic conditions and their variations in open urban spaces. For this, it is essential to provide quantitative information on air temperature, humidity, wind velocity and mean radiant temperature. These parameters can be quantified directly except mean radiant temperature (Tmrt). The most accurate method to quantify Tmrt is integral radiation measurements (3-D shortwave and long-wave) which require using expensive radiometer instruments. To overcome this limitation the well-known globe thermometer method was suggested to calculate Tmrt. The aim of this study was to assess the possibility of using indoor globe thermometer method in predicting outdoor mean radiant temperature under Malaysia tropical microclimate. Globe thermometer method using small and large sizes of black-painted copper globes (50mm, 150mm) were used to estimate Tmrt and compare it with the reference Tmrt estimated by integral radiation method. The results revealed that the globe thermometer method considerably overestimated Tmrt during the middle of the day and slightly underestimated it in the morning and late evening. The difference between the two methods was obvious when the amount of incoming solar radiation was high. The results also showed that the effect of globe size on the estimated Tmrt is mostly small. Though, the estimated Tmrt by the small globe showed a relatively large amount of scattering caused by rapid changes in radiation and wind speed.

The Significance of Ongoing Teacher Support in Earth Science Education Programs: Evidence from the GLOBE Program

Science.gov (United States)

Penuel, B.; Korbak, C.; Shear, L.

2003-12-01

The GLOBE program provides a rich context for examining issues concerning implementation of inquiry-oriented, scientist-driven educational programs, because the program has both a history of collecting evaluation data on implementation and mechanisms for capturing program activity as it occurs. In this paper, researchers from SRI International's evaluation team explore the different roles that regional partners play in preparing and supporting teachers to implement the GLOBE Program, an international inquiry-based Earth science education initiative that has trained over 14,000 teachers worldwide. GLOBE program evaluation results show the program can be effective in increasing students' inquiry skills, but that the program is also hard for teachers to implement (Means et al., 2001; Penuel et al., 2002). An analysis of GLOBE's regional partner organizations, which are tasked with preparing teachers to implement its data collection and reporting protocols with students, shows that some partners are more successful than others. This paper reports findings from a quantitative analysis of the relationship between data reporting and partner support activities and from case studies of two such regional partners focused on analyzing what makes them successful. The first analysis examined associations between partner training and support activities and data reporting. For this analysis, we used data from the GLOBE Student Data Archive matched with survey data collected from a large sample of GLOBE teachers as part of SRI's Year 5 evaluation of GLOBE. Our analyses point to the central importance of mentoring and material support to teachers. We found that incentives, mentoring, and other on-site support to teachers have a statistically significant association with higher data reporting levels. We also found that at present, teachers access these supports less often than they access listservs and e-mail communication with teachers after GLOBE training. As a follow-up to this

U.S. Decision Making and Post-Cold War NATO Enlargement

Science.gov (United States)

2015-03-01

interactions with one another and by external events. Additionally, enlarging NATO entails modifying the North Atlantic Treaty, which, by constitutional ...III discusses NATO’s second enlargement round, which welcomed Bulgaria, Estonia, Lithuania, Latvia, Romania, Slovakia, and Slovenia into the...membership for Romania and Slovenia , it might give the impression that Russian objections carried weight, discouraging the future pursuit of membership and

“Universe of Particles” opens in the Globe

CERN Multimedia

Carolyn Lee

2010-01-01

CERN’s brand new permanent exhibition provides a high-tech experience with virtual interactive stations and pieces of actual detectors to intrigue the general public about some of the world’s most sophisticated physics tools and experiments.   Universe of Particles exhibition will open on 1 July in the Globe of Science and Technology. Upon entering the dark interior of the Globe, one has a sense of emerging into a portal to the outer universe. Large projections that fill the walls and a 6 m large diameter circle screen in the middle of the ground where space swirls with stars and planets, as well as particle collisions from the LHC experiments. Questions such as where do we come from? What are the laws of Nature? Why did antimatter and matter not destroy each other just after the Big Bang? Will we find particles that make up the mysterious dark matter or the Higgs particle? are linked to the research being done at the LHC. Visitors are invited to explore the unique spherica...

CinéGlobe presents: "One Day on Earth"

CERN Multimedia

2012-01-01

The CinéGlobe International Film Festival is proud to announce that it will be hosting the Swiss edition of the Global Screening of “One Day on Earth”, the first film to be shot and then screened in every country in the world.   Founded in 2008, “One Day on Earth's” first media creation event occurred on 10.10.10. The collaboration was the first ever simultaneous filming event occuring in every country of the world. It created a unique geo-tagged video archive as well as a unique feature film. “One Day on Earth” showcases the amazing diversity, conflict, tragedy, and triumph that occurs in one day on our planet.  This Earth Day, April 22nd, CinéGlobe and CERN invite the public to a free global screening event of the first One Day on Earth Motion Picture. This unique film, created from over 3000 hours of footage, was shot by the One Day on Earth community in every country of the world on October...

The prevalence of incidentally detected adrenal enlargement on CT

International Nuclear Information System (INIS)

Tang, Y.Z.; Bharwani, N.; Micco, M.; Akker, S.; Rockall, A.G.; Sahdev, A.

2014-01-01

Aim: To assess the prevalence and the department's detection rate of adrenocortical hyperplasia. Materials and methods: All computed tomography (CT) examinations of the adrenal glands between February and April 2011 were reviewed. The study excluded patients with known underlying cancer, abdominal trauma, or endocrine disease. The adrenal gland was deemed enlarged if its body was greater than 10 mm diameter, or a limb greater than 5 mm. Results: There were a total of 564 eligible CT studies during this period. A total of 64 cases of incidental adrenal enlargement were found giving a prevalence of 11.3%. Only nine cases were reported in the contemporaneous CT report. Conclusion: The results of the present study show that incidental adrenal enlargement has a significant prevalence. It is often dismissed during reporting, and awareness needs to be raised in the radiological community. Equally, the clinical and biochemical significance needs to be assessed with endocrine correlation

[Transient enlargement of craniopharyngioma cysts after stereotactic radiotherapy and radiosurgery].

Science.gov (United States)

Mazerkina, N A; Savateev, A N; Gorelyshev, S K; Konovalov, A N; Trunin, Yu Yu; Golanov, A V; Medvedeva, O A; Kalinin, P L; Kutin, M A; Astafieva, L I; Krasnova, T S; Ozerova, V I; Serova, N K; Butenko, E I; Strunina, Yu V

Stereotactic radiotherapy/radiosurgery (RT/ES) is an effective technique for treating craniopharyngiomas (CPs). However, enlargement of the cystic part of the tumor occurs in some cases after irradiation. The enlargement may be transient and not require treatment or be a true relapse requiring treatment. In this study, we performed a retrospective analysis of 79 pediatric patients who underwent stereotactic RT or RS after resection of craniopharyngioma. Five-year relapse-free survival after complex treatment of CP was 86%. In the early period after irradiation, 3.5 months (2.7-9.4) on average, enlargement of the cystic component of the tumor was detected in 10 (12.7%) patients; in 9 (11.4%) of them, the enlargement was transient and did not require treatment; in one case, the patient underwent surgery due to reduced visual acuity. In 8 (10.1%) patients, an increase in the residual tumor (a solid component of the tumor in 2 cases and a cystic component of the tumor in 6 cases) occurred in the long-term period after irradiation - after 26.3 months (16.6-48.9) and did not decrease during follow-up in none of the cases, i.e. continued growth of the tumor was diagnosed. A statistical analysis revealed that differences in the terms of transient enlargement and true continued growth were statistically significant (pcraniopharyngioma cyst in the early period (up to 1 year) after RT/RS is usually transient and does not require surgical treatment (except cases where worsening of neurological symptoms occurs, or occlusive hydrocephalus develops).

NATO Enlargement: Balancing Economic and Military Objectives

National Research Council Canada - National Science Library

Bostick, Thomas

1997-01-01

The military requirements of NATO Enlargement should be tied to NATO's overall goal of seeking stability in all of Europe such that it does not undermine political and economic success in new member countries...

A 3D Planetary Neocartographic Tool in Education: A Game on Virtual Moon and Mars Globes

Science.gov (United States)

Hargitai, H.; Simonné-Dombóvári, E.; Gede, M.

2012-03-01

The paper describes the educational use of online virtual globes of Mars and the Moon. The game uses topographic globes of Mars (MOLA) and the Moon (LRO DTM) that includes IAU nomenclature + informal names. Students have to position the points described.

MRI of enlarged dorsal ganglia, lumbar nerve roots, and cranial nerves in polyradiculoneuropathies

International Nuclear Information System (INIS)

Castillo, M.; Mukherji, S.K.

1996-01-01

This paper describes the MRI findings in four patients with a clinical diagnosis of hypertrophic polyradiculoneuropathies. In two examination of the lumbar spine showed enlarged nerve roots and dorsal ganglia, and similar findings were present in the cervical spine in a third. The cisternal portions of the cranial nerves were enlarged in another patient. MRI allows identification of enlarged nerves in hypertrophic polyradiculopathies. (orig.)

Le CERN s'offre un Globe pour séduire le public et les entreprises

CERN Multimedia

Tesnier, Gregory

2004-01-01

The Globe will be open for the public during 2005; a trip that goes from infinitely small to infinitely large will be explained to the visitors at the first floor; exhibitions, conferences and seminars will be also held there and the Globe will be also used for exchanges between CERN and the Industry

The w-categories associated with products of infinite-dimensional globes

International Nuclear Information System (INIS)

Cui, H.

2000-11-01

The results in this thesis are organised in four chapters. Chapter 1 is preliminary. We state the necessary definitions and results in w- complexes, atomic complexes and products of w-complexes. Some definitions are restated to meet the requirement for the following chapters. There is a new proof for the existence of 'natural homomorphism' (Theorem 1.3.6) and a new result for the decomposition of molecules in loop-free w-complexes (Theorem 1.4.13). In Chapter 2, we study the product of three infinite dimensional globes. The main result in this chapter is that a subcomplex in the product of three infinite dimensional globes is a molecule if and only if it is pairwise molecular (Theorem 2.1.6). The definition for pairwise molecular subcomplexes is given in section 1. One direction of the main theorem, molecules are necessarily pairwise molecular, is proved in section 2. Some properties of pairwise molecular subcomplexes are studied in section 3. These properties are the preparation for a more explicit description of pairwise molecular subcomplexes, which is given in section 4. The properties for the sources and targets of pairwise molecular subcomplexes are studied in section 5, where we prove that the class of pairwise molecular subcomplexes is closed under source and target operation; there are also algorithms to calculate the sources and targets of a pairwise molecular subcomplex. Section 6 deals with the composition of pairwise molecular subcomplexes. The proof of the main theorem is completed in section 7, where an algorithm for decomposing molecules into atoms is implied in the proof. The construction of molecules in the product of three infinite dimensional globes is studied in Chapter 3. The main result is that any molecule can be constructed inductively by a systematic approach. Section 1 gives another description for molecules in the product of three infinite dimensional globes which is the theoretical basis for the construction. Section 2 states the

Salivary gland enlargement during oesophageal stricture dilatation.

OpenAIRE

Martin, D.

1980-01-01

A case of recurrent salivary gland enlargement occurring during fibreoptic oesophagoscopy and oesophageal stricture dilatation with Eder-Puestow dilators is described. The genesis of this condition is discussed and its transient and usually benign nature emphasized.

Body-enlarging effect of royal jelly in a non-holometabolous insect species, Gryllus bimaculatus

Directory of Open Access Journals (Sweden)

Atsushi Miyashita

2016-06-01

Full Text Available Honeybee royal jelly is reported to have body-enlarging effects in holometabolous insects such as the honeybee, fly and silkmoth, but its effect in non-holometabolous insect species has not yet been examined. The present study confirmed the body-enlarging effect in silkmoths fed an artificial diet instead of mulberry leaves used in the previous literature. Administration of honeybee royal jelly to silkmoth from early larval stage increased the size of female pupae and adult moths, but not larvae (at the late larval stage or male pupae. We further examined the body-enlarging effect of royal jelly in a non-holometabolous species, the two-spotted cricket Gryllus bimaculatus, which belongs to the evolutionarily primitive group Polyneoptera. Administration of royal jelly to G. bimaculatus from its early nymph stage enlarged both males and females at the mid-nymph and adult stages. In the cricket, the body parts were uniformly enlarged in both males and females; whereas the enlarged female silkmoths had swollen abdomens. Administration of royal jelly increased the number, but not the size, of eggs loaded in the abdomen of silkmoth females. In addition, fat body cells were enlarged by royal jelly in the silkmoth, but not in the cricket. These findings suggest that the body-enlarging effect of royal jelly is common in non-holometabolous species, G. bimaculatus, but it acts in a different manner than in holometabolous species.

Comparison of classical dermatoscopy and acrylic globe magnifier dermatoscopy

DEFF Research Database (Denmark)

Lorentzen, Henrik F; Eefsen, Rikke Løvendahl; Weismann, Kaare

2008-01-01

Dermatoscopic asymmetry of melanocytic skin lesion is pivotal in most algorithms assessing the probability of melanoma. Larger lesions cannot be assessed by dermatoscopy and the Dermaphot in a single field of vision, but this can be performed using the acrylic globe magnifier. We examined the dia...

The fifth wave of the European Union enlargement: pro et contra

Directory of Open Access Journals (Sweden)

Batorshina Irina

2011-09-01

Full Text Available This article analyses the principal complex of economic and political motivations of the states of Central and Eastern Europe and the EU members related to the EU enlargement towards the East. Special attention is paid to the discussion on the reasonableness of the EU enlargement and the positions of certain EU members.

The Globe of Science and Innovation's central vortex

CERN Multimedia

Patrice Loiez

2004-01-01

The central vortex of the Globe of Science and Innovation is a crown measuring 6.15 m in diameter and 4.5 m in height. Having been lifted by a crane to a height of over 22 m, the vortex is placed on a support structure which will be removed once the 36 arcs providing the building's structure have been secured in place.

Google Earth: A Virtual Globe for Elementary Geography

Science.gov (United States)

Britt, Judy; LaFontaine, Gus

2009-01-01

Originally called Earth Viewer in 2004, Google Earth was the first virtual globe easily available to the ordinary user of the Internet. Google Earth, at earth.google.com, is a free, 3-dimensional computer model of Earth, but that means more than just a large collection of pretty pictures. It allows the viewer to "fly" anywhere on Earth "to view…

Severe Gingival Enlargement with Coexisting Erosive Lichen Planus in Severe Chronic Periodontitis Patient

Directory of Open Access Journals (Sweden)

Ambika Sharma

2015-01-01

Full Text Available Plaque induced gingival enlargement is most commonly seen and when encountered simultaneously with erosive lichen planus poses a challenge to the treating dentist. Prognosis of one condition may influence the prognosis of another condition. The presented case highlights the significance of proper diagnosis and the management of simultaneously occurring gingival lesions. A 49-year-old hypertensive female presented with painful enlarged bleeding and suppurating gums with burning sensation on eating food along with long-term usage of antihypertensive drug amlodipine known for its gingival enlargement effect. All these multiple factors led to diagnostic dilemma. Effective management of the gingival enlargement was done by using electrocautery to rehabilitate the functions and esthetics of the patient. Gingival condition was also complicated by the presence of coexisting lichen planus which was predominantly erosive for which topical corticosteroid, antifungal, and antimicrobial agents were prescribed. Eight-month follow-up did not show recurrence of gingival enlargement. Electrocautery is an effective tool for the gingivectomy in severe inflammatory type of gingival enlargement because of rapid postoperative hemostasis. For the management of erosive lichen planus, long-term use of topical corticosteroids is an effective approach. Maintenance of oral hygiene and regular follow-ups are essential for these conditions.

Aerial drone misadventure: A novel case of trauma resulting in ocular globe rupture

Directory of Open Access Journals (Sweden)

Eliza E. Moskowitz

2018-06-01

Full Text Available Purpose: The purpose of this case report is to present the novel findings of a drone causing such a traumatic ocular injury and provide recommendations for how it might be prevented. Observations: We report on a recent case where a child presented to our Emergency Department after incurring a blow to the face by the propeller of a remote controlled drone. The patient suffered significant trauma including rupture of the right globe. Conclusions: As drone sales continue to rise, it is important that physicians be prepared to treat the potential injuries that may result from using these devices. Furthermore, in an attempt to reduce the number of visits associated with remote controlled drones, physicians should be prepared to provide advice as to how patients can reduce the risks of injury. Importance: We hope that the framework and recommendations below will help physicians decrease adverse outcomes related to this unusual injury pattern. Keywords: Drone, Trauma, Globe injury, Globe rupture, Ocular trauma, Corneal trauma, Scleral trauma

GLOBE at Night: Raising Public Awareness and Involvement through Citizen Science

Science.gov (United States)

Walker, C. E.; Pompea, S. M.; Sparks, R. T.

2010-12-01

With half of the world’s population now living in cities, many urban dwellers have never experienced the wonderment of pristinely dark skies and maybe never will. Light pollution is obscuring people’s long-standing natural heritage to view stars. The GLOBE at Night program (www.globeatnight.org) is an international citizen-science campaign to raise public awareness of the impact of light pollution by encouraging everyone everywhere to measure local levels of night sky brightness and contribute observations online to a world map. In the last 5 years, GLOBE at Night has been the most productive public light pollution monitoring campaign, collecting over 52,000 observations in a two-week period annually. This year, during the moonless two weeks in March, the campaign set a record high of over 17,800 measurements from people in 86 countries. Foundational resources are available to facilitate the public’s participation in promoting dark skies awareness. The GLOBE at Night website explains clearly the simple-to-participate-in 5 step program and offers background information and interactive games on key concepts. The program has been expanded to include trainings of the general public, but especially educators in schools, museums and science centers, in unique ways. Education kits for dark skies awareness have been distributed at the training workshops. The kit includes material for a light shielding demonstration, a digital Sky Quality Meter and “Dark Skies Rangers” activities. The activities are on how unshielded light wastes energy, how light pollution affects wildlife and how you can participate in a citizen-science star-hunt like GLOBE at Night. In addition, projects are being developed for what to do with the data once it is taken. The GLOBE at Night data from different years can be compared to look for trends over time or with population density maps. The data can also be used to search for dark sky oases or to monitor lighting ordinance compliance. Most

Tilt, Decentration, and Internal Higher-Order Aberrations of Sutured Posterior-Chamber Intraocular Lenses in Patients with Open Globe Injuries

Directory of Open Access Journals (Sweden)

Xiangjia Zhu

2017-01-01

Full Text Available Purpose. To evaluate the tilt, decentration, and internal higher-order aberrations (HOAs of sutured posterior-chamber intraocular lenses (IOLs in patients with open globe injuries. Methods. 46 consecutive patients (47 eyes who underwent transsclerally sutured IOL implantation were enrolled in this prospective cohort study. Nineteen eyes had a history of open globe injury. The tilt and decentration of the IOLs and the visual quality were measured 1 month after surgery. Results. The horizontal tilt and decentration of the IOLs in the open-globe-injury group were significantly higher than those in the control group (both P<0.05. In the open-globe-injury group, the horizontal decentration was significantly greater in the limbus-sclera-involved group (n=11 than in the only-cornea-involved group (n=8, P=0.040. The internal coma, 3rd-order, and total HOA values at pupil sizes of 4 mm (P=0.006 and 6 mm (P=0.013 were significantly higher in the open-globe-injury group than in the controls. Consequently, the optical quality data for the modulation transfer function and the Strehl ratio (all P<0.05 were significantly poorer in the open-globe-injury group. Conclusions. Open globe injuries damage the structural integrity of the eyeball, resulting in more-misaligned sutured IOLs and poorer visual quality.

Western Balkan States and the European Union Enlargement

Directory of Open Access Journals (Sweden)

Gelina Maliqi (Ramolli

2011-07-01

Full Text Available For half a century, European Union-(EU has pursued ever-deeper integration while taking in new members. It’s marked as an important step in relationship deepening between EU and Western Balkans-(WBs where Albania is part of. In 2003, EU declared that the future of WBs is within EU. Initially it adopted a generous strategy that linked the timetable for accession to the pace of reform in WBs. The declaration contained a conditional promise; EU would consider WBs for membership only if they reached EU standards. The EU was motivated by usual economic considerations connected to enlargement and a desire to increase regional stability. The enlargement process regarding Albania will bring several reforms on different fields. Our country will benefit from a share of multibeneficiary funds for competitiveness, SMEs, energy efficiency and banking sector regulation. This presentation handles out these main issues: EU policy and the enlargement process regarding Albania inspecting the way and progress done up to now by our country, the main features of our national EUcoordination system, concluding in a SWOT Analysis of EU-coordination system in Albania. Eventually, I believe that Albania being part of WBs is at one time an opportunity and a challenge for the future of EU.

An Arduino Based Citizen Science Soil Moisture Sensor in Support of SMAP and GLOBE

Science.gov (United States)

Podest, E.; Das, N. N.; Rajasekaran, E.; Jeyaram, R.; Lohrli, C.; Hovhannesian, H.; Fairbanks, G.

2017-12-01

Citizen science allows individuals anywhere in the world to engage in science by collecting environmental variables. One of the longest running platforms for the collection of in situ variables is the GLOBE program, which is international in scope and encourages students and citizen scientists alike to collect in situ measurements. NASA's Soil Moisture Active Passive (SMAP) satellite mission, which has been acquiring global soil moisture measurements every 3 days of the top 5 cm of the soil since 2015, has partnered with the GLOBE program to engage students from around the world to collect in situ soil moisture and help validate SMAP measurements. The current GLOBE SMAP soil moisture protocol consists in collecting a soil sample, weighing, drying and weighing it again in order to determine the amount of water in the soil. Preparation and soil sample collection can take up to 20 minutes and drying can take up to 3 days. We have hence developed a soil moisture measurement device based on Arduino- microcontrollers along with off-the-shelf and homemade sensors that are accurate, robust, inexpensive and quick and easy to use so that they can be implemented by the GLOBE community and citizen scientists alike. In addition, we have developed a phone app, which interfaces with the Arduino, displays the soil moisture value and send the measurement to the GLOBE database. This talk will discuss building, calibration and validation of the soil moisture measuring device and assessing the quality of the measurements collected. This work was carried out at the Jet Propulsion Laboratory, California Institute of Technology, under contract with the National Aeronautics and Space Administration.

Salivary gland enlargement during oesophageal stricture dilatation.

Science.gov (United States)

Martin, D.

1980-01-01

A case of recurrent salivary gland enlargement occurring during fibreoptic oesophagoscopy and oesophageal stricture dilatation with Eder-Puestow dilators is described. The genesis of this condition is discussed and its transient and usually benign nature emphasized. Images Fig. 1 PMID:7393809

Tumescent power liposuction in the treatment of the enlarged male breast.

Science.gov (United States)

Boni, Roland

2006-01-01

Tumescent power liposuction is widely used on various parts of the body for minimal-access lipectomy. The undesired fat deposits are injected with tumescence fluid containing saline, epinephrine, bicarbonate and lidocaine; the latter is used as the only source of pain control. The fat is then removed using vibrating microcannulas. To evaluate the value of tumescent power liposuction in the treatment of the enlarged male breast. 38 male patients aged 23-64 years (mean age 39.8 +/- 9.7 years) with enlarged breasts were enrolled in the study. In 32 patients, breasts were enlarged due to fat tissue, and the ductal glands were not palpable (pseudogynecomastia). In 6 patients, the ductal glands were enlarged (gynecomastia). All patients were treated with tumescent liposuction over a 2-year period using a single entry site from the axillary fossa. Both fat as well as ductal and stromal tissue were removed by microcannulas. None of the patients had early postoperative complications of infection, hematoma or seroma. There were no treatment-induced asymmetries, contour deformities or irregularities. No open excision or skin reduction procedures were required. Tumescent liposuction using a single entry site in the axillary fossa is a minimally invasive technique to treat enlarged male breasts. Both fat (pseudogynecomastia in adipose patients) as well as ductal and stromal tissue (in gynecomastia) can be removed with tumescent liposuction, resulting in a high level of patient satisfaction. Copyright 2006 S. Karger AG, Basel.

Relationship between intracranial internal carotid artery calcification and enlarged cerebral perivascular space

Energy Technology Data Exchange (ETDEWEB)

Tao, Xiao-Xiao [Shanghai Ninth People' s Hospital, Shanghai Jiao Tong University School of Medicine, Department of Neurology, Shanghai (China); The First People' s Hospital of Wenling, Department of Neurology, Wenling (China); Li, Ge-Fei; Wu, Yi-Lan; Liu, Yi-Sheng; Zhao, Ying; Shi, Yan-Hui; Zhuang, Mei-Ting; Hou, Tian-Yu; Zhao, Rong; Liu, Feng-Di; Wang, Xue-Mei; Shen, Ying; Cui, Guo-Hong; Su, Jing-Jing; Chen, Wei [Shanghai Ninth People' s Hospital, Shanghai Jiao Tong University School of Medicine, Department of Neurology, Shanghai (China); Tang, Xue-Mei; Sun, Ji; Liu, Jian-Ren [Shanghai Ninth People' s Hospital, Shanghai Jiao Tong University School of Medicine, Department of Neurology, Shanghai (China); Shanghai Jiao Tong University School of Medicine, Clinical Research Center, Shanghai (China)

2017-06-15

The association between intracranial internal carotid artery (IICA) calcification and lacunes, white matter hyperintensity (WMH), and cerebral microbleeds (CMBs) has been well researched. However, enlarged cerebral perivascular space (PVS) has not yet been reported to correlate with intracranial internal carotid artery calcification. Therefore, the primary aim of this study was to investigate the relationship between IICA calcification and enlarged PVS. A total of 189 patients with ischemic stroke in the middle cerebral artery territory who presented within 7 days of ictus from 2012 to 2015 were enrolled respectively. All patients were required to have undergone head computed tomography, magnetic resonance imaging, susceptibility-weighted magnetic resonance imaging, magnetic resonance angiography, or computed tomography angiography. Clinical characteristics were recorded. IICA calcification and enlarged PVS were semi-quantitatively evaluated, and the presence of lacunes, WMH, and CMBs was recorded. Of the 189 patients, 63.5% were male. Mean age of the patients was 68.6 ± 12.2 years. There were 104 patients with IICA calcification. Age, diabetes mellitus, lacunes, and white matter hyperintensity were significantly associated with IICA calcification (P < 0.05). Multivariate logistic regression analysis showed that age, diabetes mellitus, and lacunes were independent predictors of IICA calcification (P < 0.05). A lower risk of IICA calcification was found in patients with a higher enlarged PVS score (P = 0.004). Higher enlarged PVS scores were associated with a lesser degree of IICA calcification. There appears to be a relationship between reduced risk of IICA calcification and enlarged PVS. (orig.)

The power of Virtual Globes for valorising cultural heritage and enabling sustainable tourism: NASA World Wind applications

Science.gov (United States)

Brovelli, M.; Hogan, P.; Minghini, M.; Zamboni, G.

2013-10-01

Inspired by the visionary idea of Digital Earth, as well as from the tremendous improvements in geo-technologies, use of virtual globes has been changing the way people approach to geographic information on the Web. Unlike the traditional 2D-visualization typical of Geographic Information Systems (GIS), virtual globes offer multi-dimensional, fully-realistic content visualization which allows for a much richer user experience. This research investigates the potential for using virtual globes to foster tourism and enhance cultural heritage. The paper first outlines the state of the art for existing virtual globes, pointing out some possible categorizations according to license type, platform-dependence, application type, default layers, functionalities and freedom of customization. Based on this analysis, the NASA World Wind virtual globe is the preferred tool for promoting tourism and cultural heritage. This is because its open source nature allows unlimited customization (in terms of both data and functionalities), and its Java core supports platform-independence. Relevant tourism-oriented World Wind-based applications, dealing with both the Web promotion of historical cartography and the setup of a participatory Web platform exploiting crowd-sourced data, are described. Finally, the paper presents a project focusing on the promotion of the Via Regina area (crossing the border between Italy and Switzerland) through an ad hoc World Wind customization. World Wind can thus be considered an ideal virtual globe for tourism applications, as it can be shaped to increase awareness of cultural history and, in turn, enhance touristic experience.

The Globe. Neighbourhood Agenda 21: Going Local in Reading.

Science.gov (United States)

Welsh, Richard

1994-01-01

Reports on the philosophy underlying a project to promote local community involvement in neighborhood plans as a basis for a citywide Local Agenda 21 and the first stages of Go Local on a Better Environment (GLOBE) introduced to give the project a popular identify and communicate the environmental message. (LZ)

Peculiar enlargement of the nasopharynx in patients with anorexia nervosa

Energy Technology Data Exchange (ETDEWEB)

Okamoto, K. [Department of Radiology, School of Dentistry, Niigata Univ. (Japan); Ito, J. [Department of Radiology, School of Dentistry, Niigata Univ. (Japan); Tokiguchi, S. [Department of Radiology, School of Dentistry, Niigata Univ. (Japan); Kuwabara, G. [Department of Radiology, School of Medicine, Niigata University, Niigata (Japan); Nishihara, M. [Department of Radiology, School of Medicine, Niigata University, Niigata (Japan)

1995-11-01

We examined the nasopharynx and brain in 17 patients with anorexia nervosa by CT and compared the findings with those of 44 normal subjects and of 5 patients of the same age with marked emaciation caused by various psychiatric disorders. An enlarged nasopharyngeal space with a flattened posterior wall and enlarged lateral pharyngeal recesses were demonstrated in all patients with anorexia nervosa whose weight was lowest at the time of the CT examination, and these CT features regressed or became normal quickly after they had gained some weight. This characteristic enlargement of the nasopharynx and lateral pharyngeal recesses was observed neither in the markedly emaciated patients (2 with schizophrenia, 1 with major depression, 1 with stupor and the other with an extremely unbalanced diet) nor in 44 normal subjects without emaciation. These features were therefore thought to be characteristic and of diagnostic significance. (orig.). With 5 figs., 3 tabs.

Peculiar enlargement of the nasopharynx in patients with anorexia nervosa

International Nuclear Information System (INIS)

Okamoto, K.; Ito, J.; Tokiguchi, S.; Kuwabara, G.; Nishihara, M.

1995-01-01

We examined the nasopharynx and brain in 17 patients with anorexia nervosa by CT and compared the findings with those of 44 normal subjects and of 5 patients of the same age with marked emaciation caused by various psychiatric disorders. An enlarged nasopharyngeal space with a flattened posterior wall and enlarged lateral pharyngeal recesses were demonstrated in all patients with anorexia nervosa whose weight was lowest at the time of the CT examination, and these CT features regressed or became normal quickly after they had gained some weight. This characteristic enlargement of the nasopharynx and lateral pharyngeal recesses was observed neither in the markedly emaciated patients (2 with schizophrenia, 1 with major depression, 1 with stupor and the other with an extremely unbalanced diet) nor in 44 normal subjects without emaciation. These features were therefore thought to be characteristic and of diagnostic significance. (orig.). With 5 figs., 3 tabs

A rapidly enlarging cutaneous hemangioma in pregnancy.

LENUS (Irish Health Repository)

Ma'ayeh, Marwan

2014-06-18

This is a case of a rapidly enlarging cutaneous pedunculated tumor on a patient\\'s thumb during her pregnancy. This was excised and identified as a hemangioma. A literature search identified a possible hormonal factor in causing an accelerated growth of this tumor.

Gingival enlargement unveiling sarcoidosis: Report of a rare case

Directory of Open Access Journals (Sweden)

Sabeeha Abbas Kadiwala

2013-01-01

Full Text Available Sarcoidosis is classified as an acquired systemic granulomatous disease. Because of the fact that sarcoidosis affects multiple tissues and organs, it is characterized by many potential signs and symptoms, as well as by the presence of non-caseating granulomas in the organs involved. Although oral sarcoidosis is relatively rare, it may however, present in the oral cavity. This report presents a rare case of sarcoidosis with the initial presenting symptom as severe generalized gingival enlargement. The gingival enlargement was treated by gingivectomy. After histopathological examination of gingival biopsy and certain special investigations, a diagnosis of sarcoidosis was made.

Humane Orientation as a New Cultural Dimension of the GLOBE Project

DEFF Research Database (Denmark)

Schlösser, Oliver; Frese, Michael; Heintze, Anna-Maria

2013-01-01

We validate, extend, and empirically and theoretically criticize the cultural dimension of humane orientation of the project GLOBE (Global Leadership and Organizational Behavior Effectiveness Research Program). Theoretically, humane orientation is not just a one-dimensionally positive concept about...... study used student samples from 25 countries that were either high or low in humane orientation (N = 876) and studied their relation to the traditional GLOBE scale and other cultural-level measures (agreeableness, religiosity, authoritarianism, and welfare state score). Findings revealed a strong...... correlation between humane orientation and agreeableness, welfare state score, and religiosity. Out-group humane orientation proved to be the more relevant subfacet of the original humane orientation construct, suggesting that future research on humane orientation should make use of this measure instead...

Aortic Root Enlargement or Sutureless Valve Implantation?

Directory of Open Access Journals (Sweden)

Nikolaos G. Baikoussis

2016-11-01

Full Text Available Aortic valve replacement (AVR in patients with a small aortic annulus is a challenging issue. The importance of prosthesis–patient mismatch (PPM post aortic valve replacement (AVR is controversial but has to be avoided. Many studies support the fact that PPM has a negative impact on short and long term survival. In order to avoid PPM, aortic root enlargement may be performed. Alternatively and keeping in mind that often some comorbidities are present in old patients with small aortic root, the Perceval S suturelles valve implantation could be a perfect solution. The Perceval sutureless bioprosthesis provides reasonable hemodynamic performance avoiding the PPM and providing the maximum of aortic orifice area. We would like to see in the near future the role of the aortic root enlargement techniques in the era of surgical implantation of the sutureless valve (SAVR and the transcatheter valve implantation (TAVI.

Orbital Blowout Fracture with Complete Dislocation of the Globe into the Maxillary Sinus.

Science.gov (United States)

Wang, Joy Mh; Fries, Fabian N; Hendrix, Philipp; Brinker, Titus; Loukas, Marios; Tubbs, R Shane

2017-09-29

This rare case report describes the diagnosis and treatment of an isolated left-sided orbital floor fracture with a complete dislocation of the globe into the maxillary sinus and briefly discusses the indications of surgery and recovery for orbital floor fractures in general. Complete herniation of the globe through an orbital blow-out fracture is uncommon. However, the current case illustrates that such an occurrence should be in the differential diagnosis and should be considered, especially following high speed/impact injuries involving a foreign object. In these rare cases, surgical intervention is required.

Morphological analysis of enlarged ventricle on CT image, using multivariate analysis

International Nuclear Information System (INIS)

Iwasaki, Satoru; Kichikawa, Kimihiko; Otsuji, Hideyuki; Fukusumi, Akio; Kobayashi, Yasuo.

1983-01-01

Multivariate analysis of enlarged cerebral ventricle on CT was undertaken to study the characteristics of ventricular morphology. Several ventricular segments of enlarged ventricle, defined on the basis of the study of normal group, were linearly measured on CT image. Then the discriminant analysis with the increase and decrease of variable was applied. The following are the results obtained. The error ratio of discrimination between pressure hydrocephalus and cerebral atrophy was 8.4 %, and between obstructive hydrocephalus and communicating hydrocephalus was 11.3 %. Ventricular segments were divided into three groups according to their character of enlargement: (1) the temporal horn and trigone are large in pressure hydrocephalus; (2) the hypothalamic segment of the third ventricle and the body of lateral ventricle are larger in obstructive hydrocephalus than in communicating hydrocephalus; (3) the anterior horn, cellae mediae at the level of the head of caudate nuclei and thalamic segment of the third ventricle are relatively large in cerebral atrophy and communicating hydrocephalus. The hypothalamic segment of the third ventricle assumes a round or oval shape in pressure hydrocephalus but a rectangular or teardrop shape in cerebral atrophy. These findings are contributory to pathological evaluation of ventricular enlargement. (author)

In Vitro Callogenesis and Agrobacterium-Mediated Transformation of Globe Artichoke

NARCIS (Netherlands)

Menin, B.; Moglia, A.; Comino, C.; Lanteri, S.; Herpen, van T.W.J.M.; Beekwilder, M.J.

2012-01-01

Micropropagation techniques have been widely applied in globe artichoke (C. cardunculus L. var. scolymus), however, efficient protocols for the establishment of in vitro callogenesis and organogenesis, a pre-requisite for Agrobacterium-mediated genetic transformation, have not been set up so far. We

Red Ginseng Extract Attenuates Kainate-Induced Excitotoxicity by Antioxidative Effects

Directory of Open Access Journals (Sweden)

Jin-Yi Han

2012-01-01

Full Text Available This study investigated the neuroprotective activity of red ginseng extract (RGE, Panax ginseng, C. A. Meyer against kainic acid- (KA- induced excitotoxicity in vitro and in vivo. In hippocampal cells, RGE inhibited KA-induced excitotoxicity in a dose-dependent manner as measured by the MTT assay. To study the possible mechanisms of the RGE-mediated neuroprotective effect against KA-induced cytotoxicity, we examined the levels of intracellular reactive oxygen species (ROS and [Ca2+]i in cultured hippocampal neurons and found that RGE treatment dose-dependently inhibited intracellular ROS and [Ca2+]i elevation. Oral administration of RGE (30 and 200 mg/kg in mice decreased the malondialdehyde (MDA level induced by KA injection (30 mg/kg, i.p.. In addition, similar results were obtained after pretreatment with the radical scavengers Trolox and N, N′-dimethylthiourea (DMTU. Finally, after confirming the protective effect of RGE on hippocampal brain-derived neurotropic factor (BDNF protein levels, we found that RGE is active compounds mixture in KA-induced hippocampal mossy-fiber function improvement. Furthermore, RGE eliminated 1,1-diphenyl-2-picrylhydrazyl (DPPH radicals, and the IC50 was approximately 10 mg/ml. The reductive activity of RGE, as measured by reaction with hydroxyl radical (•OH, was similar to trolox. The second-order rate constant of RGE for •OH was 3.5–4.5×109 M−1·S−1. Therefore, these results indicate that RGE possesses radical reduction activity and alleviates KA-induced excitotoxicity by quenching ROS in hippocampal neurons.

Inauguration of the Globe of Science and Innovation

CERN Multimedia

Patrice Loiez; Michel Blanc

2004-01-01

The building formerly known as 'Palais de l'Equilibre' has been given to CERN by the Swiss Confederation to mark the Laboratory's 50th Anniversary. The impressive 28 m high, 40 m diameter sphere was built by a consortium of 11 Swiss companies who specialise in timber construction. The Globe is a symbol for sustainable development: it is constructed entirely from wood and its circular form represents planet Earth.

Construction of a reference molecular linkage map of globe artichoke (Cynara cardunculus var. scolymus).

Science.gov (United States)

Portis, E; Mauromicale, G; Mauro, R; Acquadro, A; Scaglione, D; Lanteri, S

2009-12-01

The genome organization of globe artichoke (Cynara cardunculus var. scolymus), unlike other species belonging to Asteraceae (=Compositae) family (i.e. sunflower, lettuce and chicory), remains largely unexplored. The species is highly heterozygous and suffers marked inbreeding depression when forced to self-fertilize. Thus a two-way pseudo-testcross represents the optimal strategy for linkage analysis. Here, we report linkage maps based on the progeny of a cross between globe artichoke (C. cardunculus var. scolymus) and cultivated cardoon (C. cardunculus var. altilis). The population was genotyped using a variety of PCR-based marker platforms, resulting in the identification of 708 testcross markers suitable for map construction. The male map consisted of 177 loci arranged in 17 major linkage groups, spanning 1,015.5 cM, while female map was built with 326 loci arranged into 20 major linkage groups, spanning 1,486.8 cM. The presence of 84 loci shared between these maps and those previously developed from a cross within globe artichoke allowed for map alignment and the definition of 17 homologous linkage groups, corresponding to the haploid number of the species. This will provide a favourable property for QTL scanning; furthermore, as 25 mapped markers (8%) correspond to coding regions, it has an additional value as functional map and might represent an important genetic tool for candidate gene studies in globe artichoke.

Clinical biochemistry and MRI follow up study in postpartum pituitary enlargement

International Nuclear Information System (INIS)

Chen Weipeng; Huang Shaoqiang; Lu Xiaofan; Cai Baimang; Liu Xuguang

2004-01-01

Objective: To investigate the relationship between enlargement of pituitary in postpartum females and the clinical biochemistry. Methods: In total 6 postpartum women were studied by MRI of pituitary and clinical biochemistry assessment, the data was collected especially in puerperium period. Results: Enlargement of pituitary gland was most remarkable in the first week of puerperium period, while endocrine changes including HCG, Progesterone, E 2 also reached considerable high peak in the same time especially the first and second day after labor. Prolactin also increased. βHCG, Progesterone, and E 2 rapidly decreased after the first week of puerperium period and the size of pituitary gland recovered to normal size. Conclusion: Postpartum enlargement of pituitary gland is physiological and related with internal environment change in gravitation, which is not to be misdiagnosed as a lesion

Closed chamber globe stabilization and needle capsulorhexis using irrigation hand piece of bimanual irrigation and aspiration system

Directory of Open Access Journals (Sweden)

Rai Harminder K

2005-08-01

Full Text Available Abstract Background The prerequisites for a good capsulorhexis include a deep, well maintained anterior chamber, globe stabilization and globe manipulation. This helps to achieve a capsulorhexis of optimal size, shape and obtain the best possible position for a red glow under retroillumination. We report the use of irrigation handpiece of bimanual irrigation aspiration system to stabilize the globe, maintain a deep anterior chamber and manipulate the globe to a position of optimal red reflex during needle capsulorhexis in phacoemulsification. Methods Two side ports are made with 20 G MVR 'V' lance knife (Alcon, USA. The irrigation handpiece with irrigation on is introduced into the anterior chamber through one side port and the 26-G cystitome (made from 26-G needle is introduced through the other. The capsolurhexis is completed with the needle. Results Needle capsulorhexis with this technique was used in 30 cases of uncomplicated immature senile cataracts. 10 cases were done under peribulbar anaesthesia and 20 under topical anaesthesia. A complete capsulorhexis was achieved in all cases. Conclusion The irrigating handpiece maintains deep anterior chamber, stabilizes the globe, facilitates pupillary dilatation, and helps in maintaining the eye in the position with optimal red reflex during needle capsulorhexis. This technique is a safe and effective way to perform needle capsulorhexis.

The analysis of initial cranial CT of early hematoma enlargement in spontaneous intracerebral hemorrhage

OpenAIRE

BEI Yu-zhang; CHEN Ben-yang; QI Hao-bo; ZHOU Zheng-ping; LI Yu-bo

2012-01-01

Objective To investigate the predictive effect of initial cranial CT on early hematoma enlargement in spontaneous intracerebral hemorrhage. Methods Three hundred patients with spontaneous intracerebral hemorrhage within 6 hours after onset were studied. Chi-square test and logistic regression analysis were used to detect the related factors which may indicate hematoma enlargement. Results Sixty-one (20.33% ) patients presented hematoma enlargement on cranial CT. Single factor and multivariate...

Penis enlargement: complication of lipotransfer

OpenAIRE

Conde, C.G.; Soria, J.H.; Orduna, O.D.; Alcoba, E.

2012-01-01

La solicitud de engrosamiento del pene por parte de los pacientes tiene un crecimiento sostenido. El empleo de grasa autóloga como relleno puede causar una deformidad que provoca un menoscabo funcional y estético. Presentamos un caso de complicación que requirió de tratamiento quirúrgico.Penis enlargement is a practice widely requested by the patients. The use of autologous fat transplantation can produce deformity and functional and aesthetic deficiency. The authors present a clinical case o...

Chest CT findings in EBUS-TBNA-proven anthracosis in enlarged mediastinal lymph nodes

Energy Technology Data Exchange (ETDEWEB)

Kirchner, J. [Allgemeines Krankenhaus Hagen (Germany). Dept. of Interventional and Diagnostic Radiology; Mueller, P. [Allgemeines Krankenhaus Hagen (Germany). Dept. of Medicine; Broll, M.; Kirchner, E.M. [Sana Klinikum Duisburg (Germany). Dept. of Medicine; Pomjanski, N.; Biesterfeld, S. [University Hospital Duesseldorf (Germany). Dept. of Pathology; Liermann, D. [Marien Hospital, Herne (Germany). Dept. of Diagnostic and Interventional Radiology and Nuclear Medicine; Kickuth, R. [University Hospital Wuerzburg (Germany). Dept. of Radiology

2014-12-15

We demonstrate the multislice computed tomography (MSCT) findings of endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA)-proven hilar and mediastinal lymph node enlargement with signs of anthracosis. 53 enlarged lymph nodes in 39 patients (28 male, 11 female) with EBUS-TBNA-confirmed anthracosis were analyzed retrospectively. The mean short axis diameter of the enlarged lymph nodes with signs of anthracosis was 13.7 mm. Lymph nodes most often showed an oval shape (84%) and were well defined in 66% of cases. Lymph node confluence was observed in 32% of cases. Calcifications were documented in 24.5% of cases. Contrast enhancement and fatty involution were seen seldom (3.8%). Lymph node necrosis was not seen. Lymph node anthracosis may be found most often in enlarged, well defined lymph nodes with an oval shape, frequently associated with confluence and calcifications.

Role of radionuclide studies in cases of enlarged prostate

International Nuclear Information System (INIS)

Singhvi, S.D.; Shrimali, R.; Singhal, N.C.

1985-01-01

The present study of radionuclide 131 I hyppuran in 30 positive cases of enlarged prostate and 10 normal subjects has been found effective in giving information about functional status of the kidneys and presence of obstructive unropathy by renography, enlargement of the prostate causing bladder base contour deformity in bladder scan and the presence of residual urine by external counting method over bladder. It is a non-invasive method of investigation and can be undertaken safely in cases sensitive iodine-containing contrast medium. It is also cheap, easy to perform and does not require any pre-examination preparation and can be repeated frequently. (author)

Ülevaade GLOBE'i programmi tööst Eestis / Imbi Henno

Index Scriptorium Estoniae

Henno, Imbi

2001-01-01

GLOBE (Global Learning and Observations to Benefit Environment) on üldhariduskoolidele mõeldud keskkonnasuunitlusega haridus- ja teadusprogramm, mis ühendab lapsi, õpetajaid ja teadlasi kogu maailmast

CT screening for lung cancer: Frequency of enlarged adrenal glands identified in baseline and annual repeat rounds

Energy Technology Data Exchange (ETDEWEB)

Hu, Minxia [Icahn School of Medicine at Mount Sinai, Department of Radiology, New York, NY (United States); Capital Medical University, Department of Diagnostic Ultrasound, Beijing Tongren Hospital, Beijing (China); Yip, Rowena; Yankelevitz, David Y.; Henschke, Claudia I. [Icahn School of Medicine at Mount Sinai, Department of Radiology, New York, NY (United States)

2016-12-15

To determine the frequency of adrenal enlargement of participants in a CT-screening program for lung cancer and demonstrate the progression during follow-up, separately for baseline and annual repeat rounds. HIPAA-compliant informed consent was obtained in 4,776 participants. The adrenal gland was defined as enlarged if it measured ≥6 mm at its largest diameter. Logistic regression analyses were performed. At baseline, 202 (4 %) of 4,776 participants had adrenal enlargement. Significant factors were age (OR = 1.4, 95 % CI: 1.2-1.7) and current smoker (OR = 1.8, 95 % CI: 1.3-2.4). Follow-up 7-18 months after baseline for 133 cases with adrenal enlargement <40 mm showed it decreased or was stable in 85 (64 %), and increased by <10 mm in 48 (36 %). Five (0.04 %) cases of adrenal enlargement were newly identified, none increased beyond 40 mm on follow-up. Adrenal enlargement was a significant predictor of a subsequent diagnosis of lung cancer (OR = 2.0, 95 % CI: 1.2-3.4). Participants with adrenal enlargement <40 mm identified at baseline and on repeat screening could be reasonably assessed on subsequent annual screening. Adrenal enlargement increased with increasing pack-years of smoking. Adrenal enlargement was an independent predictor of a subsequent diagnosis of lung cancer. (orig.)

Demographic Characteristics and Clinical Outcome of Work-related Open Globe Injuries in the Most Industrialised Region of Turkey

Directory of Open Access Journals (Sweden)

Sertaç Argun Kıvanç

2017-01-01

Full Text Available Objectives: To evaluate demographic characteristics and clinical outcomes of work-related open globe injuries in the most industrialized region of Turkey. Materials and Methods: The demographic and medical records of patients with work-related open globe injuries who presented to the ophthalmology or emergency departments with an official occupational accident report were retrospectively reviewed. Visual acuity categories were defined according to the World Health Organization. The injury types and zones of the open globes were classified according to Birmingham Eye Trauma Terminology System. Results: Among 479 patients with work-related eye injuries in 5 years, there were 102 eyes of 101 patients with open globe injuries (21%. The mean age of the patients was 34.5±8.9 years with a mean follow-up of 12.5±12.6 months. The injuries peaked in June in the hour between 12:00 and 13:00. Eighty-six percent presented to emergency services within 12 hours after the injury. Twenty-two percent of the patients had been wearing protective eyewear at the time of injury. The open globe injuries were penetrating in 51%, intraocular foreign body in 40%, rupture in 7% and perforation in 2% of the eyes. The most frequent finding was traumatic cataract. Final visual acuity of 33.3% of patients was below 3/60. Seventy-eight percent of patients that had visual acuity worse than 6/18 at presentation had visual acuity of 6/18 or better at final visit. Sixty-three percent of eyes which had injuries involving all 3 zones resulted in phthisis bulbi, enucleation or evisceration. Conclusion: Work-related open globe injuries may have severe consequences such as visual impairment and blindness among the young male working population in industrialized areas. Nearly half of the occupational open globe injuries resulted in visual impairment and blindness.

Yrityksen näkyvyyden lisääminen sosiaalisessa mediassa, Case Globe Hope

OpenAIRE

Asikainen, Miisa

2016-01-01

Opinnäytetyön tarkoituksena oli selvittää, kuinka lisätään näkyvyyttä jo olemassa olevan yrityksen sosiaalisen median kanavien aktivoimisella. Työn toimeksianto tuli suomalaiselta Globe Hope –nimiseltä design-alan yritykseltä. Globe Hope valmistaa tuotteensa kierrätys- sekä ylijäämämateriaaleista. Sosiaalisen median markkinoinnin tutkimus sekä opinnäytetyöntekijän opinnot muotimarkkinoinnin parissa toimivat työn pohjana. Työn tavoite oli selvittää erilaisia keinoja kasvattaa näkyvyyttä sosiaa...

Penile enlargement: from medication to surgery.

Science.gov (United States)

Nugteren, Helena M; Balkema, G T; Pascal, A L; Schultz, W C M Weijmar; Nijman, J M; van Driel, M F

2010-01-01

Penis lengthening pills, stretch apparatus, vacuum pumps, silicone injections, and lengthening and thickening operations are available for men who worry about their penis size. Surgery is thus far the only proven scientific method for penile enlargement. In this article, we consider patient selection, outcome evaluation, and techniques applied. In our view, sexological counseling and detailed explanation of risks and complications are mandatory before any operative intervention.

Mediastinal lymph node enlargement on CT scans in idiopathic pulmonary fibrosis

International Nuclear Information System (INIS)

Ahn, Joong Mo; Im, Jung Gi; Yu, Kyu In; Kim, Hyeong Seog; Kim, Dae Young; Yu, Pil Mun

1992-01-01

The increase in size of lymph node on CT scan is the single most important finding of lymphadenopathy. The purpose of this study was to evaluate the size of mediastinal lymph nodes in patients with idiopathic pulmonary fibrosis with no evidence of malignancy or current infection. CT scans of 70 patients (16 with conventional CT and 54 with high-resolution CT) were assessed for lymph node size and location. The duration of symptoms, and the extent and pattern of the parenchymal lung disease on CT scans were correlated with lymph node enlargement. In 54 of 70 patients, more than one lymph nodes were large than 1-1.5 cm. The prevalence of node enlargement increased significant with a longer duration of symptom (p=0.001), large extent of the disease (p=0.043), and with a greater proportion of honeycomb pattern (p=0.033). Right paratracheal, subcarinal, right tracheobronchial, and paraesophageal nodes were the most common sites of node enlargement. In conclusion, mediastinal lymph node enlargement is common in patients with idiopathic pulmonary fibrosis and is more frequently seen in patients with a longer duration of clinical symptoms, greater extent of the disease, and with a larger proportion of honeycomb pattern

Mediastinal lymph node enlargement on CT scans in idiopathic pulmonary fibrosis

Energy Technology Data Exchange (ETDEWEB)

Ahn, Joong Mo; Im, Jung Gi; Yu, Kyu In; Kim, Hyeong Seog [Seoul National University College of Medicine, Seoul (Korea, Republic of); Kim, Dae Young [Chung Buk National University College of Medicine, Chungju (Korea, Republic of); Yu, Pil Mun [Dankuk University College of Medicine, Seoul (Korea, Republic of)

1992-09-15

The increase in size of lymph node on CT scan is the single most important finding of lymphadenopathy. The purpose of this study was to evaluate the size of mediastinal lymph nodes in patients with idiopathic pulmonary fibrosis with no evidence of malignancy or current infection. CT scans of 70 patients (16 with conventional CT and 54 with high-resolution CT) were assessed for lymph node size and location. The duration of symptoms, and the extent and pattern of the parenchymal lung disease on CT scans were correlated with lymph node enlargement. In 54 of 70 patients, more than one lymph nodes were large than 1-1.5 cm. The prevalence of node enlargement increased significant with a longer duration of symptom (p=0.001), large extent of the disease (p=0.043), and with a greater proportion of honeycomb pattern (p=0.033). Right paratracheal, subcarinal, right tracheobronchial, and paraesophageal nodes were the most common sites of node enlargement. In conclusion, mediastinal lymph node enlargement is common in patients with idiopathic pulmonary fibrosis and is more frequently seen in patients with a longer duration of clinical symptoms, greater extent of the disease, and with a larger proportion of honeycomb pattern.

The dilemmas of tax coordination in the enlarged European Union

DEFF Research Database (Denmark)

Brøchner, Jens; Jensen, Jesper; Svensson, Patrik

2007-01-01

This study evaluates the economic effects of corporate tax coordination in the enlarged European Union (EU) using a computable general equilibrium model. Our main findings are as follows: (i) Corporate tax coordination can yield modest aggregate welfare gains. The 2004 enlargement of the EU has...... elaborate compensation mechanisms. (iii) The large and diverse country effects suggest that Enhanced Cooperation for a subset of the Member States may be the most likely route towards tax coordination. (iv) Identifying winners and losers from coordination for the purpose of a compensation mechanism may...

Spleen and liver enlargement in a patient with rheumatoid arthritis.

Science.gov (United States)

Bedoya, María Eugenia; Ceccato, Federico; Paira, Sergio

2015-01-01

We describe the case of a 51-year-old woman with a seropositive, erosive, and non-nodular rheumatoid arthritis of 15 year of evolution. The patient had poor compliance with medical visits and treatment. She came to the clinic with persistent pancytopenia and spleen and liver enlargement. Liver and bone marrow biopsies were carried out and amyloidosis, neoplasias and infections were ruled out. We discuss the differential diagnosis of pancytopenia and spleen and liver enlargement in a long-standing rheumatoid arthritis patient. Copyright © 2014 Elsevier España, S.L.U. All rights reserved.

Etiologic significance of enlargement of the left atrial appendage in adults

International Nuclear Information System (INIS)

Green, C.E.; Kelley, M.J.; Higgins, C.B.

1982-01-01

Fifty-one patients were divided into two groups: 20 patients with proven rheumatic mitral valve disease (RMVD) and 31 patients with left atrial enlargement (LAE) of a nonrheumatic etiology. The latter group included patients with ischemic papillary muscle dysfunction, mitral valve prolapse, and congestive cardiomyopathy. Radiographic studies showed that enlargement of the left atrial appendage (LAAE) was present in 18 of 20 rheumatics but in only one of 31 nonrheumatics. There was no direct relationship between enlargement of the LAA and radiographic or echocardiographic left atrial size, degree of pulmonary venous hypertension (PVH), or presence of atrial fibrillation. It is postulated that rheumatic influammation of the LAA allows it to dilate out of proportion to the body of the left atrium. In the adult patient with radiographic findings of PVH, LAAE is a valuable and specific radiographic sign of rheumatic mitral valve disease

Isolated amygdala enlargement in temporal lobe epilepsy: A systematic review.

Science.gov (United States)

Beh, S M Jessica; Cook, Mark J; D'Souza, Wendyl J

2016-07-01

The objective of this study was to compare the seizure characteristics and treatment outcomes in patient groups with temporal lobe epilepsy (TLE) identified with isolated amygdala enlargement (AE) on magnetic resonance imaging studies. PubMed, Embase, and the Cochrane Library were searched for relevant studies using the keywords 'amygdala enlargement', 'epilepsy', and 'seizures' in April 2015. Human studies, written in English, that investigated cohorts of patients with TLE and AE were included. Of 204 abstracts initially identified using the search strategy, 14 studies met the inclusion criteria (11 epilepsy studies and 3 psychiatry studies). Ultimately, 8 full studies on AE and TLE involving 107 unique patients were analyzed. Gender distribution consisted of 50 males and 57 females. Right amygdala enlargement was seen in 39 patients, left enlargement in 58 patients, and bilateral enlargement in 7 patients. Surgical resection was performed in 28 patients, with the most common finding being dysplasia/hamartoma or focal cortical dysplasia. Most studies involved small samples of less than 12 patients. There was a wide discrepancy in the methods used to measure amygdala volume, in both patients and controls, hindering comparisons. Most TLE with AE studies observed a later age of seizure onset (mean: 32.2years) compared with studies involving TLE with HS (mean of mid- to late childhood). A higher frequency of complex partial seizures compared with that of convulsive seizures is seen in patients with AE (67-100% vs. 26-47%), and they have an excellent response to antiepileptic drugs (81.8%-100% of seizure-free patients). All studies that included controls also found a significant difference in frequency of seizure types between their cases and controls. Reliable assessment of amygdala volume remains a critical issue hindering better understanding of the clinical management and research of this focal epilepsy syndrome. Within these limitations, the literature suggests

Heavenly Networks. Celestial Maps and Globes in Circulation between Artisans, Mathematicians, and Noblemen in Renaissance Europe.

Science.gov (United States)

Gessner, Samuel

2015-01-01

The aim of this paper is to examine the iconography on a set of star charts by Albrecht Dürer (1515), and celestial globes by Caspar Vopel (1536) and Christoph Schissler (1575). The iconography on these instruments is conditioned by strong traditions which include not only the imagery on globes and planispheres (star charts), but also ancient literature about the constellations. Where this iconography departs from those traditions, the change had to do with humanism in the sixteenth century. This "humanistic" dimension is interwoven with other concerns that involve both "social" and "technical" motivations. The interplay of these three dimensions illustrates how the iconography on celestial charts and globes expresses some features of the shared knowledge and shared culture between artisans, mathematicians, and nobles in Renaissance Europe.

The reliability and validity of the Danish Draft Board Cognitive Ability Test: Børge Prien's Prøve.

Science.gov (United States)

Teasdale, Thomas W; Hartmann, Peter V W; Pedersen, Christoffer H; Bertelsen, Mette

2011-04-01

The Danish Draft Board has used the same test for assessing general cognitive ability, the Børge Prien's Prøve (BPP), for over 50 years during which time all men on reaching the age of 18 become liable for conscription. Data from the test has, over the decades, been used in numerous and wide-ranging research studies. Nonetheless, owing to the special circumstances of its administration, some psychometric properties, which are generally assessed for psychological tests, have not previously been investigated for the BPP. First, since the test is only used at the assessment phase, retesting with the BPP occurs only rarely and under exceptional circumstances. Therefore, its Test-Retest reliability has hitherto not been documented. Second, questions have often been raised as to whether the validity of the BPP is undermined by either a lack of motivation and under-performing among some of the men taking the test, being, as they are, compelled to do so, and/or by gradual obsolescence of the test over the decades of its use. We here present findings from three new studies to show that (a) the BPP has a satisfactory Test-Retest reliability, r=0.77, (b) BPP test scores are not positively associated with expressed attitude to being called upon to serve conscription and (c) the correlation between the BPP and a measure of educational level has remained stable (at about 0.5) through the last two decades. Taken together these three findings further support the continuing value of the BPP in research relating to cognitive ability. © 2010 The Authors. Scandinavian Journal of Psychology © 2010 The Scandinavian Psychological Associations.

Astronomy Meets the Environmental Sciences: Using GLOBE at Night Data

Science.gov (United States)

Barringer, D.; Walker, C. E.; Pompea, S. M.; Sparks, R. T.

2011-09-01

The GLOBE at Night database now contains over 52,000 observations from the five annual two-week campaigns. It can be used as a resource to explore various issues related to light pollution and our environment. Students can compare data over time to look for changes and trends. For example, they can compare the data to population density or with nighttime photography and spectroscopy of lights. The data can be used in a lighting survey, to search for dark sky oases or to monitor ordinance compliance. Students can study effects of light pollution on animals, plants, human health, safety, security, energy consumption, and cost. As an example, we used data from the GLOBE at Night project and telemetry tracking data of lesser long-nosed bats obtained by the Arizona Game and Fish Department to study the effects of light pollution on the flight paths of the bats between their day roosts and night foraging areas around the city of Tucson, AZ. With the visual limiting magnitude data from GLOBE at Night, we ran a compositional analysis with respect to the bats' flight paths to determine whether the bats were selecting for or against flight through regions of particular night sky brightness levels. We found that the bats selected for the regions in which the limiting sky magnitudes fell between the ranges of 2.8-3.0 to 3.6-3.8 and 4.4-4.6 to 5.0-5.2, suggesting that the lesser long-nosed bat can tolerate a fair degree of urbanization. We also compared this result to contour maps created with digital Sky Quality Meter (http://www.unihedron.com) data.

Long term follow up of idiopathic gingival enlargement associated with chronic periodontitis: A case report and review

OpenAIRE

Girish P Nagarale; S Ravindra; Srinath Thakur; Swati Setty

2013-01-01

Background: Idiopathic gingival enlargement is a rare condition characterized by massive enlargement of the gingiva. It may be associated with other diseases/conditions characterizing a syndrome, but rarely associated with periodontitis. Case Description: This case report describes an unusual clinical form of gingival enlargement associated with chronic periodontitis. Clinical examination revealed diffuse gingival enlargement. The lesion was asymptomatic, firm, and pinkish red. Generalized pe...

Globe at Night: From IYA2009 to the International Year of Light 2015 and Beyond

Science.gov (United States)

Walker, Constance Elaine; Pompea, Stephen M.; Sparks, Robert T.

2015-08-01

Citizen-science is a rewardingly inclusive way to bring awareness to the public on important issues like the disappearing starry night sky, its cause and solutions. Citizen-science can also provide meaningful, hands-on “science process” experiences for students. One program that does both is Globe at Night (www.globeatnight.org), an international campaign to raise public awareness of the impact of light pollution by having people measure night-sky brightness and submit observations via a “web app” on any smart device or computer. Additionally, 2 native mobile apps - Loss of the Night for iPhone & Android, and Dark Sky Meter for iPhone - support Globe at Night.Since 2006, more than 125,000 vetted measurements from 115 countries have been reported. For 2015 the campaign is offered as a 10-day observation window each month when the Moon is not up. To facilitate Globe at Night as an international project, the web app and other materials are in many languages. (See www.globeatnight.org/downloads.)Students and the general public can use the data to monitor levels of light pollution around the world, as well as understand light pollution’s effects on energy consumption, plants, wildlife, human health and our ability to enjoy a starry night sky. Projects have compared Globe at Night data with ground-truthing using meters for energy audits as well as with data on birds and bats, population density, satellite data and trends over time. Globe at Night tackles grand challenges and everyday problems. It provides resources for formal and informal educators to engage learners of all ages. It has 9 years of experience in best practices for data management, design, collection, visualization, interpretation, etc. It has externally evaluated its program, workshops, lesson plans and accompanying kit to explore reasons for participation, skills developed, impact of experiences and perceived outcomes. Three recent papers (Birriel et al. 2014; Kyba et al. 2013; 2015) verify the

Bacterial Cell Enlargement Requires Control of Cell Wall Stiffness Mediated by Peptidoglycan Hydrolases.

Science.gov (United States)

Wheeler, Richard; Turner, Robert D; Bailey, Richard G; Salamaga, Bartłomiej; Mesnage, Stéphane; Mohamad, Sharifah A S; Hayhurst, Emma J; Horsburgh, Malcolm; Hobbs, Jamie K; Foster, Simon J

2015-07-28

Most bacterial cells are enclosed in a single macromolecule of the cell wall polymer, peptidoglycan, which is required for shape determination and maintenance of viability, while peptidoglycan biosynthesis is an important antibiotic target. It is hypothesized that cellular enlargement requires regional expansion of the cell wall through coordinated insertion and hydrolysis of peptidoglycan. Here, a group of (apparent glucosaminidase) peptidoglycan hydrolases are identified that are together required for cell enlargement and correct cellular morphology of Staphylococcus aureus, demonstrating the overall importance of this enzyme activity. These are Atl, SagA, ScaH, and SagB. The major advance here is the explanation of the observed morphological defects in terms of the mechanical and biochemical properties of peptidoglycan. It was shown that cells lacking groups of these hydrolases have increased surface stiffness and, in the absence of SagB, substantially increased glycan chain length. This indicates that, beyond their established roles (for example in cell separation), some hydrolases enable cellular enlargement by making peptidoglycan easier to stretch, providing the first direct evidence demonstrating that cellular enlargement occurs via modulation of the mechanical properties of peptidoglycan. Understanding bacterial growth and division is a fundamental problem, and knowledge in this area underlies the treatment of many infectious diseases. Almost all bacteria are surrounded by a macromolecule of peptidoglycan that encloses the cell and maintains shape, and bacterial cells must increase the size of this molecule in order to enlarge themselves. This requires not only the insertion of new peptidoglycan monomers, a process targeted by antibiotics, including penicillin, but also breakage of existing bonds, a potentially hazardous activity for the cell. Using Staphylococcus aureus, we have identified a set of enzymes that are critical for cellular enlargement. We

Cross-border transfer of knowledge: Cultural lessons from project GLOBE

NARCIS (Netherlands)

Javidan, Mansour; Stahl, Günther K.; Brodbeck, Felix; Wilderom, Celeste P.M.

2005-01-01

Distant cross-border business is on the rise. It necessitates effective transfer of knowledge across geographic and cultural borders. In this article we present the key results from the GLOBE study of 62 cultures and apply them to a real-life case of a North European business school designing and

MSIs across the Globe: Laying the Foundation for Future Research

Science.gov (United States)

Hallmark, Tyler; Gasman, Marybeth

2018-01-01

In this paper, we explore the role that Minority Serving Institutions (MSIs) play in democratizing education in the USA and around the world, examining both the institutions and their larger context. We also put forth recommendations for reaching and empowering students attending MSIs and "students at the margins" across the globe.

Ethics and Corporal Punishment within the Schools across the Globe

Science.gov (United States)

Rajdev, Usha

2012-01-01

This paper contains cultural anthropological research on various discipline measures used within the classrooms in India, United Kingdom, China, Africa, and the United States. My recent visit to schools in India on study abroad programs prompted my desire to research across the globe different methods of classroom management discipline conducted…

Science and Math in the Library Media Center Using GLOBE.

Science.gov (United States)

Aquino, Teresa L.; Levine, Elissa R.

2003-01-01

Describes the Global Learning and Observations to Benefit the Environment (GLOBE) program which helps school library media specialists and science and math teachers bring earth science, math, information literacy, information technology, and student inquiry into the classroom. Discusses use of the Internet to create a global network to study the…

Asymmetric Meckel Cave Enlargement: A Potential Marker of PHACES Syndrome.

Science.gov (United States)

Wright, J N; Wycoco, V

2017-06-01

PHACES syndrome is a complex of morphologic abnormalities of unknown cause and includes posterior fossa abnormalities; head and neck infantile hemangiomas; arterial, cardiac, and eye anomalies; and sternal or abdominal wall defects. Accurate identification of the syndrome is important for optimal treatment. The purpose of this study was to investigate the incidence of asymmetric Meckel cave enlargement, a potential novel imaging marker, in a population of patients referred for evaluation of possible PHACES syndrome. Eighty-five patients referred for neuroimaging evaluation of possible PHACES syndrome were identified and stratified on the basis of their ultimate clinical PHACES diagnosis categorization into PHACES, possible PHACES, or not PHACES. MR imaging studies were subsequently reviewed for the presence or absence of unilateral Meckel cave enlargement, with the reviewer blinded to the ultimate PHACES syndrome categorization. Twenty-five of 85 patients (29%) were ultimately categorized as having PHACES or possible PHACES according to consensus guidelines. Asymmetric Meckel cave enlargement was present in 76% (19/25) of these patients and in 82% (19/23) of only those patients with definite PHACES. This finding was present in none of the 60 patients determined not to have PHACES syndrome. In 7/19 patients (37%) with this finding, subtle MR imaging abnormalities consistent with PHACES were missed on the initial MR imaging interpretation. Asymmetric Meckel cave enlargement was a common feature of patients with PHACES in our cohort and may serve as a novel imaging marker. Increased awareness of this imaging feature has the potential to increase the diagnostic accuracy of PHACES. © 2017 by American Journal of Neuroradiology.

The Use of the Nelder-Mead Method in Determining Projection Parameters for Globe Photographs

Science.gov (United States)

Gede, M.

2009-04-01

A photo of a terrestrial or celestial globe can be handled as a map. The only hard issue is its projection: the so-called Tilted Perspective Projection which, if the optical axis of the photo intersects the globe's centre, is simplified to the Vertical Near-Side Perspective Projection. When georeferencing such a photo, the exact parameters of the projections are also needed. These parameters depend on the position of the viewpoint of the camera. Several hundreds of globe photos had to be georeferenced during the Virtual Globes Museum project, which made necessary to automatize the calculation of the projection parameters. The author developed a program for this task which uses the Nelder-Mead Method in order to find the optimum parameters when a set of control points are given as input. The Nelder-Mead method is a numerical algorithm for minimizing a function in a many-dimensional space. The function in the present application is the average error of the control points calculated from the actual values of parameters. The parameters are the geographical coordinates of the projection centre, the image coordinates of the same point, the rotation of the projection, the height of the perspective point and the scale of the photo (calculated in pixels/km). The program reads the Global Mappers Ground Control Point (.GCP) file format as input and creates projection description files (.PRJ) for the same software. The initial values of the geographical coordinates of the projection centre are calculated as the average of the control points, while the other parameters are set to experimental values which represent the most common circumstances of taking a globe photograph. The algorithm runs until the change of the parameters sinks below a pre-defined limit. The minimum search can be refined by using the previous result parameter set as new initial values. This paper introduces the calculation mechanism and examples of the usage. Other possible other usages of the method are

Evaluation of Occupational Closed Globe Eye Injuries

Directory of Open Access Journals (Sweden)

Berna Akova-Budak

2016-01-01

Full Text Available Aim: To evaluate closed glob injuries related to occupational accidents of patients who had official occupational accident records. Material and Method: The medical records of patients with ocular injuries who referred to Department of Ophthalmology or emergency of Uludag University, School of Medicine between January 2010 and December 2013 with official occupational accident report were retrospectively reviewed. The patients with closed globe injuries following trauma were included. Age, sex, the injured eye, the cause of the trauma, whether the precautions were taken or not by the patient, the damage due to trauma were recorded. Results: According to the official records, 108 patients referred to our clinic with closed globe injury related to occupational accident. One hundred twenty eyes of 108 patients ( 2 females, 106 males were evaluated. The mean age of the patients was 33±8.6 years. The most frequent cause of injury was foreign bodies on the ocular surface followed by blunt trauma. The mean age of the patients injured with foreign bodies was found to be significantly lower than the patients injured with blunt objects (p=0.039. Thirteen patients reported that they had used preventive equipment. Discussion: It is of utmost importance that the awareness of the workers should be raised and they should be educated about the use of preventive equipment to prevent the occupational eye injuries. The education of particularly the younger patients about the occupational injuries when they begin to work may decrease the rate of occupational accident related eye injuries.

The paradox of EU enlargement and member states' policies: Dilemmas and challenges: The case of Portugal

Directory of Open Access Journals (Sweden)

Neves Santos Miguel

2016-01-01

Full Text Available The paper addresses the issue of EU enlargement with its dual nature: of an intra-EU process, related to the consolidation of a democratic-peace based on collective security, and an external process, involving EU foreign policy and impact on relations with other major global players. Although enlargement is a multidimensional process that combines different perspectives - candidate countries' enlargement politics, member states' politics/policy, EU enlargement politics and external global impact - the paper focuses on Member States policies towards enlargement by looking at the case of Portugal, in particular in relation with the Big Bang Eastern enlargement, and aims at explaining the paradox of Portugal's strong political support to enlargement while it was one of the main potential losers in terms of economic interests. A 'foreign policy analysis' framework is adopted in order to understand the process of decision-making and the interaction between the domestic and the EU levels. The argument put forward is that an exclusive constructivist approach does not provide a satisfactory explanation, as there was also rationalist-interest logic at play. The Portuguese policy towards enlargement was determined not only by the 'solidaritysimilarity' logic, dominant in the formal political discourse but also by the consideration of long-term interests in the EU related to the preservation of the strategic alliance with Germany. The overall systemic impact of enlargement tends to weaken the EU as it presents a major paradox functioning as a double-edged sword. While it has a positive impact by contributing to the enhancement of the EU international profile as it grows in size raising expectations about its potential global role, it also leads to greater heterogeneity, undermining the EU cohesion and its ability to act together with a single voice becoming a robust global player, thus frustrating the expectations raised in the first place.

Investigating the role of urban development in the conventional environmental Kuznets curve: evidence from the globe.

Science.gov (United States)

Katircioglu, Setareh; Katircioglu, Salih; Kilinc, Ceyhun C

2018-03-19

We investigated the role of urbanization in the conventional environmental Kuznets curve (EKC) of the globe. The overall population and rural population were also considered for control purposes. Based on our findings, we suggest that the conventional EKC of the globe is not an inverted U-shape but becomes downward sloping when urban development is added and inverted U-shapes when the overall population and rural population volumes are added.

Tablet and Face-to-Face Hybrid Professional Development: Providing Earth Systems Science Educators Authentic Research Opportunities through The GLOBE Program at Purdue University

Science.gov (United States)

Wegner, K.; Branch, B. D.; Smith, S. C.

2013-12-01

The Global Learning and Observations to Benefit the Environment (GLOBE) program is a worldwide hands-on, primary and secondary school-based science and education program (www.globe.gov). GLOBE's vision promotes and supports students, teachers and scientists to collaborate on inquiry-based authentic science investigations of the environment and the Earth system working in close partnership with NASA, NOAA and NSF Earth System Science Projects (ESSP's) in study and research about the dynamics of Earth's environment. GLOBE Partners conduct face-to-face Professional Development in more than 110 countries, providing authentic scientific research experience in five investigation areas: atmosphere, earth as a system, hydrology, land cover, and soil. This presentation will provide a sample for a new framework of Professional Development that was implemented in July 2013 at Purdue University lead by Mr. Steven Smith who has tested GLOBE training materials for future training. The presentation will demonstrate how institutions can provide educators authentic scientific research opportunities through various components, including: - Carrying out authentic research investigations - Learning how to enter their authentic research data into the GLOBE database and visualize it on the GLOBE website - Learn how to access to NASA's Earth System Science resources via GLOBE's new online 'e-Training Program' - Exploring the connections of their soil protocol measurements and the history of the soil in their area through iPad soils app - LIDAR data exposure, Hydrology data exposure

A morphologically preserved multi-resolution TIN surface modeling and visualization method for virtual globes

Science.gov (United States)

Zheng, Xianwei; Xiong, Hanjiang; Gong, Jianya; Yue, Linwei

2017-07-01

Virtual globes play an important role in representing three-dimensional models of the Earth. To extend the functioning of a virtual globe beyond that of a "geobrowser", the accuracy of the geospatial data in the processing and representation should be of special concern for the scientific analysis and evaluation. In this study, we propose a method for the processing of large-scale terrain data for virtual globe visualization and analysis. The proposed method aims to construct a morphologically preserved multi-resolution triangulated irregular network (TIN) pyramid for virtual globes to accurately represent the landscape surface and simultaneously satisfy the demands of applications at different scales. By introducing cartographic principles, the TIN model in each layer is controlled with a data quality standard to formulize its level of detail generation. A point-additive algorithm is used to iteratively construct the multi-resolution TIN pyramid. The extracted landscape features are also incorporated to constrain the TIN structure, thus preserving the basic morphological shapes of the terrain surface at different levels. During the iterative construction process, the TIN in each layer is seamlessly partitioned based on a virtual node structure, and tiled with a global quadtree structure. Finally, an adaptive tessellation approach is adopted to eliminate terrain cracks in the real-time out-of-core spherical terrain rendering. The experiments undertaken in this study confirmed that the proposed method performs well in multi-resolution terrain representation, and produces high-quality underlying data that satisfy the demands of scientific analysis and evaluation.

Epidemiologic characteristics and outcomes of open globe injury in Shanghai

Directory of Open Access Journals (Sweden)

Yong-Rong Ji

2017-08-01

Full Text Available AIM: To investigate the epidemiologic characteristics and outcomes of open globe injury in Shanghai. METHODS: A retrospective study was conducted for 148 unilateral open globe injury cases presenting to a tertiary referral hospital of Shanghai. Electronic medical records were reviewed and phone surveys were conducted to collect and analyze 1 background of patient; 2 setting of injury and clinical signs at presentation; 3 treatment procedure and outcome; 4 quality of life after injury. RESULTS: There were more male patients (77.03% than females (22.97%, more temporary habitants (79.05% than residents (20.95%. The subjects in this study presented a significantly lower constitutional status of education than that of the whole Shanghai population (P<0.001. Occupational injury was the first cause of injuries (39.86%, followed by home accident (20.27%, road accident (16.89%, violent behavior (16.89% and outdoor injury (6.08%. The 143 subjects (96.62% were not wearing spectacles at the time of injury. Of all patients, 77 subjects (52.03% had the outcome of no vision (including enucleation. The classification and regression tree (CART prognosis presents 59.58% sensitivity to predict visual survival correctly and 80.19% specificity to predict no vision correctly. The patients whose injured eye had no vision reported more reduction of life quality. CONCLUSION: We found that male subject, temporary habitants, low educational status and no eyewear are risk factors of open globe injury in Shanghai. Occupational injury is the leading cause. CART analysis presents a certain agreement to the actual visual outcome. The injury imposes negative impact on quality of life especially in no vision cases. The education of eye protection may help to avoid the injury.

ATRF Earns Three Green Globes, Exceeds NIH Building Standards | Poster

Science.gov (United States)

By Ashley DeVine, Staff Writer From project management and energy and water efficiency to emissions and the indoor environment, the Advanced Technology Research Facility (ATRF) was built with sustainability in mind, exceeding the National Institutes of Health’s (NIH’s) building standards and earning three Green Globes from the Green Building Initiative (GBI).

Open globe injury with an interesting intra-ocular foreign body

Directory of Open Access Journals (Sweden)

Gill, Ekjyot

2017-07-01

Full Text Available Introduction: Cases of penetrating ocular trauma due to osseous material are limited, so reported incidents are valuable in determining outcomes and proper treatment courses.Case description: We report a case of an open globe injury of the left eye with an intraocular foreign body occurring after a firework exploded in the hand of a 22-year-old man. The patient presented with light perception vision in the injured eye with a full-thickness limbal laceration and dense hyphema obscuring fundoscopy. CT scan revealed a hyperdense foreign body juxtaposed to the lens. Immediate surgical intervention to repair the globe rupture revealed a defect in the anterior capsule and small, white objects in the posterior chamber that were promptly removed. Pathologic investigation determined these fragments to be cortical bone likely from the patient’s phalanges. Results and discussion: There was no evidence of endophthalmitis or keratitis from time of injury to the five-month follow-up, suggesting that the risk of infection may be low and therefore it may be reasonable to manage these injuries with a period of observation.

Amygdala and hippocampus enlargement during adolescence in autism.

NARCIS (Netherlands)

Groen, W.B.; Teluij, M.; Buitelaar, J.K.; Tendolkar, I.

2010-01-01

OBJECTIVE: The amygdala and hippocampus are key components of the neural system mediating emotion perception and regulation and are thought to be involved in the pathophysiology of autism. Although some studies in children with autism suggest that there is an enlargement of amygdala and hippocampal

Childhood asymmetrical labium majus enlargement sonographic and MR imaging appearances

Energy Technology Data Exchange (ETDEWEB)

Gokli, Ami; Neuman, Jeremy; Lukse, Ruby; Koshy, June [Staten Island University Hospital, Department of Radiology, Staten Island, NY (United States); Kong, Fanyi [Staten Island University Hospital, Department of Pathology, Staten Island, NY (United States); Laor, Tal [Cincinnati Children' s Hospital Medical Center, Department of Radiology, Cincinnati, OH (United States)

2016-05-15

Childhood asymmetrical labium majus enlargement (CALME) has been described sparsely in recent surgery, pathology, pediatric and gynecology literature; however, no comprehensive description from a radiology perspective has been developed. The purpose of this case series is to describe the imaging findings of CALME and to review the current understanding of this recently described clinical entity with regard to clinical presentation, pathophysiology, differential diagnosis and treatment options. This is a retrospective analysis of 3 girls, ages 5-7 years, who presented for imaging evaluation with subsequent pathologically proven CALME. Each child's clinical history, length of symptoms, imaging appearance and pathological findings were reviewed. All three girls presented with unilateral enlargement of the labium majus (two right-side, one left-side) with no history of trauma or other inciting cause. Two girls had painless labial enlargement that was recognized for weeks, and one had similar symptoms for 1 year prior to presentation. One girl was evaluated initially with sonography, and all three children underwent MR imaging. Sonographic evaluation showed asymmetrical labial enlargement without a definable mass. In each girl, the MR imaging findings were characterized by relatively ill-defined T1-weighted hypointense signal, T2-weighted hypo- to isointense signal with interspersed hyperintense septae, and heterogeneous patchy and feathery strands of enhancement on post-contrast imaging. Biopsy from each child showed benign fibrous tissue with intervening mature fibroadipose tissue, vessels and nerves without findings of inflammation or neoplasia. The MR imaging appearance of CALME is consistent. Recognition and appreciation of this unique pediatric entity by the radiologist may be essential for appropriate diagnosis and can help to guide therapy. Current preferred treatment approach is conservative. (orig.)

Childhood asymmetrical labium majus enlargement sonographic and MR imaging appearances

International Nuclear Information System (INIS)

Gokli, Ami; Neuman, Jeremy; Lukse, Ruby; Koshy, June; Kong, Fanyi; Laor, Tal

2016-01-01

Childhood asymmetrical labium majus enlargement (CALME) has been described sparsely in recent surgery, pathology, pediatric and gynecology literature; however, no comprehensive description from a radiology perspective has been developed. The purpose of this case series is to describe the imaging findings of CALME and to review the current understanding of this recently described clinical entity with regard to clinical presentation, pathophysiology, differential diagnosis and treatment options. This is a retrospective analysis of 3 girls, ages 5-7 years, who presented for imaging evaluation with subsequent pathologically proven CALME. Each child's clinical history, length of symptoms, imaging appearance and pathological findings were reviewed. All three girls presented with unilateral enlargement of the labium majus (two right-side, one left-side) with no history of trauma or other inciting cause. Two girls had painless labial enlargement that was recognized for weeks, and one had similar symptoms for 1 year prior to presentation. One girl was evaluated initially with sonography, and all three children underwent MR imaging. Sonographic evaluation showed asymmetrical labial enlargement without a definable mass. In each girl, the MR imaging findings were characterized by relatively ill-defined T1-weighted hypointense signal, T2-weighted hypo- to isointense signal with interspersed hyperintense septae, and heterogeneous patchy and feathery strands of enhancement on post-contrast imaging. Biopsy from each child showed benign fibrous tissue with intervening mature fibroadipose tissue, vessels and nerves without findings of inflammation or neoplasia. The MR imaging appearance of CALME is consistent. Recognition and appreciation of this unique pediatric entity by the radiologist may be essential for appropriate diagnosis and can help to guide therapy. Current preferred treatment approach is conservative. (orig.)

Immunomodulatory Activity of Red Ginseng against Influenza A Virus Infection

Directory of Open Access Journals (Sweden)

Jong Seok Lee

2014-01-01

Full Text Available Ginseng herbal medicine has been known to have beneficial effects on improving human health. We investigated whether red ginseng extract (RGE has preventive effects on influenza A virus infection in vivo and in vitro. RGE was found to improve survival of human lung epithelial cells upon influenza virus infection. Also, RGE treatment reduced the expression of pro-inflammatory genes (IL-6, IL-8 probably in part through interference with the formation of reactive oxygen species by influenza A virus infection. Long-term oral administration of mice with RGE showed multiple immunomodulatory effects such as stimulating antiviral cytokine IFN-γ production after influenza A virus infection. In addition, RGE administration in mice inhibited the infiltration of inflammatory cells into the bronchial lumens. Therefore, RGE might have the potential beneficial effects on preventing influenza A virus infections via its multiple immunomodulatory functions.

Effect analysis of intradermal hyaluronic acid injection to treat enlarged facial pores.

Science.gov (United States)

Qian, Wei; Zhang, Yan-Kun; Hou, Ying; Lyu, Wei; Cao, Qian; Li, Yan-Qi; Fan, Ju-Feng

2017-08-08

To investigate the clinical application and efficacy of intradermal injection of low molecular weight hyaluronic acid (LMW-HA) for treating enlarged facial pores. From January 2015 to May 2016, 42 subjects who sought aesthetic treatment underwent intradermal injection of LMW-HA to improve enlarged facial pores. For each treatment, 2.5 mL (25 mg) of LMW-HA was injected into the skin of the full face. The treatment was repeated 2-5 times with an interval of 1 to 1.5 months between consecutive treatments. The postoperative follow-up period was 1 to 6 months. Statistical analysis was used to compare the degree of enlargement of facial pores before and after injection. The clinical efficacy and adverse effects were recorded. The enlarged facial pores before and after treatment were categorized and subjected to the Wilcoxon matched-pairs signed-rank test. The difference was statistically significant (Pinjection sites in the subjects who sought aesthetic treatment. The overall satisfaction rate was 92.8%. Intradermal injection of LMW-HA can significantly improve skin texture, reduce pore size, and enhance skin radiance. The injection technique was simple, safe, and effective and could easily be extended to clinical practice. © 2017 Wiley Periodicals, Inc.

The Pale Blue Dot: Utilizing Real World Globes in High School and Undergraduate Oceanography Classrooms

Science.gov (United States)

Rogers, D. B.

2017-12-01

Geoscience classrooms have benefitted greatly from the use of interactive, dry-erasable globes to supplement instruction on topics that require three-dimensional visualization, such as seismic wave propagation and the large-scale movements of tectonic plates. Indeed, research by Bamford (2013) demonstrates that using three-dimensional visualization to illustrate complex processes enhances student comprehension. While some geoscience courses tend to bake-in lessons on visualization, other disciplines of earth science that require three-dimensional visualization, such as oceanography, tend to rely on students' prior spatial abilities. In addition to spatial intelligence, education on the three-dimensional structure of the ocean requires knowledge of the external processes govern the behavior of the ocean, as well as the vertical and lateral distribution of water properties around the globe. Presented here are two oceanographic activities that utilize RealWorldGlobes' dry-erase globes to supplement traditional oceanography lessons on thermohaline and surface ocean circulation. While simultaneously promoting basic plotting techniques, mathematical calculations, and unit conversions, these activities touch on the processes that govern global ocean circulation, the principles of radiocarbon dating, and the various patterns exhibited by surface ocean currents. These activities challenge students to recognize inherent patterns within their data and synthesize explanations for their occurrence. Spatial visualization and critical thinking are integral to any geoscience education, and the combination of these abilities with engaging hands-on activities has the potential to greatly enhance oceanography education in both secondary and postsecondary settings

Chronic inflammatory gingival enlargement associated with orthodontic therapy--a case report.

Science.gov (United States)

Jadhav, Tanya; Bhat, K Mahalinga; Bhat, G Subraya; Varghese, Jothi M

2013-02-01

Gingival enlargement, also synonymous with the terms gingival hyperplasia or hypertrophy, is defined as an abnormal overgrowth of gingival tissues. A case of a 19-year-old male presenting with maxillary and mandibular chronic inflammatory gingival enlargement associated with prolonged orthodontic therapy is reported here. Surgical therapy was carried out to provide a good aesthetic outcome. No recurrence was reported at the end of 1 year. The importance of patient motivation and compliance during and after therapy as a critical factor in the success of treatment has also been highlighted through this case report.

Using Calibrated RGB Imagery from Low-Cost Uavs for Grassland Monitoring: Case Study at the Rengen Grassland Experiment (rge), Germany

Science.gov (United States)

Lussem, U.; Hollberg, J.; Menne, J.; Schellberg, J.; Bareth, G.

2017-08-01

Monitoring the spectral response of intensively managed grassland throughout the growing season allows optimizing fertilizer inputs by monitoring plant growth. For example, site-specific fertilizer application as part of precision agriculture (PA) management requires information within short time. But, this requires field-based measurements with hyper- or multispectral sensors, which may not be feasible on a day to day farming practice. Exploiting the information of RGB images from consumer grade cameras mounted on unmanned aerial vehicles (UAV) can offer cost-efficient as well as near-real time analysis of grasslands with high temporal and spatial resolution. The potential of RGB imagery-based vegetation indices (VI) from consumer grade cameras mounted on UAVs has been explored recently in several. However, for multitemporal analyses it is desirable to calibrate the digital numbers (DN) of RGB-images to physical units. In this study, we explored the comparability of the RGBVI from a consumer grade camera mounted on a low-cost UAV to well established vegetation indices from hyperspectral field measurements for applications in grassland. The study was conducted in 2014 on the Rengen Grassland Experiment (RGE) in Germany. Image DN values were calibrated into reflectance by using the Empirical Line Method (Smith & Milton 1999). Depending on sampling date and VI the correlation between the UAV-based RGBVI and VIs such as the NDVI resulted in varying R2 values from no correlation to up to 0.9. These results indicate, that calibrated RGB-based VIs have the potential to support or substitute hyperspectral field measurements to facilitate management decisions on grasslands.

USING CALIBRATED RGB IMAGERY FROM LOW-COST UAVS FOR GRASSLAND MONITORING: CASE STUDY AT THE RENGEN GRASSLAND EXPERIMENT (RGE, GERMANY

Directory of Open Access Journals (Sweden)

U. Lussem

2017-08-01

Full Text Available Monitoring the spectral response of intensively managed grassland throughout the growing season allows optimizing fertilizer inputs by monitoring plant growth. For example, site-specific fertilizer application as part of precision agriculture (PA management requires information within short time. But, this requires field-based measurements with hyper- or multispectral sensors, which may not be feasible on a day to day farming practice. Exploiting the information of RGB images from consumer grade cameras mounted on unmanned aerial vehicles (UAV can offer cost-efficient as well as near-real time analysis of grasslands with high temporal and spatial resolution. The potential of RGB imagery-based vegetation indices (VI from consumer grade cameras mounted on UAVs has been explored recently in several. However, for multitemporal analyses it is desirable to calibrate the digital numbers (DN of RGB-images to physical units. In this study, we explored the comparability of the RGBVI from a consumer grade camera mounted on a low-cost UAV to well established vegetation indices from hyperspectral field measurements for applications in grassland. The study was conducted in 2014 on the Rengen Grassland Experiment (RGE in Germany. Image DN values were calibrated into reflectance by using the Empirical Line Method (Smith & Milton 1999. Depending on sampling date and VI the correlation between the UAV-based RGBVI and VIs such as the NDVI resulted in varying R2 values from no correlation to up to 0.9. These results indicate, that calibrated RGB-based VIs have the potential to support or substitute hyperspectral field measurements to facilitate management decisions on grasslands.

Sustainable development and CERN’s role: Panel discussion at the Globe

CERN Multimedia

CERN Bulletin

2012-01-01

On Thursday 21 June, on the occasion of the UN Rio+20 Conference on Sustainable Development, some ambitious ecological projects involving CERN and its technologies will be presented in an afternoon of lectures and discussions in the Globe. The event is an opportunity for people at CERN to discuss the Organization’s green credentials and their ecological impact on life in the local area.   “The Globe was seen as a metaphor for the planet and a symbol of sustainable development when it was known as the ‘Palace of Equilibrium’ at Expo02 in Switzerland. Now here at CERN, it is the perfect place to host a debate on the role of technology and innovation in this area," enthuses Bernard Pellequer, who is in charge of event planning for the venue. On the afternoon of 21 June, speakers will present several ambitious projects, such as the eco-neighbourhood “Les Vergers”, the Vernes lake in ...

North Atlantic Treaty Organization: Implications Related to Eastward Enlargement

National Research Council Canada - National Science Library

Vaagland, John

1997-01-01

... Truman's Marshall Plan. The study concludes that the main issue as far as Western security is concerned is not a hasty enlargement of NATO but rather how to guarantee peaceful relations between Russia and NATO...

PREDICTING PROGNOSTIC VALUE OF OCULAR TRAUMA SCORE (OTS IN AN OPEN GLOBE INJURY IN TERTIARY EYE CARE HOSPITAL

Directory of Open Access Journals (Sweden)

Rahul

2015-10-01

Full Text Available AIM : To evaluate the prognostic value of OTS in open globe injuries. MATERIAL METHOD : Retrospective analysis of 77 eyes with open globe injuries was done from 01/07/2013 to 31/12/2014. Patients were assigned raw score sum based on initial V/A, and ocular findings then classified into 5 categories for predicting final visual outcome based on ocular Trauma score (OTS. RESULT : We estimated final V/A in 77 cases of open globe injuries (64.93% had raw sc ore between 65.91 (category 3, 4 Six months after the injury, 42.85% patients of categories 1 (raw score 0 - 44 achieved V/A of PL/HM as compared to 17% in OTS study. 16 patients with raw compared to OTS study. We reported comparable visual outcome with OT S study except in category 1 & 2. CONCLUSION: OTS score is valuable in triage, patient counseling and decision making for the management of ocular trauma. We recommend that OTS should be used routinely for open globe injuries as it is a simple guide

The enlargement of geniculate fossa of facial nerve canal: a new CT finding of facial nerve canal fracture

International Nuclear Information System (INIS)

Gong Ruozhen; Li Yuhua; Gong Wuxian; Wu Lebin

2006-01-01

Objective: To discuss the value of enlargement of geniculate fossa of facial nerve canal in the diagnosis of facial nerve canal fracture. Methods: Thirty patients with facial nerve canal fracture underwent axial and coronal CT scan. The correlation between the fracture and the enlargement of geniculate fossa of facial nerve canal was analyzed. The ability of showing the fracture and enlargement of geniculate fossa of facial nerve canal in axial and coronal imaging were compared. Results: Fracture of geniculate fossa of facial nerve canal was found in the operation in 30 patients, while the fracture was detected in CT in 18 patients. Enlargement of geniculate ganglion of facial nerve was detected in 30 patients in the operation, while the enlargement of fossa was found in CT in 28 cases. Enlargement and fracture of geniculate fossa of facial nerve canal were both detected in CT images in 18 patients. Only the enlargement of geniculate fossa of facial nerve canal was shown in 12 patients in CT. Conclusion: Enlargement of geniculate fossa of facial nerve canal was a useful finding in the diagnosis of fracture of geniculate fossa in patients with facial paralysis, even no fracture line was shown on CT images. (authors)

Trial-by-fire transformation: an interview with Globe Metallurgical's Arden C. Sims. Interview by Bruce Rayner.

Science.gov (United States)

Sims, A C

1992-01-01

Globe Metallurgical Inc., a $115 million supplier of specialty metals, is best known as the first small company to win the Baldrige Award in 1988. But there is much more to this gutsy little company than total quality. During the 1980s, Globe transformed itself from a rust-belt has-been on the verge of bankruptcy into a high-technology, high-quality industry leader. Along the way, the company went private in a management-led leveraged buyout, embraced flexible work teams, adopted a high-value-added, niche marketing strategy, and took its business global. Leading the way in Globe's reinvention was Chief Executive Arden C. Sims, the slow-talking son of a West Virginian coal miner. When he joined the company in 1984, Sims had no experience in the new managerial techniques. He was a product of the old school of management: cut costs and trim operations to regain competitiveness. But he soon discovered that old-style management was not enough to battle offshore competitors, an unproductive work force, rising costs, and outdated production technology. He was forced to go looking for new ideas and practices. In a succession of learning experiences, Sims attended a seminar on total quality in 1985, paving the way for the company's quality program; he discovered the power of flexible work teams when management was forced to run the furnaces during a year-long strike; he organized an LBO, allowing him to change the work order even more dramatically; and he took the company global and into highly profitable niche markets by severing a long-standing relationship with Globe's sales and marketing representative. As a result of these and other changes, Globe leads the specialty metals industry in virtually all performance measures.

Prolactin deficiency, obesity, and enlarged testes--a new syndrome?

Science.gov (United States)

Roitman, A; Assa, S; Kauli, R; Laron, Z

1980-01-01

A 4-year-old boy is described who was obese and slightly mentally retarded. His testes were enlarged. The only endocrine disorder present was a failure to increase plasma prolactin after stimulation. Images Figure PMID:7436524

Pain following foraminal enlargement in mandibular molars with necrosis and apical periodontitis: A randomized controlled trial.

Science.gov (United States)

Saini, H R; Sangwan, P; Sangwan, A

2016-12-01

This randomized controlled trial was conducted to evaluate the effect of foraminal enlargement during chemomechanical root canal preparation on postoperative pain. Seventy mandibular first molars with asymptomatic pulp necrosis and chronic apical periodontitis were randomized into two groups - foraminal enlargement (FE) and conventional nonforaminal enlargement (NFE). Canals were prepared according to the respective protocols, and the teeth were restored temporarily. Postoperatively, the patients were prescribed ibuprofen 400 mg, to be taken if required. Pain experience and analgesic intake were recorded for 7 days following chemomechanical preparation. The data were analysed using Mann-Whitney U-test and chi-square tests. Pain experience was higher with foraminal enlargement than when using a conventional technique. A significant difference was observed in postoperative pain during the first 4 days and the sixth day (P  0.05). Enlargement of the apical foramen during root canal treatment increased the incidence and intensity of postoperative pain. © 2015 International Endodontic Journal. Published by John Wiley & Sons Ltd.

The Globe: Exhibitions and Events

CERN Multimedia

2007-01-01

Globe of Science and Innovation Route de Meyrin, 1211 Geneva Conference Nano materials: small dimensions, big opportunities Thursday 22 November at 8.00 p.m. Christoph Renner, Professor of Physics and Deputy Director of MaNEP*Information technologies have developed at an incredible pace over the past sixty years. Mobile phones, MP3 players and other modern gizmos are infinitely more powerful than the first computers, which took up whole rooms! The main driving force behind this evolutionary process has been the boom in the miniaturisation of electronic components. The latest technological innovations have led to a new range of tools being developed, allowing matter to be visualised, manipulated and characterised at the smallest possible scales, molecule by molecule and even atom by atom. At these scales, the behaviour of matter is altered as the conventional properties of mass are gradually taken over by quantum effects with which we are quite unfamiliar in our everyday li...

Sustainability debate at the Globe

CERN Multimedia

Joannah Caborn Wengler

2012-01-01

Eco-neighbourhoods, solar panels, recycled heat: these were just some of the innovative ecological projects presented at the panel discussion organised by the Commune of Meyrin at the Globe on Thursday 21 June. CERN is closely involved with several of the projects.   CERN has an important role to play in sustainable development, and in Meyrin it has an excellent local partner. This was perhaps the key message, from CERN’s point of view, to come out of Thursday’s event. It particularly highlighted the proposed plan to use part of the “waste” heat going to the cooling towers at Point 1 to contribute to heating Meyrin’s new ecological housing project, Les Vergers. Some of CERN’s other high-profile contributions to sustainable development, such as the solar panels using CERN vacuum technology on the airport roof, were also presented. The video below presents some of the main ideas and actors in the CERN-Meyrin partnership. Please note that t...

Literatur zu Gast im Globe

CERN Multimedia

2006-01-01

Der deutsche Schriftsteller Thomas LEHR liest am 23. März 2006 aus seinem Roman '42', einem philosophischen Abenteuerroman über die Suche nach der Zeit, erzählt in einer funkelnden und souveränen Sprache. Eine Welt von vernichtender Schönheit und bizarren Schrecken wartet auf eine Besuchergruppe, die in der Nähe von Genf die unterirdischen Anlagen des Forschungszentrums für Teilchenphysik CERN besichtigt. Als sie um 12:47:42 wieder ans Tageslicht tritt, scheint ganz Europa in einen Dornröschenschlaf gefallen. Allein die 70 Besucher können sich noch bewegen. Monate und Jahre verharrt die Welt wie in einer riesigen dreidimensionalen Fotografie, bis ein wiederum schockierendes Ereignis die 'Chronifizierten' aus ihren physikalischen Spekulationen und seltsamen Lebensformen reisst. Zu dieser literarischen Veranstaltung im 'Globe of Science and Innovation' laden gemeinsam das Generalkonsulat der Bundesrepublik Deutschland in Genf und CERN ein. Vor Beginn der Lesung wird eine Führung in deutscher Sprac...

Live broadcast from the Globe

CERN Multimedia

La tête au carréTuesday, 17 June 2008 between 2.00 and 3.00 p.m.“La tête au carré”, a France Inter radio programme devoted to science, will set up its sound booth at CERN for a special broadcast on the LHC.The journalist Mathieu Vidard will interview the following guests: - Pierre Van Hove, an experimental physicist working on CMS. He is a CNRS research scientist from the Institut Hubert Curien in Strasbourg, France.- Abdelhak Djouadi is a theoretical physicist. He is a research director at the CNRS’s Laboratoire de physique théorique at Orsay, France and holder of the CNRS silver medal.- Magali Gruwe, one of the engineers in charge of LHC operations at CERN.» To take part in this live broadcast, which is open to the public, come to the Globe at 1:30 p.m. The number of places is limited.» No specialist knowledge required.» See the programme's homepage

2008 events in the Globe

CERN Multimedia

2008-01-01

Globe of Science and Innovation 1st floor - Route de Meyrin, 1211 Geneva Interactive exhibition Superconductivity—magical attraction From Tuesday, 28 October, to Saturday, 13 December 2008 Tuesdays and Wednesdays from 2.00 p.m. to 5.30 p.m. Saturdays from 9 a.m. to 5.00 p.m. The phenomenon of superconductivity was discovered a century ago. The first step was taken in 1907 when helium was liquefied for the first time. The capability to cool materials down to temperatures of -269°C (4.2K), made it possible to study the new phenomenon of superconductivity. The properties of this amazing discovery are already being used in a variety of applications in such areas as medical imaging, energy transportation, storage, magnetic levitation and transportation, and electronics. Come and find out how superconductivity has been used for the magnets of CERN’s new accelerator, and test the feeling of levitation for yourself! Free entry - No specialist knowledge required. Fête de ...

2008 events in the Globe

CERN Multimedia

2008-01-01

Globe of Science and Innovation 1st floor - Route de Meyrin, 1211 Geneva Interactive exhibitionSuperconductivity—magical attraction From Tuesday, 28 October, to Saturday, 13 December 2008 Tuesdays and Wednesdays from 2.00 p.m. to 5.30 p.m. Saturdays from 9 a.m. to 5.00 p.m. The phenomenon of superconductivity was discovered a century ago. The first step was taken in 1907 when helium was liquefied for the first time. The capability to cool materials down to temperatures of -269°C (4.2K), made it possible to study the new phenomenon of superconductivity. The properties of this amazing discovery are already being used in a variety of applications in such areas as medical imaging, energy transportation, storage, magnetic levitation and transportation, and electronics. Come and find out how superconductivity has been used for the magnets of CERN’s new accelerator, and test the feeling of levitation for yourself! Free entry - No specialist knowledge required. In mathema...

The Globe: Exhibitions and Events

CERN Multimedia

2007-01-01

The LHC, accelerator of scienceCERN is soon to commission the world’s most powerful accelerator, the LHC (Large Hadron Collider), which will provide us with new insights into the Universe and how it evolved. This series of lectures is all about understanding the scientific and technological challenges of this phenomenal project and assessing its innovations through their everyday applications. Come and take a sneak preview of the LHC! Thursday 29 November, 8:00 p.m. Share: leading-edge technology at the service of society Jean-Marie Le Goff, physicist and head of technology transfer at CERN The technologies used by the LHC are already finding applications in other scientific fields, such as medicine, climatology, metrology and computer science. Through its ground-breaking technologies, particle physics benefits society as a whole.>>>> Lectures are free and require no specialist knowledge. In French.>>> By reservation only: tel. +41 (0)22 767 76 76 http://globe.web.cern.c...

A case of the persistence of the primitive hypoglossal artery with an enlarged hypoglossal canal

International Nuclear Information System (INIS)

Tomura, Noriaki; Inugami, Atsushi; Uemura, Kazuo; Asakura, Ken

1987-01-01

A case of the persistence of the primitive hypoglossal artery is reported, with a roentgenographic demonstration of the enlarged hypoglossal canal. A 63-year-old man was admitted to this hospital as a result of a malfunction of the ventriculo-peritoneal shunt. At the age of 51, the patient had been operated on in this hospital for an aneurysm of the right middle cerebral artery; at that time, the right primitive hypoglossal artery was observed on right carotid angiograms. On the day following admission, bilateral retrograde vertebral angiography was performed and the right persistent primitive hypoglossal artery was recognized again. Stenvers views of the skull demonstrated an enlargement of the hypoglossal canal, with a smooth sclerotic rim. High-resolution computed tomography with a contrast infusion delineated the right primitive hypoglossal artery through the enlarged hypoglossal canal. The diameter of the enlarged right hypoglossal canal and that of the left one were found to be 8 mm and 4 mm respectively on the CT. When an enlargement of the hypoglossal canal with a sclerotic rim is observed, the persistence of the primitive hypoglossal artery should be considered in the differential diagnosis. (author)

Enlarged thalamostriate vein causing unilateral Monro foramen obstruction. Case report.

Science.gov (United States)

Leonardo, Jody; Grand, Walter

2009-06-01

Causes of unilateral hydrocephalus resulting from an obstruction at the Monro foramen include foraminal atresia, tumors, gliosis, contralateral shunting, and infectious and inflammatory conditions. However, few reports in the literature cite vascular lesions as the cause of the obstruction. To their knowledge, the authors present the first report of unilateral hydrocephalus occurring due to an abnormally enlarged thalamostriate vein independent of an arteriovenous malformation or developmental venous angioma. The condition was treated successfully by endoscopic septum pellucidum fenestration. A 28-year-old man was referred for evaluation due to a 10-year history of chronic headaches that worsened in severity over the past year. A CT scan of the head revealed unilateral right ventricular dilation. Cranial MR imaging with and without contrast administration showed a dilated right thalamostriate-internal vein complex without any evidence of associated arteriovenous malformation or venous angioma. Endoscopic exploration of the right lateral ventricle showed an enlarged subependymal thalamostriate vein obstructing the Monro foramen. An endoscopic fenestration of the septum pellucidum was performed, resulting in alleviation of the patient's symptoms. Abnormally enlarged venous structures may cause obstructive unilateral hydrocephalus and can be a rare cause of chronic, intermittent headaches in adults. Endoscopic fenestration of the septum pellucidum is an effective treatment.

Long term follow up of idiopathic gingival enlargement associated with chronic periodontitis: A case report and review.

Science.gov (United States)

Nagarale, Girish P; Ravindra, S; Thakur, Srinath; Setty, Swati

2013-03-01

Idiopathic gingival enlargement is a rare condition characterized by massive enlargement of the gingiva. It may be associated with other diseases/conditions characterizing a syndrome, but rarely associated with periodontitis. This case report describes an unusual clinical form of gingival enlargement associated with chronic periodontitis. Clinical examination revealed diffuse gingival enlargement. The lesion was asymptomatic, firm, and pinkish red. Generalized periodontal pockets were observed. Radiographic evaluation revealed generalized severe alveolar bone loss. Histopathological investigations revealed atrophic epithelium with dense fibrocollagenous tissue. Lesions healed successfully following extraction and surgical excision, and no recurrence was observed after 1 year follow-up but recurrence was observed at 3 and 5-years follow-up. Successful treatment of idiopathic gingival enlargement depends on proper identification of etiologic factors and improving esthetics and function through surgical excision of the over growth. However, there may be recurrence.

On filament structure and propagation within a commercial plasma globe

International Nuclear Information System (INIS)

Burin, M. J.; Simmons, G. G.; Ceja, H. G.; Zweben, S. J.; Nagy, A.; Brunkhorst, C.

2015-01-01

The filamentary discharge seen within commercial plasma globes is commonly enjoyed yet not well understood. Here, we investigate the discharge properties of a plasma globe using a variable high voltage amplifier. We find that increasing voltage magnitude increases the number of filaments while leaving their individual structure basically unchanged, a result typical of dielectric barrier discharges. The frequency of the voltage also affects filament population but more significantly changes filament structure, with more diffuse filaments seen at lower frequencies. Voltage polarity is observed to be important, especially at lower frequencies, where for negative-gradient voltages the discharge is more diffuse, not filamentary. At late stages of the discharge circular structures appear and expand on the glass boundaries. We find no trend of discharge speed with respect to voltage variables, though this may be due to manufacturer sample-to-sample variation. Each voltage cycle the discharge expands outward at ∼10–15 km/s, a speed significantly higher than the estimated electron drift yet considerably lower than that observed for most streamers. We discuss the physics of these observations and their relation to similar discharges that can be found within nature and industry

Amygdala and Hippocampus Enlargement during Adolescence in Autism

Science.gov (United States)

Groen, Wouter; Teluij, Michelle; Buitelaar, Jan; Tendolkar, Indira

2010-01-01

Objective: The amygdala and hippocampus are key components of the neural system mediating emotion perception and regulation and are thought to be involved in the pathophysiology of autism. Although some studies in children with autism suggest that there is an enlargement of amygdala and hippocampal volume, findings in adolescence are sparse.…

Estimating Wet Bulb Globe Temperature Using Standard Meteorological Measurements

International Nuclear Information System (INIS)

Hunter, C.H.

1999-01-01

The heat stress management program at the Department of Energy''s Savannah River Site (SRS) requires implementation of protective controls on outdoor work based on observed values of wet bulb globe temperature (WBGT). To ensure continued compliance with heat stress program requirements, a computer algorithm was developed which calculates an estimate of WBGT using standard meteorological measurements. In addition, scripts were developed to generate a calculation every 15 minutes and post the results to an Intranet web site

Acceleration-enlarged symmetries in nonrelativistic space-time with a cosmological constant TH1"-->

Science.gov (United States)

Lukierski, J.; Stichel, P. C.; Zakrzewski, W. J.

2008-05-01

By considering the nonrelativistic limit of de Sitter geometry one obtains the nonrelativistic space-time with a cosmological constant and Newton Hooke (NH) symmetries. We show that the NH symmetry algebra can be enlarged by the addition of the constant acceleration generators and endowed with central extensions (one in any dimension (D) and three in D=(2+1)). We present a classical Lagrangian and Hamiltonian framework for constructing models quasi-invariant under enlarged NH symmetries that depend on three parameters described by three nonvanishing central charges. The Hamiltonian dynamics then splits into external and internal sectors with new noncommutative structures of external and internal phase spaces. We show that in the limit of vanishing cosmological constant the system reduces to the one, which possesses acceleration-enlarged Galilean symmetries.

Enlargement of the European Union and agricultural policy reform

DEFF Research Database (Denmark)

Jensen, Maria Skovager; Lind, Kim Martin Hjorth; Zobbe, Henrik

2009-01-01

A connection exists between enlargement of the European Union and reforms of the Common Agricultural Policy (CAP). Based upon rational choice theory, we examine whether the member states’ CAP positions are related to structures in their agricultural sectors. The overall hypothesis...

Analysis of reforming process of large distorted ring in final enlarging forging

International Nuclear Information System (INIS)

Miyazawa, Takeshi; Murai, Etsuo

2002-01-01

In the construction of reactors or pressure vessels for oil chemical plants and nuclear power stations, mono block open-die forging rings are often utilized. Generally, a large forged ring is manufactured by means of enlarging forging with reductions of the wall thickness. During the enlarging process the circular ring is often distorted and becomes an ellipse in shape. However the shape control of the ring is a complicated work. This phenomenon makes the matter still worse in forging of larger rings. In order to make precision forging of large rings, we have developed the forging method using a v-shape anvil. The v-shape anvil is geometrically adjusted to fit the distorted ring in the final circle and reform automatically the shape of the ring during enlarging forging. This paper has analyzed the reforming process of distorted ring by computer program based on F.E.M. and examined the effect on the precision of ring forging. (author)

How Cool was the Eclipse? Atmospheric Measurements and Citizen Science via NASA's GLOBE Observer

Science.gov (United States)

Weaver, K. L. K.; Riebeek Kohl, H.

2017-12-01

The solar eclipse of 2017 presented an extraordinary opportunity to engage the public in shared science activity across the entire United States. While a natural focus of the eclipse was on astronomy and heliophysics, there was also an opening for excellent connections to Earth science. Because of the excitement of the event, many people gathered for long periods before and after totality, a perfect opportunity for observations and data collection to explore the impact of the eclipse on the atmosphere. The data was collected via NASA's GLOBE Observer app, a subset of the Global Learning and Observations to Benefit the Environment Program, a citizen science project which has been active for more than 20 years training teachers to collect many different types of environmental science data with their students. GLOBE Observer expands that audience to citizen scientists who might not be connected to a school, but are still interested in collecting data. In addition to the clouds observations that are normally part of GLOBE Observer, a special temporary protocol was added for the eclipse to include air temperature. Both types of measurements were collected at regular intervals for several hours before and after the point of maximum eclipse. By crowdsourcing data from all across the United States, on and off the path of totality, the hope was to be able to see patterns that wouldn't be apparent with fewer data points. In particular, there are few sources of detailed cloud data from the ground, including cloud type as well as overall cloud cover, especially as collected during a unique natural experiment such as an eclipse. This presentation will report preliminary results of the GLOBE Observer eclipse citizen science project, including participation totals and impact, data site distribution, as well as early analyses of both temperature and cloud data.

The International Globe at Night Citizen-Science Campaign: Shedding Light on Light Pollution

Science.gov (United States)

Walker, C. E.; Pompea, S. M.

2013-12-01

For 8 years now, the Globe at Night campaign has invited citizen-scientists worldwide to measure and record the brightness of their night sky by hunting for the faintest stars in a particular constellation. Students for science projects and scientists for research use the data to monitor levels of brightness or 'light pollution' around the world. They also use the Globe at Night data to understand light pollution's effects on energy consumption, plants, wildlife and human health, as well as our ability to enjoy a starry night sky. The dates of the campaign for 2014 have been extended to every month during the year. Ten days each month (when the Moon is not up between 8pm and 10pm) are the recommended times to take measurements for the campaign. However, one can participate at other times and dates, as long as the Moon is not in the night sky and it is more than an hour after sunset or more than an hour before sunrise. New in 2014 will be an Android app that will allow you to input visual measurements anytime the Moon is not up. Also possibly included will be an iPhone app that will take sky brightness measurements. The campaign dates and the 5 easy steps to participating in the campaign are listed at www.globeatnight.org. You do not need to register. Once on the report page, you enter your location, date and time (automatic for a smart device). You find the constellation of the month in the night sky. (Help is on the website.) Then you choose which chart looks most like what you see toward the constellation. Choose the icon for how clear or cloudy it is and hit the submit button and you are done! The fifth step is returning later to the website to compare your observations on the world map to others from around the globe. Included on the Globe at Night website are many helpful resources and tools from finding the constellations used in the campaign, to understanding concepts like light pollution, to games that test your expertise in choosing 'limiting magnitudes

A Rare Case Report of Amlodipine-Induced Gingival Enlargement and Review of Its Pathogenesis

Directory of Open Access Journals (Sweden)

Sanjeev Joshi

2013-01-01

Full Text Available Gingival enlargement is a common clinical feature of gingival and periodontal diseases. It is an unwanted side effect of certain systemic drugs given for nondental treatment. It is being reported with three main groups of drugs like calcium channel blockers (CCBs, immunosuppressants, and anticonvulsants. Among calcium channel blockers, nifedipine causes gingival hyperplasia in about 10% of patients, whereas the incidence of amlodipine-, a third generation calcium channel blocker, induced gingival hyperplasia is very limited. There are very few reports of amlodipine-induced gingival enlargement at a dose of 5 mg. We report a case of amlodipine-induced gingival enlargement in a 45-year-old hypertensive patient taking amlodipine at a dose of 5 mg.

Long term follow up of idiopathic gingival enlargement associated with chronic periodontitis: A case report and review

Directory of Open Access Journals (Sweden)

Girish P Nagarale

2013-01-01

Full Text Available Background: Idiopathic gingival enlargement is a rare condition characterized by massive enlargement of the gingiva. It may be associated with other diseases/conditions characterizing a syndrome, but rarely associated with periodontitis. Case Description: This case report describes an unusual clinical form of gingival enlargement associated with chronic periodontitis. Clinical examination revealed diffuse gingival enlargement. The lesion was asymptomatic, firm, and pinkish red. Generalized periodontal pockets were observed. Radiographic evaluation revealed generalized severe alveolar bone loss. Histopathological investigations revealed atrophic epithelium with dense fibrocollagenous tissue. Lesions healed successfully following extraction and surgical excision, and no recurrence was observed after 1 year follow-up but recurrence was observed at 3 and 5-years follow-up. Clinical Implications: Successful treatment of idiopathic gingival enlargement depends on proper identification of etiologic factors and improving esthetics and function through surgical excision of the over growth. However, there may be recurrence.

Coming of spring in Europe and on Day Night Year Globe

Science.gov (United States)

Marković-Topalović, Tatjana; Božić, Mirjana; Stojićević, Goran

2014-05-01

Day and night cycles, change of seasons, secular variations of climate on Earth are phenomena that depend on insolation of the Earth, its internal rotation and the orientation of its axis with respect to the Sun. For teaching about these phenomena, we have been using, since 2011, the outdoor globe that has the same orientation in space as the Earth. We call it Day Night Year Globe (DING). It was erected in the Center for advanced education of teachers in Šabac, Serbia [1]. Such globes were also erected in the Weizmann Institute in Israel, near the Max Valier Observatory in Italy, in the courtyard of the Tre University in Rome, in the Science Park in Zurich. During 2010 and 2011, the High Medical School took part and coordinated the realization of the Greenwave project [2] in the Šabac region. Twenty-two teachers, in seven primary schools, inspired and instructed their students to observe how exactly spring arrives and moves across Europe. Their task was to measure on daily basis: wind speed, temperature and rain precipitation. They also recorded sightings of species (barn swallow and frog spawns), common to all European countries, and of local species, which act as early indicators of the arrival of spring. The scientific contribution of the Šabac team consisted of correlating these observations and observations of changes of illumination on DING. During one sunny day, students observe the mapping of Earth's daily rotation onto DING. By observing the circle of illumination, day by day, students see how the inclination of this circle changes during the year. At the spring equinox the circle of illumination lies along the meridian. Our idea was that participants in other country could incorporate observations on DING, or a hands-on globe with two-rotation axes, properly oriented. We tried to induce interest for this idea to the authors and leaders of the Greenwave project. In Milanković's theory of the climate change of Earth, the orientation of Earth's axis with

Disappearance of enlarged nuchal translucency before 14 weeks' gestation: relationship with chromosomal abnormalities and pregnancy outcome.

Science.gov (United States)

Müller, M A; Pajkrt, E; Bleker, O P; Bonsel, G J; Bilardo, C M

2004-08-01

The aim of this study was to investigate the natural course of enlarged nuchal translucency (NT) and to determine if its disappearance before 14 weeks' gestation is a favorable prognostic sign in relation to fetal karyotype and pregnancy outcome. A total of 147 women with increased NT (> 95th centile) at first measurement were included in this study. A second measurement was performed in all cases, at an interval of at least 2 days. Both measurements were taken between 10 + 3 and 14 + 0 weeks. All women underwent chorionic villus sampling or amniocentesis for subsequent karyotyping. In those women with a normal karyotype, a fetal anomaly scan was performed at 20 weeks' gestation. Pregnancy outcome was recorded in all cases. The finding of persistent or disappearing NT enlargement was analyzed in relation to fetal karyotype and pregnancy outcome. Of the 147 paired measurements, NT remained enlarged at the second measurement in 121 (82%) cases. An abnormal karyotype was found in 35% of these cases. In 26 (18%) fetuses the NT measurement was found to be below the 95th percentile at the second measurement and in only two of them an abnormal karyotype was found (8%). In the 103 chromosomally normal fetuses an adverse outcome (i.e. fetal loss or structural defects) was recorded in 22 fetuses with persistent enlargement (28%) and in four fetuses with disappearing enlargement (17%). Disappearance of an enlarged NT before 14 weeks' gestation is not a rare phenomenon and seems to be a favorable prognostic sign with respect to fetal karyotype. Overall, no significant difference in pregnancy outcome was found between chromosomally normal fetuses with persisting or disappearing NT enlargement. Copyright 2004 ISUOG

Enlargement of lumbar spinal canal in lumbar degenerative spondylolisthesis. Evaluation with three-dimensional computed tomography

International Nuclear Information System (INIS)

Kunishi, Yoshihiko

2003-01-01

A number of clinical studies have demonstrated that enlargement of the lumbar spinal canal is one of the effective surgical procedures for the treatment of the lumbar degenerative spondylolisthesis and provides a good result. In the present study, we have evaluated the long-term outcome of the enlargement of the lumbar canal without fusion in thirty eight patients with lumbar degenerative spondylolisthesis using three-dimensional computed tomography (3D-CT) The improvement rate was excellent in 80% of the patients (mean improvement ratio, 83%) according to the Japanese Orthopedic Association scoring system. We found that the sufficient enlargement of the canal was obtained by the surgery and maintained for a long period of time. The results from 3D-CT suggested that a round shape was maintained in the canal after the surgery because of pressures of the dura mater against to the bony canal. None of patients showed lumbar instability. In conclusion, enlargement of lumbar canal without fusion is useful for the treatment of lumbar degenerative spondylolisthesis, and the enlarged canal has been maintained for a long period of time after the surgery. The results demonstrated the clinical utility of 3D-CT to evaluate the preoperative and postoperative shape of the spine. (author)

Wellbore enlargement investigation: Potential analogs to the Waste Isolation Pilot Plant during inadvertent intrusion of the repository

International Nuclear Information System (INIS)

Boak, D.M.; Dotson, L.; Aguilar, R.

1997-01-01

This study involved the evaluation and documentation of cases in which petroleum wellbores were enlarged beyond the nominal hole diameter as a consequence of erosion during exploratory drilling, particularly as a function of gas flow into the wellbore during blowout conditions. A primary objective was to identify analogs to potential wellbore enlargement at the Waste Isolation Pilot Plant (WIPP) during inadvertent human intrusion. Secondary objectives were to identify drilling scenarios associated with enlargement, determine the physical extent of enlargement, and establish the physical properties of the formation in which the enlargement occurred. No analogs of sufficient quality to establish quantitative limits on wellbore enlargement at the WIPP disposal system were identified. However, some information was obtained regarding the frequency of petroleum well blowouts and the likelihood that such blowouts would bridge downhole, self-limiting the surface release of disposal-system material. Further work would be necessary, however, to determine the conditions under which bridging could occur and the extent to which the bridging might be applicable to WIPP. In addition, data on casing sizes of petroleum boreholes in the WIPP vicinity support the use of a 12-1/4 inch borehole size in WIPP performance assessment calculations. Finally, although data are limited, there was no evidence of significant wellbore enlargement in any of three blowouts that occur-red in wellbores in the Delaware Basin (South Culebra Bluff Unit No. 1, Energy Research and Development Administration (ERDA) 6, and WIPP 12)

Dissolution-Enlarged Fractures Imaging Using Electrical Resistivity Tomography (ERT)

Science.gov (United States)

Siami-Irdemoosa, Elnaz

In recent years the electrical imaging techniques have been largely applied to geotechnical and environmental investigations. These techniques have proven to be the best geophysical methods for site investigations in karst terrain, particularly when the overburden soil is clay-dominated. Karst is terrain with a special landscape and distinctive hydrological system developed by dissolution of rocks, particularly carbonate rocks such as limestone and dolomite, made by enlarging fractures into underground conduits that can enlarge into caverns, and in some cases collapse to form sinkholes. Bedding planes, joints, and faults are the principal structural guides for underground flow and dissolution in almost all karstified rocks. Despite the important role of fractures in karst development, the geometry of dissolution-enlarged fractures remain poorly unknown. These features are characterized by an strong contrast with the surrounding formations in terms of physical properties, such as electrical resistivity. Electrical resistivity tomography (ERT) was used as the primary geophysical tool to image the subsurface in a karst terrain in Greene County, Missouri. Pattern, orientation and density of the joint sets were interpreted from ERT data in the investigation site. The Multi-channel Analysis of Surface Wave (MASW) method and coring were employed to validate the interpretation results. Two sets of orthogonal visually prominent joints have been identified in the investigation site: north-south trending joint sets and west-east trending joint sets. However, most of the visually prominent joint sets are associated with either cultural features that concentrate runoff, natural surface drainage features or natural surface drainage.

Hearing loss and enlarged internal auditory canal in children.

Science.gov (United States)

Santos, Saturnino; Domínguez, M Jesús; Cervera, Javier; Suárez, Alicia; Bueno, Antonio; Bartolomé, Margarita; López, Rafael

2014-01-01

Among the temporal bone abnormalities that can be found in the etiological study of paediatric sensorineural hearing loss (SNHL) by imaging techniques, those related to the internal auditory canal (IAC) are the least frequent. The most prevalent of these abnormalities that is associated with SNHL is stenotic IAC due to its association with cochlear nerve deficiencies. Less frequent and less concomitant with SNHL is the finding of an enlarged IAC (>8mm). Retrospective and descriptive review of clinical associations, imaging, audiological patterns and treatment of 9 children with hearing loss and enlarged IAC in the period 1999 to 2012. Two groups of patients are described. The first, without association with vestibulocochlear dysplasias, consisted of: 2 patients with SNHL without other temporal bone or systemic abnormalities, one with bilateral mixed HL from chromosome 18q deletion, one with a genetic X-linked DFN3 hearing loss, one with unilateral hearing loss in neurofibromatosis type 2 with bilateral acoustic neuroma, and one with unilateral hearing loss with cochlear nerve deficiency. The second group, with association with vestibulocochlear dysplasias, was comprised of: one patient with moderate bilateral mixed hearing loss in branchio-oto-renal syndrome, one with profound unilateral SNHL with recurrent meningitis, and another with profound bilateral SNHL with congenital hypothyroidism. The presence of an enlarged IAC in children can be found in different clinical and audiological settings with relevancies that can range from life-threatening situations, such as recurrent meningitis, to isolated hearing loss with no other associations. Copyright © 2013 Elsevier España, S.L. All rights reserved.

THE IMPACT OF EU ENLARGEMENT ON THE RUSSIAN FEDERATION

Directory of Open Access Journals (Sweden)

Alfred E. Kellermann

2004-10-01

Full Text Available EU Enlargement is a consequence of the success story of the creation of the European Communities, as many applicant countries were attracted to the new legal order based on the rule of law, rather than to an order or disorder based on the rule of politics. As from May 1st 2004, the EU enlargement, unprecedented in its size, marks a historic milestone for the European Union and its Member States, and also for the whole continent. Given this new context, the EU has to find and define new cooperation partnerships with its neighbours. A major partner, not to be neglected in this new policy is by all means Russia. The first Summit between the enlarged EU and Russia held in Moscow on 21 May 2004 was the first high-level meeting of the 25 EU and Russia following the successful conclusion of negotiations between the European Commission and Russia on the extension of the EU-Russia Partnership and Cooperation Agreement (PCA to the ten new EU Member States. The Summit calls for the reinforcement of EU-Russia relations via the creation of Four Common Spaces: a common economic space (with specific reference to environment and energy; a common space of Freedom, Security and Justice; a field of external security; as well as a space of research and education including culture. The next step will be to define shared priorities and concrete measures for each of the Four Common Spaces in a mutually agreed Action Plan.

The Fungal Defensin Family Enlarged

Directory of Open Access Journals (Sweden)

Jiajia Wu

2014-08-01

Full Text Available Fungi are an emerging source of peptide antibiotics. With the availability of a large number of model fungal genome sequences, we can expect that more and more fungal defensin-like peptides (fDLPs will be discovered by sequence similarity search. Here, we report a total of 69 new fDLPs encoded by 63 genes, in which a group of fDLPs derived from dermatophytes are defined as a new family (fDEF8 according to sequence and phylogenetic analyses. In the oleaginous fungus Mortierella alpine, fDLPs have undergone extensive gene expansion. Our work further enlarges the fungal defensin family and will help characterize new peptide antibiotics with therapeutic potential.

Design, Development, and Maintenance of the GLOBE Program Website and Database

Science.gov (United States)

Brummer, Renate; Matsumoto, Clifford

2004-01-01

This is a 1-year (Fy 03) proposal to design and develop enhancements, implement improved efficiency and reliability, and provide responsive maintenance for the operational GLOBE (Global Learning and Observations to Benefit the Environment) Program website and database. This proposal is renewable, with a 5% annual inflation factor providing an approximate cost for the out years.

Variation of Phenolic Content in Globe Artichoke in Relation to Biological, Technical and Environmental Factors

Directory of Open Access Journals (Sweden)

Sara Lombardo

2009-12-01

Full Text Available In Italy, globe artichoke production is prevailingly concentrated in the South and islands, where it provides an important contribution to the agricultural economy. In recent years, there has been a renewed interest in this crop as a promising source of polyphenols, a heterogeneous class of secondary metabolites characterized by various healthy properties well-documented in literature. The phenolic fraction, present in the different artichoke plant parts, varies widely in relation to biotic and abiotic factors. Therefore, the present study aimed at evaluating the variation of phenolic content in globe artichoke in relation to biological, technical and environmental factors. Two field-experiments were carried out in Sicily (South Italy in two representative cultivation areas, in order to examine the effects of genotype, head fraction, season conditions, planting density and arrangement on the globe artichoke phenolic concentration. Both the total polyphenols and the individual phenolic compounds detected were notably genotype- dependent. Particularly, the high level of caffeoylquinic acids (chlorogenic acid, among others and apigenin 7- O-glucuronide, reported respectively by “Violetto di Sicilia” and “Romanesco clone C3”, could be used to encourage globe artichoke fresh consumption. Total polyphenols content also resulted more abundant in specific accumulation sites within the inflorescence, such as the floral stem and receptacle, and for most of genotypes it decreased during the second year in response to the different meteorological conditions. Additionally, total polyphenols content significantly and linearly increased as plant density increased from 1.0 to 1.8 plant m-2 and it significantly increased by 13% passing from single to twin rows plant arrangement.

Variation of Phenolic Content in Globe Artichoke in Relation to Biological, Technical and Environmental Factors

Directory of Open Access Journals (Sweden)

Giovanni Mauromicale

2011-02-01

Full Text Available In Italy, globe artichoke production is prevailingly concentrated in the South and islands, where it provides an important contribution to the agricultural economy. In recent years, there has been a renewed interest in this crop as a promising source of polyphenols, a heterogeneous class of secondary metabolites characterized by various healthy properties well-documented in literature. The phenolic fraction, present in the different artichoke plant parts, varies widely in relation to biotic and abiotic factors. Therefore, the present study aimed at evaluating the variation of phenolic content in globe artichoke in relation to biological, technical and environmental factors. Two field-experiments were carried out in Sicily (South Italy in two representative cultivation areas, in order to examine the effects of genotype, head fraction, season conditions, planting density and arrangement on the globe artichoke phenolic concentration. Both the total polyphenols and the individual phenolic compounds detected were notably genotype- dependent. Particularly, the high level of caffeoylquinic acids (chlorogenic acid, among others and apigenin 7- O-glucuronide, reported respectively by “Violetto di Sicilia” and “Romanesco clone C3”, could be used to encourage globe artichoke fresh consumption. Total polyphenols content also resulted more abundant in specific accumulation sites within the inflorescence, such as the floral stem and receptacle, and for most of genotypes it decreased during the second year in response to the different meteorological conditions. Additionally, total polyphenols content significantly and linearly increased as plant density increased from 1.0 to 1.8 plant m-2 and it significantly increased by 13% passing from single to twin rows plant arrangement.

Report on the 2016 conference Tax Treaty Case Law Around the Globe

NARCIS (Netherlands)

van Hulten, Mart; Jallai, Ave-Geidi

2016-01-01

Each year the international conference Tax Treaty Case Law Around the Globe provides a forum to discuss with outstanding experts of the relevant jurisdictions the most important and interesting tax treaty cases which recently have been decided all over the world. This article provides a report on

2009 events in the Globe

CERN Multimedia

2009-01-01

Globe of Science and Innovation 1st floor - Route de Meyrin, 1211 Geneva Mini-Einstein: physics for totsWednesdays from 14:30 to 15:30 January 2009: 14, 21, 28 and February 2009: 11, 18, 25 CERN is offering a series of workshops designed to teach the ABC of physics to the very young. Games and hands-on activities based on notions such as weight and waves will stimulate the children’s curiosity and initiate them into the world of science. Workshop in French for accompanied 4-to-6-year-olds. Free of charge, please book on +41 (0)22 767 76 76 Interactive exhibition Superconductivity... magical attraction Special opening from Tuesday, 13 January, to Saturday, 31 January 2009 Tuesdays and Wednesdays from 2.00 p.m. to 5.30 p.m. and Saturdays from 9 a.m. to 5.00 p.m. Following the success at the end of last year, the exhibition "Superconductivity... magical attraction" will be extended until the end of January. The phenomenon of sup...

On stage at the Globe

CERN Document Server

2005-01-01

The Globe's first season this year is to be rounded off with two shows that are in perfect keeping with the centenary of the death of Jules Verne and Albert Einstein's theory of relativity. 'Signé Jules Verne' (Signed Jules Verne) The Miméscope company, which has already thrilled audiences at CERN with shows such as the 'Oracle of Delphi' and, more recently, 'Point de Suspension', returns with an interactive show entitled 'Signé Jules Verne'. Imagine a slightly crazy machine, which rolls along on wheels, floats, flies or moves in any other way you like, as long as it works on scientific principles. This is the task that Jules Verne sets his audience. Experiments, models, drawings, blueprints, he's interested in them all. In its typical style, Miméscope has created a world of enchantment that combines theatre, choreography, music and lighting effects in a show that evolves as a function of its audience. Performances at 3.00 p.m. on 4, 7, 10 and 11 December An interactive show for the general public...

Gene–Environment Correlation Underlying the Association Between Parental Negativity and Adolescent Externalizing Problems

Science.gov (United States)

Marceau, Kristine; Horwitz, Briana N.; Ganiban, Jody M.; Reiss, David; Narusyte, Jurgita; Spotts, Erica L.; Neiderhiser, Jenae M.

2014-01-01

Studies of adolescent or parent-based twins suggest that gene–environment correlation (rGE) is an important mechanism underlying parent–adolescent relationships. However, information on how parents′ and children’s genes and environments influence correlated parent and child behaviors is needed to distinguish types of rGE. The present study used the novel Extended Children of Twins model to distinguish types of rGE underlying associations between negative parenting and adolescent (age 11–22 years) externalizing problems with a Swedish sample of 909 twin parents and their adolescent offspring and a U.S.-based sample of 405 adolescent siblings and their parents. Results suggest that evocative rGE, not passive rGE or direct environmental effects of parenting on adolescent externalizing, explains associations between maternal and paternal negativity and adolescent externalizing problems. PMID:23573986

[Non-neoplastic enlargement of salivary glands: clinico-histologic analysis].

Science.gov (United States)

González Guevara, Martha Beatriz; Torres Tejero, Marco Antonio; Martínez Mata, Guillermo

2005-01-01

We carried out a retrospective study on non-neoplastic enlargement of the salivary glands at the Oral Histopathology Diagnostic Center of the Autonomous Metropolitan University at Xochimilco (UAM-Xochimilco) in Mexico during a period of 24 years (1979-2003). From 5,625 biopsies received and analyzed, a total of 461 (8.2%) were non-neoplastic enlargement of the salivary glands; for each case, we registered demographic data as well as clinic characteristics. These lesions were characterized as a heterogeneous group of pathologic entities among which we included local, obstructive, infectious, and immunopathologic lesions. The most frequent lesion was the extravasation cyst in 341 (74%) cases, followed by chronic sialoadenitis and Sjögren's syndrome with 54 (11.7%) and 41 (8.8%) cases, respectively, and at a lesser percentage mucous retention cyst, sialosis, benign lymphoepithelial lesions and those related with sialolytes. Females were affected more frequently; mean age was second to third life decades. These lesions were most frequently localized on inferior labial mucosa.

Clinical correlates of enlarged prostate size in subjects with sexual dysfunction

Directory of Open Access Journals (Sweden)

Giovanni Corona

2014-10-01

Full Text Available Digito-rectal examination (DRE of the prostate provides useful information on the state of prostate growth and on the presence of suspected peripheral nodules. The aim of this study is to describe the clinical and biochemical correlates of finding an enlarged prostate size at DRE in subjects with sexual dysfunction (SD. A consecutive series of 2379 patients was retrospectively studied. The analysis was focused on a subset of subjects (n = 1823; mean age 54.7 ± 11.4 selected for being free from overt prostatic diseases. Several parameters were investigated. After adjusting for confounders, the presence of an enlarged prostate size at DRE was associated with a higher risk of metabolic syndrome (HR = 1.346 (1.129-1.759; P = 0.030, type 2 diabetes mellitus (HR = 1.489 (1.120-1.980; P = 0.006, increased LDL cholesterol (>100 mg dl−1 ; HR = 1.354 (1.018-1.801; P = 0.037 and increased mean blood pressure (BP values (HR = 1.017 (1.007-1.027 for each mmHg increment; P = 0.001. Accordingly, enlarged prostate size was also associated with a higher risk of arteriogenic erectile dysfunction (ED, as well as with other andrological conditions, such as varicocele and premature ejaculation (PE. PSA levels were significantly higher in subjects with enlarged prostate size when compared to the rest of the sample (HR = 3.318 (2.304; 4.799 for each log unit increment in PSA levels; P < 0.0001. Arteriogenic ED, according to different criteria, was also associated with increased PSA levels. In conclusion, our data support the need to examine prostate size either by clinical (DRE or biochemical (PSA inspection in subjects with SD, in order to have insights into the nature of the SD and the metabolic and cardiovascular (CV background of the patient.

Trade integration and synchronization of shocks : implications for EU enlargement

Czech Academy of Sciences Publication Activity Database

Babetskii, Ian

2005-01-01

Roč. 13, č. 1 (2005), s. 105-138 ISSN 0967-0750 Institutional research plan: CEZ:AV0Z70850503 Keywords : EU enlargement * business cycle * trade Subject RIV: AH - Economics Impact factor: 0.774, year: 2005

Parotid enlargement in children with AIDS

International Nuclear Information System (INIS)

Soberman, N.; Leonidas, J.C.; Berdon, W.E.; Haller, J.O.; Posner, M.; Bonagura, V.

1990-01-01

PURPOSE: Painless parotid enlargement has been recently reported as a sign of AIDS, but little is known of the imaging characteristics of parotid involvement in affected children. The aim of this paper is to use US, CT and MR imaging to determine the anatomic changes of the parotid; study their possible association with pulmonary lymphoid hyperplasia (PLH); and define the immunologic parameters and clinical course. Eighteen children were evaluated clinically, radiologically, and immunologically. All patients underwent US of the parotids and chest radiography; some children had CT of the chest and MR imaging of the parotids

Accumulation of cynaropicrin in globe artichoke and localization ofenzymes involved in its biosynthesis

NARCIS (Netherlands)

Eljounaidi, K.; Comino, C.; Moglia, A.; Cankar, K.; Genre, A.; Hehn, A.; Bourgaud, F.; Beekwilder, J.; Lanteri, S.

2015-01-01

Globe artichoke (Cynara cardunculus var. scolymus) belongs to the Asteraceae family, in which one ofthe most biologically significant class of secondary metabolites are sesquiterpene lactones (STLs). Inglobe artichoke the principal STL is the cynaropicrin, which contributes to approximately 80% of

Stress energy of elastic globe in curved space and a slip-out force

International Nuclear Information System (INIS)

Sokolov, S.N.

1990-01-01

The energy of stresses in an elastic globe in the flat space and in curved space is expressed through scalar invariants of the curved space. This energy creates an additional force acting on elastic bodies in a gravitational field. 4 refs

Diagnosis Of Thyroid Enlargement: Use Of Fine Needle Aspiration ...

African Journals Online (AJOL)

One hundred and ten Fine Needle Aspiration Biopsies (FNAC) obtained from 87 patients with thyroid enlargement or nodules were retrospectively reviewed. Aspiration biopsy was accomplished using 21-gauge needle attached with 20-ml plastic syringe. There were 14 males and 73 females involved in the study. Sixty- four ...

Characteristics and significance of D-tagatose-induced liver enlargement in rats: An interpretative review.

Science.gov (United States)

Bär, A

1999-04-01

This review addresses the issue of asymptomatic liver enlargement in rats. It was necessitated by the observation of significantly increased liver weights in rats fed diets with 10 to 20% D-tagatose, a potential new bulk sweetener, for between 28 and 90 days. Increases of liver size without accompanying histopathological changes or impairment of organ function have been observed in rats in response to the ingestion of various xenobiotic compounds (including some food additives), changes of dietary composition (e.g. , high doses of fructose and sucrose), metabolic aberrations (e.g., diabetes), as well as normal pregnancy and lactation. The underlying mechanism(s) are not yet understood in detail but peroxisome proliferation, microsomal enzyme induction, increased storage of glycogen or lipids, and hyperfunction due to an excessive workload are well-established causes of hepatomegaly in rats. In D-tagatose- and fructose-fed rats, a treatment-related increase of hepatic glycogen storage was identified as a likely cause of the liver enlargement. Dietary levels of 5% and about 15-20% were determined as no-effect levels (NOEL) for D-tagatose- and fructose-induced liver enlargement, respectively. At doses above the NOEL, D-tagatose is about four times more efficient than fructose in inducing liver enlargement. On the other hand, the estimated intake of D-tagatose from its intended uses in food is about four times lower than the actual fructose intake. Consequently, a similar safety margin would apply for both sugars. Considering the similarity of the liver effects in rats of fructose, a safe food ingredient, and D-tagatose, the absence of histopathological changes in rats fed a diet with 20% D-tagatose for 90 days, and the absence of adverse long-term consequences of glycogen-induced liver enlargement in rats, it is concluded that the observed liver enlargement in D-tagatose-fed rats has no relevance for the assessment of human safety of this substance. Copyright 1999

Clinical and morphological study of calf enlargement following S-1 radiculopathy

Directory of Open Access Journals (Sweden)

Osvaldo J. M. Nascimento

1992-09-01

Full Text Available Calf enlargement following sciatica is a rare condition. It is reported the case of a 28-year-old woman who complained of repeated episodes of lower back pain radiating into the left buttock and foot. One year after the beginning of her symptoms, she noticed enlargement of her left calf. X-ray studies disclosed L5-S1 disk degeneration. EMG showed muscle denervation with normal motor conduction velocity. Open biopsies of the gastrocnemius muscles were performed. The left gastrocnemius muscle showed hypertrophic type 2 fibers in comparison with the right gastrocnemius. Electron microscopy showed mildly increased number of mitochondria in these fibers. A satisfactory explanation for denervation hypertrophy has yet to be provided.

Enhancing Science Teacher Training Using Water Resources and GLOBE

Science.gov (United States)

Falco, James W.

2002-01-01

Heritage College, located on the Yakama Indian Reservation in south central Washington state, serves a multicultural, underserved, rural population and trains teachers to staff the disadvantaged school districts on and surrounding the reservation. In-service teachers and pre-service teachers in the area show strength in biology but have weak backgrounds in chemistry and mathematics. We are addressing this problem by providing a 2-year core of courses for 3 groups of 25 students (15 pre-service and 10 in-service teachers) using GLOBE to teach integrated physical science and mathematics. At the conclusion of the program, the students will qualify for science certification by Washington State. Water resources are the focal point of the curriculum because it is central to life in our desert area. The lack or excess of water, its uses, quality and distribution is being studied by using GIS, remote sensing and historical records. Students are learning the methodology to incorporate scientific protocols and data into all aspects of their future teaching curriculum. In addition, in each of the three years of the project, pre-service teachers attended a seminar series during the fall semester with presentations by collaborators from industry, agriculture, education and government agencies. Students used NASA educational materials in the presentations that they gave at the conclusion of the seminar series. All pre- and in-service teachers continue to have support via a local web site for Heritage College GLOBE participants.

Enlargement of the iliopsoas comportment

International Nuclear Information System (INIS)

Garcia, M.; Gonzalez, J.; Martinez, A.; Garcia, M.A.; Relea, A.; Narajo, G.

1996-01-01

The iliopsoas or iliopectineal comportment is a normal structure that occasionally communicates with the synovial cavity of the hip. Rarely, in association with certain pathologies that raise the intraarticular pressure, it becomes enlarged, producing an inguinal or pelvic mass, also referred to as iliopsas bursitis. We present five cases of this pathology detected over the past year in our hospitals. Three of the patients had undergone previous vascular punctures in the hip involved, one presented brucellosis-related arthropathy and the fifth had generative joint abnormalities. The plain radiography, arthrography, ultrasound, CT,CT-guided arthrography and MR images are provided and discussed. We present an etiological factor of this process (previous vascular puncture) that has not been previously reported in the literature. 13 refs

Accumulation of cynaropicrin in globe artichoke and localization of enzymes involved in its biosynthesis.

Science.gov (United States)

Eljounaidi, K; Comino, C; Moglia, A; Cankar, K; Genre, A; Hehn, A; Bourgaud, F; Beekwilder, J; Lanteri, S

2015-10-01

Globe artichoke (Cynara cardunculus var. scolymus) belongs to the Asteraceae family, in which one of the most biologically significant class of secondary metabolites are sesquiterpene lactones (STLs). In globe artichoke the principal STL is the cynaropicrin, which contributes to approximately 80% of its characteristic bitter taste. Cynaropicrin content was assessed in globe artichoke tissues and was observed to accumulate in leaves of different developmental stages. In the receptacle, a progressive decrease was observed during inflorescence development, while the STL could not be detected in the inflorescence bracts. Almost undetectable amounts were found in the roots and inflorescence stems at the commercial stage. Cynaropicrin content was found to correlate with expression of genes encoding CcGAS, CcGAO and CcCOS, which are involved in the STL biosynthesis. A more detailed study of leaf material revealed that cynaropicrin predominantly accumulates in the trichomes, and not in the apoplastic cavity fluids. Analysis of the promoter regions of CcGAO and CcCOS revealed the presence of L1-box motifs, which confers trichome-specific expression in Arabidopsis, suggesting that cynaropicrin is not only stored but also synthesized in trichomes. A transient expression of GFP fusion proteins was performed in Nicotiana benthamiana plants: the CcGAS fluorescence signal was located in the cytoplasm while the CcGAO and CcCOS localized to the endoplasmatic reticulum. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

Enlargement gingival treatment on teeth 11 and 21

Directory of Open Access Journals (Sweden)

Umi Ghoni Tjiptoningsih

2016-12-01

Full Text Available Gingival enlargement in the interdental papillae, thickened, rounded gingival contour and discomfort became major issues that must be treated in order to be optimal appearance and function. Gingival enlargement that experienced fibrosis would not disappear with only plaque control, but required surgery that is gingivectomy and gingivoplasty. The 24-year-old woman came to the periodonsia clinic with complaints maxillary anterior gingiva swelled at teeth 11-21 with plaque index 52%. The depth of the tooth pocket 11: labial (mesial: 4, medial: 1, distal: 3. Palatal (mesial: 3, medial: 2, distal 1. The depth of the tooth pocket 21 is labial (mesial: 4, medial: 1, distal: 1, palatal (mesial: 3, medial: 1, distal 1. Gingivectomy treatment and gingivoplasty were performed with the aim of eliminating pockets and restore physiologic gingival contour which can help prevent the recurrence of the disease periodontal. In performing surgical gingivectomy and gingivoplasty, which must be considered is to minimize the disposal of gingival tissue to maintain the aesthetic, adequate access to the bone defect in order to make good corrections, and the minimization of bleeding and discomfort after surgery.

Preventive effect of aggressive blood pressure lowering on hematoma enlargement in patients with ultra-acute intracerebral hemorrhage

International Nuclear Information System (INIS)

Nishikawa, Tomofumi; Ueba, Tetsuya; Kajiwara, Motohiro; Iwata, Ryoichi; Yamashita, Kohsuke; Miyamatsu, Naomi

2010-01-01

The preventive effect of aggressive blood pressure lowering on hematoma enlargement was investigated in patients with ultra-acute spontaneous intracerebral hemorrhage (ICH). Retrospective review of 248 patients (145 males, 103 females) with spontaneous ICH treated in our hospital between 2005 and 2008 identified patients with ultra-acute ICH who were directly taken to our institute by ambulance within 3 hours after onset. Patients who could not be assessed twice by computed tomography (CT) within 24 hours after arrival were excluded. Systolic blood pressure (SBP) was aggressively controlled in all patients using intravenous nicardipine to below 140 mmHg as soon as possible after diagnosis of ICH with CT. Hematoma enlargement was defined as increase in volume of more than 33% or more than 12.5 ml in the first 24 hours. Hematoma enlargement was observed in 11 of the 73 patients (15.0%). The time course of SBP change was not significantly different in patients with and without hematoma enlargement. The incidence of hematoma enlargement in patients with ultra-acute ICH in this study was 15.0%, which was lower than that in other series in which blood pressure was not reduced aggressively. This finding suggests that aggressive SBP lowering to below 140 mmHg has a preventive effect on hematoma enlargement in patients with ultra-acute ICH. (author)

Association between gingivitis and anterior gingival enlargement in subjects undergoing fixed orthodontic treatment

Science.gov (United States)

Zanatta, Fabricio Batistin; Ardenghi, Thiago Machado; Antoniazzi, Raquel Pippi; Pinto, Tatiana Militz Perrone; Rösing, Cassiano Kuchenbecker

2014-01-01

Objective The aim of this study was to investigate the association among gingival enlargement (GE), periodontal conditions and socio-demographic characteristics in subjects undergoing fixed orthodontic treatment. Methods A sample of 330 patients undergoing fixed orthodontic treatment for at least 6 months were examined by a single calibrated examiner for plaque and gingival indexes, probing pocket depth, clinical attachment loss and gingival enlargement. Socio-economic background, orthodontic treatment duration and use of dental floss were assessed by oral interviews. Associations were assessed by means of unadjusted and adjusted Poisson's regression models. Results The presence of gingival bleeding (RR 1.01; 95% CI 1.00-1.01) and excess resin around brackets (RR 1.02; 95% CI 1.02-1.03) were associated with an increase in GE. No associations were found between socio-demographic characteristics and GE. Conclusion Proximal anterior gingival bleeding and excess resin around brackets are associated with higher levels of anterior gingival enlargement in subjects under orthodontic treatment. PMID:25162567

Proteomic Analysis of PEG-Fractionated UV-C Stress-Response Proteins in Globe Artichoke

NARCIS (Netherlands)

Falvo, S.; Acquadro, A.; Albo, A.G.; America, A.H.P.; Lanteri, S.

2012-01-01

Plants respond to UV stress by producing antioxidant molecules and by altering their metabolism through the regulation of specific gene family members. Globe artichoke (Cynara cardunculus var. scolymus L.-Compositae family) is an attractive model species for studying the protein networks involved in

GLOBE Observer and the Association of Science & Technology Centers: Leveraging Citizen Science and Partnerships for an International Science Experiment to Build Climate Literacy

Science.gov (United States)

Riebeek Kohl, H.; Chambers, L. H.; Murphy, T.

2016-12-01

For more that 20 years, the Global Learning and Observations to Benefit the Environment (GLOBE) Program has sought to increase environment literacy in students by involving them in the process of data collection and scientific research. In 2016, the program expanded to accept observations from citizen scientists of all ages through a relatively simple app. Called GLOBE Observer, the new program aims to help participants feel connected to a global community focused on advancing the scientific understanding of Earth system science while building climate literacy among participants and increasing valuable environmental data points to expand both student and scientific research. In October 2016, GLOBE Observer partnered with the Association of Science & Technology Centers (ASTC) in an international science experiment in which museums and patrons around the world collected cloud observations through GLOBE Observer to create a global cloud map in support of NASA satellite science. The experiment was an element of the International Science Center and Science Museum Day, an event planned in partnership with UNESCO and ASTC. Museums and science centers provided the climate context for the observations, while GLOBE Observer offered a uniform experience and a digital platform to build a connected global community. This talk will introduce GLOBE Observer and will present the results of the experiment, including evaluation feedback on gains in climate literacy through the event.

Detection of salmonella on globe fruits using pulse excited magnetoelastic biosensors

Science.gov (United States)

Wikle, Howard C.; Du, Songtao; Prorok, Barton C.; Chin, Bryan A.

2015-05-01

This paper describes the results of a research project to investigate magnetoelastic (ME) biosensors actuated with a pulse excitation to measure the concentration of Salmonella Typhimurium of globe fruits. The ME biosensors are based on an acoustic wave resonator platform that is a freestanding (free-free) thin ribbon of magnetostrictive material with a lengthto- width ratio of 5:1. A biorecognition probe coated on the surface of the resonator platform binds with a targeted pathogen, i.e. E2 phage that binds with S. Typhimurium. The biosensor was actuated to vibrate longitudinally such that the resonant frequency depended primarily on the length of sensor and its overall mass. A pulsed excitation and measurement system was used to actuate micron scale ME biosensors to vibrate. The biosensor responds in a ring-down manner, a damped decay of the resonance amplitude, from which the resonant frequency was measured. An increase in mass due to the binding of the target pathogen resulted in a decrease in the resonant frequency. The pulsed excitation and measurement system that was developed under this effort and the characterization of its performance on the measurement of Salmonella concentrations on globe fruits is described.

GlobeLand30 as an alternative fine-scale global land cover map

DEFF Research Database (Denmark)

Jokar Arsanjani, Jamal; Tayyebi, A.; Vaz, E.

2016-01-01

land cover information such as developing countries. In this study, we look at GlobeLand30 of 2010 for Iran in order to find out the accuracy of this dataset as well as its implications. By having looked at 6 selected study sites around larger cities representing dissimilar eco-regions covering rural...

The effect of low dose rocuronium on globe position, muscle relaxation and ventilation in dogs: a clinical study.

Science.gov (United States)

Auer, Ulrike; Mosing, Martina; Moens, Yves P S

2007-01-01

The purpose of this study was to evaluate globe position, muscle relaxation and changes in ventilatory parameters after intravenous administration of 0.1 mg/kg rocuronium. Prospective clinical study. Sixteen dogs of different breeds, with a body weight of 22.1 +/- 13 kg and age of 5.6 +/- 2.8 years (mean +/- SD), were anesthetized for a short ophthalmic examination requiring central position of the globe. All dogs were premedicated with 0.005 mg/kg medetomidine and 0.1 mg/kg methadone IV. Anesthesia was induced with propofol to effect and maintained with 10 mg/kg/h propofol by continuous rate infusion. Following endotracheal intubation all dogs breathed 100% oxygen via an anesthetic circle system. Neuromuscular function was assessed with an acceleromyograph (TOF-Guard, Organon Teknika NV, Turnhout, Belgium) and by stimulation of the nervus peroneus superficialis. The ventilation parameters were measured using spirometry and capnography. After baseline measurements 0.1 mg/kg rocuronium was administered IV. Minute volume (MV), tidal volume (Vt), respiratory rate (RR), end expiratory carbon dioxide concentration (PE'CO(2)) and maximal depression of the response of the first twitch (T1) of train-of-four (TOF) stimulation and train-of-four ratio (TOFR) was measured. The change in the position of the globe was recorded. T1 decreased to 61 +/- 18% and the TOF ratio to 45 +/- 21% of baseline values. Both parameters returned to baseline after 9 min. There was no significant reduction in MV, TV and RR and no increase in PE'CO(2). The globe rotated to a central position of 45 +/- 7.7 s after administration of rocuronium and remained there for 23 +/- 10.8 min in all dogs. Rocuronium administered intravenously at a dose of 0.1 mg/kg to dogs causes a central position of the globe but minimal impairment of ventilation parameters.

VISUALIZATION OF VGI DATA THROUGH THE NEW NASA WEB WORLD WIND VIRTUAL GLOBE

Directory of Open Access Journals (Sweden)

M. A. Brovelli

2016-06-01

Full Text Available GeoWeb 2.0, laying the foundations of Volunteered Geographic Information (VGI systems, has led to platforms where users can contribute to the geographic knowledge that is open to access. Moreover, as a result of the advancements in 3D visualization, virtual globes able to visualize geographic data even on browsers emerged. However the integration of VGI systems and virtual globes has not been fully realized. The study presented aims to visualize volunteered data in 3D, considering also the ease of use aspects for general public, using Free and Open Source Software (FOSS. The new Application Programming Interface (API of NASA, Web World Wind, written in JavaScript and based on Web Graphics Library (WebGL is cross-platform and cross-browser, so that the virtual globe created using this API can be accessible through any WebGL supported browser on different operating systems and devices, as a result not requiring any installation or configuration on the client-side, making the collected data more usable to users, which is not the case with the World Wind for Java as installation and configuration of the Java Virtual Machine (JVM is required. Furthermore, the data collected through various VGI platforms might be in different formats, stored in a traditional relational database or in a NoSQL database. The project developed aims to visualize and query data collected through Open Data Kit (ODK platform and a cross-platform application, where data is stored in a relational PostgreSQL and NoSQL CouchDB databases respectively.

Visualization of Vgi Data Through the New NASA Web World Wind Virtual Globe

Science.gov (United States)

Brovelli, M. A.; Kilsedar, C. E.; Zamboni, G.

2016-06-01

GeoWeb 2.0, laying the foundations of Volunteered Geographic Information (VGI) systems, has led to platforms where users can contribute to the geographic knowledge that is open to access. Moreover, as a result of the advancements in 3D visualization, virtual globes able to visualize geographic data even on browsers emerged. However the integration of VGI systems and virtual globes has not been fully realized. The study presented aims to visualize volunteered data in 3D, considering also the ease of use aspects for general public, using Free and Open Source Software (FOSS). The new Application Programming Interface (API) of NASA, Web World Wind, written in JavaScript and based on Web Graphics Library (WebGL) is cross-platform and cross-browser, so that the virtual globe created using this API can be accessible through any WebGL supported browser on different operating systems and devices, as a result not requiring any installation or configuration on the client-side, making the collected data more usable to users, which is not the case with the World Wind for Java as installation and configuration of the Java Virtual Machine (JVM) is required. Furthermore, the data collected through various VGI platforms might be in different formats, stored in a traditional relational database or in a NoSQL database. The project developed aims to visualize and query data collected through Open Data Kit (ODK) platform and a cross-platform application, where data is stored in a relational PostgreSQL and NoSQL CouchDB databases respectively.

Morphology and morphometry of the human sublingual glands in mouth floor enlargements of edentulous patients

Directory of Open Access Journals (Sweden)

Josiane Costa Rodrigues de SA

2013-12-01

Full Text Available Asymptomatic mouth floor enlargements may be observed in edentulous patients. These masses, which protrude from the mouth floor, may complicate the fitting of dentures and require surgery. Whether this "entity" may be considered an anatomical variation of the mouth floor or represent specific alterations in the sublingual gland is not known. Objective: The aim of this work is to investigate the morphological and morphometric aspects of the sublingual glands of edentulous patients with mouth floor enlargements and compare the glands of these patients with the sublingual glands of human cadavers. Material and Methods: Microscopic evaluation was performed on human sublingual glands from edentulous patients with mouth floor enlargements (n=20 and edentulous cadavers (n=20. The patients and cadavers were of similar ages. The data were compared using Mann-Whitney U, Fisher's exact and Student's t tests (p0.05. Only the variables "autolysis" and "congested blood vessels" presented statistical difference between groups (p=0.014; p=0.043. The morphometric study revealed that the volume densities of acini, ducts, stroma and adipose tissue were similar between the groups (p>0.05. CONCLUSION: The microscopic characteristics of the sublingual glands in mouth floor enlargements in edentulous patients correspond to characteristics associated with the normal aging process. The glands are not pathological and represent an age-related alteration that occurs with or without the presence of the mouth floor enlargements.

Enlargement of thalamic nuclei in Tourette syndrome

DEFF Research Database (Denmark)

Miller, Ann M; Bansal, Ravi; Hao, Xuejun

2010-01-01

CONTEXT: The basal ganglia and thalamus together connect in parallel closed-loop circuits with the cortex. Previous imaging studies have shown modifications of the basal ganglia and cortical targets in individuals with Tourette syndrome (TS), but less is known regarding the role of the thalamus......-subcortical circuits constitute an anatomical crossroad wherein enlargement of motor nuclei may represent activity-dependent hypertrophy within this component of cortical-subcortical motor circuits, or an adaptive response within a larger putative compensatory system that could thereby directly modulate activity...

Immunoglobulin G4-related dacyroadenitis presenting as bilateral chorioretinal folds from severely enlarged lacrimal glands

Directory of Open Access Journals (Sweden)

Toru Kurokawa

2018-03-01

Conclusions and importance: This is the first account of chorioretinal fold formation by severely enlarged lacrimal glands appearing in IgG4-related dacryoadenitis. Chorioretinal fold formation by an enlarged lacrimal gland occurring bilaterally may represent a basis for suspecting IgG4-related dacryoadenitis. Prompt treatment is recommended for patients presenting with very large lacrimal glands to avoid visual impairment.

Globe Artichoke Callus as an Alternative System for the Production of Dicaffeoylquinic Acids

NARCIS (Netherlands)

Moglia, A.; Menin, B.; Comino, C.; Lanteri, S.; Beekwilder, M.J.

2012-01-01

Globe artichoke leaves are highly rich in phenolic acids, in particular chlorogenic acid and dicaffeoylquinic acids. The latter are of particular interest since they can exert a stronger antioxidant activity, due to the presence of two adjacent hydroxyl groups on each of their phenolic rings. Plant

Emergent risk factors associated with eyeball loss and ambulatory vision loss after globe injuries.

Science.gov (United States)

Hyun Lee, Seung; Ahn, Jae Kyoun

2010-07-01

The objective of this study was to evaluate risk factors associated with eyeball loss and ambulatory vision loss on emergent examination of patients with ocular trauma. We reviewed the medical records of 1,875 patients hospitalized in a single tertiary referral center between January 2003 and December 2007. Emergent examinations included a history of trauma, elapsed time between injury and hospital arrival, visible intraocular tissues, and initial visual acuity (VA) using a penlight. The main outcome measures were ocular survival and ambulatory vision survival (>20/200) at 1 year after trauma using univariate and multivariate regression analysis. The ocular trauma scores were significantly higher in open globe injuries than in closed globe injuries (p eyeball loss. Elapsed time more than 12 hours and visible intraocular tissues were the significant risk factors associated with ambulatory vision loss. The most powerful predictor of eyeball loss and ambulatory vision loss was eyeball rupture. In closed globe injuries, there were no significant risk factors of eyeball loss, whereas initial vision less than LP and the presence of relative afferent pupillary defect were the significant risk factors associated with ambulatory vision loss. An initial VA less than LP using a penlight, a history of golf ball injury, and elapsed time more than 12 hours between ocular trauma and hospital arrival were associated with eyeball loss and ambulatory vision loss. Physicians should bear these factors in mind so that they can more effectively counsel patients with such injuries.

The New Report of Artichoke latent virus (ArLV) From Globe Artichoke in Turkey

OpenAIRE

ERKAN, Semih; GÜMÜŞ, Mustafa; DUMAN, İbrahim; PAYLAN, İsmail Can; ERGÜN, Müge

2014-01-01

n recent years, some of artichoke growers in Aegean region of Turkey stated that globe artichoke (Cynara cardunculus L. subsp. scolymus (L.) Hayek) plants in their fields have showed virus-like symptoms. So, in order to identify viruses

Low-cost airlines in Europe: Network structures after the enlargement of the European Union

Directory of Open Access Journals (Sweden)

Dudas Gabor

2010-01-01

Full Text Available The liberalization of the European air opened the strictly regulated European market, and contributed to the appearance and quick spread of the Low-Cost Carriers (LCCs. At the beginning of the 21st century the low cost traffic absolutely concentrated on the Western European market but after the enlargement of the European Union (EU LCCs started their operations in Eastern Europe enlarging and enriching the former evolved network structures. The aim of this paper is to trace the evolution of the route network as a result of EU expansion. During the study we came to the conclusion that in the time period after the EU enlargement the European LCC traffic showed dynamic development, route networks widened and the number of accessible destinations doubled. Comparing the LCCs network structures we defined three main characteristics, which represents the North-South flows, the West-East routes and the mixed network structure.

GLOBE at Night: a Worldwide Citizen-Science Program to Increase Awareness of Light Pollution by Measuring Night Sky Brightness

Science.gov (United States)

Walker, C. E.; Pompea, S. M.

2011-12-01

The emphasis in the international citizen-science, star-hunting campaign, GLOBE at Night, is in bringing awareness to the public on issues of light pollution. Light pollution threatens not only observatory sites and our "right to starlight", but can affect energy consumption, wildlife and health. GLOBE at Night has successfully reached a few 100,000 citizen-scientists. What has contributed to its success? Foundational resources are available to facilitate the public's participation in promoting dark skies awareness. The GLOBE at Night website explains clearly the simple-to-participate-in 5 step program and offers background information and interactive games on key concepts. To promote the campaign via popular social media, GLOBE at Night created Facebook and Twitter pages. The program has been expanded to include trainings of the general public, but especially educators in schools, museums and science centers, in unique ways. Education kits for dark skies awareness have been distributed at the training workshops. The kit includes material for a light shielding demonstration, a digital Sky Quality Meter and "Dark Skies Rangers" activities. The activities are on how unshielded light wastes energy, how light pollution affects wildlife and how one can participate in a citizen-science star-hunt like GLOBE at Night. To increase participation in the 2011 campaign, children and adults submitted their sky brightness measurements in real time with smart phones or tablets using the web application at www.globeatnight.org/webapp/. With smart phones and tablets, the location, date and time register automatically. For those without smart mobile devices, user-friendly tools on the GLOBE at Night report page were reconfigured to determine latitude and longitude more easily and accurately. As a proto-type for taking multiple measurements, people in Tucson found it easy to adopt a street and take measurements every mile for the length of the street. The grid of measurements

Intestinal

International Nuclear Information System (INIS)

Cardenas, Rene; Haro, Elfa

2002-01-01

The paper present the diagnosic sensitivit of gastro esophagic scintigraphy (GCE) in children with suspiction of gastro esophagic reflux (RGE), as well as to evidence bronchial aspiratin in cases with suspected RGE. There was studied two groups of children: group A: Include 73 childs with documented diagnosis of RGE, by meas of cine esophagography. Group B: Include 22 children with symptoms of suspiction of. (The author)

Writing education around the globe: introduction and call for a new global analysis

NARCIS (Netherlands)

Graham, S.; Rijlaarsdam, G.

This paper presents a special issue on writing around the globe. Researchers from across the world describe writing practices in their country using a wide variety of methodology. The paper show that while there are many similarities in writing instruction from one country to the next, there are

New predictor of aortic enlargement in uncomplicated type B aortic dissection based on elliptic Fourier analysis.

Science.gov (United States)

Sato, Hiroshi; Ito, Toshiro; Kuroda, Yosuke; Uchiyama, Hiroki; Watanabe, Toshitaka; Yasuda, Naomi; Nakazawa, Junji; Harada, Ryo; Kawaharada, Nobuyoshi

2017-12-01

This study aimed to re-examine the conventional predictive factors for dissected aortic enlargement, such as the aortic and false lumen diameter and to consider whether the morphological elements of the dissected aorta could be predictors by quantifying the 'shape' of the true lumen based on elliptic Fourier analysis. A total of 80 patients with uncomplicated type B aortic dissection were included. The patients were divided into 'Enlargement group' and 'No Change group.' Between the 2 groups, the mean systolic blood pressure during follow-up, aortic and false lumen maximum diameters, and analysed morphological data were compared using each statistical method. The maximum aortic and false lumen diameters were significantly larger in the Enlargement group than in the No Change group (39.3 vs 35.9 mm; P = 0.0058) (23.5 vs 18.2 mm; P = 0.000095). The principal component 1, which is the data calculated by elliptic Fourier analysis, was significantly lower in the Enlargement group than in the No Change group (0.020 vs - 0.072; P = 0.000049). The mean systolic blood pressure ≥130 mmHg, aortic diameter, false lumen diameter and principal component 1 were included in the Cox proportional hazard model as covariates to determine the significant predictive variable. Principal component 1 demonstrated the only significance with aortic enlargement on multivariate analysis (odds ratio = 0.32; P = 0.048). The analysed and calculated morphological data of the shape of the true lumen can be more effective predictive factors of aortic enlargement of type B dissection than the conventional factors. © The Author 2017. Published by Oxford University Press on behalf of the European Association for Cardio-Thoracic Surgery. All rights reserved.

Isolation and mapping of a C3'H gene (CYP98A49) from globe artichoke, and its expression upon UV-C stress

NARCIS (Netherlands)

Moglia, A.; Comino, C.; Portis, E.; Acquadro, A.; Vos, de C.H.; Beekwilder, M.J.; Lanteri, S.

2009-01-01

Globe artichoke represents a natural source of phenolic compounds with dicaffeoylquinic acids along with their biosynthetic precursor chlorogenic acid (5-caffeoylquinic acid) as the predominant molecules. We report the isolation and characterization of a full-length cDNA and promoter of a globe

CT appearance of hilar and mediastinal enlarged lymph nodes of coal worker's pneumoconiosis

International Nuclear Information System (INIS)

Ma Daqing; Guan Yansheng; Tang Hongqu; He Wen; Chen Budong; Zhang Yansong; Li Jun

2000-01-01

Objective: To study the CT appearance of the hilar and mediastinal enlarged lymph nodes in coal worker's pneumoconiosis (CWP), its pathological basis and diagnostic value for CWR complicated with lung cancer. Methods: (1) Twelve isolated lungs with CWP obtained at autopsy were inflated and fixed. CT scan was performed. The pathologic findings of enlarged lymph nodes were identified. (2) CT findings of hilar and mediastinal enlarged lymph nodes of 71 cases with CWP and 22 cases of CWP complicated with lung cancer were analyzed. Results: (1) Most of the enlarged hilar and mediastinal lymph nodes in simple CWR was in third stage of fibrosis. The fourth stage of fibrosis was only seen in lymph nodes of a case with complicated CWP. In this case the necrotic materials of lymph nodes eroded adjacent bronchi and vessels, and coalesced with progressive massive fibrosis (PMF). (2) The average number of lymph nodes in cases of complicated CWP was more than that of simple CWP (P 2 cm was 7.4%. (3) The prevalence of lymph nodes calcification in CWP was 61.1%, but egg shell calcification was only 14.7%. (4) In the cases of CWP complicated with lung cancer, lymph node > 2 cm was 20.8%, that was more than CWP (P 3 cm was 7.6%. Conclusion: Lymph nodes up to 1 cm may have dust fibrosis and coal silicosis nodules. The lymph nodes >2 cm is more common in CWP complicated with lung cancer than in simple CWP. The lymph nodes > 3 cm indicates higher probability of CWP with lung cancer than PMF

A study on the force balance of an unbalanced globe valve

International Nuclear Information System (INIS)

Yang, Sang Min; Cho, Taik Dong; Ko, Sung Ho; Lee, Ho Young

2007-01-01

A pneumatic control valve is a piping element that controls the volumetric flow rate and pressure of a fluid: it is necessary to analyze the characteristics of the forces with respect to the opening of the valve in order to evaluate its operating performance. The forces occurring during operation are: resisting force and actuator force, where the load resistance is mostly affected by the fluid pressure difference of the valve. In this study, a force balance equation derived from the equilibrium relationship between the resisting force and the actuator force of an unbalanced globe valve is proposed, and the force balance equations are used to model the dynamic equations of a pneumatic unbalanced globe valve installed in nuclear power plants. A CFD analysis is also carried out to evaluate the pressure distribution and forces acting on the top and bottom planes of the valve plug. The results of this analysis have been verified through experimentation. This study has shown that the fluid pressure difference between the inlet and outlet of the valve, measured from the force balance equation of an unbalanced valve, should actually be examined with the fluid-pressure difference between the top and bottom side of the valve plug

Mitigating Mosquito Disease Vectors with Citizen Science: a Review of the GLOBE Observer Mosquito Habitat Mapper Pilot and Implications for Wide-scale Implementation

Science.gov (United States)

Riebeek Kohl, H.; Low, R.; Boger, R. A.; Schwerin, T. G.; Janney, D. W.

2017-12-01

The spread of disease vectors, including mosquitoes, is an increasingly significant global environmental issue driven by a warming climate. In 2017, the GLOBE Observer Program launched a new citizen science initiative to map mosquito habitats using the free GLOBE Observer App for smart phones and tablets. The app guides people to identify mosquito larvae and breeding sites, and then once documented, to eliminate or treat the site to prevent further breeding. It also gives citizen scientists the option to identify the mosquito larvae species to determine whether it is one of three genera that potentially could transmit Zika, dengue fever, yellow fever, chikungunya, and other diseases. This data is uploaded to an international database that is freely available to the public and science community. GLOBE Observer piloted the initiative with educators in the United States, Brazil, and Peru, and it is now open for global participation. This presentation will discuss lessons learned in the pilot phase as well as plans to implement the initiative worldwide in partnership with science museums and science centers. GLOBE Observer is the non-student citizen science arm of the Global Learning and Observations to Benefit the Environment (GLOBE) Program, a long-standing, international science and education program that provides students and citizen scientists with the opportunity to participate in data collection and the scientific process, and contribute meaningfully to our understanding of the Earth system and global environment. GLOBE Observer data collection also includes cloud cover and cloud type and land cover/land use (in late 2017).

The eastward enlargement of the eurozone: social and policy aspects in Portugal, Spain and Italy

OpenAIRE

Galego, Aurora; Caétano, José; Costa, Sofia; Liiv, Reilika

2003-01-01

This report explores some features of the social dimension of enlargement regarding the Southern EU-Member countries, namely Portugal, Spain and Italy. Economic theory suggests that integration may affect wages, employment and income distribution through changes on trade, FDI and migration flows. By removing all barriers to the free movement of goods and services, capital and labour, Eastward Enlargement will affect the location of economic activities, innovation, and technology. Subsequently...

Technical Challenges and Lessons from the Migration of the GLOBE Data and Information System to Utilize Cloud Computing Service

Science.gov (United States)

Moses, J. F.; Memarsadeghi, N.; Overoye, D.; Littlefield, B.

2016-12-01

The Global Learning and Observation to Benefit the Environment (GLOBE) Data and Information System supports an international science and education program with capabilities to accept local environment observations, archive, display and visualize them along with global satellite observations. Since its inception twenty years ago, the Web and database system has been upgraded periodically to accommodate the changes in technology and the steady growth of GLOBE's education community and collection of observations. Recently, near the end-of-life of the system hardware, new commercial computer platform options were explored and a decision made to utilize Cloud services. Now the GLOBE DIS has been fully deployed and maintained using Amazon Cloud services for over two years now. This paper reviews the early risks, actual challenges, and some unexpected findings as a result of the GLOBE DIS migration. We describe the plans, cost drivers and estimates, highlight adjustments that were made and suggest improvements. We present the trade studies for provisioning, for load balancing, networks, processing , storage, as well as production, staging and backup systems. We outline the migration team's skills and required level of effort for transition, and resulting changes in the overall maintenance and operations activities. Examples include incremental adjustments to processing capacity and frequency of backups, and efforts previously expended on hardware maintenance that were refocused onto application-specific enhancements.

Technical Challenges and Lessons from the Migration of the GLOBE Data and Information System to Utilize Cloud Computing Service

Science.gov (United States)

Moses, John F.; Memarsadeghi, Nargess; Overoye, David; Littlefield, Brain

2017-01-01

The Global Learning and Observation to Benefit the Environment (GLOBE) Data and Information System supports an international science and education program with capabilities to accept local environment observations, archive, display and visualize them along with global satellite observations. Since its inception twenty years ago, the Web and database system has been upgraded periodically to accommodate the changes in technology and the steady growth of GLOBEs education community and collection of observations. Recently, near the end-of-life of the system hardware, new commercial computer platform options were explored and a decision made to utilize Cloud services. Now the GLOBE DIS has been fully deployed and maintained using Amazon Cloud services for over two years now. This paper reviews the early risks, actual challenges, and some unexpected findings as a result of the GLOBE DIS migration. We describe the plans, cost drivers and estimates, highlight adjustments that were made and suggest improvements. We present the trade studies for provisioning, for load balancing, networks, processing, storage, as well as production, staging and backup systems. We outline the migration teams skills and required level of effort for transition, and resulting changes in the overall maintenance and operations activities. Examples include incremental adjustments to processing capacity and frequency of backups, and efforts previously expended on hardware maintenance that were refocused onto application-specific enhancements.

CineGlobe Film Festival, Wednesday programme with Science Story Telling Hackathon and Oculus Rift

CERN Multimedia

Marcelloni De Oliveira, Claudia

2015-01-01

Besides the short-film competitions, the second day of 2015 CineGlobe included a Soirée Oculus Rift with the public launch of the “Storytelling Science” Hackathon. CineGlobe and Festival Tous Ecrans joined forces to launch the “Storytelling Science” hackathon, in collaboration with Tribeca Film Institute and LIFT Conference. The keynote speech was given by renowned filmmaker and transmedia creator Michel Reihlac, who spoke about the role of interactive and immersive storytelling techniques in cinematic narrative. By placing the viewer in the center of the story, these new technologies are profoundly changing the way we tell stories. Michel Reilhac designs innovative story based experiences, using digital platforms (cinema, tv, mobile, tablets, …) and real life events. His creative approach to storytelling ambitions to offer viewers/ participants a unique opportunity for an immersive, participatory and interactive experience. During the evening, Oculus Rift virtual reality headsets were available to...

Spaceflight-Induced Visual Impairment and Globe Deformations in Astronauts Are Linked to Orbital Cerebrospinal Fluid Volume Increase.

Science.gov (United States)

Alperin, Noam; Bagci, Ahmet M

2018-01-01

Most of the astronauts onboard the International Space Station (ISS) develop visual impairment and ocular structural changes that are not fully reversible upon return to earth. Current understanding assumes that the so-called visual impairments/intracranial pressure (VIIP) syndrome is caused by cephalad vascular fluid shift. This study assesses the roles of cerebrospinal fluid (CSF) and intracranial pressure (ICP) in VIIP. Seventeen astronauts, 9 who flew a short-duration mission on the space shuttle (14.1 days [SD 1.6]) and 7 who flew a long-duration mission on the ISS (188 days [SD 22]) underwent MRI of the brain and orbits to assess the pre-to-post spaceflight changes in four categories: VIIP severity measures: globe flattening and nerve protrusion; orbital and ventricular CSF volumes; cortical gray and white matter volumes; and MR-derived ICP (MRICP). Significant pre-to-post-flight increase in globe flattening and optic nerve protrusion occurred only in the long-duration cohort (0.031 [SD 0.019] vs -0.001 [SD 0.006], and 0.025 [SD 0.013] vs 0.001 [SD 0.006]; p < 0.00002 respectively). The increased globe deformations were associated with significant increases in orbital and ventricular CSF volumes, but not with increased tissue vascular fluid content. Additionally, a moderate increase in MRICP of 6 mmHg was observed in only two ISS astronauts with large ocular structure changes. These findings are evidence for the primary role of CSF and a lesser role for intracranial cephalad fluid-shift in the formation of VIIP. VIIP is caused by a prolonged increase in orbital CSF spaces that compress the globes' posterior pole, even without a large increase in ICP.

Orbital T-Cell Lymphoma with Discrete Enlargements of All Extraocular Muscles Bilaterally in Patient with Moon Face Countenance

Directory of Open Access Journals (Sweden)

Hideaki Kawakami

2017-01-01

Full Text Available Purpose. To report our findings in a case of orbital T-cell lymphoma in which all of the extraocular muscles (EOMs were bilaterally and discretely enlarged and the patient had a moon face countenance. Case. A 59-year-old woman presented with visual disturbances in her left eye, hyperemia in both eyes, and a moon face countenance. Examinations showed limited upward gaze in the right eye, blepharoptosis, hypertropia, and limited downward and rightward gaze in the left eye. Slit-lamp examination showed only chemosis and hyperemia of both eyes. Magnetic resonance imaging with contrast revealed discrete enlargements of the muscle bellies in all EOMs without abnormalities of the orbital fat in both eyes. Blood examinations excluded thyroid- and IgG4-related ophthalmopathy, and EOM biopsy revealed peripheral T-cell lymphoma. After beginning aggressive chemotherapy, the enlarged EOMs, limited eye motility, and moon face countenance improved. Unfortunately, the patient died of sepsis during the chemotherapy. Conclusions. A lymphoma should be included in the differential diagnosis of eyes with enlarged EOMs. Because lymphomas can lead to death, it is important for clinicians to consider lymphomas in eyes with enlarged EOMs.

Public outreach: les spectacles du Globe

CERN Document Server

2006-01-01

Shows at the Globe of Science and Innovation in connection with the exhibition «A des années-lumière» Wednesday 8 November 2006, 2.30 p.m. (in French): 'Cooking with the stars' Professor BEUZ and his assistant Mr POZZONI, a clown double-act, will introduce children to the cosmos, the formation of the universe and the creation of stars and the solar system. On the menu: eggs, biscuits, a 'comet' sausage, giant onions, noodles, 'primordial' soup, instant pudding, fruit and vegetables. A spicy and scholarly recipe that will satisfy little gourmets and budding astronomers alike. This event is a version of the comedy 'How to make the Universe' specially adapted for children. For young children (7 years and upwards) Free admittance, by reservation only: + 41(0)22 767 76 76 Thursday 9 and Friday 10 November 2006, 8.00 p.m. (in French): 'How to make the Universe' At the end of a meal, Professor BEUZ and his assistant Mr POZZONI tell us the story of how the universe was formed, from the Big Bang to the arriv...

Around the Globe with Buzz Aldrin

CERN Multimedia

Katarina Anthony

2011-01-01

Buzz Aldrin! The news caused a sensation: his arrival was imminent. The man who, 40 years ago, first step foot on the moon, was to do the same at CERN.   Buzz Aldrin dumps the pilot beams from the LHC. Visiting the Globe on 1 March to endorse General Motors’ (GM) new ecological programme, Buzz Aldrin took advantage of the occasion to take a whistle-stop tour of the Organisation. “CERN is dealing with things going very fast underground; I’m dealing with things going fast – not that fast though! – up in orbit,” he said. Accompanied by his wife Lois and singer Katie Melua - also invited by GM to perform at the private event - Buzz began his visit with a short introduction to CERN at the Universe of Particles exhibit. He then met with Andrzej Siemko, group leader of the LHC machine protection, at the SM-18 super conducting magnet test facility. The astronaut’s last stop was at the CCC, where the LHC team had somethi...

Globe : Fête de la science 2007

CERN Multimedia

2007-01-01

FROM 8 TO 13 OCTOBER 2007 Globe of Science and Innovation - Route de Meyrin, 1211 Geneva >>> "Expo NANO. Technology takes on a new dimension". Open on the Monday, Tuesday, Thursday and Friday from 2.00 p.m. to 5.30 p.m. and on the Wednesday and Saturday from 10.00 a.m. to 5.30 p.m. >>> Conference/Debate on the LHC "The LHC: an accelerator of science". Thursday 11 October from 8.00 p.m. to 10 p.m. CERN will soon commission the world’s most powerful accelerator, the LHC. This machine, the latest and greatest in a long line of CERN accelerators, is designed to provide answers to the remaining unsolved mysteries surrounding the building blocks of matter. Speakers : Jean-Philippe Tock, Jean-Pierre Revol, Daniel Denegri, Richard Jacobsson and Laurent Chevalier Free entrance. Please book by calling + 41 (0)22 767 76 76 >>> "Poussière d’étoiles" workshop: Saturday 13 October from 10 a.m. to 5.30 p.m. The "Poussière d’étoiles...

Income, Deprivation and Economic Stress in the Enlarged European Union

Science.gov (United States)

Whelan, Christopher T.; Maitre, Bertrand

2007-01-01

At risk of poverty indicators based on relative income measures suggest that within the enlarged EU societies located at quite different points on a continuum of affluence have similar levels of poverty. Substantial differences in levels of income between societies do not in themselves invalidate this approach. However, the relative income…

The Costa Rica GLOBE (Global Learning and Observations to Benefit the Environment) Project as a Learning Science Environment

Science.gov (United States)

Castro Rojas, María Dolores; Zuñiga, Ana Lourdes Acuña; Ugalde, Emmanuel Fonseca

2015-12-01

GLOBE is a global educational program for elementary and high school levels, and its main purpose in Costa Rica is to develop scientific thinking and interest for science in high school students through hydrology research projects that allow them to relate science with environmental issues in their communities. Youth between 12 and 17 years old from public schools participate in science clubs outside of their regular school schedule. A comparison study was performed between different groups, in order to assess GLOBE's applicability as a learning science atmosphere and the motivation and interest it generates in students toward science. Internationally applied scales were used as tools for measuring such indicators, adapted to the Costa Rican context. The results provide evidence statistically significant that the students perceive the GLOBE atmosphere as an enriched environment for science learning in comparison with the traditional science class. Moreover, students feel more confident, motivated and interested in science than their peers who do not participate in the project. However, the results were not statistically significant in this last respect.

IDP camp evolvement analysis in Darfur using VHSR optical satellite image time series and scientific visualization on virtual globes

Science.gov (United States)

Tiede, Dirk; Lang, Stefan

2010-11-01

In this paper we focus on the application of transferable, object-based image analysis algorithms for dwelling extraction in a camp for internally displaced people (IDP) in Darfur, Sudan along with innovative means for scientific visualisation of the results. Three very high spatial resolution satellite images (QuickBird: 2002, 2004, 2008) were used for: (1) extracting different types of dwellings and (2) calculating and visualizing added-value products such as dwelling density and camp structure. The results were visualized on virtual globes (Google Earth and ArcGIS Explorer) revealing the analysis results (analytical 3D views,) transformed into the third dimension (z-value). Data formats depend on virtual globe software including KML/KMZ (keyhole mark-up language) and ESRI 3D shapefiles streamed as ArcGIS Server-based globe service. In addition, means for improving overall performance of automated dwelling structures using grid computing techniques are discussed using examples from a similar study.

Rauvolfia grandiflora (Apocynaceae extract interferes with staphylococcal density, enterotoxin production and antimicrobial activity

Directory of Open Access Journals (Sweden)

Lanamar de Almeida Carlos

2010-10-01

Full Text Available Staphylococci bacteria are involved in many human and animal infections and development of alternative antimicrobial drugs against pathogenic bacteria is of great interest to the pharmaceutical industry. This study investigated the in vitro effect of Rauvolfia grandiflora methanol extract (root bark fraction (RGE on the density of ATCC strains of Staphylococcus aureus and Staphylococcus epidermidis, and a clinical enterotoxin-producer, S. aureus bovine strain. The alkaloid, isoreserpiline, obtained from dichloromethane extract of R. grandiflora was ineffective against the strains tested. After incubation of staphylococci strains in the presence of 1.2 mg.mL-1 RGE, a significant inhibition of cell growth was observed using both spectrophotometry and ELISA assays. Twelve drugs were evaluated for their antimicrobial effects on culture RGE-treated cells using the disk diffusion method. Penicillin resistant strains became sensitive to the drug after RGE treatment. Furthermore, enterotoxin production by RGE-treated S. aureus was evaluated using a standardized ELISA method. Although staphylococcal LSA 88 bovine strain cells remained viable after exposure to the extract, enterotoxin production was precluded in 20% after RGE treatment. Significant interference in staphylococci cell density, drug sensitivity and enterotoxin secretion was observed after treatment. The study highlights the necessity to find new methods of disease prevention and new antibiotic therapies against staphylococcal infections.

Rauvolfia grandiflora (apocynaceae) extract interferes with staphylococcal density, enterotoxin production and antimicrobial activity.

Science.gov (United States)

de Almeida Carlos, Lanamar; da Silva Amaral, Kenas Aguiar; Curcino Vieira, Ivo José; Mathias, Leda; Braz-Filho, Raimundo; Silva Samarão, Solange; Vieira-da-Motta, Olney

2010-07-01

Staphylococci bacteria are involved in many human and animal infections and development of alternative antimicrobial drugs against pathogenic bacteria is of great interest to the pharmaceutical industry. This study investigated the in vitro effect of Rauvolfia grandiflora methanol extract (root bark fraction) (RGE) on the density of ATCC strains of Staphylococcus aureus and Staphylococcus epidermidis, and a clinical enterotoxin-producer, S. aureus bovine strain. The alkaloid, isoreserpiline, obtained from dichloromethane extract of R. grandiflora was ineffective against the strains tested. After incubation of staphylococci strains in the presence of 1.2 μg.mL(-1) RGE, a significant inhibition of cell growth was observed using both spectrophotometry and ELISA assays. Twelve drugs were evaluated for their antimicrobial effects on culture RGE-treated cells using the disk diffusion method. Penicillin resistant strains became sensitive to the drug after RGE treatment. Furthermore, enterotoxin production by RGE-treated S. aureus was evaluated using a standardized ELISA method. Although staphylococcal LSA 88 bovine strain cells remained viable after exposure to the extract, enterotoxin production was precluded in 20% after RGE treatment. Significant interference in staphylococci cell density, drug sensitivity and enterotoxin secretion was observed after treatment. The study highlights the necessity to find new methods of disease prevention and new antibiotic therapies against staphylococcal infections.

INDIUM AND ZINC MEDIATED ONE-ATOM CARBOCYCLE ENLARGEMENT IN WATER. (R822668)

Science.gov (United States)

AbstractSix-, seven-, eight-membered rings are enlarged by one carbon-atom into seven-, eight- and nine-membered ring derivatives respectively, via indium or zinc mediated reactions in aqueous medium.

Hamlet's "Globe" and the Self as Performer in England and Japan

OpenAIRE

Shibuya, Yu

2004-01-01

In his paper, "Hamlet's 'Globe' and the Self as Performer in England and Japan," Yu Shibuya argues that Hamlet sees his life as a performance. Shibuya presents examples from Tsuneari Fukuda's Japanese translation to suggest that Fukuda makes choices that emphasize the theatrical side of Hamlet's character. If Hamlet perceives himself as an actor, then his definition of theater or an actor is ultimately a definition of himself. Shibuya uses the theme of self-definition to examine Kenneth Brana...

Minerals profile of two globe artichoke cultivars as affected by NPK fertilizer regimes.

Science.gov (United States)

Lombardo, Sara; Pandino, Gaetano; Mauromicale, Giovanni

2017-10-01

Globe artichoke is a proven source of various minerals (such as K, Fe and Zn) in the Mediterranean diet, but their content in response to fertilizer regime has not yet been investigated sufficiently. Thus, we monitored the effect of two contrasting nitrogen/phosphorus/potassium (NPK) fertilizer regimes (one balanced and the other excessive) on the minerals accumulation of 'Apollo' and 'Tema 2000' cultivars, grown in three Sicilian locations ('Landolina', 'Iannarello' and 'Zotto') - South Italy. Except for total nitrogen, the balanced fertilizer regime favoured the accumulation of both macro- and micro-minerals, but with a different extent depending especially on trial location. Particularly, plants grown at 'Iannarello' responded more strongly to the fertilizer regime with respect to K, P, Ca, Fe and Zn accumulation, as a result of its different soil characteristics than the other locations. Providing a balanced supply of nitrogen/phosphorus/potassium via fertilization can enhance the nutritive value of globe artichoke, but taking into account especially soil characteristics. Copyright © 2017 Elsevier Ltd. All rights reserved.

Globe Event | Lecture by Hervé Dessimoz and Thomas Büchi | 14 May

CERN Document Server

Globe Info

2013-01-01

At the summit of Sustainable Development, by Hervé Dessimoz and Thomas Büchi.   Globe de la science et de l'innovation Route de Meyrin, 1211 Genève Tuesday 14 May 2013 at 8:30 p.m. The lecture will be in French Refuge du Goûter. Hervé Dessimoz and Thomas Büchi have been committed to sustainable development since the 2000s. They created the Palais de l’Équilibre at Expo.02. They designed an exhibition in conjunction with the Cité de la Science et de l’Industrie (Paris) to educate visitors about sustainable development. The pavilion was donated to CERN by the Swiss Confederation and rebuilt on the CERN site in 2004. It is now known as the Globe of Science and Innovation. The Refuge du Goûter, on the slopes of Mont Blanc, is the culmination of their research into sustainable development, with the aim of demonstrating that if we can construct a building at 3835 m which is a...

Compositional Approach to Designing Fcc High-Entropy Alloys that Have an Enlarged Equiaxed Zone

Directory of Open Access Journals (Sweden)

Minju Kang

2018-01-01

Full Text Available A compositional approach to designing alloys that have an enlarged equiaxed zone is suggested in this study. The partitioning of elements during the solidification of CoCrFeMnNi high-entropy alloy (HEA was confirmed through a directional solidification quenching experiment. Several HEAs were designed to maximize the effects of constitutional and thermal undercooling by considering factors including solute enrichment at the columnar front and the melting temperatures and thermal conductivities of the individual elements. The newly designed HEAs were shown to have successfully enlarged equiaxed zones, and improved anisotropic properties.

GIS-project: geodynamic globe for global monitoring of geological processes

Science.gov (United States)

Ryakhovsky, V.; Rundquist, D.; Gatinsky, Yu.; Chesalova, E.

2003-04-01

A multilayer geodynamic globe at the scale 1:10,000,000 was created at the end of the nineties in the GIS Center of the Vernadsky Museum. A special soft-and-hardware complex was elaborated for its visualization with a set of multitarget object directed databases. The globe includes separate thematic covers represented by digital sets of spatial geological, geochemical, and geophysical information (maps, schemes, profiles, stratigraphic columns, arranged databases etc.). At present the largest databases included in the globe program are connected with petrochemical and isotopic data on magmatic rocks of the World Ocean and with the large and supperlarge mineral deposits. Software by the Environmental Scientific Research Institute (ESRI), USA as well as ArcScan vectrorizator were used for covers digitizing and database adaptation (ARC/INFO 7.0, 8.0). All layers of the geoinformational project were obtained by scanning of separate objects and their transfer to the real geographic co-ordinates of an equiintermediate conic projection. Then the covers were projected on plane degree-system geographic co-ordinates. Some attributive databases were formed for each thematic layer, and in the last stage all covers were combined into the single information system. Separate digital covers represent mathematical descriptions of geological objects and relations between them, such as Earth's altimetry, active fault systems, seismicity etc. Some grounds of the cartographic generalization were taken into consideration in time of covers compilation with projection and co-ordinate systems precisely answered a given scale. The globe allows us to carry out in the interactive regime the formation of coordinated with each other object-oriented databases and thematic covers directly connected with them. They can be spread for all the Earth and the near-Earth space, and for the most well known parts of divergent and convergent boundaries of the lithosphere plates. Such covers and time series

Significant Risk Factors for Postoperative Enlargement of Basal Ganglia Hematoma after Frameless Stereotactic Aspiration: Antiplatelet Medication and Concomitant IVH.

Science.gov (United States)

Son, Wonsoo; Park, Jaechan

2017-09-01

Frameless stereotactic aspiration of a hematoma can be the one of the treatment options for spontaneous intracerebral hemorrhage in the basal ganglia. Postoperative hematoma enlargement, however, can be a serious complication of intracranial surgery that frequently results in severe neurological deficit and even death. Therefore, it is important to identify the risk factors of postoperative hematoma growth. During a 13-year period, 101 patients underwent minimally invasive frameless stereotactic aspiration for basal ganglia hematoma. Patients were classified into two groups according to whether or not they had postoperative hematoma enlargement in a computed tomography scan. Baseline demographic data and several risk factors, such as hypertension, preoperative hematoma growth, antiplatelet medication, presence of concomitant intraventricular hemorrhage (IVH), were analysed via a univariate statistical study. Nine of 101 patients (8.9%) showed hematoma enlargement after frameless stereotactic aspiration. Among the various risk factors, concomitant IVH and antiplatelet medication were found to be significantly associated with postoperative enlargement of hematomas. In conclusion, our study revealed that aspirin use and concomitant IVH are factors associated with hematoma enlargement subsequent to frameless stereotactic aspiration for basal ganglia hematoma.

Effects of Q-switched and long-pulsed 1064 nm Nd:YAG laser on enlarged facial pores.

Science.gov (United States)

Lee, Chang Nam; Kim, You Jeong; Lee, Hyun Seung; Kim, Hei Sung

2009-12-01

'Enlarged facial pore' is a subjective term, which is not clearly defined but often complained by many. A diverse range of treatments are used though evidence of efficacy remains largely anecdotal. We report a series of nine patients who underwent a split face trial with Q-switched 1064 nm Nd:YAG and long-pulsed 1064 nm Nd:YAG laser to treat enlarged facial pores.

Micro-CT analyses of apical enlargement and molar root canal complexity

DEFF Research Database (Denmark)

Markvart, Merete; Darvann, Tron Andre; Larsen, Per

2012-01-01

AIM: To compare the effectiveness of two rotary hybrid instrumentation techniques with focus on apical enlargement in molar teeth and to quantify and visualize spatial details of instrumentation efficacy in root canals of different complexity. METHODOLOGY: Maxillary and mandibular molar teeth wer...

Effects of rocuronium bromide on globe position and respiratory function in isoflurane-anesthetized dogs: a comparison between three different dosages.

Science.gov (United States)

Briganti, Angela; Barsotti, Giovanni; Portela, Diego A; Di Nieri, Camilla; Breghi, Gloria

2015-03-01

To evaluate the effect on globe position and respiration of three dosages of intravenous rocuronium in isoflurane-anesthetized dogs. Thirty-two dogs anesthetized for ophthalmic procedures. The dogs were divided into four groups, each of eight animals (G1-G4). G1, G2, G3 received 0.075, 0.05, 0.03 mg/kg of IV rocuronium, respectively; G4 received 0.9% NaCl IV; all the treatments were administered when an end-tidal isoflurane of 1.1-1.2% was reached. Anesthesia was obtained with dexmedetomidine (2.5 mcg/kg IV), methadone (0.1 mg/kg IV), propofol (2 mg/kg IV), and isoflurane in oxygen. Neuromuscular function was assessed with acceleromyography by stimulation of the peroneal nerve using the train-of-four (ToF) and the ToF ratio (ToFR). Monitoring of cardiovascular and respiratory functions was performed. Changes in globe position were recorded. All three dosages of rocuronium produced centralization of the globe. Duration was 24.3 ± 4.2, 23.4 ± 3.6, and 8.7 ± 2.8 min, for G1, G2, and G3, respectively. The control group did not show globe centralization. No significant differences were found among the four groups in cardiovascular and respiratory parameters. Minute volume and ToFR were significantly lower in G1 compared with baseline values. All doses of rocuronium resulted in globe centralization. The higher dose provoked a transient respiratory depression and some degree of skeletal muscular blockade detectable with ToFR. No alterations in respiratory activity were present when 0.05 mg/kg was used. The 0.03 mg/kg dosage could be useful for very short ophthalmic procedures. © 2013 American College of Veterinary Ophthalmologists.

Communities, Boundaries and New Neighbours: the Discursive Construction of EU Enlargement

Directory of Open Access Journals (Sweden)

Giuditta Caliendo

2008-12-01

Full Text Available The institutional discourse of the European Union (EU is undergoing important changes that are also reflected by new initiatives in its communication policy. Against a background of widespread scepticism towards EU enlargement among the public, this change is driven by the need to promote the widening of its borders in a more effective way in order to prompt popular endorsement. Through the use of its textual and visual communicative strategies, the EU is thus finding new ways to buttress its legitimacy and raise consensus around its political actions. The node of interaction between citizens and institutions is represented by the informative publications of the EU (also made available on the europa website, which become a constitutive element in building Union-to-citizen communication. The analysis of textual and visual formulations of the European Commission’s key booklets on EU enlargement in the period from 2004 to 2007 - in terms of their content and pragmatic aims - reveals the emergence of new consensus-building strategies. Results show that a sense of allegiance and belonging attributed to a deepening of European integration is now increasingly linked to the practical advantages of EU enlargement, as expressed through the use of ‘promotional’ and strategic discursive practices. Moving away from a merely informative content, communication modes ‘migrate’ towards a more direct and ‘commodified’ type of message, while an increase in visual elements plays a complementing role in promoting legitimacy and a feeling of mutual belonging between ‘old’ and ‘new’ members of the European family.

Hot water-extracted Lycium barbarum and Rehmannia glutinosa inhibit proliferation and induce apoptosis of hepatocellular carcinoma cells

Science.gov (United States)

Chao, Jane C-J; Chiang, Shih-Wen; Wang, Ching-Chiung; Tsai, Ya-Hui; Wu, Ming-Shun

2006-01-01

AIM: To investigate the effect of hot water-extracted Lycium barbarum (LBE) and Rehmannia glutinosa (RGE) on cell proliferation and apoptosis in rat and/or human hepatocellular carcinoma (HCC) cells. METHODS: Rat (H-4-II-E) and human HCC (HA22T/VGH) cell lines were incubated with various concentrations (0-10 g/L) of hot water-extracted LBE and RGE. After 6-24 h incubation, cell proliferation (n = 6) was measured by a colorimetric method. The apoptotic cells (n = 6) were detected by flow cytometry. The expression of p53 protein (n = 3) was determined by SDS-PAGE and Western blotting. RESULTS: Crude LBE (2-5 g/L) and RGE (2-10 g/L) dose-dependently inhibited proliferation of H-4-II-E cells by 11% (P < 0.05) to 85% (P < 0.01) after 6-24 h treatment. Crude LBE at a dose of 5 g/L suppressed cell proliferation of H-4-II-E cells more effectively than crude RGE after 6-24 h incubation (P < 0.01). Crude LBE (2-10 g/L) and RGE (2-5 g/L) also dose-dependently inhibited proliferation of HA22T/VGH cells by 14%-43% (P < 0.01) after 24 h. Crude LBE at a dose of 10 g/L inhibited the proliferation of HA22T/VGH cells more effectively than crude RGE (56.8% ± 1.6% vs 70.3% ± 3.1% of control, P = 0.0003 < 0.01). The apoptotic cells significantly increased in H-4-II-E cells after 24 h treatment with higher doses of crude LBE (2-5 g/L) and RGE (5-10 g/L) (P < 0.01). The expression of p53 protein in H-4-II-E cells was 119% and 143% of the control group compared with the LBE-treated (2, 5 g/L) groups, and 110% and 132% of the control group compared with the RGE -treated (5, 10 g/L) groups after 24 h. CONCLUSION: Hot water-extracted crude LBE (2-5 g/L) and RGE (5-10 g/L) inhibit proliferation and stimulate p53-mediated apoptosis in HCC cells. PMID:16874858

The Capabilities Approach: Fostering contexts for enhancing mental health and wellbeing across the globe.

Science.gov (United States)

White, Ross G; Imperiale, Maria Grazia; Perera, Em

2016-05-05

Concerted efforts have been made in recent years to achieve equity and equality in mental health for all people across the globe. This has led to the emergence of Global Mental Health as an area of study and practice. The momentum that this has created has contributed to the development, implementation and evaluation of services for priority mental disorders in many low- and middle-income countries.This paper discusses two related issues that may be serving to limit the success of mental health initiatives across the globe, and proposes potential solutions to these issues. First, there has been a lack of sophistication in determining what constitutes a 'good outcome' for people experiencing mental health difficulties. Even though health is defined and understood as a state of 'wellbeing' and not merely an absence of illness, mental health interventions tend to narrowly focus on reducing symptoms of mental illness. The need to also focus more broadly on enhancing subjective wellbeing is highlighted. The second limitation relates to the lack of an overarching theoretical framework guiding efforts to reduce inequalities and inequities in mental health across the globe. This paper discusses the potential impact that the Capabilities Approach (CA) could have for addressing both of these issues. As a framework for human development, the CA places emphasis on promoting wellbeing through enabling people to realise their capabilities and engage in behaviours that they subjectively value. The utilization of the CA to guide the development and implementation of mental health interventions can help Global Mental Health initiatives to identify sources of social inequality and structural violence that may impede freedom and individuals' opportunities to realise their capabilities.

Sensor Webs and Virtual Globes: Enabling Understanding of Changes in a partially Glaciated Watershed

Science.gov (United States)

Heavner, M.; Fatland, D. R.; Habermann, M.; Berner, L.; Hood, E.; Connor, C.; Galbraith, J.; Knuth, E.; O'Brien, W.

2008-12-01

The University of Alaska Southeast is currently implementing a sensor web identified as the SouthEast Alaska MOnitoring Network for Science, Telecommunications, Education, and Research (SEAMONSTER). SEAMONSTER is operating in the partially glaciated Mendenhall and Lemon Creek Watersheds, in the Juneau area, on the margins of the Juneau Icefield. These watersheds are studied for both 1. long term monitoring of changes, and 2. detection and analysis of transient events (such as glacier lake outburst floods). The heterogeneous sensors (meteorologic, dual frequency GPS, water quality, lake level, etc), power and bandwidth constraints, and competing time scales of interest require autonomous reactivity of the sensor web. They also present challenges for operational management of the sensor web. The harsh conditions on the glaciers provide additional operating constraints. The tight integration of the sensor web and virtual global enabling technology enhance the project in multiple ways. We are utilizing virtual globe infrastructures to enhance both sensor web management and data access. SEAMONSTER utilizes virtual globes for education and public outreach, sensor web management, data dissemination, and enabling collaboration. Using a PosgreSQL with GIS extensions database coupled to the Open Geospatial Consortium (OGC) Geoserver, we generate near-real-time auto-updating geobrowser files of the data in multiple OGC standard formats (e.g KML, WCS). Additionally, embedding wiki pages in this database allows the development of a geospatially aware wiki describing the projects for better public outreach and education. In this presentation we will describe how we have implemented these technologies to date, the lessons learned, and our efforts towards greater OGC standard implementation. A major focus will be on demonstrating how geobrowsers and virtual globes have made this project possible.

Introducing a New Elementary GLOBE Book on Climate: Supporting Educators and Students in their Understanding of the Concepts Underlying Climate and Climate Change

Science.gov (United States)

Stanitski, D.; Hatheway, B.; Gardiner, L. S.; Taylor, J.; Chambers, L. H.

2016-12-01

Much of the focus on climate literacy in K-12 occurs in middle and high school, where teachers and students can dig into the science in some depth. It is important, however, to introduce this topic at an early age, building on a child's natural curiosity about the world around them - but without overwhelming them with frightening climate change impacts. In some U.S. school systems, a recent focus on standardized testing has crowded out science instruction in order to bring up literacy scores. To give teachers a resource to maintain some science instruction under these conditions, a series of Elementary GLOBE books have been developed. These fictional stories describe sound science and engineering practices that are essential for students to learn the process of science while expanding literacy skills, strongly encouraged in the Next Generation Science Standards (NGSS). The main concepts developed in a new Elementary GLOBE book on climate, titled "What in the World Is Happening to Our Climate?", will be introduced in this presentation. This book complements six other Earth System Science modules within the Elementary GLOBE curriculum and is freely available on the GLOBE website (www.globe.gov/elementaryglobe). The book discusses the concept that climate is changing in different ways and places around the world, and what happens to the climate in one place affects other locations across the globe. Supporting ideas clarify the difference between weather and climate, introduce climate science concepts, reveal the impacts of sea level rise, and help students understand that, while humans are contributing to climate change, they can also participate in solutions that address this challenge. Accompanying teacher's notes and companion classroom activities will be described to help elementary school teachers understand how to approach the subject of climate change with their students.

Physikshow is a hit in the Globe

CERN Multimedia

CERN Bulletin

2010-01-01

Students from the University of Bonn put on three highly successful performances of their "Physikshow", a theatrical journey into the world of particles.   All you need is a bit of imagination and stage management for even the most abstract of physics to become entertaining and intelligible, a principle demonstrated by 20 students from the University of Bonn and their teachers who gave three performances of their "Physikshow" in the Globe of Science and Innovation. The students quickly won over their audience using an array of amazing experiments and wacky sketches to illustrate the world of particles, the principle of forces and the evolution of the cosmos. More than 370 pupils from local secondary schools in France and the Cantons of Geneva and Vaud travelled to CERN for the two performances specially reserved for schools. The audience for the public performance numbered no fewer than 250. Physikshow was first performed in 2002 and has evolved over the years th...

Obstructive Hydrocephalus Secondary to Enlarged Virchow-Robin Spaces: A Rare Cause of Pulsatile Tinnitus.

Science.gov (United States)

Donaldson, Christopher; Chatha, Gurkirat; Chandra, Ronil V; Goldschlager, Tony

2017-05-01

Obstructive hydrocephalus secondary to enlarged Virchow-Robin Spaces (VRS) is a rare entity, with only a few cases reported in the literature. Presenting symptoms vary widely from headaches to dizziness. We report a case of a 31-year-old man who presented with pulsatile tinnitus and magnetic resonance imaging showing obstructive hydrocephalus secondary to tumefactive VRS. After a cerebrospinal fluid diversion procedure in the form of an endoscopic third ventriculostomy, he had almost complete resolution of his symptoms. This is the first case of obstructive hydrocephalus secondary to enlarged VRS, presenting with pulsatile tinnitus. Copyright © 2017 Elsevier Inc. All rights reserved.

CH4 emissions from European Major Population Centers: Results from aircraft-borne CH4 in-situ observations during EMeRGe-Europe campaign 2017

Science.gov (United States)

Roiger, A.; Klausner, T.; Schlager, H.; Ziereis, H.; Huntrieser, H.; Baumann, R.; Eirenschmalz, L.; Joeckel, P.; Mertens, M.; Fisher, R.; Bauguitte, S.; Young, S.; Andrés Hernández, M. D.

2017-12-01

Urban environments represent large and diffuse area sources of CH4 including emissions from pipeline leaks, industrial/sewage treatment plants, and landfills. However, there is little knowledge about the exact magnitude of these emissions and their contribution to total anthropogenic CH4. Especially in the context of an urbanizing world, a better understanding of the methane footprint of urban areas is crucial, both with respect to mitigation and projection of climate impacts. Aircraft-borne in-situ measurements are particularly useful to both quantify emissions from such area sources, as well as to study their impact on the regional distribution. However, airborne CH4 observations downstream of European cities are especially sparse.Here we report from aircraft-borne CH4 in-situ measurements as conducted during the HALO aircraft campaign EMeRGe (Effect of Megacities on the Transport and Transformation of Pollutants on the Regional to Global Scales) in July 2017, which was led by the University of Bremen, Germany. During seven research flights, emissions from a variety of European (Mega)-cities were probed at different altitudes from 3km down to 500m, including measurements in the outflows of London, Rome, Po Valley, Ruhr and Benelux. We will present and compare the CH4 distribution measured downstream of the various studied urban hot-spots. With the help of other trace gas measurements (including e.g. CO2, CO, O3, SO2), observed methane enhancements will be attributed to the different potential source types. Finally, by the combination of in-situ measurements and regional model simulations using the EMAC-MECO(n) model, the contribution of emissions from urban centers to the regional methane budget over Europe will be discussed.

Clinical and Histological Evaluations of Enlarged Facial Skin Pores After Low Energy Level Treatments With Fractional Carbon Dioxide Laser in Korean Patients.

Science.gov (United States)

Kwon, Hyuck Hoon; Choi, Sun Chul; Lee, Won-Yong; Jung, Jae Yoon; Park, Gyeong-Hun

2018-03-01

Enlarged facial pores can be an early manifestation of skin aging and they are a common aesthetic concern for Asians. However, studies of improving the appearance of enlarged pores have been limited. The authors aimed to study the application of CO2 fractional laser treatment in patients with enlarged facial pores. A total of 32 patients with dilated facial pores completed 3 consecutive sessions of low energy level treatments with a fractional CO2 laser at 4-week intervals. Image analysis was performed to calculate the number of enlarged pores before each treatment session and 12 weeks after the final treatment. After application of laser treatments, there was a significant decrease in the number of enlarged pores. The mean number of enlarged pores was decreased by 28.8% after the second session and by 54.5% at post-treatment evaluation. Post-treatment side effects were mild and transitory. Histological and immunohistochemical analyses demonstrated clear increases in the number of collagen fibers and the expression of transforming growth factor-β1. The short-term results showed that treatment with low energy level CO2 fractional laser therapy could be a safe and effective option for patients with Fitzpatrick skin Types III and IV who are concerned with enlarged pores.

Micro‐CT analyses of apical enlargement and molar root canal complexity

DEFF Research Database (Denmark)

Markvart, M.; Darvann, Tron Andre; Larsen, P.

2012-01-01

Markvart M, Darvann TA, Larsen P, Dalstra M, Kreiborg S, Bjørndal L. Micro‐CT analyses of apical enlargement and molar root canal complexity. International Endodontic Journal, 45, 273–281, 2012. Aim To compare the effectiveness of two rotary hybrid instrumentation techniques with focus on apical...

Time Use and Physical Activity: A Shift Away from Movement across the Globe

Science.gov (United States)

Ng, Shu Wen; Popkin, Barry

2012-01-01

Technology linked with reduced physical activity (PA) in occupational work, home/domestic work, and travel and increased sedentary activities, especially television viewing, dominates the globe. Using detailed historical data on time allocation, occupational distributions, energy expenditures data by activity, and time-varying measures of metabolic equivalents of task (MET) for activities when available, we measure historical and current MET by four major PA domains (occupation, home production, travel, and active leisure) and sedentary time among adults (> 18 years). Trends by domain for the United States (1965–2009), the United Kingdom (1961–2005), Brazil (2002–2007), China (1991–2009), and India (2000–2005) are presented. We also project changes in energy expenditure by domain and sedentary time (excluding sleep and personal care) to 2020 and 2030 for each of these countries. The use of previously unexplored detailed time allocation and energy expenditures and other datasets represents a useful addition to our ability to document activity and inactivity globally. Given the potential impact on weight gain and other cardiometabolic health risks, the differential declines in MET of activity and increases in sedentary time across the globe represents a major threat to global health. PMID:22694051

Extremely discrepant mutation spectrum of SLC26A4 between Chinese patients with isolated Mondini deformity and enlarged vestibular aqueduct

OpenAIRE

Huang, Shasha; Han, Dongyi; Yuan, Yongyi; Wang, Guojian; Kang, Dongyang; Zhang, Xin; Yan, Xiaofei; Meng, Xiaoxiao; Dong, Min; Dai, Pu

2011-01-01

Abstract Background Mutations in SLC26A4 cause Pendred syndrome (hearing loss with goiter) or DFNB4 (non-syndromic hearing loss with inner ear malformation, such as enlarged vestibular aqueduct or Mondini deformity). The relationship between mutations in SLC26A4 and Mondini deformity without enlarged vestibular aqueduct has not been studied in any Chinese deaf population. The purpose of this study was to assess whether mutations in the SLC26A4 gene cause Mondini deformity without an enlarged ...

First detailed karyo-morphological analysis and molecular cytological study of leafy cardoon and globe artichoke, two multi-use Asteraceae crops

Directory of Open Access Journals (Sweden)

Debora Giorgi

2016-09-01

Full Text Available Traditionally globe artichoke and leafy cardoon have been cultivated for use as vegetables but these crops are now finding multiple new roles in applications ranging from paper production to cheese preparation and biofuel use, with interest in their functional food potential. So far, their chromosome complements have been poorly investigated and a well-defined karyotype was not available. In this paper, a detailed karyo-morphological analysis and molecular cytogenetic studies were conducted on globe artichoke (Cynara cardunculus Linnaeus, 1753 var. scolymus Fiori, 1904 and leafy cardoon (C. cardunculus Linneaus, 1753 var. altilis De Candolle, 1838. Fluorescent In Situ Hybridization In Suspension (FISHIS was applied to nuclei suspensions as a fast method for screening of labelling probes, before metaphase spread hybridization. Classic Fluorescent In Situ Hybridization (FISH on slide, using repetitive telomeric and ribosomal sequences and Simple Sequence Repeats (SSRs oligonucleotide as probes, identified homologous chromosome relationships and allowed development of molecular karyotypes for both varieties. The close phylogenetic relationship between globe artichoke and cardoon was supported by the very similar karyotypes but clear chromosomal structural variation was detected. In the light of the recent release of the globe artichoke genome sequencing, these results are relevant for future anchoring of the pseudomolecule sequence assemblies to specific chromosomes. In addition, the DNA content of the two crops has been determined by flow cytometry and a fast method for standard FISH on slide and methodological improvements for nuclei isolation are described.

Engaging Citizen Scientists across North America to Monitor Eclipse-driven Environmental Change through NASA GLOBE Observer, Results and Lessons Learned

Science.gov (United States)

Riebeek Kohl, H.; Weaver, K.; Overoye, D.; Martin, A.; Andersen, T.

2017-12-01

How cool was the eclipse? NASA GLOBE Observer challenged citizen scientists across North America to answer that question by observing temperature and cloud changes throughout the August 2017 Total Solar Eclipse. The experiment was meant to chart the impact of changes in solar energy at Earth's surface across all regions that experienced the eclipse, both partial and total. Citizen scientists reported air temperature every 5-10 minutes from first contact to last contact through the free GLOBE Observer app. They also reported cloud cover and cloud type every 15-30 minutes or as changes happened as a proxy for changes in the atmosphere. No data were collected during totality, as we wanted citizen scientists to focus on the eclipse at that time. To recruit citizen scientists, members of the GLOBE Observer Team participated in six large outreach events across the path of totality. We also encouraged participation outside the path of totality though partnerships with informal education institutions and direct communication to the public through NASA communication channels. This presentation will report statistics on citizen science participation and lessons learned about citizen science as an outreach tool. Did participation in the experiment enhance a person's eclipse experience? Did citizen scientists find enough value in the experiment to continue to participate in GLOBE Observer, a long-term citizen science program, after the eclipse? We will also present early results of observed temperature and cloud changes.

QUANTITATIVE HISTOPATHOLOGICAL ANALYSIS OF ENLARGED CELLS DERIVED FROM HUMPBACK GROUPER, Cromileptes altivelis INFECTED WITH GROUPER SLEEPY DISEASE IRIDOVIRUS (GSDIV

Directory of Open Access Journals (Sweden)

Indah Mastuti

2010-12-01

Full Text Available Pathognomonic sign of grouper sleepy disease iridovirus (GSDIV was proposed to be the formation of enlarged cells and necrotic cells, in which under electron microscope, it is revealed to be the inclusion body bearing cells (IBCs and necrotic cells containing GSDIV viral particles. Spleen and kidney tissues are the major sites for formation of enlarged cells. This paper described the result of histopatological analysis of enlarged cells found in the spleen and kidney of moribund fish after GSDIV challenge. A pathogenicity test was conducted on fish stocked in two tanks for infected groups and the other two tanks for uninfected control groups (15 fish per tank. The infected groups were injected intramuscularly with 0.1 ml of the viral inoculum. The uninfected groups were injected with the same amount of EMEM-2. The GSDIV-infected humpback grouper began to die after 6 days post infection and all died after 7 dpi, excluding one fish which had survived until the end of experimental infection periods (93% to 100% mortality. All of the diseased fish showed massive formation of enlarged cells in their spleen, head kidney and trunk kidney. The largest number of enlarged cells was observed on head kidneys and subsequently followed by spleens, trunk kidney (2.0-200.3/field of view. This result suggested that the number of enlarged cells in the affected organs was not the direct factor that led to the mortality of fish.

Stabilizing model predictive control : on the enlargement of the terminal set

NARCIS (Netherlands)

Brunner, F.D.; Lazar, M.; Allgöwer, F.

2015-01-01

It is well known that a large terminal set leads to a large region where the model predictive control problem is feasible without the need for a long prediction horizon. This paper proposes a new method for the enlargement of the terminal set. Different from existing approaches, the method uses the

Left Atrial Enlargement in Young High-Level Endurance Athletes – Another Sign of Athlete’s Heart?

Directory of Open Access Journals (Sweden)

Król Wojciech

2016-12-01

Full Text Available Enlargement of the left atrium is perceived as a part of athlete’s heart syndrome, despite the lack of evidence. So far, left atrial size has not been assessed in the context of exercise capacity. The hypothesis of the present study was that LA enlargement in athletes was physiological and fitness-related condition. In addition, we tried to assess the feasibility and normal values of left atrial strain parameters and their relationship with other signs of athlete’s heart. The study group consisted of 114 international-level rowers (17.5 ± 1.5 years old; 46.5% women. All participants underwent a cardio-pulmonary exercise test and resting transthoracic echocardiography. Beside standard echocardiographic measurements, two dimensional speckle tracking echocardiography was used to assess average peak atrial longitudinal strain, peak atrial contraction strain and early left atrial diastolic longitudinal strain. Mild, moderate and severe left atrial enlargement was present in 27.2°%, 11.4% and 4.4% athletes, respectively. There were no significant differences between subgroups with different range of left atrial enlargement in any of echocardiographic parameters of the left ventricle diastolic function, filling pressure or hypertrophy. A significant correlation was found between the left atrial volume index and maximal aerobic capacity (R > 0.3; p < 0.001. Left atrial strain parameters were independent of atrial size, left ventricle hypertrophy and left ventricle filling pressure. Decreased peak atrial longitudinal strain was observed in 4 individuals (3.5%. We concluded that LA enlargement was common in healthy, young athletes participating in endurance sport disciplines with a high level of static exertion and was strictly correlated with exercise capacity, therefore, could be perceived as another sign of athlete’s heart.

Spinal perimedullary vein enlargement sign: an added value for the differentiation between intradural-extramedullary and intramedullary tumors on magnetic resonance imaging

International Nuclear Information System (INIS)

Gong, Tao; Wang, Guangbin; Gao, Fei; Chen, Xin; Liu, Yubo; Yang, Li; Chen, Weibo

2016-01-01

The purpose of this study was to determine the added value of the perimedullary spinal vein enlargement sign on magnetic resonance imaging (MRI) in distinguishing intradural-extramedullary tumors (IDEMTs) from intramedullary spinal tumors (IMTs). Two hundred and eight consecutive spinal intradural tumors with histopathologic confirmation (21 IMTs, 187 IDEMTs) were enrolled. Two readers blinded to the final pathological diagnosis and clinical data independently assessed the venous enlargement sign to determine the agreement between them and jointly distinguished IDEMTs from IMTs according to the common MRI findings. Sensitivity, specificity, and accuracy for the diagnosis of IDEMTs were calculated for the common MRI findings, vein enlargement sign, and a combination of both. Intraobserver agreement and interobserver agreement for both readers was excellent. The sensitivity, specificity, and accuracy of common MRI findings for differentiating IDEMTs from IMTs were 83.4, 95.2, and 89.3 %, respectively. Thirty-one IDEMTs were mistakenly diagnosed as IMTs, in which seven were cases with vein enlargement signs. By applying the vein enlargement sign to the common MRI findings, the specificity remained at 95.2 %, while the sensitivity improved to 89.3 % and the accuracy increased to 92.3 %. The spinal perimedullary vein enlargement sign is useful in assessing intradural tumors and to differentiate IDEMTs from IMTs. (orig.)

Spinal perimedullary vein enlargement sign: an added value for the differentiation between intradural-extramedullary and intramedullary tumors on magnetic resonance imaging

Energy Technology Data Exchange (ETDEWEB)

Gong, Tao; Wang, Guangbin; Gao, Fei; Chen, Xin [Shandong University, Department of Shandong Medical Imaging Research Institute, Jinan (China); Liu, Yubo [Provincial Hospital Affiliated to Shandong University, Department of Radiology, Jinan (China); Yang, Li [Zhongshan Hospital, Department of Radiology, Shanghai (China); Chen, Weibo [Philips Healthcare, Shanghai (China)

2016-11-15

The purpose of this study was to determine the added value of the perimedullary spinal vein enlargement sign on magnetic resonance imaging (MRI) in distinguishing intradural-extramedullary tumors (IDEMTs) from intramedullary spinal tumors (IMTs). Two hundred and eight consecutive spinal intradural tumors with histopathologic confirmation (21 IMTs, 187 IDEMTs) were enrolled. Two readers blinded to the final pathological diagnosis and clinical data independently assessed the venous enlargement sign to determine the agreement between them and jointly distinguished IDEMTs from IMTs according to the common MRI findings. Sensitivity, specificity, and accuracy for the diagnosis of IDEMTs were calculated for the common MRI findings, vein enlargement sign, and a combination of both. Intraobserver agreement and interobserver agreement for both readers was excellent. The sensitivity, specificity, and accuracy of common MRI findings for differentiating IDEMTs from IMTs were 83.4, 95.2, and 89.3 %, respectively. Thirty-one IDEMTs were mistakenly diagnosed as IMTs, in which seven were cases with vein enlargement signs. By applying the vein enlargement sign to the common MRI findings, the specificity remained at 95.2 %, while the sensitivity improved to 89.3 % and the accuracy increased to 92.3 %. The spinal perimedullary vein enlargement sign is useful in assessing intradural tumors and to differentiate IDEMTs from IMTs. (orig.)

Genome-Wide Identification of BAHD Acyltransferases and In vivo Characterization of HQT-like Enzymes Involved in Caffeoylquinic Acid Synthesis in Globe Artichoke

Science.gov (United States)

Moglia, Andrea; Acquadro, Alberto; Eljounaidi, Kaouthar; Milani, Anna M.; Cagliero, Cecilia; Rubiolo, Patrizia; Genre, Andrea; Cankar, Katarina; Beekwilder, Jules; Comino, Cinzia

2016-01-01

Globe artichoke (Cynara cardunculus L. var. scolymus) is a rich source of compounds promoting human health (phytonutrients), among them caffeoylquinic acids (CQAs), mainly represented by chlorogenic acid (CGA), and dicaffeoylquinic acids (diCQAs). The enzymes involved in their biosynthesis belong to the large family of BAHD acyltransferases. Following a survey of the globe artichoke genome, we identified 69 BAHD proteins carrying the catalytic site (HXXXD). Their phylogenetic analysis together with another 43 proteins, from 21 species, representative of the BAHD family, highlighted their grouping in seven major clades. Nine globe artichoke acyltransferases clustered in a sub-group of Clade V, with 3 belonging to hydroxycinnamoyl-CoA:quinate hydroxycinnamoyl transferase (HQT) and 2 to hydroxycinnamoyl-CoA:shikimate/quinate hydroxycinnamoyl transferase (HCT) like proteins. We focused our attention on the former, HQT1, HQT2, and HQT3, as they are known to play a key role in CGA biosynthesis. The expression of genes coding for the three HQTs and correlation of expression with the CQA content is reported for different globe artichoke tissues. For the first time in the globe artichoke, we developed and applied the virus-induced gene silencing approach with the goal of assessing in vivo the effect of HQT1 silencing, which resulted in a marked reduction of both CGA and diCQAs. On the other hand, when the role of the three HQTs was assessed in leaves of Nicotiana benthamiana through their transient overexpression, significant increases in mono- and diCQAs content were observed. Using transient GFP fusion proteins expressed in N. benthamiana leaves we also established the sub-cellular localization of these three enzymes. PMID:27721818

Eyeball Position in Facial Approximation: Accuracy of Methods for Predicting Globe Positioning in Lateral View.

Science.gov (United States)

Zednikova Mala, Pavla; Veleminska, Jana

2018-01-01

This study measured the accuracy of traditional and validated newly proposed methods for globe positioning in lateral view. Eighty lateral head cephalograms of adult subjects from Central Europe were taken, and the actual and predicted dimensions were compared. The anteroposterior eyeball position was estimated as the most accurate method based on the proportion of the orbital height (SEE = 1.9 mm) and was followed by the "tangent to the iris method" showing SEE = 2.4 mm. The traditional "tangent to the cornea method" underestimated the eyeball projection by SEE = 5.8 mm. Concerning the superoinferior eyeball position, the results showed a deviation from a central to a more superior position by 0.3 mm, on average, and the traditional method of central positioning of the globe could not be rejected as inaccurate (SEE = 0.3 mm). Based on regression analyzes or proportionality of the orbital height, the SEE = 2.1 mm. © 2017 American Academy of Forensic Sciences.

Lagochilascariasis leading to severe involvement of ocular globes, ears and meninges.

Science.gov (United States)

Aquino, Renata T R; Magliari, Maria E R; Vital Filho, José; Silva, Maria A L G; Lima, Carlos A da Conceição; Rocha, Antonio J; Silva, Carlos J; Rewin, Jonathan A; Nahas, Tatiana R; Chieffi, Pedro Paulo

2008-01-01

A case report of a 31 year-old woman from Paraíba State (North-Eastern Brazil) that presented severe involvement of ocular globes, ears and meninges. Diagnosis was established after enucleation of her left eye, when adult worms were seen in the midst of a granulomatous inflammatory process. Her response to the initial treatment with levamisole and cambendazole was good, but there was a relapse after the fifth month of treatment even with maintenance doses of both medications. She later received ivermectin and albendazol and responded well.

An Optimization Method for Virtual Globe Ocean Surface Dynamic Visualization

Directory of Open Access Journals (Sweden)

HUANG Wumeng

2016-12-01

Full Text Available The existing visualization method in the virtual globe mainly uses the projection grid to organize the ocean grid. This special grid organization has the defects in reflecting the difference characteristics of different ocean areas. The method of global ocean visualization based on global discrete grid can make up the defect of the projection grid method by matching with the discrete space of the virtual globe, so it is more suitable for the virtual ocean surface simulation application.But the available global discrete grids method has many problems which limiting its application such as the low efficiency of rendering and loading, the need of repairing grid crevices. To this point, we propose an optimization for the global discrete grids method. At first, a GPU-oriented multi-scale grid model of ocean surface which develops on the foundation of global discrete grids was designed to organize and manage the ocean surface grids. Then, in order to achieve the wind-drive wave dynamic rendering, this paper proposes a dynamic wave rendering method based on the multi-scale ocean surface grid model to support real-time wind field updating. At the same time, considering the effect of repairing grid crevices on the system efficiency, this paper presents an efficient method for repairing ocean surface grid crevices based on the characteristics of ocean grid and GPU technology. At last, the feasibility and validity of the method are verified by the comparison experiment. The experimental results show that the proposed method is efficient, stable and fast, and can compensate for the lack of function of the existing methods, so the application range is more extensive.

Proposal for the award of a contract for the wood construction work for the Globe of Innovation project

CERN Document Server

2003-01-01

This document concerns the award of a contract for the wood construction work for the Globe of Innovation project. A call for tenders (IT-3260/ST/GIR) was sent on 31 October 2003 to twelve firms in one Member State. By the closing date, CERN had received five tenders from four firms and one consortium. The Finance Committee is invited to agree to the negotiation of a contract with CIB (CH), the lowest bidder, for the wood construction work for the Globe of Innovation project for an estimated amount not exceeding 820 000 Swiss francs, not subject to revision. The firm has indicated the following distribution by country of the contract value covered by this adjudication proposal: CH - 100%.

NATO Enlargement and the National Agendas of America, Great Britain, France, and Germany

National Research Council Canada - National Science Library

Irving, William

1997-01-01

This thesis examines the enlargement of NATO from the collapse of the Warsaw Pact and the Soviet Union, through the formation of the North Atlantic Cooperation Council and the Partnership for Peace...

Reversible and non-reversible enlargement of cerebral spinal fluid spaces in anorexia nervosa

International Nuclear Information System (INIS)

Artmann, H.; Grau, H.; Adelmann, M.; Schleiffer, R.

1985-01-01

Brain CT studies of 35 patients with anoxia nervosa confirmed the observations of other authors: cerebral dystrophic changes correlate with weight loss and the reversibility of these changes also correlates with the normalization of body weight. Other corroborated facts are: the most numerous and most pronounced enlargements are of the cortical sulci and the interhemispheric fissure, moderate widening affects the ventricles and the rarest and most insignificant changes are those of the cerebellum. The reversibility of the changes showed a parallel to the extent of the changes themselves and to the duration of improvement of the body weight. The reversibility of the enlargement of the cortical sulci and of the distances between the frontal horns of the lateral ventricles was more often significant than that of the abnormal measurements of the cella media. This difference is based on minimal early acquired brain damage which occurs in 60% of our patients. This high incidence of early acquired minimal brain disease in patients with anorexia nervosa is here discussed as a nonspecific predisposing factor. Although there is no exact explanation of the etiology of the reversible enlargement of cerenral spinal fluid (CSF) spaces in anorexia nervosa, the changes resemble those in alcoholics. The mechanisms of brain changes in alcoholism, as shown experimentally, seem to us to throw light on the probable mechanism of reversible dystrophic brain changes in anorexia nervosa. (orig.)

Reversible and non-reversible enlargement of cerebral spinal fluid spaces in anorexia nervosa

Energy Technology Data Exchange (ETDEWEB)

Artmann, H.; Grau, H.; Adelmann, M.; Schleiffer, R.

1985-07-01

Brain CT studies of 35 patients with anoxia nervosa confirmed the observations of other authors: cerebral dystrophic changes correlate with weight loss and the reversibility of these changes also correlates with the normalization of body weight. Other corroborated facts are: the most numerous and most pronounced enlargements are of the cortical sulci and the interhemispheric fissure, moderate widening affects the ventricles and the rarest and most insignificant changes are those of the cerebellum. The reversibility of the changes showed a parallel to the extent of the changes themselves and to the duration of improvement of the body weight. The reversibility of the enlargement of the cortical sulci and of the distances between the frontal horns of the lateral ventricles was more often significant than that of the abnormal measurements of the cella media. This difference is based on minimal early acquired brain damage which occurs in 60% of our patients. This high incidence of early acquired minimal brain disease in patients with anorexia nervosa is here discussed as a nonspecific predisposing factor. Although there is no exact explanation of the etiology of the reversible enlargement of cerenral spinal fluid (CSF) spaces in anorexia nervosa, the changes resemble those in alcoholics. The mechanisms of brain changes in alcoholism, as shown experimentally, seem to us to throw light on the probable mechanism of reversible dystrophic brain changes in anorexia nervosa.

Enlarged cavum septum pellucidum as a neurodevelopmental marker in adolescent-onset opiate dependence.

Directory of Open Access Journals (Sweden)

Jaeuk Hwang

Full Text Available Adolescent-onset exposure to highly addictive substances such as opiates may induce far-reaching deleterious effects on later mental and physical health. However, little is known about the neurodevelopmental basis for adolescent-onset opiate dependence. Here we examined whether having an abnormally large cavum septum pellucidum (CSP, a putative marker of limbic structural maldevelopment, is associated with opiate dependence particularly beginning in adolescence.The overall length of the CSP and the prevalence of abnormal enlargement of the CSP were assessed and compared in 65 opiate-dependent subjects (41 adolescent-onset opiate users and 24 adult-onset opiate users and 67 healthy subjects.Opiate-dependent subjects showed a greater prevalence of abnormal CSP enlargement relative to healthy subjects (odds ratio [OR]=3.64, p=0.034. The overall CSP length of adolescent-onset opiate-dependent subjects was greater, as compared not only with healthy subjects (F₁,₁₀₄=11.03, p=0.001 but also with those who began opiate use during adulthood (F₁,₆₁=4.43, p=0.039.The current findings provide the first evidence that abnormal CSP enlargement, which reflects limbic system dysgenesis of neurodevelopmental origin, may be linked to later development of opiate dependence. In addition, a greater CSP length, which indicates more severe limbic abnormalities, appears to confer higher risk for earlier onset of opiate use.

Protective effect of Korean Red Ginseng extract against Helicobacter pylori-induced gastric inflammation in Mongolian gerbils

Directory of Open Access Journals (Sweden)

Minkyung Bae

2014-01-01

Full Text Available Helicobacter pylori-induced gastric inflammation includes induction of inflammatory mediators interleukin (IL-8 and inducible nitric oxide synthase (iNOS, which are mediated by oxidant-sensitive transcription factor NF-κB. High levels of lipid peroxide (LPO and increased activity of myeloperoxidase (MPO, a biomarker of neutrophil infiltration, are observed in H. pylori-infected gastric mucosa. Panax ginseng Meyer, a Korean herb medicine, is widely used in Asian countries for its biological activities including anti-inflammatory efficacy. The present study aims to investigate whether Korean Red Ginseng extract (RGE inhibits H. pylori-induced gastric inflammation in Mongolian gerbils. One wk after intragastric inoculation with H. pylori, Mongolian gerbils were fed with either the control diet or the diet containing RGE (200 mg RGE/gerbil for 6 wk. The following were determined in gastric mucosa: the number of viable H. pylori in stomach; MPO activity; LPO level; mRNA and protein levels of keratinocyte chemoattractant factor (KC, a rodent IL-8 homolog, IL-1β, and iNOS; protein level of phospho-IκBα (which reflects the activation of NF-κB; and histology. As a result, RGE suppressed H. pylori-induced mRNA and protein levels of KC, IL-1β, and iNOS in gastric mucosa. RGE also inhibited H. pylori-induced phosphorylation of IκBα and increases in LPO level and MPO activity of gastric mucosa. RGE did not affect viable H. pylori colonization in the stomach, but improved the histological grade of infiltration of polymorphonuclear neutrophils, intestinal metaplasia, and hyperplasia. In conclusion, RGE inhibits H. pylori-induced gastric inflammation by suppressing induction of inflammatory mediators (KC, IL-1β, iNOS, MPO activity, and LPO level in H. pylori-infected gastric mucosa.

An anatomic risk model to screen post endovascular aneurysm repair patients for aneurysm sac enlargement.

Science.gov (United States)

Png, Chien Yi M; Tadros, Rami O; Beckerman, William E; Han, Daniel K; Tardiff, Melissa L; Torres, Marielle R; Marin, Michael L; Faries, Peter L

2017-09-01

Follow-up computed tomography angiography (CTA) scans add considerable postimplantation costs to endovascular aneurysm repairs (EVARs) of abdominal aortic aneurysms (AAAs). By building a risk model, we hope to identify patients at low risk for aneurysm sac enlargement to minimize unnecessary CTAs. 895 consecutive patients who underwent EVAR for AAA were reviewed, of which 556 met inclusion criteria. A Probit model was created for aneurysm sac enlargement, with preoperative aneurysm morphology, patient demographics, and operative details as variables. Our final model included 287 patients and had a sensitivity of 100%, a specificity of 68.9%, and an accuracy of 70.4%. Ninety-nine (35%) of patients were assigned to the high-risk group, whereas 188 (65%) of patients were assigned to the low-risk group. Notably, regarding anatomic variables, our model reported that age, pulmonary comorbidities, aortic neck diameter, iliac artery length, and aneurysms were independent predictors of post-EVAR sac enlargement. With the exception of age, all statistically significant variables were qualitatively supported by prior literature. With regards to secondary outcomes, the high-risk group had significantly higher proportions of AAA-related deaths (5.1% versus 1.1%, P = 0.037) and Type 1 endoleaks (9.1% versus 3.2%, P = 0.033). Our model is a decent predictor of patients at low risk for post AAA EVAR aneurysm sac enlargement and associated complications. With additional validation and refinement, it could be applied to practices to cut down on the overall need for postimplantation CTA. Copyright © 2017 Elsevier Inc. All rights reserved.

Primary tuberculous gingival enlargement - A rare clinical entity: Case report and brief review of the literature

Directory of Open Access Journals (Sweden)

Suhail Majid Jan

2014-01-01

Full Text Available Tuberculosis (TB is a chronic specific granulomatous disease and a major cause of death in developing countries. The clinical presentation of TB lesions of the oral cavity varies widely and can manifest as ulcerations, diffuse inflammatory lesions, granulomas and fissures. Oral lesions generally appear secondary to primary TB infection elsewhere, although primary infection of the oral mucosa by Mycobacterium tuberculosis has also been described. We hereby report a case of primary TB of the gingiva manifesting as gingival enlargement. Diagnosis was based on histopathological examination, complete blood count, X-ray chest and immunological investigations with detection of antibodies against M. tuberculosis. Anti-tuberculous therapy was carried out for over 6 months and was followed by surgical excision of the residual enlargement under local anesthesia. After 1-year follow-up, there was no recurrence of the disease. This case report emphasizes the need for dentists to include TB in the differential diagnosis of various types of gingival enlargements.

Cell enlargement of plant tissue explants oscillates with a temperature-compensated period of ca. 24 min

Science.gov (United States)

Morre, D. James; Ternes, Philipp; Morre, Dorothy M.

2002-01-01

Rate of plant cell enlargement, measured at intervals of 3 min using a sensitive linear transducer, oscillates with a minimum period of about 24 min that parallels the 24-min periodicity observed with the oxidation of NADH by the external plasma membrane NADH oxidase and of single cells measured previously by video-enhanced light microscopy. Also exhibiting 24-min oscillations is the steady-state rate of cell enlargement induced by the addition of the auxin herbicide 2,4-dichlorophenoxyacetic acid (2,4-D) or the natural auxin indole-3-acetic acid (IAA). Immediately following 2,4-D addition, a very complex pattern of oscillations is frequently observed. However, after several hours a dominant 24-min period emerges. The length of the 24-min period is temperature compensated and remains constant at 24 min when measured at 15, 25 or 35 degrees C, despite the fact that the rate of cell enlargement approximately doubles for each 10 degree C rise over this same range of temperatures.

Physicochemical and Sensory Properties of Red Ginseng Extracts or Red Ginseng Hydrolyzates-added Asiago Cheese during Ripening

Directory of Open Access Journals (Sweden)

Kyung-Hoon Choi

2015-01-01

Full Text Available This study was carried out to investigate physicochemical properties of different concentrations (0.1%, 0.3%, and 0.5% of red ginseng hydrolyzates (RGH- or red ginseng extract (RGE-added Asiago cheeses (AC during ripening at 14°C for 4 months. The moisture content significantly increased with increasing concentrations of both RGH- and RGE- added AC (p<0.05. While RGHAC and RGEAC were more yellow and darker with increasing concentrations than that of control (p<0.05, the color was not influenced from the hydrolysis. In texture analysis, hardness, cohesiveness, and chewiness of RGHAC and RGEAC significantly decreased compared to the control during the ripening (p<0.05. In sensory analysis, bitterness and ginseng flavor and taste scores increased significantly with increasing the concentrations of RGH and RGE during ripening (p<0.05. In conclusion, the addition of RGH and RGE into cheese slightly influenced the properties of Asiago cheese, and similarities were observed between RGHAC and RGEAC. Thus, the lower concentrations (0.1% to 0.3% of RGH and RGE added to AC were preferred for color, texture, and sensory during the ripening, therefore, these cheeses would be worth developing commercially.

Using Digital Globes to Explore the Deep Sea and Advance Public Literacy in Earth System Science

Science.gov (United States)

Beaulieu, S. E.; Brickley, A.; Emery, M.; Spargo, A.; Patterson, K.; Joyce, K.; Silva, T.; Madin, K.

2014-12-01

Digital globes are new technologies increasingly used in both informal and formal education to display global datasets. By creating a narrative using multiple datasets, linkages between Earth systems - lithosphere, hydrosphere, atmosphere, and biosphere - can be conveyed. But how effective are digital globes in advancing public literacy in Earth system science? We addressed this question in developing new content for digital globes that interweaves imagery obtained by deep-diving vehicles with global datasets, including a new dataset locating the world's known hydrothermal vents. Our two narratives, "Life Without Sunlight" (LWS) and "Smoke and Fire Underwater" (SFU), each focus on STEM (science, technology, engineering, and mathematics) principles related to geology, biology, and exploration. We are preparing a summative evaluation for our content delivered on NOAA's Science on a Sphere as interactive presentations and as movies. We tested knowledge gained with respect to the STEM principles and the level of excitement generated by the virtual deep-sea exploration. We conducted a Post-test Only Design with quantitative data based on self-reporting on a Likert scale. A total of 75 adults and 48 youths responded to our questionnaire, distributed into test groups that saw either one of the two narratives delivered either as a movie or as an interactive presentation. Here, we report preliminary results for the youths, the majority (81%) of which live in towns with lower income and lower levels of educational attainment as compared to other towns in Massachusetts. For both narratives, there was knowledge gained for all 6 STEM principles and "Quite a Bit" of excitement. The mode in responses for knowledge gained was "Quite a Bit" for both the movie and the interactive presentation for 4 of the STEM principles (LWS geology, LWS biology, SFU geology, and SFU exploration) and "Some" for SFU biology. Only for LWS exploration was there a difference in mode between the

Thursday Programme of CineGlobe Festival 2015

CERN Multimedia

Cugini, Pavel

2015-01-01

The CineGlobe Programme on Thursday 26th March 2015 counted with two short-films inspired by science sessions, two workshops on the 360 degree dome, and a special evening show in collaboration with the Mapping Festival, to celebrate the UNESCO Year of Light. The evening open with Diego Blas, CERN theorist, talking about Light, Einstein and the LHC to celebrate the UNESCO International Year of Light. Followed by a performance by the artist YRO_EILE_18. The artist Yro presents Eile, a live installation performance where light, sound, and cinema converge to tell a timeless story. EILE is a live cinema performance, in which yro makes live sound and images with a camera, some microphones and small objects like stones, balls, bits of paper and string.These materials allow him to create videos and sound, which aesthetics are close to abstract cinema and object theater assembled, sampled and grinded . The process is part of the staging itself as well as the film that results. Indescribable Eile is lived as an experie...

Events at the Globe of Science and Innovation

CERN Multimedia

2006-01-01

CERN is organising a series of lectures based on the exhibition À des années lumière... Thursday 7 December, 8.00 p.m. (in French) 'A look at Einstein and physics from the different perspectives of a physicist and an illustrator' John Ellis, CERN physicist, and Fiami, author of the comic book 'The Lives of Einstein' Come and explore physics with a comic book author who will present six vital episodes in the history of knowledge in the company of his hero, Albert Einstein. After this literary voyage of discovery, a CERN physicist will explain the issues facing physics today, more than a century after Einstein's miracle year. There will be a book signing session with Fiami at the end of the talk www.fiami.ch Lecture for the general public By reservation only: + 41 (0)22 767 76 76 Information on future meetings : www.cern.ch/globe

Management of phenytoin-induced gingival enlargement in a patient with antiphospholipid antibody syndrome: A rare case report

Directory of Open Access Journals (Sweden)

Shilpa Sarvesh Urolagin

2016-01-01

Full Text Available Antiphospholipid antibody (APLA syndrome is a noninflammatory autoimmune disease, with innumerable clinical manifestations ranging from recurrent thrombosis and pregnancy morbidity to valvular lesions, transverse myelitis, thrombocytopenia, and hemolytic anemia. APLAs in antiphospholipid syndrome (APS are well-known risk factors for cerebrovascular accidents. Stroke is the most common manifestation of APS in the central nervous system. Gingival enlargement is a known side effect of phenytoin which is an antiepileptic drug. This can have a significant effect on the quality of life as well as increasing the oral bacterial load by generating plaque retention sites. The management of gingival overgrowth seems to be directed at controlling gingival inflammation through a good oral hygiene regimen. Thus, this case report aims to describe the conservative management of phenytoin-induced gingival enlargement combined with inflammatory enlargement in a patient with APLA syndrome.

Use of GLOBE Observations to Derive a Landsat 8 Split Window Algorithm for Urban Heat Island

Science.gov (United States)

Fagerstrom, L.; Czajkowski, K. P.

2017-12-01

Surface temperature has been studied to investigate the warming of urban climates, also known as urban heat islands, which can impact urban planning, public health, pollution levels, and energy consumption. However, the full potential of remotely sensed images is limited when analyzing land surface temperature due to the daunting task of correcting for atmospheric effects. Landsat 8 has two thermal infrared sensors. With two bands in the infrared region, a split window algorithm (SWA), can be applied to correct for atmospheric effects. This project used in situ surface temperature measurements from NASA's ground observation program, the Global Learning and Observations to Benefit the Environment (GLOBE), to derive the correcting coefficients for use in the SWA. The GLOBE database provided land surface temperature data that coincided with Landsat 8 overpasses. The land surface temperature derived from Landsat 8 SWA can be used to analyze for urban heat island effect.

Le Palais de l'Equilibre se mue en Globe de l'Innovation le canton pourrait aussi financer son aménagement sur la route de Meyrin

CERN Multimedia

Jan-Hess, Isabel

2003-01-01

Plans for the new Globe of Innovation have finally been agreed. It will be sited opposite the entrance to CERN along with a second building for conferences and meetings. The Globe will be used for welcoming visitors. The Geneva Canton could also finance its installation in Meyrin (2 pages)

Principles of veterinary radiography. 2. rev. and enlarged ed.

International Nuclear Information System (INIS)

Douglas, S.W.; Herrtage, M.E.; Williamson, H.D.

1991-01-01

This book by Douglas and Williamson about the physical-technical fundamentals of radiology in veterinary medicine was first published in 1977 and the second edition now available has been revised and enlarged. Part 1 gives coverage of the basic physical and technical requirements of the necessary equipment and installations as well as the laws governing radiation protection. In Part 2, exposure techniques and special examinations procedures are described in detail. Contrast-enhanced examinations are dealt with exhaustively. (orig./MG) With 166 figs., 10 tabs [de

Mapping farm animal welfare research in an enlarged Europe

DEFF Research Database (Denmark)

Kirchner, Marlene K.; Košťál, Ľubor; Bilčík, Boris

2017-01-01

Against the background of divergent political developments across Europe, farm animal welfare (FAW) science has evolved during the last three decades as an inter-disciplinary research area. Recent achievements include pan-European research projects and the implementation of animal welfare...... on questionnaires sent out to a wide researcher network in regions of an enlarged Europe, we found differences with regard to ‘input factors’ such as human resources, animal and laboratory facilities and national and international research funding and ‘output factors’ such as inter/national collaboration...

Nontumorous enlargement of the internal auditory canal. A risk factor for sensorineural hearing loss? A high resolution CT-study

Energy Technology Data Exchange (ETDEWEB)

Stimmer, H.; Rummeny, E.J. [Technical University Munich, Klinikum rechts der Isar (Germany). Dept. of Radiology; Niedermeyer, H.P. [Technical University Munich, Klinikum rechts der Isar (Germany). ENT-Clinic; Kehl, V. [Technical University Munich, Klinikum rechts der Isar (Germany). Inst. for Medical Statistics and Epidemiology

2015-06-15

First aim of the study was to define normal shape and diameter of the internal auditory canal (IAC). In the second part the clinical relevance of IAC-enlargement was analyzed, considering also lesions of the subtle structures at the fundus of the internal auditory canal. 440 high resolution CT-scans of the temporal bone were used for retrospective analysis of the internal auditory canal and its fundus region. The mean value of the IAC diameter in axial and coronal plane was determined. In 20 of 440 patients IAC enlargement was found. In the group with pronounced enlargement (3fold SD) nearly all patients suffered from hearing impairment. In some of them we found structural abnormalities near the IAC fundus in the CSF/perilymph border zone. A new CT-based definition of normal shape and diameter of the internal auditory canal is presented. There is some evidence that a pathologic transmission of CSF-pressure in case of IAC-enlargement and/or abnormal fistulous communications could play an important role in the pathophysiology of hearing loss.

Mediastinal lymph node enlargement in patients with valvular heart disease: CT evaluation and clinical correlation

International Nuclear Information System (INIS)

Park, Hye Ju; Jung, Jung Im; Ahn, Myeong Im; Han, Dae Hee; Park, Seog Hee

2016-01-01

To evaluate the presence, size and location of enlarged mediastinal lymph nodes (LNs) in patients with valvular heart disease (VHD) using computed tomography scans in correlation with ejection fraction (EF). We retrospectively evaluated 30 patients with VHD, without pre-existing diseases that could cause lymphadenopathy (LAP). The presence, size, and location of LNs greater than 1 cm in short axis diameter were evaluated. The location of mediastinal LNs was recorded according to the International Association for the Study of Lung Cancer. Furthermore, we evaluated the presence of pulmonary edema, pleural effusion, and other thoracic abnormalities and evaluated EF of the heart on transthoracic echocardiography. Sixteen patients (53%) had at least 1 enlarged mediastinal LN. The most frequent locations were lower paratracheal (4R, n = 8/4L, n = 6), subcarinal (7, n = 5) and right upper paratracheal (2R, n = 4) regions. The frequency of mediastinal LAP was higher in patients with aortic regurgitation (2 of 2, 100%) followed by mitral regurgitation (8 of 11, 73%); it was also high in patients with pulmonary edema (80%), pleural effusion (81%), or both (77%), as compared to patients without pulmonary edema or pleural effusion (17%) (p = 0.001). Ten of 30 patients showed an abnormal EF of < 55%; among them, 8 had mediastinal LAP. However, the relationship between EF and LAP was not statistically significant (p = 0.058). Mediastinal LN enlargement is common in patients with VHD, especially in cases of pulmonary edema and pleural effusion. Enlarged mediastinal LNs were frequently observed with abnormal EF, however, the relationship between EF and mediastinal LAP was not statistically significant.

Mediastinal lymph node enlargement in patients with valvular heart disease: CT evaluation and clinical correlation

Energy Technology Data Exchange (ETDEWEB)

Park, Hye Ju; Jung, Jung Im; Ahn, Myeong Im; Han, Dae Hee; Park, Seog Hee [Dept. of Radiology, Seoul St. Mary' s Hospital, College of Medicine, The Catholic University of Korea, Seoul (Korea, Republic of)

2016-04-15

To evaluate the presence, size and location of enlarged mediastinal lymph nodes (LNs) in patients with valvular heart disease (VHD) using computed tomography scans in correlation with ejection fraction (EF). We retrospectively evaluated 30 patients with VHD, without pre-existing diseases that could cause lymphadenopathy (LAP). The presence, size, and location of LNs greater than 1 cm in short axis diameter were evaluated. The location of mediastinal LNs was recorded according to the International Association for the Study of Lung Cancer. Furthermore, we evaluated the presence of pulmonary edema, pleural effusion, and other thoracic abnormalities and evaluated EF of the heart on transthoracic echocardiography. Sixteen patients (53%) had at least 1 enlarged mediastinal LN. The most frequent locations were lower paratracheal (4R, n = 8/4L, n = 6), subcarinal (7, n = 5) and right upper paratracheal (2R, n = 4) regions. The frequency of mediastinal LAP was higher in patients with aortic regurgitation (2 of 2, 100%) followed by mitral regurgitation (8 of 11, 73%); it was also high in patients with pulmonary edema (80%), pleural effusion (81%), or both (77%), as compared to patients without pulmonary edema or pleural effusion (17%) (p = 0.001). Ten of 30 patients showed an abnormal EF of < 55%; among them, 8 had mediastinal LAP. However, the relationship between EF and LAP was not statistically significant (p = 0.058). Mediastinal LN enlargement is common in patients with VHD, especially in cases of pulmonary edema and pleural effusion. Enlarged mediastinal LNs were frequently observed with abnormal EF, however, the relationship between EF and mediastinal LAP was not statistically significant.

Association of prothrombin complex concentrate administration and hematoma enlargement in non-vitamin K antagonist oral anticoagulant-related intracerebral hemorrhage.

Science.gov (United States)

Gerner, Stefan T; Kuramatsu, Joji B; Sembill, Jochen A; Sprügel, Maximilian I; Endres, Matthias; Haeusler, Karl Georg; Vajkoczy, Peter; Ringleb, Peter A; Purrucker, Jan; Rizos, Timolaos; Erbguth, Frank; Schellinger, Peter D; Fink, Gereon R; Stetefeld, Henning; Schneider, Hauke; Neugebauer, Hermann; Röther, Joachim; Claßen, Joseph; Michalski, Dominik; Dörfler, Arnd; Schwab, Stefan; Huttner, Hagen B

2018-01-01

To investigate parameters associated with hematoma enlargement in non-vitamin K antagonist oral anticoagulant (NOAC)-related intracerebral hemorrhage (ICH). This retrospective cohort study includes individual patient data for 190 patients with NOAC-associated ICH over a 5-year period (2011-2015) at 19 departments of neurology across Germany. Primary outcome was the association of prothrombin complex concentrate (PCC) administration with hematoma enlargement. Subanalyses were calculated for blood pressure management and its association with the primary outcome. Secondary outcomes include associations with in-hospital mortality and functional outcome at 3 months assessed using the modified Rankin Scale. The study population for analysis of primary and secondary outcomes consisted of 146 NOAC-ICH patients with available follow-up imaging. Hematoma enlargement occurred in 49/146 (33.6%) patients with NOAC-related ICH. Parameters associated with hematoma enlargement were blood pressure ≥ 160mmHg within 4 hours and-in the case of factor Xa inhibitor ICH-anti-Xa levels on admission. PCC administration prior to follow-up imaging was not significantly associated with a reduced rate of hematoma enlargement either in overall NOAC-related ICH or in patients with factor Xa inhibitor intake (NOAC: risk ratio [RR] = 1.150, 95% confidence interval [CI] = 0.632-2.090; factor Xa inhibitor: RR = 1.057, 95% CI = 0.565-1.977), regardless of PCC dosage given or time interval until imaging or treatment. Systolic blood pressure levels < 160mmHg within 4 hours after admission were significantly associated with a reduction in the proportion of patients with hematoma enlargement (RR = 0.598, 95% CI = 0.365-0.978). PCC administration had no effect on mortality and functional outcome either at discharge or at 3 months. In contrast to blood pressure control, PCC administration was not associated with a reduced rate of hematoma enlargement in NOAC-related ICH

Revitalizing Indigenous Languages, Cultures, and Histories in Montana, across the United States and around the Globe

Science.gov (United States)

Carjuzaa, Jioanna

2017-01-01

Many educators have sung the praises of Indian Education for All, Montana's constitutional mandate, and heard the successes of Montana's Indigenous language revitalization efforts which reverberate around the globe. Teaching Indigenous languages is especially, challenging since there are limited numbers of fluent speakers and scarce resources…

Enlarged clitoris in wild polar bears (Ursus maritimus) can be misdiagnosed as pseudohermaphroditism

DEFF Research Database (Denmark)

Sonne, C.; Leifsson, Páll Skuli; Dietz, R.

2005-01-01

A 23-year-old female polar bear (Ursus maritimus) killed in an Inuit hunt in East Greenland on July 9, 1999 had a significantly enlarged clitoris resembling, in size, form and colour, those of previously reported 'pseudohermaphroditic' polar bears from Svalbard. It has been suggested that an enzyme...... and internal reproductive organs of the present were similar to a reference group of 23 normal adult female polar bears from East Greenland collected in 1999-2002. The aberrant bear was a female genotype, and macroscopic examination of her internal reproductive organs indicated that she was reproductively....... It is hence possible that the previously reported adult female polar bear pseudohermaphrodites from Svalbard are in fact misdiagnoses. Therefore, future studies examining pseudohermaphroditism in wildlife should consider that certain occurrences are natural events, e.g., enlarged clitoris in the present East...

Can axial-based nodal size criteria be used in other imaging planes to accurately determine "enlarged" head and neck lymph nodes?

Science.gov (United States)

Bartlett, Eric S; Walters, Thomas D; Yu, Eugene

2013-01-01

Objective. We evaluate if axial-based lymph node size criteria can be applied to coronal and sagittal planes. Methods. Fifty pretreatment computed tomographic (CT) neck exams were evaluated in patients with head and neck squamous cell carcinoma (SCCa) and neck lymphadenopathy. Axial-based size criteria were applied to all 3 imaging planes, measured, and classified as "enlarged" if equal to or exceeding size criteria. Results. 222 lymph nodes were "enlarged" in one imaging plane; however, 53.2% (118/222) of these were "enlarged" in all 3 planes. Classification concordance between axial versus coronal/sagittal planes was poor (kappa = -0.09 and -0.07, resp., P planes. Conclusion. Classification of "enlarged" lymph nodes differs between axial versus coronal/sagittal imaging planes when axial-based nodal size criteria are applied independently to all three imaging planes, and exclusively used without other morphologic nodal data.

What's a Nice Hummingbird Like You Doing at an AGU Meeting Like This? (or, Operation RubyThroat Meets The GLOBE Program)

Science.gov (United States)

Hilton, B.

2003-12-01

"Operation RubyThroat: The Hummingbird Project" is an international cross-disciplinary initiative that uses Ruby-throated Hummingbirds (Archilochus colubris) as a hook to excite K-12 students (and adults) about science learning. In 2002, Operation RubyThroat affiliated with The GLOBE Program as the first GLOBE protocol that involves animal behavior. Through Operation RubyThroat, students make observations about hummingbird phenology, behavior, and ecology and correlate their data against traditional GLOBE observations of atmosphere, climate, land cover, soils, hydrology, and phenology. Although Ruby-throated Hummingbirds (RTHUs) breed throughout the eastern half of the United States and southern Canada and may be the most common and most widely distributed of all 338 hummingbird species, little is known about how abiotic environmental factors affect their migration, nesting activities, and everyday behavior. Operation RubyThroat participants in the U.S. and Canada log early arrival dates of RTHUs during spring migration, note their presence throughout the breeding season, and report the last date RTHUs are seen in autumn. Conversely, participants in Mexico and all seven Central American countries (the region in which RTHUs spend their non-breeding months) watch for early arrivals in fall and late departures in spring. Participants also attempt to estimate numbers of RTHUs in local populations by counting the number of visits hummingbirds make to feeders and/or flowers in a 45-minute time block. Optional activities include observations of RTHU nesting behaviors and determining RTHU preferences for various species of native and exotic nectar sources. Participating schools are encouraged to establish Schoolyard Hummingbird Habitats in which to make their observations, but data may be collected in backyards or at local parks, nature centers, botanical gardens, and other sites where RTHUs occur. Adults not affiliated with K-12 schools are invited to become certified in

THE REPRESENTATION OF EGYPTIAN PEOPLE’S VOICE IN THE JAKARTA GLOBE NEWS PHOTOGRAPHS

Directory of Open Access Journals (Sweden)

Fini Fitriani

2012-07-01

Full Text Available Abstract: As a product of mass media, news photograph is an image which provides the viewers with a valuable source of information and news story. All events captured in photographs turn into a news photo. Besides covering the news with fact, news photographs do not only have surface meanings, but also deeper meanings to be interpreted by each viewer. The phenomenon of demonstration, particularly the massive demonstration in Egypt in 2011, offers a good chance to discover how visual messages have been presented to guide interpretation of foreign news events. Principally, demonstration is an expression of the people’s voices, and thus, their voices are related closely with their demands, grievances and wishes related to the new government. Here, the photographs are able to portray and reflect the people’s voices through the compositions and contents (meanings involved in the photos. This study is aimed at discovering the portrayal of the voice of the people (the protesters in the news photographs of the Indonesian online newspaper, The Jakarta Globe. The data consist of 15 news photographs taken from The Jakarta Globe online newspaper published in January – October 2011. The study employs qualitative method framed with semiotic analysis using Roland Barthes’ theory of orders of signification and photographic message. The results of the study show that The Jakarta Globe visually constructs this event (demonstration by focusing on the human action (the protesters. Thus, the voice of the people is portrayed in the photo subjects (the protesters and the included objects of the photo. Meanwhile, the technical aspects of the photos play a meaningful role in emerging the portrayal of the people’s voice. There are four voices revealed by the people in the 15 photographs, namely the voice of freedom, the voice of peace, the voice of justice and the voice of human rights. The photo text including headlines and captions also interact with

Streamlining Education System Through Waqf Enlargement

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Imam Bahroni

2016-06-01

Full Text Available This paper is aimed at discussing the development of education systembased on the Waqf Empowerment. It is an experience of Gontor ModernIntegrated Islamic Institution to maintain its existence through the activitiesof Waqf Enlargement. The spirit of self-reliance which has been implementedby Gontor through various economic enterprise activities inside the campus isthe total processes of educational activities, carried out by students andteachers themselves. They act as the subjects and objects of the education atthe same time. They teach themselves through various activities, creativitiesand social interaction for their character and personality building. Thislearning process is purposely undertaken in Gontor, because the basicprinciple of this system is to actualize the community orientation throughwhich the students in the campus guided and prepared to have a spirit ofself reliance. So when they back to the society to undertake the real life theyconfidently take their role to develop their society for the sake of Allah andunity of muslim ummah.

Biogas i økologisk jordbrug

DEFF Research Database (Denmark)

Østergård, Hanne

2011-01-01

Klumme: Hvilke faktorer har størst betydning for udbredelse af biogas-teknologien? Offentlige tilskud er svaret fra en rundspørge.......Klumme: Hvilke faktorer har størst betydning for udbredelse af biogas-teknologien? Offentlige tilskud er svaret fra en rundspørge....

An enlarged superfluid model of atomic nucleus

International Nuclear Information System (INIS)

Dumitrescu, O.; Horoi, M.

1989-01-01

The well known superfluid model (or quasiparticle phonon nuclear model (QPNM)) of atomic nucleus is enlarged by including an adequate four-nucleon effective interaction in addition to the pairing and long-range effective residual interactions. New experimental data can be explained without affecting those observables already described by the QPNM and in addition new features can be enumerated: 1) superfluidities of the neutron and proton systems may be generated by one another; 2) the phase structure is enriched by a new superfluid phase dominated by alpha-type correlations (ATC) and 3) superfluid isomers and their bands of elementary excitations are predicted. Unusual large two-nucleon and alpha transfer reactions cross sections as well as some unusual large alpha decay widths can be explained. (author). 46 refs, 3 figs, 2 tabs

Customization of the voice prosthesis to prevent leakage from the enlarged tracheoesophageal puncture: results of a prospective trial.

Science.gov (United States)

Lewin, Jan S; Hutcheson, Katherine A; Barringer, Denise A; Croegaert, Lindsay E; Lisec, Asher; Chambers, Mark S

2012-08-01

Customization of the tracheoesophageal (TE) voice prosthesis (VP) is often preferred over surgical closure to prevent aspiration around the VP in laryngectomized patients with an enlarged tracheoesophageal puncture (TEP), but it has not been thoroughly evaluated. Single-institution prospective trial. A prospective trial was conducted to evaluate the effectiveness of a customized VP with the addition of an enlarged tracheal and/or esophageal collar in patients with leakage around an enlarged TEP. Absence of leakage around the VP after placement defined immediate effectiveness. Long-term success was defined by the prevention of adverse events related to leakage during the study period. Events that defined failure included: permanent gastrostomy dependence, aspiration pneumonia, and/or surgical TEP closure. Twenty-one patients with enlarged TEP were enrolled (2003-2006). Insertion of a customized VP was unsuccessful in one patient; 145 customizations were performed in the remaining 20 patients (median, 3.5 customizations) during the trial period. Of the customizations, 77% (112/145) prevented leakage immediately after VP insertion. The most common adverse event was dislodgement of the prosthesis (11%) or the collar alone (7%) in 18% (26/145) of customized VP placements. Six patients who died of disease were not evaluable for long-term outcomes. Long-term success was achieved in 80% (12/15) of evaluable patients who avoided permanent gastrostomy, aspiration pneumonia, and surgical TEP closure. Prosthetic customization offers an effective method to prevent leakage around the VP in many patients with an enlarged TEP, thereby preserving TE voice while avoiding surgical closure in this high-risk population. Copyright © 2012 The American Laryngological, Rhinological, and Otological Society, Inc.

Enriching science, practice, and policy relevant to school psychology around the globe.

Science.gov (United States)

Jimerson, Shane R

2016-03-01

This editorial provides a brief synthesis of the past, present, and future of School Psychology Quarterly, highlighting important contributions as an international resource to enrich, invigorate, enhance, and advance science, practice, and policy relevant to school psychology around the globe. Information herein highlights (a) the value of high quality and timely reviews, (b) publishing manuscripts that address a breadth of important topics relevant to school psychology, and (c) the structure and contributions of the special topic sections featured in School Psychology Quarterly. (c) 2016 APA, all rights reserved).

Reflujo gastroesofágico en pediatría

OpenAIRE

GUEVARA P, GLADYS; TOLEDO C, MARCELA

2011-01-01

El reflujo gastroesofagico (RGE) es el paso del contenido gástrico hacia el esófago con o sin vómitos o regurgitación. El RGE es un proceso normal fisiológico que ocurre en el 50% de los lactantes, resolviéndose espontáneamente a los 12 a 14 meses de edad. Cuando este contenido retrógrado gástrico alcanza al esófago y produce síntomas molestos o complicaciones se produce la enfermedad por RGE o ERGE. Los episodios de reflujo se producen principalmente por relajaciones transitorias del esfínte...

Gingival enlargment treatment on 11 and 21 teeth: A case report

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Umi Ghoni Tjiptoningsih

2016-06-01

Full Text Available The main problem of gingival enlargement in the interdental papillae is thickening of gingival contour, rounde and uncomfort feeling, that must be needed immediate in order to be optimal appearance and functionale. Fibrosis gingival enlargement  wont be healed  with plaque control only, but must be require a surgery treatment such as gingivectomy and gingivoplasty. A 24-year-old woman  came into periodontia clinic complaining a hard swelling at anterior maxillary gingiva at 11-21. Plaque index 52%. Gingival pocket depth at tooth 11 is labial (mesial: 4, medial:1, distal:3. Palatal (mesial:3, medial:2, distal:1 and Tooth 21 is labial (mesial:4, medial:1, distal:1, palatal (mesial:3, medial:1, distal:1. Treatment planning done by gingivectomy and gingivoplasty. The aim of the treatment is to eliminating the gingival pocket and physiologic gingival recontouring that can be help to prevent the recurrence of the disease. We must be considered in gingivectomy and gingivoplasty surgery is to minimize disposal the gingival to maintain the aesthetic, adequate access to the bone defect in order to good correction, minimized the bleeding and discomfort after surgery.

Projecting the effectiveness of RotaTeq® against rotavirus-related hospitalisations in Brazil

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Antoine Chaouki El Khoury

2011-08-01

Full Text Available RotaTeq® (Merck & Company, Inc, Whitehouse Station, NJ, USA is an oral pentavalent rotavirus vaccine (RV5 that has shown high and consistent efficacy in preventing rotavirus gastroenteritis (RGE in randomised clinical trials previously conducted in industrialised countries with high medical care resources. To date, the efficacy and effectiveness data for RV5 are available in some Latin American countries, but not Brazil. In this analysis, we projected the effectiveness of RV5 in terms of the percentage reduction in RGE-related hospitalisations among children less than five years of age in four regions of Brazil, using a previously validated mathematical model. The model inputs included hospital-based rotavirus surveillance data from Goiânia, Porto Alegre, Salvador and São Paulo from 2005-2006, which provided the proportions of rotavirus attributable to serotypes G1, G2, G3, G4 and G9, and published rotavirus serotype-specific efficacy from the Rotavirus Efficacy and Safety Trial. The model projected an overall percentage reduction of 93% in RGE-related hospitalisations, with an estimated annual reduction in RGE-related hospitalisations between 42,991-77,383 in the four combined regions of Brazil. These results suggest that RV5 could substantially prevent RGE-related hospitalisations in Brazil.

A retrospective review of bone tunnel enlargement after anterior cruciate ligament reconstruction with hamstring tendons fixed with a metal round cannulated interference screw in the femur.

Science.gov (United States)

Kobayashi, Masahiko; Nakagawa, Yasuaki; Suzuki, Takashi; Okudaira, Shuzo; Nakamura, Takashi

2006-10-01

To assess bone tunnel enlargement after anterior cruciate ligament (ACL) reconstruction with the use of hamstring tendons fixed with a round cannulated interference (RCI) screw in the femur. A consecutive series of 30 ACL reconstructions performed with hamstring tendons fixed with an RCI screw in the femur and with staples via Leeds-Keio ligament in the tibia was retrospectively reviewed. The clinical outcome was evaluated through the Lysholm score. Anterior instability was tested by Telos-SE (Telos Japan, Tokyo, Japan) measurement. The location and angle of each femoral and tibial tunnel were measured with the use of plain radiographs, and bone tunnel enlargement greater than 2 mm detected any time 3, 6, 12, and 24 months postoperatively was defined as positive. Each factor (location and angle of the tunnels, sex, affected side, age, Lysholm score, and Telos-SE measurement) was compared between enlarged and nonenlarged groups. Positive enlargement of the bone tunnel (>2.0 mm) was observed in 36.7% (11 of 30) on the femoral side and 33.3% (10 of 30) on the tibial side, and in 6 knees of both sides. Half of patients (15 of 30) had an enlarged tunnel on the femoral or the tibial side until 1 year postoperatively. In most cases, enlargement reached maximum at 6 months postoperatively. Female patients tended to have an enlarged tunnel, especially on the femoral side (P < .05). Tunnel enlargement was not correlated with location and angle of the tunnels. Moreover, no difference was found in Lysholm score and Telos-SE measurement between enlarged and nonenlarged groups, although the nonenlarged group tended to exhibit higher Lysholm score and lesser instability. Bone tunnel enlargement of the femoral or tibial side was observed in half of patients (6 in both sides, 5 only in the femur, and 4 only in the tibia) after ACL reconstruction was performed with a hamstring tendon fixed with an RCI screw. Female patients had a greater chance for enlargement of the femoral tunnel

Virtual Globes: Serving Science and Society

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Salman Qureshi

2012-08-01

Full Text Available Virtual Globes reached the mass market in 2005. They created multi-million dollar businesses in a very short time by providing novel ways to explore data geographically. We use the term “Virtual Globes” as the common denominator for technologies offering capabilities to annotate, edit and publish geographic information to a world-wide audience and to visualize information provided by the public and private sectors, as well as by citizens who volunteer new data. Unfortunately, but not surprising for a new trend or paradigm, overlapping terms such as “Virtual Globes”, “Digital Earth”, “Geospatial Web”, “Geoportal” or software specific terms are used heterogeneously. We analyze the terminologies and trends in scientific publications and ask whether these developments serve science and society. While usage can be answered quantitatively, the authors reason from the literature studied that these developments serve to educate the masses and may help to democratize geographic information by extending the producer base. We believe that we can contribute to a better distinction between software centered terms and the generic concept as such. The power of the visual, coupled with the potential of spatial analysis and modeling for public and private purposes raises new issues of reliability, standards, privacy and best practice. This is increasingly addressed in scientific literature but the required body of knowledge is still in its infancy.

Enlarging the underground hydroelectric plant at Villarino, Spain

Energy Technology Data Exchange (ETDEWEB)

Oriard, L.L.

1997-05-01

Near the village of Villarino de los Aires, in the province of Salamanca, Spain, was an existing underground hydroelectric power plant. A major enlargement was undertaken to increase the electrical generating capacity, under a contract awarded to a joint venture of Dragados y Construcciones, S. A. (Spain), Entrecanales y Tavora, S. A. (Spain), and S.A. Conrad Zschokke (Switzerland). The enlargement required the excavation of a large and complex underground system of tunnels, shafts and chambers adjacent to existing facilities and interconnected with these facilities. The existing machine hall and transformer chamber were both extended, requiring the blasting of the existing end walls. The drilling, blasting and excavating of the underground system had to be done without damage to existing underground chambers and tunnels, or any of the existing structures, equipment or instrumentation facilities, often within just a few feet of the blasting. This required careful control of vibrations, airblast overpressures and dust. Because the only available non-electric detonating systems were found to be unreliable and unsafe, electric systems would be preferred if they could be used in a safe manner at this site. High electrical potentials existed at the site, and the facilities could not be shut down. Electrical fields were studied carefully, both in the underground environment and above the ground surface. Based on these results, it was concluded that electric detonators could be used if special blasting procedures were developed and followed. In accord with contracting practices of this Spanish agency, the contract was not awarded to the lowest bidder, but to the bidder who demonstrated the best understanding of the project and who presented the best technical proposal for conducting the work to a conclusion that would be satisfactory to the owner. The development of the technical proposal was a two-month effort for a technical group and support staff, prepared in Madrid.

Hearing loss in enlarged vestibular aqueduct and incomplete partition type II.

Science.gov (United States)

Ahadizadeh, Emily; Ascha, Mustafa; Manzoor, Nauman; Gupta, Amit; Semaan, Maroun; Megerian, Cliff; Otteson, Todd

The purpose of this work is to identify the role of incomplete partition type II on hearing loss among patients with enlarged vestibular aqueduct (EVA). EVA is a common congenital inner ear malformation among children with hearing loss, where vestibular aqueduct morphology in this population has been shown to correlate to hearing loss. However, the impact of incomplete partition between cochlear turns on hearing loss has not been, despite meaningful implications for EVA pathophysiology. A retrospective review of radiology reports for patients who had computed tomography (CT) scans with diagnoses of hearing loss at a tertiary medical center between January 2000 and June 2016 were screened for EVA. CT scans of the internal auditory canal (IAC) for those patients with EVA were examined for evidence of incomplete partition type II (IP-II), measurements of midpoint width and operculum width a second time, and patients meeting Cincinnati criteria for EVA selected for analysis. Statistical analysis including chi-square, Wilcoxon rank-sum, and t-tests were used to identify differences in outcomes and clinical predictors, as appropriate for the distribution of the data. Linear mixed models of hearing test results for all available tests were constructed, both univariable and adjusting for vestibular aqueduct morphometric features, with ear-specific intercepts and slopes over time. There were no statistically significant differences in any hearing test results or vestibular aqueduct midpoint and operculum widths. Linear mixed models, both univariable and those adjusting for midpoint and operculum widths, did not indicate a statistically significant effect of incomplete partition type II on hearing test results. Hearing loss due to enlarged vestibular aqueduct does not appear to be affected by the presence of incomplete partition type II. Our results suggest that the pathophysiological processes underlying hearing loss in enlarged vestibular aqueduct may not be a result of

An enlarged parietal foramen in the late archaic Xujiayao 11 neurocranium from Northern China, and rare anomalies among Pleistocene Homo.

Science.gov (United States)

Wu, Xiu-Jie; Xing, Song; Trinkaus, Erik

2013-01-01

We report here a neurocranial abnormality previously undescribed in Pleistocene human fossils, an enlarged parietal foramen (EPF) in the early Late Pleistocene Xujiayao 11 parietal bones from the Xujiayao (Houjiayao) site, northern China. Xujiayao 11 is a pair of partial posteromedial parietal bones from an adult. It exhibits thick cranial vault bones, arachnoid granulations, a deviated posterior sagittal suture, and a unilateral (right) parietal lacuna with a posteriorly-directed and enlarged endocranial vascular sulcus. Differential diagnosis indicates that the perforation is a congenital defect, an enlarged parietal foramen, commonly associated with cerebral venous and cranial vault anomalies. It was not lethal given the individual's age-at-death, but it may have been associated with secondary neurological deficiencies. The fossil constitutes the oldest evidence in human evolution of this very rare condition (a single enlarged parietal foramen). In combination with developmental and degenerative abnormalities in other Pleistocene human remains, it suggests demographic and survival patterns among Pleistocene Homo that led to an elevated frequency of conditions unknown or rare among recent humans.

An enlarged parietal foramen in the late archaic Xujiayao 11 neurocranium from Northern China, and rare anomalies among Pleistocene Homo.

Directory of Open Access Journals (Sweden)

Xiu-Jie Wu

Full Text Available We report here a neurocranial abnormality previously undescribed in Pleistocene human fossils, an enlarged parietal foramen (EPF in the early Late Pleistocene Xujiayao 11 parietal bones from the Xujiayao (Houjiayao site, northern China. Xujiayao 11 is a pair of partial posteromedial parietal bones from an adult. It exhibits thick cranial vault bones, arachnoid granulations, a deviated posterior sagittal suture, and a unilateral (right parietal lacuna with a posteriorly-directed and enlarged endocranial vascular sulcus. Differential diagnosis indicates that the perforation is a congenital defect, an enlarged parietal foramen, commonly associated with cerebral venous and cranial vault anomalies. It was not lethal given the individual's age-at-death, but it may have been associated with secondary neurological deficiencies. The fossil constitutes the oldest evidence in human evolution of this very rare condition (a single enlarged parietal foramen. In combination with developmental and degenerative abnormalities in other Pleistocene human remains, it suggests demographic and survival patterns among Pleistocene Homo that led to an elevated frequency of conditions unknown or rare among recent humans.

Efficacy of the fractional photothermolysis system with dynamic operating mode on acne scars and enlarged facial pores.

Science.gov (United States)

Cho, Sung Bin; Lee, Ju Hee; Choi, Moon Jung; Lee, Kyu-Yeop; Oh, Sang Ho

2009-01-01

Current treatments for acne scars and enlarged facial pores have shown limited efficacy. To evaluate the efficacy and safety of the fractional photothermolysis system (FPS) with dynamic operating mode on acne scars and enlarged pores. Twelve patients with mild to moderate atrophic acne scars and enlarged pores were included in this study. Three sessions of FPS treatment were performed for acne scars and facial pores monthly. Two blinded dermatologists who compared before and after photos based on a quartile grading scale conducted objective clinical assessments of acne scar- and facial pore-treated areas. We took a biopsy immediately after one treatment with the laser from one of the authors to assess the histologic effects of the laser on facial pores. Follow-up results at 4 months after the last treatment revealed that, of the 12 patients, for acne scars, five demonstrated clinical improvements of 51% to 75% and three demonstrated improvements of 76% to 100%, and for facial pores, five demonstrated moderate clinical improvements of 26% to 50% and three demonstrated improvements of 76% to 100%. Side effects, including pain, post-treatment erythema, and edema, were resolved within 1 week. We suggest that the FPS may provide a new treatment algorithm in some cases with acne scars and enlarged pores. Considering the lack of placebo-controlled, split-face design of our study, optimized, prospective studies should be conducted to fully assess the efficacy of FPS with dynamic operating mode.

Kleptochloroplast Enlargement, Karyoklepty and the Distribution of the Cryptomonad Nucleus in Nusuttodinium (= Gymnodinium) aeruginosum (Dinophyceae).

Science.gov (United States)

Onuma, Ryo; Horiguchi, Takeo

2015-05-01

The unarmoured freshwater dinoflagellate Nusuttodinium (= Gymnodinium) aeruginosum retains a cryptomonad-derived kleptochloroplast and nucleus, the former of which fills the bulk of its cell volume. The paucity of studies following morphological changes to the kleptochloroplast with time make it unclear how the kleptochloroplast enlarges and why the cell ultimately loses the cryptomonad nucleus. We observed, both at the light and electron microscope level, morphological changes to the kleptochloroplast incurred by the enlargement process under culture conditions. The distribution of the cryptomonad nucleus after host cell division was also investigated. The volume of the kleptochloroplast increased more than 20-fold, within 120h of ingestion of the cryptomonad. Host cell division was not preceded by cryptomonad karyokinesis so that only one of the daughter cells inherited a cryptomonad nucleus. The fate of all daughter cells originating from a single cell through five generations was closely monitored, and this observation revealed that the cell that inherited the cryptomonad nucleus consistently possessed the largest kleptochloroplast for that generation. Therefore, this study suggests that some important cryptomonad nucleus division mechanism is lost during ingestion process, and that the cryptomonad nucleus carries important information for the enlargement of the kleptochloroplast. Copyright © 2015 Elsevier GmbH. All rights reserved.

Spontaneous breast enlargement following liposuction of the abdominal wall : Does a link exist?

NARCIS (Netherlands)

van der Lei, Berend; Halbesma, Gert-Jan; van Nieuwenhoven, Christianne A.; van Wingerden, Jan J.

2007-01-01

Background: A retrospective study was undertaken to determine the specific incidence of breast enlargement following liposuction of the abdomen (alone or in combination with the flanks), and to compare its effect with a control group of patients who had undergone abdominoplasty only and, where

Spontaneous breast enlargement following liposuction of the abdominal wall: does a link exist?

NARCIS (Netherlands)

van der Lei, Berend; Halbesma, Gert-Jan; van Nieuwenhoven, Christianne A.; van Wingerden, Jan J.

2007-01-01

A retrospective study was undertaken to determine the specific incidence of breast enlargement following liposuction of the abdomen (alone or in combination with the flanks), and to compare its effect with a control group of patients who had undergone abdominoplasty only and, where possible,

An introduction to environmental law. 2. enlarged ed.

International Nuclear Information System (INIS)

Schmidt, R.; Mueller, H.

1989-01-01

The author outlines the environmental law in the Federal Republic of Germany and surveys the main legal regulations in the field of environmental protection. Inter alia he deals with problems of installations subject to permission and with legal questions of transfrontier environmental pollution. This second edition brings up to date or enlarges the first by information and facts concerning in particular the deficits in enforcement, informal acts of the administration, the protection of animals and endangered species of wild fauna and flora, the environmental impact statement, liability for environmental pollution, the problems involved in the management of waste found at abandoned industrial sites or dumps, radiological protection issues, and environmental protection provided by the EEC Treaty. (orig./HP) [de

Hepatic Epithelioid Hemangioendothelioma Presenting as an Enlarging Vascular Lesion within the Spleen

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Juliet A. Emamaullee

2018-01-01

Full Text Available Epithelioid hemangioendothelioma (EHE is a rare vascular neoplasm with variable malignant potential that most often presents within the liver. Many patients present with bilobar or extrahepatic disease, and the current treatment paradigm involves liver transplantation, with favorable long term results. Up to 25% of patients are diagnosed incidentally following imaging for other indications, and confirmation of diagnosis requires histologic analysis, as there are no classical imaging features to distinguish hepatic EHE (HEHE from other solid hepatic lesions. Here we describe a case of microscopic HEHE that was diagnosed following splenectomy for an enlarging vascular tumor within the spleen. Due to the unexpected diagnosis of EHE within the spleen and coexisting but stable appearing liver hemangiomata, a left hepatic lobectomy was performed. Explant histology revealed benign hemangiomata and diffuse, microscopic HEHE. The patient ultimately underwent liver transplantation. HEHE can be a challenging diagnosis, and this case emphasizes that any enlarging vascular lesion, even within the spleen, should prompt a high index of suspicion for HEHE in the setting of known hemangiomata.

Examining the Structure of Vocational Interests in Turkey in the Context of the Personal Globe Model

Science.gov (United States)

Vardarli, Bade; Özyürek, Ragip; Wilkins-Yel, Kerrie G.; Tracey, Terence J. G.

2017-01-01

The structural validity of the Personal Globe Inventory-Short (PGI-S: Tracey in J Vocat Behavi 76:1-15, 2010) was examined in a Turkish sample of high school and university students. The PGI-S measures eight basic interest scales, Holland's ("Making vocational choice," Prentice-Hall, Englewood Cliffs, 1997) six types, Prediger's ("J…

Coil embolization of an enlarging fusiform myxomatous cerebral aneurysm

Directory of Open Access Journals (Sweden)

Frances Lazarow, MD

2018-04-01

Full Text Available Myxomatous cerebral aneurysms are rare sequelae of cardiac atrial myxoma. These aneurysms are generally fusiform, multiple, and distal. Pathogenesis and evolution of these aneurysms is still debated. There are currently no guidelines on the management of aneurysms secondary to atrial myxoma. We present a case of a 52-year-old man with multiple fusiform aneurysms 3 years after resection of a left atrial myxoma. One of these aneurysms was followed with cerebral angiography and showed substantial interval enlargement. This aneurysm was subsequently embolized. All aneurysms were stable 6 months post-embolization. Keywords: Myxomatous aneurysm, Fusiform, Coil embolization

EU Enlargement between Economic and Political Criteria

Directory of Open Access Journals (Sweden)

Romeo-Victor Ionescu

2013-05-01

Full Text Available The paper answers at two important questions: Is the EU able to support new adhering processes? and Is the Euro area able to enlarge in 2014? The comparative analysis in the paper covers four economic competitors: EU, USA, China and Japan, and is based on GDP growth rate, unemployment and inflation rates. The second part of the paper deals with an economic forecast during 2015-2016, focused on EU27, Euro area, Croatia and Latvia, in order to discuss the effects of the adhering to EU and Euro area. The results of the two-level analysis are supported by pertinent diagrams and annexes. The analysis uses a neutral statistical database – Eurostat – and dedicated forecast software. The main conclusion of the paper is that the adhering processes from 2013 and 2014 are based on economic and political criteria.

Gene-Environment Correlation Underlying the Association between Parental Negativity and Adolescent Externalizing Problems

Science.gov (United States)

Marceau, Kristine; Horwitz, Briana N.; Narusyte, Jurgita; Ganiban, Jody M.; Spotts, Erica L.; Reiss, David; Neiderhiser, Jenae M.

2013-01-01

Studies of adolescent or parent-based twins suggest that gene-environment correlation (rGE) is an important mechanism underlying parent-adolescent relationships. However, information on how parents' and children's genes and environments influence correlated parent "and" child behaviors is needed to distinguish types of rGE. The present…

Prognostic factors for open globe injuries and correlation of Ocular Trauma Score at a tertiary referral eye care centre in Singapore

Directory of Open Access Journals (Sweden)

Rupesh Agrawal

2013-01-01

Full Text Available Objective: To evaluate the factors influencing final vision outcome after surgical repair of open globe injuries and to correlate the Ocular trauma score. Materials and Methods: Retrospective case analysis of patients with open globe injuries at a tertiary referral eye care centre in Singapore was performed. Pre-operative factors affecting final vision outcome in patients with open globe injury and correlation of ocular trauma score in our study with international ocular trauma scoring system was performed. Results: Case records of 172 eyes with open globe injury were analyzed. Mean age was 36. 67 years. Mean follow up was 12.26 m. Males were pre-dominantly affected. Initial visual acuity was ≥20/40, 20/50 < 20/200, 20/200- CF, HM- PL and NLP in 24 (14%, 39 (22.7%, 16 (9.3%, 66 (38.4% and 27 (15.7% eyes respectively. Final visual acuity was ≤20/40, 20/50 < 20/200, 20/200- 1/200, HM- PL and NLP in 76 (44.2%, 28 (16.3%, 11 (6.4%, 30 (17.4% and 27 (15.7% eyes respectively. Ocular trauma score in our study correlates with international ocular trauma scoring system. Conclusion: The present study showed pre-operative variables such as mode of injury, pre-operative visual acuity, traumatic cataract, hyphaema, relative afferent papillary defect, vitreous lossand vitreous hemorrhage to be adversely affecting the final vision outcome. Our study showed a good synchrony with international ocular trauma score (OTS and based on this study we were able to validate application of OTS in Singapore population. Recognizing these factors can help the surgeon in evidence based counseling.

The Palm-Heart Diameter: A Prospective Simple Screening Tool for Identifying Heart Enlargement

Directory of Open Access Journals (Sweden)

Adegbenro Omotuyi John Fakoya

2017-11-01

CONCLUSION: This study establishes the correlation between the palm and heart diameters. Since the heart tissue and the upper limb share a similar embryonic origin, being the mesoderm, this study prospects the fact that heart enlargement could be preliminarily identified by measuring the size of the hand.

[Enlargement in managment of lumbar spinal stenosis].

Science.gov (United States)

Steib, J P; Averous, C; Brinckert, D; Lang, G

1996-05-01

Lumbar stenosis has been well discussed recently, especially at the 64th French Orthopaedic Society (SOFCOT: July 1989). The results of different surgical treatments were considered as good, but the indications for surgical treatment were not clear cut. Laminectomy is not the only treatment of spinal stenosis. Laminectomy is an approach with its own rate of complications (dural tear, fibrosis, instability... ).Eight years ago, J. Sénégas described what he called the "recalibrage" (enlargement). His feeling was that, in the spinal canal, we can find two different AP diameters. The first one is a fixed constitutional AP diameter (FCAPD) at the cephalic part of the lamina. The second one is a mobile constitutional AP diameter (MCAPD) marked by the disc and the ligamentum flavum. This diameter is maximal in flexion, minimal in extension. The nerve root proceeds through the lateral part of the canal: first above, between the disc and the superior articular process, then below, in the lateral recess bordered by the pedicle, the vertebral body and the posterior articulation. With the degenerative change the disc space becomes shorter, the superior articular process is worn out with osteophytes. These degenerative events are complicated by inter vertebral instability increasing the stenosis. The idea of the "recalibrage" is to remove only the upper part of the lamina with the ligamentum flavum and to cut the hypertrophied anterior part of the articular process from inside. If needed the disc and other osteophytes are removed. The surgery is finished with a ligamentoplasty reducing the flexion and preventing the extension by a posterior wedge.Our experience in spine surgery especially in scoliosis surgery, showed us that it was possible to cure a radicular compression without opening the canal. The compression is then lifted by the 3D reduction and restoration of an anatomy as normal as possible. Lumbar stenosis is the consequence of a degenerative process. Indeed, hip

In vitro micropropagation and mycorrhizal treatment influences the polyphenols content profile of globe artichoke under field conditions.

Science.gov (United States)

Pandino, Gaetano; Lombardo, Sara; Antonino, Lo Monaco; Ruta, Claudia; Mauromicale, Giovanni

2017-09-01

The commercial importance of plant tissue culture has grown in recent years, reflecting its application to vegetative propagation, disease elimination, plant improvement and the production of polyphenols. The level of polyphenols present in plant tissue is influenced by crop genotype, the growing environment, the crop management regime and the post-harvest processing practice. Globe artichoke is a significant component of the Mediterranean Basin agricultural economy, and is rich in polyphenols (phenolic acids and flavones). Most commercially grown plants are derived via vegetative propagation, with its attendant risk of pathogen build-up. Here, a comparison was drawn between the polyphenol profiles of conventionally propagated and micropropagated/mycorrhized globe artichoke plants. Micropropagation/mycorrhization appeared to deliver a higher content of caffeoylquinic acids. The accumulation of these compounds, along with luteolin and its derivatives, was not season-dependent. Luteolin aglycone was accumulated preferentially in the conventionally propagated plants. Overall, it appeared that micropropagation/mycorrhization enhanced the accumulation of polyphenols. Copyright © 2017. Published by Elsevier Ltd.

Improving the Effect and Efficiency of FMD Control by Enlarging Protection or Surveillance Zones

DEFF Research Database (Denmark)

Hisham Beshara Halasa, Tariq; Toft, Nils; Boklund, Anette

2015-01-01

An epidemic of foot-and-mouth disease (FMD) in a FMD-free country with large exports of livestock and livestock products would result in profound economic damage. This could be reduced by rapid and efficient control of the disease spread. The objectives of this study were to estimate the economic...... impact of a hypothetical FMD outbreak in Denmark based on changes to the economic assumptions of the model, and to investigate whether the control of an FMD epidemic can be improved by combining the enlargement of protection or surveillance zones with pre-emptive depopulation or emergency vaccination....... The stochastic spatial simulation model DTU-DADS was used to simulate the spread of FMD in Denmark. The control strategies were the basic EU and Danish strategy, pre-emptive depopulation, suppressive or protective vaccination, enlarging protection or surveillance zones, and a combination of pre...

Acinar cell carcinoma of the pancreas presenting as diffuse pancreatic enlargement: Two case reports and literature review.

Science.gov (United States)

Luo, Yaping; Hu, Guilan; Ma, Yanru; Guo, Ning; Li, Fang

2017-09-01

Pancreatic acinar cell carcinoma (ACC) is a rare malignant tumor of exocrine pancreas. It is typically a well-marginated large solid mass arising in a certain aspect of the pancreas. Diffuse involvement of ACC in the pancreas is very rare, and may simulate pancreatitis in radiological findings. We report 2 cases of ACC presenting as diffuse enlargement of the pancreas due to tumor involvement without formation of a distinct mass. The patients consisted of a 41-year-old man with weight loss and a 77-year-old man who was asymptomatic. Computed tomography (CT) and 18F-fluorodeoxyglucose (FDG) positron emission tomography (PET)/CT showed diffuse enlargement of the pancreas forming a sausage-like shape with homogenously increased FDG activity. Endoscopic ultrasound (EUS)-guided fine needle aspiration (FNA) biopsy of the pancreatic lesion was performed. Histopathology results from the pancreas confirmed the diagnosis of pancreatic ACC. Because diffuse enlargement of the pancreas is a common imaging feature of pancreatitis, recognition of this rare morphologic pattern of ACC is important for radiological diagnosis of this tumor.

Emotional stimuli-provoked seizures potentially misdiagnosed as psychogenic non-epileptic attacks: A case of temporal lobe epilepsy with amygdala enlargement

Directory of Open Access Journals (Sweden)

Hidetaka Tamune

Full Text Available The association between emotional stimuli and temporal lobe epilepsy (TLE is largely unknown. Here, we report the case of a depressed, 50-year-old female complaining of episodes of a “spaced out” experience precipitated by emotional stimuli. Psychogenic non-epileptic attacks were suspected. However, video-EEG coupled with emotional stimuli-provoked procedures and MRI findings of amygdala enlargement, led to the diagnosis of left TLE. Accurate diagnosis and explanation improved her subjective depression and seizure frequency. This case demonstrated that emotional stimuli can provoke seizures in TLE and suggested the involvement of the enlarged amygdala and the modulation of emotion-related neural circuits. Keywords: Video-EEG, Psychogenic non-epileptic attacks, Temporal lobe epilepsy, Amygdala enlargement, Reflex seizure, Provoked seizure

Postoperative pain after foraminal enlargement in anterior teeth with necrosis and apical periodontitis: a prospective and randomized clinical trial.

Science.gov (United States)

Silva, Emmanuel João Nogueira Leal; Menaged, Karyne; Ajuz, Natasha; Monteiro, Maria Rachel Figueiredo Penalva; Coutinho-Filho, Tauby de Souza

2013-02-01

The aim of this randomized, controlled, prospective clinical study was to determine if foraminal enlargement instrumentation during endodontic treatment is associated with more postoperative pain compared with standard nonenlargement instrumentation. Forty volunteers with a single root canal were diagnosed with asymptomatic necrosis with apical periodontitis and randomized into 2 experimental groups (ie, the control group and the foraminal enlargement group). Endodontic treatment was performed in a single visit, and volunteers were instructed to record pain intensity (ie, none, slight, moderate, and severe). Scores from 1 to 4 were attributed to each kind of pain after 12, 24, and 48 hours. The Kolmogorov-Smirnov and Student's t tests were used to determine significant differences at P .05, Student's t test). Postoperative pain showed no statistically significant difference between the groups at any observation period (P > .05). Also, no significant difference was observed in the mean number of analgesic tablets used between the groups (P > .05). The foraminal enlargement and nonenlargement techniques resulted in the same postoperative pain and necessity for analgesic medication. This may suggest that the use of foraminal enlargement should be performed for endodontic treatment previsibility without increasing postoperative pain. Copyright © 2013 American Association of Endodontists. Published by Elsevier Inc. All rights reserved.

Diagnostic criteria for enlarged vestibular aqueduct (EVA) on CT of the temporal bones. Borderline cases of EVA

International Nuclear Information System (INIS)

Matsumoto, Mariko; Hoshino, Tomoyuki; Kikura, Mikino; Kikawada, Keiko; Kikawada, Toru

2005-01-01

The objective of this study was to examine measurements of the vestibular aqueduct on axial CT figures and to examine the cases with borderline EVA. The width of the vestibular aqueduct was measured in two places, the midpoint of the duct and the external aperture in the posterior cranial fossa. Criteria was as follow: Enlargement; ≥1.5 mm at the midpoint, ≥2 mm at the aperture, Borderline; 1-1.4 mm at the midpoint, 1.5-1.9 mm at the aperture. Three hundred forty-five cases with CT scans of the temporal bones taken during July 2003 to June 2004 in the secondary ENT referral center. Those patients include sensorinearal, mixed or conductive deafness, vertigo, ear infections and other ear diseases. Enlarged vestibular aqueduct was found in 10 ears with sensorineural deafness (SD) and 2 ears without SD. Borderline measurements were found in 19 ears with SD and 33 ears without SD. The enlarged midpoint measurement was not seen in the cases without SD. More than 1.5 mm of the definition for the enlargement at the midpoint of the vestibular aqueduct seemed to be appropriate in the clinical situation. The measurement at the midpoint of the duct is more reliable than at the external aperture. The conductive component in EVA Syndrome with mixed hearing loss is present only at the lower frequencies (250, 500 Hz), not at the middle and higer frequencies. Long-term follow-up of hearing should be done in the borderline cases with check-up of PDS gene anomaly if necessary. (author)

Open-globe injuries: the experience at Hospital Sultanah Aminah, Johor Bahru.

Science.gov (United States)

Hooi, S H; Hooi, S T

2003-08-01

Between 1st January 1999 and 31st December 2000, 152 patients (156 eyes) with open-globe injuries were treated in the Department of Ophthalmology, Hospital Sultanah Aminah, Johor Bahru. The majority were male (88.2%), Malay (63.2%), from the Johor Bahru district (51.3%) and aged between 21 and 30 years (23.7%). Most injuries were workplace-related (41.4%). Lens injury, retinal detachment, endophthalmitis, intraocular foreign bodies and phthisis occurred in 40.4%, 15.4%, 14.7%, 12.2% and 11.5% of eyes respectively. A favourable visual outcome occurred in 55.4% of eyes. Prognostic factors for visual outcome include presenting visual acuity, relative afferent pupillary defect, wound location, lens injury, retinal detachment and endophthalmitis.

Bronchial compression by an enlarged left atrium in infants; a cause of hypovascularity of the left lung

Energy Technology Data Exchange (ETDEWEB)

Corr, L.; Hallidie-Smith, K.A.; McCarthy, P.A.; Lavender, J.P.

1988-09-01

In three infants seen recently at our institution we noted signs of compression of the left main bronchus associated with enlarged left atria. None of our cases demonstrated the more usual signs of hyperinflation which are a hyperlucent lung field, depressed hemidiaphragm and mediastinal shift away from the affected side. In addition, hypoperfusion of the left lung was noted in each case. We believe that bronchial compression due to an enlarged left atrium, with consequent hypoxic vasoconstriction is a clinically significant entity, which is not well described and may be unappreciated in infants in whom the typical signs of hyperinflation are absent.

Efficient stereological approaches for the volumetry of a normal or enlarged spleen from MDCT images

Energy Technology Data Exchange (ETDEWEB)

Mazonakis, Michalis; Stratakis, John; Damilakis, John [University of Crete, Department of Medical Physics, Faculty of Medicine, P.O. Box 2208, Iraklion, Crete (Greece)

2015-06-01

To introduce efficient stereological approaches for estimating the volume of a normal or enlarged spleen from MDCT. All study participants underwent an abdominal MDCT. The first group included 20 consecutive patients with splenomegaly and the second group consisted of 20 subjects with a normal spleen. Splenic volume estimations were performed using the stereological point counting method. Stereological assessments were optimized using the systematic slice sampling procedure. Planimetric measurements based on manual tracing of splenic boundaries on each slice were taken as reference values. Stereological analysis using five to eight systematically sampled slices provided enlarged splenic volume estimations with a mean precision of 4.9 ± 1.0 % in a mean time of 2.3 ± 0.4 min. A similar measurement duration and error was observed for normal splenic volume assessment using four to seven systematically selected slices. These stereological approaches slightly but insignificantly overestimated the volume of a normal and enlarged spleen compared to planimetry (P > 0.05) with a mean difference of -1.3 ± 4.3 % and -2.7 ± 5.2 %, respectively. The two methods were highly correlated (r ≥ 0.96). The variability of repeated stereological estimations was below 3.8 %. The proposed stereological approaches enable the rapid, reproducible, and accurate splenic volume estimation from MDCT data in patients with or without splenomegaly. (orig.)

Comparative evaluation of oral hygiene status and gingival enlargement among epileptic and healthy children as related to various antiepileptic drugs

Directory of Open Access Journals (Sweden)

Neelam Hasmukhbhai Joshi

2017-01-01

Full Text Available Background: Epilepsy is a gathering of neurological disorders characterized by epileptic seizures. Epileptic children, who are on active treatment with antiepileptic drugs, have a well-recognized side effect of gingival enlargement. Therefore, all efforts should be made, particularly for the population who are diagnosed or affected by the systemic disease. This study was conducted with an aim to determine oral hygiene status and gingival enlargement among epileptic and healthy children as related to various antiepileptic drugs. Materials and Methods: The cross-sectional observational study was conducted in the department of pedodontics and attached general hospital. A sample size of 120 participants with 60 healthy and 60 epileptic children between age 2 and 14 years were included. Oral health status of participants was examined using oral hygiene simplified index and plaque index. Gingival enlargement was assessed using Miranda–Brunet index. For statistical analysis, one-way ANOVA test, independent t-test, and Pearson's Chi-square test were used. Results: From the total participants included in the study, 49% of participants had good oral hygiene from healthy group, and 28% participants had poor oral hygiene from the epileptic group. Sodium valproate was the most common drug used and was associated with increased gingival enlargement. Conclusion: Conclusion can be drawn that epileptic children under medication had poor oral hygiene and an increased risk for gingival enlargement as compared to their healthy counterparts. It must be stressed that the epileptic patients should be given dental care without conditions and provided with best possible care to restore esthetics and functions.

Patient with bilateral breast enlargement and hypospadias.

Science.gov (United States)

Ali, A A; Ahmed, T; Rashid, M M

2009-01-01

A 20 year old man was admitted in the surgical unit of Dhaka Medical College Hospital on August 2007 presented with Hypospadias & underdeveloped penis from childhood, gradual enlargement of both breasts for the last 10 years, absence of axillary and pubic hair from puberty & painful swelling of both testes for the last 3 years. The patient was regarded as a female upto the age of 10 years. He has got no voice change since puberty. On examination he had average body built, there was bilateral gynaecomastia, hypospadias, rudimentary penis & absence of pubic and axillary hair. His testosterone level, serum prolactin level, serum progesterone level, serum estradiol level was done. Cytology on buccal smear done and ultrasonography revealed no ovary and uterus. Ultimately patient was diagnosed as a case of androgen insensitivity syndrome (AIS). The case is reported for clinical awareness & to share our experience.

Outer retinal tubulation as a predictor of the enlargement amount of geographic atrophy in age-related macular degeneration.

Science.gov (United States)

Hariri, Amirhossein; Nittala, Muneeswar G; Sadda, SriniVas R

2015-02-01

To determine the prognostic value of outer retinal tubulation (ORT) in the enlargement amount of geographic atrophy (GA) in eyes with age-related macular degeneration (AMD). Cohort study. One hundred eight fellow untreated eyes of 143 patients with GA resulting from AMD enrolled in the MAHALO study (clinicaltrials.gov identifier, NCT01229215) who completely satisfied the study term and had gradable spectral-domain optical coherence tomography (OCT) images obtained at both baseline and month 18 visits. The MAHALO study enrolled 143 subjects into a phase 1b/2 multicenter, randomized, single-masked, sham-injection controlled clinical trial of the safety, tolerability, and evidence of activity of lampalizumab in patients with GA associated with AMD. Spectral-domain optical coherence tomography images were obtained at multiple time points in both eyes, although only the baseline and month 18 data of the fellow (nonstudy) eyes were considered in this exploratory analysis. The Cirrus HD-OCT review software was used for automatic segmentation and measurement of GA areas, with manual correction of segmentation errors by certified OCT graders. Baseline OCT images also were assessed for the presence of ORT. The enlargement amount of GA in eyes with ORT was compared with that of eyes without ORT. Comparison of the enlargement amount of GA in eyes with and without ORT. Twenty-four of these 108 eyes demonstrated evidence of ORT. The amount of enlargement of GA in eyes with ORT was significantly slower than that of eyes without ORT (1.85±0.78 vs. 2.67±1.61; P = 0.001). This difference remained significant when considering subgroups with unifocal or multifocal GA lesions, because eyes with ORT in both subgroups had a slower enlargement amount of GA than eyes without ORT (2.91±1.70 vs. 2.08±0.88 [P = 0.01], in eyes with multifocal GA lesions; and 2.24±1.40 vs. 1.63±0.57 [P = 0.02], in eyes with unifocal GA lesions). In eyes with ORT, GA lesions seem to enlarge at a

Analysis of a monetary union enlargement in the framework of linear-quadratic differential games

NARCIS (Netherlands)

Plasmans, J.E.J.; Engwerda, J.C.; van Aarle, B.; Michalak, T.

2009-01-01

"This paper studies the effects of a monetary union enlargement using the techniques and outcomes from an extensive research project on macroeconomic policy coordination in the EMU. Our approach is characterized by two main pillars: (i) linear-quadratic differential games to capture externalities,

Explosive (chemical) substances. 6. rev. and enlarged ed. Explosivstoffe

Energy Technology Data Exchange (ETDEWEB)

Meyer, R

1985-01-01

The sixth edition of this review manual again has been enlarged and actualized, the proved concept has been maintained. The text describes in large more than 550 items alphabetically, among them about 120 chemical compounds attributed with structure formulas and data. The properties, preparation procedures, and application possibilities of these substances and of about 70 additives, fuels and oxidants are presented for the reader. By nearly 1500 keywords in the index, English and French translations, and explanations of abbreviations, this book becomes a comprehensive and actual dictionary, not only for the specialist, but also for translators, interpreters, newspaper editors, and patent lawyers. (orig./HK).

Painful unilateral temporalis muscle enlargement: reactive masticatory muscle hypertrophy.

Science.gov (United States)

Katsetos, Christos D; Bianchi, Michael A; Jaffery, Fizza; Koutzaki, Sirma; Zarella, Mark; Slater, Robert

2014-06-01

An instance of isolated unilateral temporalis muscle hypertrophy (reactive masticatory muscle hypertrophy with fiber type 1 predominance) confirmed by muscle biopsy with histochemical fiber typing and image analysis in a 62 year-old man is reported. The patient presented with bruxism and a painful swelling of the temple. Absence of asymmetry or other abnormalities of the craniofacial skeleton was confirmed by magnetic resonance imaging and cephalometric analyses. The patient achieved symptomatic improvement only after undergoing botulinum toxin injections. Muscle biopsy is key in the diagnosis of reactive masticatory muscle hypertrophy and its distinction from masticatory muscle myopathy (hypertrophic branchial myopathy) and other non-reactive causes of painful asymmetric temporalis muscle enlargement.

Northern Steps of EU Enlargement: The Impact of “Cohesion” Policies on Iceland’s Accession Process

Directory of Open Access Journals (Sweden)

Adriana Di Stefano

2011-03-01

Full Text Available This paper focuses on the EU accession process of Iceland, reading the latest northern steps of EU enlargement under a “cohesion” perspective, i.e., through the lens of the cohesion “theory”, namely the method resulting from interactions of the general principles of subsidiarity and cooperation or partnership. From the Mediterranean to the Arctic, the territorial dimension of cohesion policies, as grounded in different EU policies, plays different roles and meets a wide range of economic and social needs. By implementing Nordicum-Mediterraneum analogies, a cohesion-minded EU enlargement approach requires the overall reframing of territorial-based policies and a better allocation of shared responsibilities at the more efficient level of governance.

Unusual presentation of hidradenitis suppurativa with massive enlargement of penis.

Science.gov (United States)

Baughman, Steven M; Cespedes, R Duane

2004-08-01

Hidradenitis suppurativa is a chronic, recurrent inflammatory disease affecting the cutaneous apocrine glands and resulting in their obstruction. This enigmatic disease causes recurrent episodes of infection, edema, scarring, and fibrosis of surrounding tissues. We present the case of a 55-year-old man with two decades of inguinal hidradenitis suppurativa that resulted in extensive penile subcutaneous lymphedema and enlargement secondary to scarring and obstructive lymphadenopathy. Reconstructive phalloplasty to restore normal penile function was required. Minimal recurrent induration, normal cutaneous sensation, and normal voiding and erectile function were noted at 3 years of follow-up.

Globe Event | Lecture by Cédric Villani | 21 May

CERN Multimedia

Globe Info

2013-01-01

La naissance des idées - réflexions sur la nature et l’histoire de la mathématique et de la physique, by Cédric Villani.   Globe de la science et de l'innovation Route de Meyrin, 1211 Genève Tuesday 21 May 2013 at 6:00 p.m. The lecture will be in French - Interpreting available in English   Cédric Villani. In this lecture, Cédric Villani will explain what he considers to be the necessary “ingredients” for the birth of new ideas. Clearly a good brain is an essential factor, but that alone is not enough. The researcher must also have access to a wealth of literature, which is now greatly facilitated by the Internet. Motivation is another key component, although we do not really understand what incites it. Intellectual environment and constraints also drive creativity, as do perseverance and chance. An interesting idea has little chance of making a breakthrough w...

CONNECTING THE ENLARGEMENT PROCESS WITH THE EUROPEANIZATION THEORY (THE CASE OF TURKEY

Directory of Open Access Journals (Sweden)

Teodor Lucian Moga

2010-03-01

Full Text Available Europeanization is one of the theoretical instruments which had a vital influence on candidate countries for EU membership. Due to its aspirations of becoming member of the European Union (EU and in its attempt to fulfil the Copenhagen criteria, Turkey is trying to comply with the EU acquis communautaire. The aim of this paper is to assess the effects of the Europeanization process on the countries subject to EU enlargement strategy, with a special focus on Turkey, particularly since the country received the EU candidate status in 1999. This paper has been organized in the following way: firstly, it points out how both the traditional Europeanization and the enlargement led Europeanization have been depicted in the work of several important scholars; secondly, by offering a short overview of Turkey’s foreign relations vis-à-vis its neighbourhood, especially in the last decade, it examines how the mechanism of Europeanization largely influenced the country’s diplomatic culture. Traditionally, Turkey has been attuned to hard security issues and architectures. However, the Turkish foreign policy strategy emphasised in thepast years the Venus side of things in many settings in line with EU requirements.

Effect of nitrogen fertilisation on the overall quality of minimally processed globe artichoke heads.

Science.gov (United States)

Lombardo, Sara; Restuccia, Cristina; Muratore, Giuseppe; Barbagallo, Riccardo N; Licciardello, Fabio; Pandino, Gaetano; Scifò, Giovanna O; Mazzaglia, Agata; Ragonese, Francesca; Mauromicale, Giovanni

2017-01-01

Although nitrogen (N) fertilisation is essential for promoting crop yield, it may also affect the produce quality. Here, the influence of three N fertiliser rates (0 kg ha -1 as a control, 200 kg ha -1 and 400 kg ha -1 referred to as N 0 , N 200 and N 400 , respectively) on the overall quality of minimally processed globe artichoke heads was investigated during refrigerated storage for 12 days. Throughout the storage time, N fertilised samples had higher inulin contents than those unfertilised. In addition, the respiratory quotient of N 200 and N 400 samples was 2-fold and 2.5-fold lower than N 0 ones, whose values were close to the normal range for vegetables. All the samples reported good microbiological standards, although N 200 and N 400 achieved lower mesophilic and psychotropic counts than N 0 throughout the storage time. After 8 and 12 days of refrigerated storage, the N 200 samples showed the highest scores of positive sensory descriptors. A fertiliser level of 200 kg N ha -1 is suitable for obtaining minimally processed globe artichoke heads with good nutritional, sensory and microbiological quality, characterised by low endogenous oxidase activities. Proper packaging systems and procedures are, however, crucial for extending the product shelf-life and, thus, promoting its exportation on a wider scale. © 2016 Society of Chemical Industry. © 2016 Society of Chemical Industry.

Challenges to NATO’s Fifth Enlargement Round: Turkey’s Attitude towards Romanian’s Admission

Directory of Open Access Journals (Sweden)

İsmail Köse

2015-12-01

Full Text Available The relations between Romania – the only Latin nation in Balkan Peninsula, in a broader sense – and Turkey has a long history, which is traced back to the Ottoman period. These relations were relatively ceased during the Cold War. After the collapse of Soviet Union, a new era started for Turkish-Romanian relations. During the WWI, Tsarist Russia forced Romania to be its ally, in order to besiege Germany from South, and also to threat Austria. Its aim was intended to direct the Central Powers’ attacks to the Balkans, in order to keep the warfare away from the front lines and from the Russian heartland. Following the Tsarist pan-Slavist policy, the Bolshevist Russia designated Balkans territories as vital for its security and defence. At the first opportunity emerged after the WWII, Stalin had included those lands behind the Iron Curtain area. After a fairly lengthy period under the Iron Curtain, after 1989, Romania like other eastern European countries achieved its freedom, but post-Cold War attitude of Russia towards the Balkans has remained unchanged. This paper seeks to explore the post-Cold War policies of NATO and the Turkey’s attitude towards the enlargements of alliance. It focuses on the fifth round of enlargement, when Romania and other six Balkans and Baltic countries were invited to join the North Atlantic Alliance. In addition, it will insist on the role of Turkey in the enlargement process, and its firm support for Romania's accession to NATO.

Predictive value of ocular trauma score in open globe combat eye injuries

International Nuclear Information System (INIS)

Islam, Q.

2016-01-01

Prediction of final visual outcome in ocular injuries is of paramount importance and various prognostic models have been proposed to predict final visual outcome. The objective of this study was to validate the predictive value of ocular trauma score (OTS) in patients with combat related open globe injuries and to evaluate the factors affecting the final visual outcome. Methods: Data of 93 patients admitted in AFIO Rawalpindi between Jan 2010 to June 2014 with combat related open globe ocular injuries was analysed. Initial and final best corrected visual acuity (BCVA) was categorized as No Light Perception (NLP), Light Perception (LP) to Hand Movement (HM), 1/200-19/200, 20/200-20/50, and =20/40. OTS was calculated for each eye by assigning numerical raw points to six variables and then scores were stratified into five OTS categories. Results: Mean age of study population was 28.77 ± 8.37 years. Presenting visual acuity was <20/200 (6/60) in 103 (96.23%) eyes. However, final BCVA of =20/40 (6/12) was achieved in 18 (16.82%) eyes, while 72 (67.28%) eyes had final BCVA of <20/200 (6/60). Final visual outcome in our study were similar to those in OTS study, except for NLP in category 1 (81% vs. 74%) and =20/40 in category 3 (30% vs. 41%). The OTS model predicted visual survival (LP or better) with a sensitivity of 94.80% and predicted no vision (NLP) with a specificity of 100%. Conclusion: OTS is a reliable tool for assessment of ocular injuries and predicting final visual outcome at the outset. (author)

Laboratory determination of normal operating flow rates with enlarged outlet fittings -- BDF reactors

Energy Technology Data Exchange (ETDEWEB)

Waters, E.D.

1960-02-02

Experiments have been conducted in the Hydraulics Laboratory, at the request of IPD`s Mechanical Development-A Operation, to determine the energy losses of various enlarged outlet fitting combinations. These experiments were conducted an steady state runs and allow the determination of the normal operating point (flow rate) of a reactor process channel under selected conditions of front header pressure and fuel charge. No attempt is made to make a mechanical or economic evaluation of the particular fitting combinations, although observations were noted which might bear on this evaluation. It is very important for the reader to bear in mind that changing outlet fittings will definitely affect the reactor tube power limits and outlet vater temperature limits. The size of the outlet fittings largely determines the present outlet temperature limits of the old reactors. The flow characteristics of these present fittings cause some degree of pressurization to suppress boiling on the fuel charge and also cause dual Panellit trip protection for certain flow changes and for power surges. Enlargement of the outlet fittings may actually reduce the allowable outlet coolant temperature limits. Since these effects cannot be determined on the apparatus used in these experiments, a complete discussion of this point is not included in this report. However, the seriousness of these effects should be known and carefully analyzed before a final selection of enlarged outlet fittings in made. This report will be one of a series. New reports in the series will be issued as data are obtained for other such outlet fitting combinations or for new concepts of outlet fitting assemblies such as the new nozzle being developed by C. E. Trantz for use on F-reactor stuck gunbarrel tubes.

Subsidy policy and the enlargement of choice

International Nuclear Information System (INIS)

Srinivasan, Sunderasan

2009-01-01

Development is the enlargement of people's choices. Optimal subsidy policy is intended to create the right incentives for each of the value chain participants. This paper contends that the interest subsidy offered by the Indian federal Ministry of New and Renewable Energy for solar thermal systems, through mainstream banking channels is superior in intent and outcome compared to the capital subsidy as currently offered for solar PV systems, routed through government controlled delivery channels. The interest subsidy enhances innovation, improves service delivery and expands the range of product available to consumers enjoying a wide range of endowments, thus leading to more inclusive development. The simple monopoly model developed by Atkinson [Atkinson AB. Capabilities, exclusion and the supply of goods. In: Basu K, Pattanaik P, Suzumura K, editor, Choice, Welfare and Development. Oxford University Press; 1995] is applied to the context of solar home systems to demonstrate price reduction and choice expansion in a liberalized market, facilitated by an interest subsidy scheme. (author)

Point-of-service, quantitative analysis of ascorbic acid in aqueous humor for evaluating anterior globe integrity

Science.gov (United States)

Gartia, Manas R.; Misra, Santosh K.; Ye, Mao; Schwartz-Duval, Aaron; Plucinski, Lisa; Zhou, Xiangfei; Kellner, David; Labriola, Leanne T.; Pan, Dipanjan

2015-11-01

Limited training, high cost, and low equipment mobility leads to inaccuracies in decision making and is concerning with serious ocular injuries such as suspected ruptured globe or post-operative infections. Here, we present a novel point-of-service (POS) quantitative ascorbic acid (AA) assay with use of the OcuCheck Biosensor. The present work describes the development and clinical testing of the paper-based biosensor that measures the changes in electrical resistance of the enzyme-plated interdigitated electrodes to quantify the level of AA present in ocular fluid. We have demonstrated the proof-of-concept of the biosensor testing 16 clinical samples collected from aqueous humor of patients undergoing therapeutic anterior chamber paracentesis. Comparing with gold standard colorimetric assay for AA concentration, OcuCheck showed accuracy of >80%, sensitivity of >88% and specificity of >71%. At present, there are no FDA-approved POS tests that can directly measures AA concentration levels in ocular fluid. We envisage that the device can be realized as a handheld, battery powered instrument that will have high impact on glaucoma care and point-of-care diagnostics of penetrating ocular globe injuries.

Total Maxillary Reconstruction With a Bi-Paddle Double-Barrel Osteocutaneous Fibular Flap and Arteriovenous Saphenous Loop After a Globe-Sparing Total Maxillectomy Due to Osteosarcoma.

Science.gov (United States)

Tseng, Wan-Ling; Chang, Tzu-Yen; Hung, Kuo-Shu; Chen, Szu-Han; Hsiao, Jenn-Ren; Lee, Yao-Chou

2017-01-01

The titanium mesh or bone graft is usually used for orbital support after a globe-sparing total maxillectomy. However, its use can invite complications, such as infection, exposure, and absorption, especially for patients who require adjuvant radiotherapy. Here, the authors present a patient who received total maxillary reconstruction with an osteocutaneous fibular flap. A 53-year-old man with the diagnosis of maxillary osteosarcoma received a globe-sparing total maxillectomy. A bi-paddle double-barrel osteocutaneous fibular flap was used for orbital support, alveolar ridge recreation, and oro-sino-nasal separation. The short pedicle length inherent in the double-barrel design of the fibular flap was overcome by creating an arteriovenous saphenous loop. The postoperative recovery was uneventful. During the 9 months follow-up, the patient was tumor-free and satisfied with his appearance, speech, and intake functions. Reconstruction with a bi-paddle double-barrel osteocutaneous fibular flap after a globe-sparing total maxillectomy can achieve satisfactory aesthetic and functional results.

Acrolein Induces Endoplasmic Reticulum Stress and Causes Airspace Enlargement

Science.gov (United States)

Hanaoka, Masayuki; Natarajan, Ramesh; Kraskauskas, Donatas; Voelkel, Norbert F.

2012-01-01

Background Given the relative abundance and toxic potential of acrolein in inhaled cigarette smoke, it is surprising how little is known about the pulmonary and systemic effects of acrolein. Here we test the hypothesis whether systemic administration of acrolein could cause endoplasmic reticulum (ER) stress, and lung cell apoptosis, leading to the enlargement of the alveolar air spaces in rats. Methods Acute and chronic effects of intraperitoneally administered acrolein were tested. Mean alveolar airspace area was measured by using light microscopy and imaging system software. TUNEL staining and immunohistochemistry (IHC) for active caspase 3 and Western blot analysis for active caspase 3, and caspase 12 were performed to detect apoptosis. The ER-stress related gene expression in the lungs was determined by Quantitative real-time PCR analysis. Acrolein-protein adducts in the lung tissue were detected by IHC. Results Acute administration of acrolein caused a significant elevation of activated caspase 3, upregulation of VEGF expression and induced ER stress proteins in the lung tissue. The chronic administration of acrolein in rats led to emphysematous lung tissue remodeling. TUNEL staining and IHC for cleaved caspase 3 showed a large number of apoptotic septal cells in the acrolein-treated rat lungs. Chronic acrolein administration cause the endoplasmic reticulum stress response manifested by significant upregulation of ATF4, CHOP and GADd34 expression. In smokers with COPD there was a considerable accumulation of acrolein-protein adducts in the inflammatory, airway and vascular cells. Conclusions Systemic administration of acrolein causes endoplasmic reticulum stress response, lung cell apoptosis, and chronic administration leads to the enlargement of the alveolar air spaces and emphysema in rats. The substantial accumulation of acrolein-protein adducts in the lungs of COPD patients suggest a role of acrolein in the pathogenesis of emphysema. PMID:22675432

Survey of Fertility Preservation Options Available to Patients With Cancer Around the Globe

Directory of Open Access Journals (Sweden)

Alexandra S. Rashedi

2017-06-01

Full Text Available Purpose: Oncofertility focuses on providing fertility and endocrine-sparing options to patients who undergo life-preserving but gonadotoxic cancer treatment. The resources needed to meet patient demand often are fragmented along disciplinary lines. We quantify assets and gaps in oncofertility care on a global scale. Methods: Survey-based questionnaires were provided to 191 members of the Oncofertility Consortium Global Partners Network, a National Institutes of Health–funded organization. Responses were analyzed to measure trends and regional subtleties about patient oncofertility experiences and to analyze barriers to care at sites that provide oncofertility services. Results: Sixty-three responses were received (response rate, 25%, and 40 were analyzed from oncofertility centers in 28 countries. Thirty of 40 survey results (75% showed that formal referral processes and psychological care are provided to patients at the majority of sites. Fourteen of 23 respondents (61% stated that some fertility preservation services are not offered because of cultural and legal barriers. The growth of oncofertility and its capacity to improve the lives of cancer survivors around the globe relies on concentrated efforts to increase awareness, promote collaboration, share best practices, and advocate for research funding. Conclusion: This survey reveals global and regional successes and challenges and provides insight into what is needed to advance the field and make the discussion of fertility preservation and endocrine health a standard component of the cancer treatment plan. As the field of oncofertility continues to develop around the globe, regular assessment of both international and regional barriers to quality care must continue to guide process improvements.

GlobeLand30 shows little cropland area loss but greater fragmentation in China

Science.gov (United States)

Yu, Qiangyi; Hu, Qiong; van Vliet, Jasper; Verburg, Peter H.; Wu, Wenbin

2018-04-01

Understanding of cropland dynamics in a large geographical extent is mostly based on observations of area change, while the changes in landscape pattern are hardly assessed. The total amount of cropland in China has remained relatively stable in recent years, which might suggest there was little change. In this analysis, we combine the number of cropland patches (NP) with the total cropland area (TA) for a more comprehensive characterization of cropland change in China. We use GlobeLand30-a global land cover dataset with a 30 m resolution for the years 2000 and 2010-and characterize changes in TA and NP for each county as increase, stable, or decrease. This characterization shows that 703 out of 2420 counties experienced both cropland loss and increased fragmentation. The predominant cropland loss in these areas, especially in the North China Plain, is converted to artificial land. Another 212 are characterized by the opposite developments: an increase in cropland and decreased fragmentation. These counties, are mainly characterized by a conversion of forest areas and grassland areas. It suggests that the cropland conservation policy in China effectively protected the total cropland area in overall, but the consequences in terms of fragmentation might be underestimated. Counties with no obvious change in both indicators, measuring 279 counties, are mainly located in the Southeast. Our results are further compared with local level case studies: the fair consistency indicates alternatives of applying GlobeLand30 for analyzing landscape changes across scales and for cross-site comparisons.

Trepanation and enlarged parietal foramen on skulls from the Loyalty Islands (Melanesia).

Science.gov (United States)

Vasilyev, Sergey V; Sviridov, Alexey A

2017-06-01

The goal of this study is a comprehensive examination of openings discovered on two skulls in the collection of skeletal remains from the Loyalty Islands (Melanesia). The skull No. 1524 displayed an evidence of successful trepanation, and the skull No. 7985 revealed openings that were reminiscent of a trepanation, however, we are inclined to believe that in the latter case we are dealing with a rare genetic anomaly - enlarged parietal foramen.

Modernization and enlarging of the Marcoule pilot plant for R and D

International Nuclear Information System (INIS)

Calame-Longjean, A.; Revol, G.; Roux, J.P.; Ranger, G.

1987-01-01

The aim of the pilot plant is the testing of process and equipment in actual conditions with spent fuels on a half-industrial scale and for a significant time. From 1963 to 1983 more than 11t of spent fuels (mainly from fast reactors) were reprocessed. Since 1983 is modernized and enlarged and the new plant of the TOR project (treatment of oxides from fast reactors) are described [fr

The Design, Implementation, and Evaluation of a Digital Interactive Globe System Integrated into an Earth Science Course

Science.gov (United States)

Liou, Wei-Kai; Bhagat, Kaushal Kumar; Chang, Chun-Yen

2018-01-01

The aim of this study is to design and implement a digital interactive globe system (DIGS), by integrating low-cost equipment to make DIGS cost-effective. DIGS includes a data processing unit, a wireless control unit, an image-capturing unit, a laser emission unit, and a three-dimensional hemispheric body-imaging screen. A quasi-experimental study…

A Digitally Programmable Differential Integrator with Enlarged Time Constant

Directory of Open Access Journals (Sweden)

S. K. Debroy

1994-12-01

Full Text Available A new Operational Amplifier (OA-RC integrator network is described. The novelties of the design are used of single grounded capacitor, ideal integration function realization with dual-input capability and design flexibility for extremely large time constant involving an enlargement factor (K using product of resistor ratios. The aspect of the digital control of K through a programmable resistor array (PRA controlled by a microprocessor has also been implemented. The effect of the OA-poles has been analyzed which indicates degradation of the integrator-Q at higher frequencies. An appropriate Q-compensation design scheme exhibiting 1 : |A|2 order of Q-improvement has been proposed with supporting experimental observations.

Validation of the Automated Method VIENA: An Accurate, Precise, and Robust Measure of Ventricular Enlargement

NARCIS (Netherlands)

Vrenken, H.; Vos, E.K.; van der Flier, W.M.; Sluimer, I.C.; Cover, K.S.; Knol, D.L.; Barkhof, F.

2014-01-01

Background: In many retrospective studies and large clinical trials, high-resolution, good-contrast 3DT1 images are unavailable, hampering detailed analysis of brain atrophy. Ventricular enlargement then provides a sensitive indirect measure of ongoing central brain atrophy. Validated automated

Wet-bulb globe temperature (WBGT)--its history and its limitations.

Science.gov (United States)

Budd, Grahame M

2008-01-01

Wet-bulb globe temperature (WBGT) is nowadays the most widely used index of heat stress, yet many users appear to be unaware of its history and its limitations. HISTORY OF WBGT: WBGT was invented and first used during the 1950s as one element in a successful campaign to control serious outbreaks of heat illness in training camps of the United States Army and Marine Corps. Control measures based on air temperature and humidity, and applied to all trainees alike, had proved effective but had entailed excessive compliance costs in the form of lost training time. New control measures introduced in 1956 further reduced heat illness and also lost fewer training hours. Crucial innovations were (1) replacing the temperature and humidity measurements with WBGT, which additionally responds to sun and wind, (2) using epidemiologic analyses of casualty records to identify hazardous levels of WBGT and vulnerable trainees, and (3) protecting the most vulnerable trainees by suspending drill at lower levels of WBGT, and by improving their heat tolerance in special conditioning platoons. This campaign has considerable relevance to the prevention of heat illness in sport. LIMITATIONS OF WBGT: WBGT's most serious limitation is that environments at a given level of the index are more stressful when the evaporation of sweat is restricted (by high humidity or low air movement) than when evaporation is free. As with all indices that integrate elements of the thermal environment, interpretation of the observed levels of WBGT requires careful evaluation of people's activity, clothing, and many other factors, all of which can introduce large errors into any predictions of adverse effects. Moreover, the accuracy of WBGT is being eroded by measurement errors associated with the omission of the globe temperature, with non-standard instrumentation, and with unsatisfactory calibration procedures. Because of the above limitations WBGT can provide only a general guide to the likelihood of adverse

The Eurosafe Forum 2003: Nuclear expertise and challenges of the enlargement of the European Union

Energy Technology Data Exchange (ETDEWEB)

Lacronique, Jean-Francois; Repussard, Jacques [Institut de Radioprotection et de Surete Nucleaire, IRSN, B.P. 17, F - 92262 Fontenay-aux-Roses Cedex (France); Hahn, Lothar [Gesellschaft fuer Anlagen- und Reaktorsicherheit mbH, GRS, Schwertnergasse 1, D - 50667 Koeln (Germany)

2003-07-01

EUROSAFE is an international forum for discussions among experts from technical safety organisations, research institutes, safety authorities, utilities, the industry, public authorities and non-governmental organisations concerning the status of and recent achievements in nuclear installation safety, waste management, radiation safety and nuclear material security. The Eurosafe Forum 2003 - the fifth of its kind - was held at the Palais Brongniart in Paris on November 25 and 26, 2003. This year's theme was: 'Nuclear expertise and challenges of the enlargement of the European Union: speakers in the various European countries about the environmental scan before enlargement, development and structuring perspectives within the enlarged Europe'. The event brought together 445 experts and researchers from around the world (including 124 from Germany, 184 from France, 88 from Eastern Europe, as well as representatives from Korea, Japan, the United States, Canada, Cuba, and Armenia. The proceedings of the symposium can now be consulted online. The fifth edition of the forum focused on nuclear expertise and the challenge of EU-enlargement and the latest work carried out by GRS, IRSN and their partners from the European Union, Switzerland and Eastern Europe. Nuclear energy contributes approximately one third of European electricity production. A high level of nuclear safety is a priority for the countries of Europe. The technical safety organisations play an important role in contributing to that objective through appropriate approaches to major safety issues as part of their assessments and research activities. The challenges to nuclear safety are increasingly international. Changes in underlying technologies such as instrumentation and control, the impact of electricity market deregulation, demands for improved safety, the ageing of nuclear facilities, waste management, maintaining and improving scientific and technical knowledge and the need for greater transparency

The Eurosafe Forum 2003: Nuclear expertise and challenges of the enlargement of the European Union

International Nuclear Information System (INIS)

Lacronique, Jean-Francois; Repussard, Jacques

2003-01-01

EUROSAFE is an international forum for discussions among experts from technical safety organisations, research institutes, safety authorities, utilities, the industry, public authorities and non-governmental organisations concerning the status of and recent achievements in nuclear installation safety, waste management, radiation safety and nuclear material security. The Eurosafe Forum 2003 - the fifth of its kind - was held at the Palais Brongniart in Paris on November 25 and 26, 2003. This year's theme was: 'Nuclear expertise and challenges of the enlargement of the European Union: speakers in the various European countries about the environmental scan before enlargement, development and structuring perspectives within the enlarged Europe'. The event brought together 445 experts and researchers from around the world (including 124 from Germany, 184 from France, 88 from Eastern Europe, as well as representatives from Korea, Japan, the United States, Canada, Cuba, and Armenia. The proceedings of the symposium can now be consulted online. The fifth edition of the forum focused on nuclear expertise and the challenge of EU-enlargement and the latest work carried out by GRS, IRSN and their partners from the European Union, Switzerland and Eastern Europe. Nuclear energy contributes approximately one third of European electricity production. A high level of nuclear safety is a priority for the countries of Europe. The technical safety organisations play an important role in contributing to that objective through appropriate approaches to major safety issues as part of their assessments and research activities. The challenges to nuclear safety are increasingly international. Changes in underlying technologies such as instrumentation and control, the impact of electricity market deregulation, demands for improved safety, the ageing of nuclear facilities, waste management, maintaining and improving scientific and technical knowledge and the need for greater transparency

The Eurosafe Forum 2003: Nuclear expertise and challenges of the enlargement of the European Union

Energy Technology Data Exchange (ETDEWEB)

Lacronique, Jean-Francois; Repussard, Jacques (eds.) [Institut de Radioprotection et de Surete Nucleaire, IRSN, B.P. 17, F - 92262 Fontenay-aux-Roses Cedex (France); Hahn, Lothar (ed.) [Gesellschaft fuer Anlagen- und Reaktorsicherheit mbH, GRS, Schwertnergasse 1, D - 50667 Koeln (Germany)

2003-07-01

EUROSAFE is an international forum for discussions among experts from technical safety organisations, research institutes, safety authorities, utilities, the industry, public authorities and non-governmental organisations concerning the status of and recent achievements in nuclear installation safety, waste management, radiation safety and nuclear material security. The Eurosafe Forum 2003 - the fifth of its kind - was held at the Palais Brongniart in Paris on November 25 and 26, 2003. This year's theme was: 'Nuclear expertise and challenges of the enlargement of the European Union: speakers in the various European countries about the environmental scan before enlargement, development and structuring perspectives within the enlarged Europe'. The event brought together 445 experts and researchers from around the world (including 124 from Germany, 184 from France, 88 from Eastern Europe, as well as representatives from Korea, Japan, the United States, Canada, Cuba, and Armenia. The proceedings of the symposium can now be consulted online. The fifth edition of the forum focused on nuclear expertise and the challenge of EU-enlargement and the latest work carried out by GRS, IRSN and their partners from the European Union, Switzerland and Eastern Europe. Nuclear energy contributes approximately one third of European electricity production. A high level of nuclear safety is a priority for the countries of Europe. The technical safety organisations play an important role in contributing to that objective through appropriate approaches to major safety issues as part of their assessments and research activities. The challenges to nuclear safety are increasingly international. Changes in underlying technologies such as instrumentation and control, the impact of electricity market deregulation, demands for improved safety, the ageing of nuclear facilities, waste management, maintaining and improving scientific and technical knowledge and the need for greater

Enlarged superior cervical sympathetic ganglion mimicking a metastatic lymph node in the retropharyngeal space: A case report

Energy Technology Data Exchange (ETDEWEB)

Kim, Jae Min; Kim, Jin Na; Kim, Se Hoon; Choi, Eun Chang [Severance Hospital, Yonsei University College of Medicine, Seoul (Korea, Republic of)

2017-04-15

The superior cervical sympathetic ganglion, the largest and most cranial of the three cervical sympathetic ganglia, transfers sympathetic signals to specific targets on the head and neck. This ganglion is located just lateral to the retropharyngeal space along the medial margin of the carotid sheath. Located thus, an enlarged superior cervical sympathetic ganglion can mimic a metastatic lymph node in the retropharyngeal space of the suprahyoid neck in head and neck cancer patients. However, this is often disregarded by radiologists due to lack of interest in its anatomic location. We present a case of an enlarged superior cervical sympathetic ganglion mimicking a retropharyngeal metastatic lymph node in a 42-year-old man with oral tongue cancer.

GINGIVAL ENLARGEMENT ASSOCIATED WITH NOCTURNAL FRONTAL LOBE EPILEPSY. A CASE REPORT

Directory of Open Access Journals (Sweden)

Sharma ANAMIKA

2012-12-01

Full Text Available „Epilepsy” refers to a group of neurological disorders characterized by chronic, recurrent, paroxysmal seizure activity. Nocturnal frontal lobe epilepsy is a neurological disorder characterized by brief, recurring seizures produ‑ ced in the frontal lobes of the brain, often while the patient is sleeping, and also by clusters of brief motor seizures. Seizure disorders may affect the dental status and oral health of patients. Epileptic drugs lead to gingival hyper‑ plasia, namely tissue enlargement, caused by an increased number of cells.

Achondroplasia in children: correlation of ventriculomegaly, size of foramen magnum and jugular foramina, and emissary vein enlargement.

Science.gov (United States)

Bosemani, Thangamadhan; Orman, Gunes; Hergan, Benedikt; Carson, Kathryn A; Huisman, Thierry A G M; Poretti, Andrea

2015-01-01

Achondroplasia is a skeletal dysplasia with diminished growth of the skull base secondary to defective enchondral bone formation. This leads to narrowing of the foramen magnum and jugular foramina, which further leads to ventricular dilatation and prominence of the emissary veins. The primary goal of our study was to determine a correlation between the degree of ventricular dilatation, jugular foramina and foramen magnum narrowing, as well as emissary vein enlargement. Conventional T2-weighted MR images were evaluated for surface area of the foramen magnum and jugular foramina, ventricular dilatation, and emissary veins enlargement in 16 achondroplasia patients and 16 age-matched controls. Ratios were calculated for the individual parameters using median values from age-matched control groups to avoid age as a confounder. Compared to age-matched controls, in children with achondroplasia, the surface area of the foramen magnum (median 0.50 cm(2), range 0.23-1.37 cm(2) vs. 3.14 cm(2), 1.83-6.68 cm(2), p achondroplasia, (1) the variation in ventricular dilatation may be related to an unquantifiable interdependent relationship of emissary vein enlargement, venous channel narrowing, and foramen magnum compression and (2) stable ventricular size facilitated by interdependent factors likely obviates the need for ventricular shunt placement.

Serum total prostate-specific antigen values in men with symptomatic prostate enlargement in Nigeria: role in clinical decision-making

Directory of Open Access Journals (Sweden)

Nnabugwu II

2014-12-01

Full Text Available Ikenna I Nnabugwu,1,2 Fred O Ugwumba,1 Oghenekaro A Enivwenae,2 Emeka I Udeh,1 Chris O Otene,2 Chinwe A Nnabugwu3 1Urology Unit, Department of Surgery, College of Medicine, University of Nigeria, Nsukka, 2Urology Unit, Department of Surgery, 3Department of Medical Laboratory Services, Federal Medical Centre, Asaba, Nigeria Background: Prostatic enlargement is a common cause of bladder outlet obstruction in men in Nigeria. Malignant enlargements must be differentiated from benign enlargements for adequate treatment of each patient. High serum total prostate-specific antigen (tPSA levels suggest malignancy, but some of the biopsies done due to a serum tPSA value >4 ng/mL would be negative for malignancy because of the low specificity of tPSA for prostate cancer. This study aims to compare the histologic findings of all prostate specimens obtained from core needle biopsy, open simple prostatectomy, and transurethral resection of the prostate with the respective serum tPSA values in an attempt to decipher the role of serum tPSA in the management of these patients.Methods: The case notes of patients attended to from April 2009 to March 2012 were analyzed. Essentially, the age of the patient, findings on digital rectal examination, abdominopelvic ultrasonography report on the prostate, serum tPSA, and histology reports from biopsy or prostatectomy specimens as indicated were extracted for analysis.Results: The relationship between age, findings on digital rectal examination, serum tPSA, abdominopelvic ultrasonography report, and histology are compared. A statistically significant relationship existed between a malignant histology and age 65 years and older, suspicious findings on digital rectal examination, suspicious ultrasonography findings, and serum tPSA >10 ng/mL, but not tPSA >4 ng/mL.Conclusion: In Nigerian patients with symptomatic prostate enlargement, serum tPSA should be seen as a continuum with increasing risk of prostate malignancy

Gender-Role Portrayals in Television Advertising Across the Globe.

Science.gov (United States)

Matthes, Jörg; Prieler, Michael; Adam, Karoline

Although there are numerous studies on gender-role portrayals in television advertising, comparative designs are clearly lacking. With content analytical data from a total of 13 Asian, American, and European countries, we study the stereotypical depiction of men and women in television advertisements. Our sample consists of 1755 ads collected in May 2014. Analyzing the gender of the primary character and voiceover, as well as the age, associated product categories, home- or work setting, and the working role of the primary character, we concluded that gender stereotypes in TV advertising can be found around the world. A multilevel model further showed that gender stereotypes were independent of a country's gender indices, including Hofstede's Masculinity Index, GLOBE's Gender Egalitarianism Index, the Gender-related Development Index, the Gender Inequality Index, and the Global Gender Gap Index. These findings suggest that gender stereotyping in television advertising does not depend on the gender equality prevalent in a country. The role of a specific culture in shaping gender stereotypes in television advertising is thus smaller than commonly thought.

Cryptococcus neoformans capsular enlargement and cellular gigantism during Galleria mellonella infection.

Directory of Open Access Journals (Sweden)

Rocío García-Rodas

Full Text Available We have studied infection of Cryptococcus neoformans in the non-vertebrate host Galleria mellonella with particular interest in the morphological response of the yeast. Inoculation of C. neoformans in caterpillars induced a capsule-independent increase in haemocyte density 2 h after infection. C. neoformans manifested a significant increase in capsule size after inoculation into the caterpillar. The magnitude of capsule increase depended on the temperature, being more pronounced at 37°C than at 30°C, which correlated with an increased virulence of the fungus and reduced phagocytosis at 37°C. Capsule enlargement impaired phagocytosis by haemocytes. Incubation of the yeast in G. mellonella extracts also resulted in capsule enlargement, with the polar lipidic fraction having a prominent role in this effect. During infection, the capsule decreased in permeability. A low proportion of the cells (<5% recovered from caterpillars measured more than 30 µm and were considered giant cells. Giant cells recovered from mice were able to kill the caterpillars in a manner similar to regular cells obtained from in vivo or grown in vitro, establishing their capacity to cause disease. Our results indicate that the morphological transitions exhibited by C. neoformans in mammals also occur in a non-vertebrate host system. The similarities in morphological transitions observed in different animal hosts and in their triggers are consistent with the hypothesis that the cell body and capsular responses represent an adaptation of environmental survival strategies to pathogenesis.

Wet-bulb globe temperature index estimation using meteorological data from São Paulo State, Brazil

Science.gov (United States)

Maia, Paulo Alves; Ruas, Álvaro Cézar; Bitencourt, Daniel Pires

2015-10-01

It is well known that excessive heat exposure causes heat disorders and can lead to death in some situations. Evaluation of heat stress on workers performing indoor and outdoor activities is, nowadays, conducted worldwide by wet-bulb globe temperature (WBGT) index, which calculation parameters are dry-bulb, natural wet-bulb, and globe temperatures, which must be measured at the same time and in location where the worker is conducting his/her activities. However, for some activities performed in large outdoor areas such as those of agricultural ones, it is not feasible to measure directly those temperatures in all work periods and locations where there are workers. Taking this into account, this work aims to introduce a WBGT index estimation using atmospheric variables observed by automatic meteorological stations. In order to support our estimation method, we used, as a test-bed, data recorded in the State of São Paulo (SP), Brazil. By adding the cloudiness factor in the calculation through measurement of solar radiation, the algorithm proved to be as efficient as those mentioned in this work. It was found that this method is viable, with WBGT-estimated values obtained from meteorological data measured by stations with a distance of less than 80 km. This estimate can be used for monitoring heat stress in real time as well as to investigate heat-related disorders and agricultural work.

Lumbar facet joint fat pads: Their normal anatomy and their appearance when enlarged

International Nuclear Information System (INIS)

Taylor, J.R.; McCormick, C.C.

1991-01-01

The polar recesses, superior and inferior to lumbar facet joints, are filled by fat pads from which fat-filled synovial folds project between the articular surfaces for a distance of two to four millimetres. The intracapsular superior recess lies between the ligamentum flavum and the lamina above. The extracapsular inferior recess lies on the back of the lamina below and communicates with the joint through a hole in the inferior capsule. The intracapsular folds move freely in and out of the joint during movements. These features are demonstrated in anatomic studies using transverse sections and radiologic studies using computed tomography. In about 4% of lumbar spines examined, the intraarticular fat pads are enlarged and extend from the joint recess(es) into the middle third of one or more facet joints. The fat pads can be identified in CT scans by their radiolucency and distinguished from vacuum phenomenon by measuring their attenuation values. The cause of the intra-articular enlargement of the fat pads is unknown, but it is suggested that their extension into the middle third of the joint may be secondary to degenerative change in the motion segment with capsular laxity in the affected joint. (orig.)

Fermionic zero-norm states and enlarged supersymmetries of Type II string

International Nuclear Information System (INIS)

Lee, J.-C.

2000-01-01

We calculate the NS-R fermionic zero-norm states of the type II string spectrum. The massless and some possible massive zero-norm states are seen to be responsible for the space-time supersymmetry. The existence of other fermionic massive zero-norm states with higher spinor-tensor indices correspond to new enlarged boson-fermion symmetries of the theory at high energy. We also discuss the R-R charges and R-R zero-norm states and justify the idea that the perturbative string does not carry the massless R-R charges. (orig.)

Serum total prostate-specific antigen values in men with symptomatic prostate enlargement in Nigeria: role in clinical decision-making.

Science.gov (United States)

Nnabugwu, Ikenna I; Ugwumba, Fred O; Enivwenae, Oghenekaro A; Udeh, Emeka I; Otene, Chris O; Nnabugwu, Chinwe A

2015-01-01

Prostatic enlargement is a common cause of bladder outlet obstruction in men in Nigeria. Malignant enlargements must be differentiated from benign enlargements for adequate treatment of each patient. High serum total prostate-specific antigen (tPSA) levels suggest malignancy, but some of the biopsies done due to a serum tPSA value >4 ng/mL would be negative for malignancy because of the low specificity of tPSA for prostate cancer. This study aims to compare the histologic findings of all prostate specimens obtained from core needle biopsy, open simple prostatectomy, and transurethral resection of the prostate with the respective serum tPSA values in an attempt to decipher the role of serum tPSA in the management of these patients. The case notes of patients attended to from April 2009 to March 2012 were analyzed. Essentially, the age of the patient, findings on digital rectal examination, abdominopelvic ultrasonography report on the prostate, serum tPSA, and histology reports from biopsy or prostatectomy specimens as indicated were extracted for analysis. The relationship between age, findings on digital rectal examination, serum tPSA, abdominopelvic ultrasonography report, and histology are compared. A statistically significant relationship existed between a malignant histology and age 65 years and older, suspicious findings on digital rectal examination, suspicious ultrasonography findings, and serum tPSA >10 ng/mL, but not tPSA >4 ng/mL. In Nigerian patients with symptomatic prostate enlargement, serum tPSA should be seen as a continuum with increasing risk of prostate malignancy.

NASA WEBWORLDWIND: MULTIDIMENSIONAL VIRTUAL GLOBE FOR GEO BIG DATA VISUALIZATION

Directory of Open Access Journals (Sweden)

M. A. Brovelli

2016-06-01

Full Text Available In this paper, we presented a web application created using the NASA WebWorldWind framework. The application is capable of visualizing n-dimensional data using a Voxel model. In this case study, we handled social media data and Call Detailed Records (CDR of telecommunication networks. These were retrieved from the "BigData Challenge 2015" of Telecom Italia. We focused on the visualization process for a suitable way to show this geo-data in a 3D environment, incorporating more than three dimensions. This engenders an interactive way to browse the data in their real context and understand them quickly. Users will be able to handle several varieties of data, import their dataset using a particular data structure, and then mash them up in the WebWorldWind virtual globe. A broad range of public use this tool for diverse purposes is possible, without much experience in the field, thanks to the intuitive user-interface of this web app.