Screening specifications for Gulf Coast salt domes

International Nuclear Information System (INIS)

Brunton, G.D.; Laughon, R.B.; McClain, W.C.

1978-01-01

A reconnaissance survey of the salt domes of Mississippi, Louisiana, and east Texas is being planned to identify study areas for potential sites for radioactive waste disposal. Preliminary screening specifications were derived for each of the geological evaluation criteria by application of the significant factors that will have an impact on the reconnaissance survey. The procedure for the derivation of each screening specification is discussed. The screening specifications are the official OWI values to be used for the first-cut acceptance for salt dome study areas along the Gulf Coast. The derivation of the screening specifications is illustrated by (1) a statement of the geological evaluation criterion, (2) a discussion of the pertinent factors affecting the criterion, and (3) the evaluation of the value of the specification

NWTS program criteria for mined geologic disposal of nuclear waste: functional requirements and performance criteria for waste packages for solidified high-level waste and spent fuel

International Nuclear Information System (INIS)

1982-07-01

The Department of Energy (DOE) has primary federal responsibility for the development and implementation of safe and environmentally acceptable nuclear waste disposal methods. Currently, the principal emphasis in the program is on emplacement of nuclear wastes in mined geologic repositories well beneath the earth's surface. A brief description of the mined geologic disposal system is provided. The National Waste Terminal Storage (NWTS) program was established under DOE's predecessor, the Energy Research and Development Administration, to provide facilities for the mined geologic disposal of radioactive wastes. The NWTS program includes both the development and the implementation of the technology necessary for designing, constructing, licensing, and operating repositories. The program does not include the management of processing radioactive wastes or of transporting the wastes to repositories. The NWTS-33 series, of which this document is a part, provides guidance for the NWTS program in the development and implementation of licensed mined geologic disposal systems for solidified high-level and transuranic (TRU) wastes. This document presents the functional requirements and performance criteria for waste packages for solidified high-level waste and spent fuel. A separate document to be developed, NWTS-33(4b), will present the requirements and criteria for waste packages for TRU wastes. The hierarchy and application of these requirements and criteria are discussed in Section 2.2

Development of a comprehensive list of criteria for evaluating consumer education materials on colorectal cancer screening.

Science.gov (United States)

Dreier, Maren; Borutta, Birgit; Seidel, Gabriele; Kreusel, Inga; Töppich, Jürgen; Bitzer, Eva M; Dierks, Marie-Luise; Walter, Ulla

2013-09-13

Appropriate patient information materials may support the consumer's decision to attend or not to attend colorectal cancer (CRC) screening tests (fecal occult blood test and screening colonoscopy). The aim of this study was to develop a list of criteria to assess whether written health information materials on CRC screening provide balanced, unbiased, quantified, understandable, and evidence-based health information (EBHI) about CRC and CRC screening. The list of criteria was developed based on recommendations and assessment tools for health information in the following steps: (1) Systematic literature search in 13 electronic databases (search period: 2000-2010) and completed by an Internet search (2) Extraction of identified criteria (3) Grouping of criteria into categories and domains (4) Compilation of a manual of adequate answers derived from systematic reviews and S3 guidelines (5) Review by external experts (6) Modification (7) Final discussion with external experts. Thirty-one publications on health information tools and recommendations were identified. The final list of criteria includes a total of 230 single criteria in three generic domains (formal issues, presentation and understandability, and neutrality and balance) and one CRC-specific domain. A multi-dimensional rating approach was used whenever appropriate (e.g., rating for the presence, correctness, presentation and level of evidence of information). Free text input was allowed to ensure the transparency of assessment. The answer manual proved to be essential to the rating process. Quantitative analyses can be made depending on the level and dimensions of criteria. This comprehensive list of criteria clearly has a wider range of evaluation than previous assessment tools. It is not intended as a final quality assessment tool, but as a first step toward thorough evaluation of specific information materials for their adherence to EBHI requirements. This criteria list may also be used to revise

Evidence-based medical research on diagnostic criteria and screening technique of vascular mild cognitive impairment

Directory of Open Access Journals (Sweden)

Xia-wei LIU

2015-07-01

Full Text Available Background Vascular mild cognitive impairment (VaMCI is the prodromal syndrome of vascular dementia (VaD and key target for drug treatment. There is controversy over the diagnostic criteria and screening tools of VaMCI, which affects its clinical diagnosis. This paper aims to explore the clinical features, diagnostic criteria and screening technique of VaMCI.  Methods Taking "vascular mild cognitive impairment OR vascular cognitive impairment no dementia" as retrieval terms, search in PubMed database from January 1997 to March 2015 and screen relevant literatures concerning VaMCI. According to Guidance for the Preparation of Neurological Management Guidelines revised by European Federation of Neurological Societies (EFNS in 2004, evidence grading was performed on literatures. Results A total of 32 literatures in English were selected according to inclusion and exclusion criteria, including 3 guidelines and consensus and 29 clinical studies. Seven literatures (2 on Level Ⅰ, 5 on Level Ⅱ studied on neuropsychological features in VaMCI patients and found reduced processing speed and executive function impairment were main features. Two literatures reported the diagnostic criteria of VaMCI, including VaMCI criteria published by American Heart Association (AHA/American Stroke Association (ASA in 2011 and "Diagnostic Criteria for Vascular Cognitive Disorders" published by International Society for Vascular Behavioral and Cognitive Disorders (VASCOG in 2014. Fifteen literatures (4 on LevelⅠ, 11 on Level Ⅱ described the diagnostic criteria of VaMCI used in clinical research, from which 6 operational diagnostic items were extracted. Fourteen literatures (4 on Level Ⅰ, 10 on Level Ⅱ described neuropsychological assessment tools for VaMCI screening, and found the 5-minute protocol recommended by National Institute of Neurological Disorders and Stroke-Canadian Stroke Network (NINDS-CSN was being good consistency with other neuropsychological

Clinical relevance of the proposed sexual addiction diagnostic criteria: relation to the Sexual Addiction Screening Test-Revised.

Science.gov (United States)

Carnes, Patrick J; Hopkins, Tiffany A; Green, Bradley A

2014-01-01

The present article examines and compares the various diagnostic rubrics proposed to codify symptoms of sexual addiction, and then briefly summarizes the ongoing controversy on whether sexual addiction is a valid construct. Using the diagnostic criteria proposed by , the prevalence rate of each criterion is examined in terms of scores on the Sexual Addiction Screening Test-Revised scales (). Differences in diagnostic criteria endorsement associated with sex, sexual orientation, and setting were also explored. Results from a clinical sample of men and women seeking treatment for sexual addiction demonstrated clinical relevance of the criteria, in that all but 3 criteria are endorsed at more than 50% of participants screening positive for sexual addiction on the Sexual Addiction Screening Test-Revised. Sex differences were also noted for endorsement rates of several of the criteria. Finally, several proposed criteria may pose a higher clinical threshold and thus be utilized by clinicians to identify patients with increased pathology. Results are discussed in the context of existing diagnostic frameworks across etiological perspectives.

A Prospective Study of the Incidence of Retinopathy of Prematurity in China: Evaluation of Different Screening Criteria

Directory of Open Access Journals (Sweden)

Qiuping Li

2016-01-01

Full Text Available To investigate the incidence of Retinopathy of Prematurity (ROP in Beijing, North China, and to evaluate the effectiveness of different ROP screening criteria, we conducted a prospective cohort study in a single-neonatal intensive care unit (NICU. A total of 2997 premature infants with birth weight (BW ≤ 2000 g and/or gestational age (GA ≤ 34 weeks had completed ROP screening. ROP was diagnosed in 356 (11.9% infants. The mean GA was 30.46 ± 1.98 weeks and the mean BW was 1477.35 ± 371.29 g. Of the 59 (2.0% infants receiving treatment, the mean GA was 29.37 ± 2.10 weeks, and the mean BW was 1240.80 ± 330.71 g. The incidence of ROP declined from 14.7% in 2009 and 11.1% in 2010 to 9.5% in 2011. The United Kingdom (UK criteria could reduce the screening number by 40.8%, and 3 infants with type I ROP needing treatment were missed, but none in 2011. The United States (US criteria could reduce the screening number by 66.5%, and 10 infants with type I ROP needing treatment were missed, including one in 2011. So the UK criteria may be appropriate for screening of ROP in our NICU in 2011. Future multisite epidemiologic studies are required to establish suitable ROP screening criteria in China.

Cost Implications of Using Different ECG Criteria for Screening Young Athletes in the United Kingdom.

Science.gov (United States)

Dhutia, Harshil; Malhotra, Aneil; Gabus, Vincent; Merghani, Ahmed; Finocchiaro, Gherardo; Millar, Lynne; Narain, Rajay; Papadakis, Michael; Naci, Huseyin; Tome, Maite; Sharma, Sanjay

2016-08-16

High false-positive rates and cost of additional investigations are an obstacle to electrocardiographic (ECG) screening of young athletes for cardiac disease. However, ECG screening costs have never been systematically assessed in a large cohort of athletes. This study investigated the costs of ECG screening in athletes according to the 2010 European Society of Cardiology (ESC) recommendations and the Seattle and refined interpretation criteria. Between 2011 and 2014, 4,925 previously unscreened athletes aged 14 to 35 years were prospectively evaluated with history, physical examination, and ECG (interpreted with the 2010 ESC recommendations). Athletes with abnormal results underwent secondary investigations, the costs of which were based on U.K. National Health Service Tariffs. The impact on cost after applying the Seattle and refined criteria was evaluated retrospectively. Overall, 1,072 (21.8%) athletes had an abnormal ECG on the basis of 2010 ESC recommendations; 11.2% required echocardiography, 1.7% exercise stress test, 1.2% Holter, 1.2% cardiac magnetic resonance imaging, and 0.4% other tests. The Seattle and refined criteria reduced the number of positive ECGs to 6.0% and 4.3%, respectively. Fifteen (0.3%) athletes were diagnosed with potentially serious cardiac disease using all 3 criteria. The overall cost of de novo screening using 2010 ESC recommendations was $539,888 ($110 per athlete and $35,993 per serious diagnosis). The Seattle and refined criteria reduced the cost to $92 and $87 per athlete screened and $30,251 and $28,510 per serious diagnosis, respectively. Contemporary ECG interpretation criteria decrease costs for de novo screening of athletes, which may be cost permissive for some sporting organizations. Copyright © 2016 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved.

Seismic evaluation of piping systems using screening criteria

International Nuclear Information System (INIS)

Campbell, R.D.; Landers, D.F.; Minichiello, J.C.; Slagis, G.C.; Antaki, G.A.

1994-01-01

This document may be used by a qualified review team to identify potential sources of seismically induced failure in a piping system. Failure refers to the inability of a piping system to perform its expected function following an earthquake, as defined in Table 1. The screens may be used alone or with the Seismic Qualification Utility Group -- Generic Implementation Procedure (SQUG-GIP), depending on the piping system's required function, listed in Table 1. Features of a piping system which do not the screening criteria are called outliers. Outliers must either be resolved through further evaluations, or be considered a potential source of seismically induced failure. Outlier evaluations, which do not necessarily require the qualification of a complete piping system by stress analysis, may be based on one or more of the following: simple calculations of pipe spans, search of the test or experience data, vendor data, industry practice, etc

NRC regulations for disposal of high-level radioactive wastes in geologic repositories: technical criteria

International Nuclear Information System (INIS)

Martin, J.B.; Bell, M.J.; Regnier, E.P.

1983-01-01

The Nuclear Regulatory Commission is promulgating regulations specifying the technical criteria fo disposal of high-level radioactive wastes in geologic repositories. The proposed rule was published for public comment in July 1981. Public comments have been received and considered by the Commission staff. The Commission will soon approve and publish a revised final rule. While the final rule being considered by the Commission is fundamentally the same as the proposed rule, provisions have been added to permit flexibility in the application of numerical criteria, some detailed design requirements have been deleted, and other changes have been made in response to comments. The rule is consistent with the recently enacted Nuclear Waste Policy Act of 1982

Use of DOE site selection criteria for screening low-level waste disposal sites on the Oak Ridge Reservation

International Nuclear Information System (INIS)

Lee, D.W.; Ketelle, R.H.; Stinton, L.H.

1983-09-01

The proposed Department of Energy (DOE) site selection criteria were applied to the Oak Ridge Reservation, and the application was evaluated to determine the criteria's usefulness in the selection of a low-level waste disposal site. The application of the criteria required the development of a methodology to provide a framework for evaluation. The methodology is composed of site screening and site characterization stages. The site screening stage relies on reconnaissance data to identify a preferred site capable of satisfying the site selection criteria. The site characterization stage relies on a detailed site investigation to determine site acceptability. The site selection criteria were applied to the DOE Oak Ridge Reservation through the site screening stage. Results of this application were similar to those of a previous siting study on the Oak Ridge Reservation. The DOE site selection criteria when coupled with the methodology that was developed were easily applied and would be adaptable to any region of interest

Japan's Siting Process for the Geological Disposal of High-level Radioactive Waste - An International Peer Review

International Nuclear Information System (INIS)

Brassinnes, Stephane; Fabbri, Olivier; Rubenstone, James; Seppaelae, Timo; Siemann, Michael; ); Kwong, Gloria; )

2016-01-01

The Nuclear Energy Agency carried out an independent peer review of Japan's siting process and criteria for the geological disposal of high-level radioactive waste in May 2016. The review concluded that Japan's site screening process is generally in accordance with international practices. As the goal of the siting process is to locate a site - that is both appropriate and accepted by the community - to host a geological disposal facility for high-level radioactive waste, the international review team emphasises in this report the importance of maintaining an open dialogue and interaction between the regulator, the implementer and the public. Dialogue should begin in the early phases and continue throughout the siting process. The international review team also underlines the importance of taking into account feasibility aspects when selecting a site for preliminary investigations, but suggests that it would be inappropriate to set detailed scientific criteria for nationwide screening at this stage. The team has provided extensive advisory remarks in the report as opportunities for improvement, including the recommendation to use clear and consistent terminology in defining the site screening criteria as it is a critical factor in a successful siting process. (authors)

ACR Appropriateness Criteria® Breast Cancer Screening.

Science.gov (United States)

Mainiero, Martha B; Moy, Linda; Baron, Paul; Didwania, Aarati D; diFlorio, Roberta M; Green, Edward D; Heller, Samantha L; Holbrook, Anna I; Lee, Su-Ju; Lewin, Alana A; Lourenco, Ana P; Nance, Kara J; Niell, Bethany L; Slanetz, Priscilla J; Stuckey, Ashley R; Vincoff, Nina S; Weinstein, Susan P; Yepes, Monica M; Newell, Mary S

2017-11-01

Breast cancer screening recommendations are based on risk factors. For average-risk women, screening mammography and/or digital breast tomosynthesis is recommended beginning at age 40. Ultrasound (US) may be useful as an adjunct to mammography for incremental cancer detection in women with dense breasts, but the balance between increased cancer detection and the increased risk of a false-positive examination should be considered in the decision. For intermediate-risk women, US or MRI may be indicated as an adjunct to mammography depending upon specific risk factors. For women at high risk due to prior mantle radiation between the ages of 10 to 30, mammography is recommended starting 8 years after radiation therapy but not before age 25. For women with a genetic predisposition, annual screening mammography is recommended beginning 10 years earlier than the affected relative at the time of diagnosis but not before age 30. Annual screening MRI is recommended in high-risk women as an adjunct to mammography. The American College of Radiology Appropriateness Criteria are evidence-based guidelines for specific clinical conditions that are reviewed annually by a multidisciplinary expert panel. The guideline development and revision include an extensive analysis of current medical literature from peer reviewed journals and the application of well-established methodologies (RAND/UCLA Appropriateness Method and Grading of Recommendations Assessment, Development, and Evaluation or GRADE) to rate the appropriateness of imaging and treatment procedures for specific clinical scenarios. In those instances where evidence is lacking or equivocal, expert opinion may supplement the available evidence to recommend imaging or treatment. Copyright © 2017 American College of Radiology. Published by Elsevier Inc. All rights reserved.

Screening for iron deficiency and iron deficiency anaemia in pregnancy: a structured review and gap analysis against UK national screening criteria.

Science.gov (United States)

Rukuni, Ruramayi; Knight, Marian; Murphy, Michael F; Roberts, David; Stanworth, Simon J

2015-10-20

Iron deficiency anaemia is a common problem in pregnancy despite national recommendations and guidelines for treatment. The aim of this study was to appraise the evidence against the UK National Screening Committee (UKNSC) criteria as to whether a national screening programme could reduce the prevalence of iron deficiency anaemia and/or iron deficiency in pregnancy and improve maternal and fetal outcomes. Search strategies were developed for the Cochrane library, Medline and Embase to identify evidence relevant to UK National Screening Committee (UKNSC) appraisal criteria which cover the natural history of iron deficiency and iron deficiency anaemia, the tests for screening, clinical management and evidence of cost effectiveness. Many studies evaluated haematological outcomes of anaemia, but few analysed clinical consequences. Haemoglobin and ferritin appeared the most suitable screening tests, although future options may follow recent advances in understanding iron homeostasis. The clinical consequences of iron deficiency without anaemia are unknown. Oral and intravenous iron are effective in improving haemoglobin and iron parameters. There have been no trials or economic evaluations of a national screening programme for iron deficiency anaemia in pregnancy. Iron deficiency in pregnancy remains an important problem although effective tests and treatment exist. A national screening programme could be of value for early detection and intervention. However, high quality studies are required to confirm whether this would reduce maternal and infant morbidity and be cost effective.

Geological Storage of CO2. Site Selection Criteria; Almacenamiento Geologico de CO2. Criterios de Seleccion de Emplazamientos

Energy Technology Data Exchange (ETDEWEB)

Ruiz, C; Martinez, R; Recreo, F; Prado, P; Campos, R; Pelayo, M; Losa, A de la; Hurtado, A; Lomba, L; Perez del Villar, L; Ortiz, G; Sastre, J

2006-07-01

In year 2002 the Spanish Parliament unanimously passed the ratification of the Kyoto Protocol, signed December 1997, compromising to limiting the greenhouse gas emissions increase. Later on, the Environment Ministry submitted the Spanish National Assignment Emissions Plan to the European Union and in year 2005 the Spanish Greenhouse Gas market started working, establishing taxes to pay in case of exceeding the assigned emissions limits. So, the avoided emissions of CO2 have now an economic value that is promoting new anthropogenic CO2 emissions reduction technologies. Carbon Capture and Storage (CCS) are among these new technological developments for mitigating or eliminate climate change. CO2 can be stored in geological formations such as depleted oil or gas fields, deep permeable saline water saturated formations and unmineable coal seams, among others. This report seeks to establish the selection criteria for suitable geological formations for CO2 storage in the Spanish national territory, paying attention to both the operational and performance requirements of these storage systems. The report presents the physical and chemical properties and performance of CO2 under storage conditions, the transport and reaction processes of both supercritical and gaseous CO2, and CO2 trapping mechanisms in geological formations. The main part of the report is devoted to geological criteria at watershed, site and formation scales. (Author) 100 ref.

ACR Appropriateness Criteria® Ovarian Cancer Screening.

Science.gov (United States)

Pandharipande, Pari V; Lowry, Kathryn P; Reinhold, Caroline; Atri, Mostafa; Benson, Carol B; Bhosale, Priyadarshani R; Green, Edward D; Kang, Stella K; Lakhman, Yulia; Maturen, Katherine E; Nicola, Refky; Salazar, Gloria M; Shipp, Thomas D; Simpson, Lynn; Sussman, Betsy L; Uyeda, Jennifer; Wall, Darci J; Whitcomb, Bradford; Zelop, Carolyn M; Glanc, Phyllis

2017-11-01

There has been much interest in the identification of a successful ovarian cancer screening test, in particular, one that can detect ovarian cancer at an early stage and improve survival. We reviewed the currently available data from randomized and observational trials that examine the role of imaging for ovarian cancer screening in average-risk and high-risk women. We found insufficient evidence to recommend ovarian cancer screening, when considering the imaging modality (pelvic ultrasound) and population (average-risk postmenopausal women) for which there is the greatest available published evidence; randomized controlled trials have not demonstrated a mortality benefit in this setting. Screening high-risk women using pelvic ultrasound may be appropriate in some clinical situations; however, related data are limited because large, randomized trials have not been performed in this setting. The American College of Radiology Appropriateness Criteria are evidence-based guidelines for specific clinical conditions that are reviewed annually by a multidisciplinary expert panel. The guideline development and revision include an extensive analysis of current medical literature from peer reviewed journals and the application of well-established methodologies (RAND/UCLA Appropriateness Method and Grading of Recommendations Assessment, Development, and Evaluation or GRADE) to rate the appropriateness of imaging and treatment procedures for specific clinical scenarios. In those instances where evidence is lacking or equivocal, expert opinion may supplement the available evidence to recommend imaging or treatment. Copyright © 2017 American College of Radiology. Published by Elsevier Inc. All rights reserved.

ACR Appropriateness Criteria® Colorectal Cancer Screening.

Science.gov (United States)

Moreno, Courtney; Kim, David H; Bartel, Twyla B; Cash, Brooks D; Chang, Kevin J; Feig, Barry W; Fowler, Kathryn J; Garcia, Evelyn M; Kambadakone, Avinash R; Lambert, Drew L; Levy, Angela D; Marin, Daniele; Peterson, Christine M; Scheirey, Christopher D; Smith, Martin P; Weinstein, Stefanie; Carucci, Laura R

2018-05-01

This review summarizes the relevant literature regarding colorectal screening with imaging. For individuals at average or moderate risk for colorectal cancer, CT colonography is usually appropriate for colorectal cancer screening. After positive results on a fecal occult blood test or immunohistochemical test, CT colonography is usually appropriate for colorectal cancer detection. For individuals at high risk for colorectal cancer (eg, hereditary nonpolyposis colorectal cancer, ulcerative colitis, or Crohn colitis), optical colonoscopy is preferred because of its ability to obtain biopsies to detect dysplasia. After incomplete colonoscopy, CT colonography is usually appropriate for colorectal cancer screening for individuals at average, moderate, or high risk. The American College of Radiology Appropriateness Criteria are evidence-based guidelines for specific clinical conditions that are reviewed annually by a multidisciplinary expert panel. The guideline development and revision include an extensive analysis of current medical literature from peer reviewed journals and the application of well-established methodologies (RAND/UCLA Appropriateness Method and Grading of Recommendations Assessment, Development, and Evaluation or GRADE) to rate the appropriateness of imaging and treatment procedures for specific clinical scenarios. In those instances where evidence is lacking or equivocal, expert opinion may supplement the available evidence to recommend imaging or treatment. Copyright © 2018 American College of Radiology. Published by Elsevier Inc. All rights reserved.

Screening specifications for bedded salt, Salina Basin, New York and Ohio

International Nuclear Information System (INIS)

Brunton, G.D.; Laughon, R.B.; McClain, W.C.

1978-01-01

A survey of bedded salt deposits in New York and Ohio is planned to identify study areas for potential sites for radioactive waste disposal. Prior to the survey previous geological work related to these deposits will be reviewed. Preliminary screening specifications for the identification of study areas were derived for each of the geological evaluation criteria by application of the significant factors that will have an impact on the reconnaissance survey. These factors were selected by a review of the list of factors associated with each criterion. The procedure for the derivation of each screening specification is discussed. The screening specifications are the official Office of Waste Isolation values to be used for the first-cut acceptance for bedded salt study areas in Ohio and New York. The specifications will be reevaluated and refined for more-detailed investigations at each study area that passes the screening test. The derivation of the screening specifications is illustrated by (1) a statement of the geological evaluation criterion, (2) a discussion of the pertinent factors affecting the criterion, and (3) the evaluation of the value of the specification

Targeted Screening With Combined Age- and Morphology-Based Criteria Enriches Detection of Lynch Syndrome in Endometrial Cancer.

Science.gov (United States)

Lin, Douglas I; Hecht, Jonathan L

2016-06-01

Endometrial cancer is associated with Lynch syndrome in 2% to 6% of cases. Adequate screening may prevent of a second cancer and incident cancers in family members via risk-reducing strategies. The goal of the study was to evaluate the detection rate of Lynch syndrome via a targeted screening approach. In 2009, we incorporated targeted Lynch syndrome screening via immunohistochemistry for MLH1, PMS2, MSH2, and MSH6, followed by MLH1 promoter hypermethylation, in select cases of endometrial carcinoma. Criteria for patient selection included (1) all patients Lynch syndrome. Therefore, targeted screening with combined age and morphology based criteria enriches detection of Lynch syndrome in endometrial cancer. However, the detection rate is lower than the rates from published series that offer universal screening. © The Author(s) 2016.

The criteria for metabolic syndrome and the national health screening and education system in Japan

Directory of Open Access Journals (Sweden)

Kazumasa Yamagishi

2017-01-01

Full Text Available Two major definitions of metabolic syndrome have been proposed. One focuses on the accumulation of risk factors, a measure used by the American Heart Association (AHA and the National Heart, Lung, and Blood Institute (NHLBI; the other focuses on abdominal obesity, a measure used by the International Diabetes Federation (IDF and the Japanese government. The latter definition takes waist circumference (WC into consideration as an obligatory component, whereas the former does not. In 2009, the IDF, NHLBI, AHA, and other organizations attempted to unify these criteria; as a result, WC is no longer an obligatory component of those systems, while it remains obligatory in the Japanese criteria. In 2008, a new Japanese cardiovascular screening and education system focused on metabolic syndrome was launched. People undergoing screening are classified into three groups according to the presence of abdominal obesity and the number of metabolic risk factors, and receive health educational support from insurers. This system has yielded several beneficial outcomes: the visibility of metabolic syndrome at the population level has drastically improved; preventive measures have been directed toward metabolic syndrome, which is expected to become more prevalent in future generations; and a post-screening education system has been established. However, several problems with the current system have been identified and are under debate. In this review, we discuss topics related to metabolic syndrome, including (1 the Japanese criteria for metabolic syndrome; (2 metabolic syndrome and the universal health screening and education system; and (3 recent debates about Japanese criteria for metabolic syndrome.

Geology and recognition criteria for roll-type uranium deposits in continental sandstones. Final report

International Nuclear Information System (INIS)

Harshman, E.N.; Adams, S.S.

1981-01-01

The study of roll-type deposits during the past 20 years, since the first description of a deposit in the United States, has developed general concepts of ore formation which are accepted widely and are compatible with available data. If this were not the case the concepts would not have endured and could not have been so successfully applied to exploration using the relations of altered-unaltered sandstone. The comparative simplicity of the model, and the ease with which it has been applied to exploration have, oddly enough, probably inhibited detailed studies of ore districts that would have provided data now needed for refinement of ore controls for exploration and resource assessment programs. The most thorough study of a roll-type district was that of the Shirley Basin which is drawn on heavily in this report. The general concept of roll-type formation provides a strong basis for the development of geological observations and guides, or recognition criteria, for resource studies and exploration. Indeed, industry has been developing and using them for 20 years. As the objective of this study was to identify the most useful recognition criteria and develop a method for their systematic use in resource studies and exploration, the study is best summarized by reference to the important geological observations about roll-type deposits

Screening for Lynch syndrome using risk assessment criteria in patients with ovarian cancer.

Science.gov (United States)

Takeda, Takashi; Tsuji, Kosuke; Banno, Kouji; Yanokura, Megumi; Kobayashi, Yusuke; Tominaga, Eiichiro; Aoki, Daisuke

2018-05-01

Lynch syndrome is a cancer predisposition syndrome caused by germline mutation of DNA mismatch repair (MMR) genes. Lynch syndrome only causes about 0.4% of cases of ovarian cancer, which suggests that universal screening may not be cost-efficient. However, the frequency of Lynch syndrome in ovarian cancer is unclear in the Asian population. The goal of the study was to investigate a screening strategy using family history. The subjects were 129 patients with ovarian cancer. Clinical and family history were collected using a self-administered questionnaire, and Society of Gynecologic Oncology (SGO) criteria 2007 and PREMM₅ were used for risk assessment. Microsatellite instability, immunohistochemistry, and methylation of MMR genes were analyzed. Of the 129 cases, 25 (19.4%) met the SGO criteria, and 4 of these 25 had MSI-high and MMR deficiency. Two cases had loss of MSH2 and MSH6, indicating MSH2 mutation, and the other two had loss of MLH1 and PMS2, including one without MLH1 methylation indicating MLH1 mutation. These results show that screening using family history can detect Lynch syndrome in 12.0% (3/25) of ovarian cancer cases. The 3 cases were positive for PREMM₅, but negative for Amsterdam II criteria and revised Bethesda guidelines. Genetic testing in one case with MSH2 and MSH6 deficiency confirmed the diagnosis of Lynch syndrome with MSH2 mutation. This is the first study of screening for Lynch syndrome in ovarian cancer using clinical and family history in an Asian population. This approach may be effective for diagnosis in these patients. Copyright © 2018. Asian Society of Gynecologic Oncology, Korean Society of Gynecologic Oncology.

Geology and recognition criteria for uraniferous humate deposits, Grants Uranium Region, New Mexico. Final report

International Nuclear Information System (INIS)

Adams, S.S.; Saucier, A.E.

1981-01-01

The geology of the uraniferous humate uranium deposits of the Grants Uranium Region, northwestern New Mexico, is summarized. The most important conclusions of this study are enumerated. Although the geologic characteristics of the uraniferous humate deposits of the Grants Uranium Region are obviously not common in the world, neither are they bizarre or coincidental. The source of the uranium in the deposits of the Grants Uranium Region is not known with certainty. The depositional environment of the host sediments was apparently the mid and distal portions of a wet alluvial fan system. The influence of structural control on the location and accumulation of the host sediments is now supported by considerable data. The host sediments possess numerous important characteristics which influenced the formation of uraniferous humate deposits. Ilmenite-magnetite distribution within potential host sandstones is believed to be the simplest and most useful regional alteration pattern related to this type of uranium deposit. A method is presented for organizing geologic observations into what is referred to as recognition criteria. The potential of the United States for new districts similar to the Grants Uranium Region is judged to be low based upon presently available geologic information. Continuing studies on uraniferous humate deposits are desirable in three particular areas

Can streamlined multi-criteria decision analysis be used to implement shared decision making for colorectal cancer screening?

Science.gov (United States)

Dolan, James G.; Boohaker, Emily; Allison, Jeroan; Imperiale, Thomas F.

2013-01-01

Background Current US colorectal cancer screening guidelines that call for shared decision making regarding the choice among several recommended screening options are difficult to implement. Multi-criteria decision analysis (MCDA) is an established methodology well suited for supporting shared decision making. Our study goal was to determine if a streamlined form of MCDA using rank order based judgments can accurately assess patients’ colorectal cancer screening priorities. Methods We converted priorities for four decision criteria and three sub-criteria regarding colorectal cancer screening obtained from 484 average risk patients using the Analytic Hierarchy Process (AHP) in a prior study into rank order-based priorities using rank order centroids. We compared the two sets of priorities using Spearman rank correlation and non-parametric Bland-Altman limits of agreement analysis. We assessed the differential impact of using the rank order-based versus the AHP-based priorities on the results of a full MCDA comparing three currently recommended colorectal cancer screening strategies. Generalizability of the results was assessed using Monte Carlo simulation. Results Correlations between the two sets of priorities for the seven criteria ranged from 0.55 to 0.92. The proportions of absolute differences between rank order-based and AHP-based priorities that were more than ± 0.15 ranged from 1% to 16%. Differences in the full MCDA results were minimal and the relative rankings of the three screening options were identical more than 88% of the time. The Monte Carlo simulation results were similar. Conclusion Rank order-based MCDA could be a simple, practical way to guide individual decisions and assess population decision priorities regarding colorectal cancer screening strategies. Additional research is warranted to further explore the use of these methods for promoting shared decision making. PMID:24300851

GEOLOGIC SCREENING CRITERIA FOR SEQUESTRATION OF CO2 IN COAL: QUANTIFYING POTENTIAL OF THE BLACK WARRIOR COALBED METHANE FAIRWAY, ALABAMA

Energy Technology Data Exchange (ETDEWEB)

Jack C. Pashin; Richard E. Carroll; Richard H. Groshong, Jr.; Dorothy E. Raymond; Marcella McIntyre; J. Wayne Payton

2003-01-01

Sequestration of CO{sub 2} in coal has potential to reduce greenhouse gas emissions from coal-fired power plants while enhancing coalbed methane recovery. Data from more than 4,000 coalbed methane wells in the Black Warrior basin of Alabama provide an opportunity to quantify the carbon sequestration potential of coal and to develop a geologic screening model for the application of carbon sequestration technology. This report summarizes stratigraphy and sedimentation, structural geology, geothermics, hydrology, coal quality, gas capacity, and production characteristics of coal in the Black Warrior coalbed methane fairway and the implications of geology for carbon sequestration and enhanced coalbed methane recovery. Coal in the Black Warrior basin is distributed among several fluvial-deltaic coal zones in the Lower Pennsylvanian Pottsville Formation. Most coal zones contain one to three coal beds that are significant targets for coalbed methane production and carbon sequestration, and net coal thickness generally increases southeastward. Pottsville strata have effectively no matrix permeability to water, so virtually all flow is through natural fractures. Faults and folds influence the abundance and openness of fractures and, hence, the performance of coalbed methane wells. Water chemistry in the Pottsville Formation ranges from fresh to saline, and zones with TDS content lower than 10,000 mg/L can be classified as USDW. An aquifer exemption facilitating enhanced recovery in USDW can be obtained where TDS content is higher than 3,000 mg/L. Carbon dioxide becomes a supercritical fluid above a temperature of 88 F and a pressure of 1,074 psi. Reservoir temperature exceeds 88 F in much of the study area. Hydrostatic pressure gradients range from normal to extremely underpressured. A large area of underpressure is developed around closely spaced longwall coal mines, and areas of natural underpressure are distributed among the coalbed methane fields. The mobility and

Disappointing performance of literature-derived selective screening criteria for asymptomatic Chlamydia trachomatis infection in an inner-city population

NARCIS (Netherlands)

van Valkengoed, I G; Boeke, A J; Morré, S A; van den Brule, A J; Meijer, C J; Devillé, W; Bouter, L M

2000-01-01

BACKGROUND: In an inner-city population with a low prevalence of Chlamydia trachomatis infection, selective screening may be indicated to increase the efficiency of screening. GOAL: To evaluate the performance of sets of selective screening criteria for asymptomatic Chlamydia trachomatis infection

U.S. Department of Energy's site screening, site selection, and initial characterization for storage of CO2 in deep geological formations

Science.gov (United States)

Rodosta, T.D.; Litynski, J.T.; Plasynski, S.I.; Hickman, S.; Frailey, S.; Myer, L.

2011-01-01

The U.S. Department of Energy (DOE) is the lead Federal agency for the development and deployment of carbon sequestration technologies. As part of its mission to facilitate technology transfer and develop guidelines from lessons learned, DOE is developing a series of best practice manuals (BPMs) for carbon capture and storage (CCS). The "Site Screening, Site Selection, and Initial Characterization for Storage of CO2 in Deep Geological Formations" BPM is a compilation of best practices and includes flowchart diagrams illustrating the general decision making process for Site Screening, Site Selection, and Initial Characterization. The BPM integrates the knowledge gained from various programmatic efforts, with particular emphasis on the Characterization Phase through pilot-scale CO2 injection testing of the Validation Phase of the Regional Carbon Sequestration Partnership (RCSP) Initiative. Key geologic and surface elements that suitable candidate storage sites should possess are identified, along with example Site Screening, Site Selection, and Initial Characterization protocols for large-scale geologic storage projects located across diverse geologic and regional settings. This manual has been written as a working document, establishing a framework and methodology for proper site selection for CO2 geologic storage. This will be useful for future CO2 emitters, transporters, and storage providers. It will also be of use in informing local, regional, state, and national governmental agencies of best practices in proper sequestration site selection. Furthermore, it will educate the inquisitive general public on options and processes for geologic CO2 storage. In addition to providing best practices, the manual presents a geologic storage resource and capacity classification system. The system provides a "standard" to communicate storage and capacity estimates, uncertainty and project development risk, data guidelines and analyses for adequate site characterization, and

Geological Storage of CO2. Site Selection Criteria; Almacenamiento Geologico de CO2. Criterios de Selecci0n de Emplazamientos

Energy Technology Data Exchange (ETDEWEB)

Ruiz, C; Martinez, R; Recreo, F; Prado, P; Campos, R; Pelayo, M; Losa, A de la; Hurtado, A; Lomba, L; Perez del Villar, L; Ortiz, G; Sastre, J; Zapatero, M A; Suarez, I; Arenillas, A

2007-09-18

In year 2002 the Spanish Parliament unanimously passed the ratification of the Kyoto Protocol, signed December 1997, compromising to limiting the greenhouse gas emissions increase. Later on, the Environment Ministry submitted the Spanish National Assignment Emissions Plan to the European Union and in year 2005 the Spanish Greenhouse Gas market started working, establishing taxes to pay in case of exceeding the assigned emissions limits. So, the avoided emissions of CO2 have now an economic value that is promoting new anthropogenic CO2 emissions reduction technologies. Carbon Capture and Storage (CCS) are among these new technological developments for mitigating or eliminate climate change. CO2 can be stored in geological formations such as depleted oil or gas fields, deep permeable saline water saturated formations and unmailable coal seams, among others. This report seeks to establish the selection criteria for suitable geological formations for CO2 storage in the Spanish national territory, paying attention to both the operational and performance requirements of these storage systems. The report presents the physical and chemical properties and performance of CO2 under storage conditions, the transport and reaction processes of both supercritical and gaseous CO2, and CO2 trapping mechanisms in geological formations. The main part of the report is devoted to geological criteria at watershed, site and formation scales. (Author) 100 refs.

An Overview of Geologic Carbon Sequestration Potential in California

Energy Technology Data Exchange (ETDEWEB)

Cameron Downey; John Clinkenbeard

2005-10-01

As part of the West Coast Regional Carbon Sequestration Partnership (WESTCARB), the California Geological Survey (CGS) conducted an assessment of geologic carbon sequestration potential in California. An inventory of sedimentary basins was screened for preliminary suitability for carbon sequestration. Criteria included porous and permeable strata, seals, and depth sufficient for critical state carbon dioxide (CO{sub 2}) injection. Of 104 basins inventoried, 27 met the criteria for further assessment. Petrophysical and fluid data from oil and gas reservoirs was used to characterize both saline aquifers and hydrocarbon reservoirs. Where available, well log or geophysical information was used to prepare basin-wide maps showing depth-to-basement and gross sand distribution. California's Cenozoic marine basins were determined to possess the most potential for geologic sequestration. These basins contain thick sedimentary sections, multiple saline aquifers and oil and gas reservoirs, widespread shale seals, and significant petrophysical data from oil and gas operations. Potential sequestration areas include the San Joaquin, Sacramento, Ventura, Los Angeles, and Eel River basins, followed by the smaller Salinas, La Honda, Cuyama, Livermore, Orinda, and Sonoma marine basins. California's terrestrial basins are generally too shallow for carbon sequestration. However, the Salton Trough and several smaller basins may offer opportunities for localized carbon sequestration.

Comparison of UK and US screening criteria for detection of retinopathy of prematurity in a developing nation.

Science.gov (United States)

Ugurbas, Silay Canturk; Gulcan, Hande; Canan, Handan; Ankarali, Handan; Torer, Birgin; Akova, Yonca Aydın

2010-12-01

To determine the incidence, risk factors, and appropriateness of differing guidelines in developed nations for screening for retinopathy of prematurity (ROP) in a single nursery in a large urban city in southern Turkey. The records of 260 premature infants born ≤34 weeks in a single tertiary unit were retrospectively reviewed for ROP risk factors and diagnosis. Applicability of UK and US criteria were assessed by the use of receiver operating characteristic curves. ROP of any stage was present in 60 infants (23%); ROP requiring treatment was seen in 30 (11.5%). Univariate analysis showed a significant relationship among the following factors: gestational age, birth weight, total duration of supplemental oxygen, duration of mechanical ventilation, respiratory distress syndrome, anemia, and intraventricular hemorrhage (p < 0.0001). Multiple logistic regression analysis showed gestational age (p = 0.039), birth weight (p = 0.05), respiratory distress syndrome (p = 0.05), and anemia (p = 0.004) as independent predictors of ROP requiring treatment. Area under curve for gestational age alone for diagnosing stage 2 or greater ROP was 0.824 ± 0.03 (p = 0.0001) and for birth weight alone was 0.808 ± 0.03 (p = 0.0001). UK screening criteria detected all stage 2 and greater ROP; US screening criteria missed 2 infants with stage 2 ROP but detected all treatment-requiring disease. Adoption of these screening criteria would have reduced unnecessary examinations by either 21% (UK) or 37% (US). UK and US criteria improved the detection accuracy for ROP requiring treatment in Turkey and should be studied for other developing nations. Copyright © 2010 American Association for Pediatric Ophthalmology and Strabismus. Published by Mosby, Inc. All rights reserved.

HYDROGEOLOGICAL AND ENGINEERING-GEOLOGICAL CRITERIA FOR THE SELECTION OF NUCLEAR POWER PLANT LOCATION CASE OF THE SAVA RIVERBASIN IN CROATIA

Directory of Open Access Journals (Sweden)

Darko Mayer

1991-12-01

Full Text Available Possible impacts of geological characteristics on safety of nuclear power plants and impacts of nuclear power plants on groundwaters are discussed. Potential locations in view of these criteria are evaluated (the paper is published in Croatian.

Development of site selection criteria for radioactive waste disposal in view of favourable geological settings in Germany

Energy Technology Data Exchange (ETDEWEB)

Baltes, B.; Brewitz, W. [Gesellschaft fuer Anlagen- und Reaktorsicherheit (GRS) mbH, Cologne (Germany)

2001-07-01

In Germany it is intended to dispose of all types of radioactive waste in deep geological formations. Since the government has doubts regarding the suitability of the Gorleben site, further sites in different host rock formations have to be investigated. This investigation process has to be carried out with respect to technical suitability and safety as well as to public acceptance. A Committee has been established whose mandate is to develop a comprehensible procedure for the selection of sites for radioactive waste disposal in Germany. The Committee developed an iterative procedure which provides, besides the increase of transparency, the necessary flexibility in dealing with assessment results. The method is governed by geo-scientific and social-scientific criteria that are presented in this paper. 7 steps have been identified in the procedure: 1) exclusion of areas with obviously unfavourable conditions, 2) identification of areas with favourable geological settings, 3) exclusion of areas for socio-scientific reasons, 4) identification of regions with favourable conditions and ranking of regions, 5) identification of sites for further identification, 6) above-ground site investigation and ranking of potentially suitable sites, and 7) identification of sites for suitability investigations. The first 3 steps give the remaining areas that meet the minimum requirements. The criteria of the first 3 steps are: extensive vertical movements, active disturbance zones, seismic activity and volcanic activity, as for the 4 last steps criteria are based on geo- and socio- scientific weighing, voluntariness and regional mediation. (A.C.)

Development of site selection criteria for radioactive waste disposal in view of favourable geological settings in Germany

International Nuclear Information System (INIS)

Baltes, B.; Brewitz, W.

2001-01-01

In Germany it is intended to dispose of all types of radioactive waste in deep geological formations. Since the government has doubts regarding the suitability of the Gorleben site, further sites in different host rock formations have to be investigated. This investigation process has to be carried out with respect to technical suitability and safety as well as to public acceptance. A Committee has been established whose mandate is to develop a comprehensible procedure for the selection of sites for radioactive waste disposal in Germany. The Committee developed an iterative procedure which provides, besides the increase of transparency, the necessary flexibility in dealing with assessment results. The method is governed by geo-scientific and social-scientific criteria that are presented in this paper. 7 steps have been identified in the procedure: 1) exclusion of areas with obviously unfavourable conditions, 2) identification of areas with favourable geological settings, 3) exclusion of areas for socio-scientific reasons, 4) identification of regions with favourable conditions and ranking of regions, 5) identification of sites for further identification, 6) above-ground site investigation and ranking of potentially suitable sites, and 7) identification of sites for suitability investigations. The first 3 steps give the remaining areas that meet the minimum requirements. The criteria of the first 3 steps are: extensive vertical movements, active disturbance zones, seismic activity and volcanic activity, as for the 4 last steps criteria are based on geo- and socio- scientific weighing, voluntariness and regional mediation. (A.C.)

Dysphagia screening after acute stroke: a quality improvement project using criteria-based clinical audit.

Science.gov (United States)

Sivertsen, Jorun; Graverholt, Birgitte; Espehaug, Birgitte

2017-01-01

Dysphagia is common after stroke and represents a major risk factor for developing aspiration pneumonia. Early detection can reduce the risk of pulmonary complications and death. Despite the fact that evidence-based guidelines recommend screening for swallowing deficit using a standardized screening tool, national audits has identified a gap between practice and this recommendation. The aim was to determine the level of adherence to an evidence-based recommendation on swallow assessment and to take actions to improve practice if necessary. We carried out a criteria-based clinical audit (CBCA) in a small stroke unit at a Norwegian hospital. Patients with hemorrhagic stroke, ischemic stroke and transient ischemic attack were included. A power calculation informed the number of included patients at baseline ( n  = 80) and at re-audit ( n  = 35). We compared the baseline result with the evidence-based criteria and gave feedback to management and staff. A brainstorming session, a root-cause analysis and implementation science were used to inform the quality improvement actions which consisted of workshops, use of local opinion leaders, manual paper reminders and feedback. We completed a re-audit after implementation. Percentages and median are reported with 95% confidence intervals (CI). Among 88 cases at baseline, documentation of swallow screening was complete for 6% (95% CI 2-11). In the re-audit ( n  = 51) 61% (95% CI 45-74) had a complete screening. A CBCA involving management and staff, and using multiple tailored intervention targeting barriers, led to greater adherence with the recommendation for screening stroke patients for dysphagia.

Annual Earnings Announcements and Market Reaction: The Influence of Screening Criteria for Thin Trading

DEFF Research Database (Denmark)

Møller, Peder Fredslund; Thinggaard, Frank; Lønroth, Helle L.

2001-01-01

This paper presents the findings of an event study of the Danish stock market price reactions to annual earnings announcements in the period 1993-1997, with a dual purpose. The primary purpose is to find out how market reactions vary with different screening criteria for thin trading. Our findings...... on this point suggest that the Danish stock market, although small, seems to have different segments of shares in relation to earnings announcements. Applying different screening criteria we find differences both in terms of how quickly the market reacts to earnings announcements and the relative quality...... purpose of our study is briefly to compare our findings with those of a similar study for the period 1971-1981. The aim is to find indications of developments in the Danish market's reactions to earnings announcements since that study. We find distinct indications that the Danish stock market in some...

NCCN Guidelines as a Model of Extended Criteria for Lung Cancer Screening.

Science.gov (United States)

McKee, Brady J; Regis, Shawn; Borondy-Kitts, Andrea K; Hashim, Jeffrey A; French, Robert J; Wald, Christoph; McKee, Andrea B

2018-04-01

Background: This review assessed the performance of patients in NCCN high-risk group 2 in a clinical CT lung screening (CTLS) program. Methods: We retrospectively reviewed screening results for all patients from our institution undergoing clinical CTLS from January 2012 through December 2016, with follow-up through June 2017. To qualify for screening, patients had to meet the NCCN Guidelines high-risk criteria for CTLS, have a physician order for screening, be asymptomatic, be lung cancer-free for 5 years, and have no known metastatic disease. We compared demographics and screening performance of NCCN high-risk groups 1 and 2 across >4 rounds of screening. Screening metrics assessed included rates of positive and suspicious examinations, significant incidental and infectious/inflammatory findings, false negatives, and cancer detection. We also compared cancer stage and histology detected in each NCCN high-risk group. Results: A total of 2,927 individuals underwent baseline screening, of which 698 (24%) were in NCCN group 2. On average, group 2 patients were younger (60.6 vs 63.1 years), smoked less (38.8 vs 50.8 pack-years), had quit longer (18.1 vs 6.3 years), and were more often former smokers (61.4% vs 44.2%). Positive and suspicious examination rates, false negatives, and rates of infectious/inflammatory findings were equivalent in groups 1 and 2 across all rounds of screening. An increased rate of cancer detection was observed in group 2 during the second annual (T2) screening round (2.7% vs 0.5%; P =.005), with no difference in the other screening rounds: baseline (T0; 2% vs 2.3%; P =.61), first annual (T1; 1.2% vs 1.7%; P =.41), and third annual and beyond (≥T3; 1.2% vs 1.1%; P =1.00). Conclusions: CTLS appears to be equally effective in both NCCN high-risk groups. Copyright © 2018 by the National Comprehensive Cancer Network.

Economic Screening of Geologic Sequestration Options in the United States with a Carbon Management Geographic Information System

Energy Technology Data Exchange (ETDEWEB)

Dahowski, Robert T.(BATTELLE (PACIFIC NW LAB)); Dooley, James J.(BATTELLE (PACIFIC NW LAB)); Brown, Daryl R.(BATTELLE (PACIFIC NW LAB)); Stephan, Alex J.(BATTELLE (PACIFIC NW LAB)); Badie I. Morsi

2001-10-19

Developing a carbon management strategy is a formidable task for nations as well as individual companies. It is often difficult to understand what options are available, let alone determine which may be optimal. In response to the need for a better understanding of complex carbon management options, Battelle has developed a state-of-the-art Geographic Information System (GIS) model with economic screening capability focused on carbon capture and geologic sequestration opportunities in the United States. This paper describes the development of this GIS-based economic screening model and demonstrates its use for carbon management analysis.

The two most popular malnutrition screening tools in the light of the new ESPEN consensus definition of the diagnostic criteria for malnutrition.

Science.gov (United States)

Poulia, Kalliopi-Anna; Klek, Stanislaw; Doundoulakis, Ioannis; Bouras, Emmanouil; Karayiannis, Dimitrios; Baschali, Aristea; Passakiotou, Marili; Chourdakis, Michael

2017-08-01

The new definition of malnutrition in adults proposed recently by The European Society for Clinical Nutrition and Metabolism (ESPEN) changed the view on the issue and raised the question of the reliability of available diagnostic tools. Therefore, the aim of this study was to verify the accuracy of the two most commonly used screening tools by comparing their findings with the new ESPEN criteria. Nutritional screening was performed in 1146 (median age 60 years, interquartile range: 44-73 years, 617 males, 529 females) patients on admission to hospitals with two nutritional screening tools: Nutritional Risk Screening 2002 (NRS2002) and Malnutrition Universal Screening Tool (MUST). The screening results were then compared to the ESPEN new diagnostic criteria for malnutrition. According to the NRS2002 13.5% and 27.9% of the outpatients and hospitalized patients respectively were found to be at moderate/high risk of malnutrition. With the use of MUST 9.1% and 14.9% of the outpatients and hospitalized patients respectively were found to be at moderate/high risk of malnutrition. According to the ESPEN diagnostic criteria 6.4% and 11.3% of outpatients and hospitalized patients respectively were classified as malnourished. MUST was found to be better correlated to the latter for both outpatients (K = 0.777, p malnutrition screening tool in the light of the new ESPEN definition for malnutrition. According to our results, MUST was better correlated with ESPEN criteria for the definition of malnutrition, leading us to the conclusion that it can more efficiently identify the malnourished patients, during the screening process. Copyright © 2016 Elsevier Ltd and European Society for Clinical Nutrition and Metabolism. All rights reserved.

Repository operational criteria analysis

International Nuclear Information System (INIS)

Hageman, J.P.; Chowdhury, A.H.

1992-08-01

The objective of the ''Repository Operational Criteria (ROC) Feasibility Studies'' (or ROC task) was to conduct comprehensive and integrated analyses of repository design, construction, and operations criteria in 10 CFR Part 60 regulations, considering the interfaces and impacts of any potential changes to those regulations. The study addresses regulatory criteria related to the preclosure aspects of the geologic repository. The study task developed regulatory concepts or potential repository operational criteria (PROC) based on analysis of a repository's safety functions and other regulations for similar facilities. These regulatory concepts or PROC were used as a basis to assess the sufficiency and adequacy of the current criteria in 10 CFR Part 60. Where the regulatory concepts were same as current operational criteria, these criteria were referenced. The operations criteria referenced or the PROC developed are given in this report. Detailed analyses used to develop the regulatory concepts and any necessary PROC for those regulations that may require a minor change are also presented. The results of the ROC task showed a need for further analysis and possible major rule change related to the design bases of a geologic repository operations area, siting, and radiological emergency planning

Validation of the Gambling Disorder Screening Questionnaire, a self-administered diagnostic questionnaire for gambling disorder based on the DSM-5 criteria.

Science.gov (United States)

Villella, Corrado; Pascucci, Marco; de Waure, Chiara; Bellomo, Antonello; Conte, Gianluigi

2016-01-01

The DSM-5 has modified the diagnostic criteria for gambling disorder, compared to the fourth edition of the manual; new diagnostic instruments are therefore needed. This study evaluated the psychometric characteristics of the Gambling Disorder Screening Questionnaire (GDSQ), a self-report questionnaire based on the DSM-IV and DSM-5 criteria for Gambling Disorder, measuring its validity, internal consistency, and submitting the questionnaire to a principal components analysis. 71 patients from a gambling disorder outpatient clinic and 70 controls were evaluated with the GDSQ, the South Oaks Gambling Screen (SOGS), and a psychiatric interview. The test showed a good sensibility, specificity, internal consistency, concurrent validity with the SOGS. The exclusion of the “illegal acts” item, and the lowering of the cut-off score to four positive items, as suggested by the DSM-5 criteria, improved the test sensibility and internal consistency. The GDSQ can be considered a useful screening test for Gambling Disorder. Furthermore, this study confirms the improved diagnostic accuracy of the criteria listed in the fifth edition of the Diagnostic and Statistical Manual of Mental Disorders, compared to the previous edition.

Using geologic conditions and multiattribute decision analysis to determine the relative favorability of selected areas for siting a high-level radioactive waste repository

International Nuclear Information System (INIS)

Harrison, W.; Edgar, D.E.; Baker, C.H.

1988-05-01

A method is presented for determining the relative favorability of geologically complex areas for isolating high-level radioactive wastes. In applying the method to the northeastern region of the United States, seismicity and tectonic activity were the screening criteria used to divide the region into three areas of increasing seismotectonic risk. Criteria were then used to subdivide the area of lowest seismotectonic risk into six geologically distinct subareas including characteristics, surface-water and groundwater hydrology, potential human intrusion, site geometry, surface characteristics, and tectonic environment. Decision analysis was then used to identify the subareas most favorable from a geologic standpoint for further investigation, with a view to selecting a site for a repository. Three subareas (parts of northeastern Vermont, northern New Hampshire, and western Maine) were found to be the most favorable, using this method and existing data. However, because this study assessed relative geologic favorability, no conclusions should be drawn concerning the absolute suitability of individual subareas for high-level radioactive waste isolation. 34 refs., 7 figs., 20 tabs

Geotherm: the U.S. geological survey geothermal information system

Science.gov (United States)

Bliss, J.D.; Rapport, A.

1983-01-01

GEOTHERM is a comprehensive system of public databases and software used to store, locate, and evaluate information on the geology, geochemistry, and hydrology of geothermal systems. Three main databases address the general characteristics of geothermal wells and fields, and the chemical properties of geothermal fluids; the last database is currently the most active. System tasks are divided into four areas: (1) data acquisition and entry, involving data entry via word processors and magnetic tape; (2) quality assurance, including the criteria and standards handbook and front-end data-screening programs; (3) operation, involving database backups and information extraction; and (4) user assistance, preparation of such items as application programs, and a quarterly newsletter. The principal task of GEOTHERM is to provide information and research support for the conduct of national geothermal-resource assessments. The principal users of GEOTHERM are those involved with the Geothermal Research Program of the U.S. Geological Survey. Information in the system is available to the public on request. ?? 1983.

Field Geology/Processes

Science.gov (United States)

Allen, Carlton; Jakes, Petr; Jaumann, Ralf; Marshall, John; Moses, Stewart; Ryder, Graham; Saunders, Stephen; Singer, Robert

1996-01-01

The field geology/process group examined the basic operations of a terrestrial field geologist and the manner in which these operations could be transferred to a planetary lander. Four basic requirements for robotic field geology were determined: geologic content; surface vision; mobility; and manipulation. Geologic content requires a combination of orbital and descent imaging. Surface vision requirements include range, resolution, stereo, and multispectral imaging. The minimum mobility for useful field geology depends on the scale of orbital imagery. Manipulation requirements include exposing unweathered surfaces, screening samples, and bringing samples in contact with analytical instruments. To support these requirements, several advanced capabilities for future development are recommended. Capabilities include near-infrared reflectance spectroscopy, hyper-spectral imaging, multispectral microscopy, artificial intelligence in support of imaging, x ray diffraction, x ray fluorescence, and rock chipping.

Prospective targets of geological exploration in the Siberian platform and criteria of their feasibility

Directory of Open Access Journals (Sweden)

D.V. Milyaev

2017-06-01

Full Text Available The relevance of the study is due to the reducing number of prospective blocks remaining unlicensed in Eastern Siberia and the need for feasibility study of the remaining potentially attractive blocks. The aim of the study is evaluation of the resource potential and allocation of new prospective license blocks in Eastern Siberia based on geological and economic criteria. The methods and instruments used in the study. To perform the economic analysis of resources and to assess the efficiency and risks of subsoil exploration and development, the authors used the results of in-house regional geological and geophysical modelling and economic research. A feasibility study of each potential pool was conducted on the author’s automated complex GeoProfi. The authors used probabilistic analysis and the cash flow discounting method to draw up an expert forecast. The results of the study. The study covers the present state and development prospects of oil and gas fields in the Siberian Platform within the Krasnoyarsk Territory, the Irkutsk Region, and the Sakha (Yakutia Republic. The top priority petroleum zones were analysed. A feasibility study of selected areas was conducted. The income density and feasible recoverable reserves density were mapped. The critical parameters that indicate unprofitable targets were calculated. The most feasible subsoil blocks were determined based on the correlation of economic and probability parameters.

Southeastern Regional Geologic Characterization Report. Executive summary. Final report

International Nuclear Information System (INIS)

1985-08-01

This Executive Summary of the final Southeastern Regional Geologic Characterization Report (RGCR) is issued primarily for public information purposes, and provides a general overview of the report. The complete RGCR presents available regional geologic information pertinent to siting a repository for high-level nuclear waste in crystalline rock in central Maryland; noncoastal Virginia, North Carolina, and South Carolina; and northern Georgia. For each of the states within the Southeastern Region, information is provided on the geologic disqualifying factor and the geologic regional screening variables to be used in region-to-area screening

A new set of qualitative reliability criteria to aid inferences on palaeomagnetic dipole moment variations through geological time

Directory of Open Access Journals (Sweden)

Andrew John Biggin

2014-10-01

Full Text Available Records of reversal frequency support forcing of the geodynamo over geological timescales but obtaining these for earlier times (e.g. the Precambrian is a major challenge. Changes in the measured virtual (axial dipole moment of the Earth, averaged over several millions of years or longer, also have the potential to constrain core and mantle evolution through deep time. There have been a wealth of recent innovations in palaeointensity methods, but there is, as yet, no comprehensive means for assessing the reliability of new and existing dipole moment data. Here we present a new set of largely qualitative reliability criteria for palaeointensity results at the site mean level, which we term QPI in reference to the long-standing Q criteria used for assessing palaeomagnetic poles. These represent the first attempt to capture the range of biasing agents applicable to palaeointensity measurements and to recognise the various approaches employed to obviate them. A total of 8 criteria are proposed and applied to 312 dipole moment estimates recently incorporated into the PINT global database. The number of these criteria fulfilled by a single dipole moment estimate (the QPI value varies between 1 and 6 in the examined dataset and has a median of 3. Success rates for each of the criteria are highly variable, but each criterion was met by at least a few results. The new criteria will be useful for future studies as a means of gauging the reliability of new and published dipole moment estimates.

Northeastern Regional Geologic Characterization Report: executive summary. Final report

International Nuclear Information System (INIS)

1985-08-01

This Executive Summary of the final Northeastern Regional Geologic Characterization Report (RGCR) is issued primarily for public information purposes and provides a general overview of the report. The complete RGCR presents available regional geologic information pertinent to siting a repository for high-level nuclear waste in crystalline rock in Connecticut, Maine, Massachusetts, New Hampshire, New Jersey, New York, Pennsylvania, Rhode Island, and Vermont. For each of the states within the Northeastern Region, information is provided on the geologic disqualifying factor and the geologic regional screening variables to be used in region-to-area screening. 5 refs., 3 figs

Mutagenicity screening: General principles and minimal criteria. Report of a committee of the European Environmental Mutagen Society

NARCIS (Netherlands)

Kilbey, B.J.; Igali, S.; Lohman, P.H.M.

1978-01-01

A statement of general principles and minimal criteria for the screening of chemicals for potential mutagenicity in man that may be used as guidelines for regulatory agencies and industrial organisations. To make clear the potentialities and current limitations of short-term mutagenicity testing for

Research on geological disposal

International Nuclear Information System (INIS)

Uchida, Masahiro

2011-01-01

The aims of this research are to develop criteria for reviewing acceptability of the adequacy of the result of Preliminary and Detailed Investigations submitted by the implementor, and to establish a basic policy to secure safety for safety review. In FY 2010, 13 geology/climate related events for development of acceptance criteria for reviewing the adequacy of the result of Preliminary and Detailed Investigations were extracted. And the accuracy of geophysical exploration methods necessary for the Preliminary Investigation was evaluated. Regarding the research for safety review, we developed an idea of safety concept of Japanese geological disposal, and analyzed basic safety functions to secure safety. In order to verify the groundwater flow evaluation methods developed in regulatory research, the hydrological and geochemical data at Horonobe, northern Hokkaido were obtained, and simulated result of regional groundwater flow were compared with measured data. And we developed the safety scenario of geology/climate related events categorized by geological and geomorphological properties. Also we created a system to check the quality of research results in Japan and other countries in order to utilize for safety regulation, and developed a database system to compile them. (author)

Improved exposure estimation in soil screening and cleanup criteria for volatile organic chemicals.

Science.gov (United States)

DeVaull, George E

2017-09-01

Soil cleanup criteria define acceptable concentrations of organic chemical constituents for exposed humans. These criteria sum the estimated soil exposure over multiple pathways. Assumptions for ingestion, dermal contact, and dust exposure generally presume a chemical persists in surface soils at a constant concentration level for the entire exposure duration. For volatile chemicals, this is an unrealistic assumption. A calculation method is presented for surficial soil criteria that include volatile depletion of chemical for these uptake pathways. The depletion estimates compare favorably with measured concentration profiles and with field measurements of soil concentration. Corresponding volatilization estimates compare favorably with measured data for a wide range of volatile and semivolatile chemicals, including instances with and without the presence of a mixed-chemical residual phase. Selected examples show application of the revised factors in estimating screening levels for benzene in surficial soils. Integr Environ Assess Manag 2017;13:861-869. © 2017 The Authors. Integrated Environmental Assessment and Management published by Wiley Periodicals, Inc. on behalf of Society of Environmental Toxicology & Chemistry (SETAC). © 2017 The Authors. Integrated Environmental Assessment and Management published by Wiley Periodicals, Inc. on behalf of Society of Environmental Toxicology & Chemistry (SETAC).

Preliminary selection criteria for the Yucca Mountain Project waste package container material

International Nuclear Information System (INIS)

Halsey, W.G.

1991-01-01

The Department of Energy's Yucca Mountain Project (YMP) is evaluating a site at Yucca Mountain in Nevada for construction of a geologic repository for the storage of high-level nuclear waste. Lawrence Livermore National Laboratory's (LLNL) Nuclear Waste Management Project (NWMP) has the responsibility for design, testing, and performance analysis of the waste packages. The design is performed in an iterative manner in three sequential phases (conceptual design, advanced conceptual design, and license application design). An important input to the start of the advanced conceptual design is the selection of the material for the waste containers. The container material is referred to as the 'metal barrier' portion of the waste package, and is the responsibility of the Metal Barrier Selection and Testing task at LLNL. The selection will consist of several steps. First, preliminary, material-independent selection criteria will be established based on the performance goals for the container. Second, a variety of engineering materials will be evaluated against these criteria in a screening process to identify candidate materials. Third, information will be obtained on the performance of the candidate materials, and final selection criteria and quantitative weighting factors will be established based on the waste package design requirements. Finally, the candidate materials will be ranked against these criteria to determine whether they meet the mandated performance requirements, and to provide a comparative score to choose the material for advanced conceptual design activities. This document sets forth the preliminary container material selection criteria to be used in screening candidate materials. 5 refs

North Central Regional Geologic Characterization Report. Executive summary. Final report

International Nuclear Information System (INIS)

1985-08-01

This Executive Summary of the final North Central Regional Geologic Characterization Report (RGCR) is issued primarily for public information purposes and provides a general overview of the report. The complete RGCR presents available regional geologic information pertinent to siting a repository for high-level nuclear waste in crystalline rock in Minnesota, Wisconsin, and the Upper Peninsula of Michigan. For each of the states within the North Central Region, information is provided on the geologic disqualifying factor and the geologic regional screening variables to be used in region-to-area screening

Comparison of QSOFA score and SIRS criteria as screening mechanisms for emergency department sepsis.

Science.gov (United States)

Haydar, Samir; Spanier, Matthew; Weems, Patricia; Wood, Samantha; Strout, Tania

2017-11-01

The Quick Sequential [Sepsis-related] Organ Failure Assessment (qSOFA) score has been shown to accurately predict mortality in septic patients and is part of recently proposed diagnostic criteria for sepsis. We sought to ascertain the sensitive of the score in diagnosing sepsis, as well as the diagnostic timeliness of the score when compared to traditional systemic inflammatory response syndrome (SIRS) criteria in a population of emergency department (ED) patients treated in the ED, admitted, and subsequently discharged with a diagnosis of sepsis. Electronic health records of 200 patients who were treated for suspected sepsis in our ED and ultimately discharged from our hospital with a diagnosis of sepsis were randomly selected for review from a population of adult ED patients (N=1880). Data extracted included the presence of SIRS criteria and the qSOFA score as well as time required to meet said criteria. In this cohort, 94.5% met SIRS criteria while in the ED whereas only 58.3% met qSOFA. The mean time from arrival to SIRS documentation was 47.1min (95% CI: 36.5-57.8) compared to 84.0min (95% CI: 62.2-105.8) for qSOFA. The median ED "door" to positive SIRS criteria was 12min and 29min for qSOFA. Although qSOFA may be valuable in predicting sepsis-related mortality, it performed poorly as a screening tool for identifying sepsis in the ED. As the time to meet qSOFA criteria was significantly longer than for SIRS, relying on qSOFA alone may delay initiation of evidence-based interventions known to improve sepsis-related outcomes. Copyright © 2017 Elsevier Inc. All rights reserved.

Screening and ranking framework (SRF) for geologic CO2 storagesite selection on the basis of HSE risk

Energy Technology Data Exchange (ETDEWEB)

Oldenburg, Curtis M.

2006-11-27

A screening and ranking framework (SRF) has been developedto evaluate potential geologic carbon dioxide (CO2) storage sites on thebasis of health, safety, and environmental (HSE) risk arising from CO2leakage. The approach is based on the assumption that CO2 leakage risk isdependent on three basic characteristics of a geologic CO2 storage site:(1) the potential for primary containment by the target formation; (2)the potential for secondary containment if the primary formation leaks;and (3) the potential for attenuation and dispersion of leaking CO2 ifthe primary formation leaks and secondary containment fails. Theframework is implemented in a spreadsheet in which users enter numericalscores representing expert opinions or published information along withestimates of uncertainty. Applications to three sites in Californiademonstrate the approach. Refinements and extensions are possible throughthe use of more detailed data or model results in place of propertyproxies.

Geological disposal system development

Energy Technology Data Exchange (ETDEWEB)

Kang, Chul Hyung; Kuh, J. E.; Kim, S. K. and others

2000-04-01

Spent fuel inventories to be disposed of finally and design base spent fuel were determined. Technical and safety criteria for a geological repository system in Korea were established. Based on the properties of spent PWR and CANDU fuels, seven repository alternatives were developed and the most promising repository option was selected by the pair-wise comparison method from the technology point of view. With this option preliminary conceptual design studies were carried out. Several module, e.g., gap module, congruent release module were developed for the overall assessment code MASCOT-K. The prominent overseas databases such as OECD/NEA FEP list were are fully reviewed and then screened to identify the feasible ones to reflect the Korean geo-hydrological conditions. In addition to this the well known scenario development methods such as PID, RES were reviewed. To confirm the radiological safety of the proposed KAERI repository concept the preliminary PA was pursued. Thermo-hydro-mechanical analysis for the near field of repository were performed to verify thermal and mechanical stability for KAERI repository system. The requirements of buffer material were analyzed, and based on the results, the quantitative functional criteria for buffer material were established. The hydraulic and swelling property, mechanical properties, and thermal conductivity, the organic carbon content, and the evolution of pore water chemistry were investigated. Based on the results, the candidate buffer material was selected.

Geological disposal system development

International Nuclear Information System (INIS)

Kang, Chul Hyung; Kuh, J. E.; Kim, S. K. and others

2000-04-01

Spent fuel inventories to be disposed of finally and design base spent fuel were determined. Technical and safety criteria for a geological repository system in Korea were established. Based on the properties of spent PWR and CANDU fuels, seven repository alternatives were developed and the most promising repository option was selected by the pair-wise comparison method from the technology point of view. With this option preliminary conceptual design studies were carried out. Several module, e.g., gap module, congruent release module were developed for the overall assessment code MASCOT-K. The prominent overseas databases such as OECD/NEA FEP list were are fully reviewed and then screened to identify the feasible ones to reflect the Korean geo-hydrological conditions. In addition to this the well known scenario development methods such as PID, RES were reviewed. To confirm the radiological safety of the proposed KAERI repository concept the preliminary PA was pursued. Thermo-hydro-mechanical analysis for the near field of repository were performed to verify thermal and mechanical stability for KAERI repository system. The requirements of buffer material were analyzed, and based on the results, the quantitative functional criteria for buffer material were established. The hydraulic and swelling property, mechanical properties, and thermal conductivity, the organic carbon content, and the evolution of pore water chemistry were investigated. Based on the results, the candidate buffer material was selected

Acceptance-criteria for the bedrock for deep geologic disposal of spent nuclear fuel. Proceedings from a seminar at Gothenburg University

International Nuclear Information System (INIS)

1995-11-01

The seminar was directed to Nordic participants, and discussed disposal in the Nordic crystalline bedrock. Criteria for the bedrock should include: It should give durable mechanical protection for the engineered barriers; give a stable and favorable chemical environment for these barriers; have a low turnover of ground water in the near field; be easy to characterize; give favorable recipient-conditions; not have valuable minerals in workable quantities. These general criteria raise several questions coupled to the safety analysis: e.g. the need for geological, hydrological and geochemical parameters. Which data are missing, which are most difficult to find? What should the site characterization program look like to focus on factors that are of the highest importance according to the safety analysis. The demands on the conditions at a site need to be translated into quantitative criteria, which should be expressed as values that can be measured at the site or deduced from such measurements. These questions were discussed at the seminar, and 21 contributions from Finnish, Norwegian and Swedish participants are reported in these proceedings under the chapters: Coupling to the safety analysis; Methodology and criteria for site selection in a regional geoscientific perspective; Rock as a building material - prognosis and result; Geoscientific criteria for the bedrock at the repository - Mechanical protection; Geoscientific criteria for the bedrock at the repository - Low ground water turnover, chemically favorable and stable environment in the near field; Geoscientific criteria for the bedrock at the repository - Demands on the bedrock concerning the migration of radionuclides

Ultrasonographic screening for breast cancer using the recall criteria established by the Japan Association of Breast and Thyroid Sonology (JABTS)

International Nuclear Information System (INIS)

Tsukamoto, Noriko; Tsunoda-Shimizu, Hiroko; Kikuchi, Mari

2007-01-01

As is the case in many other countries, mammography is currently used in Japan for breast cancer screening. However, as it cannot detect lesions in dense breasts such as those of young women, ultrasound (US) imaging is used for this purpose. Although there have been numerous reports of US screening, the results obtained using the recall criteria stipulated by the Japan Association of Breast and Thyroid Sonology (JABTS) has not yet been reported. We have performed US screening based on the JABTS guidelines for three years. Technologists perform the examinations, and physicians select recall cases on the basis of these criteria. So far there have been 17,089 attendees, of whom 90% were less than 50 years old. The recall rate was 3.6% (616/17,089). The results of further examinations were confirmed in 452 of these 616 recalled women, and breast cancer was detected in 48 (0.28%) of them. Cancer was detected early in 37 (80.5%) of these 48 cases. Mammography was unable to detect cancer in 16 (43%) of the cases. Although the high recall rate of US screening has been mentioned previously, we wish to emphasize that US breast cancer screening is effective, particularly in younger women. Furthermore, the reasonable recall rate ensures that a high quality of detection is maintained. (author)

Research on geological disposal

Energy Technology Data Exchange (ETDEWEB)

NONE

2013-08-15

The aims of this research are to develop criteria for reviewing reliability and suitability of the result from Preliminary Investigations to be submitted by the implementer, and to establish a basic policy for safety review. For development of reliability and suitability criteria for reviewing the result of Preliminary Investigations, we evaluated the uncertainties and their influence from limited amount of investigations, as well as we identified important procedures during investigations and constructions of models, as follows: (1) uncertainties after limited amount of geological exploration and drilling, (2) influence of uncertainties in regional groundwater flow model, (3) uncertainties of DFN (Discrete Fracture Network) models in the fractured rock, (4) analyzed investigation methods described in implementer's report, and (5) identified important aspects in investigation which need to be reviewed and follow QA (Quality Assurance). For development of reliability and suitability criteria for reviewing the result of Detailed Investigations, we analyzed important aspects in investigation which supplies data to design and safety assessment, as well as studied the applicability of pressure interference data during excavation to verify hydrogeological model. Regarding the research for safety review, uncertainties of geologic process in long time-scale was studied. In FY2012, we started to evaluate the structural stabilities of concrete and bentonite in disposal environment. Finally, we continued to accumulate the knowledge on geological disposal into the database system. (author)

Geological disposal of radioactive waste. Safety requirements

International Nuclear Information System (INIS)

2006-01-01

This Safety Requirements publication is concerned with providing protection to people and the environment from the hazards associated with waste management activities related to disposal, i.e. hazards that could arise during the operating period and following closure. It sets out the protection objectives and criteria for geological disposal and establishes the requirements that must be met to ensure the safety of this disposal option, consistent with the established principles of safety for radioactive waste management. It is intended for use by those involved in radioactive waste management and in making decisions in relation to the development, operation and closure of geological disposal facilities, especially those concerned with the related regulatory aspects. This publication contains 1. Introduction; 2. Protection of human health and the environment; 3. The safety requirements for geological disposal; 4. Requirements for the development, operation and closure of geological disposal facilities; Appendix: Assurance of compliance with the safety objective and criteria; Annex I: Geological disposal and the principles of radioactive waste management; Annex II: Principles of radioactive waste management

Geological and geotechnical limitations of radioactive waste retrievability in geologic disposals

Energy Technology Data Exchange (ETDEWEB)

Stahlmann, Joachim; Leon-Vargas, Rocio; Mintzlaff, Volker; Treidler, Ann-Kathrin [TU Braunschweig (Germany). Inst. for Soil Mechanics and Foundation Engineering

2015-07-01

The capability of retrieving radioactive waste emplaced in deep geological formations is nowadays in discussion in many countries. Based on the storage of high-level radioactive waste (HAW) in deep geological repositories there is a number of possible scenarios for their retrieval. Measurements for an improved retrieving capability may impact on the geotechnical and geological barriers, e.g. keeping open the access drifts for a long period of time can result in a bigger evacuation damage zone (EDZ) in the host rock which implies potential flow paths for ground water. Nevertheless, to limit the possible scenarios associated to the retrieval implementation, it is necessary to take in consideration which criteria will be used for an efficient monitoring program, while clearly determining the performance reliability of the geotechnical barriers. In addition, the integrity of the host rock as geological barrier has to be verified. Therefore, it is important to evaluate different design solutions and the most appropriate measurement methods to improve the retrievability process of wastes from a geological repository. A short presentation of the host rocks is given is this paper.

Northeastern Regional geologic characterization report. Volume 1. Final report

International Nuclear Information System (INIS)

1985-08-01

This report presents available geologic information pertinent to siting a repository for high-level nuclear waste in crystalline rock in Connecticut, Maine, Massachusetts, New Hampshire, New Jersey, New York, Pennsylvania, Rhode Island, and Vermont. For each of the states within the Northeastern Region, information is provided on the geologic disqualifying factor and the geologic regional screening variables to be used in region-to-area screening. The geologic factor and variables include deep mines and quarries, rock mass extent, postemplacement faulting, suspected Quaternary faulting, seismicity, rock and mineral resources, major ground-water discharge zones, ground-water resources, state of stress, thickness of rock mass, and thickness of overburden. Information is presented on age, areal extent, shape, composition, texture, degree and type of alteration, thickness, and structural features associated with each rock body or complex. Regional seismic and tectonic information is presented, including patterns of earthquake occurrence, earthquake magnitudes, horizontal ground accelerations, and vertical crusal movements. Also included are discussions of the rock and mineral deposits or mines located within or near crystalline bodies; ground-water resources and regional hydrology; postulated changes in climate and the associated effects; and landforms, surface processes, and surficial materials on or near the rock bodies. A discussion is also presented on the relationship between the US Department of Energy (DOE) Siting Guidelines (10 CFR 960) and the geologic disqualifying factor and regional screening variables to be used in the region-to-area screening process

Repository operational criteria comparative analysis

International Nuclear Information System (INIS)

Hageman, J.P.; Chowdhury, A.H.

1994-06-01

The objective of the ''Repository Operational Criteria (ROC) Feasibility Studies'' (or ROC task) was to conduct comprehensive and integrated analyses of repository design, construction, and operations criteria in 10 CFR Part 60 regulations considering the interfaces among the components of the regulations and impacts of any potential changes to those regulations. The ROC task addresses regulatory criteria and uncertainties related to the preclosure aspects of the geologic repository. Those parts of 10 CFR Part 60 that require routine guidance or minor changes to the rule were addressed in Hageman and Chowdhury, 1992. The ROC task shows a possible need for further regulatory clarity, by major changes to the rule, related to the design bases and siting of a geologic repository operations area and radiological emergency planning in order to assure defense-in-depth. The analyses, presented in this report, resulted in the development and refinement of regulatory concepts and their supporting rationale for recommendations for potential major changes to 10 CFR Pan 0 regulations

A comparison of international criteria for the ultimate storage of radioactive wastes

International Nuclear Information System (INIS)

Mielke, H.

1985-01-01

In countries other than the Federal Republic of Germany and internationally there are no comprehensive codes referring to criteria and safety requirements except those of the IAEA and USA. In other countries there exist safety goals for the ultimate storage or for purely geological criteria. The degree of detailing regulations differs widely abroad and internationally. Safety goals abroad and internationally as well as measures for their realisation in the ultimate storage of radioactive wastes in deep geological formations are in line with the German safety goals. The IAEA refers to general aspects of geological, waste technology and ultimate storage technology criteria. In the USA, ultimate storage technology criteria have been quantified in part. The quantitative geological criteria existing in Great Britain and in the Netherlands are only relevant in as much as safety analyses must be performed for a specific site to provide evidence for the safety of this site. The comparison shows that most requirements pronounced abroad are also made for the Federal Republic of Germany. Some requirements are more specified in the Federal Republic of Germany, some are more detailed abroad. (orig./HP) [de

Marine cold seeps and their manifestations: geological control, biogeochemical criteria and environmental conditions

Science.gov (United States)

Suess, Erwin

2014-10-01

Characteristics of cold seeps at different geologic settings are the subject of this review primarily based on results of the Research Consortium SFB 574. Criteria are drawn from examples on the erosive convergent margin off Costa Rica, the accretionary margin off Chile supplemented by examples from the transform margin of the Golf of Cadiz and the convergent Hikurangi margin off New Zealand. Others are from well-studied passive margins of the Black Sea, the Golf of Mexico, the eastern Mediterranean Sea and the South China Sea. Seeps at all settings transport water and dissolved compounds to the ocean through the seafloor by different forcing mechanism and from different depths of the submerged geosphere (10s of meters to 10s of km). The compounds sustain oasis-type ecosystems by providing bioactive reductants sulfide, methane and hydrogen. Hereby, the interaction between fluid composition, flux rates and biota results in a diagnostic hydrocarbon-metazoan-microbe-carbonate association; currently, well over 100 active sites are known. The single most important reaction is microbially mediated anaerobic oxidation of methane with secondary reactions involving S-biogeochemistry and carbonate mineral precipitation. Seep fluids and their seafloor manifestations provide clues as to source depth, fluid-sediment/rock interaction during ascent, lifetime and cyclicity of seepage events but less so on the magnitude of return flow. At erosive margins, Cl-depleted and B-enriched fluids from clay dehydration provide criteria for source depth and temperature. The upward material flow generates mud volcanoes at the seafloor above the projected location of dehydration at depth. At accretionary margins, fluids are derived from more shallow depths by compaction of sediments as they ride on the incoming oceanic plate; they are emitted through thrust faults. At highly sedimented margins, organic-rich and evaporite-containing strata (when present) determine the final fluid composition

Common criteria among States for storage and use of dried blood spot specimens after newborn screening

Directory of Open Access Journals (Sweden)

Carlo Petrini

2012-06-01

Full Text Available Biological samples collected in biobanks are a resource with significant research potential. The Italian Joint Group cNB - cNBBSV (National committee of Bioethics - National committee for Biosecurity, Biotechnologies and Life Sciences published a document reporting recommendations on storage and use of dried blood spot (DBS and on the development of a National Network of Regional Newborn Screening Repositories for collection of residual DBS. Several ethical questions (about consent, possible use of genetic information, unanticipated possible usages for research purposes rise from residual newborn screening specimens collections. Moreover, legal and ethical controversies are accentuated by the conflicts between the interests of sample donors, biobank holders, researchers and the public. To overcome these difficulties the identification of a few criteria for storage and research usage of DBS is crucial.

North Central Regional geologic characterization report. Volume 1. Final report

International Nuclear Information System (INIS)

1985-08-01

This report presents available geologic information pertinent to siting a repository for high-level nuclear waste in crystalline rock in Minnesota, Wisconsin, and the Upper Peninsula of Michigan. For each of the states within the North Central Region, information is provided on the geologic disqualifying factor and the geologic regional screening variables to be used in region-to-area screening. The geologic factor and variables include deep mines and quarries, rock mass extent, post-emplacement faulting, suspected Quaternary faulting, seismicity, rock and mineral resources, major groundwater discharge zones, groundwater resources, state of stress, thickness of rock mass, and thickness of overburden. Information is presented on age, areal extent, shape, composition, texture, degree and type of alteration, thickness, and structural features associated with each rock body or complex. Regional seismic and tectonic information is presented, including patterns of earthquake occurrence, earthquake magnitudes, horizontal ground accelerations, and vertical crustal movements. Also included are discussions of the rock and mineral deposits or mines located within or near crystalline rock bodies; groundwater resources and regional hydrology; postulated changes in climate and the associated effects; and landforms, surface processes, and surficial materials on or near the rock bodies. A discussion is also presented of the relationship between the US Department of Energy Siting Guidelines (10 CFR 960) and the geologic disqualifying factor and regional screening variables to be used in the region-to-area screening process. 43 figs., 15 tabs

FMS Scores Change With Performers' Knowledge of the Grading Criteria-Are General Whole-Body Movement Screens Capturing "Dysfunction"?

Science.gov (United States)

Frost, David M; Beach, Tyson A C; Callaghan, Jack P; McGill, Stuart M

2015-11-01

Deficits in joint mobility and stability could certainly impact individuals' Functional Movement Screen (FMS) scores; however, it is also plausible that the movement patterns observed are influenced by the performers' knowledge of the grading criteria. Twenty-one firefighters volunteered to participate, and their FMS scores were graded before and immediately after receiving knowledge of the movement patterns required to achieve a perfect score on the FMS. Standardized verbal instructions were used to administer both screens, and the participants were not provided with any coaching or feedback. Time-synchronized sagittal and frontal plane videos were used to grade the FMS. The firefighters significantly (p injury risk.

The U.S. Geological Survey Geologic Collections Management System (GCMS)—A master catalog and collections management plan for U.S. Geological Survey geologic samples and sample collections

Science.gov (United States)

,

2015-01-01

The U.S. Geological Survey (USGS) is widely recognized in the earth science community as possessing extensive collections of earth materials collected by research personnel over the course of its history. In 2006, a Geologic Collections Inventory was conducted within the USGS Geology Discipline to determine the extent and nature of its sample collections, and in 2008, a working group was convened by the USGS National Geologic and Geophysical Data Preservation Program to examine ways in which these collections could be coordinated, cataloged, and made available to researchers both inside and outside the USGS. The charge to this working group was to evaluate the proposition of creating a Geologic Collections Management System (GCMS), a centralized database that would (1) identify all existing USGS geologic collections, regardless of size, (2) create a virtual link among the collections, and (3) provide a way for scientists and other researchers to obtain access to the samples and data in which they are interested. Additionally, the group was instructed to develop criteria for evaluating current collections and to establish an operating plan and set of standard practices for handling, identifying, and managing future sample collections. Policies and procedures promoted by the GCMS would be based on extant best practices established by the National Science Foundation and the Smithsonian Institution. The resulting report—USGS Circular 1410, “The U.S. Geological Survey Geologic Collections Management System (GCMS): A Master Catalog and Collections Management Plan for U.S. Geological Survey Geologic Samples and Sample Collections”—has been developed for sample repositories to be a guide to establishing common practices in the collection, retention, and disposal of geologic research materials throughout the USGS.

The basic principle and criteria for ore prospecting of uranium neutralizing-reduction mineralization

International Nuclear Information System (INIS)

Shi Weijun; Zhou Wenbin; Yuan Xiaoqin

1992-01-01

The author discuss the geological criteria, alternated mineral and geochemical criteria of field recognition which is beneficial to the uranium neutralizing-reduction mineralization sectors on the basis of brief introduction to the principle of uranium neutralizing-reduction mineralization, and the geological significance of uranium neutralizing-reduction mineralization is also stated

Geologic repositories for radioactive waste: the nuclear regulatory commission geologic comments on the environmental assessment

International Nuclear Information System (INIS)

Justus, P.S.; Trapp, J.S.; Westbrook, K.B.; Lee, R.; Blackford, M.B.; Rice, B.

1985-01-01

The NRC staff completed its review of the Environmental Assessments (EAs) issued by the Department of Energy (DOE) in December, 1984, in support of the site selection processes established by the Nuclear Waste Policy Act of 1982 (NWPA). The EAs contain geologic information on nine sites that DOE has identified as potentially acceptable for the first geologic repository in accordance with the requirements of NWPA. The media for the sites vary from basalt at Hanford, Washington, tuff at Yucca Mountain, Nevada, bedded salt in the Palo Duro Basin, Texas and Paradox Basin, Utah, to salt domes in Mississippi and Louisiana. Despite the diversity in media there are common areas of concern for all sites. These include; structural framework and pattern, rates of tectonic and seismic activity, characterization of subsurface features, and stratigraphic thickness, continuity and homogeneity. Site-specific geologic concerns include: potential volcanic and hydrothermal activity at Yucca Mountain, potential hydrocarbon targets and deep basalt and sub-basalt structure at Hanford, and potential dissolution at all salt sites. The NRC comments were influenced by the performance objectives and siting criteria of 10 CFR Part 60 and the environmental protection criteria in 40 CFR Part 191, the applicable standards proposed by EPA. In its review the NRC identified several areas of geologic concern that it recommended DOE re-examine to determine if alternative or modified conclusions are appropriate

Status and development of deep geological repository in Slovak republic from geological point of view

Directory of Open Access Journals (Sweden)

Jozef Franzen

2007-01-01

Full Text Available During the operation of Slovak NPPs, production of approximately 2,300 metric tons of spent fuel expressed as heavy metal (18,654 spent fuel assemblies is expected. In addition, about 5000 metric tons of radioactive waste unfit for near surface repository at Mochovce and destined for a deep geological disposal. The safe and long-term solution of back-end fuel cycle is so highly required.One of the most favorable solutions is Deep Geological Repository (DGR. The site for a DGR, along with repository design and the engineered barrier system must ensure long-term safety of the disposal system.A preliminary set of site-selection criteria for a DGR was proposed in Slovakia, based on worldwide experience and consistent with IAEA recommendations. Main groups of criteria are: 1 geological and tectonic stability of prospective sites; 2 appropriate characteristics of host rock (lithological homogeneity, suitable hydrogeological and geochemical conditions, favourable geotechnical setting, absence of mineral resources, etc.; 3 conflict of interests (natural resources, natural and cultural heritage, protected resources of thermal waters, etc..Based on the previous geological investigations, three distinct areas (five localities were determined as the most prospective sites for construction of a DGR so far. Three of them are built by granitoids rock (Tribeč Mts., Veporske vrchy Mts. and Stolicke vrchy Mts., other consist of sedimentary rock formations (Cerova vrchovina Upland and Rimavska kotlina Basin. Objective for the next investigation stage is to perform more detailed geological characterization of the prospective sites.

Geological history of uranium

International Nuclear Information System (INIS)

Niini, Heikki

1989-01-01

Uranium is widely distributed in continental geological environments. The order of magnitude of uranium abundance in felsitic igneous rocks is 2-15 ppm, whereas it is less than 1 ppm in mafic rocks. Sedimentary rocks show a large range: from less than 0.1 ppm U in certain evaporites to over 100 ppm in phosphate rocks and organogenic matter. The content of U in seawater varies from 0.0005 to 0.005 ppm. The isotopic ratio U-238/U-235 is presently 137.5+-0.5, having gradually increased during geological time. The third natural isotope is U-234. On the basis of three fundamental economic criteria for ore reserves assessment (geological assurance, technical feasibility, and the grade and quantity of the deposits), the author finally comes to the following conclusions: Although the global uranium ores are not geologically renewable but continuously mined, they still, due to exploration and technical development, will tend to progressively increase for centuries to come

Assessing rare earth elements in quartz rich geological samples.

Science.gov (United States)

Santoro, A; Thoss, V; Ribeiro Guevara, S; Urgast, D; Raab, A; Mastrolitti, S; Feldmann, J

2016-01-01

Sodium peroxide (Na2O2) fusion coupled to Inductively Coupled Plasma Tandem Mass Spectrometry (ICP-MS/MS) measurements was used to rapidly screen quartz-rich geological samples for rare earth element (REE) content. The method accuracy was checked with a geological reference material and Instrumental Neutron Activation Analysis (INAA) measurements. The used mass-mode combinations presented accurate results (only exception being (157)Gd in He gas mode) with recovery of the geological reference material QLO-1 between 80% and 98% (lower values for Lu, Nd and Sm) and in general comparable to INAA measurements. Low limits of detection for all elements were achieved, generally below 10 pg g(-1), as well as measurement repeatability below 15%. Overall, the Na2O2/ICP-MS/MS method proved to be a suitable lab-based method to quickly and accurately screen rock samples originating from quartz-rich geological areas for rare earth element content; particularly useful if checking commercial viability. Copyright © 2015 Elsevier Ltd. All rights reserved.

Geological investigations for the South African nuclear waste repository facility

International Nuclear Information System (INIS)

Hambleton-Jones, B.B.; Levin, M.; Andersen, N.J.B.; Brynard, H.J.; Toens, P.D.

1984-02-01

The selection of the Vaalputs site on the arid Bushmanland Plateau in the northwestern Cape of the Republic of South Africa for the disposal of low-level radioactive waste was based on a national screening phase program involving socio-economic and geological criteria. Regional geohydrological studies over an area of 27,000 km 2 and a detailed study over 1,300 km 2 indicated that in general the groundwater is saline and that Vaalputs and environs was the most favourable area. The groundwater table lies between 30 and 45 m below the surface, with 14 C ages between 2,500 and 9,000 years old in the immediate vicinity. The geology of Vaalputs consists of Proterozoic granites, gneisses, metasediments, and noritoids of the 1,050 Ma Namaqualand Metamorphic Complex. Upper cretaceous kimberlitic and basaltic intrusions occur locally. Overlying these basement rocks surficial upper Tertiary to Recent argillaceous sediments occur in the Vaalputs basin. The sediments consist of aeolian sand, calcrete, fluvial sandy to gritty clay, white kaolinised clay and very weathered basement rocks. It is in these rocks that the low-level waste trenches will be located. Extensive airborne geophysical surveys, such as aeromagnetics, INPUT, and infrared thermal line scanning, were undertaken to assist in the evaluation of the regional and local subsurface geology. Ground geophysical surveys included refraction seismics, electromagnetics, magnetics, borehole radiometrics and resistivity. Geohydrological modelling of the unsaturated and saturated zones is in progress

STOPP (Screening Tool of Older Persons' potentially inappropriate Prescriptions): application to acutely ill elderly patients and comparison with Beers' criteria.

LENUS (Irish Health Repository)

Gallagher, Paul

2012-02-03

Introduction: STOPP (Screening Tool of Older Persons\\' potentially inappropriate Prescriptions) is a new, systems-defined medicine review tool. We compared the performance of STOPP to that of established Beers\\' criteria in detecting potentially inappropriate medicines (PIMs) and related adverse drug events (ADEs) in older patients presenting for hospital admission. METHODS: we prospectively studied 715 consecutive acute admissions to a university teaching hospital. Diagnoses, reason for admission and concurrent medications were recorded. STOPP and Beers\\' criteria were applied. PIMs with clear causal connection or contribution to the principal reason for admission were determined. RESULTS: median patient age (interquartile range) was 77 (72-82) years. Median number of prescription medicines was 6 (range 0-21). STOPP identified 336 PIMs affecting 247 patients (35%), of whom one-third (n = 82) presented with an associated ADE. Beers\\' criteria identified 226 PIMs affecting 177 patients (25%), of whom 43 presented with an associated ADE. STOPP-related PIMs contributed to 11.5% of all admissions. Beers\\' criteria-related PIMs contributed to significantly fewer admissions (6%). CONCLUSION: STOPP criteria identified a significantly higher proportion of patients requiring hospitalisation as a result of PIM-related adverse events than Beers\\' criteria. This finding has significant implications for hospital geriatric practice.

Geological techniques used in the siting of South Africa's nuclear facilities

International Nuclear Information System (INIS)

Andersen, N.J.B.

1990-01-01

Nuclear site selection studies begin with an initial screening phase in order to pick regions which could be potentially suitable. When assessing a potential nuclear site from a structural geological point of view, the most important factors are the presence of 'capable faults', the seismicity of the area, and the existence of good foundation rock. A geological evaluation of a potential site involves a literature survey for all existing geological data on the site, geophysical investigations, structural domain analysis and geological mapping

Storage of radioactive wastes in geological formations. Technical criteria for site selection. Report by the work-group chaired by Professor Goguel

International Nuclear Information System (INIS)

Goguel, Jean; Candes, Pierre; Izabel, Cecile; Autran, Albert; Barthoux, Alain; Baudin, Guy; Devillers, Christian; Habib, Pierre; Lafuma, Jacques; Lefevre, Jean; Peaudecerf, Pierre; Pradel, Jacques; Salle, Claude; Treuil, Michel; Lebrun, Patrick; Tissier, Marie-Solange

1985-06-01

This document is the result of a prospective mission on the long term storage of radioactive wastes containing long-period emitters (wastes of B and C categories), and notably on a definitive storage in deep continental geological formations. After a presentation of hypotheses (brief description of the storage concept, main safety principles, objectives in terms of radiological safety, safety options, time-related considerations), the authors addressed the following issues: safety before closing during the exploitation period, and safety after closure (after backfilling and sealing of all underground cavities). For the first issue, they discuss the impacts of works on safety and thermal effects during exploitation. For the second issue, they discuss the site natural hydro-geological context, the disturbances brought by the storage (access of water to the storage, and return of water into the biosphere), and the influence of external factors (geological phenomena, human intrusion). Then, the authors make recommendations regarding reconnaissance programs and studies for the selection and qualification of a site. They finally propose technical criteria and main recommendations for site selection. Appendices propose a list of hearings, a presentation of the storage concept, a report on the impact of works, a report on the presence of mineralisation in granite massifs, reports on radiological consequences of intrusions in salt formations and in granite massif containing storage of radioactive wastes or vitrified wastes, a report on the characterization of unsteady parts of the French continental construction, a presentation of the evolution of climate and icings, and a study of seismic movements in the case of deep storages

Disposal of high level radioactive wastes in geological formations

International Nuclear Information System (INIS)

Martins, L.A.M.; Carvalho Bastos, J.P. de

1978-01-01

The disposal of high-activity radioactive wastes is the most serious problem for the nuclear industry. Among the solutions, the disposal of wastes in approriated geological formations is the most realistic and feasible. In this work the methods used for geological disposal, as well as, the criteria, programs and analysis for selecting a bite for waste disposal are presented [pt

Studies of the suitability of salt domes in east Texas basin for geologic isolation of nuclear wastes

International Nuclear Information System (INIS)

Kreitler, C.W.

1979-01-01

The suitability of salt domes in the east Texas basin (Tyler basin), Texas, for long-term isolation of nulear wastes is being evaluated. The major issues concern hydrogeologic and tectonic stability of the domes and potential natural resources in the basin. These issues are being approached by integration of dome-specific and regional hydrogeolgic, geologic, geomorphic, and remote-sensing investigations. Hydrogeologic studies are evaluating basinal hydrogeology and ground-water flow around the domes in order to determine the degree to which salt domes may be dissolving, their rates of solution, and the orientation of saline plumes in the fresh-water aquifers. Subsurface geologic studies are being conducted: (1) to determine the size and shape of specific salt domes, the geology of the strata immediately surrounding the domes, and the regional geology of the east Texas basin; (2) to understand the geologic history of dome growth and basin infilling; and (3) to evaluate potential natural resources. Geomorphic and surficial geology studies are determining whether there has been any dome growth or tectonic movement in the basin during the Quaternary. Remote-sensing studies are being conducted to determine: (1) if dome uplift has altered regional lineation patterns in Quaternary sediments; and (2) whether drainage density indicates Quaternary structural movement. On the basis of the screening criteria of Brunton et al (1978), Oakwood and Keechi domes have been chosen as possible candidate domes. Twenty-three domes have been eliminated because of insufficient size, too great a depth to salt, major hydrocarbon production, or previous use (such as liquid propane storage or salt mining or brining). Detailed geologic, hydrogeologic, and geomorphic investigations are now being conducted around Oakwood and Keechi salt domes

Geological aspects of radioactive waste disposal

International Nuclear Information System (INIS)

Kobera, P.

1985-01-01

Geological formations suitable for burying various types of radioactive wastes are characterized applying criteria for the evaluation and selection of geological formations for building disposal sites for radioactive wastes issued in IAEA technical recommendations. They are surface disposal sites, disposal sites in medium depths and deep disposal sites. Attention is focused on geological formations usable for injecting self-hardening mixtures into cracks prepared by hydraulic decomposition and for injecting liquid radioactive wastes into permeable rocks. Briefly outlined are current trends of the disposal of radioactive wastes in Czechoslovakia and the possibilities are assessed from the geological point of view of building disposal sites for radioactive wastes on the sites of Czechoslovak nuclear power plants at Jaslovske Bohunice, Mochovce, Dukovany, Temelin, Holice (eastern Bohemia), Blahoutovice (northern Moravia) and Zehna (eastern Slovakia). It is stated that in order to design an optimal method of the burial of radioactive waste it will be necessary to improve knowledge of geological conditions in the potential disposal sites at the said nuclear plants. There is usually no detailed knowledge of geological and hydrological conditions at greater depths than 100 m. (Z.M.)

NWTS program criteria for mined geologic disposal of nuclear waste: program objectives, functional requirements, and system performance criteria

International Nuclear Information System (INIS)

1981-04-01

At the present time, final repository criteria have not been issued by the responsible agencies. This document describes general objectives, requirements, and criteria that the DOE intends to apply in the interim to the National Waste Terminal Storage (NWTS) Program. These objectives, requirements, and criteria have been developed on the basis of DOE's analysis of what is needed to achieve the National objective of safe waste disposal in an environmentally acceptable and economic manner and are expected to be consistent with anticipated regulatory standards. The qualitative statements in this document address the broad issues of public and occupational health and safety, institutional acceptability, engineering feasibility, and economic considerations. A comprehensive set of criteria, general and project specific, of which these are a part, will constitute a portion of the technical basis for preparation and submittal by the DOE of formal documents to support future license applications for nuclear waste repositories

NWTS program criteria for mined geologic disposal of nuclear waste: program objectives, functional requirements, and system performance criteria

Energy Technology Data Exchange (ETDEWEB)

None

1981-04-01

At the present time, final repository criteria have not been issued by the responsible agencies. This document describes general objectives, requirements, and criteria that the DOE intends to apply in the interim to the National Waste Terminal Storage (NWTS) Program. These objectives, requirements, and criteria have been developed on the basis of DOE's analysis of what is needed to achieve the National objective of safe waste disposal in an environmentally acceptable and economic manner and are expected to be consistent with anticipated regulatory standards. The qualitative statements in this document address the broad issues of public and occupational health and safety, institutional acceptability, engineering feasibility, and economic considerations. A comprehensive set of criteria, general and project specific, of which these are a part, will constitute a portion of the technical basis for preparation and submittal by the DOE of formal documents to support future license applications for nuclear waste repositories.

Southeastern Regional geologic characterization report. Volume 1. Final report

International Nuclear Information System (INIS)

1985-08-01

This report presents available geologic information pertinent to siting a repository for high-level nuclear waste in crystalline rock in central Maryland; noncoastal Virginia, North Carolina, and South Carolina; and northern Georgia. For each of the states within the Southeastern Region, information is provided on the geological disqualifying factor and the geologic regional screening variables to be used in region-to-area screening. The geological factor and variables include deep mines and quarries, rock mass extent, postemplacement faulting, suspected Quaternary faulting, seismicity, rock and mineral resources, major ground-water discharge zones, ground-water resources, state of stress, thickness of rock mass, and thickness of overburden. Information is presented on the age, areal extent, shape, composition, texture, degree and type of alteration, thickness, and structural features associated with each rock body or complex. Regional seismic and tectonic information is presented, including patterns of earthquake occurrence, earthquake magnitudes, horizontal ground accelerations, and vertical crustal movements. Also included are discussions of the rock and mineral deposits or mines located within or near crystalline bodies; ground-water resources and regional hydrology; postulated changes in climate and the associated effects; and landforms, surface processes, and surficial materials on or near the rock bodies

Final disposal of radioactive wastes. Site selection criteria. Technical and economical factors

International Nuclear Information System (INIS)

Granero, J.J.

1984-01-01

General considerations, geological and socioeconomical criteria for final disposal of radioactive wastes in geological formations are treated. More attention is given to the final disposal of high level radioactive wastes and different solutions searched abroad which seems of interest for Spain. (author)

Utilization of International Association of Diabetes and Pregnancy Study Groups criteria vs. a two-step approach to screening for gestational diabetes mellitus in Chinese women with twin pregnancies.

Science.gov (United States)

Liu, X; Chen, Y; Zhou, Q; Shi, H; Cheng, W W

2015-03-01

To evaluate prevalence and pregnancy outcomes using the International Association of Diabetes and Pregnancy Study Groups (IADPSG) criteria and screening protocol vs. a standard two-step screening approach for gestational diabetes mellitus in Chinese twin pregnancies. A retrospective cohort study for pregnancies during 2007-2013 was performed in a tertiary hospital in Shanghai, China. Data were abstracted from the medical records of twin pregnancies delivered at the hospital. During the period 2007-2011, this hospital used a two-step approach with a 50 g screening with a cut-off value of ≥ 7.8 mmol/l followed by a 100 g diagnostic oral glucose tolerance test (OGTT) utilizing Carpenter-Coustan criteria. In 2012-2013, the hospital switched to the IADPSG protocol of universal 75 g OGTT. Among 1461 twin pregnancies, 643 were screened utilizing IADPSG criteria and 818 using the two-step protocol. Gestational diabetes mellitus was diagnosed more frequently in the IADPSG group than in the two-step group [20.4% and 7.0%, respectively; adjusted odds ratio (aOR) = 3.22; 95% confidence interval (CI) = 2.30-4.52]. During the IADPSG period, the incidence of pre-eclampsia was 38% lower in non-gestational diabetes mellitus affected pregnancies compared with the two-step period (aOR = 0.62; 95% CI = 0.44-0.87). We observed no significant differences in most perinatal outcomes between the two groups. Compared with a standard two-step approach to screening and diagnosis, the IADPSG screening method resulted in a three-fold increase in the incidence of gestational diabetes mellitus in twin pregnancies, with a 38% lower risk of pre-eclampsia but no significant difference in most perinatal outcomes in non-gestational diabetes mellitus affected pregnancies. © 2014 The Authors. Diabetic Medicine © 2014 Diabetes UK.

10 CFR 63.161 - Emergency plan for the geologic repository operations area through permanent closure.

Science.gov (United States)

2010-01-01

... Planning Criteria § 63.161 Emergency plan for the geologic repository operations area through permanent... 10 Energy 2 2010-01-01 2010-01-01 false Emergency plan for the geologic repository operations area... may occur at the geologic repository operations area, at any time before permanent closure and...

Rethinking of the criteria for natural analogue study. A case of Tono natural analogue study

International Nuclear Information System (INIS)

Yoshida, Hidekazu

1996-01-01

Natural analogue regarding long-term performance of the geological disposal system for radioactive waste isolation is essentially the study of geochemical process which has been evolved in geological environment. All geochemical studies, however, will not be nominated as natural analogue studies. It is, therefore, important to be clear the criteria for natural analogue study with the view of analogy by following three categories, (1) Conceptual model development, (2) Data provision and (3) Model testing, for the concept of geological disposal and safety assessment model. Rethinking of the criteria for natural analogue study through the case of Tono Natural Analogue Study, and the usefulness of natural analogue study for the safety assessment of geological disposal system in Japan have been presented in this paper. (author)

[Inappropriate prescription in older patients: the STOPP/START criteria].

LENUS (Irish Health Repository)

Delgado Silveira, Eva

2009-09-01

Older people are a heterogeneous group of patients, often with multiple comorbidities for which they are prescribed a large number of drugs, leading to an increased risk of adverse drug reactions (ADR) and drug interactions. This risk is compounded by physiological age-related changes in physiology, changes in drug pharmacokinetics and pharmacodynamics, as well as by disease-related, functional and social issues. Inappropriate prescription of drugs is common in the older individuals and contributes to the increased risk of ADR. Several tools have been developed to detect potentially inappropriate prescription, the most frequently used in Spain being Beers\\' criteria. However, the value of these criteria is limited, especially as they were developed in a different healthcare system. In this article, the Spanish version of a new tool to detect potentially inappropriate prescriptions-STOPP (Screening Tool of Older Person\\'s Prescriptions) and START (Screening Tool to Alert doctors to Right i.e. appropriate, indicated Treatment) criteria-is presented. The creation, development, reliability, and use of these criteria in routine practice is described and discussed. These criteria have shown better sensitivity than Beers\\' criteria in detecting prescription problems and have the added value of being able to detect not only inappropriate prescription of some drugs, but also the omission of well indicated drugs. The STOPP\\/START criteria could become a useful screening tool to improve prescription in older people.

Clinically targeted screening for congenital CMV - potential for integration into the National Hearing Screening Programme.

Science.gov (United States)

Kadambari, S; Luck, S; Davis, A; Williams, Ej; Berrington, J; Griffiths, Pd; Sharland, M

2013-10-01

Screening for a condition should only be undertaken if certain strict criteria are met. Congenital CMV (cCMV) is a leading cause of sensorineuronal hearing loss (SNHL) and meets many of these criteria, but is not currently screened for in the UK. Ganciclovir reduces CMV-induced progressive SNHL if treatment is begun in the first month of life. The Newborn Hearing Screening Programme (NHSP) has been shown to identify SNHL at the earliest possible age. The potential of integrating screening for cCMV into the NHSP is discussed to consolidate the link between screening, early diagnosis and management. The early diagnosis and treatment of cCMV may prevent a small proportion of late SNHL. In the absence of any screening programme, we provide evidence that clinically targeted screening through the NHSP is a potential option in the UK, enhancing the diagnostic pathway and enabling appropriate early treatment to reduce long-term morbidity. ©2013 Foundation Acta Paediatrica. Published by John Wiley & Sons Ltd.

GIS-technologies as a mechanism to study geological structures

Science.gov (United States)

Sharapatov, Abish

2014-05-01

Specialized GIS-technologies allow creating multi-parameter models, completing multi-criteria optimisation tasks, and issues of geological profile forecasts using miscellaneous data. Pictorial and attributive geological and geophysical information collected to create GIS database is supplemented by the ERS (Earth's Remote Sensing) data, air spectrometry, space images, and topographic data. Among the important tasks are as follows: a unification of initial geological, geophysical and other types of information on a tectonic position, rock classification and stratigraphic scale; topographic bases (various projectures, scales); the levels of detail and exhaustibility; colors and symbols of legends; data structures and their correlation; units of measurement of physical quantities, and attribute systems of descriptions. Methods of the geological environment investigation using GIS-technology are based on a principle of the research target analogy with a standard. A similarity ratio is quantitative estimate. A geological forecast model is formed by structuring of geological information based on detailed analysis and aggregation of geological and formal knowledge bases on standard targets. Development of a bank of models of the analyzed geological structures of various range, ore-bearing features described by numerous prospecting indicators is the way to aggregate geological knowledge. The south terrain of the Valerianovskaya structure-facies zone (SFZ) of the Torgai paleo-rift structure covered with thick Mesozoic and Cenozoic rocks up to 2,000m is considered a so-called training ground for the development of GIS-technology. Parameters of known magnetite deposits located in the north of the SFZ (Sarybaiskoye, Sokolovskoye, etc.) are used to create the standard model. A meaning of the job implemented involves the following: - A goal-seeking nature of the research being performed and integration of the geological, geo-physical and other data (in many cases, efforts of the

Interval lung cancer after a negative CT screening examination: CT findings and outcomes in National Lung Screening Trial participants

International Nuclear Information System (INIS)

Gierada, David S.; Pinsky, Paul F.; Duan, Fenghai; Garg, Kavita; Hart, Eric M.; Kazerooni, Ella A.; Nath, Hrudaya; Watts, Jubal R.; Aberle, Denise R.

2017-01-01

This study retrospectively analyses the screening CT examinations and outcomes of the National Lung Screening Trial (NLST) participants who had interval lung cancer diagnosed within 1 year after a negative CT screen and before the next annual screen. The screening CTs of all 44 participants diagnosed with interval lung cancer (cases) were matched with negative CT screens of participants who did not develop lung cancer (controls). A majority consensus process was used to classify each CT screen as positive or negative according to the NLST criteria and to estimate the likelihood that any abnormalities detected retrospectively were due to lung cancer. By retrospective review, 40/44 cases (91%) and 17/44 controls (39%) met the NLST criteria for a positive screen (P < 0.001). Cases had higher estimated likelihood of lung cancer (P < 0.001). Abnormalities included pulmonary nodules ≥4 mm (n = 16), mediastinal (n = 8) and hilar (n = 6) masses, and bronchial lesions (n = 6). Cancers were stage III or IV at diagnosis in 32/44 cases (73%); 37/44 patients (84%) died of lung cancer, compared to 225/649 (35%) for all screen-detected cancers (P < 0.0001). Most cases met the NLST criteria for a positive screen. Awareness of missed abnormalities and interpretation errors may aid lung cancer identification in CT screening. (orig.)

Interval lung cancer after a negative CT screening examination: CT findings and outcomes in National Lung Screening Trial participants

Energy Technology Data Exchange (ETDEWEB)

Gierada, David S. [Washington University School of Medicine, Mallinckrodt Institute of Radiology, Box 8131, St. Louis, MO (United States); Pinsky, Paul F. [National Cancer Institute, Bethesda, MD (United States); Duan, Fenghai [Brown University School of Public Health, Department of Biostatistics and Center for Statistical Sciences, Providence, RI (United States); Garg, Kavita [University of Colorado School of Medicine, Mail Stop F726, Box 6510, Aurora, CO (United States); Hart, Eric M. [Northwestern University, Feinberg School of Medicine, Department of Radiology, Chicago, IL (United States); Kazerooni, Ella A. [University of Michigan Health System, Department of Radiology, Ann Arbor, MI (United States); Nath, Hrudaya; Watts, Jubal R. [University of Alabama at Birmingham School of Medicine, Department of Radiology-JTN370, Birmingham, AL (United States); Aberle, Denise R. [David Geffen School of Medicine at UCLA, Department of Radiological Sciences, Los Angeles, CA (United States)

2017-08-15

This study retrospectively analyses the screening CT examinations and outcomes of the National Lung Screening Trial (NLST) participants who had interval lung cancer diagnosed within 1 year after a negative CT screen and before the next annual screen. The screening CTs of all 44 participants diagnosed with interval lung cancer (cases) were matched with negative CT screens of participants who did not develop lung cancer (controls). A majority consensus process was used to classify each CT screen as positive or negative according to the NLST criteria and to estimate the likelihood that any abnormalities detected retrospectively were due to lung cancer. By retrospective review, 40/44 cases (91%) and 17/44 controls (39%) met the NLST criteria for a positive screen (P < 0.001). Cases had higher estimated likelihood of lung cancer (P < 0.001). Abnormalities included pulmonary nodules ≥4 mm (n = 16), mediastinal (n = 8) and hilar (n = 6) masses, and bronchial lesions (n = 6). Cancers were stage III or IV at diagnosis in 32/44 cases (73%); 37/44 patients (84%) died of lung cancer, compared to 225/649 (35%) for all screen-detected cancers (P < 0.0001). Most cases met the NLST criteria for a positive screen. Awareness of missed abnormalities and interpretation errors may aid lung cancer identification in CT screening. (orig.)

Effectiveness of an annular closure device in a "real-world" population: stratification of registry data using screening criteria from a randomized controlled trial.

Science.gov (United States)

Kuršumović, Adisa; Rath, Stefan A

2018-01-01

Increased focus has been put on the use of "'real-world" data to support randomized clinical trial (RCT) evidence for clinical decision-making. The objective of this study was to assess the performance of an annular closure device (ACD) after stratifying a consecutive series of "real-world" patients by the screening criteria of an ongoing RCT. This was a single-center registry analysis of 164 subjects who underwent limited discectomy combined with ACD for symptomatic lumbar disc herniation. Patients were stratified into two groups using the selection criteria of a pivotal RCT on the same device: Trial (met inclusion; n=44) or non-Trial (did not meet inclusion; n=120). Patient-reported outcomes, including Oswestry Disability Index (ODI) and visual analog scale (VAS) for leg and back pain, and adverse events were collected from baseline to last follow-up (mean: Trial - 15.6 months; non-Trial - 14.6 months). Statistical analyses were performed with significance set at p population. Stratification of this "real-world" series on the basis of RCT screening criteria did not result in significant between-group differences. These findings suggest that the efficacy of the ACD extends beyond the strictly defined patient population being studied in the RCT of this device. Furthermore, reducing the reherniation rate following lumbar discectomy has positive clinical and economic implications.

The need for the geologic hazard analysis

International Nuclear Information System (INIS)

Mingarro, E.

1984-01-01

The parameters which are considered in the hazard analysis associated with the movements of the Earth Crust are considered. These movements are classified as: fast movements or seismic movements, which are produced in a certain geologic moment at a speed measured in cm/sg, and slow movements or secular movements, which take place within a long span of time at a speed measured by cm/year. The relations space/time are established after Poisson and Gumbel's probabilistic models. Their application is analyzed according to the structural gradient fields, which fall within Matteron's geostatistics studies. These statistic criteria should be analyzed or checked up in each geo-tectonic environment. This allows the definition of neotectonic and seismogenetic zones, because it is only in these zones where the probabilistic or deterministic criteria can be applied to evaluate the hazard and vulnerability, that is, to know the geologic hazard of every ''Uniform'' piece of the Earth Crust. (author)

Preliminary geologic site selection factors for the National Waste Terminal Storage Program

International Nuclear Information System (INIS)

1977-06-01

The geologic considerations and the associated factors that have to be addressed in the selection of repository sites in deep geologic formations are listed and described. In addition a description is given of the information necessary to assess the geologic factors. The methods of obtaining this information are described. An illustration is given of a general approach of how the geologic factors could be applied and integrated to assess the acceptability of candidate sites. No consideration is given to a detailed description of the application of integration of the geologic factors. The criteria associated with each factor that will be used are not defined

Program criteria for subseabed disposal of radioactive waste: research strategies and review processes

International Nuclear Information System (INIS)

1981-09-01

The Subseabed Disposal Program follows the policies and criteria of the National Waste Terminal Storage program for the development of land-based repositories, except where the technical differences between land and ocean geologic disposal make different approaches or criteria necessary. This is the first of a series of documents describing the procedures and criteria for the Subseabed Disposal Program

Do Lung Cancer Eligibility Criteria Align with Risk among Blacks and Hispanics?

Directory of Open Access Journals (Sweden)

Kevin Fiscella

Full Text Available Black patients have higher lung cancer risk despite lower pack years of smoking. We assessed lung cancer risk by race, ethnicity, and sex among a nationally representative population eligible for lung cancer screening based on Medicare criteria.We used data from the National Health and Nutrition Examination Survey, 2007-2012 to assess lung cancer risk by sex, race and ethnicity among persons satisfying Medicare age and pack-year smoking eligibility criteria for lung cancer screening. We assessed Medicare eligibility based on age (55-77 years and pack-years (≥ 30. We assessed 6-year lung cancer risk using a risk prediction model from Prostate, Lung, Colorectal and Ovarian Cancer Screening trial that was modified in 2012 (PLCOm2012. We compared the proportions of eligible persons by sex, race and ethnicity using Medicare criteria with a risk cut-point that was adjusted to achieve comparable total number of persons eligible for screening.Among the 29.7 million persons aged 55-77 years who ever smoked, we found that 7.3 million (24.5% were eligible for lung cancer screening under Medicare criteria. Among those eligible, Blacks had statistically significant higher (4.4% and Hispanics lower lung cancer risk (1.2% than non-Hispanic Whites (3.2%. At a cut-point of 2.12% risk for lung screening eligibility, the percentage of Blacks and Hispanics showed statistically significant changes. Blacks eligible rose by 48% and Hispanics eligible declined by 63%. Black men and Hispanic women were affected the most. There was little change in eligibility among Whites.Medicare eligibility criteria for lung cancer screening do not align with estimated risk for lung cancer among Blacks and Hispanics. Data are urgently needed to determine whether use of risk-based eligibility screening improves lung cancer outcomes among minority patients.

Assessing rare earth elements in quartz rich geological samples

International Nuclear Information System (INIS)

Santoro, A.; Thoss, V.; Ribeiro Guevara, S.; Urgast, D.; Raab, A.; Mastrolitti, S.; Feldmann, J.

2016-01-01

Sodium peroxide (Na_2O_2) fusion coupled to Inductively Coupled Plasma Tandem Mass Spectrometry (ICP-MS/MS) measurements was used to rapidly screen quartz-rich geological samples for rare earth element (REE) content. The method accuracy was checked with a geological reference material and Instrumental Neutron Activation Analysis (INAA) measurements. The used mass-mode combinations presented accurate results (only exception being "1"5"7Gd in He gas mode) with recovery of the geological reference material QLO-1 between 80% and 98% (lower values for Lu, Nd and Sm) and in general comparable to INAA measurements. Low limits of detection for all elements were achieved, generally below 10 pg g"−"1, as well as measurement repeatability below 15%. Overall, the Na_2O_2/ICP-MS/MS method proved to be a suitable lab-based method to quickly and accurately screen rock samples originating from quartz-rich geological areas for rare earth element content; particularly useful if checking commercial viability. - Highlights: • Na_2O_2 fusion coupled to ICP-MS/MS was used to determine REE in quartz-rich samples. • The method accuracy was checked with a geological reference material and INAA. • Results were within 80–98% recovery of QLO-1 reference material, comparable to INAA. • Detection limits were generally below 10 pg g"−"1, and repeatability was below 15%. • Na_2O_2/ICP-MS/MS proved to be a suitable method for REE in quartz-rich samples.

Validation of a French version of the Sleep Condition Indicator: a clinical screening tool for insomnia disorder according to DSM-5 criteria.

Science.gov (United States)

Bayard, Sophie; Lebrun, Cindy; Maudarbocus, Khaalid Hassan; Schellaert, Vanessa; Joffre, Alicia; Ferrante, Esther; Le Louedec, Marie; Cournoulat, Alice; Gely-Nargeot, Marie-Christine; Luik, Annemarie I

2017-12-01

Insomnia disorder is frequent in the population, yet there is no French screening instrument available that is based on the updated DSM-5 criteria. We evaluated the validity and reliability of the French version of an insomnia screening instrument based on DSM-5 criteria, the Sleep Condition Indicator, in a population-based sample of adults. A total of 366 community-dwelling participants completed a face-to-face clinical interview to determine insomnia disorder against DSM-5 criteria and several questionnaires including the French Sleep Condition Indicator version. Three-hundred and twenty-nine participants completed the Sleep Condition Indicator again after 1 month. Statistical analyses were performed to determine the reliability, construct validity, divergent validity and temporal stability of the French translation of the Sleep Condition Indicator. In addition, an explanatory factor analysis was performed to assess the underlying structure. The internal consistency (α = 0.87) and temporal stability (r = 0.86, P French Sleep Condition Indicator were high. When using the previously defined cut-off value of ≤ 16, the area under the receiver operating characteristic curve was 0.93 with a sensitivity of 95% and a specificity of 75%. Additionally, good construct and divergent validity were demonstrated. The factor analyses showed a two-factor structure with a focus on sleep and daytime effects. The French version of the Sleep Condition Indicator demonstrates satisfactory psychometric properties while being a useful instrument in detecting cases of insomnia disorder, consistent with features of DSM-5, in the general population. © 2017 European Sleep Research Society.

Performance of Clinical Criteria for Screening of Possible Antiretroviral Related Mitochondrial Toxicity in HIV-Infected Children in Accra.

Science.gov (United States)

Langs-Barlow, Allison; Renner, Lorna; Katz, Karol; Northrup, Veronika; Paintsil, Elijah

2013-01-01

Mitochondrial damage is implicated in highly active antiretroviral therapy (HAART) toxicity. HIV infection also causes mitochondrial toxicity (MT). Differentiating between the two is critical for HIV management. Our objective was to test the utility of the Mitochondrial Disease Criteria (MDC) and the Enquête Périnatale Française (EPF) to screen for possible HAART related MT in HIV-infected children in Ghana. The EPF and MDC are compilations of clinical symptoms, or criteria, of MT: a (+) score indicates possible MT. We applied these criteria retrospectively to 403 charts of HIV-infected children. Of those studied, 331/403 received HAART. Comparing HAART exposed and HAART naïve children, the difference in EPF score, but not MDC, approached significance (P = 0.1). Young age at HIV diagnosis or at HAART initiation was associated with (+) EPF (P ≤ 0.01). Adherence to HAART trended toward an association with (+) EPF (P = 0.09). Exposure to nevirapine, abacavir, or didanosine increased risk of (+) EPF (OR = 3.55 (CI = 1.99-6.33), 4.76 (2.39-9.43), 4.93 (1.29-18.87)). Neither EPF nor MDC identified a significant difference between HAART exposed or naïve children regarding possible MT. However, as indicators of HAART exposure are associated with (+) EPF, it may be a candidate for prospective study of possible HAART related MT in resource-poor settings.

Performance of Clinical Criteria for Screening of Possible Antiretroviral Related Mitochondrial Toxicity in HIV-Infected Children in Accra

Directory of Open Access Journals (Sweden)

Allison Langs-Barlow

2013-01-01

Full Text Available Mitochondrial damage is implicated in highly active antiretroviral therapy (HAART toxicity. HIV infection also causes mitochondrial toxicity (MT. Differentiating between the two is critical for HIV management. Our objective was to test the utility of the Mitochondrial Disease Criteria (MDC and the Enquête Périnatale Française (EPF to screen for possible HAART related MT in HIV-infected children in Ghana. The EPF and MDC are compilations of clinical symptoms, or criteria, of MT: a (+ score indicates possible MT. We applied these criteria retrospectively to 403 charts of HIV-infected children. Of those studied, 331/403 received HAART. Comparing HAART exposed and HAART naïve children, the difference in EPF score, but not MDC, approached significance (. Young age at HIV diagnosis or at HAART initiation was associated with (+ EPF (. Adherence to HAART trended toward an association with (+ EPF (. Exposure to nevirapine, abacavir, or didanosine increased risk of (+ EPF (OR = 3.55 (CI = 1.99–6.33, 4.76 (2.39–9.43, 4.93 (1.29–18.87. Neither EPF nor MDC identified a significant difference between HAART exposed or naïve children regarding possible MT. However, as indicators of HAART exposure are associated with (+ EPF, it may be a candidate for prospective study of possible HAART related MT in resource-poor settings.

Preliminary discussion on the application of the geological conceptual model method of uranium ore formation

International Nuclear Information System (INIS)

Ma Guangzhong; Wei Mingji; Luo Yiyue

1992-01-01

The geological conceptual model method of uranium ore formation is established on the basis of geological theory and apriorism. Variables are screened with the application of the method of mathematical geology to find out the variables which are more contributed. In combination with the practical situation in Xikang-Yunnan axis, the variables are compiled and graded so as to determine the optimal ore-controlling factor and to establish the statistical predictive model which is of geological significance. The resources evaluation work has been conducted in the Late Proterozoic geological terrain in Xikang-Yunnan axis

Strategies in screening for colon carcinoma

NARCIS (Netherlands)

de Wijkerslooth, T. R.; Bossuyt, P. M.; Dekker, E.

2011-01-01

Colorectal cancer is the second most common cancer in Europe and meets the criteria for population screening. Population screening should lead to a reduction in CRC-related mortality and incidence. Several options are available for CRC screening, which can be itemised as stool-based tests and

Nutrition screening tools: an analysis of the evidence.

Science.gov (United States)

Skipper, Annalynn; Ferguson, Maree; Thompson, Kyle; Castellanos, Victoria H; Porcari, Judy

2012-05-01

In response to questions about tools for nutrition screening, an evidence analysis project was developed to identify the most valid and reliable nutrition screening tools for use in acute care and hospital-based ambulatory care settings. An oversight group defined nutrition screening and literature search criteria. A trained analyst conducted structured searches of the literature for studies of nutrition screening tools according to predetermined criteria. Eleven nutrition screening tools designed to detect undernutrition in patients in acute care and hospital-based ambulatory care were identified. Trained analysts evaluated articles for quality using criteria specified by the American Dietetic Association's Evidence Analysis Library. Members of the oversight group assigned quality grades to the tools based on the quality of the supporting evidence, including reliability and validity data. One tool, the NRS-2002, received a grade I, and 4 tools-the Simple Two-Part Tool, the Mini-Nutritional Assessment-Short Form (MNA-SF), the Malnutrition Screening Tool (MST), and Malnutrition Universal Screening Tool (MUST)-received a grade II. The MST was the only tool shown to be both valid and reliable for identifying undernutrition in the settings studied. Thus, validated nutrition screening tools that are simple and easy to use are available for application in acute care and hospital-based ambulatory care settings.

Genetic screening and democracy: lessons from debating genetic screening criteria in the Netherlands

NARCIS (Netherlands)

van El, C.G.; Pieters, T.; Cornel, M.C.

2012-01-01

Recent decades have witnessed increasing possibilities for genetic testing and screening. In clinical genetics, the doctor's office defined a secluded space for discussion of sensitive reproductive options in cases of elevated risk for genetic disorders in individuals or their offspring. When

Impact of acute geriatric care in elderly patients according to the Screening Tool of Older Persons' Prescriptions/Screening Tool to Alert doctors to Right Treatment criteria in northern France.

Science.gov (United States)

Frély, Anne; Chazard, Emmanuel; Pansu, Aymeric; Beuscart, Jean-Baptiste; Puisieux, François

2016-02-01

In France, over 20% of hospitalizations of elderly people are a result of adverse drug events, of which 50% are considered preventable. Tools have been developed to detect inappropriate prescriptions. The Screening Tool of Older Persons' Prescriptions/Screening Tool to Alert doctors to Right Treatment (STOPP/START) criteria are innovative and adapted to French prescriptions. This is one of the first French prospective studies to evaluate the impact of acute geriatric care on prescriptions at discharge in elderly patients using the STOPP/START criteria. The evaluation of prescriptions according to STOPP/START was carried out on admission and at discharge of patients in acute geriatric units at three hospitals in the Nord-Pas de Calais region, France. A total of 202 elderly hospitalized patients were included during the 4.5 months of the study (1.5 months per center). The mean number of drugs was seven on admission and at discharge. Over half of the prescriptions at admission contained at least one potentially inappropriate medication or one potential prescription omission. The prescriptions at discharge contained significantly fewer potentially inappropriate medications than prescriptions on admission (P < 0.001). In contrast, there was no difference between prescriptions at discharge in terms of potential prescription omissions. Acute geriatric hospitalization in France improves prescriptions in terms of potentially inappropriate medication, but has no impact on potential prescription omissions. Further studies must be carried out to see if STOPP/START could be used as a tool in French prescription. © 2015 Japan Geriatrics Society.

Hierarchical screening for multiple mental disorders.

Science.gov (United States)

Batterham, Philip J; Calear, Alison L; Sunderland, Matthew; Carragher, Natacha; Christensen, Helen; Mackinnon, Andrew J

2013-10-01

There is a need for brief, accurate screening when assessing multiple mental disorders. Two-stage hierarchical screening, consisting of brief pre-screening followed by a battery of disorder-specific scales for those who meet diagnostic criteria, may increase the efficiency of screening without sacrificing precision. This study tested whether more efficient screening could be gained using two-stage hierarchical screening than by administering multiple separate tests. Two Australian adult samples (N=1990) with high rates of psychopathology were recruited using Facebook advertising to examine four methods of hierarchical screening for four mental disorders: major depressive disorder, generalised anxiety disorder, panic disorder and social phobia. Using K6 scores to determine whether full screening was required did not increase screening efficiency. However, pre-screening based on two decision tree approaches or item gating led to considerable reductions in the mean number of items presented per disorder screened, with estimated item reductions of up to 54%. The sensitivity of these hierarchical methods approached 100% relative to the full screening battery. Further testing of the hierarchical screening approach based on clinical criteria and in other samples is warranted. The results demonstrate that a two-phase hierarchical approach to screening multiple mental disorders leads to considerable increases efficiency gains without reducing accuracy. Screening programs should take advantage of prescreeners based on gating items or decision trees to reduce the burden on respondents. © 2013 Elsevier B.V. All rights reserved.

Safeguards for geological repositories

International Nuclear Information System (INIS)

Fattah, A.

2000-01-01

Direct disposal of spent nuclear fuel in geological repositories is a recognised option for closing nuclear fuel cycles. Geological repositories are at present in stages of development in a number of countries and are expected to be built and operated early next century. A State usually has an obligation to safely store any nuclear material, which is considered unsuitable to re-enter the nuclear fuel cycle, isolated from the biosphere. In conjunction with this, physical protection has to be accounted for to prevent inadvertent access to such material. In addition to these two criteria - which are fully under the State's jurisdiction - a third criterion reflecting international non-proliferation commitments needs to be addressed. Under comprehensive safeguards agreements a State concedes verification of nuclear material for safeguards purposes to the IAEA. The Agency can thus provide assurance to the international community that such nuclear material has been used for peaceful purposes only as declared by the State. It must be emphasised that all three criteria mentioned constitute a 'unit'. None can be sacrificed for the sake of the other, but compromises may have to be sought in order to make their combination as effective as possible. Based on comprehensive safeguards agreements signed and ratified by the State, safeguards can be terminated only when the material has been consumed or diluted in such a way that it can no longer be utilised for any nuclear activities or has become practicably irrecoverable. As such safeguards for nuclear material in geological repositories have to be continued even after the repository has been back-filled and sealed. The effective application of safeguards must assure continuity-of-knowledge that the nuclear material in the repository has not been diverted for an unknown purpose. The nuclear material disposed in a geological repository may eventually have a higher and long term proliferation risk because the inventory is

Revised draft: Southeastern Regional geologic characterization report. Volume 1

International Nuclear Information System (INIS)

1984-11-01

This report presents available geologic information pertinent to siting a repository for high-level nuclear waste in crystalline rock in Georgia, Maryland, North Carolina, South Carolina, and Virginia. For each of the states within the southeastern region, information is provided on the disqualifying factor and the screening variables to be used in region-to-area screening. These factors and variables include hydrologically significant natural resources, rock mass extent, postemplacement faulting, suspected Quaternary faulting, seismicity, rock and mineral resources, major ground-water discharge zones, water resources, ground-water salinity, and state of stress. Information is presented on the age, areal extent, shape, thickness of overburden, composition, texture, degree and type of alteration, and structural features associated with each rock body or complex. Regional seismic and tectonic information is presented, including patterns of earthquake occurrence, earthquake magnitudes, horizontal ground accelerations, and vertical crustal movements. Also included are discussions of the rock and mineral deposits or mines located within or near crystalline bodies; groundwater resources and regional hydrology; postulated changes in climate and the associated effects; and landforms, surface processes, and surficial materials on or near the subject rock bodies. A discussion of the relationship between the DOE Siting Guidelines and the geologic disqualifying factor and regional screening variables to be used in the region-to-area screening process is also presented

Fish screens at hydroelectric diversions

International Nuclear Information System (INIS)

Ott, R.F.

1994-01-01

Preventing downstream migrating fish from entering the turbines at hydroelectric projects is a standard mitigation goal of state and federal fishery management agencies. The object is to minimize the adverse impacts to the fish associated with the exclusion and passage through the bypass water conveyance facilities. In the western United States, most of the fishery management agencies have fish screen design criteria that focus on the approach and transportational velocities, maximum opening dimensions of the screen material, and the cleaning standards. Recently, more attention has been given to fish behavioral traits such as attraction and sustained and darting swimming speed, which has resulted in more attention to the position of the screens to the flow and the length of time the downstream migrants are exposed to the screens. Criteria for length of time of exposure, size and position of bypass, flow and velocities in the bypass entrances, discharge requirements back into the receiving water, and exposure to predation have created unique challenges to the fish screen designer. This paper discusses some of the more recent types of fixed fish screens that are being installed at hydroelectric plants that meet these challenges

Patient phenotypes in fibromyalgia comorbid with systemic sclerosis or rheumatoid arthritis: influence of diagnostic and screening tests. Screening with the FiRST questionnaire, diagnosis with the ACR 1990 and revised ACR 2010 criteria.

Science.gov (United States)

Perrot, Serge; Peixoto, Mariana; Dieudé, Philippe; Hachulla, Eric; Avouac, Jerome; Ottaviani, Sebastien; Allanore, Yannick

2017-01-01

Fibromyalgia (FM) may occur with rheumatoid arthritis (RA) and systemic sclerosis (SSc), and debate remains about its diagnosis. We aimed to use three FM tools (a screening tool (FiRST), diagnostic criteria (ACR 1990 and revised 2010), to compare FM prevalence between RA and SSc patients, to describe the phenotypes of patients with comorbid FM, and to analyze links between FM and secondary Sjögren's syndrome (SS). Consecutive adult patients with confirmed RA or SSc from four university hospitals were tested with the three FM tools. FiRST detected FM in 22.6% of the 172 RA patients, with confirmation in 22.1% (ACR1990) and 19.1% (ACR2010). ACR1990FM+ RA patients had more diffuse pain, whereas ACR2010FM+ RA patients had higher BMI and pain intensity, more diffuse pain, active disease, disability, and associated SS. FiRST detected FM in 27.8% of the 122 SSc patients, with confirmation in 30.3% (ACR1990) and 23.7% (ACR2010). ACR1990FM+ SSc patients had greater disability and pain intensity, and more diffuse pain, whereas ACR2010FM+ SSc patients had higher BMI, pain intensity, more disability and diffuse pain, and associated SS. Correlations between FM diagnostic and screening tool results were modest in both conditions. Secondary SS was associated with comorbid FM. The prevalence of FM is high in SSc and RA, whatever the FM diagnostic tool used. Secondary SS is associated with FM in both RA and SSc. The revised ACR 2010 FM criteria and FiRST screening tool reveal specific phenotypes potentially useful for improving disease management.

Criteria of reference radionuclides for safety analysis of spent fuel waste disposal

International Nuclear Information System (INIS)

Suryanto

1998-01-01

Study on the criteria for reference radionuclides selection for assessment on spent fuel disposal have done. The reference radionuclides in this study means radionuclides are predicted to contribute of the most radiological effect for man if spent fuel waste are discharged on deep geology formation. The research was done by investigate critically of parameters were used on evaluation a kind of radionuclide. Especially, this research study of parameter which relevant disposal case and or spent fuel waste on deep geology formation . The research assumed that spent fuel discharged on deep geology by depth 500-1000 meters from surface of the land. The migration scenario Radionuclides from waste form to man was assumed particularly for normal release in which Radionuclides discharge from waste form in a series thorough container, buffer, geological, rock, to fracture(fault) and move together with ground water go to biosphere and than go into human body. On this scenario, the parameter such as radionuclides inventory, half life, heat generation, hazard index based on maximum permissible concentration (MPC) or annual limit on intake (ALI) was developed as criteria of reference radionuclides selection. The research concluded that radionuclides inventory, half live, heat generated, hazard index base on MPC or ALI can be used as criteria for selection of reference Radionuclide. The research obtained that the main radionuclides are predicted give the most radiological effect to human are as Cs-137, Sr-90, I-129, Am-243, Cm-244, Pu-238, Pu-239, Pu-240. The radionuclides reasonable to be used as reference radionuclides in safety analysis at spent fuel disposal. (author)

Clinical evaluation of a new set of image quality criteria for mammography

International Nuclear Information System (INIS)

Grahn, A.; Hemdal, B.; Andersson, I.; Ruschin, M.; Thilander-Klang, A.; Boerjesson, S.; Tingberg, A.; Mattsson, S.; Haakansson, M.; Baath, M.; Maansson, L. G.; Medin, J.; Wanninger, F.; Panzer, W.

2005-01-01

The European Commission (EC) quality criteria for screen-film mammography are used as a tool to asses image quality. A new set of criteria was developed and initially tested in a previous study. In the present study, these criteria are further evaluated using screen-film mammograms that have been digitised, manipulated to simulated different image quality level and reprinted on film. Expert radiologists have evaluated these manipulated to simulate different image quality levels and reprinted on film. Expert radiologists have evaluated these manipulated images using both the original (EC) and the new criteria. A comparison of three different simulated dose levels that the new criteria yield a larger separation of image criteria scores than the old ones. These results indicated that the new set of image quality criteria has a higher discriminative power than the old set and thus seems to be more suitable for evaluation of image quality in mammography. (authors)

Systematic screening for unsafe driving due to medical conditions: Still debatable

Directory of Open Access Journals (Sweden)

Lagarde Emmanuel

2008-01-01

Full Text Available Abstract Background Assessing people's ability to drive has become a public health concern in most industrialized countries. Although age itself is not a predictive factor of an increased risk for dangerous driving, the prevalence of medical conditions that may impair driving increases with age. Because the implementation of a screening for unsafe driving due to medical conditions is a public health issue, its usefulness should be judged using standardised criteria already proposed for screening for chronic disease. The aim of this paper is to propose standardised criteria suitable to assess the scientific validity of screening for unsafe driving due to medical conditions, and identify potential issues to be clarified before screening can be implemented and effective. Discussion Using criteria developed for screening for chronic diseases and published studies on driving with medical conditions, we specify six criteria to judge the opportunity of screening for unsafe driving due to medical conditions. This adaptation was needed because of the complexity of the natural history of medical conditions and their potential consequences on driving and road safety. We then illustrate that published studies pleading for or against screening for unsafe driving due to medical conditions fail to provide the needed documentation. Individual criteria were mentioned in 3 to 72% of 36 papers pleading for or against screening. Quantitative estimates of relevant indicators were provided in at most 42% of papers, and some data, such as the definition of an appropriate unsafe driving period were never provided. Summary The standardised framework described in this paper provides a template for assessing the effectiveness (or lack of effectiveness of proposed measures for screening for unsafe driving due to medical conditions. Even if most criteria were mentioned in the published literature pleading for or against such a screening, the failure to find quantitative and

Acceptance-criteria for the bedrock for deep geologic disposal of spent nuclear fuel. Proceedings from a seminar at Gothenburg University; Acceptanskriterier foer berggrunden vid djup geologisk slutfoervaring av anvaent kaernbraensle

Energy Technology Data Exchange (ETDEWEB)

NONE

1995-11-01

The seminar was directed to Nordic participants, and discussed disposal in the Nordic crystalline bedrock. Criteria for the bedrock should include: It should give durable mechanical protection for the engineered barriers; give a stable and favorable chemical environment for these barriers; have a low turnover of ground water in the near field; be easy to characterize; give favorable recipient-conditions; not have valuable minerals in workable quantities. These general criteria raise several questions coupled to the safety analysis: e.g. the need for geological, hydrological and geochemical parameters. Which data are missing, which are most difficult to find? What should the site characterization program look like to focus on factors that are of the highest importance according to the safety analysis. The demands on the conditions at a site need to be translated into quantitative criteria, which should be expressed as values that can be measured at the site or deduced from such measurements. These questions were discussed at the seminar, and 21 contributions from Finnish, Norwegian and Swedish participants are reported in these proceedings under the chapters: Coupling to the safety analysis; Methodology and criteria for site selection in a regional geoscientific perspective; Rock as a building material - prognosis and result; Geoscientific criteria for the bedrock at the repository - Mechanical protection; Geoscientific criteria for the bedrock at the repository - Low ground water turnover, chemically favorable and stable environment in the near field; Geoscientific criteria for the bedrock at the repository - Demands on the bedrock concerning the migration of radionuclides.

Breast Cancer Screening

International Nuclear Information System (INIS)

Altaf, Fadwa J.

2004-01-01

Breast cancer is a very common health problem in Saudi females that can be reduced by early detection through introducing breast cancer screening. Literature review reveals significant reduction in breast cancer incidence and outcome after the beginning of breast cancer screening. The objectives of this article are to highlight the significance of breast cancer screening in different international societies and to write the major guidelines of breast cancer screening in relation to other departments involved with more emphasis on the Pathology Department guidelines in tissue handling, diagnostic criteria and significance of the diagnosis. This article summaries and acknowledges major work carried out before, and recommends similar modified work in order to meet the requirement for the Saudi society. (author)

Screening on urogenital Chlamydia trachomatis

Directory of Open Access Journals (Sweden)

Busse, Reinhard

2005-12-01

Full Text Available Introduction: Around 92 million urogenital infections are caused yearly by Chlamydia trachomatis worldwide [1]. The overall incidence of sexually transmitted diseases is increasing, as shown by the increases in the number of reported cases of syphilis and gonorrhea [2]. Chlamydia trachomatis infections are associated with various serious diseases in women, men and newborns, which could be, at least partially, avoided by means of early diagnosis and therapy. The Federal Joint Committee - responsible for decision-making concerning the benefit package of the German Social Health Insurance - has publicly announced the starting of deliberations on the issue of screening for Chlamydia trachomatis. Research Questions: The leading question to be answered is whether screening for Chlamydia trachomatis should be included in the German benefit basket. The aim of this report is to provide a summary of the available evidence concerning the issue of screening for Chlamydia trachomatis. Methods: The summary of published scientific evidence, including HTA reports, systematic reviews, guidelines and primary research is represented. The synthesis follows the structure given by the criteria of Wilson and Jungner [3] for the introduction of screening in a population: relevance of the condition, availability of an adequate test, effectiveness of screening, acceptance of the programme, and economical issues. A literature search was conducted for each aspect of the synthesis and the evidence has been summarised in evidence tables. Results: We identified five HTA reports from three European agencies [4], [5], [6], [7] and one from the USA [8]. In addition, we identified four guidelines from Northamerica [9], [10], [11], [12] and one from Europe [13]. A total of 56 primary research publications were included: relevance of the disease (n=26, availability of test (n=1, effectiveness of screening (n=11, acceptance of the programme (n=11, economical issues (n=7. Discussion

Geology and recognition criteria for uranium deposits of the quartz-pebble conglomerate type. Final report

Energy Technology Data Exchange (ETDEWEB)

Button, A.; Adams, S.S.

1981-03-01

This report is concerned with Precambrian uraniferous conglomerates. This class of deposit has been estimated to contain between approximately 16 and 35 percent of the global uranium reserve in two rather small areas, one in Canada, the other in South Africa. Similar conglomerates, which are often gold-bearing, are, however, rather widespread, being found in parts of most Precambrian shield areas. Data have been synthesized on the geologic habitat and character of this deposit type. The primary objective has been to provide the most relevant geologic observations in a structural fashion to allow resource studies and exploration to focus on the most prospective targets in the shortest possible time.

Geology and recognition criteria for uranium deposits of the quartz-pebble conglomerate type. Final report

International Nuclear Information System (INIS)

Button, A.; Adams, S.S.

1981-03-01

This report is concerned with Precambrian uraniferous conglomerates. This class of deposit has been estimated to contain between approximately 16 and 35 percent of the global uranium reserve in two rather small areas, one in Canada, the other in South Africa. Similar conglomerates, which are often gold-bearing, are, however, rather widespread, being found in parts of most Precambrian shield areas. Data have been synthesized on the geologic habitat and character of this deposit type. The primary objective has been to provide the most relevant geologic observations in a structural fashion to allow resource studies and exploration to focus on the most prospective targets in the shortest possible time

Revised draft: North Central Regional geologic characterization report. Volume 1

International Nuclear Information System (INIS)

1984-11-01

This report presents available geologic information pertinent to siting a repository for high-level nuclear waste in crystalline rock in Minnesota, Wisconsin, and the Upper Peninsula of Michigan. For each of the states within the North Central Region, information is provided on the disqualifying factor and the screening variables to be used in region-to-area screening. These factors and variables include hydrologically significant natural resources, rock mass extent, post-emplacement faulting, suspected Quaternary faulting, seismicity, rock and mineral resources, major groundwater discharge zones, water resources, groundwater salinity, and state of stress. Information is presented on age, areal extent, shape, thickness of overburden, composition, texture, degree and type of alteration, and structural features associated with each rock body or complex. Regional seismic and tectonic information is presented, including patterns of earthquake occurrence, earthquake magnitudes, horizontal ground accelerations, and vertical crustal movements. Also included are discussions of the rock and mineral deposits or mines located within or near crystalline rock bodies; groundwater resources and regional hydrology; postulated changes in climate and the associated effects; and landforms, surface processes, and surficial materials on or near the subject rock bodies. A discussion of the relationship between the DOE Siting Guidelines and the geologic disqualifying factor and regional screening variables to be used in the region-to-area screening process is also presented

Radiological protection criteria risk assessments for waste disposal options

International Nuclear Information System (INIS)

Hill, M.D.

1982-01-01

Radiological protection criteria for waste disposal options are currently being developed at the National Radiological Protection Board (NRPB), and, in parallel, methodologies to be used in assessing the radiological impact of these options are being evolved. The criteria and methodologies under development are intended to apply to all solid radioactive wastes, including the high-level waste arising from reprocessing of spent nuclear fuel (because this waste will be solidified prior to disposal) and gaseous or liquid wastes which have been converted to solid form. It is envisaged that the same criteria will be applied to all solid waste disposal options, including shallow land burial, emplacement on the ocean bed (sea dumping), geological disposal on land and sub-seabed disposal

Site suitability criteria for solidified high level waste repositories

International Nuclear Information System (INIS)

Heckman, R.A.; Holdsworth, T.; Towse, D.F.

1979-01-01

Activities devoted to development of regulations, criteria, and standards for storage of solidified high-level radioactive wastes are reported. The work is summarized in sections on site suitability regulations, risk calculations, geological models, aquifer models, human usage model, climatology model, and repository characteristics. Proposed additional analytical work is also summarized

One perspective on spatial variability in geologic mapping

Science.gov (United States)

Markewich, H.W.; Cooper, S.C.

1991-01-01

This paper discusses some of the differences between geologic mapping and soil mapping, and how the resultant maps are interpreted. The role of spatial variability in geologic mapping is addressed only indirectly because in geologic mapping there have been few attempts at quantification of spatial differences. This is largely because geologic maps deal with temporal as well as spatial variability and consider time, age, and origin, as well as composition and geometry. Both soil scientists and geologists use spatial variability to delineate mappable units; however, the classification systems from which these mappable units are defined differ greatly. Mappable soil units are derived from systematic, well-defined, highly structured sets of taxonomic criteria; whereas mappable geologic units are based on a more arbitrary heirarchy of categories that integrate many features without strict values or definitions. Soil taxonomy is a sorting tool used to reduce heterogeneity between soil units. Thus at the series level, soils in any one series are relatively homogeneous because their range of properties is small and well-defined. Soil maps show the distribution of soils on the land surface. Within a map area, soils, which are often less than 2 m thick, show a direct correlation to topography and to active surface processes as well as to parent material.

Behavior of rare earth elements in fractured aquifers: an application to geological disposal criteria for radioactive waste

International Nuclear Information System (INIS)

Lee, Seung Gu; Kim, Yong Je; Lee, Kil Yong; Kim, Kun Han

2003-01-01

An understanding of the geochemistry of potential host rocks is very important in the site evaluation for construction of an underground geologic repository for radioactive waste. Because of similar valence and ionic radii and high similarity in electronic structure with trivalent actinides (such as Am 3+ and Cm 3+ ), the rare earth elements (REEs) have been used to predict the behavior of actinide-series elements in solution (Runde et al., 1992). For Am and Cm, which occur only in the trivalent states in most waste-disposal repository environments, the analogy with the REEs is particularly relevant. In order to discuss the behavior of REEs in geological media and to deduce the behavior of actinides in geological environments based on the REE abundance, and to provide an useful tool in deciding an optimum geological condition for radioactive disposal, we estimated the REE abundance from various kinds of fractured rock type. In fractured granitic aquifer, chondrite-normalized REE pattern show Eu positive anomaly due to fracture-filling calcite precipitation. However, in fractured meta-basaltic and volcanic tuffaceous aquifer, REE pattern do not show the change of Eu anomaly due to fracture-filling calcite precipitation. Eu shows very similar properties such as cohesive energy, ionic radii with coordination number compared to Am. Therefore, if we consider the Eu behavior in fractured rocks and the similar physical/chemical properties of Eu and Am, together, our results strongly suggest that Eu is a very useful analogue for predicting the behavior of Am in geological environment

Screening for type 2 diabetes: a short report for the National Screening Committee.

Science.gov (United States)

Waugh, N R; Shyangdan, D; Taylor-Phillips, S; Suri, G; Hall, B

2013-08-01

The prevalence of type 2 diabetes mellitus (T2DM) has been increasing, owing to increases in overweight and obesity, decreasing physical activity and the changing demographic structure of the population. People can develop T2DM without symptoms and up to 20% may be undiagnosed. They may have diabetic complications, such as retinopathy, by the time they are diagnosed, or may suffer a heart attack, without warning. Undiagnosed diabetes can be detected by raised blood glucose levels. The aim of this review was to provide an update for the UK National Screening Committee (NSC) on screening for T2DM. As this review was undertaken to update a previous Health Technology Assessment review published in 2007, and a more recent Scottish Public Health Network review, searches for evidence were restricted from 2009 to end of January 2012, with selected later studies added. The databases searched were MEDLINE, EMBASE, MEDLINE-in-Process & Other Non-Indexed Citations, Science Citation Index and Conference Proceedings Citation Index. The case for screening was considered against the criteria used by the NSC to assess proposed population screening programmes. Population screening for T2DM does not meet all of the NSC criteria. Criterion 12, on optimisation of existing management, has not been met. A report by the National Audit Office (NAO) gives details of shortcomings. Criterion 13 requires evidence from high-quality randomised controlled trials that screening is beneficial. This has not been met. The Ely trial of screening showed no benefit. The ADDITION trial was not a trial of screening, but showed no benefit in cardiovascular outcomes from intensive management in people with screen-detected T2DM. Criterion 18 on staffing and facilities does not appear to have been met, according to the NAO report. Criterion 19 requires that all other options, including prevention, should have been considered. A large proportion of cases of T2DM could be prevented if people avoided becoming

Aesthetics-based classification of geological structures in outcrops for geotourism purposes: a tentative proposal

Science.gov (United States)

Mikhailenko, Anna V.; Nazarenko, Olesya V.; Ruban, Dmitry A.; Zayats, Pavel P.

2017-03-01

The current growth in geotourism requires an urgent development of classifications of geological features on the basis of criteria that are relevant to tourist perceptions. It appears that structure-related patterns are especially attractive for geotourists. Consideration of the main criteria by which tourists judge beauty and observations made in the geodiversity hotspot of the Western Caucasus allow us to propose a tentative aesthetics-based classification of geological structures in outcrops, with two classes and four subclasses. It is possible to distinguish between regular and quasi-regular patterns (i.e., striped and lined and contorted patterns) and irregular and complex patterns (paysage and sculptured patterns). Typical examples of each case are found both in the study area and on a global scale. The application of the proposed classification permits to emphasise features of interest to a broad range of tourists. Aesthetics-based (i.e., non-geological) classifications are necessary to take into account visions and attitudes of visitors.

Region-to-area screening methodology for the Crystalline Repository Project

International Nuclear Information System (INIS)

1985-04-01

The purpose of this document is to describe the Crystalline Repository Project's (CRP) process for region-to-area screening of exposed and near-surface crystalline rock bodies in the three regions of the conterminous United States where crystalline rock is being evaluated as a potential host for the second nuclear waste repository (i.e., in the North Central, Northeastern, and Southeastern Regions). This document indicates how the US Department of Energy's (DOE) General Guidelines for the Recommendation of Sites for Nuclear Waste Repositories (10 CFR 960) were used to select and apply factors and variables for the region-to-area screening, explains how these factors and variable are to be applied in the region-to-area screening, and indicates how this methodology relates to the decision process leading to the selection of candidate areas. A brief general discussion of the screening process from the national survey through area screening and site recommendation is presented. This discussion sets the scene for detailed discussions which follow concerning the region-to-area screening process, the guidance provided by the DOE Siting Guidelines for establishing disqualifying factors and variables for screening, and application of the disqualifying factors and variables in the screening process. This document is complementary to the regional geologic and environmental characterization reports to be issued in the summer of 1985 as final documents. These reports will contain the geologic and environmental data base that will be used in conjunction with the methodology to conduct region-to-area screening

Risk assessment of soil contamination criteria

International Nuclear Information System (INIS)

King, C.M.; Marter, W.L.; Montaque, D.F.; Holton, G.A.

1987-06-01

Criteria have been developed to select radioactive and nonradioactive contaminants at waste sites detailed analysis and risk assessment. These criteria were based on soil and water quality guidelines developed by various government agencies to determine if the criteria were appropriate. We performed a risk assessment of a hypothetical site which contained radioactive and nonradioactive contaminants at levels equal to the criteria values. Risks to the public from atmospheric, surface water, and groundwater exposure pathways were examined. Health risks to the public from atmospheric releases of radioactive and nonradioactive materials from a waste at soil criteria contamination levels are low. Health risks to the maximally exposed individual to chemical carcinogens are considerably below traditional EPA action levels. And health risks to the maximally exposed individual to atmospherically released radioactive contaminants is 1.88 x 10 -7 , more than a factor of 5 less than 10 -6 . Based on our atmospheric exposure pathways analysis and risk assessment, the applied soil criteria are appropriate for screening out unimportant risk contributors to human health from atmospheric exposure pathways. 13 refs., 3 figs., 7 tabs

Statewide screening for low-level radioactive waste shallow land burial sites

International Nuclear Information System (INIS)

Staub, W.P.; Cannon, J.B.; Stratton, L.E.

1984-01-01

A methodology was developed for statewide low-level waste site screening based on NRC site selection criteria. The methodology and criteria were tested in Tennessee to determine their effectiveness in narrowing the choice of sites for more intensive localized site screening. The statewide screening methodology entailed two steps. The first step was to select one or more physiographic provinces wherein sites meeting the criteria were most likely to be found. The second step was to select one or more suitable outcrop bands from within the most favorable physiographic provinces. These selections were based entirely on examination of existing literature and maps at scales no larger than 1:250,000. The statewide screening project identified only one suitable physiographic province (the Mississippi Embayment region) and one favorable outcrop band (the Coon Creek Formation) within a three county area of western Tennessee. Ground water monitoring and predictability proved to be the most difficult criterion to meet. This criterion alone eliminated other outcrop bands in the Mississippi Embayment as well as the Eastern Highland Rim and Western Highland Rim physiographic provinces. Other provinces failed to meet several screening criteria. 3 references, 3 figures, 1 table

Scientific Evidence for Different Options for GDM Screening and Management: Controversies and Review of the Literature

Directory of Open Access Journals (Sweden)

Claudia Caissutti

2017-01-01

Full Text Available Background. Gestational diabetes (GDM affects up to 7% of pregnant women and is associated with several maternal and perinatal morbidities. International organizations suggest several different recommendations regarding how to screen and to manage GDM. Objective. We aimed to analyze the most important and employed guidelines about screening and management of GDM and we investigated existing related literature. Results. We found several different criteria for screening for GDM, for monitoring GDM, and for starting pharmacological therapy. When using IADPSG criteria, GDM rate increased, perinatal outcomes improved, and screening became cost-effective. Compared to no treatment, treatment of women meeting criteria for GDM by IADPSG criteria but not by other less strict criteria has limited evidence for an effect on adverse pregnancy outcomes.

Submarine geologic disposal of nuclear waste

International Nuclear Information System (INIS)

Hollister, C.D.; Corliss, B.H.; Anderson, D.R.

1980-01-01

Site suitability characteristics of submarine geological formations for the disposal of radioactive wastes include the distribution coefficient of the host medium, permeability, viscoelastic nature of the sediments, influence of organic material on remobilization, and effects of thermal stress. The submarine geological formation that appears to best satisfy these criteria is abyssal ''red'' clay. Regions in the ocean that have coarse-grained deposits, high or variable thermal conductivity, high organic carbon content, and sediment thickness of less than 50 m are not being considered at this time. The optimum geological environment should be tranquil and have environmental predictability over a minimum of 10 5 years. Site selection activities for the North Atlantic and North Pacific are reviewed and future activities which include international cooperation are discussed. A paleoenvironmental model for Cenozoic sedimentation in the central North Pacific is presented based on studies of a long core from the Mid-Plate Gyre MPG-1 area, and is an example of the type of study that will be carried out in other seabed study areas. The data show that the MPG-1 region has been an area of slow, continuous accumulation during the past 65 million years. (author)

Developing criteria to establish Trusted Digital Repositories

Science.gov (United States)

Faundeen, John L.

2017-01-01

This paper details the drivers, methods, and outcomes of the U.S. Geological Survey’s quest to establish criteria by which to judge its own digital preservation resources as Trusted Digital Repositories. Drivers included recent U.S. legislation focused on data and asset management conducted by federal agencies spending $100M USD or more annually on research activities. The methods entailed seeking existing evaluation criteria from national and international organizations such as International Standards Organization (ISO), U.S. Library of Congress, and Data Seal of Approval upon which to model USGS repository evaluations. Certification, complexity, cost, and usability of existing evaluation models were key considerations. The selected evaluation method was derived to allow the repository evaluation process to be transparent, understandable, and defensible; factors that are critical for judging competing, internal units. Implementing the chosen evaluation criteria involved establishing a cross-agency, multi-disciplinary team that interfaced across the organization. 

CQUESTRA, a risk and performance assessment code for geological sequestration of carbon dioxide

International Nuclear Information System (INIS)

LeNeveu, D.M.

2008-01-01

A computationally efficient semi-analytical code, CQUESTRA, has been developed for probabilistic risk assessment and rapid screening of potential sites for geological sequestration of carbon dioxide. The rate of dissolution and leakage from a trapped underground pool of carbon dioxide is determined. The trapped carbon dioxide could be mixed with hydrocarbons and other components to form a buoyant phase. The program considers potential mechanisms for escape from the geological formations such as the movement of the buoyant phase through failed seals in wellbores, the annulus around wellbores and through open fractures in the caprock. Plume animations of dissolved carbon dioxide in formation water around the wellbores are provided. Solubility, density and viscosity of the buoyant phase are determined by equations of state. Advection, dispersion, diffusion, buoyancy, aquifer flow rates and local formation fluid pressure are taken into account in the modeling of the carbon dioxide movement. Results from a hypothetical example simulation based on data from the Williston basin near Weyburn, Saskatchewan, indicate that this site is potentially a viable candidate for carbon dioxide sequestration. Sensitivity analysis of CQUESTRA indicates that criteria such as siting below aquifers with large flow rates and siting in reservoirs having fluid pressure below the pressure of the formations above can promote complete dissolution of the carbon dioxide during movement toward the surface, thereby preventing release to the biosphere. Formation of very small carbon dioxide bubbles within the fluid in the wellbores can also lead to complete dissolution

Geological evaluation of Gulf Coast salt domes: overall assessment of the Gulf Interior Region

International Nuclear Information System (INIS)

1981-10-01

The three major phases in site characterization and selection are regional studies, area studies, and location studies. This report characterizes regional geologic aspects of the Gulf Coast salt dome basins. It includes general information from published sources on the regional geology; the tectonic, domal, and hydrologic stability; and a brief description the salt domes to be investigated. After a screening exercise, eight domes were chosen for further characterization: Keechi, Oakwood, and Palestine Domes in Texas; Vacherie and Rayburn's domes in North Louisiana; and Cypress Creek and Richton domes in Mississippi. A general description of each, maps of the location, property ownership, and surface geology, and a geologic cross section were presented for each dome

Geological evaluation of Gulf Coast salt domes: overall assessment of the Gulf Interior Region

Energy Technology Data Exchange (ETDEWEB)

None

1981-10-01

The three major phases in site characterization and selection are regional studies, area studies, and location studies. This report characterizes regional geologic aspects of the Gulf Coast salt dome basins. It includes general information from published sources on the regional geology; the tectonic, domal, and hydrologic stability; and a brief description the salt domes to be investigated. After a screening exercise, eight domes were chosen for further characterization: Keechi, Oakwood, and Palestine Domes in Texas; Vacherie and Rayburn's domes in North Louisiana; and Cypress Creek and Richton domes in Mississippi. A general description of each, maps of the location, property ownership, and surface geology, and a geologic cross section were presented for each dome.

Spent fuel performance in geologic repository environments

International Nuclear Information System (INIS)

Bradley, D.J.

1985-10-01

The performance assessment of the waste package is a current area of study in the United States program to develop a geologic repository for nuclear waste isolation. The waste package is presently envisioned as the waste form and its surrounding containers and possibly a packing material composed of crushed host rock or mixtures of that rock with clays. This waste package is tied to performance criteria set forth in recent legislation. It is the goal of the Civilian Radioactive Waste Management Program to obtain the necessary information on the waste package, in several geologic environments, to show that the waste package provides reasonable assurance of meeting established performance criteria. This paper discusses the United States program directed toward managing high-level radioactive waste, with emphasis on the current effort to define the behavior of irradiated spent fuel in repository groundwaters. Current studies are directed toward understanding the rate and nature (such as valence state, colloid form if any, solid phase controlling solubility) of radionuclide release from the spent fuel. Due to the strong interactive effect of radiation, thermal fields, and waste package components on this release, current spent fuel studies are being conducted primarily in the presence of waste package components over a wide range of potential environments

Geological-structural interpretation using products of remote sensing in the region of Carrancas, Minas Gerais, Brazil

Science.gov (United States)

Parada, N. D. J. (Principal Investigator); Dossantos, A. R.; Dosanjos, C. E.; Barbosa, M. P.; Veneziani, P.

1982-01-01

The efficiency of some criteria developed for the utilization of small scale and low resolution remote sensing products to map geological and structural features was demonstrated. Those criteria were adapted from the Logical Method of Photointerpretation which consists of textural qualitative analysis of landforms and drainage net patterns. LANDSAT images of channel 5 and 7, 4 LANDSAT-RBV scenes, and 1 radar mosiac were utilized. The region of study is characterized by supracrustal metassediments (quartzites and micaschist) folded according to a "zig-zag" pattern and gnaissic basement. Lithological-structural definition was considered outstanding when compared to data acquired during field work, bibliographic data and geologic maps acquired in larger scales.

Medicatiescreening met Beers-criteria en STOPP/START-criteria bij de ouedere patient: associatie tussen potentieel ongewenst geneesmiddelengebruik en geneesmiddelgerelateerde ziekenhuisopnamen

NARCIS (Netherlands)

Stelt, CAK; Vermeulen Windsant - van der Tweel, AMA; Egberts, ACG; Van Den Bemt, Patricia M L A; Leendertse, AJ; Hermens, W.Th.; van Marum, R.J.; Derijks, H.J.

2015-01-01

Medication screening using Beers and stopp/start criteria for elderly patients: association between potentially inappropriate medication and medication-related hospital admissions OBJECTIVE To assess the risk of medication-related hospital admissions associated with inappropriate medication use

Vascular injury outcomes with screening implementation

Directory of Open Access Journals (Sweden)

James D. Weinberg, MD

2017-09-01

Full Text Available Blunt carotid and vertebral artery injuries (BCVI are generally viewed as rare events. Screening guidelines based on the Memphis and Denver data were put into place at Palmetto Health Richland in August of 2008. This study aims to look at the incidence of BCVI 2 years before the guidelines were put into place and then 2 years after. A total of 11,005 trauma patients presented during our study period. 98 patients were determined to have BCVI and met inclusion criteria: 21 in the Control group and 77 in the Screening group. A total of 16 deaths and 14 strokes were recorded in the study population. The odds of patients in the Screening group dying were 29% lower than that of a patient in the Control group [OR: 0.71, (95% CI: 0.20–2.50; p = 0.59], after adjusting for ISS. The odds of developing a stroke in the Screening group were 69% lower than the Control group [OR: 0.31 (0.09–1.08; p = 0.067]. These differences were not statistically significant. The increased BCVI incidence rate and decreased stroke and mortality rate following screening implementation further support the importance of having screening criteria for blunt vascular injury following trauma.

STOPP/START criteria for potentially inappropriate prescribing in older people: version 2.

Science.gov (United States)

O'Mahony, Denis; O'Sullivan, David; Byrne, Stephen; O'Connor, Marie Noelle; Ryan, Cristin; Gallagher, Paul

2015-03-01

Screening tool of older people's prescriptions (STOPP) and screening tool to alert to right treatment (START) criteria were first published in 2008. Due to an expanding therapeutics evidence base, updating of the criteria was required. We reviewed the 2008 STOPP/START criteria to add new evidence-based criteria and remove any obsolete criteria. A thorough literature review was performed to reassess the evidence base of the 2008 criteria and the proposed new criteria. Nineteen experts from 13 European countries reviewed a new draft of STOPP & START criteria including proposed new criteria. These experts were also asked to propose additional criteria they considered important to include in the revised STOPP & START criteria and to highlight any criteria from the 2008 list they considered less important or lacking an evidence base. The revised list of criteria was then validated using the Delphi consensus methodology. The expert panel agreed a final list of 114 criteria after two Delphi validation rounds, i.e. 80 STOPP criteria and 34 START criteria. This represents an overall 31% increase in STOPP/START criteria compared with version 1. Several new STOPP categories were created in version 2, namely antiplatelet/anticoagulant drugs, drugs affecting, or affected by, renal function and drugs that increase anticholinergic burden; new START categories include urogenital system drugs, analgesics and vaccines. STOPP/START version 2 criteria have been expanded and updated for the purpose of minimizing inappropriate prescribing in older people. These criteria are based on an up-to-date literature review and consensus validation among a European panel of experts. © The Author 2014. Published by Oxford University Press on behalf of the British Geriatrics Society.

Informed choice about Down syndrome screening

DEFF Research Database (Denmark)

Skjøth, Mette Maria; Draborg, Eva; Lamont, Ronald Francis

2015-01-01

INTRODUCTION: The aim of this study was to evaluate the effect of an eHealth intervention (interactive website) on pregnant women's ability to make an informed choice about Down syndrome screening. MATERIAL AND METHODS: The study was designed as a randomized controlled trial with allocation...... to an intervention group and a control group in a ratio of 1:1. Subsequent subgroup analysis was conducted. Participants were recruited from 5 August 2013 to 25 April 2014 at Odense University Hospital, Denmark. Inclusion criteria were: pregnant women aged ≥18 years who were invited to participate in Down syndrome...... screening. Exclusion criteria were: high risk of abortion, psycho-socially vulnerable women, late referral, inability to speak Danish and women declining to participate. The primary outcome was informed choice about Down syndrome screening. The Multidimensional Measure of Informed Choice was used to assess...

Prevention of Hospital-Acquired Adverse Drug Reactions in Older People Using Screening Tool of Older Persons' Prescriptions and Screening Tool to Alert to Right Treatment Criteria: A Cluster Randomized Controlled Trial.

Science.gov (United States)

O'Connor, Marie N; O'Sullivan, David; Gallagher, Paul F; Eustace, Joseph; Byrne, Stephen; O'Mahony, Denis

2016-08-01

To determine whether use of the Screening Tool of Older Persons' Prescriptions (STOPP) and Screening Tool to Alert to Right Treatment (START) criteria reduces incident hospital-acquired adverse drug reactions (ADRs), 28-day medication costs, and median length of hospital stay in older adults admitted with acute illness. Single-blind cluster randomized controlled trial (RCT) of unselected older adults hospitalized over a 13-month period. Tertiary referral hospital in southern Ireland. Consecutively admitted individuals aged 65 and older (N = 732). Single time point presentation to attending physicians of potentially inappropriate medications according to the STOPP/START criteria. The primary outcome was the proportion of participants experiencing one or more ADRs during the index hospitalization. Secondary outcomes were median length of stay (LOS) and 28-day total medication cost. One or more ADRs occurred in 78 of the 372 control participants (21.0%; median age 78, interquartile range (IQR) 72-84) and in 42 of the 360 intervention participants (11.7%; median age 80, IQR 73-85) (absolute risk reduction = 9.3%, number needed to treat = 11). The median LOS in the hospital was 8 days (IQR 4-14 days) in both groups. At discharge, median medication cost was significantly lower in the intervention group (€73.16, IQR €38.68-121.72) than in the control group (€90.62, IQR €49.38-162.53) (Wilcoxon rank test Z statistic = -3.274, P older adults but did not affect median LOS. © 2016, Copyright the Authors Journal compilation © 2016, The American Geriatrics Society.

Engineering Geology | Alaska Division of Geological & Geophysical Surveys

Science.gov (United States)

Alaska's Mineral Industry Reports AKGeology.info Rare Earth Elements WebGeochem Engineering Geology Alaska content Engineering Geology Additional information Engineering Geology Posters and Presentations Alaska Alaska MAPTEACH Tsunami Inundation Mapping Engineering Geology Staff Projects The Engineering Geology

Osmotic generation of 'anomalous' fluid pressures in geological environments

Science.gov (United States)

Neuzii, C.E.

2000-01-01

Osmotic pressures are generated by differences in chemical potential of a solution across a membrane. But whether osmosis can have a significant effect on the pressure of fluids in geological environments has been controversial, because the membrane properties of geological media are poorly understood. 'Anomalous' pressures - large departures from hydrostatic pressure that are not explicable in terms of topographic or fluid-density effects are widely found in geological settings, and are commonly considered to result from processes that alter the pore or fluid volume, which in turn implies crustal changes happening at a rate too slow to observe directly. Yet if osmosis can explain some anomalies, there is no need to invoke such dynamic geological processes in those cases. Here I report results of a nine- year in situ measurement of fluid pressures and solute concentrations in shale that are consistent with the generation of large (up to 20 MPa) osmotic-pressure anomalies which could persist for tens of millions of years. Osmotic pressures of this magnitude and duration can explain many of the pressure anomalies observed in geological settings. The require, however, small shale porosity and large contrasts in the amount of dissolved solids in the pore waters - criteria that may help to distinguish between osmotic and crystal-dynamic origins of anomalous pressures.

Technical assessment concept of geological aspect to define site NPP prospectus in Indonesia

International Nuclear Information System (INIS)

Akhmad Muktaf Haifani

2013-01-01

Geological aspects become an important aspect in determining the prospective nuclear power plant site. Geological investigation can be categorized based on the spatial scale of Regional and Local and every stage will have different levels of investigation. Understanding Regional Tectonics and Regional Geology of Indonesia is very important and helps to facilitate the evaluators to review documents. Unification of standard of site conformity assessment in terms tectonic aspect particularly geological stability becomes very necessary in the assessment of the suitability of the proposed licensed document, given the tectonic-forming process in Indonesia is highly variable. Safety criteria is key parameters that must be considered to solve any problems and a proper bridge in determining the site parameters of the proposed by applicants and compliance with any requirement of Regulatory Body. (author)

Review of the scientific and technical criteria for the Waste Isolation Pilot Plant (WIPP)

International Nuclear Information System (INIS)

1984-01-01

The panel has evaluated the scientific and technical adequacy of work being done on the Waste Isolation Pilot Plant (WIPP) project to satisfy the charge to the panel set out in Chapter 1. The panel concluded that the scientific work has been carried out with a high degree of professional competence. The panel notes that the geology revealed by shaft sinking and excavation of drifts and the preliminary measurements generally confirm the geologic expectations derived from surface explorations and boreholes. The purity and volume of the salt, the absence of brine pockets at the repository horizon in the areas excavated, the absence of breccia pipes and of toxic gases, and the nearly horizontal bedding of the salt indicate that a repository can be constructed that will meet the geologic criteria for site selection. Thus, the important issues about the geology at the site have been resolved, but there remain some issues about the hydrology and design of the facility that should be resolved before large-scale transuranic (TRU) waste emplacement begins. The panel's conclusions and recommendations regarding the following studies are presented: site selection and characterization; in-situ tests and experiments; waste acceptance criteria; design and construction of underground facilities; and performance assessment. 65 references, 17 figures, 3 tables

A proposal for the use of uniform diagnostic criteria for gestational diabetes in Europe

DEFF Research Database (Denmark)

Benhalima, Katrien; Mathieu, Chantal; Damm, Peter

2015-01-01

Screening and diagnostic criteria for gestational diabetes (GDM) are inconsistent across Europe, and the development of a uniform GDM screening strategy is necessary. Such a strategy would create opportunities for more women to receive timely treatment for GDM. Developing a consensus on screening......-off values for diabetes outside pregnancy, with particular efforts made to screen high-risk groups. When screening for GDM is performed at 24 weeks' gestation or later, the proposal is now to use the 75 g OGTT with the new WHO diagnostic criteria for GDM. However, more research is necessary to evaluate...... for GDM in Europe is challenging, as populations are diverse and healthcare delivery systems also differ. The European Board & College of Obstetrics and Gynaecology (EBCOG) has responded to this challenge by appointing a steering committee, including members of the EBCOG and the Diabetic Pregnancy Study...

Prevalence of Metabolic Syndrome and Individual Criteria in College Students

Science.gov (United States)

Fernandes, Jill; Lofgren, Ingrid E.

2011-01-01

Metabolic syndrome (MetS) is present in young adults and because coronary heart disease (CHD) is likely, screening to determine MetS prevalence and its criteria is critical. Objective: To determine MetS prevalence and most prevalent criteria in a sample of first-year college students. Participants: First-year college students between 18 and 24…

Radioactive waste disposal in geological formations

International Nuclear Information System (INIS)

Gera, F.

1977-01-01

The nuclear energy controversy, now raging in several countries, is based on two main issues: the safety of nuclear plants and the possibility to dispose safely of the long-lived radioactive wastes. Consideration of the evolution of the hazard potential of waste in function of decay time leads to a somewhat conservative reference containment time in the order of one hundred thousand years. Several concepts have been proposed for the disposal of long-lived wastes. At the present time, emplacement into suitable geological formations under land areas can be considered the most promising disposal option. It is practically impossible to define detailed criteria to be followed in selecting suitable sites for disposal of long-lived wastes. Basically there is a single criterion, namely; that the geological environment must be able to contain the wastes for at least a hundred thousand years. However, due to the extreme variability of geological settings, it is conceivable that this basic capability could be provided by a great variety of different conditions. The predominant natural mechanism by which waste radionuclides could be moved from a sealed repository in a deep geological formation into the biosphere is leaching and transfer by ground water. Hence the greatest challenge is to give a satisfactory demonstration that isolation from ground water will persist over the required containment time. Since geological predictions are necessarily affected by fairly high levels of uncertainty, the only practical approach is not a straight-forward forecast of future geological events, but a careful assessment of the upper limits of geologic changes that could take place in the repository area over the next hundred thousand years. If waste containment were to survive these extreme geological changes the disposal site could be considered acceptable. If some release of activity were to take place in consequence of the hypothetical events the disposal solution might still be

Volcanogenic Uranium Deposits: Geology, Geochemical Processes, and Criteria for Resource Assessment

Science.gov (United States)

Nash, J. Thomas

2010-01-01

Felsic volcanic rocks have long been considered a primary source of uranium for many kinds of uranium deposits, but volcanogenic uranium deposits themselves have generally not been important resources. Until the past few years, resource summaries for the United States or the world generally include volcanogenic in the broad category of 'other deposits' because they comprised less than 0.5 percent of past production or estimated resources. Exploration in the United States from the 1940s through 1982 discovered hundreds of prospects in volcanic rocks, of which fewer than 20 had some recorded production. Intensive exploration in the late 1970s found some large deposits, but low grades (less than about 0.10 percent U3O8) discouraged economic development. A few deposits in the world, drilled in the 1980s and 1990s, are now known to contain large resources (>20,000 tonnes U3O8). However, research on ore-forming processes and exploration for volcanogenic deposits has lagged behind other kinds of uranium deposits and has not utilized advances in understanding of geology, geochemistry, and paleohydrology of ore deposits in general and epithermal deposits in particular. This review outlines new ways to explore and assess for volcanogenic deposits, using new concepts of convection, fluid mixing, and high heat flow to mobilize uranium from volcanic source rocks and form deposits that are postulated to be large. Much can also be learned from studies of epithermal metal deposits, such as the important roles of extensional tectonics, bimodal volcanism, and fracture-flow systems related to resurgent calderas. Regional resource assessment is helped by genetic concepts, but hampered by limited information on frontier areas and undiscovered districts. Diagnostic data used to define ore deposit genesis, such as stable isotopic data, are rarely available for frontier areas. A volcanic environment classification, with three classes (proximal, distal, and pre-volcanic structures

Location performance objectives for the NNWSI area-to-location screening activity

Energy Technology Data Exchange (ETDEWEB)

Sinnock, S.; Fernandez, J.A.

1984-01-01

Fifty-four objectives were identified to guide the screening of the Nevada Research and Development Area of the Nevada Test Site for relatively favorable locations for the disposal of nuclear waste in a mined geologic repository. The objectives were organized as a hierarchy composed of 4 upper-level, 12 middle-level, and 38 lower-level objectives. The four upper-level objectives account for broad national goals to contain and isolate nuclear waste in an environmentally sound and economically acceptable manner. The middle-level objectives correspond to topical categories that logically relate the upper-level objectives to site-specific concerns such as seismicity, sensitive species, and flooding hazards (represented by the lower-level objectives). The relative merits of alternative locations were compared by an application of decision analysis based on standard utility theory. The relative favorabilities of pertinent physical conditions at each alternative location were weighted in relation to the importance of objectives, and summed to produce maps indicating the most and the least favorable locations. Descriptions of the objectives were organized by the hierarchical format; they detail the applicability of each objective to geologic repository siting, previously published siting criteria corresponding to each objective, and the rationale for the weight assigned to each objective, and the pertinent attributes for evaluating locations with respect to each objective. 51 references, 47 figures, 4 tables.

Location performance objectives for the NNWSI area-to-location screening activity

International Nuclear Information System (INIS)

Sinnock, S.; Fernandez, J.A.

1984-01-01

Fifty-four objectives were identified to guide the screening of the Nevada Research and Development Area of the Nevada Test Site for relatively favorable locations for the disposal of nuclear waste in a mined geologic repository. The objectives were organized as a hierarchy composed of 4 upper-level, 12 middle-level, and 38 lower-level objectives. The four upper-level objectives account for broad national goals to contain and isolate nuclear waste in an environmentally sound and economically acceptable manner. The middle-level objectives correspond to topical categories that logically relate the upper-level objectives to site-specific concerns such as seismicity, sensitive species, and flooding hazards (represented by the lower-level objectives). The relative merits of alternative locations were compared by an application of decision analysis based on standard utility theory. The relative favorabilities of pertinent physical conditions at each alternative location were weighted in relation to the importance of objectives, and summed to produce maps indicating the most and the least favorable locations. Descriptions of the objectives were organized by the hierarchical format; they detail the applicability of each objective to geologic repository siting, previously published siting criteria corresponding to each objective, and the rationale for the weight assigned to each objective, and the pertinent attributes for evaluating locations with respect to each objective. 51 references, 47 figures, 4 tables

A state geological survey commitment to environmental geology - the Texas Bureau of Economic Geology

International Nuclear Information System (INIS)

Wermund, E.G.

1990-01-01

In several Texas environmental laws, the Bureau of Economic Geology is designated as a planning participant and review agency in the process of fulfilling environmental laws. Two examples are legislation on reclamation of surface mines and regulation of processing low level radioactive wastes. Also, the Bureau is the principal geological reviewer of all Environmental Assessments and Environmental Impact Statements which the Office of the Governor circulates for state review on all major developmental activities in Texas. The BEG continues its strong interest in environmental geology. In February 1988, it recommitted its Land Resources Laboratory, initiated in 1974, toward fulfilling needs of state, county, and city governments for consultation and research on environmental geologic problems. An editorial from another state geological survey would resemble the about description of texas work in environmental geology. State geological surveys have led federal agencies into many developments of environmental geology, complemented federal efforts in their evolution, and continued a strong commitment to the maintenance of a quality environment through innovative geologic studies

Diagnostic criteria for gestational diabetes mellitus (WS 331-2011)

Institute of Scientific and Technical Information of China (English)

Medical Service Specialty Standard Committee of Mi

2012-01-01

The criteria provide the screening and diagnosis for gestational diabetes mellitus and it should be applied to all medical institutions and health care practitioners for gestational diabetes mellitus (DM) diagnosis in China.

RADIATION ACCESS ZONE AND VENTILATION CONFINEMENT ZONE CRITERIA FOR THE MGR SURFACE FACILITIES

International Nuclear Information System (INIS)

D. A. Padula

2000-01-01

The objectives of this technical report are to: (1) Establish the criteria for Radiation Access Zone (RAZ) designation. (2) Establish the criteria for the Ventilation Confinement Zone (VCZ) designation. The scope will be to formulate the RAZ and VCZ zoning designation for the Monitored Geologic Repository (MGR) surface facilities and to apply the zoning designations to the current Waste Handling Building (WHB), Waste Treatment Building (WTB), and Carrier Preparation Building (CPB) configurations

Referral criteria for school-based hearing screening in South Africa ...

African Journals Online (AJOL)

Faheema Mahomed-Asmail

Available online xxx. Keywords: ... ciently low for a cost-effective and sustainable programme. The study aim was to .... cost-effectiveness and feasibility of hearing screening ..... Lopez, A. D., Mathers, C. D., Ezzati, M., Jamison, D. T., & · Murray ...

Comprehensive Evaluation Criteria for English Learning Websites Using Expert Validity Surveys

Science.gov (United States)

Yang, Ya-Ting C.; Chan, Chia-Ying

2008-01-01

This study aimed to develop a set of evaluation criteria for English learning websites. These criteria can assist English teachers/web designers in designing effective websites for their English courses and can also guide English learners in screening for appropriate and reliable websites to use in increasing their English ability. To fulfill our…

Screening for aberrant behavior in the nuclear industry

International Nuclear Information System (INIS)

Borofsky, G.L.

1987-01-01

This paper attempts to promote a fuller understanding of how psychological assessment procedures can be used to reduce the threat from aberrant behavior in the nuclear industry. It begins with a discussion of the scientifically based methods that are used by psychologists in constructing, scoring, and interpreting these procedures. This discussion includes an emphasis on the concepts of validity and reliability and their central importance when one is choosing specific psychological screening tools. Criteria for selecting and using psychological assessment procedures when screening for aberrant behavior are also provided. Some commonly used assessment procedures that satisfy these criteria are discussed. A number a psychological assessment procedures specifically recommended for use in screening for aberrant behavior in the nuclear industry are described

Geological and Geochemical Criteria for the Estimation of the Area of The Lesser Hinggan for the Endogenous Gold Mineralization (The Far East, Russia)

Science.gov (United States)

Yurchenko, Yuriy

2015-04-01

The Area of the Lesser Hinggan in the middle of the XIX century has been known as one of the Gold areas of the Far East. Exploration of gold in different years were engaged by P.K. Yavorovskiy (1904), E.E. Anert (1928), G.V. Itsikson (1961), V.A. Buryak (1999, 2002, 2003), A.M. Zhirnov (1998, 2000, 2008), L.V. Eyrish (1960, 1964, 1995, 1999, 2002, 2008) and many others. But despite the abundance of factual materials in the problem of the gold metallogeny of the Lesser Hinggan are more aspects that still have not received a answer. Among them is the key issue about indigenous sources of the gold. First for the Lesser Hinggan area, structural-geochemical zoning at 1:200 000 scale was carried out based on the results of the precise analyses of over 2,600 soil and sediment stream samples. Three anomalous geochemical zones and nine anomalous geochemical clusters in their contours specialized for gold mineralization were revealed. Regional clarkes (fersms) for 19 chemical elements were calculated. Geological formations geochemically specialized for gold and their role in endogenous ore-forming processes were defined. Geochemical criteria for endogenous gold mineralization and its ore-formational affiliation were defined as well. Thus, from the geological and geochemical data, are the following signs of the gold mineralization of the Lesser Hinggan: 1. Some geological formations are geochemical specialized by the gold (carbon ("black") schists and ferruginous quartzite Vendian-Cambrian Hinggan series). They're considered as a source of the gold, involved in younger epigenetic processes of mobilization and redistribution of this element; 2. Contrasting geochemical anomalies of the gold and elements satellites in the secondary halos and stream sediments displayed in the contours of the geological formations of a wide age range - terrigenous-carbonate rocks of the Hinggan series, the Paleozoic granitoid massives, the Cretaceous volcanic fields ; 3. Samples of the native gold

Study on remote sensing geologic information of uranium metallogeny in western Liaoning-northern Hebei region

International Nuclear Information System (INIS)

Yu Baoshan

1998-01-01

Based on the study on geologic metallogenic environment, temporal and spatial distribution and deposit features of uranium deposits in western Liaoning-northern Hebei region, summarizing mainly remote sensing information and synthesizing geologic, geophysical and geochemical as well as hydrological data, the author has implemented all-region joint-quadrangle analysis, composite mapping and applications, set up interpretation criteria for circular and arcuate structures of different lithological areas, and then expounded their geologic meaning. Volcanic apparatuses, small close sedimentary basins and magmatic rockbodies closely associated with uranium mineralizations, especially the altitude and types of ore-controlling structures and mineralized alteration zones have been interpreted. 'Heat halo spot' has also been interpreted on the satellite image and its geologic meaning and relation to uranium metallization have been discussed. Finally, remote sensing geologic prospecting model and comprehensive prediction model have been established

Water quality criteria for hexachloroethane: Final report

Energy Technology Data Exchange (ETDEWEB)

Davidson, K.A.; Hovatter, P.S.; Ross, R.H.

1988-03-01

The available data regarding the environmental fate, aquatic toxicity, and mammalian toxicity of hexachloroethane, which is used in military screening smokes, were reviewed. The USEPA guidelines were used to generate water quality criteria for the protection of aquatic life and its uses and of human health. 16 tabs.

Population newborn screening for inherited metabolic disease: current UK perspectives.

Science.gov (United States)

Green, A; Pollitt, R J

1999-06-01

Some of the generally accepted criteria for screening programmes are inappropriate for newborn metabolic screening as they ignore the family dimension and the importance of timely genetic information. Uncritical application of such criteria creates special difficulties for screening by tandem mass spectrometry, which can detect a range diseases with widely different natural histories and responsiveness to treatment. Further difficulties arise from increasing demands for direct proof of the effects of screening on long-term morbidity and mortality. The randomized controlled trial is held to be the gold standard, but for ethical and practical reasons it will be impossible to achieve for such relatively rare diseases. This approach also oversimplifies the complex matrix of costs and benefits of newborn metabolic screening. A more workable approach could involve Bayesian synthesis, combining quantitative performance data from carefully designed prospective pilot studies of screening with existing experience of the natural history, diagnosis, and management of the individual disorders concerned.

14 CFR 1214.504 - Screening requirements.

Science.gov (United States)

2010-01-01

... Critical Space System Personnel Reliability Program § 1214.504 Screening requirements. (a) Only those... using evaluation guidance and criteria contained in Federal Personnel Manual (FPM) chapter 731 and...

Malignant transformation in vitro: criteria, biological markers, and application in environmental screening of carcinogens

International Nuclear Information System (INIS)

Borek, C.

1979-01-01

Biological markers which distinguish malignantly transformed fibroblasts from their normal counterpart include pleomorphic morphology, lowered requirement for nutritional factors, loss of density inhibition of growth, complex topography as discernible by scanning electron microscopy, loss in surface proteins, incomplete glycosylation of membrane glycolylipids and glycoproteins, increased production of specific proteases, decreased organization of the cytoskeleton, and acquisition of neoantigens. Several of these markers are not consistently found in transformed epithelial cells and therefore cannot serve to distinguish unequivocally neoplastic epithelial cells from the normal counterparts. The only criteria associated with the transformed nature of both fibroblasts and epithelial cells are the ability of the cells to proliferate in semisolid medium and to induce tumors in appropriate hosts. In vitro systems represent a powerful tool for screening the mutagenic/oncogenic potential of physical, chemical, and environmental agents. Fibroblasts rather than epithelial cells are preferred for this purpose at the present time because of the clear-cut phenotypic differences between the normal and the transformed cells. These systems have been useful in establishing that malignant transformation can be induced by doses as low as 1 rad of X rays or 0.1 rad of neutrons, and that fractionation at low dose levelsleads to enhanced transformation. They have been useful in identifying a large number of hazardous chemicals and in evaluating the relationship between the mutagenic and carcinogenic potential of radiation and chemicals

Scientific basis to assess the potential for geological sequestration of CO{sub 2} in Switzerland

Energy Technology Data Exchange (ETDEWEB)

Diamond, L. W.; Chevalier, G. [Institut fuer Geologie, Universitaet Bern, Bern (Switzerland); Leu, W. [Geoform AG, Geologische Beratungen und Studien, Villeneuve (former Minusio) (Switzerland)

2010-07-01

Possibilities to sequester anthropogenic CO{sub 2} in deep geological formations are being investigated worldwide, but the potential within Switzerland has not yet been evaluated. This study presents a first-order appraisal based solely on geological criteria collated from the literature. The Swiss Molasse Basin (SMB) and the adjacent Folded Jura are the only realms of the country where CO{sub 2} could conceivably be stored in saline aquifers. Evaluation of geological criteria at the basin-wide scale shows that the SMB-Jura has moderate potential (score of 0.6 on a scale from 0 to 1) when compared to basins elsewhere. At the intrabasinal scale, inspection of the stratigraphy reveals four regional candidate aquifers that are sealed by suitable caprocks: top Basement plus basal Mesozoic sandstones, all sealed by the Anhydrite Group; Upper Muschelkalk sealed by the Gipskeuper; Hauptrogenstein sealed by the Effinger Member, and Upper Malm plus Lower Cretaceous sealed by the Lower Freshwater Molasse. Nine geological criteria are defined to evaluate the storage potential of these and other smaller-scale candidates. A numerical scoring and weighting scheme allows the criteria to be assessed simultaneously, permitting the storage potential to be depicted using the 0-1 scale in contoured maps. Approximately 5000 km{sup 2} of the central SMB exhibits potentials between 0.6 and 0.96. The Fribourg-Olten-Lucerne area is the most favoured owing to the presence of several sealed aquifers within the preferred 800-2500 m depth interval, and to its low seismicity, low geothermal gradient, low fault density, and long groundwater residence times. Smaller areas with good potential lie between Zurich and St. Gall. In contrast, western Switzerland, the Jura and the southern SMB have markedly poorer potential. Considering only the portions of the aquifers with potential above 0.6, the theoretical, effective storage capacity of the basin is estimated to be 2680 million tonnes of CO{sub 2

The part played by applied geology in nuclear power plant site studies

International Nuclear Information System (INIS)

Giafferi, J.L.

1994-01-01

Site-related geological problems are one of the constraints affecting the environment of nuclear power plants. The natural features (soil and subsoil) at the nuclear power plant site affect numerous factors in the design, construction and operation of the civil engineering structures. The site geological criteria are not solely restricted to the soil as a static support for the structures. Earth tremors in France are of moderate intensity but the likelihood of their occurrence must nevertheless be taken into account for each site. Studies must concern the geological and seismic features of the region as well as the soil and subsoil configurations and composition in the immediate vicinity of the site in order to determine the physical characteristics of the earthquakes so that the safety of the plant can be guaranteed; in many cases, water tables have also to be taken into consideration. Geologic survey techniques are discussed. 13 figs., 7 refs

Prevalence of HIV positive blood donors among screened ...

African Journals Online (AJOL)

hope&shola

2006-04-03

Apr 3, 2006 ... Department of Physiology, Obafemi Awolowo College of Health Sciences, Olabisi Onabanjo University Teaching. Hospital ... screening volunteer donors by initial criteria alone does not fully eliminate all HIV positive donors. The prevalence of HIV ... HIV test criteria alone to qualify for blood donation in the.

Assessing screening criteria for the radiocarbon dating of bone mineral

Energy Technology Data Exchange (ETDEWEB)

Fernandes, Ricardo, E-mail: ldv1452@gmail.com [Leibniz Labor for Isotopic and Radiometric Dating, Max-Eyth-Str. 11-13, 24118 Kiel (Germany); Graduate School Human Development in Landscapes, Christian Albrecht University, Kiel (Germany); Huels, Matthias [Leibniz Labor for Isotopic and Radiometric Dating, Max-Eyth-Str. 11-13, 24118 Kiel (Germany); Nadeau, Marie-Josee; Grootes, Pieter M. [Leibniz Labor for Isotopic and Radiometric Dating, Max-Eyth-Str. 11-13, 24118 Kiel (Germany); Graduate School Human Development in Landscapes, Christian Albrecht University, Kiel (Germany); Garbe-Schoenberg, C.-Dieter [Institute of Geosciences, Marine Climate Research and ICPMS Lab, Kiel University, Ludewig-Meyn-Str. 10, D-24118 Kiel (Germany); Graduate School Human Development in Landscapes, Christian Albrecht University, Kiel (Germany); Hollund, Hege I. [Institute for Geo- and Bioarchaeology, The VU University, De Boelelaan 1085, 1081 HV Amsterdam (Netherlands); Lotnyk, Andriy [Faculty of Engineering, Institute for Material Science, Synthesis and Real Structure, Kiel University, Kaiserstr. 2, D-24143 Kiel (Germany); Leibniz Institute of Surface Modification (IOM), Permoserstr. 15, D-04318 Leipzig (Germany); Kienle, Lorenz [Faculty of Engineering, Institute for Material Science, Synthesis and Real Structure, Kiel University, Kaiserstr. 2, D-24143 Kiel (Germany); Graduate School Human Development in Landscapes, Christian Albrecht University, Kiel (Germany)

2013-01-15

Radiocarbon dating of bone mineral (carbonate in the apatite lattice) has been the target of sporadic research for the last 40 years. Results obtained by different decontamination protocols have, however, failed to provide a consistent agreement with reference ages. In particular, quality criteria to assess bone mineral radiocarbon dating reliability are still lacking. Systematic research was undertaken to identify optimal preservation criteria for bone mineral in archeological bones. Six human long bones, originating from a single site, were radiocarbon-dated both for collagen and apatite, with the level of agreement between the dates providing an indication of exogenous carbon contamination. Several techniques (Histology, FTIR, TEM, LA-ICP-MS) were employed to determine the preservation status of each sample. Research results highlight the importance of a micro-scale approach in establishing bone preservation, in particular the use of trace element concentration profiles demonstrated its potential use as a viable sample selection criterion for bone carbonate radiocarbon dating.

On melting criteria for complex plasma

International Nuclear Information System (INIS)

Klumov, Boris A

2011-01-01

The present paper considers melting criteria for a plasma crystal discovered in dust plasma in 1994. Separate discussions are devoted to three-dimensional (3D) and two-dimensional (2D) systems. In the 3D case, melting criteria are derived based on the properties of local order in a system of microparticles. The order parameters are constructed from the cumulative distributions of the microparticle probability distributions as functions of various rotational invariants. The melting criteria proposed are constructed using static information on microparticle positions: a few snapshots of the system that allow for the determination of particle coordinates are enough to determine the phase state of the system. It is shown that criteria obtained in this way describe well the melting and premelting of 3D complex plasmas. In 2D systems, a system of microparticles interacting via a screened Coulomb (i.e., Debye-Hueckel or Yukawa) potential is considered as an example, using molecular dynamics simulations. A number of new order parameters characterizing the melting of 2D complex plasmas are proposed. The order parameters and melting criteria proposed for 2D and 3D complex plasmas can be applied to other systems as well. (methodological notes)

[Early diagnosis of HIV in Primary Care in Spain. Results of a pilot study based on targeted screening based on indicator conditions, behavioral criteria and region of origin].

Science.gov (United States)

Agustí, Cristina; Martín-Rabadán, María; Zarco, José; Aguado, Cristina; Carrillo, Ricard; Codinachs, Roger; Carmona, Jose Manuel; Casabona, Jordi

2018-03-01

To estimate the prevalence of HIV infection in patients diagnosed with an indicator condition (IC) for HIV and/or risk behavior for their acquisition and/or coming from high prevalence countries. To determine the acceptability and feasibility of offering HIV testing based on IC and behavioral and origin criteria in Primary Care (PC). Cross-sectional study in a convenience sample. Six PC centers in Spain. The inclusion criteria were: patients between 16 and 65years old who presented at least one of the proposed ICs and/or at least one of the proposed behavioral and/or origin criteria. A total of 388 patients participated. HIV serology was offered to all patients who met the inclusion criteria. Description of IC frequency, behavioral and origin criteria. Prevalence of HIV infection. Level of acceptability and feasibility of the HIV screening based on IC and behavioral and origin criteria. A total of 174 patients had an IC (44.84%). The most common behavioral criterion was: having unprotected sex at some time in life with people who did not know their HIV status (298; 76.8%). Four HIV+ patients (1.03%) were diagnosed. All had an IC and were men who had sex with men. The level of acceptability in PC was high. Offering HIV testing to patients with IC and behavioral criteria is feasible and effective in PC. Copyright © 2017 Elsevier España, S.L.U. All rights reserved.

Criteria for determining casing depth in Cerro Prieto

Energy Technology Data Exchange (ETDEWEB)

Olivas M., H.M.; Vaca S., J.M.E.

1982-08-10

On the basis of geological data obtained during drilling and its relation to electric logs, together with the problems that arose when drilling through formations until the production zone was reached, it is possible to establish the most suitable manner to line a well and thus formulate an optimum casings program. The main criteria to be taken into consideration in preparing such a program and its application in the drilling of wells programmed in Cerro Prieto to optimize and economize such drilling and achieve suitable techniques for well completion are presented. The criteria are based on the characteristics of the Cerro Prieto field and on casing design factors, as well as a experience gained during drilling in such a field.

33 CFR 148.707 - What type of criteria will be used in an environmental review and how will they be applied?

Science.gov (United States)

2010-07-01

...: GENERAL Environmental Review Criteria for Deepwater Ports § 148.707 What type of criteria will be used in... patterns; (3) The potential risks to a deepwater port from waves, winds, weather, and geological conditions... children from environmental health and safety risks. ...

Prevalence of type 2 diabetes mellitus and other abnormalities of carbohydrate metabolism depending on diagnostic criteria

Directory of Open Access Journals (Sweden)

Alexander Vasil'evich Dreval'

2010-03-01

Full Text Available Aim. To assess current criteria for type 2 diabetes mellitus. Materials and methods. This screening study involving 2,368 residents of two municipal districts of the Moscow region was designed to elucidate differencesin the prevalence of abnormalities of carbohydrate metabolism depending on diagnostic criteria (WHO and ADA. Results. The prevalence of early disorders of carbohydrate metabolism and DM2 among the adult population of Moscow region is 17,1 and 7,2 respectivelyusing WHO criteria and 40,0 and 5,9% by ADA criteria. Conclusion. Refusal to undergo OGTT during screening decreases detectability of early metabolic disorders by 28,8 and 6,1% using WHO and ADAcriteria respectively. When screening is aimed to diagnose DM2 alone, OGTT can be omitted in subjects with fasting plasma glucose level below4,7 mmol/l. If it is aimed to diagnose both DM2 and impaired glucose tolerance, OGTT is not needed in subjects with fasting plasma glucose levelbelow 4,2 mmol/l. The use of ?combined? diagnostic criteria (i.e. OGTT according to ADA, but not WHO significantly increases the prevalence ofmetabolic disorders from 24,9 to 48,8%.

Interim licensing criteria for physical protection of certain storage of spent fuel

International Nuclear Information System (INIS)

Dwyer, P.A.

1994-11-01

This document presents interim criteria to be used in the physical protection licensing of certain spent fuel storage installations. Installations that will be reviewed under this criteria are those that store power reactor spent fuel at decommissioned power reactor sites; independent spent fuel storage installations located outside of the owner controlled area of operating nuclear power reactors; monitored retrievable storage installations owned by the Department of Energy, designed and constructed specifically for the storage, of spent fuel; the proposed geologic repository operations area; or permanently shutdown power reactors still holding a Part 50 license. This criteria applies to both dry cask and pool storage. However, the criteria in this document does not apply to the storage of spent fuel within the owner-controlled area of operating nuclear power reactors

Sediment quality criteria: A review with recommendations for developing criteria for the Hanford Site

Energy Technology Data Exchange (ETDEWEB)

Driver, C.J.

1994-05-01

Criteria for determining the quality of liver sediment are necessary to ensure that concentrations of contaminants in aquatic systems are within acceptable limits for the protection of aquatic and human life. Such criteria should facilitate decision-making about remediation, handling, and disposal of contaminants. Several approaches to the development of sediment quality criteria (SQC) have been described and include both descriptive and numerical methods. However, no single method measures all impacts at all times to all organisms (U.S. EPA 1992b). The U.S. EPA`s interest is primarily in establishing chemically based, numerical SQC that are applicable nation-wide (Shea 1988). Of the approaches proposed for SQC development, only three are being considered for numerical SQC on a national level. These approaches include an Equilibrium Partitioning Approach, a site-specific method using bioassays (the Apparent Effects Threshold Approach), and an approach similar to EPA`s water quality criteria (Pavlou and Weston 1984). Although national (or even regional) criteria address a number of political, litigative, and engineering needs, some researchers feel that protection of benthic communities require site-specific, biologically based criteria (Baudo et al. 1990). This is particularly true for areas where complex mixtures of contaminants are present in sediments. Other scientifically valid and accepted procedures for freshwater SQC include a background concentration approach, methods using field or spiked bioassays, a screening level concentration approach, the Apparent Effects Threshold Approach, the Sediment Quality Triad, the International Joint Commission Sediment Assessment Strategy, and the National Status and Trends Program Approach. The various sediment assessment approaches are evaluated for application to the Hanford Reach and recommendations for Hanford Site sediment quality criteria are discussed.

Evaluation model of commercial geological exploration and mining development project and analysis of some technical problems in commercial negotiation

International Nuclear Information System (INIS)

Yao Zhenkai

2012-01-01

A composite evaluation model of commercial geological exploration and mining development project was discussed, this new model consists of polity-economy-technique (PET) synthetic evaluation sub-model and geology-mining-metallurgy (GMM) technique evaluation sub-model. Besides, some key technical problems in commercial negotiation, such as information screening, quoted price and analysis of deadline, were briefly analyzed. (author)

Workshop material for state review of USNRC site suitability criteria for high-level radioactive waste repositories

International Nuclear Information System (INIS)

1977-08-01

The Nuclear Regulatory Commission (NRC) is developing criteria on which to judge whether a proposed site for a geologic repository is suitable for disposal of high-level nuclear wastes. To aid in its analysis and assessment, NRC is planning three early independent reviews of the site suitability criteria development effort: a peer review by experts outside of NRC; a review by the National Academy of Sciences; and a review by State officials. This document has been prepared to aid workshop participants in understanding the Preliminary Site Suitability Criteria and to prepare them to contribute to an evaluation of those criteria

Objectives, standards and criteria for radioactive waste disposal in the European Community

International Nuclear Information System (INIS)

Orlowski, S.; Schaller, K.H.

1989-01-01

The present report, edited by a working group within the framework of the European Commission research programme on radioactive waste management and disposal, reviews the objectives, standards and criteria for radioactive waste disposal in the European Community with a view to identifying common features and differences in the regulatory frameworks of its Member States. Suggestions for possible harmonization are made. A few common general principles form the basis for legal and regulatory measures. These principles apply to and are discussed for the following: radiation protection (with the systems of dose limitation and control), ethical and sociological questions, environmental and natural resources protection, and nuclear safeguards. A description is given of the implementation of common principles, standards and requirements at Community level, in line with requirements laid down in the European Community Treaties, and in international conventions and recommendations. This is followed by a review of the implementation of basic criteria by national safety authorities. Regulatory measures and national policies, and the approaches used in devising criteria are discussed for both near-surface disposal of low-level waste, and for deep geological disposal of waste in continental geological formations. Finally, the roles and duties of the operators of radioactive waste facilities are reported. More detailed information on particular aspects is presented in the annexes

Semantics-informed cartography: the case of Piemonte Geological Map

Science.gov (United States)

Piana, Fabrizio; Lombardo, Vincenzo; Mimmo, Dario; Giardino, Marco; Fubelli, Giandomenico

2016-04-01

correlated through the whole region and described using the GeoSciML vocabularies. A hierarchical schema is provided for the Piemonte Geological Map that gives the parental relations between several orders of GeologicUnits referring to mostly recurring geological objects and main GeologicEvents, in a logical framework compliant with GeoSciML and INSPIRE data models. The classification criteria and the Hierarchy Schema used to define the GEOPiemonteMap Legend, as well as the intended meanings of the geological concepts used to achieve the overall classification schema, are explicitly described in several WikiGeo pages (implemented by "MediaWiki" open source software, https://www.mediawiki.org/wiki/MediaWiki). Moreover, a further step toward a formal classification of the contents (both data and interpretation) of the GEOPiemonteMap was triggered, by setting up an ontological framework, named "OntoGeonous", in order to achieve a thorough semantic characterization of the Map.

Translating DWPF design criteria into an engineered facility design

International Nuclear Information System (INIS)

Kemp, J.B.

1986-01-01

The Defense Waste Processing Facility (DWPF) takes radioactive defense waste sludge and the radioactive nuclides, cesium and strontium, from the salt solution, and incorporates them in borosilicate glass in stainless steel canisters, for subsequent disposal in a deep geologic repository. The facility was designed by Bechtel National, Inc. under a subcontract from E.I. DuPont de Nemurs and Co., the prime contractor for the Department of Energy, for the design, construction and commissioning of the plant. The design criteria were specified by the DuPont Company, based upon their extensive experience as designer, and operator since the early 1950's, of the existing Savannah River Plant facilities. Some of the design criteria imposed unusual or new requirements on the detailed design of the facilities. This paper describes some of these criteria, encompassing several engineering disciplines, and discusses the solutions and designs which were developed for the DWPF

Evaluation of seismic criteria used in design of INEL facilities

International Nuclear Information System (INIS)

Young, G.A.

1977-01-01

This report provides the results of an independent evaluation of seismic studies that were made to establish the seismic acceleration levels and the response spectra used in the design of vital facilities at Idaho National Engineering Laboratory. A comparison of the procedures used to define the seismic acceleration values and response spectra at INEL with the requirements of the Nuclear Regulatory Commission showed that additional geologic studies would probably be required in order to fulfill NRC regulations. Recommendations are made on justifiable changes in the acceleration values and response spectra used at INEL. The geologic, geophysical, and seismological studies needed to provide a better understanding of the tectonic processes in the Snake River plains and the surrounding region are identified. Both potential and historical acceleration values are evaluated on a probability basis to permit a risk assessment approach to the design of new facilities and facility modifications. Studies conducted to develop seismic criteria for the design of the Loss of Fluid Test reactor and the New Waste Calcining Facility were selected as typical examples of criteria development previously used in the design of INEL facilities

2012 American Geriatrics Society Beers criteria: enhanced applicability for detecting potentially inappropriate medications in European older adults? A comparison with the Screening Tool of Older Person's Potentially Inappropriate Prescriptions.

Science.gov (United States)

Blanco-Reina, Encarnación; Ariza-Zafra, Gabriel; Ocaña-Riola, Ricardo; León-Ortiz, Matilde

2014-07-01

To determine the prevalence of potentially inappropriate medications (PIMs) and related factors through a comparative analysis of the Screening Tool of Older Person's Potentially Inappropriate Prescriptions (STOPP), the 2003 Beers criteria, and the 2012 AGS update of the Beers criteria. Cross-sectional. Primary care. Community-dwelling persons aged 65 and older who live on the island of Lanzarote, Spain (N = 407). Sociodemographic characteristics; independence in activities of daily living; cognitive function; Geriatric Depression Scale; clinical diagnoses; and complete data on indication, dosage, and length of drug treatments. One thousand eight hundred seventh-two prescriptions were examined, and the rate of PIMs was assessed with the three criteria. The primary endpoint was the percentage of participants receiving at least one PIM. Multivariate logistic regression was used to examine the factors related to PIMs. Potentially inappropriate medications were present in 24.3%, 35.4%, and 44% of participants, according to the 2003 Beers criteria, STOPP, and 2012 Beers criteria, respectively. The profile of PIMs was also different (the most frequent being benzodiazepines in both Beers criteria lists and aspirin in the STOPP). The number of drugs was associated with risk of prescribing PIMs in all three models, as was the presence of a psychological disorder in the 2003 Beers criteria (odds ratio (OR) = 2.07, 95% confidence interval (CI) = 1.26-3.40) and the 2012 Beers criteria (OR = 2.91, 95% CI = 1.83-4.66). The kappa for degree of agreement between STOPP and the 2012 Beers criteria was 0.35 (95% CI = 0.25-0.44). The 2012 Beers criteria detected the highest number of PIMs, and given the scant overlapping with the STOPP criteria, the use of both tools may be seen as complementary. © 2014, Copyright the Authors Journal compilation © 2014, The American Geriatrics Society.

10 CFR 60.112 - Overall system performance objective for the geologic repository after permanent closure.

Science.gov (United States)

2010-01-01

... repository after permanent closure. 60.112 Section 60.112 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN GEOLOGIC REPOSITORIES Technical Criteria Performance... environment following permanent closure conform to such generally applicable environmental standards for...

Characteristics and suitability of waste dump sites in Owerri, Nigeria ...

African Journals Online (AJOL)

A five point criteria screening of the three major waste dumpsites in Owerri Municipality was identified, and a ranking procedure adopted to determine the suitability or otherwise of the dumpsites. The sites were screened and ranked hydro-geologically and geo-technically in order of suitable, moderately suitable, and not ...

Inappropriate prescribing in the older population: need for new criteria.

LENUS (Irish Health Repository)

O'Mahony, Denis

2012-02-03

Inappropriate prescribing (IP) is a common and serious global healthcare problem in elderly people, leading to increased risk of adverse drug reactions (ADRs), polypharmacy being the main risk factor for both IP and ADRs. IP in older people is highly prevalent but preventable; hence screening tools for IP have been devised, principally Beers\\' Criteria and the Inappropriate Prescribing in the Elderly Tool (IPET). Although Beers\\' Criteria have become the most widely cited IP criteria in the literature, nevertheless, they have serious deficiencies, including several drugs that are rarely prescribed nowadays, a lack of structure in the presentation of the criteria and omission of several important and common IP instances. New, more up-to-date, systems-based and easily applicable criteria are needed that can be applied in the routine clinical setting.

Genetic and geological classification wetlands proposed. Application to the spanish wetlands included in the Ramsar convention; Propuesta de clasificacion genetico-geologica de humedales. Aplicacion a los humedales espanoles incluidos en el Convenio de Ramsar

Energy Technology Data Exchange (ETDEWEB)

Duran Valsero, J. J.; Garcia de Domingo, A.; Robledo Ardila, P.

2009-07-01

The classification represents the first step in the research of the wetlands. There are several types of classifications established according different criteria: geographic, genetic, geologic, functional, hydric, biologic and others. In this work we considered the genetic and geologic classifications criteria are the more suitable because the criteria used are very concrete, descriptive and its application should be easier to put into practice. Every group established in this type of classification determines the develop naturals conditions allowing us to establish the evolution guidelines and same main management lines. The criteria used to develop this classification have been fundamentally: geologic, geomorphologic, tectonics, stratigraphic, and hydrogeologic because these determine greatly the physical wetland characteristics (geometric parameters, hydric nourishment system, hydrochemical characteristics and others). The general characteristics, guidelines behavior of the wetland, and the early evolution of every group of wetland could be essentials to detect and identified those actuations modifying the natural evolution in each concrete wetland. In this work we are applying these classification criteria to the Spanish wetlands included in the Ramsar Convention (until February 2006), defining twelve types of basic wetlands according the geologic and genetic characteristics. (Author) 19 refs.

Prevalence of HIV positive blood donors among screened ...

African Journals Online (AJOL)

Two thousand five hundred and thirty two (2,532) males, aged 25 – 50 years potential blood donors were randomly selected from the total number of volunteer blood donors who satisfied the initial screening criteria for donating blood, and were screened for HIV using Immunocomb II (HIV 1 and 2 Bispot) and Recombigen ...

California Geological Survey Geologic Map Index

Data.gov (United States)

California Natural Resource Agency — All the individual maps from the Geologic Atlas of California and the Regional Geologic map series have been georeferenced for display in a GIS (and viewable online...

10 CFR Appendix A to Part 100 - Seismic and Geologic Siting Criteria for Nuclear Power Plants

Science.gov (United States)

2010-01-01

... materials has occurred parallel to the fracture plane. It is distinct from other types of ground disruptions... history; (2) Identification and evaluation of tectonic structures underlying the site and the region... in order to permit appropriate consideration of the geologic history of such faults in establishing...

Screening for Internet dependence: do the proposed diagnostic criteria differentiate normal from dependent Internet use?

Science.gov (United States)

Dowling, Nicki A; Quirk, Kelly L

2009-02-01

There is continued discussion of including Internet dependence as a diagnosis in future editions of the Diagnostic and Statistical Manual of Mental Disorders. The primary aim of the study was to evaluate the utility of the proposed diagnostic criteria for Internet dependence as measured by Young's Diagnostic Questionnaire (YDQ). Although the YDQ does not provide any measure of severity, there is emerging recognition that some Internet users may display less severe or at risk Internet dependence. The degree to which the cutoff of 5 out of 8 criteria is appropriate to differentiate nondependent from dependent Internet use was evaluated by comparing the Internet usage and psychological dysfunction of 424 university students endorsing 3 and 4 diagnostic criteria (at-risk Internet dependence) to those endorsing less than 3 criteria (nondependent) and those endorsing 5 or more criteria (Internet dependence). The findings suggest that the proposed diagnostic criteria do not adequately discriminate individuals scoring 3 or 4 from those currently classified as Internet dependent. The implications of the findings for the assessment, diagnosis, and treatment of Internet dependence are discussed.

Design criteria development for the structural stability of nuclear waste repository

Energy Technology Data Exchange (ETDEWEB)

Yun, C H [Korea Institute of Nuclear Safety, Taejon (Korea, Republic of); Yu, T S [Daewoo Engineering Company, Sungnam (Korea, Republic of); Ko, H M [Seoul National Univ., Seoul (Korea, Republic of)

1990-11-15

The objective of the present project is to develop design criteria for the structural stability of rock cavity for the underground repository are defined, according to which detailed descriptions for design methodologies, design stages and stability analysis of the cavity are made. The proposed criteria can be used as a guide for the preparation of design codes which are to be established as the site condition and technical emplacement procedure are fixed. The present report first reviews basic safety requirements and criteria of the underground disposal of nuclear wastes for the establishment of design concepts and stability analysis of the rock cavity. Important factors for the design are also described by considering characteristics of the wastes and underground facilities. The present project has investigated technical aspects on the design of underground structures based on the currently established underground construction technologies, and presented a proposal for design criteria for the structural stability of the nuclear waste repository. The proposed criteria consist of general provisions, geological exploration, rock classification, design process and methods, supporting system, analyses and instrumentation.

Aspects of sismo-tectonic stability in the South-Eastern region of Brazil of interest to geology of engineering

International Nuclear Information System (INIS)

Mioto, J.A.; Hasui, Y.

1982-01-01

The occurence of earthquakes in Brazil, mainly in the South-eastern region, and its relationship with the geologic features has been discussed by many Authors since the beginning of this Century. It is difficult to define intraplate seismicity and to understand the actual epirogenic displacent, but the definition of the regional stability is important for enginnering purposes and have been considered through seismologic, morphotectonic and geologic criteria. (Author) [pt

STOPP (Screening Tool of Older Person's Prescriptions) and START (Screening Tool to Alert doctors to Right Treatment). Consensus validation.

LENUS (Irish Health Repository)

Gallagher, P

2012-02-03

OBJECTIVE: Older people experience more concurrent illnesses, are prescribed more medications and suffer more adverse drug events than younger people. Many drugs predispose older people to adverse events such as falls and cognitive impairment, thus increasing morbidity and health resource utilization. At the same time, older people are often denied potentially beneficial, clinically indicated medications without a valid reason. We aimed to validate a new screening tool of older persons\\' prescriptions incorporating criteria for potentially inappropriate drugs called STOPP (Screening Tool of Older Persons\\' Prescriptions) and criteria for potentially appropriate, indicated drugs called START (Screening Tool to Alert doctors to Right, i.e. appropriate, indicated Treatment). METHODS: A Delphi consensus technique was used to establish the content validity of STOPP\\/START. An 18-member expert panel from academic centers in Ireland and the United Kingdom completed two rounds of the Delphi process by mail survey. Inter-rater reliability was assessed by determining the kappa-statistic for measure of agreement on 100 data-sets. RESULTS: STOPP is comprised of 65 clinically significant criteria for potentially inappropriate prescribing in older people. Each criterion is accompanied by a concise explanation as to why the prescribing practice is potentially inappropriate. START consists of 22 evidence-based prescribing indicators for commonly encountered diseases in older people. Inter-rater reliability is favorable with a kappa-coefficient of 0.75 for STOPP and 0.68 for START. CONCLUSION: STOPP\\/START is a valid, reliable and comprehensive screening tool that enables the prescribing physician to appraise an older patient\\'s prescription drugs in the context of his\\/her concurrent diagnoses.

Redesigning Curricula in Geology and Geophysics

Science.gov (United States)

Sparks, D. W.; Ewing, R. C.; Fowler, D.; Macik, M.; Marcantonio, F.; Miller, B.; Newman, J.; Olszewski, T.; Reece, R.; Rosser, S.

2015-12-01

In the summer of 2014, the Texas A&M Department of Geology and Geophysics partnered with the Texas A&M Center for Teaching Excellence to implement TAMU's curriculum revision process: a data-informed, faculty-driven, educational-developer-supported rebuilding of our degree programs and course offerings. The current curricula (B.S. and B.A. in Geology, B.S. in Geophysics) were put into place in 1997, following the merger of two separate departments. The needs and capabilities of the Department and the student body have changed significantly since that time: more than 50% turnover of the faculty, a rapidly-changing job climate for geologists and geophysicists, and a nearly five-fold increase in the undergraduate population to over 500 majors in Fall 2015. Surveys of former students, employers and faculty at other universities revealed more reasons to address the curriculum. Some of the most desired skills are also those at which our graduates feel and are perceived to be least prepared: oral communication and the ability to learn software packages (skills that are most challenging to teach with growing class sizes). The challenge facing the Department is to accommodate growing student numbers while maintaining strength in traditional instructor-intensive activities such as microscopy and field mapping, and also improving our graduates' non-geological skills (e.g., communication, software use, teamwork, problem-solving) to insulate them from volatility in the current job market. We formed the Curriculum Study Group, consisting of faculty, graduate students, advisors and curriculum experts, to gather and analyze data and define the knowledge and skill base a graduate of our department must have. In addition to conducting external surveys, this group interviewed current students and faculty to determine the strengths and weaknesses of our program. We developed program learning goals that were further specified into over fifty criteria. For each criteria we defined

Limits on the thermal energy release from radioactive wastes in a mined geologic repository

International Nuclear Information System (INIS)

Scott, J.A.

1983-03-01

The theraml energy release of nuclear wastes is a major factor in the design of geologic repositories. Thermal limits need to be placed on various aspets of the geologic waste disposal system to avoid or retard the degradation of repository performance because of increased temperatures. The thermal limits in current use today are summarized in this report. These limits are placed in a hierarchial structure of thermal criteria consistent with the failure mechanism they are trying to prevent. The thermal criteria hierarchy is used to evaluate the thermal performance of a sample repository design. The design consists of disassembled BWR spent fuel, aged 10 years, close packed in a carbon steel canister with 15 cm of crushed salt backfill. The medium is bedded salt. The most-restrictive temperature for this design is the spent-fuel centerline temperature limit of 300 0 C. A sensitivity study on the effects of additional cooling prior to disposal on repository thermal limits and design is performed

The Berlin Inventory of Gambling behavior - Screening (BIG-S): Validation using a clinical sample.

Science.gov (United States)

Wejbera, Martin; Müller, Kai W; Becker, Jan; Beutel, Manfred E

2017-05-18

Published diagnostic questionnaires for gambling disorder in German are either based on DSM-III criteria or focus on aspects other than life time prevalence. This study was designed to assess the usability of the DSM-IV criteria based Berlin Inventory of Gambling Behavior Screening tool in a clinical sample and adapt it to DSM-5 criteria. In a sample of 432 patients presenting for behavioral addiction assessment at the University Medical Center Mainz, we checked the screening tool's results against clinical diagnosis and compared a subsample of n=300 clinically diagnosed gambling disorder patients with a comparison group of n=132. The BIG-S produced a sensitivity of 99.7% and a specificity of 96.2%. The instrument's unidimensionality and the diagnostic improvements of DSM-5 criteria were verified by exploratory and confirmatory factor analysis as well as receiver operating characteristic analysis. The BIG-S is a reliable and valid screening tool for gambling disorder and demonstrated its concise and comprehensible operationalization of current DSM-5 criteria in a clinical setting.

Breast cancer screening, outside the population-screening program, of women from breast cancer families without proven BRCA1/BRCA2 mutations : a simulation study

NARCIS (Netherlands)

Jacobi, C.E.; Nagelkerke, N.J.D.; van Houwelingen, J.C.; de Bock, G.H.

Purpose: We assessed the cost-effectiveness of mammography screening for women under the age of 50, from breast cancer families without proven BRCA1./BRCA2 mutations, because current criteria for screening healthy women from breast cancer families are not evidence-based. Methods: We did simulation

Breast cancer screening, outside the population-screening program, of women from breast cancer families without proven BRCA1/BRCA2 mutations: a simulation study

NARCIS (Netherlands)

Jacobi, C.E.; Nagelkerke, N.J.D.; van Houwelingen, J.C.; de Bock, Truuske

2006-01-01

Purpose: We assessed the cost-effectiveness of mammography screening for women under the age of 50, from breast cancer families without proven BRCA1./BRCA2 mutations, because current criteria for screening healthy women from breast cancer families are not evidence-based. Methods: We did simulation

Geological evolution of clay sediments: the petroleum exploration vision

International Nuclear Information System (INIS)

Schneider, F.

2004-01-01

The radioactive waste isolation capacity assessment for a clay sediment host rock is link: (1) to the understanding of their present state properties and 3-D repartition (from basin evolution, including sedimentary and diagenetic process); and (2) to the prediction of their future evolution during the next million years. For petroleum exploration, basin modelling aims at reconstructing the accumulation of hydrocarbons at basin scale, and at geological timescale, taking into account the effects of kinematics displacements, sedimentation, erosion, compaction, temperatures history, overpressures and fluids flows (water and hydrocarbons). Furthermore, explorationists wish to address overpressure reconstruction in order to estimate the risks of drilling. Clay sediments are of interest for petroleum exploration because source rocks and seal are generally composed of them. Nevertheless, in spite of their occurrence in nature their evolution at geological timescale is not well understood. And, most of the knowledge has been achieved by those working in the realms of soils mechanics and civil engineering until the present geological investigations for long term radioactive waste repositories. Application of this knowledge to clay sediment is considered to be valid within the first hundreds of meters at the top of the sedimentary pile, according to a repository depth. This paper is dedicated to the sedimentary rocks behaviour at geological timescale. This behaviour is characterised by: (1) the deposition of the sediment; (2) the loading path at geological timescale; (3) the constitutive law which includes the consolidation process and the rupture criteria; and (4) the parameters evolution related to consolidation. (author)

The development of international safety standards on geological disposal

International Nuclear Information System (INIS)

McCartin, T.

2005-01-01

The IAEA is developing a set of safety requirements for geologic disposal to be used by both developers and regulators for planning, designing, operating, and closing a geologic disposal facility. Safety requirements would include quantitative criteria for assessing safety of geologic disposal facilities as well as requirements for development of the facility and the safety strategy including the safety case. Geologic disposal facilities are anticipated to be developed over a period of at least a few decades. Key decisions, e.g., on the disposal concept, siting, design, operational management and closure, are expected to be made in a series of steps. Decisions will be made based on the information available at each step and the confidence that may be placed in that information. A safety strategy is important for ensuring that at each step during the development of the disposal facility, an adequate understanding of the safety implications of the available options is developed such that the ultimate goal of providing an acceptable level of operational and post closure safety will be met. A safety case for a geologic disposal facility would present all the safety relevant aspects of the site, the facility design and the managerial and regulatory controls. The safety case and its supporting assessments illustrates the level of protection provided and shall give reasonable assurance that safety standards will be met. Overall, the safety case provides confidence in the feasibility of implementing the disposal system as designed, convincing estimates of the performance of the disposal system and a reasonable assurance that safety standards will be met. (author)

Effectiveness of border screening for detecting influenza in arriving airline travelers.

Science.gov (United States)

Priest, Patricia C; Jennings, Lance C; Duncan, Alasdair R; Brunton, Cheryl R; Baker, Michael G

2015-10-01

We measured symptom and influenza prevalence, and the effectiveness of symptom and temperature screening for identifying influenza, in arriving international airline travelers. This cross-sectional study collected data from travelers to Christchurch International Airport, New Zealand, in winter 2008, via a health questionnaire, temperature testing, and respiratory sampling. Forms were returned by 15 976 (68%) travelers. Of these, 17% reported at least 1 influenza symptom, with runny or blocked nose (10%) and cough (8%) most common. Respiratory specimens were obtained from 3769 travelers. Estimated prevalence of influenza was 1.1% (4% among symptomatic, 0.2% among asymptomatic). The sensitivity of screening criteria ranged from 84% for "any symptom" to 3% for a fever of 37.8 °C or greater. The positive predictive value was low for all criteria. Border screening using self-reported symptoms and temperature testing has limitations for preventing pandemic influenza from entering a country. Using "any symptom" or cough would lead to many uninfected people being investigated, yet some infected people would remain undetected. If more specific criteria such as fever were used, most infected people would enter the country despite screening.

[Effectiveness of border screening for detecting Influenza in arriving airline travelers].

Science.gov (United States)

Priest, Patricia C; Jennings, Lance C; Duncan, Alasdair R; Brunton, Cheryl R; Baker, Michael G

2014-02-01

We measured symptom and influenza prevalence, and the effectiveness of symptom and temperature screening for identifying influenza, in arriving international airline travelers. This cross-sectional study collected data from travelers to Christchurch International Airport, New Zealand, in winter 2008, via a health questionnaire, temperature testing, and respiratory sampling. Forms were returned by 15 976 (68%) travelers. Of these, 17% reported at least 1 influenza symptom, with runny or blocked nose (10%) and cough (8%) most common. Respiratory specimens were obtained from 3769 travelers. Estimated prevalence of influenza was 1.1% (4% among symptomatic, 0.2% among asymptomatic). The sensitivity of screening criteria ranged from 84% for "any symptom" to 3% for a fever of 37.8 ºC or greater. The positive predictive value was low for all criteria. Border screening using self-reported symptoms and temperature testing has limitations for preventing pandemic influenza from entering a country. Using "any symptom" or cough would lead to many uninfected people being investigated, yet some infected people would remain undetected. If more specific criteria such as fever were used, most infected people would enter the country despite screening.

Assessment of hydrogen fuel cell applications using fuzzy multiple-criteria decision making method

International Nuclear Information System (INIS)

Chang, Pao-Long; Hsu, Chiung-Wen; Lin, Chiu-Yue

2012-01-01

Highlights: ► This study uses the fuzzy MCDM method to assess hydrogen fuel cell applications. ► We evaluate seven different hydrogen fuel cell applications based on 14 criteria. ► Results show that fuel cell backup power systems should be chosen for development in Taiwan. -- Abstract: Assessment is an essential process in framing government policy. It is critical to select the appropriate targets to meet the needs of national development. This study aimed to develop an assessment model for evaluating hydrogen fuel cell applications and thus provide a screening tool for decision makers. This model operates by selecting evaluation criteria, determining criteria weights, and assessing the performance of hydrogen fuel cell applications for each criterion. The fuzzy multiple-criteria decision making method was used to select the criteria and the preferred hydrogen fuel cell products based on information collected from a group of experts. Survey questionnaires were distributed to collect opinions from experts in different fields. After the survey, the criteria weights and a ranking of alternatives were obtained. The study first defined the evaluation criteria in terms of the stakeholders, so that comprehensive influence criteria could be identified. These criteria were then classified as environmental, technological, economic, or social to indicate the purpose of each criterion in the assessment process. The selected criteria included 14 indicators, such as energy efficiency and CO 2 emissions, as well as seven hydrogen fuel cell applications, such as forklifts and backup power systems. The results show that fuel cell backup power systems rank the highest, followed by household fuel cell electric-heat composite systems. The model provides a screening tool for decision makers to select hydrogen-related applications.

Mixed total screening for sulfur isotope

International Nuclear Information System (INIS)

Cui Bin; Zhao Lei; Zhan Zhaoyang; He Zhijun

2003-01-01

The research on modern economic geology indicates that most ore deposits formed with characters of multi-origin, multi-stage and multi-genesis. Quantificational research of Sulfur isotope origin is a difficult problem that puzzles Geochemists all along. So the formation process of an ore deposit can be taken as the mix or the superposition of multi totals, which can be described by the mathematics model of mixed total screening. In the study of mid-down Yangtze River and Dongpo ore field in Hunan province, the authors successfully applied the mathematics model of mixed total screening, quantificationally resolved the problem of Sulfur isotope origin and mineralizing matter origin, and found out the mineralizing mechanism. This is very valuable. (authors)

The validity of the Michigan Alcoholism Screening Test (MAST)

DEFF Research Database (Denmark)

Storgaard, H; Nielsen, S D; Gluud, C

1994-01-01

This review examines the validity of the Michigan Alcoholism Screening Test (MAST) as a screening instrument for alcohol problems. Studies that compare the MAST-questionnaire with other defined diagnostic criteria of alcohol problems were retrieved through MEDLINE and a cross-bibliographic check....... A total of 20 validity studies were included. The studies varied considerably regarding the prevalence of alcohol problems, the diagnostic criteria, and the examined patient categories. The MAST compared with other diagnostic criteria of alcohol problems gave validity measures with the following span...... and the specificities show substantial variations. The variables that seem to have the largest influence on the PVpos seem to be the prevalence of alcohol problems, the diagnostic method against which the MAST-questionnaire is validated, and the populations on which the MAST is applied. The MAST should in the future...

Site characterization criteria (DOE-STD-1022-94) for natural phenomena hazards at DOE sites

International Nuclear Information System (INIS)

Chen, J.C.; Ueng, T.S.; Boissonnade, A.C.

1995-12-01

This paper briefly summarizes requirements of site characterization for Natural Phenomena Hazards (NPH) at DOE sites. In order to comply with DOE Order 5480.28, site characterization criteria has been developed to provide site-specific information needed for development of NPH assessment criteria. Appropriate approaches are outlined to ensure that the current state-of-the-art methodologies and procedures are used in the site characterization. General and detailed site characterization requirements are provided in the areas of meteorology, hydrology, geology, seismology and geotechnical studies

Synthetic geology - Exploring the "what if?" in geology

Science.gov (United States)

Klump, J. F.; Robertson, J.

2015-12-01

The spatial and temporal extent of geological phenomena makes experiments in geology difficult to conduct, if not entirely impossible and collection of data is laborious and expensive - so expensive that most of the time we cannot test a hypothesis. The aim, in many cases, is to gather enough data to build a predictive geological model. Even in a mine, where data are abundant, a model remains incomplete because the information at the level of a blasting block is two orders of magnitude larger than the sample from a drill core, and we have to take measurement errors into account. So, what confidence can we have in a model based on sparse data, uncertainties and measurement error? Synthetic geology does not attempt to model the real world in terms of geological processes with all their uncertainties, rather it offers an artificial geological data source with fully known properties. On the basis of this artificial geology, we can simulate geological sampling by established or future technologies to study the resulting dataset. Conducting these experiments in silico removes the constraints of testing in the field or in production, and provides us with a known ground-truth against which the steps in a data analysis and integration workflow can be validated.Real-time simulation of data sources can be used to investigate crucial questions such as the potential information gain from future sensing capabilities, or from new sampling strategies, or the combination of both, and it enables us to test many "what if?" questions, both in geology and in data engineering. What would we be able to see if we could obtain data at higher resolution? How would real-time data analysis change sampling strategies? Does our data infrastructure handle many new real-time data streams? What feature engineering can be deducted for machine learning approaches? By providing a 'data sandbox' able to scale to realistic geological scenarios we hope to start answering some of these questions.

Photo screening around the world: Lions Club International Foundation experience.

Science.gov (United States)

Donahue, Sean P; Lorenz, Sylvia; Johnson, Tammy

2008-01-01

To describe the use of photoscreening for preschool vision screening in several diverse locations throughout the world. The MTI photo screener was used to screen pre-verbal children; photographs were interpreted using standard criteria. The Tennessee vision screening program remains successful, screening over 200,000 children during the past 8 years. Similar programs modeled across the United States have screened an additional 500,000 children. A pilot demonstration project in Hong Kong, Beijing, and Brazil screened over 5000 additional children with good success and appropriately low referral rates. Photoscreening can be an appropriate technique for widespread vision screening of preschool children throughout the world.

Multi-criteria evaluation of natural gas resources

International Nuclear Information System (INIS)

Afgan, Naim H.; Pilavachi, Petros A.; Carvalho, Maria G.

2007-01-01

Geologically estimated natural gas resources are 500 Tcm. With the advance in geological science increase of estimated resources is expected. Natural gas reserves in 2000 have been proved to be around 165 Tcm. As it is known the reserves are subject to two constraints, namely: capital invested in the exploration and drilling technologies used to discover new reserves. The natural gas scarcity factor, i.e. ratio between available reserves and natural gas consumption, is around 300 years for the last 50 years. The new discovery of natural gas reserves has given rise to a new energy strategy based on natural gas. Natural gas utilization is constantly increasing in the last 50 years. With new technologies for deep drilling, we have come to know that there are enormous gas resources available at relatively low price. These new discoveries together with high demand for the environment saving have introduced a new energy strategy on the world scale. This paper presents an evaluation of the potential natural gas utilization in energy sector. As the criteria in this analysis resource, economic, environmental, social and technological indicators are used. Among the potential options of gas utilization following systems are considered: Gas turbine power plant, combine cycle plant, CHP power plant, steam turbine gas-fired power plant, fuel cells power plant. Multi-criteria method was used for the assessment of potential options with priority given to the Resource, Economic and Social Indicators. Results obtained are presented in graphical form representing priority list of potential options under specific constraints in the priority of natural gas utilization strategy in energy sector

Geologic siting considerations for the disposal of radioactive waste into submarine geologic formations

International Nuclear Information System (INIS)

Hollister, C.D.

1979-01-01

The most desirable characteristics of the host medium are: (1) low permeability and high Kd; (2) ability to self heal, i.e., be visco-elastic in response to dynamic stress; (3) stability under predicted thermal loading; (4) a low content of organic matter, i.e., be well oxidized. The submarine geologic formation that appears to best satisfy the above criteria is abyssal red clay. Depending on organic interactions and permeability considerations, light brown deep-sea clays with 20 to 40% CaCO 3 also may be suitable. Increasingly organic-rich, more permeable biogenic oozes appear less suitable, with turbidite sands and silts least desirable of all. Ocean regions excluded at the present time are: (1) areas less than 4000 meters deep; (2) the continental margin including fans, deltas, aprons, cones; (3) proximal portions of abyssal plains; (4) all fracture zone abyssal plains; (5) all submarine canyon-levee systems; (6) areas covered with less than 50 meters of sediment; (7) areas greater than 100 nautical miles from plate boundaries; (8) areas with ice-rafted debris; (9) major shipping lanes, cable routes and defense installations; (10) seafloor regions below areas of high biological productivity; and (11) approximately one third of the world's ocean floor satisfy these criteria

Engineering study of generic site criteria for selected DOE plutonium facilities

International Nuclear Information System (INIS)

Kingsbury, R.J.; Greenwood, J.M.; Sandoval, M.D.

1980-09-01

The objectives of this study were to identify criteria that would be applied to selection of a site for plutonium facilities such as those at the Rocky Flats Plant, to establish the relative importance of these criteria, and to identify suitable areas within the United States for location of plutonium facilities with respect to these criteria. Sources of the site criteria identified include federal laws, federal agency regulations, state laws and regulations, and requirements associated with operations to be performed at the site. The criteria identified during the study were organized into 14 major categories. The relative importnace of each category and each criterion within the categories were established using group decision-making techniques. The major criteria categories, their assigned weight on a scale of 1 to 10, and their relative priority ranks are as follows: geology/seismicity; public safety; environmental impact; meteorology; hydrology; topography; transportation; utilities; personnel; safeguards/security; land area and availability; land use compatibility; and, public acceptance. A suitability analysis of the continental United States was performed using only those criteria that could be mapped at a national scale. Suitability was assessed with respect to each of these criteria, and individual suitability maps were prepared. A composite suitability map was generated using computerized overlay techniques. This map provides a starting point for identifying specific candidate sites if an actual site selection were to be conducted

Subsurface arrangement constraints and selection criteria SOW, 4.5.1.2.1: Technical report, Revision 0

International Nuclear Information System (INIS)

1984-12-01

The United States Department of Energy has the responsibility to develop an underground geological repository for the storage and isolation of nuclear waste. This report identifies design constraints and subsurface arrangement selection criteria for the subsurface portion of a repository in salt. These criteria provide a base from which subsurface layout will be selected for approval by the Department of Energy. This document provides the basic criteria for the architect/engineer to select the subsurface layout. While this document does not address site-specific criteria, it does act as a guideline for subsurface design allowing for exploration of any reasonable option of that design. The criteria developed in this report address specific areas and concerns within a subsurface layout plan. The subsurface layout selection criteria were developed from industry standards, federal regulations, and quality assurance standards. 18 refs., 7 figs., 5 tabs

Evolution of waste-package design at the potential U.S. geologic repository

International Nuclear Information System (INIS)

Benton, H.; Harkins, B.

2000-01-01

This paper describes the evolution of the waste-package design at the potential geologic repository for spent nuclear fuel and high-level waste at Yucca Mountain in Nevada. Because the potential repository is the first of its kind, the design of its components must be flexible and capable of evolving in response to continuing scientific study, development efforts, and changes to performance criteria. The team of scientists and engineers at the Yucca Mountain Project has utilized a systematic, scientific approach to design the potential geologic nuclear-waste repository. As a result of continuing development efforts, the design has incorporated a growing base of scientific and engineering information to ensure that regulatory and performance requirements are met. (authors)

Criteria of transformation of object ''Ukryttya'' in environmentally safe system

International Nuclear Information System (INIS)

Batyij, V.G.; Jegorov, V.V.; Rud'ko, V.M.; Shcherbyin, V.M.

2015-01-01

The analysis of criteria of division of radioactive wastes (RAW) of object ''Ukryttya'' is executed on short-lived and long-lived, and their activity. It is shown that to short-lived RAW underactive belong and insignificant part of me-dium-activity waste. Hundreds of thousands of m3 of RAW on overhead marks belong to long-lived medium-activity wastes. Organization of burial place of such wastes in stable geological structures is an unrealistic task. It is suggested to create the special depository for such RAW, and buried in stable geological structures high-activity wastes only

Geology and occurrence of radon precursors

International Nuclear Information System (INIS)

Schmalz, R.F.

1990-01-01

The discovery that radioactive radon gas may occur as a significant indoor contaminant in houses and in the workplace has had far-reaching consequences in public health, real estate marketing, the construction industry, health and liability insurance underwriting, and in legislation at the federal and state levels. Many factors are known to affect radon level inside a building - its location, construction, ventilation, and substructure; the climate of the region in which it is located and the life styles of it occupants, for example. Despite the importance of assessing the hazard radon contamination may represent, the economic cost and the time required to screen hundreds of millions of individual buildings make such an effort impracticable. The effectiveness of large-scale regional screening to evaluate radon potential depends on an understanding of the chemical and physical properties of the gas, and of the geological and geochemical factors which control the distribution of its radioactive progenitors, radium, uranium and thorium. It is the purpose of this paper to review and summarize our present knowledge of these large-scale controls on radon occurrence

Covariance Based Pre-Filters and Screening Criteria for Conjunction Analysis

Science.gov (United States)

George, E., Chan, K.

2012-09-01

Several relationships are developed relating object size, initial covariance and range at closest approach to probability of collision. These relationships address the following questions: - Given the objects' initial covariance and combined hard body size, what is the maximum possible value of the probability of collision (Pc)? - Given the objects' initial covariance, what is the maximum combined hard body radius for which the probability of collision does not exceed the tolerance limit? - Given the objects' initial covariance and the combined hard body radius, what is the minimum miss distance for which the probability of collision does not exceed the tolerance limit? - Given the objects' initial covariance and the miss distance, what is the maximum combined hard body radius for which the probability of collision does not exceed the tolerance limit? The first relationship above allows the elimination of object pairs from conjunction analysis (CA) on the basis of the initial covariance and hard-body sizes of the objects. The application of this pre-filter to present day catalogs with estimated covariance results in the elimination of approximately 35% of object pairs as unable to ever conjunct with a probability of collision exceeding 1x10-6. Because Pc is directly proportional to object size and inversely proportional to covariance size, this pre-filter will have a significantly larger impact on future catalogs, which are expected to contain a much larger fraction of small debris tracked only by a limited subset of available sensors. This relationship also provides a mathematically rigorous basis for eliminating objects from analysis entirely based on element set age or quality - a practice commonly done by rough rules of thumb today. Further, these relations can be used to determine the required geometric screening radius for all objects. This analysis reveals the screening volumes for small objects are much larger than needed, while the screening volumes for

Neonatal intensive care unit-specific screening criteria for retinopathy of prematurity

Directory of Open Access Journals (Sweden)

Yu-Hung Lai

2012-11-01

Full Text Available This study investigated the incidence of retinopathy of prematurity (ROP and its risk factors in a tertiary referral hospital in Taiwan to evaluate the applicability of the ROP screening guidelines published by the American Academy of Pediatrics, American Academy of Ophthalmology, and American Association for Pediatric Ophthalmology and Strabismus in 2006 (2006 guidelines. A pediatric ophthalmologist applied the 2006 guidelines to screen for ROP and to treat with laser photocoagulation in each case. We retrieved all records of premature infants referred for ROP screening at the hospital during 2004 to 2008. Univariate logistic regression analysis was applied firstly to identify factors correlating with stage 3 ROP or with laser treatment, and then those significant (p < 0.05 risk factors were analyzed by multivariate logistic regression. In the 138 male and 118 female premature infants in this study, mean gestation age was 30.8 ± 2.8 weeks, and mean birth weight was 1464.7 ± 434.2 g. The percentage of infants with ROP in at least one eye was 38.7%. Thirty two (12.5% had ROP stage 3 or higher in at least one eye. Multivariate logistic regression analysis showed that the best predictors of type 1 pre-threshold ROP (requiring laser treatment were young gestational age, low birth weight and male gender. As medical care of extremely premature infants improves, timely identification and treatment of conditions such as ROP are essential. Although the incidence of ROP in this institute was comparable to that in developing countries and higher than that in developed countries, the 2006 guidelines originally developed for a United States population were still applicable. However, the 2006 guidelines should be modified for a Taiwan population by considering gender.

The Data Gap in the EHR for Clinical Research Eligibility Screening.

Science.gov (United States)

Butler, Alex; Wei, Wei; Yuan, Chi; Kang, Tian; Si, Yuqi; Weng, Chunhua

2018-01-01

Much effort has been devoted to leverage EHR data for matching patients into clinical trials. However, EHRs may not contain all important data elements for clinical research eligibility screening. To better design research-friendly EHRs, an important step is to identify data elements frequently used for eligibility screening but not yet available in EHRs. This study fills this knowledge gap. Using the Alzheimer's disease domain as an example, we performed text mining on the eligibility criteria text in Clinicaltrials.gov to identify frequently used eligibility criteria concepts. We compared them to the EHR data elements of a cohort of Alzheimer's Disease patients to assess the data gap by usingthe OMOP Common Data Model to standardize the representations for both criteria concepts and EHR data elements. We identified the most common SNOMED CT concepts used in Alzheimer 's Disease trials, andfound 40% of common eligibility criteria concepts were not even defined in the concept space in the EHR dataset for a cohort of Alzheimer 'sDisease patients, indicating a significant data gap may impede EHR-based eligibility screening. The results of this study can be useful for designing targeted research data collection forms to help fill the data gap in the EHR.

Chemical compatibility screening test results

International Nuclear Information System (INIS)

Nigrey, P.J.; Dickens, T.G.

1997-12-01

A program for evaluating packaging components that may be used in transporting mixed-waste forms has been developed and the first phase has been completed. This effort involved the screening of ten plastic materials in four simulant mixed-waste types. These plastics were butadiene-acrylonitrile copolymer rubber, cross-linked polyethylene (XLPE), epichlorohydrin rubber, ethylene-propylene rubber (EPDM), fluorocarbon (Viton or Kel-F), polytetrafluoroethylene, high-density polyethylene (HDPE), isobutylene-isoprene copolymer rubber (butyl), polypropylene, and styrene-butadiene rubber (SBR). The selected simulant mixed wastes were (1) an aqueous alkaline mixture of sodium nitrate and sodium nitrite; (2) a chlorinated hydrocarbon mixture; (3) a simulant liquid scintillation fluid; and (4) a mixture of ketones. The testing protocol involved exposing the respective materials to 286,000 rads of gamma radiation followed by 14-day exposures to the waste types at 60 degrees C. The seal materials were tested using vapor transport rate (VTR) measurements while the liner materials were tested using specific gravity as a metric. For these tests, a screening criterion of 0.9 g/hr/m 2 for VTR and a specific gravity change of 10% was used. Based on this work, it was concluded that while all seal materials passed exposure to the aqueous simulant mixed waste, EPDM and SBR had the lowest VTRs. In the chlorinated hydrocarbon simulant mixed waste, only Viton passed the screening tests. In both the simulant scintillation fluid mixed waste and the ketone mixture simulant mixed waste, none of the seal materials met the screening criteria. For specific gravity testing of liner materials, the data showed that while all materials with the exception of polypropylene passed the screening criteria, Kel-F, HDPE, and XLPE offered the greatest resistance to the combination of radiation and chemicals

Screening for retinopathy of prematurity in China: a neonatal units-based prospective study.

Science.gov (United States)

Xu, Yu; Zhou, Xiaohong; Zhang, Qi; Ji, Xunda; Zhang, Qin; Zhu, Jianxing; Chen, Chao; Zhao, Peiquan

2013-12-19

To analyze the incidence and severity of retinopathy of prematurity (ROP) in China, and to explore the workload implications of applying different criteria. A prospective, neonatal units-based study undertaken in two tertiary level hospitals in Shanghai, China, from January 1, 2010 to December 31, 2012. All infants with birth weight (BW) of 2000 g or less and/or gestational age (GA) of 34 weeks or less were screened for ROP. Retinopathy of prematurity was classified using the international classification, and was treated in accordance with the recommendations of the Early Treatment for Retinopathy of Prematurity Cooperative Group. A total of 2825 (93.7%) of 3014 eligible infants were screened, and ROP was diagnosed in 503 infants (17.8%). One hundred ninety-one infants (6.8%) had type 1 or worse ROP and were treated with laser or vitrectomy. The mean GA of ROP patients was 29.9 ± 2.1 weeks and their mean BW was 1425 ± 266 g. Infants who needed treatment for ROP had a mean GA of 29.3 ± 2.1 weeks and mean BW of 1331 ± 330 g. Among these treated infants, 18 infants (9.4%) exceeded the United Kingdom's (UK) screening criteria, and 28 (14.7%) exceeded the criteria used in the United States (US). If narrower criteria, as in GA less than or equal to 33 weeks and/or BW less than or equal to 1750 g were adopted, almost 16.9% fewer infants would not have been examined, with no infant missing treatment. Larger, older infants are at risk in China and screening criteria used in the US and UK may not be suitable for China. Further population-based studies are recommended to determine the necessity of modifying the current ROP screening protocol.

Acceptance criteria considerations for miscellaneous wastes

International Nuclear Information System (INIS)

Irvine, A.R.; Forsberg, C.W.

1987-01-01

EPA standards set forth limitations regarding releases to the accessible environment adjacent to a geologic repository. The NRC criteria pertaining to waste form and engineered barrier performance place certain restrictions on the physical and chemical nature of the waste form and require substantially complete confinement of radioactivity until the high-heat-production period is past. After this period, the annual release of radionuclides from the waste package is normally limited to 1 part in 100,000 of the amounts calculated to be present at 1000-y decay. The regulation permits deviation from these criteria in exceptional circumstances. One such circumstance might be the absence of a significant perturbation in temperature around the stored waste. The lack of significant heat release will eliminate the hydrologic driving force for dispersal of radionuclides. Exceptional circumstances which potentially could justify a less stringent long-term release criterion are: small quantity of radioactivity, the nature of the radioactive species, and the nature of the geology in which the waste is to be emplaced. Because the MW after a suitable decay period have low heat release rates per unit volume, they apparently could be so emplaced in a repository that there would be no compelling need, according to the reasoning presented in 10 CFR 60, for a 1000-y container. Regarding attainment of the specified long-term release rate criterion, neither the solubility limits for the various waste forms nor the conductance of potential migration barriers are currently adequately characterized. The relatively small total heat generation rate for the MW in combination with the usual low volumetric heat generation rate apparently will allow application of migration barriers in a low temperature environment where barrier performance would be expected to be unchanged with time

Risk assessment by the occupational safety and health at work in the process of geological exploration

Directory of Open Access Journals (Sweden)

Staletović Novica M.

2015-01-01

Full Text Available This paper presents a model of risk assessment in terms of safety and health at work in the process of geological work/ drilling. Optimization model estimates OH & S risk for work place qualified driller, is in line with the provisions of the Mining and Geological exploration, the Law on Safety and Health at Work, the application of the requirements of ISO 31000 and criteria Kinny methods. Model estimates OH & S risks is the basis for the development and implementation of the management system of protection of health and safety at work according to BS OHSAS 18001: 2008 model is applied, checked and verified the approved exploration areas during execution and supervision applied geological exploration (of metals on the territory of the Republic of Serbia.

Screening of prospective sites for geological storage of CO{sub 2} in the Southern Baltic Sea

Energy Technology Data Exchange (ETDEWEB)

Vernon, R.; O' Neil, N.; Pasquali, R. [SLR Consulting, Dublin (Ireland); Nieminen, M.

2013-05-15

The BASTOR project focuses on identifying and characterising potential sites for CO{sub 2} storage in the southern Baltic Sea region. A compilation of available digital data from well logs, seismic line data interpretations, mapped structure outlines and published material from existing hydrocarbon fields and identified and mapped structures from Sweden, Poland, Latvia, Lithuania and Kaliningrad have been incorporated into a regional GIS for the Baltic Sea region. A detailed screening of regional sedimentary basins identified the Slupsk Border Zone as having suitable structures for storage of CO{sub 2} in depleted oil and gas fields or saline aquifers. Cambrian sandstone saline aquifers below 900 m have been identified as the principal regional potential storage target with the Dalders Monocline as the most promising area. Eight individual structures were identified as having greatest potential. Detailed 3D geological static models were developed for three of these structures located in offshore Latvia (E6 and E7) and one cross-border structure (Dalders Structure). A theoretical regional CO{sub 2} storage capacity calculation based on the GeoCapacity methodology was undertaken. A regional storage capacity for Cambrian sandstones below 900 m was estimated at a total of 16 Gt, with 2 Gt for the Dalders Monocline. Theoretical storage estimates for individual structures for the Baltic Sea regions includes 760 Mt for the Latvian structures and the Dalders Structure, 9.1 Mt for the structures located in Poland, 31 Mt in Lithuania and 170 Mt in Kaliningrad. These estimates are based on the best available data at the time of writing. However these estimates will be improved upon as new data becomes available from other sources. (orig.)

Reportable Nuclide Criteria for ORNL Radioactive Waste Management Activities - 13005

International Nuclear Information System (INIS)

McDowell, Kip; Forrester, Tim; Saunders, Mark

2013-01-01

The U.S. Department of Energy's Oak Ridge National Laboratory (ORNL) in Oak Ridge, Tennessee generates numerous radioactive waste streams. Many of those streams contain a large number of radionuclides with an extremely broad range of concentrations. To feasibly manage the radionuclide information, ORNL developed reportable nuclide criteria to distinguish between those nuclides in a waste stream that require waste tracking versus those nuclides of such minimal activity that do not require tracking. The criteria include tracking thresholds drawn from ORNL onsite management requirements, transportation requirements, and relevant treatment and disposal facility acceptance criteria. As a management practice, ORNL maintains waste tracking on a nuclide in a specific waste stream if it exceeds any of the reportable nuclide criteria. Nuclides in a specific waste stream that screen out as non-reportable under all these criteria may be dropped from ORNL waste tracking. The benefit of these criteria is to ensure that nuclides in a waste stream with activities which meaningfully affect safety and compliance are tracked, while documenting the basis for removing certain isotopes from further consideration. (authors)

3D representation of geological observations in underground mine workings of the Upper Silesian Coal Basin

Directory of Open Access Journals (Sweden)

Marek Marcisz

Full Text Available The purpose of the paper is to present the possibilities of the three-dimensional representation of geological strata in underground (access workings in a hard coal deposit in the SW part of the Upper Silesian Coal Basin, using CAD software and its flagship program AutoCAD. The 3D visualization of the results of underground workings’ mapping is presented and illustrated on two opening out workings (descending galleries. The criteria for choosing these workings were based on their length and the complexity of geological settings observed while they were driven. The described method may be applied in spatial visualization of geological structures observed in other deposits, mines and existing workings (it is not applicable for designing mine workings, also beyond the area of the Upper Silesian Coal Basin (USCB. The method presented describes the problem of the visualization of underground mine workings in a typical geological aspect, considering (aimed at detailed visualization of geological settings revealed on the side walls of workings cutting the deposit. Keywords: Upper silesian coal basin, Hard coal, Underground mine workings, 3D visualization, CAD

Geological and hydrological exploration of Gulf Coast Salt Domes

International Nuclear Information System (INIS)

Laughon, R.B.

1979-01-01

The geologic exploration program in the Gulf Coast Salt Dome Region is based on a screening process that includes a series of increasingly detailed studies. The screening procedure takes the following steps: (1) determination of regions for further study (in this case, the salt domes of the interior Gulf Coast); (2) regional surveys and the determination of areas within those regions which are thought to be most suitable and which are recommended for further evaluation (in this case, eight specific salt domes); (3) area characterizations and the determination of locations within the areas which are thought to have a high probability of suitability (in this case, two or three of the eight salt domes); (4) location studies and the determination of a potential repository site, which is thought to be suitable and licensable and which is recommended for completion of site characterization studies

China's deep geological disposal program for high level radioactive waste, background and status 1998

International Nuclear Information System (INIS)

Ju Wang; Xu Guoqing; Guo Yonghai

2001-01-01

This paper presents the background and progress made in the study of China's high level radioactive waste, including site screening, site evaluation, the study on radionuclide migration, bentonite, natural analogue studies, and performance assessment, etc. The study on Beishan area, the potential area for China's geological repository, is also presented in this paper. (author)

Screening of electrocatalytic materials for hydrogen evolution

DEFF Research Database (Denmark)

Björketun, Mårten; Bondarenko, Alexander S.; Abrams, Billie

2010-01-01

A general scheme for high-throughput screening of electrocatalysts is presented. By systematically exploiting a collection of theoretical and experimental materials databases, supplemented with quantum mechanical calculations, it locates systems that meet a set of pre-imposed selection criteria...

Geological characterisation of potential disposal areas for radioactive waste from Risoe, Denmark

International Nuclear Information System (INIS)

Gravesen, P.; Binderup, M.; Nilsson, B.; Schack Pedersen, S.A.

2011-01-01

Low- and intermediate-level radioactive waste from the Danish nuclear research facility, Risoe, includes construction materials from the reactors, different types of contaminated material from the research projects and radioactive waste from hospitals, industry and research institutes. This material must be stored in a permanent disposal site in Denmark for at least 300 years. The latter study was conducted by the Geological Survey of Denmark and Greenland (GEUS) and the aim was to locate a sediment or rock body with low permeability down to 100-300 m below the ground surface. GEUS was given the task to locate approximately 20 potential disposal areas. The survey resulted in the selection of 22 areas throughout Denmark. Six of these areas are preferred on geological and hydrogeological criteria. (LN)

The geological characteristics and forming conditions of granite type uranium-rich ore deposits

Energy Technology Data Exchange (ETDEWEB)

Tiangang, Li; Hangshou, Tong; Mingyue, Feng; Yuexiang, Li; Zhan, Xu [Beijing Research Inst. of Uranium Geology (China)

1993-03-01

The forming conditions and concentration mechanism of rich ore, criteria of ore prospecting and selection of uranium-rich ore target area are introduced in the article that is based on the studying of geological characteristics and conditions of granite type uranium-rich ore deposits of No 201 and 361 and on the comparisons of rich and poor ore deposits in geological conditions. Some new view points are also presented as the separate deposition of uranium minerals and gangue minerals is the main mechanism to form rich ore, for rich ore formation the ore enrichment by superimposition is not a universal regularity and most uranium-rich ore deposits are formed within one mineralization stage or mainly in one mineralization stage.

The geological characteristics and forming conditions of granite type uranium-rich ore deposits

International Nuclear Information System (INIS)

Li Tiangang; Tong Hangshou; Feng Mingyue; Li Yuexiang; Xu Zhan

1993-03-01

The forming conditions and concentration mechanism of rich ore, criteria of ore prospecting and selection of uranium-rich ore target area are introduced in the article that is based on the studying of geological characteristics and conditions of granite type uranium-rich ore deposits of No 201 and 361 and on the comparisons of rich and poor ore deposits in geological conditions. Some new view points are also presented as the separate deposition of uranium minerals and gangue minerals is the main mechanism to form rich ore, for rich ore formation the ore enrichment by superimposition is not a universal regularity and most uranium-rich ore deposits are formed within one mineralization stage or mainly in one mineralization stage

Validity of Alcohol Use Disorder Identification Test-Korean Revised Version for Screening Alcohol Use Disorder according to Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition Criteria.

Science.gov (United States)

Chang, Jung Wei; Kim, Jong Sung; Jung, Jin Gyu; Kim, Sung Soo; Yoon, Seok Joon; Jang, Hak Sun

2016-11-01

The Alcohol Use Disorder Identification Test (AUDIT) has been widely used to identify alcohol use disorder (AUD). This study evaluated the validity of the AUDIT-Korean revised version (AUDIT-KR) for screening AUD according to Diagnostic and Statistical Manual of Mental Disorders, fifth edition (DSM-5) criteria. This research was conducted with 443 subjects who visited the Chungnam National University Hospital for a comprehensive medical examination. All subjects completed the demographic questionnaire and AUDIT-KR without assistance. Subjects were divided into two groups according to DSM-5 criteria: an AUD group, which included patients that fit the criteria for AUD (120 males and 21 females), and a non-AUD group, which included 146 males and 156 females that did not meet AUD criteria. The appropriate cut-off values, sensitivity, specificity, and positive and negative predictive values of the AUDIT-KR were evaluated. The mean±standard deviation AUDIT-KR scores were 10.32±7.48 points in males and 3.23±4.42 points in females. The area under the receiver operating characteristic curve (95% confidence interval, CI) of the AUDIT-KR for identifying AUD was 0.884 (0.840-0.920) in males and 0.962 (0.923-0.985) in females. The optimal cut-off value of the AUDIT-KR was 10 points for males (sensitivity, 81.90%; specificity, 81.33%; positive predictive value, 77.2%; negative predictive value, 85.3%) and 5 points for females (sensitivity, 100.00%; specificity, 88.54%; positive predictive value, 52.6%; negative predictive value, 100.0%). The AUDIT-KR has high reliability and validity for identifying AUD according to DSM-5 criteria.

The geological attitude

International Nuclear Information System (INIS)

Fuller, J.G.C.M.

1992-01-01

This paper discusses geological activity which takes place mainly in response to industrial and social pressures. Past geological reaction to these pressures profoundly altered popular conceptions of time, the Church, man, and the balance of nature. The present-day circumstances of geology are not essentially different from those of the past. Petroleum geology in North American illustrates the role of technology in determining the style and scope of geological work. Peaks of activity cluster obviously on the introduction from time to time of new instrumental capabilities (geophysical apparatus, for example), although not infrequently such activity is testing concepts or relationships perceived long before. Organic metamorphism and continental drift provide two examples. The petroleum industry now faces the dilemma of satisfying predicted demands for fuel, without doing irreparable injury to its environment of operation. Awareness of man's place in nature, which is a fundamental perception of geology, governs the geological attitude

Human intruder dose assessment for deep geological disposal

International Nuclear Information System (INIS)

Smith, G. M.; Molinero, J.; Delos, A.; Valls, A.; Conesa, A.; Smith, K.; Hjerpe, T.

2013-07-01

For near-surface disposal, approaches to assessment of inadvertent human intrusion have been developed through international cooperation within the IAEA's ISAM programme. Other assessments have considered intrusion into deep geological disposal facilities, but comparable international cooperation to develop an approach for deep disposal has not taken place. Accordingly, the BIOPROTA collaboration project presented here (1) examined the technical aspects of why and how deep geological intrusion might occur; (2) considered how and to what degree radiation exposure would arise to the people involved in such intrusion; (3) identified the processes which constrain the uncertainties; and hence (4) developed and documented an approach for evaluation of human intruder doses which addresses the criteria adopted by the IAEA and takes account of other international guidance and human intrusion assessment experience. Models for radiation exposure of the drilling workers and geologists were developed and described together with compilation of relevant input data, taking into account relevant combinations of drilling technique, geological formation and repository material. Consideration has been given also to others who might be exposed to contaminated material left at the site after drilling work has ceased. The models have been designed to be simple and stylised, in accordance with international recommendations. The set of combinations comprises 58 different scenarios which cover a very wide range of human intrusion possibilities via deep drilling. (orig.)

Quantitative geological modeling based on probabilistic integration of geological and geophysical data

DEFF Research Database (Denmark)

Gulbrandsen, Mats Lundh

In order to obtain an adequate geological model of any kind, proper integration of geophysical data, borehole logs and geological expert knowledge is important. Geophysical data provide indirect information about geology, borehole logs provide sparse point wise direct information about geology...... entitled Smart Interpretation is developed. This semi-automatic method learns the relation between a set of data attributes extracted from deterministically inverted airborne electromagnetic data and a set of interpretations of a geological layer that is manually picked by a geological expert...

Refining Lung Cancer Screening Criteria in the Era of Value-Based Medicine.

Directory of Open Access Journals (Sweden)

Steven D Shapiro

2017-02-01

Full Text Available In a Perspective on the Research Article by ten Haaf and colleagues, Steven Shapiro discusses the challenges of identifying screening strategies that maximize the number of cancers diagnosed, while minimizing the harms of overdiagnosis and maintaining cost-effectiveness.

Evolving interpretation of the athlete's electrocardiogram: from European Society of Cardiology and Stanford criteria, to Seattle criteria and beyond.

Science.gov (United States)

Zorzi, Alessandro; ElMaghawry, Mohamed; Corrado, Domenico

2015-01-01

Electrocardiographic (ECG) pre-participation screening can prevent sudden cardiac death in the athletes by early diagnosis and disqualification of affected individuals. Interpretation of the athlete's ECG should be based on specific criteria, because ECG changes that would be considered abnormal in the untrained population may develop in trained athletes as a physiologic and benign consequence of the heart's adaptation to exercise. In 2010, a stem document from the Section of Sports Cardiology of the European Society of Cardiology (ESC) proposed to classify the athlete's ECG changes according to the prevalence, relation to exercise training, association with an increased risk of cardiovascular disease and need for further investigations into two groups: "common and training-related" (Group 1) and "uncommon and training-unrelated" (Group 2). Over the last years, several efforts have been made to refine the ESC criteria for interpretation of the athlete's ECG in order to improve specificity maintaining good sensitivity, especially among elite and Afro-Caribbean athletes, which show the highest rate of false positives Group 2 ECG abnormalities. However, the balance between improvement in specificity and loss of sensitivity should be evaluated keeping in mind that the primary aim of the screening program is to save the athlete's lives rather than money. Copyright © 2015 Elsevier Inc. All rights reserved.

Seismic design criteria for the Clinch River Breeder Reactor Plant

International Nuclear Information System (INIS)

Morrone, A.; Bitner, J.L.; Sigal, G.B.

1975-01-01

The general criteria for seismic resistant design for structures, systems and components of the Clinch River Breeder Reactor Plant (CRBRP) are presented and discussed. Site dependency of the maximum ground accelerations for the Operating Basis Earthquake and the Safe Shutdown Earthquake is described from the viewpoint of historical records and geological and seismological studies for the CRBRP site. The respective ground response spectra are derived by normalization of the latest AEC Regulatory standard shapes to these maximum ground accelerations. Modeling and analytical techniques and requirements are given. In addition, loading conditions and categories, loading combinations, earthquake direction effects and allowable damping values are defined. A discussion of the testing criteria which considers both single and multiple frequency test motions, and basic test procedures for single frequency sine beat testing is presented. (U.S.)

Design Criteria for Process Wastewater Pretreatment Facilities

Science.gov (United States)

1988-05-01

Stripping Column H13 ’Re Purpose: The purpose of this report, is to provide design criteria for pretreatment needs for ’ I. INTRODUCTION ’". discharge of...which a portion of the vessel is filled with packing. Packing materials vary from corrugated steel to bundles of fibers (Langdon et al., 1972) to beds...concentration(s) using Table 20. Wastewater treatability studies should be considered as a process-screening tool for all wastewater streams for

Geological criteria for site selection of an LILW radioactive waste repository in the Philippines

International Nuclear Information System (INIS)

Aurelio, Mario; Taguibao, Kristine Joy; Vargas, Edmundo; Palattao, Maria Visitacion; Reyes, Rolando; Nohay, Carl; Singayan, Alfonso

2013-01-01

In the selection of sites for disposal facilities involving low- and intermediate-level radioactive waste (LILW), International Atomic Energy Agency (IAEA) recommendations require that 'the region in which the site is located shall be such that significant tectonic and surface processes are not expected to occur with an intensity that would compromise the required isolation capability of the repository'. Evaluating the appropriateness of a site therefore requires a deep understanding of the geological and tectonic setting of the area. The Philippines sits in a tectonically active region frequented by earthquakes and volcanic activity. Its highly variable morphology coupled with its location along the typhoon corridor in the west Pacific region subjects the country to surface processes often manifested in the form of landslides. The Philippine LILW near surface repository project site is located on the north eastern sector of the Island of Luzon in northern Philippines. This island is surrounded by active subduction trenches; to the east by the East Luzon Trough and to the west by the Manila Trench. The island is also traversed by several branches of the Philippine Fault System. The Philippine LILW repository project is located more than 100 km away from any of these major active fault systems. In the near field, the project site is located less than 10 km from a minor fault (Dummon River Fault) and more than 40 km away from a volcanic edifice (Mt. Caguas). This paper presents an analysis of the potential hazards that these active tectonic features may pose to the project site. The assessment of such geologic hazards is imperative in the characterization of the site and a crucial input in the design and safety assessment of the repository. (authors)

Geological criteria for site selection of an LILW radioactive waste repository in the Philippines

Energy Technology Data Exchange (ETDEWEB)

Aurelio, Mario; Taguibao, Kristine Joy [National Institute of Geological Sciences, University of the Philippines, Quezon City (Philippines); Vargas, Edmundo; Palattao, Maria Visitacion; Reyes, Rolando; Nohay, Carl; Singayan, Alfonso [Philippine Nuclear Research Institute, Department of Science and Technology, Quezon City (Philippines)

2013-07-01

In the selection of sites for disposal facilities involving low- and intermediate-level radioactive waste (LILW), International Atomic Energy Agency (IAEA) recommendations require that 'the region in which the site is located shall be such that significant tectonic and surface processes are not expected to occur with an intensity that would compromise the required isolation capability of the repository'. Evaluating the appropriateness of a site therefore requires a deep understanding of the geological and tectonic setting of the area. The Philippines sits in a tectonically active region frequented by earthquakes and volcanic activity. Its highly variable morphology coupled with its location along the typhoon corridor in the west Pacific region subjects the country to surface processes often manifested in the form of landslides. The Philippine LILW near surface repository project site is located on the north eastern sector of the Island of Luzon in northern Philippines. This island is surrounded by active subduction trenches; to the east by the East Luzon Trough and to the west by the Manila Trench. The island is also traversed by several branches of the Philippine Fault System. The Philippine LILW repository project is located more than 100 km away from any of these major active fault systems. In the near field, the project site is located less than 10 km from a minor fault (Dummon River Fault) and more than 40 km away from a volcanic edifice (Mt. Caguas). This paper presents an analysis of the potential hazards that these active tectonic features may pose to the project site. The assessment of such geologic hazards is imperative in the characterization of the site and a crucial input in the design and safety assessment of the repository. (authors)

Terrestrial analogs, planetary geology, and the nature of geological reasoning

Science.gov (United States)

Baker, Victor R.

2014-05-01

Analogical reasoning is critical to planetary geology, but its role can be misconstrued by those unfamiliar with the practice of that science. The methodological importance of analogy to geology lies in the formulation of genetic hypotheses, an absolutely essential component of geological reasoning that was either ignored or denigrated by most 20th century philosophers of science, who took the theoretical/ experimental methodology of physics to be the sole model for all of scientific inquiry. Following the seminal 19th century work of Grove Karl Gilbert, an early pioneer of planetary geology, it has long been recognized that broad experience with and understanding of terrestrial geological phenomena provide geologists with their most effective resource for the invention of potentially fruitful, working hypotheses. The actions of (1) forming such hypotheses, (2) following their consequences, and (3) testing those consequences comprise integral parts of effective geological practice in regard to the understanding of planetary surfaces. Nevertheless, the logical terminology and philosophical bases for such practice will be unfamiliar to most planetary scientists, both geologists and nongeologists. The invention of geological hypotheses involves both inductive inferences of the type Gilbert termed “empiric classification” and abductive inferences of a logical form made famous by the 19th century American logician Charles Sanders Peirce. The testing and corroboration of geological hypotheses relies less on the correspondence logic of theoretical/ experimental sciences, like physics, and more on the logic of consistency, coherence, and consilience that characterizes the investigative and historical sciences of interpretation exemplified by geology.

Health benefits of geologic materials and geologic processes

Science.gov (United States)

Finkelman, R.B.

2006-01-01

The reemerging field of Medical Geology is concerned with the impacts of geologic materials and geologic processes on animal and human health. Most medical geology research has been focused on health problems caused by excess or deficiency of trace elements, exposure to ambient dust, and on other geologically related health problems or health problems for which geoscience tools, techniques, or databases could be applied. Little, if any, attention has been focused on the beneficial health effects of rocks, minerals, and geologic processes. These beneficial effects may have been recognized as long as two million years ago and include emotional, mental, and physical health benefits. Some of the earliest known medicines were derived from rocks and minerals. For thousands of years various clays have been used as an antidote for poisons. "Terra sigillata," still in use today, may have been the first patented medicine. Many trace elements, rocks, and minerals are used today in a wide variety of pharmaceuticals and health care products. There is also a segment of society that believes in the curative and preventative properties of crystals (talismans and amulets). Metals and trace elements are being used in some of today's most sophisticated medical applications. Other recent examples of beneficial effects of geologic materials and processes include epidemiological studies in Japan that have identified a wide range of health problems (such as muscle and joint pain, hemorrhoids, burns, gout, etc.) that may be treated by one or more of nine chemically distinct types of hot springs, and a study in China indicating that residential coal combustion may be mobilizing sufficient iodine to prevent iodine deficiency disease. ?? 2006 MDPI. All rights reserved.

Identifying Glucokinase Monogenic Diabetes in a Multiethnic Gestational Diabetes Mellitus Cohort: New Pregnancy Screening Criteria and Utility of HbA1c.

Science.gov (United States)

Rudland, Victoria L; Hinchcliffe, Marcus; Pinner, Jason; Cole, Stuart; Mercorella, Belinda; Molyneaux, Lynda; Constantino, Maria; Yue, Dennis K; Ross, Glynis P; Wong, Jencia

2016-01-01

Glucokinase monogenic diabetes (GCK-maturity-onset diabetes of the young [MODY]) should be differentiated from gestational diabetes mellitus (GDM) because management differs. New pregnancy-specific screening criteria (NSC) have been proposed to identify women who warrant GCK genetic testing. We tested NSC and HbA1c in a multiethnic GDM cohort and examined projected referrals for GCK testing. Using a GDM database, 63 of 776 women had a postpartum oral glucose tolerance test suggestive of GCK-MODY. Of these 63 women, 31 agreed to undergo GCK testing. NSC accuracy and HbA1c were examined. Projected referrals were calculated by applying the NSC to a larger GDM database (n = 4,415). Four of 31 women were confirmed as having GCK-MODY (prevalence ∼0.5-1/100 with GDM). The NSC identified all Anglo-Celtic women but did not identify one Indian woman. The NSC will refer 6.1% of GDM cases for GCK testing, with more Asian/Indian women referred despite lower disease prevalence. Antepartum HbA1c was not higher in those with GCK-MODY. The NSC performed well in Anglo-Celtic women. Ethnic-specific criteria should be explored. © 2016 by the American Diabetes Association. Readers may use this article as long as the work is properly cited, the use is educational and not for profit, and the work is not altered.

Potentially inappropriate medications in elderly Japanese patients: effects of pharmacists' assessment and intervention based on Screening Tool of Older Persons' Potentially Inappropriate Prescriptions criteria ver.2.

Science.gov (United States)

Kimura, T; Ogura, F; Yamamoto, K; Uda, A; Nishioka, T; Kume, M; Makimoto, H; Yano, I; Hirai, M

2017-04-01

The Screening Tool of Older Persons' Potentially Inappropriate Prescriptions (stopp) criteria were updated in 2014 (stopp criteria ver.2), but few studies have evaluated the usefulness of stopp criteria in elderly patients. This prospective observational study evaluated the prevalence of potentially inappropriate medications (PIMs), and the efficacy of hospital pharmacists' assessment and intervention based on stopp criteria ver.2. The study was conducted at three medical units of Kobe University Hospital between April 2015 and March 2016. Pharmacists assessed and detected PIMs based on stopp criteria ver.2 and considered the patient's intention to change the prescription at the time of admission of each patient. If the pharmacists judged that benefits outweighed risks of prescription change and the patients consented to change the medications, they recommended the doctor to change the prescription. If there was a risk of exacerbation of disease by the change of medications and the pharmacists judged it to be difficult to adjust medications during hospitalization or the patients did not consent to change the medications, they did not recommend to change it. The pharmacists and the doctors discussed and finally decided whether to change the PIMs or not. The number of patients prescribed PIMs, the number and contents of PIMs, and the number of medications changed after pharmacists' intervention were calculated. Totally, 822 new inpatients aged ≥65 years prescribed ≥1 daily medicine were included. Their median (interquartile range) age was 75·0 (71·0-80·0) years, and 54·9% were male. According to the criteria, 346 patients (42·1%) were prescribed ≥1 PIMs. Patients prescribed PIMs took significantly more medications than others: 10·0 (7·0-13·0) vs. 6·0 (4·0-9·0), P older people (benzodiazepines) (30/67) and (iii) drugs that predictably increase the risk of falls in older people (hypnotic Z-drugs) (15/31). Over 40% elderly patients were prescribed PIMs

Site characterization criteria (DOE-STD-1022-94) for natural phenomena hazards at DOE sites. Revision 1

International Nuclear Information System (INIS)

Chen, J.C.; Ueng, Tzou-Shin; Boissonnade, A.C.

1995-01-01

This paper briefly summarizes requirements of site characterization for Natural Phenomena Hazards (NPH) at DOE sites. In order to comply with DOE Order 5480.28, site characterization criteria has been developed to provide site-specific information needed for development of NPH assessment criteria. Appropriate approaches are outlined to ensure that the current state-of-the-art methodologies and procedures are used in the site characterization. General and detailed site characterization requirements are provided in the areas of meteorology, hydrology, geology, seismology and geotechnical studies

Assessment of effectiveness of geologic isolation systems: a short description of the AEGIS approach

International Nuclear Information System (INIS)

Silviera, D.J.; Harwell, M.A.; Napier, B.A.; Zellmer, J.T.; Benson, G.L.

1980-09-01

To meet licensing criteria and protection standards for HLW disposal, research programs are in progress to determine acceptable waste forms, canisters, backfill materials for the repository, and geological formations. Methods must be developed to evaluate the effectiveness of the total system. To meet this need, methods are being developed to assess the long-term effectiveness of isolating nuclear wastes in geologic formations. This work was started in 1976 in the Waste Isolation Safety Assessment Program (WISAP) and continues in the Assessment of Effectiveness of Geologic Isolation Systems (AEGIS) Program. The evaluation of this long-term effectiveness involves a number of distinct steps. AEGIS currently has the methods for performing these evaluation steps. These methods are continuously being improved to meet the inreasing level of sophistication which will be required. AEGIS develops a conceptual description of the geologic systems and uses computer models to simulate the existing ground-water pathways. AEGIS also uses a team of consulting experts, with the assistance of a computer model of the geologic processes, to develop and evaluate plausible release scenarios. Then other AEGIS computer models are used to simulate the transport of radionuclides to the surface and the resultant radiation doses to individuals and populations

Development of wall thinning screening system and its application to a commercial nuclear power plant

International Nuclear Information System (INIS)

Ryu, Kyung Ha; Hwang, Il Soon; Kim, Ji Hyun

2013-01-01

Highlights: • Wall loss screening system (WalSS) has been developed based on ES-DCPD method. • Screening criteria was established based on the thinning of the actual shape that occur in the power plant. • With the criteria, the WalSS gives priority of the need for inspection. • This technique was successfully applied to commercial nuclear power plant. - Abstract: A new non-destructive evaluation (NDE) method has been developed for metal pipes for the detection wall thinning. The method has been showed to be suitable for applications to electric power generation plants where flow accelerated corrosion (FAC) of carbon steel piping is a significant cause of increased maintenance and plant personnel casualty. The wall thinning screening system (WalSS) was developed in two major phases. In the first phase, the equipotential switching direct current potential drop (ES-DCPD) method was developed for piping wall (Ryu et al., 2008a, 2010). In the second phase, in this paper, a quantitative detection criteria was developed. The relative ES-DCPD change of 3.8% has been defined as the screening criteria for wall thinning schematization. This criteria means that the component with measured ES-DCPD change greater than 3.8% is called for a more comprehensive examination. In the criteria development, all variables were taken into consideration based on commercial plant piping inspection data such as initial thickness distributions, wall thinning shape and nominal thickness. The developed WalSS based on ES-DCPD was applied to a moisture separator reheater (MSR) drain line of a commercial nuclear power plant (NPP) during a scheduled overhaul. The measured ES-DCPD change was 2.16%, which is lower than the ES-DCPD criteria, identifying the pipe having adequate wall thickness. This is confirmed by site thickness inspection using ultrasonic technique (UT)

Genomic screening for dissection of a complex disease: The multiple sclerosis phenotype

Energy Technology Data Exchange (ETDEWEB)

Haines, J.L.; Bazyk, A.; Gusella, J.F. [Massachusetts General Hospital, Boston, MA (United States)] [and others

1994-09-01

Application of positional cloning to diseases with a complex etiology is fraught with problems. These include undefined modes of inheritance, heterogeneity, and epistasis. Although microsatellite markers now make genotyping the genome a straightforward task, no single analytical method is available to efficiently and accurately use these data for a complex disease. We have developed a multi-stage genomic screening strategy which uses a combination of non-parametric approaches (Affected Pedigree Member (APM) linkage analysis and robust sib pair analysis (SP)), and the parametric lod score approach (using four different genetic models). To warrant follow-up, a marker must have two or more of: a nominal P value of 0.05 or less on the non-parametric tests, or a lod score greater than 1.0 for any model. Two adjacent markers each fulfilling one criterion are also considered for follow-up. These criteria were determined both by simulation studies and our empirical experience in screening a large number of other disorders. We applied this approach to multiple sclerosis (MS), a complex neurological disorder with a strong but ill-defined genetic component. Analysis of the first 91 markers from our screen of 55 multiplex families found 5 markers which met the SP criteria, 13 markers which met the APM criteria, and 8 markers which met the lod score criteria. Five regions (on chromosomes 2, 4, 7, 14, and 19) met our overall criteria. However, no single method identified all of these regions, suggesting that each method is sensitive to various (unknown) influences. The chromosome 14 results were not supported by follow-up typing and analysis of markers in that region, but the chromosome 19 results remain well supported. Updated screening results will be presented.

Discussion of quantitative assessment index system of suitability of the site for geological disposal repository of high-level radioactive waste

International Nuclear Information System (INIS)

Su Rui; Wang Ju

2014-01-01

Site selection and suitability assessment of site are one of important tasks of research and development of geological disposal engineering for high-level radioactive waste (HLW). Quantitative assessment of suitability of the site is based on the scientific, reasonable and operational index system. The discussion of index screening of quantitative assessment of suitability of the site is conducted. Principle of index screening is presented and index systems are established for different stages of site selection, including planning stage of site selection, region or area investigation stage, site characterization and site confirmation stage. But the considerations are taken of the complexity of site selection of geological disposal engineering for HLW and itself development of quantitative assessment method, so improvement of the index systems presented above is needed in the further. (authors)

Multi-data integration of exploration criteria and selection of prospecting targets

International Nuclear Information System (INIS)

Dechang, L.; Jingke, Z.; Maorong, S.; Guojuan, W.

1991-01-01

In this paper based on the analysis of the exploration criteria for Shengyuan Basin-a uranium ore field, the multi-data integration and information extraction of exploration criteria are carried out on computer and image processing system so that the areas with best combinations of exploration criteria are directly displayed on the screen. Six prospecting targets are selected through the field examination. Shengyuan basin in Jiangxi province is a uranium-producing, Jurassic Cretaceous volcanic-sedimentary basin with an area of about 400 sq km. Its basement consists of Sinian-Cambrian rocks with Caledonian granites intruded. Several uranium deposits, occurrences and anomalies were discovered over the basin region which, therefore, becomes a very important uranium ore field in China

Newborn Screening for Phenylketonuria

Directory of Open Access Journals (Sweden)

Gustavo J. C. Borrajo PhD

2016-12-01

Full Text Available Newborn screening (NBS for phenylketonuria in Latin America gave its first step in an organized way 3 decades ago when the first national NBS program was implemented in Cuba. From then onward, it experienced a slow but continuous growing, being currently possible to find from countries where no NBS activity is known to several countries with consolidated NBS programs. This complex scenario gave rise to a great diversity in the criteria used for sample collection, selection of analytical methods, and definition of cutoff values. Considering this context, a consensus meeting was held in order to unify such criteria, focusing the discussion in the following aspects—recommended blood specimens and sample collection time; influence of early discharge, fasting, parenteral nutrition, blood transfusions, extracorporeal life support, and antibiotics; main causes of transient hyperphenylalaninemias; required characteristics for methods used in phenylalanine measurement; and finally, criteria to define the more appropriate cutoff values.

Chemical compatibility screening results of plastic packaging to mixed waste simulants

International Nuclear Information System (INIS)

Nigrey, P.J.; Dickens, T.G.

1995-01-01

We have developed a chemical compatibility program for evaluating transportation packaging components for transporting mixed waste forms. We have performed the first phase of this experimental program to determine the effects of simulant mixed wastes on packaging materials. This effort involved the screening of 10 plastic materials in four liquid mixed waste simulants. The testing protocol involved exposing the respective materials to ∼3 kGy of gamma radiation followed by 14 day exposures to the waste simulants of 60 C. The seal materials or rubbers were tested using VTR (vapor transport rate) measurements while the liner materials were tested using specific gravity as a metric. For these tests, a screening criteria of ∼1 g/m 2 /hr for VTR and a specific gravity change of 10% was used. It was concluded that while all seal materials passed exposure to the aqueous simulant mixed waste, EPDM and SBR had the lowest VTRs. In the chlorinated hydrocarbon simulant mixed waste, only VITON passed the screening tests. In both the simulant scintillation fluid mixed waste and the ketone mixture simulant mixed waste, none of the seal materials met the screening criteria. It is anticipated that those materials with the lowest VTRs will be evaluated in the comprehensive phase of the program. For specific gravity testing of liner materials the data showed that while all materials with the exception of polypropylene passed the screening criteria, Kel-F, HDPE, and XLPE were found to offer the greatest resistance to the combination of radiation and chemicals

Selection of nuclide decay chains for use in the assessment of the radiological impact of geological repositories for radioactive waste

International Nuclear Information System (INIS)

Thorne, M.C.

1982-12-01

The criteria for selecting nuclide decay chains for use in the assessment of the radiological impact of geological repositories for radioactive waste are given. The reduced chains recommended for use with SYVAC are described. (author)

Criteria for high-level waste disposal

International Nuclear Information System (INIS)

Sousselier, Y.

1981-01-01

Disposal of radioactive wastes is storage without the intention of retrieval. But in such storage, it may be useful and in some cases necessary to have the possibility of retrieval at least for a certain period of time. In order to propose some criteria for HLW disposal, one has to examine how this basic concept is to be applied. HLW is waste separated as a raffinate in the first cycle of solvent extraction in reprocessing. Such waste contains the bulk of fission products which have long half lives, therefore the safety of a disposal site, at least after a certain period of time, must be intrinsic, i.e. not based on human intervention. There is a consensus that such a disposal is feasible in a suitable geological formation in which the integrity of the container will be reinforced by several additional barriers. Criteria for disposal can be proposed for all aspects of the question. The author discusses the aims of the safety analysis, particularly the length of time for this analysis, and the acceptable dose commitments resulting from the release of radionuclides, the number and role of each barrier, and a holistic analysis of safety external factors. (Auth.)

Site characterization information needs for a high-level waste geologic repository

International Nuclear Information System (INIS)

Gupta, D.C.; Nataraja, M.S.; Justus, P.S.

1987-01-01

At each of the three candidate sites recommended for site characterization for High-Level Waste Geologic Repository development, the DOE has proposed to conduct both surface-based testing and in situ exploration and testing at the depths that wastes would be emplaced. The basic information needs and consequently the planned surface-based and in situ testing program will be governed to a large extent by the amount of credit taken for individual components of the geologic repository in meeting the performance objectives and siting criteria. Therefore, identified information to be acquired from site characterization activities should be commensurate with DOE's assigned performance goals for the repository system components on a site-specific basis. Because of the uncertainties that are likely to be associated with initial assignment of performance goals, the information needs should be both reasonably and conservatively identified

Considerations for developing seismic design criteria for nuclear waste storage repositories

International Nuclear Information System (INIS)

Owen, G.N.; Yanev, P.I.; Scholl, R.E.

1980-04-01

The function of seismic design criteria is to reduce the potential for hazards that may arise during various stages of the repository life. During the operational phase, the major concern is with the possible effects of earthquakes on surface facilities, underground facilities, and equipment. During the decommissioned phase, the major concern is with the potential effects of earthquakes on the geologic formation, which may result in a reduction in isolation capacity. Existing standards and guides or criteria used for the static and seismic design of licensed nuclear facilities were reviewed and evaluated for their applicability to repository design. This report is directed mainly toward the development of seismic design criteria for the underground structures of repositories. An initial step in the development of seismic design criteria for the underground structures of repositories is the development of performance criteria, or minimum standards of acceptable behavior. A number of possible damage modes are identified for the operating phase of the repository; however, no damage modes are foreseen that would perturb the long-term function of the repository, except for the possibility of increased permeability within the rock mass. Subsequent steps in formulating acceptable seismic design criteria for the underground structures involve the quantification of the design process. The report discusses the necessity of specifying the form of ground motion that would be needed for seismic analysis and the procedures that may be used for making ground motion predictions. Further discussions outline what is needed for analysis, including rock properties, failure criteria, modeling techniques, seismic hardening criteria for the host rock mass, and probabilistic considerations

Criteria and results from the analysis of the problem of site selection for the construction of high level RAW repository

International Nuclear Information System (INIS)

Evstatiev, D.; Kozhoukharova, D.; Iliev, I.; Karagyuleva, J.

1993-02-01

The criteria for preliminary assessment of the Bulgarian territory and the results of the selection of prospective sites for future investigation concerning the choice of the suitable places for RAW repositories are presented. The selection of the prospective terrains has been performed in two stages: 1) Categorization of the country according to the prospective conditions for suitable sites and 2) Distinguishing and preliminary assessment of the suitable sites. The number of these sites was reduced to 20 by the method of successive screening. They are located in Northwest and Southeast Bulgaria and are built of marls, clays, granite, gneiss, serpentine and and volcanic rocks. The selected 20 sites has been subjected to preliminary investigation according to a programme specially worked out for the purpose. The investigation covers the analysis and summing up of the available geographical, geomorphological, geological, seismotectonic, hydrological, climatic, hydrogeological and geotechnical data, as well as a minimum of additional field research and laboratory tests. The results of the investigation of each site are presented and discussed. 1 ref

Geology and bedrock engineering

International Nuclear Information System (INIS)

1985-11-01

This book deals with geology of Korea which includes summary, geology in central part and southern part in Korea and characteristic of geology structure, limestone like geology property of limestone, engineered property of limestone, and design and construction case in limestone area. It also introduces engineered property of the cenozoic, clay rock and shale, geologic and engineered property of phyllite and stratum.

Screening of synfuel processes for HTGR application

International Nuclear Information System (INIS)

1981-02-01

The aim of this study is to select for further study, the several synfuel processes which are the most attractive for application of HTGR heat and energy. In pursuing this objective, the Working Group identified 34 candidate synfuel processes, cut the number of processes to 16 in an initial screening, established 11 prime criteria with weighting factors for use in screening the remaining processes, developed a screening methodology and assumptions, collected process energy requirement information, and performed a comparative rating of the processes. As a result of this, three oil shale retorting processes, two coal liquefaction processes and one coal gasification process were selected as those of most interest for further study at this time

Program criteria for subseabed disposal of radioactive waste: site qualification plan

International Nuclear Information System (INIS)

Laine, E.P.; Anderson, D.R.; Hollister, C.D.

1982-05-01

This document describes the evolving methodology which is being used to identify, and study sites in subseabed geological formations which may be candidates for use as repositories for high-level nuclear waste. Two primary criteria guide all phases of this work: the stability and barrier criteria. The stability criterion defines areas of the seabed that are unlikely to be disturbed by tectonic forces and oceanographic changes durig the lifetime of a waste repository. The barrier criterion defines those subseabed geological formations most likely to form an effective barrier to the release of radionuclides. Because of the large area of the oceans, a phased approach has been adopted through which successively smaller areas of the sea floor are studied in ever greater detail. The first phase, which is complete, has identified abyssal clay deposits that are remote from tectonic boundaries and continental margins as being the regions (>10 5 km 2 ) on the sea floor within which acceptable sites might be most readily identified. The second phase involves downgrading less desirable areas (>10 4 km 2 ) within these regions, using archived seismic reflection profiling, sediment cores, and oceanographic data. This winnowing process identifies locations about one degree square (greater than or equal to 10 4 km 2 ) for more detailed field studies during the first part of the third phase. From these locations candidate sites (less than or equal to 10 4 km 2 ) will be chosen based on detailed geological and geophysical surveying. In the second part of the third phase, detailed monitoring of the candidate sites will begin to determine long-term baseline conditions. After monitoring is underway, a pilot repository will be established using waste canisters. Based on this work, a site selection/rejection report will be written. The fourth and last phase will involve extended monitoring of oceanographic conditions at each repository

Gender differences in the electrocardiogram screening of athletes.

Science.gov (United States)

Bessem, Bram B; de Bruijn, Matthijs M C; Nieuwland, Wybe W

2017-02-01

Gender-related differences are frequently used in medicine. Electrocardiograms are also subject to such differences. This study evaluated gender differences in ECG parameters of young athletes, discussing the possible implications of these differences for ECG criteria used in the cardiovascular screening of young athletes. Observational cross-sectional study. In 2013 and 2014 all the ECGs from the cardiovascular screenings performed at University Sports Medical Centre in Groningen of the student athletes who wanted to participate in a college sports program were collected. The ECG characteristics were scored using computer-based measurements and the Seattle ECG criteria. The study population included 1436 athletes, of which 72% were male. Male athletes were older (19.3 years vs. 18.6 years), participated in sports more frequently (4.0/week vs. 3.8/week) and spent more hours per week practising sports (6.4h/week vs. 5.8h/week) than female athletes. Male athletes had significantly higher PR intervals (149ms vs. 141ms), lead voltages and QRS duration (98ms vs. 88ms). Female athletes had significantly higher resting heart rates (69/min vs. 64/min) and QTc intervals (407ms vs. 400ms). Male athletes also had significantly higher amounts of sinus bradycardia (38.3% vs. 23.0%), incomplete RBBB (15.0% vs. 3.7%), early repolarisation (4.5% vs. 1.0%) and isolated QRS voltage criteria for LVH (26.3% vs. 4.6%). All P-values were ≤0.001. ECGs of young athletes demonstrate gender-related differences. These differences could be considered in their cardiovascular screening. For the Seattle ECG criteria we advise additional research into the clinical implications of using gender-based cut-off values for the QRS duration in the intraventricular conduction delay criterion. Copyright © 2016 Sports Medicine Australia. Published by Elsevier Ltd. All rights reserved.

Study on geology and geological structure based on literature studies

International Nuclear Information System (INIS)

Funaki, Hironori; Ishii, Eiichi; Yasue, Ken-ichi; Takahashi, Kazuharu

2005-03-01

Japan Nuclear Cycle Development Institute (JNC) is proceeding with underground research laboratory (URL) project for the sedimentary rock in Horonobe, Hokkaido. This project is an investigation project which is planned over 20 years. Surface-based investigations (Phase 1) have been conducted for the present. The purposes of the Phase 1 are to construct the geological environment model (geological-structural, hydrogeological, and hydrochemical models) and to confirm the applicability of investigation technologies for the geological environment. The geological-structural model comprises the base for the hydrogeological and hydrochemical models. We constructed the geological-structural model by mainly using data obtained from literature studies. Particulars regarding which data the model is based on and who has performed the interpretation are also saved for traceability. As a result, we explain the understanding of degree and the need of information on stratigraphy and discontinuous structure. (author)

Hydrogeological Properties of Geological Elements in Geological Model around KURT

Energy Technology Data Exchange (ETDEWEB)

Park, Kyung Woo; Kim, Kyung Soo; Koh, Yong Kwon; Choi, Jong Won [Korea Atomic Energy Institue, Daejeon (Korea, Republic of)

2012-09-15

To develop site characterization technologies for a radioactive waste disposal research in KAERI, the geological and hydrogeological investigations have been carried out since 1997. In 2006, the KURT (KAERI Underground Research Tunnel) was constructed to study a solute migration, a microbiology and an engineered barrier system as well as deeply to understand geological environments in in-situ condition. This study is performed as one of the site characterization works around KURT. Several investigations such as a lineament analysis, a borehole/tunnel survey, a geophyscial survey and logging in borehole, were used to construct the geological model. As a result, the geological model is constructed, which includes the lithological model and geo-structural model in this study. Moreover, from the results of the in-situ hydraulic tests, the hydrogeological properties of elements in geological model were evaluated.

Hydrogeological Properties of Geological Elements in Geological Model around KURT

International Nuclear Information System (INIS)

Park, Kyung Woo; Kim, Kyung Soo; Koh, Yong Kwon; Choi, Jong Won

2012-01-01

To develop site characterization technologies for a radioactive waste disposal research in KAERI, the geological and hydrogeological investigations have been carried out since 1997. In 2006, the KURT (KAERI Underground Research Tunnel) was constructed to study a solute migration, a microbiology and an engineered barrier system as well as deeply to understand geological environments in in-situ condition. This study is performed as one of the site characterization works around KURT. Several investigations such as a lineament analysis, a borehole/tunnel survey, a geophyscial survey and logging in borehole, were used to construct the geological model. As a result, the geological model is constructed, which includes the lithological model and geo-structural model in this study. Moreover, from the results of the in-situ hydraulic tests, the hydrogeological properties of elements in geological model were evaluated.

Geological signatures of drillhole radar reflectors in ONKALO

International Nuclear Information System (INIS)

Doese, C.; Gustafsson, J.

2011-12-01

The geological signatures of radar reflectors in ONKALO have been evaluated as a subactivity within the Joint Work Programme 'Rock Suitability Criteria' strategies and methodology' between Svensk Kaernbraenslehantering AB and Posiva Oy. In addition to the geological signature, the usage of geophysical data to predict large fractures was evaluated. Pilot hole radar loggings were carried out using a RAMAC GPR-250 MHz dipole antenna. The radar data were evaluated and reflectors with known position and intersection angle to the pilot hole were correlated with fractures or foliation in the pilot hole and with Tunnel Crosscutting Fractures in the tunnel. This data served as in-data for the evaluation of the geological signatures of radar reflectors. The result of the evaluation is not univocal. Half of the reflectors could be explained by fractures in the pilot hole, but only about 10 % of the reflectors can be explained by Tunnel Crosscutting Fractures. Of these 10 %, 2/3 can also be explained by foliation, leaving only some 3 % of the total reflectors more unambiguously correlated with Tunnel Crosscutting Fractures. The fractures correlated with radar reflectors do not diverge much from other fractures. Fractures having intersection angles of 30 deg- 60 deg are more likely to be detected by radar relative to other. Other properties that seem to be overrepresented in fractures correlated with radar reflectors are quartz and/or graphite content, width ≥0.8 mm and higher alteration (J a ≥3), but the data is not unambiguous. (orig.)

Geologic considerations for the subsurface injection of naturally occurring radioactive materials (NORM): A case study

International Nuclear Information System (INIS)

Ladle, G.H.

1995-01-01

NORM waste consists of naturally occurring radioactive material associated with oil and gas operations as scale deposited in tubulars, surface piping, pumps, and other producing and processing equipment. NORM also occurs as sludge and produced sands at wellheads, transport vessels and tank bottoms. For disposal, NORM scale and sludge are separated from the tubulars and tank bottoms and ground to less than 100 microns and mixed into a slurry at the surface facility for disposal into a deep well injection interval below the Underground Sources of Drinking Water zone. This paper addresses two primary considerations: (1) subsurface geologic investigations which identify specific geologic horizons that have sufficient porosity and permeability to accept NORM slurries containing high total suspended solids concentrations, and (2) surface facility requirements. Generic and specific information, criteria, and examples are included in the paper to allow the application of the geologic principles to other areas or regions

The Predictive Value of Selection Criteria in an Urban Magnet School

Science.gov (United States)

Lohmeier, Jill Hendrickson; Raad, Jennifer

2012-01-01

The predictive value of selection criteria on outcome data from two cohorts of students (Total N = 525) accepted to an urban magnet high school were evaluated. Regression analyses of typical screening variables (suspensions, absences, metropolitan achievement tests, middle school grade point averages [GPAs], Matrix Analogies test scores, and…

The Suitable Geological Formations for Spent Fuel Disposal in Romania

International Nuclear Information System (INIS)

Marunteanu, C.; Ionita, G.; Durdun, I.

2007-01-01

Using the experience in the field of advanced countries and formerly Romanian program data, ANDRAD, the agency responsible for the disposal of radioactive wastes, started the program for spent fuel disposal in deep geological formations with a documentary analysis at the national scale. The potential geological formations properly characterized elsewhere in the world: salt, clay, volcanic tuff, granite and crystalline rocks,. are all present in Romania. Using general or specific selection criteria, we presently consider the following two areas for candidate geological formations: 1. Clay formations in two areas in the western part of Romania: (1) The Pannonian basin Socodor - Zarand, where the clay formation is 3000 m thick, with many bentonitic strata and undisturbed structure, and (2) The Eocene Red Clay on the Somes River, extending 1200 m below the surface. They both need a large investigation program in order to establish and select the required homogeneous, dry and undisturbed zones at a suitable depth. 2. Old platform green schist formations, low metamorphosed, quartz and feldspar rich rocks, in the Central Dobrogea structural unit, not far from Cernavoda NPP (30 km average distance), 3000 m thick and including many homogeneous, fine granular, undisturbed, up to 300 m thick layers. (authors)

Association between mapped vegetation and Quaternary geology on Santa Rosa Island, California

Science.gov (United States)

Cronkite-Ratcliff, C.; Corbett, S.; Schmidt, K. M.

2017-12-01

Vegetation and surficial geology are closely connected through the interface generally referred to as the critical zone. Not only do they influence each other, but they also provide clues into the effects of climate, topography, and hydrology on the earth's surface. This presentation describes quantitative analyses of the association between the recently compiled, independently generated vegetation and geologic map units on Santa Rosa Island, part of the Channel Islands National Park in Southern California. Santa Rosa Island was heavily grazed by sheep and cattle ranching for over one hundred years prior to its acquisition by the National Park Service. During this period, the island experienced significant erosion and spatial reduction and diversity of native plant species. Understanding the relationship between geology and vegetation is necessary for monitoring the recovery of native plant species, enhancing the viability of restoration sites, and understanding hydrologic conditions favorable for plant growth. Differences in grain size distribution and soil depth between geologic units support different plant communities through their influence on soil moisture, while differences in unit age reflect different degrees of pedogenic maturity. We find that unsupervised machine learning methods provide more informative insight into vegetation-geology associations than traditional measures such as Cramer's V and Goodman and Kruskal's lambda. Correspondence analysis shows that unique vegetation-geology patterns associated with beach/dune, grassland, hillslope/colluvial, and fluvial/wetland environments can be discerned from the data. By combining geology and vegetation with topographic variables, mixture models can be used to partition the landscape into multiple representative types, which then be compared with conceptual models of plant growth and succession over different landforms. Using this collection of methods, we show various ways that that Quaternary geology

The Center for Environmental Technology Innovative Technology Screening Process

International Nuclear Information System (INIS)

Bertrand, C.M.

1995-02-01

The Center for Environmental Technology's (CET) mission is to provide a fully integrated system for accelerated evaluation, development, commercialization, and public acceptance of creative environmental solutions which match the foremost demands in today's environmentally sensitive world. In short, CET will create a means to provide quick, effective solutions for environmental needs. To meet this mission objective, CET has created a unique and innovative approach to eliminating the usual barriers in developing and testing environmental technologies. The approach paves the way for these emerging, cutting-edge technologies by coordinating environmental restoration and waste management activities of industry, universities, and the government to: efficiently and effectively transfer technology to these users, provide market-driven, cost-effective technology programs to the public and DOE, and aid in developing innovative ideas by initiating efforts between DOE facilities and private industry. The central part to this mission is selecting and evaluating specific innovative technologies for demonstration and application at United States Department of Energy (DOE) installations. The methodology and criteria used for this selection, which is called the CET Innovative Technology Screening Process, is the subject of this paper. The selection criteria used for the screening process were modeled after other DOE technology transfer programs and were further developed by CET's Technology Screening and Evaluation Board (TSEB). The process benefits both CET and the proposing vendors by providing objective selection procedures based on predefined criteria. The selection process ensures a rapid response to proposing vendors, all technologies will have the opportunity to enter the selection process, and all technologies are evaluated on the same scale and with identical criteria

Quantum probability ranking principle for ligand-based virtual screening

Science.gov (United States)

Al-Dabbagh, Mohammed Mumtaz; Salim, Naomie; Himmat, Mubarak; Ahmed, Ali; Saeed, Faisal

2017-04-01

Chemical libraries contain thousands of compounds that need screening, which increases the need for computational methods that can rank or prioritize compounds. The tools of virtual screening are widely exploited to enhance the cost effectiveness of lead drug discovery programs by ranking chemical compounds databases in decreasing probability of biological activity based upon probability ranking principle (PRP). In this paper, we developed a novel ranking approach for molecular compounds inspired by quantum mechanics, called quantum probability ranking principle (QPRP). The QPRP ranking criteria would make an attempt to draw an analogy between the physical experiment and molecular structure ranking process for 2D fingerprints in ligand based virtual screening (LBVS). The development of QPRP criteria in LBVS has employed the concepts of quantum at three different levels, firstly at representation level, this model makes an effort to develop a new framework of molecular representation by connecting the molecular compounds with mathematical quantum space. Secondly, estimate the similarity between chemical libraries and references based on quantum-based similarity searching method. Finally, rank the molecules using QPRP approach. Simulated virtual screening experiments with MDL drug data report (MDDR) data sets showed that QPRP outperformed the classical ranking principle (PRP) for molecular chemical compounds.

Quantum probability ranking principle for ligand-based virtual screening.

Science.gov (United States)

Al-Dabbagh, Mohammed Mumtaz; Salim, Naomie; Himmat, Mubarak; Ahmed, Ali; Saeed, Faisal

2017-04-01

Chemical libraries contain thousands of compounds that need screening, which increases the need for computational methods that can rank or prioritize compounds. The tools of virtual screening are widely exploited to enhance the cost effectiveness of lead drug discovery programs by ranking chemical compounds databases in decreasing probability of biological activity based upon probability ranking principle (PRP). In this paper, we developed a novel ranking approach for molecular compounds inspired by quantum mechanics, called quantum probability ranking principle (QPRP). The QPRP ranking criteria would make an attempt to draw an analogy between the physical experiment and molecular structure ranking process for 2D fingerprints in ligand based virtual screening (LBVS). The development of QPRP criteria in LBVS has employed the concepts of quantum at three different levels, firstly at representation level, this model makes an effort to develop a new framework of molecular representation by connecting the molecular compounds with mathematical quantum space. Secondly, estimate the similarity between chemical libraries and references based on quantum-based similarity searching method. Finally, rank the molecules using QPRP approach. Simulated virtual screening experiments with MDL drug data report (MDDR) data sets showed that QPRP outperformed the classical ranking principle (PRP) for molecular chemical compounds.

Geologic and engineering dimensions of nuclear waste storage

International Nuclear Information System (INIS)

Hoskins, E.R.; Russell, J.E.

1983-01-01

Nuclear waste characteristics, existing and projected quantities of radioactive materials that need to be stored, various disposal or storage strategies or alternatives, geologic media under consideration, and repository construction techniques and problems are discussed. The best alternative at this time is containment in mined caverns, deep underground. There are still uncertainties in site selection criteria, in the design of underground openings, and in the prediction of both cultural and natural hazards and their effects on the repository over a 1000-year or longer time frame. It is possible to minimize the negative effects by careful site selection, although this involves more than just technical issues

Biological Evaluations of an Off-Stream Channel, Horizontal Flat-Plate Fish Screen-The Farmers Screen

Science.gov (United States)

Mesa, Matthew G.; Rose, Brien P.; Copeland, Elizabeth S.

2010-01-01

Screens are commonly installed at water diversion sites to reduce entrainment of fish. Recently, the Farmers Irrigation District in Hood River, Oregon, developed a new flat-plate screen design that offers passive operation and may result in reduced operation and installation costs to irrigators. To evaluate the performance (its biological effect on fish) of this type of screen, two size classes of juvenile coho salmon (Oncorhynchus kistuch) were released over a small version of this screen in the field-the Herman Creek screen. The performance of the screen was evaluated over a range of inflow [0.02 to 0.42 m3/s (cubic meters per second)] and diversion flows (0.02 to 0.34 m3/s) at different weir wall heights. The mean approach velocities for the screen ranged from 0 to 5 cm/s (centimeters per second) and mean sweeping velocities ranged from 36 to 178 cm/s. Water depths over the screen surface ranged from 1 to 25 centimeters and were directly related to weir wall height and inflow. Passage of juvenile coho salmon over the screen under a variety of hydraulic conditions did not severely injure them or cause delayed mortality. For all fish, the mean percentage of body surface area that was injured after passage over the screen ranged from about 0.4 to 3.0%. This occurred even though many fish contacted the screen surface during passage. No fish were observed becoming impinged on the screen surface (greater than 1 second contact with the screen). When operated within its design criteria (diversion flows of about 0.28 m3/s), the screen provided safe and effective downstream passage of juvenile salmonids under a variety of hydraulic conditions. However, we do not recommend operating the screen at inflows less than 0.14 m3/s (5 ft3/s) because water depth can get quite shallow and the screen can completely dewater, particularly at very low flows.

Italian Euromelanoma Day Screening Campaign (2005-2007) and the planning of melanoma screening strategies.

Science.gov (United States)

Seidenari, Stefania; Benati, Elisa; Ponti, Giovanni; Borsari, Stefania; Ferrari, Chiara; Albertini, Giuseppe; Altomare, Gianfranco; Arcangeli, Fabio; Aste, Nicola; Bernengo, Maria Grazia; Bongiorno, Maria Rita; Borroni, Giovanni; Calvieri, Stefano; Chimenti, Sergio; Cusano, Francesco; Fracchiolla, Claudio; Gaddoni, Giuseppe; Girolomoni, Giampiero; Guarneri, Biagio; Lanzoni, Anna; Lombardi, Mara; Lotti, Torello; Mariotti, Antonio; Marsili, Franco; Micali, Giuseppe; Parodi, Aurora; Peris, Ketty; Peserico, Andrea; Quaglino, Pietro; Santini, Marcello; Schiavon, Sergio; Tonino, Camillo; Trevisan, Giusto; Tribuzi, Paola; Valentini, Paolo; Vena, Gino A; Virgili, Annarosa

2012-01-01

Although no study has definitively shown that unfocused screening of skin cancer is effective, many campaigns have been organized with the aim of increasing awareness on melanoma risk factors. The objective of this study was to analyse the results of the Skin Cancer Screening Day in Italy during the period 2005-2007, to determine the priorities for melanoma control plans in a Mediterranean country. A total of 5002 patients were screened by dermatologists in 31 cities. Individuals who considered themselves to have many naevi and those with a family history of melanoma showed a higher number of common and atypical naevi. Ten melanomas, 20 basal cell carcinomas and two squamous cell carcinomas were histopathologically confirmed. Our observations provide the following suggestions for melanoma prevention strategies: (a) an unfocused campaign is suitable to inform the public about the importance of self-examination of the skin, but is not useful to identify a larger number of melanomas; and (b) melanoma screening campaigns should focus on a selected population, which meets rigorous risk criteria to maintain higher cost-effectiveness. The financial support to effective melanoma screening programmes could be increased, especially in southern populations where lower levels of self-surveillance and socioeconomic conditions represent risk factors for late identification of melanoma.

Destination: Geology?

Science.gov (United States)

Price, Louise

2016-04-01

"While we teach, we learn" (Roman philosopher Seneca) One of the most beneficial ways to remember a theory or concept is to explain it to someone else. The offer of fieldwork and visits to exciting destinations is arguably the easiest way to spark a students' interest in any subject. Geology at A-Level (age 16-18) in the United Kingdom incorporates significant elements of field studies into the curriculum with many students choosing the subject on this basis and it being a key factor in consolidating student knowledge and understanding. Geology maintains a healthy annual enrollment with interest in the subject increasing in recent years. However, it is important for educators not to loose sight of the importance of recruitment and retention of students. Recent flexibility in the subject content of the UK curriculum in secondary schools has provided an opportunity to teach the basic principles of the subject to our younger students and fieldwork provides a valuable opportunity to engage with these students in the promotion of the subject. Promotion of the subject is typically devolved to senior students at Hessle High School and Sixth Form College, drawing on their personal experiences to engage younger students. Prospective students are excited to learn from a guest speaker, so why not use our most senior students to engage and promote the subject rather than their normal subject teacher? A-Level geology students embarking on fieldwork abroad, understand their additional responsibility to promote the subject and share their understanding of the field visit. They will typically produce a series of lessons and activities for younger students using their newly acquired knowledge. Senior students also present to whole year groups in seminars, sharing knowledge of the location's geology and raising awareness of the exciting destinations offered by geology. Geology fieldwork is always planned, organised and led by the member of staff to keep costs low, with recent visits

Application of EU guidelines for the validation of screening methods for veterinary drugs

NARCIS (Netherlands)

Stolker, A.A.M.

2012-01-01

Commission Decision (CD) 2002/657/EC describes detailed rules for method validation within the framework of residue monitoring programmes. The approach described in this CD is based on criteria. For (qualitative) screening methods, the most important criteria is that the CCß has to be below any

Between worst and best: developing criteria to identify promising practices in health promotion and disease prevention for the Canadian Best Practices Portal.

Science.gov (United States)

Fazal, Nadia; Jackson, Suzanne F; Wong, Katy; Yessis, Jennifer; Jetha, Nina

2017-11-01

In health promotion and chronic disease prevention, both best and promising practices can provide critical insights into what works for enhancing the healthrelated outcomes of individuals and communities, and how/why these practices work in different situations and contexts. The promising practices criteria were developed using the Public Health Agency of Canada's (PHAC's) existing best practices criteria as the foundation. They were modified and pilot tested (three rounds) using published interventions. Theoretical and methodological issues and challenges were resolved via consultation and in-depth discussions with a working group. The team established a set of promising practices criteria, which differentiated from the best practices criteria via six specific measures. While a number of complex challenges emerged in the development of these criteria, they were thoroughly discussed, debated and resolved. The Canadian Best Practices Portal's screening criteria allow one to screen for both best and promising practices in the fields of public health, health promotion, chronic disease prevention, and potentially beyond.

Study on the background information for the geological disposal concept

International Nuclear Information System (INIS)

Matsui, Kazuaki; Murano, Tohru; Hirusawa, Shigenobu; Komoto, Harumi

1999-11-01

Japan Nuclear Cycle Development Institute (JNC) has published the first R and D progress report in 1992. In which the fruits of the R and D works were compiled. Since then the next step of R and D has been developing progressively in Japan. Now JNC has a plan to make the second R and D progress report until before 2000, in which information on the geological disposal of high level radioactive waste(HLW) will be presented to show the technical reliability and technical basis to contribute for the site selection or the safety-standard developments. Recognizing the importance of the social consensus to the geological disposal of international discussions in 1990's, understanding and consensus by the society are essential to the development and realization of the geological disposal of HLW. For getting social understanding and consensus, it is quite important to present the broad basis background information on the geological disposal of HLW, together with the technical basis and also the international discussion of the issues. In this report, the following studies have been done to help to prepare the background information for the 2nd R and D progress report, based on the recent informations and research and assessment works of last 2 years. These are, (1) As the part of general discussion, characteristics of HLW disposal and several issues to be considered for establishing the measures of the disposal of HLW were identified and analyzed from both practical and logical points of view. Those issues were the concept and image of the long term safety measures, the concept and criteria of geological disposal, and, safety assessment and performance assessment. (2) As the part of specific discussion, questions and concerns frequently raised by the non-specialists were taken up and 10 topics in relation to the geological disposal have been identified based on the discussion. Scientific and technical facts, consensus by the specialists on the issues, and international

Understanding the role of embarrassment in gynaecological screening: a qualitative study from the ASPIRE cervical cancer screening project in Uganda.

Science.gov (United States)

Teng, Flora F; Mitchell, Sheona M; Sekikubo, Musa; Biryabarema, Christine; Byamugisha, Josaphat K; Steinberg, Malcolm; Money, Deborah M; Ogilvie, Gina S

2014-04-11

To define embarrassment and develop an understanding of the role of embarrassment in relation to cervical cancer screening and self-collected human papillomavirus (HPV) DNA testing in Uganda. Cross-sectional, qualitative study using semistructured one-to-one interviews and focus groups. 6 key-informant health workers and 16 local women, purposively sampled. Key informant inclusion criteria: Ugandan members of the project team. Focus group inclusion criteria: woman age 30-69 years, Luganda or Swahili speaking, living or working in the target Ugandan community. unwillingness to sign informed consent. Primary and tertiary low-resource setting in Kampala, Uganda. In Luganda, embarrassment relating to cervical cancer is described in two forms. 'Community embarrassment' describes discomfort based on how a person may be perceived by others. 'Personal embarrassment' relates to shyness or discomfort with her own genitalia. Community embarrassment was described in themes relating to place of study recruitment, amount of privacy in dwellings, personal relationship with health workers, handling of the vaginal swab and misunderstanding of HPV self-collection as HIV testing. Themes of personal embarrassment related to lack of knowledge, age and novelty of the self-collection swab. Overall, embarrassment was a barrier to screening at the outset and diminished over time through education and knowledge. Fatalism regarding cervical cancer diagnosis, worry about results and stigma associated with a cervical cancer diagnosis were other psychosocial barriers described. Overcoming psychosocial barriers to screening can include peer-to-peer education, drama and media campaigns. Embarrassment and other psychosocial barriers may play a large role at the onset of a screening programme, but over time as education and knowledge increase, and the social norms around screening evolve, its role diminishes. The role of peer-to-peer education and community authorities on healthcare cannot be

Selection criteria for a radioactive waste disposal site in the Republic of South Africa

International Nuclear Information System (INIS)

Toens, P.D.; Hambleton-Jones, B.B.

1986-01-01

A program commenced in 1978 to select a suitable site for the disposal of nuclear waste in South Africa. This entailed the examination of a variety of socio-economic and earthscience related parameters over large parts of South Africa. The site selection program, for which the Geology Department of the Atomic Energy Corporation of South Africa Ltd (AEC) (previously the Nuclear Development Corporation (NUCOR)) accepted responsibility, commenced with an initial screening phase and led to the identification of potentially suitable areas by mid 1980. A site suitability phase involving regional, and subsequently detailed socio-economic, geological, geohydrological and geophysical studies in the areas identified by the screening phase was completed in December 1982. As a result of very positive indications that the district of Namaqualand was the most suitable candidate area it was possible, after further detailed investigations, to identify and purchase a site judged to be suitable for the disposal of low- and intermediate-level waste by February 1983. The area acquired measures some 10 000ha in extent and is situated 100km southeast of Springbok in the northwestern Cape and 600km north of the Koeberg nuclear power station near Cape Town

Site selection criteria for the shallow land burial of low-level radioactive waste

International Nuclear Information System (INIS)

Falconer, K.L.; Hull, L.C.; Mizell, S.A.

The shallow land burial of low-level waste must be accomplished in a manner that ensures the public and biosphere are protected from harmful amounts of radiation. This can be attained by selecting, designing, operating and closing sites such that contaminants never leave the site boundary in levels above regulatory limits. Site design, operation and closure are all functions of the characteristics of the site selected. As a result, the site selection process offers the most effective means for optimizing safe, efficient and economical low-level waste burial practices. The purpose of this document is to set forth criteria for the selection of shallow land burial sites. Criteria are standard rules, by which the ability of a site to meet waste management goals can be judged. They are comprehensive, universal, and qualitative and are applicable in any geologic environment. Site selection criteria provide the framework for the siting process

The urgent need for universally applicable simple screening procedures and diagnostic criteria for gestational diabetes mellitus – lessons from projects funded by the World Diabetes Foundation

Directory of Open Access Journals (Sweden)

Maximilian de Courten

2012-07-01

Full Text Available Background: To address the risks of adverse pregnancy outcomes and future type 2 diabetes associated with gestational diabetes mellitus (GDM, its early detection and timely treatment is essential. In the absence of an international consensus, multiple different guidelines on screening and diagnosis of GDM have existed for a long time. This may be changing with the publication of the recommendations by the International Association of Diabetes and Pregnancy Study Groups. However, none of these guidelines take into account evidence from or ground realities of resource-poor settings. Objective: This study aimed to investigate whether GDM projects supported by the World Diabetes Foundation in developing countries utilize any of the internationally recommended guidelines for screening and diagnosis of GDM, explore experiences on applicability and usefulness of the guidelines and barriers if any, in implementing the guidelines. These projects have reached out to thousands of pregnant women through capacity building and improvement of access to GDM screening and diagnosis in the developing world and therefore provide a rich field experience on the applicability of the guidelines in resource-poor settings. Design: A mixed methods approach using questionnaires and interviews was utilised to review 11 GDM projects. Two projects were conducted by the same partner; interviews were conducted in person or via phone by the first author with nine project partners and one responded via email. The interviews were analysed using content analysis. Results: The projects use seven different screening procedures and diagnostic criteria and many do not completely adhere to one guideline alone. Various challenges in adhering to the recommendations emerged in the interviews, including problems with screening women during the recommended time period, applicability of some of the listed risk factors used for (pre-screening, difficulties with reaching women for testing in

Reevaluation of 1999 Health-Based Environmental Screening Levels (HBESLs) for Chemical Warfare Agents

Energy Technology Data Exchange (ETDEWEB)

Watson, Annetta Paule [ORNL; Dolislager, Fredrick G [ORNL

2007-05-01

This report evaluates whether new information and updated scientific models require that changes be made to previously published health-based environmental soil screening levels (HBESLs) and associated environmental fate/breakdown information for chemical warfare agents (USACHPPM 1999). Specifically, the present evaluation describes and compares changes that have been made since 1999 to U.S. Environmental Protection Agency (EPA) risk assessment models, EPA exposure assumptions, as well as to specific chemical warfare agent parameters (e.g., toxicity values). Comparison was made between screening value estimates recalculated with current assumptions and earlier health-based environmental screening levels presented in 1999. The chemical warfare agents evaluated include the G-series and VX nerve agents and the vesicants sulfur mustard (agent HD) and Lewisite (agent L). In addition, key degradation products of these agents were also evaluated. Study findings indicate that the combined effect of updates and/or changes to EPA risk models, EPA default exposure parameters, and certain chemical warfare agent toxicity criteria does not result in significant alteration to the USACHPPM (1999) health-based environmental screening level estimates for the G-series and VX nerve agents or the vesicant agents HD and L. Given that EPA's final position on separate Tier 1 screening levels for indoor and outdoor worker screening assessments has not yet been released as of May 2007, the study authors find that the 1999 screening level estimates (see Table ES.1) are still appropriate and protective for screening residential as well as nonresidential sites. As such, risk management decisions made on the basis of USACHPPM (1999) recommendations do not require reconsideration. While the 1999 HBESL values are appropriate for continued use as general screening criteria, the updated '2007' estimates (presented below) that follow the new EPA protocols currently under development

Site selection factors for repositories of solid high-level and alpha-bearing wastes in geological formations

International Nuclear Information System (INIS)

1977-01-01

The purpose of this report is to provide guidelines for the selection and evaluation of suitable areas and sites for the disposal of solid high-level and alpha-bearing wastes into geological formations. This report is also intended to provide summary information on many types of geological formations underlying the land masses that might be considered as well as guidance on the geological and hydrological factors that should be investigated to demonstrate the suitability of the formations. In addition, other factors that should be considered in selecting a site for a radioactive waste repository are discussed briefly. The information, as presented, was developed to the extent of current technology for application to the evaluation of deep (greater than about 300 metres below ground level) geological formations in the selection of suitable areas for the disposal of solid or solidified high-level and alpha-bearing wastes. The extreme complexity of many geological environments and of the rock features that govern the presence and circulation of groundwater does not make it feasible to derive strict criteria for the selection of a site for a radioactive waste repository in a geological formation. Each potential repository location must be evaluated according to its own unique geological and hydrological setting. Therefore, only general guidance is offered, and this is done through discussion of the many factors that need to be considered in order to obtain the necessary assurances that the radionuclides will be confined in the geological repository over the required period of time

Site selection factors for repositories of solid high-level and alpha-bearing wastes in geological formations

Energy Technology Data Exchange (ETDEWEB)

1977-01-01

The purpose of this report is to provide guidelines for the selection and evaluation of suitable areas and sites for the disposal of solid high-level and alpha-bearing wastes into geological formations. This report is also intended to provide summary information on many types of geological formations underlying the land masses that might be considered as well as guidance on the geological and hydrological factors that should be investigated to demonstrate the suitability of the formations. In addition, other factors that should be considered in selecting a site for a radioactive waste repository are discussed briefly. The information, as presented, was developed to the extent of current technology for application to the evaluation of deep (greater than about 300 meters below ground level) geological formations in the selection of suitable areas for the disposal of solid or solidified high-level and alpha-bearing wastes. The extreme complexity of many geological environments and of the rock features that govern the presence and circulation of groundwater does not make it feasible to derive strict criteria for the selection of a site for a radioactive waste repository in a geological formation. Each potential repository location must be evaluated according to its own unique geological and hydrological setting. Therefore, only general guidance is offered, and this is done through discussion of the many factors that need to be considered in order to obtain the necessary assurances that the radionuclides will be confined in the geological repository over the required period of time.

Global Journal of Geological Sciences

African Journals Online (AJOL)

Global Journal of Geological Sciences is aimed at promoting research in all areas of Geological Sciences including geochemistry, geophysics, engineering geology, hydrogeology, petrology, mineralogy, geochronology, tectonics, mining, structural geology, marine geology, space science etc. Visit the Global Journal Series ...

Research on geological disposal: R and D concept on geological disposal

International Nuclear Information System (INIS)

1993-01-01

The objective on geological disposal of high-level radioactive wastes are to ensure the long term radiological protection of the human and his environment in accordance with current internationally agreed radiation protection principles. The principle of geological disposal is to settle the high-level wastes in deep underground so as to isolate them from the human and his environment considering the existence of groundwater. Japan is currently in the stage of assessing technical feasibility of geological disposal to the extent practicable. In accordance with the AEC (Atomic Energy Commission) policy in 1989, PNC (Power Reactor and Nuclear Fuel Development Corporation) has conducted the research and development on geological disposal in three areas: 1) studies of geological environment, 2) research and development of disposal technology, and 3) performance assessment study. (author)

Introductory Geology From the Liberal Arts Approach: A Geology-Sociology Linked Course

Science.gov (United States)

Walsh, E. O.; Davis, E.

2008-12-01

Geology can be a hard sell to college students, especially to college students attending small, liberal arts institutions in localities that lack exaggerated topography. At these schools, Geology departments that wish to grow must work diligently to attract students to the major; professors must be able to convince a wider audience of students that geology is relevant to their everyday lives. Toward this end, a Physical Geology course was linked with an introductory Sociology course through the common theme of Consumption. The same students took the two courses in sequence, beginning with the Sociology course and ending with Physical Geology; thus, students began by discussing the role of consumption in society and ended by learning about the geological processes and implications of consumption. Students were able to ascertain the importance of geology in their daily lives by connecting Earth processes to specific products they consume, such as cell phones and bottled water. Students were also able to see the connection between seemingly disparate fields of study, which is a major goal of the liberal arts. As a theme, Consumption worked well to grab the attention of students interested in diverse issues, such as environmental science or social justice. A one-hour lecture illustrating the link between sociology and geology was developed for presentation to incoming freshmen and their parents to advertise the course. Initial response has been positive, showing an increase in awareness of geological processes among students with a wide range of interests.

Engineering geology of waste disposal

International Nuclear Information System (INIS)

Bentley, S.P.

1996-01-01

This volume covers a wide spectrum of activities in the field of waste disposal. These activities range from design of new landfills and containment properties of natural clays to investigation, hazard assessment and remediation of existing landfills. Consideration is given to design criteria for hard rock quarries when used for waste disposal. In addition, an entire section concerns the geotechnics of underground repositories. This covers such topics as deep drilling, in situ stress measurement, rock mass characterization, groundwater flows and barrier design. Engineering Geology of Waste Disposal examines, in detail, the active role of engineering geologists in the design of waste disposal facilities on UK and international projects. The book provides an authoritative mix of overviews and detailed case histories. The extensive spectrum of papers will be of practical value to those geologists, engineers and environmental scientists who are directly involved with waste disposal. (UK)

Evaluation of radar imagery for geological and cartographic applications

Science.gov (United States)

Moore, Gerald K.; Sheehan, Cynthia A.

1981-01-01

The House/Senate conference report on H.R. 4930 (96th Congress), the Department of the Interior and Related Agencies Appropriations bill, 1980, stated that the U.S. Geological Survey should "begin the use of side-looking airborne radar imagery for topographic and geological mapping, and geological resource surveys in promising areas, particularly Alaska." In response to this mandate, the Survey acquired radar data and began scientific studies to analyze and interpret these data. About 70 percent of the project funding was used to acquire radar imagery and to evaluate Alaskan applications. Results of these studies indicate that radar images have a unique incremental value for certain geologic and cartographic applications but that the images are best suited for use as supplemental information sources or as primary data sources in areas of persistent cloud cover.The value of radar data is greatest for geologic mapping and resource surveys, particularly for mineral and petroleum exploration, where the objective is to locate any single feature or group of features that may control the occurrences of these resources. Radar images are considered by oil and gas companies to be worth the cost of data acquisition within a limited area of active exploration.Radar images also have incremental value for geologic site studies and hazard mapping. The need in these cases is TO inventory all geologic hazards to human life, property, resources, and the environment. For other geologic applications, radar images have a relatively small incremental value over a combination of Landsat images and aerial photographs.The value of radar images for cartographic applications is minimal, except when they are used as a substitute for aerial photographs and topographic maps in persistently cloud-covered areas. If conventional data sources are not available, radar images provide useful information on terrain relief, landforms, drainage patterns, and land cover. Screen less lithography is a low

Washington Phase II Fish Diversion Screen Evaluations in the Yakima River Basin, 2004-2005 Annual Report.

Energy Technology Data Exchange (ETDEWEB)

Vucelick, Jessica; McMichael, Geoffrey; Chamness, Mickie [Pacific Northwest National Laboratory

2006-02-01

In 2004, the Pacific Northwest National Laboratory (PNNL) evaluated 25 Phase II fish screen sites in the Yakima River Basin as part of a multi-year project for the Bonneville Power Administration on the effectiveness of fish screening devices. PNNL collected data to determine whether velocities in front of the screens and in the bypasses met the National Oceanic and Atmospheric Administration Fisheries (NOAA Fisheries, formerly the National Marine Fisheries Service (NMFS)) criteria to promote safe and timely fish passage. In addition, PNNL conducted underwater video surveys to evaluate the environmental and operational conditions of the screen sites with respect to fish passage. Based on evaluations in 2004, PNNL concluded that: (1) In general, water velocity conditions at the screen sites met fish passage criteria set by NOAA Fisheries. (2) Conditions at most facilities would be expected to provide for safe juvenile fish passage. (3) Automated cleaning brushes generally functioned properly; chains and other moving parts were typically well-greased and operative. (4) Removal of sediment buildup and accumulated leafy and woody debris could be improved at some sites. (5) Conditions at some facilities indicate that operation and/or maintenance should be modified to improve passage conditions for juvenile fish. For example, Taylor has had problems meeting bypass flow and submergence operating criteria since the main river channel shifted away from the site 2 years ago, and Fruitvale consistently has had problems meeting bypass flow criteria when the water is low. (6) Continued problems at Gleed point to design flaws. This site should be considered for redesign or replacement.

SUDOQU: a new dose model to derive criteria for surface contamination of non-food (consumer) goods, containers and conveyances

International Nuclear Information System (INIS)

Van Dillen, Teun

2015-01-01

The Fukushima nuclear accident (Japan, 11 March 2011) revealed the need for well-founded criteria for surface contamination and associated screening levels related to the import of non-food (consumer) goods, containers and conveyances. The only available European-harmonised criteria are those laid down in the IAEA transport regulations, but these criteria date back from the early 1960's and only apply to the safe transport of radioactive materials. The main problem is that a generic dose-assessment model for consumer products is missing. Therefore, RIVM (National Institute for Public Health and the Environment) developed a new methodology entitled SUDOQU (Surface Dose Quantification) to calculate the annual effective dose for both consumers and non-radiological workers, addressing issues of removability of surface contamination. The methodology can be used to derive criteria and screening levels for surface contamination and could serve as a useful tool for policy-makers and radiation-protection specialists. (authors)

Geology and recognition criteria for veinlike uranium deposits of the lower to middle Proterozoic unconformity and strata-related types. Final report

International Nuclear Information System (INIS)

Dahlkamp, F.J.; Adams, S.S.

1981-01-01

The discovery of the Rabbit Lake deposit, Saskatchewan, in 1968 and the East Alligator Rivers district, Northern Territory, Australia, in 1970 established the Lower-Middle Proterozoic veinlike-type deposits as one of the major types of uranium deposits. The term veinlike is used in order to distinguish it from the classical magmatic-hydrothermal vein or veintype deposits. The veinlike deposits account for between a quarter and a third of the Western World's proven uranium reserves. Lower-Middle Proterozoic veinlike deposits, as discussed in this report include several subtypes of deposits, which have some significantly different geologic characteristics. These various subtypes appear to have formed from various combinations of geologic processes ranging from synsedimentary uranium precipitation through some combination of diagenesis, metamorphism, metasomatism, weathering, and deep burial diagenesis. Some of the deposit subtypes are based on only one or two incompletely described examples; hence, even the classification presented in this report may be expected to change. Geologic characteristics of the deposits differ significantly between most districts and in some cases even between deposits within districts. Emphasis in this report is placed on deposit descriptions and the interpretations of the observers

Geology and recognition criteria for veinlike uranium deposits of the lower to middle Proterozoic unconformity and strata-related types. Final report

Energy Technology Data Exchange (ETDEWEB)

Dahlkamp, F.J.; Adams, S.S.

1981-01-01

The discovery of the Rabbit Lake deposit, Saskatchewan, in 1968 and the East Alligator Rivers district, Northern Territory, Australia, in 1970 established the Lower-Middle Proterozoic veinlike-type deposits as one of the major types of uranium deposits. The term veinlike is used in order to distinguish it from the classical magmatic-hydrothermal vein or veintype deposits. The veinlike deposits account for between a quarter and a third of the Western World's proven uranium reserves. Lower-Middle Proterozoic veinlike deposits, as discussed in this report include several subtypes of deposits, which have some significantly different geologic characteristics. These various subtypes appear to have formed from various combinations of geologic processes ranging from synsedimentary uranium precipitation through some combination of diagenesis, metamorphism, metasomatism, weathering, and deep burial diagenesis. Some of the deposit subtypes are based on only one or two incompletely described examples; hence, even the classification presented in this report may be expected to change. Geologic characteristics of the deposits differ significantly between most districts and in some cases even between deposits within districts. Emphasis in this report is placed on deposit descriptions and the interpretations of the observers.

Geological exploration of Angola from Sumbe to Namibe: A review at the frontier between geology, natural resources and the history of geology

Science.gov (United States)

Masse, Pierre; Laurent, Olivier

2016-01-01

This paper provides a review of the Geological exploration of the Angola Coast (from Sumbe to Namibe) from pioneer's first geological descriptions and mining inventory to the most recent publications supported by the oil industry. We focus our attention on the following periods: 1875-1890 (Paul Choffat's work, mainly), 1910-1949 (first maps at country scale), 1949-1974 (detailed mapping of the Kwanza-Namibe coastal series), 1975-2000, with the editing of the last version of the Angola geological map at 1:1 million scale and the progressive completion of previous works. Since 2000, there is a renewal in geological fieldwork publications on the area mainly due to the work of university teams. This review paper thus stands at the frontier between geology, natural resources and the history of geology. It shows how geological knowledge has progressed in time, fueled by economic and scientific reasons.

Quantifying uncertainty of geological 3D layer models, constructed with a-priori geological expertise

NARCIS (Netherlands)

Gunnink, J.J.; Maljers, D.; Hummelman, J.

2010-01-01

Uncertainty quantification of geological models that are constructed with additional geological expert-knowledge is not straightforward. To construct sound geological 3D layer models we use a lot of additional knowledge, with an uncertainty that is hard to quantify. Examples of geological expert

Adaption of the Quality Criteria Concept to Digital Radiology (invited paper)

International Nuclear Information System (INIS)

Busch, H.P.; Jaschke, W.

1998-01-01

In recent years conventional film-screen radiography has been more and more replaced by digital techniques like 'Digital Image Intensifier Radiography' and 'Digital Storage Phosphor (Selen) Radiography'. These new digital imaging methods can be used for all areas of radiography except mammography. Digital radiography offers the advantage of additional diagnostic information, digital image format, lower radiation risk to the patient and a favourable cost/benefit relation. With digital techniques, dose can be varied over a wide range without losing diagnostic information. Thus, dose can be reduced in comparison to film-screen radiography. Inadequate technique can, in certain applications, however, lead to a significant increase of dose. Therefore, special reference dose values have to be established and controlled continuously. Different possibilities of pre- and post-processing make the evaluation of image quality of digital technique more complex compared with conventional film-screen radiography. New parameters like signal to noise ratio are more appropriate in assessing image quality. However, in daily routine well known parameters like spatial resolution, contrast detectability and dose can be more easily used for the assessment of image quality of the whole imaging chain including image processing and documentation. Special guidelines for digital radiography are necessary to guarantee high image quality and to avoid overexposure and misdiagnoses. These guidelines should be based on the Quality Criteria Concept of the EC. They should include criteria for the detectability of specific anatomic details, technical parameters for good radiographic technique and imaging performance and reference dose values. Assessment of image quality by suitable phantoms and constancy testing are prerequisites for quality assurance. The activities of an European quality criteria working group in the 'Concerted Action Programme' are focused on these subjects. (author)

Benefits and harms of lung cancer screening in HIV-infected individuals with CD4+ ≥ 500: a simulation study.

Science.gov (United States)

Kong, Chung Yin; Sigel, Keith; Criss, Steven D; Sheehan, Deirdre F; Triplette, Matthew; Silverberg, Michael J; Henschke, Claudia I; Justice, Amy; Braithwaite, R Scott; Wisnivesky, Juan; Crothers, Kristina

2018-04-19

Lung cancer is the leading cause of non-AIDS-defining cancer deaths among HIV-infected individuals. Although lung cancer screening with low-dose computed tomography (LDCT) is endorsed by multiple national organizations, whether HIV-infected individuals would have similar benefit as uninfected individuals from lung cancer screening is unknown. Our objective was to determine the benefits and harms of lung cancer screening among HIV-infected individuals. We modified an existing simulation model, the Lung Cancer Policy Model, for HIV-infected patients. Veterans Aging Cohort Study, Kaiser Permanente Northern California HIV Cohort, and medical literature. Target population: HIV-infected current and former smokers. Lifetime. Population. Annual LDCT screening from ages 45, 50, or 55 until ages 72 or 77 years. Benefits assessed included lung cancer mortality reduction and life-years gained; harms assessed included numbers of LDCT examinations, false-positive results, and overdiagnosed cases. For HIV-infected patients with CD4 at least 500 and 100% antiretroviral therapy adherence, screening using the Centers for Medicare & Medicaid Services criteria (age 55-77, 30 pack-years of smoking, current smoker or quit within 15 years of screening) would reduce lung cancer mortality by 18.9%, similar to the mortality reduction of uninfected individuals. Alternative screening strategies utilizing lower screening age and/or pack-years criteria increase mortality reduction, but require more LDCT examinations. Strategies assumed 100% screening adherence. Lung cancer screening reduces mortality in HIV-infected patients with CD4 at least l500, with a number of efficient strategies for eligibility, including the current Centers for Medicare & Medicaid Services criteria.

An assessment of Movement Disorder Society Task Force diagnostic criteria for mild cognitive impairment in Parkinson's disease.

Science.gov (United States)

Uysal-Cantürk, P; Hanağası, H A; Bilgiç, B; Gürvit, H; Emre, M

2018-01-01

Cognitive impairment is one of the most disabling non-motor symptoms of Parkinson's disease. Mild cognitive impairment constitutes a major risk for the development of Parkinson's disease dementia in the course of the disease. A Movement Disorder Society Task Force proposed diagnostic criteria for mild cognitive impairment in Parkinson's disease (PD-MCI), comprising two operational levels: Level I and Level II. The objective of our study was to test the accuracy of Level I versus Level II diagnostic criteria. Eighty-six consecutive patients with Parkinson's disease were screened and 68 patients without dementia or depression were included in the study. We used the Montreal Cognitive Assessment, Mini-Mental State Examination and Addenbrooke's Cognitive Evaluation-R screening tools for Level I and an extensive neuropsychological battery for Level II assessment. We first diagnosed PD-MCI on the basis of Level II assessment and then calculated sensitivity, specificity and area under the receiver-operator characteristics curve, comparing the performance of the three screening batteries. None of the three screening batteries proposed for Level I assessment provided satisfactory combined sensitivity and specificity for detecting PD-MCI, and their performance was similar. Using the Level II criteria, 29 patients (43%) were diagnosed as having PD-MCI. Lowest cut-off levels that provided at least 80% sensitivity were 24 for the Montreal Cognitive Assessment, 29 for the Mini-Mental State Examination and 87 for the Addenbrooke's Cognitive Evaluation-R. However, specificity levels were below 80% at these cut-off levels. We conclude that Level I assessment alone using screening batteries is not sufficiently sensitive/specific to detect PD-MCI. © 2017 EAN.

Atlantic Diabetes in Pregnancy (DIP): the prevalence and outcomes of gestational diabetes mellitus using new diagnostic criteria.

LENUS (Irish Health Repository)

O'Sullivan, E P

2012-01-31

AIMS\\/HYPOTHESIS: New diagnostic criteria for gestational diabetes mellitus (GDM) have recently been published. We wished to evaluate what impact these new criteria would have on GDM prevalence and outcomes in a predominantly European population. METHODS: The Atlantic Diabetes In Pregnancy (DIP) programme performed screening for GDM in 5,500 women with an oral glucose tolerance test at 24-28 weeks. GDM was defined according to the new International Association of Diabetes and Pregnancy Study Groups (IADPSG) criteria and compared with previous WHO criteria; maternal and neonatal adverse outcomes were prospectively recorded. RESULTS: Of the participants, 12.4% and 9.4% were diagnosed with GDM using IADPSG and WHO criteria, respectively. IADPSG GDM pregnancies were associated with a statistically significant increased incidence of adverse maternal outcomes (gestational hypertension, polyhydramnios and Caesarean section) and neonatal outcomes (prematurity, large for gestational age, neonatal unit admission, neonatal hypoglycaemia and respiratory distress). The odds ratio for the development of these adverse outcomes remained significant after adjustment for maternal age, body mass index and non-European ethnicity. Those women who were classified as having normal glucose tolerance by WHO criteria but as having GDM by IADPSG criteria also had significant adverse pregnancy outcomes. CONCLUSIONS\\/INTERPRETATION: GDM prevalence is higher when using newer IADPSG, compared with WHO, criteria, and these women and their offspring experience significant adverse pregnancy outcomes. Higher rates of GDM pose a challenge to healthcare systems, but improved screening provides an opportunity to attempt to reduce the associated morbidity for mother and child.

Screening of groundwater remedial alternatives for brownfield sites: a comprehensive method integrated MCDA with numerical simulation.

Science.gov (United States)

Li, Wei; Zhang, Min; Wang, Mingyu; Han, Zhantao; Liu, Jiankai; Chen, Zhezhou; Liu, Bo; Yan, Yan; Liu, Zhu

2018-06-01

Brownfield sites pollution and remediation is an urgent environmental issue worldwide. The screening and assessment of remedial alternatives is especially complex owing to its multiple criteria that involves technique, economy, and policy. To help the decision-makers selecting the remedial alternatives efficiently, the criteria framework conducted by the U.S. EPA is improved and a comprehensive method that integrates multiple criteria decision analysis (MCDA) with numerical simulation is conducted in this paper. The criteria framework is modified and classified into three categories: qualitative, semi-quantitative, and quantitative criteria, MCDA method, AHP-PROMETHEE (analytical hierarchy process-preference ranking organization method for enrichment evaluation) is used to determine the priority ranking of the remedial alternatives and the solute transport simulation is conducted to assess the remedial efficiency. A case study was present to demonstrate the screening method in a brownfield site in Cangzhou, northern China. The results show that the systematic method provides a reliable way to quantify the priority of the remedial alternatives.

DISPOSABLE CANISTER WASTE ACCEPTANCE CRITERIA

Energy Technology Data Exchange (ETDEWEB)

R.J. Garrett

2001-07-30

The purpose of this calculation is to provide the bases for defining the preclosure limits on radioactive material releases from radioactive waste forms to be received in disposable canisters at the Monitored Geologic Repository (MGR) at Yucca Mountain. Specifically, this calculation will provide the basis for criteria to be included in a forthcoming revision of the Waste Acceptance System Requirements Document (WASRD) that limits releases in terms of non-isotope-specific canister release dose-equivalent source terms. These criteria will be developed for the Department of Energy spent nuclear fuel (DSNF) standard canister, the Multicanister Overpack (MCO), the naval spent fuel canister, the High-Level Waste (HLW) canister, the plutonium can-in-canister, and the large Multipurpose Canister (MPC). The shippers of such canisters will be required to demonstrate that they meet these criteria before the canisters are accepted at the MGR. The Quality Assurance program is applicable to this calculation. The work reported in this document is part of the analysis of DSNF and is performed using procedure AP-3.124, Calculations. The work done for this analysis was evaluated according to procedure QAP-2-0, Control of Activities, which has been superseded by AP-2.21Q, Quality Determinations and Planning for Scientific, Engineering, and Regulatory Compliance Activities. This evaluation determined that such activities are subject to the requirements of DOE/RW/0333P, Quality Assurance Requirements and Description (DOE 2000). This work is also prepared in accordance with the development plan titled Design Basis Event Analyses on DOE SNF and Plutonium Can-In-Canister Waste Forms (CRWMS M&O 1999a) and Technical Work Plan For: Department of Energy Spent Nuclear Fuel Work Packages (CRWMS M&O 2000d). This calculation contains no electronic data applicable to any electronic data management system.

Suggested non-proliferation criteria for commercial nuclear fuel cycles

International Nuclear Information System (INIS)

Laney, R.V.; Heubotter, P.R.

1978-01-01

Based on the Administration's policy to prevent nuclear weapons proliferation through diversion of fuel from commercial reactor fuel cycles, a ''benchmark'' set of nonproliferation criteria was prepared for the commercial nuclear fuel cycle. These criteria should eliminate incremental risks of proliferation beyond those inherent in the present generation of low-enriched-uranium-fueled reactors operating in a once-through mode, with internationally safeguarded storage of spent fuel. They focus on the balanced application of technical constraints consistent with the state of the technology, with minimal requirements for institutional constraints, to provide a basis for assessing the proliferation resistance of proposed fission power systems. The paper contains: (1) our perception of the nuclear energy policy and of the baseline proliferation risk accepted under this policy; (2) objectives for a reactor and fuel cycle strategy which address the technical, political, and institutional aspects of diversion and proliferation and, at the same time, satisfy the Nation's needs for efficient, timely, and economical utilization of nuclear fuel resources; (3) criteria which are responsive to these objectives and can therefore be used to screen proposed reactor and fuel cycle strategies; and (4) a rationale for these criteria

Seismic re-evaluation criteria for Bohunice V1 reconstruction

International Nuclear Information System (INIS)

Campbell, R.; Schlund, H.; Warnken, L.

2001-01-01

Bohunice V1 in Slovakia is a Russian designed two unit WWER 440, Model 230 Pressurized Water Reactor. The plant was not originally designed for earthquake. Subsequent and ongoing reassessments now confirm that the seismic hazard at the site is significant. EBO, the plant owner has contracted with a consortium lead by Siemens AG (REKON) to do major reconstruction of the plant to significantly enhance its safety systems by the addition of new systems and the upgrading of existing systems. As part of the reconstruction, a complete seismic assessment and upgrading is required for existing safety relevant structures, systems and components. It is not practical to conduct this reassessment and upgrading using criteria applied to new design of nuclear power plants. Alternate criteria may be used to achieve adequate safety goals. Utilities in the U.S. have faced several seismic issues with operating NPPs and to resolve these issues, alternate criteria have been developed which are much more cost effective than use of criteria for new design. These alternate criteria incorporate the knowledge obtained from investigation of the performance of equipment in major earthquakes and include provisions for structures and passive equipment to deform beyond the yield point, yet still provide their essential function. IAEA has incorporated features of these alternate criteria into draft Technical Guidelines for application to Bohunice V1 and V2. REKON has developed plant specific criteria and procedures for the Bohunice V1 reconstruction that incorporate major features of the U.S. developed alternate criteria, comply to local codes and which envelop the draft IAEA Technical Guidelines. Included in these criteria and procedures are comprehensive walkdown screening criteria for equipment, piping, HVAC and cable raceways, analytical criteria which include inelastic energy absorption factors defined on an element basis and testing criteria which include specific guidance on interpretation

Incidence of Complex Regional Pain Syndrome I Following Foot and Ankle Fractures Using the Budapest Criteria.

Science.gov (United States)

Bullen, Michael; Lang, Coran; Tran, Phong

2016-12-01

OBJECTIVE : Fractures are a well-recognized inciting event in the development of complex regional pain syndrome. This study aimed to prospectively determine the incidence of complex regional pain syndrome following foot and ankle fractures. METHODS : A prospective study was conducted of patients presenting to two metropolitan hospitals with plain radiograph diagnosis of fractures to the foot or ankle. Patients were initially screened by phone 3 months after injury using the validated International Association for the Study of Pain Budapest criteria. Patients who fulfilled the screening criteria were then physically examined by a pain specialist to assess clinical signs as part of the Budapest criteria. RESULTS : A total of 306 consecutive eligible patients were included. One hundred and ten patients reported at least one symptom of complex regional pain syndrome; however, only three fulfilled the minimum requirements to necessitate clinical review. Of these three, only one patient fulfilled the combination of symptom and sign criteria for a positive diagnosis according to the validated Budapest criteria. The incidence of complex regional pain syndrome following foot and ankle fracture in this study was 0.3%. CONCLUSION : Although many patients may experience vasomotor, sensory, and sudomotor disturbance following a fracture to the foot and ankle, the observed incidence of complex regional pain syndrome using a prospectively collected validated criteria is significantly lower than previously published. © 2016 American Academy of Pain Medicine. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

Hepatitis C: is there a case for universal screening in pregnancy?

LENUS (Irish Health Repository)

Martyn, F

2011-05-01

Hepatitis C (HCV) is not routinely screened for antenatally in all maternity hospitals. Most hospitals adopt a policy of targeted screening. The policy in the Coombe Women and Infants University Hospital in Dublin changed from targeted screening in 2006 to universal screening in 2007. We audited the two consecutive years. The prevalence of HCV in our antenatal population was 1.4% for 2006 (67\\/4666) when targeted screening applied and in 2007--0.71% (66\\/9222) when universal screening came into affect. One woman in 2007 would not have been detected by targeted screening--1.49% (1\\/67). Fifty five percent (37\\/67) of women were HCV-RNA positive in 2006 and 57.5% (38\\/66) were positive in 2007. We conclude that there were similar detection rates for HCV in 2006 and 2007 and that universal screening is not required if inclusive criteria for selective screening are employed but is of use in research context.

Hepatitis C: is there a case for universal screening in pregnancy?

LENUS (Irish Health Repository)

Martyn, F

2012-02-01

Hepatitis C (HCV) is not routinely screened for antenatally in all maternity hospitals. Most hospitals adopt a policy of targeted screening. The policy in the Coombe Women and Infants University Hospital in Dublin changed from targeted screening in 2006 to universal screening in 2007. We audited the two consecutive years. The prevalence of HCV in our antenatal population was 1.4% for 2006 (67\\/4666) when targeted screening applied and in 2007--0.71% (66\\/9222) when universal screening came into affect. One woman in 2007 would not have been detected by targeted screening--1.49% (1\\/67). Fifty five percent (37\\/67) of women were HCV-RNA positive in 2006 and 57.5% (38\\/66) were positive in 2007. We conclude that there were similar detection rates for HCV in 2006 and 2007 and that universal screening is not required if inclusive criteria for selective screening are employed but is of use in research context.

High intensification screen-film systems in thorax radiography: a clinical comparison

International Nuclear Information System (INIS)

Schaefer, C.B.; Sokiranski, R.; Claussen, C.D.

1995-01-01

Objective: The quality of chest images was evaluated for a conventional screen-film system, a new asymmetric screen-film system, and a new uv screen-film system. Materials and Methods: 138 Chest radiographs (69 p.a., 69 lateral) obtained with three different high intensification screen-film combinations were compared. Film density and film contrast were measured. Three readers graded the image quality according to 16 criteria. Results: The asymmetric film-screen combination Insight HC showed the lowest film contrast, the best exposure range, and a elevated film density in the mediastinal area. The asymmetric screen-film system was ranked by all three observers as being substantially better in image quality. Conclusion: Compared to conventional screen-film systems, the new screen-film systems can improve the image quality of chest radiographs. Therefore, the new high intensification screen-film combinations can be used as a low cost alternative to the Amber technique and digital radiography. (orig.) [de

Geological heritage of Morocco

International Nuclear Information System (INIS)

Elhadi, H.; Tahiri, A.

2012-01-01

Full text: The soil and subsoil of Morocco are rich in geological phenomena that bear the imprint of a history that goes back in time more than 2000 million years. Very many sites geologically remarkable exposed in accessible outcrops, with good quality remain unknown to the general public and therefore deserve to be vulgarized. It is a memory to acquaint to the present generations but also to preserve for future generations. In total, a rich geological heritage in many ways: Varied landscapes, international stratotypes, various geological structures, varied rocks, mineral associations, a huge procession of fossiles, remnants of oceanic crust (ophiolites) among oldests ones in the world (800my), etc... For this geological heritage, an approach of an overall inventory is needed, both regionally and nationally, taking into account all the skills of the earth sciences. This will put the item on the natural (geological) potentialities as a lever for sustainable regional development. For this, it is necessary to implement a strategy of ''geoconservation'' for the preservation and assessment of the geological heritage.

Siting regions for deep geological repositories. Why just here?

International Nuclear Information System (INIS)

Rieser, A.

2009-09-01

This report helps to the popularization of the Nagra works accomplished for the management and disposal of the radioactive wastes in Switzerland. The programme for management and disposal of the radioactive wastes are extensively determined by regulations. Protection of mankind and environment is the primary objective. The basic storage process is considered as having been solved. The question addressed in the report is where the facility has to be built; the site selection procedure includes five steps: 1) according to their type the wastes have to be allocated to two different repositories: for low- and intermediate-level wastes (L/ILW), and for high-level and alpha-toxic wastes (HLW); 2) the safety concept for both repositories and the requirements on the geology have to be determined; 3) large suitable geological-tectonic zones must be found where repositories could be built; 4) in these geological zones a suitable host rock has to be identified; 5) the most important spatial geological conditions of the host rock (minimum depth with respect to surface erosion, maximum depth in terms of engineering requirements, lateral extent) have to be identified. Based on these criteria, three suitable siting regions for a HLW repository were found in the North of Switzerland. The preferred host rock is Opalinus clay because of its very low permeability; it is therefore an excellent barrier against nuclide transport. In the three proposed siting regions, Opalinus clay is present in sufficient volumes at a suitable depth. For a L/ILW repository six different possible siting regions were identified, five in Northern Switzerland and one in Central Switzerland. In the three siting regions found for a possible HLW repository, it would also be possible to built a combined repository for both HLW and L/ILW wastes

Between worst and best: developing criteria to identify promising practices in health promotion and disease prevention for the Canadian Best Practices Portal

Directory of Open Access Journals (Sweden)

Nadia Fazal

2017-11-01

Full Text Available Introduction: In health promotion and chronic disease prevention, both best and promising practices can provide critical insights into what works for enhancing the healthrelated outcomes of individuals and communities, and how/why these practices work in different situations and contexts. Methods: The promising practices criteria were developed using the Public Health Agency of Canada’s (PHAC’s existing best practices criteria as the foundation. They were modified and pilot tested (three rounds using published interventions. Theoretical and methodological issues and challenges were resolved via consultation and in-depth discussions with a working group. Results: The team established a set of promising practices criteria, which differentiated from the best practices criteria via six specific measures. Conclusion: While a number of complex challenges emerged in the development of these criteria, they were thoroughly discussed, debated and resolved. The Canadian Best Practices Portal’s screening criteria allow one to screen for both best and promising practices in the fields of public health, health promotion, chronic disease prevention, and potentially beyond.

Introduction to sump screen downstream effect analysis of AP1000 nuclear power plant

International Nuclear Information System (INIS)

Zhang Qinghua; Liu Yu; Chai Guohan

2010-01-01

The design of AP1000 takes into account the potential impact of debris clogging on sump screen. In this article, the technical background of sump screen issue and the design characteristics of AP1000 to address the sump screen blockage issue are introduced. The article focuses on the 'downstream effect' analysis method, acceptance criteria and analysis result of AP1000 sump screen. Although the design of AP1000 is different with traditional PWR, the author expects to bring some reference to advance the downstream effect analysis in China through the introduction. (authors)

Geological Services Laboratory

Data.gov (United States)

Federal Laboratory Consortium — Researchers use computed tomography (CT) scanners at NETL’s Geological Services Laboratory in Morgantown, WV, to peer into geologic core samples to determine how...

Geology of Mars

International Nuclear Information System (INIS)

Soderblom, L.A.

1988-01-01

The geology of Mars and the results of the Mariner 4, 6/7, and 9 missions and the Viking mission are reviewed. The Mars chronology and geologic modification are examined, including chronological models for the inactive planet, the active planet, and crater flux. The importance of surface materials is discussed and a multispectral map of Mars is presented. Suggestions are given for further studies of the geology of Mars using the Viking data. 5 references

Expanded newborn screening: social and ethical issues.

Science.gov (United States)

Dhondt, Jean-Louis

2010-10-01

Newborn screening and genetic testing have expanded rapidly in the last decade with the advent of multiplex (e.g., tandem mass spectrometry) and/or DNA technologies. However, screening panels include a large number of disorders, which may not meet all of the traditional screening criteria, established in late 1960s, and used for years to justify screening programs. After a period of expansion driven by technological advances, many reports have reconsidered the justification of expanded programs. Many factors have contributed to test-panel discrepancies between countries. The test-panel review methodology, the way health benefits are weighed against harms, and the socioeconomic-political environment all play a role. Expansion of screening also requires reconsideration of the infrastructure (ideally, in the context of national plans for rare diseases) to support testing, counselling, education, treatment, and follow-up. Consequently, economic aspects cannot be ignored and can be a limitation for expansion. New ethical questions have emerged: risks of discrimination or stigmatization, respect of the autonomy of persons to make decisions, parental anxiety resulting from a false positive test (especially when reporting to parents screening results for untreatable conditions identified as by-products of screening), etc. For disorders where there is not yet confirmation of benefit, it may be prudent to recommend pilot screening and to have a mechanism that can be used to adapt or even to stop a program.

Report on geologic exploration activities

International Nuclear Information System (INIS)

Breslin, J.; Laughon, R.B.; Hall, R.J.; Voss, J.W.

1980-01-01

This report provides an overview of the geological exploration activities being carried out as part of the National Waste Terminal Storage (NWTS) Program, which has been established by the US Department of Energy (DOE) to develop the technology and provide the facilities for the safe, environmentally acceptable isolation of civilian high-level and transuranic nuclear wastes, including spent fuel elements, for which the Federal government is responsible. The principal programmatic emphasis is on disposal in mined geologic repositories. Explorations are being conducted or planned in various parts of the country to identify potential sites for such repositories. The work is being undertaken by three separate but coordinated NWTS project elements. Under the Basalt Waste Isolation Project (BWIP), basalt formations underlying DOE's Hanford Reservation are being investigated. Granite, tuff, and shale formations at the DOE Nevada Test Site (NTS) are being similarly studied in the Nevada Nuclear Waste Storage Investigations (NNWSI). The Office of Nuclear Waste Isolation (ONWI) is investigating domed salt formations in several Gulf Coast states and bedded salt formations in Utah and Texas. The ONWI siting studies are being expanded to include areas overlying crystalline rocks, shales, and other geohydrologic systems. The current status of these NWTS efforts, including the projected budgets for FY 1981, is summarized, and the criteria and methodology being employed in the explorations are described. The consistency of the overall effort with the recommendations presented in the Report to the President by the Interagency Review Group on Nuclear Waste Management (IRG), as well as with documents representing the national technical consensus, is discussed

Report on geologic exploration activities

International Nuclear Information System (INIS)

1980-01-01

This report provides an overview of the geological exploration activities being carried out as part of the National Waste Terminal Storage (NWTS) Program, which has been established by the US Department of Energy (DOE) to develop the technology and provide the facilities for the safe, environmentally acceptable isolation of civilian high-level and transuranic nuclear wastes, including spent fuel elements, for which the Federal government is reponsible. The principal programmatic emphasis is on disposal in mined geologic repositories. Explorations are being conducted or planned in various parts of the country to identify potential sites for such repositories. The work is being undertaken by three separate but coordinated NWTS project elements. Under the Basalt Waste Isolation Project (BWIP), basalt formations underlying DOE's Hanford Reservation are being investigated. Granite, tuff, and shale formations at the DOE Nevada Test Site (NTS) are being similarly studied in the Nevada Nuclear Waste Storage Investigations (NNWSI). The Office of Nuclear Waste Isolation (ONWI) is investigating domed salt formations in several Gulf Coast states and bedded salt formations in Utah and Texas. Th ONWI siting studies are being expanded to include areas overlying crystalline rocks, shales, and other geohydrologic systems. The current status of these NWTS efforts, including the projected budgets for FY 1981, is summarized, and the criteria and methodology being employed in the explorations are described. The consistency of the overall effort with the recommendations presented in the Report to the President by the Interagency Review Group on Nuclear Waste Management (IRG), as well as with documents representing the national technical consensus, is discussed

History of geological disposal concept (3). Implementation phase of geological disposal (2000 upward)

International Nuclear Information System (INIS)

Masuda, Sumio; Sakuma, Hideki; Umeki, Hiroyuki

2015-01-01

Important standards and concept about geological disposal have been arranged as an international common base and are being generalized. The authors overview the concept of geological disposal, and would like this paper to help arouse broad discussions for promoting the implementation plan of geological disposal projects in the future. In recent years, the scientific and technological rationality of geological disposal has been recognized internationally. With the addition of discussions from social viewpoints such as ethics, economy, etc., geological disposal projects are in the stage of starting after establishment of social consensus. As an international common base, the following consolidated and systematized items have been presented as indispensable elements in promoting business projects: (1) step-by-step approach, (2) safety case, (3) reversibility and recovery potential, and (4) trust building and communications. This paper outlines the contents of the following cases, where international common base was reflected on the geological disposal projects in Japan: (1) final disposal method and safety regulations, and (2) impact of the Great East Japan Earthquake and Fukushima Daiichi Nuclear Power Station accident on geological disposal plan. (A.O.)

Conduct of Geologic Field Work During Planetary Exploration: Why Geology Matters

Science.gov (United States)

Eppler, Dean B.

2010-01-01

The science of field geology is the investigative process of determining the distribution of rock units and structures on a planet fs surface, and it is the first-order data set that informs all subsequent studies of a planet, such as geochemistry, geochronology, geophysics, or remote sensing. For future missions to the Moon and Mars, the surface systems deployed must support the conduct of field geology if these endeavors are to be scientifically useful. This lecture discussed what field geology is all about.why it is important, how it is done, how conducting field geology informs many other sciences, and how it affects the design of surface systems and the implementation of operations in the future.

Geology's Impact on Culture

Science.gov (United States)

Pizzorusso, Ann

2017-04-01

Most people consider geology boring, static and difficult. The fields of astronomy and physics have "rebranded" themselves with exciting programs formatted so as to be readily understandable to the general public. The same thing can be done for geology. My research on geology's influence on other disciplines has resulted in a book, Tweeting da Vinci, in which I was able to show how geology affected Italy's art, architecture, medicine, religion, literature, engineering and just about everything else. The reaction to the book and my lectures by both students and the general public has been very positive, including four gold medals, with reviews and comments indicating that they never knew geology could be so exciting. The book is very user friendly, packed with facts, full-color photos, paintings, sketches and illustrations. Complex aspects of geology are presented in an easily understandable style. Widely diverse topics—such as gemology, folk remedies, grottoes, painting, literature, physics and religion—are stitched together using geology as a thread. Quoting everyone from Pliny the Elder to NASA physicist Friedemann Freund, the work is solidly backed scholarship that reads as easily as a summer novel. The book can be used in classes such as physics, chemistry, literature, art history, medicine, Classical Studies, Latin, Greek and Italian. By incorporating a "geologic perspective" in these courses, it can be perceived as a more "all encompassing" discipline and encourage more students to study it. The lectures I have given on college campuses have resulted in students seeing their own majors from a different perspective and some have even signed up for introductory geology courses. One college organized summer course to the Bay of Naples based on the book. We followed the geology as well as the culture of the area and the students were profoundly moved. To encourage dialog, the book is linked to Facebook, Twitter and Instagram. This has enabled followers from

Environmental geology and hydrology

Science.gov (United States)

Nakić, Zoran; Mileusnić, Marta; Pavlić, Krešimir; Kovač, Zoran

2017-10-01

Environmental geology is scientific discipline dealing with the interactions between humans and the geologic environment. Many natural hazards, which have great impact on humans and their environment, are caused by geological settings. On the other hand, human activities have great impact on the physical environment, especially in the last decades due to dramatic human population growth. Natural disasters often hit densely populated areas causing tremendous death toll and material damage. Demand for resources enhanced remarkably, as well as waste production. Exploitation of mineral resources deteriorate huge areas of land, produce enormous mine waste and pollute soil, water and air. Environmental geology is a broad discipline and only selected themes will be presented in the following subchapters: (1) floods as natural hazard, (2) water as geological resource and (3) the mining and mineral processing as types of human activities dealing with geological materials that affect the environment and human health.

Thyroid screening of members of the public for iodine isotopes with portable NaI detectors

International Nuclear Information System (INIS)

Hunt, John G.

2014-01-01

In the case of an accident in a nuclear power plant with radionuclide releases to the environment, members of the public with possible internal contamination with radioactive isotopes of iodine should be screened to identify cases where a more detailed evaluation and medical follow-up is necessary. Screening of large numbers of the public can be performed with a quick measuring protocol using hand held unshielded NaI based detectors giving results in cps. The screening geometry was simulated using the Monte Carlo code Visual Monte Carlo. The results show that for a geometry with the NaI detector near the skin in front of the thyroid, the interference of the gamma radiation coming from other radionuclides released in the accident either deposited in the lung or in the whole body is sufficiently low to allow thyroid screening criteria to be established. The screening criteria were developed using 5, 10 and 15 year old hybrid phantoms and for the adult male based on the ICRP reference voxel phantom. (author)

Psychological distress associated with cancer screening: A systematic review.

Science.gov (United States)

Chad-Friedman, Emma; Coleman, Sarah; Traeger, Lara N; Pirl, William F; Goldman, Roberta; Atlas, Steven J; Park, Elyse R

2017-10-15

Current national cancer screening recommendations include the potential risk of psychological harm related to screening. However, data on the relation of psychological distress to cancer screening is limited. The authors conducted a systematic review to assess psychological distress associated with cancer screening procedures. Studies that administered measures of psychological distress between 2 weeks before and 1 month after the screening procedure were included. In total, 22 eligible studies met criteria for review, including 13 observational trials and 9 randomized controlled trials. Eligible studies used a broad range of validated and unvalidated measures. Anxiety was the most commonly assessed construct and was measured using the State Trait Anxiety Inventory. Studies included breast, colorectal, prostate, lung, and cervical screening procedures. Distress was low across procedures, with the exception of colorectal screening. Distress did not vary according to the time at which distress was measured. None of the studies were conducted exclusively with the intention of assessing distress at the time of screening. Evidence of low distress during the time of cancer screening suggests that distress might not be a widespread barrier to screening among adults who undergo screening. However, more studies are needed using validated measures of distress to further understand the extent to which screening may elicit psychological distress and impede adherence to national screening recommendations. Cancer 2017;123:3882-94. © 2017 American Cancer Society. © 2017 American Cancer Society.

Potentially inappropriate medications defined by STOPP criteria and the risk of adverse drug events in older hospitalized patients.

LENUS (Irish Health Repository)

Hamilton, Hilary

2011-06-13

Previous studies have not demonstrated a consistent association between potentially inappropriate medicines (PIMs) in older patients as defined by Beers criteria and avoidable adverse drug events (ADEs). This study aimed to assess whether PIMs defined by new STOPP (Screening Tool of Older Persons\\' potentially inappropriate Prescriptions) criteria are significantly associated with ADEs in older people with acute illness.

Users’ Expectation from the User Interface Screen of an Academic Digital Library

Directory of Open Access Journals (Sweden)

Akbar Majidi

2010-09-01

Full Text Available The present paper investigates the E-learner’s expectations concerning the features incorporated within the user interface screen of an academic digital library. A researcher-made questionnaire was used for the survey. The sample was taken from the E-learners using this technology in Iranian universities. 200 questionnaires were distributed. The data analysis showed a general consensus about the priority of comprehensibility of the terms used in the User Interface Screen (uis as well as the display features and clarity of the navigational functions as the usability criteria for UIS. ANOVA analysis indicated that, with the exception of navigation and guidance functions, there was no significance with respect to three categories of students. In other words, all students had similar expectations and their ICT skill is not a factor influencing the prioritization of these criteria. The results further indicated that except for the browsing page, there is no significant difference between novice, intermediate and advanced students with respect to search screen features.

Geologic Time.

Science.gov (United States)

Newman, William L.

One of a series of general interest publications on science topics, the booklet provides those interested in geologic time with an introduction to the subject. Separate sections discuss the relative time scale, major divisions in geologic time, index fossils used as guides for telling the age of rocks, the atomic scale, and the age of the earth.…

OneGeology-Europe: architecture, portal and web services to provide a European geological map

Science.gov (United States)

Tellez-Arenas, Agnès.; Serrano, Jean-Jacques; Tertre, François; Laxton, John

2010-05-01

OneGeology-Europe is a large ambitious project to make geological spatial data further known and accessible. The OneGeology-Europe project develops an integrated system of data to create and make accessible for the first time through the internet the geological map of the whole of Europe. The architecture implemented by the project is web services oriented, based on the OGC standards: the geological map is not a centralized database but is composed by several web services, each of them hosted by a European country involved in the project. Since geological data are elaborated differently from country to country, they are difficult to share. OneGeology-Europe, while providing more detailed and complete information, will foster even beyond the geological community an easier exchange of data within Europe and globally. This implies an important work regarding the harmonization of the data, both model and the content. OneGeology-Europe is characterised by the high technological capacity of the EU Member States, and has the final goal to achieve the harmonisation of European geological survey data according to common standards. As a direct consequence Europe will make a further step in terms of innovation and information dissemination, continuing to play a world leading role in the development of geosciences information. The scope of the common harmonized data model was defined primarily by the requirements of the geological map of Europe, but in addition users were consulted and the requirements of both INSPIRE and ‘high-resolution' geological maps were considered. The data model is based on GeoSciML, developed since 2006 by a group of Geological Surveys. The data providers involved in the project implemented a new component that allows the web services to deliver the geological map expressed into GeoSciML. In order to capture the information describing the geological units of the map of Europe the scope of the data model needs to include lithology; age; genesis and

Inter-Rater Reliability and Downstream Financial Implications of Electrocardiography Screening in Young Athletes.

Science.gov (United States)

Dhutia, Harshil; Malhotra, Aneil; Yeo, Tee Joo; Ster, Irina Chis; Gabus, Vincent; Steriotis, Alexandros; Dores, Helder; Mellor, Greg; García-Corrales, Carmen; Ensam, Bode; Jayalapan, Viknesh; Ezzat, Vivienne Anne; Finocchiaro, Gherardo; Gati, Sabiha; Papadakis, Michael; Tome-Esteban, Maria; Sharma, Sanjay

2017-08-01

Preparticipation screening for cardiovascular disease in young athletes with electrocardiography is endorsed by the European Society of Cardiology and several major sporting organizations. One of the concerns of the ECG as a screening test in young athletes relates to the potential for variation in interpretation. We investigated the degree of variation in ECG interpretation in athletes and its financial impact among cardiologists of differing experience. Eight cardiologists (4 with experience in screening athletes) each reported 400 ECGs of consecutively screened young athletes according to the 2010 European Society of Cardiology recommendations, Seattle criteria, and refined criteria. Cohen κ coefficient was used to calculate interobserver reliability. Cardiologists proposed secondary investigations after ECG interpretation, the costs of which were based on the UK National Health Service tariffs. Inexperienced cardiologists were more likely to classify an ECG as abnormal compared with experienced cardiologists (odds ratio, 1.44; 95% confidence interval, 1.03-2.02). Modification of ECG interpretation criteria improved interobserver reliability for categorizing an ECG as abnormal from poor (2010 European Society of Cardiology recommendations; κ=0.15) to moderate (refined criteria; κ=0.41) among inexperienced cardiologists; however, interobserver reliability was moderate for all 3 criteria among experienced cardiologists (κ=0.40-0.53). Inexperienced cardiologists were more likely to refer athletes for further evaluation compared with experienced cardiologists (odds ratio, 4.74; 95% confidence interval, 3.50-6.43) with poorer interobserver reliability (κ=0.22 versus κ=0.47). Interobserver reliability for secondary investigations after ECG interpretation ranged from poor to fair among inexperienced cardiologists (κ=0.15-0.30) and fair to moderate among experienced cardiologists (κ=0.21-0.46). The cost of cardiovascular evaluation per athlete was $175 (95

Great Basin geologic framework and uranium favorability

International Nuclear Information System (INIS)

Larson, L.T.; Beal, L.H.

1978-01-01

Work on this report has been done by a team of seven investigators assisted over the project span by twenty-three undergraduate and graduate students from May 18, 1976 to August 19, 1977. The report is presented in one volume of text, one volume or Folio of Maps, and two volumes of bibliography. The bibliography contains approximately 5300 references on geologic subjects pertinent to the search for uranium in the Great Basin. Volume I of the bibliography lists articles by author alphabetically and Volume II cross-indexes these articles by location and key word. Chapters I through IV of the Text volume and accompanying Folio Map Sets 1, 2, 3, 4, and 5, discuss the relationship of uranium to rock and structural environments which dominate the Great Basin. Chapter 5 and Map Sets 6 and 7 provide a geochemical association/metallogenic grouping of mineral occurrences in the Great Basin along with information on rock types hosting uranium. Chapter VI summarizes the results of a court house claim record search for 'new' claiming areas for uranium, and Chapter VII along with Folio Map Set 8 gives all published geochronological data available through April 1, 1977 on rocks of the Great Basin. Chapter VIII provides an introduction to a computer analysis of characteristics of certain major uranium deposits in crystalline rocks (worldwide) and is offered as a suggestion of what might be done with uranium in all geologic environments. We believe such analysis will assist materially in constructing exploration models. Chapter IX summarizes criteria used and conclusions reached as to the favorability of uranium environments which we believe to exist in the Great Basin and concludes with recommendations for both exploration and future research. A general summary conclusion is that there are several geologic environments within the Great Basin which have considerable potential and that few, if any, have been sufficiently tested

Hit Identification and Optimization in Virtual Screening: Practical Recommendations Based Upon a Critical Literature Analysis

Science.gov (United States)

Zhu, Tian; Cao, Shuyi; Su, Pin-Chih; Patel, Ram; Shah, Darshan; Chokshi, Heta B.; Szukala, Richard; Johnson, Michael E.; Hevener, Kirk E.

2013-01-01

A critical analysis of virtual screening results published between 2007 and 2011 was performed. The activity of reported hit compounds from over 400 studies was compared to their hit identification criteria. Hit rates and ligand efficiencies were calculated to assist in these analyses and the results were compared with factors such as the size of the virtual library and the number of compounds tested. A series of promiscuity, drug-like, and ADMET filters were applied to the reported hits to assess the quality of compounds reported and a careful analysis of a subset of the studies which presented hit optimization was performed. This data allowed us to make several practical recommendations with respect to selection of compounds for experimental testing, defining hit identification criteria, and general virtual screening hit criteria to allow for realistic hit optimization. A key recommendation is the use of size-targeted ligand efficiency values as hit identification criteria. PMID:23688234

Hit identification and optimization in virtual screening: practical recommendations based on a critical literature analysis.

Science.gov (United States)

Zhu, Tian; Cao, Shuyi; Su, Pin-Chih; Patel, Ram; Shah, Darshan; Chokshi, Heta B; Szukala, Richard; Johnson, Michael E; Hevener, Kirk E

2013-09-12

A critical analysis of virtual screening results published between 2007 and 2011 was performed. The activity of reported hit compounds from over 400 studies was compared to their hit identification criteria. Hit rates and ligand efficiencies were calculated to assist in these analyses, and the results were compared with factors such as the size of the virtual library and the number of compounds tested. A series of promiscuity, druglike, and ADMET filters were applied to the reported hits to assess the quality of compounds reported, and a careful analysis of a subset of the studies that presented hit optimization was performed. These data allowed us to make several practical recommendations with respect to selection of compounds for experimental testing, definition of hit identification criteria, and general virtual screening hit criteria to allow for realistic hit optimization. A key recommendation is the use of size-targeted ligand efficiency values as hit identification criteria.

Geologic mapping of Kentucky; a history and evaluation of the Kentucky Geological Survey--U.S. Geological Survey Mapping Program, 1960-1978

Science.gov (United States)

Cressman, Earle Rupert; Noger, Martin C.

1981-01-01

In 1960, the U.S. Geological Survey and the Kentucky Geological Survey began a program to map the State geologically at a scale of 1:24,000 and to publish the maps as 707 U.S. Geological Survey Geologic Quadrangle Maps. Fieldwork was completed by the spring of 1977, and all maps were published by December 1978. Geologic mapping of the State was proposed by the Kentucky Society of Professional Engineers in 1959. Wallace W. Hagan, Director and State Geologist of the Kentucky Geological Survey, and Preston McGrain, Assistant State Geologist, promoted support for the proposal among organizations such as Chambers of Commerce, industrial associations, professional societies, and among members of the State government. It was also arranged for the U.S. Geological Survey to supply mapping personnel and to publish the maps; the cost would be shared equally by the two organizations. Members of the U.S. Geological Survey assigned to the program were organized as the Branch of Kentucky Geology. Branch headquarters, including an editorial staff, was at Lexington, Ky., but actual mapping was conducted from 18 field offices distributed throughout the State. The Publications Division of the U.S. Geological Survey established a cartographic office at Lexington to prepare the maps for publication. About 260 people, including more than 200 professionals, were assigned to the Branch of Kentucky Geology by the U.S. Geological Survey at one time or another. The most geologists assigned any one year was 61. To complete the mapping and ancillary studies, 661 professional man-years were required, compared with an original estimate of 600 man-years. A wide variety of field methods were used, but most geologists relied on the surveying altimeter to obtain elevations. Surface data were supplemented by drill-hole records, and several dozen shallow diamond-drill holes were drilled to aid the mapping. Geologists generally scribed their own maps, with a consequent saving of publication costs

Near-dome geologic findings - Richton Dome, Mississippi: annual status report for FY 83

International Nuclear Information System (INIS)

1984-10-01

Basin Analysis is a study of the regional and local stratigraphic, tectonic, and salt-tectonic conditions that influenced the development of the Mississippi Salt Basin and Richton Dome, an element within that basin. During FY 83, work was concentrated on the local area surrounding Richton Dome and included the writing of the Midyear FY 83 Richton Dome Screening and Suitability Review, input to the Site Characterization Plan that is being prepared by the Southern Region Geologic Project Manager, and initial development of a near-dome geologic model. The geologic model was compiled using information from approximately 300 oil and gas well geophysical logs and 128 line km (80 line mi) of seismic-reflection profiles. In addition to analysis and interpretation of the logs and profiles, stratigraphic data from each were assembled in a computer-based file and were used to produce computer-generated structural contour maps. Major findings from the analyses include a new configuration for the northern end of Richton Dome and improved definitions of near-dome faults and the rim syncline on the northern and eastern flanks of Richton Dome. 4 references, 6 figures

Geologic Framework Model (GFM2000)

International Nuclear Information System (INIS)

T. Vogt

2004-01-01

The purpose of this report is to document the geologic framework model, version GFM2000 with regard to input data, modeling methods, assumptions, uncertainties, limitations, and validation of the model results, and the differences between GFM2000 and previous versions. The version number of this model reflects the year during which the model was constructed. This model supersedes the previous model version, documented in Geologic Framework Model (GFM 3.1) (CRWMS M and O 2000 [DIRS 138860]). The geologic framework model represents a three-dimensional interpretation of the geology surrounding the location of the monitored geologic repository for spent nuclear fuel and high-level radioactive waste at Yucca Mountain. The geologic framework model encompasses and is limited to an area of 65 square miles (168 square kilometers) and a volume of 185 cubic miles (771 cubic kilometers). The boundaries of the geologic framework model (shown in Figure 1-1) were chosen to encompass the exploratory boreholes and to provide a geologic framework over the area of interest for hydrologic flow and radionuclide transport modeling through the unsaturated zone (UZ). The upper surface of the model is made up of the surface topography and the depth of the model is constrained by the inferred depth of the Tertiary-Paleozoic unconformity. The geologic framework model was constructed from geologic map and borehole data. Additional information from measured stratigraphic sections, gravity profiles, and seismic profiles was also considered. The intended use of the geologic framework model is to provide a geologic framework over the area of interest consistent with the level of detailed needed for hydrologic flow and radionuclide transport modeling through the UZ and for repository design. The model is limited by the availability of data and relative amount of geologic complexity found in an area. The geologic framework model is inherently limited by scale and content. The grid spacing used in

Geologic Framework Model (GFM2000)

Energy Technology Data Exchange (ETDEWEB)

T. Vogt

2004-08-26

The purpose of this report is to document the geologic framework model, version GFM2000 with regard to input data, modeling methods, assumptions, uncertainties, limitations, and validation of the model results, and the differences between GFM2000 and previous versions. The version number of this model reflects the year during which the model was constructed. This model supersedes the previous model version, documented in Geologic Framework Model (GFM 3.1) (CRWMS M&O 2000 [DIRS 138860]). The geologic framework model represents a three-dimensional interpretation of the geology surrounding the location of the monitored geologic repository for spent nuclear fuel and high-level radioactive waste at Yucca Mountain. The geologic framework model encompasses and is limited to an area of 65 square miles (168 square kilometers) and a volume of 185 cubic miles (771 cubic kilometers). The boundaries of the geologic framework model (shown in Figure 1-1) were chosen to encompass the exploratory boreholes and to provide a geologic framework over the area of interest for hydrologic flow and radionuclide transport modeling through the unsaturated zone (UZ). The upper surface of the model is made up of the surface topography and the depth of the model is constrained by the inferred depth of the Tertiary-Paleozoic unconformity. The geologic framework model was constructed from geologic map and borehole data. Additional information from measured stratigraphic sections, gravity profiles, and seismic profiles was also considered. The intended use of the geologic framework model is to provide a geologic framework over the area of interest consistent with the level of detailed needed for hydrologic flow and radionuclide transport modeling through the UZ and for repository design. The model is limited by the availability of data and relative amount of geologic complexity found in an area. The geologic framework model is inherently limited by scale and content. The grid spacing used in the

Development of JNC geological disposal technical information integration system for geological environment field

International Nuclear Information System (INIS)

Tsuchiya, Makoto; Ueta, Shinzo; Ohashi, Toyo

2004-02-01

Enormous data on geology, geological structure, hydrology, geochemistry and rock properties should be obtained by various investigation/study in the geological disposal study. Therefore, 'JNC Geological Disposal Technical Information Integration System for Geological Environment Field' was developed in order to manage these data systematically and to support/promote the use of these data for the investigators concerned. The system is equipped with data base to store the information of the works and the background information of the assumptions built up in the works on each stage of data flow ('instigative', → 'data sampling' → interpretation' → conceptualization/modeling/simulation' → 'output') in the geological disposal study. In this system the data flow is shown as 'plan' composed of task' and 'work' to be done in the geological disposal study. It is possible to input the data to the database and to refer data from the database by using GUI that shows the data flow as 'plan'. The system was installed to the server computer possessed by JNC and the system utilities were checked on both the server computer and client computer also possessed by JNC. (author)

Towards transparent, proportionate and deliverable regulation for geological disposal

International Nuclear Information System (INIS)

2010-01-01

As part of its activities, the Regulators' Forum of the NEA Radioactive Waste Management Committee has been examining the regulatory criteria for the long-term performance of geological disposal. In this context, it organised a workshop entitled 'Towards Transparent, Proportionate and Deliverable Regulation for Geological Disposal', which served to verify current status and needs. Participants included regulators, implementers, policy makers, R and D specialists and academics. Themes addressed included duties to future generations, timescales for regulation, stepwise decision making, roles of optimisation and best available techniques (BAT), multiple lines of reasoning, safety and performance indicators, recognition of uncertainties and the importance of stakeholder interactions. The workshop highlighted the significant amount of work accomplished over the past decade, but also identified important differences between national regulations even if these are not in contradiction with international guidance. Also highlighted was the importance of R and D carried out on behalf of the regulator. In addition to the contributed papers, these proceedings trace the numerous discussions that formed an integral part of the workshop. They constitute an important and unique documentary basis for researchers and radioactive waste management specialists

Developing Autism Screening Criteria for the Brief Infant Toddler Social Emotional Assessment (BITSEA)

Science.gov (United States)

Giserman Kiss, Ivy; Feldman, Melanie S.; Sheldrick, R. Christopher; Carter, Alice S.

2017-01-01

There is a critical need for evidence-based, broadband behavioral, and ASD screening measures for use in pediatric and early educational settings to ensure that young children at risk for developing social-emotional disorders and/or ASD are provided with early intervention services to optimize long-term outcomes. The BITSEA is a 42-item screener…

Barrier island facies models and recognition criteria

Science.gov (United States)

Mulhern, J.; Johnson, C. L.

2017-12-01

Barrier island outcrops record transgressive shoreline motion at geologic timescales, providing integral clues to understanding how coastlines respond to rising sea levels. However, barrier island deposits are difficult to recognize. While significant progress has been made in understanding the modern coastal morphodynamics, this insight is not fully leveraged in existing barrier island facies models. Excellent outcrop exposures of the paralic Upper Cretaceous Straight Cliffs Formation of southern Utah provide an opportunity to revise facies models and recognition criteria for barrier island deposits. Preserved barrier islands are composed of three main architectural elements (shorefaces, tidal inlets, and tidal channels) which occur independently or in combination to create larger-scale barrier island deposits. Barrier island shorefaces record progradation, while barrier island tidal inlets record lateral migration, and barrier island tidal channels record aggradation within the tidal inlet. Four facies associations are used to describe and characterize these barrier island architectural elements. Barrier islands occur in association with backarrier fill and internally contain lower and upper shoreface, high-energy upper shoreface, and tidal channel facies. Barrier islands bound lagoons or estuaries, and are distinguished from other shoreface deposits by their internal facies and geometry, association with backbarrier facies, and position within transgressive successions. Tidal processes, in particular tidal inlet migration and reworking of the upper shoreface, also distinguish barrier island deposits. Existing barrier island models highlight the short term heterogeneous and dynamic nature of barrier island systems, yet overlook processes tied to geologic time scales, such as multi-directional motion, erosion, and reworking, and their expressions in preserved barrier island strata. This study uses characteristic outcrop expressions of barrier island successions to

Audit of cardiac pathology detection using a criteria-based perioperative echocardiography service.

Science.gov (United States)

Faris, J G; Hartley, K; Fuller, C M; Langston, R B; Royse, C F; Veltman, M G

2012-07-01

Transthoracic echocardiography is often used to screen patients prior to non-cardiac surgery to detect conditions associated with perioperative haemodynamic compromise and to stratify risk. However, anaesthetists' use of echocardiography is quite variable. A consortium led by the American College of Cardiology Foundation has developed appropriate use criteria for echocardiography. At Joondalup Hospital in Western Australia, we have used these criteria to order echocardiographic studies in patients attending our anaesthetic pre-admission clinic. We undertook this audit to determine the incidence of significant echocardiographic findings using this approach. In a 22-month period, 606 transthoracic echocardiographic studies were performed. This represented 8.7% of clinic attendees and 1.7% of all surgical patients. In about two-thirds of the patients, the indication for echocardiography was identified on the basis of a telephone screening questionnaire. The most common indications were poor exercise tolerance (27.4%), ischaemic heart disease (20.9%) and cardiac murmurs (16.3%). Over 26% of patients studied had significant cardiac pathology (i.e. moderate or severe echocardiographic findings), most importantly moderate or severe aortic stenosis (8.6%), poor left ventricular function (7.1%), a regional wall motion abnormality (4.3%) or moderate or severe mitral regurgitation (4.1%). Using appropriate use criteria to guide ordering transthoracic echocardiography studies led to a high detection rate of clinically important cardiac pathology in our perioperative service.

Regional and site geological frameworks : proposed Deep Geologic Repository, Bruce County, Ontario

Energy Technology Data Exchange (ETDEWEB)

Raven, K.; Sterling, S.; Gaines, S.; Wigston, A. [Intera Engineering Ltd., Ottawa, ON (Canada); Frizzell, R. [Nuclear Waste Management Organization, Toronto, ON (Canada)

2009-07-01

The Nuclear Waste Management Organization is conducting geoscientific studies on behalf of Ontario Power Generation into the proposed development of a Deep Geologic Repository (DGR) for low and intermediate level radioactive waste (L and ILW) at the Bruce site, near Tiverton, Ontario. This paper presented a regional geological framework for the site that was based on a review of regional drilling; structural geology; paleozoic stratigraphy and sedimentology; a 3D geological framework model; a DGR geological site characterization model; bedrock stratigraphy and marker beds; natural fracture frequency data; and formation predictability. The studies have shown that the depth, thickness, orientation and rock quality of the 34 rock formations, members or units that comprise the 840 m thick Paleozoic bedrock sequence at the Bruce site are very uniform and predictable over distances of several kilometres. The proposed DGR will be constructed as an engineered facility comprising a series of underground emplacement rooms at a depth of 680 metres below ground within argillaceous limestones. The geoscientific studies are meant to provide a basis for the development of descriptive geological, hydrogeological and geomechanical models of the DGR site that will facilitate environmental and safety assessments. 11 refs., 3 tabs., 9 figs.

Psychometric Evaluation of a Brief Parent- and Teacher-Rated Screen for Children at Risk of Conduct Disorder

Science.gov (United States)

Duncombe, Melissa E.; Havighurst, Sophie S.; Holland, Kerry A.; Frankling, Emma J.

2012-01-01

This study examined the psychometric properties of the Conduct Problems Risk Screen (CPRS), a seven-item screen derived from DSM-IV-TR criteria that can be completed by parents or teachers. The sample consisted of 4,752 Australian five- to nine-year-old primary school children. The results showed the parent and teacher screens had very good…

Socioeconomic disparities in access to a hepatocellular carcinoma screening program in Brazil

Directory of Open Access Journals (Sweden)

Izabelle Venturini Signorelli

Full Text Available OBJECTIVES: Cirrhotic patients must receive an abdominal ultrasound every 6 months as part of hepatocellular carcinoma (HCC screening. The aim of this study was to assess if HCC screening was performed as recommended by the literature and to observe the differences between the private and public services in Brazil. METHODS: We analyzed data from the HCC screenings of 253 cirrhotic patients from the University Hospital (n=177 and private sector (n=76 in Vitória, ES, Brazil. RESULTS: Ultrasound screening was performed every 13.1 months on average (SD 9.02. In 37 out of 253 patients, the screenings were performed close to the recommended frequency; 16 were performed every 6 months, and 21 were mostly performed during the follow-up period every 6 months. In the remaining 216 cases, ultrasounds were not performed according to the guidelines; for 106 patients, less than 50% of all ultrasounds were performed every 6 months and 110 patients showed an interval greater than one year. Patients from the private sector received ultrasound screenings near the ideal in 28.9% of cases, while patients from the University Hospital received ultrasounds in only 8.4% of cases (p<0.0001. HCC was diagnosed in 30 patients (11.8%. For these 30 patients, 11 screenings were properly performed within 6 months (36.6% and only 1 out of the 11 (9% met the criteria for transplant. In the remaining 19 patients who did not receive the screening within 6 months, 6 (31.5% did not meet the criteria for transplant. CONCLUSION: HCC screening in our environment was irregularly performed, mainly in the public service setting, which prevented early diagnosis in a large number of patients.

Development of site suitability criteria for the high level waste repository for Lawrence Livermore Laboratories

International Nuclear Information System (INIS)

1977-06-01

Results of our mining, geological and geotechnical studies provided in support of the development of site suitability criteria for the high level waste repository are presented. The primary purpose of the work was the identification and development of appropriate geotechnical descriptors and coefficients required for the Site Suitability Repository Model. This model was developed by The Analytic Sciences Corporation (TASC) of Reading, Massachusetts and is not described in this report

Development of site suitability criteria for the high level waste repository for Lawrence Livermore Laboratories

Energy Technology Data Exchange (ETDEWEB)

1977-06-01

Results of our mining, geological and geotechnical studies provided in support of the development of site suitability criteria for the high level waste repository are presented. The primary purpose of the work was the identification and development of appropriate geotechnical descriptors and coefficients required for the Site Suitability Repository Model. This model was developed by The Analytic Sciences Corporation (TASC) of Reading, Massachusetts and is not described in this report.

Design criteria for mobile phones: a teenagers perspective.

CSIR Research Space (South Africa)

Batchelor, J

2009-09-01

Full Text Available on mobile phones without blindly following criteria as observed - because there was no anchor they had to set the benchmarks for themselves. A student went even further, reflecting on long-term prospects of the project, remarking: “It is a project...-suited to mobile phones, due to obvious limitations of screen size and resolution, audio and memory restrictions. Low cost and affordable mobile phones in Africa are developing a new conduit for learning, and are gradually influencing the way we view...

Recent progress of highly efficient in vivo biological screening for novel agrochemicals in China.

Science.gov (United States)

Li, Baoju; Yuan, Huizhu; Fang, Jichao; Tao, Liming; Huang, Qingchun; Qian, Xuhong; Fan, Zhijin

2010-03-01

This paper describes the recent progress of in vivo biological screening for pesticides in China. According to the criteria, including the severity of damage caused by pests and the economic value of the crops, the investigated insects, pathogens, herbs and other species in the agricultural field were selected as the main screening targets for pesticides. Corresponding in vivo microscreening methods have been established and applied in the pesticide screening procedure, which has higher reproducibility, a shorter time and greater efficiency that offset the drawbacks of conventional methods for pesticide screening.

Screening for subtle chromosomal rearrangements in an Egyptian ...

African Journals Online (AJOL)

A descriptive study was carried out to screen for subtle chromosomal rearrangements in a group of Egyptian children with idiopathic mental retardation (IMR) to estimate its frequency if detected. The study enrolled 30 patients with IMR, with the perquisite criteria of being <18 years at referral, their IQ <70, and manifesting at ...

Assessing correlations between geological hazards and health outcomes: Addressing complexity in medical geology.

Science.gov (United States)

Wardrop, Nicola Ann; Le Blond, Jennifer Susan

2015-11-01

The field of medical geology addresses the relationships between exposure to specific geological characteristics and the development of a range of health problems: for example, long-term exposure to arsenic in drinking water can result in the development of skin conditions and cancers. While these relationships are well characterised for some examples, in others there is a lack of understanding of the specific geological component(s) triggering disease onset, necessitating further research. This paper aims to highlight several important complexities in geological exposures and the development of related diseases that can create difficulties in the linkage of exposure and health outcome data. Several suggested approaches to deal with these complexities are also suggested. Long-term exposure and lengthy latent periods are common characteristics of many diseases related to geological hazards. In combination with long- or short-distance migrations over an individual's life, daily or weekly movement patterns and small-scale spatial heterogeneity in geological characteristics, it becomes problematic to appropriately assign exposure measurements to individuals. The inclusion of supplementary methods, such as questionnaires, movement diaries or Global Positioning System (GPS) trackers can support medical geology studies by providing evidence for the most appropriate exposure measurement locations. The complex and lengthy exposure-response pathways involved, small-distance spatial heterogeneity in environmental components and a range of other issues mean that interdisciplinary approaches to medical geology studies are necessary to provide robust evidence. Copyright © 2015. Published by Elsevier Ltd.

Screening for PTSD among detained adolescents: Implications of the changes in the DSM-5.

Science.gov (United States)

Modrowski, Crosby A; Bennett, Diana C; Chaplo, Shannon D; Kerig, Patricia K

2017-01-01

Screening for posttraumatic stress disorder (PTSD) is highly relevant for youth involved in the juvenile justice system given their high rates of trauma exposure and posttraumatic stress symptoms. However, to date, no studies have investigated the implications of the recent revisions to the Diagnostic and Statistical Manual for Mental Disorders (5th ed., DSM-5; American Psychiatric Association [APA], 2013) diagnostic criteria for PTSD for screening in this population. To this end, the present study compared PTSD screening rates using the Diagnostic and Statistical Manual of Mental Disorders (4th ed., text rev., DSM-IV-TR; APA, 2013) versus DSM-5 criteria in a group of detained adolescents. Participants included 209 youth (60 girls) aged 13-19 (M = 15.97, SD = 1.24). Youth completed measures of lifetime trauma exposure and past-month posttraumatic stress symptoms. Over 95% of youth in the sample reported exposure to at least 1 type of traumatic event. Approximately 19.60% of the sample screened positive for PTSD according to the DSM-5 compared to 17.70% according to the DSM-IV-TR. Girls were more likely than boys to screen positive for PTSD according to the DSM-IV-TR compared to the DSM-5. The main factors accounting for the differences in screening rates across the versions of PTSD criteria involved the removal of Criterion A2 from the DSM-5, the separation of avoidance symptoms (Criterion C) into their own cluster, the addition of a cluster involving negative alterations in cognitions and mood (Criterion D), and revisions to the cluster of arousal symptoms (Criterion E). Future research should continue to investigate gender differences in PTSD symptoms in youth and consider the implications of these diagnostic changes for the accurate diagnosis and referral to treatment of adolescents who demonstrate posttraumatic stress reactions. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

Colonoscopy conversion after flexible sigmoidoscopy screening: results from the UK bowel scope screening programme.

Science.gov (United States)

Siau, Keith; Yew, Andrew; Ishaq, Sauid; Jewes, Sarah; Shetty, Sharan S; Brookes, Matthew; Veitch, Andrew; McKaig, Brian; Murugananthan, Aravinth

2017-12-05

In the UK Bowel Scope screening programme (BSSP), patients progress to colonoscopy based on high-risk features on flexible sigmoidoscopy (FS). To assess practice of colonoscopy conversion and predictors of additional adenoma detection on colonoscopy. The Bowel Cancer Screening database was interrogated and collated with endoscopic and histological findings from patients undergoing colonoscopy following FS between August 2013 and August 2016. Multivariate analysis was performed to identify predictors of new adenomas. Wolverhampton bowel cancer screening centre, covering Wolverhampton, Dudley, Cannock and Walsall, with a combined catchment population of 1 million. This is the first UK site to fully roll-out BSSP. FS was performed on 11,711 patients, with an adenoma detection rate (ADR) of 8.5%, and conversion to colonoscopy in 421 (3.6%). The additional ADR at colonoscopy was 35.2%, with one additional malignant diagnosis (0.26%). The adenoma miss rate was 3.6%. On multivariate analysis, a polyp ≥10mm was the only high-risk indication associated with additional ADR at colonoscopy (odds ratio [OR] 3.68, 95% confidence interval [CI]:1.51-3.65, p<0.001), in addition to male gender (OR 2.36, 95% CI:1.46-3.83, p<0.001). Predictors of detection of a new adenoma ≥10mm included: villous adenoma (p=0.002), polyp≥10mm (p=0.007) and male gender (p=0.039). Presence of any conversion criteria was associated with the detection of any proximal adenoma (p<0.001) and adenoma ≥10mm (p=0.031). Male gender, ≥10mm polyps and villous-preponderant histology at FS were predictors of <10mm and ≥10mm adenomas at colonoscopy. Further data are required to assess the role for gender-based stratification of conversion criteria. This article is protected by copyright. All rights reserved. This article is protected by copyright. All rights reserved.

Geological-geotechnical studies for siting the Superconducting Super Collider in Illinois: results of the 1986 test drilling program. Environmental geology notes

International Nuclear Information System (INIS)

Curry, B.B.; Graese, A.M.; Hasek, M.J.; Vaiden, R.C.; Bauer, R.A.

1988-01-01

From 1984 through 1986, geologists from the Illinois State Geological Survey (ISGS) conducted a thorough field investigation in northeastern Illinois to determine whether the surface and subsurface geology would be suitable for constructing the U.S. Department of Energy's 20-TeV (trillion electron volt) particle accelerator - the Superconducting Super Collider (SSC). The third and final stage of test drilling in 1986 concentrated on a specific corridor proposed for the racetrack-shaped SSC that would circle deep below the surface of Kane, Kendall, and Du Page Counties. The main objective was to verify that bedrock lying under the region satisified the site criteria for construction of a 10-foot-diameter tunnel to hold the particle accelerator and the superconducting magnets, large chambers to house the laboratories and computers for conducting and recording experiments, and shafts to provide access to the subterranean facilities. Thirteen test holes, ISGS S-18 through S-30, were drilled to depths ranging from 398.2 to 646.6 feet. The field team recovered 5675 feet of bedrock core and 212 samples of glacial drift (sand, clay, gravel) for laboratory analyses and recorded on-site data that establish the thickness, distribution, lithology (composition), and other properties of the rocks lying under the study area

Information needs for characterization of high-level waste repository sites in six geologic media. Volume 1. Main report

International Nuclear Information System (INIS)

1985-05-01

Evaluation of the geologic isolation of radioactive materials from the biosphere requires an intimate knowledge of site geologic conditions, which is gained through precharacterization and site characterization studies. This report presents the results of an intensive literature review, analysis and compilation to delineate the information needs, applicable techniques and evaluation criteria for programs to adequately characterize a site in six geologic media. These media, in order of presentation, are: granite, shale, basalt, tuff, bedded salt and dome salt. Guidelines are presented to assess the efficacy (application, effectiveness, and resolution) of currently used exploratory and testing techniques for precharacterization or characterization of a site. These guidelines include the reliability, accuracy and resolution of techniques deemed acceptable, as well as cost estimates of various field and laboratory techniques used to obtain the necessary information. Guidelines presented do not assess the relative suitability of media. 351 refs., 10 figs., 31 tabs

Information needs for characterization of high-level waste repository sites in six geologic media. Volume 1. Main report

Energy Technology Data Exchange (ETDEWEB)

NONE

1985-05-01

Evaluation of the geologic isolation of radioactive materials from the biosphere requires an intimate knowledge of site geologic conditions, which is gained through precharacterization and site characterization studies. This report presents the results of an intensive literature review, analysis and compilation to delineate the information needs, applicable techniques and evaluation criteria for programs to adequately characterize a site in six geologic media. These media, in order of presentation, are: granite, shale, basalt, tuff, bedded salt and dome salt. Guidelines are presented to assess the efficacy (application, effectiveness, and resolution) of currently used exploratory and testing techniques for precharacterization or characterization of a site. These guidelines include the reliability, accuracy and resolution of techniques deemed acceptable, as well as cost estimates of various field and laboratory techniques used to obtain the necessary information. Guidelines presented do not assess the relative suitability of media. 351 refs., 10 figs., 31 tabs.

Viewpoint of defining the groundwater chemistry for the performance assessment on geological disposal of high level radioactive waste

International Nuclear Information System (INIS)

Sasamoto, Hiroshi; Yui, Mikazu

2000-01-01

This report presents the viewpoint of defining the groundwater chemistry for performance assessment of the second progress report for research and development on geological disposal. Based on the results of statistical analysis (binary scatter plots) of the measured data in addition to the consideration of the first progress report, we defined the five hypothetically modeled groundwaters considering the general geological conditions and importance for performance assessment. In order to evaluate the priority of groundwater chemistries, we have analyzed the above five hypothetical groundwaters by considering the results of multivariate statistical analyses, data reliability, evidence for geochemical controls on groundwater chemistry and exclusion criteria for potential repository sites in Japan. As a result, the fresh reducing high pH (FRHP) type groundwater has been selected for the Reference Case analysis, and the saline reducing high pH (SRHP) type groundwater has been selected for the Alternative Geological Environmental Case analysis, respectively. (author)

A fully automated primary screening system for the discovery of therapeutic antibodies directly from B cells.

Science.gov (United States)

Tickle, Simon; Howells, Louise; O'Dowd, Victoria; Starkie, Dale; Whale, Kevin; Saunders, Mark; Lee, David; Lightwood, Daniel

2015-04-01

For a therapeutic antibody to succeed, it must meet a range of potency, stability, and specificity criteria. Many of these characteristics are conferred by the amino acid sequence of the heavy and light chain variable regions and, for this reason, can be screened for during antibody selection. However, it is important to consider that antibodies satisfying all these criteria may be of low frequency in an immunized animal; for this reason, it is essential to have a mechanism that allows for efficient sampling of the immune repertoire. UCB's core antibody discovery platform combines high-throughput B cell culture screening and the identification and isolation of single, antigen-specific IgG-secreting B cells through a proprietary technique called the "fluorescent foci" method. Using state-of-the-art automation to facilitate primary screening, extremely efficient interrogation of the natural antibody repertoire is made possible; more than 1 billion immune B cells can now be screened to provide a useful starting point from which to identify the rare therapeutic antibody. This article will describe the design, construction, and commissioning of a bespoke automated screening platform and two examples of how it was used to screen for antibodies against two targets. © 2014 Society for Laboratory Automation and Screening.

Preclosure seismic design methodology for a geologic repository at Yucca Mountain. Topical report YMP/TR-003-NP

International Nuclear Information System (INIS)

1996-10-01

This topical report describes the methodology and criteria that the U.S. Department of Energy (DOE) proposes to use for preclosure seismic design of structures, systems, and components (SSCs) of the proposed geologic repository operations area that are important to safety. Title 10 of the Code of Federal Regulations, Part 60 (10 CFR 60), Disposal of High-Level Radioactive Wastes in Geologic Repositories, states that for a license to be issued for operation of a high-level waste repository, the U.S. Nuclear Regulatory Commission (NRC) must find that the facility will not constitute an unreasonable risk to the health and safety of the public. Section 60.131 (b)(1) requires that SSCs important to safety be designed so that natural phenomena and environmental conditions anticipated at the geologic repository operations area will not interfere with necessary safety functions. Among the natural phenomena specifically identified in the regulation as requiring safety consideration are the hazards of ground shaking and fault displacement due to earthquakes

AEGIS geologic simulation model

International Nuclear Information System (INIS)

Foley, M.G.

1982-01-01

The Geologic Simulation Model (GSM) is used by the AEGIS (Assessment of Effectiveness of Geologic Isolation Systems) program at the Pacific Northwest Laboratory to simulate the dynamic geology and hydrology of a geologic nuclear waste repository site over a million-year period following repository closure. The GSM helps to organize geologic/hydrologic data; to focus attention on active natural processes by requiring their simulation; and, through interactive simulation and calibration, to reduce subjective evaluations of the geologic system. During each computer run, the GSM produces a million-year geologic history that is possible for the region and the repository site. In addition, the GSM records in permanent history files everything that occurred during that time span. Statistical analyses of data in the history files of several hundred simulations are used to classify typical evolutionary paths, to establish the probabilities associated with deviations from the typical paths, and to determine which types of perturbations of the geologic/hydrologic system, if any, are most likely to occur. These simulations will be evaluated by geologists familiar with the repository region to determine validity of the results. Perturbed systems that are determined to be the most realistic, within whatever probability limits are established, will be used for the analyses that involve radionuclide transport and dose models. The GSM is designed to be continuously refined and updated. Simulation models are site specific, and, although the submodels may have limited general applicability, the input data equirements necessitate detailed characterization of each site before application

Geologic disposal of spent nuclear fuel and nuclear waste: Ethical and technical bases for standards and criteria to protect public health

International Nuclear Information System (INIS)

Pigford, T.H.

1999-01-01

The proposed geologic repositories being designed in the US and in other countries that have nuclear power plants need well-defined goals and criteria to protect public health. The criteria must be stringent enough to build confidence in the adequacy of public health protection in the face of legal and political challenges. Yet, there are emerging pressures for relaxation of traditional approaches to protect public health when applied to buried radioactive waste. To build acceptance by the scientific community and the public, both the benefits and consequences of proposed relaxed standards must be dealt with openly and understandably. Arguments over safety standards center on six key issues. (1) For how long must public health protection be assured? Should protection be based on calculated radiation doses to people living for many tens of thousands of years in the future, until peak values of calculated radiation have appeared, or should the protection period be limited to a few thousand years? (2) Whom to protect? Should protection be based on protecting the critical group of future people who unknowingly eat food and drink water contaminated by released radioactivity or should it be based on limiting the average exposure, averaged over all persons projected to live within 'the vicinity' of the repository site? (3) How much radiation exposure should be allowed? Should future people be protected to the same level of radiation exposure as now required for licensed nuclear facilities, or should greater exposures be allowed because future people might be better protected by medical breakthroughs or by their taking remedial action to detect and clean up radioactivity that reaches the environment? (4) Can future people be excluded from using contaminated water drawn from near the site? Should protection of future people be based on doses calculated for ground water extracted from present farming wells, where distance and dilution resulted in lower calculated contaminant

Regulating the long-term safety of geological disposal of radioactive waste: practical issues and challenges

International Nuclear Information System (INIS)

2008-01-01

Regulating the long-term safety of geological disposal of radioactive waste is a key part of making progress on the radioactive waste management issue. A survey of member countries has shown that differences exist both in the protection criteria being applied and in the methods for demonstrating compliance, reflecting historical and cultural differences between countries which in turn result in a diversity of decision-making approaches and frameworks. At the same time, however, these differences in criteria are unlikely to result in significant differences in long-term protection, as all the standards being proposed are well below levels at which actual effects of radiological exposure can be observed and a range of complementary requirements is foreseen. In order to enable experts from a wide range of backgrounds to debate the various aspects of these findings, the NEA organised an international workshop in November 2006 in Paris, France. Discussions focused on diversity in regulatory processes; the basis and tools for assuring long-term protection; ethical responsibilities of one generation to later generations and how these can be discharged; and adapting regulatory processes to the long time frames involved in implementing geological disposal. These proceedings include a summary of the viewpoints expressed as well as the 22 papers presented at the workshop. (author)

The World Health Organization Adult Attention-Deficit/Hyperactivity Disorder Self-Report Screening Scale for DSM-5.

Science.gov (United States)

Ustun, Berk; Adler, Lenard A; Rudin, Cynthia; Faraone, Stephen V; Spencer, Thomas J; Berglund, Patricia; Gruber, Michael J; Kessler, Ronald C

2017-05-01

Recognition that adult attention-deficit/hyperactivity disorder (ADHD) is common, seriously impairing, and usually undiagnosed has led to the development of adult ADHD screening scales for use in community, workplace, and primary care settings. However, these scales are all calibrated to DSM-IV criteria, which are narrower than the recently developed DSM-5 criteria. To update for DSM-5 criteria and improve the operating characteristics of the widely used World Health Organization Adult ADHD Self-Report Scale (ASRS) for screening. Probability subsamples of participants in 2 general population surveys (2001-2003 household survey [n = 119] and 2004-2005 managed care subscriber survey [n = 218]) who completed the full 29-question self-report ASRS, with both subsamples over-sampling ASRS-screened positives, were blindly administered a semistructured research diagnostic interview for DSM-5 adult ADHD. In 2016, the Risk-Calibrated Supersparse Linear Integer Model, a novel machine-learning algorithm designed to create screening scales with optimal integer weights and limited numbers of screening questions, was applied to the pooled data to create a DSM-5 version of the ASRS screening scale. The accuracy of the new scale was then confirmed in an independent 2011-2012 clinical sample of patients seeking evaluation at the New York University Langone Medical Center Adult ADHD Program (NYU Langone) and 2015-2016 primary care controls (n = 300). Data analysis was conducted from April 4, 2016, to September 22, 2016. The sensitivity, specificity, area under the curve (AUC), and positive predictive value (PPV) of the revised ASRS. Of the total 637 participants, 44 (37.0%) household survey respondents, 51 (23.4%) managed care respondents, and 173 (57.7%) NYU Langone respondents met DSM-5 criteria for adult ADHD in the semistructured diagnostic interview. Of the respondents who met DSM-5 criteria for adult ADHD, 123 were male (45.9%); mean (SD) age was 33.1 (11.4) years

The World Health Organization Adult Attention-Deficit/Hyperactivity Disorder Self-Report Screening Scale for DSM-5

Science.gov (United States)

Ustun, Berk; Adler, Lenard A.; Rudin, Cynthia; Faraone, Stephen V.; Spencer, Thomas J.; Berglund, Patricia; Gruber, Michael J.

2017-01-01

Importance Recognition that adult attention-deficit/hyperactivity disorder (ADHD) is common, seriously impairing, and usually undiagnosed has led to the development of adult ADHD screening scales for use in community, workplace, and primary care settings. However, these scales are all calibrated to DSM-IV criteria, which are narrower than the recently developed DSM-5 criteria. Objectives To update for DSM-5 criteria and improve the operating characteristics of the widely used World Health Organization Adult ADHD Self-Report Scale (ASRS) for screening. Design, Setting, and Participants Probability subsamples of participants in 2 general population surveys (2001-2003 household survey [n = 119] and 2004-2005 managed care subscriber survey [n = 218]) who completed the full 29-question self-report ASRS, with both subsamples over-sampling ASRS-screened positives, were blindly administered a semistructured research diagnostic interview for DSM-5 adult ADHD. In 2016, the Risk-Calibrated Supersparse Linear Integer Model, a novel machine-learning algorithm designed to create screening scales with optimal integer weights and limited numbers of screening questions, was applied to the pooled data to create a DSM-5 version of the ASRS screening scale. The accuracy of the new scale was then confirmed in an independent 2011-2012 clinical sample of patients seeking evaluation at the New York University Langone Medical Center Adult ADHD Program (NYU Langone) and 2015-2016 primary care controls (n = 300). Data analysis was conducted from April 4, 2016, to September 22, 2016. Main Outcomes and Measures The sensitivity, specificity, area under the curve (AUC), and positive predictive value (PPV) of the revised ASRS. Results Of the total 637 participants, 44 (37.0%) household survey respondents, 51 (23.4%) managed care respondents, and 173 (57.7%) NYU Langone respondents met DSM-5 criteria for adult ADHD in the semistructured diagnostic interview. Of the respondents who met

77 FR 15101 - Results From Inert Ingredient Test Orders Issued Under EPA's Endocrine Disruptor Screening...

Science.gov (United States)

2012-03-14

... the selection criteria for endocrine testing under the Safe Drinking Water Act (SDWA). EPA has no...) because the chemicals meet the selection criteria. EPA has no plans to issue further test orders for the... Screening Program (EDSP) and the Federal Food, Drug, and Cosmetic Act (FFDCA). In response to the test...

Screening criteria for siting waste management facilities: Regional Management Plan

International Nuclear Information System (INIS)

1986-01-01

The Midwest Interstate Low-Level Radioactive Waste Commission (Midwest Compact) seeks to define and place into operation a system for low-level waste management that will protect the public health and safety and the environment from the time the waste leaves its point of origin. Once the system is defined it will be necessary to find suitable sites for the components of that waste management system. The procedure for siting waste management facilities that have been chosen by the compact is one in which a host state is chosen for each facility. The host state is then given the freedom to select the site. Sites will be needed of low-level waste disposal facilities. Depending on the nature of the waste management system chosen by the host state, sites may also be needed for regional waste treatment facilities, such as compactors or incinerators. This report provides example criteria for use in selecting sites for low-level radioactive waste treatment and disposal facilities. 14 refs

Impact of the dynamic and static component of the sport practised for electrocardiogram analysis in screening athletes.

Science.gov (United States)

Maillot, N; Guenancia, C; Yameogo, N V; Gudjoncik, A; Garnier, F; Lorgis, L; Chagué, F; Cottin, Y

2018-02-01

To interpret the electrocardiogram (ECG) of athletes, the recommendations of the ESC and the Seattle criteria define type 1 peculiarities, those induced by training, and type 2, those not induced by training, to rule out cardiomyopathy. The specificity of the screening was improved by Sheikh who defined "Refined Criteria," which includes a group of intermediate peculiarities. The aim of our study was to investigate the influence of static and dynamic components on the prevalence of different types of abnormalities. The ECGs of 1030 athletes performed during preparticipation screening were interpreted using these three classifications. Our work revealed 62/16%, 69/13%, and 71/7% of type 1 peculiarities and type 2 abnormalities for the ESC, Seattle, and Refined Criteria algorithms, respectively(P<.001). For type 2 abnormalities, three independent factors were found for the ESC and Seattle criteria: age, Afro-Caribbean origin, and the dynamic component with, for the latter, an OR[95% CI] of 2.35[1.28-4.33] (P=.006) and 1.90[1.03-3.51] (P=.041), respectively. In contrast, only the Afro-Caribbean origin was associated with type 2 abnormalities using the Refined Criteria: OR[95% CI] 2.67[1.60-4.46] (P<.0001). The Refined Criteria classified more athletes in the type 1 category and fewer in the type 2 category compared with the ESC and Seattle algorithms. Contrary to previous studies, a high dynamic component was not associated with type 2 abnormalities when the Refined Criteria were used; only the Afro-Caribbean origin remained associated. Further research is necessary to better understand adaptations with regard to duration and thus improve the modern criteria for ECG screening in athletes. © 2017 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Attitudes toward newborn screening for cytomegalovirus infection.

Science.gov (United States)

Din, Erica S; Brown, Cedric J; Grosse, Scott D; Wang, Chengbin; Bialek, Stephanie R; Ross, Danielle S; Cannon, Michael J

2011-12-01

Newborns are not routinely screened for cytomegalovirus (CMV), the leading infectious cause of developmental disability. Congenital CMV satisfies a number of criteria for inclusion in newborn screening, and screening potentially offers benefits. Screening could also introduce harms such as anxiety and unnecessary costs for the families of the substantial proportion of CMV-infected children who never develop CMV-related disabilities. Our objective was to assess attitudes toward newborn screening for CMV. We analyzed responses to 5 statements about CMV and newborn screening from 3922 participants in the 2009 HealthStyles survey, a national mail survey designed to include a group similar to the US population with respect to gender, age, race/ethnicity, income, and household size. Two-step cluster analysis was performed to identify clusters of parental attitudes. The majority of respondents strongly or somewhat agreed that they would want to have their newborn tested for CMV even if it was not performed routinely (84%), they had to pay $20 (87%), or CMV-related problems never developed (84%). Nearly half (47%) of them "would worry that the CMV test would lead to unneeded doctor visits and expenses," and 32% "think CMV problems are too rare to worry about." Three clusters of parent respondents were identified on the basis of their attitudes toward CMV screening: "strongly in favor" (31%), "moderately in favor" (49%), and "weakly opposed" (20%). Among most parents, costs, worry, and anxiety associated with newborn screening for CMV would be acceptable. Although attitudes were generally favorable, a minority of the parents were weakly opposed to newborn screening for CMV.

Validation of The 3-Question Headache Screen in The Diagnosis of ...

African Journals Online (AJOL)

diagnosed and undertreated. A rapid diagnostic method is desirable so that treatment can be initiated early. We compared the 3-question headache screen with the International Headache Society (IHS) criteria in the diagnosis of migraine among ...

WE-D-207-03: CT Protocols for Screening and the ACR Designated Lung Screening Program

International Nuclear Information System (INIS)

McNitt-Gray, M.

2015-01-01

In the United States, Lung Cancer is responsible for more cancer deaths than the next four cancers combined. In addition, the 5 year survival rate for lung cancer patients has not improved over the past 40 to 50 years. To combat this deadly disease, in 2002 the National Cancer Institute launched a very large Randomized Control Trial called the National Lung Screening Trial (NLST). This trial would randomize subjects who had substantial risk of lung cancer (due to age and smoking history) into either a Chest X-ray arm or a low dose CT arm. In November 2010, the National Cancer Institute announced that the NLST had demonstrated 20% fewer lung cancer deaths among those who were screened with low-dose CT than with chest X-ray. In December 2013, the US Preventive Services Task Force recommended the use of Lung Cancer Screening using low dose CT and a little over a year later (Feb. 2015), CMS announced that Medicare would also cover Lung Cancer Screening using low dose CT. Thus private and public insurers are required to provide Lung Cancer Screening programs using CT to the appropriate population(s). The purpose of this Symposium is to inform medical physicists and prepare them to support the implementation of Lung Screening programs. This Symposium will focus on the clinical aspects of lung cancer screening, requirements of a screening registry for systematically capturing and tracking screening patients and results (such as required Medicare data elements) as well as the role of the medical physicist in screening programs, including the development of low dose CT screening protocols. Learning Objectives: To understand the clinical basis and clinical components of a lung cancer screening program, including eligibility criteria and other requirements. To understand the data collection requirements, workflow, and informatics infrastructure needed to support the tracking and reporting components of a screening program. To understand the role of the medical physicist in

Evaluation of Five Sedimentary Rocks Other Than Salt for Geologic Repository Siting Purposes

Energy Technology Data Exchange (ETDEWEB)

Croff, A.G.; Lomenick, T.F.; Lowrie, R.S.; Stow, S.H.

2003-11-15

The US Department of Energy (DOE), in order to increase the diversity of rock types under consideration by the geologic disposal program, initiated the Sedimary ROck Program (SERP), whose immediate objectiv eis to evaluate five types of secimdnary rock - sandstone, chalk, carbonate rocks (limestone and dolostone), anhydrock, and shale - to determine the potential for siting a geologic repository. The evaluation of these five rock types, together with the ongoing salt studies, effectively results in the consideration of all types of relatively impermeable sedimentary rock for repository purposes. The results of this evaluation are expressed in terms of a ranking of the five rock types with respect to their potential to serve as a geologic repository host rock. This comparative evaluation was conducted on a non-site-specific basis, by use of generic information together with rock evaluation criteria (RECs) derived from the DOE siting guidelines for geologic repositories (CFR 1984). An information base relevant to rock evaluation using these RECs was developed in hydrology, geochemistry, rock characteristics (rock occurrences, thermal response, rock mechanics), natural resources, and rock dissolution. Evaluation against postclosure and preclosure RECs yielded a ranking of the five subject rocks with respect to their potential as repository host rocks. Shale was determined to be the most preferred of the five rock types, with sandstone a distant second, the carbonate rocks and anhydrock a more distant third, and chalk a relatively close fourth.

Evaluation of Five Sedimentary Rocks Other Than Salt for Geologic Repository Siting Purposes

International Nuclear Information System (INIS)

Croff, A.G.; Lomenick, T.F.; Lowrie, R.S.; Stow, S.H.

2003-01-01

The US Department of Energy (DOE), in order to increase the diversity of rock types under consideration by the geologic disposal program, initiated the Sedimary ROck Program (SERP), whose immediate objectiv eis to evaluate five types of secimdnary rock - sandstone, chalk, carbonate rocks (limestone and dolostone), anhydrock, and shale - to determine the potential for siting a geologic repository. The evaluation of these five rock types, together with the ongoing salt studies, effectively results in the consideration of all types of relatively impermeable sedimentary rock for repository purposes. The results of this evaluation are expressed in terms of a ranking of the five rock types with respect to their potential to serve as a geologic repository host rock. This comparative evaluation was conducted on a non-site-specific basis, by use of generic information together with rock evaluation criteria (RECs) derived from the DOE siting guidelines for geologic repositories (CFR 1984). An information base relevant to rock evaluation using these RECs was developed in hydrology, geochemistry, rock characteristics (rock occurrences, thermal response, rock mechanics), natural resources, and rock dissolution. Evaluation against postclosure and preclosure RECs yielded a ranking of the five subject rocks with respect to their potential as repository host rocks. Shale was determined to be the most preferred of the five rock types, with sandstone a distant second, the carbonate rocks and anhydrock a more distant third, and chalk a relatively close fourth.

Assessment of heterogeneous geological environment at Tono. Japanese fiscal year 2004 (Contract research)

International Nuclear Information System (INIS)

Toida, Masaru; Suyama, Yasuhiro; Mori, Takayuki; Inaba, Takeshi; Sasakura, Takeshi; Atsumi, Hiroyuki; Masumoto, Kazuhiko; Kobayashi, Ichizo; Iwano, Keita; Furuichi, Mitsuaki; Ogata, Nobuhisa

2007-09-01

'Geoscientific research' at the Tono Area is developing site investigation, characterization and assessment techniques for understanding of geological environment. Their important goals are to establish a methodology for analyzing uncertainties in heterogeneous geological environment and to develop investigation technique for efficiently reducing the uncertainties. The current study proposes a new approach where all the possible options in the models and data-sets, which cannot be excluded in the light of the evidences available, are identified. This approach enables uncertainties associated with the understanding at a given stage of the site characterization to be made explicitly using an uncertainty analysis technique based on Fuzzy geostatics. This approach supports the design of the following investigation stage and reduces the uncertainties efficiently. In FY H16 the technique has been tested through geological modelling and groundwater analyses with Tono Area case based on current knowledge, to demonstrate its applicability and to compile the knowledge/information required to describe the H17 report. This report can be summarized as follows: 1) The knowledge/information required to describe the heterogeneous characteristics was compiled and connected to uncertainties associated with the characterization of a geological environment using a synthesis diagram. 2) Methodologies for assignment and screening of parameters were developed by using Evidential Support Logic (ESL). 3) Applicability of the technique could be confirmed with Tono Area case. 4) This report proposed a new methodology that integrates the technique into JAEA ordinary technique to good advantage in the geoscientific research project. (author)

Global Journal of Geological Sciences: Editorial Policies

African Journals Online (AJOL)

Focus and Scope. Global Journal of Geological Sciences is aimed at promoting research in all areas of geological Sciences including Petrology, Mineralogy, geophysics, hydrogeology, Engineering geology, Petroleum geology, Palaeontology, environmental geology, Economic geology, etc.

Hepatitis C screening trends in a large integrated health system.

Science.gov (United States)

Linas, Benjamin P; Hu, Haihong; Barter, Devra M; Horberg, Michael

2014-05-01

As new hepatitis C virus (HCV) therapies emerge, only 1%-12% of individuals are screened in the US for HCV infection. Presently, HCV screening trends are unknown. We utilized the Kaiser Permanente Mid-Atlantic States' (KPMAS) data repository to investigate HCV antibody screening between January 1, 2003 and December 31, 2012. We identified the proportion screened for HCV and 5-year cumulative incidence of screening, the screening positivity rate, the provider types performing HCV screening, patient-level factors associated with being screened, and trends in screening over time. There were 444,594 patients who met the inclusion criteria. Overall, 15.8% of the cohort was ever screened for HCV. Adult primary care and obstetrics and gynecology providers performed 75.9% of all screening. The overall test positivity rate was 3.8%. Screening was more frequent in younger age groups (P <.0001) and those with a documented history of illicit drug use (P <.0001). Patients with missing drug use history (46.7%) were least likely to be screened (P <.0001). While the rate of HCV screening increased in the later years of the study among those enrolled in KPMAS 2009-2012, only 11.8% were screened by the end of follow-up. Screening for HCV is increasing but remains incomplete. Targeting screening to those with a history of injection drug will not likely expand screening, as nearly half of patients have no documented drug use history. Routine screening is likely the most effective approach to expand HCV screening. Copyright © 2014. Published by Elsevier Inc.

Formation-evolution model of uranium-productive basin and its recognition criteria

Energy Technology Data Exchange (ETDEWEB)

Zuyi, Chen; Ziying, Li [Beijing Research Inst. of Uranium Geology, Beijing (China); Weixun, Zhou; Taiyang, Guan [East China Inst. of Technology, Fuzhou (China)

2004-11-15

Based on geologic-tectonic setting and dynamic evolution of important U-productive basins both at home and abroad, authors distinguish six type of U-productive basins, and nominate each type by typical representative of this type, namely Chu-Sarysu and Syr-Darya type, Central Kyzylkum type, Zaural and West-Siberia type, Zabaikal type, Bohemia type, and South Texas type. The formation-evolution model of each type of U-productive basin has been established and recognition criteria have been proposed. Finially, the difference between each type U-productive basin is discussed and some assumption on prospecting for U-productive basins is proposed. (authors)

Formation-evolution model of uranium-productive basin and its recognition criteria

International Nuclear Information System (INIS)

Chen Zuyi; Li Ziying; Zhou Weixun; Guan Taiyang

2004-11-01

Based on geologic-tectonic setting and dynamic evolution of important U-productive basins both at home and abroad, authors distinguish six type of U-productive basins, and nominate each type by typical representative of this type, namely Chu-Sarysu and Syr-Darya type, Central Kyzylkum type, Zaural and West-Siberia type, Zabaikal type, Bohemia type, and South Texas type. The formation-evolution model of each type of U-productive basin has been established and recognition criteria have been proposed. Finially, the difference between each type U-productive basin is discussed and some assumption on prospecting for U-productive basins is proposed. (authors)

Assessment of five different guideline indication criteria for spirometry, including modified GOLD criteria, in order to detect COPD: data from 5,315 subjects in the PLATINO study.

Science.gov (United States)

Luize, Ana P; Menezes, Ana Maria B; Perez-Padilla, Rogelio; Muiño, Adriana; López, Maria Victorina; Valdivia, Gonzalo; Lisboa, Carmem; Montes de Oca, Maria; Tálamo, Carlos; Celli, Bartolomé; Nascimento, Oliver A; Gazzotti, Mariana R; Jardim, José R

2014-10-30

Spirometry is the gold standard for diagnosing chronic obstructive pulmonary disease (COPD). Although there are a number of different guideline criteria for deciding who should be selected for spirometric screening, to date it is not known which criteria are the best based on sensitivity and specificity. Firstly, to evaluate the proportion of subjects in the PLATINO Study that would be recommended for spirometry testing according to Global initiative for Obstructive Lung Disease (GOLD)-modified, American College of Chest Physicians (ACCP), National Lung Health Education Program (NLHEP), GOLD and American Thoracic Society/European Respiratory Society (ATS/ERS) criteria. Secondly, we aimed to compare the sensitivity, specificity, and positive predictive and negative predictive values, of these five different criteria. Data from the PLATINO study included information on respiratory symptoms, smoking and previous spirometry testing. The GOLD-modified spirometry indication criteria are based on three positive answers out of five questions: the presence of cough, phlegm in the morning, dyspnoea, age over 40 years and smoking status. Data from 5,315 subjects were reviewed. Fewer people had an indication for spirometry (41.3%) according to the GOLD-modified criteria, and more people had an indication for spirometry (80.4%) by the GOLD and ATS/ERS criteria. A low percentage had previously had spirometry performed: GOLD-modified (14.5%); ACCP (13.2%); NLHEP (12.6%); and GOLD and ATS/ERS (12.3%). The GOLD-modified criteria showed the least sensitivity (54.9) and the highest specificity (61.0) for detecting COPD, whereas GOLD and ATS/ERS criteria showed the highest sensitivity (87.9) and the least specificity (20.8). There is a considerable difference in the indication for spirometry according to the five different guideline criteria. The GOLD-modified criteria recruit less people with the greatest sum of sensitivity and specificity.

Mammography screening: A major issue in medicine.

Science.gov (United States)

Autier, Philippe; Boniol, Mathieu

2018-02-01

Breast cancer mortality is declining in most high-income countries. The role of mammography screening in these declines is much debated. Screening impacts cancer mortality through decreasing the incidence of number of advanced cancers with poor prognosis, while therapies and patient management impact cancer mortality through decreasing the fatality of cancers. The effectiveness of cancer screening is the ability of a screening method to curb the incidence of advanced cancers in populations. Methods for evaluating cancer screening effectiveness are based on the monitoring of age-adjusted incidence rates of advanced cancers that should decrease after the introduction of screening. Likewise, cancer-specific mortality rates should decline more rapidly in areas with screening than in areas without or with lower levels of screening but where patient management is similar. These two criteria have provided evidence that screening for colorectal and cervical cancer contributes to decreasing the mortality associated with these two cancers. In contrast, screening for neuroblastoma in children was discontinued in the early 2000s because these two criteria were not met. In addition, overdiagnosis - i.e. the detection of non-progressing occult neuroblastoma that would not have been life-threatening during the subject's lifetime - is a major undesirable consequence of screening. Accumulating epidemiological data show that in populations where mammography screening has been widespread for a long time, there has been no or only a modest decline in the incidence of advanced cancers, including that of de novo metastatic (stage IV) cancers at diagnosis. Moreover, breast cancer mortality reductions are similar in areas with early introduction and high penetration of screening and in areas with late introduction and low penetration of screening. Overdiagnosis is commonplace, representing 20% or more of all breast cancers among women invited to screening and 30-50% of screen

Education for screen use as holistic praxis

Directory of Open Access Journals (Sweden)

Lic. José Antonio Gabelas Barroso

2007-09-01

Full Text Available New generations maintain a very close daily relationship with screens (television, Internet, video consoles and mobile telephones. A lot of their leisure time centres on these means of communication with a double purpose: either for playing or communicating with others. These are the two dimensions (recreational and social that dominate the choice of these types of communication in order to entertain oneself and/or establish relationships with their groups of friends. The trend in the consumption of screens has distanced television from its previous monopoly and has meant that it has to share young people’s leisure time with other advanced technological supports. The health of children and adolescents involves educating them towards a healthy and responsible consumption of all screens, in a balanced way as regards dosis and planning, and with criteria as regards the content that could endanger them and the level of their cognitive development.

Testing some of Benjamin Graham’s Stock Selection Criteria: A Case of the FTSE Bursa Malaysia EMAS Index from Year 2000 to 2009

Directory of Open Access Journals (Sweden)

Desmond Chang

2011-01-01

Full Text Available Benjamin Graham, also known as the “father of value investing” proposed that investment in the stock exchange can be a safe endeavor while receiving gains that outperform the market if the investor makes carefully thought out purchases. This study aims to determine if the use of some of Benjamin Graham’s stock selection criteria is able to generate returns that are significantly greater than the returns in the stock exchange of Malaysia, particularly, the comprehensive FTSE Bursa Malaysia EMAS Index. This study collected secondary data regarding fundamentals of companies listed in the FTSE Bursa Malaysia EMAS Index from the year 2000 to 2009. Five criteria were set up in this research based on one or a combination of price-to-earnings ratio, price-to-book value, current ratio and dividend yield. The listed companies were screened using those criteria. An equally weighted portfolio was created using the screened companies and their one-year and two-year returns calculated. The returns were compared to the market return. Hypotheses of this research were tested using t-test statistic to determine the significance of the data. This research found that most of the screening criteria used generated returns that were higher than the market return in almost every year they were tested in. Benjamin Graham’s stock selection criteria although have been conceived over 80 years ago is still applicable today in the Malaysian market. Further research can be conducted with different criteria with varying holding periods and in different markets.

Assessment of effectiveness of geologic isolation systems: the AEGIS geologic simulation model

International Nuclear Information System (INIS)

Foley, M.G.; Petrie, G.M.

1981-02-01

Assessment of the post-closure performance of a nuclear waste repository has two basic components: the identification and analysis of potentially disruptive sequences and the pattern of geologic events and processes causing each sequence, and the identification and analysis of the environmental consequences of radionuclide transport and interactions subsequent to disruption of a repository. The AEGIS Scenario Analysis Task is charged with identifying and analyzing potenially disruptive sequences of geologic events and processes. The Geologic Simulation Model (GSM) was developed to evaluate the geologic/hydrologic system surrounding an underground repository, and describe the phenomena that alone, or in concert, could perturb the system and possibly cause a loss of repository integrity. The AEGIS approach is described in this report. It uses an integrated series of models for repository performance analysis; the GSM for a low-resolution, long-term, comprehensive evaluation of the geologic/hydrologic system, followed by more detailed hydrogeologic, radionuclide transport, and dose models to more accurately assess the consequences of disruptive sequences selected from the GSM analyses. This approach is felt to be more cost-effective than an integrated one because the GSM can be used to estimate the likelihoods of different potentially disruptive future evolutionary developments within the geologic/hydrologic system. The more costly consequence models can then be focused on a few disruptive sequences chosen for their representativeness and effective probabilities

Geological studies in Alaska by the U.S. Geological Survey, 1999

Science.gov (United States)

Gough, Larry P.; Wilson, Frederic H.

2001-01-01

The collection of nine papers that follow continue the series of U.S. Geological Survey (USGS) investigative reports in Alaska under the broad umbrella of the geologic sciences. The series presents new and sometimes preliminary findings that are of interest to earth scientists in academia, government, and industry; to land and resource managers; and to the general public. Reports presented in Geologic Studies in Alaska cover a broad spectrum of topics from various parts of the State (fig. 1), serving to emphasize the diversity of USGS efforts to meet the Nation's needs for earth-science information in Alaska.

INDUSTRIAL/MILITARY ACTIVITY-INITIATED ACCIDENT SCREENING ANALYSIS

Energy Technology Data Exchange (ETDEWEB)

D.A. Kalinich

1999-09-27

Impacts due to nearby installations and operations were determined in the Preliminary MGDS Hazards Analysis (CRWMS M&O 1996) to be potentially applicable to the proposed repository at Yucca Mountain. This determination was conservatively based on limited knowledge of the potential activities ongoing on or off the Nevada Test Site (NTS). It is intended that the Industrial/Military Activity-Initiated Accident Screening Analysis provided herein will meet the requirements of the ''Standard Review Plan for the Review of Safety Analysis Reports for Nuclear Power Plants'' (NRC 1987) in establishing whether this external event can be screened from further consideration or must be included as a design basis event (DBE) in the development of accident scenarios for the Monitored Geologic Repository (MGR). This analysis only considers issues related to preclosure radiological safety. Issues important to waste isolation as related to impact from nearby installations will be covered in the MGR performance assessment.

Regional prognosis criteria for the sandstone type uranium deposits in interlayer oxidation zone and their application in the east of Junggar basin, Xinjiang

International Nuclear Information System (INIS)

Han Deren; Bai Fengzhou; Lin Shuangxing

1995-01-01

Regional prognosis is of a very important role in the exploration work of the sandstone type uranium deposits of interlayer oxidation zone. This paper presents regional prognosis criteria on the basis of the authors' research in combination with the geological prediction in the east of Junggar Basin, Xinjiang (1:200000) which was jointly carried out with the Red Hill Geological Complex of the National Mineral Resources Commission of Uzbekistan Republic. It is advantageous to the exploration work of the sandstone type uranium deposits of interlayer oxidation zone in Meso-Cenozoic basins of China

Acquisition system environmental effects study. [for capillary-screen propellant retention devices

Science.gov (United States)

1975-01-01

The effects of vibration, warm gas exposure, and feed system startup/shutdown fluid dynamics on capillary-screen propellant retention capabilities are quantified. The existing technology is extended to the point where quantitative conlusions in terms of design criteria may be drawn.

Safety indicators in different time frames for the safety assessment of underground radioactive waste repositories. First report of the INWAC subgroup on principles and criteria for radioactive waste disposal

International Nuclear Information System (INIS)

1994-10-01

Principles and criteria for the disposal of long lived radioactive waste involve issues which go beyond those normally considered in the basic system of radiation protection. Safety criteria based on radiation risk an dose limitation are commonly accepted as the principal basis for judging the acceptability of radioactive waste repositories. However, the long time-scales of interest mean that risks or doses to future individuals cannot be predicted with any certainty as they depend, amongst other things, on assumptions made about the integrity of the waste matrix, the man-made barriers, the geology, the dispersion of groundwater, etc. and future biospheric conditions and human lifestyles. This document discusses various safety indicators and their applicability in the context of the future time-scales which have to be considered in safety assessments of deep geologic repositories. Quantitative assessment are based on numerical estimates of consequences (e.g. risk or dose) and the assessment is made against numerical criteria. Qualitative assessments are based on estimates of hazard potential which are not exact or absolute and the assessment is made against criteria which may not be numerically defined. Examples of such criteria are the convenient reference values provided by levels of radionuclides in the natural environment. Refs, figs and tabs

Geologic influence on indoor radon concentrations and gamma radiation levels in Norwegian dwellings

Energy Technology Data Exchange (ETDEWEB)

Sundal, Aud Venche

2003-09-01

dose rates are measured in the areas covered by nearly impermeable silt and clay deposits. Indoor gamma dose rates as high as 620 nGy/h are obtained in the areas of exposed carbonatites, primarily due to enhanced thorium concentrations in these rock types. The observed correlations between geological factors and indoor radon concentrations in Norway indicate that geological information is a useful tool in radon risk analysis. Resources can be concentrated to regions of high geologic radon potential when screening programs are planned, and efficient follow-up surveys can be established based on geological data in combination with radon measurements in a representative sample of the building stock. The observed contrasts in radon risk potential between different types of building grounds also enable the prediction of radon risk in areas which are not currently inhabited. (Author)

Fault plane solutions as related to known geological faults in and near India

Directory of Open Access Journals (Sweden)

N. SRIVASTAVA

1975-05-01

Full Text Available Based on the focal mechanism solutions of newly determined solutions, and other recent workers the correlation between one of the nodal planes and the geological faults has been discussed for three regions namely Kashmir, Central Himalayas and northeast India including Assam. The variability between multiple solutions reported for some earthquakes and the limitations in the choice of the nodal plane from /'-wave solutions have been brought out. It is seen that no standard criteria either on the basis of isoseismals or of aftershocks can be used to distinguish the fault plane from the auxiliary plane. It has been found that in general there is good agreement between one of the nodal planes and the geological faults in Kashmir and the Central Himalayas. In northeast India, the strike directions obtained from the mechanism solutions generally agree with the trends of the main thrusts but the dip direction for shocks originating in the India-Burma border

77 FR 19032 - Geological Survey

Science.gov (United States)

2012-03-29

... DEPARTMENT OF THE INTERIOR Geological Survey Announcement of National Geospatial Advisory Committee Meeting AGENCY: U.S. Geological Survey, Interior. ACTION: Notice of meeting. SUMMARY: The National.... Geological Survey (703-648-6283, [email protected] ). Registrations are due by April 13, 2012. While the...

Geologic studies

International Nuclear Information System (INIS)

Wayland, T.E.; Rood, A.

1983-01-01

The modern Great Divide Basin is the end product of natural forces influenced by the Green River lake system, Laramide tectonism, and intermittent volcanic events. It ranks as one of the most complex structural and stratigtaphic features within the Tertiary basins of Wyoming. Portions of the Great Divide Basin and adjoining areas in Wyoming have been investigated by applying detailed and region exploration methods to known uranium deposits located within the Red Desert portions of the basin. Geologic field investigations conducted by Bendix Field Engineering Corporaton (Bendix) were restricted to reconnaissance observations made during infrequent visits to the project area by various Bendix personnel. Locations of the most comprehensive field activities are shown in Figure II-1. The principal source fo data for geologic studies of the Red Desert project area has been information and materials furnished by industry. Several hundred holes have been drilled by various groups to delineate the uranium deposits. Results from Bendix-drilled holes at selected locations within the project area are summarized in Table II-1. Additional details and gross subsurface characteristics are illustrated in cross sections; pertinent geologic features are illustrated in plan maps. Related details of continental sedimentation that pertain to the Wyoming Basins generally, and the project area specificially, are discussed in subsections of this Geologic Studies section

Fundamentals of Structural Geology

Science.gov (United States)

Pollard, David D.; Fletcher, Raymond C.

2005-09-01

Fundamentals of Structural Geology provides a new framework for the investigation of geological structures by integrating field mapping and mechanical analysis. Assuming a basic knowledge of physical geology, introductory calculus and physics, it emphasizes the observational data, modern mapping technology, principles of continuum mechanics, and the mathematical and computational skills, necessary to quantitatively map, describe, model, and explain deformation in Earth's lithosphere. By starting from the fundamental conservation laws of mass and momentum, the constitutive laws of material behavior, and the kinematic relationships for strain and rate of deformation, the authors demonstrate the relevance of solid and fluid mechanics to structural geology. This book offers a modern quantitative approach to structural geology for advanced students and researchers in structural geology and tectonics. It is supported by a website hosting images from the book, additional colour images, student exercises and MATLAB scripts. Solutions to the exercises are available to instructors. The book integrates field mapping using modern technology with the analysis of structures based on a complete mechanics MATLAB is used to visualize physical fields and analytical results and MATLAB scripts can be downloaded from the website to recreate textbook graphics and enable students to explore their choice of parameters and boundary conditions The supplementary website hosts color images of outcrop photographs used in the text, supplementary color images, and images of textbook figures for classroom presentations The textbook website also includes student exercises designed to instill the fundamental relationships, and to encourage the visualization of the evolution of geological structures; solutions are available to instructors

Sinkhole Susceptibility Analysis for Karapinar/konya via Multi Criteria Decision

Science.gov (United States)

Sarı, F.

2017-11-01

Sinkholes are being a natural hazard which threads economic and human life. Sudden occurrence characteristic of sinkholes make it unable to escape. There are a lot of factor that activate sinkholes such as geology, irrigation, land use and human related factors. In Karapınar, Konya, there are over 200 sinkholes and this count is getting increased in recent years. Especially active agricultural lands, decreasing ground water level, extreme irrigation by 55267 water wells increase the risk factor of Karapınar. Nowadays, considering the economic contribution of Karapınar to Turkey economy in the field of agriculture, solar energy fields and thermal reactor which will be planned in next few years, prediction of sinkholes and searching for preventation ways are being more important issue. In this study, sinkhole susceptibility map via AHP was carried out for Karapınar in Konya. Slope, land use, elevation, geology, water wells, distance to roads and settlements criteria are included to determine susceptibility. The weights are calculated with AHP for each criterion and generated susceptibility map is overlapped with existing sinkholes. Suggestions and results are shared for this study.

SINKHOLE SUSCEPTIBILITY ANALYSIS FOR KARAPINAR/KONYA VIA MULTI CRITERIA DECISION

Directory of Open Access Journals (Sweden)

F. Sarı

2017-11-01

Full Text Available Sinkholes are being a natural hazard which threads economic and human life. Sudden occurrence characteristic of sinkholes make it unable to escape. There are a lot of factor that activate sinkholes such as geology, irrigation, land use and human related factors. In Karapınar, Konya, there are over 200 sinkholes and this count is getting increased in recent years. Especially active agricultural lands, decreasing ground water level, extreme irrigation by 55267 water wells increase the risk factor of Karapınar. Nowadays, considering the economic contribution of Karapınar to Turkey economy in the field of agriculture, solar energy fields and thermal reactor which will be planned in next few years, prediction of sinkholes and searching for preventation ways are being more important issue. In this study, sinkhole susceptibility map via AHP was carried out for Karapınar in Konya. Slope, land use, elevation, geology, water wells, distance to roads and settlements criteria are included to determine susceptibility. The weights are calculated with AHP for each criterion and generated susceptibility map is overlapped with existing sinkholes. Suggestions and results are shared for this study.

A SKOS-based multilingual thesaurus of geological time scale for interopability of online geological maps

NARCIS (Netherlands)

Ma, X.; Carranza, E.J.M.; Wu, C.; Meer, F.D. van der; Liu, G.

2011-01-01

The usefulness of online geological maps is hindered by linguistic barriers. Multilingual geoscience thesauri alleviate linguistic barriers of geological maps. However, the benefits of multilingual geoscience thesauri for online geological maps are less studied. In this regard, we developed a

Database system of geological information for geological evaluation base of NPP sites(I)

International Nuclear Information System (INIS)

Lim, C. B.; Choi, K. R.; Sim, T. M.; No, M. H.; Lee, H. W.; Kim, T. K.; Lim, Y. S.; Hwang, S. K.

2002-01-01

This study aims to provide database system for site suitability analyses of geological information and a processing program for domestic NPP site evaluation. This database system program includes MapObject provided by ESRI and Spread 3.5 OCX, and is coded with Visual Basic language. Major functions of the systematic database program includes vector and raster farmat topographic maps, database design and application, geological symbol plot, the database search for the plotted geological symbol, and so on. The program can also be applied in analyzing not only for lineament trends but also for statistic treatment from geologically site and laboratory information and sources in digital form and algorithm, which is usually used internationally

Walkthrough screening evaluation field guide

International Nuclear Information System (INIS)

Eder, S.J.; Eli, M.W.; Salmon, M.W.

1993-11-01

The US Department of Energy (DOE) has a large inventory of existing facilities. Many of these facilities were not designed and constructed to current natural phenomena hazard (NPH) criteria. The NPH events include earthquakes, extreme winds and tornadoes, and floods. DOE Order 5480.28 establishes policy and requirements for NPH mitigation for DOE facilities. DOE is conducting a multiyear project to develop evaluation guidelines for assessing the condition and determining the need for upgrades at DOE facilities. One element of the NPH evaluation guidelines' development involves the existing systems and components at DOE facilities. This effort is described in detail in a cited reference. In the interim period prior to availability of the final guidelines, DOE facilities are encouraged to implement an NPH walk through screening evaluation process by which systems and components that need attention can be rapidly identified. Guidelines for conducting the walk through screening evaluations are contained herein. The result of the NPH walk through screening evaluation should be a prioritized list of systems and components that need further action. Simple and inexpensive fixes for items identified in the walk through as marginal or inadequate should be implemented without further study. By implementing an NPH walk through screening evaluation, DOE facilities may realize significant reduction in risk from NPH in the short term

OneGeology Web Services and Portal as a global geological SDI - latest standards and technology

Science.gov (United States)

Duffy, Tim; Tellez-Arenas, Agnes

2014-05-01

The global coverage of OneGeology Web Services (www.onegeology.org and portal.onegeology.org) achieved since 2007 from the 120 participating geological surveys will be reviewed and issues arising discussed. Recent enhancements to the OneGeology Web Services capabilities will be covered including new up to 5 star service accreditation scheme utilising the ISO/OGC Web Mapping Service standard version 1.3, core ISO 19115 metadata additions and Version 2.0 Web Feature Services (WFS) serving the new IUGS-CGI GeoSciML V3.2 geological web data exchange language standard (http://www.geosciml.org/) with its associated 30+ IUGS-CGI available vocabularies (http://resource.geosciml.org/ and http://srvgeosciml.brgm.fr/eXist2010/brgm/client.html). Use of the CGI simpelithology and timescale dictionaries now allow those who wish to do so to offer data harmonisation to query their GeoSciML 3.2 based Web Feature Services and their GeoSciML_Portrayal V2.0.1 (http://www.geosciml.org/) Web Map Services in the OneGeology portal (http://portal.onegeology.org). Contributing to OneGeology involves offering to serve ideally 1:1000,000 scale geological data (in practice any scale now is warmly welcomed) as an OGC (Open Geospatial Consortium) standard based WMS (Web Mapping Service) service from an available WWW server. This may either be hosted within the Geological Survey or a neighbouring, regional or elsewhere institution that offers to serve that data for them i.e. offers to help technically by providing the web serving IT infrastructure as a 'buddy'. OneGeology is a standards focussed Spatial Data Infrastructure (SDI) and works to ensure that these standards work together and it is now possible for European Geological Surveys to register their INSPIRE web services within the OneGeology SDI (e.g. see http://www.geosciml.org/geosciml/3.2/documentation/cookbook/INSPIRE_GeoSciML_Cookbook%20_1.0.pdf). The Onegeology portal (http://portal.onegeology.org) is the first port of call for anyone

Revised draft: Northeastern Regional geologic characterization report. Volume 1

International Nuclear Information System (INIS)

1984-11-01

This report presents available geologic information pertinent to siting a repository for high-level nuclear waste in crystalline rock in Connecticut, Maine, Massachusetts, New Hampshire, New Jersey, New York, Pennsylvania, Rhode Island, and Vermont. For each of the states within the Northeastern Region, information is provided on the disqualifying factor and the screening variables to be used in region-to-area screening. These factors and variables include: hydrologically significant natural resources, rock mass extent, post-emplacement faulting, suspected Quaternary faulting, seismicity, rock and mineral resources, major ground-water discharge zones, water resources, ground-water salinity, and state of stress. Information is presented on its age, areal extent, shape, thickness of overburden, composition, texture, degree and type of alteration, rock mass thickness, and structural features associated with each rock body or complex. Regional seismic and tectonic information is presented, including patterns of earthquake occurrence, earthquake magnitudes, horizontal ground accelerations, and vertical crustal movements. Also included are discussions of the rock and mineral deposits or mines located within or near crystalline bodies; ground-water resources and regional hydrology; postulated changes in climate and the associated effects; and landforms, surface processes, and surficial materials on or near the subject rock bodies

Operation environment construction of geological information database for high level radioactive waste geological disposal

International Nuclear Information System (INIS)

Wang Peng; Gao Min; Huang Shutao; Wang Shuhong; Zhao Yongan

2014-01-01

To fulfill the requirements of data storage and management in HLW geological disposal, a targeted construction method for data operation environment was proposed in this paper. The geological information database operation environment constructed by this method has its unique features. And it also will be the important support for HLW geological disposal project and management. (authors)

Evaluating radiographers' diagnostic accuracy in screen-reading mammograms: what constitutes a quality study?

International Nuclear Information System (INIS)

Debono, Josephine C; Poulos, Ann E

2015-01-01

The aim of this study was to first evaluate the quality of studies investigating the diagnostic accuracy of radiographers as mammogram screen-readers and then to develop an adapted tool for determining the quality of screen-reading studies. A literature search was used to identify relevant studies and a quality evaluation tool constructed by combining the criteria for quality of Whiting, Rutjes, Dinnes et al. and Brealey and Westwood. This constructed tool was then applied to the studies and subsequently adapted specifically for use in evaluating quality in studies investigating diagnostic accuracy of screen-readers. Eleven studies were identified and the constructed tool applied to evaluate quality. This evaluation resulted in the identification of quality issues with the studies such as potential for bias, applicability of results, study conduct, reporting of the study and observer characteristics. An assessment of the applicability and relevance of the tool for this area of research resulted in adaptations to the criteria and the development of a tool specifically for evaluating diagnostic accuracy in screen-reading. This tool, with further refinement and rigorous validation can make a significant contribution to promoting well-designed studies in this important area of research and practice

Planetary Geologic Mapping Handbook - 2009

Science.gov (United States)

Tanaka, K. L.; Skinner, J. A.; Hare, T. M.

2009-01-01

Geologic maps present, in an historical context, fundamental syntheses of interpretations of the materials, landforms, structures, and processes that characterize planetary surfaces and shallow subsurfaces (e.g., Varnes, 1974). Such maps also provide a contextual framework for summarizing and evaluating thematic research for a given region or body. In planetary exploration, for example, geologic maps are used for specialized investigations such as targeting regions of interest for data collection and for characterizing sites for landed missions. Whereas most modern terrestrial geologic maps are constructed from regional views provided by remote sensing data and supplemented in detail by field-based observations and measurements, planetary maps have been largely based on analyses of orbital photography. For planetary bodies in particular, geologic maps commonly represent a snapshot of a surface, because they are based on available information at a time when new data are still being acquired. Thus the field of planetary geologic mapping has been evolving rapidly to embrace the use of new data and modern technology and to accommodate the growing needs of planetary exploration. Planetary geologic maps have been published by the U.S. Geological Survey (USGS) since 1962 (Hackman, 1962). Over this time, numerous maps of several planetary bodies have been prepared at a variety of scales and projections using the best available image and topographic bases. Early geologic map bases commonly consisted of hand-mosaicked photographs or airbrushed shaded-relief views and geologic linework was manually drafted using mylar bases and ink drafting pens. Map publishing required a tedious process of scribing, color peel-coat preparation, typesetting, and photo-laboratory work. Beginning in the 1990s, inexpensive computing, display capability and user-friendly illustration software allowed maps to be drawn using digital tools rather than pen and ink, and mylar bases became obsolete

Screening Criteria for Ophthalmic Manifestations of Congenital Zika Virus Infection.

Science.gov (United States)

Zin, Andrea A; Tsui, Irena; Rossetto, Julia; Vasconcelos, Zilton; Adachi, Kristina; Valderramos, Stephanie; Halai, Umme-Aiman; Pone, Marcos Vinicius da Silva; Pone, Sheila Moura; Silveira Filho, Joel Carlos Barros; Aibe, Mitsue S; da Costa, Ana Carolina C; Zin, Olivia A; Belfort, Rubens; Brasil, Patricia; Nielsen-Saines, Karin; Moreira, Maria Elisabeth Lopes

2017-09-01

Current guidelines recommend screening eye examinations for infants with microcephaly or laboratory-confirmed Zika virus infection but not for all infants potentially exposed to Zika virus in utero. To evaluate eye findings in a cohort of infants whose mothers had polymerase chain reaction-confirmed Zika virus infection during pregnancy. In this descriptive case series performed from January 2 through October 30, 2016, infants were examined from birth to 1 year of age by a multidisciplinary medical team, including a pediatric ophthalmologist, from Fernandes Figueira Institute, a Ministry of Health referral center for high-risk pregnancies and infectious diseases in children in Rio de Janeiro, Brazil. Mother-infant pairs from Rio de Janeiro, Brazil, who presented with suspected Zika virus infection during pregnancy were referred to our institution and had serum, urine, amniotic fluid, or placenta samples tested by real-time polymerase chain reaction for Zika virus. Description of eye findings, presence of microcephaly or other central nervous system abnormalities, and timing of infection in infants with confirmed Zika virus during pregnancy. Eye abnormalities were correlated with central nervous system findings, microcephaly, and the timing of maternal infection. Of the 112 with polymerase chain reaction-confirmed Zika virus infection in maternal specimens, 24 infants (21.4%) examined had eye abnormalities (median age at first eye examination, 31 days; range, 0-305 days). Ten infants (41.7%) with eye abnormalities did not have microcephaly, and 8 (33.3%) did not have any central nervous system findings. Fourteen infants with eye abnormalities (58.3%) were born to women infected in the first trimester, 8 (33.3%) in the second trimester, and 2 (8.3%) in the third trimester. Optic nerve and retinal abnormalities were the most frequent findings. Eye abnormalities were statistically associated with microcephaly (odds ratio [OR], 19.1; 95% CI, 6.0-61.0), other central

Can long term criteria for deep disposal be implemented

International Nuclear Information System (INIS)

Bragg, K.

1994-01-01

Over the last decade considerable time and effort has been devoted to the development of criteria for the disposal of long-lived waste into deep geological environments. Now the focus is shifting to the more practical problems associated with applying these criteria and demonstrating compliance. Time and effort is being spent on exploring the various compliance options and in determining how much information is needed for compliance and what form it should take. These decisions are further complicated because there are a variety of target audiences which need to be addressed and the types of open-quotes proofclose quotes which each needs to reflect their preferences and orientations can vary greatly. The fundamental need however is to provide material that leads all these groups to a sufficient level of confidence that the decisions they must make are adequately supported. This paper will explore these diverse requirements and in particular emphasize some of the polarities involved. Examples of these are: simplicity versus complexity; comprehensiveness versus understandability; variety of approach versus choosing the optimal one; technical versus social orientation; and, general performance targets versus specific design objectives

Performance and Cost-Effectiveness of Computed Tomography Lung Cancer Screening Scenarios in a Population-Based Setting: A Microsimulation Modeling Analysis in Ontario, Canada.

Directory of Open Access Journals (Sweden)

Kevin Ten Haaf

2017-02-01

Full Text Available The National Lung Screening Trial (NLST results indicate that computed tomography (CT lung cancer screening for current and former smokers with three annual screens can be cost-effective in a trial setting. However, the cost-effectiveness in a population-based setting with >3 screening rounds is uncertain. Therefore, the objective of this study was to estimate the cost-effectiveness of lung cancer screening in a population-based setting in Ontario, Canada, and evaluate the effects of screening eligibility criteria.This study used microsimulation modeling informed by various data sources, including the Ontario Health Insurance Plan (OHIP, Ontario Cancer Registry, smoking behavior surveys, and the NLST. Persons, born between 1940 and 1969, were examined from a third-party health care payer perspective across a lifetime horizon. Starting in 2015, 576 CT screening scenarios were examined, varying by age to start and end screening, smoking eligibility criteria, and screening interval. Among the examined outcome measures were lung cancer deaths averted, life-years gained, percentage ever screened, costs (in 2015 Canadian dollars, and overdiagnosis. The results of the base-case analysis indicated that annual screening was more cost-effective than biennial screening. Scenarios with eligibility criteria that required as few as 20 pack-years were dominated by scenarios that required higher numbers of accumulated pack-years. In general, scenarios that applied stringent smoking eligibility criteria (i.e., requiring higher levels of accumulated smoking exposure were more cost-effective than scenarios with less stringent smoking eligibility criteria, with modest differences in life-years gained. Annual screening between ages 55-75 for persons who smoked ≥40 pack-years and who currently smoke or quit ≤10 y ago yielded an incremental cost-effectiveness ratio of $41,136 Canadian dollars ($33,825 in May 1, 2015, United States dollars per life-year gained

Screening of the frail patient in the emergency department

DEFF Research Database (Denmark)

Jørgensen, Rasmus; Brabrand, Mikkel

2017-01-01

to detect frailty in patients. ≥. 65. years by their ability to identify the risk of adverse outcomes. Methods: An extensive medical literature search of Embase and PubMed was conducted, to identify studies using frailty screening scales in the emergency department. Data was subsequently extracted...... and evaluated from the results of the included studies. Results: Four studies met the exact inclusion criteria. Four different frailty screening scales: Clinical Frailty Scale, Deficit Accumulation Index, Identification of Seniors At Risk and The Study of Osteoporotic Fracture frailty index used...... emergency department visit. Frailty does however not predict increased risk of 30. day emergency department revisit. Further research highlighting the value of screening for frailty level in elderly emergency department patients is needed. Learning points: Although frail elders in need of further geriatric...

Monitored retrievable storage facility site screening and evaluation report

International Nuclear Information System (INIS)

1985-05-01

The Nuclear Waste Policy Act of 1982 directs the Department of Energy to ''complete a detailed study of the need for and feasibility of, and to submit to the Congress a proposal for, the construction of one or more monitored retrievable storage facilities for high level radioactive waste and spent nuclear fuel.'' The Act directs that the proposal includes site specific designs. Further, the proposal is to include, ''for the first such facility, at least three alternative sites and at least five alternative combinations of such proposed site and facility designs...'' as well as a recommendation of ''the combination among the alternatives that the Secretary deems preferable.'' An MRS Site Screening Task Force has been formed to help identify and evaluated potential MRS facility sites within a preferred region and with the application of a siting process and criteria developed by the DOE. The activities of the task force presented in this report includes: site screening (Sections 3, 4, and 5), the MRS facilities which are to be sited are described; the criteria, process and outcome of the screening process is presented; and descriptions of the candidate MRS facility sites are given, and site evaluations (Sections 6 through 9) where the rational for the site evaluations are presented, along with each evaluation and findings of the Task Force

Monitored retrievable storage facility site screening and evaluation report

Energy Technology Data Exchange (ETDEWEB)

none,

1985-05-01

The Nuclear Waste Policy Act of 1982 directs the Department of Energy to complete a detailed study of the need for and feasibility of, and to submit to the Congress a proposal for, the construction of one or more monitored retrievable storage facilities for high level radioactive waste and spent nuclear fuel.'' The Act directs that the proposal includes site specific designs. Further, the proposal is to include, for the first such facility, at least three alternative sites and at least five alternative combinations of such proposed site and facility designs...'' as well as a recommendation of the combination among the alternatives that the Secretary deems preferable.'' An MRS Site Screening Task Force has been formed to help identify and evaluated potential MRS facility sites within a preferred region and with the application of a siting process and criteria developed by the DOE. The activities of the task force presented in this report includes: site screening (Sections 3, 4, and 5), the MRS facilities which are to be sited are described; the criteria, process and outcome of the screening process is presented; and descriptions of the candidate MRS facility sites are given, and site evaluations (Sections 6 through 9) where the rational for the site evaluations are presented, along with each evaluation and findings of the Task Force.

A Screening Tool for Assessing Alcohol Use Risk among Medically Vulnerable Youth.

Science.gov (United States)

Levy, Sharon; Dedeoglu, Fatma; Gaffin, Jonathan M; Garvey, Katharine C; Harstad, Elizabeth; MacGinnitie, Andrew; Rufo, Paul A; Huang, Qian; Ziemnik, Rosemary E; Wisk, Lauren E; Weitzman, Elissa R

2016-01-01

In an effort to reduce barriers to screening for alcohol use in pediatric primary care, the National Institute on Alcoholism and Alcohol Abuse (NIAAA) developed a two-question Youth Alcohol Screening Tool derived from population-based survey data. It is unknown whether this screening tool, designed for use with general populations, accurately identifies risk among youth with chronic medical conditions (YCMC). This growing population, which comprises nearly one in four youth in the US, faces a unique constellation of drinking-related risks. To validate the NIAAA Youth Alcohol Screening Tool in a population of YCMC, we performed a cross-sectional validation study with a sample of 388 youth ages 9-18 years presenting for routine subspecialty care at a large children's hospital for type 1 diabetes, persistent asthma, cystic fibrosis, inflammatory bowel disease, or juvenile idiopathic arthritis. Participants self-administered the NIAAA Youth Alcohol Screening Tool and the Diagnostic Interview Schedule for Children as a criterion standard measure of alcohol use disorders (AUD). Receiver operating curve analysis was used to determine cut points for identifying youth at moderate and highest risk for an AUD. Nearly one third of participants (n = 118; 30.4%) reported alcohol use in the past year; 86.4% (106) of past year drinkers did not endorse any AUD criteria, 6.8% (n = 8) of drinkers endorsed a single criterion, and 6.8% of drinkers met criteria for an AUD. Using the NIAAA tool, optimal cut points found to identify youth at moderate and highest risk for an AUD were ≥ 6 and ≥12 drinking days in the past year, respectively. The NIAAA Youth Alcohol Screening Tool is highly efficient for detecting alcohol use and discriminating disordered use among YCMC. This brief screen appears feasible for use in specialty care to ascertain alcohol-related risk that may impact adversely on health status and disease management.

The malnutrition screening tool versus objective measures to detect malnutrition in hip fracture.

Science.gov (United States)

Bell, J J; Bauer, J D; Capra, S

2013-12-01

The Malnutrition Screening Tool (MST) is the most commonly used screening tool in Australia. Poor screening tool sensitivity may lead to an under-diagnosis of malnutrition, with potential patient and economic ramifications. The present study aimed to determine whether the MST or anthropometric parameters adequately detect malnutrition in patients who were admitted to a hip fracture unit. Data were analysed for a prospective convenience sample (n = 100). MST screening was independently undertaken by nursing staff and a nutrition assistant. Mid upper arm circumference (MUAC) was measured by a trained nutrition assistant. Nutritional risk [MST score ≥ 2, body mass index (BMI) malnutrition diagnosed by accredited practicing dietitians using International Classification of Diseases version 10-Australian Modification (ICD10-AM) coding criteria. Malnutrition prevalence was 37.5% using ICD10-AM criteria. Delirium, dementia or preadmission cognitive impairment was present in 65% of patients. The BMI as a nutrition risk screen was the most valid predictor of malnutrition (sensitivity 75%; specificity 93%; positive predictive value 73%; negative predictive value 84%). Nursing MST screening was the least valid (sensitivity 73%; specificity 55%; positive predictive value 50%; negative predictive value 77%). There was only fair agreement between nursing and nutrition assistant screening using the MST (κ = 0.28). In this population with a high prevalence of delirium and dementia, further investigation is warranted into the performance of nutrition screening tools and anthropometric parameters such as BMI. All tools failed to predict a considerable number of patients with malnutrition. This may result in the under-diagnosis and treatment of malnutrition, leading to case-mix funding losses. © 2013 The Authors Journal of Human Nutrition and Dietetics © 2013 The British Dietetic Association Ltd.

Identification of Aircraft Hazards

International Nuclear Information System (INIS)

K. Ashley

2006-01-01

Aircraft hazards were determined to be potentially applicable to a repository at Yucca Mountain in ''Monitored Geological Repository External Events Hazards Screening Analysis'' (BSC 2005 [DIRS 174235], Section 6.4.1). That determination was conservatively based upon limited knowledge of flight data in the area of concern and upon crash data for aircraft of the type flying near Yucca Mountain. The purpose of this report is to identify specific aircraft hazards that may be applicable to a monitored geologic repository (MGR) at Yucca Mountain, using NUREG-0800, ''Standard Review Plan for the Review of Safety Analysis Reports for Nuclear Power Plants'' (NRC 1987 [DIRS 103124], Section 3.5.1.6), as guidance for the inclusion or exclusion of identified aircraft hazards. The intended use of this report is to provide inputs for further screening and analysis of identified aircraft hazards based upon the criteria that apply to Category 1 and Category 2 event sequence analyses as defined in 10 CFR 63.2 [DIRS 176544] (Section 4). The scope of this report includes the evaluation of military, private, and commercial use of airspace in the 100-mile regional setting of the repository at Yucca Mountain with the potential for reducing the regional setting to a more manageable size after consideration of applicable screening criteria (Section 7)

Derivation and validation of REASON: a risk score identifying candidates to screen for peripheral arterial disease using ankle brachial index.

Science.gov (United States)

Ramos, Rafel; Baena-Díez, Jose Miguel; Quesada, Miquel; Solanas, Pascual; Subirana, Isaac; Sala, Joan; Alzamora, Maite; Forès, Rosa; Masiá, Rafel; Elosua, Roberto; Grau, María; Cordón, Ferran; Pera, Guillem; Rigo, Fernando; Martí, Ruth; Ponjoan, Anna; Cerezo, Carlos; Brugada, Ramon; Marrugat, Jaume

2011-02-01

The recommendation of screening with ankle brachial index (ABI) in asymptomatic individuals is controversial. The aims of the present study were to develop and validate a pre-screening test to select candidates for ABI measurement in the Spanish population 50-79 years old, and to compare its predictive capacity to current Inter-Society Consensus (ISC) screening criteria. Two population-based cross-sectional studies were used to develop (n = 4046) and validate (n = 3285) a regression model to predict ABI guidelines, and similar sensitivity. This resulted in fewer patients screened per diagnosis of ABI < 0.9 (10.6 vs. 8.75) and a lower proportion of the population aged 50-79 years candidate to ABI screening (63.3% vs. 55.0%). This model provides accurate ABI < 0.9 risk estimates for ages 50-79, with a better predictive capacity than that of ISC criteria. Its use could reduce possible harms and unnecessary work-ups of ABI screening as a risk stratification strategy in primary prevention of peripheral vascular disease. Copyright © 2010 Elsevier Ireland Ltd. All rights reserved.

Origins of Sinuous and Braided Channels on Ascraeus Mons, Mars - A Keck Geology Consortium Undergraduate Research Project

Science.gov (United States)

de Wet, A. P.; Bleacher, J. E.; Garry, W. B.

2012-01-01

Water has clearly played an important part in the geological evolution of Mars. There are many features on Mars that were almost certainly formed by fluvial processes -- for example, the channels Kasei Valles and Ares Vallis in the Chryse Planitia area of Mars are almost certainly fluvial features. On the other hand, there are many channel features that are much more difficult to interpret -- and have been variously attributed to volcanic and fluvial processes. Clearly unraveling the details of the role of water on Mars is extremely important, especially in the context of the search of extinct or extant life. In this project we built on our recent work in determining the origin of one channel on the southwest rift apron of Ascraeus Mons. This project, funded by the Keck Geology Consortium and involving 4 undergraduate geology majors took advantage of the recently available datasets to map and analyze similar features on Ascraeus Mons and some other areas of Mars. A clearer understanding of how these particular channel features formed might lead to the development of better criteria to distinguish how other Martian channel features formed. Ultimately this might provide us with a better understanding of the role of volcanic and fluvial processes in the geological evolution of Mars.

Role of waste packages in the safety of a high level waste repository in a deep geological formation

International Nuclear Information System (INIS)

Bretheau, F.; Lewi, J.

1990-06-01

The safety of a radioactive waste disposal facility lays on the three following barriers placed between the radioactive materials and the biosphere: the waste package; the engineered barriers; the geological barrier. The function assigned to each of these barriers in the performance assessment is an option taken by the organization responsible for waste disposal management (ANDRA in France), which must show that: expected performances of each barrier (confinement ability, life-time, etc.) are at least equal to those required to fulfill the assigned function; radiation protection requirements are met in all situations considered as credible, whether they be the normal situation or random event situations. The French waste management strategy is based upon two types of disposal depending on the nature and activity of waste packages: - surface disposal intended for low and medium level wastes having half-lives of about 30 years or less and alpha activity less than 3.7 MBq/kg (0.1 Ci/t), for individual packages and less than 0.37 MBq/kg (0.01 Ci/t) in the average. Deep geological disposal intended for TRU and high level wastes. The conditions of acceptance of packages in a surface disposal site are subject to the two fundamental safety rules no. I.2 and III.2.e. The present paper is only dealing with deep geological disposal. For deep geological repositories, three stages are involved: stage preceding definitive disposal (intermediate storage, transportation, handling, setting up in the disposal cavities); stage subsequent to definitive sealing of the disposal cavities but prior to the end of operation of the repository; stage subsequent to closure of the repository. The role of the geological barrier has been determined as the essential part of long term radioactivity confinement, by a working group, set up by the French safety authorities. Essential technical criteria relating to the choice of a site so defined by this group, are the following: very low permeability

Canada's deep geological repository for used nuclear fuel - update on the site evaluation process and interweaving of aboriginal traditional knowledge

International Nuclear Information System (INIS)

Watts, B.; Belfadhel, M.B.; Facella, J.

2015-01-01

The Nuclear Waste Management Organization (NWMO) is responsible for implementing Adaptive Phased Management (APM), the approach selected by the Government of Canada for the long-term management of used nuclear fuel generated by Canadian nuclear reactors. The ultimate objective of APM is the centralized containment and isolation of Canada's used nuclear fuel in a Deep Geological Repository (DGR) in a suitable crystalline or sedimentary rock formation. In May 2010, the NWMO initiated a nine-step site selection process to seek an informed and willing community to host Canada's deep geological repository. As of April 2015, twenty-two communities expressed interest in learning more about the project. This paper provides an update on the site evaluation process and describes the approach, methods and criteria used in the assessments, focusing on geological and community well-being studies. Engagement and field activities to interweave Aboriginal Traditional Knowledge with western science are also discussed. (author)

[Screening of adverse childhood experiences in preschoolers: scoping review].

Science.gov (United States)

Vega-Arce, Maribel; Núñez-Ulloa, Gastón

The aim of the present article was to describe available scientific publications detailing strategies and screening tools for Adverse Childhood Experiences in preschoolers (2 to 5 years of age). A scoping review of the topic was carried out through investigative articles published in peer review journals from January 1998 to June 2017 and indexed in seven international databases (Cochrane Library, EBSCO, PubMed, Science Direct, Springer, Web of Science and Scielo). The articles were selected based on predefined criteria, using limiters and manual screening. Twenty articles published between 1999 and 2017 were selected. The screening of adverse childhood experiences is performed through opportunistic recruitment in a professional context aimed at caregivers and children, which integrates training actions, application of screening tools and reception of identified cases. Screening tools differ between interviews and questionnaires. Furthermore, we report the periodicity of the screening, the behaviors and beliefs of the professionals against it and the barriers to its implementation. This review confirms that the screening of Adverse Childhood Experiences is an emerging topic in the research field. We emphasize the need to systematize and evaluate the strategies and tools for screening Adverse Childhood Experiences, as well as to develop local approaches to respond to the needs of children exposed to adversity. Copyright © 2017 Hospital Infantil de México Federico Gómez. Publicado por Masson Doyma México S.A. All rights reserved.

Engineering geology and environmental protection

Energy Technology Data Exchange (ETDEWEB)

Sergeev, E M

1979-01-01

A classification is made of the anthropogenic processes in the environment into global, local, universally distributed, zonal, regional, and essentially local processes. Engineering geology is defined as the principal science concerned with the study of the geological medium which in turn involves the study of fossil fuel geology. 22 references.