Threshold policy for global games with noisy information sharing

KAUST Repository

Mahdavifar, Hessam

2015-12-15

It is known that global games with noisy sharing of information do not admit a certain type of threshold policies [1]. Motivated by this result, we investigate the existence of threshold-type policies on global games with noisy sharing of information and show that such equilibrium strategies exist and are unique if the sharing of information happens over a sufficiently noisy environment. To show this result, we establish that if a threshold function is an equilibrium strategy, then it will be a solution to a fixed point equation. Then, we show that for a sufficiently noisy environment, the functional fixed point equation leads to a contraction mapping, and hence, its iterations converge to a unique continuous threshold policy.

Approximate method of calculation of non-equilibrium flow parameters of chemically reacting nitrogen tetroxide in the variable cross-section channels with energy exchange

International Nuclear Information System (INIS)

Bazhin, M.A.; Fedosenko, G.Eh.; Shiryaeva, N.M.; Mal'ko, M.V.

1986-01-01

It is shown that adiabatic non-equilibrium chemically reacting gas flow with energy exchange in a variable cross-section channel may be subdivided into five possible types: 1) quasi-equilibrium flow; 2) flow in the linear region of deviation from equilibrium state; 3) quasi-frozen flow; 4) flow in the linear region of deviation from frozen state; 5) non-equilibrium flow. Criteria of quasi-equilibrium and quazi-frozen flows, including factors of external action of chemically reacting gas on flow, allow to obtain simple but sufficiently reliable approximate method of calculation of flow parameters. The considered method for solving the problem of chemically reacting nitrogen tetroxide in the variable cross-section channel with energy exchange can be used for evaluation of chemical reaction kinetics on the flow parameter in the stages of axial-flow and radial-flow turbines and in another practical problems

Prevalence of Allergy to Natural Rubber Latex and Potential Cross Reacting Food in Operation Room Staff in Shiraz Hospitals -2006

Directory of Open Access Journals (Sweden)

H Nabavizade

2007-07-01

Full Text Available Introduction & Objective: Allergic reactions to natural rubber latex have increased during past 10 years especially among health care workers and patients with high exposure to latex allergens. Allergic reaction to latex is related to many diseases like occupational asthma. This study was performed to determine the prevalence of allergy to natural rubber latex and potential cross reacting food in operation room staff in Shiraz hospitals. Materials & Methods: In this cross-sectional descriptive study five hundred eighty operation room staff of ten private and state hospitals in Shiraz completed latex allergy questionnaire. They were questioned about personal history and previous history of latex sensitivity, symptoms of latex reactivity and about other allergies particularly to foods that may cross react with latex. Informed consent was obtained and skin prick testing was performed with natural rubber latex. Skin prick tests were done with three potentially cross reacting food (banana, Kiwi, and potato. The obtained data were analyzed with SPSS software and Chi-square test. Results: Among the 580 operation room workers 104 (17.9 % of participants were positive to latex skin test. We found a significant association between positive skin test to latex in operation room staff and atopy, urticaria and food allergy. Positive skin test to latex related to positive kiwi skin test (p<0.05. The prevalence did not vary by sex, age, education, surgical and non surgical glove users, history of contact dermatitis or smoking status. Conclusion: Latex allergy has a high prevalence in personnel of operation room. Evaluation of present symptom and prediction of future disease necessitate screening test in individuals at risk.

On the different "worlds" of intra-organizational knowledge management: Understanding idiosyncratic variation in MNC cross-site knowledge-sharing practices.

Science.gov (United States)

Kasper, Helmut; Lehrer, Mark; Mühlbacher, Jürgen; Müller, Barbara

2013-02-01

This qualitative field study investigated cross-site knowledge sharing in a small sample of multinational corporations in three different MNC business contexts (global, multidomestic, transnational). The results disclose heterogeneous "worlds" of MNC knowledge sharing, ultimately raising the question as to whether the whole concept of MNC knowledge sharing covers a sufficiently unitary phenomenon to be meaningful. We derive a non-exhaustive typology of MNC knowledge-sharing practices: self-organizing knowledge sharing, technocratic knowledge sharing, and best practice knowledge sharing. Despite its limitations, this typology helps to elucidate a number of issues, including the latent conflict between two disparate theories of MNC knowledge sharing, namely "sender-receiver" and "social learning" theories (Noorderhaven & Harzing, 2009). More generally, we develop the term "knowledge contextualization" to highlight the way that firm-specific organizational features pre-define which knowledge is considered to be of special relevance for intra-organizational sharing.

Beyond Our Borders? Public Resistance to Global Genomic Data Sharing.

Directory of Open Access Journals (Sweden)

Mary A Majumder

2016-11-01

Full Text Available Prospects have never seemed better for a truly global approach to science to improve human health, with leaders of national initiatives laying out their vision of a worldwide network of related projects. An extensive literature addresses obstacles to global genomic data sharing, yet a series of public polls suggests that the scientific community may be overlooking a significant barrier: potential public resistance to data sharing across national borders. In several large United States surveys, university researchers in other countries were deemed the least acceptable group of data users, and a just-completed US survey found a marked increase in privacy and security concerns related to data access by non-US researchers. Furthermore, diminished support for sharing beyond national borders is not unique to the US, although the limited data from outside the US suggest variation across countries as well as demographic groups. Possible sources of resistance include apprehension about privacy and security protections. Strategies for building public support include making the affirmative case for global data sharing, addressing privacy, security, and other legitimate concerns, and investigating public concerns in greater depth.

Prevalence of Allergy to Natural Rubber Latex and Potential Cross Reacting Food in Operation Room Staff in Shiraz Hospitals -2006

OpenAIRE

H Nabavizade; R Amin

2007-01-01

Introduction & Objective: Allergic reactions to natural rubber latex have increased during past 10 years especially among health care workers and patients with high exposure to latex allergens. Allergic reaction to latex is related to many diseases like occupational asthma. This study was performed to determine the prevalence of allergy to natural rubber latex and potential cross reacting food in operation room staff in Shiraz hospitals. Materials & Methods: In this cross-sectional descr...

Rating knowledge sharing in cross-domain collaborative filtering.

Science.gov (United States)

Li, Bin; Zhu, Xingquan; Li, Ruijiang; Zhang, Chengqi

2015-05-01

Cross-domain collaborative filtering (CF) aims to share common rating knowledge across multiple related CF domains to boost the CF performance. In this paper, we view CF domains as a 2-D site-time coordinate system, on which multiple related domains, such as similar recommender sites or successive time-slices, can share group-level rating patterns. We propose a unified framework for cross-domain CF over the site-time coordinate system by sharing group-level rating patterns and imposing user/item dependence across domains. A generative model, say ratings over site-time (ROST), which can generate and predict ratings for multiple related CF domains, is developed as the basic model for the framework. We further introduce cross-domain user/item dependence into ROST and extend it to two real-world cross-domain CF scenarios: 1) ROST (sites) for alleviating rating sparsity in the target domain, where multiple similar sites are viewed as related CF domains and some items in the target domain depend on their correspondences in the related ones; and 2) ROST (time) for modeling user-interest drift over time, where a series of time-slices are viewed as related CF domains and a user at current time-slice depends on herself in the previous time-slice. All these ROST models are instances of the proposed unified framework. The experimental results show that ROST (sites) can effectively alleviate the sparsity problem to improve rating prediction performance and ROST (time) can clearly track and visualize user-interest drift over time.

Impact of global investment processes on ukrainian share market

Directory of Open Access Journals (Sweden)

O.К. Zotsenko

2015-03-01

Full Text Available The paper investigates the effects of financial and investment processes on the Ukrainian share market. The research analyzed and estimated investment climate in Ukraine. The study highlights a comparison of the domestic share market with share markets of other countries. In terms of share capitalization of listed companies in the GDP determined that equity is the most developed in the USA and UK. Largest share markets with highest capitalization rate characterized. The regional distribution of the share market capitalization by continents are shown. The study of the dynamics of Ukrainian and global share indexes revealed that the Ukrainian share market indexes show a constant volatility and unpredictability. Correlation Ukrainian stock indexes with indexes in Europe, Russia and America is very weak, which is a very negative trend of the stock market of Ukraine. The key problems and risks of the domestic investments are defined which are consequences of downturn in the Ukrainian share market.

Shared cross-modal associations and the emergence of the lexicon

OpenAIRE

Cuskley, Christine F.

2013-01-01

This thesis centres around a sensory theory of protolanguage emergence, or STP. The STP proposes that shared biases to make associations between sensory modalities provided the basis for the emergence of a shared protolinguistic lexicon. Crucially, this lexicon would have been grounded in our perceptual systems, and thus fundamentally non-arbitrary. The foundation of such a lexicon lies in shared cross-modal associations: biases shared among language users to map properties in ...

Global bike share: What the data tells us about road safety

NARCIS (Netherlands)

Fishman, E.; Schepers, J.P.

Introduction Bike share has emerged as a rapidly growing mode of transport in over 800 cities globally, up from just a handful in the 1990s. Some analysts had forecast a rise in the number of bicycle crashes after the introduction of bike share, but empirical research on bike share safety is rare.

Global Mental Health: sharing and synthesizing knowledge for sustainable development.

Science.gov (United States)

O'Donnell, K; O'Donnell, M Lewis

2016-01-01

Global mental health (GMH) is a growing domain with an increasing capacity to positively impact the world community's efforts for sustainable development and wellbeing. Sharing and synthesizing GMH and multi-sectoral knowledge, the focus of this paper, is an important way to support these global efforts. This paper consolidates some of the most recent and relevant 'context resources' [global multi-sector (GMS) materials, emphasizing world reports on major issues] and 'core resources' (GMH materials, including newsletters, texts, conferences, training, etc.). In addition to offering a guided index of materials, it presents an orientation framework (global integration) to help make important information as accessible and useful as possible. Mental health colleagues are encouraged to stay current in GMH and global issues, to engage in the emerging agendas for sustainable development and wellbeing, and to intentionally connect and contribute across sectors. Colleagues in all sectors are encouraged to do likewise, and to take advantage of the wealth of shared and synthesized knowledge in the GMH domain, such as the materials featured in this paper.

Enabling "new" practices of renewable energy sharing : A cross-cultural approach

NARCIS (Netherlands)

Singh, A.; Van Dijk, H.W.; Romero Herrera, N.A.; Keyson, D.V.

2015-01-01

Local generation, distribution and consumption of renewable energy within neighborhood is an emerging application context for the concept of `sharing'. This position paper introduces a cross-cultural approach to enable `new' social practices of renewable energy sharing in neighborhoods. The approach

Academic Globalization: Cultureactive to Ice- the Cross-Cultural, Crossdisciplinary and Cross-Epistemological Transformation

Directory of Open Access Journals (Sweden)

Marta Szabo White

2010-12-01

Full Text Available Commensurate with the concept of Academic Globalization, coupled with the foray of Globalization, this paper underscores the cross-cultural, cross-disciplinary and cross-epistemological transformation from the first-generation Cultureactive to the second-generation InterCultural Edge [ICE]. The former is embedded in the experiential works of cross-cultural consultant. Richard Lewis and the latter is grounded in established theoretical frameworks. Both serve to underscore the impact of the Globalization Phenomenon, as manifested in and enabled by the acceleration of academic and practitioner cross-cultural activities. The contribution of this paper is the celebration of the longawaited arrival of ICE [InterCultural Edge]. While previous research streams have underscored global similarities and differences among cultures, a previous paper [19] established that cross-professional rather than cross-cultural differences are more paramount. Employing Cultureactive and the LMR framework, it was noted that business versus non-business predisposition had a more direct impact on one's individual cultural profile than did nationality. Regardless of culture, persons involved in business are characterized primarily by linear-active modes of communication, and persons involved in non-business activities typically employ more multiactive/hybrid and less linear modes of communication. The pivotal question is this: Now that we have a new and improved tool, are we in a better position to assess and predict leadership, negotiating styles, individual behaviors, etc., which are central to academic globalization and preparing global business leaders?

Buy-back and Revenue-Sharing Contracts in Global Supply Chain

Directory of Open Access Journals (Sweden)

Yang Liu

2015-09-01

Full Text Available Purpose: The main propose of this study is to investigate how exchange rate risk affects the buy-back and revenue-sharing contracts in the global supply chain, hence to improve the performance of global supply chain. Design/methodology/approach: Based on a two-echelon global supply chain, with the model equilibrium, this paper studies the difference between the buy-back contract and the revenue-sharing contract. By the transmitting of the exchange rate risk, it discusses the node-enterprises’ optimal strategies. Findings: The result shows that: (1 Both these two contracts can diminish the inefficiency caused by demand risk, but none of them can manage the exchange rate risk. (2 No matter which currency is used to settle the payment, both these two contracts will lead to the transmitting of exchange rate risk from one node-enterprise to another. (3 When the currency of the supplier’s country in the relatively appreciating, it is better to use the buy-back contract; when the currency of the supplier’s country in the relatively depreciating, the revenue-sharing contract will lead to a better result. Research limitations/implications: Though this study analyzes how the exchange rate risk affects these two contracts, it based on the assumption that node-enterprises’ goal is maximizing theirs expected profit. In fact, many firms not only focus on maximizing theirs expected profit; the risk-taking is also an important concern. For future researches, how firms’ risk-preferences affects theirs decisions in the global supply chain will be an interesting question. Also, will there be any difference if consider the node-enterprises’ utility functions instead of the expected profit. Originality/value: Existing literature about the global supply chain mainly focus on the exchange rate risk management, few of them considers the double marginalization effect caused by the demand risk. Therefore, with the exchange rate fluctuation, we discuss the

The property distance index PD predicts peptides that cross-react with IgE antibodies

Science.gov (United States)

Ivanciuc, Ovidiu; Midoro-Horiuti, Terumi; Schein, Catherine H.; Xie, Liping; Hillman, Gilbert R.; Goldblum, Randall M.; Braun, Werner

2009-01-01

Similarities in the sequence and structure of allergens can explain clinically observed cross-reactivities. Distinguishing sequences that bind IgE in patient sera can be used to identify potentially allergenic protein sequences and aid in the design of hypo-allergenic proteins. The property distance index PD, incorporated in our Structural Database of Allergenic Proteins (SDAP, http://fermi.utmb.edu/SDAP/), may identify potentially cross-reactive segments of proteins, based on their similarity to known IgE epitopes. We sought to obtain experimental validation of the PD index as a quantitative predictor of IgE cross-reactivity, by designing peptide variants with predetermined PD scores relative to three linear IgE epitopes of Jun a 1, the dominant allergen from mountain cedar pollen. For each of the three epitopes, 60 peptides were designed with increasing PD values (decreasing physicochemical similarity) to the starting sequence. The peptides synthesized on a derivatized cellulose membrane were probed with sera from patients who were allergic to Jun a 1, and the experimental data were interpreted with a PD classification method. Peptides with low PD values relative to a given epitope were more likely to bind IgE from the sera than were those with PD values larger than 6. Control sequences, with PD values between 18 and 20 to all the three epitopes, did not bind patient IgE, thus validating our procedure for identifying negative control peptides. The PD index is a statistically validated method to detect discrete regions of proteins that have a high probability of cross-reacting with IgE from allergic patients. PMID:18950868

Melanoma inhibitor of apoptosis protein (ML-IAP) specific cytotoxic T lymphocytes cross-react with an epitope from the auto-antigen SS56

DEFF Research Database (Denmark)

Baek Sørensen, Rikke; Faurschou, Mikkel; Troelsen, Lone

2009-01-01

A large proportion of melanoma patients host a spontaneous T-cell response specifically against ML-IAP-derived peptides. In this study, we describe that some ML-IAP-specific cytotoxic T cells isolated from melanoma patients cross react with an epitope from the auto-antigen SS56. SS56 is a recentl...

Energy efficient cross layer design for spectrum sharing systems

KAUST Repository

Alabbasi, AbdulRahman; Shihada, Basem

2016-01-01

We propose a cross layer design that optimizes the energy efficiency of spectrum sharing systems. The energy per good bit (EPG) is considered as an energy efficiency metric. We optimize the secondary user's transmission power and media access frame

Joint Perception of a Shared Object: a Minimalist Perceptual Crossing Experiment

Directory of Open Access Journals (Sweden)

Loïc Deschamps

2016-07-01

Full Text Available The minimalist perceptual crossing paradigm has emphasized the essential role of interpersonal dynamics on social understanding. Within the particular case of minimalist interaction, it has been argued that interpersonal processes can constitute social cognition, at least partially, which calls for a paradigm shift in social cognition studies. In this paper, we review several perceptual crossing experiments and their theoretical implications, and propose an original experiment to go beyond strictly dyadic interactions. Whereas past experiments have used objects as distractors of dyadic interaction, our experiment aims at integrating objects themselves as the goal of interpersonal coordination. We asked 24 subjects to participate in a minimalist perceptual crossing experiment where they had to decide, based on their on-line interaction in a one-dimensional digital space, which of the objects they perceived was also perceptible by their partner. The main results suggest that the mutual awareness of a shared object arises from the quality of sensorimotor coordination between the partners. Indeed, the presence of a shared object acts as a simultaneous affordance that attracts and structures individual perceptive activities, giving both partners the opportunity to co-construct a shared world where their respective actions make sense. We discuss our results by way of an enactive account of social cognition, taking the joint perception of a shared object as a first step to account for joint attention.

Identification of cross-reacting T-cell epitopes in structural and non-structural proteins of swine and pandemic H1N1 influenza A virus strains in pigs

DEFF Research Database (Denmark)

Baratelli, Massimiliano; Pedersen, Lasse Eggers; Trebbien, Ramona

2017-01-01

Heterologous protection against swine influenza viruses (SwIVs) of different lineages is an important concern for the pig industry. Cross-protection between 'avian-like' H1N1 and 2009 pandemic H1N1 lineages has been observed previously, indicating the involvement of cross-reacting T-cells. Here...

Characterization of forced response of density stratified reacting wake

Science.gov (United States)

Pawar, Samadhan A.; Sujith, Raman I.; Emerson, Benjamin; Lieuwen, Tim

2018-02-01

The hydrodynamic stability of a reacting wake depends primarily on the density ratio [i.e., ratio of unburnt gas density (ρu) to burnt gas density (ρb)] of the flow across the wake. The variation of the density ratio from high to low value, keeping ρ u / ρ b > 1 , transitions dynamical characteristics of the reacting wake from a linearly globally stable (or convectively unstable) to a globally unstable mode. In this paper, we propose a framework to analyze the effect of harmonic forcing on the deterministic and synchronization characteristics of reacting wakes. Using the recurrence quantification analysis of the forced wake response, we show that the deterministic behaviour of the reacting wake increases as the amplitude of forcing is increased. Furthermore, for different density ratios, we found that the synchronization of the top and bottom branches of the wake with the forcing signal is dependent on whether the mean frequency of the natural oscillations of the wake (fn) is lesser or greater than the frequency of external forcing (ff). We notice that the response of both branches (top and bottom) of the reacting wake to the external forcing is asymmetric and symmetric for the low and high density ratios, respectively. Furthermore, we characterize the phase-locking behaviour between the top and bottom branches of the wake for different values of density ratios. We observe that an increase in the density ratio results in a gradual decrease in the relative phase angle between the top and bottom branches of the wake, which leads to a change in the vortex shedding pattern from a sinuous (anti-phase) to a varicose (in-phase) mode of the oscillations.

ATLAS Global Shares Implementation in the PanDA Workload Management System

CERN Document Server

Barreiro Megino, Fernando Harald; The ATLAS collaboration

2018-01-01

PanDA (Production and Distributed Analysis) is the workload management system for ATLAS across the Worldwide LHC Computing Grid. While analysis tasks are submitted to PanDA by over a thousand users following personal schedules (e.g. PhD or conference deadlines), production campaigns are scheduled by a central Physics Coordination group based on the organization’s calendar. The Physics Coordination group needs to allocate the amount of Grid resources dedicated to each activity, in order to manage sharing of CPU resources among various parallel campaigns and to make sure that results can be achieved in time for important deadlines. While dynamic and static shares on batch systems have been around for a long time, we are trying to move away from local resource partitioning and manage shares at a global level in the PanDA system. The global solution is not straightforward, given different requirements of the activities (number of cores, memory, I/O and CPU intensity), the heterogeneity of Grid resources (site/H...

Academic Globalization: Universality of Cross-Cultural And Cross-Disciplinary LMR Perspectives

Directory of Open Access Journals (Sweden)

Marta Szabo White

2010-10-01

Full Text Available The contribution of this paper suggests that previous research underscoring cross-cultural differences may be misleading, when in fact it is cross-professional rather than cross-cultural differences that should be emphasized. Employing the LMR framework, this paper concludes that business or non-business predisposition has a more direct impact on one's individual cultural profile than does nationality. Regardless of culture, persons involved in business are characterized primarily by linear-active modes of communication, and persons not involved in business typically employ less linear and more multi-active/hybrid modes of communication. The linkages among individual characteristics, communication styles, work behaviors, and the extent to which the LMR constructs can facilitate and predict leadership, negotiating styles, individual behaviors, etc. are central to academic globalization and preparing global business leaders.

Effort sharing in ambitious, global climate change mitigation scenarios

International Nuclear Information System (INIS)

Ekholm, Tommi; Soimakallio, Sampo; Moltmann, Sara; Hoehne, Niklas; Syri, Sanna; Savolainen, Ilkka

2010-01-01

The post-2012 climate policy framework needs a global commitment to deep greenhouse gas emission cuts. This paper analyzes reaching ambitious emission targets up to 2050, either -10% or -50% from 1990 levels, and how the economic burden from mitigation efforts could be equitably shared between countries. The scenarios indicate a large low-cost mitigation potential in electricity and industry, while reaching low emission levels in international transportation and agricultural emissions might prove difficult. The two effort sharing approaches, Triptych and Multistage, were compared in terms of equitability and coherence. Both approaches produced an equitable cost distribution between countries, with least developed countries having negative or low costs and more developed countries having higher costs. There is, however, no definitive solution on how the costs should be balanced equitably between countries. Triptych seems to be yet more coherent than other approaches, as it can better accommodate national circumstances. Last, challenges and possible hindrances to effective mitigation and equitable effort sharing are presented. The findings underline the significance of assumptions behind effort sharing on mitigation potentials and current emissions, the challenge of sharing the effort with uncertain future allowance prices and how inefficient markets might undermine the efficiency of a cap-and-trade system.

Effort sharing in ambitious, global climate change mitigation scenarios

Energy Technology Data Exchange (ETDEWEB)

Ekholm, Tommi [TKK Helsinki University of Technology, Espoo (Finland); Soimakallio, Sampo; Syri, Sanna; Savolainen, Ilkka [VTT Technical Research Centre of Finland, P.O. Box 1000, FIN-02044 VTT (Finland); Moltmann, Sara; Hoehne, Niklas [Ecofys Germany GmbH, Cologne (Germany)

2010-04-15

The post-2012 climate policy framework needs a global commitment to deep greenhouse gas emission cuts. This paper analyzes reaching ambitious emission targets up to 2050, either or from 1990 levels, and how the economic burden from mitigation efforts could be equitably shared between countries. The scenarios indicate a large low-cost mitigation potential in electricity and industry, while reaching low emission levels in international transportation and agricultural emissions might prove difficult. The two effort sharing approaches, Triptych and Multistage, were compared in terms of equitability and coherence. Both approaches produced an equitable cost distribution between countries, with least developed countries having negative or low costs and more developed countries having higher costs. There is, however, no definitive solution on how the costs should be balanced equitably between countries. Triptych seems to be yet more coherent than other approaches, as it can better accommodate national circumstances. Last, challenges and possible hindrances to effective mitigation and equitable effort sharing are presented. The findings underline the significance of assumptions behind effort sharing on mitigation potentials and current emissions, the challenge of sharing the effort with uncertain future allowance prices and how inefficient markets might undermine the efficiency of a cap-and-trade system. (author)

AIDS: Ushering in a new era of shared responsibility for global health

Directory of Open Access Journals (Sweden)

Buse Kent

2012-07-01

Full Text Available Abstract For the first time since AIDS erupted as worldwide emergency, global leaders, the scientific community, activists and people living with HIV are venturing to speak about the end to the pandemic. Signs of hope abound: over 8 million people are receiving life-saving treatment, the number of new infections is on significant decline, the remarkable evidence of treatment’s impact on preventing new infections and the aspiration of zero new HIV infections among children is firmly within grasp. This progress, won by people living with HIV and countries with support from partners such as the US programme PEPFAR, the Clinton Health Access Initiative and untold more, embodies global solidarity to bring about an AIDS-free generation. Shared responsibility and global solidarity represents a normative ideal to which both individual stakeholders and the global community must subscribe and embrace if our collective vision of an AIDS-free world is to be realised. The idea of shared responsibility and global solidarity needs to goes further than raising and investing resources and extend to the level of control countries take of their AIDS response. This editorial explores five areas that require further attention.

Cross-platform development with React Native

OpenAIRE

Beshir, Aymen

2016-01-01

In this project a mobile application for dog owners is built, whichallows dog owners to create their own profile. The customer is a dogwhisperer with the aspiration to create a platform for dog ownerswhere they can share and access articles and experiences and structuretheir dog's life.This mobile application is built for both Android and iOS. Buildingnative mobile applications has never been easier given the manyresources and frameworks available for developers. But since theframeworks are o...

The inositol-1,2-cyclic phosphate moiety of the cross-reacting determinant, carbohydrate chains, and proteinaceous components are all responsible for the cross-reactivity of trypanosome variant surface glycoproteins.

Science.gov (United States)

Escalona, José L; Uzcanga, Graciela L; Carrasquel, Liomary M; Bubis, José

2018-01-24

Salivarian trypanosomes evade the host immune system by continually swapping their protective variant surface glycoprotein (VSG) coat. Given that VSGs from various trypanosome stocks exhibited cross-reactivity (Camargo et al., Vet. Parasitol. 207, 17-33, 2015), we analyzed here which components are the antigenic determinants for this cross-reaction. Soluble forms of VSGs were purified from four Venezuelan animal trypanosome isolates: TeAp-N/D1, TeAp-ElFrio01, TeAp-Mantecal01, and TeGu-Terecay323. By using the VSG soluble form from TeAp-N/D1, we found that neither the inositol-1,2-cyclic phosphate moiety of the cross-reacting determinant nor the carbohydrate chains were exclusively responsible for its cross-reactivity. Then, all four purified glycoproteins were digested with papain and the resulting peptides were separated by high-performance liquid chromatography. Dot blot evaluation of the fractions using sera from trypanosome-infected animals yielded peptides that possessed cross-reaction activity, demonstrating for the first time that proteinaceous epitopes are also responsible for the cross-reactivity of trypanosome VSGs.

Establishing Shared Knowledge about Globalization in Asia and the Arctic

DEFF Research Database (Denmark)

Bertelsen, Rasmus Gjedssø; Graczyk, Piotr

2016-01-01

We discuss the role of knowledge in relations between Arctic communities and Asia (the Arctic Council observer states: China, India, Japan, Singapore, South Korea). We argue that mutual and shared knowledge between Arctic communities and Asia is necessary for local benefits and comprehensively su...... sustainable development for Arctic communities under globalization....

The effect of HLA mismatches, shared cross-reactive antigen groups, and shared HLA-DR antigens on the outcome after pediatric liver transplantation

NARCIS (Netherlands)

Sieders, E; Hepkema, BG; Peeters, PMJG; Ten Vergert, EM; De Jong, KP; Porte, RJ; Bijleveld, CMA; van den Berg, AP; Lems, SPM; Gouw, ASH; Slooff, MJH

2005-01-01

The aim of this study was to analyze the effect of human leukocyte antigen (HLA) class I and HLA-DR mismatching, sharing cross-reactive antigen groups (CREGs), and sharing HLA-DR antigens on the outcome after pediatric liver transplantation. Outcome parameters were graft survival, acute rejection,

Comparison of Mixing Calculations for Reacting and Non-Reacting Flows in a Cylindrical Duct

Science.gov (United States)

Oechsle, V. L.; Mongia, H. C.; Holdeman, J. D.

1994-01-01

A production 3-D elliptic flow code has been used to calculate non-reacting and reacting flow fields in an experimental mixing section relevant to a rich burn/quick mix/lean burn (RQL) combustion system. A number of test cases have been run to assess the effects of the variation in the number of orifices, mass flow ratio, and rich-zone equivalence ratio on the flow field and mixing rates. The calculated normalized temperature profiles for the non-reacting flow field agree qualitatively well with the normalized conserved variable isopleths for the reacting flow field indicating that non-reacting mixing experiments are appropriate for screening and ranking potential rapid mixing concepts. For a given set of jet momentum-flux ratio, mass flow ratio, and density ratio (J, MR, and DR), the reacting flow calculations show a reduced level of mixing compared to the non-reacting cases. In addition, the rich-zone equivalence ratio has noticeable effect on the mixing flow characteristics for reacting flows.

Global bike share: What the data tells us about road safety.

Science.gov (United States)

Fishman, Elliot; Schepers, Paul

2016-02-01

Bike share has emerged as a rapidly growing mode of transport in over 800 cities globally, up from just a handful in the 1990s. Some analysts had forecast a rise in the number of bicycle crashes after the introduction of bike share, but empirical research on bike share safety is rare. The goal of this study is to examine the impact of bike share programs on cycling safety. The paper has two substudies. Study 1 was a secondary analysis of longitudinal hospital injury data from the Graves et al. (2014) study. It compared cycling safety in cities that introduced bike share programs with cities that did not. Study 2 combined ridership data with crash data of selected North American and European cities to compare bike share users to other cyclists. Study 1 indicated that the introduction of a bike share system was associated with a reduction in cycling injury risk. Study 2 found that bike share users were less likely than other cyclists to sustain fatal or severe injuries. On a per kilometer basis, bike share is associated with decreased risk of both fatal and non-fatal bicycle crashes when compared to private bike riding. The results of this study suggest that concerns of decreased levels of cycling safety are unjustified and should not prevent decision makers from introducing public bike share schemes, especially if combined with other safety measures like traffic calming. Copyright © 2015 Elsevier Ltd and National Safety Council. All rights reserved.

Global reinforcement training of CrossNets

Science.gov (United States)

Ma, Xiaolong

2007-10-01

Hybrid "CMOL" integrated circuits, incorporating advanced CMOS devices for neural cell bodies, nanowires as axons and dendrites, and latching switches as synapses, may be used for the hardware implementation of extremely dense (107 cells and 1012 synapses per cm2) neuromorphic networks, operating up to 10 6 times faster than their biological prototypes. We are exploring several "Cross- Net" architectures that accommodate the limitations imposed by CMOL hardware and should allow effective training of the networks without a direct external access to individual synapses. Our studies have show that CrossNets based on simple (two-terminal) crosspoint devices can work well in at least two modes: as Hop-field networks for associative memory and multilayer perceptrons for classification tasks. For more intelligent tasks (such as robot motion control or complex games), which do not have "examples" for supervised learning, more advanced training methods such as the global reinforcement learning are necessary. For application of global reinforcement training algorithms to CrossNets, we have extended Williams's REINFORCE learning principle to a more general framework and derived several learning rules that are more suitable for CrossNet hardware implementation. The results of numerical experiments have shown that these new learning rules can work well for both classification tasks and reinforcement tasks such as the cartpole balancing control problem. Some limitations imposed by the CMOL hardware need to be carefully addressed for the the successful application of in situ reinforcement training to CrossNets.

Cross-Jurisdictional Resource Sharing in Changing Public Health Landscape: Contributory Factors and Theoretical Explanations.

Science.gov (United States)

Shah, Gulzar H; Badana, Adrian N S; Robb, Claire; Livingood, William C

2016-01-01

Local health departments (LHDs) are striving to meet public health needs within their jurisdictions, amidst fiscal restraints and complex dynamic environment. Resource sharing across jurisdictions is a critical opportunity for LHDs to continue to enhance effectiveness and increase efficiency. This research examines the extent of cross-jurisdictional resource sharing among LHDs, the programmatic areas and organizational functions for which LHDs share resources, and LHD characteristics associated with resource sharing. Data from the National Association of County & City Health Officials' 2013 National Profile of LHDs were used. Descriptive statistics and multinomial logistic regression were performed for the 5 implementation-oriented outcome variables of interest, with 3 levels of implementation. More than 54% of LHDs shared resources such as funding, staff, or equipment with 1 or more other LHDs on a continuous, recurring basis. Results from the multinomial regression analysis indicate that economies of scale (population size and metropolitan status) had significant positive influences (at P ≤ .05) on resource sharing. Engagement in accreditation, community health assessment, community health improvement planning, quality improvement, and use of the Community Guide were associated with lower levels of engagement in resource sharing. Doctoral degree of the top executive and having 1 or more local boards of health carried a positive influence on resource sharing. Cross-jurisdictional resource sharing is a viable and commonly used process to overcome the challenges of new and emerging public health problems within the constraints of restricted budgets. LHDs, particularly smaller LHDs with limited resources, should consider increased resource sharing to address emerging challenges.

Images crossing borders: image and workflow sharing on multiple levels.

Science.gov (United States)

Ross, Peeter; Pohjonen, Hanna

2011-04-01

Digitalisation of medical data makes it possible to share images and workflows between related parties. In addition to linear data flow where healthcare professionals or patients are the information carriers, a new type of matrix of many-to-many connections is emerging. Implementation of shared workflow brings challenges of interoperability and legal clarity. Sharing images or workflows can be implemented on different levels with different challenges: inside the organisation, between organisations, across country borders, or between healthcare institutions and citizens. Interoperability issues vary according to the level of sharing and are either technical or semantic, including language. Legal uncertainty increases when crossing national borders. Teleradiology is regulated by multiple European Union (EU) directives and legal documents, which makes interpretation of the legal system complex. To achieve wider use of eHealth and teleradiology several strategic documents were published recently by the EU. Despite EU activities, responsibility for organising, providing and funding healthcare systems remains with the Member States. Therefore, the implementation of new solutions requires strong co-operation between radiologists, societies of radiology, healthcare administrators, politicians and relevant EU authorities. The aim of this article is to describe different dimensions of image and workflow sharing and to analyse legal acts concerning teleradiology in the EU.

A systematic review of knowledge sharing challenges and practices in global software development

DEFF Research Database (Denmark)

Zahedi, Mansooreh; Shahin, Mojtaba; Babar, Muhammad Ali

2016-01-01

the data extracted from the reviewed primary studies. Results: Our findings revealed that knowledge sharing challenges and practices in GSD could be classi- fied in 6 main themes: management, team structure, work processes/practices, team cognition, social attributes and technology. In regard to contextual......Context: Global Software Development (GSD) presents significant challenges to share and understand knowledge required for developing software. Organizations are expected to implement appropriate practices to address knowledge-sharing challenges in GSD. With the growing literature on GSD and its...... and practices fall under the theme of “work practices”. (c) The technology related knowledge-sharing challenges are the least reported; we discussed the available technologies for sup- porting knowledge sharing needs in GSD. (d) The organizational contextual information is missing from a large number of studies...

Sharing Data to Build a Medical Information Commons: From Bermuda to the Global Alliance.

Science.gov (United States)

Cook-Deegan, Robert; Ankeny, Rachel A; Maxson Jones, Kathryn

2017-08-31

The Human Genome Project modeled its open science ethos on nematode biology, most famously through daily release of DNA sequence data based on the 1996 Bermuda Principles. That open science philosophy persists, but daily, unfettered release of data has had to adapt to constraints occasioned by the use of data from individual people, broader use of data not only by scientists but also by clinicians and individuals, the global reach of genomic applications and diverse national privacy and research ethics laws, and the rising prominence of a diverse commercial genomics sector. The Global Alliance for Genomics and Health was established to enable the data sharing that is essential for making meaning of genomic variation. Data-sharing policies and practices will continue to evolve as researchers, health professionals, and individuals strive to construct a global medical and scientific information commons.

Cross-Cultural Understanding for Global Sustainability: Messages and Meanings from Asian Cultural Landscapes

Science.gov (United States)

Singh, R.

2013-11-01

Concept of 'multifunctionality' of cultural landscapes is a reflection of imbued meaning and aesthetics inherent there and also human manifestation of this spirit through existence and aliveness by human creation, love and continuance in various cultures and traditions. This sense helps envisioning landscapes that cross urban-rural divides in sustainable and an integrated way - characterised by wholeness and ecospirituality that developed in the cultural history of landscape sustainability. That is how, the idea of 'wholeness' (cosmality) is transformed into 'holiness' (sacrality) ― evolved and represented with sacred ecology and visualised through the cosmic frames of sacredscapes in Asian region that survived there as part of lifeworld. Understanding, feeling, living with, practicing and passing on these inherent meanings and aesthetics provide peace, solace and deeper feelings to human mind which are the ethereal breathe of sustainability. The rethinking should be based on the foundational value ― the reasoning that underlies the ethical sense of deeper understanding of Man-Nature Interrelatedness, the basic philosophy of coexistence ― referred in different cultures in their own ways, like multicultural co-living ('Old-comer') in Korea, harmonious coexistence (tabunka kyosei) in Japan, harmonious society (xiaokang) in China, wahi tapu (sacred places) in Maori's New Zealand, global family (vasudhaiva kutumbakam) in Indian thought, and also African humanism (ubuntu) in South Africa. Think universally, see globally, behave regionally, act locally but insightfully; this is an appeal for shared wisdom for global sustainability in making our cultural landscapes mosaic of happy, peaceful and sustainable places crossing all the borders and transitions, especially interwoven links among Korea, Japan, China, and India.

Evidence for globally shared, cross-reacting polymorphic epitopes in the pregnancy-associated malaria vaccine candidate VAR2CSA

DEFF Research Database (Denmark)

Avril, Marion; Kulasekara, Bridget R; Gose, Severin O

2008-01-01

Pregnancy-associated malaria (PAM) is characterized by the placental sequestration of Plasmodium falciparum-infected erythrocytes (IEs) with the ability to bind to chondroitin sulfate A (CSA). VAR2CSA is a leading candidate for a pregnancy malaria vaccine, but its large size ( approximately 350 k...

Cross-border entrepreneurship in a global world

DEFF Research Database (Denmark)

Emontspool, Julie; Servais, Per

2017-01-01

This paper shows that international entrepreneurship and immigrant entrepreneurship increasingly intersect in a global world. Both research streams address cross-border entrepreneurial activity in parallel to each other. International entrepreneurship focuses on outgoing entrepreneurial activity......, while immigrant entrepreneurship mainly considers incoming entrepreneurial activity. This paper critically discusses such a dichotomy, highlighting how differentiating immigrant entrepreneurs and international entrepreneurs perpetuates orientalist assumptions about cross-border business activity....... Focusing on a entrepreneurship as behaviour, the paper proposes an alternative perspective to cross-border entrepreneurship, discussing cross-border opportunity identification and exploitation between an entrepreneur’s country of residence and a foreign country. This perspective provides a number...

Optimal Cross-Layer Design for Energy Efficient D2D Sharing Systems

KAUST Repository

Alabbasi, Abdulrahman

2016-11-23

In this paper, we propose a cross-layer design, which optimizes the energy efficiency of a potential future 5G spectrum-sharing environment, in two sharing scenarios. In the first scenario, underlying sharing is considered. We propose and minimize a modified energy per good bit (MEPG) metric, with respect to the spectrum sharing user’s transmission power and media access frame length. The cellular users, legacy users, are protected by an outage probability constraint. To optimize the non-convex targeted problem, we utilize the generalized convexity theory and verify the problem’s strictly pseudoconvex structure. We also derive analytical expressions of the optimal resources. In the second scenario, we minimize a generalized MEPG function while considering a probabilistic activity of cellular users and its impact on the MEPG performance of the spectrum sharing users. Finally, we derive the associated optimal resource allocation of this problem. Selected numerical results show the improvement of the proposed system compared with other systems.

REAC/TS Radiation Accident Registry: An Overview

Energy Technology Data Exchange (ETDEWEB)

Doran M. Christensen, DO, REAC/TS Associate Director and Staff Physician Becky Murdock, REAC/TS Registry and Health Physics Technician

2012-12-12

Over the past four years, REAC/TS has presented a number of case reports from its Radiation Accident Registry. Victims of radiological or nuclear incidents must meet certain dose criteria for an incident to be categorized as an “accident” and be included in the registry. Although the greatest numbers of “accidents” in the United States that have been entered into the registry involve radiation devices, the greater percentage of serious accidents have involved sealed sources of one kind or another. But if one looks at the kinds of accident scenarios that have resulted in extreme consequence, i.e., death, the greater share of deaths has occurred in medical settings.

Studies on antigenic cross-reactivity of Trichuris ovis with host mucosal antigens in goat

OpenAIRE

Gautam Patra; Seikh Sahanawaz Alam; Sonjoy Kumar Borthakur; Hridayesh Prasad

2015-01-01

Objective: To ascertain whether immunodominant antigens of Trichuris ovis might share and cross react with host molecule. Methods: Two crude protein preparations from anterior and posterior parts of Trichuris ovis were characterized along with host mucosal antigen by double immunodiffusion, sodium dodecyl sulfate-polyacrylamide gel electrophoresis and western blotting technique. Conventional scanning electron microscopy was performed as per standard procedure. Results: Sharp...

Organized Communities as a Hybrid Form of Data Sharing: Experiences from the Global STEP Project

Directory of Open Access Journals (Sweden)

Isabell Stamm

2018-01-01

Full Text Available With this article, I explore a new way of how social scientists can share primary qualitative data with each other. More specifically, I examine organized research communities, which are small membership groups of scholars. This hybrid form of data sharing is positioned between informal sharing through collaboration and institutionalized sharing through accessing research archives. Using the global "Successful Transgenerational Entrepreneurship Practices" (STEP project as an example, I draw attention to the pragmatic practices of data sharing in such communities. Through ongoing negotiations, organized communities can, at least temporarily, put forward sharing policies and create a culture of data sharing that elevates the re-use of qualitative data while being mindful of the data's intersubjective and processual character.

Cross-Layer Design in Dynamic Spectrum Sharing Systems

Directory of Open Access Journals (Sweden)

Shadmand A

2010-01-01

Full Text Available We consider a dynamic spectrum sharing system consisting of a primary user, whose licensed spectrum is allowed to be accessed by a secondary user as long as it does not violate the prescribed interference limit inflicted on the primary user. Assuming the Nakagami- block-fading environment, we aim at maximizing the performance of secondary user's link in terms of average spectral efficiency (ASE and error performance under the specified packet error rate (PER and average interference limit constraints. To this end, we employ a cross-layer design policy which combines adaptive power and coded discrete M-QAM modulation scheme at the physical layer with a truncated automatic repeat request (ARQ protocol at the data link layer, and simultaneously satisfies the aforementioned constraints. Numerical results affirm that the secondary link of spectrum sharing system combining ARQ with adaptive modulation and coding (AMC achieves significant gain in ASE depending on the maximum number of retransmissions initiated by the ARQ protocol. The results further indicate that the ARQ protocol essentially improves the packet loss rate performance of the secondary link.

Partial characterization of the cross-reacting determinant, a carbohydrate epitope shared by decay accelerating factor and the variant surface glycoprotein of the African Trypanosoma brucei.

Science.gov (United States)

Shak, S; Davitz, M A; Wolinsky, M L; Nussenzweig, V; Turner, M J; Gurnett, A

1988-03-15

The variant surface glycoprotein (VSG) of the African trypanosome is anchored in the cell membrane by a complex glycan attached to phosphatidylinositol. The carboxyl terminal portion of VSG contains a cryptic carbohydrate epitope, the cross-reacting determinant (CRD), that is revealed only after removal of the diacylglycerol by phosphatidylinositol-specific phospholipase C (PIPLC) or VSG lipase. Recently, we have shown that after hydrolysis by PIPLC, decay-accelerating factor (DAF)--a mammalian phosphatidylinositol-anchored protein--also contains the CRD epitope. Using a two site immunoradiometric assay in which the capturing antibody is a monoclonal antibody to DAF and the revealing antibody is anti-CRD, we now show that sugar phosphates significantly inhibited the binding of anti-CRD antibody to DAF released by PIPLC. DL-myo-inositol 1,2-cyclic phosphate was the most potent inhibitor of binding (IC50 less than 10(-8) M). Other sugar phosphates, such as alpha-D-glucose-1-phosphate, which also possess adjacent hydroxyl and phosphate moieties in cis also inhibited binding at low concentrations (IC50 = 10(-5) to 10(-4) M). In contrast, sugar phosphates which do not possess adjacent hydroxyl and phosphate moieties in cis and simple sugars weakly inhibited binding (IC50 greater than 10(-3) M). These results suggest that myo-inositol 1,2-cyclic phosphate contributes significantly to the epitope recognized by the anti-CRD antibody and is consistent with analysis of the carboxyl terminus of VSG, which also suggested the presence of the cyclic inositol phosphate. In light of the recent findings that human serum contains a glycan-phosphatidyl-inositol-specific phospholipase D, which converts DAF from a hydrophobic to a hydrophilic form lacking the CRD, the observation that the phosphate is crucial for expression of the epitope may be relevant in understanding the origin of CRD-negative DAF in urine and plasma.

The molecular basis of the antigenic cross-reactivity between measles and cowpea mosaic viruses

International Nuclear Information System (INIS)

Olszewska, Wieslawa; Steward, Michael W.

2003-01-01

Two nonrelated viruses, cowpea mosaic virus (wtCPMV) and measles virus (MV), were found to induce cross-reactive antibodies. The nature of this cross-reactivity was studied and results are presented here demonstrating that antiserum raised against wtCPMV reacted with peptide from the fusion (F) protein of MV. Furthermore, the F protein of MV was shown to share an identical conformational B cell epitope with the small subunit of CPMV coat protein. Passive transfer of anti-wtCPMV antibodies into BALB/c mice conferred partial protection against measles virus induced encephalitis. The results are discussed in the context of cross-protection

Joint Perception of a Shared Object: A Minimalist Perceptual Crossing Experiment.

Science.gov (United States)

Deschamps, Loïc; Lenay, Charles; Rovira, Katia; Le Bihan, Gabrielle; Aubert, Dominique

2016-01-01

The minimalist perceptual crossing paradigm has emphasized the essential role of interpersonal dynamics on social understanding. Within the particular case of minimalist interaction, it has been argued that interpersonal processes can constitute social cognition, at least partially, which calls for a paradigm shift in social cognition studies. In this paper, we review several perceptual crossing experiments and their theoretical implications, and propose an original experiment to go beyond strictly dyadic interactions. Whereas past experiments have used objects as distracters of dyadic interaction, our experiment aims at integrating objects themselves as the goal of interpersonal coordination. We asked 24 subjects to participate in a minimalist perceptual crossing experiment where they had to decide, based on their on-line interaction in a one-dimensional digital space, which of the objects they perceived was also perceptible by their partner. The main results suggest that the mutual awareness of a shared object (SO) arises from the quality of sensorimotor coordination between the partners. Indeed, the presence of a SO acts as a simultaneous affordance that attracts and structures individual perceptive activities, giving both partners the opportunity to co-construct a shared world where their respective actions make sense. We discuss our results by way of an enactive account of social cognition, taking the joint perception of a SO as a first step to account for joint attention.

77 FR 58412 - Meeting of the Global Justice Information Sharing Initiative Federal Advisory Committee

Science.gov (United States)

2012-09-20

... support of the Administration's justice priorities. The GAC will guide and monitor the development of the Global information sharing concept. It will advise the Assistant Attorney General, OJP; the Attorney...

Global Liquidity and Drivers of Cross-Border Bank Flows

NARCIS (Netherlands)

Cerutti, E.; Claessens, S.; Ratnovski, L.

2014-01-01

This paper provides a definition of global liquidity consistent with its meaning as the "ease of financing" in international financial markets. Using a longer time series and broader sample of countries than in previous studies, it identifies global factors driving cross-border bank flows, alongside

A comparability analysis of global burden sharing GHG reduction scenarios

International Nuclear Information System (INIS)

Ciscar, Juan-Carlos; Saveyn, Bert; Soria, Antonio; Szabo, Laszlo; Van Regemorter, Denise; Van Ierland, Tom

2013-01-01

The distribution of the mitigation burden across countries is a key issue regarding the post-2012 global climate policies. This article explores the economic implications of alternative allocation rules, an assessment made in the run-up to the COP15 in Copenhagen (December 2009). We analyse the comparability of the allocations across countries based on four single indicators: GDP per capita, GHG emissions per GDP, GHG emission trends in the recent past, and population growth. The multi-sectoral computable general equilibrium model of the global economy, GEM-E3, is used for that purpose. Further, the article also compares a perfect carbon market without transaction costs with the case of a gradually developing carbon market, i.e. a carbon market with (gradually diminishing) transaction costs. - Highlights: ► Burden sharing of global mitigation efforts should consider equity and efficiency. ► The comparability of allocations across countries is based on four indicators. ► The four indicators are GDP/capita, GHG/GDP, population growth, and GHG trend. ► Any possible agreement on effort comparability needs a combination of indicators. ► We analyse the role played by the degree of flexibility in global carbon trading

Enhancing Cross-Cultural Competence in Multicultural Teacher Education: Transformation in Global Learning

Science.gov (United States)

Seeberg, Vilma; Minick, Theresa

2012-01-01

Teacher education needs to engage teacher candidates in developing cross-cultural competence so that they may be able to transmit global learning to their future students. This study theorizes cross-cultural competence (CCC) from the perspectives of multicultural and global education. During a four-year project at a mid-western US university,…

76 FR 13226 - Meeting of the Department of Justice Global Justice Information Sharing Initiative Federal...

Science.gov (United States)

2011-03-10

... coordination of national policy, practices, and technical solutions in support of the Administration's justice priorities. The GAC will guide and monitor the development of the Global information sharing concept. It will...

From individual innovation to global impact: the Global Cooperation on Assistive Technology (GATE) innovation snapshot as a method for sharing and scaling.

Science.gov (United States)

Layton, Natasha; Murphy, Caitlin; Bell, Diane

2018-05-09

Assistive technology (AT) is an essential facilitator of independence and participation, both for people living with the effects of disability and/or non-communicable disease, as well as people aging with resultant functional decline. The World Health Organization (WHO) recognizes the substantial gap between the need for and provision of AT and is leading change through the Global Cooperation on Assistive Technology (GATE) initiative. Showcasing innovations gathered from 92 global researchers, innovators, users and educators of AT through the WHO GREAT Summit, this article provides an analysis of ideas and actions on a range of dimensions in order to provide a global overview of AT innovation. The accessible method used to capture and showcase this data is presented and critiqued, concluding that "innovation snapshots" are a rapid and concise strategy to capture and showcase AT innovation and to foster global collaboration. Implications for Rehabilitation Focal tools such as ePosters with uniform data requirements enable the rapid sharing of information. A diversity of innovative practices are occurring globally in the areas of AT Products, Policy, Provision, People and Personnel. The method offered for Innovation Snapshots had substantial uptake and is a feasible means to capture data across a range of stakeholders. Meeting accessibility criteria is an emerging competency in the AT community. Substantial areas of common interest exist across regions and globally in the AT community, demonstrating the effectiveness of information sharing platforms such as GATE and supporting the idea of regional forums and networks.

Korean Social Studies Preservice Teachers' Cross-Cultural Learning and Global Perspective Development: Crossing Borders between Korea and the United States

Science.gov (United States)

Choi, Yoonjung; Choi, Minsik

2012-01-01

This study investigated the influence of cross-cultural learning experiences on Korean preservice social studies teachers' global perspectives development. Social studies preservice teachers in a large woman's university in Korea participated in a cross-cultural learning course, which focused on critical understanding of globalization and global…

Matérn-based nonstationary cross-covariance models for global processes

KAUST Repository

Jun, Mikyoung

2014-07-01

Many spatial processes in environmental applications, such as climate variables and climate model errors on a global scale, exhibit complex nonstationary dependence structure, in not only their marginal covariance but also their cross-covariance. Flexible cross-covariance models for processes on a global scale are critical for an accurate description of each spatial process as well as the cross-dependences between them and also for improved predictions. We propose various ways to produce cross-covariance models, based on the Matérn covariance model class, that are suitable for describing prominent nonstationary characteristics of the global processes. In particular, we seek nonstationary versions of Matérn covariance models whose smoothness parameters vary over space, coupled with a differential operators approach for modeling large-scale nonstationarity. We compare their performance to the performance of some existing models in terms of the aic and spatial predictions in two applications: joint modeling of surface temperature and precipitation, and joint modeling of errors in climate model ensembles. © 2014 Elsevier Inc.

A Case Study of the Global Group for Sharing Knowledge and Efforts in Human Resources within the Nuclear Industry

International Nuclear Information System (INIS)

Thomas, C.

2016-01-01

Full text: One of the main conclusions from the IAEA’s HRD Conference in 2014 was that people and organisations in the global nuclear industry could cooperate more in sharing information and efforts. This was an inspiring conclusion, and there seemed an especially great opportunity for such sharing of information and efforts related to the attraction, recruitment, development and retention of people within the nuclear workforce. Founding members include people from the IAEA, WNA, WANO, EDF and OPG amongst others, the global working group for Human Resource matters aimed at “Building and Sustaining a Competent Nuclear Workforce” was established. This global working group is free to join and is open to anyone concerned with Building and Sustaining a Competent NuclearWorkforce. The objectives of the group are to share useful information, find others with similar objectives to cooperate with, ask questions, share opinions and crucially to avoid unnecessary duplication of efforts. The group already has 160 members from more than 15 countries and is currently hosted as a group on the LinkedIn website. The vision for the group is that it will become an invaluable resource for people across the world in the nuclear industry for sharing information and efforts. (author

The effect of corporate sustainability information on share returns: analysis of companies included in the Global Ranking 100 [doi: 10.21529/RECADM.2017010

Directory of Open Access Journals (Sweden)

Nathállya Etyenne Figueira Silva

2017-10-01

Full Text Available This study aimed to analyze the effect of corporate returns after the disclosure of inclusion in the Global 100 ranking. For this purpose, the methodology of the Study of Events was used, based on the hypothesis of a semi-strong efficient market. The Global 100 rankings considered in this study were the ones released over 12 years, from 2005 to 2016. The survey sample composed of the shares of the companies that had data on the date of their inclusion, and thus consisting of 266 shares. The variable used was daily quotations of companies' shares during the estimation period (160 days and event window (21 days and the market indices of the countries in which the share was quoted, collected in the Thomson Reuters Database®. The results showed that the release of the Global 100 ranking did not cause significant positive or negative effect on the cumulative abnormal returns (CARs of the shares of listed companies.   Keywords Global 100; Corporate social responsibility; Sustainability; Financial performance.

Sharing Economy vs Sharing Cultures? Designing for social, economic and environmental good

Directory of Open Access Journals (Sweden)

Ann Light

2015-05-01

Full Text Available This paper explores the story behind a crowdfunding service as an example of sharing technology. Research in a small neighborhood of London showed how locally-developed initiatives can differ in tone, scale, ambition and practice to those getting attention in the so-called sharing economy. In local accounts, we see an emphasis on organizing together to create shared spaces for collaborative use of resources and joint ownership of projects and places. Whereas, many global business models feature significant elements of renting, leasing and hiring and focus only on resource management, sometimes at the expense of community growth. The service we discuss is based in the area we studied and has a collective model of sharing, but hopes to be part of the new global movement. We use this hybridity to problematize issues of culture, place and scalability in developing sharing resources and addressing sustainability concerns. We relate this to the motivation, rhetoric and design choices of other local sharing enterprises and other global sharing economy initiatives, arguing, in conclusion, that there is no sharing economy, but a variety of new cultures being fostered.

Globalization and economic cooperation

Directory of Open Access Journals (Sweden)

Javier Divar

2006-12-01

Full Text Available Economic globalization is nothing, really, that the universality of capitalism. Not globalized culture, and economic participation, and human rights, ... has only globalized market. We must react by substituting those materialistic values with cooperative economy.

Global Connections to Global Partnerships: Navigating the Changing Landscape of Internationalism and Cross-Border Higher Education

Science.gov (United States)

Olcott, Don, Jr.

2009-01-01

The purpose of this article is to provide continuing higher education leaders with a comprehensive overview of the major considerations for doing business in the global market. Included is an analysis of the driving forces in global higher education and current trends in cross-border programs and a brief review of activities that may be part of a…

Role of tropomyosin as a cross-reacting allergen in sensitization to cockroach in patients from Martinique (French Caribbean island) with a respiratory allergy to mite and a food allergy to crab and shrimp

NARCIS (Netherlands)

Purohit, A.; Shao, J.; Degreef, J. M.; van Leeuwen, A.; van Ree, R.; Pauli, G.; de Blay, F.

2007-01-01

BACKGROUND: Tropomyosin has been described as cross-reacting allergen between mite, cockroach and shrimp. METHODS: In 13 patients with asthma and/or rhinitis sensitized to mite and/or German cockroach and presenting urticaria, oral allergy syndrome or angio-edema upon eating shrimp and/or crab, we

Sharing and community curation of mass spectrometry data with Global Natural Products Social Molecular Networking

DEFF Research Database (Denmark)

Wang, Mingxun; Carver, Jeremy J.; Pevzner, Pavel

2016-01-01

are well-suited to high-throughput characterization of NP, there is a pressing need for an infrastructure to enable sharing and curation of data. We present Global Natural Products Social Molecular Networking (GNPS; http://gnps.ucsd.edu), an open-access knowledge base for community-wide organization...... and sharing of raw, processed or identified tandem mass (MS/MS) spectrometry data. In GNPS, crowdsourced curation of freely available community-wide reference MS libraries will underpin improved annotations. Data-driven social-networking should facilitate identification of spectra and foster collaborations...

Crossing Borders: A Qualitative Study of How Occupational Therapy Educators and Scholars Develop and Sustain Global Partnerships.

Science.gov (United States)

Witchger Hansen, Anne Marie

2015-09-01

The World Federation of Occupational Therapists (WFOT) and the American Occupational Therapy Association promote a globally connected profession that responds to the needs of our diverse societies. Global partnerships are grounded on the principle that cross-cultural experiences are enriching and provide mutual benefits. The purpose of this study was to uncover how occupational therapy educators and scholars perceive and experience (1) developing and sustaining global partnerships and (2) lessons learned. In this qualitative study, 30 occupational therapy educators and researchers completed an online survey. Eight participated in an interview. Results found major themes that help develop and sustain partnerships: building relationship of trust and respect, communicating effectively, cultivating cultural competence, sharing power and resources with collaborators and creating a context for reciprocal learning. Lessons learned include a call to walking humbly, building relationships of trust and respect, establishing open and honest communication, supporting local solutions to local problems, ensuring equality of resources and learning from their global partners. The findings suggest that global partnerships have the potential to transform both partners if the partners engage with mutual understanding and respect. Limitations of this study include a small sample size and participant's pool limited to occupational therapists from United States. Recommendations for future research include qualitative studies to identify model occupational therapy programmes that sustain global partnerships using a diverse sample of international occupational therapy educators and researchers. © 2015 John Wiley & Sons, Ltd.

Studies on antigenic cross-reactivity of Trichuris ovis with host mucosal antigens in goat

Directory of Open Access Journals (Sweden)

Gautam Patra

2015-12-01

Full Text Available Objective: To ascertain whether immunodominant antigens of Trichuris ovis might share and cross react with host molecule. Methods: Two crude protein preparations from anterior and posterior parts of Trichuris ovis were characterized along with host mucosal antigen by double immunodiffusion, sodium dodecyl sulfate-polyacrylamide gel electrophoresis and western blotting technique. Conventional scanning electron microscopy was performed as per standard procedure. Results: Sharp and distinct bands of three antigens have been found in double immunodiffusion using hyperimmune serum raised in rabbit indicating the presence of specific antibody against each antigen. All three antigens have shown major and minor bands with molecular weight ranging from 15 to 110 kDa during sodium dodecyl sulfate-polyacrylamide gel electrophoresis. Conclusions: The antigenic cross-reactivity was thought to result from shared antigens. The existence of paracloacal papillae found in the anterior part of the male was not a unique feature for species differentiation.

Network computing infrastructure to share tools and data in global nuclear energy partnership

International Nuclear Information System (INIS)

Kim, Guehee; Suzuki, Yoshio; Teshima, Naoya

2010-01-01

CCSE/JAEA (Center for Computational Science and e-Systems/Japan Atomic Energy Agency) integrated a prototype system of a network computing infrastructure for sharing tools and data to support the U.S. and Japan collaboration in GNEP (Global Nuclear Energy Partnership). We focused on three technical issues to apply our information process infrastructure, which are accessibility, security, and usability. In designing the prototype system, we integrated and improved both network and Web technologies. For the accessibility issue, we adopted SSL-VPN (Security Socket Layer - Virtual Private Network) technology for the access beyond firewalls. For the security issue, we developed an authentication gateway based on the PKI (Public Key Infrastructure) authentication mechanism to strengthen the security. Also, we set fine access control policy to shared tools and data and used shared key based encryption method to protect tools and data against leakage to third parties. For the usability issue, we chose Web browsers as user interface and developed Web application to provide functions to support sharing tools and data. By using WebDAV (Web-based Distributed Authoring and Versioning) function, users can manipulate shared tools and data through the Windows-like folder environment. We implemented the prototype system in Grid infrastructure for atomic energy research: AEGIS (Atomic Energy Grid Infrastructure) developed by CCSE/JAEA. The prototype system was applied for the trial use in the first period of GNEP. (author)

A commercial ELISA detects high levels of human H5 antibody but cross-reacts with influenza A antibodies.

Science.gov (United States)

Stelzer-Braid, Sacha; Wong, Bruce; Robertson, Peter; Lynch, Garry W; Laurie, Karen; Shaw, Robert; Barr, Ian; Selleck, Paul W; Baleriola, Cristina; Escott, Ros; Katsoulotos, Gregory; Rawlinson, William D

2008-10-01

Commercial serological assays to determine influenza A H5N1 infection are available, although the accuracy and reproducibility of these are not reported in detail. This study aimed to assess the validity of a commercial ELISA H5 hemagglutinin (HA) antibody kit. A commercial ELISA for detection of antibodies towards influenza A H5 HA was evaluated using human sera from vaccinated individuals. The ELISA was used to screen 304 sera with elevated influenza A complement fixation titres collected between the period 1995-2007. The ELISA was found to be accurate for sera with high levels of anti-H5 antibodies, and would be useful in clinical settings where a rapid result is required. Thirteen of the stored sera were positive using the ELISA, but were confirmed as negative for H5N1 exposure using further serological tests. Absorption studies suggested that antibodies towards seasonal H3N2 and H1N1 influenza may cross-react with H5 antigen, giving false positive results with the ELISA.

Potential protective immunogenicity of tetanus toxoid, diphtheria toxoid and Cross Reacting Material 197 (CRM197) when used as carrier proteins in glycoconjugates.

Science.gov (United States)

Bröker, Michael

2016-03-03

When tetanus toxoid (TT), diphtheria toxoid (DT) or Cross Reacting Material 197 (CRM197), a non-toxic diphtheria toxin mutant protein, are used as carrier proteins in glycoconjugate vaccines, these carriers induce a protein specific antibody response as measured by in vitro assays. Here, it was evaluated whether or not glycoconjugates based on TT, DT or CRM197 can induce a protective immune response as measured by potency tests according to the European Pharmacopoeia. It could be shown, that the conjugate carriers TT and DT can induce a protective immune response against a lethal challenge by toxins in animals, while glycoconjugates based on CRM197 failed to induce a protective immune response. Opportunities for new applications of glycoconjugates are discussed.

Heat and mass transfer for turbulent flow of chemically reacting gas in eccentric annular channels

International Nuclear Information System (INIS)

Besedina, T.V.; Tverkovkin, B.E.; Udot, A.V.; Yakushev, A.P.

1988-01-01

Because of the possibility of using dissociating gases as coolants and working bodies of nuclear power plants, it is necessary to develop computational algorithms for calculating heat and mass transfer processes under conditions of nonequilibrium flow of chemically reacting gases not only in axisymmetric channels, but also in channels with a complex transverse cross section (including also in eccentric annular channels). An algorithm is proposed for calculating the velocity, temperature, and concentration fields under conditions of cooling of a cylindrical heat-releasing rod, placed off-center in a circular casing pipe, by a longitudinal flow of chemically reacting gas [N 2 O 4

Linking regional stakeholder scenarios and shared socioeconomic pathways: Quantified West African food and climate futures in a global context

NARCIS (Netherlands)

Palazzo, Amanda; Vervoort, Joost M.; Mason-D’Croz, Daniel; Rutting, Lucas; Havlík, Petr; Islam, Shahnila; Bayala, Jules; Valin, Hugo; Kadi Kadi, Hamé Abdou; Thornton, Philip; Zougmore, Robert

2017-01-01

The climate change research community’s shared socioeconomic pathways (SSPs) are a set of alternative global development scenarios focused on mitigation of and adaptation to climate change. To use these scenarios as a global context that is relevant for policy guidance at regional and national

Governance of global health research consortia: Sharing sovereignty and resources within Future Health Systems.

Science.gov (United States)

Pratt, Bridget; Hyder, Adnan A

2017-02-01

Global health research partnerships are increasingly taking the form of consortia that conduct programs of research in low and middle-income countries (LMICs). An ethical framework has been developed that describes how the governance of consortia comprised of institutions from high-income countries and LMICs should be structured to promote health equity. It encompasses initial guidance for sharing sovereignty in consortia decision-making and sharing consortia resources. This paper describes a first effort to examine whether and how consortia can uphold that guidance. Case study research was undertaken with the Future Health Systems consortium, performs research to improve health service delivery for the poor in Bangladesh, China, India, and Uganda. Data were thematically analysed and revealed that proposed ethical requirements for sharing sovereignty and sharing resources are largely upheld by Future Health Systems. Facilitating factors included having a decentralised governance model, LMIC partners with good research capacity, and firm budgets. Higher labour costs in the US and UK and the funder's policy of allocating funds to consortia on a reimbursement basis prevented full alignment with guidance on sharing resources. The lessons described in this paper can assist other consortia to more systematically link their governance policy and practice to the promotion of health equity. Copyright © 2016 Elsevier Ltd. All rights reserved.

Prediction of reacting atoms for the major biotransformation reactions of organic xenobiotics.

Science.gov (United States)

Rudik, Anastasia V; Dmitriev, Alexander V; Lagunin, Alexey A; Filimonov, Dmitry A; Poroikov, Vladimir V

2016-01-01

The knowledge of drug metabolite structures is essential at the early stage of drug discovery to understand the potential liabilities and risks connected with biotransformation. The determination of the site of a molecule at which a particular metabolic reaction occurs could be used as a starting point for metabolite identification. The prediction of the site of metabolism does not always correspond to the particular atom that is modified by the enzyme but rather is often associated with a group of atoms. To overcome this problem, we propose to operate with the term "reacting atom", corresponding to a single atom in the substrate that is modified during the biotransformation reaction. The prediction of the reacting atom(s) in a molecule for the major classes of biotransformation reactions is necessary to generate drug metabolites. Substrates of the major human cytochromes P450 and UDP-glucuronosyltransferases from the Biovia Metabolite database were divided into nine groups according to their reaction classes, which are aliphatic and aromatic hydroxylation, N- and O-glucuronidation, N-, S- and C-oxidation, and N- and O-dealkylation. Each training set consists of positive and negative examples of structures with one labelled atom. In the positive examples, the labelled atom is the reacting atom of a particular reaction that changed adjacency. Negative examples represent non-reacting atoms of a particular reaction. We used Labelled Multilevel Neighbourhoods of Atoms descriptors for the designation of reacting atoms. A Bayesian-like algorithm was applied to estimate the structure-activity relationships. The average invariant accuracy of prediction obtained in leave-one-out and 20-fold cross-validation procedures for five human isoforms of cytochrome P450 and all isoforms of UDP-glucuronosyltransferase varies from 0.86 to 0.99 (0.96 on average). We report that reacting atoms may be predicted with reasonable accuracy for the major classes of metabolic reactions

GLOBALIZATION & REGIONALIZATION IN INTERNATIONAL TRADE

Directory of Open Access Journals (Sweden)

Ramona Frunză

2009-12-01

Full Text Available The concept of globalization refers to the growing interdependence of countries, resulting from the increasing integration of trade, finance, investments, labor markets and ideas in one globalmarketplace. The most important elements of this process are the international trade and the cross-border investment flows. Economic globalization has increased the specialization of workers, while the companies compete in global markets. Even globalization has recently become a common topic in academic discourse, many economists focused, from the 1980s and 1990s, in addition to globalization, on regionalization - the growth of networks of interdependence within multinational regions of the world. The recent decades arecharacterized by the fact that the world trade grew faster than world output, which implies that an increasing share of world GDP crosses international borders. The trend is explained, mostly, by thesubstantially declining of the trade barriers during the same period, as a result of successive trade negotiation rounds under the auspices of the GATT/WTO, unilateral trade liberalization and regional tradeagreements. Even there are global connections between all the countries, the strongest political and economic integration is being created within a few specific regions of the world: Europe, North America and East Asia.

Mathematical aspects of reacting and diffusing systems

CERN Document Server

Fife, Paul C

1979-01-01

Modeling and analyzing the dynamics of chemical mixtures by means of differ- tial equations is one of the prime concerns of chemical engineering theorists. These equations often take the form of systems of nonlinear parabolic partial d- ferential equations, or reaction-diffusion equations, when there is diffusion of chemical substances involved. A good overview of this endeavor can be had by re- ing the two volumes by R. Aris (1975), who himself was one of the main contributors to the theory. Enthusiasm for the models developed has been shared by parts of the mathematical community, and these models have, in fact, provided motivation for some beautiful mathematical results. There are analogies between chemical reactors and certain biological systems. One such analogy is rather obvious: a single living organism is a dynamic structure built of molecules and ions, many of which react and diffuse. Other analogies are less obvious; for example, the electric potential of a membrane can diffuse like a chemical, and ...

[A case of shared psychotic disorder (folie à deux) with original aspects associated with cross-cultural elements].

Science.gov (United States)

Cuoco, Valentina; Colletti, Chiara; Anastasia, Annalisa; Weisz, Filippo; Bersani, Giuseppe

2015-01-01

Shared psychotic disorder (folie à deux) is a rare condition characterized by the transmission of delusional aspects from a patient (the "dominant partner") to another (the "submissive partner") linked to the first by a close relationship. We report the case of two Moroccan sisters who have experienced a combined delusional episode diagnosed as shared psychotic disorder. In these circumstances, assessment of symptoms from a cross-cultural perspective is a key factor for proper diagnostic evaluation.

Cross-Cultural School-Based Encounters as Global Health Education

Science.gov (United States)

Bruselius-Jensen, Maria; Renwick, Kerry; Aagaard-Hansen, Jens

2017-01-01

Objective: Drawing on the concepts of the cosmopolitan person and democratic health education, this article explores the merits of primary school-based, cross-cultural dialogues for global health education. Design: A qualitative study of the learning outcomes of the Move/Eat/Learn (MEL) project. MEL facilitates cultural meetings, primarily…

Ethics policies and ethics work in cross-national genetic research and data sharing

DEFF Research Database (Denmark)

Hoeyer, Klaus; Tupasela, Aaro; Rasmussen, Malene B.

2017-01-01

of scientific work. This paper takes its point of departure in the practices of a Danish laboratory with great experience in international collaboration regarding genetic research. We focus on a simple query, what makes genetic material and health data flow, and which hopes and concerns travel along with them......In recent years, cross-national collaboration in medical research has gained increased policy attention. Policies are developed to enhance data sharing, ensure open-access, and harmonize international standards and ethics rules in order to promote access to existing resources and increase...... scientific output. In tandem with this promotion of data sharing, numerous ethics policies are developed to control data flows and protect privacy and confidentiality. Both sets of policy making, however, pay limited attention to the moral decisions and social ties enacted in the everyday routines...

Sharing City

DEFF Research Database (Denmark)

This magazine offers an insight into the growing commercial innovation, civic movements, and political narratives surrounding sharing economy services, solutions and organisational types. It presents a cross-section of the manifold sharing economy services and solutions that can be found in Denmark....... Moreover, 15 thought leading experts - professionals and academic - have been invited to give their perspective on sharing economy for cities. This magazine touches upon aspects of the sharing economy as mobility, communities, sustainability, business development, mobility, and urban-rural relation....

Pre-existing IgG antibodies cross-reacting with the Fab region of infliximab predict efficacy and safety of infliximab therapy in inflammatory bowel disease

DEFF Research Database (Denmark)

Steenholdt, Casper; Palarasah, Yaseelan; Bendtzen, Klaus

2013-01-01

are common and may cross-react with the murine part of IFX. AIM: To investigate if Abs binding to IFX's Fab region (IFX-Fab) are present in IBD patients before exposure to IFX, and whether they predict efficacy and safety of IFX therapy. METHODS: Observational, retrospective cohort study of patients with CD...... (n = 29) and UC (n = 22). RESULTS: Pre-treatment levels of IFX-Fab reactive IgG Abs were significantly lower in CD patients in remission after 1 year of maintenance IFX (median 91 mU/L, n = 8) than in the rest of the patients (639 mU/L, n = 21; P ...

Stochastic models for turbulent reacting flows

Energy Technology Data Exchange (ETDEWEB)

Kerstein, A. [Sandia National Laboratories, Livermore, CA (United States)

1993-12-01

The goal of this program is to develop and apply stochastic models of various processes occurring within turbulent reacting flows in order to identify the fundamental mechanisms governing these flows, to support experimental studies of these flows, and to further the development of comprehensive turbulent reacting flow models.

Cross-reacting carbohydrate determinants and hymenoptera venom allergy.

Science.gov (United States)

Brehler, Randolf; Grundmann, Sonja; Stöcker, Benedikt

2013-08-01

Insect venom allergy is an important cause of anaphylaxis. Venom immunotherapy assume the clear identification of the culprit insect, but this is impeded by Immunoglobulin E (IgE) antibodies to cross reactive carbohydrate determinant (CCD) epitopes of common glycoproteins. Here we give an overview about inducers, importance, and relevance of anti-N-Glycan CCD IgE antibodies. Pollen exposure and insect stings induce anti-CCD IgE antibodies interfering with in-vitro tests for allergy diagnosis due to extensive IgE cross-reactivity. Instead of being biologically active these antibodies are irrelevant for allergic reactions due to hymenoptera stings. The general response of the immune system to the ubiquitous exposure to N-glycan containing glycoproteins is still a matter of debate. CCD specific IgG antibodies in sera of bee keepers suggest tolerance induction due to high-dose exposure. Tolerance induction by pollen and food glycoproteins has not been proved. Hymenoptera stings and pollen exposure induce anti-CCD IgE. In regard to anaphylaxis due to Hymenoptera stings these antibodies are not clinically relevant, but they are important for the specificity of in-vitro tests proving insect venom allergy. The introduction of component based diagnostic IgE testing improves the specificity of in-vitro tests if proteins devoid of CCD epitopes are used.

Shared Sanitation Versus Individual Household Latrines in Urban Slums: A Cross-Sectional Study in Orissa, India.

Science.gov (United States)

Heijnen, Marieke; Routray, Parimita; Torondel, Belen; Clasen, Thomas

2015-08-01

A large and growing proportion of the global population rely on shared sanitation facilities despite evidence of a potential increased risk of adverse health outcomes compared with individual household latrines (IHLs). We sought to explore differences between households relying on shared sanitation versus IHLs in terms of demographics, sanitation facilities, and fecal exposure. We surveyed 570 households from 30 slums in Orissa, India, to obtain data on demographics, water, sanitation, and hygiene. Latrine spot-checks were conducted to collect data on indicators of use, privacy, and cleanliness. We collected samples of drinking water and hand rinses to assess fecal contamination. Households relying on shared sanitation were poorer and less educated than those accessing IHLs. Individuals in sharing households were more likely to practice open defecation. Shared facilities were less likely to be functional, less clean, and more likely to have feces and flies. No differences in fecal contamination of drinking water or hand-rinse samples were found. Important differences exist among households accessing shared facilities versus IHLs that may partly explain the apparent adverse health outcomes associated with shared sanitation. As these factors may capture differences in risk and promote sanitary improvements, they should be considered in future policy. © The American Society of Tropical Medicine and Hygiene.

The PREVIEW Global Risk Data Platform: a geoportal to serve and share global data on risk to natural hazards

Directory of Open Access Journals (Sweden)

G. Giuliani

2011-01-01

Full Text Available With growing world population and concentration in urban and coastal areas, the exposure to natural hazards is increasing and results in higher risk of human and economic losses. Improving the identification of areas, population and assets potentially exposed to natural hazards is essential to reduce the consequences of such events. Disaster risk is a function of hazard, exposure and vulnerability. Modelling risk at the global level requires accessing and processing a large number of data, from numerous collaborating centres.

These data need to be easily updated, and there is a need for centralizing access to this information as well as simplifying its use for non GIS specialists. The Hyogo Framework for Action provides the mandate for data sharing, so that governments and international development agencies can take appropriate decision for disaster risk reduction.

Timely access and easy integration of geospatial data are essential to support efforts in Disaster Risk Reduction. However various issues in data availability, accessibility and integration limit the use of such data. In consequence, a framework that facilitate sharing and exchange of geospatial data on natural hazards should improve decision-making process. The PREVIEW Global Risk Data Platform is a highly interactive web-based GIS portal supported by a Spatial Data Infrastructure that offers free and interoperable access to more than 60 global data sets on nine types of natural hazards (tropical cyclones and related storm surges, drought, earthquakes, biomass fires, floods, landslides, tsunamis and volcanic eruptions and related exposure and risk. This application portrays an easy-to-use online interactive mapping interface so that users can easily work with it and seamlessly integrate data in their own data flow using fully compliant OGC Web Services (OWS.

The PREVIEW Global Risk Data Platform: a geoportal to serve and share global data on risk to natural hazards

Science.gov (United States)

Giuliani, G.; Peduzzi, P.

2011-01-01

With growing world population and concentration in urban and coastal areas, the exposure to natural hazards is increasing and results in higher risk of human and economic losses. Improving the identification of areas, population and assets potentially exposed to natural hazards is essential to reduce the consequences of such events. Disaster risk is a function of hazard, exposure and vulnerability. Modelling risk at the global level requires accessing and processing a large number of data, from numerous collaborating centres. These data need to be easily updated, and there is a need for centralizing access to this information as well as simplifying its use for non GIS specialists. The Hyogo Framework for Action provides the mandate for data sharing, so that governments and international development agencies can take appropriate decision for disaster risk reduction. Timely access and easy integration of geospatial data are essential to support efforts in Disaster Risk Reduction. However various issues in data availability, accessibility and integration limit the use of such data. In consequence, a framework that facilitate sharing and exchange of geospatial data on natural hazards should improve decision-making process. The PREVIEW Global Risk Data Platform is a highly interactive web-based GIS portal supported by a Spatial Data Infrastructure that offers free and interoperable access to more than 60 global data sets on nine types of natural hazards (tropical cyclones and related storm surges, drought, earthquakes, biomass fires, floods, landslides, tsunamis and volcanic eruptions) and related exposure and risk. This application portrays an easy-to-use online interactive mapping interface so that users can easily work with it and seamlessly integrate data in their own data flow using fully compliant OGC Web Services (OWS).

Accounting for sampling patterns reverses the relative importance of trade and climate for the global sharing of exotic plants

Science.gov (United States)

Sofaer, Helen R.; Jarnevich, Catherine S.

2017-01-01

AimThe distributions of exotic species reflect patterns of human-mediated dispersal, species climatic tolerances and a suite of other biotic and abiotic factors. The relative importance of each of these factors will shape how the spread of exotic species is affected by ongoing economic globalization and climate change. However, patterns of trade may be correlated with variation in scientific sampling effort globally, potentially confounding studies that do not account for sampling patterns.LocationGlobal.Time periodMuseum records, generally from the 1800s up to 2015.Major taxa studiedPlant species exotic to the United States.MethodsWe used data from the Global Biodiversity Information Facility (GBIF) to summarize the number of plant species with exotic occurrences in the United States that also occur in each other country world-wide. We assessed the relative importance of trade and climatic similarity for explaining variation in the number of shared species while evaluating several methods to account for variation in sampling effort among countries.ResultsAccounting for variation in sampling effort reversed the relative importance of trade and climate for explaining numbers of shared species. Trade was strongly correlated with numbers of shared U.S. exotic plants between the United States and other countries before, but not after, accounting for sampling variation among countries. Conversely, accounting for sampling effort strengthened the relationship between climatic similarity and species sharing. Using the number of records as a measure of sampling effort provided a straightforward approach for the analysis of occurrence data, whereas species richness estimators and rarefaction were less effective at removing sampling bias.Main conclusionsOur work provides support for broad-scale climatic limitation on the distributions of exotic species, illustrates the need to account for variation in sampling effort in large biodiversity databases, and highlights the

Epidemic 2014 enterovirus D68 cross-reacts with human rhinovirus on a respiratory molecular diagnostic platform.

Science.gov (United States)

McAllister, Shane C; Schleiss, Mark R; Arbefeville, Sophie; Steiner, Marie E; Hanson, Ryan S; Pollock, Catherine; Ferrieri, Patricia

2015-01-01

Enterovirus D68 (EV-D68) is an emerging virus known to cause sporadic disease and occasional epidemics of severe lower respiratory tract infection. However, the true prevalence of infection with EV-D68 is unknown, due in part to the lack of a rapid and specific nucleic acid amplification test as well as the infrequency with which respiratory samples are analyzed by enterovirus surveillance programs. During the 2014 EV-D68 epidemic in the United States, we noted an increased frequency of "low-positive" results for human rhinovirus (HRV) detected in respiratory tract samples using the GenMark Diagnostics eSensor respiratory viral panel, a multiplex PCR assay able to detect 14 known respiratory viruses but not enteroviruses. We simultaneously noted markedly increased admissions to our Pediatric Intensive Care Unit for severe lower respiratory tract infections in patients both with and without a history of reactive airway disease. Accordingly, we hypothesized that these "low-positive" RVP results were due to EV-D68 rather than rhinovirus infection. Sequencing of the picornavirus 5' untranslated region (5'-UTR) of 49 samples positive for HRV by the GenMark RVP revealed that 33 (67.3%) were in fact EV-D68. Notably, the mean intensity of the HRV RVP result was significantly lower in the sequence-identified EV-D68 samples (20.3 nA) compared to HRV (129.7 nA). Using a cut-off of 40 nA for the differentiation of EV-D68 from HRV resulted in 94% sensitivity and 88% specificity. The robust diagnostic characteristics of our data suggest that the cross-reactivity of EV-D68 and HRV on the GenMark Diagnostics eSensor RVP platform may be an important factor to consider in making accurate molecular diagnosis of EV-D68 at institutions utilizing this system or other molecular respiratory platforms that may also cross-react.

Integrating genome-based informatics to modernize global disease monitoring, information sharing, and response

DEFF Research Database (Denmark)

Aarestrup, Frank Møller; Brown, Eric W; Detter, Chris

2012-01-01

The rapid advancement of genome technologies holds great promise for improving the quality and speed of clinical and public health laboratory investigations and for decreasing their cost. The latest generation of genome DNA sequencers can provide highly detailed and robust information on disease...... typing methods to provide point-of-care clinical diagnosis and other essential information for quicker and better treatment of patients. Provided there is free-sharing of information by all clinical and public health laboratories, these genomic tools could spawn a global system of linked databases......-causing microbes, and in the near future these technologies will be suitable for routine use in national, regional, and global public health laboratories. With additional improvements in instrumentation, these next- or third-generation sequencers are likely to replace conventional culture-based and molecular...

Frequencies of Private Mentions and Sharing of Mammography and Breast Cancer Terms on Facebook: A Pilot Study

Science.gov (United States)

Chetlen, Alison; Segel, Joel; Schetter, Susann

2017-01-01

Background The most popular social networking site in the United States is Facebook, an online forum where circles of friends create, share, and interact with each other’s content in a nonpublic way. Objective Our objectives were to understand (1) the most commonly used terms and phrases relating to breast cancer screening, (2) the most commonly shared website links that other women interacted with, and (3) the most commonly shared website links, by age groups. Methods We used a novel proprietary tool from Facebook to analyze all of the more than 1.7 million unique interactions (comments on stories, reshares, and emoji reactions) and stories associated with breast cancer screening keywords that were generated by more than 1.1 million unique female Facebook users over the 1 month between November 15 and December 15, 2016. We report frequency distributions of the most popular shared Web content by age group and keywords. Results On average, each of 59,000 unique stories during the month was reshared 1.5 times, commented on nearly 8 times, and reacted to more than 20 times by other users. Posted stories were most often authored by women aged 45-54 years. Users shared, reshared, commented on, and reacted to website links predominantly to e-commerce sites (12,200/1.7 million, 36% of all the most popular links), celebrity news (n=8800, 26%), and major advocacy organizations (n=4900, 15%; almost all accounted for by the American Cancer Society breast cancer site). Conclusions On Facebook, women shared and reacted to links to commercial and informative websites regarding breast cancer and screening. This information could inform patient outreach regarding breast cancer screening, indirectly through better understanding of key issues, and directly through understanding avenues for paid messaging to women authoring and reacting to content in this space. PMID:28600279

Production sharing agreements

International Nuclear Information System (INIS)

1994-01-01

This paper, which was presented at the Production Sharing Agreement seminar, discusses economic rent, negotiations, trends in fiscal system development, and concessionary systems. Production sharing contracts, risk service contracts, joint ventures and the global market are examined. (UK)

House dust mite (Der p 10) and crustacean allergic patients may react to food containing Yellow mealworm proteins.

Science.gov (United States)

Verhoeckx, Kitty C M; van Broekhoven, Sarah; den Hartog-Jager, Constance F; Gaspari, Marco; de Jong, Govardus A H; Wichers, Harry J; van Hoffen, Els; Houben, Geert F; Knulst, André C

2014-03-01

Due to the imminent growth of the world population, shortage of protein sources for human consumption will arise in the near future. Alternative and sustainable protein sources (e.g. insects) are being explored for the production of food and feed. In this project, the safety of Yellow mealworms (Tenebrio molitor L.) for human consumption was tested using approaches as advised by the European Food Safety Authority for allergenicity risk assessment. Different Yellow mealworm protein fractions were prepared, characterised, and tested for cross-reactivity using sera from patients with an inhalation or food allergy to biologically related species (House dust mite (HDM) and crustaceans) by immunoblotting and basophil activation. Furthermore, the stability was investigated using an in vitro pepsin digestion test. IgE from HDM- and crustacean allergic patients cross-reacted with Yellow mealworm proteins. This cross-reactivity was functional, as shown by the induction of basophil activation. The major cross-reactive proteins were identified as tropomyosin and arginine kinase, which are well known allergens in arthropods. These proteins were moderately stable in the pepsin stability test. Based on these cross-reactivity studies, there is a realistic possibility that HDM- and crustacean allergic patients may react to food containing Yellow mealworm proteins. Copyright © 2014 Elsevier Ltd. All rights reserved.

Computer-Mediated Education And Globalization - A Case Study On Cross-border Course "Globalization and Media"

Directory of Open Access Journals (Sweden)

Luyan Li

2004-04-01

Full Text Available This paper studies computer mediated education in social science, in particular, communication studies. As universities in the United States build closer relationships with foreign universities, cross-border education becomes more feasible with the assistance of web technology. To illustrate how this can be done, a trial course Globalization and Media is offered to students in both China and US from a US university. In the first part of the online tutorial, it is mainly instructor-based as the theories in media effects and globalization are introduced to the students. In the second part, the course becomes more application-based as students are requested to accomplish two tasks: firstly, study one of their own countries' major media institutions and share their findings in the online discussion board of the course website. After intense discussions of the different structures and functions of media institutions from the two countries, students are asked to conduct content analysis of a newspaper of their own countries over one common issue, e.g., the coverage of Iraq war. Their findings are again posted on the course discussion broad. Through these exercises students are able to see both sides and have a deeper understanding of the differences of media systems from a global angle. With computer mediated teaching, people from different countries can effectively learn from and exchange viewpoints with each other, without physically moving from one place to another. However, because only those who are computer literate and proficient in English could benefit from it, this may further deepen the gap of digital divide and exacerbate the dilution of cultures in the developing countries. Another concern is that because the instructor and the students are not in the same room, and may not even access to the course materials at the same time, although this provides convenience for the students to set their own time and pace, it also requires tremendous

Cross-covariance based global dynamic sensitivity analysis

Science.gov (United States)

Shi, Yan; Lu, Zhenzhou; Li, Zhao; Wu, Mengmeng

2018-02-01

For identifying the cross-covariance source of dynamic output at each time instant for structural system involving both input random variables and stochastic processes, a global dynamic sensitivity (GDS) technique is proposed. The GDS considers the effect of time history inputs on the dynamic output. In the GDS, the cross-covariance decomposition is firstly developed to measure the contribution of the inputs to the output at different time instant, and an integration of the cross-covariance change over the specific time interval is employed to measure the whole contribution of the input to the cross-covariance of output. Then, the GDS main effect indices and the GDS total effect indices can be easily defined after the integration, and they are effective in identifying the important inputs and the non-influential inputs on the cross-covariance of output at each time instant, respectively. The established GDS analysis model has the same form with the classical ANOVA when it degenerates to the static case. After degeneration, the first order partial effect can reflect the individual effects of inputs to the output variance, and the second order partial effect can reflect the interaction effects to the output variance, which illustrates the consistency of the proposed GDS indices and the classical variance-based sensitivity indices. The MCS procedure and the Kriging surrogate method are developed to solve the proposed GDS indices. Several examples are introduced to illustrate the significance of the proposed GDS analysis technique and the effectiveness of the proposed solution.

Mechanism for Self-Reacted Friction Stir Welding

Science.gov (United States)

Venable, Richard; Bucher, Joseph

2004-01-01

A mechanism has been designed to apply the loads (the stirring and the resection forces and torques) in self-reacted friction stir welding. This mechanism differs somewhat from mechanisms used in conventional friction stir welding, as described below. The tooling needed to apply the large reaction loads in conventional friction stir welding can be complex. Self-reacted friction stir welding has become popular in the solid-state welding community as a means of reducing the complexity of tooling and to reduce costs. The main problems inherent in self-reacted friction stir welding originate in the high stresses encountered by the pin-and-shoulder assembly that produces the weld. The design of the present mechanism solves the problems. The mechanism includes a redesigned pin-and-shoulder assembly. The welding torque is transmitted into the welding pin by a square pin that fits into a square bushing with set-screws. The opposite or back shoulder is held in place by a Woodruff key and high-strength nut on a threaded shaft. The Woodruff key reacts the torque, while the nut reacts the tensile load on the shaft.

Calorimetry of non-reacting systems

CERN Document Server

McCullough, John P

2013-01-01

Experimental Thermodynamics, Volume 1: Calorimetry of Non-Reacting Systems covers the heat capacity determinations for chemical substances in the solid, liquid, solution, and vapor states, at temperatures ranging from near the absolute zero to the highest at which calorimetry is feasible.This book is divided into 14 chapters. The first four chapters provide background information and general principles applicable to all types of calorimetry of non-reacting systems. The remaining 10 chapters deal with specific types of calorimetry. Most of the types of calorimetry treated are developed over a c

Global identification, xenophobia and globalisation: A cross-national exploration.

Science.gov (United States)

Ariely, Gal

2017-12-01

This paper explores the ways in which globalisation influences social identity. Combining a psychological social-identity framework with sociological considerations regarding the contextual impact of globalisation, it tests whether global identification-that is, people's identification as global citizens-constitutes an inclusive category, negatively linked to xenophobic attitudes towards immigrants across countries and whether the actual country level of globalisation moderates the relationship between global identification and xenophobia. Unlike most psychological studies of globalisation, it draws its data from 124 national samples across 86 countries, with 154,760 respondents overall, using three different cross-national surveys. Study 1 (International Social Survey Program National Identity Module III 2013; N = 39,426, countries = 32) evinces that while global identification is in fact negatively linked to xenophobia, the correlation is moderated by the country level of globalisation, countries marked by higher levels of globalisation exhibiting a stronger negative relation between global identification and xenophobia than those characterised by a lower level of globalisation. Study 2 (European Values Study 2008; N = 53,083, countries = 44) and Study 3 (World Values Survey 6; N = 65,251, countries = 48) replicated these results across other countries employing dissimilar scales for global identification and xenophobia. © 2016 International Union of Psychological Science.

Effects of continuum breakdown on hypersonic aerothermodynamics for reacting flow

Science.gov (United States)

Holman, Timothy D.; Boyd, Iain D.

2011-02-01

This study investigates the effects of continuum breakdown on the surface aerothermodynamic properties (pressure, stress, and heat transfer rate) of a sphere in a Mach 25 flow of reacting air in regimes varying from continuum to a rarefied gas. Results are generated using both continuum [computational fluid dynamics (CFD)] and particle [direct simulation Monte Carlo (DSMC)] approaches. The DSMC method utilizes a chemistry model that calculates the backward rates from an equilibrium constant. A preferential dissociation model is modified in the CFD method to better compare with the vibrationally favored dissociation model that is utilized in the DSMC method. Tests of these models are performed to confirm their validity and to compare the chemistry models in both numerical methods. This study examines the effect of reacting air flow on continuum breakdown and the surface properties of the sphere. As the global Knudsen number increases, the amount of continuum breakdown in the flow and on the surface increases. This increase in continuum breakdown significantly affects the surface properties, causing an increase in the differences between CFD and DSMC. Explanations are provided for the trends observed.

THE PERFORMANCE OF GLOBAL BANKS IN THEIR CROSS-BORDER ACTIVITY

Directory of Open Access Journals (Sweden)

Andreea POPOVICI

2015-04-01

Full Text Available The crisis that affected the global financial stability and the economy in 2007-09 has reinforced the need to rethink some of the approaches adopted by the financial community in assessing banks’ performance. The aim of this paper is to see if global banks improve their performance due to their cross-border activity, whether we speak about mergers or acquisitions of local banks or we speak about other ways a global bank begins the activity in a different country. As methodology, we will analyze the dynamic of ROAA and ROAE during 2006-2013 in the case of two global banks, Société Générale and Erste Group, and their branches in countries from Central and Eastern Europe. At the end of the paper, we will compare the results for each big bank and their branches.

Using beryllium-7 to assess cross-tropopause transport in global models

Energy Technology Data Exchange (ETDEWEB)

Liu, Hongyu [National Institute of Aerospace, Hampton, VA (United States); Considine, David B. [NASA Langley Research Center, Hampton, VA (United States); Horowitz, Larry W. [NOAA Geophysical Fluid and Dynamics Laboratory, Princeton, NJ (United States); and others

2016-07-01

We use the Global Modeling Initiative (GMI) modeling framework to assess the utility of cosmogenic beryllium-7 ({sup 7}Be), a natural aerosol tracer, for evaluating cross-tropopause transport in global models. The GMI chemical transport model (CTM) was used to simulate atmospheric {sup 7}Be distributions using four different meteorological data sets (GEOS1-STRAT DAS, GISS II{sup '} GCM, fvGCM, and GEOS4-DAS), featuring significantly different stratosphere-troposphere exchange (STE) characteristics. The simulations were compared with the upper troposphere and/or lower stratosphere (UT/LS) {sup 7}Be climatology constructed from ∝ 25 years of aircraft and balloon data, as well as climatological records of surface concentrations and deposition fluxes. Comparison of the fraction of surface air of stratospheric origin estimated from the {sup 7}Be simulations with observationally derived estimates indicates excessive cross-tropopause transport at mid-latitudes in simulations using GEOS1-STRAT and at high latitudes using GISS II{sup '} meteorological data. These simulations also overestimate {sup 7}Be deposition fluxes at mid-latitudes (GEOS1-STRAT) and at high latitudes (GISS II{sup '}), respectively. We show that excessive cross-tropopause transport of {sup 7}Be corresponds to overestimated stratospheric contribution to tropospheric ozone. Our perspectives on STE in these meteorological fields based on {sup 7}Be simulations are consistent with previous modeling studies of tropospheric ozone using the same meteorological fields. We conclude that the observational constraints for {sup 7}Be and observed {sup 7}Be total deposition fluxes can be used routinely as a first-order assessment of cross-tropopause transport in global models.

Direct numerical simulation of turbulent reacting flows

Energy Technology Data Exchange (ETDEWEB)

Chen, J.H. [Sandia National Laboratories, Livermore, CA (United States)

1993-12-01

The development of turbulent combustion models that reflect some of the most important characteristics of turbulent reacting flows requires knowledge about the behavior of key quantities in well defined combustion regimes. In turbulent flames, the coupling between the turbulence and the chemistry is so strong in certain regimes that is is very difficult to isolate the role played by one individual phenomenon. Direct numerical simulation (DNS) is an extremely useful tool to study in detail the turbulence-chemistry interactions in certain well defined regimes. Globally, non-premixed flames are controlled by two limiting cases: the fast chemistry limit, where the turbulent fluctuations. In between these two limits, finite-rate chemical effects are important and the turbulence interacts strongly with the chemical processes. This regime is important because industrial burners operate in regimes in which, locally the flame undergoes extinction, or is at least in some nonequilibrium condition. Furthermore, these nonequilibrium conditions strongly influence the production of pollutants. To quantify the finite-rate chemistry effect, direct numerical simulations are performed to study the interaction between an initially laminar non-premixed flame and a three-dimensional field of homogeneous isotropic decaying turbulence. Emphasis is placed on the dynamics of extinction and on transient effects on the fine scale mixing process. Differential molecular diffusion among species is also examined with this approach, both for nonreacting and reacting situations. To address the problem of large-scale mixing and to examine the effects of mean shear, efforts are underway to perform large eddy simulations of round three-dimensional jets.

Towards Modern Collaborative Knowledge Sharing Systems

CERN Document Server

Świrski, Konrad

2012-01-01

The development of new technologies still accelerates. As a result the requirement of easy access to high quality information is essential in modern scientific society. We believe that new cloud-based online system will replace the old system of books and magazines in the future. This is mainly because contemporary system of journal and conference publications appears to be outdated, especially in such domains as computer science, because process of publishing of an article takes too much time. In this book a new approach of sharing knowledge is proposed. The main idea behind this new approach is to take advantage of collaboration techniques used in industry to share the knowledge and build teams which work on the same subject at different locations. This will allow to accelerate the exchange of information between scientists and allow to build global teams of researchers who deal with the same scientific subjects. Furthermore, an easy access to structured knowledge will facilitate cross domain cooperation. T...

A Brief Analysis on Cross-cultural Communication Strategy of Chinese Films under the Context of Globalization

Directory of Open Access Journals (Sweden)

Cao Zhiyong

2016-03-01

Full Text Available With the development of globalization waves, the cross-cultural communication becomes more and more common nowadays. Chinese films, as a kind of mass media and the carrier of ideology, must meet the challenge in the world with active attitudes and take part in cross-cultural communication worldwide extensively. The context of globalization is not only a challenge but also an opportunity for Chinese films and if Chinese films want to be successful in the process of cross-cultural communication, it must find out a conjoint point between globalization and location to implement dual-coding of them. With the objective of consensus but different for the cultural demands of cross-cultural communication, the communicational strategies in culture，subject，art and operation must extensively use for reference and boldly create to renew the situation of Chinese films．

Frequencies of Private Mentions and Sharing of Mammography and Breast Cancer Terms on Facebook: A Pilot Study.

Science.gov (United States)

Huesch, Marco; Chetlen, Alison; Segel, Joel; Schetter, Susann

2017-06-09

The most popular social networking site in the United States is Facebook, an online forum where circles of friends create, share, and interact with each other's content in a nonpublic way. Our objectives were to understand (1) the most commonly used terms and phrases relating to breast cancer screening, (2) the most commonly shared website links that other women interacted with, and (3) the most commonly shared website links, by age groups. We used a novel proprietary tool from Facebook to analyze all of the more than 1.7 million unique interactions (comments on stories, reshares, and emoji reactions) and stories associated with breast cancer screening keywords that were generated by more than 1.1 million unique female Facebook users over the 1 month between November 15 and December 15, 2016. We report frequency distributions of the most popular shared Web content by age group and keywords. On average, each of 59,000 unique stories during the month was reshared 1.5 times, commented on nearly 8 times, and reacted to more than 20 times by other users. Posted stories were most often authored by women aged 45-54 years. Users shared, reshared, commented on, and reacted to website links predominantly to e-commerce sites (12,200/1.7 million, 36% of all the most popular links), celebrity news (n=8800, 26%), and major advocacy organizations (n=4900, 15%; almost all accounted for by the American Cancer Society breast cancer site). On Facebook, women shared and reacted to links to commercial and informative websites regarding breast cancer and screening. This information could inform patient outreach regarding breast cancer screening, indirectly through better understanding of key issues, and directly through understanding avenues for paid messaging to women authoring and reacting to content in this space. ©Marco Huesch, Alison Chetlen, Joel Segel, Susann Schetter. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 09.06.2017.

IHE cross-enterprise document sharing for imaging: interoperability testing software

Directory of Open Access Journals (Sweden)

Renaud Bérubé

2010-09-01

Full Text Available Abstract Background With the deployments of Electronic Health Records (EHR, interoperability testing in healthcare is becoming crucial. EHR enables access to prior diagnostic information in order to assist in health decisions. It is a virtual system that results from the cooperation of several heterogeneous distributed systems. Interoperability between peers is therefore essential. Achieving interoperability requires various types of testing. Implementations need to be tested using software that simulates communication partners, and that provides test data and test plans. Results In this paper we describe a software that is used to test systems that are involved in sharing medical images within the EHR. Our software is used as part of the Integrating the Healthcare Enterprise (IHE testing process to test the Cross Enterprise Document Sharing for imaging (XDS-I integration profile. We describe its architecture and functionalities; we also expose the challenges encountered and discuss the elected design solutions. Conclusions EHR is being deployed in several countries. The EHR infrastructure will be continuously evolving to embrace advances in the information technology domain. Our software is built on a web framework to allow for an easy evolution with web technology. The testing software is publicly available; it can be used by system implementers to test their implementations. It can also be used by site integrators to verify and test the interoperability of systems, or by developers to understand specifications ambiguities, or to resolve implementations difficulties.

Large-Eddy Simulations of Reacting Liquid Spray

Science.gov (United States)

Lederlin, Thomas; Sanjose, Marlene; Gicquel, Laurent; Cuenot, Benedicte; Pitsch, Heinz; Poinsot, Thierry

2008-11-01

Numerical simulation, which is commonly used in many stages of aero-engine design, still has to demonstrate its predictive capability for two-phase reacting flows. This study is a collaboration between Stanford University and CERFACS to perform LES of a realistic spray combustor installed at ONERA, Toulouse. The experimental configuration is computed on the same unstructured mesh with two different solvers: Stanford's CDP code and CERFACS's AVBP code. CDP uses a low-Mach, variable-density solver with implicit time advancement. Droplets are tracked in a Lagrangian point-particle framework. The combustion model uses a flamelet approach, based on two transported scalars, mixture fraction and reaction progress variable. AVBP is a fully compressible solver with explicit time advancement. The liquid phase is described with an Eulerian method. The flame-turbulence interaction is modeled using a dynamically-thickened flame. Results are compared with experimental data for three regimes: purely gaseous non-reacting flow, non-reacting flow with evaporating droplets, reacting flow with droplets. Both simulations show a good agreement with experimental data and also stress the difference and relative advantages of the numerical methods.

Academic Globalization And Ice: Cross-Cultural Research And Transnational Education

Directory of Open Access Journals (Sweden)

Marta Szabo White

2012-10-01

Full Text Available As the Lion said to the Man, "There are many statues of men slaying lions, but if only the lions were sculptors there might be quite a different set of statues." - Aesop Commensurate with Aesop's message of the sculptor matters, so does the communicator, the language and surprisingly, business context. The evolution from the experientially-based Cultureactive to the theoretically-based ICE, from first-generation to second-generation, this paper underscores the marriage of cross-cultural research and transnational education. Both Cultureactive and ICE serve at the pleasure of Globalization, and more importantly, Academic Globalization and Transnational Education. The impetus for this paper derives from two pivotal questions: Does one's professional lens create similarities more dominant than culture; and does English evoke responses significantly different from those of one's native language. ICE emerged from Cultureactive when validity and reliability research issues became noteworthy. Known as the ABC research team, Adair, Buchan and Chen [1] and [2] capitalized upon both Hall's low context/high context communication tool and Triandis' model of subjective culture to result in the theoretical underpinnings for ICE. This conceptual reconfiguration is also grounded in the works of Trompenaars, Holtgraves, Hampden-Turner, Thomas and Kilman, Yamagishi, and Bearden, Money and Nevins [3], [11], [20], [22] and [24]. ICE implementation strategies include the employment of Myers Briggs typologies. The contribution of this paper is the celebration of the first year of ICE [InterCultural Edge], and its far-reaching ramifications. Previous research streams have underscored global similarities and differences among cultures, and a previous paper [23] established that cross-professional rather than cross-cultural differences are more paramount in assessing communication differences. This study employs Cultureactive and the LMR model, noting that business

Global Existence Analysis of Cross-Diffusion Population Systems for Multiple Species

Science.gov (United States)

Chen, Xiuqing; Daus, Esther S.; Jüngel, Ansgar

2018-02-01

The existence of global-in-time weak solutions to reaction-cross-diffusion systems for an arbitrary number of competing population species is proved. The equations can be derived from an on-lattice random-walk model with general transition rates. In the case of linear transition rates, it extends the two-species population model of Shigesada, Kawasaki, and Teramoto. The equations are considered in a bounded domain with homogeneous Neumann boundary conditions. The existence proof is based on a refined entropy method and a new approximation scheme. Global existence follows under a detailed balance or weak cross-diffusion condition. The detailed balance condition is related to the symmetry of the mobility matrix, which mirrors Onsager's principle in thermodynamics. Under detailed balance (and without reaction) the entropy is nonincreasing in time, but counter-examples show that the entropy may increase initially if detailed balance does not hold.

Global Crossing optical infrastructure is critical part of next-generation Internet

CERN Multimedia

2002-01-01

"Global Crossing announced today that it has signed a contract with the Netherlands National Research Network, SURFnet, to provide multi-Gigabit wavelength connectivity between Amsterdam's NetherLight and Switzerland's CERN in Geneva for use in tests that optimise how research networks are used" (1 page).

Cross-species comparison of biological themes and underlying genes on a global gene expression scale in a mouse model of colorectal liver metastasis and in clinical specimens

Directory of Open Access Journals (Sweden)

Schirmacher Peter

2008-09-01

Full Text Available Abstract Background Invasion-related genes over-expressed by tumor cells as well as by reacting host cells represent promising drug targets for anti-cancer therapy. Such candidate genes need to be validated in appropriate animal models. Results This study examined the suitability of a murine model (CT26/Balb/C of colorectal liver metastasis to represent clinical liver metastasis specimens using a global gene expression approach. Cross-species similarity was examined between pure liver, liver invasion, tumor invasion and pure tumor compartments through overlap of up-regulated genes and gene ontology (GO-based biological themes on the level of single GO-terms and of condensed GO-term families. Three out of four GO-term families were conserved in a compartment-specific way between the species: secondary metabolism (liver, invasion (invasion front, and immune response (invasion front and liver. Among the individual GO-terms over-represented in the invasion compartments in both species were "extracellular matrix", "cell motility", "cell adhesion" and "antigen presentation" indicating that typical invasion related processes are operating in both species. This was reflected on the single gene level as well, as cross-species overlap of potential target genes over-expressed in the combined invasion front compartments reached up to 36.5%. Generally, histopathology and gene expression correlated well as the highest single gene overlap was found to be 44% in syn-compartmental comparisons (liver versus liver whereas cross-compartmental overlaps were much lower (e.g. liver versus tumor: 9.7%. However, single gene overlap was surprisingly high in some cross-compartmental comparisons (e.g. human liver invasion compartment and murine tumor invasion compartment: 9.0% despite little histolopathologic similarity indicating that invasion relevant genes are not necessarily confined to histologically defined compartments. Conclusion In summary, cross

Radioimmunoassays for cyclic AMP cross-react with phosphodiesterase inhibitors and buffer components

NARCIS (Netherlands)

Sinha, B; Semmler, J; Haen, E; Moeller, J; Endres, S

We addressed the issue of cross-reactivity of several commonly used phosphodiesterase inhibitors with radioimmunoassays for cyclic AMP, after we had observed a considerably high cross-reactivity with a noncommercial antibody. Theophylline, pentoxifylline, penthydroxifylline (BL 194), albifylline

Allergy to fish parvalbumins: studies on the cross-reactivity of allergens from 9 commonly consumed fish.

Science.gov (United States)

Van Do, Thien; Elsayed, Said; Florvaag, Erik; Hordvik, Ivar; Endresen, Curt

2005-12-01

Fish-hypersensitive patients can probably tolerate some fish species while being allergic to others. To determine the allergenic cross-reactivity between 9 commonly edible fish: cod, salmon, pollack, mackerel, tuna, herring, wolffish, halibut, and flounder. Sera from 10 patients allergic to fish and rabbit antisera against 3 parvalbumins (Gad c 1, Sal s 1, and The c 1) were used. Cross-reactivity was investigated by SDS/PAGE and IgE immunoblotting, IgG ELISA, IgE ELISA inhibition, and skin prick test (SPT). Cod (Gad c 1), salmon (Sal s 1), pollack (The c 1), herring, and wolffish share antigenic and allergenic determinants as shown by immunoblots and IgE ELISA, whereas halibut, flounder, tuna, and mackerel displayed lowest cross-reactivities. The highest mean IgE ELISA inhibition percent of 10 sera was obtained by Gad c 1, followed by The c 1, herring, Sal s 1, wolffish, halibut, flounder, tuna, and mackerel with the least inhibition. Nine of the 10 patients showed positive SPT to cod, salmon, and pollack; 8 patients reacted to recombinant (r) Sal s 1. Positive SPTs to rGad c 1 and rThe c 1 were demonstrated in 1 patient. Gad c 1, Sal s 1, The c 1, herring, and wolffish contained the most potent cross-reacting allergens, whereas halibut, flounder, tuna, and mackerel were the least allergenic in the current study. The latter could probably be tolerated by some of the tested patients.

ASTER Global DEM contribution to GEOSS demonstrates open data sharing

Science.gov (United States)

Sohre, T.; Duda, K. A.; Meyer, D. J.; Behnke, J.; Nasa Esdis Lp Daac

2010-12-01

across all the GEOSS Societal Benefit areas was shown. The release of the global tiled research-grade DEM resulted in a significant increase in demand for ASTER elevation models, and increased awareness of related products. No cost access to these data has also promoted new applications of remotely sensed data, increasing their use across the full range of the GEOSS societal benefit areas. In addition, the simplified data access and greatly expanded pool of users resulted in a number of suggestions from researchers in many disciplines for possible enhancements to future versions of the ASTER GDEM. The broad distribution of the product can be directly attributed to the adoption of fundamental GEOSS data sharing principles, which are directed toward expanded access by minimizing time delay and cost, thus facilitating data use for education, research, and a range of other applications. The ASTER GDEM demonstrated the need and user demand for an improved global DEM product as well as the added benefit of not only “full and open” distribution, but “free and open” distribution.

Cross-correlation Doppler global velocimetry (CC-DGV)

Science.gov (United States)

Cadel, Daniel R.; Lowe, K. Todd

2015-08-01

A flow velocimetry method, cross-correlation Doppler global velocimetry (CC-DGV), is presented as a robust, simplified, and high dynamic range implementation of the Doppler global/planar Doppler velocimetry technique. A sweep of several gigahertz of the vapor absorption spectrum is used for each velocity sample, with signals acquired from both Doppler-shifted scattered light within the flow and a non-Doppler shifted reference beam. Cross-correlation of these signals yields the Doppler shift between them, averaged over the duration of the scan. With presently available equipment, velocities from 0 ms-1 to over 3000 ms-1 can notionally be measured simultaneously, making the technique ideal for high speed flows. The processing routine is shown to be robust against large changes in the vapor pressure of the iodine cell, benefiting performance of the system in facilities where ambient conditions cannot be easily regulated. Validation of the system was performed with measurements of a model wind turbine blade boundary layer made in a 1.83 m by 1.83 m subsonic wind tunnel for which laser Doppler velocimetry (LDV) measurements were acquired alongside the CC-DGV results. CC-DGV uncertainties of ±1.30 ms-1, ±0.64 ms-1, and ±1.11 ms-1 were determined for the orthogonal stream-wise, transverse-horizontal, and transverse-vertical velocity components, and root-mean-square deviations of 2.77 ms-1 and 1.34 ms-1 from the LDV validation results were observed for Reynolds numbers of 1.5 million and 2 million, respectively. Volumetric mean velocity measurements are also presented for a supersonic jet, with velocity uncertainties of ±4.48 ms-1, ±16.93 ms-1, and ±0.50 ms-1 for the orthogonal components, and self-validation done by collapsing the data with a physical scaling.

Antigenic Cross-reactivity among Haemonchus contortus, Oesophagostomum columbianum and Trichuris ovis of Goat

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Ruma JAS

2016-12-01

Full Text Available Background: Cross antigenicity is the major problem in developing a reliable tool for immunodiagnosis and immunoprophylaxis of parasitic diseases. Mixed infection due to different types of gastrointestinal parasites is more common than single species infection under field condition.Methods: The present study was undertaken to detect antigenic cross-reactivity among Haemonchus contortus, Oesophagostomum columbianum and Trichuris ovis of goats by SDS-PAGE and western blot analysis using hyperimmune sera (HIS rose in rabbit separately against the antigens of the three nematode species.Results: Thirteen, 16 and 14 polypeptides in crude somatic antigen (CSAg of H. contortus (CSAg-Hc, O. columbianum (CSAg-Oc and T. ovis (CSAg-To, respectively, were resolved in SDS PAGE analyses. It was revealed that 54 kDa peptide was shared by H.contortus and O. columbianum, whereas 47 kDa peptide was shared by O. columbianum and T. ovis. Western blot analyses revealed that three immunogenic polypeptides (MW 54, 49 and 42 kDa in CSAg-Hc, five in CSAg-Oc (54, 47, 44, 38 and 35.5 kDa and CSAg-To and five polypeptides (90, 51, 47, 39.5 and 31 kDa in CSAg-To cross-reacted with the heterologous HIS. Four species-specific immunoreactive polypeptides (92, 85, 65 and 39 kDa of H. contortus and two (72 & 26 kDa in O. columbianum were also identified in the study. Conclusion: The shared polypeptides and species-specific polypeptides might be evaluated as protective antigen and subsequently exploitation for developing immunodiagnostic and for immunoprophylactic tools of for these common nematode species. 

Antigenic Cross-reactivity among Haemonchus contortus, Oesophagostomum columbianum and Trichuris ovis of Goat.

Science.gov (United States)

Jas, Ruma; Ghosh, Joydeb; DAS, Kinsuk

2016-01-01

Cross antigenicity is the major problem in developing a reliable tool for immunodiagnosis and immunoprophylaxis of parasitic diseases. Mixed infection due to different types of gastrointestinal parasites is more common than single species infection under field condition. The present study was undertaken to detect antigenic cross-reactivity among Haemonchus contortus, Oesophagostomum columbianum and Trichuris ovis of goats by SDS-PAGE and western blot analysis using hyperimmune sera (HIS) rose in rabbit separately against the antigens of the three nematode species. Thirteen, 16 and 14 polypeptides in crude somatic antigen (CSAg) of H. contortus (CSAg-Hc), O. columbianum (CSAg-Oc) and T. ovis (CSAg-To), respectively, were resolved in SDS PAGE analyses. It was revealed that 54 kDa peptide was shared by H.contortus and O. columbianum , whereas 47 kDa peptide was shared by O. columbianum and T. ovis . Western blot analyses revealed that three immunogenic polypeptides (MW 54, 49 and 42 kDa) in CSAg-Hc, five in CSAg-Oc (54, 47, 44, 38 and 35.5 kDa) and CSAg-To and five polypeptides (90, 51, 47, 39.5 and 31 kDa) in CSAg-To cross-reacted with the heterologous HIS. Four species-specific immunoreactive polypeptides (92, 85, 65 and 39 kDa) of H. contortus and two (72 & 26 kDa) in O. columbianum were also identified in the study. The shared polypeptides and species-specific polypeptides might be evaluated as protective antigen and subsequently exploitation for developing immunodiagnostic and for immunoprophylactic tools of for these common nematode species.

Evaluation of the Cross-reactivity of Antidrug Antibodies to CT-P13 and Infliximab Reference Product (Remicade): An Analysis Using Immunoassays Tagged with Both Agents.

Science.gov (United States)

Reinisch, Walter; Jahnsen, Jørgen; Schreiber, Stefan; Danese, Silvio; Panés, Julián; Balsa, Alejandro; Park, Won; Kim, JiSoo; Lee, Jee Un; Yoo, Dae Hyun

2017-06-01

During two pivotal clinical trials of the infliximab biosimilar CT-P13 (PLANETAS and PLANETRA), antidrug antibodies (ADAs) and neutralising antibodies (NAbs) were detected in the sera of patients treated with CT-P13 and the reference product (RP; Remicade). The aim was to assess the comparability of Remicade- and CT-P13-tagged immunoassays for the detection of ADAs and NAbs using data from these trials, in order to determine the cross-reactivity of CT-P13 and RP ADAs. Sera from patients with rheumatoid arthritis and ankylosing spondylitis were analysed using an electrochemiluminescence (ECL) bridging assay or Gyros immunoassay, tagged with Remicade or CT-P13 at screening, weeks 14, 30 and 54, and the end of study visit. NAb titre was compared at screening and weeks 14 and 30. The proportion of cross-reactive samples was determined and an inter-rater agreement analysis performed to assess the concordance of results between assays. In PLANETAS, 93.1% (94/101) of RP ADA-positive samples and 93.0% (93/100) of RP NAb-positive samples cross-reacted with CT-P13; 99.0% (103/104) of CT-P13 ADA-positive and 98.0% (98/100) of CT-P13 NAb-positive samples cross-reacted with the RP. In PLANETRA, 94.7% (426/450) of RP ADA-positive samples and 94.3% (415/440) of RP NAb-positive samples cross-reacted with CT-P13, and 96.6% (458/474) of CT-P13 ADA-positive and 96.4% (452/469) of CT-P13 NAb-positive samples cross-reacted with the RP. In both studies, there was strong agreement in outcome between assays at all post-screening time points (PLANETAS: Cohen's κ 0.89-0.98 for ADA, 0.86-0.98 for NAb; PLANETRA: 0.92-0.94 for both ADA and NAb, all p PLANETAS: Spearman's ρ 0.73 and 0.74, respectively; PLANETRA: 0.61 and 0.72, respectively; all p < 0.001). This study has demonstrated that ADAs and NAbs against CT-P13 and RP are cross-reactive, indicating that CT-P13 and RP share immunodominant epitopes.

Factors Impacting Knowledge Sharing

DEFF Research Database (Denmark)

Schulzmann, David; Slepniov, Dmitrij

The purpose of this paper is to examine various factors affecting knowledge sharing at the R&D center of a Western MNE in China. The paper employs qualitative methodology and is based on the action research and case study research techniques. The findings of the paper advance our understanding...... about factors that affect knowledge sharing. The main emphasis is given to the discussion on how to improve knowledge sharing in global R&D organizations....

Mapping the epitopes of a neutralizing antibody fragment directed against the lethal factor of Bacillus anthracis and cross-reacting with the homologous edema factor.

Directory of Open Access Journals (Sweden)

Philippe Thullier

Full Text Available The lethal toxin (LT of Bacillus anthracis, composed of the protective antigen (PA and the lethal factor (LF, plays an essential role in anthrax pathogenesis. PA also interacts with the edema factor (EF, 20% identity with LF to form the edema toxin (ET, which has a lesser role in anthrax pathogenesis. The first recombinant antibody fragment directed against LF was scFv 2LF; it neutralizes LT by blocking the interaction between PA and LF. Here, we report that scFv 2LF cross-reacts with EF and cross-neutralizes ET, and we present an in silico method taking advantage of this cross-reactivity to map the epitope of scFv 2LF on both LF and EF. This method identified five epitope candidates on LF, constituted of a total of 32 residues, which were tested experimentally by mutating the residues to alanine. This combined approach precisely identified the epitope of scFv 2LF on LF as five residues (H229, R230, Q234, L235 and Y236, of which three were missed by the consensus epitope candidate identified by pre-existing in silico methods. The homolog of this epitope on EF (H253, R254, E258, L259 and Y260 was experimentally confirmed to constitute the epitope of scFv 2LF on EF. Other inhibitors, including synthetic molecules, could be used to target these epitopes for therapeutic purposes. The in silico method presented here may be of more general interest.

Globalization and Cross-Border Labor Organizing

Directory of Open Access Journals (Sweden)

Ralph Armbruster

2015-08-01

Full Text Available The globalization of the world economy has opened up new possibilities for cross-border labor organizing. In fact, several U.S. unions are working together with unions from Mexico, Honduras, Guatemala, the Dominican Republic, Japan, South Korea, and many European nations. For example, over the last several years, UNITE (Union of Needletrades, Industrial, and Textile Employees, the AFL-CIO, and the international garment workers trade secretariat have worked directly with maquiladora workers in Honduras and the Dominican Republic. These efforts led to the formation of several labor unions and the first contracts ever negotiated in the maquiladoras in the Dominican Republic. In addition, labor rights and solidarity organizations, like the Campaign for Labor Rights, Witness for Peace, and the US/Guatemala Labor Education Project (US/GLEP, along with many other groups, have also played key roles in the formation of maquiladora unions in Nicaragua and Guatemala.

Primary biliary cirrhosis is characterized by IgG3 antibodies cross-reactive with the major mitochondrial autoepitope and its Lactobacillus mimic.

Science.gov (United States)

Bogdanos, Dimitrios-Petrou; Baum, Harold; Okamoto, Manabu; Montalto, Paolo; Sharma, Umesh C; Rigopoulou, Eirini I; Vlachogiannakos, John; Ma, Yun; Burroughs, Andrew K; Vergani, Diego

2005-08-01

The serological hallmark of primary biliary cirrhosis (PBC) is the presence of pyruvate dehydrogenase complex E2 subunit (PDC-E2) antimitochondrial antibodies (AMAs). Anti-PDC-E2 antibodies cross-react specifically with mycobacterial hsp65, and we have demonstrated that the motif SxGDL[ILV]AE shared by PDC-E2(212-226) and hsp's is a cross-reactive target. Having found that this same motif is present only in beta-galactosidase of Lactobacillus delbrueckii (BGAL LACDE), we hypothesized that this homology would also lead to cross-reactivity. The mimics were tested via ELISA for reactivity and competitive cross-reactivity using sera from 100 AMA-positive and 23 AMA-negative PBC patients and 190 controls. An Escherichia coli (ECOLI) PDC-E2 mimic that has been pathogenetically linked to PBC but lacks this motif has been also tested. Anti-BGAL(266-280) LACDE antibodies were restricted to AMA-positive patients (54 of 95, 57%) and belonged to immunoglobulin (Ig) G3. Of the 190 controls, 22 (12%; P ECOLI PDC-E2 reactivity was virtually absent. BGAL(266-280)/PDC-E2(212-226) reactivity of the IgG3 isotype was found in 52 (52%) AMA-positive PBC patients but in only 1 of the controls (P ECOLI PDC-E2 mimics. In conclusion, IgG3 antibodies to BGAL LACDE cross-react with the major mitochondrial autoepitope and are characteristic of PBC.

Study of transport and micro-structural properties of magnesium di-boride strand under react and bend mode and bend and react mode

International Nuclear Information System (INIS)

Kundu, Ananya; Das, Subrat Kumar; Bano, Anees; Pradhan, Subrata

2015-01-01

I-V characterization of commercial multi-filamentary Magnesium Di-Boride (MgB 2 ) wire of diameter 0.83 mm were studied in cryocooler based self-field characterization system under both react and bent mode and bent and react mode for a range of temperature 6 K - 25 K. This study is of practical technical relevance where the heat treatment of the superconducting wire makes the sample less flexible for winding in magnet and in other applications. There are limited reported data, available on degradation of MgB 2 wire with bending induced strain in react and wind and wind and react method. In the present work the bending diameter were varied from 80 mm to 20 mm in the interval of 10 mm change of bending diameter and for each case critical current (Ic) of the strand is measured for the above range of temperature. An ETP copper made customized sample holder for mounting the MgB 2 strand was fabricated and is thermally anchored to the cooling stage of the cryocooler. It is seen from the experimental data that in react and bent mode the critical current degrades from 105 A to 87 A corresponding to bending diameter of 80 mm and 20 mm respectively. The corresponding bending strain was analytically estimated and compared with the simulation result. It is also observed that in react and bent mode, the degradation of the transport property of the strand is less as compared to react and bent mode. For bent and react mode in the same sample, the critical current (Ic) was measured to be ∼145 A at 15 K for bending diameter of 20 mm. Apart from studying the bending induced strain on MgB 2 strand, the tensile test of the strand at RT was carried out. The electrical characterizations of the samples were accompanied by the microstructure analyses of the bent strand to examine the bending induced degradation in the grain structure of the strand. All these experimental findings are expected to be used as input to fabricate prototype MgB 2 based magnet. (author)

Cross-Cultural Context, Content, and Design: Development of Courses in Global Topics Serving International Students

Science.gov (United States)

Van Hook, Steven R.

2011-01-01

This research was conducted in the development of courses for students from multiple nations at two California universities, applying cross-cultural tactics in course content and design. The paper examines the evolution of courses in Global Issues and Global Economics, including the theoretical foundations of socioeconomic development, how those…

Reacting plasma project at IPP Japan

International Nuclear Information System (INIS)

Miyahara, A.; Momota, H.; Hamada, Y.; Kawamura, K.; Akimune, H.

1981-01-01

Contributed papers of the seminar on burning plasma held at UCLA are collected. Paper on ''overview of reacting plasma project'' described aim and philosophy of R-Project in Japan. Paper on ''Burning plasma and requirements for design'' gave theoretical aspect of reacting plasma physics while paper on ''plasma container, heating and diagnostics'' treated experimental aspect. Tritium handling is essential for the next step experiment; therefore, paper on ''Tritium problems in burning plasma experiments'' took an important part of this seminar. As appendix, paper on ''a new type of D - ion source using Si-semiconductor'' was added because such an advanced R and D work is essential for R-Project. (author)

The Art Institution in a Globalizing World

NARCIS (Netherlands)

Gielen, Pascal

2010-01-01

How do oclassicalo big art institutions (museums, the ballet, the opera, symphony orchestras) react to phenomena of globalization such as migration flows, the odenationalizationo of artistic movements, the enormous growth of the number of artists, the trend of a global cultural branding of cities,

Knowledge sharing through social media: Investigating trends and technologies in a global marketing and advertising research company

Directory of Open Access Journals (Sweden)

Dina Adamovic

2012-02-01

Full Text Available Background: The purpose of this study was to investigate social media technology trends in Nielsen – a global information and measurement company – and to establish how these technologies can help the company to create a knowledge-sharing culture.Objective: The objective of this study was to investigate trends in knowledge-sharing technologies in Nielsen.Method: The researchers distributed semi-structured questionnaires to a sample of employees in Nielsen’s Television Audience Measurement Department. They also conducted interviews with specific employees in this department to gain a better understanding of employees’ attitudes toward, and perceptions of, the use of social media tools for creating a knowledgesharing culture at Nielsen. The researchers validated the data to see whether it could support the research and used triangulation to create a holistic view of the data they received from the questionnaires.Results: The findings of the study revealed that respondents had a positive attitude to sharing knowledge with one another through using social media tools. However, some respondents thought that technology, in general, was ‘the tree of good and evil’. The survey findings showed that Nielsen did have social media tools. However, not all employees were aware of these tools or were willing to use the tools to share knowledge. This study highlighted the possible advantages of the social media for sharing knowledge and how Nielsen could use the tools more widely.Conclusion: In order for a knowledge sharing culture to thrive at Nielsen, its employees need to engage more with social media tools in their business practices. 

Antigenic Cross-Reactivity Anti-Birtoxin Antibody against Androctonus crassicauda Venom

Directory of Open Access Journals (Sweden)

SuhandanAdigüzel Van-Zoelen

2015-10-01

Full Text Available Background: Antivenom is still widely used in the treatment of envenomation as there are no vaccines or other effective agents available against animal venoms. Recently, neurotoxins named birtoxin family have been described from Parabuthus transvaalicus and Androctonus crassicauda. The aim of the present study was to test the antibirtoxinantibodies for their ability to neutralize the lethal effects of A. crassicauda scorpion venom.Methods: SDS-PAGE and Western blotting used the presence of components from A. crassicauda and P.transvaalicus scorpion venoms and to determine the degree of cross-reactivity. The Minimum Lethal Dose (MLD of venom was assessed by subcutaneously (sc injections in mice.Results: The MLD of the A. crassicauda venom was 35 μg/ 20g mouse by sc injection route. Western blotting showed the presence of components from A. crassicauda and P. transvaalicus scorpion venoms strongly cross react with the A. crassicauda antivenom. However, Western blotting of the A. crassicauda scorpion venom using the Refik Saydam Public Health Agency (RSPHA generated antibody showed that not all the venom components cross reacted with the anti-birtoxin antibody. The antibodies only cross reacted with components falling under the 19 kDa protein size of A. crassicauda venom.Conclusion: The bioassays and Western blotting of A. crassicauda venom with the anti-birtoxin antibodies produced against a synthetic peptide showed that these antibodies cross reacted but did not neutralize the venom of A. crassicauda.

A Hilbert Space Geometric Representation of Shared Awareness and Joint Decision Making

Science.gov (United States)

Canan, Mustafa

2017-01-01

Two people in the same situation may ascribe very different meanings to their experiences. They will form different awareness, reacting differently to shared information. Various factors can give rise to this behavior. These factors include, but are not limited to, prior knowledge, training, biases, cultural factors, social factors, team vs.…

Therapeutic preparations of IVIg contain naturally occurring anti-HLA-E antibodies that react with HLA-Ia (HLA-A/-B/-Cw) alleles.

Science.gov (United States)

Ravindranath, Mepur H; Terasaki, Paul I; Pham, Tho; Jucaud, Vadim; Kawakita, Satoru

2013-03-14

The US Food and Drug Administration approved intravenous immunoglobulin (IVIg), extracted from the plasma of thousands of blood donors, for removing HLA antibodies (Abs) in highly sensitized patients awaiting organ transplants. Since the blood of healthy individuals has HLA Abs, we tested different IVIg preparations for reactivity to HLA single antigen Luminex beads. All preparations showed high levels of HLA-Ia and -Ib reactivity. Since normal nonalloimmunized males have natural antibodies to the heavy chains (HCs) of HLA antigens, the preparations were then tested against iBeads coated only with intact HLA antigens. All IVIg preparations varied in level of antibody reactivity to intact HLA antigens. We raised monoclonal Abs against HLA-E that mimicked IVIg's HLA-Ia and HLA-Ib reactivity but reacted only to HLA-I HCs. Inhibition experiments with synthetic peptides showed that HLA-E shares epitopes with HLA-Ia alleles. Importantly, depleting anti-HLA-E Abs from IVIg totally eliminated the HLA-Ia reactivity of IVIg. Since anti-HLA-E mAbs react with HLA-Ia, they might be useful in suppressing HLA antibody production, similar to the way anti-RhD Abs suppress production. At the same time, anti-HLA-E mAb, which reacts only to HLA-I HCs, is unlikely to produce transfusion-related acute lung injury, in contrast to antibodies reacting to intact-HLA.

Fusion Kalman filtration with k-step delay sharing pattern

Directory of Open Access Journals (Sweden)

Duda Zdzisław

2015-09-01

Full Text Available A fusion hierarchical state filtration with k−step delay sharing pattern for a multisensor system is considered. A global state estimate depends on local state estimates determined by local nodes using local information. Local available information consists of local measurements and k−step delay global information - global estimate sent from a central node. Local estimates are transmitted to the central node to be fused. The synthesis of local and global filters is presented. It is shown that a fusion filtration with k−step delay sharing pattern is equivalent to the optimal centralized classical Kalman filtration when local measurements are transmitted to the center node and used to determine a global state estimate. It is proved that the k−step delay sharing pattern can reduce covariances of local state errors.

Effect of skin barrier disruption on immune responses to topically applied cross-reacting material, CRM(197), of diphtheria toxin.

Science.gov (United States)

Godefroy, S; Peyre, M; Garcia, N; Muller, S; Sesardic, D; Partidos, C D

2005-08-01

The high accessibility of the skin and the presence of immunocompetent cells in the epidermis makes this surface an attractive route for needle-free administration of vaccines. However, the lining of the skin by the stratum corneum is a major obstacle to vaccine delivery. In this study we examined the effect of skin barrier disruption on the immune responses to the cross-reacting material CRM(197), a nontoxic mutant of diphtheria toxin (DTx) that is considered as a vaccine candidate. Application of CRM(197), together with cholera toxin (CT), onto the tape-stripped skin of mice elicited antibody responses that had anti-DTx neutralizing activity. Vaccine delivery onto mildly ablated skin or intact skin did not elicit any detectable anti-CRM(197) antibodies. Mice immunized with CRM(197) alone onto the tape-stripped skin mounted a vigorous antigen-specific proliferative response. In contrast, the induction of cellular immunity after CRM(197) deposition onto mildly ablated or intact skin was adjuvant dependent. Furthermore, epidermal cells were activated and underwent apoptosis that was more pronounced when the stratum corneum was removed by tape stripping. Overall, these findings highlight the potential for transcutaneous delivery of CRM(197) and establish a correlation between the degree of barrier disruption and levels of antigen-specific immune responses. Moreover, these results provide the first evidence that the development of a transcutaneous immunization strategy for diphtheria, based on simple and practical methods to disrupt the skin barrier, is feasible.

T cell clones which share T cell receptor epitopes differ in phenotype, function and specificity

NARCIS (Netherlands)

Yssel, H.; Blanchard, D.; Boylston, A.; de Vries, J. E.; Spits, H.

1986-01-01

Recently, we described a monoclonal antibody (3D6) that reacts with the T cell receptor (Ti) of the T leukemic cell line HPB-ALL and that cross-reacts with 2-10% of the T cells of normal healthy individuals. In this study we report the establishment of T cell clones that are 3D6+ but that differ in

O-GlcNAc-specific antibody CTD110.6 cross-reacts with N-GlcNAc2-modified proteins induced under glucose deprivation.

Directory of Open Access Journals (Sweden)

Takahiro Isono

Full Text Available Modification of serine and threonine residues in proteins by O-linked β-N-acetylglucosamine (O-GlcNAc glycosylation is a feature of many cellular responses to the nutritional state and to stress. O-GlcNAc modification is reversibly regulated by O-linked β-N-acetylglucosamine transferase (OGT and β-D-N-acetylglucosaminase (O-GlcNAcase. O-GlcNAc modification of proteins is dependent on the concentration of uridine 5'-diphospho-N-acetylglucosamine (UDP-GlcNAc, which is a substrate of OGT and is synthesized via the hexosamine biosynthetic pathway. Immunoblot analysis using the O-GlcNAc-specific antibody CTD110.6 has indicated that glucose deprivation increases protein O-GlcNAcylation in some cancer cells. The mechanism of this paradoxical phenomenon has remained unclear. Here we show that the increased glycosylation induced by glucose deprivation and detected by CTD110.6 antibodies is actually modification by N-GlcNAc(2, rather than by O-GlcNAc. We found that this induced glycosylation was not regulated by OGT and O-GlcNAcase, unlike typical O-GlcNAcylation, and it was inhibited by treatment with tunicamycin, an N-glycosylation inhibitor. Proteomics analysis showed that proteins modified by this induced glycosylation were N-GlcNAc(2-modified glycoproteins. Furthermore, CTD110.6 antibodies reacted with N-GlcNAc(2-modified glycoproteins produced by a yeast strain with a ts-mutant of ALG1 that could not add a mannose residue to dolichol-PP-GlcNAc(2. Our results demonstrated that N-GlcNAc(2-modified glycoproteins were induced under glucose deprivation and that they cross-reacted with the O-GlcNAc-specific antibody CTD110.6. We therefore propose that the glycosylation status of proteins previously classified as O-GlcNAc-modified proteins according to their reactivity with CTD110.6 antibodies must be re-examined. We also suggest that the repression of mature N-linked glycoproteins due to increased levels of N-GlcNAc(2-modified proteins is a newly

Fungal decay resistance of wood reacted with phosphorus pentoxide-amine system

Science.gov (United States)

Hong-Lin Lee; George C. Chen; Roger M. Rowell

2004-01-01

Resistance of wood reacted in situ with phosphorus pentoxide-amine to the brown-rot fungus Gloeophyllum trabeum and white-rot fungus Trametes versicolor was examined. Wood reacted with either octyl, tribromo, or nitro derivatives were more resistant to both fungi. Threshold retention values of phosphoramide-reacted wood to white-rot fungus T. versicolor ranged from 2.9...

Brain development in the yellow fever mosquito Aedes aegypti: a comparative immunocytochemical analysis using cross-reacting antibodies from Drosophila melanogaster.

Science.gov (United States)

Mysore, Keshava; Flister, Susanne; Müller, Pie; Rodrigues, Veronica; Reichert, Heinrich

2011-12-01

Considerable effort has been directed towards understanding the organization and function of peripheral and central nervous system of disease vector mosquitoes such as Aedes aegypti. To date, all of these investigations have been carried out on adults but none of the studies addressed the development of the nervous system during the larval and pupal stages in mosquitoes. Here, we first screen a set of 30 antibodies, which have been used to study brain development in Drosophila, and identify 13 of them cross-reacting and labeling epitopes in the developing brain of Aedes. We then use the identified antibodies in immunolabeling studies to characterize general neuroanatomical features of the developing brain and compare them with the well-studied model system, Drosophila melanogaster, in larval, pupal, and adult stages. Furthermore, we use immunolabeling to document the development of specific components of the Aedes brain, namely the optic lobes, the subesophageal neuropil, and serotonergic system of the subesophageal neuropil in more detail. Our study reveals prominent differences in the developing brain in the larval stage as compared to the pupal (and adult) stage of Aedes. The results also uncover interesting similarities and marked differences in brain development of Aedes as compared to Drosophila. Taken together, this investigation forms the basis for future cellular and molecular investigations of brain development in this important disease vector. © Springer-Verlag 2011

Empowering Faculty to Develop and Share Global Knowledge

Science.gov (United States)

Harrison, David

2014-01-01

As colleges seek to increase global knowledge within its students, it is important that faculty members are also offered opportunities to increase their own knowledge of global issues. This chapter discusses faculty development models for seminars abroad and how these seminars encourage the development of unique global study programs.

What are the major global threats and impacts in marine environments? Investigating the contours of a shared perception among marine scientists from the bottom-up

DEFF Research Database (Denmark)

Boonstra, W.J.; Maj Ottosen, Katharina; Ferreira, Ana Sofia

2015-01-01

academics in marine science this article explores if a shared research agenda in relation to global change in marine environments exists. The analysis demonstrates that marine scientists across disciplines are largely in agreement on some common features of global marine change. Nevertheless, the analysis...... also highlights where natural and social scientists diverge in their assessment. The article ends discussing what these findings imply for further improvement of interdisciplinary marine science......Marine scientists broadly agree on which major processes influence the sustainability of marine environments worldwide. Recent studies argue that such shared perceptions crucially shape scientific agendas and are subject to a confirmation bias. Based on these findings a more explicit engagement...

A global water scarcity assessment under Shared Socio-economic Pathways – Part 1: Water use

Directory of Open Access Journals (Sweden)

N. Hanasaki

2013-07-01

Full Text Available A novel global water scarcity assessment for the 21st century is presented in a two-part paper. In this first paper, water use scenarios are presented for the latest global hydrological models. The scenarios are compatible with the socio-economic scenarios of the Shared Socio-economic Pathways (SSPs, which are a part of the latest set of scenarios on global change developed by the integrated assessment, the IAV (climate change impact, adaptation, and vulnerability assessment, and the climate modeling community. The SSPs depict five global situations based on substantially different socio-economic conditions during the 21st century. Water use scenarios were developed to reflect not only quantitative socio-economic factors, such as population and electricity production, but also key qualitative concepts such as the degree of technological change and overall environmental consciousness. Each scenario consists of five factors: irrigated area, crop intensity, irrigation efficiency, and withdrawal-based potential industrial and municipal water demands. The first three factors are used to estimate the potential irrigation water demand. All factors were developed using simple models based on a literature review and analysis of historical records. The factors are grid-based at a spatial resolution of 0.5° × 0.5° and cover the whole 21st century in five-year intervals. Each factor shows wide variation among the different global situations depicted: the irrigated area in 2085 varies between 2.7 × 106 and 4.5 × 106 km2, withdrawal-based potential industrial water demand between 246 and 1714 km3 yr−1, and municipal water between 573 and 1280 km3 yr−1. The water use scenarios can be used for global water scarcity assessments that identify the regions vulnerable to water scarcity and analyze the timing and magnitude of scarcity conditions.

Responding to excessive alcohol consumption in third-level (REACT): a study protocol.

Science.gov (United States)

Davoren, Martin P; Calnan, Susan; Mulcahy, Judith; Lynch, Emily; Perry, Ivan J; Byrne, Michael

2018-05-11

Problem alcohol use is an ongoing, worldwide phenomenon of considerable concern. Throughout the past 20 years, national policies have noted the importance of students when tackling alcohol consumption. Considering alcohol is a multifaceted issue, a multi-component response is required to combat its excessive use. This protocol sets out the approach used for developing, implementing and evaluating the REACT (Responding to Excessive Alcohol Consumption in Third-level) Programme. This evaluation will provide the evidence base for programme development, implementation and improvement. Stage one involved defining the multi-component intervention. This was developed following a systematic review of existing literature and a Delphi-consensus workshop involving university students, staff and relevant stakeholders. Following this, the programme is being implemented across the Higher Education sector in Ireland. A number of Higher Education Institutes have declined the invitation to participate in the programme. These institutions will act as control sites. Each intervention site will have a steering committee whose membership will include a mix of students and academic and student service staff. This steering committee will report to the REACT research team on the implementation of mandatory and optional action points at local sites. An online cross-sectional study at baseline and two-years post intervention will be utilised to determine the impact of the REACT programme. The impact assessment will focus on (1) whether the intervention has reduced alcohol consumption among third-level students (2); whether the programme altered students attitudes toward alcohol and (3) whether the programme has decreased the second-hand effects associated with excessive consumption. Finally, qualitative research will focus on factors influencing the take-up and implementation of this programme as well as students' views on the initiative. Alcohol consumption has remained on the policy

A Visual Approach to Investigating Shared and Global Memory Behavior of CUDA Kernels

KAUST Repository

Rosen, Paul

2013-01-01

We present an approach to investigate the memory behavior of a parallel kernel executing on thousands of threads simultaneously within the CUDA architecture. Our top-down approach allows for quickly identifying any significant differences between the execution of the many blocks and warps. As interesting warps are identified, we allow further investigation of memory behavior by visualizing the shared memory bank conflicts and global memory coalescence, first with an overview of a single warp with many operations and, subsequently, with a detailed view of a single warp and a single operation. We demonstrate the strength of our approach in the context of a parallel matrix transpose kernel and a parallel 1D Haar Wavelet transform kernel. © 2013 The Author(s) Computer Graphics Forum © 2013 The Eurographics Association and Blackwell Publishing Ltd.

A Visual Approach to Investigating Shared and Global Memory Behavior of CUDA Kernels

KAUST Repository

Rosen, Paul

2013-06-01

We present an approach to investigate the memory behavior of a parallel kernel executing on thousands of threads simultaneously within the CUDA architecture. Our top-down approach allows for quickly identifying any significant differences between the execution of the many blocks and warps. As interesting warps are identified, we allow further investigation of memory behavior by visualizing the shared memory bank conflicts and global memory coalescence, first with an overview of a single warp with many operations and, subsequently, with a detailed view of a single warp and a single operation. We demonstrate the strength of our approach in the context of a parallel matrix transpose kernel and a parallel 1D Haar Wavelet transform kernel. © 2013 The Author(s) Computer Graphics Forum © 2013 The Eurographics Association and Blackwell Publishing Ltd.

The REACT Project

DEFF Research Database (Denmark)

Bloch, Paul; Blystad, Astrid; Byskov, Jens

decisions; and the provision of leadership and the enforcement of conditions. REACT - "REsponse to ACcountable priority setting for Trust in health systems" is an EU-funded five-year intervention study, which started in 2006 testing the application and effects of the AFR approach in one district each...... selected disease and programme interventions and services, within general care and on health systems management. Efforts to improve health sector performance have not yet been satisfactory, and adequate and sustainable improvements in health outcomes have not been shown. Priority setting in health systems...... improvements to health systems performance discussed....

How preschoolers react to norm violations is associated with culture.

Science.gov (United States)

Gampe, Anja; Daum, Moritz M

2018-01-01

Children from the age of 3years understand social norms as such and enforce these norms in interactions with others. Differences in parental and institutional education across cultures make it likely that children receive divergent information about how to act in cases of norm violations. In the current study, we investigated whether cultural values are associated with the ways in which children react to norm violations. We tested 80 bicultural 3-year-olds with a norm enforcement paradigm and analyzed their reactions to norm violations. The reactions were correlated to the children's parental cultural values using the Global Leadership and Organizational Behavior Effectiveness (GLOBE) scales, and these results show that parental culture was associated with children's reactions to norm violations. The three strongest correlations were found for institutional collectivism, performance orientation, and assertiveness. Copyright © 2017 Elsevier Inc. All rights reserved.

Cross-cultural nursing research.

Science.gov (United States)

Suhonen, Riitta; Saarikoski, Mikko; Leino-Kilpi, Helena

2009-04-01

International cross-cultural comparative nursing research is considered important for the advancement of nursing knowledge offering a global perspective for nursing. Although this is recognised in policy statements and quality standards, international comparative studies are rare in database citations. To highlight the need for cross-cultural comparative research in nursing and to share some of the insights gained after conducting three international/cross-cultural comparative studies. These are: an examination of patients' autonomy, privacy and informed consent in nursing interventions BIOMED 1998-2001, the ICProject International Patient Study 2002-2006 and the Ethical Codes in Nursing (ECN) project 2003-2005. There are three critical issues raised here for discussion from the international cross-cultural studies. These are: the planning and formulating of an international study, the conduct of cross-cultural research including the implementation of rigorous data collection and analysis and the reporting and implementing the results. International and cross-cultural nursing research is powerful tool for the improvement of clinical nursing practise, education and management and advancement of knowledge. Such studies should be carried out in order to improve European evidence based health care development in which the patients' perspective plays an important part in the evaluation and benchmarking of services.

Antibodies against Clonorchis sinensis LDH could cross-react with LDHB localizing on the plasma membrane of human hepatocarcinoma cell SMMC-7721 and induce apoptosis.

Science.gov (United States)

Song, Tianzhang; Gan, Wenjia; Chen, Jintao; Huang, Lilin; Yin, Hongling; He, Tailong; Huang, Huaiqiu; Hu, Xuchu

2016-04-01

Lactate dehydrogenase (LDH) is a terminal enzyme in anaerobic glycolytic pathway. It widely exists in various organisms and is in charge of converting the glycolysis product pyruvic acid to lactic acid. Most parasites, including Clonorchis sinensis, predominantly depend on glycolysis to provide energy. Bioinformatic analysis predicts that the LDHs from many species have more than one transmembrane region, suggesting that it may be a membrane protein. C. sinensis LDH (CsLDH) has been confirmed as a transmembrane protein mainly located in the tegument. The antibodies against CsLDH can inhibit the worm's energy metabolism, kill the worm, and may have the same effects on human cancer cells. In this study, we cloned and characterized human LDHA (HsLDHA), HsLDHB, and CsLDH. Semi-quantitative real-time RCP showed that HsLDHB only existed in hepatocarcinoma cell SMMC-7721. Confocal microscopy and Western blot experiments revealed that HsLDHB was localized in the plasma membrane of SMMC-7721 cells, and the antibodies against CsLDH could cross-react with it. This cross-reaction could inhibit the enzymatic activity of HsLDHB. The cancer cells co-cultured with anti-CsLDH sera showed a significant decrease in cell proliferation rate and increases in caspase 9 and reactive oxygen species (ROS) levels. Therefore, anti-CsLDH antibodies can induce the apoptosis of cancer cells SMMC-7721 and may serve as a new tool to inhibit tumor.

Experimental investigation of a reacting transverse jet in a high pressure oscillating vitiated crossflow

Science.gov (United States)

Fugger, Christopher A.

near a pressure node of the 1st axial combustor mode, where the dominant flowfield fluctuations are a time-varying crossflow velocity. For the non-reacting jets, the nominal jet-to-crossflow momentum flux ratio is 19. For the reacting jets, the nominal jet-to-crossflow momentum flux ratio is 6. Two cross sectional planes parallel to the jet injection wall are investigated: 1 and 2.7 jet diameters from the jet injection wall. The combustor crossflow high frequency wall mounted pressure data is given for each test case. The velocity and OH-PLIF data is presented as instantaneous snapshots, time and phase averaged flowfields, modal decompositions using Proper Orthogonal Decomposition and Dynamic Mode Decomposition, and a jet cycle analysis relative to the crossflow acoustic cycle. Analysis of the five test cases shows that the jet cross sectional velocity and OH-PLIF dynamics display a multitude of dynamics. These are often organized into shear layer dynamics and wake dynamics, but are not mutually exclusive. For large unsteady crossflow velocity oscillations at the 1st axial combustor mode, both dynamics show strong organization at the unsteady crossflow frequency. Deciphering these dynamics is complicated by the fact that the ostensible jet response to the time-varying crossflow is a time-varying jet penetration. This drives the jet toward and away from the jet injection wall. These motions are perpendicular to the laser sheet and creates significant out-of-plane motions. The amplitude of crossflow unsteadiness appears to play a role in the sharpness of the wake dynamics. For the non-reacting cases, the wake dynamics are strong and dominant spectral features in the flowfield. For the reacting cases, the wake dynamics are spectrally distinct in the lower amplitude crossflow unsteadiness case, but a large unsteady amplitude crossflow appears to suppress the spectral bands in the frequency range corresponding to wake vortex dynamics.

Water within the Shared Socioeconomic Pathways: Constraints and the Impact on Future Global Change Scenarios

Science.gov (United States)

Graham, N. T.; Hejazi, M. I.; Davies, E. G.; Calvin, K. V.; Kim, S. H.; Miralles-Wilhelm, F.

2017-12-01

The Shared Socioeconomic Pathways (SSPs) represent the next generation of future global change scenarios and their inclusion in the Coupled Model Intercomparison Project Phase 6 (CMIP6) scenarios reinforces the importance of a complete understanding of the SSPs. This study uses the Global Change Assessment Model (GCAM) to investigate the effects of limited water supplies on future withdrawals at regional and water basin scales across all SSPs in combination with various climate mitigation scenarios. Water supply is calculated using a global hydrologic model and water data from five ISI-MIP models across the four RCP scenarios. When water constraints are incorporated, our results show that water withdrawals are reduced by as much as 40% across all SSP scenarios without climate policies. As climate policies are imposed and become more stringent, water withdrawals increase in regions already affected by water stress in order to allow for greater biomass production. The results of this research show the importance of including water resource constraints within the SSP scenarios for establishing water withdrawal scenarios under a wide range of scenarios including different climate policies. The results will also provide data products - such as gridded land use and water demand estimates - of potential interest to the impact, adaptation, and vulnerability community following the SSP scenarios.

'Reacting to the unknown': experiencing the first birth at home or in hospital in Australia.

Science.gov (United States)

Dahlen, Hannah G; Barclay, Lesley; Homer, Caroline S E

2010-08-01

to explore the experiences of a small group of first-time mothers giving birth at home or in hospital. a grounded theory methodology was used. Data were generated from in-depth interviews with women in their own homes. Sydney, Australia. 19 women were interviewed. Seven women who gave birth for the first time in a public hospital and seven women who gave birth for the first time at home were interviewed, and their experiences were contrasted with two mothers who gave birth for the first time in a birth centre, one mother who gave birth for the first time in a private hospital and two women who had given birth more than once. these women shared common experiences of giving birth as 'novices'. Regardless of birth setting, they were all 'reacting to the unknown'. As they entered labour, the women chose different levels of responsibility for their birth. They also readjusted their expectations when the reality of labour occurred, reacted to the 'force' of labour, and connected or disconnected from the labour and eventually the baby. knowing that first-time mothers, irrespective of birth setting, are essentially 'reacting to the unknown' as they negotiate the experience of birth, could alter the way in which care is provided and increase the sensitivity of midwives to women's needs. Most importantly, midwives need to be aware of the need to help women adjust their expectations during labour and birth. Identifying the 'novice' status of first-time mothers also better explains previous research that reports unrealistic expectations and fear that may be associated with first-time birthing. Crown Copyright 2008. Published by Elsevier Ltd. All rights reserved.

A constitutive theory of reacting electrolyte mixtures

Science.gov (United States)

Costa Reis, Martina; Wang, Yongqi; Bono Maurizio Sacchi Bassi, Adalberto

2013-11-01

A constitutive theory of reacting electrolyte mixtures is formulated. The intermolecular interactions among the constituents of the mixture are accounted for through additional freedom degrees to each constituent of the mixture. Balance equations for polar reacting continuum mixtures are accordingly formulated and a proper set of constitutive equations is derived with basis in the Müller-Liu formulation of the second law of thermodynamics. Moreover, the non-equilibrium and equilibrium responses of the reacting mixture are investigated in detail by emphasizing the inner and reactive structures of the medium. From the balance laws and constitutive relations, the effects of molecular structure of constituents upon the fluid flow are studied. It is also demonstrated that the local thermodynamic equilibrium state can be reached without imposing that the set of independent constitutive variables is time independent, neither spatially homogeneous nor null. The resulting constitutive relations presented throughout this work are of relevance to many practical applications, such as swelling of clays, developing of bio and polymeric membranes, and use of electrorheological fluids in industrial processes. The first author acknowledges financial support from National Counsel of Technological and Scientific Development (CNPq) and German Academic Exchange Service (DAAD).

A Cross-Country Analysis Regarding the Impact of the Recent Global Crisis on the Banking Sector

Directory of Open Access Journals (Sweden)

Angela ROMAN

2011-06-01

Full Text Available The current global crisis has had tremendous effects on the banking sectors from the new EU member countries. In this context it becomes important to analyse how the crisis has affected these banking systems and also how the monetary authorities from these countries have reacted in such an adverse situation in order to ensure the macro-stability and the re-launch of the lending process. In order to achieve this, firstly we have reviewed the academic literature on this subject, in order to avoid any overlap in our research and to ensure the originality of our undertaking. Secondly, using a quantitative approach, we have comparatively analysed the effects of the economic and financial crisis on the banking systems from our panel.

Assessing future reactive nitrogen inputs into global croplands based on the shared socioeconomic pathways

Science.gov (United States)

Mogollón, J. M.; Lassaletta, L.; Beusen, A. H. W.; van Grinsven, H. J. M.; Westhoek, H.; Bouwman, A. F.

2018-04-01

Reactive nitrogen (N) inputs in agriculture strongly outpace the outputs at the global scale due to inefficiencies in cropland N use. While improvement in agricultural practices and environmental legislation in developed regions such as Western Europe have led to a remarkable increase in the N use efficiency since 1985, this lower requirement for reactive N inputs via synthetic fertilizers has yet to occur in many developing and transition regions. Here, we explore future N input requirements and N use efficiency in agriculture for the five shared socioeconomic pathways. Results show that under the most optimistic sustainability scenario, the global synthetic fertilizer use in croplands stabilizes and even shrinks (85 Tg N yr‑1 in 2050) regardless of the increase in crop production required to feed the larger estimated population. This scenario is highly dependent on projected increases in N use efficiency, particularly in South and East Asia. In our most pessimistic scenario, synthetic fertilization application rates are expected to increase almost threefold by 2050 (260 Tg N yr‑1). Excepting the sustainability scenario, all other projected scenarios reveal that the areal N surpluses will exceed acceptable limits in most of the developing regions.

Radioimmunoassay for abscisic acid: properties of cross-reacting polar metabolites

Energy Technology Data Exchange (ETDEWEB)

Le Page-Degivry, M.; Bulard, C. (Faculte des Sciences et des Techniques, 06 - Nice (France))

When the radioimmunoassay developed for abscisic acid (ABA) estimation was applied to a plant extract, results appeared overestimated. Purification by thin-layer chromatography established that ABA in its free and alkali-hydrolysable forms constituted only a small part of the immunoreactive material. The major source of the cross-reactivity was a group of polar metabolites, poorly soluble in ether and well recovered by ethyl acetate and butanol. These immunoreactive metabolites were compared with polar metabolites already described in experiments where (/sup 14/C)ABA was fed to plant tissue, particularly with recently identified glucosides of ABA and dihydrophaseic acid.

Cross-Border Higher Education: Global and Local Tensions within Competition and Economic Development

Science.gov (United States)

Owens, Taya L.; Lane, Jason E.

2014-01-01

In this chapter, the authors explore various types of cross-border higher education, considering equity and quality issues within these developments. With a particular focus on international branch campuses, the authors discuss the ways in which global competition for knowledge and economic development interact with tensions at the local level.

Why Have Labour Markets Reacted to the Global Crisis in Different Ways?

Directory of Open Access Journals (Sweden)

Kwiatkowski Eugeniusz

2016-12-01

Full Text Available This paper aims to identify the effects of the global crisis on employment and unemployment in the EU countries and indicate factors which may explain the differentiated response of labour markets to this crisis.

Extension of a semi-implicit shock-capturing algorithm for 3-D fully coupled, chemically reacting flows in generalized coordinates

International Nuclear Information System (INIS)

Shinn, J.L.; Yee, H.C.; Uenishi, K.; NASA, Ames Research Center, Moffett Field, CA; Vigyan Research Associates, Inc., Hampton, VA)

1987-01-01

A semiimplicit high-resolution shock-capturing method for multidimensional systems of hyperbolic conservation laws with stiff source terms has been developed by Yee and Shinn (1987). The goal of this work is to extend this method to solve the three-dimensional fully coupled Navier-Stokes equations for a hypersonic chemically reacting flow in generalized coordinates. In this formulation, the global continuity equation was replaced by all the species continuity equations. The shock-capturing technique is a second-order-accurate, symmetric total-variation-diminishing method which accounts fully and directly for the coupling among the fluid and all the species. To verify the current approach, it was implemented into an existing computer code which contained the MacCormack method. Test results for a five-species reacting flow are shown to be oscillation-free around the shock, and the time spent per iteration only doubles when compared to the result using classical way of supplying numerical dissipation. The extra computation is more than justified by the elimination of spurious oscillation and nonlinear instability associated with the classical shock-capturing schemes in computing hypersonic reacting flows. 27 references

Three-dimensional reacting shock–bubble interaction

NARCIS (Netherlands)

Diegelmann, Felix; Hickel, S.; Adams, Nikolaus A.

2017-01-01

We investigate a reacting shock–bubble interaction through three-dimensional numerical simulations with detailed chemistry. The convex shape of the bubble focuses the shock and generates regions of high pressure and temperature, which are sufficient to ignite the diluted stoichiometric

Poverty and Shared Prosperity 2016 : Taking on Inequality

OpenAIRE

World Bank Group

2016-01-01

Poverty and Shared Prosperity 2016 is the first of an annual flagship report that will inform a global audience comprising development practitioners, policy makers, researchers, advocates, and citizens in general with the latest and most accurate estimates on trends in global poverty and shared prosperity. This edition will also document trends in inequality and identify recent country experiences that have been successful in reducing inequalities, provide key lessons from those experien...

Forging a global community for science and innovation

CERN Document Server

CERN Bulletin

2010-01-01

This week, CERN is launching the CERN Global Network, which responds to a real need for us to keep in touch, to share our knowledge and expertise, and to build on the fantastic resource of the CERN community broadly defined. Here at CERN, we pride ourselves on the cross fertilization of ideas that occurs when people from around the world come together for a common goal. The Network extends that to our alumni and to our partners in academia, commerce and industry, allowing expertise to be shared among all its members. The CERN Global Network is open to anyone who works or has worked at or with CERN at any time. You don’t get much more inclusive than that. In an increasingly competitive world, knowledge transfer is vitally important for an organization like CERN. The primary outcome of our basic science is knowledge, but what use is knowledge if it’s confined to a select few? The people who drew up the CERN Convention over half a century ago saw the importance of transferring knowledge...

Position paper of the EAACI: food allergy due to immunological cross-reactions with common inhalant allergens.

Science.gov (United States)

Werfel, T; Asero, R; Ballmer-Weber, B K; Beyer, K; Enrique, E; Knulst, A C; Mari, A; Muraro, A; Ollert, M; Poulsen, L K; Vieths, S; Worm, M; Hoffmann-Sommergruber, K

2015-09-01

In older children, adolescents, and adults, a substantial part of all IgE-mediated food allergies is caused by cross-reacting allergenic structures shared by inhalants and foods. IgE stimulated by a cross-reactive inhalant allergen can result in diverse patterns of allergic reactions to various foods. Local, mild, or severe systemic reactions may occur already after the first consumption of a food containing a cross-reactive allergen. In clinical practice, clinically relevant sensitizations are elucidated by skin prick testing or by the determination of specific IgE in vitro. Component-resolved diagnosis may help to reach a diagnosis and may predict the risk of a systemic reaction. Allergy needs to be confirmed in cases of unclear history by oral challenge tests. The therapeutic potential of allergen immunotherapy with inhalant allergens in pollen-related food allergy is not clear, and more placebo-controlled studies are needed. As we are facing an increasing incidence of pollen allergies, a shift in sensitization patterns and changes in nutritional habits, and the occurrence of new, so far unknown allergies due to cross-reactions are expected. © 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Large Eddy Simulation of Spatially Developing Turbulent Reacting Shear Layers with the One-Dimensional Turbulence Model

Science.gov (United States)

Hoffie, Andreas Frank

model. The chemical reaction is simulated with a global single-step, second-order equilibrium reaction with an Arrhenius reaction rate. The two benchmark cases of constant density reacting and variable density non-reacting shear layers used to determine ODT parameters yield perfect agreement with regards to first and second-order flow statistics as well as shear layer growth rate. The variable density non-reacting shear layer also serves as a testing case for the LES-ODT model to simulate passive scalar mixing. The variable density, reacting shear layer cases only agree reasonably well and indicate that more work is necessary to improve variable density coupling of ODT and LES. The disagreement is attributed to the fact that the ODT filtered density is kept constant across the Runge-Kutta steps. Furthermore, a more in-depth knowledge of large scale and subgrid turbulent kinetic energy (TKE) spectra at several downstream locations as well as TKE budgets need to be studied to obtain a better understanding about the model as well as about the flow under investigation. The local Reynolds number based on the one-percent thickness at the exit is Redelta ≈ 5300, for the constant density reacting and for the variable density non-reacting case. For the variable density reacting shear layer, the Reynolds number based on the 1% thickness is Redelta ≈ 2370. The variable density reacting shear layers show suppressed growth rates due to density variations caused by heat release. This has also been reported in literature. A Lewis number parameter study is performed to extract non-unity Lewis number effects. An increase in the Lewis number leads to a further suppression of the growth rate, however to an increase spread of second-order flow statistics. Major focus and challenge of this work is to improve and advance the three-dimensional coupling of the one-dimensional ODT domains while keeping the solution correct. This entails major restructuring of the model. The turbulent

Combining discrete equations method and upwind downwind-controlled splitting for non-reacting and reacting two-fluid computations

International Nuclear Information System (INIS)

Tang, K.

2012-01-01

When numerically investigating multiphase phenomena during severe accidents in a reactor system, characteristic lengths of the multi-fluid zone (non-reactive and reactive) are found to be much smaller than the volume of the reactor containment, which makes the direct modeling of the configuration hardly achievable. Alternatively, we propose to consider the physical multiphase mixture zone as an infinitely thin interface. Then, the reactive Riemann solver is inserted into the Reactive Discrete Equations Method (RDEM) to compute high speed combustion waves represented by discontinuous interfaces. An anti-diffusive approach is also coupled with RDEM to accurately simulate reactive interfaces. Increased robustness and efficiency when computing both multiphase interfaces and reacting flows are achieved thanks to an original upwind downwind-controlled splitting method (UDCS). UDCS is capable of accurately solving interfaces on multi-dimensional unstructured meshes, including reacting fronts for both deflagration and detonation configurations. (author)

Measurements of non-reacting and reacting flow fields of a liquid swirl flame burner

Science.gov (United States)

Chong, Cheng Tung; Hochgreb, Simone

2015-03-01

The understanding of the liquid fuel spray and flow field characteristics inside a combustor is crucial for designing a fuel efficient and low emission device. Characterisation of the flow field of a model gas turbine liquid swirl burner is performed by using a 2-D particle imaging velocimetry(PIV) system. The flow field pattern of an axial flow burner with a fixed swirl intensity is compared under confined and unconfined conditions, i.e., with and without the combustor wall. The effect of temperature on the main swirling air flow is investigated under open and non-reacting conditions. The result shows that axial and radial velocities increase as a result of decreased flow density and increased flow volume. The flow field of the main swirling flow with liquid fuel spray injection is compared to non-spray swirling flow. Introduction of liquid fuel spray changes the swirl air flow field at the burner outlet, where the radial velocity components increase for both open and confined environment. Under reacting condition, the enclosure generates a corner recirculation zone that intensifies the strength of radial velocity. The reverse flow and corner recirculation zone assists in stabilizing the flame by preheating the reactants. The flow field data can be used as validation target for swirl combustion modelling.

‘Useful, usable and used’: Sustaining an Australian model of cross-faculty service learning by concentrating on shared value creation

Directory of Open Access Journals (Sweden)

Lisa Andersen

2017-06-01

Full Text Available In recent decades, partnerships between community-based organisations and universities through service-learning programs have proliferated, reflected in an equally energetic growth in the research literature on process, evaluation, benefits and lessons learned. As an example of student experiential education through community engagement, service learning’s potential to contribute to students, community partners and the university is well recognised, although the research has tended to focus on benefits to students rather than the value in engagement for the community sector. UTS Shopfront Community Program is a cross-university initiative that has successfully facilitated curricular service learning in multiple disciplines for 20 years at an Australian university, leading to the completion of more than 1000 community projects. In examining this program, this article aims to describe both a sustainable, generative partnership model for creating shared value and, through analysis of 10 years of evaluation data, define what value is created for community partners and students through this project work. Key components in enabling a shared-value approach include: community-initiated projects based on need; a dedicated cross-university program and an assigned project coordinator; the engagement of faculty expertise through students with developed skills in appropriately structured courses; and community ownership of outcomes. Ongoing challenges include: scoping ‘student-ready’ briefs; managing risk, commitment and workload; designing coursework structures to deliver shared value; and achieving the ‘Holy Grail’ of transdisciplinarity.

A global limit load solution for plates with surface cracks under combined end force and cross-thickness bending

International Nuclear Information System (INIS)

Lei Yuebao; Fox, Mike J.H.

2011-01-01

A global limit load solution for rectangular surface cracks in plates under combined end force and cross-thickness bending is derived, which allows any combination of positive/negative end force and positive/negative cross-thickness moment. The solution is based on the net-section plastic collapse concept and, therefore, gives limit load values based on the Tresca yielding criterion. Solutions for both cases with and without crack face contact are derived when whole or part of the crack is located in the compressive stress zone. From the solution, particular global limit load solutions for plates with extended surface cracks and through-thickness cracks under the same loading conditions are obtained. The solution is consistent with the limit load solution for surface cracks in plates under combined tension and positive bending due to Goodall and Webster and Lei when both the applied end force and bending moment are positive. The solution reduces to the limit load solution for plain plates under combined end force and cross-thickness bending when the crack vanishes. - Highlights: → A global limit load solution for plates with surface cracks in plates is derived. → Combined positive/negative end force and positive/negative cross-thickness moment are considered. → The solution is based on the net-section plastic collapse concept.

Musharakah Tijarah Cross-Border Financing: Concept, Structure and Salient Features

Directory of Open Access Journals (Sweden)

Sharullizuannizam Salehuddin

2016-12-01

Full Text Available Musharakah Tijarah Cross-Border Financing (“Product” is the product to enable the Bank to undertake project and contract cross-border financing activities or other identified business ventures on “pure” Joint Venture basis, using the underlying Islamic financing contract of Musharakah. Musharakah concept has a low market share of less than 2.5% in the overall existing Islamic financing products in Malaysia. This product encourages mobilization of idle capital / cash entities and thus provides a basis for economic cooperation between these organizations in the society. The product also is expected to inject greater prosper to the Bank’s overall performance and ultimately able to assist small time landowners in a big way through business risk sharing. Musharakah provides an alternative investment, which will cater for Islamic investors and partners, especially from GCC, who may have been reluctant to invest in conventional or current debt-based financing scheme. With Musharakah concept, the most preferred and globally accepted Islamic financing, this can attract these investors to participate on similar risk-sharing arrangements through the creation of Specific Investment Account (SIA or Islamic Syndication to back financing made into the Joint Venture.

Sentinel Gap basalt reacted in a temperature gradient

International Nuclear Information System (INIS)

Charles, R.W.; Bayhurst, G.K.

1983-01-01

Six basalt prisms were reacted in a controlled temperature gradient hydrothermal circulation system for two months. The prisms were centered at 72, 119, 161, 209, 270, and 310 0 C. Total pressure was 1/3 kbar. All prisms showed large weight loss: 5.5% to 14.9%. The matrix micropegmatite and natural nontronitic alteration reacted readily to clays at all temperatures. The first four prisms were coated with a calcium smectite, and the last two prisms were covered with discrete patches of potassium-rich phengite and alkali feldspar. The results indicated that clays may act as adsorbers of various ions

Sentinel Gap basalt reacted in a temperature gradient

International Nuclear Information System (INIS)

Charles, R.W.; Bayhurst, G.K.

1982-01-01

Six basalt prisms were reacted in a controlled temperature gradient hydrothermal circulation system for two months. The prisms are centered at 72, 119, 161, 209, 270, and 310 0 C. Total pressure is 1/3 kbar. All prisms show large weight loss: 5.5% to 14.9%. The matrix micropegmatite and natural nontronitic alteration readily reacts to clays at all temperatures. The first four prisms are coated with a Ca-smectite while the last two prisms are covered with discrete patches of K rich phengite and alkali feldspar. The clays may act as adsorbers of various ions

'Both parents should care for babies': A cross-sectional, cross-cultural comparison of adolescents' breastfeeding intentions, and the influence of shared-parenting beliefs.

Science.gov (United States)

Swanson, Vivien; Hannula, Leena; Eriksson, Linda; Wallin, Malin Häggkvist; Strutton, Joan

2017-06-29

Many young men and women expect to co-parent their newborn infant. This may have a positive or negative impact on decisions to breastfeed, which is an important health behaviour, influenced by cultural and psycho-social norms. We investigated the relationship between shared parenting, infant feeding beliefs and intentions in male and female (non-parent) adolescents, comparing Nordic countries (Sweden, Norway, Finland) with high breastfeeding rates with others with low rates (Scotland, USA). We utilised cross-sectional surveys of male and female adolescents (n = 1064, age 12-18) administered directly in schools or via the internet. We assessed attitudes to breast and formula feeding and shared parenting, using a Theory of Planned Behaviour framework, assessing beliefs, attitudes, norms and control as predictors of intention. Male and female adolescents' breastfeeding intentions varied in line with national cultural norms. Young people from Nordic countries (high breastfeeding rates) were significantly more likely to intend to breastfeed than those from Scotland or the USA (low breastfeeding rates). Positive beliefs about breastfeeding, norms and 'exposure' to breastfeeding and feeding confidence were consistently stronger in Nordic countries, whereas young people in Scotland had more positive beliefs, norms and 'exposure' to formula feeding. Differences in parenting beliefs, norms and confidence were less consistent. In logistic regression, cultural group, positive breastfeeding beliefs and exposure, norms, and shared parenting beliefs were significant predictors of breastfeeding feeding intention. Positive beliefs about shared parenting and equal gender norms were related to future breastfeeding intentions for female and male adolescents. Health education programmes for young people could encourage positive breastfeeding choices by considering how this would fit with young people's ideal parenting roles, and by emphasising benefits of complementary maternal and

Global Gene Expression Analysis of Cross-Protected Phenotype of Pectobacterium atrosepticum.

Directory of Open Access Journals (Sweden)

Vladimir Gorshkov

Full Text Available The ability to adapt to adverse conditions permits many bacterial species to be virtually ubiquitous and survive in a variety of ecological niches. This ability is of particular importance for many plant pathogenic bacteria that should be able to exist, except for their host plants, in different environments e.g. soil, water, insect-vectors etc. Under some of these conditions, bacteria encounter absence of nutrients and persist, acquiring new properties related to resistance to a variety of stress factors (cross-protection. Although many studies describe the phenomenon of cross-protection and several regulatory components that induce the formation of resistant cells were elucidated, the global comparison of the physiology of cross-protected phenotype and growing cells has not been performed. In our study, we took advantage of RNA-Seq technology to gain better insights into the physiology of cross-protected cells on the example of a harmful phytopathogen, Pectobacterium atrosepticum (Pba that causes crop losses all over the world. The success of this bacterium in plant colonization is related to both its virulence potential and ability to persist effectively under various stress conditions (including nutrient deprivation retaining the ability to infect plants afterwards. In our previous studies, we showed Pba to be advanced in applying different adaptive strategies that led to manifestation of cell resistance to multiple stress factors. In the present study, we determined the period necessary for the formation of cross-protected Pba phenotype under starvation conditions, and compare the transcriptome profiles of non-adapted growing cells and of adapted cells after the cross-protective effect has reached the maximal level. The obtained data were verified using qRT-PCR. Genes that were expressed differentially (DEGs in two cell types were classified into functional groups and categories using different approaches. As a result, we portrayed

Imaging of alpha(v)beta(3) expression by a bifunctional chimeric RGD peptide not cross-reacting with alpha(v)beta(5).

Science.gov (United States)

Zannetti, Antonella; Del Vecchio, Silvana; Iommelli, Francesca; Del Gatto, Annarita; De Luca, Stefania; Zaccaro, Laura; Papaccioli, Angela; Sommella, Jvana; Panico, Mariarosaria; Speranza, Antonio; Grieco, Paolo; Novellino, Ettore; Saviano, Michele; Pedone, Carlo; Salvatore, Marco

2009-08-15

To test whether a novel bifunctional chimeric peptide comprising a cyclic Arg-Gly-Asp pentapeptide covalently bound to an echistatin domain can discriminate alpha(v)beta(3) from alpha(v)beta(5) integrin, thus allowing the in vivo selective visualization of alpha(v)beta(3) expression by single-photon and positron emission tomography (PET) imaging. The chimeric peptide was preliminarily tested for inhibition of alpha(v)beta(3)-dependent cell adhesion and competition of 125I-echistatin binding to membrane of stably transfected K562 cells expressing alpha(v)beta(3) (Kalpha(v)beta(3)) or alpha(v)beta(5) (Kalpha(v)beta(5)) integrin. The chimeric peptide was then conjugated with diethylenetriaminepentaacetic acid and labeled with 111In for single-photon imaging, whereas a one-step procedure was used for labeling the full-length peptide and a truncated derivative, lacking the last five C-terminal amino acids, with 18F for PET imaging. Nude mice bearing tumors from Kalpha(v)beta(3), Kalpha(v)beta(5), U87MG human glioblastoma, and A431 human epidermoid cells were subjected to single-photon and PET imaging. Adhesion and competitive binding assays showed that the novel chimeric peptide selectively binds to alpha(v)beta(3) integrin and does not cross-react with alpha(v)beta(5). In agreement with in vitro findings, single-photon and PET imaging studies showed that the radiolabeled chimeric peptide selectively localizes in tumor xenografts expressing alphavbeta3 and fails to accumulate in those expressing alpha(v)beta(5) integrin. When 18F-labeled truncated derivative was used for PET imaging, alphavbeta3- and alpha(v)beta(5)-expressing tumors were visualized, indicating that the five C-terminal amino acids are required to differentially bind the two integrins. Our findings indicate that the novel chimeric Arg-Gly-Asp peptide, having no cross-reaction with alphavbeta5 integrin, allows highly selective alphavbeta3 expression imaging and monitoring.

Stereodynamics of Ne(3P2) reacting with Ar, Kr, Xe, and N2

Science.gov (United States)

Zou, Junwen; Gordon, Sean D. S.; Tanteri, Silvia; Osterwalder, Andreas

2018-04-01

Stereodynamics experiments of Ne(3P2) reacting with Ar, Kr, Xe, and N2 leading to Penning and associative ionization have been performed in a crossed molecular beam apparatus. A curved magnetic hexapole was used to state-select and polarize Ne(3P2) atoms which were then oriented in a rotatable magnetic field and crossed with a beam of Ar, Kr, Xe, or N2. The ratio of associative to Penning ionization was recorded as a function of the magnetic field direction for collision energies between 320 cm-1 and 500 cm-1. Reactivities are obtained for individual states that differ only in Ω, the projection of the neon total angular momentum vector on the inter-particle axis. The results are rationalized on the basis of a model involving a long-range and a short-range reaction mechanism. Substantially lower probability for associative ionization was observed for N2, suggesting that predissociation plays a critical role in the overall reaction pathway.

The lure of global branding.

Science.gov (United States)

Aaker, D A; Joachimsthaler, E

1999-01-01

As more and more companies begin to see the world as their market, brand builders look with envy upon those businesses that appear to have created global brands--brands whose positioning, advertising strategy, personality, look, and feel are in most respects the same from one country to another. Attracted by such high-profile examples of success, these companies want to globalize their own brands. But that's a risky path to follow, according to David Aaker and Erich Joachimsthaler. Why? Because creating strong global brands takes global brand leadership. It can't be done simply by edict from on high. Specifically, companies must use organizational structures, processes, and cultures to allocate brand-building resources globally, to create global synergies, and to develop a global brand strategy that coordinates and leverages country brand strategies. Aaker and Joachimsthaler offer four prescriptions for companies seeking to achieve global brand leadership. First, companies must stimulate the sharing of insights and best practices across countries--a system in which "it won't work here" attitudes can be overcome. Second, companies should support a common global brand-planning process, one that is consistent across markets and products. Third, they should assign global managerial responsibility for brands in order to create cross-country synergies and to fight local bias. And fourth, they need to execute brilliant brand-building strategies. Before stampeding blindly toward global branding, companies need to think through the systems they have in place. Otherwise, any success they achieve is likely to be random--and that's a fail-safe recipe for mediocrity.

Synthesis of 4-substituted tetrahydropyridines by cross-coupling of enol phosphates

DEFF Research Database (Denmark)

Larsen, U.S.; Martiny, L.; Begtrup, M.

2005-01-01

Enol phosphates, synthesized from 4-piperidone, react by palladium catalyzed cross-coupling with arylboronic acids and by iron and palladium catalyzed cross-coupling with Grignard reagents to give 4-substituted tetrahydropyridines. (c) 2005 Elsevier Ltd. All rights reserved....

Interorganizational Boundary Spanning in Global Software Development

DEFF Research Database (Denmark)

Søderberg, Anne-Marie; Romani, Laurence

, and which skills and competencies they draw on in their efforts to deal with emerging cross-cultural issues in a way that paves ground for developing a shared understanding and common platform for the client and vendor representatives. A framework of boundary spanning leadership practices is adapted...... to virtuality and cultural diversity. This paper, which draws on a case study of collaborative work in a global software development project, focuses on key boundary spanners in an Indian vendor company, who are responsible for developing trustful and sustainable client relations and coordinating complex...... projects across multiple cultures, languages, organisational boundaries, time zones and geographical distances. It looks into how these vendor managers get prepared for their complex boundary spanning work, which cross-cultural challenges they experience in their collaboration with Western clients...

Cross-layer shared protection strategy towards data plane in software defined optical networks

Science.gov (United States)

Xiong, Yu; Li, Zhiqiang; Zhou, Bin; Dong, Xiancun

2018-04-01

In order to ensure reliable data transmission on the data plane and minimize resource consumption, a novel protection strategy towards data plane is proposed in software defined optical networks (SDON). Firstly, we establish a SDON architecture with hierarchical structure of data plane, which divides the data plane into four layers for getting fine-grained bandwidth resource. Then, we design the cross-layer routing and resource allocation based on this network architecture. Through jointly considering the bandwidth resource on all the layers, the SDN controller could allocate bandwidth resource to working path and backup path in an economical manner. Next, we construct auxiliary graphs and transform the shared protection problem into the graph vertex coloring problem. Therefore, the resource consumption on backup paths can be reduced further. The simulation results demonstrate that the proposed protection strategy can achieve lower protection overhead and higher resource utilization ratio.

Fabrication of chemically cross-linked porous gelatin matrices.

Science.gov (United States)

Bozzini, Sabrina; Petrini, Paola; Altomare, Lina; Tanzi, Maria Cristina

2009-01-01

The aim of this study was to chemically cross-link gelatin, by reacting its free amino groups with an aliphatic diisocyanate. To produce hydrogels with controllable properties, the number of reacting amino groups was carefully determined. Porosity was introduced into the gelatin-based hydrogels through the lyophilization process. Porous and non-porous matrices were characterized with respect to their chemical structure, morphology, water uptake and mechanical properties. The physical, chemical and mechanical properties of the porous matrices are related to the extent of their cross-linking, showing that they can be controlled by varying the reaction parameters. Water uptake values (24 hours) vary between 160% and 200% as the degree of cross-linking increases. The flexibility of the samples also decreases by changing the extent of cross-linking. Young's modulus shows values between 0.188 KPa, for the highest degree, and 0.142 KPa for the lowest degree. The matrices are potential candidates for use as tissue-engineering scaffolds by modulating their physical chemical properties according to the specific application.

An experimental and numerical study of confined non-reacting and reacting turbulent jets to facilitate homogeneous combustion in industrial furnaces

Science.gov (United States)

Lee, Insu

Confined non-reacting turbulent jets are ideal for recirculating the hot flue gas back into the furnace from an external exhaust duct. Such jets are also used inside the furnace to internally entrain and recirculate the hot flue gas to preheat and dilute the reactants. Both internal and external implementation of confined turbulent jets increase the furnace thermal efficiency. For external implementation, depending on the circumstances, the exhaust gas flow may be co- or counter-flow relative to the jet flow. Inside the furnaces, fuel and air jets are injected separately. To create a condition which can facilitate near homogeneous combustion, these jets have to first mix with the burned gas inside the furnace and simultaneously being heated and diluted prior to combustion. Clearly, the combustion pattern and emissions from reacting confined turbulent jets are affected by jet interactions, mixing and entrainment of hot flue gas. In this work, the flow and mixing characteristics of a non-reacting and reacting confined turbulent jet are investigated experimentally and numerically. This work consists of two parts: (i) A study of flow and mixing characteristics of non-reacting confined turbulent jets with co- or counter-flowing exhaust/flue gas. Here the axial and radial distributions of temperature, velocity and NO concentration (used as a tracer gas) were measured. FLUENT was used to numerically simulate the experimental results. This work provides the basic understanding of the flow and mixing characteristics of confined turbulent jets and develops some design considerations for recirculating flue gas back into the furnace as expressed by the recirculation zone and the stagnation locations. (ii) Numerical calculations of near homogeneous combustion are performed for the existing furnace. The exact geometry of the furnace in the lab is used and the real dimensional boundary conditions are considered. The parameters such as air nozzle diameter (dair), fuel nozzle

Cross-National Applicability of a Parsimonious Measure of Acculturation to Global Consumer Culture.

Science.gov (United States)

Gupta, Nitin

2016-04-01

Durvasula and Lysonski's paper presented a shorter version of the Acculturation to Global Consumer Culture Scale (hereafter AGCC), which was developed by Cleveland and Laroche to address scarcity of measurements that determined how individuals acquired and became a part of the emerging global consumer culture. The following critique discusses a few concerns and three major shortcomings of the paper, including skewed sample frame and incorrect choice of countries for assessing cross-national applicability of the scale, not discussing the differences in the means of the seven distinct dimensions of AGCC across the four nations studied by the authors, and absence of any critical review of existing consumer acculturation scales vis-à-vis AGCC. © The Author(s) 2016.

Internationalization of product-service systems: Global, regional or national strategy?

OpenAIRE

Parry, G.; Bustinza, O. F.; Vendrell-Herrero, F.; O'Regan, N.

2016-01-01

This paper explores the validity of national, regional or global strategies in the provision of a music industry product service system. Quantitative analysis of cross-section data from over 70,000 respondents from 15 geographically spread countries identified a homogeneous group of so-called ‘Out of Touch’ consumers characterized by a shared attitude: they are interested in and have the money to purchase music, but no longer do so. The analysis ascertains if and how re-engaging this group in...

A Parallel Multiblock Structured Grid Method with Automated Interblocked Unstructured Grids for Chemically Reacting Flows

Science.gov (United States)

Spiegel, Seth Christian

An automated method for using unstructured grids to patch non- C0 interfaces between structured blocks has been developed in conjunction with a finite-volume method for solving chemically reacting flows on unstructured grids. Although the standalone unstructured solver, FVFLO-NCSU, is capable of resolving flows for high-speed aeropropulsion devices with complex geometries, unstructured-mesh algorithms are inherently inefficient when compared to their structured counterparts. However, the advantages of structured algorithms in developing a flow solution in a timely manner can be negated by the amount of time required to develop a mesh for complex geometries. The global domain can be split up into numerous smaller blocks during the grid-generation process to alleviate some of the difficulties in creating these complex meshes. An even greater abatement can be found by allowing the nodes on abutting block interfaces to be nonmatching or non-C 0 continuous. One code capable of solving chemically reacting flows on these multiblock grids is VULCAN, which uses a nonconservative approach for patching non-C0 block interfaces. The developed automated unstructured-grid patching algorithm has been installed within VULCAN to provide it the capability of a fully conservative approach for patching non-C0 block interfaces. Additionally, the FVFLO-NCSU solver algorithms have been deeply intertwined with the VULCAN source code to solve chemically reacting flows on these unstructured patches. Finally, the CGNS software library was added to the VULCAN postprocessor so structured and unstructured data can be stored in a single compact file. This final upgrade to VULCAN has been successfully installed and verified using test cases with particular interest towards those involving grids with non- C0 block interfaces.

Association between secondhand smoke exposure at home and cigarette gifting and sharing in Zhejiang, China: a repeat cross-sectional study.

Science.gov (United States)

Xu, Yue; Xu, ShuiYang; Wu, QingQing; Guo, YuJie

2016-03-03

The aims of the current study were to assess the prevalence of household cigarette gifting and sharing, and to evaluate the relationship between secondhand smoke (SHS) exposure, and cigarette gifting and sharing, in Zhejiang, China. A repeat cross-sectional design. 10 sites in 5 cities in Zhejiang, China. Two surveys were conducted with adults in Zhejiang, China, in 2010 (N=2112) and 2012 (N=2279), respectively. At both waves, the same questionnaire was used; respondents were asked questions on residence, number of family smokers, indoor smoking rules, household income and cigarette gifting and sharing. The findings revealed that more than half of respondents' families (54.50% in 2010, 52.79% in 2012) reported exposure to SHS. Many families (54.73% in 2010, 47.04% in 2012) shared cigarettes with others, and a minority (14.91% in 2010, 14.17% in 2012) reported their family giving cigarettes as a gift. There was a significant decrease in cigarette sharing from 2010 to 2012, irrespective of household with SHS exposure status; and the cigarette gifting was significantly decreased in household without SHS exposure. Compared to households without SHS exposure, the prevalence of cigarette gifting and sharing in households with SHS exposure was more obvious. Encouraging and promoting a smoke-free household environment is necessary to change public smoking customs in Zhejiang, China. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/

ReACT!: An Interactive Educational Tool for AI Planning for Robotics

Science.gov (United States)

Dogmus, Zeynep; Erdem, Esra; Patogulu, Volkan

2015-01-01

This paper presents ReAct!, an interactive educational tool for artificial intelligence (AI) planning for robotics. ReAct! enables students to describe robots' actions and change in dynamic domains without first having to know about the syntactic and semantic details of the underlying formalism, and to solve planning problems using…

Global Science Share: Connecting young scientists from developing countries with science writing mentors to strengthen and widen the international science community

Science.gov (United States)

Hasenkopf, C. A.

2012-12-01

Collaborative science in which scientists are able to form research questions based on the current body of scientific knowledge and get feedback from colleagues on their ideas and work is essential for pushing science forward. However, not all scientists are able to fully participate in the international science community. Scientists from developing countries can face barriers to communicating with the international community due to, among other issues: fewer scientists in their home country, difficulty in getting language-specific science writing training, fewer established pre-existing international collaborations and networks, and sometimes geographic isolation. These barriers not only result in keeping individual scientists from contributing their ideas, but they also slow down the progress of the scientific enterprise for everyone. Global Science Share (http://globalscienceshare.org/) is a new project, entering its pilot phase in Fall 2012, which will work to reduce this disparity by connecting young scientists and engineers from developing countries seeking to improve their technical writing with other scientists and engineers around the world via online collaborations. Scientist-volunteers act as mentors and are paired up with mentees according to their academic field and writing needs. The mentors give feedback and constructive technical and editorial criticisms on mentees' submitted pieces of writing through a four-step email discussion. Mentees gain technical writing skills, as well as make international connections with other scientists and engineers in fields related to their own. Mentors also benefit by gaining new international scientific colleagues and honing their own writing skills through their critiques. The Global Science Share project will begin its pilot phase by first inviting Mongolian science students to apply as mentees this fall. This abstract will introduce the Global Science Share program, present a progress report from its first

A radioimmunoassay for abscisic acid: properties of cross-reacting polar metabolites

International Nuclear Information System (INIS)

Le Page-Degivry, M.; Bulard, C.

1984-01-01

When the radioimmunoassay developed for abscisic acid (ABA) estimation was applied to a plant extract, results appeared overestimated. Purification by thin-layer chromatography established that ABA in its free and alkali-hydrolysable forms constituted only a small part of the immunoreactive material. The major source of the cross-reactivity was a group of polar metabolites, poorly soluble in ether and well recovered by ethyl acetate and butanol. These immunoreactive metabolites were compared with polar metabolites already described in experiments wher e [ 14 C]ABA was fed to plant tissue, particularly with recently identified glucosides of ABA and dihydrophaseic acid

Continuum-Kinetic Hybrid Framework for Chemically Reacting Flows

Data.gov (United States)

National Aeronautics and Space Administration — Predictive modeling of chemically reacting flows is essential for the design and optimization of future hypersonic vehicles. During atmospheric re-entry, complex...

Monoclonal antibodies (MAb) made against insect-derived metacyclic trypomastigotes (IMT) of Trypanosoma cruzi (TC) cross-react with other parasite forms

International Nuclear Information System (INIS)

Kirchhoff, L.V.; Gilliam, F.C.

1986-01-01

Considerable information has been generated in recent years about stage-specific surface membrane antigens of a number of protozoa, and this phenomenon has been observed among several stages of TC as well. However, little is known about the surface antigens of IMT, the true infective stage of TC, because of the difficulty of obtaining sufficient numbers of these organisms for analysis. The Tulahuen strain of TC was maintained in the reduviid vector Dipetalogaster maximus by repeated feeding on mice with high parasitemias. IMT collected with insect urine were irradiated (150 krad) and used to immunize a BALB/c mouse for hybridoma production. Supernatants were screened by immunofluorescence assay for the presence of IgG MAb that react with methanol-fixed IMT, epimastogotes (EPI) and culture-derived metacyclic trypomastigoes (CMT). Of 41 MAb obtained, 40 reacted with IMT, 37 with EPI and 38 with CMT. Four MAb immunoprecipitated radioiodinated proteins or protein conjugates of M/sub r/ 80, 72, 45 and 45 from lysates of 125 I surface-labeled EPI. These results indicate that, at least at the epitopic level, there is considerable overlap among IMT, EPI and CMT surface antigens. This finding suggests that analysis of surface proteins of the latter 2 parasite forms may lead to identification of molecules useful for vaccine development

Globalization of Health Service: Sharing of Best Practices in Perianesthesia Nursing Care, a Case Study of Cross-Border Institutional Collaboration.

Science.gov (United States)

Lee, Esther; Hamelin, Thomas; Daugherty, JoAnn

2018-04-01

Healthcare is a global concern among all nations and nursing is a global profession as evidenced by the flow of healthcare professionals across international boundaries. With English as the language of science and commerce and post-colonial influence in domestic healthcare practice and training, many former Anglo-speaking colonial settlements become parts of an expansive market for health human resources migration. The movement of health personnel mainly flows from low and medium income countries to high income countries to sustain their health systems. The resulting brain drain adversely impacts a source country's health system, leading the World Health Organization to declare global health migration as the biggest health threat of the 21st century. This report illustrates how an overseas health network achieves its goals of developing clinical and management excellence through an international exchange program. The provider institution also fulfills its mission of contributing to a more balanced, equitable and healthier world. Copyright © 2016 American Society of PeriAnesthesia Nurses. Published by Elsevier Inc. All rights reserved.

Importance of albumin in cross-reactivity among cat, dog and horse allergens.

Science.gov (United States)

Cabañas, R; López-Serrano, M C; Carreira, J; Ventas, P; Polo, F; Caballero, M T; Contreras, J; Barranco, P; Moreno-Ancillo, A

2000-01-01

Different allergenic proteins have been involved in cross-reactivity among animals. Albumins seem to be cross-sensitizing allergenic components. The aim of this study was to assess the importance of albumin as a cross-reactive allergen in patients sensitized to cat, dog and horse. One hundred and seventeen patients sensitized to cat were tested for IgE reactivity using skin prick tests and RAST assays with cat, dog and horse hair/dander extracts and their purified albumin extracts. RAST-inhibition studies were carried out to assess cross-reactivity among cat, dog and horse and among their purified albumins. It was found that 22% of patients exhibited specific IgE to cat albumin; 41% of patients sensitized to cat were also sensitized to dog and horse. Out of these patients, 21% had IgE to three albumins and 17% to two. Reciprocal inhibitions were observed among cat, dog and horse albumins and also among cat, dog and horse hair/dander extracts, using in the latter experiment sera from patients not sensitized to albumins. IgE binding to horse extract was inhibited 30% by its homologous albumin and IgE binding to cat and dog extracts in almost 15% by their respective albumins. It was concluded that albumins from these three animals share some epitopes that account for the cross-reactivity observed in around one-third of patients sensitized to cat, dog and horse. Nevertheless, more than 50% of specific IgE that cross-reacts among these three animals is directed to allergens other than albumin.

Position paper of the EAACI

DEFF Research Database (Denmark)

Werfel, T; Asero, R; Ballmer-Weber, B K

2015-01-01

In older children, adolescents, and adults, a substantial part of all IgE-mediated food allergies is caused by cross-reacting allergenic structures shared by inhalants and foods. IgE stimulated by a cross-reactive inhalant allergen can result in diverse patterns of allergic reactions to various f...

Study of Transport and Micro-structural properties of Magnesium Di-Boride Strand under react and bend mode and bend and react mode

International Nuclear Information System (INIS)

Kundu, Ananya; Kumar Das, Subrat; Bano, Anees; Pradhan, Subrata

2017-01-01

I-V characterization of commercial multi-filamentary Magnesium Di-Boride (MgB 2 ) wire of diameter 0.83 mm were studied in Cryocooler at self-field I-V characterization system under both react and bend mode and bend and react mode for a range of temperature 6 K - 25 K. This study is of practical technical relevance where the heat treatment of the superconducting wire makes the wire less flexible for winding in magnet and in other applications. In the present work the bending diameter was varied from 40 mm to 20 mm and for each case critical current (I c ) of the strand is measured for above range of temperature. A customized sample holder is fabricated and thermally anchored with the 2 nd cold stage of Cryocooler. It is observed from the measurement that the strand is more susceptible to degradation for react and bend cases. The transport measurement of the strand was accompanied by SEM analyses of bend samples. Also the tensile strength of the raw strands and the heat treated strands were carried out at room temperature in Universal Testing Machine (UTM) to have an estimate about the limiting winding tension value during magnet fabrication. (paper)

Demonstration of Hybrid DSMC-CFD Capability for Nonequilibrium Reacting Flow

Science.gov (United States)

2018-02-09

AFRL-RV-PS- TR-2018-0056 AFRL-RV-PS- TR-2018-0056 DEMONSTRATION OF HYBRID DSMC-CFD CAPABILITY FOR NONEQUILIBRIUM REACTING FLOW Thomas E...4. TITLE AND SUBTITLE Demonstration of Hybrid DSMC-CFD Capability for Nonequilibrium Reacting Flow 5a. CONTRACT NUMBER 5b. GRANT NUMBER FA9453-17-1...simulation codes. The models are based on new ab-intio rate data obtained using state -of-the-art potential energy surfaces for air species. A probability

Linking regional stakeholder scenarios and shared socioeconomic pathways: Quantified West African food and climate futures in a global context.

Science.gov (United States)

Palazzo, Amanda; Vervoort, Joost M; Mason-D'Croz, Daniel; Rutting, Lucas; Havlík, Petr; Islam, Shahnila; Bayala, Jules; Valin, Hugo; Kadi Kadi, Hamé Abdou; Thornton, Philip; Zougmore, Robert

2017-07-01

The climate change research community's shared socioeconomic pathways (SSPs) are a set of alternative global development scenarios focused on mitigation of and adaptation to climate change. To use these scenarios as a global context that is relevant for policy guidance at regional and national levels, they have to be connected to an exploration of drivers and challenges informed by regional expertise. In this paper, we present scenarios for West Africa developed by regional stakeholders and quantified using two global economic models, GLOBIOM and IMPACT, in interaction with stakeholder-generated narratives and scenario trends and SSP assumptions. We present this process as an example of linking comparable scenarios across levels to increase coherence with global contexts, while presenting insights about the future of agriculture and food security under a range of future drivers including climate change. In these scenarios, strong economic development increases food security and agricultural development. The latter increases crop and livestock productivity leading to an expansion of agricultural area within the region while reducing the land expansion burden elsewhere. In the context of a global economy, West Africa remains a large consumer and producer of a selection of commodities. However, the growth in population coupled with rising incomes leads to increases in the region's imports. For West Africa, climate change is projected to have negative effects on both crop yields and grassland productivity, and a lack of investment may exacerbate these effects. Linking multi-stakeholder regional scenarios to the global SSPs ensures scenarios that are regionally appropriate and useful for policy development as evidenced in the case study, while allowing for a critical link to global contexts.

An experimental study on downstream of the transition of the chemically reacting liquid round free jet

International Nuclear Information System (INIS)

Hong, S.D.; Sugii, Y.; Okamoto, K.; Madarame, H.

2002-01-01

An experimental study was conducted on the chemically reacting liquid round free jet, Laser Induced Fluorescence (LIF) technique was adopted to evaluate the diffusion width of the jet into liquid streams. In the fluid engineering, it is very important to evaluate the characteristics of reacting jet for the safety of the nuclear reactor. In this study, the jet profile of downstream region far away from the transition point was evaluated, providing comparisons between reacting and non-reacting jet case. The concentration of the jet solution was varied from 0.01 mol/L to 0.5 mol/L in reacting cases. In the downstream far away from the transition point, the jet profiles between reacting cases and non-reacting cases were visualized quite different. It was concluded that the chemical reaction affects the momentum diffusion of the jet in the downstream region. (author)

Questioning in Distributed Product Development Teams: Supporting Shared Understanding

DEFF Research Database (Denmark)

Cash, Philip; Ahmed-Kristensen, Saeema

2015-01-01

globally distributed NPD activities. Poor shared understanding can ultimately result in delays and rework. One major antecedent of shared understanding development is question asking. This work uses a quasiexperimental study to test the impact of questioning support on different types of distributed teams...

Coplanar asymmetric angles and symmetric energy sharing triple differential cross sections for 200 eV electron-impact ionization of Ar (3p)

International Nuclear Information System (INIS)

Ozer, Zehra N; Varol, Onur; Yavuz, Murat; Dogan, Mevlut; Amami, Sadek; Madison, Don

2015-01-01

We have measured triple differential cross sections (TDCSs) for electron-impact ionization of the 3p shell of Ar at 200 eV incident electron energy. The experiments have been performed in coplanar asymmetric energy sharing geometry. The experimental results are compared with the theoretical models of three body distorted wave (3DW) and distorted wave Born approximation (DWBA). (paper)

Conceptualizing the cross-cultural gaps in managing international aid: HIV/AIDS and TB project delivery in Southern Africa.

Science.gov (United States)

Jackson, Terence

2011-01-01

There appears to be a gap between the billions of dollars inputted into fighting HIV/AIDS and TB and outcomes. This in part can be attributed to the lack of attention in International Development to managing programmes and projects within complex levels of cross-cultural interactions. International Development often ignores management issues, yet Management Studies is left wanting through a lack of engagement with development issues including the fight against disease and poverty. This paper attempts to link these two disciplines towards mutual benefit, through a critical cross-cultural approach. It provides contextualization of international development policies/strategies; conceptualization of dominant paradigms; structural analysis of how a programme/project fits into the global governance structure; analysis of complexities and levels of cross-cultural interaction and their consequences and the process and implications of knowledge transfer across cultural distances. It concludes with implications for policy and practice, as well as what is needed from cross-disciplinary research. This includes how feedback loops can be strengthened from local to global, how indigenous knowledge may be better understood and integrated, how power relations within the global governance structure could be managed, how cross-cultural interaction could be better understood, and how knowledge transfer/sharing should be critically managed. Copyright © 2010 John Wiley & Sons, Ltd.

Cultural values and cross-cultural video consumption on YouTube

Science.gov (United States)

Macy, Michael

2017-01-01

Video-sharing social media like YouTube provide access to diverse cultural products from all over the world, making it possible to test theories that the Web facilitates global cultural convergence. Drawing on a daily listing of YouTube’s most popular videos across 58 countries, we investigate the consumption of popular videos in countries that differ in cultural values, language, gross domestic product, and Internet penetration rate. Although online social media facilitate global access to cultural products, we find this technological capability does not result in universal cultural convergence. Instead, consumption of popular videos in culturally different countries appears to be constrained by cultural values. Cross-cultural convergence is more advanced in cosmopolitan countries with cultural values that favor individualism and power inequality. PMID:28531228

Cultural values and cross-cultural video consumption on YouTube.

Science.gov (United States)

Park, Minsu; Park, Jaram; Baek, Young Min; Macy, Michael

2017-01-01

Video-sharing social media like YouTube provide access to diverse cultural products from all over the world, making it possible to test theories that the Web facilitates global cultural convergence. Drawing on a daily listing of YouTube's most popular videos across 58 countries, we investigate the consumption of popular videos in countries that differ in cultural values, language, gross domestic product, and Internet penetration rate. Although online social media facilitate global access to cultural products, we find this technological capability does not result in universal cultural convergence. Instead, consumption of popular videos in culturally different countries appears to be constrained by cultural values. Cross-cultural convergence is more advanced in cosmopolitan countries with cultural values that favor individualism and power inequality.

Cultural values and cross-cultural video consumption on YouTube.

Directory of Open Access Journals (Sweden)

Minsu Park

Full Text Available Video-sharing social media like YouTube provide access to diverse cultural products from all over the world, making it possible to test theories that the Web facilitates global cultural convergence. Drawing on a daily listing of YouTube's most popular videos across 58 countries, we investigate the consumption of popular videos in countries that differ in cultural values, language, gross domestic product, and Internet penetration rate. Although online social media facilitate global access to cultural products, we find this technological capability does not result in universal cultural convergence. Instead, consumption of popular videos in culturally different countries appears to be constrained by cultural values. Cross-cultural convergence is more advanced in cosmopolitan countries with cultural values that favor individualism and power inequality.

Investigating Solution Convergence in a Global Ocean Model Using a 2048-Processor Cluster of Distributed Shared Memory Machines

Directory of Open Access Journals (Sweden)

Chris Hill

2007-01-01

Full Text Available Up to 1920 processors of a cluster of distributed shared memory machines at the NASA Ames Research Center are being used to simulate ocean circulation globally at horizontal resolutions of 1/4, 1/8, and 1/16-degree with the Massachusetts Institute of Technology General Circulation Model, a finite volume code that can scale to large numbers of processors. The study aims to understand physical processes responsible for skill improvements as resolution is increased and to gain insight into what resolution is sufficient for particular purposes. This paper focuses on the computational aspects of reaching the technical objective of efficiently performing these global eddy-resolving ocean simulations. At 1/16-degree resolution the model grid contains 1.2 billion cells. At this resolution it is possible to simulate approximately one month of ocean dynamics in about 17 hours of wallclock time with a model timestep of two minutes on a cluster of four 512-way NUMA Altix systems. The Altix systems' large main memory and I/O subsystems allow computation and disk storage of rich sets of diagnostics during each integration, supporting the scientific objective to develop a better understanding of global ocean circulation model solution convergence as model resolution is increased.

Threshold policy for global games with noisy information sharing

KAUST Repository

Mahdavifar, Hessam; Beirami, Ahmad; Touri, Behrouz; Shamma, Jeff S.

2015-01-01

of information and show that such equilibrium strategies exist and are unique if the sharing of information happens over a sufficiently noisy environment. To show this result, we establish that if a threshold function is an equilibrium strategy, then it will be a

Improving Resilience to Emergencies through Advanced Cyber Technologies: the I-REACT project

Directory of Open Access Journals (Sweden)

Claudia Maltoni

2017-08-01

be equipped with essential tools for early warning and response. At the same time, private companies could leverage specific set of I-REACT components to improve their business, when linked to disaster management. Overall, I-REACT aims to be a European-wide contribution to build more secure and resilient societies to disasters.

Comparative health system performance in six middle-income countries: cross-sectional analysis using World Health Organization study of global ageing and health.

Science.gov (United States)

Alshamsan, Riyadh; Lee, John Tayu; Rana, Sangeeta; Areabi, Hasan; Millett, Christopher

2017-09-01

Objective To assess and compare health system performance across six middle-income countries that are strengthening their health systems in pursuit of universal health coverage. Design Cross-sectional analysis from the World Health Organization Study on global AGEing and adult health, collected between 2007 and 2010. Setting Six middle-income countries: China, Ghana, India, Mexico, Russia and South Africa. Participants Nationally representative sample of adults aged 50 years and older. Main outcome measures We present achievement against key indicators of health system performance across effectiveness, cost, access, patient-centredness and equity domains. Results We found areas of poor performance in prevention and management of chronic conditions, such as hypertension control and cancer screening coverage. We also found that cost remains a barrier to healthcare access in spite of insurance schemes. Finally, we found evidence of disparities across many indicators, particularly in the effectiveness and patient centredness domains. Conclusions These findings identify important focus areas for action and shared learning as these countries move towards achieving universal health coverage.

KEEFEKTIFAN STRATEGI REACT DITINJAU DARI PRESTASI BELAJAR, KEMAMPUAN PENYELESAIAN MASALAH, KONEKSI MATEMATIS, SELF EFFICACY

Directory of Open Access Journals (Sweden)

Runtyani Irjayanti Putri

2015-11-01

Full Text Available Penelitian ini bertujuan untuk: (1 mendeskripsikan keefektifan strategi pembelajaran REACT pada pembelajaran turunan fungsi ditinjau dari prestasi belajar matematika, kemampuan penyelesaian masalah matematis, kemampuan koneksi matematis, dan Self efficacy siswa SMA Negeri 4 Magelang, (2 menentukan strategi pembelajaran yang lebih efektif diantara strategi REACT dan pembelajaran konvensional pada pembelajaran turunan fungsi ditinjau dari aspek prestasi belajar matematika, kemampuan penyelesaian masalah matematis, kemampuan koneksi matematis, dan Self efficacy siswa SMA Negeri 4 Magelang. Penelitian ini adalah penelitian quasi experiment. Teknik pengumpulan data yang digunakan adalah teknik tes dan nontes. Teknik analisis data yang digunakan adalah uji one sample t-test, uji T2 Hotelling’s, dan uji t-Bonferroni. Hasil penelitian menunjukkan bahwa: (1 strategi pembelajaran REACT efektif pada pembelajaran turunan fungsi ditinjau dari prestasi belajar matematika, kemampuan penyelesaian masalah matematis, kemampuan koneksi matematis, dan Self efficacy siswa SMA Negeri 4 Magelang, dan (2 strategi pembelajaran REACT lebih efektif daripada pembelajaran konvensional pada pembelajaran turunan fungsi ditinjau dari aspek prestasi belajar matematika, kemampuan penyelesaian masalah matematis, kemampuan koneksi matematis, dan Self efficacy siswa SMA Negeri 4 Magelang. Kata Kunci: strategi REACT, prestasi belajar, kemampuan penyelesaian masalah matematis, kemampuan koneksi matematis, dan Self efficacy siswa SMA   THE EFFECTIVENESS OF REACT STRATEGY VIEWED FROM LEARNING ACHIEVEMENT, PROBLEM SOLVING ABILITY, MATHEMATICAL CONNECTION, SELF EFFICACY Abstract The aims of this study are to: (1 to describe the effectiveness of the REACT strategy viewed from Mathematics Learning Achievement, Mathematics Problem Solving Ability, Mathematics Connection Ability, and Student Self efficacy of State Senior High School 4 Magelang Students, and (2 determine a more effective

THE EARNINGS PER SHARE AND INVENTORY TURNOVER RATIOS IN THE GLOBAL FINANCIAL CRISIS: A COMPARATIVE STUDY FOR FOOD AND TEXTILE SECTORS IN ISTANBUL STOCK EXCHANGE

Directory of Open Access Journals (Sweden)

Sudi APAK

2009-01-01

Full Text Available The ongoing financial crisis in the global markets, which originated in the US subprime mortgage segment (real estate and quickly spread into other market segments and countries, is already seen today as one of the biggest financial crises in history. Underlying the subprime crisis had essentially two interrelated factors; the boom in US real estate markets, and the high liquidity demand in the global financial markets. The later period was, in turn, fuelled by the significant easing of US monetary policy over an extended period of time and by the additional boost to global liquidity as many emerging markets had tied their exchange rates to the US dollar and therefore had to match the expansive US monetary policy. The occurrence of market crash or financial crisis is possible key factor of earning per share (EPS and inventory turnover ratios (ITR inefficiency. This paper empirically investigates that the effects of the current financial crisis on the efficiency -earning per share (EPS and inventory turnover ratios- listed food and textile companies in Istanbul Stock Exchange (ISE. The EPS and inventory turnover ratios, applying the multivariate test statistics for the two sub-periods of pre-crisis and the crisis time. The article proceeds in the following manner. Firstly, the study will explain main reasons of global financial crises. Secondly the study will analyze all EPS and inventory turnover ratios changing are of related companies. Finally, that will be argued for adjustment of related ratios of sectors.

Process to separate alkali metal salts from alkali metal reacted hydrocarbons

Energy Technology Data Exchange (ETDEWEB)

Gordon, John Howard; Alvare, Javier; Larsen, Dennis; Killpack, Jeff

2017-06-27

A process to facilitate gravimetric separation of alkali metal salts, such as alkali metal sulfides and polysulfides, from alkali metal reacted hydrocarbons. The disclosed process is part of a method of upgrading a hydrocarbon feedstock by removing heteroatoms and/or one or more heavy metals from the hydrocarbon feedstock composition. This method reacts the oil feedstock with an alkali metal and an upgradant hydrocarbon. The alkali metal reacts with a portion of the heteroatoms and/or one or more heavy metals to form an inorganic phase containing alkali metal salts and reduced heavy metals, and an upgraded hydrocarbon feedstock. The inorganic phase may be gravimetrically separated from the upgraded hydrocarbon feedstock after mixing at a temperature between about 350.degree. C. to 400.degree. C. for a time period between about 15 minutes and 2 hours.

Vaccines, our shared responsibility.

Science.gov (United States)

Pagliusi, Sonia; Jain, Rishabh; Suri, Rajinder Kumar

2015-05-05

The Developing Countries Vaccine Manufacturers' Network (DCVMN) held its fifteenth annual meeting from October 27-29, 2014, New Delhi, India. The DCVMN, together with the co-organizing institution Panacea Biotec, welcomed over 240 delegates representing high-profile governmental and nongovernmental global health organizations from 36 countries. Over the three-day meeting, attendees exchanged information about their efforts to achieve their shared goal of preventing death and disability from known and emerging infectious diseases. Special praise was extended to all stakeholders involved in the success of polio eradication in South East Asia and highlighted challenges in vaccine supply for measles-rubella immunization over the coming decades. Innovative vaccines and vaccine delivery technologies indicated creative solutions for achieving global immunization goals. Discussions were focused on three major themes including regulatory challenges for developing countries that may be overcome with better communication; global collaborations and partnerships for leveraging investments and enable uninterrupted supply of affordable and suitable vaccines; and leading innovation in vaccines difficult to develop, such as dengue, Chikungunya, typhoid-conjugated and EV71, and needle-free technologies that may speed up vaccine delivery. Moving further into the Decade of Vaccines, participants renewed their commitment to shared responsibility toward a world free of vaccine-preventable diseases. Copyright © 2015 The Authors. Published by Elsevier Ltd.. All rights reserved.

ABB and the global market

International Nuclear Information System (INIS)

Lindahl, G.

1994-01-01

Competing in a global environment implies that the authors previous business environment has been less than global, and there are indeed changes underway that lead to a more universal environment. But, there are still differences between regions and especially between the mature economies in the OECD countries and the rapidly developing countries, of which a majority are in Asia. For the OECD countries, the time after World War 2 and up to about 1970 was a period of unprecedented growth. Rebuilding after the war and a general growth of the use of electric power required high investments in power systems and caused a booming market for equipment suppliers. After a trend break in the beginning of the 1970s to less than 40 GW 10 years later, then slowly increased to about 50 GW today. At the same time, annual capacity growth in developing countries increased from less than 20 GW to about 50 GW, i.e. the same level as in OECD. This means that ABB is now passing a cross-over point: from now on less than half of their global market is in their well-known OECD world. And this share will continue to shrink. ABB is now restructuring to fulfill market needs in less developed, developing, and newly industrialized countries. This is the most important change in their global environment is addressed in this article

Numerical simulation of reacting and non-reacting flow in a combustion chamber; Numerisk simulering av reagerande och icke-reagerande stroemning i en braennkammare

Energy Technology Data Exchange (ETDEWEB)

Borg, A.; Revstedt, J.

1996-04-01

The purpose of this work has been to do a preliminary study of how well numerical calculations with different turbulence models can predict the flow and temperature fields of a strongly swirling and combusting flow in an experimental combustion chamber and to see which parameters in the mathematical model are the most important. The combustion chamber on which we have done the calculations is called Validation Rig II and was designed by Volvo Aero Corporation. The main part of the study has been carried out on a non-reacting flow but some work has also been done on reacting flow. In most cases it has not been meaningful to compare the calculations with the measurements because they differ quite a lot from each other. For the non-reacting case the following investigations have been made: * How the solution differs for different turbulence models, * The solutions sensitivity to inlet boundary conditions, * How different types of leakage disturb the flow, and * The difference in results between two different CFD-codes, the commercial code CFDS-Flow3D and a code developed at the department of fluid mechanics. For the reacting cases we have studied the influence of: * one or two reaction steps, * the effects of a change in reaction rate, * the influence of thermal radiation, and * the effects of changing the boundary conditions for temperature on the walls. The results from these calculations show that the inlet turbulence intensity has very little effect on the values of the turbulent quantities as well as the velocity profiles at the outlet. Changing the turbulence model or the outlet boundary conditions gives some change in velocity profiles at the outlet but only marginal effects on the swirl number. 21 refs, 54 figs, 19 tabs

Shared breastfeeding in central Africa

NARCIS (Netherlands)

Ramharter, Michael; Chai, Sanders K.; Adegnika, Ayola A.; Klöpfer, Anna; Längin, Matthias; Agnandji, Selidji T.; Oyakhirome, Sunny; Schwarz, Norbert G.; Grobusch, Martin P.; Issifou, Saadon; Kremsner, Peter G.

2004-01-01

In this study, shared breastfeeding is described asa novel risk factor for vertical HIV transmission. This cross-sectional survey conducted in the central African country Gabon found that 40% of lactating mothers also breastfed other children than their own, and as many children were additionally

Global health research needs global networking

NARCIS (Netherlands)

Ignaciuk, A.; Leemans, R.

2012-01-01

To meet the challenges arising from global environmental change on human health, co-developing common approaches and new alliances of science and society are necessary. The first steps towards defining cross-cutting, health-environment issues were developed by the Global Environmental Change and

DNA fingerprinting approaches to trace Escherichia coli sharing between dogs and owners.

Science.gov (United States)

Naziri, Z; Derakhshandeh, A; Firouzi, R; Motamedifar, M; Shojaee Tabrizi, A

2016-02-01

To determine the prevalence of cross-species sharing of Escherichia coli between healthy dogs and humans living in the same household. Two faecal E. coli isolates from 25 healthy dog-owner pairs and 16 healthy control humans were tested using three fingerprinting methods. The prevalence of within-household sharing of E. coli was 4, 8 and 8% using pulsed-field gel electrophoresis, randomly amplified polymorphic DNA and enterobacterial repetitive intergenic consensus-PCR analyses respectively. Within-household bacterial sharing was more prevalent than across-household sharing (P fingerprinting techniques will help to find ways for reducing the economic impact of E. coli infections. This study support claims that public health concerns regarding the cross-species sharing of E. coli are warranted but this risk is minimal. © 2015 The Society for Applied Microbiology.

Team-based global organizations

DEFF Research Database (Denmark)

Zander, Lena; Butler, Christina; Mockaitis, Audra

2015-01-01

diversity in enhancing team creativity and performance, and 2) the sharing of knowledge in team-based organizations, while the other two themes address global team leadership: 3) the unprecedented significance of social capital for the success of global team leader roles; and 4) the link between shared......This chapter draws on a panel discussion of the future of global organizing as a team-based organization at EIBA 2014 in Uppsala, Sweden. We began by discussing contemporary developments of hybrid forms of hierarchy and teams-based organizing, but we venture to propose that as organizations become...... characterized by decreased importance of hierarchal structures, more fluidity across borders, even a possible dissolution of firm boundaries, we move towards team-based organizing as an alternative to more traditional forms of hierarchical-based organizing in global firms. To provide input for a discussion...

A suite of global, cross-scale topographic variables for environmental and biodiversity modeling

Science.gov (United States)

Amatulli, Giuseppe; Domisch, Sami; Tuanmu, Mao-Ning; Parmentier, Benoit; Ranipeta, Ajay; Malczyk, Jeremy; Jetz, Walter

2018-03-01

Topographic variation underpins a myriad of patterns and processes in hydrology, climatology, geography and ecology and is key to understanding the variation of life on the planet. A fully standardized and global multivariate product of different terrain features has the potential to support many large-scale research applications, however to date, such datasets are unavailable. Here we used the digital elevation model products of global 250 m GMTED2010 and near-global 90 m SRTM4.1dev to derive a suite of topographic variables: elevation, slope, aspect, eastness, northness, roughness, terrain roughness index, topographic position index, vector ruggedness measure, profile/tangential curvature, first/second order partial derivative, and 10 geomorphological landform classes. We aggregated each variable to 1, 5, 10, 50 and 100 km spatial grains using several aggregation approaches. While a cross-correlation underlines the high similarity of many variables, a more detailed view in four mountain regions reveals local differences, as well as scale variations in the aggregated variables at different spatial grains. All newly-developed variables are available for download at Data Citation 1 and for download and visualization at http://www.earthenv.org/topography.

Data Resource Profile: Cross-national and cross-study sociodemographic and health-related harmonized domains from SAGE plus ELSA, HRS and SHARE (SAGE+, Wave 1).

Science.gov (United States)

Minicuci, Nadia; Naidoo, Nirmala; Chatterji, Somnath; Kowal, Paul

2016-10-01

Four longitudinal studies were included in this rigorous harmonization process: the Study on global AGEing and adult health (SAGE); English Longitudinal Study on Ageing (ELSA); US Health and Retirement Study (HRS); and Survey of Health, Ageing and Retirement in Europe (SHARE). An ex-post harmonized process was applied to nine health-related thematic domains (socio-demographic and economic, health states, overall self-report of health and mental state, health examinations, physical and mental performance tests, risk factors, chronic conditions, social network and subjective well-being) for data from the 2004 wave of each study. Large samples of adults aged 50 years and older were available from each study: SAGE, n = 18 886; ELSA, n = 9181; HRS, n = 19 303; and SHARE, n = 29 917. The microdata, along with further details about the harmonization process and all metadata, are available through the World Health Organization (WHO) data archive at [http://apps.who.int/healthinfo/systems/surveydata/index.php/catalog]. Further information and enquiries can be made to [sagesurvey@who.int] or the corresponding author. The data resource will continue to be updated with data across additional waves of these surveys and new waves. © The Author 2016; all rights reserved. Published by Oxford University Press on behalf of the International Epidemiological Association.

Comparison of improved finite-difference WENO schemes for the implicit large eddy simulation of turbulent non-reacting and reacting high-speed shear flows

International Nuclear Information System (INIS)

Zhao, S.; Lardjane, N.; Fedioun, I.

2014-01-01

Improved WENO schemes, Z, M, and their combination MZ, originally designed to capture sharper discontinuities than the classical fifth order Jiang-Shu scheme does, are evaluated for the purpose of implicit large eddy simulation of free shear flows. 1D Fourier analysis of errors reveals the built-in filter and dissipative properties of the schemes, which are subsequently applied to the canonical Rayleigh-Taylor and Taylor-Green flows. Large eddy simulations of a transonic non-reacting and a supersonic reacting air/H2 jets are then performed at resolution 128 * 128 * 512, showing no significant difference in the flow statistics. However, the computational time varies from one scheme to the other, the Z scheme providing the smaller wall-time due to larger allowed time steps. (authors)

Risk Sharing Partnerships With Suppliers: The Case of EMBRAER

Directory of Open Access Journals (Sweden)

Paulo Figueiredo

2008-04-01

Full Text Available Since the mid 1990s, the global aircraft industry has been creating new solutions for product development. Risk-sharing partnerships with suppliers began to be established in an attempt to reduce investments and, consequentially, the dependence on loans. The partners began not only to invest in tooling, engineering and infrastructure, but also to participate more directly in the projects, in the investments and design activities, acquiring rights to future sales income of products. This contractual modality, called risk-sharing partnership, is the focus of this study. Specifically, it analyzes the risk-sharing partnerships made by Embraer during the projects of the ERJ-170/190 family of aircrafts. It also aims to justify these partnerships, considering the current global aircraft market conditions, evaluating the critical success factors, requirements and macro-economic conditions which supported the adoption of this new policy.

Computation of turbulent reacting flow in a solid-propellant ducted rocket

Science.gov (United States)

Chao, Yei-Chin; Chou, Wen-Fuh; Liu, Sheng-Shyang

1995-05-01

A mathematical model for computation of turbulent reacting flows is developed under general curvilinear coordinate systems. An adaptive, streamline grid system is generated to deal with the complex flow structures in a multiple-inlet solid-propellant ducted rocket (SDR) combustor. General tensor representations of the k-epsilon and algebraic stress (ASM) turbulence models are derived in terms of contravariant velocity components, and modification caused by the effects of compressible turbulence is also included in the modeling. The clipped Gaussian probability density function is incorporated in the combustion model to account for fluctuations of properties. Validation of the above modeling is first examined by studying mixing and reacting characteristics in a confined coaxial-jet problem. This is followed by study of nonreacting and reacting SDR combustor flows. The results show that Gibson and Launder's ASM incorporated with Sarkar's modification for compressible turbulence effects based on the general curvilinear coordinate systems yields the most satisfactory prediction for this complicated SDR flowfield.

Nb3Sn dipole magnet reacted after winding

International Nuclear Information System (INIS)

Taylor, C.; Scanlan, R.; Peters, C.; Wolgast, R.; Gilbert, W.; Hassenzahl, W.; Meuser, R.; Rechen, J.

1984-09-01

A 5 cm bore dia., 1-m-long dipole model magnet was constructed by winding un-reacted cable, followed by reaction and epoxy-impregnation. Experience and test results are described on the 1.7 mm dia. internal-tin wire, the eleven-strand flattened cable, fiberglass insulation, and construction of the magnet. Each half of the magnet has two double-pancake-type windings that were reacted in a single operation. The two double-pancakes were then separately vacuum impregnated after soldering the flexible Nb-Ti leads to the Nb 3 Sn conductors. No iron flux return yoke was used. In initial tests a central field of 8.0 T was reached at 4.4 K. However, evidence from training behavior, and 1.8 K tests indicate that premature quenching, rather than critical current of the cable, limited the field intensity. The magnet was reassembled and more rigidly clamped; additional test results are reported

The global landscape of cross-border reproductive care: twenty key findings for the new millennium.

Science.gov (United States)

Inhorn, Marcia C; Patrizio, Pasquale

2012-06-01

Cross-border reproductive care (CBRC), also known as procreative tourism, fertility tourism, or reproductive tourism, is an increasing global phenomenon. This article reviews the expanding scholarly literature on CBRC, with 2010-2011 representing watershed years for CBRC scholarship and activism. Terminological debates, missing data, and lack of international monitoring plague the study of CBRC. Nonetheless, it is widely acknowledged that CBRC is a growing industry, with new global hubs, new intermediaries, new media, and new spaces of interaction. Religious bans and legal restrictions have created a patchwork of 'restrictive' and 'permissive' countries, with law evasion being a primary driver of CBRC. Yet, patient motivations for CBRC are diverse and patients' levels of satisfaction with CBRC and its outcomes are generally high. Thus, scholarly concern with CBRC as law evasion must be tempered with qualitative studies of positive patient experiences. CBRC can be considered a form of 'global gynecology' in which reproductive medicine, tourism, and commerce are converging in the second decade of the new millennium.

Knowledge Sharing in Knowledge-Intensive Firms

DEFF Research Database (Denmark)

Gupta, Akshey; Michailova, Snejina

2004-01-01

This paper is a study of the knowledge-sharing difficulties experienced by three departments in a knowledge-intensive firm. The case organization is a global consulting firm that has been on the forefront of knowledge management and has won several knowledge management related international accla...

REAC/TS radiation accident registry. Update of accidents in the United States

International Nuclear Information System (INIS)

Ricks, R.C.; Berger, M.E.; Holloway, E.C.; Goans, R.E.

2000-01-01

Serious injury due to ionizing radiation is a rare occurrence. From 1944 to the present, 243 US accidents meeting dose criteria for classification as serious are documented in the REAC/TS Registry. Thirty individuals have lost their lives in radiation accidents in the United States. The Registry is part of the overall REAC/TS program providing 24-hour direct or consultative assistance regarding medical and heath physics problems associated with radiation accidents in local, national, and international incidents. The REAC/TS Registry serves as a repository of medically important information documenting the consequences of these accidents. Registry data are gathered from various sources. These include reports from the World Heath Organization (WHO), International Atomic Energy Agency (IAEA), US Nuclear Regulatory Commission (US NRC), state radiological health departments, medical/health physics literature, personal communication, the Internet, and most frequently, from calls for medical assistance to REAC/TS, as part of our 24-hour medical assistance program. The REAC/TS Registry for documentation of radiation accidents serves several useful purposes: 1) weaknesses in design, safety practices, training or control can be identified, and trends noted; 2) information regarding the medical consequences of injuries and the efficacy of treatment protocols is available to the treating physician; and 3) Registry case studies serve as valuable teaching tools. This presentation will review and summarize data on the US radiation accidents including their classification by device, accident circumstances, and frequency by respective states. Data regarding accidents with fatal outcomes will be reviewed. The inclusion of Registry data in the IAEA's International Reporting System of Radiation Events (RADEV) will also be discussed. (author)

78 FR 15680 - Information Sharing With Agency Stakeholders: Public Meeting

Science.gov (United States)

2013-03-12

...] Information Sharing With Agency Stakeholders: Public Meeting AGENCY: Animal and Plant Health Inspection... stakeholders regarding cross-Agency strategic priorities. We are also announcing that APHIS is hosting a public... opportunity for stakeholders to ask questions and share their perspective. DATES: The meeting will be held on...

Human autoantibodies against Clq: lack of cross reactivity with the collectins mannan-binding protein, lung surfactant protein A and bovine conglutinin.

Science.gov (United States)

Mårtensson, U; Thiel, S; Jensenius, J C; Sjöholm, A G

1996-03-01

The collectins, a group of humoral C-type lectins, have globular and collagen-like regions and share structural features with the complement protein C1q. The question was asked if autoantibodies to the collagen-like region of C1q (anti-C1qCLR) might cross-react with collectins, such as mannan-binding protein (MBP), lung surfactant protein A (SP-A) and bovine conglutinin (BK). Anti-C1qCLR antibodies of the systemic lupus erythematosus (SLE) type and anti-C1qCLR antibodies of the hypocomplementemic urticarial vasculitis syndrome (HUVS) type were investigated. Cross-absorption and elution experiments combined with antibody detection by enzyme-linked immunosorbent assay (ELISA) and immunoblot analysis gave no evidence of cross-reactive anti-C1qCLR antibodies. However, one serum with HUVS type anti-C1qCLR antibodies contained anti-MBP antibodies that were cross-reactive with SP-A. Judging from results of ELISA inhibition experiments and immunoblot analysis, four SLE sera contained antibodies to native BK, while two sera with HUVS type anti-C1qCLR antibodies contained antibodies to epitopes of denatured BK. This might imply that autoimmunity to collagen-like structures is not restricted to C1qCLR in HUVS and HUVS/SLE overlap syndromes.

Cross-reactive Legionella antigens and the antibody response during infection

DEFF Research Database (Denmark)

Bangsborg, Jette Marie; Shand, G; Pearlman, E

1991-01-01

In order to define cross-reactive Legionella antigens suitable for diagnostic purposes, we investigated sonicate antigens from two Legionella species, including two serogroups of L. pneumophila. The antigens were reacted with heterologous and homologous rabbit antisera in Western blot. Sera from ...

Studies on the different forms of material reacting with antiinsulin antibodies in the fetal and adult rat

International Nuclear Information System (INIS)

Felix, J.M.; Sutter-Dub, M.T.; Legrele, C.; Reims Univ., 51

1975-01-01

The nature of peak B (MW = 10-12,000, proinsulin) and peak C (MW = 50-100,000, 'big big' insulin) materials detected by the double antibody (DA) procedure in elution profiles of rat sera after Sephadex G 50 or G 100 chromatography (cf. preceding companion paper) is further investigated. Peak B is converted by mild tryptic digestion in an immunoreactive material behaving in rechromatography exactly like insulin monomer. Peak C is less easily detected by the dextran coated charcoal (DCC) method; it resists 8 M urea 37 0 C for 1 hr, is not an artifact due to the complement system; its relative importance is very much reduced in pancreatic extracts or perifusates. Incubation of biologically active 125 I labelled insulin in rat sera results in appearance of labelled material behaving on chromatography like peak C natural material, having the electrophoretic mobility of rat α 1 globulins and albumin, and resisting 8 M urea, acidic pHs and 0.5 M NaCl. Similar incubation in buffer supplemented with bovine albumin results in appearance of a labelled material having the electrophoretic mobility of beef albumin; N-ethyl-maleimide provides against this binding, which might result from (S-S)-(SH) interchanges. Rat α globulins and albumin (but not beef albumin) cross-react with the DA procedure; they do not react with the DCC method. Insulin bound to plasma proteins react with both methods. It is suggested that peak C material, as detected by the DA method in rat serum, consists both of insulin covalently bound to plasma proteins and of certain plasma proteins; the DCC method detects only bound insulin. In streptozotocin treated rats, peak C material persists after the complete disappearance of insulin and proinsulin when detected by the (DA) procedure, but disappears when detected by the DCC procedure. (orig.) [de

Studies on the different forms of material reacting with antiinsulin antibodies in the fetal and adult rat

Energy Technology Data Exchange (ETDEWEB)

Felix, J M; Sutter-Dub, M T; Legrele, C [Reims Univ., 51 (France). Lab. de Physiologie Animale; Reims Univ., 51 (France). Centre de Biologie et de Biochimie du Developpement)

1975-09-01

The nature of peak B (MW = 10-12,000, proinsulin) and peak C (MW = 50-100,000, 'big big' insulin) materials detected by the double antibody (DA) procedure in elution profiles of rat sera after Sephadex G 50 or G 100 chromatography (cf. preceding companion paper) is further investigated. Peak B is converted by mild tryptic digestion in an immunoreactive material behaving in rechromatography exactly like insulin monomer. Peak C is less easily detected by the dextran coated charcoal (DCC) method; it resists 8 M urea 37/sup 0/C for 1 hr, is not an artifact due to the complement system; its relative importance is very much reduced in pancreatic extracts or perifusates. Incubation of biologically active /sup 125/I labelled insulin in rat sera results in appearance of labelled material behaving on chromatography like peak C natural material, having the electrophoretic mobility of rat ..cap alpha../sub 1/ globulins and albumin, and resisting 8 M urea, acidic pHs and 0.5 M NaCl. Similar incubation in buffer supplemented with bovine albumin results in appearance of a labelled material having the electrophoretic mobility of beef albumin; N-ethyl-maleimide provides against this binding, which might result from (S-S)-(SH) interchanges. Rat ..cap alpha.. globulins and albumin (but not beef albumin) cross-react with the DA procedure; they do not react with the DCC method. Insulin bound to plasma proteins react with both methods. It is suggested that peak C material, as detected by the DA method in rat serum, consists both of insulin covalently bound to plasma proteins and of certain plasma proteins; the DCC method detects only bound insulin. In streptozotocin treated rats, peak C material persists after the complete disappearance of insulin and proinsulin when detected by the (DA) procedure, but disappears when detected by the DCC procedure.

Supporting the development of shared understanding in distributed design teams

OpenAIRE

Cash, Philip; Dekoninck, Elies; Ahmed-Kristensen, Saeema

2017-01-01

Distributed teams are an increasingly common feature of engineering design work. One key factor in the success of these teams is the development of short- and longer-term shared understanding. A lack of shared understanding has been recognized as a significant challenge, particularly in the context of globally distributed engineering activities. A major antecedent for shared understanding is question asking and feedback. Building on question-asking theory this work uses a quasi-experimental s...

General protein-protein cross-linking.

Science.gov (United States)

Alegria-Schaffer, Alice

2014-01-01

This protocol describes a general protein-to-protein cross-linking procedure using the water-soluble amine-reactive homobifunctional BS(3) (bis[sulfosuccinimidyl] suberate); however, the protocol can be easily adapted using other cross-linkers of similar properties. BS(3) is composed of two sulfo-NHS ester groups and an 11.4 Å linker. Sulfo-NHS ester groups react with primary amines in slightly alkaline conditions (pH 7.2-8.5) and yield stable amide bonds. The reaction releases N-hydroxysuccinimide (see an application of NHS esters on Labeling a protein with fluorophores using NHS ester derivitization). © 2014 Elsevier Inc. All rights reserved.

A stochastic model of particle dispersion in turbulent reacting gaseous environments

Science.gov (United States)

Sun, Guangyuan; Lignell, David; Hewson, John

2012-11-01

We are performing fundamental studies of dispersive transport and time-temperature histories of Lagrangian particles in turbulent reacting flows. The particle-flow statistics including the full particle temperature PDF are of interest. A challenge in modeling particle motions is the accurate prediction of fine-scale aerosol-fluid interactions. A computationally affordable stochastic modeling approach, one-dimensional turbulence (ODT), is a proven method that captures the full range of length and time scales, and provides detailed statistics of fine-scale turbulent-particle mixing and transport. Limited results of particle transport in ODT have been reported in non-reacting flow. Here, we extend ODT to particle transport in reacting flow. The results of particle transport in three flow configurations are presented: channel flow, homogeneous isotropic turbulence, and jet flames. We investigate the functional dependence of the statistics of particle-flow interactions including (1) parametric study with varying temperatures, Reynolds numbers, and particle Stokes numbers; (2) particle temperature histories and PDFs; (3) time scale and the sensitivity of initial and boundary conditions. Flow statistics are compared to both experimental measurements and DNS data.

Why is the wage share falling in emerging economies? Industry level evidence

OpenAIRE

Guschanski, Alexander; Onaran, Özlem

2017-01-01

This article presents an econometric analysis of the wage share in seven emerging economies. We focus on the effect of globalisation, captured by participation in global value chains and financial integration, indicators of bargaining power of labour and technological change on the wage share. We use input-output tables that allow us to obtain detailed measures of global value chain participation, and sectoral data to distinguish the effect on high- and low-skilled workers and within manufact...

Keefektifan Strategi Pembelajaran React Pada Kemampuan Siswa Kelas VII Aspek Komunikasi Matematis

Directory of Open Access Journals (Sweden)

A.T. Arifin

2014-06-01

Full Text Available AbstrakTujuan penelitian ini adalah mengetahui pembelajaran dengan strategi REACT efektif ter-hadap kemampuan komunikasi matematis siswa. Metode pengumpulan data dilakukan de-ngan metode dokumentasi, tes, dan observasi. Hasil uji proporsi menunjukkan bahwa hasil belajar siswa kelas eksperimen pada aspek kemampuan komunikasi matematis telah men-capai ketuntasan klasikal, mencapai lebih dari 80 % yaitu sebesar 96,7%. Dilihat dari nilai rata-rata tes kemampuan komunikasi matematis kelas eksperimen  adalah 83,61 sedangkan kelas kontrol adalah 73,79 dapat disimpulkan bahwa kemampuan komunikasi matematis siswa kelas eksperimen lebih baik daripada kemampuan komunikasi matematis siswa kon-trol. Hasil penelitian menunjukkan bahwa penerapan strategi pembelajaran REACT efektif terhadap kemampuan komunikasi matematis siswa materi segiempat kelas VII SMP Negeri 1 Gembong. Kata kunci:      keefektifan, kemampuan komunikasi matematis, Relating Experiencing Applying Cooperating Transferring (REACT  AbstractThe purpose of this study was to determine the effectiveness of the application of REACT learning strategy approach to mathematic communication ability of students. Methods of data collection is done by the method of documentation, testing, and observation. The test results showed that the proportion of student learning outcomes in the experimental class with the aspects of mathematic communication ability has reached the classical completeness, reached more than 80% is equal to 96.7%. Judging from the value of the average test learners' ability to mathematic communication experimental class was 83.61 while the control class is 73.79 it can be concluded that the mathematic communication skills of learners experimental classes are better than mathematic communication abilities of learners control class. The results showed that the application of REACT learning strategy approach effective to mathematic communication abilities of students of class VII

A model for cross-cultural reciprocal interactions through mass media.

Science.gov (United States)

González-Avella, Juan Carlos; Cosenza, Mario G; San Miguel, Maxi

2012-01-01

We investigate the problem of cross-cultural interactions through mass media in a model where two populations of social agents, each with its own internal dynamics, get information about each other through reciprocal global interactions. As the agent dynamics, we employ Axelrod's model for social influence. The global interaction fields correspond to the statistical mode of the states of the agents and represent mass media messages on the cultural trend originating in each population. Several phases are found in the collective behavior of either population depending on parameter values: two homogeneous phases, one having the state of the global field acting on that population, and the other consisting of a state different from that reached by the applied global field; and a disordered phase. In addition, the system displays nontrivial effects: (i) the emergence of a largest minority group of appreciable size sharing a state different from that of the applied global field; (ii) the appearance of localized ordered states for some values of parameters when the entire system is observed, consisting of one population in a homogeneous state and the other in a disordered state. This last situation can be considered as a social analogue to a chimera state arising in globally coupled populations of oscillators.

Research on the Mechanism of Cross Organizational Knowledge Sharing in BIM Competitive Environment

Directory of Open Access Journals (Sweden)

Zhong Wei

2017-01-01

Full Text Available Co-opetition under the environment of BIM implementation process because the level is not high resulting in the project BIM application value of incomplete knowledge sharing among organizations, thus establishing good knowledge can effectively solve this problem and achieve the overall benefit and benefit sharing mechanism in the project organization. This paper defines five competing modes according to the competing degree of organization between different BIM applications, including imperfect competition, competition, competition and cooperation, full cooperation and cooperation, and put forward the conceptual model and related assumptions. Analysis of the effect of path and effect of project determined in BIM application mode, the concurrence of knowledge sharing, efficiency and overall efficiency of the project within the organization through the survey and empirical results, and according to the proposed contract, the distribution of benefits and work three kinds of knowledge sharing mechanism implementation path.

Marketing and Globalization of the Brewing Industry

DEFF Research Database (Denmark)

Madsen, Erik Strøjer; Wu, Yanqing

2016-01-01

The globalization of the brewing industry after the turn of the century through a large wave of mergers and acquisitions has changed the structure of the world beer markets. The chapter tracks the development in industry concentrations from 2002 to 2012 and points to high transportation costs...... for beers and economies of scale at the firm level in advertising and sales efforts as the main factors behind the wave of cross-country mergers and acquisitions. Using firm-level data from the largest breweries, the estimations verify significant economies of scale at the firm level in marketing...... significant economies of scale benefits at the firm level to be shared between the merging partners as marketing and distribution costs are very high in this industry....

Sharing tools and best practice in Global Sensitivity Analysis within academia and with industry

Science.gov (United States)

Wagener, T.; Pianosi, F.; Noacco, V.; Sarrazin, F.

2017-12-01

We have spent years trying to improve the use of global sensitivity analysis (GSA) in earth and environmental modelling. Our efforts included (1) the development of tools that provide easy access to widely used GSA methods, (2) the definition of workflows so that best practice is shared in an accessible way, and (3) the development of algorithms to close gaps in available GSA methods (such as moment independent strategies) and to make GSA applications more robust (such as convergence criteria). These elements have been combined in our GSA Toolbox, called SAFE (www.safetoolbox.info), which has up to now been adopted by over 1000 (largely) academic users worldwide. However, despite growing uptake in academic circles and across a wide range of application areas, transfer to industry applications has been difficult. Initial market research regarding opportunities and barriers for uptake revealed a large potential market, but also highlighted a significant lack of knowledge regarding state-of-the-art methods and their potential value for end-users. We will present examples and discuss our experience so far in trying to overcome these problems and move beyond academia in distributing GSA tools and expertise.

Building collaboration through shared actions: The experience of the Global Network for Disaster Reduction

Directory of Open Access Journals (Sweden)

Terry Gibson

2012-10-01

Full Text Available This article asks how the emergent Global Network for Disaster Reduction has built collaboration and impact. Observation of the network’s journey nuanced the researcher’s initial hypothesis in marked ways. A ‘reflective practitioner’ perspective is adopted, locating action within two relevant theoretical frameworks to aid understanding and define future progress. Development showed an early emphasis on a ‘community of practice’ model. However, this appeared ineffective in creating the intended collaboration and led to the recognition of the power of shared action. This observation is framed within the thinking of Freire (1996 on action and reflection as a means of empowerment. The political dimension of the network’s activity is recognised, and is related to Gaventa’s (1980 thinking on the creation of political space. The article attempts to show that combining cycles of action and reflection in the network’s activity (i.e. creating a practitioner focus with a wider investigation of relevant literature and thinking can be helpful in framing understanding and determining future strategy. It concludes by suggesting that a proposed framework of ‘communities of praxis’ may have a broader application in the development of networks.

Simultaneous Temperature and Velocity Diagnostic for Reacting Flows, Phase I

Data.gov (United States)

National Aeronautics and Space Administration — A diagnostic technique is proposed for measuring temperature and velocity simultaneously in a high temperature reacting flow for aiding research in propulsion. The...

Ultrasensitive immunoradiometric assay for chorionic gonadotropin which does not cross-react with luteinizing hormone nor free β chain of hCG and which detects hCG in blood of non-pregnant humans

International Nuclear Information System (INIS)

Griffin, J.; Odell, W.D.

1987-01-01

A sensitive, non-competitive, two-monoclonal antibody, sandwich-type or immunoradiometric assay has been developed for human chorionic gonadotropin (hCG) which shows no cross-reaction with the free β chain of hCG nor with human luteinizing hormone (LH). In the assay procedure, two, highly selected monoclonal antibodies reacted in solution with hCG to be quantified. One antibody was covalently conjugated to biotin. This antibody was specific for the β subunit of hCG, and showed no reaction with LH nor the α subunit. The second antibody was labelled with 125 I and was specific for intact hCG and LH, showing no cross-reaction with βhCG nor the α subunit. The separation system was a polystyrene ball conjugated with biotin. This ball bound via an avidin bridge the monoclonal 'sandwich' containing hCG. Counts per minute bound to the ball were directly proportional to the amount of hCG present. The assay was specific for whole hCG and showed no reaction with βhCG, βLH, intact LH nor the free α subunit. Sensitivity was adequate to detect 'hCG-like' material in all post menopausal women and, when single samples were obtained, in over 2/3 of normal men. When multiple samples were obtained, 'hCG-like' material was detectable in all eugonadal adults studied. 27 refs.; 4 figs.; 1 table

Developing Dynamic Single Page Web Applications Using Meteor : Comparing JavaScript Frameworks: Blaze and React

OpenAIRE

Yetayeh, Asabeneh

2017-01-01

This paper studies Meteor which is a JavaScript full-stack framework to develop interactive single page web applications. Meteor allows building web applications entirely in JavaScript. Meteor uses Blaze, React or AngularJS as a view layer and Node.js and MongoDB as a back-end. The main purpose of this study is to compare the performance of Blaze and React. A multi-user Blaze and React web applications with similar HTML and CSS were developed. Both applications were deployed on Heroku’s w...

A model for reaction rates in turbulent reacting flows

Science.gov (United States)

Chinitz, W.; Evans, J. S.

1984-01-01

To account for the turbulent temperature and species-concentration fluctuations, a model is presented on the effects of chemical reaction rates in computer analyses of turbulent reacting flows. The model results in two parameters which multiply the terms in the reaction-rate equations. For these two parameters, graphs are presented as functions of the mean values and intensity of the turbulent fluctuations of the temperature and species concentrations. These graphs will facilitate incorporation of the model into existing computer programs which describe turbulent reacting flows. When the model was used in a two-dimensional parabolic-flow computer code to predict the behavior of an experimental, supersonic hydrogen jet burning in air, some improvement in agreement with the experimental data was obtained in the far field in the region near the jet centerline. Recommendations are included for further improvement of the model and for additional comparisons with experimental data.

Out for blood. The newly overhauled American Red Cross is thirsty for a bigger share of the $2 billion business of supplying blood to hospitals.

Science.gov (United States)

Hensley, S

1998-06-22

The newly overhauled American Red Cross, led by President Elizabeth Dole (left), has launched an ambitious campaign to increase its piece of the more than $2 billion business of supplying blood to hospitals. Its quest for market share has sparked what some call a "blood war" with its main competitors: independent, community-governed blood banks affiliated with America's Blood Centers.

US forest products in the global economy

Science.gov (United States)

Dave N Wear; Jeff Prestemon; Michaela O. Foster

2015-01-01

The United States’ shares of global industrial roundwood production and derivative products have declined precipitously since the 1990s. We evaluate the extent of these declines compared with those of major producing countries from 1961 to 2013. We find that the US global share of industrial roundwood peaked at 28% in 1999 but by 2013 was at 17%, with the decline...

Globalization of Problem-based Learning (PBL: Cross-cultural Implications

Directory of Open Access Journals (Sweden)

Matthew Choon-Eng Gwee

2008-03-01

Full Text Available Problem-based learning (PBL is essentially a learning system design that incorporates several educational strategies to optimize student-centered learning outcomes beyond just knowledge acquisition. PBL was implemented almost four decades ago as an innovative and alternative pathway to learning in medical education in McMaster University Medical School. Since then, PBL has spread widely across the world and has now been adopted globally, including in much of Asia. The globalization of PBL has important cross-cultural implications. Delivery of instruction in PBL involves active peer teaching-learning in an open communication style. Consequently, this may pose an apparent serious conflict with the Asian communication style generally dominated by a cultural reticence. However, evidence available, especially from the PBL experience of some senior Korean medical students doing an elective in the University of Toronto Medical School and the cross-cultural PBL experience initiated by Kaohsiung Medical University, strongly suggests creating a conducive and supportive learning environment for students learning in a PBL setting can overcome the perceived cultural barriers; that is, nurture matters more than culture in the learning environment. Karaoke is very much an Asian initiative. The Karaoke culture and philosophy provide a useful lesson on how to create a conducive and supportive environment to encourage, enhance and motivate group activity. Some key attributes associated with Asian culture are in fact consistent with, and aligned to, some of the basic tenets of PBL, including the congruence between the Asian emphasis on group before individual interest, and the collaborative small group learning design used in PBL. Although there are great expectations of the educational outcomes students can acquire from PBL, the available evidence supports the contention the actual educational outcomes acquired from PBL do not really match the expected

Globalization of problem-based learning (PBL): cross-cultural implications.

Science.gov (United States)

Gwee, Matthew Choon-Eng

2008-03-01

Problem-based learning (PBL) is essentially a learning system design that incorporates several educational strategies to optimize student-centered learning outcomes beyond just knowledge acquisition. PBL was implemented almost four decades ago as an innovative and alternative pathway to learning in medical education in McMaster University Medical School. Since then, PBL has spread widely across the world and has now been adopted globally, including in much of Asia. The globalization of PBL has important cross-cultural implications. Delivery of instruction in PBL involves active peer teaching-learning in an open communication style. Consequently, this may pose an apparent serious conflict with the Asian communication style generally dominated by a cultural reticence. However, evidence available, especially from the PBL experience of some senior Korean medical students doing an elective in the University of Toronto Medical School and the cross-cultural PBL experience initiated by Kaohsiung Medical University, strongly suggests creating a conducive and supportive learning environment for students learning in a PBL setting can overcome the perceived cultural barriers; that is, nurture matters more than culture in the learning environment. Karaoke is very much an Asian initiative. The Karaoke culture and philosophy provide a useful lesson on how to create a conducive and supportive environment to encourage, enhance and motivate group activity. Some key attributes associated with Asian culture are in fact consistent with, and aligned to, some of the basic tenets of PBL, including the congruence between the Asian emphasis on group before individual interest, and the collaborative small group learning design used in PBL. Although there are great expectations of the educational outcomes students can acquire from PBL, the available evidence supports the contention the actual educational outcomes acquired from PBL do not really match the expected educational outcomes commonly

AgMIP 1.5°C Assessment: Mitigation and Adaptation at Coordinated Global and Regional Scales

Science.gov (United States)

Rosenzweig, C.

2016-12-01

The AgMIP 1.5°C Coordinated Global and Regional Integrated Assessments of Climate Change and Food Security (AgMIP 1.5 CGRA) is linking site-based crop and livestock models with similar models run on global grids, and then links these biophysical components with economics models and nutrition metrics at regional and global scales. The AgMIP 1.5 CGRA assessment brings together experts in climate, crop, livestock, economics, nutrition, and food security to define the 1.5°C Protocols and guide the process throughout the assessment. Scenarios are designed to consistently combine elements of intertwined storylines of future society including socioeconomic development (Shared Socioeconomic Pathways), greenhouse gas concentrations (Representative Concentration Pathways), and specific pathways of agricultural sector development (Representative Agricultural Pathways). Shared Climate Policy Assumptions will be extended to provide additional agricultural detail on mitigation and adaptation strategies. The multi-model, multi-disciplinary, multi-scale integrated assessment framework is using scenarios of economic development, adaptation, mitigation, food policy, and food security. These coordinated assessments are grounded in the expertise of AgMIP partners around the world, leading to more consistent results and messages for stakeholders, policymakers, and the scientific community. The early inclusion of nutrition and food security experts has helped to ensure that assessment outputs include important metrics upon which investment and policy decisions may be based. The CGRA builds upon existing AgMIP research groups (e.g., the AgMIP Wheat Team and the AgMIP Global Gridded Crop Modeling Initiative; GGCMI) and regional programs (e.g., AgMIP Regional Teams in Sub-Saharan Africa and South Asia), with new protocols for cross-scale and cross-disciplinary linkages to ensure the propagation of expert judgment and consistent assumptions.

Different event-related patterns of gamma-band power in brain waves of fast- and slow-reacting subjects.

Science.gov (United States)

Jokeit, H; Makeig, S

1994-01-01

Fast- and slow-reacting subjects exhibit different patterns of gamma-band electroencephalogram (EEG) activity when responding as quickly as possible to auditory stimuli. This result appears to confirm long-standing speculations of Wundt that fast- and slow-reacting subjects produce speeded reactions in different ways and demonstrates that analysis of event-related changes in the amplitude of EEG activity recorded from the human scalp can reveal information about event-related brain processes unavailable using event-related potential measures. Time-varying spectral power in a selected (35- to 43-Hz) gamma frequency band was averaged across trials in two experimental conditions: passive listening and speeded reacting to binaural clicks, forming 40-Hz event-related spectral responses. Factor analysis of between-subject event-related spectral response differences split subjects into two near-equal groups composed of faster- and slower-reacting subjects. In faster-reacting subjects, 40-Hz power peaked near 200 ms and 400 ms poststimulus in the react condition, whereas in slower-reacting subjects, 40-Hz power just before stimulus delivery was larger in the react condition. These group differences were preserved in separate averages of relatively long and short reaction-time epochs for each group. gamma-band (20-60 Hz)-filtered event-related potential response averages did not differ between the two groups or conditions. Because of this and because gamma-band power in the auditory event-related potential is small compared with the EEG, the observed event-related spectral response features must represent gamma-band EEG activity reliably induced by, but not phase-locked to, experimental stimuli or events. PMID:8022783

Study of subgrid-scale velocity models for reacting and nonreacting flows

Science.gov (United States)

Langella, I.; Doan, N. A. K.; Swaminathan, N.; Pope, S. B.

2018-05-01

A study is conducted to identify advantages and limitations of existing large-eddy simulation (LES) closures for the subgrid-scale (SGS) kinetic energy using a database of direct numerical simulations (DNS). The analysis is conducted for both reacting and nonreacting flows, different turbulence conditions, and various filter sizes. A model, based on dissipation and diffusion of momentum (LD-D model), is proposed in this paper based on the observed behavior of four existing models. Our model shows the best overall agreements with DNS statistics. Two main investigations are conducted for both reacting and nonreacting flows: (i) an investigation on the robustness of the model constants, showing that commonly used constants lead to a severe underestimation of the SGS kinetic energy and enlightening their dependence on Reynolds number and filter size; and (ii) an investigation on the statistical behavior of the SGS closures, which suggests that the dissipation of momentum is the key parameter to be considered in such closures and that dilatation effect is important and must be captured correctly in reacting flows. Additional properties of SGS kinetic energy modeling are identified and discussed.

Lonergan's philosophy as grounding for cross-disciplinary research.

Science.gov (United States)

Kane, Anne

2014-04-01

Increasingly, nurses conduct scientific inquiry into complex health-care problems by collaborating on teams with researchers from other highly specialized fields. As cross-disciplinary research proliferates and becomes institutionalized globally, researchers will increasingly encounter the need to integrate their particular research perspectives within inquiries without sacrificing the potential contributions of their discipline-specific expertise. The work of the philosopher Bernard Lonergan (1904–1984) offers the necessary philosophical grounding. Here, I defend a role for philosophy in cross-disciplinary research and present selected ideas in Lonergan's work. These include: (1) a dynamic, normative pattern that each inquirer operates uniquely also forms the common core, or unity, in knowing; (2) the possibility of cross-disciplinary knowledge development is dependent on each researcher's consciousness of her or his attentiveness, intelligence, reasonableness, and responsibleness; and (3) shifts in researchers' viewpoints, or horizons, facilitate their collaborative inquiry and their grasp of the unity in knowing. The desire to know, shared by team members, drives their inquiry. Lonergan's stance is consistent with nursing values because it respects, but does not unconditionally privilege, any researcher or discipline. Arguments support a claim that Lonergan's perspective is well suited to guide nurse researchers participating on cross-disciplinary health research teams.

Photodouble ionization differential cross sections for D2 with various electron energy sharing conditions

International Nuclear Information System (INIS)

Seccombe, D.P.; Collins, S.A.; Reddish, T.J.; Selles, P.; Malegat, L.; Huetz, A.; Kazansky, A.K.

2002-01-01

The mutual angular distributions of the two ejected electrons following direct photodouble ionization have been measured for D 2 at an excess energy (E) of 25 eV using linearly polarized light. These (γ, 2e) 'triple' differential cross sections (TDCSs) were obtained for asymmetric electron energy conditions with energy sharing ratios (R=E 2 /E 1 ) of R=24, 11.5, 4 and 2.57. In all cases the 'reference' electron (energy = E 1 ) was oriented along the direction of the electric field vector (ε) and detected in coincidence with a second electron (energy = E 2 ) coplanar with ε and the photon beam direction (kγ). For comparison, helium TDCSs were obtained for the same E and R values under nearly identical spectrometer conditions. These show very good agreement with the results of hyperspherical-R-matrix with semi-classical outgoing waves calculations, thus providing even more confidence in the D 2 TDCSs where there is as yet no accurate ab initio theory. The similarities and differences between the experimental results associated with the two targets are qualitatively discussed in terms of Feagin's model (Feagin J M 1998 J. Phys. B: At. Mol. Opt. Phys. 31 L729). (author)

Nurse manager perspective of staff participation in unit level shared governance.

Science.gov (United States)

Cox Sullivan, Sheila; Norris, Mitzi R; Brown, Lana M; Scott, Karen J

2017-11-01

To examine the nurse manager perspective surrounding implementation of unit level shared governance in one Veterans Health Administration facility. Nursing shared governance is a formal model allowing nursing staff decision-making input into clinical practice, quality improvement, evidence-based practice and staff professional development. Unit level shared governance is a management process where decision authority is delegated to nursing staff at the unit level. Convenience sampling was used to recruit ten nurse managers who participated in face-to-face semi-structured interviews. Data were analysed using content analysis and constant comparison techniques. Demographic data were described using descriptive statistics. The participants included seven female and three male nurse managers with seven Caucasian and three African American. Participant quotes were clustered to identify sub-themes that were then grouped into four global themes to describe unit level shared governance. The global themes were: (1) motivation, (2) demotivation, (3) recommendations for success, and (4) outcomes. These research findings resonate with previous studies that shared governance may be associated with increased nurse empowerment, self-management, engagement, and satisfaction. These findings reflect the need for nurse managers to promote and recognize staff participation in unit level shared governance. © 2017 John Wiley & Sons Ltd.

Effects of Fusion Tack Welds on Self-Reacting Friction Stir Welds

Science.gov (United States)

Nunes, A. C., Jr.; Pendleton, M. L.; Brooke, S. A.; Russell, C. K.

2012-01-01

In order to know whether fusion tack welds would affect the strength of self-reacting friction stir seam welds in 2195-T87 aluminum alloy, the fracture stresses of 144 tensile test coupons cut from 24 welded panels containing segments of friction stir welds were measured. Each of the panels was welded under unique processing conditions. A measure of the effect of the tack welds for each panel was devised. An analysis of the measures of the tack weld effect supported the hypothesis that fusion tack welds do not affect the strength of self-reacting friction stir welds to a 5% level of confidence.

Direct numerical simulations of reacting flows with detailed chemistry using many-core/GPU acceleration

KAUST Repository

Herná ndez Pé rez, Francisco E.; Mukhadiyev, Nurzhan; Xu, Xiao; Sow, Aliou; Lee, Bok Jik; Sankaran, Ramanan; Im, Hong G.

2018-01-01

A new direct numerical simulation (DNS) code for multi-component gaseous reacting flows has been developed at KAUST, with the state-of-the-art programming model for next generation high performance computing platforms. The code, named KAUST Adaptive Reacting Flows Solver (KARFS), employs the MPI+X programming, and relies on Kokkos for “X” for performance portability to multi-core, many-core and GPUs, providing innovative software development while maintaining backward compatibility with established parallel models and legacy code. The capability and potential of KARFS to perform DNS of reacting flows with large, detailed reaction mechanisms is demonstrated with various model problems involving ignition and turbulent flame propagations with varying degrees of chemical complexities.

Direct numerical simulations of reacting flows with detailed chemistry using many-core/GPU acceleration

KAUST Repository

Hernández Pérez, Francisco E.

2018-03-29

A new direct numerical simulation (DNS) code for multi-component gaseous reacting flows has been developed at KAUST, with the state-of-the-art programming model for next generation high performance computing platforms. The code, named KAUST Adaptive Reacting Flows Solver (KARFS), employs the MPI+X programming, and relies on Kokkos for “X” for performance portability to multi-core, many-core and GPUs, providing innovative software development while maintaining backward compatibility with established parallel models and legacy code. The capability and potential of KARFS to perform DNS of reacting flows with large, detailed reaction mechanisms is demonstrated with various model problems involving ignition and turbulent flame propagations with varying degrees of chemical complexities.

Sharing a quota on cumulative carbon emissions

International Nuclear Information System (INIS)

Raupach, Michael R.; Davis, Steven J.; Peters, Glen P.; Andrew, Robbie M.; Canadell, Josep G.; Ciais, Philippe

2014-01-01

Any limit on future global warming is associated with a quota on cumulative global CO 2 emissions. We translate this global carbon quota to regional and national scales, on a spectrum of sharing principles that extends from continuation of the present distribution of emissions to an equal per-capita distribution of cumulative emissions. A blend of these endpoints emerges as the most viable option. For a carbon quota consistent with a 2 C warming limit (relative to pre-industrial levels), the necessary long-term mitigation rates are very challenging (typically over 5% per year), both because of strong limits on future emissions from the global carbon quota and also the likely short-term persistence in emissions growth in many regions. (authors)

Hidden concerns of sharing research data by low/middle-income country scientists.

Science.gov (United States)

Bezuidenhout, Louise; Chakauya, Ereck

2018-01-01

There has considerable interest in bringing low/middle-income countries (LMIC) scientists into discussions on Open Data - both as contributors and users. The establishment of in situ data sharing practices within LMIC research institutions is vital for the development of an Open Data landscape in the Global South. Nonetheless, many LMICs have significant challenges - resource provision, research support and extra-laboratory infrastructures. These low-resourced environments shape data sharing activities, but are rarely examined within Open Data discourse. In particular, little attention is given to how these research environments shape scientists' perceptions of data sharing (dis)incentives. This paper expands on these issues of incentivizing data sharing, using data from a quantitative survey disseminated to life scientists in 13 countries in sub-Saharan Africa. This interrogated not only perceptions of data sharing amongst LMIC scientists, but also how these are connected to the research environments and daily challenges experienced by them. The paper offers a series of analysis around commonly cited (dis)incentives such as data sharing as a means of improving research visibility; sharing and funding; and online connectivity. It identifies key areas that the Open Data community need to consider if true openness in research is to be established in the Global South.

Governing Nanotechnology in a Globalized World: Cross-National Dimensions and Strategic Assessments of a Disruptive Technology

OpenAIRE

Center on Contemporary Conflict

2013-01-01

FY 2013-2014. Project Lead: Anne Clunan & Kirsten Rodine Hardy While those in the nanotechnology field emphasize the benefits for medicine, travel, and manufacturing, it is a dual-use technology that could lead to a disruptive and expensive arms race for technology dominance. Nanotechnology has significant implications for globalization, technological governance, and national sovereignty. Through a cross-national and strategic lens, the project will analyze the potential threats to nati...

Global Software Engineering

DEFF Research Database (Denmark)

Ebert, Christof; Kuhrmann, Marco; Prikladnicki, Rafael

2016-01-01

Professional software products and IT systems and services today are developed mostly by globally distributed teams, projects, and companies. Successfully orchestrating Global Software Engineering (GSE) has become the major success factor both for organizations and practitioners. Yet, more than...... and experience reported at the IEEE International Conference on Software Engineering (ICGSE) series. The outcomes of our analysis show GSE as a field highly attached to industry and, thus, a considerable share of ICGSE papers address the transfer of Software Engineering concepts and solutions to the global stage...

Cross-Border Exposures and Financial Contagion

NARCIS (Netherlands)

Degryse, H.A.; Elahi, M.A.; Penas, M.F.

2009-01-01

Integrated financial markets provide opportunities for expansion and improved risk sharing, but also pose threats of contagion risk through cross-border exposures. This paper examines cross-border contagion risk over the period 1999-2006. To that purpose we use aggregate cross-border exposures of

International Cyber Incident Repository System: Information Sharing on a Global Scale

Energy Technology Data Exchange (ETDEWEB)

Joyce, Amanda L.; Evans, PhD, Nathaniel; Tanzman, Edward A.; Israeli, Daniel

2017-02-02

According to the 2016 Internet Security Threat Report, the largest number of cyber attacks were recorded last year (2015), reaching a total of 430 million incidents throughout the world. As the number of cyber incidents increases, the need for information and intelligence sharing increases, as well. This fairly large increase in cyber incidents is driving the need for an international cyber incident data reporting system. The goal of the cyber incident reporting system is to make available shared and collected information about cyber events among participating international parties. In its 2014 report, Insurance Industry Working Session Readout Report-Insurance for CyberRelated Critical Infrastructure Loss: Key Issues, on the outcomes of a working session on cyber insurance, the U.S. Department of Homeland Security observed that “many participants cited the need for a secure method through which organizations could pool and share cyber incident information” and noted that one underwriter emphasized the importance of internationally harmonized data taxonomies. This cyber incident data reporting system could benefit all nations that take part in reporting incidents to provide a more common operating picture. In addition, this reporting system could allow for trending and anticipated attacks and could potentially benefit participating members by enabling them to get in front of potential attacks. The purpose of this paper is to identify options for consideration for such a system in fostering cooperative cyber defense.

Power sharing and transitional justice : a clash of paradigms?

OpenAIRE

Vandeginste, Stef; Sriram, Chandra Lekha

2011-01-01

Abstract: Recent peace negotiations practice has given rise to the emergence of two paradigms. In line with normative developments in global human rights protection, internationally brokered peace processes often address the options for accountability for abuses committed in the past and generally cannot include blanket amnesties. At the same time, many agreements end armed conflicts by offering power-sharing incentives for warring parties. In most cases, power-sharing arrangements are likely...

CROSS-CULTURAL ISSUES IN HRM

OpenAIRE

Bhatti, Anant Preet

2009-01-01

With the rapid increase in the globalization of business, workforces are becoming increasingly diverse and multicultural. Managing global workforces has increased pressure on Human Resource managers to recognize and adapt to cultural differences, which when ignored can result in cross-cultural misunderstandings. With the growing significance of developing economies in the global business environment, Human Resource Management is facing increased difficulty in managing cross-border cultural re...

Birefringence characteristics in sperm heads allow for the selection of reacted spermatozoa for intracytoplasmic sperm injection.

Science.gov (United States)

Gianaroli, Luca; Magli, M Cristina; Ferraretti, Anna P; Crippa, Andor; Lappi, Michela; Capitani, Serena; Baccetti, Baccio

2010-02-01

To verify clinical outcome after injection of spermatozoa that have undergone the acrosome reaction (reacted spermatozoa) vs. those still having an intact acrosome (nonreacted spermatozoa). Prospective, randomized study. Reproductive Medicine Unit, Italian Society for the Study of Reproductive Medicine, Bologna, Italy. According to a prospective randomization including 71 couples with severe male factor infertility, intracytoplasmic sperm injection (ICSI) was performed under polarized light that permitted analysis of the pattern of birefringence in the sperm head. Twenty-three patients had their oocytes injected with reacted spermatozoa, 26 patient's oocytes were injected with nonreacted spermatozoa, and in 22 patients both reacted and nonreacted spermatozoa were injected. Intracytoplasmic sperm injection was performed under polarized light to selectively inject acrosome-reacted and acrosome-nonreacted spermatozoa. Rates of fertilization, cleavage, pregnancy, implantation, and ongoing implantation. There was no effect on the fertilizing capacity and embryo development of either type of sperm, whereas the implantation rate was higher in oocytes injected with reacted spermatozoa (39.0%) vs. those injected with nonreacted spermatozoa (8.6%). The implantation rate was 24.4% in the group injected with both reacted and nonreacted spermatozoa. The delivery rate per cycle followed the same trend. Spermatozoa that have undergone the acrosome reaction seem to be more prone to supporting the development of viable ICSI embryos. Copyright 2010 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.

Event-related potentials reveal increased distraction by salient global objects in older adults

DEFF Research Database (Denmark)

Wiegand, Iris; Finke, Kathrin; Töllner, Thomas

Age-related changes in visual functions influence how older individuals perceive and react upon objects in their environment. In particular, older individuals might be more distracted by highly salient, irrelevant information. Kanizsa figures induce a ‘global precedence’ effect, which reflects...... a processing advantage for salient whole-object representations relative to configurations of local elements not inducing a global form. We investigated event-related potential (ERP) correlates of age-related decline in visual abilities, and specifically, distractibility by salient global objects in visual...

Attitudes of Health Professional Educators Toward the Use of Social Media as a Teaching Tool: Global Cross-Sectional Study

Science.gov (United States)

Henningham, Lucy; Zou, Runyu; Huang, Jessica; O'Sullivan, Elizabeth; Last, Jason; Ho, Kendall

2017-01-01

Background The use of social media in health education has witnessed a revolution within the past decade. Students have already adopted social media informally to share information and supplement their lecture-based learning. Although studies show comparable efficacy and improved engagement when social media is used as a teaching tool, broad-based adoption has been slow and the data on barriers to uptake have not been well documented. Objective The objective of this study was to assess attitudes of health educators toward social media use in education, examine differences between faculty members who do and do not use social media in teaching practice, and determine contributing factors for an increase in the uptake of social media. Methods A cross-sectional Web-based survey was disseminated to the faculty of health professional education departments at 8 global institutions. Respondents were categorized based on the frequency of social media use in teaching as “users” and “nonusers.” Users sometimes, often, or always used social media, whereas nonusers never or rarely used social media. Results A total of 270 health educators (52.9%, n=143 users and 47.0%, n=127 nonusers) were included in the survey. Users and nonusers demonstrated significant differences on perceived barriers and potential benefits to the use of social media. Users were more motivated by learner satisfaction and deterred by lack of technology compatibility, whereas nonusers reported the need for departmental and skill development support. Both shared concerns of professionalism and lack of evidence showing enhanced learning. Conclusions The majority of educators are open-minded to incorporating social media into their teaching practice. However, both users and nonusers have unique perceived challenges and needs, and engaging them to adapt social media into their educational practice will require previously unreported approaches. Identification of these differences and areas of overlap

Attitudes of Health Professional Educators Toward the Use of Social Media as a Teaching Tool: Global Cross-Sectional Study.

Science.gov (United States)

D'Souza, Karan; Henningham, Lucy; Zou, Runyu; Huang, Jessica; O'Sullivan, Elizabeth; Last, Jason; Ho, Kendall

2017-08-04

The use of social media in health education has witnessed a revolution within the past decade. Students have already adopted social media informally to share information and supplement their lecture-based learning. Although studies show comparable efficacy and improved engagement when social media is used as a teaching tool, broad-based adoption has been slow and the data on barriers to uptake have not been well documented. The objective of this study was to assess attitudes of health educators toward social media use in education, examine differences between faculty members who do and do not use social media in teaching practice, and determine contributing factors for an increase in the uptake of social media. A cross-sectional Web-based survey was disseminated to the faculty of health professional education departments at 8 global institutions. Respondents were categorized based on the frequency of social media use in teaching as "users" and "nonusers." Users sometimes, often, or always used social media, whereas nonusers never or rarely used social media. A total of 270 health educators (52.9%, n=143 users and 47.0%, n=127 nonusers) were included in the survey. Users and nonusers demonstrated significant differences on perceived barriers and potential benefits to the use of social media. Users were more motivated by learner satisfaction and deterred by lack of technology compatibility, whereas nonusers reported the need for departmental and skill development support. Both shared concerns of professionalism and lack of evidence showing enhanced learning. The majority of educators are open-minded to incorporating social media into their teaching practice. However, both users and nonusers have unique perceived challenges and needs, and engaging them to adapt social media into their educational practice will require previously unreported approaches. Identification of these differences and areas of overlap presents opportunities to determine a strategy to increase

Second law analysis of a reacting temperature dependent viscous ...

African Journals Online (AJOL)

In this paper, entropy generation during the flow of a reacting viscous fluid through an inclined Channel with isothermal walls are investigated. The coupled energy and momentum equations were solved numerically. Previous results in literature (Adesanya et al 2006 [[17]) showed both velocity and temperature have two ...

Multi-level discrepancies with sharing data on protected areas: what we have and what we need for the global village.

Science.gov (United States)

Bertzky, Monika; Stoll-Kleemann, Susanne

2009-01-01

Protected areas present a global heritage. Assessing conservation achievements in protected areas is of crucial importance with respect to the on-time delivery of international biodiversity conservation targets. However, monitoring data from publicly accessible databases for comparative studies of conservation achievements in the protected areas of the world are very scarce, if not non-existent. At first glance this is surprising because, with regards to protected areas, at least according to well established protected area management guidelines and widely accepted public mandates, a great deal of monitoring work and data gathering is to be conducted. This would imply that data on changes of biodiversity in protected areas could be expected to exist, and the constant progress in information technologies and Web tools engenders hope that some of it might even be available online for the global public. This review article presents the results of an extensive online search and review of existing monitoring data from freely accessible online databases for its use in an assessment of conservation achievements in a larger sample of protected areas. Results show two contrary sides to the status quo of accessible data from the World Wide Web for conservation science: data overkill and data scarcity with poor metadata provision. While ever more research is, in fact, based on open-access online data, such as extrapolations of species ranges used in conservation management and planning, it remains almost impossible to obtain a basic set of information for an assessment of conservation achievements within a larger number of protected areas. This awareness has triggered a detailed discussion about the discrepancies in sharing data at the level of protected areas; mismatching relationships between expected activities in protected areas and the capacity for delivering these requirements are certainly among the main challenges. In addition, the fear of data misuse potentially

Perspectives on global nursing leadership: international experiences from the field.

Science.gov (United States)

Buckner, E B; Anderson, D J; Garzon, N; Hafsteinsdóttir, T B; Lai, C K Y; Roshan, R

2014-12-01

Nursing leaders from six countries engaged in a year-long discussion on global leadership development. The purpose of these dialogues was to strengthen individual and collective capacity as nursing leaders in a global society. Field experiences in practice and education were shared. Perspectives on global leadership can strengthen nurses' contributions to practice, workplace and policy issues worldwide. Transformational leadership empowers nurses' increasing confidence. Mentoring is needed to stimulate leadership development but this is lacking in many settings where nurses practice, teach and influence policy. Organizations with global mission provide opportunity for nurses' professional growth in leadership through international dialogues. Dialogues among participants were held monthly by conference calls or videoconferences. Example stories from each participant illustrated nursing leadership in action. From these exemplars, concepts were chosen to create a framework. Emerging perspectives and leadership themes represented all contexts of practice, education, research and policy. The cultural context of each country was reflected in the examples. Themes emerged that crossed global regions and countries. Themes were creativity, change, collaboration, community, context and courage. Relationships initially formed in professional organizations can be extended to intentionally facilitate global nursing leadership development. Exemplars from the dialogues demonstrated nursing leadership in health policy development within each cultural context. Recommendations are given for infrastructure development in organizations to enhance future collaborations. © 2014 International Council of Nurses.

Big Data solution for CTBT monitoring: CEA-IDC joint global cross correlation project

Science.gov (United States)

Bobrov, Dmitry; Bell, Randy; Brachet, Nicolas; Gaillard, Pierre; Kitov, Ivan; Rozhkov, Mikhail

2014-05-01

Waveform cross-correlation when applied to historical datasets of seismic records provides dramatic improvements in detection, location, and magnitude estimation of natural and manmade seismic events. With correlation techniques, the amplitude threshold of signal detection can be reduced globally by a factor of 2 to 3 relative to currently standard beamforming and STA/LTA detector. The gain in sensitivity corresponds to a body wave magnitude reduction by 0.3 to 0.4 units and doubles the number of events meeting high quality requirements (e.g. detected by three and more seismic stations of the International Monitoring System (IMS). This gain is crucial for seismic monitoring under the Comprehensive Nuclear-Test-Ban Treaty. The International Data Centre (IDC) dataset includes more than 450,000 seismic events, tens of millions of raw detections and continuous seismic data from the primary IMS stations since 2000. This high-quality dataset is a natural candidate for an extensive cross correlation study and the basis of further enhancements in monitoring capabilities. Without this historical dataset recorded by the permanent IMS Seismic Network any improvements would not be feasible. However, due to the mismatch between the volume of data and the performance of the standard Information Technology infrastructure, it becomes impossible to process all the data within tolerable elapsed time. To tackle this problem known as "BigData", the CEA/DASE is part of the French project "DataScale". One objective is to reanalyze 10 years of waveform data from the IMS network with the cross-correlation technique thanks to a dedicated High Performance Computer (HPC) infrastructure operated by the Centre de Calcul Recherche et Technologie (CCRT) at the CEA of Bruyères-le-Châtel. Within 2 years we are planning to enhance detection and phase association algorithms (also using machine learning and automatic classification) and process about 30 terabytes of data provided by the IDC to

Shared language:Towards more effective communication.

Science.gov (United States)

Thomas, Joyce; McDonagh, Deana

2013-01-01

The ability to communicate to others and express ourselves is a basic human need. As we develop our understanding of the world, based on our upbringing, education and so on, our perspective and the way we communicate can differ from those around us. Engaging and interacting with others is a critical part of healthy living. It is the responsibility of the individual to ensure that they are understood in the way they intended.Shared language refers to people developing understanding amongst themselves based on language (e.g. spoken, text) to help them communicate more effectively. The key to understanding language is to first notice and be mindful of your language. Developing a shared language is an ongoing process that requires intention and time, which results in better understanding.Shared language is critical to collaboration, and collaboration is critical to business and education. With whom and how many people do you connect? Your 'shared language' makes a difference in the world. So, how do we successfully do this? This paper shares several strategies.Your sphere of influence will carry forward what and how you are communicating. Developing and nurturing a shared language is an essential element to enhance communication and collaboration whether it is simply between partners or across the larger community of business and customers. Constant awareness and education is required to maintain the shared language. We are living in an increasingly smaller global community. Business is built on relationships. If you invest in developing shared language, your relationships and your business will thrive.

Act local, think global

International Nuclear Information System (INIS)

Lewis, Chris; McRoberts, Doug

2002-01-01

Tip O'Neill, one of the grand old men of modem US politics, once famously remarked that all politics is local. Like most politicians who succeed on the national stage - and not just in the US - it was a truth he never lost sight of. What is true for politicians is equally true in the communications business. We may increasingly live in a global village, but successful companies - even multi-nationals - forget the importance of local and regional public relations at their peril. Think of Douglas Ivester, the CEO of Coca-Cola at the time of the 1999 Belgian contamination scandal, who allegedly reacted to first reports of the crisis by asking: 'Where the hell is Belgium?' A more appropriate question today - several years after Coke's share price toppled and the CEO was unceremoniously sacked - might be: 'Who the hell is Douglas Nester?' But - to adapt another famous phrase - the fact that communications (and marketing) professionals still need to 'act local' as much as ever before should not blind us to the growing need to 'think global'. In the nuclear industry, as in the world economy generally, increasing global integration is a reality, as are the international nature of the news media and the increasingly global nature of the anti-nuclear pressure groups. Indeed, it was the growing need for a truly global information network to counter these trends, by increasing the overall speed and accuracy of the worldwide nuclear information flow, that led the nuclear community to establish NucNet in 1991. So where exactly is the line between local and regional nuclear communications on the one hand, and global communications on the other? Is there one spin for a regional audience, and another for a global audience? This presentation proposes some guiding principles, by examining the response of nuclear communicators world-wide to the new communications agenda imposed in the wake of the September 11th suicide attacks in the US. NucNet President Doug McRoberts and Executive

Global Climate Exchange: Peer collaboration in a “Global classroom”

OpenAIRE

Korsager, Majken; Jorde, Doris; Slotta, Jim

2014-01-01

This paper reports on student peer collaboration in an online environment in an international shared curriculum, the Global Climate Exchange. Four cohorts of students (age 16 -19) from Canada, China, Norway and Sweden (n=157) were engaged in four wiki-based activities where they collaborated with peers locally and internationally. Previously, impact from Global Climate Exchange on students’ conceptual understanding was analysed, indicating a positive impact which might be explained by the amo...

Global Peace through the Global University System

Directory of Open Access Journals (Sweden)

Cengiz Hakan AYDIN

2006-01-01

Full Text Available Utopia is defined in Encarta Dictionary as “an ideal and perfect place or state, where everyone lives in harmony and everything is for the best.” Developments all around the world especially in the last decade have supported the idea that global peace is nothing but just a utopian dream. However, for centuries a group of believers have always been in search of global peace via different means. This book, titled as “Global Peace through the Global University System”, can be considered as one of the artifacts of this search.Actually this book is a collection of papers presented in working conference on the Global University System (GUS hosted by the University of Tampere, Finland in 1999. The main goal of the conference was bringing international experts to share their philosophy, past and present experiences about the GUS. The conference was held by the University of Tampere because UNESCO has an agreement with the University to establish the UNESCOChair in Global e-Learning.

Differing Event-Related Patterns of Gamma-Band Power in Brain Waves of Fast- and Slow-Reacting Subjects

Science.gov (United States)

1994-05-01

Wilhelm Wundt proposed that there are two types of subjects in sim- ple RT experiments: fast-reacting subjects, who respond before they fully...quickly as possible to auditory stimuli. This result appears to confirm long-standing speculations of Wundt that fast- and slow-reacting subjects...accord with the hypothesis of Wundt and others that slower ("sensorial") responders wait to fully perceive a stimulus and then react to their perception

Facilitating Cross-Cultural Management Education through Global Faculty Exchanges

Science.gov (United States)

Clinebell, Sharon K.; Kvedaraviciene, Ieva

2013-01-01

According to the AACSB International (Association to Advance Collegiate Schools of Business) (AACSB International, 2011), the next big transformational wave to hit business schools is globalization. Globalizing the faculty is one strategy for enhancing the globalization of business schools and using global faculty exchanges is one method to…

Emotional Eruptions, Volcanic Activity and Global Mobilities

DEFF Research Database (Denmark)

Jensen, Ole B.

2011-01-01

The eruption of Iceland’s Eyjafjallajökull volcano in April 2010 set off a number of environmental, economic and cultural effects obstructing thousands of people in the midst of their global mobility flows. It halted, as well, the exchange of goods and commodities and exposed the vulnerability...... of the global aeromobility system. In this paper an account is given of how the event was experienced by a European academic attending a number of North American conferences at precisely the time of the eruption. The paper is an attempt to describe how people reacted emotionally as well as rationally......, attempting to find strategies for coping with the consequences of the eruption....

Direct access inter-process shared memory

Science.gov (United States)

Brightwell, Ronald B; Pedretti, Kevin; Hudson, Trammell B

2013-10-22

A technique for directly sharing physical memory between processes executing on processor cores is described. The technique includes loading a plurality of processes into the physical memory for execution on a corresponding plurality of processor cores sharing the physical memory. An address space is mapped to each of the processes by populating a first entry in a top level virtual address table for each of the processes. The address space of each of the processes is cross-mapped into each of the processes by populating one or more subsequent entries of the top level virtual address table with the first entry in the top level virtual address table from other processes.

Exploring Culture Theory Global Leadership and OrganizationalBehaviour Effectiveness in Cross-cultural Communication inAsian Business Negotiations

OpenAIRE

Hoo, Pin Lick Soo

2016-01-01

While certain In international business negotiations, having the knowledge of cross-cultural communication is essential especially in global business environments and thus, many researchers have spent numerous years to investigate how culture influences Asian business negotiation which has contributed to negotiation outcome. This article provides critical insight into the theoretical link of cultural dimensions of culture for international business negotiations. The proposed model suggested i...

From conceptual pluralism to practical agreement on policy: global responsibility for global health.

Science.gov (United States)

Ruger, Jennifer Prah; Hammonds, Rachel; Ooms, Gorik; Barry, Donna; Chapman, Audrey; Van Damme, Wim

2015-10-28

As the human cost of the global economic crisis becomes apparent the ongoing discussions surrounding the post-2015 global development framework continue at a frenzied pace. Given the scale and scope of increased globalization moving forward in a post-Millennium Development Goals era, to protect and realize health equity for all people, has never been more challenging or more important. The unprecedented nature of global interdependence underscores the importance of proposing policy solutions that advance realizing global responsibility for global health. This article argues for advancing global responsibility for global health through the creation of a Global Fund for Health. It suggests harnessing the power of the exceptional response to the combined epidemics of AIDS, TB and Malaria, embodied in the Global Fund to Fight AIDS, Tuberculosis and Malaria, to realize an expanded, reconceptualized Global Fund for Health. However this proposal creates both an analytical quandary embedded in conceptual pluralism and a practical dilemma for the scope and raison d'etre of a new Global Fund for Health. To address these issues we offer a logical framework for moving from conceptual pluralism in the theories supporting global responsibility for health to practical agreement on policy to realize this end. We examine how the innovations flowing from this exceptional response can be coupled with recent ideas and concepts, for example a global social protection floor, a Global Health Constitution or a Framework Convention for Global Health, that share the global responsibility logic that underpins a Global Fund for Health. The 2014 Lancet Commission on Global Governance for Health Report asks whether a single global health protection fund would be better for global health than the current patchwork of global and national social transfers. We concur with this suggestion and argue that there is much room for practical agreement on a Global Fund for Health that moves from the

Decentralised control method for DC microgrids with improved current sharing accuracy

DEFF Research Database (Denmark)

Yang, Jie; Jin, Xinmin; Wu, Xuezhi

2017-01-01

A decentralised control method that deals with current sharing issues in dc microgrids (MGs) is proposed in this study. The proposed method is formulated in terms of ‘modified global indicator’ concept, which was originally proposed to improve reactive power sharing in ac MGs. In this work......, the ‘modified global indicator’ concept is extended to coordinate dc MGs, which aims to preserve the main features offered by decentralised control methods such as no need of communication links, central controller or knowledge of the microgrid topology and parameters. This global indicator is inserted between...... a shunt virtual resistance. The operation under multiple dc-buses is also included in order to enhance the applicability of the proposed controller. A detailed mathematical model including the effect of network mismatches is derived for analysis of the stability of the proposed controller. The feasibility...

Study on flow characteristics of chemically reacting liquid jet

International Nuclear Information System (INIS)

Hong Seon Dae; Okamoto, Koji; Takata, Takashi; Yamaguchi, Akira

2004-07-01

Tube rupture accidents in steam generators of sodium-cooled fast breeder reactors are important for safety because the rupture may propagates to neighboring tubes due to sodium-water reaction. In order to clarify the thermal-hydraulic phenomena in the accidents, the flow pattern and the interface in multi-phase flow must be investigated. The JNC cooperative research scheme on the nuclear fuel cycle with the University of Tokyo has been carried to develop a simultaneous measurement system of concentration and velocity profiles and to evaluate influence of chemical reaction on mixing phenomena. In the experiments, aqueous liquor of acetic acid and ammonium hydroxide are selected as a simulant fluid instead of liquid sodium and water vapor. The following conclusions are obtained in this research. Laser Induced Fluorescence (LIF) technique was adopted to measure reacting zone and pH distribution in chemically reacting liquid round free jet. As a result, it was found that the chemical reaction, which took place at the interface between the jet and outer flow, suppressed the mixing phenomenon (in 2001 research). Dynamic Particle Image Velocimetry (PIV) method was developed to measure instantaneous velocity profile with high temporal resolution. In the Dynamic PIV, a high-speed video camera coupled with a high-speed laser pulse generator was implemented. A time-line trend of interfacial area in the free jet was investigated with the Dynamic PIV. This technique was also applied to a complicated geometry (in 2002 research). A new algorithms for image analysis was developed to evaluated the Dynamic PIV data in detail. The characteristics of the mixing phenomenon with reacting jet such as the turbulent kinetic energy and the Reynolds stress were estimated in a spatial and temporal spectrum (in 2003 research). (author)

The Foreign Investment Risks of Chinese B Share Market

OpenAIRE

JIANG, MINCHANG

2014-01-01

The objective of this dissertation is to investigate and analyse the risks existing in Chinese B share market for foreign investment. Based on the brief history of B share market as well as background information such as characteristics of Chinese stock exchange, several areas of risks are identified as: macroeconomic risks, stock volatility and return including cross-impacts among market segmentations and different countries’ markets, financial market and currency risks, and finally the poli...

Informal milk sharing: what nurses need to know.

Science.gov (United States)

Martino, Kimberly; Spatz, Diane

2014-01-01

Human milk is the ideal food for human infants. However, some infants will be in situations wherein there is insufficient human milk to meet their needs. This article addresses formal breast milk donation (donor milk) and informal sharing of breast milk. Healthcare providers are likely to encounter families who access milk by informal breast milk sharing or cross-nursing. Both practices rely heavily on receiving human milk from women who are potentially unscreened for disease, medication, and illicit substances. Therefore, it is important for perinatal nurses to have adequate information to be able to inform these families of the risks and benefits of breast milk sharing. Two case exemplars are provided to illustrate the nuances of informal milk sharing. Implications for practice include providing families with information on health history and laboratory screening as well as safe milk-handling practices.

Narrative scenario development based on cross-impact analysis for the evaluation of global-warming mitigation options

International Nuclear Information System (INIS)

Hayashi, Ayami; Tokimatsu, Koji; Yamamoto, Hiromi; Mori, Shunsuke

2006-01-01

Social, technological, economic and environmental issues should be considered comprehensively for the evaluation of global-warming mitigation options. Existing integrated assessment models include assessment of quantitative factors; however, these models do not explicitly consider interactions among qualitative factors in the background - for example, introductions of nuclear power stations interact with social acceptability. In this paper, we applied a technological forecasting method - the cross-impact method - which explicitly deals with the relationships among relevant factors, and we then developed narrative scenarios having consistency with qualitative social contexts. An example of developed scenarios in 2050, assuming the global population and the gross domestic product are the same as those of the A1 scenario of the IPCC Special Report on Emissions Scenarios, tells us that: (1) the Internet will be extensively used in all regions; (2) the global unified market will appear; (3) regional cultures will tend to converge; (4) long-term investments (of more than 30 years) will become difficult and therefore nuclear-power stations will not increase so remarkably; (5) the self-sufficient supply and diversification of primary energy sources will not progress so rapidly; and (6) due to the widespread use of the Internet, people will be more educated in global environmental issues and environmental costs will be more socially acceptable

High-voltage shared-service line in the Stuttgart area

Energy Technology Data Exchange (ETDEWEB)

Goerler, W; Benz, A [Technische Werke der Stadt Stuttgart A.G. (F.R. Germany)

1976-01-01

In congested areas the line construction engineer has to cope with a great variety of difficulties - amenity problems, line crossings, and road crossings. The authors describe the prerequisites for and the construction of a HV shared-service line of approx. 25 km in the congested area of Stuttgart, where several three-phase and single- phase a.c. systems are run on one set of pylons.

Globalization in Japan

DEFF Research Database (Denmark)

Roesgaard, Marie Højlund

2014-01-01

Abstract for Nichibunken Copenhagen Symposium August 2012 Globalization in Japan – the case of moral education. 日本とグローバル化　－　道徳教育の件 Marie H. Roesgaard, Department of Cross-Cultural and Regional Studies, University of Copenhagen. This paper attempts to trace the history of global influence on Japan......Abstract for Nichibunken Copenhagen Symposium August 2012 Globalization in Japan – the case of moral education. 日本とグローバル化　－　道徳教育の件 Marie H. Roesgaard, Department of Cross-Cultural and Regional Studies, University of Copenhagen. This paper attempts to trace the history of global influence...... adjusting to those of the global currents that cannot be ignored. Further, I would suggest that global, or at least Western, influence is not a new thing in regard to moral education in Japan. The paper will provide an historical overview of the development of moral education since Meiji times and focus...

The role of network sharing in transforming the operator business: Impact on profitability and competition

OpenAIRE

Mölleryd, Bengt G.; Markendahl, Jan

2013-01-01

This paper focuses on network sharing on mobile networks and examines the impact on profitability and competition. Network sharing refers to that operators collaborates with its competitors on part of the production of mobile services, and it could vary from passive sharing, like sharing of sites or basic facilities, to active sharing, like radio access networks or even entire networks. The paper takes a global scope on examining the extent of network sharing. The emergence of a sector with d...

[A surface reacted layer study of titanium-zirconium alloy after dental casting].

Science.gov (United States)

Zhang, Y; Guo, T; Li, Z; Li, C

2000-10-01

To investigate the influence of the mold temperature on the surface reacted layer of Ti-Zr alloy castings. Ti-Zr alloy was casted into a mold which was made of a zircon (ZrO2.SiO2) for inner coating and a phosphate-bonded material for outer investing with a casting machine (China) designed as vacuum, pressure and centrifuge. At three mold temperatures (room temperature, 300 degrees C, 600 degrees C) the Ti-Zr alloy was casted separately. The surface roughness of the castings was calculated by instrument of smooth finish (China). From the surface to the inner part the Knoop hardness and thickness in reacted layer of Ti-Zr alloy casting was measured. The structure of the surface reacted layer was analysed by SEM. Elemental analyses of the interfacial zone of the casting was made by element line scanning observation. The surface roughness of the castings was increased significantly with the mold temperature increasing. At a higher mold temperature the Knoop hardness of the reactive layer was increased. At the three mold temperature the outmost surface was very hard, and microhardness data decreased rapidly where they reached constant values. The thickness was about 85 microns for castings at room temperature and 300 degrees C, 105 microns for castings at 600 degrees C. From the SEM micrograph of the Ti-Zr alloy casting, the surface reacted layer could be divided into three different layers. The first layer was called non-structure layer, which thickness was about 10 microns for room temperature group, 20 microns for 300 degrees C and 25 microns for 600 degrees C. The second layer was characterized by coarse-grained acicular crystal, which thickness was about 50 microns for three mold temperatures. The third layer was Ti-Zr alloy. The element line scanning showed non-structure layer with higher level of element of O, Al, Si and Zr, The higher the mold temperature during casting, the deeper the Si permeating and in the second layer the element Si could also be found

Knowledge Sharing for Common Understanding of Technical Specifications Through Artifactual Culture

DEFF Research Database (Denmark)

Zahedi, Mansooreh; Babar, Muhammad Ali

2014-01-01

Context: Software engineering is a knowledge intensive activity that is supported by documenting and sharing the required knowledge through a wide variety of artifacts. Global Software Development (GSD) teams heavily rely on artifacts as a vital means of knowledge sharing. However, there is little...... empirical knowledge about the key reasons and practices of using artifacts in GSD for knowledge sharing to support common understanding of technical specifications. Objective: This study aims at empirically studying the key motivators, practices, and drawbacks of artifact-based knowledge sharing...... specification knowledge. We also present the practices that make up the artifact-based knowledge sharing system in the studied case. Finally, we shed some light on the caveats of knowledge sharing practices adopted by the studied company. The findings can provide useful insights into the artifact...

Experimental thermodynamics experimental thermodynamics of non-reacting fluids

CERN Document Server

Neindre, B Le

2013-01-01

Experimental Thermodynamics, Volume II: Experimental Thermodynamics of Non-reacting Fluids focuses on experimental methods and procedures in the study of thermophysical properties of fluids. The selection first offers information on methods used in measuring thermodynamic properties and tests, including physical quantities and symbols for physical quantities, thermodynamic definitions, and definition of activities and related quantities. The text also describes reference materials for thermometric fixed points, temperature measurement under pressures, and pressure measurements. The publicatio

Cross-sensitization patterns in guinea pigs between cinnamaldehyde, cinnamyl alcohol and cinnamic acid

DEFF Research Database (Denmark)

Weibel, H; Hansen, J; Andersen, Klaus Ejner

1989-01-01

Guinea pig maximization tests (GPMT) were performed with cinnamon substances. There was a certain degree of cross-reactivity between cinnamaldehyde, cinnamyl alcohol and cinnamic acid as animals sensitized to cinnamaldehyde reacted to the challenge with the three substances. Animals sensitized to...

Employee participation in knowledge sharing and change solutions through enterprise social media

DEFF Research Database (Denmark)

Andersen, Mona Agerholm; Agerdal-Hjermind, Annette; Valentini, Chiara

Purpose - This paper explores the relationship between the participative style of the immediate manager and employees’ motivation to participate on enterprise social media both in daily knowledge sharing activities and in relation to organizational change solutions. Methodology - This project.......046). Findings - The data shows a positive relationship between the participative style of the immediate manager and the employees’ motivation to participate on enterprise social media both in daily knowledge sharing activities and in creating and discussing change solutions. Key words: Internal social media...... is based on a quantitative study in a global Danish company with approximately 18,000 employees worldwide. The company has a strategic focus on implementing social collaboration platforms to create a global working culture. An online survey was conducted globally and a total of 1.046 employees replied (n=1...

Cross System Extensions (CSE) experience

International Nuclear Information System (INIS)

Johnston, T.Y.

1990-08-01

Cross System Extension (CSE) provides VM/XA systems with the ability to share minidisks and spool in loosely coupled environment. CSE will also cooperate with the VM/HPO Inter System Facility (ISF) in sharing minidisks between VM/XA and VM/HPO to XA, reliability of CSE, and some operational considerations when running with it

An Analysis of Introduction of Cloud Computing Affects the Corporate IT Shared Services Business Model

OpenAIRE

Liew, Chin Hoi

2013-01-01

I.T. Shared Services is a global trend that is adopted by many companies’ especially global multi-national companies. The initial drivers of such services company setup is to around standardizing, consolidating and centrally manage I.T, this move would eventually bring cost reduction and saving to the company in long run. Today, business organizations are increasingly leveraging Shared Services to manage their I.T Infrastructure and application services with expectation further cost reduction...

Direct numerical simulation of turbulent, chemically reacting flows

Science.gov (United States)

Doom, Jeffrey Joseph

This dissertation: (i) develops a novel numerical method for DNS/LES of compressible, turbulent reacting flows, (ii) performs several validation simulations, (iii) studies auto-ignition of a hydrogen vortex ring in air and (iv) studies a hydrogen/air turbulent diffusion flame. The numerical method is spatially non-dissipative, implicit and applicable over a range of Mach numbers. The compressible Navier-Stokes equations are rescaled so that the zero Mach number equations are discretely recovered in the limit of zero Mach number. The dependent variables are co--located in space, and thermodynamic variables are staggered from velocity in time. The algorithm discretely conserves kinetic energy in the incompressible, inviscid, non--reacting limit. The chemical source terms are implicit in time to allow for stiff chemical mechanisms. The algorithm is readily applicable to complex chemical mechanisms. Good results are obtained for validation simulations. The algorithm is used to study auto-ignition in laminar vortex rings. A nine species, nineteen reaction mechanism for H2/air combustion proposed by Mueller et al. [37] is used. Diluted H 2 at ambient temperature (300 K) is injected into hot air. The simulations study the effect of fuel/air ratio, oxidizer temperature, Lewis number and stroke ratio (ratio of piston stroke length to diameter). Results show that auto--ignition occurs in fuel lean, high temperature regions with low scalar dissipation at a 'most reactive' mixture fraction, zeta MR (Mastorakos et al. [32]). Subsequent evolution of the flame is not predicted by zetaMR; a most reactive temperature TMR is defined and shown to predict both the initial auto-ignition as well as subsequent evolution. For stroke ratios less than the formation number, ignition in general occurs behind the vortex ring and propagates into the core. At higher oxidizer temperatures, ignition is almost instantaneous and occurs along the entire interface between fuel and oxidizer. For stroke

Econometric Analysis of the Market Share Attraction Model

NARCIS (Netherlands)

D. Fok (Dennis); Ph.H.B.F. Franses (Philip Hans); R. Paap (Richard)

2001-01-01

textabstractMarket share attraction models are useful tools for analyzing competitive structures. The models can be used to infer cross-effects of marketing-mix variables, but also the own effects can be adequately estimated while conditioning on competitive reactions. Important features of

From Risks to Shared Value? Corporate Strategies in Building a Global Water Accounting and Disclosure Regime

Directory of Open Access Journals (Sweden)

Marco A. Daniel

2012-10-01

Full Text Available The current debate on water accounting and accountability among transnational actors such as corporations and NGOs is likely to contribute to the emergence of a global water governance regime. Corporations within the food and beverage sector (F-B are especially vulnerable to water risks; therefore, in this article we analyse motivations and strategies of the major F-B corporations participating in the debate and developing different water accounting, disclosure and risk-assessment tools. Neo-institutionalism and neo-Gramscian regime theory provide the basis for our framework to analyse the discursive, material and organisational corporate water strategies. Findings based on an analysis of the chosen F-B corporations’ sustainability reports and interviews with key informants suggest that the corporations share similar goals and values with regard to the emerging regime. They seek a standardisation that is practical and supportive in improving their water efficiency and communication with stakeholders. This indicates that some harmonisation has taken place over time and new actors have been pursuing the path of the pioneering companies, but the lead corporations are also differentiating their strategies, thus engaging in hegemonic positioning. However, so far the plethora of NGO-driven accountability initiatives and tools has fragmented the field more than 'war of position' amongst the corporations. Furthermore, several companies claim to have proceeded from internal water-risk management to reducing risks throughout their value chains and watersheds. As a result they are 'creating shared value' with stakeholders, and potentially manifesting an emergent paradigm that goes beyond a private regime framework. Nevertheless, in the absence of verification schemes, questions of sustainability and legitimacy of such actions on the ground prevail and remain a topic for further research.

Shared and non-shared antigens from three different extracts of the metacestode of Echinococcus granulosus

Directory of Open Access Journals (Sweden)

David Carmena

2005-12-01

Full Text Available Hydatid cyst fluid (HCF, somatic antigens (S-Ag and excretory-secretory products (ES-Ag of Echinococcus granulosus protoscoleces are used as the main antigenic sources for immunodiagnosis of human and dog echinococcosis. In order to determine their non-shared as well as their shared antigenic components, these extracts were studied by ELISA-inhibition and immunoblot-inhibition. Assays were carried out using homologous rabbit polyclonal antisera, human sera from individuals with surgically confirmed hydatidosis, and sera from dogs naturally infected with E. granulosus. High levels of cross-reactivity were observed for all antigenic extracts, but especially for ES-Ag and S-Ag. Canine antibodies evidenced lesser avidity for their specific antigens than antibodies from human origin. The major antigenic components shared by HCF, S-Ag, and ES-Ag have apparent molecular masses of 4-6, 20-24, 52, 80, and 100-104 kDa, including doublets of 41/45, 54/57, and 65/68 kDa. Non-shared polypeptides of each antigenic extract of E. granulosus were identified, having apparent masses of 108 and 78 kDa for HCF, of 124, 94, 83, and 75 kDa for S-Ag, and of 89, 66, 42, 39, 37, and 35 kDa for ES-Ag.

Does the StartReact Effect Apply to First-Trial Reactive Movements?

Directory of Open Access Journals (Sweden)

Katrin Sutter

Full Text Available StartReact is the acceleration of reaction time by a startling acoustic stimulus (SAS. The SAS is thought to release a pre-prepared motor program. Here, we investigated whether the StartReact effect is applicable to the very first trial in a series of repeated unpractised single-joint movements.Twenty healthy young subjects were instructed to perform a rapid ankle dorsiflexion movement in response to an imperative stimulus. Participants were divided in two groups of ten. Both groups performed 17 trials. In one group a SAS (116 dB was given in the first trial, whereas the other group received a non-startling sound (70 dB as the first imperative stimulus. In the remaining 16 trials, the SAS was given as the imperative stimulus in 25% of the trials in both groups. The same measurement was repeated one week later, but with the first-trial stimuli counterbalanced between groups.When a SAS was given in the very first trial, participants had significantly shorter onset latencies compared to first-trial responses to a non-startling stimulus. Succeeding trials were significantly faster compared to the first trial, both for trials with and without a SAS. However, the difference between the first and succeeding trials was significantly larger for responses to a non-startling stimulus compared to responses triggered by a SAS. SAS-induced acceleration in the first trial of the second session was similar to that in succeeding trials of session 1.The present results confirm that the StartReact phenomenon also applies to movements that have not yet been practiced in the experimental context. The excessive SAS-induced acceleration in the very first trial may be due to the absence of integration of novel context-specific information with the existing motor memory for movement execution. Our findings demonstrate that StartReact enables a rapid release of motor programs in the very first trial also without previous practice, which might provide a behavioural

Global Warming: The Complete Briefing (Second Edition)

Science.gov (United States)

Hartmann, Dennis L.

Enough coal exists to sustain world energy consumption growth through at least the end of the next century. If fossil carbon fuel consumption continues to increase at current rates, however, atmospheric carbon dioxide concentrations will likely more than double, probably leading to significant warming of global climate, shifts in regional climates, and sea-level rise. Scientists and citizens throughout the world are discussing what should be done about the effects of our energy economy on the global environment.The issue is very broad and engaging, ranging from basic issues of geoscience to economics to fundamental value systems, and it has mobilized great economic interests and concern for our global environment. We live in an interesting time when human activities have begun to compete with the global capacities of Earth to recycle the elements of life. In the coming years, we will see how the world community reacts to this challenge, and what combination of conservation, technological development, and adaptation is ultimately adopted.

When Going Global Isn't Enough.

Science.gov (United States)

Randolph, Benton

1990-01-01

The traditional multinational approach to business strategy and human resource management, as well as the global approach, are not effective in a world no longer insular. A transnational approach requires global strategy and perspective, local responsiveness and flexibility, teamwork, shared responsibility, and empowered and innovative workers.…

Cross Institutional Cooperation on a Shared Bit Repository

DEFF Research Database (Denmark)

Zierau, Eld; Kejser, Ulla Bøgvad

2013-01-01

This paper explores how independent institutions, such as archives and libraries, can cooperate on managing a shared bit repository with bit preservation, in order to use their resources for preservation in a more cost-effective way. It uses the OAIS Reference Model to provide a framework...... for systematically analysing institutions technical and organisational requirements for a remote bit repository. Instead of viewing a bit repository simply as Archival Storage for the institutions repositories, we argue for viewing it as consisting of a subset of functions from all entities defined by the OAIS...... Reference Model. The work is motivated by and used in a current Danish feasibility study for establishing a national bit repository. The study revealed that depending on their missions and the collections they hold, the institutions have varying requirements e.g. for bit safety, accessibility...

Cross Institutional Cooperation on a Shared Bit Repository

DEFF Research Database (Denmark)

Zierau, Eld; Kejser, Ulla Bøgvad

2010-01-01

This paper explores how independent institutions, such as archives and libraries, can cooperate on managing a shared bit repository with bit preservation in order to use their resources for preservation n in a more cost-effective way. It uses the OAIS Reference Model to provide a framework...... for systematically analysing the technical and organizational requirements of institutions for a remote bit repository. Instead of viewing a bit repository simply as Archival Storage for the institutions’ repositories, we argue for viewing it as consisting of a subset of functions from all entities defined...... by the OAIS Reference Model. The work is motivated by and used in a current Danish feasibility study for establishing a national bit repository. The study revealed that depending on their missions and the collections they hold, the institutions have varying requirements, such as for bit safety, accessibility...

Charged Triazole Cross-Linkers for Hyaluronan-Based Hybrid Hydrogels

Directory of Open Access Journals (Sweden)

Maike Martini

2016-09-01

Full Text Available Polyelectrolyte hydrogels play an important role in tissue engineering and can be produced from natural polymers, such as the glycosaminoglycan hyaluronan. In order to control charge density and mechanical properties of hyaluronan-based hydrogels, we developed cross-linkers with a neutral or positively charged triazole core with different lengths of spacer arms and two terminal maleimide groups. These cross-linkers react with thiolated hyaluronan in a fast, stoichiometric thio-Michael addition. Introducing a positive charge on the core of the cross-linker enabled us to compare hydrogels with the same interconnectivity, but a different charge density. Positively charged cross-linkers form stiffer hydrogels relatively independent of the size of the cross-linker, whereas neutral cross-linkers only form stable hydrogels at small spacer lengths. These novel cross-linkers provide a platform to tune the hydrogel network charge and thus the mechanical properties of the network. In addition, they might offer a wide range of applications especially in bioprinting for precise design of hydrogels.

A critical appraisal of a further three new commercial digoxin radioimmunoassay kits with reference to cross-reacting substances

International Nuclear Information System (INIS)

Wood, W.G.; Wachter, C.

1979-01-01

A further 3 digoxin radioimmunoassay (RIA) kits have been evaluated for performance and cross-reaction with digitoxin, spironolactone, canrenone and furosemide (Lasix-Hoechst). Effects of serum protein concentrations have also been tested. The kits tested were from the following manufacturers: A) Diagnostic Products Corporation Digoxin RIA Kit. B) Byk-Mallinckrodt SPAC Digoxin Kit. C) Boehringer-Mannheim Digoxin RIA Kit. All kits used a 125 I-labelled tracer. Kit A used a conventional liquid phase system using double-antibody separation for bound and free drug. Kits B and C used a solid-phase antibody coated tube method. All kits showed a lower cross-reaction to digitoxin than quoted by the manufacturer. Cross-reaction to spironolactone (Aldactone - Boehringer-Mannheim) was less than 1.50 nmol/l at a serum concentration of 125 mg/l Aldactone in all 3 kits. The cross-reaction to canrenone was somewhat higher, 5.2 nmol/l 'digoxin' being measured in one kit at a serum canrenone concentration of 125 mg/l. There was no cross-reaction with furosemide in any kit, even at a serum concentration of 5 g/l. The coated-tube assays were affected by serum albumin and globulin concentration changes, one kit showing a difference of over 50% binding in the range 1-20% albumin. The double-antibody kit did not show dependence on the concentration of these proteins. All kits measured digoxin with good reproducibility in the range 0.40-10.0 nmol/l. (orig.) [de

Low Mach number asymptotics for reacting compressible fluid flows

Czech Academy of Sciences Publication Activity Database

Feireisl, Eduard; Petzeltová, Hana

2010-01-01

Roč. 26, č. 2 (2010), s. 455-480 ISSN 1078-0947 R&D Projects: GA ČR GA201/05/0164 Institutional research plan: CEZ:AV0Z10190503 Keywords : low Mach number * Navier-Stokes-Fourier system * reacting fluids Subject RIV: BA - General Mathematics Impact factor: 0.986, year: 2010 http://www.aimsciences.org/journals/displayArticles.jsp?paperID=4660

Identification of a cross-reactive allergen (presumably tropomyosin) in shrimp, mite and insects

NARCIS (Netherlands)

Witteman, A. M.; Akkerdaas, J. H.; van Leeuwen, J.; van der Zee, J. S.; Aalberse, R. C.

1994-01-01

A monoclonal antibody to Dermatophagoides pteronyssinus is described that cross-reacts with an IgE-binding antigen present in insects, Crustacea (e.g. shrimp) and other invertebrates. By means of sodium dodecyl sulfate-polyacrylamide gel electrophoresis, gel filtration and immunofluorescence it was

From European Union to World Union: Building Effective and Democratic Global Governance

Directory of Open Access Journals (Sweden)

John McClintock

2012-04-01

Full Text Available Sovereignty-sharing has placed European countries in a position to resolve their common problems through law, not war. As a result, the EU member states now live in peace together and take peace, justice and order for granted. The system of global governance is dysfunctional – some states are failing and the Security Council lacks legitimacy. Humanity does not have a mechanism to resolve its global problems through law, making it difficult – if not impossible – to resolve global problems such as famine, hunger, climate change, war and terrorism, nuclear proliferation, regulation of corporations – including banks, destruction of fish stocks, and population. Sharing of sovereignty at the global level can address these problems, starting in the area of food security, then proceeding to climate management and other fields. Shared sovereignty can eliminate famine and hunger globally.

Graduating to Postdoc: Information-Sharing in Support of Organizational Structures and Needs

Science.gov (United States)

Keller, Richard M.; Lucas, Paul J.; Compton, Michael M.; Stewart, Helen J.; Baya, Vinod; DelAlto, Martha

1999-01-01

The deployment of information-sharing systems in large organizations can significantly impact existing policies and procedures with regard to authority and control over information. Unless information-sharing systems explicitly support organizational structures and needs, these systems will be rejected summarily. The Postdoc system is a deployed Web-based information-sharing system created specifically to address organizational needs. Postdoc contains various organizational support features including a shared, globally navigable document space, as well as specialized access control, distributed administration, and mailing list features built around the key notion of hierarchical group structures. We review successes and difficulties in supporting organizational needs with Postdoc

Supporting the development of shared understanding in distributed design teams

DEFF Research Database (Denmark)

Cash, Philip; Dekoninck, Elies A; Ahmed-Kristensen, Saeema

2017-01-01

Distributed teams are an increasingly common feature of engineeringdesign work. One key factor in the success of these teams isthe development of short- and longer-term shared understanding.A lack of shared understanding has been recognized as a significantchallenge, particularly in the context o...... directly comparing homogeneous and heterogeneousteams in the engineering design context. This has implicationsfor how distributed teams can be more effectively supportedin practice, as well as how shared understanding can be facilitated inengineering design.......Distributed teams are an increasingly common feature of engineeringdesign work. One key factor in the success of these teams isthe development of short- and longer-term shared understanding.A lack of shared understanding has been recognized as a significantchallenge, particularly in the context...... of globally distributed engineeringactivities. A major antecedent for shared understanding isquestion asking and feedback. Building on question-asking theorythis work uses a quasi-experimental study to test the impact of questioningsupport on homogeneous and heterogeneous teams. Theresults show significant...

Molecular Simulation of Reacting Systems; TOPICAL

International Nuclear Information System (INIS)

THOMPSON, AIDAN P.

2002-01-01

The final report for a Laboratory Directed Research and Development project entitled, Molecular Simulation of Reacting Systems is presented. It describes efforts to incorporate chemical reaction events into the LAMMPS massively parallel molecular dynamics code. This was accomplished using a scheme in which several classes of reactions are allowed to occur in a probabilistic fashion at specified times during the MD simulation. Three classes of reaction were implemented: addition, chain transfer and scission. A fully parallel implementation was achieved using a checkerboarding scheme, which avoids conflicts due to reactions occurring on neighboring processors. The observed chemical evolution is independent of the number of processors used. The code was applied to two test applications: irreversible linear polymerization and thermal degradation chemistry

AB027. Developing capacity for variant data sharing in low and middle income countries: HVP’s Global Globin 2020 Challenge

Science.gov (United States)

Robinson, Helen M.

2015-01-01

The hemoglobinopathies, collectively, are cause for significant morbidity and mortality. Children are the most severely affected. Despite much of the genetics and biology of hemoglobinopathies being known for a long time, and being used successfully in some countries to systematically reduce burden of disease, many low and medium income countries remain practically untouched by recent developments in human genomics involving the systematic collection and sharing of variation data to fighting hemoglobinopathies (notably thalassaemias and sickle cell disease, but also G6PD). Commitment to systematic variant data collection is increasing, but this is occurring mostly in high-income countries where much of the diagnosis and testing takes place. There is a risk that countries with the highest burden of these diseases are being left behind in a form of “genomic divide”. Capacity to generate quality data on variants, to store this information so that it can be shared internationally, needs to be built in these countries. Tackling hemoglobinopathies is an ideal entry point for these countries to develop the necessary infrastructure and expertise that can expand into other areas of health. This genomic capacity will enable building: (I) the genetic evidence base for better management of delivery of local treatment, care and eventually even cure; (II) a foundation for genomic medicine by working with national, regional and local health care professionals to raise public awareness of the genetic basis of hemoglobinopathies. Global Globin 2020 Challenge has been initiated with two goals: (I) to see growth in the quality and quantity of curated inputs into internationally recognized genetic databases from low- and middle-income countries participating in the project, and to harmonize the sharing of all relevant variant data between countries in accordance with international best practice that integrates all the relevant ethical and regulatory frameworks and policies

TCRs Used in Cancer Gene Therapy Cross-React with MART-1/Melan-A Tumor Antigens via Distinct Mechanisms

Energy Technology Data Exchange (ETDEWEB)

Borbulevych, Oleg Y.; Santhanagopolan, Sujatha M.; Hossain, Moushumi; Baker, Brian M. (Notre)

2013-09-18

T cells engineered to express TCRs specific for tumor Ags can drive cancer regression. The first TCRs used in cancer gene therapy, DMF4 and DMF5, recognize two structurally distinct peptide epitopes of the melanoma-associated MART-1/Melan-A protein, both presented by the class I MHC protein HLA-A*0201. To help understand the mechanisms of TCR cross-reactivity and provide a foundation for the further development of immunotherapy, we determined the crystallographic structures of DMF4 and DMF5 in complex with both of the MART-1/Melan-A epitopes. The two TCRs use different mechanisms to accommodate the two ligands. Although DMF4 binds the two with a different orientation, altering its position over the peptide/MHC, DMF5 binds them both identically. The simpler mode of cross-reactivity by DMF5 is associated with higher affinity toward both ligands, consistent with the superior functional avidity of DMF5. More generally, the observation of two diverging mechanisms of cross-reactivity with the same Ags and the finding that TCR-binding orientation can be determined by peptide alone extend our understanding of the mechanisms underlying TCR cross-reactivity.

Adverse selection without single crossing

DEFF Research Database (Denmark)

Schottmüller, Christoph

2015-01-01

The single-crossing assumption simplifies the analysis of screening models as local incentive compatibility becomes sufficient for global incentive compatibility. If single crossing is violated, global incentive compatibility constraints have to be taken into account. This paper studies monotone...... solutions in a screening model that allows a one-time violation of single crossing. The results show that local and non-local incentive constraints distort the solution in opposite directions. Therefore, the optimal decision might involve distortions above as well as below the first-best decision...

Eyes wide open: an essay on developing an engaged awareness in global medicine and public health.

Science.gov (United States)

Ventres, William B; Fort, Meredith P

2014-10-28

There is a growing understanding of the role social determinants such as poverty, gender discrimination, racial prejudice, and economic inequality play on health and illness. While these determinants and effects may be challenging to identify in parts of high-income countries, they are patently obvious in many other areas of the world. How we react to these determinants and effects depends on what historical, cultural, ideological, and psychological characteristics we bring to our encounters with inequity, as well as how our feelings and thoughts inform our values and actions. To address these issues, we share a series of questions we have asked ourselves-United States' citizens with experience living and working in Central America-in relation to our encounters with inequity. We offer a conceptual framework for contemplating responses in hopes of promoting among educators and practitioners in medicine and public health an engaged awareness of how our every day work either perpetuates or breaks down barriers of social difference. We review key moments in our own experiences as global health practitioners to provide context for these questions. Introspective reflection can help professionals in global medicine and public health recognize the dynamic roles that they play in the world. Such reflection can bring us closer to appreciating the forces that have worked both for and in opposition to global health, human rights, and well-being. It can help us recognize how place, time, environment, and context form the social determination of health. It is from this holistic perspective of social relations that we can work to effect fair, equitable, and protective environments as they relate to global medicine and public health.

Monoclonal antibodies reactive with common tumor antigens on UV-induced tumors also react with hyperplastic UV-irradiated skin

International Nuclear Information System (INIS)

Spellman, C.W.; Beauchamp, D.A.

1986-01-01

Most murine skin tumors induced by ultraviolet light (UVB, 280-340 nm) can be successfully transplanted only into syngeneic hosts that have received subcarcinogenic doses of UVB. The tumor susceptible state is long-lived and mediated by T suppressor cells that control effector responses against common antigens on UV-induced tumors. Because antigen specific suppression arises prior to the appearance of a tumor, questions arise about the source of the original antigen. They have previously reported transplantation studies indicating that UV-irradiated skin is antigenically cross-reactive with UV-induced tumors. They now report on flow cytometry analyses showing that a series of MoAb reactive with common antigens expressed by UV-induced tumors are also reactive on cells from UV-irradiated skin. Various antigens appear at different times in the UV irradiation scheme, and some persist while others are transient. They speculate that the common antigens detected may be the ones to which functional suppression is directed. If true, these results suggest that successful tumors need not escape host defenses to emerge. Rather, tumors may arise and grow progressively if they express antigens that cross-react with specificities to which the host has previously mounted a suppressive response

Rule-Based Multidisciplinary Tool for Unsteady Reacting Real-Fluid Flows, Phase I

Data.gov (United States)

National Aeronautics and Space Administration — A design and analysis computational tool is proposed for simulating unsteady reacting flows in combustor devices used in reusable launch vehicles. Key aspects...

Global Operations Networks

DEFF Research Database (Denmark)

In the current context of global economic liberalisation and technological advancements, industrial companies are less likely to generate value in the traditional vertically integrated chain. Instead, they are doing so by means of elaborate cross-border and cross-organisational networks. As a rule......, these networks are configured on a global basis and consist of diverse and interdependent affiliates (linked both through ownership and non-equity relationships), which are engaged in an exchange of goods, services and information. The Scandinavian context is no exception to this trend. Nevertheless......, international comparative studies providing comprehensive insights from it are still rare. With the objective of bridging this gap, Global Operations Networks (GONE) project (sponsored by the Danish Research Council) brought together numerous academic and industrial partners from Denmark, Sweden and Finland...

Double shock experiments and reactive flow modeling on LX-17 to understand the reacted equation of state

International Nuclear Information System (INIS)

Vandersall, Kevin S; Garcia, Frank; Fried, Laurence E; Tarver, Craig M

2014-01-01

Experimental data from measurements of the reacted state of an energetic material are desired to incorporate reacted states in modeling by computer codes. In a case such as LX-17 (92.5% TATB and 7.5% Kel-F by weight), where the time dependent kinetics of reaction is still not fully understood and the reacted state may evolve over time, this information becomes even more vital. Experiments were performed to measure the reacted state of LX-17 using a double shock method involving the use of two flyer materials (with known properties) mounted on the projectile that send an initial shock through the material close to or above the Chapman-Jouguet (CJ) state followed by a second shock at a higher magnitude into the detonated material. By measuring the parameters of the first and second shock waves, information on the reacted state can be obtained. The LX-17 detonation reaction zone profiles plus the arrival times and amplitudes of reflected shocks in LX-17 detonation reaction products were measured using Photonic Doppler Velocimetry (PDV) probes and an aluminum foil coated LiF window. A discussion of this work will include the experimental parameters, velocimetry profiles, data interpretation, reactive CHEETAH and Ignition and Growth modeling, as well as detail on possible future experiments.

Emerging Geospatial Sharing Technologies in Earth and Space Science Informatics

Science.gov (United States)

Singh, R.; Bermudez, L. E.

2013-12-01

Emerging Geospatial Sharing Technologies in Earth and Space Science Informatics The Open Geospatial Consortium (OGC) mission is to serve as a global forum for the collaboration of developers and users of spatial data products and services, and to advance the development of international standards for geospatial interoperability. The OGC coordinates with over 400 institutions in the development of geospatial standards. In the last years two main trends are making disruptions in geospatial applications: mobile and context sharing. People now have more and more mobile devices to support their work and personal life. Mobile devices are intermittently connected to the internet and have smaller computing capacity than a desktop computer. Based on this trend a new OGC file format standard called GeoPackage will enable greater geospatial data sharing on mobile devices. GeoPackage is perhaps best understood as the natural evolution of Shapefiles, which have been the predominant lightweight geodata sharing format for two decades. However the format is extremely limited. Four major shortcomings are that only vector points, lines, and polygons are supported; property names are constrained by the dBASE format; multiple files are required to encode a single data set; and multiple Shapefiles are required to encode multiple data sets. A more modern lingua franca for geospatial data is long overdue. GeoPackage fills this need with support for vector data, image tile matrices, and raster data. And it builds upon a database container - SQLite - that's self-contained, single-file, cross-platform, serverless, transactional, and open source. A GeoPackage, in essence, is a set of SQLite database tables whose content and layout is described in the candidate GeoPackage Implementation Specification available at https://portal.opengeospatial.org/files/?artifact_id=54838&version=1. The second trend is sharing client 'contexts'. When a user is looking into an article or a product on the web

Handbook of Global and Multicultural Negotiation

CERN Document Server

Moore, Christopher W

2010-01-01

Handbook of Global and Multicultural Negotiation provides advice and strategies for effective cross-cultural negotiations. Written from a multicultural perspective, this guidebook explores cross-cultural communication for problem solving and negotiations. This resource includes real-life stories and examples compiled from over thirty years of domestic and global experience from both authors, including Chris Moore, a well-known international negotiator and best selling author. This step-by-step guide to negotiation provides practical recommendations, advice, and globally proven strategies to pr

Social capital and knowledge sharing: effects on patient safety.

Science.gov (United States)

Chang, Chia-Wen; Huang, Heng-Chiang; Chiang, Chi-Yun; Hsu, Chiu-Ping; Chang, Chia-Chen

2012-08-01

This article is a report on a study that empirically examines the influence of social capital on knowledge sharing and the impact of knowledge sharing on patient safety. Knowledge sharing is linked to many desirable managerial outcomes, including learning and problem-solving, which are essential for patient safety. Rather than studying the tangible effects of rewards, this study examines whether social capital (including social interaction, trust and shared vision) directly supports individual knowledge sharing in an organization. This cross-sectional study analysed data collected through a questionnaire survey of nurses from a major medical centre in northern Taiwan. The data were collected over a 9-month period from 2008 to 2009. The data analysis was conducted using the Partial Least Squares Graph v3.0 program to evaluate the measurement properties and the structural relationships specified in the research model. Based on a large-scale survey, empirical results indicate that Registered Nurses' perceptions of trust and shared vision have statistically significant and direct effects on knowledge sharing. In addition, knowledge sharing is significantly and positively associated with patient safety. The findings suggest that hospital administrators should foster group trust and initiate a common vision among Registered Nurses. In addition, administrators and chief knowledge officers of hospitals should encourage positive intentions towards knowledge sharing. © 2011 The Authors. Journal of Advanced Nursing © 2011 Blackwell Publishing Ltd.

Global teaching and training initiatives for emerging cohort studies

Directory of Open Access Journals (Sweden)

Jessica K. Paulus

2012-09-01

Full Text Available A striking disparity exists across the globe, with essentially no large-scale longitudinal studies ongoing in regions that will be significantly affected by the oncoming non-communicable disease epidemic. The successful implementation of cohort studies in most low-resource research environments presents unique challenges that may be aided by coordinated training programs. Leaders of emerging cohort studies attending the First World Cohort Integration Workshop were surveyed about training priorities, unmet needs and potential cross-cohort solutions to these barriers through an electronic pre-workshop questionnaire and focus groups. Cohort studies representing India, Mexico, Nigeria, South Africa, Sweden, Tanzania and Uganda described similar training needs, including on-the-job training, data analysis software instruction, and database and bio-bank management. A lack of funding and protected time for training activities were commonly identified constraints. Proposed solutions include a collaborative cross-cohort teaching platform with web-based content and interactive teaching methods for a range of research personnel. An international network for research mentorship and idea exchange, and modifying the graduate thesis structure were also identified as key initiatives. Cross-cohort integrated educational initiatives will efficiently meet shared needs, catalyze the development of emerging cohorts, speed closure of the global disparity in cohort research, and may fortify scientific capacity development in low-resource settings.

Numerical simulation of low Mach number reacting flows

International Nuclear Information System (INIS)

Bell, J B; Aspden, A J; Day, M S; Lijewski, M J

2007-01-01

Using examples from active research areas in combustion and astrophysics, we demonstrate a computationally efficient numerical approach for simulating multiscale low Mach number reacting flows. The method enables simulations that incorporate an unprecedented range of temporal and spatial scales, while at the same time, allows an extremely high degree of reaction fidelity. Sample applications demonstrate the efficiency of the approach with respect to a traditional time-explicit integration method, and the utility of the methodology for studying the interaction of turbulence with terrestrial and astrophysical flame structures

Association between serum organochlorines and global methylation level of leukocyte DNA among Japanese women: a cross-sectional study

Energy Technology Data Exchange (ETDEWEB)

Itoh, Hiroaki [Department of Epidemiology and Environmental Health, Juntendo University Faculty of Medicine, 2-1-1 Hongo, Bunkyo-ku, Tokyo 113–8421 Japan (Japan); Iwasaki, Motoki, E-mail: moiwasak@ncc.go.jp [Epidemiology Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5-1-1 Tsukiji, Chuo-ku, Tokyo 104–0045 Japan (Japan); Kasuga, Yoshio [Department of Surgery, Nagano Matsushiro General Hospital, 183 Matsushiro, Matsushiro-cho, Nagano City, Nagano Prefecture 381–1231 Japan (Japan); Yokoyama, Shiro; Onuma, Hiroshi [Department of Breast and Thyroid Surgery, Nagano Red Cross Hospital, 5-22-1 Wakasato, Nagano City, Nagano Prefecture 380–8582 Japan (Japan); Nishimura, Hideki [Department of Respiratory Surgery and Breast Surgery, Nagano Municipal Hospital, 1333–1 Tomitake, Nagano City, Nagano Prefecture 381–8551 Japan (Japan); Kusama, Ritsu [Department of Surgery, Hokushin General Hospital, 1-5-63 Nishi, Nakano City, Nagano Prefecture 383–8505 Japan (Japan); Yoshida, Teruhiko [Division of Genetics, National Cancer Center Research Institute, 5-1-1 Tsukiji, Chuo-ku, Tokyo 104–0045 Japan (Japan); Yokoyama, Kazuhito [Department of Epidemiology and Environmental Health, Juntendo University Faculty of Medicine, 2-1-1 Hongo, Bunkyo-ku, Tokyo 113–8421 Japan (Japan); Tsugane, Shoichiro [Dierctor Research Center for Cancer Prevention and Screening, National Cancer Center, 5-1-1 Tsukiji, Chuo-ku, Tokyo 104–0045 Japan (Japan)

2014-08-15

While the global methylation level of leukocyte DNA may be a suitable biomarker for cancer risk, the level may be influenced by multiple factors, both environmental and host-related, one of which is exposure to environmental pollutants. To date, three epidemiologic studies have examined associations between serum organochlorine levels and global DNA methylation level, but their findings are not fully consistent, and the associations thus require confirmation in other well-characterized populations. We tested the association between organochlorine exposure and the global DNA methylation level of leukocytes in Japanese women. We conducted a cross-sectional study using the control group of a breast cancer case–control study in Japan. Subjects were 403 Japanese women who provided blood samples. Serum polychlorinated biphenyls (PCBs) and nine pesticide-related organochlorines were measured by gas chromatography isotope-dilution high-resolution mass spectrometry. Further, global methylation level of peripheral leukocyte DNA among 399 women was measured by luminometric methylation assay. Linear trends in the association between methylation and quartile levels of organochlorines were evaluated by regression coefficients in a multivariable linear regression model. We found significant inverse associations between the global methylation level in leukocyte DNA and many of the organochlorine levels measured. Global methylation level was significantly decreased by 0.33–0.83% per quartile category for serum o,p′-dichlorodiphenyltrichloroethane (o,p′-DDT), p,p′-DDT, p,p′-dichlorodiphenyldichloroethylene, trans-nonachlor, oxychlordane, hexachlorobenzene, β-hexachlorocyclohexane, PCB17, PCB52/69, PCB74, PCB114, and PCB183. Serum organochlorine levels were inversely associated with the global methylation level of leukocyte DNA in a relatively large sample of Japanese women. - Highlights: • Many serum organochlorine pesticides were inversely associated with the global

Criss-cross Cycloadditions on Ketazines Derived from Alicyclic Ketones

Directory of Open Access Journals (Sweden)

Milan Potacek

2006-01-01

Full Text Available The reactivity of alicyclic ketazines in criss-cross cycloadditions was investigated. They react with potassium cyanate and ammonium thiocyanate in the presence of acetic acid to form spirocyclic perhydro[1,2,4]triazolo[1,2-a][1,2,4]triazole-1,5-diones and perhydro[1,2,4]triazolo[1,2-a][1,2,4]triazole-1,5-dithiones, respectively, in relatively high yields.

Aphasia therapy in the age of globalization: cross-linguistic therapy effects in bilingual aphasia.

Science.gov (United States)

Ansaldo, Ana Inés; Saidi, Ladan Ghazi

2014-01-01

Globalization imposes challenges to the field of behavioural neurology, among which is an increase in the prevalence of bilingual aphasia. Thus, aphasiologists have increasingly focused on bilingual aphasia therapy and, more recently, on the identification of the most efficient procedures for triggering language recovery in bilinguals with aphasia. Therapy in both languages is often not available, and, thus, researchers have focused on the transfer of therapy effects from the treated language to the untreated one. This paper discusses the literature on bilingual aphasia therapy, with a focus on cross-linguistic therapy effects from the language in which therapy is provided to the untreated language. Fifteen articles including two systematic reviews, providing details on pre- and posttherapy in the adult bilingual population with poststroke aphasia and anomia are discussed with regard to variables that can influence the presence or absence of cross-linguistic transfer of therapy effects. . The potential for CLT of therapy effects from the treated to the untreated language depends on the word type, the degree of structural overlap between languages, the type of therapy approach, the pre- and postmorbid language proficiency profiles, and the status of the cognitive control circuit.

Globalization in Urology: A Bibliographical Analysis of Cross-Continent Publication between 2002 and 2012.

Science.gov (United States)

Mani, Jens; Juengel, Eva; Bartsch, Georg; Filmann, Natalie; Ackermann, Hanns; Nelson, Karen; Haferkamp, Axel; Engl, Tobias; Blaheta, Roman A

2015-01-01

Asian scientists have now increasingly begun to contribute to globalization; yet it is not clear whether publishing in the field of urology is paralleled by elevated cross-continental scientific publishing. An exemplary bibliometric analysis of urologic journals from 3 different continents was conducted between 2002 and 2012. Based on the ISI Web of Knowledge Journal Citation Reports, 2 urologic journals with similar impact factors (IFs) in 2013 were selected from Europe ('British Journal of Urology International', 'World Journal of Urology'), Asia ('International Journal of Urology', 'Asian Journal of Andrology') and North America ('Urologic Oncology-Seminars and Original Investigations', 'Urology'). The home continent of the journal, the workplace continental affiliation of the last author, article type (clinical, experimental or review) as well as the IF were documented. Most authors published their manuscripts in journals from the same continent in which they worked. However, a significant increase in cross-continental publishing was apparent from 2002 to 2012. Asians publishing in North America increased from 17% in 2002 to 35% in 2012. Europeans also increased the number of articles they published in North American journals, while publications from North American authors were shifted towards both European and Asian journals. Experimental and clinical articles showed significant increases in cross-continental publishing, while review publishing showed no significant change. The average IF for authors from all 3 continents increased from 2002 to 2012 (p < 0.001). The largest increase in the IF was found for Asian authors (0.11 per year). Cross-continental publication significantly increased during the period from 2002 to 2012. The impact that the Asian authors have experienced was found to be gradually impacting the North American and European colleagues. © 2015 S. Karger AG, Basel.

Crossing Digital Bridges for Global Understanding

Science.gov (United States)

Beal, Candy; Bates, Natalie

2010-01-01

The international fantasy world that Walt Disney has developed, and others like it, are designed to create a global community experience for amusement park visitors. Disney's portrayal of many nations--their colorful dress, musical traditions, and unique native cuisine--is many students' only "foreign travel" and the experience may leave them with…

Structure and stabilization of hydrogen-rich transverse.

Energy Technology Data Exchange (ETDEWEB)

Lyra, Sgouria [Sandia National Lab. (SNL-CA), Livermore, CA (United States); Wilde, B [Georgia Inst. of Technology, Atlanta, GA (United States); Kolla, Hemanth [Sandia National Lab. (SNL-CA), Livermore, CA (United States); Seitzman, J. [Georgia Inst. of Technology, Atlanta, GA (United States); Lieuwen, T. C. [Georgia Inst. of Technology, Atlanta, GA (United States); Chen, Jacqueline H. [Sandia National Lab. (SNL-CA), Livermore, CA (United States)

2014-07-01

This paper reports the results of a joint experimental and numerical study of the ow characteristics and flame stabilization of a hydrogen rich jet injected normal to a turbulent, vitiated cross ow of lean methane combustion products. Simultaneous high-speed stereoscopic PIV and OH PLIF measurements were obtained and analyzed alongside three-dimensional direct numerical simulations of inert and reacting JICF with detailed H₂/CO chemistry. Both the experiment and the simulation reveal that, contrary to most previous studies of reacting JICF stabilized in low-to-moderate temperature air cross ow, the present conditions lead to an autoigniting, burner-attached flame that initiates uniformly around the burner edge. Significant asymmetry is observed, however, between the reaction zones located on the windward and leeward sides of the jet, due to the substantially different scalar dissipation rates. The windward reaction zone is much thinner in the near field, while also exhibiting significantly higher local and global heat release than the much broader reaction zone found on the leeward side of the jet. The unsteady dynamics of the windward shear layer, which largely control the important jet/cross flow mixing processes in that region, are explored in order to elucidate the important flow stability implications arising in the reacting JICF. Vorticity spectra extracted from the windward shear layer reveal that the reacting jet is globally unstable and features two high frequency peaks, including a fundamental mode whose Strouhal number of ~0.7 agrees well with previous non-reacting JICF stability studies. The paper concludes with an analysis of the ignition, ame stabilization, and global structure of the burner-attached flame. Chemical explosive mode analysis (CEMA) shows that the entire windward shear layer, and a large region on the leeward side of the jet, are highly explosive prior to ignition and are dominated by non-premixed flame structures after

To share and be shared

DEFF Research Database (Denmark)

Winther, Ida Wentzel

2018-01-01

to another. To a certain degree, they share their everyday lives, things, places, memories, and past/future, but as the ones who move back and forth, they belong a little less in each place. This article is about children who are shared between their parent, households and siblings. They are shared...

Globalization, English Language Teaching and Turkey

Science.gov (United States)

Altan, Mustafa Zülküf

2017-01-01

Globalization as a concept has been used both positively and negatively by many different people and in many different situations. Depending on the point of view, all definitions on globalization state that it has the power of creating a world without boundaries where people communicate, share, and do business with the help of information,…

Optimal Cross-Layer Design for Energy Efficient D2D Sharing Systems

KAUST Repository

Alabbasi, AbdulRahman; Shihada, Basem

2016-01-01

modified energy per good bit (MEPG) metric, with respect to the spectrum sharing user’s transmission power and media access frame length. The cellular users, legacy users, are protected by an outage probability constraint. To optimize the non

Analytic clock frequency selection for global DVFS

NARCIS (Netherlands)

Gerards, Marco Egbertus Theodorus; Hurink, Johann L.; Holzenspies, P.K.F.; Kuper, Jan; Smit, Gerardus Johannes Maria

2014-01-01

Computers can reduce their power consumption by decreasing their speed using Dynamic Voltage and Frequency Scaling (DVFS). A form of DVFS for multicore processors is global DVFS, where the voltage and clock frequency is shared among all processor cores. Because global DVFS is efficient and cheap to

Trends in production-sharing contracts in Nigeria

International Nuclear Information System (INIS)

Ofoh, E.P.

1992-01-01

Nigeria, as a member of the Oil Producing and Exporting Countries (OPEC), today operates various forms of Joint Venture arrangements. From 1908, when oil exploration first began in Nigeria by a German company, the Nigerian Bitumen Corporation (NBC), through 1937 when Shell D'Arcy took concession of the entire country as a single block to 1972 when more than 13 international companies joined the entrepreneurship, the Nigeria Petroleum Industry has witnessed numerous forms of Production Sharing Contract agreements. These arrangements which reflected state of the art of industry at the time, ranged from simply Tax and Royalty only through Equity Sharing to PRODUCTION SHARING AGREEMENTS. In this paper, each phase of these agreements partly reflected the following: Prevailing Fiscal and Economic Environment in the Country. National Development and International Obligations/Needs. State of Global Economy. It discuss among other things: The Economic implications of each arrangement to both Joint Venture partners. The possible future trends and their implications. The salient points in each arrangement shall be highlighted

Preserving the global environment: The challenge of shared leadership

International Nuclear Information System (INIS)

Matthews, J.T.

1993-01-01

This book brings together essays commissioned as background reading for an April 1990 conference on the global environment co-sponsored by the American Assembly and the World Resources Institute. Among the topic areas covered are the following: technical aspects of energy policy and climatic change; harnessing the power of the marketplace; international cooperation; international regulatory regimes; world economic climate; deforestation and species loss; human population growth

Equity implications of two burden-sharing rules for stabilizing greenhouse-gas concentrations

International Nuclear Information System (INIS)

Miketa, Asami; Schrattenholzer, Leo

2006-01-01

This paper focuses on the equity aspects of international burden sharing for global CO 2 emission stabilization. It first summarizes and classifies equity principles proposed in the published literature of the field. Of these, the authors selected three major equity principles, i.e., egalitarian equity, horizontal equity, and proportional equality (often referred to also as sovereign equity) to carry out a detailed examination of two sets of quantitative emission entitlements, which are based on two burden-sharing rules, i.e., the equal emissions per capita approach and the carbon intensity approach. The two burden-sharing rules were chosen as not only particularly popular, but also because their application results in distinctly different burden sharing among countries. To make the two rules comparable, we used a global carbon-emission path until the year 2050 that leads to an atmospheric CO 2 concentration of 550 ppm. We then used the two rules for allocating the global emissions described by that path to allocate carbon emission entitlements to 67 countries and 9 world regions. In general, developing countries receive relatively higher entitlements under the equal emissions per capita approach whereas industrialized countries are relatively better off under the carbon intensity approach. In some countries and regions, emission entitlements as calculated by any of the two burden-sharing rules are so low that it would be unrealistic to assume that actual emissions can be limited to the emission entitlements assigned to them without using flexibility mechanisms such as those defined in the Kyoto Protocol. In this sense, the calculated entitlements can be also interpreted as the initial allocation of tradable emission allowances of countries or regions. Nonetheless, we considered any numerical determination of resulting carbon trade flows to be outside the scope of our paper

Modifiable risk factors for prescription medicine sharing behaviours.

Science.gov (United States)

Beyene, Kebede; Aspden, Trudi; McNeill, Rob; Sheridan, Janie

2018-04-06

Prescription medicine sharing has been defined as giving one's own medicine to someone else (lending) or taking someone else's medicine (borrowing). Medicines can be shared for non-medical purposes (recreational sharing or drug abuse) or for their intended therapeutic benefits (non-recreational sharing, e.g. sharing antibiotics to self-treat); the latter is the focus of this research. Limited research evidence is available about modifiable risk factors for non-recreational medicine sharing and addressing this issue was the main aim of this research. An online, cross-sectional survey design was used. The study population comprised a convenience sample of 233 adults, who were primarily recruited through patient support groups across New Zealand. Principal component analysis was used to develop scales assessing attitudes toward medicine lending and borrowing. Logistic regression was used to examine the relationship between explanatory (demographics, medical conditions, and attitudes towards medicine sharing) and outcome (medicine sharing behaviours) variables. Half of the study participants reported ever borrowing/lending medicines, and approximately a third of participants reported borrowing/lending in the past year. Modifiable risk factors associated with an increased risk of medicine borrowing behaviour were having more difficulty with accessing medicine ('access-related issue'), stronger 'emotional beliefs about borrowing', and greater 'concern about missing doses.' Greater 'concern for the wellbeing of others' and stronger 'beliefs about the benefits and safety of lending' were associated with an increased risk of medicine lending behaviour. Those with a higher 'perceived risk of harm' were less likely to borrow or lend medicines. This research expands the current knowledge of medicine sharing by examining underlying behavioural factors which predict sharing behaviours and that can be modified by interventions. This research suggests using multifaceted

Quantitative imaging of turbulent and reacting flows

Energy Technology Data Exchange (ETDEWEB)

Paul, P.H. [Sandia National Laboratories, Livermore, CA (United States)

1993-12-01

Quantitative digital imaging, using planar laser light scattering techniques is being developed for the analysis of turbulent and reacting flows. Quantitative image data, implying both a direct relation to flowfield variables as well as sufficient signal and spatial dynamic range, can be readily processed to yield two-dimensional distributions of flowfield scalars and in turn two-dimensional images of gradients and turbulence scales. Much of the development of imaging techniques to date has concentrated on understanding the requisite molecular spectroscopy and collision dynamics to be able to determine how flowfield variable information is encoded into the measured signal. From this standpoint the image is seen as a collection of single point measurements. The present effort aims at realizing necessary improvements in signal and spatial dynamic range, signal-to-noise ratio and spatial resolution in the imaging system as well as developing excitation/detection strategies which provide for a quantitative measure of particular flowfield scalars. The standard camera used for the study is an intensified CCD array operated in a conventional video format. The design of the system was based on detailed modeling of signal and image transfer properties of fast UV imaging lenses, image intensifiers and CCD detector arrays. While this system is suitable for direct scalar imaging, derived quantities (e.g. temperature or velocity images) require an exceptionally wide dynamic range imaging detector. To apply these diagnostics to reacting flows also requires a very fast shuttered camera. The authors have developed and successfully tested a new type of gated low-light level detector. This system relies on fast switching of proximity focused image-diode which is direct fiber-optic coupled to a cooled CCD array. Tests on this new detector show significant improvements in detection limit, dynamic range and spatial resolution as compared to microchannel plate intensified arrays.

Unidata: A geoscience e-infrastructure for International Data Sharing

Science.gov (United States)

Ramamurthy, Mohan

2017-04-01

The Internet and its myriad manifestations, including the World Wide Web, have amply demonstrated the compounding benefits of a global cyberinfrastructure and the power of networked communities as institutions and people exchange knowledge, ideas, and resources. The Unidata Program recognizes those benefits, and over the past several years it has developed a growing portfolio of international data distribution activities, conducted in close collaboration with academic, research and operational institutions on several continents, to advance earth system science education and research. The portfolio includes provision of data, tools, support and training as well as outreach activities that bring various stakeholders together to address important issues, all toward the goals of building a community with a shared vision. The overarching goals of Unidata's international data sharing activities include: • democratization of access-to and use-of data that describe the dynamic earth system by facilitating data access to a broad spectrum of observations and forecasts • building capacity and empowering geoscientists and educators worldwide by building encouraging local communities where data, tools, and best practices in education and research are shared • strengthening international science partnerships for exchanging knowledge and expertise • Supporting faculty and students at research and educational institutions in the use of Unidata systems building regional and global communities around specific geoscientific themes. In this presentation, I will present Unidata's ongoing data sharing activities in Latin America, Europe, Africa and Antarctica that are enabling linkages to existing and emergent e-infrastructures and operational networks, including recent advances to develop interoperable data systems, tools, and services that benefit the geosciences. Particular emphasis in the presentation will be made to describe the examples of the use of Unidata

Global Green Governance: Embedding the Green Economy in a Global Green and Equitable Rule of Law Polity

NARCIS (Netherlands)

Gupta, J.; Sanchez, N.

2012-01-01

The global community is crossing planetary boundaries while it has not yet met the basic needs of at least one-third of the global population. Although governance systems are developing, they are still unable to adequately deal with current global environmental problems. This article assesses global

THE INFLUENCE OF HOME COUNTRY MACROECONOMIC FACTORS ON INWARD CROSS-BORDER MERGERS AND ACQUISITIONS: THE CASE OF ROMANIA

Directory of Open Access Journals (Sweden)

Sehleanu Mariana

2015-07-01

Full Text Available Expanding abroad and entering on foreign markets is a natural step in the process of growth and development of firms. Cross-border mergers and acquisitions represent, currently, an important tool in the competitive struggle, which is increasingly intense due to the globalization of economies, and also the driving force behind the growth of Foreign Direct Investments (FDI flows globally. In Romania, the share of cross-border mergers and acquisitions inflows in the total FDI inflows increased progressively, reaching 46,6% in 2006, when the highest value of these transactions was registered (5.308 million dollars, according to UNCTAD. The aim of this empirical research is to study the correlation between the number of inward cross-border mergers acquisitions and a series of other variables, considered factors of influence, over the period 1992-2013. Using simple regression models, the study reveals that economic factors such as Gross domestic product (GDP, stock market capitalization (as a percentage of GDP, interest rate, exchange rate, M2 monetary aggregate and inflation have an important role in explaining cross-border mergers and acquisitions inflows. Between the number of inward cross-border mergers and acquisitions and GDP, M2 monetary aggregate, market capitalization, respectively the exchange rate, there is a direct and linear correlation and between the number of inward mergers and acquisitions and the interest rate, respectively the inflation, there is an inverse linear correlation. The research conducted reveals the important role played by macroeconomic factors with regard to the cross-border mergers and acquisitions inflows, as an entry mode of FDI in Romania.

Implementation methods of medical image sharing for collaborative health care based on IHE XDS-I profile.

Science.gov (United States)

Zhang, Jianguo; Zhang, Kai; Yang, Yuanyuan; Sun, Jianyong; Ling, Tonghui; Wang, Mingqing; Bak, Peter

2015-10-01

IHE XDS-I profile proposes an architecture model for cross-enterprise medical image sharing, but there are only a few clinical implementations reported. Here, we investigate three pilot studies based on the IHE XDS-I profile to see whether we can use this architecture as a foundation for image sharing solutions in a variety of health-care settings. The first pilot study was image sharing for cross-enterprise health care with federated integration, which was implemented in Huadong Hospital and Shanghai Sixth People's Hospital within the Shanghai Shen-Kang Hospital Management Center; the second pilot study was XDS-I-based patient-controlled image sharing solution, which was implemented by the Radiological Society of North America (RSNA) team in the USA; and the third pilot study was collaborative imaging diagnosis with electronic health-care record integration in regional health care, which was implemented in two districts in Shanghai. In order to support these pilot studies, we designed and developed new image access methods, components, and data models such as RAD-69/WADO hybrid image retrieval, RSNA clearinghouse, and extension of metadata definitions in both the submission set and the cross-enterprise document sharing (XDS) registry. We identified several key issues that impact the implementation of XDS-I in practical applications, and conclude that the IHE XDS-I profile is a theoretically good architecture and a useful foundation for medical image sharing solutions across multiple regional health-care providers.

Skin sensitization potency and cross-reactivity of p-phenylenediamine and its derivatives evaluated by non-radioactive murine local lymph node assay and guinea-pig maximization test.

Science.gov (United States)

Yamano, Tetsuo; Shimizu, Mitsuru

2009-04-01

p-Phenylenediamine (PPD)-related chemicals have been used as antioxidants in rubber products, and many cases of contact dermatitis caused by these chemicals have been reported. The aim of this study was to investigate relative sensitizing potency and cross-reactivity among PPD derivatives. Five PPD derivatives, p-aminodiphenylamine (PADPA), N,N'-diphenyl-p-phenylenediamine (DPPD), N-isopropyl-N'-phenyl-p-phenylenediamine (IPPD), N-(1,3-dimethylbutyl)-N'-phenyl-p-phenylenediamine (DMBPPD), N-(1-methylheptyl)-N'-phenyl-p-phenylenediamine (MHPPD), and the core chemical PPD were evaluated for their sensitizing potency and cross-reactivity using the non-radioactive murine local lymph node assay (LLNA) and the guinea-pig maximization test (GPMT). PPD and all the derivatives were identified as primary sensitizers in both tests. The order of potency in the LLNA was as follows: IPPD and PADPA > PPD > DMBPPD and MHPPD > DPPD. In the GPMT, all six groups of animals sensitized with one of these chemicals cross-reacted to four other derivatives. Specifically, the five groups that have a common basic PADPA structure, that is PADPA, DPPD, IPPD, DMBPPD, and MHPPD, all reacted to each other at almost the same scores, while none of them reacted to PPD. The cross-reactivity profile found in the study was to some extent different from that in previous human data, where distinction between cross-reaction and concomitant primary sensitization is not always clear.

‘Sharing the Pie’: Taxing multinationals in a global market

NARCIS (Netherlands)

M.F. de Wilde (Maarten)

2015-01-01

markdownabstract__Abstract__ The current international corporate tax regime for taxing the business proceeds of firms operates arbitrarily. The aggregates of the nation states’ international corporate tax systems seem to distort a global efficient allocation of resources. The current model of

Developing Global Leaders: Building Effective Global- Intercultural Collaborative Online Learning Environments

Science.gov (United States)

Ivy, Karen Lynne-Daniels

2017-01-01

This paper shares the findings of a study conducted on a virtual inter-cultural global leadership development learning project. Mixed Methods analysis techniques were used to examine the interviews of U.S. and Uganda youth project participants. The study, based on cultural and social constructivist learning theories, investigated the effects of…

Full and Open Access to Data in the Global Earth Observing System of Systems (GEOSS): Implementing the GEOSS Data Sharing Principles

Science.gov (United States)

Chen, R. S.; Uhlir, P. F.; Gabrinowicz, J. I.

2008-12-01

Full and open access to data from remote sensing platforms and other sources can facilitate not only scientific research but also the more widespread and effective use of scientific data for the benefit of society. The Global Earth Observing System of Systems (GEOSS) is a major international initiative of the Group on Earth Observations (GEO) to develop "coordinated, comprehensive and sustained Earth observations and information." In 2005, GEO adopted the GEOSS Data Sharing Principles, which call for the "full and open exchange of data, metadata, and products shared within GEOSS, recognizing relevant international instruments and national policies and legislation." These Principles also note that "All shared data, metadata, and products will be made available with minimum time delay and at minimum cost" and that "All shared data, metadata, and products being free of charge or no more than cost of reproduction will be encouraged for research and education." GEOSS Task DA-06-01, aimed at developing a set of recommended implementation guidelines for the Principles, was established in 2006 under the leadership of CODATA, the Committee on Data for Science and Technology of the International Council for Science (ICSU). An international team of authors has developed a draft White Paper on the GEOSS Data Sharing Principles and a proposed set of implementation guidelines. These have been carefully reviewed by independent reviewers, various GEO Committees, and GEO National Members and Participating Organizations. It is expected that the proposed implementation guidelines will be discussed at the GEO-V Plenary in Budapest in November 2008. The current version of the proposed implementation guidelines recognizes the importance of good faith, voluntary adherence to the Principles by GEO National Members and Participating Organizations. It underscores the value of reuse and re-dissemination of GEOSS data with minimum restrictions, not only within GEOSS itself but on the part of

Cross border M and A environment

International Nuclear Information System (INIS)

Hill, M.B.

1998-01-01

An overview of the Canada-U.S. cross-border merger and acquisition environment and exchangeable share structure within the petroleum industry is provided. Recent U.S. acquisitions in Canada, Canadian investment conditions, indexed price analysis from January 1, 1997 to October 16, 1998, and a variety of other share price/cash flow statistics relevant to mergers and acquisitions are examined. tabs., figs

Uber drivers in Cape Town: Working conditions and worker agency in the sharing economy

OpenAIRE

Geitung, Ine

2017-01-01

The effects of the sharing economy on labour have been intensely discussed in recent years. Some are praising the effective, and sustainability implications of the sharing economy. Others are critiquing the deregulation of labour and growth of non-standard labour relations that shift risk from employer to employee. While the discussions have largely taken place in a US or European context, the sharing economy is not limited to the global North. This study examines the working conditions of Ub...

Cloning and characterization of profilin (Pru du 4), a cross-reactive almond (Prunus dulcis) allergen.

Science.gov (United States)

Tawde, Pallavi; Venkatesh, Yeldur P; Wang, Fang; Teuber, Suzanne S; Sathe, Shridhar K; Roux, Kenneth H

2006-10-01

The identity of allergenic almond proteins is incomplete. Our objective was to characterize patient IgE reactivity to a recombinant and corresponding native almond allergen. An almond cDNA library was screened with sera from patients with allergy for IgE binding proteins. Two reactive clones were sequenced, and 1 was expressed. The expressed recombinant allergen and its native counterpart (purified from unprocessed almond flour) were assayed by 1-dimensional and 2-dimensional gel electrophoresis, dot blot, and ELISA, and screened for cross-reactivity with grass profilin. The 2 selected clones encoded profilin (designated Pru du 4) sequences that differed by 2 silent mutations. By dot-blot analyses, 6 of 18 patient sera (33%) reacted with the recombinant Pru du 4 protein, and 8 of 18 (44%) reacted with the native form. ELISA results were similar. Almond and ryegrass profilins were mutually inhibitable. Two-dimensional immunoblotting revealed the presence of more than 1 native almond profilin isoform. The strength of reactivity of some patients' serum IgE differed markedly between assays and between native and recombinant profilins. Almond nut profilin is an IgE-binding food protein that is cross-reactive with grass pollen profilin and is susceptible to denaturation, resulting in variable reactivity between assay types and between patients. Serum IgE of nearly half of the tested patients with almond allergy reacts with almond nut profilin. Because most patients also had pollinosis, the well-known cross-reactivity between pollen and food profilins could account for this pattern of reactivity.

Sharing knowledge

Energy Technology Data Exchange (ETDEWEB)

2009-07-01

The workshop on Climate Change Impacts and Adaptation Strategies for Arctic Indigenous Communities is one stage in developing positions and providing input from the perspectives of Arctic Peoples in preparation for the Indigenous Peoples' Global Summit on Climate Change that will take place in April, 2009, in Anchorage, Alaska. The Summit, organized by the Inuit Circumpolar Council with oversight of an International Steering Committee, will bring together hundreds of indigenous Peoples around the world. This Workshop intended to bring together Arctic Indigenous Peoples to deliver and to share information, academic research, case studies based on traditional knowledge and researchers knowledgeable in traditional knowledge and/or policy issues drawn from traditional knowledge. The following themes were discussed: 1) Traditional knowledge research and education; 2) Laws and lawmaking; 3) Food and health; 4) Organisation; 5) Communications and advocacy. (ln)

Cross-cultural similarities and differences in North Americans' geographic location judgments.

Science.gov (United States)

Friedman, Alinda; Kerkman, Dennis D; Brown, Norman R; Stea, David; Cappello, Hector M

2005-12-01

We examined some potential causes of bias in geographic location estimates by comparing location estimates of North American cities made by Canadian, U.S., and Mexican university students. All three groups placed most Mexican cities near the equator, which implies that all three groups were influenced by shared beliefs about the locations of geographical regions relative to global reference points. However, the groups divided North America into different regions and differed in the relative accuracy of the estimates within them, which implies that there was an influence of culture-specific knowledge. The data support a category-based system of plausible reasoning, in which biases in judgments are multiply determined, and underscore the utility of the estimation paradigm as a tool in cross-cultural cognitive research.

The cross-country implications of alternative climate policies

International Nuclear Information System (INIS)

Li, Aijun; Du, Nan; Wei, Qian

2014-01-01

Because of worldwide growing concerns about global climate change, great interest has been expressed in the potential of alternative climate policies to reduce global carbon emissions. In this paper, we compare cross-country implications of alternative climate policies, including unilateral and multilateral climate policies. Our main findings are as follows. Firstly, there are large differences in cross-country effects of alternative unilateral climate policies, when the same given carbon emission reductions are achieved in each abating country respectively. Meanwhile, cross-border externalities undermine efficiency of unilateral climate policies. Secondly, there are significant differences in cross-country implications of alternative multilateral climate policies, when the same global emission reductions are allocated in several different ways among abating countries. Thirdly, it is difficult to reach a stable global climate treaty, since any abating country has the incentive to argue for small carbon emission reductions. Finally, multilateral climate policies can reduce the negative impacts of cross-border externalities, but cannot cure all cross-border externalities. Looking ahead, it will be a great policy challenge for the world to reduce carbon emissions in a cost-effective way. - highlights: • We compare impacts of unilateral climate policies across countries. • We compare effects of alternative multilateral climate policies. • We explore whether cross-border externalities disappear under multilateral climate policies

Globalization and Contemporary Fertility Convergence.

Science.gov (United States)

Hendi, Arun S

2017-09-01

The rise of the global network of nation-states has precipitated social transformations throughout the world. This article examines the role of political and economic globalization in driving fertility convergence across countries between 1965 and 2009. While past research has typically conceptualized fertility change as a country-level process, this study instead employs a theoretical and methodological framework that examines differences in fertility between pairs of countries over time. Convergence in fertility between pairs of countries is hypothesized to result from increased cross-country connectedness and cross-national transmission of fertility-related schemas. I investigate the impact of various cross-country ties, including ties through bilateral trade, intergovernmental organizations, and regional trade blocs, on fertility convergence. I find that globalization acts as a form of social interaction to produce fertility convergence. There is significant heterogeneity in the effects of different cross-country ties. In particular, trade with rich model countries, joint participation in the UN and UNESCO, and joining a free trade agreement all contribute to fertility convergence between countries. Whereas the prevailing focus in fertility research has been on factors producing fertility declines, this analysis highlights specific mechanisms-trade and connectedness through organizations-leading to greater similarity in fertility across countries. Globalization is a process that propels the spread of culturally laden goods and schemas impinging on fertility, which in turn produces fertility convergence.

Is There Rent Sharing in Italy? Evidence from Employer-Employee Data

Directory of Open Access Journals (Sweden)

Alessia Matano

2011-12-01

Full Text Available Using a unique employer-employee panel database, we investigate the extent of rent sharing in Italy from 1996 to 2003. We derive the following findings. First, after controlling for the national bargaining level, there is robust evidence of rent sharing at firm level. Second, by means of fixed effects estimates we show that the sorting of high-ability workers into high-profit firms appears to play a substantial role, since it captures a significant amount of cross sectional estimates of rent sharing. Third, in accordance to the related literature the endogeneity of profits causes a severe underestimation of rent sharing. Our final IV estimate of the elasticity of wages with respect to profits per employee amounts to 6%, with a "Lester" range of 24%. Moreover, we point out that the impact of rent sharing is not homogeneous across several dimensions (gender, occupation, sector and macroarea.

Cross-reactivity of human nickel-reactive T-lymphocyte clones with copper and palladium

NARCIS (Netherlands)

Pistoor, F. H.; Kapsenberg, M. L.; Bos, J. D.; Meinardi, M. M.; von Blomberg, M. E.; Scheper, R. J.

1995-01-01

Twenty Ni-reactive T-lymphocyte clones were obtained from eight different donors and analyzed for their ability to cross-react with other metals. All Ni-reactive T-lymphocyte clones were CD4+CD8- and recognized Ni in association with either HLA-DR or -DQ molecules. Based on the periodic table of the

Extensive CD4 and CD8 T Cell cross-reactivity between alphaherpesviruses

DEFF Research Database (Denmark)

Jing, Lichen; Laing, Kerry J.; Dong, Lichun

2016-01-01

The Alphaherpesvirinae subfamily includes HSV types 1 and 2 and the sequence-divergent pathogen varicella zoster virus (VZV). T cells, controlled by TCR and HLA molecules that tolerate limited epitope amino acid variation, might cross-react between these microbes. We show that memory PBMC expansi...... be useful for multi-alphaherpesvirus vaccine design and adoptive cellular therapy....

Numerical Simulations of Two-Phase Reacting Flow in a Single-Element Lean Direct Injection (LDI) Combustor Using NCC

Science.gov (United States)

Liu, Nan-Suey; Shih, Tsan-Hsing; Wey, C. Thomas

2011-01-01

A series of numerical simulations of Jet-A spray reacting flow in a single-element lean direct injection (LDI) combustor have been conducted by using the National Combustion Code (NCC). The simulations have been carried out using the time filtered Navier-Stokes (TFNS) approach ranging from the steady Reynolds-averaged Navier-Stokes (RANS), unsteady RANS (URANS), to the dynamic flow structure simulation (DFS). The sub-grid model employed for turbulent mixing and combustion includes the well-mixed model, the linear eddy mixing (LEM) model, and the filtered mass density function (FDF/PDF) model. The starting condition of the injected liquid spray is specified via empirical droplet size correlation, and a five-species single-step global reduced mechanism is employed for fuel chemistry. All the calculations use the same grid whose resolution is of the RANS type. Comparisons of results from various models are presented.

The Rhetoric of Culture as an Act of Closure in a Cross-National Software Development Department

DEFF Research Database (Denmark)

Jensen, Rasmus Eskild; Nardi, Bonnie

2014-01-01

Global software teams work on interdependent tasks across geographies, time zones, and cultures. Studies of cross-national software teams report that the main challenges are sharing knowledge, creating trust, and establishing common ground. In this study we examine another challenge—the use...... of the word “culture” as an exclusionary act of closure. As theorized by Metiu, who builds on Weber, closure occurs when one group seeks to preserve the advantages of their situation relative to another group. We conducted an ethnographic study of a cross-national software department with members in Denmark...... and the Philippines. We found that “culture” was invoked by employees in the Danish office to explain failed collaborations, but not by employees in the Philippines. Filipino employees formulated other explanations for problems, and actively resisted cultural explanations. We argue that employees in the Danish office...

The Resilience of Dependency Effects in Explaining Income Inequality in the Global Economy: A Cross National Analysis, 1975-1995

Directory of Open Access Journals (Sweden)

Linda Beer

2015-08-01

Full Text Available The contemporary era is one of both accelerated economic globalization and rising inequality. There is an increasing awareness among both academic scholars and development professionals that globalization puts certain populations at risk. However, there has been inadequate theoretical analysis and a lack of up to date empirical studies that explain just how contemporary globalization a?ects inequality and the well being of individuals. This study explores the conditions under which TNC penetration and other globalization processes in?uence change in domestic income distribution. Its aim is to investigate whether theoretical models that have proven successful in explaining di?erences in income inequality cross-sectionally also allow for an understanding of the dynamics of income distribution during the 1980s and early 1990s, an era characterized by a dramatic acceleration of globalization. We present an analysis of change in national income distribution using linear regression models with a panel design. This study suggests that dependence on foreign investment as a development strategy, especially compared to domestic and human capital investment, may be misguided for nations concerned with equality. Net of other factors, foreign investment dependence bene?ts the elite segments of the income-earning population over the poorer eighty percent. Our analysis provides evidence of a shift in capital/labor relations brought about by globalization that has signi? cantly contributed to the rise in income inequality seen throughout the world.

Multiphase reacting flows modelling and simulation

CERN Document Server

Marchisio, Daniele L

2007-01-01

The papers in this book describe the most widely applicable modeling approaches and are organized in six groups covering from fundamentals to relevant applications. In the first part, some fundamentals of multiphase turbulent reacting flows are covered. In particular the introduction focuses on basic notions of turbulence theory in single-phase and multi-phase systems as well as on the interaction between turbulence and chemistry. In the second part, models for the physical and chemical processes involved are discussed. Among other things, particular emphasis is given to turbulence modeling strategies for multiphase flows based on the kinetic theory for granular flows. Next, the different numerical methods based on Lagrangian and/or Eulerian schemes are presented. In particular the most popular numerical approaches of computational fluid dynamics codes are described (i.e., Direct Numerical Simulation, Large Eddy Simulation, and Reynolds-Averaged Navier-Stokes approach). The book will cover particle-based meth...

Preparing Globally Competent Teacher Candidates through Cross-Cultural Experiential Learning

Science.gov (United States)

Kopish, Michael A.

2016-01-01

This manuscript presents findings and implications from a case study of one global educator's attempt to develop globally competent teacher candidates in an elective teacher preparation course. Global Citizenship Education served as the framing paradigm for the course and human experiences of immigrants and refugees served as the milieu for…

How Does Culture Matter in the Face of Globalization?

Science.gov (United States)

Hong, Ying-Yi; Cheon, Bobby K

2017-09-01

Globalization has made exposure to multiple cultures not only possible, but often necessary and unavoidable. This article focuses on how people react and adapt to increasing globalization and multiculturalism. We posit that reactions to multiculturalism and intercultural contact are not universal and are themselves shaped by cultural experiences. That is, culture provides a frame of reference for reconciling and negotiating the inflow of foreign cultures and peoples. Although exposure to foreign cultures can widen one's worldview, thereby enhancing creativity and reducing prejudice, intercultural contact can also bring about negative exclusionary responses such as aversion, disgust, and defensiveness. We explore how culture and individual differences, such as a belief in racial essentialism, critically shape reactions to intercultural contact. Our discussion sheds light on recent geopolitical and societal shifts that reflect an increased backlash against rising globalization and cultural diversity.

Analysis of the trend to equilibrium of a chemically reacting system

International Nuclear Information System (INIS)

Kremer, Gilberto M; Bianchi, Miriam Pandolfi; Soares, Ana Jacinta

2007-01-01

In this present paper, a quaternary gaseous reactive mixture, for which the chemical reaction is close to its final stage and the elastic and reactive frequencies are comparable, is modelled within the Boltzmann equation extended to reacting gases. The main objective is a detailed analysis of the non-equilibrium effects arising in the reactive system A 1 + A 2 ↔ A 3 + A 4 , in a flow regime which is considered not far away from thermal, mechanical and chemical equilibrium. A first-order perturbation solution technique is applied to the macroscopic field equations for the spatially homogeneous gas system, and the trend to equilibrium is studied in detail. Adopting elastic hard-spheres and reactive line-of-centres cross sections and an appropriate choice of the input distribution functions-which allows us to distinguish the two cases where the constituents are either at same or different temperatures-explicit computations of the linearized production terms for mass, momentum and total energy are performed for each gas species. The departures from the equilibrium states of densities, temperatures and diffusion fluxes are characterized by small perturbations of their corresponding equilibrium values. For the hydrogen-chlorine system, the perturbations are plotted as functions of time for both cases where the species are either at the same or different temperatures. Moreover, the trend to equilibrium of the reaction rates is represented for the forward and backward reaction H 2 + Cl ↔ HCl + H

High altitude environmental monitoring: the SHARE project and CEOP-HE

Science.gov (United States)

Tartari, G.

2009-04-01

Mountain areas above 2,500 m a.s.l. constitute about 25% of the Earth's surface and play a fundamental role in the global water balance, while influencing global climate and atmospheric circulation systems. Several millions, including lowlanders, are directly affected by the impacts of climate change on glaciers and water resource distribution. Mountains and high altitude plateaus are subject to the highest rate of temperature increase (e.g., Tibetan Plateau) and are recognized as particularly vulnerable to the effects of climate change. In spite of this, the number of permanent monitoring sites in the major environmental networks decreases with altitude. On a sample of two hundred high altitude automatic weather stations located above 2,500 m a.s.l., less than 20% are over 4,000 m, while there are only 24 stations in the world that could be considered "complete" high altitude observatories. Furthermore, entire mountain areas are left uncovered, creating significant data gaps which make reliable modelling and forecasting nearly impossible. In response to these problems, Ev-K2-CNR has developed the project SHARE (Stations at High Altitude for Research on the Environment) with the support of the Italian government and in collaboration with UNEP. This integrated environmental monitoring and research project aims to improve knowledge on the local, regional and global consequences of climate change in mountain regions and on the influence of high elevations on climate, atmospheric circulation and hydrology. SHARE today boasts a network of 13 permanent monitoring stations between 2,165 m and 8,000 m. Affiliated researchers have produced over 150 scientific publications in atmospheric sciences, meteorology and climate, glaciology, limnology and paleolimnology and geophysics. SHARE network data is also contributed to international programs (UNEP-ABC, WMO-GAW, WCRP-GEWEX-CEOP, NASA-AERONET, ILTER, EU-EUSAAR, EU-ACCENT). Within this context, the CEOP-High Elevations (CEOP

Non-equilibrium reacting gas flows kinetic theory of transport and relaxation processes

CERN Document Server

Nagnibeda, Ekaterina; Nagnibeda, Ekaterina

2009-01-01

This volume develops the kinetic theory of transport phenomena and relaxation processes in the flows of reacting gas mixtures. The theory is applied to the modeling of non-equilibrium flows behind strong shock waves, in the boundary layer, and in nozzles.

Global health partnership for student peer-to-peer psychiatry e-learning: Lessons learned.

Science.gov (United States)

Keynejad, Roxanne C

2016-12-03

Global 'twinning' relationships between healthcare organizations and institutions in low and high-resource settings have created growing opportunities for e-health partnerships which capitalize upon expanding information technology resources worldwide. E-learning approaches to medical education are increasingly popular but remain under-investigated, whilst a new emphasis on global health teaching has coincided with university budget cuts in many high income countries. King's Somaliland Partnership (KSP) is a paired institutional partnership health link, supported by Tropical Health and Education Trust (THET), which works to strengthen the healthcare system and improve access to care through mutual exchange of skills, knowledge and experience between Somaliland and King's Health Partners, UK. Aqoon, meaning knowledge in Somali, is a peer-to-peer global mental health e-learning partnership between medical students at King's College London (KCL) and Hargeisa and Amoud Universities, Somaliland. It aims to extend the benefits of KSP's cross-cultural and global mental health education work to medical students and has reported positive results, including improved attitudes towards psychiatry in Somaliland students. The process of devising, piloting, evaluating, refining, implementing, re-evaluating and again refining the Aqoon model has identified important barriers to successful partnership. This article describes lessons learned during this process, sharing principles and recommendations for readers wishing to expand their own global health link beyond qualified clinicians, to the healthcare professionals of the future.

Sharing data under the 21st Century Cures Act.

Science.gov (United States)

Majumder, Mary A; Guerrini, Christi J; Bollinger, Juli M; Cook-Deegan, Robert; McGuire, Amy L

2017-12-01

On 13 December 2016, President Obama signed the 21st Century Cures Act ("the Act") into law. Many of its provisions support the creation of an "Information Commons," an ecosystem of separate but interconnected initiatives that facilitate open and responsible sharing of genomic and other data for research and clinical purposes. For example, the Act supports the National Institutes of Health in mandating data sharing, provides funding and guidance for the large national cohort program now known as All of Us, expresses congressional support for a global pediatric study network, and strengthens patient access to health information. The Act also addresses potential barriers to data sharing. For example, it makes the issuance of certificates of confidentiality automatic for federally funded research involving "identifiable, sensitive" information and strengthens the associated protections. At the same time, the Act exacerbates or neglects several challenges, for example, increasing complexity by adding a new definition of "identifiable" and failing to address the financial sustainability of data sharing and the scope of commercialization. In sum, the Act is a positive step, yet there is still much work to be done before the goals of broad data sharing and utilization can be achieved.

'REACTS'. A pragmatic approach for providing medical care and physician education for radiation emergencies

International Nuclear Information System (INIS)

Lushbaugh, C.C.; Andrews, G.A.; Huebner, K.F.; Cloutier, R.J.; Beck, W.L.; Berger, J.D.

1976-01-01

Because serious radiation incidents have been rare, few medical personnel (notably only some in France, Russia, Belgium, Canada, Yugoslavia, Japan, Great Britain and the United States) have first-hand experience in radiation-accident management. The generation of physicians who participated in those accidents now needs to pass on the bits of knowledge that were gleaned from them. These case histories are difficult for the local, non-radiology physician to obtain when he is called upon to help formulate the medical-emergency response plan required everywhere for licensing power reactors. The Radiation Emergency Assistance Center and Training Site (REACTS) in Oak Ridge, Tennessee, supported by the US Energy Research and Development Administration, is designed to meet these medical and educational needs. REACTS, located in the Oak Ridge Hospital of the Methodist Church, is not involved in the hospital's daily community functions except insofar as REACTS is the radiation emergency arm of the area's major disaster plan. Its dual mission is training physicians, nurses, and paramedical emergency personnel in radiation-accident management, and treating irradiated and contaminated persons. Its training activities are carried out by the Special Training Division of Oak Ridge Associated Universities. Formal courses in radiation medicine and health physics and practical laboratory experience are now conducted twice a year for physicians. They will be expanded in the future to include training of paramedical personnel. Follow-up studies of radiation-accident survivors are carried out in REACTS to ensure the preservation of valuable human data and radiation-accident experiences. This unique facility and its staff are dedicated to meet the needs of the far-flung public and private medical domains in the United States for nuclear-production energy

Tax havens under international pressure: How do they react?

OpenAIRE

Patrice Pieretti; Giuseppe Pulina

2015-01-01

This paper contributes to the literature about tax havens by providing a more comprehensive analysis of their role. The aim is to analyze how low-tax jurisdictions can react to growing international pressure exerted, by high-tax countries, to enforce compliance with anti aggressive tax planning standards. To this end, we model how a small tax haven tries to be attractive to multinationals located in a high-tax region by providing aggressive tax planning services and/or a favorable environment...

Teach for All: Storytelling "Shared Solutions" and Scaling Global Reform

Science.gov (United States)

Ahmann, Chloe

2015-01-01

"Teach For All" is a global network of state-based organizations that translate "Teach For America's" market model of school reform into moral projects of nation-building abroad. Referring to this challenge as one of "scaling" the organization, its leaders elaborate a theory of change that hinges on replicability: in…

Global scientific research commons under the Nagoya Protocol: Towards a collaborative economy model for the sharing of basic research assets.

Science.gov (United States)

Dedeurwaerdere, Tom; Melindi-Ghidi, Paolo; Broggiato, Arianna

2016-01-01

This paper aims to get a better understanding of the motivational and transaction cost features of building global scientific research commons, with a view to contributing to the debate on the design of appropriate policy measures under the recently adopted Nagoya Protocol. For this purpose, the paper analyses the results of a world-wide survey of managers and users of microbial culture collections, which focused on the role of social and internalized motivations, organizational networks and external incentives in promoting the public availability of upstream research assets. Overall, the study confirms the hypotheses of the social production model of information and shareable goods, but it also shows the need to complete this model. For the sharing of materials, the underlying collaborative economy in excess capacity plays a key role in addition to the social production, while for data, competitive pressures amongst scientists tend to play a bigger role.

Combining local and global optimisation for virtual camera control

OpenAIRE

Burelli, Paolo; Yannakakis, Georgios N.; 2010 IEEE Symposium on Computational Intelligence and Games

2010-01-01

Controlling a virtual camera in 3D computer games is a complex task. The camera is required to react to dynamically changing environments and produce high quality visual results and smooth animations. This paper proposes an approach that combines local and global search to solve the virtual camera control problem. The automatic camera control problem is described and it is decomposed into sub-problems; then a hierarchical architecture that solves each sub-problem using the most appropriate op...

Stages in the economic globalization of tourism

DEFF Research Database (Denmark)

Hjalager, Anne Mette

2007-01-01

globalizing process. Outsourcing, transnational ownership structures and investments, cross-border marketing collaborations, the purchase and sale of knowhow, and the free movement of labor are developments not confined to manufacturing alone, but are also highly relevant for the modernization of tourism......There is more to the globalization of tourism than cross-border flows of customers and purchasing power. This paper distinguishes four stages and different manifestations of the globalization of the tourism industry, and shows that it, like many other business systems, is undergoing an irrevocable...

Cross-contamination of foods and implications for food allergic patients.

Science.gov (United States)

Taylor, Steve L; Baumert, Joseph L

2010-07-01

Cross-contamination presents a risk of unknown magnitude for food allergic consumers. Published cases likely represent the tip of a rather large iceberg. Cross-contamination can occur in homes, restaurants, food manufacturing plants, and on farms. The frequency of cross-contamination as the cause of accidental exposures to allergenic foods is unknown. Food allergic individuals can react to ingestion of trace levels of the offending food, although a highly variable range of threshold doses exist among populations of food allergic individuals. The magnitude of the risk posed to food allergic consumers by cross-contamination is characterized by the frequency of exposure to cross-contaminated foods, the dose of exposure, and the individual's threshold dose. The food and food service industry (and food preparers in homes as well) have the responsibility to provide and prepare foods that are safe for food allergic consumers, but quality of life may be improved with the recognition that safe (though very low) thresholds do exist.

THE STABILITY OF OPTICALLY THIN REACTING PLASMAS: EFFECTS OF THE BULK VISCOSITY

International Nuclear Information System (INIS)

Ibanez S, Miguel H.

2009-01-01

The thermochemical stability of reacting plasmas is analyzed by taking into account the change in the thermodynamical equilibrium values during the fluctuation. This shift in the equilibrium produces two main effects: a change in the four instability criteria for reacting gases resulting when the above effect is neglected and adds a fifth instability criterion due to the fact that the corresponding secular equation becomes a fifth-order polynomial. The above results are applied to several plasma models, in particular, to a photoionized hydrogen plasma for which the bulk viscosity can be more important than the dynamic viscosity and the thermometric conductivity. Therefore, the bulk viscosity may quench thermochemical instabilities were the thermal conduction is unable of stabilizing. This occurs for low values of the photoionizing energy E. The implications of the above results in explaining the formation of clump structures in different regions of the interstellar medium are outlined.

Sharing information among existing data sources

Science.gov (United States)

Ashley, W. R., III

1999-01-01

The sharing of information between law enforcement agencies is a premise for the success of all jurisdictions. A wealth of information resides in both the databases and infrastructures of local, state, and regional agencies. However, this information is often not available to the law enforcement professionals who require it. When the information is, available, individual investigators must not only know that it exists, but where it resides, and how to retrieve it. In many cases, these types of cross-jurisdictional communications are limited to personal relationships that result from telephone calls, faxes, and in some cases, e-mail. As criminal elements become more sophisticated and distributed, law enforcement agencies must begin to develop infrastructures and common sharing mechanisms that address a constantly evolving criminal threat. Historically, criminals have taken advantage of the lack of communication between law enforcement agencies. Examples of this are evident in the search for stolen property and monetary dealings. Pawned property, cash transactions, and failure to supply child support are three common cross- jurisdictional crimes that could be better enforced by strengthening the lines of communication. Criminal behavior demonstrates that it is easier to profit from their actions by dealing in separate jurisdictions. For example, stolen property is sold outside of the jurisdiction of its origin. In most cases, simply traveling a short distance to the adjoining county or municipality is sufficient to ensure that apprehension of the criminal or seizure of the stolen property is highly unlikely. In addition to the traditional burglar, fugitives often sell or pawn property to finance their continued evasion from the law. Sharing of information in a rapid manner would increase the ability of law enforcement personnel to track and capture fugitives, as well as criminals. In an example to combat this threat, the State of Florida recently acted on the need to

Managing healthcare services in the global marketplace.

Science.gov (United States)

Fried, Bruce J; Harris, Dean M

2007-01-01

The world is getting "flatter"; people, information, technology, and ideas are increasingly crossing national borders. U.S. healthcare is not immune from the forces of globalization. Competition from medical tourism and the rapid growth in the number of undocumented aliens requiring care represent just two challenges healthcare organizations face. An international workforce requires leaders to confront the legal, financial, and ethical implications of using foreign-trained personnel. Cross-border institutional arrangements are emerging, drawing players motivated by social responsibility, globalization of competitors, growth opportunities, or an awareness of vulnerability to the forces of globalization. Forward-thinking healthcare leaders will begin to identify global strategies that address global pressures, explore the opportunities, and take practical steps to prepare for a flatter world.

Globalization of Management Education

Science.gov (United States)

Bruner, Robert F.; Iannarelli, Juliane

2011-01-01

A new study, sponsored by the Association to Advance Collegiate Schools of Business, presented a comprehensive new perspective on the globalization of management education, (AACSB International, 2011). Its findings are sobering: with regard to emerging global trends in higher education and cross-border business, the report reveals a sizable gap…

Public and Biobank Participant Attitudes toward Genetic Research Participation and Data Sharing

OpenAIRE

Lemke, A.A.; Wolf, W.A.; Hebert-Beirne, J.; Smith, M.E.

2010-01-01

Research assessing attitudes toward consent processes for high-throughput genomic-wide technologies and widespread sharing of data is limited. In order to develop a better understanding of stakeholder views toward these issues, this cross-sectional study assessed public and biorepository participant attitudes toward research participation and sharing of genetic research data. Forty-nine individuals participated in 6 focus groups; 28 in 3 public focus groups and 21 in 3 NUgene biorepository pa...

Globalization and Dual Modes of Higher Education Policymaking in France: Je T'aime Moi Non Plus. Research & Occasional Paper Series: CSHE.2.11

Science.gov (United States)

Hoareau, Cecile

2011-01-01

The French Government has had a paradoxical relationship with globalization. Globalization is perceived as both a threat to react against and a cradle for new policy ideas. French policymakers have a love-hate relationship with the European higher education reforms that started in the 1990s, a mixed sentiment that French singer Serge Gainsbourg…

Materials study for reacting plasma machine

International Nuclear Information System (INIS)

Kamada, Kohji; Hamada, Yasuji

1982-01-01

A new reacting plasma machine is designed, and will be constructed at the Institute of Plasma Physics, Nagoya University. It is important to avoid the activation of the materials for the machine, accordingly, aluminum alloy has been considered as the material since the induced activity of aluminum due to 14 MeV neutrons is small. The vacuum chamber of the new machine consists of four modules, and the remote control of each module is considered. However, the cost of the remote control of modules is expensive. To minimize the dependence on the remote control, the use of aluminum alloy is considered as the first step. The low electrical resistivity, over-ageing, weak mechanical strength and eddy current characteristics of aluminum alloy must be improved. The physical and electrical properties of various aluminum alloys have been investigated. Permeability of hydrogen through aluminum, the recycling characteristics and surface coating materials have been also studied. (Kato, T.)

Global bioethics: utopia or reality?

Science.gov (United States)

Hellsten, Sirkku K

2008-08-01

This article discusses what 'global bioethics' means today and what features make bioethical research 'global'. The article provides a historical view of the development of the field of 'bioethics', from medical ethics to the wider study of bioethics in a global context. It critically examines the particular problems that 'global bioethics' research faces across cultural and political borders and suggests some solutions on how to move towards a more balanced and culturally less biased dialogue in the issues of bioethics. The main thesis is that we need to bring global and local aspects closer together when looking for international guidelines, by paying more attention to particular cultures and local economic and social circumstances in reaching a shared understanding of the main values and principles of bioethics, and in building 'biodemocracy'.

Thermal properties of wood reacted with a phosphorus pentoxide–amine system

Science.gov (United States)

Hong-Lin Lee; George C. Chen; Roger M. Rowell

2004-01-01

The objective of this research was to improve the fire-retardant properties of wood in one treatment using a phosphorus pentoxide–amine system. Phosphorus pentoxide and 16 amines including alkyl, halophenyl, and phenyl amines were compounded in N,N-dimethylformamide and the resulting solutions containing phosphoramides were reacted with wood. The characteristics of...

Globalizing Lessons Learned from Regional-scale Observatories

Science.gov (United States)

Glenn, S. M.

2016-02-01

The Mid Atlantic Regional Association Coastal Ocean Observing System (MARACOOS) has accumulated a decade of experience designing, building and operating a Regional Coastal Ocean Observing System for the U.S. Integrated Ocean Observing System (IOOS). MARACOOS serves societal goals and supports scientific discovery at the scale of a Large Marine Ecosystem (LME). Societal themes include maritime safety, ecosystem decision support, coastal inundation, water quality and offshore energy. Scientific results that feed back on societal goals with better products include improved understanding of seasonal transport pathways and their impact on phytoplankton blooms and hypoxia, seasonal evolution of the subsurface Mid Atlantic Cold Pool and its impact on fisheries, biogeochemical transformations in coastal plumes, coastal ocean evolution and impact on hurricane intensities, and storm sediment transport pathways. As the global ocean observing requirements grow to support additional societal needs for information on fisheries and aquaculture, ocean acidification and deoxygenation, water quality and offshore development, global observing will necessarily evolve to include more coastal observations and forecast models at the scale of the world's many LMEs. Here we describe our efforts to share lessons learned between the observatory operators at the regional-scale of the LMEs. Current collaborators are spread across Europe, and also include Korea, Indonesia, Australia, Brazil and South Africa. Specific examples include the development of a world standard QA/QC approach for HF Radar data that will foster the sharing of data between countries, basin-scale underwater glider missions between internationally-distributed glider ports to developed a shared understanding of operations and an ongoing evaluation of the global ocean models in which the regional models for the LME will be nested, and joint training programs to develop the distributed teams of scientists and technicians

Generalized Load Sharing for Homogeneous Networks of Distributed Environment

Directory of Open Access Journals (Sweden)

A. Satheesh

2008-01-01

Full Text Available We propose a method for job migration policies by considering effective usage of global memory in addition to CPU load sharing in distributed systems. When a node is identified for lacking sufficient memory space to serve jobs, one or more jobs of the node will be migrated to remote nodes with low memory allocations. If the memory space is sufficiently large, the jobs will be scheduled by a CPU-based load sharing policy. Following the principle of sharing both CPU and memory resources, we present several load sharing alternatives. Our objective is to reduce the number of page faults caused by unbalanced memory allocations for jobs among distributed nodes, so that overall performance of a distributed system can be significantly improved. We have conducted trace-driven simulations to compare CPU-based load sharing policies with our policies. We show that our load sharing policies not only improve performance of memory bound jobs, but also maintain the same load sharing quality as the CPU-based policies for CPU-bound jobs. Regarding remote execution and preemptive migration strategies, our experiments indicate that a strategy selection in load sharing is dependent on the amount of memory demand of jobs, remote execution is more effective for memory-bound jobs, and preemptive migration is more effective for CPU-bound jobs. Our CPU-memory-based policy using either high performance or high throughput approach and using the remote execution strategy performs the best for both CPU-bound and memory-bound job in homogeneous networks of distributed environment.

A Field Study of Structures, Affordances, and Coordination Mechanisms of a Cross-Organizational Extended Team in Global Software Development

DEFF Research Database (Denmark)

Zahedi, Mansooreh; Ali Babar, Muhammad

Context: Growing popularity of Global Software Development (GSD) has resulted in an increasing number of cross-organizational teams that are formed according to Extended Team Model (ETM). There is little empirical body of knowledge about the structures (work, social, and communication) that may...... exist in these types of teams and the potential strengths and weaknesses of these structures in dealing with GSD challenges. Objective: This research has been motivated by the need of studying the types of work, communication and social structures designed and implemented for a cross...... interviews with both onshore and offshore team members. We applied qualitative data analysis approach called thematic analysis for finding the answers to our key research questions. Results: Our study has identified that the current work structure of ETM create several kinds of interdependencies for which...

ReACT Methodology Proof of Concept Final Report

Energy Technology Data Exchange (ETDEWEB)

Bri Rolston; Sarah Freeman

2014-03-01

The Department of Energy’s Office of Electricity Delivery and Energy Reliability (DOE-OE) funded INL Researchers to evaluate a novel process for assessing and mitigating cyber security risks. The proof of concept level of the method was tested in an industry environment. This case study, plus additional case studies will support the further development of the method into a tool to assist industry in securing their critical networks. This report provides an understanding of the process developed in the Response Analysis and Characterization Tool (ReACT) project. This report concludes with lessons learned and a roadmap for final development of these tools for use by industry.

Flame Structure of Vitiated Fuel-Rich Inverse Diffusion Flames in a Cross-Flow (Postprint)

Science.gov (United States)

2011-12-01

downstream of the slot. The flame length increases as the blowing ratio increases as a result of the greater mass of air which reacts. Ignition of...attributed to the greater penetration of the jet into the cross-stream. It is noted that the flame lengths are similar for the different blowing ratios

Chinese version of the Global Youth Tobacco Survey: cross-cultural instrument adaptation

Directory of Open Access Journals (Sweden)

Chiou Hung-Yi

2008-04-01

Full Text Available Abstract Background Tobacco smoking poses public health concerns because of its high risk for many chronic diseases. Most smokers begin using tobacco in their teens and recent reports indicate that smoking prevalence is climbing among youth. The Global Youth Tobacco Survey (GYTS is a worldwide, school-based, tobacco-specific survey, but cross-cultural differences limit its effectiveness in international studies. Specifically, the GYTS assesses not only the prevalence of smoking, but also tobacco-related attitudes, school curricula, and advertisements, which are culturally influenced. Therefore, we conducted this study to develop a Chinese version of the GYTS for both national surveillance and international comparison. Methods The original English GYTS was translated and back translated using a cross-cultural adaptation process. The comprehensiveness and feasibility of using the Chinese-version GYTS were reviewed by a panel of 6 tobacco-control experts. The understandability and cultural relevance of the Chinese-version GYTS were discussed in a focus group of 5 schoolteachers and 8 students. The expert and focus group feedback was incorporated into a final Chinese version of the GYTS, which was administered to 382 students throughout Taiwan by multi-stage sampling from 10 randomly selected schools. Results The internal consistency (Cronbach's alpha for the GYTS subscales (smoking susceptibility, attitude toward smoking, and media messages about smoking ranged from 0.70 to 0.94. The internal logical agreement of responses ranged from 85.3 to 99.2%. Conclusion The Chinese version of the GYTS has good reliability and validity and can serve as the foundation for international comparison and tobacco control in Chinese-speaking communities.

Concentration and Competition in the Global Meat Market

Directory of Open Access Journals (Sweden)

Bocharova Yuliia G.

2016-03-01

Full Text Available The article is aimed at analyzing the condition, development specifics, concentration and competition in the global meat market. Both significance and role of meat in providing the food security has been substantiated. An analysis of the dynamics and structure (both geographical and commodity of production volumes, consumption, exports and imports of meat has been conducted. The major producers, consumers, exporters and importers of meat in the context of globalization have been identified. The country-based features, patterns of consumption and imports of meat have been characterized. On the basis of calculated five indicators of concentration (coefficient of concentration, the Herfindahl-Hirschman index, coefficient of relative concentration, dispersion of logarithms of market shares, index of the maximum share the features of competition in the global market of producers and consumers of meat have been determined.

Enhancing and Transforming Global Learning Communities with Augmented Reality

Science.gov (United States)

Frydenberg, Mark; Andone, Diana

2018-01-01

Augmented and virtual reality applications bring new insights to real world objects and scenarios. This paper shares research results of the TalkTech project, an ongoing study investigating the impact of learning about new technologies as members of global communities. This study shares results of a collaborative learning project about augmented…

Globalization and the diffusion of ideas: why we should acknowledge the roots of mainstream ideas in global health.

Science.gov (United States)

Robert, Emilie; Hajizadeh, Mohammad; El-Bialy, Rowan; Bidisha, Sayema Haque

2014-06-01

Although globalization has created ample opportunities and spaces to share experiences and information, the diffusion of ideas, especially in global health, is primarily influenced by the unequal distribution of economic, political and scientific powers around the world. These ideas in global health are generally rooted in High-Income Countries (HICs), and then reach Low- and Middle-Income Countries (LMICs). We argue that acknowledging and addressing this invisible trend would contribute to a greater degree of open discussions in global health. This is expected to favor innovative, alternative, and culturally sound solutions for persistent health problems and reducing inequities.

Raising Virtual Laboratories in Australia onto global platforms

Science.gov (United States)

Wyborn, L. A.; Barker, M.; Fraser, R.; Evans, B. J. K.; Moloney, G.; Proctor, R.; Moise, A. F.; Hamish, H.

2016-12-01

Across the globe, Virtual Laboratories (VLs), Science Gateways (SGs), and Virtual Research Environments (VREs) are being developed that enable users who are not co-located to actively work together at various scales to share data, models, tools, software, workflows, best practices, etc. Outcomes range from enabling `long tail' researchers to more easily access specific data collections, to facilitating complex workflows on powerful supercomputers. In Australia, government funding has facilitated the development of a range of VLs through the National eResearch Collaborative Tools and Resources (NeCTAR) program. The VLs provide highly collaborative, research-domain oriented, integrated software infrastructures that meet user community needs. Twelve VLs have been funded since 2012, including the Virtual Geophysics Laboratory (VGL); Virtual Hazards, Impact and Risk Laboratory (VHIRL); Climate and Weather Science Laboratory (CWSLab); Marine Virtual Laboratory (MarVL); and Biodiversity and Climate Change Virtual Laboratory (BCCVL). These VLs share similar technical challenges, with common issues emerging on integration of tools, applications and access data collections via both cloud-based environments and other distributed resources. While each VL began with a focus on a specific research domain, communities of practice have now formed across the VLs around common issues, and facilitate identification of best practice case studies, and new standards. As a result, tools are now being shared where the VLs access data via data services using international standards such as ISO, OGC, W3C. The sharing of these approaches is starting to facilitate re-usability of infrastructure and is a step towards supporting interdisciplinary research. Whilst the focus of the VLs are Australia-centric, by using standards, these environments are able to be extended to analysis on other international datasets. Many VL datasets are subsets of global datasets and so extension to global is a

Cross-border insolvencies as a global economic problem | Stander ...

African Journals Online (AJOL)

As a result of the continuing expansion of international trade and investment, there has been an increase in the occurrence of cross-border insolvencies. National insolvency laws have not kept pace with the trend, and there is a need to develop an efficient and fair system for the administration of cross-border insolvencies.

Wind's share in global energy markets

International Nuclear Information System (INIS)

Madsen, B.T.

1997-01-01

The question of how great of a contribution wind power can really make to the world's energy needs is discussed. Emphasis up until recently has been mainly on improving wind turbine technology and siting practices as it is these that will provide an answer. The International Energy Agency predicts that world energy demand will increase by 30-50% by 2010. More countries than ever are either using wind power now or are preparing for its use. Wind power continues to improve its price competitiveness. There is enough wind to cover our energy needs many times over, according to some reports twice the world's electricity supply could be met by utilizing just 5-10% of areas identified as having average wind speeds of 5 m/s or greater - ignoring population centers, forests and specially protected areas. But a major limiting factor to utilizing the available wind resource is the established grid systems, which can only base 20% of supply on wind power. It is concluded that wind can contribute significantly to the world's energy needs in the next century and beyond. If wind, which has taken giant leaps in improving its competitiveness over the past 20 hears, can be a major energy contributor by early next century, other renewables such as solar and biomass might also evolve to become major contributors too. If so, renewables, including hydro, could conceivably cover 50% of our energy needs by the middle of the next century. Much will depend on decision-makers at the centers of power. For Europe and certain other areas of the world, policies governing cross-border trade of electricity as well as the framework for environmental protection related to energy production will determine the final outcome

Global ethics: the nature and purpose

Directory of Open Access Journals (Sweden)

Ye. M. Sulima

2017-07-01

Full Text Available The article discusses the factors of forming, the essence and importance of a global ethic as a moral regulator of intercultural interaction in the modern global society. The current global ethics built around basic common goals - peace and dignity of people, social justice, individual freedom, cultural pluralism, sustainable development - and allow plans to achieve different objectives, functioning set of identities and nationalities. It lies in increasing awareness of common fate, common human and social rights, interests, shared vulnerability to global environmental, social and political crises of necessity, consequent, to find common solutions and act on the basis of cultural dialogue and cooperation.

Language and Cross-Culture Understanding—Through Cross-Culture Study of the Word'Dragon'

Institute of Scientific and Technical Information of China (English)

周玲

2016-01-01

This essay contributes to the analysis of the significance of cross-culture understanding in connection with language. It is important and necessary to promote cross-cultural understanding in order to communicate with people from various cultural backgrounds with the development of globalization. This essay also gives the example of the word'dragon'to illustrate that the cross-culture understanding of language will make us communicate with each other more effectively.

Democracy, cognitive skill, and top 1% income share in the 21st century

OpenAIRE

Yamamura, Eiji

2015-01-01

Studies to date have shown that income concentration for the top 1% income share, the super-rich, has increased conspicuously in the 21st century. However, there is insufficient knowledge on how political factors and types of human capital influence income concentration. Using cross-country data from this century, I provide empirical evidence that shows that democracy and cognitive skill are negatively correlated to the top 1% income share.

A global reference for caesarean section rates (C-Model): a multicountry cross-sectional study.

Science.gov (United States)

Souza, J P; Betran, A P; Dumont, A; de Mucio, B; Gibbs Pickens, C M; Deneux-Tharaux, C; Ortiz-Panozo, E; Sullivan, E; Ota, E; Togoobaatar, G; Carroli, G; Knight, H; Zhang, J; Cecatti, J G; Vogel, J P; Jayaratne, K; Leal, M C; Gissler, M; Morisaki, N; Lack, N; Oladapo, O T; Tunçalp, Ö; Lumbiganon, P; Mori, R; Quintana, S; Costa Passos, A D; Marcolin, A C; Zongo, A; Blondel, B; Hernández, B; Hogue, C J; Prunet, C; Landman, C; Ochir, C; Cuesta, C; Pileggi-Castro, C; Walker, D; Alves, D; Abalos, E; Moises, Ecd; Vieira, E M; Duarte, G; Perdona, G; Gurol-Urganci, I; Takahiko, K; Moscovici, L; Campodonico, L; Oliveira-Ciabati, L; Laopaiboon, M; Danansuriya, M; Nakamura-Pereira, M; Costa, M L; Torloni, M R; Kramer, M R; Borges, P; Olkhanud, P B; Pérez-Cuevas, R; Agampodi, S B; Mittal, S; Serruya, S; Bataglia, V; Li, Z; Temmerman, M; Gülmezoglu, A M

2016-02-01

To generate a global reference for caesarean section (CS) rates at health facilities. Cross-sectional study. Health facilities from 43 countries. Thirty eight thousand three hundred and twenty-four women giving birth from 22 countries for model building and 10,045,875 women giving birth from 43 countries for model testing. We hypothesised that mathematical models could determine the relationship between clinical-obstetric characteristics and CS. These models generated probabilities of CS that could be compared with the observed CS rates. We devised a three-step approach to generate the global benchmark of CS rates at health facilities: creation of a multi-country reference population, building mathematical models, and testing these models. Area under the ROC curves, diagnostic odds ratio, expected CS rate, observed CS rate. According to the different versions of the model, areas under the ROC curves suggested a good discriminatory capacity of C-Model, with summary estimates ranging from 0.832 to 0.844. The C-Model was able to generate expected CS rates adjusted for the case-mix of the obstetric population. We have also prepared an e-calculator to facilitate use of C-Model (www.who.int/reproductivehealth/publications/maternal_perinatal_health/c-model/en/). This article describes the development of a global reference for CS rates. Based on maternal characteristics, this tool was able to generate an individualised expected CS rate for health facilities or groups of health facilities. With C-Model, obstetric teams, health system managers, health facilities, health insurance companies, and governments can produce a customised reference CS rate for assessing use (and overuse) of CS. The C-Model provides a customized benchmark for caesarean section rates in health facilities and systems. © 2015 World Health Organization; licensed by John Wiley & Sons Ltd on behalf of Royal College of Obstetricians and Gynaecologists.

Information Sharing and Knowledge Sharing as Communicative Activities

Science.gov (United States)

Savolainen, Reijo

2017-01-01

Introduction: This paper elaborates the picture of information sharing and knowledge sharing as forms of communicative activity. Method: A conceptual analysis was made to find out how researchers have approached information sharing and knowledge sharing from the perspectives of transmission and ritual. The findings are based on the analysis of one…

Does tariff escalation affect export shares: The case of cotton and coffee in global trade

OpenAIRE

Narayanan G, Badri; Khorana, Sangeeta

2011-01-01

Many studies show that Tariff Escalation (TE) lowers export shares in many of the processing sectors, given their higher level of protection. However, there are instances when the export shares of processed sectors are higher despite the existence of TE. We examine both these contrasting cases of TE in this paper. On the one hand, there is TE in coffee and coffee products in developing countries, which lead in raw coffee exports and lag in roasted coffee exports. On the other hand, there is a...

Psychosocial Factors of Dietitians' Intentions to Adopt Shared Decision Making Behaviours: A Cross-Sectional Survey

Science.gov (United States)

Deschênes, Sarah-Maude; Gagnon, Marie-Pierre; Légaré, France; Lapointe, Annie; Turcotte, Stéphane; Desroches, Sophie

2013-01-01

Objectives While shared decision making (SDM) promotes health-related decisions that are informed, value-based and adhered to, few studies report on theory-based approaches to SDM adoption by healthcare professionals. We aimed to identify the factors influencing dietitians' intentions to adopt two SDM behaviours: 1) present dietary treatment options to patients and 2) help patients clarify their values and preferences. Methods We conducted a cross-sectional postal survey based on the Theory of Planned Behaviour among 428 randomly selected dietitians working in clinical practice across the Province of Quebec, Canada. We performed descriptive analyses and multiple regression analyses to determine the variables that explained the variance in intention to perform the behaviours. Results A total of 203 dietitians completed the questionnaire. Their ages were from 23 to 66 and they had been practising dietetics for 15.4±11.1 years (mean ± SD). On a scale from 1 to 7 (from strongly disagree to strongly agree), dietitians' intentions to present dietary treatment options and to clarify their patients' values and preferences were 5.00±1.14 and 5.68±0.74, respectively. Perceived behavioural control (β = 0.56, ρadopt the two SDM behaviours studied. Factors influencing intention were different for each behaviour, except for perceived behavioural control which was common to both behaviours. Thus, perceived behavioural control could be a key factor in interventions aiming to encourage implementation of SDM by dietitians. PMID:23700484

Promoting Global Initiatives and Cross-Cultural Understanding in China

Science.gov (United States)

Brand, Susan Trostle; Snodgress, Faye

2012-01-01

As an "international" honor society in education, Kappa Delta Pi (KDP) recognizes the importance of encouraging and promoting education internationally in the 21st century. The challenge shared by educators in many countries is to achieve higher levels of learning for all students. Committed educators around the globe are already working…

The Latest Books on Globalization

Directory of Open Access Journals (Sweden)

Elia Zaru

2016-12-01

Full Text Available The latest books published on globalization raise interesting issues which reflect upon the very complexity of the process we are facing. In The Great Convergence: Information Technology and the New Globalization Richard Baldwin proposes a history of globalization divided into two stages. As Baldwin argues, the process of globalization has to be divided into “old” and “new” age. The “old” globalization took place between 1820 and 1990. It was characterized by the “great divergence”, that is by the centralization of world income in today’s wealthy nations. However, since 1990 the sharing of world income has plummeted to where it was in 1900. According to Baldwin, this reversal of fortune is a symptom of a shift in the globalization process. The “new” globalization, driven by information technology, has combined high tech with low wages, and lead simultaneously to the industrialization of developing nations and deindustrialization of developed ones. This is the “great convergence”: in the “new” globalization rich and developing nations are alike and they face equal global challenges.

Polycentrism in Global Health Governance Scholarship

Science.gov (United States)

Tosun, Jale

2018-01-01

Drawing on an in-depth analysis of eight global health networks, a recent essay in this journal argued that global health networks face four challenges to their effectiveness: problem definition, positioning, coalition-building, and governance. While sharing the argument of the essay concerned, in this commentary, we argue that these analytical concepts can be used to explicate a concept that has implicitly been used in global health governance scholarship for quite a few years. While already prominent in the discussion of climate change governance, for instance, global health governance scholarship could make progress by looking at global health governance as being polycentric. Concisely, polycentric forms of governance mix scales, mechanisms, and actors. Drawing on the essay, we propose a polycentric approach to the study of global health governance that incorporates coalitionbuilding tactics, internal governance and global political priority as explanatory factors. PMID:29325406

N-Alkylated dinitrones from isosorbide as cross-linkers for unsaturated bio-based polyesters

Directory of Open Access Journals (Sweden)

Oliver Goerz

2014-04-01

Full Text Available Isosorbide was esterified with acryloyl chloride and crotonic acid yielding isosorbide diacrylate (9a and isosorbide dicrotonate (9b, which were reacted with benzaldehyde oxime in the presence of zinc(II iodide and boron triflouride etherate as catalysts to obtain N-alkylated dinitrones 10a/b. Poly(isosorbide itaconite -co- succinate 13 as a bio-based unsaturated polyester was cross-linked by a 1,3-dipolar cycloaddition with the received dinitrones 10a/b. The 1,3-dipolar cycloaddition led to a strong change of the mechanical properties which were investigated by rheological measurements. Nitrones derived from methyl acrylate (3a and methyl crotonate (3b were used as model systems and reacted with dimethyl itaconate to further characterize the 1,3-dipolaric cycloaddition.

Global Programs

Science.gov (United States)

Lindberg Christensen, Lars; Russo, P.

2009-05-01

IYA2009 is a global collaboration between almost 140 nations and more than 50 international organisations sharing the same vision. Besides the common brand, mission, vision and goals, IAU established eleven cornerstones programmes to support the different IYA2009 stakeholder to organize events, activities under a common umbrella. These are global activities centred on specific themes and are aligned with IYA2009's main goals. Whether it is the support and promotion of women in astronomy, the preservation of dark-sky sites around the world or educating and explaining the workings of the Universe to millions, the eleven Cornerstones are key elements in the success of IYA2009. However, the process of implementing global projects across cultural boundaries is challenging and needs central coordination to preserve the pre-established goals. During this talk we will examine the ups and downs of coordinating such a project and present an overview of the principal achievements for the Cornerstones so far.

Immunological cross-reactivity of the major allergen from perennial ryegrass (Lolium perenne), Lol p I, and the cysteine proteinase, bromelain.

Science.gov (United States)

Pike, R N; Bagarozzi, D; Travis, J

1997-04-01

Antibodies prepared in rabbits against the major allergen from ryegrass (Lolium perenne), Lol p I, cross-reacted with the cysteine proteinase bromelain from pineapple and vice versa. Deglycosylation of the proteins showed that the cross-reaction was based on recognition of the carbohydrate moiety of the allergen, but for bromelain the cross-reaction was most likely due to a combination of factors. The results indicate that the carbohydrate residues from these allergens play an important role in cross-reactions found between them and possibly those from other species.

Polycentrism in Global Health Governance Scholarship; Comment on “Four Challenges That Global Health Networks Face”

Directory of Open Access Journals (Sweden)

Jale Tosun

2018-01-01

Full Text Available Drawing on an in-depth analysis of eight global health networks, a recent essay in this journal argued that global health networks face four challenges to their effectiveness: problem definition, positioning, coalition-building, and governance. While sharing the argument of the essay concerned, in this commentary, we argue that these analytical concepts can be used to explicate a concept that has implicitly been used in global health governance scholarship for quite a few years. While already prominent in the discussion of climate change governance, for instance, global health governance scholarship could make progress by looking at global health governance as being polycentric. Concisely, polycentric forms of governance mix scales, mechanisms, and actors. Drawing on the essay, we propose a polycentric approach to the study of global health governance that incorporates coalitionbuilding tactics, internal governance and global political priority as explanatory factors.

Genetic Variation in Schizophrenia Liability is Shared With Intellectual Ability and Brain Structure.

Science.gov (United States)

Bohlken, Marc M; Brouwer, Rachel M; Mandl, René C W; Kahn, René S; Hulshoff Pol, Hilleke E

2016-09-01

Alterations in intellectual ability and brain structure are important genetic markers for schizophrenia liability. How variations in these phenotypes interact with variance in schizophrenia liability due to genetic or environmental factors is an area of active investigation. Studying these genetic markers using a multivariate twin modeling approach can provide novel leads for (genetic) pathways of schizophrenia development. In a sample of 70 twins discordant for schizophrenia and 130 healthy control twins, structural equation modeling was applied to quantify unique contributions of genetic and environmental factors on human brain structure (cortical thickness, cortical surface and global white matter fractional anisotropy [FA]), intellectual ability and schizophrenia liability. In total, up to 28.1% of the genetic variance (22.8% of total variance) in schizophrenia liability was shared with intelligence quotient (IQ), global-FA, cortical thickness, and cortical surface. The strongest contributor was IQ, sharing on average 16.4% of the genetic variance in schizophrenia liability, followed by cortical thickness (6.3%), global-FA (4.7%) and cortical surface (0.5%). Furthermore, we found that up to 57.4% of the variation due to environmental factors (4.6% of total variance) in schizophrenia was shared with IQ (34.2%) and cortical surface (13.4%). Intellectual ability, FA and cortical thickness show significant and independent shared genetic variance with schizophrenia liability. This suggests that measuring brain-imaging phenotypes helps explain genetic variance in schizophrenia liability that is not captured by variation in IQ. © The Author 2016. Published by Oxford University Press on behalf of the Maryland Psychiatric Research Center. All rights reserved. For permissions, please email: journals.permissions@oup.com.

Cross-Cultural Interpretations of Curricular Contextual Crossings

Science.gov (United States)

Schlein, Candace; Garii, Barbara

2011-01-01

Teachers--who are generally representatives of the cultural mainstream--are expected to use global experiences to become culturally enhanced and to bring these enhancements back to their classrooms. In this article, the authors discuss a cross-cultural exploration of investigations into the experiences of Canadian and U.S. educators with…

Telehealth solutions to enable global collaboration in rheumatic heart disease screening.

Science.gov (United States)

Lopes, Eduardo Lv; Beaton, Andrea Z; Nascimento, Bruno R; Tompsett, Alison; Dos Santos, Julia Pa; Perlman, Lindsay; Diamantino, Adriana C; Oliveira, Kaciane Kb; Oliveira, Cassio M; Nunes, Maria do Carmo P; Bonisson, Leonardo; Ribeiro, Antônio Lp; Sable, Craig

2018-02-01

Background The global burden of rheumatic heart disease is nearly 33 million people. Telemedicine, using cloud-server technology, provides an ideal solution for sharing images performed by non-physicians with cardiologists who are experts in rheumatic heart disease. Objective We describe our experience in using telemedicine to support a large rheumatic heart disease outreach screening programme in the Brazilian state of Minas Gerais. Methods The Programa de Rastreamento da Valvopatia Reumática (PROVAR) is a prospective cross-sectional study aimed at gathering epidemiological data on the burden of rheumatic heart disease in Minas Gerais and testing of a non-expert, telemedicine-supported model of outreach rheumatic heart disease screening. The primary goal is to enable expert support of remote rheumatic heart disease outreach through cloud-based sharing of echocardiographic images between Minas Gerais and Washington. Secondary goals include (a) developing and sharing online training modules for non-physicians in echocardiography performance and interpretation and (b) utilising a secure web-based system to share clinical and research data. Results PROVAR included 4615 studies that were performed by non-experts at 21 schools and shared via cloud-telemedicine technology. Latent rheumatic heart disease was found in 251 subjects (4.2% of subjects: 3.7% borderline and 0.5% definite disease). Of the studies, 50% were preformed on full functional echocardiography machines and transmitted via Digital Imaging and Communications in Medicine (DICOM) and 50% were performed on handheld echocardiography machines and transferred via a secure Dropbox connection. The average time between study performance date and interpretation was 10 days. There was 100% success in initial image transfer. Less than 1% of studies performed by non-experts could not be interpreted. Discussion A sustainable, low-cost telehealth model, using task-shifting with non-medical personal in low and middle

From Planetary Boundaries to national fair shares of the global safe operating space - How can the scales be bridged?

Science.gov (United States)

Häyhä, Tiina; Cornell, Sarah; Lucas, Paul; van Vuuren, Detlef; Hoff, Holger

2016-04-01

The planetary boundaries framework proposes precautionary quantitative global limits to the anthropogenic perturbation of crucial Earth system processes. In this way, it marks out a planetary 'safe operating space' for human activities. However, decisions regarding resource use and emissions are mostly made at much smaller scales, mostly by (sub-)national and regional governments, businesses, and other local actors. To operationalize the planetary boundaries, they need to be translated into and aligned with targets that are relevant at these smaller scales. In this paper, we develop a framework that addresses the three dimension of bridging across scales: biophysical, socio-economic and ethical, to provide a consistent universally applicable approach for translating the planetary boundaries into national level context-specific and fair shares of the safe operating space. We discuss our findings in the context of previous studies and their implications for future analyses and policymaking. In this way, we help link the planetary boundaries framework to widely- applied operational and policy concepts for more robust strong sustainability decision-making.

Building Global Support for Open Data Access

Science.gov (United States)

Key, E.; Samors, R. J.; Seltzer, C. E.; Orr, B. J.

2017-12-01

The Belmont Forum, a global partnership of funding organizations, international science councils, and regional consortia is committed to the advancement of international transdisciplinary research providing knowledge for understanding, mitigating and adapting to global environmental change. The Forum is also committed to ensuring appropriate, recognizable credit is awarded to the creators of that data, each and every time it is used. At its 2015 plenary meeting, the Belmont Forum agreed on and adopted an open data policy and principles. The principles are designed to widen access to data and promote its long-term preservation in global change research; help improve data management and exploitation; coordinate and integrate disparate organizational and technical elements; fill critical global e-infrastructure gaps; share best practices; and foster new data literacy. To help implement the policy and principles, the Belmont Forum has established the e-Infrastructures and Data Management (e-I&DM) Initiative which will leverage existing knowledge and resources to illuminate achievable, reproducible systems for effective, sustainable data management practices. The overall objective of the e-I&DM Initiative is to provide advice and recommendations to the Belmont Forum member and partner organizations regarding policies, programs, procedures that could be adopted to accelerate open data sharing, data reproducibility, data curation, and other aspects of long-term data management and access. This presentation will explore current Belmont Forum activities through the e-I&DM Initiative to develop policies and practices that could be adopted by funders, publishers and researchers alike that will lead to increased data sharing with more widespread data citation/attribution - giving credit where credit is due.

Extending Current Theories of Cross-Boundary Information Sharing and Integration: A Case Study of Taiwan e-Government

Science.gov (United States)

Yang, Tung-Mou

2011-01-01

Information sharing and integration has long been considered an important approach for increasing organizational efficiency and performance. With advancements in information and communication technologies, sharing and integrating information across organizations becomes more attractive and practical to organizations. However, achieving…

Development of a Reduced-Order Model for Reacting Gas-Solids Flow using Proper Orthogonal Decomposition

Energy Technology Data Exchange (ETDEWEB)

McDaniel, Dwayne [Florida International Univ., Miami, FL (United States); Dulikravich, George [Florida International Univ., Miami, FL (United States); Cizmas, Paul [Florida International Univ., Miami, FL (United States)

2017-11-27

This report summarizes the objectives, tasks and accomplishments made during the three year duration of this research project. The report presents the results obtained by applying advanced computational techniques to develop reduced-order models (ROMs) in the case of reacting multiphase flows based on high fidelity numerical simulation of gas-solids flow structures in risers and vertical columns obtained by the Multiphase Flow with Interphase eXchanges (MFIX) software. The research includes a numerical investigation of reacting and non-reacting gas-solids flow systems and computational analysis that will involve model development to accelerate the scale-up process for the design of fluidization systems by providing accurate solutions that match the full-scale models. The computational work contributes to the development of a methodology for obtaining ROMs that is applicable to the system of gas-solid flows. Finally, the validity of the developed ROMs is evaluated by comparing the results against those obtained using the MFIX code. Additionally, the robustness of existing POD-based ROMs for multiphase flows is improved by avoiding non-physical solutions of the gas void fraction and ensuring that the reduced kinetics models used for reactive flows in fluidized beds are thermodynamically consistent.

MHD flow and heat transfer of a viscous reacting fluid over a ...

African Journals Online (AJOL)

This paper presents a boundary layer flow analysis for a viscous, incompressible, electrically conducting reacting fluid over a stretching sheet in the presence of a magnetic field. It is shown that the Hartmann, Prandtl and the Eckert numbers have effect on the velocity and temperature fields. Journal of the Nigerian ...

Propel: A Discontinuous-Galerkin Finite Element Code for Solving the Reacting Navier-Stokes Equations

Science.gov (United States)

Johnson, Ryan; Kercher, Andrew; Schwer, Douglas; Corrigan, Andrew; Kailasanath, Kazhikathra

2017-11-01

This presentation focuses on the development of a Discontinuous Galerkin (DG) method for application to chemically reacting flows. The in-house code, called Propel, was developed by the Laboratory of Computational Physics and Fluid Dynamics at the Naval Research Laboratory. It was designed specifically for developing advanced multi-dimensional algorithms to run efficiently on new and innovative architectures such as GPUs. For these results, Propel solves for convection and diffusion simultaneously with detailed transport and thermodynamics. Chemistry is currently solved in a time-split approach using Strang-splitting with finite element DG time integration of chemical source terms. Results presented here show canonical unsteady reacting flow cases, such as co-flow and splitter plate, and we report performance for higher order DG on CPU and GPUs.

Why Targets of Economic Sanctions React Differently: Reference Point Effects on North Korea and Libya

Directory of Open Access Journals (Sweden)

Jiyoun Park

2017-06-01

Full Text Available The international community has frequently introduced economic sanctions to curb the proliferation of weapons of mass destruction, to which each target nation has reacted differently. This paper explores the reasons why each target of economic sanctions reacts differently by specif- ically building a model based on reference point effects, and by analyzing the cases of North Korea and Libya. According to the results, when the reference point level increases, as in the case of North Korea, the target resists more firmly; on the other hand, when the reference point decreases, like in the case of Libya, the target resists more subtly.

Aligning Learner Preferences for Information Seeking, Information Sharing and Mobile Technologies

Science.gov (United States)

Mills, Leila A.; Knezek, Gerald; Khaddage, Ferial

2012-01-01

This paper reports on the development of a new information communications technology (ICT) learning preference survey, its cross-validation with attitudes towards mobile learning, and new perspectives on information seeking, information sharing, and mobile access derived from the relationships uncovered. The Information and Communications…

Incentive Mechanism Model Design for Sharing of Information Resources in Rural Areas

OpenAIRE

Gao, Xirong; Shan, Lingling

2013-01-01

In order to solve the issues concerning the cross-unit sharing of information resources in rural areas, we analyze the incentive problem of the sharing of information resources in rural areas using the incentive theory method; establish corresponding incentive mechanism model (It is divided into positive incentive model and negative incentive model, and only when the two models guarantee each other and are used at the same time can they be effective). Based on this, we put forward the institu...

The Responsive Environmental Assessment for Classroom Teaching (REACT): the dimensionality of student perceptions of the instructional environment.

Science.gov (United States)

Nelson, Peter M; Demers, Joseph A; Christ, Theodore J

2014-06-01

This study details the initial development of the Responsive Environmental Assessment for Classroom Teachers (REACT). REACT was developed as a questionnaire to evaluate student perceptions of the classroom teaching environment. Researchers engaged in an iterative process to develop, field test, and analyze student responses on 100 rating-scale items. Participants included 1,465 middle school students across 48 classrooms in the Midwest. Item analysis, including exploratory and confirmatory factor analysis, was used to refine a 27-item scale with a second-order factor structure. Results support the interpretation of a single general dimension of the Classroom Teaching Environment with 6 subscale dimensions: Positive Reinforcement, Instructional Presentation, Goal Setting, Differentiated Instruction, Formative Feedback, and Instructional Enjoyment. Applications of REACT in research and practice are discussed along with implications for future research and the development of classroom environment measures. PsycINFO Database Record (c) 2014 APA, all rights reserved.

Developing Global Transformational Leaders

DEFF Research Database (Denmark)

Ramsey, Jase R.; Rutti, Raina M.; Lorenz, Melanie P.

2016-01-01

Despite significant increases in training and development of global managers, little is known about the precursors of transformational leadership in Multilatinas. While prior cross-cultural literature suggests that being an autocratic leader is ideal in Multilatinas, using transformational...... leadership theory, we argue that global leaders of Multilatinas embrace a more humanistic approach to leadership because of the importance of relationships between leaders and their followers. Additionally, we argue that global leaders with high levels of cultural intelligence will have high levels...

Quantifying the conservation gains from shared access to linear infrastructure.

Science.gov (United States)

Runge, Claire A; Tulloch, Ayesha I T; Gordon, Ascelin; Rhodes, Jonathan R

2017-12-01

The proliferation of linear infrastructure such as roads and railways is a major global driver of cumulative biodiversity loss. One strategy for reducing habitat loss associated with development is to encourage linear infrastructure providers and users to share infrastructure networks. We quantified the reductions in biodiversity impact and capital costs under linear infrastructure sharing of a range of potential mine to port transportation links for 47 mine locations operated by 28 separate companies in the Upper Spencer Gulf Region of South Australia. We mapped transport links based on least-cost pathways for different levels of linear-infrastructure sharing and used expert-elicited impacts of linear infrastructure to estimate the consequences for biodiversity. Capital costs were calculated based on estimates of construction costs, compensation payments, and transaction costs. We evaluated proposed mine-port links by comparing biodiversity impacts and capital costs across 3 scenarios: an independent scenario, where no infrastructure is shared; a restricted-access scenario, where the largest mining companies share infrastructure but exclude smaller mining companies from sharing; and a shared scenario where all mining companies share linear infrastructure. Fully shared development of linear infrastructure reduced overall biodiversity impacts by 76% and reduced capital costs by 64% compared with the independent scenario. However, there was considerable variation among companies. Our restricted-access scenario showed only modest biodiversity benefits relative to the independent scenario, indicating that reductions are likely to be limited if the dominant mining companies restrict access to infrastructure, which often occurs without policies that promote sharing of infrastructure. Our research helps illuminate the circumstances under which infrastructure sharing can minimize the biodiversity impacts of development. © 2017 The Authors. Conservation Biology published

Did Globalization Influence Credit Market Deregulation

OpenAIRE

Eppinger, Peter; Potrafke, Niklas

2015-01-01

We investigate whether globalization influenced credit market deregulation over the period 1970-2010. Globalization is measured by the KOF indices of globalization. Credit market deregulation is measured by the credit market freedom indicators of the Fraser Institute. The results from both cross-sectional and panel regressions using ordinary least squares indicate a positive correlation between globalization and credit market deregulation. We account for reverse causality by using predicted t...

Modified gum arabic cross-linked gelatin scaffold for biomedical applications

International Nuclear Information System (INIS)

Sarika, P.R.; Cinthya, Kuriakose; Jayakrishnan, A.; Anilkumar, P.R.; James, Nirmala Rachel

2014-01-01

The present work deals with development of modified gum arabic cross-linked gelatin scaffold for cell culture. A new biocompatible scaffold was developed by cross-linking gelatin (Gel) with gum arabic, a polysaccharide. Gum arabic was subjected to periodate oxidation to obtain gum arabic aldehyde (GAA). GAA was reacted with gelatin under appropriate pH to prepare the cross-linked hydrogel. Cross-linking occurred due to Schiff's base reaction between aldehyde groups of oxidized gum arabic and amino groups of gelatin. The scaffold prepared from the hydrogel was characterized by swelling properties, degree of cross-linking, in vitro degradation and scanning electron microscopy (SEM). Cytocompatibility evaluation using L-929 and HepG2 cells confirmed non-cytotoxic and non-adherent nature of the scaffold. These properties are essential for generating multicellular spheroids and hence the scaffold is proposed to be a suitable candidate for spheroid cell culture. - Highlights: • Gum arabic cross-linked gelatin scaffold was developed for tissue engineering. • Cross-linking was achieved by Schiff's base reaction. • The scaffold is non-cytotoxic and non adherent to fibroblast and hepatocytes. • The scaffolds are potential candidates for spheroid cell culture

Modified gum arabic cross-linked gelatin scaffold for biomedical applications

Energy Technology Data Exchange (ETDEWEB)

Sarika, P.R. [Department of Chemistry, Indian Institute of Space Science and Technology, Valiamala, Thiruvananthapuram, Kerala 695 547 (India); Cinthya, Kuriakose [Tissue Culture Laboratory, Biomedical Technology Wing, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Poojappura, Thiruvananthapuram, Kerala 695 012 (India); Jayakrishnan, A. [Department of Biotechnology, Indian Institute of Technology Madras, Chennai 600 036 (India); Anilkumar, P.R., E-mail: anilkumarpr@sctimst.ac.in [Tissue Culture Laboratory, Biomedical Technology Wing, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Poojappura, Thiruvananthapuram, Kerala 695 012 (India); James, Nirmala Rachel, E-mail: nirmala@iist.ac.in [Department of Chemistry, Indian Institute of Space Science and Technology, Valiamala, Thiruvananthapuram, Kerala 695 547 (India)

2014-10-01

The present work deals with development of modified gum arabic cross-linked gelatin scaffold for cell culture. A new biocompatible scaffold was developed by cross-linking gelatin (Gel) with gum arabic, a polysaccharide. Gum arabic was subjected to periodate oxidation to obtain gum arabic aldehyde (GAA). GAA was reacted with gelatin under appropriate pH to prepare the cross-linked hydrogel. Cross-linking occurred due to Schiff's base reaction between aldehyde groups of oxidized gum arabic and amino groups of gelatin. The scaffold prepared from the hydrogel was characterized by swelling properties, degree of cross-linking, in vitro degradation and scanning electron microscopy (SEM). Cytocompatibility evaluation using L-929 and HepG2 cells confirmed non-cytotoxic and non-adherent nature of the scaffold. These properties are essential for generating multicellular spheroids and hence the scaffold is proposed to be a suitable candidate for spheroid cell culture. - Highlights: • Gum arabic cross-linked gelatin scaffold was developed for tissue engineering. • Cross-linking was achieved by Schiff's base reaction. • The scaffold is non-cytotoxic and non adherent to fibroblast and hepatocytes. • The scaffolds are potential candidates for spheroid cell culture.

Beyond the 'new cross-cultural psychiatry': cultural biology, discursive psychology and the ironies of globalization.

Science.gov (United States)

Kirmayer, Laurence J

2006-03-01

The 'new cross-cultural psychiatry' heralded by Kleinman in 1977 promised a revitalized tradition that gave due respect to cultural difference and did not export psychiatric theories that were themselves culture bound. In the ensuing years, the view of culture within anthropology has continued to change, along with our understanding of the relationship of biological processes to cultural diversity, and the global political economic contexts in which mental health care is delivered. This article considers the implications of these new notions of culture, biology and the context of practice for theory in cultural psychiatry. The future of cultural psychiatry lies in advancing a broad perspective that: (a) is inherently multidisciplinary (involving psychiatric epidemiology, medical anthropology and sociology, cognitive science and social psychology), breaking down the nature/culture dichotomy with an integrative view of culture as a core feature of human biology, while remaining alert to cultural constructions of biological theory; (b) attends to psychological processes but understands these as not exclusively located within the individual but as including discursive processes that are fundamentally social; and (c) critically examines the interaction of both local and global systems of knowledge and power. Globalization has brought with it many ironies for cultural psychiatry: Transnational migrations have resulted in cultural hybridization at the same time as ethnicity has become more salient; the call for evidence-based medicine has been used to limit the impact of cultural research; and cultural psychiatry itself has been co-opted by pharmaceutical companies to inform marketing campaigns to promote conventional treatments for new populations. Cultural psychiatry must address these ironies to develop the self-critical awareness and flexibility needed to deliver humane care in shifting contexts.

Wrox SharePoint 2010 SharePoint911 three-pack

CERN Document Server

Klindt, Todd; Mason, Jennifer; Rogers, Laura; Drisgill, Randy; Ross, John; Riemann, Larry; Perran, Amanda; Perran, Shane; Sanford, Jacob J; Stubbs, Paul; Caravajal, Steve

2012-01-01

The Wrox SharePoint 2010 SharePoint911 Three-Pack combines the contents of three full e-books written by the experts from SharePoint911.  That's over 1800 pages of hands-on advice from Todd Klindt, Shane Young, Laura Rogers, Randy Drisgill, Jennifer Mason, John Ross, and Larry Riemann, among others. In Beginning SharePoint 2010: Building Business Solutions with SharePoint (ISBN 978-0-470-61789-2) by Amanda Perran, Shane Perran, Jennifer Mason, and Laura Rogers, readers learn the core concepts, terminology, and features of SharePoint 2010. In Professiona

Sticky tunes: how do people react to involuntary musical imagery?

Directory of Open Access Journals (Sweden)

Victoria J Williamson

Full Text Available The vast majority of people experience involuntary musical imagery (INMI or 'earworms'; perceptions of spontaneous, repetitive musical sound in the absence of an external source. The majority of INMI episodes are not bothersome, while some cause disruption ranging from distraction to anxiety and distress. To date, little is known about how the majority of people react to INMI, in particular whether evaluation of the experience impacts on chosen response behaviours or if attempts at controlling INMI are successful or not. The present study classified 1046 reports of how people react to INMI episodes. Two laboratories in Finland and the UK conducted an identical qualitative analysis protocol on reports of INMI reactions and derived visual descriptive models of the outcomes using grounded theory techniques. Combined analysis carried out across the two studies confirmed that many INMI episodes were considered neutral or pleasant, with passive acceptance and enjoyment being among the most popular response behaviours. A significant number of people, however, reported on attempts to cope with unwanted INMI. The most popular and effective behaviours in response to INMI were seeking out the tune in question, and musical or verbal distraction. The outcomes of this study contribute to our understanding of the aetiology of INMI, in particular within the framework of memory theory, and present testable hypotheses for future research on successful INMI coping strategies.

Sticky Tunes: How Do People React to Involuntary Musical Imagery?

Science.gov (United States)

Williamson, Victoria J.; Liikkanen, Lassi A.; Jakubowski, Kelly; Stewart, Lauren

2014-01-01

The vast majority of people experience involuntary musical imagery (INMI) or ‘earworms’; perceptions of spontaneous, repetitive musical sound in the absence of an external source. The majority of INMI episodes are not bothersome, while some cause disruption ranging from distraction to anxiety and distress. To date, little is known about how the majority of people react to INMI, in particular whether evaluation of the experience impacts on chosen response behaviours or if attempts at controlling INMI are successful or not. The present study classified 1046 reports of how people react to INMI episodes. Two laboratories in Finland and the UK conducted an identical qualitative analysis protocol on reports of INMI reactions and derived visual descriptive models of the outcomes using grounded theory techniques. Combined analysis carried out across the two studies confirmed that many INMI episodes were considered neutral or pleasant, with passive acceptance and enjoyment being among the most popular response behaviours. A significant number of people, however, reported on attempts to cope with unwanted INMI. The most popular and effective behaviours in response to INMI were seeking out the tune in question, and musical or verbal distraction. The outcomes of this study contribute to our understanding of the aetiology of INMI, in particular within the framework of memory theory, and present testable hypotheses for future research on successful INMI coping strategies. PMID:24497938

Direct numerical simulation of an isothermal reacting turbulent wall-jet

Science.gov (United States)

Pouransari, Zeinab; Brethouwer, Geert; Johansson, Arne V.

2011-08-01

In the present investigation, Direct Numerical Simulation (DNS) is used to study a binary irreversible and isothermal reaction in a plane turbulent wall-jet. The flow is compressible and a single-step global reaction between an oxidizer and a fuel species is solved. The inlet based Reynolds, Schmidt, and Mach numbers of the wall-jet are Re = 2000, Sc = 0.72, and M = 0.5, respectively, and a constant coflow velocity is applied above the jet. At the inlet, fuel and oxidizer enter the domain separately in a non-premixed manner. The turbulent structures of the velocity field show the common streaky patterns near the wall, while a somewhat patchy or spotty pattern is observed for the scalars and the reaction rate fluctuations in the near-wall region. The reaction mainly occurs in the upper shear layer in thin highly convoluted reaction zones, but it also takes place close to the wall. Analysis of turbulence and reaction statistics confirms the observations in the instantaneous snapshots, regarding the intermittent character of the reaction rate near the wall. A detailed study of the probability density functions of the reacting scalars and comparison to that of the passive scalar throughout the domain reveals the significance of the reaction influence as well as the wall effects on the scalar distributions. The higher order moments of both the velocities and the scalar concentrations are analyzed and show a satisfactory agreement with experiments. The simulations show that the reaction can both enhance and reduce the dissipation of fuel scalar, since there are two competing effects; on the one hand, the reaction causes sharper scalar gradients and thus a higher dissipation rate, on the other hand, the reaction consumes the fuel scalar thereby reducing the scalar dissipation.

SQL Triggers Reacting on Time Events: An Extension Proposal

Science.gov (United States)

Behrend, Andreas; Dorau, Christian; Manthey, Rainer

Being able to activate triggers at timepoints reached or after time intervals elapsed has been acknowledged by many authors as a valuable functionality of a DBMS. Recently, the interest in time-based triggers has been renewed in the context of data stream monitoring. However, up till now SQL triggers react to data changes only, even though research proposals and prototypes have been supporting several other event types, in particular time-based ones, since long. We therefore propose a seamless extension of the SQL trigger concept by time-based triggers, focussing on semantic issues arising from such an extension.

Pervasive sharing of genetic effects in autoimmune disease.

Directory of Open Access Journals (Sweden)

Chris Cotsapas

2011-08-01

Full Text Available Genome-wide association (GWA studies have identified numerous, replicable, genetic associations between common single nucleotide polymorphisms (SNPs and risk of common autoimmune and inflammatory (immune-mediated diseases, some of which are shared between two diseases. Along with epidemiological and clinical evidence, this suggests that some genetic risk factors may be shared across diseases-as is the case with alleles in the Major Histocompatibility Locus. In this work we evaluate the extent of this sharing for 107 immune disease-risk SNPs in seven diseases: celiac disease, Crohn's disease, multiple sclerosis, psoriasis, rheumatoid arthritis, systemic lupus erythematosus, and type 1 diabetes. We have developed a novel statistic for Cross Phenotype Meta-Analysis (CPMA which detects association of a SNP to multiple, but not necessarily all, phenotypes. With it, we find evidence that 47/107 (44% immune-mediated disease risk SNPs are associated to multiple-but not all-immune-mediated diseases (SNP-wise P(CPMA<0.01. We also show that distinct groups of interacting proteins are encoded near SNPs which predispose to the same subsets of diseases; we propose these as the mechanistic basis of shared disease risk. We are thus able to leverage genetic data across diseases to construct biological hypotheses about the underlying mechanism of pathogenesis.

‘Sharing the Pie’: Taxing multinationals in a global market

OpenAIRE

Wilde, Maarten

2015-01-01

markdownabstract__Abstract__ The current international corporate tax regime for taxing the business proceeds of firms operates arbitrarily. The aggregates of the nation states’ international corporate tax systems seem to distort a global efficient allocation of resources. The current model of corporate taxation finds its origins in the 1920s. It well suited the economic realities of the early days of international trade and commerce; the times when international business primarily revolved ar...

Methane reacts with heteropolyacids chemisorbed on silica to produce acetic acid under soft conditions

KAUST Repository

Sun, Miao; Abou-Hamad, Edy; Rossini, Aaron J.; Zhang, Jizhe; Lesage, Anne; Zhu, Haibo; Pelletier, Jeremie; Emsley, Lyndon; Caps, Valerie; Basset, Jean-Marie

2013-01-01

Selective functionalization of methane at moderate temperature is of crucial economic, environmental, and scientific importance. Here, we report that methane reacts with heteropolyacids (HPAs) chemisorbed on silica to produce acetic acid under soft

Thinking Globally when Teaching Locally

Science.gov (United States)

Van Reken, Ruth E.; Rushmore, Sally

2009-01-01

Advances in science and technology, globalization of trade, international competition for markets, ethnic conflicts, and the limits of the planet's ecosystem have brought global issues and the people of the world to doorsteps and classrooms. With the increasing interaction among peoples of the world, skills in cross-cultural communication,…

Knowledge sharing through social media: Investigating trends and technologies in a global marketing and advertising research company

Directory of Open Access Journals (Sweden)

Dina Adamovic

2012-07-01

Objective: The objective of this study was to investigate trends in knowledge-sharing technologies in Nielsen. Method: The researchers distributed semi-structured questionnaires to a sample of employees in Nielsen’s Television Audience Measurement Department. They also conducted interviews with specific employees in this department to gain a better understanding of employees’ attitudes toward, and perceptions of, the use of social media tools for creating a knowledgesharing culture at Nielsen. The researchers validated the data to see whether it could support the research and used triangulation to create a holistic view of the data they received from the questionnaires. Results: The findings of the study revealed that respondents had a positive attitude to sharing knowledge with one another through using social media tools. However, some respondents thought that technology, in general, was ‘the tree of good and evil’. The survey findings showed that Nielsen did have social media tools. However, not all employees were aware of these tools or were willing to use the tools to share knowledge. This study highlighted the possible advantages of the social media for sharing knowledge and how Nielsen could use the tools more widely. Conclusion: In order for a knowledge sharing culture to thrive at Nielsen, its employees need to engage more with social media tools in their business practices.

Recent advances in ultrafast-laser-based spectroscopy and imaging for reacting plasmas and flames

Science.gov (United States)

Patnaik, Anil K.; Adamovich, Igor; Gord, James R.; Roy, Sukesh

2017-10-01

Reacting flows and plasmas are prevalent in a wide array of systems involving defense, commercial, space, energy, medical, and consumer products. Understanding the complex physical and chemical processes involving reacting flows and plasmas requires measurements of key parameters, such as temperature, pressure, electric field, velocity, and number densities of chemical species. Time-resolved measurements of key chemical species and temperature are required to determine kinetics related to the chemical reactions and transient phenomena. Laser-based, noninvasive linear and nonlinear spectroscopic approaches have proved to be very valuable in providing key insights into the physico-chemical processes governing reacting flows and plasmas as well as validating numerical models. The advent of kilohertz rate amplified femtosecond lasers has expanded the multidimensional imaging of key atomic species such as H, O, and N in a significant way, providing unprecedented insight into preferential diffusion and production of these species under chemical reactions or electric-field driven processes. These lasers not only provide 2D imaging of chemical species but have the ability to perform measurements free of various interferences. Moreover, these lasers allow 1D and 2D temperature-field measurements, which were quite unimaginable only a few years ago. The rapid growth of the ultrafast-laser-based spectroscopic measurements has been fueled by the need to achieve the following when measurements are performed in reacting flows and plasmas. They are: (1) interference-free measurements (collision broadening, photolytic dissociation, Stark broadening, etc), (2) time-resolved single-shot measurements at a rate of 1-10 kHz, (3) spatially-resolved measurements, (4) higher dimensionality (line, planar, or volumetric), and (5) simultaneous detection of multiple species. The overarching goal of this article is to review the current state-of-the-art ultrafast-laser-based spectroscopic

Beginning SharePoint 2010 Administration Windows SharePoint Foundation 2010 and Microsoft SharePoint Server 2010

CERN Document Server

Husman, Göran

2010-01-01

Complete coverage on the latest advances in SharePoint 2010 administration. SharePoint 2010 comprises an abundance of new features, and this book shows you how to take advantage of all SharePoint 2010's many improvements. Written by a four-time SharePoint MVP, Beginning SharePoint 2010 Administration begins with a comparison of SharePoint 2010 compared to the previous version and then examines the differences between WSS 4.0 and MSS 2010. Packed with step-by-step instructions, tips and tricks, and real-world examples, this book dives into the basics of how to install, manage, and administrate

Import/Export: Trafficking in Cross-Cultural Shakespearean Spaces

Directory of Open Access Journals (Sweden)

Desmet Christy

2017-09-01

Full Text Available This essay examines the phenomenon of cross-cultural Shakespearean “traffic” as an import/export “business” by analyzing the usefulness of the concept cross-cultural through a series of theoretical binaries: Global vs. Local Shakespeares, Glocal and Intercultural Shakespeare; and the very definition of space and place within the Shakespearean lexicon. The essay argues that theoretically, the opposition of global and local Shakespeares has a tendency to collapse, and both glocal and intercultural Shakespeares are the object of serious critique. However, the project of cross-cultural Shakespeare is sustained by the dialectic between memorialization and forgetting that attends all attempts to record these cross-cultural experiences. The meaning of cross-cultural Shakespeare lies in the interpreter’s agency.

Using Critical Cosmopolitanism to Globally Situate Multicultural Education in Teacher Preparation Courses

Science.gov (United States)

Byker, Erik Jon; Marquardt, Sheila K.

2016-01-01

Globally-minded teachers often beget globally-minded students. The same relationship seems to hold true for multiculturalism; teachers who are committed to multiculturalism often nudge students toward the same commitment. Global citizenship and multicultural education share a strong bond. Yet, in the field of social studies teacher preparation,…

The HydroServer Platform for Sharing Hydrologic Data

Science.gov (United States)

Tarboton, D. G.; Horsburgh, J. S.; Schreuders, K.; Maidment, D. R.; Zaslavsky, I.; Valentine, D. W.

2010-12-01

The CUAHSI Hydrologic Information System (HIS) is an internet based system that supports sharing of hydrologic data. HIS consists of databases connected using the Internet through Web services, as well as software for data discovery, access, and publication. The HIS system architecture is comprised of servers for publishing and sharing data, a centralized catalog to support cross server data discovery and a desktop client to access and analyze data. This paper focuses on HydroServer, the component developed for sharing and publishing space-time hydrologic datasets. A HydroServer is a computer server that contains a collection of databases, web services, tools, and software applications that allow data producers to store, publish, and manage the data from an experimental watershed or project site. HydroServer is designed to permit publication of data as part of a distributed national/international system, while still locally managing access to the data. We describe the HydroServer architecture and software stack, including tools for managing and publishing time series data for fixed point monitoring sites as well as spatially distributed, GIS datasets that describe a particular study area, watershed, or region. HydroServer adopts a standards based approach to data publication, relying on accepted and emerging standards for data storage and transfer. CUAHSI developed HydroServer code is free with community code development managed through the codeplex open source code repository and development system. There is some reliance on widely used commercial software for general purpose and standard data publication capability. The sharing of data in a common format is one way to stimulate interdisciplinary research and collaboration. It is anticipated that the growing, distributed network of HydroServers will facilitate cross-site comparisons and large scale studies that synthesize information from diverse settings, making the network as a whole greater than the sum of its

Radiative efficiencies and global warming potentials using theoretically determined absorption cross-sections for several hydrofluoroethers (HFEs) and hydrofluoropolyethers (HFPEs)

International Nuclear Information System (INIS)

Bravo, Ivan; Marston, George; Nutt, David R.; Shine, Keith P.

2011-01-01

Integrated infrared cross-sections and wavenumber positions for the vibrational modes of a range of hydrofluoroethers (HFEs) and hydrofluoropolyethers (HFPEs) have been calculated. Spectra were determined using a density functional method with an empirically derived correction for the wavenumbers of band positions. Radiative efficiencies (REs) were determined using the Pinnock et al. method and were used with atmospheric lifetimes from the literature to determine global warming potentials (GWPs). For the HFEs and the majority of the molecules in the HG series HFPEs, theoretically determined absorption cross-sections and REs lie within ca. 10% of those determined using measured spectra. For the larger molecules in the HG series and the HG' series of HFPEs, agreement is less good, with theoretical values for the integrated cross-sections being up to 35% higher than the experimental values; REs are up to 45% higher. Our method gives better results than previous theoretical approaches, because of the level of theory chosen and, for REs, because an empirical wavenumber correction derived for perfluorocarbons is effective in predicting the positions of C-F stretching frequencies at around 1250 cm -1 for the molecules considered here.

Cross-reactivity profiles of hybrid capture II, cobas, and APTIMA human papillomavirus assays

DEFF Research Database (Denmark)

Preisler, Sarah Nørgaard; Rebolj, Matejka; Ejegod, Ditte Møller

2016-01-01

evaluated to what extent these can be explained by cross-reactivity, i.e. positive test results without evidence of high-risk HPV genotypes. The patterns of cross-reactivity have been thoroughly studied for hybrid capture II (HC2) but not yet for newer HPV assays although the manufacturers claimed...... no or limited frequency of cross-reactivity. In this independent study we evaluated the frequency of cross-reactivity for HC2, cobas, and APTIMA assays. Methods Consecutive routine cervical screening samples from 5022 Danish women, including 2859 from women attending primary screening, were tested...... with normal cytology and positive high-risk HPV test results were invited for repeated testing in 18 months. Results Cross-reactivity to low-risk genotypes was detected in 109 (2.2 %) out of 5022 samples on HC2, 62 (1.2 %) on cobas, and 35 (0.7 %) on APTIMA with only 10 of the samples cross-reacting on all 3...

Transnational orientations in a global media landscape: Youth, media, war and conflict

Directory of Open Access Journals (Sweden)

Elisabeth Eide

2014-04-01

Full Text Available This article reflects on the role of media in the re-imagination and reproduction (reconstruction of Norwegian identities and communities with a particular focus on how young people within diasporas follow news on war and conflict in their (or their parents’ countries of origin. The research employs focus groups with young people from the Pakistani, Afghan, and Tamil Diasporas, and also online surveys. The three groups share the experience of trying to build a life in another country (Norway, while their family and friends in the “homeland” experience political violence and civil war. We identify a notable sense of frustration and skepticism towards Norwegian media. The informants actively use international media and media from the homeland, and often find these more reliable and providing more relevant information than Norwegian media. They also voice a strong critique of the ways in which the media react when “the others” are victims of violence, and several participants react negatively towards the neglect of positive reporting from their respective homelands, and to media hostility towards Muslims.

Introduction to Global Health Promotion.

Science.gov (United States)

Torres, Jennifer

2017-03-01

Global health education is becoming increasingly prominent in universities throughout the country especially in programs focused on health and behavioral sciences, law, economics, and political science. Introduction to Global Health Promotion is a book that can be used by both instructors and students in the field of global health. The book provides theories and models, human rights, and technology relevant to the field. In addition the book is designed to share best evidence for promoting health and reducing morbidity and mortality in a variety of areas. The book can be used by health educators, public health practitioners, professors, and students as a resource for research and practice in the field of health promotion and disease prevention.

Experience and Cultural Learning in Global Business Contexts

DEFF Research Database (Denmark)

Søderberg, Anne-Marie

2017-01-01

. Learners in today’s global business (school) world are more culturally diverse, and the potential of the increasing number of bi-cultural and bi-lingual students and managers as boundary-spanners must be considered. Recent empirical studies of face-to-face and virtual global collaboration show that cross...... divides. This chapter discusses a number of issues in relation to cultural learning processes in global business contexts: various concepts of learning, different approaches to cross-cultural competence training of future global leaders, and various learning contexts in management education and training......Globalization with increased mobility of the workforce and more frequent use of information and communication technologies means still more people must develop a deeper understanding of Cultural Others, a higher degree of cultural self-awareness and an ability to bridge across multiple cultural...

Crossed radio-immunoisoelectric focusing as a method of identifying isoallergens: identification of isoallergens in rat urine extracts

International Nuclear Information System (INIS)

Longbottom, J.L.

1984-01-01

A method of 2-dimensional radio-immunoelectrophoresis to detect directly the presence of 'isoallergens' in complex allergenic (skin test) extracts is described. This procedure, in which the components are separated by isoelectric focusing in agarose gel in the first dimension is therefore basically similar to that of crossed radio-immunoelectrophoresis, and hence has been termed crossed radio-immunoisoelectric focusing. The method has been applied to the allergens present in rat urine and has verified the presence of the cross-reacting α 2 -euglobulin and prealbumin components in (at least) 3 and 2 isoallergenic forms respectively. (Auth.)

Shared vs. Primary Epistemic Authority in Jaminjung/Ngaliwurru

Directory of Open Access Journals (Sweden)

Schultze-Berndt Eva

2017-10-01

Full Text Available This paper contributes to the typology of complex perspective markers by presenting an in-depth analysis of a system of epistemic authority marking which functionally overlaps with, but has no exact parallels in, similar systems attested cross-linguistically; it is also the first analysis of grammaticalised marking of epistemic authority in a language of Australia. Jaminjung/Ngaliwurru, a language of the Mirndi family, distinguishes between primary and shared epistemic authority by means of two non-obligatory clitics. By employing the first clitic, speakers claim privileged (asymmetrical access to evidence informing their utterance; the holder of epistemic primacy shifts to addressees in questions. The second marker, which is transparently related to a 1st+2nd person minimal pronoun, indicates shared (symmetrical epistemic access, but is further constrained in its distribution in that the evidence has to be accessible at the time of discourse and in that the encoded situation itself is not yet part of the common ground. In the light of the proposed analysis as well as cross-linguistic findings, it will be argued that epistemic authority markers more generally can be considered as part of a single functional domain with evidentials, and that this domain also includes egophoricity.

The emergence of global climate law

NARCIS (Netherlands)

Farber, D.A.; Peeters, Marjan; Farber, Daniel A.; Peeters, Marjan

2016-01-01

As the chapters in this Encyclopedia demonstrate, climate law is a dynamic and multidisciplinary field, implicating many diverse fields of law at all levels from municipal planning through multinational treaties. The outlines of an emerging global law can be discerned, including shared principles

Share and share alike? Social information and interaction style in coordination of shared use

NARCIS (Netherlands)

Niemantsverdriet, Karin; van de Werff, T.C.F.; van Essen, H.A.; Eggen, J.H.

2018-01-01

Interfaces are commonly designed from the perspective of individual users, even though most of the systems we use in everyday life are in fact shared. We argue that more attention is needed for system sharing, especially because interfaces are known to influence coordination of shared use. In this

LES-ODT Simulations of Turbulent Reacting Shear Layers

Science.gov (United States)

Hoffie, Andreas; Echekki, Tarek

2012-11-01

Large-eddy simulations (LES) combined with the one-dimensional turbulence (ODT) simulations of a spatially developing turbulent reacting shear layer with heat release and high Reynolds numbers were conducted and compared to results from direct numerical simulations (DNS) of the same configuration. The LES-ODT approach is based on LES solutions for momentum on a coarse grid and solutions for momentum and reactive scalars on a fine ODT grid, which is embedded in the LES computational domain. The shear layer is simulated with a single-step, second-order reaction with an Arrhenius reaction rate. The transport equations are solved using a low Mach number approximation. The LES-ODT simulations yield reasonably accurate predictions of turbulence and passive/reactive scalars' statistics compared to DNS results.

Fixed Access Network Sharing

Science.gov (United States)

Cornaglia, Bruno; Young, Gavin; Marchetta, Antonio

2015-12-01

Fixed broadband network deployments are moving inexorably to the use of Next Generation Access (NGA) technologies and architectures. These NGA deployments involve building fiber infrastructure increasingly closer to the customer in order to increase the proportion of fiber on the customer's access connection (Fibre-To-The-Home/Building/Door/Cabinet… i.e. FTTx). This increases the speed of services that can be sold and will be increasingly required to meet the demands of new generations of video services as we evolve from HDTV to "Ultra-HD TV" with 4k and 8k lines of video resolution. However, building fiber access networks is a costly endeavor. It requires significant capital in order to cover any significant geographic coverage. Hence many companies are forming partnerships and joint-ventures in order to share the NGA network construction costs. One form of such a partnership involves two companies agreeing to each build to cover a certain geographic area and then "cross-selling" NGA products to each other in order to access customers within their partner's footprint (NGA coverage area). This is tantamount to a bi-lateral wholesale partnership. The concept of Fixed Access Network Sharing (FANS) is to address the possibility of sharing infrastructure with a high degree of flexibility for all network operators involved. By providing greater configuration control over the NGA network infrastructure, the service provider has a greater ability to define the network and hence to define their product capabilities at the active layer. This gives the service provider partners greater product development autonomy plus the ability to differentiate from each other at the active network layer.

Involving Research Stakeholders in Developing Policy on Sharing Public Health Research Data in Kenya

Science.gov (United States)

Jao, Irene; Kombe, Francis; Mwalukore, Salim; Bull, Susan; Parker, Michael; Kamuya, Dorcas; Molyneux, Sassy

2015-01-01

Increased global sharing of public health research data has potential to advance scientific progress but may present challenges to the interests of research stakeholders, particularly in low-to-middle income countries. Policies for data sharing should be responsive to public views, but there is little evidence of the systematic study of these from low-income countries. This qualitative study explored views on fair data-sharing processes among 60 stakeholders in Kenya with varying research experience, using a deliberative approach. Stakeholders’ attitudes were informed by perceptions of benefit and concerns for research data sharing, including risks of stigmatization, loss of privacy, and undermining scientific careers and validity, reported in detail elsewhere. In this article, we discuss institutional trust-building processes seen as central to perceptions of fairness in sharing research data in this setting, including forms of community involvement, individual prior awareness and agreement to data sharing, independence and accountability of governance mechanisms, and operating under a national framework. PMID:26297748

Global Microbial Identifier

DEFF Research Database (Denmark)

Wielinga, Peter; Hendriksen, Rene S.; Aarestrup, Frank Møller

2017-01-01

) will likely also enable a much better understanding of the pathogenesis of the infection and the molecular basis of the host response to infection. But the full potential of these advances will only transpire if the data in this area become transferable and thereby comparable, preferably in open-source...... of microorganisms, for the identification of relevant genes and for the comparison of genomes to detect outbreaks and emerging pathogens. To harness the full potential of WGS, a shared global database of genomes linked to relevant metadata and the necessary software tools needs to be generated, hence the global...... microbial identifier (GMI) initiative. This tool will ideally be used in amongst others in the diagnosis of infectious diseases in humans and animals, in the identification of microorganisms in food and environment, and to track and trace microbial agents in all arenas globally. This will require...

Religious affiliation at time of death - Global estimates and projections.

Science.gov (United States)

Skirbekk, Vegard; Todd, Megan; Stonawski, Marcin

2018-03-01

Religious affiliation influences societal practices regarding death and dying, including palliative care, religiously acceptable health service procedures, funeral rites and beliefs about an afterlife. We aimed to estimate and project religious affiliation at the time of death globally, as this information has been lacking. We compiled data on demographic information and religious affiliation from more than 2500 surveys, registers and censuses covering 198 nations/territories. We present estimates of religious affiliation at the time of death as of 2010, projections up to and including 2060, taking into account trends in mortality, religious conversion, intergenerational transmission of religion, differential fertility, and gross migration flows, by age and sex. We find that Christianity continues to be the most common religion at death, although its share will fall from 37% to 31% of global deaths between 2010 and 2060. The share of individuals identifying as Muslim at the time of death increases from 21% to 24%. The share of religiously unaffiliated will peak at 17% in 2035 followed by a slight decline thereafter. In specific regions, such as Europe, the unaffiliated share will continue to rises from 14% to 21% throughout the period. Religious affiliation at the time of death is changing globally, with distinct regional patterns. This could affect spatial variation in healthcare and social customs relating to death and dying.

Detecting and Reacting to Change: The Effect of Exposure to Narrow Categorizations

Science.gov (United States)

Chakravarti, Amitav; Fang, Christina; Shapira, Zur

2011-01-01

The ability to detect a change, to accurately assess the magnitude of the change, and to react to that change in a commensurate fashion are of critical importance in many decision domains. Thus, it is important to understand the factors that systematically affect people's reactions to change. In this article we document a novel effect: Decision…

Crossing the Atlantic: Integrating Cross-Cultural Experiences into Undergraduate Business Courses Using Virtual Communities Technology

Science.gov (United States)