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Sample records for global optimization strategy

  1. Global optimization numerical strategies for rate-independent processes

    Benešová, Barbora

    2011-01-01

    Roč. 50, č. 2 (2011), s. 197-220 ISSN 0925-5001 R&D Projects: GA ČR GAP201/10/0357 Grant - others:GA MŠk(CZ) LC06052 Program:LC Institutional research plan: CEZ:AV0Z20760514 Keywords : rate-independent processes * numerical global optimization * energy estimates based algorithm Subject RIV: BA - General Mathematics Impact factor: 1.196, year: 2011 http://math.hnue.edu.vn/portal/rss.viewpage.php?id=0000037780&ap=L3BvcnRhbC9ncmFiYmVyLnBocD9jYXRpZD0xMDEyJnBhZ2U9Mg==

  2. Global Strategy

    Li, Peter Ping

    2013-01-01

    Global strategy differs from domestic strategy in terms of content and process as well as context and structure. The content of global strategy can contain five key elements, while the process of global strategy can have six major stages. These are expounded below. Global strategy is influenced...... by rich and complementary local contexts with diverse resource pools and game rules at the national level to form a broad ecosystem at the global level. Further, global strategy dictates the interaction or balance between different entry strategies at the levels of internal and external networks....

  3. A New Hybrid Whale Optimizer Algorithm with Mean Strategy of Grey Wolf Optimizer for Global Optimization

    Narinder Singh

    2018-03-01

    Full Text Available The quest for an efficient nature-inspired optimization technique has continued over the last few decades. In this paper, a hybrid nature-inspired optimization technique has been proposed. The hybrid algorithm has been constructed using Mean Grey Wolf Optimizer (MGWO and Whale Optimizer Algorithm (WOA. We have utilized the spiral equation of Whale Optimizer Algorithm for two procedures in the Hybrid Approach GWO (HAGWO algorithm: (i firstly, we used the spiral equation in Grey Wolf Optimizer algorithm for balance between the exploitation and the exploration process in the new hybrid approach; and (ii secondly, we also applied this equation in the whole population in order to refrain from the premature convergence and trapping in local minima. The feasibility and effectiveness of the hybrid algorithm have been tested by solving some standard benchmarks, XOR, Baloon, Iris, Breast Cancer, Welded Beam Design, Pressure Vessel Design problems and comparing the results with those obtained through other metaheuristics. The solutions prove that the newly existing hybrid variant has higher stronger stability, faster convergence rate and computational accuracy than other nature-inspired metaheuristics on the maximum number of problems and can successfully resolve the function of constrained nonlinear optimization in reality.

  4. A Guiding Evolutionary Algorithm with Greedy Strategy for Global Optimization Problems

    Leilei Cao

    2016-01-01

    Full Text Available A Guiding Evolutionary Algorithm (GEA with greedy strategy for global optimization problems is proposed. Inspired by Particle Swarm Optimization, the Genetic Algorithm, and the Bat Algorithm, the GEA was designed to retain some advantages of each method while avoiding some disadvantages. In contrast to the usual Genetic Algorithm, each individual in GEA is crossed with the current global best one instead of a randomly selected individual. The current best individual served as a guide to attract offspring to its region of genotype space. Mutation was added to offspring according to a dynamic mutation probability. To increase the capability of exploitation, a local search mechanism was applied to new individuals according to a dynamic probability of local search. Experimental results show that GEA outperformed the other three typical global optimization algorithms with which it was compared.

  5. Economic optimization of a global strategy to address the pandemic threat.

    Pike, Jamison; Bogich, Tiffany; Elwood, Sarah; Finnoff, David C; Daszak, Peter

    2014-12-30

    Emerging pandemics threaten global health and economies and are increasing in frequency. Globally coordinated strategies to combat pandemics, similar to current strategies that address climate change, are largely adaptive, in that they attempt to reduce the impact of a pathogen after it has emerged. However, like climate change, mitigation strategies have been developed that include programs to reduce the underlying drivers of pandemics, particularly animal-to-human disease transmission. Here, we use real options economic modeling of current globally coordinated adaptation strategies for pandemic prevention. We show that they would be optimally implemented within 27 y to reduce the annual rise of emerging infectious disease events by 50% at an estimated one-time cost of approximately $343.7 billion. We then analyze World Bank data on multilateral "One Health" pandemic mitigation programs. We find that, because most pandemics have animal origins, mitigation is a more cost-effective policy than business-as-usual adaptation programs, saving between $344.0.7 billion and $360.3 billion over the next 100 y if implemented today. We conclude that globally coordinated pandemic prevention policies need to be enacted urgently to be optimally effective and that strategies to mitigate pandemics by reducing the impact of their underlying drivers are likely to be more effective than business as usual.

  6. Economic optimization of a global strategy to address the pandemic threat

    Pike, Jamison; Bogich, Tiffany; Elwood, Sarah; Finnoff, David C.; Daszak, Peter

    2014-01-01

    Emerging pandemics threaten global health and economies and are increasing in frequency. Globally coordinated strategies to combat pandemics, similar to current strategies that address climate change, are largely adaptive, in that they attempt to reduce the impact of a pathogen after it has emerged. However, like climate change, mitigation strategies have been developed that include programs to reduce the underlying drivers of pandemics, particularly animal-to-human disease transmission. Here, we use real options economic modeling of current globally coordinated adaptation strategies for pandemic prevention. We show that they would be optimally implemented within 27 y to reduce the annual rise of emerging infectious disease events by 50% at an estimated one-time cost of approximately $343.7 billion. We then analyze World Bank data on multilateral “One Health” pandemic mitigation programs. We find that, because most pandemics have animal origins, mitigation is a more cost-effective policy than business-as-usual adaptation programs, saving between $344.0.7 billion and $360.3 billion over the next 100 y if implemented today. We conclude that globally coordinated pandemic prevention policies need to be enacted urgently to be optimally effective and that strategies to mitigate pandemics by reducing the impact of their underlying drivers are likely to be more effective than business as usual. PMID:25512538

  7. Stochastic and global optimization

    Dzemyda, Gintautas; Šaltenis, Vydūnas; Zhilinskas, A; Mockus, Jonas

    2002-01-01

    ... and Effectiveness of Controlled Random Search E. M. T. Hendrix, P. M. Ortigosa and I. García 129 9. Discrete Backtracking Adaptive Search for Global Optimization B. P. Kristinsdottir, Z. B. Zabinsky and...

  8. Subdivision, Sampling, and Initialization Strategies for Simplical Branch and Bound in Global Optimization

    Clausen, Jens; Zilinskas, A,

    2002-01-01

    We consider the problem of optimizing a Lipshitzian function. The branch and bound technique is a well-known solution method, and the key components for this are the subdivision scheme, the bound calculation scheme, and the initialization. For Lipschitzian optimization, the bound calculations are...

  9. European strategy/global strategy

    Testore, R. [FIAT Auto S.p.A., Turin (Italy)

    1998-08-01

    In order to be `global`, a carmaker has to satisfy three main criteria: a global customer service, a global market presence, a global respect for the environment. Just in a word, the automotive industry needs to develop - and has indeed already launched - a process of global re-engineering of its: product, processes, and market. The product is not simply a `car`, but a global mobility service. This is what an increasingly diversified clientele is demanding in order to meet its particular mobility needs in terms of comfort and safety, in a way that does not damage the environment and at welldefined, competitive costs. The process is not just a matter of the way we design, manufacture and distribute our product. We have to re-design our entire corporate profile, redefine the parameters of our specific strategic mission, identifying the levels of control and our core business in a way that is consistent with our particular history, market positioning and growth targets. The market is no longer hard set, but is globally diversified, ready to expand into important niches and to meet the personalized needs of specific users: from VIPs to the elderly or the disables, and so on. (orig.)

  10. Optimal GENCO bidding strategy

    Gao, Feng

    Electricity industries worldwide are undergoing a period of profound upheaval. The conventional vertically integrated mechanism is being replaced by a competitive market environment. Generation companies have incentives to apply novel technologies to lower production costs, for example: Combined Cycle units. Economic dispatch with Combined Cycle units becomes a non-convex optimization problem, which is difficult if not impossible to solve by conventional methods. Several techniques are proposed here: Mixed Integer Linear Programming, a hybrid method, as well as Evolutionary Algorithms. Evolutionary Algorithms share a common mechanism, stochastic searching per generation. The stochastic property makes evolutionary algorithms robust and adaptive enough to solve a non-convex optimization problem. This research implements GA, EP, and PS algorithms for economic dispatch with Combined Cycle units, and makes a comparison with classical Mixed Integer Linear Programming. The electricity market equilibrium model not only helps Independent System Operator/Regulator analyze market performance and market power, but also provides Market Participants the ability to build optimal bidding strategies based on Microeconomics analysis. Supply Function Equilibrium (SFE) is attractive compared to traditional models. This research identifies a proper SFE model, which can be applied to a multiple period situation. The equilibrium condition using discrete time optimal control is then developed for fuel resource constraints. Finally, the research discusses the issues of multiple equilibria and mixed strategies, which are caused by the transmission network. Additionally, an advantage of the proposed model for merchant transmission planning is discussed. A market simulator is a valuable training and evaluation tool to assist sellers, buyers, and regulators to understand market performance and make better decisions. A traditional optimization model may not be enough to consider the distributed

  11. Optimal intermittent search strategies

    Rojo, F; Budde, C E; Wio, H S

    2009-01-01

    We study the search kinetics of a single fixed target by a set of searchers performing an intermittent random walk, jumping between different internal states. Exploiting concepts of multi-state and continuous-time random walks we have calculated the survival probability of a target up to time t, and have 'optimized' (minimized) it with regard to the transition probability among internal states. Our model shows that intermittent strategies always improve target detection, even for simple diffusion states of motion

  12. Enhancing Artificial Bee Colony Algorithm with Self-Adaptive Searching Strategy and Artificial Immune Network Operators for Global Optimization

    Tinggui Chen

    2014-01-01

    Full Text Available Artificial bee colony (ABC algorithm, inspired by the intelligent foraging behavior of honey bees, was proposed by Karaboga. It has been shown to be superior to some conventional intelligent algorithms such as genetic algorithm (GA, artificial colony optimization (ACO, and particle swarm optimization (PSO. However, the ABC still has some limitations. For example, ABC can easily get trapped in the local optimum when handing in functions that have a narrow curving valley, a high eccentric ellipse, or complex multimodal functions. As a result, we proposed an enhanced ABC algorithm called EABC by introducing self-adaptive searching strategy and artificial immune network operators to improve the exploitation and exploration. The simulation results tested on a suite of unimodal or multimodal benchmark functions illustrate that the EABC algorithm outperforms ACO, PSO, and the basic ABC in most of the experiments.

  13. Global Optimal Energy Management Strategy Research for a Plug-In Series-Parallel Hybrid Electric Bus by Using Dynamic Programming

    Hongwen He

    2013-01-01

    Full Text Available Energy management strategy influences the power performance and fuel economy of plug-in hybrid electric vehicles greatly. To explore the fuel-saving potential of a plug-in hybrid electric bus (PHEB, this paper searched the global optimal energy management strategy using dynamic programming (DP algorithm. Firstly, the simplified backward model of the PHEB was built which is necessary for DP algorithm. Then the torque and speed of engine and the torque of motor were selected as the control variables, and the battery state of charge (SOC was selected as the state variables. The DP solution procedure was listed, and the way was presented to find all possible control variables at every state of each stage in detail. Finally, the appropriate SOC increment is determined after quantizing the state variables, and then the optimal control of long driving distance of a specific driving cycle is replaced with the optimal control of one driving cycle, which reduces the computational time significantly and keeps the precision at the same time. The simulation results show that the fuel economy of the PEHB with the optimal energy management strategy is improved by 53.7% compared with that of the conventional bus, which can be a benchmark for the assessment of other control strategies.

  14. Optimal fuel inventory strategies

    Caspary, P.J.; Hollibaugh, J.B.; Licklider, P.L.; Patel, K.P.

    1990-01-01

    In an effort to maintain their competitive edge, most utilities are reevaluating many of their conventional practices and policies in an effort to further minimize customer revenue requirements without sacrificing system reliability. Over the past several years, Illinois Power has been rethinking its traditional fuel inventory strategies, recognizing that coal supplies are competitive and plentiful and that carrying charges on inventory are expensive. To help the Company achieve one of its strategic corporate goals, an optimal fuel inventory study was performed for its five major coal-fired generating stations. The purpose of this paper is to briefly describe Illinois Power's system and past practices concerning coal inventories, highlight the analytical process behind the optimal fuel inventory study, and discuss some of the recent experiences affecting coal deliveries and economic dispatch

  15. Optimal intermittent search strategies

    Rojo, F; Budde, C E [FaMAF, Universidad Nacional de Cordoba, Ciudad Universitaria, X5000HUA Cordoba (Argentina); Wio, H S [Instituto de Fisica de Cantabria, Universidad de Cantabria and CSIC E-39005 Santander (Spain)

    2009-03-27

    We study the search kinetics of a single fixed target by a set of searchers performing an intermittent random walk, jumping between different internal states. Exploiting concepts of multi-state and continuous-time random walks we have calculated the survival probability of a target up to time t, and have 'optimized' (minimized) it with regard to the transition probability among internal states. Our model shows that intermittent strategies always improve target detection, even for simple diffusion states of motion.

  16. Global optimization and simulated annealing

    Dekkers, A.; Aarts, E.H.L.

    1988-01-01

    In this paper we are concerned with global optimization, which can be defined as the problem of finding points on a bounded subset of Rn in which some real valued functionf assumes its optimal (i.e. maximal or minimal) value. We present a stochastic approach which is based on the simulated annealing

  17. Convex analysis and global optimization

    Tuy, Hoang

    2016-01-01

    This book presents state-of-the-art results and methodologies in modern global optimization, and has been a staple reference for researchers, engineers, advanced students (also in applied mathematics), and practitioners in various fields of engineering. The second edition has been brought up to date and continues to develop a coherent and rigorous theory of deterministic global optimization, highlighting the essential role of convex analysis. The text has been revised and expanded to meet the needs of research, education, and applications for many years to come. Updates for this new edition include: · Discussion of modern approaches to minimax, fixed point, and equilibrium theorems, and to nonconvex optimization; · Increased focus on dealing more efficiently with ill-posed problems of global optimization, particularly those with hard constraints;

  18. A Direct Search Algorithm for Global Optimization

    Enrique Baeyens

    2016-06-01

    Full Text Available A direct search algorithm is proposed for minimizing an arbitrary real valued function. The algorithm uses a new function transformation and three simplex-based operations. The function transformation provides global exploration features, while the simplex-based operations guarantees the termination of the algorithm and provides global convergence to a stationary point if the cost function is differentiable and its gradient is Lipschitz continuous. The algorithm’s performance has been extensively tested using benchmark functions and compared to some well-known global optimization algorithms. The results of the computational study show that the algorithm combines both simplicity and efficiency and is competitive with the heuristics-based strategies presently used for global optimization.

  19. Military Strategy of Global Jihad

    Zabel, Sarah E

    2007-01-01

    .... The 9/11 attacks set this plan in motion. In the years leading up to and following the 9/11 attacks, global jihadis have written copiously on their military strategy for creating an Islamic state...

  20. Implementing optimal thinning strategies

    Kurt H. Riitters; J. Douglas Brodie

    1984-01-01

    Optimal thinning regimes for achieving several management objectives were derived from two stand-growth simulators by dynamic programming. Residual mean tree volumes were then plotted against stand density management diagrams. The results supported the use of density management diagrams for comparing, checking, and implementing the results of optimization analyses....

  1. Optimizing decommissioning strategies

    Passant, F.H.

    1993-01-01

    Many different approaches can be considered for achieving satisfactory decommissioning of nuclear installations. These can embrace several different engineering actions at several stages, with time variations between the stages. Multi-attribute analysis can be used to help in the decision making process and to establish the optimum strategy. It has been used in the Usa and the UK to help in selecting preferred sites for radioactive waste repositories, and also in UK to help with the choice of preferred sites for locating PWR stations, and in selecting optimum decommissioning strategies

  2. Global optimization and sensitivity analysis

    Cacuci, D.G.

    1990-01-01

    A new direction for the analysis of nonlinear models of nuclear systems is suggested to overcome fundamental limitations of sensitivity analysis and optimization methods currently prevalent in nuclear engineering usage. This direction is toward a global analysis of the behavior of the respective system as its design parameters are allowed to vary over their respective design ranges. Presented is a methodology for global analysis that unifies and extends the current scopes of sensitivity analysis and optimization by identifying all the critical points (maxima, minima) and solution bifurcation points together with corresponding sensitivities at any design point of interest. The potential applicability of this methodology is illustrated with test problems involving multiple critical points and bifurcations and comprising both equality and inequality constraints

  3. Optimal coal import strategy

    Chen, C.Y.; Shih, L.H.

    1992-01-01

    Recently, the main power company in Taiwan has shifted the primary energy resource from oil to coal and tried to diversify the coal supply from various sources. The company wants to have the imported coal meet the environmental standards and operation requirements as well as to have high heating value. In order to achieve these objectives, establishment of a coal blending system for Taiwan is necessary. A mathematical model using mixed integer programming technique is used to model the import strategy and the blending system. 6 refs., 1 tab

  4. Switching strategies to optimize search

    Shlesinger, Michael F

    2016-01-01

    Search strategies are explored when the search time is fixed, success is probabilistic and the estimate for success can diminish with time if there is not a successful result. Under the time constraint the problem is to find the optimal time to switch a search strategy or search location. Several variables are taken into account, including cost, gain, rate of success if a target is present and the probability that a target is present. (paper: interdisciplinary statistical mechanics)

  5. Optimal Strategy and Business Models

    Johnson, Peter; Foss, Nicolai Juul

    2016-01-01

    This study picks up on earlier suggestions that control theory may further the study of strategy. Strategy can be formally interpreted as an idealized path optimizing heterogeneous resource deployment to produce maximum financial gain. Using standard matrix methods to describe the firm Hamiltonia...... variable of firm path, suggesting in turn that the firm's business model is the codification of the application of investment resources used to control the strategic path of value realization....

  6. Global power: Markets and strategies

    Poirer, J.L.

    1998-01-01

    The author will first present an updated view of the global power market activity, including opportunities in power generation, transmission and distribution. This will include a review of the trends in closings and transaction flowed by type of activity and geographic area. Estimates will be based on Hagler Bailly's comprehensive database on global power transactions and project announcements. The firm has also worked with dozens of global power companies since 1990. Second, the author will review trends in terms of regulatory changes, project cost trends, developers' project experiences, and financing issues. This systematic review will be the foundation for projection of future market activity (e.g., number of closing by type of project through 2000). A forecast of future greenfield and privatization activity will be provided and the key markets will be highlighted. Third, the author will present an updated view of the competition in the global power market (including the various types of competitors and changes in their respective market posture). Finally, the author will discuss the various types of strategies and business models that are followed by key global power players

  7. Mixed integer evolution strategies for parameter optimization.

    Li, Rui; Emmerich, Michael T M; Eggermont, Jeroen; Bäck, Thomas; Schütz, M; Dijkstra, J; Reiber, J H C

    2013-01-01

    Evolution strategies (ESs) are powerful probabilistic search and optimization algorithms gleaned from biological evolution theory. They have been successfully applied to a wide range of real world applications. The modern ESs are mainly designed for solving continuous parameter optimization problems. Their ability to adapt the parameters of the multivariate normal distribution used for mutation during the optimization run makes them well suited for this domain. In this article we describe and study mixed integer evolution strategies (MIES), which are natural extensions of ES for mixed integer optimization problems. MIES can deal with parameter vectors consisting not only of continuous variables but also with nominal discrete and integer variables. Following the design principles of the canonical evolution strategies, they use specialized mutation operators tailored for the aforementioned mixed parameter classes. For each type of variable, the choice of mutation operators is governed by a natural metric for this variable type, maximal entropy, and symmetry considerations. All distributions used for mutation can be controlled in their shape by means of scaling parameters, allowing self-adaptation to be implemented. After introducing and motivating the conceptual design of the MIES, we study the optimality of the self-adaptation of step sizes and mutation rates on a generalized (weighted) sphere model. Moreover, we prove global convergence of the MIES on a very general class of problems. The remainder of the article is devoted to performance studies on artificial landscapes (barrier functions and mixed integer NK landscapes), and a case study in the optimization of medical image analysis systems. In addition, we show that with proper constraint handling techniques, MIES can also be applied to classical mixed integer nonlinear programming problems.

  8. Essays and surveys in global optimization

    Audet, Charles; Savard, Giles

    2005-01-01

    Global optimization aims at solving the most general problems of deterministic mathematical programming. In addition, once the solutions are found, this methodology is also expected to prove their optimality. With these difficulties in mind, global optimization is becoming an increasingly powerful and important methodology. This book is the most recent examination of its mathematical capability, power, and wide ranging solutions to many fields in the applied sciences.

  9. The Strategy - Ending Globalization Disorders

    Yunus Lubega Butanaziba

    2010-12-01

    Full Text Available Scientifically, globalization is a pure-form or model that refers to a condition whereby a dominant state unilaterally or multilaterally maintains a balance of power to fail member states in the international system it dominates. Globalization can be implemented exclusively or inclusively under blocs (regional or International Governmental Organizations (IGOs as means of the balance of power for the failure of states. This is the theme that this article pursues to objectively examine the current globalization regime as the function of two arms of the balance of power applied to fail states in the international system. One arm of the current globalization regime applies interest-lending of the Bretton Woods institutions namely, International Bank for Reconstruction (IBRD/World Bank and International Monetary Fund (IMF. The other arm uses the strategy of resource wars. The problem is that interest charges of the World Bank and IMF have failed to cause real domestic growth in 185 states since the initial Ten/Five-year Development Plans, 1946/51-56. This is seen in the domestic and foreign debt burdens arising out of loan interests of the IBRD/World Bank and IMF. There have been more than 136 resource wars that have caused over250 million deaths (market value loss of over USD 500 trillion in the period 1946 to date. The unit of analysis of the paper is that the previous and current strategies of globalization have been illegitimate, severely violated fundamental human right, contravened business ethics and caused the failure states. Thus, the Bretton Woods system has not, and will not as it stands, benefit USA and her allied member states and the Third World inclusive.Legally and morally, Latin American states who signed the Bretton Woods Agreements in 1944 were not in-due-form: African, Asian and Eastern European states were not represented; and given the most compelling fact that others from Europe (e.g. Germany and Japan agreed in the unique

  10. Strategi Pemasaran Global di Pasar Indonesia

    Freddy Simbolon

    2013-05-01

    Full Text Available Globalization is a new challenge for companies in the implementation of marketing strategy. Due to globalization, companies are required to compete with world class companies that have large capital and higher quality products. Indonesia currently becomes the market target for global companies to enjoy huge profits, while the Indonesian companies lost the competition. This study aims to obtain global marketing strategy for Indonesian companies in Indonesian market. Research method used is descriptive analisys. Merger between adaptation of marketing strategies and standard marketing strategy is appropriate strategy in Indonesian market.

  11. Introduction to Nonlinear and Global Optimization

    Hendrix, E.M.T.; Tóth, B.

    2010-01-01

    This self-contained text provides a solid introduction to global and nonlinear optimization, providing students of mathematics and interdisciplinary sciences with a strong foundation in applied optimization techniques. The book offers a unique hands-on and critical approach to applied optimization

  12. Stochastic global optimization as a filtering problem

    Stinis, Panos

    2012-01-01

    We present a reformulation of stochastic global optimization as a filtering problem. The motivation behind this reformulation comes from the fact that for many optimization problems we cannot evaluate exactly the objective function to be optimized. Similarly, we may not be able to evaluate exactly the functions involved in iterative optimization algorithms. For example, we may only have access to noisy measurements of the functions or statistical estimates provided through Monte Carlo sampling. This makes iterative optimization algorithms behave like stochastic maps. Naive global optimization amounts to evolving a collection of realizations of this stochastic map and picking the realization with the best properties. This motivates the use of filtering techniques to allow focusing on realizations that are more promising than others. In particular, we present a filtering reformulation of global optimization in terms of a special case of sequential importance sampling methods called particle filters. The increasing popularity of particle filters is based on the simplicity of their implementation and their flexibility. We utilize the flexibility of particle filters to construct a stochastic global optimization algorithm which can converge to the optimal solution appreciably faster than naive global optimization. Several examples of parametric exponential density estimation are provided to demonstrate the efficiency of the approach.

  13. Advances in stochastic and deterministic global optimization

    Zhigljavsky, Anatoly; Žilinskas, Julius

    2016-01-01

    Current research results in stochastic and deterministic global optimization including single and multiple objectives are explored and presented in this book by leading specialists from various fields. Contributions include applications to multidimensional data visualization, regression, survey calibration, inventory management, timetabling, chemical engineering, energy systems, and competitive facility location. Graduate students, researchers, and scientists in computer science, numerical analysis, optimization, and applied mathematics will be fascinated by the theoretical, computational, and application-oriented aspects of stochastic and deterministic global optimization explored in this book. This volume is dedicated to the 70th birthday of Antanas Žilinskas who is a leading world expert in global optimization. Professor Žilinskas's research has concentrated on studying models for the objective function, the development and implementation of efficient algorithms for global optimization with single and mu...

  14. Global strategies to prevent chronic diseases1

    Nicky

    leading global causes of death and disability, are ... global strategies for the prevention and control of chronic ... Preventing Chronic Diseases: A Vital Investment, will ..... Millennium Development Goals for Health In Europe and Central Asia.

  15. Evolution strategies for robust optimization

    Kruisselbrink, Johannes Willem

    2012-01-01

    Real-world (black-box) optimization problems often involve various types of uncertainties and noise emerging in different parts of the optimization problem. When this is not accounted for, optimization may fail or may yield solutions that are optimal in the classical strict notion of optimality, but

  16. On the efficiency of chaos optimization algorithms for global optimization

    Yang Dixiong; Li Gang; Cheng Gengdong

    2007-01-01

    Chaos optimization algorithms as a novel method of global optimization have attracted much attention, which were all based on Logistic map. However, we have noticed that the probability density function of the chaotic sequences derived from Logistic map is a Chebyshev-type one, which may affect the global searching capacity and computational efficiency of chaos optimization algorithms considerably. Considering the statistical property of the chaotic sequences of Logistic map and Kent map, the improved hybrid chaos-BFGS optimization algorithm and the Kent map based hybrid chaos-BFGS algorithm are proposed. Five typical nonlinear functions with multimodal characteristic are tested to compare the performance of five hybrid optimization algorithms, which are the conventional Logistic map based chaos-BFGS algorithm, improved Logistic map based chaos-BFGS algorithm, Kent map based chaos-BFGS algorithm, Monte Carlo-BFGS algorithm, mesh-BFGS algorithm. The computational performance of the five algorithms is compared, and the numerical results make us question the high efficiency of the chaos optimization algorithms claimed in some references. It is concluded that the efficiency of the hybrid optimization algorithms is influenced by the statistical property of chaotic/stochastic sequences generated from chaotic/stochastic algorithms, and the location of the global optimum of nonlinear functions. In addition, it is inappropriate to advocate the high efficiency of the global optimization algorithms only depending on several numerical examples of low-dimensional functions

  17. On benchmarking Stochastic Global Optimization Algorithms

    Hendrix, E.M.T.; Lancinskas, A.

    2015-01-01

    A multitude of heuristic stochastic optimization algorithms have been described in literature to obtain good solutions of the box-constrained global optimization problem often with a limit on the number of used function evaluations. In the larger question of which algorithms behave well on which

  18. Optimal beneficiation of global resources

    Aloisi de Larderel, J. (Industry and Environment Office, Paris (France). United Nations Environment Programme)

    1989-01-01

    The growth of the world's population and related human activities are clearly leaving major effects on the environment and on the level of use of natural resources: forests are disappearing, air pollution is leading to acid rains, changes are occuring in the atmospheric ozone and global climate, more and more people lack access to reasonable safe supplies of water, soil pollution is becoming a problem, mineral and energy resources are increasingly being used. Producing more with less, producing more, polluting less, these are basic challenges that the world now faces. Low- and non-waste technologies are certainly one of the keys to those challenges.

  19. Corporate Strategies in Global Investment Business

    Tetiana Frolova

    2012-02-01

    Full Text Available The article deals with topical issues of the development of corporate strategies for businesses. We proposed the classification and defined the ways to implement corporate strategies. We also analysed the current trends in the development of global corporate strategies mainly implemented through mergers and acquisitions.

  20. Military Strategy of Global Jihad

    Zabel, Sarah E

    2007-01-01

    .... Global jihadis have spent more than 40 years refining their philosophy, gaining experience, building their organization, and developing plans to re-establish what they see as the only true Islamic state on earth...

  1. A global strategy for labor.

    Faux, Jeff

    2002-01-01

    The rules of the global market were established to protect the interests of investors at the expense of workers and they shift benefits to investors, costs to workers. Globalization is measured by the interests of investors. But 20 years of investor protectionism show that growth has slowed and equality has gotten worse. The purpose of neo-liberal policies has been to discipline labor to free capital from having to bargain with workers over gains from rising productivity. But such bargaining is the essence of a democratic market. Uncontrolled globalization puts government's domestic policies on the side of capital. In an economy whose growth depends on foreign markets, rising domestic wages make it harder to compete internationally. There has been a general deterioration of labor's position relative to capital's. A global marketplace implies a global politics, and the real work happens when representatives of multi-national business privately negotiate the rules. Labor must change the framework in which the investor class pursues its interest across borders, while workers are constricted by borders. Labor unions are critical; they can deny the human resource necessary for profits. The strike is the ultimate threat to investors. One solution: a "grand bargain" linking development with broadly increased living standards connected to planning for sustainable development to create a global social contract. Workers have advantages: they are the majority and they are indispensable.

  2. Evolutionary global optimization, manifolds and applications

    Aguiar e Oliveira Junior, Hime

    2016-01-01

    This book presents powerful techniques for solving global optimization problems on manifolds by means of evolutionary algorithms, and shows in practice how these techniques can be applied to solve real-world problems. It describes recent findings and well-known key facts in general and differential topology, revisiting them all in the context of application to current optimization problems. Special emphasis is put on game theory problems. Here, these problems are reformulated as constrained global optimization tasks and solved with the help of Fuzzy ASA. In addition, more abstract examples, including minimizations of well-known functions, are also included. Although the Fuzzy ASA approach has been chosen as the main optimizing paradigm, the book suggests that other metaheuristic methods could be used as well. Some of them are introduced, together with their advantages and disadvantages. Readers should possess some knowledge of linear algebra, and of basic concepts of numerical analysis and probability theory....

  3. Deterministic global optimization an introduction to the diagonal approach

    Sergeyev, Yaroslav D

    2017-01-01

    This book begins with a concentrated introduction into deterministic global optimization and moves forward to present new original results from the authors who are well known experts in the field. Multiextremal continuous problems that have an unknown structure with Lipschitz objective functions and functions having the first Lipschitz derivatives defined over hyperintervals are examined. A class of algorithms using several Lipschitz constants is introduced which has its origins in the DIRECT (DIviding RECTangles) method. This new class is based on an efficient strategy that is applied for the search domain partitioning. In addition a survey on derivative free methods and methods using the first derivatives is given for both one-dimensional and multi-dimensional cases. Non-smooth and smooth minorants and acceleration techniques that can speed up several classes of global optimization methods with examples of applications and problems arising in numerical testing of global optimization algorithms are discussed...

  4. Global optimization methods for engineering design

    Arora, Jasbir S.

    1990-01-01

    The problem is to find a global minimum for the Problem P. Necessary and sufficient conditions are available for local optimality. However, global solution can be assured only under the assumption of convexity of the problem. If the constraint set S is compact and the cost function is continuous on it, existence of a global minimum is guaranteed. However, in view of the fact that no global optimality conditions are available, a global solution can be found only by an exhaustive search to satisfy Inequality. The exhaustive search can be organized in such a way that the entire design space need not be searched for the solution. This way the computational burden is reduced somewhat. It is concluded that zooming algorithm for global optimizations appears to be a good alternative to stochastic methods. More testing is needed; a general, robust, and efficient local minimizer is required. IDESIGN was used in all numerical calculations which is based on a sequential quadratic programming algorithm, and since feasible set keeps on shrinking, a good algorithm to find an initial feasible point is required. Such algorithms need to be developed and evaluated.

  5. Conference on Convex Analysis and Global Optimization

    Pardalos, Panos

    2001-01-01

    There has been much recent progress in global optimization algo­ rithms for nonconvex continuous and discrete problems from both a theoretical and a practical perspective. Convex analysis plays a fun­ damental role in the analysis and development of global optimization algorithms. This is due essentially to the fact that virtually all noncon­ vex optimization problems can be described using differences of convex functions and differences of convex sets. A conference on Convex Analysis and Global Optimization was held during June 5 -9, 2000 at Pythagorion, Samos, Greece. The conference was honoring the memory of C. Caratheodory (1873-1950) and was en­ dorsed by the Mathematical Programming Society (MPS) and by the Society for Industrial and Applied Mathematics (SIAM) Activity Group in Optimization. The conference was sponsored by the European Union (through the EPEAEK program), the Department of Mathematics of the Aegean University and the Center for Applied Optimization of the University of Florida, by th...

  6. Determining an optimal supply chain strategy

    Intaher M. Ambe

    2012-11-01

    Full Text Available In today’s business environment, many companies want to become efficient and flexible, but have struggled, in part, because they have not been able to formulate optimal supply chain strategies. Often this is as a result of insufficient knowledge about the costs involved in maintaining supply chains and the impact of the supply chain on their operations. Hence, these companies find it difficult to manufacture at a competitive cost and respond quickly and reliably to market demand. Mismatched strategies are the root cause of the problems that plague supply chains, and supply-chain strategies based on a one-size-fits-all strategy often fail. The purpose of this article is to suggest instruments to determine an optimal supply chain strategy. This article, which is conceptual in nature, provides a review of current supply chain strategies and suggests a framework for determining an optimal strategy.

  7. A Unified Differential Evolution Algorithm for Global Optimization

    Qiang, Ji; Mitchell, Chad

    2014-06-24

    Abstract?In this paper, we propose a new unified differential evolution (uDE) algorithm for single objective global optimization. Instead of selecting among multiple mutation strategies as in the conventional differential evolution algorithm, this algorithm employs a single equation as the mutation strategy. It has the virtue of mathematical simplicity and also provides users the flexbility for broader exploration of different mutation strategies. Numerical tests using twelve basic unimodal and multimodal functions show promising performance of the proposed algorithm in comparison to convential differential evolution algorithms.

  8. Global Supply-Chain Strategy And Global Competitiveness

    Asghar Sabbaghi; Navid Sabbaghi

    2011-01-01

    The purpose of this study is to provide an analysis of global supply chain in a broader context that encompasses not only the producing company, but suppliers and customers.The theme of this study is to identify global sourcing and selling options, to enhance customer service and value added, to optimize inventory performance, to reduce total delivered costs and lead times, to achieve lower break-even costs, and to improve operational flexibility, customization and partner relations. In this ...

  9. Optimal management strategies in variable environments: Stochastic optimal control methods

    Williams, B.K.

    1985-01-01

    Dynamic optimization was used to investigate the optimal defoliation of salt desert shrubs in north-western Utah. Management was formulated in the context of optimal stochastic control theory, with objective functions composed of discounted or time-averaged biomass yields. Climatic variability and community patterns of salt desert shrublands make the application of stochastic optimal control both feasible and necessary. A primary production model was used to simulate shrub responses and harvest yields under a variety of climatic regimes and defoliation patterns. The simulation results then were used in an optimization model to determine optimal defoliation strategies. The latter model encodes an algorithm for finite state, finite action, infinite discrete time horizon Markov decision processes. Three questions were addressed: (i) What effect do changes in weather patterns have on optimal management strategies? (ii) What effect does the discounting of future returns have? (iii) How do the optimal strategies perform relative to certain fixed defoliation strategies? An analysis was performed for the three shrub species, winterfat (Ceratoides lanata), shadscale (Atriplex confertifolia) and big sagebrush (Artemisia tridentata). In general, the results indicate substantial differences among species in optimal control strategies, which are associated with differences in physiological and morphological characteristics. Optimal policies for big sagebrush varied less with variation in climate, reserve levels and discount rates than did either shadscale or winterfat. This was attributed primarily to the overwintering of photosynthetically active tissue and to metabolic activity early in the growing season. Optimal defoliation of shadscale and winterfat generally was more responsive to differences in plant vigor and climate, reflecting the sensitivity of these species to utilization and replenishment of carbohydrate reserves. Similarities could be seen in the influence of both

  10. two strategies to be integrated into globalization

    Alvarado, Fernando

    2011-01-01

    The present thesis work intends to investigate internal and external factors determining the type of strategy of foreign policy used by Argentina and Chile in order to be part of globalization. In both cases, it is a strategy where the emphasis on the management of foreign policy, more economic than political, prevails. However, under the same external context and similar formal institutional frameworks, the main difference of both strategies may be found in the conceptual approach, which is ...

  11. A Novel Particle Swarm Optimization Algorithm for Global Optimization.

    Wang, Chun-Feng; Liu, Kui

    2016-01-01

    Particle Swarm Optimization (PSO) is a recently developed optimization method, which has attracted interest of researchers in various areas due to its simplicity and effectiveness, and many variants have been proposed. In this paper, a novel Particle Swarm Optimization algorithm is presented, in which the information of the best neighbor of each particle and the best particle of the entire population in the current iteration is considered. Meanwhile, to avoid premature, an abandoned mechanism is used. Furthermore, for improving the global convergence speed of our algorithm, a chaotic search is adopted in the best solution of the current iteration. To verify the performance of our algorithm, standard test functions have been employed. The experimental results show that the algorithm is much more robust and efficient than some existing Particle Swarm Optimization algorithms.

  12. Optimization strategies in complex systems

    Bussolari, L.; Contucci, P.; Giardinà, C.; Giberti, C.; Unguendoli, F.; Vernia, C.

    2003-01-01

    We consider a class of combinatorial optimization problems that emerge in a variety of domains among which: condensed matter physics, theory of financial risks, error correcting codes in information transmissions, molecular and protein conformation, image restoration. We show the performances of two

  13. Simulation analysis of globally integrated logistics and recycling strategies

    Song, S.J.; Hiroshi, K. [Hiroshima Inst. of Tech., Graduate School of Mechanical Systems Engineering, Dept. of In formation and Intelligent Systems Engineering, Hiroshima (Japan)

    2004-07-01

    This paper focuses on the optimal analysis of world-wide recycling activities associated with managing the logistics and production activities in global manufacturing whose activities stretch across national boundaries. Globally integrated logistics and recycling strategies consist of the home country and two free trading economic blocs, NAFTA and ASEAN, where significant differences are found in production and disassembly cost, tax rates, local content rules and regulations. Moreover an optimal analysis of globally integrated value-chain was developed by applying simulation optimization technique as a decision-making tool. The simulation model was developed and analyzed by using ProModel packages, and the results help to identify some of the appropriate conditions required to make well-performed logistics and recycling plans in world-wide collaborated manufacturing environment. (orig.)

  14. Optimal Advance Selling Strategy under Price Commitment

    Chenhang Zeng

    2012-01-01

    This paper considers a two-period model with experienced consumers and inexperienced consumers. The retailer determines both advance selling price and regular selling price at the beginning of the first period. I show that advance selling weekly dominates no advance selling, and the optimal advance selling price may be at a discount, at a premium or at the regular selling price. To help the retailer choose the optimal pricing strategy, conditions for each possible advance selling strategy to ...

  15. Competing intelligent search agents in global optimization

    Streltsov, S.; Vakili, P. [Boston Univ., MA (United States); Muchnik, I. [Rutgers Univ., Piscataway, NJ (United States)

    1996-12-31

    In this paper we present a new search methodology that we view as a development of intelligent agent approach to the analysis of complex system. The main idea is to consider search process as a competition mechanism between concurrent adaptive intelligent agents. Agents cooperate in achieving a common search goal and at the same time compete with each other for computational resources. We propose a statistical selection approach to resource allocation between agents that leads to simple and efficient on average index allocation policies. We use global optimization as the most general setting that encompasses many types of search problems, and show how proposed selection policies can be used to improve and combine various global optimization methods.

  16. Global Optimization Ensemble Model for Classification Methods

    Anwar, Hina; Qamar, Usman; Muzaffar Qureshi, Abdul Wahab

    2014-01-01

    Supervised learning is the process of data mining for deducing rules from training datasets. A broad array of supervised learning algorithms exists, every one of them with its own advantages and drawbacks. There are some basic issues that affect the accuracy of classifier while solving a supervised learning problem, like bias-variance tradeoff, dimensionality of input space, and noise in the input data space. All these problems affect the accuracy of classifier and are the reason that there is no global optimal method for classification. There is not any generalized improvement method that can increase the accuracy of any classifier while addressing all the problems stated above. This paper proposes a global optimization ensemble model for classification methods (GMC) that can improve the overall accuracy for supervised learning problems. The experimental results on various public datasets showed that the proposed model improved the accuracy of the classification models from 1% to 30% depending upon the algorithm complexity. PMID:24883382

  17. Global Optimization Ensemble Model for Classification Methods

    Hina Anwar

    2014-01-01

    Full Text Available Supervised learning is the process of data mining for deducing rules from training datasets. A broad array of supervised learning algorithms exists, every one of them with its own advantages and drawbacks. There are some basic issues that affect the accuracy of classifier while solving a supervised learning problem, like bias-variance tradeoff, dimensionality of input space, and noise in the input data space. All these problems affect the accuracy of classifier and are the reason that there is no global optimal method for classification. There is not any generalized improvement method that can increase the accuracy of any classifier while addressing all the problems stated above. This paper proposes a global optimization ensemble model for classification methods (GMC that can improve the overall accuracy for supervised learning problems. The experimental results on various public datasets showed that the proposed model improved the accuracy of the classification models from 1% to 30% depending upon the algorithm complexity.

  18. Optimization strategies for discrete multi-material stiffness optimization

    Hvejsel, Christian Frier; Lund, Erik; Stolpe, Mathias

    2011-01-01

    Design of composite laminated lay-ups are formulated as discrete multi-material selection problems. The design problem can be modeled as a non-convex mixed-integer optimization problem. Such problems are in general only solvable to global optimality for small to moderate sized problems. To attack...... which numerically confirm the sought properties of the new scheme in terms of convergence to a discrete solution....

  19. Solving global optimization problems on GPU cluster

    Barkalov, Konstantin; Gergel, Victor; Lebedev, Ilya [Lobachevsky State University of Nizhni Novgorod, Gagarin Avenue 23, 603950 Nizhni Novgorod (Russian Federation)

    2016-06-08

    The paper contains the results of investigation of a parallel global optimization algorithm combined with a dimension reduction scheme. This allows solving multidimensional problems by means of reducing to data-independent subproblems with smaller dimension solved in parallel. The new element implemented in the research consists in using several graphic accelerators at different computing nodes. The paper also includes results of solving problems of well-known multiextremal test class GKLS on Lobachevsky supercomputer using tens of thousands of GPU cores.

  20. Research Methodology in Global Strategy Research

    Cuervo-Cazurra, Alvaro; Mudambi, Ram; Pedersen, Torben

    2017-01-01

    We review advances in research methodology used in global strategy research and provide suggestions on how researchers can improve their analyses and arguments. Methodological advances in the extraction of information, such as computer-aided text analysis, and in the analysis of datasets......, such as differences-in-differences and propensity score matching, have helped deal with challenges (e.g., endogeneity and causality) that bedeviled earlier studies and resulted in conflicting findings. These methodological advances need to be considered as tools that complement theoretical arguments and well......-explained logics and mechanisms so that researchers can provide better and more relevant recommendations to managers designing the global strategies of their organizations....

  1. Tank Waste Remediation System optimized processing strategy

    Slaathaug, E.J.; Boldt, A.L.; Boomer, K.D.; Galbraith, J.D.; Leach, C.E.; Waldo, T.L.

    1996-03-01

    This report provides an alternative strategy evolved from the current Hanford Site Tank Waste Remediation System (TWRS) programmatic baseline for accomplishing the treatment and disposal of the Hanford Site tank wastes. This optimized processing strategy performs the major elements of the TWRS Program, but modifies the deployment of selected treatment technologies to reduce the program cost. The present program for development of waste retrieval, pretreatment, and vitrification technologies continues, but the optimized processing strategy reuses a single facility to accomplish the separations/low-activity waste (LAW) vitrification and the high-level waste (HLW) vitrification processes sequentially, thereby eliminating the need for a separate HLW vitrification facility

  2. Optimal control of anthracnose using mixed strategies.

    Fotsa Mbogne, David Jaures; Thron, Christopher

    2015-11-01

    In this paper we propose and study a spatial diffusion model for the control of anthracnose disease in a bounded domain. The model is a generalization of the one previously developed in [15]. We use the model to simulate two different types of control strategies against anthracnose disease. Strategies that employ chemical fungicides are modeled using a continuous control function; while strategies that rely on cultivational practices (such as pruning and removal of mummified fruits) are modeled with a control function which is discrete in time (though not in space). For comparative purposes, we perform our analyses for a spatially-averaged model as well as the space-dependent diffusion model. Under weak smoothness conditions on parameters we demonstrate the well-posedness of both models by verifying existence and uniqueness of the solution for the growth inhibition rate for given initial conditions. We also show that the set [0, 1] is positively invariant. We first study control by impulsive strategies, then analyze the simultaneous use of mixed continuous and pulse strategies. In each case we specify a cost functional to be minimized, and we demonstrate the existence of optimal control strategies. In the case of pulse-only strategies, we provide explicit algorithms for finding the optimal control strategies for both the spatially-averaged model and the space-dependent model. We verify the algorithms for both models via simulation, and discuss properties of the optimal solutions. Copyright © 2015 Elsevier Inc. All rights reserved.

  3. A perturbed martingale approach to global optimization

    Sarkar, Saikat [Computational Mechanics Lab, Department of Civil Engineering, Indian Institute of Science, Bangalore 560012 (India); Roy, Debasish, E-mail: royd@civil.iisc.ernet.in [Computational Mechanics Lab, Department of Civil Engineering, Indian Institute of Science, Bangalore 560012 (India); Vasu, Ram Mohan [Department of Instrumentation and Applied Physics, Indian Institute of Science, Bangalore 560012 (India)

    2014-08-01

    A new global stochastic search, guided mainly through derivative-free directional information computable from the sample statistical moments of the design variables within a Monte Carlo setup, is proposed. The search is aided by imparting to the directional update term additional layers of random perturbations referred to as ‘coalescence’ and ‘scrambling’. A selection step, constituting yet another avenue for random perturbation, completes the global search. The direction-driven nature of the search is manifest in the local extremization and coalescence components, which are posed as martingale problems that yield gain-like update terms upon discretization. As anticipated and numerically demonstrated, to a limited extent, against the problem of parameter recovery given the chaotic response histories of a couple of nonlinear oscillators, the proposed method appears to offer a more rational, more accurate and faster alternative to most available evolutionary schemes, prominently the particle swarm optimization. - Highlights: • Evolutionary global optimization is posed as a perturbed martingale problem. • Resulting search via additive updates is a generalization over Gateaux derivatives. • Additional layers of random perturbation help avoid trapping at local extrema. • The approach ensures efficient design space exploration and high accuracy. • The method is numerically assessed via parameter recovery of chaotic oscillators.

  4. [Global and national strategies against antibiotic resistance].

    Abu Sin, Muna; Nahrgang, Saskia; Ziegelmann, Antina; Clarici, Alexandra; Matz, Sibylle; Tenhagen, Bernd-Alois; Eckmanns, Tim

    2018-05-01

    Antimicrobial resistance (AMR) is increasingly perceived as a global health problem. To tackle AMR effectively, a multisectoral one health approach is needed. We present some of the initiatives and activities at the national and global level that target the AMR challenge. The Global Action Plan on AMR, which has been developed by the World Health Organization (WHO), in close collaboration with the Food and Agriculture Organization of the United Nations (FAO) and the World Organisation for Animal Health (OIE) is considered a blueprint to combat AMR. Member states endorsed the action plan during the World Health Assembly 2015 and committed themselves to develop national action plans on AMR. The German Antibiotic Resistance Strategy (DART 2020) is based on the main objectives of the global action plan and was revised and published in 2015. Several examples of the implementation of DART 2020 are outlined here.

  5. Optimal Pricing Strategy in Marketing Research Consulting.

    Chang, Chun-Hao; Lee, Chi-Wen Jevons

    1994-01-01

    This paper studies the optimal pricing scheme for a monopolistic marketing research consultant who sells high-cost proprietary marketing information to her oligopolistic clients in the manufacturing industry. In designing an optimal pricing strategy, the consultant needs to fully consider the behavior of her clients, the behavior of the existing and potential competitors to her clients, and the behavior of her clients' customers. The authors show how the environment uncertainty, the capabilit...

  6. Optimal Deterministic Investment Strategies for Insurers

    Ulrich Rieder

    2013-11-01

    Full Text Available We consider an insurance company whose risk reserve is given by a Brownian motion with drift and which is able to invest the money into a Black–Scholes financial market. As optimization criteria, we treat mean-variance problems, problems with other risk measures, exponential utility and the probability of ruin. Following recent research, we assume that investment strategies have to be deterministic. This leads to deterministic control problems, which are quite easy to solve. Moreover, it turns out that there are some interesting links between the optimal investment strategies of these problems. Finally, we also show that this approach works in the Lévy process framework.

  7. Optimization of fuel cycle strategies with constraints on uranium availability

    Silvennoinen, P.; Vira, J.; Westerberg, R.

    1982-01-01

    Optimization of nuclear reactor and fuel cycle strategies is studied under the influence of reduced availability of uranium. The analysis is separated in two distinct steps. First, the global situation is considered within given high and low projections of the installed capacity up to the year 2025. Uranium is regarded as an exhaustible resource whose production cost would increase proportionally to increasing cumulative exploitation. Based on the estimates obtained for the uranium cost, a global strategy is derived by splitting the installed capacity between light water reactor (LWR) once-through, LWR recycle, and fast breeder reactor (FBR) alternatives. In the second phase, the nuclear program of an individual utility is optimized within the constraints imposed from the global scenario. Results from the global scenarios indicate that in a reference case the uranium price would triple by the year 2000, and the price escalation would continue throughout the planning period. In a pessimistic growth scenario where the global nuclear capacity would not exceed 600 GW(electric) in 2025, the uranium price would almost double by 2000. In both global scenarios, FBRs would be introduced, in the reference case after 2000 and in the pessimistic case after 2010. In spite of the increases in the uranium prices, the levelized power production cost would increase only by 45% up to 2025 in the utility case provided that the plutonium is incinerated as a substitute fuel

  8. Dual Schroedinger Equation as Global Optimization Algorithm

    Huang Xiaofei; eGain Communications, Mountain View, CA 94043

    2011-01-01

    The dual Schroedinger equation is defined as replacing the imaginary number i by -1 in the original one. This paper shows that the dual equation shares the same stationary states as the original one. Different from the original one, it explicitly defines a dynamic process for a system to evolve from any state to lower energy states and eventually to the lowest one. Its power as a global optimization algorithm might be used by nature for constructing atoms and molecules. It shall be interesting to verify its existence in nature.

  9. National action strategy on global warming

    1990-11-01

    A document prepared by a committee of Canadian environmental ministries proposes a strategic framework for a national action plan concerning global warming. The strategy would be carried out jointly by governments and all other sectors of the economy, taking into account the present state of scientific knowledge on global warming. Within this framework, the governments in cooperation with interested parties would take certain measures in their respective areas of competence. The main recommendations of the document include the following. The action strategy should comprise 3 elements: limiting emissions of greenhouse gases; forecasting climatic changes which Canada could undergo due to global warming and preparing for such changes; and improving scientific knowledge and the capacity to predict climatic changes. Limitations on this strategy should take into account such matters as the interaction of greenhouse gases with other pollutants, the importance of the international context, the need to adapt to new discoveries, and the importance of regional differences. Implementation of the strategy should incorporate widespread consultation of all affected sectors, sustained work on establishing international conventions and protocols on reducing greenhouse gas emissions, objectives and schedules for such reductions, and stepwise actions to control emissions in order to enable an adequate evaluation of the consequences and effectiveness of such measures. 10 figs., 2 tabs

  10. Optimization strategies for complex engineering applications

    Eldred, M.S.

    1998-02-01

    LDRD research activities have focused on increasing the robustness and efficiency of optimization studies for computationally complex engineering problems. Engineering applications can be characterized by extreme computational expense, lack of gradient information, discrete parameters, non-converging simulations, and nonsmooth, multimodal, and discontinuous response variations. Guided by these challenges, the LDRD research activities have developed application-specific techniques, fundamental optimization algorithms, multilevel hybrid and sequential approximate optimization strategies, parallel processing approaches, and automatic differentiation and adjoint augmentation methods. This report surveys these activities and summarizes the key findings and recommendations.

  11. Optimal design of RTCs in digital circuit fault self-repair based on global signal optimization

    Zhang Junbin; Cai Jinyan; Meng Yafeng

    2016-01-01

    Since digital circuits have been widely and thoroughly applied in various fields, electronic systems are increasingly more complicated and require greater reliability. Faults may occur in elec-tronic systems in complicated environments. If immediate field repairs are not made on the faults, elec-tronic systems will not run normally, and this will lead to serious losses. The traditional method for improving system reliability based on redundant fault-tolerant technique has been unable to meet the requirements. Therefore, on the basis of (evolvable hardware)-based and (reparation balance technology)-based electronic circuit fault self-repair strategy proposed in our preliminary work, the optimal design of rectification circuits (RTCs) in electronic circuit fault self-repair based on global sig-nal optimization is deeply researched in this paper. First of all, the basic theory of RTC optimal design based on global signal optimization is proposed. Secondly, relevant considerations and suitable ranges are analyzed. Then, the basic flow of RTC optimal design is researched. Eventually, a typical circuit is selected for simulation verification, and detailed simulated analysis is made on five circumstances that occur during RTC evolution. The simulation results prove that compared with the conventional design method based RTC, the global signal optimization design method based RTC is lower in hardware cost, faster in circuit evolution, higher in convergent precision, and higher in circuit evolution success rate. Therefore, the global signal optimization based RTC optimal design method applied in the elec-tronic circuit fault self-repair technology is proven to be feasible, effective, and advantageous.

  12. Globally optimal superconducting magnets part II: symmetric MSE coil arrangement.

    Tieng, Quang M; Vegh, Viktor; Brereton, Ian M

    2009-01-01

    A globally optimal superconducting magnet coil design procedure based on the Minimum Stored Energy (MSE) current density map is outlined. The method has the ability to arrange coils in a manner that generates a strong and homogeneous axial magnetic field over a predefined region, and ensures the stray field external to the assembly and peak magnetic field at the wires are in acceptable ranges. The outlined strategy of allocating coils within a given domain suggests that coils should be placed around the perimeter of the domain with adjacent coils possessing alternating winding directions for optimum performance. The underlying current density maps from which the coils themselves are derived are unique, and optimized to possess minimal stored energy. Therefore, the method produces magnet designs with the lowest possible overall stored energy. Optimal coil layouts are provided for unshielded and shielded short bore symmetric superconducting magnets.

  13. Global Optimization using Interval Analysis : Interval Optimization for Aerospace Applications

    Van Kampen, E.

    2010-01-01

    Optimization is an important element in aerospace related research. It is encountered for example in trajectory optimization problems, such as: satellite formation flying, spacecraft re-entry optimization and airport approach and departure optimization; in control optimization, for example in

  14. Nuclear power development: global challenges and strategies

    Mourogov, Victor M.; )

    1997-01-01

    This article highlights key factors that will determine today and tomorrow's optimal energy strategies. It addresses methods to utilize the high potential energy content of uranium. Plutonium used as fuel in a nuclear reactors is discussed as is the future potential of a thorium fuel cycle. Various strategies to increase the economic viability of nuclear power are brought out. Technological means to further minimize environmental impacts and to enhance safety are covered as they are a major factor in public acceptance. Also covered are advances anticipated by mid-century in nuclear reactor and fuel cycle technologies

  15. Ford Motor Company's Global Electrification Strategy

    Ellen Hughes-Cromwick

    2011-01-01

    Ford Motor Company has developed global platforms for its vehicles, including hybrid electric vehicles and forthcoming battery-electric and plug-in hybrids. Providing electrification technologies is a key element of Ford's broader strategy of producing vehicles that have improved fuel economy and reduced greenhouse emissions. The breadth of this effort—across a range of vehicle types—is unique in the automotive industry. Of particular importance is using the same vehicle platforms for electri...

  16. Global Cities and Multinational Enterprise Location Strategy

    Goerzen, Anthony; Geisler Asmussen, Christian; Nielsen, Bo Bernhard

    2013-01-01

    We combine the concept of location derived by economic geographers with theories of the multinational enterprise (MNE) and the liability of foreignness developed by international business scholars, to examine the factors that propel MNEs toward, or away from, “global cities”. We argue that three...... distinctive characteristics of global cities – global interconnectedness, cosmopolitanism, and abundance of advanced producer services – help MNEs overcome the costs of doing business abroad, and we identify the contingencies under which these characteristics combine with firm attributes to exert......- and subsidiary-level factors, including investment motives, proprietary capabilities, and business strategy. Our study provides important insights for international business scholars by shedding new light on MNE location choices and also contributes to our understanding of economic geography by examining...

  17. Global warming: Towards a strategy for Ontario

    1990-01-01

    A discussion paper is provided as background to a proposed public review of a strategy for Ontario's response to global warming. Global warming arises from the generation of greenhouse gases, which come from the use of fossil fuels, the use of chlorofluorocarbons, and deforestation. Energy policy is the backbone of achieving climate stability since the burning of fossil fuels releases most of the greenhouse gases, mainly carbon dioxide. Canada is, by international standards, a very energy-intensive country and is among the world's largest emitters of carbon dioxide on a per capita basis. Ontario is the largest energy-using province in Canada, and fossil fuels represent over 80% of provincial energy use. A proposed goal for Ontario is to provide leadership in stabilizing atmospheric concentrations of the greenhouse gases, while minimizing the social, economic, and environmental costs in Ontario of adapting to global warming. A proposed first step to address global warming is to achieve reductions in expected emissions of the greenhouse gases, especially carbon dioxide, so that levels by the year 2000 are lower than in 1989. Current policies and regulations helping to reduce the greenhouse effect include some of the current controls on automotive emissions and the adoption by the provincial electric utility of targets to reduce electricity demand. New initiatives include establishment of minimum energy efficiency standards and reduction of peak-day electricity use. Action steps for future consideration are detailed in the categories of greenhouse gas emissions reductions, carbon dioxide absorption, and research and analysis into global warming

  18. Parallel strategy for optimal learning in perceptrons

    Neirotti, J P

    2010-01-01

    We developed a parallel strategy for learning optimally specific realizable rules by perceptrons, in an online learning scenario. Our result is a generalization of the Caticha-Kinouchi (CK) algorithm developed for learning a perceptron with a synaptic vector drawn from a uniform distribution over the N-dimensional sphere, so called the typical case. Our method outperforms the CK algorithm in almost all possible situations, failing only in a denumerable set of cases. The algorithm is optimal in the sense that it saturates Bayesian bounds when it succeeds.

  19. The Optimal Nash Equilibrium Strategies Under Competition

    孟力; 王崇喜; 汪定伟; 张爱玲

    2004-01-01

    This paper presented a game theoretic model to study the competition for a single investment oppertunity under uncertainty. It models the hazard rate of investment as a function of competitors' trigger level. Under uncertainty and different information structure, the option and game theory was applied to researching the optimal Nash equilibrium strategies of one or more firm. By means of Matlab software, the paper simulates a real estate developing project example and illustrates how parameter affects investment strategies. The paper's work will contribute to the present investment practice in China.

  20. Particle Swarm Optimization With Interswarm Interactive Learning Strategy.

    Qin, Quande; Cheng, Shi; Zhang, Qingyu; Li, Li; Shi, Yuhui

    2016-10-01

    The learning strategy in the canonical particle swarm optimization (PSO) algorithm is often blamed for being the primary reason for loss of diversity. Population diversity maintenance is crucial for preventing particles from being stuck into local optima. In this paper, we present an improved PSO algorithm with an interswarm interactive learning strategy (IILPSO) by overcoming the drawbacks of the canonical PSO algorithm's learning strategy. IILPSO is inspired by the phenomenon in human society that the interactive learning behavior takes place among different groups. Particles in IILPSO are divided into two swarms. The interswarm interactive learning (IIL) behavior is triggered when the best particle's fitness value of both the swarms does not improve for a certain number of iterations. According to the best particle's fitness value of each swarm, the softmax method and roulette method are used to determine the roles of the two swarms as the learning swarm and the learned swarm. In addition, the velocity mutation operator and global best vibration strategy are used to improve the algorithm's global search capability. The IIL strategy is applied to PSO with global star and local ring structures, which are termed as IILPSO-G and IILPSO-L algorithm, respectively. Numerical experiments are conducted to compare the proposed algorithms with eight popular PSO variants. From the experimental results, IILPSO demonstrates the good performance in terms of solution accuracy, convergence speed, and reliability. Finally, the variations of the population diversity in the entire search process provide an explanation why IILPSO performs effectively.

  1. A practical globalization of one-shot optimization for optimal design of tokamak divertors

    Blommaert, Maarten, E-mail: maarten.blommaert@kuleuven.be [Institute of Energy and Climate Research (IEK-4), FZ Jülich GmbH, D-52425 Jülich (Germany); Dekeyser, Wouter; Baelmans, Martine [KU Leuven, Department of Mechanical Engineering, 3001 Leuven (Belgium); Gauger, Nicolas R. [TU Kaiserslautern, Chair for Scientific Computing, 67663 Kaiserslautern (Germany); Reiter, Detlev [Institute of Energy and Climate Research (IEK-4), FZ Jülich GmbH, D-52425 Jülich (Germany)

    2017-01-01

    In past studies, nested optimization methods were successfully applied to design of the magnetic divertor configuration in nuclear fusion reactors. In this paper, so-called one-shot optimization methods are pursued. Due to convergence issues, a globalization strategy for the one-shot solver is sought. Whereas Griewank introduced a globalization strategy using a doubly augmented Lagrangian function that includes primal and adjoint residuals, its practical usability is limited by the necessity of second order derivatives and expensive line search iterations. In this paper, a practical alternative is offered that avoids these drawbacks by using a regular augmented Lagrangian merit function that penalizes only state residuals. Additionally, robust rank-two Hessian estimation is achieved by adaptation of Powell's damped BFGS update rule. The application of the novel one-shot approach to magnetic divertor design is considered in detail. For this purpose, the approach is adapted to be complementary with practical in parts adjoint sensitivities. Using the globalization strategy, stable convergence of the one-shot approach is achieved.

  2. Optimized Strategies for Detecting Extrasolar Space Weather

    Hallinan, Gregg

    2018-06-01

    Fully understanding the implications of space weather for the young solar system, as well as the wider population of planet-hosting stars, requires remote sensing of space weather in other stellar systems. Solar coronal mass ejections can be accompanied by bright radio bursts at low frequencies (typically measurement of the magnetic field strength of the planet, informing on whether the atmosphere of the planet can survive the intense magnetic activity of its host star. However, both stellar and planetary radio emission are highly variable and optimal strategies for detection of these emissions requires the capability to monitor 1000s of nearby stellar/planetary systems simultaneously. I will discuss optimized strategies for both ground and space-based experiments to take advantage of the highly variable nature of the radio emissions powered by extrasolar space weather to enable detection of stellar CMEs and planetary magnetospheres.

  3. A hybrid bird mating optimizer algorithm with teaching-learning-based optimization for global numerical optimization

    Qingyang Zhang

    2015-02-01

    Full Text Available Bird Mating Optimizer (BMO is a novel meta-heuristic optimization algorithm inspired by intelligent mating behavior of birds. However, it is still insufficient in convergence of speed and quality of solution. To overcome these drawbacks, this paper proposes a hybrid algorithm (TLBMO, which is established by combining the advantages of Teaching-learning-based optimization (TLBO and Bird Mating Optimizer (BMO. The performance of TLBMO is evaluated on 23 benchmark functions, and compared with seven state-of-the-art approaches, namely BMO, TLBO, Artificial Bee Bolony (ABC, Particle Swarm Optimization (PSO, Fast Evolution Programming (FEP, Differential Evolution (DE, Group Search Optimization (GSO. Experimental results indicate that the proposed method performs better than other existing algorithms for global numerical optimization.

  4. Optimization of pocket machining strategy in HSM

    Msaddek, El Bechir; Bouaziz, Zoubeir; Dessein, Gilles; Baili, Maher

    2012-01-01

    International audience; Our two major concerns, which should be taken into consideration as soon as we start the selecting the machining parameters, are the minimization of the machining time and the maintaining of the high-speed machining machine in good state. The manufacturing strategy is one of the parameters which practically influences the time of the different geometrical forms manufacturing, as well as the machine itself. In this article, we propose an optimization methodology of the ...

  5. Optimal strategies for pricing general insurance

    Emms, P.; Haberman, S.; Savoulli, I.

    2006-01-01

    Optimal premium pricing policies in a competitive insurance environment are investigated using approximation methods and simulation of sample paths. The market average premium is modelled as a diffusion process, with the premium as the control function and the maximization of the expected total utility of wealth, over a finite time horizon, as the objective. In order to simplify the optimisation problem, a linear utility function is considered and two particular premium strategies are adopted...

  6. Base-of-the-pyramid global strategy

    Boşcor, D.

    2010-12-01

    Full Text Available Global strategies for MNCs should focus on customers in emerging and developing markets instead of customers in developed economies. The “base-of-the-pyramid segment” comprises 4 billion people in the world. In order to be successful, companies will be required to form unconventional partnerships- with entities ranging from local governments to non-profit organizations - to gain the community’s trust and understand the environmental, infrastructure and political issues that may affect business. Being able to provide affordable, high-quality products and services in this market segment often means new approaches to marketing- new packaging and pricing structures, and using unfamiliar distribution structures.

  7. An Adaptive Unified Differential Evolution Algorithm for Global Optimization

    Qiang, Ji; Mitchell, Chad

    2014-11-03

    In this paper, we propose a new adaptive unified differential evolution algorithm for single-objective global optimization. Instead of the multiple mutation strate- gies proposed in conventional differential evolution algorithms, this algorithm employs a single equation unifying multiple strategies into one expression. It has the virtue of mathematical simplicity and also provides users the flexibility for broader exploration of the space of mutation operators. By making all control parameters in the proposed algorithm self-adaptively evolve during the process of optimization, it frees the application users from the burden of choosing appro- priate control parameters and also improves the performance of the algorithm. In numerical tests using thirteen basic unimodal and multimodal functions, the proposed adaptive unified algorithm shows promising performance in compari- son to several conventional differential evolution algorithms.

  8. Global optimization applied to GPS positioning by ambiguity functions

    Baselga, Sergio

    2010-01-01

    Differential GPS positioning with carrier-phase observables is commonly done in a process that involves determination of the unknown integer ambiguity values. An alternative approach, named the ambiguity function method, was already proposed in the early days of GPS positioning. By making use of a trigonometric function ambiguity unknowns are eliminated from the functional model before the estimation process. This approach has significant advantages, such as ease of use and insensitivity to cycle slips, but requires such high accuracy in the initial approximate coordinates that its use has been practically dismissed from consideration. In this paper a novel strategy is proposed so that the need for highly accurate initial coordinates disappears: the application of a global optimization method to the ambiguity functions model. The use of this strategy enables the ambiguity function method to compete with the present prevailing approach of ambiguity resolution

  9. Parallel Global Optimization with the Particle Swarm Algorithm (Preprint)

    Schutte, J. F; Reinbolt, J. A; Fregly, B. J; Haftka, R. T; George, A. D

    2004-01-01

    .... To obtain enhanced computational throughput and global search capability, we detail the coarse-grained parallelization of an increasingly popular global search method, the Particle Swarm Optimization (PSO) algorithm...

  10. A Global Network Alignment Method Using Discrete Particle Swarm Optimization.

    Huang, Jiaxiang; Gong, Maoguo; Ma, Lijia

    2016-10-19

    Molecular interactions data increase exponentially with the advance of biotechnology. This makes it possible and necessary to comparatively analyse the different data at a network level. Global network alignment is an important network comparison approach to identify conserved subnetworks and get insight into evolutionary relationship across species. Network alignment which is analogous to subgraph isomorphism is known to be an NP-hard problem. In this paper, we introduce a novel heuristic Particle-Swarm-Optimization based Network Aligner (PSONA), which optimizes a weighted global alignment model considering both protein sequence similarity and interaction conservations. The particle statuses and status updating rules are redefined in a discrete form by using permutation. A seed-and-extend strategy is employed to guide the searching for the superior alignment. The proposed initialization method "seeds" matches with high sequence similarity into the alignment, which guarantees the functional coherence of the mapping nodes. A greedy local search method is designed as the "extension" procedure to iteratively optimize the edge conservations. PSONA is compared with several state-of-art methods on ten network pairs combined by five species. The experimental results demonstrate that the proposed aligner can map the proteins with high functional coherence and can be used as a booster to effectively refine the well-studied aligners.

  11. Priority Selection Within National Innovation Strategy in Global Context

    Prokopenko Olha

    2017-08-01

    Full Text Available The article deals with global experience in analysing the priorities based on their importance for country development and on national and international criteria using algorithm for the selection process. The main aspects of the process of development and implementation of international technology strategies were considered. The authors prove that through the analysis of innovation systems at macro level decision about the priorities in optimization with the aim to improve regulations in science, technology and innovation is provided. The main techniques and decisions were considered based on foresight-studies. Authors propose to create informative and analytical system for the foresight aims.

  12. Optimization Under Uncertainty for Wake Steering Strategies

    Quick, Julian [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Annoni, Jennifer [National Renewable Energy Laboratory (NREL), Golden, CO (United States); King, Ryan N [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Dykes, Katherine L [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Fleming, Paul A [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Ning, Andrew [Brigham Young University

    2017-08-03

    Offsetting turbines' yaw orientations from incoming wind is a powerful tool that may be leveraged to reduce undesirable wake effects on downstream turbines. First, we examine a simple two-turbine case to gain intuition as to how inflow direction uncertainty affects the optimal solution. The turbines are modeled with unidirectional inflow such that one turbine directly wakes the other, using ten rotor diameter spacing. We perform optimization under uncertainty (OUU) via a parameter sweep of the front turbine. The OUU solution generally prefers less steering. We then do this optimization for a 60-turbine wind farm with unidirectional inflow, varying the degree of inflow uncertainty and approaching this OUU problem by nesting a polynomial chaos expansion uncertainty quantification routine within an outer optimization. We examined how different levels of uncertainty in the inflow direction effect the ratio of the expected values of deterministic and OUU solutions for steering strategies in the large wind farm, assuming the directional uncertainty used to reach said OUU solution (this ratio is defined as the value of the stochastic solution or VSS).

  13. Simulated Annealing-Based Krill Herd Algorithm for Global Optimization

    Gai-Ge Wang

    2013-01-01

    Full Text Available Recently, Gandomi and Alavi proposed a novel swarm intelligent method, called krill herd (KH, for global optimization. To enhance the performance of the KH method, in this paper, a new improved meta-heuristic simulated annealing-based krill herd (SKH method is proposed for optimization tasks. A new krill selecting (KS operator is used to refine krill behavior when updating krill’s position so as to enhance its reliability and robustness dealing with optimization problems. The introduced KS operator involves greedy strategy and accepting few not-so-good solutions with a low probability originally used in simulated annealing (SA. In addition, a kind of elitism scheme is used to save the best individuals in the population in the process of the krill updating. The merits of these improvements are verified by fourteen standard benchmarking functions and experimental results show that, in most cases, the performance of this improved meta-heuristic SKH method is superior to, or at least highly competitive with, the standard KH and other optimization methods.

  14. On the Performance of Linear Decreasing Inertia Weight Particle Swarm Optimization for Global Optimization

    Arasomwan, Martins Akugbe; Adewumi, Aderemi Oluyinka

    2013-01-01

    Linear decreasing inertia weight (LDIW) strategy was introduced to improve on the performance of the original particle swarm optimization (PSO). However, linear decreasing inertia weight PSO (LDIW-PSO) algorithm is known to have the shortcoming of premature convergence in solving complex (multipeak) optimization problems due to lack of enough momentum for particles to do exploitation as the algorithm approaches its terminal point. Researchers have tried to address this shortcoming by modifying LDIW-PSO or proposing new PSO variants. Some of these variants have been claimed to outperform LDIW-PSO. The major goal of this paper is to experimentally establish the fact that LDIW-PSO is very much efficient if its parameters are properly set. First, an experiment was conducted to acquire a percentage value of the search space limits to compute the particle velocity limits in LDIW-PSO based on commonly used benchmark global optimization problems. Second, using the experimentally obtained values, five well-known benchmark optimization problems were used to show the outstanding performance of LDIW-PSO over some of its competitors which have in the past claimed superiority over it. Two other recent PSO variants with different inertia weight strategies were also compared with LDIW-PSO with the latter outperforming both in the simulation experiments conducted. PMID:24324383

  15. Combined optimization model for sustainable energization strategy

    Abtew, Mohammed Seid

    Access to energy is a foundation to establish a positive impact on multiple aspects of human development. Both developed and developing countries have a common concern of achieving a sustainable energy supply to fuel economic growth and improve the quality of life with minimal environmental impacts. The Least Developing Countries (LDCs), however, have different economic, social, and energy systems. Prevalence of power outage, lack of access to electricity, structural dissimilarity between rural and urban regions, and traditional fuel dominance for cooking and the resultant health and environmental hazards are some of the distinguishing characteristics of these nations. Most energy planning models have been designed for developed countries' socio-economic demographics and have missed the opportunity to address special features of the poor countries. An improved mixed-integer programming energy-source optimization model is developed to address limitations associated with using current energy optimization models for LDCs, tackle development of the sustainable energization strategies, and ensure diversification and risk management provisions in the selected energy mix. The Model predicted a shift from traditional fuels reliant and weather vulnerable energy source mix to a least cost and reliable modern clean energy sources portfolio, a climb on the energy ladder, and scored multifaceted economic, social, and environmental benefits. At the same time, it represented a transition strategy that evolves to increasingly cleaner energy technologies with growth as opposed to an expensive solution that leapfrogs immediately to the cleanest possible, overreaching technologies.

  16. Local Optimization Strategies in Urban Vehicular Mobility.

    Pierpaolo Mastroianni

    Full Text Available The comprehension of vehicular traffic in urban environments is crucial to achieve a good management of the complex processes arising from people collective motion. Even allowing for the great complexity of human beings, human behavior turns out to be subject to strong constraints--physical, environmental, social, economic--that induce the emergence of common patterns. The observation and understanding of those patterns is key to setup effective strategies to optimize the quality of life in cities while not frustrating the natural need for mobility. In this paper we focus on vehicular mobility with the aim to reveal the underlying patterns and uncover the human strategies determining them. To this end we analyze a large dataset of GPS vehicles tracks collected in the Rome (Italy district during a month. We demonstrate the existence of a local optimization of travel times that vehicle drivers perform while choosing their journey. This finding is mirrored by two additional important facts, i.e., the observation that the average vehicle velocity increases by increasing the travel length and the emergence of a universal scaling law for the distribution of travel times at fixed traveled length. A simple modeling scheme confirms this scenario opening the way to further predictions.

  17. Optimal sampling strategies for detecting zoonotic disease epidemics.

    Jake M Ferguson

    2014-06-01

    Full Text Available The early detection of disease epidemics reduces the chance of successful introductions into new locales, minimizes the number of infections, and reduces the financial impact. We develop a framework to determine the optimal sampling strategy for disease detection in zoonotic host-vector epidemiological systems when a disease goes from below detectable levels to an epidemic. We find that if the time of disease introduction is known then the optimal sampling strategy can switch abruptly between sampling only from the vector population to sampling only from the host population. We also construct time-independent optimal sampling strategies when conducting periodic sampling that can involve sampling both the host and the vector populations simultaneously. Both time-dependent and -independent solutions can be useful for sampling design, depending on whether the time of introduction of the disease is known or not. We illustrate the approach with West Nile virus, a globally-spreading zoonotic arbovirus. Though our analytical results are based on a linearization of the dynamical systems, the sampling rules appear robust over a wide range of parameter space when compared to nonlinear simulation models. Our results suggest some simple rules that can be used by practitioners when developing surveillance programs. These rules require knowledge of transition rates between epidemiological compartments, which population was initially infected, and of the cost per sample for serological tests.

  18. Optimal sampling strategies for detecting zoonotic disease epidemics.

    Ferguson, Jake M; Langebrake, Jessica B; Cannataro, Vincent L; Garcia, Andres J; Hamman, Elizabeth A; Martcheva, Maia; Osenberg, Craig W

    2014-06-01

    The early detection of disease epidemics reduces the chance of successful introductions into new locales, minimizes the number of infections, and reduces the financial impact. We develop a framework to determine the optimal sampling strategy for disease detection in zoonotic host-vector epidemiological systems when a disease goes from below detectable levels to an epidemic. We find that if the time of disease introduction is known then the optimal sampling strategy can switch abruptly between sampling only from the vector population to sampling only from the host population. We also construct time-independent optimal sampling strategies when conducting periodic sampling that can involve sampling both the host and the vector populations simultaneously. Both time-dependent and -independent solutions can be useful for sampling design, depending on whether the time of introduction of the disease is known or not. We illustrate the approach with West Nile virus, a globally-spreading zoonotic arbovirus. Though our analytical results are based on a linearization of the dynamical systems, the sampling rules appear robust over a wide range of parameter space when compared to nonlinear simulation models. Our results suggest some simple rules that can be used by practitioners when developing surveillance programs. These rules require knowledge of transition rates between epidemiological compartments, which population was initially infected, and of the cost per sample for serological tests.

  19. 3rd World Congress on Global Optimization in Engineering & Science

    Ruan, Ning; Xing, Wenxun; WCGO-III; Advances in Global Optimization

    2015-01-01

    This proceedings volume addresses advances in global optimization—a multidisciplinary research field that deals with the analysis, characterization, and computation of global minima and/or maxima of nonlinear, non-convex, and nonsmooth functions in continuous or discrete forms. The volume contains selected papers from the third biannual World Congress on Global Optimization in Engineering & Science (WCGO), held in the Yellow Mountains, Anhui, China on July 8-12, 2013. The papers fall into eight topical sections: mathematical programming; combinatorial optimization; duality theory; topology optimization; variational inequalities and complementarity problems; numerical optimization; stochastic models and simulation; and complex simulation and supply chain analysis.

  20. 4th International Conference on Frontiers in Global Optimization

    Pardalos, Panos

    2004-01-01

    Global Optimization has emerged as one of the most exciting new areas of mathematical programming. Global optimization has received a wide attraction from many fields in the past few years, due to the success of new algorithms for addressing previously intractable problems from diverse areas such as computational chemistry and biology, biomedicine, structural optimization, computer sciences, operations research, economics, and engineering design and control. This book contains refereed invited papers submitted at the 4th international confer­ ence on Frontiers in Global Optimization held at Santorini, Greece during June 8-12, 2003. Santorini is one of the few sites of Greece, with wild beauty created by the explosion of a volcano which is in the middle of the gulf of the island. The mystic landscape with its numerous mult-extrema, was an inspiring location particularly for researchers working on global optimization. The three previous conferences on "Recent Advances in Global Opti­ mization", "State-of-the-...

  1. Microwave tomography global optimization, parallelization and performance evaluation

    Noghanian, Sima; Desell, Travis; Ashtari, Ali

    2014-01-01

    This book provides a detailed overview on the use of global optimization and parallel computing in microwave tomography techniques. The book focuses on techniques that are based on global optimization and electromagnetic numerical methods. The authors provide parallelization techniques on homogeneous and heterogeneous computing architectures on high performance and general purpose futuristic computers. The book also discusses the multi-level optimization technique, hybrid genetic algorithm and its application in breast cancer imaging.

  2. Optimal allocation of trend following strategies

    Grebenkov, Denis S.; Serror, Jeremy

    2015-09-01

    We consider a portfolio allocation problem for trend following (TF) strategies on multiple correlated assets. Under simplifying assumptions of a Gaussian market and linear TF strategies, we derive analytical formulas for the mean and variance of the portfolio return. We construct then the optimal portfolio that maximizes risk-adjusted return by accounting for inter-asset correlations. The dynamic allocation problem for n assets is shown to be equivalent to the classical static allocation problem for n2 virtual assets that include lead-lag corrections in positions of TF strategies. The respective roles of asset auto-correlations and inter-asset correlations are investigated in depth for the two-asset case and a sector model. In contrast to the principle of diversification suggesting to treat uncorrelated assets, we show that inter-asset correlations allow one to estimate apparent trends more reliably and to adjust the TF positions more efficiently. If properly accounted for, inter-asset correlations are not deteriorative but beneficial for portfolio management that can open new profit opportunities for trend followers. These concepts are illustrated using daily returns of three highly correlated futures markets: the E-mini S&P 500, Euro Stoxx 50 index, and the US 10-year T-note futures.

  3. Decentralized Control Using Global Optimization (DCGO) (Preprint)

    Flint, Matthew; Khovanova, Tanya; Curry, Michael

    2007-01-01

    The coordination of a team of distributed air vehicles requires a complex optimization, balancing limited communication bandwidths, non-instantaneous planning times and network delays, while at the...

  4. Interactive Cosegmentation Using Global and Local Energy Optimization

    Xingping Dong,; Jianbing Shen,; Shao, Ling; Yang, Ming-Hsuan

    2015-01-01

    We propose a novel interactive cosegmentation method using global and local energy optimization. The global energy includes two terms: 1) the global scribbled energy and 2) the interimage energy. The first one utilizes the user scribbles to build the Gaussian mixture model and improve the cosegmentation performance. The second one is a global constraint, which attempts to match the histograms of common objects. To minimize the local energy, we apply the spline regression to learn the smoothne...

  5. Asymptotic estimation of reactor fueling optimal strategy

    Simonov, V.D.

    1985-01-01

    The problem of improving the technical-economic factors of operating. and designed nuclear power plant blocks by developino. internal fuel cycle strategy (reactor fueling regime optimization), taking into account energy system structural peculiarities altogether, is considered. It is shown, that in search of asymptotic solutions of reactor fueling planning tasks the model of fuel energy potential (FEP) is the most ssuitable and effective. FEP represents energy which may be produced from the fuel in a reactor with real dimensions and power, but with hypothetical fresh fuel supply, regime, providing smilar burnup of all the fuel, passing through the reactor, and continuous overloading of infinitely small fuel portion under fule power, and infinitely rapid mixing of fuel in the reactor core volume. Reactor fuel run with such a standard fuel cycle may serve as FEP quantitative measure. Assessment results of optimal WWER-440 reactor fresh fuel supply periodicity are given as an example. The conclusion is drawn that with fuel enrichment x=3.3% the run which is 300 days, is economically justified, taking into account that the cost of one energy unit production is > 3 cop/KW/h

  6. Energy Optimal Control Strategy of PHEV Based on PMP Algorithm

    Tiezhou Wu

    2017-01-01

    Full Text Available Under the global voice of “energy saving” and the current boom in the development of energy storage technology at home and abroad, energy optimal control of the whole hybrid electric vehicle power system, as one of the core technologies of electric vehicles, is bound to become a hot target of “clean energy” vehicle development and research. This paper considers the constraints to the performance of energy storage system in Parallel Hybrid Electric Vehicle (PHEV, from which lithium-ion battery frequently charges/discharges, PHEV largely consumes energy of fuel, and their are difficulty in energy recovery and other issues in a single cycle; the research uses lithium-ion battery combined with super-capacitor (SC, which is hybrid energy storage system (Li-SC HESS, working together with internal combustion engine (ICE to drive PHEV. Combined with PSO-PI controller and Li-SC HESS internal power limited management approach, the research proposes the PHEV energy optimal control strategy. It is based on revised Pontryagin’s minimum principle (PMP algorithm, which establishes the PHEV vehicle simulation model through ADVISOR software and verifies the effectiveness and feasibility. Finally, the results show that the energy optimization control strategy can improve the instantaneity of tracking PHEV minimum fuel consumption track, implement energy saving, and prolong the life of lithium-ion batteries and thereby can improve hybrid energy storage system performance.

  7. GLOBAL TEAM MANAGEMENT: AN ESSENTIAL COMPONENT OF FIRMS’ INNOVATION STRATEGY

    AZİM ÖZTÜRK

    2013-05-01

    Full Text Available In the world marketplace some firms compete successfully and others fail to gain global competitive advantage. Some researchers argue that innovation strategy is the answer to successfully meeting today’s and tomorrow’s global business challenges.  An important aspect of the innovation strategy is managing global teams effectively.  Thus, firms of tomorrow will be characterized by values such as teamwork, innovation, cultural diversity, and a global mindset.  The rapid globalization of business, and increasing competition will continue to drive the need for effective teamwork and/in innovation management.  The purpose of our research is to gain insight into global team management and its role as a major component of innovation strategy.  We discuss the changing and developing functions of teamwork, examine the characteristics of global teams, and finally offer a process to achieve effective global team management.

  8. Theory and Algorithms for Global/Local Design Optimization

    Haftka, Raphael T

    2004-01-01

    ... the component and overall design as well as on exploration of global optimization algorithms. In the former category, heuristic decomposition was followed with proof that it solves the original problem...

  9. Theory and Algorithms for Global/Local Design Optimization

    Watson, Layne T; Guerdal, Zafer; Haftka, Raphael T

    2005-01-01

    The motivating application for this research is the global/local optimal design of composite aircraft structures such as wings and fuselages, but the theory and algorithms are more widely applicable...

  10. Long-term global nuclear energy and fuel cycle strategies

    Krakowski, R.A.

    1997-01-01

    The Global Nuclear Vision Project is examining, using scenario building techniques, a range of long-term nuclear energy futures. The exploration and assessment of optimal nuclear fuel-cycle and material strategies is an essential element of the study. To this end, an established global E 3 (energy/economics/environmental) model has been adopted and modified with a simplified, but comprehensive and multi-regional, nuclear energy module. Consistent nuclear energy scenarios are constructed using this multi-regional E 3 model, wherein future demands for nuclear power are projected in price competition with other energy sources under a wide range of long-term demographic (population, workforce size and productivity), economic (price-, population-, and income-determined demand for energy services, price- and population-modified GNP, resource depletion, world-market fossil energy prices), policy (taxes, tariffs, sanctions), and top-level technological (energy intensity and end-use efficiency improvements) drivers. Using the framework provided by the global E 3 model, the impacts of both external and internal drivers are investigated. The ability to connect external and internal drivers through this modeling framework allows the study of impacts and tradeoffs between fossil- versus nuclear-fuel burning, that includes interactions between cost, environmental, proliferation, resource, and policy issues

  11. Long-term global nuclear energy and fuel cycle strategies

    Krakowski, R.A. [Los Alamos National Lab., NM (United States). Technology and Safety Assessment Div.

    1997-09-24

    The Global Nuclear Vision Project is examining, using scenario building techniques, a range of long-term nuclear energy futures. The exploration and assessment of optimal nuclear fuel-cycle and material strategies is an essential element of the study. To this end, an established global E{sup 3} (energy/economics/environmental) model has been adopted and modified with a simplified, but comprehensive and multi-regional, nuclear energy module. Consistent nuclear energy scenarios are constructed using this multi-regional E{sup 3} model, wherein future demands for nuclear power are projected in price competition with other energy sources under a wide range of long-term demographic (population, workforce size and productivity), economic (price-, population-, and income-determined demand for energy services, price- and population-modified GNP, resource depletion, world-market fossil energy prices), policy (taxes, tariffs, sanctions), and top-level technological (energy intensity and end-use efficiency improvements) drivers. Using the framework provided by the global E{sup 3} model, the impacts of both external and internal drivers are investigated. The ability to connect external and internal drivers through this modeling framework allows the study of impacts and tradeoffs between fossil- versus nuclear-fuel burning, that includes interactions between cost, environmental, proliferation, resource, and policy issues.

  12. Acceleration techniques in the univariate Lipschitz global optimization

    Sergeyev, Yaroslav D.; Kvasov, Dmitri E.; Mukhametzhanov, Marat S.; De Franco, Angela

    2016-10-01

    Univariate box-constrained Lipschitz global optimization problems are considered in this contribution. Geometric and information statistical approaches are presented. The novel powerful local tuning and local improvement techniques are described in the contribution as well as the traditional ways to estimate the Lipschitz constant. The advantages of the presented local tuning and local improvement techniques are demonstrated using the operational characteristics approach for comparing deterministic global optimization algorithms on the class of 100 widely used test functions.

  13. Global optimization of silicon nanowires for efficient parametric processes

    Vukovic, Dragana; Xu, Jing; Mørk, Jesper

    2013-01-01

    We present a global optimization of silicon nanowires for parametric single-pump mixing. For the first time, the effect of surface roughness-induced loss is included in the analysis, significantly influencing the optimum waveguide dimensions.......We present a global optimization of silicon nanowires for parametric single-pump mixing. For the first time, the effect of surface roughness-induced loss is included in the analysis, significantly influencing the optimum waveguide dimensions....

  14. Postponement in logistics strategies of global supply chains

    Agnieszka Szmelter

    2015-12-01

    Full Text Available The paper aims to present postponement strategy as a crucial element of logistics strategies of today’s global supply chains. The article presents the history of postponement, characteristics of this concept, types of postponement and important information about its implementation in global supply chains. The paper also contains guidelines for future research on postponement concept.

  15. What are the Essential Success Strategies for Global CIOs?

    Jay Crotts

    2010-01-01

    @@ As a CIO in the global environment,my biggest challenge is to understand the dynamics of how my company operates in each country.Acquiring an understanding of how market maturity affects business strategy helps me develop an IT strategy that supports local markets while enhancing them with the global resources,processes and efficiencies at our disposal.

  16. Cloud Particles Differential Evolution Algorithm: A Novel Optimization Method for Global Numerical Optimization

    Wei Li

    2015-01-01

    Full Text Available We propose a new optimization algorithm inspired by the formation and change of the cloud in nature, referred to as Cloud Particles Differential Evolution (CPDE algorithm. The cloud is assumed to have three states in the proposed algorithm. Gaseous state represents the global exploration. Liquid state represents the intermediate process from the global exploration to the local exploitation. Solid state represents the local exploitation. The best solution found so far acts as a nucleus. In gaseous state, the nucleus leads the population to explore by condensation operation. In liquid state, cloud particles carry out macrolocal exploitation by liquefaction operation. A new mutation strategy called cloud differential mutation is introduced in order to solve a problem that the misleading effect of a nucleus may cause the premature convergence. In solid state, cloud particles carry out microlocal exploitation by solidification operation. The effectiveness of the algorithm is validated upon different benchmark problems. The results have been compared with eight well-known optimization algorithms. The statistical analysis on performance evaluation of the different algorithms on 10 benchmark functions and CEC2013 problems indicates that CPDE attains good performance.

  17. The Mutual Impact of Global Strategy and Organizational Learning

    Hotho, Jasper J.; Lyles, Marjorie A.; Easterby-Smith, Mark

    2015-01-01

    Despite the interest in issues of knowing and learning in the global strategy field, there has been limited mutual engagement and interaction between the fields of global strategy and organizational learning. The purpose of our article is to reflect on and articulate how the mutual exchange...... of ideas between these fields can be encouraged. To this end, we first conduct a review of the intersection of the fields of global strategy and organizational learning. We then present two recommendations regarding how the interaction between the two fields can be enhanced. Our first recommendation...... is for global strategy research to adopt a broader notion of organizational learning. Our second recommendation is for global strategy research to capitalize on its attention to context in order to inform and enhance organizational learning theory. We discuss the use of context in a number of common research...

  18. Optimal energy management strategy for self-reconfigurable batteries

    Bouchhima, Nejmeddine; Schnierle, Marc; Schulte, Sascha; Birke, Kai Peter

    2017-01-01

    This paper proposes a novel energy management strategy for multi-cell high voltage batteries where the current through each cell can be controlled, called self-reconfigurable batteries. An optimized control strategy further enhances the energy efficiency gained by the hardware architecture of those batteries. Currently, achieving cell equalization by using the active balancing circuits is considered as the best way to optimize the energy efficiency of the battery pack. This study demonstrates that optimizing the energy efficiency of self-reconfigurable batteries is no more strongly correlated to the cell balancing. According to the features of this novel battery architecture, the energy management strategy is formulated as nonlinear dynamic optimization problem. To solve this optimal control, an optimization algorithm that generates the optimal discharge policy for a given driving cycle is developed based on dynamic programming and code vectorization. The simulation results show that the designed energy management strategy maximizes the system efficiency across the battery lifetime over conventional approaches. Furthermore, the present energy management strategy can be implemented online due to the reduced complexity of the optimization algorithm. - Highlights: • The energy efficiency of self-reconfigurable batteries is maximized. • The energy management strategy for the battery is formulated as optimal control problem. • Developing an optimization algorithm using dynamic programming techniques and code vectorization. • Simulation studies are conducted to validate the proposed optimal strategy.

  19. Singapore's Global Schoolhouse Strategy: Retreat or Recalibration?

    Waring, Peter

    2014-01-01

    In 2002 a high-level economic review committee recommended that Singapore position itself as a "global schoolhouse". An ambitious target was set to attract 150,000 international students to Singapore by 2015 and to lift the education sector's contribution to GDP from 1.9% to 5% in the same timeframe. The global schoolhouse was viewed as…

  20. Strategies for mitigation of global warming

    Meyer, Niels I

    2009-01-01

    The paper analyses the international negotions on climate change leading up to COP15 in Copenhagen. Supplementary policies for mitigation of global warming are proposed.......The paper analyses the international negotions on climate change leading up to COP15 in Copenhagen. Supplementary policies for mitigation of global warming are proposed....

  1. Global optimization framework for solar building design

    Silva, N.; Alves, N.; Pascoal-Faria, P.

    2017-07-01

    The generative modeling paradigm is a shift from static models to flexible models. It describes a modeling process using functions, methods and operators. The result is an algorithmic description of the construction process. Each evaluation of such an algorithm creates a model instance, which depends on its input parameters (width, height, volume, roof angle, orientation, location). These values are normally chosen according to aesthetic aspects and style. In this study, the model's parameters are automatically generated according to an objective function. A generative model can be optimized according to its parameters, in this way, the best solution for a constrained problem is determined. Besides the establishment of an overall framework design, this work consists on the identification of different building shapes and their main parameters, the creation of an algorithmic description for these main shapes and the formulation of the objective function, respecting a building's energy consumption (solar energy, heating and insulation). Additionally, the conception of an optimization pipeline, combining an energy calculation tool with a geometric scripting engine is presented. The methods developed leads to an automated and optimized 3D shape generation for the projected building (based on the desired conditions and according to specific constrains). The approach proposed will help in the construction of real buildings that account for less energy consumption and for a more sustainable world.

  2. A kind of balance between exploitation and exploration on kriging for global optimization of expensive functions

    Dong, Huachao; Song, Baowei; Wang, Peng; Huang, Shuai

    2015-01-01

    In this paper, a novel kriging-based algorithm for global optimization of computationally expensive black-box functions is presented. This algorithm utilizes a multi-start approach to find all of the local optimal values of the surrogate model and performs searches within the neighboring area around these local optimal positions. Compared with traditional surrogate-based global optimization method, this algorithm provides another kind of balance between exploitation and exploration on kriging-based model. In addition, a new search strategy is proposed and coupled into this optimization process. The local search strategy employs a kind of improved 'Minimizing the predictor' method, which dynamically adjusts search direction and radius until finds the optimal value. Furthermore, the global search strategy utilizes the advantage of kriging-based model in predicting unexplored regions to guarantee the reliability of the algorithm. Finally, experiments on 13 test functions with six algorithms are set up and the results show that the proposed algorithm is very promising.

  3. WFH: closing the global gap--achieving optimal care.

    Skinner, Mark W

    2012-07-01

    For 50 years, the World Federation of Hemophilia (WFH) has been working globally to close the gap in care and to achieve Treatment for All patients, men and women, with haemophilia and other inherited bleeding disorders, regardless of where they might live. The WFH estimates that more than one in 1000 men and women has a bleeding disorder equating to 6,900,000 worldwide. To close the gap in care between developed and developing nations a continued focus on the successful strategies deployed heretofore will be required. However, in response to the rapid advances in treatment and emerging therapeutic advances on the horizon it will also require fresh approaches and renewed strategic thinking. It is difficult to predict what each therapeutic advance on the horizon will mean for the future, but there is no doubt that we are in a golden age of research and development, which has the prospect of revolutionizing treatment once again. An improved understanding of "optimal" treatment is fundamental to the continued evolution of global care. The challenges of answering government and payer demands for evidence-based medicine, and cost justification for the introduction and enhancement of treatment, are ever-present and growing. To sustain and improve care it is critical to build the body of outcome data for individual patients, within haemophilia treatment centers (HTCs), nationally, regionally and globally. Emerging therapeutic advances (longer half-life therapies and gene transfer) should not be justified or brought to market based only on the notion that they will be economically more affordable, although that may be the case, but rather more importantly that they will be therapeutically more advantageous. Improvements in treatment adherence, reductions in bleeding frequency (including microhemorrhages), better management of trough levels, and improved health outcomes (including quality of life) should be the foremost considerations. As part of a new WFH strategic plan

  4. Toward an Integrative Model of Global Business Strategy

    Li, Xin

    fragmentation-integration-fragmentation-integration upward spiral. In response to the call for integrative approach to strategic management research, we propose an integrative model of global business strategy that aims at integrating not only strategy and IB but also the different paradigms within the strategy...... field. We also discuss the merit and limitation of our model....

  5. The Military Strategy of Global Jihad

    Zabel, Sara E

    2007-01-01

    .... Global jihadis have spent more than 40 years refining their philosophy, gaining experience, building their organization, and developing plans to reestablish what they see as the only true Islamic state on earth...

  6. Innovation Strategies for a Global Economy: Development ...

    2010-10-01

    Oct 1, 2010 ... This path-breaking book integrates theory, case studies, data and policy ... their development, implementation, measurement and management. Following the global economic crisis, people are asking: what went wrong? Here ...

  7. Optimization strategies for ultrasound volume registration

    Ijaz, Umer Zeeshan; Prager, Richard W; Gee, Andrew H; Treece, Graham M

    2010-01-01

    This paper considers registration of 3D ultrasound volumes acquired in multiple views for display in a single image volume. One way to acquire 3D data is to use a mechanically swept 3D probe. However, the usefulness of these probes is restricted by their limited field of view. This problem can be overcome by attaching a six-degree-of-freedom (DOF) position sensor to the probe, and displaying the information from multiple sweeps in their proper positions. However, an external six-DOF position sensor can be an inconvenience in a clinical setting. The objective of this paper is to propose a hybrid strategy that replaces the sensor with a combination of three-DOF image registration and an unobtrusive inertial sensor for measuring orientation. We examine a range of optimization algorithms and similarity measures for registration and compare them in in vitro and in vivo experiments. We register based on multiple reslice images rather than a whole voxel array. In this paper, we use a large number of reslices for improved reliability at the expense of computational speed. We have found that the Levenberg–Marquardt method is very fast but is not guaranteed to give the correct solution all the time. We conclude that normalized mutual information used in the Nelder–Mead simplex algorithm is potentially suitable for the registration task with an average execution time of around 5 min, in the majority of cases, with two restarts in a C++ implementation on a 3.0 GHz Intel Core 2 Duo CPU machine

  8. Optimizing metapopulation sustainability through a checkerboard strategy.

    Yossi Ben Zion

    2010-01-01

    Full Text Available The persistence of a spatially structured population is determined by the rate of dispersal among habitat patches. If the local dynamic at the subpopulation level is extinction-prone, the system viability is maximal at intermediate connectivity where recolonization is allowed, but full synchronization that enables correlated extinction is forbidden. Here we developed and used an algorithm for agent-based simulations in order to study the persistence of a stochastic metapopulation. The effect of noise is shown to be dramatic, and the dynamics of the spatial population differs substantially from the predictions of deterministic models. This has been validated for the stochastic versions of the logistic map, the Ricker map and the Nicholson-Bailey host-parasitoid system. To analyze the possibility of extinction, previous studies were focused on the attractiveness (Lyapunov exponent of stable solutions and the structure of their basin of attraction (dependence on initial population size. Our results suggest that these features are of secondary importance in the presence of stochasticity. Instead, optimal sustainability is achieved when decoherence is maximal. Individual-based simulations of metapopulations of different sizes, dimensions and noise types, show that the system's lifetime peaks when it displays checkerboard spatial patterns. This conclusion is supported by the results of a recently published Drosophila experiment. The checkerboard strategy provides a technique for the manipulation of migration rates (e.g., by constructing corridors in order to affect the persistence of a metapopulation. It may be used in order to minimize the risk of extinction of an endangered species, or to maximize the efficiency of an eradication campaign.

  9. Developing an Integrated Design Strategy for Chip Layout Optimization

    Wits, Wessel Willems; Jauregui Becker, Juan Manuel; van Vliet, Frank Edward; te Riele, G.J.

    2011-01-01

    This paper presents an integrated design strategy for chip layout optimization. The strategy couples both electric and thermal aspects during the conceptual design phase to improve chip performances; thermal management being one of the major topics. The layout of the chip circuitry is optimized

  10. Optimal Spatial Harvesting Strategy and Symmetry-Breaking

    Kurata, Kazuhiro; Shi Junping

    2008-01-01

    A reaction-diffusion model with logistic growth and constant effort harvesting is considered. By minimizing an intrinsic biological energy function, we obtain an optimal spatial harvesting strategy which will benefit the population the most. The symmetry properties of the optimal strategy are also discussed, and related symmetry preserving and symmetry breaking phenomena are shown with several typical examples of habitats

  11. Synthesis of Optimal Strategies Using HyTech

    Bouyer, Patricia; Cassez, Franck; Larsen, Kim Guldstrand

    2005-01-01

    Priced timed (game) automata extend timed (game) automata with costs on both locations and transitions. The problem of synthesizing an optimal winning strategy for a priced timed game under some hypotheses has been shown decidable in [P. Bouyer, F. Cassez, E. Fleury, and K.G. Larsen. Optimal...... strategies in priced timed game automata. Research Report BRICS RS-04-4, Denmark, Feb. 2004. Available at http://www.brics.dk/RS/04/4/]. In this paper, we present an algorithm for computing the optimal cost and for synthesizing an optimal strategy in case there exists one. We also describe the implementation...

  12. Optimization of Key Parameters of Energy Management Strategy for Hybrid Electric Vehicle Using DIRECT Algorithm

    Jingxian Hao

    2016-11-01

    Full Text Available The rule-based logic threshold control strategy has been frequently used in energy management strategies for hybrid electric vehicles (HEVs owing to its convenience in adjusting parameters, real-time performance, stability, and robustness. However, the logic threshold control parameters cannot usually ensure the best vehicle performance at different driving cycles and conditions. For this reason, the optimization of key parameters is important to improve the fuel economy, dynamic performance, and drivability. In principle, this is a multiparameter nonlinear optimization problem. The logic threshold energy management strategy for an all-wheel-drive HEV is comprehensively analyzed and developed in this study. Seven key parameters to be optimized are extracted. The optimization model of key parameters is proposed from the perspective of fuel economy. The global optimization method, DIRECT algorithm, which has good real-time performance, low computational burden, rapid convergence, is selected to optimize the extracted key parameters globally. The results show that with the optimized parameters, the engine operates more at the high efficiency range resulting into a fuel savings of 7% compared with non-optimized parameters. The proposed method can provide guidance for calibrating the parameters of the vehicle energy management strategy from the perspective of fuel economy.

  13. Optimization Strategies for Hardware-Based Cofactorization

    Loebenberger, Daniel; Putzka, Jens

    We use the specific structure of the inputs to the cofactorization step in the general number field sieve (GNFS) in order to optimize the runtime for the cofactorization step on a hardware cluster. An optimal distribution of bitlength-specific ECM modules is proposed and compared to existing ones. With our optimizations we obtain a speedup between 17% and 33% of the cofactorization step of the GNFS when compared to the runtime of an unoptimized cluster.

  14. Optimizing human activity patterns using global sensitivity analysis.

    Fairchild, Geoffrey; Hickmann, Kyle S; Mniszewski, Susan M; Del Valle, Sara Y; Hyman, James M

    2014-12-01

    Implementing realistic activity patterns for a population is crucial for modeling, for example, disease spread, supply and demand, and disaster response. Using the dynamic activity simulation engine, DASim, we generate schedules for a population that capture regular (e.g., working, eating, and sleeping) and irregular activities (e.g., shopping or going to the doctor). We use the sample entropy (SampEn) statistic to quantify a schedule's regularity for a population. We show how to tune an activity's regularity by adjusting SampEn, thereby making it possible to realistically design activities when creating a schedule. The tuning process sets up a computationally intractable high-dimensional optimization problem. To reduce the computational demand, we use Bayesian Gaussian process regression to compute global sensitivity indices and identify the parameters that have the greatest effect on the variance of SampEn. We use the harmony search (HS) global optimization algorithm to locate global optima. Our results show that HS combined with global sensitivity analysis can efficiently tune the SampEn statistic with few search iterations. We demonstrate how global sensitivity analysis can guide statistical emulation and global optimization algorithms to efficiently tune activities and generate realistic activity patterns. Though our tuning methods are applied to dynamic activity schedule generation, they are general and represent a significant step in the direction of automated tuning and optimization of high-dimensional computer simulations.

  15. Particle swarm optimization based optimal bidding strategy in an ...

    In an electricity market generating companies and large consumers need suitable bidding models to maximize their profits. Therefore, each supplier and large consumer will bid strategically for choosing the bidding coefficients to counter the competitors bidding strategy. In this paper, bidding strategy problem modeled as an ...

  16. DaimlerChrysler - powertrain-strategy. Global requirements - global solutions; DaimlerChrysler - Powertrain-Strategie. Globale Anforderungen - Globale Loesungen

    Mikulic, L. [Mercedes Car Group, DaimlerChrysler AG, Mercedes-Benz Technology Center, Stuttgart (Germany); Lee, R. [DaimlerChrysler Corporation, Auburn Hills, MI (United States)

    2007-07-01

    'Globalization' - few concepts have shaped the last fifteen years like this has. For some it is a synonym for unexpected economic and social revolution, a threatening change in familiar arrangements, whilst others see the coalescence of global structures as, more than anything, a challenge - which, if mastered, offers endless possibilities for success. The challenges facing an automotive manufacturer in a globalized world are of quite a different nature. Not least, the constantly increasing competitive pressure has reduced the number of independent automotive manufacturers, in what is known as the Triad (Europe, Japan and North America), from 42 at the beginning of the 1960's to just 15 today. Also in Europe, consolidation has led, on the one hand, to a reduction in individual brands and on the other, to a number of collaborative projects between companies. Even in the dynamically growing East Asia markets, where the number of independent carmakers is still large, such collaborations have already occurred. In the near future much dynamics can be expected within the two fastest growing markets, China and India. Within these competitive markets, a globally operating company like DaimlerChrysler is faced with new challenges. (orig.)

  17. Global gas strategies: a major player's perspective

    Brown, R.L.

    1996-01-01

    Changes in the world demand for energy and discovery of further reserves of natural gas world-wide mean that the natural gas industry is poised to expand its influence on the global fuel markets. This paper explores the industry's potential for expansion, the need for a dynamic approach to change and a respect for the complexity of market forces. Guidelines for success in expansion are drawn up. The virtues of natural gas in relation to environmental factors and diversity of supply, through pipelines or LNG, are extolled and the industry urged to grasp the challenge of the competitive global market fuels. (UK)

  18. Computational Approaches to Simulation and Optimization of Global Aircraft Trajectories

    Ng, Hok Kwan; Sridhar, Banavar

    2016-01-01

    This study examines three possible approaches to improving the speed in generating wind-optimal routes for air traffic at the national or global level. They are: (a) using the resources of a supercomputer, (b) running the computations on multiple commercially available computers and (c) implementing those same algorithms into NASAs Future ATM Concepts Evaluation Tool (FACET) and compares those to a standard implementation run on a single CPU. Wind-optimal aircraft trajectories are computed using global air traffic schedules. The run time and wait time on the supercomputer for trajectory optimization using various numbers of CPUs ranging from 80 to 10,240 units are compared with the total computational time for running the same computation on a single desktop computer and on multiple commercially available computers for potential computational enhancement through parallel processing on the computer clusters. This study also re-implements the trajectory optimization algorithm for further reduction of computational time through algorithm modifications and integrates that with FACET to facilitate the use of the new features which calculate time-optimal routes between worldwide airport pairs in a wind field for use with existing FACET applications. The implementations of trajectory optimization algorithms use MATLAB, Python, and Java programming languages. The performance evaluations are done by comparing their computational efficiencies and based on the potential application of optimized trajectories. The paper shows that in the absence of special privileges on a supercomputer, a cluster of commercially available computers provides a feasible approach for national and global air traffic system studies.

  19. Fetal DNA: strategies for optimal recovery

    Legler, Tobias J.; Heermann, Klaus-Hinrich; Liu, Zhong; Soussan, Aicha Ait; van der Schoot, C. Ellen

    2008-01-01

    For fetal DNA extraction, in principle each DNA extraction method can be used; however, because most methods have been optimized for genomic DNA from leucocytes, we describe here the methods that have been optimized for the extraction of fetal DNA from maternal plasma and validated for this purpose

  20. Strategies for Optimal Design of Structural Systems

    Enevoldsen, I.; Sørensen, John Dalsgaard

    1992-01-01

    Reliability-based design of structural systems is considered. Especially systems where the reliability model is a series system of parallel systems are analysed. A sensitivity analysis for this class of problems is presented. Direct and sequential optimization procedures to solve the optimization...

  1. An optimal tuning strategy for tidal turbines.

    Vennell, Ross

    2016-11-01

    Tuning wind and tidal turbines is critical to maximizing their power output. Adopting a wind turbine tuning strategy of maximizing the output at any given time is shown to be an extremely poor strategy for large arrays of tidal turbines in channels. This 'impatient-tuning strategy' results in far lower power output, much higher structural loads and greater environmental impacts due to flow reduction than an existing 'patient-tuning strategy' which maximizes the power output averaged over the tidal cycle. This paper presents a 'smart patient tuning strategy', which can increase array output by up to 35% over the existing strategy. This smart strategy forgoes some power generation early in the half tidal cycle in order to allow stronger flows to develop later in the cycle. It extracts enough power from these stronger flows to produce more power from the cycle as a whole than the existing strategy. Surprisingly, the smart strategy can often extract more power without increasing maximum structural loads on the turbines, while also maintaining stronger flows along the channel. This paper also shows that, counterintuitively, for some tuning strategies imposing a cap on turbine power output to limit loads can increase a turbine's average power output.

  2. Strategies for global monitoring of tropical forests

    Raymond L. Czaplewski

    1994-01-01

    The Food and Agricultural Organization (FAO) of the United Nations is conducting a global assessment of tropical forest resources, which will be accomplished by mid-1992. This assessment requires, in part, estimates of the total area of tropical forest cover in 1990 and the rate of change in forest cover between 1980 and 1990. The following are described here: (1) the...

  3. Global powertrains - the GM case; Globale Antriebssysteme - Die Strategie von GM

    Johansson, R.J. [General Motors Powertrain Europe, Turin (Italy)

    2006-07-01

    In today's environment the development of vehicles is confronted with very high customer expectations and legislative restrictions, which can only be fulfilled with a high technological effort and profound know how. These challenges are further increased due to the diversity of markets with regional preferences and increased cost and demand for energy. At the same time it is a principle for General Motors to offer our customers a sustainable and economical individual mobility. The worldwide development strategy of GM powertrain is following exactly this philosophy: efficient and and cost-effective technologies are being developed for gasoline and diesel engines in order to fulfill all of todays and all prognosed future requirements. Based on this GM has defined it's longterm strategy, the march to zero, which includes alternative propulsion systems with the ultimate goal of the neutral emission vehicle with ensured energy supply. With a unique worldwide development network GM is in an optimal position to take on this challenge. Already today GM is successfully using the synergies of competence centers all over the world for the global development strategy. Modern powertrains are based on a common structure but allow regional adaptation to all markets by using a modular system. This development philosophy is one of the cornerstones for General Motors position as the world's largest carmaker. (orig.)

  4. Particle swarm optimization based optimal bidding strategy in an ...

    user

    A considerable amount of work has also been reported on the game theory applications ... probability distribution function (Song et al, 1999) and as a continuous ..... compared with GA and Monte Carlo method, therefore the bidding strategies.

  5. Application of surrogate-based global optimization to aerodynamic design

    Pérez, Esther

    2016-01-01

    Aerodynamic design, like many other engineering applications, is increasingly relying on computational power. The growing need for multi-disciplinarity and high fidelity in design optimization for industrial applications requires a huge number of repeated simulations in order to find an optimal design candidate. The main drawback is that each simulation can be computationally expensive – this becomes an even bigger issue when used within parametric studies, automated search or optimization loops, which typically may require thousands of analysis evaluations. The core issue of a design-optimization problem is the search process involved. However, when facing complex problems, the high-dimensionality of the design space and the high-multi-modality of the target functions cannot be tackled with standard techniques. In recent years, global optimization using meta-models has been widely applied to design exploration in order to rapidly investigate the design space and find sub-optimal solutions. Indeed, surrogat...

  6. Global Optimization for Bus Line Timetable Setting Problem

    Qun Chen

    2014-01-01

    Full Text Available This paper defines bus timetables setting problem during each time period divided in terms of passenger flow intensity; it is supposed that passengers evenly arrive and bus runs are set evenly; the problem is to determine bus runs assignment in each time period to minimize the total waiting time of passengers on platforms if the number of the total runs is known. For such a multistage decision problem, this paper designed a dynamic programming algorithm to solve it. Global optimization procedures using dynamic programming are developed. A numerical example about bus runs assignment optimization of a single line is given to demonstrate the efficiency of the proposed methodology, showing that optimizing buses’ departure time using dynamic programming can save computational time and find the global optimal solution.

  7. A dynamic global and local combined particle swarm optimization algorithm

    Jiao Bin; Lian Zhigang; Chen Qunxian

    2009-01-01

    Particle swarm optimization (PSO) algorithm has been developing rapidly and many results have been reported. PSO algorithm has shown some important advantages by providing high speed of convergence in specific problems, but it has a tendency to get stuck in a near optimal solution and one may find it difficult to improve solution accuracy by fine tuning. This paper presents a dynamic global and local combined particle swarm optimization (DGLCPSO) algorithm to improve the performance of original PSO, in which all particles dynamically share the best information of the local particle, global particle and group particles. It is tested with a set of eight benchmark functions with different dimensions and compared with original PSO. Experimental results indicate that the DGLCPSO algorithm improves the search performance on the benchmark functions significantly, and shows the effectiveness of the algorithm to solve optimization problems.

  8. Optimal portfolio strategies under a shortfall constraint

    we make precise the optimal control problem to be solved. .... is closely related to the concept of Value-at-Risk, but overcomes some of the conceptual .... We adapt a dynamic programming approach to solve the HJB equation associated with.

  9. Optimal Pricing Strategy for New Products

    Trichy V. Krishnan; Frank M. Bass; Dipak C. Jain

    1999-01-01

    Robinson and Lakhani (1975) initiated a long research stream in marketing when they used the Bass model (1969) to develop optimal pricing path for a new product. A careful analysis of the extant literature reveals that the research predominantly suggests that the optimal price path should be largely based on the sales growth pattern. However, in the real world we rarely find new products that have such pricing pattern. We observe either a monotonically declining pricing pattern or an increase...

  10. An optimal tuning strategy for tidal turbines

    2016-01-01

    Tuning wind and tidal turbines is critical to maximizing their power output. Adopting a wind turbine tuning strategy of maximizing the output at any given time is shown to be an extremely poor strategy for large arrays of tidal turbines in channels. This ‘impatient-tuning strategy’ results in far lower power output, much higher structural loads and greater environmental impacts due to flow reduction than an existing ‘patient-tuning strategy’ which maximizes the power output averaged over the tidal cycle. This paper presents a ‘smart patient tuning strategy’, which can increase array output by up to 35% over the existing strategy. This smart strategy forgoes some power generation early in the half tidal cycle in order to allow stronger flows to develop later in the cycle. It extracts enough power from these stronger flows to produce more power from the cycle as a whole than the existing strategy. Surprisingly, the smart strategy can often extract more power without increasing maximum structural loads on the turbines, while also maintaining stronger flows along the channel. This paper also shows that, counterintuitively, for some tuning strategies imposing a cap on turbine power output to limit loads can increase a turbine’s average power output. PMID:27956870

  11. WHO global and regional strategies for health and environment

    Hisashi Ogawa

    1996-01-01

    This paper describes the WHO global and regional strategies for health and environment and discusses research needs on environmental health to support the implementation of the strategies. Particular emphasis on applied researches which generate information, for decision making, on health effects of development and environmental changes in specific locations

  12. WHO global and regional strategies for health and environment

    Ogawa, Hisashi [World Health Organization, Manila (Philippines). Regional Office for the Western Pacific

    1997-12-31

    This paper describes the WHO global and regional strategies for health and environment and discusses research needs on environmental health to support the implementation of the strategies. Particular emphasis on applied researches which generate information, for decision making, on health effects of development and environmental changes in specific locations.

  13. Global-local optimization of flapping kinematics in hovering flight

    Ghommem, Mehdi; Hajj, M. R.; Mook, Dean T.; Stanford, Bret K.; Bé ran, Philip S.; Watson, Layne T.

    2013-01-01

    The kinematics of a hovering wing are optimized by combining the 2-d unsteady vortex lattice method with a hybrid of global and local optimization algorithms. The objective is to minimize the required aerodynamic power under a lift constraint. The hybrid optimization is used to efficiently navigate the complex design space due to wing-wake interference present in hovering aerodynamics. The flapping wing is chosen so that its chord length and flapping frequency match the morphological and flight properties of two insects with different masses. The results suggest that imposing a delay between the different oscillatory motions defining the flapping kinematics, and controlling the way through which the wing rotates at the end of each half stroke can improve aerodynamic power under a lift constraint. Furthermore, our optimization analysis identified optimal kinematics that agree fairly well with observed insect kinematics, as well as previously published numerical results.

  14. Global-local optimization of flapping kinematics in hovering flight

    Ghommem, Mehdi

    2013-06-01

    The kinematics of a hovering wing are optimized by combining the 2-d unsteady vortex lattice method with a hybrid of global and local optimization algorithms. The objective is to minimize the required aerodynamic power under a lift constraint. The hybrid optimization is used to efficiently navigate the complex design space due to wing-wake interference present in hovering aerodynamics. The flapping wing is chosen so that its chord length and flapping frequency match the morphological and flight properties of two insects with different masses. The results suggest that imposing a delay between the different oscillatory motions defining the flapping kinematics, and controlling the way through which the wing rotates at the end of each half stroke can improve aerodynamic power under a lift constraint. Furthermore, our optimization analysis identified optimal kinematics that agree fairly well with observed insect kinematics, as well as previously published numerical results.

  15. Dispositional Optimism and Terminal Decline in Global Quality of Life

    Zaslavsky, Oleg; Palgi, Yuval; Rillamas-Sun, Eileen; LaCroix, Andrea Z.; Schnall, Eliezer; Woods, Nancy F.; Cochrane, Barbara B.; Garcia, Lorena; Hingle, Melanie; Post, Stephen; Seguin, Rebecca; Tindle, Hilary; Shrira, Amit

    2015-01-01

    We examined whether dispositional optimism relates to change in global quality of life (QOL) as a function of either chronological age or years to impending death. We used a sample of 2,096 deceased postmenopausal women from the Women's Health Initiative clinical trials who were enrolled in the 2005-2010 Extension Study and for whom at least 1…

  16. Global integration strategies in times of crisis

    Jensen, Camilla

    2017-01-01

    In recent years, we can observe the emergence of firms, born both digital and global, that have disrupted existing industries. Deploying digital technologies, they have developed innovative value chains and business models that threaten established multinational companies (MNCs). In this chapter......, we examine how MNCs can and do respond to the challenge digital technologies represent. We describe the main facets of digital technologies and discus the potential these have to undermine the value chains and business models of established MNCs. In order to illustrate this, we employ longitudinal...... data from Telenor, a leading multinational mobile telecom company. Telenor perceives digitalization as a critical threat that in turn is causing a radical rethink about the viability of its decentralized, locally responsive value chain and business model. Our data provides insights into business models...

  17. Global Optimization of Nonlinear Blend-Scheduling Problems

    Pedro A. Castillo Castillo

    2017-04-01

    Full Text Available The scheduling of gasoline-blending operations is an important problem in the oil refining industry. This problem not only exhibits the combinatorial nature that is intrinsic to scheduling problems, but also non-convex nonlinear behavior, due to the blending of various materials with different quality properties. In this work, a global optimization algorithm is proposed to solve a previously published continuous-time mixed-integer nonlinear scheduling model for gasoline blending. The model includes blend recipe optimization, the distribution problem, and several important operational features and constraints. The algorithm employs piecewise McCormick relaxation (PMCR and normalized multiparametric disaggregation technique (NMDT to compute estimates of the global optimum. These techniques partition the domain of one of the variables in a bilinear term and generate convex relaxations for each partition. By increasing the number of partitions and reducing the domain of the variables, the algorithm is able to refine the estimates of the global solution. The algorithm is compared to two commercial global solvers and two heuristic methods by solving four examples from the literature. Results show that the proposed global optimization algorithm performs on par with commercial solvers but is not as fast as heuristic approaches.

  18. Global Optimization Based on the Hybridization of Harmony Search and Particle Swarm Optimization Methods

    A. P. Karpenko

    2014-01-01

    Full Text Available We consider a class of stochastic search algorithms of global optimization which in various publications are called behavioural, intellectual, metaheuristic, inspired by the nature, swarm, multi-agent, population, etc. We use the last term.Experience in using the population algorithms to solve challenges of global optimization shows that application of one such algorithm may not always effective. Therefore now great attention is paid to hybridization of population algorithms of global optimization. Hybrid algorithms unite various algorithms or identical algorithms, but with various values of free parameters. Thus efficiency of one algorithm can compensate weakness of another.The purposes of the work are development of hybrid algorithm of global optimization based on known algorithms of harmony search (HS and swarm of particles (PSO, software implementation of algorithm, study of its efficiency using a number of known benchmark problems, and a problem of dimensional optimization of truss structure.We set a problem of global optimization, consider basic algorithms of HS and PSO, give a flow chart of the offered hybrid algorithm called PSO HS , present results of computing experiments with developed algorithm and software, formulate main results of work and prospects of its development.

  19. Power consumption optimization strategy for wireless networks

    Cornean, Horia; Kumar, Sanjay; Marchetti, Nicola

    2011-01-01

    in order to reduce the total power consumption in a multi cellular network. We present an algorithm for power optimization under no interference and in presence of interference conditions, targeting to maximize the network capacity. The convergence of the algorithm is guaranteed if the interference...

  20. An Analysis of Yip's Global Strategy Model, Using Coca-Cola ...

    Analysis of the selected business cases suggest a weak fit between the Yip model of a truly Global strategy ... like Coca-Cola in the beverage industry for effective implementation of a global strategy. ... Keywords: Global Strategy, Leadership.

  1. Global Sufficient Optimality Conditions for a Special Cubic Minimization Problem

    Xiaomei Zhang

    2012-01-01

    Full Text Available We present some sufficient global optimality conditions for a special cubic minimization problem with box constraints or binary constraints by extending the global subdifferential approach proposed by V. Jeyakumar et al. (2006. The present conditions generalize the results developed in the work of V. Jeyakumar et al. where a quadratic minimization problem with box constraints or binary constraints was considered. In addition, a special diagonal matrix is constructed, which is used to provide a convenient method for justifying the proposed sufficient conditions. Then, the reformulation of the sufficient conditions follows. It is worth noting that this reformulation is also applicable to the quadratic minimization problem with box or binary constraints considered in the works of V. Jeyakumar et al. (2006 and Y. Wang et al. (2010. Finally some examples demonstrate that our optimality conditions can effectively be used for identifying global minimizers of the certain nonconvex cubic minimization problem.

  2. Intelligent fault recognition strategy based on adaptive optimized multiple centers

    Zheng, Bo; Li, Yan-Feng; Huang, Hong-Zhong

    2018-06-01

    For the recognition principle based optimized single center, one important issue is that the data with nonlinear separatrix cannot be recognized accurately. In order to solve this problem, a novel recognition strategy based on adaptive optimized multiple centers is proposed in this paper. This strategy recognizes the data sets with nonlinear separatrix by the multiple centers. Meanwhile, the priority levels are introduced into the multi-objective optimization, including recognition accuracy, the quantity of optimized centers, and distance relationship. According to the characteristics of various data, the priority levels are adjusted to ensure the quantity of optimized centers adaptively and to keep the original accuracy. The proposed method is compared with other methods, including support vector machine (SVM), neural network, and Bayesian classifier. The results demonstrate that the proposed strategy has the same or even better recognition ability on different distribution characteristics of data.

  3. Long-run savings and investment strategy optimization.

    Gerrard, Russell; Guillén, Montserrat; Nielsen, Jens Perch; Pérez-Marín, Ana M

    2014-01-01

    We focus on automatic strategies to optimize life cycle savings and investment. Classical optimal savings theory establishes that, given the level of risk aversion, a saver would keep the same relative amount invested in risky assets at any given time. We show that, when optimizing lifecycle investment, performance and risk assessment have to take into account the investor's risk aversion and the maximum amount the investor could lose, simultaneously. When risk aversion and maximum possible loss are considered jointly, an optimal savings strategy is obtained, which follows from constant rather than relative absolute risk aversion. This result is fundamental to prove that if risk aversion and the maximum possible loss are both high, then holding a constant amount invested in the risky asset is optimal for a standard lifetime saving/pension process and outperforms some other simple strategies. Performance comparisons are based on downside risk-adjusted equivalence that is used in our illustration.

  4. Long-Run Savings and Investment Strategy Optimization

    Russell Gerrard

    2014-01-01

    Full Text Available We focus on automatic strategies to optimize life cycle savings and investment. Classical optimal savings theory establishes that, given the level of risk aversion, a saver would keep the same relative amount invested in risky assets at any given time. We show that, when optimizing lifecycle investment, performance and risk assessment have to take into account the investor’s risk aversion and the maximum amount the investor could lose, simultaneously. When risk aversion and maximum possible loss are considered jointly, an optimal savings strategy is obtained, which follows from constant rather than relative absolute risk aversion. This result is fundamental to prove that if risk aversion and the maximum possible loss are both high, then holding a constant amount invested in the risky asset is optimal for a standard lifetime saving/pension process and outperforms some other simple strategies. Performance comparisons are based on downside risk-adjusted equivalence that is used in our illustration.

  5. Optimal inspection strategies for offshore structural systems

    Faber, M. H.; Sorensen, J. D.; Kroon, I. B.

    1992-01-01

    a mathematical framework for the estimation of the failure and repair costs a.ssociated with systems failure. Further a strategy for selecting the components to inspect based on decision tree analysis is suggested. Methods and analysis schemes are illustrated by a simple example....

  6. Antimicrobial stewardship: Strategies for a global response

    Jenny Grunwald

    2014-01-01

    Full Text Available The increasing antimicrobial resistance worldwide, combined with dwindling antimicrobial armamentarium, has resulted in a critical threat to the public health and safety of patients. To combat this hazard, antimicrobial stewardship programs (ASPs have emerged. Antimicrobial stewardship programs prevent or slow the emergence of antimicrobial resistance by coordinated interventions designed to optimize antimicrobial use to achieve the best clinical outcomes and limiting selective pressures that drive the emergence of resistance. This also reduces excessive costs attributable to suboptimal antimicrobial use. Even though an ideal effective ASP should incorporate more than one element simultaneously, it also requires a multidisciplinary team, which should include an infectious diseases physician, a clinical pharmacist with infectious diseases training, infection control professionals, hospital epidemiologist, a clinical microbiologist and an information specialist. However, for antimicrobial stewardship (AMS programs to be successful, they must address the specific needs of individual institutions, must be built on available resources, the limitations and advantages of each institution, and the available staffing and technological infrastructure.

  7. Control strategy optimization of HVAC plants

    Facci, Andrea Luigi; Zanfardino, Antonella [Department of Engineering, University of Napoli “Parthenope” (Italy); Martini, Fabrizio [Green Energy Plus srl (Italy); Pirozzi, Salvatore [SIAT Installazioni spa (Italy); Ubertini, Stefano [School of Engineering (DEIM) University of Tuscia (Italy)

    2015-03-10

    In this paper we present a methodology to optimize the operating conditions of heating, ventilation and air conditioning (HVAC) plants to achieve a higher energy efficiency in use. Semi-empiric numerical models of the plant components are used to predict their performances as a function of their set-point and the environmental and occupied space conditions. The optimization is performed through a graph-based algorithm that finds the set-points of the system components that minimize energy consumption and/or energy costs, while matching the user energy demands. The resulting model can be used with systems of almost any complexity, featuring both HVAC components and energy systems, and is sufficiently fast to make it applicable to real-time setting.

  8. Control strategy optimization of HVAC plants

    Facci, Andrea Luigi; Zanfardino, Antonella; Martini, Fabrizio; Pirozzi, Salvatore; Ubertini, Stefano

    2015-01-01

    In this paper we present a methodology to optimize the operating conditions of heating, ventilation and air conditioning (HVAC) plants to achieve a higher energy efficiency in use. Semi-empiric numerical models of the plant components are used to predict their performances as a function of their set-point and the environmental and occupied space conditions. The optimization is performed through a graph-based algorithm that finds the set-points of the system components that minimize energy consumption and/or energy costs, while matching the user energy demands. The resulting model can be used with systems of almost any complexity, featuring both HVAC components and energy systems, and is sufficiently fast to make it applicable to real-time setting

  9. Optimal Licensing Strategy: Royalty or Fixed Fee?

    Andrea Fosfuri; Esther Roca

    2004-01-01

    Licensing a cost-reducing innovation through a royalty has been shown to be superior to licensing by means of a fixed fee for an incumbent licensor. This note shows that this result relies crucially on the assumption that the incumbent licensor can sell its cost-reducing inno-vation to all industry players. If, for any reason, only some competitors could be reached through a licensing contract, then a fixed fee might be optimally chosen.

  10. Optimized Power Dispatch Strategy for Offshore Wind Farms

    Hou, Peng; Hu, Weihao; Zhang, Baohua

    2016-01-01

    which are related to electrical system topology. This paper proposed an optimized power dispatch strategy (OPD) for minimizing the levelized production cost (LPC) of a wind farm. Particle swarm optimization (PSO) is employed to obtain final solution for the optimization problem. Both regular shape......Maximizing the power production of offshore wind farms using proper control strategy has become an important issue for wind farm operators. However, the power transmitted to the onshore substation (OS) is not only related to the power production of each wind turbine (WT) but also the power losses...... and irregular shape wind farm are chosen for the case study. The proposed dispatch strategy is compared with two other control strategies. The simulation results show the effectiveness of the proposed strategy....

  11. Sleep As A Strategy For Optimizing Performance.

    Yarnell, Angela M; Deuster, Patricia

    2016-01-01

    Recovery is an essential component of maintaining, sustaining, and optimizing cognitive and physical performance during and after demanding training and strenuous missions. Getting sufficient amounts of rest and sleep is key to recovery. This article focuses on sleep and discusses (1) why getting sufficient sleep is important, (2) how to optimize sleep, and (3) tools available to help maximize sleep-related performance. Insufficient sleep negatively impacts safety and readiness through reduced cognitive function, more accidents, and increased military friendly-fire incidents. Sufficient sleep is linked to better cognitive performance outcomes, increased vigor, and better physical and athletic performance as well as improved emotional and social functioning. Because Special Operations missions do not always allow for optimal rest or sleep, the impact of reduced rest and sleep on readiness and mission success should be minimized through appropriate preparation and planning. Preparation includes periods of "banking" or extending sleep opportunities before periods of loss, monitoring sleep by using tools like actigraphy to measure sleep and activity, assessing mental effectiveness, exploiting strategic sleep opportunities, and consuming caffeine at recommended doses to reduce fatigue during periods of loss. Together, these efforts may decrease the impact of sleep loss on mission and performance. 2016.

  12. Optimal Dynamic Advertising Strategy Under Age-Specific Market Segmentation

    Krastev, Vladimir

    2011-12-01

    We consider the model proposed by Faggian and Grosset for determining the advertising efforts and goodwill in the long run of a company under age segmentation of consumers. Reducing this model to optimal control sub problems we find the optimal advertising strategy and goodwill.

  13. A strategy for optimizing item-pool management

    Ariel, A.; van der Linden, Willem J.; Veldkamp, Bernard P.

    2006-01-01

    Item-pool management requires a balancing act between the input of new items into the pool and the output of tests assembled from it. A strategy for optimizing item-pool management is presented that is based on the idea of a periodic update of an optimal blueprint for the item pool to tune item

  14. Neoliberal Optimism: Applying Market Techniques to Global Health.

    Mei, Yuyang

    2017-01-01

    Global health and neoliberalism are becoming increasingly intertwined as organizations utilize markets and profit motives to solve the traditional problems of poverty and population health. I use field work conducted over 14 months in a global health technology company to explore how the promise of neoliberalism re-envisions humanitarian efforts. In this company's vaccine refrigerator project, staff members expect their investors and their market to allow them to achieve scale and develop accountability to their users in developing countries. However, the translation of neoliberal techniques to the global health sphere falls short of the ideal, as profits are meager and purchasing power remains with donor organizations. The continued optimism in market principles amidst such a non-ideal market reveals the tenacious ideological commitment to neoliberalism in these global health projects.

  15. Blind Channel Equalization Using Constrained Generalized Pattern Search Optimization and Reinitialization Strategy

    Charles Tatkeu

    2008-12-01

    Full Text Available We propose a global convergence baud-spaced blind equalization method in this paper. This method is based on the application of both generalized pattern optimization and channel surfing reinitialization. The potentially used unimodal cost function relies on higher- order statistics, and its optimization is achieved using a pattern search algorithm. Since the convergence to the global minimum is not unconditionally warranted, we make use of channel surfing reinitialization (CSR strategy to find the right global minimum. The proposed algorithm is analyzed, and simulation results using a severe frequency selective propagation channel are given. Detailed comparisons with constant modulus algorithm (CMA are highlighted. The proposed algorithm performances are evaluated in terms of intersymbol interference, normalized received signal constellations, and root mean square error vector magnitude. In case of nonconstant modulus input signals, our algorithm outperforms significantly CMA algorithm with full channel surfing reinitialization strategy. However, comparable performances are obtained for constant modulus signals.

  16. Blind Channel Equalization Using Constrained Generalized Pattern Search Optimization and Reinitialization Strategy

    Zaouche, Abdelouahib; Dayoub, Iyad; Rouvaen, Jean Michel; Tatkeu, Charles

    2008-12-01

    We propose a global convergence baud-spaced blind equalization method in this paper. This method is based on the application of both generalized pattern optimization and channel surfing reinitialization. The potentially used unimodal cost function relies on higher- order statistics, and its optimization is achieved using a pattern search algorithm. Since the convergence to the global minimum is not unconditionally warranted, we make use of channel surfing reinitialization (CSR) strategy to find the right global minimum. The proposed algorithm is analyzed, and simulation results using a severe frequency selective propagation channel are given. Detailed comparisons with constant modulus algorithm (CMA) are highlighted. The proposed algorithm performances are evaluated in terms of intersymbol interference, normalized received signal constellations, and root mean square error vector magnitude. In case of nonconstant modulus input signals, our algorithm outperforms significantly CMA algorithm with full channel surfing reinitialization strategy. However, comparable performances are obtained for constant modulus signals.

  17. Solving Unconstrained Global Optimization Problems via Hybrid Swarm Intelligence Approaches

    Jui-Yu Wu

    2013-01-01

    Full Text Available Stochastic global optimization (SGO algorithms such as the particle swarm optimization (PSO approach have become popular for solving unconstrained global optimization (UGO problems. The PSO approach, which belongs to the swarm intelligence domain, does not require gradient information, enabling it to overcome this limitation of traditional nonlinear programming methods. Unfortunately, PSO algorithm implementation and performance depend on several parameters, such as cognitive parameter, social parameter, and constriction coefficient. These parameters are tuned by using trial and error. To reduce the parametrization of a PSO method, this work presents two efficient hybrid SGO approaches, namely, a real-coded genetic algorithm-based PSO (RGA-PSO method and an artificial immune algorithm-based PSO (AIA-PSO method. The specific parameters of the internal PSO algorithm are optimized using the external RGA and AIA approaches, and then the internal PSO algorithm is applied to solve UGO problems. The performances of the proposed RGA-PSO and AIA-PSO algorithms are then evaluated using a set of benchmark UGO problems. Numerical results indicate that, besides their ability to converge to a global minimum for each test UGO problem, the proposed RGA-PSO and AIA-PSO algorithms outperform many hybrid SGO algorithms. Thus, the RGA-PSO and AIA-PSO approaches can be considered alternative SGO approaches for solving standard-dimensional UGO problems.

  18. Blackjack in Holland Casino's : Basic, optimal and winning strategies

    van der Genugten, B.B.

    1995-01-01

    This paper considers the cardgame Blackjack according to the rules of Holland Casino's in the Netherlands. Expected gains of strategies are derived with simulation and also with analytic tools. New effiency concepts based on the gains of the basic and the optimal strategy are introduced. A general

  19. Selective Segmentation for Global Optimization of Depth Estimation in Complex Scenes

    Sheng Liu

    2013-01-01

    Full Text Available This paper proposes a segmentation-based global optimization method for depth estimation. Firstly, for obtaining accurate matching cost, the original local stereo matching approach based on self-adapting matching window is integrated with two matching cost optimization strategies aiming at handling both borders and occlusion regions. Secondly, we employ a comprehensive smooth term to satisfy diverse smoothness request in real scene. Thirdly, a selective segmentation term is used for enforcing the plane trend constraints selectively on the corresponding segments to further improve the accuracy of depth results from object level. Experiments on the Middlebury image pairs show that the proposed global optimization approach is considerably competitive with other state-of-the-art matching approaches.

  20. Priority setting of strategies and mechanisms for limiting global warming

    Lewis, S.J.L.

    1994-01-01

    Scientific communities have reached a consensus that increases of greenhouse gas emission will result in climatic warming and sea level rises despite existing uncertainties. Major uncertainties include the sensitivities of climate changes in terms of timing, magnitude, and scales of regional changes. Socioeconomic uncertainties encompass population and economic growth, changes in technology, future reliance on fossil fuel, and policies compiled to stabilize the global warming. Moreover, increase in world population coupled with limited resources will increase the vulnerability of ecosystems and social systems. Global warming has become an international concern since the destinies of all nations are closely interwoven by this issue and how nations deal with it. Appropriate strategies and mechanisms are need to slow down the buildup of CO 2 and other greenhouse gases. Questionnaires were sent to 150 experts in 30 countries to evaluate such strategies and mechanisms for dealing with global warming, from both the domestic and international perspectives. This paper will focus primarily on strategy selection

  1. The Islamic State’s Global Propaganda Strategy

    Daveed Gartenstein-Ross

    2016-03-01

    Full Text Available This Research Paper aims to analyse in depth the global propaganda strategy of the so-called “Islamic State” (IS by looking at the methods through which this grand strategy is carried out as well as the objectives that IS wants to achieve through it. The authors first discuss IS’ growth model, explaining why global expansion and recruitment of foreign fighters are pivotal to IS success. Having in mind this critical role, the authors then explore the narratives and themes used by the group to mobilise foreign fighters and jihadists groups. Third, the paper analyses how IS deploys its narratives in those territories where it has established a foothold. Fourth, it outlines IS’ direct engagement strategy and how it is used to facilitate allegiance of other jihadist groups. The final section of the paper offers a menu of policy options that stakeholders can implement to counter IS’ global propaganda efforts.

  2. Hydrogen energy strategies and global stability and unrest

    Midilli, A.; Dincer, I.; Rosen, M.A.

    2004-01-01

    This paper focuses on hydrogen energy strategies and global stability and unrest. In order to investigate the strategic relationship between these concepts, two empirical relations that describe the effects of fossil fuels on global stability and global unrest are developed. These relations incorporate predicted utilization ratios for hydrogen energy from non-fossil fuels, and are used to investigate whether hydrogen utilization can reduce the negative global effects related to fossil fuel use, eliminate or reduce the possibilities of global energy conflicts, and contribute to achieving world stability. It is determined that, if utilization of hydrogen from non-fossil fuels increases, for a fixed usage of petroleum, coal and natural gas, the level of global unrest decreases. However, if the utilization ratio of hydrogen energy from non-fossil fuels is lower than 100%, the level of global stability decreases as the symptoms of global unrest increase. It is suggested that, to reduce the causes of global unrest and increase the likelihood of global stability in the future, hydrogen energy should be widely and efficiently used, as one component of plans for sustainable development. (author)

  3. An Optimal Method for Developing Global Supply Chain Management System

    Hao-Chun Lu

    2013-01-01

    Full Text Available Owing to the transparency in supply chains, enhancing competitiveness of industries becomes a vital factor. Therefore, many developing countries look for a possible method to save costs. In this point of view, this study deals with the complicated liberalization policies in the global supply chain management system and proposes a mathematical model via the flow-control constraints, which are utilized to cope with the bonded warehouses for obtaining maximal profits. Numerical experiments illustrate that the proposed model can be effectively solved to obtain the optimal profits in the global supply chain environment.

  4. A new inertia weight control strategy for particle swarm optimization

    Zhu, Xianming; Wang, Hongbo

    2018-04-01

    Particle Swarm Optimization is a member of swarm intelligence algorithms, which is inspired by the behavior of bird flocks. The inertia weight, one of the most important parameters of PSO, is crucial for PSO, for it balances the performance of exploration and exploitation of the algorithm. This paper proposes a new inertia weight control strategy and PSO with this new strategy is tested by four benchmark functions. The results shows that the new strategy provides the PSO with better performance.

  5. GLOBAL OPTIMIZATION METHODS FOR GRAVITATIONAL LENS SYSTEMS WITH REGULARIZED SOURCES

    Rogers, Adam; Fiege, Jason D.

    2012-01-01

    Several approaches exist to model gravitational lens systems. In this study, we apply global optimization methods to find the optimal set of lens parameters using a genetic algorithm. We treat the full optimization procedure as a two-step process: an analytical description of the source plane intensity distribution is used to find an initial approximation to the optimal lens parameters; the second stage of the optimization uses a pixelated source plane with the semilinear method to determine an optimal source. Regularization is handled by means of an iterative method and the generalized cross validation (GCV) and unbiased predictive risk estimator (UPRE) functions that are commonly used in standard image deconvolution problems. This approach simultaneously estimates the optimal regularization parameter and the number of degrees of freedom in the source. Using the GCV and UPRE functions, we are able to justify an estimation of the number of source degrees of freedom found in previous work. We test our approach by applying our code to a subset of the lens systems included in the SLACS survey.

  6. Global Optimization of Minority Game by Smart Agents

    Yan-Bo Xie; Bing-Hong Wang; Chin-Kun Hu; Tao Zhou

    2004-01-01

    We propose a new model of minority game with so-called smart agents such that the standard deviation and the total loss in this model reach the theoretical minimum values in the limit of long time. The smart agents use trail and error method to make a choice but bring global optimization to the system, which suggests that the economic systems may have the ability to self-organize into a highly optimized state by agents who are forced to make decisions based on inductive thinking for their lim...

  7. Noise-dependent optimal strategies for quantum metrology

    Huang, Zixin; Macchiavello, Chiara; Maccone, Lorenzo

    2018-03-01

    For phase estimation using qubits, we show that for some noise channels, the optimal entanglement-assisted strategy depends on the noise level. We note that there is a nontrivial crossover between the parallel-entangled strategy and the ancilla-assisted strategy: in the former the probes are all entangled; in the latter the probes are entangled with a noiseless ancilla but not among themselves. The transition can be explained by the fact that separable states are more robust against noise and therefore are optimal in the high-noise limit, but they are in turn outperformed by ancilla-assisted ones.

  8. Digital Innovations: Startup Marketing Strategy for Global Growth

    Gröhn, Hanna

    2017-01-01

    This thesis discusses the relatively new phenomena of innovative digital products created by startup companies, who often must scale globally fast, before the volatile trends or the fierce competition of the digital marketspace take over. International entry itself is no longer the issue, but rather standing out in the crowd while balancing resources and flexibility. The focus is on how startups can induce global growth and tackle structural obstacles by means of marketing strategy. The t...

  9. Optimal intermittent search strategies: smelling the prey

    Revelli, J A; Wio, H S; Rojo, F; Budde, C E

    2010-01-01

    We study the kinetics of the search of a single fixed target by a searcher/walker that performs an intermittent random walk, characterized by different states of motion. In addition, we assume that the walker has the ability to detect the scent left by the prey/target in its surroundings. Our results, in agreement with intuition, indicate that the prey's survival probability could be strongly reduced (increased) if the predator is attracted (or repelled) by the trace left by the prey. We have also found that, for a positive trace (the predator is guided towards the prey), increasing the inhomogeneity's size reduces the prey's survival probability, while the optimal value of α (the parameter that regulates intermittency) ceases to exist. The agreement between theory and numerical simulations is excellent.

  10. Optimal intermittent search strategies: smelling the prey

    Revelli, J A; Wio, H S [Instituto de Fisica de Cantabria, Universidad de Cantabria and CSIC, E-39005 Santander (Spain); Rojo, F; Budde, C E [Fa.M.A.F., Universidad Nacional de Cordoba, Ciudad Universitaria, X5000HUA Cordoba (Argentina)

    2010-05-14

    We study the kinetics of the search of a single fixed target by a searcher/walker that performs an intermittent random walk, characterized by different states of motion. In addition, we assume that the walker has the ability to detect the scent left by the prey/target in its surroundings. Our results, in agreement with intuition, indicate that the prey's survival probability could be strongly reduced (increased) if the predator is attracted (or repelled) by the trace left by the prey. We have also found that, for a positive trace (the predator is guided towards the prey), increasing the inhomogeneity's size reduces the prey's survival probability, while the optimal value of {alpha} (the parameter that regulates intermittency) ceases to exist. The agreement between theory and numerical simulations is excellent.

  11. Optimal Inspection and Maintenance Strategies for Structural Systems

    Sommer, A. M.

    The aim of this thesis is to give an overview of conventional and optimal reliability-based inspection and maintenance strategies and to examine for specific structures how the cost can be reduced and/or the safety can be improved by using optimal reliability-based inspection strategies....... For structures with several almost similar components it is suggested that individual inspection strategies should be determined for each component or a group of components based on the reliability of the actual component. The benefit of this procedure is assessed in connection with the structures considered....... Furthermore, in relation to the calculations performed the intention is to modify an existing program for determination of optimal inspection strategies. The main purpose of inspection and maintenance of structural systems is to prevent or delay damage or deterioration to protect people, environment...

  12. Malaysian diaspora strategies in a globalized Muslim market

    Fischer, Johan

    2015-01-01

    This paper explores Malaysia’s efforts to develop and dominate a global market in halal (literally, ‘lawful or ‘permitted’) commodities as a diaspora strategy and how Malaysian state institutions, entrepreneurs, restaurants and middle-class groups in London respond to and are affected...... and practise Malaysian diaspora strategies in the globalized market for halal products and services. This paper is based on ethnographic material from fieldwork among state institutions, entrepreneurs, restaurants and middle-class groups in Kuala Lumpur and London, namely participant observation...

  13. An Algorithm for Global Optimization Inspired by Collective Animal Behavior

    Erik Cuevas

    2012-01-01

    Full Text Available A metaheuristic algorithm for global optimization called the collective animal behavior (CAB is introduced. Animal groups, such as schools of fish, flocks of birds, swarms of locusts, and herds of wildebeest, exhibit a variety of behaviors including swarming about a food source, milling around a central locations, or migrating over large distances in aligned groups. These collective behaviors are often advantageous to groups, allowing them to increase their harvesting efficiency, to follow better migration routes, to improve their aerodynamic, and to avoid predation. In the proposed algorithm, the searcher agents emulate a group of animals which interact with each other based on the biological laws of collective motion. The proposed method has been compared to other well-known optimization algorithms. The results show good performance of the proposed method when searching for a global optimum of several benchmark functions.

  14. A Globally Convergent Parallel SSLE Algorithm for Inequality Constrained Optimization

    Zhijun Luo

    2014-01-01

    Full Text Available A new parallel variable distribution algorithm based on interior point SSLE algorithm is proposed for solving inequality constrained optimization problems under the condition that the constraints are block-separable by the technology of sequential system of linear equation. Each iteration of this algorithm only needs to solve three systems of linear equations with the same coefficient matrix to obtain the descent direction. Furthermore, under certain conditions, the global convergence is achieved.

  15. Nutritional strategies to optimize dairy cattle immunity.

    Sordillo, L M

    2016-06-01

    Dairy cattle are susceptible to increased incidence and severity of both metabolic and infectious diseases during the periparturient period. A major contributing factor to increased health disorders is alterations in bovine immune mechanisms. Indeed, uncontrolled inflammation is a major contributing factor and a common link among several economically important infectious and metabolic diseases including mastitis, retained placenta, metritis, displaced abomasum, and ketosis. The nutritional status of dairy cows and the metabolism of specific nutrients are critical regulators of immune cell function. There is now a greater appreciation that certain mediators of the immune system can have a reciprocal effect on the metabolism of nutrients. Thus, any disturbances in nutritional or immunological homeostasis can provide deleterious feedback loops that can further enhance health disorders, increase production losses, and decrease the availability of safe and nutritious dairy foods for a growing global population. This review will discuss the complex interactions between nutrient metabolism and immune functions in periparturient dairy cattle. Details of how either deficiencies or overexposure to macro- and micronutrients can contribute to immune dysfunction and the subsequent development of health disorders will be presented. Specifically, the ways in which altered nutrient metabolism and oxidative stress can interact to compromise the immune system in transition cows will be discussed. A better understanding of the linkages between nutrition and immunity may facilitate the design of nutritional regimens that will reduce disease susceptibility in early lactation cows. Copyright © 2016 American Dairy Science Association. Published by Elsevier Inc. All rights reserved.

  16. A proposal of optimal sampling design using a modularity strategy

    Simone, A.; Giustolisi, O.; Laucelli, D. B.

    2016-08-01

    In real water distribution networks (WDNs) are present thousands nodes and optimal placement of pressure and flow observations is a relevant issue for different management tasks. The planning of pressure observations in terms of spatial distribution and number is named sampling design and it was faced considering model calibration. Nowadays, the design of system monitoring is a relevant issue for water utilities e.g., in order to manage background leakages, to detect anomalies and bursts, to guarantee service quality, etc. In recent years, the optimal location of flow observations related to design of optimal district metering areas (DMAs) and leakage management purposes has been faced considering optimal network segmentation and the modularity index using a multiobjective strategy. Optimal network segmentation is the basis to identify network modules by means of optimal conceptual cuts, which are the candidate locations of closed gates or flow meters creating the DMAs. Starting from the WDN-oriented modularity index, as a metric for WDN segmentation, this paper proposes a new way to perform the sampling design, i.e., the optimal location of pressure meters, using newly developed sampling-oriented modularity index. The strategy optimizes the pressure monitoring system mainly based on network topology and weights assigned to pipes according to the specific technical tasks. A multiobjective optimization minimizes the cost of pressure meters while maximizing the sampling-oriented modularity index. The methodology is presented and discussed using the Apulian and Exnet networks.

  17. Optimal reactor strategy for commercializing fast breeder reactors

    Yamaji, Kenji; Nagano, Koji

    1988-01-01

    In this paper, a fuel cycle optimization model developed for analyzing the condition of selecting fast breeder reactors in the optimal reactor strategy is described. By dividing the period of planning, 1966-2055, into nine ten-year periods, the model was formulated as a compact linear programming model. With the model, the best mix of reactor types as well as the optimal timing of reprocessing spent fuel from LWRs to minimize the total cost were found. The results of the analysis are summarized as follows. Fast breeder reactors could be introduced in the optimal strategy when they can economically compete with LWRs with 30 year storage of spent fuel. In order that fast breeder reactors monopolize the new reactor market after the achievement of their technical availability, their capital cost should be less than 0.9 times as much as that of LWRs. When a certain amount of reprocessing commitment is assumed, the condition of employing fast breeder reactors in the optimal strategy is mitigated. In the optimal strategy, reprocessing is done just to meet plutonium demand, and the storage of spent fuel is selected to adjust the mismatch of plutonium production and utilization. The price hike of uranium ore facilitates the commercial adoption of fast breeder reactors. (Kako, I.)

  18. Proposal of Evolutionary Simplex Method for Global Optimization Problem

    Shimizu, Yoshiaki

    To make an agile decision in a rational manner, role of optimization engineering has been notified increasingly under diversified customer demand. With this point of view, in this paper, we have proposed a new evolutionary method serving as an optimization technique in the paradigm of optimization engineering. The developed method has prospects to solve globally various complicated problem appearing in real world applications. It is evolved from the conventional method known as Nelder and Mead’s Simplex method by virtue of idea borrowed from recent meta-heuristic method such as PSO. Mentioning an algorithm to handle linear inequality constraints effectively, we have validated effectiveness of the proposed method through comparison with other methods using several benchmark problems.

  19. Global optimization for quantum dynamics of few-fermion systems

    Li, Xikun; Pecak, Daniel; Sowiński, Tomasz; Sherson, Jacob; Nielsen, Anne E. B.

    2018-03-01

    Quantum state preparation is vital to quantum computation and quantum information processing tasks. In adiabatic state preparation, the target state is theoretically obtained with nearly perfect fidelity if the control parameter is tuned slowly enough. As this, however, leads to slow dynamics, it is often desirable to be able to carry out processes more rapidly. In this work, we employ two global optimization methods to estimate the quantum speed limit for few-fermion systems confined in a one-dimensional harmonic trap. Such systems can be produced experimentally in a well-controlled manner. We determine the optimized control fields and achieve a reduction in the ramping time of more than a factor of four compared to linear ramping. We also investigate how robust the fidelity is to small variations of the control fields away from the optimized shapes.

  20. Optimal Portfolio Strategy under Rolling Economic Maximum Drawdown Constraints

    Xiaojian Yu

    2014-01-01

    Full Text Available This paper deals with the problem of optimal portfolio strategy under the constraints of rolling economic maximum drawdown. A more practical strategy is developed by using rolling Sharpe ratio in computing the allocation proportion in contrast to existing models. Besides, another novel strategy named “REDP strategy” is further proposed, which replaces the rolling economic drawdown of the portfolio with the rolling economic drawdown of the risky asset. The simulation tests prove that REDP strategy can ensure the portfolio to satisfy the drawdown constraint and outperforms other strategies significantly. An empirical comparison research on the performances of different strategies is carried out by using the 23-year monthly data of SPTR, DJUBS, and 3-month T-bill. The investment cases of single risky asset and two risky assets are both studied in this paper. Empirical results indicate that the REDP strategy successfully controls the maximum drawdown within the given limit and performs best in both return and risk.

  1. Multilevel Optimization Framework for Hierarchical Stiffened Shells Accelerated by Adaptive Equivalent Strategy

    Wang, Bo; Tian, Kuo; Zhao, Haixin; Hao, Peng; Zhu, Tianyu; Zhang, Ke; Ma, Yunlong

    2017-06-01

    In order to improve the post-buckling optimization efficiency of hierarchical stiffened shells, a multilevel optimization framework accelerated by adaptive equivalent strategy is presented in this paper. Firstly, the Numerical-based Smeared Stiffener Method (NSSM) for hierarchical stiffened shells is derived by means of the numerical implementation of asymptotic homogenization (NIAH) method. Based on the NSSM, a reasonable adaptive equivalent strategy for hierarchical stiffened shells is developed from the concept of hierarchy reduction. Its core idea is to self-adaptively decide which hierarchy of the structure should be equivalent according to the critical buckling mode rapidly predicted by NSSM. Compared with the detailed model, the high prediction accuracy and efficiency of the proposed model is highlighted. On the basis of this adaptive equivalent model, a multilevel optimization framework is then established by decomposing the complex entire optimization process into major-stiffener-level and minor-stiffener-level sub-optimizations, during which Fixed Point Iteration (FPI) is employed to accelerate convergence. Finally, the illustrative examples of the multilevel framework is carried out to demonstrate its efficiency and effectiveness to search for the global optimum result by contrast with the single-level optimization method. Remarkably, the high efficiency and flexibility of the adaptive equivalent strategy is indicated by compared with the single equivalent strategy.

  2. A Particle Swarm Optimization Variant with an Inner Variable Learning Strategy

    Guohua Wu

    2014-01-01

    Full Text Available Although Particle Swarm Optimization (PSO has demonstrated competitive performance in solving global optimization problems, it exhibits some limitations when dealing with optimization problems with high dimensionality and complex landscape. In this paper, we integrate some problem-oriented knowledge into the design of a certain PSO variant. The resulting novel PSO algorithm with an inner variable learning strategy (PSO-IVL is particularly efficient for optimizing functions with symmetric variables. Symmetric variables of the optimized function have to satisfy a certain quantitative relation. Based on this knowledge, the inner variable learning (IVL strategy helps the particle to inspect the relation among its inner variables, determine the exemplar variable for all other variables, and then make each variable learn from the exemplar variable in terms of their quantitative relations. In addition, we design a new trap detection and jumping out strategy to help particles escape from local optima. The trap detection operation is employed at the level of individual particles whereas the trap jumping out strategy is adaptive in its nature. Experimental simulations completed for some representative optimization functions demonstrate the excellent performance of PSO-IVL. The effectiveness of the PSO-IVL stresses a usefulness of augmenting evolutionary algorithms by problem-oriented domain knowledge.

  3. Optimal generator bidding strategies for power and ancillary services

    Morinec, Allen G.

    As the electric power industry transitions to a deregulated market, power transactions are made upon price rather than cost. Generator companies are interested in maximizing their profits rather than overall system efficiency. A method to equitably compensate generation providers for real power, and ancillary services such as reactive power and spinning reserve, will ensure a competitive market with an adequate number of suppliers. Optimizing the generation product mix during bidding is necessary to maximize a generator company's profits. The objective of this research work is to determine and formulate appropriate optimal bidding strategies for a generation company in both the energy and ancillary services markets. These strategies should incorporate the capability curves of their generators as constraints to define the optimal product mix and price offered in the day-ahead and real time spot markets. In order to achieve such a goal, a two-player model was composed to simulate market auctions for power generation. A dynamic game methodology was developed to identify Nash Equilibria and Mixed-Strategy Nash Equilibria solutions as optimal generation bidding strategies for two-player non-cooperative variable-sum matrix games with incomplete information. These games integrated the generation product mix of real power, reactive power, and spinning reserve with the generators's capability curves as constraints. The research includes simulations of market auctions, where strategies were tested for generators with different unit constraints, costs, types of competitors, strategies, and demand levels. Studies on the capability of large hydrogen cooled synchronous generators were utilized to derive useful equations that define the exact shape of the capability curve from the intersections of the arcs defined by the centers and radial vectors of the rotor, stator, and steady-state stability limits. The available reactive reserve and spinning reserve were calculated given a

  4. A Single-Degree-of-Freedom Energy Optimization Strategy for Power-Split Hybrid Electric Vehicles

    Chaoying Xia

    2017-07-01

    Full Text Available This paper presents a single-degree-of-freedom energy optimization strategy to solve the energy management problem existing in power-split hybrid electric vehicles (HEVs. The proposed strategy is based on a quadratic performance index, which is innovatively designed to simultaneously restrict the fluctuation of battery state of charge (SOC and reduce fuel consumption. An extended quadratic optimal control problem is formulated by approximating the fuel consumption rate as a quadratic polynomial of engine power. The approximated optimal control law is obtained by utilizing the solution properties of the Riccati equation and adjoint equation. It is easy to implement in real-time and the engineering significance is explained in details. In order to validate the effectiveness of the proposed strategy, the forward-facing vehicle simulation model is established based on the ADVISOR software (Version 2002, National Renewable Energy Laboratory, Golden, CO, USA. The simulation results show that there is only a little fuel consumption difference between the proposed strategy and the Pontryagin’s minimum principle (PMP-based global optimal strategy, and the proposed strategy also exhibits good adaptability under different initial battery SOC, cargo mass and road slope conditions.

  5. Application of optimal interation strategies to diffusion theory calculations

    Jones, R.B.

    1978-01-01

    The geometric interpretation of optimal (minimum computational time) iteration strategies is applied to one- and two-group, two-dimensional diffusion-theory calculations. The method is a ''spectral/time balance'' technique which weighs the convergence enhancement of the inner iteration procedure with that of the outer iteration loop and the time required to reconstruct the source. The diffusion-theory option of the discrete-ordinates transport code DOT3.5 was altered to incorporate the theoretical inner/outer decision logic. For the two-dimensional configuration considered, the optimal strategies reduced the total number of iterations performed for a given error criterion

  6. Global structural optimizations of surface systems with a genetic algorithm

    Chuang, Feng-Chuan

    2005-01-01

    Global structural optimizations with a genetic algorithm were performed for atomic cluster and surface systems including aluminum atomic clusters, Si magic clusters on the Si(111) 7 x 7 surface, silicon high-index surfaces, and Ag-induced Si(111) reconstructions. First, the global structural optimizations of neutral aluminum clusters Al n (n up to 23) were performed using a genetic algorithm coupled with a tight-binding potential. Second, a genetic algorithm in combination with tight-binding and first-principles calculations were performed to study the structures of magic clusters on the Si(111) 7 x 7 surface. Extensive calculations show that the magic cluster observed in scanning tunneling microscopy (STM) experiments consist of eight Si atoms. Simulated STM images of the Si magic cluster exhibit a ring-like feature similar to STM experiments. Third, a genetic algorithm coupled with a highly optimized empirical potential were used to determine the lowest energy structure of high-index semiconductor surfaces. The lowest energy structures of Si(105) and Si(114) were determined successfully. The results of Si(105) and Si(114) are reported within the framework of highly optimized empirical potential and first-principles calculations. Finally, a genetic algorithm coupled with Si and Ag tight-binding potentials were used to search for Ag-induced Si(111) reconstructions at various Ag and Si coverages. The optimized structural models of √3 x √3, 3 x 1, and 5 x 2 phases were reported using first-principles calculations. A novel model is found to have lower surface energy than the proposed double-honeycomb chained (DHC) model both for Au/Si(111) 5 x 2 and Ag/Si(111) 5 x 2 systems

  7. Globally convergent optimization algorithm using conservative convex separable diagonal quadratic approximations

    Groenwold, A.A.; Wood, D.W.; Etman, L.F.P.; Tosserams, S.

    2009-01-01

    We implement and test a globally convergent sequential approximate optimization algorithm based on (convexified) diagonal quadratic approximations. The algorithm resides in the class of globally convergent optimization methods based on conservative convex separable approximations developed by

  8. Optimization Under Uncertainty for Wake Steering Strategies: Preprint

    Quick, Julian [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Annoni, Jennifer [National Renewable Energy Laboratory (NREL), Golden, CO (United States); King, Ryan N [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Dykes, Katherine L [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Fleming, Paul A [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Ning, Andrew [Brigham Young University

    2017-05-01

    Wind turbines in a wind power plant experience significant power losses because of aerodynamic interactions between turbines. One control strategy to reduce these losses is known as 'wake steering,' in which upstream turbines are yawed to direct wakes away from downstream turbines. Previous wake steering research has assumed perfect information, however, there can be significant uncertainty in many aspects of the problem, including wind inflow and various turbine measurements. Uncertainty has significant implications for performance of wake steering strategies. Consequently, the authors formulate and solve an optimization under uncertainty (OUU) problem for finding optimal wake steering strategies in the presence of yaw angle uncertainty. The OUU wake steering strategy is demonstrated on a two-turbine test case and on the utility-scale, offshore Princess Amalia Wind Farm. When we accounted for yaw angle uncertainty in the Princess Amalia Wind Farm case, inflow-direction-specific OUU solutions produced between 0% and 1.4% more power than the deterministically optimized steering strategies, resulting in an overall annual average improvement of 0.2%. More importantly, the deterministic optimization is expected to perform worse and with more downside risk than the OUU result when realistic uncertainty is taken into account. Additionally, the OUU solution produces fewer extreme yaw situations than the deterministic solution.

  9. A Novel Hybrid Firefly Algorithm for Global Optimization.

    Lina Zhang

    Full Text Available Global optimization is challenging to solve due to its nonlinearity and multimodality. Traditional algorithms such as the gradient-based methods often struggle to deal with such problems and one of the current trends is to use metaheuristic algorithms. In this paper, a novel hybrid population-based global optimization algorithm, called hybrid firefly algorithm (HFA, is proposed by combining the advantages of both the firefly algorithm (FA and differential evolution (DE. FA and DE are executed in parallel to promote information sharing among the population and thus enhance searching efficiency. In order to evaluate the performance and efficiency of the proposed algorithm, a diverse set of selected benchmark functions are employed and these functions fall into two groups: unimodal and multimodal. The experimental results show better performance of the proposed algorithm compared to the original version of the firefly algorithm (FA, differential evolution (DE and particle swarm optimization (PSO in the sense of avoiding local minima and increasing the convergence rate.

  10. Optimal football strategies: AC Milan versus FC Barcelona

    Papahristodoulou, Christos

    2012-01-01

    In a recent UEFA Champions League game between AC Milan and FC Barcelona, played in Italy (final score 2-3), the collected match statistics, classified into four offensive and two defensive strategies, were in favour of FC Barcelona (by 13 versus 8 points). The aim of this paper is to examine to what extent the optimal game strategies derived from some deterministic, possibilistic, stochastic and fuzzy LP models would improve the payoff of AC Milan at the cost of FC Barcelona.

  11. Joint global optimization of tomographic data based on particle swarm optimization and decision theory

    Paasche, H.; Tronicke, J.

    2012-04-01

    In many near surface geophysical applications multiple tomographic data sets are routinely acquired to explore subsurface structures and parameters. Linking the model generation process of multi-method geophysical data sets can significantly reduce ambiguities in geophysical data analysis and model interpretation. Most geophysical inversion approaches rely on local search optimization methods used to find an optimal model in the vicinity of a user-given starting model. The final solution may critically depend on the initial model. Alternatively, global optimization (GO) methods have been used to invert geophysical data. They explore the solution space in more detail and determine the optimal model independently from the starting model. Additionally, they can be used to find sets of optimal models allowing a further analysis of model parameter uncertainties. Here we employ particle swarm optimization (PSO) to realize the global optimization of tomographic data. PSO is an emergent methods based on swarm intelligence characterized by fast and robust convergence towards optimal solutions. The fundamental principle of PSO is inspired by nature, since the algorithm mimics the behavior of a flock of birds searching food in a search space. In PSO, a number of particles cruise a multi-dimensional solution space striving to find optimal model solutions explaining the acquired data. The particles communicate their positions and success and direct their movement according to the position of the currently most successful particle of the swarm. The success of a particle, i.e. the quality of the currently found model by a particle, must be uniquely quantifiable to identify the swarm leader. When jointly inverting disparate data sets, the optimization solution has to satisfy multiple optimization objectives, at least one for each data set. Unique determination of the most successful particle currently leading the swarm is not possible. Instead, only statements about the Pareto

  12. International Pricing Strategies for Born-Global Firms

    Michael Neubert

    2017-10-01

    Full Text Available This paper aims to understand how born global firms develop their international pricing strategies, practices, and models. It aims to expand the study of international entrepreneurship and born global firms by including a broader and deeper range of pricing aspects than is normally found in the international entrepreneurship and pricing literature. The paper opted for a multiple case-study research design using different sources of evidence, including four in-depth interviews with CEOs of born global firms. The case-study firms were selected using a purposive selection method. The theoretical framework of Ingenbleek, Frambach & Verhallen is used. The results suggest that successful leaders act as ‘integrating forces’ on two levels: by applying a structured and disciplined price-setting process with regular reviews and by mediating between corporate financial goals and the local market reality. The results support the claim that policy makers should offer insights, training and financial support to give promising born global firms the possibility to select the most efficient international pricing models and strategies. The results are relevant for entrepreneurs to understand the importance of efficient price-modelling processes and the influence of the different price strategies and price models on financial results and sales revenues.

  13. The regions and global warming: Impacts and response strategies

    1991-01-01

    To date, much of the attention given to global warming in scientific research as well as in policy development has focused on the global picture. International negotiations and agreements to stabilize, and eventually reduce, greenhouse gas emissions are very important. By themselves, however, they are not sufficient to address global warming. Regional strategies are also needed. They can help reduce greenhouse gas emissions, and they will be the most effective way to mitigate the consequences of global warming. Adaptive strategies must respond to local and regional conditions. In many countries, subnational jurisdictions such as states and provinces or community organizations can already take effective actions without direction from their national government or waiting for international agreements. An important factor in defining regional approaches is the disparate consequences of climate change for developed and developing areas. Different strategies will also be needed for industrial and agricultural regions. Wealthy industrial regions may be better able to develop capital-intensive, adaptive infrastructure than regions with fewer discretionary resources where people are more vulnerable to the vagaries of weather patterns. On the other hand, regions that rely on indigenous knowledge and local resources may be better equipped to make incremental adaptations and more willing to modify life-styles. Ultimately, all climate change effects are experienced in specific places and effective response depends upon local action. We recognize that individual localities cannot solve a problem of global proportions by acting alone. However, a regional strategy can supplement international and national action and be the focal point for addressing risks in the unique social and economic context of a particular area. These meetings discussions dealt with the impacts and implications of climate change on such things as agriculture, forestry, and policy

  14. Design of Underwater Robot Lines Based on a Hybrid Automatic Optimization Strategy

    Wenjing Lyu; Weilin Luo

    2014-01-01

    In this paper, a hybrid automatic optimization strategy is proposed for the design of underwater robot lines. Isight is introduced as an integration platform. The construction of this platform is based on the user programming and several commercial software including UG6.0, GAMBIT2.4.6 and FLUENT12.0. An intelligent parameter optimization method, the particle swarm optimization, is incorporated into the platform. To verify the strategy proposed, a simulation is conducted on the underwater robot model 5470, which originates from the DTRC SUBOFF project. With the automatic optimization platform, the minimal resistance is taken as the optimization goal;the wet surface area as the constraint condition; the length of the fore-body, maximum body radius and after-body’s minimum radius as the design variables. With the CFD calculation, the RANS equations and the standard turbulence model are used for direct numerical simulation. By analyses of the simulation results, it is concluded that the platform is of high efficiency and feasibility. Through the platform, a variety of schemes for the design of the lines are generated and the optimal solution is achieved. The combination of the intelligent optimization algorithm and the numerical simulation ensures a global optimal solution and improves the efficiency of the searching solutions.

  15. Global low-carbon transition and China's response strategies

    Jian-Kun He

    2016-12-01

    Full Text Available The Paris Agreement establishes a new mechanism for post-2020 global climate governance, and sets long-term goals for global response to climate change, which will accelerate worldwide low-carbon transformation of economic development pattern, promote the revolutionary reform of energy system, boost a fundamental change in the mode of social production and consumption, and further the civilization of human society from industrial civilization to eco-civilization. The urgency of global low-carbon transition will reshape the competition situation of world's economy, trade and technology. Taking the construction of eco-civilization as a guide, China explores green and low-carbon development paths, establishes ambitious intended nationally determined contribution (INDC targets and action plans, advances energy production and consumption revolution, and speeds up the transformation of economic development pattern. These strategies and actions not only confirm to the trend of the world low-carbon transition, but also meet the intrinsic requirements for easing the domestic resources and environment constraints and realizing sustainable development. They are multi-win-win strategies for promotion of economic development and environmental protection and mitigation of carbon emissions. China should take the global long-term emission reduction targets as a guide, and formulate medium and long-term low-carbon development strategy, build the core competitiveness of low-carbon advanced technology and development pattern, and take an in-depth part in global governance so as to reflect the responsibility of China as a great power in constructing a community of common destiny for all mankind and addressing global ecological crisis.

  16. Optimal decentralized valley-filling charging strategy for electric vehicles

    Zhang, Kangkang; Xu, Liangfei; Ouyang, Minggao; Wang, Hewu; Lu, Languang; Li, Jianqiu; Li, Zhe

    2014-01-01

    Highlights: • An implementable charging strategy is developed for electric vehicles connected to a grid. • A two-dimensional pricing scheme is proposed to coordinate charging behaviors. • The strategy effectively works in decentralized way but achieves the systematic valley filling. • The strategy allows device-level charging autonomy, and does not require a bidirectional communication/control network. • The strategy can self-correct when confronted with adverse factors. - Abstract: Uncoordinated charging load of electric vehicles (EVs) increases the peak load of the power grid, thereby increasing the cost of electricity generation. The valley-filling charging scenario offers a cheaper alternative. This study proposes a novel decentralized valley-filling charging strategy, in which a day-ahead pricing scheme is designed by solving a minimum-cost optimization problem. The pricing scheme can be broadcasted to EV owners, and the individual charging behaviors can be indirectly coordinated. EV owners respond to the pricing scheme by autonomously optimizing their individual charge patterns. This device-level response induces a valley-filling effect in the grid at the system level. The proposed strategy offers three advantages: coordination (by the valley-filling effect), practicality (no requirement for a bidirectional communication/control network between the grid and EV owners), and autonomy (user control of EV charge patterns). The proposed strategy is validated in simulations of typical scenarios in Beijing, China. According to the results, the strategy (1) effectively achieves the valley-filling charging effect at 28% less generation cost than the uncoordinated charging strategy, (2) is robust to several potential affecters of the valley-filling effect, such as (system-level) inaccurate parameter estimation and (device-level) response capability and willingness (which cause less than 2% deviation in the minimal generation cost), and (3) is compatible with

  17. CHANGE MANAGEMENT STRATEGIES RELATED TO THE GLOBAL ENVIRONMENT COMPLEXITY

    Elena DOVAL

    2016-12-01

    Full Text Available The changes in organizations appear as a reaction to the organizational environment changes. In order to manage these changes successfully, the managers need to anticipate and design alternative strategies by preparing different options.  Nevertheless, the complexity of the global environment forces the managers to adopt strategies for their organizations that are facilitating the creation of new strategic competences and competitive advantages to face the environmental rapid changes. In this context, this paper is aiming to illustrate the main directions the change management may consider to change the organization strategies in order to harmonize them to the external environment, such as: integration versus externalization, flexible specialization and flexible organization, standardization versus adaptation, market segmentation, relationship building and maintaining and communication integration.  However, the new strategies are based on a changed attitude of the managers towards the competitive advantage that is dynamic and focused on creation rather then to operations.

  18. Global optimization of minority game by intelligent agents

    Xie, Yan-Bo; Wang, Bing-Hong; Hu, Chin-Kun; Zhou, Tao

    2005-10-01

    We propose a new model of minority game with intelligent agents who use trail and error method to make a choice such that the standard deviation σ2 and the total loss in this model reach the theoretical minimum values in the long time limit and the global optimization of the system is reached. This suggests that the economic systems can self-organize into a highly optimized state by agents who make decisions based on inductive thinking, limited knowledge, and capabilities. When other kinds of agents are also present, the simulation results and analytic calculations show that the intelligent agent can gain profits from producers and are much more competent than the noise traders and conventional agents in original minority games proposed by Challet and Zhang.

  19. Global optimization in the adaptive assay of subterranean uranium nodules

    Vulkan, U.; Ben-Haim, Y.

    1989-01-01

    An adaptive assay is one in which the design of the assay system is modified during operation in response to measurements obtained on-line. The present work has two aims: to design an adaptive system for borehole assay of isolated subterranean uranium nodules, and to investigate globality of optimal design in adaptive assay. It is shown experimentally that reasonably accurate estimates of uranium mass are obtained for a wide range of nodule shapes, on the basis of an adaptive assay system based on a simple geomorphological model. Furthermore, two concepts are identified which underlie the optimal design of the assay system. The adaptive assay approach shows promise for successful measurement of spatially random material in many geophysical applications. (author)

  20. A concept for global optimization of topology design problems

    Stolpe, Mathias; Achtziger, Wolfgang; Kawamoto, Atsushi

    2006-01-01

    We present a concept for solving topology design problems to proven global optimality. We propose that the problems are modeled using the approach of simultaneous analysis and design with discrete design variables and solved with convergent branch and bound type methods. This concept is illustrated...... on two applications. The first application is the design of stiff truss structures where the bar areas are chosen from a finite set of available areas. The second considered application is simultaneous topology and geometry design of planar articulated mechanisms. For each application we outline...

  1. A Competitive and Experiential Assignment in Search Engine Optimization Strategy

    Clarke, Theresa B.; Clarke, Irvine, III

    2014-01-01

    Despite an increase in ad spending and demand for employees with expertise in search engine optimization (SEO), methods for teaching this important marketing strategy have received little coverage in the literature. Using Bloom's cognitive goals hierarchy as a framework, this experiential assignment provides a process for educators who may be new…

  2. Optimal portfolio strategies under a shortfall constraint | Akume ...

    We impose dynamically, a shortfall constraint in terms of Tail Conditional Expectation on the portfolio selection problem in continuous time, in order to obtain optimal strategies. The nancial market is assumed to comprise n risky assets driven by geometric Brownian motion and one risk-free asset. The method of Lagrange ...

  3. Optimal energy management strategy for battery powered electric vehicles

    Xi, Jiaqi; Li, Mian; Xu, Min

    2014-01-01

    Highlights: • The power usage for battery-powered electrical vehicles with in-wheel motors is maximized. • The battery and motor dynamics are examined emphasized on the power conversion and utilization. • The optimal control strategy is derived and verified by simulations. • An analytic expression of the optimal operating point is obtained. - Abstract: Due to limited energy density of batteries, energy management has always played a critical role in improving the overall energy efficiency of electric vehicles. In this paper, a key issue within the energy management problem will be carefully tackled, i.e., maximizing the power usage of batteries for battery-powered electrical vehicles with in-wheel motors. To this end, the battery and motor dynamics will be thoroughly examined with particular emphasis on the power conversion and power utilization. The optimal control strategy will then be derived based on the analysis. One significant contribution of this work is that an analytic expression for the optimal operating point in terms of the component and environment parameters can be obtained. Owing to this finding, the derived control strategy is also rendered a simple structure for real-time implementation. Simulation results demonstrate that the proposed strategy works both adaptively and robustly under different driving scenarios

  4. Validation of optimization strategies using the linear structured production chains

    Kusiak, Jan; Morkisz, Paweł; Oprocha, Piotr; Pietrucha, Wojciech; Sztangret, Łukasz

    2017-06-01

    Different optimization strategies applied to sequence of several stages of production chains were validated in this paper. Two benchmark problems described by ordinary differential equations (ODEs) were considered. A water tank and a passive CR-RC filter were used as the exemplary objects described by the first and the second order differential equations, respectively. Considered in the work optimization problems serve as the validators of strategies elaborated by the Authors. However, the main goal of research is selection of the best strategy for optimization of two real metallurgical processes which will be investigated in an on-going projects. The first problem will be the oxidizing roasting process of zinc sulphide concentrate where the sulphur from the input concentrate should be eliminated and the minimal concentration of sulphide sulphur in the roasted products has to be achieved. Second problem will be the lead refining process consisting of three stages: roasting to the oxide, oxide reduction to metal and the oxidizing refining. Strategies, which appear the most effective in considered benchmark problems will be candidates for optimization of the mentioned above industrial processes.

  5. Global Search Strategies for Solving Multilinear Least-Squares Problems

    Mats Andersson

    2012-04-01

    Full Text Available The multilinear least-squares (MLLS problem is an extension of the linear least-squares problem. The difference is that a multilinear operator is used in place of a matrix-vector product. The MLLS is typically a large-scale problem characterized by a large number of local minimizers. It originates, for instance, from the design of filter networks. We present a global search strategy that allows for moving from one local minimizer to a better one. The efficiency of this strategy is illustrated by the results of numerical experiments performed for some problems related to the design of filter networks.

  6. An optimal inspection strategy for randomly failing equipment

    Chelbi, Anis; Ait-Kadi, Daoud

    1999-01-01

    This paper addresses the problem of generating optimal inspection strategies for randomly failing equipment where imminent failure is not obvious and can only be detected through inspection. Inspections are carried out following a condition-based procedure. The equipment is replaced if it has failed or if it shows imminent signs of failure. The latter state is indicated by measuring certain predetermined control parameters during inspection. Costs are associated with inspection, idle time and preventive or corrective actions. An optimal inspection strategy is defined as the inspection sequence minimizing the expected total cost per time unit over an infinite span. A mathematical model and a numerical algorithm are developed to generate an optimal inspection sequence. As a practical example, the model is applied to provide a machine tool operator with a time sequence for inspecting the cutting tool. The tool life time distribution and the trend of one control parameter defining its actual condition are supposed to be known

  7. Optimal Energy Control Strategy Design for a Hybrid Electric Vehicle

    Yuan Zou

    2013-01-01

    Full Text Available A heavy-duty parallel hybrid electric truck is modeled, and its optimal energy control is studied in this paper. The fundamental architecture of the parallel hybrid electric truck is modeled feed-forwardly, together with necessary dynamic features of subsystem or components. Dynamic programming (DP technique is adopted to find the optimal control strategy including the gear-shifting sequence and the power split between the engine and the motor subject to a battery SOC-sustaining constraint. Improved control rules are extracted from the DP-based control solution, forming near-optimal control strategies. Simulation results demonstrate that a significant improvement on the fuel economy can be achieved in the heavy-duty vehicle cycle from the natural driving statistics.

  8. Growth or reproduction: emergence of an evolutionary optimal strategy

    Grilli, J; Suweis, S; Maritan, A

    2013-01-01

    Modern ecology has re-emphasized the need for a quantitative understanding of the original ‘survival of the fittest theme’ based on analysis of the intricate trade-offs between competing evolutionary strategies that characterize the evolution of life. This is key to the understanding of species coexistence and ecosystem diversity under the omnipresent constraint of limited resources. In this work we propose an agent-based model replicating a community of interacting individuals, e.g. plants in a forest, where all are competing for the same finite amount of resources and each competitor is characterized by a specific growth–reproduction strategy. We show that such an evolution dynamics drives the system towards a stationary state characterized by an emergent optimal strategy, which in turn depends on the amount of available resources the ecosystem can rely on. We find that the share of resources used by individuals is power-law distributed with an exponent directly related to the optimal strategy. The model can be further generalized to devise optimal strategies in social and economical interacting systems dynamics. (paper)

  9. Efficient algorithms for multidimensional global optimization in genetic mapping of complex traits

    Kajsa Ljungberg

    2010-10-01

    Full Text Available Kajsa Ljungberg1, Kateryna Mishchenko2, Sverker Holmgren11Division of Scientific Computing, Department of Information Technology, Uppsala University, Uppsala, Sweden; 2Department of Mathematics and Physics, Mälardalen University College, Västerås, SwedenAbstract: We present a two-phase strategy for optimizing a multidimensional, nonconvex function arising during genetic mapping of quantitative traits. Such traits are believed to be affected by multiple so called QTL, and searching for d QTL results in a d-dimensional optimization problem with a large number of local optima. We combine the global algorithm DIRECT with a number of local optimization methods that accelerate the final convergence, and adapt the algorithms to problem-specific features. We also improve the evaluation of the QTL mapping objective function to enable exploitation of the smoothness properties of the optimization landscape. Our best two-phase method is demonstrated to be accurate in at least six dimensions and up to ten times faster than currently used QTL mapping algorithms.Keywords: global optimization, QTL mapping, DIRECT 

  10. Online gaming for learning optimal team strategies in real time

    Hudas, Gregory; Lewis, F. L.; Vamvoudakis, K. G.

    2010-04-01

    This paper first presents an overall view for dynamical decision-making in teams, both cooperative and competitive. Strategies for team decision problems, including optimal control, zero-sum 2-player games (H-infinity control) and so on are normally solved for off-line by solving associated matrix equations such as the Riccati equation. However, using that approach, players cannot change their objectives online in real time without calling for a completely new off-line solution for the new strategies. Therefore, in this paper we give a method for learning optimal team strategies online in real time as team dynamical play unfolds. In the linear quadratic regulator case, for instance, the method learns the Riccati equation solution online without ever solving the Riccati equation. This allows for truly dynamical team decisions where objective functions can change in real time and the system dynamics can be time-varying.

  11. Artificial root foraging optimizer algorithm with hybrid strategies

    Yang Liu

    2017-02-01

    Full Text Available In this work, a new plant-inspired optimization algorithm namely the hybrid artificial root foraging optimizion (HARFO is proposed, which mimics the iterative root foraging behaviors for complex optimization. In HARFO model, two innovative strategies were developed: one is the root-to-root communication strategy, which enables the individual exchange information with each other in different efficient topologies that can essentially improve the exploration ability; the other is co-evolution strategy, which can structure the hierarchical spatial population driven by evolutionary pressure of multiple sub-populations that ensure the diversity of root population to be well maintained. The proposed algorithm is benchmarked against four classical evolutionary algorithms on well-designed test function suites including both classical and composition test functions. Through the rigorous performance analysis that of all these tests highlight the significant performance improvement, and the comparative results show the superiority of the proposed algorithm.

  12. A Novel Consensus-Based Particle Swarm Optimization-Assisted Trust-Tech Methodology for Large-Scale Global Optimization.

    Zhang, Yong-Feng; Chiang, Hsiao-Dong

    2017-09-01

    A novel three-stage methodology, termed the "consensus-based particle swarm optimization (PSO)-assisted Trust-Tech methodology," to find global optimal solutions for nonlinear optimization problems is presented. It is composed of Trust-Tech methods, consensus-based PSO, and local optimization methods that are integrated to compute a set of high-quality local optimal solutions that can contain the global optimal solution. The proposed methodology compares very favorably with several recently developed PSO algorithms based on a set of small-dimension benchmark optimization problems and 20 large-dimension test functions from the CEC 2010 competition. The analytical basis for the proposed methodology is also provided. Experimental results demonstrate that the proposed methodology can rapidly obtain high-quality optimal solutions that can contain the global optimal solution. The scalability of the proposed methodology is promising.

  13. Identification of metabolic system parameters using global optimization methods

    Gatzke Edward P

    2006-01-01

    Full Text Available Abstract Background The problem of estimating the parameters of dynamic models of complex biological systems from time series data is becoming increasingly important. Methods and results Particular consideration is given to metabolic systems that are formulated as Generalized Mass Action (GMA models. The estimation problem is posed as a global optimization task, for which novel techniques can be applied to determine the best set of parameter values given the measured responses of the biological system. The challenge is that this task is nonconvex. Nonetheless, deterministic optimization techniques can be used to find a global solution that best reconciles the model parameters and measurements. Specifically, the paper employs branch-and-bound principles to identify the best set of model parameters from observed time course data and illustrates this method with an existing model of the fermentation pathway in Saccharomyces cerevisiae. This is a relatively simple yet representative system with five dependent states and a total of 19 unknown parameters of which the values are to be determined. Conclusion The efficacy of the branch-and-reduce algorithm is illustrated by the S. cerevisiae example. The method described in this paper is likely to be widely applicable in the dynamic modeling of metabolic networks.

  14. Burnout Syndrome: Global Medicine Volunteering as a Possible Treatment Strategy.

    Iserson, Kenneth V

    2018-04-01

    In the last few decades, "burnout syndrome" has become more common among clinicians, or at least more frequently recognized. Methods to prevent and treat burnout have had inconsistent results. Simultaneously, clinicians' interest in global medicine has increased dramatically, offering a possible intervention strategy for burnout while providing help to underserved areas. Caused by a variety of stressors, burnout syndrome ultimately results in physicians feeling that their work no longer embodies why they entered the medical field. This attitude harms clinicians, their patients and colleagues, and society. Few consistently successful interventions exist. At the same time, clinicians' interest in global medicine has risen exponentially. This paper reviews the basics of both phenomena and posits that global medicine experiences, although greatly assisting target populations, also may offer a strategy for combating burnout by reconnecting physicians with their love of the profession. Because studies have shown that regular volunteering improves mental health, short-term global medicine experiences may reinvigorate and reengage clinicians on the verge of, or suffering from, persistent burnout syndrome. Fortuitously, this intervention often will greatly benefit medically underserved populations. Copyright © 2018 Elsevier Inc. All rights reserved.

  15. Hybrid collaborative optimization based on selection strategy of initial point and adaptive relaxation

    Ji, Aimin; Yin, Xu; Yuan, Minghai [Hohai University, Changzhou (China)

    2015-09-15

    There are two problems in Collaborative optimization (CO): (1) the local optima arising from the selection of an inappropriate initial point; (2) the low efficiency and accuracy root in inappropriate relaxation factors. To solve these problems, we first develop the Latin hypercube design (LHD) to determine an initial point of optimization, and then use the non-linear programming by quadratic Lagrangian (NLPQL) to search for the global solution. The effectiveness of the initial point selection strategy is verified by three benchmark functions with some dimensions and different complexities. Then we propose the Adaptive relaxation collaborative optimization (ARCO) algorithm to solve the inconsistency between the system level and the disciplines level, and in this method, the relaxation factors are determined according to the three separated stages of CO respectively. The performance of the ARCO algorithm is compared with the standard collaborative algorithm and the constant relaxation collaborative algorithm with a typical numerical example, which indicates that the ARCO algorithm is more efficient and accurate. Finally, we propose a Hybrid collaborative optimization (HCO) approach, which integrates the selection strategy of initial point with the ARCO algorithm. The results show that HCO can achieve the global optimal solution without the initial value and it also has advantages in convergence, accuracy and robustness. Therefore, the proposed HCO approach can solve the CO problems with applications in the spindle and the speed reducer.

  16. Hybrid collaborative optimization based on selection strategy of initial point and adaptive relaxation

    Ji, Aimin; Yin, Xu; Yuan, Minghai

    2015-01-01

    There are two problems in Collaborative optimization (CO): (1) the local optima arising from the selection of an inappropriate initial point; (2) the low efficiency and accuracy root in inappropriate relaxation factors. To solve these problems, we first develop the Latin hypercube design (LHD) to determine an initial point of optimization, and then use the non-linear programming by quadratic Lagrangian (NLPQL) to search for the global solution. The effectiveness of the initial point selection strategy is verified by three benchmark functions with some dimensions and different complexities. Then we propose the Adaptive relaxation collaborative optimization (ARCO) algorithm to solve the inconsistency between the system level and the disciplines level, and in this method, the relaxation factors are determined according to the three separated stages of CO respectively. The performance of the ARCO algorithm is compared with the standard collaborative algorithm and the constant relaxation collaborative algorithm with a typical numerical example, which indicates that the ARCO algorithm is more efficient and accurate. Finally, we propose a Hybrid collaborative optimization (HCO) approach, which integrates the selection strategy of initial point with the ARCO algorithm. The results show that HCO can achieve the global optimal solution without the initial value and it also has advantages in convergence, accuracy and robustness. Therefore, the proposed HCO approach can solve the CO problems with applications in the spindle and the speed reducer

  17. Managing differences: the central challenge of global strategy.

    Ghemawat, Pankaj

    2007-03-01

    The main goal of any international strategy should be to manage the large differences that arise at the borders of markets. Yet executives often fail to exploit market and production discrepancies, focusing instead on the tensions between standardization and localization. In this article, Pankaj Ghemawat presents a new framework that encompasses all three effective responses to the challenges of globalization. He calls it the AAA Triangle. The A's stand for the three distinct types of international strategy. Through adaptation, companies seek to boost revenues and market share by maximizing their local relevance. Through aggregation, they attempt to deliver economies of scale by creating regional, or sometimes global, operations. And through arbitrage, they exploit disparities between national or regional markets, often by locating different parts of the supply chain in different places--for instance, call centers in India, factories in China, and retail shops in Western Europe. Ghemawat draws on several examples that illustrate how organizations use and balance these strategies and describes the trade-offs they make as they do so. Because most enterprises should draw from all three A's to some extent, the framework can be used to develop a summary scorecard indicating how well the company is globalizing. However, given the tensions among the strategies, it's not enough simply to tick off the corresponding boxes. Strategic choice requires some degree of prioritization--and the framework can help with that as well. While it is possible to make progress on all three strategies, companies usually must focus on one or two when trying to build competitive advantage.

  18. Possible global strategies for stopping polio vaccination and how they could be harmonized.

    Cochi, S L; Sutter, R W; Aylward, R B

    2001-01-01

    One of the challenges of the polio eradication initiative over the next few years will be the formulation of an optimal strategy for stopping poliovirus vaccination after global certification of polio eradication has been accomplished. This strategy must maximize the benefits and minimize the risks. A number of strategies are currently under consideration, including: (i) synchronized global discontinuation of use of oral poliovirus vaccine (OPV); (ii) regional or subregional coordinated OPV discontinuation; and (iii) moving from trivalent to bivalent or monovalent OPV. Other options include moving from OPV to global use of IPV for an interim period before cessation of IPV use (to eliminate circulation of vaccine-derived poliovirus, if necessary) or development of new OPV strains that are not transmissible. Each of these strategies is associated with specific advantages (financial benefits for OPV discontinuation) and disadvantages (cost of switch to IPV) and inherent uncertainties (risk of continued poliovirus circulation in certain populations or prolonged virus replication in immunodeficient persons). An ambitious research agenda addresses the remaining questions and issues. Nevertheless, several generalities are already clear. Unprecedented collaboration between countries, regions, and indeed the entire world will be required to implement a global OPV discontinuation strategy Regulatory approval will be needed for an interim bivalent OPV or for monovalent OPV in many countries. Manufacturers will need sufficient lead time to produce sufficient quantities of IPV Finally, the financial implications for any of these strategies need to be considered. Whatever strategy is followed it will be necessary to stockpile supplies of a poliovirus-containing vaccine (most probably all three types of monovalent OPV), and to develop contingency plans to respond should an outbreak of polio occur after stopping vaccination.

  19. GMG: A Guaranteed, Efficient Global Optimization Algorithm for Remote Sensing.

    D' Helon, CD

    2004-08-18

    The monocular passive ranging (MPR) problem in remote sensing consists of identifying the precise range of an airborne target (missile, plane, etc.) from its observed radiance. This inverse problem may be set as a global optimization problem (GOP) whereby the difference between the observed and model predicted radiances is minimized over the possible ranges and atmospheric conditions. Using additional information about the error function between the predicted and observed radiances of the target, we developed GMG, a new algorithm to find the Global Minimum with a Guarantee. The new algorithm transforms the original continuous GOP into a discrete search problem, thereby guaranteeing to find the position of the global minimum in a reasonably short time. The algorithm is first applied to the golf course problem, which serves as a litmus test for its performance in the presence of both complete and degraded additional information. GMG is further assessed on a set of standard benchmark functions and then applied to various realizations of the MPR problem.

  20. On the robust optimization to the uncertain vaccination strategy problem

    Chaerani, D.; Anggriani, N.; Firdaniza

    2014-01-01

    In order to prevent an epidemic of infectious diseases, the vaccination coverage needs to be minimized and also the basic reproduction number needs to be maintained below 1. This means that as we get the vaccination coverage as minimum as possible, thus we need to prevent the epidemic to a small number of people who already get infected. In this paper, we discuss the case of vaccination strategy in term of minimizing vaccination coverage, when the basic reproduction number is assumed as an uncertain parameter that lies between 0 and 1. We refer to the linear optimization model for vaccination strategy that propose by Becker and Starrzak (see [2]). Assuming that there is parameter uncertainty involved, we can see Tanner et al (see [9]) who propose the optimal solution of the problem using stochastic programming. In this paper we discuss an alternative way of optimizing the uncertain vaccination strategy using Robust Optimization (see [3]). In this approach we assume that the parameter uncertainty lies within an ellipsoidal uncertainty set such that we can claim that the obtained result will be achieved in a polynomial time algorithm (as it is guaranteed by the RO methodology). The robust counterpart model is presented

  1. On the robust optimization to the uncertain vaccination strategy problem

    Chaerani, D., E-mail: d.chaerani@unpad.ac.id; Anggriani, N., E-mail: d.chaerani@unpad.ac.id; Firdaniza, E-mail: d.chaerani@unpad.ac.id [Department of Mathematics, Faculty of Mathematics and Natural Sciences, University of Padjadjaran Indonesia, Jalan Raya Bandung Sumedang KM 21 Jatinangor Sumedang 45363 (Indonesia)

    2014-02-21

    In order to prevent an epidemic of infectious diseases, the vaccination coverage needs to be minimized and also the basic reproduction number needs to be maintained below 1. This means that as we get the vaccination coverage as minimum as possible, thus we need to prevent the epidemic to a small number of people who already get infected. In this paper, we discuss the case of vaccination strategy in term of minimizing vaccination coverage, when the basic reproduction number is assumed as an uncertain parameter that lies between 0 and 1. We refer to the linear optimization model for vaccination strategy that propose by Becker and Starrzak (see [2]). Assuming that there is parameter uncertainty involved, we can see Tanner et al (see [9]) who propose the optimal solution of the problem using stochastic programming. In this paper we discuss an alternative way of optimizing the uncertain vaccination strategy using Robust Optimization (see [3]). In this approach we assume that the parameter uncertainty lies within an ellipsoidal uncertainty set such that we can claim that the obtained result will be achieved in a polynomial time algorithm (as it is guaranteed by the RO methodology). The robust counterpart model is presented.

  2. Spatiotemporal radiotherapy planning using a global optimization approach

    Adibi, Ali; Salari, Ehsan

    2018-02-01

    This paper aims at quantifying the extent of potential therapeutic gain, measured using biologically effective dose (BED), that can be achieved by altering the radiation dose distribution over treatment sessions in fractionated radiotherapy. To that end, a spatiotemporally integrated planning approach is developed, where the spatial and temporal dose modulations are optimized simultaneously. The concept of equivalent uniform BED (EUBED) is used to quantify and compare the clinical quality of spatiotemporally heterogeneous dose distributions in target and critical structures. This gives rise to a large-scale non-convex treatment-plan optimization problem, which is solved using global optimization techniques. The proposed spatiotemporal planning approach is tested on two stylized cancer cases resembling two different tumor sites and sensitivity analysis is performed for radio-biological and EUBED parameters. Numerical results validate that spatiotemporal plans are capable of delivering a larger BED to the target volume without increasing the BED in critical structures compared to conventional time-invariant plans. In particular, this additional gain is attributed to the irradiation of different regions of the target volume at different treatment sessions. Additionally, the trade-off between the potential therapeutic gain and the number of distinct dose distributions is quantified, which suggests a diminishing marginal gain as the number of dose distributions increases.

  3. Deterministic global optimization algorithm based on outer approximation for the parameter estimation of nonlinear dynamic biological systems.

    Miró, Anton; Pozo, Carlos; Guillén-Gosálbez, Gonzalo; Egea, Jose A; Jiménez, Laureano

    2012-05-10

    The estimation of parameter values for mathematical models of biological systems is an optimization problem that is particularly challenging due to the nonlinearities involved. One major difficulty is the existence of multiple minima in which standard optimization methods may fall during the search. Deterministic global optimization methods overcome this limitation, ensuring convergence to the global optimum within a desired tolerance. Global optimization techniques are usually classified into stochastic and deterministic. The former typically lead to lower CPU times but offer no guarantee of convergence to the global minimum in a finite number of iterations. In contrast, deterministic methods provide solutions of a given quality (i.e., optimality gap), but tend to lead to large computational burdens. This work presents a deterministic outer approximation-based algorithm for the global optimization of dynamic problems arising in the parameter estimation of models of biological systems. Our approach, which offers a theoretical guarantee of convergence to global minimum, is based on reformulating the set of ordinary differential equations into an equivalent set of algebraic equations through the use of orthogonal collocation methods, giving rise to a nonconvex nonlinear programming (NLP) problem. This nonconvex NLP is decomposed into two hierarchical levels: a master mixed-integer linear programming problem (MILP) that provides a rigorous lower bound on the optimal solution, and a reduced-space slave NLP that yields an upper bound. The algorithm iterates between these two levels until a termination criterion is satisfied. The capabilities of our approach were tested in two benchmark problems, in which the performance of our algorithm was compared with that of the commercial global optimization package BARON. The proposed strategy produced near optimal solutions (i.e., within a desired tolerance) in a fraction of the CPU time required by BARON.

  4. Generating optimized stochastic power management strategies for electric car components

    Fruth, Matthias [TraceTronic GmbH, Dresden (Germany); Bastian, Steve [Technische Univ. Dresden (Germany)

    2012-11-01

    With the increasing prevalence of electric vehicles, reducing the power consumption of car components becomes a necessity. For the example of a novel traffic-light assistance system, which makes speed recommendations based on the expected length of red-light phases, power-management strategies are used to control under which conditions radio communication, positioning systems and other components are switched to low-power (e.g. sleep) or high-power (e.g. idle/busy) states. We apply dynamic power management, an optimization technique well-known from other domains, in order to compute energy-optimal power-management strategies, sometimes resulting in these strategies being stochastic. On the example of the traffic-light assistant, we present a MATLAB/Simulink-implemented framework for the generation, simulation and formal analysis of optimized power-management strategies, which is based on this technique. We study capabilities and limitations of this approach and sketch further applications in the automotive domain. (orig.)

  5. Optimal correction and design parameter search by modern methods of rigorous global optimization

    Makino, K.; Berz, M.

    2011-01-01

    Frequently the design of schemes for correction of aberrations or the determination of possible operating ranges for beamlines and cells in synchrotrons exhibit multitudes of possibilities for their correction, usually appearing in disconnected regions of parameter space which cannot be directly qualified by analytical means. In such cases, frequently an abundance of optimization runs are carried out, each of which determines a local minimum depending on the specific chosen initial conditions. Practical solutions are then obtained through an often extended interplay of experienced manual adjustment of certain suitable parameters and local searches by varying other parameters. However, in a formal sense this problem can be viewed as a global optimization problem, i.e. the determination of all solutions within a certain range of parameters that lead to a specific optimum. For example, it may be of interest to find all possible settings of multiple quadrupoles that can achieve imaging; or to find ahead of time all possible settings that achieve a particular tune; or to find all possible manners to adjust nonlinear parameters to achieve correction of high order aberrations. These tasks can easily be phrased in terms of such an optimization problem; but while mathematically this formulation is often straightforward, it has been common belief that it is of limited practical value since the resulting optimization problem cannot usually be solved. However, recent significant advances in modern methods of rigorous global optimization make these methods feasible for optics design for the first time. The key ideas of the method lie in an interplay of rigorous local underestimators of the objective functions, and by using the underestimators to rigorously iteratively eliminate regions that lie above already known upper bounds of the minima, in what is commonly known as a branch-and-bound approach. Recent enhancements of the Differential Algebraic methods used in particle

  6. Truss topology optimization with discrete design variables — Guaranteed global optimality and benchmark examples

    Achtziger, Wolfgang; Stolpe, Mathias

    2007-01-01

    this problem is well-studied for continuous bar areas, we consider in this study the case of discrete areas. This problem is of major practical relevance if the truss must be built from pre-produced bars with given areas. As a special case, we consider the design problem for a single available bar area, i.......e., a 0/1 problem. In contrast to the heuristic methods considered in many other approaches, our goal is to compute guaranteed globally optimal structures. This is done by a branch-and-bound method for which convergence can be proven. In this branch-and-bound framework, lower bounds of the optimal......-integer problems. The main intention of this paper is to provide optimal solutions for single and multiple load benchmark examples, which can be used for testing and validating other methods or heuristics for the treatment of this discrete topology design problem....

  7. An optimization strategy for a biokinetic model of inhaled radionuclides

    Shyr, L.J.; Griffith, W.C.; Boecker, B.B.

    1991-01-01

    Models for material disposition and dosimetry involve predictions of the biokinetics of the material among compartments representing organs and tissues in the body. Because of a lack of human data for most toxicants, many of the basic data are derived by modeling the results obtained from studies using laboratory animals. Such a biomathematical model is usually developed by adjusting the model parameters to make the model predictions match the measured retention and excretion data visually. The fitting process can be very time-consuming for a complicated model, and visual model selections may be subjective and easily biased by the scale or the data used. Due to the development of computerized optimization methods, manual fitting could benefit from an automated process. However, for a complicated model, an automated process without an optimization strategy will not be efficient, and may not produce fruitful results. In this paper, procedures for, and implementation of, an optimization strategy for a complicated mathematical model is demonstrated by optimizing a biokinetic model for 144Ce in fused aluminosilicate particles inhaled by beagle dogs. The optimized results using SimuSolv were compared to manual fitting results obtained previously using the model simulation software GASP. Also, statistical criteria provided by SimuSolv, such as likelihood function values, were used to help or verify visual model selections

  8. Control strategies for wind farm power optimization: LES study

    Ciri, Umberto; Rotea, Mario; Leonardi, Stefano

    2017-11-01

    Turbines in wind farms operate in off-design conditions as wake interactions occur for particular wind directions. Advanced wind farm control strategies aim at coordinating and adjusting turbine operations to mitigate power losses in such conditions. Coordination is achieved by controlling on upstream turbines either the wake intensity, through the blade pitch angle or the generator torque, or the wake direction, through yaw misalignment. Downstream turbines can be adapted to work in waked conditions and limit power losses, using the blade pitch angle or the generator torque. As wind conditions in wind farm operations may change significantly, it is difficult to determine and parameterize the variations of the coordinated optimal settings. An alternative is model-free control and optimization of wind farms, which does not require any parameterization and can track the optimal settings as conditions vary. In this work, we employ a model-free optimization algorithm, extremum-seeking control, to find the optimal set-points of generator torque, blade pitch and yaw angle for a three-turbine configuration. Large-Eddy Simulations are used to provide a virtual environment to evaluate the performance of the control strategies under realistic, unsteady incoming wind. This work was supported by the National Science Foundation, Grants No. 1243482 (the WINDINSPIRE project) and IIP 1362033 (I/UCRC WindSTAR). TACC is acknowledged for providing computational time.

  9. Reaktualisasi Strategi Pendidikan Islam: Ikhtiar Mengimbangi Pendidikan Global

    M. Sobry

    2014-06-01

    Full Text Available Abstract: Globalization is inevitable phenomenon that may cause anxiety amongst countries, such as Indonesia, that still preserve their culture, ethics and religious values because it always introduces new things that are not easily adjusted to regional or local contexts. Globalization as it is reflected in rapid change and transformation in technology has affected most of human’s life, including education. Globalized education is the one that is characterized by global and transnational elements in its basic structure, for example, the use of information technologies and digital media that have both positive and negative impacts. However, for Indonesia, whose majority population is Islam, globalization is not a threat, which should be evaded. What needs to do is to integrate Islamic concepts and values in it. Globalization and its type of education that looks contrary to religious norms will no longer become a menace if it is strengthened with religious values.    Abstrak: Globalisasi merupakan fenomena kekinian yang terkadang dipandang sebagai momok dalam konteks bangsa, seperti Indonesia, yang berhasrat kuat melestarikan nilai adat, budaya, moral, dan nilai agama. Tulisan ini mencermati globalisasi yang memengaruhi dunia pendidikan sebagaimana terlihat pada semakin luasnya penggunaan media digital dengan semua manfaat dan mudarat yang menyertainya. Penulis berpendapat bahwa fenomena itu semestinya dipandang wajar dan dihadapi dengan lapang dada. Namun ia harus diimbangi dengan konsep-konsep islami dan diperkuat dengan strategi islami pula. Islam memiliki konsep moralitas dan etika yang komprehensif untuk diaktualisasikan dalam konteks arus globalisasi. Oleh karena itu, tidak ada jalan lain untuk mengimbangi pendidikan global saat ini kecuali dengan kembali kepangkuan konsep-konsep pendidikan Islam. 

  10. Automatic CT simulation optimization for radiation therapy: A general strategy.

    Li, Hua; Yu, Lifeng; Anastasio, Mark A; Chen, Hsin-Chen; Tan, Jun; Gay, Hiram; Michalski, Jeff M; Low, Daniel A; Mutic, Sasa

    2014-03-01

    In radiation therapy, x-ray computed tomography (CT) simulation protocol specifications should be driven by the treatment planning requirements in lieu of duplicating diagnostic CT screening protocols. The purpose of this study was to develop a general strategy that allows for automatically, prospectively, and objectively determining the optimal patient-specific CT simulation protocols based on radiation-therapy goals, namely, maintenance of contouring quality and integrity while minimizing patient CT simulation dose. The authors proposed a general prediction strategy that provides automatic optimal CT simulation protocol selection as a function of patient size and treatment planning task. The optimal protocol is the one that delivers the minimum dose required to provide a CT simulation scan that yields accurate contours. Accurate treatment plans depend on accurate contours in order to conform the dose to actual tumor and normal organ positions. An image quality index, defined to characterize how simulation scan quality affects contour delineation, was developed and used to benchmark the contouring accuracy and treatment plan quality within the predication strategy. A clinical workflow was developed to select the optimal CT simulation protocols incorporating patient size, target delineation, and radiation dose efficiency. An experimental study using an anthropomorphic pelvis phantom with added-bolus layers was used to demonstrate how the proposed prediction strategy could be implemented and how the optimal CT simulation protocols could be selected for prostate cancer patients based on patient size and treatment planning task. Clinical IMRT prostate treatment plans for seven CT scans with varied image quality indices were separately optimized and compared to verify the trace of target and organ dosimetry coverage. Based on the phantom study, the optimal image quality index for accurate manual prostate contouring was 4.4. The optimal tube potentials for patient sizes

  11. Automatic CT simulation optimization for radiation therapy: A general strategy

    Li, Hua, E-mail: huli@radonc.wustl.edu; Chen, Hsin-Chen; Tan, Jun; Gay, Hiram; Michalski, Jeff M.; Mutic, Sasa [Department of Radiation Oncology, Washington University, St. Louis, Missouri 63110 (United States); Yu, Lifeng [Department of Radiology, Mayo Clinic, Rochester, Minnesota 55905 (United States); Anastasio, Mark A. [Department of Biomedical Engineering, Washington University, St. Louis, Missouri 63110 (United States); Low, Daniel A. [Department of Radiation Oncology, University of California Los Angeles, Los Angeles, California 90095 (United States)

    2014-03-15

    Purpose: In radiation therapy, x-ray computed tomography (CT) simulation protocol specifications should be driven by the treatment planning requirements in lieu of duplicating diagnostic CT screening protocols. The purpose of this study was to develop a general strategy that allows for automatically, prospectively, and objectively determining the optimal patient-specific CT simulation protocols based on radiation-therapy goals, namely, maintenance of contouring quality and integrity while minimizing patient CT simulation dose. Methods: The authors proposed a general prediction strategy that provides automatic optimal CT simulation protocol selection as a function of patient size and treatment planning task. The optimal protocol is the one that delivers the minimum dose required to provide a CT simulation scan that yields accurate contours. Accurate treatment plans depend on accurate contours in order to conform the dose to actual tumor and normal organ positions. An image quality index, defined to characterize how simulation scan quality affects contour delineation, was developed and used to benchmark the contouring accuracy and treatment plan quality within the predication strategy. A clinical workflow was developed to select the optimal CT simulation protocols incorporating patient size, target delineation, and radiation dose efficiency. An experimental study using an anthropomorphic pelvis phantom with added-bolus layers was used to demonstrate how the proposed prediction strategy could be implemented and how the optimal CT simulation protocols could be selected for prostate cancer patients based on patient size and treatment planning task. Clinical IMRT prostate treatment plans for seven CT scans with varied image quality indices were separately optimized and compared to verify the trace of target and organ dosimetry coverage. Results: Based on the phantom study, the optimal image quality index for accurate manual prostate contouring was 4.4. The optimal tube

  12. Transitions in optimal adaptive strategies for populations in fluctuating environments

    Mayer, Andreas; Mora, Thierry; Rivoire, Olivier; Walczak, Aleksandra M.

    2017-09-01

    Biological populations are subject to fluctuating environmental conditions. Different adaptive strategies can allow them to cope with these fluctuations: specialization to one particular environmental condition, adoption of a generalist phenotype that compromises between conditions, or population-wise diversification (bet hedging). Which strategy provides the largest selective advantage in the long run depends on the range of accessible phenotypes and the statistics of the environmental fluctuations. Here, we analyze this problem in a simple mathematical model of population growth. First, we review and extend a graphical method to identify the nature of the optimal strategy when the environmental fluctuations are uncorrelated. Temporal correlations in environmental fluctuations open up new strategies that rely on memory but are mathematically challenging to study: We present analytical results to address this challenge. We illustrate our general approach by analyzing optimal adaptive strategies in the presence of trade-offs that constrain the range of accessible phenotypes. Our results extend several previous studies and have applications to a variety of biological phenomena, from antibiotic resistance in bacteria to immune responses in vertebrates.

  13. Research on optimal investment path of transmission corridor under the global energy Internet

    Huang, Yuehui; Li, Pai; Wang, Qi; Liu, Jichun; Gao, Han

    2018-02-01

    Under the background of the global energy Internet, the investment planning of transmission corridor from XinJiang to Germany is studied in this article, which passes through four countries: Kazakhstan, Russia, Belarus and Poland. Taking the specific situation of different countries into account, including the length of transmission line, unit construction cost, completion time, transmission price, state tariff, inflation rate and so on, this paper constructed a power transmission investment model. Finally, the dynamic programming method is used to simulate the example, and the optimal strategies under different objective functions are obtained.

  14. Eye Movements Reveal Optimal Strategies for Analogical Reasoning.

    Vendetti, Michael S; Starr, Ariel; Johnson, Elizabeth L; Modavi, Kiana; Bunge, Silvia A

    2017-01-01

    Analogical reasoning refers to the process of drawing inferences on the basis of the relational similarity between two domains. Although this complex cognitive ability has been the focus of inquiry for many years, most models rely on measures that cannot capture individuals' thought processes moment by moment. In the present study, we used participants' eye movements to investigate reasoning strategies in real time while solving visual propositional analogy problems (A:B::C:D). We included both a semantic and a perceptual lure on every trial to determine how these types of distracting information influence reasoning strategies. Participants spent more time fixating the analogy terms and the target relative to the other response choices, and made more saccades between the A and B items than between any other items. Participants' eyes were initially drawn to perceptual lures when looking at response choices, but they nonetheless performed the task accurately. We used participants' gaze sequences to classify each trial as representing one of three classic analogy problem solving strategies and related strategy usage to analogical reasoning performance. A project-first strategy, in which participants first extrapolate the relation between the AB pair and then generalize that relation for the C item, was both the most commonly used strategy as well as the optimal strategy for solving visual analogy problems. These findings provide new insight into the role of strategic processing in analogical problem solving.

  15. Eye Movements Reveal Optimal Strategies for Analogical Reasoning

    Michael S. Vendetti

    2017-06-01

    Full Text Available Analogical reasoning refers to the process of drawing inferences on the basis of the relational similarity between two domains. Although this complex cognitive ability has been the focus of inquiry for many years, most models rely on measures that cannot capture individuals' thought processes moment by moment. In the present study, we used participants' eye movements to investigate reasoning strategies in real time while solving visual propositional analogy problems (A:B::C:D. We included both a semantic and a perceptual lure on every trial to determine how these types of distracting information influence reasoning strategies. Participants spent more time fixating the analogy terms and the target relative to the other response choices, and made more saccades between the A and B items than between any other items. Participants' eyes were initially drawn to perceptual lures when looking at response choices, but they nonetheless performed the task accurately. We used participants' gaze sequences to classify each trial as representing one of three classic analogy problem solving strategies and related strategy usage to analogical reasoning performance. A project-first strategy, in which participants first extrapolate the relation between the AB pair and then generalize that relation for the C item, was both the most commonly used strategy as well as the optimal strategy for solving visual analogy problems. These findings provide new insight into the role of strategic processing in analogical problem solving.

  16. A review of Thailand's strategies for global climate change

    Boonchalermkit, S.

    1994-01-01

    Thailand is greatly concerned about global climate change, which is caused primarily by the burning of fossil fuels, deforestation and the release of chlorofluorocarbons. The country itself is not currently a major contributor to global climate change. However, as Thailand's economy expands and its burning of fossil fuels increases, the country's contribution to global climate change could increase. Thailand's use of primary energy supplies grew at an average rate of 13.4 percent per year in the period 1985 to 1990. The rapid, sustained growth was due to the overall pace of growth in the economy and the expansion of industrial, construction, and transportation activities. The primary energy demand was approximately 31,600 kilotons of oil equivalent (KTOE) in 1990. The transportation sector accounted for the largest proportion of energy demand at 30 percent. Within the next 15 years, the power sector is expected to overtake the transportation sector as the largest consumer of energy. Petroleum is currently the predominant source of energy in Thailand, accounting for 56 percent of the primary energy demand. Thailand recognizes that it has an important part to play in finding solutions to minimizing emissions of greenhouse gases and identifying viable response strategies. Thus, in this paper the authors will present several policy strategies relevant to climate change in Thailand and discuss how they have been implemented and enforced. Policies concerning forestry, energy, and environment are reviewed in detail in this paper

  17. Terrestrial ecosystem responses to global change: A research strategy

    NONE

    1998-09-01

    Uncertainty about the magnitude of global change effects on terrestrial ecosystems and consequent feedbacks to the atmosphere impedes sound policy planning at regional, national, and global scales. A strategy to reduce these uncertainties must include a substantial increase in funding for large-scale ecosystem experiments and a careful prioritization of research efforts. Prioritization criteria should be based on the magnitude of potential changes in environmental properties of concern to society, including productivity; biodiversity; the storage and cycling of carbon, water, and nutrients; and sensitivity of specific ecosystems to environmental change. A research strategy is proposed that builds on existing knowledge of ecosystem responses to global change by (1) expanding the spatial and temporal scale of experimental ecosystem manipulations to include processes known to occur at large scales and over long time periods; (2) quantifying poorly understood linkages among processes through the use of experiments that manipulate multiple interacting environmental factors over a broader range of relevant conditions than did past experiments; and (3) prioritizing ecosystems for major experimental manipulations on the basis of potential positive and negative impacts on ecosystem properties and processes of intrinsic and/or utilitarian value to humans and on feedbacks of terrestrial ecosystems to the atmosphere.

  18. In-operation learning of optimal wind farm operation strategy

    Oliva Gratacós, Joan

    2017-01-01

    In a wind farm, power losses due to wind turbine wake effects can be up to 30-40% under certain conditions. As the global installed wind power capacity increases, the mitigation of wake effects in wind farms is gaining more importance. Following a conventional control strategy, each individual turbine maximizes its own power production without taking into consideration its effects on the performance of downstream turbines. Therefore, this control scheme results in operation con...

  19. Optimal intervention strategies for cholera outbreak by education and chlorination

    Bakhtiar, Toni

    2016-01-01

    This paper discusses the control of infectious diseases in the framework of optimal control approach. A case study on cholera control was studied by considering two control strategies, namely education and chlorination. We distinct the former control into one regarding person-to-person behaviour and another one concerning person-to-environment conduct. Model are divided into two interacted populations: human population which follows an SIR model and pathogen population. Pontryagin maximum principle was applied in deriving a set of differential equations which consists of dynamical and adjoin systems as optimality conditions. Then, the fourth order Runge-Kutta method was exploited to numerically solve the equation system. An illustrative example was provided to assess the effectiveness of the control strategies toward a set of control scenarios.

  20. Modelling and Optimal Control of Typhoid Fever Disease with Cost-Effective Strategies.

    Tilahun, Getachew Teshome; Makinde, Oluwole Daniel; Malonza, David

    2017-01-01

    We propose and analyze a compartmental nonlinear deterministic mathematical model for the typhoid fever outbreak and optimal control strategies in a community with varying population. The model is studied qualitatively using stability theory of differential equations and the basic reproductive number that represents the epidemic indicator is obtained from the largest eigenvalue of the next-generation matrix. Both local and global asymptotic stability conditions for disease-free and endemic equilibria are determined. The model exhibits a forward transcritical bifurcation and the sensitivity analysis is performed. The optimal control problem is designed by applying Pontryagin maximum principle with three control strategies, namely, the prevention strategy through sanitation, proper hygiene, and vaccination; the treatment strategy through application of appropriate medicine; and the screening of the carriers. The cost functional accounts for the cost involved in prevention, screening, and treatment together with the total number of the infected persons averted. Numerical results for the typhoid outbreak dynamics and its optimal control revealed that a combination of prevention and treatment is the best cost-effective strategy to eradicate the disease.

  1. Optimization Strategies for Bruch's Membrane Opening Minimum Rim Area Calculation: Sequential versus Simultaneous Minimization.

    Enders, Philip; Adler, Werner; Schaub, Friederike; Hermann, Manuel M; Diestelhorst, Michael; Dietlein, Thomas; Cursiefen, Claus; Heindl, Ludwig M

    2017-10-24

    To compare a simultaneously optimized continuous minimum rim surface parameter between Bruch's membrane opening (BMO) and the internal limiting membrane to the standard sequential minimization used for calculating the BMO minimum rim area in spectral domain optical coherence tomography (SD-OCT). In this case-control, cross-sectional study, 704 eyes of 445 participants underwent SD-OCT of the optic nerve head (ONH), visual field testing, and clinical examination. Globally and clock-hour sector-wise optimized BMO-based minimum rim area was calculated independently. Outcome parameters included BMO-globally optimized minimum rim area (BMO-gMRA) and sector-wise optimized BMO-minimum rim area (BMO-MRA). BMO area was 1.89 ± 0.05 mm 2 . Mean global BMO-MRA was 0.97 ± 0.34 mm 2 , mean global BMO-gMRA was 1.01 ± 0.36 mm 2 . Both parameters correlated with r = 0.995 (P < 0.001); mean difference was 0.04 mm 2 (P < 0.001). In all sectors, parameters differed by 3.0-4.2%. In receiver operating characteristics, the calculated area under the curve (AUC) to differentiate glaucoma was 0.873 for BMO-MRA, compared to 0.866 for BMO-gMRA (P = 0.004). Among ONH sectors, the temporal inferior location showed the highest AUC. Optimization strategies to calculate BMO-based minimum rim area led to significantly different results. Imposing an additional adjacency constraint within calculation of BMO-MRA does not improve diagnostic power. Global and temporal inferior BMO-MRA performed best in differentiating glaucoma patients.

  2. Implementation and verification of global optimization benchmark problems

    Posypkin, Mikhail; Usov, Alexander

    2017-12-01

    The paper considers the implementation and verification of a test suite containing 150 benchmarks for global deterministic box-constrained optimization. A C++ library for describing standard mathematical expressions was developed for this purpose. The library automate the process of generating the value of a function and its' gradient at a given point and the interval estimates of a function and its' gradient on a given box using a single description. Based on this functionality, we have developed a collection of tests for an automatic verification of the proposed benchmarks. The verification has shown that literary sources contain mistakes in the benchmarks description. The library and the test suite are available for download and can be used freely.

  3. Implementation and verification of global optimization benchmark problems

    Posypkin Mikhail

    2017-12-01

    Full Text Available The paper considers the implementation and verification of a test suite containing 150 benchmarks for global deterministic box-constrained optimization. A C++ library for describing standard mathematical expressions was developed for this purpose. The library automate the process of generating the value of a function and its’ gradient at a given point and the interval estimates of a function and its’ gradient on a given box using a single description. Based on this functionality, we have developed a collection of tests for an automatic verification of the proposed benchmarks. The verification has shown that literary sources contain mistakes in the benchmarks description. The library and the test suite are available for download and can be used freely.

  4. Adjusting process count on demand for petascale global optimization

    Sosonkina, Masha; Watson, Layne T.; Radcliffe, Nicholas R.; Haftka, Rafael T.; Trosset, Michael W.

    2013-01-01

    There are many challenges that need to be met before efficient and reliable computation at the petascale is possible. Many scientific and engineering codes running at the petascale are likely to be memory intensive, which makes thrashing a serious problem for many petascale applications. One way to overcome this challenge is to use a dynamic number of processes, so that the total amount of memory available for the computation can be increased on demand. This paper describes modifications made to the massively parallel global optimization code pVTdirect in order to allow for a dynamic number of processes. In particular, the modified version of the code monitors memory use and spawns new processes if the amount of available memory is determined to be insufficient. The primary design challenges are discussed, and performance results are presented and analyzed.

  5. Ringed Seal Search for Global Optimization via a Sensitive Search Model.

    Younes Saadi

    Full Text Available The efficiency of a metaheuristic algorithm for global optimization is based on its ability to search and find the global optimum. However, a good search often requires to be balanced between exploration and exploitation of the search space. In this paper, a new metaheuristic algorithm called Ringed Seal Search (RSS is introduced. It is inspired by the natural behavior of the seal pup. This algorithm mimics the seal pup movement behavior and its ability to search and choose the best lair to escape predators. The scenario starts once the seal mother gives birth to a new pup in a birthing lair that is constructed for this purpose. The seal pup strategy consists of searching and selecting the best lair by performing a random walk to find a new lair. Affected by the sensitive nature of seals against external noise emitted by predators, the random walk of the seal pup takes two different search states, normal state and urgent state. In the normal state, the pup performs an intensive search between closely adjacent lairs; this movement is modeled via a Brownian walk. In an urgent state, the pup leaves the proximity area and performs an extensive search to find a new lair from sparse targets; this movement is modeled via a Levy walk. The switch between these two states is realized by the random noise emitted by predators. The algorithm keeps switching between normal and urgent states until the global optimum is reached. Tests and validations were performed using fifteen benchmark test functions to compare the performance of RSS with other baseline algorithms. The results show that RSS is more efficient than Genetic Algorithm, Particles Swarm Optimization and Cuckoo Search in terms of convergence rate to the global optimum. The RSS shows an improvement in terms of balance between exploration (extensive and exploitation (intensive of the search space. The RSS can efficiently mimic seal pups behavior to find best lair and provide a new algorithm to be

  6. Turbine Control Strategies for Wind Farm Power Optimization

    Mirzaei, Mahmood; Göçmen Bozkurt, Tuhfe; Giebel, Gregor

    2015-01-01

    In recent decades there has been increasing interest in green energies, of which wind energy is the most important one. In order to improve the competitiveness of the wind power plants, there are ongoing researches to decrease cost per energy unit and increase the efficiency of wind turbines...... and wind farms. One way of achieving these goals is to optimize the power generated by a wind farm. One optimization method is to choose appropriate operating points for the individual wind turbines in the farm. We have made three models of a wind farm based on three difference control strategies...... the generated power by changing the power reference of the individual wind turbines. We use the optimization setup to compare power production of the wind farm models. This paper shows that for the most frequent wind velocities (below and around the rated values), the generated powers of the wind farms...

  7. Integrated testing strategies can be optimal for chemical risk classification.

    Raseta, Marko; Pitchford, Jon; Cussens, James; Doe, John

    2017-08-01

    There is an urgent need to refine strategies for testing the safety of chemical compounds. This need arises both from the financial and ethical costs of animal tests, but also from the opportunities presented by new in-vitro and in-silico alternatives. Here we explore the mathematical theory underpinning the formulation of optimal testing strategies in toxicology. We show how the costs and imprecisions of the various tests, and the variability in exposures and responses of individuals, can be assembled rationally to form a Markov Decision Problem. We compute the corresponding optimal policies using well developed theory based on Dynamic Programming, thereby identifying and overcoming some methodological and logical inconsistencies which may exist in the current toxicological testing. By illustrating our methods for two simple but readily generalisable examples we show how so-called integrated testing strategies, where information of different precisions from different sources is combined and where different initial test outcomes lead to different sets of future tests, can arise naturally as optimal policies. Copyright © 2017 Elsevier Inc. All rights reserved.

  8. ABCluster: the artificial bee colony algorithm for cluster global optimization.

    Zhang, Jun; Dolg, Michael

    2015-10-07

    Global optimization of cluster geometries is of fundamental importance in chemistry and an interesting problem in applied mathematics. In this work, we introduce a relatively new swarm intelligence algorithm, i.e. the artificial bee colony (ABC) algorithm proposed in 2005, to this field. It is inspired by the foraging behavior of a bee colony, and only three parameters are needed to control it. We applied it to several potential functions of quite different nature, i.e., the Coulomb-Born-Mayer, Lennard-Jones, Morse, Z and Gupta potentials. The benchmarks reveal that for long-ranged potentials the ABC algorithm is very efficient in locating the global minimum, while for short-ranged ones it is sometimes trapped into a local minimum funnel on a potential energy surface of large clusters. We have released an efficient, user-friendly, and free program "ABCluster" to realize the ABC algorithm. It is a black-box program for non-experts as well as experts and might become a useful tool for chemists to study clusters.

  9. Globally-Optimized Local Pseudopotentials for (Orbital-Free) Density Functional Theory Simulations of Liquids and Solids.

    Del Rio, Beatriz G; Dieterich, Johannes M; Carter, Emily A

    2017-08-08

    The accuracy of local pseudopotentials (LPSs) is one of two major determinants of the fidelity of orbital-free density functional theory (OFDFT) simulations. We present a global optimization strategy for LPSs that enables OFDFT to reproduce solid and liquid properties obtained from Kohn-Sham DFT. Our optimization strategy can fit arbitrary properties from both solid and liquid phases, so the resulting globally optimized local pseudopotentials (goLPSs) can be used in solid and/or liquid-phase simulations depending on the fitting process. We show three test cases proving that we can (1) improve solid properties compared to our previous bulk-derived local pseudopotential generation scheme; (2) refine predicted liquid and solid properties by adding force matching data; and (3) generate a from-scratch, accurate goLPS from the local channel of a non-local pseudopotential. The proposed scheme therefore serves as a full and improved LPS construction protocol.

  10. VI International Workshop on Nature Inspired Cooperative Strategies for Optimization

    Otero, Fernando; Masegosa, Antonio

    2014-01-01

    Biological and other natural processes have always been a source of inspiration for computer science and information technology. Many emerging problem solving techniques integrate advanced evolution and cooperation strategies, encompassing a range of spatio-temporal scales for visionary conceptualization of evolutionary computation. This book is a collection of research works presented in the VI International Workshop on Nature Inspired Cooperative Strategies for Optimization (NICSO) held in Canterbury, UK. Previous editions of NICSO were held in Granada, Spain (2006 & 2010), Acireale, Italy (2007), Tenerife, Spain (2008), and Cluj-Napoca, Romania (2011). NICSO 2013 and this book provides a place where state-of-the-art research, latest ideas and emerging areas of nature inspired cooperative strategies for problem solving are vigorously discussed and exchanged among the scientific community. The breadth and variety of articles in this book report on nature inspired methods and applications such as Swarm In...

  11. Nuclear Power Plant Outage Optimization Strategy. 2016 Edition

    2016-10-01

    This publication is an update of IAEA-TECDOC-1315, Nuclear Power Plant Outage Optimisation Strategy, which was published in 2002, and aims to communicate good outage management practices in a manner that can be used by operators and utilities in Member States. Nuclear power plant outage management is a key factor for safe and economic nuclear power plant performance. This publication discusses plant outage strategy and how this strategy is actually implemented. The main areas that are important for outage optimization that were identified by the utilities and government organizations participating in this report are: 1) organization and management; 2) outage planning and preparation; 3) outage execution; 4) safety outage review; and 5) counter measures to avoid the extension of outages and to facilitate the work in forced outages. Good outage management practices cover many different areas of work and this publication aims to communicate these good practices in a way that they can be used effectively by operators and utilities

  12. Evaluation of optimization strategies and the effect of initial conditions on IMAT optimization using a leaf position optimization algorithm

    Oliver, Mike; Jensen, Michael; Chen, Jeff; Wong, Eugene

    2009-01-01

    Intensity-modulated arc therapy (IMAT) is a rotational variant of intensity-modulated radiation therapy (IMRT) that can be implemented with or without angular dose rate variation. The purpose of this study is to assess optimization strategies and initial conditions using a leaf position optimization (LPO) algorithm altered for variable dose rate IMAT. A concave planning target volume (PTV) with a central cylindrical organ at risk (OAR) was used in this study. The initial IMAT arcs were approximated by multiple static beams at 5 deg. angular increments where multi-leaf collimator (MLC) leaf positions were determined from the beam's eye view to irradiate the PTV but avoid the OAR. For the optimization strategy, two arcs with arc ranges of 280 deg. and 150 deg. were employed and plans were created using LPO alone, variable dose rate optimization (VDRO) alone, simultaneous LPO and VDRO and sequential combinations of these strategies. To assess the MLC initialization effect, three single 360 deg. arc plans with different initial MLC configurations were generated using the simultaneous LPO and VDRO. The effect of changing optimization degrees of freedom was investigated by employing 3 deg., 5 deg. and 10 deg. angular sampling intervals for the two 280 deg., two 150 deg. and single arc plans using LPO and VDRO. The objective function value, a conformity index, a dose homogeneity index, mean dose to OAR and normal tissues were computed and used to evaluate the treatment plans. This study shows that the best optimization strategy for a concave target is to use simultaneous MLC LPO and VDRO. We found that the optimization result is sensitive to the choice of initial MLC aperture shapes suggesting that an LPO-based IMAT plan may not be able to overcome local minima for this geometry. In conclusion, simultaneous MLC leaf position and VDRO are needed with the most appropriate initial conditions (MLC positions, arc ranges and number of arcs) for IMAT.

  13. Optimal Dynamic Strategies for Index Tracking and Algorithmic Trading

    Ward, Brian

    In this thesis we study dynamic strategies for index tracking and algorithmic trading. Tracking problems have become ever more important in Financial Engineering as investors seek to precisely control their portfolio risks and exposures over different time horizons. This thesis analyzes various tracking problems and elucidates the tracking errors and strategies one can employ to minimize those errors and maximize profit. In Chapters 2 and 3, we study the empirical tracking properties of exchange traded funds (ETFs), leveraged ETFs (LETFs), and futures products related to spot gold and the Chicago Board Option Exchange (CBOE) Volatility Index (VIX), respectively. These two markets provide interesting and differing examples for understanding index tracking. We find that static strategies work well in the nonleveraged case for gold, but fail to track well in the corresponding leveraged case. For VIX, tracking via neither ETFs, nor futures\\ portfolios succeeds, even in the nonleveraged case. This motivates the need for dynamic strategies, some of which we construct in these two chapters and further expand on in Chapter 4. There, we analyze a framework for index tracking and risk exposure control through financial derivatives. We derive a tracking condition that restricts our exposure choices and also define a slippage process that characterizes the deviations from the index over longer horizons. The framework is applied to a number of models, for example, Black Scholes model and Heston model for equity index tracking, as well as the Square Root (SQR) model and the Concatenated Square Root (CSQR) model for VIX tracking. By specifying how each of these models fall into our framework, we are able to understand the tracking errors in each of these models. Finally, Chapter 5 analyzes a tracking problem of a different kind that arises in algorithmic trading: schedule following for optimal execution. We formulate and solve a stochastic control problem to obtain the optimal

  14. Cost-effectiveness analysis of optimal strategy for tumor treatment

    Pang, Liuyong; Zhao, Zhong; Song, Xinyu

    2016-01-01

    We propose and analyze an antitumor model with combined immunotherapy and chemotherapy. Firstly, we explore the treatment effects of single immunotherapy and single chemotherapy, respectively. Results indicate that neither immunotherapy nor chemotherapy alone are adequate to cure a tumor. Hence, we apply optimal theory to investigate how the combination of immunotherapy and chemotherapy should be implemented, for a certain time period, in order to reduce the number of tumor cells, while minimizing the implementation cost of the treatment strategy. Secondly, we establish the existence of the optimality system and use Pontryagin’s Maximum Principle to characterize the optimal levels of the two treatment measures. Furthermore, we calculate the incremental cost-effectiveness ratios to analyze the cost-effectiveness of all possible combinations of the two treatment measures. Finally, numerical results show that the combination of immunotherapy and chemotherapy is the most cost-effective strategy for tumor treatment, and able to eliminate the entire tumor with size 4.470 × 10"8 in a year.

  15. Optimal knockout strategies in genome-scale metabolic networks using particle swarm optimization.

    Nair, Govind; Jungreuthmayer, Christian; Zanghellini, Jürgen

    2017-02-01

    Knockout strategies, particularly the concept of constrained minimal cut sets (cMCSs), are an important part of the arsenal of tools used in manipulating metabolic networks. Given a specific design, cMCSs can be calculated even in genome-scale networks. We would however like to find not only the optimal intervention strategy for a given design but the best possible design too. Our solution (PSOMCS) is to use particle swarm optimization (PSO) along with the direct calculation of cMCSs from the stoichiometric matrix to obtain optimal designs satisfying multiple objectives. To illustrate the working of PSOMCS, we apply it to a toy network. Next we show its superiority by comparing its performance against other comparable methods on a medium sized E. coli core metabolic network. PSOMCS not only finds solutions comparable to previously published results but also it is orders of magnitude faster. Finally, we use PSOMCS to predict knockouts satisfying multiple objectives in a genome-scale metabolic model of E. coli and compare it with OptKnock and RobustKnock. PSOMCS finds competitive knockout strategies and designs compared to other current methods and is in some cases significantly faster. It can be used in identifying knockouts which will force optimal desired behaviors in large and genome scale metabolic networks. It will be even more useful as larger metabolic models of industrially relevant organisms become available.

  16. Optimal Bidding Strategy for Renewable Microgrid with Active Network Management

    Seung Wan Kim

    2016-01-01

    Full Text Available Active Network Management (ANM enables a microgrid to optimally dispatch the active/reactive power of its Renewable Distributed Generation (RDG and Battery Energy Storage System (BESS units in real time. Thus, a microgrid with high penetration of RDGs can handle their uncertainties and variabilities to achieve the stable operation using ANM. However, the actual power flow in the line connecting the main grid and microgrid may deviate significantly from the day-ahead bids if the bids are determined without consideration of the real-time adjustment through ANM, which will lead to a substantial imbalance cost. Therefore, this study proposes a formulation for obtaining an optimal bidding which reflects the change of power flow in the connecting line by real-time adjustment using ANM. The proposed formulation maximizes the expected profit of the microgrid considering various network and physical constraints. The effectiveness of the proposed bidding strategy is verified through the simulations with a 33-bus test microgrid. The simulation results show that the proposed bidding strategy improves the expected operating profit by reducing the imbalance cost to a greater degree compared to the basic bidding strategy without consideration of ANM.

  17. Cost Effectiveness Analysis of Optimal Malaria Control Strategies in Kenya

    Gabriel Otieno

    2016-03-01

    Full Text Available Malaria remains a leading cause of mortality and morbidity among the children under five and pregnant women in sub-Saharan Africa, but it is preventable and controllable provided current recommended interventions are properly implemented. Better utilization of malaria intervention strategies will ensure the gain for the value for money and producing health improvements in the most cost effective way. The purpose of the value for money drive is to develop a better understanding (and better articulation of costs and results so that more informed, evidence-based choices could be made. Cost effectiveness analysis is carried out to inform decision makers on how to determine where to allocate resources for malaria interventions. This study carries out cost effective analysis of one or all possible combinations of the optimal malaria control strategies (Insecticide Treated Bednets—ITNs, Treatment, Indoor Residual Spray—IRS and Intermittent Preventive Treatment for Pregnant Women—IPTp for the four different transmission settings in order to assess the extent to which the intervention strategies are beneficial and cost effective. For the four different transmission settings in Kenya the optimal solution for the 15 strategies and their associated effectiveness are computed. Cost-effective analysis using Incremental Cost Effectiveness Ratio (ICER was done after ranking the strategies in order of the increasing effectiveness (total infections averted. The findings shows that for the endemic regions the combination of ITNs, IRS, and IPTp was the most cost-effective of all the combined strategies developed in this study for malaria disease control and prevention; for the epidemic prone areas is the combination of the treatment and IRS; for seasonal areas is the use of ITNs plus treatment; and for the low risk areas is the use of treatment only. Malaria transmission in Kenya can be minimized through tailor-made intervention strategies for malaria control

  18. Testing of Strategies for the Acceleration of the Cost Optimization

    Ponciroli, Roberto [Argonne National Lab. (ANL), Argonne, IL (United States); Vilim, Richard B. [Argonne National Lab. (ANL), Argonne, IL (United States)

    2017-08-31

    The general problem addressed in the Nuclear-Renewable Hybrid Energy System (N-R HES) project is finding the optimum economical dispatch (ED) and capacity planning solutions for the hybrid energy systems. In the present test-problem configuration, the N-R HES unit is composed of three electrical power-generating components, i.e. the Balance of Plant (BOP), the Secondary Energy Source (SES), and the Energy Storage (ES). In addition, there is an Industrial Process (IP), which is devoted to hydrogen generation. At this preliminary stage, the goal is to find the power outputs of each one of the N-R HES unit components (BOP, SES, ES) and the IP hydrogen production level that maximizes the unit profit by simultaneously satisfying individual component operational constraints. The optimization problem is meant to be solved in the Risk Analysis Virtual Environment (RAVEN) framework. The dynamic response of the N-R HES unit components is simulated by using dedicated object-oriented models written in the Modelica modeling language. Though this code coupling provides for very accurate predictions, the ensuing optimization problem is characterized by a very large number of solution variables. To ease the computational burden and to improve the path to a converged solution, a method to better estimate the initial guess for the optimization problem solution was developed. The proposed approach led to the definition of a suitable Monte Carlo-based optimization algorithm (called the preconditioner), which provides an initial guess for the optimal N-R HES power dispatch and the optimal installed capacity for each one of the unit components. The preconditioner samples a set of stochastic power scenarios for each one of the N-R HES unit components, and then for each of them the corresponding value of a suitably defined cost function is evaluated. After having simulated a sufficient number of power histories, the configuration which ensures the highest profit is selected as the optimal

  19. Issues and Strategies in Solving Multidisciplinary Optimization Problems

    Patnaik, Surya

    2013-01-01

    Optimization research at NASA Glenn Research Center has addressed the design of structures, aircraft and airbreathing propulsion engines. The accumulated multidisciplinary design activity is collected under a testbed entitled COMETBOARDS. Several issues were encountered during the solution of the problems. Four issues and the strategies adapted for their resolution are discussed. This is followed by a discussion on analytical methods that is limited to structural design application. An optimization process can lead to an inefficient local solution. This deficiency was encountered during design of an engine component. The limitation was overcome through an augmentation of animation into optimization. Optimum solutions obtained were infeasible for aircraft and airbreathing propulsion engine problems. Alleviation of this deficiency required a cascading of multiple algorithms. Profile optimization of a beam produced an irregular shape. Engineering intuition restored the regular shape for the beam. The solution obtained for a cylindrical shell by a subproblem strategy converged to a design that can be difficult to manufacture. Resolution of this issue remains a challenge. The issues and resolutions are illustrated through a set of problems: Design of an engine component, Synthesis of a subsonic aircraft, Operation optimization of a supersonic engine, Design of a wave-rotor-topping device, Profile optimization of a cantilever beam, and Design of a cylindrical shell. This chapter provides a cursory account of the issues. Cited references provide detailed discussion on the topics. Design of a structure can also be generated by traditional method and the stochastic design concept. Merits and limitations of the three methods (traditional method, optimization method and stochastic concept) are illustrated. In the traditional method, the constraints are manipulated to obtain the design and weight is back calculated. In design optimization, the weight of a structure becomes the

  20. Automatic Construction and Global Optimization of a Multisentiment Lexicon

    Xiaoping Yang

    2016-01-01

    Full Text Available Manual annotation of sentiment lexicons costs too much labor and time, and it is also difficult to get accurate quantification of emotional intensity. Besides, the excessive emphasis on one specific field has greatly limited the applicability of domain sentiment lexicons (Wang et al., 2010. This paper implements statistical training for large-scale Chinese corpus through neural network language model and proposes an automatic method of constructing a multidimensional sentiment lexicon based on constraints of coordinate offset. In order to distinguish the sentiment polarities of those words which may express either positive or negative meanings in different contexts, we further present a sentiment disambiguation algorithm to increase the flexibility of our lexicon. Lastly, we present a global optimization framework that provides a unified way to combine several human-annotated resources for learning our 10-dimensional sentiment lexicon SentiRuc. Experiments show the superior performance of SentiRuc lexicon in category labeling test, intensity labeling test, and sentiment classification tasks. It is worth mentioning that, in intensity label test, SentiRuc outperforms the second place by 21 percent.

  1. A DE-Based Scatter Search for Global Optimization Problems

    Kun Li

    2015-01-01

    Full Text Available This paper proposes a hybrid scatter search (SS algorithm for continuous global optimization problems by incorporating the evolution mechanism of differential evolution (DE into the reference set updated procedure of SS to act as the new solution generation method. This hybrid algorithm is called a DE-based SS (SSDE algorithm. Since different kinds of mutation operators of DE have been proposed in the literature and they have shown different search abilities for different kinds of problems, four traditional mutation operators are adopted in the hybrid SSDE algorithm. To adaptively select the mutation operator that is most appropriate to the current problem, an adaptive mechanism for the candidate mutation operators is developed. In addition, to enhance the exploration ability of SSDE, a reinitialization method is adopted to create a new population and subsequently construct a new reference set whenever the search process of SSDE is trapped in local optimum. Computational experiments on benchmark problems show that the proposed SSDE is competitive or superior to some state-of-the-art algorithms in the literature.

  2. Optimal control applied to the control strategy of a parallel hybrid vehicle; Commande optimale appliquee a la strategie de commande d'un vehicule hybride parallele

    Delprat, S.; Guerra, T.M. [Universite de Valenciennes et du Hainaut-Cambresis, LAMIH UMR CNRS 8530, 59 - Valenciennes (France); Rimaux, J. [PSA Peugeot Citroen, DRIA/SARA/EEES, 78 - Velizy Villacoublay (France); Paganelli, G. [Center for Automotive Research, Ohio (United States)

    2002-07-01

    Control strategies are algorithms that calculate the power repartition between the engine and the motor of an hybrid vehicle in order to minimize the fuel consumption and/or emissions. Some algorithms are devoted to real time application whereas others are designed for global optimization in stimulation. The last ones provide solutions which can be used to evaluate the performances of a given hybrid vehicle or a given real time control strategy. The control strategy problem is firstly written into the form of an optimization under constraints problem. A solution based on optimal control is proposed. Results are given for the European Normalized Cycle and a parallel single shaft hybrid vehicle built at the LAMIH (France). (authors)

  3. Strategies for Optimizing Algal Biology for Enhanced Biomass Production

    Barry, Amanda N.; Starkenburg, Shawn R.; Sayre, Richard T., E-mail: rsayre@newmexicoconsortium.org [Los Alamos National Laboratory, New Mexico Consortium, Los Alamos, NM (United States)

    2015-02-02

    One of the most environmentally sustainable ways to produce high-energy density (oils) feed stocks for the production of liquid transportation fuels is from biomass. Photosynthetic carbon capture combined with biomass combustion (point source) and subsequent carbon capture and sequestration has also been proposed in the intergovernmental panel on climate change report as one of the most effective and economical strategies to remediate atmospheric greenhouse gases. To maximize photosynthetic carbon capture efficiency and energy-return-on-investment, we must develop biomass production systems that achieve the greatest yields with the lowest inputs. Numerous studies have demonstrated that microalgae have among the greatest potentials for biomass production. This is in part due to the fact that all alga cells are photoautotrophic, they have active carbon concentrating mechanisms to increase photosynthetic productivity, and all the biomass is harvestable unlike plants. All photosynthetic organisms, however, convert only a fraction of the solar energy they capture into chemical energy (reduced carbon or biomass). To increase aerial carbon capture rates and biomass productivity, it will be necessary to identify the most robust algal strains and increase their biomass production efficiency often by genetic manipulation. We review recent large-scale efforts to identify the best biomass producing strains and metabolic engineering strategies to improve aerial productivity. These strategies include optimization of photosynthetic light-harvesting antenna size to increase energy capture and conversion efficiency and the potential development of advanced molecular breeding techniques. To date, these strategies have resulted in up to twofold increases in biomass productivity.

  4. Strategies for Optimizing Algal Biology for Enhanced Biomass Production

    Barry, Amanda N.; Starkenburg, Shawn R.; Sayre, Richard T.

    2015-01-01

    One of the most environmentally sustainable ways to produce high-energy density (oils) feed stocks for the production of liquid transportation fuels is from biomass. Photosynthetic carbon capture combined with biomass combustion (point source) and subsequent carbon capture and sequestration has also been proposed in the intergovernmental panel on climate change report as one of the most effective and economical strategies to remediate atmospheric greenhouse gases. To maximize photosynthetic carbon capture efficiency and energy-return-on-investment, we must develop biomass production systems that achieve the greatest yields with the lowest inputs. Numerous studies have demonstrated that microalgae have among the greatest potentials for biomass production. This is in part due to the fact that all alga cells are photoautotrophic, they have active carbon concentrating mechanisms to increase photosynthetic productivity, and all the biomass is harvestable unlike plants. All photosynthetic organisms, however, convert only a fraction of the solar energy they capture into chemical energy (reduced carbon or biomass). To increase aerial carbon capture rates and biomass productivity, it will be necessary to identify the most robust algal strains and increase their biomass production efficiency often by genetic manipulation. We review recent large-scale efforts to identify the best biomass producing strains and metabolic engineering strategies to improve aerial productivity. These strategies include optimization of photosynthetic light-harvesting antenna size to increase energy capture and conversion efficiency and the potential development of advanced molecular breeding techniques. To date, these strategies have resulted in up to twofold increases in biomass productivity.

  5. Multi-Objective Optimization of a Hybrid ESS Based on Optimal Energy Management Strategy for LHDs

    Jiajun Liu

    2017-10-01

    Full Text Available Energy storage systems (ESS play an important role in the performance of mining vehicles. A hybrid ESS combining both batteries (BTs and supercapacitors (SCs is one of the most promising solutions. As a case study, this paper discusses the optimal hybrid ESS sizing and energy management strategy (EMS of 14-ton underground load-haul-dump vehicles (LHDs. Three novel contributions are added to the relevant literature. First, a multi-objective optimization is formulated regarding energy consumption and the total cost of a hybrid ESS, which are the key factors of LHDs, and a battery capacity degradation model is used. During the process, dynamic programming (DP-based EMS is employed to obtain the optimal energy consumption and hybrid ESS power profiles. Second, a 10-year life cycle cost model of a hybrid ESS for LHDs is established to calculate the total cost, including capital cost, operating cost, and replacement cost. According to the optimization results, three solutions chosen from the Pareto front are compared comprehensively, and the optimal one is selected. Finally, the optimal and battery-only options are compared quantitatively using the same objectives, and the hybrid ESS is found to be a more economical and efficient option.

  6. Rebuilding the Arab Economies: New Regional and Global Strategies

    Laura - Ramona BENCHEA

    2015-12-01

    Full Text Available The Arab countries are facing one of their most difficult periods of the modern history. The popular uprisings which broke out at the beginning of 2011 in Tunisia and then spread to Egypt, Libya, Morocco, Jordan, Bahrain and Syria, reflect profound economic and social hardships, but also major uncertainties regarding the political perspectives of these countries. The political transition carried out by several Arab countries could represent an incentive for profound economic reorganization and structural change all over the region. The aim of this paper is to assess the structural economic challenges the Arab countries had been confronted with over many decades and to identify possible regional and global strategies for economic development.

  7. Identifying the preferred subset of enzymatic profiles in nonlinear kinetic metabolic models via multiobjective global optimization and Pareto filters.

    Carlos Pozo

    Full Text Available Optimization models in metabolic engineering and systems biology focus typically on optimizing a unique criterion, usually the synthesis rate of a metabolite of interest or the rate of growth. Connectivity and non-linear regulatory effects, however, make it necessary to consider multiple objectives in order to identify useful strategies that balance out different metabolic issues. This is a fundamental aspect, as optimization of maximum yield in a given condition may involve unrealistic values in other key processes. Due to the difficulties associated with detailed non-linear models, analysis using stoichiometric descriptions and linear optimization methods have become rather popular in systems biology. However, despite being useful, these approaches fail in capturing the intrinsic nonlinear nature of the underlying metabolic systems and the regulatory signals involved. Targeting more complex biological systems requires the application of global optimization methods to non-linear representations. In this work we address the multi-objective global optimization of metabolic networks that are described by a special class of models based on the power-law formalism: the generalized mass action (GMA representation. Our goal is to develop global optimization methods capable of efficiently dealing with several biological criteria simultaneously. In order to overcome the numerical difficulties of dealing with multiple criteria in the optimization, we propose a heuristic approach based on the epsilon constraint method that reduces the computational burden of generating a set of Pareto optimal alternatives, each achieving a unique combination of objectives values. To facilitate the post-optimal analysis of these solutions and narrow down their number prior to being tested in the laboratory, we explore the use of Pareto filters that identify the preferred subset of enzymatic profiles. We demonstrate the usefulness of our approach by means of a case study

  8. Identifying the preferred subset of enzymatic profiles in nonlinear kinetic metabolic models via multiobjective global optimization and Pareto filters.

    Pozo, Carlos; Guillén-Gosálbez, Gonzalo; Sorribas, Albert; Jiménez, Laureano

    2012-01-01

    Optimization models in metabolic engineering and systems biology focus typically on optimizing a unique criterion, usually the synthesis rate of a metabolite of interest or the rate of growth. Connectivity and non-linear regulatory effects, however, make it necessary to consider multiple objectives in order to identify useful strategies that balance out different metabolic issues. This is a fundamental aspect, as optimization of maximum yield in a given condition may involve unrealistic values in other key processes. Due to the difficulties associated with detailed non-linear models, analysis using stoichiometric descriptions and linear optimization methods have become rather popular in systems biology. However, despite being useful, these approaches fail in capturing the intrinsic nonlinear nature of the underlying metabolic systems and the regulatory signals involved. Targeting more complex biological systems requires the application of global optimization methods to non-linear representations. In this work we address the multi-objective global optimization of metabolic networks that are described by a special class of models based on the power-law formalism: the generalized mass action (GMA) representation. Our goal is to develop global optimization methods capable of efficiently dealing with several biological criteria simultaneously. In order to overcome the numerical difficulties of dealing with multiple criteria in the optimization, we propose a heuristic approach based on the epsilon constraint method that reduces the computational burden of generating a set of Pareto optimal alternatives, each achieving a unique combination of objectives values. To facilitate the post-optimal analysis of these solutions and narrow down their number prior to being tested in the laboratory, we explore the use of Pareto filters that identify the preferred subset of enzymatic profiles. We demonstrate the usefulness of our approach by means of a case study that optimizes the

  9. Implementation Strategy for a Global Solar and Wind Atlas

    NONE

    2012-01-15

    In July 2009, Major Economies Forum leaders met to prepare for the COP 15 Copenhagen Conference that took place later that year. At this occasion the Major Economies Forum Global Partnership f or low carbon and climate-friendly technology was founded and Technology Action Plans (TAPs) for ten key low-carbon technologies were drafted. At that juncture Denmark, Germany and Spain took on the responsibility for drafting TAPs for Solar and Wind Energy Technologies. The TAPs were then consolidated and presented at COP 15 that would later take place in December in Copenhagen. Since then, countries that led the development of the Action Plans have started their implementation. During a first Clean Energy Ministerial (CEM) in July 2010 in Washington on the invitation of Steven Chu, US Secretary of Energy, several initiatives were launched. Denmark, Germany and Spain took the lead in the implementation of the TAPs for Solar and Wind Technologies and initiated the Multilateral Working Group on Solar and Wind Energy Technologies (MWGSW). Several countries joined the working group in Washington and afterwards. In two international workshops in Bonn (June 2010) and Madrid (November 2010) and in meetings during the first CEM in Washington (July 2010) and the second CEM in Abu Dhabi (April 2011) the Multilateral Working Group made substantial progress in the two initial fields of action: (1) the Development of a Global Solar and Wind Atlas; and (2) the Development of a Long-term Strategy on Joint Capacity Building. Discussion papers on the respective topics were elaborated involving the Working Group's member countries as well as various international institutions. This led to concrete proposals for several pilot activities in both fields of action. After further specifying key elements of the suggested projects in two expert workshops in spring 2011, the Multilateral Working Group convened for a third international workshop in Copenhagen, Denmark, to discuss the project

  10. Improving the automated optimization of profile extrusion dies by applying appropriate optimization areas and strategies

    Hopmann, Ch.; Windeck, C.; Kurth, K.; Behr, M.; Siegbert, R.; Elgeti, S.

    2014-05-01

    The rheological design of profile extrusion dies is one of the most challenging tasks in die design. As no analytical solution is available, the quality and the development time for a new design highly depend on the empirical knowledge of the die manufacturer. Usually, prior to start production several time-consuming, iterative running-in trials need to be performed to check the profile accuracy and the die geometry is reworked. An alternative are numerical flow simulations. These simulations enable to calculate the melt flow through a die so that the quality of the flow distribution can be analyzed. The objective of a current research project is to improve the automated optimization of profile extrusion dies. Special emphasis is put on choosing a convenient starting geometry and parameterization, which enable for possible deformations. In this work, three commonly used design features are examined with regard to their influence on the optimization results. Based on the results, a strategy is derived to select the most relevant areas of the flow channels for the optimization. For these characteristic areas recommendations are given concerning an efficient parameterization setup that still enables adequate deformations of the flow channel geometry. Exemplarily, this approach is applied to a L-shaped profile with different wall thicknesses. The die is optimized automatically and simulation results are qualitatively compared with experimental results. Furthermore, the strategy is applied to a complex extrusion die of a floor skirting profile to prove the universal adaptability.

  11. Steady-state global optimization of metabolic non-linear dynamic models through recasting into power-law canonical models.

    Pozo, Carlos; Marín-Sanguino, Alberto; Alves, Rui; Guillén-Gosálbez, Gonzalo; Jiménez, Laureano; Sorribas, Albert

    2011-08-25

    Design of newly engineered microbial strains for biotechnological purposes would greatly benefit from the development of realistic mathematical models for the processes to be optimized. Such models can then be analyzed and, with the development and application of appropriate optimization techniques, one could identify the modifications that need to be made to the organism in order to achieve the desired biotechnological goal. As appropriate models to perform such an analysis are necessarily non-linear and typically non-convex, finding their global optimum is a challenging task. Canonical modeling techniques, such as Generalized Mass Action (GMA) models based on the power-law formalism, offer a possible solution to this problem because they have a mathematical structure that enables the development of specific algorithms for global optimization. Based on the GMA canonical representation, we have developed in previous works a highly efficient optimization algorithm and a set of related strategies for understanding the evolution of adaptive responses in cellular metabolism. Here, we explore the possibility of recasting kinetic non-linear models into an equivalent GMA model, so that global optimization on the recast GMA model can be performed. With this technique, optimization is greatly facilitated and the results are transposable to the original non-linear problem. This procedure is straightforward for a particular class of non-linear models known as Saturable and Cooperative (SC) models that extend the power-law formalism to deal with saturation and cooperativity. Our results show that recasting non-linear kinetic models into GMA models is indeed an appropriate strategy that helps overcoming some of the numerical difficulties that arise during the global optimization task.

  12. Steady-state global optimization of metabolic non-linear dynamic models through recasting into power-law canonical models

    Sorribas Albert

    2011-08-01

    Full Text Available Abstract Background Design of newly engineered microbial strains for biotechnological purposes would greatly benefit from the development of realistic mathematical models for the processes to be optimized. Such models can then be analyzed and, with the development and application of appropriate optimization techniques, one could identify the modifications that need to be made to the organism in order to achieve the desired biotechnological goal. As appropriate models to perform such an analysis are necessarily non-linear and typically non-convex, finding their global optimum is a challenging task. Canonical modeling techniques, such as Generalized Mass Action (GMA models based on the power-law formalism, offer a possible solution to this problem because they have a mathematical structure that enables the development of specific algorithms for global optimization. Results Based on the GMA canonical representation, we have developed in previous works a highly efficient optimization algorithm and a set of related strategies for understanding the evolution of adaptive responses in cellular metabolism. Here, we explore the possibility of recasting kinetic non-linear models into an equivalent GMA model, so that global optimization on the recast GMA model can be performed. With this technique, optimization is greatly facilitated and the results are transposable to the original non-linear problem. This procedure is straightforward for a particular class of non-linear models known as Saturable and Cooperative (SC models that extend the power-law formalism to deal with saturation and cooperativity. Conclusions Our results show that recasting non-linear kinetic models into GMA models is indeed an appropriate strategy that helps overcoming some of the numerical difficulties that arise during the global optimization task.

  13. Web malware spread modelling and optimal control strategies

    Liu, Wanping; Zhong, Shouming

    2017-02-01

    The popularity of the Web improves the growth of web threats. Formulating mathematical models for accurate prediction of malicious propagation over networks is of great importance. The aim of this paper is to understand the propagation mechanisms of web malware and the impact of human intervention on the spread of malicious hyperlinks. Considering the characteristics of web malware, a new differential epidemic model which extends the traditional SIR model by adding another delitescent compartment is proposed to address the spreading behavior of malicious links over networks. The spreading threshold of the model system is calculated, and the dynamics of the model is theoretically analyzed. Moreover, the optimal control theory is employed to study malware immunization strategies, aiming to keep the total economic loss of security investment and infection loss as low as possible. The existence and uniqueness of the results concerning the optimality system are confirmed. Finally, numerical simulations show that the spread of malware links can be controlled effectively with proper control strategy of specific parameter choice.

  14. An Improved Harmony Search Based on Teaching-Learning Strategy for Unconstrained Optimization Problems

    Shouheng Tuo

    2013-01-01

    Full Text Available Harmony search (HS algorithm is an emerging population-based metaheuristic algorithm, which is inspired by the music improvisation process. The HS method has been developed rapidly and applied widely during the past decade. In this paper, an improved global harmony search algorithm, named harmony search based on teaching-learning (HSTL, is presented for high dimension complex optimization problems. In HSTL algorithm, four strategies (harmony memory consideration, teaching-learning strategy, local pitch adjusting, and random mutation are employed to maintain the proper balance between convergence and population diversity, and dynamic strategy is adopted to change the parameters. The proposed HSTL algorithm is investigated and compared with three other state-of-the-art HS optimization algorithms. Furthermore, to demonstrate the robustness and convergence, the success rate and convergence analysis is also studied. The experimental results of 31 complex benchmark functions demonstrate that the HSTL method has strong convergence and robustness and has better balance capacity of space exploration and local exploitation on high dimension complex optimization problems.

  15. Multi-infill strategy for kriging models used in variable fidelity optimization

    Chao SONG

    2018-03-01

    Full Text Available In this paper, a computationally efficient optimization method for aerodynamic design has been developed. The low-fidelity model and the multi-infill strategy are utilized in this approach. Low-fidelity data is employed to provide a good global trend for model prediction, and multiple sample points chosen by different infill criteria in each updating cycle are used to enhance the exploitation and exploration ability of the optimization approach. Take the advantages of low-fidelity model and the multi-infill strategy, and no initial sample for the high-fidelity model is needed. This approach is applied to an airfoil design case and a high-dimensional wing design case. It saves a large number of high-fidelity function evaluations for initial model construction. What’s more, faster reduction of an aerodynamic function is achieved, when compared to ordinary kriging using the multi-infill strategy and variable-fidelity model using single infill criterion. The results indicate that the developed approach has a promising application to efficient aerodynamic design when high-fidelity analyses are involved. Keywords: Aerodynamics, Infill criteria, Kriging models, Multi-infill, Optimization

  16. Multi-objective component sizing based on optimal energy management strategy of fuel cell electric vehicles

    Xu, Liangfei; Mueller, Clemens David; Li, Jianqiu; Ouyang, Minggao; Hu, Zunyan

    2015-01-01

    Highlights: • A non-linear model regarding fuel economy and system durability of FCEV. • A two-step algorithm for a quasi-optimal solution to a multi-objective problem. • Optimal parameters for DP algorithm considering accuracy and calculating time. • Influences of FC power and battery capacity on system performance. - Abstract: A typical topology of a proton electrolyte membrane (PEM) fuel cell electric vehicle contains at least two power sources, a fuel cell system (FCS) and a lithium battery package. The FCS provides stationary power, and the battery delivers dynamic power. In this paper, we report on the multi-objective optimization problem of powertrain parameters for a pre-defined driving cycle regarding fuel economy and system durability. We introduce the dynamic model for the FCEV. We take into consideration equations not only for fuel economy but also for system durability. In addition, we define a multi-objective optimization problem, and find a quasi-optimal solution using a two-loop framework. In the inside loop, for each group of powertrain parameters, a global optimal energy management strategy based on dynamic programming (DP) is exploited. We optimize coefficients for the DP algorithm to reduce calculating time as well as to maintain accuracy. For the outside loop, we compare the results of all the groups with each other, and choose the Pareto optimal solution based on a compromise of fuel economy and system durability. Simulation results show that for a “China city bus typical cycle,” a battery capacity of 150 Ah and an FCS maximal net output power of 40 kW are optimal for the fuel economy and system durability of a fuel cell city bus.

  17. Regional strategies for the accelerating global problem of groundwater depletion

    Aeschbach-Hertig, Werner; Gleeson, Tom

    2012-12-01

    Groundwater--the world's largest freshwater resource--is critically important for irrigated agriculture and hence for global food security. Yet depletion is widespread in large groundwater systems in both semi-arid and humid regions of the world. Excessive extraction for irrigation where groundwater is slowly renewed is the main cause of the depletion, and climate change has the potential to exacerbate the problem in some regions. Globally aggregated groundwater depletion contributes to sea-level rise, and has accelerated markedly since the mid-twentieth century. But its impacts on water resources are more obvious at the regional scale, for example in agriculturally important parts of India, China and the United States. Food production in such regions can only be made sustainable in the long term if groundwater levels are stabilized. To this end, a transformation is required in how we value, manage and characterize groundwater systems. Technical approaches--such as water diversion, artificial groundwater recharge and efficient irrigation--have failed to balance regional groundwater budgets. They need to be complemented by more comprehensive strategies that are adapted to the specific social, economic, political and environmental settings of each region.

  18. Model-Based Optimization of Velocity Strategy for Lightweight Electric Racing Cars

    Mirosław Targosz

    2018-01-01

    Full Text Available The article presents a method for optimizing driving strategies aimed at minimizing energy consumption while driving. The method was developed for the needs of an electric powered racing vehicle built for the purposes of the Shell Eco-marathon (SEM, the most famous and largest race of energy efficient vehicles. Model-based optimization was used to determine the driving strategy. The numerical model was elaborated in Simulink environment, which includes both the electric vehicle model and the environment, i.e., the race track as well as the vehicle environment and the atmospheric conditions. The vehicle model itself includes vehicle dynamic model, numerical model describing issues concerning resistance of rolling tire, resistance of the propulsion system, aerodynamic phenomena, model of the electric motor, and control system. For the purpose of identifying design and functional features of individual subassemblies and components, numerical and stand tests were carried out. The model itself was tested on the research tracks to tune the model and determine the calculation parameters. The evolutionary algorithms, which are available in the MATLAB Global Optimization Toolbox, were used for optimization. In the race conditions, the model was verified during SEM races in Rotterdam where the race vehicle scored the result consistent with the results of simulation calculations. In the following years, the experience gathered by the team gave us the vice Championship in the SEM 2016 in London.

  19. Many-Objective Particle Swarm Optimization Using Two-Stage Strategy and Parallel Cell Coordinate System.

    Hu, Wang; Yen, Gary G; Luo, Guangchun

    2017-06-01

    It is a daunting challenge to balance the convergence and diversity of an approximate Pareto front in a many-objective optimization evolutionary algorithm. A novel algorithm, named many-objective particle swarm optimization with the two-stage strategy and parallel cell coordinate system (PCCS), is proposed in this paper to improve the comprehensive performance in terms of the convergence and diversity. In the proposed two-stage strategy, the convergence and diversity are separately emphasized at different stages by a single-objective optimizer and a many-objective optimizer, respectively. A PCCS is exploited to manage the diversity, such as maintaining a diverse archive, identifying the dominance resistant solutions, and selecting the diversified solutions. In addition, a leader group is used for selecting the global best solutions to balance the exploitation and exploration of a population. The experimental results illustrate that the proposed algorithm outperforms six chosen state-of-the-art designs in terms of the inverted generational distance and hypervolume over the DTLZ test suite.

  20. Using Chemical Reaction Kinetics to Predict Optimal Antibiotic Treatment Strategies.

    Abel Zur Wiesch, Pia; Clarelli, Fabrizio; Cohen, Ted

    2017-01-01

    Identifying optimal dosing of antibiotics has proven challenging-some antibiotics are most effective when they are administered periodically at high doses, while others work best when minimizing concentration fluctuations. Mechanistic explanations for why antibiotics differ in their optimal dosing are lacking, limiting our ability to predict optimal therapy and leading to long and costly experiments. We use mathematical models that describe both bacterial growth and intracellular antibiotic-target binding to investigate the effects of fluctuating antibiotic concentrations on individual bacterial cells and bacterial populations. We show that physicochemical parameters, e.g. the rate of drug transmembrane diffusion and the antibiotic-target complex half-life are sufficient to explain which treatment strategy is most effective. If the drug-target complex dissociates rapidly, the antibiotic must be kept constantly at a concentration that prevents bacterial replication. If antibiotics cross bacterial cell envelopes slowly to reach their target, there is a delay in the onset of action that may be reduced by increasing initial antibiotic concentration. Finally, slow drug-target dissociation and slow diffusion out of cells act to prolong antibiotic effects, thereby allowing for less frequent dosing. Our model can be used as a tool in the rational design of treatment for bacterial infections. It is easily adaptable to other biological systems, e.g. HIV, malaria and cancer, where the effects of physiological fluctuations of drug concentration are also poorly understood.

  1. Survey Strategy Optimization for the Atacama Cosmology Telescope

    De Bernardis, F.; Stevens, J. R.; Hasselfield, M.; Alonso, D.; Bond, J. R.; Calabrese, E.; Choi, S. K.; Crowley, K. T.; Devlin, M.; Wollack, E. J.

    2016-01-01

    In recent years there have been significant improvements in the sensitivity and the angular resolution of the instruments dedicated to the observation of the Cosmic Microwave Background (CMB). ACTPol is the first polarization receiver for the Atacama Cosmology Telescope (ACT) and is observing the CMB sky with arcmin resolution over approximately 2000 square degrees. Its upgrade, Advanced ACTPol (AdvACT), will observe the CMB in five frequency bands and over a larger area of the sky. We describe the optimization and implementation of the ACTPol and AdvACT surveys. The selection of the observed fields is driven mainly by the science goals, that is, small angular scale CMB measurements, B-mode measurements and cross-correlation studies. For the ACTPol survey we have observed patches of the southern galactic sky with low galactic foreground emissions which were also chosen to maximize the overlap with several galaxy surveys to allow unique cross-correlation studies. A wider field in the northern galactic cap ensured significant additional overlap with the BOSS spectroscopic survey. The exact shapes and footprints of the fields were optimized to achieve uniform coverage and to obtain cross-linked maps by observing the fields with different scan directions. We have maximized the efficiency of the survey by implementing a close to 24-hour observing strategy, switching between daytime and nighttime observing plans and minimizing the telescope idle time. We describe the challenges represented by the survey optimization for the significantly wider area observed by AdvACT, which will observe roughly half of the low-foreground sky. The survey strategies described here may prove useful for planning future ground-based CMB surveys, such as the Simons Observatory and CMB Stage IV surveys.

  2. [MPOWER--strategy for fighting the global tobacco epidemic].

    Kaleta, Dorota; Kozieł, Anna; Miśkiewicz, Paulina

    2009-01-01

    It is estimated that tobacco use may cause death of 5 million people in 2008, which is higher than the number of deaths attributed to tuberculosis (TB), HIV/AIDS and malaria taken together. By 2030, the number of deaths related to the tobacco epidemic could exceed annually even 8 million. Despite many difficulties, a growing number of countries undertake intensive actions aimed at tobacco control. The objective of this paper was to discuss the major objectives of the MPOWER Report issued by the World Health Organization (WHO). The MPOWER package consists a set of six key and most effective strategies for fighting the global tobacco epidemic: 1) Monitoring tobacco consumption and the effectiveness of preventive measures; 2) Protect people from tobacco smoke; 3) Offer help to quit tobacco use; 4) Warn about the dangers of tobacco; 5) Enforce bans on tobacco advertising, promotion and sponsorship; and 6) Raise taxes on tobacco. It is proven that these strategies implemented in the compatible way, effectively decreases tobacco use. In addition, MPOWER comprises epidemiological data, information on implemented tobacco control measures and their efficiency. MPOWER is the only one document of a somewhat strategic nature that is a source of information on the spread of tobacco epidemic, as well as of suggestions concerning specific actions for supporting the fight against this epidemic.

  3. Volcano monitoring using the Global Positioning System: Filtering strategies

    Larson, K.M.; Cervelli, Peter; Lisowski, M.; Miklius, Asta; Segall, P.; Owen, S.

    2001-01-01

    Permanent Global Positioning System (GPS) networks are routinely used for producing improved orbits and monitoring secular tectonic deformation. For these applications, data are transferred to an analysis center each day and routinely processed in 24-hour segments. To use GPS for monitoring volcanic events, which may last only a few hours, real-time or near real-time data processing and subdaily position estimates are valuable. Strategies have been researched for obtaining station coordinates every 15 min using a Kalman filter; these strategies have been tested on data collected by a GPS network on Kilauea Volcano. Data from this network are tracked continuously, recorded every 30 s, and telemetered hourly to the Hawaiian Volcano Observatory. A white noise model is heavily impacted by data outages and poor satellite geometry, but a properly constrained random walk model fits the data well. Using a borehole tiltmeter at Kilauea's summit as ground-truth, solutions using different random walk constraints were compared. This study indicates that signals on the order of 5 mm/h are resolvable using a random walk standard deviation of 0.45 cm/???h. Values lower than this suppress small signals, and values greater than this have significantly higher noise at periods of 1-6 hours. Copyright 2001 by the American Geophysical Union.

  4. Mobilization strategy to overcome global crisis of water consumption

    Suzdaleva, Antonina; Goryunova, Svetlana; Marchuk, Aleksey; Borovkov, Valery

    2017-10-01

    Today, the global water consumption crisis is one of the main threats that can disrupt socio-economic and environmental conditions of life of the majority of the world’s population. The water consumption mobilization strategy is based on the idea of increasing the available water resources. The main direction for the implementation of this strategy is the construction of anti-rivers - the systems for inter-basin (interregional) water resources redistribution. Antirivers are intended for controlled redistribution of water resources from regions with their catastrophic excess to regions with their critical shortage. The creation of anti-rivers, taking into account the requirements of environmental safety, will form large-scale managed natural- engineering systems and implement the principle of sustainable development adopted by the United Nations. The aim of the article is to substantiate a new methodological approach to address the problem, where the implementation of this approach can prevent large-scale humanitarian and environmental disasters expected in the coming years.

  5. Chinese Global and Russian Spatial Strategies: Harmonization Potential

    Pavel Aleksandrovich Minakir

    2017-06-01

    Full Text Available A probability of the harmonization of the Chinese sub-global strategy ‘One Belt, One Road’, proposed in 2013, and Russian integration project for the Eurasia economic cooperation are reviewed as well as the influence of this potential synchronized project on the Far Eastern segment of the Russian spatial strategy. It is noted that the problems of spatial heterogeneity gave push to the ‘One Belt, One Road’ project when China approached the point in economic development where different regional economic zones demand new infrastructural solutions for maintaining economic dynamics. The article shows that the declared co-development of countries involved is based on the rigid pragmatic financial-credit and infrastructural expansion of Central Asian model: mandatory provision of significant share in property (controlling stake, if possible, mandatory financing with construction contract and guaranteed future export of services for operating the facilities, ensuring the rights on full (or no less than 50% export of raw materials for further processing to China, employing Chinese labor in Russian-Chinese enterprises, and using Chinese machinery and equipment

  6. Identifying optimal agricultural countermeasure strategies for a hypothetical contamination scenario using the strategy model

    Cox, G.; Beresford, N.A.; Alvarez-Farizo, B.; Oughton, D.; Kis, Z.; Eged, K.; Thorring, H.; Hunt, J.; Wright, S.; Barnett, C.L.; Gil, J.M.; Howard, B.J.; Crout, N.M.J.

    2005-01-01

    A spatially implemented model designed to assist the identification of optimal countermeasure strategies for radioactively contaminated regions is described. Collective and individual ingestion doses for people within the affected area are estimated together with collective exported ingestion dose. A range of countermeasures are incorporated within the model, and environmental restrictions have been included as appropriate. The model evaluates the effectiveness of a given combination of countermeasures through a cost function which balances the benefit obtained through the reduction in dose with the cost of implementation. The optimal countermeasure strategy is the combination of individual countermeasures (and when and where they are implemented) which gives the lowest value of the cost function. The model outputs should not be considered as definitive solutions, rather as interactive inputs to the decision making process. As a demonstration the model has been applied to a hypothetical scenario in Cumbria (UK). This scenario considered a published nuclear power plant accident scenario with a total deposition of 1.7 x 10 14 , 1.2 x 10 13 , 2.8 x 10 10 and 5.3 x 10 9 Bq for Cs-137, Sr-90, Pu-239/240 and Am-241, respectively. The model predicts that if no remediation measures were implemented the resulting collective dose would be approximately 36 000 person-Sv (predominantly from 137 Cs) over a 10-year period post-deposition. The optimal countermeasure strategy is predicted to avert approximately 33 000 person-Sv at a cost of approximately pound 160 million. The optimal strategy comprises a mixture of ploughing, AFCF (ammonium-ferric hexacyano-ferrate) administration, potassium fertiliser application, clean feeding of livestock and food restrictions. The model recommends specific areas within the contaminated area and time periods where these measures should be implemented

  7. Global Optimization Employing Gaussian Process-Based Bayesian Surrogates

    Roland Preuss

    2018-03-01

    Full Text Available The simulation of complex physics models may lead to enormous computer running times. Since the simulations are expensive it is necessary to exploit the computational budget in the best possible manner. If for a few input parameter settings an output data set has been acquired, one could be interested in taking these data as a basis for finding an extremum and possibly an input parameter set for further computer simulations to determine it—a task which belongs to the realm of global optimization. Within the Bayesian framework we utilize Gaussian processes for the creation of a surrogate model function adjusted self-consistently via hyperparameters to represent the data. Although the probability distribution of the hyperparameters may be widely spread over phase space, we make the assumption that only the use of their expectation values is sufficient. While this shortcut facilitates a quickly accessible surrogate, it is somewhat justified by the fact that we are not interested in a full representation of the model by the surrogate but to reveal its maximum. To accomplish this the surrogate is fed to a utility function whose extremum determines the new parameter set for the next data point to obtain. Moreover, we propose to alternate between two utility functions—expected improvement and maximum variance—in order to avoid the drawbacks of each. Subsequent data points are drawn from the model function until the procedure either remains in the points found or the surrogate model does not change with the iteration. The procedure is applied to mock data in one and two dimensions in order to demonstrate proof of principle of the proposed approach.

  8. ASSESSMENT OF THE BUSINESS ENVIRONMENT FOR DEVELOPMENT OF GLOBAL MARKETING STRATEGY

    V. Savelyev

    2014-03-01

    Full Text Available The article concerns with essence of assessment of the business environment and specific directions of analysis during the working out of global marketing strategy. The classification of the global marketing environment researches and tasks sequence in the context of the decisions made on each stage of global marketing strategy is proposed.

  9. Landslide risk reduction strategies: an inventory for the Global South

    Maes, Jan; Kervyn, Matthieu; Vranken, Liesbet; Dewitte, Olivier; Vanmaercke, Matthias; Mertens, Kewan; Jacobs, Liesbet; Poesen, Jean

    2015-04-01

    Landslides constitute a serious problem globally. Moreover, landslide impact remains underestimated especially in the Global South. It is precisely there where the largest impact is experienced. An overview of measures taken to reduce risk of landslides in the Global South is however still lacking. Because in many countries of the Global South disaster risk reduction (DRR) is at an emerging stage, it is crucial to monitor the ongoing efforts (e.g. discussions on the Post-2015 Framework for DRR). The first objective of this study is to make an inventory of techniques and strategies that are applied to reduce risk from landslides in tropical countries. The second objective is to investigate what are the main bottlenecks for implementation of DRR strategies. In order to achieve these objectives, a review of both scientific and grey literature was conducted, supplemented with expert knowledge. The compilation of recommended and implemented DRR measures from landslide-prone tropical countries is based on an adapted classification proposed by the SafeLand project. According to Vaciago (2013), landslide risk can be reduced by either reducing the hazard, the vulnerability, the number or value of elements at risk or by sharing the residual risk. In addition, these measures can be combined with education and/or awareness raising and are influenced by governance structures and cultural beliefs. Global landslide datasets have been used to identify landslide-prone countries, augmented with region-specific datasets. Countries located in the tropics were selected in order to include landslide-prone countries with a different Human Development Index (HDI) but with a similar climate. Preliminary results support the statement made by Anderson (2013) that although the importance of shifting from post-disaster emergency actions to pre-disaster mitigation is acknowledged, in practice this paradigm shift seems rather limited. It is expected that this is especially the case in countries

  10. Robust approximate optimal guidance strategies for aeroassisted orbital transfer missions

    Ilgen, Marc R.

    This thesis presents the application of game theoretic and regular perturbation methods to the problem of determining robust approximate optimal guidance laws for aeroassisted orbital transfer missions with atmospheric density and navigated state uncertainties. The optimal guidance problem is reformulated as a differential game problem with the guidance law designer and Nature as opposing players. The resulting equations comprise the necessary conditions for the optimal closed loop guidance strategy in the presence of worst case parameter variations. While these equations are nonlinear and cannot be solved analytically, the presence of a small parameter in the equations of motion allows the method of regular perturbations to be used to solve the equations approximately. This thesis is divided into five parts. The first part introduces the class of problems to be considered and presents results of previous research. The second part then presents explicit semianalytical guidance law techniques for the aerodynamically dominated region of flight. These guidance techniques are applied to unconstrained and control constrained aeroassisted plane change missions and Mars aerocapture missions, all subject to significant atmospheric density variations. The third part presents a guidance technique for aeroassisted orbital transfer problems in the gravitationally dominated region of flight. Regular perturbations are used to design an implicit guidance technique similar to the second variation technique but that removes the need for numerically computing an optimal trajectory prior to flight. This methodology is then applied to a set of aeroassisted inclination change missions. In the fourth part, the explicit regular perturbation solution technique is extended to include the class of guidance laws with partial state information. This methodology is then applied to an aeroassisted plane change mission using inertial measurements and subject to uncertainties in the initial value

  11. Optimal strategy for selling on group-buying website

    Xuan Jiang

    2014-09-01

    Full Text Available Purpose: The purpose of this paper is to help business marketers with offline channels to make decisions on whether to sell through Group-buying (GB websites and how to set online price with the coordination of maximum deal size on GB websites. Design/methodology/approach: Considering the deal structure of GB websites especially for the service fee and minimum deal size limit required by GB websites, advertising effect of selling on GB websites, and interaction between online and offline markets, an analytical model is built to derive optimal online price and maximum deal size for sellers selling through GB website. This paper aims to answer four research questions: (1 How to make a decision on maximum deal size with coordination of the deal price? (2 Will selling on GB websites always be better than staying with offline channel only? (3 What kind of products is more appropriate to sell on GB website? (4How could GB website operator induce sellers to offer deep discount in GB deals? Findings and Originality/value: This paper obtains optimal strategies for sellers selling on GB website and finds that: Even if a seller has sufficient capacity, he/she may still set a maximum deal size on the GB deal to take advantage of Advertisement with Limited Availability (ALA effect; Selling through GB website may not bring a higher profit than selling only through offline channel when a GB site only has a small consumer base and/or if there is a big overlap between the online and offline markets; Low margin products are more suitable for being sold online with ALA strategies (LP-ALA or HP-ALA than high margin ones; A GB site operator could set a small minimum deal size to induce deep discounts from the sellers selling through GB deals. Research limitations/implications: The present study assumed that the demand function is determinate and linear. It will be interesting to study how stochastic demand and a more general demand function affect the optimal

  12. Global stability-based design optimization of truss structures using ...

    Furthermore, a pure pareto-ranking based multi-objective optimization model is employed for the design optimization of the truss structure with multiple objectives. The computational performance of the optimization model is increased by implementing an island model into its evolutionary search mechanism. The proposed ...

  13. An Improved Teaching-Learning-Based Optimization with the Social Character of PSO for Global Optimization

    Feng Zou

    2016-01-01

    Full Text Available An improved teaching-learning-based optimization with combining of the social character of PSO (TLBO-PSO, which is considering the teacher’s behavior influence on the students and the mean grade of the class, is proposed in the paper to find the global solutions of function optimization problems. In this method, the teacher phase of TLBO is modified; the new position of the individual is determined by the old position, the mean position, and the best position of current generation. The method overcomes disadvantage that the evolution of the original TLBO might stop when the mean position of students equals the position of the teacher. To decrease the computation cost of the algorithm, the process of removing the duplicate individual in original TLBO is not adopted in the improved algorithm. Moreover, the probability of local convergence of the improved method is decreased by the mutation operator. The effectiveness of the proposed method is tested on some benchmark functions, and the results are competitive with respect to some other methods.

  14. Public policy and risk financing strategies for global catastrophe risk management - the role of global risk initiatives

    McSharry, Patrick; Mitchell, Andrew; Anderson, Rebecca

    2010-05-01

    Decision-makers in both public and private organisations depend on accurate data and scientific understanding to adequately address climate change and the impact of extreme events. The financial impacts of catastrophes on populations and infrastructure can be offset through effective risk transfer mechanisms, structured to reflect the specific perils and levels of exposure to be covered. Optimal strategies depend on the likely socio-econonomic impact, the institutional framework, the overall objectives of the covers placed and the level of both the frequency and severity of loss potential expected. The diversity of approaches across different countries has been documented by the Spanish "Consorcio de Compensación de Seguros". We discuss why international public/private partnerships are necessary for addressing the risk of natural catastrophes. International initiatives such as the Global Earthquake Model (GEM) and the World Forum of Catastrophe Programmes (WFCP) can provide effective guidelines for constructing natural catastrophe schemes. The World Bank has been instrumental in the creation of many of the existing schemes such as the Turkish Catastrophe Insurance Pool, the Caribbean Catastrophe Risk Insurance Facility and the Mongolian Index-Based Livestock Insurance Program. We review existing schemes and report on best practice in relation to providing protection against natural catastrophe perils. The suitability of catastrophe modelling approaches to support schemes across the world are discussed and we identify opportunities to improve risk assessment for such schemes through transparent frameworks for quantifying, pricing, sharing and financing catastrophe risk on a local and global basis.

  15. A Simple But Effective Canonical Dual Theory Unified Algorithm for Global Optimization

    Zhang, Jiapu

    2011-01-01

    Numerical global optimization methods are often very time consuming and could not be applied for high-dimensional nonconvex/nonsmooth optimization problems. Due to the nonconvexity/nonsmoothness, directly solving the primal problems sometimes is very difficult. This paper presents a very simple but very effective canonical duality theory (CDT) unified global optimization algorithm. This algorithm has convergence is proved in this paper. More important, for this CDT-unified algorithm, numerous...

  16. A Strategy To Infuse a Global Perspective into Consumer Education.

    McGregor, Sue L. T.; Bourbonniere, Katherine

    2002-01-01

    A four-phase plan for delivering consumer education from a global perspective involves teachers in gaining familiarity with (1) the conventional approach to consumer education; (2) the cultures of globalization, capitalism, and consumerism; (3) the global perspective; and (4) integration of the three to create a global curriculum. (Contains 50…

  17. The deregulated global economy: women workers and strategies of resistance.

    Hale, A

    1996-10-01

    This article discusses the lack of input from women in international debates about the global economy. Women in the South are the most vulnerable to exploitation and most ignored in international discussions of how to protect fair labor standards. Restructuring has led to loss of secure jobs in the public sector and the expansion of female employment in low-paid, insecure, unskilled jobs. Businesses desire a cheap and flexible workforce. Declines in social services, the elimination of subsidies on basic goods, and the introduction of user fees puts pressure on women to supplement family income. A parallel outcome is reduced employment rights, neglect of health and safety standards, and increased disregard among women for their domestic responsibilities. There is a need for alternative models of development. The Self-Employed Women's Organization in India serves as a model for resisting exploitation among self-employed and home-based employees. Female industrial strikers are demanding attention to excessive hours of work, enforced overtime, bullying, and lack of sanitary and medical facilities. There is always fear that organized resistance will lead to industrial relocation or loss of jobs. The International Labor Organization has had a code for 20 years, but the threat of exposure to the press is sometimes more effective. There must be regulation throughout subcontracting chains of transnational companies. International alliances should revolve around issues/strategies identified by workers. International alliances are needed for influencing multinational companies and national governments and lobbying global economic and financial institutions. Standards that are included in social clause discussions are minimum requirements that do not address gender-specific issues. Women Working Worldwide is developing a position statement of social clauses that incorporates a women's perspective.

  18. An Overview of Optimizing Strategies for Flotation Banks

    Miguel Maldonado

    2012-10-01

    Full Text Available A flotation bank is a serial arrangement of cells. How to optimally operate a bank remains a challenge. This article reviews three reported strategies: air profiling, mass-pull (froth velocity profiling and Peak Air Recovery (PAR profiling. These are all ways of manipulating the recovery profile down a bank, which may be the property being exploited. Mathematical analysis has shown that a flat cell-by-cell recovery profile maximizes the separation of two floatable minerals for a given target bank recovery when the relative floatability is constant down the bank. Available bank survey data are analyzed with respect to recovery profiling. Possible variations on recovery profile to minimize entrainment are discussed.

  19. Gradient Material Strategies for Hydrogel Optimization in Tissue Engineering Applications

    2018-01-01

    Although a number of combinatorial/high-throughput approaches have been developed for biomaterial hydrogel optimization, a gradient sample approach is particularly well suited to identify hydrogel property thresholds that alter cellular behavior in response to interacting with the hydrogel due to reduced variation in material preparation and the ability to screen biological response over a range instead of discrete samples each containing only one condition. This review highlights recent work on cell–hydrogel interactions using a gradient material sample approach. Fabrication strategies for composition, material and mechanical property, and bioactive signaling gradient hydrogels that can be used to examine cell–hydrogel interactions will be discussed. The effects of gradients in hydrogel samples on cellular adhesion, migration, proliferation, and differentiation will then be examined, providing an assessment of the current state of the field and the potential of wider use of the gradient sample approach to accelerate our understanding of matrices on cellular behavior. PMID:29485612

  20. Optimizing urology group partnerships: collaboration strategies and compensation best practices.

    Jacoby, Dana L; Maller, Bruce S; Peltier, Lisa R

    2014-10-01

    Market forces in health care have created substantial regulatory, legislative, and reimbursement changes that have had a significant impact on urology group practices. To maintain viability, many urology groups have merged into larger integrated entities. Although group operations vary considerably, the majority of groups have struggled with the development of a strong culture, effective decision-making, and consensus-building around shared resources, income, and expense. Creating a sustainable business model requires urology group leaders to allocate appropriate time and resources to address these issues in a proactive manner. This article outlines collaboration strategies for creating an effective culture, governance, and leadership, and provides practical suggestions for optimizing the performance of the urology group practice.

  1. Optimal Strategies for Probing Terrestrial Exoplanet Atmospheres with JWST

    Batalha, Natasha E.; Lewis, Nikole K.; Line, Michael

    2018-01-01

    It is imperative that the exoplanet community determines the feasibility and the resources needed to yield high fidelity atmospheric compositions from terrestrial exoplanets. In particular, LHS 1140b and the TRAPPIST-1 system, already slated for observations by JWST’s Guaranteed Time Observers, will be the first two terrestrial planets observed by JWST. I will discuss optimal observing strategies for observing these two systems, focusing on the NIRSpec Prism (1-5μm) and the combination of NIRISS SOSS (1-2.7μm) and NIRSpec G395H (3-5μm). I will also introduce currently unsupported JWST readmodes that have the potential to greatly increase the precision on our atmospheric spectra. Lastly, I will use information content theory to compute the expected confidence interval on the retrieved abundances of key molecular species and temperature profiles as a function of JWST observing cycles.

  2. Optimized control strategy for crowbarless solid state modular power supply

    Upadhyay, R.; Badapanda, M.K.; Tripathi, A.; Hannurkar, P.R.; Pithawa, C.K.

    2009-01-01

    Solid state modular power supply with series connected IGBT based power modules have been employed as high voltage bias power supply of klystron amplifier. Auxiliary compensation of full wave inverter bridge with ZVS/ZCS operations of all IGBTs over entire operating range is incorporated. An optimized control strategy has been adopted for this power supply needing no output filter, making this scheme crowbarless and is presented in this paper. DSP based fully digital control with same duty cycle for all power modules, have been incorporated for regulating this power supply along with adequate protection features. Input to this power supply is taken directly from 11 kV line and the input system is intentionally made 24 pulsed to reduce the input harmonics, improve the input power factor significantly, there by requiring no line filters. Various steps have been taken to increase the efficiency of major subsystems, so as to improve the overall efficiency of this power supply significantly. (author)

  3. Evolution strategy based optimal chiller loading for saving energy

    Chang, Y.-C.; Lee, C.-Y.; Chen, C.-R.; Chou, C.-J.; Chen, W.-H.; Chen, W.-H.

    2009-01-01

    This study employs evolution strategy (ES) to solve optimal chiller loading (OCL) problem. ES overcomes the flaw that Lagrangian method is not adaptable for solving OCL as the power consumption models or the kW-PLR (partial load ratio) curves include convex functions and concave functions simultaneously. The complicated process of evolution by the genetic algorithm (GA) method for solving OCL can also be simplified by the ES method. This study uses the PLR of chiller as the variable to be solved for the decoupled air conditioning system. After analysis and comparison of the case study, it has been concluded that this method not only solves the problems of Lagrangian method and GA method, but also produces results with high accuracy within a rapid timeframe. It can be perfectly applied to the operation of air conditioning systems

  4. Optimal Inspection and Repair Strategies for Structural Systems

    Sommer, A. M.; Nowak, A. S.; Thoft-Christensen, Palle

    1992-01-01

    and a design variable as optimization variables. A model for estimating the total expected costs for structural systems is given including the costs associated with the loss of individual structural members as well as the costs associated with the loss of at least one element of a particular group......A model for reliability-based repair and maintenance strategies of structural systems is described. The total expected costs in the lifetime of the structure are minimized with the number of inspections, the number and positions of the inspected points, the inspection efforts, the repair criteria...... of structural members and the costs associated with the simultaneous loss of all members of a specific group of structural members. The approach is based on the pre-posteriori analysis from the classical decision theory. Special emphasis is given to the problem of selecting the number of points in the structure...

  5. Multi-slicing strategy for the three-dimensional discontinuity layout optimization (3D DLO).

    Zhang, Yiming

    2017-03-01

    Discontinuity layout optimization (DLO) is a recently presented topology optimization method for determining the critical layout of discontinuities and the associated upper bound limit load for plane two-dimensional and three-dimensional (3D) problems. The modelling process (pre-processing) for DLO includes defining the discontinuities inside a specified domain and building the target function and the global constraint matrix for the optimization solver, which has great influence on the the efficiency of the computation processes and the reliability of the final results. This paper focuses on efficient and reliable pre-processing of the discontinuities within the 3D DLO and presents a multi-slicing strategy, which naturally avoids the overlapping and crossing of different discontinuities. Furthermore, the formulation of the 3D discontinuity considering a shape of an arbitrary convex polygon is introduced, permitting the efficient assembly of the global constraint matrix. The proposed method eliminates unnecessary discontinuities in 3D DLO, making it possible to apply 3D DLO for solving large-scale engineering problems such as those involving landslides. Numerical examples including a footing test, a 3D landslide and a punch indentation are considered, illustrating the effectiveness of the presented method. © 2016 The Authors. International Journal for Numerical and Analytical Methods in Geomechanics published by John Wiley & Sons Ltd.

  6. Effective Energy Methods for Global Optimization for Biopolymer Structure Prediction

    Shalloway, David

    1998-01-01

    .... Its main strength is that it uncovers and exploits the intrinsic "hidden structures" of biopolymer energy landscapes to efficiently perform global minimization using a hierarchical search procedure...

  7. Residential CCHP microgrid with load aggregator: Operation mode, pricing strategy, and optimal dispatch

    Gu, Wei; Lu, Shuai; Wu, Zhi; Zhang, Xuesong; Zhou, Jinhui; Zhao, Bo; Wang, Jun

    2017-01-01

    Highlights: •A bilateral transaction mode for the residential CCHP microgrid is proposed. •An energy pricing strategy for the residential CCHP system is proposed. •A novel integrated demand response for the residential loads is proposed. •Two-stage operation optimization model for the CCHP microgrid is proposed. •Operations of typical days and annual scale of the CCHP microgrid are studied. -- Abstract: As the global energy crisis, environmental pollution, and global warming grow in intensity, increasing attention is being paid to combined cooling, heating, and power (CCHP) systems that realize high-efficiency cascade utilization of energy. This paper proposes a bilateral transaction mechanism between a residential CCHP system and a load aggregator (LA). The variable energy cost of the CCHP system is analyzed, based on which an energy pricing strategy for the CCHP system is proposed. Under this pricing strategy, the electricity price is constant, while the heat/cool price is ladder-shaped and dependent on the relationship between the electrical, heat, and cool loads. For the LA, an integrated demand response program is proposed that combines electricity-load shifting and a flexible heating/cooling supply, in which a thermodynamic model of buildings is used to determine the appropriate range of heating/cooling supply. Subsequently, a two-stage optimal dispatch model is proposed for the energy system that comprises the CCHP system and the LA. Case studies consisting of three scenarios (winter, summer, and excessive seasons) are delivered to demonstrate the effectiveness of the proposed approach, and the performance of the proposed pricing strategy is also evaluated by annual operation simulations.

  8. Globally optimal superconducting magnets part I: minimum stored energy (MSE) current density map.

    Tieng, Quang M; Vegh, Viktor; Brereton, Ian M

    2009-01-01

    An optimal current density map is crucial in magnet design to provide the initial values within search spaces in an optimization process for determining the final coil arrangement of the magnet. A strategy for obtaining globally optimal current density maps for the purpose of designing magnets with coaxial cylindrical coils in which the stored energy is minimized within a constrained domain is outlined. The current density maps obtained utilising the proposed method suggests that peak current densities occur around the perimeter of the magnet domain, where the adjacent peaks have alternating current directions for the most compact designs. As the dimensions of the domain are increased, the current density maps yield traditional magnet designs of positive current alone. These unique current density maps are obtained by minimizing the stored magnetic energy cost function and therefore suggest magnet coil designs of minimal system energy. Current density maps are provided for a number of different domain arrangements to illustrate the flexibility of the method and the quality of the achievable designs.

  9. Optimization of behavioral, biobehavioral, and biomedical interventions the multiphase optimization strategy (MOST)

    Collins, Linda M

    2018-01-01

    This book presents a framework for development, optimization, and evaluation of behavioral,  biobehavioral, and biomedical interventions.  Behavioral, biobehavioral, and biomedical interventions are programs with the objective of improving and maintaining human health and well-being, broadly defined, in individuals, families, schools, organizations, or communities.  These interventions may be aimed at, for example, preventing or treating disease, promoting physical and mental health, preventing violence, or improving academic achievement.   This volume introduces the Multiphase Optimization Strategy (MOST), pioneered at The Methodology Center at the Pennsylvania State University, as an alternative to the classical approach of relying solely on the randomized controlled trial (RCT).  MOST borrows heavily from perspectives taken and approaches used in engineering, and also integrates concepts from statistics and behavioral science, including the RCT.  As described in detail in this book, MOST consists of ...

  10. Optimal Order Strategy in Uncertain Demands with Free Shipping Option

    Qing-Chun Meng

    2014-01-01

    Full Text Available Free shipping with conditions has become one of the most effective marketing tools; more and more companies especially e-business companies prefer to offer free shipping to buyers whenever their orders exceed the minimum quantity specified by them. But in practice, the demands of buyers are uncertain, which are affected by weather, season, and many other factors. Firstly, we model the centralization ordering problem of retailers who face stochastic demands when suppliers offer free shipping, in which limited distributional information such as known mean, support, and some deviation measures of the random data is needed only. Then, based on the linear decision rule mainly for stochastic programming, we analyze the optimal order strategies of retailers and discuss the approximate solution. Further, we present the core allocation between all retailers via dual and cooperative game theory. The existence of core shows that each retailer is pleased to cooperate with others in the centralization problem. Finally, a numerical example is implemented to discuss how uncertain data and parameters affect the optimal solution.

  11. Optimizing the HLT Buffer Strategy with Monte Carlo Simulations

    AUTHOR|(CDS)2266763

    2017-01-01

    This project aims to optimize the strategy of utilizing the disk buffer for the High Level Trigger (HLT) of the LHCb experiment with the help of Monte-Carlo simulations. A method is developed, which simulates the Event Filter Farm (EFF) -- a computing cluster for the High Level Trigger -- as a compound of nodes with different performance properties. In this way, the behavior of the computing farm can be analyzed at a deeper level than before. It is demonstrated that the current operating strategy might be improved when data taking is reaching a mid-year scheduled stop or the year-end technical stop. The processing time of the buffered data can be lowered by distributing the detector data according to the processing power of the nodes instead of the relative disk size as long as the occupancy level of the buffer is low enough. Moreover, this ensures that data taken and stored on the buffer at the same time is processed by different nodes nearly simultaneously, which reduces load on the infrastructure.

  12. Quantifying global fossil-fuel CO2 emissions: from OCO-2 to optimal observing designs

    Ye, X.; Lauvaux, T.; Kort, E. A.; Oda, T.; Feng, S.; Lin, J. C.; Yang, E. G.; Wu, D.; Kuze, A.; Suto, H.; Eldering, A.

    2017-12-01

    Cities house more than half of the world's population and are responsible for more than 70% of the world anthropogenic CO2 emissions. Therefore, quantifications of emissions from major cities, which are only less than a hundred intense emitting spots across the globe, should allow us to monitor changes in global fossil-fuel CO2 emissions, in an independent, objective way. Satellite platforms provide favorable temporal and spatial coverage to collect urban CO2 data to quantify the anthropogenic contributions to the global carbon budget. We present here the optimal observation design for future NASA's OCO-2 and Japanese GOSAT missions, based on real-data (i.e. OCO-2) experiments and Observing System Simulation Experiments (OSSE's) to address different error components in the urban CO2 budget calculation. We identify the major sources of emission uncertainties for various types of cities with different ecosystems and geographical features, such as urban plumes over flat terrains, accumulated enhancements within basins, and complex weather regimes in coastal areas. Atmospheric transport errors were characterized under various meteorological conditions using the Weather Research and Forecasting (WRF) model at 1-km spatial resolution, coupled to the Open-source Data Inventory for Anthropogenic CO2 (ODIAC) emissions. We propose and discuss the optimized urban sampling strategies to address some difficulties from the seasonality in cloud cover and emissions, vegetation density in and around cities, and address the daytime sampling bias using prescribed diurnal cycles. These factors are combined in pseudo data experiments in which we evaluate the relative impact of uncertainties on inverse estimates of CO2 emissions for cities across latitudinal and climatological zones. We propose here several sampling strategies to minimize the uncertainties in target mode for tracking urban fossil-fuel CO2 emissions over the globe for future satellite missions, such as OCO-3 and future

  13. Elder Abuse: Global Situation, Risk Factors, and Prevention Strategies.

    Pillemer, Karl; Burnes, David; Riffin, Catherine; Lachs, Mark S

    2016-04-01

    Elder mistreatment is now recognized internationally as a pervasive and growing problem, urgently requiring the attention of health care systems, social welfare agencies, policymakers, and the general public. In this article, we provide an overview of global issues in the field of elder abuse, with a focus on prevention. This article provides a scoping review of key issues in the field from an international perspective. By drawing primarily on population-based studies, this scoping review provided a more valid and reliable synthesis of current knowledge about prevalence and risk factors than has been available. Despite the lack of scientifically rigorous intervention research on elder abuse, the review also identified 5 promising strategies for prevention. The findings highlight a growing consensus across studies regarding the extent and causes of elder mistreatment, as well as the urgent need for efforts to make elder mistreatment prevention programs more effective and evidence based. © The Author 2016. Published by Oxford University Press on behalf of The Gerontological Society of America. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  14. Overview of the status and global strategy for neonicotinoids.

    Jeschke, Peter; Nauen, Ralf; Schindler, Michael; Elbert, Alfred

    2011-04-13

    In recent years, neonicotinoid insecticides have been the fastest growing class of insecticides in modern crop protection, with widespread use against a broad spectrum of sucking and certain chewing pests. As potent agonists, they act selectively on insect nicotinic acetylcholine receptors (nAChRs), their molecular target site. The discovery of neonicotinoids can be considered as a milestone in insecticide research and greatly facilitates the understanding of functional properties of the insect nAChRs. In this context, the crystal structure of the acetylcholine-binding proteins provides the theoretical foundation for designing homology models of the corresponding receptor ligand binding domains within the nAChRs, a useful basis for virtual screening of chemical libraries and rational design of novel insecticides acting on these practically relevant channels. Because of the relatively low risk for nontarget organisms and the environment, the high target specificity of neonicotinoid insecticides, and their versatility in application methods, this important class has to be maintained globally for integrated pest management strategies and insect resistance management programs. Innovative concepts for life-cycle management, jointly with the introduction of generic products, have made neonicotinoids the most important chemical class for the insecticide market.

  15. Terrestrial Ecosystem Responses to Global Change: A Research Strategy

    Ecosystems Working Group,

    1998-09-23

    Uncertainty about the magnitude of global change effects on terrestrial ecosystems and consequent feedbacks to the atmosphere impedes sound policy planning at regional, national, and global scales. A strategy to reduce these uncertainties must include a substantial increase in funding for large-scale ecosystem experiments and a careful prioritization of research efforts. Prioritization criteria should be based on the magnitude of potential changes in environmental properties of concern to society, including productivity; biodiversity; the storage and cycling of carbon, water, and nutrients; and sensitivity of specific ecosystems to environmental change. A research strategy is proposed that builds on existing knowledge of ecosystem responses to global change by (1) expanding the spatial and temporal scale of experimental ecosystem manipulations to include processes known to occur at large scales and over long time periods; (2) quantifying poorly understood linkages among processes through the use of experiments that manipulate multiple interacting environmental factors over a broader range of relevant conditions than did past experiments; and (3) prioritizing ecosystems for major experimental manipulations on the basis of potential positive and negative impacts on ecosystem properties and processes of intrinsic and/or utilitarian value to humans and on feedbacks of terrestrial ecosystems to the atmosphere. Models and experiments are equally important for developing process-level understanding into a predictive capability. To support both the development and testing of mechanistic ecosystem models, a two-tiered design of ecosystem experiments should be used. This design should include both (1) large-scale manipulative experiments for comprehensive testing of integrated ecosystem models and (2) multifactor, multilevel experiments for parameterization of process models across the critical range of interacting environmental factors (CO{sub 2}, temperature, water

  16. Order-Constrained Solutions in K-Means Clustering: Even Better than Being Globally Optimal

    Steinley, Douglas; Hubert, Lawrence

    2008-01-01

    This paper proposes an order-constrained K-means cluster analysis strategy, and implements that strategy through an auxiliary quadratic assignment optimization heuristic that identifies an initial object order. A subsequent dynamic programming recursion is applied to optimally subdivide the object set subject to the order constraint. We show that…

  17. An Evaluation of the Sniffer Global Optimization Algorithm Using Standard Test Functions

    Butler, Roger A. R.; Slaminka, Edward E.

    1992-03-01

    The performance of Sniffer—a new global optimization algorithm—is compared with that of Simulated Annealing. Using the number of function evaluations as a measure of efficiency, the new algorithm is shown to be significantly better at finding the global minimum of seven standard test functions. Several of the test functions used have many local minima and very steep walls surrounding the global minimum. Such functions are intended to thwart global minimization algorithms.

  18. Global History. A Curriculum Guide. Second Semester. Theme V: The Industrial Revolution Had Global Impact. Teacher Strategies. Experimental Edition.

    New York City Board of Education, Brooklyn, NY. Div. of Curriculum and Instruction.

    Designed to assist teachers and supervisors in the implementation of the global history course, this bulletin presents learning activities which include the rationale, performance objectives, and teaching strategies related to Theme V entitled, "The Industrial Revolution Had Global Impact." This theme has seven subthemes: (1)…

  19. Optimization of refueling-shuffling scheme in PWR core by random search strategy

    Wu Yuan

    1991-11-01

    A random method for simulating optimization of refueling management in a pressurized water reactor (PWR) core is described. The main purpose of the optimization was to select the 'best' refueling arrangement scheme which would produce maximum economic benefits under certain imposed conditions. To fulfill this goal, an effective optimization strategy, two-stage random search method was developed. First, the search was made in a manner similar to the stratified sampling technique. A local optimum can be reached by comparison of the successive results. Then the other random experiences would be carried on between different strata to try to find the global optimum. In general, it can be used as a practical tool for conventional fuel management scheme. However, it can also be used in studies on optimization of Low-Leakage fuel management. Some calculations were done for a typical PWR core on a CYBER-180/830 computer. The results show that the method proposed can obtain satisfactory approach at reasonable low computational cost

  20. Group search optimiser-based optimal bidding strategies with no Karush-Kuhn-Tucker optimality conditions

    Yadav, Naresh Kumar; Kumar, Mukesh; Gupta, S. K.

    2017-03-01

    General strategic bidding procedure has been formulated in the literature as a bi-level searching problem, in which the offer curve tends to minimise the market clearing function and to maximise the profit. Computationally, this is complex and hence, the researchers have adopted Karush-Kuhn-Tucker (KKT) optimality conditions to transform the model into a single-level maximisation problem. However, the profit maximisation problem with KKT optimality conditions poses great challenge to the classical optimisation algorithms. The problem has become more complex after the inclusion of transmission constraints. This paper simplifies the profit maximisation problem as a minimisation function, in which the transmission constraints, the operating limits and the ISO market clearing functions are considered with no KKT optimality conditions. The derived function is solved using group search optimiser (GSO), a robust population-based optimisation algorithm. Experimental investigation is carried out on IEEE 14 as well as IEEE 30 bus systems and the performance is compared against differential evolution-based strategic bidding, genetic algorithm-based strategic bidding and particle swarm optimisation-based strategic bidding methods. The simulation results demonstrate that the obtained profit maximisation through GSO-based bidding strategies is higher than the other three methods.

  1. Decision support model for establishing the optimal energy retrofit strategy for existing multi-family housing complexes

    Hong, Taehoon; Koo, Choongwan; Kim, Hyunjoong; Seon Park, Hyo

    2014-01-01

    The number of multi-family housing complexes (MFHCs) over 15 yr old in South Korea is expected to exceed 5 million by 2015. Accordingly, the demand for energy retrofit in the deteriorating MFHCs is rapidly increasing. This study aimed to develop a decision support model for establishing the optimal energy retrofit strategy for existing MFHCs. It can provide clear criteria for establishing the carbon emissions reduction target (CERT) and allow efficient budget allocation for conducting the energy retrofit. The CERT for “S” MFHC, one of MFHCs located in Seoul, as a case study, was set at 23.0% (electricity) and 27.9% (gas energy). In the economic and environmental assessment, it was determined that scenario #12 was the optimal scenario (ranked second with regard to NPV 40 (net present value at year 40) and third with regard to SIR 40 (saving to investment ratio at year 40). The proposed model could be useful for owners, construction managers, or policymakers in charge of establishing energy retrofit strategy for existing MFHCs. It could allow contractors in a competitive bidding process to rationally establish the CERT and select the optimal energy retrofit strategy. It can be also applied to any other country or sector in a global environment. - Highlights: • The proposed model was developed to establish the optimal energy retrofit strategy. • Advanced case-based reasoning was applied to establish the community-based CERT. • Energy simulation was conducted to analyze the effects of energy retrofit strategy. • The optimal strategy can be finally selected based on the LCC and LCCO 2 analysis. • It could be extended to any other country or sector in the global environment

  2. Exploring the Optimal Strategy to Predict Essential Genes in Microbes

    Yao Lu

    2011-12-01

    Full Text Available Accurately predicting essential genes is important in many aspects of biology, medicine and bioengineering. In previous research, we have developed a machine learning based integrative algorithm to predict essential genes in bacterial species. This algorithm lends itself to two approaches for predicting essential genes: learning the traits from known essential genes in the target organism, or transferring essential gene annotations from a closely related model organism. However, for an understudied microbe, each approach has its potential limitations. The first is constricted by the often small number of known essential genes. The second is limited by the availability of model organisms and by evolutionary distance. In this study, we aim to determine the optimal strategy for predicting essential genes by examining four microbes with well-characterized essential genes. Our results suggest that, unless the known essential genes are few, learning from the known essential genes in the target organism usually outperforms transferring essential gene annotations from a related model organism. In fact, the required number of known essential genes is surprisingly small to make accurate predictions. In prokaryotes, when the number of known essential genes is greater than 2% of total genes, this approach already comes close to its optimal performance. In eukaryotes, achieving the same best performance requires over 4% of total genes, reflecting the increased complexity of eukaryotic organisms. Combining the two approaches resulted in an increased performance when the known essential genes are few. Our investigation thus provides key information on accurately predicting essential genes and will greatly facilitate annotations of microbial genomes.

  3. Global optimization for overall HVAC systems - Part I problem formulation and analysis

    Lu Lu; Cai Wenjian; Chai, Y.S.; Xie Lihua

    2005-01-01

    This paper presents the global optimization technologies for overall heating, ventilating and air conditioning (HVAC) systems. The objective function of global optimization and constraints are formulated based on mathematical models of the major components. All these models are associated with power consumption components and heat exchangers for transferring cooling load. The characteristics of all the major components are briefly introduced by models, and the interactions between them are analyzed and discussed to show the complications of the problem. According to the characteristics of the operating components, the complicated original optimization problem for overall HVAC systems is transformed and simplified into a compact form ready for optimization

  4. Optimizing strategies to improve interprofessional practice for veterans, part 1

    Bhattacharya SB

    2014-04-01

    Full Text Available Shelley B Bhattacharya,1–3 Michelle I Rossi,1,2 Jennifer M Mentz11Geriatric Research Education and Clinical Center (GRECC, Veteran's Affairs Pittsburgh Healthcare System, 2University of Pittsburgh Medical Center, Pittsburgh, PA, USA; 3Albert Schweitzer Fellowship Program, Pittsburgh, PA, USAIntroduction: Interprofessional patient care is a well-recognized path that health care systems are striving toward. The Veteran's Affairs (VA system initiated interprofessional practice (IPP models with their Geriatric Evaluation and Management (GEM programs. GEM programs incorporate a range of specialties, including but not limited to, medicine, nursing, social work, physical therapy and pharmacy, to collaboratively evaluate veterans. Despite being a valuable resource, they are now faced with significant cut-backs, including closures. The primary goal of this project was to assess how the GEM model could be optimized at the Pittsburgh, Pennsylvania VA to allow for the sustainability of this important IPP assessment. Part 1 of the study evaluated the IPP process using program, patient, and family surveys. Part 2 examined how well the geriatrician matched patients to specialists in the GEM model. This paper describes Part 1 of our study.Methods: Three strategies were used: 1 a national GEM program survey; 2 a veteran/family satisfaction survey; and 3 an absentee assessment.Results: Twenty-six of 92 programs responded to the GEM IPP survey. Six strategies were shared to optimize IPP models throughout the country. Of the 34 satisfaction surveys, 80% stated the GEM clinic was beneficial, 79% stated their concerns were addressed, and 100% would recommend GEM to their friends. Of the 24 absentee assessments, the top three reasons for missing the appointments were transportation, medical illnesses, and not knowing/remembering about the appointment. Absentee rate diminished from 41% to 19% after instituting a reminder phone call policy.Discussion: Maintaining the

  5. Emergency strategy optimization for the environmental control system in manned spacecraft

    Li, Guoxiang; Pang, Liping; Liu, Meng; Fang, Yufeng; Zhang, Helin

    2018-02-01

    It is very important for a manned environmental control system (ECS) to be able to reconfigure its operation strategy in emergency conditions. In this article, a multi-objective optimization is established to design the optimal emergency strategy for an ECS in an insufficient power supply condition. The maximum ECS lifetime and the minimum power consumption are chosen as the optimization objectives. Some adjustable key variables are chosen as the optimization variables, which finally represent the reconfigured emergency strategy. The non-dominated sorting genetic algorithm-II is adopted to solve this multi-objective optimization problem. Optimization processes are conducted at four different carbon dioxide partial pressure control levels. The study results show that the Pareto-optimal frontiers obtained from this multi-objective optimization can represent the relationship between the lifetime and the power consumption of the ECS. Hence, the preferred emergency operation strategy can be recommended for situations when there is suddenly insufficient power.

  6. Optimal Portfolios in Wishart Models and Effects of Discrete Rebalancing on Portfolio Distribution and Strategy Selection

    Li, Zejing

    2012-01-01

    This dissertation is mainly devoted to the research of two problems - the continuous-time portfolio optimization in different Wishart models and the effects of discrete rebalancing on portfolio wealth distribution and optimal portfolio strategy.

  7. Verification and synthesis of optimal decision strategies for complex systems

    Summers, S. J.

    2013-07-01

    that quantifies the probability of hitting a target set at some point during a finite time horizon, while avoiding an obstacle set during each time step preceding the target hitting time. In contrast with the general reach-avoid formulation, which assumes that the target and obstacle sets are constant and deterministic, we allow these sets to be both time-varying and probabilistic. An optimal reach-avoid control policy is derived as the solution to an optimal control problem via dynamic programming. A framework for analyzing probabilistic safety and reachability problems for discrete time stochastic hybrid systems in scenarios where system dynamics are affected by rational competing agents follows. We consider a zero sum game formulation of the probabilistic reach-avoid problem, in which the control objective is to maximize the probability of reaching a desired subset of the hybrid state space, while avoiding an unsafe set, subject to the worst case behavior of a rational adversary. Theoretical results are provided on a dynamic programming algorithm for computing the maximal reach-avoid probability under the worst-case adversary strategy, as well as the existence of a maxmin control policy that achieves this probability. Probabilistic Computation Tree Logic (PCTL) is a well-known modal logic that has become a standard for expressing temporal properties of finite state Markov chains in the context of automated model checking. Here we consider PCTL for non countable-space Markov chains, and we show that there is a substantial affinity between certain of its operators and problems of dynamic programming. We prove some basic properties of the solutions to the latter. The dissertation concludes with a collection of computational examples in the areas of ecology, robotics, aerospace, and finance. (author)

  8. Verification and synthesis of optimal decision strategies for complex systems

    Summers, S. J.

    2013-01-01

    that quantifies the probability of hitting a target set at some point during a finite time horizon, while avoiding an obstacle set during each time step preceding the target hitting time. In contrast with the general reach-avoid formulation, which assumes that the target and obstacle sets are constant and deterministic, we allow these sets to be both time-varying and probabilistic. An optimal reach-avoid control policy is derived as the solution to an optimal control problem via dynamic programming. A framework for analyzing probabilistic safety and reachability problems for discrete time stochastic hybrid systems in scenarios where system dynamics are affected by rational competing agents follows. We consider a zero sum game formulation of the probabilistic reach-avoid problem, in which the control objective is to maximize the probability of reaching a desired subset of the hybrid state space, while avoiding an unsafe set, subject to the worst case behavior of a rational adversary. Theoretical results are provided on a dynamic programming algorithm for computing the maximal reach-avoid probability under the worst-case adversary strategy, as well as the existence of a maxmin control policy that achieves this probability. Probabilistic Computation Tree Logic (PCTL) is a well-known modal logic that has become a standard for expressing temporal properties of finite state Markov chains in the context of automated model checking. Here we consider PCTL for non countable-space Markov chains, and we show that there is a substantial affinity between certain of its operators and problems of dynamic programming. We prove some basic properties of the solutions to the latter. The dissertation concludes with a collection of computational examples in the areas of ecology, robotics, aerospace, and finance. (author)

  9. Computing Optimal Stochastic Portfolio Execution Strategies: A Parametric Approach Using Simulations

    Moazeni, Somayeh; Coleman, Thomas F.; Li, Yuying

    2010-09-01

    Computing optimal stochastic portfolio execution strategies under appropriate risk consideration presents great computational challenge. We investigate a parametric approach for computing optimal stochastic strategies using Monte Carlo simulations. This approach allows reduction in computational complexity by computing coefficients for a parametric representation of a stochastic dynamic strategy based on static optimization. Using this technique, constraints can be similarly handled using appropriate penalty functions. We illustrate the proposed approach to minimize the expected execution cost and Conditional Value-at-Risk (CVaR).

  10. Optimal Stochastic Advertising Strategies for the U.S. Beef Industry

    Kun C. Lee; Stanley Schraufnagel; Earl O. Heady

    1982-01-01

    An important decision variable in the promotional strategy for the beef sector is the optimal level of advertising expenditures over time. Optimal stochastic and deterministic advertising expenditures are derived for the U.S. beef industry for the period `1966 through 1980. They are compared with historical levels and gains realized by optimal advertising strategies are measured. Finally, the optimal advertising expenditures in the future are forecasted.

  11. A branch and bound algorithm for the global optimization of Hessian Lipschitz continuous functions

    Fowkes, Jaroslav M.; Gould, Nicholas I. M.; Farmer, Chris L.

    2012-01-01

    We present a branch and bound algorithm for the global optimization of a twice differentiable nonconvex objective function with a Lipschitz continuous Hessian over a compact, convex set. The algorithm is based on applying cubic regularisation

  12. Global optimization of maintenance and surveillance testing based on reliability and probabilistic safety assessment. Research project

    Martorell, S.; Serradell, V.; Munoz, A.; Sanchez, A.

    1997-01-01

    Background, objective, scope, detailed working plan and follow-up and final product of the project ''Global optimization of maintenance and surveillance testing based on reliability and probabilistic safety assessment'' are described

  13. An optimization strategy for the control of small capacity heat pump integrated air-conditioning system

    Gao, Jiajia; Huang, Gongsheng; Xu, Xinhua

    2016-01-01

    Highlights: • An optimization strategy for a small-scale air-conditioning system is developed. • The optimization strategy aims at optimizing the overall system energy consumption. • The strategy may guarantee the robust control of the space air temperature. • The performance of the optimization strategy was tested on a simulation platform. - Abstract: This paper studies the optimization of a small-scale central air-conditioning system, in which the cooling is provided by a ground source heat pump (GSHP) equipped with an on/off capacity control. The optimization strategy aims to optimize the overall system energy consumption and simultaneously guarantee the robustness of the space air temperature control without violating the allowed GSHP maximum start-ups number per hour specified by customers. The set-point of the chilled water return temperature and the width of the water temperature control band are used as the decision variables for the optimization. The performance of the proposed strategy was tested on a simulation platform. Results show that the optimization strategy can save the energy consumption by 9.59% in a typical spring day and 2.97% in a typical summer day. Meanwhile it is able to enhance the space air temperature control robustness when compared with a basic control strategy without optimization.

  14. Forest Service Global Change Research Strategy, 2009-2019 Implementation Plan

    Allen Solomon; Richard A. Birdsey; Linda A. Joyce

    2010-01-01

    In keeping with the research goals of the U.S. Global Change Research Program, the climate change strategy of the U.S. Department of Agriculture (USDA), and the climate change framework of the Forest Service, this Forest Service Global Change Research Strategy, 2009-2019 Implementation Plan (hereafter called the Research Plan), was written by Forest Service Research...

  15. Global Strategy: The World is your Oyster (if you can shuck it!)

    T.H. Reus (Taco)

    2014-01-01

    textabstractIn this inaugural lecture, Taco briefly describes the disciplinary background, central research questions, and themes of Global Strategy, and he presents what may be the dominant framework of understanding how global strategy works and what determines its success. In a nutshell, the

  16. Noninfectious uveitis: strategies to optimize treatment compliance and adherence

    Dolz-Marco R

    2015-08-01

    Full Text Available Rosa Dolz-Marco,1 Roberto Gallego-Pinazo,1 Manuel Díaz-Llopis,2 Emmett T Cunningham Jr,3–6 J Fernando Arévalo7,8 1Unit of Macula, Department of Ophthalmology, University and Polytechnic Hospital La Fe, 2Faculty of Medicine, University of Valencia, Spain; 3Department of Ophthalmology, California Pacific Medical Center, San Francisco, 4Department of Ophthalmology, Stanford University School of Medicine, Stanford, 5The Francis I Proctor Foundation, University of California San Francisco Medical Center, 6West Coast Retina Medical Group, San Francisco, CA, USA; 7Vitreoretina Division, King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia; 8Retina Division, Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA Abstract: Noninfectious uveitis includes a heterogenous group of sight-threatening ocular and systemic disorders. Significant progress has been made in the treatment of noninfectious uveitis in recent years, particularly with regard to the effective use of corticosteroids and non-corticosteroid immunosuppressive drugs, including biologic agents. All of these therapeutic approaches are limited, however, by any given patient’s ability to comply with and adhere to their prescribed treatment. In fact, compliance and adherence are among the most important patient-related determinants of treatment success. We discuss strategies to optimize compliance and adherence. Keywords: noninfectious uveitis, intraocular inflammation, immunosuppressive treatment, adherence, compliance, therapeutic failure

  17. Optimal breast cancer screening strategies for older women: current perspectives

    Braithwaite D

    2016-02-01

    Full Text Available Dejana Braithwaite,1 Joshua Demb,1 Louise M Henderson2 1Department of Epidemiology and Biostatistics, University of California, San Francisco, CA, 2Department of Radiology, University of North Carolina, Chapel Hill, NC, USA Abstract: Breast cancer is a major cause of cancer-related deaths among older women, aged 65 years or older. Screening mammography has been shown to be effective in reducing breast cancer mortality in women aged 50–74 years but not among those aged 75 years or older. Given the large heterogeneity in comorbidity status and life expectancy among older women, controversy remains over screening mammography in this population. Diminished life expectancy with aging may decrease the potential screening benefit and increase the risk of harms. In this review, we summarize the evidence on screening mammography utilization, performance, and outcomes and highlight evidence gaps. Optimizing the screening strategy will involve separating older women who will benefit from screening from those who will not benefit by using information on comorbidity status and life expectancy. This review has identified areas related to screening mammography in older women that warrant additional research, including the need to evaluate emerging screening technologies, such as tomosynthesis among older women and precision cancer screening. In the absence of randomized controlled trials, the benefits and harms of continued screening mammography in older women need to be estimated using both population-based cohort data and simulation models. Keywords: aging, breast cancer, precision cancer screening

  18. An Optimal Investment Strategy for Insurers in Incomplete Markets

    Mohamed Badaoui

    2018-04-01

    Full Text Available In this paper we consider the problem of an insurance company where the wealth of the insurer is described by a Cramér-Lundberg process. The insurer is allowed to invest in a risky asset with stochastic volatility subject to the influence of an economic factor and the remaining surplus in a bank account. The price of the risky asset and the economic factor are modeled by a system of correlated stochastic differential equations. In a finite horizon framework and assuming that the market is incomplete, we study the problem of maximizing the expected utility of terminal wealth. When the insurer’s preferences are exponential, an existence and uniqueness theorem is proven for the non-linear Hamilton-Jacobi-Bellman equation (HJB. The optimal strategy and the value function have been produced in closed form. In addition and in order to show the connection between the insurer’s decision and the correlation coefficient we present two numerical approaches: A Monte-Carlo method based on the stochastic representation of the solution of the insurer problem via Feynman-Kac’s formula, and a mixed Finite Difference Monte-Carlo one. Finally the results are presented in the case of Scott model.

  19. Optimizing individual iron deficiency prevention strategies in physiological pregnancy

    Kramarskiy V.A.

    2018-04-01

    Full Text Available Sideropenia by the end of pregnancy takes place in all mothers without exception. Moreover, the selective administration of iron preparations, in contrast to the routine, makes it possible to avoid hemochromatosis, frequency of which in the general population makes from 0.5 to 13 %. The aim of the study was to optimize the individual strategy for the prevention of iron deficiency in physiological pregnancy. A prospective pre-experimental study was conducted, the criterion of inclusion in which was the mother’s extragenital and obstetrical pathology during the first half of pregnancy, a burdened obstetric and gynecological anamnesis. The study group of 98 women with a physiological pregnancy in the period of 20 to 24 weeks was recruited by simple ran- dom selection. Serum ferritin, hemoglobin, and serum iron were used to estimate iron deficiency. In the latent stage of iron deficiency against a background of monthly correction with Fenules ® in a dose of 90 mg of elemental iron per day, there was a significant increase in ferritin and iron in the blood rotor. In healthy mothers, during the gestational period of 20–24 weeks, a regularity arises in the replenishment of iron status, especially in the case of repeated pregnancy, which is successfully satisfied during the month of Fenules ® intake in doses of 45 mg or 90 mg per day with a serum ferritin level of, respectively, 30 up to 70 μg/l or less than 30 μg/l.

  20. Global Networks: Emerging Constraints on Strategy (Defense Horizons, July 2004)

    Fonow, Bob

    2004-01-01

    .... This shift is problematic for U.S. national security, because the global telecommunications infrastructure is becoming an important strategic battlespace the physical battlefield of information warfare...

  1. Global blending optimization of laminated composites with discrete material candidate selection and thickness variation

    Sørensen, Søren N.; Stolpe, Mathias

    2015-01-01

    rate. The capabilities of the method and the effect of active versus inactive manufacturing constraints are demonstrated on several numerical examples of limited size, involving at most 320 binary variables. Most examples are solved to guaranteed global optimality and may constitute benchmark examples...... but is, however, convex in the original mixed binary nested form. Convexity is the foremost important property of optimization problems, and the proposed method can guarantee the global or near-global optimal solution; unlike most topology optimization methods. The material selection is limited...... for popular topology optimization methods and heuristics based on solving sequences of non-convex problems. The results will among others demonstrate that the difficulty of the posed problem is highly dependent upon the composition of the constitutive properties of the material candidates....

  2. Globally Optimal Segmentation of Permanent-Magnet Systems

    Insinga, Andrea Roberto; Bjørk, Rasmus; Smith, Anders

    2016-01-01

    Permanent-magnet systems are widely used for generation of magnetic fields with specific properties. The reciprocity theorem, an energy-equivalence principle in magnetostatics, can be employed to calculate the optimal remanent flux density of the permanent-magnet system, given any objective...... remains unsolved. We show that the problem of optimal segmentation of a two-dimensional permanent-magnet assembly with respect to a linear objective functional can be reduced to the problem of piecewise linear approximation of a plane curve by perimeter maximization. Once the problem has been cast...

  3. The Tunneling Method for Global Optimization in Multidimensional Scaling.

    Groenen, Patrick J. F.; Heiser, Willem J.

    1996-01-01

    A tunneling method for global minimization in multidimensional scaling is introduced and adjusted for multidimensional scaling with general Minkowski distances. The method alternates a local search step with a tunneling step in which a different configuration is sought with the same STRESS implementation. (SLD)

  4. Global Optimization of a Periodic System using a Genetic Algorithm

    Stucke, David; Crespi, Vincent

    2001-03-01

    We use a novel application of a genetic algorithm global optimizatin technique to find the lowest energy structures for periodic systems. We apply this technique to colloidal crystals for several different stoichiometries of binary and trinary colloidal crystals. This application of a genetic algorithm is decribed and results of likely candidate structures are presented.

  5. Developing Strategies for Islamic Banks to Face the Future Challenges of Financial Globalization

    Al Ajlouni, Ahmed

    2004-01-01

    Developing Strategies for Islamic Banks to Face the Future Challenges of Financial Globalization Ahmed Al-Ajlouni Abstract This study aims at forming strategic response to assess the ability of Islamic banks in benefiting from the opportunities that may be provided by financial globalization and limits its threats, through assessing the capability of Islamic banks to meet the requirements and challenges of financial globalization, then suggests the suitable strategies that may be ...

  6. Global Launcher Trajectory Optimization for Lunar Base Settlement

    Pagano, A.; Mooij, E.

    2010-01-01

    The problem of a mission to the Moon to set a permanent outpost can be tackled by dividing the journey into three phases: the Earth ascent, the Earth-Moon transfer and the lunar landing. In this paper we present an optimization analysis of Earth ascent trajectories of existing launch vehicles

  7. Vertical bifacial solar farms: Physics, design, and global optimization

    Khan, M. Ryyan; Hanna, Amir; Sun, Xingshu; Alam, Muhammad A.

    2017-01-01

    10–20% more energy than a traditional monofacial farm for a practical row-spacing of 2 m (corresponding to 1.2 m high panels). With the prospect of additional 5–20% energy gain from reduced soiling and tilt optimization, bifacial solar farm do offer a

  8. Global stability-based design optimization of truss structures using ...

    The quality of current pareto front obtained in the end of a whole genetic search is assessed according to its closeness to the ...... better optimal designation with a lower displacement value of 0.3075 in. satisfying the service- .... Internal force. R.

  9. Connecting strategy and execution in global R&D

    Sbernini, Federico; Granini, Nicola; Herbert-Hansen, Zaza Nadja Lee

    2017-01-01

    The paper investigates the relationship between global product development strategic decisions, which include outsourcing, offshoring practices as well as strategic alliances, and their impact on the day-to-day business in a global and open innovation context. By adopting an exploratory inductive...

  10. China's Coal Methane: Actors, Structures, Strategies and their Global Impacts

    Chen, Ke; Charnoz, Olivier

    2012-12-01

    The need for China to alleviate its energy shortage, reduce its dependence on foreign sources and mitigate its climate impact is driving a dire quest for alternative fuels. Coal Mine Methane (CMM), in this context, holds significant potential. While the 11. Five-Year Plan aimed to capture and use 10 billion m"3 per year of CMM by 2010, the country achieved less than a quarter of this. This paper enquires into this puzzling outcome, which bears consequences for the world at large. China is indeed responsible for more than 40% of the world's total un-captured CMM emissions - which act as a greenhouse gas 21 times more potent than CO_2, and whose role in global warming is often underestimated, especially in short- and medium-term climate strategies. While the Chinese central government may have incentive to work towards promoting CMM, the benefits of such policies at the sub-national level are far from self-evident. National CMM policies can have significant economic and social costs at the local level, and thus their implementation can be jeopardized. Implementation of such policies is inherently ambiguous, conflicting, and as such, political. Current research on the Chinese CMM industry has largely focused on its techno-economic aspects, with little if any politico-institutional analyses. As for policy research on the larger Chinese energy sector, this seems sturdily to embody a top-down view: it mostly ends up blaming the country's decentralized governance structure and lack of a stringent implementation chain. Such top-down approaches do not help uncover 'the sinews of war': the range of less formal mechanisms, negotiations and agreements among the local actors, without which implementation does not in fact occur at the sub-national level. Nor do top-down research approaches facilitate inquiry into the way local stakeholders re-frame the meaning, content and impact of CMM policies. More generally, the top-down approaches fail to consider the significance of

  11. Polymerase chain reaction: basic protocol plus troubleshooting and optimization strategies.

    Lorenz, Todd C

    2012-05-22

    In the biological sciences there have been technological advances that catapult the discipline into golden ages of discovery. For example, the field of microbiology was transformed with the advent of Anton van Leeuwenhoek's microscope, which allowed scientists to visualize prokaryotes for the first time. The development of the polymerase chain reaction (PCR) is one of those innovations that changed the course of molecular science with its impact spanning countless subdisciplines in biology. The theoretical process was outlined by Keppe and coworkers in 1971; however, it was another 14 years until the complete PCR procedure was described and experimentally applied by Kary Mullis while at Cetus Corporation in 1985. Automation and refinement of this technique progressed with the introduction of a thermal stable DNA polymerase from the bacterium Thermus aquaticus, consequently the name Taq DNA polymerase. PCR is a powerful amplification technique that can generate an ample supply of a specific segment of DNA (i.e., an amplicon) from only a small amount of starting material (i.e., DNA template or target sequence). While straightforward and generally trouble-free, there are pitfalls that complicate the reaction producing spurious results. When PCR fails it can lead to many non-specific DNA products of varying sizes that appear as a ladder or smear of bands on agarose gels. Sometimes no products form at all. Another potential problem occurs when mutations are unintentionally introduced in the amplicons, resulting in a heterogeneous population of PCR products. PCR failures can become frustrating unless patience and careful troubleshooting are employed to sort out and solve the problem(s). This protocol outlines the basic principles of PCR, provides a methodology that will result in amplification of most target sequences, and presents strategies for optimizing a reaction. By following this PCR guide, students should be able to: • Set up reactions and thermal cycling

  12. Global WASF-GA: An Evolutionary Algorithm in Multiobjective Optimization to Approximate the Whole Pareto Optimal Front.

    Saborido, Rubén; Ruiz, Ana B; Luque, Mariano

    2017-01-01

    In this article, we propose a new evolutionary algorithm for multiobjective optimization called Global WASF-GA ( global weighting achievement scalarizing function genetic algorithm), which falls within the aggregation-based evolutionary algorithms. The main purpose of Global WASF-GA is to approximate the whole Pareto optimal front. Its fitness function is defined by an achievement scalarizing function (ASF) based on the Tchebychev distance, in which two reference points are considered (both utopian and nadir objective vectors) and the weight vector used is taken from a set of weight vectors whose inverses are well-distributed. At each iteration, all individuals are classified into different fronts. Each front is formed by the solutions with the lowest values of the ASF for the different weight vectors in the set, using the utopian vector and the nadir vector as reference points simultaneously. Varying the weight vector in the ASF while considering the utopian and the nadir vectors at the same time enables the algorithm to obtain a final set of nondominated solutions that approximate the whole Pareto optimal front. We compared Global WASF-GA to MOEA/D (different versions) and NSGA-II in two-, three-, and five-objective problems. The computational results obtained permit us to conclude that Global WASF-GA gets better performance, regarding the hypervolume metric and the epsilon indicator, than the other two algorithms in many cases, especially in three- and five-objective problems.

  13. Avoiding spurious submovement decompositions: a globally optimal algorithm

    Rohrer, Brandon Robinson; Hogan, Neville

    2003-01-01

    Evidence for the existence of discrete submovements underlying continuous human movement has motivated many attempts to extract them. Although they produce visually convincing results, all of the methodologies that have been employed are prone to produce spurious decompositions. Examples of potential failures are given. A branch-and-bound algorithm for submovement extraction, capable of global nonlinear minimization (and hence capable of avoiding spurious decompositions), is developed and demonstrated.

  14. Strategies towards an optimized use of the shallow geothermal potential

    Schelenz, S.; Firmbach, L.; Kalbacher, T.; Goerke, U.; Kolditz, O.; Dietrich, P.; Vienken, T.

    2013-12-01

    Thermal use of the shallow subsurface for heat generation, cooling and thermal energy storage is increasingly gaining importance in reconsideration of future energy supplies, e.g. in the course of German energy transition, with application shifting from isolated to intensive use. The planning and dimensioning of (geo-)thermal applications is strongly influenced by the availability of exploration data. Hence, reliable site-specific dimensioning of systems for the thermal use of the shallow subsurface will contribute to an increase in resource efficiency, cost reduction during installation and operation, as well as reduction of environmental impacts and prevention of resource over-exploitation. Despite large cumulative investments that are being made for the utilization of the shallow thermal potential, thermal energy is in many cases exploited without prior on-site exploration and investigation of the local geothermal potential, due to the lack of adequate and cost-efficient exploration techniques. We will present new strategies for an optimized utilization of urban thermal potential, showcased at a currently developed residential neighborhood with high demand for shallow geothermal applications, based on a) enhanced site characterization and b) simulation of different site specific application scenarios. For enhanced site characterization, surface geophysics and vertical high resolution direct push-profiling were combined for reliable determination of aquifer structure and aquifer parameterization. Based on the site characterization, different site specific geothermal application scenarios, including different system types and system configurations, were simulated using OpenGeoSys to guarantee an environmental and economic sustainable thermal use of the shallow subsurface.

  15. Bacterial Quorum Sensing Stabilizes Cooperation by Optimizing Growth Strategies.

    Bruger, Eric L; Waters, Christopher M

    2016-11-15

    Communication has been suggested as a mechanism to stabilize cooperation. In bacteria, chemical communication, termed quorum sensing (QS), has been hypothesized to fill this role, and extracellular public goods are often induced by QS at high cell densities. Here we show, with the bacterium Vibrio harveyi, that QS provides strong resistance against invasion of a QS defector strain by maximizing the cellular growth rate at low cell densities while achieving maximum productivity through protease upregulation at high cell densities. In contrast, QS mutants that act as defectors or unconditional cooperators maximize either the growth rate or the growth yield, respectively, and thus are less fit than the wild-type QS strain. Our findings provide experimental evidence that regulation mediated by microbial communication can optimize growth strategies and stabilize cooperative phenotypes by preventing defector invasion, even under well-mixed conditions. This effect is due to a combination of responsiveness to environmental conditions provided by QS, lowering of competitive costs when QS is not induced, and pleiotropic constraints imposed on defectors that do not perform QS. Cooperation is a fundamental problem for evolutionary biology to explain. Conditional participation through phenotypic plasticity driven by communication is a potential solution to this dilemma. Thus, among bacteria, QS has been proposed to be a proximate stabilizing mechanism for cooperative behaviors. Here, we empirically demonstrate that QS in V. harveyi prevents cheating and subsequent invasion by nonproducing defectors by maximizing the growth rate at low cell densities and the growth yield at high cell densities, whereas an unconditional cooperator is rapidly driven to extinction by defectors. Our findings provide experimental evidence that QS regulation prevents the invasion of cooperative populations by QS defectors even under unstructured conditions, and they strongly support the role of

  16. A Global Optimization Algorithm for Sum of Linear Ratios Problem

    Yuelin Gao; Siqiao Jin

    2013-01-01

    We equivalently transform the sum of linear ratios programming problem into bilinear programming problem, then by using the linear characteristics of convex envelope and concave envelope of double variables product function, linear relaxation programming of the bilinear programming problem is given, which can determine the lower bound of the optimal value of original problem. Therefore, a branch and bound algorithm for solving sum of linear ratios programming problem is put forward, and the c...

  17. Global Optimization for Transport Network Expansion and Signal Setting

    Liu, Haoxiang; Wang, David Z. W.; Yue, Hao

    2015-01-01

    This paper proposes a model to address an urban transport planning problem involving combined network design and signal setting in a saturated network. Conventional transport planning models usually deal with the network design problem and signal setting problem separately. However, the fact that network capacity design and capacity allocation determined by network signal setting combine to govern the transport network performance requires the optimal transport planning to consider the two pr...

  18. Strategies for Combating Global Economic Crisis in Nigeria through ...

    First Lady

    2012-10-27

    Oct 27, 2012 ... cash-productive; boosting the students interest I n science; and developing ... Global economic depression, according to Babalola and Tiamiyu (2009) ... help to overcome the problem of economic crisis in the country? 2.

  19. Global Insurgency Strategy and the Salafi Jihad Movement

    Shultz, Jr, Richard H

    2008-01-01

    ... on a global scale by the Salafi Jihad movement. This work lays out the case that terrorism and insurgency differ, and that the current "long war" is actually being fought by the other side as an insurgency...

  20. Intercultural Communication: A Key Element in Global Strategies.

    Spinks, Nelda; Wells, Barron

    1997-01-01

    Cultural factors in global communication include differences in customs, space, dress, religion, class, work ethic, privacy, and other areas. Language differences in oral, written, and nonverbal communication as well as semantics also complicate intercultural communication. (SK)

  1. USGS global change science strategy: A framework for understanding and responding to climate and land-use change

    Burkett, Virginia R.; Taylor, Ione L.; Belnap, Jayne; Cronin, Thomas M.; Dettinger, Michael D.; Frazier, Eldrich L.; Haines, John W.; Kirtland, David A.; Loveland, Thomas R.; Milly, Paul C.D.; O'Malley, Robin; Thompson, Robert S.

    2011-01-01

    (2007). When science strategies that cover these other components are developed, coordinated implementation will be necessary to achieve Bureau-level synergies and optimize capabilities and expertise.In October 2010, USGS realigned its management and budget structure to implement its 2007 Science Strategy. The new organizational structure, in which “Global Change” is one of seven key mission areas, lends itself to the advancement of the established six strategic goals. USGS global change science is formally represented by the “Climate and Land-Use Change” Mission Area in the FY 2012 budget (USGS, 2011).This plan was developed by the USGS Global Change Science Strategy Planning Team (SSPT) appointed by the USGS Director on March 4, 2010 and charged with developing a Global Change Science Strategy for the coming decade (McNutt, 2010). USGS managers and science staff are the main audience for this science strategy. This document is also intended to serve as the foundation for consistent USGS collaboration and communication with partners and stakeholders.

  2. A Revised Strategy for the Global War on Terrorism

    Maxwell, Jeffrey W

    2007-01-01

    .... A more complete strategy is needed to counter this ideology. New priorities of action include information operations, strategic communications and strengthening societies. These actions will help undermine the enemy's ability to transfer feelings of oppression and hopelessness into hatred and violence. With a balanced strategy, in the long run we will win both the battle of arms and ideas.

  3. Model-based optimization strategy of chiller driven liquid desiccant dehumidifier with genetic algorithm

    Wang, Xinli; Cai, Wenjian; Lu, Jiangang; Sun, Youxian; Zhao, Lei

    2015-01-01

    This study presents a model-based optimization strategy for an actual chiller driven dehumidifier of liquid desiccant dehumidification system operating with lithium chloride solution. By analyzing the characteristics of the components, energy predictive models for the components in the dehumidifier are developed. To minimize the energy usage while maintaining the outlet air conditions at the pre-specified set-points, an optimization problem is formulated with an objective function, the constraints of mechanical limitations and components interactions. Model-based optimization strategy using genetic algorithm is proposed to obtain the optimal set-points for desiccant solution temperature and flow rate, to minimize the energy usage in the dehumidifier. Experimental studies on an actual system are carried out to compare energy consumption between the proposed optimization and the conventional strategies. The results demonstrate that energy consumption using the proposed optimization strategy can be reduced by 12.2% in the dehumidifier operation. - Highlights: • Present a model-based optimization strategy for energy saving in LDDS. • Energy predictive models for components in dehumidifier are developed. • The Optimization strategy are applied and tested in an actual LDDS. • Optimization strategy can achieve energy savings by 12% during operation

  4. Fast globally optimal segmentation of 3D prostate MRI with axial symmetry prior.

    Qiu, Wu; Yuan, Jing; Ukwatta, Eranga; Sun, Yue; Rajchl, Martin; Fenster, Aaron

    2013-01-01

    We propose a novel global optimization approach to segmenting a given 3D prostate T2w magnetic resonance (MR) image, which enforces the inherent axial symmetry of the prostate shape and simultaneously performs a sequence of 2D axial slice-wise segmentations with a global 3D coherence prior. We show that the proposed challenging combinatorial optimization problem can be solved globally and exactly by means of convex relaxation. With this regard, we introduce a novel coupled continuous max-flow model, which is dual to the studied convex relaxed optimization formulation and leads to an efficient multiplier augmented algorithm based on the modern convex optimization theory. Moreover, the new continuous max-flow based algorithm was implemented on GPUs to achieve a substantial improvement in computation. Experimental results using public and in-house datasets demonstrate great advantages of the proposed method in terms of both accuracy and efficiency.

  5. Global issues and opportunities for optimized retinoblastoma care.

    Gallie, Brenda L; Zhao, Junyang; Vandezande, Kirk; White, Abigail; Chan, Helen S L

    2007-12-01

    The RB1 gene is important in all human cancers. Studies of human retinoblastoma point to a rare retinal cell with extreme dependency on RB1 for initiation but not progression to full malignancy. In developed countries, genetic testing within affected families can predict children at high risk of retinoblastoma before birth; chemotherapy with local therapy often saves eyes and vision; and mortality is 4%. In less developed countries where 92% of children with retinoblastoma are born, mortality reaches 90%. Global collaboration is building for the dramatic change in mortality that awareness, simple expertise and therapies could achieve in less developed countries. Copyright 2007 Wiley-Liss, Inc.

  6. Fast globally optimal segmentation of cells in fluorescence microscopy images.

    Bergeest, Jan-Philip; Rohr, Karl

    2011-01-01

    Accurate and efficient segmentation of cells in fluorescence microscopy images is of central importance for the quantification of protein expression in high-throughput screening applications. We propose a new approach for segmenting cell nuclei which is based on active contours and convex energy functionals. Compared to previous work, our approach determines the global solution. Thus, the approach does not suffer from local minima and the segmentation result does not depend on the initialization. We also suggest a numeric approach for efficiently computing the solution. The performance of our approach has been evaluated using fluorescence microscopy images of different cell types. We have also performed a quantitative comparison with previous segmentation approaches.

  7. A Global Optimization Algorithm for Sum of Linear Ratios Problem

    Yuelin Gao

    2013-01-01

    Full Text Available We equivalently transform the sum of linear ratios programming problem into bilinear programming problem, then by using the linear characteristics of convex envelope and concave envelope of double variables product function, linear relaxation programming of the bilinear programming problem is given, which can determine the lower bound of the optimal value of original problem. Therefore, a branch and bound algorithm for solving sum of linear ratios programming problem is put forward, and the convergence of the algorithm is proved. Numerical experiments are reported to show the effectiveness of the proposed algorithm.

  8. The place of physical activity in the WHO Global Strategy on Diet and Physical Activity.

    Bauman, Adrian; Craig, Cora L

    2005-08-24

    In an effort to reduce the global burden of non-communicable disease, the World Health Organization released a Global Strategy for Diet and Physical Activity in May 2004. This commentary reports on the development of the strategy and its importance specifically for physical activity-related work of NGOs and researchers interested in increasing global physical activity participation. Sparked by its work on global efforts to target non-communicable disease prevention in 2000, the World Health Organization commissioned a global strategy on diet and physical activity. The physical activity interest followed efforts that had led to the initial global "Move for Health Day" in 2002. WHO assembled a reference group for the global strategy, and a regional consultation process with countries was undertaken. Underpinning the responses was the need for more physical activity advocacy; partnerships outside of health including urban planning; development of national activity guidelines; and monitoring of the implementation of the strategy. The consultation process was an important mechanism to confirm the importance and elevate the profile of physical activity within the global strategy. It is suggested that separate implementation strategies for diet and physical activity may be needed to work with partner agencies in disparate sectors (e.g. urban planning for physical activity, agriculture for diet). International professional societies are well situated to make an important contribution to global public health by advocating for the importance of physical activity among risk factors; developing international measures of physical activity and global impacts of inactivity; and developing a global research and intervention agenda.

  9. The place of physical activity in the WHO Global Strategy on Diet and Physical Activity

    Craig Cora L

    2005-08-01

    Full Text Available Abstract In an effort to reduce the global burden of non-communicable disease, the World Health Organization released a Global Strategy for Diet and Physical Activity in May 2004. This commentary reports on the development of the strategy and its importance specifically for physical activity-related work of NGOs and researchers interested in increasing global physical activity participation. Sparked by its work on global efforts to target non-communicable disease prevention in 2000, the World Health Organization commissioned a global strategy on diet and physical activity. The physical activity interest followed efforts that had led to the initial global "Move for Health Day" in 2002. WHO assembled a reference group for the global strategy, and a regional consultation process with countries was undertaken. Underpinning the responses was the need for more physical activity advocacy; partnerships outside of health including urban planning; development of national activity guidelines; and monitoring of the implementation of the strategy. The consultation process was an important mechanism to confirm the importance and elevate the profile of physical activity within the global strategy. It is suggested that separate implementation strategies for diet and physical activity may be needed to work with partner agencies in disparate sectors (e.g. urban planning for physical activity, agriculture for diet. International professional societies are well situated to make an important contribution to global public health by advocating for the importance of physical activity among risk factors; developing international measures of physical activity and global impacts of inactivity; and developing a global research and intervention agenda.

  10. Optimal strategy analysis based on robust predictive control for inventory system with random demand

    Saputra, Aditya; Widowati, Sutrisno

    2017-12-01

    In this paper, the optimal strategy for a single product single supplier inventory system with random demand is analyzed by using robust predictive control with additive random parameter. We formulate the dynamical system of this system as a linear state space with additive random parameter. To determine and analyze the optimal strategy for the given inventory system, we use robust predictive control approach which gives the optimal strategy i.e. the optimal product volume that should be purchased from the supplier for each time period so that the expected cost is minimal. A numerical simulation is performed with some generated random inventory data. We simulate in MATLAB software where the inventory level must be controlled as close as possible to a set point decided by us. From the results, robust predictive control model provides the optimal strategy i.e. the optimal product volume that should be purchased and the inventory level was followed the given set point.

  11. Hooke–Jeeves Method-used Local Search in a Hybrid Global Optimization Algorithm

    V. D. Sulimov

    2014-01-01

    Full Text Available Modern methods for optimization investigation of complex systems are based on development and updating the mathematical models of systems because of solving the appropriate inverse problems. Input data desirable for solution are obtained from the analysis of experimentally defined consecutive characteristics for a system or a process. Causal characteristics are the sought ones to which equation coefficients of mathematical models of object, limit conditions, etc. belong. The optimization approach is one of the main ones to solve the inverse problems. In the main case it is necessary to find a global extremum of not everywhere differentiable criterion function. Global optimization methods are widely used in problems of identification and computation diagnosis system as well as in optimal control, computing to-mography, image restoration, teaching the neuron networks, other intelligence technologies. Increasingly complicated systems of optimization observed during last decades lead to more complicated mathematical models, thereby making solution of appropriate extreme problems significantly more difficult. A great deal of practical applications may have the problem con-ditions, which can restrict modeling. As a consequence, in inverse problems the criterion functions can be not everywhere differentiable and noisy. Available noise means that calculat-ing the derivatives is difficult and unreliable. It results in using the optimization methods without calculating the derivatives.An efficiency of deterministic algorithms of global optimization is significantly restrict-ed by their dependence on the extreme problem dimension. When the number of variables is large they use the stochastic global optimization algorithms. As stochastic algorithms yield too expensive solutions, so this drawback restricts their applications. Developing hybrid algo-rithms that combine a stochastic algorithm for scanning the variable space with deterministic local search

  12. Implementation of an optimal control energy management strategy in a hybrid truck

    Mullem, D. van; Keulen, T. van; Kessels, J.T.B.A.; Jager, B. de; Steinbuch, M.

    2010-01-01

    Energy Management Strategies for hybrid powertrains control the power split, between the engine and electric motor, of a hybrid vehicle, with fuel consumption or emission minimization as objective. Optimal control theory can be applied to rewrite the optimization problem to an optimization

  13. Mixed-integer evolution strategies for parameter optimization and their applications to medical image analysis

    Li, Rui

    2009-01-01

    The target of this work is to extend the canonical Evolution Strategies (ES) from traditional real-valued parameter optimization domain to mixed-integer parameter optimization domain. This is necessary because there exist numerous practical optimization problems from industry in which the set of

  14. Multistage and multiobjective formulations of globally optimal upgradable expansions for electric power distribution systems

    Vaziri Yazdi Pin, Mohammad

    Electric power distribution systems are the last high voltage link in the chain of production, transport, and delivery of the electric energy, the fundamental goals of which are to supply the users' demand safely, reliably, and economically. The number circuit miles traversed by distribution feeders in the form of visible overhead or imbedded underground lines, far exceed those of all other bulk transport circuitry in the transmission system. Development and expansion of the distribution systems, similar to other systems, is directly proportional to the growth in demand and requires careful planning. While growth of electric demand has recently slowed through efforts in the area of energy management, the need for a continued expansion seems inevitable for the near future. Distribution system and expansions are also independent of current issues facing both the suppliers and the consumers of electrical energy. For example, deregulation, as an attempt to promote competition by giving more choices to the consumers, while it will impact the suppliers' planning strategies, it cannot limit the demand growth or the system expansion in the global sense. Curiously, despite presence of technological advancements and a 40-year history of contributions in the area, many of the major utilities still relay on experience and resort to rudimentary techniques when planning expansions. A comprehensive literature review of the contributions and careful analyses of the proposed algorithms for distribution expansion, confirmed that the problem is a complex, multistage and multiobjective problem for which a practical solution remains to be developed. In this research, based on the 15-year experience of a utility engineer, the practical expansion problem has been clearly defined and the existing deficiencies in the previous work identified and analyzed. The expansion problem has been formulated as a multistage planning problem in line with a natural course of development and industry

  15. Anodic Cyclization Reactions and the Mechanistic Strategies That Enable Optimization.

    Feng, Ruozhu; Smith, Jake A; Moeller, Kevin D

    2017-09-19

    Oxidation reactions are powerful tools for synthesis because they allow us to reverse the polarity of electron-rich functional groups, generate highly reactive intermediates, and increase the functionality of molecules. For this reason, oxidation reactions have been and continue to be the subject of intense study. Central to these efforts is the development of mechanism-based strategies that allow us to think about the reactive intermediates that are frequently central to the success of the reactions and the mechanistic pathways that those intermediates trigger. For example, consider oxidative cyclization reactions that are triggered by the removal of an electron from an electron-rich olefin and lead to cyclic products that are functionalized for further elaboration. For these reactions to be successful, the radical cation intermediate must first be generated using conditions that limit its polymerization and then channeled down a productive desired pathway. Following the cyclization, a second oxidation step is necessary for product formation, after which the resulting cation must be quenched in a controlled fashion to avoid undesired elimination reactions. Problems can arise at any one or all of these steps, a fact that frequently complicates reaction optimization and can discourage the development of new transformations. Fortunately, anodic electrochemistry offers an outstanding opportunity to systematically probe the mechanism of oxidative cyclization reactions. The use of electrochemical methods allows for the generation of radical cations under neutral conditions in an environment that helps prevent polymerization of the intermediate. Once the intermediates have been generated, a series of "telltale indicators" can be used to diagnose which step in an oxidative cyclization is problematic for less successful transformation. A set of potential solutions to address each type of problem encountered has been developed. For example, problems with the initial

  16. Global Obesity Study on Drivers for Weight Reduction Strategies

    Carola Grebitus

    2015-01-01

    Full Text Available Objective: To assess factors determining the reaction of individuals to the threats of overweight and obesity and to examine the interdependencies between weight-reducing strategies. Methods: Cross-country survey covering 19 countries and 13,155 interviews. Data were analysed using a bivariate probit model that allows simultaneously analysing two weight-reducing strategies. Results: Results show that weight-reducing strategies chosen are not independent from each other. Findings also reveal that different strategies are chosen by different population segments. Women are more likely to change their dietary patterns and less likely to become physically active after surpassing a weight threshold. In addition, the probability of a dietary change in case of overweight differs considerably between countries. The study also reveals that attitudes are an important factor for the strategy choice. Conclusions: It is vital for public health policies to understand determinants of citizens' engagement in weight reduction strategies once a certain threshold is reached. Thus, results can support the design of public health campaigns and programmes that aim to change community or national health behaviour trends taking into account, e.g., national differences.

  17. Vertical bifacial solar farms: Physics, design, and global optimization

    Khan, M. Ryyan

    2017-09-04

    There have been sustained interest in bifacial solar cell technology since 1980s, with prospects of 30–50% increase in the output power from a stand-alone panel. Moreover, a vertical bifacial panel reduces dust accumulation and provides two output peaks during the day, with the second peak aligned to the peak electricity demand. Recent commercialization and anticipated growth of bifacial panel market have encouraged a closer scrutiny of the integrated power-output and economic viability of bifacial solar farms, where mutual shading will erode some of the anticipated energy gain associated with an isolated, single panel. Towards that goal, in this paper we focus on geography-specific optimization of ground-mounted vertical bifacial solar farms for the entire world. For local irradiance, we combine the measured meteorological data with the clear-sky model. In addition, we consider the effects of direct, diffuse, and albedo light. We assume the panel is configured into sub-strings with bypass-diodes. Based on calculated light collection and panel output, we analyze the optimum farm design for maximum yearly output at any given location in the world. Our results predict that, regardless of the geographical location, a vertical bifacial farm will yield 10–20% more energy than a traditional monofacial farm for a practical row-spacing of 2 m (corresponding to 1.2 m high panels). With the prospect of additional 5–20% energy gain from reduced soiling and tilt optimization, bifacial solar farm do offer a viable technology option for large-scale solar energy generation.

  18. Offshore Wind Farm Layout Design Considering Optimized Power Dispatch Strategy

    Hou, Peng; Hu, Weihao; N. Soltani, Mohsen

    2017-01-01

    Offshore wind farm has drawn more and more attention recently due to its higher energy capacity and more freedom to occupy area. However, the investment is higher. In order to make a cost-effective wind farm, the wind farm layout should be optimized. The wake effect is one of the dominant factors...... leading to energy losses. It is expected that the optimized placement of wind turbines (WT) over a large sea area can lead to the best tradeoff between energy yields and capital investment. This paper proposes a novel way to position offshore WTs for a regular shaped wind farm. In addition to optimizing...... the direction of wind farm placement and the spacing between WTs, the control strategy’s impact on energy yields is also discussed. Since the problem is non-convex and lots of optimization variables are involved, an evolutionary algorithm, the particle swarm optimization algorithm (PSO), is adopted to find...

  19. Chaos optimization algorithms based on chaotic maps with different probability distribution and search speed for global optimization

    Yang, Dixiong; Liu, Zhenjun; Zhou, Jilei

    2014-04-01

    Chaos optimization algorithms (COAs) usually utilize the chaotic map like Logistic map to generate the pseudo-random numbers mapped as the design variables for global optimization. Many existing researches indicated that COA can more easily escape from the local minima than classical stochastic optimization algorithms. This paper reveals the inherent mechanism of high efficiency and superior performance of COA, from a new perspective of both the probability distribution property and search speed of chaotic sequences generated by different chaotic maps. The statistical property and search speed of chaotic sequences are represented by the probability density function (PDF) and the Lyapunov exponent, respectively. Meanwhile, the computational performances of hybrid chaos-BFGS algorithms based on eight one-dimensional chaotic maps with different PDF and Lyapunov exponents are compared, in which BFGS is a quasi-Newton method for local optimization. Moreover, several multimodal benchmark examples illustrate that, the probability distribution property and search speed of chaotic sequences from different chaotic maps significantly affect the global searching capability and optimization efficiency of COA. To achieve the high efficiency of COA, it is recommended to adopt the appropriate chaotic map generating the desired chaotic sequences with uniform or nearly uniform probability distribution and large Lyapunov exponent.

  20. Statistical strategies for global monitoring of tropical forests

    Raymond L. Czaplewski

    1991-01-01

    The Food and Agricultural Organization (FAO) of the United Nations is conducting a global assessment of tropical forest resources, which will be accomplished by mid-1992. This assessment requires, in part, estimates of the total area of tropical forest cover in 1990, and the rate of change in forest cover between 1980 and 1990. This paper describes: (1) the strategic...

  1. The Global Enery and Water Cycle Experiment Science Strategy

    Chahine, M. T.

    1997-01-01

    The distribution of water in the atmosphere and at the surface of the Earth is the most influential factor regulating our environment, not only because water is essential for life but also because through phase transitions it is the main energy source that control clouds and radiation and drives the global circulation of the atmosphere.

  2. A strategy for global environmental education at the university

    Hussain, S.T.; Hayes, R.L.

    1993-01-01

    The Earth's environment is a dynamic system that is affected both by natural phenomena and by human activity. The changes occurring in the global environment are bound to have serious consequences for all its inhabitants. Therefore, the world is rapidly becoming interdependent. Multidisciplinary scientific efforts must be directed toward understanding these global environmental changes. These efforts will require sufficient funds to attract scientists into global environmental research and to disseminate new knowledge to future scholars and to the general public alike. The federal government has a definite role to play in this effort and should allocate sufficient funds to initiate and sustain these programs. Unfortunately, such funds are not currently budgeted. The academic department, as the basic structural and functional unit of the American university system, is most appropriate to ensure environmental educational goals. The authors propose the establishment of a novel Department of Global Environment at every university. That department must be multidisciplinary in nature and must accumulate a critical mass of scholars from all relevant traditional disciplines in the arts and sciences to generate knowledge, to educate students, and to provide advisory services to policy makers. The study product of this department should receive a broad-based education and should emerge as an informed individual who possesses sufficient skills to achieve sustainable communities. That student should also be equipped to assume leadership and to formulate policy about global environmental issues. The investment in education may well be the only way to secure a future for humanity and for the natural world as we now know it

  3. Finding optimal vaccination strategies for pandemic influenza using genetic algorithms.

    Patel, Rajan; Longini, Ira M; Halloran, M Elizabeth

    2005-05-21

    In the event of pandemic influenza, only limited supplies of vaccine may be available. We use stochastic epidemic simulations, genetic algorithms (GA), and random mutation hill climbing (RMHC) to find optimal vaccine distributions to minimize the number of illnesses or deaths in the population, given limited quantities of vaccine. Due to the non-linearity, complexity and stochasticity of the epidemic process, it is not possible to solve for optimal vaccine distributions mathematically. However, we use GA and RMHC to find near optimal vaccine distributions. We model an influenza pandemic that has age-specific illness attack rates similar to the Asian pandemic in 1957-1958 caused by influenza A(H2N2), as well as a distribution similar to the Hong Kong pandemic in 1968-1969 caused by influenza A(H3N2). We find the optimal vaccine distributions given that the number of doses is limited over the range of 10-90% of the population. While GA and RMHC work well in finding optimal vaccine distributions, GA is significantly more efficient than RMHC. We show that the optimal vaccine distribution found by GA and RMHC is up to 84% more effective than random mass vaccination in the mid range of vaccine availability. GA is generalizable to the optimization of stochastic model parameters for other infectious diseases and population structures.

  4. A global optimization method for evaporative cooling systems based on the entransy theory

    Yuan, Fang; Chen, Qun

    2012-01-01

    Evaporative cooling technique, one of the most widely used methods, is essential to both energy conservation and environment protection. This contribution introduces a global optimization method for indirect evaporative cooling systems with coupled heat and mass transfer processes based on the entransy theory to improve their energy efficiency. First, we classify the irreversible processes in the system into the heat transfer process, the coupled heat and mass transfer process and the mixing process of waters in different branches, where the irreversibility is evaluated by the entransy dissipation. Then through the total system entransy dissipation, we establish the theoretical relationship of the user demands with both the geometrical structures of each heat exchanger and the operating parameters of each fluid, and derive two optimization equation groups focusing on two typical optimization problems. Finally, an indirect evaporative cooling system is taken as an example to illustrate the applications of the newly proposed optimization method. It is concluded that there exists an optimal circulating water flow rate with the minimum total thermal conductance of the system. Furthermore, with different user demands and moist air inlet conditions, it is the global optimization, other than parametric analysis, will obtain the optimal performance of the system. -- Highlights: ► Introduce a global optimization method for evaporative cooling systems. ► Establish the direct relation between user demands and the design parameters. ► Obtain two groups of optimization equations for two typical optimization objectives. ► Solving the equations offers the optimal design parameters for the system. ► Provide the instruction for the design of coupled heat and mass transfer systems.

  5. A theoretical global optimization method for vapor-compression refrigeration systems based on entransy theory

    Xu, Yun-Chao; Chen, Qun

    2013-01-01

    The vapor-compression refrigeration systems have been one of the essential energy conversion systems for humankind and exhausting huge amounts of energy nowadays. Surrounding the energy efficiency promotion of the systems, there are lots of effectual optimization methods but mainly relied on engineering experience and computer simulations rather than theoretical analysis due to the complex and vague physical essence. We attempt to propose a theoretical global optimization method based on in-depth physical analysis for the involved physical processes, i.e. heat transfer analysis for condenser and evaporator, through introducing the entransy theory and thermodynamic analysis for compressor and expansion valve. The integration of heat transfer and thermodynamic analyses forms the overall physical optimization model for the systems to describe the relation between all the unknown parameters and known conditions, which makes theoretical global optimization possible. With the aid of the mathematical conditional extremum solutions, an optimization equation group and the optimal configuration of all the unknown parameters are analytically obtained. Eventually, via the optimization of a typical vapor-compression refrigeration system with various working conditions to minimize the total heat transfer area of heat exchangers, the validity and superior of the newly proposed optimization method is proved. - Highlights: • A global optimization method for vapor-compression systems is proposed. • Integrating heat transfer and thermodynamic analyses forms the optimization model. • A mathematical relation between design parameters and requirements is derived. • Entransy dissipation is introduced into heat transfer analysis. • The validity of the method is proved via optimization of practical cases

  6. A global strategy for the European PV industry

    Viaud, M.; Despotou, E.; Latour, M.; Hoffmann, W.; Macias, E.; Cameron, M.; Laborde, E.

    2004-01-01

    The objective was to develop a comprehensive strategy that answers to the need of today European PV industry. Namely: - Develop PV markets in Europe - Develop export markets. - Position the European PV industry within the European political environment and support the effort of national actors in their local objectives. This method lends itself to brainstorming to create actions and synergies, on order to achieve strategy objectives. The whole work is based on working groups clearly defined on the purpose, where all EPIA members are invited to participate. The overall first results are presented during the 19. EU PV Conference in Paris and EPIA will do recommendations on actions to be undertaken in the future. This strategy is co-financed by EPIA members and the 6. Framework Programme for research of the European Commission through the PV Catapult project. (authors)

  7. Relationship Between Competitive Strategies and the Success Perception of Polish Born Globals

    Baranowska-Prokop Ewa

    2014-09-01

    Full Text Available The key objective of this paper is to describe and evaluate the competitive strategies applied by Polish born global enterprises. To reveal these strategies, two competitive models developed by M.E. Porter are applied to an original data set obtained from 256 small and medium Polish enterprises through a survey employing the CATI technique. The outcomes of these strategies, as perceived by the companies applying them, are also evaluated against two hypotheses. We conclude that Polish firms apply both basic strategies of competition, i.e. cost leadership strategies and differentiation strategies and that a substantial majority of companies perceive themselves to have succeeded on the market.

  8. Globally optimal, minimum stored energy, double-doughnut superconducting magnets.

    Tieng, Quang M; Vegh, Viktor; Brereton, Ian M

    2010-01-01

    The use of the minimum stored energy current density map-based methodology of designing closed-bore symmetric superconducting magnets was described recently. The technique is further developed to cater for the design of interventional-type MRI systems, and in particular open symmetric magnets of the double-doughnut configuration. This extends the work to multiple magnet domain configurations. The use of double-doughnut magnets in MRI scanners has previously been hindered by the ability to deliver strong magnetic fields over a sufficiently large volume appropriate for imaging, essentially limiting spatial resolution, signal-to-noise ratio, and field of view. The requirement of dedicated interventional space restricts the manner in which the coils can be arranged and placed. The minimum stored energy optimal coil arrangement ensures that the field strength is maximized over a specific region of imaging. The design method yields open, dual-domain magnets capable of delivering greater field strengths than those used prior to this work, and at the same time it provides an increase in the field-of-view volume. Simulation results are provided for 1-T double-doughnut magnets with at least a 50-cm 1-ppm (parts per million) field of view and 0.7-m gap between the two doughnuts. Copyright (c) 2009 Wiley-Liss, Inc.

  9. The German government's global health strategy--a strategy also to support research and development for neglected diseases?

    Fehr, Angela; Razum, Oliver

    2014-01-01

    Neglected tropical infectious diseases as well as rare diseases are characterized by structural research and development (R&D) deficits. The market fails for these disease groups. Consequently, to meet public health and individual patient needs, political decision makers have to develop strategies at national and international levels to make up for this R&D deficit. The German government recently published its first global health strategy. The strategy underlines the German government's commitment to strengthening global health governance. We find, however, that the strategy lacks behind the international public health endeavors for neglected diseases. It fails to make reference to the ongoing debate on a global health agreement. Neither does it outline a comprehensive national strategy to promote R&D into neglected diseases, which would integrate existing R&D activities in Germany and link up to the international debate on sustainable, needs-based R&D and affordable access. This despite the fact that only recently, in a consensus-building process, a National Plan of Action for rare diseases was successfully developed in Germany which could serve as a blueprint for a similar course of action for neglected diseases. We recommend that, without delay, a structured process be initiated in Germany to explore all options to promote R&D for neglected diseases, including a global health agreement.

  10. The German government's global health strategy – a strategy also to support research and development for neglected diseases?

    Angela Fehr

    2014-07-01

    Full Text Available Neglected tropical infectious diseases as well as rare diseases are characterized by structural research and development (R&D deficits. The market fails for these disease groups. Consequently, to meet public health and individual patient needs, political decision makers have to develop strategies at national and international levels to make up for this R&D deficit. The German government recently published its first global health strategy. The strategy underlines the German government's commitment to strengthening global health governance. We find, however, that the strategy lacks behind the international public health endeavors for neglected diseases. It fails to make reference to the ongoing debate on a global health agreement. Neither does it outline a comprehensive national strategy to promote R&D into neglected diseases, which would integrate existing R&D activities in Germany and link up to the international debate on sustainable, needs-based R&D and affordable access. This despite the fact that only recently, in a consensus-building process, a National Plan of Action for rare diseases was successfully developed in Germany which could serve as a blueprint for a similar course of action for neglected diseases. We recommend that, without delay, a structured process be initiated in Germany to explore all options to promote R&D for neglected diseases, including a global health agreement.

  11. Strategies for high-precision Global Positioning System orbit determination

    Lichten, Stephen M.; Border, James S.

    1987-01-01

    Various strategies for the high-precision orbit determination of the GPS satellites are explored using data from the 1985 GPS field test. Several refinements to the orbit determination strategies were found to be crucial for achieving high levels of repeatability and accuracy. These include the fine tuning of the GPS solar radiation coefficients and the ground station zenith tropospheric delays. Multiday arcs of 3-6 days provided better orbits and baselines than the 8-hr arcs from single-day passes. Highest-quality orbits and baselines were obtained with combined carrier phase and pseudorange solutions.

  12. [Global brain metastases management strategy: a multidisciplinary-based approach].

    Métellus, P; Tallet, A; Dhermain, F; Reyns, N; Carpentier, A; Spano, J-P; Azria, D; Noël, G; Barlési, F; Taillibert, S; Le Rhun, É

    2015-02-01

    Brain metastases management has evolved over the last fifteen years and may use varying strategies, including more or less aggressive treatments, sometimes combined, leading to an improvement in patient's survival and quality of life. The therapeutic decision is subject to a multidisciplinary analysis, taking into account established prognostic factors including patient's general condition, extracerebral disease status and clinical and radiological presentation of lesions. In this article, we propose a management strategy based on the state of current knowledge and available therapeutic resources. Copyright © 2015. Published by Elsevier SAS.

  13. Optimal Software Strategies in the Presence of Network Externalities

    Liu, Yipeng

    2009-01-01

    Network externalities or alternatively termed network effects are pervasive in computer software markets. While software vendors consider pricing strategies, they must also take into account the impact of network externalities on their sales. My main interest in this research is to describe a firm's strategies and behaviors in the presence of…

  14. Optimizing the stirring strategy for the vibrating intrinsic reverberation chamber

    Serra, Ramiro; Serra, Ramiro; Leferink, Frank Bernardus Johannes

    2010-01-01

    This work describes the definition, application and assessment of a factorial plan with the aim of gaining insight on what kind of stirring strategy could work the best in a vibrating intrinsic reverberation chamber. Three different stirring strategies were defined as factors of a factorial

  15. Self-adaptive global best harmony search algorithm applied to reactor core fuel management optimization

    Poursalehi, N.; Zolfaghari, A.; Minuchehr, A.; Valavi, K.

    2013-01-01

    Highlights: • SGHS enhanced the convergence rate of LPO using some improvements in comparison to basic HS and GHS. • SGHS optimization algorithm obtained averagely better fitness relative to basic HS and GHS algorithms. • Upshot of the SGHS implementation in the LPO reveals its flexibility, efficiency and reliability. - Abstract: The aim of this work is to apply the new developed optimization algorithm, Self-adaptive Global best Harmony Search (SGHS), for PWRs fuel management optimization. SGHS algorithm has some modifications in comparison with basic Harmony Search (HS) and Global-best Harmony Search (GHS) algorithms such as dynamically change of parameters. For the demonstration of SGHS ability to find an optimal configuration of fuel assemblies, basic Harmony Search (HS) and Global-best Harmony Search (GHS) algorithms also have been developed and investigated. For this purpose, Self-adaptive Global best Harmony Search Nodal Expansion package (SGHSNE) has been developed implementing HS, GHS and SGHS optimization algorithms for the fuel management operation of nuclear reactor cores. This package uses developed average current nodal expansion code which solves the multi group diffusion equation by employment of first and second orders of Nodal Expansion Method (NEM) for two dimensional, hexagonal and rectangular geometries, respectively, by one node per a FA. Loading pattern optimization was performed using SGHSNE package for some test cases to present the SGHS algorithm capability in converging to near optimal loading pattern. Results indicate that the convergence rate and reliability of the SGHS method are quite promising and practically, SGHS improves the quality of loading pattern optimization results relative to HS and GHS algorithms. As a result, it has the potential to be used in the other nuclear engineering optimization problems

  16. Global parameter optimization for maximizing radioisotope detection probabilities at fixed false alarm rates

    Portnoy, David, E-mail: david.portnoy@jhuapl.edu [Johns Hopkins University Applied Physics Laboratory, 11100 Johns Hopkins Road, Laurel, MD 20723 (United States); Feuerbach, Robert; Heimberg, Jennifer [Johns Hopkins University Applied Physics Laboratory, 11100 Johns Hopkins Road, Laurel, MD 20723 (United States)

    2011-10-01

    Today there is a tremendous amount of interest in systems that can detect radiological or nuclear threats. Many of these systems operate in extremely high throughput situations where delays caused by false alarms can have a significant negative impact. Thus, calculating the tradeoff between detection rates and false alarm rates is critical for their successful operation. Receiver operating characteristic (ROC) curves have long been used to depict this tradeoff. The methodology was first developed in the field of signal detection. In recent years it has been used increasingly in machine learning and data mining applications. It follows that this methodology could be applied to radiological/nuclear threat detection systems. However many of these systems do not fit into the classic principles of statistical detection theory because they tend to lack tractable likelihood functions and have many parameters, which, in general, do not have a one-to-one correspondence with the detection classes. This work proposes a strategy to overcome these problems by empirically finding parameter values that maximize the probability of detection for a selected number of probabilities of false alarm. To find these parameter values a statistical global optimization technique that seeks to estimate portions of a ROC curve is proposed. The optimization combines elements of simulated annealing with elements of genetic algorithms. Genetic algorithms were chosen because they can reduce the risk of getting stuck in local minima. However classic genetic algorithms operate on arrays of Booleans values or bit strings, so simulated annealing is employed to perform mutation in the genetic algorithm. The presented initial results were generated using an isotope identification algorithm developed at Johns Hopkins University Applied Physics Laboratory. The algorithm has 12 parameters: 4 real-valued and 8 Boolean. A simulated dataset was used for the optimization study; the 'threat' set of

  17. Global parameter optimization for maximizing radioisotope detection probabilities at fixed false alarm rates

    Portnoy, David; Feuerbach, Robert; Heimberg, Jennifer

    2011-01-01

    Today there is a tremendous amount of interest in systems that can detect radiological or nuclear threats. Many of these systems operate in extremely high throughput situations where delays caused by false alarms can have a significant negative impact. Thus, calculating the tradeoff between detection rates and false alarm rates is critical for their successful operation. Receiver operating characteristic (ROC) curves have long been used to depict this tradeoff. The methodology was first developed in the field of signal detection. In recent years it has been used increasingly in machine learning and data mining applications. It follows that this methodology could be applied to radiological/nuclear threat detection systems. However many of these systems do not fit into the classic principles of statistical detection theory because they tend to lack tractable likelihood functions and have many parameters, which, in general, do not have a one-to-one correspondence with the detection classes. This work proposes a strategy to overcome these problems by empirically finding parameter values that maximize the probability of detection for a selected number of probabilities of false alarm. To find these parameter values a statistical global optimization technique that seeks to estimate portions of a ROC curve is proposed. The optimization combines elements of simulated annealing with elements of genetic algorithms. Genetic algorithms were chosen because they can reduce the risk of getting stuck in local minima. However classic genetic algorithms operate on arrays of Booleans values or bit strings, so simulated annealing is employed to perform mutation in the genetic algorithm. The presented initial results were generated using an isotope identification algorithm developed at Johns Hopkins University Applied Physics Laboratory. The algorithm has 12 parameters: 4 real-valued and 8 Boolean. A simulated dataset was used for the optimization study; the 'threat' set of spectra

  18. Global parameter optimization for maximizing radioisotope detection probabilities at fixed false alarm rates

    Portnoy, David; Feuerbach, Robert; Heimberg, Jennifer

    2011-10-01

    Today there is a tremendous amount of interest in systems that can detect radiological or nuclear threats. Many of these systems operate in extremely high throughput situations where delays caused by false alarms can have a significant negative impact. Thus, calculating the tradeoff between detection rates and false alarm rates is critical for their successful operation. Receiver operating characteristic (ROC) curves have long been used to depict this tradeoff. The methodology was first developed in the field of signal detection. In recent years it has been used increasingly in machine learning and data mining applications. It follows that this methodology could be applied to radiological/nuclear threat detection systems. However many of these systems do not fit into the classic principles of statistical detection theory because they tend to lack tractable likelihood functions and have many parameters, which, in general, do not have a one-to-one correspondence with the detection classes. This work proposes a strategy to overcome these problems by empirically finding parameter values that maximize the probability of detection for a selected number of probabilities of false alarm. To find these parameter values a statistical global optimization technique that seeks to estimate portions of a ROC curve is proposed. The optimization combines elements of simulated annealing with elements of genetic algorithms. Genetic algorithms were chosen because they can reduce the risk of getting stuck in local minima. However classic genetic algorithms operate on arrays of Booleans values or bit strings, so simulated annealing is employed to perform mutation in the genetic algorithm. The presented initial results were generated using an isotope identification algorithm developed at Johns Hopkins University Applied Physics Laboratory. The algorithm has 12 parameters: 4 real-valued and 8 Boolean. A simulated dataset was used for the optimization study; the "threat" set of spectra

  19. Optimal Pricing Strategies for New Products in Dynamic Oligopolies

    Engelbert Dockner; Steffen Jørgensen

    1988-01-01

    This paper deals with the determination of optimal pricing policies for firms in oligopolistic markets. The problem is studied as a differential game and optimal pricing policies are established as Nash open-loop controls. Cost learning effects are assumed such that unit costs are decreasing with cumulative output. Discounting of future profits is also taken into consideration. Initially, the problem is addressed in a general framework, and we proceed to study some specific cases that are rel...

  20. Global warming mitigation strategies and programs for power plant developers

    Holmes, N.R.

    1992-01-01

    Power plant developers are increasingly being surprised by regulatory agencies requiring them to mitigate the carbon dioxide(CO 2 ) emissions from their proposed power plants, as part of the plant's operating permit conditions. Since carbon dioxide is not a criteria pollutant with a National Ambient Air Quality Standard, power plant developers are often troubled by this additional regulatory requirement. This presentation will describe the contribution that CO 2 makes to global warming, the role of trees and forests as carbon sequesters or sinks, some non-forestry related and forestry related mitigation programs, including the advantages, disadvantages, and some cost estimates for the forestry related CO 2 mitigation programs. As public concern about global warming continues to escalate, it is almost certain that regulatory agencies will increase their focus on CO 2 mitigation

  1. Novel Adaptive Bacteria Foraging Algorithms for Global Optimization

    Ahmad N. K. Nasir

    2014-01-01

    Full Text Available This paper presents improved versions of bacterial foraging algorithm (BFA. The chemotaxis feature of bacteria through random motion is an effective strategy for exploring the optimum point in a search area. The selection of small step size value in the bacteria motion leads to high accuracy in the solution but it offers slow convergence. On the contrary, defining a large step size in the motion provides faster convergence but the bacteria will be unable to locate the optimum point hence reducing the fitness accuracy. In order to overcome such problems, novel linear and nonlinear mathematical relationships based on the index of iteration, index of bacteria, and fitness cost are adopted which can dynamically vary the step size of bacteria movement. The proposed algorithms are tested with several unimodal and multimodal benchmark functions in comparison with the original BFA. Moreover, the application of the proposed algorithms in modelling of a twin rotor system is presented. The results show that the proposed algorithms outperform the predecessor algorithm in all test functions and acquire better model for the twin rotor system.

  2. Multi-Objective Optimization of Start-up Strategy for Pumped Storage Units

    Jinjiao Hou

    2018-05-01

    Full Text Available This paper proposes a multi-objective optimization method for the start-up strategy of pumped storage units (PSU for the first time. In the multi-objective optimization method, the speed rise time and the overshoot during the process of the start-up are taken as the objectives. A precise simulation platform is built for simulating the transient process of start-up, and for calculating the objectives based on the process. The Multi-objective Particle Swarm Optimization algorithm (MOPSO is adopted to optimize the widely applied start-up strategies based on one-stage direct guide vane control (DGVC, and two-stage DGVC. Based on the Pareto Front obtained, a multi-objective decision-making method based on the relative objective proximity is used to sort the solutions in the Pareto Front. Start-up strategy optimization for a PSU of a pumped storage power station in Jiangxi Province in China is conducted in experiments. The results show that: (1 compared with the single objective optimization, the proposed multi-objective optimization of start-up strategy not only greatly shortens the speed rise time and the speed overshoot, but also makes the speed curve quickly stabilize; (2 multi-objective optimization of strategy based on two-stage DGVC achieves better solution for a quick and smooth start-up of PSU than that of the strategy based on one-stage DGVC.

  3. Simulation Modeling to Compare High-Throughput, Low-Iteration Optimization Strategies for Metabolic Engineering.

    Heinsch, Stephen C; Das, Siba R; Smanski, Michael J

    2018-01-01

    Increasing the final titer of a multi-gene metabolic pathway can be viewed as a multivariate optimization problem. While numerous multivariate optimization algorithms exist, few are specifically designed to accommodate the constraints posed by genetic engineering workflows. We present a strategy for optimizing expression levels across an arbitrary number of genes that requires few design-build-test iterations. We compare the performance of several optimization algorithms on a series of simulated expression landscapes. We show that optimal experimental design parameters depend on the degree of landscape ruggedness. This work provides a theoretical framework for designing and executing numerical optimization on multi-gene systems.

  4. Global Salafist Jihad in UK -- Strategies of Prevention

    2007-05-24

    global Jihadist movement has become decentralised and more diffuse, events in Iraq are shaping a new generation of terrorist leaders and operatives...Qaeda’s(pl~ers could conceive, plan and prepare attacks. Germany was favoured due to their security forces’ ignorance ofMiddle Eastern networks - most...social value, there is little intellectkI energy devoted to a better understanding of radicalisation and methods to blunt its ¢ffect, a paucity of

  5. Global Corporate Priorities and Demand-Led Learning Strategies

    Dealtry, Richard

    2008-01-01

    Purpose: The purpose of this article is to start the process of exploring how to optimise connections between the strategic needs of an organisation as directed by top management and its learning management structures and strategies. Design/methodology/approach: The article takes a broad brush approach to a complex and large subject area that is…

  6. Slowing global warming. Mitigation strategy for the developing world

    Pachauri, R.K.; Barathan, S.

    1995-01-01

    Globally, a range of human activities that characterize modern economic systems are leading to emissions of greenhouse gases. For some activities like the cultivation of paddy rice in flooded soils, there is reason to believe that there are no economically viable or practical alternatives to the current methods which produce these emissions. However, there are several other areas of human activity ranging from the generation of electricity to the provision of passenger and freight transport, in which there clearly exists the potential for preparing the agenda for change which would mitigate global warming. The objective of this paper is to discuss and evaluate a suitable mix of innovative measures which would make efficient use of scarce resources and maximize returns from the resources invested to limit CO 2 emissions. In particular, this paper evolves a three phase approach for mitigating CO 2 emissions that can be widely applied to reorient economic development policies in the developing world. Comprising an agenda for change, it underlines specific failures in national policies, identifies thrust areas for mitigating CO 2 emissions and suggests policy responses in major sectors of the economy. The guiding premise here is simple and straightforward - the energy sector (inclusive of the services provided by energy rather than energy per se) which has been a major cause for invoking the threat of climate change and global warming, must now become a part of the solution. (au) 11 refs

  7. Optimal operation strategies of compressed air energy storage (CAES) on electricity spot markets with fluctuating prices

    Lund, Henrik; Salgi, Georges; Elmegaard, Brian

    2009-01-01

    on electricity spot markets by storing energy when electricity prices are low and producing electricity when prices are high. In order to make a profit on such markets, CAES plant operators have to identify proper strategies to decide when to sell and when to buy electricity. This paper describes three...... plants will not be able to achieve such optimal operation, since the fluctuations of spot market prices in the coming hours and days are not known. Consequently, two simple practical strategies have been identified and compared to the results of the optimal strategy. This comparison shows that...... independent computer-based methodologies which may be used for identifying the optimal operation strategy for a given CAES plant, on a given spot market and in a given year. The optimal strategy is identified as the one which provides the best business-economic net earnings for the plant. In practice, CAES...

  8. The Global Optimal Algorithm of Reliable Path Finding Problem Based on Backtracking Method

    Liang Shen

    2017-01-01

    Full Text Available There is a growing interest in finding a global optimal path in transportation networks particularly when the network suffers from unexpected disturbance. This paper studies the problem of finding a global optimal path to guarantee a given probability of arriving on time in a network with uncertainty, in which the travel time is stochastic instead of deterministic. Traditional path finding methods based on least expected travel time cannot capture the network user’s risk-taking behaviors in path finding. To overcome such limitation, the reliable path finding algorithms have been proposed but the convergence of global optimum is seldom addressed in the literature. This paper integrates the K-shortest path algorithm into Backtracking method to propose a new path finding algorithm under uncertainty. The global optimum of the proposed method can be guaranteed. Numerical examples are conducted to demonstrate the correctness and efficiency of the proposed algorithm.

  9. Global Strategy for the Diagnosis, Management and Prevention of Chronic Obstructive Pulmonary Disease, GOLD Executive Summary

    Vestbo, Jørgen; Hurd, Suzanne S; Agusti, Alvar G

    2013-01-01

    Chronic obstructive pulmonary disease (COPD) is a global health problem and since 2001 the Global Initiative for Chronic Obstructive Lung Disease (GOLD) has published its strategy document for the diagnosis and management of COPD. This executive summary presents the main contents of the second 5...

  10. Evaluating Strategies for Achieving Global Collective Action on Transnational Health Threats and Social Inequalities

    Hoffman, Steven Justin

    2015-01-01

    This dissertation presents three studies that evaluate different strategies for addressing transnational health threats and social inequalities that depend upon or would benefit from global collective action. Each draws upon different academic disciplines, methods and epistemological traditions. Chapter 1 assesses the role of international law in addressing global health challenges, specifically examining when, how and why global health treaties may be helpful. Evidence from 90 quantitati...

  11. A branch and bound algorithm for the global optimization of Hessian Lipschitz continuous functions

    Fowkes, Jaroslav M.

    2012-06-21

    We present a branch and bound algorithm for the global optimization of a twice differentiable nonconvex objective function with a Lipschitz continuous Hessian over a compact, convex set. The algorithm is based on applying cubic regularisation techniques to the objective function within an overlapping branch and bound algorithm for convex constrained global optimization. Unlike other branch and bound algorithms, lower bounds are obtained via nonconvex underestimators of the function. For a numerical example, we apply the proposed branch and bound algorithm to radial basis function approximations. © 2012 Springer Science+Business Media, LLC.

  12. Optimal Strategy Analysis of a Competing Portfolio Market with a Polyvariant Profit Function

    Bogolubov, Nikolai N. Jr.; Kyshakevych, Bohdan Yu.; Blackmore, Denis; Prykarpatsky, Anatoliy K.

    2010-12-01

    A competing market model with a polyvariant profit function that assumes 'zeitnot' stock behavior of clients is formulated within the banking portfolio medium and then analyzed from the perspective of devising optimal strategies. An associated Markov process method for finding an optimal choice strategy for monovariant and bivariant profit functions is developed. Under certain conditions on the bank 'promotional' parameter with respect to the 'fee' for a missed share package transaction and at an asymptotically large enough portfolio volume, universal transcendental equations - determining the optimal share package choice among competing strategies with monovariant and bivariant profit functions - are obtained. (author)

  13. Conference on "State of the Art in Global Optimization : Computational Methods and Applications"

    Pardalos, P

    1996-01-01

    Optimization problems abound in most fields of science, engineering, and technology. In many of these problems it is necessary to compute the global optimum (or a good approximation) of a multivariable function. The variables that define the function to be optimized can be continuous and/or discrete and, in addition, many times satisfy certain constraints. Global optimization problems belong to the complexity class of NP-hard prob­ lems. Such problems are very difficult to solve. Traditional descent optimization algorithms based on local information are not adequate for solving these problems. In most cases of practical interest the number of local optima increases, on the aver­ age, exponentially with the size of the problem (number of variables). Furthermore, most of the traditional approaches fail to escape from a local optimum in order to continue the search for the global solution. Global optimization has received a lot of attention in the past ten years, due to the success of new algorithms for solvin...

  14. Global warming and carbon taxation. Optimal policy and the role of administration costs

    Williams, M.

    1995-01-01

    This paper develops a model relating CO 2 emissions to atmosphere concentrations, global temperature change and economic damages. For a variety of parameter assumptions, the model provides estimates of the marginal cost of emissions in various years. The optimal carbon tax is a function of the marginal emission cost and the costs of administering the tax. This paper demonstrates that under any reasonable assumptions, the optimal carbon tax is zero for at least several decades. (author)

  15. Application of evolution strategy algorithm for optimization of a single-layer sound absorber

    Morteza Gholamipoor

    2014-12-01

    Full Text Available Depending on different design parameters and limitations, optimization of sound absorbers has always been a challenge in the field of acoustic engineering. Various methods of optimization have evolved in the past decades with innovative method of evolution strategy gaining more attention in the recent years. Based on their simplicity and straightforward mathematical representations, single-layer absorbers have been widely used in both engineering and industrial applications and an optimized design for these absorbers has become vital. In the present study, the method of evolution strategy algorithm is used for optimization of a single-layer absorber at both a particular frequency and an arbitrary frequency band. Results of the optimization have been compared against different methods of genetic algorithm and penalty functions which are proved to be favorable in both effectiveness and accuracy. Finally, a single-layer absorber is optimized in a desired range of frequencies that is the main goal of an industrial and engineering optimization process.

  16. Optimizing Quality of Care and Patient Safety in Malaysia: The Current Global Initiatives, Gaps and Suggested Solutions.

    Jarrar, Mu'taman; Abdul Rahman, Hamzah; Don, Mohammad Sobri

    2015-10-20

    Demand for health care service has significantly increased, while the quality of healthcare and patient safety has become national and international priorities. This paper aims to identify the gaps and the current initiatives for optimizing the quality of care and patient safety in Malaysia. Review of the current literature. Highly cited articles were used as the basis to retrieve and review the current initiatives for optimizing the quality of care and patient safety. The country health plan of Ministry of Health (MOH) Malaysia and the MOH Malaysia Annual Reports were reviewed. The MOH has set four strategies for optimizing quality and sustaining quality of life. The 10th Malaysia Health Plan promotes the theme "1 Care for 1 Malaysia" in order to sustain the quality of care. Despite of these efforts, the total number of complaints received by the medico-legal section of the MOH Malaysia is increasing. The current global initiatives indicted that quality performance generally belong to three main categories: patient; staffing; and working environment related factors. There is no single intervention for optimizing quality of care to maintain patient safety. Multidimensional efforts and interventions are recommended in order to optimize the quality of care and patient safety in Malaysia.

  17. Optimizing Quality of Care and Patient Safety in Malaysia: The Current Global Initiatives, Gaps and Suggested Solutions

    Jarrar, Mu’taman; Rahman, Hamzah Abdul; Don, Mohammad Sobri

    2016-01-01

    Background and Objective: Demand for health care service has significantly increased, while the quality of healthcare and patient safety has become national and international priorities. This paper aims to identify the gaps and the current initiatives for optimizing the quality of care and patient safety in Malaysia. Design: Review of the current literature. Highly cited articles were used as the basis to retrieve and review the current initiatives for optimizing the quality of care and patient safety. The country health plan of Ministry of Health (MOH) Malaysia and the MOH Malaysia Annual Reports were reviewed. Results: The MOH has set four strategies for optimizing quality and sustaining quality of life. The 10th Malaysia Health Plan promotes the theme “1 Care for 1 Malaysia” in order to sustain the quality of care. Despite of these efforts, the total number of complaints received by the medico-legal section of the MOH Malaysia is increasing. The current global initiatives indicted that quality performance generally belong to three main categories: patient; staffing; and working environment related factors. Conclusions: There is no single intervention for optimizing quality of care to maintain patient safety. Multidimensional efforts and interventions are recommended in order to optimize the quality of care and patient safety in Malaysia. PMID:26755459

  18. Scout or Cavalry? Optimal Discovery Strategies for GRBs

    Nemiroff, Robert J.

    2004-01-01

    Many present and past gamma-ray burst (GRB) detectors try to be not only a 'scout', discovering new GRBs, but also the 'cavalry', simultaneously optimizing on-board science return. Recently, however, most GRB science return has moved out from the gamma-ray energy bands where discovery usually occurs. Therefore a future gamma-ray instrument that is only a scout might best optimize future GRB science. Such a scout would specialize solely in the initial discovery of GRBs, determining only those properties that would allow an unambiguous handoff to waiting cavalry instruments. Preliminary general principles of scout design and cadence are discussed. Scouts could implement observing algorithms optimized for finding GRBs with specific attributes of duration, location, or energy. Scout sky-scanning algorithms utilizing a return cadence near to desired durations of short GRBs are suggested as a method of discovering GRBs in the unexplored short duration part of the GRB duration distribution

  19. Investment Strategies Optimization based on a SAX-GA Methodology

    Canelas, António M L; Horta, Nuno C G

    2013-01-01

    This book presents a new computational finance approach combining a Symbolic Aggregate approXimation (SAX) technique with an optimization kernel based on genetic algorithms (GA). While the SAX representation is used to describe the financial time series, the evolutionary optimization kernel is used in order to identify the most relevant patterns and generate investment rules. The proposed approach considers several different chromosomes structures in order to achieve better results on the trading platform The methodology presented in this book has great potential on investment markets.

  20. The EU's New Global Strategy : Its Implementation in a Troubled International Environment

    Buitelaar, T.; Larik, J.E.; Matta, A.; Vos, de B.

    2016-01-01

    Executive Summary In June 2016, High Representative Mogherini presented the EU’s new Global Strategy on Foreign and Security Policy (EUGS) to the European Council. With the Strategy now finalized, attention needs to turn to its implementation in an environment mired by crises both within Europe and

  1. Corporate Strategies and Global Competition: Odense Steel Shipyard, 1918-2012

    Poulsen, Rene Taudal; Jensen, Kristoffer; Christensen, Rene Schroder

    2017-01-01

    This article analyzes the competitive strategies of Odense Steel Shipyard between 1918 and 2012 and challenges existing scholarship on competition in global industries. Until the 1980s, the yard adopted typical strategies in shipbuilding, starting with cost leadership and subsequently adopting...

  2. Analyzing “Etka Chain Stores” Strategies and Proposing Optimal Strategies; Using SWOT Model based on Fuzzy Logic

    Mohammad Aghaei; Amin Asadollahi; Elham Vahedi; Mahdi Pirooz

    2013-01-01

    To maintain and achieve optimal growth, development and to be more competitive, organizations need a comprehensive and coherent plan compatible with their objectives and goals which is called strategic planning. This research aims to analyse strategically “Etka Chain Stores” and to propose optimal strategies by using SWOT model and based on fuzzy logic. The scope of this research is limited to “Etka Chain stores in Tehran”. As instrumentation, a questioner, consisting of 138 questions, was us...

  3. Cooperative Coevolution with Formula-Based Variable Grouping for Large-Scale Global Optimization.

    Wang, Yuping; Liu, Haiyan; Wei, Fei; Zong, Tingting; Li, Xiaodong

    2017-08-09

    For a large-scale global optimization (LSGO) problem, divide-and-conquer is usually considered an effective strategy to decompose the problem into smaller subproblems, each of which can then be solved individually. Among these decomposition methods, variable grouping is shown to be promising in recent years. Existing variable grouping methods usually assume the problem to be black-box (i.e., assuming that an analytical model of the objective function is unknown), and they attempt to learn appropriate variable grouping that would allow for a better decomposition of the problem. In such cases, these variable grouping methods do not make a direct use of the formula of the objective function. However, it can be argued that many real-world problems are white-box problems, that is, the formulas of objective functions are often known a priori. These formulas of the objective functions provide rich information which can then be used to design an effective variable group method. In this article, a formula-based grouping strategy (FBG) for white-box problems is first proposed. It groups variables directly via the formula of an objective function which usually consists of a finite number of operations (i.e., four arithmetic operations "[Formula: see text]", "[Formula: see text]", "[Formula: see text]", "[Formula: see text]" and composite operations of basic elementary functions). In FBG, the operations are classified into two classes: one resulting in nonseparable variables, and the other resulting in separable variables. In FBG, variables can be automatically grouped into a suitable number of non-interacting subcomponents, with variables in each subcomponent being interdependent. FBG can easily be applied to any white-box problem and can be integrated into a cooperative coevolution framework. Based on FBG, a novel cooperative coevolution algorithm with formula-based variable grouping (so-called CCF) is proposed in this article for decomposing a large-scale white-box problem

  4. Optimizing torque vectoring strategies for an electric vehicle concept

    van Boekel, J.J.P.; Besselink, I.J.M.; Nijmeijer, H.; Rauh, J.; Knorr, S.; Durnberger, J.

    2013-01-01

    As part of the internship project carried out at Daimler AG, this report describes the application and optimization of torque vectoring on a research vehicle based on the Mercedes- Benz SLS AMG E-CELL. A concise introduction is given regarding the MATLAB scripts and Simulink models that were used

  5. Taxing Strategies for Carbon Emissions: A Bilevel Optimization Approach

    Wei Wei

    2014-04-01

    Full Text Available This paper presents a quantitative and computational method to determine the optimal tax rate among generating units. To strike a balance between the reduction of carbon emission and the profit of energy sectors, the proposed bilevel optimization model can be regarded as a Stackelberg game between the government agency and the generation companies. The upper-level, which represents the government agency, aims to limit total carbon emissions within a certain level by setting optimal tax rates among generators according to their emission performances. The lower-level, which represents decision behaviors of the grid operator, tries to minimize the total production cost under the tax rates set by the government. The bilevel optimization model is finally reformulated into a mixed integer linear program (MILP which can be solved by off-the-shelf MILP solvers. Case studies on a 10-unit system as well as a provincial power grid in China demonstrate the validity of the proposed method and its capability in practical applications.

  6. An Optimal Stochastic Investment and Consumption Strategy with ...

    This paper considers a single investor who owns a production plant that generates units of consumption goods in a capitalist economy. The goal is to choose optimal investment and consumption policies that maximize the finite horizon expected discounted logarithmic utility of consumption and terminal wealth. A dynamical ...

  7. Optimal detection and control strategies for invasive species management

    Shefali V. Mehta; Robert G. Haight; Frances R. Homans; Stephen Polasky; Robert C. Venette

    2007-01-01

    The increasing economic and environmental losses caused by non-native invasive species amplify the value of identifying and implementing optimal management options to prevent, detect, and control invasive species. Previous literature has focused largely on preventing introductions of invasive species and post-detection control activities; few have addressed the role of...

  8. Theoretical properties of the global optimizer of two layer neural network

    Boob, Digvijay; Lan, Guanghui

    2017-01-01

    In this paper, we study the problem of optimizing a two-layer artificial neural network that best fits a training dataset. We look at this problem in the setting where the number of parameters is greater than the number of sampled points. We show that for a wide class of differentiable activation functions (this class involves "almost" all functions which are not piecewise linear), we have that first-order optimal solutions satisfy global optimality provided the hidden layer is non-singular. ...

  9. Climate, Agriculture, Energy and the Optimal Allocation of Global Land Use

    Steinbuks, J.; Hertel, T. W.

    2011-12-01

    The allocation of the world's land resources over the course of the next century has become a pressing research question. Continuing population increases, improving, land-intensive diets amongst the poorest populations in the world, increasing production of biofuels and rapid urbanization in developing countries are all competing for land even as the world looks to land resources to supply more environmental services. The latter include biodiversity and natural lands, as well as forests and grasslands devoted to carbon sequestration. And all of this is taking place in the context of faster than expected climate change which is altering the biophysical environment for land-related activities. The goal of the paper is to determine the optimal profile for global land use in the context of growing commercial demands for food and forest products, increasing non-market demands for ecosystem services, and more stringent GHG mitigation targets. We then seek to assess how the uncertainty associated with the underlying biophysical and economic processes influences this optimal profile of land use, in light of potential irreversibility in these decisions. We develop a dynamic long-run, forward-looking partial equilibrium framework in which the societal objective function being maximized places value on food production, liquid fuels (including biofuels), timber production, forest carbon and biodiversity. Given the importance of land-based emissions to any GHG mitigation strategy, as well as the potential impacts of climate change itself on the productivity of land in agriculture, forestry and ecosystem services, we aim to identify the optimal allocation of the world's land resources, over the course of the next century, in the face of alternative GHG constraints. The forestry sector is characterized by multiple forest vintages which add considerable computational complexity in the context of this dynamic analysis. In order to solve this model efficiently, we have employed the

  10. Remote sensing strategies for global resource exploration and environmental management

    Henderson, Frederick B.

    Since 1972, satellite remote sensing, when integrated with other exploration techniques, has demonstrated operational exploration and engineering cost savings and reduced exploration risks through improved geological mapping. Land and ocean remote sensing satellite systems under development for the 1990's by the United States, France, Japan, Canada, ESA, Russia, China, and others, will significantly increase our ability to explore for, develop, and manage energy and mineral resources worldwide. A major difference between these systems is the "Open Skies" and "Non-Discriminatory Access to Data" policies as have been practiced by the U.S. and France and the restrictive nationalistic data policies as have been practiced by Russia and India. Global exploration will use satellite remote sensing to better map regional structural and basin-like features that control the distribution of energy and mineral resources. Improved sensors will better map lithologic and stratigraphic units and identify alteration effects in rocks, soils, and vegetation cover indicative of undiscovered subsurface resources. These same sensors will also map and monitor resource development. The use of satellite remote sensing data will grow substantially through increasing integration with other geophysical, geochemical, and geologic data using improved geographic information systems (GIS). International exploration will focus on underdeveloped countries rather than on mature exploration areas such as the United States, Europe, and Japan. Energy and mineral companies and government agencies in these countries and others will utilize available remote sensing data to acquire economic intelligence on global resources. If the "Non-Discriminatory Access to Data" principle is observed by satellite producing countries, exploration will remain competitive "on the ground". In this manner, remote sensing technology will continue to be developed to better explore for and manage the world's needed resources

  11. Investigating the Optimal Management Strategy for a Healthcare Facility Maintenance Program

    Gaillard, Daria

    2004-01-01

    ...: strategic partnering with an equipment management firm. The objective of this study is to create a decision-model for selecting the optimal management strategy for a healthcare organization's facility maintenance program...

  12. A global optimization algorithm inspired in the behavior of selfish herds.

    Fausto, Fernando; Cuevas, Erik; Valdivia, Arturo; González, Adrián

    2017-10-01

    In this paper, a novel swarm optimization algorithm called the Selfish Herd Optimizer (SHO) is proposed for solving global optimization problems. SHO is based on the simulation of the widely observed selfish herd behavior manifested by individuals within a herd of animals subjected to some form of predation risk. In SHO, individuals emulate the predatory interactions between groups of prey and predators by two types of search agents: the members of a selfish herd (the prey) and a pack of hungry predators. Depending on their classification as either a prey or a predator, each individual is conducted by a set of unique evolutionary operators inspired by such prey-predator relationship. These unique traits allow SHO to improve the balance between exploration and exploitation without altering the population size. To illustrate the proficiency and robustness of the proposed method, it is compared to other well-known evolutionary optimization approaches such as Particle Swarm Optimization (PSO), Artificial Bee Colony (ABC), Firefly Algorithm (FA), Differential Evolution (DE), Genetic Algorithms (GA), Crow Search Algorithm (CSA), Dragonfly Algorithm (DA), Moth-flame Optimization Algorithm (MOA) and Sine Cosine Algorithm (SCA). The comparison examines several standard benchmark functions, commonly considered within the literature of evolutionary algorithms. The experimental results show the remarkable performance of our proposed approach against those of the other compared methods, and as such SHO is proven to be an excellent alternative to solve global optimization problems. Copyright © 2017 Elsevier B.V. All rights reserved.

  13. Global optimal path planning of an autonomous vehicle for overtaking a moving obstacle

    B. Mashadi

    Full Text Available In this paper, the global optimal path planning of an autonomous vehicle for overtaking a moving obstacle is proposed. In this study, the autonomous vehicle overtakes a moving vehicle by performing a double lane-change maneuver after detecting it in a proper distance ahead. The optimal path of vehicle for performing the lane-change maneuver is generated by a path planning program in which the sum of lateral deviation of the vehicle from a reference path and the rate of steering angle become minimum while the lateral acceleration of vehicle does not exceed a safe limit value. A nonlinear optimal control theory with the lateral vehicle dynamics equations and inequality constraint of lateral acceleration are used to generate the path. The indirect approach for solving the optimal control problem is used by applying the calculus of variation and the Pontryagin's Minimum Principle to obtain first-order necessary conditions for optimality. The optimal path is generated as a global optimal solution and can be used as the benchmark of the path generated by the local motion planning of autonomous vehicles. A full nonlinear vehicle model in CarSim software is used for path following simulation by importing path data from the MATLAB code. The simulation results show that the generated path for the autonomous vehicle satisfies all vehicle dynamics constraints and hence is a suitable overtaking path for the following vehicle.

  14. An advanced Lithium-ion battery optimal charging strategy based on a coupled thermoelectric model

    Liu, Kailong; Li, Kang; Yang, Zhile; Zhang, Cheng; Deng, Jing

    2017-01-01

    Lithium-ion batteries are widely adopted as the power supplies for electric vehicles. A key but challenging issue is to achieve optimal battery charging, while taking into account of various constraints for safe, efficient and reliable operation. In this paper, a triple-objective function is first formulated for battery charging based on a coupled thermoelectric model. An advanced optimal charging strategy is then proposed to develop the optimal constant-current-constant-voltage (CCCV) charge current profile, which gives the best trade-off among three conflicting but important objectives for battery management. To be specific, a coupled thermoelectric battery model is first presented. Then, a specific triple-objective function consisting of three objectives, namely charging time, energy loss, and temperature rise (both the interior and surface), is proposed. Heuristic methods such as Teaching-learning-based-optimization (TLBO) and particle swarm optimization (PSO) are applied to optimize the triple-objective function, and their optimization performances are compared. The impacts of the weights for different terms in the objective function are then assessed. Experimental results show that the proposed optimal charging strategy is capable of offering desirable effective optimal charging current profiles and a proper trade-off among the conflicting objectives. Further, the proposed optimal charging strategy can be easily extended to other battery types.

  15. Mean-variance Optimal Reinsurance-investment Strategy in Continuous Time

    Daheng Peng

    2017-10-01

    Full Text Available In this paper, Lagrange method is used to solve the continuous-time mean-variance reinsurance-investment problem. Proportional reinsurance, multiple risky assets and risk-free asset are considered synthetically in the optimal strategy for insurers. By solving the backward stochastic differential equation for the Lagrange multiplier, we get the mean-variance optimal reinsurance-investment strategy and its effective frontier in explicit forms.

  16. Optimization of control strategies for epidemics in heterogeneous populations with symmetric and asymmetric transmission

    Ndeffo Mbah , Martial L.; Gilligan , Christopher A.

    2010-01-01

    Abstract There is growing interest in incorporating economic factors into epidemiological models in order to identify optimal strategies for disease control when resources are limited. In this paper we consider how to optimize the control of a pathogen that is capable of infecting multiple hosts with different rates of transmission within and between species. Our objective is to find control strategies that maximize the discounted number of healthy individuals. We consider two clas...

  17. Optimal Control Strategies in a Two Dimensional Differential Game Using Linear Equation under a Perturbed System

    Musa Danjuma SHEHU

    2008-06-01

    Full Text Available This paper lays emphasis on formulation of two dimensional differential games via optimal control theory and consideration of control systems whose dynamics is described by a system of Ordinary Differential equation in the form of linear equation under the influence of two controls U(. and V(.. Base on this, strategies were constructed. Hence we determine the optimal strategy for a control say U(. under a perturbation generated by the second control V(. within a given manifold M.

  18. The CEV Model and Its Application in a Study of Optimal Investment Strategy

    Aiyin Wang

    2014-01-01

    Full Text Available The constant elasticity of variance (CEV model is used to describe the price of the risky asset. Maximizing the expected utility relating to the Hamilton-Jacobi-Bellman (HJB equation which describes the optimal investment strategies, we obtain a partial differential equation. Applying the Legendre transform, we transform the equation into a dual problem and obtain an approximation solution and an optimal investment strategies for the exponential utility function.

  19. Mean-variance Optimal Reinsurance-investment Strategy in Continuous Time

    Daheng Peng; Fang Zhang

    2017-01-01

    In this paper, Lagrange method is used to solve the continuous-time mean-variance reinsurance-investment problem. Proportional reinsurance, multiple risky assets and risk-free asset are considered synthetically in the optimal strategy for insurers. By solving the backward stochastic differential equation for the Lagrange multiplier, we get the mean-variance optimal reinsurance-investment strategy and its effective frontier in explicit forms.

  20. Optimized Control Strategy For Over Loaded Offshore Wind Turbines

    Odgaard, Peter Fogh; Knudsen, Torben; Wisniewski, Rafal

    2015-01-01

    controller tuning for a given wind turbine. It also enables a very safe and robust comparison between a new control strategy and the present one. Main body of abstract Is it true that power de-rating indeed the best way to reduce loads? The power de-rating approach has the drawback of only indirectly...

  1. Simulated Stochastic Approximation Annealing for Global Optimization With a Square-Root Cooling Schedule

    Liang, Faming; Cheng, Yichen; Lin, Guang

    2014-01-01

    cooling schedule, for example, a square-root cooling schedule, while guaranteeing the global optima to be reached when the temperature tends to zero. The new algorithm has been tested on a few benchmark optimization problems, including feed-forward neural

  2. Optimizing social participation in community-dwelling older adults through the use of behavioral coping strategies.

    Provencher, Véronique; Desrosiers, Johanne; Demers, Louise; Carmichael, Pierre-Hugues

    2016-01-01

    This study aimed to (1) determine the categories of behavioral coping strategies most strongly correlated with optimal seniors' social participation in different activity and role domains and (2) identify the demographic, health and environmental factors associated with the use of these coping strategies optimizing social participation. The sample consisted of 350 randomly recruited community-dwelling older adults (≥65 years). Coping strategies and social participation were measured, respectively, using the Inventory of Coping Strategies Used by the Elderly and Assessment of Life Habits questionnaires. Information about demographic, health and environmental factors was also collected during the interview. Regression analyses showed a strong relationship between the use of cooking- and transportation-related coping strategies and optimal participation in the domains of nutrition and community life, respectively. Older age and living alone were associated with increased use of cooking-related strategies, while good self-rated health and not living in a seniors' residence were correlated with greater use of transportation-related strategies. Our study helped to identify useful behavioral coping strategies that should be incorporated in disability prevention programs designed to promote community-dwelling seniors' social participation. However, the appropriateness of these strategies depends on whether they are used in relevant contexts and tailored to specific needs. Our results support the relevance of including behavioral coping strategies related to cooking and transportation in disability prevention programs designed to promote community-dwelling seniors' social participation in the domains of nutrition and community life, respectively. Older age and living alone were associated with increased use of cooking-related strategies, while good self-rated health and not living in a seniors' residence were correlated with greater use of transportation

  3. Energy and the environment. A global view and strategies

    Pasztor, J.

    1988-01-01

    It should be recognized that the key to the future is in the rational use of energy, that is, a more efficient use of energy rather than a continuous increase in the supply of energy. Every unit of energy saved is a unit of energy which does not have to be produced, and whose environmental impacts do not have to be dealt with. Massive reductions in the growth rates, and, where possible, in the absolute use of energy will help us to gain time to better understand and develop response strategies to problems like climate change on the acidification of the environment. In this sense the rational use of energy, including intensified energy efficiency measures is the most environmentally sound energy option with which we should move into the next century. 25 refs., 4 figs

  4. Maintenance and test strategies to optimize NPP equipment performance

    Mayer, S.; Tomic, B.

    2000-01-01

    This paper proposes an approach to maintenance optimization of nuclear power plant components, which can help to increase both safety and availability. In order to evaluate the benefits of preventive maintenance on a quantitative basis, a software code has been developed for component performance and reliability simulation of safety related nuclear power plant equipment. A three state Markov model will be introduced, considering a degraded state in addition to an operational state and a failed state. (author)

  5. Optimal Input Strategy for Plug and Play Process Control Systems

    Kragelund, Martin Nygaard; Leth, John-Josef; Wisniewski, Rafal

    2010-01-01

    This paper considers the problem of optimal operation of a plant, which goal is to maintain production at minimum cost. The system considered in this work consists of a joined plant and redundant input systems. It is assumed that each input system contributes to a flow of goods into the joined pa...... the performance of the plant. The results are applied to a coal fired power plant where an additional new fuel system, gas, becomes available....

  6. Systems analysis as a tool for optimal process strategy

    Ditterich, K.; Schneider, J.

    1975-09-01

    For the description and the optimal treatment of complex processes, the methods of Systems Analysis are used as the most promising approach in recent times. In general every process should be optimised with respect to reliability, safety, economy and environmental pollution. In this paper the complex relations between these general optimisation postulates are established in qualitative form. These general trend relations have to be quantified for every particular system studied in practice

  7. Optimal Quality Strategy and Matching Service on Crowdfunding Platforms

    Wenqing Wu

    2018-04-01

    Full Text Available This paper develops a crowdfunding platform model incorporating quality and a matching service from the perspective of a two-sided market. It aims to explore the impact of different factors on the optimal quality threshold and matching service in a context of crowdfunding from the perspective of a two-sided market. We discuss the impact of different factors on the optimal quality threshold and matching service. Two important influential factors are under consideration, simultaneously. One is the quality threshold of admission and the other is the matching efficiency on crowdfunding platforms. This paper develops a two-sided market model incorporating quality, a matching service, and the characters of crowdfunding campaigns. After attempting to solve the model by derivative method, this paper identifies the mechanism of how the parameters influence the optimal quality threshold and matching service. Additionally, it compares the platform profits in scenarios with and without an exclusion policy. The results demonstrate that excluding low-quality projects is profitable when funder preference for project quality is substantial enough. Crowdfunding platform managers would be unwise to admit the quality threshold of the crowdfunding project and charge entrance fees when the parameter of funder preference for project quality is small.

  8. PS-FW: A Hybrid Algorithm Based on Particle Swarm and Fireworks for Global Optimization

    Chen, Shuangqing; Wei, Lixin; Guan, Bing

    2018-01-01

    Particle swarm optimization (PSO) and fireworks algorithm (FWA) are two recently developed optimization methods which have been applied in various areas due to their simplicity and efficiency. However, when being applied to high-dimensional optimization problems, PSO algorithm may be trapped in the local optima owing to the lack of powerful global exploration capability, and fireworks algorithm is difficult to converge in some cases because of its relatively low local exploitation efficiency for noncore fireworks. In this paper, a hybrid algorithm called PS-FW is presented, in which the modified operators of FWA are embedded into the solving process of PSO. In the iteration process, the abandonment and supplement mechanism is adopted to balance the exploration and exploitation ability of PS-FW, and the modified explosion operator and the novel mutation operator are proposed to speed up the global convergence and to avoid prematurity. To verify the performance of the proposed PS-FW algorithm, 22 high-dimensional benchmark functions have been employed, and it is compared with PSO, FWA, stdPSO, CPSO, CLPSO, FIPS, Frankenstein, and ALWPSO algorithms. Results show that the PS-FW algorithm is an efficient, robust, and fast converging optimization method for solving global optimization problems. PMID:29675036

  9. Strategies for antiviral stockpiling for future influenza pandemics: a global epidemic-economic perspective.

    Carrasco, Luis R; Lee, Vernon J; Chen, Mark I; Matchar, David B; Thompson, James P; Cook, Alex R

    2011-09-07

    Influenza pandemics present a global threat owing to their potential mortality and substantial economic impacts. Stockpiling antiviral drugs to manage a pandemic is an effective strategy to offset their negative impacts; however, little is known about the long-term optimal size of the stockpile under uncertainty and the characteristics of different countries. Using an epidemic-economic model we studied the effect on total mortality and costs of antiviral stockpile sizes for Brazil, China, Guatemala, India, Indonesia, New Zealand, Singapore, the UK, the USA and Zimbabwe. In the model, antivirals stockpiling considerably reduced mortality. There was greater potential avoidance of expected costs in the higher resourced countries (e.g. from $55 billion to $27 billion over a 30 year time horizon for the USA) and large avoidance of fatalities in those less resourced (e.g. from 11.4 to 2.3 million in Indonesia). Under perfect allocation, higher resourced countries should aim to store antiviral stockpiles able to cover at least 15 per cent of their population, rising to 25 per cent with 30 per cent misallocation, to minimize fatalities and economic costs. Stockpiling is estimated not to be cost-effective for two-thirds of the world's population under current antivirals pricing. Lower prices and international cooperation are necessary to make the life-saving potential of antivirals cost-effective in resource-limited countries.

  10. Top-down constraints on global N2O emissions at optimal resolution: application of a new dimension reduction technique

    Wells, Kelley C.; Millet, Dylan B.; Bousserez, Nicolas; Henze, Daven K.; Griffis, Timothy J.; Chaliyakunnel, Sreelekha; Dlugokencky, Edward J.; Saikawa, Eri; Xiang, Gao; Prinn, Ronald G.; O'Doherty, Simon; Young, Dickon; Weiss, Ray F.; Dutton, Geoff S.; Elkins, James W.; Krummel, Paul B.; Langenfelds, Ray; Steele, L. Paul

    2018-01-01

    We present top-down constraints on global monthly N2O emissions for 2011 from a multi-inversion approach and an ensemble of surface observations. The inversions employ the GEOS-Chem adjoint and an array of aggregation strategies to test how well current observations can constrain the spatial distribution of global N2O emissions. The strategies include (1) a standard 4D-Var inversion at native model resolution (4° × 5°), (2) an inversion for six continental and three ocean regions, and (3) a fast 4D-Var inversion based on a novel dimension reduction technique employing randomized singular value decomposition (SVD). The optimized global flux ranges from 15.9 Tg N yr-1 (SVD-based inversion) to 17.5-17.7 Tg N yr-1 (continental-scale, standard 4D-Var inversions), with the former better capturing the extratropical N2O background measured during the HIAPER Pole-to-Pole Observations (HIPPO) airborne campaigns. We find that the tropics provide a greater contribution to the global N2O flux than is predicted by the prior bottom-up inventories, likely due to underestimated agricultural and oceanic emissions. We infer an overestimate of natural soil emissions in the extratropics and find that predicted emissions are seasonally biased in northern midlatitudes. Here, optimized fluxes exhibit a springtime peak consistent with the timing of spring fertilizer and manure application, soil thawing, and elevated soil moisture. Finally, the inversions reveal a major emission underestimate in the US Corn Belt in the bottom-up inventory used here. We extensively test the impact of initial conditions on the analysis and recommend formally optimizing the initial N2O distribution to avoid biasing the inferred fluxes. We find that the SVD-based approach provides a powerful framework for deriving emission information from N2O observations: by defining the optimal resolution of the solution based on the information content of the inversion, it provides spatial information that is lost when

  11. A universal optimization strategy for ant colony optimization algorithms based on the Physarum-inspired mathematical model

    Zhang, Zili; Gao, Chao; Liu, Yuxin; Qian, Tao

    2014-01-01

    Ant colony optimization (ACO) algorithms often fall into the local optimal solution and have lower search efficiency for solving the travelling salesman problem (TSP). According to these shortcomings, this paper proposes a universal optimization strategy for updating the pheromone matrix in the ACO algorithms. The new optimization strategy takes advantages of the unique feature of critical paths reserved in the process of evolving adaptive networks of the Physarum-inspired mathematical model (PMM). The optimized algorithms, denoted as PMACO algorithms, can enhance the amount of pheromone in the critical paths and promote the exploitation of the optimal solution. Experimental results in synthetic and real networks show that the PMACO algorithms are more efficient and robust than the traditional ACO algorithms, which are adaptable to solve the TSP with single or multiple objectives. Meanwhile, we further analyse the influence of parameters on the performance of the PMACO algorithms. Based on these analyses, the best values of these parameters are worked out for the TSP. (paper)

  12. Workshop Builds Strategies to Address Global Positioning System Vulnerabilities

    Fisher, Genene

    2011-01-01

    When we examine the impacts of space weather on society, do we really understand the risks? Can past experiences reliably predict what will happen in the future? As the complexity of technology increases, there is the potential for it to become more fragile, allowing for a single point of failure to bring down the entire system. Take the Global Positioning System (GPS) as an example. GPS positioning, navigation, and timing have become an integral part of daily life, supporting transportation and communications systems vital to the aviation, merchant marine, cargo, cellular phone, surveying, and oil exploration industries. Everyday activities such as banking, mobile phone operations, and even the control of power grids are facilitated by the accurate timing provided by GPS. Understanding the risks of space weather to GPS and the many economic sectors reliant upon it, as well as how to build resilience, was the focus of a policy workshop organized by the American Meteorological Society (AMS) and held on 13-14 October 2010 in Washington, D. C. The workshop brought together a select group of policy makers, space weather scientists, and GPS experts and users.

  13. Global approaches and local strategies for phase unwrapping

    Guerriero, L.; Refice, A.; Stramaglia, S.; Chiaradia, M. T.; Satalino, G.; Veneziani, N.; Blonda, P.; Pasquariello, G.

    2001-01-01

    Phase unwrapping, i.e. the retrieval of absolute phases from wrapped, noisy measures, is a tough problem because of the presence of rotational inconsistencies (residues), randomly generated by noise and undersampling on the principal phase gradient field. These inconsistencies prevent the recovery of the absolute phase field by direct integration of the wrapped gradients. In this paper it is examined the relative merit of known global approaches and then it is presented evidence that the approach based on stochastic annealing can recover the true phase field also in noisy areas with severe undersampling, where other methods fail. Then, some experiments with local approaches are presented. A fast neural filter has been trained to eliminate close residue couples by joining them in a way which takes into account the local phase information. Performances are about 60-70% of the residues. Finally, other experiments have been aimed at designing an automated method for the determination of weight matrices to use in conjunction with local phase unwrapping algorithms. The method, tested with the minimum cost flow algorithm, gives good performances over both simulated and real data

  14. Multiresolution strategies for the numerical solution of optimal control problems

    Jain, Sachin

    There exist many numerical techniques for solving optimal control problems but less work has been done in the field of making these algorithms run faster and more robustly. The main motivation of this work is to solve optimal control problems accurately in a fast and efficient way. Optimal control problems are often characterized by discontinuities or switchings in the control variables. One way of accurately capturing the irregularities in the solution is to use a high resolution (dense) uniform grid. This requires a large amount of computational resources both in terms of CPU time and memory. Hence, in order to accurately capture any irregularities in the solution using a few computational resources, one can refine the mesh locally in the region close to an irregularity instead of refining the mesh uniformly over the whole domain. Therefore, a novel multiresolution scheme for data compression has been designed which is shown to outperform similar data compression schemes. Specifically, we have shown that the proposed approach results in fewer grid points in the grid compared to a common multiresolution data compression scheme. The validity of the proposed mesh refinement algorithm has been verified by solving several challenging initial-boundary value problems for evolution equations in 1D. The examples have demonstrated the stability and robustness of the proposed algorithm. The algorithm adapted dynamically to any existing or emerging irregularities in the solution by automatically allocating more grid points to the region where the solution exhibited sharp features and fewer points to the region where the solution was smooth. Thereby, the computational time and memory usage has been reduced significantly, while maintaining an accuracy equivalent to the one obtained using a fine uniform mesh. Next, a direct multiresolution-based approach for solving trajectory optimization problems is developed. The original optimal control problem is transcribed into a

  15. A two-level strategy to realize life-cycle production optimization in an operational setting

    Essen, van G.M.; Hof, Van den P.M.J.; Jansen, J.D.

    2012-01-01

    We present a two-level strategy to improve robustness against uncertainty and model errors in life-cycle flooding optimization. At the upper level, a physics-based large-scale reservoir model is used to determine optimal life-cycle injection and production profiles. At the lower level these profiles

  16. A two-level strategy to realize life-cycle production optimization in an operational setting

    Essen, van G.M.; Hof, Van den P.M.J.; Jansen, J.D.

    2013-01-01

    We present a two-level strategy to improve robustness against uncertainty and model errors in life-cycle flooding optimization. At the upper level, a physics-based large-scale reservoir model is used to determine optimal life-cycle injection and production profiles. At the lower level these profiles

  17. Global optimization based on noisy evaluations: An empirical study of two statistical approaches

    Vazquez, Emmanuel; Villemonteix, Julien; Sidorkiewicz, Maryan; Walter, Eric

    2008-01-01

    The optimization of the output of complex computer codes has often to be achieved with a small budget of evaluations. Algorithms dedicated to such problems have been developed and compared, such as the Expected Improvement algorithm (El) or the Informational Approach to Global Optimization (IAGO). However, the influence of noisy evaluation results on the outcome of these comparisons has often been neglected, despite its frequent appearance in industrial problems. In this paper, empirical convergence rates for El and IAGO are compared when an additive noise corrupts the result of an evaluation. IAGO appears more efficient than El and various modifications of El designed to deal with noisy evaluations. Keywords. Global optimization; computer simulations; kriging; Gaussian process; noisy evaluations.

  18. WHAT FIRMS ARE REWARDED AFTER GLOBAL FINANCIAL CRISIS? THE ROLE OF INNOVATION AND GLOBALIZATION STRATEGIES IN RECOVERY

    Victoria Golikova

    2016-03-01

    Full Text Available The aim of the research is to conduct an empirical investigation and reveal what types of globalization and innovation strategies in turbulent and unfavorable regional institutional environment are most likely to be associated with different trajectories of Russian manufacturing firms’ performance in 2007- 2012. We employ the results of empirical survey of 1000 medium and large enterprises in manufacturing (2009 linked to financial data from Amadeus database and the data on the regional institutional environment. We test that (1 introduction of innovations before the crisis ceteris paribus helped the firms to successfully pass the crisis and recover. We expect that (2 companies that became globalized before the crisis (via importing of intermediate and capital goods; exporting; FDI; establishment of partner linkages with foreign firms ceteris paribus are more likely to successfully pass the crisis and grow. And (3 propose the positive effect of synergy of innovation efforts and globalization strategy of the firm. We expect that the abovementioned factors are complimentary and reinforce the ability of the firm to recover after crisis shock. We found strong support for the hypothesis that firms financing introduction of new products before the crisis and simultaneously managed to promote and sell them on the global market were rewarded by quick return to the growing path after global crisis. Other strategies, i.e. solely innovations without exporting play insignificant role while exporting without attempts to introduce new products contribute even negatively to post-crisis recover. Institutional environment also matters: in the regions with less level of corruption firms were more likely to grow after the crisis.

  19. Dynamic optimal strategies in transboundary pollution game under learning by doing

    Chang, Shuhua; Qin, Weihua; Wang, Xinyu

    2018-01-01

    In this paper, we present a transboundary pollution game, in which emission permits trading and pollution abatement costs under learning by doing are considered. In this model, the abatement cost mainly depends on the level of pollution abatement and the experience of using pollution abatement technology. We use optimal control theory to investigate the optimal emission paths and the optimal pollution abatement strategies under cooperative and noncooperative games, respectively. Additionally, the effects of parameters on the results have been examined.

  20. The Optimal Strategy to Research Pension Funds in China Based on the Loss Function

    Jian-wei Gao

    2007-10-01

    Full Text Available Based on the theory of actuarial present value, a pension fund investment goal can be formulated as an objective function. The mean-variance model is extended by defining the objective loss function. Furthermore, using the theory of stochastic optimal control, an optimal investment model is established under the minimum expectation of loss function. In the light of the Hamilton-Jacobi-Bellman (HJB equation, the analytic solution of the optimal investment strategy problem is derived.

  1. The Optimal Strategy to Research Pension Funds in China Based on the Loss Function

    Gao, Jian-wei; Guo, Hong-zhen; Ye, Yan-cheng

    2007-01-01

    Based on the theory of actuarial present value, a pension fund investment goal can be formulated as an objective function. The mean-variance model is extended by defining the objective loss function. Furthermore, using the theory of stochastic optimal control, an optimal investment model is established under the minimum expectation of loss function. In the light of the Hamilton-Jacobi-Bellman (HJB) equation, the analytic solution of the optimal investment strategy problem is derived.

  2. Optimal vaccination strategies against vector-borne diseases

    Græsbøll, Kaare; Enøe, Claes; Bødker, Rene

    2014-01-01

    Using a process oriented semi-agent based model, we simulated the spread of Bluetongue virus by Culicoides, biting midges, between cattle in Denmark. We evaluated the minimum vaccination cover and minimum cost for eight different preventive vaccination strategies in Denmark. The simulation model ...... results when index cases were in the vaccinated areas. However, given that the long-range spread of midge borne disease is still poorly quantified, more robust national vaccination schemes seem preferable....

  3. Optimal Pricing Strategy for Wireless Social Community Networks

    Mazloumian, Amin; Manshaei, Mohammad Hossein; Felegyhazi, Mark; Hubaux, Jean-Pierre

    2008-01-01

    The increasing number of mobile applications fuels the demand for affordable and ubiquitous wireless access. The traditional wireless network technologies such as EV-DO or WiMAX provide this service but require a huge upfront investment in infrastructure and spectrum. On the contrary, as they do not have to face such an investment, social community operators rely on subscribers who constitute a community of users. The pricing strategy of the provided wireless access is an open problem for thi...

  4. Optimization Strategy to Capitalize on the Romanian Tourism Potential

    PhD Lecturer Dindire Laura; PhD Reader Dugan Silvia

    2010-01-01

    An important direction of the improvement of promotional activities achieved both by the decisional governmental and non-governmental organisms within the tourist services sector and by the tourism firms, both on an intern and international level, is the promotional strategy. Consisting in the mastership of obtaining the best results, through organizing, coordination, prediction, communication and control activities, the promotional management means knowing and understanding the intern and in...

  5. Implementing the global plan to stop TB, 2011-2015--optimizing allocations and the Global Fund's contribution: a scenario projections study.

    Eline L Korenromp

    Full Text Available BACKGROUND: The Global Plan to Stop TB estimates funding required in low- and middle-income countries to achieve TB control targets set by the Stop TB Partnership within the context of the Millennium Development Goals. We estimate the contribution and impact of Global Fund investments under various scenarios of allocations across interventions and regions. METHODOLOGY/PRINCIPAL FINDINGS: Using Global Plan assumptions on expected cases and mortality, we estimate treatment costs and mortality impact for diagnosis and treatment for drug-sensitive and multidrug-resistant TB (MDR-TB, including antiretroviral treatment (ART during DOTS for HIV-co-infected patients, for four country groups, overall and for the Global Fund investments. In 2015, China and India account for 24% of funding need, Eastern Europe and Central Asia (EECA for 33%, sub-Saharan Africa (SSA for 20%, and other low- and middle-income countries for 24%. Scale-up of MDR-TB treatment, especially in EECA, drives an increasing global TB funding need--an essential investment to contain the mortality burden associated with MDR-TB and future disease costs. Funding needs rise fastest in SSA, reflecting increasing coverage need of improved TB/HIV management, which saves most lives per dollar spent in the short term. The Global Fund is expected to finance 8-12% of Global Plan implementation costs annually. Lives saved through Global Fund TB support within the available funding envelope could increase 37% if allocations shifted from current regional demand patterns to a prioritized scale-up of improved TB/HIV treatment and secondly DOTS, both mainly in Africa--with EECA region, which has disproportionately high per-patient costs, funded from alternative resources. CONCLUSIONS/SIGNIFICANCE: These findings, alongside country funding gaps, domestic funding and implementation capacity and equity considerations, should inform strategies and policies for international donors, national governments and

  6. Fueling strategies to optimize performance: training high or training low?

    Burke, L M

    2010-10-01

    Availability of carbohydrate as a substrate for the muscle and central nervous system is critical for the performance of both intermittent high-intensity work and prolonged aerobic exercise. Therefore, strategies that promote carbohydrate availability, such as ingesting carbohydrate before, during and after exercise, are critical for the performance of many sports and a key component of current sports nutrition guidelines. Guidelines for daily carbohydrate intakes have evolved from the "one size fits all" recommendation for a high-carbohydrate diets to an individualized approach to fuel needs based on the athlete's body size and exercise program. More recently, it has been suggested that athletes should train with low carbohydrate stores but restore fuel availability for competition ("train low, compete high"), based on observations that the intracellular signaling pathways underpinning adaptations to training are enhanced when exercise is undertaken with low glycogen stores. The present literature is limited to studies of "twice a day" training (low glycogen for the second session) or withholding carbohydrate intake during training sessions. Despite increasing the muscle adaptive response and reducing the reliance on carbohydrate utilization during exercise, there is no clear evidence that these strategies enhance exercise performance. Further studies on dietary periodization strategies, especially those mimicking real-life athletic practices, are needed. © 2010 John Wiley & Sons A/S.

  7. Pricing hospital care: Global budgets and marginal pricing strategies.

    Sutherland, Jason M

    2015-08-01

    The Canadian province of British Columbia (BC) is adding financial incentives to increase the volume of surgeries provided by hospitals using a marginal pricing approach. The objective of this study is to calculate marginal costs of surgeries based on assumptions regarding hospitals' availability of labor and equipment. This study is based on observational clinical, administrative and financial data generated by hospitals. Hospital inpatient and outpatient discharge summaries from the province are linked with detailed activity-based costing information, stratified by assigned case mix categorizations. To reflect a range of operating constraints governing hospitals' ability to increase their volume of surgeries, a number of scenarios are proposed. Under these scenarios, estimated marginal costs are calculated and compared to prices being offered as incentives to hospitals. Existing data can be used to support alternative strategies for pricing hospital care. Prices for inpatient surgeries do not generate positive margins under a range of operating scenarios. Hip and knee surgeries generate surpluses for hospitals even under the most costly labor conditions and are expected to generate additional volume. In health systems that wish to fine-tune financial incentives, setting prices that create incentives for additional volume should reflect knowledge of hospitals' underlying cost structures. Possible implications of mis-pricing include no response to the incentives or uneven increases in supply. Copyright © 2015 The Authors. Published by Elsevier Ireland Ltd.. All rights reserved.

  8. Material discovery by combining stochastic surface walking global optimization with a neural network.

    Huang, Si-Da; Shang, Cheng; Zhang, Xiao-Jie; Liu, Zhi-Pan

    2017-09-01

    While the underlying potential energy surface (PES) determines the structure and other properties of a material, it has been frustrating to predict new materials from theory even with the advent of supercomputing facilities. The accuracy of the PES and the efficiency of PES sampling are two major bottlenecks, not least because of the great complexity of the material PES. This work introduces a "Global-to-Global" approach for material discovery by combining for the first time a global optimization method with neural network (NN) techniques. The novel global optimization method, named the stochastic surface walking (SSW) method, is carried out massively in parallel for generating a global training data set, the fitting of which by the atom-centered NN produces a multi-dimensional global PES; the subsequent SSW exploration of large systems with the analytical NN PES can provide key information on the thermodynamics and kinetics stability of unknown phases identified from global PESs. We describe in detail the current implementation of the SSW-NN method with particular focuses on the size of the global data set and the simultaneous energy/force/stress NN training procedure. An important functional material, TiO 2 , is utilized as an example to demonstrate the automated global data set generation, the improved NN training procedure and the application in material discovery. Two new TiO 2 porous crystal structures are identified, which have similar thermodynamics stability to the common TiO 2 rutile phase and the kinetics stability for one of them is further proved from SSW pathway sampling. As a general tool for material simulation, the SSW-NN method provides an efficient and predictive platform for large-scale computational material screening.

  9. Improved quantum-behaved particle swarm optimization with local search strategy

    Maolong Xi

    2017-03-01

    Full Text Available Quantum-behaved particle swarm optimization, which was motivated by analysis of particle swarm optimization and quantum system, has shown compared performance in finding the optimal solutions for many optimization problems to other evolutionary algorithms. To address the problem of premature, a local search strategy is proposed to improve the performance of quantum-behaved particle swarm optimization. In proposed local search strategy, a super particle is presented which is a collection body of randomly selected particles’ dimension information in the swarm. The selected probability of particles in swarm is different and determined by their fitness values. To minimization problems, the fitness value of one particle is smaller; the selected probability is more and will contribute more information in constructing the super particle. In addition, in order to investigate the influence on algorithm performance with different local search space, four methods of computing the local search radius are applied in local search strategy and propose four variants of local search quantum-behaved particle swarm optimization. Empirical studies on a suite of well-known benchmark functions are undertaken in order to make an overall performance comparison among the proposed methods and other quantum-behaved particle swarm optimization. The simulation results show that the proposed quantum-behaved particle swarm optimization variants have better advantages over the original quantum-behaved particle swarm optimization.

  10. Hybrid surrogate-model-based multi-fidelity efficient global optimization applied to helicopter blade design

    Ariyarit, Atthaphon; Sugiura, Masahiko; Tanabe, Yasutada; Kanazaki, Masahiro

    2018-06-01

    A multi-fidelity optimization technique by an efficient global optimization process using a hybrid surrogate model is investigated for solving real-world design problems. The model constructs the local deviation using the kriging method and the global model using a radial basis function. The expected improvement is computed to decide additional samples that can improve the model. The approach was first investigated by solving mathematical test problems. The results were compared with optimization results from an ordinary kriging method and a co-kriging method, and the proposed method produced the best solution. The proposed method was also applied to aerodynamic design optimization of helicopter blades to obtain the maximum blade efficiency. The optimal shape obtained by the proposed method achieved performance almost equivalent to that obtained using the high-fidelity, evaluation-based single-fidelity optimization. Comparing all three methods, the proposed method required the lowest total number of high-fidelity evaluation runs to obtain a converged solution.

  11. Integrated Emission Management strategy for cost-optimal engine-aftertreatment operation

    Cloudt, R.P.M.; Willems, F.P.T.

    2011-01-01

    A new cost-based control strategy is presented that optimizes engine-aftertreatment performance under all operating conditions. This Integrated Emission Management strategy minimizes fuel consumption within the set emission limits by on-line adjustment of air management based on the actual state of

  12. Optimization as a Reasoning Strategy for Dealing with Socioscientific Decision-Making Situations

    Papadouris, Nicos

    2012-01-01

    This paper reports on an attempt to help 12-year-old students develop a specific optimization strategy for selecting among possible solutions in socioscientific decision-making situations. We have developed teaching and learning materials for elaborating this strategy, and we have implemented them in two intact classes (N = 48). Prior to and after…

  13. Exploring optimal fertigation strategies for orange production, using soil-crop modelling

    Qin, Wei; Heinen, Marius; Assinck, Falentijn B.T.; Oenema, Oene

    2016-01-01

    Water and nitrogen (N) are two key limiting factors in orange (Citrus sinensis) production. The amount and the timing of water and N application are critical, but optimal strategies have not yet been well established. This study presents an analysis of 47 fertigation strategies examined by a

  14. Optimal Coordinated Strategy Analysis for the Procurement Logistics of a Steel Group

    Lianbo Deng

    2014-01-01

    Full Text Available This paper focuses on the optimization of an internal coordinated procurement logistics system in a steel group and the decision on the coordinated procurement strategy by minimizing the logistics costs. Considering the coordinated procurement strategy and the procurement logistics costs, the aim of the optimization model was to maximize the degree of quality satisfaction and to minimize the procurement logistics costs. The model was transformed into a single-objective model and solved using a simulated annealing algorithm. In the algorithm, the supplier of each subsidiary was selected according to the evaluation result for independent procurement. Finally, the effect of different parameters on the coordinated procurement strategy was analysed. The results showed that the coordinated strategy can clearly save procurement costs; that the strategy appears to be more cooperative when the quality requirement is not stricter; and that the coordinated costs have a strong effect on the coordinated procurement strategy.

  15. Optimization Strategy of the APR+ BOP Technical Specifications

    Cho, Yoon Sang; Lee, Jae Gon; Han, Sung Heum

    2016-01-01

    The BOP is one of the key factors for successful project implementation of NPP. In constructing the APR1400 NPP, the BOP procurement has been one of the biggest concerns. Due to the design changes and increased capacity of equipment in NPP, lots of BOPs should be ‘first supplied equipment’ [hereinafter, ‘FSE’]. The manufacture-ability, and the performances of FSEs have not been fully proved and tested, manufacturers and suppliers are requested to submit Reports for Equipment Qualification Evaluation in accordance with 10 CFR 50.49, IEEE 323. They need at least 1-2 years’ tests for Environment Qualification (EQ) and Seismic Qualification (SQ). This study is focused how to prepare the BOP purchase specifications in order to control the FSEs, especially in safety class equipment. With the optimization plan for BOP packages of this study, the FSEs’ occurrence can be reasonably controlled as low as possible. For successful NPP project, the concerns in procuring BOPs shall be fully analyzed beforehand. Now Korea is preparing new era of APR+, with closing the time of APR1400. The technical specification of APR+ BOPs can be developed and prepared successfully and very effectively according to this optimization plan. This will be a great contribution not only in constructing APR+ in time, but also in exporting APR+ overseas, all over the world in the future

  16. Optimization Strategy of the APR+ BOP Technical Specifications

    Cho, Yoon Sang; Lee, Jae Gon; Han, Sung Heum [KHNP CRI, Daejeon (Korea, Republic of)

    2016-10-15

    The BOP is one of the key factors for successful project implementation of NPP. In constructing the APR1400 NPP, the BOP procurement has been one of the biggest concerns. Due to the design changes and increased capacity of equipment in NPP, lots of BOPs should be ‘first supplied equipment’ [hereinafter, ‘FSE’]. The manufacture-ability, and the performances of FSEs have not been fully proved and tested, manufacturers and suppliers are requested to submit Reports for Equipment Qualification Evaluation in accordance with 10 CFR 50.49, IEEE 323. They need at least 1-2 years’ tests for Environment Qualification (EQ) and Seismic Qualification (SQ). This study is focused how to prepare the BOP purchase specifications in order to control the FSEs, especially in safety class equipment. With the optimization plan for BOP packages of this study, the FSEs’ occurrence can be reasonably controlled as low as possible. For successful NPP project, the concerns in procuring BOPs shall be fully analyzed beforehand. Now Korea is preparing new era of APR+, with closing the time of APR1400. The technical specification of APR+ BOPs can be developed and prepared successfully and very effectively according to this optimization plan. This will be a great contribution not only in constructing APR+ in time, but also in exporting APR+ overseas, all over the world in the future.

  17. Calibration of an agricultural-hydrological model (RZWQM2) using surrogate global optimization

    Xi, Maolong; Lu, Dan; Gui, Dongwei; Qi, Zhiming; Zhang, Guannan

    2017-01-01

    Robust calibration of an agricultural-hydrological model is critical for simulating crop yield and water quality and making reasonable agricultural management. However, calibration of the agricultural-hydrological system models is challenging because of model complexity, the existence of strong parameter correlation, and significant computational requirements. Therefore, only a limited number of simulations can be allowed in any attempt to find a near-optimal solution within an affordable time, which greatly restricts the successful application of the model. The goal of this study is to locate the optimal solution of the Root Zone Water Quality Model (RZWQM2) given a limited simulation time, so as to improve the model simulation and help make rational and effective agricultural-hydrological decisions. To this end, we propose a computationally efficient global optimization procedure using sparse-grid based surrogates. We first used advanced sparse grid (SG) interpolation to construct a surrogate system of the actual RZWQM2, and then we calibrate the surrogate model using the global optimization algorithm, Quantum-behaved Particle Swarm Optimization (QPSO). As the surrogate model is a polynomial with fast evaluation, it can be efficiently evaluated with a sufficiently large number of times during the optimization, which facilitates the global search. We calibrate seven model parameters against five years of yield, drain flow, and NO3-N loss data from a subsurface-drained corn-soybean field in Iowa. Results indicate that an accurate surrogate model can be created for the RZWQM2 with a relatively small number of SG points (i.e., RZWQM2 runs). Compared to the conventional QPSO algorithm, our surrogate-based optimization method can achieve a smaller objective function value and better calibration performance using a fewer number of expensive RZWQM2 executions, which greatly improves computational efficiency.

  18. Optimal investment strategies and hedging of derivatives in the presence of transaction costs (Invited Paper)

    Muratore-Ginanneschi, Paolo

    2005-05-01

    Investment strategies in multiplicative Markovian market models with transaction costs are defined using growth optimal criteria. The optimal strategy is shown to consist in holding the amount of capital invested in stocks within an interval around an ideal optimal investment. The size of the holding interval is determined by the intensity of the transaction costs and the time horizon. The inclusion of financial derivatives in the models is also considered. All the results presented in this contributions were previously derived in collaboration with E. Aurell.

  19. Optimization of maintenance strategies in case of data uncertainties; Optimierung von Instandhaltungsstrategien bei unscharfen Eingangsdaten

    Aha, Ulrich

    2013-07-01

    Maintenance strategies are aimed to keep a technical facility functioning in spite of damaging processes (wear, corrosion, fatigue) with simultaneous control of these processes. The project optimization of maintenance strategies in case of data uncertainties is aimed to optimize maintenance measures like preventive measures (lubrication etc.), inspections and replacements to keep the facility/plant operating including the minimization of financial costs. The report covers the following topics: modeling assumptions, model development and optimization procedure, results for a conventional power plant and an oxyfuel plant.

  20. Multi-step optimization strategy for fuel-optimal orbital transfer of low-thrust spacecraft

    Rasotto, M.; Armellin, R.; Di Lizia, P.

    2016-03-01

    An effective method for the design of fuel-optimal transfers in two- and three-body dynamics is presented. The optimal control problem is formulated using calculus of variation and primer vector theory. This leads to a multi-point boundary value problem (MPBVP), characterized by complex inner constraints and a discontinuous thrust profile. The first issue is addressed by embedding the MPBVP in a parametric optimization problem, thus allowing a simplification of the set of transversality constraints. The second problem is solved by representing the discontinuous control function by a smooth function depending on a continuation parameter. The resulting trajectory optimization method can deal with different intermediate conditions, and no a priori knowledge of the control structure is required. Test cases in both the two- and three-body dynamics show the capability of the method in solving complex trajectory design problems.