WorldWideScience

Sample records for genesis

  1. Generalized Galileons: instabilities of bouncing and Genesis cosmologies and modified Genesis

    Energy Technology Data Exchange (ETDEWEB)

    Libanov, M. [Institute for Nuclear Research of the Russian Academy of Sciences,60th October Anniversary Prospect 7a, 117312 Moscow (Russian Federation); Moscow Institute of Physics and Technology,Institutskii per. 9, 141700 Dolgoprudny, Moscow Region (Russian Federation); Mironov, S. [Institute for Nuclear Research of the Russian Academy of Sciences,60th October Anniversary Prospect 7a, 117312 Moscow (Russian Federation); Rubakov, V. [Institute for Nuclear Research of the Russian Academy of Sciences,60th October Anniversary Prospect 7a, 117312 Moscow (Russian Federation); Department of Particle Physics and Cosmology, Physics Faculty,M.V. Lomonosov Moscow State University,Vorobjevy Gory, 119991, Moscow (Russian Federation)

    2016-08-18

    We study spatially flat bouncing cosmologies and models with the early-time Genesis epoch in a popular class of generalized Galileon theories. We ask whether there exist solutions of these types which are free of gradient and ghost instabilities. We find that irrespectively of the forms of the Lagrangian functions, the bouncing models either are plagued with these instabilities or have singularities. The same result holds for the original Genesis model and its variants in which the scale factor tends to a constant as t→−∞. The result remains valid in theories with additional matter that obeys the Null Energy Condition and interacts with the Galileon only gravitationally. We propose a modified Genesis model which evades our no-go argument and give an explicit example of healthy cosmology that connects the modified Genesis epoch with kination (the epoch still driven by the Galileon field, which is a conventional massless scalar field at that stage).

  2. 76 FR 54454 - Issuance of Loan Guarantee to Genesis Solar, LLC, for the Genesis Solar Energy Project

    Science.gov (United States)

    2011-09-01

    ... DEPARTMENT OF ENERGY Issuance of Loan Guarantee to Genesis Solar, LLC, for the Genesis Solar... Energy Project (GSEP), a 250-megawatt (MW) nominal capacity solar power generating facility on.../Final Environmental Impact Statement for the Genesis Solar Energy Project, Riverside County, California...

  3. Origins, transformations and key foci in instrumental genesis

    DEFF Research Database (Denmark)

    Tamborg, Andreas Lindenskov

    This paper investigates the origins of the instrumental genesis and instrumental orchestrations frameworks. This is done by reviewing instrumented activity situations, instrumental genesis, and instrumental orchestrations with the purpose of identifying their epistemological assumptions, what the...... and instrumental orchestrations have potential shortcomings since the technologies that currently exist in school contexts are rather different from the technologies instrumental genesis was originally developed to study.......This paper investigates the origins of the instrumental genesis and instrumental orchestrations frameworks. This is done by reviewing instrumented activity situations, instrumental genesis, and instrumental orchestrations with the purpose of identifying their epistemological assumptions, what...

  4. G3 : GENESIS software envrionment update

    OpenAIRE

    Castagné, Nicolas; Cadoz, Claude; Allaoui, Ali; Tache, Olivier Michel

    2009-01-01

    GENESIS3 is the new version of the GENESIS software environment for musical creation by means of mass-interaction physics network modeling. It was designed, and developed from scratch, in hindsight of more than 10 years working on and using the previous version. We take the opportunity of this birth to provide in this article (1) an analysis of the peculiarities in GENESIS, aiming at highlighting its core ?software paradigm?; and (2) an update on the features of the new version as compared to...

  5. New Results from the Flare Genesis Experiment

    Science.gov (United States)

    Rust, D. M.; Bernasconi, P. N.; Eaton, H. A.; Keller, C.; Murphy, G. A.; Schmieder, B.

    2000-05-01

    From January 10 to 27, 2000, the Flare Genesis solar telescope observed the Sun while suspended from a balloon in the stratosphere above Antarctica. The goal of the mission was to acquire long time series of high-resolution images and vector magnetograms of the solar photosphere and chromosphere. Images were obtained in the magnetically sensitive Ca I line at 6122 Angstroms and at H-alpha (6563 Angstroms). The FGE data were obtained in the context of Max Millennium Observing Campaign #004, the objective of which was to study the ``Genesis of Solar Flares and Active Filaments/Sigmoids." Flare Genesis obtained about 26,000 usable images on the 8 targeted active regions. A preliminary examination reveals a good sequence on an emerging flux region and data on the M1 flare on January 22, as well as a number of sequences on active filaments. We will present the results of our first analysis efforts. Flare Genesis was supported by NASA grants NAG5-4955, NAG5-5139, and NAG5-8331 and by NSF grant OPP-9615073. The Air Force Office of Scientific Research and the Ballistic Missile Defense Organization supported early development of the Flare Genesis Experiment.

  6. Cosmological bounce and Genesis beyond Horndeski

    Energy Technology Data Exchange (ETDEWEB)

    Kolevatov, R.; Mironov, S.; Volkova, V. [Institute for Nuclear Research of the Russian Academy of Sciences, 60th October Anniversary Prospect, 7a, 117312 Moscow (Russian Federation); Sukhov, N., E-mail: kolevatov@ms2.inr.ac.ru, E-mail: sa.mironov_1@physics.msu.ru, E-mail: nd.sukhov@physics.msu.ru, E-mail: volkova.viktoriya@physics.msu.ru [Department of Particle Physics and Cosmology, Physics Faculty, M.V. Lomonosov Moscow State University, Vorobjevy Gory, 119991 Moscow (Russian Federation)

    2017-08-01

    We study 'classical' bouncing and Genesis models in beyond Horndeski theory. We give an example of spatially flat bouncing solution that is non-singular and stable throughout the whole evolution. We also provide an example of stable geodesically complete Genesis with similar features. The model is arranged in such a way that the scalar field driving the cosmological evolution initially behaves like full-fledged beyond Horndeski, whereas at late times it becomes a massless scalar field minimally coupled to gravity.

  7. Genesis and Development of Consolidated Financial Statements

    OpenAIRE

    Kostyantyn Bezverkhiy

    2015-01-01

    In the context of economy globalization it is the mission of consolidated financial statements to meet demands of users for financial information about activities of a company group as one company. The article is devoted to study of genesis and development of consolidated financial statements of companies. Historical prerequisites of genesis of consolidated financial statements are shown as well as factors which conduced to their spreading. The approaches are elucidated to preparation of cons...

  8. Genesis machines

    CERN Document Server

    Amos, Martyn

    2014-01-01

    Silicon chips are out. Today's scientists are using real, wet, squishy, living biology to build the next generation of computers. Cells, gels and DNA strands are the 'wetware' of the twenty-first century. Much smaller and more intelligent, these organic computers open up revolutionary possibilities. Tracing the history of computing and revealing a brave new world to come, Genesis Machines describes how this new technology will change the way we think not just about computers - but about life itself.

  9. Discussion on the genesis of Zhongchuan uranium deposit

    International Nuclear Information System (INIS)

    Zhang Yulong; Zhang Chengzhong

    2008-01-01

    Through elaborating the geological setting, deposit and orebody geological charactors and hydrological features, the ore controlling factors are analysed and the genesis of Zhongchuan uranium deposit is discussed in the way of deposit occurrence, mineral asembleage and matalization ages. It is believed that uranium deposit was formed under the regional uplifting background with the exogenous mechanism and its genesis belongs to surface leaching. (authors)

  10. Genesis / Juta Kivimäe

    Index Scriptorium Estoniae

    Kivimäe, Juta, 1952-

    2003-01-01

    Poola skulptori Magdalena Schmidt-G̤ra installatsioonid "Genesis I, II" rahvusraamatukogu fuajees ja peanäitusesaalis, kus oli samal ajal eksponeeritud eesti nahakunstnike Luule Maari ja Ruuda Maarandi köitenäitus

  11. On the genesis of the uraniferous deposits I; Consideraciones sobre la genesis de los yacimientos uraniferos. I.

    Energy Technology Data Exchange (ETDEWEB)

    Mingarro, E

    1964-07-01

    The main problems of the genesis of uranium deposits as hydro thermals are objectively considered here under three aspects: uranium source transport and deposition. The transport of uranium can be effected under a tetravalent form, or as complex ions of hexavalent uranium: as uranyl ion (UO{sub 2}){sup 2}+ or under complex carbonic or sulfuric forms, such as UO{sub 2}(XO{sub n}){sub 2}{sup 2}- or UO{sub 2}(XO{sub n}){sub 3}{sup 4}-. These three ways of transport correspond to the three basic geochemical para genesis of uranium: uranium-titanium, uranium-cobalt, uranium. Deposition is currently made by reduction and in some way is no dependent of mineralogical association. (Author) 61 refs.

  12. Genesis and Evolution of Interfaces in Product Architecture

    DEFF Research Database (Denmark)

    Donmez, Mehmet; Hsuan, Juliana

    Interfaces are elements of the product architecture that facilitates innovation and enables an organization to leverage the trade-off between cost and performance of its products. Despite the importance of interfaces for organizations, little is known about their genesis and evolution. In this st......Interfaces are elements of the product architecture that facilitates innovation and enables an organization to leverage the trade-off between cost and performance of its products. Despite the importance of interfaces for organizations, little is known about their genesis and evolution...

  13. A Region-Based GeneSIS Segmentation Algorithm for the Classification of Remotely Sensed Images

    Directory of Open Access Journals (Sweden)

    Stelios K. Mylonas

    2015-03-01

    Full Text Available This paper proposes an object-based segmentation/classification scheme for remotely sensed images, based on a novel variant of the recently proposed Genetic Sequential Image Segmentation (GeneSIS algorithm. GeneSIS segments the image in an iterative manner, whereby at each iteration a single object is extracted via a genetic-based object extraction algorithm. Contrary to the previous pixel-based GeneSIS where the candidate objects to be extracted were evaluated through the fuzzy content of their included pixels, in the newly developed region-based GeneSIS algorithm, a watershed-driven fine segmentation map is initially obtained from the original image, which serves as the basis for the forthcoming GeneSIS segmentation. Furthermore, in order to enhance the spatial search capabilities, we introduce a more descriptive encoding scheme in the object extraction algorithm, where the structural search modules are represented by polygonal shapes. Our objectives in the new framework are posed as follows: enhance the flexibility of the algorithm in extracting more flexible object shapes, assure high level classification accuracies, and reduce the execution time of the segmentation, while at the same time preserving all the inherent attributes of the GeneSIS approach. Finally, exploiting the inherent attribute of GeneSIS to produce multiple segmentations, we also propose two segmentation fusion schemes that operate on the ensemble of segmentations generated by GeneSIS. Our approaches are tested on an urban and two agricultural images. The results show that region-based GeneSIS has considerably lower computational demands compared to the pixel-based one. Furthermore, the suggested methods achieve higher classification accuracies and good segmentation maps compared to a series of existing algorithms.

  14. Lean Management Genesis

    Directory of Open Access Journals (Sweden)

    Parkes Aneta

    2015-12-01

    Full Text Available Lean Management is a philosophy and management concept, based on reduction of the waste and resources used in the process of producing goods and providing services. Lean Management genesis dates back to scientific management in America (for example concepts of H. Ford and F.W. Taylor and quality management, including development of TQM concept. Japanese Toyota Production System has been inspired by chosen elements of these concepts, and then it evolved towards global concept called Toyota Way (which connects production rules with values and work attitude.

  15. Lectures on Genesis 1:26-2:3 and 2:21-25

    DEFF Research Database (Denmark)

    Stjerna, Kirsi; Pedersen, Else Marie Wiberg

    2017-01-01

    This introduction to parts of Luther's lectures on Genesis (1535-45), namely his lectures on Genesis 1:26-2:3 and 2:21-25, discusses the reformer's grappling with the text in its historical and theological context. Not least is the question of gender taken under scrutiny, as the two authors, Kirsi...

  16. On the genesis of the uraniferous deposits I

    International Nuclear Information System (INIS)

    Mingarro, E.

    1964-01-01

    The main problems of the genesis of uranium deposits as hydro thermals are objectively considered here under three aspects: uranium source transport and deposition. The transport of uranium can be effected under a tetravalent form, or as complex ions of hexavalent uranium: as uranyl ion (UO 2 ) 2 + or under complex carbonic or sulfuric forms, such as UO 2 (XO n ) 2 2 - or UO 2 (XO n ) 3 4 -. These three ways of transport correspond to the three basic geochemical para genesis of uranium: uranium-titanium, uranium-cobalt, uranium. Deposition is currently made by reduction and in some way is no dependent of mineralogical association. (Author) 61 refs

  17. Python as a federation tool for GENESIS 3.0.

    Directory of Open Access Journals (Sweden)

    Hugo Cornelis

    Full Text Available The GENESIS simulation platform was one of the first broad-scale modeling systems in computational biology to encourage modelers to develop and share model features and components. Supported by a large developer community, it participated in innovative simulator technologies such as benchmarking, parallelization, and declarative model specification and was the first neural simulator to define bindings for the Python scripting language. An important feature of the latest version of GENESIS is that it decomposes into self-contained software components complying with the Computational Biology Initiative federated software architecture. This architecture allows separate scripting bindings to be defined for different necessary components of the simulator, e.g., the mathematical solvers and graphical user interface. Python is a scripting language that provides rich sets of freely available open source libraries. With clean dynamic object-oriented designs, they produce highly readable code and are widely employed in specialized areas of software component integration. We employ a simplified wrapper and interface generator to examine an application programming interface and make it available to a given scripting language. This allows independent software components to be 'glued' together and connected to external libraries and applications from user-defined Python or Perl scripts. We illustrate our approach with three examples of Python scripting. (1 Generate and run a simple single-compartment model neuron connected to a stand-alone mathematical solver. (2 Interface a mathematical solver with GENESIS 3.0 to explore a neuron morphology from either an interactive command-line or graphical user interface. (3 Apply scripting bindings to connect the GENESIS 3.0 simulator to external graphical libraries and an open source three dimensional content creation suite that supports visualization of models based on electron microscopy and their conversion to

  18. Python as a federation tool for GENESIS 3.0.

    Science.gov (United States)

    Cornelis, Hugo; Rodriguez, Armando L; Coop, Allan D; Bower, James M

    2012-01-01

    The GENESIS simulation platform was one of the first broad-scale modeling systems in computational biology to encourage modelers to develop and share model features and components. Supported by a large developer community, it participated in innovative simulator technologies such as benchmarking, parallelization, and declarative model specification and was the first neural simulator to define bindings for the Python scripting language. An important feature of the latest version of GENESIS is that it decomposes into self-contained software components complying with the Computational Biology Initiative federated software architecture. This architecture allows separate scripting bindings to be defined for different necessary components of the simulator, e.g., the mathematical solvers and graphical user interface. Python is a scripting language that provides rich sets of freely available open source libraries. With clean dynamic object-oriented designs, they produce highly readable code and are widely employed in specialized areas of software component integration. We employ a simplified wrapper and interface generator to examine an application programming interface and make it available to a given scripting language. This allows independent software components to be 'glued' together and connected to external libraries and applications from user-defined Python or Perl scripts. We illustrate our approach with three examples of Python scripting. (1) Generate and run a simple single-compartment model neuron connected to a stand-alone mathematical solver. (2) Interface a mathematical solver with GENESIS 3.0 to explore a neuron morphology from either an interactive command-line or graphical user interface. (3) Apply scripting bindings to connect the GENESIS 3.0 simulator to external graphical libraries and an open source three dimensional content creation suite that supports visualization of models based on electron microscopy and their conversion to computational models

  19. Finding the Genesis for a Thesis

    Science.gov (United States)

    Caroll, Joyce Armstrong

    2013-01-01

    This article describes a prewriting heuristics strategy that can help students find the genesis of their thesis. The 3 functions of the heuristic procedure are that it aids in retrieving relevant information stored in the mind; draws attention to important information that can be further researched or accessed; and prepares the mind for the…

  20. Photovoltaic technologies and the genesis project

    International Nuclear Information System (INIS)

    Kuwano, Y.

    1994-01-01

    In this paper, the author first presents briefly global environmental problems and energy problems, as well as recent trends in representative types of solar cell. Next, he gives examples of applications for these solar cells, and finally discusses future prospects for solar cells in the form of the GENESIS project. (TEC). 12 figs., 4 refs

  1. Decrease of tropical cyclone genesis frequency in the western North Pacific since 1960s

    Science.gov (United States)

    Hu, Feng; Li, Tim; Liu, Jia; Bi, Mingyu; Peng, Melinda

    2018-03-01

    Tropical cyclone (TC) genesis frequency in the western North Pacific (WNP) during 1960-2014 shows a step-by-step decrease on interdecadal timescale, in accordance to the phase of the Interdecadal Pacific Oscillation (IPO). The environmental parameters responsible for the interdecadal change of TC genesis frequency were investigated. It was found that vertical wind shear especially the zonal wind shear plays a critical role, while other parameters such as sea surface temperature (SST), vertical velocity, divergence, humidity and maximum potential intensity cannot explain the step-by-step decrease of TC genesis frequency. A further diagnosis shows that the interdecadal change of vertical wind shear is caused by SST and associated rainfall pattern changes across the Indo-Pacific Ocean. A stronger warming in the Indian Ocean/western Pacific from 1960-1976 to 1977-1998 led to enhanced convection over the Maritime Continent and thus strengthened vertical shear over the key TC genesis region in the WNP. A La Nina-like SST pattern change from 1977-1998 to 1999-2014 led to a strengthened Walker circulation in the tropical Pacific, which further enhanced the vertical shear and decreased TC genesis frequency in the WNP.

  2. Augustine on redemption in Genesis 1�3

    Directory of Open Access Journals (Sweden)

    Edward L. Smither

    2014-01-01

    Full Text Available Many theologians, including those concerned with theology of mission, frame the dramaof God�s story and mission (missio Dei through the three major acts of creation, fall andredemption. Others add that the new creation ought to be regarded as a fourth act. Althoughthis framework describes the entire biblical narrative, creation, fall and the hope of redemptionare, of course, quite present in the first three chapters of Genesis. In this article, I endeavouredto engage with the commentaries of the African church father Augustine of Hippo (354�430 CE to grasp his thoughts on redemption in Genesis 1�3. In his Genesis works, Augustinewas primarily concerned with clarifying the doctrine of creation and, relatively speaking, hadfar less to say about redemption. That said, Augustine was, quite interested with Scripture�sstory of redemption in his magnum opus De Civitate Dei [City of God]. Thus, in this article, Iexplored two major questions: firstly, why did Augustine pay so little attention to redemptionin Genesis 1�3? Secondly, how did he articulate and relate redemption in these chapters? Itwas shown that whilst his primary focus was to articulate creation, his thoughts on redemptionwere probably limited some because of the insufficiency of his Old Latin Bible translation andperhaps because of other distractions in ministry. Furthermore, it was argued that Augustine�sdoctrine of redemption was a subset of his discussion on creation � specifically, that the secondAdam (Christ brought new life to God�s image bearers affected by the fall of the first Adam.Intradisciplinary and/or interdisciplinary implications: My aim was to establish Augustine�sthoughts on redemption as a point of dialogue for theologians of mission endeavouring toclarify a theology of mission. As most mission theologians do not consult Augustine in theirwork and as most early Christian scholars do not read Augustine missionally, this studyoffered fresh insights for

  3. Safety analysis of a pool Genesis II irradiator

    International Nuclear Information System (INIS)

    Rodrigues Junior, Ary de A.

    2011-01-01

    The Genesis II Irradiator manufactured by GRAT * STAR Inc. (USA) is a category III gamma irradiator in which the sealed source is contained in a water filled storage pool and is shielded permanently, i.e. the material has to move down to the source. Even though the pool is 5.6 m deep, what would happen if the water level lowered? There are a series of safety devices that will avoid this situation and calculations show that the water level has to be very low in order to deliver a significant dose; moreover, only in case a person remains at the border of the pool for a long time this would be risky. In conclusion, it is practically impossible for someone to be exposed to radiation from a Genesis II Irradiator source. (author)

  4. Slip rate and tremor genesis in Cascadia

    Science.gov (United States)

    Wech, Aaron G.; Bartlow, Noel M.

    2014-01-01

    At many plate boundaries, conditions in the transition zone between seismogenic and stable slip produce slow earthquakes. In the Cascadia subduction zone, these events are consistently observed as slow, aseismic slip on the plate interface accompanied by persistent tectonic tremor. However, not all slow slip at other plate boundaries coincides spatially and temporally with tremor, leaving the physics of tremor genesis poorly understood. Here we analyze seismic, geodetic, and strainmeter data in Cascadia to observe for the first time a large, tremor-generating slow earthquake change from tremor-genic to silent and back again. The tremor falls silent at reduced slip speeds when the migrating slip front pauses as it loads the stronger adjacent fault segment to failure. The finding suggests that rheology and slip-speed-regulated stressing rate control tremor genesis, and the same section of fault can slip both with and without detectable tremor, limiting tremor's use as a proxy for slip.

  5. Is the poleward migration of tropical cyclone maximum intensity associated with a poleward migration of tropical cyclone genesis?

    Science.gov (United States)

    Daloz, Anne Sophie; Camargo, Suzana J.

    2018-01-01

    A recent study showed that the global average latitude where tropical cyclones achieve their lifetime-maximum intensity has been migrating poleward at a rate of about one-half degree of latitude per decade over the last 30 years in each hemisphere. However, it does not answer a critical question: is the poleward migration of tropical cyclone lifetime-maximum intensity associated with a poleward migration of tropical cyclone genesis? In this study we will examine this question. First we analyze changes in the environmental variables associated with tropical cyclone genesis, namely entropy deficit, potential intensity, vertical wind shear, vorticity, skin temperature and specific humidity at 500 hPa in reanalysis datasets between 1980 and 2013. Then, a selection of these variables is combined into two tropical cyclone genesis indices that empirically relate tropical cyclone genesis to large-scale variables. We find a shift toward greater (smaller) average potential number of genesis at higher (lower) latitudes over most regions of the Pacific Ocean, which is consistent with a migration of tropical cyclone genesis towards higher latitudes. We then examine the global best track archive and find coherent and significant poleward shifts in mean genesis position over the Pacific Ocean basins.

  6. Genesis nature of financial strategy

    OpenAIRE

    O.V. Pashchenko

    2015-01-01

    The article is devoted to the study of the origin and history of the interpretation of the genesis of «strategy», «financial strategy», its elements and composite types. Scientists studied different views on the concept of strategy. Several specific positions founders of different approaches to define the strategy of schools operating strategies involved in the formulation and implementation of the concept of «strategy». Evaluation of different schools of strategies that deepened understandin...

  7. ABRAHAM IN GALATIANS AND IN GENESIS1

    African Journals Online (AJOL)

    In Genesis 12-25, attention is paid to the promise of land and on Abraham as a blessing to ... It is a truism to claim that Abraham serves as an important figure in both the ..... them rest (Jos 21:43), became the ground for hope for the people who.

  8. GENESI-DR: Discovery, Access and on-Demand Processing in Federated Repositories

    Science.gov (United States)

    Cossu, Roberto; Pacini, Fabrizio; Parrini, Andrea; Santi, Eliana Li; Fusco, Luigi

    2010-05-01

    GENESI-DR (Ground European Network for Earth Science Interoperations - Digital Repositories) is a European Commission (EC)-funded project, kicked-off early 2008 lead by ESA; partners include Space Agencies (DLR, ASI, CNES), both space and no-space data providers such as ENEA (I), Infoterra (UK), K-SAT (N), NILU (N), JRC (EU) and industry as Elsag Datamat (I), CS (F) and TERRADUE (I). GENESI-DR intends to meet the challenge of facilitating "time to science" from different Earth Science disciplines in discovery, access and use (combining, integrating, processing, …) of historical and recent Earth-related data from space, airborne and in-situ sensors, which are archived in large distributed repositories. In fact, a common dedicated infrastructure such as the GENESI-DR one permits the Earth Science communities to derive objective information and to share knowledge in all environmental sensitive domains over a continuum of time and a variety of geographical scales so addressing urgent challenges such as Global Change. GENESI-DR federates data, information and knowledge for the management of our fragile planet in line with one of the major goals of the many international environmental programmes such as GMES, GEO/GEOSS. As of today, 12 different Digital Repositories hosting more than 60 heterogeneous dataset series are federated in GENESI-DR. Series include satellite data, in situ data, images acquired by airborne sensors, digital elevation models and model outputs. ESA has started providing access to: Category-1 data systematically available on Internet; level 3 data (e.g., GlobCover map, MERIS Global Vegetation Index); ASAR products available in ESA Virtual Archive and related to the Supersites initiatives. In all cases, existing data policies and security constraints are fully respected. GENESI-DR also gives access to Grid and Cloud computing resources allowing authorized users to run a number of different processing services on the available data. The GENESI

  9. Tropical cyclone genesis in the Southern Hemisphere and its relationship with the ENSO

    Energy Technology Data Exchange (ETDEWEB)

    Kuleshov, Y.; Qi, L. [Australian Bureau of Meteorology, Melbourne, VIC (Australia). National Climate Centre; Chane Ming, F.; Chouaibou, I.; Hoareau, C. [UMR CNRS-Meteo-France-Univ. de la Reunion, La Reunion (France). Lab. de l' Atmosphere et des Cyclones; Roux, F. [Paul Sabatier Univ., CNRS, Toulouse (France). Lab. d' Aerologie

    2009-07-01

    Tropical cyclogenesis climatology over the South Indian and South Pacific Oceans has been developed using a new tropical cyclone (TC) archive for the Southern Hemisphere, and changes in geographical distribution of areas favourable for TC genesis related to changes in the El Nino-Southern Oscillation (ENSO) phases have been investigated. To explain these changes, large-scale environmental variables which influence TC genesis and development such as sea surface temperatures (SSTs), relative humidity in mid-troposphere, vertical wind shear and lower tropospheric vorticity have been examined. In the South Indian Ocean, reduction of TC genesis in the western part of the basin and its increase in the eastern part as well as displacement of the area favourable for TC genesis further away from the equator during La Nina events compared to El Nino events can be explained by changes in geographical distribution of relative humidity and vorticity across the basin as primary contributors; positive anomalies of SSTs observed during La Nina seasons in the eastern part of the basin additionally contribute to enhanced cyclogenesis near the Western Australia. In the South Pacific Ocean, changes in geographical distribution of relative humidity and vorticity appear to be the key large-scale environmental factors responsible for enhanced TC genesis in the eastern (western) part of the basin as well as for the northeast (southwest) shift of points of cyclogenesis during El Nino (La Nina) events, with vertical wind shear and SSTs as additional contributing large-scale environmental variables. (orig.)

  10. 75 FR 69458 - Notice of Availability of the Record of Decision for the Genesis Solar Energy Project and...

    Science.gov (United States)

    2010-11-12

    ..., LVRWB09B2520] Notice of Availability of the Record of Decision for the Genesis Solar Energy Project [email protected] . SUPPLEMENTARY INFORMATION: Genesis Solar, LLC, a wholly owned subsidiary of NextEra Energy Resources, filed right-of-way (ROW) application CACA-048880 for the proposed Genesis Solar Energy...

  11. Cellulose Acetate Replica Cleaning Study of Genesis Non-Flight Sample 3CZ00327

    Science.gov (United States)

    Kuhlman, K. R.; Schmeling, M.; Gonzalez, C. P.; Allton, J. H.; Burnett, D. S.

    2014-01-01

    The Genesis mission collected solar wind and brought it back to Earth in order to provide precise knowledge of solar isotopic and elemental compositions. The ions in the solar wind were stopped in the collectors at depths on the order of 10 to a few hundred nanometers. This shallow implantation layer is critical for scientific analysis of the composition of the solar wind and must be preserved throughout sample handling, cleaning, processing, distribution, preparation and analysis. We are working interactively with the community of scientists analyzing Genesis samples, using our unique laboratory facilities -- and, where needed, our unique cleaning techniques -- to significantly enhance the science return from the Genesis mission. This work is motivated by the need to understand the submicron contamination on the collectors in the Genesis payload as recovered from the crash site in the Utah desert, and -- perhaps more importantly -- how to remove it. That is, we are evaluating the effectiveness of the wet-chemical "cleaning" steps used by various investigators, to enable them to design improved methods of stripping terrestrial contamination from surfaces while still leaving the solar-wind signal intact.

  12. Tropical cyclone genesis in the Southern Hemisphere and its relationship with the ENSO

    Directory of Open Access Journals (Sweden)

    Y. Kuleshov

    2009-06-01

    Full Text Available Tropical cyclogenesis climatology over the South Indian and South Pacific Oceans has been developed using a new tropical cyclone (TC archive for the Southern Hemisphere, and changes in geographical distribution of areas favourable for TC genesis related to changes in the El Niño-Southern Oscillation (ENSO phases have been investigated. To explain these changes, large-scale environmental variables which influence TC genesis and development such as sea surface temperatures (SSTs, relative humidity in mid-troposphere, vertical wind shear and lower tropospheric vorticity have been examined. In the South Indian Ocean, reduction of TC genesis in the western part of the basin and its increase in the eastern part as well as displacement of the area favourable for TC genesis further away from the equator during La Niña events compared to El Niño events can be explained by changes in geographical distribution of relative humidity and vorticity across the basin as primary contributors; positive anomalies of SSTs observed during La Niña seasons in the eastern part of the basin additionally contribute to enhanced cyclogenesis near the Western Australia. In the South Pacific Ocean, changes in geographical distribution of relative humidity and vorticity appear to be the key large-scale environmental factors responsible for enhanced TC genesis in the eastern (western part of the basin as well as for the northeast (southwest shift of points of cyclogenesis during El Niño (La Niña events, with vertical wind shear and SSTs as additional contributing large-scale environmental variables.

  13. Genesis Eco Systems, Inc. soil washing process

    International Nuclear Information System (INIS)

    Cena, R.J.

    1994-01-01

    The Genesis soil washing system is an integrated system of modular design allowing for maximum material handling capabilities, with optimized use of space for site mobility. The Surfactant Activated Bio-enhanced Remediation Equipment-Generation 1 (SABRE-1, Patent Applied For) modification was developed specifically for removing petroleum byproducts from contaminated soils. Scientifically formulated surfactants, introduced by high pressure spray nozzles, displace the contaminant from the surface of the soil particles into the process solution. Once the contaminant is dispersed into the liquid fraction of the process, it is either mechanically removed, chemically oxidized, or biologically oxidized. The contaminated process water is pumped through the Genesis Biosep (Patent Applied For) filtration system where the fines portion is flocculated, and the contaminant-rich liquid portion is combined with an activated mixture of nutrients and carefully selected bacteria to decompose the hydrocarbon fraction. The treated soil and dewatered fines are transferred to a bermed stockpile where bioremediation continues during drying. The process water is reclaimed, filtered, and recycled within the system

  14. Towards a Statistical Model of Tropical Cyclone Genesis

    Science.gov (United States)

    Fernandez, A.; Kashinath, K.; McAuliffe, J.; Prabhat, M.; Stark, P. B.; Wehner, M. F.

    2017-12-01

    Tropical Cyclones (TCs) are important extreme weather phenomena that have a strong impact on humans. TC forecasts are largely based on global numerical models that produce TC-like features. Aspects of Tropical Cyclones such as their formation/genesis, evolution, intensification and dissipation over land are important and challenging problems in climate science. This study investigates the environmental conditions associated with Tropical Cyclone Genesis (TCG) by testing how accurately a statistical model can predict TCG in the CAM5.1 climate model. TCG events are defined using TECA software @inproceedings{Prabhat2015teca, title={TECA: Petascale Pattern Recognition for Climate Science}, author={Prabhat and Byna, Surendra and Vishwanath, Venkatram and Dart, Eli and Wehner, Michael and Collins, William D}, booktitle={Computer Analysis of Images and Patterns}, pages={426-436}, year={2015}, organization={Springer}} to extract TC trajectories from CAM5.1. L1-regularized logistic regression (L1LR) is applied to the CAM5.1 output. The predictions have nearly perfect accuracy for data not associated with TC tracks and high accuracy differentiating between high vorticity and low vorticity systems. The model's active variables largely correspond to current hypotheses about important factors for TCG, such as wind field patterns and local pressure minima, and suggests new routes for investigation. Furthermore, our model's predictions of TC activity are competitive with the output of an instantaneous version of Emanuel and Nolan's Genesis Potential Index (GPI) @inproceedings{eman04, title = "Tropical cyclone activity and the global climate system", author = "Kerry Emanuel and Nolan, {David S.}", year = "2004", pages = "240-241", booktitle = "26th Conference on Hurricanes and Tropical Meteorology"}.

  15. OUTCOMES REVIEW OF TOTAL KNEE REPLACEMENT WITH GENESIS II TOTAL KNEE SYSTEM: AUSTRALIAN ORTHOPAEDIC ASSOCIATION NATIONAL JOINT REPLACEMENT REGISTRY DATA

    Directory of Open Access Journals (Sweden)

    N. L. Logvinov

    2014-01-01

    Full Text Available ABSTRACT. The goal of the article was to review Genesis II Total Knee System use according to AoA NJRR report. Genesis II has been widely used in Russian Federation since 1996. The AoA NJRR report was studied in order to learn connection between number of revision procedures and surgeon’s skills or type of the System, adequate choice among cemented, cementless and hybrid fixation, number of surgeries using Genesis II Total Knee System annually, average revision rate for Genesis II and early cumulative revision rate.CONCLUSION. The systematic study of AoA NJRR allows us to make a conclusion that cemented fixation of Genesis II Total Knee System is mostly effective, and this fact is confirmed by domestic experience. 

  16. Kollig op Genesis 1-3: 'n verslag van verskuiwende denke en geloof

    OpenAIRE

    Spangenberg, Sakkie

    2014-01-01

    The author narrates how his views concerning Gen 1-3 have changed over the past forty years. He enrolled for theological training at the University of Stellenbosch during the seventies of the previous century and had to study the book Hoe lezen wij Genesis 2 en 3? ("How should we read Genesis 2 and 3?"). The book had been written by B. J. Oosterhoff, a Dutch scholar who argued a case for a symbolic reading of the text. Since then the author has become acquainted with the paradigm change in th...

  17. 192 RE-INTERPRETING GENESIS 34 IN THE LIGHT OF ...

    African Journals Online (AJOL)

    User

    notoriety as one of the prime security challenges confronting the country. Genesis .... thing has been done to them by Shechem. ... The use of the word חַטֶבּ which means security ..... students and internet writers; and the polylectic approach.

  18. Genesis of cluster associations of enterprises

    Directory of Open Access Journals (Sweden)

    Pulina Tetyana V.

    2013-03-01

    Full Text Available The goal of the article is the study of genesis of creation of cluster associations of enterprises. It considers genesis of cluster definitions. It shows and analyses components that define the “cluster” concept. Researchers from many countries offer a significant number of definitions of the “cluster” term specifically in the economic direction, but there is no single generally accepted definition as of today. This fact is the result of a significant diversity of cluster structures. The article conducts a comparative analysis of classifications of cluster associations of enterprises. It identifies advantages and shortcomings of the cluster approach both from the position of an enterprise and from the position of a regional economy administration. The article marks out specific features of the life cycle of cluster associations of enterprises, which consists of the preparatory stage and stage of commercialisation. Majority of studies consider the preparatory stage and the stage of commercialisation, which consists of the following stages: entering market with a common brand, growth, maturity and crisis – is, practically, not considered. Taking into account the fact that the main result of cluster activity is the synergetic effect from mutually beneficial co-operation and activity results facilitate ensuring competitiveness of cluster enterprises, regional and national economies, the author gives own definition of a cluster.

  19. The genesis and evolution of the African Field Epidemiology Network

    African Journals Online (AJOL)

    The genesis and evolution of the African Field Epidemiology Network. David Mukanga, Mufuta Tshimanga, Frederick Wurapa, David Serwada, George Pariyo, Fred Wabwire-Mangen, Sheba Gitta, Stella Chungong, Murray Trostle, Peter Nsubuga ...

  20. Folk narratives structures in Genesis 2, 4 -3, 24

    Directory of Open Access Journals (Sweden)

    Magdalena Flores Ferres

    2015-04-01

    Full Text Available The objective of this research is to demonstrate that Genesis 2.4 to 3.24, can be considered, from the perspective of the structure, a traditional folk story, since it contains the morphologic elements of this type of literature. To that end, in this paper we focus on the study of the structure of the folk tale. The structure of the action sequence of such tales is interesting from differente disciplines, due to its remarkable stability. To that end, we will review the postulates proposed by Vladimir Propp in his book “Morphology of the Folktale” (1928. From these theoretical foundations, we conducted a contrastive analysis of the Genesis 2.4 to 3.24, in paralell to the russian folktale “The Cat, the Rooster and the Fox” (Afanasiev, 1981, after which it was found that both tales have the same narrative structure.

  1. Post-Disaster Image Processing for Damage Analysis Using GENESI-DR, WPS and Grid Computing

    OpenAIRE

    Bielski, Conrad; Gentilini, Simone; Pappalardo, Marco

    2011-01-01

    The goal of the two year Ground European Network for Earth Science Interoperations-Digital Repositories (GENESI-DR) project was to build an open and seamless access service to Earth science digital repositories for European and world-wide science users. In order to showcase GENESI-DR, one of the developed technology demonstrators focused on fast search, discovery, and access to remotely sensed imagery in the context of post-disaster building damage assessment. This paper descri...

  2. Cleaning Genesis Mission Payload for Flight with Ultra-Pure Water and Assembly in ISO Class 4 Environment

    Science.gov (United States)

    Allton, Judith H.

    2012-01-01

    Genesis mission to capture and return to Earth solar wind samples had very stringent contamination control requirements in order to distinguish the solar atoms from terrestrial ones. Genesis mission goals were to measure solar composition for most of the periodic table, so great care was taken to avoid particulate contamination. Since the number 1 and 2 science goals were to determine the oxygen and nitrogen isotopic composition, organic contamination was minimized by tightly controlling offgassing. The total amount of solar material captured in two years is about 400 micrograms spread across one sq m. The contamination limit requirement for each of C, N, and O was <1015 atoms/sq cm. For carbon, this is equivalent to 10 ng/cm2. Extreme vigilance was used in pre-paring Genesis collectors and cleaning hardware for flight. Surface contamination on polished silicon wafers, measured in Genesis laboratory is approximately 10 ng/sq cm.

  3. Nursing perspective on the Genesis account of creation.

    Science.gov (United States)

    Geary, Heidi D; Cone, Pamela H

    2012-01-01

    Biblical accounts of creation tell the origin of the world and the beginning of God's relationship with humankind. Azusa Pacific University assigns graduate nursing students a faith integration project analyzing Creation accounts through the eyes of a nurse researcher. This report integrates eight students' investigations of Genesis 1 and 2, offering deep, rich insight into nursing practice.

  4. Molecular Contamination on Anodized Aluminum Components of the Genesis Science Canister

    Science.gov (United States)

    Burnett, D. S.; McNamara, K. M.; Jurewicz, A.; Woolum, D.

    2005-01-01

    Inspection of the interior of the Genesis science canister after recovery in Utah, and subsequently at JSC, revealed a darkening on the aluminum canister shield and other canister components. There has been no such observation of film contamination on the collector surfaces, and preliminary spectroscopic ellipsometry measurements support the theory that the films observed on the anodized aluminum components do not appear on the collectors to any significant extent. The Genesis Science Team has made an effort to characterize the thickness and composition of the brown stain and to determine if it is associated with molecular outgassing.Detailed examination of the surfaces within the Genesis science canister reveals that the brown contamination is observed to varying degrees, but only on surfaces exposed in space to the Sun and solar wind hydrogen. In addition, the materials affected are primarily composed of anodized aluminum. A sharp line separating the sun and shaded portion of the thermal closeout panel is shown. This piece was removed from a location near the gold foil collector within the canister. Future plans include a reassembly of the canister components to look for large-scale patterns of contamination within the canister to aid in revealing the root cause.

  5. Delimitation Markers, Chapter Division, Syntax and Literary Structure: the Case of Genesis 37:1–2

    NARCIS (Netherlands)

    van Peursen, W.T.; Korpel, Marjo; Sanders, Paul

    2017-01-01

    Many modern Bible translations insert a heading between the end of Genesis 36 and the beginning of Genesis 37 such as ‘Joseph and his brothers’ or ‘Joseph’s dreams’. This suggests (1) that a new section starts at 37:1 and (2) that this section contains the Joseph story. That 37:1 marks a new start

  6. Genesis Science Team Report on Mission Status

    Science.gov (United States)

    Burnett, D. S.

    2005-12-01

    The Genesis Discovery Mission exposed pure materials to the solar wind at the L1 Lagrangian point for 27 months between December 2001 and April 2004. These were returned for analysis in terrestrial laboratories in Sept 2004. The general science objectives for Genesis are: (1) measure solar isotopic abundance ratios to the precision required for planetary science problems, (2) improve the accuracy of photospheric elemental abundances by a least a factor of three, (3) provide independent analyses of the 3 major solar wind regimes and (4) provide a reservoir of solar matter for subsequent studies. Based on these general objectives, we are working towards a list of 18 specific prioritized measurement objectives, the first 5 of which are isotopic measurements. The two highest priority objectives are the isotopic compositions of O and N; to obtain a higher signal to background ratio for these elements, a concentrator (focusing ion telescope) was built at LANL to provide a factor of 20 fluence enhancement for elements lighter than P on a 30 mm radius target. The concentrator performed well in flight. A variety of other collector materials, tailored to specific analytical approaches, were mounted in 5 arrays of 55 hexagons, 4 cm point to point. Three of the arrays were used to provide the independent regime (coronal hole, low speed interstream, and coronal mass ejection) samples. The solar wind regime was measured by LANL Solar Wind Monitors on the Genesis spacecraft and the appropriate array exposed while the inappropriate array remained shielded. Array switchouts were carried out flawlessly during flight. Sample analyses have been slowed considerably by a parachute deployment failure which caused a crash of the sample return capsule upon reentry and by the presence of an in-flight contamination film, affectionately referred to as the brown stain. The crash has led to major loss of collector materials, along with significant pitting and scratching of the surviving

  7. Tropical Cyclone Genesis Efficiency: Mid-Level Versus Bottom Vortex

    Science.gov (United States)

    2011-12-16

    storm strength). Figure 4b shows the time evolutions of the corresponding maximum surface wind speed from the four experiments. Based on the definition...Pacific during summer. Mon. Wea. Rev., 124, 2245–2266. Chen, S. S. and W. M. Frank, 1993: A numerical study of the genesis of extratropical convective

  8. GENESI-DR Portal: a scientific gateway to distributed repositories

    Science.gov (United States)

    Goncalves, Pedro; Brito, Fabrice; D'Andria, Fabio; Cossu, Roberto; Fusco, Luigi

    2010-05-01

    GENESI-DR (Ground European Network for Earth Science Interoperations - Digital Repositories) is a European Commission (EC)-funded project, kicked-off early 2008 lead by ESA; partners include Space Agencies (DLR, ASI, CNES), both space and no-space data providers such as ENEA (I), Infoterra (UK), K-SAT (N), NILU (N), JRC (EU) and industry as Elsag Datamat (I), CS (F) and TERRADUE (I). GENESI-DR intends to meet the challenge of facilitating "time to science" from different Earth Science disciplines in discovery, access and use (combining, integrating, processing, …) of historical and recent Earth-related data from space, airborne and in-situ sensors, which are archived in large distributed repositories. "Discovering" which data are available on a "geospatial web" is one of the main challenges ES scientists have to face today. Some well- known data sets are referred to in many places, available from many sources. For core information with a common purpose many copies are distributed, e.g., VMap0, Landsat, and SRTM. Other data sets in low or local demand may only be found in a few places and niche communities. Relevant services, results of analysis, applications and tools are accessible in a very scattered and uncoordinated way, often through individual initiatives from Earth Observation mission operators, scientific institutes dealing with ground measurements, service companies or data catalogues. In the discourse of Spatial Data Infrastructures, there are "catalogue services" - directories containing information on where spatial data and services can be found. For metadata "records" describing spatial data and services, there are "registries". The Geospatial industry coins specifications for search interfaces, where it might do better to reach out to other information retrieval and Internet communities. These considerations are the basis for the GENESI-DR scientific portal, which adopts a simple model allowing the geo-spatial classification and discovery of

  9. ENSO Effect on East Asian Tropical Cyclone Landfall via Changes in Tracks and Genesis in a Statistical Model

    Science.gov (United States)

    Yonekura, Emmi; Hall, Timothy M.

    2014-01-01

    Improvements on a statistical tropical cyclone (TC) track model in the western North Pacific Ocean are described. The goal of the model is to study the effect of El Nino-Southern Oscillation (ENSO) on East Asian TC landfall. The model is based on the International Best-Track Archive for Climate Stewardship (IBTrACS) database of TC observations for 1945-2007 and employs local regression of TC formation rates and track increments on the Nino-3.4 index and seasonally varying climate parameters. The main improvements are the inclusion of ENSO dependence in the track propagation and accounting for seasonality in both genesis and tracks. A comparison of simulations of the 1945-2007 period with observations concludes that the model updates improve the skill of this model in simulating TCs. Changes in TC genesis and tracks are analyzed separately and cumulatively in simulations of stationary extreme ENSO states. ENSO effects on regional (100-km scale) landfall are attributed to changes in genesis and tracks. The effect of ENSO on genesis is predominantly a shift in genesis location from the southeast in El Nino years to the northwest in La Nina years, resulting in higher landfall rates for the East Asian coast during La Nina. The effect of ENSO on track propagation varies seasonally and spatially. In the peak activity season (July-October), there are significant changes in mean tracks with ENSO. Landfall-rate changes from genesis- and track-ENSO effects in the Philippines cancel out, while coastal segments of Vietnam, China, the Korean Peninsula, and Japan show enhanced La Nina-year increases.

  10. Evolution of the marketing theory: genesis, conception, periodization

    OpenAIRE

    M.A. Oklander; T.O. Oklander

    2016-01-01

    The aim of this article. The article deals with evolution of the marketing theory in it genesis context, modern conception, periodization. Mercantilism, classical and neoclassical political economy, marginalism, institutionalism are distinguished as scientific sources of marketing. One defines that modern marketing conception is a socially responsible marketing form, based on mass individualization, the highest customer value supply, consumer’s problems effective solving. The marketing theory...

  11. The genesis of collective health in Brazil.

    Science.gov (United States)

    Vieira-da-Silva, Ligia Maria; Pinell, Patrice

    2014-03-01

    During the 1970s in Brazil a social space directed towards health problems on the population level, called collective health, was created and institutionalised. To what extent did this Brazilian invention correspond to a specific socio-historical practice? The works published on this topic have considered social medicine as a homogeneous phenomenon without empirically studying the specificities of national experiences. To bridge this gap, a historical study on the genesis of collective health in Brazil was carried out based on Bourdieu's field theory. The interaction between the paths of the founders and the conditions of historical possibilities were researched through documentary and bibliographical sources, as well as through in-depth interviews of the founders. This social space originated from a meeting of agents with different social backgrounds but who interconnected, creating a structure that was independent of each agent considered individually. One of the components of this establishment was the joining of theoretical production and the implementation of health reforms that resulted in the organisation of a universal health system. This study attempts to show how the international political situation and the contradictions of the national crisis created a universe of possibilities, allowing for the genesis of this sui generis space in Brazil. © 2013 The Authors. Sociology of Health & Illness © 2013 Foundation for the Sociology of Health & Illness/John Wiley & Sons Ltd.

  12. Pristine Igneous Rocks and the Genesis of Early Planetary Crusts

    Science.gov (United States)

    Warren, Paul H.; Lindstrom, David (Technical Monitor)

    2002-01-01

    Our studies are highly interdisciplinary, but are focused on the processes and products of early planetary and asteroidal differentiation, especially the genesis of the ancient lunar crust. The compositional diversity that we explore is the residue of process diversity, which has strong relevance for comparative planetology.

  13. Paulus als Schriftuitlegger Paulus’ vertolking van Genesis 15:5b-6 in Romeinen 4:3

    Directory of Open Access Journals (Sweden)

    Pieter K. Baaij

    2005-07-01

      In this article the author illustrates that Paul in Romans 4:3 accurately renders what is written in Genesis 15:5b and 6. Paul teaches us to understand the Hebrew text better by indicating where the emphasis lies in the Hebrew text and how we must interpret the Hebrew terms used. For this reason Paul’s interpretation of Genesis 15:5b and 6 in Romans 4:3 is of great importance in the continually more topical debate on how we must translate the Bible.

  14. Tumour genesis syndrome: severe hypophosphatemia and hypokalemia may be ominous presenting findings in childhood acute myeloid leukaemia.

    Science.gov (United States)

    Chan, Winnie Ky; Chang, Kai On; Lau, Wing Hung

    2017-08-01

    We report a 16-year-old girl who was diagnosed with acute leukaemia and a marked leucocytosis >200 × 10 9 /L. She presented with marked hypophosphatemia, hypokalemia, acute renal failure and acute respiratory failure. These electrolytes disturbances may indicate rapid tumour genesis. These ominous findings required urgent treatment to halt the crises of rapid leukemic cell proliferation. Mark hypophosphatemia and hypokalemia may be presenting electrolyte abnormalities in a patient with acute leukaemia, and these may be indicators of aggressive tumour genesis. What is known: • Mild electrolyte disturbances are common in oncology patients • Tumour lysis syndrome is well recognized by paediatriaticians What is new: • Life-threatening hypophosphatemia is an uncommon presentation • These electrolytes disorders may indicate an aggressive tumour genesis process even at presentation and require urgent treatment.

  15. Shallow gas charged sediments off the Indian west coast: Genesis and distribution

    Digital Repository Service at National Institute of Oceanography (India)

    Mazumdar, A.; Peketi, A.; Dewangan, P.; Badesab, F.K.; Ramprasad, T; Ramana, M.V.; Patil, D.J.; Dayal, A.M.

    Geophysical and geochemical surveys were carried out off Goa, central west coast of India, to understand the genesis and distribution of shallow gases in marine sediments. Shallow gas charged sediments within the water depths of approx. 15 to 40 m...

  16. Die teologies-polemiese gerigtheid van Genesis 1-3: implikasies vir die gereformeerde leer oor die erfsonde

    Directory of Open Access Journals (Sweden)

    N. Vorster

    2009-07-01

    Full Text Available The theological polemic purpose of Genesis 1-3: implications for the reformed doctrine on original sin This article focuses on the polemic nature of Genesis 1-3 and the implications thereof on the reformed doctrine regarding original sin. In the first place the views of the creation narratives as historical-literal and mythological material are discussed. Thereafter the article proposes that the creation narratives must be treated as theological material with a polemic and prophetic purpose. The implications of this for the reformed doctrine on original sin are subsequently discussed.

  17. Luther's Lectures on Genesis 1:26-2:3

    DEFF Research Database (Denmark)

    Pedersen, Else Marie Wiberg

    2017-01-01

    This is a revised translation of Luther's Lectures on Genesis 1:26-2:3 (1535), drawn from Luther's Works, vol. 1, 55-82, but based on the Latin version of WA 42, 41-62. This revised translation is done with regard to inclusive language, and in this respect much closer to the Latin origin than...... to the English of the LW. I have added completely new annotations to explain Luther's theology as well as contetualize it, and chiefly new footnotes to explain the language and translations made....

  18. Genesis 2–3 and Alcibiades's speech in Plato's Symposium : A ...

    African Journals Online (AJOL)

    Genesis 2–3 and Alcibiades's speech in Plato's Symposium : A cultural critical reading. ... Abstract. The purpose of this article is to discuss some basic problems and methodological steps concerning the encounter between Hebrews and Greeks in the Classical period and its impact on the Hellenistic era. The relationship ...

  19. GENESIS OF METHODOLOGY OF MANAGEMENT BY DEVELOPMENT OF ORGANIZATIONS

    Directory of Open Access Journals (Sweden)

    Z.N. Varlamova

    2007-06-01

    Full Text Available In clause the genesis of methodology of management of development of organizations as sets of the used methodological approaches and methods is investigated. The results of the comparative analysis of the methodological approaches to management of organizational development are submitted. The traditional methodological approaches are complemented strategic experiment and methodology case studies. The approaches to formation of new methodology and technique of research of sources of competitive advantages of organization are considered.

  20. The instrumental genesis process in future primary teachers using Dynamic Geometry Software

    Science.gov (United States)

    Ruiz-López, Natalia

    2018-05-01

    This paper, which describes a study undertaken with pairs of future primary teachers using GeoGebra software to solve geometry problems, includes a brief literature review, the theoretical framework and methodology used. An analysis of the instrumental genesis process for a pair participating in the case study is also provided. This analysis addresses the techniques and types of dragging used, the obstacles to learning encountered, a description of the interaction between the pair and their interaction with the teacher, and the type of language used. Based on this analysis, possibilities and limitations of the instrumental genesis process are identified for the development of geometric competencies such as conjecture creation, property checking and problem researching. It is also suggested that the methodology used in the analysis of the problem solving process may be useful for those teachers and researchers who want to integrate Dynamic Geometry Software (DGS) in their classrooms.

  1. Re-interpreting Genesis 34 in the Light of Religious Violence in ...

    African Journals Online (AJOL)

    Religion plays significant roles in social harmony, yet it also serves as a motivation for violence. In Nigeria, religion has been at the centre of most violent conflicts, thereby gaining notoriety as one of the prime security challenges confronting the country. Genesis 34 is an important chapter in the Old Testament Bible.

  2. GENESIS 1.1: A hybrid-parallel molecular dynamics simulator with enhanced sampling algorithms on multiple computational platforms.

    Science.gov (United States)

    Kobayashi, Chigusa; Jung, Jaewoon; Matsunaga, Yasuhiro; Mori, Takaharu; Ando, Tadashi; Tamura, Koichi; Kamiya, Motoshi; Sugita, Yuji

    2017-09-30

    GENeralized-Ensemble SImulation System (GENESIS) is a software package for molecular dynamics (MD) simulation of biological systems. It is designed to extend limitations in system size and accessible time scale by adopting highly parallelized schemes and enhanced conformational sampling algorithms. In this new version, GENESIS 1.1, new functions and advanced algorithms have been added. The all-atom and coarse-grained potential energy functions used in AMBER and GROMACS packages now become available in addition to CHARMM energy functions. The performance of MD simulations has been greatly improved by further optimization, multiple time-step integration, and hybrid (CPU + GPU) computing. The string method and replica-exchange umbrella sampling with flexible collective variable choice are used for finding the minimum free-energy pathway and obtaining free-energy profiles for conformational changes of a macromolecule. These new features increase the usefulness and power of GENESIS for modeling and simulation in biological research. © 2017 Wiley Periodicals, Inc. © 2017 Wiley Periodicals, Inc.

  3. Education in the Knowledge Society: Genesis of Concept and Reality

    Science.gov (United States)

    Karpov, Alexander O.

    2016-01-01

    The aim of the article is to define the content of theoretical ideas about education in the knowledge society in terms of the birth of its social reality. It is shown that the genesis of the concept of education in the knowledge society goes back to the period of 1950-1960s and is due to the emergence of new qualities of an industrial worker that…

  4. Repliek op Van der Watt se artikel oor ‘Intertekstualiteit en oorinterpretasie: Verwysings na Genesis 28:12 in Johannes 1:51?’

    Directory of Open Access Journals (Sweden)

    Hennie F. Stander

    2017-10-01

    Full Text Available A response to Van der Watt’s article on ‘Intertextuality and over-interpretation: References to Genesis 28:12 in John 1:51?’ This article is a response to an article of Van der Watt titled ‘Intertextuality and over-interpretation: References to Genesis 28:12 in John 1:51?’ (2016. He states in this article that his aim is ‘to illustrate the dangers of over-interpretation when dealing with intertextual relations between texts, especially when allusion is assumed’. He then gives a brief survey of different interpretations of John 1:51. Van der Watt shows in his article how theologians use themes from Genesis 28:12 (like the ladder, Jacob or Bethel, which are not mentioned in John 1:51 in their expositions of John 1:51. Van der Watt regards some of these expositions as examples of over-interpretation. The aim of my article is to show how Church Fathers interpreted Genesis 28:12 and John 1:51. I show in my article that the Church Fathers saw several parallels between these two sections from the Bible. Furthermore, I suggest that the early theologians’ interpretations formed a tradition that probably influenced modern interpreters of the Bible. I also discuss the role of typology in the history of interpretation, specifically also in the case of Genesis 28:12 and John 1:51. I then argue that it is perhaps not so far-fetched to see an intertextual relation between Genesis 28:12 and John 1:51.

  5. Taking an Instrumental Genesis Lens: New Insights into Collaborative Mobile Learning

    Science.gov (United States)

    Cerratto Pargman, Teresa; Nouri, Jalal; Milrad, Marcelo

    2018-01-01

    In this paper, we argue that in order to gain a deeper understanding of collaborative mobile learning in schools, it is important to know not only how mobile devices affect collaborative learning but also how collaborative learning emerges and is mediated by these devices. We develop our argument by applying the instrumental genesis theory and the…

  6. NR2A contributes to genesis and propagation of cortical spreading depression in rats.

    Science.gov (United States)

    Bu, Fan; Du, Ruoxing; Li, Yi; Quinn, John P; Wang, Minyan

    2016-03-22

    Cortical spreading depression (CSD) is a transient propagating excitation of synaptic activity followed by depression, which is implicated in migraine. Increasing evidence points to an essential role of NR2A-containing NMDA receptors in CSD propagation in vitro; however, whether these receptors mediate CSD genesis in vivo requires clarification and the role of NR2A on CSD propagation is still under debate. Using in vivo CSD in rats with electrophysiology and in vitro CSD in chick retina with intrinsic optical imaging, we addressed the role of NR2A in CSD. We demonstrated that NVP-AAM077, a potent antagonist for NR2A-containing receptors, perfused through microdialysis probes, markedly reduced cortex susceptibility to CSD, but also reduced magnitude of CSD genesis in rats. Additionally, NVP-AAM077 at 0.3 nmol perfused into the contralateral ventricle, considerably suppressed the magnitude of CSD propagation wave and propagation rate in rats. This reduction in CSD propagation was also observed with TCN-201, a negative allosteric modulator selective for NR2A, at 3 μM, in the chick retina. Our data provides strong evidence that NR2A subunit contributes to CSD genesis and propagation, suggesting drugs selectively antagonizing NR2A-containing receptors might constitute a highly specific strategy treating CSD associated migraine with a likely better safety profile.

  7. PROFESSIONALISM: GENESIS AND CATEGORICAL ANALYSES

    Directory of Open Access Journals (Sweden)

    Ирина Олеговна Авдеева

    2013-12-01

    Full Text Available In the article the theoretical-methodological analysis of the concept of «professional», describes the genesis and key aspects of its content and structure. In addition, this publication discusses some of the approaches to the definition of the studied concepts, including: system (professional it seems as multipart strictly organized education of consciousness and psyche of the individual; professional graphic (from a position of objective (professional description and subjective (mental graph the parties; integrative (as property, process, and status of the person; acmeological (as the dialectical the unity of the personality and activity components; in terms of motivation and operating parties and other Stresses the importance of personal (theoretical knowledge, professional qualities, value orientations, motivational orientation of others and specific features of labour employee (practical skills, professional experience and other, determining the effectiveness of its activities.DOI: http://dx.doi.org/10.12731/2218-7405-2013-10-12

  8. Design and descriptive results of the "Growth, Exercise and Nutrition Epidemiological Study In preSchoolers": The GENESIS Study

    Directory of Open Access Journals (Sweden)

    Manios Yannis

    2006-02-01

    Full Text Available Abstract Background The Growth, Exercise and Nutrition Epidemiological Study in preSchoolers (GENESIS attempts to evaluate the food and nutrient intakes, as well as growth and development of a representative sample of Greek toddlers and preschool children. In the current work the study design, data collection procedures and some preliminary data of the GENESIS study are presented. Methods From April 2003 to July 2004, 1218 males and 1156 females 1 to 5 years old, stratified by parental educational level (Census 1999, were examined from 105 nurseries in five counties. Approximately 300 demographic, lifestyle, physical activity, dietary, anthropometrical and DNA variables have been recorded from the study population (children and parents. Results Regarding anthropometrical indices, boys were found to be taller than girls at all ages (P Conclusion The prevalence of overweight in the current preschool population is considerably high. Future but more extensive analyses of the GENESIS data will be able to reveal the interactions of the parameters leading to this phenomenon.

  9. Multi-element RIMS Analysis of Genesis Solar Wind Collectors

    Science.gov (United States)

    Veryovkin, I. V.; Tripa, C. E.; Zinovev, A. V.; King, B. V.; Pellin, M. J.; Burnett, D. S.

    2009-12-01

    The samples of Solar Wind (SW) delivered by the NASA Genesis mission, present significant challenges for surface analytical techniques, in part due to severe terrestrial contamination of the samples on reentry, in part due to the ultra-shallow and diffused ion implants in the SW collector materials. We are performing measurements of metallic elements in the Genesis collectors using Resonance Ionization Mass Spectrometry (RIMS), an ultra-sensitive analytical method capable of detecting SW in samples with lateral dimensions of only a few mm and at concentrations from above one ppm to below one ppt. Since our last report at 2008 AGU Fall Meeting, we have (a) developed and tested new resonance ionization schemes permitting simultaneous measurements of up to three (Ca, Cr, and Mg) elements, and (b) improved reproducibility and accuracy of our RIMS analyses for SW-like samples (i.e. shallow ion implants) by developing and implementing an optimized set of new analytical protocols. This is important since the quality of scientific results from the Genesis mission critically depends on the accuracy of analytical techniques. In this work, we report on simultaneous RIMS measurements of Ca and Cr performed on two silicon SW collector samples, (#60179 and #60476). First, we have conducted test experiments with 3×1013 at/cm2 52Cr and 44Ca implants in silicon to evaluate the accuracy of our quantitative analyses. Implant fluencies were measured by RIMS to be 2.73×1013 and 2.71×1013 at/cm2 for 52Cr and 44Ca, respectively, which corresponds to an accuracy of ≈10%. Using the same implanted wafer as a reference, we conducted RIMS analyses of the Genesis samples: 3 spots on #60179 and 4 spots on #60476. The elemental SW fluencies expected for Cr and Ca are 2.95×1010 and 1.33×1011 at/cm2 , respectively. Our measurements of 52Cr yielded 3.0±0.6×1011 at/cm2 and 5.1±4.1×1010 at/cm2 for #60179 and #60476, respectively. For 40Ca, SW fluencies of 1.39±0.70×1011 at/cm2 in #60179

  10. Genesis of iron-apatite ores in Posht-e-Badam Block (Central Iran ...

    Indian Academy of Sciences (India)

    Central Iran; iron-apatite ore; Kiruna-type; Posht-e-Badam Block; REE geochemistry. J. Earth Syst ... ferent ore genesis models have been proposed for ...... volatile-rich magma systems stress the important .... Laco magnetite flow deposits, northern Chile: An up-to- ... economic report on iron ore prevision of the Esfahan steel.

  11. Can micro-PIXE measurements help to determine ore genesis ?

    International Nuclear Information System (INIS)

    Ahmed, M.; Al-Ohali, M.A.

    2002-01-01

    This study is an attempt to demonstrate how the nuclear micro-PIXE technique can be utilized to investigate ore genesis of geological deposits. Elemental concentrations and distribution profiles in single mineral grains and matrices in a present-day ore deposit on land were measured using the scanning proton microprobe on the 3 MV Tandetron accelerator at King Fahd University of Petroleum and Minerals. Comparing the distribution profiles of some of the trace elements detected it was possible to suggest an organic, sea origin of these deposits. (Author)

  12. The Instrumental Genesis Process in Future Primary Teachers Using Dynamic Geometry Software

    Science.gov (United States)

    Ruiz-López, Natalia

    2018-01-01

    This paper, which describes a study undertaken with pairs of future primary teachers using GeoGebra software to solve geometry problems, includes a brief literature review, the theoretical framework and methodology used. An analysis of the instrumental genesis process for a pair participating in the case study is also provided. This analysis…

  13. Modelling the genesis of equatorial podzols: age and implications for carbon fluxes

    Science.gov (United States)

    Doupoux, Cédric; Merdy, Patricia; Régina Montes, Célia; Nunan, Naoise; José Melfi, Adolpho; José Ribeiro Pereira, Osvaldo; Lucas, Yves

    2017-05-01

    Amazonian podzols store huge amounts of carbon and play a key role in transferring organic matter to the Amazon River. In order to better understand their C dynamics, we modelled the formation of representative Amazonian podzol profiles by constraining both total carbon and radiocarbon. We determined the relationships between total carbon and radiocarbon in organic C pools numerically by setting constant C and 14C inputs over time. The model was an effective tool for determining the order of magnitude of the carbon fluxes and the time of genesis of the main carbon-containing horizons, i.e. the topsoil and deep Bh. We performed retrocalculations to take into account the bomb carbon in the young topsoil horizons (calculated apparent 14C age from 62 to 109 years). We modelled four profiles representative of Amazonian podzols, two profiles with an old Bh (calculated apparent 14C age 6.8 × 103 and 8.4 × 103 years) and two profiles with a very old Bh (calculated apparent 14C age 23.2 × 103 and 25.1 × 103 years). The calculated fluxes from the topsoil to the perched water table indicate that the most waterlogged zones of the podzolized areas are the main source of dissolved organic matter found in the river network. It was necessary to consider two Bh carbon pools to accurately represent the carbon fluxes leaving the Bh as observed in previous studies. We found that the genesis time of the studied soils was necessarily longer than 15 × 103 and 130 × 103 years for the two younger and two older Bhs, respectively, and that the genesis time calculated considering the more likely settings runs to around 15 × 103-25 × 103 and 150 × 103-250 × 103 years, respectively.

  14. The Genesis of Romanian Football. Social Factors and Processes behind the Game

    Directory of Open Access Journals (Sweden)

    PÉTER, László

    2014-12-01

    Full Text Available The present article deals with those social and economic factors that contributed to the genesis of Romanian soccer at the turn of the previous century. The author argues that football was imported from abroad via peregrination and schools, but certain social processes, such as urbanization, capitalization and the appearance of massive working classes, are the reasons why this beautiful game became socially embedded in the local environments. The different circumstances in Banat and Transylvania and in the old Romanian Kingdom marked the social history and trajectory “travelled” by the ball. While in the western part of the country, football arrived in a fertile ground because of the already existing bourgeois sport associations and the rapidly emerging local working classes, the role of foreign companies and expats in implementing football was more significant in the southern regions. This difference in the genesis of the game produced two distinct styles of playing football. These two styles clearly reflect the historical and social background specific to the different regions.

  15. Enhanced Cleaning of Genesis Solar Wind Sample 61348 for Film Residue Removal

    Science.gov (United States)

    Allums, K. K.; Gonzalez, C. P.; Kuhlman, K. R.; Allton, J. H.

    2015-01-01

    The Genesis mission returned to Earth on September 8, 2004, experiencing a nonnominal reentry. During the recovery of the collector materials from the capsule, many of the collector fragments were placed on the adhesive protion of post-it notes to prevent the fragments from moving during transport back to Johnson Space Center. This unknowingly provided an additional contaminate that would prove difficult to remove with the limited chemistries allowed in the Genesis Curation Laboratory. Generally when collector material samples are prepared for allocation to PIs, the samples are cleaned front side only with Ultra-Pure Water (UPW) via megasonic dispersion to the collector surface to remove crash debris and contamination. While this cleaning method works well on samples that were not placed on post-its during recovery, it has caused movement of the residue on the back of the sample to be deposited on the front in at least two examples. Therefore, samples placed on the adhesive portion on post-it note, require enhanced cleaning methods since post-it residue has proved resistant to UPW cleaning.

  16. Interdecadal Change of Tropical Cyclone Genesis Controlling Parameter in Western North Pacific

    Science.gov (United States)

    Li, T.

    2017-12-01

    The main environmental parameter controlling tropical cyclone (TC) genesis in the western North Pacific (WNP) changed in different interdecadal periods. The interannual variability of TC genesis frequency was primarily control by specific humidity in 1950-1976, sea surface temperature (SST) in 1977-1998, and vorticity in 1999-2014. A further diagnosis shows that the change of environmental specific humidity during 1950-1976 was attributed to anomalous advection of mean moisture during ENSO developing summer. The SST change during 1977-1998 was associated with circulation change during ENSO decaying summer. The change of environment vorticity was primarily related to CP-type El Niño during 1999-2014. The ultimate cause of the controlling parameter change is attributed to the change of ENSO behavior. Compared to the first period, a stronger EP-type ENSO variability in the second period leads to a stronger circulation/SST response during ENSO decaying phase. The occurrence of more frequent CP type El Niño in the third period was responsible for greater vorticity controlling in the WNP.

  17. On the genesis of pyrite-polymetallic deposits of the Rudnyi Altai

    International Nuclear Information System (INIS)

    Puchkov, E.V.; Najdenov, B.M.

    1986-01-01

    Results of lead isotope composition measurements in pyrite-polymetallic deposits of the Rudnyi Altai are presented. Porphyr dating by zirconium has shown isochronous age of 552 million years. Lead of galenites of various generations and galenite form of lead of pyrit provide similar lead-isotope values with model age of 370 million years. The isotopic-geochemical data obtained are interpreted as applied to the deposit genesis

  18. Dynamics and Predictability of Tropical Cyclone Genesis, Structure and Intensity Change

    Science.gov (United States)

    2012-09-30

    analyses and forecasts of tropical cyclones, including genesis, intensity change, and extratropical transition. A secondary objective is to understand... storm -centered assimilation algorithm. Basic research in Report Documentation Page Form ApprovedOMB No. 0704-0188 Public reporting burden for the...COMPLETED For the four storms consider (Nuri, Jangmi, Sinlaku, and Hagupit), an 80-member EnKF has been cycled on observations (surface, rawinsondes, GPS

  19. MINING LAKES OF THE AGHIREŞ AREA: GENESIS, EVOLUTION AND MORPHOMETRIC ASPECTS

    Directory of Open Access Journals (Sweden)

    V. MĂCICĂŞAN

    2012-03-01

    Full Text Available Mining lakes of the Aghireş area: Genesis, evolution and morphometric aspects. Mining activities are heavily influencing and destroying the landscape worldwide. In Aghireş mining perimeter, exploitation workings have led to extreme and irreversible environmental damages, especially regarding the geomorphologic and hydrological situation. After cessation of underground mining and initiation of quarry exploitation, certain mining galleries collapsed and were afterwards flooded by precipitation and re-ascending groundwater, leading to the formation of lacustrine units. Later, the abandoned quarries have undergone the same flooding process. In this paper, we report on the genesis, evolution and the current characteristics of these bodies of water, referred to as mining lakes. In addition, using the GIS technology, the morphometry of the mining lakes is presented in this paper. Due to their predominant current use, as for recreational purposes, the sustainable management of the mining lakes is an important ecological and socio-economical factor for the Aghireş area. For the majority of mining lakes, restoration measures may be necessary due to the demands of the European legislation as well as to the demands of a specific socio-economic use in the future (e.g. bathing lakes or fishing lakes. These aspects of investigation will constitute a prerequisite for effective environmental management and rehabilitation strategies.

  20. Basement to surface expressions and critical factors in the genesis of unconformity-related deposits

    International Nuclear Information System (INIS)

    Potter, Eric

    2014-01-01

    Two subprojects: 1) Basement to surface expressions of deep mineralization and refinement of critical factors leading to the genesis of unconformity-related uranium deposits; and 2) Recognition of uranium ore system alteration signatures in complex terranes: IOCG vs albite-hosted uranium vs volcanic-hosted uranium.

  1. A climatological model of North Indian Ocean tropical cyclone genesis, tracks and landfall

    Science.gov (United States)

    Wahiduzzaman, Mohammad; Oliver, Eric C. J.; Wotherspoon, Simon J.; Holbrook, Neil J.

    2017-10-01

    Extensive damage and loss of life can be caused by tropical cyclones (TCs) that make landfall. Modelling of TC landfall probability is beneficial to insurance/re-insurance companies, decision makers, government policy and planning, and residents in coastal areas. In this study, we develop a climatological model of tropical cyclone genesis, tracks and landfall for North Indian Ocean (NIO) rim countries based on kernel density estimation, a generalised additive model (GAM) including an Euler integration step, and landfall detection using a country mask approach. Using a 35-year record (1979-2013) of tropical cyclone track observations from the Joint Typhoon Warning Centre (part of the International Best Track Archive Climate Stewardship Version 6), the GAM is fitted to the observed cyclone track velocities as a smooth function of location in each season. The distribution of cyclone genesis points is approximated by kernel density estimation. The model simulated TCs are randomly selected from the fitted kernel (TC genesis), and the cyclone paths (TC tracks), represented by the GAM together with the application of stochastic innovations at each step, are simulated to generate a suite of NIO rim landfall statistics. Three hindcast validation methods are applied to evaluate the integrity of the model. First, leave-one-out cross validation is applied whereby the country of landfall is determined by the majority vote (considering the location by only highest percentage of landfall) from the simulated tracks. Second, the probability distribution of simulated landfall is evaluated against the observed landfall. Third, the distances between the point of observed landfall and simulated landfall are compared and quantified. Overall, the model shows very good cross-validated hindcast skill of modelled landfalling cyclones against observations in each of the NIO tropical cyclone seasons and for most NIO rim countries, with only a relatively small difference in the percentage of

  2. About estimation of the contamination of territorial-administrative regions of the Chernobyl genesis radionuclides

    International Nuclear Information System (INIS)

    Berezhnoj, A.V.

    2005-01-01

    It is recommended to realize the matching territorial-administrative regions on degree of the contamination their of the Chernobyl genesis radionuclides to size generalised index gravity of the radionuclide soiling region. The methodology of the calculation indexes is offered. The results executed estimation are briefly stated. (authors)

  3. Large-Scale Influences on the Genesis of Tropical Cyclone Karl (2010)

    Science.gov (United States)

    Griffin, K.; Bosart, L. F.

    2012-12-01

    The events leading up to the genesis of Tropical Cyclone (TC) Karl (2010) provides a unique opportunity to examine the continuing problem of understanding tropical cyclogenesis. The PRE-Depression Investigation of Cloud-systems in the Tropics (PREDICT) field campaign allowed for detailed investigation of the tropical disturbance that served as the precursor to TC Karl as it progressed westward through the Caribbean Sea. The purpose of this presentation is to examine the evolution of the pre-Karl disturbance using both common synoptic-scale analyses as well as statistically-based equatorial wave analyses, focusing on where these analyses complement and enhance each other. One of the major factors in the initial spin-up of the pre-Karl tropical disturbance is a surge of southerly and westerly winds from northern South America on 8-10 September 2010. As the surge entered the Caribbean on 9 September, it aided in the formation of a nearly closed earth-relative cyclonic circulation near the southern Leeward Islands. This circulation weakened late on 10 September and remained weak through 13 September before increased organization led to TC genesis on 14 September. This southerly wind surge can be traced to a well-defined surge of anomalously cold air and enhanced southerly winds originating in the lee of the Argentinian Andes over a week prior. While the temperature anomalies wash out prior to reaching the equator, anomalous low-level winds progress into Colombia and Venezuela, where topography aids in turning the southerly winds eastward. An investigation of the pre-Karl environment utilizing wavenumber-frequency filtering techniques also suggests that the initial spin-up of pre-Karl can be associated with the active phase of a convectively coupled Kelvin wave (CCKW). The observed formation of the nearly closed cyclonic circulation on 10 September is well timed with the passage of anomalous westerly winds along and behind the convectively active phase of a CCKW. These

  4. GENESIS: a hybrid-parallel and multi-scale molecular dynamics simulator with enhanced sampling algorithms for biomolecular and cellular simulations.

    Science.gov (United States)

    Jung, Jaewoon; Mori, Takaharu; Kobayashi, Chigusa; Matsunaga, Yasuhiro; Yoda, Takao; Feig, Michael; Sugita, Yuji

    2015-07-01

    GENESIS (Generalized-Ensemble Simulation System) is a new software package for molecular dynamics (MD) simulations of macromolecules. It has two MD simulators, called ATDYN and SPDYN. ATDYN is parallelized based on an atomic decomposition algorithm for the simulations of all-atom force-field models as well as coarse-grained Go-like models. SPDYN is highly parallelized based on a domain decomposition scheme, allowing large-scale MD simulations on supercomputers. Hybrid schemes combining OpenMP and MPI are used in both simulators to target modern multicore computer architectures. Key advantages of GENESIS are (1) the highly parallel performance of SPDYN for very large biological systems consisting of more than one million atoms and (2) the availability of various REMD algorithms (T-REMD, REUS, multi-dimensional REMD for both all-atom and Go-like models under the NVT, NPT, NPAT, and NPγT ensembles). The former is achieved by a combination of the midpoint cell method and the efficient three-dimensional Fast Fourier Transform algorithm, where the domain decomposition space is shared in real-space and reciprocal-space calculations. Other features in SPDYN, such as avoiding concurrent memory access, reducing communication times, and usage of parallel input/output files, also contribute to the performance. We show the REMD simulation results of a mixed (POPC/DMPC) lipid bilayer as a real application using GENESIS. GENESIS is released as free software under the GPLv2 licence and can be easily modified for the development of new algorithms and molecular models. WIREs Comput Mol Sci 2015, 5:310-323. doi: 10.1002/wcms.1220.

  5. Audio-magnetotelluric (AMT) study to investigate the genesis of Mujil hill

    Science.gov (United States)

    Rahmania, Suryanto, Wiwit

    2017-07-01

    Gunung Mujil is an isolated hill located near Pondoworejo village, Kalibawang sub-district, Kulon Progo district, and Special Province of Yogyakarta. The hill is part of the eastern Kulon Progo mountain range extended relatively in the North-South direction. The lithology of the hill consists of andesite breccia and it's similar with the Old Andesite Formation that built the Kulon Progo Mountains. There are at least two hypothesis about the genesis and the formation mechanism of this hill, (1) it was formed by debris mass from Kulon Progo Mountains, and (2) ) it was formed by an intrusion. Our study intended to determine the subsurface resistivity below the hill and to relating those results to with the scenario of the genesis of the Mujil hill. We conducted Audio-magnetotellurics (AMT) measurements along two lines survey crossing the Mujil hill consisting of 20 measurements. Since the measurements are located near the villages, most of the data has a fair to bad quality and only one station yielded an excellent data. A 1D Forward modeling was then applied to find best-fit model of the AMT data. The results shows that the Mujil hill was built by debris mass of the Old Andesite Formation from Kulon Progo mountain which is represented by a lower resistivity value under the Mujil hill.

  6. Genesis of the Brazilian nuclear power plants program

    International Nuclear Information System (INIS)

    Syllus, G.; Lepecki, W.

    1996-01-01

    The genesis of the Brazilian Nuclear Power Program is described by the authors - who participated in the events - from the beginning of the sixties, until the definition and the start of the implementation in 1975 of the Reference Nuclear Power Program. A description is made of the main events, studies and decisions that contributed to the evolution of the Program: the GTRP (Nuclear Power Plant Working Group); the Thorium Group; the Lane Group; the decision about Angra 1; CNEN's analyses about the reactor line and, finally, the creation of CBTN (Nuclear Technology Brazilian Company), which elaborated the studies that resulted in the final definition of the Program and led to the Brazilian German Agreement and the establishment of NUCLEBRAS. (author)

  7. PSYCHOANALYTIC INTERPRETATION OF JUSTICE IN CONTEXT OF PROBLEMS OF TECHNO-GENESIS (Part II

    Directory of Open Access Journals (Sweden)

    N. I. Mushinskij

    2009-01-01

    Full Text Available Carl Gustav Jung, Erich Fromm, Karen Horney, Jacques Lacan, Gilles Deleuze, Felix Guattari continue to develop a psychoanalytic theory of Freud under modern conditions. They investigate archetypes of unconscious which are linked with up-to-date conception of Justice. Ethics of psychoanalysis interprets the category of Justice from humanistic positions in the context of the techno-genesis processes.

  8. DETERMINING THE ELEMENTAL AND ISOTOPIC COMPOSITION OF THE PRESOLAR NEBULA FROM GENESIS DATA ANALYSIS: THE CASE OF OXYGEN.

    Science.gov (United States)

    Laming, J Martin; Heber, V S; Burnett, D S; Guan, Y; Hervig, R; Huss, G R; Jurewicz, A J G; Koeman-Shields, E C; McKeegan, K D; Nittler, L; Reisenfeld, D B; Rieck, K D; Wang, J; Wiens, R C; Woolum, D S

    2017-12-10

    We compare element and isotopic fractionations measured in solar wind samples collected by NASA's Genesis mission with those predicted from models incorporating both the ponderomotive force in the chromosphere and conservation of the first adiabatic invariant in the low corona. Generally good agreement is found, suggesting that these factors are consistent with the process of solar wind fractionation. Based on bulk wind measurements, we also consider in more detail the isotopic and elemental abundances of O. We find mild support for an O abundance in the range 8.75 - 8.83, with a value as low as 8.69 disfavored. A stronger conclusion must await solar wind regime specific measurements from the Genesis samples.

  9. Three Proposed Compendia for Genesis Solar Wind Samples: Science Results, Collector Materials Characterization and Cleaning Techniques

    Science.gov (United States)

    Allton, J. H.; Calaway, M. J.; Nyquist, L. E.; Jurewicz, A. J. G.; Burnett, D. S.

    2018-01-01

    Final Paper and not the abstract is attached. Introduction: Planetary material and cosmochemistry research using Genesis solar wind samples (including the development and implementation of cleaning and analytical techniques) has matured sufficiently that compilations on several topics, if made publically accessible, would be beneficial for researchers and reviewers. We propose here three compendia based on content, organization and source of documents (e.g. published peer-reviewed, published, internal memos, archives). For planning purposes, suggestions are solicited from potential users of Genesis solar wind samples for the type of science content and/or organizational style that would be most useful to them. These compendia are proposed as living documents, periodically updated. Similar to the existing compendia described below, the curation compendia are like library or archival finding aids, they are guides to published or archival documents and should not be cited as primary sources.

  10. NONINVASIVE NASAL MUCOSA EXPOSURE TO TREAT AND PREVENT RHINITIS AND RHINOSINUSITIS OF VARIOUS GENESIS

    Directory of Open Access Journals (Sweden)

    E. Yu. Radtsig

    2014-07-01

    Full Text Available The paper deals with the evaluation of the nasal mucosa in health and in different abnormalities. It describes the possibilities of using drugs of different groups to relieve symptoms in nasal mucosal and paranasal sinus abnormalities of different genesis, as well as the preventive effect of some of these drugs.

  11. A mouse model for monitoring islet cell genesis and developing therapies for diabetes

    Directory of Open Access Journals (Sweden)

    Yoshinori Shimajiri

    2011-03-01

    Transient expression of the transcription factor neurogenin-3 marks progenitor cells in the pancreas as they differentiate into islet cells. We developed a transgenic mouse line in which the surrogate markers secreted alkaline phosphatase (SeAP and enhanced green florescent protein (EGFP can be used to monitor neurogenin-3 expression, and thus islet cell genesis. In transgenic embryos, cells expressing EGFP lined the pancreatic ducts. SeAP was readily detectable in embryos, in the media of cultured embryonic pancreases and in the serum of adult animals. Treatment with the γ-secretase inhibitor DAPT, which blocks Notch signaling, enhanced SeAP secretion rates and increased the number of EGFP-expressing cells as assayed by fluorescence-activated cell sorting (FACS and immunohistochemistry in cultured pancreases from embryos at embryonic day 11.5, but not in pancreases harvested 1 day later. By contrast, treatment with growth differentiation factor 11 (GDF11 reduced SeAP secretion rates. In adult mice, partial pancreatectomy decreased, whereas duct ligation increased, circulating SeAP levels. This model will be useful for studying signals involved in islet cell genesis in vivo and developing therapies that induce this process.

  12. The impact of Saharan Dust on the genesis and evolution of Hurricane Earl (2010)

    Science.gov (United States)

    Pan, B.; Wang, Y.; Hsieh, J. S.; Lin, Y.; Hu, J.; Zhang, R.

    2017-12-01

    Dust, one of the most abundant natural aerosols, can exert substantial radiative and microphysical effects on the regional climate and has potential impacts on the genesis and intensification of tropical cyclones (TCs). A Weather Research and Forecasting Model and the Regional Oceanic Modeling System coupled model (WRF-ROMS) is used to simulate the evolution of Hurricane Earl (2010), of which Earl was interfered by Saharan dust at the TC genesis stage. A new dust module has been implemented to the TAMU two-moment microphysics scheme in the WRF model. It accounts for both dust as Cloud Condensation Nuclei (CCN) and Ice Nuclei (IN). The hurricane track, intensity and precipitation have been compared to the best track data and TRMM precipitation, respectively. The influences of Saharan dust on Hurricane Earl are investigated with dust-CCN, dust-IN, and dust-free scenarios. The analysis shows that Saharan dust changes the latent heat and moisture distribution, invigorates the convections in the hurricane's eyewall, and suppresses the development of Earl. This finding addresses the importance of accounting dust microphysics effect on hurricane predictions.

  13. Fullerene genesis by ion beams

    International Nuclear Information System (INIS)

    Gamaly, E.G.; Chadderton, L.T.; Commonwealth Scientific and Industrial Research Organization, Lindfield, NSW

    1995-01-01

    Clearly detectable quantities of molecular fullerene (C 60 ), the most recently discovered allotrope of carbon, have been observed in graphite following irradiation with heavy projectile ions at energies of about 1 GeV using high pressure chromatography. Similar experiments using lower ion energies gave no corresponding signal, indicating an absence of fullerene. This clear difference suggests that there exists an energy threshold for fullerene genesis. Beginning with a microscopic description of deposition and transfer of energy from the ion to the target, a theoretical model is developed for interpretation of these and similar experiments. An important consequence is a description of the formation of large carbon clusters in the hot dense 'primeval soup' of single carbon atoms by means of random 'sticky' collisions. The ion energy threshold is seen as arising, physically, from a balance in the competition between the rate of primary energy deposition and the rate of system cooling. Rate equations for the basic clustering process allow calculations of the time-dependent number densities for the different carbon clusters produced. An important consequence of the theory is that it is established that the region for the specific phase transition from graphite to fullerene lies in the same pressure regime on the phase diagram as does the corresponding transition for graphite to diamond. (author)

  14. Marguerite Duras/Claude Régy: L’Amante Anglaise, the genesis of a text, the gestation of a theatre

    Directory of Open Access Journals (Sweden)

    Almuth Grésillon

    2013-07-01

    Full Text Available This article focuses on the genesis of the first staging of Margerite Duras’s L’Amante Anglaise, by Claude Régy, a well succeeded genesis, carried out based on the interplay between dramaturgy and the stage. Without any satisfying answer, we are facing an important theoretical issue of genetic criticism applied to theatre: is the work a dramatic text or a spectacle? Depending on the stress on the first or on the second answer, the organizing axis of the genetic dossier can be the author’s writing and all stagings of L’Amante Anglaise,forming a theoretically unified set; or the director’s notes and all of his creations. This study explores a third possibility, stipulating the indispensable intersection between both hypotheses.

  15. The genesis of fluid mechanics, 1640-1780

    CERN Document Server

    Calero, Julián Simón

    2008-01-01

    Fluid Mechanics, as a scientific discipline in a modern sense, was established between the last third of the 17th century and the first half of the 18th one. This book analyses its genesis, following its evolution along two basic lines of research, which have been named the "problem of resistance" and the "problem of discharge". This approach highlights the existence of a remarkable experimental aspect in the aforementioned research lines, together with their link with problems of a practical nature, such as ballistics, hydraulics, fluid-using machines or naval theory. On the other hand, although previous studies usually present fluid mechanics from the point of view of mathematics, this is complemented here by an engineering viewpoint; gathering attempts made in the beginnings of fluid mechanics to see if the theory was capable of productive application in practical terms. This is nothing unusual in a time where the quality of knowledge and skill is measured largely by its usefulness. (c) Universidad Naciona...

  16. The impact of summertime north Indian Ocean SST on tropical cyclone genesis over the western North Pacific

    Science.gov (United States)

    Zheng, Jiayu; Wu, Qiaoyan; Guo, Yipeng; Zhao, Sen

    2017-04-01

    In this study, we investigate the impact of interannual variability of boreal summertime (June-September) north Indian Ocean (NIO) sea surface temperature (SST) on the distribution of tropical cyclone (TC) genesis over the western North Pacific (WNP) using observational datasets. In the boreal summers with warm (cold) SST in the NIO, fewer (more) than normal TCs form over the entire WNP, with fewer (more) TCs forming north of 10°N and more (fewer) TCs forming south of 10°N. The warm (cold) SST in the NIO induces anomalous anticyclonic (cyclonic) vorticity north of 10°N and cyclonic (anticyclonic) vorticity south of 10°N, which contributes to the meridional seesaw-like distribution of WNP TC genesis. This study provides a new perspective to understand TC activities over the WNP and may help seasonal TC prediction.

  17. Genealogies and spiritualities in Genesis 4:17-22, 4:25-26, 5:1-32 ...

    African Journals Online (AJOL)

    The three genealogies in Genesis 4:17-22, 4:25-26 en 5:1-32 show different intentions: the first wants (amongst other purposes) to give an aetiology of the trades; the second wants to stress the importance of a new beginning; the third wants to relate Adam to Noah. Each of these approaches to genealogy has a different ...

  18. Adam. Příběh prvního člověka v knize Genesis a v Koránu

    Directory of Open Access Journals (Sweden)

    Mlada Mikulicová

    2014-10-01

    Full Text Available In both books Adam is presented as a prototypical man created from physical elements and endowed with divine inspiration that makes him capable of rational actions. While Genesis narrates the story of Adam from his creation to his death, stressing chronology and future development in history, the Qur’an’s rendering is fragmentary. Of vast underlying popular traditions on Adam and Eve, Genesis previews the history of God’s covenant and salvific action towards humankind while the Qur’an persists on the theme of human disobedience and God’s absolute governance. Despite common themes as the createdness of man, his superiority over the rest of the creation, the complementary nature of human being as man and woman, the loss of happiness through disobedience to God’s law, the two stories differ in interpretation. While the acceptance of evil into human heart is reflected as voluntary in Genesis, the Qur’an finds excuse in the revolt of Satan who is shown in a more active role than man. Eliminating the notions of man as the image of God, and the final abolishment of evil, the Qur’an uses Adam’s story to demonstrate the principal axioms of Islamic doctrine: God must be obeyed and Satan’s lures avoided else man will not attain the Garden; Adam is a prototypal prophet, informing of these truths. Adam and Eve, according to the narration of the Book of Genesis, represent human existence in the drama of knowing evil and distress, hiding from God, and hearing his promise of future salvation that begins to unroll in their progeny. V biblicke knize Genesis i v Koranu je Adam představen jako prototyp člověka stvořeneho z fyzickych prvků a „Božiho vdechnuti“ racionality. Biblicke vypravěni je chronologicky přiběh, Koran zmiňuje pouze některe časti sparsatim v deseti různych surach. Genesis jakožto prolog k biblickemu celku vybira tradični latky k dokumentaci Božich dějin spasy, zatimco Koran eliminuje všechno, co nesouvisi

  19. Landscape formation and soil genesis in volcanic parent materials in humid tropical lowlands of Costa Rica

    NARCIS (Netherlands)

    Nieuwenhuyse, A.

    1996-01-01


    The influence of volcanism on landscape genesis, and formation of soils on volcanic parent material was studied in the Atlantic lowland of Costs Rica. This lowland is a subduction basin of tectonic origin, in which thick alluvial and marine sediments are accumulated. At its southwestern

  20. Improvement of orthopedic dental treatment of patients suffering post-surgery defects of the maxilla of cancer genesis

    Directory of Open Access Journals (Sweden)

    A. S. Arutyunov

    2015-01-01

    Full Text Available The paper presents a comprehensive study identifying the key issuesand giving the mathematical, and clinical and microbiological substantiation of modern principles of providing orthopedic dental care to patients with acquired defects of the upper jaw of cancer genesis.

  1. Helium, neon, and argon composition of the solar wind as recorded in gold and other Genesis collector materials

    Science.gov (United States)

    Pepin, Robert O.; Schlutter, Dennis J.; Becker, Richard H.; Reisenfeld, Daniel B.

    2012-07-01

    We report compositions and fluxes of light noble gases in the solar wind (SW), extracted by stepped pyrolysis and amalgamation from gold collector materials carried on the Genesis Solar Wind Sample Return Mission. Results are compared with data from other laboratories on SW-He, Ne and Ar distributions implanted in Genesis aluminum, carbon, and silicon collectors and extracted by laser ablation. Corrections for mass-dependent losses (“backscatter”) of impinging SW ions due to scattering from the collector material are substantially larger for gold than for these lower atomic weight targets. We assess such losses by SRIM simulation calculations of SW backscatter from gold which are applied to the measurements to recover the composition of the incident SW. Averaged results of integrated stepped pyrolysis and single-step amalgamation measurements, with 1σ errors, are as follows: for SW-Ne and Ar isotope ratios (3He/4He was not measured), 20Ne/22Ne = 14.001 ± 0.042, 21Ne/22Ne = 0.03361 ± 0.00018, 36Ar/38Ar = 5.501 ± 0.014; for SW element ratios, 4He/20Ne = 641 ± 15, 20Ne/36Ar = 51.6 ± 0.5; and for SW fluxes in atoms cm-2 s-1 at the Genesis L1 station, 4He = 1.14 ± 0.04 × 107, 20Ne = 1.80 ± 0.06 × 104, 36Ar = 3.58 ± 0.11 × 102. Except for the 21Ne/22Ne and 20Ne/36Ar ratios, these values are in reasonable accord (within ∼1-3σ) with measurements on different collector materials reported by one or both of two other Genesis noble gas research groups. We further find, in three stepped pyrolysis experiments on gold foil, that He, Ne and Ar are released at increasing temperatures without elemental fractionation, in contrast to a pyrolytic extraction of a single non-gold collector (Al) where the release patterns point to mass-dependent thermal diffusion. The pyrolyzed gold foils exhibit enhancements, relative to sample totals, in 20Ne/22Ne and 21Ne/22Ne ratios evolved at low temperatures. The absence of elemental fractionation in pyrolytic release from gold

  2. Implication of neuro-genesis during brain development in behavior disorders caused by depleted uranium

    International Nuclear Information System (INIS)

    Legrand, Marie

    2016-01-01

    Humans are continuously exposed to neurotoxic compounds in the environment. The developing brain is more susceptible to neurotoxic compounds and modifications in its growth could lead to disorders in adulthood. Uranium (U) is an environmental heavy metal and induces behavioral disorders as well as affects neurochemistry. The aim of my thesis was to investigate whether depleted uranium (DU) exposure affects neuro-genesis processes, which are implicated in brain development and in synaptic plasticity in adults. While DU increased cell proliferation in the hippocampal neuro-epithelium and decreased cell death at prenatal stages, DU lead to opposite effects in the dentate gyrus at postnatal stages. Moreover, DU had an inhibitory effect on the transition toward neuronal differentiation pathway during development. At adult stage, DU induced a decrease in neuronal differentiation but has no impact in cell proliferation. Finally, DU exposure during brain development caused depressive like behavior at late postnatal and adult stage, and decreased spatial memory at adult stage. Consequently, DU exposure during brain development caused modification in neuro-genesis processes associated to cognitive and emotional disorders at adult age. U could present a threat to human health, especially in pregnant women and children. (author)

  3. Potential Vorticity Streamers as Precursors to Tropical Cyclone Genesis in the Western Pacific

    Science.gov (United States)

    2012-03-01

    study a developing system with an extratropical precursor (TCS-037) developing into Tropical Storm 16W (TS 16W)” (Schönenberger 2010). This subsection...tropopause maps), the TC genesis event is termed a tropical transition (TT) case. If no such extratropical feature 38 is present, the storm in... extratropical origin is deemed to play an important role in the dynamical evolution leading to tropical cyclogenesis. In contrast, non-TT storms

  4. 76 FR 21403 - Notice of Availability of the Final Environmental Impact Statement for the Genesis Project...

    Science.gov (United States)

    2011-04-15

    ...: (1) The cumulative impacts of mining and related actions on affected resources, for example water... DEPARTMENT OF THE INTERIOR Bureau of Land Management [LLNV010000.L19900000.EX0000 241A; 11-08807... the Genesis Project, Eureka County, NV AGENCY: Bureau of Land Management, Interior. ACTION: Notice of...

  5. Geochemical geochronology and genesis of granite from Coronel Murta, Northeast of Minas Gerais, Brazil

    International Nuclear Information System (INIS)

    Soares, A.C.P.; Siga Junior, O.

    1987-01-01

    Geological, petrographic, geochemical (including rare-earth elements) and geochronological data of the Coronel Murta (Northeast Minas Gerais State) post-tectonic intrusive alkalic granites were summarized in order to discuss their genesis. This paper shows that Coronel Murta granites were generated by anatexis of dominantly metasedimentary rocks, in an ensialic environment, as the late results of an intraplate A-type subduction during the Brazilian Cycle. (author) [pt

  6. A 15N-poor isotopic composition for the solar system as shown by Genesis solar wind samples.

    Science.gov (United States)

    Marty, B; Chaussidon, M; Wiens, R C; Jurewicz, A J G; Burnett, D S

    2011-06-24

    The Genesis mission sampled solar wind ions to document the elemental and isotopic compositions of the Sun and, by inference, of the protosolar nebula. Nitrogen was a key target element because the extent and origin of its isotopic variations in solar system materials remain unknown. Isotopic analysis of a Genesis Solar Wind Concentrator target material shows that implanted solar wind nitrogen has a (15)N/(14)N ratio of 2.18 ± 0.02 × 10(-3) (that is, ≈40% poorer in (15)N relative to terrestrial atmosphere). The (15)N/(14)N ratio of the protosolar nebula was 2.27 ± 0.03 × 10(-3), which is the lowest (15)N/(14)N ratio known for solar system objects. This result demonstrates the extreme nitrogen isotopic heterogeneity of the nascent solar system and accounts for the (15)N-depleted components observed in solar system reservoirs.

  7. The Old English Genesis and Milton's Paradise Lost: the characterisation of Satan

    OpenAIRE

    Ramazzina, Elisa

    2016-01-01

    The aim of this study is to determine whether and to what extent the English poet John Milton may have been influenced in the composition of Paradise Lost by the Old English poem known as Genesis B. The paper will examine similarities and dif-ferences in the characterisation of Satan and of the temptation of Adam and Eve in both poems. The comparison between two of the illuminations of the Junius 11 ms. and the corresponding passages in Paradise Lost will be part of the analysis.

  8. Evaluation of clinical efficacy of a combined analgetic drug "Fanigan" for symptomatic treatment of patients with pain syndrome of various genesis

    Directory of Open Access Journals (Sweden)

    Mamchur V.Y.

    2017-04-01

    Full Text Available The authors studied the efficacy of combined drug Fanigan (paracetamol 500 mg and diclofenac sodium 50 mg (production of "Kusum Pharm" (Ukraine or "Kusum Heltker PVT. LTD" (India in tablets for symptomatic treatment of patients with pain syndrome. A pronounced clinical efficiency of its application in patients with pain syndrome of various genesis in a daily dose from 2 to 3 tablets for 3 to 7 days was established. The obtained data on the clinical efficacy of the drug. Fanigan in the treatment of patients with pain syndrome of various genesis allow to recommend it for application in wide clinical practice.

  9. A theory of the genesis of breast duct papilloma.

    Science.gov (United States)

    WHANG, J

    1960-03-01

    While it is not the intent to argue that papilloma never develops in the conventionally accepted manner (proliferative growth from the wall of a pre-existing cavity) a new, perhaps alternative, genesis is suggested. The concept is that, beginning with the usual lobular structure of the breast, first by hyperplasia and then by coalescence of alveoli, seen earliest at the periphery of the lobule, spaces appear between the content of the lobule and the wall. By confluence of these spaces a larger cystic cavity is formed. Coalescence of alveoli through the body of the central mass, in the same way as at the periphery, develops the familiar pattern of "papilloma." Following the earlier hyperplasia, regressive changes appear and may go on to complete disintegration of the papillary mass, leaving a smooth-walled cavity.

  10. Development of Chemical and Mechanical Cleaning Procedures for Genesis Solar Wind Samples

    Science.gov (United States)

    Schmeling, M.; Jurewicz, A. J. G.; Gonzalez, C.; Allums, K. K.; Allton, J. H.

    2018-01-01

    The Genesis mission was the only mission returning pristine solar material to Earth since the Apollo program. Unfortunately, the return of the spacecraft on September 8, 2004 resulted in a crash landing shattering the solar wind collectors into smaller fragments and exposing them to desert soil and other debris. Thorough surface cleaning is required for almost all fragments to allow for subsequent analysis of solar wind material embedded within. However, each collector fragment calls for an individual cleaning approach, as contamination not only varies by collector material but also by sample itself.

  11. On the genesis of spatio-temporal self-organized structures in plasma devices

    International Nuclear Information System (INIS)

    Talasman, S.J.; Sanduloviciu, M.

    1995-01-01

    The genesis of luminous sharply defined nearly spherical space charges structures formed in an Argon plasma column was experimental investigated. The results reveal spatio-temporal characteristics proper to systems resulting after a self-organization process. Their phenomenology involves electrical charges separation produced by symmetry breaking and spatial separation of the excitation and ionization cross sections functions in a region where electrons are accelerated and, as a result, the appearance of electrostatic forces that, acting as long range correlations, assures, together with dissipative effects, its stability. (Author) 8 Figs., 31 Refs

  12. Genesis 2 en 3 in 1 Timoteus 2: ’n motivering vir gedrag in die erediens, die gewone lewe of die huwelik?

    Directory of Open Access Journals (Sweden)

    Douw G. Breed

    2006-07-01

    Full Text Available Genesis 2 and 3 in 1 Timothy 2: a rationale for conduct in public worship, ordinary life, or marriage? In his exegesis of 1 Timothy 2:1-12, Breed (2006:247-261 shows that Paul does not give any indications in this text itself of whether the instructions in verses 8-12 were aimed at regulating conduct during public worship, in ordinary life or marriage. Paul supports the instructions he gives in 1 Timothy 2:11-12 in verses 13-15 by referring to Genesis 2 and 3. This article investigates whether there is any indication in Paul’s rationale of the context in which these instructions should be read. The study focuses on Paul’s reference to the order of creation (v. 13, Eve’s temptation (v. 14a, the state of transgression in which woman finds herself and her salvation by giving birth (v. 14b-15. This study concludes that in his references to Genesis 2 and 3, Paul does not give any indications of whether this instructions in 1 Timothy 2:8-15 deals with instructions for public worship, ordinary life or marriage.

  13. Magma genesis and slab-wedge interaction across an island arc-continent collision zone, East Sunda Arc, Indonesia

    NARCIS (Netherlands)

    Hoogewerff, J.A.

    1999-01-01

    This thesis presents the results of a detailed trace element and isotope geochemistry study into the magma-genesis ofvolcanoes in the Adonara-Pantar Section (APS) ofthe East Sunda Arc in Indonesia, a setting where an oceanic island arc is colliding with a passive continental margin. Sr, Nd, Pb, Ra,

  14. Magma genesis and slab-wedge interaction across an island arc-continent collision zone, East Sunda Arc, Indonesia

    NARCIS (Netherlands)

    Hoogewerff, J.A.

    1999-01-01

    This thesis presents the results of a detailed trace element and isotope geochemistry study into the magma-genesis ofvolcanoes in the Adonara-Pantar Section (APS) ofthe East Sunda Arc in Indonesia, a setting where an oceanic island arc is colliding with a passive continental margin. Sr, Nd, Pb,

  15. Some aspects of the genesis of heavy mineral assemblages in Lower Proterozoic uranium-gold conglomerates

    International Nuclear Information System (INIS)

    Clemmey, H.

    1982-01-01

    Some genetic models for Lower Proterozoic gold- and uranium-bearing pyritic conglomerates favour a modified placer origin in which low levels of atmospheric oxygen are used to account for the survival of uraninite and pyrite. There are many difficulties with such models. New evidence concerning the genesis of the deposits is derived from a clast of ferric iron clay thought to represent a precursor sediment of the Witwatersrand Basin. Reworking of such clays and transport of a magnetite and ferric clay assemblage with subsequent sulphidation, could account for the porous pyrites, the absence of magnetite and the lack of hydraulic equivalence of the mineral grains in the conglomerates. The presence of oxygen, as indicated by the ferric iron clasts, would account for the evidence of mobility of uranium and of gold and would enhance their extraction from source rocks; particularly the release of gold from a precursor auriferous iron formation source. It is suggested that some aspects of the genesis of uranium deposits of the Witwatersrand and Elliott Lake may be similar to those of the Phanerozoic 'Roll Front' ores involving interaction between oxidizing uraniferous groundwaters and previously sulphidized and reduzate facies sediments. (author)

  16. Microstructure and geochemical evidences for genesis of the Gol-Gohar iron deposit

    Directory of Open Access Journals (Sweden)

    Shahryar Mahmoudi

    2017-11-01

    Full Text Available Introduction The Gol-Gohar iron ore deposit located in 55 km South West of the city of Sirjan, in the Sanandaj-Sirjan structural zone. Sanandaj-Sirjan zone (SSZ is part of the Alpian-Hymalian orogenic belt and it is located in the west of the central Iran microplate. SSZ represented the metamorphic belt of the Zagros orogeny, that extends for 1500 km from Sirjan in the southeast to Sanandaj in the northwest of Iran (Mohajjel et al, 2003. The Gol-Gohar iron ore deposit is surrounded by a complex of igneous and metamorphic rocks mainly consisting of pelitic schists, basic schists, gneiss, amphibolite, marble, granodiorit, granite and mylonitic granite. In the early studies on the genesis of Gol-Gohr iron deposits, it was considered that sedimentary and tectonic processes were more effective in iron ore deposition. Later studies mainly confirmed a magmatic genesis for Gol-Gohar iron ore (Mucke and Golestaneh, 1982. Although some researchers argued that skarnisation process was the main cause of mineralisation (Hallaj and Jacobpor, 1991؛ Torabian, 2007, still some discussions on Gol-Gohr genesis are underway. Materials and methods – Gol-Gohar mine is divided into three blocks and several exploratory boreholes have been drilled down to 200 to 1400m depths in the third block. The representative samples were taken from exploration drill holes and outcrops around the mine. Microscopic observation (Zeiss Aksioscope in thin and polish sections show that the main ore mineral in the Gol-Gohar deposit is magnetite formed into two types with distinctive optical properties; the milky-gray magnetite (type1 named also “upper ore” and blue to brown magnetite (type2 named also “lower ore” (Mucke and Golestaneh, 1982. Mineralogy and microtectonic study were carried out on 100 thin and 30 polished sections using Zeiss research microscope. For geochemical analyses 20 samples were selected from 3 major exploration drill holes. After whole rock chemical

  17. Research on petrologic, geochemical characteristics and genesis of volcanic rocks in Dachangsha basin

    International Nuclear Information System (INIS)

    Wei Sanyuan

    1999-01-01

    On the basis of research on petrologic, geochemical characteristics and isotope composition of volcanic rocks in Dachangsha basin, the author concludes that the volcanic rocks formed from magma of different genesis and depth are double-cycle effusive. It is proposed that the magma forming the intermediate-basic volcanics of the first cycle comes from the mixing of the partial melting of the deep crust and mantle, and the intermediate-acidic volcanics of the secondary cycle are derived from the remelting of the upper crust

  18. [Spatial organization of bioelectrical brain activity in epilepsy and amenorrhea of central genesis].

    Science.gov (United States)

    Avakian, G N; Oleĭnikova, O M; Nerobkova, L N; Dovletkhanova, E R; Mitrofanov, A A; Gusev, E I

    2002-01-01

    The study aimed at modification of co-herent analysis (CA), as a mathematical method for EEG data processing for objective evaluation of bioelectric brain activity spatial organization in women with epilepsy and secondary amenorrhea of central genesis. One hundred sixty one women (30 with epilepsy, 116 with amenorrhea and 115 controls aged 15 to 41 years) have been examined. Characteristic changes of cortico-cortical inter- and intra-hemisphere relations for patients with catamenial (CTM) and noncatamenial (NCTM) epilepsy in different menstrual cycle terms were found. The most distinct changes were detected in theta-activity analysis. In the beginning of menstrual cycle, the patients with CTM epilepsy exhibited higher CA indices in theta-rhythm range in all right hemisphere pairs studied. On the contrary, patients with NCTM epilepsy exhibited lower CA indices mainly in the right brain hemisphere. alpha-rhythm spatial organization analysis in the same patients showed similar correlations, but they were better expressed in alpha-rhythm generation zone: in the beginning of menstrual cycle CA indices were high in patients with CTM epilepsy and low in those with NCTM epilepsy. Comparing to controls, patients with secondary amenorrhea of central genesis showed most distinct changes in theta-activity towards the CA indices increase in the majority of the leads. In patients with epilepsy and amenorrhea, CA indices of right brain hemisphere and intra-central temporal lead pairs were lower than in patients with amenorrhea without epilepsy by both alpha- and theta-rhythms.

  19. Elemental Redistribution at the Onset of Soil Genesis from Basalt as Measured in a Soil Lysimeter System

    Science.gov (United States)

    Wang, Y.; Umanzor, M.; Alves Meira Neto, A.; Sengupta, A.; Amistadi, M. K.; Root, R.; Troch, P.; Chorover, J.

    2017-12-01

    Elemental translocation, resulting in enrichment or depletion relative to parent rock, is a consequence of mineral dissolution and precipitation reactions of soil genesis. Accurate measurement of translocation in natural systems is complicated by factors such as parent material heterogeneity and dust deposition. In the present work, a fully controlled and monitored 10° sloping soil lysimeter with known homogeneous initial conditions, was utilized to investigate initial stages of soil genesis from 1 m3 of crushed basalt. Throughout the two-year experiment, periodic irrigation coupled with sensor measurements enabled monitoring of changes in internal moisture states. A total 15-meter water influx resulted in distinct efflux patterns, wetting and drying cycles, as well as high volume water storage. Biological changes, such as algal and grass emergence, were visible on the soil surface, and microbial colonization throughout the profile was measured in a companion study, suggesting that biogeochemical hotspots may have formed. Forensic excavation and sampling of 324 voxels captured the final state heterogeneity of the lysimeter with respect to length and depth. Total elemental concentrations and a five-step sequential extraction (SE) scheme quantified elemental redistributions into operationally-defined pools including exchangeable, poorly-crystalline (hydr)oxides, and crystalline (hydr)oxides. Data were correlated to water flux and storage that was determined from sensor and tracer data over the two years of rock-water interaction; then used to map 2D cross-sections and identify geochemical hotspots. Total and SE Fe concentrations were used to establish a governing mass balance equation, and sub mass balance equations with unique partitioning coefficients of Fe were developed for each SE pool, respectively. The results help to explain elemental (e.g., Fe) lability and redistribution due to physical and geochemical weathering during the initial stages of soil genesis.

  20. 75 FR 52966 - Notice of Availability of the Final Environmental Impact Statement for the Genesis Solar, LLC...

    Science.gov (United States)

    2010-08-30

    ... following Web site: http://www.blm.gov/ca/st/en/fo/palmsprings/Solar_Projects/Genesis_Ford_Dry_Lake.html.... Construction and operation of the Proposed Action would disturb a total of about 1,800 acres within the site... facilities for storm water flow and discharge. 6. Temporary construction laydown area(s) within the larger...

  1. The Old English Genesis and Milton’s Paradise Lost: the characterisation of Satan

    Directory of Open Access Journals (Sweden)

    Elisa Ramazzina

    2016-07-01

    Full Text Available The aim of this study is to determine whether and to what extent the English poet John Milton may have been influenced in the composition of Paradise Lost by the Old English poem known as Genesis B. The paper will examine similarities and dif-ferences in the characterisation of Satan and of the temptation of Adam and Eve in both poems. The comparison between two of the illuminations of the Junius 11 ms. and the corresponding passages in Paradise Lost will be part of the analysis.

  2. Genesis nature of financial strategy

    Directory of Open Access Journals (Sweden)

    O.V. Pashchenko

    2015-03-01

    Full Text Available The article is devoted to the study of the origin and history of the interpretation of the genesis of «strategy», «financial strategy», its elements and composite types. Scientists studied different views on the concept of strategy. Several specific positions founders of different approaches to define the strategy of schools operating strategies involved in the formulation and implementation of the concept of «strategy». Evaluation of different schools of strategies that deepened understanding of the industry and its strategy in the early stages of formation. Based on the works of various scholars studied by the author actually proposed interpretation of the concept strategy. The general industry and functional strategies which include the following strategies: innovation, resource, financial, production, marketing and human resources. Allocated financial strategy and its significant impact on other strategies. Author developed financial sector strategy and financial strategy of competitive enterprise. The importance of financial strategies under conditions of companies and the industry as a whole, as well as components of development of financial strategy. Deals with the factors that must be considered in the development and implementation of financial strategies. The systems analysis strategies and the impact on financial results, the estimation of their attractiveness and risk. Considered classification on the basis of financial strategies and sectoral orientation of the financial sector strategy based on company size, its form and noted the importance of this trait in systematizing strategies. The expediency of the financial strategy. Defined competitive advantage and efficiency of business and industry through the implementation of various financial strategies.

  3. Variations in large-scale tropical cyclone genesis factors over the western North Pacific in the PMIP3 last millennium simulations

    Science.gov (United States)

    Yan, Qing; Wei, Ting; Zhang, Zhongshi

    2017-02-01

    Investigation of past tropical cyclone (TC) activity in the Western North Pacific (WNP) is potentially helpful to enable better understanding of future TC behaviors. In this study, we examine variations in large-scale environmental factors important to TC genesis in the last millennium simulations from the Paleoclimate Modelling Intercomparison Project Phase 3 (PMIP3). The results show that potential intensity, a theoretical prediction of the maximum TC intensity, is increased relative to the last millennium in the north part of the WNP in the Medieval Climate Anomaly (MCA; 950-1200 AD) while it is decreased in the Little Ice Age (LIA; 1600-1850 AD). Vertical wind shear that generally inhibits TC genesis is enhanced (reduced) to the south of 20°N and is reduced (enhanced) to the north in the MCA (LIA). Relative humidity (at 600 hPa) that measures the mid-tropospheric moisture content broadly shows an increase (decrease) in the MCA (LIA). A genesis potential index indicates that conditions are generally favorable (unfavorable) for TC formation in the WNP in the MCA (LIA), especially in the northern part. Taking changes in steering flows into account, there may be an increasing (decreasing) favorability for storm strikes in East Asia in the MCA (LIA). The estimated TC activity is consistent with the geological proxies in Japan, but contradicts with the typhoon records in southern China and Taiwan. This model-data discrepancy is attributed to the limitations in both simulations and reconstructions.

  4. Visual Representation in GENESIS as a tool for Physical Modeling, Sound Synthesis and Musical Composition

    OpenAIRE

    Villeneuve, Jérôme; Cadoz, Claude; Castagné, Nicolas

    2015-01-01

    The motivation of this paper is to highlight the importance of visual representations for artists when modeling and simulating mass-interaction physical networks in the context of sound synthesis and musical composition. GENESIS is a musician-oriented software environment for sound synthesis and musical composition. However, despite this orientation, a substantial amount of effort has been put into building a rich variety of tools based on static or dynamic visual representations of models an...

  5. REE geochemistry and genesis of Daxin uranium deposit

    International Nuclear Information System (INIS)

    Li Zhixing; Qi Fucheng; He Zhongbo; Zhang Zilong

    2011-01-01

    Through the analysis on typical REE parameters,chondrite-normalized REE patterns and hierarchical cluster analysis of rocks in the structural-geochemical zonation in Daxin uranium deposit, the paper discusses the uranium source and genesis. The study shows that the uranium source mainly came from Cambrian System. The Devonian System is maily as the favorable room for saving ores in addition to pre-concentrated room for uranium. Underground water resulted from early and late Yanshanian movement and the heating of volcanic rock was turned into geothermal water and it was moved upward by the force of tectonic movement. The geothermal water mainly extracted active uranium from the Cambrian rocks, then moved upward along main regional fault (F2) connecting the Cambrian rocks and the Devonian rocks until it arrived in structural fracture zone which was controlled by secondary faults (F13, F23, F33). At last, the uranium element in geothermal water was precipitated and concentrated into the uranium deposit in reducing environment of enriched organic material and pyrite. (authors)

  6. The genesis of WiFi and its applications

    CERN Multimedia

    CERN. Geneva

    2008-01-01

    In 1985 changes to US regulations caused a paradigm shift by permitting the use of radio spectrum for devices that did not need to have an end-user license. After a few years, products appeared on the market and a group developed a standard for broadband wireless communications among computers. The presentation will explain how the standard developed and was adopted by the Wi-Fi Alliance, as well as the global harmonization and expansion of the available radio spectrum to over half a GHz. The success of Wi-Fi and user innovation and initiatives makes it a vehicle to bring broadband internet to rural areas both in developing as well as in developed countries. Vic Hayes is a Senior Research Fellow at the Delft University of Technology and is writing a book titled "The genesis of Wi-Fi and the road toward global success". He holds a BSEE and joined NCR in the Netherlands in 1974. He co-established and chaired the IEEE 802.11 Standards Working Group for Wireless Local Area Networks and became known as the "Fathe...

  7. Seismo-tectonic model regarding the genesis and occurrence of Vrancea (Romania) earthquakes

    International Nuclear Information System (INIS)

    Enescu, D.; Enescu, B.D.

    1998-01-01

    The first part of this paper contains a very short description of some previous attempts in seismo-tectonic modeling of Vrancea zone. The seismo-tectonic model developed by the authors of this work is presented in the second part of the paper. This model is based on the spatial distribution of hypo-centers and focal mechanism characteristics. Lithosphere structure and tectonics of the directly implied zones represent very important characteristics of the seismo-tectonic model. Some two-dimensional and three-dimensional sketches of the model, which satisfy all the above mentioned characteristics and give realistic explanations regarding the genesis and occurrence of Vrancea earthquakes are presented. (authors)

  8. Recent Optical and SEM Characterization of Genesis Solar Wind Concentrator Diamond on Silicon Collector

    Science.gov (United States)

    Allton, Judith H.; Rodriquez, M. C.; Burkett, P. J.; Ross, D. K.; Gonzalez, C. P.; McNamara, K. M.

    2013-01-01

    One of the 4 Genesis solar wind concentrator collectors was a silicon substrate coated with diamond-like carbon (DLC) in which to capture solar wind. This material was designed for analysis of solar nitrogen and noble gases [1, 2]. This particular collector fractured during landing, but about 80% of the surface was recovered, including a large piece which was subdivided in 2012 [3, 4, 5]. The optical and SEM imaging and analysis described below supports the subdivision and allocation of the diamond-on-silicon (DOS) concentrator collector.

  9. Characteristics and genesis of porphyroclastic lava rock in Xiangshan

    International Nuclear Information System (INIS)

    Zhou Xiaohua; Wang Zhuning

    2012-01-01

    Due to the transitional characteristics of porphyroclastic lava rock in Xiangshan of Jiangxi province, there are a variety of views on its genesis, petrographic attribution. This is because the marginal facies of the porphyroclastic lava is with ignimbrite and tuff characteristics, its transition phase has the characteristics of lava, and its intermediate phase has the feature of sub-volcanic rocks, further more, different texture of the rocks bears transition relationship. By the study of mineral composition, REE pattern, trace elements, isotopes, we put forward that the porphyroclastic lava is formed by the remelting of basement metamorphic rocks. The rocks was believed to be formed in the environment similar to volcanics and subvolcanics, and quite different to plutonic rocks due to the features of low-structure of potassium feldspar phenocrysts and solution mechanism, because the porphyroclastic lava phenocrysts occurs as fragments and maybe related to cryptoexplosion. Therefore the rocks was believed to belong to the volcano extrusive facies. (authors)

  10. The genesis of victimization surveys and of the realist-constructionist divide.

    Science.gov (United States)

    de Castelbajac, Matthieu

    2017-09-01

    The invention of victimization surveys is often presented as a synthesis of the two theoretical attitudes that, supposedly, dominated the 1960s debate over official crime statistics: realism and social constructionism. This paper turns this genesis story on its head. Using original archives, I argue that victimization surveys responded to organizational opportunities in the field of applied research. It was only after the fact that two of their architects seized the debate on crime measurement to broadcast their invention. In so doing they strategically recast the terms of this debate into a binary division between two antithetical social ontologies. This case is used to discuss how social scientists come to reinterpret and misunderstand their history. © 2017 Wiley Periodicals, Inc.

  11. Glucose-regulated protein 78 regulates the expression of mitochondrial genesis proteins in HBV-related hepatocellular carcinoma: a clinical analysis

    Directory of Open Access Journals (Sweden)

    LI Yaping

    2017-10-01

    Full Text Available ObjectiveTo investigate the expression of glucose-regulated protein 78 (GRP78 in HBV-related hepatocellular carcinoma (HBV-HCC and its association with clinicopathological features, as well as its regulatory effect on mitochondrial genesis proteins in hepatoma cells, and to provide a basis for new strategies for the prevention and treatment of HCC. MethodsTissue samples were collected from 54 patients with HBV-HCC, and immunohistochemistry and Western blot were used to measure the expression of GRP78, Lon, TFAM, and cytochrome C oxidase Ⅳ (COXⅣ. The expression of GRP78 in hepatoma cells was interfered by siRNA, and then the expression of GRP78, Lon, mitochondrial transcription factor A (TFAM, and COX Ⅳ was measured. Quantitative real-time PCR was used to measure the level of mitochondrial DNA (mtDNA in clinical specimens and HCC cells after GRP78 expression was interfered with. A statistical analysis was performed for clinical and experimental data. The t-test was used for comparison of continuous data between groups, the Fisher′s exact test was used for comparison of categorical data between groups, and the Kaplan-Meier method was used for survival analysis. Results Compared with the adjacent tissues, HBV-HCC tissues had significantly higher expression of GRP78 and Lon (t=9.135 and 5523, both P<0.0001 and significantly lower expression of the mitochondrial genesis proteins TFAM and COX Ⅳ and mtDNA level (t=2.765, 4260, and 12.280, P=0.011, <0.001, and <0.001. There were significant increases in the expression of the mitochondrial genesis proteins TFAM and COX Ⅳ and mtDNA level after the interference with GRP78 expression in hepatoma cells (all P<0.05. There were significant differences in the expression of GRP78 between patients with different numbers of tumors, patients with and without portal vein tumor thrombus, and patients with different tumor stages (P=0.016, 0.003, and 0.045. The patients with low GRP78

  12. Vrou as beeld van God, Deel 1: 'n Historiese ondersoek - Vanaf Genesis tot die Middeleeue

    Directory of Open Access Journals (Sweden)

    Yolanda Dreyer

    2000-12-01

    Full Text Available Woman created in the image of God, Part 1: a historical investigation - from Genesis to the Middle Ages. This study indicates that the traditions in the Pentateuch, especially the creation traditions, implied the egalitarian status of man and woman as image of God. The context of this traditions, however, was patriarchal and thus opened the possibility of the exploitation of women. Though Genesis 1:27 does not specifically attest to the asymmetry between man and woman in patriarchal society, the fate of women in general was bound up with the presentation of God as a male creator. The implications of this presentation can be clearly seen in texts of the intertestamental period. The study points out the degree to which Philo's view of a hierarchy concerning man and woman as immanent to God's order of creation, strongly influenced Christian thought on the place of women. Since the "fall of woman" necessitates a "soteriology", women in general are portrayed negatively in patristic texts. Mary is seen as the positive counterpart of Eve. The image of women then becomes that of submission on account of their alienation from God. The article concludes with the view of Thomas Aquinas that the subservience of slaves is less than that of women, because in their case it is not an order of creation.

  13. Genesis Solar Wind Collector Cleaning Assessment: Update on 60336 Sample Case Study

    Science.gov (United States)

    Goreva, Y. S.; Allums, K. K.; Gonzalez, C. P.; Jurewicz, A. J.; Burnett, D. S.; Allton, J. H.; Kuhlman, K. R.; Woolum, D.

    2015-01-01

    To maximize the scientific return of Genesis Solar Wind return mission it is necessary to characterize and remove a crash-derived particle and thin film surface contamination. A small subset of Genesis mission collector fragments are being subjected to extensive study via various techniques. Here we present an update on the sample 60336, a Czochralski silicon (Si-CZ) based wafer from the bulk array (B/C). This sample has undergone multiple cleaning steps (see the table below): UPW spin wash, aggressive chemical cleanings (including aqua regia, hot xylene and RCA1), as well as optical and chemical (EDS, ToF-SIMS) imaging. Contamination appeared on the surface of 60336 after the initial 2007 UPW cleaning. Aqua regia and hot xylene treatment (8/13/2013) did little to remove contaminants. The sample was UPW cleaned for the third time and imaged (9/16/13). The UPW removed the dark stains that were visible on the sample. However, some features, like "the Flounder" (a large, 100 micron feature in Fig. 1b) appeared largely intact, resisting all previous cleaning efforts. These features were likely from mobilized adhesive, derived from the Post-It notes used to stabilize samples for transport from Utah after the hard landing. To remove this contamination, an RCA step 1 organic cleaning (RCA1) was employed. Although we are still uncertain on the nature of the Flounder and why it is resistant to UPW and aqua regia/hot xylene treatment, we have found RCA1 to be suitable for its removal. It is likely that the glue from sticky pads used during collector recovery may have been a source for resistant organic contamination [9]; however [8] shows that UPW reaction with crash-derived organic contamination does not make particle removal more difficult.

  14. Genesis of the concept "mergers and acquisitions" in the world scientific knowledge

    Directory of Open Access Journals (Sweden)

    T. V. Reshetnikova

    2017-09-01

    Full Text Available The authors examine the genesis of the concepts of "merger" and "acquisition" in terms of their essence, the need for implementation in the modern economy, the role in the restructuring of the company or business as a whole, the forms of manifestation in the market of corporate control. The authors compare the classical approaches to the examination of essential characteristics in the foreign economic literature with those available in Russian economic literature and used in Russian practice. Both foreign and Russian literature have two clearly distinguished, fundamentally different positions of scientists on the considered definition. Herewith, the first group of researchers separates the terms "merger" and "acquisition", understanding by merging such a transaction between companies in which only one of the involved parties survives, usually the initiator of the transaction. The rest of the companies leave the markets (financial and commodity. This researches consider acquisition as such a process, after which the absorbed company continues to be present in the markets as a subsidiary of the company initiating the transaction. The authors justify new challenges in the M&A market, and reveal the reasons for their appearance. The article presents the genesis of the concepts of mergers and acquisitions from the point of view of their classification by essential characteristics, and reveals common features that practically all foreign and Russian researchers in this field of knowledge identify. The article also shows the distinctive features noted by scientists that expand the possibilities for business restructuring taking into account the processes of corporate control market. The authors study the classification of mergers and acquisitions with the substantiation own position on the sufficiency/insufficiency of the criterion for classifying the studied concepts to different groups; substantiate appearance of definition "transboundary mergers and

  15. The genesis solar-wind sample return mission

    International Nuclear Information System (INIS)

    Wiens, Roger C.

    2009-01-01

    different solar isotopic composition and each invoking a different early solar-system process to produce the heterogeneity. Other volatiles such as C, N, and H may also have experienced similar effects, but with only two isotopes it is often impossible to distinguish with these elements between mass-dependent fractionation and other effects such as mixing or mass-independent fractionation. Table 1 provides a summary of the major measurement objectives of the Genesis mission. Determining the solar oxygen isotopic composition is at the top of the list. Volatile element and isotope ratios constitute six of the top seven priorities. A number of disciplines stand to gain from information from the Genesis mission, as will be discussed later. Based on the Apollo solar-wind foil experiment, the Genesis mission was designed to capture solar wind over orders of magnitude longer duration and in a potentially much cleaner environment than the lunar surface.

  16. Electron microscope study of the genesis of strain-induced martensite embryos

    International Nuclear Information System (INIS)

    Staudhammer, K.P.; Hecker, S.S.; Murr, L.E.

    1984-01-01

    Previous work of Olson and Cohen and Murr, et al., is used to describe the genesis of martensite embryos which form at the intersection of microscopic shear bands in deformed type 304 stainless steel. It is shown that the intersection volume included within intersecting shear bands contains irregular and smaller dispersed volume segments forming α' martensite (bcc). These correspond to the satisfaction of specific intersections of stacking faults or partial dislocations on approximately every second (111)/sub fcc/ plane in one direction, and every third (111)/sub fcc/ plane in the other (conjugate) direction. The requisite stacking fault or partial dislocation arrangements are produced in an irregular fashion resulting in α' martensite embryos nucleating in an incomplete and irregular fashion within the intersection volume. 9 references, 2 figures

  17. Influence of Different Patellofemoral Design Variations Based on Genesis II Total Knee Endoprosthesis on Patellofemoral Pressure and Kinematics.

    Science.gov (United States)

    Leichtle, Ulf G; Lange, Barbara; Herzog, Yvonne; Schnauffer, Peter; Leichtle, Carmen I; Wülker, Nikolaus; Lorenz, Andrea

    2017-01-01

    In total knee arthroplasty (TKA), patellofemoral groove design varies greatly and likely has a distinct influence on patellofemoral biomechanics. To analyse the selective influence, five patellofemoral design variations were developed based on Genesis II total knee endoprosthesis (original design, being completely flat, being laterally elevated, being medially elevated, and both sides elevated) and made from polyamide using rapid prototyping. Muscle-loaded knee flexion was simulated on 10 human knee specimens using a custom-made knee simulator, measuring the patellofemoral pressure distribution and tibiofemoral and patellofemoral kinematics. The measurements were carried out in the native knee as well as after TKA with the 5 design prototypes. The overall influence of the different designs on the patellofemoral kinematics was small, but we found detectable effects for mediolateral tilt ( p patellofemoral pressures, major interindividual differences were seen between the designs, which, on average, largely cancelled each other out. These results suggest that the elevation of the lateral margin of the patellofemoral groove is essential for providing mediolateral guidance, but smooth contouring as with original Genesis II design seems to be sufficient. The pronounced interindividual differences identify a need for more patellofemoral design options in TKA.

  18. Genesis of natural cokes: Some Indian examples

    Energy Technology Data Exchange (ETDEWEB)

    Singh, Ashok K.; Sharma, Mamta [Central Institute of Mining and Fuel Research, Dhanbad, PIN-828108 (India); Singh, Mahendra P. [Banaras Hindu University, Varanasi, PIN-221005 (India)

    2008-06-13

    In Indian coalfields huge amounts of natural coke have been produced due to magmatic intrusions. Jharia Coalfield in eastern part of India alone contains approximately 2000 Mt of baked coking coal as a consequence of these intrusions in the form of discordant and concordant bodies. This paper is an effort to investigate the effect of carbonization in two intrusion affected coal seams of Ena (seam XIII) and Alkusa (seam XIV) collieries of Jharia Coalfield. Natural coke is derived from coking coal under in-situ conditions due to intense magmatic induced heat and overburden pressure. Natural coke is characterized by the presence of low volatile matter and high ash contents and organic constituents showing isotropy and anisotropy. Through physical, petrographic and chemical properties of natural coke or 'jhama' as determined by various methods it has been established that the reactives in the unaltered coals (vitrinite, liptinite, pseudovitrinite, reactive semifusinite, etc.) are < 25.0 vol.%, moisture < 2.5%, volatile matter < 15.0% and hydrogen < 4.0%. The temperatures attained in the coal seams have been deciphered using some standard models, which indicate that a temperature {proportional_to} 1000 C was attained. This produced huge amount of anisotropic and deposited carbons. An attempt has been made to understand the factors that influence the genesis of natural coke and heat altered maceral products in coals in Indian coalfields. (author)

  19. GENESIS - The GENEric SImulation System for Modelling State Transitions.

    Science.gov (United States)

    Gillman, Matthew S

    2017-09-20

    This software implements a discrete time Markov chain model, used to model transitions between states when the transition probabilities are known a priori . It is highly configurable; the user supplies two text files, a "state transition table" and a "config file", to the Perl script genesis.pl. Given the content of these files, the script generates a set of C++ classes based on the State design pattern, and a main program, which can then be compiled and run. The C++ code generated is based on the specification in the text files. Both multiple branching and bi-directional transitions are allowed. The software has been used to model the natural histories of colorectal cancer in Mexico. Although written primarily to model such disease processes, it can be used in any process which depends on discrete states with known transition probabilities between those states. One suitable area may be in environmental modelling. A test suite is supplied with the distribution. Due to its high degree of configurability and flexibility, this software has good re-use potential. It is stored on the Figshare repository.

  20. [Autism and epigenetics. A model of explanation for the understanding of the genesis in autism spectrum disorders].

    Science.gov (United States)

    Arberas, Claudia; Ruggieri, Víctor

    2013-01-01

    Autism spectrum disorders are characterized by impairment of social integration and language development and restricted interests. Autism spectrum disorders manifest during childhood and may have a varying clinical expression over the years related to different therapeutic approaches, behavior-modifying drugs, and environmental factors, among others. So far, the genetic alterations identified are not sufficient to explain the genesis of all these processes, as many of the mutations found are also present in unaffected individuals. Findings on the underlying biological and pathophysiological mechanisms of entities strongly associated with autism spectrum disorders, such as Rett, fragile X, Angelman, and fetal alcohol syndromes, point to the role of epigenetic changes in disorders of neurodevelopment. Epigenetic phenomena are normal biological processes necessary for cell and thus human life, especially related to embryonic development. Different phenomena that affect epigenetic processes (changes that change operation or expression of a gene, without modifying the DNA structure) have also been shown to be important in the genesis of neurodevelopmental disorders. Alterations in the epigenetic mechanism may be reversible, which may explain the variation in the autism phenotype over time. Here we analyze the normal epigenetic mechanisms, autism spectrum disorders, their association with specific entities associated with altered epigenetic mechanisms, and possible therapeutic approaches targeting these alterations.

  1. The genesis of the Brazilian nation in XIX century’s iconography

    Directory of Open Access Journals (Sweden)

    Verediana C. da Silva

    2013-06-01

    Full Text Available This research aims to understand the genesis of the idea of Brazilian nation through the nineteenth century’s iconography, approaching the study of images and deepening into the analysis of four artworks: Engenho da cachoeira. Corte de cana-de-açúcar by Hércule Florence, Primeira Missa no Brasil by Victor Meirelles, O Grito do Ipiranga by Pedro Américo and Evangelho das Selvas by Benedito Calixto. Besides the pictures we paid attention to the texts belonging to the same period, mainly those produced by the cultural elite related to the Instituto Histórico e Geográfico Brasileiro (IHGB, to the travel reports as text-images, as well as to the emergence of the Instituto and of the Academia Imperial de Belas Artes (AIBA in a context of pursuit of homogeneity in the promising Brazilian nation.

  2. SOME CONSIDERATIONS CONCERNING THE ROLE OF COSMIC ENVIRONMENT IN SOIL GENESIS AND EVOLUTION

    Directory of Open Access Journals (Sweden)

    I. Munteanu

    2011-12-01

    Full Text Available The present day concept of soil is strongly connected to the terrestrial environment. Among the cosmic factors of soil genesis the energy (as light and heat provided by the Sun is by far the most important. The other outer space possible agents e.g. meteorites, comets, cosmic radiation and cosmic dust, are usually neglected or scarcely mentioned. The advancing of cosmic exploration spurred soil scientists to extend their interest upon the extraterrestrial regoliths of Earth-like planets (Mars, Venus and Moon. The concept of “Universal soil” in whose genesis the biotic factor and water are not mandatory, has been recently advanced. The first papers about “lunar soils” are already quoted in soil science literature; some also speak about “Martian soil” or “Venusian soil”. Although these seem to be mere regoliths quite different from the “terrestrial soil” (by absence of life and water one believes that they may give information about impact upon lithological material of severe environment of these planets. This paper tries to outline the cosmic destiny of the soil, to enlarge its meaning and to reveal the hidden connections that the soil has with some planetary and cosmic parameters. In cosmic vision the “soil” – either “lunar”, “martian”, or “terrestrial” – can be viewed as the interface of energy and matter exchange between the land masses of these celestial body and their cosmic environment. The role of the solar activity, extragalactic events, distance from the Sun, obliquity (tilt of Earth’s rotation axis and Earth’s orbit circularity are analyzed in connection with Quaternary glaciations and their influences upon the development of terrestrial soils. The influence of Moon is emphasized as being very important in shaping the zonal geography of the terrestrial soils.

  3. Sun-genesis 21: Empowering the global village in the digital age and the solar century

    Energy Technology Data Exchange (ETDEWEB)

    Hamasaki, Les [Los Angeles, CA (United States)

    2000-07-01

    Sun-Genesis 21 is a global economic development plan for creating an environmentally sustainable future in the developing world. Its premise is that the solution to the survival of civil stability and democracy in developing countries in the Information Age is to slow the migration of the rural poor into the urban centers as well as dispersing some of the residents of the already impacted cities into new agro-communities. This strategy envisions empowering the 25 million coffee farmers located in the poorest countries in the world to control their own economic destiny by marketing their products directly to the international marketplace over the World Wide Web (Coffee Belt Plan 2020). The plan also envisions creating a network of new agricultural communities called World Farm Solar Telecommunities that utilizes telecommunications and environmental technologies to disperse the impacted urban population. Proven profitable commodities such as industrial hemp, aloe vera, and aquacultural farming will be the economic foundation of these agro-communities. The goal is to empower rural agro-entrepreneurs to become an economic engine for job creation and be able to afford the Coffee Solar Televillages that include distant learning centers, telemedicine clinics, food processing centers, e-commerce centers, and solar crop-drying centers. The Genesis 21 program includes creative financing strategies to deal with these massive problems of poverty and hunger through the concept of trade, not aid, including the use of barter in a proposed Green Technology for Green Coffee program. [Spanish] Sun-Genesis 21 es un plan global de desarrollo economico para crear un futuro ambiental sustentable en el mundo en desarrollo. La premisa del plan es que la solucion para la supervivencia de la estabilidad civil y la democracia en paises en desarrollo dentro de la Era de la Informacion es desacelerar la migracion de la gente pobre de las areas rurales hacia los centros urbanos, asi como

  4. GENESIS OF INTERPLANETARY INTERMITTENT TURBULENCE: A CASE STUDY OF ROPE–ROPE MAGNETIC RECONNECTION

    Energy Technology Data Exchange (ETDEWEB)

    Chian, Abraham C.-L.; Loew, Murray H. [Department of Biomedical Engineering, George Washington University, Washington, DC 20052 (United States); Feng, Heng Q. [Institute of Space Physics, Luoyang Normal University, Luoyang (China); Hu, Qiang [Department of Space Science and CSPAR, University of Alabama in Huntsville, Huntsville, AL 35805 (United States); Miranda, Rodrigo A. [UnB-Gama Campus, and Plasma Physics Laboratory, Institute of Physics, University of Brasília (UnB), Brasília DF 70910-900 (Brazil); Muñoz, Pablo R. [Department of Physics and Astronomy, University of La Serena, Av. Juan Cisternas 1200, La Serena (Chile); Sibeck, David G. [NASA Goddard Space Flight Center, Greenbelt, MD 20771 (United States); Wu, De J., E-mail: abraham.chian@gmail.com [Purple Mountain Observatory, Chinese Academy of Sciences, Nanjing 210008 (China)

    2016-12-01

    In a recent paper, the relation between current sheet, magnetic reconnection, and turbulence at the leading edge of an interplanetary coronal mass ejection was studied. We report here the observation of magnetic reconnection at the interface region of two interplanetary magnetic flux ropes. The front and rear boundary layers of three interplanetary magnetic flux ropes are identified, and the structures of magnetic flux ropes are reconstructed by the Grad–Shafranov method. A quantitative analysis of the reconnection condition and the degree of intermittency reveals that rope–rope magnetic reconnection is the most likely site for genesis of interplanetary intermittency turbulence in this event. The dynamic pressure pulse resulting from this reconnection triggers the onset of a geomagnetic storm.

  5. The genesis of period-adding bursting without bursting-chaos in the Chay model

    International Nuclear Information System (INIS)

    Yang Zhuoqin; Lu Qishao; Li Li

    2006-01-01

    According to the period-adding firing patterns without chaos observed in neuronal experiments, the genesis of the period-adding 'fold/homoclinic' bursting sequence without bursting-chaos is explored by numerical simulation, fast/slow dynamics and bifurcation analysis of limit cycle in the neuronal Chay model. It is found that each periodic bursting, from period-1 to 7, is separately generated by the corresponding periodic spiking pattern through two period-doubling bifurcations, except for the period-1 bursting occurring via a Hopf bifurcation. Consequently, it can be revealed that this period-adding bursting bifurcation without chaos has a compound bifurcation structure with transitions from spiking to bursting, which is closely related to period-doubling bifurcations of periodic spiking in essence

  6. Extraction of Solar Wind Nitrogen and Noble Gases From the Genesis Gold Foil Collector

    Science.gov (United States)

    Schlutter, D. J.; Pepin, R. O.

    2005-12-01

    The Genesis gold foil is a bulk solar wind collector, integrating fluences from all three of the wind regimes. Pyrolytic extraction of small foil samples at Minnesota yielded He fluences, corrected for backscatter, in good agreement with measurements by on-board spacecraft instruments, and He/Ne elemental ratios close to those implanted in collector foils deployed on the lunar surface during the Apollo missions. Isotopic distributions of He, Ne and Ar are under study. Pyrolysis to temperatures above the gold melting point generates nitrogen blanks large enough to obscure the solar-wind nitrogen component. An alternative technique for nitrogen and noble gas extraction, by room-temperature amalgamation of the gold foil surface, will be discussed. Ne and Ar releases in preliminary tests of this technique on small foil samples were close to 100% of the amounts expected from the high-temperature pyrolysis yields, indicating that amalgamation quantitatively liberates gases from several hundred angstroms deep in the gold, beyond the implantation depth of most of the solar wind. Present work is focused on two problems currently interfering with accurate nitrogen measurements at the required picogram to sub-picogram levels: a higher than expected blank likely due to tiny air bubbles rolled into the gold sheet during fabrication, and the presence of a refractory hydrocarbon film on Genesis collector surfaces (the "brown stain") that, if left in place on the foil, shields the underlying gold from mercury attack. We have found, however, that the film is efficiently removed within tens of seconds by oxygen plasma ashing. Potential nitrogen contaminants introduced during the crash of the sample return canister are inert in amalgamation, and so are not hazards to the measurements.

  7. Effect of X-ray contrast agents on hemostasis and its role in the genesis of adverse reactions

    International Nuclear Information System (INIS)

    Sviridov, N.K.; Napolov, Yu.K.

    2001-01-01

    Based on available data, the effect of X-ray contrast agents (XCA) on homeostasis and its role in side reactions genesis are discussed. It is shown that the contrast agent type used can essentially affect the thrombocytes. Nonionic XCA are able to increase the thrombocytes degranulation in case of coronarography and percutaneous transluminal coronary angioplastics with release of procoagulants in vessel gap. This effect can to lead to acute thromboses and be the start of restenosis [ru

  8. Molecular nuclear imaging of tumoral angio genesis using a rgd-containing tracer, Raft-RGD, targeted at the neo vessel-specific integrin αvβ3

    International Nuclear Information System (INIS)

    Sancey, L.

    2006-06-01

    Tumoral neo-angio genesis targeting is currently a major field of research for the diagnostic and treatment of solid tumors. Endothelial cells from neo vessels over express several specific markers such as the α v β 3 integrin, which binds RGD (-Arg-Gly-Asp-)- containing peptides. We evaluated the potential of a novel radiotracer - RAFT-RGD - for the molecular nuclear imaging of neo vessels. In vitro, the coupling of 4 c(RGDfK) to the RAFT platform resulted in an increased cellular uptake of the tracer by α v β 3 positive cells when compared to c(RGDfK). Furthermore, RAFTRGD has a higher affinity than c(RGDfK) and similar properties for angio genesis inhibition. In vivo, both α v β 3 positive and negative tumors were visible by non invasive whole body planar and tomographic imaging from 30 min to 24 h post-injection, using a gamma camera dedicated to small animal imaging. Despite a lack of significant contrast improvement compare with c(RGDfK), RAFT-RGD could represent a promising tracer for tumoral angio genesis since it could provide invaluable information about tumor development and treatment efficacy in Nuclear Medicine departments. Furthermore, thanks to its chemical structure, RAFT-RGD can be labelled with a variety of radioisotopes including γ and β - emitters, allowing interesting therapeutical applications such as internal targeted radiotherapy. (author)

  9. Organizational and technological genesis as a tool for strategic planning of large-scale real estate development projects

    Directory of Open Access Journals (Sweden)

    Gusakova Elena

    2018-01-01

    Full Text Available Conceptual planning and implementation of large-scale real estate development projects is one of the most difficult tasks in the organization of construction. In the Russian practice, a large experience of development, complex reorganization and redevelopment of large development areas is accumulated. The methodological basis for solving similar problems is the organizational and technological genesis, which considers the development of the project during the full life cycle. An analysis of this experience allows us to talk about the formation of new and effective approaches and methods within the organizational and technological genesis. Among them, the most significant and universal approaches should be highlighted: The concept of real estate development, which explains the reasons and objective needs for project transformations during its life cycle, as well as to increase the adaptive capabilities of design decisions and the project's suitability for the most likely future changes; Development project of joint action, which is based on the balance of interests of project participants; Master planning of the life cycle stages of the project and subprojects, based on the rethinking of the theory and methods of the construction organization, and allowing rationally localized construction sites and related subprojects, while retaining the remaining development and development area beyond of the negative effect of construction for comfortable living and work.

  10. ToF-SIMS Investigation of the Effectiveness of Acid-Cleaning procedures for Genesis Solar Wind Collectors

    Science.gov (United States)

    Goreva, Y. S.; Humanyun, M.; Burnett, D. S.; Jurewicz, A. J.; Gonzalez, C. P.

    2014-01-01

    ToF-SIMS images of Genesis sample surfaces contain an incredible amount of important information, but they also show that the crash-derived surface contamination has many components, presenting a challenge to cleaning. Within the variability, we have shown that there are some samples which appear to be clean to begin with, e.g. 60471, and some are more contaminated. Samples 60493 and 60500 are a part of a focused study of the effectiveness of aqua regia and/or sulfuric acid cleaning of small flight Si implanted with Li-6 using ToF-SIMS.

  11. The genesis of period-adding bursting without bursting-chaos in the Chay model

    International Nuclear Information System (INIS)

    Yang Zhuoqin; Lu Qishao; Li Li

    2006-01-01

    According to the period-adding firing patterns without chaos observed in neuronal experiments, the genesis of the period-adding 'fold/homoclinic' bursting sequence without bursting-chaos is explored by numerical simulation, fast/slow dynamics and bifurcation analysis of limit cycle in the neuronal Chay model. It is found that each periodic bursting, from period-1 to period-7, is separately generated by the corresponding periodic spiking pattern through two period-doubling bifurcations, except for the period-1 bursting occurring via a Hopf bifurcation. Consequently, it can be revealed that this period-adding bursting bifurcation without chaos has a compound bifurcation structure with transitions from spiking to bursting, which is closely related to period-doubling bifurcations of periodic spiking in essence

  12. Divergent responses of tropical cyclone genesis factors to strong volcanic eruptions at different latitudes

    Science.gov (United States)

    Yan, Qing; Zhang, Zhongshi; Wang, Huijun

    2018-03-01

    To understand the behaviors of tropical cyclones (TCs), it is very important to explore how TCs respond to anthropogenic greenhouse gases and natural forcings. Volcanic eruptions are a major natural forcing mechanism because they inject sulphate aerosols into the stratosphere, which modulate the global climate by absorbing and scattering solar radiation. The number of Atlantic hurricanes is thought to be reduced following strong tropical eruptions, but whether the response of TCs varies with the locations of the volcanoes and the different ocean basins remains unknown. Here, we use the Community Earth System Model-Last Millennium Ensemble to investigate the response of the large-scale environmental factors that spawn TCs to strong volcanic eruptions at different latitudes. A composite analysis indicates that tropical and northern hemisphere volcanic eruptions lead to significantly unfavorable conditions for TC genesis over the whole Pacific basin and the North Atlantic during the 3 years post-eruption, relative to the preceding 3 years. Southern hemisphere volcanic eruptions result in obviously unfavorable conditions for TC formation over the southwestern Pacific, but more favorable conditions over the North Atlantic. The mean response over the Indian Ocean is generally muted and insignificant. It should be noted that volcanic eruptions impact on environmental conditions through both the direct effect (i.e. on radiative forcing) and the indirect effect (i.e. on El Niño-Southern Oscillation), which is not differentiated in this study. In addition, the spread of the TC genesis response is considerably large for each category of eruptions over each ocean basin, which is also seen in the observational/proxy-based records. This large spread is attributed to the differences in stratospheric aerosol distributions, initial states and eruption intensities, and makes the short-term forecast of TC activity following the next large eruption challenging.

  13. Genesis and evolution of the Skyrme model from 1954 to the present

    International Nuclear Information System (INIS)

    Sanyuk, V.I.

    1994-01-01

    Not widely known facts on the genesis of the Skyrme model are presented in a historical survey, based on Skyrme's earliest papers and on his own published remembrance. We consider the evolution of Skyrme's model description of nuclear matter from the ''Mesonic Fluid'' model up to its final version, known as the baryon model. We pay special tribute to some well-known ideas in contemporary particle physics which one can find in Skyrme's earlier papers, such as: Nuclear Democracy, the Solitonic Mechanism, the Nonlinear Realization of Chiral Symmetry, Topological Charges, Fermi-Bose Transmutation, etc. It is curious to note in the final version of the Skyrme model gleams of Kelvin's ''Vortex Atoms'' theory. In conclusion we make a brief analysis of the validity of Skyrme's conjectures in view of recent results and pinpoint some questions which still remain. (author). 93 refs, 4 figs

  14. Response of the Karst Phreatic Zone to Flood Events in a Major River (Bohemian Karst, Czech Republic) and its Implication for Cave Genesis

    Czech Academy of Sciences Publication Activity Database

    Vysoká, H.; Bruthans, J.; Žák, Karel; Mls, J.

    2012-01-01

    Roč. 74, č. 1 (2012), s. 65-81 ISSN 1090-6924 R&D Projects: GA ČR GAP210/10/1760 Institutional research plan: CEZ:AV0Z30130516 Keywords : karst * cave genesis * Bohemian Karst Subject RIV: DB - Geology ; Mineralogy Impact factor: 0.474, year: 2012

  15. Genesis of Hurricane Sandy (2012) Simulated with a Global Mesoscale Model

    Science.gov (United States)

    Shen, Bo-Wen; DeMaria, Mark; Li, J.-L. F.; Cheung, S.

    2013-01-01

    In this study, we investigate the formation predictability of Hurricane Sandy (2012) with a global mesoscale model. We first present five track and intensity forecasts of Sandy initialized at 00Z 22-26 October 2012, realistically producing its movement with a northwestward turn prior to its landfall. We then show that three experiments initialized at 00Z 16-18 October captured the genesis of Sandy with a lead time of up to 6 days and simulated reasonable evolution of Sandy's track and intensity in the next 2 day period of 18Z 21-23 October. Results suggest that the extended lead time of formation prediction is achieved by realistic simulations of multiscale processes, including (1) the interaction between an easterly wave and a low-level westerly wind belt (WWB) and (2) the appearance of the upper-level trough at 200 hPa to Sandy's northwest. The low-level WWB and upper-level trough are likely associated with a Madden-Julian Oscillation.

  16. The geochemistry of marine sediments, island arc magma genesis, and crust-mantle recycling

    International Nuclear Information System (INIS)

    Ben Othman, D.; Paris-6 Univ., 75; White, W.M.; Cornell Univ., Ithaca, NY; Patchett, J.; Arizona Univ., Tucson

    1989-01-01

    To assess the role of sediment subduction and recycling in island arc magma genesis and mantle evolution, we have determined Sr, Nd, and Pb isotope ratios and the concentrations of K, Rb, Cs, Ba, Sr, U, Th, Pb and rare earth elements in 36 modern marine sediments, including Mn nodules, biogenic oozes, and pelagic and hemipelagic clays from the Pacific, Antlantic and Indian Oceans. Sr and Nd isotope ratios and the Sr/Nd concentration ratios in sediments are such that mixing between subducted sediment on the one hand and depleted mantle or subducted oceanic crust on the other can produce mixing arrays which may pass either through or outside of the oceanic basalt Sr-Nd isotope 'mantle array'. Thus whether isotope compositions of island arc volcanics (IAV) plot inside our outside of the mantle array is not a good indication of whether or not their sources contain a subducted sediment component. The presence of subducted sediment in the sources of IAV should lead to Cs/Rb and Pb/Ce ratios which are higher than those in oceanic basalts, and Ba/Rb ratios which may be either higher or lower than oceanic basalts. Simple mixing calculations suggest that as little as a percent or so sediment in island arc magma sources can account for the observed Cs/Rb, Pb/Ce, and Ba/Rb ratios in IAV. However, it does not appear that high Ba/La ratios and negative Ce anomalies in IAV are inherited from sediment in IAV magma sources. It is more likely these features reflect fractionation of alkalis and alkaline earths from rare earths during slab dehydration and metasomatism. Pb isotope ratios in sediments from the Warton Basin south of the Sunda Arc are collinear in 208 Pb/ 204 Pb- 207 Pb/ 204 Pb- 206 Bp/ 204 Pb space with volcanics from West Sunda, but not with volcanics from the East Sunda. This collinearity is consistent with the hypothesis that sediments similar to these are being subducted to the magma genesis zone of the West Sunda Arc. (orig./WB)

  17. Golden Genesis and the Teotonio Vilela Foundation: commercializing PV residential electrification with a not-for-profit partner

    Energy Technology Data Exchange (ETDEWEB)

    D' Addario, P.J. [International Fund for Renewable Energy and Energy Efficiency, New York, NY (United States)

    2000-11-01

    This article presents a case study of a project which provides photovoltaic-based rural electrification in the state of Alagoas in northeastern Brazil. The project, the Luz do Sol Programme (LdS), was initiated in mid-1996 by the Golden Genesis Company (Golden) and the Fundacao Teotonio Vilela (FTV). The article emphasizes some noteworthy characteristics of the project: the partnership between US commercial and Brazilian philanthropic interests; the financial aspect, a dedicated line of credit requiring only the equipment itself as security; and the local ownership and management of system operations, collections, and routine maintenance. In 1996, the Golden Genesis Company had developed a central battery charging system to bring the price of electrification within the range of the rural poor; it financed the US content of the systems, with the Bank of the Northeast of Brazil (BN) financing the Brazilian content. The article traces the long and arduous path to establish the programme, including both bureaucratic and technical challenges. These difficulties brought the project to an impasse in August of 1998, and Golden withdrew. FTV then re-negotiated the agreement with BN, changing the technical approach to individual solar home systems. This improved the situation, and the project has since enjoyed 100% loan repayment rates from the entrepreneurs. In June 1999, BP/Solarex became FTV's new commercial partner. The project currently shows promise of becoming the commercially viable programme originally envisaged by Golden, with commercial and technical decision-making at the local level. (author)

  18. Geological characteristics and genesis of Niangnianggong gold-silver deposit in Liaoning Province, China

    International Nuclear Information System (INIS)

    Hou Zhenyuan

    2013-01-01

    Based on the analysis of geological characteristics and genesis of Niangnianggong deposit, this paper suggested that the deposit is controlled by the EW direction faults and belongs to quartz vein type. Average value of δ 34 S of the ore is 2.19‰, and the variation ranges from 1.6‰ to 4.9‰, which shows the feature of hydrothermal sulfur. The result of lead isotope is fall into original lead zone, which shows the feature of primeval lead system. The result of H-O isotope is close to meteoric line, which means the participation of precipitations. Rb-Sr age of ore is 186.6 Ma, which is similar to the age of diorite dike. Multi-disciplinary analysis concludes that the deposit is a quartz vein type deposit with composite hydrothermal origin. (author)

  19. Dynamical peculiarities of nucleo-genesis of light nuclei on the early stage of the Universe development

    International Nuclear Information System (INIS)

    Takibaev, N.Zh.; Spanova, G.A.

    2003-01-01

    The item of the L group chemical elements nuclei generation on the early stage of the Universe development has been studied. At this stage the thermodynamical equilibrium inside of nucleus, the electromagnetic and the neutrino component are passing at adiabatic matter expand condition. Description of hot hadron substance and light nuclei nucleo-genesis process are considered in the conditions of matter thermodynamical equilibrium. The approach of thermodynamical potential and state equation were used for analysis. The reactions balance in subsystems, including isotope group and neutron medium (for example, reactions in the hydrogen group) is studied. The assessments for disintegration channel influence are given

  20. On gravity's role in the genesis of rest masses of classical fields

    Science.gov (United States)

    Szabados, László B.

    2018-03-01

    It is shown that in the Einstein-conformally coupled Higgs-Maxwell system with Friedman-Robertson-Walker symmetries the energy density of the Higgs field has stable local minimum only if the mean curvature of the t=const hypersurfaces is less than a finite critical value χ _c, while for greater mean curvature the energy density is not bounded from below. Therefore, there are extreme gravitational situations in which even quasi-locally defined instantaneous vacuum states of the Higgs sector cannot exist, and hence one cannot at all define the rest mass of all the classical fields. On hypersurfaces with mean curvature less than χ _c the energy density has the `wine bottle' (rather than the familiar `Mexican hat') shape, and the gauge field can get rest mass via the Brout-Englert-Higgs mechanism. The spacelike hypersurface with the critical mean curvature represents the moment of `genesis' of rest masses.

  1. BASIC LAWS OF DISTRIBUTION AND GENESIS OF PSAMMOPHILOUS COLEOPTERA OF PONTO-CASPIAN REGION IN THE CASE OF TENEBRIONIDAE AND SCARABAEOIDEA (INSECTA: COLEOPTERA)

    OpenAIRE

    M. V. Nabozhenko; I. V. Shokhin; G. M. Abdurahmanov; A. M. Klicheva; A. V. Morakhonich; D. I. Oleinik

    2012-01-01

    The paper deal with migration ways of psammophilous Tenebrionidae and Scarabaeoidea of Ponto-Caspian region since the Pliocene. Reconstruction of genesis of the fauna is made after analyses of contemporary distribution. Zoogeographical analyses of fauna showed the share of species with different distribution in 3 zoogeographical big regions and bassins of Caspian sea, Sea of Azov and Black sea.

  2. GENESIS AND DEVELOPMENT OF A “NONPARTISAN” POLITICAL ACTOR: The Formation of the Jama’ah Islah Malaysia (JIM and its Roots in Western Europe

    Directory of Open Access Journals (Sweden)

    Sophie Lemiere

    2009-02-01

    Full Text Available This paper looks at the genesis and development of the Jama’ah Islah Malaysia (JIM, a modernist-reformist Islamist organisation that today has played a vital and visible role in the political landscape of Malaysian politics. Little is known about the early genesis of JIM, and how it began in the 1970s and 1980s as a student-based cadre organisation, created by Malaysian Muslim students studying abroad in Europe and North America. JIM’s roots therefore lie in the Islamic Representative Council (IRC that was a semi-underground student-cadre movement that was created outside Malaysia, and which aimed to bring about the Islamisation of Malaysian society through the process of social and political mobilisation. Working through the archives of JIM today and interviewing the foundermembers of JIM and the IRC, this paper is the first historical account of the formation and development of IRC and JIM to be published. 

  3. Importance of No. 21 chromosome in translocation t(8:21) in acute myelocytic leukemia (AML) to the genesis of the disease

    Energy Technology Data Exchange (ETDEWEB)

    Ishihara, T; Minamihisamatsu, M

    1986-05-01

    The results are reported of the chromosome analysis of 17 cases of acute myelocytic leukemia (AML), mostly belonging to M2 of the FAB classification, especially on the translocation t(8:21) and its variant translocations. The presence of two cases with simple variant translocation not involving No. 8 chromosome seems to suggest that No. 21 chromosome is more important to the genesis of AML than the No. 8 chromosome. This assumption appears to be supported by findings on cases with complex translocation: In two cases with complex translocation, the portion translocated from No. 21 chromosome onto No. 8 was firmly maintained in the specific site (q21) on No. 8 whereas the portion translocated from No. 8 chromosome onto No. 21 was involved in further translocation with another chromosome, onto which it was re-translocated. The results of the present cytogenetic study indicate that the analysis of variant translocations in various specific chromosome translocations in leukemia and other malignant disorders is very useful to elucidate the problem as to whether the genesis of such disorders lies in either one or both of the pair of chromosomes involved in the specific translocations of the respective diseases.

  4. Between normal and pathological: Ludwik Fleck, Georges Canguilhem and the genesis of historical epistemology

    Directory of Open Access Journals (Sweden)

    Mauro Lucio Leitão Condé

    2016-05-01

    Full Text Available The main purpose of this article is to address, starting from some aspects of the thought of Ludwik Fleck and Georges Canguilhem, the genesis of historical epistemology in the history of science. Specifically, it seeks the contribution of the biological matrix, or the life sciences, presented by these authors, as a central framework in the constitution of historical epistemology. In other words, more than a search of similarities between Fleck and Canguilhem, the main goal is to show how, in formulating independently their ideas of history of science – especially the history of medicine – these authors contributed decisively to the basis of a historical epistemology that will be, throughout the twentieth century, a new thought style for understanding the history of science.

  5. Genesis and identity of «ACN de JP»’s foundational group (1904-1909

    Directory of Open Access Journals (Sweden)

    Pablo Sánchez Garrido

    2017-07-01

    Full Text Available The aim of this essay is to study the genesis of the historical «Asociación Católico-Nacional de Jóvenes Propagandistas» (later, «ACN de P» from its previous gestation and preparation in the congregation of «Luises» in Madrid, between 1904 and 1909. So the article focuses on its action throughout the organ of expression –Hojas Sueltas– and others public meetings. Likewise, this essay has brought to light the identity of all the members of the foundational group of the ACN de JP, because the complete names and biographic notes of these cofounder members was unknown. Finally, the text points out some considerations about the ideological identity of the group.

  6. Role of upper ocean parameters in the genesis, intensification and tracks of cyclones over the Bay of Bengal

    Digital Repository Service at National Institute of Oceanography (India)

    Maneesha, K.; Sadhuram, Y.; Prasad, K.V.S.R.

    of high heat potential (>90 kj/cm2) in the western Gulf of Mexico (Goni et al. 2003, 2009; Shay et al. 2000). Further, Hurricanes Igor (tropical Atlantic) and Celia (Eastern North Pacific), Typhoon Megi (Western North Pacific) and Cyclone Phet (Arabian Sea... 2009/10 in the Gulf of Mexico and the southwestern Pacific Ocean, while there was an increase in the western Pacific Ocean, Arabian Sea and Bay of Bengal. All the above studies emphasize the importance of the UOHC in the genesis and intensification...

  7. Endothelial Progenitor Cell Dysfunction in Polycystic Ovary Syndrome: Implications for The Genesis of Cardiovascular Diseases

    Directory of Open Access Journals (Sweden)

    Yu-Hsun Kao

    2013-01-01

    Full Text Available Polycystic ovary syndrome (PCOS, the most common endocrine disorder affecting women ofreproductive age, is characterized by hyperandrogenism and insulin resistance. Women withPCOS have a higher risk for cardiovascular diseases (CVDs and endothelial dysfunction. Themechanisms underlying these risks are unclear. Human peripheral blood contains circulatingendothelial progenitor cells (EPCs derived from bone marrow that have the ability to proliferate anddifferentiate into mature endothelial cells, which may contribute to vessel homeostasis and repair.PCOS is associated with insulin resistance, hyperinsulinemia, and dyslipidemia, which may resultin EPC dysfunction. In this review, we summarize the potential mechanisms of EPC dysfunction inPCOS, which possibly result in a higher genesis of CVDs in PCOS-affected subjects.

  8. Features of lipid metabolism in chronic heart failure of different genesis with concomitant overweight and obesity

    Directory of Open Access Journals (Sweden)

    Р. P. Bidzilya

    2016-08-01

    Full Text Available Recently clinical studies demonstrated reciprocal association between traditional cardiovascular risk factors, in particular, hyperlipidemia and obesity, with worse clinical outcomes in CHF. Unlike ischemic heart disease (IHD, where high levels of atherogenic and low of antiatherogenic lipids fraction traditionally associated with worsening of prognosis and course of disease, in conditions of the CHF proven negative impact of the reduction of lipid levels and body mass index. Demonstrated the phenomena called "cholesterol paradox" and "obesity paradox". Aim. To study the features of lipid metabolism in CHF of different genesis with concomitant overweight and obesity. Materials and methods. 240 patients with I–III functional class (FC of the disease with concomitant overweight and abdominal obesity I–III degree were examined. FC of the disease was established according to the classification of New York Heart Association (NYHA.Normal, overweight and the degree of abdominal obesity was identified by calculating the body mass index. Etiologic factors of CHF were chronic forms of IHD, arterial hypertension, and/or a combination of both. With the help of biochemical blood tests lipid metabolism were assessed. Results. The maximum values as atherogenic and antiatherogenic lipid indicators are investigated in non-ischemic (hypertensive CHF. Patients with CHF of ischemic genesis are characterized by minimal values of atherogenic fractions of lipids. Patients with combined etiology of CHF occupy the intermediate position of atherogenic fractions content, while they demonstrate the minimum value in the antiatherogenic HDL-cholesterol. Conclusion. Changes of lipid metabolism are varied depending on the etiology of CHF in patients with concomitant overweight and obesity and the most unfavorable in ischemic form of the disease.

  9. The Genesis of Participatory Democracy in Brazil: a Scientific (ReConstruction

    Directory of Open Access Journals (Sweden)

    Marie-Hélène Sa Vilas Boas

    2017-04-01

    Full Text Available The rise of participatory democracy has often been explained by the renewal of collective action in Europe and Latin America. This review essay questions the 'movement-based' genesis of Brazilian participatory democracy by analyzing the idea of the state upon which it rests. It argues that the focus on social movements falls short of explaining the spread of participatory experiments, and that it rests on a simplified understanding of the dynamics of the Brazilian State prior to the 1980s. The argument is developed along three axes. First, the essay analyses how the 'classics' of Brazilian political sociology framed the early studies on participatory democracy. Second, it shows that even if the unifying notion of the state has been challenged, progress has focussed on the study of the democratic period. Third, it presents evidence that participation, as a practical category, was an integral part of the military regime's discourse and practice. Finally, the essay defines lines of investigation to reconsider the origins of participatory democracy in Brazil.

  10. BASIC LAWS OF DISTRIBUTION AND GENESIS OF PSAMMOPHILOUS COLEOPTERA OF PONTO-CASPIAN REGION IN THE CASE OF TENEBRIONIDAE AND SCARABAEOIDEA (INSECTA: COLEOPTERA

    Directory of Open Access Journals (Sweden)

    M. V. Nabozhenko

    2012-01-01

    Full Text Available The paper deal with migration ways of psammophilous Tenebrionidae and Scarabaeoidea of Ponto-Caspian region since the Pliocene. Reconstruction of genesis of the fauna is made after analyses of contemporary distribution. Zoogeographical analyses of fauna showed the share of species with different distribution in 3 zoogeographical big regions and bassins of Caspian sea, Sea of Azov and Black sea.

  11. Sex differences in cell genesis, hippocampal volume and behavioral outcomes in a rat model of neonatal HI.

    Science.gov (United States)

    Waddell, Jaylyn; Hanscom, Marie; Shalon Edwards, N; McKenna, Mary C; McCarthy, Margaret M

    2016-01-01

    Hypoxia-ischemia (HI) of the brain in near-term and term infants is a leading cause of infant mortality and lifelong disability but current therapeutic approaches remain limited. Males consistently display greater vulnerability to the deleterious consequences of HI in both humans and animal models. Neurogenesis increases after neonatal HI and offers a potential therapeutic target for recovery. The steroid hormone estradiol has been extensively explored as a neuroprotectant in adult models of stroke but with mixed results. Less consideration has been afforded to this naturally occurring agent in the developing brain, which has unique challenges from the adult. Using a model of term HI in the rat we have explored the impact of this insult on cell genesis in the hippocampus of males and females and the ability of estradiol treatment immediately after insult to restore function. Both short-term (3 days) and long-term (7 days) post-injury were assessed and revealed that only females had markedly increased cell genesis on the short-term but both sexes were increased long-term. A battery of behavioral tests revealed motor impairment in males and compromised episodic memory while both sexes were modestly impaired in spatial memory. Juvenile social play was also depressed in both sexes after HI. Estradiol therapy improved behavioral performance in both sexes but did not reverse a deficit in hippocampal volume ipsilateral to the insult. Thus the effects of estradiol do not appear to be via cell death or proliferation but rather involve other components of neural functioning. Published by Elsevier Inc.

  12. Sex differences in cell genesis, hippocampal volume and behavioral outcomes in a rat model of neonatal HI

    Science.gov (United States)

    Waddell, Jaylyn; Hanscom, Marie; Edwards, N. Shalon; McKenna, Mary C.; McCarthy, Margaret M.

    2015-01-01

    Hypoxia ischemia (HI) of the brain in near-term and term infants is a leading cause of infant mortality and lifelong disability but current therapeutic approaches remain limited. Males consistently display greater vulnerability to the deleterious consequences of HI in both humans and animal models. Neurogenesis increases after neonatal HI and offers a potential therapeutic target for recovery. The steroid hormone estradiol has been extensively explored as a neuroprotectant in adult models of stroke but with mixed results. Less consideration has been afforded to this naturally occurring agent in the developing brain, which has unique challenges from the adult. Using a model of term HI in the rat we have explored the impact of this insult on cell genesis in the hippocampus of males and females and the ability of estradiol treatment immediately after insult to restore function. Both short-term (3 days) and long-term (7 days) post-injury were assessed and revealed that only females had markedly increased cell genesis on the short-term but both sexes were increased long-term. A battery of behavioral tests revealed motor impairment in males and compromised episodic memory while both sexes were modestly impaired in spatial memory. Juvenile social play was also depressed in both sexes after HI. Estradiol therapy improved behavioral performance in both sexes but did not reverse a deficit in hippocampal volume ipsilateral to the insult. Thus the effects of estradiol do not appear to be via cell death or proliferation but rather involve other components of neural functioning. PMID:26376217

  13. Impact of global warming on tropical cyclone genesis in coupled and forced simulations: role of SST spatial anomalies

    Science.gov (United States)

    Royer, Jean-François; Chauvin, Fabrice; Daloz, Anne-Sophie

    2010-05-01

    The response of tropical cyclones (TC) activity to global warming has not yet reached a clear consensus in the Fourth Assessment Report (AR4) published by the Intergovernmental Panel on Climate Change (IPCC, 2007) or in the recent scientific literature. Observed series are neither long nor reliable enough for a statistically significant detection and attribution of past TC trends, and coupled climate models give widely divergent results for the future evolution of TC activity in the different ocean basins. The potential importance of the spatial structure of the future SST warming has been pointed out by Chauvin et al. (2006) in simulations performed at CNRM with the ARPEGE-Climat GCM. The current presentation describes a new set of simulations that have been performed with the ARPEGE-Climat model to try to understand the possible role of SST patterns in the TC cyclogenesis response in 15 CMIP3 coupled simulations analysed by Royer et al (2009). The new simulations have been performed with the atmospheric component of the ARPEGE-Climat GCM forced in 10 year simulations by the SST patterns from each of 15 CMIP3 simulations with different climate model at the end of the 21st century according to scenario A2. The TC analysis is based on the computation of a Convective Yearly Genesis Parameter (CYGP) and the Genesis Potential Index (GPI). The computed genesis indices for each of the ARPEGE-Climat forced simulations is compared with the indices computed directly from the initial coupled simulation. The influence of SST patterns can then be more easily assessed since all the ARPEGE-Climat simulations are performed with the same atmospheric model, whereas the original simulations used models with different parameterization and resolutions. The analysis shows that CYGP or GPI anomalies obtained with ARPEGE are as variable between each other as those obtained originally by the different IPCC models. The variety of SST patterns used to force ARPEGE explains a large part of

  14. Discrimination and quantification of contamination and implanted solar wind in Genesis collector shards using grazing incidence synchrotron x-ray techniques: Initial results

    International Nuclear Information System (INIS)

    Kitts, K.; Sutton, S.; Eng, P.; Ghose, S.; Burnett, D.

    2006-01-01

    Grazing incidence X-ray fluorescence is a non-destructive technique that can differentiate the embedded solar wind component from surface contamination and collector background in the Genesis shards. Initial solar Fe abundance in D30554 is 8 x 10 12 /cm 2 . Accurate knowledge of the composition of the Sun provides a baseline, which allows an understanding of how the solar system has evolved over time and how solar processes and solar wind mechanics behave. Unfortunately, the errors in photospheric abundances are too large for many planetary science problems and this hampers our understanding of these different processes. Analyses of solar wind implanted in meteorites or lunar soils have provided more precise data but alteration processes on these bodies may complicate such information. In response to this need for pristine solar wind samples, NASA developed and launched the Genesis Probe. Unfortunately, the probe smashed into the Utah desert shattering the 300 collector plates into 15,000+ pieces all of which are now coated in a both a fine terrestrial dust and Si and Ge powder from the disrupted collectors themselves. The solar wind penetration depth is 100-200 nm and the superposed contamination layers are typically 40-50 nm. Stringent cleaning regimes have the potential of removing the solar wind itself. The best solution is to have sufficient spatial resolution to separately analyze the surface contamination and penetrated solar wind. To that end, three Genesis collector array shards and their appropriate flight spares were characterized via grazing incidence x-ray fluorescence and x-ray reflectivity. The goals were (1) to evaluate the various cleaning methods used to eliminate contamination, (2) to identify the collector substrates most suited for this technique, (3) to determine whether the solar wind signature could be deconvolved from the collector background signature, and (4) to measure the relative abundances of Ca to Ge in the embedded solar wind.

  15. Scale genesis and gravitational wave in a classically scale invariant extension of the standard model

    Energy Technology Data Exchange (ETDEWEB)

    Kubo, Jisuke [Institute for Theoretical Physics, Kanazawa University,Kanazawa 920-1192 (Japan); Yamada, Masatoshi [Department of Physics, Kyoto University,Kyoto 606-8502 (Japan); Institut für Theoretische Physik, Universität Heidelberg,Philosophenweg 16, 69120 Heidelberg (Germany)

    2016-12-01

    We assume that the origin of the electroweak (EW) scale is a gauge-invariant scalar-bilinear condensation in a strongly interacting non-abelian gauge sector, which is connected to the standard model via a Higgs portal coupling. The dynamical scale genesis appears as a phase transition at finite temperature, and it can produce a gravitational wave (GW) background in the early Universe. We find that the critical temperature of the scale phase transition lies above that of the EW phase transition and below few O(100) GeV and it is strongly first-order. We calculate the spectrum of the GW background and find the scale phase transition is strong enough that the GW background can be observed by DECIGO.

  16. THE SOMEŞAN PLATEAU LAKES: GENESIS, EVOLUTION AND TERRITORIAL REPARTITION

    Directory of Open Access Journals (Sweden)

    Victor SOROCOVSCHI

    2010-06-01

    Full Text Available The present paper analyzes the genesis of the lake depressions in the Someşan Plateau and the way they evolved in time and space, as well as the morphometric elements characteristic of the different genetic types of lakes. The natural lakes in this region are few and their dimensions are small; they generally appear solitarily and only rarely as lake complexes. In this category have been included the valley lakes, the lakes formed in abandoned meanders and the lakes formed in areas with landslides. The artificial lakes are more numerous and include several genetic types. The most representative are the remnant lakes formed in the depressions resulted from the exploitation of different construction materials (kaolin sands, lime stones and the anthropic salty lakes lakes formed in abandoned salt mines from the diapir area of the Hills of Dej. The rapid evolution of these types of lakes has been highlighted through the comparative analysis of the morphometric elements obtained on the basis of topometric and bathymetric measurements. The lakes arranged for pisciculture include several subtypes (ponds, fish ponds that have been identified and characterized for the fist time, their morphometric elements being determined using digital data bases, satellite images and detailed topometric maps.

  17. Maternal perceptions of their child's weight status: the GENESIS study.

    Science.gov (United States)

    Manios, Yannis; Kondaki, Katerina; Kourlaba, Georgia; Vasilopoulou, Emilia; Grammatikaki, Evangelia

    2009-08-01

    The objective of the present work was to quantify mothers' misclassification of pre-school children's weight status and to determine factors associated with the maternal misperception. A representative sample of 2287 children aged 2-5 years was examined (GENESIS study). Mothers' perceptions of their child's weight status and the children's and mothers' anthropometric and other characteristics (sociodemographic and lifestyle) were recorded. Almost 38 % of mothers underestimated their child's weight status. The frequency of underestimation was much higher among 'at risk of being overweight' and 'overweight' children (88.3 % and 54.5 %, respectively) compared with 'underweight/normal-weight' children (18.0 %, P engaging in physical activity for less than 3 h/week and in children whose mothers had low education status, compared with their counterparts. Moreover, the higher the BMI-for-age Z-score, the greater the odds that the mother would underestimate her child's weight status. The current study demonstrated that more than one-third of mothers misclassify their children's weight status as being lower than the actual. Given that mother's weight perception might be an important determinant of child's body weight development, clinicians and health professionals should help mothers correctly classify their children's weight status, which could potentially help in the early prevention of overweight and obesity.

  18. Characteristics and genesis of Rare Earth Element (REE) in western Indonesia

    Science.gov (United States)

    Handoko, A. D.; Sanjaya, E.

    2018-02-01

    Rare Earth Element (REE) has unique properties that have been used in many hightech applications. The demand of REE increased recently in the world due to its special properties. Although REE concentration in the crust is higher than gold, economically viable deposits are still rare. Reduction of REE exports by China cause increased prices of REE. Due to this condition, exploration of potential REE mines emerged. Indonesia also participates in this phenomenon, and explore the possibility of REE mines in its area. This review will discuss the characteristics and genesis of REE and its occurrence in western Indonesia; focused in Sumatera, Tin Island, and Kalimantan. The review is done based on literature research from several resources about characteristics of rare earth element in general and in the given area. The research shows that the potential REE mines can be found in several different locations in Indonesia, such as Tin Island, Sumatera, and Kalimantan. Most of them are composed of monazite, zircon, and xenotime as rare earth minerals. Monazite iss known for its elevated number of radioactive elements, so study about radioactive content and more environment friendly ore processing becomes compulsory.

  19. GENESIS CONTRADICTIONS OF GENDER APPROACH IN EDUCATION OF CHILDREN

    Directory of Open Access Journals (Sweden)

    Zh. N. Dyuldina

    2016-01-01

    Full Text Available The aim of the investigation is to consider genesis contradictions of gender approach in modern education and training of children and possibilities of its application in an educational system during the newest period of the society development.Methods, results and scientific novelty. The retrospective analysis of the sources has shown that gender approach isn’t new and not studied: on the contrary, separate education and training of boys and girls in the past was a norm and a duty of parents and teachers. However, the reflection of social processes shows the demolition of traditional system of gender stratification; weakening of women’s and men’s polarization of social roles; change of cultural stereotypes of masculinity and femininity; objective changes in the matrimonial relations. Everything listed above brings into focus an investigative search of new approaches to gender education. The essence of the terms «gender», «gender approach» is specified. Despite very long history of gender education (which was cultivated since the most ancient eras of existence of a mankind, insufficient study of this problem is stated now. Special importance of gender aspect in family education is emphasized. The different points of view in understanding of gender approach in modern science are revealed; the main perspective directions of researches on this subject are noted.Practical significance. The materials of the present article can be used in teaching history of pedagogics, gender psychology and gender pedagogics.

  20. Beyond the hypothesis: Theory's role in the genesis, opposition, and pursuit of the Higgs boson

    Science.gov (United States)

    Wells, James D.

    2018-05-01

    The centrally recognized theoretical achievement that enabled the Higgs boson discovery in 2012 was the hypothesis of its existence, made by Peter Higgs in 1964. Nevertheless, there is a significant body of comparably important theoretical work prior to and after the Higgs boson hypothesis. In this article we present an additional perspective of how crucial theory work was to the genesis of the Higgs boson hypothesis, especially emphasizing its roots in Landau's theory of phase transitions and subsequent theoretical work on superconductivity. A detailed description is then given of the opposition to the Higgs boson hypothesis by many researchers, giving evidence to its speculative nature. And finally, it is discussed the importance of theory work in the decades after the hypothesis in order to make possible the experimental discovery of the Higgs boson.

  1. Prolonged oxidative stress down-regulates Early B cell factor 1 with inhibition of its tumor suppressive function against cholangiocarcinoma genesis

    Directory of Open Access Journals (Sweden)

    Napat Armartmuntree

    2018-04-01

    Full Text Available Early B cell factor 1 (EBF1 is a transcription factor involved in the differentiation of several stem cell lineages and it is a negative regulator of estrogen receptors. EBF1 is down-regulated in many tumors, and is believed to play suppressive roles in cancer promotion and progression. However, the functional roles of EBF1 in carcinogenesis are unclear. Liver fluke-infection-associated cholangiocarcinoma (CCA is an oxidative stress-driven cancer of bile duct epithelium. In this study, we investigated EBF1 expression in tissues from CCA patients, CCA cell lines (KKU-213, KKU-214 and KKU-156, cholangiocyte (MMNK1 and its oxidative stress-resistant (ox-MMNK1-L cell lines. The formation of 8-oxo-7,8-dihydro-2′-deoxyguanosine (8-oxodG was used as an oxidative stress marker. Our results revealed that EBF1 expression was suppressed in cancer cells compared with the individual normal bile duct cells at tumor adjacent areas of CCA tissues. CCA patients with low EBF1 expression and high formation of 8-oxodG were shown to correlate with poor survival. Moreover, EBF1 was suppressed in the oxidative stress-resistant cell line and all of CCA cell lines compared to the cholangiocyte cell line. This suggests that prolonged oxidative stress suppressed EBF1 expression and the reduced EBF1 level may facilitate CCA genesis. To elucidate the significance of EBF1 suppression in CCA genesis, EBF1 expression of the MMNK1 cell line was down-regulated by siRNA technique, and its effects on stem cell properties (CD133 and Oct3/4 expressions, tumorigenic properties (cell proliferation, wound healing and cell migration, estrogen responsive gene (TFF1, estrogen-stimulated wound healing, and cell migration were examined. The results showed that CD133, Oct3/4 and TFF1 expression levels, wound healing, and cell migration of EBF1 knockdown-MMNK1 cells were significantly increased. Also, cell migration of EBF1-knockdown cells was significantly enhanced after 17

  2. The understanding of co-owners' rights in the context of the genesis of environmental rights

    Directory of Open Access Journals (Sweden)

    Kudeikina I.

    2014-01-01

    Full Text Available Environmental rights obtain a special importance in the context of real distribution of joint property. The common practice, where the building regulations are applied to legal relationships when carrying out the real distribution of a joint property, is associated with the genesis of environmental rights, but cannot be supported by the doctrine of absolutism of the property rights. In this Article, the author analyzes the legal reasoning and legal consequences of applicability of environmental rights. The essence of real distribution of joint property is the termination of the joint property as a legal act without a target of environmental transformation. The real distribution of joint property is not an action leaving any environmental impacts. The author concludes that the application of the environmental rights to the real distribution of the joint property unreasonably limits the property rights of co-owners.

  3. Comparative study of angio genesis radiopharmaceuticals for melanoma detection

    International Nuclear Information System (INIS)

    Oliveira, Erica Aparecida de

    2011-01-01

    Early diagnosis and treatment of melanoma, a cutaneous tumor with a serious prognosis, is extremely important for optimal clinical outcome. Phage display peptide libraries are a useful screening resource for identifying bioactive peptides that interact with cancer targets. The aim of this study was the evaluation of two technetium-99m tracers for angio genesis detection in melanoma model, using cyclic peguilated pentapeptide with RGD and NGR motifs conjugated with bifunctional chelator MAG3. The conjugated peptides (10 μL of a μg/μL solution) were labeled with technetium-99m using a sodium tartrate buffer. Radiochemical evaluation was done by ITLC and confirmed by HPLC. Partition coefficient was determined and internalization assays were performed in two melanoma cells (B16F10 and SKMEL28). Biodistribution evaluation of the tracers was done in healthy animals at different times and also in mice bearing the tumor cells at 120 min post injection. Blocking studies were also conducted by co-injection of cold peptides. The conjugated showed the same profile in many evaluations. They were radiolabeled with high radiochemical purity (>97%). Both were hydrophilic, with preferential renal excretion. Tumor uptake was higher for human melanoma cells than for murinic melanoma cells, specially for 99m Tc-MAG3-PEG 8 -c(RGDyK) (7.85±±2.34 %ID/g) at 120 min post injection. The performance of 99m Tc-MAG 3 -PEG 8 -c(RGDyk) was much better than NGR tracer concerning human melanoma uptake and might be considered in future investigations focusing radiotracers for melanoma diagnosis. (author)

  4. Genesis of apocarbonatitic titanium metasomatites of the Petyayan-vara rare-earth occurrence (Vuoriyarvi, the Kola Region

    Directory of Open Access Journals (Sweden)

    Kozlov E. N.

    2018-03-01

    Full Text Available The objects of the study are apocarbonatitic titanium metasomatites ("titanium carbonatites" associated with the rare earth carbonatites of the Petyayan-Vara area of the Vuoriyarvi complex (the Kola region. In this paper, the following mechanism for the formation of these rocks has been substantiated based on the agreed results of mineralogical and geochemical studies. Prior to the onset of carbonatite genesis, a fluorine-enriched fluid phase originated in the lower horizons of the complex passed along the deep-permeating fracture system of several hundred meters length up to the level of the modern erosion surface. It transported Al, Fe2+, Mg, Ti, P into the pyroxenites and Si, Ca and Na out of them, as a result of which the pyroxenites were transformed into giant-grained phlogopite rocks – glimmerites. The most probable source of this fluid is alkaline aluminosilicate magma. Then carbonate melts intruded along the same fractures. In the course of carbonatite genesis, F-fluid caused a local migration of K, Al, Si, Fe, P, Ti, Nb, Ta, Zr, Hf and HREE out of glimmerites into igneous dolomite carbonatites, which led to the formation of apocarbonatitic titanium metasomatites. They represent several paragenetic associations superimposed on each other, the mineral composition and the formation sequence of which correspond to the metasomatic column zones directly observed within the contact "carbonatite – altered pyroxenite". The separation of HFSE and REE is controlled by the same metasomatic column: Ti, Nb and Ta were accumulated in titanium carbonatites, i. e. in associations of the frontal and intermediate zones, and Zr, Hf and HREE – in apatitized fields corresponding to the rear zone of the column. Accordingly, the fractionation of these elements occurred due to the "fluid – rock" interaction. Subsequently, the same long-lived fractures served as a channel for REE-Sr-Ba-S fluids, but the recrystallization caused by K

  5. Magma genesis, storage and eruption processes at Aluto volcano, Ethiopia: lessons from remote sensing, gas emissions and geochemistry

    Science.gov (United States)

    Hutchison, William; Biggs, Juliet; Mather, Tamsin; Pyle, David; Gleeson, Matthew; Lewi, Elias; Yirgu, Gezahgen; Caliro, Stefano; Chiodini, Giovanni; Fischer, Tobias

    2016-04-01

    One of the most intriguing aspects of magmatism during the transition from continental rifting to sea-floor spreading is that large silicic magmatic systems develop within the rift zone. In the Main Ethiopian Rift (MER) these silicic volcanoes not only pose a significant hazard to local populations but they also sustain major geothermal resources. Understanding the journey magma takes from source to surface beneath these volcanoes is vital for determining its eruption style and for better evaluating the geothermal resources that these complexes host. We investigate Aluto, a restless silicic volcano in the MER, and combine a wide range of geochemical and geophysical techniques to constrain magma genesis, storage and eruption processes and shed light on magmatic-hydrothermal-tectonic interactions. Magma genesis and storage processes at Aluto were evaluated using new whole-rock geochemical data from recent eruptive products. Geochemical modelling confirms that Aluto's peralkaline rhyolites, that constitute the bulk of recent erupted products, are generated from protracted fractionation (>80 %) of basalt that is compositionally similar to rift-related basalts found on the margins of the complex. Crustal melting did not play a significant role in rhyolite genesis and melt storage depths of ~5 km can reproduce almost all aspects of their geochemistry. InSAR methods were then used to investigate magma storage and fluid movement at Aluto during an episode of ground deformation that took place between 2008 and 2010. Combining new SAR imagery from different viewing geometries we identified an accelerating uplift pulse and found that source models support depths of magmatic and/or fluid intrusion at ~5 km for the uplift and shallower depths of ~4 km for the subsidence. Finally, gas samples collected on Aluto in 2014 were used to evaluate magma and fluid transport processes. Our results show that gases are predominantly emanating from major fault zones on Aluto and that they

  6. Genesis of the "Critical-Acceleration of MOND" and Its Role in "Formation of Structures"

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    Tank H. K.

    2012-10-01

    Full Text Available As an attempt to explain the “flattening of galaxies rotation-curves”, Milgrom proposed a Modification of Newtonian Dynamics MOND, in which he needed a new constant of nature a 0 , termed as “critical-acceleration-of MOND”, in his best-fit empirical formula. But so far it has been an ad-hoc introduction of a new constant. Whereas this article pro- poses: (i a genesis of this constant; (ii explains its recurrences in various physical sit- uations; and (iii its role in determining the size and radii of various structures, like: the electron, the proton, the nucleus-of-atom, the globular-clusters, the spiral-galaxies, the galactic-clusters and the whole universe. In this process we get a new interpretation of “the cosmological-red-shift”, that the linear part of the cosmological-red-shift may not be due to “metric-expansion-of-space”; and even the currently-believed “accelerated- expansion” may be slowing down with time.

  7. A pre-burial adsorption model for the genesis of gold in the Witwatersrand

    International Nuclear Information System (INIS)

    Davidson, R.J.

    1990-01-01

    The chemistry related to the adsorption of gold and uranium onto algal biomass (activated carbon) is related to the genesis of the Witwatersrand. Detrital gold, together with cyanide solubilized as the stable aurocyanide complex. With the subsequent decomposition of the algal deposits, it is surmized that carbon-rich layers having adsorptive properties formed in the conglomerates. Under these conditions, gold (silver) in solution would be adsorbed selectively as the cyanide complex, together with uranium as the carbonate complex. The subsequent burial and compression of the gold-rich conglomerate with temperatures rising to about 400 degrees C would then have reduced the adsorbed gold to the metal in a single segregated gold-silver metal phase. An adsorption model would explain the very consistent trends in the gold-to-silver ratios of individual reefs in the Witwatersrand, which suggest an extensive hydrothermal system approaching isothermal equilibrium. Also, as gold grades increase, so silver grades generally decrease, indicating the sequential displacement of silver by gold as classically obtained with activated carbon. 11 refs., 2 figs., 1 tab

  8. Vertical transfer of radionuclides in soils of different genesis after Chernobyl NPP accident

    International Nuclear Information System (INIS)

    Bakarykava, Zh.; Shagalova, E.; Zhukova, O.

    2003-01-01

    In this paper a vertical transfer of radionuclides in soils of different genesis after Chernobyl NPP accident was studied. Analysis of obtained data revealed that the main content of cesium-137 is located in 0-5 cm layer of turf-podsolic, sandy-loam and loamy soil provided the lack of their humidification, and of light un-bogged (automorphous) soil as well. Cesium-137 penetration into light un-bogged soils with that sings of surplus humidification is approximately 10 cm deep. Strontium-90 as global birth so Chernobyl origin migrates more rapidly than cesium-137 because of less strong bond with soil absorbing complex. Cesium-137 migration coefficients amounted (0.03-0.46)·10 -7 cm 2 /s for a slow component, and for the fast one (0.39-0.67)·10 -7 cm 2 /s. Strontium-90 migration coefficients in the experimented sites, amounted (0.07-0.58)·10 -7 cm 2 /s for a slow component, and for the fast one (0.64-1.28)·10 -7 cm 2 /s. (authors)

  9. Genesis of Microstructures in Friction Stir Welding of Ti-6Al-4V

    Science.gov (United States)

    Tchein, Gnofam Jacques; Jacquin, Dimitri; Coupard, Dominique; Lacoste, Eric; Girot Mata, Franck

    2018-03-01

    This paper is focused on the genesis of microstructures in friction stir welding (FSW) of the Ti-6Al-4V alloy. Several titanium joints, initially prepared with four different preheat treatments, were processed by FSW. Detailed microstructural analyses were performed in order to investigate change in the microstructure during the process. In this work, the FSW processing allows a controlled and stable microstructure to be produced in the stirring zone, regardless of the initial heat treatment or the welding conditions. The welded material undergoes a severe thermomechanical treatment which can be divided into two steps. First, the friction in the shoulder and the plastic strain give rise to the necessary conditions to allow a continuous dynamic recrystallization of the β phase. This operation produces a fine and equiaxed β grain structure. Second, once the pin has moved away, the temperature decreases, and the material undergoes a heat treatment equivalent to air quenching. The material thus exhibits a β → β + α transformation with germination of a fine intergranular Widmanstätten phase within the ex-fully-recrystallized-β grains.

  10. Genesis of Microstructures in Friction Stir Welding of Ti-6Al-4V

    Science.gov (United States)

    Tchein, Gnofam Jacques; Jacquin, Dimitri; Coupard, Dominique; Lacoste, Eric; Girot Mata, Franck

    2018-06-01

    This paper is focused on the genesis of microstructures in friction stir welding (FSW) of the Ti-6Al-4V alloy. Several titanium joints, initially prepared with four different preheat treatments, were processed by FSW. Detailed microstructural analyses were performed in order to investigate change in the microstructure during the process. In this work, the FSW processing allows a controlled and stable microstructure to be produced in the stirring zone, regardless of the initial heat treatment or the welding conditions. The welded material undergoes a severe thermomechanical treatment which can be divided into two steps. First, the friction in the shoulder and the plastic strain give rise to the necessary conditions to allow a continuous dynamic recrystallization of the β phase. This operation produces a fine and equiaxed β grain structure. Second, once the pin has moved away, the temperature decreases, and the material undergoes a heat treatment equivalent to air quenching. The material thus exhibits a β → β + α transformation with germination of a fine intergranular Widmanstätten phase within the ex-fully-recrystallized- β grains.

  11. Experimental approbation of a new ultrosound contrast agent based on sulfur geksafluoride in diagnostics of focal liver lesions of inflammatory genesis

    Directory of Open Access Journals (Sweden)

    S. V. Fomina

    2017-01-01

    Full Text Available Purpose of the study. Experimental approbation of a new domestic ultrasound contrast agent (UCA based on sulfur hexafluoride in the diagnosis of focal liver lesions of inflammatory genesis.Materials and methods. The investigated ultrasound contrast agent (UCA was a heterogeneous gas-liquid system consisting of micro bubbles of a sparingly soluble gas of sulfur hexafluoride (SF6 surrounded by a flexible mobile membrane of surfactants. Experimental work was carried out on rabbits. The study group included rabbits of males and females with focal liver lesion of inflammatory genesis (n = 12 weighing 1500- 1700 g. UCA was administered to animals in the ear vein. Focal lesions of the liver in animals were created in the experimental laboratory conditions. 14 days after the operation, all animals were subjected to ultrasound examination of the surgical intervention zones by using the Toshiba Aplio 400 scanners (Japan with a 3,5–8 MHz convection sensor. In a natural study, the size, structure and echogenicity of the focus were assessed, the degree of vascularization, the evenness and clarity of the contours were determined. When performing post contrast ultrasound, the time of the onset of contrast enhancement, the total duration of contrast, the changes in the contrast enhancement of the focus in different phases of the study were measured, the dimensions of the focus were measured, and the evenness and acuity of contours were measured. For histological examination, liver fragments and lungs were used. 

  12. Genesis of petroduric and petrocalcic horizons in Latinamerica volcanic soils

    Science.gov (United States)

    Quantin, Paul

    2010-05-01

    Introduction. In Latinamerica, from Mexico to Chile, there are indurated volcanic soils horizons, named 'tepetate' in Mexico or cangahua in the Andes Mountains. Apart from original volcanic tuffs, these horizons were produced by pedogenesis: either through a former weathering of volcanic ash layers into fragic and later to petrocalcic horizons; or after a former soil formation through a second process of transformation from clayey volcanic soils to silicified petroduric horizons. This oral presentation will briefly deal with the formation of petroduric horizons in Mexico and petrocalcic horizon in Ecuador. Petroduric horizon genesis in Mexico. A soil climato-toposequence, near to Veracruz (Rossignol & Quantin, 1997), shows downwards an evolution from a ferralic Nitisol to a petroduric Durisol. A Durisol profile comports these successive horizons: at the top A and Eg, then columnar Btg-sim, laminar Bt-sim , prismatic Bsim, plinthite Cg, over andesite lava flow. Among its main features are especially recorded: clay mineralogy, microscopy and HRTEM. These data show: an increase in cristobalite at the expenses of 0.7 nm halloysite in Egsiltans, laminar Bt-sim, around or inside the columns or prisms of Btg-sim and Bsimhorizons. HRTEM (Elsass & al 2000) on ultra thin sections reveals an 'epigenesis' of clay sheets by amorphous silica, to form successively A-opal, Ct-opal and microcrystalline cristobalite. From these data and some groundwater chemical analyses, a scenario of duripan formation from a past clayey Nitisol is inferred: clay eluviation-illuviation process? alternate redoximorphy? clay degradation, Al leaching and Si accumulation, to form successively A-opal, Ct-opal and cristobalite. Petrocalcic horizon genesis in Ecuador. A soil climato-toposequence on pyroclastic flows, near to Bolivar in Ecuador (Quantin & Zebrowski, 1997), shows downwards the evolution from fragic-eutric-vitric Cambisols to petrocalcic-vitric Phaeozems, at the piedmont under semi

  13. GENESIS OF KHARKOV MUSIC CULTURE IN THE HIGHLIGHT OF THE CITY’S EDUCATION AND CONCERT LIFE FORMATION

    Directory of Open Access Journals (Sweden)

    Olena Kononova

    2016-02-01

    Full Text Available The article highlights the genesis of Kharkov musical culture from the late 18th to the first half of the 19th century, studying it in terms of two aspects, the formation of education and the emergence of the city’s concert life.The relevance of the research subject chosen by the author is determined by the wish to give the fullest description of the multi-layered process of formation of Kharkov musical culture which played one of the leading roles in the history of Ukrainian culture, and to acquaint the Western public with the most interesting facts of the formation and development of a reputable East-European centre. The main range of issues discussed in the article covers the period of the innitial foundation of artistic education, and its influence on the expansion and perception of music in different social circles, presenting the structures and forms of the nascent musical life of Kharkov. The section "Specific features of the Ukrainian system of education" brings out the facts which indicate the progressive tendencies in education, especially, on the territory of Sloboda Ukraine. The formation of artistic education in the religious schools of the city is covered in the section "Genesis of musical education in Kharkov". One of the most productive periods of the city’s cultivation of concert life associated with the functioning of the University is analyzed in the section "The impact of the University music activities on the city's concert going." The Conclusion emphasizes the interaction of traditional and nontraditional in the musical culture of Kharkov that was clearly manifested in the concert activities of the University, in particular, in popularization of oratorios. Furthermore, it discusses the factors which participated in the development in the field of compositional achievement as well as the performing arts and opened new perspectives in the dynamics of the artistic life of the Ukrainian city.

  14. The genesis of the ore hosting 'dolomitic marble' in the Bayan Obo deposit, Inner Mongolia, China: constrained by isotopic results

    International Nuclear Information System (INIS)

    Ding Tiping; Tian Shihong; Wang Defang; Jiang Shaoyong; Bai Ruimei

    2003-01-01

    The Bayan Obo Fe-REE-Nb ore deposit, Inner Mongolia, China is a super large REE deposit. This deposit attracts attentions of many geologists and geochemists for its unique geological characters and geotectonic background. However, there are quite a number of controversies on various aspects of its genesis, such as when the ore deposit was formed, where the ore forming materials came from and what conditions and geotectonic environment the deposit was formed. Among them, the genesis of ore bearing 'dolomitic marble' is a focus point of debating. isotopic methods are important tools for study on ore deposits. Therefore, supplemental stable isotope investigation was undertaken in this study to reach more information on the forming conditions of 'dolomitic marble'. The high contents of REE and Nb, the REE distribution pattern, the low initial 87 Sr/ 86 Sr ratio and low δ 30 Si values of trace silica in 'dolomitic marble' all indicate its magmatic origin. The high δ 18 O values of carbonate and silicate minerals, and the relatively high δ 34 S values indicate that this rock had experienced isotopic exchange with sea water, implying their submarine volcanic origin. The δ 13 C values observed in carbonate and silicate minerals can also be explained by carbonatite assimilated by oceanic carbonate. Therefore, based on its isotopic characters, the 'dolomitic marble' is more likely of volcanic carbonatite rock formed during middle Proterozoic era. (authors)

  15. [The impact of germ theory in the genesis of cancer. Consequences for surgical treatment in the victorian era].

    Science.gov (United States)

    Pereira Poza, A

    1998-01-01

    We use texts by preeminent figures in Victorian surgery at the end of the nineteenth century and information about their role in disseminating the germ theory to analyse the impact of this new etiologic element in the genesis of cancer. We trace the career of William Watson Cheyne (1852-1932), a disciple of Lister, and of many other surgeons of his generation, to outline the changes in the approach to treatment for cancer, the theoretical basis for these changes, and the role of a new conceptualization of cancer in the light of the microbial theory. This theory, among many other better-known factors, helped establish the foundation for radical surgery which became widespread in oncological treatment during the final decade of the nineteenth century.

  16. Building an outpatient imaging center: A case study at genesis healthcare system, part 2.

    Science.gov (United States)

    Yanci, Jim

    2006-01-01

    In the second of 2 parts, this article will focus on process improvement projects utilizing a case study at Genesis HealthCare System located in Zanesville, OH. Operational efficiency is a key step in developing a freestanding diagnostic imaging center. The process improvement projects began with an Expert Improvement Session (EIS) on the scheduling process. An EIS session is a facilitated meeting that can last anywhere from 3 hours to 2 days. Its intention is to take a group of people involved with the problem or operational process and work to understand current failures or breakdowns in the process. Recommendations are jointly developed to overcome any current deficiencies, and a work plan is structured to create ownership over the changes. A total of 11 EIS sessions occurred over the course of this project, covering 5 sections: Scheduling/telephone call process, Pre-registration, Verification/pre-certification, MRI throughput, CT throughput. Following is a single example of a project focused on the process improvement efforts. All of the process improvement projects utilized a quasi methodology of "DMAIC" (Define, Measure, Analyze, Improve, and Control).

  17. Hebb and Cattell: The Genesis of the Theory of Fluid and Crystallized Intelligence

    Science.gov (United States)

    Brown, Richard E.

    2016-01-01

    Raymond B. Cattell is credited with the development of the theory of fluid and crystallized intelligence. The genesis of this theory is, however, vague. Cattell, in different papers, stated that it was developed in 1940, 1941 or 1942. Carroll (1984, Multivariate Behavioral Research, 19, 300-306) noted the similarity of Cattell's theory to “Hebb's notion of two types of intelligence,” which was presented at the 1941 APA meeting, but the matter has been left at that. Correspondence between Cattell, Donald Hebb and George Humphrey of Queen's University, Kingston, Ontario, however, indicates that Cattell adopted Hebb's ideas of intelligence A and B and renamed them. This paper describes Hebb's two types of intelligence, and shows how Cattell used them to develop his ideas of crystallized and fluid intelligence. Hebb and Cattell exchanged a number of letters before Cattell's paper was rewritten in such a way that everyone was satisfied. This paper examines the work of Hebb and Cattell on intelligence, their correspondence, the development of the ideas of fluid and crystallized intelligence, and why Cattell (1943, p. 179) wrote that “Hebb has independently stated very clearly what constitutes two thirds of the present theory.” PMID:28018191

  18. Hebb and Cattell: The Genesis of the Theory of Fluid and Crystallized Intelligence.

    Science.gov (United States)

    Brown, Richard E

    2016-01-01

    Raymond B. Cattell is credited with the development of the theory of fluid and crystallized intelligence. The genesis of this theory is, however, vague. Cattell, in different papers, stated that it was developed in 1940, 1941 or 1942. Carroll (1984, Multivariate Behavioral Research, 19, 300-306) noted the similarity of Cattell's theory to "Hebb's notion of two types of intelligence," which was presented at the 1941 APA meeting, but the matter has been left at that. Correspondence between Cattell, Donald Hebb and George Humphrey of Queen's University, Kingston, Ontario, however, indicates that Cattell adopted Hebb's ideas of intelligence A and B and renamed them. This paper describes Hebb's two types of intelligence, and shows how Cattell used them to develop his ideas of crystallized and fluid intelligence. Hebb and Cattell exchanged a number of letters before Cattell's paper was rewritten in such a way that everyone was satisfied. This paper examines the work of Hebb and Cattell on intelligence, their correspondence, the development of the ideas of fluid and crystallized intelligence, and why Cattell (1943, p. 179) wrote that "Hebb has independently stated very clearly what constitutes two thirds of the present theory."

  19. Obesity and television watching in preschoolers in Greece: the GENESIS study.

    Science.gov (United States)

    Manios, Yannis; Kourlaba, Georgia; Kondaki, Katerina; Grammatikaki, Evangelia; Anastasiadou, Anastasia; Roma-Giannikou, Eleytheria

    2009-11-01

    The aim of the current work was to evaluate the effect of preschoolers' television (TV) watching time on the prevalence of obesity even after controlling for their total energy intake and their physical activity status. A representative sample of 2,374 Greek children aged 1-5 years was examined ("Growth, Exercise and Nutrition Epidemiological Study in preSchoolers", GENESIS study). Children's TV watching time on a usual weekday and at a usual weekend was recorded. The overall mean of children's TV viewing time was 1.32 h/day. The majority of participants (74.0%) spent 4 h/day in front of a TV set. Overall, 65.2% of participants were normal weight, 17.2% were overweight, and the rest 17.6% were obese. The prevalence of obesity was significantly higher among those with TV viewing time >or=2 h/day (21.7%) compared to those watching TV characteristics and physical activity status) only among children aged 3-5 years. However, further adjusting for children's total energy intake revealed that the association between the TV viewing time and the probability of being obese was no longer statistically significant. On the other hand, physical activity status continued to be an independent factor of being obese. The current findings support the hypothesis that the effect of TV viewing time on childhood obesity is independent of physical activity status and may be attributed to the increased total energy intake during TV watching.

  20. Genesis of Karl Popper's EPR-like experiment and its resonance amongst the physics community in the 1980s

    Science.gov (United States)

    Del Santo, Flavio

    2018-05-01

    I present the reconstruction of the involvement of Karl Popper in the community of physicists concerned with foundations of quantum mechanics, in the 1980s. At that time Popper gave active contribution to the research in physics, of which the most significant is a new version of the EPR thought experiment, alleged to test different interpretations of quantum mechanics. The genesis of such an experiment is reconstructed in detail, and an unpublished letter by Popper is reproduced in the present paper to show that he formulated his thought experiment already two years before its first publication in 1982. The debate stimulated by the proposed experiment as well as Popper's role in the physics community throughout 1980s is here analysed in detail by means of personal correspondence and publications.

  1. On the genesis of spike-wave oscillations in a mean-field model of human thalamic and corticothalamic dynamics

    International Nuclear Information System (INIS)

    Rodrigues, Serafim; Terry, John R.; Breakspear, Michael

    2006-01-01

    In this Letter, the genesis of spike-wave activity-a hallmark of many generalized epileptic seizures-is investigated in a reduced mean-field model of human neural activity. Drawing upon brain modelling and dynamical systems theory, we demonstrate that the thalamic circuitry of the system is crucial for the generation of these abnormal rhythms, observing that the combination of inhibition from reticular nuclei and excitation from the cortical signal, interplay to generate the spike-wave oscillation. The mechanism revealed provides an explanation of why approaches based on linear stability and Heaviside approximations to the activation function have failed to explain the phenomena of spike-wave behaviour in mean-field models. A mathematical understanding of this transition is a crucial step towards relating spiking network models and mean-field approaches to human brain modelling

  2. Functional MRI: Genesis, State of the art and the Sequel

    International Nuclear Information System (INIS)

    Bharath, Rose Dawn

    2014-01-01

    The last 25 years have seen functional magnetic resonance imaging (fMRI) grow from an interesting experimental imaging technique in the hands of some to a primary investigation of choice in the localization and lateralization of brain function prior to surgery. Developments in the field of computational neurosciences have transformed fMRI analysis from classical subtractive type analysis to dynamic casual modeling, and now to graph theory analysis. This has widened the scope of fMRI, and is therefore finding applications in understanding neural correlates of diseases like autism and Alzheimer's disease, prognostication of diseases like traumatic brain injury, and has the potential to direct therapy. It is unfortunately true that this widened ambit has not received the clinical attention it deserves, probably because fMRI is susceptible to artifacts from skull base and blood products and has reduced sensitivity in patients with vascular malformations, or because a change in medical practice usually lags behind the technological and scientific developments that make it possible. This review focuses on the developmental chronology of fMRI image analysis in the last 25 years with highlights on major milestones like developments in the field of paradigms, analysis methods, resting state fMRI, and functional connectivity. To make the statistical images of brain at work more colorful, the article starts with genesis of fMRI and ends with the hope of a promising bright future. Many inputs for this article are obtained from a series of 103 review articles edited by Bandettini et al., compiling personal experiences of pioneers in this field. Interested readers are encouraged to refer to these for a more complete overview.

  3. Remarkable Women in a Remarkable Age. On the Genesis of the English Public Sphere, 1642-1752

    Directory of Open Access Journals (Sweden)

    Eleonora Cappuccilli

    2015-06-01

    Full Text Available During the era of the English Revolutions and shortly after that, some spaces, albeit limited, of female visibility open up. Thanks to the window of opportunity caused by the collapse of censorship, the participation in the radical sects and in the Civil war, some remarkable women succeed in introducing themselves in the public sphere, shaping it since its very genesis. Moreover, analysing law institutions as jointure and feoffment, the attempt is to reconstruct some fragments of juridical female autonomy, which belie the total pervasiveness of coverture in the XVII century. As in private law, in public law women, in the role of queens, gain centrality: the principle of female authority, while safeguards the holding of the monarchical regime, destabilizes its patriarchal structure. Going through the works of Katherine Chidley, Margaret Cavendish, Damaris Masham and Mary Astell, the essay aims at reconstructing women's public voice, a voice which upsets the consolidated frames and subverts the established positions, questioning the same social hierarchies.

  4. COMPOSITION, CHARACTERISTICS OF THE ENVIRONMENT, CHOROLOGY AND GENESIS OF SNOUT BEETLES OF PTOCHUS SCHOENH GENUS AND CREATION OF MAPS OF THEIR AREAS IN THE REPUBLIC OF DAGHESTAN

    Directory of Open Access Journals (Sweden)

    Asiyat M. Mukhtarova

    2017-01-01

    Full Text Available Abstract. Aim. The aim of the work was to study the characteristics of the ecology, the chorology and genesis of thesnout beetles of Ptochus genus in Dagestan, as well as designing the maps of their ranges. Materials and methods. The work was based on the materials of expedition and ecology-faunistic studies conducted from 1999 to 2017 in various regions of Dagestan using the basic entomological methods. For mapping were used the following source materials: the database created by the authors for the study group, the map of the Republic of Dagestan taken fromthe National Atlas of Russia, topographic maps from MapInfo 15.2 and maps made in Adobe Illustrator CreativeCloud. Results. The characteristics of the ecology and geographic distribution of the snout beetles of Ptochus genus in Dagestan have been studied; the following maps are created: "The areas of the snout beetles of Ptochus genus of Dagestan" and "The areas of the snout beetles of Ptochus genus of the Botlikh trench of Dagestan". Conclusion. In the fauna of Dagestan, 7 species of Ptochus snout beetles, associated with arid steppe and semidesert landscapes,ed distribution maps and bioecological features, a hypothesis was put forward on the genesis of the study group in the territory of Dagestan.

  5. The genesis of cerebellar GABAergic neurons: fate potential and specification mechanisms

    Directory of Open Access Journals (Sweden)

    Ketty eLeto

    2012-02-01

    Full Text Available The variety of neuronal phenotypes that populate the cerebellum derives from progenitors that proliferate in two germinal neuroepithelia: the ventricular zone generates GABAergic neurons, whereas the rhombic lip is the origin of glutamatergic types. Progenitors of the ventricular zone produce GABAergic projection neurons (Purkinje cells and nucleo-olivary neurons at the onset of cerebellar neurogenesis. Later on, however, these progenitors migrate into the prospective white matter, where they continue to divide up to postnatal development and generate different categories of inhibitory interneurons, according to precise spatio-temporal schedules. Projection neurons derive from discrete progenitor pools located in distinct microdomains of the ventricular zone, whereas interneurons originate from a single population of precursors, distinguished by the expression of the transcription factor Pax-2. Heterotopic/heterochronic transplantation experiments indicate that interneuron progenitors maintain full developmental potentialities up to the end of cerebellar development and acquire mature phenotypes under the influence of environmental cues present in the prospective white matter. Furthermore, the final fate choice occurs in postmitotic cells, rather than dividing progenitors. Extracerebellar cells grafted to the postnatal cerebellum are not responsive to local neurogenic cues and fail to adopt clear cerebellar identities. On the other hand, cerebellar cells grafted to extracerebellar regions retain typical phenotypes of cerebellar GABAergic interneurons, but acquire specific traits under the influence of local cues. These findings indicate that interneuron progenitors are multipotent and sensitive to spatio-temporally patterned environmental signals that regulate the genesis of different categories of interneurons, in precise quantities and at defined times and places.

  6. Israel state implementation and the genesis of conflict Israeli/arab

    Directory of Open Access Journals (Sweden)

    Luciano Kneip Zucchi

    2014-12-01

    Full Text Available We aimed to demonstrate mainly through historical analysis and international politics, the genesis of the conflict in the middle east between jews and arabs, is embedded within a global context and has its heart in imperialist interests and also the bipolarity emerged after world war ii world, and not in rivalry or hatred between secular people, although the ethnic/religious discourse has often succeeded mask the reality of this antagonism, originating in the twentieth century, which entered the xxi no prospect of resolution. history shows that, on the one hand, jews and arabs had some "conflicting interinsti'', especially at the dawn of islam, on the other hand, lived peacefully and productively for centuries, as the umayyad caliphate in spain and elsewhere. History shows that, on the one hand, Jews and Arabs had some "conflicting Interinsti'', especially at the dawn of Islam, on the other hand, lived peacefully and productively for centuries, as the Umayyad Caliphate in Spain and elsewhere. The proclamation of the State of Israel in 1948, although it had set up a compromise solution to the problem anti/Semitic in Europe, redound, however, and paradoxically, a new strangeness and new conflicts now between Jewish and Arab inhabitants of Palestine and throughout the Middle East. The European powers, in this context, flow into a contradiction that your in the same motion that reiterated their prejudices, transporting them to the Middle East and, worsening noticeably with the Cold War and the confrontation between the United States and Soviet Union, which will make region – rich in essential energy resources to the West – the scene of their confrontation, making worse a situation was already desperate in the extreme.

  7. A minimal model of the Atlantic Multidecadal Variability: its genesis and predictability

    Energy Technology Data Exchange (ETDEWEB)

    Ou, Hsien-Wang [Lamont-Doherty Earth Observatory of Columbia University, Department of Earth and Environmental Sciences, Palisades, NY (United States)

    2012-02-15

    Through a box model of the subpolar North Atlantic, we examine the genesis and predictability of the Atlantic Multidecadal Variability (AMV), posited as a linear perturbation sustained by the stochastic atmosphere. Postulating a density-dependent thermohaline circulation (THC), the latter would strongly differentiate the thermal and saline damping, and facilitate a negative feedback between the two fields. This negative feedback preferentially suppresses the low-frequency thermal variance to render a broad multidecadal peak bounded by the thermal and saline damping time. We offer this ''differential variance suppression'' as an alternative paradigm of the AMV in place of the ''damped oscillation'' - the latter generally not allowed by the deterministic dynamics and in any event bears no relation to the thermal peak. With the validated dynamics, we then assess the AMV predictability based on the relative entropy - a difference of the forecast and climatological probability distributions, which decays through both error growth and dynamical damping. Since the stochastic forcing is mainly in the surface heat flux, the thermal noise grows rapidly and together with its climatological variance limited by the THC-aided thermal damping, they strongly curtail the thermal predictability. The latter may be prolonged if the initial thermal and saline anomalies are of the same sign, but even rare events of less than 1% chance of occurrence yield a predictable time that is well short of a decade; we contend therefore that the AMV is in effect unpredictable. (orig.)

  8. Just emotions: Reading the Sarah and Hagar narrative (Genesis 16, 21 through the lens of human dignity

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    Juliana Claassens

    2013-09-01

    Full Text Available This article seeked to read the interconnected narratives of Sarah and Hagar (Genesis 16, 21 in terms of the hermeneutical lens of human dignity. For the purpose of this article, recent studies on the performative nature of emotions, which considered the central role of emotions such as pain, disgust and hatred in shaping the lives of individuals as well as the ways in which people relate to one another, were helpful in contemplating the situations of dehumanisation faced by both Sarah and Hagar as well as the broader question regarding upholding human worth in a context of indignity. This article furthermore considered the role of emotions in a conversation on ethics and particularly the way in which the narrative offered a fruitful avenue for considering Israel�s relationship to their neighbours � a line of interpretation that holds potential for reflecting on complex interracial and interethnic relationships in today�s global context.

  9. Cadet Education in the Imperial Russia: Genesis, Dialectics and the Role in Social Structure of the Society

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    Alexander P. Abramov

    2014-06-01

    Full Text Available The article, using historic and sociological material, presents genesis, dialectics and the role of cadet education of the imperial Russia in the social structure of the society, its weak and strong aspects, determines major stratified features of its graduates. The author notes that the realization of the practice of professional socialization in cadet corps in certain historical period is determined by the social conditions and the factors of the development of the society, its structure and environment, reproducing the modal personality of the future officer. The professional environment of the cadet education in the imperial Russia is defined as closed, line, self-organizing system. Such environment provided the graduates with high social status and prestige in different fields, defined by generic characteristics (affiliation to nobility. Along with high educational and cultural level, modal personality of the graduate is characterized by aloofness from the juniors and subordinates, individualism and careerism, certain closedness towards one’s nation and other social groups.

  10. Preliminary discussion on possible genesis of crustal rotation, its impact on geotectonic evolution and its relation to large-scale metallogeny in Hunan province and adjacent regions

    International Nuclear Information System (INIS)

    Shu Xiaojing

    2005-01-01

    Hunan province and adjacent regions show ring-form distribution features both on surface geologic structure and geophysical field. Such features might result from the rotation movement of the earth crust and exert serious impact on the geotectonic evolution and large-scale metallogeny in Hunan province and adjacent regions. This paper makes a preliminary discussion on the possible genesis of such rotation movement, as well as the associated series of geologic processes and its relation to large-scale metallogeny in Hunan province and adjacent regions. (authors)

  11. Hydrogeochemistry and Genesis Analysis of Thermal and Mineral Springs in Arxan, Northeastern China

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    Xiaomin Gu

    2017-01-01

    Full Text Available In this work, the hydrogeochemistry and environmental isotopic compositions of thermal and mineral springs in Arxan, northeastern China, were used to assess the genesis of the thermal system hosted by deep-seated faults. The reservoir temperature was calculated using the mineral saturation index and geothermometers. According to isotopic analysis, the spring water was of meteoric origin. Sixteen springs in the Arxan geothermal system with outlet temperatures ranging from 10.9 to 41.0 °C were investigated. The water samples can be classified into four groups by using a Piper diagram. The aquifer in which the Group I and Group III samples were obtained was a shallow cold aquifer of the Jurassic system, which is related to the local groundwater system and contains HCO3–Ca·Na groundwater. The Group II and Group IV samples were recharged by deeply circulating meteoric water with HCO3–Na and HCO3·SO4–Na·Ca groundwater, respectively. The springs rise from the deep basement faults. The estimated thermal reservoir temperature is 50.9–68.8 °C, and the proportion of shallow cold water ranges from 54% to 87%. A conceptual flow model based on hydrogeochemical results and hydrogeological features is given to describe the geothermal system of the Arxan springs.

  12. Genesis of sandstone-type uranium deposits in the Sierra Pintada district, Mendoza, Argentina: a Moessbauer study

    International Nuclear Information System (INIS)

    Labenski, F.; Saragovi-Badler, C.

    1982-01-01

    The genesis of sandstone-type uranium deposits in the Cochico Group (Permo-Triassic) of the Sierra Pintada district, San Rafael, Mendoza, has been studied. This is the most important uranium district in Argentina. Uranium sources, uranium transport and precipitation are discussed. Uraninite and brannerite, the main uranium minerals, occur within the matrix of sandstone. Several phenomena can be deduced regarding the depositional environment. Where oxygen was available, precipitation of hydrated ferric oxides occurred; γFe 2 O 3 .nH 2 O varieties (identified by Moessbauer spectroscopy) precipitated in the upper levels of the aquifer, where CO 2 partial pressure was lower, giving reddish or reddish-brown beds. The CO 2 partial pressure also determines the distribution of biogenic agents such as bacteria. Bacteria thus find a more favourable environment for their development and action in upper levels of an aquifer. In the corresponding horizons local reduction occurred where UO 2 precipitated; therefore the highest uranium concentrations correspond to sandstone levels with reddish or reddish-brown pigment. These pigments have been identified by Moessbauer spectroscopy. (Auth.)

  13. Gap Junctions Contribute to Ictal/Interictal Genesis in Human Hypothalamic Hamartomas

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    Jie Wu

    2016-06-01

    Full Text Available Human hypothalamic hamartoma (HH is a rare subcortical lesion associated with treatment-resistant epilepsy. Cellular mechanisms responsible for epileptogenesis are unknown. We hypothesized that neuronal gap junctions contribute to epileptogenesis through synchronous activity within the neuron networks in HH tissue. We studied surgically resected HH tissue with Western-blot analysis, immunohistochemistry, electron microscopy, biocytin microinjection of recorded HH neurons, and microelectrode patch clamp recordings with and without pharmacological blockade of gap junctions. Normal human hypothalamus tissue was used as a control. Western blots showed increased expression of both connexin-36 (Cx36 and connexin-43 (Cx43 in HH tissue compared with normal human mammillary body tissue. Immunohistochemistry demonstrated that Cx36 and Cx43 are expressed in HH tissue, but Cx36 was mainly expressed within neuron clusters while Cx43 was mainly expressed outside of neuron clusters. Gap-junction profiles were observed between small HH neurons with electron microscopy. Biocytin injection into single recorded small HH neurons showed labeling of adjacent neurons, which was not observed in the presence of a neuronal gap-junction blocker, mefloquine. Microelectrode field recordings from freshly resected HH slices demonstrated spontaneous ictal/interictal-like discharges in most slices. Bath-application of gap-junction blockers significantly reduced ictal/interictal-like discharges in a concentration-dependent manner, while not affecting the action-potential firing of small gamma-aminobutyric acid (GABA neurons observed with whole-cell patch-clamp recordings from the same patient's HH tissue. These results suggest that neuronal gap junctions between small GABAergic HH neurons participate in the genesis of epileptic-like discharges. Blockade of gap junctions may be a new therapeutic strategy for controlling seizure activity in HH patients.

  14. Discrimination and quantification of implanted solar wind in Genesis collector shards using grazing incidence synchrotron x-ray techniques: New detector initial results

    International Nuclear Information System (INIS)

    Kitts, K.; Choi, Y.; Sutton, S.R.; Ghose, S.; Burnett, D.; Eng, P.

    2008-01-01

    Accurate knowledge of the composition of the Sun provides a baseline, which allows an understanding of how the solar system has evolved over time and how solar processes and solar wind mechanics behave. Unfortunately, the errors in photospheric abundances are too large for many planetary science problems and this hampers our understanding of these different processes. Analyses of solar wind implanted in meteorites or lunar soils have provided more precise data [e.g. 1 and references therein] but the extent to which alteration processes on these bodies complicate such information is only now being determined. Therefore, in order to obtain pristine solar wind samples, NASA developed and launched the Genesis Discovery Mission. Unfortunately, the probe crash-landed shattering the 300 collector plates into 15,000+ pieces complicating the analysis and necessitating the development of new analytical techniques and equipment. Thus, shards from the Genesis collector array and their appropriate flight spares are currently being characterized via grazing-incidence synchrotron x-ray techniques at the Advanced Photon Source at Argonne National Laboratory. The goals are (1) determine solar wind fluences of the elements Ca-Ge by grazing-incidence angle-resolved x-ray fluorescence (XRF) and x-ray reflectivity, (2) improve data reduction via the development of XRF spectral deconvolution routines and develop modeling algorithms for reflectivity and fluorescence yield analysis in order to determine element specific depth profiles from which absolute concentration may be extracted and (3) designing and developing a new multi-element silicon multi-channel (SMCD) detector system. These improvements will increase our sensitivity by a factor of three or more, reduce measurement time at a given sensitivity to one-eighth and the minimum detection limit would be reduced by a factor of 3 to ∼3 x 10 8 atoms/cm 2 .

  15. ‘Protodesign’: The genesis of design, or a few things that changed the world

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    L Yu Bronzino

    2014-12-01

    Full Text Available The concept ‘design’ that has recently become popular in everyday discourse and among social scientists has not received an unambiguous interpretation. The ambiguity of the concept is due primarily to the complexity of the interpretation of very diverse social practices, the history of which can be traced to the earliest cultural practices of the humankind. This gives the design a universal character and exceptional significance: through the prism of this concept, we can trace the evolution of human culture as a whole. Thus, the study of the concept ‘design’ in the article is based on this theoretical background and emphasizes its basic feature - projectivity genetically related to the project thinking as an essential attribute of human activity. The logic of the article corresponds to the sequence of the main historical stages of the project thinking formation marked by specific inventions. Such an approach allows us to trace the evolution of the design revealing its genesis in the connection with the key moments of the industrial development and scientific and technological revolution as well as the most important social events that contributed to the development of the modern society urban environment and predetermined its social structure.

  16. Geoprospective study of a nuclear waste repository: salt domes; Bibliographic study of their genesis

    International Nuclear Information System (INIS)

    Billaux, D.; Robelin, C.

    1985-01-01

    This report appraises, from the results of a bibliographical study, the possibility of beginning of a domal rise from the salt layer in which or above which would have been placed a repository. The physical mecanisms of salt creep are first screened, together with the factors determining their intensity and relative importance. These factors are primarily the temperature and the state of stress. Semi empirical laws are given for some mecanisms. Present knowledge about the state of the salt in the ground are then examined: we are not able to satisfactorily calculate ''in situ'' stresses, or to explain the existence of an important shear stress, that has been pointed out by most of the stress measurements. The retrospective study of the genesis of existing domes brings an insight into their correlation with sedimentary and tectonic phases. Model studies help us to interpret the distances between domes, and to explain the scale of this phenomenon. After recapitulating the various factors of some importance, we find that the probability of a dome rise from a previously static layer is low, in the time lap we are interested in (100 000 years). Such a rise would have to be triggered by important changes in the sedimentation, erosion or tectonic activity on the site

  17. Genesis and Maintenance of Attentional Biases: The Role of the Locus Coeruleus-Noradrenaline System

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    Mana R. Ehlers

    2017-01-01

    Full Text Available Emotionally arousing events are typically better remembered than mundane ones, in part because emotionally relevant aspects of our environment are prioritized in attention. Such biased attentional tuning is itself the result of associative processes through which we learn affective and motivational relevance of cues. We propose that the locus coeruleus-noradrenaline (LC-NA system plays an important role in the genesis of attentional biases through associative learning processes as well as their maintenance. We further propose that individual differences in and disruptions of the LC-NA system underlie the development of maladaptive biases linked to psychopathology. We provide support for the proposed role of the LC-NA system by first reviewing work on attentional biases in development and its link to psychopathology in relation to alterations and individual differences in NA availability. We focus on pharmacological manipulations to demonstrate the effect of a disrupted system as well as the ADRA2b polymorphism as a tool to investigate naturally occurring differences in NA availability. We next review associative learning processes that—modulated by the LC-NA system—result in such implicit attentional biases. Further, we demonstrate how NA may influence aversive and appetitive conditioning linked to anxiety disorders as well as addiction and depression.

  18. Genesis of Josephitism and functioning the opposition in “anti-Sergius” movement

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    Kamila Pawełczyk-Dura

    2015-11-01

    Full Text Available The crisis in the Russian Orthodox Church, connected with the Patriarch Tikhon’s death, initiated the deep divisions between hierarchs. Deputies of Tikhon, including dignity as a result of the nomination – which was a precedent in the canonical order of the Orthodox Church authorities – were not able to maintain the monolith community, destructed by internal divisions and persecuted by the communist state. Nomination of metropolitan of Nizhny Novogorod on the Guardian of the Patriarchal Throne and publication of The Letter (declaration of the deputy of the Guardian of the Patriarchal Throne Metropolitan Sergius (Stragorodsky of Nizhny Novgorod and the Temporary Saint Synod about the attitude of Russian Orthodox Church to the state authorities underlined differences between the faithful and the clergy. On opposite sides were followers and opponents of the Sergius’ “political line”. Activity of the last ones, manifesting in not-exchanging name of Sergius during liturgy, in moments, when words of the prayer for the superior of the local Church are being said, took the non-institutional forms of movement, definite as not-recalling. This formation, which was essentially the conglomeration of different groups of the clergy and faithful, dominated Josephites – the strongest and most active adherents of the archbishop of Leningrad Joseph (Petrovykh. Genesis those movement as a kind of symbol of opposition to the policy of servility and compromises metropolitan Sergius has been the subject of analysis of this text.

  19. Delayed onset of changes in soma action potential genesis in nociceptive A-beta DRG neurons in vivo in a rat model of osteoarthritis

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    Henry James L

    2009-09-01

    Full Text Available Abstract Background Clinical data on osteoarthritis (OA suggest widespread changes in sensory function that vary during the progression of OA. In previous studies on a surgically-induced animal model of OA we have observed that changes in structure and gene expression follow a variable trajectory over the initial days and weeks. To investigate mechanisms underlying changes in sensory function in this model, the present electrophysiological study compared properties of primary sensory nociceptive neurons at one and two months after model induction with properties in naïve control animals. Pilot data indicated no difference in C- or Aδ-fiber associated neurons and therefore the focus is on Aβ-fiber nociceptive neurons. Results At one month after unilateral derangement of the knee by cutting the anterior cruciate ligament and removing the medial meniscus, the only changes observed in Aβ-fiber dorsal root ganglion (DRG neurons were in nociceptor-like unresponsive neurons bearing a hump on the repolarization phase; these changes consisted of longer half width, reflecting slowed dynamics of AP genesis, a depolarized Vm and an increased AP amplitude. At two months, changes observed were in Aβ-fiber high threshold mechanoreceptors, which exhibited shorter AP duration at base and half width, shorter rise time and fall time, and faster maximum rising rate/maximum falling rate, reflecting accelerated dynamics of AP genesis. Conclusion These data indicate that Aβ nociceptive neurons undergo significant changes that vary in time and occur later than changes in structure and in nociceptive scores in this surgically induced OA model. Thus, if changes in Aβ-fiber nociceptive neurons in this model reflect a role in OA pain, they may relate to mechanisms underlying pain associated with advanced OA.

  20. Climatology of summer midtropospheric perturbations in the US northern plains. Part II: large-scale effects of the Rocky Mountains on genesis

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Shih-Yu. [Iowa State University, Department of Geological and Atmospheric Sciences, Ames, IA (United States); Utah State University, Utah Climate Center, Logan, UT (United States); Chen, Tsing-Chang [Iowa State University, Department of Geological and Atmospheric Sciences, Ames, IA (United States); Takle, Eugene S. [Iowa State University, Department of Geological and Atmospheric Sciences, Ames, IA (United States); Iowa State University, Department of Agronomy, Ames, IA (United States)

    2011-04-15

    Propagating convective storms across the US northern plains are often coupled with preexisting midtropospheric perturbations (MPs) initiated over the Rocky Mountains. A companion study (Part I) notes that such MPs occur most commonly at 12 UTC (early morning) and 00 UTC (late afternoon). Using a regional reanalysis and a general circulation model (GCM), this study investigates how such a bimodal distribution of the MP frequency is formed. The results point to two possible mechanisms working together while each has a different timing in terms of maximum effect. The diurnal evolutions between the midtropospheric flows over the Rockies and over the Great Plains are nearly out-of-phase due to inertial oscillation. During the nighttime, the westerly flows at 700-500 mb over the Rockies intensify while flows at the same level over the Great Plains turn easterly. These two flows converge over the eastern Rockies and induce cyclonic vorticity through vortex stretching. After sunrise, the convergence dissipates and the cyclonic vorticity is redistributed by horizontal vorticity advection, moving it downstream. This process creates a climatological zonally propagating vorticity signal which, in turn, facilitates the early-morning MP genesis at 12 UTC. The analysis also reveals marked dynamic instability conducive to subsynoptic-scale disturbances in the midtroposphere over the Rockies. Strong meridional temperature gradients appear over the north-facing slopes of the Rockies due to terrain heating to the south and the presence of cooler air to the north. This feature, along with persistent vertical shear, creates a Charney-Stern type of instability (i.e. sign changes of the meridional potential vorticity gradient). Meanwhile, the development of terrain boundary layer reduces the Rossby deformation radius which, subsequently, enhances the likelihood for baroclinic short waves. Such effects are most pronounced in the late afternoon and therefore are supportive to the MP

  1. Genesis Contingency Planning and Mishap Recovery: The Sample Curation View

    Science.gov (United States)

    Stansbery, E. K.; Allton, J. H.; Allen, C. C.; McNamara, K. M.; Calaway, M.; Rodriques, M. C.

    2007-01-01

    Planning for sample preservation and curation was part of mission design from the beginning. One of the scientific objectives for Genesis included collecting samples of three regimes of the solar wind in addition to collecting bulk solar wind during the mission. Collectors were fabricated in different thicknesses for each regime of the solar wind and attached to separate frames exposed to the solar wind during specific periods of solar activity associated with each regime. The original plan to determine the solar regime sampled for specific collectors was to identify to which frame the collector was attached. However, the collectors were dislodged during the hard landing making identification by frame attachment impossible. Because regimes were also identified by thickness of the collector, the regime sampled is identified by measuring fragment thickness. A variety of collector materials and thin films applied to substrates were selected and qualified for flight. This diversity provided elemental measurement in more than one material, mitigating effects of diffusion rates and/or radiation damage. It also mitigated against different material and substrate strengths resulting in differing effects of the hard landing. For example, silicon crystal substrates broke into smaller fragments than sapphire-based substrates and diamond surfaces were more resilient to flying debris damage than gold. The primary responsibility of the curation team for recovery was process documentation. Contingency planning for the recovery phase expanded this responsibility to include not only equipment to document, but also gather, contain and identify samples from the landing area and the recovered spacecraft. The team developed contingency plans for various scenarios as part of mission planning that included topographic maps to aid in site recovery and identification of different modes of transport and purge capability depending on damage. A clean tent, set-up at Utah Test & Training Range

  2. The study of major, trace and rare earth elements geochemistry in Shahrestanak Mn deposit, south of Qom: Implications for genesis

    Directory of Open Access Journals (Sweden)

    Mohammad Maanijou

    2015-04-01

    Full Text Available Introduction The Shahrestanak Mn deposit is located in southern Qom province, 12 km southwest of the city of Kahak. Based on geological-structural divisions of Iran, the deposit belongs to central volcanic belt or Urumieh-Dokhtar zone. The Venarch deposit is one the most important known manganese deposits in Iran. The Sharestanak and Venarch deposits are spatially and temporally related to each other, and have similar geology, mineral texture and structure, host rocks, relationships with faults, and depositional environment. So, their magmatism and deposition conditions can be related to each other. Since no systematic study on the Shahrestanak deposit had been performed before discussing its geological and geochemical characteristics, here it is being attempted to study the geology, petrography, geochemistry of major, minor and trace elements, and Rare Earth Elements (REE of ore, to distinguish the depositional environments and genesis of this deposit and to compare REE of ore in this deposit with other deposits. Sampling and method of study Fourteen samples of manganese ore were selected for geochemical study and analyzing of major, minor, trace elements and REE by ICP-AES and ICP-MS and were sent to SGS Co., Toronto. Detection limits for major elements and trace elements are 0.01% and 0.05ppm, respectively. Result and discussion The deposit is characterized by various lithology and stratigraphy units, consist of: 1 Middle to -Upper Eocene volcano-sedimentary rocks, 2 Oligocene lower red conglomerate and sandstone, 3 Oligo-Miocene limestone and marl (Qom Formation, and 4 Eocene and Lower Miocene basic to intermediate dykes. The most abundant minerals of the deposit are braunite, hausmannite, pyrolusite, and manganite. Evidences such as high Mn/Fe (11.33 and Si/Al (4.86 ratios, low contents of trace elements specially Co (11.40 ppm, Ni (24 ppm, Cu (81.85 ppm, and Ce, with high amounts of SiO2, Mn, Fe, Ba, Zn, As and Sr, all represent

  3. Factors associated with television viewing time in toddlers and preschoolers in Greece: the GENESIS study.

    Science.gov (United States)

    Kourlaba, Georgia; Kondaki, Katerina; Liarigkovinos, Thodoris; Manios, Yannis

    2009-06-01

    The aim of this work was to describe the television (TV) viewing time of preschoolers and to examine factors that may be associated with it. A representative sample of 2374 Greek children aged 1-5 years was examined (GENESIS study). Several anthropometric, socio-demographic and lifestyle characteristics were recorded. The mean value of children's TV viewing time was 1.32 h/day. Twenty six percent of participants spent > or =2 h/day in TV viewing. The percentage of children whose TV viewing time was longer than 2 h/day was higher in children aged 3-5 years (32.2%) than in those aged 1-2 years (11.1%). Multiple logistic regression revealed that the time parents spent viewing TV and the region of residence were significantly associated with child's TV viewing time among children aged 3-5 years. Among children aged 1-2 years, the maternal educational status, the region of residence and the maternal TV viewing time were found to be related to child's TV viewing time. The current findings suggest that almost one third of Greek preschoolers exceed the limit of 2 h/day TV viewing and that parental TV viewing time may be the most important determinant of children's TV viewing time.

  4. The genesis, stratigraphy and age of Finnish peat deposits. Soiden syntvy, rakenne ja ikae Suomessa

    Energy Technology Data Exchange (ETDEWEB)

    Glueckert, G [Turun yliopisto (Finland). Maaperaegeologian osasto

    1986-01-01

    The genesis, stratigraphy and age of Finnish peat deposits are briefly described. Finnish peats are classified according to their botanical composition to Sphagnum, sedge (Carex) and wood peats. They form complex types of peat land: the ombrotrophic raised bogs in southern Finland and the minerotrophic open sedge (aapa) bogs in northern Finland. The structural bog types in the geological classification are mainly composed of Sphagnum and Carex peats. The raised bogs are predominantly built up of Sphagnum peat, the aapa bogs of Carex peat. The bogs are formed by paludification of lakes, of rising coasts or of low-lying forests. The thickness of peat varies from 3 to 8 m in southern Finland and from 1 to 3 m in northern Finland. The age of the bogs varies according to the uplift of land and the altitude of the bog gasin above sea level. The oldest bogs are 9500-10000 years old and formed in southern and eastern Finland on high-lying upland tracts just after the retreat of the ice at the end of the last glaciation. The geological and palaeontological development of bogs and the history of climate and vegetation can be studied and dated pollenanalytically and with the radiocarbon method.

  5. Role of anxiety and depressive disorders in the genesis of psychosomatic disorders

    Directory of Open Access Journals (Sweden)

    Aleksandr Anatolyevich Shatenshtein

    2013-01-01

    Full Text Available Patients and methods. The results of clinical and psychodiagnostic examination using the Minnesota Multiphasic Personality Inventory (MMPI were analyzed in 210 therapeutic inpatients from 4 groups of psychosomatic diseases (coronary heart disease, hypertensive disease, duodenal ulcer disease, asthma, and bronchitis with an asthmatic component and 3 groups of diseases in whose genesis the psychosomatic mechanisms (pneumonia, gastritis, renal diseases played a lesser role. Healthy individuals (n=38 served as a control group. The correlation coefficients between the first scale reflecting the number of somatic complaints and the magnitude of their hypochondriacal fixation and the second one characterizing the degree of anxiety and depressive disorders were calculated within each disease group. Results. In psychosomatic diseases, the correlation coefficients between the first and second MMPI scales proved to be insignificant and substantially lower than those in the healthy individuals. This suggests that in such patients, a larger number of somatic complaints and their enhanced hypochondriacal fixation alleviate anxiety and depressive disorders, which may be regarded as an indication that there is psychosomatic defense that lessens anxiety due to a somatic disease. In somatic diseases that are not referring to as psychosomatic ones, the correlation coefficient between the first and second scales is highly significant and considerably higher than that in the healthy individuals and particularly higher than in the group of psychosomatic diseases. In the patients of these groups, an increase in anxiety and depression aggravates autonomic dysregulation reflecting in the larger number of hypochondriacal complaints. This direct relationship between autonomic functions and the level of anxiety and depression may be a risk factor for developing these disorders.

  6. 浙江省观赏石成因和分布规律%Distribution, Genesis and Regional Geological Background of View Stones in Zhejiang Province

    Institute of Scientific and Technical Information of China (English)

    陈美君; 王杜涛; 王加恩

    2012-01-01

    By the research and evaluation on the view stones in Zhejiang, it proves that there are plenty of various resources of view stones; 30 types and 63 localities of view stones have been found. Now the paper describes the main several stones' distribution and genesis in detail, especially researches from the regional geological background.%浙江省内观赏石资源丰富、类型齐全,目前已查明观赏石产地63处。本文初步探讨了浙江观赏石成因和分布规律。

  7. The genesis of the AIDS policy and AIDS Space in Brazil (1981-1989)

    Science.gov (United States)

    de Barros, Sandra Garrido; Vieira-da-Silva, Ligia Maria

    2016-01-01

    ABSTRACT OBJECTIVE To analyze the genesis of the policy for controlling AIDS in Brazil. METHODS Socio-historical study (1981-1989), based on Bordieu’s genetic sociology, by document analysis, bibliographical review, and in-depth interviews. It consisted of a connection between the analysis of the paths of 33 agents involved in the creation of a social space focusing on AIDS-related issues and the historical possibility conditions of the drafting of a specific policy. RESULTS AIDS Space is a gathering point for the paths of agents from several social fields (medical, scientific, political, and bureaucratic fields). A specific space for relationships, which enabled the drafting of a policy for controlling the AIDS epidemic, but also a place where the authority to talk about the meaning of the disease, the methods to prevent and treat it was under dispute. The analysis showed how the various structures (democratic administrations in Sao Paulo and at the national level, with public health officers taking important positions) and the lack of a specific therapy contributed to social agents of different ranks and backgrounds to initially set prevention as a priority. CONCLUSIONS The rise of the sanitary movement, the organization of SUS, and the dominance of the medical field at the AIDS Space contributed to foster treatment as a part of the measures to control the epidemic. These conditions allowed drafting a policy based on the integrality of care, by linking prevention and treatment in the following decade, with important participation from state bureaucracy and researchers. PMID:27463255

  8. Genesis of textural contrasts in subsurface soil horizons in the Northern Pantanal-Brazil

    Directory of Open Access Journals (Sweden)

    Alexandre Ferreira do Nascimento

    2013-10-01

    Full Text Available The Pantanal region can be characterized as a quaternary floodplain with predominant sedimentation in the form of alluvial fans. In the geomorphologic and sedimentary evolution, the avulsion process is inherent to this depositional system and its dynamics, together with surface water floods, influence soil sedimentation on this plain. The knowledge and differentiation of these two events can contribute to a better understanding of the variability of soil properties and distribution under the influence of these sedimentation processes. Therefore, this study investigated the genesis of soils in the Northern Pantanal with textural contrasts in deeper horizons and their relationship with the depositional system dynamics. We analyzed four soil profiles in the region of Barão de Melgaço, Mato Grosso State, Brazil (RPPN SESC Pantanal. Two profiles were sampled near the Rio Cuiabá (AP1 and AP4 and two near the Rio São Lourenço (AP10 and AP11. In AP11, the horizons contrast in particle size between the profile basis and the surface. In AP1, AP4 and AP10, the horizons overlaying the sand layer have similar particle size properties, mainly in terms of sand distribution. In the first case, floods (surface water seem to have originated the horizons and layers with contrasting texture. In the second case, avulsion is the most pronounced process. Therefore, the two modes can form soils with contrasting texture that are discriminable by soil morphology, based on the distinct features associated to the specific sedimentation processes.

  9. The genesis of the AIDS policy and AIDS Space in Brazil (1981-1989

    Directory of Open Access Journals (Sweden)

    Sandra Garrido de Barros

    2016-01-01

    Full Text Available ABSTRACT OBJECTIVE To analyze the genesis of the policy for controlling AIDS in Brazil. METHODS Socio-historical study (1981-1989, based on Bordieu’s genetic sociology, by document analysis, bibliographical review, and in-depth interviews. It consisted of a connection between the analysis of the paths of 33 agents involved in the creation of a social space focusing on AIDS-related issues and the historical possibility conditions of the drafting of a specific policy. RESULTS AIDS Space is a gathering point for the paths of agents from several social fields (medical, scientific, political, and bureaucratic fields. A specific space for relationships, which enabled the drafting of a policy for controlling the AIDS epidemic, but also a place where the authority to talk about the meaning of the disease, the methods to prevent and treat it was under dispute. The analysis showed how the various structures (democratic administrations in Sao Paulo and at the national level, with public health officers taking important positions and the lack of a specific therapy contributed to social agents of different ranks and backgrounds to initially set prevention as a priority. CONCLUSIONS The rise of the sanitary movement, the organization of SUS, and the dominance of the medical field at the AIDS Space contributed to foster treatment as a part of the measures to control the epidemic. These conditions allowed drafting a policy based on the integrality of care, by linking prevention and treatment in the following decade, with important participation from state bureaucracy and researchers.

  10. The neural stem cell fate determinant TLX promotes tumorigenesis and genesis of cells resembling glioma stem cells.

    Science.gov (United States)

    Park, Hyo-Jung; Kim, Jun-Kyum; Jeon, Hye-Min; Oh, Se-Yeong; Kim, Sung-Hak; Nam, Do-Hyun; Kim, Hyunggee

    2010-11-01

    A growing body of evidence indicates that deregulation of stem cell fate determinants is a hallmark of many types of malignancies. The neural stem cell fate determinant TLX plays a pivotal role in neurogenesis in the adult brain by maintaining neural stem cells. Here, we report a tumorigenic role of TLX in brain tumor initiation and progression. Increased TLX expression was observed in a number of glioma cells and glioma stem cells, and correlated with poor survival of patients with gliomas. Ectopic expression of TLX in the U87MG glioma cell line and Ink4a/Arf-deficient mouse astrocytes (Ink4a/Arf(-/-) astrocytes) induced cell proliferation with a concomitant increase in cyclin D expression, and accelerated foci formation in soft agar and tumor formation in in vivo transplantation assays. Furthermore, overexpression of TLX in Ink4a/Arf(-/-) astrocytes inhibited cell migration and invasion and promoted neurosphere formation and Nestin expression, which are hallmark characteristics of glioma stem cells, under stem cell culture conditions. Our results indicate that TLX is involved in glioma stem cell genesis and represents a potential therapeutic target for this type of malignancy.

  11. Genesis of the North German basin - a metamorphosis model; Die Entstehung des Norddeutschen Beckens - ein Metamorphose-Modell

    Energy Technology Data Exchange (ETDEWEB)

    Brink, H.J. [ExxonMobil Production Deutschland GmbH, Hannover (Germany)

    2003-07-01

    In an integrative analysis, metamorphosis processes in the aggregated crust, potential field anomalies, the temperature field and the subsidence history are combined into a model of the genesis of the North German Basin. The model takes account of phenomena like high nitrogen concentrations in natural gases of permian sandstone and the structure of the crust and combines them with theoretical considerations. The new model for explaining geonsynclinals, in which geochemical and petrophysical processes in the lower crust have a decisive role, appears to be globally applicable. It can provide an intrinsic variant of the application of existing tectonic expansion models for explaining the subsidence of sediment basins. [German] In einer integrativen Analyse werden Metamorphoseprozesse in der aggregierten Kruste, Potentialfeldanomalien, Temperaturfeld sowie die Subsidenzgeschichte zu einem Modell fuer die Entstehung des Norddeutschen Beckens zusammengefasst, das beobachtete Phaenomene wie Stickstoffreichtum in Erdgasen permischer Sandsteine und die Struktur der Kruste mit theoretischen Ableitungen verknuepft. Das so entstandene neue Modell zur Erklaerung von Geosynklinalen, bei dem geochemisch/petrophysikalische Prozesse in der Unterkruste eine entscheidende Rolle spielen, scheint global anwendbar zu sein. Es kann die Anwendung existierender tektonischer Dehnungsmodelle zur Erklaerung der Subsidenz von Sedimentbecken um eine intrinsische Variante ergaenzen. (orig.)

  12. Magma genesis at Gale Crater: Evidence for Pervasive Mantle Metasomatism

    Science.gov (United States)

    Filiberto, J.

    2017-12-01

    Basaltic rocks have been analyzed at Gale Crater with a larger range in bulk chemistry than at any other landing site [1]. Therefore, the rocks may have experienced significantly different formation conditions than those experienced by magmas at Gusev Crater or Meridiani Planum. Specifically, the rocks at Gale Crater have higher potassium than other Martian rocks, with a potential analog of the Nakhlite parental magma, and are consistent with forming from a metasomatized mantle source [2-4]. Mantle metasomatism would not only affect the bulk chemistry but mantle melting conditions, as metasomatism fluxes fluids into the source region. Here I will combine differences in bulk chemistry between Martian basalts to calculate formation conditions in the interior and investigate if the rocks at Gale Crater experienced magma genesis conditions consistent with metasomatism - lower temperatures and pressures of formation. To calculate average formation conditions, I rely on experimental results, where available, and silica-activity and Mg-exchange thermometry calculations for all other compositions following [5, 6]. The results show that there is a direct correlation between the calculated mantle potential temperature and the K/Ti ratio of Gale Crater rocks. This is consistent with fluid fluxed metasomatism introducing fluids to the system, which depressed the melting temperature and fluxed K but not Ti to the system. Therefore, all basalts at Gale Crater are consistent with forming from a metasomatized mantle source, which affected not only the chemistry of the basalts but also the formation conditions. References: [1] Cousin A. et al. (2017) Icarus. 288: 265-283. [2] Treiman A.H. et al. (2016) Journal of Geophysical Research: Planets. 121: 75-106. [3] Treiman A.H. and Medard E. (2016) Geological Society of America Abstracts with Programs. 48: doi: 10.1130/abs/2016AM-285851. [4] Schmidt M.E. et al. (2016) Geological Society of America Abstracts with Programs. 48: doi: 10

  13. A numerical study of the role of the vertical structure of vorticity during tropical cyclone genesis

    International Nuclear Information System (INIS)

    Venkatesh, T N; Mathew, Joseph

    2010-01-01

    An eight-level axisymmetric model with simple parameterizations for clouds and the atmospheric boundary layer was developed to examine the evolution of vortices that are precursors to tropical cyclones. The effect of vertical distributions of vorticity, especially that arising from a merger of mid-level vortices, was studied by us to provide support for a new vortex-merger theory of tropical cyclone genesis. The basic model was validated with the analytical results available for the spin-down of axisymmetric vortices. With the inclusion of the cloud and boundary layer parameterizations, the evolution of deep vortices into hurricanes and the subsequent decay are simulated quite well. The effects of several parameters such as the initial vortex strength, radius of maximum winds, sea-surface temperature and latitude (Coriolis parameter) on the evolution were examined. A new finding is the manner in which mid-level vortices of the same strength decay and how, on simulated merger of these mid-level vortices, the resulting vortex amplifies to hurricane strength in a realistic time frame. The importance of sea-surface temperature on the evolution of full vortices was studied and explained. Also it was found that the strength of the surface vortex determines the time taken by the deep vortex to amplify to hurricane strength.

  14. Genesis Solar Wind Science Canister Components Curated as Potential Solar Wind Collectors and Reference Contamination Sources

    Science.gov (United States)

    Allton, J. H.; Gonzalez, C. P.; Allums, K. K.

    2016-01-01

    The Genesis mission collected solar wind for 27 months at Earth-Sun L1 on both passive and active collectors carried inside of a Science Canister, which was cleaned and assembled in an ISO Class 4 cleanroom prior to launch. The primary passive collectors, 271 individual hexagons and 30 half-hexagons of semiconductor materials, are described in. Since the hard landing reduced the 301 passive collectors to many thousand smaller fragments, characterization and posting in the online catalog remains a work in progress, with about 19% of the total area characterized to date. Other passive collectors, surfaces of opportunity, have been added to the online catalog. For species needing to be concentrated for precise measurement (e.g. oxygen and nitrogen isotopes) an energy-independent parabolic ion mirror focused ions onto a 6.2 cm diameter target. The target materials, as recovered after landing, are described in. The online catalog of these solar wind collectors, a work in progress, can be found at: http://curator.jsc.nasa.gov/gencatalog/index.cfm This paper describes the next step, the cataloging of pieces of the Science Canister, which were surfaces exposed to the solar wind or component materials adjacent to solar wind collectors which may have contributed contamination.

  15. Composition, characteristics and genesis of the ferromanganese crusts and nodules from the Indian and Pacific oceans

    Science.gov (United States)

    Chen, S.; Peng, X.

    2017-12-01

    Ferromanganese crusts and nodules are considered to be one of the most important players in the geochemical cycling of the oceans. However, the lack of integrated studies affects our explicit understanding of the mineralization, characteristics and genesis of the crusts and nodules. In this study, the mineralogy, geochemistry and molecular biology in ferromanganese crusts and nodules obtained from various oceans were explored. The crusts/nodules are composed predominantly of vernadite (δ-MnO2) and amorphous Fe oxides/hydroxides. The shale normalized negative Ce-anomalies, characteristic of hydrothermal oxides, are retained in JL and TVG6. In hydrogenous oxides, the positive Ce-anomalies were found in 21V-S7 and DY119-4. The iron isotopic compositions range between -0.543 and -0.002‰ in δ56Fe IRMM14. Using molecular 16S rRNA gene techniques (clone libraries, real-time PCR) we show that nodules (JL-B and TVG6) provide a suitable habitat for prokaryotes with an abundant and diverse prokaryotic community dominated by Mn(II)-oxidizing bacteria (Pseudomonas putida GB-1). These bacteria were not detected in the crust samples (21V-S7 and DY119-4). The results suggest that a biologically driven Manganese cycle inside the nodule that may be relevant to their formation.

  16. WATER RESOURCES IN THE ROMANIAN CARPATHIANS – GENESIS, TERRITORIAL DISTRIBUTION, MANAGEMENT

    Directory of Open Access Journals (Sweden)

    P. GÂȘTESCU

    2014-05-01

    Full Text Available Water resources in Romanian Carpathians-genesis, territorial distribution, management. Discussing water resources in Romania implies a twofold approach: water as a sine qua non of life itself and water as an important factor for the development of the contemporary society. Lying in a temperate zone, Romania’s water resources are rather modest compared with other countries in Europe. Inland rivers span 78,905 km (referred only to the 4,864 codified watercourses at an average density: 0.38 km/km2 and an annual volume: 40.6 billion m3, which means 1,765 m3/capita. To knowledge ground waters are put at 9.62 billion m3/year, of which 6 billion can be used in optimal technological and economic conditions. According to a recent UN statistical report, Romania lists at position 21 among the 34 European. Natural lakes are replenished from precipitation and springs water every year and the reserves are estimated at around 1 billion m3/year and are of local importance for water management schemes. The Black Sea (in the Romanian sector could become a major source if sea water desalting could be economical.The water resources of the drainage network were calculated on the basis of the mean liquid flow map (scale 1: 500,000 releves picture of river-water resources in the major relief units: the Carpathian, which occupies only 27.9% of the Romanian territory, 65.3% (26.48 billion mc from a total of 40.61 billion m3 of the water is formed and regenerated every year; the hill unit, which includes the Subcarpathians, the tablelands and the piedmont hills, and occupies 42.4% of Romania’s territory, only 28.0% of the water volume is formed (11.38 billion m3, of which 8.7% (3.51 billion m3 in the Subcarpathians and 19.4% (7.87 billion m3 in the other two units; the plain unit, which covers 29.7% of the country’s territory, the water volume formed there is small (6.7%

  17. ["Directed perception", "mood", "social reinforcement". Sketches towards the historical semantics of Ludwik Fleck's Genesis and Development of a Scientific Fact].

    Science.gov (United States)

    Bauer, Julian

    2014-01-01

    This article analyses three basic concepts of Ludwik Fleck's Genesis and Development of a Scientific Fact. It shows first that Fleck's notion of "directed perception" is closely linked to Jakob von Uexküll's writings on the "Umwelt" of animals and humans. The article then proposes to regard the epistemological debates surrounding parapsychology as an important testing ground for the Fleckian concept of „mood“ and his concomitant hypotheses about „the tenacity of systems of opinion and the harmony of illusions". It finally argues that Fleck's modification of Wilhelm Jerusalem's idea of the "social consolidation" of knowledge helps us to understand the indebtedness of Fleck towards early functionalist sociology as well as his strong belief in "specific historical laws governing the development of ideas"The historical semantics of Fleck's works hence proves that his insights are neither marginal nor revolutionary but rather deeply rooted within scientific traditions from the late 19th and early 20th centuries.

  18. In vivo tissue engineering: Part I. Concept genesis and guidelines for its realization.

    Science.gov (United States)

    Zdrahala, R J; Zdrahala, I J

    1999-10-01

    A loss of function of an organ often represents a life-threatening situation. Transplantations are successful, but "replacement" availability, its compatibility with the host, and subsequent healing often pose serious questions. Tissue engineering, where a carefully prepared scaffold is populated, in vitro, by cells to form an artificial organ, addresses some of the problems mentioned above. Trauma associated with the implant introduction to the host often complicates the process. The novel concept of in vivo tissue engineering which is designed to mediate the healing and tissue regeneration process by providing an in vitro formed porous, microcellular scaffold is proposed. The scaffold (part or entire organ) is then populated by cells either spontaneously (the surrounding cells will spread and populate to inhabit the scaffold) or by cellular augmentation (encapsulated cells are delivered to this in statu nascendi scaffold). Minimally traumatic arthroscopic surgery combined with a unique polymer delivery system is envisioned for the introduction of this implant to a site to be repaired. Such an approach will require the formation of polymer in-situ, in a reasonable time. The scaffold-forming polymers will be, in principle, biodegradable. We propose to utilize biodegradable polyurethane systems for in vivo tissue engineering. Diversity of their structure/property relationships, relative "ease" of their preparation, and excellent biocompatibility predetermine polyurethanes to be the materials of choice. This paper describes the genesis of this concept and potentials for its realization. It is intended to initiate and stimulate discussion among the related scientific disciplines to form a basis for this field. The synthesis, application, and biodegradation of selected polyurethanes and variety of its medical utilization will be discussed in upcoming papers.

  19. Vanadium-rich ruby and sapphire within Mogok Gemfield, Myanmar: implications for gem color and genesis

    Science.gov (United States)

    Zaw, Khin; Sutherland, Lin; Yui, Tzen-Fu; Meffre, Sebastien; Thu, Kyaw

    2015-01-01

    Rubies and sapphires are of both scientific and commercial interest. These gemstones are corundum colored by transition elements within the alumina crystal lattice: Cr3+ yields red in ruby and Fe2+, Fe3+, and Ti4+ ionic interactions color sapphires. A minor ion, V3+ induces slate to purple colors and color change in some sapphires, but its role in coloring rubies remains enigmatic. Trace element and oxygen isotope composition provide genetic signatures for natural corundum and assist geographic typing. Here, we show that V can dominate chromophore contents in Mogok ruby suites. This raises implications for their color quality, enhancement treatments, geographic origin, exploration and exploitation and their comparison with rubies elsewhere. Precise LA-ICP-MS analysis of ruby and sapphire from Mogok placer and in situ deposits reveal that V can exceed 5,000 ppm, giving V/Cr, V/Fe and V/Ti ratios up to 26, 78, and 97 respectively. Such values significantly exceed those found elsewhere suggesting a localized geological control on V-rich ruby distribution. Our results demonstrate that detailed geochemical studies of ruby suites reveal that V is a potential ruby tracer, encourage comparisons of V/Cr-variation between ruby suites and widen the scope for geographic typing and genesis of ruby. This will allow more precise comparison of Asian and other ruby fields and assist confirmation of Mogok sources for rubies in historical and contemporary gems and jewelry.

  20. Changes of Retina Are Not Involved in the Genesis of Visual Hallucinations in Parkinson’s Disease

    Directory of Open Access Journals (Sweden)

    Aleš Kopal

    2015-01-01

    Full Text Available Parkinson’s disease (PD is characterized by motor and nonmotor symptoms. Nonmotor symptoms include primarily visual hallucinations (VH. The aim of our study was to establish whether patients with PD and visual hallucinations (PDH+ have structural changes of retina detected by an optical coherence tomography (OCT in comparison with PD patients without visual hallucinations (PDH−. We examined 52 PD patients (18 with VH, 34 without VH and 15 age and sex matched healthy controls. Retinal nerve fiber layer (RNFL thickness and macular thickness and volume were assessed by OCT. Functional impairment of retina was assessed using 2.5% contrast sensitivity test. For OCT outcomes we analyzed 15 PDH+ and 15 PDH− subjects matched for age, gender, and PD duration. For contrast sensitivity we analyzed 8 pairs of patients matched for age, gender, and visual acuity. There was no significant difference in RNFL thickness and macular thickness and macular volume between 15 PDH+ and 15 PDH− subjects, and also between a group of 44 PD patients (both PDH+ and PDH− and 15 age and gender matched healthy controls. No significant difference was found for 2.5% contrast sensitivity test values between PDH+ and PDH− subjects. Therefore we conclude that functional and structural changes in retina play no role in genesis of VH in PD.

  1. Clinical study on role of life events in genesis of neurotic disorders and depression

    Directory of Open Access Journals (Sweden)

    Deepanjali Medhi

    2015-07-01

    Full Text Available Background: This study was conducted to know about the role of life events in genesis of neurotic disorders and depression in four groups of patients with dissociative disorder, somatisation disorder, generalized anxiety disorder (GAD, and depression. It was conducted in the Department of Psychiatry, Gauhati Medical College and Hospital, Guwahati, Assam, India. Methods and materials: It was a case control study with 100 cases of neurotic disorders and depression (25 cases in each group attending indoor and outdoor, and diagnosed using research diagnostic criteria of the tenth revision of the International Statistical Classification of Diseases and Related Health Problems (ICD-10. The groups were compared with similar number of matched controls, in respect to number, scoring, and type of life events occurring within one year prior to the onset of illness using the Presumptive Stressful Life Events Scale (PSLES. Variables related to socio-demographic characteristics were also seen between cases and controls. Result and conclusion: Number of life events was significantly higher in depressive and generalized anxiety groups than control group. Total life events scores were significantly higher in depressive and generalized anxiety group than control group. Undesirable events were significantly higher in all groups. Personal events were significantly higher in depressives than control. Events related to interpersonal relation were significantly higher in depressive, dissociative, and GAD groups than control. Bereavement was closely associated with depression and GAD. Events related to health, finance, and education were higher in dissociative group than control. Events related to move were found significantly higher in GAD group than control. Implications of the findings are discussed.

  2. Genesis of mammalian prions: from non-infectious amyloid fibrils to a transmissible prion disease.

    Directory of Open Access Journals (Sweden)

    Natallia Makarava

    2011-12-01

    Full Text Available The transmissible agent of prion disease consists of a prion protein in its abnormal, β-sheet rich state (PrP(Sc, which is capable of replicating itself according to the template-assisted mechanism. This mechanism postulates that the folding pattern of a newly recruited polypeptide chain accurately reproduces that of a PrP(Sc template. Here we report that authentic PrP(Sc and transmissible prion disease can be generated de novo in wild type animals by recombinant PrP (rPrP amyloid fibrils, which are structurally different from PrP(Sc and lack any detectable PrP(Sc particles. When induced by rPrP fibrils, a long silent stage that involved two serial passages preceded development of the clinical disease. Once emerged, the prion disease was characterized by unique clinical, neuropathological, and biochemical features. The long silent stage to the disease was accompanied by significant transformation in neuropathological properties and biochemical features of the proteinase K-resistant PrP material (PrPres before authentic PrP(Sc evolved. The current work illustrates that transmissible prion diseases can be induced by PrP structures different from that of authentic PrP(Sc and suggests that a new mechanism different from the classical templating exists. This new mechanism designated as "deformed templating" postulates that a change in the PrP folding pattern from the one present in rPrP fibrils to an alternative specific for PrP(Sc can occur. The current work provides important new insight into the mechanisms underlying genesis of the transmissible protein states and has numerous implications for understanding the etiology of neurodegenerative diseases.

  3. Phylogenetic detection of horizontal gene transfer during the step-wise genesis of Mycobacterium tuberculosis

    Directory of Open Access Journals (Sweden)

    Turenne Christine

    2009-08-01

    Full Text Available Abstract Background In the past decade, the availability of complete genome sequence data has greatly facilitated comparative genomic research aimed at addressing genetic variability within species. More recently, analysis across species has become feasible, especially in genera where genome sequencing projects of multiple species have been initiated. To understand the genesis of the pathogen Mycobacterium tuberculosis within a genus where the majority of species are harmless environmental organisms, we have used genome sequence data from 16 mycobacteria to look for evidence of horizontal gene transfer (HGT associated with the emergence of pathogenesis. First, using multi-locus sequence analysis (MLSA of 20 housekeeping genes across these species, we derived a phylogeny that serves as the basis for HGT assignments. Next, we performed alignment searches for the 3989 proteins of M. tuberculosis H37Rv against 15 other mycobacterial genomes, generating a matrix of 59835 comparisons, to look for genetic elements that were uniquely found in M. tuberculosis and closely-related pathogenic mycobacteria. To assign when foreign genes were likely acquired, we designed a bioinformatic program called mycoHIT (mycobacterial homologue investigation tool to analyze these data in conjunction with the MLSA-based phylogeny. Results The bioinformatic screen predicted that 137 genes had been acquired by HGT at different phylogenetic strata; these included genes coding for metabolic functions and modification of mycobacterial lipids. For the majority of these genes, corroborating evidence of HGT was obtained, such as presence of phage or plasmid, and an aberrant GC%. Conclusion M. tuberculosis emerged through vertical inheritance along with the step-wise addition of genes acquired via HGT events, a process that may more generally describe the evolution of other pathogens.

  4. Automated calibration of TECAN genesis liquid handling workstation utilizing an online balance and density meter.

    Science.gov (United States)

    Xie, Iris H; Wang, Michael H; Carpenter, Richard; Wu, Henry Y

    2004-02-01

    With robotics widely used in bioanalytical assays, accurate system performance is essential to ensure the quality and productivity of the robotics. In our lab, an automated calibration procedure has been developed to evaluate the precision and accuracy of the TECAN (Research Triangle Park, NC, U.S.A.) Genesis liquid handling system in a bioanalytical laboratory setting. The calibrations were performed by transferring and weighing the solvents automatically on a microbalance controlled by a Gemini program. From the data acquired, calibration reports were generated using a template. The novel aspect of this approach is the use of an on-line balance and a density meter, both of which combine to make the calibration process simple, efficient, and precise. For quantitative bioanalysis, a variety of solvents, including methanol, water, mixed solvents, and plasma, are typically used to prepare standards and unknown samples. Density information is usually unknown for the mixed solvents, and the density of plasma can vary from species to species. However, with the use of a universal density meter, the density could be obtained in seconds. The issue of solvent evaporation during the calibration process was also addressed. Calibration curves were set up for various liquid classes. Pipetting volumes ranged from 10 microL to 900 microL. Precision and accuracy results obtained from the semiannual performance evaluations showed this procedure to be reliable and user-friendly. Using the automated calibration procedure, the calibration and performance evaluation of the robotic system is considerably more efficient, and the incidence of unacceptable precision and accuracy is greatly reduced.

  5. Elucidating the phenomenon of HESC-derived RPE: anatomy of cell genesis, expansion and retinal transplantation.

    Science.gov (United States)

    Vugler, Anthony; Carr, Amanda-Jayne; Lawrence, Jean; Chen, Li Li; Burrell, Kelly; Wright, Andrew; Lundh, Peter; Semo, Ma'ayan; Ahmado, Ahmad; Gias, Carlos; da Cruz, Lyndon; Moore, Harry; Andrews, Peter; Walsh, James; Coffey, Peter

    2008-12-01

    Healthy Retinal Pigment Epithelium (RPE) cells are required for proper visual function and the phenomenon of RPE derivation from Human Embryonic Stem Cells (HESC) holds great potential for the treatment of retinal diseases. However, little is known about formation, expansion and expression profile of RPE-like cells derived from HESC (HESC-RPE). By studying the genesis of pigmented foci we identified OTX1/2-positive cell types as potential HESC-RPE precursors. When pigmented foci were excised from culture, HESC-RPE expanded to form extensive monolayers, with pigmented cells at the leading edge assuming a precursor role: de-pigmenting, proliferating, expressing keratin 8 and subsequently re-differentiating. As they expanded and differentiated in vitro, HESC-RPE expressed markers of both developing and mature RPE cells which included OTX1/2, Pax6, PMEL17 and at low levels, RPE65. In vitro, without signals from a developing retinal environment, HESC-RPE could produce regular, polarised monolayers with developmentally important apical and basal features. Following transplantation of HESC-RPE into the degenerating retinal environment of Royal College of Surgeons (RCS) dystrophic rats, the cells survived in the subretinal space, where they maintained low levels of RPE65 expression and remained out of the cell cycle. The HESC-RPE cells responded to the in vivo environment by downregulating Pax6, while maintaining expression of other markers. The presence of rhodopsin-positive material within grafted HESC-RPE indicates that in the future, homogenous transplants of this cell type may be capable of supporting visual function following retinal dystrophy.

  6. Molecular nuclear imaging of tumoral angio genesis using a rgd-containing tracer, Raft-RGD, targeted at the neo vessel-specific integrin {alpha}{sub v}{beta}{sub 3}; Evaluation d'un radioligand de l'integrine {alpha}{sub v}{beta}{sub 3} (RAFT-RGD) pour l'imagerie moleculaire de l'angiogenese tumorale

    Energy Technology Data Exchange (ETDEWEB)

    Sancey, L

    2006-06-15

    Tumoral neo-angio genesis targeting is currently a major field of research for the diagnostic and treatment of solid tumors. Endothelial cells from neo vessels over express several specific markers such as the {alpha}{sub v}{beta}{sub 3} integrin, which binds RGD (-Arg-Gly-Asp-)- containing peptides. We evaluated the potential of a novel radiotracer - RAFT-RGD - for the molecular nuclear imaging of neo vessels. In vitro, the coupling of 4 c(RGDfK) to the RAFT platform resulted in an increased cellular uptake of the tracer by {alpha}{sub v}{beta}{sub 3} positive cells when compared to c(RGDfK). Furthermore, RAFTRGD has a higher affinity than c(RGDfK) and similar properties for angio genesis inhibition. In vivo, both {alpha}{sub v}{beta}{sub 3} positive and negative tumors were visible by non invasive whole body planar and tomographic imaging from 30 min to 24 h post-injection, using a gamma camera dedicated to small animal imaging. Despite a lack of significant contrast improvement compare with c(RGDfK), RAFT-RGD could represent a promising tracer for tumoral angio genesis since it could provide invaluable information about tumor development and treatment efficacy in Nuclear Medicine departments. Furthermore, thanks to its chemical structure, RAFT-RGD can be labelled with a variety of radioisotopes including {gamma} and {beta}{sup -} emitters, allowing interesting therapeutical applications such as internal targeted radiotherapy. (author)

  7. The added value of biomarker analysis to the genesis of Plaggic Anthrosols.

    Science.gov (United States)

    van Mourik, Jan; Jansen, Boris

    2015-04-01

    Coversands (chemical poor Late-glacial aeolian sand deposits) dominate the surface geology of an extensive area in northwestern Europe. Plaggic Anthrosols occur in cultural landscapes, developed on coversands. They are the characteristic soils that developed on ancient fertilized arable fields. Plaggic Anthrosols have a complex genesis. They are records of aspects environmental and agricultural history. In previous studies information of the soil records was unlocked by application of pollen analysis, 14C and OSL dating. In this study we applied biomarker analysis to unlock additional information about the applied organic sources in the production of plaggic manure. Radiocarbon dating suggested the start of sedentary agriculture (after a period, characterized by shifting cultivation and Celtic fields) between 3000 and 2000 BP. In previous studies is assumed that farmers applied organic sods, dug on forest soils and heath to produce organic stable manure to fertilize the fields. The mineral fraction of the sods was supposed to be responsible for the development of the plaggic horizon and the raise of the land surface. Optically stimulated Luminescence dating however suggested that plaggic deposition on the fields started relatively late, in the 18th century. The use of ectorganic matter from the forest soils must have been ended in the 10th-12th century, due to commercial forest clear cuttings as recorded in archived documents. These deforestations resulted in the first extension of sand drifting and famers had to protect the valuable heath against this ' environmental catastrophe' . The use of heath for sheep grazing and other purposes as honey production could continue till the 18th century, as recorded in archived documents. In the course of the 18th century, the population growth resulted in increasing demand for food. The deep stable economy was introduced and the booming demand for manure resulted in intensive sod digging on the heath. This caused heath

  8. Prediction of cesarean delivery in the term nulliparous woman: results from the prospective, multicenter Genesis study.

    Science.gov (United States)

    Burke, Naomi; Burke, Gerard; Breathnach, Fionnuala; McAuliffe, Fionnuala; Morrison, John J; Turner, Michael; Dornan, Samina; Higgins, John R; Cotter, Amanda; Geary, Michael; McParland, Peter; Daly, Sean; Cody, Fiona; Dicker, Pat; Tully, Elizabeth; Malone, Fergal D

    2017-06-01

    In contemporary practice many nulliparous women require intervention during childbirth such as operative vaginal delivery or cesarean delivery (CD). Despite the knowledge that the increasing rate of CD is associated with increasing maternal age, obesity and larger infant birthweight, we lack a reliable method to predict the requirement for such potentially hazardous obstetric procedures during labor and delivery. This issue is important, as there are greater rates of morbidity and mortality associated with unplanned CD performed in labor compared with scheduled CDs. A prediction algorithm to identify women at risk of an unplanned CD could help reduced labor associated morbidity. In this primary analysis of the Genesis study, our objective was to prospectively assess the use of prenatally determined, maternal and fetal, anthropomorphic, clinical, and ultrasound features to develop a predictive tool for unplanned CD in the term nulliparous woman, before the onset of labor. The Genesis study recruited 2336 nulliparous women with a vertex presentation between 39+0 and 40+6 weeks' gestation in a prospective multicenter national study to examine predictors of CD. At recruitment, a detailed clinical evaluation and ultrasound assessment were performed. To reduce bias from knowledge of these data potentially influencing mode of delivery, women, midwives, and obstetricians were blinded to the ultrasound data. All hypothetical prenatal risk factors for unplanned CD were assessed as a composite. Multiple logistic regression analysis and mathematical modeling was used to develop a risk evaluation tool for CD in nulliparous women. Continuous predictors were standardized using z scores. From a total enrolled cohort of 2336 nulliparous participants, 491 (21%) had an unplanned CD. Five parameters were determined to be the best combined predictors of CD. These were advancing maternal age (odds ratio [OR], 1.21; 95% confidence interval [CI], 1.09 to 1.34), shorter maternal height (OR

  9. Study on the uranium mineralization genesis of the Cachoeira, Lagoa Real, Bahia, mine, as auxiliary in the discovery and comprehension of mineral beds; Estudo da genese da mineralizacao uranifica da mina da Cachoeira, Lagoa Real, BA, como auxilio na descoberta e compreensao de jazidas minerais

    Energy Technology Data Exchange (ETDEWEB)

    Oliveira, Lucilia Aparecida Ramos de; Rios, Francisco Javier; Chaves, Alexandre de Oliveira; Pereira, Ana Rosa Passos [Centro de Desenvolvimento da Tecnologia Nuclear (CDTN/CNEN-MG), Belo Horizonte, MG (Brazil)]. E-mail: laro@cdtn.br

    2007-07-01

    The acknowledgement of the geological history of a ore reserve allows to infer relative to a large area with possibility to contain the large mineral content or even give the localization of new anomalies or mineral reserve. The study of ore reserve genesis is of great importance for the stages to obtain the mineral, from the prospection until the mineral mining. Fluid inclusions (FI) are fluid quantities which are imprison in the minerals during the formation process or some process where deformation occurs. The study of fluid inclusions, together with the petrographic mapping of the blades associated to the uranium para genesis of Lagoa Real, Brazil, are been used for a better comprehension of the uranium orogenesis. The main analysis techniques used in this context were the petrography and microthermometry. With the petrographic analysis fluid inclusions were observed and mapped in various minerals present in rocks associated to uranium mineralization, such as amphiboles, pyroxenes and grenades. The micro thermometric studies were only performed in the pyroxenes and the grenades due to the fluid inclusions types found in these minerals, and also the supposed relationships that those minerals have with uranium mineralization at that region. (author)

  10. Weathering and genesis of Soils from Ellsworth Mountains, East Antarctica

    Science.gov (United States)

    Karoline Delpupo Souza, Katia; Schaefer, Carlos Ernesto; Michel, Roberto; Monari, Julia; Machado, Vania

    2015-04-01

    Knowledge on Antarctic soils from the Ellsworth Mountains (EM) are patchy comparatively with Dry Valleys soils from the Transantartic Mountains, and could help understand the genesis of cryogenic soils under extreme dry, cold desert conditions. The EM are a slightly arcuate 350-km-long north-northwest-trending mountain chain is bordered on the west by the polar plateau of West Antarctica and on the east by Ronne Ice Shelf. The range is as much as 90 km wide and constitutes one of the largest areas of exposed bedrock in West Antarctica. The stratigraphic succession in the EM includes strata from Cambriam to Permian in age. The objective of this study is to analyze the properties of soils from EM in order to identify the main factors and processes involved in soil formation under cold desert conditions in Antarctica. The sampling design aimed to represent the different geological substrates (marble-clast conglomerate, graywacke, argillite, conglomerate, black shale, marble and quartzite) as well as altitudinal levels and landforms within the same substrate. We characterized soils from EM regarding their morphological, physics and chemical properties. Soil samples were air dried and passed through 2 mm sieves. After removal of water soluble salts, the samples were submitted to chemical and physical analyses such as: pH in water, potential acidity (H + Al), exchangeable bases, total organic carbon, electric conductivity, soil texture and color. The soils classify, for the most part, in weathering stages 1 to 2. Only in the upper parts of ridges were there traces of soils at weathering stage 3. This indicates that much of the present icefree topography has been overridden by ice within the last few hundred thousand years. Cryoturbation is a widespread phenomenon in this area resulting in intense cryoclastic weathering and patterned ground, forming sorted circles, stripes and gelifluxion lobes. The soil show low horizontation, discrete patches of salt on the surface, and

  11. GENESIS SciFlo: Choreographing Interoperable Web Services on the Grid using a Semantically-Enabled Dataflow Execution Environment

    Science.gov (United States)

    Wilson, B. D.; Manipon, G.; Xing, Z.

    2007-12-01

    The General Earth Science Investigation Suite (GENESIS) project is a NASA-sponsored partnership between the Jet Propulsion Laboratory, academia, and NASA data centers to develop a new suite of Web Services tools to facilitate multi-sensor investigations in Earth System Science. The goal of GENESIS is to enable large-scale, multi-instrument atmospheric science using combined datasets from the AIRS, MODIS, MISR, and GPS sensors. Investigations include cross-comparison of spaceborne climate sensors, cloud spectral analysis, study of upper troposphere-stratosphere water transport, study of the aerosol indirect cloud effect, and global climate model validation. The challenges are to bring together very large datasets, reformat and understand the individual instrument retrievals, co-register or re-grid the retrieved physical parameters, perform computationally-intensive data fusion and data mining operations, and accumulate complex statistics over months to years of data. To meet these challenges, we have developed a Grid computing and dataflow framework, named SciFlo, in which we are deploying a set of versatile and reusable operators for data access, subsetting, registration, mining, fusion, compression, and advanced statistical analysis. SciFlo leverages remote Web Services, called via Simple Object Access Protocol (SOAP) or REST (one-line) URLs, and the Grid Computing standards (WS-* & Globus Alliance toolkits), and enables scientists to do multi- instrument Earth Science by assembling reusable Web Services and native executables into a distributed computing flow (tree of operators). The SciFlo client & server engines optimize the execution of such distributed data flows and allow the user to transparently find and use datasets and operators without worrying about the actual location of the Grid resources. In particular, SciFlo exploits the wealth of datasets accessible by OpenGIS Consortium (OGC) Web Mapping Servers & Web Coverage Servers (WMS/WCS), and by Open Data

  12. From an Enclosure to the Corraleja. An Analysis of the Genesis of an Ephemeral and Vernacular Colombian Architecture

    Directory of Open Access Journals (Sweden)

    Massimo Leserri

    2018-03-01

    suggests that, from long time ago, many examples of tectonic building (a set of finite or pseudo-finite elements such as branches, trunks, etc. have been nomadic, self-constructed, anonymous and with an emergency appearance which have become stable, just after many constructions, by losing all ephemeral characteristics. Likewise, to understand the Corralejas’ genesis, observing the history of European architecture has been necessary due to the several old associated experiences of transitory constructions, e.g., with recreational spaces, religious or civil celebrations. This study is based on different research methodologies such as drawings of existing cases and bibliographic and iconographic analyzes. This has also been developed through a compulsory contrast with the ancient architecture of bullfighting shows, to formulate morphological reflections and analogies and analyze their ephemeral condition. Today, the Corraleja survives in Colombia, representing an architectural oddity that must be safeguarded not only for its vernacular essence but also for its limited temporal condition. In fact, tectonics, the art of montage, reconfirms the connection allowing its existence and representing a surprising and unique set of values that must be defended and treated as an architectural heritage. After the analysis on the Corralejas genesis, the study will continue through several forms of survey to explore and define constructive aspects in a different scale of detail.

  13. Long-chain polyunsaturated fatty acids (LCPUFA) from genesis to senescence: the influence of LCPUFA on neural development, aging, and neurodegeneration.

    Science.gov (United States)

    Janssen, Carola I F; Kiliaan, Amanda J

    2014-01-01

    Many clinical and animal studies demonstrate the importance of long-chain polyunsaturated fatty acids (LCPUFA) in neural development and neurodegeneration. This review will focus on involvement of LCPUFA from genesis to senescence. The LCPUFA docosahexaenoic acid and arachidonic acid are important components of neuronal membranes, while eicosapentaenoic acid, docosahexaenoic acid, and arachidonic acid also affect cardiovascular health and inflammation. In neural development, LCPUFA deficiency can lead to severe disorders like schizophrenia and attention deficit hyperactivity disorder. Perinatal LCPUFA supplementation demonstrated beneficial effects in neural development in humans and rodents resulting in improved cognition and sensorimotor integration. In normal aging, the effect of LCPUFA on prevention of cognitive impairment will be discussed. LCPUFA are important for neuronal membrane integrity and function, and also contribute in prevention of brain hypoperfusion. Cerebral perfusion can be compromised as result of obesity, cerebrovascular disease, hypertension, or diabetes mellitus type 2. Last, we will focus on the role of LCPUFA in most common neurodegenerative diseases like Alzheimer's disease and Parkinson's disease. These disorders are characterized by impaired cognition and connectivity and both clinical and animal supplementation studies have shown the potential of LCPUFA to decrease neurodegeneration and inflammation. This review shows that LCPUFA are essential throughout life. Copyright © 2013 Elsevier Ltd. All rights reserved.

  14. Genesis of a novel Shigella flexneri serotype by sequential infection of serotype-converting bacteriophages SfX and SfI

    Directory of Open Access Journals (Sweden)

    Sun Qiangzheng

    2011-12-01

    Full Text Available Abstract Background Shigella flexneri is the major pathogen causing bacillary dysentery. Fifteen serotypes have been recognized up to now. The genesis of new S. flexneri serotypes is commonly mediated by serotype-converting bacteriophages. Untypeable or novel serotypes from natural infections had been reported worldwide but have not been generated in laboratory. Results A new S. flexneri serotype-serotype 1 d was generated when a S. flexneri serotype Y strain (native LPS was sequentially infected with 2 serotype-converting bacteriophages, SfX first and then SfI. The new serotype 1 d strain agglutinated with both serotype X-specific anti-7;8 grouping serum and serotype 1a-specific anti- I typing serum, and differed from subserotypes 1a, 1b and 1c. Twenty four S. flexneri clinical isolates of serotype X were all converted to serotype 1 d by infection with phage SfI. PCR and sequencing revealed that SfI and SfX were integrated in tandem into the proA-yaiC region of the host chromosome. Conclusions These findings suggest a new S. flexneri serotype could be created in nature. Such a conversion may be constrained by susceptibility of a strain to infection by a given serotype-converting bacteriophage. This finding has significant implications in the emergence of new S. flexneri serotypes in nature.

  15. Isotopic and trace element constraints on the genesis of a boninitic sequence in the Thetford Mines ophiolitic complex, Quebec, Canada

    International Nuclear Information System (INIS)

    Olive, V.; Hebert, R.; Loubet, M.

    1997-01-01

    The Mont Ham Massif (part of the Thetford Mines ophiolite, south Quebec) represents a magmatic sequence made up of tholeiitic and boninitic derived products. A geochemical study confirms the multicomponent mixing models that have been classically advanced for the source of boninites, with slab-derived components added to the main refractory harzburgitic peridotite. An isochron diagram of the boninitic rocks is interpreted as a mixing trend between two components: (i) a light rare earth element (LREE) enriched component (A), interpreted as slab-derived fluid-melts equilibrated with sedimentary materials (ε Nd = -3, 147 Sm/ 144 Nd = 0.140), and (ii) a LREE-depleted component (B) (0.21 147 Sm/ 144 Nd Nd = 9). A multicomponent source is also necessary to explain the Nd-isotope and trace element composition of the tholeiites, which are explained by the melting of a more fertile, Iherzolitic mantle and (or) mid-ocean ridge basalt source (component C), characterized by a large-ion lithophile element depicted pattern and an lapetus mantle Nd isotopic composition (ε Nd = 9), mixed in adequate proportions with the two previously infered slab-derived components (A and B). The genesis of the boninites of Mont Ham is not significantly different from those of boninites located in the Pacific. An intraoceanic subduction zone appears to be an appropriate geodynamic environment for the Mont Ham ophiolitic sequence. (author)

  16. Petrography, Geochemistry and Proposed Genesis of Ordovician Oolitic Iron Formation Members of the Lashkarak Formation, Eastern Alborz

    International Nuclear Information System (INIS)

    Maghsoudloo Mahalli, M.; Shafiei Bafti, B.

    2016-01-01

    Mineralogical characteristics combined with geochemical data show that anomalous values of Fe in studied carbonate argillite formations with respect to common sedimentary rocks are related to the abundance of iron-bearing oolites as oxides such as hematite and goethite, and the clay mineral chamosite. Based on Fe, Mg and Ca concentrations, oolitic iron formations can be divided into low-grade and high-grade iron formations. The former is characterized by chamosite and calcite, whereas the latter consists ofhematite and calcite. This research, along with available paleo-geographic and sedimentological information suggests that the iron for the formation of iron oolites was available from normal sea water and Fe could be carried as clastic particles along with clays or coating of clay particles derived from weathering and erosion of shales from adjacent land. High contents of K and Si in oolitic iron horizons, the presence of detrital zircon, quartz and clay minerals within oolites and also in the matrix of these rocks confirm the proposed model and show the important role of Fe-bearing clay minerals in the genesis of the primary chamositic oolites in an environment with p H=5-9 and medium-weak redox conditions (Maynard, 1983; Maynard, 1986). The abundance of hematite relative to goethite in the Fe-oolites, dense and elliptical oolites as well as the frequent occurrence of calcite veinlets cutting oolite beds has been attributed to diagenetic processes and the modification of chamosite and goethite to hematite. Our findings indicate that the studied members can be classified as low-grade oolitic iron formation (average 21 wt.% Fe) which do not have economic importance at present.

  17. Estudio del proceso de génesis instrumental del artefacto simbólico función exponencial Study of the process of instrumental genesis of the symbolic artifact for the exponential function

    Directory of Open Access Journals (Sweden)

    Mihály André Martínez Miraval

    2018-05-01

    Full Text Available This article describes a study of the exponential function on students of the first semester of a private University in Lima, Peru. The research was aimed at analyzing the Instrumental genesis process of this mathematical object assisted by the use of Geogebra software. Rabardel's Instrumental Approach was used as a theoretical framework. Likewise, some notions of Artigue's Didactic Engineering were used as a methodology, focusing on a priori and a posteriori analysis. The students’ answers allowed to identify the use of schemes built and activated, while interacting with the symbolic artifact for the exponential function. The use of Geogebra favored the instrumentalization and instrumentation of the addressed mathematical object since it allowed the students to validate their conjectures. Keywords:

  18. Genesis of the gossan at the Las Cruces Ore Deposit (SW Spain). Groundwater-Rock Interaction.

    Science.gov (United States)

    Scheiber, L.; Ayora, C.; Vázquez-Suñé, E.; Soler, A.

    2016-12-01

    The Las Cruces deposit has sparked an interest in the scientific community due to the exceptional genesis and mineralogical composition. The original gossan formed by goethite and hematite has been replaced by siderite and galena rock. The current gossan composition is as the result of the interaction of groundwater that circulates through the Niebla-Posadas aquifer and a gossan formed by Fe-oxyhydroxides. The groundwater conditions promoted the reductive dissolution of Pb-bearing goethite by the organic matter degradation and the formation of siderite and galena. Hydrochemical and isotopic characteristics of groundwater endorses this hypothesis. Thus, negative Eh values, the existence of H2S and the tendency to light sulfate isotope values show the reducing conditions of groundwater. The key role of the organic matter degradation is marked by the high ammonium, boron and dissolved organic carbon (DOC) concentrations together the light δ13C values, both in groundwater and siderite. The siderite precipitation is confirmed by the high pH values (up to 10), the low amount of Fe (<10ppb) and the thermodynamic calculations. The Fe-oxyhydroxides are a high adsorption capacity which is capable of absorbing metals as arsenic, lead and antimony. The reductive dissolution of these minerals involves the release of these metal to groundwater. Then, the groundwater rich in sulfur and an excess of lead produce the galena precipitation. The likeness between the δ34S values, both the gossan and groundwater, reveals that the sulfur of the galena come from the currently groundwater. A reactive transport model confirm that the present day groundwater flux and composition is able to form the siderite rock in less than 1Ma, with no external supply of reactants. The limiting factor of the process is the Dissolved Organic Carbon (DOC) concentration in groundwater, i.e., higher concentrations would decrease the formation time, whereas the result is not sensitive to flow conditions.

  19. Sr-Nd-Pb isotopic constraints on the nature of the mantle sources involved in the genesis of the high-Ti tholeiites from northern Paraná Continental Flood Basalts (Brazil)

    Science.gov (United States)

    Rocha-Júnior, Eduardo R. V.; Marques, Leila S.; Babinski, Marly; Nardy, Antônio J. R.; Figueiredo, Ana M. G.; Machado, Fábio B.

    2013-10-01

    There has been little research on geochemistry and isotopic compositions in tholeiites of the Northern region from the Paraná Continental Flood Basalts (PCFB), one of the largest continental provinces of the world. In order to examine the mantle sources involved in the high-Ti (Pitanga and Paranapanema) basalt genesis, we studied Sr, Nd, and Pb isotopic systematics, and major, minor and incompatible trace element abundances. The REE patterns of the investigated samples (Pitanga and Paranapanema magma type) are similar (parallel to) to those of Island Arc Basalts' REE patterns. The high-Ti basalts investigated in this study have initial (133 Ma) 87Sr/86Sr ratios of 0.70538-0.70642, 143Nd/144Nd of 0.51233-0.51218, 206Pb/204Pb of 17.74-18.25, 207Pb/204Pb of 15.51-15.57, and 208Pb/204Pb of 38.18-38.45. These isotopic compositions do not display any correlation with Nb/Th, Nb/La or P2O5/K2O ratios, which also reflect that these rocks were not significantly affected by low-pressure crustal contamination. The incompatible trace element ratios and Sr-Nd-Pb isotopic compositions of the PCFB tholeiites are different to those found in Tristan da Cunha ocean island rocks, showing that this plume did not play a substantial role in the PCFB genesis. This interpretation is corroborated by previously published osmium isotopic data (initial γOs values range from +1.0 to +2.0 for high-Ti basalts), which also preclude basalt generation by melting of ancient subcontinental lithospheric mantle. The geochemical composition of the northern PCFB may be explained through the involvement of fluids and/or small volume melts related to metasomatic processes. In this context, we propose that the source of these magmas is a mixture of sublithospheric peridotite veined and/or interlayered with mafic components (e.g., pyroxenites or eclogites). The sublithospheric mantle (dominating the osmium isotopic compositions) was very probably enriched by fluids and/or magmas related to the

  20. Genesis of Pb-Zn-Cu-Ag Deposits within Permian Carboniferous-Carbonate Rocks in Madina Regency, North Sumatra

    Directory of Open Access Journals (Sweden)

    Bhakti Hamonangan Harahap

    2015-09-01

    Full Text Available DOI:10.17014/ijog.2.3.167-184Strong mineralized carbonate rock-bearing Pb-Zn-Cu-Ag-(Au ores are well exposed on the Latong River area, Madina Regency, North Sumatra Province. The ore deposit is hosted within the carbonate rocks of the Permian to Carboniferous Tapanuli Group. It is mainly accumulated in hollows replacing limestone in the forms of lensoidal, colloform, veins, veinlets, cavity filling, breccia, and dissemination. The ores dominantly consist of galena (126 000 ppm Pb and sphalerite (2347 ppm Zn. The other minerals are silver, azurite, covellite, pyrite, marcasite, and chalcopyrite. This deposit was formed by at least three phases of mineralization, i.e. pyrite and then galena replaced pyrite, sphalerite replaced galena, and pyrite. The last phase is the deposition of chalcopyrite that replaced sphalerite. The Latong sulfide ore deposits posses Pb isotope ratio of 206Pb/204Pb = 19.16 - 20.72, 207Pb/204Pb = 16.16 - 17.29, and 208Pb/204Pb = 42.92 - 40.78. The characteristic feature of the deposit indicates that it is formed by a sedimentary process rather than an igneous activity in origin. This leads to an interpretation that the Latong deposit belongs to the Sedimentary Hosted Massive Sulfide (SHMS of Mississippi Valley-Type (MVT. The presence of SHMS in the island arc such as Sumatra has become controversial. For a long time, ore deposits in the Indonesian Island Arc are always identical with the porphyry and hydrothermal processes related to arc magmatism. This paper is dealing with the geology of Latong and its base metal deposits. This work is also to interpret their genesis as well as general relationship to the regional geology and tectonic setting of Sumatra.

  1. Genesis Solar Wind Sample 61422: Experiment in Variation of Sequence of Cleaning Solvent for Removing Carbon-Bearing Contamination

    Science.gov (United States)

    Allton, J. H.; Kuhlman, K. R.; Allums, K. K.; Gonzalez, C. P.; Jurewicz, A. J. G.; Burnett, D. S.; Woolum, D. S.

    2015-01-01

    The recovered Genesis collector fragments are heavily contaminated with crash-derived particulate debris. However, megasonic treatment with ultra-pure-water (UPW; resistivity (is) greater than18 meg-ohm-cm) removes essentially all particulate contamination greater than 5 microns in size [e.g.1] and is thus of considerable importance. Optical imaging of Si sample 60336 revealed the presence of a large C-rich particle after UPW treatment that was not present prior to UPW. Such handling contamination is occasionally observed, but such contaminants are normally easily removed by UPW cleaning. The 60336 particle was exceptional in that, surprisingly, it was not removed by additional UPW or by hot xylene or by aqua regia treatment. It was eventually removed by treatment with NH3-H2O2. Our best interpretation of the origin of the 60336 particle was that it was adhesive from the Post-It notes used to stabilize samples for transport from Utah after the hard landing. It is possible that the insoluble nature of the 60336 particle comes from interaction of the Post-It adhesive with UPW. An occasional bit of Post-It adhesive is not a major concern, but C particulate contamination also occurs from the heat shield of the Sample Return Capsule (SRC) and this is mixed with inorganic contamination from the SRC and the Utah landing site. If UPW exposure also produced an insoluble residue from SRC C, this would be a major problem in chemical treatments to produce clean surfaces for analysis. This paper reports experiments to test whether particulate contamination was removed more easily if UPW treatment was not used.

  2. ISOTOPIC MASS FRACTIONATION OF SOLAR WIND: EVIDENCE FROM FAST AND SLOW SOLAR WIND COLLECTED BY THE GENESIS MISSION

    International Nuclear Information System (INIS)

    Heber, Veronika S.; Baur, Heinrich; Wieler, Rainer; Bochsler, Peter; McKeegan, Kevin D.; Neugebauer, Marcia; Reisenfeld, Daniel B.; Wiens, Roger C.

    2012-01-01

    NASA's Genesis space mission returned samples of solar wind collected over ∼2.3 years. We present elemental and isotopic compositions of He, Ne, and Ar analyzed in diamond-like carbon targets from the slow and fast solar wind collectors to investigate isotopic fractionation processes during solar wind formation. The solar wind provides information on the isotopic composition for most volatile elements for the solar atmosphere, the bulk Sun and hence, on the solar nebula from which it formed 4.6 Ga ago. Our data reveal a heavy isotope depletion in the slow solar wind compared to the fast wind composition by 63.1 ± 2.1 per mille for He, 4.2 ± 0.5 per mille amu –1 for Ne and 2.6 ± 0.5 per mille amu –1 for Ar. The three Ne isotopes suggest that isotopic fractionation processes between fast and slow solar wind are mass dependent. The He/H ratios of the collected slow and fast solar wind samples are 0.0344 and 0.0406, respectively. The inefficient Coulomb drag model reproduces the measured isotopic fractionation between fast and slow wind. Therefore, we apply this model to infer the photospheric isotopic composition of He, Ne, and Ar from our solar wind data. We also compare the isotopic composition of oxygen and nitrogen measured in the solar wind with values of early solar system condensates, probably representing solar nebula composition. We interpret the differences between these samples as being due to isotopic fractionation during solar wind formation. For both elements, the magnitude and sign of the observed differences are in good agreement with the values predicted by the inefficient Coulomb drag model.

  3. ISOTOPIC MASS FRACTIONATION OF SOLAR WIND: EVIDENCE FROM FAST AND SLOW SOLAR WIND COLLECTED BY THE GENESIS MISSION

    Energy Technology Data Exchange (ETDEWEB)

    Heber, Veronika S.; Baur, Heinrich; Wieler, Rainer [Institute for Geochemistry and Petrology, ETH Zurich, Clausiusstrasse 25, CH-8092 Zurich (Switzerland); Bochsler, Peter [Physikalisches Institut, Universitaet Bern, Sidlerstasse 5, CH-3012 Bern (Switzerland); McKeegan, Kevin D. [Department of Earth and Space Sciences, University of California Los Angeles, 595 Charles Young Drive East, Box 951567, Los Angeles, CA 90095-1567 (United States); Neugebauer, Marcia [Lunar and Planetary Laboratory, University of Arizona, Tucson, AZ 85721-0092 (United States); Reisenfeld, Daniel B. [Department of Physics and Astronomy, University of Montana, Missoula, MT 59812 (United States); Wiens, Roger C., E-mail: heber@ess.ucla.edu [Los Alamos National Laboratory, Los Alamos, NM 87545 (United States)

    2012-11-10

    NASA's Genesis space mission returned samples of solar wind collected over {approx}2.3 years. We present elemental and isotopic compositions of He, Ne, and Ar analyzed in diamond-like carbon targets from the slow and fast solar wind collectors to investigate isotopic fractionation processes during solar wind formation. The solar wind provides information on the isotopic composition for most volatile elements for the solar atmosphere, the bulk Sun and hence, on the solar nebula from which it formed 4.6 Ga ago. Our data reveal a heavy isotope depletion in the slow solar wind compared to the fast wind composition by 63.1 {+-} 2.1 per mille for He, 4.2 {+-} 0.5 per mille amu{sup -1} for Ne and 2.6 {+-} 0.5 per mille amu{sup -1} for Ar. The three Ne isotopes suggest that isotopic fractionation processes between fast and slow solar wind are mass dependent. The He/H ratios of the collected slow and fast solar wind samples are 0.0344 and 0.0406, respectively. The inefficient Coulomb drag model reproduces the measured isotopic fractionation between fast and slow wind. Therefore, we apply this model to infer the photospheric isotopic composition of He, Ne, and Ar from our solar wind data. We also compare the isotopic composition of oxygen and nitrogen measured in the solar wind with values of early solar system condensates, probably representing solar nebula composition. We interpret the differences between these samples as being due to isotopic fractionation during solar wind formation. For both elements, the magnitude and sign of the observed differences are in good agreement with the values predicted by the inefficient Coulomb drag model.

  4. The giant Bayan Obo REE-Nb-Fe deposit, China: Controversy and ore genesis

    Directory of Open Access Journals (Sweden)

    Hong-Rui Fan

    2016-05-01

    Full Text Available Bayan Obo ore deposit is the largest rare-earth element (REE resource, and the second largest niobium (Nb resource in the world. Due to the complicated element/mineral compositions and involving several geological events, the REE enrichment mechanism and genesis of this giant deposit still remains intense debated. The deposit is hosted in the massive dolomite, and nearly one hundred carbonatite dykes occur in the vicinity of the deposit. The carbonatite dykes can be divided into three types from early to late: dolomite, co-existing dolomite-calcite and calcite type, corresponding to different evolutionary stages of carbonatite magmatism based on the REE and trace element data. The latter always has higher REE content. The origin of the ore-hosting dolomite at Bayan Obo has been addressed in various models, ranging from a normal sedimentary carbonate rocks to volcano-sedimentary sequence, and a large carbonatitic intrusion. More geochemical evidences show that the coarse-grained dolomite represents a Mesoproterozoic carbonatite pluton and the fine-grained dolomite resulted from the extensive REE mineralization and modification of the coarse-grained variety. The ore bodies, distributed along an E–W striking belt, occur as large lenses and underwent more intense fluoritization and fenitization. The first episode mineralization is characterized by disseminated mineralization in the dolomite. The second or main-episode is banded and/or massive mineralization, cut by the third episode consisting of aegirine-rich veins. Various dating methods gave different mineralization ages at Bayan Obo, resulting in long and hot debates. Compilation of available data suggests that the mineralization is rather variable with two peaks at ∼1400 and 440 Ma. The early mineralization peak closes in time to the intrusion of the carbonatite dykes. A significant thermal event at ca. 440 Ma resulted in the formation of late-stage veins with coarse crystals of REE

  5. Interannual variability of the South Pacific Convergence Zone and implications for tropical cyclone genesis

    Energy Technology Data Exchange (ETDEWEB)

    Vincent, Emmanuel M. [IRD/UPMC/CNRS/MNHN, Laboratoire d' Oceanographie et du Climat: Experimentation et Approches Numeriques (LOCEAN), Paris (France); UPMC, LOCEAN/IPSL, Paris Cedex 05 (France); Lengaigne, Matthieu [IRD/UPMC/CNRS/MNHN, Laboratoire d' Oceanographie et du Climat: Experimentation et Approches Numeriques (LOCEAN), Paris (France); National Institute of Oceanography, Goa (India); Menkes, Christophe E. [IRD/UPMC/CNRS/MNHN, Laboratoire d' Oceanographie et du Climat: Experimentation et Approches Numeriques (LOCEAN), Paris (France); Institut de Recherche pour le Developpement, Noumea (New Caledonia); Jourdain, Nicolas C. [Institut de Recherche pour le Developpement, Noumea (New Caledonia); Marchesiello, Patrick [Institut de Recherche pour le Developpement, Noumea (New Caledonia); CNES/CNRS/UPS/IRD, Laboratoire d' Etudes en Geophysique et Oceanographie Spatiale (LEGOS), Toulouse (France); Madec, Gurvan [IRD/UPMC/CNRS/MNHN, Laboratoire d' Oceanographie et du Climat: Experimentation et Approches Numeriques (LOCEAN), Paris (France); National Oceanographic Centre, Southampton (United Kingdom)

    2011-05-15

    The interannual variability of the South Pacific Convergence Zone (SPCZ) and its influence on tropical cyclone (TC) genesis in the South Pacific are investigated using observations and ERA40 reanalysis over the 1979-2002 period. In austral summer, the SPCZ displays four typical structures at interannual timescales. The first three are characterized by a diagonal orientation of the SPCZ and account for 85% of the summer seasons. One is close to climatology and the other two exhibit a 3 northward or southward departure from the SPCZ climatological position. In contrast, the fourth one, that only encompasses three austral summer seasons (the extreme 1982/1983 and 1997/1998 El Nino events and the moderate 1991/1992 El Nino event), displays very peculiar behaviour where the SPCZ largely departs from its climatological position and is zonally oriented. Variability of the western/central Pacific equatorial sea surface temperature (SST) is shown to modulate moisture transport south of the equator, thereby strongly constraining the location of the SPCZ. The SPCZ location is also shown to strongly modulate the atmospheric circulation variability in the South Pacific with specific patterns for each class. However, independently of its wide year-to-year excursions, the SPCZ is always collocated with the zero relative vorticity at low levels while the maximum vorticity axis lies 6 to the south of the SPCZ position. This coherent atmospheric organisation in the SPCZ region is shown to constrain tropical cyclogenesis to occur preferentially within 10 south of the SPCZ location as this region combines all the large-scale atmospheric conditions that favour the breeding of TCs. This analysis also reveals that cyclogenesis in the central Pacific (in the vicinity of French Polynesia) only occurs when the SPCZ displays a zonal orientation while this observation was previously attributed to El Nino years in general. Different characteristics of El Nino Southern Oscillation (ENSO

  6. Caspase-1 is involved in the genesis of inflammatory hypernociception by contributing to peripheral IL-1β maturation

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    Zamboni Dario S

    2010-10-01

    Full Text Available Abstract Background Caspase-1 is a cysteine protease responsible for the processing and secretion of IL-1β and IL-18, which are closely related to the induction of inflammation. However, limited evidence addresses the participation of caspase-1 in inflammatory pain. Here, we investigated the role of caspase-1 in inflammatory hypernociception (a decrease in the nociceptive threshold using caspase-1 deficient mice (casp1-/-. Results Mechanical inflammatory hypernociception was evaluated using an electronic version of the von Frey test. The production of cytokines, PGE2 and neutrophil migration were evaluated by ELISA, radioimmunoassay and myeloperoxidase activity, respectively. The interleukin (IL-1β and cyclooxygenase (COX-2 protein expression were evaluated by western blotting. The mechanical hypernociception induced by intraplantar injection of carrageenin, tumour necrosis factor (TNFα and CXCL1/KC was reduced in casp1-/- mice compared with WT mice. However, the hypernociception induced by IL-1β and PGE2 did not differ in WT and casp1-/- mice. Carrageenin-induced TNF-α and CXCL1/KC production and neutrophil recruitment in the paws of WT mice were not different from casp1-/- mice, while the maturation of IL-1β was reduced in casp1-/- mice. Furthermore, carrageenin induced an increase in the expression of COX-2 and PGE2 production in the paw of WT mice, but was reduced in casp1-/- mice. Conclusion These results suggest that caspase-1 plays a critical role in the cascade of events involved in the genesis of inflammatory hypernociception by promoting IL-1β maturation. Because caspase-1 is involved in the induction of COX-2 expression and PGE2 production, our data support the assertion that caspase-1 is a key target to control inflammatory pain.

  7. Comparative study of angio genesis radiopharmaceuticals for melanoma detection; Estudo comparativo de radiofarmacos para angiogenese na deteccao de melanoma

    Energy Technology Data Exchange (ETDEWEB)

    Oliveira, Erica Aparecida de

    2011-07-01

    Early diagnosis and treatment of melanoma, a cutaneous tumor with a serious prognosis, is extremely important for optimal clinical outcome. Phage display peptide libraries are a useful screening resource for identifying bioactive peptides that interact with cancer targets. The aim of this study was the evaluation of two technetium-99m tracers for angio genesis detection in melanoma model, using cyclic peguilated pentapeptide with RGD and NGR motifs conjugated with bifunctional chelator MAG3. The conjugated peptides (10 {mu}L of a {mu}g/{mu}L solution) were labeled with technetium-99m using a sodium tartrate buffer. Radiochemical evaluation was done by ITLC and confirmed by HPLC. Partition coefficient was determined and internalization assays were performed in two melanoma cells (B16F10 and SKMEL28). Biodistribution evaluation of the tracers was done in healthy animals at different times and also in mice bearing the tumor cells at 120 min post injection. Blocking studies were also conducted by co-injection of cold peptides. The conjugated showed the same profile in many evaluations. They were radiolabeled with high radiochemical purity (>97%). Both were hydrophilic, with preferential renal excretion. Tumor uptake was higher for human melanoma cells than for murinic melanoma cells, specially for {sup 99m}Tc-MAG3-PEG{sub 8}-c(RGDyK) (7.85{+-}{+-}2.34 %ID/g) at 120 min post injection. The performance of {sup 99m}Tc-MAG{sub 3}-PEG{sub 8}-c(RGDyk) was much better than NGR tracer concerning human melanoma uptake and might be considered in future investigations focusing radiotracers for melanoma diagnosis. (author)

  8. Genesis and classification of soils developed on gabbro in the high reliefs of Maroua region, North Cameroon

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    Désiré Tsozué

    2017-04-01

    Full Text Available The purpose of this work was to examine the genesis, properties and classification of soils resulting from the weathering of gabbro rock in the high reliefs of Maroua in the Far North Region of Cameroon. The studied soils were ~ 2 m thick, made of four horizons which consisted of coarse saprolite, fine saprolite, loose loamy clayey horizon and humiferous horizon. From petrographical view point, at the bottom of the soil profile, the preservation of the bedrock structure was marked by numerous remnants of altered plagioclases shapes. The groundmass was characterized by a double spaced fine, ranging to equal, enaulic c/f related distribution pattern. It was yellowish, characterized by weakly separated granular microstructure in the fine saprolite and had a speckled and cloudy limpidity in the loose loamy clayey horizon. Secondary minerals consisted of montmorilonite, kaolinite, goethite, quartz, gibbsite, lepidocrocite, sepiolite, feldspar and calcite. Globally, Si/Al ratio ranged between 2.85 and 3.24. The chemical index of alteration ranged from 50.95 to 55.27 % while the mineralogical index of alteration values were between 1.90 and 10.54 %. Physicochemically, soil pH varied from slightly acidic to slightly above neutral. Soil organic carbon contents were low to very low. Exchangeable bases contents were high, mostly represented by Ca2+ and Mg2+. The CEC of soils and the CEC of clay were also high, ranging respectively between 53.68 and 82.88 cmol(+.kg-1, and 116.80 and 181.38 cmol(+.kg-1. The studied soils were classified as dystric haplustepts clayey isohyperthermic. They were developed in situ by the collapse of primary mineral structures from the bottom of the coarse saprolite, due to leaching as a result of bisiallitisation and monosiallitisation. This is accompanied by a progressive ferruginization of materials, confirmed by the densification under the microscope of goethitic brown veil from the base to the loamy clay horizon and the

  9. Magnetite as the indicator of ore genesis for the Huangshaping polymetallic deposit, southern Hunan Province, China

    Science.gov (United States)

    Ding, T.; Ma, D.; Lu, J.; Zhang, R.

    2017-12-01

    fluids might have undergone large scale circulation, the extraction from Zn-rich metamorphic basement and Mg, Al-rich strata probably have provided abundant Mg, Al, Zn in the hydrothermal fluids where Group-1 magnetites precipitated. As a conclusion, this study suggests that the compositions of magnetites can be the proxies of ore genesis.

  10. The Genesis of the Urban Culture of the Steppe of the Volga Region and Sociocultural Development of the Region

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    Nadezhda V. Dulina

    2016-06-01

    Full Text Available The article is devoted to the problems of the genesis of socio-historical processes of urban culture of the steppe of the Volga region, is based on historical documents, materials of scientific expeditions conducted in the lower Volga region encyclopedic scientists from the second half of the XVIII century, and the results of archaeological research here settlement sites. Based on the fact that the whole history of mankind is the history of the reference person of its economy, the authors believe that the analysis of the spaces of the modern city must be waged simultaneously in multiple coordinate systems – involving knowledge of scientific disciplines such as history and archeology, sociology, Economics etc. Attention is focused on the events in the Volga steppes of socio-economic and cultural-historical transformation, reflected in the distinctive dynamics of sociocultural development of the medieval (Khazar, the Golden Horde, Russian and modern cities in the region. The authors come to the following conclusions: the city created (and covered by most throughout the centuries (and even millennia by many generations, carry a spatial-temporal characteristics and the variety of creative ideas that make them diverse, aesthetically balanced. The growth of these cities, like all living things, inevitably threatens the time, which naturally destroys some of their historical (and in fact – "root" part to "make room" for new construction. To the relentless dynamism of our era was not able to destroy formed for many generations the idea that is subordinated to the formation and development of each particular city, you should each time from a separate historical parts of the city (or temporal-spatial "fragments" to try to reproduce it in its entirety, as the unity and integrity, while maintaining its inherent identity.

  11. A formational model for the polygonal terrains of Mars: Taking a crack at the genesis of the Martian polygons

    Science.gov (United States)

    Wenrich, M. L.; Christensen, P. R.

    1993-01-01

    The mechanism for the genesis of the polygonal terrains in Acidalia and Utopia Planitia has long been sought: however, no completely satisfying model was put forth that characterizes the evolution of these complexly patterned terrains. The polygons are roughly hexagonal but some are not entirely enclosed by fractures. These polygonal features range in widths from approximately 5 to 20 km. Several origins were proposed that describe the polygon borders as desiccation cracks, columnar jointing in a cooled lava, or frost-wedge features. These tension-induced cracking hypotheses were addressed by Pechmann, who convincingly disputes these mechanisms of formation based on scale magnitude difficulties and morphology. Pechmann suggests instead that the cracks delineating the 5-20-km-wide polygons on the northern plains of Mars are graben resulting from deep-seated, uniform, horizontal tension. The difficulty with this hypothesis is that no analogous polygonal forms are known to have originated by tectonism on Earth. McGill and Hills propose that the polygonal terrains on Mars resulted from either rapid desiccation of sediments or cooling of volcanics coupled with differential compaction of the material over a buried irregular topographic surface. They suggest that fracturing was enhanced over the areas of positive relief and was suppressed above the topographic lows. McGill and Hills suggest that the spacing of the topographic highs primarily controls the size of the Martian polygons and the physics of the shrinkage process is a secondary concern. Ray et. al. conducted a terrestrial study of patterned ground in periglacial areas of the U.S. to determine the process responsible for polygonal ground formation. They developed a model for polygon formation in which convection of seasonal melt water above a permafrost layer, driven by an unstable density stratification, differentially melts the permafrost interface, causing it to become undulatory.

  12. Diagenesis of amorphous organic matter as an essential aspect of genesis and alteration of tabular-type uranium-vanadium deposits, Colorado Plateau

    International Nuclear Information System (INIS)

    Spirakis, C.S.; Hansley, P.L.

    1987-01-01

    Organic matter was the key to the initial concentration of uranium and vanadium (during the sulfate reduction stage of early diagenesis) in all sandstone-hosted, tabular deposits in the Morrison Formation, Colorado Plateau. In deposits rich in amorphous organic matter, as are many in the Grants uranium region (GUR), diagenesis did not proceed beyond sulfate reduction. In contrast, in organic-poor, chlorite deposits of the Henry Mountains district, 13 C- and 18 O-enriched dolomites preserve evidence of a subsequent methanogenic stage. In these and similar organic-poor deposits in the Slick Rock district and in parts of the GUR, aluminosilicate dissolution (including a distinctive, organic-acid-induced etching of garnets) and growth of coarse-grained coffinite, albite, ankerite, and chlorite suggest diagenesis reached the organic acid stage. Temperature and thermal maturation indicators (vitrinite reflectance, type IIb chlorite, ordered illite/smectite, and fluid inclusion data) are consistent with temperatures of organic-acid stage diagenesis (∼ 100 0 C). The localization of these alterations in and around organic-poor, clay-rich ore; the similarities in type and sequence of these alterations to the normal alteration of organic-bearing sediments; the alteration of iron-titanium oxides (attributed to the action of soluble organic complexes) around both organic-rich and organic-poor deposits; and the gradation from organic-rich to organic-poor, chlorite-rich deposits (in GUR) suggest that (1) amorphous organic matter was involved in the genesis of all of these deposits and (2) differences among deposits may reflect varying degrees of diagenesis of the organic matter

  13. The ESR age of Portlandia arctica shells from glacial deposits of Central Latvia . an answer to a controversy on the age and genesis of their enclosing sediments

    Science.gov (United States)

    Molodkov, Anatoly; Dreimanis, Aleksis; ĀBoltiņš, Ojars; Raukas, Anto

    The occurrence of Portlandia arctica shells in glacigenic sediments of Central Latvia had created a controversy in many publications about (1) their age ranging from the Holsteinian to the Late Weichselian and (2) the genesis of their enclosing sediments: glacial, glaciomarine or marine. Our reinvestigation of the main object of controversy, the Lı¯čupe site, leads to a conclusion that the sedimentary package of diamictons, clays and sands containing Portlandia arctica shells and marine microfossils is a large glacial raft that had been transported and deposited by the Riga lobe during the Weichselian. The electron spin resonance (ESR) ages on five sets of Portlandia arctica shells from the Lı¯čupe and Daugmales Tomēni sites range from 86.0±6.8 to 105.0±9.2 ka BP. These ESR age determinations and the cool climate indicators of the associated microflora and microfauna suggest that their source sediments, probably in the Gulf of Riga, are marine clays of Early Weichselian age, probably correlative to the Brørup Interstadial. In Central Latvia Portlandia arctica shells and their enclosing clay occur resedimented or translocated in glacial deposits during Weichselian glacial advances.

  14. The genesis of Jan Steens painting 'As the old ones sing, so the young ones pipe' from the Gemaeldegalerie Berlin

    International Nuclear Information System (INIS)

    Denker, A.; Kleinert, K.; Laurenze-Landsberg, C.; Reimelt, M.; Schroeder-Smeibidl, B.

    2011-01-01

    In collaboration with the research reactor of the Helmholtz-Zentrum Berlin fuer Materialien und Energie, the Gemaeldegalerie Berlin is the only institute worldwide, which systematically employs the method of Neutron-Activation-Autoradiography to analyze paintings and painting techniques. To date more than 70 paintings were investigated with this effective, non-destructive, and exceptional method. It allows the visualization of structures and layers beneath the top surface and, in addition, enables the identification of elements contained in the pigments. The instrument B8 at the research reactor BER II is dedicated to this research. Jan Steen is one of the prolific artists from the 17th century. Like other artists from that time he produced several versions of one specific topic during life-time. The topic 'As the old ones sing, so the young ones pipe' was painted by Jan Steen in 13 versions. The painting from the Gemaeldegalerie is an exception in this series as it differs in style and content from the other oeuvres. The question arises: why did the artist deviate from his usual scheme? The possible answer is provided by X-ray images and neutron autoradiographs made of the painting, allowing insight into hidden paint layers and, therefore, in the genesis of the painting. Jan Steen did not simply change the composition of the room and the figures. He originally intended an altogether different topic. Assumedly it was supposed to be a so-called merry company, located in a generous, stately room. Many pieces of this sophisticated ambiance have been eliminated from the version visible today; others were modified and integrated into the composition of the new painting. Thus, Jan Steen commenced the topic 'As the old ones sing, so the young ones pipe' from a different context.

  15. Preaching the ‘green gospel’ in our environment: A re-reading of Genesis 1:27-28 in the Nigerian context

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    Chris Manus

    2016-08-01

    Full Text Available The article focuses on the text of Genesis 1:27–28 within its broader context where the author, the Jahwist, describes humankind as charged with the responsibility to fill and to subdue the earth, which has generally been misunderstood by wealth prospectors. Our methodology is a simplified historical and exegetical study of the two verses of the creation narrative in order to join other contemporary theologians to argue the right of humans to treat the nonhuman as private property as source of material wealth is immoral. As we re-read the text, our findings resonate with the contemporary clarion call for respect and protection of the environment such as COP 2015 in Paris. This provides the justification of our title ‘Preaching the green gospel’, especially in the Nigerian oil-rich states and in Africa in general. Whilst the paper presents a disquisition of the global efforts of the church through sensitisation of their members to appreciate the magnitude of the environmental pollution and the apocalypse it holds for the world, it draws attention to the possibility of the envisaged doomsday that may descend on Nigeria and other parts of Africa if the crass environmental degradation and the rate of pollution of flora and fauna are not checked. The paper takes cognisance of the positive views expressed by the evangelists of the ‘New Theology’ in Africa. Whilst the paper raises Biblically friendly ecological awareness in modern Africa, using Nigeria as a contact point, it concludes, inter alia, that the text demands humankind to partake in God’s will for order and peace in the universe as it struggles to maintain the ecological sustainability of mother earth.

  16. GENESIS OF THE PLOT AND THE GENRE OF THE CREATIVE HISTORY OF SHMELEV’S SHORT NOVEL “TOWARD A NEW LIFE”

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    Oksana A. Sosnovskaya

    2015-11-01

    Full Text Available Th e beginning of  Shmelev’s career is associated with children’s literature. In the early 20th century, the writer creates a signifi cant number of  works for children, published in  magazines for young people. In  one of these magazines — “Young Russia” — there was published Shmelev’s story Toward a  new life. Th e article is  devoted to studying the creative history of this story: following the process of origin and genesis of an artistic idea of the text, analyzing the stages of its creation, editions and poetics. Th e working process had two phases and found its refl ection in three editions of the story. At the fi rst stage the writer was working upon a  sketch of the life of contemporary villages. Later this essay became a prehistory of the short novel about a country boy torn out of his ambiance and seeking for his way in life. Not only the genre changed but the  ideological content of the work became extended as well. Th e core idea of the author that is present throughout the story is the idea of scientifi c perception of nature and life, receiving education that is able to improve life of a common man. In the story Toward a new life, focused on representing a social aspect of life, there are revealed the beginnings of the author’s original writing manner, his unique style and language.

  17. Geochemical constraints on genesis of Paleoproterozoic A-type granite in the south margin of North China Craton

    Science.gov (United States)

    Xue, Shuo; Xu, Yang; Ling, Ming-Xing; Kang, Qing-Qing; Jiang, Xiao-Yan; Sun, Sai-Jun; Wu, Kai; Zhang, Zhe-Kun; Luo, Ze-Bin; Liu, Yu-Long; Sun, Weidong

    2018-04-01

    Paleoproterozoic A-type granites are widely outcropped in the North China Craton (NCC), particularly in the Trans-North China Orogen. However, their genesis and tectonic significance remain obscure. Here we report systematic studies on geochronology and geochemical characteristics of A-type granite in Huayangchuan, south margin of the NCC. The samples are enriched in total alkali (K2O + Na2O > 8.97 wt%), and depleted in MgO (0.84-0.93 wt%), CaO (1.28-1.90 wt%) and P2O5 (0.18-0.20 wt%), with high FeOT/MgO (5.69-6.67). They are characterized by high Zr + Y + Nb + Ce values (1293-1392 ppm) and 10,000 × Ga/Al ratios (3.14-3.35), which are typical characteristics of A-type granite. The Huayangchuan A-type granite can be further classified as A1-type subgroup based on particular geochemical features, e.g., low Y/Nb (0.87-1.00) and Yb/Ta (0.88-1.10). High precision zircon U-Pb dating of the A-type granite by secondary ion mass spectrometry (SIMS) yields Paleoproterozoic 207Pb/206Pb ages of 1829.5 ± 2.5 Ma. The low zircon ɛHf(t) values (-6.97 to -10.45), along with zircon Hf model age of 2.7-2.9 Ga, indicate that the Huayangchuan A-type granite was derived from partial melting of the ancient continental crust with contribution of enriched mantle components. The low zircon δ18O composition (4.00 to 6.78‰) indicates that the zircons were crystallized from low δ18O magmas, which derived from the crust metasomatized by low δ18O mantle fluids or melts. The E-W trend A1-type granitic plutons in the NCC are generally outcropped in a rift tectonic regime, which is consistent with the development of the mantle plume in the Xiong'er district. The large volume of basaltic magmas, generated by mantle plume head, underplated the lower continental crust and formed the Huayangchuan A-type granite.

  18. The contribution of the young Cretaceous Caribbean Oceanic Plateau to the genesis of late Cretaceous arc magmatism in the Cordillera Occidental of Ecuador

    Science.gov (United States)

    Allibon, J.; Monjoie, P.; Lapierre, H.; Jaillard, E.; Bussy, F.; Bosch, D.; Senebier, F.

    2008-12-01

    The eastern part of the Cordillera Occidental of Ecuador comprises thick buoyant oceanic plateaus associated with island-arc tholeiites and subduction-related calc-alkaline series, accreted to the Ecuadorian Continental Margin from Late Cretaceous to Eocene times. One of these plateau sequences, the Guaranda Oceanic Plateau is considered as remnant of the Caribbean-Colombian Oceanic Province (CCOP) accreted to the Ecuadorian Margin in the Maastrichtien. Samples studied in this paper were taken from four cross-sections through two arc-sequences in the northern part of the Cordillera Occidental of Ecuador, dated as (Río Cala) or ascribed to (Macuchi) the Late Cretaceous and one arc-like sequence in the Chogòn-Colonche Cordillera (Las Orquídeas). These three island-arcs can clearly be identified and rest conformably on the CCOP. In all four localities, basalts with abundant large clinopyroxene phenocrysts can be found, mimicking a picritic or ankaramitic facies. This mineralogical particularity, although not uncommon in island arc lavas, hints at a contribution of the CCOP in the genesis of these island arc rocks. The complete petrological and geochemical study of these rocks reveals that some have a primitive island-arc nature (MgO values range from 6 to 11 wt.%). Studied samples display marked Nb, Ta and Ti negative anomalies relative to the adjacent elements in the spidergrams characteristic of subduction-related magmatism. These rocks are LREE-enriched and their clinopyroxenes show a tholeiitic affinity (FeO T-TiO 2 enrichment and CaO depletion from core to rim within a single crystal). The four sampled cross-sections through the island-arc sequences display homogeneous initial Nd, and Pb isotope ratios that suggest a unique mantellic source for these rocks resulting from the mixing of three components: an East-Pacific MORB end-member, an enriched pelagic sediment component, and a HIMU component carried by the CCOP. Indeed, the ankaramite and Mg

  19. Genesis of iron-apatite ores in Posht-e-Badam Block (Central Iran) using REE geochemistry

    Science.gov (United States)

    Mokhtari, Mir Ali Asghar; Zadeh, Ghader Hossein; Emami, Mohamad Hashem

    2013-06-01

    Rare earth elements in apatites of different ore types show characteristic patterns which are related to different modes of formation of the ores. Most of the apatite-bearing iron ores are associated with alkaline magmas with LREE/HREE fractionation varying from moderate to steep. Iron-apatite deposits in Posht-e-Badam Block (Central Iran) have a high concentration of REE (more than 1000 ppm up to 2.5%), and show a strong LREE/HREE ratio with a pronounced negative Eu anomaly. This REE pattern is typical of magmatic apatite and quiet distinct from sedimentary apatites (phosphorites) which have a low REE contents and Ce negative anomalies. On the other hand, they are comparable to the REE patterns of apatites in Kiruna-type iron ores in different parts of the world. The REE patterns of apatites, iron-apatite ores and iron ores are similar and only have different REE contents. This similarity indicates a genetic relation for these rocks. Most of the iron-apatite deposits in Central Iran have similar REE patterns too, which in turn show a genetic relation for all of these deposits. This similarity indicates a similar origin and processes in their genesis. There are some small intrusions around some of the iron-apatite deposits that are petrographically identified as syenite and gabbro. These intrusions also have REE patterns similar to that of iron-apatite ores. This demonstrates a genetic relation between these intrusions and iron-apatite ores. The REE patterns of apatites in different deposits of Posht-e-Badam Block iron-apatite ores show an affinity to alkaline to sub-alkaline magmas and rifting environment. The alkaline host rocks of Central Iran iron-apatite ores are clearly related to an extensional setting where rifting was important (SSE-NNW fault lines). A probable source for this large scale ore forming processes is relatively low partial melting of mantle rocks. The ores have originated by magmatic differentiation as a late phase in the volcanic cycle

  20. Nanoscale Study of Clausthalite-Bearing Symplectites in Cu-Au-(U Ores: Implications for Ore Genesis

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    Nicholas D. Owen

    2018-02-01

    Full Text Available Symplectites comprising clausthalite (PbSe and host Cu-(Fe-sulphides (chalcocite, bornite, and chalcopyrite are instructive for constraining the genesis of Cu-Au-(U ores if adequately addressed at the nanoscale. The present study is carried out on samples representative of all three Cu-(Fe-sulphides displaying clausthalite inclusions that vary in size, from a few µm down to the nm-scale (<5 nm, as well as in morphology and inclusion density. A Transmission Electron Microscopy (TEM study was undertaken on foils prepared by Focussed Ion Beam and included atom-scale High-Angle Annular Dark-Field Scanning TEM (HAADF-STEM imaging. Emphasis is placed on phase relationships and their changes in speciation during cooling, as well as on boundaries between inclusions and host sulphide. Three species from the chalcocite group (Cu2–xS are identified as 6a digenite superstructure, monoclinic chalcocite, and djurleite. Bornite is represented by superstructures, of which 2a and 4a are discussed here, placing constraints for ore formation at T > 265 °C. A minimum temperature of 165 °C is considered for clausthalite-bearing symplectites from the relationships with antiphase boundaries in 6a digenite. The results show that alongside rods, blebs, and needle-like grains of clausthalite within the chalcocite that likely formed via exsolution, a second, overprinting set of replacement textures, extending down to the nanoscale, occurs and affects the primary symplectites. In addition, other reactions between pre-existing Se, present in solid solution within the Cu-(Fe-sulphides, and Pb, transported within a fluid phase, account for the formation of composite, commonly pore-attached PbSe and Bi-bearing nanoparticles within the chalcopyrite. The inferred reorganisation of PbSe nanoparticles into larger tetragonal superlattices represents a link between the solid solution and the symplectite formation and represents the first such example in natural materials

  1. Using the GENESYS model quantifying the effect of cropping systems on gene escape from GM rape varieties to evaluate and design cropping systems

    Directory of Open Access Journals (Sweden)

    Colbach Nathalie

    2004-01-01

    Full Text Available Gene flow in rapeseed is a process taking place both in space and over the years and cannot be studied exclusively by field trials. Consequently, the GENESYS model was developed to quantify the effects of cropping systems on transgene escape from rapeseed crops to rapeseed volunteers in neighbour plots and in the subsequent crops. In the present work, this model was used to evaluate the risk of rape harvest contamination by extraneous genes in various farming systems in case of co-existing GM, conventional and organic crops. When 50 % of the rape varieties in the region were transgenic, the rate of GM seeds in non-GM crop harvests on farms with large fields was lower than the 0.9 % purity threshold proposed by the EC for rape crop production (food and feed harvests, but on farms with smaller fields, the threshold was exceeded. Harvest impurity increased in organic farms, mainly because of their small field size. The model was then used to evaluate the consequences of changes in farming practices and to identify those changes reducing harvest contamination. The effects of these changes depended on the field pattern and farming system. The most efficient practices in limiting harvest impurity comprised improved set-aside management by sowing a cover crop in spring on all set-aside fields in the region, permanently banning rape crops and set-aside around seed production fields and (for non-GM farmers clustering farm fields to reduce gene inflow from neighbour fields.

  2. Petrography, Geochemistry and Proposed Genesis of Ordovician Oolitic Iron Formation Members of the Lashkarak Formation, Eastern Alborz

    Directory of Open Access Journals (Sweden)

    Mansoore Maghsoudloo Mahalli

    2016-07-01

    Full Text Available Introduction Oolitic iron formations are sedimentary rocks with >5 vol.% oolites and >15 wt.% iron, corresponding to 21.4 wt.% Fe2O3 (Young, 1989; Petranek and Van Houten, 1997; Mucke and Farshad, 2005. In Iran, new iron oolite-bearing members have been identified in the Lashkarak Formation (lower-middle Ordovician in the Abarsej, Dehmola and Simehkuh sections, eastern Alborz (Ghobadi Pour et al., 2011. At present, the mineralogy and geochemistry of these members are not known. Consequently, research reported here was conducted to reveal the mineralogical and geochemical characteristics of Ordovician oolitic iron formationmembers and to discuss their genesis and economic importance. Materials and Analyses Field geology and sampling was carried out to collect 25 samples from the ooliticiron formation members in the Abarsej, Dehmola and Simehkuh section in eastern Alborz. Samples were prepared for polished-thin sections (n=10, XRD analysis (n=15. Whole-rock chemical analysis (n=15 by XRF for major elements and by ICP-ES for trace elements was performed by laboratories at the SarCheshmeh copper mine complex, Kerman, Iran. One sample was analyzed by SEM at the Wales Museum, UK. Results Microscopic studies show that the oolitic iron formation members are hosted by carbonate argillite rocks. They are mainly composed of oolites rather than pisoliths (small bodies somewhat larger and more irregular than oolites, whereas oolites have mainly ellipsoidal forms and locally spherical shapes. Most (6 oolites show banding with a central core. Simple oolites without a core are scarce. Mineralogically, oolites are mainly chamositic and hematitic in composition; goethite, pyrite and glauconite occur in traces and siderite is absent. Quartz, calcite and zircon are accessory minerals which are present in the groundmass. Geochemically, TFeO % of the oolitic iron formation horizons ranges from 8 to 48 % with an average of 21%. The CaO content ranges from 2 to 37% and

  3. Features of the mental status of patients with community-acquired pneumonia, combined with a chronic pathology of the hepatobiliary system of non-viral genesis

    Directory of Open Access Journals (Sweden)

    Razumnyi R.V.

    2017-04-01

    Full Text Available The aim was to study the characteristics of mental status of patients with community-acquired pneumonia (CAP, combined with a chronic pathology of the hepatobiliary system of non-viral genesis. We observed 165 patients with CAP in the age of 25-57 years. All patients were divided into two representative groups: I group (68 patients – CAP was comorbid with hepatic steatosis (HS, II group (96 patients with absence of chronic liver disease. To evaluate the psychological profile of patients’ personality we used a standardized multivariate method of personality research and to evaluate the level of anxiety and depression the scale of Spielberger-Hanin test and Beck’s questionnaire were used. Results of the study revealed that 66.2% of patients with CAP, comorbid with HS, declared the formation of psycho-emotional disorders in the form of neurotic reactions to the disease with prevalence of hypochondria, depression, hysterical manifestations with high psychasthenia, trait anxiety and somatic reactions with prevalence of anxiety and emotional instability, lots of somatic complaints, fixation on their own condition with formation of distinctive thinking mode and behavior by the type of "flight into disease". After completion of the standard treatment of patients with CAP, combined with HS, 42,7% of patients had psycho-emotional disorders, which were moderately expressed. Thus, in the complex of treatment and rehabilitative measures in patients with CAP, combined with HS some characteristics of the psychological profile, in the form of psycho-neurotic reaction to the disease should be considered to take optimal corrective actions.

  4. How to get relations between bedrocks and δ13C values of methane and ethane in natural gases?

    International Nuclear Information System (INIS)

    Schuetze, H.; Muehle, K.

    1987-01-01

    Basing on the hypothesis that δ 13 C values of different carbon positions within biomolecules are thermodynamically controlled a model was derived to evaluate δ 13 C values of methane and ethane in the process of thermal genesis from organic matter in bedrocks. To get information about genesis and postgenetic history of a certain natural gas it is necessary to measure both, δ 13 C of methane (C 1 ) and of ethane (C 2 ), too. The isotopic composition of ethane will be nearly unchanged after genesis. In contrast to this the isotopic composition of methane can be changed drastically by molecular diffusion. Therefore δ 13 C of ethane is a well defined indicator of the genesis conditions. (author)

  5. The genesis of breast cancer is a two-step phenomenon. II. Dissociation of two biomarkers in cancer patients from a low risk area of Japan.

    Science.gov (United States)

    Kodama, M; Kodama, T; Murakami, M; Kobayashi, S; Akita, T; Nakamura, Y

    1992-01-01

    The association of dual steroidal disorders with breast cancer, as proposed on the basis of a case-control study in a high risk area of Japan, was tested for its validity in breast cancer patients from a low risk area of Japan. A state of glucocorticoid excess, the first hormonal trait of a breast cancer patient, was assessed using a urinary steroid parameter (a reduction of the androsterone to tetrahydrocortisol ratio by definition), and/or using a physical parameter (an elevation of the waist to hip circumference ratio by definition). Inclination to ovulation failure, the second hormonal trait, was tested using another urinary steroid parameter (a specified disorder of progestin metabolism by definition), and/or a demographic parameter (a reduction in the number of live births by definition). Results obtained are as follows: 1) premenopausal breast cancer patients from a low risk area were found to have the second trait but not the first trait, as tested using 2 parameters for each trait. 2) Postmenopausal cancer patients from a low risk area as well as pre- and post-menopausal cancer patients from a high risk area had both the 2 hormonal traits. 3) There was no discrepancy of results between any 2 test systems with the identification of 2 hormonal traits in 4 cancer patient groups. The significance of the dissociation of 2 hormonal traits, as observed in premenopausal cancer patients from a low risk area, is discussed in favor of the two-step carcinogenesis theory. Possible interaction of heredity and environment in the genesis of breast cancer is also taken into consideration.

  6. Petrography, alteration and genesis of iron mineralization in Roshtkhar

    Directory of Open Access Journals (Sweden)

    Habib Biabangard

    2017-07-01

    Full Text Available Introduction Iron mineralization in Roshtkhar is located in 48 Km east of the city of Roshtkhar and south of the Khorasan Razavi province. It is geologically located in the north east of the Lut block and the Khaf-Bardeskan volcano-plutonic belt. The Khaf-Bardeskan belt is an important metallogenic province since it is a host of valuable ore deposits such as the Kuh-e-Zar Au-Spicularite, the Tanourcheh and the Khaf Iron ore deposits (Karimpour and Malekzadeh Shafaroudi, 2007. Iron and Copper mineralization in this belt are known as the hydrothermal, skarn and IOCG types (Karimpour and Malekzadeh Shafaroudi, 2007. IOCG deposits are a new type of magmatic to hydrothermal mineralization in the continental crust (Hitzman et al., 1992. Precambrian marble, Lower Paleozoic schist and metavolcanics are the oldest rocks of the area. The younger units are Oligocene conglomerate, shale and sandstone, Miocene marl and Quaternary deposits. Iron oxides and Cu sulfides are associated with igneous rocks. Fe and Cu mineralization in Roshtkhar has been subject of a few studies such as Yousefi Surani (2006. This study describes the petrography of the host rocks, ore paragenesis, alteration types, geochemistry, genesis and other features of the Fe and Cu mineralization in the Roshtkhar iron. Methods After detailed field studies and sampling, 30 thin sections and 20 polished sections that were prepared from host rocks and ores were studied by conventional petrographic and mineraloghraphic methods in the geology department of the University of Sistan and Baluchestan. 5 samples from the alteration zones were examined by XRD in the Yamagata University in Japan, and 8 samples from the less altered ones were analyzed by XRF and ICP-OES in the Kharazmi University and the Iranian mineral processing research center (IMPRC in Karaj, respectively. The XRF and ICP-OES data are presented in Table 1. Result and discussion The host rocks of the Roshtkhar Iron deposit are diorite

  7. Subduction-like fluids in the genesis of Mt. Etna magmas: evidence from boron isotopes and fluid mobile elements

    Science.gov (United States)

    Tonarini, Sonia; Armienti, Pietro; D'Orazio, Massimo; Innocenti, Fabrizio

    2001-11-01

    New whole-rock B, Sr, Nd isotope ratios and 87Sr/ 86Sr on clinopyroxenes have been collected to study the enrichment of fluid mobile elements (FMEs) observed in Mt. Etna volcanics. Etna volcano, one of the most active in the world, is located in an extremely complex tectonic context at the boundary between colliding African and European plates. The analytical work focuses on current (1974-1998) and historic (1851-1971) eruptive activity, including some key prehistoric lavas, in order to interpret the secular shift of its geochemical signature to more alkaline compositions. Boron is used as a tool to unravel the role of fluids in the genesis of magmas, revealing far-reaching consequences, beyond the case study of Mt. Etna. Small variations are observed in δ 11B (-3.5 to -8.0‰), 87Sr/ 86Sr (0.70323-0.70370), and 143Nd/ 144Nd (0.51293-0.51287). Moreover, temporal evolution to higher δ 11B and 87Sr/ 86Sr, and to lower 143Nd/ 144Nd, is observed in the current activity, defining a regular trend. Sr isotopic equilibrium between whole-rock and clinopyroxene pairs indicates the successive introduction of three distinct magma types into the Etna plumbing system over time; these are characterized by differing degrees of FME enrichment. In addition, certain lavas exhibit evidence for country rock assimilation, magma-fluid interaction, or magma mixing in the shallow feeding system; at times these processes apparently lowered magmatic δ 11B and/or induced Sr isotopic disequilibrium between whole rock and clinopyroxene. The regular increase of δ 11B values is correlated with Nb/FME and 87Sr/ 86Sr ratios; these correlations are consistent with simple mixing between the mantle source and aqueous fluids derived from nearby Ionian slab. The best fit of Mt. Etna data is obtained using an enriched-MORB mantle source and a fluid phase with δ 11B of about -2‰ and 87Sr/ 86Sr of 0.708. We argue that the slab window generated by differential roll-back of subducting Ionian

  8. Sedimentary mode and reservoir genesis of dual grain banks at the Lower Cambrian Longwangmiao Fm carbonate ramp in the Sichuan Basin

    Directory of Open Access Journals (Sweden)

    Jinhu Du

    2016-11-01

    Full Text Available The gas reservoir of the Lower Cambrian Longwangmiao Fm in the Sichuan Basin is a supergiant integral marine carbonate gas reservoir whose single scale is currently the largest in China. In order to figure out its sedimentary model and reservoir genesis, its geological structures and sedimentary settings and facies were analyzed comprehensively and the lithofacies paleographic map was plotted. It is revealed that the following sedimentary facies are successively developed in the Longwangmiao Fm from West Sichuan to Southeast Chongqing: diamictic tidal flat at the back ramp, grain bank (the upper bank at the inner/shallow ramp – interbank sea (depression, deeper open bay at the platform depression of inner ramp → evaporative lagoon → evaporative tidal flat, tempestite at the middle ramp – barrier beach – mud mound beach (the lower bank, and outer ramp – basin. Accordingly, the specific sedimentary model of dual grain banks in the Longwangmiao Fm carbonate ramp was established as follows. Firstly, in this model, dual grain banks are symmetrically developed with Wanzhou–Yibin platform depression as the axis, on whose dual sides the paleohighs have shallow water bodies with strong energy. Compared with the classical model, the new one has a new upper bank which is developed around the paleohighs covering an area of about 8 × 104 km2. Secondly, the upper bank is large for its paleogeomorphology being located at the highest position with the strongest water energy during deposition. Therefore, it is prone to dolomitization and meteoric dissolution respectively during contemporaneous–penecontemporaneous hot-dry and hot-humid periods, and especially the Caledonian–Early Hercynian denudation wedge out tends to undergo post-supergene multiphase karstification. Therefore, quality reservoirs are more developed on scale. Thirdly, the intergranular pores and vermes moldic pores were dissolved and enlarged due to the multiphase

  9. Cluster analysis of tropical cyclone tracks in the Southern Hemisphere

    Energy Technology Data Exchange (ETDEWEB)

    Ramsay, Hamish A. [Monash University, Monash Weather and Climate, School of Mathematical Sciences, Clayton, VIC (Australia); Camargo, Suzana J.; Kim, Daehyun [Columbia University, Lamont-Doherty Earth Observatory, Palisades, NY (United States)

    2012-08-15

    A probabilistic clustering method is used to describe various aspects of tropical cyclone (TC) tracks in the Southern Hemisphere, for the period 1969-2008. A total of 7 clusters are examined: three in the South Indian Ocean, three in the Australian Region, and one in the South Pacific Ocean. Large-scale environmental variables related to TC genesis in each cluster are explored, including sea surface temperature, low-level relative vorticity, deep-layer vertical wind shear, outgoing longwave radiation, El Nino-Southern Oscillation (ENSO) and the Madden-Julian Oscillation (MJO). Composite maps, constructed 2 days prior to genesis, show some of these to be significant precursors to TC formation - most prominently, westerly wind anomalies equatorward of the main development regions. Clusters are also evaluated with respect to their genesis location, seasonality, mean peak intensity, track duration, landfall location, and intensity at landfall. ENSO is found to play a significant role in modulating annual frequency and mean genesis location in three of the seven clusters (two in the South Indian Ocean and one in the Pacific). The ENSO-modulating effect on genesis frequency is caused primarily by changes in low-level zonal flow between the equator and 10 S, and associated relative vorticity changes in the main development regions. ENSO also has a significant effect on mean genesis location in three clusters, with TCs forming further equatorward (poleward) during El Nino (La Nina) in addition to large shifts in mean longitude. The MJO has a strong influence on TC genesis in all clusters, though the amount modulation is found to be sensitive to the definition of the MJO. (orig.)

  10. Karl Jaspers y la distinción hermenéutica entre entender y explicar en psicopatología. ¿Podríamos reencontrarnos en alguien que padeciera el síndrome de Cotard tipo I?

    OpenAIRE

    Ariso Salgado, José María (UNIR)

    2011-01-01

    Though Karl Jaspers stated in his General Psychopathology that the genesis of delusions is un-understandable rational and empathically, millions of people all over the world and lots of cinema critics seem to have understood in both ways the genesis of the case of Cotard syndrome which appears by the end of the film The Sixth Sense (1999). In this paper, however, I will show that the possibility of understanding rational and empathically the genesis of this case is just unrealisti...

  11. The genesis of the AIDS policy and AIDS Space in Brazil (1981-1989).

    Science.gov (United States)

    Barros, Sandra Garrido de; Vieira-da-Silva, Ligia Maria

    2016-07-21

    To analyze the genesis of the policy for controlling AIDS in Brazil. Socio-historical study (1981-1989), based on Bordieu's genetic sociology, by document analysis, bibliographical review, and in-depth interviews. It consisted of a connection between the analysis of the paths of 33 agents involved in the creation of a social space focusing on AIDS-related issues and the historical possibility conditions of the drafting of a specific policy. AIDS Space is a gathering point for the paths of agents from several social fields (medical, scientific, political, and bureaucratic fields). A specific space for relationships, which enabled the drafting of a policy for controlling the AIDS epidemic, but also a place where the authority to talk about the meaning of the disease, the methods to prevent and treat it was under dispute. The analysis showed how the various structures (democratic administrations in Sao Paulo and at the national level, with public health officers taking important positions) and the lack of a specific therapy contributed to social agents of different ranks and backgrounds to initially set prevention as a priority. The rise of the sanitary movement, the organization of SUS, and the dominance of the medical field at the AIDS Space contributed to foster treatment as a part of the measures to control the epidemic. These conditions allowed drafting a policy based on the integrality of care, by linking prevention and treatment in the following decade, with important participation from state bureaucracy and researchers. Analisar a gênese da política de controle da aids no Brasil. Estudo sócio-histórico (1981-1989), orientado pela sociologia genética de Bourdieu, por meio de análise documental, revisão bibliográfica e entrevistas em profundidade. Consistiu na articulação entre a análise das trajetórias de 33 agentes envolvidos na criação de um espaço social voltado para as questões relativas à aids e as condições históricas de possibilidade

  12. Role of endogenous opioid peptides in the pathogenesis of motion sickness

    International Nuclear Information System (INIS)

    Yasnetsov, V.V.; Il'ina, S.L.; Karsanova, S.K.; Medvedev, O.S.; Mokrousova, A.V.; Sabaev, V.V.; Shashkov, V.A.; Tigranyan, R.A.; Vakulina, O.P

    1986-01-01

    This paper examines the pathogenesis of motion sickness and the role of the various neurochemical systems of the body in the genesis of the condition. It has been shown that the endogenous opioid system participates in the genesis of several pathological processes; this was the motivation for the study. The plasma beta-endorphin level was determined in samples from 19 clinically healthy males. Considering the positive prophylactic and therapeutic effect of naloxone against motion sickness it can be postulated that endogenous opioid peptides participate in the genesis of the vestibulo-autonomic disorders in motion sickness

  13. A double stage dry-wet-fermentation process for a fast and safe digestion of different kinds of organic material

    International Nuclear Information System (INIS)

    Busch, G.; Sieber, M.; Buschmann, J.; Burkhardat, M.

    2009-01-01

    The fermentation of organic material is a four-step-process. It is admissible to merge the first two steps (hydrolysis and acidification) to hydrolysis in general and the last two steps (aceto genesis and methano genesis) to methano genesis. The Brandenburg University of Technology in Cottbus has devised a double stage dry-wet-fermentation process for fast and safe anaerobic degradation. Using these processes, it is possible to decompose different kinds of organic material like renewable material (e. g. maize silage), waste (e. g. household-waste) and industrial material (e. g. glycerine). (Author)

  14. Role of endogenous opioid peptides in the pathogenesis of motion sickness

    Energy Technology Data Exchange (ETDEWEB)

    Yasnetsov, V.V.; Il' ina, S.L.; Karsanova, S.K.; Medvedev, O.S.; Mokrousova, A.V.; Sabaev, V.V.; Shashkov, V.A.; Tigranyan, R.A.; Vakulina, O.P

    1986-01-01

    This paper examines the pathogenesis of motion sickness and the role of the various neurochemical systems of the body in the genesis of the condition. It has been shown that the endogenous opioid system participates in the genesis of several pathological processes; this was the motivation for the study. The plasma beta-endorphin level was determined in samples from 19 clinically healthy males. Considering the positive prophylactic and therapeutic effect of naloxone against motion sickness it can be postulated that endogenous opioid peptides participate in the genesis of the vestibulo-autonomic disorders in motion sickness.

  15. Endocrine distrupting chemicals and human health: The plausibility ...

    African Journals Online (AJOL)

    The plausibility of research results on DDT and reproductive health ... cals in the environment and that human health is inextri- cably linked to the health of .... periods of folliculo-genesis or embryo-genesis that increases risk for adverse effects.

  16. Genesis and formation attribute of military authorities of the Ukrainian сossacks in the XVI – XVIII centuries

    Directory of Open Access Journals (Sweden)

    Nadiya V. Babkova

    2016-02-01

    Full Text Available Here are considered the historical roots of formation and genesis of bunchuks as a part of the whole kleinod complex of Kosh Otamans and Hetmans of the Ukrainian Cossacks. Turkic lexeme «bunchuk» over time has transformed into modern term that is common in Ukrainian culture. Traditionally, the first recorded case of bunchuks’ use by military is associated with the name of the Arab Caliph Abu Bakr and his military battles on the territory of Syria in the 7th century. During the active cross-cultural contacts in the early 13th century, firstly bunchuks became known among the Mongols and later among the Turks. Early Ottomans used them not only as a military sign, but also as a ranking marker of the court official, status present, which raised the social status of a person. From Turks bunchuks were taken by the representatives of the Commonwealth of Poland and at the beginning gave them a meaning of the important symbol of Quarter Army Hetman military power and later, from the middle of the XVII century, of the Polish king. Historical tradition linked the use of bunchuks by Ukrainian Cossacks with the military reforms of Polish monarch Stefan Batory. But modern scientists, studying military history of the Cossacks in the first quarter of the XVII century and using the materials of Polish archives denied this statement and stressed the attention of the Turkish-Tatar vector. For Zaporozhian Cossacks bunchuks were among the attributes of legitimacy or legality of certain actions. In the external design dominated red and black color schemes. National Symbols of early modern Ukrainian state in the middle of the 17th – 18th c., which basis was formed of the attributes of power Zaporozhian Cossacks, recorded bunchuks as personal banners of Hetmans. In order to make the distinction from Zaporozhian Cossacks, Hetmans started using white bunchuks. Historical records kept information about these signs is in the arsenal of Hetman Bohdan Khmelnytsky, Petro

  17. Download this PDF file

    African Journals Online (AJOL)

    2009-12-09

    Dec 9, 2009 ... In modern-day South Africa, many believers base their argument that the state should reinstate the .... in Genesis 9:23–26, which is used to justify slavery. .... starting in Genesis 4 with a brother being murdered and the.

  18. Towards universal health coverage in India: a historical examination of the genesis of Rashtriya Swasthya Bima Yojana - The health insurance scheme for low-income groups.

    Science.gov (United States)

    Virk, A K; Atun, R

    2015-06-01

    Many low- and middle-income countries have introduced State-funded health programmes for vulnerable groups as part of global efforts to universalise health coverage. Similarly, India introduced the Rashtriya Swasthya Bima Yojana (RSBY) in 2008, a publicly-funded national health insurance scheme for people below the poverty line. The authors explore the RSBY's genesis and early development in order to understand its conceptualisation and design principles and thereby establish a baseline for assessing RSBY's performance in the future. Qualitative case study of the RSBY in Delhi. This paper presents results from documentary analysis and semi-structured interviews with senior-level policymakers including the former Labour Minister, central government officials and affiliates, and technical specialists from the World Bank and GIZ. With national priorities focused on broader economic development goals, the RSBY was conceptualised as a social investment in worker productivity and future economic growth in India. Hence, efficiency, competition, and individual choice rather than human needs or egalitarian access were overriding concerns for RSBY designers. This measured approach was strongly reflected in RSBY's financing and benefit structure. Hence, the programme's focus on only the 'poorest' (BPL) among the poor. Similarly, only costlier forms of care, secondary treatments in hospitals, which policymakers felt were more likely to have catastrophic financial consequences for users were covered. This paper highlights the risks of a narrow approach driven by developmental considerations alone. Expanding access and improving financial protection in India and elsewhere requires a more balanced approach and evidence-informed health policies that are guided by local morbidity and health spending patterns. Copyright © 2015 The Royal Society for Public Health. Published by Elsevier Ltd. All rights reserved.

  19. [pH values in the pharynx of the patients presenting with compromised nasal breathing of inflammatory and non-inflammatory genesis concomitant with gastroesophageal reflux disease].

    Science.gov (United States)

    Subbotina, M V; Temnikova, I V; Onuchina, E V

    2015-01-01

    The objective of the present study was to estimate the influence of gastroesophageal reflux disease (GERD) on the pH values in the pharynx and nose. It included 87 patients at the age varying from 18 to 81 years admitted to the Irkutsk-based Railway Clinical Hospital and allocated to four groups. Group 1 was comprised of 25 patients presenting with gastroesophageal reflux disease and chronic rhinosinusitis (CRS), group 2 consisted of 29 patients with CRS in the absence of GERD, group 3 included 22 patients with nasal septum deformations (NSD) and GERD, group 4 included 11 patients with NSD and motor rhinitis without GERD. The control group was formed from 10 volunteers. pH was measured by the contact method with the use ofEkokhim indicator paper. Gastroesophageal reflux disease was diagnosed following the recommendations of the Montreal consensus. It was shown that pH values in the pharynx of the patients with compromised nasal breathing of any origin in combination with GERD were lower than in the absence of GERD and in the healthy volunteers. The study groups did not differ in terms of pH values in the nasal cavity. It is concluded that pH values 4 or lower may serve as the criterion for pharyngo-laryngeal reflux (PLR) concomitant with HERD while pH 5 occurs more frequently in the patients with compromised nasal breathing of any etiology, regardless of the presence or absence of GERD.Disordered nasal breathing of any genesis in the patients presenting with gastroesophageal reflux disease was associated with the feeling of the lump in the throat, congestion of the respiratory tract and the nose, pain in the ears, cardialgia, and irregular heartbeat. It isrecommended to use pH measurements as a criterion for diagnostics of pharyngo-laryngeal reflux in the patients presenting with gastroesophageal reflux disease.

  20. Decline and poleward shift in Indian summer monsoon synoptic activity in a warming climate

    Science.gov (United States)

    Sandeep, S.; Ajayamohan, R. S.; Boos, William R.; Sabin, T. P.; Praveen, V.

    2018-03-01

    Cyclonic atmospheric vortices of varying intensity, collectively known as low-pressure systems (LPS), travel northwest across central India and produce more than half of the precipitation received by that fertile region and its ˜600 million inhabitants. Yet, future changes in LPS activity are poorly understood, due in part to inadequate representation of these storms in current climate models. Using a high-resolution atmospheric general circulation model that realistically simulates the genesis distribution of LPS, here we show that Indian monsoon LPS activity declines about 45% by the late 21st century in simulations of a business-as-usual emission scenario. The distribution of LPS genesis shifts poleward as it weakens, with oceanic genesis decreasing by ˜60% and continental genesis increasing by ˜10%; over land the increase in storm counts is accompanied by a shift toward lower storm wind speeds. The weakening and poleward shift of the genesis distribution in a warmer climate are confirmed and attributed, via a statistical model, to the reduction and poleward shift of low-level absolute vorticity over the monsoon region, which in turn are robust features of most coupled model projections. The poleward shift in LPS activity results in an increased frequency of extreme precipitation events over northern India.

  1. The genesis of ores

    International Nuclear Information System (INIS)

    Brimhall, G.

    1991-01-01

    Human history and technology have been shaped by metals. How did they become concentrated in minable deposits located so conveniently near the earth's surface? The author explains the mechanisms of fluid transport-by magma, water and even air and wind-responsible for the chemical and physical interactions that created bodies of metallic ores throughout geologic history. From their formation to their modification at the surface of the earth, ore deposits are geologically transitory and reflect dynamic processes within the earth as well as atmospheric and climatic influences on hydrologic systems. As highly reactive supracrustal systems, they then serve as geochemical sensors providing a powerful record and set of tracer elements for deducing the history, transport paths and forces operative in the crust

  2. Genesis of social entrepreneurship

    DEFF Research Database (Denmark)

    Kulothungan, Gladius

    of institutions and internal, in terms of motivations and drive in a combination propel the social entrepreneur or the group to create social enterprises. The aim of the investigation is to explore and explain how and why certain individuals/groups create/generate innovative responses/ solutions - understood...... – grants, donations and revenue streams generated by business activities and 4/ they seldom act alone but work within an organizational context. GK has done a number of English and Danish empirical case studies of different social enterprises and beginning the analyses of these....

  3. The Genesis of Capitalism

    DEFF Research Database (Denmark)

    Li, Xing

    2004-01-01

     This paper aims to offer a framework of interpreting the “evolution” of capitalism that is reaching every corner of the world and has achieved greater legitimacy than at any time in human history. It covers an interdisciplinary discussion on the development of market capitalism that has been...... characterized by a dual process: unanticipated origin (cultural and historical) and anticipated progress (political economy). The point of departure of this paper is that although the advancement of market capitalism is a process of societal development involving historical, cultural and religious causes...... (historical, divine, spiritual, miraculous), the establishment of capitalism is less the result of a force for cultural and economic dynamism than the realization of a political project. In other words, from being an enterprise within defined geographical boundaries to becoming a global project is first...

  4. Ontogenic retinal changes in three ecologically distinct elopomorph fishes (Elopomorpha:Teleostei) correlate with light environment and behavior.

    Science.gov (United States)

    Taylor, Scott M; Loew, Ellis R; Grace, Michael S

    2015-01-01

    Unlike the mammalian retina, the teleost fish retina undergoes persistent neurogenesis from intrinsic stem cells. In marine teleosts, most cone photoreceptor genesis occurs early in the embryonic and larval stages, and rods are added primarily during and after metamorphosis. This study demonstrates a developmental paradigm in elopomorph fishes in which retinas are rod-dominated in larvae, but undergo periods of later cone genesis. Retinal characteristics were compared at different developmental stages among three ecologically distinct elopomorph fishes-ladyfish (Elops saurus), bonefish (Albula vulpes), and speckled worm eel (Myrophis punctatus). The objectives were to improve our understanding of (1) the developmental strategy in the elopomorph retina, (2) the functional architecture of the retina as it relates to ecology, and (3) how the light environment influences photoreceptor genesis. Photoreceptor morphologies, distributions, and spectral absorption were studied at larval, juvenile, and adult stages. Premetamorphic retinas in all three species are rod-dominated, but the retinas of these species undergo dramatic change over the course of development, resulting in juvenile and adult retinal characteristics that correlate closely with ecology. Adult E. saurus has high rod densities, grouped photoreceptors, a reflective tapetum, and longer-wavelength photopigments, supporting vision in turbid, low-light conditions. Adult A. vulpes has high cone densities, low rod densities, and shorter-wavelength photopigments, supporting diurnal vision in shallow, clear water. M. punctatus loses cones during metamorphosis, develops new cones after settlement, and maintains high rod but low cone densities, supporting primarily nocturnal vision. M. punctatus secondary cone genesis occurs rapidly throughout the retina, suggesting a novel mechanism of vertebrate photoreceptor genesis. Finally, in postsettlement M. punctatus, the continuous presence or absence of visible light

  5. Geometry of Majorana neutrino and new symmetries

    CERN Document Server

    Volkov, G G

    2006-01-01

    Experimental observation of Majorana fermion matter gives a new impetus to the understanding of the Lorentz symmetry and its extension, the geometrical properties of the ambient space-time structure, matter--antimatter symmetry and some new ways to understand the baryo-genesis problem in cosmology. Based on the primordial Majorana fermion matter assumption, we discuss a possibility to solve the baryo-genesis problem through the the Majorana-Diraco genesis in which we have a chance to understand creation of Q(em) charge and its conservation in our D=1+3 Universe after the Big Bang. In the Majorana-Diraco genesis approach there appears a possibility to check the proton and electron non-stability on the very low energy scale. In particle physics and in our space-time geometry, the Majorana nature of the neutrino can be related to new types of symmetries which are lying beyond the binary Cartan-Killing-Lie algebras/superalgebras. This can just support a conjecture about the non-completeness of the SM in terms of ...

  6. S- and Sr-isotopic compositions in barite-silica chimney from the Franklin Seamount, Woodlark Basin, Papua New Guinea: constraints on genesis and temporal variability of hydrothermal fluid

    Science.gov (United States)

    Ray, Durbar; Banerjee, Ranadip; Balakrishnan, S.; Paropkari, Anil L.; Mukhopadhyay, Subir

    2017-07-01

    Isotopic ratios of strontium and sulfur in six layers across a horizontal section of a hydrothermal barite-silica chimney from Franklin Seamount of western Woodlark Basin have been investigated. Sr-isotopic ratios in barite samples (87Sr/86Sr = 0.70478-0.70493) are less radiogenic than seawater (87Sr/86Sr = 0.70917) indicating that substantial leaching of sub-seafloor magma was involved in the genesis of hydrothermal fluid. The SO2 of magma likely contributed a considerable amount of lighter S-isotope in fluid and responsible for the formation of barite, which is isotopically lighter (δ34S = 19.4-20.5 ‰) than modern seawater (δ34S 21 ‰). The systematic changes in isotopic compositions across the chimney wall suggest temporal changes in the mode of mineral formation during the growth of the chimney. Enrichment of heavy S- and Sr-isotopes (δ34S = 20.58 ‰; 87Sr/86Sr = 0.70493) in the outermost periphery of the chimney indicates that, at the initial stage of chimney development, there was a significant contribution of seawater sulfate during barite mineralization. Thereafter, thickening of chimney wall occurred due to precipitation of fluid carrying more magmatic components relative to seawater. This led to a gradual enrichment of lighter isotopes (δ34S = 20.42-19.48 ‰; 87Sr/86Sr = 0.70491-0.704787) toward the inner portion of the chimney wall. In contrast, the innermost layer surrounding the fluid conduit is characterized by heavier and more radiogenic isotopes (δ34S = 20.3 ‰; 87Sr/86Sr = 0.7049). This suggests there was increasing influence of percolating seawater on the mineral paragenesis at the waning phase of the chimney development.

  7. Development and characterization of a hydrogen peroxide-resistant cholangiocyte cell line: A novel model of oxidative stress-related cholangiocarcinoma genesis

    Energy Technology Data Exchange (ETDEWEB)

    Thanan, Raynoo [Department of Biochemistry, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002 (Thailand); Liver Fluke and Cholangiocarcinoma Research Center, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002 (Thailand); Techasen, Anchalee [Liver Fluke and Cholangiocarcinoma Research Center, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002 (Thailand); Faculty of Associated Medical Science, Khon Kaen University, Khon Kaen 40002 (Thailand); Hou, Bo [Department of Environmental and Molecular Medicine, Mie University Graduate School of Medicine, Tsu, Mie 514-8507 (Japan); Jamnongkan, Wassana; Armartmuntree, Napat [Department of Biochemistry, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002 (Thailand); Liver Fluke and Cholangiocarcinoma Research Center, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002 (Thailand); Yongvanit, Puangrat, E-mail: puangrat@kku.ac.th [Department of Biochemistry, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002 (Thailand); Liver Fluke and Cholangiocarcinoma Research Center, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002 (Thailand); Murata, Mariko, E-mail: mmurata@doc.medic.mie-u.ac.jp [Department of Environmental and Molecular Medicine, Mie University Graduate School of Medicine, Tsu, Mie 514-8507 (Japan)

    2015-08-14

    Oxidative stress is a cause of inflammation–related diseases, including cancers. Cholangiocarcinoma is a liver cancer with bile duct epithelial cell phenotypes. Our previous studies in animal and human models indicated that oxidative stress is a major cause of cholangiocarcinoma development. Hydrogen peroxide (H{sub 2}O{sub 2}) can generate hydroxyl radicals, which damage lipids, proteins, and nucleic acids, leading to cell death. However, some cells can survive by adapting to oxidative stress conditions, and selective clonal expansion of these resistant cells would be involved in oxidative stress-related carcinogenesis. The present study aimed to establish H{sub 2}O{sub 2}-resistant cell line from an immortal cholangiocyte cell line (MMNK1) by chronic treatment with low-concentration H{sub 2}O{sub 2} (25 μM). After 72 days of induction, H{sub 2}O{sub 2}-resistant cell lines (ox-MMNK1-L) were obtained. The ox-MMNK1-L cell line showed H{sub 2}O{sub 2}-resistant properties, increasing the expression of the anti-oxidant genes catalase (CAT), superoxide dismutase-1 (SOD1), superoxide dismutase-2 (SOD2), and superoxide dismutase-3 (SOD3) and the enzyme activities of CAT and intracellular SODs. Furthermore, the resistant cells showed increased expression levels of an epigenetics-related gene, DNA methyltransferase-1 (DNMT1), when compared to the parental cells. Interestingly, the ox-MMNK1-L cell line had a significantly higher cell proliferation rate than the MMNK1 normal cell line. Moreover, ox-MMNK1-L cells showed pseudopodia formation and the loss of cell-to-cell adhesion (multi-layers) under additional oxidative stress (100 μM H{sub 2}O{sub 2}). These findings suggest that H{sub 2}O{sub 2}-resistant cells can be used as a model of oxidative stress-related cholangiocarcinoma genesis through molecular changes such as alteration of gene expression and epigenetic changes. - Highlights: • An H{sub 2}O{sub 2}-resistant ox-MMNK1-L cells was established from

  8. Respek vir die lewe en die doodstraf volgens die perspektief van ...

    African Journals Online (AJOL)

    There are different views on the application of Genesis 9:5-6 in the debate on the value of life and the death penalty. In postmodern society it is considered inhumane to execute persons who committed murder. In this article different views are discussed and it is suggested that, according to Genesis 9:5, respect for life is ...

  9. Roentgenologic characteristic of 7 group contingent of dispensary registration

    International Nuclear Information System (INIS)

    Derzhavin, V.I.; Nalivajko, N.N.; Kozlova, L.N.; Petrik, R.N.

    1984-01-01

    9694 persons of 7 group contingent of dispensary registration were examined. Roentgenologic study of posttuberculous changes of 7 group contingent of dispensary registration showed that in people of 7-A subgroup prevail processes of secondary genesis (79.4%) and in people of 7-B subgroup - of primary genesis (55.8%). Consequences of secondary tuberculosis are most recurring

  10. Prospecting and exploration of the Key Lake uranium deposits, Saskatchewan, Canada

    International Nuclear Information System (INIS)

    Tan, B.H.

    1980-01-01

    The research activities which led to the detection of the Key Lake deposit and their model character for uranium prospecting in this area are discussed. The genesis of the ores and the surrounding rocks are described, and the possible genesis of the deposit is discussed on the basis of the present state of knowledge. (HP) [de

  11. Action antiadipogenic of weak magnetic fields: A model for the study of the etiology of the semicircular lipoatrophy in media occupational; Accion antiadipogenica de campos magneticos debiles: un modelo para el estudio de la etiologia de la lipoatrofia semicircular en medios ocupacionales

    Energy Technology Data Exchange (ETDEWEB)

    Martinez Pascual, M. A.; Paino Belarrinaga, C. L.; Trillo ruiz, M. A.; Ubeda Maeso, A.

    2013-07-01

    Although several studies have suggested a possible association between exposure to environmental magnetic fields of industrial frequency and semicircular lipoatrophy, a mechanism that justifies the potential action of these fields magnetic on the adipo genesis has not been identified. The study investigated the in vitro action of a field weak magnetic on the adipo genesis of human adipose tissue-derived stem cells. (Author)

  12. Study Of The Rupture Process Of The 2015 Mw7.8 Izu-Bonin Earthquake And Its Implication To Deep-Focus Earthquake Genesis.

    Science.gov (United States)

    Jian, P. R.; Hung, S. H.; Meng, L.

    2015-12-01

    length of 15-20 km and weaker radiated energy. The overall rupture speed is about 1.5-2 km/s. As it rarely struck the area close to the outer periphery of the slab under the condition of relatively high-temperature and downdip extension, thermally-induced shear instability may play an important role in the genesis of this deep-focus earthquake.

  13. Future changes in tropical cyclone activity projected by multi-physics and multi-SST ensemble experiments using the 60-km-mesh MRI-AGCM

    Energy Technology Data Exchange (ETDEWEB)

    Murakami, Hiroyuki [Japan Agency for Marine-Earth Science and Technology (JAMSTEC)/Meteorological Research Institute (MRI), Tsukuba, Ibaraki (Japan); University of Hawaii at Manoa, International Pacific Research Center, School of Ocean and Earth Science and Technology, Honolulu, Hawaii (United States); Mizuta, Ryo; Shindo, Eiki [Meteorological Research Institute (MRI), Climate Research Department, Tsukuba, Ibaraki (Japan)

    2012-11-15

    Uncertainties in projected future changes in tropical cyclone (TC) activity are investigated using future (2075-2099) ensemble projections of global warming under the Intergovernmental Panel on Climate Change (IPCC) A1B scenario. Twelve ensemble experiments are performed using three different cumulus convection schemes and four different assumptions for prescribed future sea surface temperatures (SSTs). All ensemble experiments consistently project significant reductions in global and hemispheric TC genesis numbers as well as reductions in TC frequency of occurrence (TCF) and TC genesis frequency (TGF) in the western North Pacific, South Indian Ocean, and South Pacific Ocean. TCF and TGF are projected to increase over the central Pacific which is consistent with the findings of Li et al. (2010). Inter-experimental variations of projected future changes in TGF and TC genesis number are caused mainly by differences in large-scale dynamical parameters and SST anomalies. Thermodynamic parameters are of secondary importance for variations in TGF and TC genesis number. These results imply that differences in SST spatial patterns can cause substantial variations and uncertainties in projected future changes of TGF and TC numbers at ocean-basin scales. (orig.)

  14. Petrological and geochemical features of the early Paleozoic granitic gneisses and iron ores in the Tianhu iron deposit, Eastern Tianshan, NW China: Implications for ore genesis

    Science.gov (United States)

    Zheng, Jiahao; Mao, Jingwen; Yang, Fuquan; Chai, Fengmei; Shen, Ping

    2017-08-01

    This paper reports whole-rock geochemical, zircon U-Pb and Hf isotopic data for ore-hosted granitic gneisses, mineral compositions of oxides, and sulfur isotopic data for sulfides in iron ores from the Tianhu deposit, central part of the Eastern Tianshan. Our results can provide crucial constraints on the genesis of granitic gneisses and early Paleozoic tectonic setting of the Eastern Tianshan. LA-ICP-MS U-Pb dating on magmatic zircons yielded weighted mean 206Pb/238U ages of 463 to 438 Ma, interpreted as the crystallization ages of the granitic protoliths and the formation ages of the Tianhu Group. Zircon U-Pb age of ore-hosted granitic gneiss (ca. 459 Ma) can provide reliable constrains on upper limit for iron mineralization age in the Tianhu deposit. Geochemical characteristics suggest that the protoliths of the Tianhu granitic gneisses are metaluminous to weakly peraluminous high-K calc-alkaline granitic rocks, exhibiting typical subduction-related features such as strong enrichment in LREE and LILE and depletion in HFSE. Zircon Hf isotopic compositions show a positive trend from 463 to 438 Ma, indicating that 460 Ma magmas came from both ancient and juvenile sources, whereas 438 Ma magmas involved more juvenile material. Some early Paleozoic granitoids were recently identified in the Eastern Tianshan with the ages between ca. 475 and ca. 425 Ma. The formation of these early Paleozoic granitoids was in response to subduction processes, suggesting that subduction of Junggar Ocean probably began in the Early Ordovician and lasted until Late Silurian. Pyrite and pyrrhotite in iron ores have δ34SCDT values from + 4.6 to + 15.7‰, which are consistent with the marine source, but inconsistent with the magmatic source or those involved evaporites in skarn iron deposit. Geological, geochemical, and isotopic data suggest that the Tianhu iron ores were formed by volcano-sedimentary processes in a subduction environment during the early Paleozoic time, and Tianhu is a

  15. Apollo 15 mare units and their petrogenesis

    International Nuclear Information System (INIS)

    Binder, A.A.

    1985-01-01

    Samples from 12 different mare sites were identified and classified among the Apollo 15 samples. The genesis of the Apollo 15 mare units is summarized given the general model of mare basalt source regions and of more basalt genesis derived from a synthesis of the major oxide/major mineral, compatible siderophile, and incompatible trace element data and isotopic ratios of the Rb/Sr and Sm/Nd systems

  16. Os nitritos são importantes na gênese do adenocarcinoma associado ao esôfago de Barrett? Are the nitrites important in a genesis of the adenocarcinoma associated to the Barrett esophagus?

    Directory of Open Access Journals (Sweden)

    Sergio Ferreira Módena

    2008-09-01

    Full Text Available RACIONAL: O esôfago de Barrett é complicação do refluxo gastroesofágico e predispõe ao surgimento do adenocarcinoma, sendo que vários fatores têm sido relacionados à sua etiopatogenia. OBJETIVO: Analisar o modelo experimental de refluxo duodenogastroesofágico e a ingestão de solução de nitrito de sódio na gênese do adenocarcinoma associado ao esôfago de Barrett. MÉTODOS: Sessenta ratos machos Wistar foram divididos em quatro grupos, com 20 animais controles não operados (10 animais ingeriram somente água e 10 água mais solução de nitrito de sódio e 40 animais submetidos à anastomose duodenogastroesofágica látero-lateral (20 animais ingeriram somente água e 20 animais ingeriram água mais solução de nitrito de sódio. A ocorrência de esofagite, metaplasia, displasia, esôfago de Barrett e adenocarcinoma associado foram analisados. A classificação de Viena para displasia e adenocarcinoma foi empregada na análise dos resultados. RESULTADOS: Após 42 semanas de observação, nos animais operados sem ingestão de nitritos o esôfago de Barrett foi registrado em 26,3% (5/19, enquanto no grupo operado associado à ingestão de nitritos, foi encontrado em 72,3% (13/18 dos animais, sendo que neste grupo também foi encontrado seis adenocarcinomas (33,3%. Nenhum animal não operado apresentou o esôfago de Barrett. As categorias 2, 3 e 5 da classificação de Viena somente foram encontradas nos animais operados que ingeriram nitrito de sódio (66,7%. CONCLUSÃO: A ingestão de nitrito de sódio associado ao refluxo duodenogastroesofágico têm importante participação na gênese do adenocarcinoma associado ao esôfago de Barrett.BACKGROUND: Barrett's esophagus is a complication of gastroesophageal reflux and predisposes to adenocarcinoma of the esophagogastric transition and several factors have been related to its pathogenesis. AIM: To evaluated the genesis of adenocarcinoma associated with Barrett's esophagus in an

  17. Towards Genesis or the Grave

    DEFF Research Database (Denmark)

    Hansen, Sune Welling

    The paper outlines a theoretical framework for understanding reform-related opportunism in connection with current local government mergers in Denmark. The chain of reasoning is based on a local government version of the political business cycle. Where this model predicts cyclical financial patte...... and group level). This is achieved with the aid of insights from collective action theory.......The paper outlines a theoretical framework for understanding reform-related opportunism in connection with current local government mergers in Denmark. The chain of reasoning is based on a local government version of the political business cycle. Where this model predicts cyclical financial...... patterns on reversible financial expenditures within each election period, the developed argument on local government mergers posits a pattern on non-reversible expenditures in the immediate years preceding them. The paper utilizes a theory-testing design with explanatory factors on two levels (individual...

  18. Quantum cosmology - science of Genesis

    International Nuclear Information System (INIS)

    Padmanabhan, Thanu

    1987-01-01

    Quantum cosmology, the marriage between the theories of the microscopic and macroscopic Universe, is examined in an attempt to explain the birth of the Universe in the 'big bang'. A quantum cosmological model of the Universe does not exist, but a rough approximation, or 'poor man's' version of quantum cosmology has been developed. The idea is to combine the theory of quantum mechanics with the classical cosmological solutions to obtain a quantum mechanical version of cosmology. Such a model of quantum cosmology is described -here the quantum universe behaves like a hydrogen atom with the Planck length replacing the Bohr radius. Properties of quantum cosmologies and the significance of the Planck length are both discussed. (UK)

  19. The genesis of general relativity

    CERN Document Server

    Norton, John; Renn, Jürgen; Sauer, Tilman; Stachel, John

    2007-01-01

    This four-volume work represents the most comprehensive documentation and study of the creation of general relativity; one of the fundamental physical theories of the 20th century. It comprises key sources from Einstein and others who from the late 19th to the early 20th century contributed to this monumental development. Some of these sources are presented here in translation for the first time. Einstein’s famous Zurich notebook, which documents the pivotal steps toward general relativity, is reproduced here for the first time and transcribed in its entirety. The volumes offer detailed commentaries and analyses of these sources that are based on a close reading of these documents supplemented by interpretations by the leading historians of relativity. All in all, the facets of this work, based on more than a decade of research, combine to constitute one of the most in-depth studies of a scientific revolution ever written.

  20. Genesis of ZnO nanoparticles

    International Nuclear Information System (INIS)

    Silva, M.N. da; Pulcinelli, S.H.; Santilli, C.V.

    2014-01-01

    Zinc oxide is a semiconductor with direct band gap, of 3,37 eV, and high excitons energy (60 MeV). The main key for comprehension of the mechanisms that rules particle formation, lay in a full understanding of the first step of formation and growing of this nanoparticle. Zinc oxide nanoparticle were prepared through modification in the method first proposed by Spanhel & Anderson, the characterization techniques were followed by UV-Vis spectroscopy and small angle X ray scattering (SAXS). The results have shown that in the reaction first step we have nanoparticle size between 0,32 e 2,0 nm, whose growing steps can be described by Diffusion-limited cluster-cluster aggregation (DLCA), where self-similar primary structures aggregate keeping the initial morphology. (author)

  1. Genesis and servitudes of nuclear

    International Nuclear Information System (INIS)

    Debeir, Jean-Claude; Deleage, Jean-Paul; Hemery, Daniel

    2011-01-01

    This article is a chapter of a book published by the authors after the catastrophe of Chernobyl. They first propose a history of nuclear in four main stages: first, from the atom of physicists to the bomb (1932-1942), second, the bomb, and the American policy of atomic monopoly and its failure (1940-1956), third, the beginnings of the nuclear energy (1952-1969), and the recession (1974-?). Then, they discuss electro-nuclear energy as the last energetic component of the capital accumulation regime based on mass consumption and issued the great depression of the 1930's. In the next part, they identify some historical peculiarities of nuclear, notably with an emergence of discontinuities in the energetic process, the power to the science, the joining between the energy system and the war system, the nationalisation of energy, and the trend in capital valorisation and restructuring

  2. Genesis of a bad idea

    Science.gov (United States)

    Carlowicz, Michael

    According to an article in Business Week (June 10), Macmillan/McGraw-Hill Inc. has agreed to custom-publish a version of its fourth-grade textbook Changing Earth in order to omit a chapter entitled “Birth of Earth.” Parents in the Cobb County, Georgia, school district complained that since the chapter does not include creationism as a theory for the origin of the universe and of Earth, the entire discussion ought to be left out.According to McGraw-Hill, customizing its textbooks is good business. Changing Earth and other such books are designed to allow teachers to build their own programs; the company is willing to customize texts because it does not want to dictate curricula, and it tries to meet demands of school districts. Business Week noted that the theory of evolution still is taught in the sixth and eighth grades, as well as high school, in Cobb County. Changing Earth also contains references to evolution in other chapters besides the one being deleted.

  3. Towards Genesis or the Grave

    DEFF Research Database (Denmark)

    Hansen, Sune Welling

    -beens can lead to decidedly myopic and short-sighted behavior in spite of its longer-term consequences. So much for actor incentives! On the institutional side, the incumbent government has, in contrast to its forty-year-old likewise bourgeois predecessor, been all too aware of these ‘perverse' incentives......' financial behavior stand out in the period leading up to the second local government reform - and if so then why? As will be explicated in later chapters, the measuring rod for ‘standing out' will be both temporal (compared to the authorities' financial dispositions in previous years) and spatial (compared......' financial dispositions as liquidity, near-liquid assets (sales of buildings, land and so forth), expenditures on buildings and probably also operations, borrowing, public utilities and expenditures on personnel....

  4. Osteoarthritis: the genesis of pain.

    Science.gov (United States)

    Fu, Kai; Robbins, Sarah R; McDougall, Jason J

    2018-05-01

    OA is a painful joint disease that predominantly affects the elderly. Pain is the primary symptom of OA, and it can present as either intermittent or constant. OA pain mechanisms are complex and have only recently been determined. Both peripheral and central processes are involved in creating the OA pain experience, making targeted therapy problematic. Nociceptive, inflammatory and neuropathic pains are all known to occur in OA, but to varying degrees in a patient- and time-specific manner. A better understanding of these multifactorial components of OA pain will lead to the development of more effective and safer pain treatments.

  5. The Genesis 2.0 Project

    CERN Multimedia

    Andersen, Kurt

    2010-01-01

    "Compared with the market-driven, killer-app insta-culture of the Digital Age, the new Large Hadron Collider exists in a near-magical realm, a $9 billion cathedral of science that is apparently, in any practical sense, useless. Exploring its whizbang machinery, deep underground, Kurt Andersen probes the collider's brush with disaster last year - and the secrets it may soon unlock" (10 pages)

  6. Modelling the Genesis and Evolution

    DEFF Research Database (Denmark)

    Hjelholt, Morten; Damsgaard, Jan

    Over the last three decades, EU regulation of the internal market has become highly pervasive, affecting practically all the domains of European citizens’ lives. Many studies have focused on understanding the process and causes of regulatory reform. However, these have typically been small...

  7. Genesis of enterprise financial security

    Directory of Open Access Journals (Sweden)

    Davydenko N. M.

    2015-05-01

    Full Text Available The article analyzes the scientific approaches to the definition of «financial security of entities», advantages and disadvantages of these approaches are highlighted. The own definition of financial security of entities is given. The composition of elements of enterprise financial security and principles of its provision are defined. Тhe role of individual elements of financial security to ensure high efficiency operation and development of enterprises is significant and has a direct impact on their solvency, liquidity and profitability.

  8. Genesis of non-codified customs

    Directory of Open Access Journals (Sweden)

    Atefeh Roohi Kargar

    2017-12-01

    Full Text Available The study of what is called “customary law” and “non-written rules” is always faced with ambiguity due to the lack of written resources. The reason for emphasizing the role of custom and applying the words on their customary meanings was to re-focus on this rich source of rights, which is far from sights. By reviewing the Articles, books and documentary data, we tried to look again at the status of unwritten conventions, legal rules and legal principles that could be interpreted as legal norms. If written or assigned to a bunch or a material to them, along with other laws they can be a good complement. This paper intends to review the role of custom and habit in concluding contracts by reviewing past comparative law studies and helping out the role of custom and unwritten rights. Besides, it intends to unify the material of Arts. 220, 225 and other Arts. of civil law of the parties to the awareness of the custom, because ignorance of the customary is not like ignorance of the law.

  9. Topical review: sleep bruxism and the role of peripheral sensory influences.

    Science.gov (United States)

    Kato, Takafumi; Thie, Norman M; Huynh, Nelly; Miyawaki, Shouichi; Lavigne, Gilles J

    2003-01-01

    Sleep bruxism (SB) is an unusual orofacial movement described as a parafunction in dentistry and as a parasomnia in sleep medicine. Since several peripheral influences could be involved in sleep-wake regulation and the genesis of rhythmic jaw movements, the authors have reviewed the relevant literature to facilitate understanding of mechanisms possibly involved in SB genesis. Various animal and human studies indicate that during either wakefulness or anesthesia, orofacial sensory inputs (e.g., from periodontium, mucosa, and muscle) could influence jaw muscle activity. However, the role of these sensory inputs in jaw motor activity during sleep is unclear. Interestingly, during sleep, the jaw is usually open due to motor suppression; tooth contact most likely occurs in association with sleep arousal. Recent physiologic evidence supports an association between sleep arousal and SB; a sequential change from autonomic (cardiac) and brain cortical activities precede SB-related jaw motor activity. This suggests that the central and/or autonomic nervous systems, rather than peripheral sensory factors, have a dominant role in SB genesis. However, some peripheral sensory factors may exert an influence on SB through their interaction with sleep-wake mechanisms. The intent of this review is to integrate various physiologic concepts in order to better understand the mechanisms underlying the genesis of SB.

  10. The Impacts of Satellite Remotely Sensed Winds and Total Precipitable Vapour in WRF Tropical Cyclone Track Forecasts

    Directory of Open Access Journals (Sweden)

    Diandong Ren

    2016-01-01

    Full Text Available This study assesses the impact assimilating the scatterometer near-surface wind observations and total precipitable water from the SSMI, into WRF on genesis and track forecasting of four tropical cyclones (TCs. These TCs are selected to be representative of different intensity categories and basins. Impact is via a series of data denial experiments that systematically exclude the remote sensed information. Compared with the control case, in which only the final analysis atmospheric variables are used to initialize and provide the lateral boundary conditions, the data assimilation runs performed consistently better, but with very different skill levels for the different TCs. Eliassen-Palm flux analyses are employed. It is confirmed that if a polar orbital satellite footprint passes over the TC’s critical genesis region, the forecast will profit most from assimilating the remotely sensed information. If the critical genesis region lies within an interorbital gap then, regardless of how strong the TC later becomes (e.g., Katrina 2005, the improvement from assimilating near-surface winds and total precipitable water in the model prediction is severely limited. This underpins the need for a synergy of data from different scatterometers/radiometers. Other approaches are suggested to improve the accuracy in the prediction of TC genesis and tracks.

  11. Flux and genesis of CO2 degassing from volcanic-geothermal fields of Gulu-Yadong rift in the Lhasa terrane, South Tibet: Constraints on characteristics of deep carbon cycle in the India-Asia continent subduction zone

    Science.gov (United States)

    Zhang, Lihong; Guo, Zhengfu; Sano, Yuji; Zhang, Maoliang; Sun, Yutao; Cheng, Zhihui; Yang, Tsanyao Frank

    2017-11-01

    Gulu-Yadong rift (GYR) is the longest extensional, NE-SW-trending rift in the Himalayas and Lhasa terrane of South Tibet. Many volcanic-geothermal fields (VGFs), which comprise intense hot springs, steaming fissures, geysers and soil micro-seepage, are distributed in the GYR, making it ideal area for studying deep carbon emissions in the India-Asia continent subduction zone. As for the northern segment of GYR in the Lhasa terrane, its total flux and genesis of CO2 emissions are poorly understood. Following accumulation chamber method, soil CO2 flux survey has been carried out in VGFs (i.e., Jidaguo, Ningzhong, Sanglai, Tuoma and Yuzhai from south to north) of the northern segment of GYR. Total soil CO2 output of the northern GYR is about 1.50 × 107 t a-1, which is attributed to biogenic and volcanic-geothermal source. Geochemical characteristics of the volcanic-geothermal gases (including CO2 and He) of the northern GYR indicate their significant mantle-derived affinities. Combined with previous petrogeochemical and geophysical data, our He-C isotope modeling calculation results show that (1) excess mantle-derived 3He reflects degassing of volatiles related with partial melts from enriched mantle wedge induced by northward subduction of the Indian lithosphere, and (2) the crust-mantle interaction can provide continuous heat and materials for the overlying volcanic-geothermal system, in which magma-derived volatiles are inferred to experience significant crustal contamination during their migration to the surface.

  12. LA TOUR DE BABEL ET LA PIERRE DE BETHEL: LES MÉFAITS DU MULTILINGUISME ET LES BIENFAITS DE L`INTÉRIORITÉ

    Directory of Open Access Journals (Sweden)

    Acad. Baudouin DECHARNEUX

    2015-11-01

    Full Text Available In our recent publications we have discussed and argued our point on the problem of the sacred places in the Hebrew religion. In the following lines we are going to reflect on two texts in the Genesis, which we propose to read in a synoptic manner: t he Tower of Babel (Genesis 11, 2 - 9 and the dream of Jacob (Genesis 28, 10 - 22. The two narratives seem in fact constructed so as to contrast two ways of relating to the Word: using it so as to build for material purposes and receiving it for understanding its spiritual purposes. The tension dramatized by the two texts seems to reveal a complex theology of the Word, which, being undoubtedly grafted on archaic stories, attests to a will for a conceptual unification typical of a cosmological monotheism.

  13. Assessing phylogenetic accuracy : a simulation study

    OpenAIRE

    Heijerman, T.

    1995-01-01

    A simulation model of phylogeny, called GENESIS, was developed to evaluate and to estimate the qualities of various numerical taxonomic procedures. The model produces sets of imaginary species with known character state distributions and with known phylogenies. The model can be made to produce these species and their phylogenies under different evolutionary conditions.

    Within GENESIS, there are two mathematical models that describe the diversification of the number of taxa. T...

  14. Biogas recuperation in sanitary landfills; Recuperacao de biogas em aterros sanitarios

    Energy Technology Data Exchange (ETDEWEB)

    Lima, Luiz Mario Queiroz [Companhia Paulista de Forca e Luz (CPFL), Campinas, SP (Brazil)

    1988-12-31

    This work shoes a retrospective about recovering biogas activity in sanitary landfill, where in the genesis of methane is emphasized. Also, a conceptual review was made and discussed focusing the technological aspects of the landfill methods. Further, two important aspects of the genesis of methane were discussed: the enhancement mechanisms for acceleration of the formation of methane and the production of biological input from leachate in landfill. (author) 36 refs., 3 figs.

  15. Idiopatiske skolioser

    DEFF Research Database (Denmark)

    Andersen, M O; Andersen, G R; Christensen, S B

    1993-01-01

    The article summarizes the current theories on the aetiology, natural history, diagnosis and treatment of adolescent idiopathic scoliosis. Much remains unknown concerning the genesis of scoliosis. The current treatment with bracing or spinal fusion is effective.......The article summarizes the current theories on the aetiology, natural history, diagnosis and treatment of adolescent idiopathic scoliosis. Much remains unknown concerning the genesis of scoliosis. The current treatment with bracing or spinal fusion is effective....

  16. Modulation of the intraseasonal Indo-western Pacific convection oscillation to tropical cyclogenesis location and frequency over the Indo-western North Pacific during boreal extended summer

    Science.gov (United States)

    Wang, Qiuyun; Li, Jianping; Li, Yanjie; Zhang, Jingwen

    2017-04-01

    The influence of the intraseasonal Indo-western Pacific convection oscillation (IPCO) on the tropical cyclone (TC) genesis location and frequency over the Indo-western North Pacific during the boreal extended summer (May-October) is explored in this paper. Observational analysis shows that the impacts of the intraseasonal IPCO on TCs over the Indo-western North Pacific features in evident "locational phase lock of TC genesis" and distinct differences in TC frequency. In term of the WNP, when the intraseasonal IPCO is positive phase, there tends to be much more TCs, especially in the South China Sea (SCS), and more TCs generate in the west of the WNP and lower latitude (around 5°-20°N); vice versa. At the positive intraseasonal IPCO phase, the atmosphere gains heat through both sea-air interaction and the latent heat release of cumulus convective condensation, and the anomalous cyclonic circulation weakens the western Pacific subtropical high (WPSH), these conditions do favor the TC genesis. Moreover, the shrinking WPSH, the enhanced heat transfer from sea to air at the lower latitude as well as the westward shifts of heating center and anomalous cyclonic circulation lock TC genesis locations in the west of the WNP and lower latitude. The opposite situation occurs at negative phase. As for the North Indian Ocean (NIO), the TC genesis locations at the positive intraseasonal IPCO phase mainly situate in 13°-20°N and distribute closer to Indian Peninsula, particularly in the Arabian Sea (ARB), in contrast, the spatial distribution is more dispersed at the negative intraseasonal IPCO phase. However, the total TC frequencies at two intraseasonal IPCO phases are similar. These features come largely from the differences in the area featuring conditions between the northern and southern regions of 13°N in the NIO: at the positive intraseasonal IPCO phase, to the northern region of 13°N, the environmental conditions are similar to the case of the WNP except without the

  17. Genetic algorithms used for PWRs refuel management automatic optimization: a new modelling

    International Nuclear Information System (INIS)

    Chapot, Jorge Luiz C.; Schirru, Roberto; Silva, Fernando Carvalho da

    1996-01-01

    A Genetic Algorithms-based system, linking the computer codes GENESIS 5.0 and ANC through the interface ALGER, has been developed aiming the PWRs fuel management optimization. An innovative codification, the Lists Model, has been incorporated to the genetic system, which avoids the use of variants of the standard crossover operator and generates only valid loading patterns in the core. The GENESIS/ALGER/ANC system has been successfully tested in an optimization study for Angra-1 second cycle. (author)

  18. A NeISS collaboration to develop and use e-infrastructure for large-scale social simulation

    OpenAIRE

    Doherty, Thomas; Skipsey, Samuel; Turner, Andy; Watt, John

    2011-01-01

    The National e-Infrastructure for Social Simulation (NeISS) project is focused on\\ud developing e-Infrastructure to support social simulation research. Part of NeISS aims to\\ud provide an interface for running contemporary dynamic demographic social simulation\\ud models as developed in the GENESIS project. These GENESIS models operate at the\\ud individual person level and are stochastic. This paper focuses on support for a simplistic\\ud demographic change model that has a daily time steps, an...

  19. From micromorphology to palaeoenvironment: The MIS 10 to MIS 5 record in Paudorf (Lower Austria)

    DEFF Research Database (Denmark)

    Sprafke, Tobias; Thiel, Christine; Terhorst, Birgit

    2014-01-01

    The loess-palaeosol sequence (LPS) in Paudorf, Lower Austria is characterised by varying dust sedimentation rates, re-deposition with admixture of local rock fragments, erosion and pedogenic overprinting. Detailed semi-quantitative micromorphological analyses reveal the complex genesis of the pal......The loess-palaeosol sequence (LPS) in Paudorf, Lower Austria is characterised by varying dust sedimentation rates, re-deposition with admixture of local rock fragments, erosion and pedogenic overprinting. Detailed semi-quantitative micromorphological analyses reveal the complex genesis...

  20. Study on Geology and Uranium Mineralization at Mentawa Area The Central Kalimantan

    International Nuclear Information System (INIS)

    Bambang-Soetopo

    2004-01-01

    In Mentawa Area, It was found that mineralization of U is associated with tourmaline, quartz, sulfide filling in opened fracture that parallel with schistocity WNW-ESE in direction, mm to cm in thickness, the value of radiometric is in the range of 500-11.000 e/s SPP 2 NF and maximum grade of U is 9.759,25 ppm. Goal of the study mineralogy and geology is to know about character, genesis and para genesis of the U mineralization. The method of this study is microscopic observation and microscopic study from the result of obtained by previous researchers. U mineralization is uraninite associated with molybdenite, pyrite, pyrrhotite, chalcopyrite, rutile, ilmenite and tourmaline. Based on mineral association, it was indicated that U mineralization occurred as pegmatitic pneumatholitic process. Based on those relation and mineral association it was found that Mentawa Area has occurred 4 period para genesis phase. (author)

  1. Musa massif: mapping, petrology and petrochemical, Rio Maria, SE from Para State

    International Nuclear Information System (INIS)

    Gastal, M.C.P.

    1987-01-01

    The petrological, geochemical and geochronological studies allow some insight on the genesis and evolution of the Musa Massif. The different facies of the granitic body are cogenetic, although each of these facies presents some peculiarities in its genesis and evolution. These data suggests that the granite magma evolution was complex or, alternatively, that the facies were generated by liquids derived from different sources. A model of magmatic emplacement, genesis and differentiation is proposed and discussed. The granitic facies show a calc-alkaline compositions, exhibiting strong analogies with cordilleran granites or magnetite granites. An age of 1692 +- 11 Ma (Rb/Sr) with IR of 0,70777 +- 0,00023 was obtained for different facies of Massif. A preliminary attempt to individualize geochronology the principal facies was done and showed that there is a coincidence between the ages and the emplacement sequence of these facies of the pluton. (author)

  2. Is a changing climate affecting the tropical cyclone behavior of Cape Verde?

    Science.gov (United States)

    Emmenegger, T. W.; Mann, M. E.; Evans, J. L.

    2016-12-01

    An existing dataset of synthetic tropical cyclone (TC) tracks derived from climate change simulations were used to explore TC variability within a 250 km radius of the Cape Verde Islands (16.5388N, 23.0418W). The synthetic sets were examined according to genesis point location, track projection, intensity, frequency, and seasonality within the observational era (1851 AD to present). These factors of TC variability have been shown to be strongly related to climate oscillations, thus the historical era was grouped by the increasing and decreasing regimes of sea surface temperature (SST) in the main development region (MDR) of the Atlantic Ocean. Numerous studies have examined Atlantic Basin activity throughout this era; the goal of this study is to investigate possible variations in TC behavior around Cape Verde, ultimately determining whether Cape Verde experiences similar fluctuations in activity as observed basin-wide. We find that several facets of TC variability such as intensity, seasonality, and genesis point location around Cape Verde are not significantly different to that of the entire basin, thus forecasts of the entire basin in these respects may also apply to our site. A long-term trend of increasing TC frequency can be identified basin-wide within the observed set, yet activity around Cape Verde does not display this same behavior observably or in any synthetic set. A relationship between the location of genesis points and the regimes of SST fluctuation is shown to be existent. We find both more observed and synthetic genesis points within the vicinity of Cape Verde during cool periods, and an eastward and equatorward shift in cyclogenesis is evident during warm regimes. This southeastern shift in genesis points attributes to the increased intensities of TCs seen during periods of warmer SST. Years of increased SST are additionally linked to an earlier seasonality in Cape Verde.

  3. The role of liquid-liquid immiscibility and crystal fractionation in the genesis of carbonatite magmas: insights from Kerimasi melt inclusions

    Science.gov (United States)

    Guzmics, Tibor; Zajacz, Zoltán; Mitchell, Roger H.; Szabó, Csaba; Wälle, Markus

    2015-02-01

    melt, whereas Mg, Mn, Fe, Co, Cu, Zn, Al, Sc, Ti, Hf and Zr are partitioned into the silicate melt. Potassium and Rb show no preferential partitioning. Kerimasi melt inclusions show that the immiscible calcic carbonate melt is strongly enriched in Sr, Ba, Pb, LREE, P, W, Mo and S relative to other trace elements. Comparison of our data with experimental results indicates that preferential partitioning of oxidized sulfur (as SO4 2-), Ca and P (as PO4 3-) into the carbonate melt may promote the partitioning of Nb, Ta, Pb and all REE, excluding Sc, into this phase. Therefore, it is suggested that P and S enrichment in calcic carbonate magmas promotes the genesis of REE-rich carbonatites by liquid immiscibility. Our study shows that changes in the partition coefficients of elements between minerals and the coexisting melts along the liquid line of descent are rather significant at Kerimasi. This is why, in addition to the REE, Nb, Ta and Zr are also enriched in Kerimasi calciocarbonatites. We consider significant amounts of apatite and perovskite precipitated from melilite-nephelinite-derived carbonate melt as igneous minerals can have high LREE, Nb and Zr contents relative to other carbonatite minerals.

  4. Origin of ordered and disordered phenomena in plasma

    International Nuclear Information System (INIS)

    Sanduloviciu, M.

    1993-01-01

    Resuming the contents of previously published papers it is shown that ordered and disordered spatial and temporal structures have at their origin a space charge arrangement produced and maintained under conditions in which the excitation and ionization cross-sections increase suddenly in different adjacent regions of a current-carrying gaseous conductor. The appearing double layer structure is the result of a self-organization process which it-self assures the conditions for its existence. Acting as an autonomous body whose genesis implies an energy accumulation mechanism it is possible to explain in a new manner the appearance of ordered and disordered temporal structures in different plasma devices but also the genesis of artificial and natural well-ordered space charge structures such as fireball and ball lightning. Additionally, it is shown that the described double-layer physical scenario can be a tentative model adequate to explain the genesis of prebiotic cellular structures as those appeared under primeval Earth conditions. (Author)

  5. Time-Dependent Simulation of Free-Electron Laser Amplifiers and Oscillators

    CERN Document Server

    Freund, H

    2005-01-01

    Time-dependent FEL simulations use a variety of techniques. Most simulations use a slowly varying envelope approximation (SVEA). One such technique assumes that the envelope varies only in z combined with a field representation as an ensemble of discrete harmonics, which is equivalent to a time-dependent simulation [1] but is computationally prohibitive. A second technique uses an SVEA in both in z and t [2]. The particles and fields are advanced in z using the same process as in steady-state simulations and then the time derivative describing slippage is applied. This is used in wiggler-averaged codes such as GINGER [3] and GENESIS [4]. We describe the inclusion of this technique in the non-wiggler-averaged code MEDUSA [5], which is applied to amplifiers and oscillators. MEDUSA differs from GINGER and GENESIS also in the way the field is treated. GINGER and GENESIS use a field solver and must explicitly propagate the field outside the wiggler oscillators. This is computationally intensive. MEDUSA uses a Gaus...

  6. Mediterranean climate modelling: variability and climate change scenarios

    International Nuclear Information System (INIS)

    Somot, S.

    2005-12-01

    Air-sea fluxes, open-sea deep convection and cyclo-genesis are studied in the Mediterranean with the development of a regional coupled model (AORCM). It accurately simulates these processes and their climate variabilities are quantified and studied. The regional coupling shows a significant impact on the number of winter intense cyclo-genesis as well as on associated air-sea fluxes and precipitation. A lower inter-annual variability than in non-coupled models is simulated for fluxes and deep convection. The feedbacks driving this variability are understood. The climate change response is then analysed for the 21. century with the non-coupled models: cyclo-genesis decreases, associated precipitation increases in spring and autumn and decreases in summer. Moreover, a warming and salting of the Mediterranean as well as a strong weakening of its thermohaline circulation occur. This study also concludes with the necessity of using AORCMs to assess climate change impacts on the Mediterranean. (author)

  7. Cancer Theory from Systems Biology Point of View

    Science.gov (United States)

    Wang, Gaowei; Tang, Ying; Yuan, Ruoshi; Ao, Ping

    In our previous work, we have proposed a novel cancer theory, endogenous network theory, to understand mechanism underlying cancer genesis and development. Recently, we apply this theory to hepatocellular carcinoma (HCC). A core endogenous network of hepatocyte was established by integrating the current understanding of hepatocyte at molecular level. Quantitative description of the endogenous network consisted of a set of stochastic differential equations which could generate many local attractors with obvious or non-obvious biological functions. By comparing with clinical observation and experimental data, the results showed that two robust attractors from the model reproduced the main known features of normal hepatocyte and cancerous hepatocyte respectively at both modular and molecular level. In light of our theory, the genesis and progression of cancer is viewed as transition from normal attractor to HCC attractor. A set of new insights on understanding cancer genesis and progression, and on strategies for cancer prevention, cure, and care were provided.

  8. Intermediate Progenitor Cohorts Differentially Generate Cortical Layers and Require Tbr2 for Timely Acquisition of Neuronal Subtype Identity

    Directory of Open Access Journals (Sweden)

    Anca B. Mihalas

    2016-06-01

    Full Text Available Intermediate progenitors (IPs amplify the production of pyramidal neurons, but their role in selective genesis of cortical layers or neuronal subtypes remains unclear. Using genetic lineage tracing in mice, we find that IPs destined to produce upper cortical layers first appear early in corticogenesis, by embryonic day 11.5. During later corticogenesis, IP laminar fates are progressively limited to upper layers. We examined the role of Tbr2, an IP-specific transcription factor, in laminar fate regulation using Tbr2 conditional mutant mice. Upon Tbr2 inactivation, fewer neurons were produced by immediate differentiation and laminar fates were shifted upward. Genesis of subventricular mitoses was, however, not reduced in the context of a Tbr2-null cortex. Instead, neuronal and laminar differentiation were disrupted and delayed. Our findings indicate that upper-layer genesis depends on IPs from many stages of corticogenesis and that Tbr2 regulates the tempo of laminar fate implementation for all cortical layers.

  9. Ground Water Evolution in Halaib and Shalatein Area, South-East Egypt as Indicated by Hydrochemistry and Environmental Isotopes

    International Nuclear Information System (INIS)

    Zagloul, A.; Elewa, H.H.; Abd El-Samie, S.G.

    2000-01-01

    Hydrochemical and the isotope hydrological studies were carried out on four main aquifers in Halaib and Shalatein areas (Basement, Nubian- Sabdstone, Miocene and Quaternar aquifers) from which water samples were examined for detecting the origin, water type and the rechargeable to these aquifers. The genesis of the groundwater in the Basement aquifer in the north-west direction are NaHCO 3 and Na 2 SO 4 which changed to MgCl 2 near the coast. Its isotopic data indicate that rain water is the possible recharge source to this aquifer. The water genesis of the Nubian Sandstone aquifer is NgCI 2 in the flowing springs and Na 2 SO 4 in the deep wells. The range of isotopic depletion values with low salt content show a mixing of palaeo-rain water. In the Miocene and the Quaternary aquifers, CaCI 2 is the groundwater genesis with high dissolved solids and enriched isotopic content suggest that sea water is intrusion and dissolution of lagoons salts

  10. Mediterranean climate modelling: variability and climate change scenarios; Modelisation climatique du Bassin mediterraneen: variabilite et scenarios de changement climatique

    Energy Technology Data Exchange (ETDEWEB)

    Somot, S

    2005-12-15

    Air-sea fluxes, open-sea deep convection and cyclo-genesis are studied in the Mediterranean with the development of a regional coupled model (AORCM). It accurately simulates these processes and their climate variabilities are quantified and studied. The regional coupling shows a significant impact on the number of winter intense cyclo-genesis as well as on associated air-sea fluxes and precipitation. A lower inter-annual variability than in non-coupled models is simulated for fluxes and deep convection. The feedbacks driving this variability are understood. The climate change response is then analysed for the 21. century with the non-coupled models: cyclo-genesis decreases, associated precipitation increases in spring and autumn and decreases in summer. Moreover, a warming and salting of the Mediterranean as well as a strong weakening of its thermohaline circulation occur. This study also concludes with the necessity of using AORCMs to assess climate change impacts on the Mediterranean. (author)

  11. Using the chemical analysis of magnetite to constrain various stages in the formation and genesis of the Kiruna-type chadormalu magnetite-apatite deposit, Bafq district, Central Iran

    Science.gov (United States)

    Heidarian, Hassan; Lentz, David; Alirezaei, Saeed; Peighambari, Sima; Hall, Douglas

    2016-12-01

    Textural and compositional data are presented for different types of magnetite in the Chadormalu iron deposit to discern the genesis of various styles of mineralization. Samples were chosen according to their paragenetic relations to apatite and their host setting: magnetite-apatite veins in the altered host rocks, disseminated magnetite-apatite assemblages in the marginal parts of the main ore body, and massive magnetite associated with irregular apatite veinlets from internal part of the main ore body. Scanning electron microscopy - back scatter electron (SEM-BSE) images reveal that there are three main generations of magnetite in each of the different magnetite-apatite assemblages. Primary magnetite (Mag1) features abundant porosity and a dark appearance. A second generation of magnetite (Mag2) replacing Mag1 shows a lighter appearance with both sharp and gradational contacts with the primary magnetite crystals. The two magnetite types are related to dissolution-precipitation processes due to changing physico-chemical parameters of the ore fluids. A third type of magnetite (Mag3) with a recrystallized appearance and foam-like triple junctions was mostly observed in magnetite-apatite veins in the main ore body and in veins hosted by altered rocks. Electron probe microanalyses (EPMA) were utilized to discriminate the various magnetite generations in the different magnetite-apatite assemblages. Applying published elemental discrimination diagrams shows that most primary magnetites fall into the hydrothermal- and Kiruna-type fields. Primary magnetite contains lower FeO (88.77-93.65 wt.%; average 91.5 wt.%), and higher SiO2 (0.21-2.26 wt.%; ave. 0.32 wt.%), Al2O3 (0.001-0.45 wt.%; ave. 0.053 wt.%), and CaO (0.002-0.48 wt.%; ave. 0.078 wt.%) contents, which might be related to magmatically derived fluids. Secondary magnetites have higher FeO (89.23-93.49 wt.%; ave. 92.11 wt.%), lower SiO2 (0.037-0.189 wt.%; ave. 0.072 wt.%), Al2O3 (0.004-0.072 wt.%; ave. 0.019 wt

  12. The confirmation of a work hypothesis: a new caldera in the center of the Mexican Volcanic Belt; La confirmacion de una hipotesis de trabajo: una nueva caldera en el centro del Cinturon Volcanico Mexicano

    Energy Technology Data Exchange (ETDEWEB)

    Anguita Virella, Francisco; Pal Verma, Surendra; Milan, Marcos; Garcia Cacho, Luis; Samaniego M, Daniel [Instituto de Investigaciones Electricas, Cuernavaca (Mexico)

    1991-12-31

    After synthesizing the most relevant aspects of the current volcanology and the genesis process of the collapse calderas, a process is described on the location and confirmation of a new caldera (the Mazahua) in the central part of the Mexican Volcanic Belt (MVB). [Espanol] Tras sintetizar los aspectos mas destacados de la vulcanologia actual y el proceso de genesis de las calderas de colapso, se describe el proceso de localizacion y confirmacion de una nueva caldera (la Mazahua) en la parte central del Cinturon Volcanico Mexicano (CVM).

  13. Begetting machinery II – Evolutionärer Algorithmus und technische Evolution

    Directory of Open Access Journals (Sweden)

    Rothenhäusler, Andie

    2011-10-01

    Full Text Available In the 1970s and 1980s two new approaches to an evolutionary explanation of technology emerged: While a new generation of sociobiologists increasingly started to view animal and human artifacts as an ,extended phenotype’ of humankind historians and sociologists of technology found in an evolutionary genesis of technology a third way between technological determinism and a social construction of technology. This evolution of technology seemed able to explain multi-causal coherences in the genesis of technology applicably by using allegedly simple rules.

  14. Evaluation of the vinyl acetate elimination process in methanogenic sludge with oxygen

    International Nuclear Information System (INIS)

    Duran, U.; Monroy, O.; Rendon, B.; Gomez, J.; Ramirez, F.

    2009-01-01

    The vinyl acetate (AV) is a volatile toxic used in the painting manufacture, causing serious problems of contamination in grounds, air and natural bodies of water. Under methanogenic conditions the complete mineralization of the AV has not been obtained, but evidences exist suggesting that with the addition of low oxygen concentrations to methanogenic sludge the elimination of this compound is possible. In this work was studied the respiratory process of elimination of the AV methano genesis and methano genesis with oxygen (1 mg/L-d). (Author)

  15. The confirmation of a work hypothesis: a new caldera in the center of the Mexican Volcanic Belt; La confirmacion de una hipotesis de trabajo: una nueva caldera en el centro del Cinturon Volcanico Mexicano

    Energy Technology Data Exchange (ETDEWEB)

    Anguita Virella, Francisco; Pal Verma, Surendra; Milan, Marcos; Garcia Cacho, Luis; Samaniego M, Daniel [Instituto de Investigaciones Electricas, Cuernavaca (Mexico)

    1992-12-31

    After synthesizing the most relevant aspects of the current volcanology and the genesis process of the collapse calderas, a process is described on the location and confirmation of a new caldera (the Mazahua) in the central part of the Mexican Volcanic Belt (MVB). [Espanol] Tras sintetizar los aspectos mas destacados de la vulcanologia actual y el proceso de genesis de las calderas de colapso, se describe el proceso de localizacion y confirmacion de una nueva caldera (la Mazahua) en la parte central del Cinturon Volcanico Mexicano (CVM).

  16. Genesis and Development of Soils along Different Geomorphic Surfaces in Kouh Birk Area, Mehrestan City

    Directory of Open Access Journals (Sweden)

    Mohammad Akbar Bahoorzahi

    2017-02-01

    Full Text Available Introduction: The optimum and sustainable use of soil is only possible with correct and complete understanding of its properties. The objectives of the present research were to study 1 genesis and development of soils related to different geomorphic surfaces in Kouh Birk Area (Mehrestan City, 2 Soil classification according to Soil Taxonomy (2014 and WRB (2014 systems, and 3 physicochemical properties, clay mineralogy and micromorphology of soils. Materials and Methods: Mean annual rainfall and soil temperature in the selected location are 153.46 mm and 19.6 oC, respectively. From geological point of view, the studied area is a part of west and south west zones and Flysch zone of east Iran. Soil temperature and moisture regimes of this part are thermic and aridic, respectively. Eight representative pedons on different surfaces including rock pediment, mantled pediment, Alluvial fan and Upper terraces were selected, sampled, and described. Routine physicochemical analyses, clay mineralogy, and micromorphological observations performed on soil samples. Soil reaction, texture, electrical conductivity, calcium carbonate, and gypsum were identified. Four samples including Bt horizon of pedon 1, Bk1 horizon of pedon 4, By2 horizon of pedon 5 and Bk1 horizon of pedon 7 were selected for clay mineralogy investigations. Four slides including Mg saturated, Mg saturated treated with ethylene glycol, K saturated, and K saturated heated up to 550 oC were analyzed. A Brucker X-Ray diffractometer at 40 kV and 30 mA was used for XRD analyses. Undisturbed soil samples from Bt horizon of pedon 1, Bk2 horizon of pedon 2, Btn horizon of pedon 3, By2 horizon of pedon 5, Bk1 horizon of pedon 7, and By1 horizon of pedon 8 were selected for micromorphological observations. A vestapol resin with stearic acid and cobalt as hardener was used for soil impregnation. Bk-Pol petrographic microscope was used for micromorphology investigations. Results and Discussion: Due to

  17. Microsporogênese em clones normais e tetraplóides de Hevea brasiliensis Muell.-Arg Microsporo genesis in normal and tetraploid Hevea brasiliensis (Muell.-Arg.

    Directory of Open Access Journals (Sweden)

    Cândida H. T. M. Conagin

    1971-01-01

    Full Text Available Pesquisas sôbre o efeito da colquicina em Hevea brasiliensis Muell.-Arg. realizadas anteriormente levaram à obtenção de clones com número duplicado de cromossomos; tais clones, atualmente em fase de amplas e detalhadas observações (6, floresceram em 1969, pela primeira vez. Foi então realizado um estudo citológico comparativo da microsporo-gènese de duas plantas, uma pertencente ao clone normal n.° 3064, com 2n = 36 cromossomos, e outra pertencente ao clone duplicado n.° 3065, com 2n=72 cromossomos. Ambos são considerados clones gêmeos, porque foram obtidos de uma mesma semente, por técnica especial (7. Na planta com 2n = 36 cromossomos, o processo meiótico é normal, dando tétrades perfeitas e grãos de pólen aparentemente funcionais. A planta 3065, com 2n=72 cromossomos, apresenta, além de células-mães de pólen que se dividem normalmente, outras que no final da meiose produzem tétrades anormais, com micrócitos excedentes e grãos de pólen vazios. Caracteriza-se também por grãos de pólen que não passam pelas divisões mitóticas, isto é, apresentam sempre um núcleo só, que não se divide. Em virtude destas primeiras observações pode-se formular uma hipótese de esterilidade masculina para o clone em estudo.Previous works on Hevea brasiliensis Muell.-Arg. produced several pairs of twin clones, one member having the normal chromosome number and the other the duplicated set after colchicine treatment. Plants of normal clone 3064 are fertile and have 32 chromosomes. Microsporogenesis is normal, producing only normal tetrads of four microsporocytes. The resulting pollen grains have three germinal pores. Grains in different stages of development could be noticed, from one-nucleated cytoplasm to the two-nucleated reproductive cell, which undoubtedly means normal game to genesis. On the other hand plants of the duplicated twin clone 3065, blossomed during the year of 1969 for the first time. Microsporogenesis studied

  18. Probabilistic discrimination between large-scale environments of intensifying and decaying African Easterly Waves

    Energy Technology Data Exchange (ETDEWEB)

    Agudelo, Paula A. [Area Hidrometria e Instrumentacion Carrera, Empresas Publicas de Medellin, Medellin (Colombia); Hoyos, Carlos D.; Curry, Judith A.; Webster, Peter J. [School of Earth and Atmospheric Sciences, Georgia Institute of Technology, Atlanta, GA (United States)

    2011-04-15

    About 50-60% of Atlantic tropical cyclones (TCs) including nearly 85% of intense hurricanes have their origins as African Easterly Waves (AEWs). However, predicting the likelihood of AEW intensification remains a difficult task. We have developed a Bayesian diagnostic methodology to understand genesis of North Atlantic TCs spawned by AEWs through the examination of the characteristics of the AEW itself together with the large-scale environment, resulting in a probabilistic discrimination between large-scale environments associated with intensifying and decaying AEWs. The methodology is based on a new objective and automatic AEW tracking scheme used for the period 1980 to 2001 based on spatio-temporally Fourier-filtered relative vorticity and meridional winds at different levels and outgoing long wave radiation. Using the AEW and Hurricane Best Track Files (HURDAT) data sets, probability density functions of environmental variables that discriminate between AEWs that decay, become TCs or become major hurricanes are determined. Results indicate that the initial amplitude of the AEWs is a major determinant for TC genesis, and that TC genesis risk increases when the wave enters an environment characterized by pre-existing large-scale convergence and moist convection. For the prediction of genesis, the most useful variables are column integrated heating, vertical velocity and specific humidity, and a combined form of divergence and vertical velocity and SST. It is also found that the state of the large-scale environment modulates the annual cycle and interannual variability of the AEW intensification efficiency. (orig.)

  19. Myc contribution to γ-ray induced thymic lymphomas in mice of different genetic predispositions

    International Nuclear Information System (INIS)

    Sato, Toshihiro

    2008-01-01

    Myc gene has been suggested to be one of radiation targets in early genesis of γ ray-induced thymic lymphoma where Myc trisomy often occurs, and Myc activation results in p53 activation and apoptosis. The purpose of this study is to see the effects of radiation and mutation on Myc activation in the mouse. The lymphoma was induced by a single exposure of 3 Gy γ ray in BALB/c Bcl11b/Rit+/- and MSM p53-/- mice at 4 weeks after birth and by 4 weekly exposures of 2.5 Gy in p53+/- mouse. Genetic allele analysis for trisomy identification in the lymphoma was done by quantitative PCR using brain DNA as a control. Myc trisomy was found in the lymphoma of p53+/- mouse in 62% (23/37 animals) and of p53+/+, 66% (23/25), a similar frequency, suggesting that the target of radiation was not only the Myc activation. In addition, Myc trisomy frequency was 15% (4/27) in the lymphoma of Bcl11b+/+p53+/- and 36% (9/25), in heterozygote Bcl11b+/-. This finding suggested that the functional failure of Bcl11b reduced the contribution of Myc trisomy to the genesis. It was concluded that contribution of Myc trisomy to genesis of the lymphoma was dependent on genetic predisposition, and Myc-activated-, Bcl11b/Rit1-signal pathways played a parallel role in the genesis. (R.T.)

  20. The genesis of adiabatic shear bands

    Czech Academy of Sciences Publication Activity Database

    Landau, P.; Osovski, S.; Venkert, A.; Gärtnerová, Viera; Rittel, D.

    2016-01-01

    Roč. 6, Nov (2016), s. 1-6, č. článku 37226. ISSN 2045-2322 R&D Projects: GA ČR GBP108/12/G043 Institutional support: RVO:68378271 Keywords : mechanical engineering * mechanical properties * metals and alloys * phase transitions and critical phenomena Subject RIV: BM - Solid Matter Physics ; Magnetism OBOR OECD: Condensed matter physics (including formerly solid state physics, supercond.) Impact factor: 4.259, year: 2016

  1. Angiography in tumors of cartilaginous genesis

    International Nuclear Information System (INIS)

    Korolev, V.I.

    1986-01-01

    Angiography was used for 122 patients with tumors and tumor-like processes of the cartilage. Angiography was carried out by the S. Seldinger method. Normal angioarchitecture was observed in 16 patients with benign tumors (20 patients), characters of malignant tumor are determined in 4 patients. Normal angioarchitecture is determined in 9.4% of patients with chondrosarcoma (102 patients). The examination carried out showed that angiographic symptotics in chondrosarcomas varied depending on the stage, localization and the degree of morphologic differentiation

  2. Genesis and maintenance of "Mediterranean hurricanes"

    Directory of Open Access Journals (Sweden)

    K. Emanuel

    2005-01-01

    Full Text Available Cyclonic storms that closely resemble tropical cyclones in satellite images occasionally form over the Mediterranean Sea. Synoptic and mesoscale analyses of such storms show small, warm-core structure and surface winds sometimes exceeding 25ms-1 over small areas. These analyses, together with numerical simulations, reveal that in their mature stages, such storms intensify and are maintained by a feedback between surface enthalpy fluxes and wind, and as such are isomorphic with tropical cyclones. In this paper, I demonstrate that a cold, upper low over the Mediterranean can produce strong cyclogenesis in an axisymmetric model, thereby showing that baroclinic instability is not necessary during the mature stages of Mediterranean hurricanes.

  3. Genesis of the Lunar Landing Vehicle

    Science.gov (United States)

    Gelzer, Christian

    2009-01-01

    The author examines early research regarding return flight from a Moon landing made prior to President Kennedy's 1961 challenge to put men on the Moon before the end of the decade. Organizations involved in early research include NACA, the Flight Research Center (now Dryden) Bell Aircraft Corporation. The discussion focuses on development of a flight simulator to model the Moon's reduced gravity and development of the Lunar Landing Research Vehicle.

  4. Genesis of tornadoes associated with hurricanes

    Science.gov (United States)

    Gentry, R. C.

    1983-01-01

    The climatological history of hurricane-tornadoes is brought up to date through 1982. Most of the tornadoes either form near the center of the hurricane, from the outer edge of the eyewall outward, or in an area between north and east-southeast of the hurricane center. The blackbody temperatures of the cloud tops which were analyzed for several hurricane-tornadoes that formed in the years 1974, 1975, and 1979, did not furnish strong precursor signals of tornado formation, but followed one of two patterns: either the temperatures were very low, or the tornado formed in areas of strong temperature gradients. Tornadoes with tropical cyclones most frequently occur at 1200-1800 LST, and although most are relatively weak, they can reach the F3 intensity level. Most form in association with the outer rainbands of the hurricane.

  5. Genesis of uranium-gold pyritic conglomerates

    International Nuclear Information System (INIS)

    Myers, W.B.

    1981-01-01

    The ancient pyritic ore conglomerates have a common origin best exemplified by the Witwatersrand deposits. All contain detrital pyrite and uraninite, which are unstable in modern oxygenated environments and were deposited in a reducing atmosphere. The Rand reefs are not similar to modern gold placers. Placers result from the near incapacity of streams and currents to transport coarse gold. Placers as rich as Rand reef occur only in narrow paystreaks within 15 kilometers of a coarse-gold source. The board dispersion of gold in the reefs is due to solution transport of metal complexed as aurous sulfide, leached anoxygenically from crustal rocks, probably from sea-floor basalt, and precipitated by a slow reaction driven by the radioactive decay of detrital uraninite. Radiolysis of water on shallow marine unconformities resulted in diffusion of hydrogen to the atmosphere and a slight excess of hydroxyl free radical in the reef environment. The mild oxidizing tendency slowly dissolved uranium, precipitated gold, and oxygenated thucholite. These actions define a maturing process. A uraninite placer accumulating on an unconformity becomes progressively converted to a gold reef with little residual uraninite. The most mature reefs tend to grade toward the thucholite-seam type, very thin but exceedingly rich in gold. A combination of chemical attack and physical reworking accounts for the general thinness of mature reefs. Pyrite, like uraninite, decreases in abundance with increasing maturity; buffering by pyrite moderated the oxidative depletion of uranium. Where pyrite was scanty or absent, uraninite was completely dissolved by the effects of radiolysis and no ore formed

  6. Ensemble Prediction of Tropical Cyclone Genesis

    Science.gov (United States)

    2017-02-23

    5f. WORK UNIT NUMBER 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) I PRCISOEST, University of Hawaii at Manoa 1680 East - West Road, POST...Tim Li IPRC/SOEST, University of Hawaii at Manoa 1680 East - West Road, POST Building 409B Honolulu, Hawaii 96822 Phone: (808) 956-9427, fax: (808... environment with a near bottom vortex or an environment with a mid- level vortex. Five experiments were designed with different initial vertical vorticity and

  7. Identifying Genes Involved in Paraganglioma Genesis

    NARCIS (Netherlands)

    J. Gaal (José)

    2010-01-01

    textabstractThe paraganglion system is composed of a collection of chromaffin cells that is distributed throughout the body. Embryonically, chromaffin cells arise from the neuroectodermal tissue of the neural crest and are thought to migrate along the innervating nerves or vasculature towards

  8. The genesis of unified gauge theories

    International Nuclear Information System (INIS)

    Kibble, Tom

    1993-01-01

    The theoretical physics group at London's Imperial College in 1959 had three permanent faculty: Abdus Salam, his erstwhile thesis supervisor Paul Matthews, and John C.Taylor. I joined as a lecturer the following year. In those early days we had lots of visitors, both long- and short-term - Murray Gell-Mann, Ken Johnson, John Ward, Lowell Brown, Gordon Feldman and Steven Weinberg. About a year after I arrived we were transferred from the Mathematics to the Physics Department under the formidable Patrick (P.M.S.) Blackett. Having been brought up in the Cavendish Laboratory tradition under Lord Rutherford, Blackett was rather scornful of theoretical physicists, but he knew a good thing when he saw one and had persuaded Salam to join the rapidly expanding Physics Department. In 1960 field theory was widely regarded as very passé. It had had its triumphs: renormalization theory had made sense of divergences, and quantum electrodynamics had been magnificently vindicated. But field theory didn't seem to work for anything else, particularly not for the strong interactions, and was definitely out of fashion. There were, however, a few places in the world where field theory was still studied unashamedly. Imperial College was one. Harvard was certainly another; many of our visitors over the next few years were Julian Schwinger's students

  9. The genesis of surficial uranium deposits

    International Nuclear Information System (INIS)

    Boyle, D.R.

    1984-01-01

    Surficial uranium deposits can form in such diverse environments as calcareous-dolomitic-gypsiferous fluvial and aeolian valley sediments in hot arid and semi-arid regions, oxidizing and reducing alkaline and saline playas, highly organic and/or clay-rich wetland areas, calcareous regoliths in arid terranes, laterites, lake sediments, and highly fractured zones in igneous and metamorphic basement complexes. Formation of ore is governed by the interrelationships between source of ore-forming elements, mechanisms of migration, environment of deposition, climate, preservation, tectonic history and structural framework. The principal factors controlling mobilization of ore-forming elements from source to site of deposition are the availability of elements in source rocks, presence of complexing agents, climate, nature of source rock regolith and structure of source rock terrane. The major processes governing precipitation of uranium in the surficial environment are reduction mechanisms, sorption processes, dissociation of uranyl complexes, change in redox states of ore-forming constituents, evaporation of surface and groundwaters, change in partial pressure of dissolved carbon dioxide, changes in pH, colloidal precipitation, and mixing of two or more surface and groundwaters. One or a number of these processes may be actively involved in ore formation. (author)

  10. Black hole genesis of dark matter

    Science.gov (United States)

    Lennon, Olivier; March-Russell, John; Petrossian-Byrne, Rudin; Tillim, Hannah

    2018-04-01

    We present a purely gravitational infra-red-calculable production mechanism for dark matter (DM) . The source of both the DM relic abundance and the hot Standard Model (SM) plasma is a primordial density of micro black holes (BHs), which evaporate via Hawking emission into both the dark and SM sectors. The mechanism has four qualitatively different regimes depending upon whether the BH evaporation is 'fast' or 'slow' relative to the initial Hubble rate, and whether the mass of the DM particle is 'light' or 'heavy' compared to the initial BH temperature. For each of these regimes we calculate the DM yield, Y, as a function of the initial state and DM mass and spin. In the 'slow' regime Y depends on only the initial BH mass over a wide range of initial conditions, including scenarios where the BHs are a small fraction of the initial energy density. The DM is produced with a highly non-thermal energy spectrum, leading in the 'light' DM mass regime (~260 eV and above depending on DM spin) to a strong constraint from free-streaming, but also possible observational signatures in structure formation in the spin 3/2 and 2 cases. The 'heavy' regime (~1.2 × 108 GeV to MPl depending on spin) is free of these constraints and provides new possibilities for DM detection. In all cases there is a dark radiation component predicted.

  11. Genesis of Preeclampsia: An Epidemiological Approach

    Science.gov (United States)

    Salvador-Moysén, Jaime; Martínez-López, Yolanda; Ramírez-Aranda, José M.; Aguilar-Durán, Marisela; Terrones-González, Alberto

    2012-01-01

    There are analyzed some of the main aspects related to the causality of preeclampsia, privileging two types of models: the clinic model and the epidemiologic model, first one represented by the hypothesis of the reduced placental perfusion and the second one considering the epidemiologic findings related to the high levels of psychosocial stress and its association with preeclampsia. It is reasoned out the relevance of raising the causality of the disease from an interdisciplinary perspective, integrating the valuable information generated from both types, clinical and epidemiologic, and finally a tentative explanatory model of preeclampsia is proposed, the subclinical and sociocultural aspects that predispose and trigger the disease are emphasized making aspects to stand out: the importance of reduced placental perfusion as an indicator of individual risk, and the high levels of physiological stress, as a result of the unfavorable conditions of the psychosocial surroundings (indicator of population risk) of the pregnant women. PMID:22462008

  12. Plasma: the genesis of the word

    OpenAIRE

    Pinheiro, Mario J.

    2007-01-01

    The historical roots of the word plasma are recalled. It is suggested that possibly at the beginning of the researches in low-pressure gas discharges the driving motivation was related to the psychic phenomena investigated by Sir William Crookes.

  13. The Bioeconomy: Genesis and Modern Imperatives

    Directory of Open Access Journals (Sweden)

    Kravchuk Nataliia І.

    2018-02-01

    Full Text Available The history of origin, the essence, properties, and driving forces of the bioeconomy are disclosed. Three approaches to its interpretation are synthesized: technological, resource, and ecological. The foreign experience of implementation of the bioeconomy in economic activity of different branches is generalized. The place of the bioeconomy in development strategy of the leading world countries: USA, Germany, Finland, France, Great Britain, Italy, and participation in this process of the international organizations are researched. It is determined that the bioeconomic system should become a component of the national economy of the country. The socio-economic activity, based on the processes that have a biological basis, promotes: sustainable and efficient solution of problems in the food, chemical, forest industries, mechanical engineering, energy, health protection; formation of food security; preservation of ecological-economic equilibrium. The system of the following determinants of the bioeconomy: stability, entropy, renewal, symbiosis, unorthodoxness, dynamic efficiency has been proposed. The dynamic efficiency is part of a new perspective concept of the circular economics.

  14. The genesis of unified gauge theories

    Energy Technology Data Exchange (ETDEWEB)

    Kibble, Tom

    1993-06-15

    The theoretical physics group at London's Imperial College in 1959 had three permanent faculty: Abdus Salam, his erstwhile thesis supervisor Paul Matthews, and John C.Taylor. I joined as a lecturer the following year. In those early days we had lots of visitors, both long- and short-term - Murray Gell-Mann, Ken Johnson, John Ward, Lowell Brown, Gordon Feldman and Steven Weinberg. About a year after I arrived we were transferred from the Mathematics to the Physics Department under the formidable Patrick (P.M.S.) Blackett. Having been brought up in the Cavendish Laboratory tradition under Lord Rutherford, Blackett was rather scornful of theoretical physicists, but he knew a good thing when he saw one and had persuaded Salam to join the rapidly expanding Physics Department. In 1960 field theory was widely regarded as very passé. It had had its triumphs: renormalization theory had made sense of divergences, and quantum electrodynamics had been magnificently vindicated. But field theory didn't seem to work for anything else, particularly not for the strong interactions, and was definitely out of fashion. There were, however, a few places in the world where field theory was still studied unashamedly. Imperial College was one. Harvard was certainly another; many of our visitors over the next few years were Julian Schwinger's students.

  15. Historical genesis of Hanford Site wastes

    International Nuclear Information System (INIS)

    Gerber, M.S.

    1991-01-01

    This paper acquaints the audience with historical waste practices and policies as they changed over the years at the Hanford Site, and with the generation of the major waste streams of concern in Hanford Site clean-up today. The paper also describes the founding and basic operating history of the Hanford Site, including World War 11 construction and operations, three major postwar expansions (1947-55), the peak years of production (1956-63), production phase downs (1964-the present), and some past suggestions and efforts to chemically treat, open-quotes fractionate,close quotes and/or immobilize Hanford's wastes. Recent events, including the designation of the Hanford Site as the open-quotes flagshipclose quotes of Department of Energy (DOE) waste remediation efforts and the signing of the landmark Hanford Federal Facility Agreement and Consent Order (Tri-Party Agreement), have generated new interest in Hanford's history. Clean-up milestones dictated in this agreement demand information about how, when, in what quantities and mixtures, and under what conditions, Hanford Site wastes were generated and released. This paper presents original, primary-source research into the waste history of the Hanford Site. The earliest, 1940s knowledge base, assumptions and calculations about radioactive and chemical discharges, as discussed in the memos, correspondence and reports of the original Hanford Site (then Hanford Engineer Works) builders and operators, are reviewed. The growth of knowledge, research efforts, and subsequent changes in Site waste disposal policies and practices are traced. Finally, the paper places the current Hanford Site waste remediation endeavors in the broad context of American and world history

  16. The genesis of public health ethics.

    Science.gov (United States)

    Bayer, Ronald; Fairchild, Amy L

    2004-11-01

    As bioethics emerged in the 1960s and 1970s and began to have enormous impacts on the practice of medicine and research--fuelled, by broad socio-political changes that gave rise to the struggles of women, African Americans, gay men and lesbians, and the antiauthoritarianism impulse that characterised the New Left in democratic capitalist societies--little attention was given to the question of the ethics of public health. This was all the more striking since the core values and practices of public health, often entailing the subordination of the individual for the common good, seemed opposed to the ideological impulses of bioethics. Of what relevance is autonomy-focused bioethics for public health, with its mix of justifications including those that are either implicitly or explicitly paternalistic or that seek to impose strictures on individuals and communities in the name of collective welfare? To examine the deep divide between the central commitments of bioethics and the values that animate the practice of public health, we focus on a series of controversies implicating the concepts of privacy, liberty, and paternalism. Recognising the role of moral values in decision-making was a signal contribution of bioethics in its formative period. Over the past three decades a broad array of perspectives emerged under the rubric of bioethics but individualism remains central. As we commence the process of shaping an ethics of public health, it is clear that bioethics is the wrong place to start when thinking about the balances required in defence of the public's health.

  17. The genesis of errors in drawing.

    Science.gov (United States)

    Chamberlain, Rebecca; Wagemans, Johan

    2016-06-01

    The difficulty adults find in drawing objects or scenes from real life is puzzling, assuming that there are few gross individual differences in the phenomenology of visual scenes and in fine motor control in the neurologically healthy population. A review of research concerning the perceptual, motoric and memorial correlates of drawing ability was conducted in order to understand why most adults err when trying to produce faithful representations of objects and scenes. The findings reveal that accurate perception of the subject and of the drawing is at the heart of drawing proficiency, although not to the extent that drawing skill elicits fundamental changes in visual perception. Instead, the decisive role of representational decisions reveals the importance of appropriate segmentation of the visual scene and of the influence of pictorial schemas. This leads to the conclusion that domain-specific, flexible, top-down control of visual attention plays a critical role in development of skill in visual art and may also be a window into creative thinking. Copyright © 2016 Elsevier Ltd. All rights reserved.

  18. The genesis of the golden age

    DEFF Research Database (Denmark)

    Dalgaard, Carl Johan; Strulik, Holger

    2017-01-01

    We develop a life cycle model featuring an optimal retirement decision in the presence of physiological aging. In modeling the aging process we draw on recent advances within the fields of biology and medicine. In the model individuals decide on optimal consumption during life, the age...... of retirement, and (via health investments) the timing of their death. Accordingly, “years in retirement” is fully endogenously determined. Using the model we can account for the evolution of age of retirement and longevity across cohorts born between 1850 and 1940 in the US. Our analysis indicates that 2....../3 of the observed increase in longevity can be accounted for by wage growth, whereas the driver behind the observed rising age of retirement appears to have been technological change in health care. Both technology and income contribute to the rise in years in retirement, but the contribution from income...

  19. Galactic distribution and genesis of pulsars

    International Nuclear Information System (INIS)

    Guseinov, O.H.; Kasumov, F.K.

    1981-01-01

    The radial distribution of pulsars in the Galaxy have been calculated by the authors using the available electron density figure for each pulsar. Also the luminosity function, the evolution of luminosity with age and the birth rate were determined. (Auth.)

  20. Genesis and kinetics of peritoneal macrophages

    International Nuclear Information System (INIS)

    Wacker, H.H.

    1982-01-01

    The author intended to develop an experimental model for investigations of the proliferation kinetics of tissue macrophages, using the example of peritoneal macrophages. To get a suitable cell population, a blood cell population was labelled with 3 H-thymidine and transferred in a parabiotic test. (orig./MG) [de

  1. Radioactive equilibria and disequilibria of U-series nuclides in erupting magmas from Izu arc volcanoes

    International Nuclear Information System (INIS)

    Sato, Jun; Kurihara, Yuichi; Takahashi, Masaomi

    2009-01-01

    Radioactive disequilibria among U-series nuclides are observed in the magmas from volcanoes in the world. Basaltic products from Izu arc volcanoes, including Izu-Oshima and Fuji volcanoes, show 230 Th 238 U and 226 Ra> 230 Th disequilibria, indicating that the addition of U-and Ra-rich fluid from the subducting slab to the mantle wedge at the magma genesis. The disequilibria of 226 Ra> 230 Th in the erupting magmas suggest that the timescale from magma genesis to the eruption may be less than 8000 years. (author)

  2. MaRIE Undulator & XFEL Systems

    Energy Technology Data Exchange (ETDEWEB)

    Nguyen, Dinh Cong [Los Alamos National Laboratory; Marksteiner, Quinn R. [Los Alamos National Laboratory; Anisimov, Petr Mikhaylovich [Los Alamos National Laboratory; Buechler, Cynthia Eileen [Los Alamos National Laboratory

    2015-03-23

    The 22 slides in this presentation treat the subject under the following headings: MaRIE XFEL Performance Parameters, Input Electron Beam Parameters, Undulator Design, Genesis Simulations, Risks, and Summary It is concluded that time-dependent Genesis simulations show the MaRIE XFEL can deliver the number of photons within the required bandwidth, provided a number of assumptions are met; the highest risks are associated with the electron beam driving the XFEL undulator; and risks associated with the undulator and/or distributed seeding technique may be evaluated or retired by performing early validation experiments.

  3. Autoritet, flerstemmighed og forhandling i Genesisapokryfen

    DEFF Research Database (Denmark)

    Hasselbalch, Trine Bjørnung

    2012-01-01

    This investigation attempts to catch a glimpse of the social process of writing the Genesis Apocryphon, and to ponder which kind of authoritativeness was attributed to the textual traditions behind it – biblical and pseudepigraphical alike. The document is seen metaphorically as a palimpsest......, and the different sources and perspectives are interpreted as principally equal in weight and importance. The output is a reading eliciting multiple voices and perspectives within the text, and suggesting that the production and use of the Genesis Apocryphon did not take place simply to carry on authoritative...

  4. Treatment of critical illness polyneuropathy and/or myopathy - a systematic review

    DEFF Research Database (Denmark)

    Ydemann, Mogens; Eddelien, Heidi Shil; Lauritsen, Anne Øberg

    2012-01-01

    The objective was to search the literature with a view to providing a general description of critical illness myopathy/polyneuropathy (CIM/CIP), including its genesis and prevention. Furthermore, it was our aim to determine whether new treatments have occurred in the past five years.......The objective was to search the literature with a view to providing a general description of critical illness myopathy/polyneuropathy (CIM/CIP), including its genesis and prevention. Furthermore, it was our aim to determine whether new treatments have occurred in the past five years....

  5. Aspekte van die genetiese proses by Opperman soos afgelei uit ’n variantestudie van 'Gedagtes by ’n sarkofaag'

    Directory of Open Access Journals (Sweden)

    E. Meihuizen

    2003-08-01

    Full Text Available Aspects of the genetic process in the poetry of D.J. Opperman based on an analysis of different versions of the poem 'Gedagtes by ’n sarkofaag' (Thoughts on a sarcophagus A study of the genesis of a literary text reveals the systematic changes effected by the author during the creative process, and an understanding of these creative tendencies foregrounds structural principles of the final text. In studying a larger corpus of the author’s work, scrutiny of text development affords the means to gain insight into stylistic, semantic and thematic characteristics of the author’s oeuvre. This article focuses on the genesis of D.J. Opperman’s poem “Gedagtes by ’n sarkofaag” within the theoretical framework of Dutch edition theory as represented by Dorleijn (1984, Mathijsen (1997 and De Bruijn (2000 in particular. The different phases of development in the genesis of “Gedagtes by ’n sarkofaag” are identified and represented in a synoptic apparatus. In the analysis of the textual development particular attention is paid to the creation of a symbolic level.

  6. Galilean creation of the inflationary universe

    Energy Technology Data Exchange (ETDEWEB)

    Kobayashi, Tsutomu [Department of Physics, Rikkyo University, Toshima, Tokyo 175-8501 (Japan); Yamaguchi, Masahide [Department of Physics, Tokyo Institute of Technology, Tokyo 152-8551 (Japan); Yokoyama, Jun' ichi, E-mail: tsutomu@rikkyo.ac.jp, E-mail: gucci@phys.titech.ac.jp, E-mail: yokoyama@resceu.s.u-tokyo.ac.jp [Research Center for the Early Universe (RESCEU), Graduate School of Science, The University of Tokyo, Tokyo 113-0033 (Japan)

    2015-07-01

    It has been pointed out that the null energy condition can be violated stably in some non-canonical scalar-field theories. This allows us to consider the Galilean Genesis scenario in which the universe starts expanding from Minkowski spacetime and hence is free from the initial singularity. We use this scenario to study the early-time completion of inflation, pushing forward the recent idea of Pirtskhalava et al. We present a generic form of the Lagrangian governing the background and perturbation dynamics in the Genesis phase, the subsequent inflationary phase, and the graceful exit from inflation, as opposed to employing the effective field theory approach. Our Lagrangian belongs to a more general class of scalar-tensor theories than the Horndeski theory and Gleyzes-Langlois-Piazza-Vernizzi generalization, but still has the same number of the propagating degrees of freedom, and thus can avoid Ostrogradski instabilities. We investigate the generation and evolution of primordial perturbations in this scenario and show that one can indeed construct a stable model of inflation preceded by (generalized) Galilean Genesis.

  7. Galilean creation of the inflationary universe

    Energy Technology Data Exchange (ETDEWEB)

    Kobayashi, Tsutomu [Department of Physics, Rikkyo University,Toshima, Tokyo 175-8501 (Japan); Yamaguchi, Masahide [Department of Physics, Tokyo Institute of Technology,Tokyo 152-8551 (Japan); Yokoyama, Jun’ichi [Research Center for the Early Universe (RESCEU),Graduate School of Science, The University of Tokyo,Tokyo 113-0033 (Japan); Department of Physics, Graduate School of Science, The University of Tokyo,Tokyo 113-0033 (Japan); Kavli Institute for the Physics and Mathematics of the Universe (Kavli IPMU),UTIAS, WPI, The University of Tokyo,Kashiwa, Chiba 277-8568 (Japan)

    2015-07-13

    It has been pointed out that the null energy condition can be violated stably in some non-canonical scalar-field theories. This allows us to consider the Galilean Genesis scenario in which the universe starts expanding from Minkowski spacetime and hence is free from the initial singularity. We use this scenario to study the early-time completion of inflation, pushing forward the recent idea of Pirtskhalava et al. We present a generic form of the Lagrangian governing the background and perturbation dynamics in the Genesis phase, the subsequent inflationary phase, and the graceful exit from inflation, as opposed to employing the effective field theory approach. Our Lagrangian belongs to a more general class of scalar-tensor theories than the Horndeski theory and Gleyzes-Langlois-Piazza-Vernizzi generalization, but still has the same number of the propagating degrees of freedom, and thus can avoid Ostrogradski instabilities. We investigate the generation and evolution of primordial perturbations in this scenario and show that one can indeed construct a stable model of inflation preceded by (generalized) Galilean Genesis.

  8. TRAVERTINE THE RESTORATION STONE FOR THE ZAGREB CATHEDRAL

    Directory of Open Access Journals (Sweden)

    Branko Crnković

    1995-12-01

    Full Text Available Roman travertine San Pietro Classico, from a deposit in the Acque Albule basin near Rome, will be used for the restoration of the cathedral in Zagreb instead of the previosly used lithotamnian limestone. The genesis and properties of travertine are described. Also the differences in genesis and characteristics of travertine and calc-tufa are presented. Travertine and calc-tufa are created by different genetic processes and thus cannot be considered equivalent. Travertine is a dimensional stone that has world-wide significance, while calc-tufa, has only local or at the most some minor regional importance.

  9. Open Source GIS based integrated watershed management

    Science.gov (United States)

    Byrne, J. M.; Lindsay, J.; Berg, A. A.

    2013-12-01

    Optimal land and water management to address future and current resource stresses and allocation challenges requires the development of state-of-the-art geomatics and hydrological modelling tools. Future hydrological modelling tools should be of high resolution, process based with real-time capability to assess changing resource issues critical to short, medium and long-term enviromental management. The objective here is to merge two renowned, well published resource modeling programs to create an source toolbox for integrated land and water management applications. This work will facilitate a much increased efficiency in land and water resource security, management and planning. Following an 'open-source' philosophy, the tools will be computer platform independent with source code freely available, maximizing knowledge transfer and the global value of the proposed research. The envisioned set of water resource management tools will be housed within 'Whitebox Geospatial Analysis Tools'. Whitebox, is an open-source geographical information system (GIS) developed by Dr. John Lindsay at the University of Guelph. The emphasis of the Whitebox project has been to develop a user-friendly interface for advanced spatial analysis in environmental applications. The plugin architecture of the software is ideal for the tight-integration of spatially distributed models and spatial analysis algorithms such as those contained within the GENESYS suite. Open-source development extends knowledge and technology transfer to a broad range of end-users and builds Canadian capability to address complex resource management problems with better tools and expertise for managers in Canada and around the world. GENESYS (Generate Earth Systems Science input) is an innovative, efficient, high-resolution hydro- and agro-meteorological model for complex terrain watersheds developed under the direction of Dr. James Byrne. GENESYS is an outstanding research and applications tool to address

  10. Genesis of diamond inclusions: An integrated cathodoluminescence (CL) and Electron backscatter diffraction (EBSD) study on eclogitic and peridotitic inclusions and their diamond host.

    Science.gov (United States)

    van den Heuvel, Quint; Matveev, Sergei; Drury, Martyn; Gress, Michael; Chinn, Ingrid; Davies, Gareth

    2017-04-01

    inclusions now cut diamond growth zones. In most cases, the growth zonation around inclusions is not well defined due to CL haloes but some inclusions clearly disrupt diamond growth. Crystallographic orientations of diamond and the inclusions, determined using EBSD, revealed that each inclusion has a homogeneous orientation and record no compositional zonation. The diamonds also showed no angular deviations despite many having multiple growth and resorption zones; implying epitaxial growth of diamond. Crystallographic alignment between diamond and inclusions was not recorded for the principle planes and limited to 3 possible coincidences on minor planes from the 24 inclusions studied. The CL data show no evidence of syngenesis for these 3 inclusions. Analyses of two diamonds with inclusion clusters in different growth zones, 400 µm apart, revealed the same chemical composition and orientation, potentially implying they originated from an original larger inclusion. Combined EBSD and CL data suggest that there is no direct orientational correlation (epitaxial growth) between silicate inclusions and the host diamond, even when the mineral phases are of the same symmetry group. The presentation will provide a detailed evaluation of the genesis of individual inclusions.

  11. Comparison of tropical cyclogenesis indices on seasonal to interannual timescales

    Energy Technology Data Exchange (ETDEWEB)

    Menkes, Christophe E. [IRD/UPMC/CNRS/MNHN, IRD, Laboratoire d' Oceanographie et du Climat, Experimentation et Approches Numeriques (LOCEAN), Paris (France); IRD, Noumea Cedex (New Caledonia); Institut de Recherche Pour le Developpement, LOCEAN, IRD/UPMC/MNHN/CNRS, Noumea Cedex (New Caledonia); Lengaigne, Matthieu [IRD/UPMC/CNRS/MNHN, IRD, Laboratoire d' Oceanographie et du Climat, Experimentation et Approches Numeriques (LOCEAN), Paris (France); National Institute of Oceanography, IRD, Goa (India); Marchesiello, Patrick [Laboratoire d' Etudes en Geophysique et Oceanographie Spatiale (LEGOS), IRD, Toulouse (France); Jourdain, Nicolas C. [IRD, Noumea Cedex (New Caledonia); Vincent, Emmanuel M. [IRD/UPMC/CNRS/MNHN, IRD, Laboratoire d' Oceanographie et du Climat, Experimentation et Approches Numeriques (LOCEAN), Paris (France); Lefevre, Jerome [IRD, Noumea Cedex (New Caledonia); Laboratoire d' Etudes en Geophysique et Oceanographie Spatiale (LEGOS), IRD, Toulouse (France); Chauvin, Fabrice; Royer, Jean-Francois [Meteo-France, CNRM/GAME (Meteo-France/CNRS), Toulouse Cedex 01 (France)

    2012-01-15

    This paper evaluates the performances of four cyclogenesis indices against observed tropical cyclone genesis on a global scale over the period 1979-2001. These indices are: the Genesis Potential Index; the Yearly Genesis Parameter; the Modified Yearly Convective Genesis Potential Index; and the Tippett et al. Index (J Clim, 2011), hereafter referred to as TCS. Choosing ERA40, NCEP2, NCEP or JRA25 reanalysis to calculate these indices can yield regional differences but overall does not change the main conclusions arising from this study. By contrast, differences between indices are large and vary depending on the regions and on the timescales considered. All indices except the TCS show an equatorward bias in mean cyclogenesis, especially in the northern hemisphere where this bias can reach 5 . Mean simulated genesis numbers for all indices exhibit large regional discrepancies, which can commonly reach up to {+-}50%. For the seasonal timescales on which the indices are historically fitted, performances also vary widely in terms of amplitude although in general they all reproduce the cyclogenesis seasonality adequately. At the seasonal scale, the TCS seems to be the best fitted index overall. The most striking feature at interannual scales is the inability of all indices to reproduce the observed cyclogenesis amplitude. The indices also lack the ability to reproduce the general interannual phase variability, but they do, however, acceptably reproduce the phase variability linked to El Nino/Southern Oscillation (ENSO) - a major driver of tropical cyclones interannual variations. In terms of cyclogenesis mechanisms that can be inferred from the analysis of the index terms, there are wide variations from one index to another at seasonal and interannual timescales and caution is advised when using these terms from one index only. They do, however, show a very good coherence at ENSO scale thus inspiring confidence in the mechanism interpretations that can be obtained by

  12. The footprints of Saharan air layer and lightning on the formation of tropical depressions over the eastern Atlantic Ocean

    Science.gov (United States)

    Centeno Delgado, Diana C.; Chiao, Sen

    2015-02-01

    The roles of the Saharan Air Layer (SAL) and lightning during genesis of Tropical Depression (TD) 8 (2006) and TD 12 (2010) were investigated in relation to the interaction of the dust outbreaks with each system and their surrounding environment. This study applied data collected from the 2006 NASA African Monsoon Multidisciplinary Analysis and 2010 Genesis and Rapid Intensification Processes projects. Satellite observations from METEOSAT and Moderate Resolution Imaging Spectroradiometer (MODIS)—Aerosol Optical Depth (AOD) were also employed for the study of the dust content. Lightning activity data from the Met Office Arrival Time Difference (ATD) system were used as another parameter to correlate moist convective overturning and a sign of cyclone formation. The AOD and lightning analysis for TD 8 demonstrated the time-lag connection through their positive contribution to TC-genesis. TD 12 developed without strong dust outbreak, but with lower wind shear (2 m s-1) and an organized Mesoscale Convective System (MCS). Overall, the results from the combination of various data analyses in this study support the fact that both systems developed under either strong or weak dust conditions. From these two cases, the location (i.e., the target area) of strong versus weak dust outbreaks, in association with lightning, were essential interactions that impacted TC-genesis. While our dust footprints hypothesis applied under strong dust conditions (i.e., TD 8), other factors (e.g., vertical wind shear, pre-existing vortex and trough location, thermodynamics) need to be evaluated as well. The results from this study suggest that the SAL is not a determining factor that affects the formation of tropical cyclones (i.e., TD 8 and TD 12).

  13. The ability of general circulation models to simulate tropical cyclones and their precursors over the North Atlantic main development region

    Energy Technology Data Exchange (ETDEWEB)

    Daloz, Anne Sophie; Chauvin, Fabrice [Groupe de Modelisation Grande Echelle et Climat, CNRM-GAME, Meteo-France, Toulouse Cedex 1 (France); Walsh, Kevin [University of Melbourne, School of Earth Sciences, Melbourne, VIC (Australia); Lavender, Sally; Abbs, Deborah [CSIRO Atmospheric and Marine Research, Aspendale, VIC (Australia); Roux, Frank [Universite de Toulouse and Centre National de la Recherche Scientifique, Laboratoire d' Aerologie, Toulouse (France)

    2012-10-15

    The ability of General Circulation Models (GCMs) to generate Tropical Cyclones (TCs) over the North Atlantic Main Development Region (MDR; 10-20 N, 20-80 W; Goldenberg and Shapiro in J Clim 9:1169-1187, 1996) is examined through a subset of ocean-atmosphere coupled simulations from the World Climate Research Programme (WCRP) Coupled Model Intercomparison Project phase 3 (CMIP3) multimodel data set and a high-resolution (0.5 ) Sea Surface Temperature (SST)-forced simulation from the Australian Conformal-Cubic Atmospheric Model GCM. The results are compared with National Center for Environmental Prediction (NCEP-2) and European Center for Medium Range Weather Forecasts Re-Analysis (ERA-40) reanalyses over a common period from 1980 to 1998. Important biases in the representation of the TC activity are encountered over the MDR. This study emphasizes the strong link in the GCMs between African Easterly Waves (AEWs) and TC activity in this region. However, the generation of AEWs is not a sufficient condition alone for the models to produce TCs. Precipitation over the Sahel, especially rainfall over the Fouta Djallon highlands (cf. Fig. 1), is playing a role in the generation of TCs over the MDR. The influence of large-scale fields such as SST, vertical wind shear and tropospheric humidity on TC genesis is also examined. The ability of TC genesis indices, such as the Genesis Potential Index and the Convective Yearly Genesis Potential, to represent TC activity over the MDR in simulations at low to high spatial resolutions is analysed. These indices are found to be a reasonable method for comparing cyclogenesis in different models, even though other factors such as AEW activity should also be considered. (orig.)

  14. Salt geologic evaluation of the impact of cryogenic fissures and halokinetic deformation processes on the integrity of the geological barrier of the salt dome Gorleben

    International Nuclear Information System (INIS)

    Hammer, Joerg; Fleig, Stephanie; Mingerzahn, Gerhard

    2012-07-01

    In several salt domes of the area close to Hannover fissures were observed that might be caused by thermally induced fissure formation due to cold periods (cryogenic fissures). Comprehensive substantial-structural analyses are performed as an example for the salt dome Bokeloh with respect to genesis and transferability to the salt dome Gorleben. Based on recent structure-geological, mineralogical-geochemical and micro-paleontological studies and thermo-mechanical modeling a solely thermally induced fissure formation due to cold periods is unlikely for the salt dome Bokeloh. There is a direct relation between the genesis of the salt dome Bokeloh, its regional tectonic site and the fissure formation. Due to the completely different genesis and another regional-tectonic situation the existence of cryogenic fissures is excluded for the salt dome Gorleben. The salt-geologic and experimental studies on the deformation of anhydrite layers in salt domes are summarized and evaluated with respect to the long-term consequences for a potential final repository for high-level heat-generating radioactive waste in the salt dome Gorleben. The studies confirm the older BGR studies that anhydrite layers do not represent hydraulic potential ling-distance liquid paths.

  15. Moisture Sources and Life Cycle of Convective Systems over Western Colombia

    Directory of Open Access Journals (Sweden)

    Meiry Sayuri Sakamoto

    2011-01-01

    Full Text Available This paper describes life cycle and moisture sources of mesoscale convective systems (MCSs observed over western Colombia. Results show that, in general, MCS are more frequent during boreal summer and autumn, and particularly, systems observed in summer season present longer life and larger extension. On the continent, MCS genesis is strongly affected by sea breeze and diurnal heating and presents a peak from 15 to 18 LST. For oceanic systems, the main genesis period is later, from 00 to 03 LST. Continental and oceanic systems present a tendency of westward displacement. Analysis using a Lagrangian approach implemented to estimate air parcel trajectories suggests that, during boreal winter, the main moisture sources are from the Caribbean Sea and tropical north Atlantic, possibly resulting from the moisture-laden trade winds and the land-ocean temperature contrast over northern South America. In summer, it is clear the influence of ITCZ positioning with moisture particles traveling from the tropical Atlantic over Amazonian river basin. In Autumn, Chilean-Peruvian Pacific is the main moisture source, confirming the importance of Chocó low level jet to MCS genesis.

  16. Nuclear engineering as a historical individual and a paradigma

    International Nuclear Information System (INIS)

    Radkau, J.

    1992-01-01

    The author starts his study with considerations on the technology genesis research to decipher the individual 'genes' and their combinations in order to see together with the origin mechanism also the activity mechanisms and thus establish a connection between technology genesis and technology consequences. He then outlines several prospects of nuclear engineering: economical scenarios: push and pull; 'science-based industries', and omnipotence of experience; 'development' - the pseudorevolutionism of technology history; consensus and community of nuclear economy; the power of things, state technology and national technology - styles. The last paragraph deals with the uniqueness of technology history and describes its systematic and practical aspects. Several outlined trends come to an image of technological development under which the entire process is something unique, and innovative models ar to be assigned to certain phases of a singular process. From predetermination of a technology by its genetic stage it follows that 'technology consequence estimation' increasingly moves towards technology genesis, and that for a good reason. Experience, however, does not give cause to particularly great optimism with regard to the shapeability of future technology development by means of a reasonable social discourse. (orig.) [de

  17. A triadic construct in Jubilees 30

    Directory of Open Access Journals (Sweden)

    Pieter M. Venter

    2010-07-01

    Full Text Available Publications on Old Testament ethics often use triadic constructs to explain the moral impact of Biblical passages. In Genesis 11:27–50:26, Ezra 9:6–15, Nehemiah 7:72b–10:40, Damascus Document (CD V:1, 2–6 and Jubilees 8–9 and 23, constructs of three interrelated concepts are used, all related to the issue of marriage. This paper investigates the story of Dinah’s ravishment in the book of Jubilees 30:1–25 and compares it to the original rendition in Genesis 33:18–34:31. The conclusion is drawn that both renditions use a construct of three interrelated concepts. Genesis uses a triad of progeny, marriage and land. The book of Jubilees uses an interrelated construction of Law, identity and marriage. In Jubilees the focus is shifted from the shame of Dinah’s rape to the shame of intermarriage between different groups in Jubilees. Here a cultic-oriented person links the laws revealed to Moses with his particular view on intermarriage and purity/impurity. His purpose is to propagate a new purified identity for the Jews of his day.

  18. O papel dos hormônios leptina e grelina na gênese da obesidade The role of leptin and ghrelin on the genesis of obesity

    Directory of Open Access Journals (Sweden)

    Carla Eduarda Machado Romero

    2006-02-01

    Full Text Available A prevalência da obesidade está aumentando e estudos prospectivos mostram que, em 2025, o Brasil será o quinto país do mundo a apresentar problemas de obesidade em sua população. A etiologia da obesidade não é de fácil identificação, uma vez que a mesma é caracterizada como uma doença multifatorial, ou seja, diversos fatores estão envolvidos em sua gênese, incluindo fatores genéticos, psicológicos, metabólicos e ambientais. Pesquisas recentes na área de metabolismo mostram que o adipócito é capaz de sintetizar várias substâncias e, diferentemente do que se supunha anteriormente, o tecido adiposo não é apenas um sítio de armazenamento de triglicérides, é hoje considerado um órgão endócrino. Dentre as diversas substâncias sintetizadas pelo adipócito, destacam-se a adiponectina, a angiotensina e a leptina. A leptina é um petídeo que desempenha importante papel na regulação da ingestão alimentar e no gasto energético, gerando um aumento na queima de energia e diminuindo a ingestão alimentar. Além dos avanços no estudo da célula adiposa, um novo hormôrnio relacionado ao metabolismo foi descoberto recentemente, a grelina. A grelina é um peptídeo produzido nas células do estômago, e está diretamente envolvida na regulação do balanço energético a curto prazo. Assim, este artigo abordará o papel da leptina e da grelina no controle do peso corporal e as limitações que ainda existem para tratar a obesidade em humanos.The prevalence of obesity is rising around the world and prospective studies show that in 2025, Brazil will be the fifth country in the world to have obesity problems. Multifactorial factors are involved in the genesis of obesity including genetic, psychological, metabolic and environmental factors. Recently, adipocytes have been considered an endocrine tissue capable of producing several substances, including adiponectin, angiotensin and leptin. Leptin is the main peptide produced by

  19. Biomarcadores asociados a riesgo de síndrome metabólico: estudio en personal médico y administrativo de la Facultad de Ciencias de la Salud UNAB - GENESIS II; --Associated biomarkers with metabolic syndrome risk: A study among medical and administrative staff of the UNAB Health Science Faculty - GENESIS II

    Directory of Open Access Journals (Sweden)

    Norma Cecilia Serrano Díaz, MD, MSc

    2011-01-01

    preventive measures to decrease the occurrence or severity of their consequences. Objectives: To establish the prevalence of MS and to determine the behavior of traditional and no traditional cardiovascular risk factors of men and women from Bucaramanga, Colombia. Methodology: GENESIS is a prospective cohort study in 2005 and 2010 assessment. For the second phase, all participants completed a semistructured questionnaire, received clinical evaluation forblood pressure and anthropometric parameters and peripheral blood sampling for measurement of fasting glucose, cholesterol, HDL, triglycerides, CRP, IL-6, Apo AI and Apo B. Results: 66 employees were evaluated for second phase. The prevalence of MS was 18.2%. Among them, the male population had the highest values of waist circumference, glucose, triglycerides, Apo B and Apo B/Apo AI, compared with women. In Follow-up study, 44 people were assessed on two occasions (2005 and 2010; female population showed a significant increase in waist circumference, cholesterol, HDL and blood glucose levels, and decrease in CRP compared with men. Conclusion: Therecognition of traditional and non-conventional risk factors, andthe differences between genders would help to optimize cardiovascular risk stratification and therefore better prevention of CVD in the future.

  20. The effective field theory of nonsingular cosmology: II

    Energy Technology Data Exchange (ETDEWEB)

    Cai, Yong; Li, Hai-Guang [University of Chinese Academy of Sciences, School of Physics, Beijing (China); Qiu, Taotao [Central China Normal University, Institute of Astrophysics, Wuhan (China); Piao, Yun-Song [University of Chinese Academy of Sciences, School of Physics, Beijing (China); Chinese Academy of Sciences, Institute of Theoretical Physics, P.O. Box 2735, Beijing (China)

    2017-06-15

    Based on the effective field theory (EFT) of cosmological perturbations, we explicitly clarify the pathology in nonsingular cubic Galileon models and show how to cure it in EFT with new insights into this issue. With the least set of EFT operators that are capable to avoid instabilities in nonsingular cosmologies, we construct a nonsingular model dubbed the Genesis-inflation model, in which a slowly expanding phase (namely, Genesis) with increasing energy density is followed by slow-roll inflation. The spectrum of the primordial perturbation may be simulated numerically, which shows itself a large-scale cutoff, as the large-scale anomalies in CMB might be a hint for. (orig.)

  1. Liver physiological polyploidization: MicroRNA-122 a key regulator.

    Science.gov (United States)

    Celton-Morizur, Séverine; Desdouets, Chantal

    2017-03-01

    Polyploidy is defined as an increase in genome DNA content and is observed in all mammalian species. Polyploidy is a common characteristic of hepatocytes. Polyploidization occurs mainly during liver development, but also in adults with increasing age or due to cellular stress. During liver development, hepatocytes polyploidization occurs through cytokinesis failure leading to the genesis of binucleate hepatocytes. Recently, Hsu et al. demonstrated that miR-122 is a key regulator of hepatic binucleation. In fact, during liver development, miR-122 directly antagonizes procytokinesis targets and thus induces cytokinesis failure leading to the genesis of binucleate hepatocytes. Copyright © 2016 Elsevier Masson SAS. All rights reserved.

  2. Special relativity and the Michelson-Morley experiment

    International Nuclear Information System (INIS)

    Chapman, B.R.

    1979-01-01

    It is stated that contrary to most textbook statements about the origins of relativity, there is no real evidence to support the existence of a causal relationship between Michelson's 'crucial' experiment on ether drift and Einstein's enunciation of special relativity. Selective but, it is believed by the author, representative evidence elating to the genesis of the theory of special relativity is presented. Since this evidence contradicts both the substance and the spirit of most textbook references to that genesis, it is thought by the author to have some pedagogic significance for those attempting to teach both the process and the content of physics. (U.K.)

  3. T Cell Genesis: In Vitro Veritas Est?

    OpenAIRE

    Brauer, Patrick M.; Singh, Jastaranpreet; Xhiku, Sintia; Zúñiga-Pflücker, Juan Carlos

    2016-01-01

    T cells, as orchestrators of the adaptive immune response, serve important physiological and potentially therapeutic roles, for example in cancer immunotherapy. T cells are readily isolated from patients; however, the yield of antigen-specific T cells is limited, thus making their clinical use challenging. Therefore, the generation of T lymphocytes from hematopoietic stem/progenitor cells (HSPCs) and human pluripotent stem cells (PSCs) in vitro provides an attractive method for large-scale pr...

  4. Genesis and Evolution of Digital Payment Platforms

    DEFF Research Database (Denmark)

    Hjelholt, Morten; Damsgaard, Jan

    2012-01-01

    Payment transactions through the use of physical coins, bank notes or credit cards have for centuries been the standard formats of exchanging money. Recently online and mobile digital payment platforms has entered the stage as contenders to this position and possibly could penetrate societies...... thoroughly and substitute current payment standards in the decades to come. This paper portrays how digital payment paltforms evolve in socio-technical niches and how various technological platforms aim for institutional attention in their attempt to challenge earlier platforms and standards. The paper...... applies a co-evolutionary multilevel perspective to model the interplay and processes between technology and society wherein digital payment platforms potentially will substitute other payment platforms just like the credit card negated the check. On this basis this paper formulate a multilevel conceptual...

  5. Forms and genesis of species abundance distributions

    Directory of Open Access Journals (Sweden)

    Evans O. Ochiaga

    2015-12-01

    Full Text Available Species abundance distribution (SAD is one of the most important metrics in community ecology. SAD curves take a hollow or hyperbolic shape in a histogram plot with many rare species and only a few common species. In general, the shape of SAD is largely log-normally distributed, although the mechanism behind this particular SAD shape still remains elusive. Here, we aim to review four major parametric forms of SAD and three contending mechanisms that could potentially explain this highly skewed form of SAD. The parametric forms reviewed here include log series, negative binomial, lognormal and geometric distributions. The mechanisms reviewed here include the maximum entropy theory of ecology, neutral theory and the theory of proportionate effect.

  6. Genesis of Electroweak Unification and the Higgs

    CERN Multimedia

    CERN. Geneva

    2014-01-01

    I will give a historical account of the developments leading up to the unification of weak and electromagnetic interactions, as I saw them from my standpoint in Imperial College London. I will describe the state of physics in the 1950s, the aim of finding a unified theory of various interactions, the obstacles encountered in trying to unify the weak and electromagnetic interactions, and their eventual resolution, with a brief discussion of the later history culminating in the discovery of the Higgs boson in 2012.

  7. The mammalian ovary from genesis to revelation.

    Science.gov (United States)

    Edson, Mark A; Nagaraja, Ankur K; Matzuk, Martin M

    2009-10-01

    Two major functions of the mammalian ovary are the production of germ cells (oocytes), which allow continuation of the species, and the generation of bioactive molecules, primarily steroids (mainly estrogens and progestins) and peptide growth factors, which are critical for ovarian function, regulation of the hypothalamic-pituitary-ovarian axis, and development of secondary sex characteristics. The female germline is created during embryogenesis when the precursors of primordial germ cells differentiate from somatic lineages of the embryo and take a unique route to reach the urogenital ridge. This undifferentiated gonad will differentiate along a female pathway, and the newly formed oocytes will proliferate and subsequently enter meiosis. At this point, the oocyte has two alternative fates: die, a common destiny of millions of oocytes, or be fertilized, a fate of at most approximately 100 oocytes, depending on the species. At every step from germline development and ovary formation to oogenesis and ovarian development and differentiation, there are coordinated interactions of hundreds of proteins and small RNAs. These studies have helped reproductive biologists to understand not only the normal functioning of the ovary but also the pathophysiology and genetics of diseases such as infertility and ovarian cancer. Over the last two decades, parallel progress has been made in the assisted reproductive technology clinic including better hormonal preparations, prenatal genetic testing, and optimal oocyte and embryo analysis and cryopreservation. Clearly, we have learned much about the mammalian ovary and manipulating its most important cargo, the oocyte, since the birth of Louise Brown over 30 yr ago.

  8. Digital Genesis: Computers, Evolution and Artificial Life

    OpenAIRE

    Taylor, Tim; Dorin, Alan; Korb, Kevin

    2015-01-01

    The application of evolution in the digital realm, with the goal of creating artificial intelligence and artificial life, has a history as long as that of the digital computer itself. We illustrate the intertwined history of these ideas, starting with the early theoretical work of John von Neumann and the pioneering experimental work of Nils Aall Barricelli. We argue that evolutionary thinking and artificial life will continue to play an integral role in the future development of the digital ...

  9. CORRUPTION IN SOUTH AFRICA: GENESIS AND OUTLOOK

    Directory of Open Access Journals (Sweden)

    Natasha Georgieva Hadji Krsteski

    2017-10-01

    Full Text Available Corruption in South Africa includes the private use of public resources, bribery and improper favouritism. South Africa scored 45 points out of 100 on the 2016 Corruption Perceptions Index reported by Transparency International. Corruption Index in South Africa averaged 46.97 Points from 1996 until 2016, reaching an all-time high of 56.80 Points in 1996 and a record low of 41 Points in 2011. A tenderpreneur is common corruption in South Africa. It is an individual who enriches themselves through corrupting the awarding of government tender contracts, mostly based on personal connections and corrupt relationships - although outright bribery might also take place - and sometimes involving an elected or politically appointed official (or his or her family members holding simultaneous business interests. This is often accompanied by overcharging and shoddy workmanship. BEE-fronting is an abuse of the rules governing Black Economic Empowerment (BEE, where qualifying persons are given a seat on the Board of Directors of a company while having no decision-making power in the company, in order to qualify the company for government contracts in terms of BEE.

  10. Anoxic environments and oil source bed genesis

    Energy Technology Data Exchange (ETDEWEB)

    Demaison, G J [Chevron Overseas Petroleum Inc., San Francisco, CA; Moore, G T

    1980-01-01

    The anoxic, aquatic, environment is a mass of water so depleted in oxygen that virtually all aerobic biological activity has ceased. Anoxic conditions occur where the demand for oxygen in the water column exceeds the supply. The specific cause for preferential lipid enrichment probably relates to the biochemistry of anaerobic bacterial activity. Recent evidence suggests that ancient organic-rich sediments containing hydrogen-rich kerogens (potential oil source beds) were deposited in similar anoxic environments. We propose the following classification for modern aquatic anoxic settings: (1) Large anoxic lakes - Permanent stratification promotes development of anoxic bottom water, particularly in large, deep lakes, which are not subject to seasonal overturn, e.g., Lake Tanganyika. (2) Anoxic silled basins - Landlocked silled basins with positive water balance tend to become anoxic. Typical are the Baltic and Black Seas. In arid region seas (Red and Mediterranean Seas), evaporation exceeds river inflow, causing negative water balance and well-aerated, nutrient-depleted bottom waters. (3) Anoxic layers caused by upwelling - Develop only when the oxygen supply in deep water cannot match demand by decaying organisms. Examples are the Benguela current and Peru coastal upwelling. (4) Open ocean anoxic layers - Found at intermediate depths in the northeastern Pacific and northern Indian Oceans; due to distance from deep, oxygenated polar water sources. Analogous to world-wide anoxic events at times of global climatic warm-ups and major transgressions, as in late Jurassic and middle Cretaceous time. Petroleum exploration can be greatly assisted by using geochemistry to identify paleo-anoxic events in the stratigraphic record. Recognition of the proposed anoxic models in ancient sedimentary basins should help in regional mapping of oil shales and oil-source beds. 17 figures.

  11. Bourgeois Revolution: The Genesis of a Concept

    DEFF Research Database (Denmark)

    Nygaard, Bertel

    2006-01-01

    The concept ‘bourgeois revolution' developed through a particular synthesis of three world views, each with its own period of dominance in Western thought. In the enlightenment views of civilization history developing in Scotland and France from the 1740's till about 1800, materialist notions...

  12. Reactive transport and the genesis of kimberlites

    DEFF Research Database (Denmark)

    Pilbeam, Llewellyn; Nielsen, Troels; Waight, Tod Earle

    was short magmatic temperatures of ~900oC were supported. ! [1] Nielsen & Sand (2008), Canadian Mineralogist 46, 1043- 1061 [2] Ardnt, Guitreau, Boullier, Le Roex, Tommasi, Cordier & Sobolev (2010), Journal of Petrology 51, 573-602 [3] Mitchell (2008), Journal of Volcanology and Geothermal Research 174, 1...

  13. Genesis of Business Tourism in the World

    Directory of Open Access Journals (Sweden)

    Тamara E. Rastegaeva

    2012-05-01

    Full Text Available There are many elements of activities of people which fall under category of business travel in each historical era. Forming of the modern market of the international business meetings occurred in the sixties the XX century when international associations claimed congresses, conferences. Today, business travel became an integral part of modern production process.

  14. Genesis of dwarf galaxies in interacting system

    International Nuclear Information System (INIS)

    Duc, Pierre-Alain

    1995-01-01

    This research thesis addresses the study of interacting and merging galaxies, and more particularly the associated stellar formation episodes. The author first reports an analysis of the central regions of these objects by studying a specific class among them, i.e. galaxies discovered by the IRAS satellite which are ultra-luminous in the far infrared. The author presents results obtained by optical and infrared imagery and spectroscopy of a complete sample of objects located in the southern hemisphere. In the second part, the author focusses on outside regions of interacting galaxies, discusses the observation of filaments formed under the influence of tidal forces acting during galactic collisions, and of condensations which are as luminous as dwarf galaxies. Then a multi-wavelength study of several neighbouring systems revealed the existence of a specific class of objects, the tidal dwarf galaxies, which are formed from stellar and gaseous material snatched from the disk of interacting galaxies. Gas-rich tidal dwarf galaxies contain, like dwarf irregular galaxies or blue compact galaxies, newly formed stars. But, in opposition with these ones, they are richer in heavy elements: this is one of the consequences of a specific mode of galactic formation based on a cosmic recycling [fr

  15. The Genesis of August 2017 Nepal Floods

    Science.gov (United States)

    Uprety, M.; Dugar, S.; Gautam, D.; Budimir, M.; Parajuli, B.; Kharbuja, R. G.

    2017-12-01

    The 2017 monsoon in Nepal was normal until mid-August 2017 when a low pressure system that formed parallel to the foothills of the Churia range brought significant amount of rain in the southern Terai belt. Rivers from East to West swelled as many of them crossed the pre-defined warning thresholds, and rainfall depths in excess of 200 mm to 600 mm were recorded in over a dozen meteorological stations across the country between 11th and 13th of August. The West Rapti River recorded water level of approximately 9 meters while the adjacent Babai River crossed 10 meters and smaller rivers such as Riu Khola and Kankai rose up to 4.8 meters and 5.5 meters respectively, well above danger levels for consecutive days. Early warning systems established in the aforementioned rivers were critical to saving lives and livelihoods. However the severity of flash floods from intermittent streams that originate from the Churia range caught people unaware and led to massive water logging and devastation across Eastern and Central Nepal that claimed 96 lives and displaced more than 14.060 families. The Department of Hydrology and Meteorology with help from telecom operators sent more than 6 million SMS messages to communities residing along the floodplains. These messages provided them with critical information on when to evacuate their homes and move to safer grounds, yet the shear spatial scale and extend of floods meant that communities struggled to find refuge on higher ground. Whilst the Global Flood Awareness System (GLoFAS) indicated with medium probability that major rivers across Nepal might swell in mid-August and the 3 day rainfall forecasts from the Numerical Weather Prediction (NWP) consistently indicated heavy precipitation in the southern Terai belt, yet no significant early actions were taken in response to this information. Despite the availability of forecast information on streamflow prediction and rainfall, there was limited pre-emptive actions and now it is imperative that governments, donors and humanitarian responders in Nepal think beyond the traditional disaster response and relief paradigm and move towards developing and investing in a system that links scientific weather forecasts with predefined early preparedness actions which is currently being piloted and can contribute towards minimizing disaster losses.

  16. FEL-Oscillator simulations with Genesis 1.3

    NARCIS (Netherlands)

    Karssenberg, J.G.; van der Slot, Petrus J.M.; Verschuur, Jeroen W.J.; Volokhine, I.; Boller, Klaus J.

    2006-01-01

    Modeling free-electron laser (FEL) oscillators requires calculation of both the light-beam interaction within the undulator and the propagation of the light outside the undulator. We present a paraxial Optical Propagation Code (OPC) based on the Spectral Method and Fresnel Diffraction Integral,

  17. Tablatures : Exposition photographique d'instruments virtuels GENESIS

    OpenAIRE

    Cadoz, Claude

    2012-01-01

    International audience; Le concept de « composer le son », introduit et expérimenté musicalement par Jean-Claude Risset à partir des années 1960 par la synthèse de sons par ordinateur, prolonge, élargit, dépasse et transforme l'acte d'écriture pour des instruments mécano-acoustiques. Il ne résout cependant pas la question de l'instrumentalité, particulièrement mise à mal avec l'ordinateur. Les technologies de modélisation et de simulation numériques pour « écrire l'instrument pour le composer...

  18. Aspects of the Genesis of Linear Perspective

    DEFF Research Database (Denmark)

    Laursen, Bjørn

    This article is a contribution to the study of how sighted and blind people perceive and draw cubes. For many years the author has taught sighted people perspective drawing and published books in Scandinavia about drawing. His point of departure in this article is pointing out typical obstacles s...... of psychology John M. Kennedy, that blind people intuitively and rapidly seem to invent perspective drawing, a phenomenon sighted people in The Middle Ages used more than a hundred years to develop.......This article is a contribution to the study of how sighted and blind people perceive and draw cubes. For many years the author has taught sighted people perspective drawing and published books in Scandinavia about drawing. His point of departure in this article is pointing out typical obstacles...... sighted people run into seeing and drawing linear perspective. Blind people’s conditions for drawing a cube are presented and compared with the ones sighted people meet. The overall aim of this article is to contribute pedagogically and theoretically to explain a basic paradox, pointed out by professor...

  19. In-situ U-Pb, Hf and Re-Os isotopic analyses of the Xiangshan Ni-Cu-Co deposit in Eastern Tianshan (Xinjiang), Central Asia Orogenic Belt: Constraints on the timing and genesis of the mineralization

    Science.gov (United States)

    Han, Chunming; Xiao, Wenjiao; Zhao, Guochun; Ao, Songjian; Zhang, Jien; Qu, Wenjun; Du, Andao

    2010-12-01

    The timing and genesis of the major Ni-Cu-Co sulfide deposit in the Xiangshan intrusion have been studied based on newly obtained in-situ U-Pb, Hf and Re-Os isotopic analyses. The SIMS U-Pb zircon ages of the gabbro hosting the Ni-Cu-Co sulfide deposit indicate that the Xiangshan intrusion was emplaced at 279.6 ± 1.1 Ma (95% confidence level, MSWD = 1.30, n = 15). On the basis of combined geological and geochronological evidence, we suggest that the Xiangshan and other adjacent Ni-Cu deposits were formed in the same period. Sulphides have low common Os concentrations and high Re/Os ratios, similar to sulphide ores from the Duluth, Sally Malay and Voisey Bay complexes. The Re-Os isotopic data from the disseminated and massive ores from the Xiangshan intrusion do not form a single isochron, as they have different initial Os ratios. The Hf and Os isotopic data suggest that the Xiangshan intrusion and associated Ni-Cu-Co mineralization were derived from crustally contaminated mantle melts. The geochemical data show a tholeiitic affinity and a strong suprasubduction zone signature with negative Nb, Sr, and Ti anomalies similar to N-MORB and E-MORB. We suggest that the mafic-ultramafic rocks and associated Ni-Cu mineralization of the Eastern Tianshan orogen formed in an Alaska-type subduction zone-arc setting. Some diagnostic features of ridge-trench interaction are present in the Chinese East Tianshan orogen (e.g. granites, adakites, high-Mg andesites, near-trench magmatism, Alaskan-type mafic-ultramafic complexes, high-temperature metamorphic belts that prograde rapidly from low-grade belts, and orogenic gold deposits). The above distinctive rock groups are probably related to the same thermal event, ridge subduction, as in the Cenozoic orogen of Alaska. We suggest that ridge subduction is the most plausible mechanism to provide the necessary heat. Ridge subduction provides an important promising model for understanding many aspects of the evolution of the Chinese

  20. New idea on the classification of world super-large deposits

    International Nuclear Information System (INIS)

    Tong Hangshou

    2012-01-01

    According to the theory of 'multi factors and compound genesis', 'complexity of mineralization' and 'metallogenic series', this paper proposed a new classification idea on the world super-large deposits with the combination of new results on the study of global background for super-large deposits and the model of 'conjugation of multi-source and focus of multi-factors'. 15 super-large deposits with the reserve over 50000 t were studied as the ases, 6 types and 13 sub-types of economics-genesis have been divided for the super-large deposit. The classification is discoursed with symbols and worlds and brief introduction on typical deposit. (authors)

  1. Relexification in a Northern Norwegian dialect?

    Directory of Open Access Journals (Sweden)

    Hilde Sollid

    2004-01-01

    Full Text Available This paper explores how the process of relexification can contribute to the understanding of the genesis of the new Norwegian dialect of Sappen in Nordreisa. The dialect has emerged in the context of language shift from Finnish to Norwegian, and the dialect syntax has features that might be regarded as products of relexification. One example is declarative main clauses with the finite verb in the third position (V3. The discussion adheres to a more general discussion of approaches to language genesis, where substratist and universalist (and also superstratist theories often are regarded as contrary to each other. I argue that different theories can contribute to the understanding of different aspects of the same question.

  2. A new approach to the use of genetic algorithms to solve the pressurized water reactor's fuel management optimization problem

    Energy Technology Data Exchange (ETDEWEB)

    Chapot, Jorge Luiz C. [ELETRONUCLEAR, Rio de Janeiro, RJ (Brazil); Carvalho Da Silva, Fernando; Schirru, Roberto [COPPE/UFRJ-Nuclear, Rio de Janeiro, RJ (Brazil)

    1999-05-01

    A Genetic Algorithm (GA) based system, coupling the computer codes GENESIS 5.0 and ANC through the interface ALGER has been developed aiming at pressurized water reactor's (PWR) fuel management optimization. An innovative codification, the List Model (LM), has been incorporated into the system. LM avoids the use of heuristic crossover operators and only generates valid nonrepetitive loading patterns in the reactor core. The LM has been used to solve the Traveling Salesman Problem (TSP). The results got for a benchmark problem were very satisfactory, in terms of precision and computational costs. The GENESIS/ALGER/ANC system has been successfully tested in optimization studies for Angra 1 power plant reloads.

  3. Sex specific response in cholesterol level in zebrafish (Danio rerio) after long-term exposure of difenoconazole

    International Nuclear Information System (INIS)

    Mu, Xiyan; Wang, Kai; Chai, Tingting; Zhu, Lizhen; Yang, Yang; Zhang, Jie; Pang, Sen; Wang, Chengju; Li, Xuefeng

    2015-01-01

    Difenoconazole is a widely used triazole fungicide, its extensive application may potentially cause toxic effects on non-target organisms. To investigate the effect of difenoconazole on cholesterol content and related mechanism, adult zebrafish were exposed to environmental related dosage (0.1, 10 and 500 μg/L) difenoconazole. The body weight and hepatic total cholesterol (TCHO) level was tested at 7, 15 and 30 days post exposure (dpe). The expressions of eight cholesterol synthesis genes and one cholesterol metabolism gene were assessed via Quantitative PCR method. The significant decrease of TCHO level in male zebrafish liver was observed at 15 and 30 dpe, which was accompanied by apparent hepatic cholesterol-genesis genes expression decline. In comparison with males, female zebrafish showed different transcription modification of tested genes, and the cholesterol content maintain normal level during the whole exposure. - Highlights: • Difenoconazle could reduce TCHO level in male zebrafish liver. • Difenoconazole could inhibit sterol-genesis genes expression in male zebrafish. • Female zebrafish didn't show obvious change of TCHO level after exposure. • Difenoconazole could inhibit body weight of both male and female zebrafish. - Difenoconazle could reduce cholesterol level and sterol-genesis genes expression in male zebrafish. While female zebrafish showed no obvious cholesterol content change during exposure

  4. Origins and Distribution of Life in the Universe

    CERN Document Server

    CERN. Geneva. Audiovisual Unit; Reille, Daniel

    2002-01-01

    Terrestrial life, defined as a chemical system capable of self-reproduction and also capable of evolution, probably originated from the evolution of reduced organic molecules in liquid water. We are looking for fossilised remnants in old sediments and also for a second genesis of life, artificial in a test tube or natural on another celestial body. On Earth, organic molecules might have been formed in the atmosphere, near hydrothermal vents or delivered by extraterrestrial dust grains. Life might have evolved on early Mars when water existed on the surface. Europa has probably a water subsurface ocean and perhaps hydrothermal systems harbouring a basic life form. The discovery of exoplanets opens the search for a second genesis of life to the whole Universe.

  5. Comment la Terre a-t-elle pu vieillir de plus de quatre milliards d'années en quatre siècles ?

    Science.gov (United States)

    Krivine, Hubert

    2017-05-01

    The history of the determination of the Earth's age is interesting in two ways. First, it is a great school for understanding the genesis of a scientific theory. It stands at the crossroads of almost all scientific disciplines, and also philosophy or even theology. This history shows how what one may well call a ;scientific truth; was established through polemics. Second, that age of 4.567 billion years is not just another figure in the series of ages that would be of concern only to astrophysicists; this scale is the only one that makes it possible to understand the genesis of the marvelous order of the solar system (that Newton attributed to God) and the fantastic complexity of Life on Earth.

  6. Medical practice branding using cable television.

    Science.gov (United States)

    Miaoulis, George; Kissinger, Mark; Sirko-Fiorilli, Mary Ann

    2005-01-01

    Genesis Medical Associates is an independent primary care practice in the suburbs of Pittsburgh. Given competitive pressures, a member of the physician leadership began thinking about the need for the practice to develop an "identity and awareness" program to set the practice apart from the competition. The idea for branding the campaign began when Dr. Rob Potter, Jr., was attending a Pittsburgh Pirates baseball game and a fan said to him, "You're that doctor I see on television" in the nursing home commercial. Triggered by this experience, Potter saw the opportunity to develop an awareness and identity campaign for Genesis. In this article we share the reasons for, the steps taken, and initial results in developing a medical practice branding strategy.

  7. Relevance of the futron/zogby survey conclusions to the current space tourism industry

    Science.gov (United States)

    Ziliotto, Véronique

    2010-06-01

    Thanks to recent technological achievements such as Burt Rutan's SpaceShipOne in 2004, Bigelow's Genesis I in July 2006 and Genesis II in July 2007 and the success of space adventures' flights to the ISS, space tourism is leaving the realm of science-fiction. It is now becoming increasingly familiar to the general public and even recognized by institutional bodies. The Futron/Zogby survey, revised in 2006 and completed with the 2006. Adventurers survey constitutes a good basis to understanding the characteristics of the nascent suborbital market and the profile of the potential customers for both suborbital and orbital travel. The previsions of these studies will be contrasted with recent market and customers' data that was not available at the time.

  8. Eclogite facies rocks

    National Research Council Canada - National Science Library

    Carswell, D. A

    1990-01-01

    ... of eclogite evolution and genesis. The authors present a thorough treatment of the stability relations and geochemistry of these rocks, their intimate association with continental plate collision zones and suture zones...

  9. Biohäkkimine : mikrobioloogia kui kunstimeedium, ehk, Küberkoodist biokoodini / Tiia Johannson

    Index Scriptorium Estoniae

    Johannson, Tiia, 1965-2002

    2001-01-01

    Uus kunstnike kommuun üritab loodust üle kavaldada, kasutades molekulaarbioloogiat uut tüüpi interaktiivse kunsti loomiseks: Eduardo Kac'i jäneseprojekt "GFP Bunny" ja transgeneetiline netiinstallatsioon "Genesis"

  10. A escola de Belas Artes de Pelotas: aspectos de sua gênese e constituição - The escola de Belas Artes de Pelotas: aspects of its genesis and constitution

    Directory of Open Access Journals (Sweden)

    Clarice Rego Magalhães, Giana Lange do Amaral

    2011-03-01

    Full Text Available Resumo Este trabalho aborda a gênese e constituição de uma instituição de ensino de arte: a Escola de Belas Artes de Pelotas (EBA. O objetivo do estudo é esclarecer quais foram as condições que possibilitaram a criação da EBA em março de 1949. A constituição desta narrativa histórica tem por base fontes escritas, formadas pelos  arquivos  da própria instituição, pelo arquivo particular da família da fundadora da Escola, por periódicos locais e  por  trechos do diário da fundadora, além  de fontes  orais.  Pela análise das fontes,  concluímos que o nascimento da EBA se deu por uma conjunção de  fatores, os quais seriam a vocação cultural da cidade, oriunda da sua história peculiar, e  a  atuação  de   personalidades que,  naquele  momento,   fizeram acontecer o fato histórico. Palavras-chave: Escola de Belas Artes; instituição de  ensino  de arte; história da educação; história das instituições escolares.   THE ESCOLA DE BELAS ARTES DE PELOTAS: ASPECTS  OF ITS GENESIS AND CONSTITUTION Abstract This work examines the genesis and constitution of an art teaching institution: the Escola de Belas Artes de Pelotas (EBA. The purpose of this study is to elucidate the  conditions which made possible the creation of EBA in March, 1949.  This historic account is based on written   sources,  namely  the   institution’s   archives,  the   school founder’s  family private archives, local journals  and  exerts from the founder’s diary, besides oral sources. The analysis of the sources led us to conclude that  the  birth  of EBA  occurred as the  result of a conjunction  of  factors  which are  the  town’s  cultural  inclination, derived from its peculiar history, and the actions of some individuals that, at that moment, made the historic fact happen. Keywords: Fine Arts School; art teaching institution; history of education; teaching institutions history.   LA

  11. Analysis of stability parameters in relation to precipitation associated ...

    Indian Academy of Sciences (India)

    erty and crops; human and animal fatalities, and also aviation hazards. ... Keywords. Atmospheric instability; stability indices; Richardson number; vertical wind shear; energy-helicity index; ... ing the genesis and development of severe weather.

  12. GS IGBO: BETTER LATE THAN THE LATE Longinus Chukwuemeka ...

    African Journals Online (AJOL)

    JONATHAN

    The genesis of the university studies sprang from the insatiable human cravings ... who are academically and professionally mature and attend self determination and .... Ahumibe,C.(2002) Philosophizing in Education: A Beginers Handbook.

  13. 69th Annual Meeting | Annual Meetings | Events | Indian Academy of ...

    Indian Academy of Sciences (India)

    14.00 - 17.00. Symposium - Emerging trends in communication technologies. 14.00 - 14.20 ... Towards understanding the genesis of phosphorite deposits ... DISCUSSION MEETING: HUMAN DIVERSITY AND ANCESTRY IN INDIA. Posted on ...

  14. Evaluation of early tissue reactions after lumbar intertransverse process fusion using CT in a rabbit

    International Nuclear Information System (INIS)

    Shinbo, Jun; Mainil-Varlet, Pierre; Watanabe, Atsuya; Pippig, Suzanne; Koener, Jens; Anderson, Suzanne E.

    2010-01-01

    The objective of the study was to evaluate tissue reactions such as bone genesis, cartilage genesis and graft materials in the early phase of lumbar intertransverse process fusion in a rabbit model using computed tomography (CT) imaging with CT intensity (Hounsfield units) measurement, and to compare these data with histological results. Lumbar intertransverse process fusion was performed on 18 rabbits. Four graft materials were used: autograft bone (n=3); collagen membrane soaked with recombinant human bone morphogenetic protein-2 (rhBMP-2) (n=5); granular calcium phosphate (n=5); and granular calcium phosphate coated with rhBMP-2 (n=5). All rabbits were euthanized 3 weeks post-operatively and lumbar spines were removed for CT imaging and histological examination. Computed tomography imaging demonstrated that each fusion mass component had the appropriate CT intensity range. CT also showed the different distributions and intensities of bone genesis in the fusion masses between the groups. Each component of tissue reactions was identified successfully on CT images using the CT intensity difference. Using CT color mapping, these observations could be easily visualized, and the results correlated well with histological findings. The use of CT intensity is an effective approach for observing and comparing early tissue reactions such as newly synthesized bone, newly synthesized cartilage, and graft materials after lumbar intertransverse process fusion in a rabbit model. (orig.)

  15. Mineralogy, chemistry of magnetite and genesis of Korkora-1 iron deposit, east of Takab, NW Iran

    Directory of Open Access Journals (Sweden)

    Mohammad Maanijou

    2014-10-01

    , respectively. Therefore, it fits in the skarn ore deposit domain in Ni/(Cr + Mn versus Ti + V and Ca + Al + Mn versus Ti + V discrimination diagrams of iron ore deposits (Beaudoin et al., 2007. High Mn in the rock samples of Korkora-1 can be resulted from substitution of Fe+2 by Mn+2 in magnetite structure that can be a sign of hydrothermal skarn. Titanium, Mn, V and Zn show a positive correlation and Al, Cu, Mg, P, Si, Ca, Ni and Cr show a negative correlation with Fe. According to the chemistry of magnetite and plotting them on V2O5 versus TiO2 and V2O5 versus Cr2O3 diagrams, it can be recognized that the samples of Korkora-1 deposit resemble exoskarn magnetite of Goto deposit. The analysis of goethite of Korkora-1 show the amount of 2.5 to 4 wt % SiO2, 76 wt % Fe, and Ni (110 ppm without Ti and Cr in its structure. Mineralographical and geochemical evidence from ore, occurrence of iron in contact with carbonates and skarn mineralogy such as garnet, pyroxene, secondary calcite, epidote and chlorite suggest iron skarn genesis for Korkora-1 deposit. Fluids generated from intrusive bodies like diorite and quartz-diorite with variations in physicochemical conditions, produced skarn in contact with carbonates and volcanic rocks. The heat from intrusive bodies caused recrystallization of carbonates and formed marbles in the footwall of the deposit. Meteoric water has also less important contribution in the ore-forming fluids. Fluid inclusion studies show existing of two types of fluids, a low salinity (10 wt % NaCl equiv. and a medium salinity (25 to 30 wt % NaCl equiv. fluid. Mixing magmatic and meteoric waters makes decreasing in the temperatures and deposition of ore fluids. The Korkora-1 deposit formed in four stages: 1 intruding the intrusive bodies, 2 entering Fe and SiO2 into Qom carbonates and forming calc-silicates, 3 mixing magmatic and meteoric fluids, hydrolysis of calc-silicates, consuming H+, instability of Fe complexes and deposition of iron oxides, 4 retrograde

  16. Cytogenesis in the monkey retina

    International Nuclear Information System (INIS)

    La Vail, M.M.; Rapaport, D.H.; Rakic, P.

    1991-01-01

    Time of cell origin in the retina of the rhesus monkey (Macaca mulatta) was studied by plotting the number of heavily radiolabeled nuclei in autoradiograms prepared from 2- to 6-month-old animals, each of which was exposed to a pulse of 3H-thymidine (3H-TdR) on a single embryonic (E) or postnatal (P) day. Cell birth in the monkey retina begins just after E27, and approximately 96% of cells are generated by E120. The remaining cells are produced during the last (approximately 45) prenatal days and into the first several weeks after birth. Cell genesis begins near the fovea, and proceeds towards the periphery. Cell division largely ceases in the foveal and perifoveal regions by E56. Despite extensive overlap, a class-specific sequence of cell birth was observed. Ganglion and horizontal cells, which are born first, have largely congruent periods of cell genesis with the peak between E38 and E43, and termination around E70. The first labeled cones were apparent by E33, and their highest density was achieved between E43 and E56, tapering to low values at E70, although some cones are generated in the far periphery as late as E110. Amacrine cells are next in the cell birth sequence and begin genesis at E43, reach a peak production between E56 and E85, and cease by E110. Bipolar cell birth begins at the same time as amacrines, but appears to be separate from them temporally since their production reaches a peak between E56 and E102, and persists beyond the day of birth. Mueller cells and rod photoreceptors, which begin to be generated at E45, achieve a peak, and decrease in density at the same time as bipolar cells, but continue genesis at low density on the day of birth. Thus, bipolar, Mueller, and rod cells have a similar time of origin

  17. [Use of antiseptic dekasan in complex treatment of peritonitis].

    Science.gov (United States)

    Nazirov, F N; Aripova, N U; Makhkamova, M N; Dzhamalov, S I; Pulatov, M M; Magzumov, I Kh; Isroilov, B N

    2014-01-01

    Experience in treatment of 91 patients with peritonitis on various genesis using antiseptic Dekasan are presented. A marked clinical efficacy compared with that of other antiseptics in the complex treatment of peritonitis was noted.

  18. Saaremaa / Raul Salumäe

    Index Scriptorium Estoniae

    Salumäe, Raul

    2003-01-01

    Kuressaare linnuse keldrisaalis poola kunstniku Magdalena Schmidt-Gora näitus-installatsioon "Genesis I, II", 3. korruse väikeses saalis läti fotograafi Astra Tomsone fotonäitus "Loojang minu akna taga"

  19. Nonlinear morphoelastic plates I: Genesis of residual stress

    KAUST Repository

    McMahon, J.

    2011-04-28

    Volumetric growth of an elastic body may give rise to residual stress. Here a rigorous analysis is given of the residual strains and stresses generated by growth in the axisymmetric Kirchhoff plate. Balance equations are derived via the Global Constraint Principle, growth is incorporated via a multiplicative decomposition of the deformation gradient, and the system is closed by a response function. The particular case of a compressible neo-Hookean material is analyzed, and the existence of residually stressed states is established. © SAGE Publications 2011.

  20. Glycolytic overload and the genesis of breast cancer.

    Science.gov (United States)

    Robson, J R

    1984-03-01

    It is suggested that the development of breast cancer is due to overloading of the glycolytic pathways. An excess of substrates or an excessive delivery rate of substrates to the Krebs Cycle is believed to result in the formation of acetyl CoA. Feedback mechanisms controlling the conversion of acetyl CoA to cholesterol may be overcome; the resulting high concentration of cholesterol induces the formation of pregnenolone which may then be converted into androgens, estrogens and progesterone. These steroids are in addition to those produced by gonads and adrenal glands. Glycolytic overload is also associated with an increase in fat stores which have been shown to be the site of interconversion of sex hormones. Excess sex hormones or abnormal sex hormones are believed to be the cause of breast cancer. The hypothesis presented links glycolytic overload with clinical biochemical phenomena and explains some of the anomalies observed in breast cancer experience in different ethnic groups. Changes in dietary habits during the history of man resulting in " gorging " and the consumption of highly refined sugars are possible causes of glycolytic overload. So, also, is impaired thermogenesis due to Brown Fat deficits in certain ethnic groups.

  1. Spin-down of radio millisecond pulsars at genesis.

    Science.gov (United States)

    Tauris, Thomas M

    2012-02-03

    Millisecond pulsars are old neutron stars that have been spun up to high rotational frequencies via accretion of mass from a binary companion star. An important issue for understanding the physics of the early spin evolution of millisecond pulsars is the impact of the expanding magnetosphere during the terminal stages of the mass-transfer process. Here, I report binary stellar evolution calculations that show that the braking torque acting on a neutron star, when the companion star decouples from its Roche lobe, is able to dissipate >50% of the rotational energy of the pulsar. This effect may explain the apparent difference in observed spin distributions between x-ray and radio millisecond pulsars and help account for the noticeable age discrepancy with their young white dwarf companions.

  2. NATURAL BASES OF GENESIS OF UNTZUKUL ORNAMENTAL ART

    Directory of Open Access Journals (Sweden)

    G. G. GAZIMAGOMEDOV

    2010-01-01

    Full Text Available The work deals with Untzukul ornamental hatching wood by metal - it is the only phenomena in decoration applied art. Special attention is paid to succession of the traditions important for conservation and further development of the natural art trade of Daghestan republic.

  3. Kosovo’s Crisis: Genesis of a Problem

    Science.gov (United States)

    2013-03-01

    1913 it attacked the Serbian forces. The Second Balkan War also involved Greece and Romania . For a short period, Bulgaria was defeated and it lost...formal declaration of war, attacked Serbia in June 1913, and the Second Balkan War began. Serbia, Montenegro, Romania , Greece and the Ottoman Empire...Serbian army was reorganized, and, after three months, it was sent to the Thessaloniki front. After a breakthrough at the front on September 14, 1918

  4. [Results of genesis and diagnosis of schizoid disorders].

    Science.gov (United States)

    Lieberz, K

    1991-01-01

    A group of 25 schizoid patients were compared with 76 neurotic patients and 103 healthy persons in terms of perceived parent imago and family dynamics. The following findings should be emphasized: 1. Schizoid persons can be distinguished well from other persons on the basis of their experience of family. 2. A clear delimitation of schizoid persons from neurotic persons is possible only when the factor of sex is considered. 3. Schizoid women differ from neurotic women in terms of their distinctive mother experience: The mothers of schizoid women are marked by a weak ego and are apprehensive and extremely permissive. 4. Schizoid men differ from neurotic men both in terms of a distinctive mother experience and a distinctive father experience. In their case, a negative mother imago is contrasted with an ambivalent father imago. Neurotic men, on the other hand, possess a mother imago nearly as positive as that of healthy men, although they do exhibit a distinctly more negative father imago. 5. Schizoid women differ from schizoid men in terms of a distinctively negative mother imago. Whereas the mothers of schizoid women are experienced above all as exhibiting a weak ego and traits of dependency, the mothers of schizoid men are perceived more as being strong and independent.

  5. Genesis and Development of the Concept of Evolution

    Directory of Open Access Journals (Sweden)

    Hilde Sánchez Morales

    2016-02-01

    Full Text Available Darwin's evolutionary theory, on the date of the publication of On the Origin of Species (1859, immediately attracted the attention, but received unanimous acceptance. Many considered it contrary to religious orthodoxy and a threat that threatened the traditional ideological nature. Others agreed with restrictions and other taken it as absolute truth. Admittedly that the educated opinion of the Victorian Era was strongly conservative and hostile to anything that deviated from orthodoxy. To this we must add that Darwin's approach violated the concept of nature hitherto recognized; so that by broad sectors of the church's reaction ware very aggressive. The discussions and publications on this subject have become especially visible on the occasion of the celebration, in 2009, the bicentennial of the birth of Charles Robert Darwin.

  6. Calcretes in the Thar desert: Genesis, chronology and ...

    Indian Academy of Sciences (India)

    R. Narasimhan (Krishtel eMaging) 1461 1996 Oct 15 13:05:22

    to Yaalon (1988) soils with secondary carbonate accumulations ..... The fraction over 500 µm constituted 6 to 8% of the sample and its absolute carbonate was less than 1%. .... However, if we take note of the uncertainty level of the estimate, an ...

  7. Genesis of magnetic fields in isolated white dwarfs

    Science.gov (United States)

    Briggs, Gordon P.; Ferrario, Lilia; Tout, Christopher A.; Wickramasinghe, Dayal T.

    2018-05-01

    A dynamo mechanism driven by differential rotation when stars merge has been proposed to explain the presence of strong fields in certain classes of magnetic stars. In the case of the high field magnetic white dwarfs (HFMWDs), the site of the differential rotation has been variously thought to be the common envelope, the hot outer regions of a merged degenerate core or an accretion disc formed by a tidally disrupted companion that is subsequently accreted by a degenerate core. We have shown previously that the observed incidence of magnetism and the mass distribution in HFMWDs are consistent with the hypothesis that they are the result of merging binaries during common envelope evolution. Here we calculate the magnetic field strengths generated by common envelope interactions for synthetic populations using a simple prescription for the generation of fields and find that the observed magnetic field distribution is also consistent with the stellar merging hypothesis. We use the Kolmogorov-Smirnov test to study the correlation between the calculated and the observed field strengths and find that it is consistent for low envelope ejection efficiency. We also suggest that field generation by the plunging of a giant gaseous planet on to a white dwarf may explain why magnetism among cool white dwarfs (including DZ white dwarfs) is higher than among hot white dwarfs. In this picture a super-Jupiter residing in the outer regions of the white dwarf's planetary system is perturbed into a highly eccentric orbit by a close stellar encounter and is later accreted by the white dwarf.

  8. The Genesis of a Trauma Performance Improvement Plan.

    Science.gov (United States)

    Pidgeon, Kristopher

    2015-01-01

    The purpose of this article is to assist the trauma medical and program director with developing a performance improvement and patients safety plan (PIPS), which is a required component of a successful trauma verification process by the American College of Surgeons. This article will review trauma quality standards and will describe in detail the required elements of a successful trauma center's performance improvement plan including a written comprehensive plan that outlines the mission and vision of the PIPS Program, authority of the PIPS Program, PIPS Program Committee reporting structure to the other hospital committees, list of required PIPS multidisciplinary team members, the operational components of the utilized data management system (trauma registry), list of indicators/audit filters, levels of review, peer determinations, corrective action plan with implementation, event resolution, and reevaluation. Strategies to develop a successful trauma performance improvement plan are presented.

  9. Compositional variation and genesis of ferromanganese crusts of ...

    Indian Academy of Sciences (India)

    incorporation of various metals in the Fe–Mn crusts ... shown to readily oxidize to their higher oxidation state on adsorption to ... metal species are those of the transition group com- ...... Banakar V K 1990 Uranium–thorium isotopes and tran-.

  10. Chromosomes in the genesis and progression of ependymomas

    DEFF Research Database (Denmark)

    Rogatto, S R; Casartelli, C; Rainho, C A

    1993-01-01

    chromosomes in three cases. Structural rearrangements of chromosome 2 were a finding for all cases and involved loss of material at 2q32-34. Other structural chromosome abnormalities detected involved chromosomes 4, 6, 10, 11, 12, and X. We also reviewed data on 22 cases previously reported....

  11. The paradoxical genesis of too-big-to-fail

    Directory of Open Access Journals (Sweden)

    Thomas S. Umlauft

    2014-03-01

    Full Text Available At least since the Global Financial Crisis of 2007-2009, the problem of too-big-to-fail (TBTF has received widespread attention. The research conducted in this context has, however, generally focused on the econometric aspect and the contribution of the TBTF doctrine to the financial crisis of 2007-2009, while the economic historical approach has been confined to tracing the doctrine to its first appearance. This paper attempts to fill this gap in the academic literature by offering an explanation for why, as opposed to how, the TBTF doctrine has developed. This paper identifies the US population’s distrust and at times hostility against the prospect of concentration of power in large financial institutions as the causal factor leading to the TBTF phenomenon. The resulting socially non-optimal regulation favoured a fragmented and fragile banking system based on small unit banks at the cost of more diversified branch banks. The Great Depression impressively highlighted the deep structural flaws of the US banking system. At the same time, however, it caused a shift in the public opinion, which had generally been opposed to deposit insurance, and thereby aligned the public interest with that of small banks, which would profit most from deposit insurance. The newly acquired public and political support enabled weak unit banks to lobby successfully against reforming the banking structure and instead for the adaption of federal deposit insurance. However, the Federal Deposit Insurance Corporation (FDIC only addressed the symptoms of the weak banking industry but not its causes. Moreover, the strongly biased FDIC policies have generally favoured creditors at large banks, which ultimately led to the TBTF doctrine which, in turn, provided banks with a non-technical incentive to grow in size in order to gain TBTF protection. Initially aimed at preserving the US financial landscape based on small unit banks, the FDIC as the main conduit for TBTF rescues thus became the main driver for big bank corporate welfare. Deposit insurance gave rise to TBTF and, at the same time, put small banks deemed “too-small-to-safe” at a competitive disadvantage, further accelerating the trend towards increasingly large and complex banks.

  12. Conclusion - Admixture elements as indicators of fluorite genesis

    International Nuclear Information System (INIS)

    Fayziev, A.R.

    2002-01-01

    The information obtained during scientific researches was generalized and analyzed. It was defined that studying of qualitative composition and quantitative content revealed the geochemical features of fluorite.

  13. Bricks as indicators for an urban soil genesis

    Science.gov (United States)

    Nehls, Thomas; Rokia, Sarah; Schwartz, Christophe; Wessolek, Gerd

    2013-04-01

    Bricks can be considered as anthropogenic markers since they are regularly found in urban soils worldwide. They are among the most resistent residues of building materials, therefore are called technogenic substrates. They have been dumped to urban soils since more than 4000 years and can be dated back to their burning using thermoluminescence. In Berlin, bricks have been piled up to more than 37 rubble mountains in the city after WW II. The devils mountain, the most prominent of them is higher than 60m. However, bricks are known not to be isolated in the soil but to fulfill soil functions due to their porosity. Therefore, they are nice research objects for soil scientists. The purpose of this study is to investigate abundance and functions of bricks in urban soils, focusing on plant nutrition and contamination aspects. Three different Berlin urban soils have been studied for their brick contents in the coarse and fine earth fractions by endless hand sorting. Light and scanning electron microscopy was then employed to investigate the bricks for proofs of plant roots. Third, CEC, pH, EC, Corg, nutrient storage (XRF) and availability (2:1 extract, ion chromatography, AAS) of bricks and fine earth fractions of the corresponding soil horizons have been investigated. The fine earth fractions of the investigated soils contain 3 to 5% of bricks, while the coarse fractions contain up to 50%. We found roots entering brick pores or at least attached to brick surfaces. Therefore, plants can use the water and nutrients stored in bricks. The CEC of bricks is grain size dependent and reaches a maximum of 6 cmolc kg-1 for particles smaller than 0.063 mm. This dependency is not explained by a low pore connectivity. Rather, it is the result of the restricted diffusion into the brick pore system due to the short shaking time in the CEC analysis protocol. From the nutrient storage and availabilities we conclude that bricks can better supply plants with K, Mg, Ca and S than the bulk soil at the investigated sandy site. However, in general, the nutrient availability from bricks is rather low compared to agricultural soils, except for Ca and S. Because of the water and nutrient storage, low contamination status and the possible rooting of bricks, they can be used for amelioration of poor sandy soils and for soil construction.

  14. Genesis of a Joint Gallery of Sport Art.

    Science.gov (United States)

    Kozar, Andrew J.

    1989-01-01

    The University of Pennsylvania's dual sport art gallery showcases the work of R. Taft McKenzie and Joe Brown, two of the premier sport artists of our time. This article briefly outlines the artists' careers and describes the planning which led to establishment of the gallery. (IAH)

  15. Contributions to the Genesis and Progress of ICF

    Energy Technology Data Exchange (ETDEWEB)

    Nuckolls, J H

    2006-02-15

    Inertial confinement fusion (ICF) has progressed from the detonation of large-scale fusion explosions initiated by atomic bombs in the early 1950s to final preparations for initiating small-scale fusion explosions with giant lasers. The next major step after ignition will be development of high performance targets that can be initiated with much smaller, lower cost lasers. In the 21st century and beyond, ICF's grand challenge is to develop practical power plants that generate low cost, clean, inexhaustible fusion energy. In this chapter, I first describe the origin in 1960-61 of ICF target concepts, early speculations on laser driven 'Thermonuclear Engines' for power production and rocket propulsion, and encouraging large-scale nuclear explosive experiments conducted in 1962. Next, I recall the 40-year, multi-billion dollar ignition campaign - to develop a matched combination of sufficiently high-performance implosion lasers and sufficiently stable targets capable of igniting small fusion explosions. I conclude with brief comments on the NIF ignition campaign and very high-performance targets, and speculations on ICF's potential in a centuries-long Darwinian competition of future energy systems. My perspectives in this chapter are those of a nuclear explosive designer, optimistic proponent of ICF energy, and Livermore Laboratory leader. The perspectives of Livermore's post 1970 laser experts and builders, and laser fusion experimentalists are provided in a chapter written by John Holzrichter, a leading scientist and leader in Livermore's second generation laser fusion program. In a third chapter, Ray Kidder, a theoretical physicist and early laser fusion pioneer, provides his perspectives including the history of the first generation laser fusion program he led from 1962-1972.

  16. Nonlinear morphoelastic plates I: Genesis of residual stress

    KAUST Repository

    McMahon, J.; Goriely, A.; Tabor, M.

    2011-01-01

    Volumetric growth of an elastic body may give rise to residual stress. Here a rigorous analysis is given of the residual strains and stresses generated by growth in the axisymmetric Kirchhoff plate. Balance equations are derived via the Global Constraint Principle, growth is incorporated via a multiplicative decomposition of the deformation gradient, and the system is closed by a response function. The particular case of a compressible neo-Hookean material is analyzed, and the existence of residually stressed states is established. © SAGE Publications 2011.

  17. Genesis: A Framework for Achieving Software Component Diversity

    Science.gov (United States)

    2007-01-01

    correctly—the initial filters develop to fix the Hotmail vulnerability could be circumvented by using alternate character encodings4. Hence, we focus on...Remotely Exploitable Cross-Site Scripting in Hotmail and Yahoo, (March 2004); http://www.greymagic.com/security/advisories/gm005-mc/. 4...EyeonSecurity, Microsoft Passport Account Hijack Attack: Hacking Hotmail and More, Hacker’s Digest. 5. Y.-W. Huang et al., Web Application Security Assessment by

  18. INITIAL STAGES OF CARBON GENESIS IN THE UNIVERSE

    Directory of Open Access Journals (Sweden)

    A.L. Vereshchagin

    2004-12-01

    Full Text Available The formation possibility of the most widespread carbon compounds had been showed on the base of detonation nanodiamonds thermodynamic data. These reactions may play a key role in the life origin and in the atmosphere formation of the Solar system giant planets

  19. From lepton protoplasm to the genesis of hadrons

    Science.gov (United States)

    Eliseev, S. M.; Kosmachev, O. S.

    2016-01-01

    Theory of matter under extreme conditions opens a new stage in particle physics. It is necessary here to combine Dirac's elementary particle physics with Prigogine's dynamics of nonequilibrium systems. In the article we discuss the problem of the hierarchy of complexity. What can be considered as the lowest level of the organization of extreme matter on the basis of which the self-organization of the complex form occur?

  20. Contributions to the Genesis and Progress of ICF

    International Nuclear Information System (INIS)

    Nuckolls, J.H.

    2006-01-01

    Inertial confinement fusion (ICF) has progressed from the detonation of large-scale fusion explosions initiated by atomic bombs in the early 1950s to final preparations for initiating small-scale fusion explosions with giant lasers. The next major step after ignition will be development of high performance targets that can be initiated with much smaller, lower cost lasers. In the 21st century and beyond, ICF's grand challenge is to develop practical power plants that generate low cost, clean, inexhaustible fusion energy. In this chapter, I first describe the origin in 1960-61 of ICF target concepts, early speculations on laser driven 'Thermonuclear Engines' for power production and rocket propulsion, and encouraging large-scale nuclear explosive experiments conducted in 1962. Next, I recall the 40-year, multi-billion dollar ignition campaign - to develop a matched combination of sufficiently high-performance implosion lasers and sufficiently stable targets capable of igniting small fusion explosions. I conclude with brief comments on the NIF ignition campaign and very high-performance targets, and speculations on ICF's potential in a centuries-long Darwinian competition of future energy systems. My perspectives in this chapter are those of a nuclear explosive designer, optimistic proponent of ICF energy, and Livermore Laboratory leader. The perspectives of Livermore's post 1970 laser experts and builders, and laser fusion experimentalists are provided in a chapter written by John Holzrichter, a leading scientist and leader in Livermore's second generation laser fusion program. In a third chapter, Ray Kidder, a theoretical physicist and early laser fusion pioneer, provides his perspectives including the history of the first generation laser fusion program he led from 1962-1972.

  1. Genesis of unified models from Majorana-Weyl fields

    International Nuclear Information System (INIS)

    Budini, P.; Furlan, P.

    1977-07-01

    It is proposed that all forms of interaction arise from elementary interactions between Weyl-Majorana fields. Weak interactions due to the high masses of the intermediate bosons are practically identical to the elementary interactions. Strong and electromagnetic interactions arise at larger distance, where dynamic determines both masses and symmetry. In the frame of these ideas, Pati-Salam and Fritzsch-Minkowski type of unified models are constructed starting from eight Weyl-Majorana fields. Fractional charges for quarks, integer charges for lepton and regularization of q.e.d. arise naturally from the model. Unobserved transitions (μ→e + γ, p→ leptons) may be ascribed to properties of the elementary fields (handedness) rather than very high W masses

  2. On spinor geometry: A genesis of extended supersymmetry

    International Nuclear Information System (INIS)

    Budini, P.

    1980-08-01

    It is conjectured that euclidean geometry should be derived from spinor geometry through the equivalence of simple semispinor with isotropic semi n-vectors. The only tensors of complex 2n dimensional Euclidean space Esub(c)sup(2n) should then be: isotropic n - vectors and their intersections. Esub(c) 4 spinor geometry generates two isotropic semi bivectors equivalent to the semispinors of Esub(c) 4 (their geometrical properties are those of light propagating in vacuum), and their intersection: an isotropic vector (possibly representing momenta of massless particle and/or light rays); but no scalar, pseudoscalar or pseudovector is generated. In order to generate vectors outside the light cone in Msup(3.1) one needs not less than Esub(c) 6 spinor geometry which also generates Lorentz pseudoscalars and non isotropic pseudovectors and tensors. Besides, Dirac spinor should then always appear in doublets in Msup(3.1). Furthermore the mere geometrical structure of Esub(c) 6 spinor geometry seems to suggest formally, both Poincare (extended) and conformal supersymmetry. The suggested spinor-geometrical approach privileges the elementary role of semispinors. Its relevance for the real world should be manifested by the privileged role of semispinors in elementary interactions as in fact seems to be the case with Lorentz semispinors in weak interactions (and could perhaps also be the case for strong ones where conformal semispinors (or twistors) could be the interacting spinor fields). (author)

  3. High-resolution seismic studies on geothermal heat extraction from low, permeable rock strata in the city of Hanover using depth-dependent, optimized acquisition parameters; Hochaufloesende seismische Untersuchungen zur Erdwaermegewinnung aus tiefen, permeablen Gesteinsformationen im Stadtgebiet Hannover unter Verwendung von Profilen mit teufenabhaengig optimierten Akquisitionsparametern

    Energy Technology Data Exchange (ETDEWEB)

    Thomas, R. [GGA-Inst. fuer Geowissenschaftliche Gemeinschaftsaufgaben, Hannover (Germany)

    2002-07-01

    The investigations accompanied a demonstration project on geothermal heat production planned by GEOZENTRUM, Hanover, in which geothermal heat will be produced from muschelkalk and mottled sandstone in the area of Hanover/Misburg by means of ''generated geothermal systems'' (GeneSys). This involves detailed seismic exploration of the geological strata of all depth levels. Profile data of the Thoense gas field will be integrated. [German] Die Untersuchungen stehen im Zusammenhang mit dem vom GEOZENTRUM-Hannover geplanten Demonstrationsvorhaben zur Erdwaermegewinnung mittels ''Generierter geothermischer Energie Systeme'' (GeneSys) im Stadtgebiet Hannover/Misburg. Zielhorizonte sind der Muschelkalk und der Buntsandstein. Dazu sollten die geologischen Strukturen im gesamten Teufenbereich detailliert seismisch erkundet werden, wobei neben neuen Messungen auch die vorliegenden Informationen aus bereits gemessenen Profilen des Gasfeldes Thoense einfliessen. (orig.)

  4. Biogas and BioFertilizer Production Using Green Technology

    International Nuclear Information System (INIS)

    Sirirote, Pramote

    2010-01-01

    Basically, it is technology which created and used in a way that conserves natural resources and the environment. This technology also can be environmental friendly because the use of this technology is supposed to reduce the amount of waste and pollution that is created during production and consumption. These food wastes will come from animal bone, crab skeleton, fish skeleton, rice, noodle, vegetable and others. We collect all of these wastes and then keep it in plants, and then we make sure that this waste will turn into biogas via anaerobic digestion. All of these involved hydrolysis, fermentation, aceto genesis and methano genesis process. Methane that produced will be used in biomass plant to generate electricity. Meanwhile bio fertilizer that produced will be applied on agriculture sectors as fertilizer for plants.

  5. Genesis of B lymphocytes in the bone marrow: extravascular and intravascular localization of surface IgM-bearing cells in mouse bone marrow detected by electron-microscope radioautography after in vivo perfusion of 125I anti-IgM antibody

    International Nuclear Information System (INIS)

    Osmond, D.G.; Batten, S.J.

    1984-01-01

    The role of mammalian bone marrow in generating surface IgM (sIgM)-bearing B lymphocytes is reviewed. Precursor cells in the marrow give rise to large, rapidly dividing cells bearing free cytoplasmic mu chains (c mu). The progeny of the large c mu+ cells form a population of small, nondividing c mu+ cells that mature into small lymphocytes, progressively expressing sIgM and other B-cell surface membrane components. Newly formed sIgM+ cells soon migrate through the bloodstream to the spleen and other lymphoid tissues, where they may die after a short lifespan or be activated to produce antibody molecules. The large-scale lymphocytopoiesis in the bone marrow thus maintains a population of rapidly renewed virgin B lymphocytes in the peripheral lymphoid tissues. A technique for perfusing radiolabeled anti-IgM antibodies in young mice has now permitted sIgM+ cells to be detected radioautographically in histological preparations of bone marrow under the electron microscope. Small sIgM+ lymphocytes are situated either singly or in small groups throughout the extravascular hemopoietic compartment of the bone marrow, often near sinusoid walls adjacent to late erythroblasts and reticular cells. Some regional concentrations of sIgM+ cells are apparent. sIgM+ cells also appear in transit through the sinusoidal endothelium and are markedly concentrated in the lumen of some sinusoids. Intrasinusoidal sIgM+ small lymphocytes have high densities of sIgM and long microvilli, on which sIgM molecules are concentrated. These studies reveal the localization and cell associations of specifically identified sIgM+ small lymphocytes in the extravascular marrow compartment and suggest that these cells may also undergo a transient intravascular storage and maturation phase. Use of this in vivo immunolabeling technique to detect other cell-surface markers may further elucidate the microenvironmental basis of B lymphocyte genesis in the bone marrow

  6. Clinical evaluation of a novel dental implant system as single implants under immediate loading conditions - 4-month post-loading results from a multicentre randomised controlled trial.

    Science.gov (United States)

    Esposito, Marco; Trullenque-Eriksson, Anna; Blasone, Rodolfo; Malaguti, Giuliano; Gaffuri, Cristiano; Caneva, Marco; Minciarelli, Armando; Luongo, Giuseppe

    To evaluate the safety and clinical effectiveness of a novel dental implant system (GENESIS Implant System, Keystone Dental, Massachusetts, USA) using another dental implant system by the same manufacturer as a control (PRIMA Implant System, Keystone Dental). A total of 53 patients requiring at least two single crowns had their sites randomised according to a split-mouth design to receive both implant systems at six centres. If implants could be placed with a torque superior to 40 Ncm they were to be loaded immediately with provisional crowns, otherwise after 3 months of submerged healing. Provisional crowns were replaced by definitive crowns 4 months after initial loading, when the follow-up period for the initial part of this study was completed. Outcome measures were crown/implant failures, complications, pink esthetic score (PES), peri-implant marginal bone level changes, plaque score, marginal bleeding, patients and preference of the clinician. In total 53 PRIMA and 53 GENESIS implants were placed. Three patients dropped out but all of the remaining patients were followed up to 4-months post-loading. No PRIMA implant failed whereas four GENESIS implants failed. Only two complications were reported for PRIMA implants. There were no statistically significant differences for crown/implant failures (difference in proportions = 0.080; P (McNemar test) = 0.125) and complications (difference in proportions = -0.04; P (McNemar test) = 0.500) between the implant systems. There were no differences at 4-months post-loading for plaque (difference = -0.54, 95% CI: -3.01 to 1.93; P (Paired t-test) = 0.660), marginal bleeding (difference = -3.8, 95% CI: -7.63 to 0.019; P (Paired t-test) = 0.051), PES (difference = 0.47, 95% CI: -0.56 to 1.50; P (Paired t-test) = 0.365) and marginal bone level changes (difference in mm = -0.04, 95% CI: -0.33 to 0.26; P (Paired t-test) = 0.795). The majority of the patients (46) had no

  7. National Library of Medicine Celebrates 30 Years of Progress and Charts the Future | NIH MedlinePlus the Magazine

    Science.gov (United States)

    ... described the genesis of the National Center for Biotechnology Information (NCBI); the Visible Human Project (a digital ... expand the publication and distribution of NIH MedlinePlus magazine, thousands and thousands more people will gain valuable, ...

  8. The role of mid-level vortex in the intensification and weakening of ...

    Indian Academy of Sciences (India)

    Govindan Kutty

    2017-10-06

    Oct 6, 2017 ... the importance of such vortex developments in the intensification of tropical cyclone. The genesis ... ing a thermodynamically favourable environment to facilitate .... zontal extension, intensity and organization of PV at both the ...

  9. E2F5 status significantly improves malignancy diagnosis of epithelial ovarian cancer

    KAUST Repository

    Kothandaraman, Narasimhan; Bajic, Vladimir B.; Brendan, Pang NK; Huak, Chan Y; Keow, Peh B; Razvi, Khalil; Salto-Tellez, Manuel; Choolani, Mahesh

    2010-01-01

    Background: Ovarian epithelial cancer (OEC) usually presents in the later stages of the disease. Factors, especially those associated with cell-cycle genes, affecting the genesis and tumour progression for ovarian cancer are largely unknown. We

  10. Study of genesis in Qahr-Abad fluorite deposit using fluid inclusion, southeast of Saqqez, the Kurdistan province

    Directory of Open Access Journals (Sweden)

    Mehrdad Barati

    2017-07-01

    . Discussion Thermometric investigations indicate that homogenization temperatures for primary and pseudo secondary fluid inclusions in all fluorite types range from 155 to 245°C with an average of 187°C. Gas phase changes to liquid phase in the homogenization processes. The degree of fillings in most inclusions are more than 90%. -23 to -18 °C with an average of -20.7°C. There are eutectic temperatures in the freezing method and calculated salinity is 30.8 wt% NaCl equivalents in terms of the H2O-CO2-NaCl system. The Bernoulli Effect has occurred in this resource (Barnes, 1998. Isothermal mixing, boiling, surface fluid dilution and depressurization are four processes that have effects on the mineralization in this resource (Wilkinson, 2001. Finally we think, Qahr -abad fluorite deposit has been prepared by hydrothermal to epithermal processes and fluids have basin origin (fossil waters (Tajoddyn, et al, 2010 and the orebody has precipitated from this fluid, when it was mixed with cold surface waters. References Barnes, H.L., 1998. Geochemistry of hydrothermal ore deposits. John Wiley & Sons, Malaysia, 972 pp. Kholghi Khasraghi, M.H., 1999. Geological map of Irankhah. Scale 1:100,000. Geological Survey of Iran. Moslehi, M., 2013. The study of fluid inclusion and geochemistry of Qahr-Abad Soliman deposit in Kurdistan province. M.Sc. Thesis, Bu-Ali Sina University, Hamedan, Iran, 142 pp. (in Persian with English abstract Tajoddyn, H., Rastad, A., Yaghobpour, A. and Mohajel, M., 2010. The genesis of Barica Gold massive sulfide deposit, east of Sardasht, NW of metamorphic Sanandaj –Sirjan zone base on structure, texture and micro thermometric studies. Journal of Economic Geology, 2(1: 97-118. (in Persian Talaii, B., 2010. The study of mineralogy and geochemistry of Qahr-Abad fluorite deposit, SE of Sagez city, Kurdistan province. M.Sc. Thesis, University of Uromieh, Uromieh, Iran, 119 pp. (in Persian with English abstract Wilkinson, J.J., 2001. Fluid inclusions in

  11. Mixed clusters from the coexpansion of C2F6 and n2 in a pulsed, supersonic expansion cluster ion source and beam deflection time-of-flight mass spectrometer: A first application

    Science.gov (United States)

    Thompson, Steven D.

    The following topics are discussed: (1) cluster ion genesis; (2) cluster ion detection; (3) Ion source; (4) pulse valve; (5) e-gun; (6) Ion optics; (7) a first order model; and (8) a modified Bakker's model.

  12. Salivary gland enlargement during oesophageal stricture dilatation.

    OpenAIRE

    Martin, D.

    1980-01-01

    A case of recurrent salivary gland enlargement occurring during fibreoptic oesophagoscopy and oesophageal stricture dilatation with Eder-Puestow dilators is described. The genesis of this condition is discussed and its transient and usually benign nature emphasized.

  13. RSOI: Force Deployment Bottleneck

    National Research Council Canada - National Science Library

    D'Amato, Mark

    1998-01-01

    .... This runs counter to the popular belief that strategic lift is the limiting constraint. The study begins by highlighting the genesis of the military's current force projection strategy and the resulting importance of rapid force deployments...

  14. U-Pb isotope systematics and compared evolution of uraniferous mineralizations in the Athabasca basin (Saskatchewan, Canada): Case of deposits from the Carswell and Cigar Lake structure

    International Nuclear Information System (INIS)

    Philippe, S.

    1988-01-01

    The aim of the study is to obtain geochronologic data on the formation of mineralizations, to define main processes for uranium remobilization and to replace these data in proposed model for deposit genesis and evolution [fr

  15. [Sanation of biliary system using antiseptic decasan in complex treatment of cholangitis].

    Science.gov (United States)

    Aripova, N U; Magzumov, I Kh

    2014-02-01

    Experience of treatment of 17 patients, suffering cholangitis of various genesis, using antiseptic Decasan, is presented. Clinical efficacy of the preparation in complex treatment of cholangitis, confirmed by results of the bile bacteriological investigation, was noted.

  16. Emerging trends in disaster management and the Ethiopian ...

    African Journals Online (AJOL)

    Emerging trends in disaster management and the Ethiopian experience: genesis, reform and transformation. ... Journal of Business and Administrative Studies ... Key words: disaster management, drought, pre-disaster action, post-disaster action, hazards, disaster, Ethiopian disaster management system, Ethiopia.

  17. Structure and evolution of the Afanasy Nikitin seamount, buried hills and 85 degrees E Ridge in the northeastern Indian Ocean

    Digital Repository Service at National Institute of Oceanography (India)

    Krishna, K.S.

    Geophysical data of the Afanasy Nikitin seamount (ANS), partly buried hills and 85 degrees E Ridge in the northeastern Indian Ocean were studied together with published seismic refraction results to understand genesis and evolution of the structures...

  18. Note in materia di scioglimento del matrimonio civile non consumato

    Directory of Open Access Journals (Sweden)

    Simone Baldetti

    2014-11-01

    Full Text Available Contributo sottoposto a valutazioneSOMMARIO: 1. Premessa – 2 Genesi parlamentare - 3. Nozione di inconsumazione – 4. Inquadramento dell’istituto nel sistema matrimoniale civile – 5. Aspetti processuali - 6. Giurisprudenza italiana e dispensa pontificia.

  19. Intramitochondrial autonomy in rat tissues

    International Nuclear Information System (INIS)

    Subramanian, M.; Rajwade, M.S.; Satav, J.G.; Katyare, S.S.; Fatterpaker, P.; Sreenivasan, A.

    1974-01-01

    The biogenesis of mitochondria in rat liver and their protein turnover has been investigated using 1- 14 C leucine. The results indicate that intramitochondrial autonomy exists both with respect to their genesis and turnover. (M.G.B.)

  20. The evolution of scientific views on strategic financial planning abroad

    OpenAIRE

    Vorobyev Alexey Vyacheslavovich

    2012-01-01

    This article deals with the genesis of scientific views on strategic financial planning abroad. The allocation process of strategic planning of functional strategies, particularly financial. Given the systematization of conceptual approaches to strategic financial planning within evolution.

  1. Tartu Ülikooli teadur kaitses Cambridgeì Ülikoolis doktorikraadi / Krõõt Nõges

    Index Scriptorium Estoniae

    Nõges, Krõõt

    2006-01-01

    Tartu Ülikooli filosoofia osakonna teadur ja eetikakeskuse stipendiaat Eva Piirimäe kaitses Cambridgeì Ülikoolis doktorikraadi ideede ajaloo erialal doktoritööga "Thomas Abbt (1738-1766) and the Philosophical Genesis of German Nationalism"

  2. Pop / Tõnis Kahu

    Index Scriptorium Estoniae

    Kahu, Tõnis, 1962-

    2005-01-01

    Heliplaatidest: Angelo Badalamenti "AVery Long Engagement", Kyo Ichinose "Lontano", Jah Wobble "I Could Have Been A Contender", Jah Wobble "Elevator Music Volume 1A", Yulduz "Bilmadim", Genesis "Platinum Collection", Durutti Column "The Best of the Durutti Column"

  3. On the origin of spurious errors in many-body expansion for water ...

    Indian Academy of Sciences (India)

    SOUMEN SAHA

    lized in various significant methodological approaches. However, since ..... CSIR, New Delhi is thanked for financial support in the form of GENESIS (BSC-121), a 12th five year Plan project. GNS .... II. accuracy considerations J. Chem. Phys.

  4. Standardless quantification by parameter optimization in electron probe microanalysis

    International Nuclear Information System (INIS)

    Limandri, Silvina P.; Bonetto, Rita D.; Josa, Víctor Galván; Carreras, Alejo C.; Trincavelli, Jorge C.

    2012-01-01

    A method for standardless quantification by parameter optimization in electron probe microanalysis is presented. The method consists in minimizing the quadratic differences between an experimental spectrum and an analytical function proposed to describe it, by optimizing the parameters involved in the analytical prediction. This algorithm, implemented in the software POEMA (Parameter Optimization in Electron Probe Microanalysis), allows the determination of the elemental concentrations, along with their uncertainties. The method was tested in a set of 159 elemental constituents corresponding to 36 spectra of standards (mostly minerals) that include trace elements. The results were compared with those obtained with the commercial software GENESIS Spectrum® for standardless quantification. The quantifications performed with the method proposed here are better in the 74% of the cases studied. In addition, the performance of the method proposed is compared with the first principles standardless analysis procedure DTSA for a different data set, which excludes trace elements. The relative deviations with respect to the nominal concentrations are lower than 0.04, 0.08 and 0.35 for the 66% of the cases for POEMA, GENESIS and DTSA, respectively. - Highlights: ► A method for standardless quantification in EPMA is presented. ► It gives better results than the commercial software GENESIS Spectrum. ► It gives better results than the software DTSA. ► It allows the determination of the conductive coating thickness. ► It gives an estimation for the concentration uncertainties.

  5. Predicting Tropical Cyclogenesis with a Global Mesoscale Model: Preliminary Results with Very Severe Cyclonic Storm Nargis (2008)

    Science.gov (United States)

    Shen, B.; Tao, W.; Atlas, R.

    2008-12-01

    Very Severe Cyclonic Storm Nargis, the deadliest named tropical cyclone (TC) in the North Indian Ocean Basin, devastated Burma (Myanmar) in May 2008, causing tremendous damage and numerous fatalities. An increased lead time in the prediction of TC Nargis would have increased the warning time and may therefore have saved lives and reduced economic damage. Recent advances in high-resolution global models and supercomputers have shown the potential for improving TC track and intensity forecasts, presumably by improving multi-scale simulations. The key but challenging questions to be answered include: (1) if and how realistic, in terms of timing, location and TC general structure, the global mesoscale model (GMM) can simulate TC genesis and (2) under what conditions can the model extend the lead time of TC genesis forecasts. In this study, we focus on genesis prediction for TCs in the Indian Ocean with the GMM. Preliminary real-data simulations show that the initial formation and intensity variations of TC Nargis can be realistically predicted at a lead time of up to 5 days. These simulations also suggest that the accurate representations of a westerly wind burst (WWB) and an equatorial trough, associated with monsoon circulations and/or a Madden-Julian Oscillation (MJO), are important for predicting the formation of this kind of TC. In addition to the WWB and equatorial trough, other favorable environmental conditions will be examined, which include enhanced monsoonal circulation, upper-level outflow, low- and middle-level moistening, and surface fluxes.

  6. Large scale features and energetics of the hybrid subtropical low `Duck' over the Tasman Sea

    Science.gov (United States)

    Pezza, Alexandre Bernardes; Garde, Luke Andrew; Veiga, José Augusto Paixão; Simmonds, Ian

    2014-01-01

    New aspects of the genesis and partial tropical transition of a rare hybrid subtropical cyclone on the eastern Australian coast are presented. The `Duck' (March 2001) attracted more recent attention due to its underlying genesis mechanisms being remarkably similar to the first South Atlantic hurricane (March 2004). Here we put this cyclone in climate perspective, showing that it belongs to a class within the 1 % lowest frequency percentile in the Southern Hemisphere as a function of its thermal evolution. A large scale analysis reveals a combined influence from an existing tropical cyclone and a persistent mid-latitude block. A Lagrangian tracer showed that the upper level air parcels arriving at the cyclone's center had been modified by the blocking. Lorenz energetics is used to identify connections with both tropical and extratropical processes, and reveal how these create the large scale environment conducive to the development of the vortex. The results reveal that the blocking exerted the most important influence, with a strong peak in barotropic generation of kinetic energy over a large area traversed by the air parcels just before genesis. A secondary peak also coincided with the first time the cyclone developed an upper level warm core, but with insufficient amplitude to allow for a full tropical transition. The applications of this technique are numerous and promising, particularly on the use of global climate models to infer changes in environmental parameters associated with severe storms.

  7. Corticosterone rapidly increases thorns of CA3 neurons via synaptic/extranuclear glucocorticoid receptor in rat hippocampus

    Directory of Open Access Journals (Sweden)

    Miyuki eYoshiya

    2013-11-01

    Full Text Available Modulation of synapses under acute stress is attracting much attention. Exposure to acute stress induces corticosterone (CORT secretion from the adrenal cortex, resulting in rapid increase of CORT levels in plasma and the hippocampus. We tried to test whether rapid CORT effects involve activation of essential kinases as non-genomic processes.We demonstrated rapid effects (~ 1 h of CORT on the density of thorns, by imaging Lucifer Yellow-injected neurons in adult male rat hippocampal slices. Thorns of thorny excrescences of CA3 hippocampal neurons are post-synaptic regions whose presynaptic partners are mossy fiber terminals. The application of CORT at 100, 500 and 1000 nM induced a rapid increase in the density of thorns in the stratum lucidum of CA3 pyramidal neurons. Co-administration of RU486, an antagonist of glucocorticoid receptor (GR, abolished the effect of CORT. Blocking a single kinase, including MAPK, PKA or PKC, suppressed CORT-induced enhancement of thorn-genesis. On the other hand, GSK-3β was not involved in the signaling of thorn-genesis. Blocking AMPA receptors suppressed the CORT effect. Expression of CA3 synaptic/extranuclear GR was demonstrated by immunogold electron microscopic analysis. From these results, stress levels of CORT (100-1000 nM might drive the rapid thorn-genesis via synaptic/extranuclear GR and multiple kinase pathways, although a role of nuclear GRs cannot be completely excluded.

  8. Pdgfrb-Cre targets lymphatic endothelial cells of both venous and non-venous origins.

    Science.gov (United States)

    Ulvmar, Maria H; Martinez-Corral, Ines; Stanczuk, Lukas; Mäkinen, Taija

    2016-06-01

    The Pdgfrb-Cre line has been used as a tool to specifically target pericytes and vascular smooth muscle cells. Recent studies showed additional targeting of cardiac and mesenteric lymphatic endothelial cells (LECs) by the Pdgfrb-Cre transgene. In the heart, this was suggested to provide evidence for a previously unknown nonvenous source of LECs originating from yolk sac (YS) hemogenic endothelium (HemEC). Here we show that Pdgfrb-Cre does not, however, target YS HemEC or YS-derived erythro-myeloid progenitors (EMPs). Instead, a high proportion of ECs in embryonic blood vessels of multiple organs, as well as venous-derived LECs were targeted. Assessment of temporal Cre activity using the R26-mTmG double reporter suggested recent occurrence of Pdgfrb-Cre recombination in both blood and lymphatic ECs. It thus cannot be excluded that Pdgfrb-Cre mediated targeting of LECs is due to de novo expression of the Pdgfrb-Cre transgene or their previously established venous endothelial origin. Importantly, Pdgfrb-Cre targeting of LECs does not provide evidence for YS HemEC origin of the lymphatic vasculature. Our results highlight the need for careful interpretation of lineage tracing using constitutive Cre lines that cannot discriminate active from historical expression. The early vascular targeting by the Pdgfrb-Cre also warrants consideration for its use in studies of mural cells. genesis 54:350-358, 2016. © 2016 The Authors. Genesis Published by Wiley Periodicals, Inc. © 2016 The Authors. Genesis Published by Wiley Periodicals, Inc.

  9. Shoreline changes in and around the Thubon River mouth, Central Vietnam

    Digital Repository Service at National Institute of Oceanography (India)

    Mau, L.D.; Nayak, G.N.; SanilKumar, V.

    Application of GENESIS model (GENEralized model for Simulating Shoreline change) for studying the shoreline change in and around the Thubon River Mouth, Central Vietnam is presented in this paper The input parameters used are the near shore wave...

  10. Special Relativity and the Michelson-Morley Experiment.

    Science.gov (United States)

    Chapman, Bryan R.

    1979-01-01

    Presents selective and representative evidence relating to the genesis of the theory of special relativity. The evidence seems to defy most of the philosophic preconceptions which many physics teachers appear to have about the nature of physics. (GA)

  11. Regeneration and resurrection in Matthew – Peasants in campo ...

    African Journals Online (AJOL)

    2010-12-10

    Dec 10, 2010 ... University of Pretoria, South ... These concepts lead to Matthew's reading3: 1. .... The idea of the kingdom of God can be viewed as an apocalyptic alternative to ... Matthew completes a circular movement when his 'genesis'.

  12. Resonance – Journal of Science Education | Indian Academy of ...

    Indian Academy of Sciences (India)

    Articles written in Resonance – Journal of Science Education. Volume 7 Issue 6 June ... Introduction to Web Information Retrieval: A User Perspective - How to get what you want on the World Wide Web ... UNIX: Genesis and Design Features.

  13. One hundred years of the Journal of Genetics

    Indian Academy of Sciences (India)

    The Journal of Genetics completed a hundred years this November, having thereby lived ... made possible by the tremendous advances in genetics over the past one hundred years—refocusses attention on the key question of the genesis and ...

  14. Modeling of anaerobic digestion of complex substrates

    International Nuclear Information System (INIS)

    Keshtkar, A. R.; Abolhamd, G.; Meyssami, B.; Ghaforian, H.

    2003-01-01

    A structured mathematical model of anaerobic conversion of complex organic materials in non-ideally cyclic-batch reactors for biogas production has been developed. The model is based on multiple-reaction stoichiometry (enzymatic hydrolysis, acidogenesis, aceto genesis and methano genesis), microbial growth kinetics, conventional material balances in the liquid and gas phases for a cyclic-batch reactor, liquid-gas interactions, liquid-phase equilibrium reactions and a simple mixing model which considers the reactor volume in two separate sections: the flow-through and the retention regions. The dynamic model describes the effects of reactant's distribution resulting from the mixing conditions, time interval of feeding, hydraulic retention time and mixing parameters on the process performance. The model is applied in the simulation of anaerobic digestion of cattle manure under different operating conditions. The model is compared with experimental data and good correlations are obtained

  15. There is no gap 'per se' between theory and practice

    DEFF Research Database (Denmark)

    Larsen, Kristian; Adamsen, Lis; Bjerregaard, Lene Berit Skov

    2003-01-01

    The aim of this article is to highlight relations between theory and practice and the genesis of professional action in clinical nursing and among researchers. With use of a sociologically based empirical approach, focus is placed on the knowledge involved in the work of researchers and practitio...... nurses are inspired and learn from the context, including each other, and they are active producers of knowledge, not simply recipients of knowledge. This study, therefore, claims that there is no research-practice gap “in itself” (per se) as argued in the “barriers paradigm.”......The aim of this article is to highlight relations between theory and practice and the genesis of professional action in clinical nursing and among researchers. With use of a sociologically based empirical approach, focus is placed on the knowledge involved in the work of researchers...

  16. Geochemistry and petrogenesis of anorogenic basic volcanic ...

    Indian Academy of Sciences (India)

    R. Narasimhan (Krishtel eMaging) 1461 1996 Oct 15 13:05:22

    The Kundal area of Malani Igneous Suite consists of volcano-plutonic rocks. Basalt flows ...... genesis of lavas erupted along the south west Indian ridge between the ... Schilling J G 1966 Rare earth fractionation in Hawaiian vol- canic rocks ...

  17. Orchidectomy and oestrogen therapy revisited

    DEFF Research Database (Denmark)

    Iversen, P

    1998-01-01

    with gynaecomastia, loss of sexual function and unacceptable cardiovascular toxicity. Low dose oestrogens in combination with antiandrogens or antithrombotic agents may be better tolerated treatments. The route of administration is a crucial factor in the genesis of cardiovascular toxicity and parenterally...

  18. The evolution of scientific views on strategic financial planning abroad

    Directory of Open Access Journals (Sweden)

    Vorobyev Alexey Vyacheslavovich

    2012-09-01

    Full Text Available This article deals with the genesis of scientific views on strategic financial planning abroad. The allocation process of strategic planning of functional strategies, particularly financial. Given the systematization of conceptual approaches to strategic financial planning within evolution.

  19. (ethylene terephthalate) biomimetic composites

    Indian Academy of Sciences (India)

    In vitro bioactivity of the HAp/PEA-co-PET composites was studied by soaking in simulated .... 2.2d Characterization of cyclic oligomers: The C-OEA, ... GENESIS2000, EDAX) for microanalysis. ... Both spectra did not show the signal of end.

  20. METHYLENE BLUE ADSORPTION FROM GLYCEROL SOLUTION ...

    African Journals Online (AJOL)

    Preferred Customer

    The recognition of the presence of two habits of goethite was indicated by. Atkinson et ... The growth of certain face may be preferred over the other and the ... A Genesis II Fourier Transform infrared spectrometer was used to record the spectra.