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Sample records for genesis

  1. Genesis machines

    CERN Document Server

    Amos, Martyn

    2014-01-01

    Silicon chips are out. Today's scientists are using real, wet, squishy, living biology to build the next generation of computers. Cells, gels and DNA strands are the 'wetware' of the twenty-first century. Much smaller and more intelligent, these organic computers open up revolutionary possibilities. Tracing the history of computing and revealing a brave new world to come, Genesis Machines describes how this new technology will change the way we think not just about computers - but about life itself.

  2. Lean Management Genesis

    Directory of Open Access Journals (Sweden)

    Parkes Aneta

    2015-12-01

    Full Text Available Lean Management is a philosophy and management concept, based on reduction of the waste and resources used in the process of producing goods and providing services. Lean Management genesis dates back to scientific management in America (for example concepts of H. Ford and F.W. Taylor and quality management, including development of TQM concept. Japanese Toyota Production System has been inspired by chosen elements of these concepts, and then it evolved towards global concept called Toyota Way (which connects production rules with values and work attitude.

  3. Genesis nature of financial strategy

    OpenAIRE

    O.V. Pashchenko

    2015-01-01

    The article is devoted to the study of the origin and history of the interpretation of the genesis of «strategy», «financial strategy», its elements and composite types. Scientists studied different views on the concept of strategy. Several specific positions founders of different approaches to define the strategy of schools operating strategies involved in the formulation and implementation of the concept of «strategy». Evaluation of different schools of strategies that deepened understandin...

  4. PROFESSIONALISM: GENESIS AND CATEGORICAL ANALYSES

    Directory of Open Access Journals (Sweden)

    Ирина Олеговна Авдеева

    2013-12-01

    Full Text Available In the article the theoretical-methodological analysis of the concept of «professional», describes the genesis and key aspects of its content and structure. In addition, this publication discusses some of the approaches to the definition of the studied concepts, including: system (professional it seems as multipart strictly organized education of consciousness and psyche of the individual; professional graphic (from a position of objective (professional description and subjective (mental graph the parties; integrative (as property, process, and status of the person; acmeological (as the dialectical the unity of the personality and activity components; in terms of motivation and operating parties and other Stresses the importance of personal (theoretical knowledge, professional qualities, value orientations, motivational orientation of others and specific features of labour employee (practical skills, professional experience and other, determining the effectiveness of its activities.DOI: http://dx.doi.org/10.12731/2218-7405-2013-10-12

  5. G3 : GENESIS software envrionment update

    OpenAIRE

    Castagné, Nicolas; Cadoz, Claude; Allaoui, Ali; Tache, Olivier Michel

    2009-01-01

    GENESIS3 is the new version of the GENESIS software environment for musical creation by means of mass-interaction physics network modeling. It was designed, and developed from scratch, in hindsight of more than 10 years working on and using the previous version. We take the opportunity of this birth to provide in this article (1) an analysis of the peculiarities in GENESIS, aiming at highlighting its core ?software paradigm?; and (2) an update on the features of the new version as compared to...

  6. Genesis / Juta Kivimäe

    Index Scriptorium Estoniae

    Kivimäe, Juta, 1952-

    2003-01-01

    Poola skulptori Magdalena Schmidt-G̤ra installatsioonid "Genesis I, II" rahvusraamatukogu fuajees ja peanäitusesaalis, kus oli samal ajal eksponeeritud eesti nahakunstnike Luule Maari ja Ruuda Maarandi köitenäitus

  7. Genesis and Development of Consolidated Financial Statements

    OpenAIRE

    Kostyantyn Bezverkhiy

    2015-01-01

    In the context of economy globalization it is the mission of consolidated financial statements to meet demands of users for financial information about activities of a company group as one company. The article is devoted to study of genesis and development of consolidated financial statements of companies. Historical prerequisites of genesis of consolidated financial statements are shown as well as factors which conduced to their spreading. The approaches are elucidated to preparation of cons...

  8. Fullerene genesis by ion beams

    International Nuclear Information System (INIS)

    Gamaly, E.G.; Chadderton, L.T.; Commonwealth Scientific and Industrial Research Organization, Lindfield, NSW

    1995-01-01

    Clearly detectable quantities of molecular fullerene (C 60 ), the most recently discovered allotrope of carbon, have been observed in graphite following irradiation with heavy projectile ions at energies of about 1 GeV using high pressure chromatography. Similar experiments using lower ion energies gave no corresponding signal, indicating an absence of fullerene. This clear difference suggests that there exists an energy threshold for fullerene genesis. Beginning with a microscopic description of deposition and transfer of energy from the ion to the target, a theoretical model is developed for interpretation of these and similar experiments. An important consequence is a description of the formation of large carbon clusters in the hot dense 'primeval soup' of single carbon atoms by means of random 'sticky' collisions. The ion energy threshold is seen as arising, physically, from a balance in the competition between the rate of primary energy deposition and the rate of system cooling. Rate equations for the basic clustering process allow calculations of the time-dependent number densities for the different carbon clusters produced. An important consequence of the theory is that it is established that the region for the specific phase transition from graphite to fullerene lies in the same pressure regime on the phase diagram as does the corresponding transition for graphite to diamond. (author)

  9. Genesis nature of financial strategy

    Directory of Open Access Journals (Sweden)

    O.V. Pashchenko

    2015-03-01

    Full Text Available The article is devoted to the study of the origin and history of the interpretation of the genesis of «strategy», «financial strategy», its elements and composite types. Scientists studied different views on the concept of strategy. Several specific positions founders of different approaches to define the strategy of schools operating strategies involved in the formulation and implementation of the concept of «strategy». Evaluation of different schools of strategies that deepened understanding of the industry and its strategy in the early stages of formation. Based on the works of various scholars studied by the author actually proposed interpretation of the concept strategy. The general industry and functional strategies which include the following strategies: innovation, resource, financial, production, marketing and human resources. Allocated financial strategy and its significant impact on other strategies. Author developed financial sector strategy and financial strategy of competitive enterprise. The importance of financial strategies under conditions of companies and the industry as a whole, as well as components of development of financial strategy. Deals with the factors that must be considered in the development and implementation of financial strategies. The systems analysis strategies and the impact on financial results, the estimation of their attractiveness and risk. Considered classification on the basis of financial strategies and sectoral orientation of the financial sector strategy based on company size, its form and noted the importance of this trait in systematizing strategies. The expediency of the financial strategy. Defined competitive advantage and efficiency of business and industry through the implementation of various financial strategies.

  10. New Results from the Flare Genesis Experiment

    Science.gov (United States)

    Rust, D. M.; Bernasconi, P. N.; Eaton, H. A.; Keller, C.; Murphy, G. A.; Schmieder, B.

    2000-05-01

    From January 10 to 27, 2000, the Flare Genesis solar telescope observed the Sun while suspended from a balloon in the stratosphere above Antarctica. The goal of the mission was to acquire long time series of high-resolution images and vector magnetograms of the solar photosphere and chromosphere. Images were obtained in the magnetically sensitive Ca I line at 6122 Angstroms and at H-alpha (6563 Angstroms). The FGE data were obtained in the context of Max Millennium Observing Campaign #004, the objective of which was to study the ``Genesis of Solar Flares and Active Filaments/Sigmoids." Flare Genesis obtained about 26,000 usable images on the 8 targeted active regions. A preliminary examination reveals a good sequence on an emerging flux region and data on the M1 flare on January 22, as well as a number of sequences on active filaments. We will present the results of our first analysis efforts. Flare Genesis was supported by NASA grants NAG5-4955, NAG5-5139, and NAG5-8331 and by NSF grant OPP-9615073. The Air Force Office of Scientific Research and the Ballistic Missile Defense Organization supported early development of the Flare Genesis Experiment.

  11. Cosmological bounce and Genesis beyond Horndeski

    Energy Technology Data Exchange (ETDEWEB)

    Kolevatov, R.; Mironov, S.; Volkova, V. [Institute for Nuclear Research of the Russian Academy of Sciences, 60th October Anniversary Prospect, 7a, 117312 Moscow (Russian Federation); Sukhov, N., E-mail: kolevatov@ms2.inr.ac.ru, E-mail: sa.mironov_1@physics.msu.ru, E-mail: nd.sukhov@physics.msu.ru, E-mail: volkova.viktoriya@physics.msu.ru [Department of Particle Physics and Cosmology, Physics Faculty, M.V. Lomonosov Moscow State University, Vorobjevy Gory, 119991 Moscow (Russian Federation)

    2017-08-01

    We study 'classical' bouncing and Genesis models in beyond Horndeski theory. We give an example of spatially flat bouncing solution that is non-singular and stable throughout the whole evolution. We also provide an example of stable geodesically complete Genesis with similar features. The model is arranged in such a way that the scalar field driving the cosmological evolution initially behaves like full-fledged beyond Horndeski, whereas at late times it becomes a massless scalar field minimally coupled to gravity.

  12. Generalized Galileons: instabilities of bouncing and Genesis cosmologies and modified Genesis

    Energy Technology Data Exchange (ETDEWEB)

    Libanov, M. [Institute for Nuclear Research of the Russian Academy of Sciences,60th October Anniversary Prospect 7a, 117312 Moscow (Russian Federation); Moscow Institute of Physics and Technology,Institutskii per. 9, 141700 Dolgoprudny, Moscow Region (Russian Federation); Mironov, S. [Institute for Nuclear Research of the Russian Academy of Sciences,60th October Anniversary Prospect 7a, 117312 Moscow (Russian Federation); Rubakov, V. [Institute for Nuclear Research of the Russian Academy of Sciences,60th October Anniversary Prospect 7a, 117312 Moscow (Russian Federation); Department of Particle Physics and Cosmology, Physics Faculty,M.V. Lomonosov Moscow State University,Vorobjevy Gory, 119991, Moscow (Russian Federation)

    2016-08-18

    We study spatially flat bouncing cosmologies and models with the early-time Genesis epoch in a popular class of generalized Galileon theories. We ask whether there exist solutions of these types which are free of gradient and ghost instabilities. We find that irrespectively of the forms of the Lagrangian functions, the bouncing models either are plagued with these instabilities or have singularities. The same result holds for the original Genesis model and its variants in which the scale factor tends to a constant as t→−∞. The result remains valid in theories with additional matter that obeys the Null Energy Condition and interacts with the Galileon only gravitationally. We propose a modified Genesis model which evades our no-go argument and give an explicit example of healthy cosmology that connects the modified Genesis epoch with kination (the epoch still driven by the Galileon field, which is a conventional massless scalar field at that stage).

  13. Finding the Genesis for a Thesis

    Science.gov (United States)

    Caroll, Joyce Armstrong

    2013-01-01

    This article describes a prewriting heuristics strategy that can help students find the genesis of their thesis. The 3 functions of the heuristic procedure are that it aids in retrieving relevant information stored in the mind; draws attention to important information that can be further researched or accessed; and prepares the mind for the…

  14. Photovoltaic technologies and the genesis project

    International Nuclear Information System (INIS)

    Kuwano, Y.

    1994-01-01

    In this paper, the author first presents briefly global environmental problems and energy problems, as well as recent trends in representative types of solar cell. Next, he gives examples of applications for these solar cells, and finally discusses future prospects for solar cells in the form of the GENESIS project. (TEC). 12 figs., 4 refs

  15. ABRAHAM IN GALATIANS AND IN GENESIS1

    African Journals Online (AJOL)

    In Genesis 12-25, attention is paid to the promise of land and on Abraham as a blessing to ... It is a truism to claim that Abraham serves as an important figure in both the ..... them rest (Jos 21:43), became the ground for hope for the people who.

  16. 76 FR 54454 - Issuance of Loan Guarantee to Genesis Solar, LLC, for the Genesis Solar Energy Project

    Science.gov (United States)

    2011-09-01

    ... DEPARTMENT OF ENERGY Issuance of Loan Guarantee to Genesis Solar, LLC, for the Genesis Solar... Energy Project (GSEP), a 250-megawatt (MW) nominal capacity solar power generating facility on.../Final Environmental Impact Statement for the Genesis Solar Energy Project, Riverside County, California...

  17. Origins, transformations and key foci in instrumental genesis

    DEFF Research Database (Denmark)

    Tamborg, Andreas Lindenskov

    This paper investigates the origins of the instrumental genesis and instrumental orchestrations frameworks. This is done by reviewing instrumented activity situations, instrumental genesis, and instrumental orchestrations with the purpose of identifying their epistemological assumptions, what the...... and instrumental orchestrations have potential shortcomings since the technologies that currently exist in school contexts are rather different from the technologies instrumental genesis was originally developed to study.......This paper investigates the origins of the instrumental genesis and instrumental orchestrations frameworks. This is done by reviewing instrumented activity situations, instrumental genesis, and instrumental orchestrations with the purpose of identifying their epistemological assumptions, what...

  18. Slip rate and tremor genesis in Cascadia

    Science.gov (United States)

    Wech, Aaron G.; Bartlow, Noel M.

    2014-01-01

    At many plate boundaries, conditions in the transition zone between seismogenic and stable slip produce slow earthquakes. In the Cascadia subduction zone, these events are consistently observed as slow, aseismic slip on the plate interface accompanied by persistent tectonic tremor. However, not all slow slip at other plate boundaries coincides spatially and temporally with tremor, leaving the physics of tremor genesis poorly understood. Here we analyze seismic, geodetic, and strainmeter data in Cascadia to observe for the first time a large, tremor-generating slow earthquake change from tremor-genic to silent and back again. The tremor falls silent at reduced slip speeds when the migrating slip front pauses as it loads the stronger adjacent fault segment to failure. The finding suggests that rheology and slip-speed-regulated stressing rate control tremor genesis, and the same section of fault can slip both with and without detectable tremor, limiting tremor's use as a proxy for slip.

  19. The genesis of collective health in Brazil.

    Science.gov (United States)

    Vieira-da-Silva, Ligia Maria; Pinell, Patrice

    2014-03-01

    During the 1970s in Brazil a social space directed towards health problems on the population level, called collective health, was created and institutionalised. To what extent did this Brazilian invention correspond to a specific socio-historical practice? The works published on this topic have considered social medicine as a homogeneous phenomenon without empirically studying the specificities of national experiences. To bridge this gap, a historical study on the genesis of collective health in Brazil was carried out based on Bourdieu's field theory. The interaction between the paths of the founders and the conditions of historical possibilities were researched through documentary and bibliographical sources, as well as through in-depth interviews of the founders. This social space originated from a meeting of agents with different social backgrounds but who interconnected, creating a structure that was independent of each agent considered individually. One of the components of this establishment was the joining of theoretical production and the implementation of health reforms that resulted in the organisation of a universal health system. This study attempts to show how the international political situation and the contradictions of the national crisis created a universe of possibilities, allowing for the genesis of this sui generis space in Brazil. © 2013 The Authors. Sociology of Health & Illness © 2013 Foundation for the Sociology of Health & Illness/John Wiley & Sons Ltd.

  20. Genesis Eco Systems, Inc. soil washing process

    International Nuclear Information System (INIS)

    Cena, R.J.

    1994-01-01

    The Genesis soil washing system is an integrated system of modular design allowing for maximum material handling capabilities, with optimized use of space for site mobility. The Surfactant Activated Bio-enhanced Remediation Equipment-Generation 1 (SABRE-1, Patent Applied For) modification was developed specifically for removing petroleum byproducts from contaminated soils. Scientifically formulated surfactants, introduced by high pressure spray nozzles, displace the contaminant from the surface of the soil particles into the process solution. Once the contaminant is dispersed into the liquid fraction of the process, it is either mechanically removed, chemically oxidized, or biologically oxidized. The contaminated process water is pumped through the Genesis Biosep (Patent Applied For) filtration system where the fines portion is flocculated, and the contaminant-rich liquid portion is combined with an activated mixture of nutrients and carefully selected bacteria to decompose the hydrocarbon fraction. The treated soil and dewatered fines are transferred to a bermed stockpile where bioremediation continues during drying. The process water is reclaimed, filtered, and recycled within the system

  1. Genesis of cluster associations of enterprises

    Directory of Open Access Journals (Sweden)

    Pulina Tetyana V.

    2013-03-01

    Full Text Available The goal of the article is the study of genesis of creation of cluster associations of enterprises. It considers genesis of cluster definitions. It shows and analyses components that define the “cluster” concept. Researchers from many countries offer a significant number of definitions of the “cluster” term specifically in the economic direction, but there is no single generally accepted definition as of today. This fact is the result of a significant diversity of cluster structures. The article conducts a comparative analysis of classifications of cluster associations of enterprises. It identifies advantages and shortcomings of the cluster approach both from the position of an enterprise and from the position of a regional economy administration. The article marks out specific features of the life cycle of cluster associations of enterprises, which consists of the preparatory stage and stage of commercialisation. Majority of studies consider the preparatory stage and the stage of commercialisation, which consists of the following stages: entering market with a common brand, growth, maturity and crisis – is, practically, not considered. Taking into account the fact that the main result of cluster activity is the synergetic effect from mutually beneficial co-operation and activity results facilitate ensuring competitiveness of cluster enterprises, regional and national economies, the author gives own definition of a cluster.

  2. Discussion on the genesis of Zhongchuan uranium deposit

    International Nuclear Information System (INIS)

    Zhang Yulong; Zhang Chengzhong

    2008-01-01

    Through elaborating the geological setting, deposit and orebody geological charactors and hydrological features, the ore controlling factors are analysed and the genesis of Zhongchuan uranium deposit is discussed in the way of deposit occurrence, mineral asembleage and matalization ages. It is believed that uranium deposit was formed under the regional uplifting background with the exogenous mechanism and its genesis belongs to surface leaching. (authors)

  3. Genesis Science Team Report on Mission Status

    Science.gov (United States)

    Burnett, D. S.

    2005-12-01

    The Genesis Discovery Mission exposed pure materials to the solar wind at the L1 Lagrangian point for 27 months between December 2001 and April 2004. These were returned for analysis in terrestrial laboratories in Sept 2004. The general science objectives for Genesis are: (1) measure solar isotopic abundance ratios to the precision required for planetary science problems, (2) improve the accuracy of photospheric elemental abundances by a least a factor of three, (3) provide independent analyses of the 3 major solar wind regimes and (4) provide a reservoir of solar matter for subsequent studies. Based on these general objectives, we are working towards a list of 18 specific prioritized measurement objectives, the first 5 of which are isotopic measurements. The two highest priority objectives are the isotopic compositions of O and N; to obtain a higher signal to background ratio for these elements, a concentrator (focusing ion telescope) was built at LANL to provide a factor of 20 fluence enhancement for elements lighter than P on a 30 mm radius target. The concentrator performed well in flight. A variety of other collector materials, tailored to specific analytical approaches, were mounted in 5 arrays of 55 hexagons, 4 cm point to point. Three of the arrays were used to provide the independent regime (coronal hole, low speed interstream, and coronal mass ejection) samples. The solar wind regime was measured by LANL Solar Wind Monitors on the Genesis spacecraft and the appropriate array exposed while the inappropriate array remained shielded. Array switchouts were carried out flawlessly during flight. Sample analyses have been slowed considerably by a parachute deployment failure which caused a crash of the sample return capsule upon reentry and by the presence of an in-flight contamination film, affectionately referred to as the brown stain. The crash has led to major loss of collector materials, along with significant pitting and scratching of the surviving

  4. The genesis and evolution of the African Field Epidemiology Network

    African Journals Online (AJOL)

    The genesis and evolution of the African Field Epidemiology Network. David Mukanga, Mufuta Tshimanga, Frederick Wurapa, David Serwada, George Pariyo, Fred Wabwire-Mangen, Sheba Gitta, Stella Chungong, Murray Trostle, Peter Nsubuga ...

  5. 192 RE-INTERPRETING GENESIS 34 IN THE LIGHT OF ...

    African Journals Online (AJOL)

    User

    notoriety as one of the prime security challenges confronting the country. Genesis .... thing has been done to them by Shechem. ... The use of the word חַטֶבּ which means security ..... students and internet writers; and the polylectic approach.

  6. Genesis of natural cokes: Some Indian examples

    Energy Technology Data Exchange (ETDEWEB)

    Singh, Ashok K.; Sharma, Mamta [Central Institute of Mining and Fuel Research, Dhanbad, PIN-828108 (India); Singh, Mahendra P. [Banaras Hindu University, Varanasi, PIN-221005 (India)

    2008-06-13

    In Indian coalfields huge amounts of natural coke have been produced due to magmatic intrusions. Jharia Coalfield in eastern part of India alone contains approximately 2000 Mt of baked coking coal as a consequence of these intrusions in the form of discordant and concordant bodies. This paper is an effort to investigate the effect of carbonization in two intrusion affected coal seams of Ena (seam XIII) and Alkusa (seam XIV) collieries of Jharia Coalfield. Natural coke is derived from coking coal under in-situ conditions due to intense magmatic induced heat and overburden pressure. Natural coke is characterized by the presence of low volatile matter and high ash contents and organic constituents showing isotropy and anisotropy. Through physical, petrographic and chemical properties of natural coke or 'jhama' as determined by various methods it has been established that the reactives in the unaltered coals (vitrinite, liptinite, pseudovitrinite, reactive semifusinite, etc.) are < 25.0 vol.%, moisture < 2.5%, volatile matter < 15.0% and hydrogen < 4.0%. The temperatures attained in the coal seams have been deciphered using some standard models, which indicate that a temperature {proportional_to} 1000 C was attained. This produced huge amount of anisotropic and deposited carbons. An attempt has been made to understand the factors that influence the genesis of natural coke and heat altered maceral products in coals in Indian coalfields. (author)

  7. Genesis and Evolution of Interfaces in Product Architecture

    DEFF Research Database (Denmark)

    Donmez, Mehmet; Hsuan, Juliana

    Interfaces are elements of the product architecture that facilitates innovation and enables an organization to leverage the trade-off between cost and performance of its products. Despite the importance of interfaces for organizations, little is known about their genesis and evolution. In this st......Interfaces are elements of the product architecture that facilitates innovation and enables an organization to leverage the trade-off between cost and performance of its products. Despite the importance of interfaces for organizations, little is known about their genesis and evolution...

  8. On the genesis of the uraniferous deposits I

    International Nuclear Information System (INIS)

    Mingarro, E.

    1964-01-01

    The main problems of the genesis of uranium deposits as hydro thermals are objectively considered here under three aspects: uranium source transport and deposition. The transport of uranium can be effected under a tetravalent form, or as complex ions of hexavalent uranium: as uranyl ion (UO 2 ) 2 + or under complex carbonic or sulfuric forms, such as UO 2 (XO n ) 2 2 - or UO 2 (XO n ) 3 4 -. These three ways of transport correspond to the three basic geochemical para genesis of uranium: uranium-titanium, uranium-cobalt, uranium. Deposition is currently made by reduction and in some way is no dependent of mineralogical association. (Author) 61 refs

  9. Pristine Igneous Rocks and the Genesis of Early Planetary Crusts

    Science.gov (United States)

    Warren, Paul H.; Lindstrom, David (Technical Monitor)

    2002-01-01

    Our studies are highly interdisciplinary, but are focused on the processes and products of early planetary and asteroidal differentiation, especially the genesis of the ancient lunar crust. The compositional diversity that we explore is the residue of process diversity, which has strong relevance for comparative planetology.

  10. Tropical Cyclone Genesis Efficiency: Mid-Level Versus Bottom Vortex

    Science.gov (United States)

    2011-12-16

    storm strength). Figure 4b shows the time evolutions of the corresponding maximum surface wind speed from the four experiments. Based on the definition...Pacific during summer. Mon. Wea. Rev., 124, 2245–2266. Chen, S. S. and W. M. Frank, 1993: A numerical study of the genesis of extratropical convective

  11. Nursing perspective on the Genesis account of creation.

    Science.gov (United States)

    Geary, Heidi D; Cone, Pamela H

    2012-01-01

    Biblical accounts of creation tell the origin of the world and the beginning of God's relationship with humankind. Azusa Pacific University assigns graduate nursing students a faith integration project analyzing Creation accounts through the eyes of a nurse researcher. This report integrates eight students' investigations of Genesis 1 and 2, offering deep, rich insight into nursing practice.

  12. Python as a federation tool for GENESIS 3.0.

    Directory of Open Access Journals (Sweden)

    Hugo Cornelis

    Full Text Available The GENESIS simulation platform was one of the first broad-scale modeling systems in computational biology to encourage modelers to develop and share model features and components. Supported by a large developer community, it participated in innovative simulator technologies such as benchmarking, parallelization, and declarative model specification and was the first neural simulator to define bindings for the Python scripting language. An important feature of the latest version of GENESIS is that it decomposes into self-contained software components complying with the Computational Biology Initiative federated software architecture. This architecture allows separate scripting bindings to be defined for different necessary components of the simulator, e.g., the mathematical solvers and graphical user interface. Python is a scripting language that provides rich sets of freely available open source libraries. With clean dynamic object-oriented designs, they produce highly readable code and are widely employed in specialized areas of software component integration. We employ a simplified wrapper and interface generator to examine an application programming interface and make it available to a given scripting language. This allows independent software components to be 'glued' together and connected to external libraries and applications from user-defined Python or Perl scripts. We illustrate our approach with three examples of Python scripting. (1 Generate and run a simple single-compartment model neuron connected to a stand-alone mathematical solver. (2 Interface a mathematical solver with GENESIS 3.0 to explore a neuron morphology from either an interactive command-line or graphical user interface. (3 Apply scripting bindings to connect the GENESIS 3.0 simulator to external graphical libraries and an open source three dimensional content creation suite that supports visualization of models based on electron microscopy and their conversion to

  13. Python as a federation tool for GENESIS 3.0.

    Science.gov (United States)

    Cornelis, Hugo; Rodriguez, Armando L; Coop, Allan D; Bower, James M

    2012-01-01

    The GENESIS simulation platform was one of the first broad-scale modeling systems in computational biology to encourage modelers to develop and share model features and components. Supported by a large developer community, it participated in innovative simulator technologies such as benchmarking, parallelization, and declarative model specification and was the first neural simulator to define bindings for the Python scripting language. An important feature of the latest version of GENESIS is that it decomposes into self-contained software components complying with the Computational Biology Initiative federated software architecture. This architecture allows separate scripting bindings to be defined for different necessary components of the simulator, e.g., the mathematical solvers and graphical user interface. Python is a scripting language that provides rich sets of freely available open source libraries. With clean dynamic object-oriented designs, they produce highly readable code and are widely employed in specialized areas of software component integration. We employ a simplified wrapper and interface generator to examine an application programming interface and make it available to a given scripting language. This allows independent software components to be 'glued' together and connected to external libraries and applications from user-defined Python or Perl scripts. We illustrate our approach with three examples of Python scripting. (1) Generate and run a simple single-compartment model neuron connected to a stand-alone mathematical solver. (2) Interface a mathematical solver with GENESIS 3.0 to explore a neuron morphology from either an interactive command-line or graphical user interface. (3) Apply scripting bindings to connect the GENESIS 3.0 simulator to external graphical libraries and an open source three dimensional content creation suite that supports visualization of models based on electron microscopy and their conversion to computational models

  14. Folk narratives structures in Genesis 2, 4 -3, 24

    Directory of Open Access Journals (Sweden)

    Magdalena Flores Ferres

    2015-04-01

    Full Text Available The objective of this research is to demonstrate that Genesis 2.4 to 3.24, can be considered, from the perspective of the structure, a traditional folk story, since it contains the morphologic elements of this type of literature. To that end, in this paper we focus on the study of the structure of the folk tale. The structure of the action sequence of such tales is interesting from differente disciplines, due to its remarkable stability. To that end, we will review the postulates proposed by Vladimir Propp in his book “Morphology of the Folktale” (1928. From these theoretical foundations, we conducted a contrastive analysis of the Genesis 2.4 to 3.24, in paralell to the russian folktale “The Cat, the Rooster and the Fox” (Afanasiev, 1981, after which it was found that both tales have the same narrative structure.

  15. Safety analysis of a pool Genesis II irradiator

    International Nuclear Information System (INIS)

    Rodrigues Junior, Ary de A.

    2011-01-01

    The Genesis II Irradiator manufactured by GRAT * STAR Inc. (USA) is a category III gamma irradiator in which the sealed source is contained in a water filled storage pool and is shielded permanently, i.e. the material has to move down to the source. Even though the pool is 5.6 m deep, what would happen if the water level lowered? There are a series of safety devices that will avoid this situation and calculations show that the water level has to be very low in order to deliver a significant dose; moreover, only in case a person remains at the border of the pool for a long time this would be risky. In conclusion, it is practically impossible for someone to be exposed to radiation from a Genesis II Irradiator source. (author)

  16. Augustine on redemption in Genesis 1�3

    Directory of Open Access Journals (Sweden)

    Edward L. Smither

    2014-01-01

    Full Text Available Many theologians, including those concerned with theology of mission, frame the dramaof God�s story and mission (missio Dei through the three major acts of creation, fall andredemption. Others add that the new creation ought to be regarded as a fourth act. Althoughthis framework describes the entire biblical narrative, creation, fall and the hope of redemptionare, of course, quite present in the first three chapters of Genesis. In this article, I endeavouredto engage with the commentaries of the African church father Augustine of Hippo (354�430 CE to grasp his thoughts on redemption in Genesis 1�3. In his Genesis works, Augustinewas primarily concerned with clarifying the doctrine of creation and, relatively speaking, hadfar less to say about redemption. That said, Augustine was, quite interested with Scripture�sstory of redemption in his magnum opus De Civitate Dei [City of God]. Thus, in this article, Iexplored two major questions: firstly, why did Augustine pay so little attention to redemptionin Genesis 1�3? Secondly, how did he articulate and relate redemption in these chapters? Itwas shown that whilst his primary focus was to articulate creation, his thoughts on redemptionwere probably limited some because of the insufficiency of his Old Latin Bible translation andperhaps because of other distractions in ministry. Furthermore, it was argued that Augustine�sdoctrine of redemption was a subset of his discussion on creation � specifically, that the secondAdam (Christ brought new life to God�s image bearers affected by the fall of the first Adam.Intradisciplinary and/or interdisciplinary implications: My aim was to establish Augustine�sthoughts on redemption as a point of dialogue for theologians of mission endeavouring toclarify a theology of mission. As most mission theologians do not consult Augustine in theirwork and as most early Christian scholars do not read Augustine missionally, this studyoffered fresh insights for

  17. Education in the Knowledge Society: Genesis of Concept and Reality

    Science.gov (United States)

    Karpov, Alexander O.

    2016-01-01

    The aim of the article is to define the content of theoretical ideas about education in the knowledge society in terms of the birth of its social reality. It is shown that the genesis of the concept of education in the knowledge society goes back to the period of 1950-1960s and is due to the emergence of new qualities of an industrial worker that…

  18. GENESIS OF METHODOLOGY OF MANAGEMENT BY DEVELOPMENT OF ORGANIZATIONS

    Directory of Open Access Journals (Sweden)

    Z.N. Varlamova

    2007-06-01

    Full Text Available In clause the genesis of methodology of management of development of organizations as sets of the used methodological approaches and methods is investigated. The results of the comparative analysis of the methodological approaches to management of organizational development are submitted. The traditional methodological approaches are complemented strategic experiment and methodology case studies. The approaches to formation of new methodology and technique of research of sources of competitive advantages of organization are considered.

  19. Evolution of the marketing theory: genesis, conception, periodization

    OpenAIRE

    M.A. Oklander; T.O. Oklander

    2016-01-01

    The aim of this article. The article deals with evolution of the marketing theory in it genesis context, modern conception, periodization. Mercantilism, classical and neoclassical political economy, marginalism, institutionalism are distinguished as scientific sources of marketing. One defines that modern marketing conception is a socially responsible marketing form, based on mass individualization, the highest customer value supply, consumer’s problems effective solving. The marketing theory...

  20. On the genesis of the uraniferous deposits I; Consideraciones sobre la genesis de los yacimientos uraniferos. I.

    Energy Technology Data Exchange (ETDEWEB)

    Mingarro, E

    1964-07-01

    The main problems of the genesis of uranium deposits as hydro thermals are objectively considered here under three aspects: uranium source transport and deposition. The transport of uranium can be effected under a tetravalent form, or as complex ions of hexavalent uranium: as uranyl ion (UO{sub 2}){sup 2}+ or under complex carbonic or sulfuric forms, such as UO{sub 2}(XO{sub n}){sub 2}{sup 2}- or UO{sub 2}(XO{sub n}){sub 3}{sup 4}-. These three ways of transport correspond to the three basic geochemical para genesis of uranium: uranium-titanium, uranium-cobalt, uranium. Deposition is currently made by reduction and in some way is no dependent of mineralogical association. (Author) 61 refs.

  1. Towards a Statistical Model of Tropical Cyclone Genesis

    Science.gov (United States)

    Fernandez, A.; Kashinath, K.; McAuliffe, J.; Prabhat, M.; Stark, P. B.; Wehner, M. F.

    2017-12-01

    Tropical Cyclones (TCs) are important extreme weather phenomena that have a strong impact on humans. TC forecasts are largely based on global numerical models that produce TC-like features. Aspects of Tropical Cyclones such as their formation/genesis, evolution, intensification and dissipation over land are important and challenging problems in climate science. This study investigates the environmental conditions associated with Tropical Cyclone Genesis (TCG) by testing how accurately a statistical model can predict TCG in the CAM5.1 climate model. TCG events are defined using TECA software @inproceedings{Prabhat2015teca, title={TECA: Petascale Pattern Recognition for Climate Science}, author={Prabhat and Byna, Surendra and Vishwanath, Venkatram and Dart, Eli and Wehner, Michael and Collins, William D}, booktitle={Computer Analysis of Images and Patterns}, pages={426-436}, year={2015}, organization={Springer}} to extract TC trajectories from CAM5.1. L1-regularized logistic regression (L1LR) is applied to the CAM5.1 output. The predictions have nearly perfect accuracy for data not associated with TC tracks and high accuracy differentiating between high vorticity and low vorticity systems. The model's active variables largely correspond to current hypotheses about important factors for TCG, such as wind field patterns and local pressure minima, and suggests new routes for investigation. Furthermore, our model's predictions of TC activity are competitive with the output of an instantaneous version of Emanuel and Nolan's Genesis Potential Index (GPI) @inproceedings{eman04, title = "Tropical cyclone activity and the global climate system", author = "Kerry Emanuel and Nolan, {David S.}", year = "2004", pages = "240-241", booktitle = "26th Conference on Hurricanes and Tropical Meteorology"}.

  2. Luther's Lectures on Genesis 1:26-2:3

    DEFF Research Database (Denmark)

    Pedersen, Else Marie Wiberg

    2017-01-01

    This is a revised translation of Luther's Lectures on Genesis 1:26-2:3 (1535), drawn from Luther's Works, vol. 1, 55-82, but based on the Latin version of WA 42, 41-62. This revised translation is done with regard to inclusive language, and in this respect much closer to the Latin origin than...... to the English of the LW. I have added completely new annotations to explain Luther's theology as well as contetualize it, and chiefly new footnotes to explain the language and translations made....

  3. Can micro-PIXE measurements help to determine ore genesis ?

    International Nuclear Information System (INIS)

    Ahmed, M.; Al-Ohali, M.A.

    2002-01-01

    This study is an attempt to demonstrate how the nuclear micro-PIXE technique can be utilized to investigate ore genesis of geological deposits. Elemental concentrations and distribution profiles in single mineral grains and matrices in a present-day ore deposit on land were measured using the scanning proton microprobe on the 3 MV Tandetron accelerator at King Fahd University of Petroleum and Minerals. Comparing the distribution profiles of some of the trace elements detected it was possible to suggest an organic, sea origin of these deposits. (Author)

  4. Lectures on Genesis 1:26-2:3 and 2:21-25

    DEFF Research Database (Denmark)

    Stjerna, Kirsi; Pedersen, Else Marie Wiberg

    2017-01-01

    This introduction to parts of Luther's lectures on Genesis (1535-45), namely his lectures on Genesis 1:26-2:3 and 2:21-25, discusses the reformer's grappling with the text in its historical and theological context. Not least is the question of gender taken under scrutiny, as the two authors, Kirsi...

  5. 75 FR 69458 - Notice of Availability of the Record of Decision for the Genesis Solar Energy Project and...

    Science.gov (United States)

    2010-11-12

    ..., LVRWB09B2520] Notice of Availability of the Record of Decision for the Genesis Solar Energy Project [email protected] . SUPPLEMENTARY INFORMATION: Genesis Solar, LLC, a wholly owned subsidiary of NextEra Energy Resources, filed right-of-way (ROW) application CACA-048880 for the proposed Genesis Solar Energy...

  6. Multi-element RIMS Analysis of Genesis Solar Wind Collectors

    Science.gov (United States)

    Veryovkin, I. V.; Tripa, C. E.; Zinovev, A. V.; King, B. V.; Pellin, M. J.; Burnett, D. S.

    2009-12-01

    The samples of Solar Wind (SW) delivered by the NASA Genesis mission, present significant challenges for surface analytical techniques, in part due to severe terrestrial contamination of the samples on reentry, in part due to the ultra-shallow and diffused ion implants in the SW collector materials. We are performing measurements of metallic elements in the Genesis collectors using Resonance Ionization Mass Spectrometry (RIMS), an ultra-sensitive analytical method capable of detecting SW in samples with lateral dimensions of only a few mm and at concentrations from above one ppm to below one ppt. Since our last report at 2008 AGU Fall Meeting, we have (a) developed and tested new resonance ionization schemes permitting simultaneous measurements of up to three (Ca, Cr, and Mg) elements, and (b) improved reproducibility and accuracy of our RIMS analyses for SW-like samples (i.e. shallow ion implants) by developing and implementing an optimized set of new analytical protocols. This is important since the quality of scientific results from the Genesis mission critically depends on the accuracy of analytical techniques. In this work, we report on simultaneous RIMS measurements of Ca and Cr performed on two silicon SW collector samples, (#60179 and #60476). First, we have conducted test experiments with 3×1013 at/cm2 52Cr and 44Ca implants in silicon to evaluate the accuracy of our quantitative analyses. Implant fluencies were measured by RIMS to be 2.73×1013 and 2.71×1013 at/cm2 for 52Cr and 44Ca, respectively, which corresponds to an accuracy of ≈10%. Using the same implanted wafer as a reference, we conducted RIMS analyses of the Genesis samples: 3 spots on #60179 and 4 spots on #60476. The elemental SW fluencies expected for Cr and Ca are 2.95×1010 and 1.33×1011 at/cm2 , respectively. Our measurements of 52Cr yielded 3.0±0.6×1011 at/cm2 and 5.1±4.1×1010 at/cm2 for #60179 and #60476, respectively. For 40Ca, SW fluencies of 1.39±0.70×1011 at/cm2 in #60179

  7. Genesis of the Brazilian nuclear power plants program

    International Nuclear Information System (INIS)

    Syllus, G.; Lepecki, W.

    1996-01-01

    The genesis of the Brazilian Nuclear Power Program is described by the authors - who participated in the events - from the beginning of the sixties, until the definition and the start of the implementation in 1975 of the Reference Nuclear Power Program. A description is made of the main events, studies and decisions that contributed to the evolution of the Program: the GTRP (Nuclear Power Plant Working Group); the Thorium Group; the Lane Group; the decision about Angra 1; CNEN's analyses about the reactor line and, finally, the creation of CBTN (Nuclear Technology Brazilian Company), which elaborated the studies that resulted in the final definition of the Program and led to the Brazilian German Agreement and the establishment of NUCLEBRAS. (author)

  8. Characteristics and genesis of porphyroclastic lava rock in Xiangshan

    International Nuclear Information System (INIS)

    Zhou Xiaohua; Wang Zhuning

    2012-01-01

    Due to the transitional characteristics of porphyroclastic lava rock in Xiangshan of Jiangxi province, there are a variety of views on its genesis, petrographic attribution. This is because the marginal facies of the porphyroclastic lava is with ignimbrite and tuff characteristics, its transition phase has the characteristics of lava, and its intermediate phase has the feature of sub-volcanic rocks, further more, different texture of the rocks bears transition relationship. By the study of mineral composition, REE pattern, trace elements, isotopes, we put forward that the porphyroclastic lava is formed by the remelting of basement metamorphic rocks. The rocks was believed to be formed in the environment similar to volcanics and subvolcanics, and quite different to plutonic rocks due to the features of low-structure of potassium feldspar phenocrysts and solution mechanism, because the porphyroclastic lava phenocrysts occurs as fragments and maybe related to cryptoexplosion. Therefore the rocks was believed to belong to the volcano extrusive facies. (authors)

  9. A theory of the genesis of breast duct papilloma.

    Science.gov (United States)

    WHANG, J

    1960-03-01

    While it is not the intent to argue that papilloma never develops in the conventionally accepted manner (proliferative growth from the wall of a pre-existing cavity) a new, perhaps alternative, genesis is suggested. The concept is that, beginning with the usual lobular structure of the breast, first by hyperplasia and then by coalescence of alveoli, seen earliest at the periphery of the lobule, spaces appear between the content of the lobule and the wall. By confluence of these spaces a larger cystic cavity is formed. Coalescence of alveoli through the body of the central mass, in the same way as at the periphery, develops the familiar pattern of "papilloma." Following the earlier hyperplasia, regressive changes appear and may go on to complete disintegration of the papillary mass, leaving a smooth-walled cavity.

  10. GENESI-DR Portal: a scientific gateway to distributed repositories

    Science.gov (United States)

    Goncalves, Pedro; Brito, Fabrice; D'Andria, Fabio; Cossu, Roberto; Fusco, Luigi

    2010-05-01

    GENESI-DR (Ground European Network for Earth Science Interoperations - Digital Repositories) is a European Commission (EC)-funded project, kicked-off early 2008 lead by ESA; partners include Space Agencies (DLR, ASI, CNES), both space and no-space data providers such as ENEA (I), Infoterra (UK), K-SAT (N), NILU (N), JRC (EU) and industry as Elsag Datamat (I), CS (F) and TERRADUE (I). GENESI-DR intends to meet the challenge of facilitating "time to science" from different Earth Science disciplines in discovery, access and use (combining, integrating, processing, …) of historical and recent Earth-related data from space, airborne and in-situ sensors, which are archived in large distributed repositories. "Discovering" which data are available on a "geospatial web" is one of the main challenges ES scientists have to face today. Some well- known data sets are referred to in many places, available from many sources. For core information with a common purpose many copies are distributed, e.g., VMap0, Landsat, and SRTM. Other data sets in low or local demand may only be found in a few places and niche communities. Relevant services, results of analysis, applications and tools are accessible in a very scattered and uncoordinated way, often through individual initiatives from Earth Observation mission operators, scientific institutes dealing with ground measurements, service companies or data catalogues. In the discourse of Spatial Data Infrastructures, there are "catalogue services" - directories containing information on where spatial data and services can be found. For metadata "records" describing spatial data and services, there are "registries". The Geospatial industry coins specifications for search interfaces, where it might do better to reach out to other information retrieval and Internet communities. These considerations are the basis for the GENESI-DR scientific portal, which adopts a simple model allowing the geo-spatial classification and discovery of

  11. A Region-Based GeneSIS Segmentation Algorithm for the Classification of Remotely Sensed Images

    Directory of Open Access Journals (Sweden)

    Stelios K. Mylonas

    2015-03-01

    Full Text Available This paper proposes an object-based segmentation/classification scheme for remotely sensed images, based on a novel variant of the recently proposed Genetic Sequential Image Segmentation (GeneSIS algorithm. GeneSIS segments the image in an iterative manner, whereby at each iteration a single object is extracted via a genetic-based object extraction algorithm. Contrary to the previous pixel-based GeneSIS where the candidate objects to be extracted were evaluated through the fuzzy content of their included pixels, in the newly developed region-based GeneSIS algorithm, a watershed-driven fine segmentation map is initially obtained from the original image, which serves as the basis for the forthcoming GeneSIS segmentation. Furthermore, in order to enhance the spatial search capabilities, we introduce a more descriptive encoding scheme in the object extraction algorithm, where the structural search modules are represented by polygonal shapes. Our objectives in the new framework are posed as follows: enhance the flexibility of the algorithm in extracting more flexible object shapes, assure high level classification accuracies, and reduce the execution time of the segmentation, while at the same time preserving all the inherent attributes of the GeneSIS approach. Finally, exploiting the inherent attribute of GeneSIS to produce multiple segmentations, we also propose two segmentation fusion schemes that operate on the ensemble of segmentations generated by GeneSIS. Our approaches are tested on an urban and two agricultural images. The results show that region-based GeneSIS has considerably lower computational demands compared to the pixel-based one. Furthermore, the suggested methods achieve higher classification accuracies and good segmentation maps compared to a series of existing algorithms.

  12. Shallow gas charged sediments off the Indian west coast: Genesis and distribution

    Digital Repository Service at National Institute of Oceanography (India)

    Mazumdar, A.; Peketi, A.; Dewangan, P.; Badesab, F.K.; Ramprasad, T; Ramana, M.V.; Patil, D.J.; Dayal, A.M.

    Geophysical and geochemical surveys were carried out off Goa, central west coast of India, to understand the genesis and distribution of shallow gases in marine sediments. Shallow gas charged sediments within the water depths of approx. 15 to 40 m...

  13. Post-Disaster Image Processing for Damage Analysis Using GENESI-DR, WPS and Grid Computing

    OpenAIRE

    Bielski, Conrad; Gentilini, Simone; Pappalardo, Marco

    2011-01-01

    The goal of the two year Ground European Network for Earth Science Interoperations-Digital Repositories (GENESI-DR) project was to build an open and seamless access service to Earth science digital repositories for European and world-wide science users. In order to showcase GENESI-DR, one of the developed technology demonstrators focused on fast search, discovery, and access to remotely sensed imagery in the context of post-disaster building damage assessment. This paper descri...

  14. Maternal perceptions of their child's weight status: the GENESIS study.

    Science.gov (United States)

    Manios, Yannis; Kondaki, Katerina; Kourlaba, Georgia; Vasilopoulou, Emilia; Grammatikaki, Evangelia

    2009-08-01

    The objective of the present work was to quantify mothers' misclassification of pre-school children's weight status and to determine factors associated with the maternal misperception. A representative sample of 2287 children aged 2-5 years was examined (GENESIS study). Mothers' perceptions of their child's weight status and the children's and mothers' anthropometric and other characteristics (sociodemographic and lifestyle) were recorded. Almost 38 % of mothers underestimated their child's weight status. The frequency of underestimation was much higher among 'at risk of being overweight' and 'overweight' children (88.3 % and 54.5 %, respectively) compared with 'underweight/normal-weight' children (18.0 %, P engaging in physical activity for less than 3 h/week and in children whose mothers had low education status, compared with their counterparts. Moreover, the higher the BMI-for-age Z-score, the greater the odds that the mother would underestimate her child's weight status. The current study demonstrated that more than one-third of mothers misclassify their children's weight status as being lower than the actual. Given that mother's weight perception might be an important determinant of child's body weight development, clinicians and health professionals should help mothers correctly classify their children's weight status, which could potentially help in the early prevention of overweight and obesity.

  15. REE geochemistry and genesis of Daxin uranium deposit

    International Nuclear Information System (INIS)

    Li Zhixing; Qi Fucheng; He Zhongbo; Zhang Zilong

    2011-01-01

    Through the analysis on typical REE parameters,chondrite-normalized REE patterns and hierarchical cluster analysis of rocks in the structural-geochemical zonation in Daxin uranium deposit, the paper discusses the uranium source and genesis. The study shows that the uranium source mainly came from Cambrian System. The Devonian System is maily as the favorable room for saving ores in addition to pre-concentrated room for uranium. Underground water resulted from early and late Yanshanian movement and the heating of volcanic rock was turned into geothermal water and it was moved upward by the force of tectonic movement. The geothermal water mainly extracted active uranium from the Cambrian rocks, then moved upward along main regional fault (F2) connecting the Cambrian rocks and the Devonian rocks until it arrived in structural fracture zone which was controlled by secondary faults (F13, F23, F33). At last, the uranium element in geothermal water was precipitated and concentrated into the uranium deposit in reducing environment of enriched organic material and pyrite. (authors)

  16. GENESIS - The GENEric SImulation System for Modelling State Transitions.

    Science.gov (United States)

    Gillman, Matthew S

    2017-09-20

    This software implements a discrete time Markov chain model, used to model transitions between states when the transition probabilities are known a priori . It is highly configurable; the user supplies two text files, a "state transition table" and a "config file", to the Perl script genesis.pl. Given the content of these files, the script generates a set of C++ classes based on the State design pattern, and a main program, which can then be compiled and run. The C++ code generated is based on the specification in the text files. Both multiple branching and bi-directional transitions are allowed. The software has been used to model the natural histories of colorectal cancer in Mexico. Although written primarily to model such disease processes, it can be used in any process which depends on discrete states with known transition probabilities between those states. One suitable area may be in environmental modelling. A test suite is supplied with the distribution. Due to its high degree of configurability and flexibility, this software has good re-use potential. It is stored on the Figshare repository.

  17. The genesis of WiFi and its applications

    CERN Multimedia

    CERN. Geneva

    2008-01-01

    In 1985 changes to US regulations caused a paradigm shift by permitting the use of radio spectrum for devices that did not need to have an end-user license. After a few years, products appeared on the market and a group developed a standard for broadband wireless communications among computers. The presentation will explain how the standard developed and was adopted by the Wi-Fi Alliance, as well as the global harmonization and expansion of the available radio spectrum to over half a GHz. The success of Wi-Fi and user innovation and initiatives makes it a vehicle to bring broadband internet to rural areas both in developing as well as in developed countries. Vic Hayes is a Senior Research Fellow at the Delft University of Technology and is writing a book titled "The genesis of Wi-Fi and the road toward global success". He holds a BSEE and joined NCR in the Netherlands in 1974. He co-established and chaired the IEEE 802.11 Standards Working Group for Wireless Local Area Networks and became known as the "Fathe...

  18. GENESIS CONTRADICTIONS OF GENDER APPROACH IN EDUCATION OF CHILDREN

    Directory of Open Access Journals (Sweden)

    Zh. N. Dyuldina

    2016-01-01

    Full Text Available The aim of the investigation is to consider genesis contradictions of gender approach in modern education and training of children and possibilities of its application in an educational system during the newest period of the society development.Methods, results and scientific novelty. The retrospective analysis of the sources has shown that gender approach isn’t new and not studied: on the contrary, separate education and training of boys and girls in the past was a norm and a duty of parents and teachers. However, the reflection of social processes shows the demolition of traditional system of gender stratification; weakening of women’s and men’s polarization of social roles; change of cultural stereotypes of masculinity and femininity; objective changes in the matrimonial relations. Everything listed above brings into focus an investigative search of new approaches to gender education. The essence of the terms «gender», «gender approach» is specified. Despite very long history of gender education (which was cultivated since the most ancient eras of existence of a mankind, insufficient study of this problem is stated now. Special importance of gender aspect in family education is emphasized. The different points of view in understanding of gender approach in modern science are revealed; the main perspective directions of researches on this subject are noted.Practical significance. The materials of the present article can be used in teaching history of pedagogics, gender psychology and gender pedagogics.

  19. The genesis of fluid mechanics, 1640-1780

    CERN Document Server

    Calero, Julián Simón

    2008-01-01

    Fluid Mechanics, as a scientific discipline in a modern sense, was established between the last third of the 17th century and the first half of the 18th one. This book analyses its genesis, following its evolution along two basic lines of research, which have been named the "problem of resistance" and the "problem of discharge". This approach highlights the existence of a remarkable experimental aspect in the aforementioned research lines, together with their link with problems of a practical nature, such as ballistics, hydraulics, fluid-using machines or naval theory. On the other hand, although previous studies usually present fluid mechanics from the point of view of mathematics, this is complemented here by an engineering viewpoint; gathering attempts made in the beginnings of fluid mechanics to see if the theory was capable of productive application in practical terms. This is nothing unusual in a time where the quality of knowledge and skill is measured largely by its usefulness. (c) Universidad Naciona...

  20. Genesis of petroduric and petrocalcic horizons in Latinamerica volcanic soils

    Science.gov (United States)

    Quantin, Paul

    2010-05-01

    Introduction. In Latinamerica, from Mexico to Chile, there are indurated volcanic soils horizons, named 'tepetate' in Mexico or cangahua in the Andes Mountains. Apart from original volcanic tuffs, these horizons were produced by pedogenesis: either through a former weathering of volcanic ash layers into fragic and later to petrocalcic horizons; or after a former soil formation through a second process of transformation from clayey volcanic soils to silicified petroduric horizons. This oral presentation will briefly deal with the formation of petroduric horizons in Mexico and petrocalcic horizon in Ecuador. Petroduric horizon genesis in Mexico. A soil climato-toposequence, near to Veracruz (Rossignol & Quantin, 1997), shows downwards an evolution from a ferralic Nitisol to a petroduric Durisol. A Durisol profile comports these successive horizons: at the top A and Eg, then columnar Btg-sim, laminar Bt-sim , prismatic Bsim, plinthite Cg, over andesite lava flow. Among its main features are especially recorded: clay mineralogy, microscopy and HRTEM. These data show: an increase in cristobalite at the expenses of 0.7 nm halloysite in Egsiltans, laminar Bt-sim, around or inside the columns or prisms of Btg-sim and Bsimhorizons. HRTEM (Elsass & al 2000) on ultra thin sections reveals an 'epigenesis' of clay sheets by amorphous silica, to form successively A-opal, Ct-opal and microcrystalline cristobalite. From these data and some groundwater chemical analyses, a scenario of duripan formation from a past clayey Nitisol is inferred: clay eluviation-illuviation process? alternate redoximorphy? clay degradation, Al leaching and Si accumulation, to form successively A-opal, Ct-opal and cristobalite. Petrocalcic horizon genesis in Ecuador. A soil climato-toposequence on pyroclastic flows, near to Bolivar in Ecuador (Quantin & Zebrowski, 1997), shows downwards the evolution from fragic-eutric-vitric Cambisols to petrocalcic-vitric Phaeozems, at the piedmont under semi

  1. Functional MRI: Genesis, State of the art and the Sequel

    International Nuclear Information System (INIS)

    Bharath, Rose Dawn

    2014-01-01

    The last 25 years have seen functional magnetic resonance imaging (fMRI) grow from an interesting experimental imaging technique in the hands of some to a primary investigation of choice in the localization and lateralization of brain function prior to surgery. Developments in the field of computational neurosciences have transformed fMRI analysis from classical subtractive type analysis to dynamic casual modeling, and now to graph theory analysis. This has widened the scope of fMRI, and is therefore finding applications in understanding neural correlates of diseases like autism and Alzheimer's disease, prognostication of diseases like traumatic brain injury, and has the potential to direct therapy. It is unfortunately true that this widened ambit has not received the clinical attention it deserves, probably because fMRI is susceptible to artifacts from skull base and blood products and has reduced sensitivity in patients with vascular malformations, or because a change in medical practice usually lags behind the technological and scientific developments that make it possible. This review focuses on the developmental chronology of fMRI image analysis in the last 25 years with highlights on major milestones like developments in the field of paradigms, analysis methods, resting state fMRI, and functional connectivity. To make the statistical images of brain at work more colorful, the article starts with genesis of fMRI and ends with the hope of a promising bright future. Many inputs for this article are obtained from a series of 103 review articles edited by Bandettini et al., compiling personal experiences of pioneers in this field. Interested readers are encouraged to refer to these for a more complete overview.

  2. Comparative study of angio genesis radiopharmaceuticals for melanoma detection

    International Nuclear Information System (INIS)

    Oliveira, Erica Aparecida de

    2011-01-01

    Early diagnosis and treatment of melanoma, a cutaneous tumor with a serious prognosis, is extremely important for optimal clinical outcome. Phage display peptide libraries are a useful screening resource for identifying bioactive peptides that interact with cancer targets. The aim of this study was the evaluation of two technetium-99m tracers for angio genesis detection in melanoma model, using cyclic peguilated pentapeptide with RGD and NGR motifs conjugated with bifunctional chelator MAG3. The conjugated peptides (10 μL of a μg/μL solution) were labeled with technetium-99m using a sodium tartrate buffer. Radiochemical evaluation was done by ITLC and confirmed by HPLC. Partition coefficient was determined and internalization assays were performed in two melanoma cells (B16F10 and SKMEL28). Biodistribution evaluation of the tracers was done in healthy animals at different times and also in mice bearing the tumor cells at 120 min post injection. Blocking studies were also conducted by co-injection of cold peptides. The conjugated showed the same profile in many evaluations. They were radiolabeled with high radiochemical purity (>97%). Both were hydrophilic, with preferential renal excretion. Tumor uptake was higher for human melanoma cells than for murinic melanoma cells, specially for 99m Tc-MAG3-PEG 8 -c(RGDyK) (7.85±±2.34 %ID/g) at 120 min post injection. The performance of 99m Tc-MAG 3 -PEG 8 -c(RGDyk) was much better than NGR tracer concerning human melanoma uptake and might be considered in future investigations focusing radiotracers for melanoma diagnosis. (author)

  3. The genesis solar-wind sample return mission

    International Nuclear Information System (INIS)

    Wiens, Roger C.

    2009-01-01

    different solar isotopic composition and each invoking a different early solar-system process to produce the heterogeneity. Other volatiles such as C, N, and H may also have experienced similar effects, but with only two isotopes it is often impossible to distinguish with these elements between mass-dependent fractionation and other effects such as mixing or mass-independent fractionation. Table 1 provides a summary of the major measurement objectives of the Genesis mission. Determining the solar oxygen isotopic composition is at the top of the list. Volatile element and isotope ratios constitute six of the top seven priorities. A number of disciplines stand to gain from information from the Genesis mission, as will be discussed later. Based on the Apollo solar-wind foil experiment, the Genesis mission was designed to capture solar wind over orders of magnitude longer duration and in a potentially much cleaner environment than the lunar surface.

  4. Tropical cyclone genesis in the Southern Hemisphere and its relationship with the ENSO

    Energy Technology Data Exchange (ETDEWEB)

    Kuleshov, Y.; Qi, L. [Australian Bureau of Meteorology, Melbourne, VIC (Australia). National Climate Centre; Chane Ming, F.; Chouaibou, I.; Hoareau, C. [UMR CNRS-Meteo-France-Univ. de la Reunion, La Reunion (France). Lab. de l' Atmosphere et des Cyclones; Roux, F. [Paul Sabatier Univ., CNRS, Toulouse (France). Lab. d' Aerologie

    2009-07-01

    Tropical cyclogenesis climatology over the South Indian and South Pacific Oceans has been developed using a new tropical cyclone (TC) archive for the Southern Hemisphere, and changes in geographical distribution of areas favourable for TC genesis related to changes in the El Nino-Southern Oscillation (ENSO) phases have been investigated. To explain these changes, large-scale environmental variables which influence TC genesis and development such as sea surface temperatures (SSTs), relative humidity in mid-troposphere, vertical wind shear and lower tropospheric vorticity have been examined. In the South Indian Ocean, reduction of TC genesis in the western part of the basin and its increase in the eastern part as well as displacement of the area favourable for TC genesis further away from the equator during La Nina events compared to El Nino events can be explained by changes in geographical distribution of relative humidity and vorticity across the basin as primary contributors; positive anomalies of SSTs observed during La Nina seasons in the eastern part of the basin additionally contribute to enhanced cyclogenesis near the Western Australia. In the South Pacific Ocean, changes in geographical distribution of relative humidity and vorticity appear to be the key large-scale environmental factors responsible for enhanced TC genesis in the eastern (western) part of the basin as well as for the northeast (southwest) shift of points of cyclogenesis during El Nino (La Nina) events, with vertical wind shear and SSTs as additional contributing large-scale environmental variables. (orig.)

  5. Decrease of tropical cyclone genesis frequency in the western North Pacific since 1960s

    Science.gov (United States)

    Hu, Feng; Li, Tim; Liu, Jia; Bi, Mingyu; Peng, Melinda

    2018-03-01

    Tropical cyclone (TC) genesis frequency in the western North Pacific (WNP) during 1960-2014 shows a step-by-step decrease on interdecadal timescale, in accordance to the phase of the Interdecadal Pacific Oscillation (IPO). The environmental parameters responsible for the interdecadal change of TC genesis frequency were investigated. It was found that vertical wind shear especially the zonal wind shear plays a critical role, while other parameters such as sea surface temperature (SST), vertical velocity, divergence, humidity and maximum potential intensity cannot explain the step-by-step decrease of TC genesis frequency. A further diagnosis shows that the interdecadal change of vertical wind shear is caused by SST and associated rainfall pattern changes across the Indo-Pacific Ocean. A stronger warming in the Indian Ocean/western Pacific from 1960-1976 to 1977-1998 led to enhanced convection over the Maritime Continent and thus strengthened vertical shear over the key TC genesis region in the WNP. A La Nina-like SST pattern change from 1977-1998 to 1999-2014 led to a strengthened Walker circulation in the tropical Pacific, which further enhanced the vertical shear and decreased TC genesis frequency in the WNP.

  6. Magma genesis at Gale Crater: Evidence for Pervasive Mantle Metasomatism

    Science.gov (United States)

    Filiberto, J.

    2017-12-01

    Basaltic rocks have been analyzed at Gale Crater with a larger range in bulk chemistry than at any other landing site [1]. Therefore, the rocks may have experienced significantly different formation conditions than those experienced by magmas at Gusev Crater or Meridiani Planum. Specifically, the rocks at Gale Crater have higher potassium than other Martian rocks, with a potential analog of the Nakhlite parental magma, and are consistent with forming from a metasomatized mantle source [2-4]. Mantle metasomatism would not only affect the bulk chemistry but mantle melting conditions, as metasomatism fluxes fluids into the source region. Here I will combine differences in bulk chemistry between Martian basalts to calculate formation conditions in the interior and investigate if the rocks at Gale Crater experienced magma genesis conditions consistent with metasomatism - lower temperatures and pressures of formation. To calculate average formation conditions, I rely on experimental results, where available, and silica-activity and Mg-exchange thermometry calculations for all other compositions following [5, 6]. The results show that there is a direct correlation between the calculated mantle potential temperature and the K/Ti ratio of Gale Crater rocks. This is consistent with fluid fluxed metasomatism introducing fluids to the system, which depressed the melting temperature and fluxed K but not Ti to the system. Therefore, all basalts at Gale Crater are consistent with forming from a metasomatized mantle source, which affected not only the chemistry of the basalts but also the formation conditions. References: [1] Cousin A. et al. (2017) Icarus. 288: 265-283. [2] Treiman A.H. et al. (2016) Journal of Geophysical Research: Planets. 121: 75-106. [3] Treiman A.H. and Medard E. (2016) Geological Society of America Abstracts with Programs. 48: doi: 10.1130/abs/2016AM-285851. [4] Schmidt M.E. et al. (2016) Geological Society of America Abstracts with Programs. 48: doi: 10

  7. Genesis Contingency Planning and Mishap Recovery: The Sample Curation View

    Science.gov (United States)

    Stansbery, E. K.; Allton, J. H.; Allen, C. C.; McNamara, K. M.; Calaway, M.; Rodriques, M. C.

    2007-01-01

    Planning for sample preservation and curation was part of mission design from the beginning. One of the scientific objectives for Genesis included collecting samples of three regimes of the solar wind in addition to collecting bulk solar wind during the mission. Collectors were fabricated in different thicknesses for each regime of the solar wind and attached to separate frames exposed to the solar wind during specific periods of solar activity associated with each regime. The original plan to determine the solar regime sampled for specific collectors was to identify to which frame the collector was attached. However, the collectors were dislodged during the hard landing making identification by frame attachment impossible. Because regimes were also identified by thickness of the collector, the regime sampled is identified by measuring fragment thickness. A variety of collector materials and thin films applied to substrates were selected and qualified for flight. This diversity provided elemental measurement in more than one material, mitigating effects of diffusion rates and/or radiation damage. It also mitigated against different material and substrate strengths resulting in differing effects of the hard landing. For example, silicon crystal substrates broke into smaller fragments than sapphire-based substrates and diamond surfaces were more resilient to flying debris damage than gold. The primary responsibility of the curation team for recovery was process documentation. Contingency planning for the recovery phase expanded this responsibility to include not only equipment to document, but also gather, contain and identify samples from the landing area and the recovered spacecraft. The team developed contingency plans for various scenarios as part of mission planning that included topographic maps to aid in site recovery and identification of different modes of transport and purge capability depending on damage. A clean tent, set-up at Utah Test & Training Range

  8. Kollig op Genesis 1-3: 'n verslag van verskuiwende denke en geloof

    OpenAIRE

    Spangenberg, Sakkie

    2014-01-01

    The author narrates how his views concerning Gen 1-3 have changed over the past forty years. He enrolled for theological training at the University of Stellenbosch during the seventies of the previous century and had to study the book Hoe lezen wij Genesis 2 en 3? ("How should we read Genesis 2 and 3?"). The book had been written by B. J. Oosterhoff, a Dutch scholar who argued a case for a symbolic reading of the text. Since then the author has become acquainted with the paradigm change in th...

  9. Delimitation Markers, Chapter Division, Syntax and Literary Structure: the Case of Genesis 37:1–2

    NARCIS (Netherlands)

    van Peursen, W.T.; Korpel, Marjo; Sanders, Paul

    2017-01-01

    Many modern Bible translations insert a heading between the end of Genesis 36 and the beginning of Genesis 37 such as ‘Joseph and his brothers’ or ‘Joseph’s dreams’. This suggests (1) that a new section starts at 37:1 and (2) that this section contains the Joseph story. That 37:1 marks a new start

  10. OUTCOMES REVIEW OF TOTAL KNEE REPLACEMENT WITH GENESIS II TOTAL KNEE SYSTEM: AUSTRALIAN ORTHOPAEDIC ASSOCIATION NATIONAL JOINT REPLACEMENT REGISTRY DATA

    Directory of Open Access Journals (Sweden)

    N. L. Logvinov

    2014-01-01

    Full Text Available ABSTRACT. The goal of the article was to review Genesis II Total Knee System use according to AoA NJRR report. Genesis II has been widely used in Russian Federation since 1996. The AoA NJRR report was studied in order to learn connection between number of revision procedures and surgeon’s skills or type of the System, adequate choice among cemented, cementless and hybrid fixation, number of surgeries using Genesis II Total Knee System annually, average revision rate for Genesis II and early cumulative revision rate.CONCLUSION. The systematic study of AoA NJRR allows us to make a conclusion that cemented fixation of Genesis II Total Knee System is mostly effective, and this fact is confirmed by domestic experience. 

  11. Weathering and genesis of Soils from Ellsworth Mountains, East Antarctica

    Science.gov (United States)

    Karoline Delpupo Souza, Katia; Schaefer, Carlos Ernesto; Michel, Roberto; Monari, Julia; Machado, Vania

    2015-04-01

    Knowledge on Antarctic soils from the Ellsworth Mountains (EM) are patchy comparatively with Dry Valleys soils from the Transantartic Mountains, and could help understand the genesis of cryogenic soils under extreme dry, cold desert conditions. The EM are a slightly arcuate 350-km-long north-northwest-trending mountain chain is bordered on the west by the polar plateau of West Antarctica and on the east by Ronne Ice Shelf. The range is as much as 90 km wide and constitutes one of the largest areas of exposed bedrock in West Antarctica. The stratigraphic succession in the EM includes strata from Cambriam to Permian in age. The objective of this study is to analyze the properties of soils from EM in order to identify the main factors and processes involved in soil formation under cold desert conditions in Antarctica. The sampling design aimed to represent the different geological substrates (marble-clast conglomerate, graywacke, argillite, conglomerate, black shale, marble and quartzite) as well as altitudinal levels and landforms within the same substrate. We characterized soils from EM regarding their morphological, physics and chemical properties. Soil samples were air dried and passed through 2 mm sieves. After removal of water soluble salts, the samples were submitted to chemical and physical analyses such as: pH in water, potential acidity (H + Al), exchangeable bases, total organic carbon, electric conductivity, soil texture and color. The soils classify, for the most part, in weathering stages 1 to 2. Only in the upper parts of ridges were there traces of soils at weathering stage 3. This indicates that much of the present icefree topography has been overridden by ice within the last few hundred thousand years. Cryoturbation is a widespread phenomenon in this area resulting in intense cryoclastic weathering and patterned ground, forming sorted circles, stripes and gelifluxion lobes. The soil show low horizontation, discrete patches of salt on the surface, and

  12. 76 FR 21403 - Notice of Availability of the Final Environmental Impact Statement for the Genesis Project...

    Science.gov (United States)

    2011-04-15

    ...: (1) The cumulative impacts of mining and related actions on affected resources, for example water... DEPARTMENT OF THE INTERIOR Bureau of Land Management [LLNV010000.L19900000.EX0000 241A; 11-08807... the Genesis Project, Eureka County, NV AGENCY: Bureau of Land Management, Interior. ACTION: Notice of...

  13. Landscape formation and soil genesis in volcanic parent materials in humid tropical lowlands of Costa Rica

    NARCIS (Netherlands)

    Nieuwenhuyse, A.

    1996-01-01


    The influence of volcanism on landscape genesis, and formation of soils on volcanic parent material was studied in the Atlantic lowland of Costs Rica. This lowland is a subduction basin of tectonic origin, in which thick alluvial and marine sediments are accumulated. At its southwestern

  14. The Instrumental Genesis Process in Future Primary Teachers Using Dynamic Geometry Software

    Science.gov (United States)

    Ruiz-López, Natalia

    2018-01-01

    This paper, which describes a study undertaken with pairs of future primary teachers using GeoGebra software to solve geometry problems, includes a brief literature review, the theoretical framework and methodology used. An analysis of the instrumental genesis process for a pair participating in the case study is also provided. This analysis…

  15. Basement to surface expressions and critical factors in the genesis of unconformity-related deposits

    International Nuclear Information System (INIS)

    Potter, Eric

    2014-01-01

    Two subprojects: 1) Basement to surface expressions of deep mineralization and refinement of critical factors leading to the genesis of unconformity-related uranium deposits; and 2) Recognition of uranium ore system alteration signatures in complex terranes: IOCG vs albite-hosted uranium vs volcanic-hosted uranium.

  16. Genesis 2–3 and Alcibiades's speech in Plato's Symposium : A ...

    African Journals Online (AJOL)

    Genesis 2–3 and Alcibiades's speech in Plato's Symposium : A cultural critical reading. ... Abstract. The purpose of this article is to discuss some basic problems and methodological steps concerning the encounter between Hebrews and Greeks in the Classical period and its impact on the Hellenistic era. The relationship ...

  17. About estimation of the contamination of territorial-administrative regions of the Chernobyl genesis radionuclides

    International Nuclear Information System (INIS)

    Berezhnoj, A.V.

    2005-01-01

    It is recommended to realize the matching territorial-administrative regions on degree of the contamination their of the Chernobyl genesis radionuclides to size generalised index gravity of the radionuclide soiling region. The methodology of the calculation indexes is offered. The results executed estimation are briefly stated. (authors)

  18. Taking an Instrumental Genesis Lens: New Insights into Collaborative Mobile Learning

    Science.gov (United States)

    Cerratto Pargman, Teresa; Nouri, Jalal; Milrad, Marcelo

    2018-01-01

    In this paper, we argue that in order to gain a deeper understanding of collaborative mobile learning in schools, it is important to know not only how mobile devices affect collaborative learning but also how collaborative learning emerges and is mediated by these devices. We develop our argument by applying the instrumental genesis theory and the…

  19. Genesis of iron-apatite ores in Posht-e-Badam Block (Central Iran ...

    Indian Academy of Sciences (India)

    Central Iran; iron-apatite ore; Kiruna-type; Posht-e-Badam Block; REE geochemistry. J. Earth Syst ... ferent ore genesis models have been proposed for ...... volatile-rich magma systems stress the important .... Laco magnetite flow deposits, northern Chile: An up-to- ... economic report on iron ore prevision of the Esfahan steel.

  20. Re-interpreting Genesis 34 in the Light of Religious Violence in ...

    African Journals Online (AJOL)

    Religion plays significant roles in social harmony, yet it also serves as a motivation for violence. In Nigeria, religion has been at the centre of most violent conflicts, thereby gaining notoriety as one of the prime security challenges confronting the country. Genesis 34 is an important chapter in the Old Testament Bible.

  1. NONINVASIVE NASAL MUCOSA EXPOSURE TO TREAT AND PREVENT RHINITIS AND RHINOSINUSITIS OF VARIOUS GENESIS

    Directory of Open Access Journals (Sweden)

    E. Yu. Radtsig

    2014-07-01

    Full Text Available The paper deals with the evaluation of the nasal mucosa in health and in different abnormalities. It describes the possibilities of using drugs of different groups to relieve symptoms in nasal mucosal and paranasal sinus abnormalities of different genesis, as well as the preventive effect of some of these drugs.

  2. Cellulose Acetate Replica Cleaning Study of Genesis Non-Flight Sample 3CZ00327

    Science.gov (United States)

    Kuhlman, K. R.; Schmeling, M.; Gonzalez, C. P.; Allton, J. H.; Burnett, D. S.

    2014-01-01

    The Genesis mission collected solar wind and brought it back to Earth in order to provide precise knowledge of solar isotopic and elemental compositions. The ions in the solar wind were stopped in the collectors at depths on the order of 10 to a few hundred nanometers. This shallow implantation layer is critical for scientific analysis of the composition of the solar wind and must be preserved throughout sample handling, cleaning, processing, distribution, preparation and analysis. We are working interactively with the community of scientists analyzing Genesis samples, using our unique laboratory facilities -- and, where needed, our unique cleaning techniques -- to significantly enhance the science return from the Genesis mission. This work is motivated by the need to understand the submicron contamination on the collectors in the Genesis payload as recovered from the crash site in the Utah desert, and -- perhaps more importantly -- how to remove it. That is, we are evaluating the effectiveness of the wet-chemical "cleaning" steps used by various investigators, to enable them to design improved methods of stripping terrestrial contamination from surfaces while still leaving the solar-wind signal intact.

  3. PSYCHOANALYTIC INTERPRETATION OF JUSTICE IN CONTEXT OF PROBLEMS OF TECHNO-GENESIS (Part II

    Directory of Open Access Journals (Sweden)

    N. I. Mushinskij

    2009-01-01

    Full Text Available Carl Gustav Jung, Erich Fromm, Karen Horney, Jacques Lacan, Gilles Deleuze, Felix Guattari continue to develop a psychoanalytic theory of Freud under modern conditions. They investigate archetypes of unconscious which are linked with up-to-date conception of Justice. Ethics of psychoanalysis interprets the category of Justice from humanistic positions in the context of the techno-genesis processes.

  4. Tropical cyclone genesis in the Southern Hemisphere and its relationship with the ENSO

    Directory of Open Access Journals (Sweden)

    Y. Kuleshov

    2009-06-01

    Full Text Available Tropical cyclogenesis climatology over the South Indian and South Pacific Oceans has been developed using a new tropical cyclone (TC archive for the Southern Hemisphere, and changes in geographical distribution of areas favourable for TC genesis related to changes in the El Niño-Southern Oscillation (ENSO phases have been investigated. To explain these changes, large-scale environmental variables which influence TC genesis and development such as sea surface temperatures (SSTs, relative humidity in mid-troposphere, vertical wind shear and lower tropospheric vorticity have been examined. In the South Indian Ocean, reduction of TC genesis in the western part of the basin and its increase in the eastern part as well as displacement of the area favourable for TC genesis further away from the equator during La Niña events compared to El Niño events can be explained by changes in geographical distribution of relative humidity and vorticity across the basin as primary contributors; positive anomalies of SSTs observed during La Niña seasons in the eastern part of the basin additionally contribute to enhanced cyclogenesis near the Western Australia. In the South Pacific Ocean, changes in geographical distribution of relative humidity and vorticity appear to be the key large-scale environmental factors responsible for enhanced TC genesis in the eastern (western part of the basin as well as for the northeast (southwest shift of points of cyclogenesis during El Niño (La Niña events, with vertical wind shear and SSTs as additional contributing large-scale environmental variables.

  5. Is the poleward migration of tropical cyclone maximum intensity associated with a poleward migration of tropical cyclone genesis?

    Science.gov (United States)

    Daloz, Anne Sophie; Camargo, Suzana J.

    2018-01-01

    A recent study showed that the global average latitude where tropical cyclones achieve their lifetime-maximum intensity has been migrating poleward at a rate of about one-half degree of latitude per decade over the last 30 years in each hemisphere. However, it does not answer a critical question: is the poleward migration of tropical cyclone lifetime-maximum intensity associated with a poleward migration of tropical cyclone genesis? In this study we will examine this question. First we analyze changes in the environmental variables associated with tropical cyclone genesis, namely entropy deficit, potential intensity, vertical wind shear, vorticity, skin temperature and specific humidity at 500 hPa in reanalysis datasets between 1980 and 2013. Then, a selection of these variables is combined into two tropical cyclone genesis indices that empirically relate tropical cyclone genesis to large-scale variables. We find a shift toward greater (smaller) average potential number of genesis at higher (lower) latitudes over most regions of the Pacific Ocean, which is consistent with a migration of tropical cyclone genesis towards higher latitudes. We then examine the global best track archive and find coherent and significant poleward shifts in mean genesis position over the Pacific Ocean basins.

  6. Petrography, alteration and genesis of iron mineralization in Roshtkhar

    Directory of Open Access Journals (Sweden)

    Habib Biabangard

    2017-07-01

    Full Text Available Introduction Iron mineralization in Roshtkhar is located in 48 Km east of the city of Roshtkhar and south of the Khorasan Razavi province. It is geologically located in the north east of the Lut block and the Khaf-Bardeskan volcano-plutonic belt. The Khaf-Bardeskan belt is an important metallogenic province since it is a host of valuable ore deposits such as the Kuh-e-Zar Au-Spicularite, the Tanourcheh and the Khaf Iron ore deposits (Karimpour and Malekzadeh Shafaroudi, 2007. Iron and Copper mineralization in this belt are known as the hydrothermal, skarn and IOCG types (Karimpour and Malekzadeh Shafaroudi, 2007. IOCG deposits are a new type of magmatic to hydrothermal mineralization in the continental crust (Hitzman et al., 1992. Precambrian marble, Lower Paleozoic schist and metavolcanics are the oldest rocks of the area. The younger units are Oligocene conglomerate, shale and sandstone, Miocene marl and Quaternary deposits. Iron oxides and Cu sulfides are associated with igneous rocks. Fe and Cu mineralization in Roshtkhar has been subject of a few studies such as Yousefi Surani (2006. This study describes the petrography of the host rocks, ore paragenesis, alteration types, geochemistry, genesis and other features of the Fe and Cu mineralization in the Roshtkhar iron. Methods After detailed field studies and sampling, 30 thin sections and 20 polished sections that were prepared from host rocks and ores were studied by conventional petrographic and mineraloghraphic methods in the geology department of the University of Sistan and Baluchestan. 5 samples from the alteration zones were examined by XRD in the Yamagata University in Japan, and 8 samples from the less altered ones were analyzed by XRF and ICP-OES in the Kharazmi University and the Iranian mineral processing research center (IMPRC in Karaj, respectively. The XRF and ICP-OES data are presented in Table 1. Result and discussion The host rocks of the Roshtkhar Iron deposit are diorite

  7. Cleaning Genesis Mission Payload for Flight with Ultra-Pure Water and Assembly in ISO Class 4 Environment

    Science.gov (United States)

    Allton, Judith H.

    2012-01-01

    Genesis mission to capture and return to Earth solar wind samples had very stringent contamination control requirements in order to distinguish the solar atoms from terrestrial ones. Genesis mission goals were to measure solar composition for most of the periodic table, so great care was taken to avoid particulate contamination. Since the number 1 and 2 science goals were to determine the oxygen and nitrogen isotopic composition, organic contamination was minimized by tightly controlling offgassing. The total amount of solar material captured in two years is about 400 micrograms spread across one sq m. The contamination limit requirement for each of C, N, and O was <1015 atoms/sq cm. For carbon, this is equivalent to 10 ng/cm2. Extreme vigilance was used in pre-paring Genesis collectors and cleaning hardware for flight. Surface contamination on polished silicon wafers, measured in Genesis laboratory is approximately 10 ng/sq cm.

  8. The instrumental genesis process in future primary teachers using Dynamic Geometry Software

    Science.gov (United States)

    Ruiz-López, Natalia

    2018-05-01

    This paper, which describes a study undertaken with pairs of future primary teachers using GeoGebra software to solve geometry problems, includes a brief literature review, the theoretical framework and methodology used. An analysis of the instrumental genesis process for a pair participating in the case study is also provided. This analysis addresses the techniques and types of dragging used, the obstacles to learning encountered, a description of the interaction between the pair and their interaction with the teacher, and the type of language used. Based on this analysis, possibilities and limitations of the instrumental genesis process are identified for the development of geometric competencies such as conjecture creation, property checking and problem researching. It is also suggested that the methodology used in the analysis of the problem solving process may be useful for those teachers and researchers who want to integrate Dynamic Geometry Software (DGS) in their classrooms.

  9. Three Proposed Compendia for Genesis Solar Wind Samples: Science Results, Collector Materials Characterization and Cleaning Techniques

    Science.gov (United States)

    Allton, J. H.; Calaway, M. J.; Nyquist, L. E.; Jurewicz, A. J. G.; Burnett, D. S.

    2018-01-01

    Final Paper and not the abstract is attached. Introduction: Planetary material and cosmochemistry research using Genesis solar wind samples (including the development and implementation of cleaning and analytical techniques) has matured sufficiently that compilations on several topics, if made publically accessible, would be beneficial for researchers and reviewers. We propose here three compendia based on content, organization and source of documents (e.g. published peer-reviewed, published, internal memos, archives). For planning purposes, suggestions are solicited from potential users of Genesis solar wind samples for the type of science content and/or organizational style that would be most useful to them. These compendia are proposed as living documents, periodically updated. Similar to the existing compendia described below, the curation compendia are like library or archival finding aids, they are guides to published or archival documents and should not be cited as primary sources.

  10. GENESI-DR: Discovery, Access and on-Demand Processing in Federated Repositories

    Science.gov (United States)

    Cossu, Roberto; Pacini, Fabrizio; Parrini, Andrea; Santi, Eliana Li; Fusco, Luigi

    2010-05-01

    GENESI-DR (Ground European Network for Earth Science Interoperations - Digital Repositories) is a European Commission (EC)-funded project, kicked-off early 2008 lead by ESA; partners include Space Agencies (DLR, ASI, CNES), both space and no-space data providers such as ENEA (I), Infoterra (UK), K-SAT (N), NILU (N), JRC (EU) and industry as Elsag Datamat (I), CS (F) and TERRADUE (I). GENESI-DR intends to meet the challenge of facilitating "time to science" from different Earth Science disciplines in discovery, access and use (combining, integrating, processing, …) of historical and recent Earth-related data from space, airborne and in-situ sensors, which are archived in large distributed repositories. In fact, a common dedicated infrastructure such as the GENESI-DR one permits the Earth Science communities to derive objective information and to share knowledge in all environmental sensitive domains over a continuum of time and a variety of geographical scales so addressing urgent challenges such as Global Change. GENESI-DR federates data, information and knowledge for the management of our fragile planet in line with one of the major goals of the many international environmental programmes such as GMES, GEO/GEOSS. As of today, 12 different Digital Repositories hosting more than 60 heterogeneous dataset series are federated in GENESI-DR. Series include satellite data, in situ data, images acquired by airborne sensors, digital elevation models and model outputs. ESA has started providing access to: Category-1 data systematically available on Internet; level 3 data (e.g., GlobCover map, MERIS Global Vegetation Index); ASAR products available in ESA Virtual Archive and related to the Supersites initiatives. In all cases, existing data policies and security constraints are fully respected. GENESI-DR also gives access to Grid and Cloud computing resources allowing authorized users to run a number of different processing services on the available data. The GENESI

  11. Visual Representation in GENESIS as a tool for Physical Modeling, Sound Synthesis and Musical Composition

    OpenAIRE

    Villeneuve, Jérôme; Cadoz, Claude; Castagné, Nicolas

    2015-01-01

    The motivation of this paper is to highlight the importance of visual representations for artists when modeling and simulating mass-interaction physical networks in the context of sound synthesis and musical composition. GENESIS is a musician-oriented software environment for sound synthesis and musical composition. However, despite this orientation, a substantial amount of effort has been put into building a rich variety of tools based on static or dynamic visual representations of models an...

  12. Geochemical geochronology and genesis of granite from Coronel Murta, Northeast of Minas Gerais, Brazil

    International Nuclear Information System (INIS)

    Soares, A.C.P.; Siga Junior, O.

    1987-01-01

    Geological, petrographic, geochemical (including rare-earth elements) and geochronological data of the Coronel Murta (Northeast Minas Gerais State) post-tectonic intrusive alkalic granites were summarized in order to discuss their genesis. This paper shows that Coronel Murta granites were generated by anatexis of dominantly metasedimentary rocks, in an ensialic environment, as the late results of an intraplate A-type subduction during the Brazilian Cycle. (author) [pt

  13. Potential Vorticity Streamers as Precursors to Tropical Cyclone Genesis in the Western Pacific

    Science.gov (United States)

    2012-03-01

    study a developing system with an extratropical precursor (TCS-037) developing into Tropical Storm 16W (TS 16W)” (Schönenberger 2010). This subsection...tropopause maps), the TC genesis event is termed a tropical transition (TT) case. If no such extratropical feature 38 is present, the storm in... extratropical origin is deemed to play an important role in the dynamical evolution leading to tropical cyclogenesis. In contrast, non-TT storms

  14. Dynamics and Predictability of Tropical Cyclone Genesis, Structure and Intensity Change

    Science.gov (United States)

    2012-09-30

    analyses and forecasts of tropical cyclones, including genesis, intensity change, and extratropical transition. A secondary objective is to understand... storm -centered assimilation algorithm. Basic research in Report Documentation Page Form ApprovedOMB No. 0704-0188 Public reporting burden for the...COMPLETED For the four storms consider (Nuri, Jangmi, Sinlaku, and Hagupit), an 80-member EnKF has been cycled on observations (surface, rawinsondes, GPS

  15. On the genesis of pyrite-polymetallic deposits of the Rudnyi Altai

    International Nuclear Information System (INIS)

    Puchkov, E.V.; Najdenov, B.M.

    1986-01-01

    Results of lead isotope composition measurements in pyrite-polymetallic deposits of the Rudnyi Altai are presented. Porphyr dating by zirconium has shown isochronous age of 552 million years. Lead of galenites of various generations and galenite form of lead of pyrit provide similar lead-isotope values with model age of 370 million years. The isotopic-geochemical data obtained are interpreted as applied to the deposit genesis

  16. NR2A contributes to genesis and propagation of cortical spreading depression in rats.

    Science.gov (United States)

    Bu, Fan; Du, Ruoxing; Li, Yi; Quinn, John P; Wang, Minyan

    2016-03-22

    Cortical spreading depression (CSD) is a transient propagating excitation of synaptic activity followed by depression, which is implicated in migraine. Increasing evidence points to an essential role of NR2A-containing NMDA receptors in CSD propagation in vitro; however, whether these receptors mediate CSD genesis in vivo requires clarification and the role of NR2A on CSD propagation is still under debate. Using in vivo CSD in rats with electrophysiology and in vitro CSD in chick retina with intrinsic optical imaging, we addressed the role of NR2A in CSD. We demonstrated that NVP-AAM077, a potent antagonist for NR2A-containing receptors, perfused through microdialysis probes, markedly reduced cortex susceptibility to CSD, but also reduced magnitude of CSD genesis in rats. Additionally, NVP-AAM077 at 0.3 nmol perfused into the contralateral ventricle, considerably suppressed the magnitude of CSD propagation wave and propagation rate in rats. This reduction in CSD propagation was also observed with TCN-201, a negative allosteric modulator selective for NR2A, at 3 μM, in the chick retina. Our data provides strong evidence that NR2A subunit contributes to CSD genesis and propagation, suggesting drugs selectively antagonizing NR2A-containing receptors might constitute a highly specific strategy treating CSD associated migraine with a likely better safety profile.

  17. Molecular Contamination on Anodized Aluminum Components of the Genesis Science Canister

    Science.gov (United States)

    Burnett, D. S.; McNamara, K. M.; Jurewicz, A.; Woolum, D.

    2005-01-01

    Inspection of the interior of the Genesis science canister after recovery in Utah, and subsequently at JSC, revealed a darkening on the aluminum canister shield and other canister components. There has been no such observation of film contamination on the collector surfaces, and preliminary spectroscopic ellipsometry measurements support the theory that the films observed on the anodized aluminum components do not appear on the collectors to any significant extent. The Genesis Science Team has made an effort to characterize the thickness and composition of the brown stain and to determine if it is associated with molecular outgassing.Detailed examination of the surfaces within the Genesis science canister reveals that the brown contamination is observed to varying degrees, but only on surfaces exposed in space to the Sun and solar wind hydrogen. In addition, the materials affected are primarily composed of anodized aluminum. A sharp line separating the sun and shaded portion of the thermal closeout panel is shown. This piece was removed from a location near the gold foil collector within the canister. Future plans include a reassembly of the canister components to look for large-scale patterns of contamination within the canister to aid in revealing the root cause.

  18. Modelling the genesis of equatorial podzols: age and implications for carbon fluxes

    Science.gov (United States)

    Doupoux, Cédric; Merdy, Patricia; Régina Montes, Célia; Nunan, Naoise; José Melfi, Adolpho; José Ribeiro Pereira, Osvaldo; Lucas, Yves

    2017-05-01

    Amazonian podzols store huge amounts of carbon and play a key role in transferring organic matter to the Amazon River. In order to better understand their C dynamics, we modelled the formation of representative Amazonian podzol profiles by constraining both total carbon and radiocarbon. We determined the relationships between total carbon and radiocarbon in organic C pools numerically by setting constant C and 14C inputs over time. The model was an effective tool for determining the order of magnitude of the carbon fluxes and the time of genesis of the main carbon-containing horizons, i.e. the topsoil and deep Bh. We performed retrocalculations to take into account the bomb carbon in the young topsoil horizons (calculated apparent 14C age from 62 to 109 years). We modelled four profiles representative of Amazonian podzols, two profiles with an old Bh (calculated apparent 14C age 6.8 × 103 and 8.4 × 103 years) and two profiles with a very old Bh (calculated apparent 14C age 23.2 × 103 and 25.1 × 103 years). The calculated fluxes from the topsoil to the perched water table indicate that the most waterlogged zones of the podzolized areas are the main source of dissolved organic matter found in the river network. It was necessary to consider two Bh carbon pools to accurately represent the carbon fluxes leaving the Bh as observed in previous studies. We found that the genesis time of the studied soils was necessarily longer than 15 × 103 and 130 × 103 years for the two younger and two older Bhs, respectively, and that the genesis time calculated considering the more likely settings runs to around 15 × 103-25 × 103 and 150 × 103-250 × 103 years, respectively.

  19. A climatological model of North Indian Ocean tropical cyclone genesis, tracks and landfall

    Science.gov (United States)

    Wahiduzzaman, Mohammad; Oliver, Eric C. J.; Wotherspoon, Simon J.; Holbrook, Neil J.

    2017-10-01

    Extensive damage and loss of life can be caused by tropical cyclones (TCs) that make landfall. Modelling of TC landfall probability is beneficial to insurance/re-insurance companies, decision makers, government policy and planning, and residents in coastal areas. In this study, we develop a climatological model of tropical cyclone genesis, tracks and landfall for North Indian Ocean (NIO) rim countries based on kernel density estimation, a generalised additive model (GAM) including an Euler integration step, and landfall detection using a country mask approach. Using a 35-year record (1979-2013) of tropical cyclone track observations from the Joint Typhoon Warning Centre (part of the International Best Track Archive Climate Stewardship Version 6), the GAM is fitted to the observed cyclone track velocities as a smooth function of location in each season. The distribution of cyclone genesis points is approximated by kernel density estimation. The model simulated TCs are randomly selected from the fitted kernel (TC genesis), and the cyclone paths (TC tracks), represented by the GAM together with the application of stochastic innovations at each step, are simulated to generate a suite of NIO rim landfall statistics. Three hindcast validation methods are applied to evaluate the integrity of the model. First, leave-one-out cross validation is applied whereby the country of landfall is determined by the majority vote (considering the location by only highest percentage of landfall) from the simulated tracks. Second, the probability distribution of simulated landfall is evaluated against the observed landfall. Third, the distances between the point of observed landfall and simulated landfall are compared and quantified. Overall, the model shows very good cross-validated hindcast skill of modelled landfalling cyclones against observations in each of the NIO tropical cyclone seasons and for most NIO rim countries, with only a relatively small difference in the percentage of

  20. The Old English Genesis and Milton’s Paradise Lost: the characterisation of Satan

    Directory of Open Access Journals (Sweden)

    Elisa Ramazzina

    2016-07-01

    Full Text Available The aim of this study is to determine whether and to what extent the English poet John Milton may have been influenced in the composition of Paradise Lost by the Old English poem known as Genesis B. The paper will examine similarities and dif-ferences in the characterisation of Satan and of the temptation of Adam and Eve in both poems. The comparison between two of the illuminations of the Junius 11 ms. and the corresponding passages in Paradise Lost will be part of the analysis.

  1. The Old English Genesis and Milton's Paradise Lost: the characterisation of Satan

    OpenAIRE

    Ramazzina, Elisa

    2016-01-01

    The aim of this study is to determine whether and to what extent the English poet John Milton may have been influenced in the composition of Paradise Lost by the Old English poem known as Genesis B. The paper will examine similarities and dif-ferences in the characterisation of Satan and of the temptation of Adam and Eve in both poems. The comparison between two of the illuminations of the Junius 11 ms. and the corresponding passages in Paradise Lost will be part of the analysis.

  2. Development of Chemical and Mechanical Cleaning Procedures for Genesis Solar Wind Samples

    Science.gov (United States)

    Schmeling, M.; Jurewicz, A. J. G.; Gonzalez, C.; Allums, K. K.; Allton, J. H.

    2018-01-01

    The Genesis mission was the only mission returning pristine solar material to Earth since the Apollo program. Unfortunately, the return of the spacecraft on September 8, 2004 resulted in a crash landing shattering the solar wind collectors into smaller fragments and exposing them to desert soil and other debris. Thorough surface cleaning is required for almost all fragments to allow for subsequent analysis of solar wind material embedded within. However, each collector fragment calls for an individual cleaning approach, as contamination not only varies by collector material but also by sample itself.

  3. Research on petrologic, geochemical characteristics and genesis of volcanic rocks in Dachangsha basin

    International Nuclear Information System (INIS)

    Wei Sanyuan

    1999-01-01

    On the basis of research on petrologic, geochemical characteristics and isotope composition of volcanic rocks in Dachangsha basin, the author concludes that the volcanic rocks formed from magma of different genesis and depth are double-cycle effusive. It is proposed that the magma forming the intermediate-basic volcanics of the first cycle comes from the mixing of the partial melting of the deep crust and mantle, and the intermediate-acidic volcanics of the secondary cycle are derived from the remelting of the upper crust

  4. On the genesis of spatio-temporal self-organized structures in plasma devices

    International Nuclear Information System (INIS)

    Talasman, S.J.; Sanduloviciu, M.

    1995-01-01

    The genesis of luminous sharply defined nearly spherical space charges structures formed in an Argon plasma column was experimental investigated. The results reveal spatio-temporal characteristics proper to systems resulting after a self-organization process. Their phenomenology involves electrical charges separation produced by symmetry breaking and spatial separation of the excitation and ionization cross sections functions in a region where electrons are accelerated and, as a result, the appearance of electrostatic forces that, acting as long range correlations, assures, together with dissipative effects, its stability. (Author) 8 Figs., 31 Refs

  5. Recent Optical and SEM Characterization of Genesis Solar Wind Concentrator Diamond on Silicon Collector

    Science.gov (United States)

    Allton, Judith H.; Rodriquez, M. C.; Burkett, P. J.; Ross, D. K.; Gonzalez, C. P.; McNamara, K. M.

    2013-01-01

    One of the 4 Genesis solar wind concentrator collectors was a silicon substrate coated with diamond-like carbon (DLC) in which to capture solar wind. This material was designed for analysis of solar nitrogen and noble gases [1, 2]. This particular collector fractured during landing, but about 80% of the surface was recovered, including a large piece which was subdivided in 2012 [3, 4, 5]. The optical and SEM imaging and analysis described below supports the subdivision and allocation of the diamond-on-silicon (DOS) concentrator collector.

  6. Seismo-tectonic model regarding the genesis and occurrence of Vrancea (Romania) earthquakes

    International Nuclear Information System (INIS)

    Enescu, D.; Enescu, B.D.

    1998-01-01

    The first part of this paper contains a very short description of some previous attempts in seismo-tectonic modeling of Vrancea zone. The seismo-tectonic model developed by the authors of this work is presented in the second part of the paper. This model is based on the spatial distribution of hypo-centers and focal mechanism characteristics. Lithosphere structure and tectonics of the directly implied zones represent very important characteristics of the seismo-tectonic model. Some two-dimensional and three-dimensional sketches of the model, which satisfy all the above mentioned characteristics and give realistic explanations regarding the genesis and occurrence of Vrancea earthquakes are presented. (authors)

  7. Tumour genesis syndrome: severe hypophosphatemia and hypokalemia may be ominous presenting findings in childhood acute myeloid leukaemia.

    Science.gov (United States)

    Chan, Winnie Ky; Chang, Kai On; Lau, Wing Hung

    2017-08-01

    We report a 16-year-old girl who was diagnosed with acute leukaemia and a marked leucocytosis >200 × 10 9 /L. She presented with marked hypophosphatemia, hypokalemia, acute renal failure and acute respiratory failure. These electrolytes disturbances may indicate rapid tumour genesis. These ominous findings required urgent treatment to halt the crises of rapid leukemic cell proliferation. Mark hypophosphatemia and hypokalemia may be presenting electrolyte abnormalities in a patient with acute leukaemia, and these may be indicators of aggressive tumour genesis. What is known: • Mild electrolyte disturbances are common in oncology patients • Tumour lysis syndrome is well recognized by paediatriaticians What is new: • Life-threatening hypophosphatemia is an uncommon presentation • These electrolytes disorders may indicate an aggressive tumour genesis process even at presentation and require urgent treatment.

  8. ENSO Effect on East Asian Tropical Cyclone Landfall via Changes in Tracks and Genesis in a Statistical Model

    Science.gov (United States)

    Yonekura, Emmi; Hall, Timothy M.

    2014-01-01

    Improvements on a statistical tropical cyclone (TC) track model in the western North Pacific Ocean are described. The goal of the model is to study the effect of El Nino-Southern Oscillation (ENSO) on East Asian TC landfall. The model is based on the International Best-Track Archive for Climate Stewardship (IBTrACS) database of TC observations for 1945-2007 and employs local regression of TC formation rates and track increments on the Nino-3.4 index and seasonally varying climate parameters. The main improvements are the inclusion of ENSO dependence in the track propagation and accounting for seasonality in both genesis and tracks. A comparison of simulations of the 1945-2007 period with observations concludes that the model updates improve the skill of this model in simulating TCs. Changes in TC genesis and tracks are analyzed separately and cumulatively in simulations of stationary extreme ENSO states. ENSO effects on regional (100-km scale) landfall are attributed to changes in genesis and tracks. The effect of ENSO on genesis is predominantly a shift in genesis location from the southeast in El Nino years to the northwest in La Nina years, resulting in higher landfall rates for the East Asian coast during La Nina. The effect of ENSO on track propagation varies seasonally and spatially. In the peak activity season (July-October), there are significant changes in mean tracks with ENSO. Landfall-rate changes from genesis- and track-ENSO effects in the Philippines cancel out, while coastal segments of Vietnam, China, the Korean Peninsula, and Japan show enhanced La Nina-year increases.

  9. The impact of Saharan Dust on the genesis and evolution of Hurricane Earl (2010)

    Science.gov (United States)

    Pan, B.; Wang, Y.; Hsieh, J. S.; Lin, Y.; Hu, J.; Zhang, R.

    2017-12-01

    Dust, one of the most abundant natural aerosols, can exert substantial radiative and microphysical effects on the regional climate and has potential impacts on the genesis and intensification of tropical cyclones (TCs). A Weather Research and Forecasting Model and the Regional Oceanic Modeling System coupled model (WRF-ROMS) is used to simulate the evolution of Hurricane Earl (2010), of which Earl was interfered by Saharan dust at the TC genesis stage. A new dust module has been implemented to the TAMU two-moment microphysics scheme in the WRF model. It accounts for both dust as Cloud Condensation Nuclei (CCN) and Ice Nuclei (IN). The hurricane track, intensity and precipitation have been compared to the best track data and TRMM precipitation, respectively. The influences of Saharan dust on Hurricane Earl are investigated with dust-CCN, dust-IN, and dust-free scenarios. The analysis shows that Saharan dust changes the latent heat and moisture distribution, invigorates the convections in the hurricane's eyewall, and suppresses the development of Earl. This finding addresses the importance of accounting dust microphysics effect on hurricane predictions.

  10. [Spatial organization of bioelectrical brain activity in epilepsy and amenorrhea of central genesis].

    Science.gov (United States)

    Avakian, G N; Oleĭnikova, O M; Nerobkova, L N; Dovletkhanova, E R; Mitrofanov, A A; Gusev, E I

    2002-01-01

    The study aimed at modification of co-herent analysis (CA), as a mathematical method for EEG data processing for objective evaluation of bioelectric brain activity spatial organization in women with epilepsy and secondary amenorrhea of central genesis. One hundred sixty one women (30 with epilepsy, 116 with amenorrhea and 115 controls aged 15 to 41 years) have been examined. Characteristic changes of cortico-cortical inter- and intra-hemisphere relations for patients with catamenial (CTM) and noncatamenial (NCTM) epilepsy in different menstrual cycle terms were found. The most distinct changes were detected in theta-activity analysis. In the beginning of menstrual cycle, the patients with CTM epilepsy exhibited higher CA indices in theta-rhythm range in all right hemisphere pairs studied. On the contrary, patients with NCTM epilepsy exhibited lower CA indices mainly in the right brain hemisphere. alpha-rhythm spatial organization analysis in the same patients showed similar correlations, but they were better expressed in alpha-rhythm generation zone: in the beginning of menstrual cycle CA indices were high in patients with CTM epilepsy and low in those with NCTM epilepsy. Comparing to controls, patients with secondary amenorrhea of central genesis showed most distinct changes in theta-activity towards the CA indices increase in the majority of the leads. In patients with epilepsy and amenorrhea, CA indices of right brain hemisphere and intra-central temporal lead pairs were lower than in patients with amenorrhea without epilepsy by both alpha- and theta-rhythms.

  11. Some aspects of the genesis of heavy mineral assemblages in Lower Proterozoic uranium-gold conglomerates

    International Nuclear Information System (INIS)

    Clemmey, H.

    1982-01-01

    Some genetic models for Lower Proterozoic gold- and uranium-bearing pyritic conglomerates favour a modified placer origin in which low levels of atmospheric oxygen are used to account for the survival of uraninite and pyrite. There are many difficulties with such models. New evidence concerning the genesis of the deposits is derived from a clast of ferric iron clay thought to represent a precursor sediment of the Witwatersrand Basin. Reworking of such clays and transport of a magnetite and ferric clay assemblage with subsequent sulphidation, could account for the porous pyrites, the absence of magnetite and the lack of hydraulic equivalence of the mineral grains in the conglomerates. The presence of oxygen, as indicated by the ferric iron clasts, would account for the evidence of mobility of uranium and of gold and would enhance their extraction from source rocks; particularly the release of gold from a precursor auriferous iron formation source. It is suggested that some aspects of the genesis of uranium deposits of the Witwatersrand and Elliott Lake may be similar to those of the Phanerozoic 'Roll Front' ores involving interaction between oxidizing uraniferous groundwaters and previously sulphidized and reduzate facies sediments. (author)

  12. Audio-magnetotelluric (AMT) study to investigate the genesis of Mujil hill

    Science.gov (United States)

    Rahmania, Suryanto, Wiwit

    2017-07-01

    Gunung Mujil is an isolated hill located near Pondoworejo village, Kalibawang sub-district, Kulon Progo district, and Special Province of Yogyakarta. The hill is part of the eastern Kulon Progo mountain range extended relatively in the North-South direction. The lithology of the hill consists of andesite breccia and it's similar with the Old Andesite Formation that built the Kulon Progo Mountains. There are at least two hypothesis about the genesis and the formation mechanism of this hill, (1) it was formed by debris mass from Kulon Progo Mountains, and (2) ) it was formed by an intrusion. Our study intended to determine the subsurface resistivity below the hill and to relating those results to with the scenario of the genesis of the Mujil hill. We conducted Audio-magnetotellurics (AMT) measurements along two lines survey crossing the Mujil hill consisting of 20 measurements. Since the measurements are located near the villages, most of the data has a fair to bad quality and only one station yielded an excellent data. A 1D Forward modeling was then applied to find best-fit model of the AMT data. The results shows that the Mujil hill was built by debris mass of the Old Andesite Formation from Kulon Progo mountain which is represented by a lower resistivity value under the Mujil hill.

  13. A mouse model for monitoring islet cell genesis and developing therapies for diabetes

    Directory of Open Access Journals (Sweden)

    Yoshinori Shimajiri

    2011-03-01

    Transient expression of the transcription factor neurogenin-3 marks progenitor cells in the pancreas as they differentiate into islet cells. We developed a transgenic mouse line in which the surrogate markers secreted alkaline phosphatase (SeAP and enhanced green florescent protein (EGFP can be used to monitor neurogenin-3 expression, and thus islet cell genesis. In transgenic embryos, cells expressing EGFP lined the pancreatic ducts. SeAP was readily detectable in embryos, in the media of cultured embryonic pancreases and in the serum of adult animals. Treatment with the γ-secretase inhibitor DAPT, which blocks Notch signaling, enhanced SeAP secretion rates and increased the number of EGFP-expressing cells as assayed by fluorescence-activated cell sorting (FACS and immunohistochemistry in cultured pancreases from embryos at embryonic day 11.5, but not in pancreases harvested 1 day later. By contrast, treatment with growth differentiation factor 11 (GDF11 reduced SeAP secretion rates. In adult mice, partial pancreatectomy decreased, whereas duct ligation increased, circulating SeAP levels. This model will be useful for studying signals involved in islet cell genesis in vivo and developing therapies that induce this process.

  14. The Genesis of Romanian Football. Social Factors and Processes behind the Game

    Directory of Open Access Journals (Sweden)

    PÉTER, László

    2014-12-01

    Full Text Available The present article deals with those social and economic factors that contributed to the genesis of Romanian soccer at the turn of the previous century. The author argues that football was imported from abroad via peregrination and schools, but certain social processes, such as urbanization, capitalization and the appearance of massive working classes, are the reasons why this beautiful game became socially embedded in the local environments. The different circumstances in Banat and Transylvania and in the old Romanian Kingdom marked the social history and trajectory “travelled” by the ball. While in the western part of the country, football arrived in a fertile ground because of the already existing bourgeois sport associations and the rapidly emerging local working classes, the role of foreign companies and expats in implementing football was more significant in the southern regions. This difference in the genesis of the game produced two distinct styles of playing football. These two styles clearly reflect the historical and social background specific to the different regions.

  15. Interdecadal Change of Tropical Cyclone Genesis Controlling Parameter in Western North Pacific

    Science.gov (United States)

    Li, T.

    2017-12-01

    The main environmental parameter controlling tropical cyclone (TC) genesis in the western North Pacific (WNP) changed in different interdecadal periods. The interannual variability of TC genesis frequency was primarily control by specific humidity in 1950-1976, sea surface temperature (SST) in 1977-1998, and vorticity in 1999-2014. A further diagnosis shows that the change of environmental specific humidity during 1950-1976 was attributed to anomalous advection of mean moisture during ENSO developing summer. The SST change during 1977-1998 was associated with circulation change during ENSO decaying summer. The change of environment vorticity was primarily related to CP-type El Niño during 1999-2014. The ultimate cause of the controlling parameter change is attributed to the change of ENSO behavior. Compared to the first period, a stronger EP-type ENSO variability in the second period leads to a stronger circulation/SST response during ENSO decaying phase. The occurrence of more frequent CP type El Niño in the third period was responsible for greater vorticity controlling in the WNP.

  16. Enhanced Cleaning of Genesis Solar Wind Sample 61348 for Film Residue Removal

    Science.gov (United States)

    Allums, K. K.; Gonzalez, C. P.; Kuhlman, K. R.; Allton, J. H.

    2015-01-01

    The Genesis mission returned to Earth on September 8, 2004, experiencing a nonnominal reentry. During the recovery of the collector materials from the capsule, many of the collector fragments were placed on the adhesive protion of post-it notes to prevent the fragments from moving during transport back to Johnson Space Center. This unknowingly provided an additional contaminate that would prove difficult to remove with the limited chemistries allowed in the Genesis Curation Laboratory. Generally when collector material samples are prepared for allocation to PIs, the samples are cleaned front side only with Ultra-Pure Water (UPW) via megasonic dispersion to the collector surface to remove crash debris and contamination. While this cleaning method works well on samples that were not placed on post-its during recovery, it has caused movement of the residue on the back of the sample to be deposited on the front in at least two examples. Therefore, samples placed on the adhesive portion on post-it note, require enhanced cleaning methods since post-it residue has proved resistant to UPW cleaning.

  17. MINING LAKES OF THE AGHIREŞ AREA: GENESIS, EVOLUTION AND MORPHOMETRIC ASPECTS

    Directory of Open Access Journals (Sweden)

    V. MĂCICĂŞAN

    2012-03-01

    Full Text Available Mining lakes of the Aghireş area: Genesis, evolution and morphometric aspects. Mining activities are heavily influencing and destroying the landscape worldwide. In Aghireş mining perimeter, exploitation workings have led to extreme and irreversible environmental damages, especially regarding the geomorphologic and hydrological situation. After cessation of underground mining and initiation of quarry exploitation, certain mining galleries collapsed and were afterwards flooded by precipitation and re-ascending groundwater, leading to the formation of lacustrine units. Later, the abandoned quarries have undergone the same flooding process. In this paper, we report on the genesis, evolution and the current characteristics of these bodies of water, referred to as mining lakes. In addition, using the GIS technology, the morphometry of the mining lakes is presented in this paper. Due to their predominant current use, as for recreational purposes, the sustainable management of the mining lakes is an important ecological and socio-economical factor for the Aghireş area. For the majority of mining lakes, restoration measures may be necessary due to the demands of the European legislation as well as to the demands of a specific socio-economic use in the future (e.g. bathing lakes or fishing lakes. These aspects of investigation will constitute a prerequisite for effective environmental management and rehabilitation strategies.

  18. Vrou as beeld van God, Deel 1: 'n Historiese ondersoek - Vanaf Genesis tot die Middeleeue

    Directory of Open Access Journals (Sweden)

    Yolanda Dreyer

    2000-12-01

    Full Text Available Woman created in the image of God, Part 1: a historical investigation - from Genesis to the Middle Ages. This study indicates that the traditions in the Pentateuch, especially the creation traditions, implied the egalitarian status of man and woman as image of God. The context of this traditions, however, was patriarchal and thus opened the possibility of the exploitation of women. Though Genesis 1:27 does not specifically attest to the asymmetry between man and woman in patriarchal society, the fate of women in general was bound up with the presentation of God as a male creator. The implications of this presentation can be clearly seen in texts of the intertestamental period. The study points out the degree to which Philo's view of a hierarchy concerning man and woman as immanent to God's order of creation, strongly influenced Christian thought on the place of women. Since the "fall of woman" necessitates a "soteriology", women in general are portrayed negatively in patristic texts. Mary is seen as the positive counterpart of Eve. The image of women then becomes that of submission on account of their alienation from God. The article concludes with the view of Thomas Aquinas that the subservience of slaves is less than that of women, because in their case it is not an order of creation.

  19. Implication of neuro-genesis during brain development in behavior disorders caused by depleted uranium

    International Nuclear Information System (INIS)

    Legrand, Marie

    2016-01-01

    Humans are continuously exposed to neurotoxic compounds in the environment. The developing brain is more susceptible to neurotoxic compounds and modifications in its growth could lead to disorders in adulthood. Uranium (U) is an environmental heavy metal and induces behavioral disorders as well as affects neurochemistry. The aim of my thesis was to investigate whether depleted uranium (DU) exposure affects neuro-genesis processes, which are implicated in brain development and in synaptic plasticity in adults. While DU increased cell proliferation in the hippocampal neuro-epithelium and decreased cell death at prenatal stages, DU lead to opposite effects in the dentate gyrus at postnatal stages. Moreover, DU had an inhibitory effect on the transition toward neuronal differentiation pathway during development. At adult stage, DU induced a decrease in neuronal differentiation but has no impact in cell proliferation. Finally, DU exposure during brain development caused depressive like behavior at late postnatal and adult stage, and decreased spatial memory at adult stage. Consequently, DU exposure during brain development caused modification in neuro-genesis processes associated to cognitive and emotional disorders at adult age. U could present a threat to human health, especially in pregnant women and children. (author)

  20. Die teologies-polemiese gerigtheid van Genesis 1-3: implikasies vir die gereformeerde leer oor die erfsonde

    Directory of Open Access Journals (Sweden)

    N. Vorster

    2009-07-01

    Full Text Available The theological polemic purpose of Genesis 1-3: implications for the reformed doctrine on original sin This article focuses on the polemic nature of Genesis 1-3 and the implications thereof on the reformed doctrine regarding original sin. In the first place the views of the creation narratives as historical-literal and mythological material are discussed. Thereafter the article proposes that the creation narratives must be treated as theological material with a polemic and prophetic purpose. The implications of this for the reformed doctrine on original sin are subsequently discussed.

  1. Paulus als Schriftuitlegger Paulus’ vertolking van Genesis 15:5b-6 in Romeinen 4:3

    Directory of Open Access Journals (Sweden)

    Pieter K. Baaij

    2005-07-01

      In this article the author illustrates that Paul in Romans 4:3 accurately renders what is written in Genesis 15:5b and 6. Paul teaches us to understand the Hebrew text better by indicating where the emphasis lies in the Hebrew text and how we must interpret the Hebrew terms used. For this reason Paul’s interpretation of Genesis 15:5b and 6 in Romans 4:3 is of great importance in the continually more topical debate on how we must translate the Bible.

  2. Magma genesis and slab-wedge interaction across an island arc-continent collision zone, East Sunda Arc, Indonesia

    NARCIS (Netherlands)

    Hoogewerff, J.A.

    1999-01-01

    This thesis presents the results of a detailed trace element and isotope geochemistry study into the magma-genesis ofvolcanoes in the Adonara-Pantar Section (APS) ofthe East Sunda Arc in Indonesia, a setting where an oceanic island arc is colliding with a passive continental margin. Sr, Nd, Pb, Ra,

  3. Magma genesis and slab-wedge interaction across an island arc-continent collision zone, East Sunda Arc, Indonesia

    NARCIS (Netherlands)

    Hoogewerff, J.A.

    1999-01-01

    This thesis presents the results of a detailed trace element and isotope geochemistry study into the magma-genesis ofvolcanoes in the Adonara-Pantar Section (APS) ofthe East Sunda Arc in Indonesia, a setting where an oceanic island arc is colliding with a passive continental margin. Sr, Nd, Pb,

  4. 75 FR 52966 - Notice of Availability of the Final Environmental Impact Statement for the Genesis Solar, LLC...

    Science.gov (United States)

    2010-08-30

    ... following Web site: http://www.blm.gov/ca/st/en/fo/palmsprings/Solar_Projects/Genesis_Ford_Dry_Lake.html.... Construction and operation of the Proposed Action would disturb a total of about 1,800 acres within the site... facilities for storm water flow and discharge. 6. Temporary construction laydown area(s) within the larger...

  5. Genealogies and spiritualities in Genesis 4:17-22, 4:25-26, 5:1-32 ...

    African Journals Online (AJOL)

    The three genealogies in Genesis 4:17-22, 4:25-26 en 5:1-32 show different intentions: the first wants (amongst other purposes) to give an aetiology of the trades; the second wants to stress the importance of a new beginning; the third wants to relate Adam to Noah. Each of these approaches to genealogy has a different ...

  6. Improvement of orthopedic dental treatment of patients suffering post-surgery defects of the maxilla of cancer genesis

    Directory of Open Access Journals (Sweden)

    A. S. Arutyunov

    2015-01-01

    Full Text Available The paper presents a comprehensive study identifying the key issuesand giving the mathematical, and clinical and microbiological substantiation of modern principles of providing orthopedic dental care to patients with acquired defects of the upper jaw of cancer genesis.

  7. Between normal and pathological: Ludwik Fleck, Georges Canguilhem and the genesis of historical epistemology

    Directory of Open Access Journals (Sweden)

    Mauro Lucio Leitão Condé

    2016-05-01

    Full Text Available The main purpose of this article is to address, starting from some aspects of the thought of Ludwik Fleck and Georges Canguilhem, the genesis of historical epistemology in the history of science. Specifically, it seeks the contribution of the biological matrix, or the life sciences, presented by these authors, as a central framework in the constitution of historical epistemology. In other words, more than a search of similarities between Fleck and Canguilhem, the main goal is to show how, in formulating independently their ideas of history of science – especially the history of medicine – these authors contributed decisively to the basis of a historical epistemology that will be, throughout the twentieth century, a new thought style for understanding the history of science.

  8. The genesis of the Brazilian nation in XIX century’s iconography

    Directory of Open Access Journals (Sweden)

    Verediana C. da Silva

    2013-06-01

    Full Text Available This research aims to understand the genesis of the idea of Brazilian nation through the nineteenth century’s iconography, approaching the study of images and deepening into the analysis of four artworks: Engenho da cachoeira. Corte de cana-de-açúcar by Hércule Florence, Primeira Missa no Brasil by Victor Meirelles, O Grito do Ipiranga by Pedro Américo and Evangelho das Selvas by Benedito Calixto. Besides the pictures we paid attention to the texts belonging to the same period, mainly those produced by the cultural elite related to the Instituto Histórico e Geográfico Brasileiro (IHGB, to the travel reports as text-images, as well as to the emergence of the Instituto and of the Academia Imperial de Belas Artes (AIBA in a context of pursuit of homogeneity in the promising Brazilian nation.

  9. The genesis of period-adding bursting without bursting-chaos in the Chay model

    International Nuclear Information System (INIS)

    Yang Zhuoqin; Lu Qishao; Li Li

    2006-01-01

    According to the period-adding firing patterns without chaos observed in neuronal experiments, the genesis of the period-adding 'fold/homoclinic' bursting sequence without bursting-chaos is explored by numerical simulation, fast/slow dynamics and bifurcation analysis of limit cycle in the neuronal Chay model. It is found that each periodic bursting, from period-1 to period-7, is separately generated by the corresponding periodic spiking pattern through two period-doubling bifurcations, except for the period-1 bursting occurring via a Hopf bifurcation. Consequently, it can be revealed that this period-adding bursting bifurcation without chaos has a compound bifurcation structure with transitions from spiking to bursting, which is closely related to period-doubling bifurcations of periodic spiking in essence

  10. Beyond the hypothesis: Theory's role in the genesis, opposition, and pursuit of the Higgs boson

    Science.gov (United States)

    Wells, James D.

    2018-05-01

    The centrally recognized theoretical achievement that enabled the Higgs boson discovery in 2012 was the hypothesis of its existence, made by Peter Higgs in 1964. Nevertheless, there is a significant body of comparably important theoretical work prior to and after the Higgs boson hypothesis. In this article we present an additional perspective of how crucial theory work was to the genesis of the Higgs boson hypothesis, especially emphasizing its roots in Landau's theory of phase transitions and subsequent theoretical work on superconductivity. A detailed description is then given of the opposition to the Higgs boson hypothesis by many researchers, giving evidence to its speculative nature. And finally, it is discussed the importance of theory work in the decades after the hypothesis in order to make possible the experimental discovery of the Higgs boson.

  11. The understanding of co-owners' rights in the context of the genesis of environmental rights

    Directory of Open Access Journals (Sweden)

    Kudeikina I.

    2014-01-01

    Full Text Available Environmental rights obtain a special importance in the context of real distribution of joint property. The common practice, where the building regulations are applied to legal relationships when carrying out the real distribution of a joint property, is associated with the genesis of environmental rights, but cannot be supported by the doctrine of absolutism of the property rights. In this Article, the author analyzes the legal reasoning and legal consequences of applicability of environmental rights. The essence of real distribution of joint property is the termination of the joint property as a legal act without a target of environmental transformation. The real distribution of joint property is not an action leaving any environmental impacts. The author concludes that the application of the environmental rights to the real distribution of the joint property unreasonably limits the property rights of co-owners.

  12. Geological characteristics and genesis of Niangnianggong gold-silver deposit in Liaoning Province, China

    International Nuclear Information System (INIS)

    Hou Zhenyuan

    2013-01-01

    Based on the analysis of geological characteristics and genesis of Niangnianggong deposit, this paper suggested that the deposit is controlled by the EW direction faults and belongs to quartz vein type. Average value of δ 34 S of the ore is 2.19‰, and the variation ranges from 1.6‰ to 4.9‰, which shows the feature of hydrothermal sulfur. The result of lead isotope is fall into original lead zone, which shows the feature of primeval lead system. The result of H-O isotope is close to meteoric line, which means the participation of precipitations. Rb-Sr age of ore is 186.6 Ma, which is similar to the age of diorite dike. Multi-disciplinary analysis concludes that the deposit is a quartz vein type deposit with composite hydrothermal origin. (author)

  13. The genesis of victimization surveys and of the realist-constructionist divide.

    Science.gov (United States)

    de Castelbajac, Matthieu

    2017-09-01

    The invention of victimization surveys is often presented as a synthesis of the two theoretical attitudes that, supposedly, dominated the 1960s debate over official crime statistics: realism and social constructionism. This paper turns this genesis story on its head. Using original archives, I argue that victimization surveys responded to organizational opportunities in the field of applied research. It was only after the fact that two of their architects seized the debate on crime measurement to broadcast their invention. In so doing they strategically recast the terms of this debate into a binary division between two antithetical social ontologies. This case is used to discuss how social scientists come to reinterpret and misunderstand their history. © 2017 Wiley Periodicals, Inc.

  14. Genesis and evolution of the Skyrme model from 1954 to the present

    International Nuclear Information System (INIS)

    Sanyuk, V.I.

    1994-01-01

    Not widely known facts on the genesis of the Skyrme model are presented in a historical survey, based on Skyrme's earliest papers and on his own published remembrance. We consider the evolution of Skyrme's model description of nuclear matter from the ''Mesonic Fluid'' model up to its final version, known as the baryon model. We pay special tribute to some well-known ideas in contemporary particle physics which one can find in Skyrme's earlier papers, such as: Nuclear Democracy, the Solitonic Mechanism, the Nonlinear Realization of Chiral Symmetry, Topological Charges, Fermi-Bose Transmutation, etc. It is curious to note in the final version of the Skyrme model gleams of Kelvin's ''Vortex Atoms'' theory. In conclusion we make a brief analysis of the validity of Skyrme's conjectures in view of recent results and pinpoint some questions which still remain. (author). 93 refs, 4 figs

  15. Sun-genesis 21: Empowering the global village in the digital age and the solar century

    Energy Technology Data Exchange (ETDEWEB)

    Hamasaki, Les [Los Angeles, CA (United States)

    2000-07-01

    Sun-Genesis 21 is a global economic development plan for creating an environmentally sustainable future in the developing world. Its premise is that the solution to the survival of civil stability and democracy in developing countries in the Information Age is to slow the migration of the rural poor into the urban centers as well as dispersing some of the residents of the already impacted cities into new agro-communities. This strategy envisions empowering the 25 million coffee farmers located in the poorest countries in the world to control their own economic destiny by marketing their products directly to the international marketplace over the World Wide Web (Coffee Belt Plan 2020). The plan also envisions creating a network of new agricultural communities called World Farm Solar Telecommunities that utilizes telecommunications and environmental technologies to disperse the impacted urban population. Proven profitable commodities such as industrial hemp, aloe vera, and aquacultural farming will be the economic foundation of these agro-communities. The goal is to empower rural agro-entrepreneurs to become an economic engine for job creation and be able to afford the Coffee Solar Televillages that include distant learning centers, telemedicine clinics, food processing centers, e-commerce centers, and solar crop-drying centers. The Genesis 21 program includes creative financing strategies to deal with these massive problems of poverty and hunger through the concept of trade, not aid, including the use of barter in a proposed Green Technology for Green Coffee program. [Spanish] Sun-Genesis 21 es un plan global de desarrollo economico para crear un futuro ambiental sustentable en el mundo en desarrollo. La premisa del plan es que la solucion para la supervivencia de la estabilidad civil y la democracia en paises en desarrollo dentro de la Era de la Informacion es desacelerar la migracion de la gente pobre de las areas rurales hacia los centros urbanos, asi como

  16. GENESIS OF INTERPLANETARY INTERMITTENT TURBULENCE: A CASE STUDY OF ROPE–ROPE MAGNETIC RECONNECTION

    Energy Technology Data Exchange (ETDEWEB)

    Chian, Abraham C.-L.; Loew, Murray H. [Department of Biomedical Engineering, George Washington University, Washington, DC 20052 (United States); Feng, Heng Q. [Institute of Space Physics, Luoyang Normal University, Luoyang (China); Hu, Qiang [Department of Space Science and CSPAR, University of Alabama in Huntsville, Huntsville, AL 35805 (United States); Miranda, Rodrigo A. [UnB-Gama Campus, and Plasma Physics Laboratory, Institute of Physics, University of Brasília (UnB), Brasília DF 70910-900 (Brazil); Muñoz, Pablo R. [Department of Physics and Astronomy, University of La Serena, Av. Juan Cisternas 1200, La Serena (Chile); Sibeck, David G. [NASA Goddard Space Flight Center, Greenbelt, MD 20771 (United States); Wu, De J., E-mail: abraham.chian@gmail.com [Purple Mountain Observatory, Chinese Academy of Sciences, Nanjing 210008 (China)

    2016-12-01

    In a recent paper, the relation between current sheet, magnetic reconnection, and turbulence at the leading edge of an interplanetary coronal mass ejection was studied. We report here the observation of magnetic reconnection at the interface region of two interplanetary magnetic flux ropes. The front and rear boundary layers of three interplanetary magnetic flux ropes are identified, and the structures of magnetic flux ropes are reconstructed by the Grad–Shafranov method. A quantitative analysis of the reconnection condition and the degree of intermittency reveals that rope–rope magnetic reconnection is the most likely site for genesis of interplanetary intermittency turbulence in this event. The dynamic pressure pulse resulting from this reconnection triggers the onset of a geomagnetic storm.

  17. On gravity's role in the genesis of rest masses of classical fields

    Science.gov (United States)

    Szabados, László B.

    2018-03-01

    It is shown that in the Einstein-conformally coupled Higgs-Maxwell system with Friedman-Robertson-Walker symmetries the energy density of the Higgs field has stable local minimum only if the mean curvature of the t=const hypersurfaces is less than a finite critical value χ _c, while for greater mean curvature the energy density is not bounded from below. Therefore, there are extreme gravitational situations in which even quasi-locally defined instantaneous vacuum states of the Higgs sector cannot exist, and hence one cannot at all define the rest mass of all the classical fields. On hypersurfaces with mean curvature less than χ _c the energy density has the `wine bottle' (rather than the familiar `Mexican hat') shape, and the gauge field can get rest mass via the Brout-Englert-Higgs mechanism. The spacelike hypersurface with the critical mean curvature represents the moment of `genesis' of rest masses.

  18. Endothelial Progenitor Cell Dysfunction in Polycystic Ovary Syndrome: Implications for The Genesis of Cardiovascular Diseases

    Directory of Open Access Journals (Sweden)

    Yu-Hsun Kao

    2013-01-01

    Full Text Available Polycystic ovary syndrome (PCOS, the most common endocrine disorder affecting women ofreproductive age, is characterized by hyperandrogenism and insulin resistance. Women withPCOS have a higher risk for cardiovascular diseases (CVDs and endothelial dysfunction. Themechanisms underlying these risks are unclear. Human peripheral blood contains circulatingendothelial progenitor cells (EPCs derived from bone marrow that have the ability to proliferate anddifferentiate into mature endothelial cells, which may contribute to vessel homeostasis and repair.PCOS is associated with insulin resistance, hyperinsulinemia, and dyslipidemia, which may resultin EPC dysfunction. In this review, we summarize the potential mechanisms of EPC dysfunction inPCOS, which possibly result in a higher genesis of CVDs in PCOS-affected subjects.

  19. Scale genesis and gravitational wave in a classically scale invariant extension of the standard model

    Energy Technology Data Exchange (ETDEWEB)

    Kubo, Jisuke [Institute for Theoretical Physics, Kanazawa University,Kanazawa 920-1192 (Japan); Yamada, Masatoshi [Department of Physics, Kyoto University,Kyoto 606-8502 (Japan); Institut für Theoretische Physik, Universität Heidelberg,Philosophenweg 16, 69120 Heidelberg (Germany)

    2016-12-01

    We assume that the origin of the electroweak (EW) scale is a gauge-invariant scalar-bilinear condensation in a strongly interacting non-abelian gauge sector, which is connected to the standard model via a Higgs portal coupling. The dynamical scale genesis appears as a phase transition at finite temperature, and it can produce a gravitational wave (GW) background in the early Universe. We find that the critical temperature of the scale phase transition lies above that of the EW phase transition and below few O(100) GeV and it is strongly first-order. We calculate the spectrum of the GW background and find the scale phase transition is strong enough that the GW background can be observed by DECIGO.

  20. Electron microscope study of the genesis of strain-induced martensite embryos

    International Nuclear Information System (INIS)

    Staudhammer, K.P.; Hecker, S.S.; Murr, L.E.

    1984-01-01

    Previous work of Olson and Cohen and Murr, et al., is used to describe the genesis of martensite embryos which form at the intersection of microscopic shear bands in deformed type 304 stainless steel. It is shown that the intersection volume included within intersecting shear bands contains irregular and smaller dispersed volume segments forming α' martensite (bcc). These correspond to the satisfaction of specific intersections of stacking faults or partial dislocations on approximately every second (111)/sub fcc/ plane in one direction, and every third (111)/sub fcc/ plane in the other (conjugate) direction. The requisite stacking fault or partial dislocation arrangements are produced in an irregular fashion resulting in α' martensite embryos nucleating in an incomplete and irregular fashion within the intersection volume. 9 references, 2 figures

  1. Large-Scale Influences on the Genesis of Tropical Cyclone Karl (2010)

    Science.gov (United States)

    Griffin, K.; Bosart, L. F.

    2012-12-01

    The events leading up to the genesis of Tropical Cyclone (TC) Karl (2010) provides a unique opportunity to examine the continuing problem of understanding tropical cyclogenesis. The PRE-Depression Investigation of Cloud-systems in the Tropics (PREDICT) field campaign allowed for detailed investigation of the tropical disturbance that served as the precursor to TC Karl as it progressed westward through the Caribbean Sea. The purpose of this presentation is to examine the evolution of the pre-Karl disturbance using both common synoptic-scale analyses as well as statistically-based equatorial wave analyses, focusing on where these analyses complement and enhance each other. One of the major factors in the initial spin-up of the pre-Karl tropical disturbance is a surge of southerly and westerly winds from northern South America on 8-10 September 2010. As the surge entered the Caribbean on 9 September, it aided in the formation of a nearly closed earth-relative cyclonic circulation near the southern Leeward Islands. This circulation weakened late on 10 September and remained weak through 13 September before increased organization led to TC genesis on 14 September. This southerly wind surge can be traced to a well-defined surge of anomalously cold air and enhanced southerly winds originating in the lee of the Argentinian Andes over a week prior. While the temperature anomalies wash out prior to reaching the equator, anomalous low-level winds progress into Colombia and Venezuela, where topography aids in turning the southerly winds eastward. An investigation of the pre-Karl environment utilizing wavenumber-frequency filtering techniques also suggests that the initial spin-up of pre-Karl can be associated with the active phase of a convectively coupled Kelvin wave (CCKW). The observed formation of the nearly closed cyclonic circulation on 10 September is well timed with the passage of anomalous westerly winds along and behind the convectively active phase of a CCKW. These

  2. The genesis of period-adding bursting without bursting-chaos in the Chay model

    International Nuclear Information System (INIS)

    Yang Zhuoqin; Lu Qishao; Li Li

    2006-01-01

    According to the period-adding firing patterns without chaos observed in neuronal experiments, the genesis of the period-adding 'fold/homoclinic' bursting sequence without bursting-chaos is explored by numerical simulation, fast/slow dynamics and bifurcation analysis of limit cycle in the neuronal Chay model. It is found that each periodic bursting, from period-1 to 7, is separately generated by the corresponding periodic spiking pattern through two period-doubling bifurcations, except for the period-1 bursting occurring via a Hopf bifurcation. Consequently, it can be revealed that this period-adding bursting bifurcation without chaos has a compound bifurcation structure with transitions from spiking to bursting, which is closely related to period-doubling bifurcations of periodic spiking in essence

  3. Extraction of Solar Wind Nitrogen and Noble Gases From the Genesis Gold Foil Collector

    Science.gov (United States)

    Schlutter, D. J.; Pepin, R. O.

    2005-12-01

    The Genesis gold foil is a bulk solar wind collector, integrating fluences from all three of the wind regimes. Pyrolytic extraction of small foil samples at Minnesota yielded He fluences, corrected for backscatter, in good agreement with measurements by on-board spacecraft instruments, and He/Ne elemental ratios close to those implanted in collector foils deployed on the lunar surface during the Apollo missions. Isotopic distributions of He, Ne and Ar are under study. Pyrolysis to temperatures above the gold melting point generates nitrogen blanks large enough to obscure the solar-wind nitrogen component. An alternative technique for nitrogen and noble gas extraction, by room-temperature amalgamation of the gold foil surface, will be discussed. Ne and Ar releases in preliminary tests of this technique on small foil samples were close to 100% of the amounts expected from the high-temperature pyrolysis yields, indicating that amalgamation quantitatively liberates gases from several hundred angstroms deep in the gold, beyond the implantation depth of most of the solar wind. Present work is focused on two problems currently interfering with accurate nitrogen measurements at the required picogram to sub-picogram levels: a higher than expected blank likely due to tiny air bubbles rolled into the gold sheet during fabrication, and the presence of a refractory hydrocarbon film on Genesis collector surfaces (the "brown stain") that, if left in place on the foil, shields the underlying gold from mercury attack. We have found, however, that the film is efficiently removed within tens of seconds by oxygen plasma ashing. Potential nitrogen contaminants introduced during the crash of the sample return canister are inert in amalgamation, and so are not hazards to the measurements.

  4. Genesis Solar Wind Collector Cleaning Assessment: Update on 60336 Sample Case Study

    Science.gov (United States)

    Goreva, Y. S.; Allums, K. K.; Gonzalez, C. P.; Jurewicz, A. J.; Burnett, D. S.; Allton, J. H.; Kuhlman, K. R.; Woolum, D.

    2015-01-01

    To maximize the scientific return of Genesis Solar Wind return mission it is necessary to characterize and remove a crash-derived particle and thin film surface contamination. A small subset of Genesis mission collector fragments are being subjected to extensive study via various techniques. Here we present an update on the sample 60336, a Czochralski silicon (Si-CZ) based wafer from the bulk array (B/C). This sample has undergone multiple cleaning steps (see the table below): UPW spin wash, aggressive chemical cleanings (including aqua regia, hot xylene and RCA1), as well as optical and chemical (EDS, ToF-SIMS) imaging. Contamination appeared on the surface of 60336 after the initial 2007 UPW cleaning. Aqua regia and hot xylene treatment (8/13/2013) did little to remove contaminants. The sample was UPW cleaned for the third time and imaged (9/16/13). The UPW removed the dark stains that were visible on the sample. However, some features, like "the Flounder" (a large, 100 micron feature in Fig. 1b) appeared largely intact, resisting all previous cleaning efforts. These features were likely from mobilized adhesive, derived from the Post-It notes used to stabilize samples for transport from Utah after the hard landing. To remove this contamination, an RCA step 1 organic cleaning (RCA1) was employed. Although we are still uncertain on the nature of the Flounder and why it is resistant to UPW and aqua regia/hot xylene treatment, we have found RCA1 to be suitable for its removal. It is likely that the glue from sticky pads used during collector recovery may have been a source for resistant organic contamination [9]; however [8] shows that UPW reaction with crash-derived organic contamination does not make particle removal more difficult.

  5. Genesis of the concept "mergers and acquisitions" in the world scientific knowledge

    Directory of Open Access Journals (Sweden)

    T. V. Reshetnikova

    2017-09-01

    Full Text Available The authors examine the genesis of the concepts of "merger" and "acquisition" in terms of their essence, the need for implementation in the modern economy, the role in the restructuring of the company or business as a whole, the forms of manifestation in the market of corporate control. The authors compare the classical approaches to the examination of essential characteristics in the foreign economic literature with those available in Russian economic literature and used in Russian practice. Both foreign and Russian literature have two clearly distinguished, fundamentally different positions of scientists on the considered definition. Herewith, the first group of researchers separates the terms "merger" and "acquisition", understanding by merging such a transaction between companies in which only one of the involved parties survives, usually the initiator of the transaction. The rest of the companies leave the markets (financial and commodity. This researches consider acquisition as such a process, after which the absorbed company continues to be present in the markets as a subsidiary of the company initiating the transaction. The authors justify new challenges in the M&A market, and reveal the reasons for their appearance. The article presents the genesis of the concepts of mergers and acquisitions from the point of view of their classification by essential characteristics, and reveals common features that practically all foreign and Russian researchers in this field of knowledge identify. The article also shows the distinctive features noted by scientists that expand the possibilities for business restructuring taking into account the processes of corporate control market. The authors study the classification of mergers and acquisitions with the substantiation own position on the sufficiency/insufficiency of the criterion for classifying the studied concepts to different groups; substantiate appearance of definition "transboundary mergers and

  6. Features of lipid metabolism in chronic heart failure of different genesis with concomitant overweight and obesity

    Directory of Open Access Journals (Sweden)

    Р. P. Bidzilya

    2016-08-01

    Full Text Available Recently clinical studies demonstrated reciprocal association between traditional cardiovascular risk factors, in particular, hyperlipidemia and obesity, with worse clinical outcomes in CHF. Unlike ischemic heart disease (IHD, where high levels of atherogenic and low of antiatherogenic lipids fraction traditionally associated with worsening of prognosis and course of disease, in conditions of the CHF proven negative impact of the reduction of lipid levels and body mass index. Demonstrated the phenomena called "cholesterol paradox" and "obesity paradox". Aim. To study the features of lipid metabolism in CHF of different genesis with concomitant overweight and obesity. Materials and methods. 240 patients with I–III functional class (FC of the disease with concomitant overweight and abdominal obesity I–III degree were examined. FC of the disease was established according to the classification of New York Heart Association (NYHA.Normal, overweight and the degree of abdominal obesity was identified by calculating the body mass index. Etiologic factors of CHF were chronic forms of IHD, arterial hypertension, and/or a combination of both. With the help of biochemical blood tests lipid metabolism were assessed. Results. The maximum values as atherogenic and antiatherogenic lipid indicators are investigated in non-ischemic (hypertensive CHF. Patients with CHF of ischemic genesis are characterized by minimal values of atherogenic fractions of lipids. Patients with combined etiology of CHF occupy the intermediate position of atherogenic fractions content, while they demonstrate the minimum value in the antiatherogenic HDL-cholesterol. Conclusion. Changes of lipid metabolism are varied depending on the etiology of CHF in patients with concomitant overweight and obesity and the most unfavorable in ischemic form of the disease.

  7. Divergent responses of tropical cyclone genesis factors to strong volcanic eruptions at different latitudes

    Science.gov (United States)

    Yan, Qing; Zhang, Zhongshi; Wang, Huijun

    2018-03-01

    To understand the behaviors of tropical cyclones (TCs), it is very important to explore how TCs respond to anthropogenic greenhouse gases and natural forcings. Volcanic eruptions are a major natural forcing mechanism because they inject sulphate aerosols into the stratosphere, which modulate the global climate by absorbing and scattering solar radiation. The number of Atlantic hurricanes is thought to be reduced following strong tropical eruptions, but whether the response of TCs varies with the locations of the volcanoes and the different ocean basins remains unknown. Here, we use the Community Earth System Model-Last Millennium Ensemble to investigate the response of the large-scale environmental factors that spawn TCs to strong volcanic eruptions at different latitudes. A composite analysis indicates that tropical and northern hemisphere volcanic eruptions lead to significantly unfavorable conditions for TC genesis over the whole Pacific basin and the North Atlantic during the 3 years post-eruption, relative to the preceding 3 years. Southern hemisphere volcanic eruptions result in obviously unfavorable conditions for TC formation over the southwestern Pacific, but more favorable conditions over the North Atlantic. The mean response over the Indian Ocean is generally muted and insignificant. It should be noted that volcanic eruptions impact on environmental conditions through both the direct effect (i.e. on radiative forcing) and the indirect effect (i.e. on El Niño-Southern Oscillation), which is not differentiated in this study. In addition, the spread of the TC genesis response is considerably large for each category of eruptions over each ocean basin, which is also seen in the observational/proxy-based records. This large spread is attributed to the differences in stratospheric aerosol distributions, initial states and eruption intensities, and makes the short-term forecast of TC activity following the next large eruption challenging.

  8. SOME CONSIDERATIONS CONCERNING THE ROLE OF COSMIC ENVIRONMENT IN SOIL GENESIS AND EVOLUTION

    Directory of Open Access Journals (Sweden)

    I. Munteanu

    2011-12-01

    Full Text Available The present day concept of soil is strongly connected to the terrestrial environment. Among the cosmic factors of soil genesis the energy (as light and heat provided by the Sun is by far the most important. The other outer space possible agents e.g. meteorites, comets, cosmic radiation and cosmic dust, are usually neglected or scarcely mentioned. The advancing of cosmic exploration spurred soil scientists to extend their interest upon the extraterrestrial regoliths of Earth-like planets (Mars, Venus and Moon. The concept of “Universal soil” in whose genesis the biotic factor and water are not mandatory, has been recently advanced. The first papers about “lunar soils” are already quoted in soil science literature; some also speak about “Martian soil” or “Venusian soil”. Although these seem to be mere regoliths quite different from the “terrestrial soil” (by absence of life and water one believes that they may give information about impact upon lithological material of severe environment of these planets. This paper tries to outline the cosmic destiny of the soil, to enlarge its meaning and to reveal the hidden connections that the soil has with some planetary and cosmic parameters. In cosmic vision the “soil” – either “lunar”, “martian”, or “terrestrial” – can be viewed as the interface of energy and matter exchange between the land masses of these celestial body and their cosmic environment. The role of the solar activity, extragalactic events, distance from the Sun, obliquity (tilt of Earth’s rotation axis and Earth’s orbit circularity are analyzed in connection with Quaternary glaciations and their influences upon the development of terrestrial soils. The influence of Moon is emphasized as being very important in shaping the zonal geography of the terrestrial soils.

  9. Microstructure and geochemical evidences for genesis of the Gol-Gohar iron deposit

    Directory of Open Access Journals (Sweden)

    Shahryar Mahmoudi

    2017-11-01

    Full Text Available Introduction The Gol-Gohar iron ore deposit located in 55 km South West of the city of Sirjan, in the Sanandaj-Sirjan structural zone. Sanandaj-Sirjan zone (SSZ is part of the Alpian-Hymalian orogenic belt and it is located in the west of the central Iran microplate. SSZ represented the metamorphic belt of the Zagros orogeny, that extends for 1500 km from Sirjan in the southeast to Sanandaj in the northwest of Iran (Mohajjel et al, 2003. The Gol-Gohar iron ore deposit is surrounded by a complex of igneous and metamorphic rocks mainly consisting of pelitic schists, basic schists, gneiss, amphibolite, marble, granodiorit, granite and mylonitic granite. In the early studies on the genesis of Gol-Gohr iron deposits, it was considered that sedimentary and tectonic processes were more effective in iron ore deposition. Later studies mainly confirmed a magmatic genesis for Gol-Gohar iron ore (Mucke and Golestaneh, 1982. Although some researchers argued that skarnisation process was the main cause of mineralisation (Hallaj and Jacobpor, 1991؛ Torabian, 2007, still some discussions on Gol-Gohr genesis are underway. Materials and methods – Gol-Gohar mine is divided into three blocks and several exploratory boreholes have been drilled down to 200 to 1400m depths in the third block. The representative samples were taken from exploration drill holes and outcrops around the mine. Microscopic observation (Zeiss Aksioscope in thin and polish sections show that the main ore mineral in the Gol-Gohar deposit is magnetite formed into two types with distinctive optical properties; the milky-gray magnetite (type1 named also “upper ore” and blue to brown magnetite (type2 named also “lower ore” (Mucke and Golestaneh, 1982. Mineralogy and microtectonic study were carried out on 100 thin and 30 polished sections using Zeiss research microscope. For geochemical analyses 20 samples were selected from 3 major exploration drill holes. After whole rock chemical

  10. The geochemistry of marine sediments, island arc magma genesis, and crust-mantle recycling

    International Nuclear Information System (INIS)

    Ben Othman, D.; Paris-6 Univ., 75; White, W.M.; Cornell Univ., Ithaca, NY; Patchett, J.; Arizona Univ., Tucson

    1989-01-01

    To assess the role of sediment subduction and recycling in island arc magma genesis and mantle evolution, we have determined Sr, Nd, and Pb isotope ratios and the concentrations of K, Rb, Cs, Ba, Sr, U, Th, Pb and rare earth elements in 36 modern marine sediments, including Mn nodules, biogenic oozes, and pelagic and hemipelagic clays from the Pacific, Antlantic and Indian Oceans. Sr and Nd isotope ratios and the Sr/Nd concentration ratios in sediments are such that mixing between subducted sediment on the one hand and depleted mantle or subducted oceanic crust on the other can produce mixing arrays which may pass either through or outside of the oceanic basalt Sr-Nd isotope 'mantle array'. Thus whether isotope compositions of island arc volcanics (IAV) plot inside our outside of the mantle array is not a good indication of whether or not their sources contain a subducted sediment component. The presence of subducted sediment in the sources of IAV should lead to Cs/Rb and Pb/Ce ratios which are higher than those in oceanic basalts, and Ba/Rb ratios which may be either higher or lower than oceanic basalts. Simple mixing calculations suggest that as little as a percent or so sediment in island arc magma sources can account for the observed Cs/Rb, Pb/Ce, and Ba/Rb ratios in IAV. However, it does not appear that high Ba/La ratios and negative Ce anomalies in IAV are inherited from sediment in IAV magma sources. It is more likely these features reflect fractionation of alkalis and alkaline earths from rare earths during slab dehydration and metasomatism. Pb isotope ratios in sediments from the Warton Basin south of the Sunda Arc are collinear in 208 Pb/ 204 Pb- 207 Pb/ 204 Pb- 206 Bp/ 204 Pb space with volcanics from West Sunda, but not with volcanics from the East Sunda. This collinearity is consistent with the hypothesis that sediments similar to these are being subducted to the magma genesis zone of the West Sunda Arc. (orig./WB)

  11. DETERMINING THE ELEMENTAL AND ISOTOPIC COMPOSITION OF THE PRESOLAR NEBULA FROM GENESIS DATA ANALYSIS: THE CASE OF OXYGEN.

    Science.gov (United States)

    Laming, J Martin; Heber, V S; Burnett, D S; Guan, Y; Hervig, R; Huss, G R; Jurewicz, A J G; Koeman-Shields, E C; McKeegan, K D; Nittler, L; Reisenfeld, D B; Rieck, K D; Wang, J; Wiens, R C; Woolum, D S

    2017-12-10

    We compare element and isotopic fractionations measured in solar wind samples collected by NASA's Genesis mission with those predicted from models incorporating both the ponderomotive force in the chromosphere and conservation of the first adiabatic invariant in the low corona. Generally good agreement is found, suggesting that these factors are consistent with the process of solar wind fractionation. Based on bulk wind measurements, we also consider in more detail the isotopic and elemental abundances of O. We find mild support for an O abundance in the range 8.75 - 8.83, with a value as low as 8.69 disfavored. A stronger conclusion must await solar wind regime specific measurements from the Genesis samples.

  12. A 15N-poor isotopic composition for the solar system as shown by Genesis solar wind samples.

    Science.gov (United States)

    Marty, B; Chaussidon, M; Wiens, R C; Jurewicz, A J G; Burnett, D S

    2011-06-24

    The Genesis mission sampled solar wind ions to document the elemental and isotopic compositions of the Sun and, by inference, of the protosolar nebula. Nitrogen was a key target element because the extent and origin of its isotopic variations in solar system materials remain unknown. Isotopic analysis of a Genesis Solar Wind Concentrator target material shows that implanted solar wind nitrogen has a (15)N/(14)N ratio of 2.18 ± 0.02 × 10(-3) (that is, ≈40% poorer in (15)N relative to terrestrial atmosphere). The (15)N/(14)N ratio of the protosolar nebula was 2.27 ± 0.03 × 10(-3), which is the lowest (15)N/(14)N ratio known for solar system objects. This result demonstrates the extreme nitrogen isotopic heterogeneity of the nascent solar system and accounts for the (15)N-depleted components observed in solar system reservoirs.

  13. The impact of summertime north Indian Ocean SST on tropical cyclone genesis over the western North Pacific

    Science.gov (United States)

    Zheng, Jiayu; Wu, Qiaoyan; Guo, Yipeng; Zhao, Sen

    2017-04-01

    In this study, we investigate the impact of interannual variability of boreal summertime (June-September) north Indian Ocean (NIO) sea surface temperature (SST) on the distribution of tropical cyclone (TC) genesis over the western North Pacific (WNP) using observational datasets. In the boreal summers with warm (cold) SST in the NIO, fewer (more) than normal TCs form over the entire WNP, with fewer (more) TCs forming north of 10°N and more (fewer) TCs forming south of 10°N. The warm (cold) SST in the NIO induces anomalous anticyclonic (cyclonic) vorticity north of 10°N and cyclonic (anticyclonic) vorticity south of 10°N, which contributes to the meridional seesaw-like distribution of WNP TC genesis. This study provides a new perspective to understand TC activities over the WNP and may help seasonal TC prediction.

  14. Effect of X-ray contrast agents on hemostasis and its role in the genesis of adverse reactions

    International Nuclear Information System (INIS)

    Sviridov, N.K.; Napolov, Yu.K.

    2001-01-01

    Based on available data, the effect of X-ray contrast agents (XCA) on homeostasis and its role in side reactions genesis are discussed. It is shown that the contrast agent type used can essentially affect the thrombocytes. Nonionic XCA are able to increase the thrombocytes degranulation in case of coronarography and percutaneous transluminal coronary angioplastics with release of procoagulants in vessel gap. This effect can to lead to acute thromboses and be the start of restenosis [ru

  15. Design and descriptive results of the "Growth, Exercise and Nutrition Epidemiological Study In preSchoolers": The GENESIS Study

    Directory of Open Access Journals (Sweden)

    Manios Yannis

    2006-02-01

    Full Text Available Abstract Background The Growth, Exercise and Nutrition Epidemiological Study in preSchoolers (GENESIS attempts to evaluate the food and nutrient intakes, as well as growth and development of a representative sample of Greek toddlers and preschool children. In the current work the study design, data collection procedures and some preliminary data of the GENESIS study are presented. Methods From April 2003 to July 2004, 1218 males and 1156 females 1 to 5 years old, stratified by parental educational level (Census 1999, were examined from 105 nurseries in five counties. Approximately 300 demographic, lifestyle, physical activity, dietary, anthropometrical and DNA variables have been recorded from the study population (children and parents. Results Regarding anthropometrical indices, boys were found to be taller than girls at all ages (P Conclusion The prevalence of overweight in the current preschool population is considerably high. Future but more extensive analyses of the GENESIS data will be able to reveal the interactions of the parameters leading to this phenomenon.

  16. GENESIS 1.1: A hybrid-parallel molecular dynamics simulator with enhanced sampling algorithms on multiple computational platforms.

    Science.gov (United States)

    Kobayashi, Chigusa; Jung, Jaewoon; Matsunaga, Yasuhiro; Mori, Takaharu; Ando, Tadashi; Tamura, Koichi; Kamiya, Motoshi; Sugita, Yuji

    2017-09-30

    GENeralized-Ensemble SImulation System (GENESIS) is a software package for molecular dynamics (MD) simulation of biological systems. It is designed to extend limitations in system size and accessible time scale by adopting highly parallelized schemes and enhanced conformational sampling algorithms. In this new version, GENESIS 1.1, new functions and advanced algorithms have been added. The all-atom and coarse-grained potential energy functions used in AMBER and GROMACS packages now become available in addition to CHARMM energy functions. The performance of MD simulations has been greatly improved by further optimization, multiple time-step integration, and hybrid (CPU + GPU) computing. The string method and replica-exchange umbrella sampling with flexible collective variable choice are used for finding the minimum free-energy pathway and obtaining free-energy profiles for conformational changes of a macromolecule. These new features increase the usefulness and power of GENESIS for modeling and simulation in biological research. © 2017 Wiley Periodicals, Inc. © 2017 Wiley Periodicals, Inc.

  17. A pre-burial adsorption model for the genesis of gold in the Witwatersrand

    International Nuclear Information System (INIS)

    Davidson, R.J.

    1990-01-01

    The chemistry related to the adsorption of gold and uranium onto algal biomass (activated carbon) is related to the genesis of the Witwatersrand. Detrital gold, together with cyanide solubilized as the stable aurocyanide complex. With the subsequent decomposition of the algal deposits, it is surmized that carbon-rich layers having adsorptive properties formed in the conglomerates. Under these conditions, gold (silver) in solution would be adsorbed selectively as the cyanide complex, together with uranium as the carbonate complex. The subsequent burial and compression of the gold-rich conglomerate with temperatures rising to about 400 degrees C would then have reduced the adsorbed gold to the metal in a single segregated gold-silver metal phase. An adsorption model would explain the very consistent trends in the gold-to-silver ratios of individual reefs in the Witwatersrand, which suggest an extensive hydrothermal system approaching isothermal equilibrium. Also, as gold grades increase, so silver grades generally decrease, indicating the sequential displacement of silver by gold as classically obtained with activated carbon. 11 refs., 2 figs., 1 tab

  18. Hydrogeochemistry and Genesis Analysis of Thermal and Mineral Springs in Arxan, Northeastern China

    Directory of Open Access Journals (Sweden)

    Xiaomin Gu

    2017-01-01

    Full Text Available In this work, the hydrogeochemistry and environmental isotopic compositions of thermal and mineral springs in Arxan, northeastern China, were used to assess the genesis of the thermal system hosted by deep-seated faults. The reservoir temperature was calculated using the mineral saturation index and geothermometers. According to isotopic analysis, the spring water was of meteoric origin. Sixteen springs in the Arxan geothermal system with outlet temperatures ranging from 10.9 to 41.0 °C were investigated. The water samples can be classified into four groups by using a Piper diagram. The aquifer in which the Group I and Group III samples were obtained was a shallow cold aquifer of the Jurassic system, which is related to the local groundwater system and contains HCO3–Ca·Na groundwater. The Group II and Group IV samples were recharged by deeply circulating meteoric water with HCO3–Na and HCO3·SO4–Na·Ca groundwater, respectively. The springs rise from the deep basement faults. The estimated thermal reservoir temperature is 50.9–68.8 °C, and the proportion of shallow cold water ranges from 54% to 87%. A conceptual flow model based on hydrogeochemical results and hydrogeological features is given to describe the geothermal system of the Arxan springs.

  19. A numerical study of the role of the vertical structure of vorticity during tropical cyclone genesis

    International Nuclear Information System (INIS)

    Venkatesh, T N; Mathew, Joseph

    2010-01-01

    An eight-level axisymmetric model with simple parameterizations for clouds and the atmospheric boundary layer was developed to examine the evolution of vortices that are precursors to tropical cyclones. The effect of vertical distributions of vorticity, especially that arising from a merger of mid-level vortices, was studied by us to provide support for a new vortex-merger theory of tropical cyclone genesis. The basic model was validated with the analytical results available for the spin-down of axisymmetric vortices. With the inclusion of the cloud and boundary layer parameterizations, the evolution of deep vortices into hurricanes and the subsequent decay are simulated quite well. The effects of several parameters such as the initial vortex strength, radius of maximum winds, sea-surface temperature and latitude (Coriolis parameter) on the evolution were examined. A new finding is the manner in which mid-level vortices of the same strength decay and how, on simulated merger of these mid-level vortices, the resulting vortex amplifies to hurricane strength in a realistic time frame. The importance of sea-surface temperature on the evolution of full vortices was studied and explained. Also it was found that the strength of the surface vortex determines the time taken by the deep vortex to amplify to hurricane strength.

  20. Characteristics and genesis of Rare Earth Element (REE) in western Indonesia

    Science.gov (United States)

    Handoko, A. D.; Sanjaya, E.

    2018-02-01

    Rare Earth Element (REE) has unique properties that have been used in many hightech applications. The demand of REE increased recently in the world due to its special properties. Although REE concentration in the crust is higher than gold, economically viable deposits are still rare. Reduction of REE exports by China cause increased prices of REE. Due to this condition, exploration of potential REE mines emerged. Indonesia also participates in this phenomenon, and explore the possibility of REE mines in its area. This review will discuss the characteristics and genesis of REE and its occurrence in western Indonesia; focused in Sumatera, Tin Island, and Kalimantan. The review is done based on literature research from several resources about characteristics of rare earth element in general and in the given area. The research shows that the potential REE mines can be found in several different locations in Indonesia, such as Tin Island, Sumatera, and Kalimantan. Most of them are composed of monazite, zircon, and xenotime as rare earth minerals. Monazite iss known for its elevated number of radioactive elements, so study about radioactive content and more environment friendly ore processing becomes compulsory.

  1. Hebb and Cattell: The Genesis of the Theory of Fluid and Crystallized Intelligence

    Science.gov (United States)

    Brown, Richard E.

    2016-01-01

    Raymond B. Cattell is credited with the development of the theory of fluid and crystallized intelligence. The genesis of this theory is, however, vague. Cattell, in different papers, stated that it was developed in 1940, 1941 or 1942. Carroll (1984, Multivariate Behavioral Research, 19, 300-306) noted the similarity of Cattell's theory to “Hebb's notion of two types of intelligence,” which was presented at the 1941 APA meeting, but the matter has been left at that. Correspondence between Cattell, Donald Hebb and George Humphrey of Queen's University, Kingston, Ontario, however, indicates that Cattell adopted Hebb's ideas of intelligence A and B and renamed them. This paper describes Hebb's two types of intelligence, and shows how Cattell used them to develop his ideas of crystallized and fluid intelligence. Hebb and Cattell exchanged a number of letters before Cattell's paper was rewritten in such a way that everyone was satisfied. This paper examines the work of Hebb and Cattell on intelligence, their correspondence, the development of the ideas of fluid and crystallized intelligence, and why Cattell (1943, p. 179) wrote that “Hebb has independently stated very clearly what constitutes two thirds of the present theory.” PMID:28018191

  2. The genesis, stratigraphy and age of Finnish peat deposits. Soiden syntvy, rakenne ja ikae Suomessa

    Energy Technology Data Exchange (ETDEWEB)

    Glueckert, G [Turun yliopisto (Finland). Maaperaegeologian osasto

    1986-01-01

    The genesis, stratigraphy and age of Finnish peat deposits are briefly described. Finnish peats are classified according to their botanical composition to Sphagnum, sedge (Carex) and wood peats. They form complex types of peat land: the ombrotrophic raised bogs in southern Finland and the minerotrophic open sedge (aapa) bogs in northern Finland. The structural bog types in the geological classification are mainly composed of Sphagnum and Carex peats. The raised bogs are predominantly built up of Sphagnum peat, the aapa bogs of Carex peat. The bogs are formed by paludification of lakes, of rising coasts or of low-lying forests. The thickness of peat varies from 3 to 8 m in southern Finland and from 1 to 3 m in northern Finland. The age of the bogs varies according to the uplift of land and the altitude of the bog gasin above sea level. The oldest bogs are 9500-10000 years old and formed in southern and eastern Finland on high-lying upland tracts just after the retreat of the ice at the end of the last glaciation. The geological and palaeontological development of bogs and the history of climate and vegetation can be studied and dated pollenanalytically and with the radiocarbon method.

  3. Factors associated with television viewing time in toddlers and preschoolers in Greece: the GENESIS study.

    Science.gov (United States)

    Kourlaba, Georgia; Kondaki, Katerina; Liarigkovinos, Thodoris; Manios, Yannis

    2009-06-01

    The aim of this work was to describe the television (TV) viewing time of preschoolers and to examine factors that may be associated with it. A representative sample of 2374 Greek children aged 1-5 years was examined (GENESIS study). Several anthropometric, socio-demographic and lifestyle characteristics were recorded. The mean value of children's TV viewing time was 1.32 h/day. Twenty six percent of participants spent > or =2 h/day in TV viewing. The percentage of children whose TV viewing time was longer than 2 h/day was higher in children aged 3-5 years (32.2%) than in those aged 1-2 years (11.1%). Multiple logistic regression revealed that the time parents spent viewing TV and the region of residence were significantly associated with child's TV viewing time among children aged 3-5 years. Among children aged 1-2 years, the maternal educational status, the region of residence and the maternal TV viewing time were found to be related to child's TV viewing time. The current findings suggest that almost one third of Greek preschoolers exceed the limit of 2 h/day TV viewing and that parental TV viewing time may be the most important determinant of children's TV viewing time.

  4. Obesity and television watching in preschoolers in Greece: the GENESIS study.

    Science.gov (United States)

    Manios, Yannis; Kourlaba, Georgia; Kondaki, Katerina; Grammatikaki, Evangelia; Anastasiadou, Anastasia; Roma-Giannikou, Eleytheria

    2009-11-01

    The aim of the current work was to evaluate the effect of preschoolers' television (TV) watching time on the prevalence of obesity even after controlling for their total energy intake and their physical activity status. A representative sample of 2,374 Greek children aged 1-5 years was examined ("Growth, Exercise and Nutrition Epidemiological Study in preSchoolers", GENESIS study). Children's TV watching time on a usual weekday and at a usual weekend was recorded. The overall mean of children's TV viewing time was 1.32 h/day. The majority of participants (74.0%) spent 4 h/day in front of a TV set. Overall, 65.2% of participants were normal weight, 17.2% were overweight, and the rest 17.6% were obese. The prevalence of obesity was significantly higher among those with TV viewing time >or=2 h/day (21.7%) compared to those watching TV characteristics and physical activity status) only among children aged 3-5 years. However, further adjusting for children's total energy intake revealed that the association between the TV viewing time and the probability of being obese was no longer statistically significant. On the other hand, physical activity status continued to be an independent factor of being obese. The current findings support the hypothesis that the effect of TV viewing time on childhood obesity is independent of physical activity status and may be attributed to the increased total energy intake during TV watching.

  5. A minimal model of the Atlantic Multidecadal Variability: its genesis and predictability

    Energy Technology Data Exchange (ETDEWEB)

    Ou, Hsien-Wang [Lamont-Doherty Earth Observatory of Columbia University, Department of Earth and Environmental Sciences, Palisades, NY (United States)

    2012-02-15

    Through a box model of the subpolar North Atlantic, we examine the genesis and predictability of the Atlantic Multidecadal Variability (AMV), posited as a linear perturbation sustained by the stochastic atmosphere. Postulating a density-dependent thermohaline circulation (THC), the latter would strongly differentiate the thermal and saline damping, and facilitate a negative feedback between the two fields. This negative feedback preferentially suppresses the low-frequency thermal variance to render a broad multidecadal peak bounded by the thermal and saline damping time. We offer this ''differential variance suppression'' as an alternative paradigm of the AMV in place of the ''damped oscillation'' - the latter generally not allowed by the deterministic dynamics and in any event bears no relation to the thermal peak. With the validated dynamics, we then assess the AMV predictability based on the relative entropy - a difference of the forecast and climatological probability distributions, which decays through both error growth and dynamical damping. Since the stochastic forcing is mainly in the surface heat flux, the thermal noise grows rapidly and together with its climatological variance limited by the THC-aided thermal damping, they strongly curtail the thermal predictability. The latter may be prolonged if the initial thermal and saline anomalies are of the same sign, but even rare events of less than 1% chance of occurrence yield a predictable time that is well short of a decade; we contend therefore that the AMV is in effect unpredictable. (orig.)

  6. Genesis of the "Critical-Acceleration of MOND" and Its Role in "Formation of Structures"

    Directory of Open Access Journals (Sweden)

    Tank H. K.

    2012-10-01

    Full Text Available As an attempt to explain the “flattening of galaxies rotation-curves”, Milgrom proposed a Modification of Newtonian Dynamics MOND, in which he needed a new constant of nature a 0 , termed as “critical-acceleration-of MOND”, in his best-fit empirical formula. But so far it has been an ad-hoc introduction of a new constant. Whereas this article pro- poses: (i a genesis of this constant; (ii explains its recurrences in various physical sit- uations; and (iii its role in determining the size and radii of various structures, like: the electron, the proton, the nucleus-of-atom, the globular-clusters, the spiral-galaxies, the galactic-clusters and the whole universe. In this process we get a new interpretation of “the cosmological-red-shift”, that the linear part of the cosmological-red-shift may not be due to “metric-expansion-of-space”; and even the currently-believed “accelerated- expansion” may be slowing down with time.

  7. ‘Protodesign’: The genesis of design, or a few things that changed the world

    Directory of Open Access Journals (Sweden)

    L Yu Bronzino

    2014-12-01

    Full Text Available The concept ‘design’ that has recently become popular in everyday discourse and among social scientists has not received an unambiguous interpretation. The ambiguity of the concept is due primarily to the complexity of the interpretation of very diverse social practices, the history of which can be traced to the earliest cultural practices of the humankind. This gives the design a universal character and exceptional significance: through the prism of this concept, we can trace the evolution of human culture as a whole. Thus, the study of the concept ‘design’ in the article is based on this theoretical background and emphasizes its basic feature - projectivity genetically related to the project thinking as an essential attribute of human activity. The logic of the article corresponds to the sequence of the main historical stages of the project thinking formation marked by specific inventions. Such an approach allows us to trace the evolution of the design revealing its genesis in the connection with the key moments of the industrial development and scientific and technological revolution as well as the most important social events that contributed to the development of the modern society urban environment and predetermined its social structure.

  8. Hebb and Cattell: The Genesis of the Theory of Fluid and Crystallized Intelligence.

    Science.gov (United States)

    Brown, Richard E

    2016-01-01

    Raymond B. Cattell is credited with the development of the theory of fluid and crystallized intelligence. The genesis of this theory is, however, vague. Cattell, in different papers, stated that it was developed in 1940, 1941 or 1942. Carroll (1984, Multivariate Behavioral Research, 19, 300-306) noted the similarity of Cattell's theory to "Hebb's notion of two types of intelligence," which was presented at the 1941 APA meeting, but the matter has been left at that. Correspondence between Cattell, Donald Hebb and George Humphrey of Queen's University, Kingston, Ontario, however, indicates that Cattell adopted Hebb's ideas of intelligence A and B and renamed them. This paper describes Hebb's two types of intelligence, and shows how Cattell used them to develop his ideas of crystallized and fluid intelligence. Hebb and Cattell exchanged a number of letters before Cattell's paper was rewritten in such a way that everyone was satisfied. This paper examines the work of Hebb and Cattell on intelligence, their correspondence, the development of the ideas of fluid and crystallized intelligence, and why Cattell (1943, p. 179) wrote that "Hebb has independently stated very clearly what constitutes two thirds of the present theory."

  9. THE SOMEŞAN PLATEAU LAKES: GENESIS, EVOLUTION AND TERRITORIAL REPARTITION

    Directory of Open Access Journals (Sweden)

    Victor SOROCOVSCHI

    2010-06-01

    Full Text Available The present paper analyzes the genesis of the lake depressions in the Someşan Plateau and the way they evolved in time and space, as well as the morphometric elements characteristic of the different genetic types of lakes. The natural lakes in this region are few and their dimensions are small; they generally appear solitarily and only rarely as lake complexes. In this category have been included the valley lakes, the lakes formed in abandoned meanders and the lakes formed in areas with landslides. The artificial lakes are more numerous and include several genetic types. The most representative are the remnant lakes formed in the depressions resulted from the exploitation of different construction materials (kaolin sands, lime stones and the anthropic salty lakes lakes formed in abandoned salt mines from the diapir area of the Hills of Dej. The rapid evolution of these types of lakes has been highlighted through the comparative analysis of the morphometric elements obtained on the basis of topometric and bathymetric measurements. The lakes arranged for pisciculture include several subtypes (ponds, fish ponds that have been identified and characterized for the fist time, their morphometric elements being determined using digital data bases, satellite images and detailed topometric maps.

  10. Genesis of Microstructures in Friction Stir Welding of Ti-6Al-4V

    Science.gov (United States)

    Tchein, Gnofam Jacques; Jacquin, Dimitri; Coupard, Dominique; Lacoste, Eric; Girot Mata, Franck

    2018-03-01

    This paper is focused on the genesis of microstructures in friction stir welding (FSW) of the Ti-6Al-4V alloy. Several titanium joints, initially prepared with four different preheat treatments, were processed by FSW. Detailed microstructural analyses were performed in order to investigate change in the microstructure during the process. In this work, the FSW processing allows a controlled and stable microstructure to be produced in the stirring zone, regardless of the initial heat treatment or the welding conditions. The welded material undergoes a severe thermomechanical treatment which can be divided into two steps. First, the friction in the shoulder and the plastic strain give rise to the necessary conditions to allow a continuous dynamic recrystallization of the β phase. This operation produces a fine and equiaxed β grain structure. Second, once the pin has moved away, the temperature decreases, and the material undergoes a heat treatment equivalent to air quenching. The material thus exhibits a β → β + α transformation with germination of a fine intergranular Widmanstätten phase within the ex-fully-recrystallized-β grains.

  11. Vanadium-rich ruby and sapphire within Mogok Gemfield, Myanmar: implications for gem color and genesis

    Science.gov (United States)

    Zaw, Khin; Sutherland, Lin; Yui, Tzen-Fu; Meffre, Sebastien; Thu, Kyaw

    2015-01-01

    Rubies and sapphires are of both scientific and commercial interest. These gemstones are corundum colored by transition elements within the alumina crystal lattice: Cr3+ yields red in ruby and Fe2+, Fe3+, and Ti4+ ionic interactions color sapphires. A minor ion, V3+ induces slate to purple colors and color change in some sapphires, but its role in coloring rubies remains enigmatic. Trace element and oxygen isotope composition provide genetic signatures for natural corundum and assist geographic typing. Here, we show that V can dominate chromophore contents in Mogok ruby suites. This raises implications for their color quality, enhancement treatments, geographic origin, exploration and exploitation and their comparison with rubies elsewhere. Precise LA-ICP-MS analysis of ruby and sapphire from Mogok placer and in situ deposits reveal that V can exceed 5,000 ppm, giving V/Cr, V/Fe and V/Ti ratios up to 26, 78, and 97 respectively. Such values significantly exceed those found elsewhere suggesting a localized geological control on V-rich ruby distribution. Our results demonstrate that detailed geochemical studies of ruby suites reveal that V is a potential ruby tracer, encourage comparisons of V/Cr-variation between ruby suites and widen the scope for geographic typing and genesis of ruby. This will allow more precise comparison of Asian and other ruby fields and assist confirmation of Mogok sources for rubies in historical and contemporary gems and jewelry.

  12. Vertical transfer of radionuclides in soils of different genesis after Chernobyl NPP accident

    International Nuclear Information System (INIS)

    Bakarykava, Zh.; Shagalova, E.; Zhukova, O.

    2003-01-01

    In this paper a vertical transfer of radionuclides in soils of different genesis after Chernobyl NPP accident was studied. Analysis of obtained data revealed that the main content of cesium-137 is located in 0-5 cm layer of turf-podsolic, sandy-loam and loamy soil provided the lack of their humidification, and of light un-bogged (automorphous) soil as well. Cesium-137 penetration into light un-bogged soils with that sings of surplus humidification is approximately 10 cm deep. Strontium-90 as global birth so Chernobyl origin migrates more rapidly than cesium-137 because of less strong bond with soil absorbing complex. Cesium-137 migration coefficients amounted (0.03-0.46)·10 -7 cm 2 /s for a slow component, and for the fast one (0.39-0.67)·10 -7 cm 2 /s. Strontium-90 migration coefficients in the experimented sites, amounted (0.07-0.58)·10 -7 cm 2 /s for a slow component, and for the fast one (0.64-1.28)·10 -7 cm 2 /s. (authors)

  13. The Genesis of Participatory Democracy in Brazil: a Scientific (ReConstruction

    Directory of Open Access Journals (Sweden)

    Marie-Hélène Sa Vilas Boas

    2017-04-01

    Full Text Available The rise of participatory democracy has often been explained by the renewal of collective action in Europe and Latin America. This review essay questions the 'movement-based' genesis of Brazilian participatory democracy by analyzing the idea of the state upon which it rests. It argues that the focus on social movements falls short of explaining the spread of participatory experiments, and that it rests on a simplified understanding of the dynamics of the Brazilian State prior to the 1980s. The argument is developed along three axes. First, the essay analyses how the 'classics' of Brazilian political sociology framed the early studies on participatory democracy. Second, it shows that even if the unifying notion of the state has been challenged, progress has focussed on the study of the democratic period. Third, it presents evidence that participation, as a practical category, was an integral part of the military regime's discourse and practice. Finally, the essay defines lines of investigation to reconsider the origins of participatory democracy in Brazil.

  14. Genesis of Microstructures in Friction Stir Welding of Ti-6Al-4V

    Science.gov (United States)

    Tchein, Gnofam Jacques; Jacquin, Dimitri; Coupard, Dominique; Lacoste, Eric; Girot Mata, Franck

    2018-06-01

    This paper is focused on the genesis of microstructures in friction stir welding (FSW) of the Ti-6Al-4V alloy. Several titanium joints, initially prepared with four different preheat treatments, were processed by FSW. Detailed microstructural analyses were performed in order to investigate change in the microstructure during the process. In this work, the FSW processing allows a controlled and stable microstructure to be produced in the stirring zone, regardless of the initial heat treatment or the welding conditions. The welded material undergoes a severe thermomechanical treatment which can be divided into two steps. First, the friction in the shoulder and the plastic strain give rise to the necessary conditions to allow a continuous dynamic recrystallization of the β phase. This operation produces a fine and equiaxed β grain structure. Second, once the pin has moved away, the temperature decreases, and the material undergoes a heat treatment equivalent to air quenching. The material thus exhibits a β → β + α transformation with germination of a fine intergranular Widmanstätten phase within the ex-fully-recrystallized- β grains.

  15. Building an outpatient imaging center: A case study at genesis healthcare system, part 2.

    Science.gov (United States)

    Yanci, Jim

    2006-01-01

    In the second of 2 parts, this article will focus on process improvement projects utilizing a case study at Genesis HealthCare System located in Zanesville, OH. Operational efficiency is a key step in developing a freestanding diagnostic imaging center. The process improvement projects began with an Expert Improvement Session (EIS) on the scheduling process. An EIS session is a facilitated meeting that can last anywhere from 3 hours to 2 days. Its intention is to take a group of people involved with the problem or operational process and work to understand current failures or breakdowns in the process. Recommendations are jointly developed to overcome any current deficiencies, and a work plan is structured to create ownership over the changes. A total of 11 EIS sessions occurred over the course of this project, covering 5 sections: Scheduling/telephone call process, Pre-registration, Verification/pre-certification, MRI throughput, CT throughput. Following is a single example of a project focused on the process improvement efforts. All of the process improvement projects utilized a quasi methodology of "DMAIC" (Define, Measure, Analyze, Improve, and Control).

  16. Geoprospective study of a nuclear waste repository: salt domes; Bibliographic study of their genesis

    International Nuclear Information System (INIS)

    Billaux, D.; Robelin, C.

    1985-01-01

    This report appraises, from the results of a bibliographical study, the possibility of beginning of a domal rise from the salt layer in which or above which would have been placed a repository. The physical mecanisms of salt creep are first screened, together with the factors determining their intensity and relative importance. These factors are primarily the temperature and the state of stress. Semi empirical laws are given for some mecanisms. Present knowledge about the state of the salt in the ground are then examined: we are not able to satisfactorily calculate ''in situ'' stresses, or to explain the existence of an important shear stress, that has been pointed out by most of the stress measurements. The retrospective study of the genesis of existing domes brings an insight into their correlation with sedimentary and tectonic phases. Model studies help us to interpret the distances between domes, and to explain the scale of this phenomenon. After recapitulating the various factors of some importance, we find that the probability of a dome rise from a previously static layer is low, in the time lap we are interested in (100 000 years). Such a rise would have to be triggered by important changes in the sedimentation, erosion or tectonic activity on the site

  17. Genesis Solar Wind Science Canister Components Curated as Potential Solar Wind Collectors and Reference Contamination Sources

    Science.gov (United States)

    Allton, J. H.; Gonzalez, C. P.; Allums, K. K.

    2016-01-01

    The Genesis mission collected solar wind for 27 months at Earth-Sun L1 on both passive and active collectors carried inside of a Science Canister, which was cleaned and assembled in an ISO Class 4 cleanroom prior to launch. The primary passive collectors, 271 individual hexagons and 30 half-hexagons of semiconductor materials, are described in. Since the hard landing reduced the 301 passive collectors to many thousand smaller fragments, characterization and posting in the online catalog remains a work in progress, with about 19% of the total area characterized to date. Other passive collectors, surfaces of opportunity, have been added to the online catalog. For species needing to be concentrated for precise measurement (e.g. oxygen and nitrogen isotopes) an energy-independent parabolic ion mirror focused ions onto a 6.2 cm diameter target. The target materials, as recovered after landing, are described in. The online catalog of these solar wind collectors, a work in progress, can be found at: http://curator.jsc.nasa.gov/gencatalog/index.cfm This paper describes the next step, the cataloging of pieces of the Science Canister, which were surfaces exposed to the solar wind or component materials adjacent to solar wind collectors which may have contributed contamination.

  18. Genesis of Hurricane Sandy (2012) Simulated with a Global Mesoscale Model

    Science.gov (United States)

    Shen, Bo-Wen; DeMaria, Mark; Li, J.-L. F.; Cheung, S.

    2013-01-01

    In this study, we investigate the formation predictability of Hurricane Sandy (2012) with a global mesoscale model. We first present five track and intensity forecasts of Sandy initialized at 00Z 22-26 October 2012, realistically producing its movement with a northwestward turn prior to its landfall. We then show that three experiments initialized at 00Z 16-18 October captured the genesis of Sandy with a lead time of up to 6 days and simulated reasonable evolution of Sandy's track and intensity in the next 2 day period of 18Z 21-23 October. Results suggest that the extended lead time of formation prediction is achieved by realistic simulations of multiscale processes, including (1) the interaction between an easterly wave and a low-level westerly wind belt (WWB) and (2) the appearance of the upper-level trough at 200 hPa to Sandy's northwest. The low-level WWB and upper-level trough are likely associated with a Madden-Julian Oscillation.

  19. Genesis and Maintenance of Attentional Biases: The Role of the Locus Coeruleus-Noradrenaline System

    Directory of Open Access Journals (Sweden)

    Mana R. Ehlers

    2017-01-01

    Full Text Available Emotionally arousing events are typically better remembered than mundane ones, in part because emotionally relevant aspects of our environment are prioritized in attention. Such biased attentional tuning is itself the result of associative processes through which we learn affective and motivational relevance of cues. We propose that the locus coeruleus-noradrenaline (LC-NA system plays an important role in the genesis of attentional biases through associative learning processes as well as their maintenance. We further propose that individual differences in and disruptions of the LC-NA system underlie the development of maladaptive biases linked to psychopathology. We provide support for the proposed role of the LC-NA system by first reviewing work on attentional biases in development and its link to psychopathology in relation to alterations and individual differences in NA availability. We focus on pharmacological manipulations to demonstrate the effect of a disrupted system as well as the ADRA2b polymorphism as a tool to investigate naturally occurring differences in NA availability. We next review associative learning processes that—modulated by the LC-NA system—result in such implicit attentional biases. Further, we demonstrate how NA may influence aversive and appetitive conditioning linked to anxiety disorders as well as addiction and depression.

  20. Composition, characteristics and genesis of the ferromanganese crusts and nodules from the Indian and Pacific oceans

    Science.gov (United States)

    Chen, S.; Peng, X.

    2017-12-01

    Ferromanganese crusts and nodules are considered to be one of the most important players in the geochemical cycling of the oceans. However, the lack of integrated studies affects our explicit understanding of the mineralization, characteristics and genesis of the crusts and nodules. In this study, the mineralogy, geochemistry and molecular biology in ferromanganese crusts and nodules obtained from various oceans were explored. The crusts/nodules are composed predominantly of vernadite (δ-MnO2) and amorphous Fe oxides/hydroxides. The shale normalized negative Ce-anomalies, characteristic of hydrothermal oxides, are retained in JL and TVG6. In hydrogenous oxides, the positive Ce-anomalies were found in 21V-S7 and DY119-4. The iron isotopic compositions range between -0.543 and -0.002‰ in δ56Fe IRMM14. Using molecular 16S rRNA gene techniques (clone libraries, real-time PCR) we show that nodules (JL-B and TVG6) provide a suitable habitat for prokaryotes with an abundant and diverse prokaryotic community dominated by Mn(II)-oxidizing bacteria (Pseudomonas putida GB-1). These bacteria were not detected in the crust samples (21V-S7 and DY119-4). The results suggest that a biologically driven Manganese cycle inside the nodule that may be relevant to their formation.

  1. Helium, neon, and argon composition of the solar wind as recorded in gold and other Genesis collector materials

    Science.gov (United States)

    Pepin, Robert O.; Schlutter, Dennis J.; Becker, Richard H.; Reisenfeld, Daniel B.

    2012-07-01

    We report compositions and fluxes of light noble gases in the solar wind (SW), extracted by stepped pyrolysis and amalgamation from gold collector materials carried on the Genesis Solar Wind Sample Return Mission. Results are compared with data from other laboratories on SW-He, Ne and Ar distributions implanted in Genesis aluminum, carbon, and silicon collectors and extracted by laser ablation. Corrections for mass-dependent losses (“backscatter”) of impinging SW ions due to scattering from the collector material are substantially larger for gold than for these lower atomic weight targets. We assess such losses by SRIM simulation calculations of SW backscatter from gold which are applied to the measurements to recover the composition of the incident SW. Averaged results of integrated stepped pyrolysis and single-step amalgamation measurements, with 1σ errors, are as follows: for SW-Ne and Ar isotope ratios (3He/4He was not measured), 20Ne/22Ne = 14.001 ± 0.042, 21Ne/22Ne = 0.03361 ± 0.00018, 36Ar/38Ar = 5.501 ± 0.014; for SW element ratios, 4He/20Ne = 641 ± 15, 20Ne/36Ar = 51.6 ± 0.5; and for SW fluxes in atoms cm-2 s-1 at the Genesis L1 station, 4He = 1.14 ± 0.04 × 107, 20Ne = 1.80 ± 0.06 × 104, 36Ar = 3.58 ± 0.11 × 102. Except for the 21Ne/22Ne and 20Ne/36Ar ratios, these values are in reasonable accord (within ∼1-3σ) with measurements on different collector materials reported by one or both of two other Genesis noble gas research groups. We further find, in three stepped pyrolysis experiments on gold foil, that He, Ne and Ar are released at increasing temperatures without elemental fractionation, in contrast to a pyrolytic extraction of a single non-gold collector (Al) where the release patterns point to mass-dependent thermal diffusion. The pyrolyzed gold foils exhibit enhancements, relative to sample totals, in 20Ne/22Ne and 21Ne/22Ne ratios evolved at low temperatures. The absence of elemental fractionation in pyrolytic release from gold

  2. In vivo tissue engineering: Part I. Concept genesis and guidelines for its realization.

    Science.gov (United States)

    Zdrahala, R J; Zdrahala, I J

    1999-10-01

    A loss of function of an organ often represents a life-threatening situation. Transplantations are successful, but "replacement" availability, its compatibility with the host, and subsequent healing often pose serious questions. Tissue engineering, where a carefully prepared scaffold is populated, in vitro, by cells to form an artificial organ, addresses some of the problems mentioned above. Trauma associated with the implant introduction to the host often complicates the process. The novel concept of in vivo tissue engineering which is designed to mediate the healing and tissue regeneration process by providing an in vitro formed porous, microcellular scaffold is proposed. The scaffold (part or entire organ) is then populated by cells either spontaneously (the surrounding cells will spread and populate to inhabit the scaffold) or by cellular augmentation (encapsulated cells are delivered to this in statu nascendi scaffold). Minimally traumatic arthroscopic surgery combined with a unique polymer delivery system is envisioned for the introduction of this implant to a site to be repaired. Such an approach will require the formation of polymer in-situ, in a reasonable time. The scaffold-forming polymers will be, in principle, biodegradable. We propose to utilize biodegradable polyurethane systems for in vivo tissue engineering. Diversity of their structure/property relationships, relative "ease" of their preparation, and excellent biocompatibility predetermine polyurethanes to be the materials of choice. This paper describes the genesis of this concept and potentials for its realization. It is intended to initiate and stimulate discussion among the related scientific disciplines to form a basis for this field. The synthesis, application, and biodegradation of selected polyurethanes and variety of its medical utilization will be discussed in upcoming papers.

  3. Gap Junctions Contribute to Ictal/Interictal Genesis in Human Hypothalamic Hamartomas

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    Jie Wu

    2016-06-01

    Full Text Available Human hypothalamic hamartoma (HH is a rare subcortical lesion associated with treatment-resistant epilepsy. Cellular mechanisms responsible for epileptogenesis are unknown. We hypothesized that neuronal gap junctions contribute to epileptogenesis through synchronous activity within the neuron networks in HH tissue. We studied surgically resected HH tissue with Western-blot analysis, immunohistochemistry, electron microscopy, biocytin microinjection of recorded HH neurons, and microelectrode patch clamp recordings with and without pharmacological blockade of gap junctions. Normal human hypothalamus tissue was used as a control. Western blots showed increased expression of both connexin-36 (Cx36 and connexin-43 (Cx43 in HH tissue compared with normal human mammillary body tissue. Immunohistochemistry demonstrated that Cx36 and Cx43 are expressed in HH tissue, but Cx36 was mainly expressed within neuron clusters while Cx43 was mainly expressed outside of neuron clusters. Gap-junction profiles were observed between small HH neurons with electron microscopy. Biocytin injection into single recorded small HH neurons showed labeling of adjacent neurons, which was not observed in the presence of a neuronal gap-junction blocker, mefloquine. Microelectrode field recordings from freshly resected HH slices demonstrated spontaneous ictal/interictal-like discharges in most slices. Bath-application of gap-junction blockers significantly reduced ictal/interictal-like discharges in a concentration-dependent manner, while not affecting the action-potential firing of small gamma-aminobutyric acid (GABA neurons observed with whole-cell patch-clamp recordings from the same patient's HH tissue. These results suggest that neuronal gap junctions between small GABAergic HH neurons participate in the genesis of epileptic-like discharges. Blockade of gap junctions may be a new therapeutic strategy for controlling seizure activity in HH patients.

  4. Clinical study on role of life events in genesis of neurotic disorders and depression

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    Deepanjali Medhi

    2015-07-01

    Full Text Available Background: This study was conducted to know about the role of life events in genesis of neurotic disorders and depression in four groups of patients with dissociative disorder, somatisation disorder, generalized anxiety disorder (GAD, and depression. It was conducted in the Department of Psychiatry, Gauhati Medical College and Hospital, Guwahati, Assam, India. Methods and materials: It was a case control study with 100 cases of neurotic disorders and depression (25 cases in each group attending indoor and outdoor, and diagnosed using research diagnostic criteria of the tenth revision of the International Statistical Classification of Diseases and Related Health Problems (ICD-10. The groups were compared with similar number of matched controls, in respect to number, scoring, and type of life events occurring within one year prior to the onset of illness using the Presumptive Stressful Life Events Scale (PSLES. Variables related to socio-demographic characteristics were also seen between cases and controls. Result and conclusion: Number of life events was significantly higher in depressive and generalized anxiety groups than control group. Total life events scores were significantly higher in depressive and generalized anxiety group than control group. Undesirable events were significantly higher in all groups. Personal events were significantly higher in depressives than control. Events related to interpersonal relation were significantly higher in depressive, dissociative, and GAD groups than control. Bereavement was closely associated with depression and GAD. Events related to health, finance, and education were higher in dissociative group than control. Events related to move were found significantly higher in GAD group than control. Implications of the findings are discussed.

  5. Automated calibration of TECAN genesis liquid handling workstation utilizing an online balance and density meter.

    Science.gov (United States)

    Xie, Iris H; Wang, Michael H; Carpenter, Richard; Wu, Henry Y

    2004-02-01

    With robotics widely used in bioanalytical assays, accurate system performance is essential to ensure the quality and productivity of the robotics. In our lab, an automated calibration procedure has been developed to evaluate the precision and accuracy of the TECAN (Research Triangle Park, NC, U.S.A.) Genesis liquid handling system in a bioanalytical laboratory setting. The calibrations were performed by transferring and weighing the solvents automatically on a microbalance controlled by a Gemini program. From the data acquired, calibration reports were generated using a template. The novel aspect of this approach is the use of an on-line balance and a density meter, both of which combine to make the calibration process simple, efficient, and precise. For quantitative bioanalysis, a variety of solvents, including methanol, water, mixed solvents, and plasma, are typically used to prepare standards and unknown samples. Density information is usually unknown for the mixed solvents, and the density of plasma can vary from species to species. However, with the use of a universal density meter, the density could be obtained in seconds. The issue of solvent evaporation during the calibration process was also addressed. Calibration curves were set up for various liquid classes. Pipetting volumes ranged from 10 microL to 900 microL. Precision and accuracy results obtained from the semiannual performance evaluations showed this procedure to be reliable and user-friendly. Using the automated calibration procedure, the calibration and performance evaluation of the robotic system is considerably more efficient, and the incidence of unacceptable precision and accuracy is greatly reduced.

  6. Israel state implementation and the genesis of conflict Israeli/arab

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    Luciano Kneip Zucchi

    2014-12-01

    Full Text Available We aimed to demonstrate mainly through historical analysis and international politics, the genesis of the conflict in the middle east between jews and arabs, is embedded within a global context and has its heart in imperialist interests and also the bipolarity emerged after world war ii world, and not in rivalry or hatred between secular people, although the ethnic/religious discourse has often succeeded mask the reality of this antagonism, originating in the twentieth century, which entered the xxi no prospect of resolution. history shows that, on the one hand, jews and arabs had some "conflicting interinsti'', especially at the dawn of islam, on the other hand, lived peacefully and productively for centuries, as the umayyad caliphate in spain and elsewhere. History shows that, on the one hand, Jews and Arabs had some "conflicting Interinsti'', especially at the dawn of Islam, on the other hand, lived peacefully and productively for centuries, as the Umayyad Caliphate in Spain and elsewhere. The proclamation of the State of Israel in 1948, although it had set up a compromise solution to the problem anti/Semitic in Europe, redound, however, and paradoxically, a new strangeness and new conflicts now between Jewish and Arab inhabitants of Palestine and throughout the Middle East. The European powers, in this context, flow into a contradiction that your in the same motion that reiterated their prejudices, transporting them to the Middle East and, worsening noticeably with the Cold War and the confrontation between the United States and Soviet Union, which will make region – rich in essential energy resources to the West – the scene of their confrontation, making worse a situation was already desperate in the extreme.

  7. Role of anxiety and depressive disorders in the genesis of psychosomatic disorders

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    Aleksandr Anatolyevich Shatenshtein

    2013-01-01

    Full Text Available Patients and methods. The results of clinical and psychodiagnostic examination using the Minnesota Multiphasic Personality Inventory (MMPI were analyzed in 210 therapeutic inpatients from 4 groups of psychosomatic diseases (coronary heart disease, hypertensive disease, duodenal ulcer disease, asthma, and bronchitis with an asthmatic component and 3 groups of diseases in whose genesis the psychosomatic mechanisms (pneumonia, gastritis, renal diseases played a lesser role. Healthy individuals (n=38 served as a control group. The correlation coefficients between the first scale reflecting the number of somatic complaints and the magnitude of their hypochondriacal fixation and the second one characterizing the degree of anxiety and depressive disorders were calculated within each disease group. Results. In psychosomatic diseases, the correlation coefficients between the first and second MMPI scales proved to be insignificant and substantially lower than those in the healthy individuals. This suggests that in such patients, a larger number of somatic complaints and their enhanced hypochondriacal fixation alleviate anxiety and depressive disorders, which may be regarded as an indication that there is psychosomatic defense that lessens anxiety due to a somatic disease. In somatic diseases that are not referring to as psychosomatic ones, the correlation coefficient between the first and second scales is highly significant and considerably higher than that in the healthy individuals and particularly higher than in the group of psychosomatic diseases. In the patients of these groups, an increase in anxiety and depression aggravates autonomic dysregulation reflecting in the larger number of hypochondriacal complaints. This direct relationship between autonomic functions and the level of anxiety and depression may be a risk factor for developing these disorders.

  8. The genesis of cerebellar GABAergic neurons: fate potential and specification mechanisms

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    Ketty eLeto

    2012-02-01

    Full Text Available The variety of neuronal phenotypes that populate the cerebellum derives from progenitors that proliferate in two germinal neuroepithelia: the ventricular zone generates GABAergic neurons, whereas the rhombic lip is the origin of glutamatergic types. Progenitors of the ventricular zone produce GABAergic projection neurons (Purkinje cells and nucleo-olivary neurons at the onset of cerebellar neurogenesis. Later on, however, these progenitors migrate into the prospective white matter, where they continue to divide up to postnatal development and generate different categories of inhibitory interneurons, according to precise spatio-temporal schedules. Projection neurons derive from discrete progenitor pools located in distinct microdomains of the ventricular zone, whereas interneurons originate from a single population of precursors, distinguished by the expression of the transcription factor Pax-2. Heterotopic/heterochronic transplantation experiments indicate that interneuron progenitors maintain full developmental potentialities up to the end of cerebellar development and acquire mature phenotypes under the influence of environmental cues present in the prospective white matter. Furthermore, the final fate choice occurs in postmitotic cells, rather than dividing progenitors. Extracerebellar cells grafted to the postnatal cerebellum are not responsive to local neurogenic cues and fail to adopt clear cerebellar identities. On the other hand, cerebellar cells grafted to extracerebellar regions retain typical phenotypes of cerebellar GABAergic interneurons, but acquire specific traits under the influence of local cues. These findings indicate that interneuron progenitors are multipotent and sensitive to spatio-temporally patterned environmental signals that regulate the genesis of different categories of interneurons, in precise quantities and at defined times and places.

  9. The genesis of the AIDS policy and AIDS Space in Brazil (1981-1989)

    Science.gov (United States)

    de Barros, Sandra Garrido; Vieira-da-Silva, Ligia Maria

    2016-01-01

    ABSTRACT OBJECTIVE To analyze the genesis of the policy for controlling AIDS in Brazil. METHODS Socio-historical study (1981-1989), based on Bordieu’s genetic sociology, by document analysis, bibliographical review, and in-depth interviews. It consisted of a connection between the analysis of the paths of 33 agents involved in the creation of a social space focusing on AIDS-related issues and the historical possibility conditions of the drafting of a specific policy. RESULTS AIDS Space is a gathering point for the paths of agents from several social fields (medical, scientific, political, and bureaucratic fields). A specific space for relationships, which enabled the drafting of a policy for controlling the AIDS epidemic, but also a place where the authority to talk about the meaning of the disease, the methods to prevent and treat it was under dispute. The analysis showed how the various structures (democratic administrations in Sao Paulo and at the national level, with public health officers taking important positions) and the lack of a specific therapy contributed to social agents of different ranks and backgrounds to initially set prevention as a priority. CONCLUSIONS The rise of the sanitary movement, the organization of SUS, and the dominance of the medical field at the AIDS Space contributed to foster treatment as a part of the measures to control the epidemic. These conditions allowed drafting a policy based on the integrality of care, by linking prevention and treatment in the following decade, with important participation from state bureaucracy and researchers. PMID:27463255

  10. Genesis of the gossan at the Las Cruces Ore Deposit (SW Spain). Groundwater-Rock Interaction.

    Science.gov (United States)

    Scheiber, L.; Ayora, C.; Vázquez-Suñé, E.; Soler, A.

    2016-12-01

    The Las Cruces deposit has sparked an interest in the scientific community due to the exceptional genesis and mineralogical composition. The original gossan formed by goethite and hematite has been replaced by siderite and galena rock. The current gossan composition is as the result of the interaction of groundwater that circulates through the Niebla-Posadas aquifer and a gossan formed by Fe-oxyhydroxides. The groundwater conditions promoted the reductive dissolution of Pb-bearing goethite by the organic matter degradation and the formation of siderite and galena. Hydrochemical and isotopic characteristics of groundwater endorses this hypothesis. Thus, negative Eh values, the existence of H2S and the tendency to light sulfate isotope values show the reducing conditions of groundwater. The key role of the organic matter degradation is marked by the high ammonium, boron and dissolved organic carbon (DOC) concentrations together the light δ13C values, both in groundwater and siderite. The siderite precipitation is confirmed by the high pH values (up to 10), the low amount of Fe (<10ppb) and the thermodynamic calculations. The Fe-oxyhydroxides are a high adsorption capacity which is capable of absorbing metals as arsenic, lead and antimony. The reductive dissolution of these minerals involves the release of these metal to groundwater. Then, the groundwater rich in sulfur and an excess of lead produce the galena precipitation. The likeness between the δ34S values, both the gossan and groundwater, reveals that the sulfur of the galena come from the currently groundwater. A reactive transport model confirm that the present day groundwater flux and composition is able to form the siderite rock in less than 1Ma, with no external supply of reactants. The limiting factor of the process is the Dissolved Organic Carbon (DOC) concentration in groundwater, i.e., higher concentrations would decrease the formation time, whereas the result is not sensitive to flow conditions.

  11. Genesis of textural contrasts in subsurface soil horizons in the Northern Pantanal-Brazil

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    Alexandre Ferreira do Nascimento

    2013-10-01

    Full Text Available The Pantanal region can be characterized as a quaternary floodplain with predominant sedimentation in the form of alluvial fans. In the geomorphologic and sedimentary evolution, the avulsion process is inherent to this depositional system and its dynamics, together with surface water floods, influence soil sedimentation on this plain. The knowledge and differentiation of these two events can contribute to a better understanding of the variability of soil properties and distribution under the influence of these sedimentation processes. Therefore, this study investigated the genesis of soils in the Northern Pantanal with textural contrasts in deeper horizons and their relationship with the depositional system dynamics. We analyzed four soil profiles in the region of Barão de Melgaço, Mato Grosso State, Brazil (RPPN SESC Pantanal. Two profiles were sampled near the Rio Cuiabá (AP1 and AP4 and two near the Rio São Lourenço (AP10 and AP11. In AP11, the horizons contrast in particle size between the profile basis and the surface. In AP1, AP4 and AP10, the horizons overlaying the sand layer have similar particle size properties, mainly in terms of sand distribution. In the first case, floods (surface water seem to have originated the horizons and layers with contrasting texture. In the second case, avulsion is the most pronounced process. Therefore, the two modes can form soils with contrasting texture that are discriminable by soil morphology, based on the distinct features associated to the specific sedimentation processes.

  12. Genesis of mammalian prions: from non-infectious amyloid fibrils to a transmissible prion disease.

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    Natallia Makarava

    2011-12-01

    Full Text Available The transmissible agent of prion disease consists of a prion protein in its abnormal, β-sheet rich state (PrP(Sc, which is capable of replicating itself according to the template-assisted mechanism. This mechanism postulates that the folding pattern of a newly recruited polypeptide chain accurately reproduces that of a PrP(Sc template. Here we report that authentic PrP(Sc and transmissible prion disease can be generated de novo in wild type animals by recombinant PrP (rPrP amyloid fibrils, which are structurally different from PrP(Sc and lack any detectable PrP(Sc particles. When induced by rPrP fibrils, a long silent stage that involved two serial passages preceded development of the clinical disease. Once emerged, the prion disease was characterized by unique clinical, neuropathological, and biochemical features. The long silent stage to the disease was accompanied by significant transformation in neuropathological properties and biochemical features of the proteinase K-resistant PrP material (PrPres before authentic PrP(Sc evolved. The current work illustrates that transmissible prion diseases can be induced by PrP structures different from that of authentic PrP(Sc and suggests that a new mechanism different from the classical templating exists. This new mechanism designated as "deformed templating" postulates that a change in the PrP folding pattern from the one present in rPrP fibrils to an alternative specific for PrP(Sc can occur. The current work provides important new insight into the mechanisms underlying genesis of the transmissible protein states and has numerous implications for understanding the etiology of neurodegenerative diseases.

  13. Elucidating the phenomenon of HESC-derived RPE: anatomy of cell genesis, expansion and retinal transplantation.

    Science.gov (United States)

    Vugler, Anthony; Carr, Amanda-Jayne; Lawrence, Jean; Chen, Li Li; Burrell, Kelly; Wright, Andrew; Lundh, Peter; Semo, Ma'ayan; Ahmado, Ahmad; Gias, Carlos; da Cruz, Lyndon; Moore, Harry; Andrews, Peter; Walsh, James; Coffey, Peter

    2008-12-01

    Healthy Retinal Pigment Epithelium (RPE) cells are required for proper visual function and the phenomenon of RPE derivation from Human Embryonic Stem Cells (HESC) holds great potential for the treatment of retinal diseases. However, little is known about formation, expansion and expression profile of RPE-like cells derived from HESC (HESC-RPE). By studying the genesis of pigmented foci we identified OTX1/2-positive cell types as potential HESC-RPE precursors. When pigmented foci were excised from culture, HESC-RPE expanded to form extensive monolayers, with pigmented cells at the leading edge assuming a precursor role: de-pigmenting, proliferating, expressing keratin 8 and subsequently re-differentiating. As they expanded and differentiated in vitro, HESC-RPE expressed markers of both developing and mature RPE cells which included OTX1/2, Pax6, PMEL17 and at low levels, RPE65. In vitro, without signals from a developing retinal environment, HESC-RPE could produce regular, polarised monolayers with developmentally important apical and basal features. Following transplantation of HESC-RPE into the degenerating retinal environment of Royal College of Surgeons (RCS) dystrophic rats, the cells survived in the subretinal space, where they maintained low levels of RPE65 expression and remained out of the cell cycle. The HESC-RPE cells responded to the in vivo environment by downregulating Pax6, while maintaining expression of other markers. The presence of rhodopsin-positive material within grafted HESC-RPE indicates that in the future, homogenous transplants of this cell type may be capable of supporting visual function following retinal dystrophy.

  14. Phylogenetic detection of horizontal gene transfer during the step-wise genesis of Mycobacterium tuberculosis

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    Turenne Christine

    2009-08-01

    Full Text Available Abstract Background In the past decade, the availability of complete genome sequence data has greatly facilitated comparative genomic research aimed at addressing genetic variability within species. More recently, analysis across species has become feasible, especially in genera where genome sequencing projects of multiple species have been initiated. To understand the genesis of the pathogen Mycobacterium tuberculosis within a genus where the majority of species are harmless environmental organisms, we have used genome sequence data from 16 mycobacteria to look for evidence of horizontal gene transfer (HGT associated with the emergence of pathogenesis. First, using multi-locus sequence analysis (MLSA of 20 housekeeping genes across these species, we derived a phylogeny that serves as the basis for HGT assignments. Next, we performed alignment searches for the 3989 proteins of M. tuberculosis H37Rv against 15 other mycobacterial genomes, generating a matrix of 59835 comparisons, to look for genetic elements that were uniquely found in M. tuberculosis and closely-related pathogenic mycobacteria. To assign when foreign genes were likely acquired, we designed a bioinformatic program called mycoHIT (mycobacterial homologue investigation tool to analyze these data in conjunction with the MLSA-based phylogeny. Results The bioinformatic screen predicted that 137 genes had been acquired by HGT at different phylogenetic strata; these included genes coding for metabolic functions and modification of mycobacterial lipids. For the majority of these genes, corroborating evidence of HGT was obtained, such as presence of phage or plasmid, and an aberrant GC%. Conclusion M. tuberculosis emerged through vertical inheritance along with the step-wise addition of genes acquired via HGT events, a process that may more generally describe the evolution of other pathogens.

  15. The genesis of the AIDS policy and AIDS Space in Brazil (1981-1989

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    Sandra Garrido de Barros

    2016-01-01

    Full Text Available ABSTRACT OBJECTIVE To analyze the genesis of the policy for controlling AIDS in Brazil. METHODS Socio-historical study (1981-1989, based on Bordieu’s genetic sociology, by document analysis, bibliographical review, and in-depth interviews. It consisted of a connection between the analysis of the paths of 33 agents involved in the creation of a social space focusing on AIDS-related issues and the historical possibility conditions of the drafting of a specific policy. RESULTS AIDS Space is a gathering point for the paths of agents from several social fields (medical, scientific, political, and bureaucratic fields. A specific space for relationships, which enabled the drafting of a policy for controlling the AIDS epidemic, but also a place where the authority to talk about the meaning of the disease, the methods to prevent and treat it was under dispute. The analysis showed how the various structures (democratic administrations in Sao Paulo and at the national level, with public health officers taking important positions and the lack of a specific therapy contributed to social agents of different ranks and backgrounds to initially set prevention as a priority. CONCLUSIONS The rise of the sanitary movement, the organization of SUS, and the dominance of the medical field at the AIDS Space contributed to foster treatment as a part of the measures to control the epidemic. These conditions allowed drafting a policy based on the integrality of care, by linking prevention and treatment in the following decade, with important participation from state bureaucracy and researchers.

  16. Genesis of Josephitism and functioning the opposition in “anti-Sergius” movement

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    Kamila Pawełczyk-Dura

    2015-11-01

    Full Text Available The crisis in the Russian Orthodox Church, connected with the Patriarch Tikhon’s death, initiated the deep divisions between hierarchs. Deputies of Tikhon, including dignity as a result of the nomination – which was a precedent in the canonical order of the Orthodox Church authorities – were not able to maintain the monolith community, destructed by internal divisions and persecuted by the communist state. Nomination of metropolitan of Nizhny Novogorod on the Guardian of the Patriarchal Throne and publication of The Letter (declaration of the deputy of the Guardian of the Patriarchal Throne Metropolitan Sergius (Stragorodsky of Nizhny Novgorod and the Temporary Saint Synod about the attitude of Russian Orthodox Church to the state authorities underlined differences between the faithful and the clergy. On opposite sides were followers and opponents of the Sergius’ “political line”. Activity of the last ones, manifesting in not-exchanging name of Sergius during liturgy, in moments, when words of the prayer for the superior of the local Church are being said, took the non-institutional forms of movement, definite as not-recalling. This formation, which was essentially the conglomeration of different groups of the clergy and faithful, dominated Josephites – the strongest and most active adherents of the archbishop of Leningrad Joseph (Petrovykh. Genesis those movement as a kind of symbol of opposition to the policy of servility and compromises metropolitan Sergius has been the subject of analysis of this text.

  17. Elemental Redistribution at the Onset of Soil Genesis from Basalt as Measured in a Soil Lysimeter System

    Science.gov (United States)

    Wang, Y.; Umanzor, M.; Alves Meira Neto, A.; Sengupta, A.; Amistadi, M. K.; Root, R.; Troch, P.; Chorover, J.

    2017-12-01

    Elemental translocation, resulting in enrichment or depletion relative to parent rock, is a consequence of mineral dissolution and precipitation reactions of soil genesis. Accurate measurement of translocation in natural systems is complicated by factors such as parent material heterogeneity and dust deposition. In the present work, a fully controlled and monitored 10° sloping soil lysimeter with known homogeneous initial conditions, was utilized to investigate initial stages of soil genesis from 1 m3 of crushed basalt. Throughout the two-year experiment, periodic irrigation coupled with sensor measurements enabled monitoring of changes in internal moisture states. A total 15-meter water influx resulted in distinct efflux patterns, wetting and drying cycles, as well as high volume water storage. Biological changes, such as algal and grass emergence, were visible on the soil surface, and microbial colonization throughout the profile was measured in a companion study, suggesting that biogeochemical hotspots may have formed. Forensic excavation and sampling of 324 voxels captured the final state heterogeneity of the lysimeter with respect to length and depth. Total elemental concentrations and a five-step sequential extraction (SE) scheme quantified elemental redistributions into operationally-defined pools including exchangeable, poorly-crystalline (hydr)oxides, and crystalline (hydr)oxides. Data were correlated to water flux and storage that was determined from sensor and tracer data over the two years of rock-water interaction; then used to map 2D cross-sections and identify geochemical hotspots. Total and SE Fe concentrations were used to establish a governing mass balance equation, and sub mass balance equations with unique partitioning coefficients of Fe were developed for each SE pool, respectively. The results help to explain elemental (e.g., Fe) lability and redistribution due to physical and geochemical weathering during the initial stages of soil genesis.

  18. Role of upper ocean parameters in the genesis, intensification and tracks of cyclones over the Bay of Bengal

    Digital Repository Service at National Institute of Oceanography (India)

    Maneesha, K.; Sadhuram, Y.; Prasad, K.V.S.R.

    of high heat potential (>90 kj/cm2) in the western Gulf of Mexico (Goni et al. 2003, 2009; Shay et al. 2000). Further, Hurricanes Igor (tropical Atlantic) and Celia (Eastern North Pacific), Typhoon Megi (Western North Pacific) and Cyclone Phet (Arabian Sea... 2009/10 in the Gulf of Mexico and the southwestern Pacific Ocean, while there was an increase in the western Pacific Ocean, Arabian Sea and Bay of Bengal. All the above studies emphasize the importance of the UOHC in the genesis and intensification...

  19. Dynamical peculiarities of nucleo-genesis of light nuclei on the early stage of the Universe development

    International Nuclear Information System (INIS)

    Takibaev, N.Zh.; Spanova, G.A.

    2003-01-01

    The item of the L group chemical elements nuclei generation on the early stage of the Universe development has been studied. At this stage the thermodynamical equilibrium inside of nucleus, the electromagnetic and the neutrino component are passing at adiabatic matter expand condition. Description of hot hadron substance and light nuclei nucleo-genesis process are considered in the conditions of matter thermodynamical equilibrium. The approach of thermodynamical potential and state equation were used for analysis. The reactions balance in subsystems, including isotope group and neutron medium (for example, reactions in the hydrogen group) is studied. The assessments for disintegration channel influence are given

  20. ToF-SIMS Investigation of the Effectiveness of Acid-Cleaning procedures for Genesis Solar Wind Collectors

    Science.gov (United States)

    Goreva, Y. S.; Humanyun, M.; Burnett, D. S.; Jurewicz, A. J.; Gonzalez, C. P.

    2014-01-01

    ToF-SIMS images of Genesis sample surfaces contain an incredible amount of important information, but they also show that the crash-derived surface contamination has many components, presenting a challenge to cleaning. Within the variability, we have shown that there are some samples which appear to be clean to begin with, e.g. 60471, and some are more contaminated. Samples 60493 and 60500 are a part of a focused study of the effectiveness of aqua regia and/or sulfuric acid cleaning of small flight Si implanted with Li-6 using ToF-SIMS.

  1. Interannual variability of the South Pacific Convergence Zone and implications for tropical cyclone genesis

    Energy Technology Data Exchange (ETDEWEB)

    Vincent, Emmanuel M. [IRD/UPMC/CNRS/MNHN, Laboratoire d' Oceanographie et du Climat: Experimentation et Approches Numeriques (LOCEAN), Paris (France); UPMC, LOCEAN/IPSL, Paris Cedex 05 (France); Lengaigne, Matthieu [IRD/UPMC/CNRS/MNHN, Laboratoire d' Oceanographie et du Climat: Experimentation et Approches Numeriques (LOCEAN), Paris (France); National Institute of Oceanography, Goa (India); Menkes, Christophe E. [IRD/UPMC/CNRS/MNHN, Laboratoire d' Oceanographie et du Climat: Experimentation et Approches Numeriques (LOCEAN), Paris (France); Institut de Recherche pour le Developpement, Noumea (New Caledonia); Jourdain, Nicolas C. [Institut de Recherche pour le Developpement, Noumea (New Caledonia); Marchesiello, Patrick [Institut de Recherche pour le Developpement, Noumea (New Caledonia); CNES/CNRS/UPS/IRD, Laboratoire d' Etudes en Geophysique et Oceanographie Spatiale (LEGOS), Toulouse (France); Madec, Gurvan [IRD/UPMC/CNRS/MNHN, Laboratoire d' Oceanographie et du Climat: Experimentation et Approches Numeriques (LOCEAN), Paris (France); National Oceanographic Centre, Southampton (United Kingdom)

    2011-05-15

    The interannual variability of the South Pacific Convergence Zone (SPCZ) and its influence on tropical cyclone (TC) genesis in the South Pacific are investigated using observations and ERA40 reanalysis over the 1979-2002 period. In austral summer, the SPCZ displays four typical structures at interannual timescales. The first three are characterized by a diagonal orientation of the SPCZ and account for 85% of the summer seasons. One is close to climatology and the other two exhibit a 3 northward or southward departure from the SPCZ climatological position. In contrast, the fourth one, that only encompasses three austral summer seasons (the extreme 1982/1983 and 1997/1998 El Nino events and the moderate 1991/1992 El Nino event), displays very peculiar behaviour where the SPCZ largely departs from its climatological position and is zonally oriented. Variability of the western/central Pacific equatorial sea surface temperature (SST) is shown to modulate moisture transport south of the equator, thereby strongly constraining the location of the SPCZ. The SPCZ location is also shown to strongly modulate the atmospheric circulation variability in the South Pacific with specific patterns for each class. However, independently of its wide year-to-year excursions, the SPCZ is always collocated with the zero relative vorticity at low levels while the maximum vorticity axis lies 6 to the south of the SPCZ position. This coherent atmospheric organisation in the SPCZ region is shown to constrain tropical cyclogenesis to occur preferentially within 10 south of the SPCZ location as this region combines all the large-scale atmospheric conditions that favour the breeding of TCs. This analysis also reveals that cyclogenesis in the central Pacific (in the vicinity of French Polynesia) only occurs when the SPCZ displays a zonal orientation while this observation was previously attributed to El Nino years in general. Different characteristics of El Nino Southern Oscillation (ENSO

  2. The giant Bayan Obo REE-Nb-Fe deposit, China: Controversy and ore genesis

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    Hong-Rui Fan

    2016-05-01

    Full Text Available Bayan Obo ore deposit is the largest rare-earth element (REE resource, and the second largest niobium (Nb resource in the world. Due to the complicated element/mineral compositions and involving several geological events, the REE enrichment mechanism and genesis of this giant deposit still remains intense debated. The deposit is hosted in the massive dolomite, and nearly one hundred carbonatite dykes occur in the vicinity of the deposit. The carbonatite dykes can be divided into three types from early to late: dolomite, co-existing dolomite-calcite and calcite type, corresponding to different evolutionary stages of carbonatite magmatism based on the REE and trace element data. The latter always has higher REE content. The origin of the ore-hosting dolomite at Bayan Obo has been addressed in various models, ranging from a normal sedimentary carbonate rocks to volcano-sedimentary sequence, and a large carbonatitic intrusion. More geochemical evidences show that the coarse-grained dolomite represents a Mesoproterozoic carbonatite pluton and the fine-grained dolomite resulted from the extensive REE mineralization and modification of the coarse-grained variety. The ore bodies, distributed along an E–W striking belt, occur as large lenses and underwent more intense fluoritization and fenitization. The first episode mineralization is characterized by disseminated mineralization in the dolomite. The second or main-episode is banded and/or massive mineralization, cut by the third episode consisting of aegirine-rich veins. Various dating methods gave different mineralization ages at Bayan Obo, resulting in long and hot debates. Compilation of available data suggests that the mineralization is rather variable with two peaks at ∼1400 and 440 Ma. The early mineralization peak closes in time to the intrusion of the carbonatite dykes. A significant thermal event at ca. 440 Ma resulted in the formation of late-stage veins with coarse crystals of REE

  3. Magnetite as the indicator of ore genesis for the Huangshaping polymetallic deposit, southern Hunan Province, China

    Science.gov (United States)

    Ding, T.; Ma, D.; Lu, J.; Zhang, R.

    2017-12-01

    fluids might have undergone large scale circulation, the extraction from Zn-rich metamorphic basement and Mg, Al-rich strata probably have provided abundant Mg, Al, Zn in the hydrothermal fluids where Group-1 magnetites precipitated. As a conclusion, this study suggests that the compositions of magnetites can be the proxies of ore genesis.

  4. WATER RESOURCES IN THE ROMANIAN CARPATHIANS – GENESIS, TERRITORIAL DISTRIBUTION, MANAGEMENT

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    P. GÂȘTESCU

    2014-05-01

    Full Text Available Water resources in Romanian Carpathians-genesis, territorial distribution, management. Discussing water resources in Romania implies a twofold approach: water as a sine qua non of life itself and water as an important factor for the development of the contemporary society. Lying in a temperate zone, Romania’s water resources are rather modest compared with other countries in Europe. Inland rivers span 78,905 km (referred only to the 4,864 codified watercourses at an average density: 0.38 km/km2 and an annual volume: 40.6 billion m3, which means 1,765 m3/capita. To knowledge ground waters are put at 9.62 billion m3/year, of which 6 billion can be used in optimal technological and economic conditions. According to a recent UN statistical report, Romania lists at position 21 among the 34 European. Natural lakes are replenished from precipitation and springs water every year and the reserves are estimated at around 1 billion m3/year and are of local importance for water management schemes. The Black Sea (in the Romanian sector could become a major source if sea water desalting could be economical.The water resources of the drainage network were calculated on the basis of the mean liquid flow map (scale 1: 500,000 releves picture of river-water resources in the major relief units: the Carpathian, which occupies only 27.9% of the Romanian territory, 65.3% (26.48 billion mc from a total of 40.61 billion m3 of the water is formed and regenerated every year; the hill unit, which includes the Subcarpathians, the tablelands and the piedmont hills, and occupies 42.4% of Romania’s territory, only 28.0% of the water volume is formed (11.38 billion m3, of which 8.7% (3.51 billion m3 in the Subcarpathians and 19.4% (7.87 billion m3 in the other two units; the plain unit, which covers 29.7% of the country’s territory, the water volume formed there is small (6.7%

  5. Repliek op Van der Watt se artikel oor ‘Intertekstualiteit en oorinterpretasie: Verwysings na Genesis 28:12 in Johannes 1:51?’

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    Hennie F. Stander

    2017-10-01

    Full Text Available A response to Van der Watt’s article on ‘Intertextuality and over-interpretation: References to Genesis 28:12 in John 1:51?’ This article is a response to an article of Van der Watt titled ‘Intertextuality and over-interpretation: References to Genesis 28:12 in John 1:51?’ (2016. He states in this article that his aim is ‘to illustrate the dangers of over-interpretation when dealing with intertextual relations between texts, especially when allusion is assumed’. He then gives a brief survey of different interpretations of John 1:51. Van der Watt shows in his article how theologians use themes from Genesis 28:12 (like the ladder, Jacob or Bethel, which are not mentioned in John 1:51 in their expositions of John 1:51. Van der Watt regards some of these expositions as examples of over-interpretation. The aim of my article is to show how Church Fathers interpreted Genesis 28:12 and John 1:51. I show in my article that the Church Fathers saw several parallels between these two sections from the Bible. Furthermore, I suggest that the early theologians’ interpretations formed a tradition that probably influenced modern interpreters of the Bible. I also discuss the role of typology in the history of interpretation, specifically also in the case of Genesis 28:12 and John 1:51. I then argue that it is perhaps not so far-fetched to see an intertextual relation between Genesis 28:12 and John 1:51.

  6. The added value of biomarker analysis to the genesis of Plaggic Anthrosols.

    Science.gov (United States)

    van Mourik, Jan; Jansen, Boris

    2015-04-01

    Coversands (chemical poor Late-glacial aeolian sand deposits) dominate the surface geology of an extensive area in northwestern Europe. Plaggic Anthrosols occur in cultural landscapes, developed on coversands. They are the characteristic soils that developed on ancient fertilized arable fields. Plaggic Anthrosols have a complex genesis. They are records of aspects environmental and agricultural history. In previous studies information of the soil records was unlocked by application of pollen analysis, 14C and OSL dating. In this study we applied biomarker analysis to unlock additional information about the applied organic sources in the production of plaggic manure. Radiocarbon dating suggested the start of sedentary agriculture (after a period, characterized by shifting cultivation and Celtic fields) between 3000 and 2000 BP. In previous studies is assumed that farmers applied organic sods, dug on forest soils and heath to produce organic stable manure to fertilize the fields. The mineral fraction of the sods was supposed to be responsible for the development of the plaggic horizon and the raise of the land surface. Optically stimulated Luminescence dating however suggested that plaggic deposition on the fields started relatively late, in the 18th century. The use of ectorganic matter from the forest soils must have been ended in the 10th-12th century, due to commercial forest clear cuttings as recorded in archived documents. These deforestations resulted in the first extension of sand drifting and famers had to protect the valuable heath against this ' environmental catastrophe' . The use of heath for sheep grazing and other purposes as honey production could continue till the 18th century, as recorded in archived documents. In the course of the 18th century, the population growth resulted in increasing demand for food. The deep stable economy was introduced and the booming demand for manure resulted in intensive sod digging on the heath. This caused heath

  7. [Autism and epigenetics. A model of explanation for the understanding of the genesis in autism spectrum disorders].

    Science.gov (United States)

    Arberas, Claudia; Ruggieri, Víctor

    2013-01-01

    Autism spectrum disorders are characterized by impairment of social integration and language development and restricted interests. Autism spectrum disorders manifest during childhood and may have a varying clinical expression over the years related to different therapeutic approaches, behavior-modifying drugs, and environmental factors, among others. So far, the genetic alterations identified are not sufficient to explain the genesis of all these processes, as many of the mutations found are also present in unaffected individuals. Findings on the underlying biological and pathophysiological mechanisms of entities strongly associated with autism spectrum disorders, such as Rett, fragile X, Angelman, and fetal alcohol syndromes, point to the role of epigenetic changes in disorders of neurodevelopment. Epigenetic phenomena are normal biological processes necessary for cell and thus human life, especially related to embryonic development. Different phenomena that affect epigenetic processes (changes that change operation or expression of a gene, without modifying the DNA structure) have also been shown to be important in the genesis of neurodevelopmental disorders. Alterations in the epigenetic mechanism may be reversible, which may explain the variation in the autism phenotype over time. Here we analyze the normal epigenetic mechanisms, autism spectrum disorders, their association with specific entities associated with altered epigenetic mechanisms, and possible therapeutic approaches targeting these alterations.

  8. Organizational and technological genesis as a tool for strategic planning of large-scale real estate development projects

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    Gusakova Elena

    2018-01-01

    Full Text Available Conceptual planning and implementation of large-scale real estate development projects is one of the most difficult tasks in the organization of construction. In the Russian practice, a large experience of development, complex reorganization and redevelopment of large development areas is accumulated. The methodological basis for solving similar problems is the organizational and technological genesis, which considers the development of the project during the full life cycle. An analysis of this experience allows us to talk about the formation of new and effective approaches and methods within the organizational and technological genesis. Among them, the most significant and universal approaches should be highlighted: The concept of real estate development, which explains the reasons and objective needs for project transformations during its life cycle, as well as to increase the adaptive capabilities of design decisions and the project's suitability for the most likely future changes; Development project of joint action, which is based on the balance of interests of project participants; Master planning of the life cycle stages of the project and subprojects, based on the rethinking of the theory and methods of the construction organization, and allowing rationally localized construction sites and related subprojects, while retaining the remaining development and development area beyond of the negative effect of construction for comfortable living and work.

  9. Influence of Different Patellofemoral Design Variations Based on Genesis II Total Knee Endoprosthesis on Patellofemoral Pressure and Kinematics.

    Science.gov (United States)

    Leichtle, Ulf G; Lange, Barbara; Herzog, Yvonne; Schnauffer, Peter; Leichtle, Carmen I; Wülker, Nikolaus; Lorenz, Andrea

    2017-01-01

    In total knee arthroplasty (TKA), patellofemoral groove design varies greatly and likely has a distinct influence on patellofemoral biomechanics. To analyse the selective influence, five patellofemoral design variations were developed based on Genesis II total knee endoprosthesis (original design, being completely flat, being laterally elevated, being medially elevated, and both sides elevated) and made from polyamide using rapid prototyping. Muscle-loaded knee flexion was simulated on 10 human knee specimens using a custom-made knee simulator, measuring the patellofemoral pressure distribution and tibiofemoral and patellofemoral kinematics. The measurements were carried out in the native knee as well as after TKA with the 5 design prototypes. The overall influence of the different designs on the patellofemoral kinematics was small, but we found detectable effects for mediolateral tilt ( p patellofemoral pressures, major interindividual differences were seen between the designs, which, on average, largely cancelled each other out. These results suggest that the elevation of the lateral margin of the patellofemoral groove is essential for providing mediolateral guidance, but smooth contouring as with original Genesis II design seems to be sufficient. The pronounced interindividual differences identify a need for more patellofemoral design options in TKA.

  10. Golden Genesis and the Teotonio Vilela Foundation: commercializing PV residential electrification with a not-for-profit partner

    Energy Technology Data Exchange (ETDEWEB)

    D' Addario, P.J. [International Fund for Renewable Energy and Energy Efficiency, New York, NY (United States)

    2000-11-01

    This article presents a case study of a project which provides photovoltaic-based rural electrification in the state of Alagoas in northeastern Brazil. The project, the Luz do Sol Programme (LdS), was initiated in mid-1996 by the Golden Genesis Company (Golden) and the Fundacao Teotonio Vilela (FTV). The article emphasizes some noteworthy characteristics of the project: the partnership between US commercial and Brazilian philanthropic interests; the financial aspect, a dedicated line of credit requiring only the equipment itself as security; and the local ownership and management of system operations, collections, and routine maintenance. In 1996, the Golden Genesis Company had developed a central battery charging system to bring the price of electrification within the range of the rural poor; it financed the US content of the systems, with the Bank of the Northeast of Brazil (BN) financing the Brazilian content. The article traces the long and arduous path to establish the programme, including both bureaucratic and technical challenges. These difficulties brought the project to an impasse in August of 1998, and Golden withdrew. FTV then re-negotiated the agreement with BN, changing the technical approach to individual solar home systems. This improved the situation, and the project has since enjoyed 100% loan repayment rates from the entrepreneurs. In June 1999, BP/Solarex became FTV's new commercial partner. The project currently shows promise of becoming the commercially viable programme originally envisaged by Golden, with commercial and technical decision-making at the local level. (author)

  11. Evaluation of clinical efficacy of a combined analgetic drug "Fanigan" for symptomatic treatment of patients with pain syndrome of various genesis

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    Mamchur V.Y.

    2017-04-01

    Full Text Available The authors studied the efficacy of combined drug Fanigan (paracetamol 500 mg and diclofenac sodium 50 mg (production of "Kusum Pharm" (Ukraine or "Kusum Heltker PVT. LTD" (India in tablets for symptomatic treatment of patients with pain syndrome. A pronounced clinical efficiency of its application in patients with pain syndrome of various genesis in a daily dose from 2 to 3 tablets for 3 to 7 days was established. The obtained data on the clinical efficacy of the drug. Fanigan in the treatment of patients with pain syndrome of various genesis allow to recommend it for application in wide clinical practice.

  12. Magma genesis, storage and eruption processes at Aluto volcano, Ethiopia: lessons from remote sensing, gas emissions and geochemistry

    Science.gov (United States)

    Hutchison, William; Biggs, Juliet; Mather, Tamsin; Pyle, David; Gleeson, Matthew; Lewi, Elias; Yirgu, Gezahgen; Caliro, Stefano; Chiodini, Giovanni; Fischer, Tobias

    2016-04-01

    One of the most intriguing aspects of magmatism during the transition from continental rifting to sea-floor spreading is that large silicic magmatic systems develop within the rift zone. In the Main Ethiopian Rift (MER) these silicic volcanoes not only pose a significant hazard to local populations but they also sustain major geothermal resources. Understanding the journey magma takes from source to surface beneath these volcanoes is vital for determining its eruption style and for better evaluating the geothermal resources that these complexes host. We investigate Aluto, a restless silicic volcano in the MER, and combine a wide range of geochemical and geophysical techniques to constrain magma genesis, storage and eruption processes and shed light on magmatic-hydrothermal-tectonic interactions. Magma genesis and storage processes at Aluto were evaluated using new whole-rock geochemical data from recent eruptive products. Geochemical modelling confirms that Aluto's peralkaline rhyolites, that constitute the bulk of recent erupted products, are generated from protracted fractionation (>80 %) of basalt that is compositionally similar to rift-related basalts found on the margins of the complex. Crustal melting did not play a significant role in rhyolite genesis and melt storage depths of ~5 km can reproduce almost all aspects of their geochemistry. InSAR methods were then used to investigate magma storage and fluid movement at Aluto during an episode of ground deformation that took place between 2008 and 2010. Combining new SAR imagery from different viewing geometries we identified an accelerating uplift pulse and found that source models support depths of magmatic and/or fluid intrusion at ~5 km for the uplift and shallower depths of ~4 km for the subsidence. Finally, gas samples collected on Aluto in 2014 were used to evaluate magma and fluid transport processes. Our results show that gases are predominantly emanating from major fault zones on Aluto and that they

  13. BASIC LAWS OF DISTRIBUTION AND GENESIS OF PSAMMOPHILOUS COLEOPTERA OF PONTO-CASPIAN REGION IN THE CASE OF TENEBRIONIDAE AND SCARABAEOIDEA (INSECTA: COLEOPTERA

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    M. V. Nabozhenko

    2012-01-01

    Full Text Available The paper deal with migration ways of psammophilous Tenebrionidae and Scarabaeoidea of Ponto-Caspian region since the Pliocene. Reconstruction of genesis of the fauna is made after analyses of contemporary distribution. Zoogeographical analyses of fauna showed the share of species with different distribution in 3 zoogeographical big regions and bassins of Caspian sea, Sea of Azov and Black sea.

  14. BASIC LAWS OF DISTRIBUTION AND GENESIS OF PSAMMOPHILOUS COLEOPTERA OF PONTO-CASPIAN REGION IN THE CASE OF TENEBRIONIDAE AND SCARABAEOIDEA (INSECTA: COLEOPTERA)

    OpenAIRE

    M. V. Nabozhenko; I. V. Shokhin; G. M. Abdurahmanov; A. M. Klicheva; A. V. Morakhonich; D. I. Oleinik

    2012-01-01

    The paper deal with migration ways of psammophilous Tenebrionidae and Scarabaeoidea of Ponto-Caspian region since the Pliocene. Reconstruction of genesis of the fauna is made after analyses of contemporary distribution. Zoogeographical analyses of fauna showed the share of species with different distribution in 3 zoogeographical big regions and bassins of Caspian sea, Sea of Azov and Black sea.

  15. Response of the Karst Phreatic Zone to Flood Events in a Major River (Bohemian Karst, Czech Republic) and its Implication for Cave Genesis

    Czech Academy of Sciences Publication Activity Database

    Vysoká, H.; Bruthans, J.; Žák, Karel; Mls, J.

    2012-01-01

    Roč. 74, č. 1 (2012), s. 65-81 ISSN 1090-6924 R&D Projects: GA ČR GAP210/10/1760 Institutional research plan: CEZ:AV0Z30130516 Keywords : karst * cave genesis * Bohemian Karst Subject RIV: DB - Geology ; Mineralogy Impact factor: 0.474, year: 2012

  16. Genesis of Karl Popper's EPR-like experiment and its resonance amongst the physics community in the 1980s

    Science.gov (United States)

    Del Santo, Flavio

    2018-05-01

    I present the reconstruction of the involvement of Karl Popper in the community of physicists concerned with foundations of quantum mechanics, in the 1980s. At that time Popper gave active contribution to the research in physics, of which the most significant is a new version of the EPR thought experiment, alleged to test different interpretations of quantum mechanics. The genesis of such an experiment is reconstructed in detail, and an unpublished letter by Popper is reproduced in the present paper to show that he formulated his thought experiment already two years before its first publication in 1982. The debate stimulated by the proposed experiment as well as Popper's role in the physics community throughout 1980s is here analysed in detail by means of personal correspondence and publications.

  17. Impact of global warming on tropical cyclone genesis in coupled and forced simulations: role of SST spatial anomalies

    Science.gov (United States)

    Royer, Jean-François; Chauvin, Fabrice; Daloz, Anne-Sophie

    2010-05-01

    The response of tropical cyclones (TC) activity to global warming has not yet reached a clear consensus in the Fourth Assessment Report (AR4) published by the Intergovernmental Panel on Climate Change (IPCC, 2007) or in the recent scientific literature. Observed series are neither long nor reliable enough for a statistically significant detection and attribution of past TC trends, and coupled climate models give widely divergent results for the future evolution of TC activity in the different ocean basins. The potential importance of the spatial structure of the future SST warming has been pointed out by Chauvin et al. (2006) in simulations performed at CNRM with the ARPEGE-Climat GCM. The current presentation describes a new set of simulations that have been performed with the ARPEGE-Climat model to try to understand the possible role of SST patterns in the TC cyclogenesis response in 15 CMIP3 coupled simulations analysed by Royer et al (2009). The new simulations have been performed with the atmospheric component of the ARPEGE-Climat GCM forced in 10 year simulations by the SST patterns from each of 15 CMIP3 simulations with different climate model at the end of the 21st century according to scenario A2. The TC analysis is based on the computation of a Convective Yearly Genesis Parameter (CYGP) and the Genesis Potential Index (GPI). The computed genesis indices for each of the ARPEGE-Climat forced simulations is compared with the indices computed directly from the initial coupled simulation. The influence of SST patterns can then be more easily assessed since all the ARPEGE-Climat simulations are performed with the same atmospheric model, whereas the original simulations used models with different parameterization and resolutions. The analysis shows that CYGP or GPI anomalies obtained with ARPEGE are as variable between each other as those obtained originally by the different IPCC models. The variety of SST patterns used to force ARPEGE explains a large part of

  18. [The impact of germ theory in the genesis of cancer. Consequences for surgical treatment in the victorian era].

    Science.gov (United States)

    Pereira Poza, A

    1998-01-01

    We use texts by preeminent figures in Victorian surgery at the end of the nineteenth century and information about their role in disseminating the germ theory to analyse the impact of this new etiologic element in the genesis of cancer. We trace the career of William Watson Cheyne (1852-1932), a disciple of Lister, and of many other surgeons of his generation, to outline the changes in the approach to treatment for cancer, the theoretical basis for these changes, and the role of a new conceptualization of cancer in the light of the microbial theory. This theory, among many other better-known factors, helped establish the foundation for radical surgery which became widespread in oncological treatment during the final decade of the nineteenth century.

  19. Just emotions: Reading the Sarah and Hagar narrative (Genesis 16, 21 through the lens of human dignity

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    Juliana Claassens

    2013-09-01

    Full Text Available This article seeked to read the interconnected narratives of Sarah and Hagar (Genesis 16, 21 in terms of the hermeneutical lens of human dignity. For the purpose of this article, recent studies on the performative nature of emotions, which considered the central role of emotions such as pain, disgust and hatred in shaping the lives of individuals as well as the ways in which people relate to one another, were helpful in contemplating the situations of dehumanisation faced by both Sarah and Hagar as well as the broader question regarding upholding human worth in a context of indignity. This article furthermore considered the role of emotions in a conversation on ethics and particularly the way in which the narrative offered a fruitful avenue for considering Israel�s relationship to their neighbours � a line of interpretation that holds potential for reflecting on complex interracial and interethnic relationships in today�s global context.

  20. Genesis and identity of «ACN de JP»’s foundational group (1904-1909

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    Pablo Sánchez Garrido

    2017-07-01

    Full Text Available The aim of this essay is to study the genesis of the historical «Asociación Católico-Nacional de Jóvenes Propagandistas» (later, «ACN de P» from its previous gestation and preparation in the congregation of «Luises» in Madrid, between 1904 and 1909. So the article focuses on its action throughout the organ of expression –Hojas Sueltas– and others public meetings. Likewise, this essay has brought to light the identity of all the members of the foundational group of the ACN de JP, because the complete names and biographic notes of these cofounder members was unknown. Finally, the text points out some considerations about the ideological identity of the group.

  1. On the genesis of spike-wave oscillations in a mean-field model of human thalamic and corticothalamic dynamics

    International Nuclear Information System (INIS)

    Rodrigues, Serafim; Terry, John R.; Breakspear, Michael

    2006-01-01

    In this Letter, the genesis of spike-wave activity-a hallmark of many generalized epileptic seizures-is investigated in a reduced mean-field model of human neural activity. Drawing upon brain modelling and dynamical systems theory, we demonstrate that the thalamic circuitry of the system is crucial for the generation of these abnormal rhythms, observing that the combination of inhibition from reticular nuclei and excitation from the cortical signal, interplay to generate the spike-wave oscillation. The mechanism revealed provides an explanation of why approaches based on linear stability and Heaviside approximations to the activation function have failed to explain the phenomena of spike-wave behaviour in mean-field models. A mathematical understanding of this transition is a crucial step towards relating spiking network models and mean-field approaches to human brain modelling

  2. ["Directed perception", "mood", "social reinforcement". Sketches towards the historical semantics of Ludwik Fleck's Genesis and Development of a Scientific Fact].

    Science.gov (United States)

    Bauer, Julian

    2014-01-01

    This article analyses three basic concepts of Ludwik Fleck's Genesis and Development of a Scientific Fact. It shows first that Fleck's notion of "directed perception" is closely linked to Jakob von Uexküll's writings on the "Umwelt" of animals and humans. The article then proposes to regard the epistemological debates surrounding parapsychology as an important testing ground for the Fleckian concept of „mood“ and his concomitant hypotheses about „the tenacity of systems of opinion and the harmony of illusions". It finally argues that Fleck's modification of Wilhelm Jerusalem's idea of the "social consolidation" of knowledge helps us to understand the indebtedness of Fleck towards early functionalist sociology as well as his strong belief in "specific historical laws governing the development of ideas"The historical semantics of Fleck's works hence proves that his insights are neither marginal nor revolutionary but rather deeply rooted within scientific traditions from the late 19th and early 20th centuries.

  3. Sex differences in cell genesis, hippocampal volume and behavioral outcomes in a rat model of neonatal HI.

    Science.gov (United States)

    Waddell, Jaylyn; Hanscom, Marie; Shalon Edwards, N; McKenna, Mary C; McCarthy, Margaret M

    2016-01-01

    Hypoxia-ischemia (HI) of the brain in near-term and term infants is a leading cause of infant mortality and lifelong disability but current therapeutic approaches remain limited. Males consistently display greater vulnerability to the deleterious consequences of HI in both humans and animal models. Neurogenesis increases after neonatal HI and offers a potential therapeutic target for recovery. The steroid hormone estradiol has been extensively explored as a neuroprotectant in adult models of stroke but with mixed results. Less consideration has been afforded to this naturally occurring agent in the developing brain, which has unique challenges from the adult. Using a model of term HI in the rat we have explored the impact of this insult on cell genesis in the hippocampus of males and females and the ability of estradiol treatment immediately after insult to restore function. Both short-term (3 days) and long-term (7 days) post-injury were assessed and revealed that only females had markedly increased cell genesis on the short-term but both sexes were increased long-term. A battery of behavioral tests revealed motor impairment in males and compromised episodic memory while both sexes were modestly impaired in spatial memory. Juvenile social play was also depressed in both sexes after HI. Estradiol therapy improved behavioral performance in both sexes but did not reverse a deficit in hippocampal volume ipsilateral to the insult. Thus the effects of estradiol do not appear to be via cell death or proliferation but rather involve other components of neural functioning. Published by Elsevier Inc.

  4. Sex differences in cell genesis, hippocampal volume and behavioral outcomes in a rat model of neonatal HI

    Science.gov (United States)

    Waddell, Jaylyn; Hanscom, Marie; Edwards, N. Shalon; McKenna, Mary C.; McCarthy, Margaret M.

    2015-01-01

    Hypoxia ischemia (HI) of the brain in near-term and term infants is a leading cause of infant mortality and lifelong disability but current therapeutic approaches remain limited. Males consistently display greater vulnerability to the deleterious consequences of HI in both humans and animal models. Neurogenesis increases after neonatal HI and offers a potential therapeutic target for recovery. The steroid hormone estradiol has been extensively explored as a neuroprotectant in adult models of stroke but with mixed results. Less consideration has been afforded to this naturally occurring agent in the developing brain, which has unique challenges from the adult. Using a model of term HI in the rat we have explored the impact of this insult on cell genesis in the hippocampus of males and females and the ability of estradiol treatment immediately after insult to restore function. Both short-term (3 days) and long-term (7 days) post-injury were assessed and revealed that only females had markedly increased cell genesis on the short-term but both sexes were increased long-term. A battery of behavioral tests revealed motor impairment in males and compromised episodic memory while both sexes were modestly impaired in spatial memory. Juvenile social play was also depressed in both sexes after HI. Estradiol therapy improved behavioral performance in both sexes but did not reverse a deficit in hippocampal volume ipsilateral to the insult. Thus the effects of estradiol do not appear to be via cell death or proliferation but rather involve other components of neural functioning. PMID:26376217

  5. GENESIS OF KHARKOV MUSIC CULTURE IN THE HIGHLIGHT OF THE CITY’S EDUCATION AND CONCERT LIFE FORMATION

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    Olena Kononova

    2016-02-01

    Full Text Available The article highlights the genesis of Kharkov musical culture from the late 18th to the first half of the 19th century, studying it in terms of two aspects, the formation of education and the emergence of the city’s concert life.The relevance of the research subject chosen by the author is determined by the wish to give the fullest description of the multi-layered process of formation of Kharkov musical culture which played one of the leading roles in the history of Ukrainian culture, and to acquaint the Western public with the most interesting facts of the formation and development of a reputable East-European centre. The main range of issues discussed in the article covers the period of the innitial foundation of artistic education, and its influence on the expansion and perception of music in different social circles, presenting the structures and forms of the nascent musical life of Kharkov. The section "Specific features of the Ukrainian system of education" brings out the facts which indicate the progressive tendencies in education, especially, on the territory of Sloboda Ukraine. The formation of artistic education in the religious schools of the city is covered in the section "Genesis of musical education in Kharkov". One of the most productive periods of the city’s cultivation of concert life associated with the functioning of the University is analyzed in the section "The impact of the University music activities on the city's concert going." The Conclusion emphasizes the interaction of traditional and nontraditional in the musical culture of Kharkov that was clearly manifested in the concert activities of the University, in particular, in popularization of oratorios. Furthermore, it discusses the factors which participated in the development in the field of compositional achievement as well as the performing arts and opened new perspectives in the dynamics of the artistic life of the Ukrainian city.

  6. Genesis and Development of Soils along Different Geomorphic Surfaces in Kouh Birk Area, Mehrestan City

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    Mohammad Akbar Bahoorzahi

    2017-02-01

    Full Text Available Introduction: The optimum and sustainable use of soil is only possible with correct and complete understanding of its properties. The objectives of the present research were to study 1 genesis and development of soils related to different geomorphic surfaces in Kouh Birk Area (Mehrestan City, 2 Soil classification according to Soil Taxonomy (2014 and WRB (2014 systems, and 3 physicochemical properties, clay mineralogy and micromorphology of soils. Materials and Methods: Mean annual rainfall and soil temperature in the selected location are 153.46 mm and 19.6 oC, respectively. From geological point of view, the studied area is a part of west and south west zones and Flysch zone of east Iran. Soil temperature and moisture regimes of this part are thermic and aridic, respectively. Eight representative pedons on different surfaces including rock pediment, mantled pediment, Alluvial fan and Upper terraces were selected, sampled, and described. Routine physicochemical analyses, clay mineralogy, and micromorphological observations performed on soil samples. Soil reaction, texture, electrical conductivity, calcium carbonate, and gypsum were identified. Four samples including Bt horizon of pedon 1, Bk1 horizon of pedon 4, By2 horizon of pedon 5 and Bk1 horizon of pedon 7 were selected for clay mineralogy investigations. Four slides including Mg saturated, Mg saturated treated with ethylene glycol, K saturated, and K saturated heated up to 550 oC were analyzed. A Brucker X-Ray diffractometer at 40 kV and 30 mA was used for XRD analyses. Undisturbed soil samples from Bt horizon of pedon 1, Bk2 horizon of pedon 2, Btn horizon of pedon 3, By2 horizon of pedon 5, Bk1 horizon of pedon 7, and By1 horizon of pedon 8 were selected for micromorphological observations. A vestapol resin with stearic acid and cobalt as hardener was used for soil impregnation. Bk-Pol petrographic microscope was used for micromorphology investigations. Results and Discussion: Due to

  7. The genesis of the AIDS policy and AIDS Space in Brazil (1981-1989).

    Science.gov (United States)

    Barros, Sandra Garrido de; Vieira-da-Silva, Ligia Maria

    2016-07-21

    To analyze the genesis of the policy for controlling AIDS in Brazil. Socio-historical study (1981-1989), based on Bordieu's genetic sociology, by document analysis, bibliographical review, and in-depth interviews. It consisted of a connection between the analysis of the paths of 33 agents involved in the creation of a social space focusing on AIDS-related issues and the historical possibility conditions of the drafting of a specific policy. AIDS Space is a gathering point for the paths of agents from several social fields (medical, scientific, political, and bureaucratic fields). A specific space for relationships, which enabled the drafting of a policy for controlling the AIDS epidemic, but also a place where the authority to talk about the meaning of the disease, the methods to prevent and treat it was under dispute. The analysis showed how the various structures (democratic administrations in Sao Paulo and at the national level, with public health officers taking important positions) and the lack of a specific therapy contributed to social agents of different ranks and backgrounds to initially set prevention as a priority. The rise of the sanitary movement, the organization of SUS, and the dominance of the medical field at the AIDS Space contributed to foster treatment as a part of the measures to control the epidemic. These conditions allowed drafting a policy based on the integrality of care, by linking prevention and treatment in the following decade, with important participation from state bureaucracy and researchers. Analisar a gênese da política de controle da aids no Brasil. Estudo sócio-histórico (1981-1989), orientado pela sociologia genética de Bourdieu, por meio de análise documental, revisão bibliográfica e entrevistas em profundidade. Consistiu na articulação entre a análise das trajetórias de 33 agentes envolvidos na criação de um espaço social voltado para as questões relativas à aids e as condições históricas de possibilidade

  8. Mineralogy, chemistry of magnetite and genesis of Korkora-1 iron deposit, east of Takab, NW Iran

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    Mohammad Maanijou

    2014-10-01

    , respectively. Therefore, it fits in the skarn ore deposit domain in Ni/(Cr + Mn versus Ti + V and Ca + Al + Mn versus Ti + V discrimination diagrams of iron ore deposits (Beaudoin et al., 2007. High Mn in the rock samples of Korkora-1 can be resulted from substitution of Fe+2 by Mn+2 in magnetite structure that can be a sign of hydrothermal skarn. Titanium, Mn, V and Zn show a positive correlation and Al, Cu, Mg, P, Si, Ca, Ni and Cr show a negative correlation with Fe. According to the chemistry of magnetite and plotting them on V2O5 versus TiO2 and V2O5 versus Cr2O3 diagrams, it can be recognized that the samples of Korkora-1 deposit resemble exoskarn magnetite of Goto deposit. The analysis of goethite of Korkora-1 show the amount of 2.5 to 4 wt % SiO2, 76 wt % Fe, and Ni (110 ppm without Ti and Cr in its structure. Mineralographical and geochemical evidence from ore, occurrence of iron in contact with carbonates and skarn mineralogy such as garnet, pyroxene, secondary calcite, epidote and chlorite suggest iron skarn genesis for Korkora-1 deposit. Fluids generated from intrusive bodies like diorite and quartz-diorite with variations in physicochemical conditions, produced skarn in contact with carbonates and volcanic rocks. The heat from intrusive bodies caused recrystallization of carbonates and formed marbles in the footwall of the deposit. Meteoric water has also less important contribution in the ore-forming fluids. Fluid inclusion studies show existing of two types of fluids, a low salinity (10 wt % NaCl equiv. and a medium salinity (25 to 30 wt % NaCl equiv. fluid. Mixing magmatic and meteoric waters makes decreasing in the temperatures and deposition of ore fluids. The Korkora-1 deposit formed in four stages: 1 intruding the intrusive bodies, 2 entering Fe and SiO2 into Qom carbonates and forming calc-silicates, 3 mixing magmatic and meteoric fluids, hydrolysis of calc-silicates, consuming H+, instability of Fe complexes and deposition of iron oxides, 4 retrograde

  9. The study of major, trace and rare earth elements geochemistry in Shahrestanak Mn deposit, south of Qom: Implications for genesis

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    Mohammad Maanijou

    2015-04-01

    Full Text Available Introduction The Shahrestanak Mn deposit is located in southern Qom province, 12 km southwest of the city of Kahak. Based on geological-structural divisions of Iran, the deposit belongs to central volcanic belt or Urumieh-Dokhtar zone. The Venarch deposit is one the most important known manganese deposits in Iran. The Sharestanak and Venarch deposits are spatially and temporally related to each other, and have similar geology, mineral texture and structure, host rocks, relationships with faults, and depositional environment. So, their magmatism and deposition conditions can be related to each other. Since no systematic study on the Shahrestanak deposit had been performed before discussing its geological and geochemical characteristics, here it is being attempted to study the geology, petrography, geochemistry of major, minor and trace elements, and Rare Earth Elements (REE of ore, to distinguish the depositional environments and genesis of this deposit and to compare REE of ore in this deposit with other deposits. Sampling and method of study Fourteen samples of manganese ore were selected for geochemical study and analyzing of major, minor, trace elements and REE by ICP-AES and ICP-MS and were sent to SGS Co., Toronto. Detection limits for major elements and trace elements are 0.01% and 0.05ppm, respectively. Result and discussion The deposit is characterized by various lithology and stratigraphy units, consist of: 1 Middle to -Upper Eocene volcano-sedimentary rocks, 2 Oligocene lower red conglomerate and sandstone, 3 Oligo-Miocene limestone and marl (Qom Formation, and 4 Eocene and Lower Miocene basic to intermediate dykes. The most abundant minerals of the deposit are braunite, hausmannite, pyrolusite, and manganite. Evidences such as high Mn/Fe (11.33 and Si/Al (4.86 ratios, low contents of trace elements specially Co (11.40 ppm, Ni (24 ppm, Cu (81.85 ppm, and Ce, with high amounts of SiO2, Mn, Fe, Ba, Zn, As and Sr, all represent

  10. Genesis of apocarbonatitic titanium metasomatites of the Petyayan-vara rare-earth occurrence (Vuoriyarvi, the Kola Region

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    Kozlov E. N.

    2018-03-01

    Full Text Available The objects of the study are apocarbonatitic titanium metasomatites ("titanium carbonatites" associated with the rare earth carbonatites of the Petyayan-Vara area of the Vuoriyarvi complex (the Kola region. In this paper, the following mechanism for the formation of these rocks has been substantiated based on the agreed results of mineralogical and geochemical studies. Prior to the onset of carbonatite genesis, a fluorine-enriched fluid phase originated in the lower horizons of the complex passed along the deep-permeating fracture system of several hundred meters length up to the level of the modern erosion surface. It transported Al, Fe2+, Mg, Ti, P into the pyroxenites and Si, Ca and Na out of them, as a result of which the pyroxenites were transformed into giant-grained phlogopite rocks – glimmerites. The most probable source of this fluid is alkaline aluminosilicate magma. Then carbonate melts intruded along the same fractures. In the course of carbonatite genesis, F-fluid caused a local migration of K, Al, Si, Fe, P, Ti, Nb, Ta, Zr, Hf and HREE out of glimmerites into igneous dolomite carbonatites, which led to the formation of apocarbonatitic titanium metasomatites. They represent several paragenetic associations superimposed on each other, the mineral composition and the formation sequence of which correspond to the metasomatic column zones directly observed within the contact "carbonatite – altered pyroxenite". The separation of HFSE and REE is controlled by the same metasomatic column: Ti, Nb and Ta were accumulated in titanium carbonatites, i. e. in associations of the frontal and intermediate zones, and Zr, Hf and HREE – in apatitized fields corresponding to the rear zone of the column. Accordingly, the fractionation of these elements occurred due to the "fluid – rock" interaction. Subsequently, the same long-lived fractures served as a channel for REE-Sr-Ba-S fluids, but the recrystallization caused by K

  11. GENESIS AND DEVELOPMENT OF A “NONPARTISAN” POLITICAL ACTOR: The Formation of the Jama’ah Islah Malaysia (JIM and its Roots in Western Europe

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    Sophie Lemiere

    2009-02-01

    Full Text Available This paper looks at the genesis and development of the Jama’ah Islah Malaysia (JIM, a modernist-reformist Islamist organisation that today has played a vital and visible role in the political landscape of Malaysian politics. Little is known about the early genesis of JIM, and how it began in the 1970s and 1980s as a student-based cadre organisation, created by Malaysian Muslim students studying abroad in Europe and North America. JIM’s roots therefore lie in the Islamic Representative Council (IRC that was a semi-underground student-cadre movement that was created outside Malaysia, and which aimed to bring about the Islamisation of Malaysian society through the process of social and political mobilisation. Working through the archives of JIM today and interviewing the foundermembers of JIM and the IRC, this paper is the first historical account of the formation and development of IRC and JIM to be published. 

  12. Marguerite Duras/Claude Régy: L’Amante Anglaise, the genesis of a text, the gestation of a theatre

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    Almuth Grésillon

    2013-07-01

    Full Text Available This article focuses on the genesis of the first staging of Margerite Duras’s L’Amante Anglaise, by Claude Régy, a well succeeded genesis, carried out based on the interplay between dramaturgy and the stage. Without any satisfying answer, we are facing an important theoretical issue of genetic criticism applied to theatre: is the work a dramatic text or a spectacle? Depending on the stress on the first or on the second answer, the organizing axis of the genetic dossier can be the author’s writing and all stagings of L’Amante Anglaise,forming a theoretically unified set; or the director’s notes and all of his creations. This study explores a third possibility, stipulating the indispensable intersection between both hypotheses.

  13. GENESIS: a hybrid-parallel and multi-scale molecular dynamics simulator with enhanced sampling algorithms for biomolecular and cellular simulations.

    Science.gov (United States)

    Jung, Jaewoon; Mori, Takaharu; Kobayashi, Chigusa; Matsunaga, Yasuhiro; Yoda, Takao; Feig, Michael; Sugita, Yuji

    2015-07-01

    GENESIS (Generalized-Ensemble Simulation System) is a new software package for molecular dynamics (MD) simulations of macromolecules. It has two MD simulators, called ATDYN and SPDYN. ATDYN is parallelized based on an atomic decomposition algorithm for the simulations of all-atom force-field models as well as coarse-grained Go-like models. SPDYN is highly parallelized based on a domain decomposition scheme, allowing large-scale MD simulations on supercomputers. Hybrid schemes combining OpenMP and MPI are used in both simulators to target modern multicore computer architectures. Key advantages of GENESIS are (1) the highly parallel performance of SPDYN for very large biological systems consisting of more than one million atoms and (2) the availability of various REMD algorithms (T-REMD, REUS, multi-dimensional REMD for both all-atom and Go-like models under the NVT, NPT, NPAT, and NPγT ensembles). The former is achieved by a combination of the midpoint cell method and the efficient three-dimensional Fast Fourier Transform algorithm, where the domain decomposition space is shared in real-space and reciprocal-space calculations. Other features in SPDYN, such as avoiding concurrent memory access, reducing communication times, and usage of parallel input/output files, also contribute to the performance. We show the REMD simulation results of a mixed (POPC/DMPC) lipid bilayer as a real application using GENESIS. GENESIS is released as free software under the GPLv2 licence and can be easily modified for the development of new algorithms and molecular models. WIREs Comput Mol Sci 2015, 5:310-323. doi: 10.1002/wcms.1220.

  14. Variations in large-scale tropical cyclone genesis factors over the western North Pacific in the PMIP3 last millennium simulations

    Science.gov (United States)

    Yan, Qing; Wei, Ting; Zhang, Zhongshi

    2017-02-01

    Investigation of past tropical cyclone (TC) activity in the Western North Pacific (WNP) is potentially helpful to enable better understanding of future TC behaviors. In this study, we examine variations in large-scale environmental factors important to TC genesis in the last millennium simulations from the Paleoclimate Modelling Intercomparison Project Phase 3 (PMIP3). The results show that potential intensity, a theoretical prediction of the maximum TC intensity, is increased relative to the last millennium in the north part of the WNP in the Medieval Climate Anomaly (MCA; 950-1200 AD) while it is decreased in the Little Ice Age (LIA; 1600-1850 AD). Vertical wind shear that generally inhibits TC genesis is enhanced (reduced) to the south of 20°N and is reduced (enhanced) to the north in the MCA (LIA). Relative humidity (at 600 hPa) that measures the mid-tropospheric moisture content broadly shows an increase (decrease) in the MCA (LIA). A genesis potential index indicates that conditions are generally favorable (unfavorable) for TC formation in the WNP in the MCA (LIA), especially in the northern part. Taking changes in steering flows into account, there may be an increasing (decreasing) favorability for storm strikes in East Asia in the MCA (LIA). The estimated TC activity is consistent with the geological proxies in Japan, but contradicts with the typhoon records in southern China and Taiwan. This model-data discrepancy is attributed to the limitations in both simulations and reconstructions.

  15. Genesis 2 en 3 in 1 Timoteus 2: ’n motivering vir gedrag in die erediens, die gewone lewe of die huwelik?

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    Douw G. Breed

    2006-07-01

    Full Text Available Genesis 2 and 3 in 1 Timothy 2: a rationale for conduct in public worship, ordinary life, or marriage? In his exegesis of 1 Timothy 2:1-12, Breed (2006:247-261 shows that Paul does not give any indications in this text itself of whether the instructions in verses 8-12 were aimed at regulating conduct during public worship, in ordinary life or marriage. Paul supports the instructions he gives in 1 Timothy 2:11-12 in verses 13-15 by referring to Genesis 2 and 3. This article investigates whether there is any indication in Paul’s rationale of the context in which these instructions should be read. The study focuses on Paul’s reference to the order of creation (v. 13, Eve’s temptation (v. 14a, the state of transgression in which woman finds herself and her salvation by giving birth (v. 14b-15. This study concludes that in his references to Genesis 2 and 3, Paul does not give any indications of whether this instructions in 1 Timothy 2:8-15 deals with instructions for public worship, ordinary life or marriage.

  16. Changes of Retina Are Not Involved in the Genesis of Visual Hallucinations in Parkinson’s Disease

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    Aleš Kopal

    2015-01-01

    Full Text Available Parkinson’s disease (PD is characterized by motor and nonmotor symptoms. Nonmotor symptoms include primarily visual hallucinations (VH. The aim of our study was to establish whether patients with PD and visual hallucinations (PDH+ have structural changes of retina detected by an optical coherence tomography (OCT in comparison with PD patients without visual hallucinations (PDH−. We examined 52 PD patients (18 with VH, 34 without VH and 15 age and sex matched healthy controls. Retinal nerve fiber layer (RNFL thickness and macular thickness and volume were assessed by OCT. Functional impairment of retina was assessed using 2.5% contrast sensitivity test. For OCT outcomes we analyzed 15 PDH+ and 15 PDH− subjects matched for age, gender, and PD duration. For contrast sensitivity we analyzed 8 pairs of patients matched for age, gender, and visual acuity. There was no significant difference in RNFL thickness and macular thickness and macular volume between 15 PDH+ and 15 PDH− subjects, and also between a group of 44 PD patients (both PDH+ and PDH− and 15 age and gender matched healthy controls. No significant difference was found for 2.5% contrast sensitivity test values between PDH+ and PDH− subjects. Therefore we conclude that functional and structural changes in retina play no role in genesis of VH in PD.

  17. The neural stem cell fate determinant TLX promotes tumorigenesis and genesis of cells resembling glioma stem cells.

    Science.gov (United States)

    Park, Hyo-Jung; Kim, Jun-Kyum; Jeon, Hye-Min; Oh, Se-Yeong; Kim, Sung-Hak; Nam, Do-Hyun; Kim, Hyunggee

    2010-11-01

    A growing body of evidence indicates that deregulation of stem cell fate determinants is a hallmark of many types of malignancies. The neural stem cell fate determinant TLX plays a pivotal role in neurogenesis in the adult brain by maintaining neural stem cells. Here, we report a tumorigenic role of TLX in brain tumor initiation and progression. Increased TLX expression was observed in a number of glioma cells and glioma stem cells, and correlated with poor survival of patients with gliomas. Ectopic expression of TLX in the U87MG glioma cell line and Ink4a/Arf-deficient mouse astrocytes (Ink4a/Arf(-/-) astrocytes) induced cell proliferation with a concomitant increase in cyclin D expression, and accelerated foci formation in soft agar and tumor formation in in vivo transplantation assays. Furthermore, overexpression of TLX in Ink4a/Arf(-/-) astrocytes inhibited cell migration and invasion and promoted neurosphere formation and Nestin expression, which are hallmark characteristics of glioma stem cells, under stem cell culture conditions. Our results indicate that TLX is involved in glioma stem cell genesis and represents a potential therapeutic target for this type of malignancy.

  18. Remarkable Women in a Remarkable Age. On the Genesis of the English Public Sphere, 1642-1752

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    Eleonora Cappuccilli

    2015-06-01

    Full Text Available During the era of the English Revolutions and shortly after that, some spaces, albeit limited, of female visibility open up. Thanks to the window of opportunity caused by the collapse of censorship, the participation in the radical sects and in the Civil war, some remarkable women succeed in introducing themselves in the public sphere, shaping it since its very genesis. Moreover, analysing law institutions as jointure and feoffment, the attempt is to reconstruct some fragments of juridical female autonomy, which belie the total pervasiveness of coverture in the XVII century. As in private law, in public law women, in the role of queens, gain centrality: the principle of female authority, while safeguards the holding of the monarchical regime, destabilizes its patriarchal structure. Going through the works of Katherine Chidley, Margaret Cavendish, Damaris Masham and Mary Astell, the essay aims at reconstructing women's public voice, a voice which upsets the consolidated frames and subverts the established positions, questioning the same social hierarchies.

  19. Isotopic and trace element constraints on the genesis of a boninitic sequence in the Thetford Mines ophiolitic complex, Quebec, Canada

    International Nuclear Information System (INIS)

    Olive, V.; Hebert, R.; Loubet, M.

    1997-01-01

    The Mont Ham Massif (part of the Thetford Mines ophiolite, south Quebec) represents a magmatic sequence made up of tholeiitic and boninitic derived products. A geochemical study confirms the multicomponent mixing models that have been classically advanced for the source of boninites, with slab-derived components added to the main refractory harzburgitic peridotite. An isochron diagram of the boninitic rocks is interpreted as a mixing trend between two components: (i) a light rare earth element (LREE) enriched component (A), interpreted as slab-derived fluid-melts equilibrated with sedimentary materials (ε Nd = -3, 147 Sm/ 144 Nd = 0.140), and (ii) a LREE-depleted component (B) (0.21 147 Sm/ 144 Nd Nd = 9). A multicomponent source is also necessary to explain the Nd-isotope and trace element composition of the tholeiites, which are explained by the melting of a more fertile, Iherzolitic mantle and (or) mid-ocean ridge basalt source (component C), characterized by a large-ion lithophile element depicted pattern and an lapetus mantle Nd isotopic composition (ε Nd = 9), mixed in adequate proportions with the two previously infered slab-derived components (A and B). The genesis of the boninites of Mont Ham is not significantly different from those of boninites located in the Pacific. An intraoceanic subduction zone appears to be an appropriate geodynamic environment for the Mont Ham ophiolitic sequence. (author)

  20. Cadet Education in the Imperial Russia: Genesis, Dialectics and the Role in Social Structure of the Society

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    Alexander P. Abramov

    2014-06-01

    Full Text Available The article, using historic and sociological material, presents genesis, dialectics and the role of cadet education of the imperial Russia in the social structure of the society, its weak and strong aspects, determines major stratified features of its graduates. The author notes that the realization of the practice of professional socialization in cadet corps in certain historical period is determined by the social conditions and the factors of the development of the society, its structure and environment, reproducing the modal personality of the future officer. The professional environment of the cadet education in the imperial Russia is defined as closed, line, self-organizing system. Such environment provided the graduates with high social status and prestige in different fields, defined by generic characteristics (affiliation to nobility. Along with high educational and cultural level, modal personality of the graduate is characterized by aloofness from the juniors and subordinates, individualism and careerism, certain closedness towards one’s nation and other social groups.

  1. Genesis of sandstone-type uranium deposits in the Sierra Pintada district, Mendoza, Argentina: a Moessbauer study

    International Nuclear Information System (INIS)

    Labenski, F.; Saragovi-Badler, C.

    1982-01-01

    The genesis of sandstone-type uranium deposits in the Cochico Group (Permo-Triassic) of the Sierra Pintada district, San Rafael, Mendoza, has been studied. This is the most important uranium district in Argentina. Uranium sources, uranium transport and precipitation are discussed. Uraninite and brannerite, the main uranium minerals, occur within the matrix of sandstone. Several phenomena can be deduced regarding the depositional environment. Where oxygen was available, precipitation of hydrated ferric oxides occurred; γFe 2 O 3 .nH 2 O varieties (identified by Moessbauer spectroscopy) precipitated in the upper levels of the aquifer, where CO 2 partial pressure was lower, giving reddish or reddish-brown beds. The CO 2 partial pressure also determines the distribution of biogenic agents such as bacteria. Bacteria thus find a more favourable environment for their development and action in upper levels of an aquifer. In the corresponding horizons local reduction occurred where UO 2 precipitated; therefore the highest uranium concentrations correspond to sandstone levels with reddish or reddish-brown pigment. These pigments have been identified by Moessbauer spectroscopy. (Auth.)

  2. Genesis of the North German basin - a metamorphosis model; Die Entstehung des Norddeutschen Beckens - ein Metamorphose-Modell

    Energy Technology Data Exchange (ETDEWEB)

    Brink, H.J. [ExxonMobil Production Deutschland GmbH, Hannover (Germany)

    2003-07-01

    In an integrative analysis, metamorphosis processes in the aggregated crust, potential field anomalies, the temperature field and the subsidence history are combined into a model of the genesis of the North German Basin. The model takes account of phenomena like high nitrogen concentrations in natural gases of permian sandstone and the structure of the crust and combines them with theoretical considerations. The new model for explaining geonsynclinals, in which geochemical and petrophysical processes in the lower crust have a decisive role, appears to be globally applicable. It can provide an intrinsic variant of the application of existing tectonic expansion models for explaining the subsidence of sediment basins. [German] In einer integrativen Analyse werden Metamorphoseprozesse in der aggregierten Kruste, Potentialfeldanomalien, Temperaturfeld sowie die Subsidenzgeschichte zu einem Modell fuer die Entstehung des Norddeutschen Beckens zusammengefasst, das beobachtete Phaenomene wie Stickstoffreichtum in Erdgasen permischer Sandsteine und die Struktur der Kruste mit theoretischen Ableitungen verknuepft. Das so entstandene neue Modell zur Erklaerung von Geosynklinalen, bei dem geochemisch/petrophysikalische Prozesse in der Unterkruste eine entscheidende Rolle spielen, scheint global anwendbar zu sein. Es kann die Anwendung existierender tektonischer Dehnungsmodelle zur Erklaerung der Subsidenz von Sedimentbecken um eine intrinsische Variante ergaenzen. (orig.)

  3. From an Enclosure to the Corraleja. An Analysis of the Genesis of an Ephemeral and Vernacular Colombian Architecture

    Directory of Open Access Journals (Sweden)

    Massimo Leserri

    2018-03-01

    suggests that, from long time ago, many examples of tectonic building (a set of finite or pseudo-finite elements such as branches, trunks, etc. have been nomadic, self-constructed, anonymous and with an emergency appearance which have become stable, just after many constructions, by losing all ephemeral characteristics. Likewise, to understand the Corralejas’ genesis, observing the history of European architecture has been necessary due to the several old associated experiences of transitory constructions, e.g., with recreational spaces, religious or civil celebrations. This study is based on different research methodologies such as drawings of existing cases and bibliographic and iconographic analyzes. This has also been developed through a compulsory contrast with the ancient architecture of bullfighting shows, to formulate morphological reflections and analogies and analyze their ephemeral condition. Today, the Corraleja survives in Colombia, representing an architectural oddity that must be safeguarded not only for its vernacular essence but also for its limited temporal condition. In fact, tectonics, the art of montage, reconfirms the connection allowing its existence and representing a surprising and unique set of values that must be defended and treated as an architectural heritage. After the analysis on the Corralejas genesis, the study will continue through several forms of survey to explore and define constructive aspects in a different scale of detail.

  4. GENESIS SciFlo: Choreographing Interoperable Web Services on the Grid using a Semantically-Enabled Dataflow Execution Environment

    Science.gov (United States)

    Wilson, B. D.; Manipon, G.; Xing, Z.

    2007-12-01

    The General Earth Science Investigation Suite (GENESIS) project is a NASA-sponsored partnership between the Jet Propulsion Laboratory, academia, and NASA data centers to develop a new suite of Web Services tools to facilitate multi-sensor investigations in Earth System Science. The goal of GENESIS is to enable large-scale, multi-instrument atmospheric science using combined datasets from the AIRS, MODIS, MISR, and GPS sensors. Investigations include cross-comparison of spaceborne climate sensors, cloud spectral analysis, study of upper troposphere-stratosphere water transport, study of the aerosol indirect cloud effect, and global climate model validation. The challenges are to bring together very large datasets, reformat and understand the individual instrument retrievals, co-register or re-grid the retrieved physical parameters, perform computationally-intensive data fusion and data mining operations, and accumulate complex statistics over months to years of data. To meet these challenges, we have developed a Grid computing and dataflow framework, named SciFlo, in which we are deploying a set of versatile and reusable operators for data access, subsetting, registration, mining, fusion, compression, and advanced statistical analysis. SciFlo leverages remote Web Services, called via Simple Object Access Protocol (SOAP) or REST (one-line) URLs, and the Grid Computing standards (WS-* & Globus Alliance toolkits), and enables scientists to do multi- instrument Earth Science by assembling reusable Web Services and native executables into a distributed computing flow (tree of operators). The SciFlo client & server engines optimize the execution of such distributed data flows and allow the user to transparently find and use datasets and operators without worrying about the actual location of the Grid resources. In particular, SciFlo exploits the wealth of datasets accessible by OpenGIS Consortium (OGC) Web Mapping Servers & Web Coverage Servers (WMS/WCS), and by Open Data

  5. Prediction of cesarean delivery in the term nulliparous woman: results from the prospective, multicenter Genesis study.

    Science.gov (United States)

    Burke, Naomi; Burke, Gerard; Breathnach, Fionnuala; McAuliffe, Fionnuala; Morrison, John J; Turner, Michael; Dornan, Samina; Higgins, John R; Cotter, Amanda; Geary, Michael; McParland, Peter; Daly, Sean; Cody, Fiona; Dicker, Pat; Tully, Elizabeth; Malone, Fergal D

    2017-06-01

    In contemporary practice many nulliparous women require intervention during childbirth such as operative vaginal delivery or cesarean delivery (CD). Despite the knowledge that the increasing rate of CD is associated with increasing maternal age, obesity and larger infant birthweight, we lack a reliable method to predict the requirement for such potentially hazardous obstetric procedures during labor and delivery. This issue is important, as there are greater rates of morbidity and mortality associated with unplanned CD performed in labor compared with scheduled CDs. A prediction algorithm to identify women at risk of an unplanned CD could help reduced labor associated morbidity. In this primary analysis of the Genesis study, our objective was to prospectively assess the use of prenatally determined, maternal and fetal, anthropomorphic, clinical, and ultrasound features to develop a predictive tool for unplanned CD in the term nulliparous woman, before the onset of labor. The Genesis study recruited 2336 nulliparous women with a vertex presentation between 39+0 and 40+6 weeks' gestation in a prospective multicenter national study to examine predictors of CD. At recruitment, a detailed clinical evaluation and ultrasound assessment were performed. To reduce bias from knowledge of these data potentially influencing mode of delivery, women, midwives, and obstetricians were blinded to the ultrasound data. All hypothetical prenatal risk factors for unplanned CD were assessed as a composite. Multiple logistic regression analysis and mathematical modeling was used to develop a risk evaluation tool for CD in nulliparous women. Continuous predictors were standardized using z scores. From a total enrolled cohort of 2336 nulliparous participants, 491 (21%) had an unplanned CD. Five parameters were determined to be the best combined predictors of CD. These were advancing maternal age (odds ratio [OR], 1.21; 95% confidence interval [CI], 1.09 to 1.34), shorter maternal height (OR

  6. The genesis of Jan Steens painting 'As the old ones sing, so the young ones pipe' from the Gemaeldegalerie Berlin

    International Nuclear Information System (INIS)

    Denker, A.; Kleinert, K.; Laurenze-Landsberg, C.; Reimelt, M.; Schroeder-Smeibidl, B.

    2011-01-01

    In collaboration with the research reactor of the Helmholtz-Zentrum Berlin fuer Materialien und Energie, the Gemaeldegalerie Berlin is the only institute worldwide, which systematically employs the method of Neutron-Activation-Autoradiography to analyze paintings and painting techniques. To date more than 70 paintings were investigated with this effective, non-destructive, and exceptional method. It allows the visualization of structures and layers beneath the top surface and, in addition, enables the identification of elements contained in the pigments. The instrument B8 at the research reactor BER II is dedicated to this research. Jan Steen is one of the prolific artists from the 17th century. Like other artists from that time he produced several versions of one specific topic during life-time. The topic 'As the old ones sing, so the young ones pipe' was painted by Jan Steen in 13 versions. The painting from the Gemaeldegalerie is an exception in this series as it differs in style and content from the other oeuvres. The question arises: why did the artist deviate from his usual scheme? The possible answer is provided by X-ray images and neutron autoradiographs made of the painting, allowing insight into hidden paint layers and, therefore, in the genesis of the painting. Jan Steen did not simply change the composition of the room and the figures. He originally intended an altogether different topic. Assumedly it was supposed to be a so-called merry company, located in a generous, stately room. Many pieces of this sophisticated ambiance have been eliminated from the version visible today; others were modified and integrated into the composition of the new painting. Thus, Jan Steen commenced the topic 'As the old ones sing, so the young ones pipe' from a different context.

  7. The Genesis of the Urban Culture of the Steppe of the Volga Region and Sociocultural Development of the Region

    Directory of Open Access Journals (Sweden)

    Nadezhda V. Dulina

    2016-06-01

    Full Text Available The article is devoted to the problems of the genesis of socio-historical processes of urban culture of the steppe of the Volga region, is based on historical documents, materials of scientific expeditions conducted in the lower Volga region encyclopedic scientists from the second half of the XVIII century, and the results of archaeological research here settlement sites. Based on the fact that the whole history of mankind is the history of the reference person of its economy, the authors believe that the analysis of the spaces of the modern city must be waged simultaneously in multiple coordinate systems – involving knowledge of scientific disciplines such as history and archeology, sociology, Economics etc. Attention is focused on the events in the Volga steppes of socio-economic and cultural-historical transformation, reflected in the distinctive dynamics of sociocultural development of the medieval (Khazar, the Golden Horde, Russian and modern cities in the region. The authors come to the following conclusions: the city created (and covered by most throughout the centuries (and even millennia by many generations, carry a spatial-temporal characteristics and the variety of creative ideas that make them diverse, aesthetically balanced. The growth of these cities, like all living things, inevitably threatens the time, which naturally destroys some of their historical (and in fact – "root" part to "make room" for new construction. To the relentless dynamism of our era was not able to destroy formed for many generations the idea that is subordinated to the formation and development of each particular city, you should each time from a separate historical parts of the city (or temporal-spatial "fragments" to try to reproduce it in its entirety, as the unity and integrity, while maintaining its inherent identity.

  8. Genesis Solar Wind Sample 61422: Experiment in Variation of Sequence of Cleaning Solvent for Removing Carbon-Bearing Contamination

    Science.gov (United States)

    Allton, J. H.; Kuhlman, K. R.; Allums, K. K.; Gonzalez, C. P.; Jurewicz, A. J. G.; Burnett, D. S.; Woolum, D. S.

    2015-01-01

    The recovered Genesis collector fragments are heavily contaminated with crash-derived particulate debris. However, megasonic treatment with ultra-pure-water (UPW; resistivity (is) greater than18 meg-ohm-cm) removes essentially all particulate contamination greater than 5 microns in size [e.g.1] and is thus of considerable importance. Optical imaging of Si sample 60336 revealed the presence of a large C-rich particle after UPW treatment that was not present prior to UPW. Such handling contamination is occasionally observed, but such contaminants are normally easily removed by UPW cleaning. The 60336 particle was exceptional in that, surprisingly, it was not removed by additional UPW or by hot xylene or by aqua regia treatment. It was eventually removed by treatment with NH3-H2O2. Our best interpretation of the origin of the 60336 particle was that it was adhesive from the Post-It notes used to stabilize samples for transport from Utah after the hard landing. It is possible that the insoluble nature of the 60336 particle comes from interaction of the Post-It adhesive with UPW. An occasional bit of Post-It adhesive is not a major concern, but C particulate contamination also occurs from the heat shield of the Sample Return Capsule (SRC) and this is mixed with inorganic contamination from the SRC and the Utah landing site. If UPW exposure also produced an insoluble residue from SRC C, this would be a major problem in chemical treatments to produce clean surfaces for analysis. This paper reports experiments to test whether particulate contamination was removed more easily if UPW treatment was not used.

  9. Comparative study of angio genesis radiopharmaceuticals for melanoma detection; Estudo comparativo de radiofarmacos para angiogenese na deteccao de melanoma

    Energy Technology Data Exchange (ETDEWEB)

    Oliveira, Erica Aparecida de

    2011-07-01

    Early diagnosis and treatment of melanoma, a cutaneous tumor with a serious prognosis, is extremely important for optimal clinical outcome. Phage display peptide libraries are a useful screening resource for identifying bioactive peptides that interact with cancer targets. The aim of this study was the evaluation of two technetium-99m tracers for angio genesis detection in melanoma model, using cyclic peguilated pentapeptide with RGD and NGR motifs conjugated with bifunctional chelator MAG3. The conjugated peptides (10 {mu}L of a {mu}g/{mu}L solution) were labeled with technetium-99m using a sodium tartrate buffer. Radiochemical evaluation was done by ITLC and confirmed by HPLC. Partition coefficient was determined and internalization assays were performed in two melanoma cells (B16F10 and SKMEL28). Biodistribution evaluation of the tracers was done in healthy animals at different times and also in mice bearing the tumor cells at 120 min post injection. Blocking studies were also conducted by co-injection of cold peptides. The conjugated showed the same profile in many evaluations. They were radiolabeled with high radiochemical purity (>97%). Both were hydrophilic, with preferential renal excretion. Tumor uptake was higher for human melanoma cells than for murinic melanoma cells, specially for {sup 99m}Tc-MAG3-PEG{sub 8}-c(RGDyK) (7.85{+-}{+-}2.34 %ID/g) at 120 min post injection. The performance of {sup 99m}Tc-MAG{sub 3}-PEG{sub 8}-c(RGDyk) was much better than NGR tracer concerning human melanoma uptake and might be considered in future investigations focusing radiotracers for melanoma diagnosis. (author)

  10. ISOTOPIC MASS FRACTIONATION OF SOLAR WIND: EVIDENCE FROM FAST AND SLOW SOLAR WIND COLLECTED BY THE GENESIS MISSION

    International Nuclear Information System (INIS)

    Heber, Veronika S.; Baur, Heinrich; Wieler, Rainer; Bochsler, Peter; McKeegan, Kevin D.; Neugebauer, Marcia; Reisenfeld, Daniel B.; Wiens, Roger C.

    2012-01-01

    NASA's Genesis space mission returned samples of solar wind collected over ∼2.3 years. We present elemental and isotopic compositions of He, Ne, and Ar analyzed in diamond-like carbon targets from the slow and fast solar wind collectors to investigate isotopic fractionation processes during solar wind formation. The solar wind provides information on the isotopic composition for most volatile elements for the solar atmosphere, the bulk Sun and hence, on the solar nebula from which it formed 4.6 Ga ago. Our data reveal a heavy isotope depletion in the slow solar wind compared to the fast wind composition by 63.1 ± 2.1 per mille for He, 4.2 ± 0.5 per mille amu –1 for Ne and 2.6 ± 0.5 per mille amu –1 for Ar. The three Ne isotopes suggest that isotopic fractionation processes between fast and slow solar wind are mass dependent. The He/H ratios of the collected slow and fast solar wind samples are 0.0344 and 0.0406, respectively. The inefficient Coulomb drag model reproduces the measured isotopic fractionation between fast and slow wind. Therefore, we apply this model to infer the photospheric isotopic composition of He, Ne, and Ar from our solar wind data. We also compare the isotopic composition of oxygen and nitrogen measured in the solar wind with values of early solar system condensates, probably representing solar nebula composition. We interpret the differences between these samples as being due to isotopic fractionation during solar wind formation. For both elements, the magnitude and sign of the observed differences are in good agreement with the values predicted by the inefficient Coulomb drag model.

  11. Genesis of Pb-Zn-Cu-Ag Deposits within Permian Carboniferous-Carbonate Rocks in Madina Regency, North Sumatra

    Directory of Open Access Journals (Sweden)

    Bhakti Hamonangan Harahap

    2015-09-01

    Full Text Available DOI:10.17014/ijog.2.3.167-184Strong mineralized carbonate rock-bearing Pb-Zn-Cu-Ag-(Au ores are well exposed on the Latong River area, Madina Regency, North Sumatra Province. The ore deposit is hosted within the carbonate rocks of the Permian to Carboniferous Tapanuli Group. It is mainly accumulated in hollows replacing limestone in the forms of lensoidal, colloform, veins, veinlets, cavity filling, breccia, and dissemination. The ores dominantly consist of galena (126 000 ppm Pb and sphalerite (2347 ppm Zn. The other minerals are silver, azurite, covellite, pyrite, marcasite, and chalcopyrite. This deposit was formed by at least three phases of mineralization, i.e. pyrite and then galena replaced pyrite, sphalerite replaced galena, and pyrite. The last phase is the deposition of chalcopyrite that replaced sphalerite. The Latong sulfide ore deposits posses Pb isotope ratio of 206Pb/204Pb = 19.16 - 20.72, 207Pb/204Pb = 16.16 - 17.29, and 208Pb/204Pb = 42.92 - 40.78. The characteristic feature of the deposit indicates that it is formed by a sedimentary process rather than an igneous activity in origin. This leads to an interpretation that the Latong deposit belongs to the Sedimentary Hosted Massive Sulfide (SHMS of Mississippi Valley-Type (MVT. The presence of SHMS in the island arc such as Sumatra has become controversial. For a long time, ore deposits in the Indonesian Island Arc are always identical with the porphyry and hydrothermal processes related to arc magmatism. This paper is dealing with the geology of Latong and its base metal deposits. This work is also to interpret their genesis as well as general relationship to the regional geology and tectonic setting of Sumatra.

  12. Caspase-1 is involved in the genesis of inflammatory hypernociception by contributing to peripheral IL-1β maturation

    Directory of Open Access Journals (Sweden)

    Zamboni Dario S

    2010-10-01

    Full Text Available Abstract Background Caspase-1 is a cysteine protease responsible for the processing and secretion of IL-1β and IL-18, which are closely related to the induction of inflammation. However, limited evidence addresses the participation of caspase-1 in inflammatory pain. Here, we investigated the role of caspase-1 in inflammatory hypernociception (a decrease in the nociceptive threshold using caspase-1 deficient mice (casp1-/-. Results Mechanical inflammatory hypernociception was evaluated using an electronic version of the von Frey test. The production of cytokines, PGE2 and neutrophil migration were evaluated by ELISA, radioimmunoassay and myeloperoxidase activity, respectively. The interleukin (IL-1β and cyclooxygenase (COX-2 protein expression were evaluated by western blotting. The mechanical hypernociception induced by intraplantar injection of carrageenin, tumour necrosis factor (TNFα and CXCL1/KC was reduced in casp1-/- mice compared with WT mice. However, the hypernociception induced by IL-1β and PGE2 did not differ in WT and casp1-/- mice. Carrageenin-induced TNF-α and CXCL1/KC production and neutrophil recruitment in the paws of WT mice were not different from casp1-/- mice, while the maturation of IL-1β was reduced in casp1-/- mice. Furthermore, carrageenin induced an increase in the expression of COX-2 and PGE2 production in the paw of WT mice, but was reduced in casp1-/- mice. Conclusion These results suggest that caspase-1 plays a critical role in the cascade of events involved in the genesis of inflammatory hypernociception by promoting IL-1β maturation. Because caspase-1 is involved in the induction of COX-2 expression and PGE2 production, our data support the assertion that caspase-1 is a key target to control inflammatory pain.

  13. Petrography, Geochemistry and Proposed Genesis of Ordovician Oolitic Iron Formation Members of the Lashkarak Formation, Eastern Alborz

    International Nuclear Information System (INIS)

    Maghsoudloo Mahalli, M.; Shafiei Bafti, B.

    2016-01-01

    Mineralogical characteristics combined with geochemical data show that anomalous values of Fe in studied carbonate argillite formations with respect to common sedimentary rocks are related to the abundance of iron-bearing oolites as oxides such as hematite and goethite, and the clay mineral chamosite. Based on Fe, Mg and Ca concentrations, oolitic iron formations can be divided into low-grade and high-grade iron formations. The former is characterized by chamosite and calcite, whereas the latter consists ofhematite and calcite. This research, along with available paleo-geographic and sedimentological information suggests that the iron for the formation of iron oolites was available from normal sea water and Fe could be carried as clastic particles along with clays or coating of clay particles derived from weathering and erosion of shales from adjacent land. High contents of K and Si in oolitic iron horizons, the presence of detrital zircon, quartz and clay minerals within oolites and also in the matrix of these rocks confirm the proposed model and show the important role of Fe-bearing clay minerals in the genesis of the primary chamositic oolites in an environment with p H=5-9 and medium-weak redox conditions (Maynard, 1983; Maynard, 1986). The abundance of hematite relative to goethite in the Fe-oolites, dense and elliptical oolites as well as the frequent occurrence of calcite veinlets cutting oolite beds has been attributed to diagenetic processes and the modification of chamosite and goethite to hematite. Our findings indicate that the studied members can be classified as low-grade oolitic iron formation (average 21 wt.% Fe) which do not have economic importance at present.

  14. ISOTOPIC MASS FRACTIONATION OF SOLAR WIND: EVIDENCE FROM FAST AND SLOW SOLAR WIND COLLECTED BY THE GENESIS MISSION

    Energy Technology Data Exchange (ETDEWEB)

    Heber, Veronika S.; Baur, Heinrich; Wieler, Rainer [Institute for Geochemistry and Petrology, ETH Zurich, Clausiusstrasse 25, CH-8092 Zurich (Switzerland); Bochsler, Peter [Physikalisches Institut, Universitaet Bern, Sidlerstasse 5, CH-3012 Bern (Switzerland); McKeegan, Kevin D. [Department of Earth and Space Sciences, University of California Los Angeles, 595 Charles Young Drive East, Box 951567, Los Angeles, CA 90095-1567 (United States); Neugebauer, Marcia [Lunar and Planetary Laboratory, University of Arizona, Tucson, AZ 85721-0092 (United States); Reisenfeld, Daniel B. [Department of Physics and Astronomy, University of Montana, Missoula, MT 59812 (United States); Wiens, Roger C., E-mail: heber@ess.ucla.edu [Los Alamos National Laboratory, Los Alamos, NM 87545 (United States)

    2012-11-10

    NASA's Genesis space mission returned samples of solar wind collected over {approx}2.3 years. We present elemental and isotopic compositions of He, Ne, and Ar analyzed in diamond-like carbon targets from the slow and fast solar wind collectors to investigate isotopic fractionation processes during solar wind formation. The solar wind provides information on the isotopic composition for most volatile elements for the solar atmosphere, the bulk Sun and hence, on the solar nebula from which it formed 4.6 Ga ago. Our data reveal a heavy isotope depletion in the slow solar wind compared to the fast wind composition by 63.1 {+-} 2.1 per mille for He, 4.2 {+-} 0.5 per mille amu{sup -1} for Ne and 2.6 {+-} 0.5 per mille amu{sup -1} for Ar. The three Ne isotopes suggest that isotopic fractionation processes between fast and slow solar wind are mass dependent. The He/H ratios of the collected slow and fast solar wind samples are 0.0344 and 0.0406, respectively. The inefficient Coulomb drag model reproduces the measured isotopic fractionation between fast and slow wind. Therefore, we apply this model to infer the photospheric isotopic composition of He, Ne, and Ar from our solar wind data. We also compare the isotopic composition of oxygen and nitrogen measured in the solar wind with values of early solar system condensates, probably representing solar nebula composition. We interpret the differences between these samples as being due to isotopic fractionation during solar wind formation. For both elements, the magnitude and sign of the observed differences are in good agreement with the values predicted by the inefficient Coulomb drag model.

  15. A formational model for the polygonal terrains of Mars: Taking a crack at the genesis of the Martian polygons

    Science.gov (United States)

    Wenrich, M. L.; Christensen, P. R.

    1993-01-01

    The mechanism for the genesis of the polygonal terrains in Acidalia and Utopia Planitia has long been sought: however, no completely satisfying model was put forth that characterizes the evolution of these complexly patterned terrains. The polygons are roughly hexagonal but some are not entirely enclosed by fractures. These polygonal features range in widths from approximately 5 to 20 km. Several origins were proposed that describe the polygon borders as desiccation cracks, columnar jointing in a cooled lava, or frost-wedge features. These tension-induced cracking hypotheses were addressed by Pechmann, who convincingly disputes these mechanisms of formation based on scale magnitude difficulties and morphology. Pechmann suggests instead that the cracks delineating the 5-20-km-wide polygons on the northern plains of Mars are graben resulting from deep-seated, uniform, horizontal tension. The difficulty with this hypothesis is that no analogous polygonal forms are known to have originated by tectonism on Earth. McGill and Hills propose that the polygonal terrains on Mars resulted from either rapid desiccation of sediments or cooling of volcanics coupled with differential compaction of the material over a buried irregular topographic surface. They suggest that fracturing was enhanced over the areas of positive relief and was suppressed above the topographic lows. McGill and Hills suggest that the spacing of the topographic highs primarily controls the size of the Martian polygons and the physics of the shrinkage process is a secondary concern. Ray et. al. conducted a terrestrial study of patterned ground in periglacial areas of the U.S. to determine the process responsible for polygonal ground formation. They developed a model for polygon formation in which convection of seasonal melt water above a permafrost layer, driven by an unstable density stratification, differentially melts the permafrost interface, causing it to become undulatory.

  16. Adam. Příběh prvního člověka v knize Genesis a v Koránu

    Directory of Open Access Journals (Sweden)

    Mlada Mikulicová

    2014-10-01

    Full Text Available In both books Adam is presented as a prototypical man created from physical elements and endowed with divine inspiration that makes him capable of rational actions. While Genesis narrates the story of Adam from his creation to his death, stressing chronology and future development in history, the Qur’an’s rendering is fragmentary. Of vast underlying popular traditions on Adam and Eve, Genesis previews the history of God’s covenant and salvific action towards humankind while the Qur’an persists on the theme of human disobedience and God’s absolute governance. Despite common themes as the createdness of man, his superiority over the rest of the creation, the complementary nature of human being as man and woman, the loss of happiness through disobedience to God’s law, the two stories differ in interpretation. While the acceptance of evil into human heart is reflected as voluntary in Genesis, the Qur’an finds excuse in the revolt of Satan who is shown in a more active role than man. Eliminating the notions of man as the image of God, and the final abolishment of evil, the Qur’an uses Adam’s story to demonstrate the principal axioms of Islamic doctrine: God must be obeyed and Satan’s lures avoided else man will not attain the Garden; Adam is a prototypal prophet, informing of these truths. Adam and Eve, according to the narration of the Book of Genesis, represent human existence in the drama of knowing evil and distress, hiding from God, and hearing his promise of future salvation that begins to unroll in their progeny. V biblicke knize Genesis i v Koranu je Adam představen jako prototyp člověka stvořeneho z fyzickych prvků a „Božiho vdechnuti“ racionality. Biblicke vypravěni je chronologicky přiběh, Koran zmiňuje pouze některe časti sparsatim v deseti různych surach. Genesis jakožto prolog k biblickemu celku vybira tradični latky k dokumentaci Božich dějin spasy, zatimco Koran eliminuje všechno, co nesouvisi

  17. Discrimination and quantification of contamination and implanted solar wind in Genesis collector shards using grazing incidence synchrotron x-ray techniques: Initial results

    International Nuclear Information System (INIS)

    Kitts, K.; Sutton, S.; Eng, P.; Ghose, S.; Burnett, D.

    2006-01-01

    Grazing incidence X-ray fluorescence is a non-destructive technique that can differentiate the embedded solar wind component from surface contamination and collector background in the Genesis shards. Initial solar Fe abundance in D30554 is 8 x 10 12 /cm 2 . Accurate knowledge of the composition of the Sun provides a baseline, which allows an understanding of how the solar system has evolved over time and how solar processes and solar wind mechanics behave. Unfortunately, the errors in photospheric abundances are too large for many planetary science problems and this hampers our understanding of these different processes. Analyses of solar wind implanted in meteorites or lunar soils have provided more precise data but alteration processes on these bodies may complicate such information. In response to this need for pristine solar wind samples, NASA developed and launched the Genesis Probe. Unfortunately, the probe smashed into the Utah desert shattering the 300 collector plates into 15,000+ pieces all of which are now coated in a both a fine terrestrial dust and Si and Ge powder from the disrupted collectors themselves. The solar wind penetration depth is 100-200 nm and the superposed contamination layers are typically 40-50 nm. Stringent cleaning regimes have the potential of removing the solar wind itself. The best solution is to have sufficient spatial resolution to separately analyze the surface contamination and penetrated solar wind. To that end, three Genesis collector array shards and their appropriate flight spares were characterized via grazing incidence x-ray fluorescence and x-ray reflectivity. The goals were (1) to evaluate the various cleaning methods used to eliminate contamination, (2) to identify the collector substrates most suited for this technique, (3) to determine whether the solar wind signature could be deconvolved from the collector background signature, and (4) to measure the relative abundances of Ca to Ge in the embedded solar wind.

  18. Preliminary discussion on possible genesis of crustal rotation, its impact on geotectonic evolution and its relation to large-scale metallogeny in Hunan province and adjacent regions

    International Nuclear Information System (INIS)

    Shu Xiaojing

    2005-01-01

    Hunan province and adjacent regions show ring-form distribution features both on surface geologic structure and geophysical field. Such features might result from the rotation movement of the earth crust and exert serious impact on the geotectonic evolution and large-scale metallogeny in Hunan province and adjacent regions. This paper makes a preliminary discussion on the possible genesis of such rotation movement, as well as the associated series of geologic processes and its relation to large-scale metallogeny in Hunan province and adjacent regions. (authors)

  19. Glucose-regulated protein 78 regulates the expression of mitochondrial genesis proteins in HBV-related hepatocellular carcinoma: a clinical analysis

    Directory of Open Access Journals (Sweden)

    LI Yaping

    2017-10-01

    Full Text Available ObjectiveTo investigate the expression of glucose-regulated protein 78 (GRP78 in HBV-related hepatocellular carcinoma (HBV-HCC and its association with clinicopathological features, as well as its regulatory effect on mitochondrial genesis proteins in hepatoma cells, and to provide a basis for new strategies for the prevention and treatment of HCC. MethodsTissue samples were collected from 54 patients with HBV-HCC, and immunohistochemistry and Western blot were used to measure the expression of GRP78, Lon, TFAM, and cytochrome C oxidase Ⅳ (COXⅣ. The expression of GRP78 in hepatoma cells was interfered by siRNA, and then the expression of GRP78, Lon, mitochondrial transcription factor A (TFAM, and COX Ⅳ was measured. Quantitative real-time PCR was used to measure the level of mitochondrial DNA (mtDNA in clinical specimens and HCC cells after GRP78 expression was interfered with. A statistical analysis was performed for clinical and experimental data. The t-test was used for comparison of continuous data between groups, the Fisher′s exact test was used for comparison of categorical data between groups, and the Kaplan-Meier method was used for survival analysis. Results Compared with the adjacent tissues, HBV-HCC tissues had significantly higher expression of GRP78 and Lon (t=9.135 and 5523, both P<0.0001 and significantly lower expression of the mitochondrial genesis proteins TFAM and COX Ⅳ and mtDNA level (t=2.765, 4260, and 12.280, P=0.011, <0.001, and <0.001. There were significant increases in the expression of the mitochondrial genesis proteins TFAM and COX Ⅳ and mtDNA level after the interference with GRP78 expression in hepatoma cells (all P<0.05. There were significant differences in the expression of GRP78 between patients with different numbers of tumors, patients with and without portal vein tumor thrombus, and patients with different tumor stages (P=0.016, 0.003, and 0.045. The patients with low GRP78

  20. 浙江省观赏石成因和分布规律%Distribution, Genesis and Regional Geological Background of View Stones in Zhejiang Province

    Institute of Scientific and Technical Information of China (English)

    陈美君; 王杜涛; 王加恩

    2012-01-01

    By the research and evaluation on the view stones in Zhejiang, it proves that there are plenty of various resources of view stones; 30 types and 63 localities of view stones have been found. Now the paper describes the main several stones' distribution and genesis in detail, especially researches from the regional geological background.%浙江省内观赏石资源丰富、类型齐全,目前已查明观赏石产地63处。本文初步探讨了浙江观赏石成因和分布规律。

  1. Genesis and classification of soils developed on gabbro in the high reliefs of Maroua region, North Cameroon

    Directory of Open Access Journals (Sweden)

    Désiré Tsozué

    2017-04-01

    Full Text Available The purpose of this work was to examine the genesis, properties and classification of soils resulting from the weathering of gabbro rock in the high reliefs of Maroua in the Far North Region of Cameroon. The studied soils were ~ 2 m thick, made of four horizons which consisted of coarse saprolite, fine saprolite, loose loamy clayey horizon and humiferous horizon. From petrographical view point, at the bottom of the soil profile, the preservation of the bedrock structure was marked by numerous remnants of altered plagioclases shapes. The groundmass was characterized by a double spaced fine, ranging to equal, enaulic c/f related distribution pattern. It was yellowish, characterized by weakly separated granular microstructure in the fine saprolite and had a speckled and cloudy limpidity in the loose loamy clayey horizon. Secondary minerals consisted of montmorilonite, kaolinite, goethite, quartz, gibbsite, lepidocrocite, sepiolite, feldspar and calcite. Globally, Si/Al ratio ranged between 2.85 and 3.24. The chemical index of alteration ranged from 50.95 to 55.27 % while the mineralogical index of alteration values were between 1.90 and 10.54 %. Physicochemically, soil pH varied from slightly acidic to slightly above neutral. Soil organic carbon contents were low to very low. Exchangeable bases contents were high, mostly represented by Ca2+ and Mg2+. The CEC of soils and the CEC of clay were also high, ranging respectively between 53.68 and 82.88 cmol(+.kg-1, and 116.80 and 181.38 cmol(+.kg-1. The studied soils were classified as dystric haplustepts clayey isohyperthermic. They were developed in situ by the collapse of primary mineral structures from the bottom of the coarse saprolite, due to leaching as a result of bisiallitisation and monosiallitisation. This is accompanied by a progressive ferruginization of materials, confirmed by the densification under the microscope of goethitic brown veil from the base to the loamy clay horizon and the

  2. Subduction-like fluids in the genesis of Mt. Etna magmas: evidence from boron isotopes and fluid mobile elements

    Science.gov (United States)

    Tonarini, Sonia; Armienti, Pietro; D'Orazio, Massimo; Innocenti, Fabrizio

    2001-11-01

    New whole-rock B, Sr, Nd isotope ratios and 87Sr/ 86Sr on clinopyroxenes have been collected to study the enrichment of fluid mobile elements (FMEs) observed in Mt. Etna volcanics. Etna volcano, one of the most active in the world, is located in an extremely complex tectonic context at the boundary between colliding African and European plates. The analytical work focuses on current (1974-1998) and historic (1851-1971) eruptive activity, including some key prehistoric lavas, in order to interpret the secular shift of its geochemical signature to more alkaline compositions. Boron is used as a tool to unravel the role of fluids in the genesis of magmas, revealing far-reaching consequences, beyond the case study of Mt. Etna. Small variations are observed in δ 11B (-3.5 to -8.0‰), 87Sr/ 86Sr (0.70323-0.70370), and 143Nd/ 144Nd (0.51293-0.51287). Moreover, temporal evolution to higher δ 11B and 87Sr/ 86Sr, and to lower 143Nd/ 144Nd, is observed in the current activity, defining a regular trend. Sr isotopic equilibrium between whole-rock and clinopyroxene pairs indicates the successive introduction of three distinct magma types into the Etna plumbing system over time; these are characterized by differing degrees of FME enrichment. In addition, certain lavas exhibit evidence for country rock assimilation, magma-fluid interaction, or magma mixing in the shallow feeding system; at times these processes apparently lowered magmatic δ 11B and/or induced Sr isotopic disequilibrium between whole rock and clinopyroxene. The regular increase of δ 11B values is correlated with Nb/FME and 87Sr/ 86Sr ratios; these correlations are consistent with simple mixing between the mantle source and aqueous fluids derived from nearby Ionian slab. The best fit of Mt. Etna data is obtained using an enriched-MORB mantle source and a fluid phase with δ 11B of about -2‰ and 87Sr/ 86Sr of 0.708. We argue that the slab window generated by differential roll-back of subducting Ionian

  3. Geochemical constraints on genesis of Paleoproterozoic A-type granite in the south margin of North China Craton

    Science.gov (United States)

    Xue, Shuo; Xu, Yang; Ling, Ming-Xing; Kang, Qing-Qing; Jiang, Xiao-Yan; Sun, Sai-Jun; Wu, Kai; Zhang, Zhe-Kun; Luo, Ze-Bin; Liu, Yu-Long; Sun, Weidong

    2018-04-01

    Paleoproterozoic A-type granites are widely outcropped in the North China Craton (NCC), particularly in the Trans-North China Orogen. However, their genesis and tectonic significance remain obscure. Here we report systematic studies on geochronology and geochemical characteristics of A-type granite in Huayangchuan, south margin of the NCC. The samples are enriched in total alkali (K2O + Na2O > 8.97 wt%), and depleted in MgO (0.84-0.93 wt%), CaO (1.28-1.90 wt%) and P2O5 (0.18-0.20 wt%), with high FeOT/MgO (5.69-6.67). They are characterized by high Zr + Y + Nb + Ce values (1293-1392 ppm) and 10,000 × Ga/Al ratios (3.14-3.35), which are typical characteristics of A-type granite. The Huayangchuan A-type granite can be further classified as A1-type subgroup based on particular geochemical features, e.g., low Y/Nb (0.87-1.00) and Yb/Ta (0.88-1.10). High precision zircon U-Pb dating of the A-type granite by secondary ion mass spectrometry (SIMS) yields Paleoproterozoic 207Pb/206Pb ages of 1829.5 ± 2.5 Ma. The low zircon ɛHf(t) values (-6.97 to -10.45), along with zircon Hf model age of 2.7-2.9 Ga, indicate that the Huayangchuan A-type granite was derived from partial melting of the ancient continental crust with contribution of enriched mantle components. The low zircon δ18O composition (4.00 to 6.78‰) indicates that the zircons were crystallized from low δ18O magmas, which derived from the crust metasomatized by low δ18O mantle fluids or melts. The E-W trend A1-type granitic plutons in the NCC are generally outcropped in a rift tectonic regime, which is consistent with the development of the mantle plume in the Xiong'er district. The large volume of basaltic magmas, generated by mantle plume head, underplated the lower continental crust and formed the Huayangchuan A-type granite.

  4. Genesis of iron-apatite ores in Posht-e-Badam Block (Central Iran) using REE geochemistry

    Science.gov (United States)

    Mokhtari, Mir Ali Asghar; Zadeh, Ghader Hossein; Emami, Mohamad Hashem

    2013-06-01

    Rare earth elements in apatites of different ore types show characteristic patterns which are related to different modes of formation of the ores. Most of the apatite-bearing iron ores are associated with alkaline magmas with LREE/HREE fractionation varying from moderate to steep. Iron-apatite deposits in Posht-e-Badam Block (Central Iran) have a high concentration of REE (more than 1000 ppm up to 2.5%), and show a strong LREE/HREE ratio with a pronounced negative Eu anomaly. This REE pattern is typical of magmatic apatite and quiet distinct from sedimentary apatites (phosphorites) which have a low REE contents and Ce negative anomalies. On the other hand, they are comparable to the REE patterns of apatites in Kiruna-type iron ores in different parts of the world. The REE patterns of apatites, iron-apatite ores and iron ores are similar and only have different REE contents. This similarity indicates a genetic relation for these rocks. Most of the iron-apatite deposits in Central Iran have similar REE patterns too, which in turn show a genetic relation for all of these deposits. This similarity indicates a similar origin and processes in their genesis. There are some small intrusions around some of the iron-apatite deposits that are petrographically identified as syenite and gabbro. These intrusions also have REE patterns similar to that of iron-apatite ores. This demonstrates a genetic relation between these intrusions and iron-apatite ores. The REE patterns of apatites in different deposits of Posht-e-Badam Block iron-apatite ores show an affinity to alkaline to sub-alkaline magmas and rifting environment. The alkaline host rocks of Central Iran iron-apatite ores are clearly related to an extensional setting where rifting was important (SSE-NNW fault lines). A probable source for this large scale ore forming processes is relatively low partial melting of mantle rocks. The ores have originated by magmatic differentiation as a late phase in the volcanic cycle

  5. Genesis and formation attribute of military authorities of the Ukrainian сossacks in the XVI – XVIII centuries

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    Nadiya V. Babkova

    2016-02-01

    Full Text Available Here are considered the historical roots of formation and genesis of bunchuks as a part of the whole kleinod complex of Kosh Otamans and Hetmans of the Ukrainian Cossacks. Turkic lexeme «bunchuk» over time has transformed into modern term that is common in Ukrainian culture. Traditionally, the first recorded case of bunchuks’ use by military is associated with the name of the Arab Caliph Abu Bakr and his military battles on the territory of Syria in the 7th century. During the active cross-cultural contacts in the early 13th century, firstly bunchuks became known among the Mongols and later among the Turks. Early Ottomans used them not only as a military sign, but also as a ranking marker of the court official, status present, which raised the social status of a person. From Turks bunchuks were taken by the representatives of the Commonwealth of Poland and at the beginning gave them a meaning of the important symbol of Quarter Army Hetman military power and later, from the middle of the XVII century, of the Polish king. Historical tradition linked the use of bunchuks by Ukrainian Cossacks with the military reforms of Polish monarch Stefan Batory. But modern scientists, studying military history of the Cossacks in the first quarter of the XVII century and using the materials of Polish archives denied this statement and stressed the attention of the Turkish-Tatar vector. For Zaporozhian Cossacks bunchuks were among the attributes of legitimacy or legality of certain actions. In the external design dominated red and black color schemes. National Symbols of early modern Ukrainian state in the middle of the 17th – 18th c., which basis was formed of the attributes of power Zaporozhian Cossacks, recorded bunchuks as personal banners of Hetmans. In order to make the distinction from Zaporozhian Cossacks, Hetmans started using white bunchuks. Historical records kept information about these signs is in the arsenal of Hetman Bohdan Khmelnytsky, Petro

  6. Nanoscale Study of Clausthalite-Bearing Symplectites in Cu-Au-(U Ores: Implications for Ore Genesis

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    Nicholas D. Owen

    2018-02-01

    Full Text Available Symplectites comprising clausthalite (PbSe and host Cu-(Fe-sulphides (chalcocite, bornite, and chalcopyrite are instructive for constraining the genesis of Cu-Au-(U ores if adequately addressed at the nanoscale. The present study is carried out on samples representative of all three Cu-(Fe-sulphides displaying clausthalite inclusions that vary in size, from a few µm down to the nm-scale (<5 nm, as well as in morphology and inclusion density. A Transmission Electron Microscopy (TEM study was undertaken on foils prepared by Focussed Ion Beam and included atom-scale High-Angle Annular Dark-Field Scanning TEM (HAADF-STEM imaging. Emphasis is placed on phase relationships and their changes in speciation during cooling, as well as on boundaries between inclusions and host sulphide. Three species from the chalcocite group (Cu2–xS are identified as 6a digenite superstructure, monoclinic chalcocite, and djurleite. Bornite is represented by superstructures, of which 2a and 4a are discussed here, placing constraints for ore formation at T > 265 °C. A minimum temperature of 165 °C is considered for clausthalite-bearing symplectites from the relationships with antiphase boundaries in 6a digenite. The results show that alongside rods, blebs, and needle-like grains of clausthalite within the chalcocite that likely formed via exsolution, a second, overprinting set of replacement textures, extending down to the nanoscale, occurs and affects the primary symplectites. In addition, other reactions between pre-existing Se, present in solid solution within the Cu-(Fe-sulphides, and Pb, transported within a fluid phase, account for the formation of composite, commonly pore-attached PbSe and Bi-bearing nanoparticles within the chalcopyrite. The inferred reorganisation of PbSe nanoparticles into larger tetragonal superlattices represents a link between the solid solution and the symplectite formation and represents the first such example in natural materials

  7. The Genesis of Capitalism

    DEFF Research Database (Denmark)

    Li, Xing

    2004-01-01

     This paper aims to offer a framework of interpreting the “evolution” of capitalism that is reaching every corner of the world and has achieved greater legitimacy than at any time in human history. It covers an interdisciplinary discussion on the development of market capitalism that has been...... characterized by a dual process: unanticipated origin (cultural and historical) and anticipated progress (political economy). The point of departure of this paper is that although the advancement of market capitalism is a process of societal development involving historical, cultural and religious causes...... (historical, divine, spiritual, miraculous), the establishment of capitalism is less the result of a force for cultural and economic dynamism than the realization of a political project. In other words, from being an enterprise within defined geographical boundaries to becoming a global project is first...

  8. Genesis of social entrepreneurship

    DEFF Research Database (Denmark)

    Kulothungan, Gladius

    of institutions and internal, in terms of motivations and drive in a combination propel the social entrepreneur or the group to create social enterprises. The aim of the investigation is to explore and explain how and why certain individuals/groups create/generate innovative responses/ solutions - understood...... – grants, donations and revenue streams generated by business activities and 4/ they seldom act alone but work within an organizational context. GK has done a number of English and Danish empirical case studies of different social enterprises and beginning the analyses of these....

  9. The genesis of ores

    International Nuclear Information System (INIS)

    Brimhall, G.

    1991-01-01

    Human history and technology have been shaped by metals. How did they become concentrated in minable deposits located so conveniently near the earth's surface? The author explains the mechanisms of fluid transport-by magma, water and even air and wind-responsible for the chemical and physical interactions that created bodies of metallic ores throughout geologic history. From their formation to their modification at the surface of the earth, ore deposits are geologically transitory and reflect dynamic processes within the earth as well as atmospheric and climatic influences on hydrologic systems. As highly reactive supracrustal systems, they then serve as geochemical sensors providing a powerful record and set of tracer elements for deducing the history, transport paths and forces operative in the crust

  10. Petrography, Geochemistry and Proposed Genesis of Ordovician Oolitic Iron Formation Members of the Lashkarak Formation, Eastern Alborz

    Directory of Open Access Journals (Sweden)

    Mansoore Maghsoudloo Mahalli

    2016-07-01

    Full Text Available Introduction Oolitic iron formations are sedimentary rocks with >5 vol.% oolites and >15 wt.% iron, corresponding to 21.4 wt.% Fe2O3 (Young, 1989; Petranek and Van Houten, 1997; Mucke and Farshad, 2005. In Iran, new iron oolite-bearing members have been identified in the Lashkarak Formation (lower-middle Ordovician in the Abarsej, Dehmola and Simehkuh sections, eastern Alborz (Ghobadi Pour et al., 2011. At present, the mineralogy and geochemistry of these members are not known. Consequently, research reported here was conducted to reveal the mineralogical and geochemical characteristics of Ordovician oolitic iron formationmembers and to discuss their genesis and economic importance. Materials and Analyses Field geology and sampling was carried out to collect 25 samples from the ooliticiron formation members in the Abarsej, Dehmola and Simehkuh section in eastern Alborz. Samples were prepared for polished-thin sections (n=10, XRD analysis (n=15. Whole-rock chemical analysis (n=15 by XRF for major elements and by ICP-ES for trace elements was performed by laboratories at the SarCheshmeh copper mine complex, Kerman, Iran. One sample was analyzed by SEM at the Wales Museum, UK. Results Microscopic studies show that the oolitic iron formation members are hosted by carbonate argillite rocks. They are mainly composed of oolites rather than pisoliths (small bodies somewhat larger and more irregular than oolites, whereas oolites have mainly ellipsoidal forms and locally spherical shapes. Most (6 oolites show banding with a central core. Simple oolites without a core are scarce. Mineralogically, oolites are mainly chamositic and hematitic in composition; goethite, pyrite and glauconite occur in traces and siderite is absent. Quartz, calcite and zircon are accessory minerals which are present in the groundmass. Geochemically, TFeO % of the oolitic iron formation horizons ranges from 8 to 48 % with an average of 21%. The CaO content ranges from 2 to 37% and

  11. Importance of No. 21 chromosome in translocation t(8:21) in acute myelocytic leukemia (AML) to the genesis of the disease

    Energy Technology Data Exchange (ETDEWEB)

    Ishihara, T; Minamihisamatsu, M

    1986-05-01

    The results are reported of the chromosome analysis of 17 cases of acute myelocytic leukemia (AML), mostly belonging to M2 of the FAB classification, especially on the translocation t(8:21) and its variant translocations. The presence of two cases with simple variant translocation not involving No. 8 chromosome seems to suggest that No. 21 chromosome is more important to the genesis of AML than the No. 8 chromosome. This assumption appears to be supported by findings on cases with complex translocation: In two cases with complex translocation, the portion translocated from No. 21 chromosome onto No. 8 was firmly maintained in the specific site (q21) on No. 8 whereas the portion translocated from No. 8 chromosome onto No. 21 was involved in further translocation with another chromosome, onto which it was re-translocated. The results of the present cytogenetic study indicate that the analysis of variant translocations in various specific chromosome translocations in leukemia and other malignant disorders is very useful to elucidate the problem as to whether the genesis of such disorders lies in either one or both of the pair of chromosomes involved in the specific translocations of the respective diseases.

  12. The genesis of the ore hosting 'dolomitic marble' in the Bayan Obo deposit, Inner Mongolia, China: constrained by isotopic results

    International Nuclear Information System (INIS)

    Ding Tiping; Tian Shihong; Wang Defang; Jiang Shaoyong; Bai Ruimei

    2003-01-01

    The Bayan Obo Fe-REE-Nb ore deposit, Inner Mongolia, China is a super large REE deposit. This deposit attracts attentions of many geologists and geochemists for its unique geological characters and geotectonic background. However, there are quite a number of controversies on various aspects of its genesis, such as when the ore deposit was formed, where the ore forming materials came from and what conditions and geotectonic environment the deposit was formed. Among them, the genesis of ore bearing 'dolomitic marble' is a focus point of debating. isotopic methods are important tools for study on ore deposits. Therefore, supplemental stable isotope investigation was undertaken in this study to reach more information on the forming conditions of 'dolomitic marble'. The high contents of REE and Nb, the REE distribution pattern, the low initial 87 Sr/ 86 Sr ratio and low δ 30 Si values of trace silica in 'dolomitic marble' all indicate its magmatic origin. The high δ 18 O values of carbonate and silicate minerals, and the relatively high δ 34 S values indicate that this rock had experienced isotopic exchange with sea water, implying their submarine volcanic origin. The δ 13 C values observed in carbonate and silicate minerals can also be explained by carbonatite assimilated by oceanic carbonate. Therefore, based on its isotopic characters, the 'dolomitic marble' is more likely of volcanic carbonatite rock formed during middle Proterozoic era. (authors)

  13. COMPOSITION, CHARACTERISTICS OF THE ENVIRONMENT, CHOROLOGY AND GENESIS OF SNOUT BEETLES OF PTOCHUS SCHOENH GENUS AND CREATION OF MAPS OF THEIR AREAS IN THE REPUBLIC OF DAGHESTAN

    Directory of Open Access Journals (Sweden)

    Asiyat M. Mukhtarova

    2017-01-01

    Full Text Available Abstract. Aim. The aim of the work was to study the characteristics of the ecology, the chorology and genesis of thesnout beetles of Ptochus genus in Dagestan, as well as designing the maps of their ranges. Materials and methods. The work was based on the materials of expedition and ecology-faunistic studies conducted from 1999 to 2017 in various regions of Dagestan using the basic entomological methods. For mapping were used the following source materials: the database created by the authors for the study group, the map of the Republic of Dagestan taken fromthe National Atlas of Russia, topographic maps from MapInfo 15.2 and maps made in Adobe Illustrator CreativeCloud. Results. The characteristics of the ecology and geographic distribution of the snout beetles of Ptochus genus in Dagestan have been studied; the following maps are created: "The areas of the snout beetles of Ptochus genus of Dagestan" and "The areas of the snout beetles of Ptochus genus of the Botlikh trench of Dagestan". Conclusion. In the fauna of Dagestan, 7 species of Ptochus snout beetles, associated with arid steppe and semidesert landscapes,ed distribution maps and bioecological features, a hypothesis was put forward on the genesis of the study group in the territory of Dagestan.

  14. Experimental approbation of a new ultrosound contrast agent based on sulfur geksafluoride in diagnostics of focal liver lesions of inflammatory genesis

    Directory of Open Access Journals (Sweden)

    S. V. Fomina

    2017-01-01

    Full Text Available Purpose of the study. Experimental approbation of a new domestic ultrasound contrast agent (UCA based on sulfur hexafluoride in the diagnosis of focal liver lesions of inflammatory genesis.Materials and methods. The investigated ultrasound contrast agent (UCA was a heterogeneous gas-liquid system consisting of micro bubbles of a sparingly soluble gas of sulfur hexafluoride (SF6 surrounded by a flexible mobile membrane of surfactants. Experimental work was carried out on rabbits. The study group included rabbits of males and females with focal liver lesion of inflammatory genesis (n = 12 weighing 1500- 1700 g. UCA was administered to animals in the ear vein. Focal lesions of the liver in animals were created in the experimental laboratory conditions. 14 days after the operation, all animals were subjected to ultrasound examination of the surgical intervention zones by using the Toshiba Aplio 400 scanners (Japan with a 3,5–8 MHz convection sensor. In a natural study, the size, structure and echogenicity of the focus were assessed, the degree of vascularization, the evenness and clarity of the contours were determined. When performing post contrast ultrasound, the time of the onset of contrast enhancement, the total duration of contrast, the changes in the contrast enhancement of the focus in different phases of the study were measured, the dimensions of the focus were measured, and the evenness and acuity of contours were measured. For histological examination, liver fragments and lungs were used. 

  15. Prolonged oxidative stress down-regulates Early B cell factor 1 with inhibition of its tumor suppressive function against cholangiocarcinoma genesis

    Directory of Open Access Journals (Sweden)

    Napat Armartmuntree

    2018-04-01

    Full Text Available Early B cell factor 1 (EBF1 is a transcription factor involved in the differentiation of several stem cell lineages and it is a negative regulator of estrogen receptors. EBF1 is down-regulated in many tumors, and is believed to play suppressive roles in cancer promotion and progression. However, the functional roles of EBF1 in carcinogenesis are unclear. Liver fluke-infection-associated cholangiocarcinoma (CCA is an oxidative stress-driven cancer of bile duct epithelium. In this study, we investigated EBF1 expression in tissues from CCA patients, CCA cell lines (KKU-213, KKU-214 and KKU-156, cholangiocyte (MMNK1 and its oxidative stress-resistant (ox-MMNK1-L cell lines. The formation of 8-oxo-7,8-dihydro-2′-deoxyguanosine (8-oxodG was used as an oxidative stress marker. Our results revealed that EBF1 expression was suppressed in cancer cells compared with the individual normal bile duct cells at tumor adjacent areas of CCA tissues. CCA patients with low EBF1 expression and high formation of 8-oxodG were shown to correlate with poor survival. Moreover, EBF1 was suppressed in the oxidative stress-resistant cell line and all of CCA cell lines compared to the cholangiocyte cell line. This suggests that prolonged oxidative stress suppressed EBF1 expression and the reduced EBF1 level may facilitate CCA genesis. To elucidate the significance of EBF1 suppression in CCA genesis, EBF1 expression of the MMNK1 cell line was down-regulated by siRNA technique, and its effects on stem cell properties (CD133 and Oct3/4 expressions, tumorigenic properties (cell proliferation, wound healing and cell migration, estrogen responsive gene (TFF1, estrogen-stimulated wound healing, and cell migration were examined. The results showed that CD133, Oct3/4 and TFF1 expression levels, wound healing, and cell migration of EBF1 knockdown-MMNK1 cells were significantly increased. Also, cell migration of EBF1-knockdown cells was significantly enhanced after 17

  16. Discrimination and quantification of implanted solar wind in Genesis collector shards using grazing incidence synchrotron x-ray techniques: New detector initial results

    International Nuclear Information System (INIS)

    Kitts, K.; Choi, Y.; Sutton, S.R.; Ghose, S.; Burnett, D.; Eng, P.

    2008-01-01

    Accurate knowledge of the composition of the Sun provides a baseline, which allows an understanding of how the solar system has evolved over time and how solar processes and solar wind mechanics behave. Unfortunately, the errors in photospheric abundances are too large for many planetary science problems and this hampers our understanding of these different processes. Analyses of solar wind implanted in meteorites or lunar soils have provided more precise data [e.g. 1 and references therein] but the extent to which alteration processes on these bodies complicate such information is only now being determined. Therefore, in order to obtain pristine solar wind samples, NASA developed and launched the Genesis Discovery Mission. Unfortunately, the probe crash-landed shattering the 300 collector plates into 15,000+ pieces complicating the analysis and necessitating the development of new analytical techniques and equipment. Thus, shards from the Genesis collector array and their appropriate flight spares are currently being characterized via grazing-incidence synchrotron x-ray techniques at the Advanced Photon Source at Argonne National Laboratory. The goals are (1) determine solar wind fluences of the elements Ca-Ge by grazing-incidence angle-resolved x-ray fluorescence (XRF) and x-ray reflectivity, (2) improve data reduction via the development of XRF spectral deconvolution routines and develop modeling algorithms for reflectivity and fluorescence yield analysis in order to determine element specific depth profiles from which absolute concentration may be extracted and (3) designing and developing a new multi-element silicon multi-channel (SMCD) detector system. These improvements will increase our sensitivity by a factor of three or more, reduce measurement time at a given sensitivity to one-eighth and the minimum detection limit would be reduced by a factor of 3 to ∼3 x 10 8 atoms/cm 2 .

  17. Delayed onset of changes in soma action potential genesis in nociceptive A-beta DRG neurons in vivo in a rat model of osteoarthritis

    Directory of Open Access Journals (Sweden)

    Henry James L

    2009-09-01

    Full Text Available Abstract Background Clinical data on osteoarthritis (OA suggest widespread changes in sensory function that vary during the progression of OA. In previous studies on a surgically-induced animal model of OA we have observed that changes in structure and gene expression follow a variable trajectory over the initial days and weeks. To investigate mechanisms underlying changes in sensory function in this model, the present electrophysiological study compared properties of primary sensory nociceptive neurons at one and two months after model induction with properties in naïve control animals. Pilot data indicated no difference in C- or Aδ-fiber associated neurons and therefore the focus is on Aβ-fiber nociceptive neurons. Results At one month after unilateral derangement of the knee by cutting the anterior cruciate ligament and removing the medial meniscus, the only changes observed in Aβ-fiber dorsal root ganglion (DRG neurons were in nociceptor-like unresponsive neurons bearing a hump on the repolarization phase; these changes consisted of longer half width, reflecting slowed dynamics of AP genesis, a depolarized Vm and an increased AP amplitude. At two months, changes observed were in Aβ-fiber high threshold mechanoreceptors, which exhibited shorter AP duration at base and half width, shorter rise time and fall time, and faster maximum rising rate/maximum falling rate, reflecting accelerated dynamics of AP genesis. Conclusion These data indicate that Aβ nociceptive neurons undergo significant changes that vary in time and occur later than changes in structure and in nociceptive scores in this surgically induced OA model. Thus, if changes in Aβ-fiber nociceptive neurons in this model reflect a role in OA pain, they may relate to mechanisms underlying pain associated with advanced OA.

  18. Study of genesis in Qahr-Abad fluorite deposit using fluid inclusion, southeast of Saqqez, the Kurdistan province

    Directory of Open Access Journals (Sweden)

    Mehrdad Barati

    2017-07-01

    . Discussion Thermometric investigations indicate that homogenization temperatures for primary and pseudo secondary fluid inclusions in all fluorite types range from 155 to 245°C with an average of 187°C. Gas phase changes to liquid phase in the homogenization processes. The degree of fillings in most inclusions are more than 90%. -23 to -18 °C with an average of -20.7°C. There are eutectic temperatures in the freezing method and calculated salinity is 30.8 wt% NaCl equivalents in terms of the H2O-CO2-NaCl system. The Bernoulli Effect has occurred in this resource (Barnes, 1998. Isothermal mixing, boiling, surface fluid dilution and depressurization are four processes that have effects on the mineralization in this resource (Wilkinson, 2001. Finally we think, Qahr -abad fluorite deposit has been prepared by hydrothermal to epithermal processes and fluids have basin origin (fossil waters (Tajoddyn, et al, 2010 and the orebody has precipitated from this fluid, when it was mixed with cold surface waters. References Barnes, H.L., 1998. Geochemistry of hydrothermal ore deposits. John Wiley & Sons, Malaysia, 972 pp. Kholghi Khasraghi, M.H., 1999. Geological map of Irankhah. Scale 1:100,000. Geological Survey of Iran. Moslehi, M., 2013. The study of fluid inclusion and geochemistry of Qahr-Abad Soliman deposit in Kurdistan province. M.Sc. Thesis, Bu-Ali Sina University, Hamedan, Iran, 142 pp. (in Persian with English abstract Tajoddyn, H., Rastad, A., Yaghobpour, A. and Mohajel, M., 2010. The genesis of Barica Gold massive sulfide deposit, east of Sardasht, NW of metamorphic Sanandaj –Sirjan zone base on structure, texture and micro thermometric studies. Journal of Economic Geology, 2(1: 97-118. (in Persian Talaii, B., 2010. The study of mineralogy and geochemistry of Qahr-Abad fluorite deposit, SE of Sagez city, Kurdistan province. M.Sc. Thesis, University of Uromieh, Uromieh, Iran, 119 pp. (in Persian with English abstract Wilkinson, J.J., 2001. Fluid inclusions in

  19. Climatology of summer midtropospheric perturbations in the US northern plains. Part II: large-scale effects of the Rocky Mountains on genesis

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Shih-Yu. [Iowa State University, Department of Geological and Atmospheric Sciences, Ames, IA (United States); Utah State University, Utah Climate Center, Logan, UT (United States); Chen, Tsing-Chang [Iowa State University, Department of Geological and Atmospheric Sciences, Ames, IA (United States); Takle, Eugene S. [Iowa State University, Department of Geological and Atmospheric Sciences, Ames, IA (United States); Iowa State University, Department of Agronomy, Ames, IA (United States)

    2011-04-15

    Propagating convective storms across the US northern plains are often coupled with preexisting midtropospheric perturbations (MPs) initiated over the Rocky Mountains. A companion study (Part I) notes that such MPs occur most commonly at 12 UTC (early morning) and 00 UTC (late afternoon). Using a regional reanalysis and a general circulation model (GCM), this study investigates how such a bimodal distribution of the MP frequency is formed. The results point to two possible mechanisms working together while each has a different timing in terms of maximum effect. The diurnal evolutions between the midtropospheric flows over the Rockies and over the Great Plains are nearly out-of-phase due to inertial oscillation. During the nighttime, the westerly flows at 700-500 mb over the Rockies intensify while flows at the same level over the Great Plains turn easterly. These two flows converge over the eastern Rockies and induce cyclonic vorticity through vortex stretching. After sunrise, the convergence dissipates and the cyclonic vorticity is redistributed by horizontal vorticity advection, moving it downstream. This process creates a climatological zonally propagating vorticity signal which, in turn, facilitates the early-morning MP genesis at 12 UTC. The analysis also reveals marked dynamic instability conducive to subsynoptic-scale disturbances in the midtroposphere over the Rockies. Strong meridional temperature gradients appear over the north-facing slopes of the Rockies due to terrain heating to the south and the presence of cooler air to the north. This feature, along with persistent vertical shear, creates a Charney-Stern type of instability (i.e. sign changes of the meridional potential vorticity gradient). Meanwhile, the development of terrain boundary layer reduces the Rossby deformation radius which, subsequently, enhances the likelihood for baroclinic short waves. Such effects are most pronounced in the late afternoon and therefore are supportive to the MP

  20. Molecular nuclear imaging of tumoral angio genesis using a rgd-containing tracer, Raft-RGD, targeted at the neo vessel-specific integrin αvβ3

    International Nuclear Information System (INIS)

    Sancey, L.

    2006-06-01

    Tumoral neo-angio genesis targeting is currently a major field of research for the diagnostic and treatment of solid tumors. Endothelial cells from neo vessels over express several specific markers such as the α v β 3 integrin, which binds RGD (-Arg-Gly-Asp-)- containing peptides. We evaluated the potential of a novel radiotracer - RAFT-RGD - for the molecular nuclear imaging of neo vessels. In vitro, the coupling of 4 c(RGDfK) to the RAFT platform resulted in an increased cellular uptake of the tracer by α v β 3 positive cells when compared to c(RGDfK). Furthermore, RAFTRGD has a higher affinity than c(RGDfK) and similar properties for angio genesis inhibition. In vivo, both α v β 3 positive and negative tumors were visible by non invasive whole body planar and tomographic imaging from 30 min to 24 h post-injection, using a gamma camera dedicated to small animal imaging. Despite a lack of significant contrast improvement compare with c(RGDfK), RAFT-RGD could represent a promising tracer for tumoral angio genesis since it could provide invaluable information about tumor development and treatment efficacy in Nuclear Medicine departments. Furthermore, thanks to its chemical structure, RAFT-RGD can be labelled with a variety of radioisotopes including γ and β - emitters, allowing interesting therapeutical applications such as internal targeted radiotherapy. (author)

  1. The ESR age of Portlandia arctica shells from glacial deposits of Central Latvia . an answer to a controversy on the age and genesis of their enclosing sediments

    Science.gov (United States)

    Molodkov, Anatoly; Dreimanis, Aleksis; ĀBoltiņš, Ojars; Raukas, Anto

    The occurrence of Portlandia arctica shells in glacigenic sediments of Central Latvia had created a controversy in many publications about (1) their age ranging from the Holsteinian to the Late Weichselian and (2) the genesis of their enclosing sediments: glacial, glaciomarine or marine. Our reinvestigation of the main object of controversy, the Lı¯čupe site, leads to a conclusion that the sedimentary package of diamictons, clays and sands containing Portlandia arctica shells and marine microfossils is a large glacial raft that had been transported and deposited by the Riga lobe during the Weichselian. The electron spin resonance (ESR) ages on five sets of Portlandia arctica shells from the Lı¯čupe and Daugmales Tomēni sites range from 86.0±6.8 to 105.0±9.2 ka BP. These ESR age determinations and the cool climate indicators of the associated microflora and microfauna suggest that their source sediments, probably in the Gulf of Riga, are marine clays of Early Weichselian age, probably correlative to the Brørup Interstadial. In Central Latvia Portlandia arctica shells and their enclosing clay occur resedimented or translocated in glacial deposits during Weichselian glacial advances.

  2. Long-chain polyunsaturated fatty acids (LCPUFA) from genesis to senescence: the influence of LCPUFA on neural development, aging, and neurodegeneration.

    Science.gov (United States)

    Janssen, Carola I F; Kiliaan, Amanda J

    2014-01-01

    Many clinical and animal studies demonstrate the importance of long-chain polyunsaturated fatty acids (LCPUFA) in neural development and neurodegeneration. This review will focus on involvement of LCPUFA from genesis to senescence. The LCPUFA docosahexaenoic acid and arachidonic acid are important components of neuronal membranes, while eicosapentaenoic acid, docosahexaenoic acid, and arachidonic acid also affect cardiovascular health and inflammation. In neural development, LCPUFA deficiency can lead to severe disorders like schizophrenia and attention deficit hyperactivity disorder. Perinatal LCPUFA supplementation demonstrated beneficial effects in neural development in humans and rodents resulting in improved cognition and sensorimotor integration. In normal aging, the effect of LCPUFA on prevention of cognitive impairment will be discussed. LCPUFA are important for neuronal membrane integrity and function, and also contribute in prevention of brain hypoperfusion. Cerebral perfusion can be compromised as result of obesity, cerebrovascular disease, hypertension, or diabetes mellitus type 2. Last, we will focus on the role of LCPUFA in most common neurodegenerative diseases like Alzheimer's disease and Parkinson's disease. These disorders are characterized by impaired cognition and connectivity and both clinical and animal supplementation studies have shown the potential of LCPUFA to decrease neurodegeneration and inflammation. This review shows that LCPUFA are essential throughout life. Copyright © 2013 Elsevier Ltd. All rights reserved.

  3. Using the GENESYS model quantifying the effect of cropping systems on gene escape from GM rape varieties to evaluate and design cropping systems

    Directory of Open Access Journals (Sweden)

    Colbach Nathalie

    2004-01-01

    Full Text Available Gene flow in rapeseed is a process taking place both in space and over the years and cannot be studied exclusively by field trials. Consequently, the GENESYS model was developed to quantify the effects of cropping systems on transgene escape from rapeseed crops to rapeseed volunteers in neighbour plots and in the subsequent crops. In the present work, this model was used to evaluate the risk of rape harvest contamination by extraneous genes in various farming systems in case of co-existing GM, conventional and organic crops. When 50 % of the rape varieties in the region were transgenic, the rate of GM seeds in non-GM crop harvests on farms with large fields was lower than the 0.9 % purity threshold proposed by the EC for rape crop production (food and feed harvests, but on farms with smaller fields, the threshold was exceeded. Harvest impurity increased in organic farms, mainly because of their small field size. The model was then used to evaluate the consequences of changes in farming practices and to identify those changes reducing harvest contamination. The effects of these changes depended on the field pattern and farming system. The most efficient practices in limiting harvest impurity comprised improved set-aside management by sowing a cover crop in spring on all set-aside fields in the region, permanently banning rape crops and set-aside around seed production fields and (for non-GM farmers clustering farm fields to reduce gene inflow from neighbour fields.

  4. Genesis of a novel Shigella flexneri serotype by sequential infection of serotype-converting bacteriophages SfX and SfI

    Directory of Open Access Journals (Sweden)

    Sun Qiangzheng

    2011-12-01

    Full Text Available Abstract Background Shigella flexneri is the major pathogen causing bacillary dysentery. Fifteen serotypes have been recognized up to now. The genesis of new S. flexneri serotypes is commonly mediated by serotype-converting bacteriophages. Untypeable or novel serotypes from natural infections had been reported worldwide but have not been generated in laboratory. Results A new S. flexneri serotype-serotype 1 d was generated when a S. flexneri serotype Y strain (native LPS was sequentially infected with 2 serotype-converting bacteriophages, SfX first and then SfI. The new serotype 1 d strain agglutinated with both serotype X-specific anti-7;8 grouping serum and serotype 1a-specific anti- I typing serum, and differed from subserotypes 1a, 1b and 1c. Twenty four S. flexneri clinical isolates of serotype X were all converted to serotype 1 d by infection with phage SfI. PCR and sequencing revealed that SfI and SfX were integrated in tandem into the proA-yaiC region of the host chromosome. Conclusions These findings suggest a new S. flexneri serotype could be created in nature. Such a conversion may be constrained by susceptibility of a strain to infection by a given serotype-converting bacteriophage. This finding has significant implications in the emergence of new S. flexneri serotypes in nature.

  5. The contribution of the young Cretaceous Caribbean Oceanic Plateau to the genesis of late Cretaceous arc magmatism in the Cordillera Occidental of Ecuador

    Science.gov (United States)

    Allibon, J.; Monjoie, P.; Lapierre, H.; Jaillard, E.; Bussy, F.; Bosch, D.; Senebier, F.

    2008-12-01

    The eastern part of the Cordillera Occidental of Ecuador comprises thick buoyant oceanic plateaus associated with island-arc tholeiites and subduction-related calc-alkaline series, accreted to the Ecuadorian Continental Margin from Late Cretaceous to Eocene times. One of these plateau sequences, the Guaranda Oceanic Plateau is considered as remnant of the Caribbean-Colombian Oceanic Province (CCOP) accreted to the Ecuadorian Margin in the Maastrichtien. Samples studied in this paper were taken from four cross-sections through two arc-sequences in the northern part of the Cordillera Occidental of Ecuador, dated as (Río Cala) or ascribed to (Macuchi) the Late Cretaceous and one arc-like sequence in the Chogòn-Colonche Cordillera (Las Orquídeas). These three island-arcs can clearly be identified and rest conformably on the CCOP. In all four localities, basalts with abundant large clinopyroxene phenocrysts can be found, mimicking a picritic or ankaramitic facies. This mineralogical particularity, although not uncommon in island arc lavas, hints at a contribution of the CCOP in the genesis of these island arc rocks. The complete petrological and geochemical study of these rocks reveals that some have a primitive island-arc nature (MgO values range from 6 to 11 wt.%). Studied samples display marked Nb, Ta and Ti negative anomalies relative to the adjacent elements in the spidergrams characteristic of subduction-related magmatism. These rocks are LREE-enriched and their clinopyroxenes show a tholeiitic affinity (FeO T-TiO 2 enrichment and CaO depletion from core to rim within a single crystal). The four sampled cross-sections through the island-arc sequences display homogeneous initial Nd, and Pb isotope ratios that suggest a unique mantellic source for these rocks resulting from the mixing of three components: an East-Pacific MORB end-member, an enriched pelagic sediment component, and a HIMU component carried by the CCOP. Indeed, the ankaramite and Mg

  6. Features of the mental status of patients with community-acquired pneumonia, combined with a chronic pathology of the hepatobiliary system of non-viral genesis

    Directory of Open Access Journals (Sweden)

    Razumnyi R.V.

    2017-04-01

    Full Text Available The aim was to study the characteristics of mental status of patients with community-acquired pneumonia (CAP, combined with a chronic pathology of the hepatobiliary system of non-viral genesis. We observed 165 patients with CAP in the age of 25-57 years. All patients were divided into two representative groups: I group (68 patients – CAP was comorbid with hepatic steatosis (HS, II group (96 patients with absence of chronic liver disease. To evaluate the psychological profile of patients’ personality we used a standardized multivariate method of personality research and to evaluate the level of anxiety and depression the scale of Spielberger-Hanin test and Beck’s questionnaire were used. Results of the study revealed that 66.2% of patients with CAP, comorbid with HS, declared the formation of psycho-emotional disorders in the form of neurotic reactions to the disease with prevalence of hypochondria, depression, hysterical manifestations with high psychasthenia, trait anxiety and somatic reactions with prevalence of anxiety and emotional instability, lots of somatic complaints, fixation on their own condition with formation of distinctive thinking mode and behavior by the type of "flight into disease". After completion of the standard treatment of patients with CAP, combined with HS, 42,7% of patients had psycho-emotional disorders, which were moderately expressed. Thus, in the complex of treatment and rehabilitative measures in patients with CAP, combined with HS some characteristics of the psychological profile, in the form of psycho-neurotic reaction to the disease should be considered to take optimal corrective actions.

  7. The genesis of breast cancer is a two-step phenomenon. II. Dissociation of two biomarkers in cancer patients from a low risk area of Japan.

    Science.gov (United States)

    Kodama, M; Kodama, T; Murakami, M; Kobayashi, S; Akita, T; Nakamura, Y

    1992-01-01

    The association of dual steroidal disorders with breast cancer, as proposed on the basis of a case-control study in a high risk area of Japan, was tested for its validity in breast cancer patients from a low risk area of Japan. A state of glucocorticoid excess, the first hormonal trait of a breast cancer patient, was assessed using a urinary steroid parameter (a reduction of the androsterone to tetrahydrocortisol ratio by definition), and/or using a physical parameter (an elevation of the waist to hip circumference ratio by definition). Inclination to ovulation failure, the second hormonal trait, was tested using another urinary steroid parameter (a specified disorder of progestin metabolism by definition), and/or a demographic parameter (a reduction in the number of live births by definition). Results obtained are as follows: 1) premenopausal breast cancer patients from a low risk area were found to have the second trait but not the first trait, as tested using 2 parameters for each trait. 2) Postmenopausal cancer patients from a low risk area as well as pre- and post-menopausal cancer patients from a high risk area had both the 2 hormonal traits. 3) There was no discrepancy of results between any 2 test systems with the identification of 2 hormonal traits in 4 cancer patient groups. The significance of the dissociation of 2 hormonal traits, as observed in premenopausal cancer patients from a low risk area, is discussed in favor of the two-step carcinogenesis theory. Possible interaction of heredity and environment in the genesis of breast cancer is also taken into consideration.

  8. [pH values in the pharynx of the patients presenting with compromised nasal breathing of inflammatory and non-inflammatory genesis concomitant with gastroesophageal reflux disease].

    Science.gov (United States)

    Subbotina, M V; Temnikova, I V; Onuchina, E V

    2015-01-01

    The objective of the present study was to estimate the influence of gastroesophageal reflux disease (GERD) on the pH values in the pharynx and nose. It included 87 patients at the age varying from 18 to 81 years admitted to the Irkutsk-based Railway Clinical Hospital and allocated to four groups. Group 1 was comprised of 25 patients presenting with gastroesophageal reflux disease and chronic rhinosinusitis (CRS), group 2 consisted of 29 patients with CRS in the absence of GERD, group 3 included 22 patients with nasal septum deformations (NSD) and GERD, group 4 included 11 patients with NSD and motor rhinitis without GERD. The control group was formed from 10 volunteers. pH was measured by the contact method with the use ofEkokhim indicator paper. Gastroesophageal reflux disease was diagnosed following the recommendations of the Montreal consensus. It was shown that pH values in the pharynx of the patients with compromised nasal breathing of any origin in combination with GERD were lower than in the absence of GERD and in the healthy volunteers. The study groups did not differ in terms of pH values in the nasal cavity. It is concluded that pH values 4 or lower may serve as the criterion for pharyngo-laryngeal reflux (PLR) concomitant with HERD while pH 5 occurs more frequently in the patients with compromised nasal breathing of any etiology, regardless of the presence or absence of GERD.Disordered nasal breathing of any genesis in the patients presenting with gastroesophageal reflux disease was associated with the feeling of the lump in the throat, congestion of the respiratory tract and the nose, pain in the ears, cardialgia, and irregular heartbeat. It isrecommended to use pH measurements as a criterion for diagnostics of pharyngo-laryngeal reflux in the patients presenting with gastroesophageal reflux disease.

  9. Towards universal health coverage in India: a historical examination of the genesis of Rashtriya Swasthya Bima Yojana - The health insurance scheme for low-income groups.

    Science.gov (United States)

    Virk, A K; Atun, R

    2015-06-01

    Many low- and middle-income countries have introduced State-funded health programmes for vulnerable groups as part of global efforts to universalise health coverage. Similarly, India introduced the Rashtriya Swasthya Bima Yojana (RSBY) in 2008, a publicly-funded national health insurance scheme for people below the poverty line. The authors explore the RSBY's genesis and early development in order to understand its conceptualisation and design principles and thereby establish a baseline for assessing RSBY's performance in the future. Qualitative case study of the RSBY in Delhi. This paper presents results from documentary analysis and semi-structured interviews with senior-level policymakers including the former Labour Minister, central government officials and affiliates, and technical specialists from the World Bank and GIZ. With national priorities focused on broader economic development goals, the RSBY was conceptualised as a social investment in worker productivity and future economic growth in India. Hence, efficiency, competition, and individual choice rather than human needs or egalitarian access were overriding concerns for RSBY designers. This measured approach was strongly reflected in RSBY's financing and benefit structure. Hence, the programme's focus on only the 'poorest' (BPL) among the poor. Similarly, only costlier forms of care, secondary treatments in hospitals, which policymakers felt were more likely to have catastrophic financial consequences for users were covered. This paper highlights the risks of a narrow approach driven by developmental considerations alone. Expanding access and improving financial protection in India and elsewhere requires a more balanced approach and evidence-informed health policies that are guided by local morbidity and health spending patterns. Copyright © 2015 The Royal Society for Public Health. Published by Elsevier Ltd. All rights reserved.

  10. Diagenesis of amorphous organic matter as an essential aspect of genesis and alteration of tabular-type uranium-vanadium deposits, Colorado Plateau

    International Nuclear Information System (INIS)

    Spirakis, C.S.; Hansley, P.L.

    1987-01-01

    Organic matter was the key to the initial concentration of uranium and vanadium (during the sulfate reduction stage of early diagenesis) in all sandstone-hosted, tabular deposits in the Morrison Formation, Colorado Plateau. In deposits rich in amorphous organic matter, as are many in the Grants uranium region (GUR), diagenesis did not proceed beyond sulfate reduction. In contrast, in organic-poor, chlorite deposits of the Henry Mountains district, 13 C- and 18 O-enriched dolomites preserve evidence of a subsequent methanogenic stage. In these and similar organic-poor deposits in the Slick Rock district and in parts of the GUR, aluminosilicate dissolution (including a distinctive, organic-acid-induced etching of garnets) and growth of coarse-grained coffinite, albite, ankerite, and chlorite suggest diagenesis reached the organic acid stage. Temperature and thermal maturation indicators (vitrinite reflectance, type IIb chlorite, ordered illite/smectite, and fluid inclusion data) are consistent with temperatures of organic-acid stage diagenesis (∼ 100 0 C). The localization of these alterations in and around organic-poor, clay-rich ore; the similarities in type and sequence of these alterations to the normal alteration of organic-bearing sediments; the alteration of iron-titanium oxides (attributed to the action of soluble organic complexes) around both organic-rich and organic-poor deposits; and the gradation from organic-rich to organic-poor, chlorite-rich deposits (in GUR) suggest that (1) amorphous organic matter was involved in the genesis of all of these deposits and (2) differences among deposits may reflect varying degrees of diagenesis of the organic matter

  11. GENESIS OF THE PLOT AND THE GENRE OF THE CREATIVE HISTORY OF SHMELEV’S SHORT NOVEL “TOWARD A NEW LIFE”

    Directory of Open Access Journals (Sweden)

    Oksana A. Sosnovskaya

    2015-11-01

    Full Text Available Th e beginning of  Shmelev’s career is associated with children’s literature. In the early 20th century, the writer creates a signifi cant number of  works for children, published in  magazines for young people. In  one of these magazines — “Young Russia” — there was published Shmelev’s story Toward a  new life. Th e article is  devoted to studying the creative history of this story: following the process of origin and genesis of an artistic idea of the text, analyzing the stages of its creation, editions and poetics. Th e working process had two phases and found its refl ection in three editions of the story. At the fi rst stage the writer was working upon a  sketch of the life of contemporary villages. Later this essay became a prehistory of the short novel about a country boy torn out of his ambiance and seeking for his way in life. Not only the genre changed but the  ideological content of the work became extended as well. Th e core idea of the author that is present throughout the story is the idea of scientifi c perception of nature and life, receiving education that is able to improve life of a common man. In the story Toward a new life, focused on representing a social aspect of life, there are revealed the beginnings of the author’s original writing manner, his unique style and language.

  12. Preaching the ‘green gospel’ in our environment: A re-reading of Genesis 1:27-28 in the Nigerian context

    Directory of Open Access Journals (Sweden)

    Chris Manus

    2016-08-01

    Full Text Available The article focuses on the text of Genesis 1:27–28 within its broader context where the author, the Jahwist, describes humankind as charged with the responsibility to fill and to subdue the earth, which has generally been misunderstood by wealth prospectors. Our methodology is a simplified historical and exegetical study of the two verses of the creation narrative in order to join other contemporary theologians to argue the right of humans to treat the nonhuman as private property as source of material wealth is immoral. As we re-read the text, our findings resonate with the contemporary clarion call for respect and protection of the environment such as COP 2015 in Paris. This provides the justification of our title ‘Preaching the green gospel’, especially in the Nigerian oil-rich states and in Africa in general. Whilst the paper presents a disquisition of the global efforts of the church through sensitisation of their members to appreciate the magnitude of the environmental pollution and the apocalypse it holds for the world, it draws attention to the possibility of the envisaged doomsday that may descend on Nigeria and other parts of Africa if the crass environmental degradation and the rate of pollution of flora and fauna are not checked. The paper takes cognisance of the positive views expressed by the evangelists of the ‘New Theology’ in Africa. Whilst the paper raises Biblically friendly ecological awareness in modern Africa, using Nigeria as a contact point, it concludes, inter alia, that the text demands humankind to partake in God’s will for order and peace in the universe as it struggles to maintain the ecological sustainability of mother earth.

  13. Petrological and geochemical features of the early Paleozoic granitic gneisses and iron ores in the Tianhu iron deposit, Eastern Tianshan, NW China: Implications for ore genesis

    Science.gov (United States)

    Zheng, Jiahao; Mao, Jingwen; Yang, Fuquan; Chai, Fengmei; Shen, Ping

    2017-08-01

    This paper reports whole-rock geochemical, zircon U-Pb and Hf isotopic data for ore-hosted granitic gneisses, mineral compositions of oxides, and sulfur isotopic data for sulfides in iron ores from the Tianhu deposit, central part of the Eastern Tianshan. Our results can provide crucial constraints on the genesis of granitic gneisses and early Paleozoic tectonic setting of the Eastern Tianshan. LA-ICP-MS U-Pb dating on magmatic zircons yielded weighted mean 206Pb/238U ages of 463 to 438 Ma, interpreted as the crystallization ages of the granitic protoliths and the formation ages of the Tianhu Group. Zircon U-Pb age of ore-hosted granitic gneiss (ca. 459 Ma) can provide reliable constrains on upper limit for iron mineralization age in the Tianhu deposit. Geochemical characteristics suggest that the protoliths of the Tianhu granitic gneisses are metaluminous to weakly peraluminous high-K calc-alkaline granitic rocks, exhibiting typical subduction-related features such as strong enrichment in LREE and LILE and depletion in HFSE. Zircon Hf isotopic compositions show a positive trend from 463 to 438 Ma, indicating that 460 Ma magmas came from both ancient and juvenile sources, whereas 438 Ma magmas involved more juvenile material. Some early Paleozoic granitoids were recently identified in the Eastern Tianshan with the ages between ca. 475 and ca. 425 Ma. The formation of these early Paleozoic granitoids was in response to subduction processes, suggesting that subduction of Junggar Ocean probably began in the Early Ordovician and lasted until Late Silurian. Pyrite and pyrrhotite in iron ores have δ34SCDT values from + 4.6 to + 15.7‰, which are consistent with the marine source, but inconsistent with the magmatic source or those involved evaporites in skarn iron deposit. Geological, geochemical, and isotopic data suggest that the Tianhu iron ores were formed by volcano-sedimentary processes in a subduction environment during the early Paleozoic time, and Tianhu is a

  14. Study Of The Rupture Process Of The 2015 Mw7.8 Izu-Bonin Earthquake And Its Implication To Deep-Focus Earthquake Genesis.

    Science.gov (United States)

    Jian, P. R.; Hung, S. H.; Meng, L.

    2015-12-01

    length of 15-20 km and weaker radiated energy. The overall rupture speed is about 1.5-2 km/s. As it rarely struck the area close to the outer periphery of the slab under the condition of relatively high-temperature and downdip extension, thermally-induced shear instability may play an important role in the genesis of this deep-focus earthquake.

  15. Sedimentary mode and reservoir genesis of dual grain banks at the Lower Cambrian Longwangmiao Fm carbonate ramp in the Sichuan Basin

    Directory of Open Access Journals (Sweden)

    Jinhu Du

    2016-11-01

    Full Text Available The gas reservoir of the Lower Cambrian Longwangmiao Fm in the Sichuan Basin is a supergiant integral marine carbonate gas reservoir whose single scale is currently the largest in China. In order to figure out its sedimentary model and reservoir genesis, its geological structures and sedimentary settings and facies were analyzed comprehensively and the lithofacies paleographic map was plotted. It is revealed that the following sedimentary facies are successively developed in the Longwangmiao Fm from West Sichuan to Southeast Chongqing: diamictic tidal flat at the back ramp, grain bank (the upper bank at the inner/shallow ramp – interbank sea (depression, deeper open bay at the platform depression of inner ramp → evaporative lagoon → evaporative tidal flat, tempestite at the middle ramp – barrier beach – mud mound beach (the lower bank, and outer ramp – basin. Accordingly, the specific sedimentary model of dual grain banks in the Longwangmiao Fm carbonate ramp was established as follows. Firstly, in this model, dual grain banks are symmetrically developed with Wanzhou–Yibin platform depression as the axis, on whose dual sides the paleohighs have shallow water bodies with strong energy. Compared with the classical model, the new one has a new upper bank which is developed around the paleohighs covering an area of about 8 × 104 km2. Secondly, the upper bank is large for its paleogeomorphology being located at the highest position with the strongest water energy during deposition. Therefore, it is prone to dolomitization and meteoric dissolution respectively during contemporaneous–penecontemporaneous hot-dry and hot-humid periods, and especially the Caledonian–Early Hercynian denudation wedge out tends to undergo post-supergene multiphase karstification. Therefore, quality reservoirs are more developed on scale. Thirdly, the intergranular pores and vermes moldic pores were dissolved and enlarged due to the multiphase

  16. Development and characterization of a hydrogen peroxide-resistant cholangiocyte cell line: A novel model of oxidative stress-related cholangiocarcinoma genesis

    Energy Technology Data Exchange (ETDEWEB)

    Thanan, Raynoo [Department of Biochemistry, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002 (Thailand); Liver Fluke and Cholangiocarcinoma Research Center, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002 (Thailand); Techasen, Anchalee [Liver Fluke and Cholangiocarcinoma Research Center, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002 (Thailand); Faculty of Associated Medical Science, Khon Kaen University, Khon Kaen 40002 (Thailand); Hou, Bo [Department of Environmental and Molecular Medicine, Mie University Graduate School of Medicine, Tsu, Mie 514-8507 (Japan); Jamnongkan, Wassana; Armartmuntree, Napat [Department of Biochemistry, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002 (Thailand); Liver Fluke and Cholangiocarcinoma Research Center, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002 (Thailand); Yongvanit, Puangrat, E-mail: puangrat@kku.ac.th [Department of Biochemistry, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002 (Thailand); Liver Fluke and Cholangiocarcinoma Research Center, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002 (Thailand); Murata, Mariko, E-mail: mmurata@doc.medic.mie-u.ac.jp [Department of Environmental and Molecular Medicine, Mie University Graduate School of Medicine, Tsu, Mie 514-8507 (Japan)

    2015-08-14

    Oxidative stress is a cause of inflammation–related diseases, including cancers. Cholangiocarcinoma is a liver cancer with bile duct epithelial cell phenotypes. Our previous studies in animal and human models indicated that oxidative stress is a major cause of cholangiocarcinoma development. Hydrogen peroxide (H{sub 2}O{sub 2}) can generate hydroxyl radicals, which damage lipids, proteins, and nucleic acids, leading to cell death. However, some cells can survive by adapting to oxidative stress conditions, and selective clonal expansion of these resistant cells would be involved in oxidative stress-related carcinogenesis. The present study aimed to establish H{sub 2}O{sub 2}-resistant cell line from an immortal cholangiocyte cell line (MMNK1) by chronic treatment with low-concentration H{sub 2}O{sub 2} (25 μM). After 72 days of induction, H{sub 2}O{sub 2}-resistant cell lines (ox-MMNK1-L) were obtained. The ox-MMNK1-L cell line showed H{sub 2}O{sub 2}-resistant properties, increasing the expression of the anti-oxidant genes catalase (CAT), superoxide dismutase-1 (SOD1), superoxide dismutase-2 (SOD2), and superoxide dismutase-3 (SOD3) and the enzyme activities of CAT and intracellular SODs. Furthermore, the resistant cells showed increased expression levels of an epigenetics-related gene, DNA methyltransferase-1 (DNMT1), when compared to the parental cells. Interestingly, the ox-MMNK1-L cell line had a significantly higher cell proliferation rate than the MMNK1 normal cell line. Moreover, ox-MMNK1-L cells showed pseudopodia formation and the loss of cell-to-cell adhesion (multi-layers) under additional oxidative stress (100 μM H{sub 2}O{sub 2}). These findings suggest that H{sub 2}O{sub 2}-resistant cells can be used as a model of oxidative stress-related cholangiocarcinoma genesis through molecular changes such as alteration of gene expression and epigenetic changes. - Highlights: • An H{sub 2}O{sub 2}-resistant ox-MMNK1-L cells was established from

  17. Genesis and servitudes of nuclear

    International Nuclear Information System (INIS)

    Debeir, Jean-Claude; Deleage, Jean-Paul; Hemery, Daniel

    2011-01-01

    This article is a chapter of a book published by the authors after the catastrophe of Chernobyl. They first propose a history of nuclear in four main stages: first, from the atom of physicists to the bomb (1932-1942), second, the bomb, and the American policy of atomic monopoly and its failure (1940-1956), third, the beginnings of the nuclear energy (1952-1969), and the recession (1974-?). Then, they discuss electro-nuclear energy as the last energetic component of the capital accumulation regime based on mass consumption and issued the great depression of the 1930's. In the next part, they identify some historical peculiarities of nuclear, notably with an emergence of discontinuities in the energetic process, the power to the science, the joining between the energy system and the war system, the nationalisation of energy, and the trend in capital valorisation and restructuring

  18. Genesis of enterprise financial security

    Directory of Open Access Journals (Sweden)

    Davydenko N. M.

    2015-05-01

    Full Text Available The article analyzes the scientific approaches to the definition of «financial security of entities», advantages and disadvantages of these approaches are highlighted. The own definition of financial security of entities is given. The composition of elements of enterprise financial security and principles of its provision are defined. Тhe role of individual elements of financial security to ensure high efficiency operation and development of enterprises is significant and has a direct impact on their solvency, liquidity and profitability.

  19. Modelling the Genesis and Evolution

    DEFF Research Database (Denmark)

    Hjelholt, Morten; Damsgaard, Jan

    Over the last three decades, EU regulation of the internal market has become highly pervasive, affecting practically all the domains of European citizens’ lives. Many studies have focused on understanding the process and causes of regulatory reform. However, these have typically been small...

  20. The genesis of general relativity

    CERN Document Server

    Norton, John; Renn, Jürgen; Sauer, Tilman; Stachel, John

    2007-01-01

    This four-volume work represents the most comprehensive documentation and study of the creation of general relativity; one of the fundamental physical theories of the 20th century. It comprises key sources from Einstein and others who from the late 19th to the early 20th century contributed to this monumental development. Some of these sources are presented here in translation for the first time. Einstein’s famous Zurich notebook, which documents the pivotal steps toward general relativity, is reproduced here for the first time and transcribed in its entirety. The volumes offer detailed commentaries and analyses of these sources that are based on a close reading of these documents supplemented by interpretations by the leading historians of relativity. All in all, the facets of this work, based on more than a decade of research, combine to constitute one of the most in-depth studies of a scientific revolution ever written.

  1. Quantum cosmology - science of Genesis

    International Nuclear Information System (INIS)

    Padmanabhan, Thanu

    1987-01-01

    Quantum cosmology, the marriage between the theories of the microscopic and macroscopic Universe, is examined in an attempt to explain the birth of the Universe in the 'big bang'. A quantum cosmological model of the Universe does not exist, but a rough approximation, or 'poor man's' version of quantum cosmology has been developed. The idea is to combine the theory of quantum mechanics with the classical cosmological solutions to obtain a quantum mechanical version of cosmology. Such a model of quantum cosmology is described -here the quantum universe behaves like a hydrogen atom with the Planck length replacing the Bohr radius. Properties of quantum cosmologies and the significance of the Planck length are both discussed. (UK)

  2. Towards Genesis or the Grave

    DEFF Research Database (Denmark)

    Hansen, Sune Welling

    The paper outlines a theoretical framework for understanding reform-related opportunism in connection with current local government mergers in Denmark. The chain of reasoning is based on a local government version of the political business cycle. Where this model predicts cyclical financial patte...... and group level). This is achieved with the aid of insights from collective action theory.......The paper outlines a theoretical framework for understanding reform-related opportunism in connection with current local government mergers in Denmark. The chain of reasoning is based on a local government version of the political business cycle. Where this model predicts cyclical financial...... patterns on reversible financial expenditures within each election period, the developed argument on local government mergers posits a pattern on non-reversible expenditures in the immediate years preceding them. The paper utilizes a theory-testing design with explanatory factors on two levels (individual...

  3. Osteoarthritis: the genesis of pain.

    Science.gov (United States)

    Fu, Kai; Robbins, Sarah R; McDougall, Jason J

    2018-05-01

    OA is a painful joint disease that predominantly affects the elderly. Pain is the primary symptom of OA, and it can present as either intermittent or constant. OA pain mechanisms are complex and have only recently been determined. Both peripheral and central processes are involved in creating the OA pain experience, making targeted therapy problematic. Nociceptive, inflammatory and neuropathic pains are all known to occur in OA, but to varying degrees in a patient- and time-specific manner. A better understanding of these multifactorial components of OA pain will lead to the development of more effective and safer pain treatments.

  4. Towards Genesis or the Grave

    DEFF Research Database (Denmark)

    Hansen, Sune Welling

    -beens can lead to decidedly myopic and short-sighted behavior in spite of its longer-term consequences. So much for actor incentives! On the institutional side, the incumbent government has, in contrast to its forty-year-old likewise bourgeois predecessor, been all too aware of these ‘perverse' incentives......' financial behavior stand out in the period leading up to the second local government reform - and if so then why? As will be explicated in later chapters, the measuring rod for ‘standing out' will be both temporal (compared to the authorities' financial dispositions in previous years) and spatial (compared......' financial dispositions as liquidity, near-liquid assets (sales of buildings, land and so forth), expenditures on buildings and probably also operations, borrowing, public utilities and expenditures on personnel....

  5. Genesis of a bad idea

    Science.gov (United States)

    Carlowicz, Michael

    According to an article in Business Week (June 10), Macmillan/McGraw-Hill Inc. has agreed to custom-publish a version of its fourth-grade textbook Changing Earth in order to omit a chapter entitled “Birth of Earth.” Parents in the Cobb County, Georgia, school district complained that since the chapter does not include creationism as a theory for the origin of the universe and of Earth, the entire discussion ought to be left out.According to McGraw-Hill, customizing its textbooks is good business. Changing Earth and other such books are designed to allow teachers to build their own programs; the company is willing to customize texts because it does not want to dictate curricula, and it tries to meet demands of school districts. Business Week noted that the theory of evolution still is taught in the sixth and eighth grades, as well as high school, in Cobb County. Changing Earth also contains references to evolution in other chapters besides the one being deleted.

  6. Microsporogênese em clones normais e tetraplóides de Hevea brasiliensis Muell.-Arg Microsporo genesis in normal and tetraploid Hevea brasiliensis (Muell.-Arg.

    Directory of Open Access Journals (Sweden)

    Cândida H. T. M. Conagin

    1971-01-01

    Full Text Available Pesquisas sôbre o efeito da colquicina em Hevea brasiliensis Muell.-Arg. realizadas anteriormente levaram à obtenção de clones com número duplicado de cromossomos; tais clones, atualmente em fase de amplas e detalhadas observações (6, floresceram em 1969, pela primeira vez. Foi então realizado um estudo citológico comparativo da microsporo-gènese de duas plantas, uma pertencente ao clone normal n.° 3064, com 2n = 36 cromossomos, e outra pertencente ao clone duplicado n.° 3065, com 2n=72 cromossomos. Ambos são considerados clones gêmeos, porque foram obtidos de uma mesma semente, por técnica especial (7. Na planta com 2n = 36 cromossomos, o processo meiótico é normal, dando tétrades perfeitas e grãos de pólen aparentemente funcionais. A planta 3065, com 2n=72 cromossomos, apresenta, além de células-mães de pólen que se dividem normalmente, outras que no final da meiose produzem tétrades anormais, com micrócitos excedentes e grãos de pólen vazios. Caracteriza-se também por grãos de pólen que não passam pelas divisões mitóticas, isto é, apresentam sempre um núcleo só, que não se divide. Em virtude destas primeiras observações pode-se formular uma hipótese de esterilidade masculina para o clone em estudo.Previous works on Hevea brasiliensis Muell.-Arg. produced several pairs of twin clones, one member having the normal chromosome number and the other the duplicated set after colchicine treatment. Plants of normal clone 3064 are fertile and have 32 chromosomes. Microsporogenesis is normal, producing only normal tetrads of four microsporocytes. The resulting pollen grains have three germinal pores. Grains in different stages of development could be noticed, from one-nucleated cytoplasm to the two-nucleated reproductive cell, which undoubtedly means normal game to genesis. On the other hand plants of the duplicated twin clone 3065, blossomed during the year of 1969 for the first time. Microsporogenesis studied

  7. O papel dos hormônios leptina e grelina na gênese da obesidade The role of leptin and ghrelin on the genesis of obesity

    Directory of Open Access Journals (Sweden)

    Carla Eduarda Machado Romero

    2006-02-01

    Full Text Available A prevalência da obesidade está aumentando e estudos prospectivos mostram que, em 2025, o Brasil será o quinto país do mundo a apresentar problemas de obesidade em sua população. A etiologia da obesidade não é de fácil identificação, uma vez que a mesma é caracterizada como uma doença multifatorial, ou seja, diversos fatores estão envolvidos em sua gênese, incluindo fatores genéticos, psicológicos, metabólicos e ambientais. Pesquisas recentes na área de metabolismo mostram que o adipócito é capaz de sintetizar várias substâncias e, diferentemente do que se supunha anteriormente, o tecido adiposo não é apenas um sítio de armazenamento de triglicérides, é hoje considerado um órgão endócrino. Dentre as diversas substâncias sintetizadas pelo adipócito, destacam-se a adiponectina, a angiotensina e a leptina. A leptina é um petídeo que desempenha importante papel na regulação da ingestão alimentar e no gasto energético, gerando um aumento na queima de energia e diminuindo a ingestão alimentar. Além dos avanços no estudo da célula adiposa, um novo hormôrnio relacionado ao metabolismo foi descoberto recentemente, a grelina. A grelina é um peptídeo produzido nas células do estômago, e está diretamente envolvida na regulação do balanço energético a curto prazo. Assim, este artigo abordará o papel da leptina e da grelina no controle do peso corporal e as limitações que ainda existem para tratar a obesidade em humanos.The prevalence of obesity is rising around the world and prospective studies show that in 2025, Brazil will be the fifth country in the world to have obesity problems. Multifactorial factors are involved in the genesis of obesity including genetic, psychological, metabolic and environmental factors. Recently, adipocytes have been considered an endocrine tissue capable of producing several substances, including adiponectin, angiotensin and leptin. Leptin is the main peptide produced by

  8. Genesis of diamond inclusions: An integrated cathodoluminescence (CL) and Electron backscatter diffraction (EBSD) study on eclogitic and peridotitic inclusions and their diamond host.

    Science.gov (United States)

    van den Heuvel, Quint; Matveev, Sergei; Drury, Martyn; Gress, Michael; Chinn, Ingrid; Davies, Gareth

    2017-04-01

    inclusions now cut diamond growth zones. In most cases, the growth zonation around inclusions is not well defined due to CL haloes but some inclusions clearly disrupt diamond growth. Crystallographic orientations of diamond and the inclusions, determined using EBSD, revealed that each inclusion has a homogeneous orientation and record no compositional zonation. The diamonds also showed no angular deviations despite many having multiple growth and resorption zones; implying epitaxial growth of diamond. Crystallographic alignment between diamond and inclusions was not recorded for the principle planes and limited to 3 possible coincidences on minor planes from the 24 inclusions studied. The CL data show no evidence of syngenesis for these 3 inclusions. Analyses of two diamonds with inclusion clusters in different growth zones, 400 µm apart, revealed the same chemical composition and orientation, potentially implying they originated from an original larger inclusion. Combined EBSD and CL data suggest that there is no direct orientational correlation (epitaxial growth) between silicate inclusions and the host diamond, even when the mineral phases are of the same symmetry group. The presentation will provide a detailed evaluation of the genesis of individual inclusions.

  9. The role of liquid-liquid immiscibility and crystal fractionation in the genesis of carbonatite magmas: insights from Kerimasi melt inclusions

    Science.gov (United States)

    Guzmics, Tibor; Zajacz, Zoltán; Mitchell, Roger H.; Szabó, Csaba; Wälle, Markus

    2015-02-01

    melt, whereas Mg, Mn, Fe, Co, Cu, Zn, Al, Sc, Ti, Hf and Zr are partitioned into the silicate melt. Potassium and Rb show no preferential partitioning. Kerimasi melt inclusions show that the immiscible calcic carbonate melt is strongly enriched in Sr, Ba, Pb, LREE, P, W, Mo and S relative to other trace elements. Comparison of our data with experimental results indicates that preferential partitioning of oxidized sulfur (as SO4 2-), Ca and P (as PO4 3-) into the carbonate melt may promote the partitioning of Nb, Ta, Pb and all REE, excluding Sc, into this phase. Therefore, it is suggested that P and S enrichment in calcic carbonate magmas promotes the genesis of REE-rich carbonatites by liquid immiscibility. Our study shows that changes in the partition coefficients of elements between minerals and the coexisting melts along the liquid line of descent are rather significant at Kerimasi. This is why, in addition to the REE, Nb, Ta and Zr are also enriched in Kerimasi calciocarbonatites. We consider significant amounts of apatite and perovskite precipitated from melilite-nephelinite-derived carbonate melt as igneous minerals can have high LREE, Nb and Zr contents relative to other carbonatite minerals.

  10. Estudio del proceso de génesis instrumental del artefacto simbólico función exponencial Study of the process of instrumental genesis of the symbolic artifact for the exponential function

    Directory of Open Access Journals (Sweden)

    Mihály André Martínez Miraval

    2018-05-01

    Full Text Available This article describes a study of the exponential function on students of the first semester of a private University in Lima, Peru. The research was aimed at analyzing the Instrumental genesis process of this mathematical object assisted by the use of Geogebra software. Rabardel's Instrumental Approach was used as a theoretical framework. Likewise, some notions of Artigue's Didactic Engineering were used as a methodology, focusing on a priori and a posteriori analysis. The students’ answers allowed to identify the use of schemes built and activated, while interacting with the symbolic artifact for the exponential function. The use of Geogebra favored the instrumentalization and instrumentation of the addressed mathematical object since it allowed the students to validate their conjectures. Keywords:

  11. Biomarcadores asociados a riesgo de síndrome metabólico: estudio en personal médico y administrativo de la Facultad de Ciencias de la Salud UNAB - GENESIS II; --Associated biomarkers with metabolic syndrome risk: A study among medical and administrative staff of the UNAB Health Science Faculty - GENESIS II

    Directory of Open Access Journals (Sweden)

    Norma Cecilia Serrano Díaz, MD, MSc

    2011-01-01

    preventive measures to decrease the occurrence or severity of their consequences. Objectives: To establish the prevalence of MS and to determine the behavior of traditional and no traditional cardiovascular risk factors of men and women from Bucaramanga, Colombia. Methodology: GENESIS is a prospective cohort study in 2005 and 2010 assessment. For the second phase, all participants completed a semistructured questionnaire, received clinical evaluation forblood pressure and anthropometric parameters and peripheral blood sampling for measurement of fasting glucose, cholesterol, HDL, triglycerides, CRP, IL-6, Apo AI and Apo B. Results: 66 employees were evaluated for second phase. The prevalence of MS was 18.2%. Among them, the male population had the highest values of waist circumference, glucose, triglycerides, Apo B and Apo B/Apo AI, compared with women. In Follow-up study, 44 people were assessed on two occasions (2005 and 2010; female population showed a significant increase in waist circumference, cholesterol, HDL and blood glucose levels, and decrease in CRP compared with men. Conclusion: Therecognition of traditional and non-conventional risk factors, andthe differences between genders would help to optimize cardiovascular risk stratification and therefore better prevention of CVD in the future.

  12. Sr-Nd-Pb isotopic constraints on the nature of the mantle sources involved in the genesis of the high-Ti tholeiites from northern Paraná Continental Flood Basalts (Brazil)

    Science.gov (United States)

    Rocha-Júnior, Eduardo R. V.; Marques, Leila S.; Babinski, Marly; Nardy, Antônio J. R.; Figueiredo, Ana M. G.; Machado, Fábio B.

    2013-10-01

    There has been little research on geochemistry and isotopic compositions in tholeiites of the Northern region from the Paraná Continental Flood Basalts (PCFB), one of the largest continental provinces of the world. In order to examine the mantle sources involved in the high-Ti (Pitanga and Paranapanema) basalt genesis, we studied Sr, Nd, and Pb isotopic systematics, and major, minor and incompatible trace element abundances. The REE patterns of the investigated samples (Pitanga and Paranapanema magma type) are similar (parallel to) to those of Island Arc Basalts' REE patterns. The high-Ti basalts investigated in this study have initial (133 Ma) 87Sr/86Sr ratios of 0.70538-0.70642, 143Nd/144Nd of 0.51233-0.51218, 206Pb/204Pb of 17.74-18.25, 207Pb/204Pb of 15.51-15.57, and 208Pb/204Pb of 38.18-38.45. These isotopic compositions do not display any correlation with Nb/Th, Nb/La or P2O5/K2O ratios, which also reflect that these rocks were not significantly affected by low-pressure crustal contamination. The incompatible trace element ratios and Sr-Nd-Pb isotopic compositions of the PCFB tholeiites are different to those found in Tristan da Cunha ocean island rocks, showing that this plume did not play a substantial role in the PCFB genesis. This interpretation is corroborated by previously published osmium isotopic data (initial γOs values range from +1.0 to +2.0 for high-Ti basalts), which also preclude basalt generation by melting of ancient subcontinental lithospheric mantle. The geochemical composition of the northern PCFB may be explained through the involvement of fluids and/or small volume melts related to metasomatic processes. In this context, we propose that the source of these magmas is a mixture of sublithospheric peridotite veined and/or interlayered with mafic components (e.g., pyroxenites or eclogites). The sublithospheric mantle (dominating the osmium isotopic compositions) was very probably enriched by fluids and/or magmas related to the

  13. Os nitritos são importantes na gênese do adenocarcinoma associado ao esôfago de Barrett? Are the nitrites important in a genesis of the adenocarcinoma associated to the Barrett esophagus?

    Directory of Open Access Journals (Sweden)

    Sergio Ferreira Módena

    2008-09-01

    Full Text Available RACIONAL: O esôfago de Barrett é complicação do refluxo gastroesofágico e predispõe ao surgimento do adenocarcinoma, sendo que vários fatores têm sido relacionados à sua etiopatogenia. OBJETIVO: Analisar o modelo experimental de refluxo duodenogastroesofágico e a ingestão de solução de nitrito de sódio na gênese do adenocarcinoma associado ao esôfago de Barrett. MÉTODOS: Sessenta ratos machos Wistar foram divididos em quatro grupos, com 20 animais controles não operados (10 animais ingeriram somente água e 10 água mais solução de nitrito de sódio e 40 animais submetidos à anastomose duodenogastroesofágica látero-lateral (20 animais ingeriram somente água e 20 animais ingeriram água mais solução de nitrito de sódio. A ocorrência de esofagite, metaplasia, displasia, esôfago de Barrett e adenocarcinoma associado foram analisados. A classificação de Viena para displasia e adenocarcinoma foi empregada na análise dos resultados. RESULTADOS: Após 42 semanas de observação, nos animais operados sem ingestão de nitritos o esôfago de Barrett foi registrado em 26,3% (5/19, enquanto no grupo operado associado à ingestão de nitritos, foi encontrado em 72,3% (13/18 dos animais, sendo que neste grupo também foi encontrado seis adenocarcinomas (33,3%. Nenhum animal não operado apresentou o esôfago de Barrett. As categorias 2, 3 e 5 da classificação de Viena somente foram encontradas nos animais operados que ingeriram nitrito de sódio (66,7%. CONCLUSÃO: A ingestão de nitrito de sódio associado ao refluxo duodenogastroesofágico têm importante participação na gênese do adenocarcinoma associado ao esôfago de Barrett.BACKGROUND: Barrett's esophagus is a complication of gastroesophageal reflux and predisposes to adenocarcinoma of the esophagogastric transition and several factors have been related to its pathogenesis. AIM: To evaluated the genesis of adenocarcinoma associated with Barrett's esophagus in an

  14. S- and Sr-isotopic compositions in barite-silica chimney from the Franklin Seamount, Woodlark Basin, Papua New Guinea: constraints on genesis and temporal variability of hydrothermal fluid

    Science.gov (United States)

    Ray, Durbar; Banerjee, Ranadip; Balakrishnan, S.; Paropkari, Anil L.; Mukhopadhyay, Subir

    2017-07-01

    Isotopic ratios of strontium and sulfur in six layers across a horizontal section of a hydrothermal barite-silica chimney from Franklin Seamount of western Woodlark Basin have been investigated. Sr-isotopic ratios in barite samples (87Sr/86Sr = 0.70478-0.70493) are less radiogenic than seawater (87Sr/86Sr = 0.70917) indicating that substantial leaching of sub-seafloor magma was involved in the genesis of hydrothermal fluid. The SO2 of magma likely contributed a considerable amount of lighter S-isotope in fluid and responsible for the formation of barite, which is isotopically lighter (δ34S = 19.4-20.5 ‰) than modern seawater (δ34S 21 ‰). The systematic changes in isotopic compositions across the chimney wall suggest temporal changes in the mode of mineral formation during the growth of the chimney. Enrichment of heavy S- and Sr-isotopes (δ34S = 20.58 ‰; 87Sr/86Sr = 0.70493) in the outermost periphery of the chimney indicates that, at the initial stage of chimney development, there was a significant contribution of seawater sulfate during barite mineralization. Thereafter, thickening of chimney wall occurred due to precipitation of fluid carrying more magmatic components relative to seawater. This led to a gradual enrichment of lighter isotopes (δ34S = 20.42-19.48 ‰; 87Sr/86Sr = 0.70491-0.704787) toward the inner portion of the chimney wall. In contrast, the innermost layer surrounding the fluid conduit is characterized by heavier and more radiogenic isotopes (δ34S = 20.3 ‰; 87Sr/86Sr = 0.7049). This suggests there was increasing influence of percolating seawater on the mineral paragenesis at the waning phase of the chimney development.

  15. Flux and genesis of CO2 degassing from volcanic-geothermal fields of Gulu-Yadong rift in the Lhasa terrane, South Tibet: Constraints on characteristics of deep carbon cycle in the India-Asia continent subduction zone

    Science.gov (United States)

    Zhang, Lihong; Guo, Zhengfu; Sano, Yuji; Zhang, Maoliang; Sun, Yutao; Cheng, Zhihui; Yang, Tsanyao Frank

    2017-11-01

    Gulu-Yadong rift (GYR) is the longest extensional, NE-SW-trending rift in the Himalayas and Lhasa terrane of South Tibet. Many volcanic-geothermal fields (VGFs), which comprise intense hot springs, steaming fissures, geysers and soil micro-seepage, are distributed in the GYR, making it ideal area for studying deep carbon emissions in the India-Asia continent subduction zone. As for the northern segment of GYR in the Lhasa terrane, its total flux and genesis of CO2 emissions are poorly understood. Following accumulation chamber method, soil CO2 flux survey has been carried out in VGFs (i.e., Jidaguo, Ningzhong, Sanglai, Tuoma and Yuzhai from south to north) of the northern segment of GYR. Total soil CO2 output of the northern GYR is about 1.50 × 107 t a-1, which is attributed to biogenic and volcanic-geothermal source. Geochemical characteristics of the volcanic-geothermal gases (including CO2 and He) of the northern GYR indicate their significant mantle-derived affinities. Combined with previous petrogeochemical and geophysical data, our He-C isotope modeling calculation results show that (1) excess mantle-derived 3He reflects degassing of volatiles related with partial melts from enriched mantle wedge induced by northward subduction of the Indian lithosphere, and (2) the crust-mantle interaction can provide continuous heat and materials for the overlying volcanic-geothermal system, in which magma-derived volatiles are inferred to experience significant crustal contamination during their migration to the surface.

  16. Using the chemical analysis of magnetite to constrain various stages in the formation and genesis of the Kiruna-type chadormalu magnetite-apatite deposit, Bafq district, Central Iran

    Science.gov (United States)

    Heidarian, Hassan; Lentz, David; Alirezaei, Saeed; Peighambari, Sima; Hall, Douglas

    2016-12-01

    Textural and compositional data are presented for different types of magnetite in the Chadormalu iron deposit to discern the genesis of various styles of mineralization. Samples were chosen according to their paragenetic relations to apatite and their host setting: magnetite-apatite veins in the altered host rocks, disseminated magnetite-apatite assemblages in the marginal parts of the main ore body, and massive magnetite associated with irregular apatite veinlets from internal part of the main ore body. Scanning electron microscopy - back scatter electron (SEM-BSE) images reveal that there are three main generations of magnetite in each of the different magnetite-apatite assemblages. Primary magnetite (Mag1) features abundant porosity and a dark appearance. A second generation of magnetite (Mag2) replacing Mag1 shows a lighter appearance with both sharp and gradational contacts with the primary magnetite crystals. The two magnetite types are related to dissolution-precipitation processes due to changing physico-chemical parameters of the ore fluids. A third type of magnetite (Mag3) with a recrystallized appearance and foam-like triple junctions was mostly observed in magnetite-apatite veins in the main ore body and in veins hosted by altered rocks. Electron probe microanalyses (EPMA) were utilized to discriminate the various magnetite generations in the different magnetite-apatite assemblages. Applying published elemental discrimination diagrams shows that most primary magnetites fall into the hydrothermal- and Kiruna-type fields. Primary magnetite contains lower FeO (88.77-93.65 wt.%; average 91.5 wt.%), and higher SiO2 (0.21-2.26 wt.%; ave. 0.32 wt.%), Al2O3 (0.001-0.45 wt.%; ave. 0.053 wt.%), and CaO (0.002-0.48 wt.%; ave. 0.078 wt.%) contents, which might be related to magmatically derived fluids. Secondary magnetites have higher FeO (89.23-93.49 wt.%; ave. 92.11 wt.%), lower SiO2 (0.037-0.189 wt.%; ave. 0.072 wt.%), Al2O3 (0.004-0.072 wt.%; ave. 0.019 wt

  17. Zircon U-Pb ages and Sr-Nd-Hf isotopes of the highly fractionated granite with tetrad REE patterns in the Shamai tungsten deposit in eastern Inner Mongolia, China: Implications for the timing of mineralization and ore genesis

    Science.gov (United States)

    Jiang, Si-Hong; Bagas, Leon; Hu, Peng; Han, Ning; Chen, Chun-Liang; Liu, Yuan; Kang, Huan

    2016-09-01

    The Shamai tungsten deposit is located in the eastern part of the Central Asian Orogenic Belt (CAOB). Tungsten mineralization is closely related to the emplacement of fine- to medium-grained biotite monzogranite (G1) and porphyritic biotite monzogranite (G2) in the Shamai Granite. NW-trending joints and faults host orebodies in the Shamai Granite and Devonian hornfels. The mineralization is characterized by a basal veinlet zone progressing upwards to a thick vein zone followed by a mixed zone, a veinlet zone, and a thread vein zone at the top. The ore-related alteration typically consists of muscovite, greisen, and hornfels. In order to constrain the timing of the Shamai mineralization and discuss the ore genesis, muscovite Ar-Ar, molybdenite Re-Os, and zircon U-Pb geochronological, geochemical, and Sr-Nd-Hf isotopic studies were completed on the deposit. The U-Pb zircon dating yielded weighted mean ages of 153 ± 1 Ma for G1 and 146 ± 1 Ma for G2. Muscovite from a wolframite-bearing quartz vein yielded an Ar-Ar plateau age of 140 ± 1 Ma, whereas two molybdenite samples yielded identical Re-Os model ages of 137 ± 2 Ma. These two ages are younger than the two monzogranites, suggesting a prolonged magmatic-hydrothermal interaction during tungsten mineralization. Major and trace element geochemistry shows that both G1 and G2 are characterized by high SiO2 and K2O contents, high A/CNK values (1.08-1.40), a spectacular tetrad effect in their REE distribution patterns, and non-CHARAC (charge-and-radius-controlled) trace element behavior. This suggests that both G1 and G2 are highly differentiated peraluminous rocks with strong hydrothermal interaction. The Nd-Hf isotope data for the Shamai Granite (εNd(t) between - 1.9 and + 7.4, ɛHf(t) from 5.2 to 12.8) are largely compatible with the general scenario for much of the Phanerozoic granite emplaced in the CAOB. It is here suggested that the Shamai Granite originated from partial melting of a juvenile lower crust with

  18. In-situ U-Pb, Hf and Re-Os isotopic analyses of the Xiangshan Ni-Cu-Co deposit in Eastern Tianshan (Xinjiang), Central Asia Orogenic Belt: Constraints on the timing and genesis of the mineralization

    Science.gov (United States)

    Han, Chunming; Xiao, Wenjiao; Zhao, Guochun; Ao, Songjian; Zhang, Jien; Qu, Wenjun; Du, Andao

    2010-12-01

    The timing and genesis of the major Ni-Cu-Co sulfide deposit in the Xiangshan intrusion have been studied based on newly obtained in-situ U-Pb, Hf and Re-Os isotopic analyses. The SIMS U-Pb zircon ages of the gabbro hosting the Ni-Cu-Co sulfide deposit indicate that the Xiangshan intrusion was emplaced at 279.6 ± 1.1 Ma (95% confidence level, MSWD = 1.30, n = 15). On the basis of combined geological and geochronological evidence, we suggest that the Xiangshan and other adjacent Ni-Cu deposits were formed in the same period. Sulphides have low common Os concentrations and high Re/Os ratios, similar to sulphide ores from the Duluth, Sally Malay and Voisey Bay complexes. The Re-Os isotopic data from the disseminated and massive ores from the Xiangshan intrusion do not form a single isochron, as they have different initial Os ratios. The Hf and Os isotopic data suggest that the Xiangshan intrusion and associated Ni-Cu-Co mineralization were derived from crustally contaminated mantle melts. The geochemical data show a tholeiitic affinity and a strong suprasubduction zone signature with negative Nb, Sr, and Ti anomalies similar to N-MORB and E-MORB. We suggest that the mafic-ultramafic rocks and associated Ni-Cu mineralization of the Eastern Tianshan orogen formed in an Alaska-type subduction zone-arc setting. Some diagnostic features of ridge-trench interaction are present in the Chinese East Tianshan orogen (e.g. granites, adakites, high-Mg andesites, near-trench magmatism, Alaskan-type mafic-ultramafic complexes, high-temperature metamorphic belts that prograde rapidly from low-grade belts, and orogenic gold deposits). The above distinctive rock groups are probably related to the same thermal event, ridge subduction, as in the Cenozoic orogen of Alaska. We suggest that ridge subduction is the most plausible mechanism to provide the necessary heat. Ridge subduction provides an important promising model for understanding many aspects of the evolution of the Chinese

  19. Genesis and Evolution of Digital Payment Platforms

    DEFF Research Database (Denmark)

    Hjelholt, Morten; Damsgaard, Jan

    2012-01-01

    Payment transactions through the use of physical coins, bank notes or credit cards have for centuries been the standard formats of exchanging money. Recently online and mobile digital payment platforms has entered the stage as contenders to this position and possibly could penetrate societies...... thoroughly and substitute current payment standards in the decades to come. This paper portrays how digital payment paltforms evolve in socio-technical niches and how various technological platforms aim for institutional attention in their attempt to challenge earlier platforms and standards. The paper...... applies a co-evolutionary multilevel perspective to model the interplay and processes between technology and society wherein digital payment platforms potentially will substitute other payment platforms just like the credit card negated the check. On this basis this paper formulate a multilevel conceptual...

  20. Angiography in tumors of cartilaginous genesis

    International Nuclear Information System (INIS)

    Korolev, V.I.

    1986-01-01

    Angiography was used for 122 patients with tumors and tumor-like processes of the cartilage. Angiography was carried out by the S. Seldinger method. Normal angioarchitecture was observed in 16 patients with benign tumors (20 patients), characters of malignant tumor are determined in 4 patients. Normal angioarchitecture is determined in 9.4% of patients with chondrosarcoma (102 patients). The examination carried out showed that angiographic symptotics in chondrosarcomas varied depending on the stage, localization and the degree of morphologic differentiation

  1. Genesis of tornadoes associated with hurricanes

    Science.gov (United States)

    Gentry, R. C.

    1983-01-01

    The climatological history of hurricane-tornadoes is brought up to date through 1982. Most of the tornadoes either form near the center of the hurricane, from the outer edge of the eyewall outward, or in an area between north and east-southeast of the hurricane center. The blackbody temperatures of the cloud tops which were analyzed for several hurricane-tornadoes that formed in the years 1974, 1975, and 1979, did not furnish strong precursor signals of tornado formation, but followed one of two patterns: either the temperatures were very low, or the tornado formed in areas of strong temperature gradients. Tornadoes with tropical cyclones most frequently occur at 1200-1800 LST, and although most are relatively weak, they can reach the F3 intensity level. Most form in association with the outer rainbands of the hurricane.

  2. Genesis of the Lunar Landing Vehicle

    Science.gov (United States)

    Gelzer, Christian

    2009-01-01

    The author examines early research regarding return flight from a Moon landing made prior to President Kennedy's 1961 challenge to put men on the Moon before the end of the decade. Organizations involved in early research include NACA, the Flight Research Center (now Dryden) Bell Aircraft Corporation. The discussion focuses on development of a flight simulator to model the Moon's reduced gravity and development of the Lunar Landing Research Vehicle.

  3. Identifying Genes Involved in Paraganglioma Genesis

    NARCIS (Netherlands)

    J. Gaal (José)

    2010-01-01

    textabstractThe paraganglion system is composed of a collection of chromaffin cells that is distributed throughout the body. Embryonically, chromaffin cells arise from the neuroectodermal tissue of the neural crest and are thought to migrate along the innervating nerves or vasculature towards

  4. Genesis and maintenance of "Mediterranean hurricanes"

    Directory of Open Access Journals (Sweden)

    K. Emanuel

    2005-01-01

    Full Text Available Cyclonic storms that closely resemble tropical cyclones in satellite images occasionally form over the Mediterranean Sea. Synoptic and mesoscale analyses of such storms show small, warm-core structure and surface winds sometimes exceeding 25ms-1 over small areas. These analyses, together with numerical simulations, reveal that in their mature stages, such storms intensify and are maintained by a feedback between surface enthalpy fluxes and wind, and as such are isomorphic with tropical cyclones. In this paper, I demonstrate that a cold, upper low over the Mediterranean can produce strong cyclogenesis in an axisymmetric model, thereby showing that baroclinic instability is not necessary during the mature stages of Mediterranean hurricanes.

  5. Ensemble Prediction of Tropical Cyclone Genesis

    Science.gov (United States)

    2017-02-23

    5f. WORK UNIT NUMBER 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) I PRCISOEST, University of Hawaii at Manoa 1680 East - West Road, POST...Tim Li IPRC/SOEST, University of Hawaii at Manoa 1680 East - West Road, POST Building 409B Honolulu, Hawaii 96822 Phone: (808) 956-9427, fax: (808... environment with a near bottom vortex or an environment with a mid- level vortex. Five experiments were designed with different initial vertical vorticity and

  6. Genesis of ZnO nanoparticles

    International Nuclear Information System (INIS)

    Silva, M.N. da; Pulcinelli, S.H.; Santilli, C.V.

    2014-01-01

    Zinc oxide is a semiconductor with direct band gap, of 3,37 eV, and high excitons energy (60 MeV). The main key for comprehension of the mechanisms that rules particle formation, lay in a full understanding of the first step of formation and growing of this nanoparticle. Zinc oxide nanoparticle were prepared through modification in the method first proposed by Spanhel & Anderson, the characterization techniques were followed by UV-Vis spectroscopy and small angle X ray scattering (SAXS). The results have shown that in the reaction first step we have nanoparticle size between 0,32 e 2,0 nm, whose growing steps can be described by Diffusion-limited cluster-cluster aggregation (DLCA), where self-similar primary structures aggregate keeping the initial morphology. (author)

  7. Genesis of dwarf galaxies in interacting system

    International Nuclear Information System (INIS)

    Duc, Pierre-Alain

    1995-01-01

    This research thesis addresses the study of interacting and merging galaxies, and more particularly the associated stellar formation episodes. The author first reports an analysis of the central regions of these objects by studying a specific class among them, i.e. galaxies discovered by the IRAS satellite which are ultra-luminous in the far infrared. The author presents results obtained by optical and infrared imagery and spectroscopy of a complete sample of objects located in the southern hemisphere. In the second part, the author focusses on outside regions of interacting galaxies, discusses the observation of filaments formed under the influence of tidal forces acting during galactic collisions, and of condensations which are as luminous as dwarf galaxies. Then a multi-wavelength study of several neighbouring systems revealed the existence of a specific class of objects, the tidal dwarf galaxies, which are formed from stellar and gaseous material snatched from the disk of interacting galaxies. Gas-rich tidal dwarf galaxies contain, like dwarf irregular galaxies or blue compact galaxies, newly formed stars. But, in opposition with these ones, they are richer in heavy elements: this is one of the consequences of a specific mode of galactic formation based on a cosmic recycling [fr

  8. The genesis of public health ethics.

    Science.gov (United States)

    Bayer, Ronald; Fairchild, Amy L

    2004-11-01

    As bioethics emerged in the 1960s and 1970s and began to have enormous impacts on the practice of medicine and research--fuelled, by broad socio-political changes that gave rise to the struggles of women, African Americans, gay men and lesbians, and the antiauthoritarianism impulse that characterised the New Left in democratic capitalist societies--little attention was given to the question of the ethics of public health. This was all the more striking since the core values and practices of public health, often entailing the subordination of the individual for the common good, seemed opposed to the ideological impulses of bioethics. Of what relevance is autonomy-focused bioethics for public health, with its mix of justifications including those that are either implicitly or explicitly paternalistic or that seek to impose strictures on individuals and communities in the name of collective welfare? To examine the deep divide between the central commitments of bioethics and the values that animate the practice of public health, we focus on a series of controversies implicating the concepts of privacy, liberty, and paternalism. Recognising the role of moral values in decision-making was a signal contribution of bioethics in its formative period. Over the past three decades a broad array of perspectives emerged under the rubric of bioethics but individualism remains central. As we commence the process of shaping an ethics of public health, it is clear that bioethics is the wrong place to start when thinking about the balances required in defence of the public's health.

  9. Historical genesis of Hanford Site wastes

    International Nuclear Information System (INIS)

    Gerber, M.S.

    1991-01-01

    This paper acquaints the audience with historical waste practices and policies as they changed over the years at the Hanford Site, and with the generation of the major waste streams of concern in Hanford Site clean-up today. The paper also describes the founding and basic operating history of the Hanford Site, including World War 11 construction and operations, three major postwar expansions (1947-55), the peak years of production (1956-63), production phase downs (1964-the present), and some past suggestions and efforts to chemically treat, open-quotes fractionate,close quotes and/or immobilize Hanford's wastes. Recent events, including the designation of the Hanford Site as the open-quotes flagshipclose quotes of Department of Energy (DOE) waste remediation efforts and the signing of the landmark Hanford Federal Facility Agreement and Consent Order (Tri-Party Agreement), have generated new interest in Hanford's history. Clean-up milestones dictated in this agreement demand information about how, when, in what quantities and mixtures, and under what conditions, Hanford Site wastes were generated and released. This paper presents original, primary-source research into the waste history of the Hanford Site. The earliest, 1940s knowledge base, assumptions and calculations about radioactive and chemical discharges, as discussed in the memos, correspondence and reports of the original Hanford Site (then Hanford Engineer Works) builders and operators, are reviewed. The growth of knowledge, research efforts, and subsequent changes in Site waste disposal policies and practices are traced. Finally, the paper places the current Hanford Site waste remediation endeavors in the broad context of American and world history

  10. T Cell Genesis: In Vitro Veritas Est?

    OpenAIRE

    Brauer, Patrick M.; Singh, Jastaranpreet; Xhiku, Sintia; Zúñiga-Pflücker, Juan Carlos

    2016-01-01

    T cells, as orchestrators of the adaptive immune response, serve important physiological and potentially therapeutic roles, for example in cancer immunotherapy. T cells are readily isolated from patients; however, the yield of antigen-specific T cells is limited, thus making their clinical use challenging. Therefore, the generation of T lymphocytes from hematopoietic stem/progenitor cells (HSPCs) and human pluripotent stem cells (PSCs) in vitro provides an attractive method for large-scale pr...

  11. Bourgeois Revolution: The Genesis of a Concept

    DEFF Research Database (Denmark)

    Nygaard, Bertel

    2006-01-01

    The concept ‘bourgeois revolution' developed through a particular synthesis of three world views, each with its own period of dominance in Western thought. In the enlightenment views of civilization history developing in Scotland and France from the 1740's till about 1800, materialist notions...

  12. The Genesis 2.0 Project

    CERN Multimedia

    Andersen, Kurt

    2010-01-01

    "Compared with the market-driven, killer-app insta-culture of the Digital Age, the new Large Hadron Collider exists in a near-magical realm, a $9 billion cathedral of science that is apparently, in any practical sense, useless. Exploring its whizbang machinery, deep underground, Kurt Andersen probes the collider's brush with disaster last year - and the secrets it may soon unlock" (10 pages)

  13. Anoxic environments and oil source bed genesis

    Energy Technology Data Exchange (ETDEWEB)

    Demaison, G J [Chevron Overseas Petroleum Inc., San Francisco, CA; Moore, G T

    1980-01-01

    The anoxic, aquatic, environment is a mass of water so depleted in oxygen that virtually all aerobic biological activity has ceased. Anoxic conditions occur where the demand for oxygen in the water column exceeds the supply. The specific cause for preferential lipid enrichment probably relates to the biochemistry of anaerobic bacterial activity. Recent evidence suggests that ancient organic-rich sediments containing hydrogen-rich kerogens (potential oil source beds) were deposited in similar anoxic environments. We propose the following classification for modern aquatic anoxic settings: (1) Large anoxic lakes - Permanent stratification promotes development of anoxic bottom water, particularly in large, deep lakes, which are not subject to seasonal overturn, e.g., Lake Tanganyika. (2) Anoxic silled basins - Landlocked silled basins with positive water balance tend to become anoxic. Typical are the Baltic and Black Seas. In arid region seas (Red and Mediterranean Seas), evaporation exceeds river inflow, causing negative water balance and well-aerated, nutrient-depleted bottom waters. (3) Anoxic layers caused by upwelling - Develop only when the oxygen supply in deep water cannot match demand by decaying organisms. Examples are the Benguela current and Peru coastal upwelling. (4) Open ocean anoxic layers - Found at intermediate depths in the northeastern Pacific and northern Indian Oceans; due to distance from deep, oxygenated polar water sources. Analogous to world-wide anoxic events at times of global climatic warm-ups and major transgressions, as in late Jurassic and middle Cretaceous time. Petroleum exploration can be greatly assisted by using geochemistry to identify paleo-anoxic events in the stratigraphic record. Recognition of the proposed anoxic models in ancient sedimentary basins should help in regional mapping of oil shales and oil-source beds. 17 figures.

  14. Genesis of Electroweak Unification and the Higgs

    CERN Multimedia

    CERN. Geneva

    2014-01-01

    I will give a historical account of the developments leading up to the unification of weak and electromagnetic interactions, as I saw them from my standpoint in Imperial College London. I will describe the state of physics in the 1950s, the aim of finding a unified theory of various interactions, the obstacles encountered in trying to unify the weak and electromagnetic interactions, and their eventual resolution, with a brief discussion of the later history culminating in the discovery of the Higgs boson in 2012.

  15. Genesis of uranium-gold pyritic conglomerates

    International Nuclear Information System (INIS)

    Myers, W.B.

    1981-01-01

    The ancient pyritic ore conglomerates have a common origin best exemplified by the Witwatersrand deposits. All contain detrital pyrite and uraninite, which are unstable in modern oxygenated environments and were deposited in a reducing atmosphere. The Rand reefs are not similar to modern gold placers. Placers result from the near incapacity of streams and currents to transport coarse gold. Placers as rich as Rand reef occur only in narrow paystreaks within 15 kilometers of a coarse-gold source. The board dispersion of gold in the reefs is due to solution transport of metal complexed as aurous sulfide, leached anoxygenically from crustal rocks, probably from sea-floor basalt, and precipitated by a slow reaction driven by the radioactive decay of detrital uraninite. Radiolysis of water on shallow marine unconformities resulted in diffusion of hydrogen to the atmosphere and a slight excess of hydroxyl free radical in the reef environment. The mild oxidizing tendency slowly dissolved uranium, precipitated gold, and oxygenated thucholite. These actions define a maturing process. A uraninite placer accumulating on an unconformity becomes progressively converted to a gold reef with little residual uraninite. The most mature reefs tend to grade toward the thucholite-seam type, very thin but exceedingly rich in gold. A combination of chemical attack and physical reworking accounts for the general thinness of mature reefs. Pyrite, like uraninite, decreases in abundance with increasing maturity; buffering by pyrite moderated the oxidative depletion of uranium. Where pyrite was scanty or absent, uraninite was completely dissolved by the effects of radiolysis and no ore formed

  16. The mammalian ovary from genesis to revelation.

    Science.gov (United States)

    Edson, Mark A; Nagaraja, Ankur K; Matzuk, Martin M

    2009-10-01

    Two major functions of the mammalian ovary are the production of germ cells (oocytes), which allow continuation of the species, and the generation of bioactive molecules, primarily steroids (mainly estrogens and progestins) and peptide growth factors, which are critical for ovarian function, regulation of the hypothalamic-pituitary-ovarian axis, and development of secondary sex characteristics. The female germline is created during embryogenesis when the precursors of primordial germ cells differentiate from somatic lineages of the embryo and take a unique route to reach the urogenital ridge. This undifferentiated gonad will differentiate along a female pathway, and the newly formed oocytes will proliferate and subsequently enter meiosis. At this point, the oocyte has two alternative fates: die, a common destiny of millions of oocytes, or be fertilized, a fate of at most approximately 100 oocytes, depending on the species. At every step from germline development and ovary formation to oogenesis and ovarian development and differentiation, there are coordinated interactions of hundreds of proteins and small RNAs. These studies have helped reproductive biologists to understand not only the normal functioning of the ovary but also the pathophysiology and genetics of diseases such as infertility and ovarian cancer. Over the last two decades, parallel progress has been made in the assisted reproductive technology clinic including better hormonal preparations, prenatal genetic testing, and optimal oocyte and embryo analysis and cryopreservation. Clearly, we have learned much about the mammalian ovary and manipulating its most important cargo, the oocyte, since the birth of Louise Brown over 30 yr ago.

  17. The genesis of adiabatic shear bands

    Czech Academy of Sciences Publication Activity Database

    Landau, P.; Osovski, S.; Venkert, A.; Gärtnerová, Viera; Rittel, D.

    2016-01-01

    Roč. 6, Nov (2016), s. 1-6, č. článku 37226. ISSN 2045-2322 R&D Projects: GA ČR GBP108/12/G043 Institutional support: RVO:68378271 Keywords : mechanical engineering * mechanical properties * metals and alloys * phase transitions and critical phenomena Subject RIV: BM - Solid Matter Physics ; Magnetism OBOR OECD: Condensed matter physics (including formerly solid state physics, supercond.) Impact factor: 4.259, year: 2016

  18. The genesis of errors in drawing.

    Science.gov (United States)

    Chamberlain, Rebecca; Wagemans, Johan

    2016-06-01

    The difficulty adults find in drawing objects or scenes from real life is puzzling, assuming that there are few gross individual differences in the phenomenology of visual scenes and in fine motor control in the neurologically healthy population. A review of research concerning the perceptual, motoric and memorial correlates of drawing ability was conducted in order to understand why most adults err when trying to produce faithful representations of objects and scenes. The findings reveal that accurate perception of the subject and of the drawing is at the heart of drawing proficiency, although not to the extent that drawing skill elicits fundamental changes in visual perception. Instead, the decisive role of representational decisions reveals the importance of appropriate segmentation of the visual scene and of the influence of pictorial schemas. This leads to the conclusion that domain-specific, flexible, top-down control of visual attention plays a critical role in development of skill in visual art and may also be a window into creative thinking. Copyright © 2016 Elsevier Ltd. All rights reserved.

  19. The genesis of the golden age

    DEFF Research Database (Denmark)

    Dalgaard, Carl Johan; Strulik, Holger

    2017-01-01

    We develop a life cycle model featuring an optimal retirement decision in the presence of physiological aging. In modeling the aging process we draw on recent advances within the fields of biology and medicine. In the model individuals decide on optimal consumption during life, the age...... of retirement, and (via health investments) the timing of their death. Accordingly, “years in retirement” is fully endogenously determined. Using the model we can account for the evolution of age of retirement and longevity across cohorts born between 1850 and 1940 in the US. Our analysis indicates that 2....../3 of the observed increase in longevity can be accounted for by wage growth, whereas the driver behind the observed rising age of retirement appears to have been technological change in health care. Both technology and income contribute to the rise in years in retirement, but the contribution from income...

  20. Forms and genesis of species abundance distributions

    Directory of Open Access Journals (Sweden)

    Evans O. Ochiaga

    2015-12-01

    Full Text Available Species abundance distribution (SAD is one of the most important metrics in community ecology. SAD curves take a hollow or hyperbolic shape in a histogram plot with many rare species and only a few common species. In general, the shape of SAD is largely log-normally distributed, although the mechanism behind this particular SAD shape still remains elusive. Here, we aim to review four major parametric forms of SAD and three contending mechanisms that could potentially explain this highly skewed form of SAD. The parametric forms reviewed here include log series, negative binomial, lognormal and geometric distributions. The mechanisms reviewed here include the maximum entropy theory of ecology, neutral theory and the theory of proportionate effect.

  1. Genesis of Preeclampsia: An Epidemiological Approach

    Science.gov (United States)

    Salvador-Moysén, Jaime; Martínez-López, Yolanda; Ramírez-Aranda, José M.; Aguilar-Durán, Marisela; Terrones-González, Alberto

    2012-01-01

    There are analyzed some of the main aspects related to the causality of preeclampsia, privileging two types of models: the clinic model and the epidemiologic model, first one represented by the hypothesis of the reduced placental perfusion and the second one considering the epidemiologic findings related to the high levels of psychosocial stress and its association with preeclampsia. It is reasoned out the relevance of raising the causality of the disease from an interdisciplinary perspective, integrating the valuable information generated from both types, clinical and epidemiologic, and finally a tentative explanatory model of preeclampsia is proposed, the subclinical and sociocultural aspects that predispose and trigger the disease are emphasized making aspects to stand out: the importance of reduced placental perfusion as an indicator of individual risk, and the high levels of physiological stress, as a result of the unfavorable conditions of the psychosocial surroundings (indicator of population risk) of the pregnant women. PMID:22462008

  2. The Bioeconomy: Genesis and Modern Imperatives

    Directory of Open Access Journals (Sweden)

    Kravchuk Nataliia І.

    2018-02-01

    Full Text Available The history of origin, the essence, properties, and driving forces of the bioeconomy are disclosed. Three approaches to its interpretation are synthesized: technological, resource, and ecological. The foreign experience of implementation of the bioeconomy in economic activity of different branches is generalized. The place of the bioeconomy in development strategy of the leading world countries: USA, Germany, Finland, France, Great Britain, Italy, and participation in this process of the international organizations are researched. It is determined that the bioeconomic system should become a component of the national economy of the country. The socio-economic activity, based on the processes that have a biological basis, promotes: sustainable and efficient solution of problems in the food, chemical, forest industries, mechanical engineering, energy, health protection; formation of food security; preservation of ecological-economic equilibrium. The system of the following determinants of the bioeconomy: stability, entropy, renewal, symbiosis, unorthodoxness, dynamic efficiency has been proposed. The dynamic efficiency is part of a new perspective concept of the circular economics.

  3. The genesis of unified gauge theories

    International Nuclear Information System (INIS)

    Kibble, Tom

    1993-01-01

    The theoretical physics group at London's Imperial College in 1959 had three permanent faculty: Abdus Salam, his erstwhile thesis supervisor Paul Matthews, and John C.Taylor. I joined as a lecturer the following year. In those early days we had lots of visitors, both long- and short-term - Murray Gell-Mann, Ken Johnson, John Ward, Lowell Brown, Gordon Feldman and Steven Weinberg. About a year after I arrived we were transferred from the Mathematics to the Physics Department under the formidable Patrick (P.M.S.) Blackett. Having been brought up in the Cavendish Laboratory tradition under Lord Rutherford, Blackett was rather scornful of theoretical physicists, but he knew a good thing when he saw one and had persuaded Salam to join the rapidly expanding Physics Department. In 1960 field theory was widely regarded as very passé. It had had its triumphs: renormalization theory had made sense of divergences, and quantum electrodynamics had been magnificently vindicated. But field theory didn't seem to work for anything else, particularly not for the strong interactions, and was definitely out of fashion. There were, however, a few places in the world where field theory was still studied unashamedly. Imperial College was one. Harvard was certainly another; many of our visitors over the next few years were Julian Schwinger's students

  4. Reactive transport and the genesis of kimberlites

    DEFF Research Database (Denmark)

    Pilbeam, Llewellyn; Nielsen, Troels; Waight, Tod Earle

    was short magmatic temperatures of ~900oC were supported. ! [1] Nielsen & Sand (2008), Canadian Mineralogist 46, 1043- 1061 [2] Ardnt, Guitreau, Boullier, Le Roex, Tommasi, Cordier & Sobolev (2010), Journal of Petrology 51, 573-602 [3] Mitchell (2008), Journal of Volcanology and Geothermal Research 174, 1...

  5. Genesis of Business Tourism in the World

    Directory of Open Access Journals (Sweden)

    Тamara E. Rastegaeva

    2012-05-01

    Full Text Available There are many elements of activities of people which fall under category of business travel in each historical era. Forming of the modern market of the international business meetings occurred in the sixties the XX century when international associations claimed congresses, conferences. Today, business travel became an integral part of modern production process.

  6. Plasma: the genesis of the word

    OpenAIRE

    Pinheiro, Mario J.

    2007-01-01

    The historical roots of the word plasma are recalled. It is suggested that possibly at the beginning of the researches in low-pressure gas discharges the driving motivation was related to the psychic phenomena investigated by Sir William Crookes.

  7. CORRUPTION IN SOUTH AFRICA: GENESIS AND OUTLOOK

    Directory of Open Access Journals (Sweden)

    Natasha Georgieva Hadji Krsteski

    2017-10-01

    Full Text Available Corruption in South Africa includes the private use of public resources, bribery and improper favouritism. South Africa scored 45 points out of 100 on the 2016 Corruption Perceptions Index reported by Transparency International. Corruption Index in South Africa averaged 46.97 Points from 1996 until 2016, reaching an all-time high of 56.80 Points in 1996 and a record low of 41 Points in 2011. A tenderpreneur is common corruption in South Africa. It is an individual who enriches themselves through corrupting the awarding of government tender contracts, mostly based on personal connections and corrupt relationships - although outright bribery might also take place - and sometimes involving an elected or politically appointed official (or his or her family members holding simultaneous business interests. This is often accompanied by overcharging and shoddy workmanship. BEE-fronting is an abuse of the rules governing Black Economic Empowerment (BEE, where qualifying persons are given a seat on the Board of Directors of a company while having no decision-making power in the company, in order to qualify the company for government contracts in terms of BEE.

  8. The genesis of surficial uranium deposits

    International Nuclear Information System (INIS)

    Boyle, D.R.

    1984-01-01

    Surficial uranium deposits can form in such diverse environments as calcareous-dolomitic-gypsiferous fluvial and aeolian valley sediments in hot arid and semi-arid regions, oxidizing and reducing alkaline and saline playas, highly organic and/or clay-rich wetland areas, calcareous regoliths in arid terranes, laterites, lake sediments, and highly fractured zones in igneous and metamorphic basement complexes. Formation of ore is governed by the interrelationships between source of ore-forming elements, mechanisms of migration, environment of deposition, climate, preservation, tectonic history and structural framework. The principal factors controlling mobilization of ore-forming elements from source to site of deposition are the availability of elements in source rocks, presence of complexing agents, climate, nature of source rock regolith and structure of source rock terrane. The major processes governing precipitation of uranium in the surficial environment are reduction mechanisms, sorption processes, dissociation of uranyl complexes, change in redox states of ore-forming constituents, evaporation of surface and groundwaters, change in partial pressure of dissolved carbon dioxide, changes in pH, colloidal precipitation, and mixing of two or more surface and groundwaters. One or a number of these processes may be actively involved in ore formation. (author)

  9. Digital Genesis: Computers, Evolution and Artificial Life

    OpenAIRE

    Taylor, Tim; Dorin, Alan; Korb, Kevin

    2015-01-01

    The application of evolution in the digital realm, with the goal of creating artificial intelligence and artificial life, has a history as long as that of the digital computer itself. We illustrate the intertwined history of these ideas, starting with the early theoretical work of John von Neumann and the pioneering experimental work of Nils Aall Barricelli. We argue that evolutionary thinking and artificial life will continue to play an integral role in the future development of the digital ...

  10. The genesis of unified gauge theories

    Energy Technology Data Exchange (ETDEWEB)

    Kibble, Tom

    1993-06-15

    The theoretical physics group at London's Imperial College in 1959 had three permanent faculty: Abdus Salam, his erstwhile thesis supervisor Paul Matthews, and John C.Taylor. I joined as a lecturer the following year. In those early days we had lots of visitors, both long- and short-term - Murray Gell-Mann, Ken Johnson, John Ward, Lowell Brown, Gordon Feldman and Steven Weinberg. About a year after I arrived we were transferred from the Mathematics to the Physics Department under the formidable Patrick (P.M.S.) Blackett. Having been brought up in the Cavendish Laboratory tradition under Lord Rutherford, Blackett was rather scornful of theoretical physicists, but he knew a good thing when he saw one and had persuaded Salam to join the rapidly expanding Physics Department. In 1960 field theory was widely regarded as very passé. It had had its triumphs: renormalization theory had made sense of divergences, and quantum electrodynamics had been magnificently vindicated. But field theory didn't seem to work for anything else, particularly not for the strong interactions, and was definitely out of fashion. There were, however, a few places in the world where field theory was still studied unashamedly. Imperial College was one. Harvard was certainly another; many of our visitors over the next few years were Julian Schwinger's students.

  11. Black hole genesis of dark matter

    Science.gov (United States)

    Lennon, Olivier; March-Russell, John; Petrossian-Byrne, Rudin; Tillim, Hannah

    2018-04-01

    We present a purely gravitational infra-red-calculable production mechanism for dark matter (DM) . The source of both the DM relic abundance and the hot Standard Model (SM) plasma is a primordial density of micro black holes (BHs), which evaporate via Hawking emission into both the dark and SM sectors. The mechanism has four qualitatively different regimes depending upon whether the BH evaporation is 'fast' or 'slow' relative to the initial Hubble rate, and whether the mass of the DM particle is 'light' or 'heavy' compared to the initial BH temperature. For each of these regimes we calculate the DM yield, Y, as a function of the initial state and DM mass and spin. In the 'slow' regime Y depends on only the initial BH mass over a wide range of initial conditions, including scenarios where the BHs are a small fraction of the initial energy density. The DM is produced with a highly non-thermal energy spectrum, leading in the 'light' DM mass regime (~260 eV and above depending on DM spin) to a strong constraint from free-streaming, but also possible observational signatures in structure formation in the spin 3/2 and 2 cases. The 'heavy' regime (~1.2 × 108 GeV to MPl depending on spin) is free of these constraints and provides new possibilities for DM detection. In all cases there is a dark radiation component predicted.

  12. Galactic distribution and genesis of pulsars

    International Nuclear Information System (INIS)

    Guseinov, O.H.; Kasumov, F.K.

    1981-01-01

    The radial distribution of pulsars in the Galaxy have been calculated by the authors using the available electron density figure for each pulsar. Also the luminosity function, the evolution of luminosity with age and the birth rate were determined. (Auth.)

  13. The Genesis of August 2017 Nepal Floods

    Science.gov (United States)

    Uprety, M.; Dugar, S.; Gautam, D.; Budimir, M.; Parajuli, B.; Kharbuja, R. G.

    2017-12-01

    The 2017 monsoon in Nepal was normal until mid-August 2017 when a low pressure system that formed parallel to the foothills of the Churia range brought significant amount of rain in the southern Terai belt. Rivers from East to West swelled as many of them crossed the pre-defined warning thresholds, and rainfall depths in excess of 200 mm to 600 mm were recorded in over a dozen meteorological stations across the country between 11th and 13th of August. The West Rapti River recorded water level of approximately 9 meters while the adjacent Babai River crossed 10 meters and smaller rivers such as Riu Khola and Kankai rose up to 4.8 meters and 5.5 meters respectively, well above danger levels for consecutive days. Early warning systems established in the aforementioned rivers were critical to saving lives and livelihoods. However the severity of flash floods from intermittent streams that originate from the Churia range caught people unaware and led to massive water logging and devastation across Eastern and Central Nepal that claimed 96 lives and displaced more than 14.060 families. The Department of Hydrology and Meteorology with help from telecom operators sent more than 6 million SMS messages to communities residing along the floodplains. These messages provided them with critical information on when to evacuate their homes and move to safer grounds, yet the shear spatial scale and extend of floods meant that communities struggled to find refuge on higher ground. Whilst the Global Flood Awareness System (GLoFAS) indicated with medium probability that major rivers across Nepal might swell in mid-August and the 3 day rainfall forecasts from the Numerical Weather Prediction (NWP) consistently indicated heavy precipitation in the southern Terai belt, yet no significant early actions were taken in response to this information. Despite the availability of forecast information on streamflow prediction and rainfall, there was limited pre-emptive actions and now it is imperative that governments, donors and humanitarian responders in Nepal think beyond the traditional disaster response and relief paradigm and move towards developing and investing in a system that links scientific weather forecasts with predefined early preparedness actions which is currently being piloted and can contribute towards minimizing disaster losses.

  14. Genesis and kinetics of peritoneal macrophages

    International Nuclear Information System (INIS)

    Wacker, H.H.

    1982-01-01

    The author intended to develop an experimental model for investigations of the proliferation kinetics of tissue macrophages, using the example of peritoneal macrophages. To get a suitable cell population, a blood cell population was labelled with 3 H-thymidine and transferred in a parabiotic test. (orig./MG) [de

  15. Aspects of the Genesis of Linear Perspective

    DEFF Research Database (Denmark)

    Laursen, Bjørn

    This article is a contribution to the study of how sighted and blind people perceive and draw cubes. For many years the author has taught sighted people perspective drawing and published books in Scandinavia about drawing. His point of departure in this article is pointing out typical obstacles s...... of psychology John M. Kennedy, that blind people intuitively and rapidly seem to invent perspective drawing, a phenomenon sighted people in The Middle Ages used more than a hundred years to develop.......This article is a contribution to the study of how sighted and blind people perceive and draw cubes. For many years the author has taught sighted people perspective drawing and published books in Scandinavia about drawing. His point of departure in this article is pointing out typical obstacles...... sighted people run into seeing and drawing linear perspective. Blind people’s conditions for drawing a cube are presented and compared with the ones sighted people meet. The overall aim of this article is to contribute pedagogically and theoretically to explain a basic paradox, pointed out by professor...

  16. Genesis of non-codified customs

    Directory of Open Access Journals (Sweden)

    Atefeh Roohi Kargar

    2017-12-01

    Full Text Available The study of what is called “customary law” and “non-written rules” is always faced with ambiguity due to the lack of written resources. The reason for emphasizing the role of custom and applying the words on their customary meanings was to re-focus on this rich source of rights, which is far from sights. By reviewing the Articles, books and documentary data, we tried to look again at the status of unwritten conventions, legal rules and legal principles that could be interpreted as legal norms. If written or assigned to a bunch or a material to them, along with other laws they can be a good complement. This paper intends to review the role of custom and habit in concluding contracts by reviewing past comparative law studies and helping out the role of custom and unwritten rights. Besides, it intends to unify the material of Arts. 220, 225 and other Arts. of civil law of the parties to the awareness of the custom, because ignorance of the customary is not like ignorance of the law.

  17. Genesis and classification of Oxisols in a highland toposequence of the upper Jequitinhonha Valley (MG Gênese e classificação de Latossolos em topossequência das chapadas do alto Vale do Jequitinhonha (MG

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    Celmo Aparecido Ferreira

    2010-02-01

    Full Text Available The Brazilian System of Soil Classification (SiBCS is a taxonomic system, open and in permanent construction, as new knowledge on Brazilian soils is obtained. The objective of this study was to characterize the chemical, physical, morphological, micro-morphological and mineralogical properties of four pedons of Oxisols in a highland toposequence in the upper Jequitinhonha Valley, emphasizing aspects of their genesis, classification and landscape development. The pedons occupy the following slope positions: summit - Red Oxisol (LV, mid slope (upper third - Yellow-Red Oxisol (LVA, lower slope (middle third- Yellow Oxisol (LA and bottom of the valley (lowest third - "Gray Oxisol" ("LAC". These pedons were described and sampled for characterization in chemical and physical routine analyses. The total Fe, Al and Mn contents were determined by sulfuric attack and the Fe, Al and Mn oxides in dithionite-citrate-bicarbonate and oxalate extraction. The mineralogy of silicate clays was identified by X ray diffraction and the Fe oxides were detected by differential X ray diffraction. Total Ti, Ga and Zr contents were determined by X ray fluorescence spectrometry. The "LAC" is gray-colored and contains significant fragments of structure units in the form of a dense paste, characteristic of a gleysoil, in the horizons A and BA. All pedons are very clayey, dystrophic and have low contents of available P and a pH of around 5. The soil color was related to the Fe oxide content, which decreased along the slope. The decrease of crystalline and low- crystalline Fe along the slope confirmed the loss of Fe from the "LAC". Total Si increased along the slope and total Al remained constant. The clay fraction in all pedons was dominated by kaolinite and gibbsite. Hematite and goethite were identified in LV, low-intensity hematite and goethite in LVA, goethite in LA. In the "LAC", no hematite peaks and goethite were detected by differential X ray diffraction. The micro

  18. Study on the uranium mineralization genesis of the Cachoeira, Lagoa Real, Bahia, mine, as auxiliary in the discovery and comprehension of mineral beds; Estudo da genese da mineralizacao uranifica da mina da Cachoeira, Lagoa Real, BA, como auxilio na descoberta e compreensao de jazidas minerais

    Energy Technology Data Exchange (ETDEWEB)

    Oliveira, Lucilia Aparecida Ramos de; Rios, Francisco Javier; Chaves, Alexandre de Oliveira; Pereira, Ana Rosa Passos [Centro de Desenvolvimento da Tecnologia Nuclear (CDTN/CNEN-MG), Belo Horizonte, MG (Brazil)]. E-mail: laro@cdtn.br

    2007-07-01

    The acknowledgement of the geological history of a ore reserve allows to infer relative to a large area with possibility to contain the large mineral content or even give the localization of new anomalies or mineral reserve. The study of ore reserve genesis is of great importance for the stages to obtain the mineral, from the prospection until the mineral mining. Fluid inclusions (FI) are fluid quantities which are imprison in the minerals during the formation process or some process where deformation occurs. The study of fluid inclusions, together with the petrographic mapping of the blades associated to the uranium para genesis of Lagoa Real, Brazil, are been used for a better comprehension of the uranium orogenesis. The main analysis techniques used in this context were the petrography and microthermometry. With the petrographic analysis fluid inclusions were observed and mapped in various minerals present in rocks associated to uranium mineralization, such as amphiboles, pyroxenes and grenades. The micro thermometric studies were only performed in the pyroxenes and the grenades due to the fluid inclusions types found in these minerals, and also the supposed relationships that those minerals have with uranium mineralization at that region. (author)

  19. Molecular nuclear imaging of tumoral angio genesis using a rgd-containing tracer, Raft-RGD, targeted at the neo vessel-specific integrin {alpha}{sub v}{beta}{sub 3}; Evaluation d'un radioligand de l'integrine {alpha}{sub v}{beta}{sub 3} (RAFT-RGD) pour l'imagerie moleculaire de l'angiogenese tumorale

    Energy Technology Data Exchange (ETDEWEB)

    Sancey, L

    2006-06-15

    Tumoral neo-angio genesis targeting is currently a major field of research for the diagnostic and treatment of solid tumors. Endothelial cells from neo vessels over express several specific markers such as the {alpha}{sub v}{beta}{sub 3} integrin, which binds RGD (-Arg-Gly-Asp-)- containing peptides. We evaluated the potential of a novel radiotracer - RAFT-RGD - for the molecular nuclear imaging of neo vessels. In vitro, the coupling of 4 c(RGDfK) to the RAFT platform resulted in an increased cellular uptake of the tracer by {alpha}{sub v}{beta}{sub 3} positive cells when compared to c(RGDfK). Furthermore, RAFTRGD has a higher affinity than c(RGDfK) and similar properties for angio genesis inhibition. In vivo, both {alpha}{sub v}{beta}{sub 3} positive and negative tumors were visible by non invasive whole body planar and tomographic imaging from 30 min to 24 h post-injection, using a gamma camera dedicated to small animal imaging. Despite a lack of significant contrast improvement compare with c(RGDfK), RAFT-RGD could represent a promising tracer for tumoral angio genesis since it could provide invaluable information about tumor development and treatment efficacy in Nuclear Medicine departments. Furthermore, thanks to its chemical structure, RAFT-RGD can be labelled with a variety of radioisotopes including {gamma} and {beta}{sup -} emitters, allowing interesting therapeutical applications such as internal targeted radiotherapy. (author)

  20. Gênese, desenvolvimento, crise e reformas nos serviços públicos de extensão rural durante a década de 1990 Genesis, development, crisis and reforms in public agricultural extension during the 1990s

    Directory of Open Access Journals (Sweden)

    César Augusto Da Ros

    2012-01-01

    Full Text Available Este artigo traça um painel histórico sobre a gênese, desenvolvimento, crise e reformas realizadas nos serviços públicos de extensão rural ao longo da década de 1990, oferecendo uma visão geral sobre os seus principais determinantes, tendo por base a literatura especializada sobre o tema. Neste percurso, analisou-se o processo de constituição dos aparatos institucionais destinados ao oferecimento dos serviços de extensão rural e sua vinculação as políticas de modernização técnica da agropecuária mundial durante o período do pós-guerra, tecendo-se considerações sobre o caso brasileiro. O artigo também examina os aspectos que determinaram na emergência de uma crise dos serviços públicos de extensão rural ocorrida ao longo da década de 1980, num contexto de intensificação das críticas ao modelo agrícola da revolução verde. Por fim, o artigo busca destacar as conexões existentes entre a crise e as reformas de privatização dos serviços públicos de extensão rural ocorridas em diversos países do mundo durante a década de 1990 pautadas na reformulação dos seus formatos institucionais, das formas de financiamento, dos seus objetivos, do seu público alvo, das metodologias de trabalho e da matriz tecnológica preconizadaThis article presents an historical overview of the processes of genesis, development, crisis and reforms in public agricultural extension throughout the 1990s, offering an overview of its main determinants, based on the literature on the subject. In this way, we analyzed the process of constitution of institutional apparatuses for the offering of extension services and linking policies technical modernization of agriculture worldwide during the postwar period, weaving considerations on the Brazilian case. The article also examines the aspects that determined the emergence of a crisis of public extension occurred during the 1980s, amid intensifying criticism of the Green Revolution model of

  1. Gênese de horizonte coeso, fragipã e duripã em solos do tabuleiro costeiro do sul da Bahia Genesis of hardened horizons, fragipan and duripan in soils of the coastal tablelands of south Bahia

    Directory of Open Access Journals (Sweden)

    Ana Maria Souza dos Santos Moreau

    2006-12-01

    Full Text Available A gênese de horizontes coesos em solos tem explicações não consistentes e, em muitos casos, contraditórias. Objetivou-se avaliar, em solos dos tabuleiros costeiros, os possíveis mecanismos físicos, químicos e mineralógicos que ocasionam o endurecimento em horizonte coeso, fragipã e duripã. Para isso, coletaram-se amostras de solos em duas toposseqüências. Na primeira, foram reconhecidas as classes Latossolo Vermelho eutrófico argissólico e Argissolo Amarelo distrófico latossólico e, na segunda, Argissolos Amarelo abrúptico e típico, e Espodossolo Cárbico órtico dúrico. As análises químicas consistiram da extração de Fe, Si e Al com ditionito-citrato-bicarbonato de sódio e oxalato ácido de amônio. A mineralogia da fração argila foi avaliada por difratometria de raios-X. Os teores de Fe, Si e Al recuperados com o ditionito e com o oxalato foram bastante baixos nos solos com presença de horizonte coeso. Por outro lado, no solo com fragipã e duripã, os teores de Si e Al do oxalato foram elevados, indicando a participação desses elementos como agentes cimentantes. A fração argila dos Argissolos é predominantemente caulinítica, sendo registrada a gibbsita apenas nos horizontes Bt1, Bt2 e Bw do Argissolo Amarelo latossólico. Para o solo com fragipã e duripã (Espodossolo Cárbico órtico dúrico, identificou-se a presença de gibbsita, e, apesar de ser a gibbsita considerada como desorganizadora do ajuste entre as lâminas de caulinita, a manifestação de endurecimento foi mantida. Assim, os mecanismos de endurecimento parecem distintos para horizonte coeso, fragipã e duripã.The genesis of cohesive horizons in some soils is not well known yet and, in many cases, it is conflicting. The purpose of this study was to evaluate physical, chemical and mineralogical mechanisms that cause hardening in soils with cohesive horizons, fragipan and duripan in Brazilian Coastal Plain soils. Soil samples of two

  2. A escola de Belas Artes de Pelotas: aspectos de sua gênese e constituição - The escola de Belas Artes de Pelotas: aspects of its genesis and constitution

    Directory of Open Access Journals (Sweden)

    Clarice Rego Magalhães, Giana Lange do Amaral

    2011-03-01

    Full Text Available Resumo Este trabalho aborda a gênese e constituição de uma instituição de ensino de arte: a Escola de Belas Artes de Pelotas (EBA. O objetivo do estudo é esclarecer quais foram as condições que possibilitaram a criação da EBA em março de 1949. A constituição desta narrativa histórica tem por base fontes escritas, formadas pelos  arquivos  da própria instituição, pelo arquivo particular da família da fundadora da Escola, por periódicos locais e  por  trechos do diário da fundadora, além  de fontes  orais.  Pela análise das fontes,  concluímos que o nascimento da EBA se deu por uma conjunção de  fatores, os quais seriam a vocação cultural da cidade, oriunda da sua história peculiar, e  a  atuação  de   personalidades que,  naquele  momento,   fizeram acontecer o fato histórico. Palavras-chave: Escola de Belas Artes; instituição de  ensino  de arte; história da educação; história das instituições escolares.   THE ESCOLA DE BELAS ARTES DE PELOTAS: ASPECTS  OF ITS GENESIS AND CONSTITUTION Abstract This work examines the genesis and constitution of an art teaching institution: the Escola de Belas Artes de Pelotas (EBA. The purpose of this study is to elucidate the  conditions which made possible the creation of EBA in March, 1949.  This historic account is based on written   sources,  namely  the   institution’s   archives,  the   school founder’s  family private archives, local journals  and  exerts from the founder’s diary, besides oral sources. The analysis of the sources led us to conclude that  the  birth  of EBA  occurred as the  result of a conjunction  of  factors  which are  the  town’s  cultural  inclination, derived from its peculiar history, and the actions of some individuals that, at that moment, made the historic fact happen. Keywords: Fine Arts School; art teaching institution; history of education; teaching institutions history.   LA

  3. Gênese de solos derivados de rochas ultramáficas serpentinizadas no sudoeste de Minas Gerais Genesis of soils formed from ultramafic serpentinized rocks in southwestern Minas Gerais (Brazil

    Directory of Open Access Journals (Sweden)

    Pablo Vidal-Torrado

    2006-06-01

    presença de minerais primários de fácil decomposição até mesmo na fração argila, com destaque para o talco, clorita trioctaedral e ocorrência limitada de tremolita, sendo esta última abundante na fração silte. Óxidos de Fe, caulinita e os interestratificados de clorita-esmectita e de clorita-vermiculita completam a assembléia mineralógica. A tendência de evolução é para B textural ou para B nítico com mineralogia 1:1 e alto conteúdo de óxidos de Fe. Nas fases iniciais de alteração, os alteromorfos já apresentam composição química similar aos agregados do solo, com forte perda de Mg, Ca e Si e acúmulo relativo de Al e Fe. Nas três situações estudadas, ocorreu um rejuvenescimento superficial por erosão diferencial, que acumulou material grosseiro e removeu os finos, contribuindo para o incremento da relação textural.Soils formed from serpentinized rocks or serpentinites constitute a special group of soils on the earth surface. These rocks present ultramafic characteristics, with more than 70 % mafic minerals (iron and magnesium oxides. The mineralogy of serpentinites is poor in silica and aluminum and very rich in Mg. Only few studies have looked into the morphology, mineralogy, genesis and classification of soils developed on this type of parent material. In the humid-tropical climate of southwestern Minas Gerais state, three representative soil profiles were taken from the Morro do Ferro, in the Greenstone Belt area, on young geomorphic surfaces. They were characterized by macro and micromorphological descriptions, particle size distribution and chemical analysis, and X ray mineralogical analysis of the clay and sand fractions. The geochemical alterations in the soil horizons were characterized by EDRX microanalyses of soil thin sections. The soils were classified as Haplic Phaeozern Eutric Regosol and chromic Cambisol. Although these soils are developed in a climate that favors quick weathering, from a morphological and mineralogical

  4. Genesis of B lymphocytes in the bone marrow: extravascular and intravascular localization of surface IgM-bearing cells in mouse bone marrow detected by electron-microscope radioautography after in vivo perfusion of 125I anti-IgM antibody

    International Nuclear Information System (INIS)

    Osmond, D.G.; Batten, S.J.

    1984-01-01

    The role of mammalian bone marrow in generating surface IgM (sIgM)-bearing B lymphocytes is reviewed. Precursor cells in the marrow give rise to large, rapidly dividing cells bearing free cytoplasmic mu chains (c mu). The progeny of the large c mu+ cells form a population of small, nondividing c mu+ cells that mature into small lymphocytes, progressively expressing sIgM and other B-cell surface membrane components. Newly formed sIgM+ cells soon migrate through the bloodstream to the spleen and other lymphoid tissues, where they may die after a short lifespan or be activated to produce antibody molecules. The large-scale lymphocytopoiesis in the bone marrow thus maintains a population of rapidly renewed virgin B lymphocytes in the peripheral lymphoid tissues. A technique for perfusing radiolabeled anti-IgM antibodies in young mice has now permitted sIgM+ cells to be detected radioautographically in histological preparations of bone marrow under the electron microscope. Small sIgM+ lymphocytes are situated either singly or in small groups throughout the extravascular hemopoietic compartment of the bone marrow, often near sinusoid walls adjacent to late erythroblasts and reticular cells. Some regional concentrations of sIgM+ cells are apparent. sIgM+ cells also appear in transit through the sinusoidal endothelium and are markedly concentrated in the lumen of some sinusoids. Intrasinusoidal sIgM+ small lymphocytes have high densities of sIgM and long microvilli, on which sIgM molecules are concentrated. These studies reveal the localization and cell associations of specifically identified sIgM+ small lymphocytes in the extravascular marrow compartment and suggest that these cells may also undergo a transient intravascular storage and maturation phase. Use of this in vivo immunolabeling technique to detect other cell-surface markers may further elucidate the microenvironmental basis of B lymphocyte genesis in the bone marrow

  5. Soils of The Irkutsk Region, Agriculture Land Funds and Quality Of Soils. Chapter 3. Development of Genesis, Geography and Agrochemical Properties of Soils Studies at Experimental Stations, Higher Education Institutions and Scientific Research Institutions of Irkutsk (in the 20s-80s of XX Century.

    Directory of Open Access Journals (Sweden)

    V.T. Kolesnichenko

    2017-08-01

    Full Text Available In this monograph, based on many years of research by the author, systematization and generalization of soil and cartographic materials of the Siberian Institute of the Siberian Branch of the Russian Academy of Sciences, as well as the use of a large number of literary and fund sources, the characteristics of soil formation and soil cover in the Irkutsk region are given. It is shown that, due to the great extent of the territory of the region from north to south and from west to east, the heterogeneity of the relief, geological structure, climatic conditions and vegetation, the soil cover is characterized by a complex structure and a wide variety of soil types. Based on the latest research and modern ideas on the genesis of soils, a systematic description of the soils and their diagnostics is given, specific features of the temperature and water regimes of seasonally frozen soils, the structure of the soil profile, physical and chemical properties are reported, which inform the regional features of the soils forming here, determining the fertility of soils and Ways of their rational use in agricultural production. A new scheme for soil-geographical zoning of the territory of the Irkutsk region was developed, which was used as the basis for the soil map of the Irkutsk region at a scale of 1:1 500 000, published by the USSR in 1988. Areas of soil zones, sub-zones and districts were determined and the degree of their agricultural use was indicated. The calculations of the areas of the main types of soils along the soil zones, subareas and districts used in agriculture are given. The data contained in the monograph make it possible to assess the potential for further agricultural development of soils both in the southern regions of the region and in the north – in areas of new industrial construction and in the zone of the western section of the BAM. The work can serve as an explanatory note to the soil map of the Irkutsk region at a scale of 1: 1

  6. The genesis of the base metal ore deposit from Herja

    Directory of Open Access Journals (Sweden)

    Gheorghe Damian

    2003-04-01

    Full Text Available The Herja ore deposit is one of the most known of the Baia Mare Neogene metallogenetic district and is associated with a complex stock of Pannonian age. The hydrothermal alterations associated with the mineralizations are represented by: the propylitization, the argillization, the phyllic and potassic alteration. The monoascenedant character of the mineralizations is predominant. The magmatic intrusions have been sequential placed and have represented the heat, metals and hydrothermal solutions source. In the first stages of mineralization the hydrothermal solutions contain predominantly magmatic water and in the final stages the water is of connate and meteoric origin. According to the structural magmatic control, to the mineralogical composition and to the hydrothermal alterations, the Herja ore deposits are of a low sulphidation epithermal systems type.

  7. Genesis, visual attributes and contemporary communication features of the alphabet

    Directory of Open Access Journals (Sweden)

    Filip Cvitić

    2014-10-01

    Full Text Available Throughout 5,000 years of human literacy, the alphabet system has developed from pictograms and ideograms to the contemporary system of Latin letters. The simplification of primary pictograms and their transformation to ideograms followed the major goal of written communication – to transmit thoughts and ideas. Besides, written communication has enabled preservation of knowledge, and that has generated the expansion of information and its availability today. The high speed of gathering written information, as well as its superabundance, calls for rethinking of semiotic features of Latin letters as the basic units of written communication in the Western world, especially in terms of marketing communication and its effectiveness. The written expression is the major tool of branding and getting closer to target market segments. Social development influences the development of communication, which is visible through numerous brands and signs, i.e. symbols that make products and companies recognizable in the market. The distinct sign forms of the alphabet are used to suggest the story of a brand, product or service. A constituent element of its comprehension is conscious or unconscious knowledge drawn from different sources in the environment. The history of human literacy, the development of each particular letter, the communication rules of the contemporary marketplace, the impact of brands and information superabundance make up the basis for further research into communication features of the alphabet, semantics of written forms and their redefinition in the context of effective marketing communication.

  8. Genesis of magnetic fields in isolated white dwarfs

    Science.gov (United States)

    Briggs, Gordon P.; Ferrario, Lilia; Tout, Christopher A.; Wickramasinghe, Dayal T.

    2018-05-01

    A dynamo mechanism driven by differential rotation when stars merge has been proposed to explain the presence of strong fields in certain classes of magnetic stars. In the case of the high field magnetic white dwarfs (HFMWDs), the site of the differential rotation has been variously thought to be the common envelope, the hot outer regions of a merged degenerate core or an accretion disc formed by a tidally disrupted companion that is subsequently accreted by a degenerate core. We have shown previously that the observed incidence of magnetism and the mass distribution in HFMWDs are consistent with the hypothesis that they are the result of merging binaries during common envelope evolution. Here we calculate the magnetic field strengths generated by common envelope interactions for synthetic populations using a simple prescription for the generation of fields and find that the observed magnetic field distribution is also consistent with the stellar merging hypothesis. We use the Kolmogorov-Smirnov test to study the correlation between the calculated and the observed field strengths and find that it is consistent for low envelope ejection efficiency. We also suggest that field generation by the plunging of a giant gaseous planet on to a white dwarf may explain why magnetism among cool white dwarfs (including DZ white dwarfs) is higher than among hot white dwarfs. In this picture a super-Jupiter residing in the outer regions of the white dwarf's planetary system is perturbed into a highly eccentric orbit by a close stellar encounter and is later accreted by the white dwarf.

  9. Characterisation and genesis of the Singhbhum uranium province, India

    International Nuclear Information System (INIS)

    Mahadevan, T.M.

    1988-01-01

    The Singhbhum Uranium province is characterised by the late Archaean predominantly granitic Singhbhum Craton and the associated Proterozoic mobile belts, the boundaries of which are marked by major crustal dislocations. The Singhbhum craton had two-phase evolution during the time range 4000-2900 million years and its stabilisation around 2900 million years was marked by the emplacement of K-rich granitoids and the early crustal enrichment of uranium. Two distinctive types of uranium mineralisation occur in the Province - (i) the early Quartz Pebble Conglomerate (QPC) type and (ii) the later economically most significant shear-controlled hydrothermal type. The QPC type is confined to the cratonic volcano-sedimentary basins, characterised by basal fluvial high-energy deposits, near-continental volcanics and banded iron formations spanning the time band of 2900-2500 million years. The shear controlled hydrothermal mineralisation is predominantly developed in a 200 km-long arcuate zone of intense and deep tectonisation, acid-(?) alkaline-basic magmatism, hydrothermal activity and metallogenesis. This shear zone represents a belt of intense crust-mantle interaction. Uranium mineralisation is polyphasic, polymetallic. The mineralogy is complex and the chemistry of the ores is greatly influenced by the lithology of the host rocks involved in the shear. Part of the shear zone grazing the Dhanjori, predominantly volcanic supra-crustals is richer in U, Cu, Ni, Mo and also contains minor Bi, Au, Ag, Te and Se, while the western trans-Dhanjori sector of the shear zone characterised by schists and quartzites with lesser volcanic component is relatively poorer in these metals. The ore bodies in the trans-Dhanjori sector are more peneconcordant, gradational, stratabound and have spherical variograms, while those in the Dhanjori sector are transgressive, sharp, highly mobilised, vein type with Dewijsian variograms. A synthesis leads to the conclusion that uranium mineralisation is a result of a polycyclic mobilisation of uranium. 48 refs, 11 figs, 6 tabs

  10. Low dose irradiation facilitates hepatocellular carcinoma genesis involving HULC.

    Science.gov (United States)

    Li, Yuan; Ge, Chang; Feng, Guoxing; Xiao, Huiwen; Dong, Jiali; Zhu, Changchun; Jiang, Mian; Cui, Ming; Fan, Saijun

    2018-03-24

    Irradiation exposure positive correlates with tumor formation, such as breast cancer and lung cancer. However, whether low dose irradiation induces hepatocarcinogenesis and the underlying mechanism remain poorly defined. In the present study, we reported that low dose irradiation facilitated the proliferation of hepatocyte through up-regulating HULC in vitro and in vivo. Low dose irradiation exposure elevated HULC expression level in hepatocyte. Deletion of heightened HULC erased the cells growth accelerated following low dose irradiation exposure. CDKN1, the neighbor gene of HULC, was down-regulated by overexpression of HULC following low dose irradiation exposure via complementary base pairing, resulting in promoting cell cycle process. Thus, our findings provide new insights into the mechanism of low dose irradiation-induced hepatocarcinogenesis through HULC/CDKN1 signaling, and shed light on the potential risk of low dose irradiation for the development of hepatocellular carcinoma in pre-clinical settings. © 2018 Wiley Periodicals, Inc.

  11. Spin-down of radio millisecond pulsars at genesis.

    Science.gov (United States)

    Tauris, Thomas M

    2012-02-03

    Millisecond pulsars are old neutron stars that have been spun up to high rotational frequencies via accretion of mass from a binary companion star. An important issue for understanding the physics of the early spin evolution of millisecond pulsars is the impact of the expanding magnetosphere during the terminal stages of the mass-transfer process. Here, I report binary stellar evolution calculations that show that the braking torque acting on a neutron star, when the companion star decouples from its Roche lobe, is able to dissipate >50% of the rotational energy of the pulsar. This effect may explain the apparent difference in observed spin distributions between x-ray and radio millisecond pulsars and help account for the noticeable age discrepancy with their young white dwarf companions.

  12. The Okhansk Meteorite: Specifics of Composition, Structure, and Genesis

    Directory of Open Access Journals (Sweden)

    A.I. Bakhtin

    2016-12-01

    Full Text Available The Okhansk meteorite fell on August 18, 1887 near the village of Tabor, about 15 km away from the town of Okhansk in Perm province and weighed 186.5 kg (the total weight of collected fragments, according to P.I. Krotov, was more than 245 kg. The shock wave from the meteorite entry knocked down animals and riders on horses. Despite the fact that it was significantly stronger than that caused by the Chelyabinsk meteorite of 2013, all information about this meteorite has completely erased from people's memory. It has been shown that the meteorite is an ordinary olivine-bronzite chondrite. Its main silicate minerals are olivine, bronzite, plagioclase, and diopside. The main ore minerals are kamacite and troilite. The meteorite contains silicate glass in large amounts. The analysis of the composition and structure of the Okhansk meteorite has demonstrated that it was formed at the early stages of accretion of the melted substance of the protosolar nebula without undergoing endogenous, temperature, or pressure changes.

  13. J D Bernal and the genesis of structural biology

    Science.gov (United States)

    Caffrey, Martin

    2007-02-01

    I was invited to participate in this Symposium a month or so before the event. At that time however, I knew little about J D Bernal. I vaguely remembered a brief conversation on the topic over a decade ago with Professor Vittorio Luzzati as we ambled around the gardens at the Palace of Varsailles. Vittorio likely knew Bernal through his friend Rosalind Franklin who worked with Bernal at Birbeck College. But beyond that I knew nothing about the man or his science. And so it was most fortunate that Andrew Brown's book J D Bernal: The Sage of Science appeared in 2005 and I was able to call on it. Indeed, much of the material included in this chapter is based on that source and on Dorothy Hodgkin's biographic memoir of J D Bernal, her postgraduate supervisor. Given that this chapter is to be published in a Physics journal I thought it appropriate to provide some background to the theme of my presentation, structural biology. Accordingly, I will begin with an introduction to proteins, one of structural biology's central characters, and to which Bernal devoted much energy and attention. How the molecular structure of a protein determines its activity and function will then be described. Bernal's major contribution in this area was to X-ray crystallography, the primary method by which a protein's structure is determined. The method, and aspects of its development, will be described. I will also make reference to some of Bernal's additional contributions in related fields. Finally, Vincent Casey, the symposium organizer, asked that I comment on how structural biology might impact on society. I will attempt to address that at the close of my presentation.

  14. Analysis of GALE (Genesis of Atlantic Lows Experiment) Data

    Science.gov (United States)

    1989-12-01

    DIMENSION F(M,N) ,PHI(M,N) ,ERR(M,N) DIMENSION Fl1(M) ,FlN(M) ,F21(N) ,F2M(N) DIMENSION X(M) ,Y(N) ,YPI(N) ,YP2(N) DIMENSION HXU(N) ,HXV(N1) , HYU (N...DELY*DELY C DEFINE MAP FACTORS DO 10 J=1,N HXU(J)=COS(Y(J) /AR) HYU (J)=1.0 10 CONTINUE 31 DO 20J=1, NI. HXV(J)=O.5*(HXU(J)+HXU(J+1-)) 2HYV(J)=1.O...DIMENSION FllCH) ,FlN(M) ,F21(N) ,F2M(N) DIMENSION X(M) ,Y(N) ,YPi(N) ,YP2(N) DIMENSION--HXU(N) ,HXV(N1) , HYU .(N) ,HYV(Nl) DIMENSION AA(N) ,AC(N) ,CC(N

  15. Calcretes in the Thar desert: Genesis, chronology and ...

    Indian Academy of Sciences (India)

    R. Narasimhan (Krishtel eMaging) 1461 1996 Oct 15 13:05:22

    to Yaalon (1988) soils with secondary carbonate accumulations ..... The fraction over 500 µm constituted 6 to 8% of the sample and its absolute carbonate was less than 1%. .... However, if we take note of the uncertainty level of the estimate, an ...

  16. Genesis of Cenozoic intraplate high Mg# andesites in Northeast China

    Science.gov (United States)

    Liu, J. Q.; Chen, L. H.; Zhong, Y.; Wang, X. J.

    2017-12-01

    High-Mg# andesites (HMAs) are usually generated in the converged plate boundary and have genetic relationships with slab subduction. However, it still remained controversial about the origin of those HMAs erupted in the intra-plate setting. Here we present major, trace element, and Sr-Nd-Pb-Hf isotopic compositions for the Cenozoic intra-plate HMAs from Northeast China to constrain their origin and formation process. Cenozoic Xunke volcanic rocks are located in the northern Lesser Khingan Range, covering an area of about 3, 000 km2. These volcanic rocks are mainly basaltic andesite and basaltic trachyandesite, with only several classified as trachyandesite and andesites. They have high SiO2 contents (54.3-57.4 wt%) and Mg# (49.6-57.8), falling into the scope of high Mg# andesites. The Xunke HMAs are enriched in large ion lithophile elements but depleted in high field strength elements, with positive Ba, K, Sr and negative Zr-Hf, and Ti anomalies. Their trace element absolute concentrations are between those of potassic basalts and Wuchagou HMAs. The Xunke HMAs have relatively enriched Sr-Nd-Hf isotopes (87Sr/86Sr = 0.705398-0.705764, ɛNd=-8.8-3.8, ɛHf=0.5-11.7), and low radiogenic Pb isotopes (206Pb/204Pb = 16.701-17.198), towards to the EM1 end-member, which indicates that they are ultimately derived from ancient, recycled crustal components. Primitive silica-rich melts were generated from higher degrees of partial melting of recycled crustal materials (relative to potassic basalts) and then interacted with the peridotite to produce the Xunke HMAs.

  17. Historia Y Sociedad En La Genesis De Las Lenguas Criollas

    Directory of Open Access Journals (Sweden)

    Carlos Patino Rosselir

    2002-10-01

    Full Text Available This article delineates the historical process and the social conditions which gave birth to the variety of languages known as "Creóles" in Linguistics. The first part of the study places Creóles in the new domain called 'Language Contad', due to the multiethnic origin of these dialects. The second part deals with the African languages which came to the New World, the Euro-African contact vernaculars which emerged during the centuries of the slave trade, and the Communications network which obtained in colonial Cartagena. The final part sketches the 'life cycle' of Creoles and refers to R. Chaudenson's 'sociohistorical' approach.

  18. Sovereign debt threatens the Union: the genesis of a federation

    NARCIS (Netherlands)

    Loubert, A.

    2012-01-01

    Eurozone sovereign debt crisis - Europe's ‘Alexander Hamilton Moment’ - American sovereign debt crisis of 1780s - Articles of Confederation - U.S. Constitution - Assumption of states' debt - Constitutional transformation key factor in enabling Alexander Hamilton's debt restructuring.

  19. World Economic System: On the Genesis of a Concept

    Directory of Open Access Journals (Sweden)

    Theotonio dos Santos

    2015-08-01

    Full Text Available Political-economy has been generated during national economies and nation-state constitution; the theoretical effort that served as basis for the rise of economics as a science may be written within the boundaries of the analysis of national economies. This was, for example, Quesnay’s great contribution when establishing the economic-cycle concept by departing from the agricultural production and circulation process and going through the manufacturing and other “non-productive” activities. He disputed the mercantilist doctrines which saw wealth’s origin in trade, manufacturing, or gold or silver, according to their English, French or Spanish versions, respectively. The reaction Quesnay represented sought to show that wealth formation depended either on agricultural production, or on “productive labour”—what he called primary production—viewing circulation, trade, and the ?nancial sector as “unproductive” activities, dependent on productive labour.

  20. NATURAL BASES OF GENESIS OF UNTZUKUL ORNAMENTAL ART

    Directory of Open Access Journals (Sweden)

    G. G. GAZIMAGOMEDOV

    2010-01-01

    Full Text Available The work deals with Untzukul ornamental hatching wood by metal - it is the only phenomena in decoration applied art. Special attention is paid to succession of the traditions important for conservation and further development of the natural art trade of Daghestan republic.

  1. [Genesis and political background of "Sonderaktion Krakau" 6 XI 1939].

    Science.gov (United States)

    August, J

    1998-01-01

    The decision to imprison Cracow's University professors on November 6, 1939 was made in connection with the establishment of the so-called General Government, as a second stage of German security police action in nazi-occupied Poland to ensure German rule also over Central and Southern Poland. By this way Sonderaktion Krakau (Special Action Cracow)--as continuation of politische Flurbereinigung (political cleaning up) started in German occupied Western Poland in September 1939--was a part of a second wave of persecution directed against the Polish societies' social classes indicated by Nazi leaders and chiefs of German security police as Poland's leadership, a wave of persecution now, since the end of October 1939, enlarged on Central and Southern Poland. The imprisonment of the Cracow Professors subsequently marked the perspective, that Poland's scientific and academic institutions as a whole would be destroyed, so that in future no Polish scientists, intellectuals and university people even would have the possibility to do scientific work and to have subsistence from doing this kind of work. As a consequence, Poland's intellectuals and university-trained people as a social class in future would disappear indefinitely, and the people of Poland, deprived of intellectual leadership, would be transformed into a mass of dependend lower-class working people, so that the Nazi leaders mournfull future-scenario for their rule in German occupied Central and Eastern Europe would become reality. By this way the imprisonment of the Cracow Professors on November 6, 1939 was the first step to realize Nazi future plans concerning Central and Eastern Europe.

  2. Kosovo’s Crisis: Genesis of a Problem

    Science.gov (United States)

    2013-03-01

    1913 it attacked the Serbian forces. The Second Balkan War also involved Greece and Romania . For a short period, Bulgaria was defeated and it lost...formal declaration of war, attacked Serbia in June 1913, and the Second Balkan War began. Serbia, Montenegro, Romania , Greece and the Ottoman Empire...Serbian army was reorganized, and, after three months, it was sent to the Thessaloniki front. After a breakthrough at the front on September 14, 1918

  3. Hermeneutics in identity formation: Paul's use of Genesis in ...

    African Journals Online (AJOL)

    Test

    2010-08-06

    Aug 6, 2010 ... culture including religious belief, custom and ritual that provoked .... members of a group, rather than in their individual capacity. ... threefold taxonomy of his research (perceptual accentuation, ... The strong sense of identity in a collectivist or group- ..... invitation for identification whilst the ethical dimension.

  4. [Results of genesis and diagnosis of schizoid disorders].

    Science.gov (United States)

    Lieberz, K

    1991-01-01

    A group of 25 schizoid patients were compared with 76 neurotic patients and 103 healthy persons in terms of perceived parent imago and family dynamics. The following findings should be emphasized: 1. Schizoid persons can be distinguished well from other persons on the basis of their experience of family. 2. A clear delimitation of schizoid persons from neurotic persons is possible only when the factor of sex is considered. 3. Schizoid women differ from neurotic women in terms of their distinctive mother experience: The mothers of schizoid women are marked by a weak ego and are apprehensive and extremely permissive. 4. Schizoid men differ from neurotic men both in terms of a distinctive mother experience and a distinctive father experience. In their case, a negative mother imago is contrasted with an ambivalent father imago. Neurotic men, on the other hand, possess a mother imago nearly as positive as that of healthy men, although they do exhibit a distinctly more negative father imago. 5. Schizoid women differ from schizoid men in terms of a distinctively negative mother imago. Whereas the mothers of schizoid women are experienced above all as exhibiting a weak ego and traits of dependency, the mothers of schizoid men are perceived more as being strong and independent.

  5. The Genesis of Cyberscience and its Mathematical Models (CYBERSCIENCE)

    Science.gov (United States)

    2005-02-01

    October 1996. [Gas01] G. Gaskell. An Analysis of BS7799 and Requirements for eCommerce . In Proceedings of the 1st Symposium on Requirements Engineering for...identifying potential vulnerabilities in software. In 1998 IEEE Symposium 70 on Security and Privacy (SSP ’98), pages 104–114, Washington – Brussels...X. Qian, R. Riemenschneider, and L. Gong. Secure Software Architecture. In Proceedings of the 1997 IEEE Symposium on Security and Privacy , pages 84–93

  6. The Search for Genesis in the Castaway and Other Poems ...

    African Journals Online (AJOL)

    If In a Green Night Walcott grapples with isolated acts that coalesced into his delineation of the dilemma of his personality, in The Castaway and Other Poems, he attempts to situate the persona of In a Green Night in a landscape. To do this, Walcott creates a mythic history of the Caribbean personality by intertextually ...

  7. Joining Hands across the Seas: The Genesis of IASAS

    Science.gov (United States)

    Ludeman, Roger B.

    2014-01-01

    In this article, Roger Ludeman outlines the personal and organisational journey he took with many friends of student affairs and services around the world to envision and then create a new global professional association--the International Association of Student Affairs and Services (IASAS). During its 20 years of development, IASAS has come to…

  8. J D Bernal and the genesis of structural biology

    International Nuclear Information System (INIS)

    Caffrey, Martin

    2007-01-01

    I was invited to participate in this Symposium a month or so before the event. At that time however, I knew little about J D Bernal. I vaguely remembered a brief conversation on the topic over a decade ago with Professor Vittorio Luzzati as we ambled around the gardens at the Palace of Varsailles. Vittorio likely knew Bernal through his friend Rosalind Franklin who worked with Bernal at Birbeck College. But beyond that I knew nothing about the man or his science. And so it was most fortunate that Andrew Brown's book J D Bernal: The Sage of Science appeared in 2005 and I was able to call on it. Indeed, much of the material included in this chapter is based on that source and on Dorothy Hodgkin's biographic memoir of J D Bernal, her postgraduate supervisor. Given that this chapter is to be published in a Physics journal I thought it appropriate to provide some background to the theme of my presentation, structural biology. Accordingly, I will begin with an introduction to proteins, one of structural biology's central characters, and to which Bernal devoted much energy and attention. How the molecular structure of a protein determines its activity and function will then be described. Bernal's major contribution in this area was to X-ray crystallography, the primary method by which a protein's structure is determined. The method, and aspects of its development, will be described. I will also make reference to some of Bernal's additional contributions in related fields. Finally, Vincent Casey, the symposium organizer, asked that I comment on how structural biology might impact on society. I will attempt to address that at the close of my presentation

  9. Genesis of some tertiary Indian coals from the chemical composition ...

    Indian Academy of Sciences (India)

    Baruah. 2008) that in northeast Indian coals, the major minerals (wt% >5) identified in the crystalline matter of coal are quartz, kaolin, illite, feldspar, calcite, pyrite, and gypsum. Vassilev et al. (2010a, b) reported that the rank of the coal increases with.

  10. Geology and genesis of NORM industrial links and depositional processes

    International Nuclear Information System (INIS)

    Wilson, W.F.

    1995-01-01

    NORM (Naturally Occurring Radioactive Material) has now been found to be associated with many industrial activities that extends far beyond oil and gas production. There are approximately 59 naturally occurring radionuclides that might end up in a train of NORM contamination, which could impact at least 13 industries. It is appropriate and indeed necessary to examine the geological roots of NORM and its concentration in various industries. Impacted NORM industries and their associated problems are presented. Some plant and environmental managers may not even suspect they have NORM problems, because one cannot ''sense'' NORM without instrumentation, until it might be too late for the health and safety of the effected employees and surrounding community. Others want to ''see no evil, hear no evil or speak any evil'' until they are forced into ''reactive'' environmental management, rather than ''proactive'' management. It has been the experience of many that reactive management is far more costly than proactive management

  11. Inflammation in the genesis and perpetuation of atrial fibrillation

    DEFF Research Database (Denmark)

    Engelmann, Mads D M; Svendsen, Jesper Hastrup

    2005-01-01

    The prevalence and persistence of atrial fibrillation (AF) and the relative inefficacy of the currently available pharmacotherapy requires development of new treatment strategies. Recent findings have suggested a mechanistic link between inflammatory processes and the development of AF...

  12. Genesis of an Employee Wellness Program at a Large University.

    Science.gov (United States)

    Lloyd, Lisa K; Crixell, Sylvia H; Bezner, Janet R; Forester, Katherine; Swearingen, Carolyn

    2017-11-01

    University employee wellness programs have potential to support positive changes in employee health, thereby improving productivity and mitigating the rise in health care costs. The purpose of this article is to describe a theory-driven approach to systematically planning, developing, and implementing a comprehensive university employee wellness program. Long-term program goals were to improve employee health, well-being, and productivity by focusing on decreasing sedentary behavior, increasing physical activity, improving dietary habits, and reducing stress. An ecological approach was taken to identify levels of influence specific to a university setting: intrapersonal, interpersonal, department/college/division, and university. This framework guided the development of program components and strategies, which were grounded in several health behavior change theories. Input from supervisors and employees was incorporated throughout program development. A 15-week trial run, involving 514 employees, was evaluated to fine-tune services. Participation and feedback were positive, demonstrating that the program was valued. Support from upper administration is evidenced by continued funding. Critical factors to the successful launch of the program included a supportive administration, leverage of existing facilities and equipment, leadership provided by faculty, and service delivery by students.

  13. Nonlinear morphoelastic plates I: Genesis of residual stress

    KAUST Repository

    McMahon, J.

    2011-04-28

    Volumetric growth of an elastic body may give rise to residual stress. Here a rigorous analysis is given of the residual strains and stresses generated by growth in the axisymmetric Kirchhoff plate. Balance equations are derived via the Global Constraint Principle, growth is incorporated via a multiplicative decomposition of the deformation gradient, and the system is closed by a response function. The particular case of a compressible neo-Hookean material is analyzed, and the existence of residually stressed states is established. © SAGE Publications 2011.

  14. Genesis of scientific research of legal problems of reserves

    Directory of Open Access Journals (Sweden)

    Олександр Олександрович Пономаренко

    2017-12-01

    Full Text Available The problems of the legal status of nature reserves as objects of ecological and legal commandment are considered. One of the main directions of the modern strategy of Ukraine’s environmental policy should be the implementation of international standards in the organization and protection of nature reserves as objects of the state natural reserve fund, the improvement of legislation on the nature reserve fund in accordance with the recommendations of the Pan-European Biological and Landscape Diversity Strategy (1995 on the formation of the Pan-European Ecological Network as a single spatial system of territories of European countries with the EU or partially altered landscape. All this allowed to formulate the definition of a natural reserve as a state research institution with the status of a legal entity of national importance and performs the functions of preserving in a natural state typical or unique for the given landscape zone of natural complexes with all components of their components, the study of natural processes and phenomena, the developments in them, the development of scientific principles of environmental protection, the effective use of natural resources and environmental safety, the implementation of ecological education and education of the population in the conditions of full restriction of economic activity not connected with its functioning.

  15. Comparison of real development levels of countries: Genesis and perspectives

    Directory of Open Access Journals (Sweden)

    Prekajac Zora

    2007-01-01

    Full Text Available Comparison of levels of development among countries is usually done by reducing values in national currencies with a common denominator, using the official exchange rate. Because of its unreality, the values calculated in this way do not illustrate real relations between compared countries. That brings about the launching of the UN International Comparison Project (latter Programme with two fold aims: developing a method for international comparison of real domestic product which could be applied to a number of very heterogeneous countries, and the comparison of growing number of very different countries. Until now six phases of comparisons are finished. Taking into consideration problems that appeared in the realization of the VI ICP phase as well as quality improvement proposals, a decision has been made to launch a new, global round for 2003-2006. Comparison will cover 150 countries (the widest coverage ever. This will give global character to the comparison, which was the end cause of the ICP.

  16. Glycolytic overload and the genesis of breast cancer.

    Science.gov (United States)

    Robson, J R

    1984-03-01

    It is suggested that the development of breast cancer is due to overloading of the glycolytic pathways. An excess of substrates or an excessive delivery rate of substrates to the Krebs Cycle is believed to result in the formation of acetyl CoA. Feedback mechanisms controlling the conversion of acetyl CoA to cholesterol may be overcome; the resulting high concentration of cholesterol induces the formation of pregnenolone which may then be converted into androgens, estrogens and progesterone. These steroids are in addition to those produced by gonads and adrenal glands. Glycolytic overload is also associated with an increase in fat stores which have been shown to be the site of interconversion of sex hormones. Excess sex hormones or abnormal sex hormones are believed to be the cause of breast cancer. The hypothesis presented links glycolytic overload with clinical biochemical phenomena and explains some of the anomalies observed in breast cancer experience in different ethnic groups. Changes in dietary habits during the history of man resulting in " gorging " and the consumption of highly refined sugars are possible causes of glycolytic overload. So, also, is impaired thermogenesis due to Brown Fat deficits in certain ethnic groups.

  17. Instrumental Genesis in GeoGebra Based Board Game Design

    DEFF Research Database (Denmark)

    Misfeldt, Morten

    2013-01-01

    In this paper I address the use of digital tools (GeoGebra) in open ended design activities, with primary school children. I present results from the research and development project “Creative Digital Mathematics”, which aims to use the pupil’s development of mathematical board games as a vehicle...... in their work with GeoGebra and how they relate their work with GeoGebra and mathematics to fellow pupils and real life situations. The results show that pupils’ consider development of board games as meaningful mathematical activity, and that they develop skills with GeoGebra, furthermore the pupils considers...... potential use of their board game by classmates in their design activities....

  18. Bricks as indicators for an urban soil genesis

    Science.gov (United States)

    Nehls, Thomas; Rokia, Sarah; Schwartz, Christophe; Wessolek, Gerd

    2013-04-01

    Bricks can be considered as anthropogenic markers since they are regularly found in urban soils worldwide. They are among the most resistent residues of building materials, therefore are called technogenic substrates. They have been dumped to urban soils since more than 4000 years and can be dated back to their burning using thermoluminescence. In Berlin, bricks have been piled up to more than 37 rubble mountains in the city after WW II. The devils mountain, the most prominent of them is higher than 60m. However, bricks are known not to be isolated in the soil but to fulfill soil functions due to their porosity. Therefore, they are nice research objects for soil scientists. The purpose of this study is to investigate abundance and functions of bricks in urban soils, focusing on plant nutrition and contamination aspects. Three different Berlin urban soils have been studied for their brick contents in the coarse and fine earth fractions by endless hand sorting. Light and scanning electron microscopy was then employed to investigate the bricks for proofs of plant roots. Third, CEC, pH, EC, Corg, nutrient storage (XRF) and availability (2:1 extract, ion chromatography, AAS) of bricks and fine earth fractions of the corresponding soil horizons have been investigated. The fine earth fractions of the investigated soils contain 3 to 5% of bricks, while the coarse fractions contain up to 50%. We found roots entering brick pores or at least attached to brick surfaces. Therefore, plants can use the water and nutrients stored in bricks. The CEC of bricks is grain size dependent and reaches a maximum of 6 cmolc kg-1 for particles smaller than 0.063 mm. This dependency is not explained by a low pore connectivity. Rather, it is the result of the restricted diffusion into the brick pore system due to the short shaking time in the CEC analysis protocol. From the nutrient storage and availabilities we conclude that bricks can better supply plants with K, Mg, Ca and S than the bulk soil at the investigated sandy site. However, in general, the nutrient availability from bricks is rather low compared to agricultural soils, except for Ca and S. Because of the water and nutrient storage, low contamination status and the possible rooting of bricks, they can be used for amelioration of poor sandy soils and for soil construction.

  19. The Genesis of the 1986 National Policy on Education.

    Science.gov (United States)

    Ghosh, Suresh Chandra

    This paper discusses India's 1986 National Policy on Education and describes the policy's emphasis on the essential characteristics of a national educational system that provides opportunities for equal access to education irrespective of class, caste, creed, sex, or geographic location. The development of Indian education is featured, and the…

  20. Carbonatites in China: A review for genesis and mineralization

    Directory of Open Access Journals (Sweden)

    Cheng Xu

    2010-10-01

    Full Text Available Carbonatites are commonly related to the accumulation of economically valuable substances such as REE, Cu, and P. The debate over the origin of carbonatites and their relationship to associated silicate rocks has been ongoing for about 45 years. Worldwide, the rocks characteristically display more geochemical enrichments in Ba, Sr and REE than sedimentary carbonate rocks. However, carbonatite’s geochemical features are disputed because of secondary mineral effects. Rock-forming carbonates from carbonatites at Qinling, Panxi region, and Bayan Obo in China show REE distribution patterns ranging from LREE enrichment to flat patterns. They are characterized by a Sr content more than 10 times higher than that of secondary carbonates. The coarse- and fine-grained dolomites from Bayan Obo H8 dolomite marbles also show similar high Sr abundance, indicating that they are of igneous origin. Some carbonates in Chinese carbonatites show REE (especially HREE contents and distribution patterns similar to those of the whole rocks. These intrusive carbonatites display lower platinum group elements and stronger fractionation between Pt and Ir relative to high-Si extrusive carbonatite. This indicates that most intrusive carbonatites may be carbonate cumulates. Maoniuping and Daluxiang in Panxi region are large REE deposits. Hydrothermal fluorite ore veins occur outside of the carbonatite bodies and are emplaced in wallrock syenite. The fluorite in Maoniuping has Sr and Nd isotopes similar to carbonatite. The Daluxiang fluorite shows Sr and REE compositions different from those in Maoniuping. The difference is reflected by both the carbonatites and rock-forming carbonates, indicating that REE mineralization is related to carbonatites. The cumulate processes of carbonate minerals make fractionated fluids rich in volatiles and LREE as a result of low partition coefficients for REE between carbonate and carbonatite melt and an increase from LREE to HREE. The carbonatite-derived fluid has interacted with wallrock to form REE ore veins. The amount of carbonatite dykes occurring near the Bayan Obo orebodies may support the same mineralization model, i.e. that fluids evolved from the carbonatite dykes reacted with H8 dolomite marble, and thus the different REE and isotope compositions of coarse- and fine-grained dolomite may be related to reaction processes.

  1. The Genesis of a Trauma Performance Improvement Plan.

    Science.gov (United States)

    Pidgeon, Kristopher

    2015-01-01

    The purpose of this article is to assist the trauma medical and program director with developing a performance improvement and patients safety plan (PIPS), which is a required component of a successful trauma verification process by the American College of Surgeons. This article will review trauma quality standards and will describe in detail the required elements of a successful trauma center's performance improvement plan including a written comprehensive plan that outlines the mission and vision of the PIPS Program, authority of the PIPS Program, PIPS Program Committee reporting structure to the other hospital committees, list of required PIPS multidisciplinary team members, the operational components of the utilized data management system (trauma registry), list of indicators/audit filters, levels of review, peer determinations, corrective action plan with implementation, event resolution, and reevaluation. Strategies to develop a successful trauma performance improvement plan are presented.

  2. The Genesis of Public Relations in British Colonial Practice.

    Science.gov (United States)

    Smyth, Rosaleen

    2001-01-01

    Demonstrates how the British Colonial Office employed public relations strategies as they administered the British colony of Northern Rhodesia before, during, and after World War II. Demonstrates how civil servants in London and colonial officials implemented public relations policies, strategies, and tactics on an ad hoc basis, covering political…

  3. Genesis, challenges and opportunities for colloidal lead halide perovskite nanocrystals

    Science.gov (United States)

    Akkerman, Quinten A.; Rainò, Gabriele; Kovalenko, Maksym V.; Manna, Liberato

    2018-05-01

    Lead halide perovskites (LHPs) in the form of nanometre-sized colloidal crystals, or nanocrystals (NCs), have attracted the attention of diverse materials scientists due to their unique optical versatility, high photoluminescence quantum yields and facile synthesis. LHP NCs have a `soft' and predominantly ionic lattice, and their optical and electronic properties are highly tolerant to structural defects and surface states. Therefore, they cannot be approached with the same experimental mindset and theoretical framework as conventional semiconductor NCs. In this Review, we discuss LHP NCs historical and current research pursuits, challenges in applications, and the related present and future mitigation strategies explored.

  4. Microbiological processes in relation to ore genesis, ch. 6

    International Nuclear Information System (INIS)

    Trudinger, P.A.

    1976-01-01

    The stable isotope compositions of natural sulphur-containing minerals, as used in speculations on their modes of origin, are reviewed. The fractionation of stable sulphur isotopes taking place to varying extents during both chemical and biological (bacterial) transformations, and kinetic and equilibrium isotope effects are discussed. Sulphur isotope compositions of various deposits, for which a biogenic origin has been prposed, are given. Attention is paid to various models in which the isotopic effects for sulphite and sulphate reduction are considered

  5. Bible, ecology and sustainable development: A reading of Genesis 1 ...

    African Journals Online (AJOL)

    Ilorin Journal of Religious Studies. Journal Home · ABOUT THIS JOURNAL · Advanced Search · Current Issue · Archives · Journal Home > Vol 1, No 2 (2011) >. Log in or Register to get access to full text downloads.

  6. Genesis and Development of the Concept of Evolution

    Directory of Open Access Journals (Sweden)

    Hilde Sánchez Morales

    2016-02-01

    Full Text Available Darwin's evolutionary theory, on the date of the publication of On the Origin of Species (1859, immediately attracted the attention, but received unanimous acceptance. Many considered it contrary to religious orthodoxy and a threat that threatened the traditional ideological nature. Others agreed with restrictions and other taken it as absolute truth. Admittedly that the educated opinion of the Victorian Era was strongly conservative and hostile to anything that deviated from orthodoxy. To this we must add that Darwin's approach violated the concept of nature hitherto recognized; so that by broad sectors of the church's reaction ware very aggressive. The discussions and publications on this subject have become especially visible on the occasion of the celebration, in 2009, the bicentennial of the birth of Charles Robert Darwin.

  7. INITIAL STAGES OF CARBON GENESIS IN THE UNIVERSE

    Directory of Open Access Journals (Sweden)

    A.L. Vereshchagin

    2004-12-01

    Full Text Available The formation possibility of the most widespread carbon compounds had been showed on the base of detonation nanodiamonds thermodynamic data. These reactions may play a key role in the life origin and in the atmosphere formation of the Solar system giant planets

  8. Genesis and Evolution of the Nursing and Midwifery Program

    African Journals Online (AJOL)

    managed all of those changes. Lessons Learned. Developing an effective partnership between national nursing leadership and foreign academic institutions requires flexibility, respect, and thoughtful planning. Conclusions. The Rwanda HRH Nursing and Midwifery Program is a remarkable example of professional ...

  9. Genesis: A Framework for Achieving Software Component Diversity

    Science.gov (United States)

    2007-01-01

    correctly—the initial filters develop to fix the Hotmail vulnerability could be circumvented by using alternate character encodings4. Hence, we focus on...Remotely Exploitable Cross-Site Scripting in Hotmail and Yahoo, (March 2004); http://www.greymagic.com/security/advisories/gm005-mc/. 4...EyeonSecurity, Microsoft Passport Account Hijack Attack: Hacking Hotmail and More, Hacker’s Digest. 5. Y.-W. Huang et al., Web Application Security Assessment by

  10. On the stability and the genesis of the electron

    International Nuclear Information System (INIS)

    Yadava, K.S.

    1976-01-01

    The present paper intends to develop a self-consistent field theory of the electron, purely within the realm of classical electrodynamics, which accounts for its existence, its finite size, its charge distribution and its stability. It is shown that an electron can be interpreted as a small region of the field (of the order of 10 - 15m) in which the field values are extremely great. These small regions of the field which would correspond to our usual notion of particles are known as bunched fields. Such bunched fields have been constructed here by finding a discrete number of solutions for Poisson's equation in electrostatics, which are everywhere singularity free, static and spherically symmetric in the domain 0 approximately equal to γ approximately infinity. The corresponding electric fields are also regular everywhere. Both the charge and the mass of the particle are then completely expressed in terms of these regular fields. The theory developed accounts for the existence of the electron, its finite size, its charge distribution and its stability

  11. Genesis of regulatory and legal provision of financial safety

    Directory of Open Access Journals (Sweden)

    M.V. Pataridze-Vyshynska

    2016-07-01

    Full Text Available The article describes the main problems that concern regulatory and legal provision of financial safety. The scientific groundwork of researchers of this matter in Ukraine is analyzed and its gaps are revealed. The state competences concerning the regulation of financial safety are investigated. The legal provision of financial safety in a retrospective section is considered. The short characteristic of the main legal instruments that make the subsoil for formation of financial safety environment is provided. The main stages of legislative process of ensuring financial safety are found out. The paradigm of financial safety formation is generalized. The possibilities of ensuring financial safety in different areas of the state financial policy through the definition of problem aspects and ways of their decision are defined. It is certain that the problem of protection of national interests in the economic sphere is rather actual, especially in formation of financial safety environment in modern conditions. This problem is subject to further investigation of both lawmakers and scientists-economists.

  12. Academic Ranking--From Its Genesis to Its International Expansion

    Science.gov (United States)

    Vieira, Rosilene C.; Lima, Manolita C.

    2015-01-01

    Given the visibility and popularity of rankings that encompass the measurement of quality of post-graduate courses, for instance, the MBA (Master of Business Administration) or graduate studies program (MSc and PhD) as do global academic rankings--Academic Ranking of World Universities-ARWU, Times Higher/Thomson Reuters World University Ranking…

  13. Genesis of a Joint Gallery of Sport Art.

    Science.gov (United States)

    Kozar, Andrew J.

    1989-01-01

    The University of Pennsylvania's dual sport art gallery showcases the work of R. Taft McKenzie and Joe Brown, two of the premier sport artists of our time. This article briefly outlines the artists' careers and describes the planning which led to establishment of the gallery. (IAH)

  14. Nanotechnology in neurology: Genesis, current status, and future prospects

    Directory of Open Access Journals (Sweden)

    Paurush Ambesh

    2015-01-01

    Full Text Available Nanotechnology is a promising, novel field of technological development. There is great potential in research and clinical applications for neurological diseases. Here we chronicle the inception of nanotechnology, discuss its integration with neurology, and highlight the challenges in current application. Some of the problems involving practical use of neuronanotechnology are direct biological toxicity, visualization of the nanodevice, and the short life expectancy of nanomachinery. Neuron cell therapy is an upcoming field for the treatment of challenging problems in neurology. Peptide nanofibers based on amphiphilic molecules have been developed that can autoregulate their structure depending on the conditions of the surrounding milieu. Such frameworks are promising for serving as drug delivery systems or communication bridges between damaged neurons. For common disabling diseases such as Alzheimer′s disease (AD, Parkinson′s disease (PD, amyotrophic lateral sclerosis (ALS, and multiple sclerosis (MS, recent developments have seen revolutionary nanotech-based novelties, which are discussed here in detail. Bioimaging integrated with nanoneuromedicine has opened up new doors for cancer and infection therapeutics.

  15. Genesis of uranium deposits of the Tono Mine, Japan

    International Nuclear Information System (INIS)

    Katayama, N.; Kubo, K.; Hirono, S.

    1974-01-01

    The uranium deposits of the Tono mine, Gifu Prefecture, Japan, occur in the basal part of the Toki group of Miocene age, and are distributed in the tributaries or at the head of channels on the plane of unconformity under the formation. These features characterize the basal ground-water type of uranium deposit, and they are unique in that their typical ore mineral is a zeolite of the heulandite-clinoptilolite group, uranium being adsorbed in it. The paper presents the history of formation of the Tsukiyoshi deposits, the most intensely explored in the Tono mine. The matrices of conglomerates and sandstones of the Toki group usually contain tuffaceous material, which has been montmorillonitized or zeolitized diagenetically. The conduit of uranium-bearing ground waters that migrated from the basement granites into the Tertiary sediments was controlled by the impermeable barriers, which are rocks in which montmorillonite predominated, or by the Tsukiyoshi fault, as well as by channel structures. Where the waters became rather stagnant, uranium was adsorbed in zeolite from them. Enrichment of uranium further proceeded locally as follows. Pyrite was oxidized to produce sulphuric acid solution which leached the uranium that had been adsorbed in zeolite. The pH of the uranium-rich solution became higher and higher in the course of migration and, as soon as it reached about 4, the uranium in the solution was again adsorbed in zeolite, the uranium content of which may have been enriched up to 0.9%. Coffinites have been formed where uranium was accumulated over the adsorption capacity of zeolite or where strongly reducing conditions were maintained by carbonaceous matter. (author)

  16. The new genesis of knowledge: Shared leadership for knowledge development

    NARCIS (Netherlands)

    Crielaard, J.P.; Wubben, E.F.M.; Omta, S.W.F.

    2012-01-01

    Today’s issues, like sustainable growth, are demanding for leaders, employees, knowledge and organisational innovation. Leadership literature until now is restrained by a hierarchical bias. This study takes an Ecologic System Model, and tests the contribution of shared leadership, self-directive

  17. The State of Kenyan Historiography: Its Genesis, Evolution and ...

    African Journals Online (AJOL)

    The writing of history as academic discipline in Kenya is relatively very recent. This is however not to deny its invaluable antecedents characterized by oral histories as well as written accounts. This paper thus provides an appraisal of this historiography highlighting critical issues and concerns at each moment, which either ...

  18. The Genesis and Evolution of Pre-vocational Education: England.

    Science.gov (United States)

    Marshall, Stephanie

    1990-01-01

    Traces the history of English prevocational education since 1870, examining four pieces of educational legislation. Outlines the recurring debate over the extent utilitarianism should define education. Focuses on political and economic requirements that fostered utilitarianism. Evaluates the act's technical and vocational education initiative. (CH)

  19. RECIFE: NOTES AROUND THE GENESIS OF A FIELD CULTURAL

    Directory of Open Access Journals (Sweden)

    Flávio Weinstein Teixeira

    2014-12-01

    Full Text Available Regard to the discussion of artistic modernity in Brazil, the article presents a panel of intellectual and cultural debates in Recife (1920-50, in order to give weight to the power lines, literate sociability, as well as the spaces of recognition and consecration the artistic/intellectual making that resulted in a specific dynamic to the cultural field of the city. Therefore, give special attention to the actions of a local theater group (TEP – Pernambuco Students’s Theatre and their contribution to the renewal of artistic and intellectual practices.

  20. Genesis and growth of internal microstructures of manganese nodule

    Digital Repository Service at National Institute of Oceanography (India)

    Banakar, V.K.; Tarkian, M.

    tension of the 2 adjacent colloidal precipitate surfaces which have a tendency to grow into a spheroid, probably similar to phenomenon of drop formation. Detrital components within the nodule material identified include heavy titanium minerals, viz...

  1. Genesis of early Cambrian phosphorite of Krol Belt, Lesser Himalaya

    Digital Repository Service at National Institute of Oceanography (India)

    Mazumdar, A.; Banerjee, D.M.

    depositional en- vironment. Similar shallow marine character for Late Vendian and Early Cambrian phosphorites have been recorded from Yangtze Basin (South China), Khub- shugul Basin (Mongolia), Karatau Basin (Kazakh- stan), Soltaniah Basin (Iran), Tal Basin.... This characteris- tic of microbial mats may enable them to bind the franco- lite microcrysts on their surfaces, giving rise to microbial laminations. The capacity of microbiota, viz. bacteria, fungi and cyanobacterial mat-forming microphytes to trap and bind...

  2. [Genesis of hospital nursing in Goiás State].

    Science.gov (United States)

    Guimarães, Celma Martins; de Andrade, Ilidiana Miranda

    2005-01-01

    The Hospital de Caridade São Pedro de Alcântara was created in the City of Goiás, being the first hospital institution implanted in the state. The work purposes to understand the historical-social context in which the "São Pedro" was implanted, looking for information about the structure and operation, especially what concerns to the nursing. The used approach was the dialectics. The results demonstrated the existence of ten nursing workers and that those were separate to patients' attendance according to gender. The work delivered by the male workers was better remunerated than the one delivered by female workers. The hospital and their servants, gradually, were assuming the responsibility for the ordering and cleanliness of the physical spaces, workers, prisioners, burials, etc. The work was arduous and badly paid.

  3. Nonlinear morphoelastic plates I: Genesis of residual stress

    KAUST Repository

    McMahon, J.; Goriely, A.; Tabor, M.

    2011-01-01

    Volumetric growth of an elastic body may give rise to residual stress. Here a rigorous analysis is given of the residual strains and stresses generated by growth in the axisymmetric Kirchhoff plate. Balance equations are derived via the Global Constraint Principle, growth is incorporated via a multiplicative decomposition of the deformation gradient, and the system is closed by a response function. The particular case of a compressible neo-Hookean material is analyzed, and the existence of residually stressed states is established. © SAGE Publications 2011.

  4. Contributions to the Genesis and Progress of ICF

    Energy Technology Data Exchange (ETDEWEB)

    Nuckolls, J H

    2006-02-15

    Inertial confinement fusion (ICF) has progressed from the detonation of large-scale fusion explosions initiated by atomic bombs in the early 1950s to final preparations for initiating small-scale fusion explosions with giant lasers. The next major step after ignition will be development of high performance targets that can be initiated with much smaller, lower cost lasers. In the 21st century and beyond, ICF's grand challenge is to develop practical power plants that generate low cost, clean, inexhaustible fusion energy. In this chapter, I first describe the origin in 1960-61 of ICF target concepts, early speculations on laser driven 'Thermonuclear Engines' for power production and rocket propulsion, and encouraging large-scale nuclear explosive experiments conducted in 1962. Next, I recall the 40-year, multi-billion dollar ignition campaign - to develop a matched combination of sufficiently high-performance implosion lasers and sufficiently stable targets capable of igniting small fusion explosions. I conclude with brief comments on the NIF ignition campaign and very high-performance targets, and speculations on ICF's potential in a centuries-long Darwinian competition of future energy systems. My perspectives in this chapter are those of a nuclear explosive designer, optimistic proponent of ICF energy, and Livermore Laboratory leader. The perspectives of Livermore's post 1970 laser experts and builders, and laser fusion experimentalists are provided in a chapter written by John Holzrichter, a leading scientist and leader in Livermore's second generation laser fusion program. In a third chapter, Ray Kidder, a theoretical physicist and early laser fusion pioneer, provides his perspectives including the history of the first generation laser fusion program he led from 1962-1972.

  5. Compositional variation and genesis of ferromanganese crusts of ...

    Indian Academy of Sciences (India)

    incorporation of various metals in the Fe–Mn crusts ... shown to readily oxidize to their higher oxidation state on adsorption to ... metal species are those of the transition group com- ...... Banakar V K 1990 Uranium–thorium isotopes and tran-.

  6. The Genesis Account of Creation and its Relationship to Cosmogony.

    African Journals Online (AJOL)

    This paper concerns itself with the issue of the account of creation and its relationship to cosmogony. In this jet age when western education has broadened people's mind, there is a strong desire to know the true origin of man and the universe. It goes a step further to highlight various concepts of creation, pointing out their ...

  7. The paradoxical genesis of too-big-to-fail

    Directory of Open Access Journals (Sweden)

    Thomas S. Umlauft

    2014-03-01

    Full Text Available At least since the Global Financial Crisis of 2007-2009, the problem of too-big-to-fail (TBTF has received widespread attention. The research conducted in this context has, however, generally focused on the econometric aspect and the contribution of the TBTF doctrine to the financial crisis of 2007-2009, while the economic historical approach has been confined to tracing the doctrine to its first appearance. This paper attempts to fill this gap in the academic literature by offering an explanation for why, as opposed to how, the TBTF doctrine has developed. This paper identifies the US population’s distrust and at times hostility against the prospect of concentration of power in large financial institutions as the causal factor leading to the TBTF phenomenon. The resulting socially non-optimal regulation favoured a fragmented and fragile banking system based on small unit banks at the cost of more diversified branch banks. The Great Depression impressively highlighted the deep structural flaws of the US banking system. At the same time, however, it caused a shift in the public opinion, which had generally been opposed to deposit insurance, and thereby aligned the public interest with that of small banks, which would profit most from deposit insurance. The newly acquired public and political support enabled weak unit banks to lobby successfully against reforming the banking structure and instead for the adaption of federal deposit insurance. However, the Federal Deposit Insurance Corporation (FDIC only addressed the symptoms of the weak banking industry but not its causes. Moreover, the strongly biased FDIC policies have generally favoured creditors at large banks, which ultimately led to the TBTF doctrine which, in turn, provided banks with a non-technical incentive to grow in size in order to gain TBTF protection. Initially aimed at preserving the US financial landscape based on small unit banks, the FDIC as the main conduit for TBTF rescues thus became the main driver for big bank corporate welfare. Deposit insurance gave rise to TBTF and, at the same time, put small banks deemed “too-small-to-safe” at a competitive disadvantage, further accelerating the trend towards increasingly large and complex banks.

  8. Chromosomes in the genesis and progression of ependymomas

    DEFF Research Database (Denmark)

    Rogatto, S R; Casartelli, C; Rainho, C A

    1993-01-01

    chromosomes in three cases. Structural rearrangements of chromosome 2 were a finding for all cases and involved loss of material at 2q32-34. Other structural chromosome abnormalities detected involved chromosomes 4, 6, 10, 11, 12, and X. We also reviewed data on 22 cases previously reported....

  9. Hermeneutics in identity formation: Paul's use of Genesis in ...

    African Journals Online (AJOL)

    Test

    2010-08-06

    Aug 6, 2010 ... psychological functioning and large-scale social processes .... the Christian's life of service to God as a spiritual battle; however, military terms dominate .... subscribes to Dunn's thesis that Paul's law-polemic addressed Jewish ...

  10. Conclusion - Admixture elements as indicators of fluorite genesis

    International Nuclear Information System (INIS)

    Fayziev, A.R.

    2002-01-01

    The information obtained during scientific researches was generalized and analyzed. It was defined that studying of qualitative composition and quantitative content revealed the geochemical features of fluorite.

  11. Late Quaternary fine silt deposits of Jammu, NW Himalaya: Genesis ...

    Indian Academy of Sciences (India)

    ... of Jammu suggest fluvial environment of the deposits wherein the water budget fluctuated. ... the probable source for desert 'loess' of Pakistan. (Rendell et al 1989). ...... the velocity of water is diminished due to loss of flow competence and.

  12. Natural fracking and the genesis of five-element veins

    Science.gov (United States)

    Markl, Gregor; Burisch, Mathias; Neumann, Udo

    2016-08-01

    Hydrothermal Ag-Co-Ni-Bi-As (five-element vein type) ore deposits show very conspicuous textures of the native elements silver, bismuth, and arsenic indicating formation from a rapid, far-from-equilibrium process. Such textures include up to dm-large tree- and wire-like aggregates overgrown by Co-Ni-Fe arsenides and mostly carbonates. Despite the historical and contemporary importance of five-element vein type deposits as sources of silver, bismuth, and cobalt, and despite of spectacular museum specimens, their process of formation is not yet understood and has been a matter of debate since centuries. We propose, based on observations from a number of classical European five-element vein deposits and carbon isotope analyses, that "natural fracking," i.e., liberation of hydrocarbons or hydrocarbon-bearing fluids during break up of rocks in the vicinity of an active hydrothermal system and mixing between these hydrocarbons (e.g., methane and/or methane-bearing fluids) and a metal-rich hydrothermal fluid is responsible for ore precipitation and the formation of the unusual ore textures and assemblages. Thermodynamic and isotope mixing calculations show that the textural, chemical, and isotopic features of the investigated deposits can entirely be explained by this mechanism.

  13. FEL-Oscillator simulations with Genesis 1.3

    NARCIS (Netherlands)

    Karssenberg, J.G.; van der Slot, Petrus J.M.; Verschuur, Jeroen W.J.; Volokhine, I.; Boller, Klaus J.

    2006-01-01

    Modeling free-electron laser (FEL) oscillators requires calculation of both the light-beam interaction within the undulator and the propagation of the light outside the undulator. We present a paraxial Optical Propagation Code (OPC) based on the Spectral Method and Fresnel Diffraction Integral,

  14. Brightness/darkness induction and the genesis of a contour

    Directory of Open Access Journals (Sweden)

    Sergio eRoncato

    2014-10-01

    Full Text Available Visual contours often result from the integration or interpolation of fragmented edges.The strength of the completion increases when the edges share the same contrast polarity (CP. Here we demonstrate that the appearance in the perceptual field of this integrated unit, or contour of invariant CP, is concomitant with a vivid brightness alteration of the surfaces at its opposite sides. To observe this effect requires some stratagems because the formation in the visual field of a contour of invariant CP normally engenders the formation of a second contour and then the rise of two streams of induction signals that interfere in different ways. Particular configurations have been introduced that allow us to observe the induction effects of one contour taken in isolation. I documented these effects by phenomenological observations and psychophysical measurement of the brightness alteration in relation to luminance contrast. When the edges of the same CP complete to form a contour, the background of homogeneous luminance appears to dim at one side and to brighten at the opposite side (in accord with the CP. The strength of the phenomenon is proportional to the local luminance contrast. This effect weakens or nulls when the contour of the invariant CP separates surfaces filled with different grey shades.These conflicting results stimulate a deeper exploration of the induction phenomena and their role in the computation of brightness contrast. An alternative perspective is offered to account for some brightness illusions and their relation to the phenomenal transparency. The main assumption asserts that, when in the same region induction signals of opposite CP overlap, the filling-in are blocked unless the image is stratified into different layers, one for each signal of the same polarity. Phenomenological observations document this solution by the visual system

  15. THE GENESIS OF THE FUNCTIONS OF GOVERNMENT DEBT SECURITIES

    Directory of Open Access Journals (Sweden)

    V. Osetskyi

    2015-06-01

    Full Text Available Government borrowings appear at a certain stage of development the economic system. Governments used loans many centuries ago because there are often occurred situations when borrowings were the only way to attract additional financial resources. The preconditions for government loans from the position of creditors are also important. These, in particular, include: the availability of subjects that have the temporarily available funds; investor confidence in the state, that stimulating their interest in buying government debt securities; state’s ability to repay its obligations and so on. Thus, the article deals with the basic prerequisites of the government securities market and its function at different stages of develop-ment of economic relations. So, it was found, that the main functions of local borrowing in XIV-XX centuries include the following: fiscal, public debt management, improved economic situation in some areas and repayment of previously issued loans. In modern conditions the functions of government securities have expanded and include: regulation of the money market and stock market, smoothing unevenness of funds flow to the budget, funding various pro-grams, support the liquidity of financial institutions. The author also highlights that objective necessity of using government borrowing associated with the presence of contradictions between the existing needs of society and the state’s capacity to satisfy them within existing financial re-sources. And in such situations government securities are a means of mobilizing additional financial resources to the state budget.

  16. Cognitive dissonance as an explanation of the genesis, evolution ...

    African Journals Online (AJOL)

    The steady erosion of support for this flagrant HIV denialism, together with the rise of neoliberal thinking in the ANC, would lead to the evolution of this biological denialism into a form of treatment denialism. This ideology argued against the widespread provision and use of antiretroviral treatment. Empirical evidence is ...

  17. Tablatures : Exposition photographique d'instruments virtuels GENESIS

    OpenAIRE

    Cadoz, Claude

    2012-01-01

    International audience; Le concept de « composer le son », introduit et expérimenté musicalement par Jean-Claude Risset à partir des années 1960 par la synthèse de sons par ordinateur, prolonge, élargit, dépasse et transforme l'acte d'écriture pour des instruments mécano-acoustiques. Il ne résout cependant pas la question de l'instrumentalité, particulièrement mise à mal avec l'ordinateur. Les technologies de modélisation et de simulation numériques pour « écrire l'instrument pour le composer...

  18. Contributions to the Genesis and Progress of ICF

    International Nuclear Information System (INIS)

    Nuckolls, J.H.

    2006-01-01

    Inertial confinement fusion (ICF) has progressed from the detonation of large-scale fusion explosions initiated by atomic bombs in the early 1950s to final preparations for initiating small-scale fusion explosions with giant lasers. The next major step after ignition will be development of high performance targets that can be initiated with much smaller, lower cost lasers. In the 21st century and beyond, ICF's grand challenge is to develop practical power plants that generate low cost, clean, inexhaustible fusion energy. In this chapter, I first describe the origin in 1960-61 of ICF target concepts, early speculations on laser driven 'Thermonuclear Engines' for power production and rocket propulsion, and encouraging large-scale nuclear explosive experiments conducted in 1962. Next, I recall the 40-year, multi-billion dollar ignition campaign - to develop a matched combination of sufficiently high-performance implosion lasers and sufficiently stable targets capable of igniting small fusion explosions. I conclude with brief comments on the NIF ignition campaign and very high-performance targets, and speculations on ICF's potential in a centuries-long Darwinian competition of future energy systems. My perspectives in this chapter are those of a nuclear explosive designer, optimistic proponent of ICF energy, and Livermore Laboratory leader. The perspectives of Livermore's post 1970 laser experts and builders, and laser fusion experimentalists are provided in a chapter written by John Holzrichter, a leading scientist and leader in Livermore's second generation laser fusion program. In a third chapter, Ray Kidder, a theoretical physicist and early laser fusion pioneer, provides his perspectives including the history of the first generation laser fusion program he led from 1962-1972.

  19. Genesis of unified models from Majorana-Weyl fields

    International Nuclear Information System (INIS)

    Budini, P.; Furlan, P.

    1977-07-01

    It is proposed that all forms of interaction arise from elementary interactions between Weyl-Majorana fields. Weak interactions due to the high masses of the intermediate bosons are practically identical to the elementary interactions. Strong and electromagnetic interactions arise at larger distance, where dynamic determines both masses and symmetry. In the frame of these ideas, Pati-Salam and Fritzsch-Minkowski type of unified models are constructed starting from eight Weyl-Majorana fields. Fractional charges for quarks, integer charges for lepton and regularization of q.e.d. arise naturally from the model. Unobserved transitions (μ→e + γ, p→ leptons) may be ascribed to properties of the elementary fields (handedness) rather than very high W masses

  20. From lepton protoplasm to the genesis of hadrons

    Science.gov (United States)

    Eliseev, S. M.; Kosmachev, O. S.

    2016-01-01

    Theory of matter under extreme conditions opens a new stage in particle physics. It is necessary here to combine Dirac's elementary particle physics with Prigogine's dynamics of nonequilibrium systems. In the article we discuss the problem of the hierarchy of complexity. What can be considered as the lowest level of the organization of extreme matter on the basis of which the self-organization of the complex form occur?

  1. Mathematical Observations: The Genesis of Mathematical Discovery in the Classroom

    Science.gov (United States)

    Beaugris, Louis M.

    2013-01-01

    In his "Proofs and Refutations," Lakatos identifies the "Primitive Conjecture" as the first stage in the pattern of mathematical discovery. In this article, I am interested in ways of reaching the "Primitive Conjecture" stage in an undergraduate classroom. I adapted Realistic Mathematics Education methods in an…

  2. Hermeneutics in identity formation: Paul's use of Genesis in ...

    African Journals Online (AJOL)

    Paul's hermeneutics, in dealing with the scriptures and traditions of Israel and his concern for a specific identity for the communities he interacted with, require attention for the reciprocal, interrelationship between hermeneutics and identity in his letters. Paul's quotations from and allusions to the scriptures of Israel but also ...

  3. On spinor geometry: A genesis of extended supersymmetry

    International Nuclear Information System (INIS)

    Budini, P.

    1980-08-01

    It is conjectured that euclidean geometry should be derived from spinor geometry through the equivalence of simple semispinor with isotropic semi n-vectors. The only tensors of complex 2n dimensional Euclidean space Esub(c)sup(2n) should then be: isotropic n - vectors and their intersections. Esub(c) 4 spinor geometry generates two isotropic semi bivectors equivalent to the semispinors of Esub(c) 4 (their geometrical properties are those of light propagating in vacuum), and their intersection: an isotropic vector (possibly representing momenta of massless particle and/or light rays); but no scalar, pseudoscalar or pseudovector is generated. In order to generate vectors outside the light cone in Msup(3.1) one needs not less than Esub(c) 6 spinor geometry which also generates Lorentz pseudoscalars and non isotropic pseudovectors and tensors. Besides, Dirac spinor should then always appear in doublets in Msup(3.1). Furthermore the mere geometrical structure of Esub(c) 6 spinor geometry seems to suggest formally, both Poincare (extended) and conformal supersymmetry. The suggested spinor-geometrical approach privileges the elementary role of semispinors. Its relevance for the real world should be manifested by the privileged role of semispinors in elementary interactions as in fact seems to be the case with Lorentz semispinors in weak interactions (and could perhaps also be the case for strong ones where conformal semispinors (or twistors) could be the interacting spinor fields). (author)

  4. Genesis of felsic plutonic magmas and their igneous enclaves

    DEFF Research Database (Denmark)

    Clemens, John D.; Maas, Roland; Waight, Tod Earle

    2016-01-01

    -type Pyalong pluton was emplaced, apparently along an east-west-orientated fracture zone. Around 367 Ma, the main I-type Baynton pluton intruded as numerous shallow-dipping sheets. The last plutonic event was the intrusion of the broad, thin, flat-lying, and crosscutting sheet of the I-type Beauvallet pluton...... the relatively high abundance of igneous-textured microgranular enclaves (MEs). The MEs show neither chemical nor isotope mixing trends with each other or with the host magmas. Variations in the Baynton magmas were derived from the heterogeneity of the source terrane, with individual magma batches formed from...

  5. A livraria Garnier e a história dos livros infantis no Brasil: gênese e formação de um campo literário (1858-1920 - Garnier bookshop and the history of the books for children in Brazil: genesis and development of a literary field

    Directory of Open Access Journals (Sweden)

    Andréa Borges Leão

    2011-04-01

    Full Text Available Resumo O artigo analisa as coleções para crianças e jovens apresentadas nos catálogos de venda da livraria carioca de Baptiste-Louis Garnier para o ano de 1858, e de seus sucessores, para 1920. Como modelo da política de exportação da indústria editorial francesa e, com isso, de formação do patrimônio de obras necessário ao desenvolvimento de nosso comércio livreiro e autonomia literária, os Garnier apostaram na longevidade do gênero "clássicos infantis", reeditando-os e adaptando-os, o que demonstra uma intrincada rede de relações entre sua filial latino-americana e a matriz francesa, bem como os efeitos de um trabalho de formação do gosto literário das crianças e jovens brasileiros. Palavras-Chave: História editorial; literatura infantil; coleções infantis e juvenis; comércio livreiro.   GARNIER BOOKSHOP AND THE HISTORY OF THE BOOKS FOR CHILDREN IN BRAZIL: GENESIS AND DEVELOPMENT OF A LITERARY FIELD Abstract This paper analysis the collections of books for children and youths found in the catalogues of Baptiste-Louis Garnier bookshop in the year of 1858, and further collections, with new editors, until the year of 1920. Being a model of the French polices for the editorial market, and in an attempt of developing the Brazilian literary market, the Garnier bookshop invested in the classic books for children, re-editing and adapting them. Such behavior shows an intricate relationship between the Latin-American branch and its French main office as well as the way their polices influenced the literary taste of children and youths in Brazil. Keywords: editorial history; children literature; children and youths collections; bookshops.   LA LIBRERÍA GARNIER Y LA HISTORIA DE LOS LIBROS PARA NIÑOS EN BRASIL: GÉNESIS Y FORMACIÓN DE UN CAMPO LITERARIO (1858-1920 Resumen El texto analiza las colecciones para niños y jóvenes presentadas en los catálogos de venta de la librería carioca de Baptiste-Louis Garnier para el a

  6. Efeitos da prostaglandina E1 (PGE1 na gênese de capilares sanguíneos em músculo esquelético isquêmico de ratos: estudo histológico Effects of prostaglandin E1 (PGE1 in the genesis of blood capillaries in rat ischemic skeletal muscle: histological study

    Directory of Open Access Journals (Sweden)

    Dorival Moreschi Jr.

    2007-12-01

    purpose. OBJECTIVE: To study morphologic aspects in the genesis of blood capillaries in the lower limb skeletal muscle of rats submitted to ischemia under the action of intramuscular (IM or endovenous (EV PGE1. METHODS: Forty-eight Wistar-UEM rats were randomly distributed into three groups of 16, equally redistributed into two subgroups, observed at the 7th and 14th days as follows: one control group, which had only limb ischemia; one group with ischemia and IM injection of PGE1; and one group with ischemia and EV injection of PGE1. To analyze the results, hematoxylin-eosin (HE and immunohistochemical staining were used. RESULTS: There was a statistically significant increase in the number of capillaries in the subgroups using IM or EV PGE1, through counting in the samples containing HE staining. Immunostaining was not efficient for the quantification of capillaries. CONCLUSIONS: IM or EV PGE1 resulted in an increase in number of capillaries in the skeletal muscle of rats submitted to ischemia after 14 days of observation, which was histologically identifiable through HE staining. Immunostaining was not successful in establishing a correlation with the increase in vessels found in HE staining.

  7. Preparation and characterization of a hetero functional system of gold nanoparticles labeled with 99mTc and conjugated to the sequence Arg-Gly-Asp for detection in vivo of angio genesis and evaluation of their toxicity in Hyalella aztec

    International Nuclear Information System (INIS)

    Morales A, E.

    2012-01-01

    Integrin s play critical roles in many physiological processes including angio genesis and also contribute to pathological events such as tumor invasion and metastasis. The α v β 3 integrin is expressed in normal endothelial cells but it is over-expressed in the tumor neo vasculature. Peptides based on the Arginine-Glycine-Aspartic acid (RGD) sequence have been reported as molecules with high affinity and selectivity for the α v β 3 integrin. Recent studies have demonstrated that conjugating peptides to gold nanoparticles (AuNP) produces biocompatible and stable multifunctional systems with target-specific molecular recognition due to multivalent effects produced by multiple simultaneous interactions between peptides and their receptors. The first aim of this research was to prepare a m ultimeric system of 99m Tc labeled gold particles conjugated to c[RGDfK(C)] and to evaluate its biological behavior as a potential radiopharmaceutical for molecular imaging of α v β 3 tumor expression. Hidrazinonicotinamide-G GC (HYNIC-G GC) and C[RGDfK(C)] peptides were synthesized and conjugated to AuNP (20 nm) by means of spontaneous reaction of the thiol groups of cysteine. The nano conjugate was characterized by transmission electron microscopy, Fourier transform-infrared, Ultraviolet-vis, X-ray photoelectron spectroscopy and Raman spectroscopy. To obtain 99m Tc-HYNIC-G GC-AuNP-c[RGDfK(C)], the 99m Tc-HYNIC-G GC radio peptide was first prepared and added to the AuNP solution followed by c[RGDfK(C)]. Radiochemical purity (Rp) was determined by size-exclusion HPLC and I TLC-Sg analyses. In vitro binding studies were carried out in α v β 3 receptor-positive C6 glioma cancer cells. Biodistribution studies were accomplished in athymic mice with C6-induced tumors with blocked and non blocked receptors, and images were obtained using a micro-SPECT/CT. Transmission electron microscopy and spectroscopy techniques demonstrated that AuNP were functionalized with peptides. Rp was

  8. Preparation and characterization of a hetero functional system of gold nanoparticles labeled with {sup 99m}Tc and conjugated to the sequence Arg-Gly-Asp for detection in vivo of angio genesis and evaluation of their toxicity in Hyalella aztec; Preparacion y caracterizacion de un sistema heterofuncional de nanoparticulas de oro marcadas con Tecnecio-99m y conjugadas a la secuencia Arg-Gly-Asp para la deteccion in vivo de angiogenesis y la evaluacion de su toxicidad en Hyalella azteca

    Energy Technology Data Exchange (ETDEWEB)

    Morales A, E.

    2012-07-01

    Integrin s play critical roles in many physiological processes including angio genesis and also contribute to pathological events such as tumor invasion and metastasis. The {alpha}{sub v}{beta}{sub 3} integrin is expressed in normal endothelial cells but it is over-expressed in the tumor neo vasculature. Peptides based on the Arginine-Glycine-Aspartic acid (RGD) sequence have been reported as molecules with high affinity and selectivity for the {alpha}{sub v}{beta}{sub 3} integrin. Recent studies have demonstrated that conjugating peptides to gold nanoparticles (AuNP) produces biocompatible and stable multifunctional systems with target-specific molecular recognition due to multivalent effects produced by multiple simultaneous interactions between peptides and their receptors. The first aim of this research was to prepare a m ultimeric system of {sup 99m}Tc labeled gold particles conjugated to c[RGDfK(C)] and to evaluate its biological behavior as a potential radiopharmaceutical for molecular imaging of {alpha}{sub v}{beta}{sub 3} tumor expression. Hidrazinonicotinamide-G GC (HYNIC-G GC) and C[RGDfK(C)] peptides were synthesized and conjugated to AuNP (20 nm) by means of spontaneous reaction of the thiol groups of cysteine. The nano conjugate was characterized by transmission electron microscopy, Fourier transform-infrared, Ultraviolet-vis, X-ray photoelectron spectroscopy and Raman spectroscopy. To obtain {sup 99m}Tc-HYNIC-G GC-AuNP-c[RGDfK(C)], the {sup 99m}Tc-HYNIC-G GC radio peptide was first prepared and added to the AuNP solution followed by c[RGDfK(C)]. Radiochemical purity (Rp) was determined by size-exclusion HPLC and I TLC-Sg analyses. In vitro binding studies were carried out in {alpha}{sub v}{beta}{sub 3} receptor-positive C6 glioma cancer cells. Biodistribution studies were accomplished in athymic mice with C6-induced tumors with blocked and non blocked receptors, and images were obtained using a micro-SPECT/CT. Transmission electron microscopy and

  9. Differentiating biotic from abiotic methane genesis in hydrothermally active planetary surfaces.

    Science.gov (United States)

    Oze, Christopher; Jones, L Camille; Goldsmith, Jonas I; Rosenbauer, Robert J

    2012-06-19

    Molecular hydrogen (H(2)) is derived from the hydrothermal alteration of olivine-rich planetary crust. Abiotic and biotic processes consume H(2) to produce methane (CH(4)); however, the extent of either process is unknown. Here, we assess the temporal dependence and limit of abiotic CH(4) related to the presence and formation of mineral catalysts during olivine hydrolysis (i.e., serpentinization) at 200 °C and 0.03 gigapascal. Results indicate that the rate of CH(4) production increases to a maximum value related to magnetite catalyzation. By identifying the dynamics of CH(4) production, we kinetically model how the H(2) to CH(4) ratio may be used to assess the origin of CH(4) in deep subsurface serpentinization systems on Earth and Mars. Based on our model and available field data, low H(2)/CH(4) ratios (less than approximately 40) indicate that life is likely present and active.

  10. Biotechnological strategies and tools for Plum pox virus resistance: trans-, intra-, cis-genesis, and beyond

    Science.gov (United States)

    Ilardi, Vincenza; Tavazza, Mario

    2015-01-01

    Plum pox virus (PPV) is the etiological agent of sharka, the most devastating and economically important viral disease affecting Prunus species. It is widespread in most stone fruits producing countries even though eradication and quarantine programs are in place. The development of resistant cultivars and rootstocks remains the most ecologically and economically suitable approach to achieve long-term control of sharka disease. However, the few PPV resistance genetic resources found in Prunus germplasm along with some intrinsic biological features of stone fruit trees pose limits for efficient and fast breeding programs. This review focuses on an array of biotechnological strategies and tools, which have been used, or may be exploited to confer PPV resistance. A considerable number of scientific studies clearly indicate that robust and predictable resistance can be achieved by transforming plant species with constructs encoding intron-spliced hairpin RNAs homologous to conserved regions of the PPV genome. In addition, we discuss how recent advances in our understanding of PPV biology can be profitably exploited to develop viral interference strategies. In particular, genetic manipulation of host genes by which PPV accomplishes its infection cycle already permits the creation of intragenic resistant plants. Finally, we review the emerging genome editing technologies based on ZFN, TALEN and CRISPR/Cas9 engineered nucleases and how the knockout of host susceptibility genes will open up next generation of PPV resistant plants. PMID:26106397

  11. Genesis of carbonate-siliceous-pelitic type uranium deposits in Baoyuan area

    International Nuclear Information System (INIS)

    Guo Baochi; Zhang Daishi; Li Shengxiang; Zhu Jiechen

    1995-01-01

    Based on systematic studies of the regional geology, the fundamental geological characteristics of uranium mineralizations, and according to the researches of uranium source, the REE characteristics, the H,O,C,S isotope compositions, as well as the chronology of uranium metallogenesis of the uranium deposits, the authors consider that the multistage accumulative metallogenesis (especially the hydrothermal superimposed and reworking metallogenesis) is the universal and important uranium metallogenesis in the formation of carbonate-siliceous-pelitic type uranium deposits in the area

  12. The Genesis of Precious and Base Metal Mineralization at the Miguel Auza Deposit, Zacatecas, Mexico

    Science.gov (United States)

    Findley, A. A.; Olivo, G. R.; Godin, L.

    2009-05-01

    The Miguel Auza mine located in Zacatecas State, Mexico, is a vein-type polymetallic epithermal deposit hosted in deformed argillite, siltstone and, greywacke of the Cretaceous Caracol Formation. Silver-rich base metal veins (0.2 m to >1.5 m wide) are spatially associated with the NE-striking, steeply SE- dipping (70-80°) Miguel Auza fault over a strike length of 1.6 km and a depth of 460 m. A 2 km2 monzonitic stock located in the proximity of the mineralized zones, has previously been interpreted as the source of the mineralizing fluids. Four distinct structural stages are correlated with hydrothermal mineral deposition: (I) The Pre-ore stage is characterized by normal faulting, fracturing of host rock, and rotation of bedding planes. This stage consists of quartz, illite, chlorite, +/- pyrite alteration of sedimentary wall rocks. (II) The Pyrite-vein stage is associated with reverse-sense reactivation of early normal faults, dilation of bedding planes/fractures, and deposition of generally barren calcite + pyrite veinlets. (III) The Main-ore stage is related to the development of reverse-fault- hosted massive sulphide veins. During this stage three phases of mineral deposition are recorded: early pyrite and arsenopyrite, intermediate chalcopyrite, pyrite, arsenopyrite, and base metals, and late base metals and Ag-bearing minerals. Associated gangue minerals during the main ore stage are quartz, muscovite, calcite and chlorite. (IV) The Post-ore stage involves late NW-SE striking block faulting, brecciation and calcite veining. Later supergene oxidation of veins led to deposition of Fe-oxides and hydroxides, commonly filling fractures or replacing early-formed sulphide assemblages. The various vein types display classic epithermal textures including open space filling, banding, comb quartz and brecciation. The Ag-bearing minerals comprise pyrargyrite [Ag3(Sb,As)S3], argentotennantite [(Cu,Ag)10(Zn,Fe)2(Sn,As)4S13], polybasite-pearceite [(Ag,Cu)16(Sb,As)2S11], and acanthite [AgS2]; associated sulphides include galena, sphalerite, chalcopyrite, arsenopyrite and pyrite. In the main ore zone, base metal sulphides are commonly intergrown with the Ag-bearing sulfosalts. Analyses of galena show no significant silver values indicating that silver grades are exclusively associated with the Ag-bearing sulfosalts and sulphides. The distribution of the Sb/(Sb + As) ratios in the silver sulfosalts indicate that the ore forming fluid(s) was consistently antimony-rich during the Ag-rich ore deposition with no significant variation laterally, vertically, or along strike of the vein systems. However, Ag/(Ag + Cu) values in argentotennantite decrease along-strike from NE to SW and with depth. Compositions of argentotennantite + pyrargyrite + sphalerite indicate a primary depositional temperature around 325-350° C for the late phase of the Main-ore stage. Compositions of sphalerite also show an increasing trend in FeS (mol %) along strike of the deposit from NE to SW. The geometric relationship between the various structures, vein types, and the regional Miguel Auza fault zone suggest episodic reverse-sense reactivation of normal faults. It is argued that the structural evolution of the area, and, in particular, the Main-ore stage, provided transport pathways for metal-rich fluids and controlled the orientations of ore-bearing veins. Variations in mineral chemistry suggest that the rocks in the NE sector interacted with hotter fluids than in the SW part of the deposit.

  13. Calcretized Ferricretes Around the Jaisalmer Area, Thar Desert, India: Their Chemistry, Mineralogy, Micromorphology and Genesis

    OpenAIRE

    TIWARI, DESIKAN RAMAKRISHNAN & KRISHNA CHANDRA

    2006-01-01

    Ferricrete, an iron duricrust, caps Tertiary and Mesozoic rocks around Jaisalmer in the Indian desert. These ferricretes are associated with two distinct present-day landforms. The upper unit is a high-level dissected, rocky structural plain and the lower one a colluvial flat with soft ferricrete gravels. This study pertains to the first situation wherein field observations, micromorphological features and regolith chemistry suggest an in situ origin for the ferricretes, as in the case of the...

  14. The lateritic profile of Balkouin, Burkina Faso: Geochemistry, mineralogy and genesis

    Science.gov (United States)

    Giorgis, Ilaria; Bonetto, Sabrina; Giustetto, Roberto; Lawane, Abdou; Pantet, Anne; Rossetti, Piergiorgio; Thomassin, Jean-Hugues; Vinai, Raffaele

    2014-02-01

    This study reports on the geochemical and mineralogical characterization of a lateritic profile cropping out in the Balkouin area, Central Burkina Faso, aimed at obtaining a better understanding of the processes responsible for the formation of the laterite itself and the constraints to its development. The lateritic profile rests on a Paleoproterozoic basement mostly composed of granodioritic rocks related to the Eburnean magmatic cycle passing upwards to saprolite and consists of four main composite horizons (bottom to top): kaolinite and clay-rich horizons, mottled laterite and iron-rich duricrust. In order to achieve such a goal, a multi-disciplinary analytical approach was adopted, which includes inductively coupled plasma (ICP) atomic emission and mass spectrometries (ICP-AES and ICP-MS respectively), X-ray powder diffraction (XRPD), scanning electron microscopy with energy dispersive spectrometry (SEM-EDS) and micro-Raman spectroscopy.

  15. Red rover: inside the story of robotic space exploration, from genesis to the mars rover curiosity

    CERN Document Server

    Wiens, Roger

    2013-01-01

    In its eerie likeness to Earth, Mars has long captured our imaginations—both as a destination for humankind and as a possible home to extraterrestrial life. It is our twenty-first century New World; its explorers robots, shipped 350 million miles from Earth to uncover the distant planet’s secrets.Its most recent scout is Curiosity—a one-ton, Jeep-sized nuclear-powered space laboratory—which is now roving the Martian surface to determine whether the red planet has ever been physically capable of supporting life. In Red Rover, geochemist Roger Wiens, the principal investigator for the ChemCam laser instrument on the rover and veteran of numerous robotic NASA missions, tells the unlikely story of his involvement in sending sophisticated hardware into space, culminating in the Curiosity rover's amazing journey to Mars.In so doing, Wiens paints the portrait of one of the most exciting scientific stories of our time: the new era of robotic space exploration. Starting with NASA’s introduction of the Discovery...

  16. Negotiating supranational rules. The genesis of the International Atomic Energy Agency safeguards system

    Energy Technology Data Exchange (ETDEWEB)

    Forland, A.

    1997-12-31

    The object of this study is the evolution from 1954-56 up until the mid-1970s of the nuclear safeguards system administered by the International Atomic Energy Agency (IAEA) in Vienna. The main aim of the study is not to describe the IAEA safeguards system as such. The focus will be on analysing the arguments advanced in the various negotiations, and the main objective will be to single out the factors determining the result. In the course of the time span under study two international treaties were negotiated which were decisive for the development of international nuclear safeguards. These were the IAEA Stature (1956) and the Non-Proliferation Treaty (1968). The Statue as well as the NPT contain articles on international nuclear safeguards. These articles limit themselves to spelling out the safeguards principles. It was thus left to the IAEA Board of Governors to develop the safeguards procedures in detail. Two IAEA safeguards documents were negotiated between 1959 and 1965 in order to implement the safeguards article of the Statue. The safeguards requirements of the NPT were spelled out in a new model agreement in 1972. 58 refs.

  17. Negotiating supranational rules - The genesis of the International Atomic Energy Agency Safeguards System

    Energy Technology Data Exchange (ETDEWEB)

    Forland, Astrid

    1998-12-31

    The object of this thesis is the evolution from 1954-56 up until the mid 1970s of the nuclear safeguards system administered by the International Atomic Energy Agency (IAEA) in Vienna. The evolution is traced not through the practical implementation of the safeguards system, but through the various multilateral negotiations through which it was created. The focus is on analysing the arguments advanced in the various negotiations, and the main objective is to single out the factors determining the result. The discussion is organised into the following chapters: (1) The statute of the IAEA, (2) The IAEA 1961 safeguard document (INFCIRC/26), (3) The IAEA 1965 safeguards document (INFCIRC/66), (4) The non-proliferation treaty, (5) NPT safeguards. 92 refs.

  18. The age, nature and likely genesis of the Cambrian Khantaishir arc, Lake Zone, Mongolia

    Science.gov (United States)

    Janoušek, Vojtěch; Jiang, Yingde; Schulmann, Karel; Buriánek, David; Hanžl, Pavel; Lexa, Ondrej; Ganchuluun, Turbat; Battushig, Altanbaatar

    2014-05-01

    Recent discovery of the huge Cambrian arc in the Khantaishir Mountain Range (SE Mongolian Altai) suggests that the principal Neoproterozoic and Devonian-Carboniferous episodes of crustal growth in the Central Asian Orogenic Belt (CAOB) (Sengör et al. 1993) have to be revised. This probably the largest arc system known in the Mongolian tract of the CAOB is seemingly intrusive into the Neoproterozoic accretionary wedge (the Lake Zone) in the N and underthrust southwards below the Palaeozoic volcanosedimentary prism (Gobi Altai Zone). The arc shows a section from deep, ultramafic cumulates to shallower crustal levels of the magmatic system and thus provides an excellent opportunity to study this important period of crustal growth in the Mongolian CAOB. The magmatic rocks are intermediate to ultrabasic (SiO2 = 39.2-61.8 wt. %), rather primitive (mg# = 45-60) Amp-Bt tonalites to coarse-grained Amp gabbros and hornblendites. They are Na-rich (Na2O/K2O = 1.3-9.7 by wt.), exclusively metaluminous and mostly subalkaline, except for the ultrabasic types that enter the alkaline domain due to accumulation of Amp crystals. The P-T conditions calculated using the Amp thermobarometer of Ridolfi et al. (2010) show that the gabbro crystallized at 930-950 ° C and 0.36-0.43 GPa. The (normal-) calc-alkaline chemistry and characteristic trace-element enrichment in hydrous-fluid mobile large-ion lithophile elements (LILE: Rb, Ba, Th, U, K and Pb) over high-field strength elements (HFSE: Nb and Ta) confirm an origin within an igneous arc. The newly obtained LA ICP-MS zircon ages for three tonalites-diorites range between 516 ± 2 Ma and 494 ± 3 Ma. While zircons in two of them give high initial ɛHf values (+8 to +14), implying a derivation by (near) closed-system fractionation from little modified, depleted-mantle derived magmas, the third contains significantly different component (ɛHf = +3 to +6). The latter component may have come from a distinct, less depleted/metasomatized mantle domain or, more likely, originated by remelting of a juvenile metabasic crust, presumably by the advected heat from the voluminous mantle-derived melts. The single gabbro yielded two zircon populations, 521 ± 6 Ma (avg. 238U-206Pb age, 3 grains) and 538 ± 3 Ma (8 grains). The zircons contain both components distinguished in the more felsic samples (ɛHf = +4 to +13), compatible with the field evidence for the presence of several generations of the basic magmas, as well as magma mixing/mingling between contrasting magma batches. Taken together, our data provide an evidence for a Cambrian (c.520-495 Ma) magmatic-arc activity in the Khantaishir Range. The lack of significant zircon inheritance and rather primitive ɛHfvalues (all > +3) imply that the arc was not funded on mature continental crust. On the contrary, a key role was played by depleted-mantle derived magmas, perhaps with some recycling of a juvenile metabasic crust. Financial support: Grant Agency of the CR (P210/12/2205), Ministry of Education of the CR (LK11202) and Hong Kong Research Council (HKU705311P and HKU704712P). Ridolfi et al. 2010. Contrib. Mineral. Petrol. 160, 45-66. Sengör et al. 1993. Nature 364, 299-307.

  19. Social mechanisms of media institutions: The genesis of recipient’s preferences

    Directory of Open Access Journals (Sweden)

    V L Mouzykant

    2017-12-01

    Full Text Available Within the framework of sociology of media the author explains the behavior of target audiences in the nowadays media environment, analyzes the changing nature of the relationship between the sender and the recipient of the message. The article considers the social mechanisms of the contemporary media institutions and changes in media consumption preferences of different social strata under the growing influence of communication technologies. The author believes that the digitalization determines the audience’s need for explanation instead of just information. The virtual reality as a new communication platform becomes a common practice, and the audience becomes its passive participant demanding new ways of real-time access to information. The print media audience is gradually moving from constant reading of one or two mass editions to the study of a large number of specialized media. There is the same trend of the declining share of main television channels in advertising budgets due to the increasing share of specialized network channels. At the same time, advertising budgets are transferred to the mobile platforms for there is a growing need in ‘big data’ in real time due to the fast development of mobile electronic devices. Tablets and smartphones are attributes of the emerging media ecology that are gradually replacing television for digital generations prefer to watch the same TV content ‘outside’ the traditional TV environment.

  20. DIZZINESS OF ISCHEMIC GENESIS: DESCRIPTION OF VESTIBULAR DISORDERS AND POSSIBILITY OF THERAPY

    Directory of Open Access Journals (Sweden)

    N. S. Alekseeva

    2015-12-01

    Full Text Available Aim. To reveal the peculiarities of peripheral and central vestibular disorders in patients with mild dizziness in initial and reversible cerebrovascular diseases and estimate the efficacy of dizziness therapy with betahistine dihydrochloride (Betaserc, Solvay Pharma.Material and methods: 40 patients (all women with dizziness were studied. Neurological and otoneurological examination was done; central hemodynamics and number of vascular indices were analyzed. Therapy with Betaserc in daily dose of 48 mg was held during 2 months.Results. Dysfunction of both peripheral and central parts of vestibular analyzer was revealed in all patients. Most patients complained on diminished hearing, buzzing in ears and head, imbalance while walking. All patients mentioned the performance impairment, easy fatigability, change of mood. Therapy with Betaserc improved the condition of 97% patients with dizziness, the intensity of associated acoustic disturbances considerably reduced.Conclusion. Betaserc is an effective drug for dizziness therapy in patients with initial and reversible cerebrovascular diseases.

  1. Twenty-five years of the common market in coal, 1953--1978. [genesis and growth

    Energy Technology Data Exchange (ETDEWEB)

    1978-01-01

    Twenty-five years have passed since the European Coal and Steel commmunity was established. An attempt is made to show what economic integration is, what problems have arisen, and how the community has tried to overcome them. Three phases can be distinguished during the period under review--a first phase of growth in the coal industry between 1953 and 1957; a second phase marked by a plentiful supply of cheap hydrocarbons and a rapid reduction in coal output despite exceptional growth, linked with a parallel increase in overall energy requirements; and a third phase from 1973, marked by sharp price increases by the oil producing countries with repercussions on the world market in coal.

  2. Borges y Calvino: La genesis de la novela Si una noche de invierno un viajero

    Directory of Open Access Journals (Sweden)

    Tea Štoka

    2005-12-01

    Full Text Available El crítico italiano Cesare Segre1   adscribe la génesis de la novela de Calvino Si una noche de invierno un viajero al cuento de Borges Examen de la obra de Herbert Quain, que figura entre los trece cuentos de Ficciones (1944. En este cuento, Borges describe, analiza y comenta las novelas de Herbert Quain inventadas como si fueran obras literarias reales. Las emplaza al mismo nivel de realidad que las obras dramáticas de Shakespeare, las novelas de Henry James y Gustavo Flaubert.

  3. Those Were Some of the Hottest Days of My Life: The Genesis of SCOLT

    Science.gov (United States)

    Swanson, Pete

    2015-01-01

    The following article recounts the creation and development of the Southern Conference on Language Teaching (SCOLT) through the words of one of its founders, Dr. Herman Bostick. The article is not intended to tell the entire history of the founding of the organization, nor the full story of Dr. Bostick's contributions to the civil rights movement…

  4. Turism and Psychology studies: genesis of pleasure in classical Freudian psychoanalysis

    Directory of Open Access Journals (Sweden)

    Maximiliano Korstanje

    2009-01-01

    Full Text Available In this work we intend to demonstrate the different treatments which the Psychology has made about the pleasure as well as the contributions or limitations that the psychoanalysis demonstrates in the matter. The pleasure is configured like a discharge generated by the encounter between the instincts of life (Eros and of death (Thanatos in conjunction with the exogenous excitement. In consequence, the principle of the transfer explains the displacement (tourist like a form of psychic balance.

  5. Hot subluminous stars: On the Search for Chemical Signatures of their Genesis

    Science.gov (United States)

    Hirsch, Heiko Andreas

    2009-10-01

    This thesis deals with the hot subluminous stars of spectral class O. Although the name suggests otherwise, these stars are still 10 to 1000 times more luminous than the sun, they emit most of their radiation energy in the ultraviolet range. First stars of this type have been categorized in the 1950ies. Since they are blue objects like Quasars they often are discovered in surveys at high Galactic latitudes aiming at Quasars and other extragalactic objects. The hot subluminous stars can be divided into two classes, the subluminous O and subluminous B stars, or short sdO and sdB. The sdOs and sdBs play an important role in astronomy, as many old stellar populations, e.g. globular clusters and elliptical galaxies, have strong UV fluxes. UV bright regions often are "stellar nurseries", where new stars are born. Globular clusters and elliptical galaxies, however, do not experience star formation. This UV excess can be explained by population models that include the hot subluminous stars. Many sdB stars show short-period, multiperiodic light variations, which are due to radial and nonradial pulsations. Asteroseismology can explore the inner structure of stars and estimate e.g. the stellar mass, a variable that can only determine in very lucky circumstances (eclipsing binaries). These stars are also important for cosmology because they qualify as supernova Ia progenitors. The nature of the sdO stars is less well understood than that of their cooler and more numerous siblings, the sdBs. The connection of the sdBs to the horizontal branch is established for many years now, accordingly they are old helium core burning objects after their red giant phase. More precisely, they are on the extended horizontal branch (EHB), the hot end of the horizontal branch. EHB stars are characterized by a very low envelope mass, i.e. we see more or less directly the hot helium burning core. Strong mass loss in the RGB phase is regarded as responsible for this phenomenon, the exact mechanism, however, is still under debate. While the cooler sdBs can be analyzed with relatively simple LTE model atmospheres, the hot sdOs require much more sophisticated NLTE calculations. The large effort required for sdO analyses resulted in a relatively low number of paper on the subject, when compared with the numerous publications on sdB stars. Besides a few detailed studies of individuell objects, the ≈ 50 stars analyzed by Ströer et al. (2007) is the only extensive work on sdOs. They explained the helium poor sdOs as progeny of the sdB stars. But for the helium enriched sdOs, no definite statement about their evolutionary status could be found. In order to get a large sample of sdOs, this work made use of the Sloan Digital Sky Survey (SDSS), one of the most extensive photometric and spectroscopic surveys in astronomy. About 14000 spectra were classified by visual inspection by means of easily recognizable spectral features. We now have a large database with classificatons of hot stars. The majority of the spectra were classified as white dwarfs, among them a number of previously unknown magnetic white dwarfs. 1500 objects were identified as hot subluminous stars, about 200 of them are sdOs. We determined effective temperatures, surface gravities and atmospheric helium abundances for these objects. Two evolutionary scenarios remain valid options for the sdOs' origin: The merging of two helium white dwarfs and the delayed helium flash of a red giant star ("late hot flasher"). In the first scenario, two low mass white dwarfs in short period orbits lose orbital energy by radiation of gravitational waves. As their orbit shrinks, the less massive one will fill its Roche lobe and get disrupted and accreted on the companion. Unfortunately no detailed calculations of the explosive nucleosynthesis exist for this scenario. The late hot flashers are stars that do not experience the helium core flash until they leave their red giant phase and already evolve towards the white dwarfs. Miller Bertolami et al. (2008) published detailed theoretical calculations for this scenario. They predict a strong enrichment with carbon and in some cases with nitrogen by mixing processes. A differentiation between both scenarios was not possible so far, as we only determined helium abundances. The creation of new NLTE model atmospheres which include carbon and nitrogen enabled us to measure their abundances in three dozen sdOs. Effective temperatures did not change much with the application of the new models, but the surface gravity was found about 0.2 dex lower than in previous analyses. This provides a solution for a handful of stars that until now were situated below the helium main sequence, which would not allow stable helium core burning. On the other hand, the whole distribution is shifted towards lower gravities while the theoretical calculations predict an accumulation of stars at higher surface gravities, near the helium main sequence. The measured carbon abundances reveal a bimodal distribution: half of the objects has carbon enriched up to 10 times the solar value, a clear indication of 3α processed material mixed from the core into the envelope, the other half shows carbon strongly depleted. With some exceptions, nitrogen is above solar abundances, up to a factor of ten. Stars with very low carbon content cannot have experienced mixing of matter from the core into the envelope, only CNO-processed matter is exposed. Three stars with high carbon abundances are found that have a very low nitrogen content. These stars are not easily understood: matter from the core must have been brought into the envelope, but not the CNO-processed matter. A surprising correlation is found for the rotational velocites with abundances: nearly all stars with high carbon abundances also have high projected rotational velocities vrot sin i = 10 . . . 30 km s-1. Because the sdB stars are very slow rotating with vrot sin i < 10 km s-1 (unless spun up by tidal iteraction in close binary systems), this disqualifies any evolutionary connection between sdBs and the carbon rich sdOs. Those stars without carbon on the other hand show no significant rotational broadening in their line profiles. Altogether eight stars can be considered as compatible with having experienced a delayed helium flash. Those stars with high nitrogen abundances but only very little atmospheric carbon are not predicted by any late hot flasher calculation. They are considered candidates for the white dwarf merging scenario, which we cannot yet verify due to missing calculations. Another remaining problem are the three stars with high carbon, but very low nitrogen abundances. One possible explanation would be a very metal poor (halo) origin for these objects, which could be verified in the future by a quantitative analysis of the heavier metals. Alternatively the examinations of the kinematic properties of the stars could provide clues concerning their membership to the halo population.

  6. Biogenic catalysis in sulphide minerals' weathering processes and acid mine drainage genesis.

    Science.gov (United States)

    Kušnierová, Mária; Praščáková, Mária; Nowak, Anna K; Gorazda, Katarzyna; Wzorek, Zbigniew

    2014-01-01

    Bioleaching and biogenesis are the main outputs from a large group of environmental processes participating in the natural material cycle, used in raw materials processing. Bio-oxidation reactions are the main basis for bioleaching procedures, often participating in parallel leaching processes. During the leaching processes of polycomponent sulphide substrates, the factor of process selection also plays an important role, being in direct relation to the electric properties and galvanic effect occurring between the individual components of the leaching substrate. This work gives a summary of the results of a research focused on the possibilities of using biotechnological procedures for treatment of Slovak sulphide ores. The object of the research is extraction of valuable metals, undesirable admixtures and degradation of crystal lattice of sulphides for subsequent chemical leaching processing of precious metals. The results of experiments on the existence of biogenic processes in situ on waste dumps from exploitation containing residual sulphides are also presented. The processes result in acid mine drainage water generation. These waters are strongly mineralised (over 48 g/L) and of low pH; that is why they are very caustic. The arsenic content (2.558 mg/L) in outflowing waters from old mines is high and over the limits set by the law.

  7. Genesis and bifurcations of unstable periodic orbits in a jet flow

    International Nuclear Information System (INIS)

    Uleysky, M Yu; Budyansky, M V; Prants, S V

    2008-01-01

    We study the origin and bifurcations of typical classes of unstable periodic orbits in a jet flow that was introduced before as a kinematic model of chaotic advection, transport and mixing of passive scalars in meandering oceanic and atmospheric currents. A method to detect and locate the unstable periodic orbits and classify them by the origin and bifurcations is developed. We consider in detail period-1 and period-4 orbits playing an important role in chaotic advection. We introduce five classes of period-4 orbits: western and eastern ballistic ones, whose origin is associated with ballistic resonances of the fourth-order, rotational ones, associated with rotational resonances of the second and fourth orders and rotational-ballistic ones associated with a rotational-ballistic resonance. It is a new kind of unstable periodic orbits that may appear in a chaotic flow with jets and/or circulation cells. Varying the perturbation amplitude, we track out the origin and bifurcations of the orbits for each class

  8. Long-term soil productivity: genesis of the concept and principles behind the program

    Science.gov (United States)

    Robert F. Powers

    2006-01-01

    The capacity of a forest site to capture carbon and convert it into biomass defines fundamental site productivity. In the United States, the National Forest Management Act (NFMA) of 1976 mandates that this capacity must be protected on federally managed lands. Responding to NFMA, the USDA Forest Service began a soil-based monitoring program for its managed forests....

  9. Hermeneutics in identity formation: Paul’s use of Genesis in Galatians 4

    Directory of Open Access Journals (Sweden)

    Jeremy Punt

    2011-04-01

    Full Text Available Paul’s hermeneutics, in dealing with the scriptures and traditions of Israel and his concern for a specific identity for the communities he interacted with, require attention for the reciprocal, interrelationship between hermeneutics and identity in his letters. Paul’s quotations from and allusions to the scriptures of Israel but also his argument which was a re-interpretation of the traditions of Israel, functions in Galatians 4:21–5:1 at one level as counter-argument to the position of his opponents in Galatia but, at another deeper level, also as a forceful attempt to (reestablish and reinforce the identity of the community of followers of Jesus. His appropriation of the scriptures, his revisionist interpretation of the Abraham narrative and in particular his construal of its lasting implications provided the interpretative map on which Paul plotted an emerging ‘Christian’ identity. But, reciprocally, Paul’s sense of a new or renewed identity in Christ also determined the contours of his hermeneutics.

  10. Source constraints on the genesis of Danubian granites in the South Carpathians Alpine Belt (Romania)

    Science.gov (United States)

    Duchesne, Jean-Clair; Laurent, Oscar; Gerdes, Axel; Bonin, Bernard; Liégeois, Jean-Paul; Tatu, Mihai; Berza, Tudor

    2017-12-01

    The pre-Alpine basement of the Lower Danubian nappes in the South Carpathians is made up of two Precambrian terranes (Drăgşan and Lainici-Păiuş) that were intruded by Pan-African/Cadomian and Variscan granitoid massifs. We focus on the major and trace element geochemistry (1) in the Drăgşan terrane, of the Variscan Retezat and Parâng intrusions; (2) in the Lainici-Păiuş terrane, of the Variscan Furcǎtura, Petreanu and Frumosu intrusions and of the Pan-African Vârful Pietrii, Şuşiţa and Olteţ granites and granitic leucosomes of migmatites; and (3) in the Upper Danubian nappes basement, of the Variscan Muntele Mic, Sfârdin, Cherbelezu and Ogradena intrusions. For each intrusion, in which a range of composition is observed, we decipher the differentiation mechanisms (fractional crystallization, hybridization, melt laden with restite minerals, etc.) in order to define the parental liquid compositions. The latter are calc-alkaline to alkali-calcic (except Olteţ that is calcic) and medium to high-K in composition. With [La/Yb]N > 10 and Sr/Y > 15, most melts display the so-called "continental adakite" affinities. The parental melt compositions are compared with experimental data to determine the melting conditions and the nature of the source rock. When the P-T conditions can be estimated, the temperatures range between 850 °C and 875 °C and the pressure between 5 and 15 kbar regardless of the ages of the granites and the terrane in which they have intruded. The source rock composition is dominated by a variety of mafic igneous compositions or metasediments rich in volcanic components. Clay-rich (pelitic) protoliths have not been identified. We confirm a Variscan age (c. 300 Ma) for the Frumosu intrusion granite and inherited Precambrian ages (c. 1.7-1.9 and 2.6-2.9 Ga) for the Motru dyke swarm. Thus, both Drăgşan and Lainici-Păiuş together with the Upper Danubian basement terranes were affected by Variscan post-collisional granitic plutonism. In the South Carpathians, both Pan-African and Variscan granites were generated in a crust thickened by stacking of terranes. The source of the Pan-African granites in Lainici-Păiuş is different from that of the Variscan granites (from Lainici-Păiuş and Drăgşan terranes and from the Upper Danubian nappe basement), but all these sources were notably depleted in metapelite component.

  11. Paranormal Medicine: Mind Over Matter in the Genesis and Cure of Disease

    Science.gov (United States)

    Eisenberg, Howard

    1977-01-01

    Paranormal medicine refers to the application of mental and quasiphysical processes that are not presently understood and/or recognized by orthodox science, in the diagnosis and treatment of disease. Current research shows that the ‘mind over matter’ theory can be applied successfully in treating several ‘physical’ conditions. PMID:20469283

  12. The genesis of the “giusto processo” constitutional reform in Italy

    Directory of Open Access Journals (Sweden)

    Paolo Ferrua

    2017-06-01

    Full Text Available This paper analyzes the complicated scenario that, starting with the promulgation of the current Italian criminal procedure code, in 1999 resulted in the constitutional reform of the "giusto processo". Inspired by an accusatory logic, the 1988 Code had introduced the contradictory "golden rule" in the formation of evidence, establishing the irrelevance of declarations secretly collected by the preliminary investigation actors. Unhappily received by the majority of the judiciary, the accusatory principles were suppressed in 1992 by the "inquisitorial revolution" caused by three constitutional court decisions (No. 24, 254, 255. Assuming that the contradictory in evidence production violates the search for the truth, the Constitutional Court has demolished the "golden rule," attributing probative value to all (or almost statements unilaterally collected in the preliminary investigation by the prosecutor or the police. In fact, the mistake of the Constitutional Court was not figuring that the function of the criminal process is the revelation of the truth, which must be sought by any process that aspire the confidence of the citizens. The mistake was actually considering the contradictory as an obstacle to the pursuit of truth, causing an unfortunate opposition between two values that should be closely related. Essential to the cognitive function of the process is, in fact, the contradictory, the method which, as science clarifies, consists in subjecting the hypotheses to be proved to the most severe attempts of confrontation and falsification; while, on the other hand, it seems entirely reasonable to distrust what has been formed in secrecy, and especially the declarations that inevitably take preference to influence those who, in a position of authority, have unilaterally collected them. A reticent and partial attempt to recover the contradictory was later operated by Law 267 of 1997, which denied the probative value of previous statements on the responsibility of other co-defendants who afterwards exercised their right to silence. The law, however, even by reason of its objective inconsistencies, has been declared illegitimate once more by the Constitutional Court, with sentence 361 of 1998. But this time, together with the Union of Criminal Chambers, also appear the political forces, wounded by the censorship of a law that had been adopted almost unanimously shortly before. After that, promptly was approved the constitutional reform of the "giusto processo" (Constitutional Law No. 2 of November 23, 1999, which affirms that "criminal proceedings are regulated by the contradictory principle in the production of evidence (Article 111, paragraph 4, Const.

  13. Factors Affecting Infants’ Manual Search for Occluded Objects and the Genesis of Object Permanence

    Science.gov (United States)

    Moore, M. Keith; Meltzoff, Andrew N.

    2009-01-01

    Two experiments systematically examined factors that influence infants’ manual search for hidden objects (N = 96). Experiment 1 used a new procedure to assess infants’ search for partially versus totally occluded objects. Results showed that 8.75-month-old infants solved partial occlusions by removing the occluder and uncovering the object, but these same infants failed to use this skill on total occlusions. Experiment 2 used sound-producing objects to provide a perceptual clue to the objects’ hidden location. Sound clues significantly increased the success rate on total occlusions for 10-month-olds, but not for 8.75-month-olds. An identity development account is offered for why infants succeed on partial occlusions earlier than total occlusions and why sound helps only the older infants. We propose a mechanism for how infants use object identity as a basis for developing a notion of permanence. Implications are drawn for understanding the dissociation between looking-time and search assessments of object permanence. PMID:18036668

  14. Factors affecting infants' manual search for occluded objects and the genesis of object permanence.

    Science.gov (United States)

    Moore, M Keith; Meltzoff, Andrew N

    2008-04-01

    Two experiments systematically examined factors that influence infants' manual search for hidden objects (N=96). Experiment 1 used a new procedure to assess infants' search for partially versus totally occluded objects. Results showed that 8.75-month-old infants solved partial occlusions by removing the occluder and uncovering the object, but these same infants failed to use this skill on total occlusions. Experiment 2 used sound-producing objects to provide a perceptual clue to the objects' hidden location. Sound clues significantly increased the success rate on total occlusions for 10-month-olds, but not for 8.75-month-olds. An identity development account is offered for why infants succeed on partial occlusions earlier than total occlusions and why sound helps only the older infants. We propose a mechanism for how infants use object identity as a basis for developing a notion of permanence. Implications are drawn for understanding the dissociation between looking time and search assessments of object permanence.

  15. Shale oil. I. Genesis of oil shales and its relation to petroleum and other fuels

    Energy Technology Data Exchange (ETDEWEB)

    McKee, R H; Manning, P D.V.

    1927-01-01

    Oil-shale kerogen originated from resinous vegetation residues of past eras, whereas well petroleum was formed from oil shales by pressure and mild heat. Petroleum migrated to its present reservoir from neighboring oil-shale deposits, leaving a residue of black bituminous shales. The high carbon dioxide content of gases present in petroleum wells originated from kerogen, as it gives off carbon dioxide gas before producing soluble oil or bitumen.

  16. Geology and Isotope Systematics of the Jianchaling Au Deposit, Shaanxi Province, China: Implications for Mineral Genesis

    Directory of Open Access Journals (Sweden)

    Su-Wei Yue

    2018-04-01

    Full Text Available The giant Jianchaling Au (52 t Au deposit is located in the Mian-Lue-Yang Terrane in the southern part of the Qinling Orogen of central China and is hosted by metamorphosed carbonate rocks of the Late Neoproterozoic Duantouya Formation. The deposit consists of multiple generations of mineralised quartz(-carbonate veins in WNW-trending extensional ductile-brittle shear zones. Based on the mineral assemblages and cross-cutting relationships between the quartz(-carbonate veins, the paragenesis is characterised by an early coarse-grained pyrite-pyrrhotite-pentlandite-dolomite-quartz assemblage (I, followed by pyrite-sphalerite-galena-carbonate-arsenopyrite-fuchsite-carbonate-quartz containing gold (II, and fine-grained pyrite-dolomite-calcite-quartz-realgar (As2S2-orpiment (As2S3 (III. The H-O-C isotope systematics for the three vein sets indicate that the mineralising fluid is probably sourced from the metamorphic dehydration of carbonate rocks in the Duantouya Formation, and gradually mixed with meteoric water during the emplacement of the third vein set. The δ34S values for sulfides (6.3–16.6‰ from the second auriferous vein set are greater than zero, indicating sulfates reduction from the Neoproterozoic metamorphic rocks (Duantouya Fm. The (206Pb/204Pbi ratios from pyrite (17.521–18.477 from each of the vein sets overlap those of the ultramafic rocks (18.324–18.717 and the Bikou Group (17.399–18.417, indicating that the units are possible sources for the sulfides in the mineralisation. Both εNd(t and Isr(t of sulfide overlap with the meta-ultramafic field and Duantouya formation and dominated with mature Sr-Nd character, which indicated that the Duantouya may play an important role during the ore formation and there may exist a minor ultramafic source that is involved in the ore fluid. The S-Pb-Sr-Nd isotopic ratios are closely related to those of the Bikou Group and Duantouya Formation, which indicates that the mineralised fluid has interacted with both units. Combining the previously published data with data from this study on the mineralised area, we surmise that Jianchaling is characteristic of an orogenic-type gold deposit related to the Triassic Qinling Orogeny associated with continental collision.

  17. "Mature Regionalism" and the Genesis of "Functional Projects": "Educational Regionalism" in Small (and Micro-States)

    Science.gov (United States)

    Jules, Tavis D.

    2017-01-01

    This article advances that the movement towards "deeper" Caribbean integration has generated a shift from "immature" regionalism to a "mature" form of regionalism. Thus, mature regionalism, a new governance mechanism, in regulating the institutional and legal framework of Caribbean Single Market and Economy is…

  18. The genesis of Kurišková U-Mo ore deposit

    International Nuclear Information System (INIS)

    Demko, R.; Biroň, A.; Novotný, L.; Bartalský, B.

    2014-01-01

    The U-Mo ores of the known uranium deposit Kurišková located in the Huta volcano-sedimentary complex (HVC) of lower Permian age belongs to the Petrova Hora Formation of the North-Gemeric tectonic unit (Western Carpathians). The HVC is built up by volcanic rocks of bimodal basalt-rhyolite association, intercalated with sandstones, mudstones and claystones. Based on the sedimentary facies reconstruction, it is supposed paleoenvironment of seasonally flooded shallow lakes of continental fluvial plain with transition to estuaries and shallow marine facies of continental shelf in the upper part of HVC.

  19. Genesis of Spodic Material underneath Peat Bogs in a Danish Wetland

    DEFF Research Database (Denmark)

    Kristiansen, Søren Munch; Dalsgaard, Kristian; Thomsen, Ingrid Kaag

    2010-01-01

    illuviation under a fluctuating water table, or (ii) degradation of a former Fe-rich, well-drained spodic horizon. Methods included soil surveys, wet chemical analyses, micromorphology, pollen analysis, and radiocarbon dating of soil organic matter (OM) fractions. Aquods, and soil material with spodic...... features, were exclusively found in sandy material at the margins of or underneath sphagnum peat bogs, whereas Inceptisols were found on well-drained sandy deposits only. Aluminum content was very high and Fe low in spodic materials with ortstein properties. Solid-state 13C nuclear magnetic resonance (NMR....... Radiocarbon ages of bulk soil C in the spodic horizons had mean residence times of 4500 to 4400 yr. Accordingly, the spodic B horizon was probably formed by strong in situ illuviation of Al-OM complexes before the sphagnum peat bog formation. This suggests that spodic material formation and thus strong C...

  20. Genesis of hydrothermal alterations using stable isotope geochemistry in Takestan area (Tarom zone

    Directory of Open Access Journals (Sweden)

    Batool Taghipou

    2015-12-01

    Full Text Available Hydrothermal alteration processes are extensively took place on volcanic and pyroclstics of Takestan area. Existence of abundant, deep fracturing and subvolcanic intrusions are enhanced extend hydrothermal alteration zones. The following alteration zones are determined: propylitic, argillic, advanced argillic and sillicic. There are outcropped and widespread in different size and limit. Formation of siliceous sinter, silicified tuffs with preserved primary sedimentary layering including pure mineralized alunite patches are most outstanding. Quartz, sussoritic plagioclase, chlorite, sericite and alunite are main mineral constituents in the volcanics. On the basis of geochemical data volcanic rocks are rhyolite, dacite, andesite, andesitic-basalt and basalt in composition. Acid-sulfate zone is the type of alteration in Tarom area and alunite is an index mineral of this zone. Results of 18O, D and 34S stable isotope geochemistry on altered minerals (muscovite, kaolinite and alunite, revealed that alteration fluids are magmatic in origin.

  1. Genesis of the Abu Marawat gold deposit, central Eastern Desert of Egypt

    Science.gov (United States)

    Zoheir, Basem A.; Akawy, Ahmed

    2010-06-01

    Gold mineralisation at the Abu Marawat mine, central Eastern Desert of Egypt, is related to a system of massive and sheared, milky quartz veins cutting a sequence of Neoproterozoic island arc metavolcanic/volcaniclastic rocks and related banded iron formation (BIF). Sulphide-bearing quartz veins and related hydrothermal breccia bodies display a range of textures including sheared, boudinaged and recrystallised quartz, open space filling and microbreccia. These variable textures imply a complex history of crack-seal mechanism characterising the relation between mineral deposition and a major N-S-trending shear zone, during a late brittle-ductile deformation event which affected the area at about 550 Ma. Gold-base metal mineralisation is associated with brecciation and fracturing of the iron ore bands, close to silicified shears and related quartz veins. The auriferous quartz lodes are characterised by the occurrence of visible pyrite-chalcopyrite ± pyrrhotite ± sphalerite ± galena mineralisation. Gold is refractory in pyrite and chalcopyrite, but rare visible gold/electrum and telluride specks were observed in a few samples. Hydrothermal alteration includes pervasive silicification, pyritisation, sericitisation, carbonatisation confined to a delicate set of veins and altered shears, and a more widespread propylitic alteration assemblage (quartz + chlorite + pyrite + calcite ± epidote). Fluid inclusion petrography and microthermometric studies suggest heterogeneous trapping of a low-salinity (1.4-6.7 wt.% eq. NaCl) aqueous solution and a carbonic fluid. Evidence for fluid immiscibility during ore formation includes variable liquid/vapour ratios in inclusions along individual trails and bulk inclusion homogenisation into liquid and occasionally to vapour at comparable temperatures. The trapping conditions of intragranular aqueous-carbonic inclusions approximate 264-378 °C at 700-1300 bar. Similar temperature estimates have been obtained from Al-in-chlorite geothermometry of chlorite associated with sulphides in the mineralised quartz veins. Fracturing enhanced fluid circulation through the wallrock and related BIF, allowing reaction of the S-bearing ore fluid with iron oxides. This caused pyrite formation and concomitant Au precipitation, enhanced by fluid immiscibility as H 2S partitioned preferentially into the carbonic phase. The ore fluids may have originated from granitoid intrusions (likely the post-Hammamat felsites, whereas gold and base metals might have been leached from the Abu Marawat basic metavolcanics.

  2. On the genesis of the uranium occurrence in the carboniferous sediments, wadi Intahahah area, southwest Libya

    International Nuclear Information System (INIS)

    Assaf, H.S.

    1988-01-01

    In the course of covering the southwestern part of Libya by a systematic airborne radiometric survey, a significant group of anomalies was detected in the carboniferous sediments. Ground verification of these anomalies disclosed the confinement of these anomalies to the limestone and sandstone beds of the Assedjefar Formation assigned to visean-namurian age. Uranium content as much as 1000 PPm was detected. The strong lithologic control of these uranium mineralizations together with the lack of evidences of hydrothermal activity implies an intrinsic source for the uranium. The uranium, most likely, was transported and introduced into the sediments, by geochemically active groundwater, during their deposition. Uranium, from this solution, could have been adsorbed onto organic matter or clay minerals

  3. Genesis of multipeaked waves of the esophagus: repetitive contractions or motion artifact?

    Science.gov (United States)

    Sampath, Neha J; Bhargava, Valmik; Mittal, Ravinder K

    2010-06-01

    Multipeaked waves (MPW) in the distal esophagus occur frequently in patients with esophageal spastic motor disorders and diabetes mellitus and are thought to represent repetitive esophageal contractions. We aimed to investigate whether the relative motion between a stationary pressure sensor and contracted peristaltic esophageal segment that moves with respiration leads to the formation of MPW. We mathematically modeled the effect of relative movement between a moving pressure segment and a fixed pressure sensor on the pressure waveform morphology. We conducted retrospective analysis of 100 swallow-induced esophageal contractions in 10 patients, who demonstrated >30% MPW on high-resolution manometry (HRM) during standardized swallows. Finally, using HRM, we determined the effects of suspended breathing and hyperventilation on the waveform morphology in 10 patients prospectively. Modeling revealed that relative movement between a stationary pressure sensor and a moving contracted segment, contraction duration, contraction amplitude, respiratory frequency, and depth of respiration affects the waveform morphology. Retrospective analysis demonstrated a close temporal association with the onset of second and subsequent contractions in MPW with respiratory phase reversals. Numbers of peaks in MPW and respiratory phase reversals were closely related to the duration of contraction. In the prospective study, suspended breathing and hyperventilation resulted in a significant decrease and increase in the MPW frequency as well as the number of peaks within MPW respectively. We conclude that MPW observed during clinical motility studies are not indicative of repetitive esophageal contraction; rather they represent respiration-related movement of the contracted esophageal segment in relation to the stationary pressure sensor.

  4. The role of coronary microvascular dysfunction in the genesis of cardiovascular diseases

    International Nuclear Information System (INIS)

    Parodi, O.; Sambuceti, G.

    1996-01-01

    Using PET, myocardial perfusion abnormalities secondary to microvascular disorders have beeen investigated in arterial hypertension (AH), dilated and hypertrophic cardiomyopathy (CM), as well as in ischemic heart disease (CAD). In AH, regional perfusion at rest is within the normal range, while the coronary reserve and flow response to increase in metabolic demand are blunted. Both dilated and hypertrophic CM demonstrate abnormal vasodilaing capability, wich as bee schown to be presented in the subclinical form of dilated DM; the reduction of coronary reserve is not related to the presence and extent of the hemodynamic impairment in dilated CM, and involved also nonhypertropied myocardium in asymmetric hypertropic CM. These finding indicate a primary involvement of coronary microcirculation in non advanced forms of dilated and hypertrophic CM. Finally, in patients with CAD, myocardia teritories supplied by angiographically normal coronary arteries schow abnormal coronary reserve and flow during pacing, tachycardia, indicating that, even in absence of epicardial coronary artery obstruction, microcirculation is impaired in subject with coronary atherosclerosis. this abnormally can smooth perfusion differences, between control andd jeopardized regions. Although the agreement with the angiographic documantation of coronary artery disease has been frequently considered to characterize the diagnostic reliability of these techiques, the evaluation of myocardial perfusion provides an independent tool for the functional assessment of patient with heart disease. The possibility of obtain measurement of regional myocardial blood flow, provided by positron emission thermography, helps to identify the mechanisms affecting flow regulation in the myocardium. This tool thus provides a new rationale for the application of perfusion imaging, to obtain a more precise characterization of these patients, beyond the agreement with the morphological angiographic picture

  5. Geochemistry and genesis of apatite bearing Fe oxide Dizdaj deposit, SE Zanjan

    Directory of Open Access Journals (Sweden)

    Ghasem Nabatian

    2009-09-01

    Full Text Available Sorkheh-Dizaj apatite-iron oxide deposit is located 32 km southeast of Zanjan. The area is situated within the Tarom subzone of Western Alborz-Azarbaijan structural zone. The oldest units at the Sorkheh-Dizaj area are Eocene trachyte, trachyandesite, olivine basalt and volcanoclastic brecciate tuff and lapilli tuff which intruded by a quartz-monzonite, monzonite and granite subvolcanic pluton of Upper Eocene- Early Oligocene age. Subvolcanic plutonic rocks in the area show characteristics of the I-type granites. Magmatism of the area is of synorogenic to postorogenic related to magmatic arc environments. Mineralization at the area is divided into three main zones (A, B and C that all of which are located in the host subvolcanic pluton. These three zones are similar in terms of host rock, mineralogy, alteration, structure, texture and metal content. Mineralization in the volcanic rocks occurs as veins similar to those in three main zones, but less abundant. Geometry of the ore bodies is of vein type and their textures are stockwork, massive, banded, brecciate and vein-veinlet. The most important minerals at Sorkheh-Dizaj deposit are magnetite (low Ti and apatite that associated with them minor sulfide minerals such as chalcopyrite, bornite and pyrite. Minerals such as ilmenite, spinel (titanium magnetite, galena and sphalerite occur in low contents. The supergene minerals like chalcocite, malachite, azurite, covellite, hematite and goethite have been formed due to weathering and supergene processes. The main alterations at the deposit are K-feldspar metasomatism, actinolitization, argillic, sericitization, silicification, tourmalinization, and chlorite-epidotic. Rare earth elements (REE studies demonstrate that the deposit is more enriched in LREE than in HREE. The REE patterns in the apatite, magnetite and host rocks are similar suggesting a magmatic relationship. The REE contents of the apatites are higher than those of the host rocks and magnetites. Fluid inclusion studies were conducted on two generations of apatite in the deposit. Based on the studies, the temperature and salinity of the first generation apatites are higher than those for the second generation apatites. The most important characteristics of the Sorkheh-Dizaj iron-oxide apatite deposit indicated magmatic Fe-P-REE-rich fluids source for the mineralization. Comparison of the most important characteristics of the Sorkheh-Dizaj iron-oxide apatite deposit (including tectonic setting, host rock, mineralogy, alteration, structure and texture and geochemistry with those of various types of iron mineralization in the world suggest that Sorkheh-Dizaj iron-oxide apatite deposit shows the most similarity with the Kiruna type iron-oxide apatite deposits classified as a subgroup of hydrothermal Iron Oxide Copper Gold (IOCG deposits.

  6. Geochemical characteristics and genesis of Baiyun pluton in southern Zhuguangshan mountain

    International Nuclear Information System (INIS)

    Zhang Shanguo; Huang Guolong; Fu Shuncheng; Wang Xiaodong; Xu Lili; Shen Weizhou

    2011-01-01

    Located in the east-central of the southern Zhuguangshan complex pluton, Baiyun pluton is an important uranium producing pluton. In lithology, it is coarse grain black mica granite. In major elements, the pluton is with rich silicon (SiO 2 average for 73.47%), rich aluminum (A/CNK value average 1.09) and high ratio of K 2 O/Na 2 O (average for 1.99). It is rich in large-ion trace elements Rb, Th, but poor in Ba, Sr, Ti, Nb, Ta, P. Rock samples have high Rb/Sr (average for 6.22) and Rb/ Nb ratio (average for 1.447), and rich uranium (average for 9.04 x 10 -6 ) which can act as the source for the formation of uranium deposit. In REE chemistry, the pluton is rich in LREE and relatively high fractionation between LREE and HREE, and bear the right-wing-type distribution pattern with obviously Eu depletion. In Isotopic chemistry,the pluton has low ε Nd (t) value(average for -10.6), high ( 87 Sr/ 86 Sr) i value (average for 0.71688), and old Nd mode age (1865∼1874 Ma). These characteristics consistently show that Baiyun pluton belongs to typical crustal source granite type and formed in an extensional tectonic environment shortly after the collision between South China and Indo-China plate from partial melting of argillaceous rocks in the middle-lower crust due to the comprehensive action of the decompression, water-prodution and mantle upwelling induced by crust stretching and thinning. (authors)

  7. 76 FR 73748 - Genesis Capital, LLC and Northern Lights Fund Trust; Notice of Application

    Science.gov (United States)

    2011-11-29

    ... the best interests of the Fund and its shareholders, and does not involve a conflict of interest from... them to enter into and materially amend subadvisory agreements without shareholder approval. Applicants... orders a hearing. Interested persons may request a hearing by writing to the Commission's Secretary and...

  8. Review of uranium in the Jordanian phosphorites: distribution genesis and industry

    International Nuclear Information System (INIS)

    Abed, A. M.

    2012-01-01

    Phosphorites are well-known, world wide, to accommodate a substantial amount of U relative to other sedimentary rocks. This is due a great extent to the crystal structure of apatite (carbonate flour apatite, flacitran) where U substitutes Ca phosphor ties from in shallow marine environments through the accumulation of planktonic follies debris on the sea floor in areas characterized by upwelling currents. Once the organic-rich sediments are buried below the sea floor and the organic matter is decomposed PO 4 is released to the interstitial solutions. These PO 4 -rich solutions either precipitate phosphorites directly (authigenic) or the solution react with pre existing sediments and tran form them to phosphorites (early decanting). The Jordanian deposits are dominantly of the former type. Consequently, phosphorites are also well known to be associated with high percentage of organic matter which makes them a good source rock for petroleum. In Jordan, phosphorites are wide spread from its extreme N W to the Se. Uranium contents are not the same in each locality. It is not also the same in each bed in the same locality. In Al-Kora Basin N W Jordan, U ranges between 60-379 ppm (parts per million or g/ton) with an average of 153 ppm. In Ruseifa, just east of Amman, the range is 132-195 ppm and average of 123 ppm.Central Jordan phosphorites (Al-Abiad and Al-Hasa) have a lower U%. The range is 34-190 ppm with average of 105 ppm. Eshidiyya Basin has a much less U. concentration. The range is 7-125 ppm with an average of 70 ppm. However, a recent work on the uppermost phosphorite horizon, the Ao, in Eshidiyya Basin proved the presence of a 3 m thick bed with 242 ppm U. furthermore, certain phosphorite horizons are known to have much more than the average U in that locality; e.g. in Al-kora Basin, the average U is 153 ppm while certain horizons have up to 379 ppm U, the uppermost bed in Ruseifa has up to 195 ppm while the average is 123 ppm, and in Eshidiyya the Ao has 242 ppm while the average of the lower horizon (A1-3) average is 70 ppm. Obviously, if the U is to be extracted from the phosphorite, the horizons with higher concentraction s of U should be explored and used. Uranium sticks to flacitran in its behavior from precipitin in the marine environment, through mining and beneficiation, and the fertilizer industry. 1) there is a significant high correlation coe relation between Ca O and P 2 O 5 in the hundreds of samples analyzed. 2) Fines (clays) produced when washing the ore have very little U and consequently, washing water for the last 45 years has not contaminated groundwater with U in central Jordan. 3) Uranium is concentrated in the phosphoric acid then into diammonium phosphate (Dap) in the fertilizer industry and not in the phosphogypsum. (author).

  9. The genesis and isotopic composition of carbonates associated with some Permian Australian coals

    International Nuclear Information System (INIS)

    Gould, K.W.; Smith, J.W.

    1979-01-01

    Siderite and calcite are the two forms of carbonate commonly associated with Permian Australian coals. The former occurs as disseminated spherulites and is a product of the early post-depositional environment. Isotopic measurements show that the CO 2 fixed as siderite did not result from the direct oxidation of photosynthetically derived materials, but rather from the anaerobic fermentation of these. The higher concentrations of calcite are generally found towards the roofs of coal seams and are characterized by isotopic enrichments to delta 13 C values of +25% PDB. Isotopic exchange between CO 2 and CH 4 within the coal seam is postulated as the mechanism which leads to the formation of isotopically heavy CO 2 . At sites along the seam margins where the CO 2 escapes, interaction with circulating metal ions or preexisting calcite results in the deposition of ''heavy'' calcite. With increasing alteration of coal by thermal metamorphism, the 13 C content of calcites and finally siderites decreases so that it more nearly approaches that of the associated coal. (Auth.)

  10. The aged brain: genesis and fate of residual progenitor cells in the subventricular zone

    Directory of Open Access Journals (Sweden)

    Vivian eCapilla-Gonzalez

    2015-09-01

    Full Text Available Neural stem cells persist in the adult mammalian brain through life. The subventricular zone is the largest source of stem cells in the nervous system, and continuously generates new neuronal and glial cells involved in brain regeneration. During aging, the germinal potential of the subventricular zone suffers a widespread decline, but the causes of this turn down are not fully understood. This review provides a compilation of the current knowledge about the age-related changes in the neural stem cell population, as well as the fate of the newly generated cells in the aged brain. It is known that the neurogenic capacity is clearly disrupted during aging, while the production of oligodendroglial cells is not compromised. Interestingly, the human brain seems to primarily preserve the ability to produce new oligodendrocytes instead of neurons, which could be related to the development of neurological disorders. Further studies in this matter are required to improve our understanding and the current strategies for fighting neurological diseases associated with senescence.

  11. [Regularities of the refractive genesis of school myopia and criteria for its prediction].

    Science.gov (United States)

    Onufriĭchuk, O N; Rozenblium, Iu Z

    2007-01-01

    The paper provides the data of a 2-year monitoring of ocular refraction in 327 consecutive 10-14-year-old schoolchildren (654 eyes) unrandomized under natural conditions and cycloplegia. The authors studied whether there was an association of refraction and its changes with absolute and relative accommodation, habitual accommodation tonicity, the length of the anteroposterior optic axis, and the presence of pseudomyopathy and astigmatism. Over 2 years, myopia occurred in 15.4% of the eyes, its degree increased from -0.88 (-1.37/-0.50) to -1.25 (-2.31/-0.62) diopters. Criteria for myopia prediction were identified. These included a relative accommodation reserve of less than 2.5 diopters, an anteroposterior optic axis length of more than 24.33 mm, a habitual accommodation tonicity of less than + 0.41 diopters, the presence of pseudomyopia (77.8% of cases), reversed astigmatism and underlying emmetropia. A mathematical model was constructed for prediction of myopia, the proportion of its correct prediction being 90.4%, which makes it possible to recommend for clinical application.

  12. Petrological Characteristics and Genesis of the Central Indian Ocean Basin Basalts

    Digital Repository Service at National Institute of Oceanography (India)

    Das, P.; Iyer, S.D.; Hazra, S.

    -532. Fornari, D. J., Perfit, M. R., Malahoff, A., Embly, R., 1983. Geochemical studies of abyssal lavas recovered by DSRV Alvin from Eastern Galapagos Rift, Inca Transform and Ecuador Rift. 1: major element variations in natural glasses and spatial...

  13. Genesis idea of the superman in european philosophy: concept Friedrich Nietzsche

    Directory of Open Access Journals (Sweden)

    A. Y. Somov

    2015-03-01

    Full Text Available The article is dedicated to the concept of Nietzsche superman in the context of development of the idea of European philosophy superman. Based on a study of scientific literature it was proved that Nietzsche was the first in European philosophy who has attempted to move away from its classical forms, creating a special type of superman, the values of which were creative, spiritual self, the victory over himself and the will to develop and adopt values, that multiply the power of life. It can be stated that superman Friedrich Nietzsche – a man who does not exist yet, and when it appears – is unknown. Initial characterization of superman Nietzsche is the power and the will who oppose «reasonableness» that seeks to bring originality to all acts of consciousness and identity. In superman should be personal development, their personal view of the world and its way. The main feature of the superman must be spiritual creativity, the total concentration of the will to power, that is able to completely control the superman himself: to know precisely aspiration, desire and how he organizes his way to the goal.

  14. The genesis of NRX - first stop on the road to CANDU

    Energy Technology Data Exchange (ETDEWEB)

    Arsenault, J.E.

    2015-12-15

    The CANDU (Canada Deuterium Uranium) reactor family is traceable to World War Two and to certain principal players. They gave Canada an early entry into the world of practical nuclear energy with the NRX (National Research Experimental) reactor, developed under the auspices of the ABC (America, Britain, Canada) countries. The principal players on the NRX project were, in alphabetical order: James Chadwick, C.D. Howe, Leslie R. Groves and C-J. Mackenzie. Their careers up to about 1940 are outlined in Section 10. (author)

  15. Occurrence and genesis of Quaternary microbialitic tufa at Hammam Al Ali, Oman

    Science.gov (United States)

    Khalaf, Fikry I.

    2017-05-01

    Remnants of late Quaternary microbialitic tufa occurs within a shallow depression in the Hammam Al Ali hot spring area, which is located approximately 14.5 km to the southwest of Muscat, Oman. The tufa precipitated from hot spring water supersaturated with respect to calcium carbonate and is mostly of a porous phytogenic type, with occasional detrital and stromatolitic types. Microscopic and nanoscopic examination revealed that the tufa deposits developed through two successive processes of calcite precipitation, biotic and abiotic, preceded by limited precipitation of unstable aragonite. It is suggested that biologically mediated precipitation results in the construction of incomplete skeletal calcite crystals. The latter provide a base for classical physiochemical precipitation and, eventually, the development of complete sparry calcite crystals. The initiation of dendritic calcite crystals in the stromatolitic tufa as incomplete biogenic skeletal crystals and their characteristic growth pattern indicates that the tufa represents a clear example of hot spring calcitic microbialite.

  16. The Arithmetical Machine Zero + 1 in Mathematics Laboratory: Instrumental Genesis and Semiotic Mediation

    Science.gov (United States)

    Maschietto, Michela

    2015-01-01

    This paper presents the analysis of two teaching experiments carried out in the context of the mathematics laboratory in a primary school (grades 3 and 4) with the use of the pascaline Zero + 1, an arithmetical machine. The teaching experiments are analysed by coordinating two theoretical frameworks, i.e. the instrumental approach and the Theory…

  17. Crop Monitoring as a Tool for Modelling the Genesis of Millet Prices in Senegal

    Science.gov (United States)

    Jacques, D.; Marinho, E.; Defourny, P.; Waldner, F.; d'Andrimont, R.

    2015-12-01

    Food security in Sahelian countries strongly relies on the ability of markets to transfer staplesfrom surplus to deficit areas. Market failures, leading to the inefficient geographical allocation of food,are expected to emerge from high transportation costs and information asymmetries that are commonin moderately developed countries. As a result, important price differentials are observed betweenproducing and consuming areas which damages both poor producers and food insecure consumers. Itis then vital for policy makers to understand how the prices of agricultural commodities are formed byaccounting for the existing market imperfections in addition to local demand and supply considerations. To address this issue, we have gathered an unique and diversified set of data for Senegal andintegrated it in a spatially explicit model that simulates the functioning of agricultural markets, that isfully consistent with the economic theory. Our departure point is a local demand and supply modelaround each market having its catchment areas determined by the road network. We estimate the localsupply of agricultural commodities from satellite imagery while the demand is assumed to be a functionof the population living in the area. From this point on, profitable transactions between areas with lowprices to areas with high prices are simulated for different levels of per kilometer transportation costand information flows (derived from call details records i.e. mobile phone data). The simulated prices are then comparedwith the actual millet prices. Despite the parsimony of the model that estimates only two parameters, i.e. the per kilometertransportation cost and the information asymmetry resulting from low levels of mobile phone activitybetween markets, it impressively explains more than 80% of the price differentials observed in the 40markets included in the analysis. In one hand these results can be used in the assessment of the socialwelfare impacts of the further development of both road and mobile phone networks in the country. Onthe other hand, the model could be further developed as a precious tool for the prediction of futurestaple prices in the country.

  18. Discussion on the genesis of uranium-producing pegmatite in Shangdan area

    Energy Technology Data Exchange (ETDEWEB)

    Mingyue, Feng [Beijing Research Inst. of Uranium Geology (China)

    1996-01-01

    This paper describes the characteristics of uranium-producing pematite, gneissic granodiorite metamorphic rocks of the Qinling Group in such aspects as petrochemical compositions, contents of trace elements (Rb and Sr etc.), initial ratio of strontium isotopes and assemblage types of accessory minerals. Through the comparison between U-barren pegmatite within the massif and U-producing pegmatite outside the massif, and the study on Sm and Nd isotope tracers, a viewpoint is presented that the U-producing pegmatite veins resulted from slow crystallization of granitic magma under relatively confined condition produced from the selective melting of the Qinling Group metamorphic rocks rather than residual magmatic crystallization from the late-stage magmatic differentiation of gneissic granodiorite (T{sub DM} is about 10 Ma).

  19. Geochemistry and genesis of the Pegmatite Limoeiro (Virgem da Lapa-MG-Brazil)

    International Nuclear Information System (INIS)

    Neves, J.M.C.; Soares, A.C.P.; Valle, R.R.

    1980-01-01

    The structure, mineralogy, geochemistry, and geological setting of the Pegmatite Limoeiro (Virgem da Lapa - MG) are presented. The country rock of this pegmatite is the Precambrian Macaubas quartz - biotite schist. The pegmatites of this region seem to be genetically related to the Coronel Murta granitoids which in the Streckeisen's diagram are scattered between granite and granodiorite. The structure of the Pegmatite Limoeiro is well displayed throught the quarring work and the following zones have been mapped: border zone, wall zone, intermediate zone, quartz core and the replacement bodies. A sample of twenty K,Na-feldspars specimens, collected according to the structure of the pegmatite, have been analysed for major elements and for Rb, Sr and Zr, using X-ray fluorescence spectrometry. Sequences of perthites from different zones, sampled all over the pegmatite, showed enrichment of Rb from the wall zone inward. This pattern supports the assumption that the studied pegmatite from Limoeiro crystallized in a restricted system from the contacts inward. The regional variation pattern of the ratios K/Rb and Rb/Ba seems to have metallogenetic implications as in other world pegmatite provinces. (Athor) [pt

  20. Diagnostic Genesis Features of Au-Ag Selenide-Telluride Mineralization of Western Java Deposits

    Directory of Open Access Journals (Sweden)

    Euis Tintin Yuningsih

    2016-01-01

    Full Text Available DOI: 10.17014/ijog.3.1.67-76The ore mineralogy of the westernmost part of West Java such as Pongkor, Cibaliung, Cikidang, Cikotok, and Cirotan are characterized by the dominance of silver-arsenic-antimony sulfosalt with silver selenides and rarely tellurides over the argentite, whereas the eastern part of West Java including Arinem and Cineam deposits are dominated by silver-gold tellurides. Mineralogy of Se-type deposits at Pongkor, Cikidang, Cibaliung, Cisungsang, and Cirotan and Te-type deposits at Arinem and Cineam shows their different geochemical characteristics. Mineralogical and geochemical differences can be explained by variation of physico-chemical conditions that existed during gold-silver deposition by applying the phase relation among sulfide, telluride, and selenide mineral association in the deposits. The relative values of ƒSe2(g, ƒTe(g, and ƒS2(g control the actual presence of selenide or telluride minerals within the West Java deposits, which also depend on their concentrations in the hydrothermal fluid. Even though the concentration of selenium in the hydrothermal fluid of Te-type deposits might have been similar or even higher than that in the Se-type, early substitution of selenium in the sulfide minerals prevents its concentration in the hydrothermal fluid to the levels for precipitating selenide minerals. Therefore, early sulfide mineral deposition from reduction fluids will not increase the ƒSe2(g/ƒS2(g ratio to form selenide minerals in Te-type deposits of Arinem and Cineam, other than selenium-bearing sulfide mineral such as Se-bearing galena or Se-bearing pyrargyrite-proustite.