WorldWideScience

Sample records for giant miniature end-plate

  1. Stationary and non-stationary occurrences of miniature end plate potentials are well described as stationary and non-stationary Poisson processes in the mollusc Navanax inermis.

    Science.gov (United States)

    Cappell, M S; Spray, D C; Bennett, M V

    1988-06-28

    Protractor muscles in the gastropod mollusc Navanax inermis exhibit typical spontaneous miniature end plate potentials with mean amplitude 1.71 +/- 1.19 (standard deviation) mV. The evoked end plate potential is quantized, with a quantum equal to the miniature end plate potential amplitude. When their rate is stationary, occurrence of miniature end plate potentials is a random, Poisson process. When non-stationary, spontaneous miniature end plate potential occurrence is a non-stationary Poisson process, a Poisson process with the mean frequency changing with time. This extends the random Poisson model for miniature end plate potentials to the frequently observed non-stationary occurrence. Reported deviations from a Poisson process can sometimes be accounted for by the non-stationary Poisson process and more complex models, such as clustered release, are not always needed.

  2. Octanol reduces end-plate channel lifetime

    Science.gov (United States)

    Gage, Peter W.; McBurney, Robert N.; Van Helden, Dirk

    1978-01-01

    1. Post-synaptic effects of n-octanol at concentrations of 0·1-1 mM were examined in toad sartorius muscles by use of extracellular and voltage-clamp techniques. 2. Octanol depressed the amplitude and duration of miniature end-plate currents and hence depressed neuromuscular transmission. 3. The decay of miniature end-plate currents remained exponential in octanol solutions even when the time constant of decay (τD) was decreased by 80-90%. 4. The lifetime of end-plate channels, obtained by analysis of acetylcholine noise, was also decreased by octanol. The average lifetime measured from noise spectra agreed reasonably well with the time constant of decay of miniature end-plate currents, both in control solution and in octanol solutions. 5. Octanol caused a reduction in the conductance of end-plate channels. Single channel conductance was on average about 25 pS in control solution and 20 pS in octanol. 6. In most cells the normal voltage sensitivity of the decay of miniature end-plate currents was retained in octanol solutions. The lifetime of end-plate channels measured from acetylcholine noise also remained voltage-sensitive in octanol solutions. In some experiments in which channel lifetime was exceptionally reduced the voltage sensitivity was less than normal. 7. In octanol solutions, τD was still very sensitive to temperature changes in most cells although in some the temperature sensitivity of τD was clearly reduced. Changes in τD with temperature could generally be fitted by the Arrhenius equation suggesting that a single step reaction controlled the decay of currents both in control and in octanol solutions. In some cells in which τD became less than 0·3 ms, the relationship between τD and temperature became inconsistent with the Arrhenius equation. 8. As the decay of end-plate currents in octanol solutions remains exponential, and the voltage and temperature sensitivity can be unchanged even when τD is significantly reduced, it seems likely that

  3. Release of fission products from miniature fuel plates at elevated temperature

    International Nuclear Information System (INIS)

    Posey, J.C.

    1982-01-01

    Three miniature fuel plates were tested at progressively higher temperatures. A U 3 Si plated blistered and released fission gases at 500 0 C. Two U 3 O 8 filled plates blistered and released fission gases at 550 0 C

  4. Release of fission products from miniature fuel plates at elevated temperature

    International Nuclear Information System (INIS)

    Posey, John C.

    1983-01-01

    Three miniature fuel plates were tested at progressively higher temperatures. A U 3 Si filled plate blistered and released fission gases at 500 deg. C. Two U 3 O 8 filled plates blistered and released fission gases at 550 deg. C. (author)

  5. Fuel cell end plate structure

    Science.gov (United States)

    Guthrie, Robin J.; Katz, Murray; Schroll, Craig R.

    1991-04-23

    The end plates (16) of a fuel cell stack (12) are formed of a thin membrane. Pressure plates (20) exert compressive load through insulation layers (22, 26) to the membrane. Electrical contact between the end plates (16) and electrodes (50, 58) is maintained without deleterious making and breaking of electrical contacts during thermal transients. The thin end plate (16) under compressive load will not distort with a temperature difference across its thickness. Pressure plate (20) experiences a low thermal transient because it is insulated from the cell. The impact on the end plate of any slight deflection created in the pressure plate by temperature difference is minimized by the resilient pressure pad, in the form of insulation, therebetween.

  6. Post-pulse detail metallographic examinations of low-enriched uranium silicide plate-type miniature fuel

    International Nuclear Information System (INIS)

    Yanagisawa, Kazuaki

    1991-10-01

    Pulse irradiation at Nuclear Safety Research Reactor (NSRR) was performed using low-enriched (19.89 w% 235 U) unirradiated silicide plate-type miniature fuel which had a density of 4.8 gU/cm 3 . Experimental aims are to understand the dimensional stability and to clarify the failure threshold of the silicide plate-type miniature fuel under power transient conditions through post-pulse detail metallographic examinations. A silicide plate-type miniature fuel was loaded into an irradiation capsule and irradiated by a single pulse. Deposited energies given in the experiments were 62, 77, 116 and 154 cal/g·fuel, which lead to corresponding peak fuel plate temperatures, 201 ± 28degC, 187 ± 10degC, 418 ± 74degC and 871 ± 74degC, respectively. Below 400degC, reliability and dimensional stability of the silicide plate fuel was sustained, and the silicide plate fuel was intact. Up to 540degC, wall-through intergranular crackings occurred in the Al-3%Mg alloy cladding. With the increase of the temperature, the melting of the aluminum cladding followed by recrystallization, the denudation of fuel core and the plate-through intergranular cracking were observed. With the increase of the temperature beyond 400degC, the bowing of fuel plate became significant. Above the temperature of 640degC molten aluminum partially reacted with the fuel core, partially flowed downward under the influence of surface tension and gravity, and partially formed agglomerations. Judging from these experimental observations, the fuel-plate above 400degC tends to reduce its dimensional stability. Despite of the apparent silicide fuel-plate failure, neither generation of pressure pulse nor that of mechanical energy occurred at all. (J.P.N.)

  7. Investigation of vertebral ''end plate sclerosis''

    International Nuclear Information System (INIS)

    Lee, S.W.; Mathie, A.G.; Jackson, J.E.; Hughes, S.P.F.

    2001-01-01

    To evaluate the association between vertebral ''end plate sclerosis'' and neck pain. A retrospective study was carried out of lateral cervical spine radiographs with a Picture Archive and Communication System (PACS). Two hundred patients' files were randomly assessed, comprising four equal groups, A to D. The mean ages of the patients were 62±7.4 years, 61±7.5 years, 40±5.6 years and 23±5.6 years respectively. In group A, all patients had symptoms of neck pain and a radiographic diagnosis of ''end plate sclerosis'' of the cervical spine. In groups B to D, asymptomatic patients were recruited and their age groups were 50-69, 30-49 and 10-29 years respectively. Using the PACS, the radiographic density and the sagittal diameter, thickness and area of the end plates at the C5 level were measured. Results and conclusions: No significant differences were found in the radiographic density of the end plates either between the symptomatic and asymptomatic groups (groups A and B), or between different age groups (groups B, C and D). A significant increase in end plate area and thickness was found, however, in both group B (P<0.005) and group C (P<0.01) in comparison with group D. This indicates that the extent of end plate sclerosis increases with age. Our results suggest that the radiographic density of cervical vertebral end plates correlates neither with neck pain nor with increasing age. The radiological sign of ''end plate sclerosis'' may be over-reported, further limiting its value in the assessment of patients with cervical spondylosis. (orig.)

  8. Compact and Light-Weight Solar Spaceflight Instrument Designs Utilizing Newly Developed Miniature Free-Standing Zone Plates: EUV Radiometer and Limb-Scanning Monochromator

    Science.gov (United States)

    Seely, J. F.; McMullin, D. R.; Bremer, J.; Chang, C.; Sakdinawat, A.; Jones, A. R.; Vest, R.

    2014-12-01

    Two solar instrument designs are presented that utilize newly developed miniature free-standing zone plates having interconnected Au opaque bars and no support membrane resulting in excellent long-term stability in space. Both instruments are based on a zone plate having 4 mm outer diameter and 1 to 2 degree field of view. The zone plate collects EUV radiation and focuses a narrow bandpass through a pinhole aperture and onto a silicon photodiode detector. As a miniature radiometer, EUV irradiance is accurately determined from the zone plate efficiency and the photodiode responsivity that are calibrated at the NIST SURF synchrotron facility. The EUV radiometer is pointed to the Sun and measures the absolute solar EUV irradiance in high time cadence suitable for solar physics and space weather applications. As a limb-scanning instrument in low earth orbit, a miniature zone-plate monochromator measures the extinction of solar EUV radiation by scattering through the upper atmosphere which is a measure of the variability of the ionosphere. Both instruments are compact and light-weight and are attractive for CubeSats and other missions where resources are extremely limited.

  9. A new miniature microchannel plate X-ray detector for synchrotron radiation

    International Nuclear Information System (INIS)

    Rosemeier, R.G.; Green, R.E. Jr.

    1982-01-01

    A state-of-the-art microchannel plate detector has been developed which allows real time X-ray imaging of X-ray diffraction as well as radiographic phenomenon. Advantages of the device include a 50 mm X-ray input, length less than 4'', and a weight of less than 1 lb. Since the use of synchrotron radiation is greatly facilitated by the capability of remote viewing of X-ray diffraction or radiographic images in real time, a prototype electro-optical system has been designed which couples the X-ray microchannel plate detector with a solid state television camera. Advantages of the miniature, lightweight, X-ray synchrotron camera include a large 50 mm X-ray input window, an output signal that is available in both analog format for display on a television monitor and in digital format for computer processing, and a completely modular design which allows all the components to be exchanged for other components optimally suited for the desired applications. (orig.)

  10. Investigation of vertebral ''end plate sclerosis''

    Energy Technology Data Exchange (ETDEWEB)

    Lee, S.W. [Dept. of Rehabilitation Sciences, Hong Kong Polytechnic Univ., Hung Hom (Hong Kong); Mathie, A.G.; Jackson, J.E. [Diagnostic Radiology, Royal Postgraduate Medical School, Hammersmith Hospital, London (United Kingdom); Hughes, S.P.F. [Div. of Surgery, Anaesthetics and Intensive Care, London (United Kingdom)

    2001-08-01

    To evaluate the association between vertebral ''end plate sclerosis'' and neck pain. A retrospective study was carried out of lateral cervical spine radiographs with a Picture Archive and Communication System (PACS). Two hundred patients' files were randomly assessed, comprising four equal groups, A to D. The mean ages of the patients were 62{+-}7.4 years, 61{+-}7.5 years, 40{+-}5.6 years and 23{+-}5.6 years respectively. In group A, all patients had symptoms of neck pain and a radiographic diagnosis of ''end plate sclerosis'' of the cervical spine. In groups B to D, asymptomatic patients were recruited and their age groups were 50-69, 30-49 and 10-29 years respectively. Using the PACS, the radiographic density and the sagittal diameter, thickness and area of the end plates at the C5 level were measured. Results and conclusions: No significant differences were found in the radiographic density of the end plates either between the symptomatic and asymptomatic groups (groups A and B), or between different age groups (groups B, C and D). A significant increase in end plate area and thickness was found, however, in both group B (P<0.005) and group C (P<0.01) in comparison with group D. This indicates that the extent of end plate sclerosis increases with age. Our results suggest that the radiographic density of cervical vertebral end plates correlates neither with neck pain nor with increasing age. The radiological sign of ''end plate sclerosis'' may be over-reported, further limiting its value in the assessment of patients with cervical spondylosis. (orig.)

  11. RF Front End Based on MEMS Components for Miniaturized Digital EVA Radio, Phase II

    Data.gov (United States)

    National Aeronautics and Space Administration — In this SBIR project, AlphaSense, Inc. and the Carnegie Mellon University propose to develop a RF receiver front end based on CMOS-MEMS components for miniaturized...

  12. Effect of nanofluids on the performance of a miniature plate heat exchanger with modulated surface

    International Nuclear Information System (INIS)

    Pantzali, M.N.; Kanaris, A.G.; Antoniadis, K.D.; Mouza, A.A.; Paras, S.V.

    2009-01-01

    In the present work, the effect of the use of a nanofluid in a miniature plate heat exchanger (PHE) with modulated surface has been studied both experimentally and numerically. First, the thermophysical properties (i.e., thermal conductivity, heat capacity, viscosity, density and surface tension) of a typical nanofluid (CuO in water, 4% v/v) were systematically measured. The effect of surface modulation on heat transfer augmentation and friction losses was then investigated by simulating the existing miniature PHE as well as a notional similar PHE with flat plate using a CFD code. Finally, the effect of the nanofluid on the PHE performance was studied and compared to that of a conventional cooling fluid (i.e., water). The results suggest that, for a given heat duty, the nanofluid volumetric flow rate required is lower than that of water causing lower pressure drop. As a result, smaller equipment and less pumping power are required. In conclusion, the use of the nanofluids seems to be a promising solution towards designing efficient heat exchanging systems, especially when the total volume of the equipment is the main issue. The only drawbacks so far are the high price and the possible instability of the nanoparticle suspensions.

  13. The effect of papaine on the time course of the end-plate current.

    Science.gov (United States)

    Humar, M; Kordas, M; Melik, Z

    1980-07-01

    Papaine is known to detach cholinesterases from the synaptic cleft. It could be expected that this would result in an increase of the amplitude and half-time of the end-plate current. Thus, the effect of papaine on the end-plate current. Thus, the effect of papaine on the end-plate current should be similar to the effect of anticholinesterase methanesulfonylfluoride. The end-plate current was recorded in frog skeletal muscle at various levels of membrane potential, before and after papaine was added to the bath. The effect of papaine was an increase of the half-time of the end-plate current, similarly as after treatment of the muscle by methanesulfonylfluoride. It seems that both papaine and methanesulfonylfluoride have a similar mechanism of action. In either experimental condition hydrolysis of transmitter is decreased or abolished, which results in an increase of the half-time of the end-plate current.

  14. Irradiation testing of miniature fuel plates for the RERTR program

    Energy Technology Data Exchange (ETDEWEB)

    Senn, R L; Martin, M M [Oak Ridge National Laboratory, Oak Ridge, TN 37830 (United States)

    1983-08-01

    An irradiation test facility, which provides a test bed for irradiating a variety of miniature fuel plates miniplates) for the Reduced Enrichment Research and Test Reactors (RERTR) program, has been placed into operation. The objective of these tests is to screen various candidate fuel materials as to their suitability for replacing the highly enriched uranium fuel materials currently used by the world's test and research reactors with a lower enrichment fuel material, without significantly degrading reactor operating characteristics and power levels. The use of low uranium enrichment of about 20% {sup 235}U in place of highly enriched fuel for these reactors would reduce the potential for {sup 235}U diversion. Fuel materials currently being evaluated in this first phase of these screening tests include aluminum-base dispersion-type fuel plates with fuel cores of 1) high uranium content U{sup 3}){sup 8}-Al being developed by ORNL, 2) high uranium content UAI{sub x}-Al being developed by EG and G Idaho, Inc., and 3) very high uranium content U{sub 3}Si-Al- being developed by ANL. The miniplates are 115-mm long by 50-mm wide with overall plate thicknesses of 1.27 or 1.52 mm. The fuel core dimensions vary according to overall plate thicknesses with a minimal clad thickness requirement of 0.20 mm. Sixty such miniplates (thirty of each thickness) can be irradiated in one test facility. The irradiation test facility, designated as HFED-1 is operating in core position E-7 in the Oak Ridge Research Reactor (ORR), a 30-MW water-moderated reactor. The peak neutron flux measured for this experiment is 1.96 x 10{sup 18} neutrons m{sub -2} s{sub -1}. The various types of miniplates will achieve burnups of up to approximately 2.2x10{sup 27} fissions/m{sup 3} of fuel, which will require approximately eight full power months of irradiation. During reactor shutdown periods, the experiment is removed from the reactor, moved to a special poolside station, disassembled, and inspected

  15. Are terrestrial plumes from motionless plates analogues to Martian plumes feeding the giant shield volcanoes?

    Science.gov (United States)

    Meyzen, Christine; Massironi, Matteo; Pozzobon, Riccardo; Dal Zilio, Luca

    2014-05-01

    The near "one-plate" planet evolution of Mars has led to the edification of long-lasting giant shied volcanoes. Unlike the Earth, Mars would have been a transient convecting planet, where plate tectonic would have possibly acted only during the first hundreds of million years of its history. On Earth, where plate tectonic is active, most of them are regenerated and recycled through convection. However, the Nubian and Antarctic plates could be considered as poorly mobile surfaces of various thicknesses that are acting as conductive lids on top of Earth's deeper convective system. In these environments, volcanoes do not show any linear age progression at least for the last 30 Ma, but constitute the sites of persistent, focused long-term magmatic activity, rather than a chain of volcanoes as observed in fast-moving plate plume environments. Here, the near stationary absolute plate motion probably exerts a primary control on volcanic processes, and more specifically, on the melting ones. The residual depleted mantle, that is left behind by the melting processes, cannot be swept away from the melting locus. Over time, the thickening of this near-stationary depleted layer progressively forces the termination of melting to higher depths, reducing the melt production rate. Such a process gradually leads both to decreasing efficient melt extraction and increasing mantle lithospheric-melt interactions. The accumulation of this refractory material also causes long-term fluctuations of the volcanic activity, in generating long periods of quiescence. The presence of this residual mantle keel induces over time a lateral flow deflection, which translates into a shift of future melting sites around it. This process gives rise to the horseshoe-like shape of some volcanic islands on slow-moving plates (e.g. Cape Verde, Crozet). Finally, the pronounced topographic swells/bulges observed in this environments may also be supported both by large scale mantle upwelling and their residual

  16. Experimental study of prequalified status of flush end plate connections

    Directory of Open Access Journals (Sweden)

    Sherif H.M. Hassanien

    2016-04-01

    Full Text Available Seismic design of steel structures is an essential part of the design process. Egyptian loading code development process continues in a high rate to catch up with emerging new concepts and standards. Steel design codes (ASD and LRFD are not developing in the same speed, which prevents the full utilization and application of loading code. The above reason leads to the need for evaluating flush end plate connections from prequalification point of view according to international standards. Due to the lack of sufficient experimental data on flush end-plate connections, an experimental program was conducted to investigate this topic. Six flush end-plate samples were designed according to the Egyptian code for steel construction (ECP205 ASD using different beam and column sections, bolt diameters and grades. A cyclic loading pattern defined by international standards was used in the testing process, and the performance was evaluated accordingly. Evaluation of M–Φ curves showed that in some cases flush end plate connections satisfy the strict requirements for prequalification. However, beam sections having limited depth fail to achieve prequalification criteria for the connections. Reduced web may be used to enhance the connection status and is investigated in one of the samples to evaluate its impact on connection performance and the failure mode. The proposed staggered hole configuration showed a promising performance.

  17. Numerical Study on Ultimate Behaviour of Bolted End-Plate Steel Connections

    Directory of Open Access Journals (Sweden)

    R.E.S. Ismail

    Full Text Available Abstract Bolted end-plate steel connections have become more popular due to ease of fabrication. This paper presents a three dimension Finite Element Model (FEM, using the multi-purpose software ABAQUS, to study the effect of different geometrical parameters on the ultimate behavior of the connection. The proposed model takes into account material and geometrical non-linearities, initial imperfection, contact between adjacent surfaces and the pretension force in the bolts. The Finite Element results are calibrated with published experimental results ''briefly reviewed in this paper'' and verified that the numerical model can simulate and analyze the overall and detailed behavior of different types of bolted end-plate steel connections. Using verified FEM, parametric study is then carried out to study the ultimate behavior with variations in: bolt diameter, end-plate thickness, length of column stiffener, angle of rib stiffener. The results are examined with respect to the failure modes, the evolution of the resistance, the initial stiffness, and the rotation capacity. Finally, the ultimate behavior of the bolted end-plate steel connection is discussed in detail, and recommendations for the design purpose are made.

  18. Comparison of the Resistance to Bending Forces of the 4.5 LCP Plate-rod Construct and of 4.5 LCP Alone Applied to Segmental Femoral Defects in Miniature Pigs

    Directory of Open Access Journals (Sweden)

    Lucie Urbanová

    2010-01-01

    Full Text Available The study deals with the determination of mechanical properties, namely resistance to bending forces, of flexible buttress osteosynthesis using two different bone-implant constructs stabilizing experimental segmental femoral bone defects (segmental ostectomy in a miniature pig ex vivo model using 4.5 mm titanium LCP and a 3 mm intramedullary pin (“plate and rod” construct (PR-LCP, versus the 4.5 mm titanium LCP alone (A-LCP. The “plate and rod” fixation (PR-LCP of the segmental femoral defect is significantly more resistant (p in vivo experiments in the miniature pig to investigate bone defect healing after transplantation of mesenchymal stem cells in combination with biocompatible scaffolds.

  19. Neuromuscular activity of Bothrops neuwiedi pauloensis snake venom in mouse nerve-muscle preparations

    Directory of Open Access Journals (Sweden)

    A. M. Durigon

    2005-03-01

    Full Text Available The pharmacological effects of Bothrops neuwiedi pauloensis venom on mouse phrenic nerve-diaphragm (PND preparations were studied. Venom (20 mug/ml irreversibly inhibited indirectly evoked twitches in PND preparations (60 ± 10% inhibition, mean ± SEM; p<0.05; n=6. At 50 mug/ml, the venom blocked indirectly and directly (curarized preparations evoked twitches in mouse hemidiaphragms. In the absence of Ca2+, venom (50 mug/ml, produced partial blockade only after an 80 min incubation, which reached 40.3 ± 7.8% (p<0.05; n=3 after 120 min. Venom (20 mug/ml increased (25 ± 2%, p< 0.05 the frequency of giant miniature end-plate potentials in 9 of 10 end-plates after 30 min and the number of miniature end-plate potentials which was maximum (562 ± 3%, p<0.05 after 120 min. During the same period, the resting membrane potential decreased from - 81 ± 1.4 mV to - 41.3 ± 3.6 mV 24 fibers; p<0.01; n=4 in the end-plate region and from - 77.4 ± 1.4 to -44.6 ± 3.9 mV (24 fibers; p<0.01; n=4 in regions distant from the end-plate. These results indicate that B. n. pauloensis venom acts primarily at presynaptic sites. They also suggest that enzymatic activity may be involved in this pharmacological action.

  20. Multiple Actions of Rotenone, an Inhibitor of Mitochondrial Respiratory Chain, on Ionic Currents and Miniature End-Plate Potential in Mouse Hippocampal (mHippoE-14 Neurons

    Directory of Open Access Journals (Sweden)

    Chin-Wei Huang

    2018-05-01

    Full Text Available Background/Aims: Rotenone (Rot is known to suppress the activity of complex I in the mitochondrial chain reaction; however, whether this compound has effects on ion currents in neurons remains largely unexplored. Methods: With the aid of patch-clamp technology and simulation modeling, the effects of Rot on membrane ion currents present in mHippoE-14 cells were investigated. Results: Addition of Rot produced an inhibitory action on the peak amplitude of INa with an IC50 value of 39.3 µM; however, neither activation nor inactivation kinetics of INa was changed during cell exposure to this compound. Addition of Rot produced little or no modifications in the steady-state inactivation curve of INa. Rot increased the amplitude of Ca2+-activated Cl- current in response to membrane depolarization with an EC50 value of 35.4 µM; further addition of niflumic acid reversed Rot-mediated stimulation of this current. Moreover, when these cells were exposed to 10 µM Rot, a specific population of ATP-sensitive K+ channels with a single-channel conductance of 18.1 pS was measured, despite its inability to alter single-channel conductance. Under current clamp condition, the frequency of miniature end-plate potentials in mHippoE-14 cells was significantly raised in the presence of Rot (10 µM with no changes in their amplitude and time course of rise and decay. In simulated model of hippocampal neurons incorporated with chemical autaptic connection, increased autaptic strength to mimic the action of Rot was noted to change the bursting pattern with emergence of subthreshold potentials. Conclusions: The Rot effects presented herein might exert a significant action on functional activities of hippocampal neurons occurring in vivo.

  1. Behavior of four-bolt extended end-plate connection subjected to lateral loading

    Directory of Open Access Journals (Sweden)

    Elsayed Mashaly

    2011-03-01

    Full Text Available A considerable number of literatures have been published on the behavior of end-plate connections in ordinary moment-resisting frames. It was found, experimentally, that this type of connection might act as either a fully-rigid or a semi-rigid connection depending mainly on the thickness of the end plate and the diameter of bolts. In recent years, due to their good ductility and their good ability of energy dissipation, extended end-plate connections are recommended to be widely used in special moment-resisting frames subjected to lateral loads. The purpose of this study is to investigate the effect of both the material and geometric properties of four-bolt extended end-plate connections upon their behavior when subjected to lateral loading. This is done through a parametric study upon a finite element model using the multi-purpose software package ANSYS. The parametric study takes into account 12 parameters which are expected to be effective on the behavior of the studied connection. The results are presented by the relation between the storey drift, which represents the rotation of the connection and the applied lateral load, which simulates the moment on the connection. The results verify that the chosen parameters are considered effective depending on the energy dissipation of the connection.

  2. Finite element analysis of an extended end-plate connection using the T-stub approach

    Energy Technology Data Exchange (ETDEWEB)

    Muresan, Ioana Cristina; Balc, Roxana [Technical University of Cluj-Napoca, Faculty of Civil Engineering. 15 C Daicoviciu Str., 400020, Cluj-Napoca (Romania)

    2015-03-10

    Beam-to-column end-plate bolted connections are usually used as moment-resistant connections in steel framed structures. For this joint type, the deformability is governed by the deformation capacity of the column flange and end-plate under tension and elongation of the bolts. All these elements around the beam tension flange form the tension region of the joint, which can be modeled by means of equivalent T-stubs. In this paper a beam-to-column end-plate bolted connection is substituted with a T-stub of appropriate effective length and it is analyzed using the commercially available finite element software ABAQUS. The performance of the model is validated by comparing the behavior of the T-stub from the numerical simulation with the behavior of the connection as a whole. The moment-rotation curve of the T-stub obtained from the numerical simulation is compared with the behavior of the whole extended end-plate connection, obtained by numerical simulation, experimental tests and analytical approach.

  3. Giant cells tumor of radius distal end and bone reconstruction

    International Nuclear Information System (INIS)

    La O Duran, Eldis; Monzon Fernandez, Abel Nicolas; Sanz Delgado, Licett

    2009-01-01

    This is the case of a black women aged 40 presenting with a tumor of distal end of right radium with histological diagnosis of low-grade malignancy giant cells tumor and proposal of limb amputation. A conservative surgery was performed with a two-steps total exeresis of lesion sparing the oncologic margin. A fibular free-graft was used and wrist arthrodesis and internal fixation of graft using AO system. There was a good graft consolidation and an active incorporation of patient to social activities. The diagnosis, treatment, follow-up, rehabilitation and case prognosis are exposed

  4. End plate marrow changes in the asymptomatic lumbosacral spine: frequency, distribution and correlation with age and degenerative changes

    International Nuclear Information System (INIS)

    Chung, Christine B.; Vande Berg, Bruno C.; Malghem, Jacques; Tavernier, Thierry; Cotten, Anne; Laredo, Jean-Denis; Vallee, Christian

    2004-01-01

    To investigate the frequency and distribution of end plate marrow signal intensity changes in an asymptomatic population and to correlate these findings with patient age and degenerative findings in the spine. MR imaging studies of the lumbosacral (LS) spine in 59 asymptomatic subjects were retrospectively reviewed by 2 musculoskeletal radiologists to determine the presence and location of fat-like and edema-like marrow signal changes about the end plates of the L1-2 through L5-S1 levels. The presence of degenerative changes in the spine was recorded as was patient age. Descriptive statistics were utilized to determine the frequency and associations of end plate findings and degenerative changes in the spine. Interobserver variability was determined by a kappa score. Binomial probability was used to predict the prevalence of the end plate changes in a similar subject population. The Fisher exact test was performed to determine statistical significance of the relationship of end plate changes with degenerative changes in the spine, superior versus inferior location about the disc and age of the patient population. Focal fat-like signal intensity adjacent to the vertebral end-plate was noted in 15 out of 59 subjects by both readers, and involved 38 and 36 out of 590 end plates by readers 1 and 2, respectively. Focal edema-like signal intensity adjacent to the vertebral end plate was noted in 8 out of 59 subjects by both readers and involved 11 and 10 out of 590 end plates by readers 1 and 2, respectively. Either fat or edema signal intensity occurred most often at the anterior (p<.05) aspects of the mid-lumbar spine and was seen in an older sub-population of the study (p<.05). End plate marrow signal intensity changes are present in the lumbar spine of some asymptomatic subjects with a characteristic location along the spine and in vertebral end plates. (orig.)

  5. Miniaturization in Biocatalysis

    Directory of Open Access Journals (Sweden)

    Pedro Fernandes

    2010-03-01

    Full Text Available The use of biocatalysts for the production of both consumer goods and building blocks for chemical synthesis is consistently gaining relevance. A significant contribution for recent advances towards further implementation of enzymes and whole cells is related to the developments in miniature reactor technology and insights into flow behavior. Due to the high level of parallelization and reduced requirements of chemicals, intensive screening of biocatalysts and process variables has become more feasible and reproducibility of the bioconversion processes has been substantially improved. The present work aims to provide an overview of the applications of miniaturized reactors in bioconversion processes, considering multi-well plates and microfluidic devices, update information on the engineering characterization of the hardware used, and present perspective developments in this area of research.

  6. Effects of the partially movable control fin with end plate of underwater vehicle

    Directory of Open Access Journals (Sweden)

    Chul-Min Jung

    2017-01-01

    Full Text Available Underwater torpedo has control fin with very low aspect ratio due to launching from limited size of cylindrical torpedo tube. If the aspect ratio of control fin of underwater vehicle is very low three-dimensional flow around control fin largely reduces control forces. In this study, the end plate was applied to reduce the three-dimensional flow effects of partially movable control fin of underwater vehicle. Through numerical simulations the flow field around control fin was examined with and without end plate for different flap angles. The pressure, vorticity, lift and torque on the control fin were analyzed and compared to experiments. The comparison have shown a reasonable agreement between numerical and experimental results and the effect of end plate on a low aspect ratio control fin. When the end plate was attached to the movable control fin, the lift increased and the actuator shaft torque did not significantly change. As this means less consumption of the actuator shaft torque compared to the control fin that has the same control force, the inner actuator capacity can be reduced and energy consumption can be saved. Considering this, it is expected to be effectively applied to the control fin design of underwater vehicles such as torpedoes.

  7. Analysis of the Behaviour of Semi Rigid Steel End Plate Connections

    Directory of Open Access Journals (Sweden)

    Bahaz A.

    2018-01-01

    Full Text Available The analysis of steel-framed building structures with full strength beam to column joints is quite standard nowadays. Buildings utilizing such framing systems are widely used in design practice. However, there is a growing recognition of significant benefits in designing joints as partial strength/semi-rigid. The design of joints within this partial strength/semi-rigid approach is becoming more and more popular. This requires the knowledge of the full nonlinear moment-rotation behaviour of the joint, which is also a design parameter. The rotational behaviour of steel semi rigid connections can be studied using the finite element method for the following three reasons: i such models are inexpensive; ii they allow the understanding of local effects, which are difficult to measure accurately physically, and iii they can be used to generate extensive parametric studies. This paper presents a three-dimensional finite element model using ABAQUS software in order to identify the effect of different parameters on the behaviour of semi rigid steel beam to column end plate connections. Contact and sliding between different elements, bolt pretension and geometric and material non-linearity are included in this model. A parametric study is conducted using a model of two end-plate configurations: flush and extended end plates. The studied parameters were as follows: bolts type, end plate thickness and column web stiffener. Then, the model was calibrated and validated with experimental results taken from the literature and with the model proposed by Eurocode3. The procedure for determining the moment–rotation curve using finite element analysis is also given together with a brief explanation of how the design moment resistance and the initial rotational stiffness of the joint are obtained.

  8. Morphologic and radiologic data of isolated vertebral end-plates under particular consideration of radiodensitometry

    International Nuclear Information System (INIS)

    Unflath, U.

    1979-01-01

    The intention was to find examination techniques for macroscopico-morphological diagnosis, for quantification of the concavity and methods for roentgenologico-densitometric analysis of vertebral end-plates. The following factors were used for macromorphologic diagnosis: osteophytes, ridge constitution, ridge transition, cribriform plate and concavity. The radiodensitometric analysis comprised investigation of bone density, anisotropy and ridge mineralisation. The specimen were radiographed on a mammograph together with calcium chloride solutions of increasing concentration. Statistically significant differences in the behaviour of basal and upper plates were not observed. With reference to the factors osteophytes and ridge constitution the basal plates seem to be morphologically more variable than the upper plates. It resulted that the features absolute concavity and concavity quotient are highly appropriate factors to document the constitution of the isolated vertebral end-plates. Also the features density, anisotropy and ridge mineralisation were found to be useful for documentation. The result of data correlation was that high concavity quotients are accompanied by macroscopically medium- to small-sized pores. Density and anisotropy of the overall profiles do not show correlation, but voluminous cribriform laminae tend to develop more inhomogenic structures. As to be expected, bone density increases with macroscopic fine porosity. The higher the concavity quotient is, the smaller are the values for density, ridge mineralisation and anisotropy. Thus a high degree of vertebral end-plate concavity indicates reduced bone density and lower mineral content. (orig./MG) [de

  9. Giant graviton interactions and M2-branes ending on multiple M5-branes

    Science.gov (United States)

    Hirano, Shinji; Sato, Yuki

    2018-05-01

    We study splitting and joining interactions of giant gravitons with angular momenta N 1/2 ≪ J ≪ N in the type IIB string theory on AdS 5 × S 5 by describing them as instantons in the tiny graviton matrix model introduced by Sheikh-Jabbari. At large J the instanton equation can be mapped to the four-dimensional Laplace equation and the Coulomb potential for m point charges in an n-sheeted Riemann space corresponds to the m-to- n interaction process of giant gravitons. These instantons provide the holographic dual of correlators of all semi-heavy operators and the instanton amplitudes exactly agree with the pp-wave limit of Schur polynomial correlators in N = 4 SYM computed by Corley, Jevicki and Ramgoolam. By making a slight change of variables the same instanton equation is mathematically transformed into the Basu-Harvey equation which describes the system of M2-branes ending on M5-branes. As it turns out, the solutions to the sourceless Laplace equation on an n-sheeted Riemann space correspond to n M5-branes connected by M2-branes and we find general solutions representing M2-branes ending on multiple M5-branes. Among other solutions, the n = 3 case describes an M2-branes junction ending on three M5-branes. The effective theory on the moduli space of our solutions might shed light on the low energy effective theory of multiple M5-branes.

  10. Improving the performances of H-Darrieus cross-flow turbines through proper detached end plate designs

    Science.gov (United States)

    Villeneuve, Thierry; Boudreau, Matthieu; Dumas, Guy; CFD Laboratory LMFN Team

    2017-11-01

    Previous studies on H-Darrieus cross-flow turbines have highlighted the fact that their performances are highly sensitive to the detrimental effects associated with the blades tips. Wingtip devices could be designed in order to attenuate these effects, but the benefits of such devices are always impaired by their added viscous drag since they are moving with the turbine's blades. In this context, the development of fixed and detached end plates, i.e., which are not in contact with the turbine's blades, could reduce the tip losses without the undesirable added drag of typical wingtip devices moving with the blades. The case of a single stationary blade with detached end plates has first been investigated with RANS simulations in order to understand the mechanisms responsible for the increase of the blade's lift. An analysis of the vorticity lines' dynamics provides crucial insights into the effects of the gap width between the blade and the detached end plate on the blade's loading and on the intensity of the tip vortices. Based on these observations, various configurations of detached end plates are tested on cross-flow turbines via RANS and DDES simulations. Preliminary results show that appropriate detached end plates can significantly increase the turbines' efficiency. The authors gratefully acknowledge the Natural Sciences and Engineering Research Council of Canada (NSERC) for their financial support as well as Compute Canada and Calcul Québec for their supercomputer allocations.

  11. Open reduction and cranial bone plate fixation of fractures involving the distal aspect of the radius and ulna in miniature- and toy-breed dogs: 102 cases (2008-2015).

    Science.gov (United States)

    De Arburn Parent, Rebecca; Benamou, Jérôme; Gatineau, Matthieu; Clerfond, Pierre; Planté, Jérôme

    2017-06-15

    OBJECTIVE To determine outcomes and complication rates of open reduction and cranial bone plate fixation of fractures involving the distal aspect of the radius and ulna in miniature- and toy-breed dogs. DESIGN Retrospective case series. ANIMALS 102 miniature- and toy-breed dogs (105 fractures) weighing ≤ 7 kg (15.4 lb) that had undergone open reduction and cranial bone plate fixation of a fracture involving the distal aspect of the radius and ulna from 2008 through 2015. PROCEDURES Medical records were reviewed and information extracted regarding dog and fracture characteristics, surgical variables, and follow-up examination data (including postoperative complications). Postoperative radiographs were examined for distal fragment size, implant placement, apposition, alignment, and healing stage. A long-term follow-up questionnaire was completed by telephone interview with dog owners at least 6 months after surgery. RESULTS Mean length of the distal bone fragment in all fractures was 19.2 mm, with a mean distal-to-total radial length ratio of 0.21. At last follow-up examination (typically 6 weeks after surgery), 97 (95%) dogs had no signs of lameness; minor lameness was identified in 5 (5%) dogs. Complications developed in 26 (25%) fractures (23 [22%] minor and 3 [3%] major complications). Sixty-eight of 71 (96%) owners rated the overall and long-term outcome as excellent and 3 (4%) as good; 68 of 71 (96%) dogs reportedly had no signs of residual lameness. CONCLUSIONS AND CLINICAL RELEVANCE Open reduction and cranial bone plate fixation for the treatment of radius-ulna fractures in miniature- and toy-breed dogs provided an excellent outcome with a low complication rate.

  12. End plate for e.g. solid oxide fuel cell stack, sets thermal expansion coefficient of material to predetermined value

    DEFF Research Database (Denmark)

    2011-01-01

    .05-0.3 mm. USE - End plate for solid oxide fuel cell stack (claimed). Can also be used in polymer electrolyte fuel cell stack and direct methanol fuel cell stack. ADVANTAGE - The robustness of the end plate is improved. The structure of the end plate is simplified. The risk of delamination of the stack...

  13. Miniaturized Optical Tweezers Through Fiber-End Microfabrication

    KAUST Repository

    Liberale, Carlo; Cojoc, Gheorghe; Rajamanickam, Vijayakumar; Ferrara, Lorenzo; Bragheri, Francesca; Minzioni, Paolo; Perozziello, Gerardo; Candeloro, Patrizio; Cristiani, Ilaria; Di Fabrizio, Enzo M.

    2014-01-01

    Optical tweezers represent a powerful tool for a variety of applications both in biology and in physics, and their miniaturization and full integration is of great interest so as to reduce size (towards portable systems), and to minimize the required intervention from the operator. Optical fibers represent a natural solution to achieve this goal, and here we review the realization of single-fiber optical tweezers able to create a purely optical three-dimensional trap. © Springer International Publishing Switzerland 2015.

  14. Miniaturized Optical Tweezers Through Fiber-End Microfabrication

    KAUST Repository

    Liberale, Carlo

    2014-07-30

    Optical tweezers represent a powerful tool for a variety of applications both in biology and in physics, and their miniaturization and full integration is of great interest so as to reduce size (towards portable systems), and to minimize the required intervention from the operator. Optical fibers represent a natural solution to achieve this goal, and here we review the realization of single-fiber optical tweezers able to create a purely optical three-dimensional trap. © Springer International Publishing Switzerland 2015.

  15. A global limit load solution for plates with surface cracks under combined end force and cross-thickness bending

    International Nuclear Information System (INIS)

    Lei Yuebao; Fox, Mike J.H.

    2011-01-01

    A global limit load solution for rectangular surface cracks in plates under combined end force and cross-thickness bending is derived, which allows any combination of positive/negative end force and positive/negative cross-thickness moment. The solution is based on the net-section plastic collapse concept and, therefore, gives limit load values based on the Tresca yielding criterion. Solutions for both cases with and without crack face contact are derived when whole or part of the crack is located in the compressive stress zone. From the solution, particular global limit load solutions for plates with extended surface cracks and through-thickness cracks under the same loading conditions are obtained. The solution is consistent with the limit load solution for surface cracks in plates under combined tension and positive bending due to Goodall and Webster and Lei when both the applied end force and bending moment are positive. The solution reduces to the limit load solution for plain plates under combined end force and cross-thickness bending when the crack vanishes. - Highlights: → A global limit load solution for plates with surface cracks in plates is derived. → Combined positive/negative end force and positive/negative cross-thickness moment are considered. → The solution is based on the net-section plastic collapse concept.

  16. End plates made of a composite material for the revolving drum of a centrifuge

    International Nuclear Information System (INIS)

    Yamanaka, T.; Onishi, H.; Fujiwara, M.

    1980-01-01

    The present invention relates to improvement of the end plates of centrifuges, especially those for centrifugal gas separators. End plates made of a composite material for the revolving drum of a centrifuge consists of a carbon-fiber-reinforced plastic layer. This layer consists of carbon fibers either wound helically at an angle greater than 75 0 and less than 90 0 to the center line of revolution, or wound in a hoop, and a matrix of a thermosetting resin in which the carbon fibers are buried, which [matrix] is laminated with metal layers

  17. Some aspects of thick, soft nickel plating for end shields of atomic power plants

    International Nuclear Information System (INIS)

    Krishnaswamy, R.

    1987-01-01

    Thick (55 Thou) and soft (160 vickers) hardness number nickel plating over SS for RAPP end shields presented unusual problems as the thickness required was extremely large creating adhesion problems and the extremely stringent hardness conditions. A sulfamate bath with nickel anode was found suitable. The problems in thick, soft plating, the chemical and other procedures adopted to monitor the bath and the plated specimen and the other details are presented. (author). 11 refs

  18. A Miniaturized Force Sensor Based on Hair-Like Flexible Magnetized Cylinders Deposited Over a Giant Magnetoresistive Sensor

    KAUST Repository

    Ribeiro, Pedro

    2017-06-13

    The detection of force with higher resolution than observed in humans (similar to 1 mN) is of great interest for emerging technologies, especially surgical robots, since this level of resolution could allow these devices to operate in extremely sensitive environments without harming these. In this paper, we present a force sensor fabricated with a miniaturized footprint (9 mm(2)), based on the detection of the magnetic field generated by magnetized flexible pillars over a giant magnetoresistive sensor. When these flexible pillars deflect due to external loads, the stray field emitted by these will change, thus varying the GMR sensor resistance. A sensor with an array of five pillars with 200 mu m diameter and 1 mm height was fabricated, achieving a 0 to 26 mN measurement range and capable of detecting a minimum force feature of 630 mu N. A simulation model to predict the distribution of magnetic field generated by the flexible pillars on the sensitive area of the GMR sensor in function of the applied force was developed and validated against the experimental results reported in this paper. The sensor was finally tested as a texture classification system, with the ability of differentiating between four distinct surfaces varying between 0 and 162 mu m root mean square surface roughness.

  19. A Miniaturized Force Sensor Based on Hair-Like Flexible Magnetized Cylinders Deposited Over a Giant Magnetoresistive Sensor

    KAUST Repository

    Ribeiro, Pedro; Khan, Mohammed Asadullah; Alfadhel, Ahmed; Kosel, Jü rgen; Franco, Fernando; Cardoso, Susana; Bernardino, Alexandre; Santos-Victor, Jose; Jamone, Lorenzo

    2017-01-01

    The detection of force with higher resolution than observed in humans (similar to 1 mN) is of great interest for emerging technologies, especially surgical robots, since this level of resolution could allow these devices to operate in extremely sensitive environments without harming these. In this paper, we present a force sensor fabricated with a miniaturized footprint (9 mm(2)), based on the detection of the magnetic field generated by magnetized flexible pillars over a giant magnetoresistive sensor. When these flexible pillars deflect due to external loads, the stray field emitted by these will change, thus varying the GMR sensor resistance. A sensor with an array of five pillars with 200 mu m diameter and 1 mm height was fabricated, achieving a 0 to 26 mN measurement range and capable of detecting a minimum force feature of 630 mu N. A simulation model to predict the distribution of magnetic field generated by the flexible pillars on the sensitive area of the GMR sensor in function of the applied force was developed and validated against the experimental results reported in this paper. The sensor was finally tested as a texture classification system, with the ability of differentiating between four distinct surfaces varying between 0 and 162 mu m root mean square surface roughness.

  20. Connection between end plates and rods in a BWR fuel element

    International Nuclear Information System (INIS)

    Cali', G.P.

    1975-01-01

    The problem of the connection between the end plates and the rods of a BWR fuel element is analytically formulated. The behaviour of the springs coupling the rods with the upper plate is analyzed with particular detail since the deformation of these springs affects the forces at the interface of the fuel element structure components. A tool is given to design the springs according to some considerations regarding the mechanical strength of the interacting components as well as the influence of the possible geometrical unevennes of the system that can arise during the fuel element lifetime. (Cali', G.P.)

  1. A study of open strings ending on giant gravitons, spin chains and integrability

    International Nuclear Information System (INIS)

    Berenstein, David; Correa, Diego H.; Vazquez, Samuel E.

    2006-01-01

    We systematically study the spectrum of open strings attached to half BPS giant gravitons in the N = 4 SYM AdS/CFT setup. We find that some null trajectories along the giant graviton are actually null geodesics of AdS 5 x S 5 , so that we can study the problem in a plane wave limit setup. We also find the description of these states at weak 't Hooft coupling in the dual CFT. We show how the dual description is given by an open spin chain with variable number of sites. We analyze this system in detail and find numerical evidence for integrability. We also discover an interesting instability of long open strings in Ramond-Ramond backgrounds that is characterized by having a continuum spectrum of the string, which is separated from the ground state by a gap. This instability arises from accelerating the D-brane on which the strings end via the Ramond-Ramond field. From the integrable spin chain point of view, this instability prevents us from formulating the integrable structure in terms of a Bethe Ansatz construction

  2. Longitudinal study of vertebral type-1 end-plate changes on MR of the lumbar spine

    Energy Technology Data Exchange (ETDEWEB)

    Mitra, D. [Department of Neuroradiology, Newcastle General Hospital, Westgate Road, NE4 6BE, Newcastle upon Tyne (United Kingdom); Cassar-Pullicino, V.N.; Mccall, I.W. [Department of Radiology, Robert Jones and Agnes Hunt Orthopaedic Hospital, Oswestry (United Kingdom)

    2004-09-01

    The purpose of this study was to investigate the temporal evolution of type-1 end-plate changes on MRI in patients with degenerative disease of the lumbar spine and to evaluate whether any correlation exists between such evolution and the change in patients' symptoms. Forty-four patients with 48 Modic type-1 end-plate changes (low TI signal and high T2 signal) were studied. All patients had an initial and a follow-up non-contrast lumbar MRI with variable intervals between the studies (12-72 months). Severity of the end-plate changes was assessed by eyeball estimation. Correlation with patients' symptoms was studied with the help of the Visual Analogue Score (VAS), Oswestry Questionnaire Score (OQS) and patients' subjective assessment. Of the 48 disc levels with type-1 changes, 18 (37.5%) converted fully to type 2 (high T1 signal and intermediate to high T2 signal), 7 (14.6%) partially converted to type 2, 19 (39.6%) became worse (i.e. type 1 changes became more extensive) and 4 (8.3%) showed no change. Higher average VAS (5.7) and OQS (42.3) scores were noted in patients where there was worsening type-1 change and lower scores (3.8 and 27, respectively) were seen in those where there was conversion to type-2 change. These trends, however, did not reach statistical significance (P values 0.16 and 0.09 for VAS and OQS, respectively). The statistical relationship was stronger after exclusion of patients with confounding factors (i.e. changes in lumbar MRI other than end-plate changes that could independently explain the evolution of patients' symptoms) with P-values of 0.08 and 0.07 for VAS and OQS, respectively. Type-1 end-plate change represents a dynamic process and in a large majority of cases either converts to type-2 change or becomes more extensive. The evolution of type-1 change relates to change in patient's symptoms, but not to a statistically significant level. (orig.)

  3. Longitudinal study of vertebral type-1 end-plate changes on MR of the lumbar spine

    International Nuclear Information System (INIS)

    Mitra, D.; Cassar-Pullicino, V.N.; Mccall, I.W.

    2004-01-01

    The purpose of this study was to investigate the temporal evolution of type-1 end-plate changes on MRI in patients with degenerative disease of the lumbar spine and to evaluate whether any correlation exists between such evolution and the change in patients' symptoms. Forty-four patients with 48 Modic type-1 end-plate changes (low TI signal and high T2 signal) were studied. All patients had an initial and a follow-up non-contrast lumbar MRI with variable intervals between the studies (12-72 months). Severity of the end-plate changes was assessed by eyeball estimation. Correlation with patients' symptoms was studied with the help of the Visual Analogue Score (VAS), Oswestry Questionnaire Score (OQS) and patients' subjective assessment. Of the 48 disc levels with type-1 changes, 18 (37.5%) converted fully to type 2 (high T1 signal and intermediate to high T2 signal), 7 (14.6%) partially converted to type 2, 19 (39.6%) became worse (i.e. type 1 changes became more extensive) and 4 (8.3%) showed no change. Higher average VAS (5.7) and OQS (42.3) scores were noted in patients where there was worsening type-1 change and lower scores (3.8 and 27, respectively) were seen in those where there was conversion to type-2 change. These trends, however, did not reach statistical significance (P values 0.16 and 0.09 for VAS and OQS, respectively). The statistical relationship was stronger after exclusion of patients with confounding factors (i.e. changes in lumbar MRI other than end-plate changes that could independently explain the evolution of patients' symptoms) with P-values of 0.08 and 0.07 for VAS and OQS, respectively. Type-1 end-plate change represents a dynamic process and in a large majority of cases either converts to type-2 change or becomes more extensive. The evolution of type-1 change relates to change in patient's symptoms, but not to a statistically significant level. (orig.)

  4. Fracture Characteristics Analysis of Double-layer Rock Plates with Both Ends Fixed Condition

    Directory of Open Access Journals (Sweden)

    S. R. Wang

    2014-07-01

    Full Text Available In order to research on the fracture and instability characteristics of double-layer rock plates with both ends fixed, the three-dimension computational model of double-layer rock plates under the concentrated load was built by using PFC3D technique (three-dimension particle flow code, and the mechanical parameters of the numerical model were determined based on the physical model tests. The results showed the instability process of the double-layer rock plates had four mechanical response phases: the elastic deformation stage, the brittle fracture of upper thick plate arching stage, two rock-arch bearing stage and two rock-arch failure stage; moreover, with the rock plate particle radius from small to large change, the maximum vertical force of double rock-arch appeared when the particle size was a certain value. The maximum vertical force showed an upward trend with the increase of the rock plate temperature, and in the case of the same thickness the maximum vertical force increased with the increase of the upper rock plate thickness. When the boundary conditions of double-layer rock plates changed from the hinged support to the fixed support, the maximum horizontal force observably decreased, and the maximum vertical force showed small fluctuations and then tended towards stability with the increase of cohesive strength of double-layer rock plates.

  5. Magnetic giant magnetoresistance commercial off the shelf for space applications

    DEFF Research Database (Denmark)

    Michelena, M.D.; Oelschlägel, Wulf; Arruego, I.

    2008-01-01

    The increase of complexity and miniaturizing level of Aerospace platforms make use of commercial off the shelf (COTS) components constitute a plausible alternative to the use of military or rad-tolerant components. In this work, giant magnetoresistance commercial sensors are studied to be used as......-375 mu T biasing field. (c) 2008 American Institute of Physics....

  6. Experimental Research on Seismic Performance of a New-Type of R/C Beam-Column Joints with End Plates

    Directory of Open Access Journals (Sweden)

    Shufeng Li

    2017-01-01

    Full Text Available This paper presents a new-type of fabricated beam-column connections with end plates. The joint details are as follows: the concrete beams are connected to column by end plates and six high strength long bolts passing through the core area. In addition, in order to increase the stiffness and shear strength, stirrups are replaced by the steel plate hoop in the core zone. To examine the fail behavior of the fabricated beam-column connection specimens, a quasi-static test is conducted for nine full-scale models to obtain the hysteresis curves, skeleton curves, ductility, energy dissipation capacity, and other seismic indicators. The experimental results show that all specimens failed in bending in a malleable way with a beam plastic hinge and the hysteresis curves are excellently plump for the end plate connections. From the seismic indexes, the fabricated connection specimens exhibit better seismic performance, which can provide reference for the application of prefabricated frame structure in the earthquake area.

  7. Probing the Deep End of the Milky Way with New Oscillating Kepler Giants

    Science.gov (United States)

    Mathur, Savita; García, Rafael A.; Huber, Daniel; Regulo, Clara; Stello, Dennis; Beck, Paul G.; Houmani, Kenza; Salabert, David

    2017-10-01

    The Kepler mission has been a success in both exoplanet search and stellar physics studies. Red giants have actually been quite a highlight in the Kepler scene. The Kepler long and almost continuous four-year observations allowed us to detect oscillations in more than 15,000 red giants targeted by the mission. However by looking at the power spectra of 45,000 stars classified as dwarfs according to the Q1-16 Kepler star properties catalog, we detected red-giant like oscillations in 850 stars. Even though this is a small addition to the known red-giant sample, these misclassified stars represent a goldmine for galactic archeology studies. Indeed they happen to be fainter (down to Kp 16) and more distant (d>10kPc) than the known red giants, opening the possibility to probe unknown regions of our Galaxy. The faintness of these red giants with detected oscillations is very promising for detecting acoustic modes in red giants observed with K2 and TESS. In this talk, I will present this new sample of red giants with their revised stellar parameters derived from asteroseismology. Then I will discuss about the distribution of their masses, distances, and evolutionary states compared to the previously known sample of red giants.

  8. Case report 353: Giant cell tumor of distal end of the femur, containing a fluid level as demonstrated by computed tomography

    International Nuclear Information System (INIS)

    Resnik, C.S.; Steffe, J.W.; Wang, S.E.

    1986-01-01

    In summary, a 22-year-old man presented after sustaining a minor injury to his left knee while playing football. Radiological studies showed the characteristic stigmata of a giant cell tumor in the distal end of the femur involving the medial femoral condyle. On computed tomography with the proper window settings a fluid level was demonstrated in the osteolytic lesion. At surgery, yellowish sanguinous fluid was aspirated from the lesion which was completely curetted. Pathological studies showed the typical stigmata of a giant cell tumor. (orig./SHA)

  9. Local heat transfer performance and exit flow characteristics of a miniature axial fan

    International Nuclear Information System (INIS)

    Stafford, Jason; Walsh, Ed; Egan, Vanessa

    2010-01-01

    Dimensional restrictions in electronic equipment have resulted in miniaturization of many existing cooling technologies. In addition to this, cooling solutions are required to dissipate increased thermal loads to maintain component reliability. Axial fans are widely used in electronics cooling to meet such thermal demands. However, if the extent of non-uniform heat transfer rates, produced by highly three-dimensional air patterns is unknown in the design stages, premature component failure may result. The current study highlights these non-uniformities in heat transfer coefficient, using infrared thermography of a miniature axial fan impinging air on a flat plate. Fan rotational speed and distance from the flat plate are varied to encompass heat transfer phenomena resultant from complex exit air flow distribution. Local peaks in heat transfer coefficient have been shown to be directly related to the air flow and fan motor support interaction. Optimum locations for discrete heat source positioning have been identified which are a function of fan to plate spacing and independent of fan rotational speed when the Reynolds number effect is not apparent.

  10. Irradiation behavior of experimental miniature uranium silicide fuel plates

    International Nuclear Information System (INIS)

    Hofman, Gerard L.; Neimark, L.A.; Mattas, R.F.

    1983-01-01

    Uranium silicides, because of their relatively high uranium density, were selected as candidate dispersion fuels for the higher fuel densities required in the Reduced Enrichment Research and Test Reactor (RERTR) Program. Irradiation experience with this type of fuel, however, was limited to relatively modest fission densities in the bulk form, on the order of 7 x 10 20 cm -3 , far short of he approximately 20 x 10 20 cm -3 goal established for the RERTR Program. The purpose of the irradiation experiments on silicide fuels in the ORR, therefore, was to investigate the intrinsic irradiation behavior of uranium silicide as a dispersion fuel. Of particular interest was the interaction between the silicide particles and the aluminum matrix, the swelling behavior of the silicide particles, and the maximum volume fraction of silicide particles that could be contained in the aluminum matrix. The first group of experimental 'mini' fuel plates have recently reached the program's goal burnup and are in various stages of examination. Although the results to date indicate some limitations, it appears that within the range of parameters examined thus far the uranium silicide dispersion holds promise for satisfying most of the needs of the RERTR Program. The twelve experimental silicide dispersion fuel plates that were irradiated to approximately their goal exposure show the 30-vol % U 3 Si-Al plates to be in a stage of relatively rapid fission-gas-driven swelling at a fission density of 2 x 10 20 cm -3 . This fuel swelling will likely result in unacceptably large plate-thickness increases. The U 3 Si plates appear to be superior in this respect; however, they, too, are starting to move into the rapid fuel-swelling stage. Analysis of the currently available post irradiation data indicates that a 40-vol % dispersed fuel may offer an acceptable margin to the onset of unstable thickness changes at exposures of 2 x 10 21 fission/cm 3 . The interdiffusion between fuel and matrix

  11. Numerical Study on the Structural Performance of Steel Beams with Slant End-plate Connections

    Directory of Open Access Journals (Sweden)

    Farshad Zahmatkesh

    Full Text Available Abstract Thermal effects can be one of the most harmful conditions that any steel structure should expect throughout its service life. To counteract this effect, a new beam, with a capability to dissipate thermally induced axial force by slanting of end-plate connection at both ends, is proposed. The beam was examined in terms of its elastic mechanical behavior under symmetric transverse load in presence of an elevated temperature by means of direct stiffness finite element model. The performance of such connection is defined under two resisting mechanisms; by friction force dissipation between faces of slant connection and by small upward crawling on slant plane. The presented numerical method is relatively easy and useful to evaluate the behavior of the proposed beam of various dimensions at different temperatures. Its applicability is evident through satisfactory results verification with those from experimental, analytical and commercially available finite element software. Based on the good agreement between theoretical and experimental methods, a series of design curves were developed as a safe-practical range for the slant end-plate connections which are depend on the conditions of the connection.

  12. Weight functions for the determination of stress intensity factor and T-stress for edge-cracked plates with built-in ends

    International Nuclear Information System (INIS)

    Li, J.; Wang, X.; Tan, C.L.

    2004-01-01

    This paper presents the weight functions for the determination of the stress intensity factor and T-stress solutions for edge-cracked plates with built-in ends under complex stress distributions. First, a compliance analysis approach is used to calculate stress intensity factor and T-stress for edge cracks in finite width plates with built-in ends with uniform or linear stress distributions acting on the crack face. The results serve as the reference solutions for the next step in which the approaches of deriving weight functions from reference stress intensity factor and T-stress solutions developed for stress boundary conditions are extended to obtain the corresponding weight functions for edge-cracked plates with built-in ends. Finite element analysis is conducted to validate the derived solutions. The weight functions derived are suitable for obtaining stress intensity factors and T-stress solutions under any complex stress field

  13. Examination system utilizing ionizing radiation and a flexible, miniature radiation detector probe

    Science.gov (United States)

    Majewski, Stanislaw; Kross, Brian J.; Zorn, Carl J.; Majewski, Lukasz A.

    1996-01-01

    An optimized examination system and method based on the Reverse Geometry X-Ray.RTM. (RGX.RTM.) radiography technique are presented. The examination system comprises a radiation source, at least one flexible, miniature radiation detector probe positioned in appropriate proximity to the object to be examined and to the radiation source with the object located between the source and the probe, a photodetector device attachable to an end of the miniature radiation probe, and a control unit integrated with a display device connected to the photodetector device. The miniature radiation detector probe comprises a scintillation element, a flexible light guide having a first end optically coupled to the scintillation element and having a second end attachable to the photodetector device, and an opaque, environmentally-resistant sheath surrounding the flexible light guide. The probe may be portable and insertable, or may be fixed in place within the object to be examined. An enclosed, flexible, liquid light guide is also presented, which comprises a thin-walled flexible tube, a liquid, preferably mineral oil, contained within the tube, a scintillation element located at a first end of the tube, closures located at both ends of the tube, and an opaque, environmentally-resistant sheath surrounding the flexible tube. The examination system and method have applications in non-destructive material testing for voids, cracks, and corrosion, and may be used in areas containing hazardous materials. In addition, the system and method have applications for medical and dental imaging.

  14. Narrative Metamorphosis Through Images: The Case of Opening Miniatures in the Estoire del

    Directory of Open Access Journals (Sweden)

    Miha Zor

    2015-12-01

    Full Text Available The article deals with pictorial metamorphosis in the opening pages of two early 14th-century manuscripts of the Estoire del saint Graal. Firstly, the episodes depicted are analysed iconographically and formally. Secondly, it explores how pictorial narrative is established in the multi-compartmentalised miniature, that is how the images are linked internally in order to convey a narrative that has its beginning and its ending. Thirdly, it is shown how the images in the opening miniature communicate with other miniatures in the manuscript and how the course of interpretation, signaled by the opening miniature, is succeeded and confirmed by the selection of episodes which are subsequently depicted, as well as by the way in which the episodes depicted are pictorially interpreted.

  15. Bend testing for miniature disks

    International Nuclear Information System (INIS)

    Huang, F.H.; Hamilton, M.L.; Wire, G.L.

    1982-01-01

    A bend test was developed to obtain ductility measurements on a large number of alloy variants being irradiated in the form of miniature disks. Experimental results were shown to be in agreement with a theoretical analysis of the bend configuration. Disk specimens fabricated from the unstrained grip ends of previously tested tensile specimens were used for calibration purposes; bend ductilities and tensile ductilities were in good agreement. The criterion for estimating ductility was judged acceptable for screening purposes

  16. Preliminary studies of microchannel plate photomultiplier tube neutron detectors for flight test applications

    International Nuclear Information System (INIS)

    Dolan, K.W.

    1978-10-01

    Electrical, mechanical, thermal, and neutron response data indicate that microchannel plate photomultiplier tubes are viable candidates as miniature, ruggedized neutron detectors for flight test applications in future weapon systems

  17. Micro-channel plates and vacuum detectors

    Energy Technology Data Exchange (ETDEWEB)

    Gys, T., E-mail: Thierry.Gys@cern.ch

    2015-07-01

    A micro-channel plate is an array of miniature electron multipliers that are each acting as a continuous dynode chain. The compact channel structure results in high spatial and time resolutions and robustness to magnetic fields. Micro-channel plates have been originally developed for night vision applications and integrated as an amplification element in image intensifiers. These devices show single-photon sensitivity with very low noise and have been used as such for scintillating fiber tracker readout in high-energy physics experiments. Given their very short transit time spread, micro-channel plate photomultiplier tubes are also being used in time-of-flight and particle identification detectors. The present paper will cover the history of the micro-channel plate development, basic features, and some of their applications. Emphasis will be put on various new manufacturing processes that have been developed over the last few years, and that result in a significant improvement in terms of efficiency, noise, and lifetime performance.

  18.  An Uncommon Presentation of Giant Cell Tumor

    Directory of Open Access Journals (Sweden)

    Gopal Malhotra

    2011-09-01

    Full Text Available  Giant Cell Tumors commonly occur at the ends of long bones. However in rare cases, they can occur in the bones of the hands and feet. Tumors in these locations occur in younger patients; in addition, these tumors are more commonly multifocal and are associated with a higher risk for local recurrence than tumors at the ends of long bones. Since lesions in the small bones may be multifocal, a patient with a giant cell tumor of the small bones should undergo a skeletal survey to exclude similar lesions elsewhere. Primary surgical treatment ranges from curettage or excision with or without bone grafting to amputation. The success of surgical treatment depends on the completeness with which the tumor was removed. We are presenting a case report of a 34 year old female, who presented with a swelling in the right hand, following trauma. X-ray of the hand showed an osteolytic expansile lesion at the base of the 1st metacarpal bone. The lesion was initially curetted and then treated by local resection with bone grafting. Histological examination revealed a typical benign giant cell tumor composed of closely packed stromal cells with a variable admixture of giant cells. Follow up at the end of one year did not reveal any recurrence of the tumor.

  19. Treatment of a partially thrombosed giant aneurysm of the vertebral artery by aneurysm trapping and direct vertebral artery-posterior inferior cerebellar artery end-to-end anastomosis: technical case report.

    Science.gov (United States)

    Benes, Ludwig; Kappus, Christoph; Sure, Ulrich; Bertalanffy, Helmut

    2006-07-01

    The purpose of this article is to focus for the first time on the operative management of a direct vertebral artery (VA)-posterior inferior cerebellar artery (PICA) end-to-end anastomosis in a partially thrombosed giant VA-PICA-complex aneurysm and to underline its usefulness as an additional treatment option. The operative technique of a direct VA-PICA end-to-end anatomosis is described in detail. The VA was entering the large aneurysm sack. Distally, the PICA originated from the aneurysm sack-VA-complex. The donor and recipient vessel were cut close to the aneurysm. Whereas the VA was cut in a straight manner, the PICA was cut at an oblique 45-degree angle to enlarge the vascular end diameter. Vessel ends were flushed with heparinized saline and sutured. The thrombotic material inside the aneurysm sack was removed and the distal VA clipped, leaving the anterior spinal artery and brainstem perforators free. The patient regained consciousness without additional morbidity. Magnetic resonance imaging scans revealed a completely decompressed brainstem without infarction. The postoperative angiograms demonstrated a good filling of the anastomosed PICA. Despite the caliber mistmatch of these two vessels the direct VA-PICA end-to-end anastomosis provides an accurate alternative in addition to other anastomoses and bypass techniques, when donor and recipient vessels are suitable and medullary perforators do not have to be disrupted.

  20. Effect of KOH concentration and anions on the performance of Ni-H2 battery positive plate

    Science.gov (United States)

    Vaidyanathan, H.; Robbins, Kathleen; Gopalakrishna, Rao M.

    1995-01-01

    The capacity and voltage behavior of electrochemically impregnated sintered nickel positive plates was examined by galavanostatic charging; and discharging in a flooded electrolyte cell. Three different concentrations of KOH (40 percent, 31 percent, and 26 percent) and 31 percent KOH containing dissolved nitrate, sulfate or silicate were investigated. The end of charge voltage at C/10 charge and at 10 C showed the following order: 40 percent KOH is greater than 31 percent KOH alone and in the presence of the anions greater than 26 percent KOE. The middischarge voltage at C/2 discharge was higher in 26 percent KOH, almost the same for 31 percent KOH with and without the added contaminants and much lower for 40 percent KOH. The plate capacity was marginally affected by cycling in all cases except for 40 percent KOH where the capacity declined after 1000 cycles at 80 percent DOD. At the end of cycling the plate tested in the presence of sulfate and silicate experienced measurable weight loss as a result of active material extrusion. Cyclic voltammetry of miniature electrodes in 31 percent KOH showed that the second oxidation peak that corresponds to the formation of a different phase of oxidized Ni has a lower peak current at -5 C compared to 25 C and oxygen evolution occurs a higher potential at -5 C. The reduction peak (discharge reaction) is more polarized at 25 C compared to -5 C. The presence of silicate alters the potentials only marginally. The implications of these results in plate treatment and low temperature operation are discussed.

  1. Failure Analysis of a Nickel-Plated Electronic Connector Due to Salt-Induced Corrosion (ENGE 2014).

    Science.gov (United States)

    Lee, Na-Ri; Choi, Hyoung-Seuk; Choi, Duck-Kyun

    2015-10-01

    When electronic connectors in mobile devices are miniaturized, the thickness of plating decreases. However, this thin plating is expected to decrease the life of the connector due to problems with corrosion. In this study, salt spray aging tests were performed on miniaturized nickel-plated stainless steel electronic connectors to observe failure mechanisms in realistic environments. The tests were performed three times using a 5% NaCl solution in an atmosphere of 45 °C; each test included several cycles where one cycle was one 24-h period consisting of 8 h of salt spray and 16 h without salt spray. The nickel-plating layers were periodically observed by electron probe X-ray micro-analyzer, wavelength dispersive spectroscopy, and field-emission scanning electron microscopy to analyze and identify the corrosion mechanism. We found that the primary failure mode of the nickel plating is blistering and delamination. The corrosion mechanism is typically a chain reaction of several corrosion mechanisms: pitting corrosion --> stress corrosion cracking --> hydrogen-induced cracking --> blistering and delamination. Finally, we discuss countermeasures to prevent corrosion of the nickel layer based on the corrosion mechanisms identified in this study.

  2. Lamination and end plate design studies of SSC Low Energy Booster magnet prototypes

    International Nuclear Information System (INIS)

    Li, N.

    1993-01-01

    The LEB machine includes six kinds of laminated magnets and 4 kinds of laminations. The main quadrupole magnet and low field and high field corrector quadrupoles use the same lamination shape. The chromaticity sextupole, corrector dipole, and main dipole have different lamination designs. To test the physical design and production procedure for the magnets, it is necessary to build 2 or 3 prototypes for each kind of magnet. The ZVI plant in Moscow, manufactured all 4 kinds of lamination punching dies for the LEB magnets. Each die takes 3 to 5 months to fabricate. SSCL manufactured laser cut laminated magnet prototypes in the SSC shop at the same time. Since the LEB cycles at 10 Hz, the high frequency current and laminated end plate design causes a delamination problem on the magnet end. This problem is of concern and will be addressed

  3. High-throughput isolation of giant viruses in liquid medium using automated flow cytometry and fluorescence staining.

    Directory of Open Access Journals (Sweden)

    Jacques Yaacoub Bou Khalil

    2016-01-01

    Full Text Available The isolation of giant viruses using amoeba co-culture is tedious and fastidious. Recently, the procedure was successfully associated with a method that detects amoebal lysis on agar plates. However, the procedure remains time-consuming and is limited to protozoa growing on agar. We present here advances for the isolation of giant viruses. A high-throughput automated method based on flow cytometry and fluorescent staining was used to detect the presence of giant viruses in liquid medium. Development was carried out with the Acanthamoeba polyphaga strain widely used in past and current co-culture experiments. The proof of concept was validated with virus suspensions: artificially contaminated samples but also environmental samples from which viruses were previously isolated. After validating the technique, and fortuitously isolating a new Mimivirus, we automated the technique on 96-well plates and tested it on clinical and environmental samples using other protozoa. This allowed us to detect more than ten strains of previously known species of giant viruses and 7 new strains of a new virus lineage. This automated high-throughput method demonstrated significant time saving, and higher sensitivity than older techniques. It thus creates the means to isolate giant viruses at high speed.

  4. Plating on difficult-to-plate metals: what's new

    International Nuclear Information System (INIS)

    Wiesner, H.J.

    1980-01-01

    Some of the changes since 1970 in procedures for plating on such materials as titanium, molybdenum, silicon, aluminum, and gallium arsenide are summarized. While basic procedures for plating some of these materials were developed as many as 30 to 40 years ago, changes in the end uses of the plated products have necessitated new plating processes. In some cases, vacuum techniques - such as ion bombardment, ion implantation, and vacuum metallization - have been introduced to improve the adhesion of electrodeposits. In other cases, these techniques have been used to deposit materials upon which electrodeposits are required

  5. Giant magnetic anisotropy of heavy p-elements on high-symmetry substrates: a new paradigm for supported nanostructures

    Science.gov (United States)

    Pang, Rui; Deng, Bei; Shi, Xingqiang; Zheng, Xiaohong

    2018-04-01

    Nanostructures with giant magnetic anisotropy energies (MAEs) are desired in designing miniaturized magnetic storage and quantum computing devices. Previous works focused mainly on materials or elements with d electrons. Here, by taking Bi–X(X = In, Tl, Ge, Sn, Pb) adsorbed on nitrogenized divacancy of graphene and Bi atoms adsorbed on MgO(100) as examples, through ab initio and model calculations, we propose that special p-element dimers and single-adatoms on symmetry-matched substrates possess giant atomic MAEs of 72–200 meV, and has room temperature structural stability. The huge MAEs originate from the p-orbital degeneracy around the Fermi level in a symmetry-matched surface ligand field and the lifting of this degeneracy when spin–orbit interaction (SOI) is taken into account. Especially, we developed a simplified quantum mechanical model for the design principles of giant MAEs of supported magnetic adatoms and dimers. Thus, our discoveries and mechanisms provide a new paradigm to design giant atomic MAE of p electrons in supported nanostructures.

  6. Oscillatory flow at the end of parallel-plate stacks: phenomenological and similarity analysis

    International Nuclear Information System (INIS)

    Mao Xiaoan; Jaworski, Artur J

    2010-01-01

    This paper addresses the physics of the oscillatory flow in the vicinity of a series of parallel plates forming geometrically identical channels. This type of flow is particularly relevant to thermoacoustic engines and refrigerators, where a reciprocating flow is responsible for the desirable energy transfer, but it is also of interest to general fluid mechanics of oscillatory flows past bluff bodies. In this paper, the physics of an acoustically induced flow past a series of plates in an isothermal condition is studied in detail using the data provided by PIV imaging. Particular attention is given to the analysis of the wake flow during the ejection part of the flow cycle, where either closed recirculating vortices or alternating vortex shedding can be observed. This is followed by a similarity analysis of the governing Navier-Stokes equations in order to derive the similarity criteria governing the wake flow behaviour. To this end, similarity numbers including two types of Reynolds number, the Keulegan-Carpenter number and a non-dimensional stack configuration parameter, d/h, are considered and their influence on the phenomena are discussed.

  7. Plating end fittings to reduce hydrogen ingress at rolled joints in CANDU reactors

    International Nuclear Information System (INIS)

    White, A.J.; Urbanic, V.F.; Bahurmuz, A.A.; Clendening, W.R.; Joynes, R.; McDougall, G.M.; Skinner, B.C.; Venkatapathi, S.

    1993-10-01

    Zr-2.5Nb pressure tubes in CANDU nuclear reactors absorb hydrogen at a low rate from the primary heat transport water circulated through the tubes. Extra hydrogen is picked up at the rolled joints that connect the pressure tubes to out-of-core steel piping. This enhanced ingress may contribute to pressure-tube cracking at incorrectly assembled joints. The risk of pressure-tube failure has been decreased by ensuring correct joint assembly, and could be further decreased by reducing hydrogen ingress at rolled joints. This paper reviews progress toward using plated end fittings to reduce rolled-joint hydrogen ingress

  8. Fabrication of a miniature diamond grinding tool using a hybrid process of micro-EDM and co-deposition

    International Nuclear Information System (INIS)

    Chen, Shun-Tong; Lai, Yun-Cheng; Liu, Ching-Chang

    2008-01-01

    A novel miniature diamond grinding tool usable for the precise micro-grinding of miniature parts is presented. A hybrid process that combines 'micro-EDM' with 'precision co-deposition' is proposed. The metal substrate is micro-EDMed to a 50 µm diameter and micro diamonds with 0–2 µm grains are 'electroformed' on the substrate surface, producing a miniature multilayered grinding tool. Nickel and diamond act as binders and cutters, respectively. A partition plate with an array of drilled holes is designed to ensure good convection in the electroforming solution. The dispersion of diamond grains and displacement of nickel ions are noticeably improved. A miniature funnel mould enables the diamond grains to converge towards the cathode to increase their deposition probability on the substrate, thereby improving their distribution on the substrate surface. A micro ZrO 2 ceramic ferrule is finely ground by the developed grinding tool and then yields a surface roughness of R a = 0.085 µm. The proposed approach is applied during the final machining process

  9. Performance test of miniature heat exchangers with microchannels

    International Nuclear Information System (INIS)

    Hong, Yong Ju; Koh, Deuk Yong

    2005-01-01

    Etched microchannel heat exchanger, a subfield within MEMS, has high heat flux capability. This capability makes microchannels well-suited for a wide variety of application of cooling and chemical reaction. In this study, counter flow type miniature heat exchangers, which have flat metal plates with chemically etched microchannels, were manufactured by brazing method. Four type of the heat exchangers, which have straight microchannels, wavy shape microchannels, pin-fin channels and serpentine shape microchannels, were investigated to compare their thermal and hydraulic performance. Gas to gas heat exchange experiments were performed to measure the pressure drop and effectiveness of the heat exchangers at given gas flow rates and temperature difference

  10. Four-plate piezoelectric actuator driving a large-diameter special optical fiber for nonlinear optical microendoscopy.

    Science.gov (United States)

    Wang, Ying; Li, Zhi; Liang, Xiaobao; Fu, Ling

    2016-08-22

    In nonlinear optical microendoscope (NOME), a fiber with excellent optical characteristics and a miniature scanning mechanism at the distal end are two key components. Double-clad fibers (DCFs) and double-clad photonic crystal fibers (DCPCFs) have shown great optical characteristics but limited vibration amplitude due to large diameter. Besides reducing the damping of fiber cantilever, optimizing the structural of the actuator for lower energy dissipation also contributes to better driving capability. This paper presented an optimized actuator for driving a particular fiber cantilever in the view point of energy. Firstly, deformation energy of a bending fiber cantilever operating in resonant mode is investigated. Secondly, strain and stress analyses revealed that the four-plate actuator achieved lower energy dissipation. Then, finite-element simulations showed that the large-diameter fiber yielded an adequate vibration amplitude driven by a four-plate actuator, which was confirmed by experiments of our home-made four-plate actuator prototypes. Additionally, a NOME based on a DCPCF with a diameter of 350 μm driven by four-plate piezoelectric actuator has been developed. The NOME can excite and collect intrinsic second-harmonic and two-photon fluorescence signals with the excitation power of 10-30 mW and an adequate field of view of 200 μm, which suggest great potential applications in neuroscience and clinical diagnoses.

  11. Effect of KOH Concentration and Anions on the Performance of a Ni-H2 Battery Positive Plate

    Science.gov (United States)

    Vaidyanathan, Hari; Robbins, Kathleen; Gopalakrishna, M. Rao

    1996-01-01

    The capacity and voltage behavior of electrochemically impregnated sintered nickel positive plates was examined by galvanostatic charging and discharging in a flooded electrolyte cell. Three different concentrations of potassium hydroxide (KOH) (40, 31, and 26 percent) and 31 percent KOH containing dissolved nitrate, sulfate, or silicate were investigated. The end-of-charge voltage at C/10 charge and at 10 degrees C showed the following order: 40 percent KOH greater than 31 percent KOH alone and in the presence of the anions greater than 26 percent KOH. The mid discharge voltage at C/2 discharge was higher in 26 percent KOH, almost the same for 31 percent KOH with and without added contaminants, and much lower for 40 percent KOH. The plate capacity was marginally affected by cycling in all cases except for 40 percent KOH, where the capacity declined after 1,000 cycles at 80 percent depth of discharge (DOD). At the end of cycling, all the plates tested experienced a weight loss, except in the case of 31 percent KOH, as a result of active material extrusion. Cyclic voltammetry of miniature electrodes in 31 percent KOH showed that the cathodic peak potentials are less polarized in the presence and absence of silicate at -5 degrees C compared to 25 degrees C indicating a slightly higher voltage during discharge in a Ni-H2 battery. Futhermore, the features of the current-potential profile were practically unchanged in the presence of silicate.

  12. Realization of Miniaturized Multi-/Wideband Microwave Front-Ends

    Science.gov (United States)

    Al Shamaileh, Khair A.

    The ever-growing demand toward designing microwave front-end components with enhanced access to the radio spectrum (e.g., multi-/wideband functionality) and improved physical features (e.g., miniaturized circuitry, ease and cost of fabrication) is becoming more paramount than ever before. This dissertation proposes new design methodologies, simulations, and experimental validations of passive front-ends (i.e., antennas, couplers, dividers) at microwave frequencies. The presented design concepts optimize both electrical and physical characteristics without degrading the intended performance. The developed designs are essential to the upcoming wireless technologies. The first proposed component is a compact ultra-wideband (UWB) Wilkinson power divider (WPD). The design procedure is accomplished by replacing the uniform transmission lines in each arm of the conventional single-frequency divider with impedance-varying profiles governed by a truncated Fourier series. While such non-uniform transmission lines (NTLs) are obtained through the even-mode analysis, three isolation resistors are optimized in the odd-mode circuit to achieve proper isolation and output ports matching over the frequency range of interest. The proposed design methodology is systematic, and results in single-layered and compact structures. For verification purposes, an equal split WPD is designed, simulated, and measured. The obtained results show that the input and output ports matching as well as the isolation between the output ports are below --10 dB; whereas the transmission parameters vary between --3.2 dB and --5 dB across the 3.1--10.6 GHz band. The designed divider is expected to find applications in UWB antenna diversity, multiple-input-multiple-output (MIMO) schemes, and antenna arrays feeding networks. The second proposed component is a wideband multi-way Bagley power divider (BPD). Wideband functionality is achieved by replacing the single-frequency matching uniform microstrip lines in

  13. Nuclear fuel element end fitting

    International Nuclear Information System (INIS)

    Jabsen, F.S.

    1980-01-01

    An invention is described whereby end fittings are formed from lattices of mutually perpendicular plates. At the plate intersections, sockets are secured to the end fittings in a manner that permits the longitudinal axes of each of the sockets to align with the respective lines of intersection of the plates. The sockets all protrude above one of the surfaces of the end fitting. Further, a detent is formed in the proturding sides of each of the sockets. Annular grooves are formed in each of the ends of the fuel rods that are to be mounted between the end fittings. The socket detents protrude into the respective annular grooves, thus engaging the grooves and retaining the fuel rods and end fittings in one integral structure. (auth)

  14. Complex social waves of giant honeybees provoked by a dummy wasp support the special-agent hypothesis.

    Science.gov (United States)

    Kastberger, Gerald; Weihmann, Frank; Hoetzl, Thomas

    2010-03-01

    The social waves in giant honeybees termed as shimmering are more complex than mexican waves. it has been demonstrated1 that shimmering is triggered by special agents at the nest surface. in this paper, we have used a nest that originated by amalgamation of two previously separated nests and stimulated waves by a dummy wasp moved on a miniature cable car. we illustrate the plausibility of the special-agent hypothesis1 also for complex shimmering processes.

  15. Complex social waves of giant honeybees provoked by a dummy wasp support the special-agent hypothesis

    OpenAIRE

    Kastberger, Gerald; Weihmann, Frank; Hoetzl, Thomas

    2010-01-01

    The social waves in giant honeybees termed as shimmering are more complex than mexican waves. it has been demonstrated1 that shimmering is triggered by special agents at the nest surface. in this paper, we have used a nest that originated by amalgamation of two previously separated nests and stimulated waves by a dummy wasp moved on a miniature cable car. we illustrate the plausibility of the special-agent hypothesis1 also for complex shimmering processes.

  16. Low-Power Receive-Electronics for a Miniature 3D Ultrasound Probe

    NARCIS (Netherlands)

    Yu, Z.

    2012-01-01

    This thesis describes the design of a front-end application-specific integrated circuit (ASIC), which will be put into the tip of a miniature ultrasound probe for 3D Trans-Esophageal Echocardiography (TEE). To enable 3D TEE, a matrix piezoelectric ultrasound transducer with more than 2000 elements

  17. Detection of leakage magnetic flux from near-side and far-side defects in carbon steel plates using a giant magneto-resistive sensor

    International Nuclear Information System (INIS)

    Singh, W Sharatchandra; Rao, B P C; Vaidyanathan, S; Jayakumar, T; Raj, Baldev

    2008-01-01

    Giant magneto-resistive (GMR) sensors are attractive for magnetic flux leakage measurements, especially for the detection of shallow near-side cracks and deeply located defects. An optimized measurement system with magnetic yoke, GMR sensor and selective amplifier has been devised to detect the tangential component of leakage flux from various near-side notches and far-side notches (widths 0.5 mm and 1.0 mm, respectively) in 12 mm thick carbon steel plates. Far-side notches located at nearly 11 mm below the measurement surface have been detected with a good signal-to-noise ratio. The performance of the GMR sensor with lift off has also been studied for possible non-contact examination of hot surfaces and a lift off of 2 mm is expected to ensure the saturation-free detection of near-side as well as far-side notches

  18. Analysis of nonlinear elastic behavior in miniature pneumatic artificial muscles

    Science.gov (United States)

    Hocking, Erica G.; Wereley, Norman M.

    2013-01-01

    Pneumatic artificial muscles (PAMs) are well known for their excellent actuator characteristics, including high specific work, specific power, and power density. Recent research has focused on miniaturizing this pneumatic actuator technology in order to develop PAMs for use in small-scale mechanical systems, such as those found in robotic or aerospace applications. The first step in implementing these miniature PAMs was to design and characterize the actuator. To that end, this study presents the manufacturing process, experimental characterization, and analytical modeling of PAMs with millimeter-scale diameters. A fabrication method was developed to consistently produce low-cost, high performance, miniature PAMs using commercially available materials. The quasi-static behavior of these PAMs was determined through experimentation on a single actuator with an active length of 39.16 mm (1.54 in) and a diameter of 4.13 mm (0.1625 in). Testing revealed the PAM’s full evolution of force with displacement for operating pressures ranging from 207 to 552 kPa (30-80 psi in 10 psi increments), as well as the blocked force and free contraction at each pressure. Three key nonlinear phenomena were observed: nonlinear PAM stiffness, hysteresis of the force versus displacement response for a given pressure, and a pressure deadband. To address the analysis of the nonlinear response of these miniature PAMs, a nonlinear stress versus strain model, a hysteresis model, and a pressure bias are introduced into a previously developed force balance analysis. Parameters of these nonlinear model refinements are identified from the measured force versus displacement data. This improved nonlinear force balance model is shown to capture the full actuation behavior of the miniature PAMs at each operating pressure and reconstruct miniature PAM response with much more accuracy than previously possible.

  19. Analysis of nonlinear elastic behavior in miniature pneumatic artificial muscles

    International Nuclear Information System (INIS)

    Hocking, Erica G; Wereley, Norman M

    2013-01-01

    Pneumatic artificial muscles (PAMs) are well known for their excellent actuator characteristics, including high specific work, specific power, and power density. Recent research has focused on miniaturizing this pneumatic actuator technology in order to develop PAMs for use in small-scale mechanical systems, such as those found in robotic or aerospace applications. The first step in implementing these miniature PAMs was to design and characterize the actuator. To that end, this study presents the manufacturing process, experimental characterization, and analytical modeling of PAMs with millimeter-scale diameters. A fabrication method was developed to consistently produce low-cost, high performance, miniature PAMs using commercially available materials. The quasi-static behavior of these PAMs was determined through experimentation on a single actuator with an active length of 39.16 mm (1.54 in) and a diameter of 4.13 mm (0.1625 in). Testing revealed the PAM’s full evolution of force with displacement for operating pressures ranging from 207 to 552 kPa (30–80 psi in 10 psi increments), as well as the blocked force and free contraction at each pressure. Three key nonlinear phenomena were observed: nonlinear PAM stiffness, hysteresis of the force versus displacement response for a given pressure, and a pressure deadband. To address the analysis of the nonlinear response of these miniature PAMs, a nonlinear stress versus strain model, a hysteresis model, and a pressure bias are introduced into a previously developed force balance analysis. Parameters of these nonlinear model refinements are identified from the measured force versus displacement data. This improved nonlinear force balance model is shown to capture the full actuation behavior of the miniature PAMs at each operating pressure and reconstruct miniature PAM response with much more accuracy than previously possible. (paper)

  20. Bio-inspired Miniature Suction Cups Actuated by Shape Memory Alloy

    Directory of Open Access Journals (Sweden)

    Hu Bing-shan

    2010-02-01

    Full Text Available Wall climbing robots using negative pressure suction always employ air pumps which have great noise and large volume. Two prototypes of bio-inspired miniature suction cup actuated by shape memory alloy (SMA are designed based on studying characteristics of biologic suction apparatuses, and the suction cups in this paper can be used as adhesion mechanisms for miniature wall climbing robots without air pumps. The first prototype with a two-way shape memory effect (TWSME extension TiNi spring imitates the piston structure of the stalked sucker; the second one actuated by a one way SMA actuator with a bias has a basic structure of stiff margin, guiding element, leader and elastic element. Analytical model of the second prototype is founded considering the constitutive model of the SMA actuator, the deflection of the thin elastic plate under compound load and the thermo-dynamic model of the sealed air cavity. Experiments are done to test their suction characteristics, and the analytical model of the second prototype is simulated on Matlab/simulink platform and validated by experiments.

  1. Bio-inspired Miniature Suction Cups Actuated by Shape Memory Alloy

    Directory of Open Access Journals (Sweden)

    Hu Bing-Shan

    2009-09-01

    Full Text Available Wall climbing robots using negative pressure suction always employ air pumps which have great noise and large volume. Two prototypes of bio-inspired miniature suction cup actuated by shape memory alloy (SMA are designed based on studying characteristics of biologic suction apparatuses, and the suction cups in this paper can be used as adhesion mechanisms for miniature wall climbing robots without air pumps. The first prototype with a two-way shape memory effect (TWSME extension TiNi spring imitates the piston structure of the stalked sucker; the second one actuated by a one way SMA actuator with a bias has a basic structure of stiff margin, guiding element, leader and elastic element. Analytical model of the second prototype is founded considering the constitutive model of the SMA actuator, the deflection of the thin elastic plate under compound load and the thermo-dynamic model of the sealed air cavity. Experiments are done to test their suction characteristics, and the analytical model of the second prototype is simulated on Matlab/simulink platform and validated by experiments.

  2. Search for near-infrared counterparts of IRAS embedded sources in the M17 SW giant molecular cloud

    International Nuclear Information System (INIS)

    Elmegreen, D.M.; Phillips, J.; Beck, K.; Thomas, H.; Howard, J.

    1988-01-01

    Wide-field near-infrared and blue band plates of the region containing the M17 giant molecular cloud complex have been blinked to locate bright near-infrared stars that may be embedded in the M17 SW giant molecular cloud. Twenty such stars coincided with the positions of IRAS point sources that appeared embedded based on color-color diagrams. Some of these stars may be the sources of the infrared luminosities. Of the 20 stars, seven were too faint to appear on the B band plate. The optical magnitudes and colors determined from the plate image diameters were measured for the other 13 coincident stars; they are most likely upper main-sequence or pre-main-sequence stars with extinctions of 7 mag. The IRAS luminosity-temperature diagram indicates that the embedded sources in M17 are more massive than those in the Orion cloud. 35 references

  3. METHOD OF MAKING AND PLATE CONNECTION

    Science.gov (United States)

    Patriarca, P.; Shubert, C.E.; Slaughter, G.M.

    1963-02-26

    This invention relates to a method of joining, by welding or brazing, a tube to a plate, particularly where the tube and the plate are of different thickness or have different thermal conductivities and are subject to high temperatures. In this method the tube is inserted in the core of a plate containing an annular groove in its back face concentric with the bore and in communication with the bore. One end of the tube is welded substantially flush with the front end of the plate. Brazing alloy is placed in the groove on the back face of the plate and heat is applied to the plate and tube to melt the brazing alloy to permit the alloy to flow into the bore and bond the tube to the plate. (AEC)

  4. Robot Arm with Tendon Connector Plate and Linear Actuator

    Science.gov (United States)

    Ihrke, Chris A. (Inventor); Diftler, Myron A. (Inventor); Bridgwater, Lyndon (Inventor); Nguyen, Vienny (Inventor); Millerman, Alexander (Inventor)

    2014-01-01

    A robotic system includes a tendon-driven end effector, a linear actuator, a flexible tendon, and a plate assembly. The linear actuator assembly has a servo motor and a drive mechanism, the latter of which translates linearly with respect to a drive axis of the servo motor in response to output torque from the servo motor. The tendon connects to the end effector and drive mechanism. The plate assembly is disposed between the linear actuator assembly and the tendon-driven end effector and includes first and second plates. The first plate has a first side that defines a boss with a center opening. The second plate defines an accurate through-slot having tendon guide channels. The first plate defines a through passage for the tendon between the center opening and a second side of the first plate. A looped end of the flexible tendon is received within the tendon guide channels.

  5. Effect of mixed adhesive joints and tapered plate on stresses in retrofitted beams bonded with a fiber-reinforced polymer plate

    International Nuclear Information System (INIS)

    Bouchikhi, A.S.; Megueni, A.; Gouasmi, S.; Boukoulda, F.B.

    2013-01-01

    Highlights: • Interface stress distribution in beams reinforced composites jointed by homogeneous adhesive. • The reduction of stresses interfaces by using the tapered plate at edges. • The reduction of stresses interfaces by using the bi-adhesive. • The reduction of stresses interfaces by combining between the tapered plate and the bi-adhesive. - Abstract: This paper focuses on the reduction of interfacial stresses when using bonded laminates in strengthening existing structures. The presence of high interfacial stresses that develop near the end of composite known as edge effect may compromise the résistance to failure of strengthened structure. It is known that the decrease of plate thickness and fitness of adhesive (Young modulus) reduces the stress concentration at plate ends. Another way to tackle the problem is proper design of the plate end shape (tapered plate) and using mixed adhesive joints (MAJs) between the adherents. In this paper, a comprehensive finite element (FE) study has been conducted to investigate the effect of mixed adhesive joints (MAJs) and tapering plate on the interfacial stress distribution in the adhesive layer in retrofitted steel beam with fiber reinforced polymer (FRP) plate, This results indicate that using the correct combination of tapering plate at the end and mixed adhesive joints can reduce the magnitude of the interfacial stresses significantly

  6. The Whole new world of miniature technology

    Energy Technology Data Exchange (ETDEWEB)

    Gillespie, L.K.

    1980-07-01

    In the past ten years, miniaturization of both electrical and mechanical parts has significantly increased. Documentation of the design and production capabilities of miniaturization in the electronics industry is well-defined. Literature on the subject of miniaturization of metal piece parts, however, is hard to find. Some of the current capabilities in the manufacture of miniature metal piece parts or miniature features in larger piece parts are discussed.

  7. Dynamically hot Super-Earths from outer giant planet scattering

    OpenAIRE

    Huang, Chelsea X.; Petrovich, Cristobal; Deibert, Emily

    2016-01-01

    The hundreds of multiple planetary systems discovered by the \\textit{Kepler} mission are typically observed to reside in close-in ($\\lesssim0.5$ AU), low-eccentricity, and low-inclination orbits. We run N-body experiments to study the effect that unstable outer ($\\gtrsim1$ AU) giant planets, whose end orbital configurations resemble those in the Radial Velocity population, have on these close-in multiple super-Earth systems. Our experiments show that the giant planets greatly reduce the multi...

  8. Congenital giant megaureter associated with ipsilateral multicystic dysplastic kidney in newborn

    Directory of Open Access Journals (Sweden)

    Rajendran Ramaswamy

    2016-01-01

    Full Text Available Congenital giant megaureter presents as abdominal mass and impose diagnostic difficulties. It can be associated with other upper urinary tract anomalies. A female newborn with antenatal diagnosis of polycystic kidneys was admitted at birth due to lower abdominal mass. Ultrasound and CT scans diagnosed a multiloculated cystic lesion in the mid and lower abdomen along with right side multicystic kidney. At laparotomy, an extaperitoneal, lobulated cystic swelling was found due to rightside giant megaureter. Its lower end was of normal caliber and orthotopic. End cutaneous ureterostomy was done. Intravenous urogram and isotope renograms showed nonfunctioning right kidney. She also had grade II vesicoureteral reflux on left side. Child suffered urinary infection twice. At 9m age, right nephroureterectomy was done. Histopathologic examination was consistent with cystic renal dysplasia and dilated ureter. This is the first case report of giant megaureter associated with ipsilateral multicystic dysplastic kidney in newborn.

  9. Reconstruction of lower end of radius using vascularized upper end of fibula

    Directory of Open Access Journals (Sweden)

    Koul Ashok

    2007-01-01

    Full Text Available Background: Giant cell tumor is a fairly common locally invasive tumor in young adults. The lower end of the radius is the second commonest site for this tumor. The most common treatment for this tumor is curettage with or without bone grafting but it carries a significant rate of recurrence. Excision is the treatment of choice, especially for cases in which the cortex has been breached. After excision of the distal end of the radius, different procedures have been described to reconstruct the defect of distal radius. These include partial arthrodesis and hemiarthroplasty using the upper end of the fibula. The upper end of the fibula has a morphological resemblance to the lower end of the radius and has been used to replace the latter. Traditionally it was used as a ′free′ (non-vascularized graft. More recently the upper end of the fibula has been transferred as a vascularized transfer for the same purpose. Though vascularized transfer should be expected to be more physiological, its superiority over the technically simpler non-vascularized transfer has not been conclusively proven. Materials and Methods: Two patients are presented who had giant cell tumor of distal radius. They underwent wide local excision and reconstruction with free vascularized upper end of the fibula. Result: Follow-up period was two and a half years and 12 months respectively. Both patients have returned to routine work. One patient has excellent functional result and the other has a good result. Conclusion: Vascularized upper end of fibula transfer is a reliable method of reconstruction for loss of the distal end of the radius that restores local anatomy and physiology.

  10. DEVELOPMENT OF HIGH-DENSITY U/AL DISPERSION PLATES FOR MO-99 PRODUCTION USING ATOMIZED URANIUM POWDER

    OpenAIRE

    RYU, HO JIN; KIM, CHANG KYU; SIM, MOONSOO; PARK, JONG MAN; LEE, JONG HYUN

    2013-01-01

    Uranium metal particle dispersion plates have been proposed as targets for Molybdenum-99 (Mo-99) production to improve the radioisotope production efficiency of conventional low enriched uranium targets. In this study, uranium powder was produced by centrifugal atomization, and miniature target plates containing uranium particles in an aluminum matrix with uranium densities up to 9 g-U/cm3 were fabricated. Additional heat treatment was applied to convert the uranium particles into UAlx compou...

  11. Miniature Optical Isolator, Phase I

    Data.gov (United States)

    National Aeronautics and Space Administration — To address NASA's need for miniature optical isolators in atom interferometry applications, Physical Optics Corporation (POC) proposes to develop a miniature optical...

  12. Annulus Fibrosus Can Strip Hyaline Cartilage End Plate from Subchondral Bone: A Study of the Intervertebral Disk in Tension.

    Science.gov (United States)

    Balkovec, Christian; Adams, Michael A; Dolan, Patricia; McGill, Stuart M

    2015-10-01

    Study Design Biomechanical study on cadaveric spines. Objective Spinal bending causes the annulus to pull vertically (axially) on the end plate, but failure mechanisms in response to this type of loading are poorly understood. Therefore, the objective of this study was to identify the weak point of the intervertebral disk in tension. Methods Cadaveric motion segments (aged 79 to 88 years) were dissected to create midsagittal blocks of tissue, with ∼10 mm of bone superior and inferior to the disk. From these blocks, 14 bone-disk-bone slices (average 4.8 mm thick) were cut in the frontal plane. Each slice was gripped by its bony ends and stretched to failure at 1 mm/s. Mode of failure was recorded using a digital camera. Results Of the 14 slices, 10 failed by the hyaline cartilage being peeled off the subchondral bone, with the failure starting opposite the lateral annulus and proceeding medially. Two slices failed by rupturing of the trabecular bone, and a further two failed in the annulus. Conclusions The hyaline cartilage-bone junction is the disk's weak link in tension. These findings provide a plausible mechanism for the appearance of bone and cartilage fragments in herniated material. Stripping cartilage from the bony end plate would result in the herniated mass containing relatively stiff cartilage that does not easily resorb.

  13. LITHIUM-RICH GIANTS IN GLOBULAR CLUSTERS

    Energy Technology Data Exchange (ETDEWEB)

    Kirby, Evan N.; Cohen, Judith G. [California Institute of Technology, 1200 E. California Boulevard, MC 249-17, Pasadena, CA 91125 (United States); Guhathakurta, Puragra [UCO/Lick Observatory and Department of Astronomy and Astrophysics, University of California, 1156 High Street, Santa Cruz, CA 95064 (United States); Zhang, Andrew J. [The Harker School, 500 Saratoga Avenue, San Jose, CA 95129 (United States); Hong, Jerry [Palo Alto High School, 50 Embarcadero Road, Palo Alto, CA, 94301 (United States); Guo, Michelle [Stanford University, 450 Serra Mall, Stanford, CA 94305 (United States); Guo, Rachel [Irvington High School, 41800 Blacow Road, Fremont, CA 94538 (United States); Cunha, Katia [Observatório Nacional, São Cristóvão Rio de Janeiro (Brazil)

    2016-03-10

    Although red giants deplete lithium on their surfaces, some giants are Li-rich. Intermediate-mass asymptotic giant branch (AGB) stars can generate Li through the Cameron–Fowler conveyor, but the existence of Li-rich, low-mass red giant branch (RGB) stars is puzzling. Globular clusters are the best sites to examine this phenomenon because it is straightforward to determine membership in the cluster and to identify the evolutionary state of each star. In 72 hours of Keck/DEIMOS exposures in 25 clusters, we found four Li-rich RGB and two Li-rich AGB stars. There were 1696 RGB and 125 AGB stars with measurements or upper limits consistent with normal abundances of Li. Hence, the frequency of Li-richness in globular clusters is (0.2 ± 0.1)% for the RGB, (1.6 ± 1.1)% for the AGB, and (0.3 ± 0.1)% for all giants. Because the Li-rich RGB stars are on the lower RGB, Li self-generation mechanisms proposed to occur at the luminosity function bump or He core flash cannot explain these four lower RGB stars. We propose the following origin for Li enrichment: (1) All luminous giants experience a brief phase of Li enrichment at the He core flash. (2) All post-RGB stars with binary companions on the lower RGB will engage in mass transfer. This scenario predicts that 0.1% of lower RGB stars will appear Li-rich due to mass transfer from a recently Li-enhanced companion. This frequency is at the lower end of our confidence interval.

  14. Stochastic bifurcation and fractal and chaos control of a giant magnetostrictive film-shape memory alloy composite cantilever plate subjected to in-plane harmonic and stochastic excitation

    International Nuclear Information System (INIS)

    Zhu, Zhiwen; Zhang, Qingxin; Xu, Jia

    2014-01-01

    Stochastic bifurcation and fractal and chaos control of a giant magnetostrictive film–shape memory alloy (GMF–SMA) composite cantilever plate subjected to in-plane harmonic and stochastic excitation were studied. Van der Pol items were improved to interpret the hysteretic phenomena of both GMF and SMA, and the nonlinear dynamic model of a GMF–SMA composite cantilever plate subjected to in-plane harmonic and stochastic excitation was developed. The probability density function of the dynamic response of the system was obtained, and the conditions of stochastic Hopf bifurcation were analyzed. The conditions of noise-induced chaotic response were obtained in the stochastic Melnikov integral method, and the fractal boundary of the safe basin of the system was provided. Finally, the chaos control strategy was proposed in the stochastic dynamic programming method. Numerical simulation shows that stochastic Hopf bifurcation and chaos appear in the parameter variation process. The boundary of the safe basin of the system has fractal characteristics, and its area decreases when the noise intensifies. The system reliability was improved through stochastic optimal control, and the safe basin area of the system increased

  15. Dr.Johnson's Dictionary in Miniature

    OpenAIRE

    Imazato, Chiaki

    1988-01-01

    More than hundred 'Johnson's' dictionaries have so far been published not only in English but in other countries, and there are numerous books and articles on Johnson's Dictionary. But few have referred to Johnson's Dictionary in Miniature; nor were there any books or articles on it. Fortunately, however, I've got one copy of Johnson's Dictionary in Miniature, which was published in 1806. Johnson's Dictionary (1755) has 41,677 entries, whereas Johnson's Dictionary in Miniature 23,439 entr...

  16. Giant linear plasmids in Streptomyces: a treasure trove of antibiotic biosynthetic clusters.

    Science.gov (United States)

    Kinashi, Haruyasu

    2011-01-01

    Many giant linear plasmids have been isolated from Streptomyces by using pulsed-field gel electrophoresis and some of them were found to carry an antibiotic biosynthetic cluster(s); SCP1 carries biosynthetic genes for methylenomycin, pSLA2-L for lankacidin and lankamycin, and pKSL for lasalocid and echinomycin. Accumulated data suggest that giant linear plasmids have played critical roles in genome evolution and horizontal transfer of secondary metabolism. In this review, I summarize typical examples of giant linear plasmids whose involvement in antibiotic production has been studied in some detail, emphasizing their finding processes and interaction with the host chromosomes. A hypothesis on horizontal transfer of secondary metabolism involving giant linear plasmids is proposed at the end.

  17. Neoclassical resonant-plateau transport calculation in an effectively axisymmetrized tandem mirror with finite end plate resistance

    International Nuclear Information System (INIS)

    Katanuma, I.; Kiwamoto, Y.; Adachi, S.; Inutake, M.; Ishii, K.; Yatsu, K.; Sawada, K.; Miyoshi, S.

    1987-05-01

    Calculations are made for neoclassical resonant-plateau transports in the geometry of the effectively axisymmetrized tandem mirror GAMMA 10 magnetic field, which has minimum B inbord anchors inside the axisymmetric plug/barrier mirror cells. Azimuthal drifts at the local non-axisymmetric regions are included. The radial potential profile is determined by solving selfconsistently the charge neutrality equation. A finite resistance connecting end plate to machine ground provides appropriate boundary conditions on the radial electrostatic potential distribution so that it can be determined uniquely. The calculation is consistent with experimental results of GAMMA 10. (author)

  18. Miniaturized microscope for high throughput screening of tumor spheroids in microfluidic devices

    Science.gov (United States)

    Uranga, Javier; Rodríguez-Pena, Alejandro; Gahigiro, Desiré; Ortiz-de-Solorzano, Carlos

    2018-02-01

    High-throughput in vitro screening of highly physiological three-dimensional cell cultures (3D-HTS) is rapidly gaining importance in preclinical studies, to study the effect of the microenvironment in tumor development, and to evaluate the efficacy of new anticancer drugs. Furthermore, it could also be envisioned the use of 3D-HTS systems in personalized anti-cancer treatment planning, based on tumor organoids or spheroids grown from tumor biopsies or isolated tumor circulating cells. Most commercial, multi-well plate based 3D-HTS systems are large, expensive, and are based on the use of multi-well plates that hardly provide a physiological environment and require the use of large amounts of biological material and reagents. In this paper we present a novel, miniaturized inverted microscope (hereinafter miniscospe), made up of low-cost, mass producible parts, that can be used to monitor the growth of living tumor cell spheroids within customized three-dimensional microfluidic platforms. Our 3D-HTS miniscope combines phase contrast imaging based on oblique back illumination technique with traditional widefield epi-fluorescence imaging, implemented using miniaturized electro-optical parts and gradient-index refraction lenses. This small (3x6x2cm), lightweight device can effectively image overtime the growth of (>200) tumor spheroids in a controlled and reproducible environment. Our miniscope can be used to acquire time-lapse images of cellular living spheroids over the course of several hours and captures their growth before and after drug treatment, to evaluate the effectiveness of the drug.

  19. DEVELOPMENT OF HIGH-DENSITY U/AL DISPERSION PLATES FOR MO-99 PRODUCTION USING ATOMIZED URANIUM POWDER

    Directory of Open Access Journals (Sweden)

    HO JIN RYU

    2013-12-01

    Full Text Available Uranium metal particle dispersion plates have been proposed as targets for Molybdenum-99 (Mo-99 production to improve the radioisotope production efficiency of conventional low enriched uranium targets. In this study, uranium powder was produced by centrifugal atomization, and miniature target plates containing uranium particles in an aluminum matrix with uranium densities up to 9 g-U/cm3 were fabricated. Additional heat treatment was applied to convert the uranium particles into UAlx compounds by a chemical reaction of the uranium particles and aluminum matrix. Thus, these target plates can be treated with the same alkaline dissolution process that is used for conventional UAlx dispersion targets, while increasing the uranium density in the target plates

  20. Giant paraganglioma in

    Directory of Open Access Journals (Sweden)

    Alka Gupta

    2017-07-01

    Full Text Available Paraganglioma is a rare neuroendocrine catecholamine producing tumour in childhood which arises outside the adrenal medulla. We present a 12 year old girl with giant paraganglioma with severe hypertension and end organ damage. Diagnosis was confirmed with 24 h urinary Vanillymandelic Acid (VMA and CT scan. Preoperative blood pressure was controlled with intravenous nitroprusside, and oral prazosin, amlodepine, labetalol and metoprolol. General anaesthesia with epidural analgesia was given. Intra operative blood pressure rise was managed with infusion of nitriglycerine (NTG, esmolol, nitroprusside and propofol.

  1. Phosphorus-31 NMR analysis of gold plating baths

    Energy Technology Data Exchange (ETDEWEB)

    Smith, R.E.

    1992-03-01

    This report describes the nuclear magnetic resonance (NMR) analysis of gold plating baths in the Micro-Miniature Electronic Assembly department of Allied-Signal Inc., Kansas City Division (KCD). The baths were analyzed for phosphorylated components. In freshly prepared gold plating baths in this department the principle compound observed is aminotrimethyl-phosphonate, or ATMP. As the bath is used in production, the ATMP breaks down; and new compounds, aminodimethylphosphonate (ADMP), aminomonomethylphosphonate, (AMMP), and inorganic phosphate (H{sub 2}PO{sub 4}{sup {minus}}), are formed. The NMR method has been used for almost three years to monitor the concentrations of the ATMP and breakdown products. In a previous report, results from January through October 1988 were reported. In this report, results from November 1988 through January 1991 are given.

  2. The miniature accelerator

    CERN Multimedia

    Antonella Del Rosso

    2015-01-01

    The image that most people have of CERN is of its enormous accelerators and their capacity to accelerate particles to extremely high energies. But thanks to some cutting-edge studies on beam dynamics and radiofrequency technology, along with innovative construction techniques, teams at CERN have now created the first module of a brand-new accelerator, which will be just 2 metres long. The potential uses of this miniature accelerator will include deployment in hospitals for the production of medical isotopes and the treatment of cancer. It’s a real David-and-Goliath story.   Serge Mathot, in charge of the construction of the "mini-RFQ", pictured with the first of the four modules that will make up the miniature accelerator. The miniature accelerator consists of a radiofrequency quadrupole (RFQ), a component found at the start of all proton accelerator chains around the world, from the smallest to the largest. The LHC is designed to produce very high-intensity beams ...

  3. Strange Animals and Creatures in Islamic Miniatures: Focusing on Miniatures of the Conference of the Birds

    Directory of Open Access Journals (Sweden)

    Neda Rohani

    2017-09-01

    Full Text Available Strange animals and creatures have always existed in every mythological culture. In Iran's pre-Islamic and post-Islamic miniatures and reliefs, there are many strange animals and creatures such as dragons and phoenix which were associated with the Iranian culture and civilization. Because of presence of these strange creatures, particularly human life, these creatures are first used in mythological life and then symbolically to express human ideas. However, these animals were present in both mythology and epics and, later in the Islamic era, in the mystical stories, educational stories and admonishing anecdotes like Sanai, Attar, and Rumi. This study tends to investigate genealogy of strange animals and creatures in ancient Iranian reliefs and their continued presence in miniatures of Islamic era as well as presence of these creatures in miniatures which are based on Attar’s Conference of the Birds. In fact, this study reviews elements and symbolic concepts of animals, allowing a deeper understanding of function of elements and symbolism in works of Iranian miniaturists. Contemplation of miniatures, icons and the relationship between literature and miniatures will lead to many results in recognition of mystical intellectual foundations. Therefore, this study tends to investigate mysterious and unknown aspects of Iranian miniatures and find their relationship with culture and stories.

  4. Rare giant cell tumor involvement of the olecranon bone

    Directory of Open Access Journals (Sweden)

    Chen Yang

    2014-01-01

    Full Text Available Giant cell tumor (GCT of bone is a relatively common benign bone lesion and is usually located in long bones, but involvement of the olecranon is extremely rare. Here, we present a case of solitary GCT of bone in the olecranon that was confirmed by preoperative needle biopsy and postoperative histological examination. The treatment included intralesional curettage, allogeneic bone grafting, and plating. At 26 months follow-up, the patient had no local recurrence.

  5. SSC collider dipole magnet end mechanical design

    International Nuclear Information System (INIS)

    Delchamps, S.W.; Bossert, R.C.; Carson, J.; Ewald, K.; Fulton, H.; Kerby, J.; Koska, W.; Strait, J.; Wake, M.; Leung, K.K.

    1991-01-01

    This paper describes the mechanical design of the ends of Superconducting Super Collider dipole magnets to be constructed and tested at Fermilab. Coil end clamps, end yoke configuration, and end plate design are discussed. Loading of the end plate by axial Lorentz forces is discussed. Relevant data from 40 mm and 50 mm aperture model dipole magnets built and tested at Fermilab are presented. In particular, the apparent influence of end clamp design on the quench behavior of model SSC dipoles is described

  6. Visual thread quality for precision miniature mechanisms

    Energy Technology Data Exchange (ETDEWEB)

    Gillespie, L.K.

    1981-04-01

    Threaded features have eight visual appearance factors which can affect their function in precision miniature mechanisms. The Bendix practice in deburring, finishing, and accepting these conditions on miniature threads is described as is their impact in assemblies of precision miniature electromechanical assemblies.

  7. SSC collider dipole magnet end mechanical design

    International Nuclear Information System (INIS)

    Delchamps, S.W.; Bossert, R.C.; Carson, J.; Ewald, K.; Fulton, H.; Kerby, J.; Koska, W.; Strait, J.; Wake, S.M.; Leung, K.K.

    1991-05-01

    This paper describes the mechanical design of the ends of Superconducting Super Collider dipole magnets to be constructed and tested at Fermilab. Coil end clamps, end yoke configuration, and end plate design are discussed. Loading of the end plate by axial Lorentz forces is discussed. Relevant data from 40 mm and 50 mm aperture model dipole magnets built and tested at Fermilab are presented. In particular, the apparent influence of end clamp design on the quench behavior of model SSC dipoles is described. 8 refs., 3 figs

  8. Advances in Miniaturized Instruments for Genomics

    Directory of Open Access Journals (Sweden)

    Cihun-Siyong Alex Gong

    2014-01-01

    Full Text Available In recent years, a lot of demonstrations of the miniaturized instruments were reported for genomic applications. They provided the advantages of miniaturization, automation, sensitivity, and specificity for the development of point-of-care diagnostics. The aim of this paper is to report on recent developments on miniaturized instruments for genomic applications. Based on the mature development of microfabrication, microfluidic systems have been demonstrated for various genomic detections. Since one of the objectives of miniaturized instruments is for the development of point-of-care device, impedimetric detection is found to be a promising technique for this purpose. An in-depth discussion of the impedimetric circuits and systems will be included to provide total consideration of the miniaturized instruments and their potential application towards real-time portable imaging in the “-omics” era. The current excellent demonstrations suggest a solid foundation for the development of practical and widespread point-of-care genomic diagnostic devices.

  9. Seasonal changes of progesterone and testosterone contents in hair of giant pandas

    International Nuclear Information System (INIS)

    Guo Dazhi; Liu Xianyi; Chen Faju

    1994-01-01

    Seasonal changes of progesterone content (PSC) in hair of three female giant pandas and testosterone content (TSC) in hair of two male giant pandas were tested by radioimmunoassay. During March to early June, PSC in two non-pregnant giant pandas (x-bar+-SD = 13.40 +- 10.06 and 10.60 +- 8.88 ng/g hair respectively) were higher than those in non-breeding season (3.07 +-1.07 and 3.20 +- 1.15 ng/g, P<0.01). PSC in a 18-year-old female giant panda remained at low levels (2.72 +- 1.49 ng/g) during March to December. In a twin-bear giant panda, PSC (6.77 +- 3.66 ng/g) appeared higher than that in non-pregnant giant pandas in non-breeding season. Around February to the end of May, TSC in two male giant pandas (1.89 +- 1.71 and 1.82 +- 1.04 ng/g respectively) were also higher than that in non-breeding season (0.98 +- 0.57 and 0.75 +- 0.39 ng/g, P<0.01). the findings from the study implied that giant panda's hair is possible to be used as a specimen to carry out steroids research in the endangered species

  10. Experimental techniques for subnanosecond resolution of laser-launched plates and impact studies

    Energy Technology Data Exchange (ETDEWEB)

    Paisley, D.L.; Warnes, R.H.; Stahl, D.B. [Los Alamos National Lab., NM (United States). Dynamic Experimentation Div.

    1994-09-01

    Miniature laser-launched plates have applications in shock wave physics, studying dynamic properties of materials and can be used to generate experimental data in a manner similar to a laboratory gas gun for one-dimensional impact experiments. Laser-launched plates have the advantage of small size, low kinetic energy, and can be launched with ubiquitous laboratory lasers. Because of the small size and high accelerations (10{sup 7}--10{sup 10} g`s), improved temporal resolution and optical non-contact methods to collect data are required. Traditional mechanical in-situ gauges would significantly impair the data quality and do not have the required time response.

  11. Total hip arthroplasty for giant cell tumour.

    Directory of Open Access Journals (Sweden)

    Kulkarni S

    1996-07-01

    Full Text Available A 32 month follow up of an uncommon case of a Giant Cell Tumour affecting the proximal end of femur is presented. Following a wide excision, the hip was reconstructed using Charnley type of low friction total hip arthroplasty. At a 32 month review, there was no recurrence and the function was good.

  12. Cerebellar abiotrophy in a miniature schnauzer

    OpenAIRE

    Berry, Michelle L.; Blas-Machado, Uriel

    2003-01-01

    A 3.5-month-old miniature schnauzer was presented for signs of progressive cerebellar ataxia. Necropsy revealed cerebellar abiotrophy. This is the first reported case of cerebellar abiotrophy in a purebred miniature schnauzer.

  13. Cerebellar abiotrophy in a miniature schnauzer.

    Science.gov (United States)

    Berry, Michelle L; Blas-Machado, Uriel

    2003-08-01

    A 3.5-month-old miniature schnauzer was presented for signs of progressive cerebellar ataxia. Necropsy revealed cerebellar abiotrophy. This is the first reported case of cerebellar abiotrophy in a purebred miniature schnauzer.

  14. A miniaturized electrochemical toxicity biosensor based on graphene oxide quantum dots/carboxylated carbon nanotubes for assessment of priority pollutants

    Energy Technology Data Exchange (ETDEWEB)

    Zhu, Xiaolin; Wu, Guanlan; Lu, Nan [School of Environment, Northeast Normal University, Changchun 130117 (China); Yuan, Xing, E-mail: yuanx@nenu.edu.cn [School of Environment, Northeast Normal University, Changchun 130117 (China); Li, Baikun, E-mail: baikun@engr.uconn.edu [Department of Civil and Environmental Engineering, University of Connecticut, Storrs, CT 06269 (United States)

    2017-02-15

    Highlights: • Graphene oxide quantum dots/carboxylated carbon nanotubes hybrid was developed. • The cytotoxicity detection vessel was miniaturized to the 96-well plate. • The electrochemical behavior of HepG2 cell was investigated for the first time. • The mixture signal of adenine and hypoxanthine was separated successfully. • The biosensor was used to assess the toxicity of heavy metals and phenols. - Abstract: The study presented a sensitive and miniaturized cell-based electrochemical biosensor to assess the toxicity of priority pollutants in the aquatic environment. Human hepatoma (HepG2) cells were used as the biological recognition agent to measure the changes of electrochemical signals and reflect the cell viability. The graphene oxide quantum dots/carboxylated carbon nanotubes hybrid was developed in a facile and green way. Based on the hybrid composite modified pencil graphite electrode, the cell culture and detection vessel was miniaturized to a 96-well plate instead of the traditional culture dish. In addition, three sensitive electrochemical signals attributed to guanine/xanthine, adenine, and hypoxanthine were detected simultaneously. The biosensor was used to evaluate the toxicity of six priority pollutants, including Cd, Hg, Pb, 2,4-dinitrophenol, 2,4,6-trichlorophenol, and pentachlorophenol. The 24 h IC{sub 50} values obtained by the electrochemical biosensor were lower than those of conventional MTT assay, suggesting the enhanced sensitivity of the electrochemical assay towards heavy metals and phenols. This platform enables the label-free and sensitive detection of cell physiological status with multi-parameters and constitutes a promising approach for toxicity detection of pollutants. It makes possible for automatical and high-throughput analysis on nucleotide catabolism, which may be critical for life science and toxicology.

  15. Complications of resection and reconstruction in giant cell tumour of distal end of radius - An analysis

    Directory of Open Access Journals (Sweden)

    Saraf S

    2005-01-01

    Full Text Available Background: The bulk of literature on the subject focuses on the resection of the tumor followed by reconstruction using autologous fibula, however, papers analyzing the failures of this procedure are scanty. The aim is to analyze the various factors responsible for the failures. Methods: Study included 42 patients of aggressive GCT of distal radius, resected and reconstructed using nonvascularised autologous fibula. Host graft junction was fixed using screws (6, intramedullary nail (21 and plate (15. The minimum follow-up was 2 years or till a complication occurred requiring second surgery. Result: The major complications were recurrence in 6 cases (spillage of tumor tissue in 3, poor biopsy site 2, recurrence along the nail tract one case; failure of host graft union in 8 cases due to inadequate contact at host graft junction, poor implant selection, inadequate immobilization and infection; significant instability at wrist in 6 cases due to poor stabilization at carpo fibular junction in addition to inherent instability due to poor congruity between fibulocarpal articulations. Conclusion: Reconstruction of distal end of radius using auto fibula has much higher complication rates than usually believed. A meticulous planning and its execution is must to minimize the problems. Use of dynamic plate for host graft junction and fixation of fibular head to adjacent ulna/carpal bones improves the results.

  16. Drilling miniature holes, Part III

    Energy Technology Data Exchange (ETDEWEB)

    Gillespie, L.K.

    1978-07-01

    Miniature components for precision electromechanical mechanisms such as switches, timers, and actuators typically require a number of small holes. Because of the precision required, the workpiece materials, and the geometry of the parts, most of these holes must be produced by conventional drilling techniques. The use of such techniques is tedious and often requires considerable trial and error to prevent drill breakage, minimize hole mislocation and variations in hole diameter. This study of eight commercial drill designs revealed that printed circuit board drills produced better locational and size repeatability than did other drills when centerdrilling was not used. Boring holes 1 mm in dia, or less, as a general rule did not improve hole location in brass or stainless steel. Hole locations of patterns of 0.66-mm holes can be maintained within 25.4-..mu..m diametral positional tolerance if setup misalignments can be eliminated. Size tolerances of +- 3.8 ..mu..m can be maintained under some conditions when drilling flat plates. While these levels of precision are possible with existing off-the-shelf drills, they may not be practical in many cases.

  17. Pretinning Nickel-Plated Wire Shields

    Science.gov (United States)

    Igawa, J. A.

    1985-01-01

    Nickel-plated copper shielding for wires pretinned for subsequent soldering with help of activated rosin flux. Shield cut at point 0.25 to 0.375 in. (6 to 10 mm) from cut end of outer jacket. Loosened end of shield straightened and pulled toward cut end. Insulation of inner wires kept intact during pretinning.

  18. Design and Fabrication of a Miniaturized GMI Magnetic Sensor Based on Amorphous Wire by MEMS Technology

    Directory of Open Access Journals (Sweden)

    Jiawen Chen

    2018-03-01

    Full Text Available A miniaturized Co-based amorphous wire GMI (Giant magneto-impedance magnetic sensor was designed and fabricated in this paper. The Co-based amorphous wire was used as the sense element due to its high sensitivity to the magnetic field. A three-dimensional micro coil surrounding the Co-based amorphous wire was fabricated by MEMS (Micro-Electro-Mechanical System technology, which was used to extract the electrical signal. The three-dimensional micro pick-up coil was designed and simulated with HFSS (High Frequency Structure Simulator software to determine the key parameters. Surface micro machining MEMS (Micro-Electro-Mechanical System technology was employed to fabricate the three-dimensional coil. The size of the developed amorphous wire magnetic sensor is 5.6 × 1.5 × 1.1 mm3. Helmholtz coil was used to characterize the performance of the device. The test results of the sensor sample show that the voltage change is 130 mV/Oe and the linearity error is 4.83% in the range of 0~45,000 nT. The results indicate that the developed miniaturized magnetic sensor has high sensitivity. By testing the electrical resistance of the samples, the results also showed high uniformity of each device.

  19. Inheritance of congenital cataracts and microphthalmia in the Miniature Schnauzer.

    Science.gov (United States)

    Gelatt, K N; Samuelson, D A; Bauer, J E; Das, N D; Wolf, E D; Barrie, K P; Andresen, T L

    1983-06-01

    Congenital cataracts and microphthalmia in the Miniature Schnauzer were inherited as an autosomal recessive trait. Eighteen matings of affected X affected Miniature Schnauzers resulted in 87 offspring with congenital cataracts and microphthalmia (49 males/38 females). Two matings of congenital cataractous and microphthalmic Miniature Schnauzers (2 females) X a normal Miniature Schnauzer (1 male) yielded 11 clinically normal Miniature Schnauzers (7 males/4 females). Eighteen matings of congenital cataractous and microphthalmic Miniature Schnauzers (6 males) X carrier Miniature Schnauzers (9 females) produced 81 offspring; 39 exhibited congenital cataracts and microphthalmia (20 males/19 females) and 42 had clinically normal eyes (17 males/25 females).

  20. Giant grains

    International Nuclear Information System (INIS)

    Leitch-Devlin, M.A.; Millar, T.J.; Williams, D.A.

    1976-01-01

    Infrared observations of the Orion nebula have been interpreted by Rowan-Robinson (1975) to imply the existence of 'giant' grains, radius approximately 10 -2 cm, throughout a volume about a parsec in diameter. Although Rowan-Robinson's model of the nebula has been criticized and the presence of such grains in Orion is disputed, the proposition is accepted, that they exist, and in this paper situations in which giant grains could arise are examined. It is found that, while a giant-grain component to the interstellar grain density may exist, it is difficult to understand how giant grains arise to the extent apparently required by the Orion nebula model. (Auth.)

  1. Miniature interferometer for refractive index measurement in microfluidic chip

    Science.gov (United States)

    Chen, Minghui; Geiser, Martial; Truffer, Frederic; Song, Chengli

    2012-12-01

    The design and development of the miniaturized interferometer for measurement of the refractive index or concentration of sub-microliter volume aqueous solution in microfludic chip is presented. It is manifested by a successful measurement of the refractive index of sugar-water solution, by utilizing a laser diode for light source and the small robust instrumentation for practical implementation. Theoretically, the measurement principle and the feasibility of the system are analyzed. Experimental device is constructed with a diode laser, lens, two optical plate and a complementary metal oxide semiconductor (CMOS). Through measuring the positional changes of the interference fringes, the refractive index change are retrieved. A refractive index change of 10-4 is inferred from the measured image data. The entire system is approximately the size of half and a deck of cards and can operate on battery power for long time.

  2. Serum C-reactive protein concentrations in healthy Miniature Schnauzer dogs.

    Science.gov (United States)

    Wong, Valerie M; Kidney, Beverly A; Snead, Elisabeth C R; Myers, Sherry L; Jackson, Marion L

    2011-09-01

    C-reactive protein (CRP) is a sensitive marker for inflammation in people and dogs. In people, an association between CRP concentration and atherosclerosis has been reported. Atherosclerosis is rare in dogs, but the Miniature Schnauzer breed may be at increased risk for developing this vascular disease. It is not known if CRP concentrations in Miniature Schnauzer dogs differ from those in other dog breeds. Our objectives were to validate an automated human CRP assay for measuring CRP in dogs and compare CRP concentrations in healthy Miniature Schnauzer dogs with those in non-Miniature Schnauzer breeds. Sera from 37 non-Miniature Schnauzer dogs with inflammatory disease were pooled and used to validate a human CRP immunoturbidimetric assay for measuring canine CRP. Blood was collected from 20 healthy Miniature Schnauzer dogs and 41 healthy dogs of other breeds. Median serum CRP concentration of healthy Miniature Schnauzer dogs was compared with that of healthy non-Miniature Schnauzer dogs. The human CRP assay measured CRP reliably with linearity between 0 and 20 mg/L. CRP concentration for healthy Miniature Schnauzer dogs (median 4.0 mg/L, minimum-maximum 0-18.2 mg/L) was significantly higher than for the healthy non-Miniature Schnauzer dogs (median 0.1 mg/L, minimum-maximum 0-10.7 mg/L); 17 of the 20 Miniature Schnauzer dogs had values that overlapped with those of the non-Miniature Schnauzer dogs. Median CRP concentration of Miniature Schnauzer dogs was slightly higher than that of other breeds of dogs. A relationship between higher CRP concentration in Miniature Schnauzer dogs and idiopathic hyperlipidemia, pancreatitis, and possible increased risk for atherosclerosis remains to be determined. ©2011 American Society for Veterinary Clinical Pathology.

  3. Miniature transposable sequences are frequently mobilized in the bacterial plant pathogen Pseudomonas syringae pv. phaseolicola.

    Directory of Open Access Journals (Sweden)

    Leire Bardaji

    Full Text Available Mobile genetic elements are widespread in Pseudomonas syringae, and often associate with virulence genes. Genome reannotation of the model bean pathogen P. syringae pv. phaseolicola 1448A identified seventeen types of insertion sequences and two miniature inverted-repeat transposable elements (MITEs with a biased distribution, representing 2.8% of the chromosome, 25.8% of the 132-kb virulence plasmid and 2.7% of the 52-kb plasmid. Employing an entrapment vector containing sacB, we estimated that transposition frequency oscillated between 2.6×10(-5 and 1.1×10(-6, depending on the clone, although it was stable for each clone after consecutive transfers in culture media. Transposition frequency was similar for bacteria grown in rich or minimal media, and from cells recovered from compatible and incompatible plant hosts, indicating that growth conditions do not influence transposition in strain 1448A. Most of the entrapped insertions contained a full-length IS801 element, with the remaining insertions corresponding to sequences smaller than any transposable element identified in strain 1448A, and collectively identified as miniature sequences. From these, fragments of 229, 360 and 679-nt of the right end of IS801 ended in a consensus tetranucleotide and likely resulted from one-ended transposition of IS801. An average 0.7% of the insertions analyzed consisted of IS801 carrying a fragment of variable size from gene PSPPH_0008/PSPPH_0017, showing that IS801 can mobilize DNA in vivo. Retrospective analysis of complete plasmids and genomes of P. syringae suggests, however, that most fragments of IS801 are likely the result of reorganizations rather than one-ended transpositions, and that this element might preferentially contribute to genome flexibility by generating homologous regions of recombination. A further miniature sequence previously found to affect host range specificity and virulence, designated MITEPsy1 (100-nt, represented an average 2

  4. Miniature transposable sequences are frequently mobilized in the bacterial plant pathogen Pseudomonas syringae pv. phaseolicola.

    Science.gov (United States)

    Bardaji, Leire; Añorga, Maite; Jackson, Robert W; Martínez-Bilbao, Alejandro; Yanguas-Casás, Natalia; Murillo, Jesús

    2011-01-01

    Mobile genetic elements are widespread in Pseudomonas syringae, and often associate with virulence genes. Genome reannotation of the model bean pathogen P. syringae pv. phaseolicola 1448A identified seventeen types of insertion sequences and two miniature inverted-repeat transposable elements (MITEs) with a biased distribution, representing 2.8% of the chromosome, 25.8% of the 132-kb virulence plasmid and 2.7% of the 52-kb plasmid. Employing an entrapment vector containing sacB, we estimated that transposition frequency oscillated between 2.6×10(-5) and 1.1×10(-6), depending on the clone, although it was stable for each clone after consecutive transfers in culture media. Transposition frequency was similar for bacteria grown in rich or minimal media, and from cells recovered from compatible and incompatible plant hosts, indicating that growth conditions do not influence transposition in strain 1448A. Most of the entrapped insertions contained a full-length IS801 element, with the remaining insertions corresponding to sequences smaller than any transposable element identified in strain 1448A, and collectively identified as miniature sequences. From these, fragments of 229, 360 and 679-nt of the right end of IS801 ended in a consensus tetranucleotide and likely resulted from one-ended transposition of IS801. An average 0.7% of the insertions analyzed consisted of IS801 carrying a fragment of variable size from gene PSPPH_0008/PSPPH_0017, showing that IS801 can mobilize DNA in vivo. Retrospective analysis of complete plasmids and genomes of P. syringae suggests, however, that most fragments of IS801 are likely the result of reorganizations rather than one-ended transpositions, and that this element might preferentially contribute to genome flexibility by generating homologous regions of recombination. A further miniature sequence previously found to affect host range specificity and virulence, designated MITEPsy1 (100-nt), represented an average 2.4% of the total

  5. Phosphorus-31 NMR (nuclear magnetic resonance) analysis of gold plating baths

    Energy Technology Data Exchange (ETDEWEB)

    Smith, R.E.

    1990-01-01

    This report describes the nuclear magnetic resonance (NMR) analysis of the gold plating baths in the Micro-Miniature Electronic Assembly department of Allied-Signal Inc., Kansas City Division (KCD). The baths were analyzed for phosphorylated components. In freshly prepared gold plating baths, a 50-percent aqueous solution of aminotrimethylphosphonate (ATMP) is the principal compound observed. As the bath is used in production, the ATMP breaks down and new materials (phosphate, ADMP, and AMMP) are identified. The NMR method was used to monitor the concentrations of the ATMP and breakdown products for a nine-month period. The 225-liter bath had plated approximately 100 square feet of gold during the nine-month period. These results can be used to predict the performance of baths as they are used in production. The accuracy of the analysis is 96 percent for ATMP and 92 percent for phosphate. The precision (relative standard deviation) is 5.2 percent for ATMP and 4.5 percent for phosphate. 1 ref., 5 figs., 2 tabs.

  6. Giant-Cell Tumor of the Distal Ulna Treated by Wide Resection and Ulnar Support Reconstruction: A Case Report

    Directory of Open Access Journals (Sweden)

    Akio Minami

    2010-01-01

    Full Text Available Giant-cell tumor of bone occurred in the distal end of the ulna is extremely uncommon. A 23-year-old male had a giant-cell tumor occurred in the distal end of the ulna. After wide resection of the distal segment of the ulna including giant-cell tumor, ulnar components of the wrist joint were reconstructed with modified Sauvé-Kapandji procedure using the iliac bone graft, preserving the triangular fibrocartilage complex and ulnar collateral ligament in order to maintain ulnar support of the wrist, and the proximal stump of the resected ulna was stabilized by tenodesis using the extensor carpi ulnaris tendon. One year after operation, the patient's wrist was pain-free and had a full range of motion. Postoperative X-rays showed no abnormal findings including recurrence of the giant-cell tumor and ulnar translation of the entire carpus. The stability of the proximal stump of the distal ulna was also maintained.

  7. Techniques in the management of juxta-articular aggressive and recurrent giant cell tumors around the knee.

    Science.gov (United States)

    Vidyadhara, S; Rao, S K

    2007-03-01

    Juxta-articular aggressive and recurrent giant cell tumors around the knee pose difficulties in management. This article reviews current problems and options in the management of these giant cell tumors. A systematic search was performed on juxta-articular aggressive and recurrent giant cell tumor. Additional information was retrieved from hand searching the literature and from relevant congress proceedings. We addressed the following issues: general consensus on early diagnosis and techniques in its management. In particular, we describe our results with resection arthrodesis performed combining the benefits of both interlocking intramedullary nail and Ilizarov fixator in the management of these tumors around the knee. Mean operative age of the 22 patients undergoing resection arthrodesis was 35.63 years. Seven lesions were in the tibia and fifteen in the femur. Mean length of the bone defect was 12.34 cm. The mean external fixator index was 7.44 days/cm and the distraction index was 7.88 days/cm. Mean period of follow-up for the patients was 64.5 months. The function of the affected limb was rated excellent in 10 and good and fair in six patients each as per Enneking criteria. No local recurrence of tumor was seen. Seven complications occurred in five patients. Two-ring construct, bifocal bone transport, and early definite plate osteosynthesis with additional bone grafting of the docking site at the end of distraction even before consolidation of the regenerate helps to reduce the problems of pin tract infections drastically. Thin-diameter long intramedullary nail in addition to preserving the endosteal blood supply also prevents mal-alignment of the regenerate. Thus resection arthrodesis using interlocking intramedullary nail and bone transport using Ilizarov fixator is cost effective and effective in achieving the desired goals of reconstruction with least complications in selected patients with specific indications.

  8. Structural factors controlling inter-plate coupling and earthquake rupture process

    Science.gov (United States)

    Kodaira, S.

    2007-05-01

    Recent availability of a large number of ocean bottom seismographs (OBSs), a large volume of air-gun array and a long streamer cable for academics provide several new findings of lithospheric scale structures in subduction seismogenic zones. JAMSTEC has acquired long-offset seismic data using a super-densely deploy OBS (i.e. 1 - 5 km spacing OBSs along 100 - 500 km long profiles) in the Nankai seismogeinc zone, SW. Japan, since 1999. Long-offset multichannel seismic (MCS) data by a two-ship experiment, as well as conventional 2D MCS data, have been also acquired at a part of the profiles. Some of those profiles have been designed as combined onshore - offshore profiles for imaging a land-ocean transition zone. One of the most striking findings is an image of several scales of subducted seamounts/ridges in the Nankai trough seismogenic zone. We detected the subducted seamount/ridges, which are 50 - 100 km wide, distributing from near trough axis to ~ 40 km deep beneath the Japanese island. From a point of seismogenic process, an important aspect is that those structures are strongly correlated with slip zones of magnitude 8-class earthquakes, i.e.; subducted seamounts/ridge control the rupture propagations. Moreover, the most recent seismic study crossing the segmentation boundary between M=8 class earthquakes detected a high seismic velocity body forming a strongly coupled patch at the segmentation boundary. The numerical simulation incorporating all those structures explained the historic rupture patterns, and shows the occurrence of a giant earthquake along the entire Nankai trough, a distance of over 600 km long (Mw=8.7). The growth processes of a rupture revealed from the simulation are; 1) prior to the giant earthquake, a small slow event (or earthquake) occurs near the segmentation boundary, 2) this accelerates a very slow slip (slower than the plate convergent rate), at the strong patch, which reduces a degree of coupling, 3) then a rupture easily propagates

  9. Magma Reservoirs Feeding Giant Radiating Dike Swarms: Insights from Venus

    Science.gov (United States)

    Grosfils, E. B.; Ernst, R. E.

    2003-01-01

    Evidence of lateral dike propagation from shallow magma reservoirs is quite common on the terrestrial planets, and examination of the giant radiating dike swarm population on Venus continues to provide new insight into the way these complex magmatic systems form and evolve. For example, it is becoming clear that many swarms are an amalgamation of multiple discrete phases of dike intrusion. This is not surprising in and of itself, as on Earth there is clear evidence that formation of both magma reservoirs and individual giant radiating dikes often involves periodic magma injection. Similarly, giant radiating swarms on Earth can contain temporally discrete subswarms defined on the basis of geometry, crosscutting relationships, and geochemical or paleomagnetic signatures. The Venus data are important, however, because erosion, sedimentation, plate tectonic disruption, etc. on Earth have destroyed most giant radiating dike swarm's source regions, and thus we remain uncertain about the geometry and temporal evolution of the magma sources from which the dikes are fed. Are the reservoirs which feed the dikes large or small, and what are the implications for how the dikes themselves form? Does each subswarm originate from a single, periodically reactivated reservoir, or do subswarms emerge from multiple discrete geographic foci? If the latter, are these discrete foci located at the margins of a single large magma body, or do multiple smaller reservoirs define the character of the magmatic center as a whole? Similarly, does the locus of magmatic activity change with time, or are all the foci active simultaneously? Careful study of giant radiating dike swarms on Venus is yielding the data necessary to address these questions and constrain future modeling efforts. Here, using giant radiating dike swarms from the Nemesis Tessera (V14) and Carson (V43) quadrangles as examples, we illustrate some of the dike swarm focal region diversity observed on Venus and briefly explore some

  10. GIANT CELL-RICH LESIONS OF BONE AND JOINTS: A ONE YEAR PROSPECTIVE STUDY

    Directory of Open Access Journals (Sweden)

    Sri Nithisa H

    2016-07-01

    Full Text Available BACKGROUND Giant cell-rich lesions constitute a group of biologically and morphologically diverse bone and joint tumours. The common feature is presence of numerous multinucleated osteoclast-like giant cells. However, they differ from each other by in terms of clinical and radiographic features and in many cases by their distinct morphological features. METHODS All the bone and joint specimens with giant cell-rich lesions received in the period of one year were studied along with clinical and radiological data available. Gross and microscopic findings were noted. RESULTS In a period of one year, 10 cases of giant cell-rich lesions of bone and joints have been studied, which were and correlated with clinical and radiological findings. Five were lesions from bone and two were from joints, which are chondroblastoma, chondromyxoid fibroma, osteoclastoma, aneurysmal bone cyst, pigmented villonodular synovitis, giant cell lesion of tendon sheath, and tendinous xanthoma. CONCLUSION In the present study, variety of giant cell lesions of bone and joints are studied. Of which, the mean age in young patients being 20 years and in elderly patients being 50 years. The common site being lower end of femur.

  11. Fuel cell cooler-humidifier plate

    Science.gov (United States)

    Vitale, Nicholas G.; Jones, Daniel O.

    2000-01-01

    A cooler-humidifier plate for use in a proton exchange membrane (PEM) fuel cell stack assembly is provided. The cooler-humidifier plate combines functions of cooling and humidification within the fuel cell stack assembly, thereby providing a more compact structure, simpler manifolding, and reduced reject heat from the fuel cell. Coolant on the cooler side of the plate removes heat generated within the fuel cell assembly. Heat is also removed by the humidifier side of the plate for use in evaporating the humidification water. On the humidifier side of the plate, evaporating water humidifies reactant gas flowing over a moistened wick. After exiting the humidifier side of the plate, humidified reactant gas provides needed moisture to the proton exchange membranes used in the fuel cell stack assembly. The invention also provides a fuel cell plate that maximizes structural support within the fuel cell by ensuring that the ribs that form the boundaries of channels on one side of the plate have ends at locations that substantially correspond to the locations of ribs on the opposite side of the plate.

  12. Allometry indicates giant eyes of giant squid are not exceptional.

    Science.gov (United States)

    Schmitz, Lars; Motani, Ryosuke; Oufiero, Christopher E; Martin, Christopher H; McGee, Matthew D; Gamarra, Ashlee R; Lee, Johanna J; Wainwright, Peter C

    2013-02-18

    The eyes of giant and colossal squid are among the largest eyes in the history of life. It was recently proposed that sperm whale predation is the main driver of eye size evolution in giant squid, on the basis of an optical model that suggested optimal performance in detecting large luminous visual targets such as whales in the deep sea. However, it is poorly understood how the eye size of giant and colossal squid compares to that of other aquatic organisms when scaling effects are considered. We performed a large-scale comparative study that included 87 squid species and 237 species of acanthomorph fish. While squid have larger eyes than most acanthomorphs, a comparison of relative eye size among squid suggests that giant and colossal squid do not have unusually large eyes. After revising constants used in a previous model we found that large eyes perform equally well in detecting point targets and large luminous targets in the deep sea. The eyes of giant and colossal squid do not appear exceptionally large when allometric effects are considered. It is probable that the giant eyes of giant squid result from a phylogenetically conserved developmental pattern manifested in very large animals. Whatever the cause of large eyes, they appear to have several advantages for vision in the reduced light of the deep mesopelagic zone.

  13. Giant panda foraging and movement patterns in response to bamboo shoot growth.

    Science.gov (United States)

    Zhang, Mingchun; Zhang, Zhizhong; Li, Zhong; Hong, Mingsheng; Zhou, Xiaoping; Zhou, Shiqiang; Zhang, Jindong; Hull, Vanessa; Huang, Jinyan; Zhang, Hemin

    2018-03-01

    Diet plays a pivotal role in dictating behavioral patterns of herbivorous animals, particularly specialist species. The giant panda (Ailuropoda melanoleuca) is well-known as a bamboo specialist. In the present study, the response of giant pandas to spatiotemporal variation of bamboo shoots was explored using field surveys and GPS collar tracking. Results show the dynamics in panda-bamboo space-time relationships that have not been previously articulated. For instance, we found a higher bamboo stump height of foraged bamboo with increasing elevation, places where pandas foraged later in spring when bamboo shoots become more fibrous and woody. The time required for shoots to reach optimum height for foraging was significantly delayed as elevation increased, a pattern which corresponded with panda elevational migration patterns beginning from the lower elevational end of Fargesia robusta distribution and gradually shifting upward until the end of the shooting season. These results indicate that giant pandas can respond to spatiotemporal variation of bamboo resources, such as available shoots. Anthropogenic interference of low-elevation F. robusta habitat should be mitigated, and conservation attention and increased monitoring should be given to F. robusta areas at the low- and mid-elevation ranges, particularly in the spring shooting season.

  14. Giant Cell Tumour of the Distal Ulna: A Rare Presentation

    Directory of Open Access Journals (Sweden)

    Ruben Jaya Kumar

    2011-07-01

    Full Text Available Giant-cell tumour (GCT of bone, a primary yet locally aggressive benign tumour, commonly affects patients between the ages of 20 and 40 years, with the peak incidence occurring in the third decade. Women are affected slightly more than men. The distal end of the ulna is an extremely uncommon site for primary bone tumours in general and giant cell tumours in particular. Wide resection of the distal ulna is the recommended treatment for GCT in such locations. Radio-ulna convergence and dorsal displacement of the ulna stump are known complications following ulna resection proximal to the insertion of the pronator quadratus. This leads to reduction in grip power and forearm rotatory motion. Stabilization of the ulna stump with extensor carpi ulnaris (ECU tendon after wide resection of the tumour has been described in the literature. We report a case of GCT of distal end of ulna treated with wide resection and stabilization with ECU tendon.

  15. Reestablishment of radiographic kidney size in Miniature Schnauzer dogs.

    Science.gov (United States)

    Sohn, Jungmin; Yun, Sookyung; Lee, Jeosoon; Chang, Dongwoo; Choi, Mincheol; Yoon, Junghee

    2017-01-10

    Kidney size may be altered in renal diseases, and the detection of kidney size alteration has diagnostic and prognostic values. We hypothesized that radiographic kidney size, the kidney length to the second lumbar vertebra (L2) length ratio, in normal Miniature Schnauzer dogs may be overestimated due to their shorter vertebral length. This study was conducted to evaluate radiographic and ultrasonographic kidney size and L2 length in clinically normal Miniature Schnauzers and other dog breeds to evaluate the effect of vertebral length on radiographic kidney size and to reestablish radiographic kidney size in normal Miniature Schnauzers. Abdominal radiographs and ultrasonograms from 49 Miniature Schnauzers and 54 other breeds without clinical evidence of renal disease and lumbar vertebral abnormality were retrospectively evaluated. Radiographic kidney size, in the Miniature Schnauzer (3.31 ± 0.26) was significantly larger than that in other breeds (2.94 ± 0.27). Relative L2 length, the L2 length to width ratio, in the Miniature Schnauzer (1.11 ± 0.06) was significantly shorter than that in other breeds (1.21 ± 0.09). However, ultrasonographic kidney sizes, kidney length to aorta diameter ratios, were within or very close to normal range both in the Miniature Schnauzer (6.75 ± 0.67) and other breeds (7.16 ± 1.01). Thus, Miniature Schnauzer dogs have breed-specific short vertebrae and consequently a larger radiographic kidney size, which was greater than standard reference in normal adult dogs. Care should be taken when evaluating radiographic kidney size in Miniature Schnauzers to prevent falsely diagnosed renomegaly.

  16. Small Scaffolds, Big Potential: Developing Miniature Proteins as Therapeutic Agents.

    Science.gov (United States)

    Holub, Justin M

    2017-09-01

    Preclinical Research Miniature proteins are a class of oligopeptide characterized by their short sequence lengths and ability to adopt well-folded, three-dimensional structures. Because of their biomimetic nature and synthetic tractability, miniature proteins have been used to study a range of biochemical processes including fast protein folding, signal transduction, catalysis and molecular transport. Recently, miniature proteins have been gaining traction as potential therapeutic agents because their small size and ability to fold into defined tertiary structures facilitates their development as protein-based drugs. This research overview discusses emerging developments involving the use of miniature proteins as scaffolds to design novel therapeutics for the treatment and study of human disease. Specifically, this review will explore strategies to: (i) stabilize miniature protein tertiary structure; (ii) optimize biomolecular recognition by grafting functional epitopes onto miniature protein scaffolds; and (iii) enhance cytosolic delivery of miniature proteins through the use of cationic motifs that facilitate endosomal escape. These objectives are discussed not only to address challenges in developing effective miniature protein-based drugs, but also to highlight the tremendous potential miniature proteins hold for combating and understanding human disease. Drug Dev Res 78 : 268-282, 2017. © 2017 Wiley Periodicals, Inc. © 2017 Wiley Periodicals, Inc.

  17. Miniaturized isothermal nucleic acid amplification, a review.

    Science.gov (United States)

    Asiello, Peter J; Baeumner, Antje J

    2011-04-21

    Micro-Total Analysis Systems (µTAS) for use in on-site rapid detection of DNA or RNA are increasingly being developed. Here, amplification of the target sequence is key to increasing sensitivity, enabling single-cell and few-copy nucleic acid detection. The several advantages to miniaturizing amplification reactions and coupling them with sample preparation and detection on the same chip are well known and include fewer manual steps, preventing contamination, and significantly reducing the volume of expensive reagents. To-date, the majority of miniaturized systems for nucleic acid analysis have used the polymerase chain reaction (PCR) for amplification and those systems are covered in previous reviews. This review provides a thorough overview of miniaturized analysis systems using alternatives to PCR, specifically isothermal amplification reactions. With no need for thermal cycling, isothermal microsystems can be designed to be simple and low-energy consuming and therefore may outperform PCR in portable, battery-operated detection systems in the future. The main isothermal methods as miniaturized systems reviewed here include nucleic acid sequence-based amplification (NASBA), loop-mediated isothermal amplification (LAMP), helicase-dependent amplification (HDA), rolling circle amplification (RCA), and strand displacement amplification (SDA). Also, important design criteria for the miniaturized devices are discussed. Finally, the potential of miniaturization of some new isothermal methods such as the exponential amplification reaction (EXPAR), isothermal and chimeric primer-initiated amplification of nucleic acids (ICANs), signal-mediated amplification of RNA technology (SMART) and others is presented.

  18. Giant cell tumor of bone: Multimodal approach

    Directory of Open Access Journals (Sweden)

    Gupta A

    2007-01-01

    Full Text Available Background: The clinical behavior and treatment of giant cell tumor of bone is still perplexing. The aim of this study is to clarify the clinico-pathological correlation of tumor and its relevance in treatment and prognosis. Materials and Methods: Ninety -three cases of giant cell tumor were treated during 1980-1990 by different methods. The age of the patients varied from 18-58 yrs with male and female ratio as 5:4. The upper end of the tibia was most commonly involved (n=31, followed by the lower end of the femur(n=21, distal end of radius(n=14,upper end of fibula (n=9,proximal end of femur(n=5, upper end of the humerus(n=3, iliac bone(n=2,phalanx (n=2 and spine(n=1. The tumors were also encountered on uncommon sites like metacarpals (n=4 and metatarsal(n=1. Fifty four cases were treated by curettage and bone grafting. Wide excision and reconstruction was performed in twenty two cases . Nine cases were treated by wide excision while primary amputation was performed in four cases. One case required only curettage. Three inaccessible lesions of ilium and spine were treated by radiotherapy. Results: 19 of 54 treated by curettage and bone grafting showed a recurrence. The repeat curettage and bone grafting was performed in 18 cases while amputation was done in one. One each out of the cases treated by wide excision and reconstruction and wide excision alone recurred. In this study we observed that though curettage and bone grafting is still the most commonly adopted treatment, wide excision of tumor with reconstruction has shown lesser recurrence. Conclusion: For radiologically well-contained and histologically typical tumor, curettage and autogenous bone grafting is the treatment of choice . The typical tumors with radiologically deficient cortex, clinically aggressive tumors and tumors with histological Grade III should be treated by wide excision and reconstruction.

  19. Thermal Behaviour of Beams with Slant End-Plate Connection Subjected to Nonsymmetric Gravity Load

    Directory of Open Access Journals (Sweden)

    Farshad Zahmatkesh

    2014-01-01

    Full Text Available Research on the steel structures with confining of axial expansion in fixed beams has been quite intensive in the past decade. It is well established that the thermal behaviour has a key influence on steel structural behaviours. This paper describes mechanical behaviour of beams with bolted slant end-plate connection with nonsymmetric gravity load, subjected to temperature increase. Furthermore, the performance of slant connections of beams in steel moment frame structures in the elastic field is investigated. The proposed model proved that this flexible connection system could successfully decrease the extra thermal induced axial force by both of the friction force dissipation among two faces of slant connection and a small upward movement on the slant plane. The applicability of primary assumption is illustrated. The results from the proposed model are examined within various slant angles, thermal and friction factors. It can be concluded that higher thermal conditions are tolerable when slanting connection is used.

  20. Coupling intensity and isostatic competition between subducting slab and overriding plate control trench motions and tectonics of the overriding plate

    Science.gov (United States)

    Wu, G.; Moresi, L. N.

    2017-12-01

    Trench motions not only reflect tectonic regimes on the overriding plate but also shed light on the competition between subducting slab and overriding plate, however, major controls over trench advance or retreat and their consequences are still illusive. We use 2D thermo-mechanical experiments to study the problem. We find that the coupling intensity particularly in the uppermost 200 km and the isostatic competition between subducting slab and overriding plate largely determine trench motion and tectonics of in the overriding plate. Coupling intensity is the result of many contributing factors, including frictional coefficient of brittle part of the subducting interface and the viscosity of the ductile part, thermal regime and rheology of the overriding plate, and water contents and magmatic activity in the subducting slab and overriding plate. In this study, we are not concerned with the dynamic evolution of individual controlling parameter but simply use effective media. For instance, we impose simple model parameters such as frictional coefficient and vary the temperature and strain-rate dependent viscosity of the weak layer between the subducting slab and overriding plate. In the coupled end-member case, strong coupling leads to strong corner flow, depth-dependent compression/extension, and mantle return flow on the overriding plate side. It results in fast trench retreat, broad overriding plate extension, and even slab breakoff. In the decoupled end-member case, weak coupling causes much weaker response on the overriding plate side compared with the coupled end-member case, and the subducting slab can be largely viewed as a conveyer belt. We find that the isostatic competition between the subducting slab and overriding plate also has a major control over trench motion, and may better be viewed in 3D models. This is consistent with the findings in previous 3D studies that trench motion is most pronounced close to the slab edge. Here we propose that the

  1. Liquid storage of miniature boar semen.

    Science.gov (United States)

    Shimatsu, Yoshiki; Uchida, Masaki; Niki, Rikio; Imai, Hiroshi

    2002-04-01

    The effects of liquid storage at 15 degrees C on the fertilizing ability of miniature pig semen were investigated. Characterization of ejaculated semen from 3 miniature boars was carried out. Semen volume and pH were similar among these boars. In one of the boars, sperm motility was slightly low, and sperm concentration and total number of sperm were significantly lower than in the others (P semen was substituted with various extenders (Kiev, Androhep, BTS and Modena) by centrifugation and semen was stored for 7 days at 15 degrees C. Sperm motility was estimated daily at 37 degrees C. For complete substitution of seminal plasma, Modena was significantly more efficient than the other extenders (P Semen from each of the 3 miniature boars that had been stored for 5 to 7 days at 15 degrees C in Modena was used for artificial insemination of 15 miniature sows. The farrowing rates were 100, 100 and 60%, and litter sizes were 6.4 +/- 1.5, 5.8 +/- 0.8 and 5.0 +/- 1.0 for each boar semen, respectively. The boar that sired the smallest farrowing rate was the same one that showed lower seminal quality with respect to sperm motility, sperm concentration and total number of sperm. These results suggest that miniature boar semen can be stored for at least 5 days at 15 degrees C by the substitution of seminal plasma with Modena extender.

  2. Laser weld reconstitution of conventional Charpy and Miniaturized Notch Test (MNT) specimens

    International Nuclear Information System (INIS)

    Manahan, M.P.; Williams, J.; Martukanitz, R.P.

    1993-01-01

    As nuclear power plants approach end-of-license (EOL) and consideration is given to license renewal, there is an ever increasing need to expand the amount of data obtainable from the original surveillance specimens. A laser welding technique to reconstitute broken Charpy specimens is being developed to produce both conventional and miniaturized Charpy specimens. This paper reports on early laser welding development efforts and summarizes previous proof-of-principle experiments on a 1/16 scale miniaturized Charpy test. In order to benchmark the laser welding procedure, the laser-reconstituted specimen data have been compared with the original specimen data. In addition, the microstructure after welding has been examined to ensure that the material in the vicinity of the notch is essentially unchanged after the welding process. Data which characterize the thermal transient during welding are obtained by attaching thermocouples to the specimens. Other important considerations include perturbation of the stress field near the notch, dynamic stress waves, and contact of the weld region with the tup. Precise control of welding parameters has been demonstrated, heat-affected zones as small as 0.25 mm can be achieved, and sufficient penetration depth can be obtained to enable welding thick sections (1T or greater) to yield conventional Charpy specimens or fracture toughness specimens and thin sections (∼5 mm) to yield Miniaturized Notch Test (MNT) specimens

  3. A new giant titanosaur sheds light on body mass evolution among sauropod dinosaurs.

    Science.gov (United States)

    Carballido, José L; Pol, Diego; Otero, Alejandro; Cerda, Ignacio A; Salgado, Leonardo; Garrido, Alberto C; Ramezani, Jahandar; Cúneo, Néstor R; Krause, Javier M

    2017-08-16

    Titanosauria was the most diverse and successful lineage of sauropod dinosaurs. This clade had its major radiation during the middle Early Cretaceous and survived up to the end of that period. Among sauropods, this lineage has the most disparate values of body mass, including the smallest and largest sauropods known. Although recent findings have improved our knowledge on giant titanosaur anatomy, there are still many unknown aspects about their evolution, especially for the most gigantic forms and the evolution of body mass in this clade. Here we describe a new giant titanosaur, which represents the largest species described so far and one of the most complete titanosaurs. Its inclusion in an extended phylogenetic analysis and the optimization of body mass reveals the presence of an endemic clade of giant titanosaurs inhabited Patagonia between the Albian and the Santonian. This clade includes most of the giant species of titanosaurs and represents the major increase in body mass in the history of Titanosauria. © 2017 The Author(s).

  4. Advances in miniature spectrometer and sensor development

    Science.gov (United States)

    Malinen, Jouko; Rissanen, Anna; Saari, Heikki; Karioja, Pentti; Karppinen, Mikko; Aalto, Timo; Tukkiniemi, Kari

    2014-05-01

    Miniaturization and cost reduction of spectrometer and sensor technologies has great potential to open up new applications areas and business opportunities for analytical technology in hand held, mobile and on-line applications. Advances in microfabrication have resulted in high-performance MEMS and MOEMS devices for spectrometer applications. Many other enabling technologies are useful for miniature analytical solutions, such as silicon photonics, nanoimprint lithography (NIL), system-on-chip, system-on-package techniques for integration of electronics and photonics, 3D printing, powerful embedded computing platforms, networked solutions as well as advances in chemometrics modeling. This paper will summarize recent work on spectrometer and sensor miniaturization at VTT Technical Research Centre of Finland. Fabry-Perot interferometer (FPI) tunable filter technology has been developed in two technical versions: Piezoactuated FPIs have been applied in miniature hyperspectral imaging needs in light weight UAV and nanosatellite applications, chemical imaging as well as medical applications. Microfabricated MOEMS FPIs have been developed as cost-effective sensor platforms for visible, NIR and IR applications. Further examples of sensor miniaturization will be discussed, including system-on-package sensor head for mid-IR gas analyzer, roll-to-roll printed Surface Enhanced Raman Scattering (SERS) technology as well as UV imprinted waveguide sensor for formaldehyde detection.

  5. Miniaturization of components and systems for space using MEMS-technology

    Science.gov (United States)

    Grönland, Tor-Arne; Rangsten, Pelle; Nese, Martin; Lang, Martin

    2007-06-01

    Development of MEMS-based (micro electro mechanical system) components and subsystems for space applications has been pursued by various research groups and organizations around the world for at least two decades. The main driver for developing MEMS-based components for space is the miniaturization that can be achieved. Miniaturization can not only save orders of magnitude in mass and volume of individual components, but it can also allow increased redundancy, and enable novel spacecraft designs and mission scenarios. However, the commercial breakthrough of MEMS has not occurred within the space business as it has within other branches such as the IT/telecom or automotive industries, or as it has in biotech or life science applications. A main explanation to this is the highly conservative attitude to new technology within the space community. This conservatism is in many senses motivated by a very low risk acceptance in the few and costly space projects that actually ends with a space flight. To overcome this threshold there is a strong need for flight opportunities where reasonable risks can be accepted. Currently there are a few flight opportunities allowing extensive use of new technology in space, but one of the exceptions is the PRISMA program. PRISMA is an international (Sweden, Germany, France, Denmark, Norway, Greece) technology demonstration program with focus on rendezvous and formation flying. It is a two satellite LEO mission with a launch scheduled for the first half of 2009. On PRISMA, a number of novel technologies e.g. RF metrology sensor for Darwin, autonomous formation flying based on GPS and vision-based sensors, ADN-based "green propulsion" will be demonstrated in space for the first time. One of the satellites will also have a miniaturized propulsion system onboard based on MEMS-technology. This novel propulsion system includes two microthruster modules, each including four thrusters with micro- to milli-Newton thrust capability. The novelty

  6. Cartilage of the Intervertebral Disc Eng-Plate, A Histological, Histochemical, Fine Structure Study.

    Science.gov (United States)

    1982-08-01

    degeneration (Nachemson et al., 1970). These and related studies consider the end-plates to be composed of hyaline cartilage and thus homologues of articular...results of this study in rhesus indicate, that while present, the cartilage of the end-plate is quite different in structure and presumably...HZSTOLO6ZCAL,-ETCfU) I AUG 82 N 5 NUSSBAUM IUNCLASSIFDATRL8R-1222NL.rnximommmB~iIEND2 AFAMRL-TR-81 - 122 " CARTILAGE OF THE INTERVERTEBRAL DISC END-PLATE A

  7. Multinucleated Giant Cancer Cells Produced in Response to Ionizing Radiation Retain Viability and Replicate Their Genome

    Directory of Open Access Journals (Sweden)

    Razmik Mirzayans

    2017-02-01

    Full Text Available Loss of wild-type p53 function is widely accepted to be permissive for the development of multinucleated giant cells. However, whether therapy-induced multinucleation is associated with cancer cell death or survival remains controversial. Herein, we demonstrate that exposure of p53-deficient or p21WAF1 (p21-deficient solid tumor-derived cell lines to ionizing radiation (between 2 and 8 Gy results in the development of multinucleated giant cells that remain adherent to the culture dish for long times post-irradiation. Somewhat surprisingly, single-cell observations revealed that virtually all multinucleated giant cells that remain adherent for the duration of the experiments (up to three weeks post-irradiation retain viability and metabolize 3-(4,5-dimethylthiazol-2-yl-2,5-diphenyl-tetrazolium bromide (MTT, and the majority (>60% exhibit DNA synthesis. We further report that treatment of multinucleated giant cells with pharmacological activators of apoptosis (e.g., sodium salicylate triggers their demise. Our observations reinforce the notion that radiation-induced multinucleation may reflect a survival mechanism for p53/p21-deficient cancer cells. With respect to evaluating radiosensitivity, our observations underscore the importance of single-cell experimental approaches (e.g., single-cell MTT as the creation of viable multinucleated giant cells complicates the interpretation of the experimental data obtained by commonly-used multi-well plate colorimetric assays.

  8. PWR integral tie plate and locking mechanism

    International Nuclear Information System (INIS)

    Flora, B.S.; Osborne, J.L.

    1980-01-01

    A locking mechanism for securing an upper tie plate to the tie rods of a nuclear fuel bundle is described. The mechanism includes an upper tie plate assembly and locking sleeves fixed to the ends of the tie rods. The tie plate is part of the upper tie plate assembly and is secured to the fuel bundle by securing the entire upper tie plate assembly to the locking sleeves fixed to the tie rods. The assembly includes, in addition to the tie plate, locking nuts for engaging the locking sleeves, retaining sleeves to operably connect the locking nuts to the assembly, a spring biased reaction plate to restrain the locking nuts in the locked position and a means to facilitate the removal of the entire assembly as a unit from the fuel bundle

  9. Characterisation of a ultra-miniature counter for microdosimetric measurements in a therapeutic 400 MeV/A carbon beam

    International Nuclear Information System (INIS)

    Endo, S.; Takada, M.; Ishikawa, M.; Hoshi, M.; Uehara, S.; Yamaguchi, H.; Kanai, T.; Matsufji, N.; Shizuma, K.; Onizuka, Y.

    2002-01-01

    Single event spectra of a clinical carbon beam have been measured by an ultra-miniature tissue-equivalent proportional counter (UMC). In order to cover the energy range of the Bragg peak, the incident energy of the carbon beam was degraded by aluminium plates. Single event spectra for carbon-events incident to the UMC were analysed and selected at several carbon energies using thin scintillation counters. It was found that the dose weighted lineal energy distributions have a doublet peak structure due to incident carbon beam and fragment contributions. (author)

  10. Dilatation operator and the Super Yang-Mills duals of open strings on AdS giant gravitons

    International Nuclear Information System (INIS)

    Correa, Diego H.; Silva, Guillermo A.

    2006-01-01

    We study the one-loop anomalous dimensions of the Super Yang-Mills dual operators to open strings ending on AdS giant gravitons. AdS giant gravitons have no upper bound for their angular momentum and we represent them by the contraction of scalar fields, carrying the appropriate R-charge, with a totally symmetric tensor. We represent the open string motion along AdS directions by appending to the giant graviton operator a product of fields including covariant derivatives. We derive a bosonic lattice Hamiltonian that describes the mixing of these excited AdS giants operators under the action of the one-loop dilatation operator of N = 4 SYM. This Hamiltonian captures several intuitive differences with respect to the case of sphere giant gravitons. A semiclassical analysis of the Hamiltonian allows us to give a geometrical interpretation for the labeling used to describe the fields products appended to the AdS giant operators. It also allows us to show evidence for the existence of continuous bands in the Hamiltonian spectrum

  11. Discussion about effecting of stiffener in four bolts in a row end plate connection for long span and heavy load steel structures in Vietnam

    Science.gov (United States)

    Huong, Khang T.; Nguyen, Cung H.

    2018-04-01

    Nowadays, steel structure industry in Vietnam is in strong development. The construction of steel structure becomes larger span and heavier load. The issue spawned a number of issues arise from optimizing connections. Typical of steel connections in prefabricated steel structure that is an end plate (face plate) bolted connection. When the connection carried a heavy load, then the number of bolts is required much more. Increasing the number of rows bolts will less effective because can still not enough strength requirements, the bolts in row near rotational center will level arm reduction, then it cannot carry heavy loads. The current solution is doing multiple bolts in a row. Current standards such as EN [1], AISC [2] are no specific guidelines for calculating the connection four bolts in a row that primarily assumes the way works like a T-stub of the two bolts a row. Some articles studied T-stub four bolts in a row [3], [4], [5], [6] by component method but it has some components which weren’t considered. In this paper, in order to provide a contribution to improve the T-stub four bolts in a row, the stiffener component in T-stub will be added and compared with T-stub without stiffener by the finite element model to demonstrate effectiveness in reducing stress and displacement of T-stub. It gives ideas for the economic design of four bolts in a row end plate connection in Vietnam for future.

  12. The Okhotsk Plate and the Eurasia-North America plate boundary zone.

    Science.gov (United States)

    Hindle, David; Mackey, Kevin

    2014-05-01

    The Eurasia-North America plate boundary zone transitions from spreading at rates of ~ 25mm/yr in the North Atlantic, to compression at rates of ~ 5mm/yr in the region of the Okhotsk plate. Because the pole of rotation between Eurasia and North America lies more or less on their mutual boundary, there is a linear change in rate along the boundary, and regions near the euler pole are subject to extremely low deformation rates. The Okhotsk - Eurasia - North America triple junction lies slightly south of the rotation pole, placing the Okhotsk plate entirely in a weakly contractional setting. Regions near the triple junction absorb 1mm/yr contraction. Further south, towards the shoreline of the Okhotsk sea, up to 5 mm/yr contraction may be absorbed within the plate. How shortening is accommodated across the boundary remains an open question. One possibility is wholesale extrusion of the entire Okhotsk plate (or possibly its northwestern corner) along two plate boundary strike slip faults (Eurasia-Okhostk and North America Okhotsk). The problem with this model is that the seismic record does not presently clearly support it, with the largest events distributed both within the plate interior and on its boundaries. This may suggest that instead, the Okhotsk plate, and particularly its north-western end, consists of a series of smaller blocks which shuffle against each other, partially accommodating extrusion, but also permitting some internal deformation and change of shape of the Okhotsk plate itself. We present analyses of the very sparse seismic record from the region, as well as geometric-kinematic, tectonic models of the possible deformation of northwest Okhotsk to try to better understand the different probabilities of how this slowly deforming plate boundary zone is behaving.

  13. Front-End ASICs for 3-D Ultrasound : From Beamforming to Digitization

    NARCIS (Netherlands)

    Chen, C.

    2018-01-01

    This thesis describes the analysis, design and evaluation of front-end application-specific integrated circuits (ASICs) for 3-D medical ultrasound imaging, with the focus on the receive electronics. They are specifically designed for next-generation miniature 3-D ultrasound devices, such as

  14. Miniaturized GPS/MEMS IMU integrated board

    Science.gov (United States)

    Lin, Ching-Fang (Inventor)

    2012-01-01

    This invention documents the efforts on the research and development of a miniaturized GPS/MEMS IMU integrated navigation system. A miniaturized GPS/MEMS IMU integrated navigation system is presented; Laser Dynamic Range Imager (LDRI) based alignment algorithm for space applications is discussed. Two navigation cameras are also included to measure the range and range rate which can be integrated into the GPS/MEMS IMU system to enhance the navigation solution.

  15. Miniaturizing RFID for magnamosis.

    Science.gov (United States)

    Jiang, Hao; Chen, Shijie; Kish, Shad; Loh, Lokkee; Zhang, Junmin; Zhang, Xiaorong; Kwiat, Dillon; Harrison, Michael; Roy, Shuvo

    2014-01-01

    Anastomosis is a common surgical procedure using staples or sutures in an open or laparoscopic surgery. A more effective and much less invasive alternative is to apply the mechanical pressure on the tissue over a few days [1]. Since the pressure is produced by the attractive force between two permanent magnets, the procedure is called magnamosis[1]. To ensure the two magnets are perfectly aligned during the surgery, a miniaturized batteryless Radio Frequency IDentification (RFID) tag is developed to wirelessly telemeter the status of a pressure sensitive mechanical switch. Using the multi-layer circular spiral coil design, the diameter of the RFID tag is shrunk to 10, 15, 19 and 27 mm to support the magnamosis for children as well as adults. With the impedance matching network, the operating distance of these four RFID tags are longer than 10 cm in a 20 × 22 cm(2) area, even when the tag's normal direction is 45° off the antenna's normal direction. Measurement results also indicate that there is no noticeable degradation on the operating distance when the tag is immersed in saline or placed next to the rare-earth magnet. The miniaturized RFID tag presented in this paper is able to support the magnamosis and other medical applications that require the miniaturized RFID tag.

  16. Vertical steam generator with slab-type tube-plate with even tube bundle washing

    International Nuclear Information System (INIS)

    Manek, O.; Masek, V.; Motejl, V.; Quitta, R.

    1980-01-01

    A shielding plate supporting the tubes attached to the tube plate of a vertical steam generator is mounted above the tube plate. Tube sleeves are designed with a dimensional tolerance relative to the heat transfer tubes and the sleeve end and the tube plate end. A separate space is thus formed above the tube plate in which circulation or feed water is introduced to flow between the branch and the heat transfer tube. This provides intensive washing of heat transfer tubes at a critical point and prevents deposit formation, thus excluding heat transfer tube failures. (J.B.)

  17. Formation of Ice Giant Satellites During Thommes Model Mirgration

    Science.gov (United States)

    Fuse, Christopher; Spiegelberg, Josephine

    2018-01-01

    Inconsistencies between ice giant planet characteristics and classic planet formation theories have led to a re-evaluation of the formation of the outer Solar system. Thommes model migration delivers proto-Uranus and Neptune from orbits interior to Saturn to their current locations. The Thommes model has also been able to reproduce the large Galilean and Saturnian moons via interactions between the proto-ice giants and the gas giant moon disks.As part of a series of investigations examining the effects of Thommes model migration on the formation of moons, N-body simulations of the formation of the Uranian and Neptunian satellite systems were performed. Previous research has yielded conflicting results as to whether satellite systems are stable during planetary migration. Some studies, such as Beaugé (2002) concluded that the system was not stable over the proposed duration of migration. Conversely, Fuse and Neville (2011) and Yokoyama et al. (2011) found that moons were retained, though the nature of the resulting system was heavily influenced by interactions with planetesimals and other large objects. The results of the current study indicate that in situ simulations of the Uranus and Neptune systems can produce stable moons. Whether with current orbital parameters or located at pre-migration, inner Solar system semi-major axes, the simulations end with 5.8 ± 0.15 or 5.9 ± 0.7 regular satellites around Uranus and Neptune, respectively. Preliminary simulations of a proto-moon disk around a single planet migrating via the Thommes model have failed to retain moons. Furthermore, simulations of ejection of the current Uranian satellite system retained at most one moon. Thus, for the Thommes model to be valid, it is likely that moon formation did not begin until after migration ended. Future work will examine the formation of gas and ice giant moons through other migration theories, such as the Nice model (Tsiganis et al. 2006).

  18. Giant basal cell carcinoma of the eyelid: a case history | Fetohi | Pan ...

    African Journals Online (AJOL)

    Giant basal cell carcinoma of the eyelid: a case history. ... Abstract. Basal cell carcinoma is a type of skin cancer and rare, aggressive forms of basal cell ... She died 09 months after the end of irradiation in Intensive care unit due to septic shock.

  19. Mechanisms of growth plate maturation and epiphyseal fusion

    NARCIS (Netherlands)

    Emons, J.; Chagin, A.S.; Karperien, Hermanus Bernardus Johannes; Wit, J.M.

    2011-01-01

    Longitudinal growth occurs within the long bones at the growth plate. During childhood, the growth plate matures, its total width decreases and eventually it disappears at the end of puberty with complete replacement by bone along with cessation of longitudinal growth. The exact mechanism of

  20. THE REDSHIFT DISTRIBUTION OF GIANT ARCS IN THE SLOAN GIANT ARCS SURVEY

    International Nuclear Information System (INIS)

    Bayliss, Matthew B.; Gladders, Michael D.; Koester, Benjamin P.; Oguri, Masamune; Hennawi, Joseph F.; Sharon, Keren; Dahle, Haakon

    2011-01-01

    We measure the redshift distribution of a sample of 28 giant arcs discovered as a part of the Sloan Giant Arcs Survey. Gemini/GMOS-North spectroscopy provides precise redshifts for 24 arcs, and 'redshift desert' constrains for the remaining 4 arcs. This is a direct measurement of the redshift distribution of a uniformly selected sample of bright giant arcs, which is an observable that can be used to inform efforts to predict giant arc statistics. Our primary giant arc sample has a median redshift z = 1.821 and nearly two-thirds of the arcs, 64%, are sources at z ∼> 1.4, indicating that the population of background sources that are strongly lensed into bright giant arcs resides primarily at high redshift. We also analyze the distribution of redshifts for 19 secondary strongly lensed background sources that are not visually apparent in Sloan Digital Sky Survey imaging, but were identified in deeper follow-up imaging of the lensing cluster fields. Our redshift sample for the secondary sources is not spectroscopically complete, but combining it with our primary giant arc sample suggests that a large fraction of all background galaxies that are strongly lensed by foreground clusters reside at z ∼> 1.4. Kolmogorov-Smirnov tests indicate that our well-selected, spectroscopically complete primary giant arc redshift sample can be reproduced with a model distribution that is constructed from a combination of results from studies of strong-lensing clusters in numerical simulations and observational constraints on the galaxy luminosity function.

  1. Giant CP stars

    International Nuclear Information System (INIS)

    Loden, L.O.; Sundman, A.

    1989-01-01

    This study is part of an investigation of the possibility of using chemically peculiar (CP) stars to map local galactic structure. Correct luminosities of these stars are therefore crucial. CP stars are generally regarded as main-sequence or near-main-sequence objects. However, some CP stars have been classified as giants. A selection of stars, classified in literature as CP giants, are compared to normal stars in the same effective temperature interval and to ordinary 'non giant' CP stars. There is no clear confirmation of a higher luminosity for 'CP giants', than for CP stars in general. In addition, CP characteristics seem to be individual properties not repeated in a component star or other cluster members. (author). 50 refs., 5 tabs., 3 figs

  2. Numerical Study of Electrostatic Field Distortion on LPTPC End-Plates based on Bulk Micromegas Modules

    Directory of Open Access Journals (Sweden)

    Bhattacharya Purba

    2018-01-01

    Full Text Available The R&D activities for the linear collider TPC (LC-TPC are currently working on the adoption of the micro pattern devices for the gaseous amplification stage. Several beam tests have been carried out at DESY with a 5 GeV electron beam in a 1 T superconducting magnet. We worked on a large prototype TPC with an end-plate that was built, for the first time, using seven resistive bulk Micromegas modules. During experiments, reduced signal sensitivity was observed at the boundary of these modules. Electrostatic field distortion near the module boundaries was considered to be the possible major reason behind these observations. In the present work, we will explore this hypothesis through numerical simulation. Our aim has been to understand the origin of distortions observed close to the edges of the test beam modules and to explore the possibility of using the Garfield simulation framework for investigating a phenomenon as complex as distortion.

  3. Miniature x-ray source

    Science.gov (United States)

    Trebes, James E.; Bell, Perry M.; Robinson, Ronald B.

    2000-01-01

    A miniature x-ray source utilizing a hot filament cathode. The source has a millimeter scale size and is capable of producing broad spectrum x-ray emission over a wide range of x-ray energies. The miniature source consists of a compact vacuum tube assembly containing the hot filament cathode, an anode, a high voltage feedthru for delivering high voltage to the cathode, a getter for maintaining high vacuum, a connector for initial vacuum pump down and crimp-off, and a high voltage connection for attaching a compact high voltage cable to the high voltage feedthru. At least a portion of the vacuum tube wall is fabricated from highly x-ray transparent materials, such as sapphire, diamond, or boron nitride.

  4. Subduction and Plate Edge Tectonics in the Southern Caribbean

    Science.gov (United States)

    Levander, A.; Schmitz, M.; Niu, F.; Bezada, M. J.; Miller, M. S.; Masy, J.; Ave Lallemant, H. G.; Pindell, J. L.; Bolivar Working Group

    2013-05-01

    The southern Caribbean plate boundary consists of a subduction zone at at either end of a complex strike-slip fault system: In the east at the Lesser Antilles subduction zone, the Atlantic part of the South American plate subducts beneath the Caribbean. In the north and west in the Colombia basin, the Caribbean subducts under South America. In a manner of speaking, the two plates subduct beneath each other. Finite-frequency teleseismic P-wave tomography confirms this, imaging the Atlantic and the Caribbean plates subducting steeply in opposite directions to transition zone depths under northern South America (Bezada et al, 2010). The two subduction zones are connected by the El Pilar-San Sebastian strike-slip fault system, a San Andreas scale system that has been cut off at the Bocono fault, the southeastern boundary fault of the Maracaibo block. A variety of seismic probes identify subduction features at either end of the system (Niu et al, 2007; Clark et al., 2008; Miller et al. 2009; Growdon et al., 2009; Huang et al., 2010; Masy et al, 2011). The El Pilar system forms at the southeastern corner of the Antilles subduction zone with the Atlantic plate tearing from South America. The deforming plate edges control mountain building and basin formation at the eastern end of the strike-slip system. Tearing the Atlantic plate from the rest of South America appears to cause further lithospheric instability continentward. In northwestern South America the Caribbean plate very likely also tears, as its southernmost element subducts at shallow angles under northernmost Colombia but then rapidly descends to the transition zone under Lake Maracaibo (Bezada et al., 2010). We believe that the flat slab controls the tectonics of the Neogene Merida Andes, Perija, and Santa Marta ranges. The nonsubducting part of the Caribbean plate also underthrusts northern Venezuela to about the width of the coastal mountains (Miller et al., 2009). We infer that the edge of the underthrust

  5. Miniaturized polymer electrolyte fuel cell (PEFC) stack using micro structured bipolar plate

    Energy Technology Data Exchange (ETDEWEB)

    Veziridis, Z; Scherer, G G; Marmy, Ch; Glaus, F [Paul Scherrer Inst. (PSI), Villigen (Switzerland)

    1999-08-01

    In Polymer Electrolyte Fuel Cell (PEFC) technology the reducing of volume and mass of the fuel cell stack and the improvement of catalyst utilization are of great interest. These parameters affect applicability and system cost. In this work we present an alternative way for reducing the stack volume by combining gas distribution and catalytic active area in one plate. Micro machined glassy carbon electrodes serve as support material for the platinum catalyst, as well as gas distributor at the same time. A comparison of these electrodes with conventional platinum-black gas diffusion electrodes under fuel cell conditions shows that the new system is a promising electrode type for enhanced power density and catalyst utilization. (author) 3 figs., 5 refs.

  6. The effect of plate thickness, surface tension and fluid flow on detachment of drops from a plate

    NARCIS (Netherlands)

    Lexmond, A.S.; Geld, C.W.M. van der

    2005-01-01

    The pinch-off of drops from the downstream end of plates is an important re-entrainment mechanism of condensate in compact condensers. The present experimental study complements a previous one [A.S. Lexmond, C.W.M. van der Geld, The effect of fluid flow on detachment of drops from the downstream end

  7. History of internal fixation with plates (part 2): new developments after World War II; compressing plates and locked plates.

    Science.gov (United States)

    Hernigou, Philippe; Pariat, Jacques

    2017-07-01

    The first techniques of operative fracture with plates were developed in the 19th century. In fact, at the beginning these methods consisted of an open reduction of the fracture usually followed by a very unstable fixation. As a consequence, the fracture had to be opened with a real risk of (sometimes lethal) infection, and due to unstable fixation, protection with a cast was often necessary. During the period between World Wars I and II, plates for fracture fixation developed with great variety. It became increasingly recognised that, because a fracture of a long bone normally heals with minimal resorption at the bone ends, this may result in slight shortening and collapse, so a very rigid plate might prevent such collapse. However, as a consequence, delayed healing was observed unless the patient was lucky enough to have the plate break. One way of dealing with this was to use a slotted plate in which the screws could move axially, but the really important advance was recognition of the role of compression. After the first description of compression by Danis with a "coapteur", Bagby and Müller with the AO improved the technique of compression. The classic dynamic compression plates from the 1970s were the key to a very rigid fixation, leading to primary bone healing. Nevertheless, the use of strong plates resulted in delayed union and the osteoporosis, cancellous bone, comminution, and/or pathological bone resulted in some failures due to insufficient stability. Finally, new devices represented by locking plates increased the stability, contributing to the principles of a more biological osteosynthesis while giving enough stability to allow immediate full weight bearing in some patients.

  8. Miniature mass analyzer

    CERN Document Server

    Cuna, C; Lupsa, N; Cuna, S; Tuzson, B

    2003-01-01

    The paper presents the concept of different mass analyzers that were specifically designed as small dimension instruments able to detect with great sensitivity and accuracy the main environmental pollutants. The mass spectrometers are very suited instrument for chemical and isotopic analysis, needed in environmental surveillance. Usually, this is done by sampling the soil, air or water followed by laboratory analysis. To avoid drawbacks caused by sample alteration during the sampling process and transport, the 'in situ' analysis is preferred. Theoretically, any type of mass analyzer can be miniaturized, but some are more appropriate than others. Quadrupole mass filter and trap, magnetic sector, time-of-flight and ion cyclotron mass analyzers can be successfully shrunk, for each of them some performances being sacrificed but we must know which parameters are necessary to be kept unchanged. To satisfy the miniaturization criteria of the analyzer, it is necessary to use asymmetrical geometries, with ion beam obl...

  9. Miniature gamma-ray camera for tumor localization

    International Nuclear Information System (INIS)

    Lund, J.C.; Olsen, R.W.; James, R.B.; Cross, E.

    1997-08-01

    The overall goal of this LDRD project was to develop technology for a miniature gamma-ray camera for use in nuclear medicine. The camera will meet a need of the medical community for an improved means to image radio-pharmaceuticals in the body. In addition, this technology-with only slight modifications-should prove useful in applications requiring the monitoring and verification of special nuclear materials (SNMs). Utilization of the good energy resolution of mercuric iodide and cadmium zinc telluride detectors provides a means for rejecting scattered gamma-rays and improving the isotopic selectivity in gamma-ray images. The first year of this project involved fabrication and testing of a monolithic mercuric iodide and cadmium zinc telluride detector arrays and appropriate collimators/apertures. The second year of the program involved integration of the front-end detector module, pulse processing electronics, computer, software, and display

  10. Novel lipoprotein density profiling in healthy dogs of various breeds, healthy miniature schnauzers, and miniature schnauzers with hyperlipidemia

    Science.gov (United States)

    2013-01-01

    Background Despite the importance of abnormalities in lipoprotein metabolism in clinical canine medicine, the fact that most previously used methods for lipoprotein profiling are rather laborious and time-consuming has been a major obstacle to the wide clinical application and use of lipoprotein profiling in this species. The aim of the present study was to assess the feasibility of a continuous lipoprotein density profile (CLPDP) generated within a bismuth sodium ethylenediaminetetraacetic acid (NaBiEDTA) density gradient to characterize and compare the lipoprotein profiles of healthy dogs of various breeds, healthy Miniature Schnauzers, and Miniature Schnauzers with primary hypertriacylglycerolemia. A total of 35 healthy dogs of various breeds with serum triacylglycerol (TAG) and cholesterol concentrations within their respective reference intervals were selected for use as a reference population. Thirty-one Miniature Schnauzers with serum TAG and cholesterol concentrations within their respective reference intervals and 31 Miniature Schnauzers with hypertriacylglyceridemia were also included in the study. Results The results suggest that CLPDP using NaBiEDTA provides unique diagnostic information in addition to measurements of serum TAG and cholesterol concentrations and that it is a useful screening method for dogs with suspected lipoprotein metabolism disorders. Using the detailed and continuous density distribution information provided by the CLPDP, important differences in lipoprotein profiles can be detected even among dogs that have serum TAG and cholesterol concentrations within the reference interval. Miniature Schnauzers with serum TAG and cholesterol concentrations within the reference interval had significantly different lipoprotein profiles than dogs of various other breeds. In addition, it was further established that specific lipoprotein fractions are associated with hypertriacylglyceridemia in Miniature Schnauzers. Conclusions The results of the

  11. Rapid formation of gas giants, ice giants and super-Earths

    Energy Technology Data Exchange (ETDEWEB)

    Boss, A P [DTM, Carnegie Institution of Washington, 5241 Broad Branch Road, NW, Washington, DC 20015 (United States)], E-mail: boss@dtm.ciw.edu

    2008-08-15

    Giant planets might have been formed by either of the two basic mechanisms, top-down (disk instability) or bottom-up (core accretion). The latter mechanism is the most generally accepted mechanism and it begins with the collisional accumulation of solid cores that may then accrete sufficient gas to become gas giants. The former mechanism is more heretical and begins with the gravitational instability of the protoplanetary disk gas, leading to the formation of self-gravitating protoplanets, within which the dust settles to form a solid core. The disk instability mechanism has been thought of primarily as a mechanism for the formation of gas giants, but if it occurs in a disk that is being photoevaporated by the ultraviolet radiation from nearby massive stars, then the outer gaseous protoplanets can be photoevaporated as well and stripped of their gaseous envelopes. The result would then be ice giants (cold super-Earths), such as the objects discovered recently by microlensing orbiting two presumed M dwarf stars. M dwarfs that form in regions of future high-mass star formation would be expected to produce cold super-Earths orbiting at distances of several astronomical units (AU) and beyond, while M dwarfs that form in regions of low-mass star formation would be expected to have gas giants at those distances. Given that most stars are born in the former rather than in the latter regions, M dwarfs should have significantly more super-Earths than gas giants on orbits of several AU or more.

  12. Rapid formation of gas giants, ice giants and super-Earths

    International Nuclear Information System (INIS)

    Boss, A P

    2008-01-01

    Giant planets might have been formed by either of the two basic mechanisms, top-down (disk instability) or bottom-up (core accretion). The latter mechanism is the most generally accepted mechanism and it begins with the collisional accumulation of solid cores that may then accrete sufficient gas to become gas giants. The former mechanism is more heretical and begins with the gravitational instability of the protoplanetary disk gas, leading to the formation of self-gravitating protoplanets, within which the dust settles to form a solid core. The disk instability mechanism has been thought of primarily as a mechanism for the formation of gas giants, but if it occurs in a disk that is being photoevaporated by the ultraviolet radiation from nearby massive stars, then the outer gaseous protoplanets can be photoevaporated as well and stripped of their gaseous envelopes. The result would then be ice giants (cold super-Earths), such as the objects discovered recently by microlensing orbiting two presumed M dwarf stars. M dwarfs that form in regions of future high-mass star formation would be expected to produce cold super-Earths orbiting at distances of several astronomical units (AU) and beyond, while M dwarfs that form in regions of low-mass star formation would be expected to have gas giants at those distances. Given that most stars are born in the former rather than in the latter regions, M dwarfs should have significantly more super-Earths than gas giants on orbits of several AU or more

  13. Miniature Scroll Pumps Fabricated by LIGA

    Science.gov (United States)

    Wiberg, Dean; Shcheglov, Kirill; White, Victor; Bae, Sam

    2009-01-01

    Miniature scroll pumps have been proposed as roughing pumps (low - vacuum pumps) for miniature scientific instruments (e.g., portable mass spectrometers and gas analyzers) that depend on vacuum. The larger scroll pumps used as roughing pumps in some older vacuum systems are fabricated by conventional machining. Typically, such an older scroll pump includes (1) an electric motor with an eccentric shaft to generate orbital motion of a scroll and (2) conventional bearings to restrict the orbital motion to a circle. The proposed miniature scroll pumps would differ from the prior, larger ones in both design and fabrication. A miniature scroll pump would include two scrolls: one mounted on a stationary baseplate and one on a flexure stage (see figure). An electromagnetic actuator in the form of two pairs of voice coils in a push-pull configuration would make the flexure stage move in the desired circular orbit. The capacitance between the scrolls would be monitored to provide position (gap) feedback to a control system that would adjust the drive signals applied to the voice coils to maintain the circular orbit as needed for precise sealing of the scrolls. To minimize power consumption and maximize precision of control, the flexure stage would be driven at the frequency of its mechanical resonance. The miniaturization of these pumps would entail both operational and manufacturing tolerances of pump components. In addition, the vibrations of conventional motors and ball bearings exceed these tight tolerances by an order of magnitude. Therefore, the proposed pumps would be fabricated by the microfabrication method known by the German acronym LIGA ( lithographie, galvanoformung, abformung, which means lithography, electroforming, molding) because LIGA has been shown to be capable of providing the required tolerances at large aspect ratios.

  14. Giant Cell Arteritis

    Science.gov (United States)

    Giant cell arteritis is a disorder that causes inflammation of your arteries, usually in the scalp, neck, and arms. ... arteries, which keeps blood from flowing well. Giant cell arteritis often occurs with another disorder called polymyalgia ...

  15. History of the stellar birthrate from lithium abundances in red giants

    International Nuclear Information System (INIS)

    Scalo, J.M.; Miller, G.E.

    1980-01-01

    The lithium abundance at the end of main-sequence evolution should increase strongly with mass for masses less than 1.4 M/sub sun/. It is shown that because of this dependence the frequency distribution of Li abundances in red giants is a sensitive probe of the history of the stellar birthrate in the solar neighborhood since the Li distribution directly reflects the stellar age distribution. A birthrate which decreases with time gives a smaller mean red giant Li abundance than an increasing birthrate because a larger fraction of red giants are older and hence less massive. Theoretical Li abundance frequency distributions are calculated for exponentially increasing, constant, and exponentially decreasing birthrates using a semiempirical prescription for main-sequence Li destruction, theoretical main-sequence lifetimes and red giant dilution factors, and self-consistent initial mass functions. The results are compared with the observed abundance distribution for 35 giants studied by Lambert and his colleagues. Allowing for uncertainties, we find that the ratio of present birthrate to average past birthrate has a value between 0.5 and 2. These limits are consistent with results of most other methods of determining the birthrate history, but the present method provides a considerably more stringent lower limit. It is also shown that, with more observational data, fluctuations in the birthrate with a time scale of about one billion years during the period between two and six billion years ago could be resolved

  16. End Ordovician extinctions

    DEFF Research Database (Denmark)

    Harper, David A. T.; Hammarlund, Emma; Rasmussen, Christian M. Ø.

    2014-01-01

    -global anoxia associated with a marked transgression during the Late Hirnantian. Most recently, however, new drivers for the extinctions have been proposed, including widespread euxinia together with habitat destruction caused by plate tectonic movements, suggesting that the end Ordovician mass extinctions were...

  17. FY 2006 Miniature Spherical Retroreflectors Final Report

    Energy Technology Data Exchange (ETDEWEB)

    Anheier, Norman C.; Bernacki, Bruce E.; Krishnaswami, Kannan

    2006-12-28

    Research done by the Infrared Photonics team at Pacific Northwest National Laboratory (PNNL) is focused on developing miniature spherical retroreflectors using the unique optical and material properties of chalcogenide glass to reduce both performance limiting spherical aberrations. The optimized optical performance will provide efficient signal retroreflection that enables a broad range of remote detection scenarios for mid-wave infrared (MWIR) and long-wave infrared (LWIR) sensing applications. Miniature spherical retroreflectors can be developed to aid in the detection of signatures of nuclear proliferation or other chemical vapor or radiation signatures. Miniature spherical retroreflectors are not only well suited to traditional LIDAR methods for chemical plume detection and identification, but could enable remote detection of difficult semi-volatile chemical materials or low level radiation sources.

  18. PROBING THE DEEP END OF THE MILKY WAY WITH KEPLER : ASTEROSEISMIC ANALYSIS OF 854 FAINT RED GIANTS MISCLASSIFIED AS COOL DWARFS

    Energy Technology Data Exchange (ETDEWEB)

    Mathur, S. [Space Science Institute, 4750 Walnut Street, Suite 205, Boulder, CO 80301 (United States); García, R. A.; Beck, P. G.; Houmani, K.; Salabert, D. [Laboratoire AIM, CEA/DRF-CNRS-Université Paris Diderot, IRFU/SAp, Centre de Saclay, F-91191 Gif-sur-Yvette Cedex (France); Huber, D.; Stello, D. [Sydney Institute for Astronomy (SIfA), School of Physics, University of Sydney, NSW 2006 (Australia); Regulo, C. [Universidad de La Laguna, Dpto de Astrofísica, E-38206, Tenerife (Spain)

    2016-08-10

    Asteroseismology has proven to be an excellent tool to determine not only global stellar properties with good precision, but also to infer the stellar structure, dynamics, and evolution for a large sample of Kepler stars. Prior to the launch of the mission, the properties of Kepler targets were inferred from broadband photometry, leading to the Kepler Input Catalog (KIC). The KIC was later revised in the Kepler Star Properties Catalog, based on literature values and an asteroseismic analysis of stars that were unclassified in the KIC. Here, we present an asteroseismic analysis of 45,400 stars that were classified as dwarfs in the Kepler Star Properties Catalog. We found that around 2% of the sample shows acoustic modes in the typical frequency range that put them in the red-giant category rather than the cool dwarf category. We analyze the asteroseismic properties of these stars, derive their surface gravities, masses, and radii, and present updated effective temperatures and distances. We show that the sample is significantly fainter than the previously known oscillating giants in the Kepler field, with the faintest stars reaching down to a Kepler magnitude of Kp ∼ 16. We demonstrate that 404 stars are at distances beyond 5 kpc and that the stars are significantly less massive than for the original Kepler red-giant sample, consistent with a population of distant halo giants. A comparison with a galactic population model shows that up to 40 stars might be genuine halo giants, which would increase the number of known asteroseismic halo stars by a factor of 4. The detections presented here will provide a valuable sample for galactic archeology studies.

  19. Eopolydiexodina (Middle Permian giant fusulinids) from Afghanistan: Biometry, morphometry, paleobiogeography, and end-Guadalupian events

    Science.gov (United States)

    Colpaert, Clémentine; Monnet, Claude; Vachard, Daniel

    2015-04-01

    the biostratigraphic revision of other large Capitanian fusulinids, permit to suggest that the end-Guadalupian event is most probably a protracted succession of last appearance data of giant genera rather than an instantaneous Lilliput effect at the Capitanian/Wuchiapingian boundary.

  20. Miniature radioactive light source

    International Nuclear Information System (INIS)

    Caffarella, T.E.; Radda, G.J.; Dooley, H.H.

    1980-01-01

    A miniature radioactive light source for illuminating digital watches is described consisting of a glass tube with improved laser sealing and strength containing tritium gas and a transducer responsive to the gas. (U.K.)

  1. Dynamic plate osteosynthesis for fracture stabilization: how to do it

    Directory of Open Access Journals (Sweden)

    Juerg Sonderegger

    2010-01-01

    Full Text Available Plate osteosynthesis is one treatment option for the stabilization of long bones. It is widely accepted to achieve bone healing with a dynamic and biological fixation where the perfusion of the bone is left intact and micromotion at the fracture gap is allowed. The indications for a dynamic plate osteosynthesis include distal tibial and femoral fractures, some midshaft fractures, and adolescent tibial and femoral fractures with not fully closed growth plates. Although many lower limb shaft fractures are managed successfully with intramedullary nails, there are some important advantages of open-reduction-and-plate fixation: the risk of malalignment, anterior knee pain, or nonunion seems to be lower. The surgeon performing a plate osteosynthesis has the possibility to influence fixation strength and micromotion at the fracture gap. Long plates and oblique screws at the plate ends increase fixation strength. However, the number of screws does influence stiffness and stability. Lag screws and screws close to the fracture site reduce micromotion dramatically. Dynamic plate osteosynthesis can be achieved by applying some simple rules: long plates with only a few screws should be used. Oblique screws at the plate ends increase the pullout strength. Two or three holes at the fracture site should be omitted. Lag screws, especially through the plate, must be avoided whenever possible. Compression is not required. Locking plates are recommended only in fractures close to the joint. When respecting these basic concepts, dynamic plate osteosynthesis is a safe procedure with a high healing and a low complication rate. 

  2. High thermal load receiving heat plate

    International Nuclear Information System (INIS)

    Shibutani, Jun-ichi; Shibayama, Kazuhito; Yamamoto, Keiichi; Uchida, Takaho.

    1993-01-01

    The present invention concerns a high thermal load heat receiving plate such as a divertor plate of a thermonuclear device. The high thermal load heat receiving plate of the present invention has a cooling performance capable of suppressing the temperature of an armour tile to less than a threshold value of the material against high thermal loads applied from plasmas. Spiral polygonal pipes are inserted in cooling pipes at a portion receiving high thermal loads in the high temperature load heat receiving plate of the present invention. Both ends of the polygonal pipes are sealed by lids. An area of the flow channel in the cooling pipes is thus reduced. Heat conductivity on the cooling surface of the cooling pipes is increased in the high thermal load heat receiving plate having such a structure. Accordingly, temperature elevation of the armour tile can be suppressed. (I.S.)

  3. Presynaptic miniature GABAergic currents in developing interneurons.

    Science.gov (United States)

    Trigo, Federico F; Bouhours, Brice; Rostaing, Philippe; Papageorgiou, George; Corrie, John E T; Triller, Antoine; Ogden, David; Marty, Alain

    2010-04-29

    Miniature synaptic currents have long been known to represent random transmitter release under resting conditions, but much remains to be learned about their nature and function in central synapses. In this work, we describe a new class of miniature currents ("preminis") that arise by the autocrine activation of axonal receptors following random vesicular release. Preminis are prominent in gabaergic synapses made by cerebellar interneurons during the development of the molecular layer. Unlike ordinary miniature postsynaptic currents in the same cells, premini frequencies are strongly enhanced by subthreshold depolarization, suggesting that the membrane depolarization they produce belongs to a feedback loop regulating neurotransmitter release. Thus, preminis could guide the formation of the interneuron network by enhancing neurotransmitter release at recently formed synaptic contacts. Copyright 2010 Elsevier Inc. All rights reserved.

  4. Postirradiation examination of high-U-loaded, low-enriched U3O8, UAl2, and U3Si test fuel plates

    International Nuclear Information System (INIS)

    Gomez, J.; Morando, R.; Perez, E.E.; Giorsetti, D.R.; Copeland, G.L.; Hofman, G.L.; Snelgrove, J.L.

    1985-01-01

    The scope of this work is to present an evaluation of the postirradiation examination of the second set of high-U-loaded, low-enriched U 3 O 8 , UAl 2 and U 3 Si miniature plates manufactured by the Comision Nacional de Energia Atomica (CNEA) of Argentina, and irradiated and examined, within the framework of the Reduced Enrichment Research and Test Reactor (RERTR) Program, at Oak Ridge National Laboratory and Argonne National Laboratory. This paper includes fabrication details of the plates, their irradiation history and the results of postirradiation examination which are compared to those of the previous test and to present results from other laboratories participating in the RERTR Program. Postirradiation examination of these plates showed satisfactory performance for the oxides, aluminides and silicides (except for the highest-loaded U 3 Si plate) with the only indication of detrimental behavior being the slight bowing of some plates at about 80% burnup

  5. Postirradiation examination of high-U-loaded, low-enriched U3O8, UAl2, and U3Si test fuel plates

    International Nuclear Information System (INIS)

    Gomez, J.; Morando, R.; Perez, E.E.; Giorsetti, D.R.; Copeland, G.L.; Hofman, G.L.; Snelgrove, J.L.

    1985-01-01

    The scope of this work is to present an evaluation of the postirradiation examination of the second set of high-U-loaded, low-enriched U 3 O 8 , UAl 2 and U 3 Si miniature plates manufactured by the Comision Nacional de Energia Atomica (CNEA) of Argentina, and irradiated and examined, within the framework of the Reduced Enrichment Research and Test Reactor (RERTR) Program, at Oak Ridge National Laboratory and Argonne National Laboratory. This paper includes fabrication details of the plates, their irradiation history and the results of postirradiation examination which are compared to those of the previous test and to present results from other laboratories participating in the REM Program. Postirradiation examination of these plates showed satisfactory performance for the oxides, aluminides and silicides (except for the highest-loaded U 3 Si plate) with the only indication of detrimental behavior being the slight bowing of some plates at about 80% burnup. (author)

  6. Postirradiation examination of high-U-loaded low-enriched U3O8, UAl2, and U3Si test fuel plates

    International Nuclear Information System (INIS)

    Gomez, J.; Morando, R.; Perez, E.E.; Giorsetti, D.R.; Copeland, G.L.; Hofmann, G.; Snelgrove, J.L.

    1984-01-01

    The scope of this work is to present an evaluation of the postirradiation examination of the second set of high-U-loaded low-enriched U 3 O 8 , UAl 2 and U 3 Si miniature plates manufactured by the Comision Nacional de Energia Atomica (CNEA) of Argentina, and irradiated and examinated, within the framework of the Reduced Enrichment Research and Test Reactor (RERTR) Program, at Oak Ridge National Laboratory and Argonne National Laboratory. This paper includes fabrication details of the plates, their irradiation history and the results of postirradiation examination which are compared to those of the previous test and to present results from other laboratories participating in the RERTR Program. Postirradiation examination of these plates showed satisfactory poerformance for the oxides, aluminides and silicides (except for the highest-loaded U 3 Si plate) with the only indication of detrimental behavior during the slight bowing of some plates at about 80% burnup

  7. Miniature Centrifugal Compressor

    Science.gov (United States)

    Sixsmith, Herbert

    1989-01-01

    Miniature turbocompressor designed for reliability and long life. Cryogenic system includes compressor, turboexpander, and heat exchanger provides 5 W of refrigeration at 70 K from 150 W input power. Design speed of machine 510,000 rpm. Compressor has gas-lubricated journal bearings and magnetic thrust bearing. When compressor runs no bearing contact and no wear.

  8. Goniometry and Limb Girth in Miniature Dachshunds

    OpenAIRE

    Thomovsky, Stephanie A.; Chen, Annie V.; Kiszonas, Alecia M.; Lutskas, Lori A.

    2016-01-01

    Purpose. To report the mean and median pelvic limb joint angles and girth measurements in miniature Dachshunds presenting with varying degrees of pelvic limb weakness secondary to thoracolumbar intervertebral disc extrusion. Methods. 15 miniature Dachshunds who presented to WSU-VTH for thoracolumbar disc extrusion. Dachshunds varied in neurologic status from ambulatory paraparetic to paraplegic at the time of measurements. Results. There were no significant differences in joint angles or girt...

  9. Miniaturized Environmental Monitoring Instrumentation

    Energy Technology Data Exchange (ETDEWEB)

    C. B. Freidhoff

    1997-09-01

    The objective of the Mass Spectrograph on a Chip (MSOC) program is the development of a miniature, multi-species gas sensor fabricated using silicon micromachining technology which will be orders of magnitude smaller and lower power consumption than a conventional mass spectrometer. The sensing and discrimination of this gas sensor are based on an ionic mass spectrograph, using magnetic and/or electrostatic fields. The fields cause a spatial separation of the ions according to their respective mass-to-charge ratio. The fabrication of this device involves the combination of microelectronics with micromechanically built sensors and, ultimately, vacuum pumps. The prototype of a chemical sensor would revolutionize the method of performing environmental monitoring for both commercial and government applications. The portable unit decided upon was the miniaturized gas chromatograph with a mass spectrometer detector, referred to as a GC/MS in the analytical marketplace.

  10. Hard X-ray sources from miniature plasma focus devices

    International Nuclear Information System (INIS)

    Raspa, V.; Silva, P.; Moreno, J.; Zambra, M.; Soto, L.

    2004-01-01

    As first stage of a program to design a repetitive pulsed radiation generator for industrial applications, two miniature plasma foci have been designed and constructed at the Chilean commission of nuclear energy. The devices operate at an energy level of the order of tens of joules (PF-50 J, 160 nF capacitor bank, 20-35 kV, 32-100 J, ∼ 150 ns time to peak current) and hundred of joules (PF-400 J, 880 nF, 20-35 kV, 176-539 J, ∼ 300 ns time to peak current). Hard X-rays are being studied in these devices operating with hydrogen. Images of metallic plates with different thickness were obtained on commercial radiographic film, Agfa Curix ST-G2, in order to characterize the energy of the hard X-ray outside of the discharge chamber of PF-400 J. An effective energy of the order of 90 keV was measured under those conditions. X ray images of different metallic objects also have been obtained. (authors)

  11. Hard X-ray sources from miniature plasma focus devices

    Energy Technology Data Exchange (ETDEWEB)

    Raspa, V. [Buenos Aires Univ., PLADEMA, CONICET and INFIP (Argentina); Silva, P.; Moreno, J.; Zambra, M.; Soto, L. [Comision Chilena de Energia Nuclear, Santiago (Chile)

    2004-07-01

    As first stage of a program to design a repetitive pulsed radiation generator for industrial applications, two miniature plasma foci have been designed and constructed at the Chilean commission of nuclear energy. The devices operate at an energy level of the order of tens of joules (PF-50 J, 160 nF capacitor bank, 20-35 kV, 32-100 J, {approx} 150 ns time to peak current) and hundred of joules (PF-400 J, 880 nF, 20-35 kV, 176-539 J, {approx} 300 ns time to peak current). Hard X-rays are being studied in these devices operating with hydrogen. Images of metallic plates with different thickness were obtained on commercial radiographic film, Agfa Curix ST-G2, in order to characterize the energy of the hard X-ray outside of the discharge chamber of PF-400 J. An effective energy of the order of 90 keV was measured under those conditions. X ray images of different metallic objects also have been obtained. (authors)

  12. Antenna Miniaturization with MEMS Tunable Capacitors

    DEFF Research Database (Denmark)

    Barrio, Samantha Caporal Del; Morris, Art; Pedersen, Gert Frølund

    2014-01-01

    In today’s mobile device market, there is a strong need for efficient antenna miniaturization. Tunable antennas are a very promising way to reduce antenna volume while enlarging its operating bandwidth. MEMS tunable capacitors are state-ofthe- art in terms of insertion loss and their characterist......In today’s mobile device market, there is a strong need for efficient antenna miniaturization. Tunable antennas are a very promising way to reduce antenna volume while enlarging its operating bandwidth. MEMS tunable capacitors are state-ofthe- art in terms of insertion loss...

  13. Use of miniature and standard specimens to evaluate effects of irradiation temperature on pressure vessel steels

    International Nuclear Information System (INIS)

    Haggag, F.M.; Nanstad, R.K.; Byrne, S.T.

    1991-01-01

    The effects of neutron irradiation on the steel reactor vessel for the modular high-temperature gas-cooled reactor (MHTGR) are being investigated, primarily because the operating temperatures are low [121 to 210 degrees C (250--410 degrees F)] compared to those for commercial light-water reactors (LWRs) [∼288 degrees C (550 degrees F)]. The need for design data on the reference temperature shift necessitated the irradiation at different temperatures of A 533 grade B class 1 plate. A 508 class 3 forging, and welds used for the vessel shell, vessel closure head, the vessel flange. This paper presents results from the first four irradiation capsules of this program. The four capsules were irradiated in the University of Buffalo Reactor to an effective fast fluence of 1 x10 18 neutron/cm 2 [0.68 x 10 18 neutron/cm 2 (>1 MeV)] at temperatures of 288, 204, 163, and 121 degrees C (550, 400, 325, and 250 degrees F), respectively. The yield and ultimate strengths of both steel plate materials of the MHTGR Program increased with decreasing irradiation temperature. Similarly, the 41-J Charpy V-notch (CVN) transition temperature shift increased with decreasing irradiation temperature (in agreement with the increase in yield strength). The miniature tensile and automated ball indentation (ABI) test results (yield strength and flow properties) were in good agreement with those from standard tensile specimens. The miniature tensile and ABI test results were also used in a model that utilizes the changes in yield strength to estimate the CVN ductile-to-brittle transition temperature shift due to irradiation. The model predictions were compared with CVN test results obtained here and in earlier work. 5 refs., 11 figs., 6 tabs

  14. Post-giant evolution of helium stars

    International Nuclear Information System (INIS)

    Schoenberner, D.

    1977-01-01

    Extremely hydrogen deficient stars (helium stars and R Coronae Borealis variables) are considered to be remnants of double shell source stars (of the asymptotic giant branch). The evolution of stars with a condensed C/O-core and a helium envelope is followed numerically from the red giant stage to the white dwarf domain, crossing the regions of R CrB- and helium stars (so far analyzed). They have typically masses M/M(sun) = 0.7 and luminosities log L/L(sun) = 4.1. The time for crossing the helium star domain is some 10 3 years. The corresponding times in the R CrB-region amounts up to several 10 4 years. The lower limit of the death rate of helium stars is estimated to be 4 x 10 -14 pc -3 yr -1 . This value is only a factor of ten lower than the birth rate of all non-DA white dwarfs. It is therefore possible that the helium stars are the precursors of helium rich white dwarfs. As a consequence, a significant fraction of all stars which end their lives as white dwarfs should pass through the helium star phase. (orig.) [de

  15. RPC performance vs. front-end electronics

    International Nuclear Information System (INIS)

    Cardarelli, R.; Aielli, G.; Camarri, P.; Di Ciaccio, A.; Di Stante, L.; Liberti, B.; Pastori, E.; Santonico, R.; Zerbini, A.

    2012-01-01

    Moving the amplification from the gas to the front-end electronics was a milestone in the development of Resistive Plate Chambers. Here we discuss the historical evolution of RPCs and we show the results obtained with newly developed front-end electronics with threshold in the fC range.

  16. Molecular cloning and expression analyses of porcine MAP1LC3A in the granulosa cells of normal and miniature pig

    Directory of Open Access Journals (Sweden)

    Kim Sang H

    2013-02-01

    Full Text Available Abstract Background The members of the microtubule-associated protein 1 light chain (MAP1LC family, especially those of the LC3 family (MAP1LC3A, B, C, are known to induce autophagy upon localization onto the autophagosomal membrane. In this regard, LC3 can be utilized as a marker for the formation of autophagosomes during the process of autophagy. The aims of this study are to clone porcine MAP1LC3A, and analyze the pattern of its expression in the ovarian tissues of normal and miniature pig ovary in an attempt to understand the distinct mode of apoptosis between two strains. Methods Rapid amplification of cDNA ends (RACE were used to obtain the 5′ and 3′ ends of the porcine MAP1LC3A full length cDNA. Reverse-transcriptase-PCR (RT-PCR, real-time PCR, and western blot analysis were performed to examine the expression of porcine MAP1LC3A. The localization of MAP1LC3A in the ovary was determined by In situ Hybridization and Immunohistochemical staining. Results We cloned the full-length cDNA of porcine MAP1LC3A and identified an open reading frame of 980 bp encoding 121 amino acids. Based on its homology to known mammalian proteins (98% this novel cDNA was designated as porcine MAP1LC3A and registered to the GenBank (Accession No. GU272221. We compared the expression of MAP1LC3A in the Graafian follicles of normal and miniature pigs by in situ hybridization at day 15 of the estrus cycle. While normal pigs showed a stronger expression of MAP1LC3A mRNA than miniature pigs in the theca cell area, the expression was lower in the granulosa cells. Immunofluorescence analysis of the MAP1LC3A fusion reporter protein showed the subcellular localization of porcine MAP1LC3A and ATG5 as a punctate pattern in the cytoplasm of porcine granulosa cells under stress conditions. In addition, the expressions of MAP1LC3A and ATG5 were higher in normal pigs than in miniature pigs both in the presence and absence of rapamycin. Conclusions The newly cloned porcine

  17. Effect of Six Missile-Bay Baffle Configurations and a Rocket End Plate on Ejection Releases of an MB-1 Rocket from a 0.05 Scale Model of the Convair F-106A Airplane

    Science.gov (United States)

    Hinson, William F.; Lee, John B.

    1959-01-01

    As a continuation of an investigation of the release characteristics of an MB-1 rocket carried internally by the Convair F-106A airplane, six missile-bay baffle configurations and a rocket end plate have been investigated in the 27- by 27-inch preflight jet of the NASA Wallops Station. The MB-1 rocket used had retractable fins and was ejected from a missile bay modified by the addition of six different baffle configurations. For some tests a rocket end plate was added to the model. Dynamically scaled models (0.04956 scale) were tested at a simulated altitude of 22,450 feet and Mach numbers of 0.86, 1.59, and 1.98, and at a simulated altitude of 29,450 feet and a Mach number of 1.98. The results of this investigation indicate that the missile-bay baffle configurations and the rocket end plate may be used to reduce the positive pitch amplitude of the MB-1 rocket after release. The initial negative pitching velocity applied to the MB-1 rocket might then be reduced in order to maintain a near-level-flight attitude after release. As the fuselage angle of attack is increased, the negative pitch amplitude of the rocket is decreased.

  18. Research on Miniature Calibre Rail-Guns for the Mechanical Arm

    Directory of Open Access Journals (Sweden)

    Ronggang Cao

    2017-01-01

    Full Text Available Rail-gun should not only be used to military applications, but also can be developed as applications in the civilian aspects of the market. With the development of the electromagnetic launch technology, based on the similarity theory, using the existing rail-gun model to guide the construction of more economical miniature calibre rail-guns, and apply it in some machinery and equipment, this idea will open up a wider rail-gun application space. This article will focus on the feasibility of application of miniature calibre rail-guns in the mechanical arm. This paper designs the schematic diagram, then theoretical analyzes force conditions of the armature in the mechanical arm, calculates the possible range of the current amplitude and so on. The existing rail-gun model can be used to guides design the circuit diagram of the miniature calibre rail-gun. Based on the similarity theory and many simulation experiments, designed the experimental parameters of a miniature rail-gun and analyzed the current, Lorentz force, velocity, and location of the existing rail-gun and miniature rail-gun. The results show that the rail-gun launching technology applied to robot arms is feasibility. The application of miniature calibre rail-guns in the mechanical arm will benefit to the further development of rail-guns.

  19. Staged management of giant traumatic abdominal wall defect: A rare case report

    Directory of Open Access Journals (Sweden)

    Somendra Bansal

    2013-12-01

    Full Text Available Blunt traumatic abdominal wall disruptions associated with evisceration (abdominal wall injury grade type VI are very rare. We describe a case of large traumatic abdominal wall disruption with bowel evisceration and complete transection of jejunum and sigmoid colon that occurred after a 30-year-old male sustained run over injury to abdomen. Abdominal exploration and primary end to end jejuno-jejunal and colo-colic anastomosis were done. Staged management of giant abdominal wall defect was performed without any plastic reconstruction with good clinical outcome.

  20. Homozygosity of single nucleotide polymorphisms in the 3' region of the canine estrogen receptor 1 gene is greater in Toy Poodles than in Miniature Dachshunds and Chihuahuas.

    Science.gov (United States)

    Pathirana, Indunil N; Tanaka, Kakeru; Kawate, Noritoshi; Tsuji, Makoto; Hatoya, Shingo; Inaba, Toshio; Tamada, Hiromichi

    2011-06-01

    Differences in the distribution of single nucleotide polymorphisms (SNPs) and haplotypes in the estrogen receptor α gene (ESR1) were examined in Miniature Dachshunds (n = 48), Chihuahuas (n = 20) and Toy Poodles (n = 18). Five DNA fragments located in the 40-kb region at the 3' end of ESR1 were amplified by polymerase chain reaction and were directly sequenced. We compared allele, genotype and estimated haplotype frequencies at each SNP in the 3' end of ESR1 for these three breeds of small dog. The frequency of the major allele and the genotype frequency of the major allele homozygotes, were significantly higher in Toy Poodles for five SNPs (SNP #5, #14-17) than in Miniature Dachshunds, and significantly higher in Toy Poodles than Chihuahuas for three SNPs (SNP #15-17). A common haplotype block was identified in an approximately 20-kb region encompassing four SNPs (SNPs # 14-17). The frequencies of the most abundant estimated haplotype (GTTG) and GTTG homozygotes were significantly higher in Toy Poodles than in the other two breeds. These results imply that homozygosity for the allele, genotype and haplotype distribution within the block at the 3' end of ESR1 is greater in Toy Poodles than in Miniature Dachshunds and Chihuahuas. © 2011 The Authors; Animal Science Journal © 2011 Japanese Society of Animal Science.

  1. A Miniature Recording Cardiotachometer

    DEFF Research Database (Denmark)

    Zsombor-Murray, Paul J; Vroomen, Louis J.; Hendriksen, Nils Thedin

    1981-01-01

    The design of a miniature, recording cardiotachometer is described. It is simple and can store digital data. Bench and field tests, using a hand-held display, are presented. Construction and principles of operation are discussed. Applications, with performing athlete subjects, are outlined....

  2. Red giants: then and now

    Science.gov (United States)

    Faulkner, John

    sh·ρolinec prove to be important self-consistently derived quantities. I present some striking, explicit, asymptotic analytical theorems and results involving these quantities. Perhaps the most astonishingly unexpected and gratifying single result is this: for the very value Nature gives us for the relevant temperature exponent (η=15; CNO cycle) for nuclear-energy generation, ρsh and ρolinec behave in a well defined, precisely inverse manner for a given value of core-mass, Mc. This emphasizes that the internal behaviour of such stars is definitely anti-homologous rather than homologous: dense cores physically promote diffuse surrounding envelopes. I also extend the ideas yet further in a way which (I) links the structural and evolutionary behaviour of stars from the main sequence through horizontal-branch phases of evolution, and (II) also has implications for post-main-sequence developments in more massive stars. The end results is that the post-main-sequence developments of all stars - low-mass, intermediate-mass, and high-mass - as they expand to become giants, are finally seen to be examples of one underpinning fact: that dense cores with this surrounding shells naturally follow hydrogen exhaustion. While "this has been know all along" from oft-repeated computer calculations, we now know why analytically. That matters to true theorists. What follows is a requested, much expanded version of my Cambridge talk.

  3. Miniature Optical Isolator, Phase II

    Data.gov (United States)

    National Aeronautics and Space Administration — To address NASA's need for compact optical isolators, Physical Optics Corporation (POC) proposes to continue the development of a new Miniature Optical Isolator...

  4. Continuous flow nitration in miniaturized devices

    Directory of Open Access Journals (Sweden)

    Amol A. Kulkarni

    2014-02-01

    Full Text Available This review highlights the state of the art in the field of continuous flow nitration with miniaturized devices. Although nitration has been one of the oldest and most important unit reactions, the advent of miniaturized devices has paved the way for new opportunities to reconsider the conventional approach for exothermic and selectivity sensitive nitration reactions. Four different approaches to flow nitration with microreactors are presented herein and discussed in view of their advantages, limitations and applicability of the information towards scale-up. Selected recent patents that disclose scale-up methodologies for continuous flow nitration are also briefly reviewed.

  5. Goniometry and Limb Girth in Miniature Dachshunds

    Directory of Open Access Journals (Sweden)

    Stephanie A. Thomovsky

    2016-01-01

    Full Text Available Purpose. To report the mean and median pelvic limb joint angles and girth measurements in miniature Dachshunds presenting with varying degrees of pelvic limb weakness secondary to thoracolumbar intervertebral disc extrusion. Methods. 15 miniature Dachshunds who presented to WSU-VTH for thoracolumbar disc extrusion. Dachshunds varied in neurologic status from ambulatory paraparetic to paraplegic at the time of measurements. Results. There were no significant differences in joint angles or girth among the three groups (ambulatory paraparetic, nonambulatory paraparetic, or paraplegic (P>0.05. When group was disregarded and values for extension, flexion, and girth combined, no differences existed. Conclusions. Goniometry and limb girth measurements can successfully be made in the miniature Dachshund; however, the shape of the Dachshund leg makes obtaining these values challenging. There were no differences in joint angle or girth measurements between dogs with varying neurologic dysfunction at the time of measurement.

  6. Goniometry and Limb Girth in Miniature Dachshunds.

    Science.gov (United States)

    Thomovsky, Stephanie A; Chen, Annie V; Kiszonas, Alecia M; Lutskas, Lori A

    2016-01-01

    Purpose. To report the mean and median pelvic limb joint angles and girth measurements in miniature Dachshunds presenting with varying degrees of pelvic limb weakness secondary to thoracolumbar intervertebral disc extrusion. Methods. 15 miniature Dachshunds who presented to WSU-VTH for thoracolumbar disc extrusion. Dachshunds varied in neurologic status from ambulatory paraparetic to paraplegic at the time of measurements. Results. There were no significant differences in joint angles or girth among the three groups (ambulatory paraparetic, nonambulatory paraparetic, or paraplegic) (P > 0.05). When group was disregarded and values for extension, flexion, and girth combined, no differences existed. Conclusions. Goniometry and limb girth measurements can successfully be made in the miniature Dachshund; however, the shape of the Dachshund leg makes obtaining these values challenging. There were no differences in joint angle or girth measurements between dogs with varying neurologic dysfunction at the time of measurement.

  7. Superstorms at the end of the Last Interglacial (MIS 5e)? Modeling paleo waves and the transport of giant boulders.

    Science.gov (United States)

    Rovere, Alessio; Harris, Daniel; Casella, Elisa; Lorscheid, Thomas; Stocchi, Paolo; Nandasena, Napayalage; Sandstrom, Michael; D'Andrea, William; Dyer, Blake; Raymo, Maureen

    2017-04-01

    We present the results of high-resolution field surveys and wave models along the cliffs of the northern part of the Island of Eleuthera, Bahamas. Previous studies have proposed that cliff top mega-boulders were emplaced at the end of the Last Interglacial (MIS 5e, 128-116 ka) by giant swells caused by super-storms that find no counterpart in the Holocene (including historical times). Our results suggest that these boulders could have instead been transported from the cliff face to the top of the cliff by a storm analogous to the 1991 'Perfect Storm', if sea level during MIS 5e sea was more than 4 meters higher than today. We remark that the data-model approach used here is essential to interpreting the geologic evidence of extreme storms during past warm periods, which in turn, is an important tool for predicting the intensity of extreme storm events in future climates. Our results indicate that even without an increase in storm intensity, cliffs and hard coastal barriers might be subject to significant increases wave-generated stresses under conditions of sea levels modestly higher than present.

  8. Pricing of miniature vehicles made from telephone card waste

    Science.gov (United States)

    Puspitasari, N. B.; Pujotomo, D.; Muhardiansyah, H.

    2017-12-01

    The number of electronic devices in Indonesia in the last 10 years has been increasing quite drastically which contributes to more electronic waste. E-waste or electronic waste have different characteristics from other kinds of waste. Components of electronic waste often poisonous, consisting dangerous chemicals. The telephone card wasted is also an electronic waste. One alternative to handle and manage telephone card waste is to recycle it into collectible miniature vehicles. But the price of these miniatures is quite high, causing low interest in buying them. A research on the price of miniature vehicles in relation to consumers’ Ability to Pay (ATP) and Willingness to Pay (WTP) needs to be done. Segmentation analysis data, target, product positioning and product marketing mix are needed before commencing the research. Data collection is done through a survey by spreading questionnaire to 100 miniature vehicle collectors in Semarang, questioning their ability and willingness to pay recycled miniature vehicles. Calculations showed average ATP of Rp.112.520, 24 and average WTP of Rp.76.870. The last result showed the estimate pricing according to ATP and WTP which is Rp.66.000 with 58% of the respondents claiming to be willing and able to pay that price.

  9. Miniature UAVs : An overview

    NARCIS (Netherlands)

    Weimar, P.W.L.; Kerkkamp, J.S.F.; Wiel, R.A.N.; Meiller, P.P.; Bos, J.G.H.

    2014-01-01

    With this book TNO provides an overview of topics related to Miniature Unmanned Aerial Vehicles (MUAVs). Both novices and experts may find this publication valuable. The Netherlands Organisation for Applied Scientific Research TNO conducts research on UAVs and MUAVs, see for example [1], on the

  10. A Decade of Giant Earthquakes - What does it mean?

    Energy Technology Data Exchange (ETDEWEB)

    Wallace, Terry C. Jr. [Los Alamos National Laboratory

    2012-07-16

    On December 26, 2004 the largest earthquake since 1964 occurred near Ache, Indonesia. The magnitude 9.2 earthquake and subsequent tsunami killed a quarter of million people; it also marked the being of a period of extraordinary seismicity. Since the Ache earthquake there have been 16 magnitude 8 earthquakes globally, including 2 this last April. For the 100 years previous to 2004 there was an average of 1 magnitude 8 earthquake every 2.2 years; since 2004 there has been 2 per year. Since magnitude 8 earthquakes dominate global seismic energy release, this period of seismicity has seismologist rethinking what they understand about plate tectonics and the connectivity between giant earthquakes. This talk will explore this remarkable period of time and its possible implications.

  11. Differential rotation and giant cell circulation of the solar Ca+-network

    International Nuclear Information System (INIS)

    Schroeter, E.H.; Woehl, H.

    1976-01-01

    High precision computer controlled tracings of bright Ca + -mottles were performed during 1974 and 1975 at the Locarno Observatory of Gottingen to study solar differential rotation and to search for giant cell circulation pattern. The method consists of measuring the position of 5-15 bright Ca + - mottles with respect to the center of the solar disc every 10 to 15 min during 4h every day. From a linear least square fit of the observed positions the solar-latitude and longitude were computed for the beginning and the end of the daily 4h observation period. From this the components in latitude and longitude of the proper motions were derived which result from the differential rotation, possible giant cell circulation and the small scale random walk of these features. (Auth.)

  12. Microwave Photonic Architecture for Direction Finding of LPI Emitters: Front End Analog Circuit Design and Component Characterization

    Science.gov (United States)

    2016-09-01

    into two parts. The design, development, and testing efforts of the front-end microwave photonics circuit design and the system integration with the...miniature microwave - photonic phase-sampling DF technique is investigated in this thesis. This front-end design uses a combination of integrated optical...NAVAL POSTGRADUATE SCHOOL MONTEREY, CALIFORNIA THESIS Approved for public release. Distribution is unlimited. MICROWAVE

  13. Irradiation of full size UMo plates

    International Nuclear Information System (INIS)

    Vacelet, H.; Lavastre, Y.; Grasse, M.; Sacristan, P.; Languille, A.

    1999-01-01

    An important development program for a UMo MTR fuel has been launched in France. The goal of the French working group is to develop a high performing and reprocessable fuel before the end of the US return policy. This paper is focussed on the fabrication of full-sized UMo plates with LEU (Low Enriched Enrichment) and their irradiation in OSIRIS reactor which was started on the 22nd of September. The results of the plates inspection are presented here as well as the irradiation conditions. (author)

  14. Biosynthesis of fatty acids and cholesterol in squid giant nerve fiber

    International Nuclear Information System (INIS)

    Tanaka, T.; Kishimoto, Y.; Gould, R.M.

    1987-01-01

    The giant nerve fiber of squid 3 (loligo pealel) was incubated with [1- 14 C]acetate and ( 3 H)myristate. Fifty-five percent of the radioactivity incorporated from acetate was recovered in fatty acid methyl esters (FAME). The FAME was fractionated by AgNO 3 -impregnated TLC plate; and 52%, 31%, 0.3%, 5%, and 11% of the radioactivity was recovered in spots associated with saturated, monoenes, dienes, trienes, and polyenes, respectively. The saturated FAME was further fractionated by reverse-phase HPLC; and 4, 47, 1, and 48% of the radioactivity was recovered in 14:0, 16:0, 17:0, and 18:0, respectively. Most radioactivity from polyenes migrated to the spot containing saturated FAME, after catalytical hydrogenation. Cholesterol was isolated and converted to dibromoderivative and the derivative was recrystallized. No radioactivity was found in purified dibromocholesterol. Nearly all radioactivity from myristate-labeled tissue was recovered in saturated FAME. Reverse-phase HPLC showed that 71%, 25%, and 3% of radioactivity was associated with 14:0, 16:0, and 18:0, respectively. These results indicate that the squid giant nerve fibers can synthesize fatty acids by de novo and also by chain elongation and desaturation, though at a slower rate

  15. Femtosecond laser-assisted cataract surgery and implantable miniature telescope

    Directory of Open Access Journals (Sweden)

    Randal Pham

    2017-09-01

    Conclusions and importance: To our knowledge and confirmed by the manufacturer of the implantable miniature telescope this is the first case ever reported of a patient who has undergone femtosecond laser cataract surgery with corneal astigmatism correction and implantation of the implantable miniature telescope. This is also the first case report of the preoperative use of microperimetry and visual electrophysiology to evaluate a patient's postoperative potential visual acuity. The success of the procedure illustrated the importance of meticulous preoperative planning, the combined use of state-of-the-art technologies and the seamless teamwork in order to achieve the best clinical outcome for patients who undergo implantation of the implantable miniature telescope.

  16. Miniaturized module for the wireless transmission of measurements with Bluetooth.

    Science.gov (United States)

    Roth, H; Schwaibold, M; Moor, C; Schöchlin, J; Bolz, A

    2002-01-01

    The wiring of patients for obtaining medical measurements has many disadvantages. In order to limit these, a miniaturized module was developed which digitalizes analog signals and sends the signal wirelessly to the receiver using Bluetooth. Bluetooth is especially suitable for this application because distances of up to 10 m are possible with low power consumption and robust transmission with encryption. The module consists of a Bluetooth chip, which is initialized in such a way by a microcontroller that connections from other bluetooth receivers can be accepted. The signals are then transmitted to the distant end. The maximum bit rate of the 23 mm x 30 mm module is 73.5 kBit/s. At 4.7 kBit/s, the current consumption is 12 mA.

  17. Inner Super-Earths, Outer Gas Giants: How Pebble Isolation and Migration Feedback Keep Jupiters Cold

    Science.gov (United States)

    Fung, Jeffrey; Lee, Eve J.

    2018-06-01

    The majority of gas giants (planets of masses ≳102 M ⊕) are found to reside at distances beyond ∼1 au from their host stars. Within 1 au, the planetary population is dominated by super-Earths of 2–20 M ⊕. We show that this dichotomy between inner super-Earths and outer gas giants can be naturally explained should they form in nearly inviscid disks. In laminar disks, a planet can more easily repel disk gas away from its orbit. The feedback torque from the pile-up of gas inside the planet’s orbit slows down and eventually halts migration. A pressure bump outside the planet’s orbit traps pebbles and solids, starving the core. Gas giants are born cold and stay cold: more massive cores are preferentially formed at larger distances, and they barely migrate under disk feedback. We demonstrate this using two-dimensional hydrodynamical simulations of disk–planet interaction lasting up to 105 years: we track planet migration and pebble accretion until both come to an end by disk feedback. Whether cores undergo runaway gas accretion to become gas giants or not is determined by computing one-dimensional gas accretion models. Our simulations show that in an inviscid minimum mass solar nebula, gas giants do not form inside ∼0.5 au, nor can they migrate there while the disk is present. We also explore the dependence on disk mass and find that gas giants form further out in less massive disks.

  18. Lamb wave extraction of dispersion curves in micro/nano-plates using couple stress theories

    Science.gov (United States)

    Ghodrati, Behnam; Yaghootian, Amin; Ghanbar Zadeh, Afshin; Mohammad-Sedighi, Hamid

    2018-01-01

    In this paper, Lamb wave propagation in a homogeneous and isotropic non-classical micro/nano-plates is investigated. To consider the effect of material microstructure on the wave propagation, three size-dependent models namely indeterminate-, modified- and consistent couple stress theories are used to extract the dispersion equations. In the mentioned theories, a parameter called 'characteristic length' is used to consider the size of material microstructure in the governing equations. To generalize the parametric studies and examine the effect of thickness, propagation wavelength, and characteristic length on the behavior of miniature plate structures, the governing equations are nondimensionalized by defining appropriate dimensionless parameters. Then the dispersion curves for phase and group velocities are plotted in terms of a wide frequency-thickness range to study the lamb waves propagation considering microstructure effects in very high frequencies. According to the illustrated results, it was observed that the couple stress theories in the Cosserat type material predict more rigidity than the classical theory; so that in a plate with constant thickness, by increasing the thickness to characteristic length ratio, the results approach to the classical theory, and by reducing this ratio, wave propagation speed in the plate is significantly increased. In addition, it is demonstrated that for high-frequency Lamb waves, it converges to dispersive Rayleigh wave velocity.

  19. Gradual Changes of Gut Microbiota in Weaned Miniature Piglets

    Directory of Open Access Journals (Sweden)

    Xianghua Yan

    2016-11-01

    Full Text Available Colonization of gut microbiota in mammals during the early life is vital to host health. The miniature piglet has recently been considered as an optimal infant model. However, less is known about the development of gut microbiota in miniature piglets. Here, this study was conducted to explore how the gut microbiota develops in weaned Congjiang miniature piglets. In contrast to the relatively stabilized gut fungal community, gut bacterial community showed a marked drop in alpha diversity, accompanied by significant alterations in taxonomic compositions. The relative abundances of 24 bacterial genera significantly declined, whereas the relative abundances of 7 bacterial genera (Fibrobacter, Collinsella, Roseburia, Prevotella, Dorea, Howardella, and Blautia significantly increased with the age of weaned piglets. Fungal taxonomic analysis showed that the relative abundances of 2 genera (Kazachstania and Aureobasidium significantly decreased, whereas the relative abundances of 4 genera (Aspergillus, Cladosporium, Simplicillium, and Candida significantly increased as the piglets aged. Kazachstania telluris was the signature species predominated in gut fungal communities of weaned miniature piglets. The functional maturation of the gut bacterial community was characterized by the significantly increased digestive system, glycan biosynthesis and metabolism, and vitamin B biosynthesis as the piglets aged. These findings suggest that marked gut microbial changes in Congjiang miniature piglets may contribute to understand the potential gut microbiota development of weaned infants.

  20. Miniature, Single Channel, Memory-Based, High-G Acceleration Recorder (Millipen)

    International Nuclear Information System (INIS)

    Rohwer, Tedd A.

    1999-01-01

    The Instrumentation and Telemetry Departments at Sandia National Laboratories have been instrumenting earth penetrators for over thirty years. Recorded acceleration data is used to quantify penetrator performance. Penetrator testing has become more difficult as desired impact velocities have increased. This results in the need for small-scale test vehicles and miniature instrumentation. A miniature recorder will allow penetrator diameters to significantly decrease, opening the window of testable parameters. Full-scale test vehicles will also benefit from miniature recorders by using a less intrusive system to instrument internal arming, fusing, and firing components. This single channel concept is the latest design in an ongoing effort to miniaturize the size and reduce the power requirement of acceleration instrumentation. A micro-controller/memory based system provides the data acquisition, signal conditioning, power regulation, and data storage. This architecture allows the recorder, including both sensor and electronics, to occupy a volume of less than 1.5 cubic inches, draw less than 200mW of power, and record 15kHz data up to 40,000 gs. This paper will describe the development and operation of this miniature acceleration recorder

  1. Giant pulses of pulsar radio emission

    OpenAIRE

    Kuzmin, A. D.

    2007-01-01

    Review report of giant pulses of pulsar radio emission, based on our detections of four new pulsars with giant pulses, and the comparative analysis of the previously known pulsars with giant pulses, including the Crab pulsar and millisecond pulsar PSR B1937+21.

  2. A miniature fiber-optic temperature sensor based on a Fabry–Perot interferometer

    International Nuclear Information System (INIS)

    Rong, Qiangzhou; Sun, Hao; Qiao, Xueguang; Zhang, Jing; Hu, Manli; Feng, Zhongyao

    2012-01-01

    A miniature fiber Fabry–Perot interferometer (FFPI) for temperature measurement is proposed and demonstrated. The sensor consists of a section of single-mode fiber (SMF) tip coated with a thin film of polyvinyl alcohol (PVA) at the end of the fiber tip. A well-defined interference pattern is obtained as the result of the FFPI based on Fresnel reflection. The sensing head is extremely sensitive to ambient temperature, and provides a stable temperature sensitivity with a maximum value up to 173.5 pm °C −1 above 80 °C. This proposed sensor has advantages of low cost, ultra-compactness, a small degree of hysteresis and high stability. (paper)

  3. The Textile Elements in Ottoman Miniatures

    Directory of Open Access Journals (Sweden)

    Kevser Gürcan Y A R D I M C I

    2015-07-01

    Full Text Available With the value given to the art and the artist, high quality works of art in many fields were produced in the Ottoman Era. The art of weaving also lived its brightest period in terms of color, design, and weaving techniques in the Ottoman Empire in XVI. Ce ntury. The weaving products shaped the lifestyles of the people in those times and received great interest in the Palace as well. Silk woven fabrics had become such a great power in those times that it became the greatest symbol showing the power of the Ot toman Empire to the foreigners, and the determiner of the social standing within the society. The Ottoman Sultans used their clothing, which they made to become flamboyant with embroideries, to distinguish themselves from the public, and make them accept t heir power. Among the presents that were presented to the Sultans, clothes, kaftans, and similar fabrics as well as other precious presents, were frequent. The miniature manuscripts that were produced in the Palace are in the quality of unique documents t hat transfer yesterday’s knowledge to the modern age. It is easy to decode the dimensions of the clothing habits, decoration elements and hierarchy concepts of the Ottoman Era, as well as the weaving activities by using the miniature manuscripts. On the ot her hand, these elements constitute a rich alphabet in transferring the emotional structure of the society in those times, the traditions and habits to our world today. The greatest share in this effort belongs to the artists who depicted the miniatures by staying loyal to the texts in the manuscripts as well as to their active participation in the events of those times and their narrating the events as the very first observers. In addition, the muralists depicting the manuscripts and their undertaking the job of drawing the designs on the original fabric helped them to reflect the richness in the design of those times to the miniatures. In this study, the weavings and the accessories

  4. Miniaturized nuclear battery

    International Nuclear Information System (INIS)

    Adler, K.; Ducommun, G.

    1976-01-01

    The invention relates to a miniaturized nuclear battery, consisting of several in series connected cells, wherein each cell contains a support which acts as positive pole and which supports on one side a β-emitter, above said emitter is a radiation resisting insulation layer which is covered by an absorption layer, above which is a collector layer, and wherein the in series connected calls are disposed in an airtight case

  5. Variable recruitment in bundles of miniature pneumatic artificial muscles.

    Science.gov (United States)

    DeLaHunt, Sylvie A; Pillsbury, Thomas E; Wereley, Norman M

    2016-09-13

    The natural compliance and force generation properties of pneumatic artificial muscles (PAMs) allow them to operate like human muscles in anthropomorphic robotic manipulators. Traditionally, manipulators use a single PAM or multiple PAMs actuated in unison in place of a human muscle. However, these standard manipulators can experience significant efficiency losses when operated outside their target performance ranges at low actuation pressures. This study considers the application of a variable recruitment control strategy to a parallel bundle of miniature PAMs as an attempt to mimic the selective recruitment of motor units in a human muscle. Bundles of miniature PAMs are experimentally characterized, their actuation behavior is modeled, and the efficiency gains and losses associated with the application of a variable recruitment control strategy are assessed. This bio-inspired control strategy allows muscle bundles to operate the fewest miniature PAMs necessary to achieve a desired performance objective, improving the muscle bundle's operating efficiency over larger ranges of force generation and displacement. The study also highlights the need for improved PAM fabrication techniques to facilitate the production of identical miniature PAMs for inclusion in muscle bundles.

  6. Giant Oil Fields - The Highway to Oil: Giant Oil Fields and their Importance for Future Oil Production

    International Nuclear Information System (INIS)

    Robelius, Fredrik

    2007-01-01

    Since the 1950s, oil has been the dominant source of energy in the world. The cheap supply of oil has been the engine for economic growth in the western world. Since future oil demand is expected to increase, the question to what extent future production will be available is important. The belief in a soon peak production of oil is fueled by increasing oil prices. However, the reliability of the oil price as a single parameter can be questioned, as earlier times of high prices have occurred without having anything to do with a lack of oil. Instead, giant oil fields, the largest oil fields in the world, can be used as a parameter. A giant oil field contains at least 500 million barrels of recoverable oil. Only 507, or 1 % of the total number of fields, are giants. Their contribution is striking: over 60 % of the 2005 production and about 65 % of the global ultimate recoverable reserve (URR). However, giant fields are something of the past since a majority of the largest giant fields are over 50 years old and the discovery trend of less giant fields with smaller volumes is clear. A large number of the largest giant fields are found in the countries surrounding the Persian Gulf. The domination of giant fields in global oil production confirms a concept where they govern future production. A model, based on past annual production and URR, has been developed to forecast future production from giant fields. The results, in combination with forecasts on new field developments, heavy oil and oil sand, are used to predict future oil production. In all scenarios, peak oil occurs at about the same time as the giant fields peak. The worst-case scenario sees a peak in 2008 and the best-case scenario, following a 1.4 % demand growth, peaks in 2018

  7. Miniature Blimps for Surveillance and Collection of Samples

    Science.gov (United States)

    Jones, Jack

    2004-01-01

    Miniature blimps are under development as robots for use in exploring the thick, cold, nitrogen atmosphere of Saturn's moon, Titan. Similar blimps can also be used for surveillance and collection of biochemical samples in buildings, caves, subways, and other, similar structures on Earth. The widely perceived need for means to thwart attacks on buildings and to mitigate the effects of such attacks has prompted consideration of the use of robots. Relative to rover-type (wheeled) robots that have been considered for such uses, miniature blimps offer the advantage of ability to move through the air in any direction and, hence, to perform tasks that are difficult or impossible for wheeled robots, including climbing stairs and looking through windows. In addition, miniature blimps are expected to have greater range and to cost less, relative to wheeled robots.

  8. Miniature scientific-grade induction magnetometer for cubesats

    Science.gov (United States)

    Pronenko, Vira

    2017-04-01

    One of the main areas of space research is the study and forecasting of space weather. The society is more and more depending nowadays on satellite technology and communications, so it is vital to understand the physical process in the solar-terrestrial system which may disturb them. Besides the solar radiation and Space Weather effects, the Earth's ionosphere is also modified by the ever increasing industrial activity. There have been also multiple reports relating VLF and ELF wave activity to atmospheric storms and geological processes, such as earthquakes and volcanic activity. For advancing in these fields, the AC magnetic field permanent monitoring is crucial. Using the cubesat technology would allow increasing the number of measuring points dramatically. It is necessary to mention that the cubesats use for scientific research requires the miniaturization of scientific sensors what is a serious problem because the reduction of their dimensions leads, as a rule, to the parameters degradation, especially of sensitivity threshold. Today, there is no basic model of a sensitive miniature induction magnetometer. Even the smallest one of the known - for the Bepi-Colombo mission to Mercury - is too big for cubesats. The goal of the present report is to introduce the new design of miniature three-component sensor for measurement of alternative vector magnetic fields - induction magnetometer (IM). The study directions were concentrated on the ways and possibilities to create the miniature magnetometer with best combination of parameters. For this a set of scientific and technological problems, mostly aimed at the sensor construction improvement, was solved. The most important parameter characterizing magnetometer quality is its own magnetic noise level (NL). The analysis of the NL influencing factors is made and the ways to decrease it are discussed in the report. Finally, the LEMI-151 IM was developed for the SEAM cubesat mission with optimal performances within the

  9. NINO An ultra-fast and low-power front-end amplifier/discriminator ASIC designed for the multigap resistive plate chamber

    CERN Document Server

    Anghinolfi, F; Martemyanov, A N; Usenko, E; Wenninger, Horst; Williams, M C S; Zichichi, A

    2004-01-01

    For the full exploitation of the excellent timing properties of the Multigap Resistive Plate Chamber (MRPC), front-end electronics with special characteristics are needed. These are (a) differential input, to profit from the differential signal from the MRPC (b) a fast amplifier with less than 1 ns peaking time and (c) input charge measurement by Time-Over-Threshold for slewing correction. An 8- channel amplifier and discriminator chip has been developed to match these requirements. This is the NINO ASIC, fabricated with 0.25 omegam CMOS technology. The power requirement at 40mW/channel is low. Results on the performance of the MRPCs using the NINO ASIC are presented. Typical time resolution a of the MRPC system is in the 50 ps range, with an efficiency of 99.9%.

  10. Miniature Ground Mapping LADAR, Phase I

    Data.gov (United States)

    National Aeronautics and Space Administration — System & Processes Engineering Corporation (SPEC) proposes a miniature solid state surface imaging LADAR, for imaging the landing areas providing precision...

  11. Autonomous stair-climbing with miniature jumping robots.

    Science.gov (United States)

    Stoeter, Sascha A; Papanikolopoulos, Nikolaos

    2005-04-01

    The problem of vision-guided control of miniature mobile robots is investigated. Untethered mobile robots with small physical dimensions of around 10 cm or less do not permit powerful onboard computers because of size and power constraints. These challenges have, in the past, reduced the functionality of such devices to that of a complex remote control vehicle with fancy sensors. With the help of a computationally more powerful entity such as a larger companion robot, the control loop can be closed. Using the miniature robot's video transmission or that of an observer to localize it in the world, control commands can be computed and relayed to the inept robot. The result is a system that exhibits autonomous capabilities. The framework presented here solves the problem of climbing stairs with the miniature Scout robot. The robot's unique locomotion mode, the jump, is employed to hop one step at a time. Methods for externally tracking the Scout are developed. A large number of real-world experiments are conducted and the results discussed.

  12. Excitation of giant resonances in heavy ion collisions

    International Nuclear Information System (INIS)

    Kuehn, W.

    1991-01-01

    Introduction: What are Giant Resonances? General Features of Giant Resonances, Macroscopic Description and Classification, Basic Excitation Mechanisms, Decay Modes, Giant Resonances Built on Excited States, Relativistic Coulomb Excitation of Giant Resonances, Experimental Situation. (orig.)

  13. Floret-like multinucleated giant cells in neurofibroma

    Directory of Open Access Journals (Sweden)

    Golka Dariusz

    2007-12-01

    Full Text Available Abstract This short report discusses a case of neurofibroma containing floret-like multinucleated giant cells. This being the second such case in the literature. Floret-like multinucleated giant cells have been reported in gynaecomastia and neurofibroma in neurofibromatosis type 1. These cells have been reported in uncommon soft tissue tumours including pleomorphic lipoma, giant cell collagenoma, giant cell fibroblastoma and giant cell angiofibroma. We recommend these cells to be interpreted carefully keeping in mind the rare malignant change in neurofibromas. Immunohistochemistry would help in defining the nature of such cells.

  14. Central Hypothyroidism in Miniature Schnauzers

    NARCIS (Netherlands)

    Voorbij, Annemarie M W Y; Leegwater, Peter A J; Buijtels, Jenny J C W M; Daminet, Sylvie; Kooistra, Hans S

    2016-01-01

    BACKGROUND: Primary hypothyroidism is a common endocrinopathy in dogs. In contrast, central hypothyroidism is rare in this species. OBJECTIVES: The objective of this article is to describe the occurrence and clinical presentation of central hypothyroidism in Miniature Schnauzers. Additionally, the

  15. Measurement of charge collection in irradiated miniature sensors for the upgrade of ATLAS Phase-II Strip tracker

    CERN Document Server

    Cindro, Vladimir; The ATLAS collaboration

    2018-01-01

    Miniature sensors with outer dimension of 10 mm x 10 mm were produced together with full size sensors for the innermost ring (R0) of the end-cap part in the upgraded ATLAS inner tracker (ITk). AC and DC coupled n-type strips with three different pitches (wide, default and narrow) were processed on high resistivity p-type FZ silicon substrates by Hamamatsu Photonics. Miniature sensors were irradiated with 70 MeV protons at CYRIC at Tohoku University (Japan) and reactor neutrons at Jožef Stefan Institute (Slovenia) to three different 1 MeV neutron equivalent fluences: 0.5, 1 and 2 x 1015 neqcm-2. The upper fluence range exceeds the highest anticipated in the inner-most part of the ATLAS ITk-Strips over the HL-LHC lifetime (~1.25 x 1015 neqcm2). Charge collection in test sensors has been evaluated systematically using 90Sr β- source and Alibava analogue readout system at reverse bias voltages up to 1000 V.

  16. Measurement of charge collection in irradiated miniature sensors for the upgrade of ATLAS Phase-II Strip tracker

    CERN Document Server

    Cindro, Vladimir; The ATLAS collaboration

    2017-01-01

    Miniature sensors with outer dimension of 10 mm x 10 mm have been produced together with full size sensors for the innermost ring (R0) of the end-cap part in the upgraded ATLAS inner tracker (ITk). AC and DC coupled n-type strips with three different pitches (wide, default and narrow) were processed on high resistivity p-type FZ silicon substrates by Hamamatsu Photonics. Miniature sensors were irradiated with 70 MeV protons at CYRIC at Tohoku University (Japan) and reactor neutrons at Jožef Stefan Institute (Slovenia) to three different 1 MeV neutron equivalent fluences: 0.5, 1 and 2 x 1015 neqcm-2. The upper fluence range exceeds the highest anticipated in the inner-most part of the ATLAS ITk-Strips over the HL-LHC lifetime (~1.5 x 1015 neqcm2). Charge collection in test sensors has been evaluated systematically using 90Sr β-source and Alibava analogue readout system at reverse bias voltages up to 1000 V.

  17. Small is beautiful: features of the smallest insects and limits to miniaturization.

    Science.gov (United States)

    Polilov, Alexey A

    2015-01-07

    Miniaturization leads to considerable reorganization of structures in insects, affecting almost all organs and tissues. In the smallest insects, comparable in size to unicellular organisms, modifications arise not only at the level of organs, but also at the cellular level. Miniaturization is accompanied by allometric changes in many organ systems. The consequences of miniaturization displayed by different insect taxa include both common and unique changes. Because the smallest insects are among the smallest metazoans and have the most complex organization among organisms of the same size, their peculiar structural features and the factors that limit their miniaturization are of considerable theoretical interest to general biology.

  18. A study for the improvement of top end piece structure strength

    International Nuclear Information System (INIS)

    Song, Kee Nam; Sohn, Dong Seong

    1989-01-01

    As a part of the top end piece(TEP) for the 14 X 14 reload fuel, various models of top end piece structure were analysed, using the ANSYS code, under fuel assembly shipping and handling load conditions. The 3-dimensional isoparametric elements were used in each model. By rearrangement of slots and holes on the adapter plate, without violating the design requirements, and also by changing the enclosure attachment method used on the adapter plate from pin joints to through-weld, the load carrying capacity of the adapter plate was greatly strengthened. These concepts were adopted for the design of the 14 X 14 reload fuel. (Author)

  19. Nanodielectrics with giant permittivity

    Indian Academy of Sciences (India)

    Following the prediction, during the last couple of years we have investigated the effect of giant permittivity in one-dimensional systems of conventional metals and conjugated polymer chains. In this article, we have tried to summarize the works on giant permittivity and finally the fabrication of nanocapacitor using metal ...

  20. From red giants to planetary nebulae

    International Nuclear Information System (INIS)

    Kwok, S.

    1982-01-01

    The transition from red giants to planetary nebulae is studied by comparing the spectral characteristics of red giant envelopes and planetary nebulae. Observational and theoretical evidence both suggest that remnants of red giant envelopes may still be present in planetary nebula systems and should have significant effects on their formation. The dynamical effects of the interaction of stellar winds from central stars of planetary nebulae with the remnant red giant envelopes are evaluated and the mechanism found to be capable of producing the observed masses and momenta of planetary nebulae. The observed mass-radii relation of planetary nebulae may also be best explained by the interacting winds model. The possibility that red giant mass loss, and therefore the production of planetary nebulae, is different between Population I and II systems is also discussed

  1. Structure Design and Performance Analysis of High-Speed Miniature Ball Bearing

    Science.gov (United States)

    Li, Songsheng; Zhang, Guoye; Chen, Bin; Shen, Yuan

    2017-07-01

    The working performances of miniature ball bearings are obviously affected by its’ geometric structure parameters. In this paper, quasi-static analysis theory is applied in the design of miniature ball bearings. Firstly, it is studied the influence of geometry structure, preload and rotating speed on the dynamic performance of bearing. Secondly, bearing dynamic characteristics are analyzed which include the bearing stiffness and Spin to roll Ratio. Lastly, the contact stress and bearing life are calculated. The results indicate that structure parameters play an importance role in bearing’s dynamic performances. Miniature ball bearings which have lager ball number, bigger ball diameter and smaller inner race groove radius can get better performances while velocity and preload have great impact on the bearing life. So that parameters of miniature bearing should be chosen cautiously.

  2. Using Miniature Landforms in Teaching Geomorphology.

    Science.gov (United States)

    Petersen, James F.

    1986-01-01

    This paper explores the uses of true landform miniatures and small-scale analogues and suggests ways to teach geomorphological concepts using small-scale relief features as illustrative examples. (JDH)

  3. Miniaturization of Multiple-Layer Folded Patch Antennas

    DEFF Research Database (Denmark)

    Zhang, Jiaying; Breinbjerg, Olav

    2009-01-01

    A new folded patch antenna with multiple layers was developed in this paper, by folding the patch in a proper way, and a highly miniaturized antenna can be realized. The multiple layer patch with 4-layer and 6-layer are designed and evaluated at 2.4 GHz, 915 MHz, and 415 MHz respectively. Then a 4...... layer patch is fabricated and measured to validate the design method. The theoretical analysis, design and simulations, fabrications, as well as the measurements are presented in this paper. All the results show that the folded patch antenna is a good candidate in making a highly miniaturized compact...

  4. Use of miniature tensile specimen and video extensometer for measurement of mechanical properties

    International Nuclear Information System (INIS)

    Kumar, Kundan; Pooleery, Arun; Madhusoodanan, K.

    2014-08-01

    Miniaturisation of the tensile test specimen below the sub-size level poses various challenges, such as conformity of specimen to various acceptance criteria as per standard test specimen, aspect ratio, minimum number of grains required in a gauge cross-section, fabrication for uniformity in metrological values, etc. Apart from these, measurement of strain over a very limited available space on the test specimen is another practical challenge. Despite these limitations, miniature specimen testing is increasingly being used worldwide these days. The driving forces behind increasing use of miniature test techniques are new material development, assuring fitness of component after in-service-inspection, low dose of radiation exposure due to smaller dimensions of test specimens etc. However, the evaluation of mechanical properties from a miniature tensile test has a greater advantage over the other miniature novel test techniques, such as small punch test, ABI, miniature fatigue and impact tests etc., as it is a direct method of measurement of mechanical properties. This report covers various aspects of miniature tensile test methodologies, which include geometrical design of specimen having gauge length of 3-5 mm, fabrication, development of special fixtures for gripping the test specimens, and use of optical method for strain measurement. The geometrical design of the specimen and its behaviour over application of tensile load has been established using FEM analysis. A good agreement between conventional and miniature test results exemplifies the potential of the miniature tensile test technique. (author)

  5. Preface Miniaturization and Mass Spectrometry

    NARCIS (Netherlands)

    Unknown, [Unknown; le Gac, Severine; le Gac, S.; van den Berg, Albert; van den Berg, A.

    2009-01-01

    Miniaturization and Mass Spectrometry illustrates this trend and focuses on one particular analysis technique, mass spectrometry whose popularity has "dramatically" increased in the last two decades with the explosion of the field of biological analysis and the development of two "soft" ionization

  6. Optimal Design, Reliability And Sensitivity Analysis Of Foundation Plate

    Directory of Open Access Journals (Sweden)

    Tvrdá Katarína

    2015-12-01

    Full Text Available This paper deals with the optimal design of thickness of a plate rested on Winkler’s foundation. First order method was used for the optimization, while maintaining different restrictive conditions. The aim is to obtain a minimum volume of the foundation plate. At the end some probabilistic and safety analysis of the deflection of the foundation using LHS Monte Carlo method are presented.

  7. Data set for transcriptome analysis of the Chinese giant salamander (Andrias davidianus

    Directory of Open Access Journals (Sweden)

    Xuemei Jiang

    2016-03-01

    Full Text Available The Chinese giant salamander (Andrias davidianus occupies a seat at the phylogenetic and species evolution process, which makes it an invaluable model for genetics; however, the genetic information and gene sequences about the Chinese giant salamander in public databases are scanty. Hence, we aimed to perform transcriptome analysis with the help of high-throughput sequencing. In this data, 61,317,940 raw reads were acquired from Chinese giant salamander mRNA using Illumina paired-end sequencing platform. After de novo assembly, a total of 72,072 unigenes were gained, in which 33,834 (46.95% and 29,479 (40.91% transcripts exhibited homology to sequences in the Nr database and Swiss-Prot database, (E-value <10−5, respectively. In the obtained unigenes, 18,019 (25% transcripts were assigned with at least one Gene Ontology term, of which 1218 (6.8% transcripts were assigned to immune system processes. In addition, a total of 17,572 assembled sequences were assigned into 241 predicted KEGG metabolic pathways. Among these, 2552 (14.5% transcripts were assigned to the immune system relevant pathway and 5 transcripts were identified as potential antimicrobial peptides (AMPs. Keywords: Andrias davidianus, Transcriptome

  8. Miniaturized inertial impactor for personal airborne particulate monitoring: Prototyping

    Science.gov (United States)

    Pasini, Silvia; Bianchi, Elena; Dubini, Gabriele; Cortelezzi, Luca

    2017-11-01

    Computational fluid dynamic (CFD) simulations allowed us to conceive and design a miniaturized inertial impactor able to collect fine airborne particulate matter (PM10, PM2.5 and PM1). We created, by 3D printing, a prototype of the impactor. We first performed a set of experiments by applying a suction pump to the outlets and sampling the airborne particulate of our laboratory. The analysis of the slide showed a collection of a large number of particles, spanning a wide range of sizes, organized in a narrow band located below the exit of the nozzle. In order to show that our miniaturized inertial impactor can be truly used as a personal air-quality monitor, we performed a second set of experiments where the suction needed to produce the airflow through the impactor is generated by a human being inhaling through the outlets of the prototype. To guarantee a number of particles sufficient to perform a quantitative characterization, we collected particles performing ten consecutive deep inhalations. Finally, the potentiality for realistic applications of our miniaturized inertial impactor used in combination with a miniaturized single-particle detector will be discussed. CARIPLO Fundation - project MINUTE (Grant No. 2011-2118).

  9. Finite element analysis of displacement actuator based on giant magnetostrictive thin film

    Directory of Open Access Journals (Sweden)

    Shaopeng Yu

    2018-05-01

    Full Text Available With the rapid development of science and technology, mechanical and electrical equipment become more and more miniature. In order to achieve precise control in less than 1cm3, the giant magnetostrictive thin film has become a research hotspot. The micro displacement actuator with planar and arc film is designed by the dynamic coupling model based on J-A model and magneto-mechanical effect method which is proposed in this paper. The different structure and thickness of films are analyzed by COMSOL Multiphysics software when the current flows through driving coil. After comparing the simulation results with the test ones, it can be seen that the coupling model is accurate and the structure is reliable. At the same time, MATLAB is used to fit the current density-displacement curve and higher order equation is obtained, and then the feasibility of design can be verified. The actuator with arc structure had advantages of small volume, fast response, high precision, easy integration, etc., which has a broad application prospect in the field of vibration control, micro positioning, robot and so on.

  10. Finite element analysis of displacement actuator based on giant magnetostrictive thin film

    Science.gov (United States)

    Yu, Shaopeng; Wang, Bowen; Zhang, Changgeng; Cui, Baozhi

    2018-05-01

    With the rapid development of science and technology, mechanical and electrical equipment become more and more miniature. In order to achieve precise control in less than 1cm3, the giant magnetostrictive thin film has become a research hotspot. The micro displacement actuator with planar and arc film is designed by the dynamic coupling model based on J-A model and magneto-mechanical effect method which is proposed in this paper. The different structure and thickness of films are analyzed by COMSOL Multiphysics software when the current flows through driving coil. After comparing the simulation results with the test ones, it can be seen that the coupling model is accurate and the structure is reliable. At the same time, MATLAB is used to fit the current density-displacement curve and higher order equation is obtained, and then the feasibility of design can be verified. The actuator with arc structure had advantages of small volume, fast response, high precision, easy integration, etc., which has a broad application prospect in the field of vibration control, micro positioning, robot and so on.

  11. Giant multipole resonances: an experimental review

    International Nuclear Information System (INIS)

    Bertrand, F.E.

    1979-01-01

    During the past several years experimental evidence has been published for the existance of nondipole giant resonances. These giant multipole resonances, the so-called new giant resonances were first observed through inelastic hadron and electron scattering and such measurements have continued to provide most of the information in this field. A summary is provided of the experimental evidence for these new resonances. The discussion deals only with results from inelastic scattering and only with the electric multipoles. Emphasis is placed on the recent observations of the giant monopole resonance. Results from recent heavy-ion and pion inelastic scattering are discussed. 38 references

  12. Giant dipole resonance in hot nuclei

    International Nuclear Information System (INIS)

    Mau, N.V.

    1993-01-01

    Giant resonances built on an excited state of the nucleus at a finite temperature T are studied. The following questions are investigated: how long such collective effects occur in a nucleus when T increases. How the properties of the giant resonances vary when the temperature increases. How the study of giant resonances in hot nuclei can give information on the structure of the nucleus in a highly excited state. The special case of the giant dipole resonance is studied. Some of the experimental results are reviewed and in their theoretical interpretation is discussed. (K.A.). 56 refs., 20 figs., 4 tabs

  13. Granulomatous interstitial pneumonia in a miniature swine associated with repeated intravenous injections of Tc-99m human serum albumin: concise communication

    International Nuclear Information System (INIS)

    Whinnery, J.E.; Young, J.T.

    1980-01-01

    Albumin lung-scanning agents have a proven high degree of safety, with the only contraindication to their use being allergic hypersensitivity. We have used these agents to investigate the physiologic effects of high G/sub z/ acceleratory forces on pulmonary perfusion using the miniature swine. Multiple doses of human macroaggregated albumin and human-albumin microspheres were given to a miniature swine at various levels of centrifugal acceleration over a 6-wk period. The dosages given were the same per kilogram as those used for routine clinical human studies. The animal subsequently died from a severe granulomatous interstitial pneumonia. The granulomatous lesions suggest that the pathogenesis may have involved a cell-mediated delayed hypersensitivity. This interstitial pneumonia may represent the end point in a chronic hypersensitivity response to the human-albumin lung-scanning agents

  14. Electrified BPS giants: BPS configurations on giant gravitons with static electric field

    International Nuclear Information System (INIS)

    Ali-Akbari, Mohammad; Sheikh-Jabbari, Mohammad Mahdi

    2007-01-01

    We consider D3-brane action in the maximally supersymmetric type IIB plane-wave background. Upon fixing the light-cone gauge, we obtain the light-cone Hamiltonian which is manifestly supersymmetric. The 1/2 BPS solutions of this theory (solutions which preserve 16 supercharges) are either of the form of spherical three branes, the giant gravitons, or zero size point like branes. We then construct specific classes of 1/4 BPS solutions of this theory in which static electric field on the brane is turned on. These solutions are deformations about either of the two 1/2 BPS solutions. In particular, we study in some detail 1/4 BPS configurations with electric dipole on the three sphere giant, i.e. BIons on the giant gravitons, which we hence call BIGGons. We also study BPS configurations corresponding to turning on a background uniform constant electric field. As a result of this background electric field the three sphere giant is deformed to squashed sphere, while the zero size point like branes turn into circular or straight fundamental strings in the plane-wave background, with their tension equal to the background electric field

  15. 46 CFR 52.25-5 - Miniature boilers (modifies PMB-1 through PMB-21).

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 2 2010-10-01 2010-10-01 false Miniature boilers (modifies PMB-1 through PMB-21). 52.25... ENGINEERING POWER BOILERS Other Boiler Types § 52.25-5 Miniature boilers (modifies PMB-1 through PMB-21). Miniature boilers must meet the applicable provisions in this part for the boiler type involved and the...

  16. Development of fatigue life evaluation technique using miniature specimen

    International Nuclear Information System (INIS)

    Nogami, Shuhei; Nishimura, Arata; Fujiwara, Masaharu; Hisaka, Tomoaki

    2012-01-01

    To develop the fatigue life evaluation technique using miniature specimen, the investigation of the effect of specimen size and specimen shape on the fatigue life and the development of the fatigue testing machine, especially the extensometer, were carried out. The effect of specimen size on the fatigue life was almost negligible for the round-bar specimens. The shorter fatigue life at relatively low strain range conditions for the hourglass specimen that the standard specimen were observed. Therefore the miniature round-bar specimen was considered to be adequate for the fatigue life evaluation using small specimen. Several types of the extensometer system using a strain gauge and a laser has been developed for realizing the fatigue test of the miniature round-bar specimen at high temperature in vacuum. (author)

  17. Giant cells around bone biomaterials: Osteoclasts or multi-nucleated giant cells?

    Science.gov (United States)

    Miron, Richard J; Zohdi, Hamoon; Fujioka-Kobayashi, Masako; Bosshardt, Dieter D

    2016-12-01

    Recently accumulating evidence has put into question the role of large multinucleated giant cells (MNGCs) around bone biomaterials. While cells derived from the monocyte/macrophage lineage are one of the first cell types in contact with implanted biomaterials, it was originally thought that specifically in bone tissues, all giant cells were bone-resorbing osteoclasts whereas foreign body giant cells (FBGCs) were found associated with a connective tissue foreign body reaction resulting in fibrous encapsulation and/or material rejection. Despite the great majority of bone grafting materials routinely found with large osteoclasts, a special subclass of bone biomaterials has more recently been found surrounded by large giant cells virtually incapable of resorbing bone grafts even years after their implantation. While original hypotheses believed that a 'foreign body reaction' may be taking place, histological data retrieved from human samples years after their implantation have put these original hypotheses into question by demonstrating better and more stable long-term bone volume around certain bone grafts. Exactly how or why this 'special' subclass of giant cells is capable of maintaining long-term bone volume, or methods to scientifically distinguish them from osteoclasts remains extremely poorly studied. The aim of this review article was to gather the current available literature on giant cell markers and differences in expression patterns between osteoclasts and MNGCs utilizing 19 specific markers including an array of CD-cell surface markers. Furthermore, the concept of now distinguishing between pro-inflammatory M1-MNGCs (previously referred to as FBGCs) as well as wound-healing M2-MNGCs is introduced and discussed. This review article presents 19 specific cell-surface markers to distinguish between osteoclasts and MNGCs including an array of CD-cell surface markers. Furthermore, the concept of now distinguishing between pro-inflammatory M1-MNGCs (often

  18. The effect of plate thickness, surface tension and fluid flow on detachment of drops from a plate

    NARCIS (Netherlands)

    Lexmond, A.S.; Geld, van der C.W.M.; Celata, G.P.

    2004-01-01

    The pinch-off of drops from the downstream end of plates is an important re-entrainment mechanism of condensate in compact condensers. The present experimental study complements a previous one [1], in which ethanol and water drops were created for various mass densities and gas velocities at the

  19. Glomerular Lesions in Proteinuric Miniature Schnauzer Dogs.

    Science.gov (United States)

    Furrow, E; Lees, G E; Brown, C A; Cianciolo, R E

    2017-05-01

    Miniature Schnauzer dogs are predisposed to idiopathic hypertriglyerceridemia, which increases risk for diseases such as pancreatitis and gallbladder mucocele. Recently, elevated triglyceride concentrations have been associated with proteinuria in this breed, although it is difficult to determine which abnormality is primary. Retrospective review of renal tissue from 27 proteinuric Miniature Schnauzers revealed that 20 dogs had ultrastructural evidence of osmophilic globules consistent with lipid in glomerular tufts. Seven of these dogs had lipid thromboemboli in glomerular capillary loops that distorted their shape and compressed circulating erythrocytes. Triglyceride concentrations were reported in 6 of these 7 dogs, and all were hypertriglyceridemic. In addition, glomerular lipidosis (defined as accumulation of foam cells within peripheral capillary loops) was identified in a single dog. The remaining 12 dogs had smaller amounts of lipid that could only be identified ultrastructurally. Neither signalment data nor clinicopathologic parameters (serum albumin, serum creatinine, urine protein-to-creatinine ratio, and blood pressure) differed among the various types of lipid lesions. During the time course of this study, all dogs diagnosed with glomerular lipid thromboemboli were Miniature Schnauzers, underscoring the importance of recognizing these clear spaces within capillary loops as lipid.

  20. A device for thermally insulating a concrete wall covered with a thermal plate

    International Nuclear Information System (INIS)

    Cornille, Yvon; Felten, Paul.

    1973-01-01

    The device is characterized in that it comprises a stack of bricks of parallelepipedic shape of cellular silica, bound to one another and to a metal plate by means of a silica-mortar layer and of anchoring keys welded to the metal plate, at one end thereof, and embedded in at least two juxtaposed bricks, at the other end thereof. This can be used for unsulating the cavity located under the core of a high temperature reactor [fr

  1. Miniature tensile test specimens for fusion reactor irradiation studies

    International Nuclear Information System (INIS)

    Klueh, R.L.

    1985-01-01

    Three miniature sheet-type tensile specimens and a miniature rod-type specimen are being used to determine irradiated tensile properties for alloy development for fusion reactors. The tensile properties of type 316 stainless steel were determined with these different specimens, and the results were compared. Reasonably good agreement was observed. However, there were differences that led to recommendations on which specimens are preferred. 4 references, 9 figures, 6 tables

  2. Miniature bread baking as a timesaving research approach and mathematical modeling of browning kinetics

    NARCIS (Netherlands)

    Zhang, Lu; Putranto, Aditya; Zhou, Weibiao; Boom, Remko M.; Schutyser, Maarten A.I.; Chen, Xiao Dong

    2016-01-01

    Miniature bread baking is presented as an economical and timesaving laboratory approach to study the baking process in the present work. Results indicate that the miniature bread baking is essentially analogical to the baking process of regular-sized bread: quality-related properties of miniature

  3. Miniature Raman spectrometer development

    Science.gov (United States)

    Bonvallet, Joseph; Auz, Bryan; Rodriguez, John; Olmstead, Ty

    2018-02-01

    The development of techniques to rapidly identify samples ranging from, molecule and particle imaging to detection of high explosive materials, has surged in recent years. Due to this growing want, Raman spectroscopy gives a molecular fingerprint, with no sample preparation, and can be done remotely. These systems can be small, compact, lightweight, and with a user interface that allows for easy use and sample identification. Ocean Optics Inc. has developed several systems that would meet all these end user requirements. This talk will describe the development of different Ocean Optics Inc miniature Raman spectrometers. The spectrometer on a phone (SOAP) system was designed using commercial off the shelf (COTS) components, in a rapid product development cycle. The footprint of the system measures 40x40x14 mm (LxWxH) and was coupled directly to the cell phone detector camera optics. However, it gets roughly only 40 cm-1 resolution. The Accuman system is the largest (290x220X100 mm) of the three, but uses our QEPro spectrometer and get 7-11 cm-1 resolution. Finally, the HRS-30 measuring 165x85x40 mm is a combination of the other two systems. This system uses a modified EMBED spectrometer and gets 7-12 cm-1 resolution. Each of these units uses a peak matching algorithm that then correlates the results to the pre-loaded and customizable spectral libraries.

  4. Giant Planets: Good Neighbors for Habitable Worlds?

    Science.gov (United States)

    Georgakarakos, Nikolaos; Eggl, Siegfried; Dobbs-Dixon, Ian

    2018-04-01

    The presence of giant planets influences potentially habitable worlds in numerous ways. Massive celestial neighbors can facilitate the formation of planetary cores and modify the influx of asteroids and comets toward Earth analogs later on. Furthermore, giant planets can indirectly change the climate of terrestrial worlds by gravitationally altering their orbits. Investigating 147 well-characterized exoplanetary systems known to date that host a main-sequence star and a giant planet, we show that the presence of “giant neighbors” can reduce a terrestrial planet’s chances to remain habitable, even if both planets have stable orbits. In a small fraction of systems, however, giant planets slightly increase the extent of habitable zones provided that the terrestrial world has a high climate inertia. In providing constraints on where giant planets cease to affect the habitable zone size in a detrimental fashion, we identify prime targets in the search for habitable worlds.

  5. Miniaturization design and implementation of magnetic field coupled RFID antenna

    Science.gov (United States)

    Hu, Tiling

    2013-03-01

    The development of internet of things has brought new opportunities and challenges to the application of RFID tags. Moreover, the Miniaturization application trend of tags at present has become the mainstream of development. In this paper, the double-layer design is to reduce the size of HF antenna, and the magnetic null point of magnetic reconnection region between the RLC resonant circuit and the reader provides sufficient energy to the miniaturization of antenna. The calculated and experimental results show that the miniaturization of HF antennas can meet the reading and writing requirement of the international standard ISO/IEC14443 standard. The results of this paper may make a positive contribution to the applications of RFID technology.

  6. Nonlinear, anisotropic, and giant photoconductivity in intrinsic and doped graphene

    Science.gov (United States)

    Singh, Ashutosh; Ghosh, Saikat; Agarwal, Amit

    2018-01-01

    We present a framework to calculate the anisotropic and nonlinear photoconductivity for two band systems with application to graphene. In contrast to the usual perturbative (second order in the optical field strength) techniques, we calculate photoconductivity to all orders in the optical field strength. In particular, for graphene, we find the photoresponse to be giant (at large optical field strengths) and anisotropic. The anisotropic photoresponse in graphene is correlated with polarization of the incident field, with the response being similar to that of a half-wave plate. We predict that the anisotropy in the simultaneous measurement of longitudinal (σx x) and transverse (σy x) photoconductivity, with four probes, offers a unique experimental signature of the photovoltaic response, distinguishing it from the thermal-Seebeck and bolometric effects in photoresponse.

  7. Miniaturized test system for soil respiration induced by volatile pollutants

    International Nuclear Information System (INIS)

    Kaufmann, Karin; Chapman, Stephen J.; Campbell, Colin D.; Harms, Hauke; Hoehener, Patrick

    2006-01-01

    A miniaturized method based on 96-well microtitre plates was developed and used to study respiration in pristine and contaminated soils following addition of volatile substrates. Small soil samples were exposed to fuel components, which were volatilized from spatially separate reservoirs of 2,2,4,4,6,8,8-heptamethylnonane (HMN) as an organic carrier. Respiration was determined as CO 2 production by means of a pH-indicator and bicarbonate-containing agar, or as 14 CO 2 evolution from 14 C-labelled substrates. Substrate concentrations inducing maximum microbial activity or inhibition were determined and CO 2 production profiles examined by multivariate analysis. When high concentrations of fuel components were applied, distinction of hydrocarbon exposed soils from unexposed soil was achieved within 6 h of incubation. With low concentrations, adequate distinction was achieved after 24 h, probably as a result of community adaptation. Nutrient limitation was identified with the 14 C method for toluene, and the optimal N and P amendment determined. Further potential applications of this rapid and inexpensive method are outlined. - A new method to study soil respiration is used when volatile organic contaminants are added

  8. Evaluation of the cationic trypsinogen gene for potential mutations in miniature schnauzers with pancreatitis.

    Science.gov (United States)

    Bishop, Micah A; Steiner, Jörg M; Moore, Lisa E; Williams, David A

    2004-10-01

    The purpose of this study was to evaluate the cationic trypsinogen gene in miniature schnauzers for possible mutations. Genetic mutations have been linked with hereditary pancreatitis in humans. Four miniature schnauzers were selected on the basis of a clinical history of pancreatitis. One healthy miniature schnauzer and 1 healthy mixed breed canine were enrolled as controls. DNA was extracted from these canines using a commercial kit. Primers were designed to amplify the entire canine cationic trypsinogen cDNA sequence. A polymerase chain reaction (PCR) was performed and products were purified and sequenced. All sequences were then compared. The healthy control canine, a healthy miniature schnauzer, and the 4 miniature schnauzers with pancreatitis showed identical sequences of the cationic trypsinogen gene to the published sequence. We conclude that, in contrast to humans with hereditary pancreatitis, mutations of the cationic trypsinogen gene do not play a major role in the genesis of pancreatitis in the miniature schnauzer.

  9. Should the Endangered Status of the Giant Panda Really Be Reduced? The Case of Giant Panda Conservation in Sichuan, China.

    Science.gov (United States)

    Ma, Ben; Lei, Shuo; Qing, Qin; Wen, Yali

    2018-05-03

    The International Union for Conservation of Nature (IUCN) reduced the threat status of the giant panda from “endangered” to “vulnerable” in September 2016. In this study, we analyzed current practices for giant panda conservation at regional and local environmental scales, based on recent reports of giant panda protection efforts in Sichuan Province, China, combined with the survey results from 927 households within and adjacent to the giant panda reserves in this area. The results showed that household attitudes were very positive regarding giant panda protection efforts. Over the last 10 years, farmers’ dependence on the natural resources provided by giant panda reserves significantly decreased. However, socio-economic development increased resource consumption, and led to climate change, habitat fragmentation, environmental pollution, and other issues that placed increased pressure on giant panda populations. This difference between local and regional scales must be considered when evaluating the IUCN status of giant pandas. While the status of this species has improved in the short-term due to positive local attitudes, large-scale socio-economic development pressure could have long-term negative impacts. Consequently, the IUCN assessment leading to the classification of giant panda as “vulnerable” instead of “endangered”, should not affect its conservation intensity and effort, as such actions could negatively impact population recovery efforts, leading to the extinction of this charismatic species.

  10. Should the Endangered Status of the Giant Panda Really Be Reduced? The Case of Giant Panda Conservation in Sichuan, China

    Directory of Open Access Journals (Sweden)

    Ben Ma

    2018-05-01

    Full Text Available The International Union for Conservation of Nature (IUCN reduced the threat status of the giant panda from “endangered” to “vulnerable” in September 2016. In this study, we analyzed current practices for giant panda conservation at regional and local environmental scales, based on recent reports of giant panda protection efforts in Sichuan Province, China, combined with the survey results from 927 households within and adjacent to the giant panda reserves in this area. The results showed that household attitudes were very positive regarding giant panda protection efforts. Over the last 10 years, farmers’ dependence on the natural resources provided by giant panda reserves significantly decreased. However, socio-economic development increased resource consumption, and led to climate change, habitat fragmentation, environmental pollution, and other issues that placed increased pressure on giant panda populations. This difference between local and regional scales must be considered when evaluating the IUCN status of giant pandas. While the status of this species has improved in the short-term due to positive local attitudes, large-scale socio-economic development pressure could have long-term negative impacts. Consequently, the IUCN assessment leading to the classification of giant panda as “vulnerable” instead of “endangered”, should not affect its conservation intensity and effort, as such actions could negatively impact population recovery efforts, leading to the extinction of this charismatic species.

  11. A search for lithium-rich giant stars

    International Nuclear Information System (INIS)

    Brown, J.A.; Sneden, C.; Lambert, D.L.; Dutchover, E. Jr.

    1989-01-01

    Lithium abundances or upper limits have been determined for 644 bright G-K giant stars selected from the DDO photometric catalog. Two of these giants possess surface lithium abundances approaching the cosmic value of the interstellar medium and young main-sequence stars, and eight more giants have Li contents far in excess of standard predictions. At least some of these Li-rich giants are shown to be evolved to the stage of having convectively mixed envelopes, either from the direct evidence of low surface carbon isotope ratios, or from the indirect evidence of their H-R diagram positions. Suggestions are given for the unique conditions that might have allowed these stars to produce or accrete new lithium for their surface layers, or simply to preserve from destruction their initial lithium contents. The lithium abundance of the remaining stars demonstrates that giants only very rarely meet the expectations of standard first dredge-up theories; the average extra Li destruction required is about 1.5 dex. The evolutionary states of these giants and their average masses are discussed briefly, and the Li distribution of the giants is compared to predictions of Galactic chemical evolution. 110 refs

  12. Macroscopic description of isoscalar giant multipole resonances

    International Nuclear Information System (INIS)

    Nix, J.R.; Sierk, A.J.

    1980-01-01

    On the basis of a simple macroscopic model, we calculate the isoscalar giant-resonance energy as a function of mass number and multipole degree. The restoring force is determined from the distortion of the Fermi surface, and the inertia is determined for the incompressible, irrotational flow of nucleons with unit effective mass. With no adjustable parameters, the resulting closed expression reproduces correctly the available experimental data, namely the magnitude and dependence upon mass number of the giant quadrupole energy and the magnitude of the giant octupole energy for 208 Pb. We also calculate the isoscalar giant-resonance width as a function of mass number and multipole degree for various macroscopic damping mechanisms, including two-body viscosity, one-body dissipation, and modified one-body dissipation. None of these damping mechanisms reproduces correctly all features of the available experimental data, namely the magnitude and dependence upon mass number of the giant quadrupole width and the magnitude of the giant octupole width for 208 Pb

  13. Giant panda BAC library construction and assembly of a 650-kb contig spanning major histocompatibility complex class II region

    Directory of Open Access Journals (Sweden)

    Pan Hui-Juan

    2007-09-01

    Full Text Available Abstract Background Giant panda is rare and endangered species endemic to China. The low rates of reproductive success and infectious disease resistance have severely hampered the development of captive and wild populations of the giant panda. The major histocompatibility complex (MHC plays important roles in immune response and reproductive system such as mate choice and mother-fetus bio-compatibility. It is thus essential to understand genetic details of the giant panda MHC. Construction of a bacterial artificial chromosome (BAC library will provide a new tool for panda genome physical mapping and thus facilitate understanding of panda MHC genes. Results A giant panda BAC library consisting of 205,800 clones has been constructed. The average insert size was calculated to be 97 kb based on the examination of 174 randomly selected clones, indicating that the giant panda library contained 6.8-fold genome equivalents. Screening of the library with 16 giant panda PCR primer pairs revealed 6.4 positive clones per locus, in good agreement with an expected 6.8-fold genomic coverage of the library. Based on this BAC library, we constructed a contig map of the giant panda MHC class II region from BTNL2 to DAXX spanning about 650 kb by a three-step method: (1 PCR-based screening of the BAC library with primers from homologous MHC class II gene loci, end sequences and BAC clone shotgun sequences, (2 DNA sequencing validation of positive clones, and (3 restriction digest fingerprinting verification of inter-clone overlapping. Conclusion The identifications of genes and genomic regions of interest are greatly favored by the availability of this giant panda BAC library. The giant panda BAC library thus provides a useful platform for physical mapping, genome sequencing or complex analysis of targeted genomic regions. The 650 kb sequence-ready BAC contig map of the giant panda MHC class II region from BTNL2 to DAXX, verified by the three-step method, offers a

  14. Tests of the Giant Impact Hypothesis

    Science.gov (United States)

    Jones, J. H.

    1998-01-01

    The giant impact hypothesis has gained popularity as a means of explaining a volatile-depleted Moon that still has a chemical affinity to the Earth. As Taylor's Axiom decrees, the best models of lunar origin are testable, but this is difficult with the giant impact model. The energy associated with the impact would be sufficient to totally melt and partially vaporize the Earth. And this means that there should he no geological vestige of Barber times. Accordingly, it is important to devise tests that may be used to evaluate the giant impact hypothesis. Three such tests are discussed here. None of these is supportive of the giant impact model, but neither do they disprove it.

  15. Hadron excitation of giant resonances

    International Nuclear Information System (INIS)

    Morsch, H.-P.

    1985-01-01

    A review is given on giant resonance studies in heavy nuclei using scattering of different hadronic probes. Concerning isoscalar giant resonances compression modes are discussed with the possibility to obtain more detailed structure information. From detailed studies of α scattering the distribution of isoscalar strengths of multipolarity up to L=6 was obtained. Some recent aspects of heavy ion excitation of collective modes are mentioned. The possibility to study isovector giant resonances in hadron charge exchange reactions is discussed. Finally, a comparison is made between α and 200 MeV proton scattering from which isoscalar and spin-isospin continuum response are extracted. (orig.)

  16. Irradiation of novel MTR fuel plates in BR2

    International Nuclear Information System (INIS)

    Verboomen, B.; Aoust, Th.; Beeckmans De Westmeerbeeck, A.; De Raedt, Ch.

    2000-01-01

    Since the end of 1999, novel MTR fuel plates with very high-density meat are being irradiated in BR2. The purpose of the irradiation is to investigate the behaviour of these fuel plates under very severe reactor operation conditions. The novel fuel plates are inserted in two standard six-tube BR2 fuel elements in the locations normally occupied by the standard outer fuel plates. The irradiation in BR2 was prepared by carrying out detailed neutron Monte Carlo calculations of the whole BR2 core containing the two experimental fuel elements for various positions in the reactor and for various azimuthal orientations of the fuel elements. Comparing the thus determined fission density levels and azimuthal profiles in the new MTR fuel plates irradiated in the various channels allowed the experimenters to choose the most appropriate BR2 channel and the most appropriate fuel element orientation. (author)

  17. DETECTION OF ORIENTED NUMBER PLATE IN VEHICLE USING AUTOCORRECTION FEATURE FROM GRAY LEVEL CO-OCCURENCE MATRIX

    OpenAIRE

    Veena M.N; Shruthi S.J; Vasudev.T

    2016-01-01

    The efficiency of an automatic number plate recognition system depends directly on the proper effective preprocessing of the number plate. The OCRs available for recognition are capable of reading the number plates which are in proper orientation of 00. In many situations the vehicle number plates captured may be in any different orientation like 900, 1800 and 2700. These orientations in number plates are due to declamping of number plate at one end or toppling of vehicle. Such differently...

  18. Laser direct marking applied to rasterizing miniature Data Matrix Code on aluminum alloy

    Science.gov (United States)

    Li, Xia-Shuang; He, Wei-Ping; Lei, Lei; Wang, Jian; Guo, Gai-Fang; Zhang, Teng-Yun; Yue, Ting

    2016-03-01

    Precise miniaturization of 2D Data Matrix (DM) Codes on Aluminum alloy formed by raster mode laser direct part marking is demonstrated. The characteristic edge over-burn effects, which render vector mode laser direct part marking inadequate for producing precise and readable miniature codes, are minimized with raster mode laser marking. To obtain the control mechanism for the contrast and print growth of miniature DM code by raster laser marking process, the temperature field model of long pulse laser interaction with material is established. From the experimental results, laser average power and Q frequency have an important effect on the contrast and print growth of miniature DM code, and the threshold of laser average power and Q frequency for an identifiable miniature DM code are respectively 3.6 W and 110 kHz, which matches the model well within normal operating conditions. In addition, the empirical model of correlation occurring between laser marking parameters and module size is also obtained, and the optimal processing parameter values for an identifiable miniature DM code of different but certain data size are given. It is also found that an increase of the repeat scanning number effectively improves the surface finish of bore, the appearance consistency of modules, which has benefit to reading. The reading quality of miniature DM code is greatly improved using ultrasonic cleaning in water by avoiding the interference of color speckles surrounding modules.

  19. Use of urinary 13,14, dihydro-15-keto-prostaglandin F2α (PGFM) concentrations to diagnose pregnancy and predict parturition in the giant panda (Ailuropoda melanolecua).

    Science.gov (United States)

    Roberts, Beth M; Brown, Janine L; Kersey, David C; Snyder, Rebecca J; Durrant, Barbara S; Kouba, Andrew J

    2018-01-01

    Pregnancy determination is difficult in the giant panda (Ailuropoda melanolecua), representing a challenge for ex situ conservation efforts. Research in other species experiencing pseudopregnancy indicates that urinary/fecal concentrations of 13,14, dihydro-15-keto-prostaglandin F2α (PGFM) can accurately determine pregnancy status. Our objective was to determine if urinary PGFM concentrations are associated with pregnancy status in the giant panda. Urinary PGFM concentrations were measured in female giant pandas (n = 4) throughout gestation (n = 6) and pseudopregnancy (n = 4) using a commercial enzyme immunoassay. Regardless of pregnancy status, PGFM excretion followed a predictable pattern: 1) baseline concentrations for 11-19 weeks following ovulation; 2) a modest, initial peak 14-36 days after the start of the secondary urinary progestagen rise; 3) a subsequent period of relatively low concentrations; and 4) a large, terminal peak at the end of the luteal phase. Pregnant profiles were distinguished by an earlier initial peak (P = 0.024), higher inter-peak concentrations (P panda. Furthermore, this is the only species known to exhibit a significant PGFM increase during pseudopregnancy, suggesting a unique physiological mechanism for regulating the end of the luteal phase in the giant panda.

  20. Ultrasonic inspection of tube to tube plate welds

    International Nuclear Information System (INIS)

    Telford, D.W.; Peat, T.S.

    1985-01-01

    To monitor the deterioration of a weld between a tube and tube plate which has been repaired by a repair sleeve inside the tube and brazed at one end to the tube, ultrasound from a crystal at the end of a rod is launched, in the form of Lamb-type waves, into the tube through the braze and allowed to travel along the tube to the weld and be reflected back along the tube. The technique may also be used for the type of heat exchanger in which, during construction, the tubes are welded to the tube plate via external sleeves in which case the ultrasound is used in a similar manner to inspect the sleeve/tube plate weld. an electromagnetic transducer may be used to generate the ultrasound. The ultrasonic head comprising the crystal and an acoustic baffle is mounted on a Perspex (RTM) rod which may be rotated by a stepping motor. Echo signals from the region of deterioration may be isolated by use of a time gate in the receiver. The device primarily detects circumferentially orientated cracks, and may be used in heat exchangers in nuclear power plants. (author)

  1. YOUNG SOLAR SYSTEM's FIFTH GIANT PLANET?

    International Nuclear Information System (INIS)

    Nesvorný, David

    2011-01-01

    Studies of solar system formation suggest that the solar system's giant planets formed and migrated in the protoplanetary disk to reach the resonant orbits with all planets inside ∼15 AU from the Sun. After the gas disk's dispersal, Uranus and Neptune were likely scattered by the gas giants, and approached their current orbits while dispersing the transplanetary disk of planetesimals, whose remains survived to this time in the region known as the Kuiper Belt. Here we performed N-body integrations of the scattering phase between giant planets in an attempt to determine which initial states are plausible. We found that the dynamical simulations starting with a resonant system of four giant planets have a low success rate in matching the present orbits of giant planets and various other constraints (e.g., survival of the terrestrial planets). The dynamical evolution is typically too violent, if Jupiter and Saturn start in the 3:2 resonance, and leads to final systems with fewer than four planets. Several initial states stand out in that they show a relatively large likelihood of success in matching the constraints. Some of the statistically best results were obtained when assuming that the solar system initially had five giant planets and one ice giant, with the mass comparable to that of Uranus and Neptune, and which was ejected to interstellar space by Jupiter. This possibility appears to be conceivable in view of the recent discovery of a large number of free-floating planets in interstellar space, which indicates that planet ejection should be common.

  2. Young Solar System's Fifth Giant Planet?

    Science.gov (United States)

    Nesvorný, David

    2011-12-01

    Studies of solar system formation suggest that the solar system's giant planets formed and migrated in the protoplanetary disk to reach the resonant orbits with all planets inside ~15 AU from the Sun. After the gas disk's dispersal, Uranus and Neptune were likely scattered by the gas giants, and approached their current orbits while dispersing the transplanetary disk of planetesimals, whose remains survived to this time in the region known as the Kuiper Belt. Here we performed N-body integrations of the scattering phase between giant planets in an attempt to determine which initial states are plausible. We found that the dynamical simulations starting with a resonant system of four giant planets have a low success rate in matching the present orbits of giant planets and various other constraints (e.g., survival of the terrestrial planets). The dynamical evolution is typically too violent, if Jupiter and Saturn start in the 3:2 resonance, and leads to final systems with fewer than four planets. Several initial states stand out in that they show a relatively large likelihood of success in matching the constraints. Some of the statistically best results were obtained when assuming that the solar system initially had five giant planets and one ice giant, with the mass comparable to that of Uranus and Neptune, and which was ejected to interstellar space by Jupiter. This possibility appears to be conceivable in view of the recent discovery of a large number of free-floating planets in interstellar space, which indicates that planet ejection should be common.

  3. Determination of absorbed dose to water from a miniature kilovoltage x-ray source using a parallel-plate ionization chamber

    Science.gov (United States)

    Watson, Peter G. F.; Popovic, Marija; Seuntjens, Jan

    2018-01-01

    Electronic brachytherapy sources are widely accepted as alternatives to radionuclide-based systems. Yet, formal dosimetry standards for these devices to independently complement the dose protocol provided by the manufacturer are lacking. This article presents a formalism for calculating and independently verifying the absorbed dose to water from a kV x-ray source (The INTRABEAM System) measured in a water phantom with an ionization chamber calibrated in terms of air-kerma. This formalism uses a Monte Carlo (MC) calculated chamber conversion factor, CQ , to convert air-kerma in a reference beam to absorbed dose to water in the measurement beam. In this work CQ was determined for a PTW 34013 parallel-plate ionization chamber. Our results show that CQ was sensitive to the chamber plate separation tolerance, with differences of up to 15%. CQ was also found to have a depth dependence which varied with chamber plate separation (0 to 10% variation for the smallest and largest cavity height, over 3 to 30 mm depth). However for all chamber dimensions investigated, CQ was found to be significantly larger than the manufacturer reported value, suggesting that the manufacturer recommended method of dose calculation could be underestimating the dose to water.

  4. Giant multipole resonances: perspectives after ten years

    International Nuclear Information System (INIS)

    Bertrand, F.E.

    1980-01-01

    Nearly ten years ago evidence was published for the first of the so-called giant multipole resonances, the giant quadrupole resonance. During the ensuing years research in this field has spread to many nuclear physics laboratories throughout the world. The present status of electric giant multipole resonances is reviewed. 24 figures, 1 table

  5. Growth plate closure: Apex view on bone scan

    International Nuclear Information System (INIS)

    Giles, P.H.; Trochei, M.; Yeates, K.

    1984-01-01

    Angular deformities of the extremities in children following premature closure of the growth plate are well known. The deformities depend on the position of an osseus bridge which forms between the epiphysis and metaphysis. Several surgical procedures including resection of the osseus bridge have been described, however, delineation of the site of fusion is difficult to define. The commonest site of growth plate arrest is the distal femoral or proximal tibial growth plate. A new technique using the bone scan has been developed which accurately defines the area and position of these osseus bridges. Two hours after injection of technetium 99m methylene diphosphonate apex views of the affected distal femoral growth plate were performed. The knee was flexed into its smallest angle. Using a pinhole collimator the gamma camera was angled to face the affected growth plate end on. The image was collected onto computer and analysed by: (I) regions of interest over segments of the growth plate to calculate the relative area of total growth plate affected: (II) generating histograms: (III) thresholding or performing isocontours to accentuate abnormal areas. The growth plate is normally uniformly increased when compared to the normal shaft of the bone. Fusion across the plate appears as an area of diminished uptake. The apex view gives a unique functional map of the growth plate such that abnormal areas are displayed, and the site, size and position of osseus fusion obtained. The technique has the potential for determining the metabolic activity of the growth plate before and after surgery. Serial studies will allow assessment of regneration of the plate and reformation of new osseus bridges

  6. Central Giant Cell Granuloma of Posterior Maxilla: First Expression of Primary Hyperparathyroidism

    Directory of Open Access Journals (Sweden)

    Deepanshu Gulati

    2015-01-01

    Full Text Available A case of 19-year-old male patient reported with the chief complaint of slowly growing diffuse painless swelling over the right part of the face from last 6 months. Intraoral examination revealed a swelling on right side of palate in relation to molar region with buccal cortical plate expansion. Radiographic examination (orthopantograph and 3DCT showed large multilocular radiolucency in right maxilla with generalized loss of lamina dura. Incisional biopsy was done and specimen was sent for histopathological examination which showed multinucleated giant cells containing 15–30 nuclei. Based on clinical, radiological, and histopathological findings provisional diagnosis of central giant cell granuloma was made. Blood tests after histopathology demonstrated elevated serum calcium level and alkaline phosphatase level. Immunoassay of parathyroid hormone (PTH level was found to be highly elevated. Radiographic examination of long bones like humerus and femur, mandible, and skull was also done which showed osteoclastic lesions. Considering the clinical, radiographic, histopathological, and blood investigation findings, final diagnosis of brown tumour of maxilla was made. The patient underwent partial parathyroidectomy under general anaesthesia to control primary hyperparathyroidism. Surgical removal of the bony lesion was done by curettage. The patient has been followed up for 1 year with no postoperative complications and the lesion healed uneventfully.

  7. Solitary ulcerated congenital giant juvenile xanthogranuloma

    Directory of Open Access Journals (Sweden)

    Su Yuen Ng

    2015-01-01

    Full Text Available A 3-month-old female patient with a giant ulcerated nodule over the back since birth was diagnosed as congenital giant juvenile xanthogranuloma (JXG based on clinical and histopathological examination. Congenital giant JXG with ulceration at birth is a rare presentation of JXG and commonly misdiagnosed. This case emphasizes the importance of being aware of the myriad presentations of JXG in order to make a correct diagnosis and avoid unnecessary investigations or treatment.

  8. Giant resonances in heavy-ion reactions

    International Nuclear Information System (INIS)

    Hussein, M.S.

    1982-11-01

    The several roles of multipole giant resonances in heavy-ion reactions are discussed. In particular, the modifications in the effective ion-ion potencial due to the virtual excitation of giant resonances at low energies, are considered and estimated for several systems. Real excitation of giant resonances in heavy-ion reactions at intermediate energies are then discussed and their importance in the approach phase of deeply inelastic processes in emphasized. Several demonstrative examples are given. (Author) [pt

  9. Miniature fibre optic probe for minimally invasive photoacoustic sensing

    Science.gov (United States)

    Mathews, Sunish J.; Zhang, Edward Z.; Desjardins, Adrien E.; Beard, Paul C.

    2016-03-01

    A miniature (175 μm) all-optical photoacoustic probe has been developed for minimally invasive sensing and imaging applications. The probe comprises a single optical fibre which delivers the excitation light and a broadband 50 MHz Fabry-Pérot (F-P) ultrasound sensor at the distal end for detecting the photoacoustic waves. A graded index lens proximal to the F-P sensor is used to reduce beam walk-off and thus increase sensitivity as well as confine the excitation beam in order to increase lateral spatial resolution. The probe was evaluated in non-scattering media and found to provide lateral and axial resolutions of < 100 μm and < 150 μm respectively for distances up to 1 cm from the tip of the probe. The ability of the probe to detect a blood vessel mimicking phantom at distances up to 7 mm from the tip was demonstrated in order to illustrate its potential suitability for needle guidance applications.

  10. Aesthetics of Islamic Miniature Art During the Periods of Safavid and ...

    African Journals Online (AJOL)

    Islamic art represents the spiritual and physical aspects in the lives of Muslims. Meaningful beauty in Islamic art expresses Islamic aesthetics. Islamic aesthetics is the connection between beauty and the sacred. The article is devoted to the Islamic art and miniature paintings of Timurid and Safavid periods in Iran. Miniature ...

  11. A locking compression plate versus the gold-standard non-locking plate with lag screw for first metatarsophalangeal fusion: A biomechanical comparison.

    Science.gov (United States)

    Mandell, Daniel; Karbassi, John; Zhou, Hanbing; Burroughs, Brian; Aurigemma, Philip; Patel, Abhay R

    2018-03-01

    The treatment of end-stage first metatarso-phalangeal joint (MTP) arthritis has been arthrodesis. A dorsal non-locking plate with a lag screw has been the standard traditional fixation method. This study compares the biomechanical strength of a locking compression plate (LCP) with and without internal compression versus this known gold standard. In group 1, six matched pairs of cadaver great toes were used to compare the standard non-locking dorsal plate and 3.5mm lag screw to an anatomic locking compression plate in which a lag screw was utilized rather than the internal compression features of the plate. In group 2, another six matched pairs of cadaver great toes were used to compare the gold standard to the locking compression plate, utilizing the plate's internal compression feature instead of a lag screw. A material testing system (MTS) machine applied loads to the MTP joints and measured displacement and stiffness of the constructs. The stiffness of the constructs (Young's modulus) was calculated from the force-displacement curves, and the displacement was measured. The locking compression plate group that used the compression features of the plate, without the lag screw, had less joint displacement and higher stiffness than control (p<0.05). The same plating construct in which a lag screw was used rather than internal compression of the plate was found to be stiffer than the control (p<0.05), but displacement was not statistically significant. The results suggest that a locking compression plate alone provides the stiffest construct for a first MTP joint fusion. Copyright © 2017 Elsevier Ltd. All rights reserved.

  12. Airtight miniaturized chromatography: a safer method for radiopharmaceutical quality control

    International Nuclear Information System (INIS)

    Coupal, J.J.; Shih, W.J.; Ryo, U.Y.

    1988-01-01

    Miniaturized chromatography is widely used for quality control of radiopharmaceuticals. Recently, published chromatography procedures have illustrated or described chromatography chambers open to the air in use, suggesting that volatile toxic mobile phases are harmless to people in the vicinity. The authors describe the results of their search for an inexpensive closed chromatography chamber that can be used to derive safely the benefits from conventional miniaturized chromatography

  13. Swiss roll operation for giant fibroadenoma.

    Science.gov (United States)

    Soomro, Saleem A; Memon, Sohail A; Mohammad, Noor; Maher, Mumtaz

    2009-01-01

    Fibroadenoma 5 cm or more is called giant fibroadenoma. Giant fibroadenoma can distort the shape of breast and causes asymmetry, so it should be excised. There are several techniques for excision of giant fibroadenoma. In our technique we remove them through cosmetically acceptable circumareolar incision to maintain the shape and symmetry of breast. The objectives were to assess the cosmetic results of Swiss roll operation for giant fibroadenoma. The study was conducted for six years from January, 2002 to December, 2007. Seventy patients of giant fibroadenoma were included in this study. They were diagnosed on history and clinical examination supported by ultrasound and postoperative histopathological examination. Data were collected from outpatient department and operation theatre. Swiss roll operation was performed under general anaesthesia. Mean tumor size was 6.38 cm. Three cm and 4 cm incisions were used for tumour 6 cm in size respectively. Skin closed with Vicryl 3/0 subcuticular stitches. Sixteen out of 70 patients had no scar while others hadminimal scar. All patients had normal shape and symmetry of breast. On histopathology fibroadenoma was confirmed. Giant fibroadenoma should be removed through cosmetically acceptable cicumareolar incision especially in unmarried young females who have small breast. Swiss-roll operation is superior in maintaining the shape and symmetry of breast. No major complication was found in our series except seroma formation in 10 patients.

  14. Giant serpentine intracranial aneurysm: a case report

    International Nuclear Information System (INIS)

    Park, Jae Seong; Lee, Myeong Sub; Kim, Myung Soon; Kim, Dong Jin; Park, Joong Wha; Whang, Kum

    2001-01-01

    The authors present a case of giant serpentine aneurysm (a partially thrombosed aneurysm containing tortuous vascular channels with a separate entrance and outflow pathway). Giant serpentine aneurysms form a subgroup of giant intracranial aneurysms, distinct from saccular and fusiform varieties, and in this case, too, the clinical presentation and radiographic features of CT, MR imaging and angiography were distinct

  15. Low-power, miniature {sup 171}Yb ion clock using an ultra-small vacuum package

    Energy Technology Data Exchange (ETDEWEB)

    Jau, Y.-Y.; Schwindt, P. D. D. [Sandia National Laboratories, Albuquerque, New Mexico 87185 (United States); Partner, H. [Sandia National Laboratories, Albuquerque, New Mexico 87185 (United States); Center for Quantum Information and Control (CQuIC), Department of Physics and Astronomy, University of New Mexico, Albuquerque, New Mexico 87131 (United States); Prestage, J. D.; Kellogg, J. R.; Yu, N. [Jet Propulsion Laboratory, California Institute of Technology, Pasadena, California 91109 (United States)

    2012-12-17

    We report a demonstration of a very small microwave atomic clock using the 12.6 GHz hyperfine transition of the trapped {sup 171}Yb ions inside a miniature, completely sealed-off 3 cm{sup 3} ion-trap vacuum package. In the ion clock system, all of the components are highly miniaturized with low power consumption except the 369 nm optical pumping laser still under development for miniaturization. The entire clock, including the control electronics, consumes <300 mW. The fractional frequency instability of the miniature Yb{sup +} clock reaches the 10{sup -14} range after a few days of integration.

  16. Plate tectonics and planetary habitability: current status and future challenges.

    Science.gov (United States)

    Korenaga, Jun

    2012-07-01

    Plate tectonics is one of the major factors affecting the potential habitability of a terrestrial planet. The physics of plate tectonics is, however, still far from being complete, leading to considerable uncertainty when discussing planetary habitability. Here, I summarize recent developments on the evolution of plate tectonics on Earth, which suggest a radically new view on Earth dynamics: convection in the mantle has been speeding up despite its secular cooling, and the operation of plate tectonics has been facilitated throughout Earth's history by the gradual subduction of water into an initially dry mantle. The role of plate tectonics in planetary habitability through its influence on atmospheric evolution is still difficult to quantify, and, to this end, it will be vital to better understand a coupled core-mantle-atmosphere system in the context of solar system evolution. © 2012 New York Academy of Sciences.

  17. Giant Impacts on Earth-Like Worlds

    Science.gov (United States)

    Kohler, Susanna

    2016-05-01

    examine the collisional histories of Earth-like planets that form. Their goal is to understand if our solar systems formation and evolution is typical or unique.How Common Are Giant Impacts?Histogram of the total number of giant impacts received by the 164 Earth-like worlds produced in the authors fragmentation-inclusive simulations. [Quintana et al. 2016]The authors find that including fragmentation does not affect the final number of planets that are formed in the simulation (an average of 34 in each system, consistent with our solar systems terrestrial planet count). But when fragmentation is included, fewer collisions end in merger which results in typical accretion timescales roughly doubling. So the effects of fragmentation influence the collisional history of the system and the length of time needed for the final system to form.Examining the 164 Earth-analogs produced in the fragmentation-inclusive simulations, Quintana and collaborators find that impacts large enough to completely strip a planets atmosphere are rare; fewer than 1% of the Earth-like worlds experienced this.But giant impacts that are able to strip ~50% of an Earth-analogs atmosphere roughly the energy of the giant impact thought to have formed our Moon are more common. Almost all of the authors Earth-analogs experienced at least 1 giant impact of this size in the 2-Gyr simulation, and the average Earth-like world experienced ~3 such impacts.These results suggest that our planets impact history with the Moon-forming impact likely being the last giant impact Earth experienced is fairly typical for Earth-like worlds. The outcomes also indicate that smaller impacts that are still potentially life-threatening are much more common than bulk atmospheric removal. Higher-resolution simulations could be used to examine such smaller impacts.CitationElisa V. Quintana et al 2016 ApJ 821 126. doi:10.3847/0004-637X/821/2/126

  18. High Performance Miniature Bandpass Filters, Phase I

    Data.gov (United States)

    National Aeronautics and Space Administration — This proposal is submitted for developing low impedance, miniature bandpass RF frequency filter via MEMS technique, in applications of SMAP, Aquarius follow-on,...

  19. A Spectral Reconstruction Algorithm of Miniature Spectrometer Based on Sparse Optimization and Dictionary Learning.

    Science.gov (United States)

    Zhang, Shang; Dong, Yuhan; Fu, Hongyan; Huang, Shao-Lun; Zhang, Lin

    2018-02-22

    The miniaturization of spectrometer can broaden the application area of spectrometry, which has huge academic and industrial value. Among various miniaturization approaches, filter-based miniaturization is a promising implementation by utilizing broadband filters with distinct transmission functions. Mathematically, filter-based spectral reconstruction can be modeled as solving a system of linear equations. In this paper, we propose an algorithm of spectral reconstruction based on sparse optimization and dictionary learning. To verify the feasibility of the reconstruction algorithm, we design and implement a simple prototype of a filter-based miniature spectrometer. The experimental results demonstrate that sparse optimization is well applicable to spectral reconstruction whether the spectra are directly sparse or not. As for the non-directly sparse spectra, their sparsity can be enhanced by dictionary learning. In conclusion, the proposed approach has a bright application prospect in fabricating a practical miniature spectrometer.

  20. Tensile and Creep Testing of Sanicro 25 Using Miniature Specimens

    Science.gov (United States)

    Dymáček, Petr; Jarý, Milan; Dobeš, Ferdinand; Kloc, Luboš

    2018-01-01

    Tensile and creep properties of new austenitic steel Sanicro 25 at room temperature and operating temperature 700 °C were investigated by testing on miniature specimens. The results were correlated with testing on conventional specimens. Very good agreement of results was obtained, namely in yield and ultimate strength, as well as short-term creep properties. Although the creep rupture time was found to be systematically shorter and creep ductility lower in the miniature test, the minimum creep rates were comparable. The analysis of the fracture surfaces revealed similar ductile fracture morphology for both specimen geometries. One exception was found in a small area near the miniature specimen edge that was cut by electro discharge machining, where an influence of the steel fracture behavior at elevated temperature was identified. PMID:29337867

  1. Tensile and Creep Testing of Sanicro 25 Using Miniature Specimens.

    Science.gov (United States)

    Dymáček, Petr; Jarý, Milan; Dobeš, Ferdinand; Kloc, Luboš

    2018-01-16

    Tensile and creep properties of new austenitic steel Sanicro 25 at room temperature and operating temperature 700 °C were investigated by testing on miniature specimens. The results were correlated with testing on conventional specimens. Very good agreement of results was obtained, namely in yield and ultimate strength, as well as short-term creep properties. Although the creep rupture time was found to be systematically shorter and creep ductility lower in the miniature test, the minimum creep rates were comparable. The analysis of the fracture surfaces revealed similar ductile fracture morphology for both specimen geometries. One exception was found in a small area near the miniature specimen edge that was cut by electro discharge machining, where an influence of the steel fracture behavior at elevated temperature was identified.

  2. Development of stress correction formulae for heat formed steel plates

    Directory of Open Access Journals (Sweden)

    Hyung Kyun Lim

    2018-03-01

    Full Text Available The heating process such as line heating, triangular heating and so on is widely used in plate forming of shell plates found in bow and stern area of outer shell in a ship. Local shrinkage during heating process is main physical phenomenon used in plate forming process. As it is well appreciated, the heated plate undergoes the change in material and mechanical properties around heated area due to the harsh thermal process. It is, therefore, important to investigate the changes of physical and mechanical properties due to heating process in order to use them plate the design stage of shell plates. This study is concerned with the development of formula of plastic hardening constitutive equation for steel plate on which line heating is applied. In this study the stress correction formula for the heated plate has been developed based on the numerical simulation of tension test with varying plate thickness and heating speed through the regression analysis of multiple variable case. It has been seen the developed formula shows very good agreement with results of numerical simulation. This paper ends with usefulness of the present formula in examining the structural characteristic of ship's hull. Keywords: Heat input, Heat transfer analysis, Line heating, Shell plate, Stress correction, Thermo-elasto-plastic analysis

  3. Miniature specimen technology for postirradiation fatigue crack growth testing

    International Nuclear Information System (INIS)

    Mervyn, D.A.; Ermi, A.M.

    1979-01-01

    Current magnetic fusion reactor design concepts require that the fatigue behavior of candidate first wall materials be characterized. Fatigue crack growth may, in fact, be the design limiting factor in these cyclic reactor concepts given the inevitable presence of crack-like flaws in fabricated sheet structures. Miniature specimen technology has been developed to provide the large data base necessary to characterize irradiation effects on the fatigue crack growth behavior. An electrical potential method of measuring crack growth rates is employed on miniature center-cracked-tension specimens (1.27 cm x 2.54 cm x 0.061 cm). Results of a baseline study on 20% cold-worked 316 stainless steel, which was tested in an in-cell prototypic fatigue machine, are presented. The miniature fatigue machine is designed for low cost, on-line, real time testing of irradiated fusion candidate alloys. It will enable large scale characterization and development of candidate first wall alloys

  4. Stellar oscillations in planet-hosting giant stars

    Energy Technology Data Exchange (ETDEWEB)

    Hatzes, Artie P; Zechmeister, Mathias [Thueringer Landessternwarte, Sternwarte 5, D-07778 (Germany)], E-mail: artie@tls-tautenburg.de

    2008-10-15

    Recently a number of giant extrasolar planets have been discovered around giant stars. These discoveries are important because many of these giant stars have intermediate masses in the range 1.2-3 Msun. Early-type main sequence stars of this mass range have been avoided by radial velocity planet search surveys due the difficulty of getting the requisite radial velocity precision needed for planet discoveries. Thus, giant stars can tell us about planet formation for stars more massive than the sun. However, the determination of stellar masses for giant stars is difficult due to the fact that evolutionary tracks for stars covering a wide range of masses converge to the same region of the H-R diagram. We report here on stellar oscillations in three planet-hosting giant stars: HD 13189, {beta} Gem, and {iota} Dra. Precise stellar radial velocity measurements for these stars show variations whose periods and amplitudes are consistent with solar-like p-mode oscillations. The implied stellar masses for these objects based on the characteristics of the stellar oscillations are consistent with the predictions of stellar isochrones. An investigation of stellar oscillations in planet hosting giant stars offers us the possibility of getting an independent determination of the stellar mass for these objects which is of crucial importance for extrasolar planet studies.

  5. Giant nuclear resonances

    International Nuclear Information System (INIS)

    Snover, K.A.

    1989-01-01

    Giant nuclear resonances are elementary mods of oscillation of the whole nucleus, closely related to the normal modes of oscillation of coupled mechanical systems. They occur systematically in most if not all nuclei, with oscillation energies typically in the range 10-30 MeV. One of the best - known examples is the giant electric dipole (El) resonance, in which all the protons and all the neutrons oscillate with opposite phase, producing a large time - varying electric dipole moment which acts as an effective antenna for radiating gamma ray. This paper discusses this mode as well as quadrupole and monopole modes

  6. Serosurvey of Leptospirainterrogans, Brucellaabortus and Chlamydophilaabortus infection in free-ranging giant anteaters (Myrmecophaga tridactyla from Brazil

    Directory of Open Access Journals (Sweden)

    Flávia R. Miranda

    2015-05-01

    Full Text Available Abstract:A serological survey for antibodies against Leptospira interrogans, Brucella abortus, and Chlamydophila abortus was conducted in 21 clinically healthy, free-ranging giant ant- eaters (Myrmecophaga tridactyla from Parque Nacional das Emas (Goiás State, Brazil; n=6, Parque Nacional da Serra da Canastra (Minas Gerais State, Brazil; n=9, and RPPN SESC Pantanal (Mato Grosso State, Brazil; n=6 between July 2001 and September 2006. Sera were screened for antibodies against 22 serovars of Leptospira interrogans with a microscopic agglutination test. Twelve tested positive for L. interrogansserovars sentot (n=5 in PN Emas, n=2 in PN Serra da Canastra, butembo (n=2 in PN Serra da Canastra, autumnalis, bataviae, and shermani/icterohaemorrhagiae(n=1 each in SESC PantanalOne adult female tested positive for B. abortus with the buffered plate antigen test. All sera were negative for C. abortususing the complement fixation text. This is the first report of pathogens that may interfere with the reproduction and population dynamics of free-ranging giant anteaters.

  7. Modeling particulate removal in plate-plate and wire-plate electrostatic precipitators

    Directory of Open Access Journals (Sweden)

    S Ramechecandane

    2016-09-01

    Full Text Available The present study is concerned with the modeling of electrically charged particles in a model plate-plate and a single wire-plate electrostatic precipitator (ESP. The particle concentration distributions for both a plate-plate and a wire-plate ESP are calculated using a modified drift flux model. Numerical investigations are performed using the modified drift flux model for particle number concentration, in addition to the RNG k - ε model for the mean turbulent flow field and the Poisson equation for the electric field. The proposed model and the outlined methodology for coupling the flow field, electric field, charging kinetics and particle concentration is applied to two model precipitators that are truly representative of a wide class of commercialized ESPs. The present investigation is quite different from the earlier studies as it does not make assumptions like a homogeneous electric field or an infinite turbulent diffusivity. The electric field calculated is a strong function of position and controls the migration velocity of particles. Hence, the proposed model can be implemented in a flow solver to obtain a full-fledged solution for any kind of ESP with no limitations on the particle number concentration, as encountered in a Lagrangian approach. The effect of turbulent diffusivity on particle number concentration in a plate-plate ESP is investigated in detail and the results obtained are compared with available experimental data. Similarly, the effect of particle size/diameter and applied electric potential on the accumulative collection performance in the case of a wire-plate ESP is studied and the results obtained are compared with available numerical data. The numerical results obtained using the modified drift flux model for both the plate-plate and wire-plate ESP are in close agreement with available experimental and numerical data.

  8. Foundation plate on the elastic half-space, deterministic and probabilistic approach

    Directory of Open Access Journals (Sweden)

    Tvrdá Katarína

    2017-01-01

    Full Text Available Interaction between the foundation plate and subgrade can be described by different mathematical - physical model. Elastic foundation can be modelled by different types of models, e.g. one-parametric model, two-parametric model and a comprehensive model - Boussinesque (elastic half-space had been used. The article deals with deterministic and probabilistic analysis of deflection of the foundation plate on the elastic half-space. Contact between the foundation plate and subsoil was modelled using contact elements node-node. At the end the obtained results are presented.

  9. Measuring Precise Radii of Giants Orbiting Giants to Distinguish Between Planet Evolution Models

    Science.gov (United States)

    Grunblatt, Samuel; Huber, Daniel; Lopez, Eric; Gaidos, Eric; Livingston, John

    2017-10-01

    Despite more than twenty years since the initial discovery of highly irradiated gas giant planets, the mechanism for planet inflation remains unknown. However, proposed planet inflation mechanisms can now be separated into two general classes: those which allow for post-main sequence planet inflation by direct irradiation from the host star, and those which only allow for slowed cooling of the planet over its lifetime. The recent discovery of two inflated warm Jupiters orbiting red giant stars with the NASA K2 Mission allows distinction between these two classes, but uncertainty in the planet radius blurs this distinction. Observing transits of these planets with the Spitzer Space Telescope would reduce stellar variability and thus planet radius uncertainties by approximately 50% relative to K2, allowing distinction between the two planet inflation model classes at a 3-sigma level. We propose to observe one transit of both known warm Jupiters orbiting red giant stars, K2-97b and EPIC228754001.01, to distinguish between planet model inflation classes and measure the planetary heating efficiency to 3-sigma precision. These systems are benchmarks for the upcoming NASA TESS Mission, which is predicted to discover an order of magnitude more red giant planet systems after launching next year.

  10. PERFORMANCE ENHANCEMENT OF A MINIATURE STIRLING CRYOCOOLER WITH A MULTI MESH REGENERATOR DESIGN

    Directory of Open Access Journals (Sweden)

    KISHOR KUMAR V. V.

    2017-06-01

    Full Text Available A parametric study has been carried out using the software REGEN 3.3 to optimize the regenerator of a miniature Stirling cryocooler operating with a warm end temperature of 300 K and cold end temperature of 80 K. Regenerator designs which produce the maximum coefficient of performance (COP of the system is considered as an optimized regenerator. The length and diameter of the regenerator were fixed from the cooler system requirements. Single mesh regenerators made of 200, 250, 300, 400 and 450 Stainless Steel wire meshes were considered and the optimum phase angle and mesh size were obtained. A maximum COP of 0.1475 was obtained for 300 mesh regenerator at 70° phase angle. Then multi mesh regenerators were considered with finer mesh on the cold end and coarser mesh on the hot end. The optimum size and length of each mesh in the multi mesh regenerator and the optimum phase angle were calculated. The maximum COP of 0.156 was obtained for 200 300-400 multi mesh regenerator at 70° phase angle. The COP and net refrigeration obtained for an optimized multi mesh regenerator was found to be significantly higher than that of a single mesh regenerator. Thus a multi mesh regenerator design with a proper combination of regenerator mesh size and length can enhance the regenerator effectiveness.

  11. Thermal resistance of a convectively cooled plate with applied heat flux and variable internal heat generation

    International Nuclear Information System (INIS)

    Venkataraman, N.S.; Cardoso, H.P.; Oliveira Filho, O.B. de

    1981-01-01

    The conductive heat transfer in a rectangular plate with nonuniform internal heat generation, with one end convectively cooled and a part of the opposite end subjected to external heat flux is considered. The remaining part of this end as well as the other two sides are thermally insulated. The governing differential equation is solved by a finite difference scheme. The variation of the thermal resistance with Biot modulus, the plate geometry, the internal heat generation parameter and the type of profile of internal heat generation is discussed. (author) [pt

  12. Procedure and device for extracting the end of a tube inserted into a hole in a tube plate

    International Nuclear Information System (INIS)

    1980-01-01

    When constructing heat exchangers and steam generators, particularly in the construction of steam generators for nuclear power stations, many small diameter tubes have to be secured into a very thick tube plate for instance 600 mm thick. This crimping or expanding of the tube is generally performed by rolling the internal surface of the tube inside a hole drilled right through the tube plate and slightly greater in diameter than the external diameter of the tube before the tube is rolled. To check the tubes for defects, it is necessary to extract certain tubes from the tube plate in order to move the tube to a testing and inspection point and examine the part of it that was secured in the plate hole. The invention concerns the uncrimping of these tubes [fr

  13. Sensitivity of Miniaturized Photo-elastic Transducer for Small Force Sensing

    Directory of Open Access Journals (Sweden)

    Naceur-Eddine KHELIFA

    2015-01-01

    Full Text Available The sensitivity of a force sensor based on photo-elastic effect in a monolithic Nd- YAG laser depends strongly on the geometrical shape and dimensions of the laser medium. The theoretical predictions of sensitivity are in good agreement with first results obtained with a plano- concave cylindrical crystal of (4´4 mm and some values reported by other groups. However, for small size of the laser sensor, the developed model predicts sensitivity, about 30 % higher than the values given by available experiments. In this paper, we present experimental results obtained with a force sensor using a miniaturized monolithic cylindrical Nd-YAG laser of dimensions (2´3 mm with suitable optical coatings on its plane end faces. The new result of measurement concerning the sensitivity has allowed us to refine the theoretical model to treat photo-elastic force sensors with small dimensions.

  14. End effect Keff bias curve for actinide-only burnup credit casks

    International Nuclear Information System (INIS)

    Kang, C.H.; Lancaster, D.B.

    1997-01-01

    A conservative end effect k eff bias curve for actinide-only burnup credit for spent fuel casks is presented in this paper. The k eff bias values can be added to the uniform axial burnup analysis to conservatively bound the actinide-only end effect. A normalized axial burnup distribution for the standard Westinghouse 17 x 17 assembly design is used for calculating k eff . The end effect calculated is a strong function of burnup, and increases as cask size size decreases. The presence of poison plates increases the end effect. The bias curve presented is based on the most limiting cask configuration of a single PWR assembly with completely black poison plates. Therefore, axially uniform criticality calculations with application of the proposed k eff could eliminate the need for axially burnup dependent analyses. 7 refs., 1 fig

  15. Miniature and micro mass spectrometry for nanoscale sensing applications

    International Nuclear Information System (INIS)

    Taylor, S; France, N

    2009-01-01

    In recent years the use of miniature and/or microscale versions of the more popular mass spectrometers have been realised. This has led to the development of portable analytical devices for a range of 'in the field' sensing applications in aerospace, environmental monitoring, medical diagnosis and process control. In this paper the principles underpinning the development of miniature quadrupole mass spectrometers are reviewed. Two different microfabrication methods are compared with a conventional QMS used for residual gas analysis in the range 1-100 Da.

  16. EMC, RF, and Antenna Systems in Miniature Electronic Devices

    DEFF Research Database (Denmark)

    Ruaro, Andrea

    Advanced techniques for the control of electromagnetic interference (EMI) and for the optimization of the electromagnetic compatibility (EMC) performance has been developed under the constraints typical of miniature electronic devices (MED). The electromagnetic coexistence of multiple systems....... The structure allows for effective suppression of radiation from the MED, while taking into consideration the integration and miniaturization aspects. To increase the sensitivity of the system, a compact LNA suitable for on-body applications has been developed. The LNA allows for an increase in the overall...

  17. Determination of giant resonance strengths

    International Nuclear Information System (INIS)

    Serr, F.E.

    1983-01-01

    Using theoretical strength functions to describe the different giant resonances expected at excitation energies of the order of (60-85)/Asup(1/3) MeV, we calculate the double differential cross sections d 2 sigma/dΩ dE associated with the reactions 208 Pb(α, α') and 90 Zr(α, α') (Esub(α) = 152 MeV). The angular distributions for the giant quadrupole and giant monopole resonances obtained from fits to these spectra, making simple, commonly used assumptions for the peak shapes and background, are compared to the original angular distributions. The differences between them are an indication of some of the uncertainties affecting the giant resonance strengths extracted from hadron inelastic scattering data. Fits to limited angular regions lead to errors of up to 50% in the value of the energy-weighted sum rule, depending on the angles examined. While it seems possible to extract the correct EWSR for the GMR by carrying out the analyses at 0 0 , no single privileged angle seems to exist in the case of the GQR. (orig.)

  18. A Spectral Reconstruction Algorithm of Miniature Spectrometer Based on Sparse Optimization and Dictionary Learning

    Science.gov (United States)

    Zhang, Shang; Fu, Hongyan; Huang, Shao-Lun; Zhang, Lin

    2018-01-01

    The miniaturization of spectrometer can broaden the application area of spectrometry, which has huge academic and industrial value. Among various miniaturization approaches, filter-based miniaturization is a promising implementation by utilizing broadband filters with distinct transmission functions. Mathematically, filter-based spectral reconstruction can be modeled as solving a system of linear equations. In this paper, we propose an algorithm of spectral reconstruction based on sparse optimization and dictionary learning. To verify the feasibility of the reconstruction algorithm, we design and implement a simple prototype of a filter-based miniature spectrometer. The experimental results demonstrate that sparse optimization is well applicable to spectral reconstruction whether the spectra are directly sparse or not. As for the non-directly sparse spectra, their sparsity can be enhanced by dictionary learning. In conclusion, the proposed approach has a bright application prospect in fabricating a practical miniature spectrometer. PMID:29470406

  19. CMB lensing and giant rings

    Energy Technology Data Exchange (ETDEWEB)

    Rathaus, Ben; Itzhaki, Nissan, E-mail: nitzhaki@post.tau.ac.il, E-mail: ben.rathaus@gmail.com [Raymond and Beverly Sackler Faculty of Exact Sciences, School of Physics and Astronomy, Tel-Aviv University, Ramat-Aviv, 69978 (Israel)

    2012-05-01

    We study the CMB lensing signature of a pre-inationary particle (PIP), assuming it is responsible for the giant rings anomaly that was found recently in the WMAP data. Simulating Planck-like data we find that generically the CMB lensing signal to noise ratio associated with such a PIP is quite small and it would be difficult to cross correlate the temperature giant rings with the CMB lensing signal. However, if the pre-inationary particle is also responsible for the bulk flow measured from the local large scale structure, which happens to point roughly at the same direction as the giant rings, then the CMB lensing signal to noise ratio is fairly significant.

  20. Production of quartz plates for CMS-CASTOR Experiment

    CERN Document Server

    Adiguzel, Aytul; Ayhan, Aydin; Bakirci, Mustafa Numan; Basegmez, Suzan; Beaumont, Willem; Borras, Kerstin; Campbell, Alan; De Paula Carvalho, W; Çerçi, Salim; De Jesus Damiao, Dilson; Dogangün, O; Dumanoglu, Isa; d'Enterria, David; Erchov, Y; Eskut, Eda; Figueiredo, D; Girgis, Semiray; Göttlicher, P; Gouskos, Loukas; Gurpinar, Emine; Hos, Ilknur; Katkov, Igor; Katsas, Panagiotis; Khein, Lev; Knutsson, Albert; Kuznetsov, Andrey; Lebeau, Michel; Van Mechelen, Pierre; Muhl, Carsten; Musienko, Yuri; Ochesanu, Silvia; Onengüt, G; Onengut, G Jr; Ozdemir, Kadri; Panagiotou, Apostolos; Polatoz, A; Ripert, Marion; Shileev, K; Sogut, Kenan; Tiflov, B TaliV; Kayis-Topaksu, A; Uzun, Dilber

    2008-01-01

    Light transmission rate performance of $102$ irradiated quartz samples was measured to select the best quartz plates for CMS-CASTOR calorimeter. All the produced quartz plates were originally used in a previous CERN experiment, DELPHI. Three different doses of $^{60}$Co source were used with the collaboration of PSI (Paul Scherrer Institute, Villigen PSI, Switzerland.) to study the transmission rate performance of the quartz samples after irradiation for different incident light, ranging from $250$ to $700$ nm in $5$ nm increasing steps. All samples show different decrease in the rate with wavelength for different doses. Three different steps were followed before irradiation to find out the best way of cleaning the original DELPHI Cu/Cr tracks on the samples. Results of these measurements presented here correspond to the quartz plates that will be used in one hadronic sector of CASTOR calorimeter until end of 2008. For the full calorimeter new quartz plates will be installed. We also present the light transmi...

  1. Plasma Structure and Behavior of Miniature Ring-Cusp Discharges

    Science.gov (United States)

    Mao, Hann-Shin

    Miniature ring-cusp ion thrusters provide a unique blend of high efficiencies and millinewton level thrust for future spacecraft. These thrusters are attractive as a primary propulsion for small satellites that require a high delta V, and as a secondary propulsion for larger spacecraft that require precision formation flying, disturbance rejection, or attitude control. To ensure desirable performance throughout the life of such missions, an advancement in the understanding of the plasma structure and behavior of miniature ring-cusp discharges is required. A research model was fabricated to provide a simplified experimental test bed for the analysis of the plasma discharge chamber of a miniature ion thruster. The plasma source allowed for spatially resolved measurements with a Langmuir probe along a meridian plane. Probe measurements yielded plasma density, electron temperature, and plasma potential data. The magnetic field strength was varied along with the discharge current to determine the plasma behavior under various conditions. The structure of the plasma properties were found to be independent of the discharge power under the proper scaling. It was concluded that weaker magnetic fields can improve the overall performance for ion thruster operation. To further analyze the experimental measurements, a framework was developed based on the magnetic field. A flux aligned coordinate system was developed to decouple the perpendicular and parallel plasma motion with respect to the magnetic field. This was done using the stream function and magnetic scalar potential. Magnetic formulae provided intuition on the field profiles dependence on magnet dimensions. The flux aligned coordinate system showed that the plasma was isopycnic along constant stream function values. This was used to develop an empirical relation suitable for estimating the spatial behavior and to determine the plasma volume and loss areas. The plasma geometry estimates were applied to a control volume

  2. A miniature X-ray tube based on carbon nanotube for an intraoral dental radiography

    International Nuclear Information System (INIS)

    Kim, Hyun Jin; Park, Han Beom; Lee, Ju Hyuk; Cho, Sung Oh

    2016-01-01

    The number of human teeth that can be radiographically taken is limited. Moreover, at least two X-ray shots are required to get images of teeth from both sides of the mouth. In order to overcome the disadvantages of conventional dental radiography, a dental radiograph has been proposed in which an X-ray tube is inserted into the mouth while an X-ray detector is placed outside the mouth. The miniature X-ray tube is required small size to insert into the mouth. Recently, we have fabricated a miniature x-ray tube with the diameter of 7 mm using a carbon nanotube (CNT) field. But, commercialized miniature X-ray tube were adopted a thermionic type using tungsten filament. The X-ray tubes adopted thermionic emission has a disadvantage of increasing temperature of x-ray tube. So it need to cooling system to cool x-ray tube. On the other hands, X-ray tubes adopted CNT field emitters don't need cooling systems because electrons are emitted from CNT by applying high voltage without heating. We have developed the miniature x-ray tube that produce x-ray with uniform spatial distribution based on carbon nanotube field emitters. The fabricated miniature x-ray tube can be stably and reliably operated at 50kV without any vacuum pump. The developed miniature X-ray tube was applied for intraoral dental radiography that employs an intra-oral CNT-based miniature X-ray tube and extra-oral X-ray detectors. An X-ray image of many teeth was successfully obtained by a single X-ray shot using the intra-oral miniature X-ray tube system. Furthermore, images of both molar teeth of pig were simultaneously obtained by a single X-ray shot. These results show that the intraoral dental radiography, which employs an intraoral miniature X-ray tube and an extraoral X-ray detector, performs better than conventional dental radiography

  3. A miniature X-ray tube based on carbon nanotube for an intraoral dental radiography

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Hyun Jin; Park, Han Beom; Lee, Ju Hyuk; Cho, Sung Oh [KAIST, Daejeon (Korea, Republic of)

    2016-05-15

    The number of human teeth that can be radiographically taken is limited. Moreover, at least two X-ray shots are required to get images of teeth from both sides of the mouth. In order to overcome the disadvantages of conventional dental radiography, a dental radiograph has been proposed in which an X-ray tube is inserted into the mouth while an X-ray detector is placed outside the mouth. The miniature X-ray tube is required small size to insert into the mouth. Recently, we have fabricated a miniature x-ray tube with the diameter of 7 mm using a carbon nanotube (CNT) field. But, commercialized miniature X-ray tube were adopted a thermionic type using tungsten filament. The X-ray tubes adopted thermionic emission has a disadvantage of increasing temperature of x-ray tube. So it need to cooling system to cool x-ray tube. On the other hands, X-ray tubes adopted CNT field emitters don't need cooling systems because electrons are emitted from CNT by applying high voltage without heating. We have developed the miniature x-ray tube that produce x-ray with uniform spatial distribution based on carbon nanotube field emitters. The fabricated miniature x-ray tube can be stably and reliably operated at 50kV without any vacuum pump. The developed miniature X-ray tube was applied for intraoral dental radiography that employs an intra-oral CNT-based miniature X-ray tube and extra-oral X-ray detectors. An X-ray image of many teeth was successfully obtained by a single X-ray shot using the intra-oral miniature X-ray tube system. Furthermore, images of both molar teeth of pig were simultaneously obtained by a single X-ray shot. These results show that the intraoral dental radiography, which employs an intraoral miniature X-ray tube and an extraoral X-ray detector, performs better than conventional dental radiography.

  4. Miniaturized Aptamer-Based Assays for Protein Detection

    Directory of Open Access Journals (Sweden)

    Alessandro Bosco

    2016-09-01

    Full Text Available The availability of devices for cancer biomarker detection at early stages of the disease is one of the most critical issues in biomedicine. Towards this goal, to increase the assay sensitivity, device miniaturization strategies empowered by the employment of high affinity protein binders constitute a valuable approach. In this work we propose two different surface-based miniaturized platforms for biomarker detection in body fluids: the first platform is an atomic force microscopy (AFM-based nanoarray, where AFM is used to generate functional nanoscale areas and to detect biorecognition through careful topographic measurements; the second platform consists of a miniaturized electrochemical cell to detect biomarkers through electrochemical impedance spectroscopy (EIS analysis. Both devices rely on robust and highly-specific protein binders as aptamers, and were tested for thrombin detection. An active layer of DNA-aptamer conjugates was immobilized via DNA directed immobilization on complementary single-stranded DNA self-assembled monolayers confined on a nano/micro area of a gold surface. Results obtained with these devices were compared with the output of surface plasmon resonance (SPR assays used as reference. We succeeded in capturing antigens in concentrations as low as a few nM. We put forward ideas to push the sensitivity further to the pM range, assuring low biosample volume (μL range assay conditions.

  5. Microsupercapacitors as miniaturized energy-storage components for on-chip electronics

    Science.gov (United States)

    Kyeremateng, Nana Amponsah; Brousse, Thierry; Pech, David

    2017-01-01

    The push towards miniaturized electronics calls for the development of miniaturized energy-storage components that can enable sustained, autonomous operation of electronic devices for applications such as wearable gadgets and wireless sensor networks. Microsupercapacitors have been targeted as a viable route for this purpose, because, though storing less energy than microbatteries, they can be charged and discharged much more rapidly and have an almost unlimited lifetime. In this Review, we discuss the progress and the prospects of integrated miniaturized supercapacitors. In particular, we discuss their power performances and emphasize the need of a three-dimensional design to boost their energy-storage capacity. This is obtainable, for example, through self-supported nanostructured electrodes. We also critically evaluate the performance metrics currently used in the literature to characterize microsupercapacitors and offer general guidelines to benchmark performances towards prospective applications.

  6. Role of nature reserves in giant panda protection.

    Science.gov (United States)

    Kang, Dongwei; Li, Junqing

    2018-02-01

    Giant panda (Ailuropoda melanoleuca) is a flagship species in nature conservation of the world; to protect this species, 67 nature reserves have been established in China. To evaluate the protection effect of giant panda nature reserves, we analyzed the variation of giant panda number and habitat area of 23 giant panda nature reserves of Sichuan province based on the national survey data released by State Forestry Administration and Sichuan Forestry Department. Results showed that from the third national survey to the fourth, giant panda number and habitat area of 23 giant panda nature reserves of Sichuan province failed to realize the significant increase. Furthermore, we found that the total population growth rate of 23 nature reserves in the last 12 years was lower than those of the province total of Sichuan and the national total of China, and the total habitat area of the 23 nature reserves was decreasing in the last 12 years, but the province total and national total were all increasing. We propose that giant panda protection should pay more attention to how to improve the protective effects of nature reserves.

  7. Miniature Active Space Radiation Dosimeter, Phase II

    Data.gov (United States)

    National Aeronautics and Space Administration — Space Micro will extend our Phase I R&D to develop a family of miniature, active space radiation dosimeters/particle counters, with a focus on biological/manned...

  8. Modeling Impacts of Climate Change on Giant Panda Habitat

    Directory of Open Access Journals (Sweden)

    Melissa Songer

    2012-01-01

    Full Text Available Giant pandas (Ailuropoda melanoleuca are one of the most widely recognized endangered species globally. Habitat loss and fragmentation are the main threats, and climate change could significantly impact giant panda survival. We integrated giant panda habitat information with general climate models (GCMs to predict future geographic distribution and fragmentation of giant panda habitat. Results support a major general prediction of climate change—a shift of habitats towards higher elevation and higher latitudes. Our models predict climate change could reduce giant panda habitat by nearly 60% over 70 years. New areas may become suitable outside the current geographic range but much of these areas is far from the current giant panda range and only 15% fall within the current protected area system. Long-term survival of giant pandas will require the creation of new protected areas that are likely to support suitable habitat even if the climate changes.

  9. Miniaturized radiation chirper

    International Nuclear Information System (INIS)

    Umbarger, C.J.; Wolf, M.A.

    1980-01-01

    A miniaturized radiation chirper for use with a small battery supplying on the order of 5 volts is described. A poor quality CdTe crystal which is not necessarily suitable for high resolution gamma ray spectroscopy is incorporated with appropriate electronics so that the chirper emits an audible noise at a rate that is proportional to radiation exposure level. The chirper is intended to serve as a personnel radiation warning device that utilizes new and novel electronics with a novel detector, a CdTe crystal. The resultant device is much smaller and has much longer battery life than existing chirpers

  10. Tsunami Numerical Simulation for Hypothetical Giant or Great Earthquakes along the Izu-Bonin Trench

    Science.gov (United States)

    Harada, T.; Ishibashi, K.; Satake, K.

    2013-12-01

    We performed tsunami numerical simulations from various giant/great fault models along the Izu-Bonin trench in order to see the behavior of tsunamis originated in this region and to examine the recurrence pattern of great interplate earthquakes along the Nankai trough off southwest Japan. As a result, large tsunami heights are expected in the Ryukyu Islands and on the Pacific coasts of Kyushu, Shikoku and western Honshu. The computed large tsunami heights support the hypothesis that the 1605 Keicho Nankai earthquake was not a tsunami earthquake along the Nankai trough but a giant or great earthquake along the Izu-Bonin trench (Ishibashi and Harada, 2013, SSJ Fall Meeting abstract). The Izu-Bonin subduction zone has been regarded as so-called 'Mariana-type subduction zone' where M>7 interplate earthquakes do not occur inherently. However, since several M>7 outer-rise earthquakes have occurred in this region and the largest slip of the 2011 Tohoku earthquake (M9.0) took place on the shallow plate interface where the strain accumulation had considered to be a little, a possibility of M>8.5 earthquakes in this region may not be negligible. The latest M 7.4 outer-rise earthquake off the Bonin Islands on Dec. 22, 2010 produced small tsunamis on the Pacific coast of Japan except for the Tohoku and Hokkaido districts and a zone of abnormal seismic intensity in the Kanto and Tohoku districts. Ishibashi and Harada (2013) proposed a working hypothesis that the 1605 Keicho earthquake which is considered a great tsunami earthquake along the Nankai trough was a giant/great earthquake along the Izu-Bonin trench based on the similarity of the distributions of ground shaking and tsunami of this event and the 2010 Bonin earthquake. In this study, in order to examine the behavior of tsunamis from giant/great earthquakes along the Izu-Bonin trench and check the Ishibashi and Harada's hypothesis, we performed tsunami numerical simulations from fault models along the Izu-Bonin trench

  11. Miniaturized integration of a fluorescence microscope

    Science.gov (United States)

    Ghosh, Kunal K.; Burns, Laurie D.; Cocker, Eric D.; Nimmerjahn, Axel; Ziv, Yaniv; Gamal, Abbas El; Schnitzer, Mark J.

    2013-01-01

    The light microscope is traditionally an instrument of substantial size and expense. Its miniaturized integration would enable many new applications based on mass-producible, tiny microscopes. Key prospective usages include brain imaging in behaving animals towards relating cellular dynamics to animal behavior. Here we introduce a miniature (1.9 g) integrated fluorescence microscope made from mass-producible parts, including semiconductor light source and sensor. This device enables high-speed cellular-level imaging across ∼0.5 mm2 areas in active mice. This capability allowed concurrent tracking of Ca2+ spiking in >200 Purkinje neurons across nine cerebellar microzones. During mouse locomotion, individual microzones exhibited large-scale, synchronized Ca2+ spiking. This is a mesoscopic neural dynamic missed by prior techniques for studying the brain at other length scales. Overall, the integrated microscope is a potentially transformative technology that permits distribution to many animals and enables diverse usages, such as portable diagnostics or microscope arrays for large-scale screens. PMID:21909102

  12. A miniaturized electrochemical toxicity biosensor based on graphene oxide quantum dots/carboxylated carbon nanotubes for assessment of priority pollutants.

    Science.gov (United States)

    Zhu, Xiaolin; Wu, Guanlan; Lu, Nan; Yuan, Xing; Li, Baikun

    2017-02-15

    The study presented a sensitive and miniaturized cell-based electrochemical biosensor to assess the toxicity of priority pollutants in the aquatic environment. Human hepatoma (HepG2) cells were used as the biological recognition agent to measure the changes of electrochemical signals and reflect the cell viability. The graphene oxide quantum dots/carboxylated carbon nanotubes hybrid was developed in a facile and green way. Based on the hybrid composite modified pencil graphite electrode, the cell culture and detection vessel was miniaturized to a 96-well plate instead of the traditional culture dish. In addition, three sensitive electrochemical signals attributed to guanine/xanthine, adenine, and hypoxanthine were detected simultaneously. The biosensor was used to evaluate the toxicity of six priority pollutants, including Cd, Hg, Pb, 2,4-dinitrophenol, 2,4,6-trichlorophenol, and pentachlorophenol. The 24h IC 50 values obtained by the electrochemical biosensor were lower than those of conventional MTT assay, suggesting the enhanced sensitivity of the electrochemical assay towards heavy metals and phenols. This platform enables the label-free and sensitive detection of cell physiological status with multi-parameters and constitutes a promising approach for toxicity detection of pollutants. It makes possible for automatical and high-throughput analysis on nucleotide catabolism, which may be critical for life science and toxicology. Copyright © 2016 Elsevier B.V. All rights reserved.

  13. A High-Mass Cold Core in the Auriga-California Giant Molecular Cloud

    Science.gov (United States)

    Magnus McGehee, Peregrine; Paladini, Roberta; Pelkonen, Veli-Matti; Toth, Viktor; Sayers, Jack

    2015-08-01

    The Auriga-California Giant Molecular Cloud is noted for its relatively low star formation rate, especially at the high-mass end of the Initial Mass Function. We combine maps acquired by the Caltech Submillimeter Observatory's Multiwavelength Submillimeter Inductance Camera [MUSIC] in the wavelength range 0.86 to 2.00 millimeters with Planck and publicly-available Herschel PACS and SPIRE data in order to characterize the mass, dust properties, and environment of the bright core PGCC G163.32-8.41.

  14. Magnetocaloric effect and corrosion resistance of La(Fe, Si)13 composite plates bonded by different fraction of phenolic resin

    Science.gov (United States)

    Zhang, K. S.; Xue, J. N.; Wang, Y. X.; Sun, H.; Long, Y.

    2018-04-01

    La(Fe, Si)13-based composite plates were successfully fabricated using different amount of phenolic resin. The introduction of phenolic resin as binder increased the corrosion resistance and maintained giant magnetocaloric effect for La(Fe, Si)13-based composite plates. It was found that corroded spots were firstly observed on the boundaries between resin and La(Fe, Si)13 particles, rather than in La(Fe, Si)13-based particles, after being immersed in static distilled water. The corrosion rate decreased significantly with the increase of resin content. And the increase of the content of phenolic resin leads to the reduction of corrosion current density. Meanwhile, the volumetric magnetic entropy change ΔSM decreases slightly as the content of phenolic resin increases. The ΔSM of the plates with 3 wt.%, 5 wt.% and 8 wt.% resin are 63.1, 61.2 and 59.8 mJ/cm3 K under a low magnetic field change of 1 T, respectively.

  15. Giant lobelias exemplify convergent evolution

    Directory of Open Access Journals (Sweden)

    Givnish Thomas J

    2010-01-01

    Full Text Available Abstract Giant lobeliads on tropical mountains in East Africa and Hawaii have highly unusual, giant-rosette growth forms that appear to be convergent on each other and on those of several independently evolved groups of Asteraceae and other families. A recent phylogenetic analysis by Antonelli, based on sequencing the widest selection of lobeliads to date, raises doubts about this paradigmatic example of convergent evolution. Here I address the kinds of evidence needed to test for convergent evolution and argue that the analysis by Antonelli fails on four points. Antonelli's analysis makes several important contributions to our understanding of lobeliad evolution and geographic spread, but his claim regarding convergence appears to be invalid. Giant lobeliads in Hawaii and Africa represent paradigmatic examples of convergent evolution.

  16. Orbital maneuvering vehicle end effectors

    Science.gov (United States)

    Myers, W. Neill (Inventor); Forbes, John C. (Inventor); Barnes, Wayne L. (Inventor)

    1988-01-01

    An end effector device (A) for grasping and holding an article such as a handle (18) of a space telescope is disclosed. The device includes a V-shaped capture window (74) defined as inclined surfaces (76, 78) in parallel face plates (22, 24) which converge toward a retainer recess (54) in which the handle is retained. A pivotal finger (30) meshes with a pair of pivoted fingers (26, 28) which rotate in counterrotation. The fingers rotate to pull a handle within the capture window into recess (54) where latches (50) lock handle (18) in the recess. To align the capture window, plates (22, 24) may be cocked plus or minus five degrees on base (64).

  17. Surgical treatment for giant incisional hernia

    DEFF Research Database (Denmark)

    Eriksson, A; Rosenberg, J; Bisgaard, T

    2014-01-01

    INTRODUCTION: Repair for giant incisional hernias is a challenge due to unacceptable high morbidity and recurrence rates. Several surgical techniques are available, but all are poorly documented. This systematic review was undertaken to evaluate the existing literature on repair for giant...... % with a wide range between studies of 4-100 %. The mortality ranged from 0 to 5 % (median 0 %) and recurrence rate ranged from 0 to 53 % (median 5 %). Study follow-up ranged from 15 to 97 months (median 36 months). Mesh repair should always be used for patients undergoing repair for a giant hernia......, and the sublay position may have advantages over onlay positioning. To avoid tension, it may be advisable to use a mesh in combination with a component separation technique. Inlay positioning of the mesh and repair without a mesh should be avoided. CONCLUSIONS: Evidence to optimise repair for giant hernias...

  18. Experimental and numerical study of the wave run-up along a vertical plate

    DEFF Research Database (Denmark)

    Molin, Bernard; Kimmoun, O.; Liu, Y.

    2010-01-01

    Results from experiments on wave interaction with a rigid vertical plate are reported. The 5m long plate is set against the wall of a 30m wide basin, at 100m from the wavemaker. This set-up is equivalent to a 10m plate in the middle of a 60m wide basin. Regular waves are produced, with wavelength...... on extended Boussinesq equations. In most of the experimental tests, despite the large distance from the wavemaker to the plate and the small amplitude of the incident wave, no steady state is attained by the end of the exploitable part of the records....

  19. Hepatic differentiation of human pluripotent stem cells in miniaturized format suitable for high-throughput screen

    Directory of Open Access Journals (Sweden)

    Arnaud Carpentier

    2016-05-01

    Full Text Available The establishment of protocols to differentiate human pluripotent stem cells (hPSCs including embryonic (ESC and induced pluripotent (iPSC stem cells into functional hepatocyte-like cells (HLCs creates new opportunities to study liver metabolism, genetic diseases and infection of hepatotropic viruses (hepatitis B and C viruses in the context of specific genetic background. While supporting efficient differentiation to HLCs, the published protocols are limited in terms of differentiation into fully mature hepatocytes and in a smaller-well format. This limitation handicaps the application of these cells to high-throughput assays. Here we describe a protocol allowing efficient and consistent hepatic differentiation of hPSCs in 384-well plates into functional hepatocyte-like cells, which remain differentiated for more than 3 weeks. This protocol affords the unique opportunity to miniaturize the hPSC-based differentiation technology and facilitates screening for molecules in modulating liver differentiation, metabolism, genetic network, and response to infection or other external stimuli.

  20. Static electromagnetic properties of giant resonances

    International Nuclear Information System (INIS)

    Koo, W.K.

    1986-03-01

    Static electric monopole and quadrupole matrix elements, which are related to the mean square radius and quadrupole moment respectively, are derived for giant resonances of arbitrary multipolarity. The results furnish information on the size and shape of the nucleus in the excited giant states. (author)

  1. Miniature magnetic fluid seal working in liquid environments

    Energy Technology Data Exchange (ETDEWEB)

    Mitamura, Yoshinori, E-mail: ymitamura@par.odn.ne.jp [Graduate School of Information Science and Technology, Hokkaido University, Sapporo 060-0814 (Japan); Durst, Christopher A., E-mail: chris@procyrion.com [Procyrion, Inc., Houston, TX 77027 (United States)

    2017-06-01

    This study was carried out to develop a miniature magnetic fluid (MF) seal working in a liquid environment. The miniature MF seal is intended for use in a catheter blood pump. The requirements for the MF seal included a size of less than Ø4×4.5 mm, shaft diameter of 1 mm, sealing pressure of 200 mmHg, shaft speed of up to 40000 rpm, and life of one month. The miniature MF seal was composed of an NdFeB magnet (Ø4×Ø2×1) sandwiched between two pole pieces (Ø4×Ø1.1×0.5). A shield (Ø4×Ø1.2×1.5) was placed on the pole piece facing the liquid to minimize the influence of pump flow on the MF. The seal was installed on a Ø1 shaft. A seal was formed by injecting MF (Ms: 47.8 kA/m and η: 0.5 Pa·sec) into the gap between the pole pieces and the shaft. Total volume of the MF seal was 44 μL. A sealing pressure of 370 mmHg was obtained at motor speeds of 0-40,000 rpm. The seal remained perfect for 10 days in saline under the condition of a pump flow of 1.5 L/min (The test was terminated in accordance with plans). The seal remained intact after ethylene oxide sterilization during which the seal was exposed to high pressures. In conclusion, the newly developed MF seal will be useful for a catheter pump. - Highlights: • A miniature magnetic fluid seal working in a liquid environment was developed. • The seal can be installed on Ø1 mm shaft and can seal against 370 mmHg at 40000 rpm. • The magnetic fluid seal will be useful for a catheter blood pump.

  2. Giant Radio Flare of Cygnus X-3 in September 2016

    Science.gov (United States)

    Trushkin, S. A.; Nizhelskij, N. A.; Tsybulev, P. G.; Zhekanis, G. V.

    2017-06-01

    In the long-term multi-frequency monitoring program of the microquasars with RATAN-600 we discovered the giant flare from X-ray binary Cyg X-3 on 13 September 2016. It happened after 2000 days of the 'quiescent state' of the source passed after the former giant flare (˜18 Jy) in March 2011. We have found that during this quiet period the hard X-ray flux (Swift/BAT, 15-50 keV) and radio flux (RATAN-600, 11 GHz) have been strongly anti-correlated. Both radio flares occurred after transitions of the microquasar to a 'hypersoft' X-ray state that occurred in February 2011 and in the end of August 2016. The giant flare was predicted by us in the first ATel (Trushkin et al. (2016)). Indeed after dramatic decrease of the hard X-ray Swift 15-50 keV flux and RATAN 4- 11 GHz fluxes (a 'quenched state') a small flare (0.7 Jy at 4-11 GHz) developed on MJD 57632 and then on MJD 57644.5 almost simultaneously with X-rays radio flux rose from 0.01 to 15 Jy at 4.6 GHz during few days. The rise of the flaring flux is well fitted by a exponential law that could be a initial phase of the relativistic electrons generation by internal shock waves in the jets. Initially spectra were optically thick at frequencies lower 2 GHz and optically thin at frequencies higher 8 GHz with typical spectral index about -0.5. After maximum of the flare radio fluxes at all frequencies faded out with exponential law.

  3. Nuclear fuel element end fitting

    International Nuclear Information System (INIS)

    Jabsen, F.S.

    1979-01-01

    A typical embodiment of the invention has an array of sockets that are welded to the intersections of the plates that form the upper and lower end fittings of a nuclear reactor fuel element. The sockets, which are generally cylindrical in shape, are oriented in directions that enable the longitudinal axes of the sockets to align with the longitudinal axes of the fuel rods that are received in the respective sockets. Detents impressed in the surfaces of the sockets engage mating grooves that are formed in the ends of the fuel rods to provide for the structural integrity of the fuel element

  4. Evolution in miniaturized column liquid chromatography instrumentation and applications: An overview.

    Science.gov (United States)

    Nazario, Carlos E D; Silva, Meire R; Franco, Maraíssa S; Lanças, Fernando M

    2015-11-20

    The purpose of this article is to underline the miniaturized LC instrumental system and describe the evolution of commercially available systems by discussing their advantages and drawbacks. Nowadays, there are already many miniaturized LC systems available with a great variety of pump design, interface and detectors as well as efficient columns technologies and reduced connections devices. The solvent delivery systems are able to drive the mobile phase without flow splitters and promote gradient elution using either dual piston reciprocating or syringe-type pumps. The mass spectrometry as detection system is the most widely used detection system; among many alternative ionization sources direct-EI LC-MS is a promising alternative to APCI. In addition, capillary columns are now available showing many possibilities of stationary phases, inner diameters and hardware materials. This review provides a discussion about miniaturized LC demonstrating fundamentals and instrumentals' aspects of the commercially available miniaturized LC instrumental system mainly nano and micro LC formats. This review also covers the recent developments and trends in instrumentation, capillary and nano columns, and several applications of this very important and promising field. Copyright © 2015 Elsevier B.V. All rights reserved.

  5. Bringing Low the Giants

    CERN Multimedia

    2001-01-01

    Their work goes on unseen, because they a hundred metres beneath your feet. But while the race against the clock to build the LHC has begun on the surface, teams underground are feverishly engaged to dismantle LEP and its experiments. Four months after the start of dismantling, the technical coordinators of the different experiments discuss the progress of work. Little men attack the giant ALEPH. The barrel and its two endcaps have been removed to the end of the cavern and stripped of their cables. The breaking up of the detector can now begin. At ALEPH, counting rooms removed all in one go Jean-Paul Fabre, technical coordinator at ALEPH:'After making safe the structure, the first step was to remove the wiring and cables. Some 210 cubic metres were brought out. Then the counting rooms all round the detector were taken out. They were brought up from the cavern all in one go, up through the shaft, which is 10 metres wide and 150 metres deep. They made it with 15 centimetres to spare. They have been emptied of...

  6. An Intraoral Miniature X-ray Tube Based on Carbon Nanotubes for Dental Radiography

    OpenAIRE

    Hyun Jin Kim; Hyun Nam Kim; Hamid Saeed Raza; Han Beom Park; Sung Oh Cho

    2016-01-01

    A miniature X-ray tube based on a carbon-nanotube electron emitter has been employed for the application to a dental radiography. The miniature X-ray tube has an outer diameter of 7 mm and a length of 47 mm. The miniature X-ray tube is operated in a negative high-voltage mode in which the X-ray target is electrically grounded. In addition, X-rays are generated only to the teeth directions using a collimator while X-rays generated to other directions are shielded. Hence, the X-ray tube can be ...

  7. Divertor plate for thermonuclear reactor

    International Nuclear Information System (INIS)

    Yamazaki, Seiichiro; Sato, Keisuke; Nishio, Satoshi.

    1993-01-01

    In a divertor plate for a thermonuclear reactor, adjacent cooling pipes are electrically insulated from each other and pipes made of a gradient functional material prepared by compositing ceramics having an insulation property and metals are metallurgically joined to at least one portion of each of the cooling pipes. Electric current caused upon occurrence of plasma disruption is interrupted by the insulation portion, so that a large circuit is not formed and electromagnetic force is decreased to such a extent that the divertor plate is not ruptured. Since a header of the cooling pipes can be installed at any optional position, the installation space can be reduced. Further, since inlet and exit collection headers can be disposed on both ends of the cooling pipes, it is possible to shorten the length of the cooling pipe of the divertor plate corresponded to high heat fluxes and reduce the pressure loss on the side of coolants to about 1/2. Further, turn back portions of small radius of curvature of the cooling pipes are eliminated to reduce the cost and extend the lifetime and, in addition, protection tiles can be attached easily. (N.H.)

  8. Design of the Flow Plates for a Dual Cooled Fuel Assembly

    International Nuclear Information System (INIS)

    Kim, Jae Yong; Yoon, Kyung Ho; Lee, Young Ho; Lee, Kang Hee; Kim, Hyung Kyu

    2009-01-01

    In a dual cooled fuel assembly, the array and position of fuels are changed from those of a conventional PWR fuel assembly to achieve a power uprating. The flow plate provides flow holes to direct the heated coolant into/out of the fuel assembly and structural intensity to insure that the fuel rod is axially restrained within the spacer grids. So, flow plates of top/bottom end pieces (TEP/BEP) have to be modified into proper shape. Because the flow holes' area of a flow plate affects pressure drop, the flow holes' area must be larger than/equal to that of conventional flow plates. And design criterion of the TEP/BEP says that the flow plate should withstand a 22.241 kN axial load during handling lest a calculated stress intensity should exceed the Condition I allowable stress. In this paper, newly designed flow plates of a TEP/BEP are suggested and stress analysis is conducted to evaluate strength robustness of the flow plates for the dual cooled fuel assembly

  9. Back pain's association with vertebral end-plate signal changes in sciatica.

    Science.gov (United States)

    el Barzouhi, Abdelilah; Vleggeert-Lankamp, Carmen L A M; van der Kallen, Bas F; Lycklama à Nijeholt, Geert J; van den Hout, Wilbert B; Koes, Bart W; Peul, Wilco C

    2014-02-01

    Patients with sciatica frequently experience disabling back pain. One of the proposed causes for back pain is vertebral end-plate signal changes (VESC) as visualized by magnetic resonance imaging (MRI). To report on VESC findings, changes of VESC findings over time, and the correlation between VESC and disabling back pain in patients with sciatica. A randomized clinical trial with 1 year of follow-up. Patients with 6 to 12 weeks of sciatica who participated in a multicenter, randomized clinical trial comparing an early surgery strategy with prolonged conservative care with surgery if needed. Patients were assessed by means of the 100-mm visual analog scale (VAS) for back pain (with 0 representing no pain and 100 the worst pain ever experienced) at baseline and 1 year. Disabling back pain was defined as a VAS score of at least 40 mm. Patients underwent MRI both at baseline and after 1 year follow-up. Presence and change of VESC was correlated with disabling back pain using chi-square tests and logistic regression analysis. At baseline, 39% of patients had disabling back pain. Of the patients with VESC at baseline, 40% had disabling back pain compared with 38% of the patients with no VESC (p=.67). The prevalence of type 1 VESC increased from 1% at baseline to 35% 1 year later in the surgical group compared with an increase from 3% to 11% in the conservative group. The prevalence of type 2 VESC decreased from 40% to 29% in the surgical group while remaining almost stable in the conservative group at 41%. The prevalence of disabling back pain at 1 year was 12% in patients with no VESC at 1 year, 16% in patients with type 1 VESC, 11% in patients with type 2 VESC, and 3% in patients with both types 1 and 2 VESC (p=.36). Undergoing surgery was associated with increase in the extent of VESC (odds ratio [OR], 8.6; 95% confidence interval [CI], 4.7-15.7; psciatica was highly associated with the development of VESC after 1 year. However, in contrast with the intuitive feeling

  10. Wearable devices for blood purification: principles, miniaturization, and technical challenges.

    Science.gov (United States)

    Armignacco, Paolo; Lorenzin, Anna; Neri, Mauro; Nalesso, Federico; Garzotto, Francesco; Ronco, Claudio

    2015-01-01

    The prevalences of end-stage renal disease (ESRD) and renal replacement therapy (RRT) continue to increase across the world imposing staggering costs on providers. Therefore, strategies to optimize the treatment and improve survival are of fundamental importance. Despite the benefits of daily dialysis, its implementation is difficult and wearable hemodialysis might represent an alternative by which frequent treatments can be delivered to ESRD patients with much less interference in their routines promoting better quality of life. The development of the wearable artificial kidney (WAK) requires incorporation of basic components of a dialysis system into a wearable device that allows mobility, miniaturization, and above all, patient-oriented management. The technical requirements necessary for WAK can be divided into the following broad categories: dialysis membranes, dialysis regeneration, vascular access, patient monitoring systems, and power sources. Pumping systems for blood and other fluids are the most critical components of the entire device. © 2015 Wiley Periodicals, Inc.

  11. Miniature fiber Bragg grating sensor interrogator (FBG-Transceiver) system

    Science.gov (United States)

    Mendoza, Edgar A.; Kempen, Cornelia; Lopatin, Craig

    2007-04-01

    This paper describes recent progress conducted towards the development of a miniature fiber Bragg grating sensor interrogator (FBG-Transceiver TM) system based on multi-channel integrated optic sensor (InOSense TM) microchip technology. The hybrid InOSense TM microchip technology enables the integration of all of the functionalities, both passive and active, of conventional bench top FBG sensor interrogator systems, packaged in a miniaturized, low power operation, 2-cm x 5-cm package suitable for the long-term structural health monitoring in applications where size, weight, and power are critical for operation. The FBG-Transceiver system uses active optoelectronic components monolithically integrated to the InOSense TM microchip, a microprocessor controlled signal processing electronics board capable of processing the FBG sensors signals related to stress-strain and temperature as well as vibration and acoustics. The FBG-Transceiver TM system represents a new, reliable, highly robust technology that can be used to accurately monitor the status of an array of distributed fiber optic Bragg grating sensors installed in critical infrastructures. Its miniature package, low power operation, and state-of-the-art data communications architecture, all at a very affordable price makes it a very attractive solution for a large number of SHM/NDI applications in aerospace, naval and maritime industry, civil structures like bridges, buildings and dams, the oil and chemical industry, and for homeland security applications. The miniature, cost-efficient FBG-Transceiver TM system is poised to revolutionize the field of structural health monitoring and nondestructive inspection market. The sponsor of this program is NAVAIR under a DOD SBIR contract.

  12. MIT miniaturized disk bend test

    International Nuclear Information System (INIS)

    Harling, O.K.; Lee, M.; Sohn, D.S.; Kohse, G.; Lau, C.W.

    1983-01-01

    A miniaturized disk bend test (MDBT) using transmission electron microscopy specimens for the determination of various mechanical properties is being developed at MIT. Recent progress in obtaining strengths and ductilities of highly irradiated metal alloys is reviewed. Other mechanical properties can also be obtained using the MDBT approach. Progress in fatigue testing and in determination of the ductile-to-brittle transition temperature is reviewed briefly. 11 figures

  13. High prevalence of the c.74A>C SPINK1 variant in miniature and standard Schnauzers.

    Science.gov (United States)

    Furrow, E; Armstrong, P J; Patterson, E E

    2012-01-01

    Variants in the serine protease inhibitor Kazal type 1 (SPINK1) gene have been associated with pancreatitis in Miniature Schnauzers. Replication of the association in an independent population is necessary to determine if genetic screening for SPINK1 variants should be considered in clinical practice. An association between the SPINK1 exonic variant c.74A > C and pancreatitis exists in Miniature Schnauzers. In addition, the variant is absent or rare in Standard Schnauzers, a related breed that is not reported to have an increased risk for pancreatitis. Case-control study. Seventeen Miniature Schnauzers with pancreatitis (cases), 60 mature Miniature Schnauzers with no substantial history of gastrointestinal signs in their lifetime (controls), and 31 Standard Schnauzers of unknown pancreatitis status. A PCR-RFLP assay was used to genotype dogs for the c.74A > C SPINK1 variant. Allele and genotype frequencies were reported for Schnauzers and compared between case and control Miniature Schnauzers. The c.74A > C variant was the major allele in both Schnauzer breeds with a frequency of 0.77 in Miniatures and 0.55 in Standards. The allele and genotype frequencies were similar between Miniature Schnauzers with and without a history of pancreatitis and did not impart an increased risk for pancreatitis. Genotyping a larger population of the Miniature Schnauzer breed than a previous study, along with a Standard Schnauzer cohort, demonstrated that the SPINK1 c.74A > C variant is a common polymorphism in the Schnauzer lineage. Furthermore, we were unable to confirm a relationship between the variant and clinically detectable pancreatitis in Miniature Schnauzers. Copyright © 2012 by the American College of Veterinary Internal Medicine.

  14. Miniature piezo electric vacuum inlet valve

    Science.gov (United States)

    Keville, Robert F.; Dietrich, Daniel D.

    1998-03-24

    A miniature piezo electric vacuum inlet valve having a fast pulse rate and is battery operated with variable flow capability. The low power (piezo electric valves which require preloading of the crystal drive mechanism and 120 Vac, thus the valve of the present invention is smaller by a factor of three.

  15. A Miniaturized Variable Pressure Scanning Electron Microscope (MVP-SEM) for the Surface of Mars: An Instrument for the Planetary Science Community

    Science.gov (United States)

    Edmunson, J.; Gaskin, J. A.; Danilatos, G.; Doloboff, I. J.; Effinger, M. R.; Harvey, R. P.; Jerman, G. A.; Klein-Schoder, R.; Mackie, W.; Magera, B.; hide

    2016-01-01

    The Miniaturized Variable Pressure Scanning Electron Microscope(MVP-SEM) project, funded by the NASA Planetary Instrument Concepts for the Advancement of Solar System Observations (PICASSO) Research Opportunities in Space and Earth Science (ROSES), will build upon previous miniaturized SEM designs for lunar and International Space Station (ISS) applications and recent advancements in variable pressure SEM's to design and build a SEM to complete analyses of samples on the surface of Mars using the atmosphere as an imaging medium. By the end of the PICASSO work, a prototype of the primary proof-of-concept components (i.e., the electron gun, focusing optics and scanning system)will be assembled and preliminary testing in a Mars analog chamber at the Jet Propulsion Laboratory will be completed to partially fulfill Technology Readiness Level to 5 requirements for those components. The team plans to have Secondary Electron Imaging(SEI), Backscattered Electron (BSE) detection, and Energy Dispersive Spectroscopy (EDS) capabilities through the MVP-SEM.

  16. Hydrodynamics of a flexible plate between pitching rigid plates

    Science.gov (United States)

    Kim, Junyoung; Kim, Daegyoum

    2017-11-01

    The dynamics of a flexible plate have been studied as a model problem in swimming and flying of animals and fluid-structure interaction of plants and flags. Motivated by fish schooling and an array of sea grasses, we investigate the dynamics of a flexible plate closely placed between two pitching rigid plates. In most studies on passive deformation of the flexible plate, the plate is immersed in a uniform flow or a wavy flow. However, in this study, the flexible plate experiences periodic deformation by the oscillatory flow generated by the prescribed pitching motion of the rigid plates. In our model, the pitching axes of the rigid plates and the clamping position of the flexible plate are aligned on the same line. The flexible plate shows various responses depending on length and pitching frequency of rigid plates, thickness of a flexible plate, and free-stream velocity. To find the effect of each variable on the response of the flexible plate, amplitude of a trailing edge and modal contribution of a flapping motion are compared, and flow structure around the flexible plate is examined.

  17. Miniature fiber-optic multiphoton microscopy system using frequency-doubled femtosecond Er-doped fiber laser.

    Science.gov (United States)

    Huang, Lin; Mills, Arthur K; Zhao, Yuan; Jones, David J; Tang, Shuo

    2016-05-01

    We report on a miniature fiber-optic multiphoton microscopy (MPM) system based on a frequency-doubled femtosecond Er-doped fiber laser. The femtosecond pulses from the laser source are delivered to the miniature fiber-optic probe at 1.58 µm wavelength, where a standard single mode fiber is used for delivery without the need of free-space dispersion compensation components. The beam is frequency-doubled inside the probe by a periodically poled MgO:LiNbO3 crystal. Frequency-doubled pulses at 786 nm with a maximum power of 80 mW and a pulsewidth of 150 fs are obtained and applied to excite intrinsic signals from tissues. A MEMS scanner, a miniature objective, and a multimode collection fiber are further used to make the probe compact. The miniature fiber-optic MPM system is highly portable and robust. Ex vivo multiphoton imaging of mammalian skins demonstrates the capability of the system in imaging biological tissues. The results show that the miniature fiber-optic MPM system using frequency-doubled femtosecond fiber laser can potentially bring the MPM imaging for clinical applications.

  18. Burn up calculations for the Iranian miniature reactor: A reliable and safe research reactor

    International Nuclear Information System (INIS)

    Faghihi, F.; Mirvakili, S.M.

    2009-01-01

    Presenting neutronic calculations pertaining to the Iranian miniature research reactor is the main goal of this article. This is a key to maintaining safe and reliable core operation. The following reactor core neutronic parameters were calculated: clean cold core excess reactivity (ρ ex ), control rod and shim worth, shut down margin (SDM), neutron flux distribution of the reactor core components, and reactivity feedback coefficients. Calculations for the fuel burnup and radionuclide inventory of the Iranian miniature neutron source reactor (MNSR), after 13 years of operational time, are carried out. Moreover, the amount of uranium burnup and produced plutonium, the concentrations and activities of the most important fission products, the actinide radionuclides accumulated, and the total radioactivity of the core are estimated. Flux distribution for both water and fuel temperature increases are calculated and changes of the central control rod position are investigated as well. Standard neutronic simulation codes WIMS-D4 and CITATION are employed for these studies. The input model was validated by the experimental data according to the final safety analysis report (FSAR) of the reactor. The total activity of the MNSR core is calculated including all radionuclides at the end of the core life and it is found to be equal to 1.3 x 10 3 Ci. Our investigation shows that the reactor is operating under safe and reliable conditions.

  19. Burn up calculations for the Iranian miniature reactor: A reliable and safe research reactor

    Energy Technology Data Exchange (ETDEWEB)

    Faghihi, F. [Department of Nuclear Engineering, School of Engineering, Shiraz University, Shiraz 71345 (Iran, Islamic Republic of); Research Center for Radiation Protection, Shiraz University, Shiraz (Iran, Islamic Republic of)], E-mail: faghihif@shirazu.ac.ir; Mirvakili, S.M. [Department of Nuclear Engineering, School of Engineering, Shiraz University, Shiraz 71345 (Iran, Islamic Republic of)

    2009-06-15

    Presenting neutronic calculations pertaining to the Iranian miniature research reactor is the main goal of this article. This is a key to maintaining safe and reliable core operation. The following reactor core neutronic parameters were calculated: clean cold core excess reactivity ({rho}{sub ex}), control rod and shim worth, shut down margin (SDM), neutron flux distribution of the reactor core components, and reactivity feedback coefficients. Calculations for the fuel burnup and radionuclide inventory of the Iranian miniature neutron source reactor (MNSR), after 13 years of operational time, are carried out. Moreover, the amount of uranium burnup and produced plutonium, the concentrations and activities of the most important fission products, the actinide radionuclides accumulated, and the total radioactivity of the core are estimated. Flux distribution for both water and fuel temperature increases are calculated and changes of the central control rod position are investigated as well. Standard neutronic simulation codes WIMS-D4 and CITATION are employed for these studies. The input model was validated by the experimental data according to the final safety analysis report (FSAR) of the reactor. The total activity of the MNSR core is calculated including all radionuclides at the end of the core life and it is found to be equal to 1.3 x 10{sup 3}Ci. Our investigation shows that the reactor is operating under safe and reliable conditions.

  20. Miniaturized star tracker for micro spacecraft with high angular rate

    Science.gov (United States)

    Li, Jianhua; Li, Zhifeng; Niu, Zhenhong; Liu, Jiaqi

    2017-10-01

    There is a clear need for miniaturized, lightweight, accurate and inexpensive star tracker for spacecraft with large anglar rate. To face these new constraints, the Beijing Institute of Space Long March Vehicle has designed, built and flown a low cost miniaturized star tracker that provides autonomous ("Lost in Space") inertial attitude determination, 2 Hz 3-axis star tracking, and digital imaging with embedded compression. Detector with high sensitivity is adopted to meet the dynamic and miniature requirement. A Sun and Moon avoiding method based on the calculation of Sun and Moon's vector by astronomical theory is proposed. The produced prototype weight 0.84kg, and can be used for a spacecraft with 6°/s anglar rate. The average angle measure error is less than 43 arc second. The ground verification and application of the star tracker during the pick-up flight test showed that the capability of the product meet the requirement.

  1. Giant Urinary Bladder and Bilateral Giant Hydronephrosis due to Bladder Neck Obstruction: One Case Report and Literature Review

    Directory of Open Access Journals (Sweden)

    Mohammed Fadl Tazi

    2012-01-01

    Full Text Available Bilateral hydronephrosis secondary to urinary obstruction leads to a buildup of back pressure in the urinary tract and may lead to impairment of renal function. Cases of giant hydronephrosis are rare and usually contain no more than 1-2 litres of fluid in the collecting system. Here, we report a rarely seen case with giant urinary bladder and bilateral giant hydronephrosis due to bladder neck obstruction which contains 4000 mL fluid in the collecting system of the kidney mimicking an ascites in an adult male.

  2. Use of urinary 13,14, dihydro-15-keto-prostaglandin F2α (PGFM concentrations to diagnose pregnancy and predict parturition in the giant panda (Ailuropoda melanolecua.

    Directory of Open Access Journals (Sweden)

    Beth M Roberts

    Full Text Available Pregnancy determination is difficult in the giant panda (Ailuropoda melanolecua, representing a challenge for ex situ conservation efforts. Research in other species experiencing pseudopregnancy indicates that urinary/fecal concentrations of 13,14, dihydro-15-keto-prostaglandin F2α (PGFM can accurately determine pregnancy status. Our objective was to determine if urinary PGFM concentrations are associated with pregnancy status in the giant panda. Urinary PGFM concentrations were measured in female giant pandas (n = 4 throughout gestation (n = 6 and pseudopregnancy (n = 4 using a commercial enzyme immunoassay. Regardless of pregnancy status, PGFM excretion followed a predictable pattern: 1 baseline concentrations for 11-19 weeks following ovulation; 2 a modest, initial peak 14-36 days after the start of the secondary urinary progestagen rise; 3 a subsequent period of relatively low concentrations; and 4 a large, terminal peak at the end of the luteal phase. Pregnant profiles were distinguished by an earlier initial peak (P = 0.024, higher inter-peak concentrations (P < 0.001, and a larger terminal peak (P = 0.003 compared to pseudopregnancy profiles. Parturition occurred 23 to 25 days from the initial PGFM surge and within 24 hours of the start of the terminal increase. These pattern differences indicate that urinary PGFM monitoring can be used to predict pregnancy status and time parturition in the giant panda. Furthermore, this is the only species known to exhibit a significant PGFM increase during pseudopregnancy, suggesting a unique physiological mechanism for regulating the end of the luteal phase in the giant panda.

  3. Giant cell arteritis of fallopian tube.

    Science.gov (United States)

    Azzena, A; Altavilla, G; Salmaso, R; Vasoin, F; Pellizzari, P; Doria, A

    1994-01-01

    One case of giant cells arteritis involving tubaric arteries in a postmenopausal woman is described. The patient was 59 years old and presented with asthenia, anemia, fever, weight loss, an abdominal palpable mass and elevated erythrocyte sedimentation rate. Exploratory laparotomy revealed a large ovarian cyst of 14 cm in diameter. Extensive giant cell arteritis, Horton's type, of the small-sizes arteries was found unexpectedly in the fallopian tube of the patient who had had a prior ovariectomy. Giant cell arteritis of the female genital tract is a rare finding in elderly women and may occur as an isolated finding or as part of generalised arteritis.

  4. Plans for miniature machining at LASL

    International Nuclear Information System (INIS)

    Rhorer, R.L.

    1979-01-01

    A special shop for making miniature or very small parts is being established within the LASL Shop Department, and one of the machine tools for this shop is a high precision lathe. The report describes a method based on scale modeling analysis which was used to define the specific requirements for this lathe

  5. Fabrication of a Miniaturized ZnO Nanowire Accelerometer and Its Performance Tests

    Directory of Open Access Journals (Sweden)

    Hyun Chan Kim

    2016-09-01

    Full Text Available This paper reports a miniaturized piezoelectric accelerometer suitable for a small haptic actuator array. The accelerometer is made with zinc oxide (ZnO nanowire (NW grown on a copper wafer by a hydrothermal process. The size of the accelerometer is 1.5 × 1.5 mm2, thus fitting the 1.8 × 1.8 mm2 haptic actuator array cell. The detailed fabrication process of the miniaturized accelerometer is illustrated. Performance evaluation of the fabricated accelerometer is conducted by comparing it with a commercial piezoelectric accelerometer. The output current of the fabricated accelerometer increases linearly with the acceleration. The miniaturized ZnO NW accelerometer is feasible for acceleration measurement of small and lightweight devices.

  6. Miniaturized Airborne Imaging Central Server System, Phase I

    Data.gov (United States)

    National Aeronautics and Space Administration — The innovation is a miniaturized airborne imaging central server system (MAICSS). MAICSS is designed as a high-performance-computer-based electronic backend that...

  7. Miniaturized Airborne Imaging Central Server System, Phase II

    Data.gov (United States)

    National Aeronautics and Space Administration — The innovation is a miniaturized airborne imaging central server system (MAICSS). MAICSS is designed as a high-performance computer-based electronic backend that...

  8. Miniaturized optical sensors based on lens arrays

    DEFF Research Database (Denmark)

    Hanson, Steen Grüner; Jakobsen, M.L.; Larsen, H.E.

    2005-01-01

    A suite of optical sensors based on the use of lenticular arrays for probing mechanical deflections will be displayed. The optical systems are well suited for miniaturization, and utilize speckles as the information-carriers. This implementation allows for acquiring directional information...

  9. Staged Closure of Giant Omphalocele using Synthetic Mesh

    OpenAIRE

    Parida, Lalit; Pal, Kamalesh; Al Buainain, Hussah; Elshafei, Hossam

    2014-01-01

    Giant omphalocele is difficult to manage and is associated with a poor outcome. A male newborn presented to our hospital with a giant omphalocele. We performed a staged closure of giant omphalocele using synthetic mesh to construct a silo and then mesh abdominoplasty in the neonatal period that led to a successful outcome within a reasonable period of hospital stay.

  10. Giant microelectronics

    International Nuclear Information System (INIS)

    Della Sala, D.; Privato, C.; Di Lazzaro, P.; Fortunato, G.

    1999-01-01

    Giant microelectronics, on which the technology of flat liquid-crystal screens is based, is an example of fruitful interaction among independently-developed technologies, in this case thin film micro devices and laser applications. It typifies the interdisciplinary approach needed to produce innovations in microelectronics [it

  11. Miniaturized Environmental Scanning Electron Microscope for In Situ Planetary Studies

    Science.gov (United States)

    Gaskin, Jessica; Abbott, Terry; Medley, Stephanie; Gregory, Don; Thaisen, Kevin; Taylor , Lawrence; Ramsey, Brian; Jerman, Gregory; Sampson, Allen; Harvey, Ralph

    2010-01-01

    The exploration of remote planetary surfaces calls for the advancement of low power, highly-miniaturized instrumentation. Instruments of this nature that are capable of multiple types of analyses will prove to be particularly useful as we prepare for human return to the moon, and as we continue to explore increasingly remote locations in our Solar System. To this end, our group has been developing a miniaturized Environmental-Scanning Electron Microscope (mESEM) capable of remote investigations of mineralogical samples through in-situ topographical and chemical analysis on a fine scale. The functioning of an SEM is well known: an electron beam is focused to nanometer-scale onto a given sample where resulting emissions such as backscattered and secondary electrons, X-rays, and visible light are registered. Raster scanning the primary electron beam across the sample then gives a fine-scale image of the surface topography (texture), crystalline structure and orientation, with accompanying elemental composition. The flexibility in the types of measurements the mESEM is capable of, makes it ideally suited for a variety of applications. The mESEM is appropriate for use on multiple planetary surfaces, and for a variety of mission goals (from science to non-destructive analysis to ISRU). We will identify potential applications and range of potential uses related to planetary exploration. Over the past few of years we have initiated fabrication and testing of a proof-of-concept assembly, consisting of a cold-field-emission electron gun and custom high-voltage power supply, electrostatic electron-beam focusing column, and scanning-imaging electronics plus backscatter detector. Current project status will be discussed. This effort is funded through the NASA Research Opportunities in Space and Earth Sciences - Planetary Instrument Definition and Development Program.

  12. Miniature Inertial and Augmentation Sensors for Integrated Inertial/GPS Based Navigation Applications

    Science.gov (United States)

    2010-03-01

    Magnetometer (Ref [23]) Until miniature atomic magnetometers transition from laboratory demonstration units to a mass produced product, fluxgate ...and/or magnetoresistive designs are a better suited magnetometer technology for a miniature navigation system. Figure 8 below shows the basic fluxgate ...is required to resolve magnetic field orientation. Fig 8. Fluxgate Magnetometer Schematic The PNI Sensor Corporation (Santa Rosa, CA

  13. Novel Miniature Spectrometer For Remote Chemical Detection

    International Nuclear Information System (INIS)

    Pipino, Andrew C.R.

    2000-01-01

    New chemical sensing technologies are critically important for addressing many of EM's priority needs as discussed in detail at http://emsp.em.doe.gov/needs. Many technology needs were addressed by this research. For example, improved detection strategies are needed for non-aqueous phase liquids (NAPL's), such as PCE (Cl2C=CCl2) and TCE (HClC=CCl2), which persist in the environment due their highly stable structures. By developing a miniature, ultra-sensitive, selective, and field-deployable detector for NAPL's, the approximate source location could be determined with minimal investigative expense. Contaminant plumes could also be characterized in detail. The miniature spectrometer developed under Project No.60231 could also permit accurate rate measurements in less time, either in the field or the laboratory, which are critically important in the development, testing, and ultimate utilization of models for describing contaminant transport. The technology could also be used for long-term groundwater monitoring or long-term stewardship in general. Many science needs are also addressed by the Project 60231, since the effort significantly advances the measurement science of chemical detection. Developed under Project No.60231, evanescent wave cavity ring-down spectroscopy (EW-CRDS) is a novel form of CRDS, which is an the emerging optical absorption technique. Several review articles on CRDS, which has been generally applied only to gas-phase diagnostics, have been published1-3. EW-CRDS4-10 forms the basis for a new class of chemical sensors that extends CRDS to other states of matter and leads to a miniaturized version of the concept. EW-CRDS uses miniature solid-state optical resonators that incorporate one or more total internal reflection (TIR) surfaces, which create evanescent waves. The evanescent waves emanate from the TIR surfaces, sampling the surrounding medium. The utility of evanescent waves in chemical analysis forms the basis for the field of attenuated

  14. Weighted anisotropic Korn's inequality for a junction of a plate and a rod

    International Nuclear Information System (INIS)

    Nazarov, S A

    2004-01-01

    Korn's inequality is proved for an elastic body obtained by attaching to a plate several rods with clamped farther ends. The thickness of the plate and the diameters of the rods are characterized by a single small parameter h, which also gauges the distinctions in the elastic properties of the elements of the junction. The selection of the weighted anisotropic norms distinguishing the longitudinal and transverse directions in the plate and in a rod ensures the asymptotic accuracy of the inequality, which is substantiated by examples of particular constructions. New results on single plates and rods are obtained in the course of the proof.

  15. Giant prolactinomas in women

    DEFF Research Database (Denmark)

    Delgrange, Etienne; Raverot, Gerald; Bex, Marie

    2014-01-01

    OBJECTIVE: To characterise distinctive clinical features of giant prolactinomas in women. DESIGN: A multicentre, retrospective case series and literature review. METHODS: We collected data from 15 female patients with a pituitary tumour larger than 4 cm and prolactin levels above 1000 μg/l and id......OBJECTIVE: To characterise distinctive clinical features of giant prolactinomas in women. DESIGN: A multicentre, retrospective case series and literature review. METHODS: We collected data from 15 female patients with a pituitary tumour larger than 4 cm and prolactin levels above 1000 μg....../l and identified 19 similar cases from the literature; a gender-based comparison of the frequency and age distribution was obtained from a literature review. RESULTS: The initial PubMed search using the term 'giant prolactinomas' identified 125 patients (13 women) responding to the inclusion criteria. The female......:male ratio was 1:9. Another six female patients were found by extending the literature search, while our own series added 15 patients. The median age at diagnosis was 44 years in women compared with 35 years in men (Pwomen (n=34), we...

  16. Inherited retinal dysplasia and persistent hyperplastic primary vitreous in Miniature Schnauzer dogs.

    Science.gov (United States)

    Grahn, Bruce H; Storey, Eric S; McMillan, Catherine

    2004-01-01

    The objectives of this study were to define the clinical syndrome of retinal dysplasia and persistent primary vitreous in Miniature Schnauzer dogs and determine the etiology. We examined 106 Miniature Schnauzers using a biomicroscope and indirect ophthalmoscope. The anterior and posterior segments of affected dogs were photographed. Four enucleated eyes were examined using routine light microscopy and scanning electron microscopy. A pedigree was constructed and related dogs were test-bred to define the mode of inheritance of this syndrome. Congenital retinal dysplasia was confirmed in 24 of 106 related Miniature Schnauzer dogs. Physical and postmortem examinations revealed that congenital abnormalities were limited to the eyes. Biomicroscopic, indirect ophthalmoscopic, and neuro-ophthalmic examinations confirmed that some of these dogs were blind secondary to bilateral retinal dysplasia and detachment (nonattachment) (n = 13), and the remainder had generalized retinal dysplasia (n = 11). Fifteen of these dogs were also diagnosed with unilateral (n = 9) or bilateral (n = 6) persistent hyperplastic primary vitreous. Nutritional, infectious, or toxic etiologies were not evident on physical, postmortem, light microscopic, or transmitting and scanning electron microscopic examination of four affected Miniature Schnauzers. We examined the pedigree and determined that an autosomal recessive mode of inheritance was most likely. Three test-bred litters including those from affected parents, carrier and affected parents, and carrier parents confirmed this mode of inheritance. This study confirms that retinal dysplasia and persistent hyperplastic primary vitreous is a congenital abnormality that is inherited as an autosomal recessive condition in Miniature Schnauzers.

  17. Observing giant panda habitat and forage abundance from space

    NARCIS (Netherlands)

    Wang, T.

    2009-01-01

    Giant pandas are obligate bamboo grazers. The bamboos favoured by giant
    pandas are typical forest understorey plants. Therefore, the availability and
    abundance of understorey bamboo is a key factor in determining the quantity
    and quality of giant panda food resources. However,

  18. Metastatic giant basal cell carcinoma: a case report.

    Science.gov (United States)

    Bellahammou, Khadija; Lakhdissi, Asmaa; Akkar, Othman; Rais, Fadoua; Naoual, Benhmidou; Elghissassi, Ibrahim; M'rabti, Hind; Errihani, Hassan

    2016-01-01

    Basal cell carcinoma is the most common skin cancer, characterised by a slow growing behavior, metastasis are extremely rare, and it occurs in less than 0, 1% of all cases. Giant basal cell carcinoma is a rare form of basal cell carcinoma, more aggressive and defined as a tumor measuring more than 5 cm at its largest diameter. Only 1% of all basal cell carcinoma develops to a giant basal cell carcinoma, resulting of patient's negligence. Giant basal cell carcinoma is associated with higher potential of metastasis and even death, compared to ordinary basal cell carcinoma. We report a case of giant basal cell carcinoma metastaticin lung occurring in a 79 years old male patient, with a fatal evolution after one course of systemic chemotherapy. Giant basal cell carcinoma is a very rare entity, early detection of these tumors could prevent metastasis occurrence and improve the prognosis of this malignancy.

  19. 3D lumped components and miniaturized bandpass filter in an ultra-thin M-LCP for SOP applications

    KAUST Repository

    Arabi, Eyad A.

    2013-01-01

    In this work, a library of 3D lumped components completely embedded in the thinnest, multilayer LCP (M-LCP) stack- up with four metallization layers and 100 μm of total thickness, is reported for the first time. A vertically and horizontally interdigitated capacitor, realized in this stack-up, provides higher self resonant frequency as compared to a similarly sized conventional parallel plate capacitor. Based on the above mentioned library, a miniaturized bandpass filter is presented for the GPS application. It utilizes mutually coupled inductors and is the smallest reported in the literature with a size of (0.035×0.028×0.00089)λg. Finally, the same filter realized in a competing ceramic technology (LTCC) is compared in performance with the ultra-thin M-LCP design. The M-LCP module presented in this work is inherently exible and offers great potential for wearable and conformal applications.

  20. An Intraoral Miniature X-ray Tube Based on Carbon Nanotubes for Dental Radiography

    Directory of Open Access Journals (Sweden)

    Hyun Jin Kim

    2016-06-01

    Full Text Available A miniature X-ray tube based on a carbon-nanotube electron emitter has been employed for the application to a dental radiography. The miniature X-ray tube has an outer diameter of 7 mm and a length of 47 mm. The miniature X-ray tube is operated in a negative high-voltage mode in which the X-ray target is electrically grounded. In addition, X-rays are generated only to the teeth directions using a collimator while X-rays generated to other directions are shielded. Hence, the X-ray tube can be safely inserted into a human mouth. Using the intra-oral X-ray tube, a dental radiography is demonstrated where the positions of an X-ray source and a sensor are reversed compared with a conventional dental radiography system. X-ray images of five neighboring teeth are obtained and, furthermore, both left and right molar images are achieved by a single X-ray shot of the miniature X-ray tube.

  1. An intraoral miniature x-ray tube based on carbon nanotubes for dental radiography

    International Nuclear Information System (INIS)

    Kim, Hyun Jin; Kim, Hyun Nam; Raza, Hamid Saeed; Park, Han Beom; Cho, Sung Oh

    2016-01-01

    A miniature X-ray tube based on a carbon-nanotube electron emitter has been employed for the application to a dental radiography. The miniature X-ray tube has an outer diameter of 7 mm and a length of 47 mm. The miniature X-ray tube is operated in a negative high-voltage mode in which the X-ray target is electrically grounded. In addition, X-rays are generated only to the teeth directions using a collimator while X-rays generated to other directions are shielded. Hence, the X-ray tube can be safely inserted into a human mouth. Using the intra-oral X-ray tube, a dental radiography is demonstrated where the positions of an X-ray source and a sensor are reversed compared with a conventional dental radiography system. X-ray images of five neighboring teeth are obtained and, furthermore, both left and right molar images are achieved by a single X-ray shot of the miniature X-ray tube

  2. An intraoral miniature x-ray tube based on carbon nanotubes for dental radiography

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Hyun Jin; Kim, Hyun Nam; Raza, Hamid Saeed; Park, Han Beom; Cho, Sung Oh [Dept. of Nuclear and Quantum Engineering, Korea Advanced Institute of Science and Technology, Daejeon (Korea, Republic of)

    2016-06-15

    A miniature X-ray tube based on a carbon-nanotube electron emitter has been employed for the application to a dental radiography. The miniature X-ray tube has an outer diameter of 7 mm and a length of 47 mm. The miniature X-ray tube is operated in a negative high-voltage mode in which the X-ray target is electrically grounded. In addition, X-rays are generated only to the teeth directions using a collimator while X-rays generated to other directions are shielded. Hence, the X-ray tube can be safely inserted into a human mouth. Using the intra-oral X-ray tube, a dental radiography is demonstrated where the positions of an X-ray source and a sensor are reversed compared with a conventional dental radiography system. X-ray images of five neighboring teeth are obtained and, furthermore, both left and right molar images are achieved by a single X-ray shot of the miniature X-ray tube.

  3. Near-net shape manufacturing of miniature spur gears by wire spark erosion machining

    CERN Document Server

    Gupta, Kapil

    2016-01-01

    This work describes an experimental investigation with the aim to evaluate and establish wire spark erosion machining (WSEM) as a viable alternative for high quality miniature gear manufacturing. External spur type miniature brass (ASTM 858) gears with 12 teeth, 9.8 mm outside diameter and 5 mm face width were manufactured by WSEM. The research work was accomplished in four distinct experimental stages viz., preliminary, pilot, main and confirmation. The aim, scope and findings of each stage are progressively presented and discussed. In essence, the investigation found that it was possible to manufacture miniature gears to high quality by using WSEM. Gears up to DIN 5 quality with a good surface finish (1.2 µm average roughness) and satisfactory surface integrity were achieved. The results suggest that WSEM should be considered a viable alternative to conventional miniature gear manufacturing techniques and that in some instances it may even be superior. This work will prove useful to researchers and profess...

  4. Giant Chancroid

    Directory of Open Access Journals (Sweden)

    Bhushan Kumar

    1980-01-01

    Full Text Available A case of giant chancroid following rupture of inguinal bubo and having systemic symptoms is described. Response with sulfa and streptomycin combination was excellent and the lesion healed completely in 3 weeks. Early diagnosis and treatment of chancroid will prevent this debilitating complication.

  5. Giant cystic craniopharyngiomas

    International Nuclear Information System (INIS)

    Young, S.C.; Zimmerman, R.A.; Nowell, M.A.; Bilaniuk, L.T.; Hackney, D.B.; Grossman, R.I.; Goldberg, H.I.

    1987-01-01

    Three cases of giant cystic craniopharyngiomas with large areas of extension beyond the suprasellar area are presented. The magnetic resonance (MR) appearance in one case is described. These giant tumors had large, multilobulated cysts that comprised the bulk of the tumors. In one case, there was an unusual extension of the large tumor cyst into the lateral ventricle. In two cases, the tumors extended to the level of the foramen magnum. On CT, the cyst contents of these two tumors were hyperdense and became hypodense postoperatively. All three tumors harbored calcifications in the form of clumps in the suprasellar region and rim calcifications around the cysts. None of the tumors exhibited contrast enhancement. A literature review of the radiographic features of craniopharyngiomas is discussed. (orig.)

  6. Technologies for highly miniaturized autonomous sensor networks

    NARCIS (Netherlands)

    Baert, K.; Gyselinckx, B.; Torfs, T.; Leonov, V.; Yazicioglu, F.; Brebels, S.; Donnay, S.; Vanfleteren, J.; Beyne, E.; Hoof, C. van

    2006-01-01

    Recent results of the autonomous sensor research program HUMAN++ will be summarized in this paper. The research program aims to achieve highly miniaturized and (nearly) autonomous sensor systems that assist our health and comfort. Although the application examples are dedicated to human

  7. Miniaturized measurement system for ammonia in air

    NARCIS (Netherlands)

    Timmer, B.H.; van Delft, K.M.; Otjes, R.P.; Olthuis, Wouter; van den Berg, Albert

    2004-01-01

    The development of a miniaturized ammonia sensor made using microsystem technology is described. Gas is sampled in a sampler comprising two opposite channels separated by a gas permeable, water repellent polypropylene membrane. Subsequently, the acid sample solution is pumped into a selector where

  8. Biomechanical and biological aspects of defect treatment in fractures using helical plates.

    Science.gov (United States)

    Perren, S M; Regazzoni, P; Fernandez, A A D

    2014-01-01

    . Its application is fairly simple: The helical plate is modified conventional long and small plate that is twisted between its ends about 90 degrees. The twist is applied using "bending irons" (4, 5, 8) whereby the force required is small and the exact degree of twist is not critical. Therefore the twist is applicable operating bending irons by hand. Assuming a situation where a plate bridging a defect or non-union has failed the broken plate is replaced by a similar implant: At the distal end of the bone fracture and opposite to the surgical approach a small incision allows to slide in the helical plate in such a way that proximally the plate ends on the same side of the limb as the replaced plate. Ideally the two plate ends meet and the application of the helical plate does not ask for an additional surgical exposure at this location. Otherwise a small minimally invasive exposure is required. The helical plate is then fixed to the main bone fragments using a couple of locked screws. The following case demonstrates the use and efficiency of the helical plate saving a situation where multiple attempts using conventional plates had failed. The successful final treatment of this case was performed by A. A. D. Fernandez.

  9. CMS Hadronic EndCap Calorimeter Upgrade R&D Studies

    CERN Document Server

    Akgun, Ugur; Onel, Yasar

    2012-01-01

    Due to an expected increase in radiation damage in LHC, we propose to replace the active material of the CMS Hadronic EndCap calorimeters with radiation hard quartz plate. Quartz is proven to be radiation hard with radiation damage tests using electron, proton, neutron and gamma beams. However, the light produced in quartz is from Cerenkov process, which yields drastically fewer photons than scintillators. To increase the light collection efficiency we pursue two separate methods: First method: use wavelength shifting (WLS) fibers, which have been shown to collect efficiently the Cerenkov light generated in quartz plates. A quartz plate calorimeter prototype with WLS fibers has been constructed and tested at CERN that shows this method is feasible. Second proposed solution is to treat the quartz plates with radiation hard wavelength shifters, p-terphenyl, doped zinc oxide, or doped CdS. Another calorimeter prototype has been constructed with p-terphenyl deposited quartz plates, and showed superior calorimeter...

  10. Design and analysis of miniature tri-axial fluxgate magnetometer

    Science.gov (United States)

    Zhi, Menghui; Tang, Liang; Qiao, Donghai

    2017-02-01

    The detection technology of weak magnetic field is widely used in Earth resource survey and geomagnetic navigation. Useful magnetic field information can be obtained by processing and analyzing the measurement data from magnetic sensors. A miniature tri-axial fluxgate magnetometer is proposed in this paper. This miniature tri-axial fluxgate magnetometer with ring-core structure has a dynamic range of the Earth’s field ±65,000 nT, resolution of several nT. It has three independent parts placed in three perpendicular planes for measuring three orthogonal magnetic field components, respectively. A field-programmable gate array (FPGA) is used to generate stimulation signal, analog-to-digital (A/D) convertor control signal, and feedback digital-to-analog (D/A) control signal. Design and analysis details are given to improve the dynamic range, sensitivity, resolution, and linearity. Our prototype was measured and compared with a commercial standard Magson fluxgate magnetometer as a reference. The results show that our miniature fluxgate magnetometer can follow the Magson’s change trend well. When used as a magnetic compass, our prototype only has ± 0.3∘ deviation compared with standard magnetic compass.

  11. Miniaturized Charpy test for reactor pressure vessel embrittlement characterization

    Energy Technology Data Exchange (ETDEWEB)

    Manahan, M.P. Sr. [MPM Research and Consulting, Lemont, PA (United States)

    1999-10-01

    Modifications were made to a conventional Charpy machine to accommodate the miniaturized Charpy V-Notch (MCVN) specimens which were fabricated from an archived reactor pressure vessel (RPV) steel. Over 100 dynamic MCVN tests were performed and compared to the results from conventional Charpy V-Notch (CVN) tests to demonstrate the efficacy of the miniature specimen test. The optimized sidegrooved MCVN specimens exhibit transitional fracture behavior over essentially the same temperature range as the CVN specimens which indicates that the stress fields in the MCVN specimens reasonably simulate those of the CVN specimens and this fact has been observed in finite element calculations. This result demonstrates a significant breakthrough since it is now possible to measure the ductile-brittle transition temperature (DBTT) using miniature specimens with only small correction factors, and for some materials as in the present study, without the need for any correction factor at all. This development simplifies data interpretation and will facilitate future regulatory acceptance. The non-sidegrooved specimens yield energy-temperature data which is significantly shifted downward in temperature (non-conservative) as a result of the loss of constraint which accompanies size reduction.

  12. SMARBot: a modular miniature mobile robot platform

    Science.gov (United States)

    Meng, Yan; Johnson, Kerry; Simms, Brian; Conforth, Matthew

    2008-04-01

    Miniature robots have many advantages over their larger counterparts, such as low cost, low power, and easy to build a large scale team for complex tasks. Heterogeneous multi miniature robots could provide powerful situation awareness capability due to different locomotion capabilities and sensor information. However, it would be expensive and time consuming to develop specific embedded system for different type of robots. In this paper, we propose a generic modular embedded system architecture called SMARbot (Stevens Modular Autonomous Robot), which consists of a set of hardware and software modules that can be configured to construct various types of robot systems. These modules include a high performance microprocessor, a reconfigurable hardware component, wireless communication, and diverse sensor and actuator interfaces. The design of all the modules in electrical subsystem, the selection criteria for module components, and the real-time operating system are described. Some proofs of concept experimental results are also presented.

  13. On Landau Vlasov simulations of giant resonances

    International Nuclear Information System (INIS)

    Pi, M.; Schuck, P.; Suraud, E.; Gregoire, C.; Remaud, B.; Sebille, F.

    1987-05-01

    We present VUU calculations of giant resonances obtained in energetic heavy ion collisions. Also is considered the case of the giant dipole in 40 Ca and the possibility of studying the effects of rotation on such collective modes

  14. Reconstruction of the Midfoot Using a Free Vascularized Fibular Graft After En Bloc Excision for Giant Cell Tumor of the Tarsal Bones: A Case Report.

    Science.gov (United States)

    Hara, Hitomi; Kawamoto, Teruya; Onishi, Yasuo; Fujioka, Hiroyuki; Nishida, Kotaro; Kuroda, Ryosuke; Kurosaka, Masahiro; Akisue, Toshihiro

    2016-01-01

    We report the case of a 32-year-old Japanese female with a giant cell tumor of bone involving multiple midfoot bones. Giant cell tumors of bone account for approximately 5% of all primary bone tumors and most often arise at the ends of long bones. The small bones, such as those of the hands and feet, are rare sites for giant cell tumors. Giant cell tumors of the small bones tend to exhibit more aggressive clinical behavior than those of the long bones. The present patient underwent en bloc tumor excision involving multiple tarsals and metatarsals. We reconstructed the longitudinal arch of the foot with a free vascularized fibular graft. At the 2-year follow-up visit, bony union had been achieved, with no tumor recurrence. Copyright © 2016 American College of Foot and Ankle Surgeons. Published by Elsevier Inc. All rights reserved.

  15. Globally intertwined evolutionary history of giant barrel sponges

    Science.gov (United States)

    Swierts, Thomas; Peijnenburg, Katja T. C. A.; de Leeuw, Christiaan A.; Breeuwer, Johannes A. J.; Cleary, Daniel F. R.; de Voogd, Nicole J.

    2017-09-01

    Three species of giant barrel sponge are currently recognized in two distinct geographic regions, the tropical Atlantic and the Indo-Pacific. In this study, we used molecular techniques to study populations of giant barrel sponges across the globe and assessed whether the genetic structure of these populations agreed with current taxonomic consensus or, in contrast, whether there was evidence of cryptic species. Using molecular data, we assessed whether giant barrel sponges in each oceanic realm represented separate monophyletic lineages. Giant barrel sponges from 17 coral reef systems across the globe were sequenced for mitochondrial (partial CO1 and ATP6 genes) and nuclear (ATPsβ intron) DNA markers. In total, we obtained 395 combined sequences of the mitochondrial CO1 and ATP6 markers, which resulted in 17 different haplotypes. We compared a phylogenetic tree constructed from 285 alleles of the nuclear intron ATPsβ to the 17 mitochondrial haplotypes. Congruent patterns between mitochondrial and nuclear gene trees of giant barrel sponges provided evidence for the existence of multiple reproductively isolated species, particularly where they occurred in sympatry. The species complexes in the tropical Atlantic and the Indo-Pacific, however, do not form separate monophyletic lineages. This rules out the scenario that one species of giant barrel sponge developed into separate species complexes following geographic separation and instead suggests that multiple species of giant barrel sponges already existed prior to the physical separation of the Indo-Pacific and tropical Atlantic.

  16. A miniature spark counter for public communication and education

    International Nuclear Information System (INIS)

    Mao, C.H.; Weng, P.S.

    1987-01-01

    The fabrication of a miniature spark counter for public communication and education using naturally occurring radon as a radioactive source without involving any man-made radioactivity is described. The battery-powered miniature spark counter weighs 2.07 kg with a volume of 4.844 x 10/sup -4/ m/sup 3/. The circuitry consists of seven major components: timer, high-voltage power supply, attenuator, noninverting amplifier, low-pass filter, one-shot generator, and counter. Cellulose nitrate films irradiated with alpha particles from radon emanating from soil were etched and counted. The visible sparks during counting are rather heuristic, which can be used to demonstrate naturally occurring radioactivity in classrooms or showplaces

  17. Lobar holoprosencephaly in a Miniature Schnauzer with hypodipsic hypernatremia.

    Science.gov (United States)

    Sullivan, Stacey A; Harmon, Barry G; Purinton, P Thomas; Greene, Craig E; Glerum, Leigh E

    2003-12-15

    A 9-month-old male Miniature Schnauzer was examined because of a lifelong history of behavioral abnormalities, including hypodipsia. Diagnostic evaluation revealed marked hypernatremia and a single forebrain ventricle. The behavioral abnormalities did not resolve with correction of the hypernatremia, and the dog was euthanatized. At necropsy, midline forebrain structures were absent or reduced in size, and normally paired forebrain structures were incompletely separated. Findings were diagnostic for holoprosencephaly, a potentially genetic disorder and the likely cause of the hypodipsia. Similar evaluation of affected Miniature Schnauzer dogs may reveal whether holoprosencephaly routinely underlies the thirst deficiency that may be seen in dogs of this breed.

  18. Miniature Sensor for Aerosol Mass Measurements, Phase I

    Data.gov (United States)

    National Aeronautics and Space Administration — This SBIR project seeks to develop a miniature sensor for mass measurement of size-classified aerosols. A cascade impactor will be used to classify aerosol sample...

  19. Compounded natural convection enhancement in a vertical parallel-plate channel

    Energy Technology Data Exchange (ETDEWEB)

    Andreozzi, Assunta [Dipartimento di Energetica, Termofluidodinamica Applicata e Condizionamenti Ambientali, Universita degli Studi di Napoli Federico II, Piazzale Tecchio 80, 80125 Napoli (Italy); Campo, Antonio [Department of Mechanical Engineering, The University of Vermont, 33 Colchester Ave., Burlington, VT 05405 (United States); Manca, Oronzio [Dipartimento di Ingegneria Aerospaziale e Meccanica, Seconda Universita degli Studi di Napoli, via Roma 29, Aversa (CE) 81031 (Italy)

    2008-06-15

    This paper addresses the natural convection behavior of air when heated in single vertical, parallel-plate channels. To enhance the heat transfer two passive schemes are combined: (1) an equidistant short plate is inserted at the inlet and (2) two parallel, colinear insulated plates are appended at the exit. The channel plates are symmetrically heated with a uniform heat flux. The computational procedure is made by solving the full elliptic Navier-Stokes and energy equations with the finite-volume methodology in an I-type computational domain that is much larger than the physical domain. Within the framework of a ''proof-of-concept'' the controlling Grashof number based on the heated plate height ranges between 10{sup 3} and 10{sup 6}. The numerical velocity, pressure and temperature fields are post-processed to compute the quantities of engineering interest such as the induced mass flow rate, the pressure at the channel mid-plane and the temperature along the plates. In addition, the Nusselt number and the average Nusselt number, both based on the heated plate height, are presented in graphical form. At the end, optimal channel configurations expressed in terms of the highest average Nusselt number are obtained for the pair of pre-assigned Grashof numbers. (author)

  20. Treatment of lithic tumors of the distal ending of the radius: Results of two surgical techniques in a series of cases

    International Nuclear Information System (INIS)

    Escandon, Santiago; Soto, Camilo; Pulido, Edgar

    2003-01-01

    The distal ending of the radius can bear several tumors with different degrees of aggressiveness that depend on the extension of the tumor. Their treatment varies according to the aggressiveness it and can include curettage only or may require more extensive surgical procedures including, in some cases reconstructive surgery. The present study describes two surgical reconstructive techniques and their results in a series of cases. Five patients underwent radio-carpal, and three Ulnar-carpal arthrodesis with non-vascularized autologous bone graft from the iliac crest. Pathology diagnosis included: six giant cell tumors, one Ewing's sarcoma, and one chondroblastoma. There were five males and three females, with an average age of 34.6 years (rank: 17-52). All the patients underwent wide surgical resection of the tumor, and only the patient with the Ewing's sarcoma received additionally adjuvant chemotherapy and radiotherapy. Five patients had compromise of the surrounding soft tissues. Two had limitation of movement of the fingers, and one hypoesthesia. One patient with ulnar arthrodesis had a fracture of the cubitus, at the proximal ending of the plate, secondary to trauma. AII patients have been followed for an average time of 12.8 months (rank: 0.5-72). There have been no episodes of infection. Neither non-union of the osteotomies, nor failures of fixation or recurrences were observed

  1. Miniaturized radiation detector with custom synthesized diamond crystal as sensor

    International Nuclear Information System (INIS)

    Grobbelaar, J.H.; Burns, R.C.; Nam, T.L.; Keddy, R.J.

    1991-01-01

    A miniaturized detector consisting of three custom built hybrid circuits, a counter and a miniature high voltage power supply was designed to operate with custom synthesized Type Ib diamond crystals as sensors. Thick-film technology was incorporated in the circuit design. With a crystal having a volume of approximately 10 mm 3 and containing approximately 60 ppm paramagnetic nitrogen, the detector was capable of measuring γ-ray dose-rates as low as 7.5 μ Gy h -1 . The response characteristic was linear up to 1 cGy h -1 . (orig.)

  2. Multipole giant resonances in highly excited nuclei

    International Nuclear Information System (INIS)

    Xia Keding; Cai Yanhuang

    1989-01-01

    The isoscalar giant surface resonance and giant dipole resonance in highly excited nuclei are discussed. Excitation energies of the giant modes in 208 Pb are calculated in a simplified model, using the concept of energy wieghted sum rule (EWSR), and the extended Thomas-Fermi approximation at the finite temperature is employed to describe the finite temperature is employed to describe the finite temperature equilibrium state. It is shown that EWSR and the energy of the resonance depend only weakly on temperature in the system. This weak dependence is analysed

  3. Fabrication of miniaturized electrostatic deflectors using LIGA

    International Nuclear Information System (INIS)

    Jackson, K.H.; Khan-Malek, C.; Muray, L.P.

    1997-01-01

    Miniaturized electron beam columns (open-quotes microcolumnsclose quotes) have been demonstrated to be suitable candidates for scanning electron microscopy (SEM), e-beam lithography and other high resolution, low voltage applications. In the present technology, microcolumns consist of open-quotes selectively scaledclose quotes micro-sized lenses and apertures, fabricated from silicon membranes with e-beam lithography, reactive ion beam etching and other semiconductor thin-film techniques. These miniaturized electron-optical elements provide significant advantages over conventional optics in performance and ease of fabrication. Since lens aberrations scale roughly with size, it is possible to fabricate simple microcolumns with extremely high brightness sources and electrostatic objective lenses, with resolution and beam current comparable to conventional e-beam columns. Moreover since microcolumns typically operate at low voltages (1 KeV), the proximity effects encountered in e-beam lithography become negligible. For high throughput applications, batch fabrication methods may be used to build large parallel arrays of microcolumns. To date, the best reported performance with a 1 keV cold field emission cathode, is 30 nm resolution at a working distance of 2mm in a 3.5mm column. Fabrication of the microcolumn deflector and stigmator, however, have remained beyond the capabilities of conventional machining operations and semiconductor processing technology. This work examines the LIGA process as a superior alternative to fabrication of the deflectors, especially in terms of degree of miniaturization, dimensional control, placement accuracy, run-out, facet smoothness and choice of suitable materials. LIGA is a combination of deep X-ray lithography, electroplating, and injection molding processes which allow the fabrication of microstructures

  4. Evidence for deformation effect on the giant monopole resonance

    International Nuclear Information System (INIS)

    Buenerd, M.; Lebrun, D.; Martin, P.; de Saintignon, P.; Perrin, C.

    1980-01-01

    The giant monopole resonance in the region of deformed nuclei has been investigated by inelastic scattering of 108.5 MeV 3 He at very small scattering angles. Evidence is reported for coupling between the giant monopole and giant quadrupole vibrations, based both on energy shift and transition strength

  5. Swelling of U-7Mo/Al-Si dispersion fuel plates under irradiation – Non-destructive analysis of the AFIP-1 fuel plates

    Energy Technology Data Exchange (ETDEWEB)

    Wachs, D.M., E-mail: daniel.wachs@inl.gov [Idaho National Laboratory, Nuclear Fuels and Materials Division, P.O. Box 1625, Idaho Falls, ID 83415-6188 (United States); Robinson, A.B.; Rice, F.J. [Idaho National Laboratory, Characterization and Advanced PIE Division, P.O. Box 1625, Idaho Falls, ID 83415-6188 (United States); Kraft, N.C.; Taylor, S.C. [Idaho National Laboratory, Nuclear Fuels and Materials Division, P.O. Box 1625, Idaho Falls, ID 83415-6188 (United States); Lillo, M. [Idaho National Laboratory, Nuclear Systems Design and Analysis Division, P.O. Box 1625, Idaho Falls, ID 83415-6188 (United States); Woolstenhulme, N.; Roth, G.A. [Idaho National Laboratory, Nuclear Fuels and Materials Division, P.O. Box 1625, Idaho Falls, ID 83415-6188 (United States)

    2016-08-01

    Extensive fuel-matrix interactions leading to plate pillowing have proven to be a significant impediment to the development of a suitable high density low-enriched uranium molybdenum alloy (U-Mo) based dispersion fuel for high power applications in research reactors. The addition of silicon to the aluminum matrix was previously demonstrated to reduce interaction layer growth in mini-plate experiments. The AFIP-1 project involved the irradiation, in-canal examination, and post-irradiation examination of two fuel plates. The irradiation of two distinct full size, flat fuel plates (one using an Al-2wt%Si matrix and the other an Al-4043 (∼4.8 wt% Si) matrix) was performed in the INL ATR reactor in 2008–2009. The irradiation conditions were: ∼250 W/cm{sup 2} peak Beginning Of Life (BOL) power, with a ∼3.5e21 f/cm{sup 3} peak burnup. The plates were successfully irradiated and did not show any pillowing at the end of the irradiation. This paper reports the results and interpretation of the in-canal and post-irradiation non-destructive examinations that were performed on these fuel plates. It further compares additional PIE results obtained on fuel plates irradiated in contemporary campaigns in order to allow a complete comparison with all results obtained under similar conditions. Except for a brief indication of accelerated swelling early in the irradiation of the Al-2Si plate, the fuel swelling is shown to evolve linearly with the fission density through the maximum burnup.

  6. Fatal canine distemper virus infection of giant pandas in China.

    Science.gov (United States)

    Feng, Na; Yu, Yicong; Wang, Tiecheng; Wilker, Peter; Wang, Jianzhong; Li, Yuanguo; Sun, Zhe; Gao, Yuwei; Xia, Xianzhu

    2016-06-16

    We report an outbreak of canine distemper virus (CDV) infection among endangered giant pandas (Ailuropoda melanoleuca). Five of six CDV infected giant pandas died. The surviving giant panda was previously vaccinated against CDV. Genomic sequencing of CDV isolated from one of the infected pandas (giant panda/SX/2014) suggests it belongs to the Asia-1 cluster. The hemagglutinin protein of the isolated virus and virus sequenced from lung samples originating from deceased giant pandas all possessed the substitutions V26M, T213A, K281R, S300N, P340Q, and Y549H. The presence of the Y549H substitution is notable as it is found at the signaling lymphocytic activation molecule (SLAM) receptor-binding site and has been implicated in the emergence of highly pathogenic CDV and host switching. These findings demonstrate that giant pandas are susceptible to CDV and suggest that surveillance and vaccination among all captive giant pandas are warranted to support conservation efforts for this endangered species.

  7. Focal Segmental Glomerulosclerosis in Related Miniature Schnauzer Dogs.

    Science.gov (United States)

    Yau, Wilson; Mausbach, Lisa; Littman, Meryl P; Cianciolo, Rachel E; Brown, Cathy A

    2018-03-01

    Focal segmental glomerulosclerosis (FSGS) recently has been recognized as a common cause of proteinuria in dogs in general, and in Miniature Schnauzer dogs in particular. This study describes the morphologic features present in the kidneys of 8 related proteinuric Miniature Schnauzer dogs. The FSGS, characterized by solidification of portions of the capillary tuft, affected 32% to 49% of examined glomeruli in these dogs. Synechiae, often accompanied by hyalinosis, were present in 13% to 54% of glomeruli and were more prevalent in older dogs. Seven of 8 dogs had arteriolar hyalinosis. Ultrastructurally, all dogs had evidence of a podocytopathy in the absence of electron-dense deposits, glomerular basement membrane splitting, or fibrils. All dogs had multifocal to extensive podocyte foot process effacement. Other podocyte changes included microvillous transformation, the presence of vacuoles or protein resorption droplets, cytoplasmic electron-dense aggregates, and occasional binucleation. Variable amounts of intraglomerular lipid were present in all dogs. All dogs were proteinuric, with measured values for the urine protein-to-creatinine ratio ranging from 1.2 to 6.5. Azotemia was mild to absent and dogs were euthanatized at 5.1 to 14 years of age, in all cases due to nonrenal diseases. The underlying cause of FSGS in these Miniature Schnauzer dogs has yet to be determined, but contributors likely include genetic podocytopathy, lipid abnormalities, and glomerular hypertension.

  8. Giants among larges: how gigantism impacts giant virus entry into amoebae.

    Science.gov (United States)

    Rodrigues, Rodrigo Araújo Lima; Abrahão, Jônatas Santos; Drumond, Betânia Paiva; Kroon, Erna Geessien

    2016-06-01

    The proposed order Megavirales comprises the nucleocytoplasmic large DNA viruses (NCLDV), infecting a wide range of hosts. Over time, they co-evolved with different host cells, developing various strategies to penetrate them. Mimiviruses and other giant viruses enter cells through phagocytosis, while Marseillevirus and other large viruses explore endocytosis and macropinocytosis. These differing strategies might reflect the evolution of those viruses. Various scenarios have been proposed for the origin and evolution of these viruses, presenting one of the most enigmatic issues to surround these microorganisms. In this context, we believe that giant viruses evolved independently by massive gene/size gain, exploring the phagocytic pathway of entry into amoebas. In response to gigantism, hosts developed mechanisms to evade these parasites. Copyright © 2016 Elsevier Ltd. All rights reserved.

  9. Portable oral cancer detection using a miniature confocal imaging probe with a large field of view

    Science.gov (United States)

    Wang, Youmin; Raj, Milan; McGuff, H. Stan; Bhave, Gauri; Yang, Bin; Shen, Ting; Zhang, Xiaojing

    2012-06-01

    We demonstrate a MEMS micromirror enabled handheld confocal imaging probe for portable oral cancer detection, where a comparatively large field of view (FOV) was generated through the programmable Lissajous scanning pattern of the MEMS micromirror. Miniaturized handheld MEMS confocal imaging probe was developed, and further compared with the desktop confocal prototype under clinical setting. For the handheld confocal imaging system, optical design simulations using CODE VR® shows the lateral and axial resolution to be 0.98 µm and 4.2 µm, where experimental values were determined to be 3 µm and 5.8 µm, respectively, with a FOV of 280 µm×300 µm. Fast Lissajous imaging speed up to 2 fps was realized with improved Labview and Java based real-time imaging software. Properties such as 3D imaging through autofocusing and mosaic imaging for extended lateral view (6 mm × 8 mm) were examined for carcinoma real-time pathology. Neoplastic lesion tissues of giant cell fibroma and peripheral ossifying fibroma, the fibroma inside the paraffin box and ex vivo gross tissues were imaged by the bench-top and handheld imaging modalities, and further compared with commercial microscope imaging results. The MEMS scanner-based handheld confocal imaging probe shows great promise as a potential clinical tool for oral cancer diagnosis and treatment.

  10. Portable oral cancer detection using a miniature confocal imaging probe with a large field of view

    International Nuclear Information System (INIS)

    Wang, Youmin; Raj, Milan; Bhave, Gauri; Yang, Bin; Zhang, Xiaojing; McGuff, H. Stan; Shen, Ting

    2012-01-01

    We demonstrate a MEMS micromirror enabled handheld confocal imaging probe for portable oral cancer detection, where a comparatively large field of view (FOV) was generated through the programmable Lissajous scanning pattern of the MEMS micromirror. Miniaturized handheld MEMS confocal imaging probe was developed, and further compared with the desktop confocal prototype under clinical setting. For the handheld confocal imaging system, optical design simulations using CODE V R® shows the lateral and axial resolution to be 0.98 µm and 4.2 µm, where experimental values were determined to be 3 µm and 5.8 µm, respectively, with a FOV of 280 µm×300 µm. Fast Lissajous imaging speed up to 2 fps was realized with improved Labview and Java based real-time imaging software. Properties such as 3D imaging through autofocusing and mosaic imaging for extended lateral view (6 mm × 8 mm) were examined for carcinoma real-time pathology. Neoplastic lesion tissues of giant cell fibroma and peripheral ossifying fibroma, the fibroma inside the paraffin box and ex vivo gross tissues were imaged by the bench-top and handheld imaging modalities, and further compared with commercial microscope imaging results. The MEMS scanner-based handheld confocal imaging probe shows great promise as a potential clinical tool for oral cancer diagnosis and treatment. (paper)

  11. Literature review of giant gartersnake (Thamnophis gigas) biology and conservation

    Science.gov (United States)

    Halstead, Brian J.; Wylie, Glenn D.; Casazza, Michael L.

    2015-08-03

    This report reviews the available literature on giant gartersnakes (Thamnophis gigas) to compile existing information on this species and identify knowledge gaps that, if addressed, would help to inform conservation efforts for giant gartersnakes.  Giant gartersnakes comprise a species of semi-aquatic snake precinctive to wetlands in the Central Valley of California.  The diversion of surface water and conversion of wetlands to agricultural and other land uses resulted in the loss of more than 90 percent of natural giant gartersnake habitats.  Because of this habitat loss, giant gartersnakes are now listed by the United States and California Endangered Species Acts as Threatened.  Most extant populations occur in the rice-growing regions of the Sacramento Valley, which comprises the northern portion of the giant gartersnake’s former range.  The huge demand for water in California for agriculture, industry, recreation, and other human consumption, combined with periodic severe drought, places remaining giant gartersnake habitats at increased risk of degradation and loss.  This literature review summarizes the available information on giant gartersnake distribution, habitat relations, behavior, demography, and other aspects of its biology relevant to conservation.  This information is then compiled into a graphical conceptual model that indicates the importance of different aspects of giant gartersnake biology for maintaining positive population growth, and identifies those areas for which important information relevant for conservation is lacking.  Directing research efforts toward these aspects of giant gartersnake ecology will likely result in improvements to conserving this unique species while meeting the high demands for water in California.

  12. Collisional damping of giant monopole and quadrupole resonances

    International Nuclear Information System (INIS)

    Yildirim, S.; Gokalp, A.; Yilmaz, O.; Ayik, S.

    2001-01-01

    Collisional damping widths of giant monopole and quadrupole excitations for 120 Sn and 208 Pb at zero and finite temperatures are calculated within Thomas-Fermi approximation by employing the microscopic in-medium cross-sections of Li and Machleidt and the phenomenological Skyrme and Gogny forces, and are compared with each other. The results for the collisional widths of giant monopole and quadrupole vibrations at zero temperature as a function of the mass number show that the collisional damping of giant monopole vibrations accounts for about 30 - 40% of the observed widths at zero temperature, while for giant quadrupole vibrations it accounts for only 20 - 30% of the observed widths at zero temperature. (orig.)

  13. Giant cell phlebitis: a potentially lethal clinical entity.

    Science.gov (United States)

    Kunieda, Takeshige; Murayama, Masanori; Ikeda, Tsuneko; Yamakita, Noriyoshi

    2012-08-01

    An 83-year-old woman presented to us with a 4-week history of general malaise, subjective fever and lower abdominal pain. Despite the intravenous infusion of antibiotics, her blood results and physical condition worsened, resulting in her sudden death. Autopsy study revealed that the medium-sized veins of the mesentery were infiltrated by eosinophil granulocytes, lymphocytes, macrophages and multinucleated giant cells; however, the arteries were not involved. Microscopically, venous giant cell infiltration was observed in the gastrointestinal tract, bladder, retroperitoneal tissues and myocardium. The final diagnosis was giant cell phlebitis, a rare disease of unknown aetiology. This case demonstrates for the first time that giant cell phlebitis involving extra-abdominal organs, including hearts, can cause serious morbidity.

  14. Lateral deflection of the SOL plasma during a giant ELM

    International Nuclear Information System (INIS)

    Landman, I.S.; Wuerz, H.

    2001-01-01

    In recent H-mode experiments at JET with giant ELMs a lateral deflection of hot tokamak plasma striking the divertor plate has been observed. This deflection can effect the divertor erosion caused by the hot plasma irradiation. Based on the MHD model for the vapor shield plasma and the hot plasma, the Seebeck effect is analyzed for explanation of the deflection. At t=-∞ both plasmas are at rest and separated by a boundary parallel to the target. The interaction between plasmas develops gradually ('adiabatically') as exp(t/t 0 ) with t 0 ∼10 2 μs the ELM duration time. At inclined impact of the magnetized hot plasma a toroidal current develops in the interaction zone of the plasmas. The JxB force accelerates the interacting plasmas in the lateral direction. The cold plasma motion essentially compensates the current. The magnitude of the hot plasma deflection is comparable to the observed one

  15. Optimal and Miniaturized Strongly Coupled Magnetic Resonant Systems

    Science.gov (United States)

    Hu, Hao

    Wireless power transfer (WPT) technologies for communication and recharging devices have recently attracted significant research attention. Conventional WPT systems based either on far-field or near-field coupling cannot provide simultaneously high efficiency and long transfer range. The Strongly Coupled Magnetic Resonance (SCMR) method was introduced recently, and it offers the possibility of transferring power with high efficiency over longer distances. Previous SCMR research has only focused on how to improve its efficiency and range through different methods. However, the study of optimal and miniaturized designs has been limited. In addition, no multiband and broadband SCMR WPT systems have been developed and traditional SCMR systems exhibit narrowband efficiency thereby imposing strict limitations on simultaneous wireless transmission of information and power, which is important for battery-less sensors. Therefore, new SCMR systems that are optimally designed and miniaturized in size will significantly enhance various technologies in many applications. The optimal and miniaturized SCMR systems are studied here. First, analytical models of the Conformal SCMR (CSCMR) system and thorough analysis and design methodology have been presented. This analysis specifically leads to the identification of the optimal design parameters, and predicts the performance of the designed CSCMR system. Second, optimal multiband and broadband CSCMR systems are designed. Two-band, three-band, and four-band CSCMR systems are designed and validated using simulations and measurements. Novel broadband CSCMR systems are also analyzed, designed, simulated and measured. The proposed broadband CSCMR system achieved more than 7 times larger bandwidth compared to the traditional SCMR system at the same frequency. Miniaturization methods of SCMR systems are also explored. Specifically, methods that use printable CSCMR with large capacitors, novel topologies including meandered, SRRs, and

  16. Experimental induction of struvite uroliths in miniature schnauzer and beagle dogs.

    Science.gov (United States)

    Klausner, J S; Osborne, C A; O'Leary, T P; Muscoplat, C M; Griffith, D P

    1980-09-01

    Urease positive staphylococcal urinary tract infection was experimentally induced in 13 dogs. Eight dogs developed cystic and/or urethral struvite calculi in 2 to 8 weeks. No abnormalities in systemic cell mediated immunity were detected in dogs before or after the establishment of the urinary tract infection. Miniature schnauzers whose ancestors had developed stones seemed to be no more susceptible to experimental urinary tract infection and stone formation than miniature schnauzers or beagles whose ancestors did not develop stones.

  17. A new plate tectonic concept for the eastern-most Mediterranean

    Science.gov (United States)

    Huebscher, C.; McGrandle, A.; Scaife, G.; Spoors, R.; Stieglitz, T.

    2012-04-01

    Owing to the seismogenic faults bordering the Levant-Sinai realm and the discovery of giant gas reservoirs in the marine Levant Basin the scientific interest in this tectonically complex setting increased in recent years. Here we provide a new model for the Levant Basin architecture and adjacent plate boundaries emphasizing the importance of industrial seismic data for frontier research in earth science. PSDM seismics, residual gravity and depth to basement maps give a clear line of evidence that the Levant Basin, formerly considered as a single tectonic entity, is divided into two different domains. Highly stretched continental crust in the southern domain is separated from deeper and presumably Tethyan oceanic crust in the north. A transform continuing from southwest Cyprus to the Carmel Fault in northern Israel is considered as the boundary. If this interpretation holds, the Carmel-Cyprus Transform represents a yet unknown continent-ocean boundary in the eastern Mediterranean, thus adding new constrains for the Mediterranean plate tectonic puzzle. The Eratosthenes Seamount, considered as the spearhead of incipient continental collision in the eastern Mediterranean, is interpreted as a carbonate platform that developed above a volcanic basement. NW-SE trending strike-slip faults are abundant in the entire Levant region. Since this trend also shapes the topography of the Levant hinterland including Quaternary deposits their recent tectonic activity is quite likely. Thus, our study supports previous studies which attributed the evolution of submarine canyons and Holocene triggering of mass failures not only to salt tectonics or depositional processes, but also to active plate-tectonics.

  18. A new miniaturized negative-index meta-atom for tri-band applications

    Directory of Open Access Journals (Sweden)

    Hossain Mohammad Jakir

    2017-07-01

    Full Text Available In this paper, a miniature negative index meta-atom was designed; simulated, fabricated and measured based on parallel incidence of electromagnetic wave that can maintain a tri-band applications in microwave spectra. Compare to the other multi-band conventional metamaterial, the proposed meta-atom structure allows miniaturization factor and follows better effective medium ratio (EMR. Finite-integration technique (FIT based computer simulation technology (CST electromagnetic simulator was adopted to examine the design of the meta-atom. It exhibits tri-band response in conjunction with backward wave property over a certain frequency band in the microwave regime. Furthermore, the effective medium ratio is considerably improved compared to previously reported metamaterial. Moreover, few parametric analyses were done with the meta-atom. The size, scattering parameters and effective medium parameters of the proposed negative index miniaturized meta-atom is appropriate for tri-band applications.

  19. Giant Clams and Rising CO2: Light May Ameliorate Effects of Ocean Acidification on a Solar-Powered Animal.

    Directory of Open Access Journals (Sweden)

    Sue-Ann Watson

    Full Text Available Global climate change and ocean acidification pose a serious threat to marine life. Marine invertebrates are particularly susceptible to ocean acidification, especially highly calcareous taxa such as molluscs, echinoderms and corals. The largest of all bivalve molluscs, giant clams, are already threatened by a variety of local pressures, including overharvesting, and are in decline worldwide. Several giant clam species are listed as 'Vulnerable' on the IUCN Red List of Threatened Species and now climate change and ocean acidification pose an additional threat to their conservation. Unlike most other molluscs, giant clams are 'solar-powered' animals containing photosynthetic algal symbionts suggesting that light could influence the effects of ocean acidification on these vulnerable animals. In this study, juvenile fluted giant clams Tridacna squamosa were exposed to three levels of carbon dioxide (CO2 (control ~400, mid ~650 and high ~950 μatm and light (photosynthetically active radiation 35, 65 and 304 μmol photons m-2 s-1. Elevated CO2 projected for the end of this century (~650 and ~950 μatm reduced giant clam survival and growth at mid-light levels. However, effects of CO2 on survival were absent at high-light, with 100% survival across all CO2 levels. Effects of CO2 on growth of surviving clams were lessened, but not removed, at high-light levels. Shell growth and total animal mass gain were still reduced at high-CO2. This study demonstrates the potential for light to alleviate effects of ocean acidification on survival and growth in a threatened calcareous marine invertebrate. Managing water quality (e.g. turbidity and sedimentation in coastal areas to maintain water clarity may help ameliorate some negative effects of ocean acidification on giant clams and potentially other solar-powered calcifiers, such as hard corals.

  20. Giant Clams and Rising CO2: Light May Ameliorate Effects of Ocean Acidification on a Solar-Powered Animal.

    Science.gov (United States)

    Watson, Sue-Ann

    2015-01-01

    Global climate change and ocean acidification pose a serious threat to marine life. Marine invertebrates are particularly susceptible to ocean acidification, especially highly calcareous taxa such as molluscs, echinoderms and corals. The largest of all bivalve molluscs, giant clams, are already threatened by a variety of local pressures, including overharvesting, and are in decline worldwide. Several giant clam species are listed as 'Vulnerable' on the IUCN Red List of Threatened Species and now climate change and ocean acidification pose an additional threat to their conservation. Unlike most other molluscs, giant clams are 'solar-powered' animals containing photosynthetic algal symbionts suggesting that light could influence the effects of ocean acidification on these vulnerable animals. In this study, juvenile fluted giant clams Tridacna squamosa were exposed to three levels of carbon dioxide (CO2) (control ~400, mid ~650 and high ~950 μatm) and light (photosynthetically active radiation 35, 65 and 304 μmol photons m-2 s-1). Elevated CO2 projected for the end of this century (~650 and ~950 μatm) reduced giant clam survival and growth at mid-light levels. However, effects of CO2 on survival were absent at high-light, with 100% survival across all CO2 levels. Effects of CO2 on growth of surviving clams were lessened, but not removed, at high-light levels. Shell growth and total animal mass gain were still reduced at high-CO2. This study demonstrates the potential for light to alleviate effects of ocean acidification on survival and growth in a threatened calcareous marine invertebrate. Managing water quality (e.g. turbidity and sedimentation) in coastal areas to maintain water clarity may help ameliorate some negative effects of ocean acidification on giant clams and potentially other solar-powered calcifiers, such as hard corals.

  1. Miniaturization of high-energy physics detectors. Vol. 14

    International Nuclear Information System (INIS)

    Stefanini, A.

    1983-01-01

    Continued experimental research in high-energy physics requires the reduction in size and cost of the advanced technical equipment involved. A new technology is rapidly evolving that promises to replace today's massive high-energy physics instruments--which may be composed of several thousand tons of sensitive parts--with miniaturized equivalents. Smaller, less expensive apparatus would create more opportunities for research worldwide, and many types of experiments now considered impractical could then be carried out. Scientists and engineers from many countries have contributed to this volume to provide a broad panorama of the new miniaturization technology in high-energy physics. They describe a wide range of new instruments and their applications, discuss limitations and technological problems, and explore the connections between technology and progress in the field of high-energy physics

  2. Multispin giant magnons

    International Nuclear Information System (INIS)

    Bobev, N. P.; Rashkov, R. C.

    2006-01-01

    We investigate giant magnons from classical rotating strings in two different backgrounds. First we generalize the solution of Hofman and Maldacena and investigate new magnon excitations of a spin chain which are dual to a string on RxS 5 with two nonvanishing angular momenta. Allowing string dynamics along the third angle in the five sphere, we find a dispersion relation that reproduces the Hofman and Maldacena one and the one found by Dorey for the two spin case. In the second part of the paper we generalize the two 'spin' giant magnon to the case of β-deformed AdS 5 xS 5 background. We find agreement between the dispersion relation of the rotating string and the proposed dispersion relation of the magnon bound state on the spin chain

  3. Numerical Study on the Effect of Distribution Plates in the Manifolds on the Flow Distribution and Thermal Performance of a Flat Plate Solar Collector

    Directory of Open Access Journals (Sweden)

    Juan Manuel García-Guendulain

    2018-04-01

    Full Text Available Flow maldistribution represents a problem of particular interest in the engineering field for several thermal systems. In flat plate solar collectors, the thermal efficiency strongly depends on the flow distribution through the riser tubes, where a uniform distribution causes a uniform temperature distribution and therefore a higher efficiency. In this work, a Computational Fluid Dynamics (CFD numerical analysis has been carried out using the commercial software FLUENT®, in order to determine the flow distribution, pressure drop and hence the thermal efficiency of a solar collector with distribution flow plates inside the manifolds. The obtained numerical solution for this type of thermal systems has been validated with experimental results available in literature for laminar and turbulent flow. Four distribution plate configurations were analyzed. Results show that using two distribution plates in each of both manifolds improves the flow uniformity up to 40% under the same operating conditions when distribution plates are not used. Besides, it is shown that there exists an increase in the overall pressure drop which is practically negligible for the tilt angles commonly employed in the installation of flat plate solar collectors in Mexico. The use of closed end distribution plates on the dividing and combining manifolds allows the thermal efficiency to become close to the ideal thermal efficiency which is obtained with a uniform flow distribution.

  4. Surgical Treatment, Oral Rehabilitation, and Orthognathic Surgery After Failure of Pharmacologic Treatment of Central Giant Cell Lesion: A Case Report.

    Science.gov (United States)

    Maia Nogueira, Renato Luiz; Osterne, Rafael Lima Verde; Cavalcante, Roberta Barroso; Abreu, Ricardo Teixeira

    2016-12-01

    Although pharmacologic treatments for central giant cell lesions have gained much emphasis, these treatment modalities do not always have successful outcomes, and surgical treatment may be necessary. The purpose of the present study was to report a case of aggressive central giant cell lesion initially treated by nonsurgical methods without satisfactory results, necessitating segmental mandibular resection for definitive treatment and oral rehabilitation. A 20-year-old woman was diagnosed with an aggressive central giant cell lesion in the mandible. The patient was first treated with intralesional corticosteroid injections. Subsequently, the lesion increased in size. Therefore, a second pharmacologic treatment was proposed with salmon calcitonin nasal spray, but no signs of a treatment response were noted. Because of the lack of response, surgical excision was performed, and a mandibular reconstruction plate was installed. At 12 months after surgical resection, the patient underwent mandibular reconstruction with bone grafts. After 6 months, 7 dental implants were installed, and fixed prostheses were made. After installation of the prostheses, the patient experienced persistent mandibular laterognathism, and a mandibular orthognathic surgery was performed to correct the laterognathia. The follow-up examination 4 years after orthognathic surgery showed no signs of recurrence and good facial symmetry. Copyright © 2016 American Association of Oral and Maxillofacial Surgeons. Published by Elsevier Inc. All rights reserved.

  5. A Miniature Coupled Bistable Vibration Energy Harvester

    International Nuclear Information System (INIS)

    Zhu, D; Arthur, D C; Beeby, S P

    2014-01-01

    This paper reports the design and test of a miniature coupled bistable vibration energy harvester. Operation of a bistable structure largely depends on vibration amplitude rather than frequency, which makes it very promising for wideband vibration energy harvesting applications. A coupled bistable structure consists of a pair of mobile magnets that create two potential wells and thus the bistable phenomenon. It requires lower excitation to trigger bistable operation compared to conventional bistable structures. Based on previous research, this work focused on miniaturisation of the coupled bistable structure for energy harvesting application. The proposed bistable energy harvester is a combination of a Duffing's nonlinear structure and a linear assisting resonator. Experimental results show that the output spectrum of the miniature coupled bistable vibration energy harvester was the superposition of several spectra. It had a higher maximum output power and a much greater bandwidth compared to simply the Duffing's structure without the assisting resonator

  6. Baking process of thin plate carbonaceous compact

    Energy Technology Data Exchange (ETDEWEB)

    Suzuki, Yoshio; Shimada, Toyokazu

    1987-06-27

    As a production process of a thin plate carbonaceous compact for separator of phosphoric acid fuel cell, there is a process to knead carbonaceous powder and thermosetting resin solution, to form and harden the kneaded material and then to bake, carbonize and graphitize it. However in this baking and carbonization treatment, many thin plate compacts are set in a compiled manner within a heating furnace and receive a heat treatment from their circumference. Since the above compacts to be heated tend generally to be heated from their peripheries, their baked conditions are not homogeneous easily causing the formation of cracks, etc.. As a process to heat and bake homogeneously by removing the above problematical points, this invention offers a process to set in a heating furnace a laminate consisting of the lamination of thin plate carbonaceous compacts and the heat resistant soaking plates which hold the upper and lower ends of the above lamination, to fill the upper and under peripheries of the laminate above with high heat conductive packing material and its side periphery with low heat conductive packing material respectively and to heat and sinter it. In addition, the invention specifies the high and low heat conductive packing materials respectively. (1 fig, 2 tabs)

  7. Giant Congenital Melanocytic Naevi: review of literature

    Directory of Open Access Journals (Sweden)

    A. Marchesi

    2012-04-01

    Full Text Available giant congenital pigmented naevi is a great reconstructive challenge for the pediatric and plastic surgeons. due to the increased risk of malignant transformation in such lesions, many procedures have been used to remove giant congenital naevi like dermoabrasion, laser treatment or surgical excision combined with reconstruction through skin expansion or skin grafting; among these, only a complete excision can offer an efficacious treatment. in our centre we use the “tissue expansion” technique in order to achieve a sufficient quantity of normal skin to perform a both staged and radical excision of these giant lesions.

  8. Naturalism and Mannerism in Indian Miniatures

    Science.gov (United States)

    Duran, Jane

    2001-01-01

    In this essay, the author furthers the argument that critical commentary on the Rajput and Muslim miniatures of India has focused on a rather odd use of labels and categories, perhaps to an even greater extent than has been the case with much of the rest of the criticism of the art of South Asia. She first examines the use of the term…

  9. Fatal canine distemper virus infection of giant pandas in China

    Science.gov (United States)

    Feng, Na; Yu, Yicong; Wang, Tiecheng; Wilker, Peter; Wang, Jianzhong; Li, Yuanguo; Sun, Zhe; Gao, Yuwei; Xia, Xianzhu

    2016-01-01

    We report an outbreak of canine distemper virus (CDV) infection among endangered giant pandas (Ailuropoda melanoleuca). Five of six CDV infected giant pandas died. The surviving giant panda was previously vaccinated against CDV. Genomic sequencing of CDV isolated from one of the infected pandas (giant panda/SX/2014) suggests it belongs to the Asia-1 cluster. The hemagglutinin protein of the isolated virus and virus sequenced from lung samples originating from deceased giant pandas all possessed the substitutions V26M, T213A, K281R, S300N, P340Q, and Y549H. The presence of the Y549H substitution is notable as it is found at the signaling lymphocytic activation molecule (SLAM) receptor-binding site and has been implicated in the emergence of highly pathogenic CDV and host switching. These findings demonstrate that giant pandas are susceptible to CDV and suggest that surveillance and vaccination among all captive giant pandas are warranted to support conservation efforts for this endangered species. PMID:27310722

  10. Giant urinary bladder calculus: Case report | Otieno | East African ...

    African Journals Online (AJOL)

    A vertical calculus weighing more than 100 g is categorised as a giant urinary bladder stone. Giant urinary bladder stones are very rare and very few cases have been reported in English literature and only one case from Africa. This is a case report of a patient with a giant urinary bladder calculus presenting as a rectal ...

  11. Miniaturization of Fresnel lenses for solar concentration: a quantitative investigation.

    Science.gov (United States)

    Duerr, Fabian; Meuret, Youri; Thienpont, Hugo

    2010-04-20

    Sizing down the dimensions of solar concentrators for photovoltaic applications offers a number of promising advantages. It provides thinner modules and smaller solar cells, which reduces thermal issues. In this work a plane Fresnel lens design is introduced that is first analyzed with geometrical optics. Because of miniaturization, pure ray tracing may no longer be valid to determine the concentration performance. Therefore, a quantitative wave optical analysis of the miniaturization's influence on the obtained concentration performance is presented. This better quantitative understanding of the impact of diffraction in microstructured Fresnel lenses might help to optimize the design of several applications in nonimaging optics.

  12. Giant cell angiofibroma or localized periorbital lymphedema?

    Science.gov (United States)

    Lynch, Michael C; Chung, Catherine G; Specht, Charles S; Wilkinson, Michael; Clarke, Loren E

    2013-12-01

    Giant cell angiofibroma represents a rare soft tissue neoplasm with a predilection for the orbit. We recently encountered a mass removed from the lower eyelid of a 56-year-old female that histopathologically resembled giant cell angiofibroma. The process consisted of haphazardly arranged CD34-positive spindled and multinucleated cells within an edematous, densely vascular stroma. However, the patient had recently undergone laryngectomy and radiotherapy for a laryngeal squamous cell carcinoma. A similar mass had arisen on the contralateral eyelid, and both had developed several months post-therapy. Lymphedema of the orbit can present as tumor-like nodules and in some cases may share histopathologic features purported to be characteristic of giant cell angiofibroma. A relationship between giant cell angiofibroma and lymphedema has not been established, but our case suggests there may be one. The potential overlap of these two conditions should be recognized, as should other entities that may enter the differential diagnosis. © 2013 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  13. [Giant paraovarian cyst in childhood - Case report].

    Science.gov (United States)

    Torres, Janina P; Íñiguez, Rodrigo D

    2015-01-01

    Paraovarian cysts are very uncommon in children To present a case of giant paraovarian cyst case in a child and its management using a modified laparoscopic-assisted technique A 13-year-old patient with a 15 day-history of intermittent abdominal pain, located in the left hemiabdomen and associated with progressive increase in abdominal volume. Diagnostic imaging was inconclusive, describing a giant cystic formation that filled up the abdomen, but without specifying its origin. Laboratory tests and tumor markers were within normal range. Video-assisted transumbilical cystectomy, a modified laparoscopic procedure with diagnostic and therapeutic intent, was performed with a successful outcome. The histological study reported giant paraovarian cyst. Cytology results were negative for tumor cells. The patient remained asymptomatic during the postoperative follow-up. The video-assisted transumbilical cystectomy is a safe procedure and an excellent diagnostic and therapeutic alternative for the treatment of giant paraovarian cysts. Copyright © 2015. Publicado por Elsevier España, S.L.U.

  14. [Tissular expansion in giant congenital nevi treatment].

    Science.gov (United States)

    Nguyen Van Nuoi, V; Francois-Fiquet, C; Diner, P; Sergent, B; Zazurca, F; Franchi, G; Buis, J; Vazquez, M-P; Picard, A; Kadlub, N

    2014-08-01

    Surgical management of giant melanotic naevi remains a surgical challenge. Tissue expansion provides tissue of the same quality for the repair of defects. The aim of this study is to review tissular expansion for giant melanotic naevi. We conducted a retrospective study from 2000 to 2012. All children patients who underwent a tissular expansion for giant congenital naevi had been included. Epidemiological data, surgical procedure, complication rate and results had been analysed. Thirty-tree patients had been included; they underwent 61 procedures with 79 tissular-expansion prosthesis. Previous surgery, mostly simple excision had been performed before tissular expansion. Complete naevus excision had been performed in 63.3% of the cases. Complications occurred in 45% of the cases, however in 50% of them were minor. Iterative surgery increased the complication rate. Tissular expansion is a valuable option for giant congenital naevus. However, complication rate remained high, especially when iterative surgery is needed. Copyright © 2013 Elsevier Masson SAS. All rights reserved.

  15. Long-term (60-month results for the implantable miniature telescope: efficacy and safety outcomes stratified by age in patients with end-stage age-related macular degeneration

    Directory of Open Access Journals (Sweden)

    Boyer D

    2015-06-01

    Full Text Available David Boyer,1 K Bailey Freund,2 Carl Regillo,3 Marc H Levy,4 Sumit Garg5 1Retina-Vitreous Associates Medical Group, Beverly Hills, CA, 2Vitreous-Retina-Macula Consultants of New York, New York, NY; 3Wills Eye Institute, Philadelphia, PA, 4Sarasota Retina Institute, Sarasota, FL, 5The Gavin Herbert Eye Institute (University of California, Irvine Irvine, CA, USA Background: The purpose of this study was to evaluate the long-term results of an implantable miniature telescope (IMT in patients with bilateral, end-stage, age-related macular degeneration (AMD.Methods: A prospective, open-label, multicenter clinical trial with fellow eye controls enrolled 217 patients (mean age 76 years with AMD and moderate-to-profound bilateral central visual acuity loss (20/80–20/800 resulting from untreatable geographic atrophy, disciform scars, or both. A subgroup analysis was performed with stratification for age (patient age 65 to <75 years [group 1; n=70] and patient age ≥75 years [group 2; n=127], with a comparative evaluation of change in best-corrected distance visual acuity (BCDVA, quality of life, ocular complications from surgery, adverse events, and endothelial cell density (ECD. Follow-up in an extension study was 60 months.Results: Data were available for 22, 38, and 31 patients in group 1 and 42, 46, and 32 patients in group 2 at 36, 48, and 60 months, respectively. Mean BCDVA improvement from baseline to 60 months was 2.41±2.69 lines in all patients (n=76, with 2.64±2.55 lines in group 1 and 2.09±2.88 lines in group 2. Quality of life scores were significantly higher in group 1. The most common significant surgery-related ocular complications in group 1 were iritis >30 days after surgery (7/70; 10% and persistent corneal edema (3/70; 4.3%; and in group 2 were a decrease in BCDVA in the implanted eye or IMT removal (10/127 each; 7.9%, corneal edema >30 days after surgery (9/127; 7.1%, and persistent corneal edema (6/127; 4.7%. Significant

  16. Evaluation of a miniature magnetostrictive actuator using Galfenol under tensile stress

    International Nuclear Information System (INIS)

    Ueno, Toshiyuki; Miura, Hidemitsu; Yamada, Sotoshi

    2011-01-01

    We are, at present, developing miniature actuators using an iron-gallium alloy (Galfenol). Galfenol is an iron-based magnetostrictive material with magnetostriction exceeding 200 ppm, Young's modulus of 70 GPa and a high relative permeability (>100). The advantages of an actuator using this material are capability of miniaturization, stability against external force, low voltage driving and high power. In this study, a miniature vibrator using an E core of Galfenol under tensile stress up to 20 MPa was investigated. The vibrator did not fracture and maintained the magnetostriction even under a high tensile stress. In addition, the resonance frequency, unchanged under the tensile stress, was lower than the cutoff frequency, hence the vibrator can be driven with a low voltage even in resonance driving. The temperature rise in resonance driving was low and creep was not observed in resonance driving under tensile stress. The vibrator will be applicable in flat panel or bone conductive speakers.

  17. Evaluation of a miniature magnetostrictive actuator using Galfenol under tensile stress

    Science.gov (United States)

    Ueno, Toshiyuki; Miura, Hidemitsu; Yamada, Sotoshi

    2011-02-01

    We are, at present, developing miniature actuators using an iron-gallium alloy (Galfenol). Galfenol is an iron-based magnetostrictive material with magnetostriction exceeding 200 ppm, Young's modulus of 70 GPa and a high relative permeability (>100). The advantages of an actuator using this material are capability of miniaturization, stability against external force, low voltage driving and high power. In this study, a miniature vibrator using an E core of Galfenol under tensile stress up to 20 MPa was investigated. The vibrator did not fracture and maintained the magnetostriction even under a high tensile stress. In addition, the resonance frequency, unchanged under the tensile stress, was lower than the cutoff frequency, hence the vibrator can be driven with a low voltage even in resonance driving. The temperature rise in resonance driving was low and creep was not observed in resonance driving under tensile stress. The vibrator will be applicable in flat panel or bone conductive speakers.

  18. Nanoparticle separation with a miniaturized asymmetrical flow field-flow fractionation cartridge

    Science.gov (United States)

    Müller, David; Cattaneo, Stefano; Meier, Florian; Welz, Roland; deMello, Andrew

    2015-07-01

    Asymmetrical Flow Field-Flow Fractionation (AF4) is a separation technique applicable to particles over a wide size range. Despite the many advantages of AF4, its adoption in routine particle analysis is somewhat limited by the large footprint of currently available separation cartridges, extended analysis times and significant solvent consumption. To address these issues, we describe the fabrication and characterization of miniaturized AF4 cartridges. Key features of the scale-down platform include simplified cartridge and reagent handling, reduced analysis costs and higher throughput capacities. The separation performance of the miniaturized cartridge is assessed using certified gold and silver nanoparticle standards. Analysis of gold nanoparticle populations indicates shorter analysis times and increased sensitivity compared to conventional AF4 separation schemes. Moreover, nanoparticulate titanium dioxide populations exhibiting broad size distributions are analyzed in a rapid and efficient manner. Finally, the repeatability and reproducibility of the miniaturized platform are investigated with respect to analysis time and separation efficiency.

  19. AGB [asymptotic giant branch]: Star evolution

    International Nuclear Information System (INIS)

    Becker, S.A.

    1987-01-01

    Asymptotic giant branch stars are red supergiant stars of low-to-intermediate mass. This class of stars is of particular interest because many of these stars can have nuclear processed material brought up repeatedly from the deep interior to the surface where it can be observed. A review of recent theoretical and observational work on stars undergoing the asymptotic giant branch phase is presented. 41 refs

  20. Cold plate

    Energy Technology Data Exchange (ETDEWEB)

    Marroquin, Christopher M.; O' Connell, Kevin M.; Schultz, Mark D.; Tian, Shurong

    2018-02-13

    A cold plate, an electronic assembly including a cold plate, and a method for forming a cold plate are provided. The cold plate includes an interface plate and an opposing plate that form a plenum. The cold plate includes a plurality of active areas arranged for alignment over respective heat generating portions of an electronic assembly, and non-active areas between the active areas. A cooling fluid flows through the plenum. The plenum, at the non-active areas, has a reduced width and/or reduced height relative to the plenum at the active areas. The reduced width and/or height of the plenum, and exterior dimensions of cold plate, at the non-active areas allow the non-active areas to flex to accommodate surface variations of the electronics assembly. The reduced width and/or height non-active areas can be specifically shaped to fit between physical features of the electronics assembly.

  1. Discovery of Japan’s Oldest Photographic Plates of a Starfield

    Science.gov (United States)

    Watanabe, Jun-ichi; Sasaki, Goro; Nakagiri, Masao; Ohshima, Norio

    2015-08-01

    The Public Outreach and Archive Office in NAOJ has been inspecting as many as 20,000 old photographic plates, which were found in a pile of cardboard cartons. In the course of their inspections, we have discovered 437 plates recorded from the end of the 19th century to the beginning of the 20th century. This was the first era in which observations were recorded using photographic plates in Japan.Most of the plates were obtained by using the Brashear astrograph at Azabubu in the 19th century. The oldest photographic plate was marked (delete ‘as’) No.13 and was recorded on March 5, 1899. We also found a number of historically important plates; among these are images of the first minor planet “TOKIO” that was detected in Japan and named after our country, and of a star 61 Cyg, with a large proper motion.We have long known that Tokyo Observatory of Tokyo Imperial University began its observations at Azabu. However, for many years, everyone believed that all the plates and observational instruments were lost in the chaos following the Great Kanto earthquake (1923) and in a fire that damaged Tokyo Observatory’s main building during the World War II, events that took place before and after the Observatory’s move to Mitaka. We made a catalogue of these plates and will present some statistics along with our effort for archives in our observatory.

  2. Metallographic examination of a failed Jewett nail-plate from a human femur

    International Nuclear Information System (INIS)

    Gray, R.J.; Zirkel, L.G. Jr.

    1976-01-01

    A type 316L wrought stainless steel Jewett nail-plate is one of several implant designs for bridging fractures in the proximal end of the femur. A soldier received a high velocity projectile in the trochanteric region of the femur. He was treated for a subtrochanteric fracture and greater trochanteric bone loss. After 9 months, hip varus angulation was progressively increasing. A Jewett nail-plate was inserted after valgus osteotomy and bone grafting of the unhealed fracture. The nail-plate fractured three weeks after surgery. Optical and scanning electron microscopy related the origin of failure to an impactor failure and subsequent microscopic scoring of the nail-plate during insertion into the abnormally hard femoral head. Photomicrographs showing the implant failure and evidences of corrosion after the short time in the body are presented. 12 figs

  3. Miniature scientific-grade magnetic sensors for CubeSats

    Science.gov (United States)

    Pronenko, Vira; Belyayev, Serhiy

    2016-07-01

    Micro- and nanosatellites have become more attractive due to their low development and launch cost. A class of nanosatellites defined by the CubeSat standard allows standardizing CubeSat preparation and launch, thus making the projects more affordable. Because of the complexity of sensors miniaturization to install them onboard CubeSat, the majority of CubeSat launches are aimed the technology demonstration or education missions. The scientific success of CubeSat mission depends on the sensors quality. In spite that the sensitivity of the magnetic sensors strongly depends on their size, the recent development in this branch allows us to propose tiny but sensitive both AC and DC magnetometers. The goal of the present report is to introduce the new design of miniature three-component sensors for measurement of vector magnetic fields - for quasi-stationary and slowly fluctuating - flux-gate magnetometer (FGM) - and for alternative ones - search-coil magnetometer (SCM). In order to create magnetometers with the really highest possible level of parameters, a set of scientific and technological problems, mostly aimed at the sensor construction improvement, was solved. The most important parameter characterizing magnetometer quality is its own magnetic noise level (NL). The analysis of the NL influencing factors is made and the ways to decrease it are discussed in the report. Construction details and technical specifications of miniature but sensitive FGM and SCM for the CubeSat mission are presented. This work is supported by EC Framework 7 funded project 607197.

  4. Predictive Surface Roughness Model for End Milling of Machinable Glass Ceramic

    Energy Technology Data Exchange (ETDEWEB)

    Reddy, M Mohan; Gorin, Alexander [School of Engineering and Science, Curtin University of Technology, Sarawak (Malaysia); Abou-El-Hossein, K A, E-mail: mohan.m@curtin.edu.my [Mechanical and Aeronautical Department, Nelson Mandela Metropolitan University, Port Elegebeth, 6031 (South Africa)

    2011-02-15

    Advanced ceramics of Machinable glass ceramic is attractive material to produce high accuracy miniaturized components for many applications in various industries such as aerospace, electronics, biomedical, automotive and environmental communications due to their wear resistance, high hardness, high compressive strength, good corrosion resistance and excellent high temperature properties. Many research works have been conducted in the last few years to investigate the performance of different machining operations when processing various advanced ceramics. Micro end-milling is one of the machining methods to meet the demand of micro parts. Selecting proper machining parameters are important to obtain good surface finish during machining of Machinable glass ceramic. Therefore, this paper describes the development of predictive model for the surface roughness of Machinable glass ceramic in terms of speed, feed rate by using micro end-milling operation.

  5. Predictive Surface Roughness Model for End Milling of Machinable Glass Ceramic

    International Nuclear Information System (INIS)

    Reddy, M Mohan; Gorin, Alexander; Abou-El-Hossein, K A

    2011-01-01

    Advanced ceramics of Machinable glass ceramic is attractive material to produce high accuracy miniaturized components for many applications in various industries such as aerospace, electronics, biomedical, automotive and environmental communications due to their wear resistance, high hardness, high compressive strength, good corrosion resistance and excellent high temperature properties. Many research works have been conducted in the last few years to investigate the performance of different machining operations when processing various advanced ceramics. Micro end-milling is one of the machining methods to meet the demand of micro parts. Selecting proper machining parameters are important to obtain good surface finish during machining of Machinable glass ceramic. Therefore, this paper describes the development of predictive model for the surface roughness of Machinable glass ceramic in terms of speed, feed rate by using micro end-milling operation.

  6. Nutritional evaluation of the giant grassropper (Zonocerus ...

    African Journals Online (AJOL)

    The biological value of giant grasshopper protein (Zonocerus variegatus) was evaluated by comparing the weight gained, food efficiency ratio (FER), protein efficiency ratio (PER) of rats fed standard laboratory chow with that of rats fed giant grasshopper, Soyabean(Glycine max) and crayfish. The effect of high fibre content ...

  7. A Front-End ASIC with Receive Sub-array Beamforming Integrated with a 32 × 32 PZT Matrix Transducer for 3-D Transesophageal Echocardiography

    NARCIS (Netherlands)

    Chen, C.; Chen, Z.; Bera, Deep; Raghunathan, S.B.; ShabaniMotlagh, M.; Noothout, E.C.; Chang, Z.Y.; Ponte, Jacco; Prins, Christian; Vos, H.J.; Bosch, Johan G.; Verweij, M.D.; de Jong, N.; Pertijs, M.A.P.

    2017-01-01

    This paper presents a power-and area-efficient front-end application-specific integrated circuit (ASIC) that is directly integrated with an array of 32 × 32 piezoelectric transducer elements to enable next-generation miniature ultrasound probes for real-time 3-D transesophageal echocardiography.

  8. RE-INFLATED WARM JUPITERS AROUND RED GIANTS

    Energy Technology Data Exchange (ETDEWEB)

    Lopez, Eric D. [Institute for Astronomy, Royal Observatory Edinburgh, University of Edinburgh, Blackford Hill, Edinburgh (United Kingdom); Fortney, Jonathan J. [Department of Astronomy and Astrophysics, University of California, Santa Cruz, CA 95064 (United States)

    2016-02-10

    Since the discovery of the first transiting hot Jupiters, models have sought to explain the anomalously large radii of highly irradiated gas giants. We now know that the size of hot Jupiter radius anomalies scales strongly with a planet's level of irradiation and numerous models like tidal heating, ohmic dissipation, and thermal tides have since been developed to help explain these inflated radii. In general, however, these models can be grouped into two broad categories: models that directly inflate planetary radii by depositing a fraction of the incident irradiation into the interior and models that simply slow a planet's radiative cooling, allowing it to retain more heat from formation and thereby delay contraction. Here we present a new test to distinguish between these two classes of models. Gas giants orbiting at moderate orbital periods around post-main-sequence stars will experience enormous increases to their irradiation as their host stars move up the sub-giant and red-giant branches. If hot Jupiter inflation works by depositing irradiation into the planet's deep interiors then planetary radii should increase in response to the increased irradiation. This means that otherwise non-inflated gas giants at moderate orbital periods of >10 days can re-inflate as their host stars evolve. Here we explore the circumstances that can lead to the creation of these “re-inflated” gas giants and examine how the existence or absence of such planets can be used to place unique constraints on the physics of the hot Jupiter inflation mechanism. Finally, we explore the prospects for detecting this potentially important undiscovered population of planets.

  9. Miniaturized chromatographic radiochemical procedure for 131I - MIBG

    International Nuclear Information System (INIS)

    Barboza, M.F. de; Pereira, N.S. de; Colturato, M.T.; Silva, C.P.G. da.

    1989-12-01

    Different solvents were used in paper chromatographic methods to obtain the best system in routine radiochemical control for 131 I-MIBG produced at IPEN-CNEN/SP. The dates were compared with those obtained with eletrophoresis method in buffer acetate, pH=4.5, 350V, during 40 minutes. The stability of the labeled compound store under 4 0 C was studied during 15 days. Miniaturized chromatographic procedures were established using Whatman 3MM (8x1cm) and n-butanol-:acetic acid: water (S:2:1) as a solvent. the Rf values were: 0.3 (I - ) and 1.0 (MIBG). The radiochemical purity was 99.3 and 99.2% (first day) obtained with eletrophoresis and miniaturized chromatographic procedures, respectively and, 84.7% after 15 days of its preparation. It is a rapid, practical and reproductive method. (author) [pt

  10. Giant duodenal ulcers

    Institute of Scientific and Technical Information of China (English)

    Eric Benjamin Newton; Mark R Versland; Thomas E Sepe

    2008-01-01

    Giant duodenal ulcers (GDUs) are a subset of duodenal ulcers that have historically resulted in greater morbidity than usual duodenal ulcers. Until recently,few cases had been successfully treated with medical therapy. However, the widespread use of endoscopy,the introduction of H-2 receptor blockers and proton pump inhibitors, and the improvement in surgical techniques all have revolutionized the diagnosis,treatment and outcome of this condition. Nevertheless,GDUs are still associated with high rates of morbidity,mortality and complications. Thus, surgical evaluation of a patient with a GDU should remain an integral part of patient care. These giant variants, while usually benign, can frequently harbor malignancy. A careful review of the literature highlights the important differences when comparing GDUs to classical peptic ulcers and why they must be thought of differently than their more common counterpart.

  11. Multifocal tenosynovial giant cell tumors in a child with Noonan syndrome

    Energy Technology Data Exchange (ETDEWEB)

    Meyers, Arthur B. [Children' s Hospital of Wisconsin, Department of Radiology, Milwaukee, WI (United States); Nemours Children' s Health System/Nemours Children' s Hospital, Department of Radiology, Orlando, FL (United States); Awomolo, Agboola O. [Children' s Hospital of Wisconsin, Department of Radiology, Milwaukee, WI (United States); Szabo, Sara [Medical College of Wisconsin and Children' s Hospital of Wisconsin, Department of Pathology, Milwaukee, WI (United States); Cincinnati Children' s Hospital Medical Center, Division of Pathology and Laboratory Medicine, Cincinnati, OH (United States)

    2017-03-15

    Noonan syndrome is a genetic disorder with variable expression of distinctive facial features, webbed neck, chest deformity, short stature, cryptorchidism and congenital heart disease. The association of Noonan syndrome and giant cell granulomas of the mandible is widely reported. However, Noonan syndrome may also be associated with single or multifocal tenosynovial giant cell tumors, also referred to as pigmented villonodular synovitis. We report a child with Noonan syndrome, giant cell granulomas of the mandible and synovial and tenosynovial giant cell tumors involving multiple joints and tendon sheaths who was initially misdiagnosed with juvenile idiopathic arthritis. It is important for radiologists to be aware of the association of Noonan syndrome and multifocal giant cell lesions, which can range from the more commonly described giant cell granulomas of the mandible to isolated or multifocal intra- or extra-articular tenosynovial giant cell tumors or a combination of all of these lesions. (orig.)

  12. Multifocal tenosynovial giant cell tumors in a child with Noonan syndrome.

    Science.gov (United States)

    Meyers, Arthur B; Awomolo, Agboola O; Szabo, Sara

    2017-03-01

    Noonan syndrome is a genetic disorder with variable expression of distinctive facial features, webbed neck, chest deformity, short stature, cryptorchidism and congenital heart disease. The association of Noonan syndrome and giant cell granulomas of the mandible is widely reported. However, Noonan syndrome may also be associated with single or multifocal tenosynovial giant cell tumors, also referred to as pigmented villonodular synovitis. We report a child with Noonan syndrome, giant cell granulomas of the mandible and synovial and tenosynovial giant cell tumors involving multiple joints and tendon sheaths who was initially misdiagnosed with juvenile idiopathic arthritis. It is important for radiologists to be aware of the association of Noonan syndrome and multifocal giant cell lesions, which can range from the more commonly described giant cell granulomas of the mandible to isolated or multifocal intra- or extra-articular tenosynovial giant cell tumors or a combination of all of these lesions.

  13. Multifocal tenosynovial giant cell tumors in a child with Noonan syndrome

    International Nuclear Information System (INIS)

    Meyers, Arthur B.; Awomolo, Agboola O.; Szabo, Sara

    2017-01-01

    Noonan syndrome is a genetic disorder with variable expression of distinctive facial features, webbed neck, chest deformity, short stature, cryptorchidism and congenital heart disease. The association of Noonan syndrome and giant cell granulomas of the mandible is widely reported. However, Noonan syndrome may also be associated with single or multifocal tenosynovial giant cell tumors, also referred to as pigmented villonodular synovitis. We report a child with Noonan syndrome, giant cell granulomas of the mandible and synovial and tenosynovial giant cell tumors involving multiple joints and tendon sheaths who was initially misdiagnosed with juvenile idiopathic arthritis. It is important for radiologists to be aware of the association of Noonan syndrome and multifocal giant cell lesions, which can range from the more commonly described giant cell granulomas of the mandible to isolated or multifocal intra- or extra-articular tenosynovial giant cell tumors or a combination of all of these lesions. (orig.)

  14. Miniaturized and reconfigurable notch antenna based on a BST ferroelectric thin film

    Energy Technology Data Exchange (ETDEWEB)

    Nguyen, Hung Viet [Institut d' Electronique et de Télécommunications de Rennes (IETR), IUT Saint-Brieuc, Université de Rennes 1, 22004 Saint-Brieuc (France); CEA-LETI, Minatec, 17 avenue des Martyrs, 38054 Grenoble Cedex 9 (France); Benzerga, Ratiba, E-mail: ratiba.benzerga@univ-rennes1.fr [Institut d' Electronique et de Télécommunications de Rennes (IETR), IUT Saint-Brieuc, Université de Rennes 1, 22004 Saint-Brieuc (France); Borderon, Caroline [IETR, Université de Nantes, 2 rue de la Houssinière, 44322 Nantes (France); Delaveaud, Christophe [CEA-LETI, Minatec, 17 avenue des Martyrs, 38054 Grenoble Cedex 9 (France); Sharaiha, Ala [Institut d' Electronique et de Télécommunications de Rennes (IETR), IUT Saint-Brieuc, Université de Rennes 1, 22004 Saint-Brieuc (France); Renoud, Raphael [IETR, Université de Nantes, 2 rue de la Houssinière, 44322 Nantes (France); Paven, Claire Le [Institut d' Electronique et de Télécommunications de Rennes (IETR), IUT Saint-Brieuc, Université de Rennes 1, 22004 Saint-Brieuc (France); Pavy, Sabrina; Nadaud, Kevin; Gundel, Hartmut W. [IETR, Université de Nantes, 2 rue de la Houssinière, 44322 Nantes (France)

    2015-07-15

    Highlights: • A miniature and agile antenna based on a BST MIM capacitor is simulated and made. • Mn{sup 2+} doped BST thin films are synthesized by chemical deposition and spin coating. • Permittivity and losses of the BST thin film are respectively 225 and 0.02 at 1 GHz. • A miniaturization rate of 70% is obtained with a MIM capacitance of 3.7 pF. • A frequency tunability of 14.5% and a tunability performance of 0.04 are measured. - Abstract: This work deals with the design, realization and characterization of a miniature and frequency agile antenna based on a ferroelectric Ba{sub 0,80}Sr{sub 0,20}TiO{sub 3} thin film. The notch antenna is loaded with a variable metal/insulator/metal (MIM) capacitor and is achieved by a monolithic method. The MIM capacitance is 3.7 pF, which results in a resonant frequency of 670 MHz compared to 2.25 GHz for the unloaded simulated antenna; the resulting miniaturization rate is 70%. The characterization of the antenna prototype shows a frequency tunable rate of 14.5% under an electric field of 375 kV/cm, with a tunability performance η = 0.04.

  15. Giant Panda habitat selection in the Foping Nature Reserve, China

    NARCIS (Netherlands)

    Liu, X.; Toxopeus, A.G.; Skidmore, A.K.; Shao, X.; Dang, D.; Wang, T.; Prins, H.H.T.

    2005-01-01

    Little is known about habitat selection of the giant panda (Ailuropoda melanoleuca), especially about the relationship between giant panda presence and bamboo and tree structures. We presented data on giant panda habitat use and selection in Foping Nature Reserve (NR), China. We used 1,066

  16. A study on plate anchor detailing systems of shear re-bar

    International Nuclear Information System (INIS)

    Tsurumaki, S.; Ujiie, K.; Nishikawa, T.; Kitayama, K.

    1995-01-01

    For shell walls and base slabs in reactor buildings, besides a large amount of main bars, numerous shear re-bars have been employed to resist to out-of-plane force. As a result , detailing work involving shear re-bar is extremely involved. For example, the employed re-bar anchor method differs from the ordinary methods in which, a end of shear re-bar with 135-degrees hook or with anchor plate type and another re-bar end with 90-degrees hook are used. However the structural characteristics in members using shear re-bar of the bolt-mounted anchor plate have not yet been examined. A test was performed to confirm the effects of anchor methods for shear re-bars on shearing behavior of members. This paper describes the test plan, method and results. (author). 12 figs., 7 tabs

  17. Gamma graphic findings in giant hepatic hemangioma

    International Nuclear Information System (INIS)

    Cano, R.; Morales, R.; Mendoza, P.; Ramirez, E.; Aguilar, C.

    1994-01-01

    The aim of the present work is to describe gamma graphic findings in patients with giant hepatic hemangiomas, when evaluated with 99m Tc red blood cell (RBC) imaging. Three patients with clinical suspicion of giant hepatic hemangiomas, who had had, ultrasound and computed tomography were studied with RBC using in vivo labelling with pyrophosphate. All cases had dynamic and static views. All cases showed hypoperfusion in dynamics views and over perfusion in delayed studies. Surgery confirmed diagnosis in two cases. 99m Tc RBC is a good method for diagnosis of giant hepatic hemangioma, which generally needs surgical treatment. (Authors). 24 refs., 2 figs

  18. Miniature X-ray Tube for Electric Brachytherapy using Carbon Nanotube Field Emitter

    International Nuclear Information System (INIS)

    Heo, Sung Hwan; Kim, Hyun Jin; Ha, Jun Mok; Cho, Sung Oh

    2011-01-01

    An electric brachytherapy using a miniature x-ray tube has a major advantage to reduce the x-ray exposure of human body during the cancer radiation therapy by optimal positioning of x-ray radiation source and treatment objectives. In the view of a smaller electronic x-ray source, the CNT field emitter based xray tube can be more minimized than thermionic filament emitter based one because of a simple power supplier connection of cold field emission in diode type as well as a higher electron emission brightness of CNT. This abstract is for introducing the design of a prototype CNT field emitter based miniature x-ray tube. We have vacuum sealed CNT miniature x-ray tube with 7∼10 mm diameter, and characteristics of electron emission and x-ray transportation using MCNP5 code are surveyed

  19. Totally thrombosed giant anterior communicating artery aneurysm

    Directory of Open Access Journals (Sweden)

    V R Roopesh Kumar

    2015-01-01

    Full Text Available Giant anterior communicating artery aneurysmsarerare. Apatient presented with visual dysfunction, gait ataxia and urinary incontinence. MRI showed a giant suprasellar mass.At surgery, the lesion was identified as being an aneurysm arising from the anterior communicating artery.The difficulty in preoperative diagnosis and relevant literature are reviewed.

  20. A miniaturized plastic dilution refrigerator

    International Nuclear Information System (INIS)

    Bindilatti, V.; Oliveira, N.F.Jr.; Martin, R.V.; Frossati, G.

    1996-01-01

    We have built and tested a miniaturized dilution refrigerator, completely contained (still, heat exchanger and mixing chamber) inside a plastic (PVC) tube of 10 mm diameter and 170 mm length. With a 25 cm 2 CuNi heat exchanger, it reached temperatures below 50 mK, for circulation rates below 70 μmol/s. The cooling power at 100 mK and 63 μmol/s was 45 μW. The experimental space could accommodate samples up to 6 mm in diameter. (author)

  1. New properties of giant resonances in highly excited nuclei

    International Nuclear Information System (INIS)

    Morsch, H.P.

    1991-01-01

    Studies on the giant dipole resonance in very hot nuclei investigated in heavy ion-induced particle-γ coincidence experiments are reviewed. A signature is found in the γ-decay of excited nuceli which shows direct decay of the giant dipole resonance. This provides a new dimension in giant resonance studies and the possibility to study the dependence of giant resonance energy, width and sum rule strength on excitation energy and rotation of the system. Further, the fact that the giant resonance splits in deformed nuclei provides a unique way to get information on the shape of hot nuclei. First results are obtained on the following questions: (i)What is the nuclear shape at high temperature (T≥2 MeV)? (ii)Is there a phase transition in the nuclear shape at T∼1.7 MeV? (iii)Does motional narrowing exist in hot nuclei? (author). 19 refs., 11 figs

  2. A Gas-Poor Planetesimal Feeding Model for the Formation of Giant Planet Satellite Systems: Consequences for the Atmosphere of Titan

    Science.gov (United States)

    Estrada, P. R.; Mosqueira, I.

    2005-01-01

    Given our presently inadequate understanding of the turbulent state of the solar and planetary nebulae, we believe the way to make progress in satellite formation is to consider two end member models that avoid over-reliance on specific choices of the turbulence (alpha), which is essentially a free parameter. The first end member model postulates turbulence decay once giant planet accretion ends. If so, Keplerian disks must eventually pass through the quiescent phases, so that the survival of satellites (and planets) ultimately hinges on gap-opening. In this scenario, the criterion for gap-opening itself sets the value for the gas surface density of the satellite disk.

  3. Statistical decay of giant resonances

    International Nuclear Information System (INIS)

    Dias, H.; Teruya, N.; Wolynec, E.

    1986-01-01

    Statistical calculations to predict the neutron spectrum resulting from the decay of Giant Resonances are discussed. The dependence of the resutls on the optical potential parametrization and on the level density of the residual nucleus is assessed. A Hauser-Feshbach calculation is performed for the decay of the monople giant resonance in 208 Pb using the experimental levels of 207 Pb from a recent compilation. The calculated statistical decay is in excelent agreement with recent experimental data, showing that the decay of this resonance is dominantly statistical, as predicted by continuum RPA calculations. (Author) [pt

  4. Statistical decay of giant resonances

    International Nuclear Information System (INIS)

    Dias, H.; Teruya, N.; Wolynec, E.

    1986-02-01

    Statistical calculations to predict the neutron spectrum resulting from the decay of Giant Resonances are discussed. The dependence of the results on the optical potential parametrization and on the level density of the residual nucleus is assessed. A Hauser-Feshbach calculation is performed for the decay of the monopole giant resonance in 208 Pb using the experimental levels of 207 Pb from a recent compilation. The calculated statistical decay is in excellent agreement with recent experimental data, showing that decay of this resonance is dominantly statistical, as predicted by continuum RPA calculations. (Author) [pt

  5. A molecular diagnostic test for persistent Müllerian duct syndrome in miniature schnauzer dogs.

    Science.gov (United States)

    Pujar, S; Meyers-Wallen, V N

    2009-01-01

    In persistent Müllerian duct syndrome (PMDS), Müllerian ducts fail to regress in males during sexual differentiation. In the canine miniature schnauzer model, PMDS is caused by a C to T transition in exon 3 of the Müllerian inhibiting substance type II receptor (MISRII), which introduces a DdeI restriction site. Here we report a molecular diagnostic test for PMDS in the miniature schnauzer to identify affected dogs and carriers. As our test results suggest that the mutation is identical by descent in affected dogs of this breed, the test could be used to eliminate this mutation from the miniature schnauzer breed worldwide.

  6. Ultra-wideband ladder filters using zero-th shear mode plate wave in ultrathin LiNbO3 plate with apodized interdigital transducers

    Science.gov (United States)

    Kadota, Michio; Tanaka, Shuji

    2016-07-01

    There are two kinds of plate waves propagating in a thin plate, Lamb and shear horizontal (SH) waves. The former has a velocity higher than 15,000 m/s when the plate is very thin. On the contrary, 0th SH (SH0) mode plate wave in an ultrathin LiNbO3 plate has an electro-mechanical coupling factor larger than 50%. Authors fabricated an ultra-wideband T-type ladder filter with a relative bandwidth (BW) of 41% using the SH0 mode plate wave. Although the BW of the filter fully covers the digital TV band in Japan, it does not have sufficient margin at the lower and higher end of BW. Besides, periodic small ripples due to transverse mode in pass-band of the filter were observed. In this study π-type ladder filters were fabricated by changing the pitch ratio of interdigital transducer (IDT) of parallel and series arm resonators (PR(IDT)) to control the BW, and by apodizing IDTs to improve the periodic small ripples due to transverse mode. Ultra-wideband filters without periodic small transverse mode with ultrawide bandwidth from 41 to 49% were fabricated. The BWs fully cover ultrawide digital television bands in Japan and U.S.A. These filters with an ultrawide BW and a steep characteristic show the possibility to be applied to a reported cognitive radio system and other communication systems requiring an ultrawide BW.

  7. Orbital maneuvering end effectors

    Science.gov (United States)

    Myers, W. Neill (Inventor); Forbes, John C. (Inventor); Barnes, Wayne L. (Inventor)

    1986-01-01

    This invention relates to an end effector device for grasping and maneuvering objects such as berthing handles of a space telescope. The device includes a V-shaped capture window defined as inclined surfaces in parallel face plates which converge toward a retainer recess in which the handle is retained. A pivotal finger (30) meshes with a pair of pivoted fingers which rotate in counterrotation. The fingers rotate to pull a handle within the capture window into recess where latches lock handle in the recess. To align the capture window, plates may be cocked plus or minus five degrees on base. Drive means is included in the form of a motor coupled with a harmonic drive speed reducer, which provides for slow movement of the fingers at a high torque so that large articles may be handled. Novelty of the invention is believed to reside in the combined intermeshing finger structure, drive means and the harmonic drive speed reducer, which features provide the required maneuverability and strength.

  8. Maxillary bone epithelial cyst in an adult miniature schnauzer.

    Science.gov (United States)

    Lin, Chung-Tien; Tasi, Wen-Chih; Hu, Chun-Kun; Lin, Nien-Ting; Huang, Pei-Yun; Yeh, Lih-Seng

    2008-09-01

    Maxillary bone epithelial cyst is rare in dogs. A 5-year-old, spayed female miniature schnauzer developed a swelling below the nasal canthus of left eye. Plain radiograph demonstrated a 1.5 cm diameter of radiolucent lesion on the maxillary bone anteroventral to the eye, and contrast dacryocystorhinography confirmed an obstructed nasolarcrimal duct. The swelling showed poor response to antibiotic treatment but responded well to oral prednisolone. Exploratory surgery revealed a cyst-like structure filled with brown serous fluid. Histopathological examination of the removed cyst revealed a double cuboidal epithelial cyst. The dog recovered rapidly after surgery, and the swelling had not recurred for a 36-month follow-up. It is the first case of periorbital bone epithelial cyst reported in an adult miniature schnauzer.

  9. Miniaturizing EM Sample Preparation: Opportunities, Challenges, and "Visual Proteomics".

    Science.gov (United States)

    Arnold, Stefan A; Müller, Shirley A; Schmidli, Claudio; Syntychaki, Anastasia; Rima, Luca; Chami, Mohamed; Stahlberg, Henning; Goldie, Kenneth N; Braun, Thomas

    2018-03-01

    This review compares and discusses conventional versus miniaturized specimen preparation methods for transmission electron microscopy (TEM). The progress brought by direct electron detector cameras, software developments and automation have transformed transmission cryo-electron microscopy (cryo-EM) and made it an invaluable high-resolution structural analysis tool. In contrast, EM specimen preparation has seen very little progress in the last decades and is now one of the main bottlenecks in cryo-EM. Here, we discuss the challenges faced by specimen preparation for single particle EM, highlight current developments, and show the opportunities resulting from the advanced miniaturized and microfluidic sample grid preparation methods described, such as visual proteomics and time-resolved cryo-EM studies. © 2018 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  10. Asteroseismology of 16,000 Kepler Red Giants

    DEFF Research Database (Denmark)

    Yu, Jie; Huber, Daniel; Bedding, Timothy R.

    2018-01-01

    (sigma(M) = 7.8%), radius (sigma(R) = 2.9%), and thus surface gravity (sigma(log g) = 0.01 dex). Thanks to the large red giant sample, we confirm that red-giant-branch (RGB) and helium-core-burning (HeB) stars collectively differ in the distribution of oscillation amplitude, granulation power, and width...

  11. Giant hydronephrosis mimicking progressive malignancy

    Science.gov (United States)

    Schrader, Andres Jan; Anderer, Georgia; von Knobloch, Rolf; Heidenreich, Axel; Hofmann, Rainer

    2003-01-01

    Background Cases of giant hydronephroses are rare and usually contain no more than 1–2 litres of fluid in the collecting system. We report a remarkable case of giant hydronephrosis mimicking a progressive malignant abdominal tumour. Case presentation A 78-year-old cachectic woman presented with an enormous abdominal tumour, which, according to the patient, had slowly increased in diameter. Medical history was unremarkable except for a hysterectomy >30 years before. A CT scan revealed a giant cystic tumour filling almost the entire abdominal cavity. It was analysed by two independent radiologists who suspected a tumour originating from the right kidney and additionally a cystic ovarian neoplasm. Subsequently, a diagnostic and therapeutic laparotomy was performed: the tumour presented as a cystic, 35 × 30 × 25 cm expansive structure adhesive to adjacent organs without definite signs of invasive growth. The right renal hilar vessels could finally be identified at its basis. After extirpation another tumourous structure emerged in the pelvis originating from the genital organs and was also resected. The histopathological examination revealed a >15 kg hydronephrotic right kidney, lacking hardly any residual renal cortex parenchyma. The second specimen was identified as an ovary with regressive changes and a large partially calcified cyst. There was no evidence of malignant growth. Conclusion Although both clinical symptoms and the enormous size of the tumour indicated malignant growth, it turned out to be a giant hydronephrosis. Presumably, a chronic obstruction of the distal ureter had caused this extraordinary hydronephrosis. As demonstrated in our case, an accurate diagnosis of giant hydronephrosis remains challenging due to the atrophy of the renal parenchyma associated with chronic obstruction. Therefore, any abdominal cystic mass even in the absence of other evident pathologies should include the differential diagnosis of a possible hydronephrosis. Diagnostic

  12. Modeling and simulation of flow field in giant magnetostrictive pump

    Science.gov (United States)

    Zhao, Yapeng; Ren, Shiyong; Lu, Quanguo

    2017-09-01

    Recent years, there has been significant research in the design and analysis of giant magnetostrictive pump. In this paper, the flow field model of giant magnetostrictive pump was established and the relationship between pressure loss and working frequency of piston was studied by numerical simulation method. Then, the influence of different pump chamber height on pressure loss in giant magnetostrictive pump was studied by means of flow field simulation. Finally, the fluid pressure and velocity vector distribution in giant magnetostrictive pump chamber were simulated.

  13. Revealing the microstructure of the giant component in random graph ensembles

    Science.gov (United States)

    Tishby, Ido; Biham, Ofer; Katzav, Eytan; Kühn, Reimer

    2018-04-01

    The microstructure of the giant component of the Erdős-Rényi network and other configuration model networks is analyzed using generating function methods. While configuration model networks are uncorrelated, the giant component exhibits a degree distribution which is different from the overall degree distribution of the network and includes degree-degree correlations of all orders. We present exact analytical results for the degree distributions as well as higher-order degree-degree correlations on the giant components of configuration model networks. We show that the degree-degree correlations are essential for the integrity of the giant component, in the sense that the degree distribution alone cannot guarantee that it will consist of a single connected component. To demonstrate the importance and broad applicability of these results, we apply them to the study of the distribution of shortest path lengths on the giant component, percolation on the giant component, and spectra of sparse matrices defined on the giant component. We show that by using the degree distribution on the giant component one obtains high quality results for these properties, which can be further improved by taking the degree-degree correlations into account. This suggests that many existing methods, currently used for the analysis of the whole network, can be adapted in a straightforward fashion to yield results conditioned on the giant component.

  14. Miniaturized protein separation using a liquid chromatography column on a flexible substrate

    International Nuclear Information System (INIS)

    Yang Yongmo; Chae, Junseok

    2008-01-01

    We report a prototype protein separator that successfully miniaturizes existing technology for potential use in biocompatible health monitoring implants. The prototype is a liquid chromatography (LC) column (LC mini-column) fabricated on an inexpensive, flexible, biocompatible polydimethylsiloxane (PDMS) enclosure. The LC mini-column separates a mixture of proteins using size exclusion chromatography (SEC) with polydivinylbenzene beads (5–20 µm in diameter with 10 nm pore size). The LC mini-column is smaller than any commercially available LC column by a factor of ∼11 000 and successfully separates denatured and native protein mixtures at ∼71 psi of the applied fluidic pressure. Separated proteins are analyzed using NuPAGE-gel electrophoresis, high-performance liquid chromatography (HPLC) and an automated electrophoresis system. Quantitative HPLC results demonstrate successful separation based on intensity change: within 12 min, the intensity between large and small protein peaks changed by a factor of ∼20. In further evaluation using the automated electrophoresis system, the plate height of the LC mini-column is between 36 µm and 100 µm. The prototype LC mini-column shows the potential for real-time health monitoring in applications that require inexpensive, flexible implant technology that can function effectively under non-laboratory conditions

  15. Surgical management of giant posterior communicating artery aneurysms.

    Science.gov (United States)

    Velat, Gregory J; Zabramski, Joseph M; Nakaji, Peter; Spetzler, Robert F

    2012-09-01

    Giant posterior communicating artery (PCoA) aneurysms (> 25 mm) are rare lesions associated with a poor prognosis and high rates of morbidity and mortality. To review the clinical results of giant PCoA aneurysms surgically treated at our institution, focusing on operative nuances. All cases of giant PCoA aneurysms treated surgically at our institution were identified from a prospectively maintained patient database. Patient demographic factors, medical comorbidities, rupture status, neurological presentation, clinical outcomes, and surgical records were critically reviewed. From 1989 to 2010, 11 patients (10 women) underwent surgical clipping of giant PCoA aneurysms. Presenting signs and symptoms included cranial nerve palsies, diminished mental status, headache, visual changes, and seizures. Five aneurysms were ruptured on admission. All aneurysms were clipped primarily except 1, which was treated by parent artery sacrifice and extracranial-to-intracranial bypass after intraoperative aneurysm rupture. Perioperative morbidity and mortality rates were 36% (4 of 11) and 18.3% (2 of 11), respectively. Excellent or good clinical outcomes, defined as modified Rankin Scale scores ≤ 2, were achieved in 86% (5 of 6) of patients available for long-term clinical follow-up (mean, 12.5 ± 13.6 months). Giant PCoA aneurysms are rare vascular lesions that may present with a variety of neurological signs and symptoms. These lesions can be successfully managed surgically with satisfactory morbidity and mortality rates. To the best of our knowledge, this is the largest surgical series of giant PCoA aneurysms published to date.

  16. Think big--giant genes in bacteria.

    Science.gov (United States)

    Reva, Oleg; Tümmler, Burkhard

    2008-03-01

    Long genes should be rare in archaea and eubacteria because of the demanding costs of time and resources for protein production. The search in 580 sequenced prokaryotic genomes, however, revealed 0.2% of all genes to be longer than 5 kb (absolute number: 3732 genes). Eighty giant bacterial genes of more than 20 kb in length were identified in 47 taxa that belong to the phyla Thermotogae (1), Chlorobi (3), Planctomycetes (1), Cyanobacteria (2), Firmicutes (7), Actinobacteria (9), Proteobacteria (23) or Euryarchaeota (1) (number of taxa in brackets). Giant genes are strain-specific, differ in their tetranucleotide usage from the bulk genome and occur preferentially in non-pathogenic environmental bacteria. The two longest bacterial genes known to date were detected in the green sulfur bacterium Chlorobium chlorochromatii CaD3 encoding proteins of 36 806 and 20 647 amino acids, being surpassed in length only by the human titin coding sequence. More than 90% of bacterial giant genes either encode a surface protein or a polyketide/non-ribosomal peptide synthetase. Most surface proteins are acidic, threonine-rich, lack cystein and harbour multiple amino acid repeats. Giant proteins increase bacterial fitness by the production of either weapons towards or shields against animate competitors or hostile environments.

  17. Giant viruses of amoebas: an update

    Directory of Open Access Journals (Sweden)

    Sarah eAherfi

    2016-03-01

    Full Text Available During the 12 past years, five new or putative virus families encompassing several members, namely Mimiviridae, Marseilleviridae, pandoraviruses, faustoviruses, and virophages were described. In addition, Pithovirus sibericum and Mollivirus sibericum represent type strains of putative new giant virus families. All these viruses were isolated using amoebal coculture methods. These giant viruses were linked by phylogenomic analyses to other large DNA viruses. They were then proposed to be classified in a new viral order, the Megavirales, on the basis of their common origin, as shown by a set of ancestral genes encoding key viral functions, a common virion architecture, and shared major biological features including replication inside cytoplasmic factories. Megavirales is increasingly demonstrated to stand in the tree of life aside Bacteria, Archaea and Eukarya, and the megavirus ancestor is suspected to be as ancient as cellular ancestors. In addition, giant amoebal viruses are visible under a light microscope and display many phenotypic and genomic features not found in other viruses, while they share other characteristics with parasitic microbes. Moreoever, these organisms appear to be common inhabitants of our biosphere, and mimiviruses and marseilleviruses were isolated from human samples and associated to diseases. In the present review, we describe the main features and recent findings on these giant amoebal viruses and virophages.

  18. Fabrication of miniature magnetic magnet pole for validate simulation of magnetic cyclotron proton 13 MeV

    International Nuclear Information System (INIS)

    Subroto; Sukiya; Tony R

    2013-01-01

    A fabrication of miniature magnetic pole field has been made to validate the simulation system 13 MeV magnet of proton cyclotron using mild steel material. This electromagnet of magnetic pole at the end of the magnetic pole is divided into 8 parts of the valley and the hill interval to produce different magnetic field. Pole magnetic field fabrication is meet to match the design of the system simulation results 13 MeV cyclotron magnet. This requires strong cyclotron magnetic field average at 1.275 T magnetic field strength of each piece was different. So that the ion beam passing through a magnetic field. Will be focused before mashing target. The surface of magnetic pole is circular with a diameter of 100 mm and 32 mm pole spacing. Miniature of electrical pole diameter is only one-tenth the diameter of 960 mm designed this requires current 10 A with voltage 30 V to produce field strength of 0.3 T. To measure the magnetic field strength tesla meter is used and to measure the relationship curve in pole position with a magnetic field strength magnets cylinder directions X and Y the used mini lathe. Field strength measurement results with a straight, oblique and circular position show nearly equal to curve simulation results using a 3D module TOSCA opera program. (author)

  19. Proteinuria and lipoprotein lipase activity in Miniature Schnauzer dogs with and without hypertriglyceridemia.

    Science.gov (United States)

    Furrow, E; Jaeger, J Q; Parker, V J; Hinchcliff, K W; Johnson, S E; Murdoch, S J; de Boer, I H; Sherding, R G; Brunzell, J D

    2016-06-01

    Spontaneous hyperlipidemia in rats causes glomerular disease. Idiopathic hypertriglyceridemia (HTG) is prevalent in Miniature Schnauzers, but its relationship with proteinuria is unknown. Decreased activity of major lipid metabolism enzymes, lipoprotein lipase (LPL) and hepatic lipase (HL), may play a role in the cyclic relationship between hyperlipidemia and proteinuria. These enzymes have also not been previously investigated in Miniature Schnauzers. The aims of this study were to determine the relationship between HTG and proteinuria in Miniature Schnauzers and to measure LPL and HL activities in a subset of dogs. Fifty-seven Miniature Schnauzers were recruited (34 with and 23 without HTG). Fasting serum triglyceride concentrations and urine protein-to-creatinine ratios (UPC) were measured in all dogs, and LPL and HL activities were determined in 17 dogs (8 with and 9 without HTG). There was a strong positive correlation between triglyceride concentration and UPC (r = 0.77-0.83, P Schnauzers and could be due to lipid-induced glomerular injury. Reduced LPL activity may contribute to the severity of HTG, but further assay validation is required. Copyright © 2016 Elsevier Ltd. All rights reserved.

  20. Spatial Memory in Captive Giant Anteaters (Myrmecophaga tridactyla

    Directory of Open Access Journals (Sweden)

    Stephanie M. Allard

    2014-08-01

    Full Text Available The type of learning exhibited during foraging has been studied in a large number of species. Species that feed on food sources that temporally vary in quality could be well suited for exhibiting evidence of spatial learning. The foraging strategies of captive giant anteaters were examined using an experimental foraging task. Two giant anteaters were exposed to a modified radial arm maze in order to determine whether or not they would demonstrate evidence of spatial learning. Both subjects demonstrated significant improvement in performance by visiting baited feeders more consistently across learning trials. A disruption in performance occurred when the task was reversed, indicating that giant anteaters may use spatial learning to locate food sources. Obtaining a more sound understanding of the cognitive abilities of giant anteaters may help to enhance their welfare in captive settings.

  1. Miniature Reaction Wheel for Small Satellite Control, Phase I

    Data.gov (United States)

    National Aeronautics and Space Administration — The overall goal of this project is to design, develop, demonstrate, and deliver a miniature, high torque, low-vibration reaction wheel for use on small satellites....

  2. Miniature, mobile X-ray computed radiography system

    Science.gov (United States)

    Watson, Scott A; Rose, Evan A

    2017-03-07

    A miniature, portable x-ray system may be configured to scan images stored on a phosphor. A flash circuit may be configured to project red light onto a phosphor and receive blue light from the phosphor. A digital monochrome camera may be configured to receive the blue light to capture an article near the phosphor.

  3. Hepatic Giant Cell Arteritis and Polymyalgia Rheumatica

    Directory of Open Access Journals (Sweden)

    Donald R Duerksen

    1994-01-01

    Full Text Available Polymyalgia rheumatica (PMR is a clinical syndrome of the elderly characterized by malaise, proximal muscle aching and stiffness, low grade fever, elevated erythrocyte sedimentation rare and the frequent association with temporal giant cell arteritis. The authors describe a case of PMR associated with hepatic giant cell arteritis. This lesion has been described in two other clinical reports. The distribution of the arteritis may be patchy; in this report, diagnosis was made with a wedge biopsy performed after an initial nonspecific percutaneous liver biopsy. The authors review the spectrum of liver involvement in PMR and giant cell arteritis. Hepatic abnormalities respond to systemic corticosteroids, and patients with hepatic arteritis have a good prognosis.

  4. Giant Interfrontal Encephalocele in an Infant: A Rare Entity.

    Science.gov (United States)

    Faheem, Mohd; Singh, Sunil Kumar; Ojha, Bal Krishna; Chandra, Anil; Srivastava, Chhitij; Jaiswal, Manish; Zeeshan, Qazi

    2016-01-01

    Interfrontal encephalocele is one of the rare varieties of anterior encephalocele, and a giant interfrontal encephalocele is extremely rare. The authors could find only one case report of giant interfrontal encephalocele in the literature. Anterior encephaloceles are more prevalent in South-East Asia and some northern parts of India. Giant encephalocele poses a great challenge to neurosurgeons and neuroanesthetists during surgery, as these infants usually have a low birth weight and a large sac, thus making the infant prone to hypothermia and blood loss among other risks. We encountered a patient with a giant interfrontal encephalocele aged 1 month. The rarity of this case prompted us to this report. © 2016 S. Karger AG, Basel.

  5. The MIT miniaturized disk bend test

    International Nuclear Information System (INIS)

    Harling, O.K.; Lee, M.; Sohn, D.S.; Kohse, G.; Lau, C.W.

    1983-01-01

    A miniaturized disk bend test (MDBT) using transmission electron microscopy specimens for the determination of various mechanical properties is being developed at MIT. Recent progress in obtaining strengths and ductilities of highly irradiated metal alloys is reviewed. Possibilities exist for applying the MDBT approach to the determination of other mechanical properties. Progress in fatigue testing and in determination of the ductile-to-brittle transition temperature is reviewed briefly

  6. Scale-up of Carbon/Carbon Bipolar Plates

    Energy Technology Data Exchange (ETDEWEB)

    David P. Haack

    2009-04-08

    This project was focused upon developing a unique material technology for use in PEM fuel cell bipolar plates. The carbon/carbon composite material developed in this program is uniquely suited for use in fuel cell systems, as it is lightweight, highly conductive and corrosion resistant. The project further focused upon developing the manufacturing methodology to cost-effectively produce this material for use in commercial fuel cell systems. United Technology Fuel Cells Corp., a leading fuel cell developer was a subcontractor to the project was interested in the performance and low-cost potential of the material. The accomplishments of the program included the development and testing of a low-cost, fully molded, net-shape carbon-carbon bipolar plate. The process to cost-effectively manufacture these carbon-carbon bipolar plates was focused on extensively in this program. Key areas for cost-reduction that received attention in this program was net-shape molding of the detailed flow structures according to end-user design. Correlations between feature detail and process parameters were formed so that mold tooling could be accurately designed to meet a variety of flow field dimensions. A cost model was developed that predicted the cost of manufacture for the product in near-term volumes and long-term volumes (10+ million units per year). Because the roduct uses lowcost raw materials in quantities that are less than competitive tech, it was found that the cost of the product in high volume can be less than with other plate echnologies, and can meet the DOE goal of $4/kW for transportation applications. The excellent performance of the all-carbon plate in net shape was verified in fuel cell testing. Performance equivalent to much higher cost, fully machined graphite plates was found.

  7. Spectral Flattening at Low Frequencies in Crab Giant Pulses

    Science.gov (United States)

    Meyers, B. W.; Tremblay, S. E.; Bhat, N. D. R.; Shannon, R. M.; Kirsten, F.; Sokolowski, M.; Tingay, S. J.; Oronsaye, S. I.; Ord, S. M.

    2017-12-01

    We report on simultaneous wideband observations of Crab giant pulses with the Parkes radio telescope and the Murchison Widefield Array (MWA). The observations were conducted simultaneously at 732 and 3100 MHz with Parkes and at 120.96, 165.76, and 210.56 MHz with the MWA. Flux density calibration of the MWA data was accomplished using a novel technique based on tied-array beam simulations. We detected between 90 and 648 giant pulses in the 120.96-210.56 MHz MWA subbands above a 5.5σ threshold, while in the Parkes subbands we detected 6344 and 231 giant pulses above a threshold of 6σ at 732 and 3100 MHz, respectively. We show, for the first time over a wide frequency range, that the average spectrum of Crab giant pulses exhibits a significant flattening at low frequencies. The spectral index, α, for giant pulses evolves from a steep, narrow distribution with a mean α =-2.6 and width {σ }α =0.5 between 732 and 3100 MHz to a wide, flat distribution of spectral indices with a mean α =-0.7 and width {σ }α =1.4 between 120.96 and 165.76 MHz. We also comment on the plausibility of giant pulse models for fast radio bursts based on this spectral information.

  8. Miniature magnetic fluid seal working in liquid environments

    Science.gov (United States)

    Mitamura, Yoshinori; Durst, Christopher A.

    2017-06-01

    This study was carried out to develop a miniature magnetic fluid (MF) seal working in a liquid environment. The miniature MF seal is intended for use in a catheter blood pump. The requirements for the MF seal included a size of less than Ø4×4.5 mm, shaft diameter of 1 mm, sealing pressure of 200 mmHg, shaft speed of up to 40000 rpm, and life of one month. The miniature MF seal was composed of an NdFeB magnet (Ø4×Ø2×1) sandwiched between two pole pieces (Ø4×Ø1.1×0.5). A shield (Ø4×Ø1.2×1.5) was placed on the pole piece facing the liquid to minimize the influence of pump flow on the MF. The seal was installed on a Ø1 shaft. A seal was formed by injecting MF (Ms: 47.8 kA/m and η: 0.5 Pa·sec) into the gap between the pole pieces and the shaft. Total volume of the MF seal was 44 μL. A sealing pressure of 370 mmHg was obtained at motor speeds of 0-40,000 rpm. The seal remained perfect for 10 days in saline under the condition of a pump flow of 1.5 L/min (The test was terminated in accordance with plans). The seal remained intact after ethylene oxide sterilization during which the seal was exposed to high pressures. In conclusion, the newly developed MF seal will be useful for a catheter pump.

  9. Semimicroscopic description of the giant quadrupole resonances in deformed nuclei

    International Nuclear Information System (INIS)

    Kurchev, G.; Malov, L.A.; Nesterenko, V.O.; Soloviev, V.G.

    1976-01-01

    The calculation results of the giant quadrupole isoscalar and isovector resonances performed within the random phase approximation are represented. The strength functions for E2-transitions are calculated for doubly even deformed nuclei in the regions 150 (<=) A < 190 and 228 (<=) A < 248 in the energy interval (0-40) MeV. The following integral characteristics of giant quadrupole resonances are obtained: the position, widths, the contribution to the energy weighted sum rule and the contribution to the total cross section of photoabsorption. The calculations have shown that giant quadrupole resonances are common for all the considered nuclei. The calculated characteristics of the isoscalar giant quadrupole resonance agree with the available experimental data. The calculations also show that the semimicroscopic theory can be successfully applied for the description of giant multipole resonances

  10. Management of giant paraesophageal hernia.

    Science.gov (United States)

    Awais, O; Luketich, J D

    2009-04-01

    Management of giant paraesophageal hernia remains one of the most difficult challenges faced by surgeons treating complex benign esophageal disorders. These large hernias are acquired disorders; therefore, they invariably present in elderly patients. The dilemma that surgeons faced in the open surgical era was the risk of open surgery in this elderly, sick patient population versus the life threatening catastrophic complications, nearly 30% in some series, observed with medical management. During the 1990s, it was clearly recognized that laparoscopic surgery led to decreased morbidity with a quicker recovery. This has lead to a 6-fold increase in the surgical management of giant paraesophageal hernias over the last decade compared to a period of five decades of open surgery; however, this has not necessarily translated into better outcomes. One of the major issues with giant paraesophageal hernias is recognizing short esophagus and performing a lengthening procedure, if needed. Open series which report liberal use of Collis gastroplasty leading to a tension-free intraabdominal fundoplication have shown the best anatomic and clinical outcomes. As we duplicate the open experience laparoscopically, the principle of identifying a shortened esophagus and constructing a neo-esophagus must be honored for the success of the operation. The benefits of laparoscopy are obvious but should not come at the cost of a lesser operation. This review will illustrate that laparoscopic repair of giant paraesophageal hernia at experienced centers can be performed safely with similar outcomes to open series when the fundamental principles of the operation are maintained.

  11. The history, development and application of a uniformly applied load wide plate testing machine

    International Nuclear Information System (INIS)

    Quirk, A.; Bevitt, E.

    1989-01-01

    The paper describes early attempts to use a rigid end wide plate testing machine to investigate the behaviour of centre cracked flat plates. Confusing and inconsistent results arising from the above tests lead to a detailed investigation of the loading characteristics of rigid end machines in general and the difficulties which can arise in the interpretation of data obtained by the use of such machines. In order to overcome the above difficulties which stem largely from uneven load distribution, a versatile testing machine was designed which by use of cheap and easily obtainable components allows the application of a uniformly distributed applied load to a centre cracked test plate. The machine which was commissioned in its original form in 1975 was initially capable of testing plate of 820 mm width and 25 or 48 mm thickness up to maximum stress levels of 488 or 254 MPa respectively. The ease of adaptability of the machine has since permitted its capacity to be increased to handle plate up to 2032 mm wide and 76 mm thickness and by use of double-banked hydraulic jacks stress levels up to 350 MPa can be achieved on plate of these dimensions. The configuration of the machine allows adequate access for strain gauging, crack tip observation and measurements, and temperature control, tests having been conducted in the temperature range -40 0 C to 290 0 C. Advantages and potential for further development of the machine are given together with details of two of a number of fracture studies which have been conducted since its commissioning. (orig.)

  12. Pinching evidences in a miniature plasma focus with fast pseudospark switch

    International Nuclear Information System (INIS)

    Hassan, S M; Zhang, T; Patran, A; Rawat, R S; Springham, S V; Tan, T L; Wong, D; Wang, W; Lee, S; Gribkov, V A; Mohanty, S R; Lee, P

    2006-01-01

    We report the observations of pinching in a miniature plasma focus (PF) (58-160 J) operated in repetitive mode using fast pseudospark switch (PSS). The size of the device, which includes the capacitor bank, PSS and the focus chamber, is of the order of 22 cm x 22 cm x 38 cm. Several diagnostic tools, the gated imager, streak camera, current and voltage probe, are employed simultaneously to confirm the occurrence of pinching in this fast miniature PF device. The device is optimized for operation in neon and hydrogen as the working gas. The best focus formation was obtained at pressures between 0.5 to 8.0 mbar for neon and between 7.0 to 15.0 mbar for hydrogen. When the system was operated at 100 J with hydrogen as the filling gas, the typical dip in the current derivative signal and the typical peak in the voltage signal associated with pinch compression, are observed to be most intense indicating efficient pinching in the miniature PF device

  13. Current applications of miniaturized chromatographic and electrophoretic techniques in drug analysis.

    Science.gov (United States)

    Aturki, Zeineb; Rocco, Anna; Rocchi, Silvia; Fanali, Salvatore

    2014-12-01

    In the last decade, miniaturized separation techniques have become greatly popular in pharmaceutical analysis. Miniaturized separation methods are increasingly utilized in all processes of drug discovery as well as quality control of pharmaceutical preparation. The great advantages presented by the analytical miniaturized techniques, including high separation efficiency and resolution, rapid analysis and minimal consumption of reagents and samples, make them an attractive alternative to the conventional chromatographic methods for drug analysis. The purpose of this review is to give a general overview of the applicability of capillary electrophoresis (CE), capillary electrochromatography (CEC) and micro/capillary/nano-liquid chromatography (micro-LC/CLC/nano-LC) for the analysis of pharmaceutical formulations, active pharmaceutical ingredients (API), drug impurity testing, chiral drug separation, determination of drugs and metabolites in biological fluids. The results concerning the use of CEC, micro-LC, CLC, and nano-LC in the period 2009-2013, while for CE, those from 2012 up to the review draft are here summarized and some specific examples are discussed. Copyright © 2014 Elsevier B.V. All rights reserved.

  14. The minimum area requirements (MAR) for giant panda: an empirical study.

    Science.gov (United States)

    Qing, Jing; Yang, Zhisong; He, Ke; Zhang, Zejun; Gu, Xiaodong; Yang, Xuyu; Zhang, Wen; Yang, Biao; Qi, Dunwu; Dai, Qiang

    2016-12-08

    Habitat fragmentation can reduce population viability, especially for area-sensitive species. The Minimum Area Requirements (MAR) of a population is the area required for the population's long-term persistence. In this study, the response of occupancy probability of giant pandas against habitat patch size was studied in five of the six mountain ranges inhabited by giant panda, which cover over 78% of the global distribution of giant panda habitat. The probability of giant panda occurrence was positively associated with habitat patch area, and the observed increase in occupancy probability with patch size was higher than that due to passive sampling alone. These results suggest that the giant panda is an area-sensitive species. The MAR for giant panda was estimated to be 114.7 km 2 based on analysis of its occupancy probability. Giant panda habitats appear more fragmented in the three southern mountain ranges, while they are large and more continuous in the other two. Establishing corridors among habitat patches can mitigate habitat fragmentation, but expanding habitat patch sizes is necessary in mountain ranges where fragmentation is most intensive.

  15. A Miniature Data Repository on a Raspberry Pi

    NARCIS (Netherlands)

    Samourkasidis, Argyrios; Athanasiadis, Ioannis N.

    2017-01-01

    This work demonstrates a low-cost, miniature data repository proof-of-concept. Such a system needs to be resilient to power and network failures, and expose adequate processing power for persistent, long-term storage. Additional services are required for interoperable data sharing and visualization.

  16. Lightweight, Miniature Inertial Measurement System

    Science.gov (United States)

    Tang, Liang; Crassidis, Agamemnon

    2012-01-01

    A miniature, lighter-weight, and highly accurate inertial navigation system (INS) is coupled with GPS receivers to provide stable and highly accurate positioning, attitude, and inertial measurements while being subjected to highly dynamic maneuvers. In contrast to conventional methods that use extensive, groundbased, real-time tracking and control units that are expensive, large, and require excessive amounts of power to operate, this method focuses on the development of an estimator that makes use of a low-cost, miniature accelerometer array fused with traditional measurement systems and GPS. Through the use of a position tracking estimation algorithm, onboard accelerometers are numerically integrated and transformed using attitude information to obtain an estimate of position in the inertial frame. Position and velocity estimates are subject to drift due to accelerometer sensor bias and high vibration over time, and so require the integration with GPS information using a Kalman filter to provide highly accurate and reliable inertial tracking estimations. The method implemented here uses the local gravitational field vector. Upon determining the location of the local gravitational field vector relative to two consecutive sensors, the orientation of the device may then be estimated, and the attitude determined. Improved attitude estimates further enhance the inertial position estimates. The device can be powered either by batteries, or by the power source onboard its target platforms. A DB9 port provides the I/O to external systems, and the device is designed to be mounted in a waterproof case for all-weather conditions.

  17. Giant first-forbidden resonances

    International Nuclear Information System (INIS)

    Krmpotic, F.; Nakayama, K.; Sao Paulo Univ.; Pio Galeao, A.; Sao Paulo Univ.

    1983-01-01

    Recent experimental data on first-forbidden charge-exchange resonances are discussed in the framework of a schematic model. We also evaluate the screening of the weak coupling constants induced by both the giant resonances and the δ-isobar. It is shown that the last effect does not depend on the multipolarity of the one-particle moment. Due to the same reason, the fraction of the reaction strength pushed up into the δ-resonance region is always the same regardless of the quantum numbers carried by the excitation. Simple expressions are derived for the dependence of the excitation energies of the first-forbidden giant resonances on the mass number and isospin of the target. The model reproduces consistently both the Gamow-Teller and the first-forbidden resonances. (orig.)

  18. Giant resonances: reaction theory approach

    International Nuclear Information System (INIS)

    Toledo Piza, A.F.R. de; Foglia, G.A.

    1989-09-01

    The study of giant resonances through the use of reaction theory approach is presented and discussed. Measurements of cross-sections to the many available decay channels following excitation of giant multipole resonances (GMR) led one to view these phenomena as complicated dynamical syndromes so that theoretical requirements for their study must be extended beyond the traditional bounds of nuclear structure models. The spectra of decay products following GMR excitation in heavy nuclei are well described by statistical model (Hauser-Feshback, HF) predictions indicated that spreading of the collective modes plays a major role in shaping exclusive cross-sections. (A.C.A.S.) [pt

  19. Migration of accreting giant planets

    Science.gov (United States)

    Robert, C.; Crida, A.; Lega, E.; Méheut, H.

    2017-09-01

    Giant planets forming in protoplanetary disks migrate relative to their host star. By repelling the gas in their vicinity, they form gaps in the disk's structure. If they are effectively locked in their gap, it follows that their migration rate is governed by the accretion of the disk itself onto the star, in a so-called type II fashion. Recent results showed however that a locking mechanism was still lacking, and was required to understand how giant planets may survive their disk. We propose that planetary accretion may play this part, and help reach this slow migration regime.

  20. On the material properties of shell plate formed by line heating

    Directory of Open Access Journals (Sweden)

    Hyung Kyun Lim

    2017-01-01

    Full Text Available This paper is concerned with investigating the plastic material properties of steel plate formed by line heating method, and is aimed at implementing more rational design considering the accidental limit states such as collision or grounding. For the present study, line heating test for marine grade steel plate has been carried out with varying plate thickness and heating speed, and then microscopic examination and tensile test have been carried out. From the microscopic, it is found that the grain refined zones like ferrite and pearlite are formed all around the heat affected zone. From the tensile test results, it is seen that yield strength, tensile strength, fracture strain, hardening exponent and strength coefficient vary with plate thickness and heat input quantity. The formulae relating the material properties and heat input parameter should be, therefore, derived for the design purpose considering the accidental impact loading. This paper ends with describing the extension of the present study.