WorldWideScience

Sample records for global motion integration

  1. Robust Myocardial Motion Tracking for Echocardiography: Variational Framework Integrating Local-to-Global Deformation

    Chi Young Ahn

    2013-01-01

    Full Text Available This paper proposes a robust real-time myocardial border tracking algorithm for echocardiography. Commonly, after an initial contour of LV border is traced at one or two frames from the entire cardiac cycle, LV contour tracking is performed over the remaining frames. Among a variety of tracking techniques, optical flow method is the most widely used for motion estimation of moving objects. However, when echocardiography data is heavily corrupted in some local regions, the errors bring the tracking point out of the endocardial border, resulting in distorted LV contours. This shape distortion often occurs in practice since the data acquisition is affected by ultrasound artifacts, dropouts, or shadowing phenomena of cardiac walls. The proposed method is designed to deal with this shape distortion problem by integrating local optical flow motion and global deformation into a variational framework. The proposed descent method controls the individual tracking points to follow the local motions of a specific speckle pattern, while their overall motions are confined to the global motion constraint being approximately an affine transform of the initial tracking points. Many real experiments show that the proposed method achieves better overall performance than conventional methods.

  2. Unconscious Local Motion Alters Global Image Speed

    Khuu, Sieu K.; Chung, Charles Y. L.; Lord, Stephanie; Pearson, Joel

    2014-01-01

    Accurate motion perception of self and object speed is crucial for successful interaction in the world. The context in which we make such speed judgments has a profound effect on their accuracy. Misperceptions of motion speed caused by the context can have drastic consequences in real world situations, but they also reveal much about the underlying mechanisms of motion perception. Here we show that motion signals suppressed from awareness can warp simultaneous conscious speed perception. In Experiment 1, we measured global speed discrimination thresholds using an annulus of 8 local Gabor elements. We show that physically removing local elements from the array attenuated global speed discrimination. However, removing awareness of the local elements only had a small effect on speed discrimination. That is, unconscious local motion elements contributed to global conscious speed perception. In Experiment 2 we measured the global speed of the moving Gabor patterns, when half the elements moved at different speeds. We show that global speed averaging occurred regardless of whether local elements were removed from awareness, such that the speed of invisible elements continued to be averaged together with the visible elements to determine the global speed. These data suggest that contextual motion signals outside of awareness can both boost and affect our experience of motion speed, and suggest that such pooling of motion signals occurs before the conscious extraction of the surround motion speed. PMID:25503603

  3. Why do adults with dyslexia have poor global motion sensitivity?

    Elizabeth eConlon

    2013-12-01

    Full Text Available Two experiments aimed to determine why adults with dyslexia have higher global motion thresholds than typically reading controls. In Experiment 1, the dot density and number of animation frames presented in the dot stimulus were manipulated because of findings that use of a high dot density can normalise coherence thresholds in individuals with dyslexia. Dot densities were 14.15 dots/deg2 and 3.54 dots/deg2. These were presented for five (84ms or eight (134ms frames. The dyslexia group had higher coherence thresholds in all conditions than controls. However, in the high dot density, long duration condition, both reader groups had the lowest thresholds indicating normal temporal recruitment. These results indicated that the dyslexia group could sample the additional signals dots over space and then integrate these with the same efficiency as controls. In Experiment 2, we determined whether briefly presenting a fully coherent prime moving in either the same or opposite direction of motion to a partially coherent test stimulus would systematically increase and decrease global motion thresholds in the reader groups. When the direction of motion in the prime and test was the same, global motion thresholds increased for both reader groups. The increase in coherence thresholds was significantly greater for the dyslexia group. When the motion of the prime and test were presented in opposite directions, coherence thresholds were reduced in both groups. No group threshold differences were found. We concluded that the global motion processing deficit found in adults with dyslexia can be explained by undersampling of the target motion signals. This might occur because of difficulties directing attention to the relevant motion signals in the random dot pattern, and not a specific difficulty integrating global motion signals. These effects are most likely to occur in the group with dyslexia when more complex computational processes are required to process

  4. Why do adults with dyslexia have poor global motion sensitivity?

    Conlon, Elizabeth G; Lilleskaret, Gry; Wright, Craig M; Stuksrud, Anne

    2013-01-01

    Two experiments aimed to determine why adults with dyslexia have higher global motion thresholds than typically reading controls. In Experiment 1, the dot density and number of animation frames presented in the dot stimulus were manipulated because of findings that use of a high dot density can normalize coherence thresholds in individuals with dyslexia. Dot densities were 14.15 and 3.54 dots/deg(2). These were presented for five (84 ms) or eight (134 ms) frames. The dyslexia group had higher coherence thresholds in all conditions than controls. However, in the high dot density, long duration condition, both reader groups had the lowest thresholds indicating normal temporal recruitment. These results indicated that the dyslexia group could sample the additional signals dots over space and then integrate these with the same efficiency as controls. In Experiment 2, we determined whether briefly presenting a fully coherent prime moving in either the same or opposite direction of motion to a partially coherent test stimulus would systematically increase and decrease global motion thresholds in the reader groups. When the direction of motion in the prime and test was the same, global motion thresholds increased for both reader groups. The increase in coherence thresholds was significantly greater for the dyslexia group. When the motion of the prime and test were presented in opposite directions, coherence thresholds were reduced in both groups. No group threshold differences were found. We concluded that the global motion processing deficit found in adults with dyslexia can be explained by undersampling of the target motion signals. This might occur because of difficulties directing attention to the relevant motion signals in the random dot pattern, and not a specific difficulty integrating global motion signals. These effects are most likely to occur in the group with dyslexia when more complex computational processes are required to process global motion.

  5. European Integration and Globalization

    Diana Bobica

    2010-06-01

    Full Text Available According to many, the term globalization is able to explain any phenomenon whatsoever, be it positive or negative, that takes place within the global social system. It seems like a sort of magical formula, which is to be found in the speeches of all sorts of people, be they economists, politicians, businessmen or sociologists. However this magical formula of globalization has its limitations, since it encompasses a certain amount of quibbling, beyond which not many can pass. In the context of globalization there appears the question on its role in the process of European integration. Is European integration a part of this global process or, quite on the contrary, does it present certain distinctive features, as it moulds itself differently from the globalization phenomenon? A clear-cut answer seems difficult because of the various aspects involved. Not only the general phenomenon of globalization, but also the economic integration on European level is based on the liberalization of markets and on the opening of national economies towards the exterior,having as direct consequence the intensification of trade exchanges. If from a global point of view one may talk of a market fundamentalism in that the market principles know no boundary, European integration on the other hand implies not only market economy, but also a guided and monitored action of Member Statesaccording to the needs of the whole entity, also taking into consideration - as far as possible – all aspects and consequences on social level.

  6. Global Operations Networks in Motion

    Slepniov, Dmitrij; Jørgensen, Claus; Wæhrens, Brian Vejrum

    2009-01-01

    This paper addresses the phenomenon of global operations networks and how they change over time. The paper is based on the cases of three Danish companies and their global operations networks. It finds a number of common patterns highlighting some organisational effects and managerial challenges...... the companies face regarding rapid changes in their networks configurations and capabilities. The paper details the variables determining these changes and suggests how the on-going interplay between the focal organisation, its network partners, and their various contextual conditions can be approached....

  7. GLobal Integrated Design Environment

    Kunkel, Matthew; McGuire, Melissa; Smith, David A.; Gefert, Leon P.

    2011-01-01

    The GLobal Integrated Design Environment (GLIDE) is a collaborative engineering application built to resolve the design session issues of real-time passing of data between multiple discipline experts in a collaborative environment. Utilizing Web protocols and multiple programming languages, GLIDE allows engineers to use the applications to which they are accustomed in this case, Excel to send and receive datasets via the Internet to a database-driven Web server. Traditionally, a collaborative design session consists of one or more engineers representing each discipline meeting together in a single location. The discipline leads exchange parameters and iterate through their respective processes to converge on an acceptable dataset. In cases in which the engineers are unable to meet, their parameters are passed via e-mail, telephone, facsimile, or even postal mail. The result of this slow process of data exchange would elongate a design session to weeks or even months. While the iterative process remains in place, software can now exchange parameters securely and efficiently, while at the same time allowing for much more information about a design session to be made available. GLIDE is written in a compilation of several programming languages, including REALbasic, PHP, and Microsoft Visual Basic. GLIDE client installers are available to download for both Microsoft Windows and Macintosh systems. The GLIDE client software is compatible with Microsoft Excel 2000 or later on Windows systems, and with Microsoft Excel X or later on Macintosh systems. GLIDE follows the Client-Server paradigm, transferring encrypted and compressed data via standard Web protocols. Currently, the engineers use Excel as a front end to the GLIDE Client, as many of their custom tools run in Excel.

  8. Teaching Motion with the Global Positioning System

    Budisa, Marko; Planinsic, Gorazd

    2003-01-01

    We have used the GPS receiver and a PC interface to track different types of motion. Various hands-on experiments that enlighten the physics of motion at the secondary school level are suggested (visualization of 2D and 3D motion, measuring car drag coefficient and fuel consumption). (Contains 8 figures.)

  9. Integrated Surface Dataset (Global)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Surface (ISD) Dataset (ISD) is composed of worldwide surface weather observations from over 35,000 stations, though the best spatial coverage is...

  10. Estimation of the global regularity of a multifractional Brownian motion

    Lebovits, Joachim; Podolskij, Mark

    This paper presents a new estimator of the global regularity index of a multifractional Brownian motion. Our estimation method is based upon a ratio statistic, which compares the realized global quadratic variation of a multifractional Brownian motion at two different frequencies. We show that a ...... that a logarithmic transformation of this statistic converges in probability to the minimum of the Hurst functional parameter, which is, under weak assumptions, identical to the global regularity index of the path....

  11. Multiscale sampling model for motion integration.

    Sherbakov, Lena; Yazdanbakhsh, Arash

    2013-09-30

    Biologically plausible strategies for visual scene integration across spatial and temporal domains continues to be a challenging topic. The fundamental question we address is whether classical problems in motion integration, such as the aperture problem, can be solved in a model that samples the visual scene at multiple spatial and temporal scales in parallel. We hypothesize that fast interareal connections that allow feedback of information between cortical layers are the key processes that disambiguate motion direction. We developed a neural model showing how the aperture problem can be solved using different spatial sampling scales between LGN, V1 layer 4, V1 layer 6, and area MT. Our results suggest that multiscale sampling, rather than feedback explicitly, is the key process that gives rise to end-stopped cells in V1 and enables area MT to solve the aperture problem without the need for calculating intersecting constraints or crafting intricate patterns of spatiotemporal receptive fields. Furthermore, the model explains why end-stopped cells no longer emerge in the absence of V1 layer 6 activity (Bolz & Gilbert, 1986), why V1 layer 4 cells are significantly more end-stopped than V1 layer 6 cells (Pack, Livingstone, Duffy, & Born, 2003), and how it is possible to have a solution to the aperture problem in area MT with no solution in V1 in the presence of driving feedback. In summary, while much research in the field focuses on how a laminar architecture can give rise to complicated spatiotemporal receptive fields to solve problems in the motion domain, we show that one can reframe motion integration as an emergent property of multiscale sampling achieved concurrently within lamina and across multiple visual areas.

  12. Adiabatic invariance with first integrals of motion

    Adib, Artur B.

    2002-10-01

    The construction of a microthermodynamic formalism for isolated systems based on the concept of adiabatic invariance is an old but seldom appreciated effort in the literature, dating back at least to P. Hertz [Ann. Phys. (Leipzig) 33, 225 (1910)]. An apparently independent extension of such formalism for systems bearing additional first integrals of motion was recently proposed by Hans H. Rugh [Phys. Rev. E 64, 055101 (2001)], establishing the concept of adiabatic invariance even in such singular cases. After some remarks in connection with the formalism pioneered by Hertz, it will be suggested that such an extension can incidentally explain the success of a dynamical method for computing the entropy of classical interacting fluids, at least in some potential applications where the presence of additional first integrals cannot be ignored.

  13. Towards Integrated Marmara Strong Motion Network

    Durukal, E.; Erdik, M.; Safak, E.; Ansal, A.; Ozel, O.; Alcik, H.; Mert, A.; Kafadar, N.; Korkmaz, A.; Kurtulus, A.

    2009-04-01

    Istanbul has a 65% chance of having a magnitude 7 or above earthquake within the next 30 years. As part of the preparations for the future earthquake, strong motion networks have been installed in and around Istanbul. The Marmara Strong Motion Network, operated by the Department of Earthquake Engineering of Kandilli Observatory and Earthquake Research Institute, encompasses permanent systems outlined below. It is envisaged that the networks will be run by a single entity responsible for technical management and maintanence, as well as for data management, archiving and dissemination through dedicated web-based interfaces. • Istanbul Earthquake Rapid Response and Early Warning System - IERREWS (one hundred 18-bit accelerometers for rapid response; ten 24-bit accelerometers for early warning) • IGDAŞ Gas Shutoff Network (100 accelerometers to be installed in 2010 and integrated with IERREWS) • Structural Monitoring Arrays - Fatih Sultan Mehmet Suspension Bridge (1200m-long suspension bridge across the Bosphorus, five 3-component accelerometers + GPS sensors) - Hagia Sophia Array (1500-year-old historical edifice, 9 accelerometers) - Süleymaniye Mosque Array (450-year-old historical edifice,9 accelerometers) - Fatih Mosque Array (237-year-old historical edifice, 9 accelerometers) - Kanyon Building Array (high-rise office building, 5 accelerometers) - Isbank Tower Array (high-rise office building, 5 accelerometers) - ENRON Array (power generation facility, 4 acelerometers) - Mihrimah Sultan Mosque Array (450-year-old historical edifice,9 accelerometers + tiltmeters, to be installed in 2009) - Sultanahmet Mosque Array, (390-year-old historical edifice, 9 accelerometers + tiltmeters, to be installed in 2009) • Special Arrays - Atakoy Vertical Array (four 3-component accelerometers at 25, 50, 75, and 150 m depths) - Marmara Tube Tunnel (1400 m long submerged tunnel, 128 ch. accelerometric data, 24 ch. strain data, to be installed in 2010) - Air-Force Academy

  14. Visual-vestibular integration motion perception reporting

    Harm, Deborah L.; Reschke, Millard R.; Parker, Donald E.

    1999-01-01

    Self-orientation and self/surround-motion perception derive from a multimodal sensory process that integrates information from the eyes, vestibular apparatus, proprioceptive and somatosensory receptors. Results from short and long duration spaceflight investigations indicate that: (1) perceptual and sensorimotor function was disrupted during the initial exposure to microgravity and gradually improved over hours to days (individuals adapt), (2) the presence and/or absence of information from different sensory modalities differentially affected the perception of orientation, self-motion and surround-motion, (3) perceptual and sensorimotor function was initially disrupted upon return to Earth-normal gravity and gradually recovered to preflight levels (individuals readapt), and (4) the longer the exposure to microgravity, the more complete the adaptation, the more profound the postflight disturbances, and the longer the recovery period to preflight levels. While much has been learned about perceptual and sensorimotor reactions and adaptation to microgravity, there is much remaining to be learned about the mechanisms underlying the adaptive changes, and about how intersensory interactions affect perceptual and sensorimotor function during voluntary movements. During space flight, SMS and perceptual disturbances have led to reductions in performance efficiency and sense of well-being. During entry and immediately after landing, such disturbances could have a serious impact on the ability of the commander to land the Orbiter and on the ability of all crew members to egress from the Orbiter, particularly in a non-nominal condition or following extended stays in microgravity. An understanding of spatial orientation and motion perception is essential for developing countermeasures for Space Motion Sickness (SMS) and perceptual disturbances during spaceflight and upon return to Earth. Countermeasures for optimal performance in flight and a successful return to Earth require

  15. MANAGING GLOBAL OPERATIONS NETWORKS IN MOTION

    Slepniov, Dmitrij; Jørgensen, Claus; Sørensen, Brian Vejrum

    2008-01-01

    capabilities and intensified need for transfer, assimilation and augmentation of activities and know-how within the network. Based on these the paper highlights some organisational effects and managerial challenges the companies face regarding rapid changes in their networks configurations and capabilities.......Most industrial companies are, for reasons related to cost, market access or knowledge, working with some aspect of offshore operations. This may take form of captive operations or through outsourcing of activities overseas. With this trend, global operations networks are emerging resulting...... in corporate strategic repositioning, re-configurations of sites, and changes to the underlying capabilities. The paper is based on cases of 3 Danish companies and their global supply networks. These networks are not in a steady state, they evolve as a consequence of the ongoing co-evolution between the focal...

  16. Approximate motion integrals and the quantum chaos problem

    Bunakov, V.E.; Ivanov, I.B.

    2001-01-01

    One discusses the problem of occurrence and seek for the motion integrals in the stationary quantum mechanics and its relation to the quantum chaos. One studies decomposition of quantum numbers and derives the criterion of chaos. To seek the motion integrals one applies the convergence method. One derived the approximate integrals in the Hennone-Hales problem. One discusses the problem of compatibility of chaos and integrability [ru

  17. An Integrated Approach to Motion and Sound

    Hahn, James K; Geigel, Joe; Lee, Jong W; Gritz, Larry; Takala, Tapio; Mishra, Suneil

    1995-01-01

    Until recently, sound has been given little attention in computer graphics and related domains of computer animation and virtual environments, although sounds which are properly synchronized to motion...

  18. Integrals of motion in the many-body localized phase

    V. Ros

    2015-02-01

    Full Text Available We construct a complete set of quasi-local integrals of motion for the many-body localized phase of interacting fermions in a disordered potential. The integrals of motion can be chosen to have binary spectrum {0,1}, thus constituting exact quasiparticle occupation number operators for the Fermi insulator. We map the problem onto a non-Hermitian hopping problem on a lattice in operator space. We show how the integrals of motion can be built, under certain approximations, as a convergent series in the interaction strength. An estimate of its radius of convergence is given, which also provides an estimate for the many-body localization–delocalization transition. Finally, we discuss how the properties of the operator expansion for the integrals of motion imply the presence or absence of a finite temperature transition.

  19. INS integrated motion analysis for autonomous vehicle navigation

    Roberts, Barry; Bazakos, Mike

    1991-01-01

    The use of inertial navigation system (INS) measurements to enhance the quality and robustness of motion analysis techniques used for obstacle detection is discussed with particular reference to autonomous vehicle navigation. The approach to obstacle detection used here employs motion analysis of imagery generated by a passive sensor. Motion analysis of imagery obtained during vehicle travel is used to generate range measurements to points within the field of view of the sensor, which can then be used to provide obstacle detection. Results obtained with an INS integrated motion analysis approach are reviewed.

  20. Infinite number of integrals of motion in classically integrable system with boundary: Pt.2

    Chen Yixin; Luo Xudong

    1998-01-01

    In Affine Toda field theory, links among three generating functions for integrals of motion derived from Part (I) are studied, and some classically integrable boundary conditions are obtained. An infinite number of integrals of motion are calculated in ZMS model with quasi-periodic condition. The authors find the classically integrable boundary conditions and K +- matrices of ZMS model with independent boundary conditions on each end. It is identified that an infinite number of integrals of motion does exist and one of them is the Hamiltonian, so this system is completely integrable

  1. Circuit Mechanisms Governing Local vs. Global Motion Processing in Mouse Visual Cortex

    Rune Rasmussen

    2017-12-01

    Full Text Available A withstanding question in neuroscience is how neural circuits encode representations and perceptions of the external world. A particularly well-defined visual computation is the representation of global object motion by pattern direction-selective (PDS cells from convergence of motion of local components represented by component direction-selective (CDS cells. However, how PDS and CDS cells develop their distinct response properties is still unresolved. The visual cortex of the mouse is an attractive model for experimentally solving this issue due to the large molecular and genetic toolbox available. Although mouse visual cortex lacks the highly ordered orientation columns of primates, it is organized in functional sub-networks and contains striate- and extrastriate areas like its primate counterparts. In this Perspective article, we provide an overview of the experimental and theoretical literature on global motion processing based on works in primates and mice. Lastly, we propose what types of experiments could illuminate what circuit mechanisms are governing cortical global visual motion processing. We propose that PDS cells in mouse visual cortex appear as the perfect arena for delineating and solving how individual sensory features extracted by neural circuits in peripheral brain areas are integrated to build our rich cohesive sensory experiences.

  2. Global integration in times of crisis

    Jensen, Camilla

    shock) from other subsidiaries downstream in the value chain. While in a comparative perspective multinational subsidiaries are found to perform relatively better than local firms that are integrated differently (arms' length) in global production networks (e.g. offshoring outsourcing). This paper tries...... to reconcile these findings by testing a number of hypothesis about global integration strategies in the context of the global financial crisis and how it affected exporting among multinational subsidiaries operating out of Turkey. Controlling for the impact that depreciations and exchange rate volatility has...... integration strategies throughout the course of the global financial crisis....

  3. Near-optimal integration of facial form and motion.

    Dobs, Katharina; Ma, Wei Ji; Reddy, Leila

    2017-09-08

    Human perception consists of the continuous integration of sensory cues pertaining to the same object. While it has been fairly well shown that humans use an optimal strategy when integrating low-level cues proportional to their relative reliability, the integration processes underlying high-level perception are much less understood. Here we investigate cue integration in a complex high-level perceptual system, the human face processing system. We tested cue integration of facial form and motion in an identity categorization task and found that an optimal model could successfully predict subjects' identity choices. Our results suggest that optimal cue integration may be implemented across different levels of the visual processing hierarchy.

  4. Neural Circuit to Integrate Opposing Motions in the Visual Field.

    Mauss, Alex S; Pankova, Katarina; Arenz, Alexander; Nern, Aljoscha; Rubin, Gerald M; Borst, Alexander

    2015-07-16

    When navigating in their environment, animals use visual motion cues as feedback signals that are elicited by their own motion. Such signals are provided by wide-field neurons sampling motion directions at multiple image points as the animal maneuvers. Each one of these neurons responds selectively to a specific optic flow-field representing the spatial distribution of motion vectors on the retina. Here, we describe the discovery of a group of local, inhibitory interneurons in the fruit fly Drosophila key for filtering these cues. Using anatomy, molecular characterization, activity manipulation, and physiological recordings, we demonstrate that these interneurons convey direction-selective inhibition to wide-field neurons with opposite preferred direction and provide evidence for how their connectivity enables the computation required for integrating opposing motions. Our results indicate that, rather than sharpening directional selectivity per se, these circuit elements reduce noise by eliminating non-specific responses to complex visual information. Copyright © 2015 Elsevier Inc. All rights reserved.

  5. Proton spin tracking with symplectic integration of orbit motion

    Luo, Y. [Brookhaven National Lab. (BNL), Upton, NY (United States); Dutheil, Y. [Brookhaven National Lab. (BNL), Upton, NY (United States); Huang, H. [Brookhaven National Lab. (BNL), Upton, NY (United States); Meot, F. [Brookhaven National Lab. (BNL), Upton, NY (United States); Ranjbar, V. [Brookhaven National Lab. (BNL), Upton, NY (United States)

    2015-05-03

    Symplectic integration had been adopted for orbital motion tracking in code SimTrack. SimTrack has been extensively used for dynamic aperture calculation with beam-beam interaction for the Relativistic Heavy Ion Collider (RHIC). Recently proton spin tracking has been implemented on top of symplectic orbital motion in this code. In this article, we will explain the implementation of spin motion based on Thomas-BMT equation, and the benchmarking with other spin tracking codes currently used for RHIC. Examples to calculate spin closed orbit and spin tunes are presented too.

  6. Fuzzy Itand#244; Integral Driven by a Fuzzy Brownian Motion

    Didier Kumwimba Seya

    2015-11-01

    Full Text Available In this paper we take into account the fuzzy stochastic integral driven by fuzzy Brownian motion. To define the metric between two fuzzy numbers and to take into account the limit of a sequence of fuzzy numbers, we invoke the Hausdorff metric. First this fuzzy stochastic integral is constructed for fuzzy simple stochastic functions, then the construction is done for fuzzy stochastic integrable functions.

  7. Canonical algorithms for numerical integration of charged particle motion equations

    Efimov, I. N.; Morozov, E. A.; Morozova, A. R.

    2017-02-01

    A technique for numerically integrating the equation of charged particle motion in a magnetic field is considered. It is based on the canonical transformations of the phase space in Hamiltonian mechanics. The canonical transformations make the integration process stable against counting error accumulation. The integration algorithms contain a minimum possible amount of arithmetics and can be used to design accelerators and devices of electron and ion optics.

  8. Integrals of motion for one-dimensional Anderson localized systems

    Modak, Ranjan; Mukerjee, Subroto; Yuzbashyan, Emil A; Shastry, B Sriram

    2016-01-01

    Anderson localization is known to be inevitable in one-dimension for generic disordered models. Since localization leads to Poissonian energy level statistics, we ask if localized systems possess ‘additional’ integrals of motion as well, so as to enhance the analogy with quantum integrable systems. We answer this in the affirmative in the present work. We construct a set of nontrivial integrals of motion for Anderson localized models, in terms of the original creation and annihilation operators. These are found as a power series in the hopping parameter. The recently found Type-1 Hamiltonians, which are known to be quantum integrable in a precise sense, motivate our construction. We note that these models can be viewed as disordered electron models with infinite-range hopping, where a similar series truncates at the linear order. We show that despite the infinite range hopping, all states but one are localized. We also study the conservation laws for the disorder free Aubry–Andre model, where the states are either localized or extended, depending on the strength of a coupling constant. We formulate a specific procedure for averaging over disorder, in order to examine the convergence of the power series. Using this procedure in the Aubry–Andre model, we show that integrals of motion given by our construction are well-defined in localized phase, but not so in the extended phase. Finally, we also obtain the integrals of motion for a model with interactions to lowest order in the interaction. (paper)

  9. Inertial navigation sensor integrated motion analysis for autonomous vehicle navigation

    Roberts, Barry; Bhanu, Bir

    1992-01-01

    Recent work on INS integrated motion analysis is described. Results were obtained with a maximally passive system of obstacle detection (OD) for ground-based vehicles and rotorcraft. The OD approach involves motion analysis of imagery acquired by a passive sensor in the course of vehicle travel to generate range measurements to world points within the sensor FOV. INS data and scene analysis results are used to enhance interest point selection, the matching of the interest points, and the subsequent motion-based computations, tracking, and OD. The most important lesson learned from the research described here is that the incorporation of inertial data into the motion analysis program greatly improves the analysis and makes the process more robust.

  10. Integrated Global Radiosonde Archive (IGRA) Version 2

    National Oceanic and Atmospheric Administration, Department of Commerce — Integrated Global Radiosonde Archive (IGRA) Version 2 consists of quality-controlled radiosonde observations of temperature, humidity, and wind at stations across...

  11. Additional integrals of the motion of classical Hamiltonian wave systems

    Shul'man, E.I.

    1989-01-01

    It is shown that a classical Hamiltonian wave system that possesses at least one additional integral of the motion with quadratic principal part has an infinite number of such integrals in the cases of both nondegenerate and degenerate dispersion laws. Conditions under which in a space of dimension d ≥ 2 a system with nondegenerate dispersion law is completely integratable and its Hamiltonian can be reduced to normal form are found. In the case of a degenerate dispersion law integrals are not sufficient for complete integrability

  12. The global economic integration has no prospects without global currency

    Sajnoski, Krste; Paceskoski, Vlatko; Davcev, Ljupco

    2013-01-01

    After getting out of the recession as it is, into which the developed countries have fallen, the continuation of the processes of global economic integration becomes a priority task of the contemporary international economic relations. For its accomplishment, there has to be stopped the sharpening of global imbalances, it has to be ceased the taking of protectionist measures in relation to the competing economies, to be eliminated the danger of carrying out competing devaluations of national ...

  13. Integrated risk analysis of global climate change

    Shlyakhter, Alexander; Wilson, Richard; Valverde A, L.J. Jr.

    1995-01-01

    This paper discusses several factors that should be considered in integrated risk analyses of global climate change. We begin by describing how the problem of global climate change can be subdivided into largely independent parts that can be linked together in an analytically tractable fashion. Uncertainty plays a central role in integrated risk analyses of global climate change. Accordingly, we consider various aspects of uncertainty as they relate to the climate change problem. We also consider the impacts of these uncertainties on various risk management issues, such as sequential decision strategies, value of information, and problems of interregional and intergenerational equity. (author)

  14. Integration time for the perception of depth from motion parallax.

    Nawrot, Mark; Stroyan, Keith

    2012-04-15

    The perception of depth from relative motion is believed to be a slow process that "builds-up" over a period of observation. However, in the case of motion parallax, the potential accuracy of the depth estimate suffers as the observer translates during the viewing period. Our recent quantitative model for the perception of depth from motion parallax proposes that relative object depth (d) can be determined from retinal image motion (dθ/dt), pursuit eye movement (dα/dt), and fixation distance (f) by the formula: d/f≈dθ/dα. Given the model's dynamics, it is important to know the integration time required by the visual system to recover dα and dθ, and then estimate d. Knowing the minimum integration time reveals the incumbent error in this process. A depth-phase discrimination task was used to determine the time necessary to perceive depth-sign from motion parallax. Observers remained stationary and viewed a briefly translating random-dot motion parallax stimulus. Stimulus duration varied between trials. Fixation on the translating stimulus was monitored and enforced with an eye-tracker. The study found that relative depth discrimination can be performed with presentations as brief as 16.6 ms, with only two stimulus frames providing both retinal image motion and the stimulus window motion for pursuit (mean range=16.6-33.2 ms). This was found for conditions in which, prior to stimulus presentation, the eye was engaged in ongoing pursuit or the eye was stationary. A large high-contrast masking stimulus disrupted depth-discrimination for stimulus presentations less than 70-75 ms in both pursuit and stationary conditions. This interval might be linked to ocular-following response eye-movement latencies. We conclude that neural mechanisms serving depth from motion parallax generate a depth estimate much more quickly than previously believed. We propose that additional sluggishness might be due to the visual system's attempt to determine the maximum dθ/dα ratio

  15. Eurasia: The Rivalry of Global Integration Projects

    Olesia Kobenko

    2016-05-01

    Full Text Available The article reveals the Eurasian integration projects as major drivers of world globalization. Eurasian regionalism seems to be gaining attention in the scientific literature. Under the current political circumstance many regions are accelerating integration and many countries are opting for regional associations as a mechanism to help them overcome the global recession. Moreover, the global political leaders , some developed countries - the U.S., China, and the European Union (EU are interested to set up regional economic blocs such as Eurasian Economic Union (The EEU, the China's project 'One Belt One Road', the U.S's projects - The Trans-Pacific Partnership (TPP and The Transatlantic Trade and Investment Partnership (TTIP. The goal of this paper is to introduce a number of integration initiatives and to analyze the current strategies of Eurasian regionalism.

  16. Integrals of Motion for Discrete-Time Optimal Control Problems

    Torres, Delfim F. M.

    2003-01-01

    We obtain a discrete time analog of E. Noether's theorem in Optimal Control, asserting that integrals of motion associated to the discrete time Pontryagin Maximum Principle can be computed from the quasi-invariance properties of the discrete time Lagrangian and discrete time control system. As corollaries, results for first-order and higher-order discrete problems of the calculus of variations are obtained.

  17. General Nth order integrals of motion in the Euclidean plane

    Post, S; Winternitz, P

    2015-01-01

    The general form of an integral of motion that is a polynomial of order N in the momenta is presented for a Hamiltonian system in two-dimensional Euclidean space. The classical and the quantum cases are treated separately, emphasizing both the similarities and the differences between the two. The main application will be to study Nth order superintegrable systems that allow separation of variables in the Hamilton–Jacobi and Schrödinger equations, respectively. (paper)

  18. Global change integrating factors: Tropical tropopause trends

    Reck, R.A.

    1994-01-01

    This research proposes new criteria, shifts in the height and temperature of the tropical tropopause, as measures of global climate change. The search for signs of global warming in the temperature signal near the earth's surface is extremely difficult, largely because numerous factors contribute to surface temperature forcing with only a small signal-to-noise ratio relative to long-term effects. In the long term, no part of the atmosphere can be considered individually because the evolution will be a function of all states of all portions. A large surface greenhouse signal might ultimately be expected, but the analysis of surface temperature may not be particularly useful for early detection. What is suggested here is not an analysis of trends in the surface temperature field or any of its spatial averages, but rather an integrating factor or integrator, a single measure of global change that could be considered a test of significant change for the entire global system. Preferably, this global change integrator would vary slowly and would take into account many of the causes of climate change, with a relatively large signal-to-noise ratio. Such an integrator could be monitored, and abrupt or accelerated changes could serve as an early warning signal for policy makers and the public. Earlier work has suggested that temperature has much less short-term and small-scale noise in the lower stratosphere, and thus the global warming signal at that level might be more easily deconvoluted, because the cooling rate near the 200-mb level is almost constant with latitude. A study of the temperature signal at this pressure level might show a clearer trend due to increased levels of greenhouse gases, but it would yield information about the troposphere only by inference

  19. Hardware architecture design of a fast global motion estimation method

    Liang, Chaobing; Sang, Hongshi; Shen, Xubang

    2015-12-01

    VLSI implementation of gradient-based global motion estimation (GME) faces two main challenges: irregular data access and high off-chip memory bandwidth requirement. We previously proposed a fast GME method that reduces computational complexity by choosing certain number of small patches containing corners and using them in a gradient-based framework. A hardware architecture is designed to implement this method and further reduce off-chip memory bandwidth requirement. On-chip memories are used to store coordinates of the corners and template patches, while the Gaussian pyramids of both the template and reference frame are stored in off-chip SDRAMs. By performing geometric transform only on the coordinates of the center pixel of a 3-by-3 patch in the template image, a 5-by-5 area containing the warped 3-by-3 patch in the reference image is extracted from the SDRAMs by burst read. Patched-based and burst mode data access helps to keep the off-chip memory bandwidth requirement at the minimum. Although patch size varies at different pyramid level, all patches are processed in term of 3x3 patches, so the utilization of the patch-processing circuit reaches 100%. FPGA implementation results show that the design utilizes 24,080 bits on-chip memory and for a sequence with resolution of 352x288 and frequency of 60Hz, the off-chip bandwidth requirement is only 3.96Mbyte/s, compared with 243.84Mbyte/s of the original gradient-based GME method. This design can be used in applications like video codec, video stabilization, and super-resolution, where real-time GME is a necessity and minimum memory bandwidth requirement is appreciated.

  20. Rapid and coordinated processing of global motion images by local clusters of retinal ganglion cells.

    Matsumoto, Akihiro; Tachibana, Masao

    2017-01-01

    Even when the body is stationary, the whole retinal image is always in motion by fixational eye movements and saccades that move the eye between fixation points. Accumulating evidence indicates that the brain is equipped with specific mechanisms for compensating for the global motion induced by these eye movements. However, it is not yet fully understood how the retina processes global motion images during eye movements. Here we show that global motion images evoke novel coordinated firing in retinal ganglion cells (GCs). We simultaneously recorded the firing of GCs in the goldfish isolated retina using a multi-electrode array, and classified each GC based on the temporal profile of its receptive field (RF). A moving target that accompanied the global motion (simulating a saccade following a period of fixational eye movements) modulated the RF properties and evoked synchronized and correlated firing among local clusters of the specific GCs. Our findings provide a novel concept for retinal information processing during eye movements.

  1. Synchronization and collective motion of globally coupled Brownian particles

    Sevilla, Francisco J; Heiblum-Robles, Alexandro; Dossetti, Victor

    2014-01-01

    In this work, we study a system of passive Brownian (non-self-propelled) particles in two dimensions, interacting only through a social-like force (velocity alignment in this case) that resembles Kuramoto's coupling among phase oscillators. We show that the kinematical stationary states of the system go from a phase in thermal equilibrium with no net flux of particles, to far-from-equilibrium phases exhibiting collective motion by increasing the coupling among particles. The mechanism that leads to the instability of the equilibrium phase relies on the competition between two time scales, namely, the mean collision time of the Brownian particles in a thermal bath and the time it takes for a particle to orient its direction of motion along the direction of motion of the group. Our results show a clear connection between collective motion and the Kuramoto model for synchronization, in our case, for the direction of motion of the particles. (paper)

  2. Economic Globalization - a Phenomenon of Global Business Integration

    Radu-Marcel Joia

    2012-05-01

    Full Text Available Tumultuous economic life led scientists to seek explanations to the negative economic events,events that take many forms, and to whom it is a must to find a solution or even a mitigating factor. Thefoundation of the economy has undergone many changes. The recent events manifested in the world economyshow that the underlying fundamentals of this science must be revised because they proved to be wrong. Itnotes several times, mainly due to present economic crisis, that currently the economics have no theoreticaland practical means and no tools of analysis and intervention in the economy, proving that the existing onesare exceeded and insufficient, so that the creation of an unifying principle and of some generalizing conceptsthat could systematize and forecast the current economic phenomena in the microeconomics andmacroeconomics, especially in the transnational companies field, those which are the base of the foreigndirect investment flows, should become the main objective of the new economic science. Through this paper,we tried to illustrate the important aspects of economic globalization, the challenges that this phenomenonposes to economies and the way in which an economy can become globally competitive, under massiveconstraints of the global competition, how a national company can become globally integrated, study basedon representative references.

  3. Action Video Games Improve Direction Discrimination of Parafoveal Translational Global Motion but Not Reaction Times.

    Pavan, Andrea; Boyce, Matthew; Ghin, Filippo

    2016-10-01

    Playing action video games enhances visual motion perception. However, there is psychophysical evidence that action video games do not improve motion sensitivity for translational global moving patterns presented in fovea. This study investigates global motion perception in action video game players and compares their performance to that of non-action video game players and non-video game players. Stimuli were random dot kinematograms presented in the parafovea. Observers discriminated the motion direction of a target random dot kinematogram presented in one of the four visual quadrants. Action video game players showed lower motion coherence thresholds than the other groups. However, when the task was performed at threshold, we did not find differences between groups in terms of distributions of reaction times. These results suggest that action video games improve visual motion sensitivity in the near periphery of the visual field, rather than speed response. © The Author(s) 2016.

  4. Global motion perception is associated with motor function in 2-year-old children.

    Thompson, Benjamin; McKinlay, Christopher J D; Chakraborty, Arijit; Anstice, Nicola S; Jacobs, Robert J; Paudel, Nabin; Yu, Tzu-Ying; Ansell, Judith M; Wouldes, Trecia A; Harding, Jane E

    2017-09-29

    The dorsal visual processing stream that includes V1, motion sensitive area V5 and the posterior parietal lobe, supports visually guided motor function. Two recent studies have reported associations between global motion perception, a behavioural measure of processing in V5, and motor function in pre-school and school aged children. This indicates a relationship between visual and motor development and also supports the use of global motion perception to assess overall dorsal stream function in studies of human neurodevelopment. We investigated whether associations between vision and motor function were present at 2 years of age, a substantially earlier stage of development. The Bayley III test of Infant and Toddler Development and measures of vision including visual acuity (Cardiff Acuity Cards), stereopsis (Lang stereotest) and global motion perception were attempted in 404 2-year-old children (±4 weeks). Global motion perception (quantified as a motion coherence threshold) was assessed by observing optokinetic nystagmus in response to random dot kinematograms of varying coherence. Linear regression revealed that global motion perception was modestly, but statistically significantly associated with Bayley III composite motor (r 2 =0.06, Pmotor scores (r 2 =0.06, pmotor and fine motor scores, but unaided visual acuity was not statistically significantly associated with any of the motor scores. These results demonstrate that global motion perception and binocular vision are associated with motor function at an early stage of development. Global motion perception can be used as a partial measure of dorsal stream function from early childhood. Copyright © 2017 Elsevier B.V. All rights reserved.

  5. Cloud motions on Venus - Global structure and organization

    Limaye, S. S.; Suomi, V. E.

    1981-01-01

    Results on cloud motions on Venus obtained over a period of 3.5 days from Mariner 10 television images are presented. The implied atmosphere flow is almost zonal everywhere on the visible disk, and is in the same retrograde sense as the solid planet. Objective analysis of motions suggests the presence of jet cores (-130 m/s) and organized atmospheric waves. The longitudinal mean meridional profile of the zonal component of motion of the ultraviolet features shows presence of a midlatitude jet stream (-110 m/s). The mean zonal component is -97 m/s at the equator. The mean meridional motion at most latitudes is directed toward the pole in either hemisphere and is at least an order of magnitude smaller so that the flow is nearly zonal. A tentative conclusion from the limited coverage available from Mariner 10 is that at the level of ultraviolet features mean meridional circulation is the dominant mode of poleward angular momentum transfer as opposed to the eddy circulation.

  6. Global operations networks in motion: Managing configurations and capabilities

    Slepniov, Dmitrij; Wæhrens, Brian Vejrum; Jørgensen, Claus

    2010-01-01

    In the past, the ‘Made in the World’ label, although capturing what may lie ahead, seemed awkward and futuristic. Today, it has become a reality. An ample array of global products are built up of numerous components and modules manufactured by global networks of differentiated partners rather than...... within the boundaries of one national entity. The purpose of this paper is to contribute to bridging the empirical gap in the area of global operations networks and provide insights into how they change over time. The paper is based on the cases of three Danish companies and their global operations...

  7. Global aspects of classical integrable systems

    Cushman, Richard H

    2015-01-01

    This book gives a uniquely complete description of the geometry of the energy momentum mapping of five classical integrable systems: the 2-dimensional harmonic oscillator, the geodesic flow on the 3-sphere, the Euler top, the spherical pendulum and the Lagrange top. It presents for the first time in book form a general theory of symmetry reduction which allows one to reduce the symmetries in the spherical pendulum and the Lagrange top. Also the monodromy obstruction to the existence of global action angle coordinates is calculated for the spherical pendulum and the Lagrange top. The book addresses professional mathematicians and graduate students and can be used as a textbook on advanced classical mechanics or global analysis.

  8. Globalization and Integration Processes in Europe

    Beti Godnič

    2017-03-01

    Full Text Available Research Question (RQ: In the article we highlight the issue of whether Integration processes in the European Union are only a manifestation of these Globalization processes and if there are differences in the the old member States EU (15 and the new EU member states in changed micro and macro environment? Purpose: We wanted to determine how the old member States EU (15 and the new EU member states adapt to the new circumstances and other changes in the micro and macro environment. Method: Analysing complexity of the changes of the state of economic system, and complex fundamental global processes, which have been occurred in long period of time, need to supplement the pure scientific approach with other types of research work, more holistic approach, which is commonly used in Comparative economics. We have taken such an approach in this article. Results: In the article we studied the geopolitical changes in the micro and macro environment. We found that the development in the old EU member states EU-15 and in the new EU member states is different. EU havent addopted the harmonised economic policy which will solve the »North-South« problem and cross-state cultural consensus and find a way to operate systemically in global environment. Organization: The findings can be used to support undestanding of micro and macro envirnment of the companys and contribute for better strategic planning and design of the entire supply chain. Society: The findings can contribute to better understanding of integrative processes in the EU. Limitations/Future Research: The complexity of the problem and the dynamic changes in the functioning of the global market requires in-depth studiying of changes in the micro and macro environment of logistics companie

  9. Global human capital: integrating education and population.

    Lutz, Wolfgang; KC, Samir

    2011-07-29

    Almost universally, women with higher levels of education have fewer children. Better education is associated with lower mortality, better health, and different migration patterns. Hence, the global population outlook depends greatly on further progress in education, particularly of young women. By 2050, the highest and lowest education scenarios--assuming identical education-specific fertility rates--result in world population sizes of 8.9 and 10.0 billion, respectively. Better education also matters for human development, including health, economic growth, and democracy. Existing methods of multi-state demography can quantitatively integrate education into standard demographic analysis, thus adding the "quality" dimension.

  10. Sensory Integration with Articulated Motion on a Humanoid Robot

    J. Rojas

    2005-01-01

    Full Text Available This paper describes the integration of articulated motion with auditory and visual sensory information that enables a humanoid robot to achieve certain reflex actions that mimic those of people. Reflexes such as reach-and-grasp behavior enables the robot to learn, through experience, its own state and that of the world. A humanoid robot with binaural audio input, stereo vision, and pneumatic arms and hands exhibited tightly coupled sensory-motor behaviors in four different demonstrations. The complexity of successive demonstrations was increased to show that the reflexive sensory-motor behaviors combine to perform increasingly complex tasks. The humanoid robot executed these tasks effectively and established the groundwork for the further development of hardware and software systems, sensory-motor vector-space representations, and coupling with higher-level cognition.

  11. Default Mode Dynamics for Global Functional Integration.

    Vatansever, Deniz; Menon, David K; Manktelow, Anne E; Sahakian, Barbara J; Stamatakis, Emmanuel A

    2015-11-18

    The default mode network (DMN) has been traditionally assumed to hinder behavioral performance in externally focused, goal-directed paradigms and to provide no active contribution to human cognition. However, recent evidence suggests greater DMN activity in an array of tasks, especially those that involve self-referential and memory-based processing. Although data that robustly demonstrate a comprehensive functional role for DMN remains relatively scarce, the global workspace framework, which implicates the DMN in global information integration for conscious processing, can potentially provide an explanation for the broad range of higher-order paradigms that report DMN involvement. We used graph theoretical measures to assess the contribution of the DMN to global functional connectivity dynamics in 22 healthy volunteers during an fMRI-based n-back working-memory paradigm with parametric increases in difficulty. Our predominant finding is that brain modularity decreases with greater task demands, thus adapting a more global workspace configuration, in direct relation to increases in reaction times to correct responses. Flexible default mode regions dynamically switch community memberships and display significant changes in their nodal participation coefficient and strength, which may reflect the observed whole-brain changes in functional connectivity architecture. These findings have important implications for our understanding of healthy brain function, as they suggest a central role for the DMN in higher cognitive processing. The default mode network (DMN) has been shown to increase its activity during the absence of external stimulation, and hence was historically assumed to disengage during goal-directed tasks. Recent evidence, however, implicates the DMN in self-referential and memory-based processing. We provide robust evidence for this network's active contribution to working memory by revealing dynamic reconfiguration in its interactions with other networks

  12. Integrated assessment models of global climate change

    Parson, E.A.; Fisher-Vanden, K.

    1997-01-01

    The authors review recent work in the integrated assessment modeling of global climate change. This field has grown rapidly since 1990. Integrated assessment models seek to combine knowledge from multiple disciplines in formal integrated representations; inform policy-making, structure knowledge, and prioritize key uncertainties; and advance knowledge of broad system linkages and feedbacks, particularly between socio-economic and bio-physical processes. They may combine simplified representations of the socio-economic determinants of greenhouse gas emissions, the atmosphere and oceans, impacts on human activities and ecosystems, and potential policies and responses. The authors summarize current projects, grouping them according to whether they emphasize the dynamics of emissions control and optimal policy-making, uncertainty, or spatial detail. They review the few significant insights that have been claimed from work to date and identify important challenges for integrated assessment modeling in its relationships to disciplinary knowledge and to broader assessment seeking to inform policy- and decision-making. 192 refs., 2 figs

  13. Geometrical-integrability constraints and equations of motion in four plus extended super spaces

    Chau, L.L.

    1987-01-01

    It is pointed out that many equations of motion in physics, including gravitational and Yang-Mills equations, have a common origin: i.e. they are the results of certain geometrical integrability conditions. These integrability conditions lead to linear systems and conservation laws that are important in integrating these equations of motion

  14. Quadratic integrals of motion for identical particle systems in quantum case

    Brije, I.; Gonera, S.; Kosinski, P.; Maslanka, P.; Giller, S.

    2005-01-01

    One studied quantum dynamic systems of identical particles allowing for additional integral of motion being quadratic in pulses. It was found that there was an appropriate way to ensure order that enabled to convert the classical integrals of motion into their quantum analogues. One analyzed relation of the mentioned integrals with splitting of the variables in the Schroedinger equation [ru

  15. Integrated Global Nuclear Materials Management Preliminary Concepts

    Jones, E; Dreicer, M.

    2006-01-01

    The world is at a turning point, moving away from the Cold War nuclear legacy towards a future global nuclear enterprise; and this presents a transformational challenge for nuclear materials management. Achieving safety and security during this transition is complicated by the diversified spectrum of threat 'players' that has greatly impacted nonproliferation, counterterrorism, and homeland security requirements. Rogue states and non-state actors no longer need self-contained national nuclear expertise, materials, and equipment due to availability from various sources in the nuclear market, thereby reducing the time, effort and cost for acquiring a nuclear weapon (i.e., manifestations of latency). The terrorist threat has changed the nature of military and national security requirements to protect these materials. An Integrated Global Nuclear Materials Management (IGNMM) approach would address the existing legacy nuclear materials and the evolution towards a nuclear energy future, while strengthening a regime to prevent nuclear weapon proliferation. In this paper, some preliminary concepts and studies of IGNMM will be presented. A systematic analysis of nuclear materials, activities, and controls can lead to a tractable, integrated global nuclear materials management architecture that can help remediate the past and manage the future. A systems approach is best suited to achieve multi-dimensional and interdependent solutions, including comprehensive, end-to-end capabilities; coordinated diverse elements for enhanced functionality with economy; and translation of goals/objectives or standards into locally optimized solutions. A risk-informed basis is excellent for evaluating system alternatives and performances, and it is especially appropriate for the security arena. Risk management strategies--such as defense-in-depth, diversity, and control quality--help to weave together various technologies and practices into a strong and robust security fabric. Effective

  16. Global integrability of field theories. Proceedings

    Calmet, J.; Seiler, W.M.; Tucker, R.W.

    2006-01-01

    The GIFT 2006 workshop covers topics related to the Global Integration of Field Theories. These topics span several domains of science including Mathematics, Physics and Computer Science. It is indeed an interdisciplinary event and this feature is well illustrated by the diversity of papers presented at the workshop. Physics is our main target. A simple approach would be to state that we investigate systems of partial differential equations since it is widely believed that they provide a fair description of our world. The questions whether this world is Einsteinian or not, is described by String Theory or not are not however on our agenda. At this stage we have defined what we mean with field theories. To assess what global integrability means we surf on the two other domains of our interest. Mathematics delivers the main methodologies and tools to achieve our goal. It is a trivial remark to say that there exists several approaches to investigate the concept of integrability. Only selected ones are to be found in these proceedings. We do not try to define precisely what global integrability means. Instead, we only suggest two tracks. The first one is by analogy with the design of algorithms, in Computer Algebra or Computer Science, to solve systems of differential equations. The case of ODEs is rather well understood since a constructive methodology exists. Although many experts claim that numerous results do exist to solve systems of PDEs, no constructive decision method exists. This is our first track. The second track follows directly since the real world is described by systems of PDEs, which are mainly non-linear ones. To be able to decide in such a case of the existence of solutions would increase immediately the scope of new technologies applicable to indus trial problems. It is this latter remark that led to the European NEST project with the same name. The GIFT project aims at making progresses in the investigation of field theories through the use of very

  17. Global integrability of field theories. Proceedings

    Calmet, J.; Seiler, W.M.; Tucker, R.W. (eds.)

    2006-07-01

    The GIFT 2006 workshop covers topics related to the Global Integration of Field Theories. These topics span several domains of science including Mathematics, Physics and Computer Science. It is indeed an interdisciplinary event and this feature is well illustrated by the diversity of papers presented at the workshop. Physics is our main target. A simple approach would be to state that we investigate systems of partial differential equations since it is widely believed that they provide a fair description of our world. The questions whether this world is Einsteinian or not, is described by String Theory or not are not however on our agenda. At this stage we have defined what we mean with field theories. To assess what global integrability means we surf on the two other domains of our interest. Mathematics delivers the main methodologies and tools to achieve our goal. It is a trivial remark to say that there exists several approaches to investigate the concept of integrability. Only selected ones are to be found in these proceedings. We do not try to define precisely what global integrability means. Instead, we only suggest two tracks. The first one is by analogy with the design of algorithms, in Computer Algebra or Computer Science, to solve systems of differential equations. The case of ODEs is rather well understood since a constructive methodology exists. Although many experts claim that numerous results do exist to solve systems of PDEs, no constructive decision method exists. This is our first track. The second track follows directly since the real world is described by systems of PDEs, which are mainly non-linear ones. To be able to decide in such a case of the existence of solutions would increase immediately the scope of new technologies applicable to indus trial problems. It is this latter remark that led to the European NEST project with the same name. The GIFT project aims at making progresses in the investigation of field theories through the use of very

  18. Alterations to global but not local motion processing in long-term ecstasy (MDMA) users.

    White, Claire; Brown, John; Edwards, Mark

    2014-07-01

    Growing evidence indicates that the main psychoactive ingredient in the illegal drug "ecstasy" (methylendioxymethamphetamine) causes reduced activity in the serotonin and gamma-aminobutyric acid (GABA) systems in humans. On the basis of substantial serotonin input to the occipital lobe, recent research investigated visual processing in long-term users and found a larger magnitude of the tilt aftereffect, interpreted to reflect broadened orientation tuning bandwidths. Further research found higher orientation discrimination thresholds and reduced long-range interactions in the primary visual area of ecstasy users. The aim of the present research was to investigate whether serotonin-mediated V1 visual processing deficits in ecstasy users extend to motion processing mechanisms. Forty-five participants (21 controls, 24 drug users) completed two psychophysical studies: A direction discrimination study directly measured local motion processing in V1, while a motion coherence task tested global motion processing in area V5/MT. "Primary" ecstasy users (n = 18), those without substantial polydrug use, had significantly lower global motion thresholds than controls [p = 0.027, Cohen's d = 0.78 (large)], indicating increased sensitivity to global motion stimuli, but no difference in local motion processing (p = 0.365). These results extend on previous research investigating the long-term effects of illicit drugs on visual processing. Two possible explanations are explored: defuse attentional processes may be facilitating spatial pooling of motion signals in users. Alternatively, it may be that a GABA-mediated disruption to V5/MT processing is reducing spatial suppression and therefore improving global motion perception in ecstasy users.

  19. Motion and Emotion: The Global Appeal of Axiomatic Metaphors

    Børch, Marianne

    2013-01-01

    of verbal meaning: Durand distinguishes between words and images, argues that certain images are pre-conceptual and pre-linguistic, and concludes that such signs have inherent, not merely differential, meaning. Finally, the genre of romance—in modern terms fantasy or magic realism—may convey globally shared...

  20. Global plastic surgeons images depicted in motion pictures.

    Hwang, Se Jin; Park, Sowhey; Hwang, Kun

    2013-03-01

    Motion pictures are made to entertain and enlighten people, but they are viewed differently by different people. What one considers to be a tearjerker may induce giggles in another. We have gained added interest in this because our professional pictures contain plastic surgery in their venue. We have recently reviewed 21 motion pictures that were made from 1928 to 2006 and that includes plastic surgical procedures in their content. As a habit, we tried to analyze them from a surgical point of view. About one third (35.7%) of the patients were criminals, whereas 14.3% of them were spies. One third of the procedures were done by illegitimate "surgeons," whereas a quarter of the procedures (25%) were performed by renowned surgeons. Surgeons who were in love with the patients did the rest (25%) of the operations. The complication rate was 14.3%; the surgery was successful in 85.7% of cases, but were the patients happy with the results? This was not the case in the movies. Only 7.7% were happy; 14.5 % of them were eminently unhappy. Why the discrepancy? It is difficult to analyze the minds of the people in the film, but considering that the majority of the characters in the films were rather unsavory, one may deduce that a crooked mind functions differently. Motion pictures have advanced greatly in the past several decades with the advent of improved mechanical and electronic devices, and plastic surgery as also advanced in tandem. This surgical field has become a common procedure in our daily life. It is readily available and mostly painless. However, the public sees it in only one way, that is, that the performing physicians are highly compensated. Very few consider the efforts and the suffering that accompanies each and every surgical procedure as it is performed. Perhaps, it is too much to hope for a day that will come when we will see a film that portrays the mental anguish that accompanies each and every procedure the plastic surgeon makes.

  1. Global optimization for motion estimation with applications to ultrasound videos of carotid artery plaques

    Murillo, Sergio; Pattichis, Marios; Soliz, Peter; Barriga, Simon; Loizou, C. P.; Pattichis, C. S.

    2010-03-01

    Motion estimation from digital video is an ill-posed problem that requires a regularization approach. Regularization introduces a smoothness constraint that can reduce the resolution of the velocity estimates. The problem is further complicated for ultrasound videos (US), where speckle noise levels can be significant. Motion estimation using optical flow models requires the modification of several parameters to satisfy the optical flow constraint as well as the level of imposed smoothness. Furthermore, except in simulations or mostly unrealistic cases, there is no ground truth to use for validating the velocity estimates. This problem is present in all real video sequences that are used as input to motion estimation algorithms. It is also an open problem in biomedical applications like motion analysis of US of carotid artery (CA) plaques. In this paper, we study the problem of obtaining reliable ultrasound video motion estimates for atherosclerotic plaques for use in clinical diagnosis. A global optimization framework for motion parameter optimization is presented. This framework uses actual carotid artery motions to provide optimal parameter values for a variety of motions and is tested on ten different US videos using two different motion estimation techniques.

  2. Plate Motion and Crustal Deformation Estimated with Geodetic Data from the Global Positioning System

    Argus, Donald F.; Heflin, Michael B.

    1995-01-01

    We use geodetic data taken over four years with the Global Positioning System (GPS) to estimate: (1) motion between six major plates and (2) motion relative to these plates of ten sites in plate boundary zones. The degree of consistency between geodetic velocities and rigid plates requires the (one-dimensional) standard errors in horizontal velocities to be approx. 2 mm/yr. Each of the 15 angular velocities describing motion between plate pairs that we estimate with GPS differs insignificantly from the corresponding angular velocity in global plate motion model NUVEL-1A, which averages motion over the past 3 m.y. The motion of the Pacific plate relative to both the Eurasian and North American plates is observed to be faster than predicted by NUVEL-1A, supporting the inference from Very Long B ase- line Interferometry (VLBI) that motion of the Pacific plate has speed up over the past few m.y. The Eurasia-North America pole of rotation is estimated to be north of NUVEL-1A, consistent with the independent hypothesis that the pole has recently migrated northward across northeast Asia to near the Lena River delta. Victoria, which lies above the main thrust at the Cascadia subduction zone, moves relative to the interior of the overriding plate at 30% of the velocity of the subducting plate, reinforcing the conclusion that the thrust there is locked beneath the continental shelf and slope.

  3. Integration Method of Emphatic Motions and Adverbial Expressions with Scalar Parameters for Robotic Motion Coaching System

    Okuno, Keisuke; Inamura, Tetsunari

    A robotic coaching system can improve humans' learning performance of motions by intelligent usage of emphatic motions and adverbial expressions according to user reactions. In robotics, however, method to control both the motions and the expressions and how to bind them had not been adequately discussed from an engineering point of view. In this paper, we propose a method for controlling and binding emphatic motions and adverbial expressions by using two scalar parameters in a phase space. In the phase space, variety of motion patterns and verbal expressions are connected and can be expressed as static points. We show the feasibility of the proposing method through experiments of actual sport coaching tasks for beginners. From the results of participants' improvements in motion learning, we confirmed the feasibility of the methods to control and bind emphatic motions and adverbial expressions, as well as confirmed contribution of the emphatic motions and positive correlation of adverbial expressions for participants' improvements in motion learning. Based on the results, we introduce a hypothesis that individually optimized method for binding adverbial expression is required.

  4. Circuit Mechanisms Governing Local vs. Global Motion Processing in Mouse Visual Cortex

    Rasmussen, Rune; Yonehara, Keisuke

    2017-01-01

    components represented by component direction-selective (CDS) cells. However, how PDS and CDS cells develop their distinct response properties is still unresolved. The visual cortex of the mouse is an attractive model for experimentally solving this issue due to the large molecular and genetic toolbox...... literature on global motion processing based on works in primates and mice. Lastly, we propose what types of experiments could illuminate what circuit mechanisms are governing cortical global visual motion processing. We propose that PDS cells in mouse visual cortex appear as the perfect arena...

  5. Toward an Integrative Model of Global Business Strategy

    Li, Xin

    fragmentation-integration-fragmentation-integration upward spiral. In response to the call for integrative approach to strategic management research, we propose an integrative model of global business strategy that aims at integrating not only strategy and IB but also the different paradigms within the strategy...... field. We also discuss the merit and limitation of our model....

  6. Neurons Responsive to Global Visual Motion Have Unique Tuning Properties in Hummingbirds.

    Gaede, Andrea H; Goller, Benjamin; Lam, Jessica P M; Wylie, Douglas R; Altshuler, Douglas L

    2017-01-23

    Neurons in animal visual systems that respond to global optic flow exhibit selectivity for motion direction and/or velocity. The avian lentiformis mesencephali (LM), known in mammals as the nucleus of the optic tract (NOT), is a key nucleus for global motion processing [1-4]. In all animals tested, it has been found that the majority of LM and NOT neurons are tuned to temporo-nasal (back-to-front) motion [4-11]. Moreover, the monocular gain of the optokinetic response is higher in this direction, compared to naso-temporal (front-to-back) motion [12, 13]. Hummingbirds are sensitive to small visual perturbations while hovering, and they drift to compensate for optic flow in all directions [14]. Interestingly, the LM, but not other visual nuclei, is hypertrophied in hummingbirds relative to other birds [15], which suggests enhanced perception of global visual motion. Using extracellular recording techniques, we found that there is a uniform distribution of preferred directions in the LM in Anna's hummingbirds, whereas zebra finch and pigeon LM populations, as in other tetrapods, show a strong bias toward temporo-nasal motion. Furthermore, LM and NOT neurons are generally classified as tuned to "fast" or "slow" motion [10, 16, 17], and we predicted that most neurons would be tuned to slow visual motion as an adaptation for slow hovering. However, we found the opposite result: most hummingbird LM neurons are tuned to fast pattern velocities, compared to zebra finches and pigeons. Collectively, these results suggest a role in rapid responses during hovering, as well as in velocity control and collision avoidance during forward flight of hummingbirds. Copyright © 2017 Elsevier Ltd. All rights reserved.

  7. Global Environmental Change: An integrated modelling approach

    Den Elzen, M.

    1993-01-01

    Two major global environmental problems are dealt with: climate change and stratospheric ozone depletion (and their mutual interactions), briefly surveyed in part 1. In Part 2 a brief description of the integrated modelling framework IMAGE 1.6 is given. Some specific parts of the model are described in more detail in other Chapters, e.g. the carbon cycle model, the atmospheric chemistry model, the halocarbon model, and the UV-B impact model. In Part 3 an uncertainty analysis of climate change and stratospheric ozone depletion is presented (Chapter 4). Chapter 5 briefly reviews the social and economic uncertainties implied by future greenhouse gas emissions. Chapters 6 and 7 describe a model and sensitivity analysis pertaining to the scientific uncertainties and/or lacunae in the sources and sinks of methane and carbon dioxide, and their biogeochemical feedback processes. Chapter 8 presents an uncertainty and sensitivity analysis of the carbon cycle model, the halocarbon model, and the IMAGE model 1.6 as a whole. Part 4 presents the risk assessment methodology as applied to the problems of climate change and stratospheric ozone depletion more specifically. In Chapter 10, this methodology is used as a means with which to asses current ozone policy and a wide range of halocarbon policies. Chapter 11 presents and evaluates the simulated globally-averaged temperature and sea level rise (indicators) for the IPCC-1990 and 1992 scenarios, concluding with a Low Risk scenario, which would meet the climate targets. Chapter 12 discusses the impact of sea level rise on the frequency of the Dutch coastal defence system (indicator) for the IPCC-1990 scenarios. Chapter 13 presents projections of mortality rates due to stratospheric ozone depletion based on model simulations employing the UV-B chain model for a number of halocarbon policies. Chapter 14 presents an approach for allocating future emissions of CO 2 among regions. (Abstract Truncated)

  8. Integrated Water Resources Management: A Global Review

    Srinivasan, V.; Cohen, M.; Akudago, J.; Keith, D.; Palaniappan, M.

    2011-12-01

    The diversity of water resources endowments and the societal arrangements to use, manage, and govern water makes defining a single paradigm or lens through which to define, prioritize and evaluate interventions in the water sector particularly challenging. Integrated Water Resources Management (IWRM) emerged as the dominant intervention paradigm for water sector interventions in the early 1990s. Since then, while many successful implementations of IWRM have been demonstrated at the local, basin, national and trans-national scales, IWRM has also been severely criticized by the global water community as "having a dubious record that has never been comprehensively analyzed", "curiously ambiguous", and "ineffective at best and counterproductive at worst". Does IWRM hold together as a coherent paradigm or is it a convenient buzzword to describe a diverse collection of water sector interventions? We analyzed 184 case study summaries of IWRM interventions on the Global Water Partnership (GWP) website. The case studies were assessed to find the nature, scale, objectives and outcomes of IWRM. The analysis does not suggest any coherence in IWRM as a paradigm - but does indicate distinct regional trends in IWRM. First, IWRM was done at very different scales in different regions. In Africa two-thirds of the IWRM interventions involved creating national or transnational organizations. In contrast, in Asia and South America, almost two-thirds were watershed, basin, or local body initiatives. Second, IWRM interventions involved very different types of activities in different regions. In Africa and Europe, IWRM entailed creation of policy documents, basin plans and institution building. In contrast, in Asia and Latin America the interventions were much more likely to entail new technology, infrastructure or watershed measures. In Australia, economic measures, new laws and enforcement mechanisms were more commonly used than anywhere else.

  9. Predicting 2D target velocity cannot help 2D motion integration for smooth pursuit initiation.

    Montagnini, Anna; Spering, Miriam; Masson, Guillaume S

    2006-12-01

    Smooth pursuit eye movements reflect the temporal dynamics of bidimensional (2D) visual motion integration. When tracking a single, tilted line, initial pursuit direction is biased toward unidimensional (1D) edge motion signals, which are orthogonal to the line orientation. Over 200 ms, tracking direction is slowly corrected to finally match the 2D object motion during steady-state pursuit. We now show that repetition of line orientation and/or motion direction does not eliminate the transient tracking direction error nor change the time course of pursuit correction. Nonetheless, multiple successive presentations of a single orientation/direction condition elicit robust anticipatory pursuit eye movements that always go in the 2D object motion direction not the 1D edge motion direction. These results demonstrate that predictive signals about target motion cannot be used for an efficient integration of ambiguous velocity signals at pursuit initiation.

  10. Developing a Global Mindset: Integrating Demographics, Sustainability, Technology, and Globalization

    Aggarwal, Raj

    2011-01-01

    Business schools face a number of challenges in responding to the business influences of demographics, sustainability, and technology--all three of which are also the fundamental driving forces for globalization. Demographic forces are creating global imbalances in worker populations and in government finances; the world economy faces…

  11. On Integral Invariants for Effective 3-D Motion Trajectory Matching and Recognition.

    Shao, Zhanpeng; Li, Youfu

    2016-02-01

    Motion trajectories tracked from the motions of human, robots, and moving objects can provide an important clue for motion analysis, classification, and recognition. This paper defines some new integral invariants for a 3-D motion trajectory. Based on two typical kernel functions, we design two integral invariants, the distance and area integral invariants. The area integral invariants are estimated based on the blurred segment of noisy discrete curve to avoid the computation of high-order derivatives. Such integral invariants for a motion trajectory enjoy some desirable properties, such as computational locality, uniqueness of representation, and noise insensitivity. Moreover, our formulation allows the analysis of motion trajectories at a range of scales by varying the scale of kernel function. The features of motion trajectories can thus be perceived at multiscale levels in a coarse-to-fine manner. Finally, we define a distance function to measure the trajectory similarity to find similar trajectories. Through the experiments, we examine the robustness and effectiveness of the proposed integral invariants and find that they can capture the motion cues in trajectory matching and sign recognition satisfactorily.

  12. Metadata-Assisted Global Motion Estimation for Medium-Altitude Unmanned Aerial Vehicle Video Applications

    Hongguang Li

    2015-09-01

    Full Text Available Global motion estimation (GME is a key technology in unmanned aerial vehicle remote sensing (UAVRS. However, when a UAV’s motion and behavior change significantly or the image information is not rich, traditional image-based methods for GME often perform poorly. Introducing bottom metadata can improve precision in a large-scale motion condition and reduce the dependence on unreliable image information. GME is divided into coarse and residual GME through coordinate transformation and based on the study hypotheses. In coarse GME, an auxiliary image is built to convert image matching from a wide baseline condition to a narrow baseline one. In residual GME, a novel information and contrast feature detection algorithm is proposed for big-block matching to maximize the use of reliable image information and ensure that the contents of interest are well estimated. Additionally, an image motion monitor is designed to select the appropriate processing strategy by monitoring the motion scales of translation, rotation, and zoom. A medium-altitude UAV is employed to collect three types of large-scale motion datasets. Peak signal to noise ratio (PSNR and motion scale are computed. This study’s result is encouraging and applicable to other medium- or high-altitude UAVs with a similar system structure.

  13. Impact of bulk atmospheric motion on local and global containment heat transfer

    Green, J.A.; Almenas, K.

    1995-01-01

    Local and global correlations for condensing energy transfer in the presence of noncondensable gases in a containment facility have been evaluated. The database employed stems from the E11.2 and E11.4 tests conducted at the German HDR facility. The HDR containment is a 11060-ml, 60-m-high decommissioned light water reactor. The tests simulated long-term (up to 56 h) accident conditions. Numerous instrumented structural blocks (concrete and lead) were located throughout the containment to provide detailed local heat transfer measurements. These data represent what is probably the most extensive database of integral energy transfer measurements available. It is well established that the major resistance to condensation heat transfer in the presence of noncondensable gases is a gaseous boundary layer that builds up in front of the condensing surface. Correlations that seek to model heat transfer for these conditions should depend on parameters that most strongly determine the buildup and thickness of this boundary layer. Two of the most important parameters are the vapor/noncondensable concentration ratio and the local atmospheric motion. Secondary parameters include the atmosphere-to-surface temperature difference, the pressure, and condensing surface properties. The HDR tests are unique in terms of the quantity and variety of instrumentation employed. However, one of the most important parameters, the local bulk atmospheric velocity, is inherently difficult to measure, and only fragmentary measurements are available even in the HDR data-base. A detailed analysis of these data is presented by Green. This study uses statistical methods to evaluate local and global empirical correlations that do not include the atmospheric velocity. The magnitude of the differences between the correlations emphasizes the importance of the local atmospheric velocity and serves to illustrate the accuracy limits of correlations that neglect this essential parameter

  14. Integrated Task and Motion Planning with Verification via Formal Methods

    National Aeronautics and Space Administration — This proposal lays out a research plan to "lift" current state-of-the-art results combining discrete and continuous layers of planning in motion planning to the more...

  15. Isolating integrals of the motion for stellar orbits in a rotating galactic bar

    Vandervoort, P.O.

    1979-01-01

    The study of the equilibrium of a rotating galactic bar requires an enumeration of the isolating integrals of the motion of a star in the prevailing gravitational field. In general, Jacobi's integral is the only exact isolating integral known. This paper describes a search for an additional isolating integral for orbits confined to a plane perpendicular to the axis of the bar's rotation. It is shown that, in general, the equations of motion admit an additional integral exactly which is a nonhomogeneous quadratic form in the momenta of the star only if (1) the gravitational potential is axisymmetric, (2) the gravitational potential is harmonic, or (3) the bar does not rotate and the gravitational potential is separable in elliptic coordinates. A formal integral of the motion is constructed for orbits in a slightly anharmonic potential. Numerical solutions of the equations of motion for orbits in a slightly anharmonic potential behave as if there were indeed an additional isolating integral, and that behavior is represented very well in terms of the formal integral. If the rotation of the bar is rapid and/or the nonaxisymmetry of the bar is weak, then the additional integral restricts the motion of a star in much the same way that the angular momentum restricts motion in an axisymmetric potential. Conversely, if the rotation of the bar is slow and/or the nonaxisymmetry of the bar is strong, then the additional integral restricts the motion in much the same way that the difference of the separable energies would if the motion were separable in Cartesian coordinates

  16. A review of some basic aspects related to integration of airplane’s equations of motion

    Dan TURCANU

    2017-09-01

    Full Text Available Numerical integration of the airplane’s equations of motion has long been considered among the most fundamental calculations in airplane’s analysis. Numerical algorithms have been implemented and experimentally validated. However, the need for superior speed and accuracy is still very topical, as, nowadays, various optimization algorithms rely heavily on data generated from the integration of the equations of motion and having access to larger amounts of data can increase the quality of the optimization. Now, for a number of decades, engineers have relied heavily on commercial codes based on automatically selected integration steps. However, optimally chosen constant integration steps can save time and allows for larger numbers of integrations to be performed. Yet, the basic papers that presented the fundamentals of numerical integration, as applied to airplane’s equations of motion are nowadays not easy to locate. Consequently, this paper presents a review of basic aspects related to the integration of airplane’s equation of motion. The discussion covers fundamentals of longitudinal and lateral-directional motion as well as the implementation of some numerical integration methods. The relation between numerical integration steps, accuracy, computational resource usage, numerical stability and their relation with the parameters describing the dynamic response of the airplane is considered and suggestions are presented for a faster yet accurate numerical integration.

  17. Global integrability of cosmological scalar fields

    Maciejewski, Andrzej J.; Przybylska, Maria; Stachowiak, Tomasz; Szydłowski, Marek

    2008-11-01

    We investigate the Liouvillian integrability of Hamiltonian systems describing a universe filled with a scalar field (possibly complex). The tool used is the differential Galois group approach, as introduced by Morales-Ruiz and Ramis. The main result is that the generic systems with minimal coupling are non-integrable, although there still exist some values of parameters for which integrability remains undecided; the conformally coupled systems are only integrable in four known cases. We also draw a connection with the chaos present in such cosmological models, and the issues of the integrability restricted to the real domain.

  18. Global integrability of cosmological scalar fields

    Maciejewski, Andrzej J; Przybylska, Maria; Stachowiak, Tomasz; Szydlowski, Marek

    2008-01-01

    We investigate the Liouvillian integrability of Hamiltonian systems describing a universe filled with a scalar field (possibly complex). The tool used is the differential Galois group approach, as introduced by Morales-Ruiz and Ramis. The main result is that the generic systems with minimal coupling are non-integrable, although there still exist some values of parameters for which integrability remains undecided; the conformally coupled systems are only integrable in four known cases. We also draw a connection with the chaos present in such cosmological models, and the issues of the integrability restricted to the real domain

  19. Integrals of the motion and exact solutions of the problem of two dispersing delta-wells

    Man'ko, V.I.; Chikhachev, A.S.

    1998-01-01

    An exact solution is analyzed for the analogs of bound and scattering states in a nonstationary quantum mechanical system whose potential has the form of two dispersing delta-wells. For the delta-potentials explicit (in the form of operator kernels) expressions are found for the integrals of the motion that depend on time and transform to the known integrals of the motion for a free quantum particle as the interaction force with the potential approaches zero

  20. Global design of an active integrated antenna for millimeter wave

    Marzolf, Eric; Drissi, M’hamed

    2001-01-01

    An active integrated antenna working in the millimeter wave has been realized in a monolithic process. The concept of active integrated antenna is first introduced, then the design of the integrated circuit based on a global approach, following electromagnetic and circuit simulations, is presented. The obtained performances of the active antenna are discussed and compared to a passive one.

  1. A globally integrated climate policy for Canada

    Bernstein, S.; Brunnee, J.; Duff, D.G.; Green, A.J.

    2008-01-01

    This book explored policy ideas and options from various perspectives, including science, law, political science, economics and sociology. The costs, opportunities and imperatives to participate in international diplomatic initiatives were considered along with the opportunities of regional global carbon markets. Canada's current policy on climate change negotiations have been focused on domestic regulation and incentives for technological responses and the setting of a domestic carbon price. The sense of urgency about global warming was discussed and the need for action to respond to the threat of global climate change was emphasized. The book also reviewed Canada's role in international climate policies and presented parameters and imperatives for global regime building in Canada. Domestic policy tools were also reviewed along with policy obstacles and opportunities. refs., tabs., figs.

  2. Visualizing Stable Features in Live Cell Nucleus for Evaluation of the Cell Global Motion Compensation

    Sorokin, D.V.; Suchánková, Jana; Bártová, Eva; Matula, P.

    2014-01-01

    Roč. 60, č. 1 (2014), s. 45-49 ISSN 0015-5500 R&D Projects: GA ČR GBP302/12/G157; GA MŠk(CZ) EE2.3.30.0030 Institutional support: RVO:68081707 Keywords : cell global motion compensation * UV laser bleaching * image registration Subject RIV: BO - Biophysics Impact factor: 1.000, year: 2014

  3. Approximate Integrals of rf-driven Particle Motion in Magnetic Field

    Dodin, I.Y.; Fisch, N.J.

    2004-01-01

    For a particle moving in nonuniform magnetic field under the action of an rf wave, ponderomotive effects result from rf-driven oscillations nonlinearly coupled with Larmor rotation. Using Lagrangian and Hamiltonian formalism, we show how, despite this coupling, two independent integrals of the particle motion are approximately conserved. Those are the magnetic moment of free Larmor rotation and the quasi-energy of the guiding center motion parallel to the magnetic field. Under the assumption of non-resonant interaction of the particle with the rf field, these integrals represent adiabatic invariants of the particle motion

  4. INS/GNSS Integration for Aerobatic Flight Applications and Aircraft Motion Surveying.

    V Hinüber, Edgar L; Reimer, Christian; Schneider, Tim; Stock, Michael

    2017-04-26

    This paper presents field tests of challenging flight applications obtained with a new family of lightweight low-power INS/GNSS ( inertial navigation system/global satellite navigation system ) solutions based on MEMS ( micro-electro-mechanical- sensor ) machined sensors, being used for UAV ( unmanned aerial vehicle ) navigation and control as well as for aircraft motion dynamics analysis and trajectory surveying. One key is a 42+ state extended Kalman-filter-based powerful data fusion, which also allows the estimation and correction of parameters that are typically affected by sensor aging, especially when applying MEMS-based inertial sensors, and which is not yet deeply considered in the literature. The paper presents the general system architecture, which allows iMAR Navigation the integration of all classes of inertial sensors and GNSS ( global navigation satellite system ) receivers from very-low-cost MEMS and high performance MEMS over FOG ( fiber optical gyro ) and RLG ( ring laser gyro ) up to HRG ( hemispherical resonator gyro ) technology, and presents detailed flight test results obtained under extreme flight conditions. As a real-world example, the aerobatic maneuvers of the World Champion 2016 (Red Bull Air Race) are presented. Short consideration is also given to surveying applications, where the ultimate performance of the same data fusion, but applied on gravimetric surveying, is discussed.

  5. Impaired global, and compensatory local, biological motion processing in people with high levels of autistic traits.

    van Boxtel, Jeroen J A; Lu, Hongjing

    2013-01-01

    People with Autism Spectrum Disorder (ASD) are hypothesized to have poor high-level processing but superior low-level processing, causing impaired social recognition, and a focus on non-social stimulus contingencies. Biological motion perception provides an ideal domain to investigate exactly how ASD modulates the interaction between low and high-level processing, because it involves multiple processing stages, and carries many important social cues. We investigated individual differences among typically developing observers in biological motion processing, and whether such individual differences associate with the number of autistic traits. In Experiment 1, we found that individuals with fewer autistic traits were automatically and involuntarily attracted to global biological motion information, whereas individuals with more autistic traits did not show this pre-attentional distraction. We employed an action adaptation paradigm in the second study to show that individuals with more autistic traits were able to compensate for deficits in global processing with an increased involvement in local processing. Our findings can be interpreted within a predictive coding framework, which characterizes the functional relationship between local and global processing stages, and explains how these stages contribute to the perceptual difficulties associated with ASD.

  6. Impaired global, and compensatory local, biological motion processing in people with high levels of autistic traits

    Jeroen J A Van Boxtel

    2013-04-01

    Full Text Available People with Autism Spectrum Disorder (ASD are hypothesized to have poor high-level processing but superior low-level processing, causing impaired social recognition, and a focus on non-social stimulus contingencies. Biological motion perception provides an ideal domain to investigate exactly how ASD modulates the interaction between low and high-level processing, because it involves multiple processing stages, and carries many important social cues. We investigated individual differences among typically developing observers in biological motion processing, and whether such individual differences associate with the number of autistic traits. In Experiment 1, we found that individuals with fewer autistic traits were automatically and involuntarily attracted to global biological motion information, whereas individuals with more autistic traits did not show this pre-attentional distraction. We employed an action adaptation paradigm in the second study to show that individuals with more autistic traits were able to compensate for deficits in global processing with an increased involvement in local processing. Our findings can be interpreted within a predictive coding framework, which characterizes the functional relationship between local and global processing stages, and explains how these stages contribute to the perceptual difficulties associated with ASD.

  7. Global format for energy-momentum based time integration in nonlinear dynamics

    Krenk, Steen

    2014-01-01

    A global format is developed for momentum and energy consistent time integration of second‐order dynamic systems with general nonlinear stiffness. The algorithm is formulated by integrating the state‐space equations of motion over the time increment. The internal force is first represented...... of mean value products at the element level or explicit use of a geometric stiffness matrix. An optional monotonic algorithmic damping, increasing with response frequency, is developed in terms of a single damping parameter. In the solution procedure, the velocity is eliminated and the nonlinear...

  8. A study on infinite number of integrals of motion in classically integrable system with boundary: Pt.1

    Chen Yixin; Luo Xudong

    1998-01-01

    By the zero curvature condition in classically integrable system, the generating functions for integrals of motion and equations for solving K +- matrices are obtained in two-dimensional integrable systems on a finite interval with independent boundary conditions on each end. Classically integrable boundary conditions will be found by solving K +- matrices. The authors develop a Hamiltonian method in classically integrable system with independent boundary conditions on each end. The result can be applied to more integrable systems than those associated with E.K. Sklyanin's approach

  9. Cervical spine motion in manual versus Jackson table turning methods in a cadaveric global instability model.

    DiPaola, Matthew J; DiPaola, Christian P; Conrad, Bryan P; Horodyski, MaryBeth; Del Rossi, Gianluca; Sawers, Andrew; Bloch, David; Rechtine, Glenn R

    2008-06-01

    A study of spine biomechanics in a cadaver model. To quantify motion in multiple axes created by transfer methods from stretcher to operating table in the prone position in a cervical global instability model. Patients with an unstable cervical spine remain at high risk for further secondary injury until their spine is adequately surgically stabilized. Previous studies have revealed that collars have significant, but limited benefit in preventing cervical motion when manually transferring patients. The literature proposes multiple methods of patient transfer, although no one method has been universally adopted. To date, no study has effectively evaluated the relationship between spine motion and various patient transfer methods to an operating room table for prone positioning. A global instability was surgically created at C5-6 in 4 fresh cadavers with no history of spine pathology. All cadavers were tested both with and without a rigid cervical collar in the intact and unstable state. Three headrest permutations were evaluated Mayfield (SM USA Inc), Prone View (Dupaco, Oceanside, CA), and Foam Pillow (OSI, Union City, CA). A trained group of medical staff performed each of 2 transfer methods: the "manual" and the "Jackson table" transfer. The manual technique entailed performing a standard rotation of the supine patient on a stretcher to the prone position on the operating room table with in-line manual cervical stabilization. The "Jackson" technique involved sliding the supine patient to the Jackson table (OSI, Union City, CA) with manual in-line cervical stabilization, securing them to the table, then initiating the table's lock and turn mechanism and rotating them into a prone position. An electromagnetic tracking device captured angular motion between the C5 and C6 vertebral segments. Repeated measures statistical analysis was performed to evaluate the following conditions: collar use (2 levels), headrest (3 levels), and turning technique (2 levels). For all

  10. Integrating Global Poverty into Mainstream Business Classrooms

    Paton, Bruce; Harris-Boundy, Jason; Melhus, Peter

    2012-01-01

    Most of the products and services discussed in business curricula serve a small portion of humanity. But the great majority of economic growth over the next few decades is expected to occur in emerging and frontier markets. This emerging reality increases the urgency for including topics related to global poverty, unmet human needs, and emergence…

  11. Integrated global digital image correlation for interface delamination characterization

    Hoefnagels, Johan P.M.; Blaysat, Benoî t; Lubineau, Gilles; Geers, Marc G D

    2013-01-01

    , but require accurate interface models to capture (irreversible) crack initiation and propagation behavior observed in experiments. Therefore, an Integrated Global Digital Image Correlation (I-GDIC) strategy is developed for accurate determination of mechanical

  12. Global challenges in integrated coastal zone management

    integration of data and information in policy and management, combining expertise from nature and social science, to reach a balanced and sustainable development of the coastal zone. This important book comprises the proceedings of The International Symposium on Integrated Coastal Zone Management, which took....../mitigation to change in coastal systems Coastal governance Linking science and management Comprising a huge wealth of information, this timely and well-edited volume is essential reading for all those involved in coastal zone management around the globe. All libraries in research establishments and universities where...

  13. two strategies to be integrated into globalization

    Alvarado, Fernando

    2011-01-01

    The present thesis work intends to investigate internal and external factors determining the type of strategy of foreign policy used by Argentina and Chile in order to be part of globalization. In both cases, it is a strategy where the emphasis on the management of foreign policy, more economic than political, prevails. However, under the same external context and similar formal institutional frameworks, the main difference of both strategies may be found in the conceptual approach, which is ...

  14. Integrating Curriculum: A Case Study of Teaching Global Education

    Ferguson-Patrick, Kate; Reynolds, Ruth; Macqueen, Suzanne

    2018-01-01

    Despite widespread support for integrated approaches to teaching, classroom practice reveals a lack of implementation. This paper explores challenges and opportunities in teaching an integrated curriculum, and connects this with the contemporary notion of a twenty-first century curriculum and pedagogy. A case study of Global Education (GE) is used…

  15. Development of an Integrated Global Energy Model

    Krakowski, R.A.

    1999-01-01

    The primary objective of this research was to develop a forefront analysis tool for application to enhance understanding of long-term, global, nuclear-energy and nuclear-material futures. To this end, an existing economics-energy-environmental (E 3 ) model was adopted, modified, and elaborated to examine this problem in a multi-regional (13), long-term (approximately2,100) context. The E 3 model so developed was applied to create a Los Alamos presence in this E 3 area through ''niche analyses'' that provide input to the formulation of policies dealing with and shaping of nuclear-energy and nuclear-materials futures. Results from analyses using the E 3 model have been presented at a variety of national and international conferences and workshops. Through use of the E 3 model Los Alamos was afforded the opportunity to participate in a multi-national E 3 study team that is examining a range of global, long-term nuclear issues under the auspices of the IAEA during the 1998-99 period . Finally, the E 3 model developed under this LDRD project is being used as an important component in more recent Nuclear Material Management Systems (NMMS) project

  16. The Integrative Dimension of the Economic Globalization in European Space

    Daniela Mariana Alexandrache

    2010-06-01

    Full Text Available We believe that globalization and its socio-economic implications of the world and world economic crisis is one of the most debated issues from several years. The publication "The Economist’’ named globalization as the most used word of the century. The most relevant dimension of globalization is the economy with the more dynamic factors: technological development, the hegemony of liberal conceptions (closely linked to the triumph of the ideology of market economy and explosive development of countries or regions. Economic globalization has manifested a series of visible effects such as: the emergence of new markets and foreign trade (interconnected at global level, the appearance of: transnational companies, multilateral agreements on trade, broadening the scope of WTO, transformation of multinational companies in transnational companies and the emergence of global economic markets. Regionally, we noticed that the trendof concentration of economic activity is more pronounced and advanced in the European continent. Expanding globalization in Europe was achieved because of the fall of communism, and the neoliberal reformation which took place in Western European countries. Events like the fall of the Berlin Wall, followed by the fall of communism eradicated many political, economic, religious or cultural barriers. There were born new relations between state and market, public and private. European Union is, in our view, a regional office ofglobalization, representing the best performing integrative system in the world (by creating free trade area, customs union, common market, the Economic and Monetary Union. In terms of the European Commission,European model is a third way towards globalization, a middle path between protectionism and uncontrolled economy. To understand why the EU is an advanced approximation of globalization, perhaps a regional model of globalization, we must first understand the link between globalization and regional

  17. Global integration of European tuna markets

    Jiménez-Toribio, Ramòn; Guillotreau, Patrice; Mongruel, Rémi

    2010-07-01

    This paper evaluates the degree of integration between the world market and the major European marketplaces of frozen and canned tuna through both vertical and horizontal price relationships. Spatial linkages are investigated horizontally in order to estimate the connection between the European market and the world-wide market on the primary stage of the value chain. One of the key results is the high level of market integration at the ex-vessel stage, and the price leadership of yellowfin tuna over skipjack tuna. The same approach is applied at the ex-factory level. Basically, the European market for final goods appears to be segmented between the Northern countries consuming low-priced canned skipjack tuna imported from Asia (mainly Thailand) and the Southern countries (Italy, Spain) processing and importing yellowfin-based products sold at higher prices. France appears to be an intermediate market where both products are consumed. The former market is found to be well integrated to the world market and can be considered to be competitive, but there is a suspicion of market power being exercised on the latter. Price relationships are therefore tested vertically between the price of frozen tuna paid by the canneries and the price of canned fish in both Italy and France. The two species show an opposite pattern in prices transmission along the value chain: price changes along the chain are far better transmitted for the “global” skipjack tuna than for the more “European” yellowfin tuna. The results are discussed, along with their implications for the fishing industry.

  18. Global integration strategies in times of crisis

    Jensen, Camilla

    2017-01-01

    In recent years, we can observe the emergence of firms, born both digital and global, that have disrupted existing industries. Deploying digital technologies, they have developed innovative value chains and business models that threaten established multinational companies (MNCs). In this chapter......, we examine how MNCs can and do respond to the challenge digital technologies represent. We describe the main facets of digital technologies and discus the potential these have to undermine the value chains and business models of established MNCs. In order to illustrate this, we employ longitudinal...... data from Telenor, a leading multinational mobile telecom company. Telenor perceives digitalization as a critical threat that in turn is causing a radical rethink about the viability of its decentralized, locally responsive value chain and business model. Our data provides insights into business models...

  19. Rethinking global health research: towards integrative expertise

    MacLachlan Malcolm

    2009-07-01

    Full Text Available Abstract The Bamako Call for Action on Research for Health stresses the importance of inter-disciplinary, inter-ministerial and inter-sectoral working. This challenges much of our current research and postgraduate research training in health, which mostly seeks to produce narrowly focused content specialists. We now need to compliment this type of research and research training, by offering alternative pathways that seek to create expertise, not only in specific narrow content areas, but also in the process and context of research, as well as in the interaction of these different facets of knowledge. Such an approach, developing 'integrative expertise', could greatly facilitate better research utilisation, helping policy makers and practitioners work through more evidence-based practice and across traditional research boundaries.

  20. RELEVANT PROBLEMS OF UKRAINE’S INTEGRATION INTO GLOBAL ECONOMY

    Yevheniia Duliba

    2017-12-01

    Full Text Available The purpose of this research is to study the main problems that prevent Ukraine from integrating into the global economy and to determine correct focuses of the foreign economic policy of Ukraine against the background of strengthening of globalization tendencies throughout the world. The bases of this research are bases of business development of the foreign economic policy of Ukraine and improvement of Ukrainian economy against the background of international integration. At the heart of the research methodology is a dialectical method of scientific knowledge and, besides, special methods of research based on modern scientific bases of economic, management and related to them knowledge: economic and statistic method – for the assessment of the modern state of foreign trade and investment activity of Ukraine; method of analysis and synthesis – for the determination of tendencies of development of integration processed in Ukraine; comparative analysis – for comparison of information concerning development of specific indicators of foreign economic activities in Ukraine. Results. As a result of research, the main blocks of problems, which impede the integration of Ukraine into the global economy, and requirements for their complex solution are determined. Besides, interdependence and interdetermination of problems, which impede the integration of Ukraine into the global economy, and requirements for their complex solution are explained. Political and legal, economic, sociocultural, and infrastructural preconditions that are necessary for effective integration of Ukraine into the global economy are highlighted. Practical implications. Analysis of the existing problems related to the actual economy, investments, innovation processes gives the possibility to determine the vector of development of Ukraine’s economy taking to account recommendations concerning its improvement for the purposes of integration into global economy. Value

  1. Discrete integrable systems and hodograph transformations arising from motions of discrete plane curves

    Feng Baofeng; Maruno, Ken-ichi; Inoguchi, Jun-ichi; Kajiwara, Kenji; Ohta, Yasuhiro

    2011-01-01

    We consider integrable discretizations of some soliton equations associated with the motions of plane curves: the Wadati-Konno-Ichikawa elastic beam equation, the complex Dym equation and the short pulse equation. They are related to the modified KdV or the sine-Gordon equations by the hodograph transformations. Based on the observation that the hodograph transformations are regarded as the Euler-Lagrange transformations of the curve motions, we construct the discrete analogues of the hodograph transformations, which yield integrable discretizations of those soliton equations. (paper)

  2. Integrals of the motion, Green functions, and coherent states of dynamical systems

    Dodonov, V.V.; Malkin, I.A.; Man'ko, V.I.

    1975-01-01

    The connection between the integrals of the motion of a quantum system and its Green function is established. The Green function is shown to be the eigenfunction of the integrals of the motion which describe initial points of the system trajectory in the phase space of average coordinates and moments. The explicit expressions for the Green functions of the N-dimensional system with the Hamiltonians which is the most general quadratic form of coordinates and momenta with time-dependent coefficients is obtained in coordinate, momentum, and coherent states representations. The Green functions of the nonstationary singular oscillator and of the stationary Schroedinger equation are also obtained. (author)

  3. MRI-assisted PET motion correction for neurologic studies in an integrated MR-PET scanner.

    Catana, Ciprian; Benner, Thomas; van der Kouwe, Andre; Byars, Larry; Hamm, Michael; Chonde, Daniel B; Michel, Christian J; El Fakhri, Georges; Schmand, Matthias; Sorensen, A Gregory

    2011-01-01

    Head motion is difficult to avoid in long PET studies, degrading the image quality and offsetting the benefit of using a high-resolution scanner. As a potential solution in an integrated MR-PET scanner, the simultaneously acquired MRI data can be used for motion tracking. In this work, a novel algorithm for data processing and rigid-body motion correction (MC) for the MRI-compatible BrainPET prototype scanner is described, and proof-of-principle phantom and human studies are presented. To account for motion, the PET prompt and random coincidences and sensitivity data for postnormalization were processed in the line-of-response (LOR) space according to the MRI-derived motion estimates. The processing time on the standard BrainPET workstation is approximately 16 s for each motion estimate. After rebinning in the sinogram space, the motion corrected data were summed, and the PET volume was reconstructed using the attenuation and scatter sinograms in the reference position. The accuracy of the MC algorithm was first tested using a Hoffman phantom. Next, human volunteer studies were performed, and motion estimates were obtained using 2 high-temporal-resolution MRI-based motion-tracking techniques. After accounting for the misalignment between the 2 scanners, perfectly coregistered MRI and PET volumes were reproducibly obtained. The MRI output gates inserted into the PET list-mode allow the temporal correlation of the 2 datasets within 0.2 ms. The Hoffman phantom volume reconstructed by processing the PET data in the LOR space was similar to the one obtained by processing the data using the standard methods and applying the MC in the image space, demonstrating the quantitative accuracy of the procedure. In human volunteer studies, motion estimates were obtained from echo planar imaging and cloverleaf navigator sequences every 3 s and 20 ms, respectively. Motion-deblurred PET images, with excellent delineation of specific brain structures, were obtained using these 2 MRI

  4. Active contour-based visual tracking by integrating colors, shapes, and motions.

    Hu, Weiming; Zhou, Xue; Li, Wei; Luo, Wenhan; Zhang, Xiaoqin; Maybank, Stephen

    2013-05-01

    In this paper, we present a framework for active contour-based visual tracking using level sets. The main components of our framework include contour-based tracking initialization, color-based contour evolution, adaptive shape-based contour evolution for non-periodic motions, dynamic shape-based contour evolution for periodic motions, and the handling of abrupt motions. For the initialization of contour-based tracking, we develop an optical flow-based algorithm for automatically initializing contours at the first frame. For the color-based contour evolution, Markov random field theory is used to measure correlations between values of neighboring pixels for posterior probability estimation. For adaptive shape-based contour evolution, the global shape information and the local color information are combined to hierarchically evolve the contour, and a flexible shape updating model is constructed. For the dynamic shape-based contour evolution, a shape mode transition matrix is learnt to characterize the temporal correlations of object shapes. For the handling of abrupt motions, particle swarm optimization is adopted to capture the global motion which is applied to the contour in the current frame to produce an initial contour in the next frame.

  5. Integrating scientific, economic, and ecological aspects of global change

    Jacoby, H.D.; Yang, Z.

    1994-01-01

    The MIT Joint Program on the Science and Policy of Global Change is conducting research on methods for integrating the science of potential global change with economic analysis of litigation policies and quantification of economic and environmental impacts. The paper describes this work, with a focus on the way that research within the various contributing disciplines, and the design of their associated models, are influenced by the process of inclusion in an integrated framework for policy analysis. The results should contribute new insight into the relative importance of key feedbacks within the economy-climate-ecology system

  6. Integration of visual and inertial cues in perceived heading of self-motion

    Winkel, K.N. de; Weesie, H.M.; Werkhoven, P.J.; Groen, E.L.

    2010-01-01

    In the present study, we investigated whether the perception of heading of linear self-motion can be explained by Maximum Likelihood Integration (MLI) of visual and non-visual sensory cues. MLI predicts smaller variance for multisensory judgments compared to unisensory judgments. Nine participants

  7. Integration of visual and inertial cues in the perception of angular self-motion

    Winkel, K.N. de; Soyka, F.; Barnett-Cowan, M.; Bülthoff, H.H.; Groen, E.L.; Werkhoven, P.J.

    2013-01-01

    The brain is able to determine angular self-motion from visual, vestibular, and kinesthetic information. There is compelling evidence that both humans and non-human primates integrate visual and inertial (i.e., vestibular and kinesthetic) information in a statistically optimal fashion when

  8. On the integration of equations of motion for particle-in-cell codes

    Fuchs, Vladimír; Gunn, J. P.

    2006-01-01

    Roč. 214, - (2006), s. 299-315 ISSN 0021-9991 R&D Projects: GA ČR GA202/04/0360 Institutional research plan: CEZ:AV0Z20430508 Keywords : Equations of motion * 2nd order integration methods * nonlinear oscillations Subject RIV: BM - Solid Matter Physics ; Magnetism Impact factor: 2.328, year: 2006

  9. A canonical process for estimation of convex functions : The "invelope" of integrated Brownian motion +t4

    Groeneboom, P.; Jongbloed, G.; Wellner, J.A.

    2001-01-01

    A process associated with integrated Brownian motion is introduced that characterizes the limit behavior of nonparametric least squares and maximum likelihood estimators of convex functions and convex densities, respectively. We call this process “the invelope” and show that it is an almost surely

  10. An integrated artificial neural networks approach for predicting global radiation

    Azadeh, A.; Maghsoudi, A.; Sohrabkhani, S.

    2009-01-01

    This article presents an integrated artificial neural network (ANN) approach for predicting solar global radiation by climatological variables. The integrated ANN trains and tests data with multi layer perceptron (MLP) approach which has the lowest mean absolute percentage error (MAPE). The proposed approach is particularly useful for locations where no available measurement equipment. Also, it considers all related climatological and meteorological parameters as input variables. To show the applicability and superiority of the integrated ANN approach, monthly data were collected for 6 years (1995-2000) in six nominal cities in Iran. Separate model for each city is considered and the quantity of solar global radiation in each city is calculated. Furthermore an integrated ANN model has been introduced for prediction of solar global radiation. The acquired results of the integrated model have shown high accuracy of about 94%. The results of the integrated model have been compared with traditional angstrom's model to show its considerable accuracy. Therefore, the proposed approach can be used as an efficient tool for prediction of solar radiation in the remote and rural locations with no direct measurement equipment.

  11. A wearable 3D motion sensing system integrated with a Bluetooth smart phone application: A system level overview

    Karimi, Muhammad Akram; Shamim, Atif

    2018-01-01

    description of a wearable 3D motion sensor. The sensing mechanism is based upon well-established magnetic and inertial measurement unit (MIMU), which integrates accelerometer, gyroscope and magnetometer data. Two sensor boards have been integrated within a

  12. Integration of Visual and Vestibular Information Used to Discriminate Rotational Self-Motion

    Florian Soyka

    2011-10-01

    Full Text Available Do humans integrate visual and vestibular information in a statistically optimal fashion when discriminating rotational self-motion stimuli? Recent studies are inconclusive as to whether such integration occurs when discriminating heading direction. In the present study eight participants were consecutively rotated twice (2s sinusoidal acceleration on a chair about an earth-vertical axis in vestibular-only, visual-only and visual-vestibular trials. The visual stimulus was a video of a moving stripe pattern, synchronized with the inertial motion. Peak acceleration of the reference stimulus was varied and participants reported which rotation was perceived as faster. Just-noticeable differences (JND were estimated by fitting psychometric functions. The visual-vestibular JND measurements are too high compared to the predictions based on the unimodal JND estimates and there is no JND reduction between visual-vestibular and visual-alone estimates. These findings may be explained by visual capture. Alternatively, the visual precision may not be equal between visual-vestibular and visual-alone conditions, since it has been shown that visual motion sensitivity is reduced during inertial self-motion. Therefore, measuring visual-alone JNDs with an underlying uncorrelated inertial motion might yield higher visual-alone JNDs compared to the stationary measurement. Theoretical calculations show that higher visual-alone JNDs would result in predictions consistent with the JND measurements for the visual-vestibular condition.

  13. A global earthquake discrimination scheme to optimize ground-motion prediction equation selection

    Garcia, Daniel; Wald, David J.; Hearne, Michael

    2012-01-01

    We present a new automatic earthquake discrimination procedure to determine in near-real time the tectonic regime and seismotectonic domain of an earthquake, its most likely source type, and the corresponding ground-motion prediction equation (GMPE) class to be used in the U.S. Geological Survey (USGS) Global ShakeMap system. This method makes use of the Flinn–Engdahl regionalization scheme, seismotectonic information (plate boundaries, global geology, seismicity catalogs, and regional and local studies), and the source parameters available from the USGS National Earthquake Information Center in the minutes following an earthquake to give the best estimation of the setting and mechanism of the event. Depending on the tectonic setting, additional criteria based on hypocentral depth, style of faulting, and regional seismicity may be applied. For subduction zones, these criteria include the use of focal mechanism information and detailed interface models to discriminate among outer-rise, upper-plate, interface, and intraslab seismicity. The scheme is validated against a large database of recent historical earthquakes. Though developed to assess GMPE selection in Global ShakeMap operations, we anticipate a variety of uses for this strategy, from real-time processing systems to any analysis involving tectonic classification of sources from seismic catalogs.

  14. Simulation analysis of globally integrated logistics and recycling strategies

    Song, S.J.; Hiroshi, K. [Hiroshima Inst. of Tech., Graduate School of Mechanical Systems Engineering, Dept. of In formation and Intelligent Systems Engineering, Hiroshima (Japan)

    2004-07-01

    This paper focuses on the optimal analysis of world-wide recycling activities associated with managing the logistics and production activities in global manufacturing whose activities stretch across national boundaries. Globally integrated logistics and recycling strategies consist of the home country and two free trading economic blocs, NAFTA and ASEAN, where significant differences are found in production and disassembly cost, tax rates, local content rules and regulations. Moreover an optimal analysis of globally integrated value-chain was developed by applying simulation optimization technique as a decision-making tool. The simulation model was developed and analyzed by using ProModel packages, and the results help to identify some of the appropriate conditions required to make well-performed logistics and recycling plans in world-wide collaborated manufacturing environment. (orig.)

  15. Integration of MATLAB Simulink(Registered Trademark) Models with the Vertical Motion Simulator

    Lewis, Emily K.; Vuong, Nghia D.

    2012-01-01

    This paper describes the integration of MATLAB Simulink(Registered TradeMark) models into the Vertical Motion Simulator (VMS) at NASA Ames Research Center. The VMS is a high-fidelity, large motion flight simulator that is capable of simulating a variety of aerospace vehicles. Integrating MATLAB Simulink models into the VMS needed to retain the development flexibility of the MATLAB environment and allow rapid deployment of model changes. The process developed at the VMS was used successfully in a number of recent simulation experiments. This accomplishment demonstrated that the model integrity was preserved, while working within the hard real-time run environment of the VMS architecture, and maintaining the unique flexibility of the VMS to meet diverse research requirements.

  16. MR-assisted PET Motion Correction for eurological Studies in an Integrated MR-PET Scanner

    Catana, Ciprian; Benner, Thomas; van der Kouwe, Andre; Byars, Larry; Hamm, Michael; Chonde, Daniel B.; Michel, Christian J.; El Fakhri, Georges; Schmand, Matthias; Sorensen, A. Gregory

    2011-01-01

    Head motion is difficult to avoid in long PET studies, degrading the image quality and offsetting the benefit of using a high-resolution scanner. As a potential solution in an integrated MR-PET scanner, the simultaneously acquired MR data can be used for motion tracking. In this work, a novel data processing and rigid-body motion correction (MC) algorithm for the MR-compatible BrainPET prototype scanner is described and proof-of-principle phantom and human studies are presented. Methods To account for motion, the PET prompts and randoms coincidences as well as the sensitivity data are processed in the line or response (LOR) space according to the MR-derived motion estimates. After sinogram space rebinning, the corrected data are summed and the motion corrected PET volume is reconstructed from these sinograms and the attenuation and scatter sinograms in the reference position. The accuracy of the MC algorithm was first tested using a Hoffman phantom. Next, human volunteer studies were performed and motion estimates were obtained using two high temporal resolution MR-based motion tracking techniques. Results After accounting for the physical mismatch between the two scanners, perfectly co-registered MR and PET volumes are reproducibly obtained. The MR output gates inserted in to the PET list-mode allow the temporal correlation of the two data sets within 0.2 s. The Hoffman phantom volume reconstructed processing the PET data in the LOR space was similar to the one obtained processing the data using the standard methods and applying the MC in the image space, demonstrating the quantitative accuracy of the novel MC algorithm. In human volunteer studies, motion estimates were obtained from echo planar imaging and cloverleaf navigator sequences every 3 seconds and 20 ms, respectively. Substantially improved PET images with excellent delineation of specific brain structures were obtained after applying the MC using these MR-based estimates. Conclusion A novel MR-based MC

  17. Systems Approaches: A Global and Historical Perspective on Integrative Medicine

    2012-01-01

    The globalization of healing systems is a dance of cultural awareness and cultural dominance that has arisen throughout history. With the development of greater communication and interest in whole-systems approaches to healing, the opportunity for the development of a global perspective on healing has emerged with new life force. The birth of integrative holistic healing systems in the West, such as naturopathic, homeopathic, anthroposophic, integral and functional medicine, and others, echoes the ocean of wisdom present in traditional healing systems, such as traditional Chinese medicine (TCM) and Ayurveda. In working to integrate the lessons from these systems, we see the inextricable link between man and the natural world, we work to understand the root cause of disease, we focus on the whole person to return balance, and we use empiric observation in large populations over time to grasp the interrelationships inherent in the whole-systems view of illness and wellness. PMID:24278794

  18. Global symplectic structure-preserving integrators for spinning compact binaries

    Zhong, Shuang-Ying; Wu, Xin; Liu, San-Qiu; Deng, Xin-Fa

    2010-12-01

    This paper deals mainly with the application of the second-order symplectic implicit midpoint rule and its symmetric compositions to a post-Newtonian Hamiltonian formulation with canonical spin variables in relativistic compact binaries. The midpoint rule, as a basic algorithm, is directly used to integrate the completely canonical Hamiltonian system. On the other hand, there are symmetric composite methods based on a splitting of the Hamiltonian into two parts: the Newtonian part associated with a Kepler motion, and a perturbation part involving the orbital post-Newtonian and spin contributions, where the Kepler flow has an analytic solution and the perturbation can be calculated by the midpoint rule. An example is the second-order mixed leapfrog symplectic integrator with one stage integration of the perturbation flow and two semistage computations of the Kepler flow at every integration step. Also, higher-order composite methods such as the Forest-Ruth fourth-order symplectic integrator and its optimized algorithm are applicable. Various numerical tests including simulations of chaotic orbits show that the mixed leapfrog integrator is always superior to the midpoint rule in energy accuracy, while both of them are almost equivalent in computational efficiency. Particularly, the optimized fourth-order algorithm compared with the mixed leapfrog scheme provides good precision and needs no expensive additional computational time. As a result, it is worth performing a more detailed and careful examination of the dynamical structure of chaos and order in the parameter windows and phase space of the binary system.

  19. The global signature of post-1900 land ice wastage on vertical land motion

    Riva, Riccardo; Frederikse, Thomas; King, Matt; Marzeion, Ben; van den Broeke, Michiel

    2017-04-01

    The amount of ice stored on land has strongly declined during the 20th century, and melt rates showed a significant acceleration over the last two decades. Land ice wastage is well known to be one of the main drivers of global mean sea-level rise, as widely discussed in the literature and reflected in the last assessment report of the IPCC. A less obvious effect of melting land ice is the response of the solid earth to mass redistribution on its surface, which, in the first approximation, results in land uplift where the load reduces (e.g., close to the meltwater sources) and land subsidence where the load increases (e.g., under the rising oceans). This effect is nowadays well known within the cryospheric and sea level communities. However, what is often not realized is that the solid earth response is a truly global effect: a localized mass change does cause a large deformation signal in its proximity, but also causes a change of the position of every other point on the Earth's surface. The theory of the Earth's elastic response to changing surface loads forms the basis of the 'sea-level equation', which allows sea-level fingerprints of continental mass change to be computed. In this paper, we provide the first dedicated analysis of global vertical land motion driven by land ice wastage. By means of established techniques to compute the solid earth elastic response to surface load changes and the most recent datasets of glacier and ice sheet mass change, we show that land ice loss currently leads to vertical deformation rates of several tenths of mm per year at mid-latitudes, especially over the Northern Hemisphere where most sources are located. In combination with the improved accuracy of space geodetic techniques (e.g., Global Navigation Satellite Systems), this means that the effect of ice melt is non-negligible over a large part of the continents. In particular, we show how deformation rates have been strongly varying through the last century, which implies

  20. High-accuracy numerical integration of charged particle motion – with application to ponderomotive force

    Furukawa, Masaru; Ohkawa, Yushiro; Matsuyama, Akinobu

    2016-01-01

    A high-accuracy numerical integration algorithm for a charged particle motion is developed. The algorithm is based on the Hamiltonian mechanics and the operator decomposition. The algorithm is made to be time-reversal symmetric, and its order of accuracy can be increased to any order by using a recurrence formula. One of the advantages is that it is an explicit method. An effective way to decompose the time evolution operator is examined; the Poisson tensor is decomposed and non-canonical variables are adopted. The algorithm is extended to a time dependent fields' case by introducing the extended phase space. Numerical tests showing the performance of the algorithm are presented. One is the pure cyclotron motion for a long time period, and the other is a charged particle motion in a rapidly oscillating field. (author)

  1. Coordination and Integration of Global Ocean Observing through JCOMM

    Legler, D. M.; Meldrum, D. T.; Hill, K. L.; Charpentier, E.

    2016-02-01

    The primary objective of the JCOMM Observations Coordination Group (OCG) is to provide technical coordination to implement fully integrated ocean observing system across the entire marine meteorology and oceanographic community. JCOMM OCG works in partnership with the Global Ocean Observing System, , which focusses on setting observing system requirements and conducting evalutions. JCOMM OCG initially focused on major global observing networks (e.g. Argo profiling floats, moored buoys, ship based observations, sea level stations, reference sites, etc), and is now expanding its horizon in recognition of new observing needs and new technologies/networks (e.g. ocean gliders). Over the next five years the JCOMM OCG is focusing its attention on integration and coordination in four major areas: observing network implementation particularly in response to integrated ocean observing requirements; observing system monitoring and metrics; standards and best practices; and improving integrated data management and access. This presentation will describe the scope and mission of JCOMM OCG; summarize the state of the global ocean observing system; highlight recent successes and resources for the research, prediction, and assessment communities; summarize our plans for the next several years; and suggest engagement opportunities.

  2. On the integration of equations of motion for particle-in-cell codes

    Fuchs, V.; Gunn, J.P.

    2006-01-01

    An area-preserving implementation of the 2nd order Runge-Kutta integration method for equations of motion is presented. For forces independent of velocity the scheme possesses the same numerical simplicity and stability as the leapfrog method, and is not implicit for forces which do depend on velocity. It can be therefore easily applied where the leapfrog method in general cannot. We discuss the stability of the new scheme and test its performance in calculations of particle motion in three cases of interest. First, in the ubiquitous and numerically demanding example of nonlinear interaction of particles with a propagating plane wave, second, in the case of particle motion in a static magnetic field and, third, in a nonlinear dissipative case leading to a limit cycle. We compare computed orbits with exact orbits and with results from the leapfrog and other low-order integration schemes. Of special interest is the role of intrinsic stochasticity introduced by time differencing, which can destroy orbits of an otherwise exactly integrable system and therefore constitutes a restriction on the applicability of an integration scheme in such a context [A. Friedman, S.P. Auerbach, J. Comput. Phys. 93 (1991) 171]. In particular, we show that for a plane wave the new scheme proposed herein can be reduced to a symmetric standard map. This leads to the nonlinear stability condition Δt ω B ≤ 1, where Δt is the time step and ω B the particle bounce frequency

  3. Collaboration in Global Software Engineering Based on Process Description Integration

    Klein, Harald; Rausch, Andreas; Fischer, Edward

    Globalization is one of the big trends in software development. Development projects need a variety of different resources with appropriate expert knowledge to be successful. More and more of these resources are nowadays obtained from specialized organizations and countries all over the world, varying in development approaches, processes, and culture. As seen with early outsourcing attempts, collaboration may fail due to these differences. Hence, the major challenge in global software engineering is to streamline collaborating organizations towards a successful conjoint development. Based on typical collaboration scenarios, this paper presents a structured approach to integrate processes in a comprehensible way.

  4. Global asymptotic stability of density dependent integral population projection models.

    Rebarber, Richard; Tenhumberg, Brigitte; Townley, Stuart

    2012-02-01

    Many stage-structured density dependent populations with a continuum of stages can be naturally modeled using nonlinear integral projection models. In this paper, we study a trichotomy of global stability result for a class of density dependent systems which include a Platte thistle model. Specifically, we identify those systems parameters for which zero is globally asymptotically stable, parameters for which there is a positive asymptotically stable equilibrium, and parameters for which there is no asymptotically stable equilibrium. Copyright © 2011 Elsevier Inc. All rights reserved.

  5. Integration of motion energy from overlapping random background noise increases perceived speed of coherently moving stimuli.

    Chuang, Jason; Ausloos, Emily C; Schwebach, Courtney A; Huang, Xin

    2016-12-01

    The perception of visual motion can be profoundly influenced by visual context. To gain insight into how the visual system represents motion speed, we investigated how a background stimulus that did not move in a net direction influenced the perceived speed of a center stimulus. Visual stimuli were two overlapping random-dot patterns. The center stimulus moved coherently in a fixed direction, whereas the background stimulus moved randomly. We found that human subjects perceived the speed of the center stimulus to be significantly faster than its veridical speed when the background contained motion noise. Interestingly, the perceived speed was tuned to the noise level of the background. When the speed of the center stimulus was low, the highest perceived speed was reached when the background had a low level of motion noise. As the center speed increased, the peak perceived speed was reached at a progressively higher background noise level. The effect of speed overestimation required the center stimulus to overlap with the background. Increasing the background size within a certain range enhanced the effect, suggesting spatial integration. The speed overestimation was significantly reduced or abolished when the center stimulus and the background stimulus had different colors, or when they were placed at different depths. When the center- and background-stimuli were perceptually separable, speed overestimation was correlated with perceptual similarity between the center- and background-stimuli. These results suggest that integration of motion energy from random motion noise has a significant impact on speed perception. Our findings put new constraints on models regarding the neural basis of speed perception. Copyright © 2016 the American Physiological Society.

  6. Energy integration: Regional economic integration lever and possible insertion factor in the global economy

    Lokolo, M.C.

    2001-01-01

    In the 1920s, just after the War, an idea began taking root in the Old Continent, to build what could be described as the United States of Europe. Thirty years later, in 1951, a new source of energy, coal, paved the way for the economic integration of Europe. It culminated into monetary integration in January 2002. Economic integration makes sense in the context of the relatively small size of some national economies and markets, and the judicious utilization of rare resources and their unequal distribution. In this document, the author elaborated on the principles at play in economic integration and argued that the integration of the national energy markets could be the lever for economic integration through the gradual elimination of the various obstacles to trade. The author first presented a brief historical overview of economic integration from the perspective of global economic relationships, covering the period between the two world wars to the General Agreement on Tariffs and Trade (GATT) to the World Trade Organization (WTO). The concept and the forms of economic integration were reviewed. Energy integration as a lever of regional economic integration and as a factor in global economic insertion were discussed. Energy integration is a tool for the improvement of the human condition. 15 refs

  7. PARALLEL INTEGRATION ALGORITHM AND ITS USAGE FOR A PRACTICAL SIMULATION OF SPACECRAFT ATTITUDE MOTION

    Ravil’ Kudermetov

    2018-02-01

    Full Text Available Nowadays multi-core processors are installed almost in each modern workstation, but the question of these computational resources effective utilization is still a topical one. In this paper the four-point block one-step integration method is considered, the parallel algorithm of this method is proposed and the Java programmatic implementation of this algorithm is discussed. The effectiveness of the proposed algorithm is demonstrated by way of spacecraft attitude motion simulation. The results of this work can be used for practical simulation of dynamic systems that are described by ordinary differential equations. The results are also applicable to the development and debugging of computer programs that integrate the dynamic and kinematic equations of the angular motion of a rigid body.

  8. Dimensionality and integrals of motion of the Trappist-1 planetary system

    Floß, Johannes; Rein, Hanno; Brumer, Paul

    2018-04-01

    The number of isolating integrals of motion of the Trappist-1 system - a late M-dwarf orbited by seven Earth-sized planets - was determined numerically, using an adapted version of the correlation dimension method. It was found that over the investigated time-scales of up to 20 000 years the number of isolating integrals of motion is the same as one would find for a system of seven non-interacting planets - despite the fact that the planets in the Trappist-1 system are strongly interacting. Considering perturbed versions of the Trappist-1 system shows that the system may occupy an atypical part of phase-space with high stability. These findings are consistent with earlier studies.

  9. Implementation of U.S. Global Goals: Continental Integration Context

    Yaroslava Stolyarchuk

    2013-02-01

    Full Text Available The article provides efficiency assessment regarding existing mechanisms of the U.S. national interests’ implementation at the global level in terms of international competition aggravation and formation of the new global economic competition centers. Based on comparative analysis of the leverage for U.S. leadership in global competition it has been proven that currently the highest efficiency is demonstrated by the integration strategies of the USA in Latin America focused on maximizing implementation of the economic interests of U.S. transnational corporations in the region. It has been proven that the observed profound asymmetries regarding socio-economic development of the North and Latin America countries objectively requires implementation of the effective institutional mechanisms for leveling the negative effects generated by the trade and investment liberalization processes.

  10. Integrating developing country manufacturing industries into global supply chain

    Fasika Bete Georgise

    2014-01-01

    Full Text Available Purpose: Due to globalization of manufacturing activities, the arena of competition and competitiveness advantage is moving from firms towards supply chains and networks. With the recent advancement of information and communication technologies this participation are becoming as common business practice in developed countries firms. Companies were more integrated into the world market for the global nature of the sourcing, manufacturing and distribution. These changes create both challenges and opportunities for the manufacturing industries in developing countries. The objective of this paper is to examine the level of inter-organizational and intra-organizational supply chain integration practices in developing country, Ethiopia.Design/methodology/approach: An industrial questionnaires survey was used to collect the current practices of the manufacturing industries in Ethiopia as an example of the developing countries. Descriptive statistics is primarily used for the analysis.Findings: Results show a low level of supply chain relationship both in intra and inter organizational supply chain integration level among members. Accordingly, such issues require much attention to facilitate a greater integration within the supply chains in the Ethiopian manufacturing industries.Research limitations/implications: The paper focuses on examining the practices of Ethiopian manufacturing industries empirical data. The interpretation of results should be taken with prudence.Originality/Value: The manufacturing industry in developing countries (MIDC has been a part of the global supply chains for long time as a supplier of raw material and manufacturer of primary products. Currently, the MIDC is trying to access the different markets segment of the world even with new products starting from their local market to the complex and dynamic international market. Nevertheless, their supply chains are inefficient and hence, their competitiveness level far from the

  11. A 4D global respiratory motion model of the thorax based on CT images: A proof of concept.

    Fayad, Hadi; Gilles, Marlene; Pan, Tinsu; Visvikis, Dimitris

    2018-05-17

    Respiratory motion reduces the sensitivity and specificity of medical images especially in the thoracic and abdominal areas. It may affect applications such as cancer diagnostic imaging and/or radiation therapy (RT). Solutions to this issue include modeling of the respiratory motion in order to optimize both diagnostic and therapeutic protocols. Personalized motion modeling required patient-specific four-dimensional (4D) imaging which in the case of 4D computed tomography (4D CT) acquisition is associated with an increased dose. The goal of this work was to develop a global respiratory motion model capable of relating external patient surface motion to internal structure motion without the need for a patient-specific 4D CT acquisition. The proposed global model is based on principal component analysis and can be adjusted to a given patient anatomy using only one or two static CT images in conjunction with a respiratory synchronized patient external surface motion. It is based on the relation between the internal motion described using deformation fields obtained by registering 4D CT images and patient surface maps obtained either from optical imaging devices or extracted from CT image-based patient skin segmentation. 4D CT images of six patients were used to generate the global motion model which was validated by adapting it on four different patients having skin segmented surfaces and two other patients having time of flight camera acquired surfaces. The reproducibility of the proposed model was also assessed on two patients with two 4D CT series acquired within 2 weeks of each other. Profile comparison shows the efficacy of the global respiratory motion model and an improvement while using two CT images in order to adapt the model. This was confirmed by the correlation coefficient with a mean correlation of 0.9 and 0.95 while using one or two CT images respectively and when comparing acquired to model generated 4D CT images. For the four patients with segmented

  12. The Effects of Applying Game-Based Learning to Webcam Motion Sensor Games for Autistic Students' Sensory Integration Training

    Li, Kun-Hsien; Lou, Shi-Jer; Tsai, Huei-Yin; Shih, Ru-Chu

    2012-01-01

    This study aims to explore the effects of applying game-based learning to webcam motion sensor games for autistic students' sensory integration training for autistic students. The research participants were three autistic students aged from six to ten. Webcam camera as the research tool wad connected internet games to engage in motion sensor…

  13. 76 FR 5834 - International Business Machines Corporation, Global Technology Services Business Unit, Integrated...

    2011-02-02

    ... Machines Corporation, Global Technology Services Business Unit, Integrated Technology Services, Cost and..., applicable to workers of International Business Machines Corporation, Global Technology Services Business... engaged in activities related to support for the Global Technology Services Business Unit. The company...

  14. Integration Head Mounted Display Device and Hand Motion Gesture Device for Virtual Reality Laboratory

    Rengganis, Y. A.; Safrodin, M.; Sukaridhoto, S.

    2018-01-01

    Virtual Reality Laboratory (VR Lab) is an innovation for conventional learning media which show us whole learning process in laboratory. There are many tools and materials are needed by user for doing practical in it, so user could feel new learning atmosphere by using this innovation. Nowadays, technologies more sophisticated than before. So it would carry in education and it will be more effective, efficient. The Supported technologies are needed us for making VR Lab such as head mounted display device and hand motion gesture device. The integration among them will be used us for making this research. Head mounted display device for viewing 3D environment of virtual reality laboratory. Hand motion gesture device for catching user real hand and it will be visualized in virtual reality laboratory. Virtual Reality will show us, if using the newest technologies in learning process it could make more interesting and easy to understand.

  15. INTEGRATED MECHANISMS FOR APROACHING PRIORITY ENVIRONMENTAL ISSUES AT GLOBAL LEVEL

    iLDIKO iOAN

    2011-03-01

    Full Text Available Integrated mechanisms for approaching priority environmentalissues at global level. At global level, there are considered priorityenvironmental issues two interdependent processes that are essential for thesupport the processes that provide living conditions and wellbeing for the entirehumankind: climate change and loss of biodiversity. Payments of ecosystemservices became already well-known and applied economic instruments, althoughthere are still many uncertainties in the knowledge of eco-economic interdependencies.The paper discusses these aspects in the first part highlighting advantagesand disadvantages, while in the second part there is analyzed an integratedprogram of the United Nations, which was designed for making progress towardboth climate change, and loss of biodiversity. The REDD program – Reduction ofEmissions from Deforestation and forest Degradation – is addressed to developingcountries and it started in 2008. Based on assessment reports we will try toformulate a number of conclusions regarding the program’s effectiveness.

  16. Dynamics on strata of trigonal Jacobians and some integrable problems of rigid body motion

    Braden, H W; Enolski, V Z; Fedorov, Yu N

    2013-01-01

    We present an algebraic geometrical and analytical description of the Goryachev case of rigid body motion. It belongs to a family of systems sharing the same properties: although completely integrable, they are not algebraically integrable, their solution is not meromorphic in the complex time and involves dynamics on the strata of the Jacobian varieties of trigonal curves. Although the strata of hyperelliptic Jacobians have already appeared in the literature in the context of some dynamical systems, the Goryachev case is the first example of an integrable system whose solution involves a more general curve. Several new features (and formulae) are encountered in the solution given in terms of sigma-functions of such a curve. (paper)

  17. Dynamic PET image reconstruction integrating temporal regularization associated with respiratory motion correction for applications in oncology

    Merlin, Thibaut; Visvikis, Dimitris; Fernandez, Philippe; Lamare, Frédéric

    2018-02-01

    Respiratory motion reduces both the qualitative and quantitative accuracy of PET images in oncology. This impact is more significant for quantitative applications based on kinetic modeling, where dynamic acquisitions are associated with limited statistics due to the necessity of enhanced temporal resolution. The aim of this study is to address these drawbacks, by combining a respiratory motion correction approach with temporal regularization in a unique reconstruction algorithm for dynamic PET imaging. Elastic transformation parameters for the motion correction are estimated from the non-attenuation-corrected PET images. The derived displacement matrices are subsequently used in a list-mode based OSEM reconstruction algorithm integrating a temporal regularization between the 3D dynamic PET frames, based on temporal basis functions. These functions are simultaneously estimated at each iteration, along with their relative coefficients for each image voxel. Quantitative evaluation has been performed using dynamic FDG PET/CT acquisitions of lung cancer patients acquired on a GE DRX system. The performance of the proposed method is compared with that of a standard multi-frame OSEM reconstruction algorithm. The proposed method achieved substantial improvements in terms of noise reduction while accounting for loss of contrast due to respiratory motion. Results on simulated data showed that the proposed 4D algorithms led to bias reduction values up to 40% in both tumor and blood regions for similar standard deviation levels, in comparison with a standard 3D reconstruction. Patlak parameter estimations on reconstructed images with the proposed reconstruction methods resulted in 30% and 40% bias reduction in the tumor and lung region respectively for the Patlak slope, and a 30% bias reduction for the intercept in the tumor region (a similar Patlak intercept was achieved in the lung area). Incorporation of the respiratory motion correction using an elastic model along with a

  18. Integration of auditory and kinesthetic information in motion: alterations in Parkinson's disease.

    Sabaté, Magdalena; Llanos, Catalina; Rodríguez, Manuel

    2008-07-01

    The main aim in this work was to study the interaction between auditory and kinesthetic stimuli and its influence on motion control. The study was performed on healthy subjects and patients with Parkinson's disease (PD). Thirty-five right-handed volunteers (young, PD, and age-matched healthy participants, and PD-patients) were studied with three different motor tasks (slow cyclic movements, fast cyclic movements, and slow continuous movements) and under the action of kinesthetic stimuli and sounds at different beat rates. The action of kinesthesia was evaluated by comparing real movements with virtual movements (movements imaged but not executed). The fast cyclic task was accelerated by kinesthetic but not by auditory stimuli. The slow cyclic task changed with the beat rate of sounds but not with kinesthetic stimuli. The slow continuous task showed an integrated response to both sensorial modalities. These data show that the influence of the multisensory integration on motion changes with the motor task and that some motor patterns are modulated by the simultaneous action of auditory and kinesthetic information, a cross-modal integration that was different in PD-patients. PsycINFO Database Record (c) 2008 APA, all rights reserved.

  19. A wearable 3D motion sensing system integrated with a Bluetooth smart phone application: A system level overview

    Karimi, Muhammad Akram

    2018-01-02

    An era of ubiquitous motion sensing has just begun. All electronic gadgets ranging from game consoles to mobile phones have some sort of motion sensors in them. In contrast to rigid motion sensing systems, this paper presents a system level description of a wearable 3D motion sensor. The sensing mechanism is based upon well-established magnetic and inertial measurement unit (MIMU), which integrates accelerometer, gyroscope and magnetometer data. Two sensor boards have been integrated within a wearable arm sleeve to capture 3D orientation of the human arm. The sensors have been interfaced with a Bluetooth transceiver chip, which transmits data to a mobile phone app using standard Bluetooth protocol. An android mobile phone app has been developed to display the human arm motion in real time.

  20. Many-body-localization: strong disorder perturbative approach for the local integrals of motion

    Monthus, Cécile

    2018-05-01

    For random quantum spin models, the strong disorder perturbative expansion of the local integrals of motion around the real-spin operators is revisited. The emphasis is on the links with other properties of the many-body-localized phase, in particular the memory in the dynamics of the local magnetizations and the statistics of matrix elements of local operators in the eigenstate basis. Finally, this approach is applied to analyze the many-body-localization transition in a toy model studied previously from the point of view of the entanglement entropy.

  1. Integrated global digital image correlation for interface delamination characterization

    Hoefnagels, Johan P.M.

    2013-07-23

    Interfacial delamination is a key reliability challenge in composites and micro-electronic systems due to (high-density) integration of dissimilar materials. Predictive finite element models are used to minimize delamination failures during design, but require accurate interface models to capture (irreversible) crack initiation and propagation behavior observed in experiments. Therefore, an Integrated Global Digital Image Correlation (I-GDIC) strategy is developed for accurate determination of mechanical interface behavior from in-situ delamination experiments. Recently, a novel miniature delamination setup was presented that enables in-situ microscopic characterization of interface delamination while sensitively measuring global load-displacement curves for all mode mixities. Nevertheless, extraction of detailed mechanical interface behavior from measured images is challenging, because deformations are tiny and measurement noise large. Therefore, an advanced I-GDIC methodology is developed which correlates the image patterns by only deforming the images using kinematically-admissible \\'eigenmodes\\' that correspond to the few parameters controlling the interface tractions in an analytic description of the crack tip deformation field, thereby greatly enhancing accuracy and robustness. This method is validated on virtual delamination experiments, simulated using a recently developed self-adaptive cohesive zone (CZ) finite element framework. © The Society for Experimental Mechanics, Inc. 2014.

  2. Improved data for integrated modeling of global environmental change

    Lotze-Campen, Hermann

    2011-12-01

    The assessment of global environmental changes, their impact on human societies, and possible management options requires large-scale, integrated modeling efforts. These models have to link biophysical with socio-economic processes, and they have to take spatial heterogeneity of environmental conditions into account. Land use change and freshwater use are two key research areas where spatial aggregation and the use of regional average numbers may lead to biased results. Useful insights can only be obtained if processes like economic globalization can be consistently linked to local environmental conditions and resource constraints (Lambin and Meyfroidt 2011). Spatially explicit modeling of environmental changes at the global scale has a long tradition in the natural sciences (Woodward et al 1995, Alcamo et al 1996, Leemans et al 1996). Socio-economic models with comparable spatial detail, e.g. on grid-based land use change, are much less common (Heistermann et al 2006), but are increasingly being developed (Popp et al 2011, Schneider et al 2011). Spatially explicit models require spatially explicit input data, which often constrains their development and application at the global scale. The amount and quality of available data on environmental conditions is growing fast—primarily due to improved earth observation methods. Moreover, systematic efforts for collecting and linking these data across sectors are on the way (www.earthobservations.org). This has, among others, also helped to provide consistent databases on different land cover and land use types (Erb et al 2007). However, spatially explicit data on specific anthropogenic driving forces of global environmental change are still scarce—also because these cannot be collected with satellites or other devices. The basic data on socio-economic driving forces, i.e. population density and wealth (measured as gross domestic product per capita), have been prepared for spatially explicit analyses (CIESIN, IFPRI

  3. Modular injector integrated linear apparatus with motion profile optimization for spatial atomic layer deposition

    Wang, Xiaolei; Li, Yun; Lin, Jilong; Shan, Bin; Chen, Rong

    2017-11-01

    A spatial atomic layer deposition apparatus integrated with a modular injector and a linear motor has been designed. It consists of four parts: a precursor delivery manifold, a modular injector, a reaction zone, and a driving unit. An injector with multi-layer structured channels is designed to help improve precursor distribution homogeneity. During the back and forth movement of the substrate at high speed, the inertial impact caused by jerk and sudden changes of acceleration will degrade the film deposition quality. Such residual vibration caused by inertial impact will aggravate the fluctuation of the gap distance between the injector and the substrate in the deposition process. Thus, an S-curve motion profile is implemented to reduce the large inertial impact, and the maximum position error could be reduced by 84%. The microstructure of the film under the S-curve motion profile shows smaller root-mean-square and scanning voltage amplitude under an atomic force microscope, which verifies the effectiveness of the S-curve motion profile in reducing the residual vibration and stabilizing the gap distance between the injector and the substrate. The film deposition rate could reach 100 nm/min while maintaining good uniformity without obvious periodic patterns on the surface.

  4. An Integrated Processing Strategy for Mountain Glacier Motion Monitoring Based on SAR Images

    Ruan, Z.; Yan, S.; Liu, G.; LV, M.

    2017-12-01

    Mountain glacier dynamic variables are important parameters in studies of environment and climate change in High Mountain Asia. Due to the increasing events of abnormal glacier-related hazards, research of monitoring glacier movements has attracted more interest during these years. Glacier velocities are sensitive and changing fast under complex conditions of high mountain regions, which implies that analysis of glacier dynamic changes requires comprehensive and frequent observations with relatively high accuracy. Synthetic aperture radar (SAR) has been successfully exploited to detect glacier motion in a number of previous studies, usually with pixel-tracking and interferometry methods. However, the traditional algorithms applied to mountain glacier regions are constrained by the complex terrain and diverse glacial motion types. Interferometry techniques are prone to fail in mountain glaciers because of their narrow size and the steep terrain, while pixel-tracking algorithm, which is more robust in high mountain areas, is subject to accuracy loss. In order to derive glacier velocities continually and efficiently, we propose a modified strategy to exploit SAR data information for mountain glaciers. In our approach, we integrate a set of algorithms for compensating non-glacial-motion-related signals which exist in the offset values retrieved by sub-pixel cross-correlation of SAR image pairs. We exploit modified elastic deformation model to remove the offsets associated with orbit and sensor attitude, and for the topographic residual offset we utilize a set of operations including DEM-assisted compensation algorithm and wavelet-based algorithm. At the last step of the flow, an integrated algorithm combining phase and intensity information of SAR images will be used to improve regional motion results failed in cross-correlation related processing. The proposed strategy is applied to the West Kunlun Mountain and Muztagh Ata region in western China using ALOS

  5. Neural Integration of Information Specifying Human Structure from Form, Motion, and Depth

    Jackson, Stuart; Blake, Randolph

    2010-01-01

    Recent computational models of biological motion perception operate on ambiguous two-dimensional representations of the body (e.g., snapshots, posture templates) and contain no explicit means for disambiguating the three-dimensional orientation of a perceived human figure. Are there neural mechanisms in the visual system that represent a moving human figure’s orientation in three dimensions? To isolate and characterize the neural mechanisms mediating perception of biological motion, we used an adaptation paradigm together with bistable point-light (PL) animations whose perceived direction of heading fluctuates over time. After exposure to a PL walker with a particular stereoscopically defined heading direction, observers experienced a consistent aftereffect: a bistable PL walker, which could be perceived in the adapted orientation or reversed in depth, was perceived predominantly reversed in depth. A phase-scrambled adaptor produced no aftereffect, yet when adapting and test walkers differed in size or appeared on opposite sides of fixation aftereffects did occur. Thus, this heading direction aftereffect cannot be explained by local, disparity-specific motion adaptation, and the properties of scale and position invariance imply higher-level origins of neural adaptation. Nor is disparity essential for producing adaptation: when suspended on top of a stereoscopically defined, rotating globe, a context-disambiguated “globetrotter” was sufficient to bias the bistable walker’s direction, as were full-body adaptors. In sum, these results imply that the neural signals supporting biomotion perception integrate information on the form, motion, and three-dimensional depth orientation of the moving human figure. Models of biomotion perception should incorporate mechanisms to disambiguate depth ambiguities in two-dimensional body representations. PMID:20089892

  6. Self-Organizing Neural Integration of Pose-Motion Features for Human Action Recognition

    German Ignacio Parisi

    2015-06-01

    Full Text Available The visual recognition of complex, articulated human movements is fundamental for a wide range of artificial systems oriented towards human-robot communication, action classification, and action-driven perception. These challenging tasks may generally involve the processing of a huge amount of visual information and learning-based mechanisms for generalizing a set of training actions and classifying new samples. To operate in natural environments, a crucial property is the efficient and robust recognition of actions, also under noisy conditions caused by, for instance, systematic sensor errors and temporarily occluded persons. Studies of the mammalian visual system and its outperforming ability to process biological motion information suggest separate neural pathways for the distinct processing of pose and motion features at multiple levels and the subsequent integration of these visual cues for action perception. We present a neurobiologically-motivated approach to achieve noise-tolerant action recognition in real time. Our model consists of self-organizing Growing When Required (GWR networks that obtain progressively generalized representations of sensory inputs and learn inherent spatiotemporal dependencies. During the training, the GWR networks dynamically change their topological structure to better match the input space. We first extract pose and motion features from video sequences and then cluster actions in terms of prototypical pose-motion trajectories. Multi-cue trajectories from matching action frames are subsequently combined to provide action dynamics in the joint feature space. Reported experiments show that our approach outperforms previous results on a dataset of full-body actions captured with a depth sensor, and ranks among the best 21 results for a public benchmark of domestic daily actions.

  7. The path integral formulation of fractional Brownian motion for the general Hurst exponent

    Calvo, I; Sanchez, R

    2008-01-01

    In 1995, Sebastian (1995 J. Phys. A: Math. Gen. 28 4305) gave a path integral computation of the propagator of subdiffusive fractional Brownian motion (fBm), i.e. fBm with a Hurst or self-similarity exponent H element of (0, 1/2). The extension of Sebastian's calculation to superdiffusion, H element of (1/2, 1], becomes however quite involved due to the appearance of additional boundary conditions on fractional derivatives of the path. In this communication, we address the construction of the path integral representation in a different fashion, which allows us to treat both subdiffusion and superdiffusion on an equal footing. The derivation of the propagator of fBm for the general Hurst exponent is then performed in a neat and unified way. (fast track communication)

  8. Beta, but not gamma, band oscillations index visual form-motion integration.

    Charles Aissani

    Full Text Available Electrophysiological oscillations in different frequency bands co-occur with perceptual, motor and cognitive processes but their function and respective contributions to these processes need further investigations. Here, we recorded MEG signals and seek for percept related modulations of alpha, beta and gamma band activity during a perceptual form/motion integration task. Participants reported their bound or unbound perception of ambiguously moving displays that could either be seen as a whole square-like shape moving along a Lissajou's figure (bound percept or as pairs of bars oscillating independently along cardinal axes (unbound percept. We found that beta (15-25 Hz, but not gamma (55-85 Hz oscillations, index perceptual states at the individual and group level. The gamma band activity found in the occipital lobe, although significantly higher during visual stimulation than during base line, is similar in all perceptual states. Similarly, decreased alpha activity during visual stimulation is not different for the different percepts. Trial-by-trial classification of perceptual reports based on beta band oscillations was significant in most observers, further supporting the view that modulation of beta power reliably index perceptual integration of form/motion stimuli, even at the individual level.

  9. THE INTEGRATION PROCESS MERCOSUR IN 2007 BY MODEL OF GLOBAL DIMENSION OF REGIONAL INTEGRATION

    André Bechlin

    2013-04-01

    Full Text Available This paper aimed to analyze the advance of the regional integration process in the MERCOSUR (Southern Common Market, using a model developed for Professor Mario Ruiz Estrada, of the College of Economy and Administration of the University of Kuala Lumpur in Malaysia, the GDRI (Global Dimension of Regional Integration Model and that as characteristic has differentiated the use of other variable for analysis, that not specifically of economic origin, derivatives of the evolution of the commerce processes. When inferring and comparing the external performance of the economies that compose the Mercosur, evaluating itself the impacts of the advance of the process of regional and commercial integration, are evidents the inequalities that exist in the block. However, a common evolution is observed, in the direction of intensification of the integration between the economies, mainly after the process of opening lived for the continent, beyond the advance of the integration in the context of the Mercosur, from the decade of 1990. The analyzed data show that, in the generality, these economies are if integrating to the world-wide market, and in parallel, accenting the integration degree enters the members of the block.

  10. Modeling Cancer Metastasis using Global, Quantitative and Integrative Network Biology

    Schoof, Erwin; Erler, Janine

    understanding of molecular processes which are fundamental to tumorigenesis. In Article 1, we propose a novel framework for how cancer mutations can be studied by taking into account their effect at the protein network level. In Article 2, we demonstrate how global, quantitative data on phosphorylation dynamics...... can be generated using MS, and how this can be modeled using a computational framework for deciphering kinase-substrate dynamics. This framework is described in depth in Article 3, and covers the design of KinomeXplorer, which allows the prediction of kinases responsible for modulating observed...... phosphorylation dynamics in a given biological sample. In Chapter III, we move into Integrative Network Biology, where, by combining two fundamental technologies (MS & NGS), we can obtain more in-depth insights into the links between cellular phenotype and genotype. Article 4 describes the proof...

  11. INTEGRATED PRODUCT AND ENTERPRISE DESIGN FOR GLOBAL COMPETITIVENESS

    N.D. Du Preez

    2012-01-01

    Full Text Available This paper presentsan overview of the challenge to integrate product and process life cycles in maintaining global competitiveness of an enterprise and proposes IEKOS as a possible solution . It provides the reader with a framework of two virtual life cycles which create a problem solving matrix for the industrial engineer. In this matrix, bordered by the virtual enterprise life cycle and the virtual product life cycles, the business functions of analyze, design deploy and operate are predominantly functions executed by the, industrial engineer. The different phases of each life cycle serves as a framework to a virtual industrial engineering toolkit providing access to detailed functions, formats, examples and a series of software and other "tools" available to the industrial engineer.
    In conclusion a brief overview is provided of the progress of the IEKOS toolkit which is under development at the department of Industrial Engineering at Stellenbosch University.

  12. Domestic change in the face of European Integration and Globalization

    Lynggaard, Kennet

    2011-01-01

    epistemological concerns within the Europeanization literature, this in-the-making research agenda is also faced with a number of methodological challenges. This article deals with some of the most pressing methodological challenges we face when conducting empirical research and moving towards more comprehensive...... accounts of domestic change. Drawing on methodologies known from comparative politics and discourse analysis, the article argues in favour of three methodological moves: (1) from top-down towards bottom-up methodological set-ups; (2) from counterfactual analysis towards compound temporal comparative......Before the early 2000s, research on Europeanization and globalization developed largely independently of each other. Since then a limited, yet increasing, number of studies have shown an interest in investigating and differentiating between the domestic implications of European integration - known...

  13. Integrating Globality and Locality for Robust Representation Based Classification

    Zheng Zhang

    2014-01-01

    Full Text Available The representation based classification method (RBCM has shown huge potential for face recognition since it first emerged. Linear regression classification (LRC method and collaborative representation classification (CRC method are two well-known RBCMs. LRC and CRC exploit training samples of each class and all the training samples to represent the testing sample, respectively, and subsequently conduct classification on the basis of the representation residual. LRC method can be viewed as a “locality representation” method because it just uses the training samples of each class to represent the testing sample and it cannot embody the effectiveness of the “globality representation.” On the contrary, it seems that CRC method cannot own the benefit of locality of the general RBCM. Thus we propose to integrate CRC and LRC to perform more robust representation based classification. The experimental results on benchmark face databases substantially demonstrate that the proposed method achieves high classification accuracy.

  14. Local and Global Illumination in the Volume Rendering Integral

    Max, N; Chen, M

    2005-10-21

    This article is intended as an update of the major survey by Max [1] on optical models for direct volume rendering. It provides a brief overview of the subject scope covered by [1], and brings recent developments, such as new shadow algorithms and refraction rendering, into the perspective. In particular, we examine three fundamentals aspects of direct volume rendering, namely the volume rendering integral, local illumination models and global illumination models, in a wavelength-independent manner. We review the developments on spectral volume rendering, in which visible light are considered as a form of electromagnetic radiation, optical models are implemented in conjunction with representations of spectral power distribution. This survey can provide a basis for, and encourage, new efforts for developing and using complex illumination models to achieve better realism and perception through optical correctness.

  15. Integrable motion of curves in self-consistent potentials: Relation to spin systems and soliton equations

    Myrzakulov, R.; Mamyrbekova, G.K.; Nugmanova, G.N.; Yesmakhanova, K.R. [Eurasian International Center for Theoretical Physics and Department of General and Theoretical Physics, Eurasian National University, Astana 010008 (Kazakhstan); Lakshmanan, M., E-mail: lakshman@cnld.bdu.ac.in [Centre for Nonlinear Dynamics, School of Physics, Bharathidasan University, Tiruchirapalli 620 024 (India)

    2014-06-13

    Motion of curves and surfaces in R{sup 3} lead to nonlinear evolution equations which are often integrable. They are also intimately connected to the dynamics of spin chains in the continuum limit and integrable soliton systems through geometric and gauge symmetric connections/equivalence. Here we point out the fact that a more general situation in which the curves evolve in the presence of additional self-consistent vector potentials can lead to interesting generalized spin systems with self-consistent potentials or soliton equations with self-consistent potentials. We obtain the general form of the evolution equations of underlying curves and report specific examples of generalized spin chains and soliton equations. These include principal chiral model and various Myrzakulov spin equations in (1+1) dimensions and their geometrically equivalent generalized nonlinear Schrödinger (NLS) family of equations, including Hirota–Maxwell–Bloch equations, all in the presence of self-consistent potential fields. The associated gauge equivalent Lax pairs are also presented to confirm their integrability. - Highlights: • Geometry of continuum spin chain with self-consistent potentials explored. • Mapping on moving space curves in R{sup 3} in the presence of potential fields carried out. • Equivalent generalized nonlinear Schrödinger (NLS) family of equations identified. • Integrability of identified nonlinear systems proved by deducing appropriate Lax pairs.

  16. Integrated management system - ground for the global performance

    Pereira Filho, Jorge Amorim

    2000-01-01

    Organizations working in the pursuit of a sustainable development must create and continuously update their management systems, in order to achieve harmonic and lasting global results, capable of satisfying partners and clients in short and long terms. Such an improvement can be obtained by integrating preexisting classic management models, applicable to organizations of all types and scales. The implementation of this unique resulting system obeys systematic steps of planning, development, checking and correction, aiming to continuously improve the management. It is in fact a very challenging process because it demands changing people minds, increasing the amount of work and learning of new skills. Though hard-working, such implementation is encouraged both by perceiving the necessity to attain the strategic objectives and by seeing that there are some requisites not yet fully covered by the present system. Finally, this improved management system results in a better global performance, recorded under four angles: financial, increased client satisfaction, better internal processes and continuous learning, driving the organization to be more competitive and successful in the future. (author)

  17. Motion estimation by integrated low cost system (vision and MEMS) for positioning of a scooter "Vespa"

    Guarnieri, A.; Milan, N.; Pirotti, F.; Vettore, A.

    2011-12-01

    In the automotive sector, especially in these last decade, a growing number of investigations have taken into account electronic systems to check and correct the behavior of drivers, increasing road safety. The possibility to identify with high accuracy the vehicle position in a mapping reference frame for driving directions and best-route analysis is also another topic which attracts lot of interest from the research and development sector. To reach the objective of accurate vehicle positioning and integrate response events, it is necessary to estimate time by time the position, orientation and velocity of the system. To this aim low cost GPS and MEMS (sensors can be used. In comparison to a four wheel vehicle, the dynamics of a two wheel vehicle (e.g. a scooter) feature a higher level of complexity. Indeed more degrees of freedom must be taken into account to describe the motion of the latter. For example a scooter can twist sideways, thus generating a roll angle. A slight pitch angle has to be considered as well, since wheel suspensions have a higher degree of motion with respect to four wheel vehicles. In this paper we present a method for the accurate reconstruction of the trajectory of a motorcycle ("Vespa" scooter), which can be used as alternative to the "classical" approach based on the integration of GPS and INS sensors. Position and orientation of the scooter are derived from MEMS data and images acquired by on-board digital camera. A Bayesian filter provides the means for integrating the data from MEMS-based orientation sensor and the GPS receiver.

  18. The study of key issues about integration of GNSS and strong-motion records for real-time earthquake monitoring

    Tu, Rui; Zhang, Pengfei; Zhang, Rui; Liu, Jinhai

    2016-08-01

    This paper has studied the key issues about integration of GNSS and strong-motion records for real-time earthquake monitoring. The validations show that the consistence of the coordinate system must be considered firstly to exclude the system bias between GNSS and strong-motion. The GNSS sampling rate is suggested about 1-5 Hz, and we should give the strong-motion's baseline shift with a larger dynamic noise as its variation is very swift. The initialization time of solving the baseline shift is less than one minute, and ambiguity resolution strategy is not greatly improved the solution. The data quality is very important for the solution, we advised to use multi-frequency and multi-system observations. These ideas give an important guide for real-time earthquake monitoring and early warning by the tight integration of GNSS and strong-motion records.

  19. Trends in Global and Regional Integration by means of Trade

    Iulia Monica Oehler-Șincai

    2014-04-01

    Full Text Available In the present paper we aim to emphasize several aspects of the economic integration realized through the channel of trade, from a double perspective. The first point of view is given by the formal framework, de jure, composed by the multitude of preferential trade agreements, while the second one, de facto, market-driven, is concretized by the global production networks. The first stance is exemplified through the agreements negotiated or concluded by the traditional trade powers, EU, US and Japan. Although, economically, EU is more present in Asia-Pacific than the US, the latter are politically more active and seem to gain ground. The second stance is underlined by means of the Asian integration specificity. East and South-East Asia represents the core of „Factory Asia” and is governed by the activity of the transnational corporations, their investment and cross-border networks, which makes the production process more fragmented and the regional economies more mutually dependent.

  20. Integrated fMRI Preprocessing Framework Using Extended Kalman Filter for Estimation of Slice-Wise Motion

    Basile Pinsard; Basile Pinsard; Basile Pinsard; Arnaud Boutin; Arnaud Boutin; Julien Doyon; Julien Doyon; Habib Benali; Habib Benali; Habib Benali

    2018-01-01

    Functional MRI acquisition is sensitive to subjects' motion that cannot be fully constrained. Therefore, signal corrections have to be applied a posteriori in order to mitigate the complex interactions between changing tissue localization and magnetic fields, gradients and readouts. To circumvent current preprocessing strategies limitations, we developed an integrated method that correct motion and spatial low-frequency intensity fluctuations at the level of each slice in order to better fit ...

  1. Integrating Equality - Globalization, Women's Rights, Son Preference and Human Trafficking

    Cho, Seo-Young

    2011-01-01

    Employing economic and social globalization indicators, we empirically analyze whether globalization affects women’s rights in the economic and social dimensions. Using panel data from 150 countries over the 1981-2008 period, we find that social globalization positively affects both women’s economic and social rights, while the impact of economic globalization disappears when controlling for social globalization. Furthermore, we find that social globalization also reduces ‘son preference’ pro...

  2. The Glory Program: Global Science from a Unique Spacecraft Integration

    Bajpayee Jaya; Durham, Darcie; Ichkawich, Thomas

    2006-01-01

    The Glory program is an Earth and Solar science mission designed to broaden science community knowledge of the environment. The causes and effects of global warming have become a concern in recent years and Glory aims to contribute to the knowledge base of the science community. Glory is designed for two functions: one is solar viewing to monitor the total solar irradiance and the other is observing the Earth s atmosphere for aerosol composition. The former is done with an active cavity radiometer, while the latter is accomplished with an aerosol polarimeter sensor to discern atmospheric particles. The Glory program is managed by NASA Goddard Space Flight Center (GSFC) with Orbital Sciences in Dulles, VA as the prime contractor for the spacecraft bus, mission operations, and ground system. This paper will describe some of the more unique features of the Glory program including the integration and testing of the satellite and instruments as well as the science data processing. The spacecraft integration and test approach requires extensive analysis and additional planning to ensure existing components are successfully functioning with the new Glory components. The science mission data analysis requires development of mission unique processing systems and algorithms. Science data analysis and distribution will utilize our national assets at the Goddard Institute for Space Studies (GISS) and the University of Colorado's Laboratory for Atmospheric and Space Physics (LASP). The Satellite was originally designed and built for the Vegetation Canopy Lidar (VCL) mission, which was terminated in the middle of integration and testing due to payload development issues. The bus was then placed in secure storage in 2001 and removed from an environmentally controlled container in late 2003 to be refurbished to meet the Glory program requirements. Functional testing of all the components was done as a system at the start of the program, very different from a traditional program

  3. THE INTEGRATION OF EDUCATION AND SCIENCE AS A GLOBAL PROBLEM

    Anatoliy I. Rakitov

    2016-09-01

    Full Text Available Introduction: mankind is on the edge of a new techno-technological and socio-economical revolution generated by robotization and automation in all spheres of individual and socio-economical activity. Among numerous conceptions of global development only the conception of the knowledge-based society is the most adequate to contemporary terms. As the higher education and science are the main source of knowledge adequate to contemporary terms then their integration should be investigated. Materials and Methods: the material for this investigation was gathered as from individual experience in science and pedagogical activity of the author which were earlier published in hundreds of articles and fifteen monograph translated in eleven languages, as the materials of Moscow city seminar, the results of which were published in annual “Science of science investigations”. This annual has been editing since 2004 and the author is the editor-in-chief of this edition. Also has been used other sources from different editions. The method of comparative analysis was used. Results: the author put forward the conception of inevitable integration of higher school and research institutions and forming a new structure – science-education consortium. Only such united structure can significantly rise both scientific researchers and higher education. And as a result, it will rise publishing activity and application of scientific researchers in real econ omy, social sphere, technological leadership. Discussion and Conclusions: conception put forward in this article fragmentary has been published by author earlier and initiated discussion in scientific press, which was reflected in home RISC and abroad citation indexes. The author proclaims the inevitability of realization of the suggested by him conception of the utmost integration of science and higher education.

  4. Integrated Decision Support for Global Environmental Change Adaptation

    Kumar, S.; Cantrell, S.; Higgins, G. J.; Marshall, J.; VanWijngaarden, F.

    2011-12-01

    Environmental changes are happening now that has caused concern in many parts of the world; particularly vulnerable are the countries and communities with limited resources and with natural environments that are more susceptible to climate change impacts. Global leaders are concerned about the observed phenomena and events such as Amazon deforestation, shifting monsoon patterns affecting agriculture in the mountain slopes of Peru, floods in Pakistan, water shortages in Middle East, droughts impacting water supplies and wildlife migration in Africa, and sea level rise impacts on low lying coastal communities in Bangladesh. These environmental changes are likely to get exacerbated as the temperatures rise, the weather and climate patterns change, and sea level rise continues. Large populations and billions of dollars of infrastructure could be affected. At Northrop Grumman, we have developed an integrated decision support framework for providing necessary information to stakeholders and planners to adapt to the impacts of climate variability and change at the regional and local levels. This integrated approach takes into account assimilation and exploitation of large and disparate weather and climate data sets, regional downscaling (dynamic and statistical), uncertainty quantification and reduction, and a synthesis of scientific data with demographic and economic data to generate actionable information for the stakeholders and decision makers. Utilizing a flexible service oriented architecture and state-of-the-art visualization techniques, this information can be delivered via tailored GIS portals to meet diverse set of user needs and expectations. This integrated approach can be applied to regional and local risk assessments, predictions and decadal projections, and proactive adaptation planning for vulnerable communities. In this paper we will describe this comprehensive decision support approach with selected applications and case studies to illustrate how this

  5. Integrated assessment of the global warming problem. A decision-analytical approach

    Van Lenthe, J.; Hendrickx, L.; Vlek, C.A.J.

    1995-01-01

    The project on the title subject aims at developing a policy-oriented methodology for the integrated assessment of the global warming problem. Decision analysis in general and influence diagrams in particular appear to constitute an appropriate integrated assessment methodology. The influence-diagram approach is illustrated at a preliminary integrated modeling of the global warming problem. In next stages of the research, attention will be shifted from the methodology of integrated assessment to the contents of integrated models. 4 figs., 5 refs

  6. The Temporal Dynamics of Feature Integration for Color, form, and Motion

    KS Pilz

    2012-07-01

    Full Text Available When two similar visual stimuli are presented in rapid succession, only their fused image is perceived, without having conscious access to the single stimuli. Such feature fusion occurs both for color (eg, Efron1973 and form (eg, Scharnowski et al 2007. For verniers, the fusion process lasts for more than 400 ms, as has been shown using TMS (Scharnowski et al 2009. In three experiments, we used light masks to investigate the time course of feature fusion for color, form, and motion. In experiment one, two verniers were presented in rapid succession with opposite offset directions. Subjects had to indicate the offset direction of the vernier. In a second experiment, a red and a green disk were presented in rapid succession, and subjects had to indicate whether the fused, yellow disk appeared rather than red or green. In a third experiment, three frames of random dots were presented successively. The first two frames created a percept of apparent motion to the upper right; and the last two frames, one to the upper left or vice versa. Subjects had to indicate the direction of motion. All stimuli were presented foveally. In all three experiments, we first balanced performance so that neither the first nor the second stimulus dominated the fused percept. In a second step, a light mask was presented either before, during, or after stimulus presentation. Depending on presentation time, the light masks modulated the fusion process so that either the first or the second stimulus dominated the percept. Our results show that unconscious feature fusion lasts more than five times longer than the actual stimulus duration, which indicates that individual features are stored for a substantial amount of time before they are integrated.

  7. A global first integral for certain dynamical systems and related remarks

    Gonzalez-Gascon, F.

    1977-01-01

    A global first integral for certain dynamical systems and the related remarks are presented. In particular, it is shown that for these dynamical systems by introducing the (intrinsic) definition of the divergence of a vector field defined on an orientable differentiable manifold, the first integral, i.e. the (intrinsic) divergence of a vector field is now, automatically, a global first integral. (author)

  8. Application of data assimilation methods for analysis and integration of observed and modeled Arctic Sea ice motions

    Meier, Walter Neil

    This thesis demonstrates the applicability of data assimilation methods to improve observed and modeled ice motion fields and to demonstrate the effects of assimilated motion on Arctic processes important to the global climate and of practical concern to human activities. Ice motions derived from 85 GHz and 37 GHz SSM/I imagery and estimated from two-dimensional dynamic-thermodynamic sea ice models are compared to buoy observations. Mean error, error standard deviation, and correlation with buoys are computed for the model domain. SSM/I motions generally have a lower bias, but higher error standard deviations and lower correlation with buoys than model motions. There are notable variations in the statistics depending on the region of the Arctic, season, and ice characteristics. Assimilation methods are investigated and blending and optimal interpolation strategies are implemented. Blending assimilation improves error statistics slightly, but the effect of the assimilation is reduced due to noise in the SSM/I motions and is thus not an effective method to improve ice motion estimates. However, optimal interpolation assimilation reduces motion errors by 25--30% over modeled motions and 40--45% over SSM/I motions. Optimal interpolation assimilation is beneficial in all regions, seasons and ice conditions, and is particularly effective in regimes where modeled and SSM/I errors are high. Assimilation alters annual average motion fields. Modeled ice products of ice thickness, ice divergence, Fram Strait ice volume export, transport across the Arctic and interannual basin averages are also influenced by assimilated motions. Assimilation improves estimates of pollutant transport and corrects synoptic-scale errors in the motion fields caused by incorrect forcings or errors in model physics. The portability of the optimal interpolation assimilation method is demonstrated by implementing the strategy in an ice thickness distribution (ITD) model. This research presents an

  9. MOCA: A Low-Power, Low-Cost Motion Capture System Based on Integrated Accelerometers

    Elisabetta Farella

    2007-01-01

    Full Text Available Human-computer interaction (HCI and virtual reality applications pose the challenge of enabling real-time interfaces for natural interaction. Gesture recognition based on body-mounted accelerometers has been proposed as a viable solution to translate patterns of movements that are associated with user commands, thus substituting point-and-click methods or other cumbersome input devices. On the other hand, cost and power constraints make the implementation of a natural and efficient interface suitable for consumer applications a critical task. Even though several gesture recognition solutions exist, their use in HCI context has been poorly characterized. For this reason, in this paper, we consider a low-cost/low-power wearable motion tracking system based on integrated accelerometers called motion capture with accelerometers (MOCA that we evaluated for navigation in virtual spaces. Recognition is based on a geometric algorithm that enables efficient and robust detection of rotational movements. Our objective is to demonstrate that such a low-cost and a low-power implementation is suitable for HCI applications. To this purpose, we characterized the system from both a quantitative point of view and a qualitative point of view. First, we performed static and dynamic assessment of movement recognition accuracy. Second, we evaluated the effectiveness of user experience using a 3D game application as a test bed.

  10. Documenting the NASA Armstrong Flight Research Center Oblate Earth Simulation Equations of Motion and Integration Algorithm

    Clarke, R.; Lintereur, L.; Bahm, C.

    2016-01-01

    A desire for more complete documentation of the National Aeronautics and Space Administration (NASA) Armstrong Flight Research Center (AFRC), Edwards, California legacy code used in the core simulation has led to this e ort to fully document the oblate Earth six-degree-of-freedom equations of motion and integration algorithm. The authors of this report have taken much of the earlier work of the simulation engineering group and used it as a jumping-o point for this report. The largest addition this report makes is that each element of the equations of motion is traced back to first principles and at no point is the reader forced to take an equation on faith alone. There are no discoveries of previously unknown principles contained in this report; this report is a collection and presentation of textbook principles. The value of this report is that those textbook principles are herein documented in standard nomenclature that matches the form of the computer code DERIVC. Previous handwritten notes are much of the backbone of this work, however, in almost every area, derivations are explicitly shown to assure the reader that the equations which make up the oblate Earth version of the computer routine, DERIVC, are correct.

  11. Fuel motion in overpower tests of metallic integral fast reactor fuel

    Rhodes, E.A.; Bauer, T.H.; Stanford, G.S.; Regis, J.P.; Dickerman, C.E.

    1992-01-01

    In this paper results from hodoscope data analyses are presented for transient overpower (TOP) tests M5, M6, and M7 at the Transient Reactor Test Facility, with emphasis on transient feedback mechanisms, including prefailure expansion at the tops of the fuel pins, subsequent dispersive axial fuel motion, and losses in relative worth of the fuel pins during the tests. Tests M5 and M6 were the first TOP tests of margin to cladding breach and prefailure elongation of D9-clad ternary (U-Pu-Zr) integral fast reactor-type fuel. Test M7 extended these results to high-burnup fuel and also initiated transient testing of HT-9-clad binary (U-Zr) Fast Flux Test Facility driver fuel. Results show significant prefailure negative reactivity feedback and strongly negative feedback from fuel driven to failure

  12. Integrated direct/indirect adaptive robust motion trajectory tracking control of pneumatic cylinders

    Meng, Deyuan; Tao, Guoliang; Zhu, Xiaocong

    2013-09-01

    This paper studies the precision motion trajectory tracking control of a pneumatic cylinder driven by a proportional-directional control valve. An integrated direct/indirect adaptive robust controller is proposed. The controller employs a physical model based indirect-type parameter estimation to obtain reliable estimates of unknown model parameters, and utilises a robust control method with dynamic compensation type fast adaptation to attenuate the effects of parameter estimation errors, unmodelled dynamics and disturbances. Due to the use of projection mapping, the robust control law and the parameter adaption algorithm can be designed separately. Since the system model uncertainties are unmatched, the recursive backstepping technology is adopted to design the robust control law. Extensive comparative experimental results are presented to illustrate the effectiveness of the proposed controller and its performance robustness to parameter variations and sudden disturbances.

  13. An application of oscillation damped motion for suspended payloads to the advanced integrated maintenance system

    Noakes, M.W.; Petterson, B.J.; Werner, J.C.

    1990-01-01

    Transportation of objects using overhead cranes can induce pendulum motion of the object, which usually must be damped or allowed to decay before the next process can take place. Recent work at Sandia National Laboratories (SNL) has shown that oscillation damped transport and swing-free stops are possible by properly programming the acceleration of the transporting crane. This paper reviews the theory associated with oscillation-damped trajectories for simply suspended objects and describes a specific, full-scale implementation of the damped oscillation methods for the Oak Ridge National Laboratory (ORNL) Advanced Integrated Maintenance System (AIMS). Hardware and software requirements and constraints for proper operation are discussed. Finally, test results and lessons learned are presented. 5 refs., 4 figs

  14. GLOFRIM v1.0-A globally applicable computational framework for integrated hydrological-hydrodynamic modelling

    Hoch, Jannis M.; Neal, Jeffrey C.; Baart, Fedor; Van Beek, Rens; Winsemius, Hessel C.; Bates, Paul D.; Bierkens, Marc F.P.

    2017-01-01

    We here present GLOFRIM, a globally applicable computational framework for integrated hydrological-hydrodynamic modelling. GLOFRIM facilitates spatially explicit coupling of hydrodynamic and hydrologic models and caters for an ensemble of models to be coupled. It currently encompasses the global

  15. Teaching Resources and Instructor Professional Development for Integrating Laser Scanning, Structure from Motion, and GPS Surveying into Undergraduate Field Courses

    Pratt-Sitaula, B.; Charlevoix, D. J.; Douglas, B. J.; Crosby, B. T.; Crosby, C. J.; Lauer, I. H.; Shervais, K.

    2017-12-01

    Field experiences have long been considered an integral part of geoscience learning. However, as data acquisition technologies evolve, undergraduate field courses need to keep pace so students gain exposure to new technologies relevant to the modern workforce. Maintaining expertise on new technologies is also challenging to established field education programs. Professional development and vetted curriculum present an opportunity to advance student exposure to new geoscience data acquisition technology. The GEodesy Tools for Societal Issues (GETSI) Field Collection, funded by NSF's Improving Undergraduate STEM Education program, addresses these needs in geodesy field education. Geodesy is the science of accurately measuring Earth's size, shape, orientation, mass distribution and the variations of these with time. Modern field geodesy methods include terrestrial laser scanning (TLS), kinematic and static GPS/GNSS surveying (global positioning system/global navigation satellite system), and structure from motion (SfM) photogrammetry. The GETSI Field Collection is a collaborative project between UNAVCO, Indiana University, and Idaho State University. The project is provides curriculum modules and instructor training (in the form of short courses) to facilitate the inclusion of SfM, TLS, and GPS surveying into geoscience courses with field components. The first module - Analyzing High Resolution Topography with TLS and SfM - is available via SERC; (serc.carleton.edu/getsi/teaching_materials/high-rez-topo) the second module - "High Precision Positioning with Static and Kinematic GPS/GNSS" - will be published in 2018. The module development and assessment follows the standards of the InTeGrate Project (an NSF STEP Center)previously tested on geodesy content in the GETSI classroom collection (serc.carleton.edu/getsi). This model emphasizes use of best practices in STEM education, including situating learning in the context of societal importance. Analysis of student work

  16. A 'special effort' to provide improved sounding and cloud-motion wind data for FGGE. [First GARP Global Experiment

    Greaves, J. R.; Dimego, G.; Smith, W. L.; Suomi, V. E.

    1979-01-01

    Enhancement and editing of high-density cloud motion wind assessments and research satellite soundings have been necessary to improve the quality of data used in The Global Weather Experiment. Editing operations are conducted by a man-computer interactive data access system. Editing will focus on such inputs as non-US satellite data, NOAA operational sounding and wind data sets, wind data from the Indian Ocean satellite, dropwindsonde data, and tropical mesoscale wind data. Improved techniques for deriving cloud heights and higher resolution sounding in meteorologically active areas are principal parts of the data enhancement program.

  17. GLobal Integrated Design Environment (GLIDE): A Concurrent Engineering Application

    McGuire, Melissa L.; Kunkel, Matthew R.; Smith, David A.

    2010-01-01

    The GLobal Integrated Design Environment (GLIDE) is a client-server software application purpose-built to mitigate issues associated with real time data sharing in concurrent engineering environments and to facilitate discipline-to-discipline interaction between multiple engineers and researchers. GLIDE is implemented in multiple programming languages utilizing standardized web protocols to enable secure parameter data sharing between engineers and researchers across the Internet in closed and/or widely distributed working environments. A well defined, HyperText Transfer Protocol (HTTP) based Application Programming Interface (API) to the GLIDE client/server environment enables users to interact with GLIDE, and each other, within common and familiar tools. One such common tool, Microsoft Excel (Microsoft Corporation), paired with its add-in API for GLIDE, is discussed in this paper. The top-level examples given demonstrate how this interface improves the efficiency of the design process of a concurrent engineering study while reducing potential errors associated with manually sharing information between study participants.

  18. An Integrated Model of Motion, Steering, Positioning and Stabilization of an Unmanned Autonomous Maritime Vehicle

    Miroslaw Gerigk

    2015-12-01

    Full Text Available In the paper the aim of an interdisciplinary research is presented. The research method is introduced. An object the unmanned autonomous maritime vehicle is briefly described. The key research problem concerns a combined model of the vehicle motion including the loads of lift and hydrodynamic nature. The model takes into account the gravity and displacement forces, resistance and thrust forces, lift and other hydrodynamic forces. One of the major research tasks is to precisely predict the position of the vehicle. To do that an integrated model of acquiring, analyzing and processing the signals is necessary. The processed signals may then be used for the precise steering of the vehicle. The vehicle should be equipped with a stabilization system. Some information on an integrated steering, positioning and stabilization system of the vehicle is briefly presented in the paper. Such the system enables to obtain a fully autonomous vehicle. Some information on the propulsion and underwater energy supply systems are presented in the paper, too.

  19. A systematic method for constructing time discretizations of integrable lattice systems: local equations of motion

    Tsuchida, Takayuki

    2010-01-01

    We propose a new method for discretizing the time variable in integrable lattice systems while maintaining the locality of the equations of motion. The method is based on the zero-curvature (Lax pair) representation and the lowest-order 'conservation laws'. In contrast to the pioneering work of Ablowitz and Ladik, our method allows the auxiliary dependent variables appearing in the stage of time discretization to be expressed locally in terms of the original dependent variables. The time-discretized lattice systems have the same set of conserved quantities and the same structures of the solutions as the continuous-time lattice systems; only the time evolution of the parameters in the solutions that correspond to the angle variables is discretized. The effectiveness of our method is illustrated using examples such as the Toda lattice, the Volterra lattice, the modified Volterra lattice, the Ablowitz-Ladik lattice (an integrable semi-discrete nonlinear Schroedinger system) and the lattice Heisenberg ferromagnet model. For the modified Volterra lattice, we also present its ultradiscrete analogue.

  20. Harmonic analysis and global solvability of a differential operator invariant on motion groups and semi-simple Lie groups

    El-Hussein, K.

    1991-08-01

    Let V be a real finite dimensional vector space and let K be a connected compact Lie group, which acts on V by means of a continuous linear representation ρ. Let G=V x p K be the motion group which is the semi-direct product of V by K and let P be an invariant differential operator on G. In this paper we give a necessary and sufficient condition for the global solvability of P on G. Now let G be a connected semi-simple Lie group with finite centre and let P be an invariant differential operator on G. We give also a necessary and sufficient condition for the global solvability of P on G. (author). 8 refs

  1. Integration of visual and non-visual self-motion cues during voluntary head movements in the human brain.

    Schindler, Andreas; Bartels, Andreas

    2018-05-15

    Our phenomenological experience of the stable world is maintained by continuous integration of visual self-motion with extra-retinal signals. However, due to conventional constraints of fMRI acquisition in humans, neural responses to visuo-vestibular integration have only been studied using artificial stimuli, in the absence of voluntary head-motion. We here circumvented these limitations and let participants to move their heads during scanning. The slow dynamics of the BOLD signal allowed us to acquire neural signal related to head motion after the observer's head was stabilized by inflatable aircushions. Visual stimuli were presented on head-fixed display goggles and updated in real time as a function of head-motion that was tracked using an external camera. Two conditions simulated forward translation of the participant. During physical head rotation, the congruent condition simulated a stable world, whereas the incongruent condition added arbitrary lateral motion. Importantly, both conditions were precisely matched in visual properties and head-rotation. By comparing congruent with incongruent conditions we found evidence consistent with the multi-modal integration of visual cues with head motion into a coherent "stable world" percept in the parietal operculum and in an anterior part of parieto-insular cortex (aPIC). In the visual motion network, human regions MST, a dorsal part of VIP, the cingulate sulcus visual area (CSv) and a region in precuneus (Pc) showed differential responses to the same contrast. The results demonstrate for the first time neural multimodal interactions between precisely matched congruent versus incongruent visual and non-visual cues during physical head-movement in the human brain. The methodological approach opens the path to a new class of fMRI studies with unprecedented temporal and spatial control over visuo-vestibular stimulation. Copyright © 2018 Elsevier Inc. All rights reserved.

  2. Dominance of free wall radial motion in global right ventricular function of heart transplant recipients.

    Lakatos, Bálint Károly; Tokodi, Márton; Assabiny, Alexandra; Tősér, Zoltán; Kosztin, Annamária; Doronina, Alexandra; Rácz, Kristóf; Koritsánszky, Kinga Bianka; Berzsenyi, Viktor; Németh, Endre; Sax, Balázs; Kovács, Attila; Merkely, Béla

    2018-03-01

    Assessment of right ventricular (RV) function using conventional echocardiography might be inadequate as the radial motion of the RV free wall is often neglected. Our aim was to quantify the longitudinal and the radial components of RV function using three-dimensional (3D) echocardiography in heart transplant (HTX) recipients. Fifty-one HTX patients in stable cardiovascular condition without history of relevant rejection episode or chronic allograft vasculopathy and 30 healthy volunteers were enrolled. RV end-diastolic (EDV) volume and total ejection fraction (TEF) were measured by 3D echocardiography. Furthermore, we quantified longitudinal (LEF) and radial ejection fraction (REF) by decomposing the motion of the RV using the ReVISION method. RV EDV did not differ between groups (HTX vs control; 96 ± 27 vs 97 ± 2 mL). In HTX patients, TEF was lower, however, tricuspid annular plane systolic excursion (TAPSE) decreased to a greater extent (TEF: 47 ± 7 vs 54 ± 4% [-13%], TAPSE: 11 ± 5 vs 21 ± 4 mm [-48%], P < .0001). In HTX patients, REF/TEF ratio was significantly higher compared to LEF/TEF (REF/TEF vs LEF/TEF: 0.58 ± 0.10 vs 0.27 ± 0.08, P < .0001), while in controls the REF/TEF and LEF/TEF ratio was similar (0.45 ± 0.07 vs 0.47 ± 0.07). Current results confirm the superiority of radial motion in determining RV function in HTX patients. Parameters incorporating the radial motion are recommended to assess RV function in HTX recipients. © 2018 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  3. Estimation of Subdaily Polar Motion with the Global Positioning System During the Spoch '92 Campaign

    Ibanez-Meier, R.; Freedman, A. P.; Herring, T. A.; Gross, R. S.; Lichten, S. M.; Lindqwister, U. J.

    1994-01-01

    Data collected over six days from a worldwide Global Positioning System (GPS) tracking network during the Epoch '92 campaign are used to estimate variations of the Earth's pole position every 30 minutes.

  4. Integrating Global Hydrology Into Graduate Engineering Education and Research

    Griffis, V. W.

    2007-12-01

    Worldwide, polluted water affects the health of 1.2 billion people and contributes to the death of 15 million children under five every year. In addition poor environmental quality contributes to 25 per cent of all preventable ill health in the world. To address some of these problems, at the 2002 World Summit on Sustainable Development, the world community set the goal of halving, by the year 2015, the proportion of people without access to safe drinking water and basic sanitation. Solving sanitation and water resource management problems in any part of the world presents an interdisciplinary, complex challenge. However, when we attempt to solve these problems in an international context, our technical approaches must be tempered with cultural sensitivity and extraordinary management strategies. To meet this challenge, Michigan Tech has developed a unique global partnership with the U.S. Peace Corps to address our acknowledgement of the importance of placing engineering solutions in a global context. The program has graduated 30 students. Program enrollment is now over 30 and over 20 countries have hosted our students. The objective of this presentation is to demonstrate how this unique partnership can be integrated with graduate engineering education and research and also show how such a program may attract a more diverse student population into engineering. All graduate students enrolled in our Master's International Program in Civil and Environmental Engineering must complete specific coursework requirements before departing for their international experience. In CE5993 (Field Engineering in the Developing World) students learn to apply concepts of sustainable development and appropriate technology in the developing world. In FW5770 (Rural Community Development Planning and Analysis) students learn how one involves a community in the decision making process. A common theme in both courses is the role of woman in successful development projects. Technical

  5. Managing the tensions in integrating global organisations : The role of performance management systems

    Busco, C.; Giovannoni, E.; Scapens, R.W.

    The paper explores the role of performance management systems (PMSs) in integrating global organisations (GOs). It investigates the ways in which the diverse entities that comprise a GO can be co-ordinated and integrated to achieve a global unity of effort, while leaving space for local adaptation,

  6. Collective motions of globally coupled oscillators and some probability distributions on circle

    Jaćimović, Vladimir [Faculty of Natural Sciences and Mathematics, University of Montenegro, Cetinjski put, bb., 81000 Podgorica (Montenegro); Crnkić, Aladin, E-mail: aladin.crnkic@hotmail.com [Faculty of Technical Engineering, University of Bihać, Ljubijankićeva, bb., 77000 Bihać, Bosnia and Herzegovina (Bosnia and Herzegovina)

    2017-06-28

    In 2010 Kato and Jones described a new family of probability distributions on circle, obtained as Möbius transformation of von Mises distribution. We present the model demonstrating that these distributions appear naturally in study of populations of coupled oscillators. We use this opportunity to point out certain relations between Directional Statistics and collective motion of coupled oscillators. - Highlights: • We specify probability distributions on circle that arise in Kuramoto model. • We study how the mean-field coupling affects the shape of distribution of phases. • We discuss potential applications in some experiments on cell cycle. • We apply Directional Statistics to study collective dynamics of coupled oscillators.

  7. Global motions exhibited by proteins in micro- to milliseconds simulations concur with anisotropic network model predictions

    Gur, M.; Zomot, E.; Bahar, I.

    2013-09-01

    The Anton supercomputing technology recently developed for efficient molecular dynamics simulations permits us to examine micro- to milli-second events at full atomic resolution for proteins in explicit water and lipid bilayer. It also permits us to investigate to what extent the collective motions predicted by network models (that have found broad use in molecular biophysics) agree with those exhibited by full-atomic long simulations. The present study focuses on Anton trajectories generated for two systems: the bovine pancreatic trypsin inhibitor, and an archaeal aspartate transporter, GltPh. The former, a thoroughly studied system, helps benchmark the method of comparative analysis, and the latter provides new insights into the mechanism of function of glutamate transporters. The principal modes of motion derived from both simulations closely overlap with those predicted for each system by the anisotropic network model (ANM). Notably, the ANM modes define the collective mechanisms, or the pathways on conformational energy landscape, that underlie the passage between the crystal structure and substates visited in simulations. In particular, the lowest frequency ANM modes facilitate the conversion between the most probable substates, lending support to the view that easy access to functional substates is a robust determinant of evolutionarily selected native contact topology.

  8. Global low-frequency motions in protein allostery: CAP as a model system.

    Townsend, Philip D; Rodgers, Thomas L; Pohl, Ehmke; Wilson, Mark R; McLeish, Tom C B; Cann, Martin J

    2015-06-01

    Allostery is a fundamental process by which ligand binding to a protein alters its activity at a distant site. There is considerable evidence that allosteric cooperativity can be communicated by the modulation of protein dynamics without conformational change. The Catabolite Activator Protein (CAP) of Escherichia coli is an important experimental exemplar for entropically driven allostery. Here we discuss recent experimentally supported theoretical analysis that highlights the role of global low-frequency dynamics in allostery in CAP and identify how allostery arises as a natural consequence of changes in global low-frequency protein fluctuations on ligand binding.

  9. Global Rating Scales and Motion Analysis Are Valid Proficiency Metrics in Virtual and Benchtop Knee Arthroscopy Simulators.

    Chang, Justues; Banaszek, Daniel C; Gambrel, Jason; Bardana, Davide

    2016-04-01

    Work-hour restrictions and fatigue management strategies in surgical training programs continue to evolve in an effort to improve the learning environment and promote safer patient care. In response, training programs must reevaluate how various teaching modalities such as simulation can augment the development of surgical competence in trainees. For surgical simulators to be most useful, it is important to determine whether surgical proficiency can be reliably differentiated using them. To our knowledge, performance on both virtual and benchtop arthroscopy simulators has not been concurrently assessed in the same subjects. (1) Do global rating scales and procedure time differentiate arthroscopic expertise in virtual and benchtop knee models? (2) Can commercially available built-in motion analysis metrics differentiate arthroscopic expertise? (3) How well are performance measures on virtual and benchtop simulators correlated? (4) Are these metrics sensitive enough to differentiate by year of training? A cross-sectional study of 19 subjects (four medical students, 12 residents, and three staff) were recruited and divided into 11 novice arthroscopists (student to Postgraduate Year [PGY] 3) and eight proficient arthroscopists (PGY 4 to staff) who completed a diagnostic arthroscopy and loose-body retrieval in both virtual and benchtop knee models. Global rating scales (GRS), procedure times, and motion analysis metrics were used to evaluate performance. The proficient group scored higher on virtual (14 ± 6 [95% confidence interval {CI}, 10-18] versus 36 ± 5 [95% CI, 32-40], p virtual scope (579 ±169 [95% CI, 466-692] versus 358 ± 178 [95% CI, 210-507] seconds, p = 0.02) and benchtop knee scope + probe (480 ± 160 [95% CI, 373-588] versus 277 ± 64 [95% CI, 224-330] seconds, p = 0.002). The built-in motion analysis metrics also distinguished novices from proficient arthroscopists using the self-generated virtual loose body retrieval task scores (4 ± 1 [95% CI, 3

  10. A Global Integration: Internationalizing a Public Speaking Course

    Lyons, Florence A.

    2017-01-01

    Institutions of higher education around the world have responded to the challenge of globalization by internationalizing their curricula. Incorporating elements of cross-cultural examination to a freshman Fundamentals of Public Speaking class proved to be an important first step toward globalization for this speech professor. In the class,…

  11. Potential of mechanical metamaterials to induce their own global rotational motion

    Dudek, K. K.; Wojciechowski, K. W.; Dudek, M. R.; Gatt, R.; Mizzi, L.; Grima, J. N.

    2018-05-01

    The potential of several classes of mechanical metamaterials to induce their own overall rotational motion through the individual rotation of their subunits is examined. Using a theoretical approach, we confirm that for various rotating rigid unit systems, if by design the sum of angular momentum of subunits rotating in different directions is made to be unequal, then the system will experience an overall rotation, the extent of which may be controlled through careful choice of the geometric parameters defining these systems. This phenomenon of self-induced rotation is also confirmed experimentally. Furthermore, we discuss how these systems can be designed in a special way so as to permit extended rotations which allows them to overcome geometric lockage and the relevance of this concept in applications ranging from satellites to spacecraft and telescopes employed in space.

  12. Global Existence of Classical Solutions to the Equations of Motion for Materials with Fading Memory.

    1984-02-01

    influence function , history value problems, classical solutions, global existence, decay. Work Unit Number 1 - Applied Analysis Sponsored by the United...introduce an " influence function " h, intended to JIN. characterize the rate at which memory fades, and construct an LP-type space of admissible...histories using the influence function as a weight. Here we use the term influence function to mean a positive, nonincreasing, real-valued function h e L (0

  13. The motion of the rigid body in viscous fluid including collisions. Global solvability result

    Chemetov, N.; Nečasová, Šárka

    2017-01-01

    Roč. 34, April (2017), s. 416-445 ISSN 1468-1218 R&D Projects: GA ČR GA16-03230S Institutional support: RVO:67985840 Keywords : rigid body * global weak solution * collisions in finite time Subject RIV: BA - General Mathematics OBOR OECD: Pure mathematics Impact factor: 1.659, year: 2016 http://www.sciencedirect.com/science/article/pii/S1468121816301146

  14. PET motion correction in context of integrated PET/MR: Current techniques, limitations, and future projections.

    Gillman, Ashley; Smith, Jye; Thomas, Paul; Rose, Stephen; Dowson, Nicholas

    2017-12-01

    Patient motion is an important consideration in modern PET image reconstruction. Advances in PET technology mean motion has an increasingly important influence on resulting image quality. Motion-induced artifacts can have adverse effects on clinical outcomes, including missed diagnoses and oversized radiotherapy treatment volumes. This review aims to summarize the wide variety of motion correction techniques available in PET and combined PET/CT and PET/MR, with a focus on the latter. A general framework for the motion correction of PET images is presented, consisting of acquisition, modeling, and correction stages. Methods for measuring, modeling, and correcting motion and associated artifacts, both in literature and commercially available, are presented, and their relative merits are contrasted. Identified limitations of current methods include modeling of aperiodic and/or unpredictable motion, attaining adequate temporal resolution for motion correction in dynamic kinetic modeling acquisitions, and maintaining availability of the MR in PET/MR scans for diagnostic acquisitions. Finally, avenues for future investigation are discussed, with a focus on improvements that could improve PET image quality, and that are practical in the clinical environment. © 2017 American Association of Physicists in Medicine.

  15. Variational Symplectic Integrator for Long-Time Simulations of the Guiding-Center Motion of Charged Particles in General Magnetic Fields

    Qin Hong; Guan Xiaoyin

    2008-01-01

    A variational symplectic integrator for the guiding-center motion of charged particles in general magnetic fields is developed for long-time simulation studies of magnetized plasmas. Instead of discretizing the differential equations of the guiding-center motion, the action of the guiding-center motion is discretized and minimized to obtain the iteration rules for advancing the dynamics. The variational symplectic integrator conserves exactly a discrete Lagrangian symplectic structure, and has better numerical properties over long integration time, compared with standard integrators, such as the standard and variable time-step fourth order Runge-Kutta methods

  16. Variational Symplectic Integrator for Long-Time Simulations of the Guiding-Center Motion of Charged Particles in General Magnetic Fields

    Qin, H.; Guan, X.

    2008-01-01

    A variational symplectic integrator for the guiding-center motion of charged particles in general magnetic fields is developed for long-time simulation studies of magnetized plasmas. Instead of discretizing the differential equations of the guiding-center motion, the action of the guiding-center motion is discretized and minimized to obtain the iteration rules for advancing the dynamics. The variational symplectic integrator conserves exactly a discrete Lagrangian symplectic structure, and has better numerical properties over long integration time, compared with standard integrators, such as the standard and variable time-step fourth order Runge-Kutta methods.

  17. A motion-based integer ambiguity resolution method for attitude determination using the global positioning system (GPS)

    Wang, Bo; Deng, Zhihong; Wang, Shunting; Fu, Mengyin

    2010-01-01

    Loss of the satellite signal and noise disturbance will cause cycle slips to occur in the carrier phase observation of the attitude determination system using the global positioning system (GPS), especially in the dynamic situation. Therefore, in order to reject the error by cycle slips, the integer ambiguity should be re-computed. A motion model-based Kalman predictor is used for the ambiguity re-computation in dynamic applications. This method utilizes the correct observation of the last step to predict the current ambiguities. With the baseline length as a constraint to reject invalid values, we can solve the current integer ambiguity and the attitude angles, by substituting the obtained ambiguities into the constrained LAMBDA method. Experimental results demonstrate that the proposed method is more efficient in the dynamic situation, which takes less time to obtain new fixed ambiguities with a higher mean success rate

  18. Global rotational motion and displacement estimation of digital image stabilization based on the oblique vectors matching algorithm

    Yu, Fei; Hui, Mei; Zhao, Yue-jin

    2009-08-01

    The image block matching algorithm based on motion vectors of correlative pixels in oblique direction is presented for digital image stabilization. The digital image stabilization is a new generation of image stabilization technique which can obtains the information of relative motion among frames of dynamic image sequences by the method of digital image processing. In this method the matching parameters are calculated from the vectors projected in the oblique direction. The matching parameters based on the vectors contain the information of vectors in transverse and vertical direction in the image blocks at the same time. So the better matching information can be obtained after making correlative operation in the oblique direction. And an iterative weighted least square method is used to eliminate the error of block matching. The weights are related with the pixels' rotational angle. The center of rotation and the global emotion estimation of the shaking image can be obtained by the weighted least square from the estimation of each block chosen evenly from the image. Then, the shaking image can be stabilized with the center of rotation and the global emotion estimation. Also, the algorithm can run at real time by the method of simulated annealing in searching method of block matching. An image processing system based on DSP was used to exam this algorithm. The core processor in the DSP system is TMS320C6416 of TI, and the CCD camera with definition of 720×576 pixels was chosen as the input video signal. Experimental results show that the algorithm can be performed at the real time processing system and have an accurate matching precision.

  19. Integrated fMRI Preprocessing Framework Using Extended Kalman Filter for Estimation of Slice-Wise Motion

    Basile Pinsard

    2018-04-01

    Full Text Available Functional MRI acquisition is sensitive to subjects' motion that cannot be fully constrained. Therefore, signal corrections have to be applied a posteriori in order to mitigate the complex interactions between changing tissue localization and magnetic fields, gradients and readouts. To circumvent current preprocessing strategies limitations, we developed an integrated method that correct motion and spatial low-frequency intensity fluctuations at the level of each slice in order to better fit the acquisition processes. The registration of single or multiple simultaneously acquired slices is achieved online by an Iterated Extended Kalman Filter, favoring the robust estimation of continuous motion, while an intensity bias field is non-parametrically fitted. The proposed extraction of gray-matter BOLD activity from the acquisition space to an anatomical group template space, taking into account distortions, better preserves fine-scale patterns of activity. Importantly, the proposed unified framework generalizes to high-resolution multi-slice techniques. When tested on simulated and real data the latter shows a reduction of motion explained variance and signal variability when compared to the conventional preprocessing approach. These improvements provide more stable patterns of activity, facilitating investigation of cerebral information representation in healthy and/or clinical populations where motion is known to impact fine-scale data.

  20. Integrals of periodic motion and periodic solutions for classical equations of relativistic string with masses at ends. I. Integrals of periodic motion

    Barbashov, B.M.

    1996-01-01

    Boundary equations for the relativistic string with masses at ends are formulated in terms of geometrical invariants of world trajectories of masses at the string ends. In the three-dimensional Minkowski space E 2 1 , there are two invariants of that sort, the curvature K and torsion κ. Curvatures of trajectories of the string ends with masses are always constant, K i =γ/m i (i=1,2), whereas torsions κ i obey a system of differential equations with deviating arguments. For these equations with periodic κ i (τ+nl)=κ(τ), constants of motion are obtained (part 1) and exact solutions are presented (part 2) for periods l and 2l where l is the string length in the plane of parameters τ and σ(σ 1 =0, σ 2 =l). 7 refs

  1. Integrating global energy and climate governance: The changing role of the International Energy Agency

    Heubaum, Harald; Biermann, Frank

    2015-01-01

    Despite the long-recognized interlinkages between global energy consumption and climate change, there has historically been only limited policy interaction, let alone integration, between the two fields. This compartmentalization is mirrored in scholarship, where much research has focused on the fragmentation of, respectively, global energy and global climate governance, but only little has been said about how these fields might be integrated. Our analysis of the International Energy Agency’s (IEA) changing activities in recent years shows that governance integration – both within global energy governance and between global energy and climate governance – is now happening. The IEA has broadened its portfolio to embrace the full spectrum of energy issues, including renewable energy and climate change; it has built and is expanding key partnerships with both the UN climate convention and the International Renewable Energy Agency (IRENA); and it has become an authoritative advocate for the inter-related goals of a low-carbon transition and climate change mitigation. We show that these developments are not the result of a top-down plan, but have rather emerged through the Agency’s various efforts to pursue its energy-centric mandate in a fast-changing global policy environment. - Highlights: • Assesses integration between global energy and global climate governance. • Analyzes organizational change in the IEA and its impact on governance integration. • Discusses recent activities and advocacy by the IEA in relation to climate change.

  2. B2B Integration in Global Supply Chains

    Schubert, Petra; Legner, Christine

    2011-01-01

    The competitiveness of businesses is increasingly dependent on their electronic networks with customers, suppliers, and partners. While the strategic and operational impact of external integration and IOS adoption has been extensively studied, much less attention has been paid to the organizational...... and technical design of electronic relationships. The objective of our longitudinal research project is the development of a framework for understanding and explaining B2B integration. Drawing on existing literature and empirical cases we present a reference model (a classification scheme for B2B Integration...

  3. Global Citizenship and the Importance of Education in a Globally Integrated World

    Smith, William C.; Fraser, Pablo; Chykina, Volha; Ikoma, Sakiko; Levitan, Joseph; Liu, Jing; Mahfouz, Julia

    2017-01-01

    As national borders dissipate and technology allows different cultures and nationalities to communicate on a regular basis, more individuals are self-identifying as a global citizen. Using Social Network Analysis and multi-level modelling, this study explores factors associated with global citizen affinity and finds that education plays an…

  4. Integrating factors and conservation theorems for Hamilton's canonical equations of motion of variable mass nonholonomic nonconservative dynamical systems

    李仁杰; 乔永芬; 刘洋

    2002-01-01

    We present a general approach to the construction of conservation laws for variable mass nonholonomic noncon-servative systems. First, we give the definition of integrating factors, and we study in detail the necessary conditionsfor the existence of the conserved quantities. Then, we establish the conservation theorem and its inverse theorem forHamilton's canonical equations of motion of variable mass nonholonomic nonconservative dynamical systems. Finally,we give an example to illustrate the application of the results.

  5. Integrating factors and conservation theorems for Hamilton‘s canonical equations of motion of variable mass nonholonmic nonconservative dynamical systems

    李仁杰; 刘洋; 等

    2002-01-01

    We present a general approach to the construction of conservation laws for variable mass noholonmic nonconservative systems.First,we give the definition of integrating factors,and we study in detail the necessary conditions for the existence of the conserved quantities,Then,we establish the conservatioin theorem and its inverse theorem for Hamilton's canonical equations of motion of variable mass nonholonomic nonocnservative dynamical systems.Finally,we give an example to illustrate the application of the results.

  6. Relative motions of the Australian, Pacific and Antarctic plates estimated by the Global Positioning System

    Larson, Kristine M.; Freymueller, Jeff

    1995-01-01

    Global Positioning System (GPS) measurements spanning approximately 3 years have been used to determine velocities for 7 sites on the Australian, Pacific and Antarctic plates. The site velocities agree with both plate model predictions and other space geodetic techniques. We find no evidence for internal deformation of the interior of the Australian plate. Wellington, New Zealand, located in the Australian-Pacific plate boundary zone, moves 20 +/- 5 mm/yr west-southwest relative to the Australian plate. Its velocity lies midway between the predicted velocities of the two plates. Relative Euler vectors for the Australia-Antarctica and Pacific-Antarctica plates agree within one standard deviation with the NUVEL-1A predictions.

  7. Integrating forest products with ecosystem services: a global perspective

    Robert L. Deal; Rachel. White

    2012-01-01

    Around the world forests provide a broad range of vital ecosystem services. Sustainable forest management and forest products play an important role in global carbon management, but one of the major forestry concerns worldwide is reducing the loss of forestland from development. Currently, deforestation accounts for approximately 20% of total greenhouse gas emissions....

  8. Holocaust Education: Global Forces Shaping Curricula Integration and Implementation

    Davis, Bryan L.; Rubinstein-Avila, Eliane

    2013-01-01

    The article provides a critical review of the global scholarship on Holocaust education (HE). Despite the growing body of work on this topic, a search through major academic databases by the authors revealed that no such review of the research literature has been published as of yet. The review focuses on three main themes across the research…

  9. Power Take-Off with Integrated Resonator for Energy Extraction from Linear Motions

    2014-01-01

    The invention relates to a magnetic gear for converting linear motion into rotational motion and vice versa. The present invention converts slow linear irregular oscillating motion of wave energy devices into torque on a high speed shaft for powering a generator while making the wave energy device...... of sea or ocean waves into useful energy, such as electricity. The invention relates to the control and operation of a magnetic gear based motor/generator system. The invention provides a high force density electric powered linear actuator....... resonate with the waves. The invention relates to the field of energy-harvesting from energy sources, where the energy-harvesting requires the extraction of energy from slow and often irregular reciprocating motion of bodies. The present invention relates to a wave power apparatus for converting power...

  10. Global pharmaceutical regulation: the challenge of integration for developing states.

    Pezzola, Anthony; Sweet, Cassandra M

    2016-12-20

    This paper has set out to map the state of pharmaceutical regulation in the developing world through the construction of cross-national indices drawing from World Health Organization data. The last two decades have been characterized by deep changes for the pharmaceutical sector, including the complete transformation of intellectual property systems at the behest of the World Trade Organization and the consolidation of global active ingredient suppliers in China and India. Although the rules for ownership of medicine have been set and globally implemented, we know surprisingly little about how the standards for market entrance and regulation of pharmaceutical products have changed at the national level. How standardized are national pharmaceutical market systems? Do we find homogeneity or variation across the developing world? Are their patterns for understanding why some countries have moved closer to one global norm for pharmaceutical regulation and others have developed hybrid models for oversight of this sector? Access to medicine is a core tool in public health. This paper gauges the levels of standards in public and private generics markets for developing countries building on national-level pharmaceutical market surveys for 78 countries to offer three indicators of market oversight: State Regulatory Infrastructure, Monitoring the Private Market and Public Quality Control. Identifying the different variables that affect a state's institutional capacity and current standard level offers new insights to the state of pharmaceuticals in the developing world. It is notable that there are very few (none at the time of this paper) studies that map out the new global terrain for pharmaceutical regulation in the post-TRIPS context. This paper uses item response theory to develop original indicators of pharmaceutical regulation. We find remarkable resistance to the implementation of global pharmaceutical norms for quality standards in developing states and in

  11. Ground-Based Global Positioning System (GPS) Meteorology Integrated Precipitable Water Vapor (IPW)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Ground-Based Global Positioning System (GPS) Meteorology Integrated Precipitable Water Vapor (IPW) data set measures atmospheric water vapor using ground-based...

  12. Temporal dynamics of 2D motion integration for ocular following in macaque monkeys.

    Barthélemy, Fréderic V; Fleuriet, Jérome; Masson, Guillaume S

    2010-03-01

    Several recent studies have shown that extracting pattern motion direction is a dynamical process where edge motion is first extracted and pattern-related information is encoded with a small time lag by MT neurons. A similar dynamics was found for human reflexive or voluntary tracking. Here, we bring an essential, but still missing, piece of information by documenting macaque ocular following responses to gratings, unikinetic plaids, and barber-poles. We found that ocular tracking was always initiated first in the grating motion direction with ultra-short latencies (approximately 55 ms). A second component was driven only 10-15 ms later, rotating tracking toward pattern motion direction. At the end the open-loop period, tracking direction was aligned with pattern motion direction (plaids) or the average of the line-ending motion directions (barber-poles). We characterized the dependency on contrast of each component. Both timing and direction of ocular following were quantitatively very consistent with the dynamics of neuronal responses reported by others. Overall, we found a remarkable consistency between neuronal dynamics and monkey behavior, advocating for a direct link between the neuronal solution of the aperture problem and primate perception and action.

  13. INTEGRATION OF TRADE AND DISINTEGRATION OF PRODUCTION IN THE GLOBAL ECONOMY

    Robert Feenstra

    2003-01-01

    The last few decades have seen a spectacular integration of the global economy through trade. The rising integration of world markets has brought with it a disintegration of the production process, however, in which manufacturing or services activities done abroad are combined with those performed at home. The author compares several different measures of foreign outsourcing and argues that they have all increased since the 1970s. He also considers the implications of globalization for employ...

  14. MO-FG-BRA-02: A Feasibility Study of Integrating Breathing Audio Signal with Surface Surrogates for Respiratory Motion Management

    Lei, Y; Zhu, X; Zheng, D; Li, S; Ma, R; Zhang, M; Fan, Q; Wang, X; Verma, V; Zhou, S [University of Nebraska Medical Center, Omaha, NE (United States); Tang, X [Memorial Sloan Kettering Cancer Center, West Harrison, NY (United States)

    2016-06-15

    Purpose: Tracking the surrogate placed on patient skin surface sometimes leads to problematic signals for certain patients, such as shallow breathers. This in turn impairs the 4D CT image quality and dosimetric accuracy. In this pilot study, we explored the feasibility of monitoring human breathing motion by integrating breathing sound signal with surface surrogates. Methods: The breathing sound signals were acquired though a microphone attached adjacently to volunteer’s nostrils, and breathing curve were analyzed using a low pass filter. Simultaneously, the Real-time Position Management™ (RPM) system from Varian were employed on a volunteer to monitor respiratory motion including both shallow and deep breath modes. The similar experiment was performed by using Calypso system, and three beacons taped on volunteer abdominal region to capture breath motion. The period of each breathing curves were calculated with autocorrelation functions. The coherence and consistency between breathing signals using different acquisition methods were examined. Results: Clear breathing patterns were revealed by the sound signal which was coherent with the signal obtained from both the RPM system and Calypso system. For shallow breathing, the periods of breathing cycle were 3.00±0.19 sec (sound) and 3.00±0.21 sec (RPM); For deep breathing, the periods were 3.49± 0.11 sec (sound) and 3.49±0.12 sec (RPM). Compared with 4.54±0.66 sec period recorded by the calypso system, the sound measured 4.64±0.54 sec. The additional signal from sound could be supplement to the surface monitoring, and provide new parameters to model the hysteresis lung motion. Conclusion: Our preliminary study shows that the breathing sound signal can provide a comparable way as the RPM system to evaluate the respiratory motion. It’s instantaneous and robust characteristics facilitate it possibly to be a either independently or as auxiliary methods to manage respiratory motion in radiotherapy.

  15. MO-FG-BRA-02: A Feasibility Study of Integrating Breathing Audio Signal with Surface Surrogates for Respiratory Motion Management

    Lei, Y; Zhu, X; Zheng, D; Li, S; Ma, R; Zhang, M; Fan, Q; Wang, X; Verma, V; Zhou, S; Tang, X

    2016-01-01

    Purpose: Tracking the surrogate placed on patient skin surface sometimes leads to problematic signals for certain patients, such as shallow breathers. This in turn impairs the 4D CT image quality and dosimetric accuracy. In this pilot study, we explored the feasibility of monitoring human breathing motion by integrating breathing sound signal with surface surrogates. Methods: The breathing sound signals were acquired though a microphone attached adjacently to volunteer’s nostrils, and breathing curve were analyzed using a low pass filter. Simultaneously, the Real-time Position Management™ (RPM) system from Varian were employed on a volunteer to monitor respiratory motion including both shallow and deep breath modes. The similar experiment was performed by using Calypso system, and three beacons taped on volunteer abdominal region to capture breath motion. The period of each breathing curves were calculated with autocorrelation functions. The coherence and consistency between breathing signals using different acquisition methods were examined. Results: Clear breathing patterns were revealed by the sound signal which was coherent with the signal obtained from both the RPM system and Calypso system. For shallow breathing, the periods of breathing cycle were 3.00±0.19 sec (sound) and 3.00±0.21 sec (RPM); For deep breathing, the periods were 3.49± 0.11 sec (sound) and 3.49±0.12 sec (RPM). Compared with 4.54±0.66 sec period recorded by the calypso system, the sound measured 4.64±0.54 sec. The additional signal from sound could be supplement to the surface monitoring, and provide new parameters to model the hysteresis lung motion. Conclusion: Our preliminary study shows that the breathing sound signal can provide a comparable way as the RPM system to evaluate the respiratory motion. It’s instantaneous and robust characteristics facilitate it possibly to be a either independently or as auxiliary methods to manage respiratory motion in radiotherapy.

  16. Integrating global socio-economic influences into a regional land use change model for China

    Xu, Xia; Gao, Qiong; Peng, Changhui; Cui, Xuefeng; Liu, Yinghui; Jiang, Li

    2014-03-01

    With rapid economic development and urbanization, land use in China has experienced huge changes in recent years; and this will probably continue in the future. Land use problems in China are urgent and need further study. Rapid land-use change and economic development make China an ideal region for integrated land use change studies, particularly the examination of multiple factors and global-regional interactions in the context of global economic integration. This paper presents an integrated modeling approach to examine the impact of global socio-economic processes on land use changes at a regional scale. We develop an integrated model system by coupling a simple global socio-economic model (GLOBFOOD) and regional spatial allocation model (CLUE). The model system is illustrated with an application to land use in China. For a given climate change, population growth, and various socio-economic situations, a global socio-economic model simulates the impact of global market and economy on land use, and quantifies changes of different land use types. The land use spatial distribution model decides the type of land use most appropriate in each spatial grid by employing a weighted suitability index, derived from expert knowledge about the ecosystem state and site conditions. A series of model simulations will be conducted and analyzed to demonstrate the ability of the integrated model to link global socioeconomic factors with regional land use changes in China. The results allow an exploration of the future dynamics of land use and landscapes in China.

  17. Global Format for Conservative Time Integration in Nonlinear Dynamics

    Krenk, Steen

    2014-01-01

    The widely used classic collocation-based time integration procedures like Newmark, Generalized-alpha etc. generally work well within a framework of linear problems, but typically may encounter problems, when used in connection with essentially nonlinear structures. These problems are overcome....... In the present paper a conservative time integration algorithm is developed in a format using only the internal forces and the associated tangent stiffness at the specific time integration points. Thus, the procedure is computationally very similar to a collocation method, consisting of a series of nonlinear...... equivalent static load steps, easily implemented in existing computer codes. The paper considers two aspects: representation of nonlinear internal forces in a form that implies energy conservation, and the option of an algorithmic damping with the purpose of extracting energy from undesirable high...

  18. Constraint-based query distribution framework for an integrated global schema

    Malik, Ahmad Kamran; Qadir, Muhammad Abdul; Iftikhar, Nadeem

    2009-01-01

    and replicated data sources. The provided system is all XML-based which poses query in XML form, transforms, and integrates local results in an XML document. Contributions include the use of constraints in our existing global schema which help in source selection and query optimization, and a global query...

  19. Global sensitivity analysis of DRAINMOD-FOREST, an integrated forest ecosystem model

    Shiying Tian; Mohamed A. Youssef; Devendra M. Amatya; Eric D. Vance

    2014-01-01

    Global sensitivity analysis is a useful tool to understand process-based ecosystem models by identifying key parameters and processes controlling model predictions. This study reported a comprehensive global sensitivity analysis for DRAINMOD-FOREST, an integrated model for simulating water, carbon (C), and nitrogen (N) cycles and plant growth in lowland forests. The...

  20. Integrating Global Learning into a Psychology Course Using an Online Platform

    Forden, Carie L.; Carrillo, Amy M.

    2014-01-01

    There is a demand for the integration of global learning/diversity across the curriculum. A series of cross-cultural assignments was created to facilitate global learning in two social psychology classes, one in Egypt, and one in the USA. In these assignments, students collected data and applied course concepts to real-life problems, then…

  1. Global sourcing - performance and integration : reflections on performance, implications from cross-functional and external integration

    Horn, Philipp

    2013-01-01

    Despite the fact that firms and individuals have been sourcing on a global basis since ancient times, global sourcing as a topic has received considerable attention from managers and scholars in recent years. Global business has been reported to be growing considerably during the last decades and

  2. 75 FR 20388 - International Business Machines Corporation, Global Technology Services Business Unit, Integrated...

    2010-04-19

    ... Machines Corporation, Global Technology Services Business Unit, Integrated Technology Services, Cost and... Technology Services Business Unit, Integrated Technology Services, Cost and Expense Team working from various... Technology Services Business Unit. The company reports that workers leased from Datrose, Inc., were employed...

  3. Exploring Connections Between Global Integration and Political Mobilization

    Jackie Smith

    2015-08-01

    Full Text Available With the end of the Cold War, military security issues declined on the international agenda as environmental, economic, and social issues rose. As superpower con?ict faded from the international agenda, space was created for new attempts at multilateral problem-solving. How have these changes a?ected the prospects for transnational organizing? Using data from the Yearbook of International Associations this paper explores changes in the size, issue focus, geographic makeup, and organizational structure of the population of transnational social movement organizations (TSMOs in recent decades. While not the only form of transna-tional cooperation, these formal organizations provide important infrastructures for sustained transnational political work. Key ?ndings are that while the transnational social movement sector has continued to grow since the mid-20th century, its rate of growth has slowed in the 1990s. Also, human rights and environment predominate on TSMO issue-agendas, but during the 1990s more groups emphasized economic issues and adopted multi-issue organizing frames over single-issue focuses. Newer groups were more likely to be organized regionally, that is within the global North or South, which may re?ect e?orts to develop structures to better connect local settings with global networks.

  4. A Global MBA for Tomorrow's Global Business Leaders: Integrating Best Practice with Boston's Locational Advantage

    Delaunay, Christian J.; Blodgett, Mark S.

    2005-01-01

    Traditional IB programs have received mixed reviews from the corporate world. With this in mind, the Suffolk GMBA was benchmarked against the leading international business programs. The Suffolk GMBA was designed to be different and to ascertain the global environment in which business operates. A unique feature of the GMBA curriculum detailed in…

  5. Accelerometer Based Motional Feedback Integrated in a 2 3/4" Loudspeaker

    Bjerregaard, Ruben; Madsen, Anders Normann; Schneider, Henrik

    2016-01-01

    It is a well known fact that loudspeakers produce distortion when they are driven into large diaphragm displacements. Various methods exist to reduce distortion using forward compensation and feedback methods. Acceleration based motional feedback is one of these methods and was already thoroughly...

  6. Contribution of vertical land motions to coastal sea level variations: a global synthesis of multisatellite altimetry, tide gauge and GPS measurements

    Pfeffer, Julia; Allemand, Pascal

    2016-04-01

    Coastal sea level variations result from a complex mix of climatic, oceanic and geodynamical processes driven by natural and anthropogenic constraints. Combining data from multiple sources is one solution to identify particular processes and progress towards a better understanding of the sea level variations and the assessment of their impacts at coast. Here, we present a global database merging multisatellite altimetry with tide gauges and Global Positioning System (GPS) measurements. Vertical land motions and sea level variations are estimated simultaneously for a network of 886 ground stations with median errors lower than 1 mm/yr. The contribution of vertical land motions to relative sea level variations is explored to better understand the natural hazards associated with sea level rise in coastal areas. Worldwide, vertical land motions dominate 30 % of observed coastal trends. The role of the crust is highly heterogeneous: it can amplify, restrict or counter the effects of climate-induced sea level change. A set of 182 potential vulnerable localities are identified by large coastal subsidence which increases by several times the effects of sea level rise. Though regional behaviours exist, principally caused by GIA (Glacial Isostatic Adjustment), the local variability in vertical land motion prevails. An accurate determination of the vertical motions observed at the coast is fundamental to understand the local processes which contribute to sea level rise, to appraise its impacts on coastal populations and make future predictions.

  7. Integrated assessment of the global warming problem: A decision-analytical approach

    Van Lenthe, J.; Hendrickx, L.; Vlek, C.A.J.

    1994-12-01

    The multi-disciplinary character of the global warming problem asks for an integrated assessment approach for ordering and combining the various physical, ecological, economical, and sociological results. The Netherlands initiated their own National Research Program (NRP) on Global Air Pollution and Climate Change (NRP). The first phase (NRP-1) identified the integration theme as one of five central research themes. The second phase (NRP-2) shows a growing concern for integrated assessment issues. The current two-year research project 'Characterizing the risks: a comparative analysis of the risks of global warming and of relevant policy options, which started in September 1993, comes under the integrated assessment part of the Dutch NRP. The first part of the interim report describes the search for an integrated assessment methodology. It starts with emphasizing the need for integrated assessment at a relatively high level of aggregation and from a policy point of view. The conclusion will be that a decision-analytical approach might fit the purpose of a policy-oriented integrated modeling of the global warming problem. The discussion proceeds with an account on decision analysis and its explicit incorporation and analysis of uncertainty. Then influence diagrams, a relatively recent development in decision analysis, are introduced as a useful decision-analytical approach for integrated assessment. Finally, a software environment for creating and analyzing complex influence diagram models is discussed. The second part of the interim report provides a first, provisional integrated modeling of the global warming problem, emphasizing on the illustration of the decision-analytical approach. Major problem elements are identified and an initial problem structure is developed. The problem structure is described in terms of hierarchical influence diagrams. At some places the qualitative structure is filled with quantitative data

  8. A Global Rapid Integrated Monitoring System for Water Cycle and Water Resource Assessment (Global-RIMS)

    Roads, John; Voeroesmarty, Charles

    2005-01-01

    The main focus of our work was to solidify underlying data sets, the data processing tools and the modeling environment needed to perform a series of long-term global and regional hydrological simulations leading eventually to routine hydrometeorological predictions. A water and energy budget synthesis was developed for the Mississippi River Basin (Roads et al. 2003), in order to understand better what kinds of errors exist in current hydrometeorological data sets. This study is now being extended globally with a larger number of observations and model based data sets under the new NASA NEWS program. A global comparison of a number of precipitation data sets was subsequently carried out (Fekete et al. 2004) in which it was further shown that reanalysis precipitation has substantial problems, which subsequently led us to the development of a precipitation assimilation effort (Nunes and Roads 2005). We believe that with current levels of model skill in predicting precipitation that precipitation assimilation is necessary to get the appropriate land surface forcing.

  9. Global Navigation Satellite Systems (GNSS: The Utmost Interdisciplinary Integrator

    Bernd Eissfeller

    2015-08-01

    Full Text Available Currently four global satellite navigation systems are under modernization and development: The US American GPS III, the Russian GLONASS, the European Galileo and Chinese BeiDou systems. In the paper the interdisciplinary contributions of different scientific areas to GNSS are assessed. It is outlined that GNSS is not only a technical system but also a basic element of mobile computing high-tech market. At the same time a GNSS has the role of a force enabler in security related applications. Technology, market and security policies are interdependent and are sometimes in a relationship of tension. The goal of the paper is to describe the overall systemics of GNSS from a holistic point of view. The paper also addresses the human factor side of GNSS. The requirements on human resources in GNSS are at least two-fold: On the one hand very specialized engineers are needed; on the other hand the generalists are necessary who are able to understand the system aspects. Decision makers in institutions and industry need special knowledge in technologies, economics and political strategies. Is the current university system able to educate and prepare such generalists? Are specialized master courses for GNSS needed? Are external training courses necessary?

  10. Collective versus single-particle motion in quantum many-body systems from the perspective of an integrable model

    Haemmerling, Jens; Gutkin, Boris; Guhr, Thomas, E-mail: jens.haemmerling@uni-due.d [Universitaet Duisburg-Essen, Lotharstrasse 1, 47048 Duisburg (Germany)

    2010-07-02

    We study the emergence of collective dynamics in the integrable Hamiltonian system of two finite ensembles of coupled harmonic oscillators. After identification of a collective degree of freedom, the Hamiltonian is mapped onto a model of Caldeira-Leggett type, where the collective coordinate is coupled to an internal bath of phonons. In contrast to the usual Caldeira-Leggett model, the bath in the present case is part of the system. We derive an equation of motion for the collective coordinate which takes the form of a damped harmonic oscillator. We show that the distribution of quantum transition strengths induced by the collective mode is determined by its classical dynamics.

  11. Collective versus single-particle motion in quantum many-body systems from the perspective of an integrable model

    Haemmerling, Jens; Gutkin, Boris; Guhr, Thomas

    2010-01-01

    We study the emergence of collective dynamics in the integrable Hamiltonian system of two finite ensembles of coupled harmonic oscillators. After identification of a collective degree of freedom, the Hamiltonian is mapped onto a model of Caldeira-Leggett type, where the collective coordinate is coupled to an internal bath of phonons. In contrast to the usual Caldeira-Leggett model, the bath in the present case is part of the system. We derive an equation of motion for the collective coordinate which takes the form of a damped harmonic oscillator. We show that the distribution of quantum transition strengths induced by the collective mode is determined by its classical dynamics.

  12. Real-Time Correction By Optical Tracking with Integrated Geometric Distortion Correction for Reducing Motion Artifacts in fMRI

    Rotenberg, David J.

    Artifacts caused by head motion are a substantial source of error in fMRI that limits its use in neuroscience research and clinical settings. Real-time scan-plane correction by optical tracking has been shown to correct slice misalignment and non-linear spin-history artifacts, however residual artifacts due to dynamic magnetic field non-uniformity may remain in the data. A recently developed correction technique, PLACE, can correct for absolute geometric distortion using the complex image data from two EPI images, with slightly shifted k-space trajectories. We present a correction approach that integrates PLACE into a real-time scan-plane update system by optical tracking, applied to a tissue-equivalent phantom undergoing complex motion and an fMRI finger tapping experiment with overt head motion to induce dynamic field non-uniformity. Experiments suggest that including volume by volume geometric distortion correction by PLACE can suppress dynamic geometric distortion artifacts in a phantom and in vivo and provide more robust activation maps.

  13. Earth science information: Planning for the integration and use of global change information

    Lousma, Jack R.

    1992-01-01

    Activities and accomplishments of the first six months of the Consortium for International Earth Science Information Network (CIESIN's) 1992 technical program have focused on four main missions: (1) the development and implementation of plans for initiation of the Socioeconomic Data and Applications Center (SEDAC) as part of the EOSDIS Program; (2) the pursuit and development of a broad-based global change information cooperative by providing systems analysis and integration between natural science and social science data bases held by numerous federal agencies and other sources; (3) the fostering of scientific research into the human dimensions of global change and providing integration between natural science and social science data and information; and (4) the serving of CIESIN as a gateway for global change data and information distribution through development of the Global Change Research Information Office and other comprehensive knowledge sharing systems.

  14. Integration and global analysis of isothermal titration calorimetry data for studying macromolecular interactions.

    Brautigam, Chad A; Zhao, Huaying; Vargas, Carolyn; Keller, Sandro; Schuck, Peter

    2016-05-01

    Isothermal titration calorimetry (ITC) is a powerful and widely used method to measure the energetics of macromolecular interactions by recording a thermogram of differential heating power during a titration. However, traditional ITC analysis is limited by stochastic thermogram noise and by the limited information content of a single titration experiment. Here we present a protocol for bias-free thermogram integration based on automated shape analysis of the injection peaks, followed by combination of isotherms from different calorimetric titration experiments into a global analysis, statistical analysis of binding parameters and graphical presentation of the results. This is performed using the integrated public-domain software packages NITPIC, SEDPHAT and GUSSI. The recently developed low-noise thermogram integration approach and global analysis allow for more precise parameter estimates and more reliable quantification of multisite and multicomponent cooperative and competitive interactions. Titration experiments typically take 1-2.5 h each, and global analysis usually takes 10-20 min.

  15. Modulation of global low-frequency motions underlies allosteric regulation: demonstration in CRP/FNR family transcription factors.

    Rodgers, Thomas L; Townsend, Philip D; Burnell, David; Jones, Matthew L; Richards, Shane A; McLeish, Tom C B; Pohl, Ehmke; Wilson, Mark R; Cann, Martin J

    2013-09-01

    Allostery is a fundamental process by which ligand binding to a protein alters its activity at a distinct site. There is growing evidence that allosteric cooperativity can be communicated by modulation of protein dynamics without conformational change. The mechanisms, however, for communicating dynamic fluctuations between sites are debated. We provide a foundational theory for how allostery can occur as a function of low-frequency dynamics without a change in structure. We have generated coarse-grained models that describe the protein backbone motions of the CRP/FNR family transcription factors, CAP of Escherichia coli and GlxR of Corynebacterium glutamicum. The latter we demonstrate as a new exemplar for allostery without conformation change. We observe that binding the first molecule of cAMP ligand is correlated with modulation of the global normal modes and negative cooperativity for binding the second cAMP ligand without a change in mean structure. The theory makes key experimental predictions that are tested through an analysis of variant proteins by structural biology and isothermal calorimetry. Quantifying allostery as a free energy landscape revealed a protein "design space" that identified the inter- and intramolecular regulatory parameters that frame CRP/FNR family allostery. Furthermore, through analyzing CAP variants from diverse species, we demonstrate an evolutionary selection pressure to conserve residues crucial for allosteric control. This finding provides a link between the position of CRP/FNR transcription factors within the allosteric free energy landscapes and evolutionary selection pressures. Our study therefore reveals significant features of the mechanistic basis for allostery. Changes in low-frequency dynamics correlate with allosteric effects on ligand binding without the requirement for a defined spatial pathway. In addition to evolving suitable three-dimensional structures, CRP/FNR family transcription factors have been selected to

  16. Modulation of global low-frequency motions underlies allosteric regulation: demonstration in CRP/FNR family transcription factors.

    Thomas L Rodgers

    2013-09-01

    Full Text Available Allostery is a fundamental process by which ligand binding to a protein alters its activity at a distinct site. There is growing evidence that allosteric cooperativity can be communicated by modulation of protein dynamics without conformational change. The mechanisms, however, for communicating dynamic fluctuations between sites are debated. We provide a foundational theory for how allostery can occur as a function of low-frequency dynamics without a change in structure. We have generated coarse-grained models that describe the protein backbone motions of the CRP/FNR family transcription factors, CAP of Escherichia coli and GlxR of Corynebacterium glutamicum. The latter we demonstrate as a new exemplar for allostery without conformation change. We observe that binding the first molecule of cAMP ligand is correlated with modulation of the global normal modes and negative cooperativity for binding the second cAMP ligand without a change in mean structure. The theory makes key experimental predictions that are tested through an analysis of variant proteins by structural biology and isothermal calorimetry. Quantifying allostery as a free energy landscape revealed a protein "design space" that identified the inter- and intramolecular regulatory parameters that frame CRP/FNR family allostery. Furthermore, through analyzing CAP variants from diverse species, we demonstrate an evolutionary selection pressure to conserve residues crucial for allosteric control. This finding provides a link between the position of CRP/FNR transcription factors within the allosteric free energy landscapes and evolutionary selection pressures. Our study therefore reveals significant features of the mechanistic basis for allostery. Changes in low-frequency dynamics correlate with allosteric effects on ligand binding without the requirement for a defined spatial pathway. In addition to evolving suitable three-dimensional structures, CRP/FNR family transcription factors have

  17. Precision in robotic rectal surgery using the da Vinci Xi system and integrated table motion, a technical note.

    Panteleimonitis, Sofoklis; Harper, Mick; Hall, Stuart; Figueiredo, Nuno; Qureshi, Tahseen; Parvaiz, Amjad

    2017-09-15

    Robotic rectal surgery is becoming increasingly more popular among colorectal surgeons. However, time spent on robotic platform docking, arm clashing and undocking of the platform during the procedure are factors that surgeons often find cumbersome and time consuming. The newest surgical platform, the da Vinci Xi, coupled with integrated table motion can help to overcome these problems. This technical note aims to describe a standardised operative technique of single docking robotic rectal surgery using the da Vinci Xi system and integrated table motion. A stepwise approach of the da Vinci docking process and surgical technique is described accompanied by an intra-operative video that demonstrates this technique. We also present data collected from a prospectively maintained database. 33 consecutive rectal cancer patients (24 male, 9 female) received robotic rectal surgery with the da Vinci Xi during the preparation of this technical note. 29 (88%) patients had anterior resections, and four (12%) had abdominoperineal excisions. There were no conversions, no anastomotic leaks and no mortality. Median operation time was 331 (249-372) min, blood loss 20 (20-45) mls and length of stay 6.5 (4-8) days. 30-day readmission rate and re-operation rates were 3% (n = 1). This standardised technique of single docking robotic rectal surgery with the da Vinci Xi is safe, feasible and reproducible. The technological advances of the new robotic system facilitate the totally robotic single docking approach.

  18. An integrated bioimpedance—ECG gating technique for respiratory and cardiac motion compensation in cardiac PET

    Koivumäki, Tuomas; Nekolla, Stephan G; Fürst, Sebastian; Loher, Simone; Schwaiger, Markus; Vauhkonen, Marko; Hakulinen, Mikko A

    2014-01-01

    Respiratory motion may degrade image quality in cardiac PET imaging. Since cardiac PET studies often involve cardiac gating by ECG, a separate respiratory monitoring system is required increasing the logistic complexity of the examination, in case respiratory gating is also needed. Thus, we investigated the simultaneous acquisition of both respiratory and cardiac gating signals using II limb lead mimicking electrode configuration during cardiac PET scans of 11 patients. In addition to conventional static and ECG-gated images, bioimpedance technique was utilized to generate respiratory- and dual-gated images. The ability of the bioimpedance technique to monitor intrathoracic respiratory motion was assessed estimating cardiac displacement between end-inspiration and -expiration. The relevance of dual gating was evaluated in left ventricular volume and myocardial wall thickness measurements. An average 7.6  ±  3.3 mm respiratory motion was observed in the study population. Dual gating showed a small but significant increase (4 ml, p = 0.042) in left ventricular myocardial volume compared to plain cardiac gating. In addition, a thinner myocardial wall was observed in dual-gated images (9.3  ±  1.3 mm) compared to cardiac-gated images (11.3  ±  1.3 mm, p = 0.003). This study shows the feasibility of bioimpedance measurements for dual gating in a clinical setting. The method enables simultaneous acquisition of respiratory and cardiac gating signals using a single device with standard ECG electrodes. (paper)

  19. Assessment of the Global and Regional Land Hydrosphere and Its Impact on the Balance of the Geophysical Excitation Function of Polar Motion

    Wińska, Małgorzata; Nastula, Jolanta; Kołaczek, Barbara

    2016-02-01

    The impact of continental hydrological loading from land water, snow and ice on polar motion excitation, calculated as hydrological angular momentum (HAM), is difficult to estimate, and not as much is known about it as about atmospheric angular momentum (AAM) and oceanic angular momentum (OAM). In this paper, regional hydrological excitations to polar motion are investigated using monthly terrestrial water storage data derived from the Gravity Recovery and Climate Experiment (GRACE) mission and from the five models of land hydrology. The results show that the areas where the variance shows large variability are similar for the different models of land hydrology and for the GRACE data. Areas which have a small amplitude on the maps make an important contribution to the global hydrological excitation function of polar motion. The comparison of geodetic residuals and global hydrological excitation functions of polar motion shows that none of the hydrological excitation has enough energy to significantly improve the agreement between the observed geodetic excitation and geophysical ones.

  20. GLOFRIM v1.0 – A globally applicable computational framework for integrated hydrological–hydrodynamic modelling

    Hoch, J.M.; Neal, Jeffrey; Baart, Fedor; van Beek, L.P.H.; Winsemius, Hessel; Bates, Paul; Bierkens, M.F.P.

    2017-01-01

    We here present GLOFRIM, a globally applicable computational framework for integrated hydrological–hydrodynamic modelling. GLOFRIM facilitates spatially explicit coupling of hydrodynamic and hydrologic models and caters for an ensemble of models to be coupled. It currently encompasses the global

  1. Path integral for spinning particle in the plane wave field: Global and local projections

    Boudiaf, N.; Boudjedaa, T.; Chetouani, L.

    2001-01-01

    The Green function related to the problem of a Dirac particle interacting with a plane wave is calculated via the path integral formalism proposed recently by Alexandrou et al. according to the two so-called global and local projections. With the help of the incorporation of two simple identities, it is shown that the contribution to the calculation of the integrals comes essentially from classical solutions projected along the direction of wave propagation. (orig.)

  2. Semantic Data Integration and Ontology Use within the Global Earth Observation System of Systems (GEOSS) Global Water Cycle Data Integration System

    Pozzi, W.; Fekete, B.; Piasecki, M.; McGuinness, D.; Fox, P.; Lawford, R.; Vorosmarty, C.; Houser, P.; Imam, B.

    2008-12-01

    The inadequacies of water cycle observations for monitoring long-term changes in the global water system, as well as their feedback into the climate system, poses a major constraint on sustainable development of water resources and improvement of water management practices. Hence, The Group on Earth Observations (GEO) has established Task WA-08-01, "Integration of in situ and satellite data for water cycle monitoring," an integrative initiative combining different types of satellite and in situ observations related to key variables of the water cycle with model outputs for improved accuracy and global coverage. This presentation proposes development of the Rapid, Integrated Monitoring System for the Water Cycle (Global-RIMS)--already employed by the GEO Global Terrestrial Network for Hydrology (GTN-H)--as either one of the main components or linked with the Asian system to constitute the modeling system of GEOSS for water cycle monitoring. We further propose expanded, augmented capability to run multiple grids to embrace some of the heterogeneous methods and formats of the Earth Science, Hydrology, and Hydraulic Engineering communities. Different methodologies are employed by the Earth Science (land surface modeling), the Hydrological (GIS), and the Hydraulic Engineering Communities; with each community employing models that require different input data. Data will be routed as input variables to the models through web services, allowing satellite and in situ data to be integrated together within the modeling framework. Semantic data integration will provide the automation to enable this system to operate in near-real-time. Multiple data collections for ground water, precipitation, soil moisture satellite data, such as SMAP, and lake data will require multiple low level ontologies, and an upper level ontology will permit user-friendly water management knowledge to be synthesized. These ontologies will have to have overlapping terms mapped and linked together. so

  3. Integrated Motion Planning and Autonomous Control Technology for Autonomous ISR, Phase I

    National Aeronautics and Space Administration — SSCI and MIT propose to design, implement and test a comprehensive Integrated Mission Planning \\ (ii) Develop, Implement (iii) Develop, Implement and (iii) Carry...

  4. Paved with good intentions: global financial integration and the eurozone’s response

    Underhill, G.R.D.

    2011-01-01

    Regional governance systems may resolve the dilemmas of global financial integration, and the Eurozone is the most advanced attempt to do so. The Euroland sovereign debt crisis is a test of this proposition but the outcome finds the EU wanting. The first section places EMU in the broader context of

  5. How integration of global omics-data could help preparing for pandemics - a scent of influenza

    Bos, Lieuwe D. J.; de Jong, Menno D.; Sterk, Peter J.; Schultz, Marcus J.

    2014-01-01

    Pandemics caused by novel emerging or re-emerging infectious diseases could lead to high mortality and morbidity world-wide when left uncontrolled. In this perspective, we evaluate the possibility of integration of global omics-data in order to timely prepare for pandemics. Such an approach requires

  6. The Influence of Globalization, Integration and Regionalization Processes on the European States and Regions

    T V Bazarenko

    2013-12-01

    Full Text Available The article deals with the impact of globalization, regionalization and integration in European countries and regions. It discusses the distinctive features and factors of influence of each of these processes on the European countries and sub national entities.

  7. Transient feedback from fuel motion in metal IFR [Integral Fast Reactor] fuel

    Rhodes, E.A.; Stanford, G.S.; Regis, J.P.; Bauer, T.H.; Dickerman, C.E.

    1990-01-01

    Results from hodoscope data analyses are presented for TREAT transient-overpower tests M5 through M7 with emphasis on transient feedback mechanisms, including prefailure expansion at the tops of the fuel pins, subsequent dispersive axial fuel motion, and losses in relative worth of the fuel pins during the tests. Tests M5 and M6 were the first TOP tests of margin to cladding branch and prefailure elongation of D9-clad ternary (U-Pu-Zr) IFR-type fuel. Test M7 extended these results to high-burnup fuel and also initiated transient testing of HT9-clad binary (U-Zr) FFTF-driver fuel. Results show significant prefailure negative reactivity feedback and strongly negative feedback from fuel driven to failure. 4 refs., 6 figs

  8. MetaTracker: integration and abstraction of 3D motion tracking data from multiple hardware systems

    Kopecky, Ken; Winer, Eliot

    2014-06-01

    Motion tracking has long been one of the primary challenges in mixed reality (MR), augmented reality (AR), and virtual reality (VR). Military and defense training can provide particularly difficult challenges for motion tracking, such as in the case of Military Operations in Urban Terrain (MOUT) and other dismounted, close quarters simulations. These simulations can take place across multiple rooms, with many fast-moving objects that need to be tracked with a high degree of accuracy and low latency. Many tracking technologies exist, such as optical, inertial, ultrasonic, and magnetic. Some tracking systems even combine these technologies to complement each other. However, there are no systems that provide a high-resolution, flexible, wide-area solution that is resistant to occlusion. While frameworks exist that simplify the use of tracking systems and other input devices, none allow data from multiple tracking systems to be combined, as if from a single system. In this paper, we introduce a method for compensating for the weaknesses of individual tracking systems by combining data from multiple sources and presenting it as a single tracking system. Individual tracked objects are identified by name, and their data is provided to simulation applications through a server program. This allows tracked objects to transition seamlessly from the area of one tracking system to another. Furthermore, it abstracts away the individual drivers, APIs, and data formats for each system, providing a simplified API that can be used to receive data from any of the available tracking systems. Finally, when single-piece tracking systems are used, those systems can themselves be tracked, allowing for real-time adjustment of the trackable area. This allows simulation operators to leverage limited resources in more effective ways, improving the quality of training.

  9. Integration of canal and otolith inputs by central vestibular neurons is subadditive for both active and passive self-motion: implication for perception.

    Carriot, Jerome; Jamali, Mohsen; Brooks, Jessica X; Cullen, Kathleen E

    2015-02-25

    Traditionally, the neural encoding of vestibular information is studied by applying either passive rotations or translations in isolation. However, natural vestibular stimuli are typically more complex. During everyday life, our self-motion is generally not restricted to one dimension, but rather comprises both rotational and translational motion that will simultaneously stimulate receptors in the semicircular canals and otoliths. In addition, natural self-motion is the result of self-generated and externally generated movements. However, to date, it remains unknown how information about rotational and translational components of self-motion is integrated by vestibular pathways during active and/or passive motion. Accordingly, here, we compared the responses of neurons at the first central stage of vestibular processing to rotation, translation, and combined motion. Recordings were made in alert macaques from neurons in the vestibular nuclei involved in postural control and self-motion perception. In response to passive stimulation, neurons did not combine canal and otolith afferent information linearly. Instead, inputs were subadditively integrated with a weighting that was frequency dependent. Although canal inputs were more heavily weighted at low frequencies, the weighting of otolith input increased with frequency. In response to active stimulation, neuronal modulation was significantly attenuated (∼ 70%) relative to passive stimulation for rotations and translations and even more profoundly attenuated for combined motion due to subadditive input integration. Together, these findings provide insights into neural computations underlying the integration of semicircular canal and otolith inputs required for accurate posture and motor control, as well as perceptual stability, during everyday life. Copyright © 2015 the authors 0270-6474/15/353555-11$15.00/0.

  10. A computational method for direct integration of motion equations of structural systems

    Brusa, L.; Ciacci, R.; Creco, A.; Rossi, F.

    1975-01-01

    The dynamic analysis of structural systems requires the solution of the matrix equations: Md 2 delta/dt(t) + Cddelta/dt(t) + Kdelta(t) = F(t). Many numerical methods are available for direct integration of this equation and their efficiency is due to the fulfillment of the following requirements: A reasonable order of accuracy must be obtained for the approximation of the response relevant to the first modes: the model contributions relevant to the eigenvalues with large real part must be essentially neglected. This paper presents a step-by-step numerical scheme for the integration of this equation which satisfies the requirements previously mentioned. (Auth.)

  11. Integrating motion-detection cameras and hair snags for wolverine identification

    Audrey J. Magoun; Clinton D. Long; Michael K. Schwartz; Kristine L. Pilgrim; Richard E. Lowell; Patrick Valkenburg

    2011-01-01

    We developed an integrated system for photographing a wolverine's (Gulo gulo) ventral pattern while concurrently collecting hair for microsatellite DNA genotyping. Our objectives were to 1) test the system on a wild population of wolverines using an array of camera and hair-snag (C&H) stations in forested habitat where wolverines were known to occur, 2)...

  12. Integrated regional changes in arctic climate feedbacks: Implications for the global climate system

    McGuire, A.D.; Chapin, F. S.; Walsh, J.E.; Wirth, C.; ,

    2006-01-01

    The Arctic is a key part of the global climate system because the net positive energy input to the tropics must ultimately be resolved through substantial energy losses in high-latitude regions. The Arctic influences the global climate system through both positive and negative feedbacks that involve physical, ecological, and human systems of the Arctic. The balance of evidence suggests that positive feedbacks to global warming will likely dominate in the Arctic during the next 50 to 100 years. However, the negative feedbacks associated with changing the freshwater balance of the Arctic Ocean might abruptly launch the planet into another glacial period on longer timescales. In light of uncertainties and the vulnerabilities of the climate system to responses in the Arctic, it is important that we improve our understanding of how integrated regional changes in the Arctic will likely influence the evolution of the global climate system. Copyright ?? 2006 by Annual Reviews. All rights reserved.

  13. Integration and disintegration processes of ethnic communities in a globalized world: challenges and trends

    A. A. Paronikian

    2016-06-01

    Full Text Available The article examines the challenges and trends in integration and disintegration processes of ethnic communities in the world of globalization. Established that ethnic disintegration is inevitable consequence of ethnic integration, and its intensity depends on what method is carried Integration: voluntary or forced. What is important is the fact that in the era of globalization integration and disintegration processes of ethnic communities that are inherent in the very essence of ethnicity, greatly amplified. It was found that entering to the cultural field of ethnic communities of other ethnic entities, penalized sustainable ethnic balance, contributes to the phenomenon of «rejection of other» causes of ethnic conflict and the consequent threat of disintegration of ethnic communities. Disintegration often leads to weakening of the linkages and interactions between components of the integrated system in a multi-ethnic society. However, the author concludes that the process of disintegration cannot be regarded as unambiguously negative because, on the one hand, it contributes to the weakening and decline; and sometimes division of multi-ethnic countries, but on the other hand - it contributes to the birth of the new and revival of the old nation-states, which is particularly important in conditions of transformation of the global community towards the post-industrial and information epoch in the future. In general, the integration and disintegration change each other depending on global processes and their transformations. Therefore, in the era of globalization’s challenges it is important is the effective management of these processes to prevent adverse effects.

  14. The recent activities of nuclear power globalization. Our provision against global warming by global deployment of our own technologies as integrated nuclear power plant supply company'

    Yamauchi, Kiyoshi; Suzuki, Shigemitsu

    2008-01-01

    Mitsubishi Heavy Industries, Ltd. (MHI) is striving to expand and spread nuclear power plants as an 'Integrated Nuclear Power Plant Supply Company' based on its engineering, manufacturing, and technological support capabilities. The company also has ample experience in the export of major components. MHI is accelerating its global deployment through the market introduction of large-sized strategic reactor US-APWR, the joint development of a mid-sized strategic reactor ATMEA1 with AREVA, and a small strategic reactor PBMR. The company also plans to internationally deploy technologies for the nuclear fuel cycle. We present here the leading-edge trends in the global deployment of these nuclear businesses, all of which help to solve the energy and environmental issues in the world. (author)

  15. Path probability distribution of stochastic motion of non dissipative systems: a classical analog of Feynman factor of path integral

    Lin, T.L.; Wang, R.; Bi, W.P.; El Kaabouchi, A.; Pujos, C.; Calvayrac, F.; Wang, Q.A.

    2013-01-01

    We investigate, by numerical simulation, the path probability of non dissipative mechanical systems undergoing stochastic motion. The aim is to search for the relationship between this probability and the usual mechanical action. The model of simulation is a one-dimensional particle subject to conservative force and Gaussian random displacement. The probability that a sample path between two fixed points is taken is computed from the number of particles moving along this path, an output of the simulation, divided by the total number of particles arriving at the final point. It is found that the path probability decays exponentially with increasing action of the sample paths. The decay rate increases with decreasing randomness. This result supports the existence of a classical analog of the Feynman factor in the path integral formulation of quantum mechanics for Hamiltonian systems

  16. Implementation and Validation of EtherCAT Support in Integrated Development Environment for Synchronized Motion Control Application

    Lee, Jongbo; Kim, Chaerin; Kim, Ikhwan; Kim, Youngdong; Kim, Taehyoun [Univ. of Seoul, Seoul (Korea, Republic of)

    2014-02-15

    Recently, software-based programmable logic controller (PLC) systems, which are implemented in standard PLC languages on general hardware, are gaining popularity because they overcome the limitations of classical hardware PLC systems. Another noticeable trend is that the use of integrated development environment (IDE) is becoming important. IDEs can help developers to easily manage the growing complexity of modern control systems. Furthermore, industrial Ethernet, e. g. EtherCAT, is becoming widely accepted as a replacement for conventional fieldbuses in the distributed control domain because it offers favorable features such as short transmission delay, high bandwidth, and low cost. In this paper, we implemented the extension of open source IDE, called Beremiz, for developing EtherCAT-based real-time, synchronized motion control applications. We validated the EtherCAT system management features and the real-time responsiveness of the control function by using commercial EtherCAT drives and evaluation boards.

  17. Path integral approach for quantum motion on spaces of non-constant curvature according to Koenigs - Three dimensions

    Grosche, C.

    2007-08-01

    In this contribution a path integral approach for the quantum motion on three-dimensional spaces according to Koenigs, for short''Koenigs-Spaces'', is discussed. Their construction is simple: One takes a Hamiltonian from three-dimensional flat space and divides it by a three-dimensional superintegrable potential. Such superintegrable potentials will be the isotropic singular oscillator, the Holt-potential, the Coulomb potential, or two centrifugal potentials, respectively. In all cases a non-trivial space of non-constant curvature is generated. In order to obtain a proper quantum theory a curvature term has to be incorporated into the quantum Hamiltonian. For possible bound-state solutions we find equations up to twelfth order in the energy E. (orig.)

  18. Exact Mathisson-Papapetrou equations in the Schwarzschild metric with integrals of motion

    Plyatsko, R.M.; Stefanishin, O.B.

    2011-01-01

    A new representation for exact Mathisson-Papapetrou equations under the Mathisson-Pirani condition in the Schwarzschild gravitational field, which does not contain third-order derivatives with respect to spinning particle coordinates, has been obtained. For this purpose, the integrals of energy and angular momentum of a spinning particle, as well as a differential relation following from the Mathisson-Papapetrou equations for an arbitrary metric, are used.

  19. Results of stretched wire field integral measurements on the mini-undulator magnet - comparison of results obtained from circular and translational motion of the integrating wire

    Solomon, L.

    1998-05-01

    Measurements of the multipole content of the Mini-Undulator magnet have been made with two different integrating wire techniques. Both measurements used 43 strand Litz wire stretched along the length of the magnet within the magnet gap. In the first technique, the wire motion was purely translational, while in the second technique the wire was moved along a circular path. The induced voltage in the Litz wire was input into a Walker integrator, and the integrator output was analyzed as a function of wire position for determination of the multipole content of the magnetic field. The mini-undulator magnet is a 10 period, 80 mm per period hybrid insertion device. For all the data contained herein the magnet gap was set at 49 mm. In the mini-undulator magnet, the iron poles are 18mm x 32mm x 86 mm, and the Samarium Cobalt permanent magnet blocks are 22mm x 21mm x 110mm. For this magnet, which is a shortened prototype for the NSLS Soft X-Ray Undulator Magnet, the undulator parameter K = 0.934 B (Tesla)λ(cm), and B(tesla) = 0.534/sinh(πGap/λ). At a gap of 49 mm, the magnetic field is 1590 Gauss

  20. The role of size constancy for the integration of local elements into a global shape

    Johannes eRennig

    2013-07-01

    Full Text Available Visual perception depends on the visual context and is likely to be influenced by size constancy, which predicts a size and distance invariant perception of objects. However, size constancy can also result in optical illusions that allow the manipulation of the perceived size. We thus asked whether the integration of local elements into a global object can be influenced by manipulations of the visual context and size constancy? A set of stimuli was applied in healthy individuals that took advantage of the ‘Kanizsa’ illusion, in which three circles with open wedges oriented towards a center point are placed to form an illusionary perception of a triangle. In addition, a 3D-perspective view was implemented in which the global target (‘Kanizsa’ triangle was placed in combination with several distractor circles either in a close or a distant position. Subjects were engaged in a global recognition task on the location of the ‘Kanizsa’ triangle. Global recognition of ‘Kanizsa’ triangles improved with a decreasing length of the illusory contour. Interestingly, recognition of ‘Kanizsa’ triangles decreased when they were perceived as if they were located further away. We conclude that the integration of local elements into a global object is dependent on the visual context and dominated by size constancy.

  1. Infrared and visible images registration with adaptable local-global feature integration for rail inspection

    Tang, Chaoqing; Tian, Gui Yun; Chen, Xiaotian; Wu, Jianbo; Li, Kongjing; Meng, Hongying

    2017-12-01

    Active thermography provides infrared images that contain sub-surface defect information, while visible images only reveal surface information. Mapping infrared information to visible images offers more comprehensive visualization for decision-making in rail inspection. However, the common information for registration is limited due to different modalities in both local and global level. For example, rail track which has low temperature contrast reveals rich details in visible images, but turns blurry in the infrared counterparts. This paper proposes a registration algorithm called Edge-Guided Speeded-Up-Robust-Features (EG-SURF) to address this issue. Rather than sequentially integrating local and global information in matching stage which suffered from buckets effect, this algorithm adaptively integrates local and global information into a descriptor to gather more common information before matching. This adaptability consists of two facets, an adaptable weighting factor between local and global information, and an adaptable main direction accuracy. The local information is extracted using SURF while the global information is represented by shape context from edges. Meanwhile, in shape context generation process, edges are weighted according to local scale and decomposed into bins using a vector decomposition manner to provide more accurate descriptor. The proposed algorithm is qualitatively and quantitatively validated using eddy current pulsed thermography scene in the experiments. In comparison with other algorithms, better performance has been achieved.

  2. Retrospective feasibility study of simultaneous integrated boost in cervical cancer using Tomotherapy: the impact of organ motion and tumor regression.

    Herrera, Fernanda G; Callaway, Sharon; Delikgoz-Soykut, Ela; Coskun, Mehtap; Porta, Laetitia; Meuwly, Jean-Yves; Soares-Rodrigues, Joao; Heym, Leonie; Moeckli, Raphael; Ozsahin, Mahmut

    2013-01-03

    Whole pelvis intensity modulated radiotherapy (IMRT) is increasingly being used to treat cervical cancer aiming to reduce side effects. Encouraged by this, some groups have proposed the use of simultaneous integrated boost (SIB) to target the tumor, either to get a higher tumoricidal effect or to replace brachytherapy. Nevertheless, physiological organ movement and rapid tumor regression throughout treatment might substantially reduce any benefit of this approach. To evaluate the clinical target volume - simultaneous integrated boost (CTV-SIB) regression and motion during chemo-radiotherapy (CRT) for cervical cancer, and to monitor treatment progress dosimetrically and volumetrically to ensure treatment goals are met. Ten patients treated with standard doses of CRT and brachytherapy were retrospectively re-planned using a helical Tomotherapy - SIB technique for the hypothetical scenario of this feasibility study. Target and organs at risk (OAR) were contoured on deformable fused planning-computed tomography and megavoltage computed tomography images. The CTV-SIB volume regression was determined. The center of mass (CM) was used to evaluate the degree of motion. The Dice's similarity coefficient (DSC) was used to assess the spatial overlap of CTV-SIBs between scans. A cumulative dose-volume histogram modeled estimated delivered doses. The CTV-SIB relative reduction was between 31 and 70%. The mean maximum CM change was 12.5, 9, and 3 mm in the superior-inferior, antero-posterior, and right-left dimensions, respectively. The CTV-SIB-DSC approached 1 in the first week of treatment, indicating almost perfect overlap. CTV-SIB-DSC regressed linearly during therapy, and by the end of treatment was 0.5, indicating 50% discordance. Two patients received less than 95% of the prescribed dose. Much higher doses to the OAR were observed. A multiple regression analysis showed a significant interaction between CTV-SIB reduction and OAR dose increase. The CTV-SIB had important

  3. Retrospective feasibility study of simultaneous integrated boost in cervical cancer using tomotherapy: the impact of organ motion and tumor regression

    Herrera, Fernanda G; Ozsahin, Mahmut; Callaway, Sharon; Delikgoz-Soykut, Ela; Coskun, Mehtap; Porta, Laetitia; Meuwly, Jean-Yves; Soares-Rodrigues, Joao; Heym, Leonie; Moeckli, Raphael

    2013-01-01

    Whole pelvis intensity modulated radiotherapy (IMRT) is increasingly being used to treat cervical cancer aiming to reduce side effects. Encouraged by this, some groups have proposed the use of simultaneous integrated boost (SIB) to target the tumor, either to get a higher tumoricidal effect or to replace brachytherapy. Nevertheless, physiological organ movement and rapid tumor regression throughout treatment might substantially reduce any benefit of this approach. To evaluate the clinical target volume - simultaneous integrated boost (CTV-SIB) regression and motion during chemo-radiotherapy (CRT) for cervical cancer, and to monitor treatment progress dosimetrically and volumetrically to ensure treatment goals are met. Ten patients treated with standard doses of CRT and brachytherapy were retrospectively re-planned using a helical Tomotherapy - SIB technique for the hypothetical scenario of this feasibility study. Target and organs at risk (OAR) were contoured on deformable fused planning-computed tomography and megavoltage computed tomography images. The CTV-SIB volume regression was determined. The center of mass (CM) was used to evaluate the degree of motion. The Dice’s similarity coefficient (DSC) was used to assess the spatial overlap of CTV-SIBs between scans. A cumulative dose-volume histogram modeled estimated delivered doses. The CTV-SIB relative reduction was between 31 and 70%. The mean maximum CM change was 12.5, 9, and 3 mm in the superior-inferior, antero-posterior, and right-left dimensions, respectively. The CTV-SIB-DSC approached 1 in the first week of treatment, indicating almost perfect overlap. CTV-SIB-DSC regressed linearly during therapy, and by the end of treatment was 0.5, indicating 50% discordance. Two patients received less than 95% of the prescribed dose. Much higher doses to the OAR were observed. A multiple regression analysis showed a significant interaction between CTV-SIB reduction and OAR dose increase. The CTV-SIB had important

  4. Retrospective feasibility study of simultaneous integrated boost in cervical cancer using tomotherapy: the impact of organ motion and tumor regression

    Herrera Fernanda G

    2013-01-01

    Full Text Available Abstract Background Whole pelvis intensity modulated radiotherapy (IMRT is increasingly being used to treat cervical cancer aiming to reduce side effects. Encouraged by this, some groups have proposed the use of simultaneous integrated boost (SIB to target the tumor, either to get a higher tumoricidal effect or to replace brachytherapy. Nevertheless, physiological organ movement and rapid tumor regression throughout treatment might substantially reduce any benefit of this approach. Purpose To evaluate the clinical target volume - simultaneous integrated boost (CTV-SIB regression and motion during chemo-radiotherapy (CRT for cervical cancer, and to monitor treatment progress dosimetrically and volumetrically to ensure treatment goals are met. Methods and materials Ten patients treated with standard doses of CRT and brachytherapy were retrospectively re-planned using a helical Tomotherapy - SIB technique for the hypothetical scenario of this feasibility study. Target and organs at risk (OAR were contoured on deformable fused planning-computed tomography and megavoltage computed tomography images. The CTV-SIB volume regression was determined. The center of mass (CM was used to evaluate the degree of motion. The Dice’s similarity coefficient (DSC was used to assess the spatial overlap of CTV-SIBs between scans. A cumulative dose-volume histogram modeled estimated delivered doses. Results The CTV-SIB relative reduction was between 31 and 70%. The mean maximum CM change was 12.5, 9, and 3 mm in the superior-inferior, antero-posterior, and right-left dimensions, respectively. The CTV-SIB-DSC approached 1 in the first week of treatment, indicating almost perfect overlap. CTV-SIB-DSC regressed linearly during therapy, and by the end of treatment was 0.5, indicating 50% discordance. Two patients received less than 95% of the prescribed dose. Much higher doses to the OAR were observed. A multiple regression analysis showed a significant interaction

  5. 78 FR 10181 - Global Quality Systems-An Integrated Approach To Improving Medical Product Safety; Public Workshop

    2013-02-13

    ...] Global Quality Systems--An Integrated Approach To Improving Medical Product Safety; Public Workshop... (AFDO), is announcing a public workshop entitled ``Global Quality Systems--An Integrated Approach to... topics concerning FDA requirements related to the production and marketing of drugs and/or devices...

  6. 2008 – SOME GLOBAL ISSUES AND THEIR IMPACT ON THE PROSPECTS OF FURTHER EUROPEAN UNION INTEGRATION

    Florin Bonciu

    2008-09-01

    Full Text Available The paper analyzes the implications of some global trends and developments on the prospects of further European Union integration. The transfer of attributes from member states to community institutions is a long term process which confronted numerous set-backs and re-launches. The hypothesis discussed in this paper refers to the fact that current developments in the global arena require fast decision making mechanisms involving very sensitive issues and these developments tend to shift the balance towards member states institutions.

  7. European integration dimension of Republic of Moldova as development path in a globalization setting

    Natalia ANTOCI

    2015-12-01

    Full Text Available In a global market economy, the opening towards outward, standard harmonization and convergence of national economies can create the necessary synergy in order to address the challenges of globalization. Republic of Moldova needs to develop partnership relations with European Union (EU countries, which have experience in relation to commodity markets, and without which it is difficult to modernize the economy and diversify its export. Moldova's integration into the European Union allows increasing dynamism and sustainability of the economic system of our country and allows implementing a new model of economic growth according to EU Member States' experience.

  8. The EU as a global ecological power: The logics of market integration

    Laurent, Eloi; Le Cacheux, Jacques

    2010-05-01

    In this paper, we try to show how the EU became a global ecological power, i.e. a power that influences environmental policies throughout the world. While the existing literature stresses the significance of normative power, regulatory politics and multi-level governance in this process, we highlight the importance of what we call the logics of market integration. By that we mean the decisive role of Single market integration in fostering convergence of environmental policies at the European level as well as in extending European influence at the global level. We illustrate our approach with the case of climate policy, detailing the EU's influence on economic instruments developed worldwide to mitigate climate change. (authors)

  9. An Image Matching Algorithm Integrating Global SRTM and Image Segmentation for Multi-Source Satellite Imagery

    Xiao Ling

    2016-08-01

    Full Text Available This paper presents a novel image matching method for multi-source satellite images, which integrates global Shuttle Radar Topography Mission (SRTM data and image segmentation to achieve robust and numerous correspondences. This method first generates the epipolar lines as a geometric constraint assisted by global SRTM data, after which the seed points are selected and matched. To produce more reliable matching results, a region segmentation-based matching propagation is proposed in this paper, whereby the region segmentations are extracted by image segmentation and are considered to be a spatial constraint. Moreover, a similarity measure integrating Distance, Angle and Normalized Cross-Correlation (DANCC, which considers geometric similarity and radiometric similarity, is introduced to find the optimal correspondences. Experiments using typical satellite images acquired from Resources Satellite-3 (ZY-3, Mapping Satellite-1, SPOT-5 and Google Earth demonstrated that the proposed method is able to produce reliable and accurate matching results.

  10. Conservative integration of rigid body motion by quaternion parameters with implicit constraints

    Nielsen, Martin Bjerre; Krenk, Steen

    2012-01-01

    An angular momentum and energy‐conserving time integration algorithm for rigid body rotation is formulated in terms of the quaternion parameters and the corresponding four‐component conjugate momentum vector via Hamilton's equations. The introduction of an extended mass matrix leads to a symmetric...... these equations via the set of momentum equations. Initially, the normalization of the quaternion array is introduced via a Lagrange multiplier. However, this Lagrange multiplier can be expressed explicitly in terms of the gradient of the external load potential, and elimination of the Lagrange multiplier from...... the final format leaves only an explicit projection applied to the external load potential gradient. An algorithm is developed by forming a finite increment of the Hamiltonian. This procedure identifies the proper selection of increments and mean values, and leads to an algorithm with conservation...

  11. Integrating place-specific livelihood and equity outcomes into global assessments of bioenergy deployment

    Creutzig, Felix; Corbera, Esteve; Bolwig, Simon

    2013-01-01

    -study research focused on first-generation biofuel crops to demonstrate that food, income, land and other assets such as health are key livelihood dimensions that can be impacted by such crops and we highlight how place-specific and global dynamics influence both aggregate and distributional outcomes across......Integrated assessment models suggest that the large-scale deployment of bioenergy could contribute to ambitious climate change mitigation efforts. However, such a shift would intensify the global competition for land, with possible consequences for 1.5 billion smallholder livelihoods...... these livelihood dimensions. We argue that place-specific production models and land tenure regimes mediate livelihood outcomes, which are also in turn affected by global and regional markets and their resulting equilibrium dynamics. The place-specific perspective suggests that distributional consequences...

  12. Toward a global norm against manipulating the integrity of financial data

    Maurer, Tim; Levite, Ariel; Perkovich, George

    2017-01-01

    The financial crisis that erupted in 2007 highlighted how important trust is for the global system and how fragile it can be. The 2016 Bangladesh central bank cyber incident exposed a new threat to financial stability and the unprecedented scale of the risk that malicious cyber actors pose to financial institutions. Beyond theft, using cyber operations to manipulate the integrity of data, in particular, poses a distinct and greater set of systemic risks than other forms of financial coercion....

  13. Financial Integration of European Money Market: from EMU to the Global Crisis and Beyond

    Avadanei Andreea; Avadanei Anamaria; Ghiba Nicolae

    2010-01-01

    The scope of this article is to illustrate the general issues relevant for understanding the implications of the global crisis on European money market integration. We structured our paper on chapters that present the evolution of the considered market from the launch of euro until the financial turmoil, its main features in the actual context, and the central banks response to the rising tensions on the money market. Given its function of channeling funds to enable banks to cover their most ...

  14. Integrated regional assessment of global climatic change. Lessons from the Mackenzie Basin Impact Study (MBIS)

    Cohen, Stewart J.

    1996-01-01

    This paper outlines the potential role integrated regional assessments of global climatic change scenarios could play in building better links between science and related policy concerns. The concept is illustrated through description of an ongoing case study from Canada-the Mackenzie Basin Impact Study (MBIS). As part of the Government of Canada's Green Plan, the Global Warming Science Program includes a study of regional impacts of global warming scenarios in the Mackenzie Basin, located in northwestern Canada. The MBIS is a six-year program focussing on potential climate-induced changes in the land and water resource base, and the implications of four scenarios of global climatic change on land use and economic policies in this region. These policy issues include interjurisdictional water management, sustainability of native lifestyles, economic development opportunities (agriculture, forestry, tourism, etc.), sustainability of ecosystems and infrastructure maintenance. MBIS is due to be completed in 1997. MBIS represents an attempt to address regional impacts by incorporating a 'family of integrators' into the study framework, and by directly involving stakeholders in planning and research activities. The experience in organizing and carrying out this project may provide some lessons for others interested in organizing regional or country studies

  15. Integrating Into the Global Economy Through Services. The Case of Romania

    Agnes Ghibuțiu

    2014-04-01

    Full Text Available Services represent a most important and dynamic frontier of international trade and investment. The steady expansion of trade in services and its relative resilience in the recent crisis, coupled with its key role in global production networks and its increasing potential in attracting investment provides new opportunities for countries to grow their economies and integrate into the global economy. Drawing on insights from current literature and relying on balance of payments and trade in value-added statistics, this paper examines the main developments shaping Romania’s services trade over the post-crisis years. Its aim is to assess whether the country is grabbing the new opportunities arising from services globalization. It finds that following the dramatic crisis-induced decline in the value and performance of Romania’s services trade, the outlook is now radically improving as evidenced by the strongly rebounding services flows and net exports. Nonetheless, the country’s integration into the global economy through services flows continues to remain below its potential.

  16. Integrating into the Global Economy through Services. The Case of Romania

    AGNES GHIBUŢIU

    2014-05-01

    Full Text Available Services represent a most important and dynamic frontier of international trade and investment. The steady expansion of trade in services and its relative resilience in the recent crisis, coupled with its key role in global production networks and its increasing potential in attracting investment provides new opportunities for countries to grow their economies and integrate into the global economy. Drawing on insights from current literature and relying on balance of payments and trade in value-added statistics, this paper examines the main developments shaping Romania’s services trade over the post-crisis years. Its aim is to assess whether the country is seizing the new opportunities arising from services globalization. It finds that following the dramatic crisis-induced decline in the value and performance of Romania’s services trade, the outlook is now radically improving as evidenced by strongly rebounding services flows and net exports. Nonetheless, the country’s integration into the global economy through services flows continues to remain below its potential.

  17. An integrated model for the assessment of global water resources – Part 2: Applications and assessments

    N. Hanasaki

    2008-07-01

    Full Text Available To assess global water resources from the perspective of subannual variation in water availability and water use, an integrated water resources model was developed. In a companion report, we presented the global meteorological forcing input used to drive the model and six modules, namely, the land surface hydrology module, the river routing module, the crop growth module, the reservoir operation module, the environmental flow requirement module, and the anthropogenic withdrawal module. Here, we present the results of the model application and global water resources assessments. First, the timing and volume of simulated agriculture water use were examined because agricultural use composes approximately 85% of total consumptive water withdrawal in the world. The estimated crop calendar showed good agreement with earlier reports for wheat, maize, and rice in major countries of production. In major countries, the error in the planting date was ±1 mo, but there were some exceptional cases. The estimated irrigation water withdrawal also showed fair agreement with country statistics, but tended to be underestimated in countries in the Asian monsoon region. The results indicate the validity of the model and the input meteorological forcing because site-specific parameter tuning was not used in the series of simulations. Finally, global water resources were assessed on a subannual basis using a newly devised index. This index located water-stressed regions that were undetected in earlier studies. These regions, which are indicated by a gap in the subannual distribution of water availability and water use, include the Sahel, the Asian monsoon region, and southern Africa. The simulation results show that the reservoir operations of major reservoirs (>1 km3 and the allocation of environmental flow requirements can alter the population under high water stress by approximately −11% to +5% globally. The integrated model is applicable to

  18. Entropy-based analysis and bioinformatics-inspired integration of global economic information transfer.

    Jinkyu Kim

    Full Text Available The assessment of information transfer in the global economic network helps to understand the current environment and the outlook of an economy. Most approaches on global networks extract information transfer based mainly on a single variable. This paper establishes an entirely new bioinformatics-inspired approach to integrating information transfer derived from multiple variables and develops an international economic network accordingly. In the proposed methodology, we first construct the transfer entropies (TEs between various intra- and inter-country pairs of economic time series variables, test their significances, and then use a weighted sum approach to aggregate information captured in each TE. Through a simulation study, the new method is shown to deliver better information integration compared to existing integration methods in that it can be applied even when intra-country variables are correlated. Empirical investigation with the real world data reveals that Western countries are more influential in the global economic network and that Japan has become less influential following the Asian currency crisis.

  19. Entropy-based analysis and bioinformatics-inspired integration of global economic information transfer.

    Kim, Jinkyu; Kim, Gunn; An, Sungbae; Kwon, Young-Kyun; Yoon, Sungroh

    2013-01-01

    The assessment of information transfer in the global economic network helps to understand the current environment and the outlook of an economy. Most approaches on global networks extract information transfer based mainly on a single variable. This paper establishes an entirely new bioinformatics-inspired approach to integrating information transfer derived from multiple variables and develops an international economic network accordingly. In the proposed methodology, we first construct the transfer entropies (TEs) between various intra- and inter-country pairs of economic time series variables, test their significances, and then use a weighted sum approach to aggregate information captured in each TE. Through a simulation study, the new method is shown to deliver better information integration compared to existing integration methods in that it can be applied even when intra-country variables are correlated. Empirical investigation with the real world data reveals that Western countries are more influential in the global economic network and that Japan has become less influential following the Asian currency crisis.

  20. Innovation in Hungary - The Impact of EU Accession and Integration into Global Value Chains

    Szalavetz Andrea

    2014-11-01

    Full Text Available This paper argues that EU accession has brought about minimal changes in the patterns of innovation in Hungary. The reason why is not that the ‘EU factor’ is of minor importance; rather, it is Hungary's inability to use EU resources effectively, so as to fully benefit from EU membership. The Hungarian story also demonstrates that the EU cannot block member states from reversing reform or abusing the opportunities EU membership offers to them. We contend that globalization (global value chain integration has more effectively contributed to Hungary's knowledge-based upgrading than Europeanization (in the sense of policy transfer; access to EU Structural & Cohesion Funds, and integration in the European Research Area. This argument is substantiated with a case study on innovation strategy design and implementation, which illustrates the ambiguous impact of Europeanization, which is contrasted with our investigation of integration in global value chains, conducted through interviews of foreign-owned manufacturing companies about their R&D-based upgrading experience.

  1. Connecting science and the musical arts in teaching tone quality: Integrating Helmholtz motion and master violin teachers' pedagogies

    Collins, Cheri D.

    Is it possible for students to achieve better tone quality from even their factory-made violins? All violins, regardless of cost, have a common capacity for good tone in certain frequencies. These signature modes outline the first position range of a violin (196-600 hertz). To activate this basic capacity of all violins, the string must fully vibrate. To accomplish this the bow must be pulled across the string with enough pressure (relative to its speed and contact point) for the horsehairs to catch. This friction permits the string to vibrate in Helmholtz Motion, which produces a corner that travels along the edge of the string between the bridge and the nut. Creating this corner is the most fundamental technique for achieving good tone. The findings of celebrated scientists Ernest Chladni, Hermann von Helmholtz, and John Schelleng will be discussed and the tone-production pedagogy of master teachers Carl Flesch, Ivan Galamian, Robert Gerle, and Simon Fischer will be investigated. Important connections between the insights of these scientists and master teachers are evident. Integrating science and art can provide teachers with a better understanding of the characteristics of good tone. This can help their students achieve the best possible sound from their instruments. In the private studio the master teacher may not use the words "Helmholtz Motion." Yet through modeling and listening students are able to understand and create a quality tone. Music teachers without experience in string performance may be assigned to teach strings in classroom and ensembles settings. As a result modeling good tone is not always possible. However, all teachers and conductors can understand the fundamental behavior of string vibration and adapt their instruction strategies towards student success. Better tonal quality for any string instrument is ultimately achieved. Mastery and use of the Helmholtz Motion benefits teachers and students alike. Simple practice exercises for teaching

  2. Smart Floor with Integrated Triboelectric Nanogenerator As Energy Harvester and Motion Sensor.

    He, Chuan; Zhu, Weijun; Chen, Baodong; Xu, Liang; Jiang, Tao; Han, Chang Bao; Gu, Guang Qin; Li, Dichen; Wang, Zhong Lin

    2017-08-09

    A smart floor is demonstrated by integrating a square-frame triboelectric nanogenerator (SF-TENG) into a standard wood floor. The smart floor has two working modes based on two pairs of triboelectric materials: one is purposely chosen polytetrafluoroethylene films and aluminum (Al) balls, and the other is the floor itself and the objects that can be triboelectrically charged, such as basketball, shoe soles, and Scotch tape, etc. Utilizing the Al balls enclosed inside shallow boxes, the smart floor is capable of harvesting vibrational energy and, hence, provides a nonintrusive way to detect sudden falls in elderly people. In addition, when the basketball is bounced repeatedly on the floor, the average output voltage and current are 364 ± 43 V and 9 ± 1 μA, respectively, and 87 serially connected light-emitting diodes can be lit up simultaneously. Furthermore, the friction between the triboelectrically chargeable objects and the floor can also induce an alternating current output in the external circuit without the vibration of the Al balls. Normal human footsteps on the floor produce a voltage of 238 ± 17 V and a current of 2.4 ± 0.3 μA. Therefore, this work presents a smart floor with built-in SF-TENG without compromising the flexibility and stability of the standard wood floor and also demonstrates a way to harvest ambient energy solely by using conventional triboelectric materials in our daily life.

  3. Integration of molecular pathology, epidemiology and social science for global precision medicine.

    Nishi, Akihiro; Milner, Danny A; Giovannucci, Edward L; Nishihara, Reiko; Tan, Andy S; Kawachi, Ichiro; Ogino, Shuji

    2016-01-01

    The precision medicine concept and the unique disease principle imply that each patient has unique pathogenic processes resulting from heterogeneous cellular genetic and epigenetic alterations and interactions between cells (including immune cells) and exposures, including dietary, environmental, microbial and lifestyle factors. As a core method field in population health science and medicine, epidemiology is a growing scientific discipline that can analyze disease risk factors and develop statistical methodologies to maximize utilization of big data on populations and disease pathology. The evolving transdisciplinary field of molecular pathological epidemiology (MPE) can advance biomedical and health research by linking exposures to molecular pathologic signatures, enhancing causal inference and identifying potential biomarkers for clinical impact. The MPE approach can be applied to any diseases, although it has been most commonly used in neoplastic diseases (including breast, lung and colorectal cancers) because of availability of various molecular diagnostic tests. However, use of state-of-the-art genomic, epigenomic and other omic technologies and expensive drugs in modern healthcare systems increases racial, ethnic and socioeconomic disparities. To address this, we propose to integrate molecular pathology, epidemiology and social science. Social epidemiology integrates the latter two fields. The integrative social MPE model can embrace sociology, economics and precision medicine, address global health disparities and inequalities, and elucidate biological effects of social environments, behaviors and networks. We foresee advancements of molecular medicine, including molecular diagnostics, biomedical imaging and targeted therapeutics, which should benefit individuals in a global population, by means of an interdisciplinary approach of integrative MPE and social health science.

  4. The response of terrestrial ecosystems to global climate change: Towards an integrated approach

    Rustad, Lindsey E.

    2008-01-01

    Accumulating evidence points to an anthropogenic 'fingerprint' on the global climate change that has occurred in the last century. Climate change has, and will continue to have, profound effects on the structure and function of terrestrial ecosystems. As such, there is a critical need to continue to develop a sound scientific basis for national and international policies regulating carbon sequestration and greenhouse gas emissions. This paper reflects on the nature of current global change experiments, and provides recommendations for a unified multidisciplinary approach to future research in this dynamic field. These recommendations include: (1) better integration between experiments and models, and amongst experimental, monitoring, and space-for-time studies; (2) stable and increased support for long-term studies and multi-factor experiments; (3) explicit inclusion of biodiversity, disturbance, and extreme events in experiments and models; (4) consideration of timing vs intensity of global change factors in experiments and models; (5) evaluation of potential thresholds or ecosystem 'tipping points'; and (6) increased support for model-model and model-experiment comparisons. These recommendations, which reflect discussions within the TERACC international network of global change scientists, will facilitate the unraveling of the complex direct and indirect effects of global climate change on terrestrial ecosystems and their components

  5. Globalization

    Tulio Rosembuj

    2006-12-01

    Full Text Available There is no singular globalization, nor is the result of an individual agent. We could start by saying that global action has different angles and subjects who perform it are different, as well as its objectives. The global is an invisible invasion of materials and immediate effects.

  6. Globalization

    Tulio Rosembuj

    2006-01-01

    There is no singular globalization, nor is the result of an individual agent. We could start by saying that global action has different angles and subjects who perform it are different, as well as its objectives. The global is an invisible invasion of materials and immediate effects.

  7. Integrating place-specific livelihood and equity outcomes into global assessments of bioenergy deployment

    Creutzig, Felix; Corbera, Esteve; Bolwig, Simon; Hunsberger, Carol

    2013-01-01

    Integrated assessment models suggest that the large-scale deployment of bioenergy could contribute to ambitious climate change mitigation efforts. However, such a shift would intensify the global competition for land, with possible consequences for 1.5 billion smallholder livelihoods that these models do not consider. Maintaining and enhancing robust livelihoods upon bioenergy deployment is an equally important sustainability goal that warrants greater attention. The social implications of biofuel production are complex, varied and place-specific, difficult to model, operationalize and quantify. However, a rapidly developing body of social science literature is advancing the understanding of these interactions. In this letter we link human geography research on the interaction between biofuel crops and livelihoods in developing countries to integrated assessments on biofuels. We review case-study research focused on first-generation biofuel crops to demonstrate that food, income, land and other assets such as health are key livelihood dimensions that can be impacted by such crops and we highlight how place-specific and global dynamics influence both aggregate and distributional outcomes across these livelihood dimensions. We argue that place-specific production models and land tenure regimes mediate livelihood outcomes, which are also in turn affected by global and regional markets and their resulting equilibrium dynamics. The place-specific perspective suggests that distributional consequences are a crucial complement to aggregate outcomes; this has not been given enough weight in comprehensive assessments to date. By narrowing the gap between place-specific case studies and global models, our discussion offers a route towards integrating livelihood and equity considerations into scenarios of future bioenergy deployment, thus contributing to a key challenge in sustainability sciences. (letter)

  8. Integrating place-specific livelihood and equity outcomes into global assessments of bioenergy deployment

    Creutzig, Felix; Corbera, Esteve; Bolwig, Simon; Hunsberger, Carol

    2013-09-01

    Integrated assessment models suggest that the large-scale deployment of bioenergy could contribute to ambitious climate change mitigation efforts. However, such a shift would intensify the global competition for land, with possible consequences for 1.5 billion smallholder livelihoods that these models do not consider. Maintaining and enhancing robust livelihoods upon bioenergy deployment is an equally important sustainability goal that warrants greater attention. The social implications of biofuel production are complex, varied and place-specific, difficult to model, operationalize and quantify. However, a rapidly developing body of social science literature is advancing the understanding of these interactions. In this letter we link human geography research on the interaction between biofuel crops and livelihoods in developing countries to integrated assessments on biofuels. We review case-study research focused on first-generation biofuel crops to demonstrate that food, income, land and other assets such as health are key livelihood dimensions that can be impacted by such crops and we highlight how place-specific and global dynamics influence both aggregate and distributional outcomes across these livelihood dimensions. We argue that place-specific production models and land tenure regimes mediate livelihood outcomes, which are also in turn affected by global and regional markets and their resulting equilibrium dynamics. The place-specific perspective suggests that distributional consequences are a crucial complement to aggregate outcomes; this has not been given enough weight in comprehensive assessments to date. By narrowing the gap between place-specific case studies and global models, our discussion offers a route towards integrating livelihood and equity considerations into scenarios of future bioenergy deployment, thus contributing to a key challenge in sustainability sciences.

  9. Challenges and Opportunities for Integrating Social Science Perspectives into Climate and Global Change Assessments

    Larson, E. K.; Li, J.; Zycherman, A.

    2017-12-01

    Integration of social science into climate and global change assessments is fundamental for improving understanding of the drivers, impacts and vulnerability of climate change, and the social, cultural and behavioral challenges related to climate change responses. This requires disciplinary and interdisciplinary knowledge as well as integrational and translational tools for linking this knowledge with the natural and physical sciences. The USGCRP's Social Science Coordinating Committee (SSCC) is tasked with this challenge and is working to integrate relevant social, economic and behavioral knowledge into processes like sustained assessments. This presentation will discuss outcomes from a recent SSCC workshop, "Social Science Perspectives on Climate Change" and their applications to sustained assessments. The workshop brought academic social scientists from four disciplines - anthropology, sociology, geography and archaeology - together with federal scientists and program managers to discuss three major research areas relevant to the USGCRP and climate assessments: (1) innovative tools, methods, and analyses to clarify the interactions of human and natural systems under climate change, (2) understanding of factors contributing to differences in social vulnerability between and within communities under climate change, and (3) social science perspectives on drivers of global climate change. These disciplines, collectively, emphasize the need to consider socio-cultural, political, economic, geographic, and historic factors, and their dynamic interactions, to understand climate change drivers, social vulnerability, and mitigation and adaptation responses. They also highlight the importance of mixed quantitative and qualitative methods to explain impacts, vulnerability, and responses at different time and spatial scales. This presentation will focus on major contributions of the social sciences to climate and global change research. We will discuss future directions for

  10. In-motion initial alignment and positioning with INS/CNS/ODO integrated navigation system for lunar rovers

    Lu, Jiazhen; Lei, Chaohua; Yang, Yanqiang; Liu, Ming

    2017-06-01

    Many countries have been paying great attention to space exploration, especially about the Moon and the Mars. Autonomous and high-accuracy navigation systems are needed for probers and rovers to accomplish missions. Inertial navigation system (INS)/celestial navigation system (CNS) based navigation system has been used widely on the lunar rovers. Initialization is a particularly important step for navigation. This paper presents an in-motion alignment and positioning method for lunar rovers by INS/CNS/odometer integrated navigation. The method can estimate not only the position and attitude errors, but also the biases of the accelerometers and gyros using the standard Kalman filter. The differences between the platform star azimuth, elevation angles and the computed star azimuth, elevation angles, and the difference between the velocity measured by odometer and the velocity measured by inertial sensors are taken as measurements. The semi-physical experiments are implemented to demonstrate that the position error can reduce to 10 m and attitude error is within 2″ during 5 min. The experiment results prove that it is an effective and attractive initialization approach for lunar rovers.

  11. An application of oscillation-damped motion for suspended payloads to the advanced integrated maintenance system in fuel cycle facilities

    Noakes, M.W.; Petterson, B.J.; Werner, J.C.

    1990-01-01

    The transportation of objects using overhead cranes can induce pendular motion of the object, which usually must be damped or allowed to decay before the next process can take place. Recent work at Sandia National Laboratories has shown that oscillation-damped transport and swing-free stops are possible by properly programming the acceleration of the transporting crane. Initial studies have been completed using a CIMCORP XR6100 gantry robot. The Advanced Integrated Maintenance System (AIMS) is an engineering and operations test bed developed for remote maintenance and handling studies within the Consolidated Fuel Reprocessing Program (CFRP) at Oak Ridge National Laboratory. The goal of CFRP has been to advanced the technology of in-cell systems planned for future nuclear fuel cycle facilities. The AIMS provides the capabilities to examine the needs and constraints necessary for hot-cell remote maintenance and includes a force-reflecting master/slave teleoperator and overhead transporter system. The associated control system provides a flexible programming environment conducive to controls experimentation. This paper reviews the theory associated with oscillation-damped trajectories for simply suspended objects and describes a specific implementation of the oscillation damping methods for the AIMS transporter. Hardware and software requirements and constraints for proper operation are discussed

  12. Experimental integrative muscular movement technique enhances cervical range of motion in patients with chronic neck pain: a pilot study.

    Rohe, Benjamin G; Carter, Ronald; Thompson, William R; Duncan, Randall L; Cooper, Carlton R

    2015-04-01

    Neck pain presents a tremendous physical and financial burden. This study compared the efficacy of the complementary and alternative medical treatments of integrative muscular movement technique (IMMT) and Swedish massage on neck pain in women of occupation age, the largest demographic group with neck pain. A total of 38 women were assigned to IMMT (n=28) or Swedish massage (n=10) in a blinded manner. Both groups received eight 30-minute treatments over 4 weeks. Cervical range of motion (ROM) in flexion, extension, sidebending, and rotation was measured before and after treatment. Each patient's pain was assessed by using an analogue pain scale of 0-10. Compared with the Swedish massage group, patients receiving IMMT experienced a significant increase in ROM in cervical flexion (ppain for IMMT was -1.75 units compared with -0.3 units for Swedish massage (pcervical ROM in every movement measured compared with Swedish massage. Inclusion of the IMMT in a treatment regimen for chronic neck pain may lead to decreased pain and increased cervical ROM. These positive effects of the IMMT intervention may have a role in enhancing functional outcomes in patients with neck pain.

  13. Stock return predictability and market integration: The role of global and local information

    David G. McMillan

    2016-12-01

    Full Text Available This paper examines the predictability of a range of international stock markets where we allow the presence of both local and global predictive factors. Recent research has argued that US returns have predictive power for international stock returns. We expand this line of research, following work on market integration, to include a more general definition of the global factor, based on principal components analysis. Results identify three global expected returns factors, one related to the major stock markets of the US, UK and Asia and one related to the other markets analysed. The third component is related to dividend growth. A single dominant realised returns factor is also noted. A forecasting exercise comparing the principal components based factors to a US return factor and local market only factors, as well as the historical mean benchmark finds supportive evidence for the former approach. It is hoped that the results from this paper will be informative on three counts. First, to academics interested in understanding the dynamics asset price movement. Second, to market participants who aim to time the market and engage in portfolio and risk management. Third, to those (policy makers and others who are interested in linkages across international markets and the nature and degree of integration.

  14. Global identification predicts gay-male identity integration and well-being among Turkish gay men.

    Koc, Yasin; Vignoles, Vivian L

    2016-12-01

    In most parts of the world, hegemonic masculinity requires men to endorse traditional masculine ideals, one of which is rejection of homosexuality. Wherever hegemonic masculinity favours heterosexuality over homosexuality, gay males may feel under pressure to negotiate their conflicting male gender and gay sexual identities to maintain positive self-perceptions. However, globalization, as a source of intercultural interaction, might provide a beneficial context for people wishing to create alternative masculinities in the face of hegemonic masculinity. Hence, we tested if global identification would predict higher levels of gay-male identity integration, and indirectly subjective well-being, via alternative masculinity representations for gay and male identities. A community sample of 219 gay and bisexual men from Turkey completed the study. Structural equation modelling revealed that global identification positively predicted gay-male identity integration, and indirectly subjective well-being; however, alternative masculinity representations did not mediate this relationship. Our findings illustrate how identity categories in different domains can intersect and affect each other in complex ways. Moreover, we discuss mental health and well-being implications for gay men living in cultures where they experience high levels of prejudice and stigma. © 2016 The British Psychological Society.

  15. Global search tool for the Advanced Photon Source Integrated Relational Model of Installed Systems (IRMIS) database

    Quock, D.E.R.; Cianciarulo, M.B.

    2007-01-01

    The Integrated Relational Model of Installed Systems (IRMIS) is a relational database tool that has been implemented at the Advanced Photon Source to maintain an updated account of approximately 600 control system software applications, 400,000 process variables, and 30,000 control system hardware components. To effectively display this large amount of control system information to operators and engineers, IRMIS was initially built with nine Web-based viewers: Applications Organizing Index, IOC, PLC, Component Type, Installed Components, Network, Controls Spares, Process Variables, and Cables. However, since each viewer is designed to provide details from only one major category of the control system, the necessity for a one-stop global search tool for the entire database became apparent. The user requirements for extremely fast database search time and ease of navigation through search results led to the choice of Asynchronous JavaScript and XML (AJAX) technology in the implementation of the IRMIS global search tool. Unique features of the global search tool include a two-tier level of displayed search results, and a database data integrity validation and reporting mechanism.

  16. Hybrid extended particle filter (HEPF) for integrated inertial navigation and global positioning systems

    Aggarwal, Priyanka; Syed, Zainab; El-Sheimy, Naser

    2009-01-01

    Navigation includes the integration of methodologies and systems for estimating time-varying position, velocity and attitude of moving objects. Navigation incorporating the integrated inertial navigation system (INS) and global positioning system (GPS) generally requires extensive evaluations of nonlinear equations involving double integration. Currently, integrated navigation systems are commonly implemented using the extended Kalman filter (EKF). The EKF assumes a linearized process, measurement models and Gaussian noise distributions. These assumptions are unrealistic for highly nonlinear systems like land vehicle navigation and may cause filter divergence. A particle filter (PF) is developed to enhance integrated INS/GPS system performance as it can easily deal with nonlinearity and non-Gaussian noises. In this paper, a hybrid extended particle filter (HEPF) is developed as an alternative to the well-known EKF to achieve better navigation data accuracy for low-cost microelectromechanical system sensors. The results show that the HEPF performs better than the EKF during GPS outages, especially when simulated outages are located in periods with high vehicle dynamics

  17. INTEGRATING COUNTRY-SPECIFIC CULTURE IN THE BRANDING STRATEGY FOR BUILDING GLOBAL SUCCESS

    Alexandra IOANID

    2014-11-01

    Full Text Available A strong brand is the one that integrates its cultural origins and values with the cultural values of the countries where it operates, building relationships based on trust with the local consumers. The chances for a company to gain share market when starting operations in a new country grows a lot if the management allows enough regional flexibility on how the brands are marketed, according to the cultural characteristics of the potential local customers. In the actual globalized business environment, the brand marketer has the choice to adopt a global or a local approach in the marketing strategy, that most of the times determines the success or the failure of the business in a specific country. An important challenge for any marketer is the integration of the brand-culture with the country-culture and in this context, the paper analyses different cultures and offers some branding strategies valid for both products and services. This paper aims to demonstrate the importance of the country-specific culture integration in the marketing strategy of a company for growing the effectiveness of all its operations. The ideas mentioned in this paper are based on literature research and also on authors’ experience with multicultural environments.

  18. An integrated model to simulate sown area changes for major crops at a global scale

    SHIBASAKI; Ryosuke

    2008-01-01

    Dynamics of land use systems have attracted much attention from scientists around the world due to their ecological and socio-economic implications. An integrated model to dynamically simulate future changes in sown areas of four major crops (rice, maize, wheat and soybean) on a global scale is pre- sented. To do so, a crop choice model was developed on the basis of Multinomial Logit (Logit) model to model land users’ decisions on crop choices among a set of available alternatives with using a crop utility function. A GIS-based Environmental Policy Integrated Climate (EPIC) model was adopted to simulate the crop yields under a given geophysical environment and farming management conditions, while the International Food Policy and Agricultural Simulation (IFPSIM) model was utilized to estimate crop price in the international market. The crop choice model was linked with the GIS-based EPIC model and the IFPSIM model through data exchange. This integrated model was then validated against the FAO statistical data in 2001-2003 and the Moderate Resolution Imaging Spectroradiometer (MODIS) global land cover product in 2001. Both validation approaches indicated reliability of the model for ad- dressing the dynamics in agricultural land use and its capability for long-term scenario analysis. Finally, the model application was designed to run over a time period of 30 a, taking the year 2000 as baseline. The model outcomes can help understand and explain the causes, locations and consequences of land use changes, and provide support for land use planning and policy making.

  19. The numerical assessment of motion strategies for integrated linear motor during starting of a free-piston engine generator

    Razali Hanipah, M.; Razul Razali, Akhtar

    2017-10-01

    Free-piston engine generator (FPEG) provides a novel method for electrical power generation in hybrid electric vehicle applications with scarcely reported prototype development and testing. This paper is looking into the motion control strategy for motoring the FPEG during starting. There are two motion profiles investigated namely, trapezoidal velocity and Scurve velocity. Both motion profiles were investigated numerically and the results have shown that the S-curve motion can only achieve 80% of the stroke when operated at the proposed motoring speed of 10Hz.

  20. Improving Remote Sensing Scene Classification by Integrating Global-Context and Local-Object Features

    Dan Zeng

    2018-05-01

    Full Text Available Recently, many researchers have been dedicated to using convolutional neural networks (CNNs to extract global-context features (GCFs for remote-sensing scene classification. Commonly, accurate classification of scenes requires knowledge about both the global context and local objects. However, unlike the natural images in which the objects cover most of the image, objects in remote-sensing images are generally small and decentralized. Thus, it is hard for vanilla CNNs to focus on both global context and small local objects. To address this issue, this paper proposes a novel end-to-end CNN by integrating the GCFs and local-object-level features (LOFs. The proposed network includes two branches, the local object branch (LOB and global semantic branch (GSB, which are used to generate the LOFs and GCFs, respectively. Then, the concatenation of features extracted from the two branches allows our method to be more discriminative in scene classification. Three challenging benchmark remote-sensing datasets were extensively experimented on; the proposed approach outperformed the existing scene classification methods and achieved state-of-the-art results for all three datasets.

  1. Wastewater Treatment Energy Recovery Potential For Adaptation To Global Change: An Integrated Assessment

    Breach, Patrick A.; Simonovic, Slobodan P.

    2018-04-01

    Approximately 20% of wastewaters globally do not receive treatment, whereas wastewater discharges are projected to increase, thereby leading to excessive water quality degradation of surface waters on a global scale. Increased treatment could help alleviate water quality issues by constructing more treatment plants; however, in many areas there exist economic constraints. Energy recovery methods including the utilization of biogas and incineration of biosolids generated during the treatment process may help to alleviate treatment costs. This study explores the potential for investments in energy recovery from wastewater to increase treatment levels and thus improve surface water quality. This was done by examining the relationships between nutrient over-enrichment, wastewater treatment, and energy recovery at a global scale using system dynamics simulation as part of the ANEMI integrated assessment model. The results show that a significant amount of energy can be recovered from wastewater, which helps to alleviate some of the costs of treatment. It was found that wastewater treatment levels could be increased by 34%, helping to offset the higher nutrient loading from a growing population with access to improved sanitation. The production of renewable natural gas from biogas was found to have the potential to prolong the depletion of natural gas resources used to produce electricity and heat. It is recommended that agricultural nutrient discharges be better managed to help reduce nutrient over-enrichment on global scale. To increase the utility of the simulation, a finer spatial scale should be used to consider regional treatment, economic, and water quality characteristics.

  2. Globalization

    Andru?cã Maria Carmen

    2013-01-01

    The field of globalization has highlighted an interdependence implied by a more harmonious understanding determined by the daily interaction between nations through the inducement of peace and the management of streamlining and the effectiveness of the global economy. For the functioning of the globalization, the developing countries that can be helped by the developed ones must be involved. The international community can contribute to the institution of the development environment of the gl...

  3. Global Positioning System (GPS) Receiver Autonomous Integrity Monitoring (RAIM) web service to support Area Navigation (RNAV) flight planning

    2008-01-28

    The Volpe Center designed, implemented, and deployed a Global Positioning System (GPS) Receiver Autonomous Integrity Monitoring (RAIM) prediction system in the mid 1990s to support both Air Force and Federal Aviation Administration (FAA) use of TSO C...

  4. An integrated model-driven method for in-treatment upper airway motion tracking using cine MRI in head and neck radiation therapy.

    Li, Hua; Chen, Hsin-Chen; Dolly, Steven; Li, Harold; Fischer-Valuck, Benjamin; Victoria, James; Dempsey, James; Ruan, Su; Anastasio, Mark; Mazur, Thomas; Gach, Michael; Kashani, Rojano; Green, Olga; Rodriguez, Vivian; Gay, Hiram; Thorstad, Wade; Mutic, Sasa

    2016-08-01

    For the first time, MRI-guided radiation therapy systems can acquire cine images to dynamically monitor in-treatment internal organ motion. However, the complex head and neck (H&N) structures and low-contrast/resolution of on-board cine MRI images make automatic motion tracking a very challenging task. In this study, the authors proposed an integrated model-driven method to automatically track the in-treatment motion of the H&N upper airway, a complex and highly deformable region wherein internal motion often occurs in an either voluntary or involuntary manner, from cine MRI images for the analysis of H&N motion patterns. Considering the complex H&N structures and ensuring automatic and robust upper airway motion tracking, the authors firstly built a set of linked statistical shapes (including face, face-jaw, and face-jaw-palate) using principal component analysis from clinically approved contours delineated on a set of training data. The linked statistical shapes integrate explicit landmarks and implicit shape representation. Then, a hierarchical model-fitting algorithm was developed to align the linked shapes on the first image frame of a to-be-tracked cine sequence and to localize the upper airway region. Finally, a multifeature level set contour propagation scheme was performed to identify the upper airway shape change, frame-by-frame, on the entire image sequence. The multifeature fitting energy, including the information of intensity variations, edge saliency, curve geometry, and temporal shape continuity, was minimized to capture the details of moving airway boundaries. Sagittal cine MR image sequences acquired from three H&N cancer patients were utilized to demonstrate the performance of the proposed motion tracking method. The tracking accuracy was validated by comparing the results to the average of two manual delineations in 50 randomly selected cine image frames from each patient. The resulting average dice similarity coefficient (93.28%  ±  1

  5. An integrated model-driven method for in-treatment upper airway motion tracking using cine MRI in head and neck radiation therapy

    Li, Hua, E-mail: huli@radonc.wustl.edu; Chen, Hsin-Chen; Dolly, Steven; Li, Harold; Fischer-Valuck, Benjamin; Mazur, Thomas; Gach, Michael; Kashani, Rojano; Green, Olga; Rodriguez, Vivian; Gay, Hiram; Thorstad, Wade; Mutic, Sasa [Department of Radiation Oncology, Washington University, St. Louis, Missouri 63110 (United States); Victoria, James; Dempsey, James [ViewRay Incorporated, Inc., Oakwood Village, Ohio 44146 (United States); Ruan, Su [Laboratoire LITIS (EA 4108), Equipe Quantif, University of Rouen, Rouen 76183 (France); Anastasio, Mark [Department of Biomedical Engineering, Washington University, St. Louis, Missouri 63110 (United States)

    2016-08-15

    Purpose: For the first time, MRI-guided radiation therapy systems can acquire cine images to dynamically monitor in-treatment internal organ motion. However, the complex head and neck (H&N) structures and low-contrast/resolution of on-board cine MRI images make automatic motion tracking a very challenging task. In this study, the authors proposed an integrated model-driven method to automatically track the in-treatment motion of the H&N upper airway, a complex and highly deformable region wherein internal motion often occurs in an either voluntary or involuntary manner, from cine MRI images for the analysis of H&N motion patterns. Methods: Considering the complex H&N structures and ensuring automatic and robust upper airway motion tracking, the authors firstly built a set of linked statistical shapes (including face, face-jaw, and face-jaw-palate) using principal component analysis from clinically approved contours delineated on a set of training data. The linked statistical shapes integrate explicit landmarks and implicit shape representation. Then, a hierarchical model-fitting algorithm was developed to align the linked shapes on the first image frame of a to-be-tracked cine sequence and to localize the upper airway region. Finally, a multifeature level set contour propagation scheme was performed to identify the upper airway shape change, frame-by-frame, on the entire image sequence. The multifeature fitting energy, including the information of intensity variations, edge saliency, curve geometry, and temporal shape continuity, was minimized to capture the details of moving airway boundaries. Sagittal cine MR image sequences acquired from three H&N cancer patients were utilized to demonstrate the performance of the proposed motion tracking method. Results: The tracking accuracy was validated by comparing the results to the average of two manual delineations in 50 randomly selected cine image frames from each patient. The resulting average dice similarity

  6. An integrated model-driven method for in-treatment upper airway motion tracking using cine MRI in head and neck radiation therapy

    Li, Hua; Chen, Hsin-Chen; Dolly, Steven; Li, Harold; Fischer-Valuck, Benjamin; Mazur, Thomas; Gach, Michael; Kashani, Rojano; Green, Olga; Rodriguez, Vivian; Gay, Hiram; Thorstad, Wade; Mutic, Sasa; Victoria, James; Dempsey, James; Ruan, Su; Anastasio, Mark

    2016-01-01

    Purpose: For the first time, MRI-guided radiation therapy systems can acquire cine images to dynamically monitor in-treatment internal organ motion. However, the complex head and neck (H&N) structures and low-contrast/resolution of on-board cine MRI images make automatic motion tracking a very challenging task. In this study, the authors proposed an integrated model-driven method to automatically track the in-treatment motion of the H&N upper airway, a complex and highly deformable region wherein internal motion often occurs in an either voluntary or involuntary manner, from cine MRI images for the analysis of H&N motion patterns. Methods: Considering the complex H&N structures and ensuring automatic and robust upper airway motion tracking, the authors firstly built a set of linked statistical shapes (including face, face-jaw, and face-jaw-palate) using principal component analysis from clinically approved contours delineated on a set of training data. The linked statistical shapes integrate explicit landmarks and implicit shape representation. Then, a hierarchical model-fitting algorithm was developed to align the linked shapes on the first image frame of a to-be-tracked cine sequence and to localize the upper airway region. Finally, a multifeature level set contour propagation scheme was performed to identify the upper airway shape change, frame-by-frame, on the entire image sequence. The multifeature fitting energy, including the information of intensity variations, edge saliency, curve geometry, and temporal shape continuity, was minimized to capture the details of moving airway boundaries. Sagittal cine MR image sequences acquired from three H&N cancer patients were utilized to demonstrate the performance of the proposed motion tracking method. Results: The tracking accuracy was validated by comparing the results to the average of two manual delineations in 50 randomly selected cine image frames from each patient. The resulting average dice similarity

  7. Integrating remote sensing, geographic information systems and global positioning system techniques with hydrological modeling

    Thakur, Jay Krishna; Singh, Sudhir Kumar; Ekanthalu, Vicky Shettigondahalli

    2017-07-01

    Integration of remote sensing (RS), geographic information systems (GIS) and global positioning system (GPS) are emerging research areas in the field of groundwater hydrology, resource management, environmental monitoring and during emergency response. Recent advancements in the fields of RS, GIS, GPS and higher level of computation will help in providing and handling a range of data simultaneously in a time- and cost-efficient manner. This review paper deals with hydrological modeling, uses of remote sensing and GIS in hydrological modeling, models of integrations and their need and in last the conclusion. After dealing with these issues conceptually and technically, we can develop better methods and novel approaches to handle large data sets and in a better way to communicate information related with rapidly decreasing societal resources, i.e. groundwater.

  8. Integration of Biodiversity Databases in Taiwan and Linkage to Global Databases

    Kwang-Tsao Shao

    2007-03-01

    Full Text Available The biodiversity databases in Taiwan were dispersed to various institutions and colleges with limited amount of data by 2001. The Natural Resources and Ecology GIS Database sponsored by the Council of Agriculture, which is part of the National Geographic Information System planned by the Ministry of Interior, was the most well established biodiversity database in Taiwan. But thisThis database was, however, mainly collectingcollected the distribution data of terrestrial animals and plants within the Taiwan area. In 2001, GBIF was formed, and Taiwan joined as one of the an Associate Participant and started, starting the establishment and integration of animal and plant species databases; therefore, TaiBIF was able to co-operate with GBIF. The information of Catalog of Life, specimens, and alien species were integrated by the Darwin core. The standard. These metadata standards allowed the biodiversity information of Taiwan to connect with global databases.

  9. A Short Tutorial on Inertial Navigation System and Global Positioning System Integration

    Smalling, Kyle M.; Eure, Kenneth W.

    2015-01-01

    The purpose of this document is to describe a simple method of integrating Inertial Navigation System (INS) information with Global Positioning System (GPS) information for an improved estimate of vehicle attitude and position. A simple two dimensional (2D) case is considered. The attitude estimates are derived from sensor data and used in the estimation of vehicle position and velocity through dead reckoning within the INS. The INS estimates are updated with GPS estimates using a Kalman filter. This tutorial is intended for the novice user with a focus on bringing the reader from raw sensor measurements to an integrated position and attitude estimate. An application is given using a remotely controlled ground vehicle operating in assumed 2D environment. The theory is developed first followed by an illustrative example.

  10. Business integration unit (BIU adapter for industrial global value chain on the web

    Adel Ghannam

    2016-05-01

    Full Text Available Today's manufacturing enterprises rarely live in isolation. They need to be connected in order to create products from which a group of enterprises, called global-value-chain (GVC, can derive value. Service-oriented architecture (SOA and event-driven architecture (EDA are two different paradigms that address complex integration challenges. Enterprise service bus (ESB allows for the implementation of both the SOA and the EDA concepts. This paper addresses the development of an enterprise service bus (ESB to grant the operation of GVC. A proposed business-integrator-unit (BIU is designed to be plugged in each enterprise system. The BIU contains a “business collaboration map configurator” that allows real time allocation of roles to members’ enterprises.

  11. Rolling Shutter Motion Deblurring

    Su, Shuochen

    2015-06-07

    Although motion blur and rolling shutter deformations are closely coupled artifacts in images taken with CMOS image sensors, the two phenomena have so far mostly been treated separately, with deblurring algorithms being unable to handle rolling shutter wobble, and rolling shutter algorithms being incapable of dealing with motion blur. We propose an approach that delivers sharp and undis torted output given a single rolling shutter motion blurred image. The key to achieving this is a global modeling of the camera motion trajectory, which enables each scanline of the image to be deblurred with the corresponding motion segment. We show the results of the proposed framework through experiments on synthetic and real data.

  12. Integration of Molecular Pathology, Epidemiology, and Social Science for Global Precision Medicine

    Nishi, Akihiro; Milner, Danny A; Giovannucci, Edward L.; Nishihara, Reiko; Tan, Andy S.; Kawachi, Ichiro; Ogino, Shuji

    2015-01-01

    Summary The precision medicine concept and the unique disease principle imply that each patient has unique pathogenic processes resulting from heterogeneous cellular genetic and epigenetic alterations, and interactions between cells (including immune cells) and exposures, including dietary, environmental, microbial, and lifestyle factors. As a core method field in population health science and medicine, epidemiology is a growing scientific discipline that can analyze disease risk factors, and develop statistical methodologies to maximize utilization of big data on populations and disease pathology. The evolving transdisciplinary field of molecular pathological epidemiology (MPE) can advance biomedical and health research by linking exposures to molecular pathologic signatures, enhancing causal inference, and identifying potential biomarkers for clinical impact. The MPE approach can be applied to any diseases, although it has been most commonly used in neoplastic diseases (including breast, lung and colorectal cancers) because of availability of various molecular diagnostic tests. However, use of state-of-the-art genomic, epigenomic and other omic technologies and expensive drugs in modern healthcare systems increases racial, ethnic and socioeconomic disparities. To address this, we propose to integrate molecular pathology, epidemiology, and social science. Social epidemiology integrates the latter two fields. The integrative social MPE model can embrace sociology, economics and precision medicine, address global health disparities and inequalities, and elucidate biological effects of social environments, behaviors, and networks. We foresee advancements of molecular medicine, including molecular diagnostics, biomedical imaging, and targeted therapeutics, which should benefit individuals in a global population, by means of an interdisciplinary approach of integrative MPE and social health science. PMID:26636627

  13. Global collapse and J integral analysis for inner-diameter defected curved plates in tension

    Hertelé, Stijn; Verstraete, Matthias; Denys, Rudi; De Waele, Wim

    2013-01-01

    Reference stress equations are widely used to predict both the limit load and the J integral response of defected structures. Their validity is key to performing a safe assessment of structural integrity (plastic collapse and fracture). An analytical reference stress equation based upon global collapse has recently been developed for curved plates with a part-through defect located at the inner diameter surface. This equation predicts decreasing reference stress values as plate curvature increases. To qualify the predictions, the authors have performed a series of finite element analyses covering a wide range of possible geometries. This paper compares the numerically obtained limit loads and J integral responses with the analytical predictions of the reference stress equation. The finite element results generally confirm the decrease of reference stress with increasing plate curvature. Highly pronounced differences may occur between flat plates and slightly curved plates. Overall, the analytically predicted decrease in reference stress is overestimated for small defects but is representative for larger defects. -- Highlights: • A reference stress equation for inner-diameter defected curved plates in tension was developed earlier. • The equation predicts a lower reference stress as plate curvature increases. • The analytical predictions are validated through finite element analysis. • Collapse and J integral are insensitive to curvature for small defects. • For large defects, the analytically predicted trend is confirmed

  14. Chimeric β-Lactamases: Global Conservation of Parental Function and Fast Time-Scale Dynamics with Increased Slow Motions

    Clouthier, Christopher M.; Morin, Sébastien; Gobeil, Sophie M. C.; Doucet, Nicolas; Blanchet, Jonathan; Nguyen, Elisabeth; Gagné, Stéphane M.; Pelletier, Joelle N.

    2012-01-01

    Enzyme engineering has been facilitated by recombination of close homologues, followed by functional screening. In one such effort, chimeras of two class-A β-lactamases – TEM-1 and PSE-4 – were created according to structure-guided protein recombination and selected for their capacity to promote bacterial proliferation in the presence of ampicillin (Voigt et al., Nat. Struct. Biol. 2002 9:553). To provide a more detailed assessment of the effects of protein recombination on the structure and function of the resulting chimeric enzymes, we characterized a series of functional TEM-1/PSE-4 chimeras possessing between 17 and 92 substitutions relative to TEM-1 β-lactamase. Circular dichroism and thermal scanning fluorimetry revealed that the chimeras were generally well folded. Despite harbouring important sequence variation relative to either of the two ‘parental’ β-lactamases, the chimeric β-lactamases displayed substrate recognition spectra and reactivity similar to their most closely-related parent. To gain further insight into the changes induced by chimerization, the chimera with 17 substitutions was investigated by NMR spin relaxation. While high order was conserved on the ps-ns timescale, a hallmark of class A β-lactamases, evidence of additional slow motions on the µs-ms timescale was extracted from model-free calculations. This is consistent with the greater number of resonances that could not be assigned in this chimera relative to the parental β-lactamases, and is consistent with this well-folded and functional chimeric β-lactamase displaying increased slow time-scale motions. PMID:23284969

  15. Ultra-Fine Scale Spatially-Integrated Mapping of Habitat and Occupancy Using Structure-From-Motion.

    Philip McDowall

    Full Text Available Organisms respond to and often simultaneously modify their environment. While these interactions are apparent at the landscape extent, the driving mechanisms often occur at very fine spatial scales. Structure-from-Motion (SfM, a computer vision technique, allows the simultaneous mapping of organisms and fine scale habitat, and will greatly improve our understanding of habitat suitability, ecophysiology, and the bi-directional relationship between geomorphology and habitat use. SfM can be used to create high-resolution (centimeter-scale three-dimensional (3D habitat models at low cost. These models can capture the abiotic conditions formed by terrain and simultaneously record the position of individual organisms within that terrain. While coloniality is common in seabird species, we have a poor understanding of the extent to which dense breeding aggregations are driven by fine-scale active aggregation or limited suitable habitat. We demonstrate the use of SfM for fine-scale habitat suitability by reconstructing the locations of nests in a gentoo penguin colony and fitting models that explicitly account for conspecific attraction. The resulting digital elevation models (DEMs are used as covariates in an inhomogeneous hybrid point process model. We find that gentoo penguin nest site selection is a function of the topography of the landscape, but that nests are far more aggregated than would be expected based on terrain alone, suggesting a strong role of behavioral aggregation in driving coloniality in this species. This integrated mapping of organisms and fine scale habitat will greatly improve our understanding of fine-scale habitat suitability, ecophysiology, and the complex bi-directional relationship between geomorphology and habitat use.

  16. A time-motion study of cardiovascular disease risk factor screening integrated into HIV clinic visits in Swaziland.

    Palma, Anton M; Rabkin, Miriam; Simelane, Samkelo; Gachuhi, Averie B; McNairy, Margaret L; Nuwagaba-Biribonwoha, Harriet; Bongomin, Pido; Okello, Velephi N; Bitchong, Raymond A; El-Sadr, Wafaa M

    2018-03-01

    Screening of modifiable cardiovascular disease (CVD) risk factors is recommended but not routinely provided for HIV-infected patients, especially in low-resource settings. Potential concerns include limited staff time and low patient acceptability, but little empirical data exists. As part of a pilot study of screening in a large urban HIV clinic in Swaziland, we conducted a time-motion study to assess the impact of screening on patient flow and HIV service delivery and exit interviews to assess patient acceptability. A convenience sample of patients ≥40 years of age attending routine HIV clinic visits was screened for hypertension, diabetes, hyperlipidemia and tobacco smoking. We observed HIV visits with and without screening and measured time spent on HIV and CVD risk factor screening activities. We compared screened and unscreened patients on total visit time and time spent receiving HIV services using Wilcoxon rank-sum tests. A separate convenience sample of screened patients participated in exit interviews to assess their satisfaction with screening. We observed 172 patient visits (122 with CVD risk factor screening and 50 without). Screening increased total visit time from a median (range) of 4 minutes (2 to 11) to 15 minutes (9 to 30) (p < 0.01). Time spent on HIV care was not affected: 4 (2 to 10) versus 4 (2 to 11) (p = 0.57). We recruited 126 patients for exit interviews, all of whom indicated that they would recommend screening to others. Provision of CVD risk factor screening more than tripled the length of routine HIV clinic visits but did not reduce the time spent on HIV services. Programme managers need to take longer visit duration into account in order to effectively integrate CVD risk factor screening and counselling into HIV programmes. © 2018 The Authors. Journal of the International AIDS Society published by John Wiley & sons Ltd on behalf of the International AIDS Society.

  17. The global Filipino nurse: An integrative review of Filipino nurses' work experiences.

    Montayre, Jed; Montayre, Jasmine; Holroyd, Eleanor

    2018-05-01

    To understand the work-related experiences of Philippine-trained nurses working globally. The Philippines is a major source country of foreign-trained nurses located globally. However, there is paucity of research on professional factors and career related issues affecting foreign-trained nurses' work experiences. An integrative review through a comprehensive search of literature was undertaken from November 2015 and was repeated in August 2016. Seven articles satisfied the selection criteria. Filipino nurses experienced differences in the practice of nursing in terms of work process, roles and autonomy. Moreover, they encountered challenges such as work-related discrimination and technical difficulties within the organisation. A clear understanding of Filipino nurses' work experiences and the challenges they have encountered suggests identification of important constructs influencing effective translation of nursing practice across cultures and health systems, which then form the basis for support strategies. It is critical to recognize foreign-trained nurses' experience of work-related differences and challenges as these foster favorable conditions for the management team to plan and continually evaluate policies around recruitment, retention and support offered to these nurses. Furthermore, findings suggest internationalization of nursing framework and standards integrating a transcultural paradigm among staff members within a work organisation. © 2017 John Wiley & Sons Ltd.

  18. Dynamics of global vegetation biomass simulated by the integrated Earth System Model

    Mao, J.; Shi, X.; Di Vittorio, A. V.; Thornton, P. E.; Piao, S.; Yang, X.; Truesdale, J. E.; Bond-Lamberty, B. P.; Chini, L. P.; Thomson, A. M.; Hurtt, G. C.; Collins, W.; Edmonds, J.

    2014-12-01

    The global vegetation biomass stores huge amounts of carbon and is thus important to the global carbon budget (Pan et al., 2010). For the past few decades, different observation-based estimates and modeling of biomass in the above- and below-ground vegetation compartments have been comprehensively conducted (Saatchi et al., 2011; Baccini et al., 2012). However, uncertainties still exist, in particular for the simulation of biomass magnitude, tendency, and the response of biomass to climatic conditions and natural and human disturbances. The recently successful coupling of the integrated Earth System Model (iESM) (Di Vittorio et al., 2014; Bond-Lamberty et al., 2014), which links the Global Change Assessment Model (GCAM), Global Land-use Model (GLM), and Community Earth System Model (CESM), offers a great opportunity to understand the biomass-related dynamics in a fully-coupled natural and human modeling system. In this study, we focus on the systematic analysis and evaluation of the iESM simulated historical (1850-2005) and future (2006-2100) biomass changes and the response of the biomass dynamics to various impact factors, in particular the human-induced Land Use/Land Cover Change (LULCC). By analyzing the iESM simulations with and without the interactive LULCC feedbacks, we further study how and where the climate feedbacks affect socioeconomic decisions and LULCC, such as to alter vegetation carbon storage. References Pan Y et. al: A large and persistent carbon sink in the World's forests. Science 2011, 333:988-993. Saatchi SS et al: Benchmark map of forest carbon stocks in tropical regions across three continents. Proc Natl Acad Sci 2011, 108:9899-9904. Baccini A et al: Estimated carbon dioxide emissions from tropical deforestation improved by carbon-density maps. Nature Clim Change 2012, 2:182-185. Di Vittorio AV et al: From land use to land cover: restoring the afforestation signal in a coupled integrated assessment-earth system model and the implications for

  19. On the integration developmental characteristics as a form of international policy in the context of modern globalization processes

    Bostan Sergii Ivanovich

    2014-12-01

    Full Text Available Under globalization of the world community, there are new opportunities and potential threats to the current system of international relations, collective security and geopolitical development of different regions. Integration and regionalization, consolidation and separatism entered upon the agenda of the political present. The integration process becomes one of the variations of peaceful and mutually beneficial solution to the question of the globalization influence of uneven development of the world regions, the fight against global problems of humanity, discrimination and intolerance, spread the values of democracy, rights, freedom and equality.

  20. Integrating NASA Earth Science Enterprise (ESE) Data Into Global Agricultural Decision Support Systems

    Teng, W.; Kempler, S.; Chiu, L.; Doraiswamy, P.; Liu, Z.; Milich, L.; Tetrault, R.

    2003-12-01

    Monitoring global agricultural crop conditions during the growing season and estimating potential seasonal production are critically important for market development of U.S. agricultural products and for global food security. Two major operational users of satellite remote sensing for global crop monitoring are the USDA Foreign Agricultural Service (FAS) and the U.N. World Food Programme (WFP). The primary goal of FAS is to improve foreign market access for U.S. agricultural products. The WFP uses food to meet emergency needs and to support economic and social development. Both use global agricultural decision support systems that can integrate and synthesize a variety of data sources to provide accurate and timely information on global crop conditions. The Goddard Space Flight Center Earth Sciences Distributed Active Archive Center (GES DAAC) has begun a project to provide operational solutions to FAS and WFP, by fully leveraging results from previous work, as well as from existing capabilities of the users. The GES DAAC has effectively used its recently developed prototype TRMM Online Visualization and Analysis System (TOVAS) to provide ESE data and information to the WFP for its agricultural drought monitoring efforts. This prototype system will be evolved into an Agricultural Information System (AIS), which will operationally provide ESE and other data products (e.g., rainfall, land productivity) and services, to be integrated into and thus enhance the existing GIS-based, decision support systems of FAS and WFP. Agriculture-oriented, ESE data products (e.g., MODIS-based, crop condition assessment product; TRMM derived, drought index product) will be input to a crop growth model in collaboration with the USDA Agricultural Research Service, to generate crop condition and yield prediction maps. The AIS will have the capability for remotely accessing distributed data, by being compliant with community-based interoperability standards, enabling easy access to

  1. Attention and apparent motion.

    Horowitz, T; Treisman, A

    1994-01-01

    Two dissociations between short- and long-range motion in visual search are reported. Previous research has shown parallel processing for short-range motion and apparently serial processing for long-range motion. This finding has been replicated and it has also been found that search for short-range targets can be impaired both by using bicontrast stimuli, and by prior adaptation to the target direction of motion. Neither factor impaired search in long-range motion displays. Adaptation actually facilitated search with long-range displays, which is attributed to response-level effects. A feature-integration account of apparent motion is proposed. In this theory, short-range motion depends on specialized motion feature detectors operating in parallel across the display, but subject to selective adaptation, whereas attention is needed to link successive elements when they appear at greater separations, or across opposite contrasts.

  2. An integrated model to simulate sown area changes for major crops at a global scale

    WU WenBin; YANG Peng; MENG ChaoYing; SHIBASAKI Ryosuke; ZHOU QingBo; TANG HuaJun; SHI Yun

    2008-01-01

    Dynamics of land use systems have attracted much attention from scientists around the world due to their ecological and socio-economic implications. An integrated model to dynamically simulate future changes in sown areas of four major crops (rice, maize, wheat and soybean) on a global scale is presented. To do so, a crop choice model was developed on the basis of Multinomial Logit (Logit) model to model land users' decisions on crop choices among a set of available alternatives with using a crop utility function. A GIS-based Environmental Policy Integrated Climate (EPIC) model was adopted to simulate the crop yields under a given geophysical environment and farming management conditions,while the International Food Policy and Agricultural Simulation (IFPSIM) model was utilized to estimate crop price in the international market. The crop choice model was linked with the GIS-based EPIC model and the IFPSIM model through data exchange. This integrated model was then validated against the FAO statistical data in 2001-2003 and the Moderate Resolution Imaging Spectroradiometer (MODIS)global land cover product in 2001. Both validation approaches indicated reliability of the model for addressing the dynamics in agricultural land use and its capability for long-term scenario analysis. Finally,the model application was designed to run over a time period of 30 a, taking the year 2000 as baseline.The model outcomes can help understand and explain the causes, locations and consequences of land use changes, and provide support for land use planning and policy making.

  3. An Improved Global Wind Resource Estimate for Integrated Assessment Models: Preprint

    Eurek, Kelly [National Renewable Energy Lab. (NREL), Golden, CO (United States); Sullivan, Patrick [National Renewable Energy Lab. (NREL), Golden, CO (United States); Gleason, Michael [National Renewable Energy Lab. (NREL), Golden, CO (United States); Hettinger, Dylan [National Renewable Energy Lab. (NREL), Golden, CO (United States); Heimiller, Donna [National Renewable Energy Lab. (NREL), Golden, CO (United States); Lopez, Anthony [National Renewable Energy Lab. (NREL), Golden, CO (United States)

    2017-02-01

    This paper summarizes initial steps to improving the robustness and accuracy of global renewable resource and techno-economic assessments for use in integrated assessment models. We outline a method to construct country-level wind resource supply curves, delineated by resource quality and other parameters. Using mesoscale reanalysis data, we generate estimates for wind quality, both terrestrial and offshore, across the globe. Because not all land or water area is suitable for development, appropriate database layers provide exclusions to reduce the total resource to its technical potential. We expand upon estimates from related studies by: using a globally consistent data source of uniquely detailed wind speed characterizations; assuming a non-constant coefficient of performance for adjusting power curves for altitude; categorizing the distance from resource sites to the electric power grid; and characterizing offshore exclusions on the basis of sea ice concentrations. The product, then, is technical potential by country, classified by resource quality as determined by net capacity factor. Additional classifications dimensions are available, including distance to transmission networks for terrestrial wind and distance to shore and water depth for offshore. We estimate the total global wind generation potential of 560 PWh for terrestrial wind with 90% of resource classified as low-to-mid quality, and 315 PWh for offshore wind with 67% classified as mid-to-high quality. These estimates are based on 3.5 MW composite wind turbines with 90 m hub heights, 0.95 availability, 90% array efficiency, and 5 MW/km2 deployment density in non-excluded areas. We compare the underlying technical assumption and results with other global assessments.

  4. Integrating Unified Gravity Wave Physics into the NOAA Next Generation Global Prediction System

    Alpert, J. C.; Yudin, V.; Fuller-Rowell, T. J.; Akmaev, R. A.

    2017-12-01

    The Unified Gravity Wave Physics (UGWP) project for the Next Generation Global Prediction System (NGGPS) is a NOAA collaborative effort between the National Centers for Environmental Prediction (NCEP), Environemntal Modeling Center (EMC) and the University of Colorado, Cooperative Institute for Research in Environmental Sciences (CU-CIRES) to support upgrades and improvements of GW dynamics (resolved scales) and physics (sub-grid scales) in the NOAA Environmental Modeling System (NEMS)†. As envisioned the global climate, weather and space weather models of NEMS will substantially improve their predictions and forecasts with the resolution-sensitive (scale-aware) formulations planned under the UGWP framework for both orographic and non-stationary waves. In particular, the planned improvements for the Global Forecast System (GFS) model of NEMS are: calibration of model physics for higher vertical and horizontal resolution and an extended vertical range of simulations, upgrades to GW schemes, including the turbulent heating and eddy mixing due to wave dissipation and breaking, and representation of the internally-generated QBO. The main priority of the UGWP project is unified parameterization of orographic and non-orographic GW effects including momentum deposition in the middle atmosphere and turbulent heating and eddies due to wave dissipation and breaking. The latter effects are not currently represented in NOAA atmosphere models. The team has tested and evaluated four candidate GW solvers integrating the selected GW schemes into the NGGPS model. Our current work and planned activity is to implement the UGWP schemes in the first available GFS/FV3 (open FV3) configuration including adapted GFDL modification for sub-grid orography in GFS. Initial global model results will be shown for the operational and research GFS configuration for spectral and FV3 dynamical cores. †http://www.emc.ncep.noaa.gov/index.php?branch=NEMS

  5. Reconciling uncertainties in integrated science and policy models: Applications to global climate change

    Kandlikar, Milind [Carnegie Mellon Univ., Pittsburgh, PA (United States)

    1994-12-01

    In this thesis tools of data reconciliation are used to integrate available information into scientific and policy models of greenhouse gases. The role of uncertainties in scientific and policy models of global climate change is examined, and implications for global change policy are drawn. Methane is the second most important greenhouse gas. Global sources and sinks of methane have significant uncertainties. A chance constrained methodology was developed and used to perform inversions on the global methane cycle. Budgets of methane that are consistent with source fluxes, isotopic and ice core measurements were determined. While it is not possible to come up with a single budget for CH{sub 4}, performing the calculation with a number of sets of assumed priors suggests a convergence in the allowed range for sources. In some cases -- wetlands (70-130 Tg/yr), rice paddies (60-125 Tg/yr) a significant reduction in the uncertainty of the source estimate is achieved. Our results compare favorably with the most recent measurements of flux estimates. For comparison, a similar analysis using bayes monte carlo simulation was performed. The question of the missing sink for carbon remains unresolved. Two analyses that attempt to quantify the missing sink were performed. First, a steady state analysis of the carbon cycle was used to determine the pre-industrial inter-hemispheric carbon concentration gradient. Second, a full blown dynamic inversion of the carbon cycle was performed. An advection diffusion ocean model with surface chemistry, coupled to box models of the atmosphere and the biosphere was inverted to fit available measurements of {sup 12}C and {sup 14}C carbon isotopes using Differential-Algebraic Optimization. The model effectively suggests that the {open_quotes}missing{close_quotes} sink for carbon is hiding in the biosphere. Scenario dependent trace gas indices were calculated for CH{sub 4}, N{sub 2}O, HCFC-22.

  6. Integrated modelling of anthropogenic land-use and land-cover change on the global scale

    Schaldach, R.; Koch, J.; Alcamo, J.

    2009-04-01

    In many cases land-use activities go hand in hand with substantial modifications of the physical and biological cover of the Earth's surface, resulting in direct effects on energy and matter fluxes between terrestrial ecosystems and the atmosphere. For instance, the conversion of forest to cropland is changing climate relevant surface parameters (e.g. albedo) as well as evapotranspiration processes and carbon flows. In turn, human land-use decisions are also influenced by environmental processes. Changing temperature and precipitation patterns for example are important determinants for location and intensity of agriculture. Due to these close linkages, processes of land-use and related land-cover change should be considered as important components in the construction of Earth System models. A major challenge in modelling land-use change on the global scale is the integration of socio-economic aspects and human decision making with environmental processes. One of the few global approaches that integrates functional components to represent both anthropogenic and environmental aspects of land-use change, is the LandSHIFT model. It simulates the spatial and temporal dynamics of the human land-use activities settlement, cultivation of food crops and grazing management, which compete for the available land resources. The rational of the model is to regionalize the demands for area intensive commodities (e.g. crop production) and services (e.g. space for housing) from the country-level to a global grid with the spatial resolution of 5 arc-minutes. The modelled land-use decisions within the agricultural sector are influenced by changing climate and the resulting effects on biomass productivity. Currently, this causal chain is modelled by integrating results from the process-based vegetation model LPJmL model for changing crop yields and net primary productivity of grazing land. Model output of LandSHIFT is a time series of grid maps with land-use/land-cover information

  7. Globalization

    Plum, Maja

    Globalization is often referred to as external to education - a state of affair facing the modern curriculum with numerous challenges. In this paper it is examined as internal to curriculum; analysed as a problematization in a Foucaultian sense. That is, as a complex of attentions, worries, ways...... of reasoning, producing curricular variables. The analysis is made through an example of early childhood curriculum in Danish Pre-school, and the way the curricular variable of the pre-school child comes into being through globalization as a problematization, carried forth by the comparative practices of PISA...

  8. Globalization

    F. Gerard Adams

    2008-01-01

    The rapid globalization of the world economy is causing fundamental changes in patterns of trade and finance. Some economists have argued that globalization has arrived and that the world is “flat†. While the geographic scope of markets has increased, the author argues that new patterns of trade and finance are a result of the discrepancies between “old†countries and “new†. As the differences are gradually wiped out, particularly if knowledge and technology spread worldwide, the t...

  9. Progress toward an Integrated Global Greenhouse Gas Information System (IG3IS)

    DeCola, P.; Butler, J. H.; Stanitski, D.; Tarasova, O. A.; Terblanche, D. E.; Duren, R. M.; Gurney, K. R.; Manning, A.; Reimann, S.; Ciais, P.; Arnold, T.; Burston, J.; Rayner, P. J.; Wofsy, S. C.; Hamburg, S.; Zavala-Araiza, D.; Miller, J. B.; Gerbig, C.; Vogel, F. R.; Canadell, J.

    2016-12-01

    Accurate and precise atmospheric long-term measurements of greenhouse gas (GHG) concentrations have revealed the rapid and unceasing rise of global GHG concentrations due to human socioeconomic activity. Long-term observations also show a resulting rise in global temperatures and evidence of negative impacts on society. In response to this mounting evidence, nations, sub-national governments, private enterprises and individuals are establishing and accelerating efforts to reduce GHG emissions while meeting the needs for global development and increasing energy access. With this motivation, WMO and its partners have called for an Integrated Global Greenhouse Information System (IG3IS). The IG3IS will serve as an international coordinating mechanism to establish and propagate consistent methods and standards to help assess emission-reduction actions. For the IG3IS initiative to succeed the end users must understand, trust, and recognize the value of the information they receive, and act more effectively in response. Over time, the IG3IS framework will be capable of promoting and accepting advancing technical capabilities (e.g., new satellite observations), continually improving the quality of and confidence in such information. By combining accurate atmospheric measurements with enhanced socioeconomic activity data and model analyses we can meet the overarching goals of IG3IS to: Reduce uncertainty of emission inventory reporting, Locate, quantify and prioritize previously unknown emission reduction opportunities, and Provide national and sub-national governments with timely and quantified information to support their assessment of progress towards their mitigation goals. An effective IG3IS will provide on-going, observation-based information on the relative success of GHG management efforts on policy-relevant scales and the response of the global carbon cycle to a warming world. The presentation will cover the principles and objectives of IG3IS, as well as progress

  10. The educated citizen and global public health issues: One model for integration into the undergraduate curriculum

    Rosemary M. Caron

    2016-03-01

    Full Text Available The Educated Citizen Initiative proposes that an understanding of public health issues is a core component of an educated citizenry and is essential to developing one’s societal responsibility. This initiative supports the Institute of Medicine’s recommendation that all undergraduates should have access to education in public health. Furthermore, the Liberal Education and America’s Promise (LEAP framework developed by the Association of American Colleges and Universities supports the integration of public health education into general and liberal education with an aim to produce an educated citizenry. The LEAP framework is implemented by teaching about the role of social determinants in a population’s health status; the significance of personal and social responsibility; and providing skills for inquiry, critical thinking, problem solving, and evaluation. This article describes one university’s experience in generating an educated citizenry cognizant of comprehensive public health conflicts, thus contributing to both a local and global perspective on learning.

  11. New Faces of Globalization: Market Integration, Production Disintegration, Genesis of New Global Organizational Structures for Production and Trade

    Sarmiza Pencea

    2010-01-01

    Due to trade liberalisation and ITC revolution, companies could imagine new and better ways of creating and delivering value. In search of higher efficiency, competitiveness and profits, they reorganise, choosing to focus on their core competencies and to globally outsource, or offshore non-core activities and functions. As a result, reorganisation and relocation became the new forces of change across economies, leading to the rise of new, more diverse and more efficient global organisational...

  12. Motion-corrected whole-heart PET-MR for the simultaneous visualisation of coronary artery integrity and myocardial viability: an initial clinical validation.

    Munoz, Camila; Kunze, Karl P; Neji, Radhouene; Vitadello, Teresa; Rischpler, Christoph; Botnar, René M; Nekolla, Stephan G; Prieto, Claudia

    2018-05-12

    Cardiac PET-MR has shown potential for the comprehensive assessment of coronary heart disease. However, image degradation due to physiological motion remains a challenge that could hinder the adoption of this technology in clinical practice. The purpose of this study was to validate a recently proposed respiratory motion-corrected PET-MR framework for the simultaneous visualisation of myocardial viability ( 18 F-FDG PET) and coronary artery anatomy (coronary MR angiography, CMRA) in patients with chronic total occlusion (CTO). A cohort of 14 patients was scanned with the proposed PET-CMRA framework. PET and CMRA images were reconstructed with and without the proposed motion correction approach for comparison purposes. Metrics of image quality including visible vessel length and sharpness were obtained for CMRA for both the right and left anterior descending coronary arteries (RCA, LAD), and relative increase in 18 F-FDG PET signal after motion correction for standard 17-segment polar maps was computed. Resulting coronary anatomy by CMRA and myocardial integrity by PET were visually compared against X-ray angiography and conventional Late Gadolinium Enhancement (LGE) MRI, respectively. Motion correction increased CMRA visible vessel length by 49.9% and 32.6% (RCA, LAD) and vessel sharpness by 12.3% and 18.9% (RCA, LAD) on average compared to uncorrected images. Coronary lumen delineation on motion-corrected CMRA images was in good agreement with X-ray angiography findings. For PET, motion correction resulted in an average 8% increase in 18 F-FDG signal in the inferior and inferolateral segments of the myocardial wall. An improved delineation of myocardial viability defects and reduced noise in the 18 F-FDG PET images was observed, improving correspondence to subendocardial LGE-MRI findings compared to uncorrected images. The feasibility of the PET-CMRA framework for simultaneous cardiac PET-MR imaging in a short and predictable scan time (~11 min) has been

  13. The global resource balance table, an integrated table of energy, materials and the environment

    Tsuchiya, Haruki

    2013-01-01

    This paper introduces the Global Resource Balance Table (GRBT), which is an extension of the energy balance tables that expresses the relationships between energy, materials and the environment. The material division of the GRBT includes steel, cement, paper, wood and grain. In contrast, the environmental division of the GRBT includes oxygen, CO 2 and methane. The transaction division rows in the GRBT include production, conversion, end use and stock. Each cell of the GRBT contains the quantities of the respective resources that were generated or consumed. The relationships between the cells were constructed from the laws of conservation of the materials and energy. We constructed a GRBT for 2007 and discussed the increasing air temperature due to waste heat and the CO 2 equivalent from human breathing. The GRBT is a comprehensive integrated table that represents the resources that are consumed by human activities and is useful for energy and environmental studies. - Highlights: • We extended energy balance table and introduced Global Resource Balance Table. • It shows relationships between energy, materials and the environment. • The material division includes steel, cement, paper, wood and grain. • The environmental division includes oxygen, CO 2 and methane. • We discussed on waste heat and CO 2 emission by human breathing

  14. Overview of IMAGE 2.0. An integrated model of climate change and the global environment

    Alcamo, J.; Battjes, C.; Van den Born, G.J.; Bouwman, A.F.; De Haan, B.J.; Klein Goldewijk, K.; Klepper, O.; Kreileman, G.J.J.; Krol, M.; Leemans, R.; Van Minnen, J.G.; Olivier, J.G.J.; De Vries, H.J.M.; Toet, A.M.C.; Van den Wijngaart, R.A.; Van der Woerd, H.J.; Zuidema, G.

    1995-01-01

    The IMAGE 2.0 model is a multi-disciplinary, integrated model, designed to simulate the dynamics of the global society-biosphere-climate system. In this paper the focus is on the scientific aspects of the model, while another paper in this volume emphasizes its political aspects. The objectives of IMAGE 2.0 are to investigate linkages and feedbacks in the global system, and to evaluate consequences of climate policies. Dynamic calculations are performed to the year 2100, with a spatial scale ranging from grid (0.5x0.5 latitude-longitude) to world political regions, depending on the sub-model. A total of 13 sub-models make up IMAGE 2.0, and they are organized into three fully linked sub-systems: Energy-Industry, Terrestrial Environment, and Atmosphere-Ocean. The fully linked model has been tested against data from 1970 to 1990, and after calibration it can reproduce the following observed trends: regional energy consumption and energy-related emissions, terrestrial flux of carbon dioxide and emissions of greenhouse gases, concentrations of greenhouse gases in the atmosphere, and transformation of land cover. The model can also simulate current zonal average surface and vertical temperatures. 1 fig., 10 refs

  15. Integrated and global pseudotargeted metabolomics strategy applied to screening for quality control markers of Citrus TCMs.

    Shu, Yisong; Liu, Zhenli; Zhao, Siyu; Song, Zhiqian; He, Dan; Wang, Menglei; Zeng, Honglian; Lu, Cheng; Lu, Aiping; Liu, Yuanyan

    2017-08-01

    Traditional Chinese medicine (TCM) exerts its therapeutic effect in a holistic fashion with the synergistic function of multiple characteristic constituents. The holism philosophy of TCM is coincident with global and systematic theories of metabolomics. The proposed pseudotargeted metabolomics methodologies were employed for the establishment of reliable quality control markers for use in the screening strategy of TCMs. Pseudotargeted metabolomics integrates the advantages of both targeted and untargeted methods. In the present study, targeted metabolomics equipped with the gold standard RRLC-QqQ-MS method was employed for in vivo quantitative plasma pharmacochemistry study of characteristic prototypic constituents. Meanwhile, untargeted metabolomics using UHPLC-QE Orbitrap HRMS with better specificity and selectivity was employed for identification of untargeted metabolites in the complex plasma matrix. In all, 32 prototypic metabolites were quantitatively determined, and 66 biotransformed metabolites were convincingly identified after being orally administered with standard extracts of four labeled Citrus TCMs. The global absorption and metabolism process of complex TCMs was depicted in a systematic manner.

  16. JOURNAL CLUB: Redefining the Radiology Curriculum in Medical School: Vertical Integration and Global Accessibility.

    Retrouvey, Michele; Trace, Anthony Paul; Goodmurphy, Craig W; Shaves, Sarah

    2018-01-01

    Radiology interconnects medical disciplines given that a working understanding of imaging is essential to clinicians of every specialty. Using online education, we created a globally accessible, web-based undergraduate medical radiology curriculum modeled after the National Medical Student Curriculum in Radiology program of the Alliance of Medical Student Educators in Radiology. Seventy-four radiology faculty-mentored video modules were produced, 50 of which were integrated into the 1st-year anatomy course. We administered tests to medical students before and after students saw the videos to assess the effectiveness of the modules. We surveyed students on their interests in pursuing radiology as a career before and after participating in this curriculum. On the preexamination questions, the mean score was 58.0%, which increased to 83.6% on the pair-matched imaging-related questions on the actual examination. Before participating in the new curriculum, 88% of students did not express an interest in radiology, and 9% were undecided about radiology as a future career. There was an increase in students who reported that they would definitely or most likely pursue a career in radiology (7%) after they had viewed the lectures. Radiology education is now available to a greater number of multidisciplinary learners worldwide. This project produced a comprehensive, globally accessible radiology curriculum in a self-paced, flexible learning format for new generations of physicians.

  17. Beyond Scientism and Skepticism: An Integrative Approach to Global Mental Health

    Dan J Stein

    2015-11-01

    Full Text Available The global burden of disorders has shifted from infectious disease to non-communicable diseases, including neuropsychiatric disorders. Whereas infectious disease can sometimes be combated by targeting single causal mechanisms, such as prevention of contact-spread illness by hand-washing, in the case of mental disorders multiple causal mechanisms are relevant. The emergent field of global mental health has emphasized the magnitude of the treatment gap, particularly in the low and middle income world, and has paid particular attention to upstream causal factors, for example, poverty, inequality, and gender discrimination in the pathogenesis of mental disorders. However, this field has also been criticised for relying on erroneous Western paradigms of mental illness, which may not be relevant or appropriate to the low- and middle-income context. Here, it is important to steer a path between scienticism and skepticism. Scientism regards mental disorders as essential categories, and takes a covering law approach to causality; skepticism regards mental disorders as merely social constructions, and emphasizes the role of political power in causal relations. We propose an integrative model that emphasizes the contribution of a broad range of causal mechanisms operating at biological and societal levels to mental disorders, and the consequent importance of broad-spectrum and multi-pronged approaches to intervention.

  18. The NIAID Division of AIDS enterprise information system: integrated decision support for global clinical research programs

    Gupta, Nitin; Varghese, Suresh; Virkar, Hemant

    2011-01-01

    The National Institute of Allergy and Infectious Diseases (NIAID) Division of AIDS (DAIDS) Enterprise Information System (DAIDS-ES) is a web-based system that supports NIAID in the scientific, strategic, and tactical management of its global clinical research programs for HIV/AIDS vaccines, prevention, and therapeutics. Different from most commercial clinical trials information systems, which are typically protocol-driven, the DAIDS-ES was built to exchange information with those types of systems and integrate it in ways that help scientific program directors lead the research effort and keep pace with the complex and ever-changing global HIV/AIDS pandemic. Whereas commercially available clinical trials support systems are not usually disease-focused, DAIDS-ES was specifically designed to capture and incorporate unique scientific, demographic, and logistical aspects of HIV/AIDS treatment, prevention, and vaccine research in order to provide a rich source of information to guide informed decision-making. Sharing data across its internal components and with external systems, using defined vocabularies, open standards and flexible interfaces, the DAIDS-ES enables NIAID, its global collaborators and stakeholders, access to timely, quality information about NIAID-supported clinical trials which is utilized to: (1) analyze the research portfolio, assess capacity, identify opportunities, and avoid redundancies; (2) help support study safety, quality, ethics, and regulatory compliance; (3) conduct evidence-based policy analysis and business process re-engineering for improved efficiency. This report summarizes how the DAIDS-ES was conceptualized, how it differs from typical clinical trial support systems, the rationale for key design choices, and examples of how it is being used to advance the efficiency and effectiveness of NIAID's HIV/AIDS clinical research programs. PMID:21816958

  19. Evaluation of POE and instructor-led problem-solving approaches integrated into force and motion lecture classes using a model analysis technique

    Rakkapao, S; Pengpan, T; Srikeaw, S; Prasitpong, S

    2014-01-01

    This study aims to investigate the use of the predict–observe–explain (POE) approach integrated into large lecture classes on forces and motion. It is compared to the instructor-led problem-solving method using model analysis. The samples are science (SC, N = 420) and engineering (EN, N = 434) freshmen, from Prince of Songkla University, Thailand. Research findings from the force and motion conceptual evaluation indicate that the multimedia-supported POE method promotes students’ learning better than the problem-solving method, in particular for the velocity and acceleration concepts. There is a small shift of the students’ model states after the problem-solving instruction. Moreover, by using model analysis instructors are able to investigate students’ misconceptions and evaluate teaching methods. It benefits instructors in organizing subsequent instructional materials. (paper)

  20. The WTO Agreement on government procurement as a tool for Ukraine’s integration into the global value chains

    GUZHVA IGOR

    2015-01-01

    The article deals with the features of modern internationalization of production and economic relations among economic entities around the world based on the global value chains formation. The essence and the basic provisions of the multilateral WTO Agreement on Government Procurement as the integration tool of Ukraine’s industries into the global value chains are revealed. The Ukraine’s government procurement reforming progress towards the relevant WTO rules and regulations full implementati...

  1. Integrating abundance and functional traits reveals new global hotspots of fish diversity.

    Stuart-Smith, Rick D; Bates, Amanda E; Lefcheck, Jonathan S; Duffy, J Emmett; Baker, Susan C; Thomson, Russell J; Stuart-Smith, Jemina F; Hill, Nicole A; Kininmonth, Stuart J; Airoldi, Laura; Becerro, Mikel A; Campbell, Stuart J; Dawson, Terence P; Navarrete, Sergio A; Soler, German A; Strain, Elisabeth M A; Willis, Trevor J; Edgar, Graham J

    2013-09-26

    Species richness has dominated our view of global biodiversity patterns for centuries. The dominance of this paradigm is reflected in the focus by ecologists and conservation managers on richness and associated occurrence-based measures for understanding drivers of broad-scale diversity patterns and as a biological basis for management. However, this is changing rapidly, as it is now recognized that not only the number of species but the species present, their phenotypes and the number of individuals of each species are critical in determining the nature and strength of the relationships between species diversity and a range of ecological functions (such as biomass production and nutrient cycling). Integrating these measures should provide a more relevant representation of global biodiversity patterns in terms of ecological functions than that provided by simple species counts. Here we provide comparisons of a traditional global biodiversity distribution measure based on richness with metrics that incorporate species abundances and functional traits. We use data from standardized quantitative surveys of 2,473 marine reef fish species at 1,844 sites, spanning 133 degrees of latitude from all ocean basins, to identify new diversity hotspots in some temperate regions and the tropical eastern Pacific Ocean. These relate to high diversity of functional traits amongst individuals in the community (calculated using Rao's Q), and differ from previously reported patterns in functional diversity and richness for terrestrial animals, which emphasize species-rich tropical regions only. There is a global trend for greater evenness in the number of individuals of each species, across the reef fish species observed at sites ('community evenness'), at higher latitudes. This contributes to the distribution of functional diversity hotspots and contrasts with well-known latitudinal gradients in richness. Our findings suggest that the contribution of species diversity to a range of

  2. The New Coordinates of Globalization and Regional Integration: Resizing the Euro-Mediterranean Partnership

    Marcel Moldoveanu

    2017-04-01

    Full Text Available The increasingly strong process of interdependence between globalization and regionalization - in the context of the end of the bipolar power at world level - has engendered a new philosophy regarding the evolution of the world, a reconsideration of the strategy of political and diplomatic, economic and also cultural and human relationships. In my opinion, in a multipolar world, that will bring into the first line of international relations new big actors of regional and universal vocation (China, Rusia, Brasil, India, the European Union will play an extensive role in participating at the geostrategic, regional and global equilibrium, through promotion of an „open diplomacy” that will allow – by dialogue and cooperation – the resolving more rapidly and efficiently the great challenges of the beginning of the century and millenium: the reduction of the great development gaps, the regional and global security, in a very solid economic background. A new dimension of the EU enlargement policy at regional scale is represented by the cooperation relations and the attraction into the European circuit of material and spiritual values of the countries in the Central and Eastern Europe. In the context of deepening the interdependence and complementarities at regional and global level, more focus should be put on the viable ways and modalities to intensify the cooperation in the Danube-Black Sea and Euro-Mediterranean geo-economic and strategic areas. The two big geo-strategic regions of the world belong to the same civilization and are subject to similar changes as the other regions of the world, despite some specific features of history and culture. The intensification and diversification of the cooperation at the Central and South-Eastern European level, as well as the Euro-Mediterranean and Danube-Black Sea region, does not represent an alternative to the general objective process of integration into the Euro-Atlantic structures, but a

  3. Progress toward an Integrated Global GHG Information System (IG3IS)

    DeCola, Philip

    2016-04-01

    from a specific human activity. Based upon the recent advances in GHG observation technologies, new data-mining tools for acquiring socioeconomic activity data, and enhancements to the computational models used to merge this data, WMO and its partners are developing a plan for an Integrated Global GHG Information System (IG3IS) able to evaluate the efficacy of policy, reduce emission inventory uncertainty, and inform additional mitigation actions. The presentation will cover the principles and objectives of IG3IS, as well as progress toward answering the questions: What research capabilities are ready and able to deliver useful information for whom? What decisions will be informed? What valuable and additional outcomes will result?

  4. Ground motion attenuation during M 7.1 Darfield and M 6.2 Christchurch, New Zealand, earthquakes and performance of global Ppedictive models

    Segou, Margaret; Kalkan, Erol

    2011-01-01

    The M 7.1 Darfield earthquake occurred 40 km west of Christchurch (New Zealand) on 4 September 2010. Six months after, the city was struck again with an M 6.2 event on 22 February local time (21 February UTC). These events resulted in significant damage to infrastructure in the city and its suburbs. The purpose of this study is to evaluate the performance of global predictive models (GMPEs) using the strong motion data obtained from these two events to improve future seismic hazard assessment and building code provisions for the Canterbury region.The Canterbury region is located on the boundary between the Pacific and Australian plates; its surface expression is the active right lateral Alpine fault (Berryman et al. 1993). Beneath the North Island and the north South Island, the Pacific plate subducts obliquely under the Australian plate, while at the southwestern part of the South Island, a reverse process takes place. Although New Zealand has experienced several major earthquakes in the past as a result of its complex seismotectonic environment (e.g., M 7.1 1888 North Canterbury, M 7.0 1929 Arthur's Pass, and M 6.2 1995 Cass), there was no evidence of prior seismic activity in Christchurch and its surroundings before the September event. The Darfield and Christchurch earthquakes occurred along the previously unmapped Greendale fault in the Canterbury basin, which is covered by Quaternary alluvial deposits (Forsyth et al. 2008). In Figure 1, site conditions of the Canterbury epicentral area are depicted on a VS30 map. This map was determined on the basis of topographic slope calculated from a 1-km grid using the method of Allen and Wald (2007). Also shown are the locations of strong motion stations.The Darfield event was generated as a result of a complex rupture mechanism; the recordings and geodetic data reveal that earthquake consists of three sub-events (Barnhart et al. 2011, page 815 of this issue). The first event was due to rupturing of a blind reverse

  5. The integration of object levels and their content: a theory of global/local processing and related hemispheric differences.

    Hübner, Ronald; Volberg, Gregor

    2005-06-01

    This article presents and tests the authors' integration hypothesis of global/local processing, which proposes that at early stages of processing, the identities of global and local units of a hierarchical stimulus are represented separately from information about their respective levels and that, therefore, identity and level information have to be integrated at later stages. It further states that the cerebral hemispheres differ in their capacities for these binding processes. Three experiments are reported in which the integration hypothesis was tested. Participants had to identify a letter at a prespecified level with the viewing duration restricted by a mask. False reporting of the letter at the nontarget level was predicted to occur more often when the integration of identity and level could fail. This was the case. Moreover, visual-field effects occurred, as expected. Finally, a multinomial model was constructed and fitted to the data. ((c) 2005 APA, all rights reserved).

  6. New Faces of Globalization: Market Integration, Production Disintegration, Genesis of New Global Organizational Structures for Production and Trade

    Sarmiza Pencea

    2010-07-01

    Full Text Available Due to trade liberalisation and ITC revolution, companies could imagine new and better ways of creating and delivering value. In search of higher efficiency, competitiveness and profits, they reorganise, choosing to focus on their core competencies and to globally outsource, or offshore non-core activities and functions. As a result, reorganisation and relocation became the new forces of change across economies, leading to the rise of new, more diverse and more efficient global organisational structures for investment, production and trade. A number of developing countries with adequate comparative advantages could better benefit from these processes, accelerating their own industralization and modernization, increasing their access to new technologies and managerial know-how and turning themselves into successful, high-rate growing, „ emerging” economies. The paper concludes that under such a global backdrop, taking part in global value chains (GVC and in international production networks (IPNs could be the best strategic option for both company strategies and governmental catch-up policies, provided that, or especially if companies enjoy high competences and tacit skills which make them capable of assuming complex tasks and of climbing further the technological ladder.

  7. Integrated Collaborative E-Learning for the Global Management Education in the 21st Century

    Son, Barbara W. K.

    2017-01-01

    Rapidly growing information and communications technology and a more interconnected global world offer benefits and challenges to global business organizations. While exploring benefits from global workforce and global production, they must successfully adapt to their local market conditions and manage their multicultural resources. How can we…

  8. Quantifying biological integrity by taxonomic completeness: its utility in regional and global assessments.

    Hawkins, Charles P

    2006-08-01

    Water resources managers and conservation biologists need reliable, quantitative, and directly comparable methods for assessing the biological integrity of the world's aquatic ecosystems. Large-scale assessments are constrained by the lack of consistency in the indicators used to assess biological integrity and our current inability to translate between indicators. In theory, assessments based on estimates of taxonomic completeness, i.e., the proportion of expected taxa that were observed (observed/expected, O/E) are directly comparable to one another and should therefore allow regionally and globally consistent summaries of the biological integrity of freshwater ecosystems. However, we know little about the true comparability of O/E assessments derived from different data sets or how well O/E assessments perform relative to other indicators in use. I compared the performance (precision, bias, and sensitivity to stressors) of O/E assessments based on five different data sets with the performance of the indicators previously applied to these data (three multimetric indices, a biotic index, and a hybrid method used by the state of Maine). Analyses were based on data collected from U.S. stream ecosystems in North Carolina, the Mid-Atlantic Highlands, Maine, and Ohio. O/E assessments resulted in very similar estimates of mean regional conditions compared with most other indicators once these indicators' values were standardized relative to reference-site means. However, other indicators tended to be biased estimators of O/E, a consequence of differences in their response to natural environmental gradients and sensitivity to stressors. These results imply that, in some cases, it may be possible to compare assessments derived from different indicators by standardizing their values (a statistical approach to data harmonization). In situations where it is difficult to standardize or otherwise harmonize two or more indicators, O/E values can easily be derived from existing

  9. Decarbonizing the Global Economy - An Integrated Assessment of Low Carbon Emission Scenarios proposed in Climate Policy

    Hokamp, Sascha; Khabbazan, Mohammad Mohammadi

    2017-04-01

    In 2015, the Conference of the Parties (COP 21) reaffirmed to targeting the global mean temperature rise below 2 °C in 2100 while finding no consent on decarbonizing the global economy, and instead, the final agreement called for enhanced scientific investigation of low carbon emission scenarios (UNFCC, 2015). In addition, the Climate Action Network International (CAN) proposes Special Reports to address decarbonization and low carbon development including 1.5 °C scenarios (IPCC, 2016). In response to these developments, we investigate whether the carbon emission cuts, in accordance with the recent climate policy proposals, may reach the climate target. To tackle this research question, we employ the coupled climate-energy-economy integrated assessment Model of INvestment and endogenous technological Development (MIND, cf. Edenhofer et al., 2005, Neubersch et al. 2014). Extending MIND's climate module to the two-box version used in the Dynamic Integrated model of Climate and the Economy (DICE, cf. Nordhaus and Sztorc, 2013, Nordhaus 2014), we perform a cost-effectiveness analysis with constraints on anthropogenic carbon emissions. We show that a climate policy scenario with early decarbonization complies with the 2° C climate target, even without Carbon Capturing and Storage (CCS) or negative emissions (see van Vuuren et al., 2013, for negative emissions). However, using emission inertia of 3.7 percent annually, reflecting the inflexibility on transforming the energy sector, we find a climate policy with moderately low emissions from 2100 onwards at a cost in terms of Balanced Growth Equivalents (BGE, cf. Anthoff and Tol, 2009) of 0.764 % that requires an early (2035 vs. 2120) peak of investments in renewable energy production compared to a business-as-usual scenario. Hence, decarbonizing the global economy and achieving the 2 °C target might still be possible before 2100, but the window of opportunity is beginning to close. References: Anthoff, D., and Tol, R

  10. An integrated approach for estimating global glacio isostatic adjustment, land ice, hydrology and ocean mass trends within a complete coupled Earth system framework

    Schumacher, M.; Bamber, J. L.; Martin, A.

    2016-12-01

    Future sea level rise (SLR) is one of the most serious consequences of climate change. Therefore, understanding the drivers of past sea level change is crucial for improving predictions. SLR integrates many Earth system components including oceans, land ice, terrestrial water storage, as well as solid Earth effects. Traditionally, each component have been tackled separately, which has often lead to inconsistencies between discipline-specific estimates of each part of the sea level budget. To address these issues, the European Research Council has funded a five year project aimed at producing a physically-based, data-driven solution for the complete coupled land-ocean-solid Earth system that is consistent with the full suite of observations, prior knowledge and fundamental geophysical constraints. The project is called "GlobalMass" and based at University of Bristol. Observed mass movement from the GRACE mission plus vertical land motion from a global network of permanent GPS stations will be utilized in a data-driven approach to estimate glacial isostatic adjustment (GIA) without introducing any assumptions about the Earth structure or ice loading history. A Bayesian Hierarchical Model (BHM) will be used as the framework to combine the satellite and in-situ observations alongside prior information that incorporates the physics of the coupled system such as conservation of mass and characteristic length scales of different processes in both space and time. The BHM is used to implement a simultaneous solution at a global scale. It will produce a consistent partitioning of the integrated SLR signal into its steric (thermal) and barystatic (mass) component for the satellite era. The latter component is induced by hydrological mass trends and melting of land ice. The BHM was developed and tested on Antarctica, where it has been used to separate surface, ice dynamic and GIA signals simultaneously. We illustrate the approach and concepts with examples from this test case

  11. GLOFRIM v1.0 - A globally applicable computational framework for integrated hydrological-hydrodynamic modelling

    Hoch, Jannis M.; Neal, Jeffrey C.; Baart, Fedor; van Beek, Rens; Winsemius, Hessel C.; Bates, Paul D.; Bierkens, Marc F. P.

    2017-10-01

    We here present GLOFRIM, a globally applicable computational framework for integrated hydrological-hydrodynamic modelling. GLOFRIM facilitates spatially explicit coupling of hydrodynamic and hydrologic models and caters for an ensemble of models to be coupled. It currently encompasses the global hydrological model PCR-GLOBWB as well as the hydrodynamic models Delft3D Flexible Mesh (DFM; solving the full shallow-water equations and allowing for spatially flexible meshing) and LISFLOOD-FP (LFP; solving the local inertia equations and running on regular grids). The main advantages of the framework are its open and free access, its global applicability, its versatility, and its extensibility with other hydrological or hydrodynamic models. Before applying GLOFRIM to an actual test case, we benchmarked both DFM and LFP for a synthetic test case. Results show that for sub-critical flow conditions, discharge response to the same input signal is near-identical for both models, which agrees with previous studies. We subsequently applied the framework to the Amazon River basin to not only test the framework thoroughly, but also to perform a first-ever benchmark of flexible and regular grids on a large-scale. Both DFM and LFP produce comparable results in terms of simulated discharge with LFP exhibiting slightly higher accuracy as expressed by a Kling-Gupta efficiency of 0.82 compared to 0.76 for DFM. However, benchmarking inundation extent between DFM and LFP over the entire study area, a critical success index of 0.46 was obtained, indicating that the models disagree as often as they agree. Differences between models in both simulated discharge and inundation extent are to a large extent attributable to the gridding techniques employed. In fact, the results show that both the numerical scheme of the inundation model and the gridding technique can contribute to deviations in simulated inundation extent as we control for model forcing and boundary conditions. This study shows

  12. The strategic decisions and success factors of the global integration-local responsiveness of Japanese MNCs in China

    MAO Yunshi; WANG Jiancheng

    2007-01-01

    This article applies Foreign Direct Investment (FDI) theories to the strategic management analysis of the global integration-local responsiveness of multinational corporations (MNCs) in China, from the perspective of company characteristics (ownership advantages and internalization advantages) and environmental dynamics (locational factors) in order to analyze the success factors influencing the sales activities of Japanese MNCs in China. Based on the analysis of a survey conducted on 230 Japanese parent companies with investments in China, the empirical research findings include: Japanese MNCs in China favor global integration strategies; the more significant the ownership advantages and internalization advantages are, the greater the global integration is; the success factors of their operations in China due to global integration are present in manufacturing know-how, procurement of parts and supplies, financial power, previous investment experience in China as well as sales networks and technologies; locational advantages mainly lie in labor cost among other things; internalization factors do not have any significant correlation with the success and performance of the subsidiary company.

  13. 76 FR 19174 - In the Matter of Circuit Systems, Inc., Global Energy Group, Inc., Integrated Medical Resources...

    2011-04-06

    ... SECURITIES AND EXCHANGE COMMISSION File No. 500-1 In the Matter of Circuit Systems, Inc., Global Energy Group, Inc., Integrated Medical Resources, Inc., iNTELEFILM Corp., and Lot$off Corp.; Order of... lack of current and accurate information concerning the securities of Circuit Systems, Inc. because it...

  14. Paved with good intentions: global financial integration, the eurozone, and the hellish road to the fabled gold standard

    Underhill, G.R.D.; Claes, D.H.; Knutsen, C.H.

    2011-01-01

    Regional systems of governance may resolve some of the dilemmas of global financial integration, and the eurozone is among the most advanced examples of attempts to do so. This paper argues that the recent Euroland sovereign debt crisis is a test of this proposition, and the outcome leaves the EU

  15. Paved with good intentions: global financial integration, the eurozone, and the imaginary road to the fabled gold standard

    Underhill, G.R.D.

    2010-01-01

    Regional systems of governance may resolve some of the dilemmas of global financial integration, and the eurozone is among the most advanced examples of attempts to do so. This paper argues that the recent Euroland sovereign debt crisis is a test of this proposition, and the outcome leaves the EU

  16. Global Economic Integration and Local Community Resilience: Road Paving and Rural Demographic Change in the Southwestern Amazon

    Perz, Stephen G.; Cabrera, Liliana; Carvalho, Lucas Araujo; Castillo, Jorge; Barnes, Grenville

    2010-01-01

    Recent years have witnessed an expansion in international investment in large-scale infrastructure projects with the goal of achieving global economic integration. We focus on one such project, the Inter-Oceanic Highway in the "MAP" region, a trinational frontier where Bolivia, Brazil, and Peru meet in the southwestern Amazon. We adopt a…

  17. Developing a common strategy for integrative global change research and outreach: the Earth System Science Partnership (ESSP)

    Leemans, R.; Asrar, G.; Canadell, J.G.; Ingram, J.; Larigauderie, A.; Mooney, H.; Nobre, C.; Patwardhan, A.; Rice, M.; Schmidt, F.; Seitzinger, S.; Virji, H.; Vörösmarthy, C.; Yuoung, O.

    2009-01-01

    The Earth System Science Partnership (ESSP) was established in 2001 by four global environmental change (GEC) research programmes: DIVERSITAS, IGBP, IHDP and WCRP. ESSP facilitates the study of the Earth's environment as an integrated system in order to understand how and why it is changing, and to

  18. Towards an integrative post-2015 sustainable development goal framework: Focusing on global justice – peace, security and basic human rights

    George R. Lueddeke

    2015-12-01

    To strengthen the likelihood of realizing the post-2015 Sustainable Development Goals (SDGs, particularly with regard to “planet and population” health and well-being , UN and other decision-makers are urged to consider the adoption of an integrated SDG framework that is based on (i a vision of global justice - underpinned by peace, security and basic human rights; (ii the development of interdependent and interconnected strategies for each of the eleven thematic indicators identified in the UN document The World We Want; and (iii the application of guiding principles to measure the impact of SDG strategies in terms of holism, equity, sustainability, ownership, and global obligation. While current discussions on the SDGs are making progress in a number of areas, the need for integration of these around a common global vision and purpose seems especially crucial to avoid MDG shortcomings.

  19. Global Integration, Non-Oil Export and Economic Growth in Nigeria

    Ozoemena Stanley Nwodo

    2017-03-01

    Full Text Available This study focuses on global integration, non-oil export and economic growth in Nigeria. The direct and interaction effect of the both openness variables and non-oil export on economic growth in Nigeria is investigated using quarterly data from 1986-2014. For analysis, it uses one measures of financial openness: de facto (total capital flow variables following Aizenman and Noy (2009.and a measure of trade openness adopted by Okoh (2004. The study applies the Autoregressive Distributed Lag Model (ARDL. The results show positive impact of non-oil export on economic growth in Nigeria both in the short run and in the long run, negative effect of trade and financial openness on economic growth however, the result recorded a negative effect of the interaction of trade openness and non-oil export on economic growth and a positive effect of the interaction of financial openness and non-oil export on economic growth. Thus, the study recommends among others that government should get the fundamentals right in the economy first that will boost non-oil sector before opening the economy for trade.

  20. Management model of productive capacity: integrating theory of constraints and the global operational efficiency index (IROG

    Diego Augusto Pacheco

    2012-08-01

    Full Text Available This paper presents a model of management capacity in productive systems integrating the concepts of the Theory of Constraints and Total Productive Maintenance (TPM. The main objective of this study is to discuss and propose a model of management capacity, able to answer the following key questions: i capacity indicators which should be considered and how to measure them to measure the productive capacity of manufacturing systems? ii what is the real productive capacity of the system analyzed under a determined relationship between capacity and demand? The discussion of the proposed model is relevant because the definition of productive capacity system enables better management of resources and capabilities, improve production scheduling on the factory floor and meeting the demands imposed by the market. This paper presents the proposition of using the Operating Income Index Global (IROG with a different approach from traditional literature dealing with the theme, presented by Nakajima (1988. The results of this paper enable to develop a model to determine the capacity of the production system and the impact on the productive capacity of the entire system, not to consider the quality conformances that occur after the bottleneck resource of the production flow.

  1. Integrating women's human rights into global health research: an action framework.

    Baptiste, Donna; Kapungu, Chisina; Khare, Manorama H; Lewis, Yvonne; Barlow-Mosha, Linda

    2010-11-01

    This article uses Scale of Change theory as a framework to guide global health researchers to synergistically target women's health outcomes in the context of improving their right to freedom, equity, and equality of opportunities. We hypothesize that health researchers can do so through six action strategies. These strategies include (1) becoming fully informed of women's human rights directives to integrate them into research, (2) mainstreaming gender in the research, (3) using the expertise of grass roots women's organizations in the setting, (4) showcasing women's equity and equality in the organizational infrastructure, (5) disseminating research findings to policymakers in the study locale to influence health priorities, and (6) publicizing the social conditions that are linked to women's diseases. We explore conceptual and logistical dilemmas in transforming a study using these principles and also provide a case study of obstetric fistula reduction in Nigeria to illustrate how these strategies can be operationalized. Our intent is to offer a feasible approach to health researchers who, conceptually, may link women's health to social and cultural conditions but are looking for practical implementation strategies to examine a women's health issue through the lens of their human rights.

  2. Integrative medical therapy: examination of meditation's therapeutic and global medicinal outcomes via nitric oxide (review).

    Stefano, George B; Esch, Tobias

    2005-10-01

    Relaxation techniques are part of the integrative medicine movement that is of growing importance for mainstream medicine. Complementary medical therapies have the potential to affect many physiological systems. Repeatedly studies show the benefits of the placebo response and relaxation techniques in the treatment of hypertension, cardiac arrhythmias, chronic pain, insomnia, anxiety and mild and moderate depression, premenstrual syndrome, and infertility. In itself, relaxation is characterized by a decreased metabolism, heart rate, blood pressure, and rate of breathing as well as an increase in skin temperature. Relaxation approaches, such as progressive muscle relaxation, autogenic training, meditation and biofeedback, are effective in lowering systolic and diastolic blood pressure in hypertensive patients by a significant margin. Given this association with changes in vascular tone, we have hypothesized that nitric oxide, a demonstrated vasodilator substance, contribute to physiological activity of relaxation approaches. We examined the scientific literature concerning the disorders noted earlier for their nitric oxide involvement in an attempt to provide a molecular rationale for the positive effects of relaxation approaches, which are physiological and cognitive process. We conclude that constitutive nitric oxide may crucially contribute to potentially beneficial outcomes and effects in diverse pathologies, exerting a global healing effect.

  3. Microseismic event location using global optimization algorithms: An integrated and automated workflow

    Lagos, Soledad R.; Velis, Danilo R.

    2018-02-01

    We perform the location of microseismic events generated in hydraulic fracturing monitoring scenarios using two global optimization techniques: Very Fast Simulated Annealing (VFSA) and Particle Swarm Optimization (PSO), and compare them against the classical grid search (GS). To this end, we present an integrated and optimized workflow that concatenates into an automated bash script the different steps that lead to the microseismic events location from raw 3C data. First, we carry out the automatic detection, denoising and identification of the P- and S-waves. Secondly, we estimate their corresponding backazimuths using polarization information, and propose a simple energy-based criterion to automatically decide which is the most reliable estimate. Finally, after taking proper care of the size of the search space using the backazimuth information, we perform the location using the aforementioned algorithms for 2D and 3D usual scenarios of hydraulic fracturing processes. We assess the impact of restricting the search space and show the advantages of using either VFSA or PSO over GS to attain significant speed-ups.

  4. A simple integrated assessment approach to global change simulation and evaluation

    Ogutu, Keroboto; D'Andrea, Fabio; Ghil, Michael

    2016-04-01

    We formulate and study the Coupled Climate-Economy-Biosphere (CoCEB) model, which constitutes the basis of our idealized integrated assessment approach to simulating and evaluating global change. CoCEB is composed of a physical climate module, based on Earth's energy balance, and an economy module that uses endogenous economic growth with physical and human capital accumulation. A biosphere model is likewise under study and will be coupled to the existing two modules. We concentrate on the interactions between the two subsystems: the effect of climate on the economy, via damage functions, and the effect of the economy on climate, via a control of the greenhouse gas emissions. Simple functional forms of the relation between the two subsystems permit simple interpretations of the coupled effects. The CoCEB model is used to make hypotheses on the long-term effect of investment in emission abatement, and on the comparative efficacy of different approaches to abatement, in particular by investing in low carbon technology, in deforestation reduction or in carbon capture and storage (CCS). The CoCEB model is very flexible and transparent, and it allows one to easily formulate and compare different functional representations of climate change mitigation policies. Using different mitigation measures and their cost estimates, as found in the literature, one is able to compare these measures in a coherent way.

  5. Technologies for water resources management: an integrated approach to manage global and regional water resources

    Tao, W. C., LLNL

    1998-03-23

    regional water resources; As an evaluation tool for selecting appropriate remediation technologies for reclaiming water; and As an assessment tool for determining the effectiveness of implementing the remediation technologies. We have included a discussion on the appropriate strategy for LLNL to integrate its technical tools into the global business, geopolitical, and academic communities, whereby LLNL can form partnerships with technology proponents in the commercial, industrial, and public sectors.

  6. A System of Systems Approach to Integrating Global Sea Level Change Application Programs

    Bambachus, M. J.; Foster, R. S.; Powell, C.; Cole, M.

    2005-12-01

    The global sea level change application community has numerous disparate models used to make predications over various regional and temporal scales. These models have typically been focused on limited sets of data and optimized for specific areas or questions of interest. Increasingly, decision makers at the national, international, and local/regional levels require access to these application data models and want to be able to integrate large disparate data sets, with new ubiquitous sensor data, and use these data across models from multiple sources. These requirements will force the Global Sea Level Change application community to take a new system-of-systems approach to their programs. We present a new technical architecture approach to the global sea level change program that provides external access to the vast stores of global sea level change data, provides a collaboration forum for the discussion and visualization of data, and provides a simulation environment to evaluate decisions. This architectural approach will provide the tools to support multi-disciplinary decision making. A conceptual system of systems approach is needed to address questions around the multiple approaches to tracking and predicting Sea Level Change. A systems of systems approach would include (1) a forum of data providers, modelers, and users, (2) a service oriented architecture including interoperable web services with a backbone of Grid computing capability, and (3) discovery and access functionality to the information developed through this structure. Each of these three areas would be clearly designed to maximize communication, data use for decision making and flexibility and extensibility for evolution of technology and requirements. In contemplating a system-of-systems approach, it is important to highlight common understanding and coordination as foundational to success across the multiple systems. The workflow of science in different applications is often conceptually similar

  7. Managing two cultural identities: the malleability of bicultural identity integration as a function of induced global or local processing.

    Mok, Aurelia; Morris, Michael W

    2012-02-01

    Increasingly, individuals identify with two or more cultures. Prior research has found the degree to which individuals chronically integrate these identities (bicultural identity integration; BII) moderates responses to cultural cues: High BII individuals assimilate (adopting biases that are congruent with norms of the cued culture), whereas low BII individuals contrast (adopting biases that are incongruent with these norms). The authors propose BII can also be a psychological state and modulated by shifts in processing styles. In four experiments, the authors induced a global or local processing style using physical posture (Experiment 1) and cognitive manipulations (Experiments 2-4) and found that BII is enhanced in contexts facilitating a more global processing style (i.e., smiling, high-level construal, and similarity focus). The authors also found that contrastive responses to cultural cues are diminished when BII is situationally enhanced. Implications for research on processing style, identity integration, and performance in culture-based situations are discussed.

  8. First detection of global dawn-dusk ionospheric current intensities using Ampere's integral law on Orsted orbits

    Stauning, P.; Primdahl, Fritz

    2000-01-01

    -to-dusk ionospheric current is found to be proportional to the gee-effective solar wind electric field and is around 1 million ampere for a typical solar wind electric field of 2 mV/m. Dividing the Ampere integral into semi-orbit parts has enabled us to show that the hemispherical total current intensities depend......The magnetic measurements by the Orsted satellite in noon-midnight orbits have enabled the derivation of the global dawn-dusk oriented ionospheric currents from an Ampere's law closed loop line integral of the geomagnetic vector field along the satellite track. The globally integrated dawn...... on the respective polar cap conductivities, which relate to the daily and seasonally varying solar illumination. The more illuminated hemisphere conveys up to three times more current from dawn to dusk than does the less illuminated....

  9. The Impact of Globalization on a Country's Quality of Life: Toward an Integrated Model

    Sirgy, M. Joseph; Lee, Dong-Jin; Miller, Chad; Littlefield, James E.

    2004-01-01

    The purpose of the paper is to develop a set of theoretical propositions to explain the impact of globalization on a country's quality of life (QOL). In this paper, we describe how globalization impacts the quality of life of residents of a country by first articulating the globalization construct (in terms of inflows and outflows of goods,…

  10. The MIT Integrated Global System Model: A facility for Assessing and Communicating Climate Change Uncertainty (Invited)

    Prinn, R. G.

    2013-12-01

    The world is facing major challenges that create tensions between human development and environmental sustenance. In facing these challenges, computer models are invaluable tools for addressing the need for probabilistic approaches to forecasting. To illustrate this, I use the MIT Integrated Global System Model framework (IGSM; http://globalchange.mit.edu ). The IGSM consists of a set of coupled sub-models of global economic and technological development and resultant emissions, and physical, dynamical and chemical processes in the atmosphere, land, ocean and ecosystems (natural and managed). Some of the sub-models have both complex and simplified versions available, with the choice of which version to use being guided by the questions being addressed. Some sub-models (e.g.urban air pollution) are reduced forms of complex ones created by probabilistic collocation with polynomial chaos bases. Given the significant uncertainties in the model components, it is highly desirable that forecasts be probabilistic. We achieve this by running 400-member ensembles (Latin hypercube sampling) with different choices for key uncertain variables and processes within the human and natural system model components (pdfs of inputs estimated by model-observation comparisons, literature surveys, or expert elicitation). The IGSM has recently been used for probabilistic forecasts of climate, each using 400-member ensembles: one ensemble assumes no explicit climate mitigation policy and others assume increasingly stringent policies involving stabilization of greenhouse gases at various levels. These forecasts indicate clearly that the greatest effect of these policies is to lower the probability of extreme changes. The value of such probability analyses for policy decision-making lies in their ability to compare relative (not just absolute) risks of various policies, which are less affected by the earth system model uncertainties. Given the uncertainties in forecasts, it is also clear that

  11. An integrated framework to address climate change (ESCAPE) and further developments of the global and regional climate modules (MAGICC)

    Hulme, M.; Raper, S.C.B.

    1995-01-01

    ESCAPE (the Evaluation of Strategies to address Climate change by Adapting to and Preventing Emissions) is an integrated climate change assessment model constructed between 1990 and 1992 for DG XI of the Commission of the European Community by a consortium of research institutes headed by the Climatic Research Unit (CRU). It has been designed to enable the user to generate future scenarios of greenhouse gas emissions (through an energy-economic model), examine their impact on global climate and sea level (through two independent global climate models), and illustrate some of the consequences of this global climate change at a regional scale for the European Community (through a regional climate scenario generator and impact models). We provide a very brief overview of the ESCAPE model which, although innovative, suffers from a number of major limitations. Subsequent work in the CRU has concentrated on improvements to the global climate module and work has also commenced on an improved regional climate scenario generating module. These improvements will lead to a new integrated climate change assessment model, MAGICC (Model for the Assessment of Greenhouse gas Induced Climate Change) which can easily be incorporated into new larger integrated frameworks developed by other institutes. (Author)

  12. Integrating scientific argumentation to improve undergraduate writing and learning in a global environmental change course

    Kreutz, K. J.; Koffman, B. G.; Trenbath, K. L.

    2013-12-01

    What makes a good scientific argument? We began ERS201: Global Environmental Change by asking students to reflect on the mechanics of a strong scientific argument. At the same time, we asked them to evaluate global CO2 and sea level data from different time periods in Earth's history to answer the question, 'Is there a relationship between atmospheric CO2 and sea level, and if so, why?' This question formed the theme for the course, a mid-level, inquiry-based class of about 20 students. Each week, students target specific aspects of the climate system through problem sets, which include experimental and laboratory work, basic statistical analyses of paleoclimate datasets, and the development of simple systems models using STELLA software. Every 2-4 weeks, we challenge students to write short (1500 word) data-driven scientific arguments, which require a synthesis of information from their problem sets and from the scientific literature. Students have to develop a clear, testable hypothesis related to each writing prompt, and then make their case using figures they have generated during the weekly problem sets. We evaluate student writing using a rubric that focuses on the structure and clarity of the argument, relevance of the data included, and integration and quality of the graphics, with a lesser emphasis placed on voice and style. In 2013, student scores improved from a median value of 86 × 9% to 94 × 8% over the course of the semester. More importantly, we found that incorporation of scientific argumentation served to increase student understanding of important and sometimes abstract scientific concepts. For example, on pre- and post-course assessments we asked the question, 'What would happen if a significant portion of the sea ice floating in the Arctic Ocean were to melt?' On the pre-assessment, 80% of students said that it would lead to more coastal flooding, while only 20% correctly stated that a decrease in the reflection of solar energy would lead to

  13. Integrated rice-duck farming mitigates the global warming potential in rice season.

    Xu, Guochun; Liu, Xin; Wang, Qiangsheng; Yu, Xichen; Hang, Yuhao

    2017-01-01

    Integrated rice-duck farming (IRDF), as a mode of ecological agriculture, is an important way to realize sustainable development of agriculture. A 2-year split-plot field experiment was performed to evaluate the effects of IRDF on methane (CH 4 ) and nitrous oxide (N 2 O) emissions and its ecological mechanism in rice season. This experiment was conducted with two rice farming systems (FS) of IRDF and conventional farming (CF) under four paddy-upland rotation systems (PUR): rice-fallow (RF), annual straw incorporating in rice-wheat rotation system (RWS), annual straw-based biogas residues incorporating in rice-wheat rotation system (RWB), and rice-green manure (RGM). During the rice growing seasons, IRDF decreased the CH 4 emission by 8.80-16.68%, while increased the N 2 O emission by 4.23-15.20%, when compared to CF. Given that CH 4 emission contributed to 85.83-96.22% of global warming potential (GWP), the strong reduction in CH 4 emission led to a significantly lower GWP of IRDF as compared to CF. The reason for this trend was because IRDF has significant effect on dissolved oxygen (DO) and soil redox potential (Eh), which were two pivotal factors for CH 4 and N 2 O emissions in this study. The IRDF not only mitigates the GWP, but also increases the rice yield by 0.76-2.43% compared to CF. Moreover, compared to RWS system, RF, RWB and RGM systems significantly reduced CH 4 emission by 50.17%, 44.89% and 39.51%, respectively, while increased N 2 O emission by 10.58%, 14.60% and 23.90%, respectively. And RWS system had the highest GWP. These findings suggest that mitigating GWP and improving rice yield could be simultaneously achieved by the IRDF, and employing suitable PUR would benefit for relieving greenhouse effect. Copyright © 2016 Elsevier B.V. All rights reserved.

  14. Canada and the North American Free Trade Agreement: Between globalization and regional integration

    Caterina García Segura

    1995-07-01

    Full Text Available The aim of the present article is to analize, from Canada’s perspective, the choice regarding the model of state as well as of economic and commercial policy which the decision to participate in the North American Free Trade Agreement (NAFTA implies. The debatewhich NAFTA provoked in Canada expresses in concrete terms that debate which, in much larger terms, takes place at the international level regarding the multilateralization and/or the regionalization of commercial exchanges. It is a reflection of the tension between theintegrating forces (process of globalization and the fragmenting ones (processes of regionalization which characterize the dynamics of the contemporary international system. The hypothesis of this work is that in spite of being a commercial agreement, the Canadian government’s decision to participate in NAFTA was a decision of a political nature which was not determined exclusively by the reality of the existing commercial exchanges between Canada and Mexico or by the perspectives of improving them inthe short term. The immediate objective of Canada was to avoid that a possible bilateral agreement between its prinicipal economic member, the United States, and Mexico would empty out the contents of the existing Free Trade Agreement (FTA between Canada and the United States. In this sense, NAFTA was the possible remedy to an unwanted situation (the negotiation of a US-Mexico bilateral agreement. The objective in the medium and long term is use the platform of regional integration as a trampoline from where the Canadian economy can be reorientated and driven in order to attain international competitiveness. In this sense, Canada’s true option had already beenrealised with the FTA.

  15. Formalizing knowledge on international environmental regimes: A first step towards integrating political science in integrated assessments of global environmental change

    de Vos, M.G.; Janssen, P.H.M.; Kok, M.T.J.; Frantzi, S.; Dellas, E.D.; Pattberg, P.H.; Petersen, A.C.; Biermann, F.

    2013-01-01

    International environmental regimes are considered key factors in dealing with global environmental change problems. It is important to understand if and how regimes are effective in tackling these problems, which requires knowledge on their potential impact on these problems as well as on their

  16. Issues Related to University Education in Ukraine in the Context of Globalization, European Integration and Bologna Process

    Maryna V. Bosenko

    2014-03-01

    Full Text Available The article deals with the analysis of issued linked to the development of Ukrainian education in the contexts of globalization, European integration and Bologna Process. The needs for reforms related to the university education in Ukraine is linked with job market and social services, including educational services, globalization of economics and IT technologies: enhancing of socio-economical and pedagogical processes, informatization in society, transition to ‘knowledge societies’, changing the system f values, expanding the core of university education, emergence and distribution of innovative technologies, freedom of choice in electing the university curriculum, fundamentalization and humanization of education etc.

  17. Energy principle with global invariants

    Bhattacharjee, A.; Dewar, R.L.

    1981-04-01

    A variational principle is proposed for constructing equilibria with minimum energy in a toroidal plasma. The total energy is minimized subject to global invariants which act as constraints during relaxation of the plasma. These global integrals of motion are preserved exactly for all idea motions and approximately for a wide class of resistive motions. We assume, specifically, that relaxation of the plasma is dominated by a tearing mode of single helicity. Equilibria with realistic current density and pressure profiles may be constructed in this theory, which is also used here to study current penetration in tokamaks. The second variation of the free energy functional is computed. It is shown that if the second variation of any equilibrium constructed in this theory is positive, the equilibrium satisfies the necessary and sufficient conditions for ideal stability

  18. Improvements in Quantifying Bank Erosion for Sediment Budgets within the Chesapeake Bay Watershed by Integrating Structure-From-Motion Photogrammetry

    Bell, J. M.; Cashman, M. J.; Nibert, L.; Jackson, S.

    2017-12-01

    Fine sediment is a major source of pollution due to its ability to attenuate light, smother habitat, and sorb and transport nutrients, such as phosphorus and nitrogen. Piedmont streams in the Mid-Atlantic region of the United States are frequently characterized as incised with steep, highly erodible banks of legacy sediment that can contribute to high sediment loads. Multiple sediment fingerprinting studies in this region have demonstrated that stream banks can contribute a large proportion of the total sediment load, but stream banks are frequently overlooked in sediment delivery models and Total Maximum Daily Load allocations. The direct quantification of bank erosion is therefore essential to producing accurate sediment budgets, which are needed to inform the targeted mitigation and remediation of degraded fluvial systems. This study contrasts the use of traditional bank pin measurements, structure-from-motion photogrammetric techniques, and aerial LIDAR at sites within Maryland, USA. Bank pin measurements, representing only single points in space, were found to be highly variable with subjective initial placement often missing nearby, large-scale bank failures. In contrast, photogrammetric techniques, using structure-from-motion, were able to capture a more spatially-complete streambank profile. Using a Nikon D810 camera, bank scans were able to reconstruct banks with a RMSE as low as 0.1mm and repeat scan alignment resolution of bank-erosion over multi-year timescales. Future work will include difference mapping channel features at watershed scales. This photogrammetric approach of quantifying geomorphic change, when coupled with bank-sediment bulk density, has promise to accurately quantify volumetric change as well as sediment loads originating from bank erosion, and may provide valuable data of the quantification of bank erosion for incorporation into regional sediment models.

  19. Processes Adopted to Integrate Intangible Resources in Global Acquisitions among Container Lines: Perceptions of Acquirer and Acquired

    Indika Sigera

    2018-03-01

    Full Text Available The spectrum of strategic co-operations among container lines varies from loose-knitted slot charters, liner conferences, shipping alliances, joint services and consortia, through to mergers and acquisitions (M&As. However, these forms of strategic co-operations have not always been able to achieve the intended synergetic growth resulting from the integration of resources. The Resource Based View (RBV suggests that integrating intangible resources, which are valuable, rare, inimitable and non-substitutable (VRIN, can make a significant contribution to the performance of post strategic co-operations. This research paper investigates the contribution of intangible resources to the post acquisition success six global acquisitions among container lines. The nine senior managers attached to global container lines were the main participants of this study. Five of them represented acquired container lines, four represented acquirer container lines. The paper explains their personnel experience on the processes adopts to integrate intangible resources in acquisitions. Keywords: Merger and Acquisitions, Intangible Resources, Container Lines, Task Integration, Human Integration

  20. Results on an integral inequality of the opial- type | Rauf | Global ...

    Abstract. We obtain integral inequalities which are Opial-type inequalities, mainly by using Jensen's inequality for the case of convex function. Keywords: Integral inequalities, Opial's inequality, Jensen's inequality and convex functions ...

  1. Comparison of dosimetry distribution between three-dimension conformal and intensity modulated plan integrated with breath motion in postoperative radiation of gastric cancer

    Sun Wenjie; Zhang Zhen; Hu Weigang; Gu Weilie; Zhu Ji; Li Guichao; Cai Gang; Ma Xuejun

    2010-01-01

    Objective: To compare the dose distribution of the target and normal tissues in gastric cancers between three-dimension conformal radiation therapy (3DCRT) and intensity modulated radiation therapy (IMRT) plan when respiratory motion factors integrated in the plan. Methods: From January 2005 to November 2006, 10 patients with post-operatively radiation of gastric cancer were enrolled in this study. Planning CT were acquired conventionally with free-breath mode and the static treatment plans of the 3DCRT and IMRT were designed respectively. Probability distribution functions (PDF) were generated and convoluted with the static dose distributions from 3DCRT and IMRT plans to obtain the integrated plans. The dose distributions of the target and normal tissues were compared between 3DCRT and IMRT integration treatment plans, such as V 45 of clinical target volume, V 40 of liver and V 15 , V 18 of left and right kidney. Results: In the respiratory integrated treatment planning, the target volume coverage and homogeneity with IMRT are superior to those with 3DCRT ((V 45 98% : 87% (t = -3.35, P =0.010), mean dose 46.81 Gy ±0.75 Gy : 45.99 Gy ± 1.12 Gy (t = -0.31, P=0.020)). The V 40 of the liver in IMRT are smaller than those in 3DCRT ( 12% : 16%; t=3.75, P=0.010). For the left kidney, the V 15 and V 18 in IMRT are smaller than those in 3DCRT ((34% : 50% (t = 2.17, P = 0.050) and 27% : 46% (t = 3.11, P = 0.020) ),but for the right kidney, V 15 and V 18 in 3DCRT are smaller than those in IMRT ((15% : 21% (t = - 2.42, P=0.040) and 11% : 15% (t= -2.71, P=0.030)). Conclusions: When respiratory motion factor integrated in the treatment plan, IMRT showed advantage both in target coverage and normal tissue sparing in the high dose region of liver and left kidney. (authors)

  2. Teaching Children about the Global Economy: Integrating Inquiry with Human Rights

    McCall, Ava L.

    2017-01-01

    Although children are already part of the global economy, they often have little understanding of its influence without explicit instruction. The article focuses on recommendations for teaching elementary students in grades three through five about the global economy utilizing the pedagogical recommendations from the National Council for the…

  3. Measurements of integrated direct, diffuse and global ultraviolet-B radiation

    Utrillas, M.P.; Pedrós, R.; Gandía, S.; Gómez-Amo, J.L.; Estellés, V.; Martínez-Lozano, J.A.

    2015-01-01

    We present the first multiyear set of simultaneous measurements of the global ultraviolet-B radiation and its two components: direct and diffuse. The measurements have been taken with four YES-UVB-1 radiometers: two radiometers to measure the diffuse radiation, one provided with a shadow band and the other with a shadow disk on a Sun tracker; a radiometer to measure the global horizontal radiation; and a Sun-tracking radiometer to measure the direct radiation with an especially designed radiance collimator. The diffuse minute-values measured with both instruments agree within a coefficient correlation of 1.00. The diffuse component represents at least 50% of the global UVB (ultraviolet-B) radiation. The minute values of global UVB irradiance obtained by adding the direct and diffuse components concur with the measured global irradiance. Therefore, the measurement of the direct irradiance enables the estimation of the diffuse component, and gives an insight into the factors that affect its value, especially aerosols. - Highlights: • Simultaneous measurements of global, direct and diffuse UVB (ultraviolet-B) radiation. • The diffuse minute-values are at least 50% of the global ones. • The diffuse measurements are highly correlated to the aerosol load. • The sum of direct + diffuse radiation concur with the measured global.

  4. Communication Policies Reflection on Globalization Process and the Role of Advertisement in Integrated Communication Environment

    ÖZKAN, Abdullah

    2012-01-01

    Globalization process has created important changes and transformations across the world. These political, social, economic and cultural changes have considerably affected communication. The number of mass media instruments have increased, informatics has improved and also reaching information has become easier after the globalization of communication. New communication instruments and environments have been created. Globalised communication has also affected people, reaching the information ...

  5. To assess and control global change in agriculture through ecosystem models integrated into geographic information systems

    Ponti, L.; Iannetta, M.; Gutierrez, A.P.

    2015-01-01

    The transfer of ENEA PBDM (physiologically based demographic models) GIS technology, represents an opportunity to address global change in agriculture on an ecological basis in a local context, be able to provide European governmental agencies the necessary scientific basis for developing effective policies for adaptation to global change, including climate change [it

  6. Integrated assessment of global climate change with learning-by-doing and energy-related research and development

    Mueller-Fuerstenberger, Georg; Stephan, Gunter

    2007-01-01

    This paper presents a small-scale version of an Integrated Assessment Model (IAM) of global climate change, which is based on a global, regionally differentiated computable general equilibrium (CGE) model with endogenous technological change. This model can be viewed as a basic framework for analyzing a broad range of economic issues related to climate change, in particular since technological change is represented in two ways: on the one hand, there is learning-by-doing (LbD) in non-fossil energy supply technologies, and on the other hand there is research and development (R and D)-driven energy-saving technical progress in production. Computational experiments are added for illustrating the role of technological innovation in a world both with and without cooperation in the solution of the global climate problem

  7. Feasibility of integrating other federal information systems into the Global Network of Environment and Technology, GNET{reg_sign}

    NONE

    1998-05-01

    The Global Environment and Technology Enterprise (GETE) of the Global Environment and Technology Foundation (GETF) has been tasked by the US Department of Energy`s (DOE), Federal Energy Technology Center (FETC) to assist in reducing DOE`s cost for the Global Network of Environment and Technology (GNET{reg_sign}). As part of this task, GETE is seeking federal partners to invest in GNET{reg_sign}. The authors are also seeking FETC`s commitment to serve as GNET`s federal agency champion promoting the system to potential agency partners. This report assesses the benefits of partnering with GNET{reg_sign} and provides recommendations for identifying and integrating other federally funded (non-DOE) environmental information management systems into GNET{reg_sign}.

  8. New methods for the numerical integration of ordinary differential equations and their application to the equations of motion of spacecraft

    Banyukevich, A.; Ziolkovski, K.

    1975-01-01

    A number of hybrid methods for solving Cauchy problems are described on the basis of an evaluation of advantages of single and multiple-point numerical integration methods. The selection criterion is the principle of minimizing computer time. The methods discussed include the Nordsieck method, the Bulirsch-Stoer extrapolation method, and the method of recursive Taylor-Steffensen power series.

  9. Integrating Global Open Geo-Information for Major Disaster Assessment: A Case Study of the Myanmar Flood

    Suju Li

    2017-07-01

    Full Text Available Major disasters typically impact large areas, cause considerable damages, and result in significant human and economic losses. The timely and accurate estimation of impacts and damages is essential to better understand disaster conditions and to support emergency response operations. Geo-information drawn from various sources at multi spatial-temporal scales can be used for disaster assessments through a synthesis of hazard, exposure, and post disaster information based on pertinent approaches. Along with the increased availability of open sourced data and cooperation initiatives, more global scale geo-information, including global land cover datasets, has been produced and can be integrated with other information for disaster dynamic damage assessment (e.g., impact estimation immediately after a disaster occurs, physical damage assessment during the emergency response stage, and comprehensive assessment following an emergency response. Residential areas and arable lands affected by the flood disaster occurring from July to August 2015 in Myanmar were assessed based on satellite images, GlobeLand30 data, and other global open sourced information as a study case. The results show that integrating global open geo-information could serve as a practical and efficient means of assessing damage resulting from major disasters worldwide, especially at the early emergency response stage.

  10. Integration of Financial Markets in Post Global Financial Crises and Implications for British Financial Sector: Analysis Based on A Panel VAR Model

    Nasir, M; Du, M

    2017-01-01

    This study analyses the dynamics of integration among global financial markets in the context of Global Financial Crisis (2008) by employing a Panel Vector Autoregressive (VAR) model on the monthly data of nine countries and three markets from Jan 2003 to Oct 2015. It was found that there has been a shift in the association among the global financial markets since Global Financial Crisis (GFC).Moreover, the British financial sectors in Post-GFC world clearly showed a change in the association...

  11. Assess and control global change in agriculture through ecosystem models integrated in geographic information systems

    Ponti, Luigi; Gutierrez, Andrew Paul; Iannetta, Massimo

    2015-01-01

    ENEA has created, in collaboration with the University of California at Berkeley, the Global Change Biology project that, for the first time, has made available in Europe a technology that can be It used to interpret and effectively manage change Global agriculture. The aim of the project was to provide tools to summarize, manage and analyze data Ecological on the effects of global change in agricultural systems, using traditional Mediterranean crops (Eg. Vineyards and olive) as model systems (http: // cordis.europa.eu/project/rcn/89728_en.html). [it

  12. An Enhanced Error Model for EKF-Based Tightly-Coupled Integration of GPS and Land Vehicle's Motion Sensors.

    Karamat, Tashfeen B; Atia, Mohamed M; Noureldin, Aboelmagd

    2015-09-22

    Reduced inertial sensor systems (RISS) have been introduced by many researchers as a low-cost, low-complexity sensor assembly that can be integrated with GPS to provide a robust integrated navigation system for land vehicles. In earlier works, the developed error models were simplified based on the assumption that the vehicle is mostly moving on a flat horizontal plane. Another limitation is the simplified estimation of the horizontal tilt angles, which is based on simple averaging of the accelerometers' measurements without modelling their errors or tilt angle errors. In this paper, a new error model is developed for RISS that accounts for the effect of tilt angle errors and the accelerometer's errors. Additionally, it also includes important terms in the system dynamic error model, which were ignored during the linearization process in earlier works. An augmented extended Kalman filter (EKF) is designed to incorporate tilt angle errors and transversal accelerometer errors. The new error model and the augmented EKF design are developed in a tightly-coupled RISS/GPS integrated navigation system. The proposed system was tested on real trajectories' data under degraded GPS environments, and the results were compared to earlier works on RISS/GPS systems. The findings demonstrated that the proposed enhanced system introduced significant improvements in navigational performance.

  13. GLOBALIZATION AND INTEGRATION INTO THE ECONOMIC AND MONETARY UNION-CHALLENGES FOR BANKS OPERATING IN ROMANIA

    CORALIA EMILIA POPA

    2012-01-01

    Full Text Available This paper aims to present recent evolution, but also the consequences of globalization of the banking sector, considering different approaches of this phenomenon. Over time, the banking field has undergone important changes in both the applicable law of this area, and through the technologies used in satisfying the customers’ needs. The development of international markets has led to new opportunities and challenges for banks that transformed the domestic financial market into an arena where only the best survive and grow. On these grounds and in strict relation to positive and negative effects of globalization, we can speak of a constant evolution of its most important subsystems - the financial subsystems of the global economy. In this paper special importance is given to the banking field, the article presenting arguments through which this complex phenomenon called globalization may have important consequences on financial supervision and regulation.

  14. Integrating sustainability in the core business : From global goals to local application

    Frid, Gustav

    2016-01-01

    In 2016, the work towards a more sustainable world increased momentum when the new 17 Sustainable Development Goals (SDG) came into force. Now the SDGs will serve as a global agreement in the work towards ending all forms of poverty, fight inequality and tackle climate change for the next fifteen years. By using standardized Environmental Management Systems (EMS) together with global goals, the author aims on finding ways in how consultancy companies can develop their environmental and sustai...

  15. OPPORTUNITIES AND OBSTACLES TO EUROPEAN INTEGRATION, DEPENDING ON THE FUTURE OF THE GLOBAL SYSTEM

    DUŢĂ ALEXANDRU

    2017-12-01

    Full Text Available The hypothesis of the paper is that the future of the European Union cannot be understood outside of the global context. Here are the main strategic options for the 21st century - Friedman, Attali, Fukuyama and Huntigton. Without denying any possible conflicts, a global war involving the nucleus of the great civilizations is highly unlikely. Our view is that the United States of Europe is a strategically achievable target, bringing some arguments in favor of the advanced hypothesis.

  16. Global Value Chain Integration and Productivity : Evidence from Enterprise Surveys in Namibia, South Africa, and Swaziland

    Winkler, Deborah; Farole, Thomas

    2015-01-01

    In order to adequately measure a firm’s participation in GVCs in this context, it is important to first identify the different forms through which GVC integration can affect domestic firms’ productivity. Integrating a country’s domestic suppliers into GVCs increases the possibility for productivity gains through exporting to a buyer abroad or supplying to a multinational in the country. Bu...

  17. Integrating information systems : linking global business goals to local database applications

    Dignum, F.P.M.; Houben, G.J.P.M.

    1999-01-01

    This paper describes a new approach to design modern information systems that offer an integrated access to the data and knowledge that is available in local applications. By integrating the local data management activities into one transparent information distribution process, modern organizations

  18. Harmonic motion imaging for focused ultrasound (HMIFU): a fully integrated technique for sonication and monitoring of thermal ablation in tissues

    Maleke, C; Konofagou, E E

    2008-01-01

    FUS (focused ultrasound), or HIFU (high-intensity-focused ultrasound) therapy, a minimally or non-invasive procedure that uses ultrasound to generate thermal necrosis, has been proven successful in several clinical applications. This paper discusses a method for monitoring thermal treatment at different sonication durations (10 s, 20 s and 30 s) using the amplitude-modulated (AM) harmonic motion imaging for focused ultrasound (HMIFU) technique in bovine liver samples in vitro. The feasibility of HMI for characterizing mechanical tissue properties has previously been demonstrated. Here, a confocal transducer, combining a 4.68 MHz therapy (FUS) and a 7.5 MHz diagnostic (pulse-echo) transducer, was used. The therapy transducer was driven by a low-frequency AM continuous signal at 25 Hz, producing a stable harmonic radiation force oscillating at the modulation frequency. A pulser/receiver was used to drive the pulse-echo transducer at a pulse repetition frequency (PRF) of 5.4 kHz. Radio-frequency (RF) signals were acquired using a standard pulse-echo technique. The temperature near the ablation region was simultaneously monitored. Both RF signals and temperature measurements were obtained before, during and after sonication. The resulting axial tissue displacement was estimated using one-dimensional cross correlation. When temperature at the focal zone was above 48 deg. C during heating, the coagulation necrosis occurred and tissue damage was irreversible. The HMI displacement profiles in relation to the temperature and sonication durations were analyzed. At the beginning of heating, the temperature at the focus increased sharply, while the tissue stiffness decreased resulting in higher HMI displacements. This was confirmed by an increase of 0.8 μm deg. C -1 (r = 0.93, p -1 , r = -0.92, p -1 , prior to and after lesion formation in seven bovine liver samples, respectively. This technique was thus capable of following the protein-denatured lesion formation based on the

  19. The contribution of biomass burning to global warming: An integrated assessment

    Lashof, D.A.

    1991-01-01

    An analysis of studies of emissions form biomass burning suggests that while biomass burning is less significant than fossil fuel combustion on global basis, it is a major contributor to the greenhouse gas buildup, responsible for perhaps 10% to 15% of the total forcing from current emissions. Uncertainties about emissions and the relative impact of different gases are large, yielding a range of 5% to 30%. Nonetheless, biomass burning is probably the dominant source of greenhouse gases in some regions. A comprehensive policy to limit global climate change must, therefore, address biomass burning

  20. The Integration Aspects of Activities of the Companies in the Oil and Gas Industry Sector in the Context of Globalization

    Panevnyk Tetiana M.

    2016-05-01

    Full Text Available The article considers both the dynamics and the structure of oil and gas production in Ukraine, situation of the oil and gas companies at the current stage of globalization of the world economy have been covered. The main problems impacting the functioning of the domestic industry sector have been identified, including the lack of effectiveness of the existing integration processes. The world trends and patterns of integration processes have been considered. It has been determined that the oil and gas industry sector leaders are the multinational companies that actively use integration in their practices. The current trends in creating integration linkages in different parts of the process chain in the oil and gas industry have been identified. Influence by large corporations of the innovative type on the creation of a favorable investment climate has been confirmed, as well as conducting their own policies of expansion in the overseas markets. On the basis of studying the foreign experience, expediency of development of the oil and gas sector enterprises by activating integration processes has been substantiated. Priorities and possibilities for further functioning of enterprises in the the oil and gas industry sector have been identified

  1. Averaging, not internal noise, limits the development of coherent motion processing

    Catherine Manning

    2014-10-01

    Full Text Available The development of motion processing is a critical part of visual development, allowing children to interact with moving objects and navigate within a dynamic environment. However, global motion processing, which requires pooling motion information across space, develops late, reaching adult-like levels only by mid-to-late childhood. The reasons underlying this protracted development are not yet fully understood. In this study, we sought to determine whether the development of motion coherence sensitivity is limited by internal noise (i.e., imprecision in estimating the directions of individual elements and/or global pooling across local estimates. To this end, we presented equivalent noise direction discrimination tasks and motion coherence tasks at both slow (1.5°/s and fast (6°/s speeds to children aged 5, 7, 9 and 11 years, and adults. We show that, as children get older, their levels of internal noise reduce, and they are able to average across more local motion estimates. Regression analyses indicated, however, that age-related improvements in coherent motion perception are driven solely by improvements in averaging and not by reductions in internal noise. Our results suggest that the development of coherent motion sensitivity is primarily limited by developmental changes within brain regions involved in integrating motion signals (e.g., MT/V5.

  2. Global model of the upper atmosphere with a variable step of integration in latitude

    Namgaladze, A.A.; Martynenko, O.V.; Namgaladze, A.N.

    1996-01-01

    New version of model for the Earth thermosphere, ionosphere and protonosphere with increased spatial distribution, realized at personal computer, is developed. Numerical solution algorithm for modeling equations solution, which makes it possible to apply variable (depending on latitude) integrating pitch by latitude and to increase hereby the model latitude resolutions in the latitude zones of interest. Comparison of the model calculational results of ionosphere and thermosphere parameters, accomplished with application of different integrating pitches by geomagnetic latitude, is conducted. 10 refs.; 3 figs

  3. Tracking Global Fund HIV/AIDS resources used for sexual and reproductive health service integration: case study from Ethiopia.

    Mookherji, Sangeeta; Ski, Samantha; Huntington, Dale

    2015-05-27

    The Global Fund to Fight AIDS, Tuberculosis & Malaria (GF) strives for high value for money, encouraging countries to integrate synergistic services and systems strengthening to maximize investments. The GF needs to show how, and how much, its grants support more than just HIV/AIDS, TB and malaria. Sexual and Reproductive Health (SRH) has been part of HIV/AIDS grants since 2007. Previous studies showed the GF PBF system does not allow resource tracking for SRH integration within HIV/AIDS grants. We present findings from a resource tracking case study using primary data collected at country level. Ethiopia was the study site. We reviewed data from four HIV/AIDS grants from January 2009-June 2011 and categorized SDAs and activities as directly, indirectly, or not related to SRH integration. Data included: GF PBF data; financial, performance, in-depth interview and facility observation data from Ethiopia. All HIV/AIDS grants in Ethiopia support SRH integration activities (12-100%). Using activities within SDAs, expenditures directly supporting SRH integration increased from 25% to 66% for the largest HIV/AIDS grant, and from 21% to 34% for the smaller PMTCT-focused grant. Using SDAs to categorize expenditures underestimated direct investments in SRH integration; activity-based categorization is more accurate. The important finding is that primary data collection could not resolve the limitations in using GF GPR data for resource tracking. The remedy is to require existing activity-based budgets and expenditure reports as part of PBF reporting requirements, and make them available in the grant portfolio database. The GF should do this quickly, as it is a serious shortfall in the GF guiding principle of transparency. Showing high value for money is important for maximizing impact and replenishments. The Global Fund should routinely track HIV/AIDs grant expenditures to disease control, service integration, and overall health systems strengthening. The current PBF system

  4. Integrity of Cerebellar Fastigial Nucleus Intrinsic Neurons Is Critical for the Global Ischemic Preconditioning

    Eugene V. Golanov

    2017-09-01

    Full Text Available Excitation of intrinsic neurons of cerebellar fastigial nucleus (FN renders brain tolerant to local and global ischemia. This effect reaches a maximum 72 h after the stimulation and lasts over 10 days. Comparable neuroprotection is observed following sublethal global brain ischemia, a phenomenon known as preconditioning. We hypothesized that FN may participate in the mechanisms of ischemic preconditioning as a part of the intrinsic neuroprotective mechanism. To explore potential significance of FN neurons in brain ischemic tolerance we lesioned intrinsic FN neurons with excitotoxin ibotenic acid five days before exposure to 20 min four-vessel occlusion (4-VO global ischemia while analyzing neuronal damage in Cornu Ammoni area 1 (CA1 hippocampal area one week later. In FN-lesioned animals, loss of CA1 cells was higher by 22% compared to control (phosphate buffered saline (PBS-injected animals. Moreover, lesion of FN neurons increased morbidity following global ischemia by 50%. Ablation of FN neurons also reversed salvaging effects of five-minute ischemic preconditioning on CA1 neurons and morbidity, while ablation of cerebellar dentate nucleus neurons did not change effect of ischemic preconditioning. We conclude that FN is an important part of intrinsic neuroprotective system, which participates in ischemic preconditioning and may participate in naturally occurring neuroprotection, such as “diving response”.

  5. Plumbing the global carbon cycle: Integrating inland waters into the terrestrial carbon budget

    Cole, J.; Prairie, Y.T.; Caraco, N.; McDowell, W.H.; Tranvil, L.; Striegl, R.G.; Duarte, C.M.; Kortelainen, P.; Downing, J.A.; Middelburg, J.J.; Melack, J.

    2007-01-01

    Because freshwater covers such a small fraction of the Earth’s surface area, inland freshwater ecosystems (particularly lakes, rivers, and reservoirs) have rarely been considered as potentially important quantitative components of the carbon cycle at either global or regional scales. By taking

  6. Knowledge that Counts in a Global Community: Exploring the Contribution of Integrated Curriculum

    Rennie, Leonie J.; Venville, Grady; Wallace, John

    2011-01-01

    As the third millennium progresses, we are faced with increasing pressures relating to climate change and the sustainability of life on Earth. Concerned citizens are realizing that the responsibility to respond is both local and global. There is an increasing sense of urgency about the need to reform the processes of schooling and curriculum to…

  7. THE IMPACT OF EUROPEAN INTEGRATION AND FINANCIAL GLOBALIZATION ON PRUDENTIAL SUPERVISION

    Filip Angela Maria

    2009-05-01

    Full Text Available As a result of the financial market globalization during the last two decades, the conventional barriers between financial activities have diminished. This led to the emergence of financial holdings that operate both in the banking sector and on the stock

  8. The Global Positioning System and Its Integration into College Geography Curricula.

    Wikle, Thomas A.; Lambert, Dean P.

    1996-01-01

    Introduces global positioning system (GPS) technology to nonspecialist geographers and recommends a framework for implementing GPS instructional modules in college geography courses. GPS was developed as a worldwide satellite-based system by the U.S. Department of Defense to simplify and improve military and civilian navigation and positioning.…

  9. Academic Integrity, Remix Culture, Globalization: A Canadian Case Study of Student and Faculty Perceptions of Plagiarism

    Evans-Tokaryk, Tyler

    2014-01-01

    This article presents the results of a case study at a Canadian university that used a combination of surveys and focus groups to explore faculty members' and students' perceptions of plagiarism. The research suggests that the globalization of education and remix culture have contributed to competing and contradictory understandings of plagiarism…

  10. A global energy network? The expansion and integration of non-triad national oil companies

    de Graaff, N.A.

    2011-01-01

    It is widely perceived that the rising influence of state-owned energy companies from outside the traditional triad (USA, EU, Japan) is transforming the structure of the global energy market and generating a new wave of resource-nationalism. There is, however, little empirical analysis of how this

  11. Integration in the Global South: What Role for IBSA Dialogue Forum?

    Mehmet ÖZKAN

    2011-01-01

    Full Text Available Recently we have seen that the middle-sized states are coming together inseveral forums. The WTO meetings and India-Brazil-South Africa (IBSA dialogueforum are among those to be cited. Such groupings are mainly economyorientedand whether they will have political output needs to be seen, however,in the future if globalization goes in a similar way as today, we might see moregroupings. Those groupings should be seen as reactions to unjust and exclusiveglobalization. The IBSA Dialogue Forum members have enhanced their relationseconomically by signing bilateral trade agreements and acting together oneconomic issues in global forums. If they can hold together, they are creating amarket more than ¼ of global population and, if successful, it has a chance tobe the engine of growth in the South. Moreover if they can create the biggestmarket in the South, they would also be influential in the being of the voiceof the South. In that sense, this paper addresses the possible ways to developrelations between the IBSA members and economic development in the South,furthermore, implication of the IBSA on global governance and developmentcan be as critical as its contribution to economic development, since the globalgoverning bodies have legitimacy crisis.

  12. Effective motion design applied to energy-efficient handling processes

    Brett, Tobias

    2013-10-01

    Industrial robots are available in a large variety of mechanical alternatives regarding size, motor power, link length ratio or payload. The four major types of serial kinematics dominating the market are complemented by various parallel kinematics for special purpose. In contrast, few other path planning alternatives are applied in industrial robotics which are based on similar analytic solution principles. The objective of this thesis is to develop a systematic design method for artifacts in motion, to integrate motion design and mechanical design to enable new processes for production. For each design, a theoretical benchmark is developed, which cannot be attained by conventional robots in principle. A key performance indicator enables to measure the degree of goal achievement towards the benchmark during all design phases. Motion behaviors are identified on a local level by dynamic systems modeling and are integrated into new global behavior featuring a new quality, suitable for exceeding the design benchmark in industrial processes. Two exemplary handling robot designs are presented. The first concept enables motion behavior to consume less electrical power than kinetic energy transferred to and from its payload during motion. The second concept enables motion with four degrees of freedom by single motor stimulation, reducing idle power consumption on factor 4 towards conventional robots.

  13. Book Review: Jandl, Thomas, Vietnam in the Global Economy – The Dy-namics of Integration, Decentralization and Contested Politics

    Adam Fforde

    2014-01-01

    Full Text Available Book Review of the Monograph: Thomas Jandl (2013, Vietnam in the Global Economy – The Dynamics of Integration, Decentralization and Contested Politics. Plymouth: Lexington Books, ISBN 978-0-7391-7786-0, 312 pages

  14. A new integrated and homogenized global monthly land surface air temperature dataset for the period since 1900

    Xu, Wenhui; Li, Qingxiang; Jones, Phil; Wang, Xiaolan L.; Trewin, Blair; Yang, Su; Zhu, Chen; Zhai, Panmao; Wang, Jinfeng; Vincent, Lucie; Dai, Aiguo; Gao, Yun; Ding, Yihui

    2018-04-01

    A new dataset of integrated and homogenized monthly surface air temperature over global land for the period since 1900 [China Meteorological Administration global Land Surface Air Temperature (CMA-LSAT)] is developed. In total, 14 sources have been collected and integrated into the newly developed dataset, including three global (CRUTEM4, GHCN, and BEST), three regional and eight national sources. Duplicate stations are identified, and those with the higher priority are chosen or spliced. Then, a consistency test and a climate outlier test are conducted to ensure that each station series is quality controlled. Next, two steps are adopted to assure the homogeneity of the station series: (1) homogenized station series in existing national datasets (by National Meteorological Services) are directly integrated into the dataset without any changes (50% of all stations), and (2) the inhomogeneities are detected and adjusted for in the remaining data series using a penalized maximal t test (50% of all stations). Based on the dataset, we re-assess the temperature changes in global and regional areas compared with GHCN-V3 and CRUTEM4, as well as the temperature changes during the three periods of 1900-2014, 1979-2014 and 1998-2014. The best estimates of warming trends and there 95% confidence ranges for 1900-2014 are approximately 0.102 ± 0.006 °C/decade for the whole year, and 0.104 ± 0.009, 0.112 ± 0.007, 0.090 ± 0.006, and 0.092 ± 0.007 °C/decade for the DJF (December, January, February), MAM, JJA, and SON seasons, respectively. MAM saw the most significant warming trend in both 1900-2014 and 1979-2014. For an even shorter and more recent period (1998-2014), MAM, JJA and SON show similar warming trends, while DJF shows opposite trends. The results show that the ability of CMA-LAST for describing the global temperature changes is similar with other existing products, while there are some differences when describing regional temperature changes.

  15. Development and validation of a new global well-being outcomes rating scale for integrative medicine research

    Bell Iris R

    2004-01-01

    Full Text Available Abstract Background Researchers are finding limitations of currently available disease-focused questionnaire tools for outcome studies in complementary and alternative medicine/integrative medicine (CAM/IM. Methods Three substudies investigated the new one-item visual analogue Arizona Integrative Outcomes Scale (AIOS, which assesses self-rated global sense of spiritual, social, mental, emotional, and physical well-being over the past 24 hours and the past month. The first study tested the scale's ability to discriminate unhealthy individuals (n = 50 from healthy individuals (n = 50 in a rehabilitation outpatient clinic sample. The second study examined the concurrent validity of the AIOS by comparing ratings of global well-being to degree of psychological distress as measured by the Brief Symptom Inventory (BSI in undergraduate college students (N = 458. The third study evaluated the relationships between the AIOS and positively- and negatively-valenced tools (Positive and Negative Affect Scale and the Positive States of Mind Scale in a different sample of undergraduate students (N = 62. Results Substudy (i Rehabilitation patients scored significantly lower than the healthy controls on both forms of the AIOS and a current global health rating. The AIOS 24-hours correlated moderately and significantly with global health (patients r = 0.50; controls r = 0.45. AIOS 1-month correlations with global health were stronger within the controls (patients r = 0.36; controls r = 0.50. Controls (r = 0.64 had a higher correlation between the AIOS 24-hour and 1-month forms than did the patients (r = 0.33, which is consistent with the presumptive improvement in the patients' condition over the previous 30 days in rehabilitation. Substudy (ii In undergraduate students, AIOS scores were inversely related to distress ratings, as measured by the global severity index on the BSI (rAIOS24h = -0.42, rAIOS1month = -0.40. Substudy (iii AIOS scores were significantly

  16. The Global Network of Isotopes in Rivers (GNIR): Integration of Stable Water Isotopes in Riverine Research and Management

    Halder, J.; Terzer, S.; Wassenaar, L.; Araguas, L.; Aggarwal, P.

    2015-01-01

    Rivers play a crucial role in the global water cycle as watershed-integrating hydrological conduits for returning terrestrial precipitation, runoff, surface and groundwater, as well as melting snow and ice back to the world’s oceans. The IAEA Global Network of Isotopes in Rivers (GNIR) is the coherent extension of the IAEA Global Network for Isotopes in Precipitation (GNIP) and aims to fill the informational data gaps between rainfall and river discharge. Whereas the GNIP has been surveying the stable hydrogen and oxygen isotopes, and tritium composition in precipitation, the objective of GNIR is to accumulate and disseminate riverine isotope data. We introduce the new global database of riverine water isotopes and evaluate its current long-term data holdings with the objective to improve the application of water isotopes and to inform water managers and researchers. An evaluation of current GNIR database holdings confirmed that seasonal variations of the stable water isotope composition in rivers are closely coupled to precipitation and snow-melt water run-off on a global scale. Rivers could be clustered on the basis of seasonal variations in their isotope composition and latitude. Results showed furthermore, that there were periodic phases within each of these groupings and additional modelling exercises allowed a priori prediction of the seasonal variability as well as the isotopic composition of stable water isotopes in rivers. This predictive capacity will help to improve existing and new sampling strategies, help to validate and interpret riverine isotope data, and identify important catchment processes. Hence, the IAEA promulgates and supports longterm hydrological isotope observation networks and the application of isotope studies complementary with conventional hydrological, water quality, and ecological studies. (author)

  17. Integrating genome-based informatics to modernize global disease monitoring, information sharing, and response

    Aarestrup, Frank Møller; Brown, Eric W; Detter, Chris

    2012-01-01

    The rapid advancement of genome technologies holds great promise for improving the quality and speed of clinical and public health laboratory investigations and for decreasing their cost. The latest generation of genome DNA sequencers can provide highly detailed and robust information on disease...... typing methods to provide point-of-care clinical diagnosis and other essential information for quicker and better treatment of patients. Provided there is free-sharing of information by all clinical and public health laboratories, these genomic tools could spawn a global system of linked databases......-causing microbes, and in the near future these technologies will be suitable for routine use in national, regional, and global public health laboratories. With additional improvements in instrumentation, these next- or third-generation sequencers are likely to replace conventional culture-based and molecular...

  18. Integrated Marketing Strategies of German Companies : Start-Ups vs. Global Brands

    Kostin, Irina

    2016-01-01

    The purpose of this bachelor's thesis is to find out and analyze different marketing strategies of German fashion companies. The main part is comparing relatively young start-up companies to established companies and analyzing to what extent the strategies differ. The methodology used in this paper were semi-structured expert interviews with German start-up companies. The results were analyzed and compared to the secondary research on the big global German companies. The findings showed that ...

  19. Integration of Extended MHD and Kinetic Effects in Global Magnetosphere Models

    Germaschewski, K.; Wang, L.; Maynard, K. R. M.; Raeder, J.; Bhattacharjee, A.

    2015-12-01

    Computational models of Earth's geospace environment are an important tool to investigate the science of the coupled solar-wind -- magnetosphere -- ionosphere system, complementing satellite and ground observations with a global perspective. They are also crucial in understanding and predicting space weather, in particular under extreme conditions. Traditionally, global models have employed the one-fluid MHD approximation, which captures large-scale dynamics quite well. However, in Earth's nearly collisionless plasma environment it breaks down on small scales, where ion and electron dynamics and kinetic effects become important, and greatly change the reconnection dynamics. A number of approaches have recently been taken to advance global modeling, e.g., including multiple ion species, adding Hall physics in a Generalized Ohm's Law, embedding local PIC simulations into a larger fluid domain and also some work on simulating the entire system with hybrid or fully kinetic models, the latter however being to computationally expensive to be run at realistic parameters. We will present an alternate approach, ie., a multi-fluid moment model that is derived rigorously from the Vlasov-Maxwell system. The advantage is that the computational cost remains managable, as we are still solving fluid equations. While the evolution equation for each moment is exact, it depends on the next higher-order moment, so that truncating the hiearchy and closing the system to capture the essential kinetic physics is crucial. We implement 5-moment (density, momentum, scalar pressure) and 10-moment (includes pressure tensor) versions of the model, and use local approximations for the heat flux to close the system. We test these closures by local simulations where we can compare directly to PIC / hybrid codes, and employ them in global simulations using the next-generation OpenGGCM to contrast them to MHD / Hall-MHD results and compare with observations.

  20. Human motion simulation predictive dynamics

    Abdel-Malek, Karim

    2013-01-01

    Simulate realistic human motion in a virtual world with an optimization-based approach to motion prediction. With this approach, motion is governed by human performance measures, such as speed and energy, which act as objective functions to be optimized. Constraints on joint torques and angles are imposed quite easily. Predicting motion in this way allows one to use avatars to study how and why humans move the way they do, given specific scenarios. It also enables avatars to react to infinitely many scenarios with substantial autonomy. With this approach it is possible to predict dynamic motion without having to integrate equations of motion -- rather than solving equations of motion, this approach solves for a continuous time-dependent curve characterizing joint variables (also called joint profiles) for every degree of freedom. Introduces rigorous mathematical methods for digital human modelling and simulation Focuses on understanding and representing spatial relationships (3D) of biomechanics Develops an i...

  1. Global optimization for integrated design and control of computationally expensive process models

    Egea, J.A.; Vries, D.; Alonso, A.A.; Banga, J.R.

    2007-01-01

    The problem of integrated design and control optimization of process plants is discussed in this paper. We consider it as a nonlinear programming problem subject to differential-algebraic constraints. This class of problems is frequently multimodal and "costly" (i.e., computationally expensive to

  2. Decomposing passenger transport futures : Comparing results of global integrated assessment models

    Edelenbosch, O. Y.; McCollum, D. L.; van Vuuren, Detlef; Bertram, C.; Carrara, S.; Daly, H.; Fujimori, S.; Kitous, A.; Kyle, P.; Ó Broin, E.; Karkatsoulis, P.; Sano, F.

    The transport sector is growing fast in terms of energy use and accompanying greenhouse gas emissions. Integrated assessment models (IAMs) are used widely to analyze energy system transitions over a decadal time frame to help inform and evaluating international climate policy. As part of this, IAMs

  3. Direct experimental visualization of the global Hamiltonian progression of two-dimensional Lagrangian flow topologies from integrable to chaotic state

    Baskan, O.; Clercx, H. J. H [Fluid Dynamics Laboratory, Department of Applied Physics, Eindhoven University of Technology, P.O. Box 513, 5600 MB Eindhoven (Netherlands); Speetjens, M. F. M. [Energy Technology Laboratory, Department of Mechanical Engineering, Eindhoven University of Technology, P.O. Box 513, 5600 MB Eindhoven (Netherlands); Metcalfe, G. [Commonwealth Scientific and Industrial Research Organisation, Melbourne, Victoria 3190 (Australia); Swinburne University of Technology, Department of Mechanical Engineering, Hawthorn VIC 3122 (Australia)

    2015-10-15

    Countless theoretical/numerical studies on transport and mixing in two-dimensional (2D) unsteady flows lean on the assumption that Hamiltonian mechanisms govern the Lagrangian dynamics of passive tracers. However, experimental studies specifically investigating said mechanisms are rare. Moreover, they typically concern local behavior in specific states (usually far away from the integrable state) and generally expose this indirectly by dye visualization. Laboratory experiments explicitly addressing the global Hamiltonian progression of the Lagrangian flow topology entirely from integrable to chaotic state, i.e., the fundamental route to efficient transport by chaotic advection, appear non-existent. This motivates our study on experimental visualization of this progression by direct measurement of Poincaré sections of passive tracer particles in a representative 2D time-periodic flow. This admits (i) accurate replication of the experimental initial conditions, facilitating true one-to-one comparison of simulated and measured behavior, and (ii) direct experimental investigation of the ensuing Lagrangian dynamics. The analysis reveals a close agreement between computations and observations and thus experimentally validates the full global Hamiltonian progression at a great level of detail.

  4. Direct experimental visualization of the global Hamiltonian progression of two-dimensional Lagrangian flow topologies from integrable to chaotic state.

    Baskan, O; Speetjens, M F M; Metcalfe, G; Clercx, H J H

    2015-10-01

    Countless theoretical/numerical studies on transport and mixing in two-dimensional (2D) unsteady flows lean on the assumption that Hamiltonian mechanisms govern the Lagrangian dynamics of passive tracers. However, experimental studies specifically investigating said mechanisms are rare. Moreover, they typically concern local behavior in specific states (usually far away from the integrable state) and generally expose this indirectly by dye visualization. Laboratory experiments explicitly addressing the global Hamiltonian progression of the Lagrangian flow topology entirely from integrable to chaotic state, i.e., the fundamental route to efficient transport by chaotic advection, appear non-existent. This motivates our study on experimental visualization of this progression by direct measurement of Poincaré sections of passive tracer particles in a representative 2D time-periodic flow. This admits (i) accurate replication of the experimental initial conditions, facilitating true one-to-one comparison of simulated and measured behavior, and (ii) direct experimental investigation of the ensuing Lagrangian dynamics. The analysis reveals a close agreement between computations and observations and thus experimentally validates the full global Hamiltonian progression at a great level of detail.

  5. First series of total robotic hysterectomy (TRH) using new integrated table motion for the da Vinci Xi: feasibility, safety and efficacy.

    Giannini, Andrea; Russo, Eleonora; Mannella, Paolo; Palla, Giulia; Pisaneschi, Silvia; Cecchi, Elena; Maremmani, Michele; Morelli, Luca; Perutelli, Alessandra; Cela, Vito; Melfi, Franca; Simoncini, Tommaso

    2017-08-01

    To present the first case series of total robotic hysterectomy (TRH), using integrated table motion (ITM), which is a new feature comprising a unique operating table by Trumpf Medical that communicates wirelessly with the da Vinci Xi surgical system. ITM has been specifically developed to improve multiquadrant robotic surgery such as that conducted in colorectal surgery. Between May and October 2015, a prospective post-market study was conducted on ITM in the EU in 40 cases from different specialties. The gynecological study group comprised 12 patients. Primary endpoints were ITM feasibility, safety and efficacy. Ten patients underwent TRH. Mean number of ITM moves was three during TRH; there were 31 instances of table moves in the ten procedures. Twenty-eight of 31 ITM moves were made to gain internal exposure. The endoscope remained inserted during 29 of the 31 table movements (94%), while the instruments remained inserted during 27 of the 31 moves (87%). No external instrument collisions or other problems related to the operating table were noted. There were no ITM safety-related observations and no adverse events. This preliminary study demonstrated the feasibility, safety and efficacy of ITM for the da Vinci Xi surgical system in TRH. ITM was safe, with no adverse events related to its use. Further studies will be useful to define the real role and potential benefit of ITM in gynecological surgery.

  6. Exploiting Performance of Different Low-Cost Sensors for Small Amplitude Oscillatory Motion Monitoring: Preliminary Comparisons in View of Possible Integration

    Elisa Benedetti

    2016-01-01

    Full Text Available We address the problem of low amplitude oscillatory motion detection through different low-cost sensors: a LIS3LV02DQ MEMS accelerometer, a Microsoft Kinect v2 range camera, and a uBlox 6 GPS receiver. Several tests were performed using a one-direction vibrating table with different oscillation frequencies (in the range 1.5–3 Hz and small challenging amplitudes (0.02 m and 0.03 m. A Mikrotron EoSens high-resolution camera was used to give reference data. A dedicated software tool was developed to retrieve Kinect v2 results. The capabilities of the VADASE algorithm were employed to process uBlox 6 GPS receiver observations. In the investigated time interval (in the order of tens of seconds the results obtained indicate that displacements were detected with the resolution of fractions of millimeters with MEMS accelerometer and Kinect v2 and few millimeters with uBlox 6. MEMS accelerometer displays the lowest noise but a significant bias, whereas Kinect v2 and uBlox 6 appear more stable. The results suggest the possibility of sensor integration both for indoor (MEMS accelerometer + Kinect v2 and for outdoor (MEMS accelerometer + uBlox 6 applications and seem promising for structural monitoring applications.

  7. Korea’s Trade Strategies for Mega Free Trade Agreements in Regional and Global Economic Integration

    Sang-Chul Park

    2016-12-01

    Full Text Available Korea has developed rapidly since the 1960s. It is one of the four Asian tiger economies and a good model for developing countries. Korea shows the world how a developing country can develop its economy rapidly and become industrialized. Its development strategy has mainly been an export-oriented trade policy. As a result, its trade volume grew from $1 billion in 1966 to $1 trillion in 2011, which is a 1,000-fold increase within five decades. Since 2011, Korea has become one of seven countries with a trade volume over $1 trillion. However, the Korean economy has experienced turbulence as well as positive growth. It underwent severe economic crises such as the Asian financial crisis in 1997 and the global financial crisis in 2008. Its economy has been extremely vulnerable to the external economic environment, although it has improved and strengthened, particularly since the global financial crisis. During those two crises, the government carried out an appropriate trade policy with a strategic approach to upgrade its industrial structure and competitiveness in global markets. This article comprehensively discusses Korean trade policy and strategy over the last five decades, and how its national economy has developed rapidly. It also explores how the government sets its strategic targets in Asia and the Asia Pacific region. It considers two mega free trade agreements (FTAs — the Regional Comprehensive Economic Partnership and the Trans-Pacific Partnership — as new opportunities for further development. Therefore, it is wise to analyze these regional mega FTAs in order to maximize the national interest.

  8. Marginalization: A Revisitation With Integration of Scholarship on Globalization, Intersectionality, Privilege, Microaggressions, and Implicit Biases.

    Hall, Joanne M; Carlson, Kelly

    2016-01-01

    In 1994, the concept of marginalization was explored in an article in Advances in Nursing Science. This is a revisitation of the concept incorporating new scholarship. This update is founded on feminism, postcolonialism, critical race theory, and discourse deconstruction, all viewpoints that have been explicated in nursing. The purpose of this analysis is to look at new scholarship and concepts useful to applying marginalization in nursing knowledge development from the standpoint of Bourdieu's macro, meso, and micro levels. New scholarship includes globalization, intersectionality, privilege, microaggressions, and implicit bias. Implications for decreasing health disparities through this new scholarship are discussed.

  9. Analysis of global warming stabilization scenarios. The Asian-Pacific Integrated Model

    Kainuma, Mikiko; Morita, Tsuneyuki; Masui, Toshihiko; Takahashi, Kiyoshi; Matsuoka, Yuzuru

    2004-01-01

    This paper analyzes the economic and climatic impacts of the EMF 19 emission scenarios. A reference scenario, three emission scenarios targeting 550 ppmv atmospheric concentration, and three tax scenarios are analyzed. The profiles of energy consumption and economic losses of each policy scenario are compared to the reference scenario. The model also estimates that global mean temperature will increase 1.7-2.9 C in 2100, and the sea level will rise 40-51 cm, compared to the 1990 levels under the EMF scenarios. Impacts on food productivity and malaria infection are estimated to be very severe in some countries in the Asian region

  10. Integrated assessment of global water scarcity over the 21st century - Part 2: Climate change mitigation policies

    Hejazi, M. I.; Edmonds, J.; Clarke, L.; Kyle, P.; Davies, E.; Chaturvedi, V.; Eom, J.; Wise, M.; Patel, P.; Calvin, K.

    2013-03-01

    We investigate the effects of emission mitigation policies on water scarcity both globally and regionally using the Global Change Assessment Model (GCAM), a leading community integrated assessment model of energy, agriculture, climate, and water. Three climate policy scenarios with increasing mitigation stringency of 7.7, 5.5, and 4.2 W m-2 in year 2095 (equivalent to the SRES A2, B2, and B1 emission scenarios, respectively), under two carbon tax regimes (a universal carbon tax (UCT) which includes land use change emissions, and a fossil fuel and industrial emissions carbon tax (FFICT) which excludes land use change emissions) are analyzed. The results are compared to a baseline scenario (i.e. no climate change mitigation policy) with radiative forcing reaching 8.8 W m-2 (equivalent to the SRES A1Fi emission scenario) by 2095. When compared to the baseline scenario and maintaining the same baseline socioeconomic assumptions, water scarcity declines under a UCT mitigation policy but increases with a FFICT mitigation scenario by the year 2095 particularly with more stringent climate mitigation targets. The decreasing trend with UCT policy stringency is due to substitution from more water-intensive to less water-intensive choices in food and energy production, and in land use. Under the FFICT scenario, water scarcity is projected to increase driven by higher water demands for bio-energy crops. This study implies an increasingly prominent role for water availability in future human decisions, and highlights the importance of including water in integrated assessment of global change. Future research will be directed at incorporating water shortage feedbacks in GCAM to better understand how such stresses will propagate across the various human and natural systems in GCAM.

  11. Rotational Motion Control of a Spacecraft

    Wisniewski, Rafal; Kulczycki, P.

    2001-01-01

    The paper adopts the energy shaping method to control of rotational motion. A global representation of the rigid body motion is given in the canonical form by a quaternion and its conjugate momenta. A general method for motion control on a cotangent bundle to the 3-sphere is suggested. The design...... algorithm is validated for three-axis spacecraft attitude control...

  12. Rotational motion control of a spacecraft

    Wisniewski, Rafal; Kulczycki, P.

    2003-01-01

    The paper adopts the energy shaping method to control of rotational motion. A global representation of the rigid body motion is given in the canonical form by a quaternion and its conjugate momenta. A general method for motion control on a cotangent bundle to the 3-sphere is suggested. The design...... algorithm is validated for three-axis spacecraft attitude control. Udgivelsesdato: APR...

  13. Global nuclear material monitoring with NDA and C/S data through integrated facility monitoring

    Howell, J.A.; Menlove, H.O.; Argo, P.; Goulding, C.; Klosterbuer, S.; Halbig, J.

    1996-01-01

    This paper focuses on a flexible, integrated demonstration of a monitoring approach for nuclear material monitoring. This includes aspects of item signature identification, perimeter portal monitoring, advanced data analysis, and communication as a part of an unattended continuous monitoring system in an operating nuclear facility. Advanced analysis is applied to the integrated nondestructive assay and containment and surveillance data that are synchronized in time. End result will be the foundation for a cost-effective monitoring system that could provide the necessary transparency even in areas that are denied to foreign nationals of both US and Russia should these processes and materials come under full-scope safeguards or bilateral agreements. Monitoring systems of this kind have the potential to provide additional benefits including improved nuclear facility security and safeguards and lower personnel radiation exposures. Demonstration facilities in this paper include VTRAP-prototype, Los Alamos Critical Assemblies Facility, Kazakhstan BM-350 Reactor monitor, DUPIC radiation monitoring, and JOYO and MONJU radiation monitoring

  14. [Integrated Management Area of Vascular Risk: A new organisational model for global control of risk factors].

    Armario, P; Jericó, C; Vila, L; Freixa, R; Martin-Castillejos, C; Rotllan, M

    Cardiovascular disease (CVD), is a major cause of morbidity and mortality that increases the cost of care. Currently there is a low degree of control of the main cardiovascular risk factors, although we have a good therapeutic arsenal. To achieve the improvement of this reality, a good coordination and multidisciplinary participation are essential. The development of new organizational models such as the Integrated Management Area of Vascular Risk can facilitate the therapeutic harmonization and unification of the health messages offered by different levels of care, based on clinical practice guidelines, in order to provide patient-centred integrated care. Copyright © 2016 SEH-LELHA. Publicado por Elsevier España, S.L.U. All rights reserved.

  15. Global Principle of Ecological Integrity and its Implementation in Management of the Czech Landscape

    Cudlínová, Eva; Lapka, Miloslav; Líšková, Zuzana

    2005-01-01

    Roč. 24, č. 1 (2005), s. 89-107 ISSN 1335-342X R&D Projects: GA MŠk(CZ) ME 530; GA MŽP(CZ) SM/640/18/03 Grant - others:EU GOCE-CT-2003-505297-MULTAGRI Institutional research plan: CEZ:AV0Z60870520 Keywords : ecological integrity * landscape * typology * category Subject RIV: AO - Sociology, Demography Impact factor: 0.085, year: 2005

  16. On the existence of global strong solutions to the equations modeling a motion of a rigid body around a viscous fluid

    Nečasová, Šárka; Wolf, J.

    2016-01-01

    Roč. 36, č. 3 (2016), s. 1539-1562 ISSN 1078-0947 R&D Projects: GA ČR GA13-00522S Institutional support: RVO:67985840 Keywords : incompressible fluid * motion of rigid body * strong solutions Subject RIV: BA - General Mathematics Impact factor: 1.099, year: 2016 http://www.aimsciences.org/journals/displayArticlesnew.jsp?paperID=11589

  17. A comparison of integrated river basin management strategies: A global perspective

    Zhao, Chunhong; Wang, Pei; Zhang, Guanghong

    In order to achieve the integrated river basin management in the arid and rapid developing region, the Heihe River Basin (HRB) in Northwestern China, one of critical river basins were selected as a representative example, while the Murray-Darling Basin (MDB) in Australia and the Colorado River Basin (CRB) in the USA were selected for comparative analysis in this paper. Firstly, the comparable characters and hydrological contexts of these three watersheds were introduced in this paper. Then, based on comparative studies on the river basin challenges in terms of the drought, intensive irrigation, and rapid industrialization, the hydrological background of the MDB, the CRB and the HRB was presented. Subsequently, the river management strategies were compared in three aspects: water allocation, water organizations, and water act and scientific projects. Finally, we proposed recommendations for integrated river basin management for the HRB: (1) Water allocation strategies should be based on laws and markets on the whole basin; (2) Public participation should be stressed by the channels between governance organizations and local communities; (3) Scientific research should be integrated into river management to understand the interactions between the human and nature.

  18. Global electricity transformation: The critical need for integrated market design and risk management research

    Hung-po Chao

    2006-01-01

    The past three decades transformed the electricity industry. The essential goals of liberalization have been to lower costs, improve reliability, and stimulate investment and innovations through establishment of competitive electricity markets, while also relying on market mechanisms to provide creative solutions to environmental and security problems. In many instances, these goals have been achieved, but the occurrence of some spectacular market failures have brought into question the whole restructuring effort. This paper reviews recent experiences with market reform and concludes that a significant cause of failure has been the rush to unbundle vertically integrated utilities without sufficient consideration of alternative ways to manage the risk of electricity market restructuring. In particular, there is a critical need for integrated market design and risk management research to improve the process of market transformation by taking a more evolutionary approach to discover a 'Third Way' above vertical integration and full unbundling. Such research can offer a crucial feedback link to the restructuring process by identifying important lessons to be learned from past experience and developing new analytical tools to help introduce more successful market designs for the future. (author)

  19. Periodicity and quasi-periodicity for super-integrable hamiltonian systems

    Kibler, M.; Winternitz, P.

    1990-01-01

    Classical trajectories are calculated for two Hamiltonian systems with ring shaped potentials. Both systems are super-integrable, but not maximally super-integrable, having four globally defined single-valued integrals of motion each. All finite trajectories are quasi-periodical; they become truly periodical if a commensurability condition is imposed on an angular momentum component

  20. Integrated assessment of global water scarcity over the 21st century under multiple climate change mitigation policies

    Hejazi, Mohamad I.; Edmonds, James A.; Clarke, Leon E.; Kyle, G. Page; Davies, Evan; Chaturvedi, Vaibhav; Wise, Marshall A.; Patel, Pralit L.; Eom, Jiyong; Calvin, Katherine V.

    2014-08-01

    Water scarcity conditions over the 21st century both globally and regionally are assessed in the context of climate change and climate mitigation policies, by estimating both water availability and water demand within the Global Change Assessment Model (GCAM), a leading community integrated assessment model of energy, agriculture, climate, and water. To quantify changes in future water availability, a new gridded water-balance global hydrologic model – namely, the Global Water Availability Model (GWAM) – is developed and evaluated. Global water demands for six major demand sectors (irrigation, livestock, domestic, electricity generation, primary energy production, and manufacturing) are modeled in GCAM at the regional scale (14 geopolitical regions, 151 sub-regions) and then spatially downscaled to 0.5 o x 0.5o resolution to match the scale of GWAM. Using a baseline scenario (i.e., no climate change mitigation policy) with radiative forcing reaching 8.8 W/m2 (equivalent to the SRES A1Fi emission scenario) and three climate policy scenarios with increasing mitigation stringency of 7.7, 5.5, and 4.2 W/m2 (equivalent to the SRES A2, B2, and B1 emission scenarios, respectively), we investigate the effects of emission mitigation policies on water scarcity. Two carbon tax regimes (a universal carbon tax (UCT) which includes land use change emissions, and a fossil fuel and industrial emissions carbon tax (FFICT) which excludes land use change emissions) are analyzed. The baseline scenario results in more than half of the world population living under extreme water scarcity by the end of the 21st century. Additionally, in years 2050 and 2095, 36% (28%) and 44% (39%) of the global population, respectively, is projected to live in grid cells (in basins) that will experience greater water demands than the amount of available water in a year (i.e., the water scarcity index (WSI) > 1.0). When comparing the climate policy scenarios to the baseline scenario while maintaining

  1. In vitro analysis of integrated global high-resolution DNA methylation profiling with genomic imbalance and gene expression in osteosarcoma.

    Bekim Sadikovic

    Full Text Available Genetic and epigenetic changes contribute to deregulation of gene expression and development of human cancer. Changes in DNA methylation are key epigenetic factors regulating gene expression and genomic stability. Recent progress in microarray technologies resulted in developments of high resolution platforms for profiling of genetic, epigenetic and gene expression changes. OS is a pediatric bone tumor with characteristically high level of numerical and structural chromosomal changes. Furthermore, little is known about DNA methylation changes in OS. Our objective was to develop an integrative approach for analysis of high-resolution epigenomic, genomic, and gene expression profiles in order to identify functional epi/genomic differences between OS cell lines and normal human osteoblasts. A combination of Affymetrix Promoter Tilling Arrays for DNA methylation, Agilent array-CGH platform for genomic imbalance and Affymetrix Gene 1.0 platform for gene expression analysis was used. As a result, an integrative high-resolution approach for interrogation of genome-wide tumour-specific changes in DNA methylation was developed. This approach was used to provide the first genomic DNA methylation maps, and to identify and validate genes with aberrant DNA methylation in OS cell lines. This first integrative analysis of global cancer-related changes in DNA methylation, genomic imbalance, and gene expression has provided comprehensive evidence of the cumulative roles of epigenetic and genetic mechanisms in deregulation of gene expression networks.

  2. Emergence of long distance bird migrations: a new model integrating global climate changes

    Louchart, Antoine

    2008-12-01

    During modern birds history, climatic and environmental conditions have evolved on wide scales. In a continuously changing world, landbirds annual migrations emerged and developed. However, models accounting for the origins of these avian migrations were formulated with static ecogeographic perspectives. Here I reviewed Cenozoic paleoclimatic and paleontological data relative to the palearctic paleotropical long distance (LD) migration system. This led to propose a new model for the origin of LD migrations, the ‘shifting home’ model (SHM). It is based on a dynamic perspective of climate evolution and may apply to the origins of most modern migrations. Non-migrant tropical African bird taxa were present at European latitudes during most of the Cenozoic. Their distribution limits shifted progressively toward modern tropical latitudes during periods of global cooling and increasing seasonality. In parallel, decreasing winter temperatures in the western Palearctic drove shifts of population winter ranges toward the equator. I propose that this induced the emergence of most short distance migrations, and in turn LD migrations. This model reconciliates ecologically tropical ancestry of most LD migrants with predominant winter range shifts, in accordance with requirements for heritable homing. In addition, it is more parsimonious than other non-exclusive models. Greater intrinsic plasticity of winter ranges implied by the SHM is supported by recently observed impacts of the present global warming on migrating birds. This may induce particular threats to some LD migrants. The ancestral, breeding homes of LD migrants were not ‘northern’ or ‘southern’ but shifted across high and middle latitudes while migrations emerged through winter range shifts themselves.

  3. An Assessment Tool to Integrate Sustainability Principles into the Global Supply Chain

    María Jesús Muñoz-Torres

    2018-02-01

    Full Text Available The integration of sustainability principles into the assessment of companies along the supply chains is a growing research area. However, there is an absence of a generally accepted method to evaluate corporate sustainability performance (CSP, and the models and frameworks proposed by the literature present various important challenges to be addressed. A systematic literature review on the supply chain at the corporate level has been conducted, analyzing the main strengths and gaps in the sustainability assessment literature. Therefore, this paper aims to contribute to the development of this field by proposing an assessment framework a leading company can adopt to expand sustainability principles to the rest of the members of the supply chain. This proposal is based on best practices and integrates and shares efforts with key initiatives (for instance, the Organizational Environmental Footprint from the European Commission and United Nations Environment Programme and the Society of Environmental Toxicology and Chemistry UNEP/SETAC; moreover, it overcomes important limitations of the current sustainability tools in a supply chain context consistent with the circular economy, the Sustainable Development Goals (SDGs, planetary boundaries, and social foundation requirements. The results obtained create, on the one hand, new opportunities for academics; and, on the other hand, in further research, the use of this framework could be a means of actively engaging companies in their supply chains and of achieving the implementation of practical and comprehensive CSP assessment.

  4. Integrated Strategic Planning of Global Production Networks and Financial Hedging under Uncertain Demands and Exchange Rates

    Achim Koberstein

    2013-11-01

    Full Text Available In this paper, we present a multi-stage stochastic programming model that integrates financial hedging decisions into the planning of strategic production networks under uncertain exchange rates and product demands. This model considers the expenses of production plants and the revenues of markets in different currency areas. Financial portfolio planning decisions for two types of financial instruments, forward contracts and options, are represented explicitly by multi-period decision variables and a multi-stage scenario tree. Using an illustrative example, we analyze the impact of exchange-rate and demand volatility, the level of investment expenses and interest rate spreads on capacity location and dimensioning decisions. In particular, we show that, in the illustrative example, the exchange-rate uncertainty cannot be completely eliminated by financial hedging in the presence of demand uncertainty. In this situation, we find that the integrated model can result in better strategic planning decisions for a risk-averse decision maker compared to traditional modeling approaches.

  5. Overview of past, ongoing and future efforts of the integrated modeling of global change for Northern Eurasia

    Monier, Erwan; Kicklighter, David; Sokolov, Andrei; Zhuang, Qianlai; Melillo, Jerry; Reilly, John

    2016-04-01

    Northern Eurasia is both a major player in the global carbon budget (it includes roughly 70% of the Earth's boreal forest and more than two-thirds of the Earth's permafrost) and a region that has experienced dramatic climate change (increase in temperature, growing season length, floods and droughts) over the past century. Northern Eurasia has also undergone significant land-use change, both driven by human activity (including deforestation, expansion of agricultural lands and urbanization) and natural disturbances (such as wildfires and insect outbreaks). These large environmental and socioeconomic impacts have major implications for the carbon cycle in the region. Northern Eurasia is made up of a diverse set of ecosystems that range from tundra to forests, with significant areas of croplands and pastures as well as deserts, with major urban areas. As such, it represents a complex system with substantial challenges for the modeling community. In this presentation, we provide an overview of past, ongoing and possible future efforts of the integrated modeling of global change for Northern Eurasia. We review the variety of existing modeling approaches to investigate specific components of Earth system dynamics in the region. While there are a limited number of studies that try to integrate various aspects of the Earth system (through scale, teleconnections or processes), we point out that there are few systematic analyses of the various feedbacks within the Earth system (between components, regions or scale). As a result, there is a lack of knowledge of the relative importance of such feedbacks, and it is unclear how policy relevant current studies are that fail to account for these feedbacks. We review the role of Earth system models, and their advantages/limitations compared to detailed single component models. We further introduce the human activity system (global trade, economic models, demographic model and so on), the need for coupled human/earth system models

  6. The Educated Citizen and Global Public-Health Issues: One Model for Integration into the Undergraduate Curriculum.

    Caron, Rosemary M

    2016-01-01

    The Educated Citizen Initiative proposes that an understanding of public-health issues is a core component of an educated citizenry and is essential to develop one's societal responsibility. This initiative supports the Institute of Medicine's recommendation that "all undergraduates should have access to education in public health." Furthermore, the Liberal Education and America's Promise (LEAP) framework developed by the Association of American Colleges and Universities supports the "integration of public-health education into general and liberal education with an aim to produce an educated citizenry." The LEAP framework is implemented by teaching about the role of social determinants in a population's health status; the significance of personal and social responsibility; and providing skills for inquiry, critical thinking, problem solving, and evaluation. This article describes one university's experience in generating an educated citizenry cognizant of comprehensive public-health conflicts, thus contributing to both a local and global perspective on learning.

  7. Semi-automatic detection and correction of body organ motion, particularly cardiac motion in SPECT studies

    Quintana, J.C.; Caceres, F.; Vargas, P.

    2002-01-01

    Aim: Detect patient motion during SPECT imaging. Material and Method: SPECT study is carried out on a patient's body organ, such as the heart, and frame of image data are thereby acquired. The image data in these frames are subjected to a series of mappings and computations, from which frame containing a significant quantity of organ motion can be identified. Quantification of motion occurs by shifting some of the mapped data within a predetermined range, and selecting that data shift which minimizes the magnitude of a motion sensitive mathematical function. The sensitive mathematical function is constructed from all set of image frames using the pixel data within a region covering the body organ. Using cine display of planar image data, the operator defines the working region by marking two points, which define two horizontal lines covering the area of the body organ. This is the only operator intervention. The mathematical function integrates pixel data from all set of image frames and therefore does not use derivatives which may cause distortion in noisy data. Moreover, as a global function, this method is superior than that using frame-to-frame cross-correlation function to identify motion between adjacent frames. Using standard image processing software, the method was implemented computationally. Ten SPECT studies with movement (Sestamibi cardiac studies and 99m-ECD brain SPECT studies) were selected plus two others with no movement. The acquisition SPECT protocol for the cardiac study was as follow: Step and shoot mode, non-circular orbit, 64 stops 20s each, 64x64x16 matrix and LEHR colimator. For the brain SPECT, 128 stops over 360 0 were used. Artificial vertical displacements (±1-2 pixels) over several frames were introduced in those studies with no movement to simulate patient motion. Results: The method was successfully tested in all cases and was capable to recognize SPECT studies with no body motion as well as those with body motion (both from the

  8. Integration of UAV and ground-based Structure from Motion with Multi-View Stereo photogrammetry and hydrological data to quantify hillslope gully erosion processes in tropical savanna

    Koci, J.; Jarihani, B.; Sidle, R. C.; Wilkinson, S. N.; Bartley, R.

    2017-12-01

    Structure from Motion with Multi-View Stereo (SfM-MVS) photogrammetry provides a cost-effective method of rapidly acquiring high resolution (sub-meter) topographic data, but is rarely used in hydrogeomorphic investigations of gully erosion. This study integrates high resolution topographic and land cover data derived from an unmanned aerial vehicle (UAV) and ground-based SfM-MVS photogrammetry, with rainfall and gully discharge data, to elucidate hydrogeomorphic processes driving hillslope gully erosion. The study is located within a small (13 km2) dry-tropical savanna catchment within the Burdekin River Basin, northeast Australia, which is a major contributor sediments and nutrients to the Great Barrier Reef World Heritage Area. A pre-wet season UAV survey covered an entire hillslope gully system (0.715 km2), and is used to derive topography, ground cover and hydrological flow pathways in the gully contributing area. Ground-based surveys of a single active gully (650 m2) within the broader hillslope are compared between pre- and post-wet season conditions to quantify gully geomorphic change. Rainfall, recorded near to the head of the gully, is related to gully discharge during sporadic storm events. The study provides valuable insights into the relationships among hydrological flow pathways, ground cover, rainfall and runoff, and spatial patterns of gully morphologic change. We demonstrate how UAV and ground-based SfM-MVS photogrammetry can be used to improve hydrogeomorphic process understanding and aid in the modelling and management of hillslope gully systems.

  9. Cosmic global strings

    Sikivie, P.

    1991-01-01

    The topics are: global strings; the gravitational field of a straight global string; how do global strings behave?; the axion cosmological energy density; computer simulations of the motion and decay of global strings; electromagnetic radiation from the conversion of Nambu-Goldstone bosons in astrophysical magnetic fields. (orig.)

  10. Welfare state, labour market inequalities and health. In a global context: an integrated framework. SESPAS report 2010.

    Muntaner, Carles; Benach, Joan; Chung, Haejoo; Edwin, N G; Schrecker, Ted

    2010-12-01

    Since the nineteen seventies, high- and low-income countries have undergone a pattern of transnational economic and cultural integration known as globalization. The weight of the available evidence suggests that the effects of globalization on labor markets have increased economic inequality and various forms of economic insecurity that negatively affect workers' health. Research on the relation between labor markets and health is hampered by the social invisibility of many of these health inequalities. Empirical evidence of the impact of employment relations on health inequalities is scarce for low-income countries, small firms, rural settings, and sectors of the economy in which "informality" is widespread. Information is also scarce on the effectiveness of labor market interventions in reducing health inequalities. This pattern is likely to continue in the future unless governments adopt active labor market policies. Such policies include creating jobs through state intervention, regulating the labor market to protect employment, supporting unions, and ensuring occupational safety and health standards. Copyright © 2010 SESPAS. Published by Elsevier Espana. All rights reserved.

  11. Assessing the Benefits of Global Climate Stabilization Within an Integrated Modeling Framework

    Beach, R. H.

    2015-12-01

    Increasing atmospheric carbon dioxide levels, higher temperatures, altered precipitation patterns, and other climate change impacts have already begun to affect US agriculture and forestry, with impacts expected to become more substantial in the future. There have been a number of studies of climate change impacts on agriculture or forestry. However, relatively few studies explore climate change impacts on both agriculture and forests simultaneously, including the interactions between alternative land uses and implications for market outcomes. Additionally, there is a lack of detailed analyses of the effects of stabilization scenarios relative to unabated emissions scenarios. Such analyses are important for developing estimates of the benefits of those stabilization scenarios, which can play a vital role in assessing tradeoffs associated with allocating resources across alternative mitigation and adaptation activities. We provide an analysis of the potential benefits of global climate change mitigation for US agriculture and forestry through 2100, accounting for landowner decisions regarding land use, crop mix, and management practices. The analytic approach involves a combination of climate models, a crop process model (EPIC), a dynamic vegetation model used for forests (MC1), and an economic model of the US forestry and agricultural sector (FASOM-GHG). We find substantial impacts on productivity, commodity markets, and consumer and producer welfare for the stabilization scenario relative to unabated climate change, though the magnitude and direction of impacts vary across regions and commodities. Although there is variability in welfare impacts across climate simulations, we find positive net benefits from stabilization in all cases, with cumulative impacts ranging from 32.7 billion to 54.5 billion over the period 2015-2100. Our estimates contribute to the literature on potential benefits of GHG mitigation and can help inform policy decisions weighing alternative

  12. Dirt: Integrating Scientific and Local Knowledge to Support Global Land Management

    Okin, G.; Herrick, J.; Bestelmeyer, B.; Hanan, N. P.; Neff, J. C.; Peters, D. P. C.; Sala, O.; Salley, S. W.; Vivoni, E. R.; Wills, S. A.

    2017-12-01

    "Dirt." "It's that elm shade, red rust clay you grew up on - That plowed up ground that your dad damned his luck on." We will draw on the first lines of the chorus from a song by Florida Georgia Line to explain how our collective research can provide insights to help prevent the next Dust Bowl, increase returns on investments in land restoration, and limit nutrient runoff to the Gulf of Mexico. Our presentation will show how we are supporting management decisions in New Mexico, Namibia and Mongolia by integrating NRCS soil survey information with an understanding of soil variability, and landscape patterns and dynamics developed at the Jornada LTER and USDA-ARS research unit, working with and drawing on related research from around the world. We will highlight work identifying wind erosion thresholds based on easily measured changes in vegetation structure. We will also demonstrate how landscape stratification by soils can be used to increase the probability of success of restoration treatments. We will end with a demonstration of a suite of mobile phone apps that are being developed to increase access to scientific knowledge by farmers, policymakers and natural resource managers around the world, and to allow them to contextualize and share their own soil-specific local knowledge. A co-benefit is the use as a crowd-sourcing tool.

  13. Exploring the Technological Collaboration Characteristics of the Global Integrated Circuit Manufacturing Industry

    Yun Liu

    2018-01-01

    Full Text Available With the intensification of international competition, there are many international technological collaborations in the integrated circuit manufacturing (ICM industry. The importance of improving the level of international technological collaboration is becoming more and more prominent. Therefore, it is vital for a country, a region, or an institution to understand the international technological collaboration characteristics of the ICM industry and, thus, to know how to enhance its own international technological collaboration. This paper depicts the international technological collaboration characteristics of the ICM industry based on patent analysis. Four aspects, which include collaboration patterns, collaboration networks, collaboration institutions, and collaboration impacts, are analyzed by utilizing patent association analysis and social network analysis. The findings include the following: first, in regard to international technological collaboration, the USA has the highest level, while Germany has great potential for future development; second, Asia and Europe have already formed clusters, respectively, in the cooperative network; last, but not least, research institutions, colleges, and universities should also actively participate in international collaboration. In general, this study provides an objective reference for policy making, competitiveness, and sustainability in the ICM industry. The framework presented in this paper could be applied to examine other industrial international technological collaborations.

  14. Improved motion description for action classification

    Jain, M.; Jégou, H.; Bouthemy, P.

    2016-01-01

    Even though the importance of explicitly integrating motion characteristics in video descriptions has been demonstrated by several recent papers on action classification, our current work concludes that adequately decomposing visual motion into dominant and residual motions, i.e., camera and scene

  15. Quality of Life Theory I. The IQOL Theory: An Integrative Theory of the Global Quality of Life Concept

    Soren Ventegodt

    2003-01-01

    Full Text Available Quality of life (QOL means a good life and we believe that a good life is the same as living a life with a high quality. This paper presents the theoretical and philosophical framework of the Danish Quality of Life Survey, and of the SEQOL, QOL5, and QOL1 questionnaires.The notion of a good life can be observed from subjective to the objective, where this spectrum incorporates a number of existing quality of life theories. We call this spectrum the integrative quality-of-life (IQOL theory and discuss the following aspects in this paper: well being, satisfaction with life, happiness, meaning in life, the biological information system (�balance�, realizing life potential, fulfillment of needs, and objective factors.The philosophy of life outlined in this paper tries to measure the global quality of life with questions derived from the integrative theory of the quality of life. The IQOL theory is an overall theory or meta-theory encompassing eight more factual theories in a subjective-existential-objective spectrum. Other philosophies of life can stress other aspects of life, but by this notion of introducing such an existential depth into the health and social sciences, we believe to have taken a necessary step towards a new humility and respect for the richness and complexity of life.

  16. WE-G-BRD-04: BEST IN PHYSICS (JOINT IMAGING-THERAPY): An Integrated Model-Based Intrafractional Organ Motion Tracking Approach with Dynamic MRI in Head and Neck Radiotherapy

    Chen, H; Dolly, S; Anastasio, M; Li, H; Wooten, H; Gay, H; Mutic, S; Thorstad, W; Li, H [Washington University School of Medicine, Saint Louis, MO (United States); Victoria, J; Dempsey, J [ViewRay incorporated, Oakwood Village, Ohio (United States); Ruan, S [University of Rouen, QuantIF - EA 4108 LITIS, Rouen (France); Low, D [Deparment of Radiation Oncology, University of California Los Angeles, Los Angeles, CA (United States)

    2015-06-15

    Purpose: In-treatment dynamic cine images, provided by the first commercially available MRI-guided radiotherapy system, allow physicians to observe intrafractional motion of head and neck (H&N) internal structures. Nevertheless, high anatomical complexity and relatively poor cine image contrast/resolution have complicated automatic intrafractional motion evaluation. We proposed an integrated model-based approach to automatically delineate and analyze moving structures from on-board cine images. Methods: The H&N upper airway, a complex and highly deformable region wherein severe internal motion often occurs, was selected as the target-to-be-tracked. To reliably capture its motion, a hierarchical structure model containing three statistical shapes (face, face-jaw, and face-jaw-palate) was first built from a set of manually delineated shapes using principal component analysis. An integrated model-fitting algorithm was then employed to align the statistical shapes to the first to-be-detected cine frame, and multi-feature level-set contour propagation was performed to identify the airway shape change in the remaining frames. Ninety sagittal cine MR image sets, acquired from three H&N cancer patients, were utilized to demonstrate this approach. Results: The tracking accuracy was validated by comparing the results to the average of two manual delineations in 20 randomly selected images from each patient. The resulting dice similarity coefficient (93.28+/−1.46 %) and margin error (0.49+/−0.12 mm) showed good agreement with the manual results. Intrafractional displacements of anterior, posterior, inferior, and superior airway boundaries were observed, with values of 2.62+/−2.92, 1.78+/−1.43, 3.51+/−3.99, and 0.68+/−0.89 mm, respectively. The H&N airway motion was found to vary across directions, fractions, and patients, and highly correlated with patients’ respiratory frequency. Conclusion: We proposed the integrated computational approach, which for the first

  17. WE-G-BRD-04: BEST IN PHYSICS (JOINT IMAGING-THERAPY): An Integrated Model-Based Intrafractional Organ Motion Tracking Approach with Dynamic MRI in Head and Neck Radiotherapy

    Chen, H; Dolly, S; Anastasio, M; Li, H; Wooten, H; Gay, H; Mutic, S; Thorstad, W; Li, H; Victoria, J; Dempsey, J; Ruan, S; Low, D

    2015-01-01

    Purpose: In-treatment dynamic cine images, provided by the first commercially available MRI-guided radiotherapy system, allow physicians to observe intrafractional motion of head and neck (H&N) internal structures. Nevertheless, high anatomical complexity and relatively poor cine image contrast/resolution have complicated automatic intrafractional motion evaluation. We proposed an integrated model-based approach to automatically delineate and analyze moving structures from on-board cine images. Methods: The H&N upper airway, a complex and highly deformable region wherein severe internal motion often occurs, was selected as the target-to-be-tracked. To reliably capture its motion, a hierarchical structure model containing three statistical shapes (face, face-jaw, and face-jaw-palate) was first built from a set of manually delineated shapes using principal component analysis. An integrated model-fitting algorithm was then employed to align the statistical shapes to the first to-be-detected cine frame, and multi-feature level-set contour propagation was performed to identify the airway shape change in the remaining frames. Ninety sagittal cine MR image sets, acquired from three H&N cancer patients, were utilized to demonstrate this approach. Results: The tracking accuracy was validated by comparing the results to the average of two manual delineations in 20 randomly selected images from each patient. The resulting dice similarity coefficient (93.28+/−1.46 %) and margin error (0.49+/−0.12 mm) showed good agreement with the manual results. Intrafractional displacements of anterior, posterior, inferior, and superior airway boundaries were observed, with values of 2.62+/−2.92, 1.78+/−1.43, 3.51+/−3.99, and 0.68+/−0.89 mm, respectively. The H&N airway motion was found to vary across directions, fractions, and patients, and highly correlated with patients’ respiratory frequency. Conclusion: We proposed the integrated computational approach, which for the first

  18. Integrated rice-duck farming decreases global warming potential and increases net ecosystem economic budget in central China.

    Sheng, Feng; Cao, Cou-Gui; Li, Cheng-Fang

    2018-05-31

    Over the past decades, many attempts have been made to assess the effects of integrated rice-duck farming on greenhouse gas emissions, use efficient of energy, soil fertility, and economic significance. However, very few studies have been focused on the effects of the farming on net ecosystem economic budget (NEEB). Here, a 2-year field experiment was conducted to comprehensively investigate the effects of ducks raised in paddy fields on CH 4 and N 2 O emissions, global warming potential (GWP), rice grain yield, and NEEB in central China. The experiment included two treatments: integrated rice-duck farming (RD) and conventional rice farming (R). The introduction of ducks into the paddy fields markedly increased the rice grain yield due to enhanced tiller number and root bleeding rate. RD treatment significantly elevated the N 2 O emissions (p < 0.05) but decreased CH 4 emissions (p < 0.05) during rice growing seasons compared with R treatment. Analysis of GWP based on CH 4 and N 2 O emissions showed that compared with R treatment, RD treatment significantly decreased the GWP by 28.1 and 28.0% and reduced the greenhouse gas intensity by 30.6 and 29.8% in 2009 and 2010, respectively. In addition, RD treatment increased NEEB by 40.8 and 39.7% respectively in 2009 and 2010 relative to R treatment. Taken together, our results suggest that the integrated rice-duck farming system is an effective strategy to optimize the economic and environmental benefits of paddy fields in central China.

  19. INSTITUTIONAL GLOBALIZATION AS A SYSTEM OF INTEGRATION THE PHENOMENON OF THE POSTMODERN DEVELOPMENT

    V. V. Zinchenko

    2015-12-01

    Full Text Available Purpose. Institutionalism is gaining strength as a dominant point of view on the world. Its philosophical basis is the postulate of the uncertainty of the development, which comes to replace the neoclassical certainty characteristic of industrial society. The postulate of uncertainty is closely connected with the idea of subjectivization and individualization of post-industrial society. All these were very important components of the new paradigm, although they do not exhaust the problem. In the heart of postmodernism is a mass identity as a spiritual substance, while the more recently mass of people to realize themselves as natural and social beings. Person has absolute freedom in the acceptance and rejection of culture and civilization; it is pluralistic in their actions and in their consciousness. It is the subject of history and it should be creative, fluent mastering all the achievements of culture. Methodology. The dialogue system of the Postmodern, which is the basis of human communication with another person, human with society is a model of convergent formation of the world community and world economy. The same model of rationalism and adequate industrial society is a monologue, which is easily builds a bridge to violence, even if it is carried out in the name of the man behind him and the pathos of the exaltation of man as the bearer of unlimited creation possibilities. However, it is very important not just to modify rationalism, and to understand the origins of civilization. Scientific novelty. The postmodern era begins is not easy. Modern defending, using all their reserves: public thirst for justice, the priority of rationality (at least in the economy, monologist public agencies and politicians in contrast to the dialogic postmodern imperative modality in the spiritual existence of man instead the freedom. Finally, the world of the story is set a trap – the anthropological paradigm of the globalization ideology formation. In

  20. A relationship between regional and global GCM surface air temperature changes and its application to an integrated model of climate change

    Jonas, M.; Ganopolski, A.V.; Krabec, J.; Olendrzyski, K.; Petoukhov, V.K.

    1994-01-01

    This study outlines the advantages of combining the Integrated Model to Assess the Greenhouse affect (IMAGE, an integrated quick turnaround, global model of climate change) with a spatially detailed General Circulation Model (GCM), in this case developed at the Max Planck Institute for Meteorology (MPI) in Hamburg. The outcome is a modified IMAGE model that simulates the MPI GCM projections of annual surface air temperature change globally and regionally. IMAGE thus provides policy analysts with integrated and regional information about global warming for a great range of policy-dependent greenhouse gas emission or concentration scenarios, while preserving its quick turnaround time. With the help of IMAGE various regional temperature response simulations have been produced. None of these simulations has yet been performed by any GCM. The simulations reflect the uncertainty range of a future warming. In this study the authors deal only with a simplified subsystem of such an integrated model of climate change, which begins with policy options, neglects the societal component in the greenhouse gas accounting tool, and ends with temperature change as the only output of the climate model. The model the authors employ is the Integrated Model to Assess the Greenhouse Effect (IMAGE, version 1.0), which was developed by the Netherlands National Institute of Public Health and Environmental Protection (RIVM). IMAGE is a scientifically based, parameterized simulation policy model designed to calculate the historical and future effects of greenhouse gases on global surface and surface air temperatures and sea-level rise

  1. Global Integration of the Hot-State Brain Network of Appetite Predicts Short Term Weight Loss in Older Adult

    Brielle M Paolini

    2015-05-01

    Full Text Available Obesity is a public health crisis in North America. While lifestyle interventions for weight loss (WL remain popular, the rate of success is highly variable. Clearly, self-regulation of eating behavior is a challenge and patterns of activity across the brain may be an important determinant of success. The current study prospectively examined whether integration across the Hot-State Brain Network of Appetite (HBN-A predicts WL after 6-months of treatment in older adults. Our metric for network integration was global efficiency (GE. The present work is a sub-study (n = 56 of an ongoing randomized clinical trial involving WL. Imaging involved a baseline food-cue visualization functional MRI (fMRI scan following an overnight fast. Using graph theory to build functional brain networks, we demonstrated that regions of the HBN-A (insula, anterior cingulate cortex (ACC, superior temporal pole, amygdala and the parahippocampal gyrus were highly integrated as evidenced by the results of a principal component analysis. After accounting for known correlates of WL (baseline weight, age, sex, and self-regulatory efficacy and treatment condition, which together contributed 36.9% of the variance in WL, greater GE in the HBN-A was associated with an additional 19% of the variance. The ACC of the HBN-A was the primary driver of this effect, accounting for 14.5% of the variance in WL when entered in a stepwise regression following the covariates, p = 0.0001. The HBN-A is comprised of limbic regions important in the processing of emotions and visceral sensations and the ACC is key for translating such processing into behavioral consequences. The improved integration of these regions may enhance awareness of body and emotional states leading to more successful self-regulation and to greater WL. This is the first study among older adults to prospectively demonstrate that, following an overnight fast, GE of the HBN-A during a food visualization task is predictive of

  2. Integration

    Emerek, Ruth

    2004-01-01

    Bidraget diskuterer de forskellige intergrationsopfattelse i Danmark - og hvad der kan forstås ved vellykket integration......Bidraget diskuterer de forskellige intergrationsopfattelse i Danmark - og hvad der kan forstås ved vellykket integration...

  3. Maize dependence or market integration? Caries prevalence among indigenous Maya communities with maize-based versus globalized economies.

    Vega Lizama, Elma Maria; Cucina, Andrea

    2014-02-01

    The relationship between diet and oral health is widely known, yet data on dental caries prevalence is lacking for many indigenous groups with traditional or rapidly modernizing diets. This research documents caries prevalence in two Maya communities from northern Yucatán (Mexico) with significantly different levels of market integration, subsistence, and diet: Yalsihón, with a traditional, maize-based subsistence economy, and Dzilam, with access to globalized food markets. Each sample was subdivided by sex into 15-19, 20-24, and 25-30 years-of-age classes. Caries prevalence was considered separately both when the lesion affected the enamel superficially (grade 1+) and when it reached the dentin (grade 2+). In both villages, females of all age classes manifest more caries than males. Results show higher prevalence of caries at Dzilam than at Yalsihón, except for grade 1+ caries among 15-19-year-old males and grade 2+ caries among 15-19-year-old females. Though differences are not significant, earlier pregnancies among 15-19-year-old females at Yalsihón could be a causative factor. A survey indicated a more balanced diet at Yalsihón despite a heavier intake of maize than at Dzilam. Striking differences were documented in the ingestion of soda and globalized foods; sodas were virtually absent at Yalsihón, while at Dzilam they were ingested daily in great quantities. The decline in oral health at Dzilam is inferred to result from consumption of industrially processed foods and drinks, while a traditional diet leads to less caries despite daily heavy consumption of maize, which must be considered when interpreting caries rates in archaeological samples. Copyright © 2013 Wiley Periodicals, Inc.

  4. Integrated life-cycle assessment of electricity-supply scenarios confirms global environmental benefit of low-carbon technologies.

    Hertwich, Edgar G; Gibon, Thomas; Bouman, Evert A; Arvesen, Anders; Suh, Sangwon; Heath, Garvin A; Bergesen, Joseph D; Ramirez, Andrea; Vega, Mabel I; Shi, Lei

    2015-05-19

    Decarbonization of electricity generation can support climate-change mitigation and presents an opportunity to address pollution resulting from fossil-fuel combustion. Generally, renewable technologies require higher initial investments in infrastructure than fossil-based power systems. To assess the tradeoffs of increased up-front emissions and reduced operational emissions, we present, to our knowledge, the first global, integrated life-cycle assessment (LCA) of long-term, wide-scale implementation of electricity generation from renewable sources (i.e., photovoltaic and solar thermal, wind, and hydropower) and of carbon dioxide capture and storage for fossil power generation. We compare emissions causing particulate matter exposure, freshwater ecotoxicity, freshwater eutrophication, and climate change for the climate-change-mitigation (BLUE Map) and business-as-usual (Baseline) scenarios of the International Energy Agency up to 2050. We use a vintage stock model to conduct an LCA of newly installed capacity year-by-year for each region, thus accounting for changes in the energy mix used to manufacture future power plants. Under the Baseline scenario, emissions of air and water pollutants more than double whereas the low-carbon technologies introduced in the BLUE Map scenario allow a doubling of electricity supply while stabilizing or even reducing pollution. Material requirements per unit generation for low-carbon technologies can be higher than for conventional fossil generation: 11-40 times more copper for photovoltaic systems and 6-14 times more iron for wind power plants. However, only two years of current global copper and one year of iron production will suffice to build a low-carbon energy system capable of supplying the world's electricity needs in 2050.

  5. Flash flooding: Toward an Interdisciplinary and Integrated Strategy for Disaster Reduction in a Global Environmental Change Perspective

    Ruin, Isabelle

    2014-05-01

    How do people answer to heavy precipitation and flood warnings? How do they adapt their daily schedule and activity to the fast evolution of the environmental circumstances? More generally, how do social processes interact with physical ones? Such questions address the dynamical interactions between hydro-meteorological variables, human perception and representation of the environment, and actual individual and social behavioral responses. It also poses the question of scales and hierarchy issues through seamless interactions between smaller and larger scales. These questions are relevant for both social and physical scientists. They are more and more pertinently addressed in the Global Environmental Change perspective through the concepts of Coupled Human And Natural Systems (CHANS), resilience or panarchy developped in the context of interdisciplinary collaborations. Nevertheless those concepts are complex and not easy to handle, specially when facing with operational goals. One of the main difficulty to advance these integrated approaches is the access to empirical data informing the processes at various scales. In fact, if physical and social processes are well studied by distinct disciplines, they are rarely jointly explored within similar spatial and temporal resolutions. Such coupled observation and analysis poses methodological challenges, specially when dealing with responses to short-fuse and extreme weather events. In fact, if such coupled approach is quite common to study large scale phenomenon like global change (for instance using historical data on green house gaz emissions and the evolution of temperatures worldwide), it is rarer for studing smaller nested sets of scales of human-nature systems where finer resolution data are sparse. Another problem arise from the need to produce comparable analysis on different case studies where social, physical and even cultural contexts may be diverse. Generic and robust framework for data collection, modeling

  6. ROBUST MOTION SEGMENTATION FOR HIGH DEFINITION VIDEO SEQUENCES USING A FAST MULTI-RESOLUTION MOTION ESTIMATION BASED ON SPATIO-TEMPORAL TUBES

    Brouard , Olivier; Delannay , Fabrice; Ricordel , Vincent; Barba , Dominique

    2007-01-01

    4 pages; International audience; Motion segmentation methods are effective for tracking video objects. However, objects segmentation methods based on motion need to know the global motion of the video in order to back-compensate it before computing the segmentation. In this paper, we propose a method which estimates the global motion of a High Definition (HD) video shot and then segments it using the remaining motion information. First, we develop a fast method for multi-resolution motion est...

  7. GLOFRIM v1.0 – A globally applicable computational framework for integrated hydrological–hydrodynamic modelling

    J. M. Hoch

    2017-10-01

    Full Text Available We here present GLOFRIM, a globally applicable computational framework for integrated hydrological–hydrodynamic modelling. GLOFRIM facilitates spatially explicit coupling of hydrodynamic and hydrologic models and caters for an ensemble of models to be coupled. It currently encompasses the global hydrological model PCR-GLOBWB as well as the hydrodynamic models Delft3D Flexible Mesh (DFM; solving the full shallow-water equations and allowing for spatially flexible meshing and LISFLOOD-FP (LFP; solving the local inertia equations and running on regular grids. The main advantages of the framework are its open and free access, its global applicability, its versatility, and its extensibility with other hydrological or hydrodynamic models. Before applying GLOFRIM to an actual test case, we benchmarked both DFM and LFP for a synthetic test case. Results show that for sub-critical flow conditions, discharge response to the same input signal is near-identical for both models, which agrees with previous studies. We subsequently applied the framework to the Amazon River basin to not only test the framework thoroughly, but also to perform a first-ever benchmark of flexible and regular grids on a large-scale. Both DFM and LFP produce comparable results in terms of simulated discharge with LFP exhibiting slightly higher accuracy as expressed by a Kling–Gupta efficiency of 0.82 compared to 0.76 for DFM. However, benchmarking inundation extent between DFM and LFP over the entire study area, a critical success index of 0.46 was obtained, indicating that the models disagree as often as they agree. Differences between models in both simulated discharge and inundation extent are to a large extent attributable to the gridding techniques employed. In fact, the results show that both the numerical scheme of the inundation model and the gridding technique can contribute to deviations in simulated inundation extent as we control for model forcing and boundary

  8. The OpenMI - its Transformation From a Research Output to a Global Standard for the Integrated Modelling Community

    Moore, R.

    2008-12-01

    The pressure to take a more integrated approach both to science and to management increases by the day. At almost any scale from local to global, it is no longer possible to consider issues in isolation; to do so runs a high risk of creating more problems than are solved. The consequence of this situation is that there is strong encouragement in the scientific world not just to understand and to be able to predict the response of individual processes but also to predict how those processes will interact. The manager is similarly encouraged to think in the widest terms about the likely impact of any policy before it is implemented. A new reservoir may solve a water supply problem but will it adversely affect the fishing and hence the tourist trade? How will climate change impact biodiversity? Will the drugs for treating a flu pandemic adversely affect river water quality? One approach to predicting such impacts would be to create new models simulating more and more processes. This, however, is neither feasible nor useful and makes poor use of the huge investment in existing models. A better approach, with many additional benefits, would be to find a way of linking existing models and modelling components such as databases or visualisation systems. Against this background, the European Commission, as part of its research programme to facilitate the introduction of integrated water management, commissioned a community project to find a generic solution to the linking of simulation models at run time. The outcome of this work was the Open Modelling Interface (OpenMI) standard and the creation of the OpenMI Association, an open, non-proprietary, not-for-profit, international organisation for its support. The work has received widespread recognition and encouragement from across the world, especially in the USA. A second phase is now building a community to continue the OpenMI's development and promote its use. The community's vision, mission and implementation strategy

  9. Understanding how and why health is integrated into foreign policy - a case study of health is global, a UK Government Strategy 2008–2013

    2013-01-01

    Background Over the past decade, global health issues have become more prominent in foreign policies at the national level. The process to develop state level global health strategies is arguably a form of global health diplomacy (GHD). Despite an increase in the volume of secondary research and analysis in this area, little primary research, particularly that which draws directly on the perspectives of those involved in these processes, has been conducted. This study seeks to fill this knowledge gap through an empirical case study of Health is Global: A UK Government Strategy 2008–2013. It aims to build understanding about how and why health is integrated into foreign policy and derive lessons of potential relevance to other nations interested in developing whole-of-government global health strategies. Methods The major element of the study consisted of an in-depth investigation and analysis of the UK global health strategy. Document analysis and twenty interviews were conducted. Data was organized and described using an adapted version of Walt and Gilson’s policy analysis triangle. A general inductive approach was used to identify themes in the data, which were then analysed and interpreted using Fidler’s health and foreign policy conceptualizations and Kingdon’s multiples streams model of the policymaking process. Results The primary reason that the UK decided to focus more on global health is self-interest - to protect national and international security and economic interests. Investing in global health was also seen as a way to enhance the UK’s international reputation. A focus on global health to primarily benefit other nations and improve global health per se was a prevalent through weaker theme. A well organized, credible policy community played a critical role in the process and a policy entrepreneur with expertise in both international relations and health helped catalyze attention and action on global health when the time was right. Support

  10. Globalization and regionalisation: Determinants of the transformation and the process of the integration of the geo-space

    Todorović Marina J.

    2005-01-01

    Full Text Available The two processes that, basically since the emergence of the classic civilizations, determine major changes in the basic spatial structures in the world are, de facto, of antipode basic characteristics (globalization and regionalisation, but it is often the case that there are elements with traits of complementarily. They have crucial effect on development and integration of geo-spaces and many research results indicate that, depending of the stage of the development, both processes were present in the geo-space in various forms in almost all the phases of its development and that they have contributed to establishment of all the new spatial-structural relations. The subject of this analyses is, among other issues, a brief genesis of these two processes, including identification of their main starters and effects. Besides from that, there is a special attention paid to the role of the traffic as their basic element and one of the important initiators and its role in those parts of the European continent that are not yet included by these processes of crucial changes of the geo-space as the whole.

  11. The Educated Citizen and Global Public-Health Issues: One Model for Integration into the Undergraduate Curriculum

    Caron, Rosemary M.

    2016-01-01

    The Educated Citizen Initiative proposes that an understanding of public-health issues is a core component of an educated citizenry and is essential to develop one’s societal responsibility. This initiative supports the Institute of Medicine’s recommendation that “all undergraduates should have access to education in public health.” Furthermore, the Liberal Education and America’s Promise (LEAP) framework developed by the Association of American Colleges and Universities supports the “integration of public-health education into general and liberal education with an aim to produce an educated citizenry.” The LEAP framework is implemented by teaching about the role of social determinants in a population’s health status; the significance of personal and social responsibility; and providing skills for inquiry, critical thinking, problem solving, and evaluation. This article describes one university’s experience in generating an educated citizenry cognizant of comprehensive public-health conflicts, thus contributing to both a local and global perspective on learning. PMID:26973829

  12. [Integrity].

    Gómez Rodríguez, Rafael Ángel

    2014-01-01

    To say that someone possesses integrity is to claim that that person is almost predictable about responses to specific situations, that he or she can prudentially judge and to act correctly. There is a closed interrelationship between integrity and autonomy, and the autonomy rests on the deeper moral claim of all humans to integrity of the person. Integrity has two senses of significance for medical ethic: one sense refers to the integrity of the person in the bodily, psychosocial and intellectual elements; and in the second sense, the integrity is the virtue. Another facet of integrity of the person is la integrity of values we cherish and espouse. The physician must be a person of integrity if the integrity of the patient is to be safeguarded. The autonomy has reduced the violations in the past, but the character and virtues of the physician are the ultimate safeguard of autonomy of patient. A field very important in medicine is the scientific research. It is the character of the investigator that determines the moral quality of research. The problem arises when legitimate self-interests are replaced by selfish, particularly when human subjects are involved. The final safeguard of moral quality of research is the character and conscience of the investigator. Teaching must be relevant in the scientific field, but the most effective way to teach virtue ethics is through the example of the a respected scientist.

  13. Markerless motion estimation for motion-compensated clinical brain imaging

    Kyme, Andre Z.; Se, Stephen; Meikle, Steven R.; Fulton, Roger R.

    2018-05-01

    Motion-compensated brain imaging can dramatically reduce the artifacts and quantitative degradation associated with voluntary and involuntary subject head motion during positron emission tomography (PET), single photon emission computed tomography (SPECT) and computed tomography (CT). However, motion-compensated imaging protocols are not in widespread clinical use for these modalities. A key reason for this seems to be the lack of a practical motion tracking technology that allows for smooth and reliable integration of motion-compensated imaging protocols in the clinical setting. We seek to address this problem by investigating the feasibility of a highly versatile optical motion tracking method for PET, SPECT and CT geometries. The method requires no attached markers, relying exclusively on the detection and matching of distinctive facial features. We studied the accuracy of this method in 16 volunteers in a mock imaging scenario by comparing the estimated motion with an accurate marker-based method used in applications such as image guided surgery. A range of techniques to optimize performance of the method were also studied. Our results show that the markerless motion tracking method is highly accurate (brain imaging and holds good promise for a practical implementation in clinical PET, SPECT and CT systems.

  14. Illusory motion reveals velocity matching, not foveation, drives smooth pursuit of large objects.

    Ma, Zheng; Watamaniuk, Scott N J; Heinen, Stephen J

    2017-10-01

    When small objects move in a scene, we keep them foveated with smooth pursuit eye movements. Although large objects such as people and animals are common, it is nonetheless unknown how we pursue them since they cannot be foveated. It might be that the brain calculates an object's centroid, and then centers the eyes on it during pursuit as a foveation mechanism might. Alternatively, the brain merely matches the velocity by motion integration. We test these alternatives with an illusory motion stimulus that translates at a speed different from its retinal motion. The stimulus was a Gabor array that translated at a fixed velocity, with component Gabors that drifted with motion consistent or inconsistent with the translation. Velocity matching predicts different pursuit behaviors across drift conditions, while centroid matching predicts no difference. We also tested whether pursuit can segregate and ignore irrelevant local drifts when motion and centroid information are consistent by surrounding the Gabors with solid frames. Finally, observers judged the global translational speed of the Gabors to determine whether smooth pursuit and motion perception share mechanisms. We found that consistent Gabor motion enhanced pursuit gain while inconsistent, opposite motion diminished it, drawing the eyes away from the center of the stimulus and supporting a motion-based pursuit drive. Catch-up saccades tended to counter the position offset, directing the eyes opposite to the deviation caused by the pursuit gain change. Surrounding the Gabors with visible frames canceled both the gain increase and the compensatory saccades. Perceived speed was modulated analogous to pursuit gain. The results suggest that smooth pursuit of large stimuli depends on the magnitude of integrated retinal motion information, not its retinal location, and that the position system might be unnecessary for generating smooth velocity to large pursuit targets.

  15. EDITORIAL: Siberia Integrated Regional Study: multidisciplinary investigations of the dynamic relationship between the Siberian environment and global climate change

    Gordov, E. P.; Vaganov, E. A.

    2010-03-01

    This is an editorial overview of the Siberia Integrated Regional Study (SIRS), which is a large-scale investigation of ongoing and future environmental change in Siberia and its relationship to global processes, approaches, existing challenges and future direction. Introduction The SIRS is a mega-project within the Northern Eurasia Earth Science Partnership Initiative (NEESPI), which coordinates interdisciplinary, national and international activities in Northern Eurasia that follow the Earth System Science Program (ESSP) approach. Under the direction of the International Geosphere-Biosphere Program (IGBP), SIRS is one of the Integrated Regional Studies (IRS) that aims to investigate environmental change in Siberia under the current environment of global change, and the potential impact on Earth system dynamics [1]. The regions of interest are those that may function as 'choke or switch points' for the global Earth system, where changes in regional biophysical, biogeochemical and anthropogenic components may have significant consequences for the Earth system at the global scale. Siberia is a large and significant region that may compel change [2]. Regional consequences of global warming (e.g. anomalous increases in cold season temperatures) have already been documented for Siberia [3]. This result is also supported by climate modeling results for the 20th-22nd centuries [4]. Future climatic change threatens Siberia with the shift of permafrost boundaries northward, dramatic changes in land cover (redistribution among boreal forest, wetlands, tundra, and steppe zones often precipitated by fire regime change) and the entire hydrological regime of the territory [5-8]. These processes feed back to and influence climate dynamics through the exchange of energy, water, greenhouse gases and aerosols [9]. Even though there have been a handful of national and international projects focused on the Siberian environment, scientists have minimal knowledge about the processes

  16. Media Consumption on the World Wide Web: Integrating Theories of Media Choice and Global Media Flows to Explain Global Cultural Consumption

    Taneja, Harsh

    2014-01-01

    The cross border availability of media content has raised speculations that content preferences would largely drive audience choices. In such a scenario, technologies and institutional structures would primarily shape patterns of global cultural consumption, sweeping away old allegiances based on cultural traits such as language and geography. On…

  17. Solving the Global Climate Monitoring Problem in the Atmosphere: Towards SI-tied Climate Records with Integrated Uncertainty Propagation

    Kirchengast, G.; Schwaerz, M.; Fritzer, J.; Schwarz, J.; Scherllin-Pirscher, B.; Steiner, A. K.

    2013-12-01

    Monitoring the atmosphere to gain accurate and long-term stable records of essential climate variables (ECVs) such as temperature and greenhouse gases is the backbone of contemporary atmospheric and climate science. Earth observation from space is the key to obtain such data globally in the atmosphere. Currently, however, not any existing satellite-based atmospheric ECV record can serve as authoritative benchmark over months to decades so that climate variability and change in the atmosphere are not yet reliably monitored. Radio occultation (RO) using Global Navigation Satellite System (GNSS) signals provides a unique opportunity to solve this problem in the free atmosphere (from ~1-2 km altitude upwards) for core ECVs: the thermodynamic variables temperature and pressure, and to some degree water vapor, which are key parameters for tracking climate change. On top of RO we have recently conceived next-generation methods, microwave and infrared-laser occultation and nadir-looking infrared-laser reflectometry. These can monitor a full set of thermo-dynamic ECVs (incl. wind) as well as the greenhouse gases such as carbon dioxide and methane as main drivers of climate change; for the latter we also target the boundary layer for tracking carbon sources and sinks. We briefly introduce to why the atmospheric climate monitoring challenge is unsolved so far and why just the above methods have the capabilities to break through. We then focus on RO, which already provided more than a decade of observations. RO accurately measures time delays from refraction of GNSS signals during atmospheric occultation events. This enables to tie RO-derived ECVs and their uncertainty to fundamental time standards, effectively the SI second, and to their unique long-term stability and narrow uncertainty. However, despite impressive advances since the pioneering RO mission GPS/Met in the mid-1990ties no rigorous trace from fundamental time to the ECVs (duly accounting also for relevant side

  18. Glocal clinical registries: pacemaker registry design and implementation for global and local integration--methodology and case study.

    Kátia Regina da Silva

    Full Text Available The ability to apply standard and interoperable solutions for implementing and managing medical registries as well as aggregate, reproduce, and access data sets from legacy formats and platforms to advanced standard formats and operating systems are crucial for both clinical healthcare and biomedical research settings.Our study describes a reproducible, highly scalable, standard framework for a device registry implementation addressing both local data quality components and global linking problems.We developed a device registry framework involving the following steps: (1 Data standards definition and representation of the research workflow, (2 Development of electronic case report forms using REDCap (Research Electronic Data Capture, (3 Data collection according to the clinical research workflow and, (4 Data augmentation by enriching the registry database with local electronic health records, governmental database and linked open data collections, (5 Data quality control and (6 Data dissemination through the registry Web site. Our registry adopted all applicable standardized data elements proposed by American College Cardiology / American Heart Association Clinical Data Standards, as well as variables derived from cardiac devices randomized trials and Clinical Data Interchange Standards Consortium. Local interoperability was performed between REDCap and data derived from Electronic Health Record system. The original data set was also augmented by incorporating the reimbursed values paid by the Brazilian government during a hospitalization for pacemaker implantation. By linking our registry to the open data collection repository Linked Clinical Trials (LinkedCT we found 130 clinical trials which are potentially correlated with our pacemaker registry.This study demonstrates how standard and reproducible solutions can be applied in the implementation of medical registries to constitute a re-usable framework. Such approach has the potential to

  19. Detecting PHG frames in wireless capsule endoscopy video by integrating rough global dominate-color with fine local texture features

    Liu, Xiaoqi; Wang, Chengliang; Bai, Jianying; Liao, Guobin

    2018-02-01

    Portal hypertensive gastropathy (PHG) is common in gastrointestinal (GI) diseases, and a severe stage of PHG (S-PHG) is a source of gastrointestinal active bleeding. Generally, the diagnosis of PHG is made visually during endoscopic examination; compared with traditional endoscopy, (wireless capsule endoscopy) WCE with noninvasive and painless is chosen as a prevalent tool for visual observation of PHG. However, accurate measurement of WCE images with PHG is a difficult task due to faint contrast and confusing variations in background gastric mucosal tissue for physicians. Therefore, this paper proposes a comprehensive methodology to automatically detect S-PHG images in WCE video to help physicians accurately diagnose S-PHG. Firstly, a rough dominatecolor-tone extraction approach is proposed for better describing global color distribution information of gastric mucosa. Secondly, a hybrid two-layer texture acquisition model is designed by integrating co-occurrence matrix into local binary pattern to depict complex and unique gastric mucosal microstructure local variation. Finally, features of mucosal color and microstructure texture are merged into linear support vector machine to accomplish this automatic classification task. Experiments were implemented on an annotated data set including 1,050 SPHG and 1,370 normal images collected from 36 real patients of different nationalities, ages and genders. By comparison with three traditional texture extraction methods, our method, combined with experimental results, performs best in detection of S-PHG images in WCE video: the maximum of accuracy, sensitivity and specificity reach 0.90, 0.92 and 0.92 respectively.

  20. Glocal Clinical Registries: Pacemaker Registry Design and Implementation for Global and Local Integration – Methodology and Case Study

    da Silva, Kátia Regina; Costa, Roberto; Crevelari, Elizabeth Sartori; Lacerda, Marianna Sobral; de Moraes Albertini, Caio Marcos; Filho, Martino Martinelli; Santana, José Eduardo; Vissoci, João Ricardo Nickenig; Pietrobon, Ricardo; Barros, Jacson V.

    2013-01-01

    Background The ability to apply standard and interoperable solutions for implementing and managing medical registries as well as aggregate, reproduce, and access data sets from legacy formats and platforms to advanced standard formats and operating systems are crucial for both clinical healthcare and biomedical research settings. Purpose Our study describes a reproducible, highly scalable, standard framework for a device registry implementation addressing both local data quality components and global linking problems. Methods and Results We developed a device registry framework involving the following steps: (1) Data standards definition and representation of the research workflow, (2) Development of electronic case report forms using REDCap (Research Electronic Data Capture), (3) Data collection according to the clinical research workflow and, (4) Data augmentation by enriching the registry database with local electronic health records, governmental database and linked open data collections, (5) Data quality control and (6) Data dissemination through the registry Web site. Our registry adopted all applicable standardized data elements proposed by American College Cardiology / American Heart Association Clinical Data Standards, as well as variables derived from cardiac devices randomized trials and Clinical Data Interchange Standards Consortium. Local interoperability was performed between REDCap and data derived from Electronic Health Record system. The original data set was also augmented by incorporating the reimbursed values paid by the Brazilian government during a hospitalization for pacemaker implantation. By linking our registry to the open data collection repository Linked Clinical Trials (LinkedCT) we found 130 clinical trials which are potentially correlated with our pacemaker registry. Conclusion This study demonstrates how standard and reproducible solutions can be applied in the implementation of medical registries to constitute a re-usable framework

  1. MotionFlow: Visual Abstraction and Aggregation of Sequential Patterns in Human Motion Tracking Data.

    Jang, Sujin; Elmqvist, Niklas; Ramani, Karthik

    2016-01-01

    Pattern analysis of human motions, which is useful in many research areas, requires understanding and comparison of different styles of motion patterns. However, working with human motion tracking data to support such analysis poses great challenges. In this paper, we propose MotionFlow, a visual analytics system that provides an effective overview of various motion patterns based on an interactive flow visualization. This visualization formulates a motion sequence as transitions between static poses, and aggregates these sequences into a tree diagram to construct a set of motion patterns. The system also allows the users to directly reflect the context of data and their perception of pose similarities in generating representative pose states. We provide local and global controls over the partition-based clustering process. To support the users in organizing unstructured motion data into pattern groups, we designed a set of interactions that enables searching for similar motion sequences from the data, detailed exploration of data subsets, and creating and modifying the group of motion patterns. To evaluate the usability of MotionFlow, we conducted a user study with six researchers with expertise in gesture-based interaction design. They used MotionFlow to explore and organize unstructured motion tracking data. Results show that the researchers were able to easily learn how to use MotionFlow, and the system effectively supported their pattern analysis activities, including leveraging their perception and domain knowledge.

  2. Auditory Motion Elicits a Visual Motion Aftereffect

    Christopher C. Berger

    2016-12-01

    Full Text Available The visual motion aftereffect is a visual illusion in which exposure to continuous motion in one direction leads to a subsequent illusion of visual motion in the opposite direction. Previous findings have been mixed with regard to whether this visual illusion can be induced cross-modally by auditory stimuli. Based on research on multisensory perception demonstrating the profound influence auditory perception can have on the interpretation and perceived motion of visual stimuli, we hypothesized that exposure to auditory stimuli with strong directional motion cues should induce a visual motion aftereffect. Here, we demonstrate that horizontally moving auditory stimuli induced a significant visual motion aftereffect—an effect that was driven primarily by a change in visual motion perception following exposure to leftward moving auditory stimuli. This finding is consistent with the notion that visual and auditory motion perception rely on at least partially overlapping neural substrates.

  3. Auditory Motion Elicits a Visual Motion Aftereffect.

    Berger, Christopher C; Ehrsson, H Henrik

    2016-01-01

    The visual motion aftereffect is a visual illusion in which exposure to continuous motion in one direction leads to a subsequent illusion of visual motion in the opposite direction. Previous findings have been mixed with regard to whether this visual illusion can be induced cross-modally by auditory stimuli. Based on research on multisensory perception demonstrating the profound influence auditory perception can have on the interpretation and perceived motion of visual stimuli, we hypothesized that exposure to auditory stimuli with strong directional motion cues should induce a visual motion aftereffect. Here, we demonstrate that horizontally moving auditory stimuli induced a significant visual motion aftereffect-an effect that was driven primarily by a change in visual motion perception following exposure to leftward moving auditory stimuli. This finding is consistent with the notion that visual and auditory motion perception rely on at least partially overlapping neural substrates.

  4. Auditory motion capturing ambiguous visual motion

    Arjen eAlink

    2012-01-01

    Full Text Available In this study, it is demonstrated that moving sounds have an effect on the direction in which one sees visual stimuli move. During the main experiment sounds were presented consecutively at four speaker locations inducing left- or rightwards auditory apparent motion. On the path of auditory apparent motion, visual apparent motion stimuli were presented with a high degree of directional ambiguity. The main outcome of this experiment is that our participants perceived visual apparent motion stimuli that were ambiguous (equally likely to be perceived as moving left- or rightwards more often as moving in the same direction than in the opposite direction of auditory apparent motion. During the control experiment we replicated this finding and found no effect of sound motion direction on eye movements. This indicates that auditory motion can capture our visual motion percept when visual motion direction is insufficiently determinate without affecting eye movements.

  5. Advancing Malaysia’s Aerospace Industry: A Review of Governing Behaviors Required in Overcoming the Barriers in Global Aerospace Supply Chain Integration

    Jones, David A

    2006-01-01

    The global aerospace manufacturing industry is defined by original equipment manufacturers (OEM’s) consisting of major manufacturers of aircraft or aircraft systems as well as their principal and sub-tier suppliers. It is dominated by large manufacturers known as primes supported by system integrators and numerous component, parts and material suppliers. These are focused on meeting the diverse and differing capital equipment needs of these sectors. These supply products and services in direc...

  6. Performance evaluation of latest integrated multi-satellite retrievals for Global Precipitation Measurement (IMERG) over the northern highlands of Pakistan

    Anjum, Muhammad Naveed; Ding, Yongjian; Shangguan, Donghui; Ahmad, Ijaz; Ijaz, Muhammad Wajid; Farid, Hafiz Umar; Yagoub, Yousif Elnour; Zaman, Muhammad; Adnan, Muhammad

    2018-06-01

    Recently, the Global Precipitation Measurement (GPM) mission has released the Integrated Multi-satellite Retrievals for GPM (IMERG) at a fine spatial (0.1° × 0.1°) and temporal (half hourly) resolutions. A comprehensive evaluation of this newly launched precipitation product is very important for satellite-based precipitation data users as well as for algorithm developers. The objective of this study was to provide a preliminary and timely performance evaluation of the IMERG product over the northern high lands of Pakistan. For comparison reference, the real-time and post real-time Tropical Rainfall Measuring Mission (TRMM) Multisatellite Precipitation Analysis (TMPA) products were also evaluated parallel to the IMERG. All of the selected precipitation products were evaluated at annual, monthly, seasonal and daily time scales using reference gauges data from April 2014 to December 2016. The results showed that: (1) the precipitation estimates from IMERG, 3B42V7 and 3B42RT products correlated well with the reference gauges observations at monthly time scale (CC = 0.93, 0.91, 0.88, respectively), whereas moderately at the daily time scale (CC = 0.67, 0.61, and 0.58, respectively); (2) Compared to the 3B42V7 and 3B42RT, the precipitation estimates from IMERG were more reliable in all seasons particularly in the winter season with lowest relative bias (2.61%) and highest CC (0.87); (3) IMERG showed a clear superiority over 3B42V7 and 3B42RT products in order to capture spatial distribution of precipitation over the northern Pakistan; (4) Relative to the 3B42V7 and 3B42RT, daily precipitation estimates from IMEREG showed lowest relative bias (9.20% vs. 21.40% and 26.10%, respectively) and RMSE (2.05 mm/day vs. 2.49 mm/day and 2.88 mm/day, respectively); and (5) Light precipitation events (0-1 mm/day) were usually overestimated by all said satellite-based precipitation products. In contrast moderate (1-20 mm/day) to heavy (>20 mm/day) precipitation events were

  7. Motion control report

    2013-01-01

    Please note this is a short discount publication. In today's manufacturing environment, Motion Control plays a major role in virtually every project.The Motion Control Report provides a comprehensive overview of the technology of Motion Control:* Design Considerations* Technologies* Methods to Control Motion* Examples of Motion Control in Systems* A Detailed Vendors List

  8. Global health diplomacy, national integration, and regional development through the monitoring and evaluation of HIV/AIDS programs in Papua New Guinea, Vanuatu, and Samoa.

    Kevany, Sebastian; Gildea, Amy; Garae, Caleb; Moa, Serafi; Lautusi, Avaia

    2015-04-27

    The South Pacific countries of Vanuatu, Samoa, and Papua New Guinea have ascended rapidly up the development spectrum in recent years, refining an independent and post-colonial economic and political identity that enhances their recognition on the world stage. All three countries have overcome economic, political and public health challenges in order to stake their claim to sovereignty. In this regard, the contributions of national and international programs for the diagnosis, treatment and prevention of HIV/AIDS, with specific reference to their monitoring and evaluation (M&E) aspects, have contributed not just to public health, but also to broader political and diplomatic goals such as 'nation-building'. This perspective describes the specific contributions of global health programs to the pursuit of national integration, development, and regional international relations, in Vanuatu, Samoa and Papua New Guinea, respectively, based on in-country M&E activities on behalf of the Global Fund to Fight AIDS, Tuberculosis (TB) and Malaria and the Australian Department of Foreign Affairs and Trade (DFAT) during 2014 and 2015. Key findings include: (1) that global health programs contribute to non-health goals; (2) that HIV/AIDS programs promote international relations, decentralized development, and internal unity; (3) that arguments in favour of the maintenance and augmentation of global health funding may be enhanced on this basis; and (4) that "smart" global health approaches have been successful in South Pacific countries. © 2015 by Kerman University of Medical Sciences.

  9. Re-thinking global health sector efforts for HIV and tuberculosis epidemic control: promoting integration of programme activities within a strengthened health system.

    Maher, Dermot

    2010-07-05

    The global financial crisis threatens global health, particularly exacerbating diseases of inequality, e.g. HIV/AIDS, and diseases of poverty, e.g. tuberculosis. The aim of this paper is to reconsider established practices and policies for HIV and tuberculosis epidemic control, aiming at delivering better results and value for money. This may be achieved by promoting greater integration of HIV and tuberculosis control programme activities within a strengthened health system. HIV and tuberculosis share many similarities in terms of their disease burden and the recommended stratagems for their control. HIV and tuberculosis programmes implement similar sorts of control activities, e.g. case finding and treatment, which depend for success on generic health system issues, including vital registration, drug procurement and supply, laboratory network, human resources, and financing. However, the current health system approach to HIV and tuberculosis control often involves separate specialised services. Despite some recent progress, collaboration between the programmes remains inadequate, progress in obtaining synergies has been slow, and results remain far below those needed to achieve universal access to key interventions. A fundamental re-think of the current strategic approach involves promoting integrated delivery of HIV and tuberculosis programme activities as part of strengthened general health services: epidemiological surveillance, programme monitoring and evaluation, community awareness of health-seeking behavior, risk behaviour modification, infection control, treatment scale-up (first-line treatment regimens), drug-resistance surveillance, containing and countering drug-resistance (second-line treatment regimens), research and development, global advocacy and global partnership. Health agencies should review policies and progress in HIV and tuberculosis epidemic control, learn mutual lessons for policy development and scaling up interventions, and identify ways

  10. Re-thinking global health sector efforts for HIV and tuberculosis epidemic control: promoting integration of programme activities within a strengthened health system

    Maher Dermot

    2010-07-01

    Full Text Available Abstract Background The global financial crisis threatens global health, particularly exacerbating diseases of inequality, e.g. HIV/AIDS, and diseases of poverty, e.g. tuberculosis. The aim of this paper is to reconsider established practices and policies for HIV and tuberculosis epidemic control, aiming at delivering better results and value for money. This may be achieved by promoting greater integration of HIV and tuberculosis control programme activities within a strengthened health system. Discussion HIV and tuberculosis share many similarities in terms of their disease burden and the recommended stratagems for their control. HIV and tuberculosis programmes implement similar sorts of control activities, e.g. case finding and treatment, which depend for success on generic health system issues, including vital registration, drug procurement and supply, laboratory network, human resources, and financing. However, the current health system approach to HIV and tuberculosis control often involves separate specialised services. Despite some recent progress, collaboration between the programmes remains inadequate, progress in obtaining synergies has been slow, and results remain far below those needed to achieve universal access to key interventions. A fundamental re-think of the current strategic approach involves promoting integrated delivery of HIV and tuberculosis programme activities as part of strengthened general health services: epidemiological surveillance, programme monitoring and evaluation, community awareness of health-seeking behavior, risk behaviour modification, infection control, treatment scale-up (first-line treatment regimens, drug-resistance surveillance, containing and countering drug-resistance (second-line treatment regimens, research and development, global advocacy and global partnership. Health agencies should review policies and progress in HIV and tuberculosis epidemic control, learn mutual lessons for policy

  11. Global rotation

    Rosquist, K.

    1980-01-01

    Global rotation in cosmological models is defined on an observational basis. A theorem is proved saying that, for rigid motion, the global rotation is equal to the ordinary local vorticity. The global rotation is calculated in the space-time homogeneous class III models, with Godel's model as a special case. It is shown that, with the exception of Godel's model, the rotation in these models becomes infinite for finite affine parameter values. In some directions the rotation changes sign and becomes infinite in a direction opposite to the local vorticity. The points of infinite rotation are identified as conjugate points along the null geodesics. The physical interpretation of the infinite rotation is discussed, and a comparison with the behaviour of the area distance at conjugate points is given. (author)

  12. Integral relations in complex space and the global analytic and monodromic structure of Green's functions in quantum field theory

    Bros, J.

    1980-01-01

    In this lecture, we present some of the ideas of a global consistent approach to the analytic and monodromic structure of Green's functions and scattering amplitudes of elementary particles on the basis of general quantum field theory. (orig.)

  13. Dance learning in motion: global dance education

    Brown, Ann Kipling; Koff, Susan R.; Meiners, Jeff

    2015-01-01

    Reports indicate that dance-learning experiences provided for young people in and outside schools impact positively upon young people’s learning in schools, as well as in pre-service and professional development programs for those who teach dance in various settings. Support of major dance...... organizations as well as the goals of the United Nations Educational, Scientific and Cultural Organisation (UNESCO) affirm the importance of dance education and encourage the research and practice to provide lifelong and intergenerational learning in, about and through dance education. This paper describes...... the results of a survey questionnaire, which captures the narratives and contexts from lived experiences of university students and graduates in formal, informal and non-formal settings and how those are experienced. This initial study confirmed the power of dance and the significance of dance in peoples...

  14. Albanian migration during the post communist transition and the European integration in global era - An intercultural reflection

    Agim Leka

    2013-07-01

    The religion identity of Albanian is not any essential structural component of their identity. The religion of Albanians as a part of their culture. This tendency of European society is an integrating space for Albanians. So unlike all Muslims of other countries, Albanian Muslims are integrated quickly and easily to the European secularist environment.

  15. Recent Progresses in Incorporating Human Land-Water Management into Global Land Surface Models Toward Their Integration into Earth System Models

    Pokhrel, Yadu N.; Hanasaki, Naota; Wada, Yoshihide; Kim, Hyungjun

    2016-01-01

    The global water cycle has been profoundly affected by human land-water management. As the changes in the water cycle on land can affect the functioning of a wide range of biophysical and biogeochemical processes of the Earth system, it is essential to represent human land-water management in Earth system models (ESMs). During the recent past, noteworthy progress has been made in large-scale modeling of human impacts on the water cycle but sufficient advancements have not yet been made in integrating the newly developed schemes into ESMs. This study reviews the progresses made in incorporating human factors in large-scale hydrological models and their integration into ESMs. The study focuses primarily on the recent advancements and existing challenges in incorporating human impacts in global land surface models (LSMs) as a way forward to the development of ESMs with humans as integral components, but a brief review of global hydrological models (GHMs) is also provided. The study begins with the general overview of human impacts on the water cycle. Then, the algorithms currently employed to represent irrigation, reservoir operation, and groundwater pumping are discussed. Next, methodological deficiencies in current modeling approaches and existing challenges are identified. Furthermore, light is shed on the sources of uncertainties associated with model parameterizations, grid resolution, and datasets used for forcing and validation. Finally, representing human land-water management in LSMs is highlighted as an important research direction toward developing integrated models using ESM frameworks for the holistic study of human-water interactions within the Earths system.

  16. Comparing the Global and Merged with the Local and Separate: On a Downside to the Integration of Regions and Nations

    Oded Stark

    2015-12-01

    Full Text Available This paper looks at the integration of regions and nations through the prism of the merger of populations (societies. The paper employs a particular index of social stress. Stylized examples of the merging of two populations suggest that with integration, the social stress index will increase. The examples form the basis for the development of new formulas for calculating the social stress of an integrated population as a function of the levels of social stress of the constituent populations when apart. The formulas reveal that the social stress of an integrated population is higher than the sum of the levels of social stress of the constituent populations when apart. This raises the distinct possibility that the merging of populations may be a social liability: integration may fail to give the populace a sense of improved wellbeing.

  17. 'Integration'

    Olwig, Karen Fog

    2011-01-01

    , while the countries have adopted disparate policies and ideologies, differences in the actual treatment and attitudes towards immigrants and refugees in everyday life are less clear, due to parallel integration programmes based on strong similarities in the welfare systems and in cultural notions...... of equality in the three societies. Finally, it shows that family relations play a central role in immigrants’ and refugees’ establishment of a new life in the receiving societies, even though the welfare society takes on many of the social and economic functions of the family....

  18. Globalization & technology

    Narula, Rajneesh

    Technology and globalization are interdependent processes. Globalization has a fundamental influence on the creation and diffusion of technology, which, in turn, affects the interdependence of firms and locations. This volume examines the international aspect of this interdependence at two levels...... of innovation" understanding of learning. Narula and Smith reconcile an important paradox. On the one hand, locations and firms are increasingly interdependent through supranational organisations, regional integration, strategic alliances, and the flow of investments, technologies, ideas and people...

  19. Global market integration increases likelihood that a future African Green Revolution could increase crop land use and CO2 emissions.

    Hertel, Thomas W; Ramankutty, Navin; Baldos, Uris Lantz C

    2014-09-23

    There has been a resurgence of interest in the impacts of agricultural productivity on land use and the environment. At the center of this debate is the assertion that agricultural innovation is land sparing. However, numerous case studies and global empirical studies have found little evidence of higher yields being accompanied by reduced area. We find that these studies overlook two crucial factors: estimation of a true counterfactual scenario and a tendency to adopt a regional, rather than a global, perspective. This paper introduces a general framework for analyzing the impacts of regional and global innovation on long run crop output, prices, land rents, land use, and associated CO2 emissions. In so doing, it facilitates a reconciliation of the apparently conflicting views of the impacts of agricultural productivity growth on global land use and environmental quality. Our historical analysis demonstrates that the Green Revolution in Asia, Latin America, and the Middle East was unambiguously land and emissions sparing, compared with a counterfactual world without these innovations. In contrast, we find that the environmental impacts of a prospective African Green Revolution are potentially ambiguous. We trace these divergent outcomes to relative differences between the innovating region and the rest of the world in yields, emissions efficiencies, cropland supply response, and intensification potential. Globalization of agriculture raises the potential for adverse environmental consequences. However, if sustained for several decades, an African Green Revolution will eventually become land sparing.

  20. Global market integration increases likelihood that a future African Green Revolution could increase crop land use and CO2 emissions

    Hertel, Thomas W.; Ramankutty, Navin; Baldos, Uris Lantz C.

    2014-01-01

    There has been a resurgence of interest in the impacts of agricultural productivity on land use and the environment. At the center of this debate is the assertion that agricultural innovation is land sparing. However, numerous case studies and global empirical studies have found little evidence of higher yields being accompanied by reduced area. We find that these studies overlook two crucial factors: estimation of a true counterfactual scenario and a tendency to adopt a regional, rather than a global, perspective. This paper introduces a general framework for analyzing the impacts of regional and global innovation on long run crop output, prices, land rents, land use, and associated CO2 emissions. In so doing, it facilitates a reconciliation of the apparently conflicting views of the impacts of agricultural productivity growth on global land use and environmental quality. Our historical analysis demonstrates that the Green Revolution in Asia, Latin America, and the Middle East was unambiguously land and emissions sparing, compared with a counterfactual world without these innovations. In contrast, we find that the environmental impacts of a prospective African Green Revolution are potentially ambiguous. We trace these divergent outcomes to relative differences between the innovating region and the rest of the world in yields, emissions efficiencies, cropland supply response, and intensification potential. Globalization of agriculture raises the potential for adverse environmental consequences. However, if sustained for several decades, an African Green Revolution will eventually become land sparing. PMID:25201962