WorldWideScience

Sample records for general studies latest

  1. Chemical and biological warfare: General studies. (Latest citations from the NTIS bibliographic database). Published Search

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-10-01

    The bibliography contains citations concerning federally sponsored and conducted studies into chemical and biological warfare operations and planning. These studies cover areas not addressed in other parts of this series. The topics include production and storage of agents, delivery techniques, training, military and civil defense, general planning studies, psychological reactions to chemical warfare, evaluations of materials exposed to chemical agents, and studies on banning or limiting chemical warfare. Other published searches in this series on chemical warfare cover detection and warning, defoliants, protection, and biological studies, including chemistry and toxicology. (Contains 50-250 citations and includes a subject term index and title list.) (Copyright NERAC, Inc. 1995)

  2. Chemical and biological warfare: General studies. (Latest citations from the NTIS bibliographic database). Published Search

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-11-01

    The bibliography contains citations concerning federally sponsored and conducted studies into chemical and biological warfare operations and planning. These studies cover areas not addressed in other parts of this series. The topics include production and storage of agents, delivery techniques, training, military and civil defense, general planning studies, psychological reactions to chemical warfare, evaluations of materials exposed to chemical agents, and studies on banning or limiting chemical warfare. Other published searches in this series on chemical warfare cover detection and warning, defoliants, protection, and biological studies, including chemistry and toxicology.(Contains 50-250 citations and includes a subject term index and title list.) (Copyright NERAC, Inc. 1995)

  3. Ground water pollution: General studies. (Latest citations from the NTIS bibliographic database). Published Search

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-05-01

    The bibliography contains citations concerning sources, contaminant transport, and monitoring of pollutants in aquifers. Topics include pollution characterization from landfills and mine drainage, descriptions of study programs undertaken by specific states, and Superfund site studies of contaminated areas. The uses of mathematical models are also discussed. (Contains 50-250 citations and includes a subject term index and title list.) (Copyright NERAC, Inc. 1995)

  4. Source mask optimization study based on latest Nikon immersion scanner

    Science.gov (United States)

    Zhu, Jun; Wei, Fang; Chen, Lijun; Zhang, Chenming; Zhang, Wei; Nishinaga, Hisashi; El-Sewefy, Omar; Gao, Gen-Sheng; Lafferty, Neal; Meiring, Jason; Zhang, Recoo; Zhu, Cynthia

    2016-03-01

    The 2x nm logic foundry node has many challenges since critical levels are pushed close to the limits of low k1 ArF water immersion lithography. For these levels, improvements in lithographic performance can translate to decreased rework and increased yield. Source Mask Optimization (SMO) is one such route to realize these image fidelity improvements. During SMO, critical layout constructs are intensively optimized in both the mask and source domain, resulting in a solution for maximum lithographic entitlement. From the hardware side, advances in source technology have enabled free-form illumination. The approach allows highly customized illumination, enabling the practical application of SMO sources. The customized illumination sources can be adjusted for maximum versatility. In this paper, we present a study on a critical layer of an advanced foundry logic node using the latest ILT based SMO software, paired with state-of-the-art scanner hardware and intelligent illuminator. Performance of the layer's existing POR source is compared with the ideal SMO result and the installed source as realized on the intelligent illuminator of an NSR-S630D scanner. Both simulation and on-silicon measurements are used to confirm that the performance of the studied layer meets established specifications.

  5. HgCdTe Detectors for Space and Science Imaging: General Issues and Latest Achievements

    Science.gov (United States)

    Gravrand, O.; Rothman, J.; Cervera, C.; Baier, N.; Lobre, C.; Zanatta, J. P.; Boulade, O.; Moreau, V.; Fieque, B.

    2016-09-01

    HgCdTe (MCT) is a very versatile material system for infrared (IR) detection, suitable for high performance detection in a wide range of applications and spectral ranges. Indeed, the ability to tailor the cutoff frequency as close as possible to the needs makes it a perfect candidate for high performance detection. Moreover, the high quality material available today, grown either by molecular beam epitaxy or liquid phase epitaxy, allows for very low dark currents at low temperatures, suitable for low flux detection applications such as science imaging. MCT has also demonstrated robustness to the aggressive environment of space and faces, therefore, a large demand for space applications. A satellite may stare at the earth, in which case detection usually involves a lot of photons, called a high flux scenario. Alternatively, a satellite may stare at outer space for science purposes, in which case the detected photon number is very low, leading to low flux scenarios. This latter case induces very strong constraints onto the detector: low dark current, low noise, (very) large focal plane arrays. The classical structure used to fulfill those requirements are usually p/ n MCT photodiodes. This type of structure has been deeply investigated in our laboratory for different spectral bands, in collaboration with the CEA Astrophysics lab. However, another alternative may also be investigated with low excess noise: MCT n/ p avalanche photodiodes (APD). This paper reviews the latest achievements obtained on this matter at DEFIR (LETI and Sofradir common laboratory) from the short wave infrared (SWIR) band detection for classical astronomical needs, to long wave infrared (LWIR) band for exoplanet transit spectroscopy, up to very long wave infrared (VLWIR) bands. The different available diode architectures ( n/ p VHg or p/ n, or even APDs) are reviewed, including different available ROIC architectures for low flux detection.

  6. Awareness of Iranian’s General Dentists Regarding the Latest Prophylaxis Guideline for Prevention of Infective Endocarditis

    Directory of Open Access Journals (Sweden)

    Ghaderi F.

    2013-03-01

    Full Text Available Statement of Problem: Dental procedures leading to oral tissue injuries may provoke bacterial release to the blood stream causing infective endocarditis (IE in vulnerable patients. The guideline which was proposed by AHA has been updated 9 times having the last update published in 2007. This study was endeavored to uncover the level of knowledge of general dental practitioners in Shiraz, concerning the 2007 AHA guidelines for endocarditis prophylaxis in patients with cardiac problems receiving dental treatments.Materials and Method: This cross- sectional and descriptive analytical study included 150 dentists as participants. All practitioners were given a self –report questionnaire which consisted of three sections. Questions were designed to assess their knowledge of antibiotic prophylaxis in patients with cardiac disease. Results: Almost all participants (93% were aware of antibiotic prophylaxis to be essential for tooth extraction. Most participants did not believe in prophylaxis for noninvasive procedures (such as shedding of primary teeth, impression, intraoral radiography. From all of the respondents, 75% considered Amoxicillin to be the anti-biotic of choice and 57% were acquainted with the correct dose of Amoxicillin for high risk patients.Conclusion: The study identified a potential for under/over prescription of antibiotic prophylaxis under the current guideline. Burden of IE necessitates more accurate knowledge of antibiotic prophylaxis in the undergraduate curriculum and continuing education programs of dentistry.

  7. Mammalian community response to the latest Paleocene thermal maximum: An isotaphonomic study in the northern Bighorn Basin, Wyoming

    Science.gov (United States)

    Clyde, William C.; Gingerich, Philip D.

    1998-11-01

    New stratigraphic and paleontological information from the McCullough Peaks, northern Bighorn Basin, Wyoming, is incorporated into an isotaphonomic faunal database and used to investigate the impact of the latest Paleocene thermal maximum and coincident earliest Wasatchian immigration event on local mammalian community structure. Surface collections from Willwood Formation overbank deposits provide taphonomically consistent and stratigraphically resolved samples of the medium- to large-sized components of underlying mammalian communities. Rarefaction shows that the immigration event caused an abrupt and dramatic increase in species richness and evenness. After this initial increase, diversity tapered off to more typical Wasatchian levels that were still higher than those in the preceding Clarkforkian. Wasatchian immigrants were rapidly incorporated into the new community organization, representing ˜20% of the taxa and ˜50% of the individuals. Immigrant taxa generally had larger body sizes and more herbivorous and frugivorous dietary habits compared to endemic taxa, causing significant turnover in body-size structure and trophic structure. There was a significant short-term body-size decrease in many lineages that may have been prompted by the elevated temperatures and/or decreased latitudinal thermal gradients during the latest Paleocene thermal maximum. Rapid short-term climatic change (transient climates) and associated biotic dispersal can have abrupt and long-lasting effects on mammalian community evolution.

  8. The Latest Fashion Trends

    Institute of Scientific and Technical Information of China (English)

    1997-01-01

    Twice each year Chinese designers reveal the latest fashion trends. Working together with mills and garment enterprises, riley turn the study and prediction of prevailing styles into the driving force for the fashion industry’s development. Different clothing manufacturers may understand and make use of such trend analysis according to the specific kinds of garments they produce, one of the important elements in today’s garment production.

  9. Quit Smoking: Latest NIH Research

    Science.gov (United States)

    ... this page please turn Javascript on. Feature: Quit Smoking Latest NIH Research Past Issues / Winter 2011 Table ... with chest X-rays. Clinical Trials Related to Smoking Clinical trials are scientific studies that try to ...

  10. Mine safety: Occupational health -- general studies. (Latest citations from the NTIS bibliographic database). Published Search

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-07-01

    The bibliography contains citations concerning occupational hazards in the metals and fossil fuel mining environment. Topics include the detection, control and effects of respirable dust, safety aspects of various mining methods, gas detection, and field surveys of specific operations. Some attention is given to legislative aspects of mine safety and benefits to the disabled.(Contains 50-250 citations and includes a subject term index and title list.) (Copyright NERAC, Inc. 1995)

  11. Latest Research: Genetic Links

    Science.gov (United States)

    ... Current Issue Past Issues Feature: Vision Latest Research: Genetic Links Past Issues / Summer 2008 Table of Contents ... inside the eye is a risk factor for glaucoma. Summer 2008 Issue: Volume 3 Number 3 Page ...

  12. Latest research related to climate change analysis with applications in impact studies over the territory of Serbia

    Science.gov (United States)

    Vukovic, Ana; Vujadinovic, Mirjam; Djurdjevic, Vladimir; Cvetkovic, Bojan; Djordjevic, Marija; Ruml, Mirjana; Rankovic-Vasic, Zorica; Przic, Zoran; Stojicic, Djurdja; Krzic, Aleksandra; Rajkovic, Borivoj

    2015-04-01

    Serbia is a country with relatively small scale terrain features with economy mostly based on local landowners' agricultural production. Climate change analysis must be downscaled accordingly, to recognize climatological features of the farmlands. Climate model simulations and impact studies significantly contribute to the future strategic planning in economic development and therefore impact analysis must be approached with high level of confidence. This paper includes research related to climate change and impacts in Serbia resulted from cooperative work of the modeling and user community. Dynamical downscaling of climate projections for the 21st century with multi-model approach and statistical bias correction are done in order to prepare model results for impact studies. Presented results are from simulations performed using regional EBU-POM model, which is forced with A1B and A2 SRES/IPCC (2007) with comparative analysis with other regional models and from the latest high resolution NMMB simulations forced with RCP8.5 IPCC scenario (2012). Application of bias correction of the model results is necessary when calculated indices are not linearly dependent on the model results and delta approach in presenting results with respect to present climate simulations is insufficient. This is most important during the summer over the north part of the country where model bias produce much higher temperatures and less precipitation, which is known as "summer drying problem" and is common in regional models' simulations over the Pannonian valley. Some of the results, which are already observed in present climate, like higher temperatures and disturbance in the precipitation pattern, lead to present and future advancement of the start of the vegetation period toward earlier dates, associated with an increased risk of the late spring frost, extended vegetation period, disturbed preparation for the rest period, increased duration and frequency of the draught periods, etc

  13. Double Chooz: Latest results

    CERN Document Server

    Crespo-Anadón, J I

    2014-01-01

    The latest results from the Double Chooz experiment on the neutrino mixing angle $\\theta_{13}$ are presented. A detector located at an average distance of 1050 m from the two reactor cores of the Chooz nuclear power plant has accumulated a live time of 467.90 days, corresponding to an exposure of 66.5 GW-ton-year (reactor power $\\times$ detector mass $\\times$ live time). A revised analysis has boosted the signal efficiency and reduced the backgrounds and systematic uncertainties compared to previous publications, paving the way for the two detector phase. The measured $\\sin^2 2\\theta_{13} = 0.090^{+0.032}_{-0.029}$ is extracted from a fit to the energy spectrum. A deviation from the prediction above a visible energy of 4 MeV is found, being consistent with an unaccounted reactor flux effect, which does not affect the $\\theta_{13}$ result. A consistent value of $\\theta_{13}$ is measured in a rate-only fit to the number of observed candidates as a function of the reactor power, confirming the robustness of the ...

  14. Air pollution tracer studies in the lower atmosphere. (Latest citations from the NTIS bibliographic database). Published Search

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-05-01

    The bibliography contains citations concerning the use of tracers to study lower atmospheric air pollution movements. Citations discuss project descriptions and results, techniques, and tracer materials. Tracer movement from nuclear power plants, industrial stacks, and urban areas is discussed. (Contains 50-250 citations and includes a subject term index and title list.) (Copyright NERAC, Inc. 1995)

  15. New Bulletin: Latest News

    CERN Multimedia

    2005-01-01

    The paper version of the CERN Bulletin will be published twice a month with effect from 18 April 2005. The electronic version will be updated weekly. This year will see many changes in the Bulletin, designed to make it more economical, more compact and more attractive. From 18 April the paper version of the Bulletin will be published twice monthly, so we shall have to stop calling it the "Weekly". The purpose of this change in publication frequency is to redistribute the resources of the Publications Section of the Communications Group so that it can produce new brochures for the general public. However, so as not to compromise on topicality and communication of information, the Official News and General Information sections, the Pension Fund and training announcements and the seminar schedule will continue to be updated weekly. If you have signed up to be informed of the updates, you will continue to receive a weekly e-mail reminding you that the electronic version of the Bulletin has been updated. Offici...

  16. Latest Developments in Probiotics

    Science.gov (United States)

    Leroy, Frédéric; Falony, Gwen; Vuyst, Luc De

    Probiotic foods are a group of health-promoting, so-called functional foods, with large commercial interest and growing market shares (Arvanitoyannis & van Houwelingen-Koukaliaroglou, 2005). In general, their health benefits are based on the presence of selected strains of lactic acid bacteria (LAB), that, when taken up in adequate amounts, confer a health benefit on the host. They are administered mostly through the consumption of fermented milks or yoghurts (Mercenier, Pavan, & Pot, 2003). In addition to their common use in the dairy industry, probiotic LAB strains may be used in other food products too, including fermented meats (Hammes & Hertel, 1998; Incze, 1998; Kröckel, 2006; Työppönen, Petäjä,& Mattila- Sandholm, 2003).

  17. Latest LHCb results

    Directory of Open Access Journals (Sweden)

    Martinelli Maurizio

    2014-01-01

    Full Text Available The LHCb experiment is one of the major research projects at the Large Hadron Collider. Its acceptance and instrumentation is optimised to perform high-precision studies of flavour physics and particle production in a unique kinematic range at unprecedented collision energies. Using large data samples accumulated in the years 2010-2012, the LHCb collaboration has conducted a series of measurements providing a sensitive test of the Standard Model and strengthening our knowledge of flavour physics, QCD and electroweak processes. The status of the experiment and some of its recent results are presented here.

  18. Computer technology forecast study for general aviation

    Science.gov (United States)

    Seacord, C. L.; Vaughn, D.

    1976-01-01

    A multi-year, multi-faceted program is underway to investigate and develop potential improvements in airframes, engines, and avionics for general aviation aircraft. The objective of this study was to assemble information that will allow the government to assess the trends in computer and computer/operator interface technology that may have application to general aviation in the 1980's and beyond. The current state of the art of computer hardware is assessed, technical developments in computer hardware are predicted, and nonaviation large volume users of computer hardware are identified.

  19. Latest results from ALICE

    CERN Document Server

    Scapparone, Eugenio

    2011-01-01

    In this paper selected results obtained by the ALICE experiment at the LHC will be presented. Data collected during the pp runs taken at sqrt(s)=0.9, 2.76 and 7 TeV and Pb-Pb runs at sqrt(s_NN)=2.76 TeV allowed interesting studies on the properties of the hadronic and nuclear matter: proton runs gave us the possibility to explore the ordinary matter at very high energy and up to very low pt, while Pb-Pb runs provided spectacular events where several thousands of particles produced in the interaction revealed how a very dense medium behaves, providing a deeper picture on the quark gluon plasma(QGP) chemical composition and dynamics.

  20. Latest Electroweak Results from CDF

    Energy Technology Data Exchange (ETDEWEB)

    Lancaster, Mark

    2010-05-01

    The latest results in electroweak physics from proton anti-proton collisions at the Fermilab Tevatron recorded by the CDF detector are presented. The results provide constraints on parton distribution functions, the mass of the Higgs boson and beyond the Standard Model physics.

  1. Laparoscopic splenectomy: the latest technical evaluation

    Institute of Scientific and Technical Information of China (English)

    Min Tan; Chao-Xu Zheng; Zhi-Mian Wu; Guo-Tai Chen; Liu-Hua Chen; Zhen-Xian Zhao

    2003-01-01

    AIM: To introduce our latest innovation on technical manipulation of laparoscopic splenectomy.METHODS: Under general anesthesia and carbon dioxide (CO2) pneumoperitoneum, 86 cases of laparoscopic splenectomy (LS) were performed. The patients were placed in three different operative positions: 7 cases in the lithotomic position, 31 cases in the right recumbent position and 48cases in the right lateral position. An ultrasonic scissors was used to dissect the pancreaticosplenic ligament, the splenocolicum ligament, lienorenal ligament and the lienophrenic ligament, respectively. Lastly, the gastrosplenic ligament and short gastric vessels were dissected. The splenic artery and vein were resected at splenic hilum with EndoGIA. The impact of different operative positions, spleen size and other events during the operation were studied.RESULTS: The laparoscopic splenectomy was successfully performed on all 86 patients from August 1997 to August 2002. No operative complications, such as peritoneal cavity infection, massive bleeding after operation and adjacent organs injured were observed. There was no death related to the operation. The study showed that different operative positions could significantly influence the manipulation of LS. The right lateral position had more advantages than the lithotomic position and the right recumbent position in LS.CONCLUSION: Most cases of LS could be accomplishedsuccessfully when patients are placed in the right lateral position. The right lateral position has more advantages than the conventional supine approach by providing a more direct view of the splenic hilum as well as other important anatomies. Regardless of operation positions, the major axis of spleen exceeding 15 cm by B-ultrasound in vitro will surely increase the difficulties of LS and therefore prolong the duration of operation. LS is a safe and feasible modality for splenectomy.

  2. General Practitioner Antimicrobial Stewardship Programme Study (GAPS)

    DEFF Research Database (Denmark)

    Avent, Minyon L; Hansen, Malene Plejdrup; Gilks, Charles;

    2016-01-01

    BACKGROUND: There is a strong link between antibiotic consumption and the rate of antibiotic resistance. In Australia, the vast majority of antibiotics are prescribed by general practitioners, and the most common indication is for acute respiratory infections. The aim of this study is to assess...... have previously been demonstrated to be effective at reducing antibiotic prescribing for acute respiratory infections, are: delayed prescribing; patient decision aids; communication training; commitment to a practice prescribing policy for antibiotics; patient information leaflet; and near patient...... testing with C-reactive protein. In addition, two sub-studies are nested in the main study: (1) point prevalence estimation carriage of bacterial upper respiratory pathogens in practice staff and asymptomatic patients; (2) feasibility of direct measures of antibiotic resistance by nose/throat swabbing...

  3. General solar energy information user study

    Energy Technology Data Exchange (ETDEWEB)

    Belew, W.W.; Wood, B.L.; Marle, T.L.; Reinhardt, C.L.

    1981-03-01

    This report describes the results of a series of telephone interviews with groups of users of information on general solar energy. These results, part of a larger study on many different solar technologies, identify types of information each group needed and the best ways to get information to each group. The report is 1 of 10 discussing study results. The overall study provides baseline data about information needs in the solar community. An earlier study identified the information user groups in the solar community and the priority (to accelerate solar energy commercialization) of getting information to each group. In the current study only high-priority groups were examined. Results from 13 groups of respondents are analyzed in this report: Loan Officers, Real Estate Appraisers, Tax Assessors, Insurers, Lawyers, Utility Representatives, Public Interest Group Representatives, Information and Agricultural Representatives, Public Interest Group Representatives, Information and Agricultural Specialists at State Cooperative Extension Service Offices, and State Energy Office Representatives. The data will be used as input to the determination of information products and services the Solar Energy Research Institute, the Solar Energy Information Data Bank Network, and the entire information outreach community should be preparing and disseminating.

  4. 新型五色草选育及应用技术研究初报%Preliminary Study on Latest Type of Five Colors Grass Flowerplot

    Institute of Scientific and Technical Information of China (English)

    贾兰虹; 张雪岩

    2012-01-01

    新型五色草花坛从景天科植物中选出,在自然低温条件下和干旱季节中试验,比老五色草抗寒抗旱,更具有应用价值。用于花坛造型显现出红、绿、黄、粉和紫粉五种色颜动态变化,不同于老五色草的静态拼色,而且,整体越冬完好。母株冬储和繁殖均在露地进行,改变了老五色草在加温温室内越冬和需要在保护地繁殖的传统方式,花坛模纹时间提前1个月,观赏期延长60d,一年建植多年享用。新型五色草可取代现行的老五色草,在寒冷地区广泛应用。%The latest type of five colors grass flowerplot was selected from the varieties of Crassulaceae.The drought resistance of latest type of five colors grass flowerplot is better than the five colors grass flowerplot in the low temperature condition and the dry season.There are better application value.It is different from the static color matching of the five colors grass flowerplot.It could be showed dynamic changes of five colors grass flowerplot which are red,green,yellow,pink and purple-pink.It could be over winter comepletely.Stock plants are stored in winter and cultivated in open field.It changes the traditional way which need heat to be over winter in the greenhouse and cultivate in protected field.The mosaic flowerplot could plant one month ahead of time compared with the five colors grass flowerplot.The ornamental period could be extended 60 days.The latest type five colors grass flowerplot could replace the five colors grass flowerplot and apply in cold area widely.

  5. Latest AMS Results on Cosmic Ray fluxes

    Science.gov (United States)

    Bertucci, Bruna; AMS Collaboration

    2017-01-01

    AMS-02 is a wide acceptance high-energy physics experiment installed on the International Space Station in May 2011 and it has been operating continuously since then. Accurate studies of CR composition and energy spectra can be performed in AMS thanks to the unprecedented collected statistics - more than 90 billion events as of today - and the redundant measurements of particle charge, velocity, rigidity and energy. In this contribution we will present an overview of the latest results on anti-particles, electrons and light nuclei fluxes. On behalf of the AMS Collaboration.

  6. Cina Benteng: The Latest Generations and Acculturation

    Directory of Open Access Journals (Sweden)

    Billy Nathan Setiawan

    2015-03-01

    Full Text Available The aim of this paper was to investigate the acculturation process encountered by the two latest generations of Cina Benteng. A Skype interview was conducted with two young Cina Benteng descents. The analysis was also supported by insightful remark from the parents of the two interviewees. This study discovers that the two generations seem to respond to the acculturation process in different ways. However, although some traditions are no longer relevant to the later generation, their identity as a Chinese descent cannot be easily removed.

  7. Study on a General Hopf Hierarchy

    Science.gov (United States)

    Cui, Min-Jie; Lou, Sen-Yue

    2016-04-01

    By using a general symmetry theory related to invariant functions, strong symmetry operators and hereditary operators, we find a general integrable hopf heirarchy with infinitely many general symmetries and Lax pairs. For the first order Hopf equation, there exist infinitely many symmetries which can be expressed by means of an arbitrary function in arbitrary dimensions. The general solution of the first order Hopf equation is obtained via hodograph transformation. For the second order Hopf equation, the Hopf-diffusion equation, there are five sets of infinitely many symmetries. Especially, there exist a set of primary branch symmetry with which contains an arbitrary solution of the usual linear diffusion equation. Some special implicit exact group invariant solutions of the Hopf-diffusion equation are also given. Supported by the National Natural Science Foundation of China Grant under Nos. 11435005, 11175092, and 11205092, Shanghai Knowledge Service Platform for Trustworthy Internet of Things under Grant No. ZF1213 and K.C. Wong Magna Fund in Ningbo University

  8. Latest design of gate valves

    Energy Technology Data Exchange (ETDEWEB)

    Kurzhofer, U.; Stolte, J.; Weyand, M.

    1996-12-01

    Babcock Sempell, one of the most important valve manufacturers in Europe, has delivered valves for the nuclear power industry since the beginning of the peaceful application of nuclear power in the 1960s. The latest innovation by Babcock Sempell is a gate valve that meets all recent technical requirements of the nuclear power technology. At the moment in the United States, Germany, Sweden, and many other countries, motor-operated gate and globe valves are judged very critically. Besides the absolute control of the so-called {open_quotes}trip failure,{close_quotes} the integrity of all valve parts submitted to operational forces must be maintained. In case of failure of the limit and torque switches, all valve designs have been tested with respect to the quality of guidance of the gate. The guidances (i.e., guides) shall avoid a tilting of the gate during the closing procedure. The gate valve newly designed by Babcock Sempell fulfills all these characteristic criteria. In addition, the valve has cobalt-free seat hardfacing, the suitability of which has been proven by friction tests as well as full-scale blowdown tests at the GAP of Siemens in Karlstein, West Germany. Babcock Sempell was to deliver more than 30 gate valves of this type for 5 Swedish nuclear power stations by autumn 1995. In the presentation, the author will report on the testing performed, qualifications, and sizing criteria which led to the new technical design.

  9. Zika virus: the latest newcomer

    Directory of Open Access Journals (Sweden)

    Juan-Carlos eSaiz

    2016-04-01

    Full Text Available Since the beginning of this century, humanity has been facing a new emerging, or re-emerging, virus threat almost every year: West Nile, Influenza A, avian flu, dengue, Chikungunya, SARS, MERS, Ebola, and now Zika, the latest newcomer. Zika virus (ZIKV, a flavivirus transmitted by Aedes mosquitoes, was identified in 1947 in a sentinel monkey in Uganda, and later on in humans in Nigeria. The virus was mainly confined to the African continent until it was detected in south-east Asia the 1980´s, then in the Micronesia in 2007 and, more recently in the Americas in 2014, where it has displayed an explosive spread, as advised by the World Health Organization (WHO, which resulted in the infection of hundreds of thousands of people. ZIKV infection was characterized by causing a mild disease presented with fever, headache, rash, arthralgia, and conjunctivitis, with exceptional reports of an association with Guillain-Barre syndrome (GBS and microcephaly. However, since the end of 2015, an increase in the number of GBS associated cases and an astonishing number of microcephaly in foetus and new-borns in Brazil have been related to ZIKV infection, raising serious worldwide public health concerns. Clarifying such worrisome relationships is, thus, a current unavoidable goal. Here, we extensively review what is currently known about ZIKV, from molecular biology, transmission routes, ecology and epidemiology, to clinical manifestations, pathogenesis, diagnosis, prophylaxis and public health.

  10. Zika Virus: the Latest Newcomer.

    Science.gov (United States)

    Saiz, Juan-Carlos; Vázquez-Calvo, Ángela; Blázquez, Ana B; Merino-Ramos, Teresa; Escribano-Romero, Estela; Martín-Acebes, Miguel A

    2016-01-01

    Since the beginning of this century, humanity has been facing a new emerging, or re-emerging, virus threat almost every year: West Nile, Influenza A, avian flu, dengue, Chikungunya, SARS, MERS, Ebola, and now Zika, the latest newcomer. Zika virus (ZIKV), a flavivirus transmitted by Aedes mosquitoes, was identified in 1947 in a sentinel monkey in Uganda, and later on in humans in Nigeria. The virus was mainly confined to the African continent until it was detected in south-east Asia the 1980's, then in the Micronesia in 2007 and, more recently in the Americas in 2014, where it has displayed an explosive spread, as advised by the World Health Organization, which resulted in the infection of hundreds of thousands of people. ZIKV infection was characterized by causing a mild disease presented with fever, headache, rash, arthralgia, and conjunctivitis, with exceptional reports of an association with Guillain-Barre syndrome (GBS) and microcephaly. However, since the end of 2015, an increase in the number of GBS associated cases and an astonishing number of microcephaly in fetus and new-borns in Brazil have been related to ZIKV infection, raising serious worldwide public health concerns. Clarifying such worrisome relationships is, thus, a current unavoidable goal. Here, we extensively review what is currently known about ZIKV, from molecular biology, transmission routes, ecology, and epidemiology, to clinical manifestations, pathogenesis, diagnosis, prophylaxis, and public health.

  11. The Latest Books on Globalization

    Directory of Open Access Journals (Sweden)

    Elia Zaru

    2016-12-01

    Full Text Available The latest books published on globalization raise interesting issues which reflect upon the very complexity of the process we are facing. In The Great Convergence: Information Technology and the New Globalization Richard Baldwin proposes a history of globalization divided into two stages. As Baldwin argues, the process of globalization has to be divided into “old” and “new” age. The “old” globalization took place between 1820 and 1990. It was characterized by the “great divergence”, that is by the centralization of world income in today’s wealthy nations. However, since 1990 the sharing of world income has plummeted to where it was in 1900. According to Baldwin, this reversal of fortune is a symptom of a shift in the globalization process. The “new” globalization, driven by information technology, has combined high tech with low wages, and lead simultaneously to the industrialization of developing nations and deindustrialization of developed ones. This is the “great convergence”: in the “new” globalization rich and developing nations are alike and they face equal global challenges.

  12. Zika Virus: the Latest Newcomer

    Science.gov (United States)

    Saiz, Juan-Carlos; Vázquez-Calvo, Ángela; Blázquez, Ana B.; Merino-Ramos, Teresa; Escribano-Romero, Estela; Martín-Acebes, Miguel A.

    2016-01-01

    Since the beginning of this century, humanity has been facing a new emerging, or re-emerging, virus threat almost every year: West Nile, Influenza A, avian flu, dengue, Chikungunya, SARS, MERS, Ebola, and now Zika, the latest newcomer. Zika virus (ZIKV), a flavivirus transmitted by Aedes mosquitoes, was identified in 1947 in a sentinel monkey in Uganda, and later on in humans in Nigeria. The virus was mainly confined to the African continent until it was detected in south-east Asia the 1980’s, then in the Micronesia in 2007 and, more recently in the Americas in 2014, where it has displayed an explosive spread, as advised by the World Health Organization, which resulted in the infection of hundreds of thousands of people. ZIKV infection was characterized by causing a mild disease presented with fever, headache, rash, arthralgia, and conjunctivitis, with exceptional reports of an association with Guillain–Barre syndrome (GBS) and microcephaly. However, since the end of 2015, an increase in the number of GBS associated cases and an astonishing number of microcephaly in fetus and new-borns in Brazil have been related to ZIKV infection, raising serious worldwide public health concerns. Clarifying such worrisome relationships is, thus, a current unavoidable goal. Here, we extensively review what is currently known about ZIKV, from molecular biology, transmission routes, ecology, and epidemiology, to clinical manifestations, pathogenesis, diagnosis, prophylaxis, and public health. PMID:27148186

  13. Study of General Incomplete Star Interconnection Networks

    Institute of Scientific and Technical Information of China (English)

    史云涛; 侯紫峰; 宋建平

    2002-01-01

    The star networks, which were originally proposed by Akers and Harel, have suffered from a rigorous restriction on the number of nodes. The general incomplete star networks (GISN) are proposed in this paper to relieve this restriction. An efficient labeling scheme for GISN is given, and routing and broadcasting algorithms are also presented for GISN. The communication diameter of GISN is shown to be bounded by 4n - 7. The proposed single node broadcasting algorithm is optimal with respect to time complexity O(n log2 n).

  14. Advanced General Aviation Turbine Engine (GATE) study

    Science.gov (United States)

    Smith, R.; Benstein, E. H.

    1979-01-01

    The small engine technology requirements suitable for general aviation service in the 1987 to 1988 time frame were defined. The market analysis showed potential United States engines sales of 31,500 per year providing that the turbine engine sales price approaches current reciprocating engine prices. An optimum engine design was prepared for four categories of fixed wing aircraft and for rotary wing applications. A common core approach was derived from the optimum engines that maximizes engine commonality over the power spectrum with a projected price competitive with reciprocating piston engines. The advanced technology features reduced engine cost, approximately 50 percent compared with current technology.

  15. Academy of General Dentistry

    Science.gov (United States)

    ... continuing education. BECOME A FELLOW OR MASTER Continuing Education Access the latest CE opportunities, including live and on-demand webinars, specifically designed for the general dentist. BROWSE ...

  16. [Latest advances of SLA class I genes].

    Science.gov (United States)

    Tao, Xuan; Li, Hua; Li, Xue-Wei; Yu, Hui; Zuo, Qi-Zhen

    2007-11-01

    The Swine leukocyte antigen (SLA) class I genes encode multi-glycoproteins on cell surface, which present endogenous antigenic peptides to T cells and thus initiate specific immune responses. In this article, latest advances on molecular structure, expression in tissues, regulation of expression, genotyping, polymorphism, and evolution of SLA class I genes were introduced, in which genotyping and polymorphism were emphasized. Molecular typing methods of SLA class I genes include serological method, DNA sequencing, PCR-SSP, PCR-SSOP and MS, of which PCR-SSP is frequently used in genotyping of SLA class I genes as a simple and rapid method. Future directions for the study and application of SLA class I genes on gene functions, peptide vaccine, xenotransplantation were also discussed.

  17. Latest results from the Pierre Auger Observatory

    Science.gov (United States)

    Dembinski, Hans P.; Pierre Auger Collaboration

    2012-02-01

    The Pierre Auger Observatory, located in the Province of Mendoza, Argentina, is the World's largest detector for cosmic rays at ultra-high energies. In its seven years of operation it has collected an exposure of more than 20000 km2 sr yr, larger than all previous experiments combined. Its original design, optimized for the energy range 1018 eV to 1020 eV, is currently enhanced to cover energies down to almost 1017 eV. We give an overview of the latest results with a focus on the prospect to study nuclear interactions with cosmic rays and conclude with a brief outlook on developments and extensions of the observatory. Full author list

  18. A Student Guide to Studying General Chemistry.

    Science.gov (United States)

    Schlenker, Richard M.

    This is a guide for introductory college chemistry students who are new to the subject of chemistry and who have been exposed to linear and second-order algebra equations and the concept of slope. The guide presents directions on the following topics: (1) How to prepare for lectures and take notes; (2) How to study chemistry outside of class using…

  19. General review of flashing jet studies.

    Science.gov (United States)

    Polanco, Geanette; Holdø, Arne Erik; Munday, George

    2010-01-15

    The major concern on the management of superheated liquids, in industrial environments, is the large potential hazards involved in cases of any accidental release. There is a possibility that a violent phase change could take place inside the fluid released generating a flashing jet. This violent phase change might produce catastrophic consequences, such as explosions, fires or toxic exposure, in the installations and in the surroundings. The knowledge and understanding of the mechanisms involved in those releases become an important issue in the prevention of these consequences and the minimization of their impact. This work presents a comprehensive review of information about flashing processes. The review begins with a description of the single phase jet followed by a description of the two-phase flashing jet. The concepts and implications of the thermodynamic and mechanical effects on the behaviour of the jets are considered at the beginning of the review. Following the review is devoted to the classification of the different study approaches used to understand flashing processes in the past, highlighting various critical parameters on the behaviour and the hazard consequences of flashing jets. The review also contains an extensive compilation of experimental, theoretical and numerical data relating to these phenomena, which includes information on the distinct characteristics of the jet, since type of jet, velocity distribution, expansion angle and mass phase change all require individual estimation.

  20. General review of flashing jet studies

    Energy Technology Data Exchange (ETDEWEB)

    Polanco, Geanette, E-mail: gpolanco@usb.ve [Simon Bolivar University, Caracas (Venezuela, Bolivarian Republic of); Holdo, Arne Erik, E-mail: Erik.Holdo@coventry.ac.uk [Narvik University College, Narvik (Norway); Munday, George, E-mail: G.Munday@isaaconsult.co.uk [Coventry University, Coventry (United Kingdom)

    2010-01-15

    The major concern on the management of superheated liquids, in industrial environments, is the large potential hazards involved in cases of any accidental release. There is a possibility that a violent phase change could take place inside the fluid released generating a flashing jet. This violent phase change might produce catastrophic consequences, such as explosions, fires or toxic exposure, in the installations and in the surroundings. The knowledge and understanding of the mechanisms involved in those releases become an important issue in the prevention of these consequences and the minimization of their impact. This work presents a comprehensive review of information about flashing processes. The review begins with a description of the single phase jet followed by a description of the two-phase flashing jet. The concepts and implications of the thermodynamic and mechanical effects on the behaviour of the jets are considered at the beginning of the review. Following the review is devoted to the classification of the different study approaches used to understand flashing processes in the past, highlighting various critical parameters on the behaviour and the hazard consequences of flashing jets. The review also contains an extensive compilation of experimental, theoretical and numerical data relating to these phenomena, which includes information on the distinct characteristics of the jet, since type of jet, velocity distribution, expansion angle and mass phase change all require individual estimation.

  1. A Generalized Deforestation and Land-Use Change Scenario Generator for Use in Climate Modelling Studies.

    Science.gov (United States)

    Tompkins, Adrian Mark; Caporaso, Luca; Biondi, Riccardo; Bell, Jean Pierre

    2015-01-01

    A new deforestation and land-use change scenario generator model (FOREST-SAGE) is presented that is designed to interface directly with dynamic vegetation models used in latest generation earth system models. The model requires a regional-scale scenario for aggregate land-use change that may be time-dependent, provided by observational studies or by regional land-use change/economic models for future projections. These land-use categories of the observations/economic model are first translated into equivalent plant function types used by the particular vegetation model, and then FOREST-SAGE disaggregates the regional-scale scenario to the local grid-scale of the earth system model using a set of risk-rules based on factors such as proximity to transport networks, distance weighted population density, forest fragmentation and presence of protected areas and logging concessions. These rules presently focus on the conversion of forest to agriculture and pasture use, but could be generalized to other land use change conversions. After introducing the model, an evaluation of its performance is shown for the land-cover changes that have occurred in the Central African Basin from 2001-2010 using retrievals from MODerate Resolution Imaging Spectroradiometer Vegetation Continuous Field data. The model is able to broadly reproduce the spatial patterns of forest cover change observed by MODIS, and the use of the local-scale risk factors enables FOREST-SAGE to improve land use change patterns considerably relative to benchmark scenarios used in the latest Coupled Model Intercomparison Project integrations. The uncertainty to the various risk factors is investigated using an ensemble of investigations, and it is shown that the model is sensitive to the population density, forest fragmentation and reforestation factors specified.

  2. A Generalized Deforestation and Land-Use Change Scenario Generator for Use in Climate Modelling Studies.

    Directory of Open Access Journals (Sweden)

    Adrian Mark Tompkins

    Full Text Available A new deforestation and land-use change scenario generator model (FOREST-SAGE is presented that is designed to interface directly with dynamic vegetation models used in latest generation earth system models. The model requires a regional-scale scenario for aggregate land-use change that may be time-dependent, provided by observational studies or by regional land-use change/economic models for future projections. These land-use categories of the observations/economic model are first translated into equivalent plant function types used by the particular vegetation model, and then FOREST-SAGE disaggregates the regional-scale scenario to the local grid-scale of the earth system model using a set of risk-rules based on factors such as proximity to transport networks, distance weighted population density, forest fragmentation and presence of protected areas and logging concessions. These rules presently focus on the conversion of forest to agriculture and pasture use, but could be generalized to other land use change conversions. After introducing the model, an evaluation of its performance is shown for the land-cover changes that have occurred in the Central African Basin from 2001-2010 using retrievals from MODerate Resolution Imaging Spectroradiometer Vegetation Continuous Field data. The model is able to broadly reproduce the spatial patterns of forest cover change observed by MODIS, and the use of the local-scale risk factors enables FOREST-SAGE to improve land use change patterns considerably relative to benchmark scenarios used in the latest Coupled Model Intercomparison Project integrations. The uncertainty to the various risk factors is investigated using an ensemble of investigations, and it is shown that the model is sensitive to the population density, forest fragmentation and reforestation factors specified.

  3. A Generalized Deforestation and Land-Use Change Scenario Generator for Use in Climate Modelling Studies

    Science.gov (United States)

    Tompkins, Adrian Mark; Caporaso, Luca; Biondi, Riccardo; Bell, Jean Pierre

    2015-01-01

    A new deforestation and land-use change scenario generator model (FOREST-SAGE) is presented that is designed to interface directly with dynamic vegetation models used in latest generation earth system models. The model requires a regional-scale scenario for aggregate land-use change that may be time-dependent, provided by observational studies or by regional land-use change/economic models for future projections. These land-use categories of the observations/economic model are first translated into equivalent plant function types used by the particular vegetation model, and then FOREST-SAGE disaggregates the regional-scale scenario to the local grid-scale of the earth system model using a set of risk-rules based on factors such as proximity to transport networks, distance weighted population density, forest fragmentation and presence of protected areas and logging concessions. These rules presently focus on the conversion of forest to agriculture and pasture use, but could be generalized to other land use change conversions. After introducing the model, an evaluation of its performance is shown for the land-cover changes that have occurred in the Central African Basin from 2001–2010 using retrievals from MODerate Resolution Imaging Spectroradiometer Vegetation Continuous Field data. The model is able to broadly reproduce the spatial patterns of forest cover change observed by MODIS, and the use of the local-scale risk factors enables FOREST-SAGE to improve land use change patterns considerably relative to benchmark scenarios used in the latest Coupled Model Intercomparison Project integrations. The uncertainty to the various risk factors is investigated using an ensemble of investigations, and it is shown that the model is sensitive to the population density, forest fragmentation and reforestation factors specified. PMID:26394392

  4. Glaucoma: Symptoms, Diagnosis, Treatment and Latest Research

    Science.gov (United States)

    ... page please turn Javascript on. Feature: Glaucoma Glaucoma: Symptoms, Diagnosis, Treatment and Latest Research Past Issues / Fall 2009 Table of Contents Symptoms and Diagnosis Glaucoma can develop in one or ...

  5. Editorial: Latest methods and advances in biotechnology.

    Science.gov (United States)

    Lee, Sang Yup; Jungbauer, Alois

    2014-01-01

    The latest "Biotech Methods and Advances" special issue of Biotechnology Journal continues the BTJ tradition of featuring the latest breakthroughs in biotechnology. The special issue is edited by our Editors-in-Chief, Prof. Sang Yup Lee and Prof. Alois Jungbauer and covers a wide array of topics in biotechnology, including the perennial favorite workhorses of the biotech industry, Chinese hamster ovary (CHO) cell and Escherichia coli. Copyright © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  6. The latest from the LHC

    CERN Multimedia

    Mathew Stracy

    As promised by the Director-General, we will start a series of regular updates detailing the status of the LHC repairs, consolidation and commissioning.As of last week all magnets in the damaged area of sector 3-4 have been removed and raised to the surface. In total 39 dipoles and 14 short straight sections are now on the surface. Four replacement magnets have been lowered and installed, and by the end of this week this figure should total seven. Cold testing replacement magnets in SM18 has resumed after the Christmas shutdown. The civil engineering work to repair the slight damage to the concrete has been completed. Outside the damaged area the Vacuum Group are cleaning some of the beam screens in situ.Both sector 1-2 and sector 5-6 are also now at room temperature and accessible. As well as routine maintenance in these sectors, one magnet from sector 1-2 which was found to have high resistance (approximately 100 nano-ohms, two orders of magnitude higher than the specified resistance) has been removed and ...

  7. Latest insights on adenovirus structure and assembly.

    Science.gov (United States)

    San Martín, Carmen

    2012-05-01

    Adenovirus (AdV) capsid organization is considerably complex, not only because of its large size (~950 Å) and triangulation number (pseudo T = 25), but also because it contains four types of minor proteins in specialized locations modulating the quasi-equivalent icosahedral interactions. Up until 2009, only its major components (hexon, penton, and fiber) had separately been described in atomic detail. Their relationships within the virion, and the location of minor coat proteins, were inferred from combining the known crystal structures with increasingly more detailed cryo-electron microscopy (cryoEM) maps. There was no structural information on assembly intermediates. Later on that year, two reports described the structural differences between the mature and immature adenoviral particle, starting to shed light on the different stages of viral assembly, and giving further insights into the roles of core and minor coat proteins during morphogenesis [1,2]. Finally, in 2010, two papers describing the atomic resolution structure of the complete virion appeared [3,4]. These reports represent a veritable tour de force for two structural biology techniques: X-ray crystallography and cryoEM, as this is the largest macromolecular complex solved at high resolution by either of them. In particular, the cryoEM analysis provided an unprecedented clear picture of the complex protein networks shaping the icosahedral shell. Here I review these latest developments in the field of AdV structural studies.

  8. Latest Insights on Adenovirus Structure and Assembly

    Directory of Open Access Journals (Sweden)

    Carmen San Martín

    2012-05-01

    Full Text Available Adenovirus (AdV capsid organization is considerably complex, not only because of its large size (~950 Å and triangulation number (pseudo T = 25, but also because it contains four types of minor proteins in specialized locations modulating the quasi-equivalent icosahedral interactions. Up until 2009, only its major components (hexon, penton, and fiber had separately been described in atomic detail. Their relationships within the virion, and the location of minor coat proteins, were inferred from combining the known crystal structures with increasingly more detailed cryo-electron microscopy (cryoEM maps. There was no structural information on assembly intermediates. Later on that year, two reports described the structural differences between the mature and immature adenoviral particle, starting to shed light on the different stages of viral assembly, and giving further insights into the roles of core and minor coat proteins during morphogenesis [1,2]. Finally, in 2010, two papers describing the atomic resolution structure of the complete virion appeared [3,4]. These reports represent a veritable tour de force for two structural biology techniques: X-ray crystallography and cryoEM, as this is the largest macromolecular complex solved at high resolution by either of them. In particular, the cryoEM analysis provided an unprecedented clear picture of the complex protein networks shaping the icosahedral shell. Here I review these latest developments in the field of AdV structural studies.

  9. Some numerical studies of the evolution of generalized parton distributions

    Energy Technology Data Exchange (ETDEWEB)

    Diehl, M.; Kugler, W.

    2007-11-15

    We study the evolution behavior of generalized parton distributions at small longitudinal momentum fraction. Particular attention is paid to the ratio of a generalized parton distribution and its forward limit, to the mixing between quarks and gluons, and to the dependence on the squared momentum transfer t. (orig.)

  10. Study on Solitary Waves of a General Boussinesq Model

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    In this paper, we employ the bifurcation method of dynamical systems to study the solitary waves and periodic waves of a generalized Boussinesq equations. All possible phase portraits in the parameter plane for the travelling wave systems are obtained. The possible solitary wave solutions, periodic wave solutions and cusp waves for the general Boussinesq type fluid model are also investigated.

  11. 关于普惠金融最新研究进展%The Latest Progress Made in the Inclusive Finance Study

    Institute of Scientific and Technical Information of China (English)

    任森春; 占韦威

    2016-01-01

    自从“普惠金融”概念提出,相关研究层出不穷。从普惠金融的内涵、指标体系的构建和影响因素三个方面梳理国内外相关文献,紧扣普惠金融最新研究进展及趋势,指出构建普惠金融指标体系是研究的焦点和难点。最后,在总结前人研究成果的基础上,对今后关于普惠金融的研究给予展望,希望对我国普惠金融的推进和发展提供一定的借鉴和参考。%Since the concept “Inclusive Finance” was put forward, people have made a lot of research about the inclusive fi-nance problem.We discussed the development trend in the inclusive finance study and focused on construction of index system from the connotation of inclusive finance, construction of index system and influencing factors analysis.On the basis of summing up the previous studies, we try to make an expectation of the future research in the Inclusive Finance.

  12. Application of AERMOD on near future air quality simulation under the latest national emission control policy of China: a case study on an industrial city.

    Science.gov (United States)

    Ma, Jieyun; Yi, Honghong; Tang, Xiaolong; Zhang, Yan; Xiang, Ying; Pu, Li

    2013-08-01

    Air quality model can be an adequate tool for future air quality prediction, also atmospheric observations supporting and emission control strategies responders. The influence of emission control policy (emission reduction targets in the national "China's 12th Five-Year Plan (2011-2015)") on the air quality in the near future over an important industrial city of China, Xuanwei in Yunnan Province, was studied by applying the AERMOD modeling system. First, our analysis demonstrated that the AERMOD modeling system could be used in the air quality simulation in the near future for SO2 and NOx under average meteorology but not for PM10. Second, after evaluating the simulation results in 2008 and 2015, ambient concentration of SO2, NOx and PM10 (only 2008) were all centered in the middle of simulation area where the emission sources concentrated, and it is probably because the air pollutions were source oriented. Last but not least, a better air quality condition will happen under the hypothesis that the average meteorological data can be used in near future simulation. However, there are still heavy polluted areas where ambient concentrations will exceed the air quality standard in near future. In spatial allocation, reduction effect of SO2 is more significant than NOx in 2015 as the contribution of SO2 from industry is more than NOx. These results inspired the regulatory applications of AERMOD modeling system in evaluating environmental pollutant control policy.

  13. Application of AERMOD on near future air quality simulation under the latest national emission control policy of China:A case study on an industrial city

    Institute of Scientific and Technical Information of China (English)

    Jieyun Ma; Honghong Yi; Xiaolong Tang; Yan Zhang; Ying Xiang; Li Pu

    2013-01-01

    Air quality model can be an adequate tool for future air quality prediction,also atmospheric observations supporting and emission control strategies responders.The influence of emission control policy (emission reduction targets in the national "China's 12th Five-Year Plan (2011-2015)") on the air quality in the near future over an important industrial city of China,Xuanwei in Yunnan Province,was studied by applying the AERMOD modeling system.First,our analysis demonstrated that the AERMOD modeling system could be used in the air quality simulation in the near future for SO2 and NOx under average meteorology but not for PM10.Second,after evaluating the simulation results in 2008 and 2015,ambient concentration of SO2,NOx and PM 10 (only 2008) were all centered in the middle of simulation area where the emission sources concentrated,and it is probably because the air pollutions were source oriented.Last but not least,a better air quality condition will happen under the hypothesis that the average meteorological data can be used in near future simulation.However,there are still heavy polluted areas where ambient concentrations will exceed the air quality standard in near future.In spatial allocation,reduction effect of SO2 is more significant than NOx in 2015 as the contribution of SO2 from industry is more than NOx.These results inspired the regulatory applications of AERMOD modeling system in evaluating environmental pollutant control policy

  14. Performance evaluation of the latest fully automated hematology analyzers in a large, commercial laboratory setting: a 4-way, side-by-side study.

    Science.gov (United States)

    Bourner, G; Dhaliwal, J; Sumner, J

    2005-01-01

    Gamma-Dynacare is a Canadian-based community laboratory partnership formed in the mid-1990s through the merger of 3 prominent Ontario medical diagnostic laboratories. Laboratory Corporation of America acquired an interest in the GD partnership in mid 2002. We service more than 10,000 community-based Canadian clinicians, hospital partners, and private clients with an integrated customer-focused system that includes specimen collection, transportation, and results reporting services. With more than 1,700 highly qualified medical, technical, and support staff and a network of laboratories, Gamma Dynacare aims to be at the forefront of technological innovation to better service the clinician base and ultimately deliver better patient care. We were looking for a hematology analyzer that would allow. (1) standardization throughout Ontario in our 4 largest sites and (2) better performance to effectively handle aged samples and minimize slide review. To select the best, most productive hematology analyzer for our environment, it was decided to perform a side-by-side comparison of the top hematology analyzers from Abbott (Cell-Dyn 3500), Beckman Coulter (LH 750), Bayer (Advia 120), and Sysmex (XE 2100), utilizing the same samples. CBC, differential and reticulocyte parameters were all evaluated according to CLSI (formerly NCCLS) and established hematology analyzer evaluation guidelines. We assessed each analyzer for precision, linearity, carryover, stability, differential capabilities, slide review rates, and throughput (clean bench studies). Two hundred samples were assessed for differential and morphology flagging on each analyzer using the reference 400 cell manual differential for comparison. Throughput was assessed by analyzing 700 consecutive samples representative of our workload mix. Stability studies at 24 hours showed that the Beckman Coulter LH 750 was least affected by EDTA, effect with minimal changes in the mean corpuscular volume (MCV) and hematocrit. Both

  15. Prevalence of anal symptoms in general practice: a prospective study.

    Science.gov (United States)

    Tournu, Géraldine; Abramowitz, Laurent; Couffignal, Camille; Juguet, Frédéric; Sénéjoux, Agnès; Berger, Stéphane; Wiart, Anne-Laure; Bernard, Marc; Provost, Françoise; Pillant-Le Moult, Hélène; Bouchard, Dominique; Aubert, Jean-Pierre

    2017-08-03

    Anal disorders are largely underestimated in general practice. Studies have shown patients conceal anal symptoms leading to late diagnosis and treatment. Management by general practitioners is poorly described. The aim of this study is to assess the prevalence of anal symptoms and their management in general practice. In this prospective, observational, national study set in France, all adult patients consulting their general practitioner during 2 days of consultation were included. Anal symptoms, whether spontaneously revealed or not, were systematically collected and assessed. For symptomatic patients, the obstacles to anal examination were evaluated. The general practitioner's diagnosis was collected and a proctologist visit was systematically proposed in case of anal symptoms. If the proctologist was consulted, his or her diagnosis was collected. From October 2014 to April 2015, 1061 patients were included by 57 general practitioners. The prevalence of anal symptoms was 15.6% (95% CI: 14-18). However, 85% of these patients did not spontaneously share their symptoms with their doctors, despite a discomfort rating of 3 out of 10 (range 1-5). Although 65% of patients agreed to an anal examination, it was not proposed in 45% of cases with anal symptoms. Performing the examination was associated with a significantly higher diagnosis rate of 76% versus 20% (p anal symptoms are significant in general practice despite the impact on quality of life. Anal examination is seldom done. Improved training of general practitioners is required to break the taboo.

  16. Agro. no 1 June Latest

    African Journals Online (AJOL)

    The combined effects of biochar (20t Cha )and NPK inorganic fertilizer. -1 ... each gave the best result in producing healthy Moringa seedlings in this study. Keyword: Biochar .... Duncan's Multiple Range Test was used for means separation ... fertilizer. This is likely to be the case as the application rates of saw dust biochar.

  17. Latest results from KLOE-2

    Directory of Open Access Journals (Sweden)

    Bloise Caterina

    2014-01-01

    Full Text Available The KLOE experiment at the Frascati φ–factory recently obtained results on i CPT and Lorentz invariance tests from the study of quantum interference of the neutral kaon pairs; ii precision measurement of the branching fraction, BR(K+ → π+π−π+(γ = 0.05565 ± 0.00031stat ± 0.00025syst, and iii on dark photon searches with the analysis of the e+e− → µµγ final state. We have also studied the transition form factors of the φ meson to the pseudoscalars, π0 and η, that is presented in a separate contribution to this volume.

  18. Comparative Study of Algorithms for Automated Generalization of Linear Objects

    Science.gov (United States)

    Azimjon, S.; Gupta, P. K.; Sukhmani, R. S. G. S.

    2014-11-01

    Automated generalization, rooted from conventional cartography, has become an increasing concern in both geographic information system (GIS) and mapping fields. All geographic phenomenon and the processes are bound to the scale, as it is impossible for human being to observe the Earth and the processes in it without decreasing its scale. To get optimal results, cartographers and map-making agencies develop set of rules and constraints, however these rules are under consideration and topic for many researches up until recent days. Reducing map generating time and giving objectivity is possible by developing automated map generalization algorithms (McMaster and Shea, 1988). Modification of the scale traditionally is a manual process, which requires knowledge of the expert cartographer, and it depends on the experience of the user, which makes the process very subjective as every user may generate different map with same requirements. However, automating generalization based on the cartographic rules and constrains can give consistent result. Also, developing automated system for map generation is the demand of this rapid changing world. The research that we have conveyed considers only generalization of the roads, as it is one of the indispensable parts of a map. Dehradun city, Uttarakhand state of India was selected as a study area. The study carried out comparative study of the generalization software sets, operations and algorithms available currently, also considers advantages and drawbacks of the existing software used worldwide. Research concludes with the development of road network generalization tool and with the final generalized road map of the study area, which explores the use of open source python programming language and attempts to compare different road network generalization algorithms. Thus, the paper discusses the alternative solutions for automated generalization of linear objects using GIS-technologies. Research made on automated of road network

  19. A qualitative study of collaboration in general practice: understanding the general practice nurse's role.

    Science.gov (United States)

    McInnes, Susan; Peters, Kath; Bonney, Andrew; Halcomb, Elizabeth

    2017-07-01

    To explore the nature of collaboration between registered nurses and general practitioners in Australian general practice. There is international recognition that collaboration between health professionals can improve care coordination, enhance health outcomes, optimise the work environment and reduce healthcare costs. However, effective collaboration requires a clear understanding of each team member's role. A qualitative approach guided by Naturalistic Inquiry was used to elicit and interpret participant narratives. Eight general practitioners and fourteen registered nurses working in general practice were purposefully recruited. Data were collected via individual, semi-structured face-to-face interviews during February to May 2015. Interviews were audio recorded and transcribed verbatim. Data were analysed using thematic analysis. Data revealed three overarching themes. This study presents the data for the overarching theme 'Understanding the general practice registered nurse's role'. Many general practitioner participants lacked clarity around the role and scope of practice of the registered nurse. At the same time, nursing participants often articulated their role as an assistant rather than as an independent health professional. This limited collaboration and the nurses' role within the team. Collaboration was enhanced when general practitioners actively sought an understanding of the registered nurses scope of practice. Clarifying the nurses' role promotes collaboration and supports nurses to work to the full extent of their practice. This is important in terms of optimising the nurses' role within the team and reinforcing their professional identity. Identification of key issues around understanding the nurses' role may help inform strategies that improve collaboration and workplace relations. © 2016 John Wiley & Sons Ltd.

  20. The Latest from the LHC

    CERN Multimedia

    In SM18 six magnets have been cold tested with good results. It has also been a good week for cyostating with five more magnets completed. In sector 3-4 interconnection work and welding has started in the area damaged on 19 September last year. Interconnection work is also ongoing on the replacement magnet for the faulty dipole removed from sector 1-2. Three separate teams are now working in the three sectors to install the new DN200 pressure release nozzles. In total 27 magnets have been completed so far, with 34 nozzles welded. A new study is also underway to include a similar pressure release system for both the stand-alone magnets (SAMs) and the triplet magnets. All about Chamonix At the public session of the LHCC (the LHC experiments committee) held Wednesday, 18 February Steve Myers, Director for Accelerators and Technology, reviewed the discussions on the LHC at the Chamonix workshop. He explained the scenarios being studied to implement the machine consolidation measures and resume operation. The ...

  1. [Latest advances in chronic pancreatitis].

    Science.gov (United States)

    Domínguez-Muñoz, J Enrique

    2013-10-01

    This article summarizes some of the recent and clinically relevant advances in chronic pancreatitis. These advances mainly concern knowledge of the etiopathogenesis of the disease, the pharmacological treatment of pain, and knowledge of the natural history of autoimmune pancreatitis. New evidence supports the relatively low prevalence of chronic alcoholic pancreatitis, and the role of tobacco in triggering the etiopathogenic mechanisms of chronic pancreatitis is better understood. Some studies have identified certain factors that are associated with having a positive genetic test in adults with chronic idiopathic pancreatitis, which should help to select those patients who should undergo genetic studies. Antioxidant therapy has been shown to be effective in reducing pain secondary to chronic pancreatitis, although the type and optimal dose of antioxidants remains to be elucidated. Finally, the development of exocrine and endocrine pancreatic insufficiency is a very common finding during the long-term follow-up of patients with autoimmune pancreatitis. Smoking also seems to play a role in this type of pancreatitis. Copyright © 2013 Elsevier España, S.L. All rights reserved.

  2. Latest aspects of mechanical filtration

    Directory of Open Access Journals (Sweden)

    Stanislav Koláček

    2013-01-01

    Full Text Available The aim of this study was to describe and unify all knowledge about mechanic filtration. The first part deals with the parameters and properties of filtration. Here some important basic concepts are explained such as pressure gradient, filter life, etc. There’s also a description of convenient filtration technology for coarse and fine materials, such as sand, smoke or soot. The second part primarily focuses on the real use and application of filters for liquid and gaseous media. The differences in construction between different types of filters for filtration of fuels, oils, hydraulic fluids, air and cabin filters are described. The last section is focused mainly on new materials for the production of filters. These materials are ceramic or nanomaterials, which can actually be enriched for example with antibacterial silver or some fungicides.

  3. [Latest advances in acute pancreatitis].

    Science.gov (United States)

    de-Madaria, Enrique

    2015-09-01

    The present article analyses the main presentations on acute pancreatitis at Digestive Disease Week 2015. Arterial pseudoaneurysm is an uncommon complication of acute pancreatitis (incidence 0.7%) and mortality from this cause is currently anecdotal. Diabetes mellitus has little impact on the clinical course of acute pancreatitis, unlike cirrhosis, which doubles the risk of mortality. Intake of unsaturated fat could be associated with an increased severity of acute pancreatitis and is a confounding factor in studies evaluating the relationship between obesity and morbidity and mortality. PET-CT (positron emission tomography-computed tomography) could be a non-invasive tool to detect infection of collections in acute pancreatitis. Peripancreatic fat necrosis is less frequent than pancreatic fat necrosis and is associated with a better clinical course. If the clinical course is poor, increasing the calibre of the percutaneous drains used in the treatment of infected necrosis can avoid surgery in 20% of patients. The use of low molecular-weight heparin in moderate or severe pancreatitis could be associated with a better clinical course, specifically with a lower incidence of necrosis. In acute recurrent pancreatitis, simvastatin is a promising drug for prophylaxis of new episodes of acute pancreatitis. Nutritional support through a nasogastric tube does not improve clinical course compared with oral nutrition. Copyright © 2015 Elsevier España, S.L.U. All rights reserved.

  4. VERITAS: Performance and Latest Results

    Science.gov (United States)

    Ong, Rene A.; VERITAS Collaboration

    2008-03-01

    VERITAS (Very Energetic Radiation Imaging Telescope Array System) is a major, newly-comissioned observatory for gamma-ray astronomy in the 100 GeV - 50 TeV energy band. The observatory, located on Mt. Hopkins, AZ, consists of four 12m-diameter telescopes that detect very high-energy gamma rays via the imaging atmospheric Cherenkov technique. VERITAS became fully operational in Spring 2007 and has embarked on a broad program of observations of galactic and extragalactic sources of interest, particularly pulsar nebulae, SNRs, X-ray binaries, AGN, and GRBs. In addition, VERITAS is carrying out sensitive studies of signatures for new physics, such as dark matter annihilations. This talk will outline the main characteristics and performance attributes of VERITAS and will summarize the major results from the observatory in the last six months. VERITAS is operated by a collaboration of scientists from institutions in the U.S., Canada, the U.K., and Ireland. Funding is provided by the NSF, DOE, and Smithsonian Institution in the U.S., NSERC in Canada, PPARC in the U.K. and National Science Foundation Ireland.

  5. The latest Light Robotics breakthroughs - Postdeadline

    DEFF Research Database (Denmark)

    Glückstad, Jesper; Palima, Darwin; Bañas, Andrew

    Contemporary nanoscopy provides functionalities, not only for observing life science on the smallest scales but also for actively reaching into and manipulating at subcellular levels. This post-deadline contribution describes the latest generation of 3D-printed micro-tools for enabling light-acti......-activated robotics on sub-diffraction scales: Light Robotics....

  6. A Reliability Generalization Study of the Geriatric Depression Scale.

    Science.gov (United States)

    Kieffer, Kevin M.; Reese, Robert J.

    2002-01-01

    Conducted a reliability generalization study of the Geriatric Depression Scale (T. Brink and others, 1982). Results from this investigation of 338 studies shows that the average score reliability across studies was 0.8482 and identifies the most important predictors of score reliability. (SLD)

  7. Latest news on SUSY from the ATLAS experiment

    CERN Document Server

    CERN. Geneva

    2016-01-01

    Despite the absence of experimental evidence, weak scale supersymmetry remains one of the best motivated and studied Standard Model extensions. This talk reports the latest ATLAS results for searches for supersymmetric (SUSY) particles, obtained with 13 to 18 fb-1 of 13 TeV data. Weak and strong production in both R-Parity conserving and R-Parity violating SUSY scenarios are considered. The searches involved final states including jets, missing transverse momentum, light leptons, taus or photons.

  8. Supersymmetry searches with ATLAS: overview and latest results

    CERN Document Server

    CERN. Geneva

    2013-01-01

    Despite the absence of experimental evidence, weak scale supersymmetry remains one of the best motivated and studied Standard Model extensions. The ATLAS experiment searches for signs of supersymmetry in a large variety of signatures involving events with abnormal production of missing transverse momentum, jets, leptons, photons, third generation fermions, gauge bosons or massive long-lived particles. The talk presents the latest results obtained in these searches.

  9. "Two Cultures" Topics for General Studies Science Courses.

    Science.gov (United States)

    Larson, James H.

    1982-01-01

    Theses proposed in C. P. Snow's book "The Two Cultures," including uncommunicative scientific and literary groups, gap between rich and poor, overpopulation, and nuclear war remain viable topics. Discusses the scientific and literary cultural gap and what can be done in general studies science courses to ameliorate the condition. (Author/JN)

  10. "Two Cultures" Topics for General Studies Science Courses.

    Science.gov (United States)

    Larson, James H.

    1982-01-01

    Theses proposed in C. P. Snow's book "The Two Cultures," including uncommunicative scientific and literary groups, gap between rich and poor, overpopulation, and nuclear war remain viable topics. Discusses the scientific and literary cultural gap and what can be done in general studies science courses to ameliorate the condition.…

  11. "Two Cultures" Topics for General Studies Science Courses.

    Science.gov (United States)

    Larson, James H.

    1982-01-01

    Theses proposed in C. P. Snow's book "The Two Cultures," including uncommunicative scientific and literary groups, gap between rich and poor, overpopulation, and nuclear war remain viable topics. Discusses the scientific and literary cultural gap and what can be done in general studies science courses to ameliorate the condition.…

  12. The Latest Development of the Theoretical Studies on Foreign Brand Management and Its Review%国外品牌管理理论研究的最新进展及其述评

    Institute of Scientific and Technical Information of China (English)

    靳代平; 董舒

    2016-01-01

    品牌管理是营销学领域研究重要内容之一。近七年国外品牌管理理论研究的最新进展表现在以下几个方面:一是对品牌管理理论纵向发展的相关问题进行了探讨,集中体现在对在线品牌社群、品牌至爱和品牌拟人化的研究;二是探讨了品牌管理理论的横向发展,集中体现在对品牌联盟、品牌与市场营销策略的研究;三是把对品牌管理理论的研究拓展到了新的领域,主要体现在对个人品牌的研究上。%Brand management is one of the main contents in marketing research field.From the latest development of the theoretic studies on foreign brand management in the recent five years, people can find the following: first, there are discussions about the longitudinal development of the brand management theories, which mainly focus on online brand community, brand favorite and brand anthropomorphism; second, there are lateral discussions about the brand management theories, which concentrate on brand alliance, brand and marketing strategy; third, there are new do-mains of brand management theories,——— mainly on personal brand management.

  13. Learning and generalization under ambiguity: an fMRI study.

    Directory of Open Access Journals (Sweden)

    J R Chumbley

    2012-01-01

    Full Text Available Adaptive behavior often exploits generalizations from past experience by applying them judiciously in new situations. This requires a means of quantifying the relative importance of prior experience and current information, so they can be balanced optimally. In this study, we ask whether the brain generalizes in an optimal way. Specifically, we used Bayesian learning theory and fMRI to test whether neuronal responses reflect context-sensitive changes in ambiguity or uncertainty about experience-dependent beliefs. We found that the hippocampus expresses clear ambiguity-dependent responses that are associated with an augmented rate of learning. These findings suggest candidate neuronal systems that may be involved in aberrations of generalization, such as over-confidence.

  14. Generalization of Rare Variant Association Tests for Longitudinal Family Studies.

    Science.gov (United States)

    Chien, Li-Chu; Hsu, Fang-Chi; Bowden, Donald W; Chiu, Yen-Feng

    2016-02-01

    Given the functional relevance of many rare variants, their identification is frequently critical for dissecting disease etiology. Functional variants are likely to be aggregated in family studies enriched with affected members, and this aggregation increases the statistical power to detect rare variants associated with a trait of interest. Longitudinal family studies provide additional information for identifying genetic and environmental factors associated with disease over time. However, methods to analyze rare variants in longitudinal family data remain fairly limited. These methods should be capable of accounting for different sources of correlations and handling large amounts of sequencing data efficiently. To identify rare variants associated with a phenotype in longitudinal family studies, we extended pedigree-based burden (BT) and kernel (KS) association tests to genetic longitudinal studies. Generalized estimating equation (GEE) approaches were used to generalize the pedigree-based BT and KS to multiple correlated phenotypes under the generalized linear model framework, adjusting for fixed effects of confounding factors. These tests accounted for complex correlations between repeated measures of the same phenotype (serial correlations) and between individuals in the same family (familial correlations). We conducted comprehensive simulation studies to compare the proposed tests with mixed-effects models and marginal models, using GEEs under various configurations. When the proposed tests were applied to data from the Diabetes Heart Study, we found exome variants of POMGNT1 and JAK1 genes were associated with type 2 diabetes.

  15. Hadron tomography studies by generalized parton distributions and distribution amplitudes

    CERN Document Server

    Kumano, S

    2016-01-01

    We discuss hadron-tomography studies for the nucleon and exotic hadrons by high-energy hadron reactions. First, the constituent-counting rule is explained for determining internal quark configurations of exotic-hadron candidates by scaling properties of high-energy exclusive cross sections. Next, possibilities are discussed for investigating the generalized parton distributions (GPDs) of the nucleon and exotic hadrons at J-PARC. In particular, we study hadronic $2 \\to 3$ process $p+p \\to N+\\pi+B$, exclusive Drell-Yan process, and exotic-hadron GPDs. For determining three-dimensional structure of unstable exotic hadrons, we consider $s$-$t$ crossed quantities of the GPDs called generalized distribution amplitudes (GDAs), which can be investigated at KEKB. We explain possible studies of the GDAs by two-photon processes.

  16. Cardiovascular morbidity in COPD: A study of the general population

    DEFF Research Database (Denmark)

    Lange, Peter; Møgelvang, Rasmus; Marott, Jacob Louis

    2010-01-01

    Although there are a number of studies on the coexistence of heart disease and COPD among patients acutely admitted to hospital, this relationship has not been accurately described in the general population. Especially data on the prevalence of both reduced lung function and impaired left...... ventricular ejection fraction (LVEF) are sparse. We used data from the 4th examination of The Copenhagen City Heart Study, which comprises 5,890 individuals with data on pulmonary and cardiac symptoms, risk factors for cardiovascular diseases, pulmonary function tests, ECG and relevant medical history. Among...... ventricular hyperthrophy was significantly more frequent among individuals with COPD (17.7%) than among participants without COPD (12.1%.), yet this relationship was no longer significant after statistical adjustment for age and gender. In the general population, subjects with COPD have a higher prevalence...

  17. Training medical students in general practice: a qualitative study among general practitioner trainers in Sri Lanka.

    Science.gov (United States)

    Ramanayake, R P J C; De Silva, A H W; Perera, D P; Sumanasekera, R D N; Athukorala, L A C L; Fernando, K A T

    2015-01-01

    Worldwide Family Medicine has gained an important place in the undergraduate medical curriculum over the last few decades and general practices have become training centers for students. Exposure to patients early in the disease process, out patient management of common problems, follow up of chronic diseases and psychosocial aspects of health and disease are educational advantages of community based training but such training could have varying impact on patients, students and trainers. This study explored the views of General Practitioner (GP) trainers on their experience in training students. This qualitative study was conducted among GP trainers of the faculty of medicine, University of Kelaniya, Sri Lanka, to explore their experience on wide range of issues related to their role as GP trainers. The interviews were recorded and transcribed verbatim. Themes expressed were identified. Altruistic reasons, self-satisfaction, self-esteem and opportunity to improve their knowledge were the motivations for their involvement in teaching. Teachers were confident of their clinical and teaching skills. They perceived that patients were willing participants of the process and benefited from it. There was a positive impact on consultation dynamics. Time pressure was the major problem and ideal number of trainees per session was two. They were willing to attend teacher training workshops to update their knowledge. GP trainers driven by altruistic reasons were willing participants of student training process. The perceived advantages of involvement of teaching for trainers and patients were an encouragement for potential trainers. University should organize training sessions for trainers which will boost their knowledge, confidence and teaching skills which will eventually benefit students.

  18. Study with lormetazepam as a hypnotic in general practice.

    Science.gov (United States)

    Pöldinger, W; Sastre-y-Hernández, M; Fichte, K

    1983-01-01

    Due to the increasing pressure to investigate new drugs under conditions met with in practice, Lormetazepam (0.5 mg) was investigated in nine general practices under the direction and collaboration of a psychiatrist used to investigations with psychopharmaceuticals. The results of a double-blind study, carried out in comparison to triazolam (0.5 mg), in a total of 94 ambulatory patients are presented.

  19. Latest oscillation results from T2K

    CERN Document Server

    Khabibullin, Marat

    2011-01-01

    The latest oscillation results obtained in the off-axis accelerator neutrino experiment T2K are presented. In the data sample, corresponding to 1.43 x 10^20 protons on target, 6 electron neutrino candidate events pass the selection criteria, while the expected number of background events for sin^2 2\\theta_{13}=0 is 1.5 \\pm 0.3 (syst.). The probability to observe six or more candidate events due to background is 0.7%, equivalent to 2.5-sigma significance. In the muon neutrino disappearance analysis the obtained atmospheric oscillation parameters are consistent with results from the Super-Kamiokande and MINOS experiments.

  20. Increase in flexibility with latest technologies

    Energy Technology Data Exchange (ETDEWEB)

    Fuebi, Michael; Krull, Florian Felix [RWE Technology GmbH, Essen (Germany); Ladwig, Michael [Alstom (Switzerland) AG, Baden (Switzerland)

    2012-07-01

    Flexibility demands on conventional power plants rise to ensure grid stability within a power generation mix with drastically increasing capacities of renewable power generation sources such as wind farms and photovoltaics. In this paper flexibility requirements for a power plant portfolio are discussed. Through selected examples of projects from RWE's current investment programme, comprising around 13 GW of efficient and flexible power plant capacity in Germany, the Netherlands, Turkey and the UK, application of the latest technologies to fulfil flexibility requirements is presented. Further, the potential of smart retrofits in terms of combined flexibility and efficiency gains is illustrated by means of an existing power plant unit retrofit project. (orig.)

  1. Latest Progress on the QUBIC Instrument

    Science.gov (United States)

    Ghribi, A.; Aumont, J.; Battistelli, E. S.; Bau, A.; Bélier, B.; Bergé, L.; Bernard, J.-Ph.; Bersanelli, M.; Bigot-Sazy, M.-A.; Bordier, G.; Bunn, E. T.; Cavaliere, F.; Chanial, P.; Coppolecchia, A.; Decourcelle, T.; De Bernardis, P.; De Petris, M.; Drilien, A.-A.; Dumoulin, L.; Falvella, M. C.; Gault, A.; Gervasi, M.; Giard, M.; Gradziel, M.; Grandsire, L.; Gayer, D.; Hamilton, J.-Ch.; Haynes, V.; Giraud-Héraud, Y.; Holtzer, N.; Kaplan, J.; Korotkov, A.; Lande, J.; Lowitz, A.; Maffei, B.; Marnieros, S.; Martino, J.; Masi, S.; Mennella, A.; Montier, L.; Murphy, A.; Ng, M. W.; Olivieri, E.; Pajot, F.; Passerini, A.; Piacentini, F.; Piat, M.; Piccirillo, L.; Pisano, G.; Prêle, D.; Rambaud, D.; Rigaut, O.; Rosset, C.; Salatino, M.; Schillaci, A.; Scully, S.; O'Sullivan, C.; Tartari, A.; Timbie, P.; Tucker, G.; Vibert, L.; Voisin, F.; Watson, B.; Zannoni, M.

    2014-09-01

    QUBIC is a unique instrument that crosses the barriers between classical imaging architectures and interferometry taking advantage from both high sensitivity and systematics mitigation. The scientific target is to detect primordial gravitational waves created by inflation by the polarization they imprint on the cosmic microwave background—the holy grail of modern cosmology. In this paper, we show the latest advances in the development of the architecture and the sub-systems of the first module of this instrument to be deployed at Dome Charlie Concordia base—Antarctica in 2015.

  2. Latest ATLAS results from Run 2

    CERN Document Server

    Gemme, Claudia; The ATLAS collaboration

    2016-01-01

    After the fi rst LHC long shutdown with upgrades to the machine and the detectors, since 2015 the ATLAS experiment recorded more than 30 fb-1 of integrated luminosity of pp collision data at 13 TeV centre- of-mass energy. The data collected to date, the detector and physics per- formance, and measurements of Standard Model processes are reviewed briefly before summarising the latest ATLAS results in the Brout- Englert-Higgs sector, where substantial progress has been made since the discovery. Searches for physics phenomena beyond the Standard Model are also summarized. These proceedings reflect only a brief summary of the material presented at the conference.

  3. Latest Progress on the QUBIC Instrument

    CERN Document Server

    Ghribi, A; Battistelli, E S; Bau, A; Bergé, L; Bernard, J-Ph; Bersanelli, M; Bigot-Sazy, M-A; Bordier, G; Bunn, E T; Cavaliere, F; Chanial, P; Coppolecchia, A; Decourcelle, T; De Bernardis, P; De Petris, M; Drilien, A-A; Dumoulin, L; Falvella, M C; Gault, A; Gervasi, M; Giard, M; Gradziel, M; Grandsire, L; Gayer, D; Hamilton, J-Ch; Haynes, V; Hiraut, Y-G; Holtzer, N; Kaplan, J; Korotkov, A; Lande, J; Lowitz, A; Maffei, B; Marnieros, S; Martino, J; Masi, S; Mennella, A; Montier, L; Murphy, A; Ng, M W; Olivieri, E; Pajot, F; Passerini, A; Piacentini, F; Piat, M; Piccirillo, L; Pisano, G; Prêle, D; Rambaud, D; Rigaut, O; Rosset, C; Salatino, M; Schillaci, A; Scully, S; O'Sullivan, C; Tartari, A; Timbie, P; Tucker, G; Vibert, L; Voisin, F; Watson, B; Zannoni, M

    2013-01-01

    QUBIC is a unique instrument that crosses the barriers between classical imaging architectures and interferometry taking advantage from both for high sensitivity and systematics mitigation. The scientific target is the detection of the primordial gravitational waves imprint on the Cosmic Microwave Background which are the proof of inflation, holy grail of modern cosmology. In this paper, we show the latest advances in the development of the architecture and the sub-systems of the first module of this instrument to be deployed in Dome Charlie Concordia base - Antarctica in 2015.

  4. Review and Latest Trends in Mobile Robots Used on Power Transmission Lines

    Directory of Open Access Journals (Sweden)

    Rogério Sales Gonçalves

    2013-12-01

    Full Text Available This paper presents the current state of the art in mobile robots used on power transmission lines. Many theoretical and experimental studies have been conducted in order to develop autonomous machines to travel along transmission lines to perform inspection and/or repair work. These machines can improve efficiency, reduce labour costs and are expected to reduce the risk of injury to maintenance personnel. Despite there already being a number of pieces of theoretical research and technological developments in this area, problems related to stability, ability and autonomy still exist. As such, first this paper presents the main studies already carried out and the devices generally used on power transmission lines. After the latest trends have been presented, a new idea for module robots carrying out inspections/maintenance of power transmission lines is presented. Finally, the future of mobile robots applied to power transmission lines is discussed.

  5. Latest climate changes in Romania :tornadoes

    Science.gov (United States)

    Pop, Elena

    2014-05-01

    Latest climate changes in Romania :tornadoes As climate change has been considered a research priority in the European Strategy for enduring development , I have done a detailed research with my students of the new climate change that has been going on in Romania for the past decade. More precisely I have studied together with my students the phenomenon of tornadoes that have seriously affected on some occasions some our our country's locations, such as Facaeni, in the county of Ialomita, in August 2002. A quite unusual phenomenon occurred on that location situated at 44.56 degrees northern latitude and at 27.89 degrees eastern longitude, that caused severe damage to the local environment and three persons lost their lives in the process, as well as other thirty people suffering from bad injuries. The magnitude of that strong phenomenon rose on the Fujita scale at level F3 which implied wing gusts between 252-300 km/ hour . A main cause of occurrence of such a severe weather was the difference in temperature of two huge air masses, one of Polar origin, and other coming from tropical latitudes . Their crossroads was on that precise territory of Romania. The duration of the worst part of the tornado path lasted only for two minutes, but the consequences of its passage were colossal : total destruction of 33 households, and other 395 were partially damaged, 1,000 people afflicted by the devastation and 100 acres of acacia tree forest ripped off the ground. The first ever recorded tornado phenomenon in Romania was around 1894-1896, considered at that time " a freak of nature" was seen as a cloud formation abnormality , an uncontrolled force of nature that had a huge impact , and at the same time, it vanished into "thin air " fast. The most affected areas in Romania by tornadoes are the south-eastern planes where the cloud formations can create fast columns of air rotating up to 500 km/hour. The local people compared the cloud funnels created on the planes to "serpents

  6. Generalizing a study of a rotating rod carrying a collar

    Energy Technology Data Exchange (ETDEWEB)

    Campos, I [Departamento de Fisica, Facultad de Ciencias, universidad Nacional Autonoma de Mexico, Apartado Postal 21-939, Mexico 04000 D.F. (Mexico); Del Valle, G; Hernandez, M G [Area de Fisica, Division de Ciencias Basicas e IngenierIa, Universidad Autonoma Metropolitana-Azcapotzalco, Apartado Postal 21-939, Mexico 04000 D.F. (Mexico); Jimenez, J L, E-mail: jlj@xanum.uam.m [Departamento de Fisica, Division de Ciencias Basicas e IngenierIa, Universidad Autonoma Metropolitana-Iztapalapa, Apartado Postal 21-939, Mexico 04000 D.F. (Mexico)

    2010-11-15

    The present work is a generalization of the work of Ribberfors and Reitz (2000 Eur. J. Phys. 21 151-7). These authors study a system consisting of a collar that is restricted to move in a path defined by a rod of some prescribed form which passes through the collar. We generalize the analysis of this system by means of canonical treatment. We show in this way that this excellent example can also be used in advanced courses on mechanics to show the power of the methods of analytical mechanics. We have that the present treatment of this example will be useful for advanced undergraduate and graduate students as well as for the teachers of these courses on classical mechanics. (letters and comments)

  7. Latest ATLAS results on $\\phi_s$

    CERN Document Server

    Reznicek, Pavel; The ATLAS collaboration

    2017-01-01

    New Physics effects beyond the predictions of the Standard Model may manifest in the $CP$-violation of $b$-hadron decays. This paper presents the latest analysis of $B^0_s \\to J/\\psi\\phi$ decay at the ATLAS experiment, measuring the $CP$-violating phase $\\phi_s$, the decay width $\\Gamma_s$ and the difference of widths between the mass eigenstates $\\Delta\\Gamma_s$. The latest results are using integrated luminosity of 14.3 fb$^{-1}$ collected by the ATLAS detector from $\\sqrt{s}$ = 8 TeV $pp$ collisions at the Large Hadron Collider, and are statistically combined with the results from 4.9 fb$^{-1}$ of $\\sqrt{s}$ = 7 TeV data, leading to: \\begin{eqnarray*} \\phi_s & = & -0.090 \\pm 0.078 \\;\\mathrm{(stat.)} \\pm 0.041 \\;\\mathrm{(syst.)~rad} ,\\;\\;\\\\ \\Delta\\Gamma_s & = & 0.085 \\pm 0.011 \\;\\mathrm{(stat.)} \\pm 0.007 \\;\\mathrm{(syst.)~ps}^{-1} ,\\;\\;\\\\ \\Gamma_s & = & 0.675 \\pm 0.003 \\;\\mathrm{(stat.)} \\pm 0.003 \\;\\mathrm{(syst.)~ps}^{-1}. \\end{eqnarray*} The results are also presented in the form...

  8. Latest results from lattice N=4 supersymmetric Yang--Mills

    CERN Document Server

    Schaich, David; Damgaard, Poul H; Giedt, Joel

    2016-01-01

    We present some of the latest results from our numerical investigations of N=4 supersymmetric Yang--Mills theory formulated on a space-time lattice. Based on a construction that exactly preserves a single supersymmetry at non-zero lattice spacing, we recently developed an improved lattice action that is now being employed in large-scale calculations. Here we update our studies of the static potential using this new action, also applying tree-level lattice perturbation theory to improve the analysis of the potential itself. Considering relatively weak couplings, we obtain results for the Coulomb coefficient that are consistent with continuum perturbation theory.

  9. Latest NIKA results and the NIKA-2 project

    CERN Document Server

    Monfardini, A; Adane, A; Ade, P; André, P; Beelen, A; Belier, B; Benoit, A; Bideaud, A; Billot, N; Bourrion, O; Calvo, M; Catalano, A; Coiffard, G; Comis, B; D'Addabbo, A; Désert, F -X; Doyle, S; Goupy, J; Kramer, C; Leclercq, S; Macias-Perez, J; Martino, J; Mauskopf, P; Mayet, F; Pajot, F; Pascale, E; Ponthieu, N; Revéret, V; Rodriguez, L; Savini, G; Schuster, K; Sievers, A; Tucker, C; Zylka, R

    2013-01-01

    NIKA (New IRAM KID Arrays) is a dual-band imaging instrument installed at the IRAM (Institut de RadioAstronomie Millimetrique) 30-meter telescope at Pico Veleta (Spain). Two distinct Kinetic Inductance Detectors (KID) focal planes allow the camera to simultaneously image a field-of-view of about 2 arc-min in the bands 125 to 175 GHz (150 GHz) and 200 to 280 GHz (240 GHz). The sensitivity and stability achieved during the last commissioning Run in June 2013 allows opening the instrument to general observers. We report here the latest results, in particular in terms of sensitivity, now comparable to the state-of-the-art Transition Edge Sensors (TES) bolometers, relative and absolute photometry. We describe briefly the next generation NIKA-2 instrument, selected by IRAM to occupy, from 2015, the continuum imager/polarimeter slot at the 30-m telescope.

  10. Latest adcances on the studies of function and evolution of bitter taste receptor gene(T2R)family%苦味受体基因家族功能和演化研究的最新进展

    Institute of Scientific and Technical Information of China (English)

    胡玲玲; 施鹏

    2009-01-01

    The perception of bitter taste, as a defensive mechanism against ingestion of toxins, plays a very vital role in animal's life because it can help animals avoid intake of poisonous substances. The ability of bitter taste detecting is extremely differential among vertebrates, which may mainly be due to their diverse living environment and dissimilar food preference. The bitter taste perception is initially mediated by the interaction between bitter tastants and their receptors. Thus, the studies of bitter taste genes (T2R) provide us an opportunity to understand the molecular basis of bitter taste perception. More recently, more and more ligands of bitter taste receptors were described in vitro functional assays. On the other hand, with the available of many vertebrate genome sequences, the study on the evolution of bitter taste receptor gene has got great progress. Studying evolutionary force can trace the change patterns of the function of bitter taste receptors in different species which can help us find more ligands of bitter taste receptors. In this review, we focus on the latest advances on the function and evolution of T2R gene family in vertebrates. Then, we propose some visions on the future studies of T2R gene family.%苦味的识别作为一种防御机制,能帮助动物避免摄入有毒物质,它在动物的长期进化过程中起着至关重要的作用.由于不同动物具有不同的生存环境和取食偏好,使苦味识别能力在动物的长期进化中产生了分化.苦味的识别源于苦味物质和苦味受体的结合,所以对编码苦味受体基因的研究成为研究苦味识别的分子基础.近年来,随着体外功能实验体系的建立,越来越多苦味受体的配体被发现.另一方面,随着许多脊椎动物基因组的测序完成,人们对苦味受体基因家族的演化研究也取得了很大的进展.对演化驱动力的研究,能够使我们了解不同物种中苦味受体功能的变

  11. Study design, participation and characteristics of The Danish General Suburban Population Study

    DEFF Research Database (Denmark)

    Bergholdt, Helle Kirstine Mørup; Bathum, Lise; Kvetny, Jan

    2013-01-01

    The aim of this article was to describe the study design, participants and baseline characteristics of The Danish General Suburban Population Study (GESUS) and to compare suburban participants with age- and gender-matched urban participants from the Copenhagen General Population Study (CGPS)....

  12. Study design, participation and characteristics of The Danish General Suburban Population Study

    DEFF Research Database (Denmark)

    Bergholdt, Helle Kirstine Mørup; Bathum, Lise; Kvetny, Jan;

    2013-01-01

    The aim of this article was to describe the study design, participants and baseline characteristics of The Danish General Suburban Population Study (GESUS) and to compare suburban participants with age- and gender-matched urban participants from the Copenhagen General Population Study (CGPS)....

  13. Study design, participation and characteristics of the Danish General Suburban Population Study

    DEFF Research Database (Denmark)

    Bergholdt, Helle Kirstine Mørup; Kvetny, Jan; Rasmussen, Dorthe;

    2013-01-01

    The aim of this article was to describe the study design, participants and baseline characteristics of The Danish General Suburban Population Study (GESUS) and to compare suburban participants with age- and gender-matched urban participants from the Copenhagen General Population Study (CGPS)....

  14. A study of the safety of tenoxicam in general practice.

    Science.gov (United States)

    Caughey, D; Waterworth, R F

    1989-11-08

    An open, noncomparative study was undertaken to examine the safety of tenoxicam, a new nonsteroidal antiinflammatory drug (NSAID) in general practice. One thousand two hundred and sixty-seven patients with rheumatic conditions were recruited by 392 general practitioners throughout New Zealand. Forty-three point six percent of patients recruited were over 65 years of age, 62.5% had some form of concomitant disease and 76.3% of patients were already receiving NSAIDs. Three hundred and four (23.9%) patients experienced adverse drug reactions, the commonest being gastrointestinal (11.4%), central and peripheral nervous system disorders (2.8%) and skin reactions (2.5%). The profile of adverse drug reactions in those more than 65 was similar to those in patients under 65 years. Of the reactions reported, 14.7% were considered severe. Three peptic ulcers were reported. There were no unexpected adverse drug reactions. Eight hundred and forty-nine patients completed 6 months treatment. Subjective assessments of overall efficacy, pain at night, pain on movement and stiffness made before treatment and at 1, 3 and 6 months posttreatment showed that tenoxicam significantly improved all parameters. The clinical response was maintained throughout the 6 month study period and was not different in patients less than or greater than 65 years.

  15. General Motors Well-to-Wheel Study - results and conclusions; General Motors Well-to-Wheel Studie - Ergebnisse und Schluesse

    Energy Technology Data Exchange (ETDEWEB)

    Wurster, R. [L-B-Systemtechnik GmbH (Germany)

    2003-07-01

    L-B Systemtechnik GmbH carried out this study on behalf of General Motors and in co-operation with BP, Exxon, Shell and Total. The study is available on the web as http://www.lbst.de/gm-wtw for downloading. This contribution presents current results, which are compared with other recent findings (e.g. the MIT study by Weiss et al. and the publication of Bossel/Elliasson). The marketing potentials of motor fuels from renewable energy sources (natural gas, Fischer-Tropsch diesel fuel, ethanol, methanol, RME, pressurised and liquid hydrogen) is compared. The contribution also presents fuel cost (Euro/a and Euro/km)for these fuels and drives. The data are derived from the LBST E2 database. [German] Die L-B-Systemtechnik GmbH (LBST) hat in 2001/2002 im Auftrag von General Motors und in Kooperation mit BP, Exxon, Shell und Total eine umfangreiche Well-to-Whell Studie fuer den technologischen Stand von 2010 durchgefuehrt. Die gesamte LBST/GM-Studie ist unter http://www.lbst.de/gm-wtw im Internet als PDF-Dokumente zum Herunterladen verfuegbar. Auf Basis dieser Untersuchung und im Vergleich zu anderen in Diskussion befindlichen neueren Arbeiten (z.B. MIT-Studie von Weiss et al., Bossel/Elliasson Papier) werden aktuelle Ergebnisse praesentiert und ableitbare Folgen fuer die Einfuehrung von Wasserstoff als Kraftstoff fuer Strassenfahrzeuge praesentiert und diskutiert. Es sollen auch die prinzipiell realisierbaren Marktpotentiale der verschiedenen verglichenenen Fahrzeugkraftstoffe (Erdgas, Fischer-Tropsch-Diesel, Ethanol, Methanol, RME, Druck- und Fluessigwasserstoff) auf Basis erneuerbarer Energiepotenziale in Europa vergleichend dargestellt werden. Nicht in der Studie untersuchte Kraftstoffkosten (Euro/MJ und Euro/km) fuer die praesentierten Kraftstoffpfade und Fahrzeugantriebe auf der Basis der LBST E2 database werden ebenfalls praesentiert. (orig.)

  16. The latest results of the ATLAS experiment

    CERN Document Server

    Samset, BH; The ATLAS collaboration

    2010-01-01

    The ATLAS experiment at the LHC has recorded proton-proton collisions at three energies. This talk reviews the early performance and physics results from ATLAS. Topics include tracking and reconstruction of resonances, electron, jet and tau reconstruction, early b-tagging, and observation of J/Psi, W and Z particles. ATLAS studies of charged particle production at 0.9 TeV and 7 TeV are shown, together with an investigation of the underlying event and an associated tuning of PYTHIA parameters. General ATLAS talk for PASCOS 2010. 20 minutes, including questions.

  17. Cardiovascular morbidity in COPD: A study of the general population

    DEFF Research Database (Denmark)

    Lange, Peter; Møgelvang, Rasmus; Marott, Jacob Louis

    2010-01-01

    ventricular ejection fraction (LVEF) are sparse. We used data from the 4th examination of The Copenhagen City Heart Study, which comprises 5,890 individuals with data on pulmonary and cardiac symptoms, risk factors for cardiovascular diseases, pulmonary function tests, ECG and relevant medical history. Among.......4% for moderate COPD (GOLD stage 2) and 2.5% for severe and very severe COPD (GOLD stages 3+4). Individuals with COPD were older and had a higher prevalence of cardiovascular risk factors and a higher prevalence of cardiovascular diseases. Among the echocardiographical findings, only the presence of left...... ventricular hyperthrophy was significantly more frequent among individuals with COPD (17.7%) than among participants without COPD (12.1%.), yet this relationship was no longer significant after statistical adjustment for age and gender. In the general population, subjects with COPD have a higher prevalence...

  18. Studies of insulin resistance in congenital generalized lipodystrophy

    DEFF Research Database (Denmark)

    Søvik, O; Vestergaard, H; Trygstad, O

    1996-01-01

    suppressed lipid oxidation in the controls. It is concluded that patients with congenital generalized lipodystrophy may present severe insulin resistance with regard to hepatic glucose production as well as muscle glycogen synthesis and lipid oxidation. The results suggest a postreceptor defect in the action......, immunoreactive protein and mRNA levels. The patients had fasting hyperinsulinaemia, and the rate of total glucose disposal was severely impaired, primarily due to a decreased non-oxidative glucose metabolism. In the patient studied with muscle biopsy, the expected activation of glycogen synthase by insulin did...... not occur. In both patients there was severely increased hepatic glucose output in the basal state, suggesting a failure of insulin to suppress hepatic gluconeogenesis. During insulin infusion a substantially elevated rate of lipid oxidation remained in the patients, in contrast to the almost completely...

  19. General Study of Perturbations in Bouncing and Cyclic Models

    Science.gov (United States)

    Mayes, Riley; Biswas, Tirthabir; Lattyak, Colleen

    2015-04-01

    Perturbations are important in both understanding and evaluating the importance of bounces and turnarounds in models that predict a cyclic evolution of our Universe. Moreover, tracking these perturbations through the entirety of the cycle is important as it provides an outlet for a qualitative comparison with Cosmic Microwave Background (CMB) observations. However, tracking these perturbations through each cycle proves difficult as the physics to describe bounces and turnarounds is not well established. Therefore, we first studied general anaytical and numerical techniques in order to understand the evolution of fluctuations in simple cosmological models where physics is better understood. In our research, we first developed analytical techniques from background solutions to establish a solid foundation for describing super-Hubble fluctuations in our early Universe. These analytical solutions were developed for both bounces and turnarounds allowing us to numerically verify and then further investigate the consequences of these solutions in models such as bounce inflation and cyclic inflation.

  20. Suppliers Showcase Their Latest Eco Collections%Suppliers Showcase Their Latest Eco Collections

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    Planet Textiles debut - conference on sustainability with internationally renowned speakers confirmed As demanct for sustainably produced fashion increases worldwide, designers and buyers attending Intertextile Shanghai Apparel Fabrics can expect to find a number of suppliers showcasing their latest eco fabric collections. In addition to a growing number of eco suppliers participating at the fair, which takes place from 18 - 21 October 2011, there will be special trend forums, designer fabrics and zones for:

  1. TECHNICAL REPORT ON STANDARDIZATION OF THE GENERAL APTITUDE TEST BATTERY, GENERAL WORKING POPULATION NORMS STUDY FOR PUERTO RICO.

    Science.gov (United States)

    Bureau of Employment Security (DOL), Washington, DC.

    THE POSSIBILITY OF PREDICTIVE ERROR WHEN APPLYING U.S. MAINLAND NORMS FOR THE GENERAL APTITUDE TEST BATTERY TO THE EMPLOYMENT COUNSELING AND SELECTION PROCESS IN PUERTO RICO, PROMPTED A STUDY TO ESTABLISH LOCAL NORMS FOR THE SPANISH LANGUAGE VERSION, BATERIA GENERAL DE PRUEBAS DE APTITUD. A STRATIFIED QUOTA SAMPLE OF 1,500 PERSONS WAS SELECTED…

  2. Extinction pattern of reef ecosystems in latest Permian

    Institute of Scientific and Technical Information of China (English)

    WU YaSheng; FAN JiaSong; JIANG HongXia; YANG Wan

    2007-01-01

    Studies of two Permian-Triassic boundary (PTB) sections on top of a Changhsingian reef in Ziyun, Guizhou Province, southwestern China indicate that the end-Permian mass extinction of reef ecosystems occurred in two steps. The first step is the extinction of all stenotropic organisms such as calcisponges and fusulinids in the latest Permian (in the Clarkina yini conodont zone). The biota after the first extinction is simple, comprising eurytropic organisms including microgastropods, ostracods, and some small burrowing organisms, or only algal mats. At the beginning of the Early Triassic (I.e. the beginning of the Hindeodus parvus zone), the environments became anoxic, and the microgastropod dominated biota or algal mats disappeared, which constituted the second episode of the mass extinction. The biota after the second extinction comprises small spherical microproblematica, some kinds of specialized organisms tolerant of anoxic or oxygen-poor conditions. As the environments became oxygenated, the specialized biota was replaced by a microgastropod-dominated simple biota. When the environmental conditions improved further, the simple biota was replaced by a diverse biota with normal-sized ammonoids, bivalves, and gastropods, representing restoration of normal oceanic conditions. Comparison with PTB sections in Dolomites, Italy and Meishan, Zhejiang Province shows that non-reef ecosystems had a similar first episode of mass extinction in the latest Permian. In the case that oceanic anoxia happened, non-reef ecosystems had a second extinction episode similar to that of reef ecosystems.

  3. Study of polytropes with Generalized polytropic Equation of State

    CERN Document Server

    Azam, M; Noreen, I; Rehman, M A

    2016-01-01

    The aim of this paper is to discuss the theory of Newtonian and relativistic polytropes with generalized polytropic equation of state. For this purpose, we formulated the general framework to discuss the physical properties of polytrops with anisotropic inner fluid distribution under conformally flat condition in the presence of charge. We investigate the stability of these polytrops in the vicinity of generalized polytropic equation through Tolman-mass. It is concluded that one of the derived models is physically acceptable.

  4. Study of polytropes with generalized polytropic equation of state

    Science.gov (United States)

    Azam, M.; Mardan, S. A.; Noureen, I.; Rehman, M. A.

    2016-06-01

    The aim of this paper is to discuss the theory of Newtonian and relativistic polytropes with a generalized polytropic equation of state. For this purpose, we formulated the general framework to discuss the physical properties of polytropes with an anisotropic inner fluid distribution under conformally flat condition in the presence of charge. We investigate the stability of these polytropes in the vicinity of a generalized polytropic equation through the Tolman mass. It is concluded that one of the derived models is physically acceptable.

  5. Studies on the Content and Policies of the Latest Adjustment of the Agricultural Production Structure%浅谈新一轮农业生产结构调整的内涵与对策

    Institute of Scientific and Technical Information of China (English)

    高淑桃; 赵晓霞; 张广博

    2001-01-01

    改革开放以来,我国的农业生产结构虽然得到了较快的调整,但与变化更快的市场相比却总是慢半拍。尤其近几年来,随着宏观经济形势的变化和农业的连年丰收,使农业生产结构面临着新的问题,迫切需要进行与以往任何一次调整不同的新一轮调整。本文拟从新一轮农业生产结构调整的社会经济背景入手,分析新一轮农业生产结构调整的内涵及其对策。%Since the reform and opening to the outside world, the agricultural production structure of our country has been adjusted at a more rapid pace. However, it still falls behind market changes. In the last few years, with the great changes of the national economy and the good harvest of the agriculture every year, the agricultural production structure is faced with new problems. Therefore, it is very urgent to carry on another new adjustment of agricultural structure which is different from the previous ones. The eassy is on the content and policies of the latest adjustment of agricultural structure by beginning with analyzing the social economic surroundings of the latest agricultural structure adjustment.

  6. Transfer RNA's latest port of call

    DEFF Research Database (Denmark)

    Santos, Manuel A S; Orellana, Omar; Ibba, Michael

    2010-01-01

    Transfer RNA, or tRNA, has the dubious honor of being a recurring historical figure in molecular biology. Much like the lead character in Woody Allen's movie Zelig, tRNA keeps on turning up in history at the right place at the right time. In this respect the timing of the 23rd installment...... of the International tRNA Workshop just a few months after the awarding of the Nobel Prize for the structure of the ribosome was particularly fitting. Over 250 scientists gathered from January 28 to February 2, 2010 in the charming town of Aveiro on the Atlantic coast of Portugal to discuss the latest advances in our...... understanding of the myriad roles of tRNA, which stretch far beyond acting as a simple adaptor in protein synthesis. Topics covered ranged from well-established areas such as the complex post-transcriptional modification of tRNAs, tRNA aminoacylation and protein synthesis, to emerging areas...

  7. Psychosurgery: review of latest concepts and applications.

    Science.gov (United States)

    Aydin, Sabri; Abuzayed, Bashar

    2013-01-01

    Although the utilization of psychosurgery has commenced in early 19th century, when compared with other neurosurgical fields, it faced many obstacles resulting in the delay of advancement of this type of surgical methodology. This was due to the insufficient knowledge of both neural networks of the brain and the pathophysiology of psychiatric diseases. The aggressive surgical treatment modalities with high mortality and morbidity rates, the controversial ethical concerns, and the introduction of antipsychotic drugs were also among those obstacles. With the recent advancements in the field of neuroscience more accurate knowledge was gained in this field offering new ideas for the management of these diseases. Also, the recent technological developments aided the surgeons to define more sophisticated and minimally invasive techniques during the surgical procedures. Maybe the most important factor in the rerising of psychosurgery is the assemblage of the experts, clinicians, and researchers in various fields of neurosciences implementing a multidisciplinary approach. In this article, the authors aim to review the latest concepts of the pathophysiology and the recent advancements of the surgical treatment of psychiatric diseases from a neurosurgical point of view. Georg Thieme Verlag KG Stuttgart · New York.

  8. Latest ATLAS measurements on top quark properties

    CERN Document Server

    Derue, Frederic; The ATLAS collaboration

    2017-01-01

    The top quark is unique among the known quarks in that it decays before it has an opportunity to form hadronic bound states. This makes measurements of its properties particularly interesting as one can access directly the properties of a bare quark. The latest measurements of these properties with the ATLAS detector at the LHC are presented using 8 TeV and 13 TeV data, excluding results from single top production. Measurements of top quark spin observables in top-antitop events, each sensitive to a different coefficient of the spin density matrix, are presented and compared to the Standard Model predictions. The helicity of the W boson from the top decays and the production angles of the top quark are further discussed. New results on the measurment of color flow effects in $t{\\bar t}$ events are presented. Limits on the rate of flavour changing neutral currents in the production or decay of the top quark are reported. The cross-section measurement of photons produced in association with top-quark pairs is a...

  9. Latest generation of halogen-containing pesticides.

    Science.gov (United States)

    Jeschke, Peter

    2017-02-01

    Agriculture is confronted with enormous challenges, from production of enough high-quality food to water use, environmental impacts and issues combined with a continually growing world population. Modern agricultural chemistry has to support farmers by providing innovative agrichemicals, used in applied agriculture. In this context, the introduction of halogen atoms into an active ingredient is still an important tool to modulate the properties of new crop protection compounds. Since 2010, around 96% of the launched products (herbicides, fungicides, insecticides/acaricides and nematicides) contain halogen atoms. The launched nematicides contain the largest number of halogen atoms, followed by insecticides/acaricides, herbicides and fungicides. In this context, fungicides and herbicides contain in most cases fluorine atoms, whereas nematicides and insecticides contain in most cases 'mixed' halogen atoms, for example chlorine and fluorine. This review gives an overview of the latest generation of halogen-containing pesticides launched over the past 6 years and describes current halogen-containing development candidates. © 2017 Society of Chemical Industry.

  10. [Deafness in adults. Study of practices in general medicine].

    Science.gov (United States)

    Leveque, P; Kossowski, M; Pons, Y

    2012-01-01

    Deafness is a sensory disability responsible for communication disorder, sometimes impairing social life. In children, the hearing is an important concern for all stakeholders in early childhood (systematic neonatal screening, etc.). On the other hand, in the adult, it is rarely tested, and patients do consult when their audiometric status is already badly impaired. But their care is all the better if the deafness diagnosis is made early, as for the audio-prosthetic rehabilitation for example. Today, the general practitioner is the first link of the diagnostic and therapeutic management chain. The objective of this study was to evaluate the diagnostic practices of practitioners in front of deafness in adults. This prospective study included 74 practitioners based in "Ile de France" interviewed using a multiple choice questionnaire (MCQ) on otoscopic and audiometric diagnostics and a Script Concordance test (SC) on clinical adult deafness situations validated by a 5 experts panel. The obtained average score was 66.35% of correct answers to the MCQ and 47.76% to the SC. In our study, the surveyed practitioners showed a good level of otoscopic and audiometric diagnosis in the MCQ. However, their answers were not concordant with those of the expert panel in the SC. They have been particularly poorly performing on issues related to functional signs and their use in a given clinical situation, often driving to establish an otoscopic misdiagnosis while their diagnostic recognition of a pathological eardrum in the MCQ was rather good. These results reflect a lack of confidence in their otoscopic diagnosis related to the lack of knowledge of the causes of deafness in adults and their symptoms.

  11. A General Approach to Study the Reliability of Complex Systems

    Directory of Open Access Journals (Sweden)

    G. M. Repici

    2003-01-01

    Full Text Available In recent years new complex systems have been developed in the automotive field to increase safety and comfort. These systems integrate hardware and software to guarantee the best results in vehicle handling and make products competitive on the market.However, the increase in technical details and the utilization and integration of these complicated systems require a high level of dynamic control system reliability. In order to improve this fundamental characteristic methods can be extracted from methods used in the aeronautical field to deal with reliability and these can be integrated into one simplified method for application in the automotive field.Firstly, as a case study, we decided to analyse VDC (the Vehicle Dynamics Control system by defining a possible approach to reliability techniques. A VDC Fault Tree Analysis represents the first step in this activity: FTA enables us to recognize the critical components in all possible working conditions of a car, including cranking, during 'key-on'-'key-off ' phases, which is particularly critical for the electrical on-board system (because of voltage reduction.By associating FA (Functional Analysis and FTA results with a good FFA (Functional Failure Analysis, it is possible to define the best architecture for the general system to achieve the aim of a high reliability structure.The paper will show some preliminary results from the application of this methodology, taken from various typical handling conditions from well established test procedures for vehicles.

  12. Clinical TVA-based studies: a general review

    Science.gov (United States)

    Habekost, Thomas

    2015-01-01

    In combination with whole report and partial report tasks, the theory of visual attention (TVA) can be used to estimate individual differences in five basic attentional parameters: the visual processing speed, the storage capacity of visual short-term memory, the perceptual threshold, the efficiency of top–down selectivity, and the spatial bias of attentional weighting. TVA-based assessment has been used in about 30 studies to investigate attentional deficits in a range of neurological and psychiatric conditions: (a) neglect and simultanagnosia, (b) reading disturbances, (c) aging and neurodegenerative diseases, and most recently (d) neurodevelopmental disorders. The article introduces TVA based assessment, discusses its methodology and psychometric properties, and reviews the progress made in each of the four research fields. The empirical results demonstrate the general usefulness of TVA-based assessment for many types of clinical neuropsychological research. The method’s most important qualities are cognitive specificity and theoretical grounding, but it is also characterized by good reliability and sensitivity to minor deficits. The review concludes by pointing to promising new areas for clinical TVA-based research. PMID:25852607

  13. Study of an advanced General Aviation Turbine Engine (GATE)

    Science.gov (United States)

    Gill, J. C.; Short, F. R.; Staton, D. V.; Zolezzi, B. A.; Curry, C. E.; Orelup, M. J.; Vaught, J. M.; Humphrey, J. M.

    1979-01-01

    The best technology program for a small, economically viable gas turbine engine applicable to the general aviation helicopter and aircraft market for 1985-1990 was studied. Turboshaft and turboprop engines in the 112 to 746 kW (150 to 1000 hp) range and turbofan engines up to 6672 N (1500 lbf) thrust were considered. A good market for new turbine engines was predicted for 1988 providing aircraft are designed to capitalize on the advantages of the turbine engine. Parametric engine families were defined in terms of design and off-design performance, mass, and cost. These were evaluated in aircraft design missions selected to represent important market segments for fixed and rotary-wing applications. Payoff parameters influenced by engine cycle and configuration changes were aircraft gross mass, acquisition cost, total cost of ownership, and cash flow. Significant advantage over a current technology, small gas turbine engines was found especially in cost of ownership and fuel economy for airframes incorporating an air-cooled high-pressure ratio engine. A power class of 373 kW (500 hp) was recommended as the next frontier for technology advance where large improvements in fuel economy and engine mass appear possible through component research and development.

  14. Clinical TVA-based studies: a general review.

    Science.gov (United States)

    Habekost, Thomas

    2015-01-01

    In combination with whole report and partial report tasks, the theory of visual attention (TVA) can be used to estimate individual differences in five basic attentional parameters: the visual processing speed, the storage capacity of visual short-term memory, the perceptual threshold, the efficiency of top-down selectivity, and the spatial bias of attentional weighting. TVA-based assessment has been used in about 30 studies to investigate attentional deficits in a range of neurological and psychiatric conditions: (a) neglect and simultanagnosia, (b) reading disturbances, (c) aging and neurodegenerative diseases, and most recently (d) neurodevelopmental disorders. The article introduces TVA based assessment, discusses its methodology and psychometric properties, and reviews the progress made in each of the four research fields. The empirical results demonstrate the general usefulness of TVA-based assessment for many types of clinical neuropsychological research. The method's most important qualities are cognitive specificity and theoretical grounding, but it is also characterized by good reliability and sensitivity to minor deficits. The review concludes by pointing to promising new areas for clinical TVA-based research.

  15. Clinical TVA-based studies: a general review

    Directory of Open Access Journals (Sweden)

    Thomas eHabekost

    2015-03-01

    Full Text Available In combination with whole report and partial report tasks, the Theory of Visual Attention (TVA can be used to estimate individual differences in five basic attentional parameters: The visual processing speed, the storage capacity of visual short-term memory, the perceptual threshold, the efficiency of top-down selectivity, and the spatial bias of attentional weighting. TVA-based assessment has been used in about 30 studies to investigate attentional deficits in a range of neurological and psychiatric conditions: (a neglect and simultanagnosia, (b reading disturbances, (c aging and neurodegenerative diseases, and most recently (d neurodevelopmental disorders. The article introduces TVA based assessment, discusses its methodology and psychometric properties, and reviews the progress made in each of the four research fields. The empirical results demonstrate the general usefulness of TVA-based assessment for many types of clinical neuropsychological research. The method’s most important qualities are cognitive specificity and theoretical grounding, but it is also characterized by good reliability and sensitivity to minor deficits. The review concludes by pointing to promising new areas for clinical TVA-based research.

  16. Latest data on metabolic diseases: Arterial Hypertension

    Directory of Open Access Journals (Sweden)

    Angelidi Angeliki

    2017-01-01

    Full Text Available Hypertension is closely related with increased cardiovascular risk and renal damage and its prevalence is even greater in elderly patients that are a highly heterogeneous group. The identification of hypertensive patients, as well as prompt initiation and timely titration of pharmacologic therapy in addition to lifestyle therapy in order to achieve blood pressure goals is of paramount importance. In general population, blood pressure goals of <140/90mmHg are recommended. However, treatment strategies and pharmacological therapy should be personalized depending on patient characteristics and comorbidities. Some drug agents or combinations should be considered as the preferential choice in specific conditions. However, the combination of two antagonists of the Renin Angiotensin System (RAS is not recommended and should be discouraged. In elderly hypertensives, it is recommended to reduce Systolic Blood Pressure (SBP between 150 and 140mmHg, provided they are in good physical and mental conditions, while a target of SBP <140mmHg may be considered, if treatment is also well tolerated. Lifestyle changes, and particularly weight loss and physical exercise, are to be recommended to all individuals with the metabolic syndrome. These interventions improve not only blood pressure, but the metabolic components of the syndrome. Antihypertensive agents that potentially improve or at least not worsen insulin sensitivity, such as RAS blockers and calcium antagonists, should be considered as the preferred drugs. Regarding patients with diabetes, lifestyle therapy and blood pressure goals of <140/90mmHg is generally recommended (American Diabetes Association, 2017. An ACE inhibitor or angiotensin receptor blocker, at the maximum tolerated dose indicated for blood pressure treatment, is the recommended first-line treatment for hypertension in patients with diabetes and albuminuria. Taking into account several studies and meta-analyses recently published

  17. Study of polytropes with generalized polytropic equation of state

    Energy Technology Data Exchange (ETDEWEB)

    Azam, M. [University of Education, Division of Science and Technology, Lahore (Pakistan); Mardan, S.A.; Noureen, I.; Rehman, M.A. [University of the Management and Technology, Department of Mathematics, Lahore (Pakistan)

    2016-06-15

    The aim of this paper is to discuss the theory of Newtonian and relativistic polytropes with a generalized polytropic equation of state. For this purpose, we formulated the general framework to discuss the physical properties of polytropes with an anisotropic inner fluid distribution under conformally flat condition in the presence of charge. We investigate the stability of these polytropes in the vicinity of a generalized polytropic equation through the Tolman mass. It is concluded that one of the derived models is physically acceptable. (orig.)

  18. Vitiligo nonsurgical treatment: a review of latest treatment researches.

    Science.gov (United States)

    Zhang, Yanfei; Mooneyan-Ramchurn, Jessini Soranambal; Zuo, Nan; Feng, Yiguo; Xiao, Shengxiang

    2014-01-01

    Vitiligo is a common depigmenting acquired disorder affecting about 1-2% of the world population, regardless of race, ethnic background, or gender. It is characterized by the appearance of milky white maculae because of a loss of melanocytes. The disfiguring nature of vitiligo causes high psychosocial morbidity. This is especially pronounced in populations with darker skin tone, likely because of the marked contrast. A variety of nonsurgical treatment regimens are currently employed in vitiligo. We reviewed the latest studies carried out on different nonsurgical treatment modalities used in vitiligo. All nonsurgical treatment aid to repigment or depigmentation the skin, however, many of them require a prolonged treatment course and may yield minimal results as well as carry unwanted side effects. There is a need for further research into the causes of vitiligo and into discovering better treatments.

  19. The latest technical solutions in rail vehicles drives

    Directory of Open Access Journals (Sweden)

    Andrzejewski Maciej

    2017-01-01

    Full Text Available The article discusses the latest trends and solutions used in the offers of rail vehicles manufacturers. The study is mainly concerned with the technical solutions used in hybrid rail vehicles, whose development has become one of the priorities for the development of rail vehicles in the European Union in recent years. Stricter emissions standards for harmful compounds in the European Union have forced manufacturers to use increasingly sophisticated technology, including hybrid drives and alternative fuels. The products and solutions offered by the major manufacturers on the market, along with their capabilities and future applications are described. The predicted trends in the development of propulsion technology for rail and road-rail vehicles are also indicated in view of the current legislative aspirations among the EU Member States.

  20. An Exploratory Review of Bangladesh Gas Sector: Latest Evidence and Areas of Further Research

    OpenAIRE

    Professor A K M A Quader; Professor Edmond Gomes

    2002-01-01

    This paper reviews and explores the latest evidence from the gas sector of Bangladesh and highlights areas that would benefit from further research. The study reported actual consumption of gas by different sectors; projection of demands by various studies and plan documents; estimates of gas reserves and potential by various studies; and operation of the International Oil Companies (IOCs) in Bangladesh.

  1. Child dental fear and general emotional problems: a pilot study

    NARCIS (Netherlands)

    Krikken, J.B.; ten Cate, J.M.; Veerkamp, J.S.J.

    2010-01-01

    AIM: This was to investigate the relation between general emotional and behavioural problems of the child and dental anxiety and dental behavioural management problems. BACKGROUND: Dental treatment involves many potentially unpleasant stimuli, which all may lead to the development of dental anxiety

  2. Respiratory Diseases in Children: studies in general practice

    NARCIS (Netherlands)

    J.H.J.M. Uijen (Hans)

    2011-01-01

    textabstractThe work presented in this thesis covers various aspects of the epidemiology, diagnosis and management of various respiratory symptoms and diseases in children frequently encountered in general practice. These respiratory tract symptoms and diseases can be categorized into symptoms and d

  3. Child dental fear and general emotional problems: a pilot study

    NARCIS (Netherlands)

    J.B. Krikken; J.M. ten Cate; J.S.J. Veerkamp

    2010-01-01

    AIM: This was to investigate the relation between general emotional and behavioural problems of the child and dental anxiety and dental behavioural management problems. BACKGROUND: Dental treatment involves many potentially unpleasant stimuli, which all may lead to the development of dental anxiety

  4. National study of parental confidence in general practitioners.

    Science.gov (United States)

    Freed, Gary L; Spike, Neil; O'Hara, Jonathan; Hiscock, Harriet; Rhodes, Anthea L

    2017-09-03

    To assess a national sample of Australian parental confidence in general practitioner (GP) care for illness and injury for their children. Cross-sectional, internet-based survey of a national, representative sample of parents of children birth - 17 years in Australia was used. Purposeful recruitment was used to achieve a national, representative sample of 2100 Australian parents, reflective of demographic and geographic distribution based on census data. Parents were asked to indicate their degree of confidence in a GP to handle medical problems as well as their preference for, and use of, paediatric speciality care for their children. Fewer than half of parents (44%) reported that they were completely confident in a GP to provide general care as defined as 'can handle almost all general health issues for my child'. A slightly greater proportion of parents (56%) were completely confident in a GP to provide care for minor injuries, defined as injuries not requiring an X-ray. Greater confidence in general care was seen among parents >40 years of age and those whose GP is always bulk billed. Parental confidence in GPs is an important issue. Our findings that fewer than half of parents are completely confident in their GP to provide general care to their child may be an influencing factor on current health-care utilisation trends. The potential implications of low parental confidence in GPs are greater numbers of emergency department presentations for children with lower urgency conditions and increased referrals of children for specialty care. © 2017 Paediatrics and Child Health Division (The Royal Australasian College of Physicians).

  5. Theory and interpretation in qualitative studies from general practice

    DEFF Research Database (Denmark)

    Malterud, Kirsti

    2016-01-01

    Objective: In this article, I want to promote theoretical awareness and commitment among qualitative researchers in general practice and suggest adequate and feasible theoretical approaches.  Approach: I discuss different theoretical aspects of qualitative research and present the basic foundations...... theory is a consistent and soundly based set of assumptions about a specific aspect of the world, predicting or explaining a phenomenon. Qualitative research is situated in an interpretative paradigm where notions about particular human experiences in context are recognized from different subject...... in qualitative analysis are presented, emphasizing substantive theories to sharpen the interpretative focus. Such approaches are clearly within reach for a general practice researcher contributing to clinical practice by doing more than summarizing what the participants talked about, without trying to become...

  6. SIMULATION STUDY OF GENERALIZED PREDICTIVE CONTROL FOR TURBINE POWER

    Institute of Scientific and Technical Information of China (English)

    Shi Xiaoping; Li Dongmei

    2004-01-01

    A GPC (generalized predictive control) law is developed to control the power of a turbine, after transforming the nonlinear mathematical model of the power regulation system into a CARIMA(controlled auto-regressive integrated moving average) form. The effect of the new control law is compared with a traditional PID (proportional, integral and differential) control law by numerical simulation. The simulation results verify the effectiveness, the correctness and the advantage of the new control scheme.

  7. Choice of Study Resources in General Chemistry by Students Who Have Little Time to Study

    Science.gov (United States)

    Bunce, Diane M.; Komperda, Regis; Dillner, Debra K.; Lin, Shirley; Schroeder, Maria J.; Hartman, JudithAnn R.

    2017-01-01

    Students with an insufficient amount of time to study are becoming more prevalent in the general college population as many who enroll in college have competing responsibilities (full-time jobs, childcare, etc.). Such students are likely to choose study resources that they consider to be both effective and efficient. Students at the U.S. Naval…

  8. Virtual reality study of paranoid thinking in the general population.

    Science.gov (United States)

    Freeman, Daniel; Pugh, Katherine; Antley, Angus; Slater, Mel; Bebbington, Paul; Gittins, Matthew; Dunn, Graham; Kuipers, Elizabeth; Fowler, David; Garety, Philippa

    2008-04-01

    Judging whether we can trust other people is central to social interaction, despite being error-prone. A fear of others can be instilled by the contemporary political and social climate. Unfounded mistrust is called paranoia, and in severe forms is a central symptom of schizophrenia. To demonstrate that individuals without severe mental illness in the general population experience unfounded paranoid thoughts, and to determine factors predictive of paranoia using the first laboratory method of capturing the experience. Two hundred members of the general public were comprehensively assessed, and then entered a virtual reality train ride populated by neutral characters. Ordinal logistic regressions (controlling for age, gender, ethnicity, education, intellectual functioning, socio-economic status, train use, playing of computer games) were used to determine predictors of paranoia. The majority agreed that the characters were neutral, or even thought they were friendly. However, a substantial minority reported paranoid concerns. Paranoia was strongly predicted by anxiety, worry, perceptual anomalies and cognitive inflexibility. This is the most unambiguous demonstration of paranoid ideation in the general public so far. Paranoia can be understood in terms of cognitive factors. The use of virtual reality should lead to rapid advances in the understanding of paranoia.

  9. ATRF Houses the Latest DNA Sequencing Technologies | Poster

    Science.gov (United States)

    By Ashley DeVine, Staff Writer By the end of October, the Advanced Technology Research Facility (ATRF) will be one of the few facilities in the world to house all of the latest DNA sequencing technologies.

  10. 'Eraser Challenge' Latest Harmful Social Media Trend for Kids

    Science.gov (United States)

    ... https://medlineplus.gov/news/fullstory_164228.html 'Eraser Challenge' Latest Harmful Social Media Trend for Kids Burns, ... player is the "winner." The so-called "eraser challenge" has been circulating for about a year -- but ...

  11. Latest Sickle Cell Research | NIH MedlinePlus the Magazine

    Science.gov (United States)

    ... this page please turn Javascript on. Special Section: Sickle Cell Disease Latest Sickle Cell Research Past Issues / Winter 2011 Table of Contents ... Complications of sickle cell trait 100 Years of Sickle Cell Research Dr. James B. Herrick Photo: National Library ...

  12. Etiological study of generalized lymphadenopathy in a tertiary care hospital

    Directory of Open Access Journals (Sweden)

    Subrata Halder

    2016-08-01

    Results: Among 116 patients of generalized lymphadenopathy 59.5% were non-malignant causes where 40.5% diagnosed as malignant causes. Among them tuberculosis consist of 39 (33.6%, NHL 18 (15.5%, reactive lymphadenopathy 16 (13.8%, CLL and HD 8 (6.9% each, ALL 7 (6%, SLE 5(4.3%, Kikuchi's disease 4 (3.4%, AML and RA 3 (2.6% each and castleman's disease, phenytoin lymphadenopathy, metastatic lung and breast carcinoma 1 (0.9% each. Cervical groups of lymph nodes were most commonly involved 86 patients (74.1% followed by axillary groups 73 patients (62.9%. Lymph nodes size 1.5cm were due to malignant and non-malignant granulomatous cases. FNAC give definite diagnosis 80.9% malignant cases where 76.8% in non-malignant cases. HPE shown definite diagnosis in 100% cases both malignant and non-malignant diseases. Conclusions: Tuberculosis is most common cause of generalized lymphadenopathy followed by lymphoma. And reactive lymphadenitis is also an important consideration. [Int J Res Med Sci 2016; 4(8.000: 3542-3548

  13. The estimation of patients' views on organizational aspects of a general dental practice by general dental practitioners: a survey study

    Directory of Open Access Journals (Sweden)

    Truin Gert-Jan

    2011-10-01

    Full Text Available Abstract Background Considering the changes in dental healthcare, such as the increasing assertiveness of patients, the introduction of new dental professionals, and regulated competition, it becomes more important that general dental practitioners (GDPs take patients' views into account. The aim of the study was to compare patients' views on organizational aspects of general dental practices with those of GDPs and with GDPs' estimation of patients' views. Methods In a survey study, patients and GDPs provided their views on organizational aspects of a general dental practice. In a second, separate survey, GDPs were invited to estimate patients' views on 22 organizational aspects of a general dental practice. Results For 4 of the 22 aspects, patients and GDPs had the same views, and GDPs estimated patients' views reasonably well: 'Dutch-speaking GDP', 'guarantee on treatment', 'treatment by the same GDP', and 'reminder of routine oral examination'. For 2 aspects ('quality assessment' and 'accessibility for disabled patients' patients and GDPs had the same standards, although the GDPs underestimated the patients' standards. Patients had higher standards than GDPs for 7 aspects and lower standards than GDPs for 8 aspects. Conclusion On most aspects GDPs and patient have different views, except for social desirable aspects. Given the increasing assertiveness of patients, it is startling the GDP's estimated only half of the patients' views correctly. The findings of the study can assist GDPs in adapting their organizational services to better meet the preferences of their patients and to improve the communication towards patients.

  14. Latest Pleistocene Deposition and Erosion on the New Jersey Shelf

    Science.gov (United States)

    Christensen, B. A.; Alexander, C.; Stackhouse, S.; Turner, R.; Nordfjord, S.; Austin, J.; Goff, J.; Gulick, S.; Fulthorpe, C.

    2007-12-01

    The New Jersey margin is an ideal location for the study of sedimentary response to glacioeustatic forcing because this passive continental edge is both wide and stable. Although the region has been intensively imaged and mapped geophysically, it is still far from being understood stratigraphically because of a lack of samples to constrain timing and paleo-depositional environment. This study examines the timing and nature of latest Pleistocene erosion and deposition on the shelf, using grab samples and core recovered using the AHC-800 (Active Heave Compensation - 800 m) drilling system. The latest Pleistocene shelf is characterized by (1) downcutting and erosion by rivers associated with subaerial exposure during glacial retreat of sea level; (2) deposition at the shelf edge during sea level fall associated with formation of an outer shelf wedge; and (3) deposition in estuarine environments as sea level rose. Foraminiferal and sediment textural analyses of cores samples ground truth previous seismic reflection-based interpretations of incision and paleochannel formation. Grab samples analyzed for foraminiferal content and grain size identify environment of deposition within three main bathymetric features: sand ridges, sand ribbons, and glacial scours. Radiometric dating (14C) further constrains the timing of intervals of erosion and deposition. We relate our results to other studies and suggest a complex, spatially variable shelf response to glacial advance and retreat. K-Ar analyses of hornblende crystals provide constraints on sediment sources. Two assemblages exist: one consistent with ages of Proterozoic age plutons in the New Jersey area, and another, younger, indicating mixing. K-Ar dates show a clear difference between and Holocene (930- 970 +/- 20 Ma) sedimentary assemblages and sediments older than 30 k.y, (850-880 Ma +/- 20-30 Ma). Holocene hornblend crystal ages are consistent with Grenvillian aged plutons common to the source region (e

  15. [The latest in paediatric resuscitation recommendations].

    Science.gov (United States)

    López-Herce, Jesús; Rodríguez, Antonio; Carrillo, Angel; de Lucas, Nieves; Calvo, Custodio; Civantos, Eva; Suárez, Eva; Pons, Sara; Manrique, Ignacio

    2017-04-01

    Cardiac arrest has a high mortality in children. To improve the performance of cardiopulmonary resuscitation, it is essential to disseminate the international recommendations and the training of health professionals and the general population in resuscitation. This article summarises the 2015 European Paediatric Cardiopulmonary Resuscitation recommendations, which are based on a review of the advances in cardiopulmonary resuscitation and consensus in the science and treatment by the International Council on Resuscitation. The Spanish Paediatric Cardiopulmonary Resuscitation recommendations, developed by the Spanish Group of Paediatric and Neonatal Resuscitation, are an adaptation of the European recommendations, and will be used for training health professionals and the general population in resuscitation. This article highlights the main changes from the previous 2010 recommendations on prevention of cardiac arrest, the diagnosis of cardiac arrest, basic life support, advanced life support and post-resuscitation care, as well as reviewing the algorithms of treatment of basic life support, obstruction of the airway and advanced life support. Copyright © 2016. Publicado por Elsevier España, S.L.U.

  16. 29 CFR 1607.5 - General standards for validity studies.

    Science.gov (United States)

    2010-07-01

    ..., such as those described in the Standards for Educational and Psychological Tests prepared by a joint... studies. A. Acceptable types of validity studies. For the purposes of satisfying these guidelines, users... they become accepted by the psychological profession. B. Criterion-related, content, and construct...

  17. General Analysis on the Significance of Stylistic and Rhetoric Studies

    Institute of Scientific and Technical Information of China (English)

    于珊珊

    2010-01-01

    Stylistics is a scientific study of style. It’s a mode of encoding and decoding language and can be associated with various fields. In this paper,we talk about the great significances of stylistic and rhetoric studies. It refers to great help in expressing and understanding languages; in combining the linguistics and literary criticism and in foreign language teaching.

  18. All-sky observations with HAWC: latest results

    Science.gov (United States)

    Arteaga-Velázquez, J. C.; HAWC Collaboration

    2015-08-01

    The High Altitude Water Cherenkov (HAWC) observatory is a ground-based air- shower detector designed to study cosmic rays and gamma rays with energies from 100 GeV up to 100 TeV. HAWC simultaneously surveys 2sr of the northern sky with a high duty cycle > 90% in search for photons from point and extended sources, diffuse emission, transient events and other astrophysical phenomena at multi-TeV scales against the background of cosmic rays. In fact, the study of this background will open also the possibility of doing cosmic ray physics in the GeV — TeV regime and even to perform solar studies at HAWC. The observatory will consist of a densely packed array of 300 water Cherenkov tanks (4.5 m tall and 7.3 m diameter with 4 photomultipliers each) distributed on a 22 000 m2 surface. Deployment started in March 2012 on a plateau situated on the Sierra Negra Volcano in the state of Puebla, Mexico, at an altitude of 4100 m. Construction is expected to be finished by the first months of 2015. In the mean time, HAWC has been taking data with a partial array and preliminary results have been already obtained. In this contribution, the results from the latest HAWC observations will be presented.

  19. A general method to study equilibrium partitioning of macromolecules

    DEFF Research Database (Denmark)

    The distribution of macromolecules between a confined microscopic solution and a macroscopic bulk solution plays an important role in understanding separation processes such as Size Exclusion Chromatography (SEC). In this study, we have developed an efficient computational algorithm for obtaining...

  20. plato and the teaching of entrepreneurship studies as general ...

    African Journals Online (AJOL)

    JONATHAN

    2016-08-22

    Aug 22, 2016 ... Mgbakoigba, Journal of African Studies. Vol.6 No.1. July 2016. 1 ... The second worry is the growing global melt down and the increasing rate of ..... Entrepreneurship and management in Nigeria: The concept, philosophy and ...

  1. A general method to study equilibrium partitioning of macromolecules

    DEFF Research Database (Denmark)

    The distribution of macromolecules between a confined microscopic solution and a macroscopic bulk solution plays an important role in understanding separation processes such as Size Exclusion Chromatography (SEC). In this study, we have developed an efficient computational algorithm for obtaining...... the equilibrium partition coefficient (pore-to-bulk concentration ratio) and the concentration profile inside the confining geometry. The algorithm involves two steps. First, certain characteristic structure properties of the studied macromolecule are obtained by sampling its configuration space, and second those...... data are used for the computation of partition coefficient and concentration profile for any confinement size. Our algorithm is versatile to the model and type of the macromolecule studied, and is capable of handling three types of confining geometries (slit, rectangular channel and rectangular box...

  2. HIGHER EDUCATION AND GENERAL STUDIES IN NIGERIA: A ...

    African Journals Online (AJOL)

    JONATHAN

    is a life-lasting practice that has interpretation in purpose, type and level. ... Education is the sum total of the culture which a society deliberately gives its younger ... there were few theoretical abstractions, the major aim was to instill a sense of social ..... Making use of case studies from within Nigeria, Africa and other parts of.

  3. Improving patient safety culture in general practice: An interview study

    NARCIS (Netherlands)

    N.J. Verbakel (Natasha J.); A.A. de Bont (Antoinette); T.J. Verheij; C. Wagner (Cordula); D.L.M. Zwart (Dorien Lyd Marieke)

    2015-01-01

    textabstractBackground When improving patient safety a positive safety culture is key. As little is known about improving patient safety culture in primary care, this study examined whether administering a culture questionnaire with or without a complementary workshop could be used as an interventio

  4. Large General Purpose Frame for Studying Force Vectors

    Science.gov (United States)

    Heid, Christy; Rampolla, Donald

    2011-01-01

    Many illustrations and problems on the vector nature of forces have weights and forces in a vertical plane. One of the common devices for studying the vector nature of forces is a horizontal "force table," in which forces are produced by weights hanging vertically and transmitted to cords in a horizontal plane. Because some students have…

  5. Trajectories of picky eating during childhood : A general population study

    NARCIS (Netherlands)

    Cano, Sebastian Cardona; Tiemeier, Henning; Van Hoeken, Daphne; Tharner, Anne; Jaddoe, Vincent W. V.; Hofman, Albert; Verhulst, Frank C.; Hoek, Hans W.

    2015-01-01

    ObjectiveThis cohort study describes the prevalence of picky eating and examines prognostic factors for picky eating trajectories during childhood. Methods4,018 participants of a population-based cohort with measurements from pregnancy onwards were included. Picky eating was assessed by maternal rep

  6. AMESCO General Study Environmental Impacts CO2-storage. Public summary

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2007-07-15

    The AMESCO study aims to supply environmental background information on CO2-storage in the Netherlands for the broad group of initiators and other stakeholders. By bringing together the information from the scientific world, companies and authorities and by analysing relevant policies it is intended to eludicate: which are the possible environmental effects of CO2-injection and storage; which are the possibilities for risk reduction or mitigation; which existing legislation is of relevance for CO2-storage in the deep surface; where are the gaps in knowledge and legislation with regard to CO2-storage. The report produced during the AMESCO study should be seen as a broad answer to the four questions mentioned above. In specific projects the report can be used as a background document during permitting procedures. This background information has to be supplemented with location specific information. The report can also be used as input for an environmental impact assessment (EIA). For practical reasons the AMESCO study was performed with the following scope limitations: (1) Focus on potential impacts and risks resulting from the storage of CO2; (2) Only consider CO2-storage in gas reservoirs; (3) Only consider onshore projects; (4) Only consider permanent storage; (5) Consider alternative options for CO2-storage in gas reservoirs; but not other forms of CO2-emission reduction. The scope is limited to depleted gas fields, from which the economically recoverable resources have already been taken.

  7. Study on the general model of hydrological frequency analysis

    Institute of Scientific and Technical Information of China (English)

    王浩; 秦大庸; 孙济良; 王建华

    2001-01-01

    On the basis of exponential Gamma distribution, this paper presents a model consisting of 11 kinds of distribution curves for the first time. The model contains several frequency curves used commonly in China and other countries, for example, Pearson type-3 distribution, Kritsky and Menkel (USSR) distribution, Logarithmic normal distribution, and so on. Through dealing with parameters, the model may be applicable to the hydrological extreme values of different climate regions, and has very strong flexibility. In this paper, a real case study using flood datum of 240 different hydrological stations in China is submitted and the calculating results are satisfactory.

  8. [Microscopic innervation and vascularization of the tongue. General study].

    Science.gov (United States)

    Fuentes, A; Sanchiz, O

    1992-01-01

    Our study deals with 23 prenatal human tongues, and a comparative study was carried out on one neonatal tongue and a few human and animal postnatal tongues. Sagittal and coronal sections were stained with various techniques. After the 7th week, the development of the nerves and their relationships with the neighboring structures can be observed. There are very few capillaries making up the superficial vascular network under the epithelium. The vessels whose walls are beginning to develop include the future red blood cells with their basophilic nuclei. During the whole process of evolution, there is a tight correlation between the collagen fibers and the neighboring structures. The innervation and vascularization--the latter with changes in the vascular walls--progressively increase. A short time before birth, the nerve fibers include their characteristic components, except for the Schmidt-Lantermann fissures. A considerable innervation advances towards the papillae, and anterior and posterior nerve networks enter the papillae, whose connective tissue includes groups of corpuscles on serial sections.

  9. Latest news from the High Altitude Water Cherenkov Observatory

    Science.gov (United States)

    González Muñoz, A.; HAWC Collaboration

    2016-07-01

    The High Altitude Water Cherenkov Observatory is an air shower detector designed to study very-high-energy gamma rays (˜ 100 GeV to ˜ 100 TeV). It is located in the Pico de Orizaba National Park, Mexico, at an elevation of 4100 m. HAWC started operations since August 2013 with 111 tanks and in April of 2015 the 300 tanks array was completed. HAWC's unique capabilities, with a field of view of ˜ 2 sr and a high duty cycle of 5%, allow it to survey 2/3 of the sky every day. These features makes HAWC an excellent instrument for searching new TeV sources and for the detection of transient events, like gamma-ray bursts. Moreover, HAWC provides almost continuous monitoring of already known sources with variable gamma-ray fluxes in most of the northern and part of the southern sky. These observations will bring new information about the acceleration processes that take place in astrophysical environments. In this contribution, some of the latest scientific results of the observatory will be presented.

  10. The FOXSI sounding rocket: Latest analysis and results

    Science.gov (United States)

    Camilo Buitrago-Casas, Juan; Glesener, Lindsay; Christe, Steven; Krucker, Sam; Ishikawa, Shin-Nosuke; Takahashi, Tadayuki; Ramsey, Brian; Han, Raymond

    2016-05-01

    Hard X-ray (HXR) observations are a linchpin for studying particle acceleration and hot thermal plasma emission in the solar corona. Current and past indirectly imaging instruments lack the sensitivity and dynamic range needed to observe faint HXR signatures, especially in the presences of brighter sources. These limitations are overcome by using HXR direct focusing optics coupled with semiconductor detectors. The Focusing Optics X-ray Solar Imager (FOXSI) sounding rocket experiment is a state of the art solar telescope that develops and applies these capabilities.The FOXSI sounding rocket has successfully flown twice, observing active regions, microflares, and areas of the quiet-Sun. Thanks to its far superior imaging dynamic range, FOXSI performs cleaner hard X-ray imaging spectroscopy than previous instruments that use indirect imaging methods like RHESSI.We present a description of the FOXSI rocket payload, paying attention to the optics and semiconductor detectors calibrations, as well as the upgrades made for the second flight. We also introduce some of the latest FOXSI data analysis, including imaging spectroscopy of microflares and active regions observed during the two flights, and the differential emission measure distribution of the nonflaring corona.

  11. Perturbative study on the analytic continuation for generalized gravitational entropy

    Science.gov (United States)

    Prudenziati, Andrea

    2015-05-01

    We study the analytic continuation used by Lewkowycz and Maldacena to prove the Ryu-Takayanagi formula for entanglement entropy, which is the holographic dual of the trace of the β -power of the Euclidean time evolution operator when β ∈R . This will be done perturbatively using a weakly time dependent Hamiltonian, corresponding to a small shift of the dual static background. The perturbation will be set to either satisfy the Lewkowycz-Maldacena proposal or a different analytic continuation, depending on its periodicity conditions. The two choices will be tested by computing the associated entropies and compared to the Ryu-Takayanagi formula. To our surprise we discover that, at first order, they both correctly reproduce the associated entanglement entropy. Furthermore in both cases we find unexpected divergent contributions that we have to discard in order to fit the minimal area computation, and an additional requirement on the β dependence on the metric.

  12. General Education Assessment at Private Historically Black Colleges and Universities: An Exploratory Study

    Science.gov (United States)

    Jones, Willis A.

    2010-01-01

    The majority of research on general education assessment in recent years has focused primarily on predominately white institutions. Very little is known about general education assessment at historically black colleges and universities (HBCUS). Using descriptive analysis, this exploratory study examines the state of general education assessment at…

  13. Volcanic Debris Flows of the Latest Paleozoic Arbasay Formation: Geomorphological Characters and Paleoenvironment Reconstruction of Northern Tian Shan, NW China

    Science.gov (United States)

    Yang, W.; Liu, D.; Guo, Z.

    2015-12-01

    Texturally well-preserved volcanic debris flows (also called lahars) are exposed in the Latest Paleozoic Arbasay Formation, Northern Tian Shan. LA-ICP-MS zircon dating of the intercalated fallout tuff sample provided an age of 314.4±3.4 Ma (MSWD=1.6), suggesting they were deposited at Latest Carboniferous. The lahars consist primarily of two lithofacies: massive, poorly lithified diamictites and stratified, moderately lithified gravelly sandstones. The diamictites can be generally divided into two subfacies, i.e., the matrix-supported and the clast-supported diamictites. Most diamictites are structureless and nongraded. They are thick in beds and contain large clasts up to 3 m in dimension. The gravelly sandstones display much finer particle size and have wedge or lenticular geometries. Large clasts are absent within them and the sorting characters are much better than the diamictites. Despite the different size grading, the matrix and the clasts of the two lithofacies appear to be homogeneous. The matrix is generally sandy mudstone. The clasts comprise rhyolites, dacites, andesites, andesitic basalts and basalts, same to the co-existing volcanic rocks, suggesting they originate from the cognate volcanics. The disorganized diamictites are supposed to deposit from a turbulent flood or pyroclastic surge. The gravelly sandstone lithofacies are interpreted as sand-rich flood flows or hyperconcentrated flood flows during the waning stage of a mass-flow event. The overall characteristics of the deposits suggest a mass-flow dominated alluvial fan environment. It's noteable that several syn- sedimentary normal faults occurred within these lahar deposits, indicating that the Southern Junggar Basin was in an extensional regime during the lahars' deposition. Structure is dominated by normal faulting, allowing the existence of relatively small, highly compartmentalized depocenters. This is also supported by geochemistry and detrital zircon studies.

  14. Latest trends and directions of development of crowdfunding

    Directory of Open Access Journals (Sweden)

    Joanna Pieniążek

    2014-09-01

    Full Text Available The article discusses the latest trends and directions of development of crowdfunding on selected examples of English-language websites.The scope of work includes topics such as aggregates of crowdfunding sites, local investing, franchise, pre-sales platforms, open source sites and leveraging the competitive advantages of e-commerce platforms which offer product crowdfunding. This article aims to discuss the latest trends and directions of crowdfunding, assess their usefulness and the chances of popularising the ideas presented. The article provides an overview of the literature on the subject and an analysis of the selected sites, comparison sites and crowdfunding search engines.

  15. Latest Results from VERITAS: Gamma 2016

    CERN Document Server

    Holder, J

    2016-01-01

    The VERITAS imaging atmospheric Cherenkov telescope array has been observing the northern TeV sky with four telescopes since summer 2007. Over 50 gamma-ray sources have been studied, including active and starburst galaxies, pulsars and their nebulae, supernova remnants and Galactic binary systems. We review here some of the most recent VERITAS results, and discuss the status and prospects for collaborative work with other gamma-ray instruments, and with multimessenger observatories.

  16. Portion Size: Latest Developments and Interventions.

    Science.gov (United States)

    Steenhuis, Ingrid; Poelman, Maartje

    2017-03-01

    The aim of this review is to provide an overview of (1) underlying mechanisms of the effect of portion size on energy intake, (2) external factors explaining the portion size effect and (3) interventions and measurements aimed at food portion size. Previous studies have shown that portion sizes have increased in recent decades. Many experimental studies have been conducted to unravel the mechanisms underlying the portion-size effect on food intake (e.g. the appropriateness mechanism, the 'unit bias' mechanism, the 'previous experience/expectation' mechanism, the 'visual cue' mechanism and the 'bite size' mechanism). In addition, external factors have been found to drive food portion selection and consumption (e.g. value for money, mindless eating, levels of awareness, estimation bias. Research on several interventions (ranging from 'providing information' to 'eliminating choice') have been conducted, but remain scarce, especially intervention studies in which portion size is a key focus in weight loss. Moreover, only three new instruments with respect to portion control behavior have been developed. There is considerable evidence for the portion-size effect on energy intake. However, the work on interventions targeting portion size and measurements for portion control behavior are limited. Moreover, from the literature it is not yet clear what type of interventions work best, for whom and in what context.

  17. Latest results from the Pierre Auger Observatory

    Directory of Open Access Journals (Sweden)

    Lhenry-Yvon Isabelle

    2016-01-01

    Full Text Available The Pierre Auger Observatory has been designed to investigate the origin and nature of Ultra High Energy Cosmic Rays (UHECR with energies from 1017 to 1020 eV. In this paper we will review some of the most recent results obtained from data of the Pierre Auger Observatory, namely the spectrum of cosmic rays, the anisotropies in arrival directions and the studies related to mass composition and to the number of muons measured at the ground. We will also discuss the implication of these results for assembling a consistent description of the composition, origin and propagation of cosmic rays.

  18. Latest results from the Pierre Auger Observatory

    Science.gov (United States)

    Lhenry-Yvon, Isabelle

    2016-07-01

    The Pierre Auger Observatory has been designed to investigate the origin and nature of Ultra High Energy Cosmic Rays (UHECR) with energies from 1017 to 1020 eV. In this paper we will review some of the most recent results obtained from data of the Pierre Auger Observatory, namely the spectrum of cosmic rays, the anisotropies in arrival directions and the studies related to mass composition and to the number of muons measured at the ground. We will also discuss the implication of these results for assembling a consistent description of the composition, origin and propagation of cosmic rays.

  19. Latest results of the Tunka Radio Extension

    Directory of Open Access Journals (Sweden)

    Kostunin D.

    2017-01-01

    Full Text Available The Tunka Radio Extension (Tunka-Rex is an antenna array consisting of 63 antennas at the location of the TAIGA facility (Tunka Advanced Instrument for cosmic ray physics and Gamma Astronomy in Eastern Siberia, nearby Lake Baikal. Tunka-Rex is triggered by the air-Cherenkov array Tunka-133 during clear and moonless winter nights and by the scintillator array Tunka-Grande during the remaining time. Tunka-Rex measures the radio emission from the same air-showers as Tunka-133 and Tunka-Grande, but with a higher threshold of about 100 PeV. During the first stages of its operation, Tunka-Rex has proven, that sparse radio arrays can measure air-showers with an energy resolution of better than 15% and the depth of the shower maximum with a resolution of better than 40 g/cm2. To improve and interpret our measurements as well as to study systematic uncertainties due to interaction models, we perform radio simulations with CORSIKA and CoREAS. In this overview we present the setup of Tunka-Rex, discuss the achieved results and the prospects of mass-composition studies with radio arrays.

  20. Laryngopharyngeal Reflux: Diagnosis, Treatment, and Latest Research

    Directory of Open Access Journals (Sweden)

    Campagnolo, Andrea Maria

    2014-01-01

    Full Text Available Introduction Laryngopharyngeal reflux (LPR is a highly prevalent disease and commonly encountered in the otolaryngologist's office. Objective To review the literature on the diagnosis and treatment of LPR. Data Synthesis LPR is associated with symptoms of laryngeal irritation such as throat clearing, coughing, and hoarseness. The main diagnostic methods currently used are laryngoscopy and pH monitoring. The most common laryngoscopic signs are redness and swelling of the throat. However, these findings are not specific of LPR and may be related to other causes or can even be found in healthy individuals. Furthermore, the role of pH monitoring in the diagnosis of LPR is controversial. A therapeutic trial with proton pump inhibitors (PPIs has been suggested to be cost-effective and useful for the diagnosis of LPR. However, the recommendations of PPI therapy for patients with a suspicion of LPR are based on the results of uncontrolled studies, and high placebo response rates suggest a much more complex and multifactorial pathophysiology of LPR than simple acid reflux. Molecular studies have tried to identify biomarkers of reflux such as interleukins, carbonic anhydrase, E-cadherin, and mucin. Conclusion Laryngoscopy and pH monitoring have failed as reliable tests for the diagnosis of LPR. Empirical therapy with PPIs is widely accepted as a diagnostic test and for the treatment of LPR. However, further research is needed to develop a definitive diagnostic test for LPR.

  1. Latest results on $J/$ anomalous suppression

    Indian Academy of Sciences (India)

    Sérgio Ramos; NA50 Collaboration; B Allessandro; C Alexa; R Arnaldi; M Atayan; C Baglin; A Baldit; M Bedjidian; S Beolè; V Boldea; P Bordalo; S R Borenstein; G Borges; A Bussière; L Capelli; C Castanier; J Castor; B Chaurand; B Cheynis; E Chiavassa; C Cicalo; T Claudino; M P Comets; S Constantinescu; P Cortese; J Cruz; A DeFalco; N DeMarco; G Dellacasa; A Devaux; S Dita; O Drapier; B Espagnon; J Fargeix; P Force; M Gallio; Y K Gavrilov; C Gerschel; P Giubellino; M B Golubeva; M Gonin; A A Grigorian; S Grigorian; J Y Grossiord; F F Guber; A Guichard; H Gulkanyan; R Hakobyan; R Haroutunian; M Idzik; D Jouan; T L Karavitcheva; L Kluberg; A B Kurepin; Y Le Bornée; C Lourenço; P Macciotta; M Mac Cormick; A Marzari-Chiesa; M Masera; A Masoni; M Monteno; A Musso; P Petiau; A Piccotti; J R Pizzi; W L Prado da Silva; F Prino; G Puddu; C Quintans; L Ramello; S Ramos; P Rato Mendes; L Riccati; A Romana; H Santos; P Saturnini; E Scalas; E Scomparin; S Serci; R Shahoyan; F Sigaudo; M Sitta; P Sonderegger; X Tarrago; N S Topilskaya; G L Usai; E Vercellin; L Villatte; N Willis; T Wu

    2004-03-01

    The NA50 experiment deals with Pb–Pb collisions at 158 GeV/nucleon at the CERN SPS accelerator. The $J/$ production is studied through the muon decay channel, using the Drell–Yan dimuons as a reference. New results based on recent analyses, from data taken with improved experimental conditions and using different centrality estimators, are presented and compared to an update of those already obtained from previous data samples. The stepwise pattern of the anomalous $J/$ suppression as a function of centrality, already present in these previous results, is confirmed. This observation could be a fingerprint of the theoretically predicted melting of charmonia resonances in a deconfined quark–gluon plasma.

  2. Latest developments in silica fibre luminescence dosimetry

    Energy Technology Data Exchange (ETDEWEB)

    Bradley, D. A.; Abdul S, S. F.; Jafari, S. M.; Alanazi, A. [University of Surrey, Department of Physics, GU2 7XH Guildford, Surrey (United Kingdom); Amouzad M, G. [University of Malaya, Faculty of Engineering, Department of Electrical Engineering, Integrated Lightwave Research Group, 50603 Kuala Lumpur (Malaysia); Addul R, H. A.; Mizanur R, A. K. M.; Zubair, H. T.; Begum, M.; Yusoff, Z.; Omar, N. Y. M. [Multimedia University, Faculty of Engineering, 2010 Cyberjaya, Selangor (Malaysia); Maah, M. J. [University of Malaya, Department of Chemistry, 50603 Kuala Lumpur (Malaysia); Collin, S. [National Physical Laboratory, Hampton Road, Teddington, TW11 OLW Middlesex (United Kingdom); Mat-Sharif, K. A.; Muhd-Yassin, S. Z.; Zulkifli, M. I., E-mail: d.a.bradley@surrey.ac.uk [Telekom Malaysia Research and Development Sdn Bhd., 63000 Cyberjaya, Selangor (Malaysia)

    2015-10-15

    Full text: Using tailor made sub-mm diameter doped-silica fibres, we are carrying out luminescence dosimetry studies for a range of situations, including thermoluminescence (Tl)investigations on a liquid alpha source formed of {sup 223}RaCl (the basis of the Bayer Health care product Xofigo), the Tl response to a 62 MeV proton source and Tl response to irradiation from an {sup 241}Am-Be neutron source. In regard to the former, in accord with the intrinsic high linear energy transfer (Let) and short path length (<100 um) of the α-particles in calcified tissue, the product is in part intended as a bone-seeking radionuclide for treatment of metastatic cancer, offering high specificity and efficacy. The Tl yield of Ge-doped SiO{sub 2} fibres has been investigated including for photonic crystal fibre un collapsed, flat fibres and single mode fibres, these systems offering many advantages over conventional passive dosimetry types. In particular, one can mention comparable and even superior sensitivity, an effective atomic number Z{sub eff} of the silica dosimetric material close to that of bone, and the glassy nature of the fibres offering the additional advantage of being able to place such dosimeters directly into liquid environments. Finally we review the use of our tailor made fibres for on-line radioluminescence measurements of radiotherapy beams. The outcome from these various lines of research is expected to inform development of doped fiber radiation dosimeters of versatile utility, ranging from clinical applications through to industrial studies and environmental evaluations. (Author)

  3. Latest findings from the OECD Rasplav Project

    Energy Technology Data Exchange (ETDEWEB)

    Asmolov, V.

    1997-01-01

    During the late phase of a severe accident in a light water reactor (current and future designs of BWRs, PWRs and VVERs), a significant amount of core material may relocate downward to the lower head of the reactor vessel. If molten core materials were to relocate to the lower head of the reactor pressure vessel (RPV), a molten pool consisting primarily of a mixture of ZrO{sub 2} and UO{sub 2} and some combination of a metal would form on the lower head. A solid crust of material would form around the boundaries of the pool, but internal heat generation resulting from radioactive decay of fission products would assure that most of the pool remains molten. In fact, the molten pool would undergo significant internal natural convection which would reach steady state conditions in about a few hours. Detailed understanding of all aspects of this natural convection process, in conjunction with the thermal boundary conditions imposed on the outer surface, determines the fraction of the total heat dissipation that is transferred through the upper crust to the inside of the reactor vessel by radiative heat exchange and the fraction which must be conducted through the wall of the reactor vessel lower head. This distribution is critical in determining whether and under what conditions the molten material can be cooled and retained in the reactor pressure vessel. The OECD Rasplav Project was established in 1994 as a three year program to study molten pool behavior and its interactions with structural materials in the lower head. This paper reviews the establishment of the project, its initial studies and proposed experimental testing, and the construction, preparation, and actual testing of a chamber of corium heated to well above liquid temperature.

  4. Learning beyond the Classroom: Using Text Messages to Measure General Chemistry Students' Study Habits

    Science.gov (United States)

    Ye, Li; Oueini, Razanne; Dickerson, Austin P.; Lewis, Scott E.

    2015-01-01

    This study used a series of text message inquiries sent to General Chemistry students asking: "Have you studied for General Chemistry I in the past 48 hours? If so, how did you study?" This method for collecting data is novel to chemistry education research so the first research goals were to investigate the feasibility of the technique…

  5. Learning beyond the Classroom: Using Text Messages to Measure General Chemistry Students' Study Habits

    Science.gov (United States)

    Ye, Li; Oueini, Razanne; Dickerson, Austin P.; Lewis, Scott E.

    2015-01-01

    This study used a series of text message inquiries sent to General Chemistry students asking: "Have you studied for General Chemistry I in the past 48 hours? If so, how did you study?" This method for collecting data is novel to chemistry education research so the first research goals were to investigate the feasibility of the technique…

  6. Latest Developments of the Isprs Student Consortium

    Science.gov (United States)

    Detchev, I.; Kanjir, U.; Reyes, S. R.; Miyazaki, H.; Aktas, A. F.

    2016-06-01

    The International Society for Photogrammetry and Remote Sensing (ISPRS) Student Consortium (SC) is a network for young professionals studying or working within the fields of photogrammetry, remote sensing, Geographical Information Systems (GIS), and other related geo-spatial sciences. The main goal of the network is to provide means for information exchange for its young members and thus help promote and integrate youth into the ISPRS. Over the past four years the Student Consortium has successfully continued to fulfil its mission in both formal and informal ways. The formal means of communication of the SC are its website, newsletter, e-mail announcements and summer schools, while its informal ones are multiple social media outlets and various social activities during student related events. The newsletter is published every three to four months and provides both technical and experiential content relevant for the young people in the ISPRS. The SC has been in charge or at least has helped with organizing one or more summer schools every year. The organization's e-mail list has over 1,100 subscribers, its website hosts over 1,300 members from 100 countries across the entire globe, and its public Facebook group currently has over 4,500 joined visitors, who connect among one another and share information relevant for their professional careers. These numbers show that the Student Consortium has grown into a significant online-united community. The paper will present the organization's on-going and past activities for the last four years, its current priorities and a strategic plan and aspirations for the future four-year period.

  7. Apnea after Awake Regional and General Anesthesia in Infants: The General Anesthesia Compared to Spinal Anesthesia Study-Comparing Apnea and Neurodevelopmental Outcomes, a Randomized Controlled Trial

    National Research Council Canada - National Science Library

    Davidson, Anew J; Morton, Neil S; Arnup, Sarah J; de Graaff, Jurgen C; Disma, Nicola; Withington, Davinia E; Frawley, Geoff; Hunt, Rodney W; Hardy, Pollyanna; Khotcholava, Magda; von Ungern Sternberg, Britta S; Wilton, Niall; Tuo, Pietro; Salvo, Ida; Ormond, Gillian; Stargatt, Robyn; Locatelli, Bruno Guido; McCann, Mary Ellen; Absalom, Anthony

    2015-01-01

    ...) may reduce the risk; however, the evidence is weak. The General Anesthesia compared to Spinal anesthesia study is a randomized, controlled trial designed to assess the influence of general anesthesia (GA...

  8. (The latest developments of the physical aspects of electrochemistry)

    Energy Technology Data Exchange (ETDEWEB)

    Liu, S.H.

    1990-09-24

    The author was one of 26 invited lecturers to discuss the latest developments of the physical aspects of electrochemistry. He interacted extensively with other lecturers and many participants from developing countries. He also visited with the Director of the Italian Synchrotron Radiation Source now under construction in Trieste, Italy.

  9. Latest Higgs Physics Results with the ATLAS detector

    CERN Document Server

    Orestano, Domizia; The ATLAS collaboration

    2015-01-01

    This report presents the investigations on the recently discovered scalar boson by the ATLAS experiment at the CERN Large Hadron Collider. The latest results fully exploit the data collected during LHC Run 1 to measure the properties of the new boson and within the current sensitivity confirm the identification of this particle with the Higgs boson of the Standard Model.

  10. Latest Higgs Physics results from the ATLAS experiment

    CERN Document Server

    De Groot, Nicolo; The ATLAS collaboration

    2017-01-01

    Since the discovery in 2012, many measurements have been made on the production and prop- erties of the 125 GeV Higgs boson. The latest result from ATLAS will be presented, including recent results from run-1 at 8 TeV and some obtained in run-2 at 13 TeV.

  11. 78 FR 68469 - Draft General Management Plan/Wilderness Study/Environmental Impact Statement, Channel Islands...

    Science.gov (United States)

    2013-11-14

    ... National Park Service Draft General Management Plan/Wilderness Study/Environmental Impact Statement... availability of a Draft General Management Plan (GMP)/Wilderness Study/Environmental Impact Statement (EIS) for... action alternative) reflects current management direction and serves as a baseline for comparison with...

  12. Educational needs of general practitioners in palliative care : Outcome of a focus group study

    NARCIS (Netherlands)

    Meijler, WJ; Van Heest, F; Otter, R; Sleijfer, DT

    2005-01-01

    Background. The objective of this study was to identify the general practitioner's perception of educational needs in palliative care. Method. A qualitative study with focus groups was performed. Results. General practitioners estimate palliative care as an important and valuable part of primary car

  13. Ocean anoxia did not cause the Latest Permian Extinction

    Science.gov (United States)

    Proemse, Bernadette C.; Grasby, Stephen E.; Wieser, Michael E.; Mayer, Bernhard; Beauchamp, Benoit

    2014-05-01

    The Latest Permian Extinction (LPE, ~252 million years ago) was a turning point in the history of life on Earth with a loss of ~96% of all marine species and ~70% of all terrestrial species. While, the event undoubtedly shaped the evolution of life its cause remains enigmatic. A leading hypothesis is that the global oceans became depleted in oxygen (anoxia). In order to test this hypothesis we investigated a proxy for marine oxygen levels (molybdenum isotopic composition) in shale across the LPE horizon located on the subtropical northwest margin of Pangea at that time. We studied two sedimentary records in the Sverdrup basin, Canadian High Arctic: Buchanan Lake (eastern Axel Heiberg Island; 79° 26.1'N, 87° 12.6'W), representing a distal deep-water slope environment, and West Blind Fiord (southwest Ellesmere Island; 78° 23.9'N, 85° 57.2'W), representing a deep outer shelf environment (below storm wave base). The molybdenum isotopic composition (δ98/95Mo) of sediments has recently become a powerful tool as a paleo-oceanographic proxy of marine oxygen levels. Sample preparation was carried out in a metal-free clean room facility in the isotope laboratory of the Department of Physics and Astronomy, University of Calgary, Canada, that is supplied by HEPA-filtered air. Molybdenum isotope ratios were determined on a Thermo Scientific multi-collector inductively coupled plasma mass spectrometer (MC-ICP-MS) with an uncertainty better than ±0.10o for δ98/95Mo values. Results from the Buchanan Lake section show a large shift in δ98/95Mo values from 2.02o to +2.23o at the extinction horizon, consistent with onset of euxinic conditions. In contrast, West Blind Fiord shales, representing the sub-storm wave base shelf environment, show little change in the molybdenum isotopic composition (1.34o to +0.05), indicating ongoing oxic conditions across the LPE (Proemse et al., 2013). Our results suggest that areas of the Pangea continental shelf (North West Pangea) experienced

  14. Evaluation of CDA energetics in the prototype LMFBR with latest knowledge and tools

    Energy Technology Data Exchange (ETDEWEB)

    Tobita, Yoshiharu; Morita, Koji; Kawada, Ken-ichi; Niwa, Hajime; Nonaka, Nobuyuki [Japan Nuclear Cycle Development Institute, Oarai Engineering Center, Oarai, Ibaraki (Japan)

    1999-07-01

    The sequences of an unprotected loss-of-flow accident in the prototype LMFBR has been evaluated, as a part of reactor safety research, reflecting the latest experimental and analytical knowledge on core disruptive accident (CDA). In the evaluation, the event progression scenarios and the major physical parameters were selected, based on the latest experimental knowledge and code validation studies on the transient fuel behavior and material motion during the last decade, such that associated phenomenological uncertainties were well covered within physically reasonable ranges. With the safety research knowledge and advanced accident analysis codes, which have been made available lately, the CDA energetics was assessed to be much more benign in comparison with the former analysis. In other words, we have demonstrated that our former CDA analysis is sufficiently conservative. (author)

  15. Provision of medical student teaching in UK general practices: a cross-sectional questionnaire study

    Science.gov (United States)

    Harding, Alex; Rosenthal, Joe; Al-Seaidy, Marwa; Gray, Denis Pereira; McKinley, Robert K

    2015-01-01

    Background Health care is increasingly provided in general practice. To meet this demand, the English Department of Health recommends that 50% of all medical students should train for general practice after qualification. Currently 19% of medical students express general practice as their first career choice. Undergraduate exposure to general practice positively influences future career choice. Appropriate undergraduate exposure to general practice is therefore highly relevant to workforce planning Aim This study seeks to quantify current exposure of medical students to general practice and compare it with past provision and also with postgraduate provision. Design and setting A cross-sectional questionnaire in the UK. Method A questionnaire regarding provision of undergraduate teaching was sent to the general practice teaching leads in all UK medical schools. Information was gathered on the amount of undergraduate teaching, how this was supported financially, and whether there was an integrated department of general practice. The data were then compared with results from previous studies of teaching provision. The provision of postgraduate teaching in general practice was also examined. Results General practice teaching for medical students increased from teaching in 1968 to 13.0% by 2008; since then, the percentage has plateaued. The total amount of general practice teaching per student has fallen by 2 weeks since 2002. Medical schools providing financial data delivered 14.6% of the clinical curriculum and received 7.1% of clinical teaching funding. The number of departments of general practice has halved since 2002. Provision of postgraduate teaching has tripled since 2000. Conclusion Current levels of undergraduate teaching in general practice are too low to fulfil future workforce requirements and may be falling. Financial support for current teaching is disproportionately low and the mechanism counterproductive. Central intervention may be required to solve

  16. The Latest Study of Workplace Bullying and Anti-Bullying in American Libraries%美国图书馆工作场所欺凌和反欺凌现状最新调研

    Institute of Scientific and Technical Information of China (English)

    贺晶晶; 王颖纯; 刘燕权

    2015-01-01

    Workplace bullying has gradually become a hot research topic since 1980's, and it has also emerged as a prominent employment issue in many work environments. This study explored the status quo of library bullying incidents and corresponding solution in six US New England states. An electronic survey questionnaire was sent to 8000 library personnel. The data showed that among 570 participants 45.7% reported being bullied, in the midst of these bullied respondents 45.9%experienced at least three years or more and 25.5%left their current employers for the reason of workplace bullying. However, only 10% of 67 participated libraries reported they developed specific anti-bullying policies and regulations.%工作场所欺凌自80年代后逐渐成为职业研究领域的一个研究热点,也是许多工作环境普遍关注的研究课题. 文章对美国新英格兰六州的图书馆工作人员进行调研,探索了美国图书馆是否有发生欺凌事件的现状,以及是否有相应的解决政策. 问卷送至8000人左右,调查结果表明,在有效答复的570名受访者中45.7%称其经历过欺凌. 受欺凌者中45.9%称其经历欺凌持续了三年或更久,25.5%为此选择离开原工作岗位. 而另一方面受访的67所图书馆中仅有10%的图书馆制订了具体反欺凌的相关规章制度及政策.

  17. Differences in treatment approach between Dutch paediatric dentists and general practitioners, a case control study

    NARCIS (Netherlands)

    Kuin, D.; Veerkamp, J.S.J.

    2012-01-01

    AIM: This case control study was to assess whether paediatric dentists perform significantly more diagnostic, preventive and curative care in a clinical setting then do general dental practitioners. METHODS: 16 paediatric dentists were approached and a matching control group of 16 general dental pra

  18. Generalized Transition Network Parsing for Language Study: The GPARS System for English, Russian, Japanese, and Chinese.

    Science.gov (United States)

    Loritz, Donald

    1992-01-01

    GPARS is a generalized transition network system designed for language study by both students and researchers. It generalizes the Augmented Transition Network formalism by allowing top-down, bottom-up, depth-first, breadth-first, determininistic, and nondeterministic parsing strategies to be freely intermixed. (26 references) (Author/LB)

  19. A GENERAL SITE LOCATION STUDY FOR A REGIONAL COLLEGE FOR THE OKANAGAN AREA OF BRITISH COLUMBIA.

    Science.gov (United States)

    GILES, FREDERIC T.; AND OTHERS

    THE FEASIBILITY AND GENERAL SITE LOCATION OF A REGIONAL COLLEGE FOR TEN SCHOOL DISTRICTS IN THE OKANAGAN AREA OF BRITISH COLUMBIA WAS STUDIED AND ESTABLISHED. GEOGRAPHIC CENTERS OF POPULATION DISTRIBUTION, TRANSPORTATION, GENERAL ECONOMY AND SCHOOL POPULATIONS FOR GRADES 1-12 AND 13-14 WERE DETERMINED FROM THE ANALYSIS OF DEMOGRAPHIC, GEOGRAPHIC…

  20. Dynamics of Positive Interactions between General Education Students and Students with Special Needs: A Phenomenological Study

    Science.gov (United States)

    Rider, Brian J.

    2013-01-01

    This dissertation examined the dynamics of positive interactions between general education students and students with special needs in elementary inclusion-based physical education settings. More specifically, this qualitative study used a phenomenological research methodology aimed to examine the multiple factors contributing to general education…

  1. Latest Trends in Web Information Retrieval and in SEO Factors

    Directory of Open Access Journals (Sweden)

    Carlos Gonzalo

    2015-07-01

    Full Text Available Latest trends in web information retrieval and in  SEO factors, increasingly focused on signals from users as: profile of who performs the search and the interpretation of user intent. The objective of search engines is twofold: focusing at the maximum in the users and make ever less predictable the composition of the search engine result page (SERP , and  combating spam.

  2. mkt607 all week discussions latest 2015 [ all 16 discussions

    OpenAIRE

    Laynebaril

    2017-01-01

    mkt607 all week discussions latest 2015 [ all 16 discussions] Click Link Below To Buy:   http://hwcampus.com/shop/mkt607-all-week-discussions/   week 1   What are the components of a common marketing plan? Why is it important have a strategic marketing plan? How does the type of product or service affect the marketing strategy? Provide an example.       diss 2 What are the aspects of marketing management? How has the marketing management proc...

  3. Modelling and simulation SSM: latest state of the art technology

    CSIR Research Space (South Africa)

    Jahajeeah, N

    2005-10-01

    Full Text Available during filling stage Supporting the Manufacturing and Materials Industry in its quest for global competitiveness ? Shear rate history important factor in design and casting processes ? Viscosity decreases over time after applied shear rate ? Ideally... and Materials Industry in its quest for global competitiveness Modelling and Simulation SSM Latest state of the art technology N Jahajeeah Supporting the Manufacturing and Materials Industry in its quest for global competitiveness BEHAVIOUR OF THIXOTROPIC...

  4. Study of General health, resiliency, and defense mechanisms in patients with migraine headache

    Directory of Open Access Journals (Sweden)

    Alireza Aghayusefi

    2013-06-01

    Full Text Available Background: Migraine is a neurological disease that the etiology, several factors affect its onset or its exacerbation. One of the factors affecting disease is psychological factors such as defense mechanisms, resiliency, and general health. This study assessed the relationship between general health, resiliency, and general defense mechanisms, and also predicts the general health of people with migraine headaches that have a high resiliency and use mature defense mechanisms. Material and Methods: 50 women with migraine headache in the city of Bushehr using defense mechanisms, resiliency, and general health questionnaires were studied. For statistical analysis, Pearson correlation and multiple regression tests were used by SPSS 17 software. Results: The results showed that most of the defense mechanisms of migraine sufferers are Immature and Neuroticism. There is significant negative correlation between the deterioration of general health and resiliency as well as the mature defense mechanism (p=0/003, and also there is a significant positive correlation between this deterioration with neuroticism (p=0/040 and immature defense mechanisms (p=0/041. On the other hand there is significant negative correlation between resiliencies with immature (p=0/009 and neuroticism defense mechanisms (p=0/04, and also with mature defense mechanism has a significant positive correlation (p=0/003. Also, as more people use the mature defense mechanism, their deterioration of general health will be reduced, but this relationship will be stronger with the presence of resiliency. So migraine people use the mature defense mechanisms with high resiliency will have more favorable general health (less deterioration of general health. Conclusion: This study showed that migraine patients use the mature defense mechanisms with high resiliency will have more favorable general health (less deterioration of general health.

  5. Relationships of approaches to studying, metacognition, and intellectual development of general chemistry students

    Science.gov (United States)

    Egenti, Henrietta N.

    This study investigated approaches to studying, intellectual developments, and metacognitive skills of general chemistry students enrolled for the spring 2011 semester at a single campus of a multi-campus community college. The three instruments used were the Approaches and Study Skills Inventory for Students (ASSIST), the Learning Environment Preferences (LEP), and the Executive Process Questionnaire (EPQ). The subjects were 138 students enrolled in either general chemistry 1 or 2. The results revealed that the preferred approach to study was the strategic approach. The intellectual development of the students was predominantly Perry's position 2 (dualist) in transition to position 3 (multiplicity). Correlation statistics revealed that deep approach to studying is related to effective employment of metacognitive skills. Students with a deep approach to studying were likely to utilize effective metacognitive skills. Students with a surface approach to studying used no metacognitive skills or ineffective metacognitive skills. Multiple logistic regression analysis was conducted to ascertain which of the three variables, namely approaches to studying, ability to metacognate, or level of intellectual development, was the most salient in predicting the success of general chemistry students. No single variable was found to predict students’ success in general chemistry classes; however, a surface approach to studying predisposes general chemistry students to fail. The implication of this study is that students’ study approaches, intellectual developments, and metacognitive skills are requisite information to enable instructional remediation early in the semester.

  6. The "RG Sausage's" Missing Ingredients: Investigating the Validity of Reliability Generalization Study Design.

    Science.gov (United States)

    Romano, Jeanine; Kromrey, Jeffrey D.

    The purpose of this study was to examine the potential impact of selected methodological factors on the validity of conclusions from reliability generalization (RG) studies. The study focused on four factors; (1) missing data in the primary studies; (2) transformation of sample reliability estimates; (3) use of sample weights for estimating mean…

  7. STUDY OF THE EQUIVALENT THEOREM OF GENERALIZED VARIATIONAL PRINCIPLES IN ELASTICITY

    Institute of Scientific and Technical Information of China (English)

    张国清; 余建星

    2004-01-01

    The relations of all generalized variational principles in elasticity are studied by employing the invariance theorem of field theory. The infinitesimal scale transformation in field theory was employed to investigate the equivalent theorem. Among the results found particularly interesting are those related to that all generalized variational principles in elasticity are equal to each other. Also studied result is that only two variables are independent in the functional and the stress-strain relation is the variational constraint condition for all generalized variational principles in elasticity. This work has proven again the conclusion of Prof. Chien Wei-zang.

  8. The role of Riemann generalized derivative in the study of qualitative properties of functions

    Directory of Open Access Journals (Sweden)

    Sorin Radulescu

    2013-08-01

    Full Text Available Marshal Ash [3] introduced the concept of (sigma,tau differentiable functions and studied the Riemann generalized derivatives In this article we study the convexity and monotonicity of (sigma,tau differentiable functions, using results by Hincin, Humke and Laczkovich, and using the Riemann generalized derivative. We give conditions such that the classic properties of differentiable functions hold also for (sigma,tau differentiable functions.

  9. The latest treatment strategy for the rheumatoid hand deformity.

    Science.gov (United States)

    Ishikawa, Hajime

    2017-07-01

    With a remarkable improvement in the pharmacotherapy of rheumatoid arthritis (RA), severely handicapped patients are very rare to see. Healing, repair and drug-free, and toward radical cure are coming to be possible. In the clinical practice, more than 50% of the patients are in remission. However, some patients are still difficult to reach remission due to comorbidities and economic burden. In the patient with clinical remission, smoldering synovitis so called "silent destructor" is often detected by ultrasonograpy or by synovial histology in the small joints of the hand. In recent years, over use with "no pain" increases the risk of deformity, osteoarthrosis, tendon rupture and entrapment neuropathy. Highly motivated patients, who concern about the appearance of the hand, hope to get a higher level of activities of daily living and quality of life (QOL). A prospective cohort study was performed for the purpose of knowing whether rheumatoid hand surgery affects the patient's QOL and mental health as well as upper extremity function. A primary hand surgery was scheduled in 119 patients with RA. Synovectomy and Darrach procedure, radiolunate arthrodesis, reconstruction of the extensor tendons, arthroplasty at the metacarpophalangeal (MP) using Swanson implant, fusion at the proximal interphalangeal (PIP) joint, suspensionplasty at the carpometacarpal (CM) joint of the thumb (Thompson method) et al. were performed. As a result, Japanese version of the Stanford Health Assessment Questionnaire (J-HAQ:physical function,QOL), EuroQOL-5 dimension (EQ-5D:QOL), Beck Depression Inventory-II (BDI-II:depression, mentality) at 6 months and at 12 months after surgery improved significantly compared to those just before surgery (p < 0.01). Disease activity score 28- C reactive protein 4 (DAS28-CRP (4)) decreased significantly (p < 0.01). Latest hand surgery with tight medical control is possible to raise QOL and to provide mental wellness for the patient with RA. Copyright

  10. 清末新学制下的《最新中学教科书几何学·立体部》研究%A Study of The Latest Middle School Solid Geometry Textbook Under the Background of the New Educational System in the Late Qing Dynasty

    Institute of Scientific and Technical Information of China (English)

    王靖宇

    2011-01-01

    清末新学制的颁布有力地促进了教育由传统向近代的转化,国人开始自行翻译和编译新式的中小学教科书.介绍了清末新学制颁布后第一套新式教科书之一——《最新中学教科书几何学·立体部》的编译者谢洪赉的生平,阐述了新式立体几何教科书的编译背景、编写理念、编排形式、主要内容和名词术语,以及该书的编写特点.%The promulgation of the new educational system in the late Qing Dynasty stimulated greatly the transformation of Chinese education from traditional to modern, so that some new primary and secondary school textbooks were compiled or translated. This paper deals with The latest middle school Solid geometry text book, which was one of the first new textbooks for high school students after the new educational system issued in late Qing dynasty,studying the background of writing the textbook,and its compilation idea, its content, symbols and the characteristics,as well as the author Xie Honglai's lifetime.

  11. Private or salaried practice: how do young general practitioners make their career choice? A qualitative study.

    Science.gov (United States)

    Kinouani, Shérazade; Boukhors, Gary; Luaces, Baptiste; Durieux, William; Cadwallader, Jean-Sébastien; Aubin-Auger, Isabelle; Gay, Bernard

    2016-09-01

    Young French postgraduates in general practice increasingly prefer salaried practice to private practice in spite of the financial incentives offered by the French government or local communities to encourage the latter. This study aimed to explore the determinants of choice between private or salaried practice among young general practitioners. A qualitative study was conducted in the South West of France. Semi-structured interviews of young general practitioners were audio-recorded until data saturation. Recordings were transcribed and then analyzed according to Grounded Theory by three researchers working independently. Sixteen general practitioners participated in this study. For salaried and private doctors, the main factors governing their choice were occupational factors: working conditions, need of varied scope of practice, quality of the doctor-patient relationship or career flexibility. Other factors such as postgraduate training, having worked as a locum or self-interest were also determining. Young general practitioners all expected a work-life balance. The fee-for-service scheme or home visits may have discouraged young general practitioners from choosing private practice. National health policies should increase the attractiveness of ambulatory general practice by promoting the diversification of modes of remuneration and encouraging the organization of group exercises in multidisciplinary medical homes and community health centers.

  12. Case Studies of Mental Health in General practice(28)---HIV and Mood Disturbance

    Institute of Scientific and Technical Information of China (English)

    Fiona Judd; Leon Piterman; Grant Blashki; Hui Yang

    2014-01-01

    The Journal presents the Column of Case Studies of Mental Health in General Practice;with aca-demic support from Australian eXperts in general practice,psychology and psychiatry from Monash University and the University of Mel-bourne. The Columnˊs purpose is to respond to the increasing need for the development of mental health services in China. Through study and analysis of mental health cases,we hope to improve understanding of mental illnesses in Chinese primary health settings,and to build capaci-ty amongst community health professionals in managing mental illnesses and psychological problems in general practice. A patient - centred whole - person approach in general practice is the best way to maintain and improve the physical and mental health of residents. Our hope is that these case studies will lead the new wave of general practice and mental health service development both in practice and research. A num-ber of Australian eXperts from the disciplines of general practice,mental health and psychiatry will contribute to the Column. Professor Blash-ki,Professor Judd and Professor Piterman are authors of the teXt General Practice Psychiatry;the Chinese version of the book to be published in 2014. The Journal cases are helping to prepare for the translation and publication of a Chinese version of the book in China. We believe Chi-nese mental health in primary health care will reach new heights under this international cooperation.

  13. Survey of Latest Wireless Cellular Technologies for Enhancement of Spectral Density at Reduced Cost

    CERN Document Server

    Jain, R K; Agrawal, N K

    2011-01-01

    The future of mobile wireless communication networks will include existing 3rd generation, 4th generation (implemented in Japan, USA, South Korea etc.), 5th generation (based on cognitive radio which implies the whole wireless world interconnection & WISDOM - Wireless innovative System for Dynamic Operating Megacommunications concept), 6th generation (with very high data rates Quality of Service (QoS) and service applications) and 7th generation (with space roaming). This paper is focused on the specifications of future generations and latest technologies to be used in future wireless mobile communication networks. However keeping in view the general poor masses of India, some of the future generation technologies will be embedded with 2G and 2.5G so that general masses may get the advantage of internet, multimedia services and the operators may get proper revenues with little extra expenditure in the existing mobile communication networks.

  14. Relationships of Approaches to Studying, Metacognition, and Intellectual Development of General Chemistry Students

    Science.gov (United States)

    Egenti, Henrietta N.

    2012-01-01

    This study investigated approaches to studying, intellectual developments, and metacognitive skills of general chemistry students enrolled for the spring 2011 semester at a single campus of a multi-campus community college. The three instruments used were the Approaches and Study Skills Inventory for Students (ASSIST), the Learning Environment…

  15. Course and prognosis of older back pain patients in general practice : A prospective cohort study

    NARCIS (Netherlands)

    Scheele, Jantine; Enthoven, Wendy T. M.; Bierma-Zeinstra, Sita M. A.; Peul, Wilco C.; van Tulder, Maurits W.; Bohnen, Arthur M.; Berger, Marjolein Y.; Koes, Bart W.; Luijsterburg, Pim A. J.

    2013-01-01

    The aim of the current study was to determine the course of back pain in older patients and identify prognostic factors for non-recovery at 3 months' follow-up. We conducted a prospective cohort study (the BACE study) of patients aged >55 years visiting a general practitioner (GP) with a new episode

  16. Relationships of Approaches to Studying, Metacognition, and Intellectual Development of General Chemistry Students

    Science.gov (United States)

    Egenti, Henrietta N.

    2012-01-01

    This study investigated approaches to studying, intellectual developments, and metacognitive skills of general chemistry students enrolled for the spring 2011 semester at a single campus of a multi-campus community college. The three instruments used were the Approaches and Study Skills Inventory for Students (ASSIST), the Learning Environment…

  17. The structure of psychopathology in adolescence : Replication of a general psychopathology factor in the TRAILS study

    NARCIS (Netherlands)

    Laceulle, O.M.; Vollebergh, W.A.M.; Ormel, J.

    2015-01-01

    This study aimed to replicate a study by Caspi and colleagues, which proposed that the structure of psychopathology is characterized by a general psychopathology factor, in addition to smaller internalizing and externalizing factors. Our study expanded the approach of the original by using

  18. The factors associated to psychosocial stress among general practitioners in Lithuania. Cross-sectional study

    Directory of Open Access Journals (Sweden)

    Vanagas Giedrius

    2005-06-01

    Full Text Available Abstract Background There are number of studies showing that general practice is one of the most stressful workplace among health care workers. Since Baltic States regained independence in 1990, the reform of the health care system took place in which new role and more responsibilities were allocated to general practitioners' in Lithuania. This study aimed to explore the psychosocial stress level among Lithuanian general practitioner's and examine the relationship between psychosocial stress and work characteristics. Methods The cross-sectional study of 300 Lithuanian General practitioners. Psychosocial stress was investigated with a questionnaire based on the Reeder scale. Job demands were investigated with the R. Karasek scale. The analysis included descriptive statistics; interrelationship analysis between characteristics and multivariate logistic regression to estimate odds ratios for each of the independent variables in the model. Results Response rate 66% (N = 197. Our study highlighted highest prevalence of psychosocial stress among widowed, single and female general practitioners. Lowest prevalence of psychosocial stress was among males and older age general practitioners. Psychosocial stress occurs when job demands are high and job decision latitude is low (χ2 = 18,9; p Conclusion One half of respondents suffering from work related psychosocial stress. High psychological workload demands combined with low decision latitude has the greatest impact to stress caseness among GP's. High job demands, high patient load and young age of GP's can be assigned as significant predictors of psychosocial stress among GP's.

  19. Old persons' contact with general practitioners in relation to health: a Danish population study

    DEFF Research Database (Denmark)

    Almind, G; Holstein, B E; Holst, E;

    1991-01-01

    The study describes health, social situation, and contact with general practitioners in a random sample of non-institutionalized persons 70-95 years old in Denmark. There was a strong correlation between health and contact with general practitioners. A small group, 3% of the respondents, had...... no health problems, but had been in contact with a general practitioner within the previous month. This group was characterized by a strong social network and a high degree of life satisfaction. Another small group, including 3% of the respondents, had extensive health problems, but had nevertheless...

  20. Some studies on mathematical models for general elastic multi-structures

    Institute of Scientific and Technical Information of China (English)

    HUANG Jianguo; SHI Zhongci; XU Yifeng

    2005-01-01

    The aim of this paper is to study the static problem about a general elastic multi-structure composed of an arbitrary number of elastic bodies, plates and rods. The mathematical model is derived by the variational principle and the principle of virtual work in a vector way. The unique solvability of the resulting problem is proved by the Lax-Milgram lemma after the presentation of a generalized Korn's inequality on general elastic multi-structures. The equilibrium equations are obtained rigorously by only assuming some reasonable regularity of the solution. An important identity is also given which is essential in the finite element analysis for the problem.

  1. Possible relations between general population suicide rates and societal crime: a cross-national study.

    Science.gov (United States)

    Shah, Ajit; Bhandarkar, Ritesh

    2008-10-01

    Crime may be associated with a less structured society, less social integration, and feelings of less security and greater distress among citizens, which characteristics may lead to mental illness and subsequent suicide. Therefore, a cross-national analysis examining the association of general population suicide rates with percent of males and females in the population victimised by different categories of crime was undertaken using cross-national data from the World Health Organization and United Nations for 42 countries. Spearman correlations were generally weak and not statistically significant. Those values were at variance with the study's hypothesis and may be explained by several factors, including methodological issues. Individual-level case-control or cohort studies of suicides and attempted suicides in the general population may permit exploration of the relation of general population suicides with experience and percent by nations of being victimised by crime.

  2. Studies on Santilli's Locally Anisotropic and Inhomogeneous Isogeometries; 1, Isobundles and Generalized Isofinsler Geometry

    CERN Document Server

    Vacaru, S I

    1997-01-01

    We generalize the geometry of Santilli's locally anisotropic and inhomogeneous isospaces to the geometry of vector isobundles provided with nonlinear and distinguished isoconnections and isometric structures. We present, apparently for the first time, the isotopies of Lagrange, Finsler and Kaluza-Klein spaces. We also continue the study of the interior, locally anisotropic and inhomogeneous gravitation by extending the isoriemannian space's constructions and presenting a geometric background for the theory of isofield interactions in generalized isolagrange and isofinsler spaces.

  3. Determinants of general practitioner’s cancer related gut feelings – a prospective cohort study

    OpenAIRE

    Donker, G.; Wiersma, E.; Heins, M.

    2016-01-01

    Background General practitioners (GPs) use gut feelings to diagnose cancer in an early stage, but little is known about the predictive value of gut feelings and how this is influenced by patient and GP characteristics. Methods Prospective cohort study of patients in 44 general practices throughout the Netherlands, from January 2010 till December 2013. GPs completed a questionnaire regarding gut feelings, patient and GP characteristics, if they noticed a cancer-related gut feeling during patie...

  4. Prevalence of burnout among Irish general practitioners: a cross-sectional study.

    Science.gov (United States)

    O'Dea, B; O'Connor, P; Lydon, S; Murphy, A W

    2017-05-01

    Burnout constitutes a significant problem among physicians which impacts negatively upon both the doctor and their patients. Previous research has indicated that burnout is prevalent among primary care physicians in other European countries and North America. However, there is a paucity of research assessing burnout among Irish general practitioners and examining predictive factors. To report the findings of a survey of burnout among Irish general practitioners, and assess variables related to burnout in this population. An online, anonymous questionnaire was distributed to general practitioners working in the Republic of Ireland. In total, 683 general practitioners (27.3 % of practising Irish general practitioners) completed the survey. Of these, 52.7 % reported high levels of emotional exhaustion, 31.6 % scored high on depersonalisation and 16.3 % presented with low levels of personal accomplishment. In total, 6.6 % presented with all three symptoms, fulfilling the criteria for burnout. Emotional exhaustion was higher among this sample than that reported in European and UK studies of burnout in general practitioners. Personal accomplishment was, however, higher in this sample than in other studies. Multiple regression analyses revealed that younger age, non-principal status role, and male gender were related to increased risk of burnout symptoms. The symptoms of burnout appear prevalent among Irish general practitioners. This is likely to have a detrimental impact both upon the individual general practitioners and the patients that they serve. Research investigating the factors contributing to burnout in this population, and evaluating interventions to improve general practitioner well-being, is, therefore, essential.

  5. The process of patient enablement in general practice nurse consultations: a grounded theory study.

    Science.gov (United States)

    Desborough, Jane; Banfield, Michelle; Phillips, Christine; Mills, Jane

    2017-05-01

    The aim of this study was to gain insight into the process of patient enablement in general practice nursing consultations. Enhanced roles for general practice nurses may benefit patients through a range of mechanisms, one of which may be increasing patient enablement. In studies with general practitioners enhanced patient enablement has been associated with increases in self-efficacy and skill development. This study used a constructivist grounded theory design. In-depth interviews were conducted with 16 general practice nurses and 23 patients from 21 general practices between September 2013 - March 2014. Data generation and analysis were conducted concurrently using constant comparative analysis and theoretical sampling focussing on the process and outcomes of patient enablement. Use of the storyline technique supported theoretical coding and integration of the data into a theoretical model. A clearly defined social process that fostered and optimised patient enablement was constructed. The theory of 'developing enabling healthcare partnerships between nurses and patients in general practice' incorporates three stages: triggering enabling healthcare partnerships, tailoring care and the manifestation of patient enablement. Patient enablement was evidenced through: 1. Patients' understanding of their unique healthcare requirements informing their health seeking behaviours and choices; 2. Patients taking an increased lead in their partnership with a nurse and seeking choices in their care and 3. Patients getting health care that reflected their needs, preferences and goals. This theoretical model is in line with a patient-centred model of health care and is particularly suited to patients with chronic disease. © 2016 John Wiley & Sons Ltd.

  6. Latest results from the ARGO-YBJ experiment

    CERN Document Server

    Di Sciascio, Giuseppe

    2015-01-01

    The ARGO-YBJ experiment has been in stable data taking for 5 years at the YangBaJing Cosmic Ray Observatory (Tibet, P.R. China, 4300 m a.s.l., 606 g/cm$^2$). With a duty-cycle greater than 86\\% the detector collected about 5$\\times $10$^{11}$ events in a wide energy range, from few hundreds GeV up to about 10 PeV. A number of open problems in cosmic ray physics has been faced exploiting different analyses. In this paper we summarize the latest results in cosmic ray physics and in gamma-ray astronomy.

  7. Latest AMS Results on elementary particles in cosmic rays

    Science.gov (United States)

    Kounine, Andrei; AMS Collaboration

    2017-01-01

    AMS-02 is a particle physics detector collecting data on the International Space Station since May 2011. Precision measurements of all elementary charged cosmic ray particles have been performed by AMS using a data sample of 85 billion cosmic ray events collected during the first five years of operations on the Station. The latest AMS results on the fluxes and flux ratios of the elementary cosmic ray particles are presented. They show unique features that require accurate theoretical interpretation as to their origin, be it from dark matter collisions or new astrophysical sources. On behalf of the AMS Collaboration.

  8. Constraining interacting dark energy models with latest cosmological observations

    Science.gov (United States)

    Xia, Dong-Mei; Wang, Sai

    2016-11-01

    The local measurement of H0 is in tension with the prediction of Λ cold dark matter model based on the Planck data. This tension may imply that dark energy is strengthened in the late-time Universe. We employ the latest cosmological observations on cosmic microwave background, the baryon acoustic oscillation, large-scale structure, supernovae, H(z) and H0 to constrain several interacting dark energy models. Our results show no significant indications for the interaction between dark energy and dark matter. The H0 tension can be moderately alleviated, but not totally released.

  9. Latest nH analysis in the Double Chooz experiment

    CERN Document Server

    Yang, Guang

    2015-01-01

    Precise measurement of the neutrino mixing angle $\\theta_{13}$ is the primary goal of the Double Chooz Experiment (DC), which is located in Chooz, France. The inverse beta decay process provides a unique signature of reactor anti-neutrino interactions, giving prompt signals from positron annihilation and delayed signals from neutron capture by either Gadolinium (Gd) or Hydrogen (H). This paper is dedicated to the latest nH analysis in Double Chooz. Typically, The Gd analysis is primary since fewer background events are involved. However, with accurate estimates of backgrounds and a precise reconstruction of energy, the nH analysis gives a powerful independent measurement of $\\theta_{13}$.

  10. Constraining interacting dark energy models with latest cosmological observations

    CERN Document Server

    Xia, Dong-Mei

    2016-01-01

    The local measurement of $H_0$ is in tension with the prediction of $\\Lambda$CDM model based on the Planck data. This tension may imply that dark energy is strengthened in the late-time Universe. We employ the latest cosmological observations on CMB, BAO, LSS, SNe, $H(z)$ and $H_0$ to constrain several interacting dark energy models. Our results show no significant indications for the interaction between dark energy and dark matter. The $H_0$ tension can be moderately alleviated, but not totally released.

  11. The neutron decay spectrometer aSPECT: Latest results

    Energy Technology Data Exchange (ETDEWEB)

    Wirth, Hans-Friedrich; Angerer, Heinz; Konorov, Igor; Petzoldt, Gerd; Simson, Martin; Zimmer, Oliver [Physik-Department, Technische Universtitaet Muenchen (Germany); Ayala Guardia, Fidel; Borg, Michael; Glueck, Ferenc; Heil, Werner; Konrad, Gertrud; Munoz Horta, Raquel; Sobolev, Yury [Institut fuer Physik, Universitaet Mainz (Germany); Baessler, Stefan [Department of Physics, University of Virginia, Charlottesville (United States); Eberhardt, Klaus [Institut fuer Kernchemie, Universitaet Mainz (Germany)

    2008-07-01

    The neutron decay spectrometer aSPECT was designed to measure accurately the proton spectrum of the free neutron decay. The knowledge of the proton spectrum allows to extract the neutrino electron angular correlation coefficient a, from which we will determine with highest accuracy the ratio {lambda}= g{sub A}/g{sub V} of the weak coupling constants of the nucleon. After successful beamtimes in 2005/06 at the FRM-II near Munich we continue the measurements at the ILL in Grenoble. Latest results and experiences with a new proton detector, which is a silicon drift detector, are presented.

  12. Apnea after Awake Regional and General Anesthesia in Infants : The General Anesthesia Compared to Spinal Anesthesia Study-Comparing Apnea and Neurodevelopmental Outcomes, a Randomized Controlled Trial

    NARCIS (Netherlands)

    Davidson, Andrew J.; Morton, Neil S.; Arnup, Sarah J.; De Graaff, Jurgen C.|info:eu-repo/dai/nl/249966271; Disma, Nicola; Withington, Davinia E.; Frawley, Geoff; Hunt, Rodney W.; Hardy, Pollyanna; Khotcholava, Magda; Von Ungern Sternberg, Britta S.; Wilton, Niall; Tuo, Pietro; Salvo, Ida; Ormond, Gillian; Stargatt, Robyn; Locatelli, Bruno Guido; McCann, Mary Ellen; Lee, Katherine; Sheppard, Suzette; Hartmann, Penelope; Ragg, Philip; Backstrom, Marie; Costi, David; Von Ungern-Sternberg, Britta S.; Knottenbelt, Graham; Montobbio, Giovanni; Mameli, Leila; Giribaldi, Gaia; Prato, Alessio Pini; Mattioli, Girolamo; Wolfler, Andrea; Izzo, Francesca; Sonzogni, Valter; Van Gool, Jose T D G; Numan, Sandra C.; Kalkman, Cor J.; Hagenaars, J. H M; Absalom, Anthony R.; Hoekstra, Frouckje M.; Volkers, Martin J.; Furue, Koto; Gaudreault, Josee; Berde, Charles; Soriano, Sulpicio; Young, Vanessa; Sethna, Navil; Kovatsis, Pete; Cravero, Joseph P.; Bellinger, David; Marmor, Jacki; Lynn, Anne; Ivanova, Iskra; Hunyady, Agnes; Verma, Shilpa; Polaner, David; Thomas, Joss; Meuller, Martin; Haret, Denisa; Szmuk, Peter; Steiner, Jeffery; Kravitz, Brian; Suresh, Santhanam; Hays, Stephen R.; Taenzer, Andreas H.; Maxwell, Lynne G.; Williams, Robert K.; Bell, Graham T.; Dorris, Liam; Adey, Claire; Bagshaw, Oliver; Chisakuta, Anthony; Eissa, Ayman; Stoddart, Peter; Davis, Annette; Myles, Paul; Wolf, Andy; McIntosh, Neil; Carlin, John; Leslie, Kate; De Lima, Jonathan; Hammer, Greg; Field, David; Gebski, Val; Tibboel, Dick

    2015-01-01

    Background: Postoperative apnea is a complication in young infants. Awake regional anesthesia (RA) may reduce the risk; however, the evidence is weak. The General Anesthesia compared to Spinal anesthesia study is a randomized, controlled trial designed to assess the influence of general anesthesia (

  13. Apnea after Awake Regional and General Anesthesia in Infants : The General Anesthesia Compared to Spinal Anesthesia Study-Comparing Apnea and Neurodevelopmental Outcomes, a Randomized Controlled Trial

    NARCIS (Netherlands)

    Davidson, Andrew J; Morton, Neil S; Arnup, Sarah J; de Graaff, Jurgen C; Disma, Nicola; Withington, Davinia E; Frawley, Geoff; Hunt, Rodney W; Hardy, Pollyanna; Khotcholava, Magda; von Ungern Sternberg, Britta S; Wilton, Niall; Tuo, Pietro; Salvo, Ida; Ormond, Gillian; Stargatt, Robyn; Locatelli, Bruno Guido; McCann, Mary Ellen; Absalom, Anthony

    2015-01-01

    BACKGROUND: Postoperative apnea is a complication in young infants. Awake regional anesthesia (RA) may reduce the risk; however, the evidence is weak. The General Anesthesia compared to Spinal anesthesia study is a randomized, controlled trial designed to assess the influence of general anesthesia (

  14. Apnea after Awake Regional and General Anesthesia in Infants : The General Anesthesia Compared to Spinal Anesthesia Study-Comparing Apnea and Neurodevelopmental Outcomes, a Randomized Controlled Trial

    NARCIS (Netherlands)

    Davidson, Andrew J.; Morton, Neil S.; Arnup, Sarah J.; De Graaff, Jurgen C.; Disma, Nicola; Withington, Davinia E.; Frawley, Geoff; Hunt, Rodney W.; Hardy, Pollyanna; Khotcholava, Magda; Von Ungern Sternberg, Britta S.; Wilton, Niall; Tuo, Pietro; Salvo, Ida; Ormond, Gillian; Stargatt, Robyn; Locatelli, Bruno Guido; McCann, Mary Ellen; Lee, Katherine; Sheppard, Suzette; Hartmann, Penelope; Ragg, Philip; Backstrom, Marie; Costi, David; Von Ungern-Sternberg, Britta S.; Knottenbelt, Graham; Montobbio, Giovanni; Mameli, Leila; Giribaldi, Gaia; Prato, Alessio Pini; Mattioli, Girolamo; Wolfler, Andrea; Izzo, Francesca; Sonzogni, Valter; Van Gool, Jose T D G; Numan, Sandra C.; Kalkman, Cor J.; Hagenaars, J. H M; Absalom, Anthony R.; Hoekstra, Frouckje M.; Volkers, Martin J.; Furue, Koto; Gaudreault, Josee; Berde, Charles; Soriano, Sulpicio; Young, Vanessa; Sethna, Navil; Kovatsis, Pete; Cravero, Joseph P.; Bellinger, David; Marmor, Jacki; Lynn, Anne; Ivanova, Iskra; Hunyady, Agnes; Verma, Shilpa; Polaner, David; Thomas, Joss; Meuller, Martin; Haret, Denisa; Szmuk, Peter; Steiner, Jeffery; Kravitz, Brian; Suresh, Santhanam; Hays, Stephen R.; Taenzer, Andreas H.; Maxwell, Lynne G.; Williams, Robert K.; Bell, Graham T.; Dorris, Liam; Adey, Claire; Bagshaw, Oliver; Chisakuta, Anthony; Eissa, Ayman; Stoddart, Peter; Davis, Annette; Myles, Paul; Wolf, Andy; McIntosh, Neil; Carlin, John; Leslie, Kate; De Lima, Jonathan; Hammer, Greg; Field, David; Gebski, Val; Tibboel, Dick

    2015-01-01

    Background: Postoperative apnea is a complication in young infants. Awake regional anesthesia (RA) may reduce the risk; however, the evidence is weak. The General Anesthesia compared to Spinal anesthesia study is a randomized, controlled trial designed to assess the influence of general anesthesia (

  15. [Current controversies in glycemic control targets. What do the results of the latest clinical trials tell us about the approach to type 2 diabetes mellitus?].

    Science.gov (United States)

    Mauricio, Dídac; Rius, Ferran

    2010-09-01

    The aim of this article is to discuss the implications of the results obtained in the latest large-scale clinical trials designed to evaluate the effect of intensive glycemic control on the vascular complications associated with type 2 diabetes mellitus. The current scientific evidence is reviewed and the implications of the ACCORD (The Action to Control Cardiovascular Risk in Diabetes study group), ADVANCE (Action in Diabetes and Vascular disease: Preterax and Diamicron Modified Release Control Evaluation) and VADT (Veterans Affairs Diabetes Trial) clinical trials are discussed. General concerns of the studies and their implications for clinical practice and the management of type 2 diabetes, as well as the questions which still need to be answered by future clinical research are discussed.

  16. Reinforced racial integration in the first grade: a study in generalization.

    Science.gov (United States)

    Hauserman, N; Walen, S R; Behling, M

    1973-01-01

    This study investigated possible factors in promoting racial integration, a matter of practical concern in schools today. Specifically, the effect of social and tangible reinforcement was studied on the social integration of five black children in a predominantly white classroom. "Sitting and seating with a new friend" in the school cafeteria was manipulated by (a) teacher directive combined with reinforcement and (b) by positive reinforcement alone. Treatment effectiveness was studied in the cafeteria and as generalization effects to a free-play period. The results indicated that reinforcement produced significant generalization to integrated free play, although intersubject variability was present. Evidence suggests that reinforcement techniques can be used effectively to promote social integration.

  17. Developing COPD: a 25 year follow up study of the general population

    DEFF Research Database (Denmark)

    Løkke, Anders; Lange, Peter; Scharling, H

    2006-01-01

    BACKGROUND: Smokers are more prone to develop chronic obstructive pulmonary disease (COPD) than non-smokers, but this finding comes from studies spanning 10 years or less. The aim of this study was to determine the 25 year absolute risk of developing COPD in men and women from the general populat...

  18. Influence of public alcohol and tobacco use on general practitioners' advice: an international comparative study.

    NARCIS (Netherlands)

    Pas, L.; Boerma, W.; Spreeuwenberg, P.; Saunders, J.B.; Zee, J. van der

    2002-01-01

    Background: Efficacy of advice for substance use is proven in general practice. Studies show high variability of perfomance. Especially intercountry variability has rarely been taken into account. Aim: To study the influence of public tobacco and alcohol use and health service characteristics on the

  19. A cost study of a general practitioner hospital in the Netherlands.

    NARCIS (Netherlands)

    Hakkart-van Roijen, L.; Moll van Charante, E.P.; Bindels, P.J.E.; Yzermans, C.J.; Rutten, F.F.H.

    2004-01-01

    To perform a cost study of the first general practitioner (GP) hospital in the Netherlands. We conducted a cost study in a GP hospital in the Netherlands. Data on healthcare utilisation from 218 patients were collected for a period of one year. The costs of admission to the GP hosptial were compared

  20. Incidence of open-angle glaucoma in a general elderly population - The Rotterdam Study

    NARCIS (Netherlands)

    de Voogd, S; Ikram, MK; Wolfs, RCW; Jansonius, NM; Hofman, A; de Jong, PTVM

    2005-01-01

    Purpose: To determine the incidence of open-angle glaucoma (OAG) in a general elderly white population. Design: Population-based cohort study. Participants: Participants 55 years and older from the Rotterdam Study, The Netherlands. Methods: Participants at risk for incident OAG underwent at baseline

  1. Major General Spurgeon Neel and the Army Physician Assistant: A Case Study of Policy Change

    Science.gov (United States)

    2009-01-01

    1 Major General Spurgeon Neel and the Army Physician Assistant: A Case Study of Policy Change Richard Glade ...a survey, which interestingly, made no attempt to study it. In 2005, Captain John Hughes surveyed every battalion and brigade commander at Fort

  2. Worry, General Self-Efficacy and School Achievement: An Exploratory Study with Chinese Adolescents

    Science.gov (United States)

    Tang, Natalia Yuen Yi; Westwood, Peter

    2007-01-01

    This study identified issues in school--and in life outside school--that caused significant worry for 120 Chinese adolescents (72 males, 48 females) attending a secondary school in Hong Kong. The study explored relationships existing among 3 variables comprising degree of worry, students' general self-efficacy, and their academic achievement.…

  3. A Longitudinal Twin Study of General Cognitive Ability over Four Decades

    Science.gov (United States)

    Lyons, Michael J.; Panizzon, Matthew S.; Liu, Weijian; McKenzie, Ruth; Bluestone, Noah J.; Grant, Michael D.; Franz, Carol E.; Vuoksimaa, Eero P.; Toomey, Rosemary; Jacobson, Kristen C.; Reynolds, Chandra A.; Kremen, William S.; Xian, Hong

    2017-01-01

    In this longitudinal study we examined the stability of general cognitive ability (GCA), as well as heterogeneity and genetic and environmental influences underlying individual differences in change. We investigated GCA from young adulthood through late midlife in 1,288 Vietnam Era Twin Study of Aging participants at ages ~20, ~56, and ~62 years.…

  4. The Benchmarking Capacity of a General Outcome Measure of Academic Language in Science and Social Studies

    Science.gov (United States)

    Mooney, Paul; Lastrapes, Renée E.

    2016-01-01

    The amount of research evaluating the technical merits of general outcome measures of science and social studies achievement is growing. This study targeted criterion validity for critical content monitoring. Questions addressed the concurrent criterion validity of alternate presentation formats of critical content monitoring and the measure's…

  5. Predictors of outcome in neck and shoulder symptoms: a cohort study in general practice

    NARCIS (Netherlands)

    Bot, S.D.M.; Waal, van der J.M.; Terwee, C.B.; Windt-Mens, van der D.A.W.M.; Scholten, R.J.P.M.; Bouter, L.M.; Dekker, J.

    2005-01-01

    STUDY DESIGN: An observational prospective cohort study in general practice. OBJECTIVES: To describe the clinical course and to identify predictors of recovery, changes in pain intensity, and changes in functional disability in patients with neck or shoulder symptoms at 3- and 12-month follow-up. SU

  6. A Study of EL2 Pilots' Radio Communication in the General Aviation Environment

    Science.gov (United States)

    Estival, Dominique; Molesworth, Brett

    2009-01-01

    This paper reports on the preliminary stages of a project designed to investigate communication problems in General Aviation and assess the utility of language technologies as a means of mitigation. The study presented in this paper is the first of a three-part study, in which we aim to investigate the extent to which the English language…

  7. Students' Misunderstandings about the Energy Conservation Principle: A General View to Studies in Literature

    Science.gov (United States)

    Tatar, Erdal; Oktay, Munir

    2007-01-01

    This paper serves to review previously reported studies on students' misunderstandings about the energy conservation principle (the first law of thermodynamics). Generally, studies in literature highlighted students' misunderstandings about the energy conservation principle stem from preliminaries about energy concept in daily life. Since prior…

  8. A Reliability Generalization Study of the Marlowe-Crowne Social Desirability Scale.

    Science.gov (United States)

    Beretvas, S, Natasha; Meyers, Jason L.; Leite, Walter L.

    2002-01-01

    Conducted a reliability generalization study of the Marlowe-Crowne Social Desirability Scale (D. Crowne and D. Marlowe, 1960). Analysis of 93 studies show that the predicted score reliability for male adolescents was 0.53, and reliability for men's responses was lower than for women's. Discusses the need for further analysis of the scale. (SLD)

  9. Barriers to the implementation of preconception care guidelines as perceived by general practitioners: a qualitative study

    Directory of Open Access Journals (Sweden)

    Mazza Danielle

    2013-01-01

    Full Text Available Abstract Background Despite strong evidence of the benefits of preconception interventions for improving pregnancy outcomes, the delivery and uptake of preconception care and periconceptional folate supplementation remain low. General practitioners play a central role in the delivery of preconception care. Understanding general practitioners’ perceptions of the barriers and enablers to implementing preconception care allows for more appropriate targeting of quality improvement interventions. Consequently, the aim of this study was to examine the barriers and enablers to the delivery and uptake of preconception care guidelines from general practitioners’ perspective using theoretical domains related to behaviour change. Methods We conducted a qualitative study using focus groups consisting of 22 general practitioners who were recruited from three regional general practice support organisations. Questions were based on the theoretical domain framework, which describes 12 domains related to behaviour change. General practitioners’ responses were classified into predefined themes using a deductive process of thematic analysis. Results Beliefs about capabilities, motivations and goals, environmental context and resources, and memory, attention and decision making were the key domains identified in the barrier analysis. Some of the perceived barriers identified by general practitioners were time constraints, the lack of women presenting at the preconception stage, the numerous competing preventive priorities within the general practice setting, issues relating to the cost of and access to preconception care, and the lack of resources for assisting in the delivery of preconception care guidelines. Perceived enablers identified by general practitioners included the availability of preconception care checklists and patient brochures, handouts, and waiting room posters outlining the benefits and availability of preconception care consultations

  10. General practitioners’ assessment practices of patients' need for lifestyle intervention. A vignette study on the impact of social distance on general practitioners’ patient assessments

    DEFF Research Database (Denmark)

    Ilsvard, Sofie

    2015-01-01

    In Denmark, as in other welfare countries, the general practitioner is the first point of contact in the health services, which stresses the general practitioners’ role as gatekeeper and mediator of the health services. General practitioners’ work is characterized by a relatively extensive...... discretion, especially in preventive contexts with no clear-cut guidelines. However, despite its potential influence, few studies have focused on whether social distance has an impact on general practitioners’ assessment practices of patients, which thus seems to be a blind spot in the literature. To study...... the mechanisms facilitating the process of social distance systematically, I apply the vignette method. Drawing on Bourdieu’s theoretical framework of social distance, I examine how general practitioners assess different socially positioned patients as needy for preventive lifestyle intervention. I expect social...

  11. Surgery or general medicine: a study of the reasons underlying the choice of medical specialty

    Directory of Open Access Journals (Sweden)

    Patrícia Lacerda Bellodi

    Full Text Available CONTEXT: The reality of medical services in Brazil points towards expansion and diversification of medical knowledge. However, there are few Brazilian studies on choosing a medical specialty. OBJECTIVE: To investigate and characterize the process of choosing the medical specialty among Brazilian resident doctors, with a comparison of the choice between general medicine and surgery. TYPE OF STUDY: Stratified survey. SETTING: Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo (HC-FMUSP. METHODS: A randomized sample of resident doctors in general medicine (30 and surgery (30 was interviewed. Data on sociodemographic characteristics and the moment, stability and reasons for the choice of specialty were obtained. RESULTS: The moment of choice between the two specialties differed. Surgeons (30% choose the specialty earlier, while general doctors decided progressively, mainly during the internship (43%. Most residents in both fields (73% general medicine, 70% surgery said they had considered another specialty before the current choice. The main reasons for general doctors' choice were contact with patients (50%, intellectual activities (30% and knowledge of the field (27%. For surgeons the main reasons were practical intervention (43%, manual activities (43% and the results obtained (40%. Personality was important in the choice for 20% of general doctors and for 27% of surgeons. DISCUSSION: The reasons found for the choice between general medicine and surgery were consistent with the literature. The concepts of wanting to be a general doctor or a surgeon are similar throughout the world. Personality characteristics were an important influencing factor for all residents, without statistical difference between the specialties, as was lifestyle. Remuneration did not appear as a determinant. CONCLUSION: The results from this group of Brazilian resident doctors corroborated data on choosing a medical specialty from other countries

  12. What is a 'learning organization' in general practice? A case study.

    Science.gov (United States)

    Cantle, F

    2000-08-01

    The focus of the research herein was to examine the main characteristics of a learning organization in a general practice. An ethnographic approach was taken. Blockage instrument, structured interviews and documentary evidence were used to establish the validity and the reliability of the research. Data were collected and analysed systematically. It is shown that the case study practice contains the characteristics of a learning organization and key management and organizational issues, such as policy making, practice management and performance management, are identified. Management strategies are offered and recommendations made both for the case study practice and generally for primary and secondary healthcare services. We hope that our research will guide further strategic planning in the case study practice, and that it will help other general practices and the NHS as a whole in the development of a learning organization.

  13. A comparison of gastroenteritis in a general practice-based study and a community-based study.

    NARCIS (Netherlands)

    Wit, M.A.S. de; Kortbeek, L.M.; Koopmans, M.P.G.; Jager, C.J. de; Wannet, W.J.B.; Bartelds, A.I.M.; Duynhoven, Y.T.H.P. van

    2001-01-01

    We compared gastroenteritis cases that consulted a general practitioner (GP) with those who did not in a community-based study and also with those in a GP-based study. We aimed to identify factors associated with consultation, and with inclusion of cases by GPs, and secondly to study the effects on

  14. A comparison of gastroenteritis in a general practice-based study and a community-based study.

    NARCIS (Netherlands)

    Wit, M.A.S. de; Kortbeek, L.M.; Koopmans, M.P.G.; Jager, C.J. de; Wannet, W.J.B.; Bartelds, A.I.M.; Duynhoven, Y.T.H.P. van

    2001-01-01

    We compared gastroenteritis cases that consulted a general practitioner (GP) with those who did not in a community-based study and also with those in a GP-based study. We aimed to identify factors associated with consultation, and with inclusion of cases by GPs, and secondly to study the effects on

  15. GENERAL GEOLOGY

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    <正>20110727 Dai Deqiu (Institute of Geology, Hunan University of Science and Technology, Xiangtan 411201, China); Wang Daode The Evolvement Models and Progress of Research on Formation of Ca-,Al-Rich inclusions in Chondrites (Geological Review, ISSN0371-5736, CN11-1952/P, 56(3), 2010, p.374-383, 2 illus., 1 table, 72 refs.)Key words: chondrites Ca-, Al-rich inclusions (CAIs) are the earliest assemblages formed in the solar nebula. The formation models of CAIs include gas-soild condensation, crystallization from melting or partial melting and high-temperature evaporating residues. The latest study shows similar distribution patterns of the petrographic types and sizes of CAIs in various chondrites. The petrographic characters argue that CAIs in various chemical groups of chondrites formed under similar processes and conditions probably in a same region in the solar nebula.

  16. General siting study 95. Siting of a deep repository for spent nuclear fuel

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-10-01

    General Siting Study 95 is a detailed description of the work carried out to put the siting of a deep repository in a national and regional context. The report is based on SKB`s siting factors, which have been applied on a national scale. Different factors of importance or of possible importance for the long-term radiological safety, technology, land and environment as well as society are described and evaluated. This report is the overall description on general siting studies which the government considered that SKB should report in connection with the RD and D Programme 95. 121 refs, 40 figs.

  17. Integrated logistic support studies using behavioral Monte Carlo simulation, supported by Generalized Stochastic Petri Nets

    Energy Technology Data Exchange (ETDEWEB)

    Garnier, Robert; Chevalier, Marcel [Schneider Electric (France)

    2000-07-01

    Studying large and complex industrial sites, requires more and more accuracy in modeling. In particular, when considering Spares, Maintenance and Repair / Replacement processes, determining optimal Integrated Logistic Support policies requires a high level modeling formalism, in order to make the model as close as possible to the real considered processes. Generally, numerical methods are used to process this kind of study. In this paper, we propose an alternate way to process optimal Integrated Logistic Support policy determination when dealing with large, complex and distributed multi-policies industrial sites. This method is based on the use of behavioral Monte Carlo simulation, supported by Generalized Stochastic Petri Nets. (author)

  18. General Health Status Among Students of Islamic Azad University: A Cross-Sectional Study from Iran

    Directory of Open Access Journals (Sweden)

    Mohammad Taghi Savadpour

    2015-06-01

    Full Text Available Background & Aims of the Study: Health is one of the basic needs of human. There is a close relationship between physical and mental health. Human psyche is directly affected by his physical condition, and mutually his body and actions of human systems are influenced by psychological and mental space. Students because of their particular circumstances are vulnerable to mental health problems. The purpose of this study is to determine the general health status of students of Islamic Azad University. Materials & Methods: This descriptive analytical research was conducted on 478 students of Khalkhal Islamic Azad University. Simple random sampling method was used. General health questionnaire (GHQ-28 was used as research tool. Following data collection, data were analyzed using SPSS Software 13. Results: The results show that mean score of general health of the subjects is higher than cutoff. In this study, 21.3 percent of students were suspected of impaired health. Also, status of general health of female students was worse than male students and significant statistical relationship was observed between general health status and all its sub-scales except depression and gender (P < 0.5. Conclusions: G eneral health of students especially female students is impaired which may considerably affect their learning and performance and academic achievement.

  19. A COMPARATIVE STUDY OF EPIDURAL VS. GENERAL ANAESTHESIA FOR LAPAROSCOPIC CHOLECYSTECTOMY

    Directory of Open Access Journals (Sweden)

    Jayadheer D

    2016-07-01

    Full Text Available BACKGROUND Laparoscopic cholecystectomy has many benefits for patients including reduced postoperative pain, postoperative stay, and fewer wound-related complications. Specifically, obese patients and patients with severe respiratory diseases are benefited with laparoscopic procedures. The procedure is normally performed under general anaesthesia. But off late, this procedure was tried under regional successfully especially under epidural anaesthesia. Various reports in the literature suggest the safety of the use of spinal, epidural, and combined spinal-epidural anaesthesia in laparoscopic procedures. The advantages of regional anaesthesia include: Prevention of airway manipulation, an awake and spontaneously breathing patient intraoperatively, minimal nausea and vomiting, effective postoperative analgesia, and early ambulation and recovery. However, regional anaesthesia maybe associated with a few side effects such as the requirement of a higher sensory level, more severe hypotension, shoulder discomfort due to diaphragmatic irritation, and respiratory embarrassment caused by pneumoperitoneum. Further studies maybe required to establish the advantage of regional anaesthesia over general anaesthesia for its eventual global use in different patient populations. METHODS 40 patients with the ASA (American Society of Anaesthesiologists class I and II were enrolled after taking prior written consent for laparoscopic cholecystectomy at King George Hospital, Visakhapatnam. These 40 patients were divided into two groups of equal size and randomised using random numbers. One group was given general anaesthesia and in the other group procedures were performed under epidural anaesthesia. Two patients in the epidural group required general anaesthesia. RESULTS 40 patients were divided and studied of which the results proved that general anaesthesia was better over epidural anaesthesia except for the disadvantages namely cost factor, PONV, and high risk of

  20. Comparison of dark energy models: A perspective from the latest observational data

    CERN Document Server

    Li, Miao; Zhang, Xin

    2009-01-01

    In this paper, we compare some popular dark energy models with the assumption of a flat universe by using the latest observational data including the type Ia supernovae Constitution compilation, the baryon acoustic oscillation measurement from the Sloan Digital Sky Survey and the Two Degree Field Galaxy Redshift Survey, and the cosmic microwave background measurement given by the five-year Wilkinson Microwave Anisotropy Probe observations. Model comparison statistics such as the Bayesian and Akaike information criteria are applied to assess the worth of the models. These statistics favor models that give a good fit with fewer parameters. Based on this analysis, we find that the simplest cosmological constant model that has only one free parameter is still preferred by the current data. For other dynamical dark energy models, we find that some of them, such as the $\\alpha$ dark energy, constant $w$, generalized Chaplygin gas, and holographic dark energy models, can provide good fits to the current data, and th...

  1. Organizational values in general practice and public involvement: case studies in an urban district.

    Science.gov (United States)

    Brown, I

    2001-05-01

    A multiple case study design was used to explore dimensions of organizational values in general practice with respect to developing public involvement. The study was undertaken in an urban district in England with data collected through in-depth individual and focus group interviews with service providers and service users. Four general practice organizations were randomly selected for study after sorting all in the district according to their record of developing involvement activities. The case studies provide evidence of how organizational values can differ markedly in general practice in relation to ideas of public involvement, with consequences for the quantity and quality of activities for involving local people and service users. The differences manifest themselves in the beliefs and attitudes of service providers about the purpose of the organization and the types of relationships that are appropriate with service users and local people. Service users appear to be very perceptive to the underlying ethos and purpose to their practice organization and this affects their responsiveness to initiatives for their involvement. The dimensions of the different values found in the study appear to be essentially the same as a number of established empirical findings of variations in values in general practice: an orientation to a narrow medical role and to general practice as a business are associated with a low valuation of involvement; an orientation to teamwork and to a broader social role appear more congruent with the development of involvement. Power is a critical issue in this setting with evidence in the study of the dominance of the medical practitioners in establishing organizational values and the nature of public involvement activities.

  2. 41 CFR 60-3.5 - General standards for validity studies.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 1 2010-07-01 2010-07-01 true General standards for validity studies. 60-3.5 Section 60-3.5 Public Contracts and Property Management Other Provisions Relating to Public Contracts OFFICE OF FEDERAL CONTRACT COMPLIANCE PROGRAMS, EQUAL EMPLOYMENT...

  3. Incorporating AAC and General Instructional Strategies in Requesting Interventions: A Case Study in Down Syndrome

    Science.gov (United States)

    Lanter, Elizabeth; Russell, Sharon D.; Kuriakose, Annu; Blevins, Kasey E.

    2016-01-01

    This article provides clinicians and educators a useful conceptualization of general instructional strategies often used to promote the performance of requests in children with developmental disabilities, and which can be applied in interventions that utilize augmentative and alternative communication. A case study illustrates the specialized…

  4. Patient demands, lack of reciprocity, and burnout: a five-year longitudinal study about general practitioners.

    NARCIS (Netherlands)

    Bakker, A.B.; Schaufeli, W.B.; Sixma, H.J.; Bosveld, W.; Dierendonck, D. van

    2000-01-01

    This study among a sample of 207 general practitioners (GPs) uses a five-year longitudinal design to test a process model of burnout. On the basis of social exchange and equity theory, it is hypothesized and found that demanding patient contacts produce a lack of reciprocity in the GP-patient

  5. Care complexity in the general hospital - Results from a European study

    NARCIS (Netherlands)

    de Jonge, P; Huyse, FJ; Slaets, JPJ; Herzog, T; Lobo, A; Lyons, JS; Opmeer, BC; Stein, B; Arolt, [No Value; Balogh, N; Cardoso, G; Fink, P; Rigatelli, M; van Dijck, R; Mellenbergh, GJ

    2001-01-01

    There is increasing pressure to effectively treat patients with complex care needs from the moment of admission to the general hospital. In this study, the authors developed a measurement strategy for hospital-based care complexity. The authors' four-factor model describes the interrelations between

  6. Prevalence of heart failure and left ventricular dysfunction in the general population; The Rotterdam Study

    NARCIS (Netherlands)

    A. Mosterd (Arend); A.W. Hoes (Arno); M.C. de Bruyne (Martine); D.T. Linker (David); D.E. Grobbee (Diederick); J.W. Deckers (Jaap); A. Hofman (Albert)

    1999-01-01

    textabstractAIMS: To determine the prevalence of heart failure and symptomatic as well as asymptomatic left ventricular systolic dysfunction in the general population. METHODS AND RESULTS: In 5540 participants of the Rotterdam Study (age 68.9+/-8.7 years, 2251 men) aged

  7. Energy conservation: Policies, programs, and general studies. Citations from the NTIS data base

    Science.gov (United States)

    Hundemann, A. S.

    1980-08-01

    National policies, programs, and general studies or ways to conserve energy are presented. Topic areas cover such subjects as electric load management, effects of price and taxation on energy conservation, public attitudes and behavior toward energy saving, energy savings through reduction in hot water consumption, and telecommunications substitutability for travel.

  8. Attachment in the doctor-patient relationship in general practice: a qualitative study

    DEFF Research Database (Denmark)

    Frederiksen, Heidi Bøgelund; Kragstrup, Jakob; Dehlholm-Lambertsen, Birgitte

    2010-01-01

    OBJECTIVE: To explore why interpersonal continuity with a regular doctor is valuable to patients. DESIGN, SETTING, AND SUBJECTS: A qualitative study based on 22 interviews with patients, 12 who saw their regular general practitioner (GP) and 10 who saw an unfamiliar GP. The patients were selected...

  9. Rhinosinusitis in morbidity registrations in Dutch General Practice: a retro-spective case-control study

    NARCIS (Netherlands)

    Hoffmans, R.; Schermer, T.R.; Linde, K. van der; Bor, H.; Boven, K. van; Weel, C. van; Fokkens, W.

    2015-01-01

    BACKGROUND: There is only limited accurate data on the epidemiology of rhinosinusitis in primary care. This study was conducted to assess the incidence of acute and chronic rhinosinusitis by analysing data from two Dutch general practice registration projects. Several patient characteristics and dis

  10. Research data supporting "Crowdsourcing the General Public for Large Scale Molecular Pathology Studies in Cancer"

    OpenAIRE

    2015-01-01

    Complete data set for the manuscript "Crowdsourcing the general public for large scale molecular pathology studies in cancer". Published at: http://dx.doi.org/10.1016/j.ebiom.2015.05.009 This work was supported by the Cancer Research UK [C490/A10124, C490/A16561

  11. Comparative Study of Bullying Victimization among Students in General and Special Education

    Science.gov (United States)

    Hartley, Michael T.; Bauman, Sheri; Nixon, Charisse L.; Davis, Stan

    2015-01-01

    Research on bullying is an important avenue for understanding the social integration of students in special education. Focused on 3,305 students who self-reported victimization of two to three times per month or more, this study compared the pattern of verbal, relational, and physical bullying among students in general education and special…

  12. Systematic review of general burden of disease studies using disability-adjusted life years

    NARCIS (Netherlands)

    S. Polinder (Suzanne); J.A. Haagsma (Juanita); C. Stein (Claudia); A.H. Havelaar (Arie)

    2012-01-01

    textabstractObjective: To systematically review the methodology of general burden of disease studies. Three key questions were addressed: 1) what was the quality of the data, 2) which methodological choices were made to calculate disability adjusted life years (DALYs), and 3) were uncertainty and ri

  13. Can They Succeed? Exploring At-Risk Students' Study Habits in College General Chemistry

    Science.gov (United States)

    Ye, Li; Shuniak, Constantine; Oueini, Razanne; Robert, Jenay; Lewis, Scott

    2016-01-01

    A well-established literature base identifies a portion of students enrolled in post-secondary General Chemistry as at-risk of failing the course based on incoming metrics. Learning about the experiences and factors that lead to this higher failure rate is essential toward improving retention in this course. This study examines the relationship…

  14. Learning and Studying Strategies Used by General Chemistry Students with Different Affective Characteristics

    Science.gov (United States)

    Chan, Julia Y. K.; Bauer, Christopher F.

    2016-01-01

    Students in general chemistry were partitioned into three groups by cluster analysis of six affective characteristics (emotional satisfaction, intellectual accessibility, chemistry self-concept, math self-concept, self-efficacy, and test anxiety). The at-home study strategies for exam preparation and in-class learning strategies differed among the…

  15. Moving to paperlessness: a case study from a large general practice

    Directory of Open Access Journals (Sweden)

    Stephen Carr-Bains

    2003-11-01

    The implications of this case study are that a committed general practice can achieve a largely paperless environment in approximately two years. The practice is now fit to be part of any move towards integration of records within its local health community, and can demonstrate from its computer records that it meets the quality targets for primary care.

  16. Does Empathy Predict Instructional Assignment-Related Stress? A Study in Special and General Education Teachers

    Science.gov (United States)

    Platsidou, Maria; Agaliotis, Ioannis

    2017-01-01

    The role of empathy in the teaching profession has been vastly investigated in relation to its effect on students, but research on how teachers' empathy affects their own well-being at work is limited. This study investigated empathy and instructional assignment-related stress factors of primary school teachers serving in general or special…

  17. Generalization in Qualitative IS Research - Approaches and their Application to a Case Study on SOA Development

    Directory of Open Access Journals (Sweden)

    Matthias Goeken

    2012-04-01

    Full Text Available In qualitative information systems research little methodological support has been provided so far for the generalization of data. Generalizability, however, is a major concern in this field. It has been subject to a number of publications in recent years but commonly accepted frameworks of generalizability and methodological guidance are still missing. In order to address these problems, this paper investigates if and how abstraction mechanisms from the field of conceptual modeling can be used to generalize empirical data. An explorative single case study on the development of service-oriented architectures provides the raw data for an exemplary application. Abstraction mechanisms are used to generalize observations from the case study and to transform them into hypotheses. Finally, another abstraction leads to three models illustrating relationships of certain concepts and abstract categories as a major result of this case study. The paper shows that abstraction mechanisms from the field of conceptual modeling can be used for the generalization of case study data and provides guidance on how to use these mechanisms.

  18. Prognosis and vascular co-morbidity in dementia a historical cohort study in general practice.

    NARCIS (Netherlands)

    Meerman, L.; Lisdonk, E.H. van de; Koopmans, R.T.C.M.; Zielhuis, G.A.; Olde Rikkert, M.G.M.

    2008-01-01

    BACKGROUND: Disease management of dementia in general practice (GP) is hampered by a lack of data on the prognosis of dementia. AIM: To gain more insight into the life expectancy of and the effects of cardiovascular and cerebrovascular co-morbidity in dementia patients in GP. DESIGN OF STUDY: Histor

  19. Behavioral outcomes of picky eating in childhood : a prospective study in the general population

    NARCIS (Netherlands)

    Cano, Sebastian Cardona; Hoek, Hans W.; van Hoeken, Daphne; de Barse, Lisanne M.; Jaddoe, Vincent W. V.; Verhulst, Frank C.; Tiemeier, Henning

    2016-01-01

    BackgroundPicky eaters in the general population form a heterogeneous group. It is important to differentiate between children with transient picky eating (PE) and persistent PE behavior when adverse outcomes are studied. We analyzed four PE trajectories to determine the associations with child ment

  20. A Case Study of the Flipped Classroom in a Korean University General English Course

    Science.gov (United States)

    Choe, Erika; Seong, Myeong-Hee

    2016-01-01

    Research has proven the effectiveness of Flipped Classrooms (FC) for a variety of settings. However, more exploration needs to be done in regards to how FC can be used effectively in foreign language classrooms. The purpose of this study was to 1) explore student perceptions of FC in a Korean university general English course and 2) provide…

  1. Vaginal symptoms of unknown etiology - a study in dutch general-practice

    NARCIS (Netherlands)

    Dekker, Janny H.; Boeke, A. Joan P.; Janssens, J; van Eijk, J.Th.M.

    1993-01-01

    Vaginal symptoms are frequently presented by women to general practitioners. In many cases, the aetiology of these symptoms remains unknown. This study focused on the factors associated with microbiologically unexplained vaginal symptoms, the course of symptoms and signs in these cases, and factors

  2. Nonallergic rhinitis and its association with smoking and lower airway disease: A general population study

    DEFF Research Database (Denmark)

    Håkansson, Kåre; von Buchwald, Christian; Thomsen, Simon F;

    2011-01-01

    The cause of nonallergic rhinitis (NAR) and its relation to lower airway disease remains unclear. The purpose of this study was to perform a descriptive analysis of the occurrence of rhinitis in a Danish general population with focus on NAR and its association with smoking and lower airway disease....

  3. Does Empathy Predict Instructional Assignment-Related Stress? A Study in Special and General Education Teachers

    Science.gov (United States)

    Platsidou, Maria; Agaliotis, Ioannis

    2017-01-01

    The role of empathy in the teaching profession has been vastly investigated in relation to its effect on students, but research on how teachers' empathy affects their own well-being at work is limited. This study investigated empathy and instructional assignment-related stress factors of primary school teachers serving in general or special…

  4. Diagnosis and interpretation of injuries: a study of Dutch general practitioners

    NARCIS (Netherlands)

    Reijnders, U.J.L.; Baasbank, van M.C.; Wal, van der G.

    2005-01-01

    This study explores the ability of Dutch general practitioners (GPs) in recognising types of injury. In the three sample cases, 48-91% classified the injury correctly. Only 9% of GPs recognised self-harm injury and in the 3rd case (child abuse) only 15% referred to the improbability of the account g

  5. A systematic study of finite BRST-BFV transformations in generalized Hamiltonian formalism

    Science.gov (United States)

    Batalin, Igor A.; Lavrov, Peter M.; Tyutin, Igor V.

    2014-09-01

    We study systematically finite BRST-BFV transformations in the generalized Hamiltonian formalism. We present explicitly their Jacobians and the form of a solution to the compensation equation determining the functional field dependence of finite Fermionic parameters, necessary to generate an arbitrary finite change of gauge-fixing functions in the path integral.

  6. A systematic study of finite BRST-BFV transformations in generalized Hamiltonian formalism

    CERN Document Server

    Batalin, Igor A; Tyutin, Igor V

    2014-01-01

    We study systematically finite BRST-BFV transformations in the generalized Hamiltonian formalism. We present explicitly their Jacobians and the form of a solution to the compensation equation determining the functional field dependence of finite Fermionic parameters, necessary to generate arbitrary finite change of gauge-fixing functions in the path integral.

  7. A systematic study of finite BRST-BFV transformations in $Sp(2)$-extended generalized Hamiltonian formalism

    CERN Document Server

    Batalin, Igor A; Tyutin, Igor V

    2014-01-01

    We study systematically finite BRST-BFV transformations in $Sp(2)$-extended generalized Hamiltonian formalism. We present explicitly their Jacobians and the form of a solution to the compensation equation determining the functional field dependence of finite Fermionic parameters, necessary to generate arbitrary finite change of gauge-fixing functions in the path integral.

  8. A systematic study of finite BRST-BFV transformations in Sp(2)-extended generalized Hamiltonian formalism

    Science.gov (United States)

    Batalin, Igor A.; Lavrov, Peter M.; Tyutin, Igor V.

    2014-09-01

    We study systematically finite BRST-BFV transformations in Sp(2)-extended generalized Hamiltonian formalism. We present explicitly their Jacobians and the form of a solution to the compensation equation determining the functional field dependence of finite Fermionic parameters, necessary to generate arbitrary finite change of gauge-fixing functions in the path integral.

  9. General practitioners' continuing medical education: A prospective study from the County of Aarhus

    DEFF Research Database (Denmark)

    Nielsen, Jan E.; Lous, Jørgen; Adeler, H.F.;

    2002-01-01

    Participation of Danish general practitioners (GPs) in continuing medical education (CME) has often been the subject of debate, although very little is known about the extent and content of activities. One-hundred-and-sixty-one Danish GPs participated in this one-year prospective study...

  10. Vaginal symptoms of unknown etiology - a study in dutch general-practice

    NARCIS (Netherlands)

    Dekker, Janny H.; Boeke, A. Joan P.; Janssens, J; van Eijk, J.Th.M.

    Vaginal symptoms are frequently presented by women to general practitioners. In many cases, the aetiology of these symptoms remains unknown. This study focused on the factors associated with microbiologically unexplained vaginal symptoms, the course of symptoms and signs in these cases, and factors

  11. Generalized canonical correlation analysis of matrices with missing rows : A simulation study

    NARCIS (Netherlands)

    van de Velden, Michel; Bijmolt, Tammo H. A.

    2006-01-01

    A method is presented for generalized canonical correlation analysis of two or more matrices with missing rows. The method is a combination of Carroll's (1968) method and the missing data approach of the OVERALS technique (Van der Burg, 1988). In a simulation study we assess the performance of the m

  12. Can They Succeed? Exploring At-Risk Students' Study Habits in College General Chemistry

    Science.gov (United States)

    Ye, Li; Shuniak, Constantine; Oueini, Razanne; Robert, Jenay; Lewis, Scott

    2016-01-01

    A well-established literature base identifies a portion of students enrolled in post-secondary General Chemistry as at-risk of failing the course based on incoming metrics. Learning about the experiences and factors that lead to this higher failure rate is essential toward improving retention in this course. This study examines the relationship…

  13. Learning and Studying Strategies Used by General Chemistry Students with Different Affective Characteristics

    Science.gov (United States)

    Chan, Julia Y. K.; Bauer, Christopher F.

    2016-01-01

    Students in general chemistry were partitioned into three groups by cluster analysis of six affective characteristics (emotional satisfaction, intellectual accessibility, chemistry self-concept, math self-concept, self-efficacy, and test anxiety). The at-home study strategies for exam preparation and in-class learning strategies differed among the…

  14. Patient demands, lack of reciprocity, and burnout: a five-year longitudinal study about general practitioners.

    NARCIS (Netherlands)

    Bakker, A.B.; Schaufeli, W.B.; Sixma, H.J.; Bosveld, W.; Dierendonck, D. van

    2000-01-01

    This study among a sample of 207 general practitioners (GPs) uses a five-year longitudinal design to test a process model of burnout. On the basis of social exchange and equity theory, it is hypothesized and found that demanding patient contacts produce a lack of reciprocity in the GP-patient rel

  15. Individualizing Elementary General Music Instruction: Case Studies of Assessment and Differentiation

    Science.gov (United States)

    Salvador, Karen

    2011-01-01

    Elementary general music teachers typically teach hundreds of students every week. Each child has individual learning needs due to a variety of factors, such as prior experiences with music, music aptitude, learning style, and personality. The purpose of this qualitative study was to explore ways that experienced teachers used assessments to…

  16. Behavioral outcomes of picky eating in childhood: A prospective study in the general population

    NARCIS (Netherlands)

    S. Cardona Cano; H.W. Hoek (Hans); D. Van Hoeken (Daphne); L.M. de Barse (Lisanne); V.W.V. Jaddoe (Vincent); F.C. Verhulst (Frank); H.W. Tiemeier (Henning)

    2016-01-01

    markdownabstract__Background:__ Picky eaters in the general population form a heterogeneous group. It is important to differentiate between children with transient picky eating (PE) and persistent PE behavior when adverse outcomes are studied. We analyzed four PE trajectories to determine the associ

  17. General Education in Health Science-Focused Institutions: An Explanatory Mixed Methods Study

    Science.gov (United States)

    Rosario, Peggy

    2012-01-01

    The purpose of this study was to describe the structure of general education curricula at baccalaureate colleges of health science in relationship to Bergquist's Career-Based Model of curriculum. Using an explanatory sequential mixed methods approach, the model was tested by examining whether the curricula were both prescriptive and specific.…

  18. Acceptance of online audio-visual cultural heritage archive services: a study of the general public

    NARCIS (Netherlands)

    Ongena, G.; Wijngaert, van de L.A.L.; Huizer, E.

    2013-01-01

    Introduction. This study examines the antecedents of user acceptance of an audio-visual heritage archive for a wider audience (i.e., the general public) by extending the technology acceptance model with the concepts of perceived enjoyment, nostalgia proneness and personal innovativeness. Method. A W

  19. HISTORIOGRAPHY GENERAL, REGIONAL AND SPECIAL STUDIES OF JUDICIAL REFORM IN RUSSIA 1864

    Directory of Open Access Journals (Sweden)

    Sergei Evgenievich Strakhov

    2014-10-01

    Full Text Available In today's world, a crucial role is played by the judiciary. In the period lasting judicial reform, it is important to explore this institution not only at the present stage, but also to trace the history of its development, including - through analysis and synthesis of existing studies of the judiciary and judicial reforms.The purpose of this study - to explore the historiography of general, special and regional studies of judicial reform of1864 inRussia, to classify research on history and on the subject of the study.Scientific, theoretical and practical significance of the work lies in the fact that the study of this topic will summarize the significant weight of the studies of the judicial reform of 1864 and classified by facilitating orientation interested in individuals in the study subjects.The author uses historical, comparative, hermeneutical, mathematical methods, as well as general methods of scientific research.The author analyzes the historiography of general, special and regional studies of the judicial reform of1864 inRussia, introducing a classification of such studies in chronological order (pre-revolutionary, Soviet and modern stages and subject matter (common - affecting all aspects of judicial reform, special - dedicated to a particular aspect (legal agencies, prosecutors, legal, etc. and regional - dedicated to judicial reform, or some aspects of it in some regions of Russia.The results of this study are scientific and practical value, because they can be useful for teaching students - in industry disciplines "judiciary", "advocacy", "notary public", "public prosecutor's supervision" and general theoretical "History of State and Law," "History of the fatherland" ; in science - by picking up information about the historiography of the judicial reform, and in practice - said work can serve as a guide to research judicial reform, which may be useful to practitioners of judicial and investigative bodies, as well as - prosecutors

  20. The vehicle routing problem latest advances and new challenges

    CERN Document Server

    Golden, Bruce L; Wasil, Edward A

    2008-01-01

    The Vehicle Routing Problem (VRP) has been an especially active and fertile area of research. Over the past five to seven years, there have been numerous technological advances and exciting challenges that are of considerable interest to students, teachers, and researchers. The Vehicle Routing Problem: Latest Advances and New Challenges will focus on a host of significant technical advances that have evolved over the past few years for modeling and solving vehicle routing problems and variants. New approaches for solving VRPs have been developed from important methodological advances. These developments have resulted in faster solution algorithms, more accurate techniques, and an improvement in the ability to solve large-scale, complex problems. The book will systematically examine these recent developments in the VRP and provide the following in a unified and carefully developed presentation: Present novel problems that have arisen in the vehicle routing domain and highlight new challenges for the field; Pre...

  1. The neutron decay spectrometer aSPECT: latest results

    Energy Technology Data Exchange (ETDEWEB)

    Borg, M.; Guardia, F.A.; Baessler, S.; Brito, L.C.; Glueck, F.; Heil, W.; Konrad, G.; Brito, L.C.; Horta, R.M.; Palmer, C.A.; Sobolev, Y. [Inst. fuer Physik, Univ. Mainz (Germany); Angerer, H.; Konorov, I.; Petzoldt, G.; Simson, M.; Wirth, H.F.; Zimmer, O. [Physik Dept. E18, TU Muenchen (Germany); Eberhardt, K. [Inst. fuer Kernchemie, Univ. Mainz (Germany); Rich, D. [FRM-II, TU Muenchen (Germany)

    2007-07-01

    The intention of the neutron decay spectrometer aSPECT is the measurement of the proton spectrum in the decay of free neutrons. The proton spectrum is used to deduce the value of the neutrino electron correlation coefficient a, an important experimental quantity which is useful to resolve the problem with the unitarity of the Cabbibo-Kobayashi-Maskawa Matrix. In a beam time in 2005/ 2006 at the neutron beam MEPHISTO of the research reactor ''Forschungsneutronenquelle Heinz Maier-Leibnitz'' (FRM-II), first proton spectra have been measured and several systematic tests were performed. In my talk, I will present the physical motivation and the design of our spectrometer, but mainly I will discuss our latest results and the on-going optimizations for the next beam time. (orig.)

  2. The status and latest issues on KAERI export control implementation

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Hyun Sook; Park, Ho Jun; Kim, Hyun Jo; Ko, Han Suk; Lee, Byung Doo [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2010-10-15

    There are four informal non-proliferation arrangements which seek to control the proliferation of weapons of mass destruction and their missile delivery systems and the transfer of conventional weapons and dual-use technologies. The four arrangements are Wassenaar Arrangement (WA) on export controls for conventional arms and dual use goods and technologies, Nuclear Supplies Group(NSG), Missile Technology Control Regime(MTCR) and Australia Group(AG) on chemical and biological weapons materials. ROK participates in four arrangements to seek to encourage responsible practice in the trade of strategic goods and technologies. It is achieved through the implementation of export control list. MKE Notification (Ministry of Knowledge Economy Notification No. 2009-250) specifies those items and technologies subject to control. In this paper, the status and latest issues on KAERI export control implementation are described

  3. Teachers' views of a new general education program in Hong Kong: a qualitative study.

    Science.gov (United States)

    Shek, Daniel T L; Yu, Lu; Wu, Florence K Y; Chai, Wen Y

    2017-02-01

    Under the new education reform in Hong Kong, The Hong Kong Polytechnic University (PolyU) has expanded its undergraduate education from 3 to 4 years since the 2012-2013 academic year. Along with the transition, the General University Requirements (GUR) has been developed as an integral part on general education of the new 4-year undergraduate curriculum of PolyU. The present study examined the implementation quality and effectiveness of the GUR in the 2012-2013 academic year based on focus group interviews with teachers. Twenty teachers who taught GUR subjects were interviewed for their perceptions and experiences about the GUR. Results revealed that the teachers generally had positive perceptions of the GUR in terms of its rationales, teaching and learning modes, and implementation quality. GUR subjects were also considered effective in helping students to develop in a holistic manner. The findings suggest that the first-year implementation of the GUR at PolyU was basically successful.

  4. Latest Jurassic-early Cretaceous regressive facies, northeast Africa craton

    Energy Technology Data Exchange (ETDEWEB)

    van Houten, F.B.

    1980-06-01

    Nonmarine to paralic detrital deposits accumulated in six large basins between Algeria and the Arabo-Nubian shield during major regression in latest Jurassic and Early Cretaceous time. The Ghadames Sirte (north-central Libya), and Northern (Egypt) basins lay along the cratonic margin of northeastern Africa. The Murzuk, Kufra, and Southern (Egypt) basins lay in the south within the craton. Data for reconstructing distribution, facies, and thickness of relevant sequences are adequate for the three northern basins only. High detrital influx near the end of Jurassic time and in mid-Cretaceous time produced regressive nubian facies composed largely of low-sinuosity stream and fahdelta deposits. In the west and southwest the Ghadames, Murzuk, and Kufra basins were filled with a few hundred meters of detritus after long-continued earlier Mesozoic aggradation. In northern Egypt the regressive sequence succeeded earlier Mesozoic marine sedimentation; in the Sirte and Southern basins correlative deposits accumulated on Precambrian and Variscan terranes after earlier Mesozoic uplift and erosion. Waning of detrital influx into southern Tunisia and adjacent Libya in the west and into Israel in the east initiated an Albian to early Cenomanian transgression of Tethys. By late Cenomanian time it had flooded the entire cratonic margin, and spread southward into the Murzuk and Southern basins, as well as onto the Arabo-Nubian shield. Latest Jurassic-earliest Cretaceous, mid-Cretaceous, and Late Cretaceous transgressions across northeastern Africa recorded in these sequences may reflect worldwide eustatic sea-level rises. In contrast, renewed large supply of detritus during each regression and a comparable subsidence history of intracratonic and marginal basins imply regional tectonic control. 6 figures.

  5. A prospective study of awareness and recall associated with general anaesthesia for caesarean section.

    Science.gov (United States)

    Paech, M J; Scott, K L; Clavisi, O; Chua, S; McDonnell, N

    2008-10-01

    The obstetric population is considered at high risk of awareness and recall when undergoing general anaesthesia for caesarean section. In recent years the incidence may have been altered by developments in obstetric anaesthesia. A prospective observational study of general anaesthesia for caesarean section was conducted during 2005 and 2006 in 13 maternity hospitals dealing with approximately 49,500 deliveries per annum in Australia and New Zealand. As a component of this study the frequency of recall of intraoperative events was examined using a structured postoperative interview on two occasions. There were 1095 general anaesthetics surveyed with 47% being performed for urgent fetal delivery. Thiopental was the most common induction agent (83%) with sevoflurane being used for maintenance in 63%. In 32% of cases a depth-of-anaesthesia monitor was used. In 763 cases (70%) there was least one postoperative interview enquiring into dreaming and awareness. There were two cases deemed to be consistent with awareness (incidence 0.26%, CI 0.03-0.9%, or 1 in 382) and three cases of possible awareness. Awareness with recall of intraoperative events remains a significant complication of obstetric general anaesthesia but was potentially avoidable in all cases detected in this study.

  6. The effect of domain-general inhibition-related training on language switching: An ERP study.

    Science.gov (United States)

    Liu, Huanhuan; Liang, Lijuan; Dunlap, Susan; Fan, Ning; Chen, Baoguo

    2016-01-01

    Previous studies have demonstrated that inhibitory control ability could be improved by training, and the Inhibitory Control (IC) Model implies that enhanced domain-general inhibition may elicit certain changes in language switch costs. In the present study, we aimed to examine the effects of domain-general inhibition training on performance in a language switching task, including which phase of domain-general inhibitory control benefits from training during an overt picture naming task in L1 and L2, using the event-related brain potentials (ERPs). Results showed that the language switch costs of bilinguals with high inhibitory control (high-IC) were symmetrical in both pretest and posttest, and those of bilinguals with low inhibitory control (low-IC) were asymmetrical in the pretest, but symmetrical in the posttest. Moreover, the high-IC group showed a larger LPC (late positive component) for L2 switch trials than for L1 trials in both pretest and posttest. In contrast, the low-IC group only exhibited a similar pattern of LPC in the posttest, but not in the pretest. These results indicate that inhibition training could increase the efficiency of language switching, and inhibitory control may play a key role during the lexical selection response phase. Overall, the present study is the first one to provide electrophysiological evidence for individual differences in the domain-general inhibition impact on language switching performance in low-proficient bilinguals. Copyright © 2015 Elsevier B.V. All rights reserved.

  7. Patients' experiences and expectations of general practice: a questionnaire study of differences by ethnic group

    Science.gov (United States)

    Ogden, Jane; Jain, Asha

    2005-01-01

    Background Research has highlighted variations in morbidity, mortality and health needs by ethnic group, and suggests that some ethnic groups may receive a poorer service. Aim To explore the impact of ethnic group on patients' experiences and expectations of their general practice consultation. Design of study Cross-sectional survey. Setting One general practice in a multicultural area of London. Method A total of 604 consecutive patients attending their general practice (response rate = 60.4%) who described their ethnic group as white British, black African, black African Caribbean or Vietnamese completed a measure relating to their experiences and their expectations of the general practice consultation in terms of treatment, communication, patients' agenda, patients' choice and doctor consistency. Results No differences were found for the black African or black African Caribbean patients. The Vietnamese patients reported better experiences of communication, more focus on their agenda and more attention to their choices than the white British patients. However, they also reported expecting lower levels of communication, less focus on their own agenda and reported wanting less GP consistency than the other ethnic groups. Conclusion Vietnamese patients state that they are receiving better standards of care in general practice than other ethnic groups. However, they also state that they expect less. This may illustrate a problem with assessing experiences of primary care. Higher scores of experience may not illustrate better consultations as such, but only better when compared with a lower level of initial expectation. A lower expectation is easier to fulfil. PMID:15904553

  8. Social class in childhood and general health in adulthood: questionnaire study of contribution of psychological attributes

    OpenAIRE

    Bosma, Hans; Mheen, Dike; Mackenbach, Johan

    1999-01-01

    textabstractOBJECTIVE: To determine the contribution of psychological attributes (personality characteristics and coping styles) to the association between social class in childhood and adult health among men and women. DESIGN: Partly retrospective, partly cross sectional study conducted in the framework of the Dutch GLOBE study. SUBJECTS: Sample of general population from south east Netherlands consisting of 2174 men and women aged 25-74 years. Baseline self reported data from 1991 provided ...

  9. Metabolic correlates of general cognitive function in nondemented elderly subjects: an FDG PET study

    Energy Technology Data Exchange (ETDEWEB)

    Cho, Sang Soo; Kwak, Young Bin; Lee, Eun Ju; Ryu, Chang Hyung; Chey, Jean Yung; Kim, Sang Eun [Seoul National University College of Medicine, Seoul (Korea, Republic of)

    2004-07-01

    While many studies examined the neural correlates of individual cognitive functions, few made efforts to identify the neural networks associated with general cognitive function. General cognitive function decline in the elderly population is not infrequent. This study examined the brain areas associated with general cognitive function in the elderly subjects. Community-dwelling 116 elderly subjects without dementing illnesses (age, 71{+-}5 y; 13 males and 103 females) participated. General cognitive ability was assessed with the Dementia Rating Scale (K-DRS), which is composed of five subtests of attention, initiation and perseveration, construction, conceptualization, and memory. The EVLT (Elderly Verbal Learning Test), a nine-word list learning test, was used for general memory assessment. Brain FDG PET scans were acquired in all subjects. Brain regions where metabolic levels are correlated with the total scores of K-DRS and EVLT were examined using SPM99. There was a significant positive correlation (P < 0.01 uncorrected, k=100) between the total score of K-DRS and glucose metabolism in the bilateral posterior cingulate gyri, bilateral inferior frontal gyri, left caudate, left inferior parietal lobule, right precuneus, bilateral unci, right parahippocampal gyrus, and right anterior cingulate gyrus. A significant positive correlation between the total score of EVLT and glucose metabolism was shown in the right precuneus, right posterior cingulate gyrus, left insula, bilateral inferior parietal lobules, left anterior cingulate gyrus, left caudate, right inferior frontal gyrus (P < 0.01 uncorrected, k=100). Our data showed the brain regions that are associated with general cognitive function in the elderly. Those regions may serve as the neural substrated of cognitive dysfunction associated with neurodegenerative and cerebrovascular diseases in elderly subjects.

  10. Air Pollution and Neuropsychological Development: A Review of the Latest Evidence.

    Science.gov (United States)

    Suades-González, Elisabet; Gascon, Mireia; Guxens, Mònica; Sunyer, Jordi

    2015-10-01

    For the last decade, literature on the detrimental impacts of air pollution on brain, cognition and behavior has exponentially increased. Our aim is to review the latest epidemiologic literature on the association between outdoor air pollution and neuropsychological developmental in children. Two independent researchers searched for published studies between January 1, 2012 and June 12, 2015 in MEDLINE, Web of Science, and Science direct using defined keywords on outdoor air pollution and neuropsychological development. Selection of articles was based on study eligibility criteria. We encountered sufficient evidence of detrimental effects of pre- or postnatal exposure to polycyclic aromatic hydrocarbons on global intelligence quotient. The evidence was also sufficient for the association between pre- or postnatal exposure to fine particulate matter (PM2.5) and autism spectrum disorder, and limited evidence was encountered between nitrogen oxides and autism spectrum disorder. For other exposure-outcome associations reviewed, the evidence was inadequate or insufficient. Although evidence is not yet conclusive and further research is needed, the latest epidemiological studies support the hypothesis that pre- or postnatal exposure to ambient pollution, particularly polycyclic aromatic hydrocarbons, PM2.5, and nitrogen oxides has a negative impact on the neuropsychological development of children. The public health impact of air pollutants cannot be ignored and the precautionary principle should be applied to protect children.

  11. General practitioners' attitudes towards research in primary care: qualitative results of a cross sectional study

    Science.gov (United States)

    Rosemann, Thomas; Szecsenyi, Joachim

    2004-01-01

    Background Research in General Practice requires the participation of General practitioners (GPs). In Germany there is little tradition of research in this field, and GPs are not used to be participants in research. Little is known about German GPs attitudes towards research. Therefore the aim of our study was to assess the willingness of German General Practitioners to participate in primary care research and their attitude towards research in general practice. The results should enable a more successful approach to GPs in further studies. Methods Cross sectional study using semi-structured interviews with a random sample of 76 General Practitioners who participate in the teaching of medical students at the University of Heidelberg. Results Despite little experience, over 85 % of GPs appreciated research in their field. Important reasons for scepticism about research were the gap between theoretical research and practical work of GPs and the domination of research by specialists. Main barriers for participation are clinical workload, administrative overload and the newly introduced Disease Management Programs. The highest motivation for GPs to participate in research emanates from the will to substantiate their quality of care with solid research data. Conclusions Financial incentives and personal support e.g. with study nurses are certainly necessary to establish a research culture and to overcome main barriers against participation. The most successful approach to motivate GPs to participate is to convince them that research documents their quality of care. This data may reflect the facts on which the financial resources are provided in the future health care system. PMID:15613246

  12. Prevalence of depression, quality of life and antidepressant treatment in the Danish General Suburban Population Study

    DEFF Research Database (Denmark)

    Ellervik, Christina; Kvetny, Jan; Christensen, Kaj Sparle

    2014-01-01

    Background: The Danish General Suburban Population Study (GESUS), the objective of which is to facilitate epidemiological and genetic research, has included the Major Depression Inventory (MDI) and the WHO-Five Well-Being Index (WHO-5) among the medical health questionnaires. We were thus...... in a position to compare the 2-week prevalence of ICD-10 depression in the period from 2010 to 2012 with our previous Danish general population study from 2003, in which the MDI was also included. Aims: The aim of our analysis was not only to evaluate the point prevalence of ICD-10 depression but also...... analysis. The scalability of the MDI and the WHO-5 was quite acceptable. Results: In total, 14,787 respondents were available from a response rate of 50%. The 2-week prevalence of ICD-10 depression was 2.3%, which is rather similar to the 2.8% in our 2003 study. The rate of people receiving antidepressants...

  13. Caring for Acutely Ill Patients in General Wards: A Qualitative Study.

    Science.gov (United States)

    Jeddian, Ali Reza; Lindenmeyer, Antje; Marshall, Tom; Rashidian, Arash; Sayadi, Leila; Jafari, Nazila

    2016-09-01

    The number of acutely ill patients has risen in general wards due to the aging population, more advanced and complicated therapeutic methods, economic changes in the health system, therapeutic choices and shortage of intensive care unit beds. This may lead to adverse events and outcomes with catastrophic results. The purpose of this study was to describe the conditions of acutely ill patients, from the perspective of caregivers. The study was conducted in Tehran University of Medical Sciences and its two affiliated general teaching hospitals. Ten nurses and physicians participated in interviews, which were analyzed using qualitative content analysis methods. Four main categories of difficulties in caring for acutely ill patients in general wards were described: problems in identifying acutely ill patients, problems in clinical management of acutely ill patients, inappropriate use of Intensive Care Unit (ICU) beds, and poor structure for mortality control. The staff do not appropriately diagnose the signs of deterioration. There are problems with the appropriate management of acutely ill patients, even if they are considered to be acutely ill and in need of special attention in general wards. Many shortcomings exist caring for acutely ill patients, ranging from identification to clinical management; there are also structural and contextual problems. An immediate plan is necessary to circumvent the challenges and to improve the care for acutely ill patients. These challenges highlight the need for changes in current levels of care for acutely ill patients, as well as the need for appropriate support systems.

  14. The impact of extensive loss of telecommunications on general practice: A case study in rural Victoria.

    Science.gov (United States)

    Tran, Nancy H; Pedler, Daryl

    2017-04-01

    To describe the impact of major loss of telecommunications on general practice in a rural region of Australia. A multi-stage qualitative study. Purposively selected participants were invited to contribute to initial data collection using an online survey, followed by interviews with selected participants. Thematic analysis of the data was performed by both research team members. South-western Victoria, Australia. Individuals from organisations involved in Telstra recovery efforts, disaster management, health care and general practice staff. The survey collected freeform responses from participants. Semi-structured interviews further explored a variety of experiences from purposively selected participants. Organisations and practices in the region were prepared for major disasters, but not for the unusual and 'limited' disaster of losing telecommunications, including lack of Internet access and loss of telephone services. Although alternative measures were found for telecommunications, there was still a significant impact on many health-care-related activities and general practice functionality during the outage period. In particular, there was an increase in duties for administrative staff to compensate for loss of telecommunications. Patient traffic for many services decreased due to uncertainty about availability and continuation of business. The Warrnambool outage could be used as a case study illustrating the dramatic impact of communication loss. Major impacts include changes in patient traffic, increased administrative duties and slowing of patient care. When developing or assessing disaster management plans, general practices should consider the impact of telecommunication loss on functionality and prepare appropriate alternative, accessible and reliable measures. © 2016 National Rural Health Alliance Inc.

  15. Determinants of the clinical course of musculoskeletal complaints in general practice: design of a cohort study

    Directory of Open Access Journals (Sweden)

    van der Windt Daniëlle AWM

    2003-02-01

    Full Text Available Abstract Background Musculoskeletal complaints are frequent and have large consequences for public health. Information about the prognosis after presentation in general practice is far from complete. Knowledge about determinants of the clinical course of musculoskeletal complaints is essential for management decisions and to inform patients about their prognosis. The purpose of this study is to provide information about the prognosis of musculoskeletal complaints other than low back pain by studying the course of these complaints in general practice and to identify determinants of this course. Methods Patients of 18 years and older, who present in general practice with a new episode of a musculoskeletal complaint of the neck, shoulder, elbow, wrist, hand, arm, hip, knee, ankle or foot, are recruited by their general practitioner (GP. Participants will receive complaint-specific questionnaires by mail at baseline and after 3, 6, 12 and 18 months. The following putative determinants of the course of the complaints will be investigated: sociodemographic characteristics, characteristics of the complaint, psychosocial job characteristics, physical workload, physical activity during leisure time, pain coping, mood, kinesiophobia, social support, optimism. The primary outcomes are perceived recovery, pain, functional status, sick leave and overall quality of life.

  16. A comparative study of pain following endodontic treatment under general anesthesia

    Directory of Open Access Journals (Sweden)

    Feizi Ghader

    2015-01-01

    Full Text Available   Background and Aims: Postoperativee endodontic pain is an outstanding problem for dental patients. Therefore, a successful management of endodontic pain has become as one of the main dental objectives. The aim of the present study was to compare the postoperative endodontic pain in patients under general anesthesia versus local anesthesia.   Materials and Methods: For conducting this clinical trial study, 50 patients having mandibular molars candidate for root canal therapy were selected. Twenty-five patients treated under general anesthesia because of their fear, anxiety or gag reflex. Other 25 patients treated under local anesthesia. All teeth were prepared using engine-driven rotary system in a crown-down technique and filled using lateral condensation technique. Heft- parker visual analog scale was used to measure the degree of pain at 6, 12, 24, and 48 hours after the treatment. Mann-Whitney, Chi-square, and T-tests were used to compare the intensity of postoperative pain between the groups.   Results: The mean intensity of postoperative pain in local and general anesthesia groups at 6, 12 and 24 hours had statistically significant difference (P<0.05.   Conclusion: Postoperative pain in patients who treated under general anesthesia was significantly less than the patients who treated under local anesthesia.

  17. First Clarkforkian equivalent Land Mammal Age in the latest Paleocene basal Sparnacian facies of Europe: fauna, flora, paleoenvironment and (biostratigraphy.

    Directory of Open Access Journals (Sweden)

    Thierry Smith

    Full Text Available The Paleocene-Eocene Thermal Maximum (PETM is correlated with the first occurrences of earliest modern mammals in the Northern Hemisphere. The latest Paleocene Clarkforkian North American Land Mammal Age, that has yielded rodents and carnivorans, is the only exception to this rule. However, until now no pre-PETM localities have yielded modern mammals in Europe or Asia. We report the first Clarkforkian equivalent Land Mammal Age in the latest Paleocene deposits of the basal Sparnacian facies at Rivecourt, in the north-central part of the Paris Basin. The new terrestrial vertebrate and macroflora assemblages are analyzed through a multidisciplinary study including sedimentologic, stratigraphic, isotopic, and palynological aspects in order to reconstruct the paleoenvironment and to evaluate biochronologic and paleogeographic implications. The mammals are moderately diverse and not abundant, contrary to turtles and champsosaurs. The macroflora is exceptional in preservation and diversity with numerous angiosperms represented by flowers, fruits, seeds and wood preserved as lignite material, revealing an abundance of Arecaceae, Betulaceae, Icacinaceae, Menispermaceae, Vitaceae and probably Cornaceae. Results indicate a Late Paleocene age based on carbon isotope data, palynology and vertebrate occurrences such as the choristoderan Champsosaurus, the arctocyonid Arctocyon, and the plesiadapid Plesiadapis tricuspidens. However, several mammal species compare better with the earliest Eocene. Among these, the particular louisinid Teilhardimys musculus, also recorded from the latest Paleocene of the Spanish Pyrenees, suggests a younger age than the typical MP6 reference level. Nevertheless, the most important aspect of the Rivecourt fauna is the presence of dental remains of a rodent and a "miacid" carnivoran, attesting to the presence of two modern mammalian orders in the latest Paleocene of Europe. Interestingly, these two groups are also the only modern

  18. Increasing general practitioners' confidence and self-efficacy in managing obesity: a mixed methods study

    Science.gov (United States)

    Haesler, Emily; Elmitt, Nicholas; van Weel, Chris; Douglas, Kirsty

    2017-01-01

    Objectives Internationally, general practitioners (GPs) are being encouraged to take an active role in the care of their patients with obesity, but as yet there are few tools for them to implement within their clinics. This study assessed the self-efficacy and confidence of GPs before and after implementing a weight management programme in their practice. Design Nested mixed methods study within a 6-month feasibility trial. Setting 4 urban general practices and 1 rural general practice in Australia. Participants All vocationally registered GPs in the local region were eligible and invited to participate; 12 GPs were recruited and 11 completed the study. Interventions The Change Programme is a structured GP-delivered weight management programme that uses the therapeutic relationship between the patient and their GP to provide holistic and person-centred care. It is an evidence-based programme founded on Australian guidelines for the management of obesity in primary care. Primary outcome measures Self-efficacy and confidence of the GPs when managing obesity was measured using a quantitative survey consisting of Likert scales in conjunction with pro forma interviews. Results In line with social cognitive theory, GPs who experienced performance mastery during the pilot intervention had an increase in their confidence and self-efficacy. In particular, confidence in assisting and arranging care for patients was improved as demonstrated in the survey and supported by the qualitative data. Most importantly from the qualitative data, GPs described changing their usual practice and felt more confident to discuss obesity with all of their patients. Conclusions A structured management tool for obesity care in general practice can improve GP confidence and self-efficacy in managing obesity. Enhancing GP ‘professional self-efficacy’ is the first step to improving obesity management within general practice. Trial registration number ACTRN12614001192673; Results. PMID:28132016

  19. COMPARATIVE STUDY OF SPINAL ANESTHESIA AND GENERAL ANESTHESIA IN CHILDREN UNDERGOING SURGERIES BELOW UMBILICUS

    Directory of Open Access Journals (Sweden)

    Ashish

    2014-09-01

    Full Text Available AIM: Aim of our study to compare the spinal anaesthesia and general anaesthesia in children undergoing surgeries below umbilicus. OBJECTIVE: to assess the patient comfort in pt. with GA and pt. with spinal anaesthesia, the adequate surgical condition, assess the hemodynamic change, assess the post op analgesia and to assess the post op complication. MATERIAL AND METHOD: 60 ASA grade I & II children of either sex, aged 5-12 yrs undergoing elective surgeries for the lower abdominal, perineal and lower limb surgeries were taken. After taking a detailed history, thorough general physical examination, all pertinent investigation were carried out to exclude any systemic disease. Patients were classified randomly into 2 groups (30 patients in each group. Group A: General anesthesia was given. Group P: subarachnoid block was given. Intraoperative monitoring consisted of SPO2, PR, NIBP, RR and assessment of duration of post-operative analgesia. P-value <0.05 consider significant. RESULT: Analysis revealed that there were no significant differences between the patients with respect to age, sex, duration and type of surgery In SAB since less general anaesthetic drug including parental opioid are used the risk and postoperative respiratory depression is minimal. The stress response to surgery is also limited and recovery is fast. Postoperatively complications like sore throat, laryngeal irritation, cough etc. was also less associated with it. CONCLUSION pediatric spinal anesthesia is not only a safe alternative to general anesthesia but often the anesthesia technique of choice in many lower abdominal and lower limb surgeries in children. The misconception regarding its safety and flexibility is broken and is now found to be even more cost effective. It is much preferred technique special for common day case surgeries generally performed in the pediatric age group.

  20. Genome-wide association study of generalized anxiety symptoms in the Hispanic Community Health Study/Study of Latinos.

    Science.gov (United States)

    Dunn, Erin C; Sofer, Tamar; Gallo, Linda C; Gogarten, Stephanie M; Kerr, Kathleen F; Chen, Chia-Yen; Stein, Murray B; Ursano, Robert J; Guo, Xiuqing; Jia, Yucheng; Qi, Qibin; Rotter, Jerome I; Argos, Maria; Cai, Jianwen; Penedo, Frank J; Perreira, Krista; Wassertheil-Smoller, Sylvia; Smoller, Jordan W

    2017-03-01

    Although generalized anxiety disorder (GAD) is heritable and aggregates in families, no genomic loci associated with GAD have been reported. We aimed to discover potential loci by conducting a genome-wide analysis of GAD symptoms in a large, population-based sample of Hispanic/Latino adults. Data came from 12,282 participants (aged 18-74) in the Hispanic Community Health Study/Study of Latinos. Using a shortened Spielberger Trait Anxiety measure, we analyzed the following: (i) a GAD symptoms score restricted to the three items tapping diagnostic features of GAD as defined by DSM-V; and (ii) a total trait anxiety score based on summing responses to all ten items. We first calculated the heritability due to common variants (h(2)SNP ) and then conducted a genome-wide association study (GWAS) of GAD symptoms. Replication was attempted in three independent Hispanic cohorts (Multi-Ethnic Study of Atherosclerosis, Women's Health Initiative, Army STARRS). The GAD symptoms score showed evidence of modest heritability (7.2%; P = 0.03), while the total trait anxiety score did not (4.97%; P = 0.20). One genotyped SNP (rs78602344) intronic to thrombospondin 2 (THBS2) was nominally associated (P = 5.28 × 10(-8) ) in the primary analysis adjusting for psychiatric medication use and significantly associated with the GAD symptoms score in the analysis excluding medication users (P = 4.18 × 10(-8) ). However, meta-analysis of the replication samples did not support this association. Although we identified a genome-wide significant locus in this sample, we were unable to replicate this finding. Evidence for heritability was also only detected for GAD symptoms, and not the trait anxiety measure, suggesting differential genetic influences within the domain of trait anxiety. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

  1. A framework for developing rural academic general practices: a qualitative case study in rural Victoria.

    Science.gov (United States)

    Brown, J B; Morrison, Tracy; Bryant, Melanie; Kassell, Lisa; Nestel, Debra

    2015-01-01

    There is increasing pressure for Australian rural general practices to engage in educational delivery as a means of addressing workforce issues and accommodating substantial increases in learners. For practices that have now developed a strong focus on education, there is the challenge to complement this by engaging in research activity. This study develops a rural academic general practice framework to assist rural practices in developing both comprehensive educational activity and a strong research focus thus moving towards functioning as mature academic units. A case study research design was used with the unit of analysis at the level of the rural general practice. Purposively sampled practices were recruited and individual interviews conducted with staff (supervisors, practice managers, nurses), learners (medical students, interns and registrars) and patients. Three practices hosted 'multi-level learners', two practices hosted one learner group and one had no learners. Forty-four individual interviews were conducted with staff, learners and patients. Audio recordings were transcribed for thematic analysis. After initial inductive coding, deductive analysis was undertaken with reference to recent literature and the expertise of the research team resulting in the rural academic general practice framework. Three key themes emerged with embedded subthemes. For the first theme, organisational considerations, subthemes were values/vision/culture, patient population and clinical services, staffing, physical infrastructure/equipment, funding streams and governance. For the second theme, educational considerations, subthemes were processes, clinical supervision, educational networks and learner presence. Third, for research considerations, there were the subthemes of attitude to research and research activity. The framework maps the development of a rural academic practice across these themes in four progressive stages: beginning, emerging, consolidating and

  2. General Intelligence, Emotional Intelligence and Academic Knowledge as Predictors of Creativity Domains: A Study of Gifted Students

    Science.gov (United States)

    Sahin, Feyzullah

    2016-01-01

    Creativity of the individual is dependent on numerous factors, such as knowledge, general intelligence and emotional intelligence. The general purpose of this study is to investigate the effect of general intelligence, emotional intelligence and academic knowledge on the emerging of domain-specific creativity. The study was conducted on 178…

  3. Comparison of physiotherapy, manipulation, and corticosteroid injection for treating shoulder complaints in general practice : Randomised, single blind study

    NARCIS (Netherlands)

    Winters, Jan C.; Sobel, J.S.; Groenier, Klaas H.; Arendzen, J.H.; Meyboom-de Jong, B.

    1997-01-01

    Objective: To compare the efficacy of physiotherapy, manipulation, and corticosteroid injection for treating patients with shoulder complaints in general practice. Design: Randomised, single blind study. Setting: Seven general practices in the Netherlands. Subjects: 198 patients with shoulder compla

  4. Comparison of physiotherapy, manipulation, and corticosteroid injection for treating shoulder complaints in general practice : Randomised, single blind study

    NARCIS (Netherlands)

    Winters, Jan C.; Sobel, J.S.; Groenier, Klaas H.; Arendzen, J.H.; Meyboom-de Jong, B.

    1997-01-01

    Objective: To compare the efficacy of physiotherapy, manipulation, and corticosteroid injection for treating patients with shoulder complaints in general practice. Design: Randomised, single blind study. Setting: Seven general practices in the Netherlands. Subjects: 198 patients with shoulder

  5. General practitioners' reasoning when considering the diagnosis heart failure: a think-aloud study

    Directory of Open Access Journals (Sweden)

    Bring Johan

    2005-01-01

    Full Text Available Abstract Background Diagnosing chronic heart failure is difficult, especially in mild cases or early in the course of the disease, and guidelines are not easily implemented in everyday practice. The aim of this study was to investigate general practitioners' diagnostic reasoning about patients with suspected chronic heart failure in comparison with recommendations in European guidelines. Methods Think-aloud technique was used. Fifteen general practitioners reasoned about six case vignettes, representing authentic patients with suspected chronic heart failure. Information about each case was added successively in five steps. The general practitioners said their thoughts aloud while reasoning about the probability of the patient having chronic heart failure, and tried to decide about the diagnosis. Arguments for and against chronic heart failure were analysed and compared to recommendations in guidelines. Results Information about ejection fraction was the most frequent diagnostic argument, followed by information about cardiac enlargement or pulmonary congestion on chest X-ray. However, in a third of the judgement situations, no information about echocardiography was utilized in the general practitioners' diagnostic reasoning. Only three of the 15 doctors used information about a normal electrocardiography as an argument against chronic heart failure. Information about other cardio-vascular diseases was frequently used as a diagnostic argument. Conclusions The clinical information was not utilized to the extent recommended in guidelines. Some implications of our study are that 1 general practitioners need more information about how to utilize echocardiography when diagnosing chronic heart failure, 2 guidelines ought to give more importance to information about other cardio-vascular diseases in the diagnostic reasoning, and 3 guidelines ought to treat the topic of diastolic heart failure in a clearer way.

  6. A reliability generalization study of coefficient alpha for the life orientation test.

    Science.gov (United States)

    Vassar, Matt; Bradley, Greg

    2010-07-01

    Dispositional optimism is a widely studied construct in social science and medicine associated with a variety of important psychological and physiological outcomes. Our purpose in this study was to examine coefficient alpha for a popular optimism measure: The Life Orientation Test (LOT; Scheier & Carver, 1985). We utilized a meta-analytic procedure known as reliability generalization to provide an aggregate estimate of coefficient alpha across empirical studies that have employed the scale over time and across populations. Furthermore, we identified sample and demographic characteristics associated with variance in coefficient alpha. We discuss conditions associated with variability in coefficient alpha and provide suggestions for continued research for the LOT.

  7. Recommendations for describing statistical studies and results in general readership science and engineering journals.

    Science.gov (United States)

    Gardenier, John S

    2012-12-01

    This paper recommends how authors of statistical studies can communicate to general audiences fully, clearly, and comfortably. The studies may use statistical methods to explore issues in science, engineering, and society or they may address issues in statistics specifically. In either case, readers without explicit statistical training should have no problem understanding the issues, the methods, or the results at a non-technical level. The arguments for those results should be clear, logical, and persuasive. This paper also provides advice for editors of general journals on selecting high quality statistical articles without the need for exceptional work or expense. Finally, readers are also advised to watch out for some common errors or misuses of statistics that can be detected without a technical statistical background.

  8. Theory and interpretation in qualitative studies from general practice: Why and how?

    Science.gov (United States)

    Malterud, Kirsti

    2016-03-01

    In this article, I want to promote theoretical awareness and commitment among qualitative researchers in general practice and suggest adequate and feasible theoretical approaches. I discuss different theoretical aspects of qualitative research and present the basic foundations of the interpretative paradigm. Associations between paradigms, philosophies, methodologies and methods are examined and different strategies for theoretical commitment presented. Finally, I discuss the impact of theory for interpretation and the development of general practice knowledge. A scientific theory is a consistent and soundly based set of assumptions about a specific aspect of the world, predicting or explaining a phenomenon. Qualitative research is situated in an interpretative paradigm where notions about particular human experiences in context are recognized from different subject positions. Basic theoretical features from the philosophy of science explain why and how this is different from positivism. Reflexivity, including theoretical awareness and consistency, demonstrates interpretative assumptions, accounting for situated knowledge. Different types of theoretical commitment in qualitative analysis are presented, emphasizing substantive theories to sharpen the interpretative focus. Such approaches are clearly within reach for a general practice researcher contributing to clinical practice by doing more than summarizing what the participants talked about, without trying to become a philosopher. Qualitative studies from general practice deserve stronger theoretical awareness and commitment than what is currently established. Persistent attention to and respect for the distinctive domain of knowledge and practice where the research deliveries are targeted is necessary to choose adequate theoretical endeavours. © 2015 the Nordic Societies of Public Health.

  9. Implementing evidence-based medicine in general practice: a focus group based study

    Directory of Open Access Journals (Sweden)

    Aertgeerts Bert

    2005-09-01

    Full Text Available Abstract Background Over the past years concerns are rising about the use of Evidence-Based Medicine (EBM in health care. The calls for an increase in the practice of EBM, seem to be obstructed by many barriers preventing the implementation of evidence-based thinking and acting in general practice. This study aims to explore the barriers of Flemish GPs (General Practitioners to the implementation of EBM in routine clinical work and to identify possible strategies for integrating EBM in daily work. Methods We used a qualitative research strategy to gather and analyse data. We organised focus groups between September 2002 and April 2003. The focus group data were analysed using a combined strategy of 'between-case' analysis and 'grounded theory approach'. Thirty-one general practitioners participated in four focus groups. Purposeful sampling was used to recruit participants. Results A basic classification model documents the influencing factors and actors on a micro-, meso- as well as macro-level. Patients, colleagues, competences, logistics and time were identified on the micro-level (the GPs' individual practice, commercial and consumer organisations on the meso-level (institutions, organisations and health care policy, media and specific characteristics of evidence on the macro-level (policy level and international scientific community. Existing barriers and possible strategies to overcome these barriers were described. Conclusion In order to implement EBM in routine general practice, an integrated approach on different levels needs to be developed.

  10. Health promotion and disease prevention in general practice and primary care: a scoping study.

    Science.gov (United States)

    Peckham, Stephen; Hann, Alison; Kendall, Sally; Gillam, Steve

    2017-08-11

    This paper reports the findings of a scoping review on the organisation and delivery of health improvement activities in general practice and the primary healthcare team. The project was designed to examine who delivers these interventions, where they are located, what approaches are developed in practices and how individual practices and the primary healthcare team organise such public health activities and how these contribute to health improvement. Our focus was on health promotion and prevention activities and aimed to identify the current extent of knowledge about the health improvement activities in general practice and the wider primary healthcare team. Many of the research studies reviewed had some details about the type, process, location or who provided the intervention. Little attention is paid in the literature to examining the impact of the organisational context on the way services are delivered or how this affects the effectiveness of health improvement interventions in general practice. We found that the focus of attention is mainly on individual prevention approaches with practices engaging in both primary and secondary prevention. Although many GPs do not take a population approach and focus on individual patients some do see health promotion as an integral part of practice - whether as individual approaches to primary or secondary health improvement or as a practice-based approach to improving the health of their patients. Based on our analysis we conclude that there is insufficient good evidence to support many of the health improvement interventions undertaken in general practice and primary care.

  11. SPINAL ANAESTHESIA VERSUS GENERAL ANAESTHESIA FOR LAPAROSCOPIC CHOLECYSTECTOMY - A PROSPECTIVE RANDOMIZED CONTROLLED STUDY

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    Prasad

    2014-02-01

    Full Text Available INTRODUCTION: Combining minimal invasive surgical and lesser invasive anesthesia technique reduces morbidity and mortality. The aim of the study is to compare spinal anesthesia with the gold standard general anesthesia for elective laparoscopic cholecystectomy. MATERIALS & METHODS: 60 healthy patients were randomized under spinal anesthesia (n=30 & General Anesthesia (n=30 . Hyperbaric 3ml bupivacaine plus 25mcg fenta nyl was administered for spinal group and conventional general anesthesia for GA group. Intraoperative parameters and post - operative pain and recovery were noted. Under spinal group any intraoperative discomfort were taken care by reassurance , drugs or con verted to GA. Questionnaire forms were provided for patients and surgeons to comment about the operation. RESULTS: None of the patients had significant hemodynamic and respiratory disturbance except for transient hypotension and bradycardia. Operative time was comparable. 6patients under spinal anesthesia had right shoulder pain , 2 patients were converted to GA and 4 patients were managed by injection midazolam and infiltration of lignocaine over the diaphragm. There was significant post - operative pain reli ef in spinal group. All the patients were comfortable and surgeons satisfied. CONCLUSION: Spinal anesthesia is adequate and safe for laparoscopic cholecystectomy in otherwise healthy patients and offers better postoperative pain control than general anesth esia without limiting recovery , but require cooperative patient , skilled surgeon , a gentle surgical technique and an enthusiastic anesthesiologist

  12. Study on generalized magneto-thermoelastic problems by FEM in time domain

    Institute of Scientific and Technical Information of China (English)

    Xiaogeng Tian; Yapeng Shen; Yunming Chen

    2005-01-01

    This paper presents an investigation of temperature, displacement, stress, and induced magnetic field in a half space perfectly-conductive plate. Finite element equations regarding generalized magneto-thermoelasticity problems with two relaxation times (i.e., the G-L theory) are derived using the principle of virtual work. For avoiding numerical complication involved in inverse Laplace and Fourier transformation and low precision thereof, the equations are solved directly in time-domain. As a numerical example, the derived equation is used to investigate the generalized magneto-thermoelastic behavior of a semi-infinite plate under magnetic field and subjecting to a thermal shock loading. The results demonstrate that FEM can faithfully predict the deformation of the plate and the induced magnetic field, and most importantly can reveal the sophisticated second sound effect of heat conduction in two-dimensional generalized thermo elastic solids, which is usually difficult to model by routine transformation methods. A peak can be observed in the distribution of stress and induced magnetic field at the heat wave front and the magnitude of the peak decreases with time, which can not be obtained by transformation methods. The new method can also be used to study generalized piezo-thermoelastic problems.

  13. Rhinosinusitis in morbidity registrations in Dutch General Practice: a retro-spective case-control study

    OpenAIRE

    2015-01-01

    BACKGROUND: There is only limited accurate data on the epidemiology of rhinosinusitis in primary care. This study was conducted to assess the incidence of acute and chronic rhinosinusitis by analysing data from two Dutch general practice registration projects. Several patient characteristics and diseases are related to the diagnosis rhinosinusitis. METHODS: The Continuous Morbidity Registration (CMR) and the Transitionproject (TP) are used to analyse the data on rhinosinusitis in primary prac...

  14. A qualitative study on nurses' reactions to inpatient suicide in a general hospital

    Directory of Open Access Journals (Sweden)

    Shujie Wang

    2016-12-01

    Conclusions: Nurses who experienced inpatient suicide became stressed. Effective interventions must be implemented to improve the coping mechanisms of nurses against the negative consequences of inpatient suicide. The findings of this study will allow administrators to gain insight into the impacts of inpatient suicides on nurses in general hospitals. Such information can be used to develop effective strategies and provide individual support and ongoing education. Consequently, nurses will acquire suicide prevention skills and help patients achieve swift recovery.

  15. SEASAT economic assessment. Volume 3: Offshore oil and natural gas industry case study and generalization

    Science.gov (United States)

    1975-01-01

    The economic benefits of improved ocean condition, weather and ice forecasts by SEASAT satellites to the exploration, development and production of oil and natural gas in the offshore regions are considered. The results of case studies which investigate the effects of forecast accuracy on offshore operations in the North Sea, the Celtic Sea, and the Gulf of Mexico are reported. A methodology for generalizing the results to other geographic regions of offshore oil and natural gas exploration and development is described.

  16. Nitrogen-gas-stream cryostat for general X-ray diffraction studies

    Energy Technology Data Exchange (ETDEWEB)

    Cosier, J.; Glazer, A.M.

    1986-04-01

    A continuous nitrogen-flow cooling device, generally applicable to X-ray diffraction studies, is described. The device works in the range 77.4 to 323.0 K with a precision of +-0.1 K and a liquid-nitrogen constant consumption rate of 0.5 l h/sup -1/ over the whole temperature range. The supply vessel is unpressurised, so that refilling can be done without any observable influence on the cooling of the sample.

  17. Devry NR447 full course latest 2015 october [ all Week Discussion and all assignments

    OpenAIRE

    Laynebaril

    2017-01-01

     Devry NR447 full course latest 2015 october [ all Week Discussion and all assignments ] Click Link Below To Buy: http://hwcampus.com/shop/nr447-full-course-latest/   Devry NR447 Week 1 Discussion 1 & 2 Latest 2015 October Discussion 1 Review the Huston (2010) article listed under reading assignments. Which skills described for the Nurse Leader in the year 2020 are important now? Explain your rationale and provide an example from your practice setting (or from y...

  18. Study of Differentiation of Self and General Health in High School Students

    Directory of Open Access Journals (Sweden)

    Dena Adili

    2012-09-01

    Full Text Available Background: According to the Bowen Family System Theory, the differentiation level is associated with lower anxiety. The aim of this study was to evaluate more broadly the relationship between differentiation and other indicators of public health (anxiety, depression, physical discomforts, and social dysfunction in Iranian culture. Materials and Methods: This descriptive-correlation study was conducted on third-grade boy and girl high school students in district 5, Tehran. The study sample consisted of 320 third grade high school students randomly selected from the four geographical corners of this district (160 girls and 160 boys. The subjects completed the 28-item version of the Goldberg General Health Questionnaire and the Differentiation Inventory designed by Skowron. The results were analyzed by SPSS-14 statistical software through Pearson correlation, multivariate regression analysis, and t-test statistical methods.Results: The results of regression analysis in the t-test showed a significant relationship between differentiation level and general health of students at the level of 0.99.Conclusion: People with higher differentiation (emotional reactivity, fusion with others, less emotional cutoff, and clearer I-position have better general health. The findings confirm the Bowen System Theory.

  19. Self-rescue swimming in cold water: the latest advice.

    Science.gov (United States)

    Ducharme, Michel B; Lounsbury, David S

    2007-08-01

    According to the 2006 Canadian Red Cross Drowning Report, 2007 persons died of cold-water immersion in Canada between 1991 and 2000. These statistics indicate that prevention of cold-water immersion fatalities is a significant public health issue for Canadians. What should a person do after accidental immersion in cold water? For a long time, aquatic safety organizations and government agencies stated that swimming should not be attempted, even when a personal flotation device (PFD) is worn. The objective of the present paper is to present the recent scientific evidence making swimming a viable option for self-rescue during accidental cold-water immersion. Early studies in the 1960s and 1970s led to a general conclusion that "people are better off if they float still in lifejackets or hang on to wreckage and do not swim about to try to keep warm". Recent evidence from the literature shows that the initial factors identified as being responsible for swimming failure can be either easily overcome or are not likely the primary contributors to swimming failure. Studies over the last decade reported that swimming failure might primarily be related not to general hypothermia, but rather to muscle fatigue of the arms as a consequence of arm cooling. This is based on the general observation that swimming failure developed earlier than did systemic hypothermia, and can be related to low temperature of the arm muscles following swimming in cold water. All of the above studies conducted in water between 10 and 14 degrees C indicate that people can swim in cold water for a distance ranging between about 800 and 1500 m before being incapacitated by the cold. The average swimming duration for the studies was about 47 min before incapacitation, regardless of the swimming ability of the subjects. Recent evidence shows that people have a very accurate idea about how long it will take them to achieve a given swimming goal despite a 3-fold overestimation of the absolute distance to

  20. Continuous positive airway pressure for bronchiolitis in a general paediatric ward; a feasibility study

    Science.gov (United States)

    2014-01-01

    Background Continuous positive airway pressure (CPAP) is commonly used to relieve respiratory distress in infants with bronchiolitis, but has mostly been studied in an intensive care setting. Our prime aim was to evaluate the feasibility of CPAP for infants with bronchiolitis in a general paediatric ward, and secondary to assess capillary PCO2 (cPCO2) levels before and during treatment. Methods From May 1st 2008 to April 30th 2012, infants with bronchiolitis at Stavanger University Hospital were treated with CPAP in a general paediatric ward, but could be referred to an intensive care unit (ICU) when needed, according to in-house guidelines. Levels of cPCO2 were prospectively registered before the start of CPAP and at approximately 4, 12, 24 and 48 hours of treatment as long as CPAP was given. We had a continuous updating program for the nurses and physicians caring for the infants with CPAP. The study was population based. Results 672 infants (3.4%) were hospitalized with bronchiolitis. CPAP was initiated in 53 infants (0.3%; 7.9% of infants with bronchiolitis), and was well tolerated in all but three infants. 46 infants were included in the study, the majority of these (n = 33) were treated in the general ward only. These infants had lower cPCO2 before treatment (8.0; 7.7, 8.6)(median; quartiles) than those treated at the ICU (n = 13) (9.3;8.5, 9.9) (p bronchiolitis may be feasible in a general paediatric ward, providing sufficient staffing and training, and the possibility of referral to an ICU when needed. PMID:24886569

  1. Experiences of using email for general practice consultations: a qualitative study.

    Science.gov (United States)

    Atherton, Helen; Pappas, Yannis; Heneghan, Carl; Murray, Elizabeth

    2013-11-01

    Reports suggest approximately 21-23% of GPs in the UK have consulted with patients using email, but little is known about the nature of this use and what it means for clinicians and patients in general practice. To understand the use of email consultation in general practice by investigating the experiences of existing users and views of experts. A qualitative study conducted in 2010 using purposive sampling and semi-structured interviews in general practice and community settings in some London boroughs. A maximum variation sample of GPs and patients who had used email for consultation in general practice were recruited, as were policy and/or implementation experts. Interviews continued until saturation was achieved. In total 10 GPs, 14 patients, and six experts were interviewed. Consultation by email was often triggered by logistic or practical issues; motivators for ongoing use were the benefits, such as convenience, for GPs and patients. Both GPs and patients reported concerns about safety and lack of guidance about the 'rules of engagement' in email consultations, with GPs also concerned about workload. In response, both groups attempted to introduce their own rules, although this only went some way to addressing uncertainty. Long term, participants felt there was a need for regulation and guidance. Consultations by email in general practice occur in an unregulated and unstructured way. Current UK policy is to promote consultations by email, making it crucial to consider the responsibility and workload faced by clinicians, and the changes required to ensure safe use; not doing so may risk safety breaches and result in suboptimal care for patients.

  2. Laparoscopic total extraperitoneal repair under spinal anesthesia versus general anesthesia: a randomized prospective study

    Directory of Open Access Journals (Sweden)

    Donmez T

    2016-10-01

    Full Text Available Turgut Donmez,1 Vuslat Muslu Erdem,2 Oguzhan Sunamak,3 Duygu Ayfer Erdem,2 Huseyin Imam Avaroglu1 1Department of General Surgery, 2Department of Anesthesiology and Reanimation, Lutfiye Nuri Burat State Hospital, 3Department of General Surgery, Haydarpasa Numune Training and Research Hospital, Istanbul, Turkey Background: Laparoscopic total extraperitoneal (TEP inguinal hernia repair is a well-known approach to inguinal hernia repair that is usually performed under general anesthesia (GA. To date, no reports compare the efficacy of spinal anesthesia (SA with that of GA for laparoscopic hernia repairs. The purpose of this study was to compare the surgical outcome of TEP inguinal hernia repair performed when the patient was treated under SA with that performed under GA. Materials and methods: Between July 2015 and July 2016, 50 patients were prospectively randomized to either the GA TEP group (Group I or the SA TEP group (Group II. Propofol, fentanyl, rocuronium, sevoflurane, and tracheal intubation were used for GA. Hyperbaric bupivacaine (15 mg and fentanyl (10 µg were used for SA to achieve a sensorial level of T3. Intraoperative events related to SA, operative and anesthesia times, postoperative complications, and pain scores were recorded. Each patient was asked to evaluate the anesthetic technique by using a direct questionnaire filled in 3 months after the operation. Results: All the procedures were completed by the allocated method of anesthesia as there were no conversions from SA to GA. Pain was significantly less for 1 h (P<0.0001 and 4 h (P=0.002 after the procedure for the SA and GA groups, respectively. There was no difference between the two groups regarding complications, hospital stay, recovery, or surgery time. Generally, patients were more satisfied with SA than GA (P<0.020. Conclusion: TEP inguinal hernia repair can be safely performed under SA, and SA was associated with less postoperative pain, better recovery, and better

  3. Prioritization of future genetics education for general practitioners: a Delphi study

    Science.gov (United States)

    Houwink, Elisa J.F.; Henneman, Lidewij; Westerneng, Myrte; van Luijk, Scheltus J.; Cornel, Martina C.; Dinant, Jan Geert; Vleuten, Cees van der

    2012-01-01

    Purpose: General practitioners (GPs) are increasingly expected to deliver genetics services in daily patient care. Education in primary care genetics is considered suboptimal and in urgent need of revision and innovation. The aim of this study was to prioritize topics for genetics education for general practice. Methods: A Delphi consensus procedure consisting of three rounds was conducted. A purposively selected heterogeneous panel (n = 18) of experts, comprising six practicing GPs who were also engaged in research, five GP trainers, four clinical genetics professionals, and three representatives of patient organizations, participated. Educational needs regarding genetics in general practice in terms of knowledge, skills, and attitudes were rated and ranked in a top-10 list. Results: The entire panel completed all three rounds. Kendall's coefficient of concordance indicated significant agreement regarding the top 10 genetic education needs (P < 0.001). “Recognizing signals that are potentially indicative of a hereditary component of a disease” was rated highest, followed by “Evaluating indications for referral to a clinical genetics centre” and “Knowledge of the possibilities and limitations of genetic tests.” Conclusions: The priorities resulting from this study can inform the development of educational modules, including input for case-based education, to improve GP performance in genetic patient care. PMID:22241093

  4. The PACE study: lifetime and past-year prevalence of headache in Parma's adult general population.

    Science.gov (United States)

    Taga, Arens; Russo, Marco; Manzoni, Gian Camillo; Torelli, Paola

    2017-05-01

    Headache is a widespread disorder and therefore it has a strong impact on quality of life. In the present work we focused on lifetime and past-year prevalence of headache in general and by gender, in a population-based sample in Parma. A total of 904 subjects representative of Parma's adult general population were interviewed face-to-face by a physician from the Parma Headache Centre, using a validated questionnaire. The lifetime prevalence of headache was 69.1%, i.e. 75.8% in women and 60.6% in men; the crude past-year prevalence of headache was 42.8%, i.e. 52.0% in women and 31.1% in men. Both lifetime and past-year prevalence rates were significantly higher in females than in males (odds ratio, respectively, 2.0 and 2.4). In our study, past-year prevalence decreased after age 50 in both genders. Most people suffer from one headache subtype. In over 80% of cases, headache starts before age 40 and therefore people were not very likely to develop headache after 50 years. The past-year and lifetime prevalence rate of headache in general that we found in our study falls within the lower range of values for headache prevalence in European countries. Further researches need to be set in the Italian epidemiological background.

  5. Psychotropic drug monitoring in general practice in Italy: a two-year study.

    Science.gov (United States)

    Bellantuono, C; Fiorio, R; Williams, P; Martini, N; Bozzini, L

    1987-03-01

    A psychotropic drug monitoring study in general practice was carried out in 1983 and 1984 using a computerized drug information system. The prescription data analysed in the study came from 68 general practitioners operating in south Verona and have been collected by 14 community pharmacies located in the same area. Benzodiazepine hypnotics were the most commonly prescribed drugs, followed by antidepressants and neuroleptics both in 1983 and in 1984. The distribution of the general practitioners in terms of low, medium and high prescribers was examined by analysing the rates of prescriptions per registered patient. The rates were obtained for the total number of prescriptions and also for each of the three different classes of psychotropic drug. The proportion of low and high prescribers decreased from 1983 to 1984 (18.3 versus 11.7 and 26.7 versus 16.7 for low and high prescribers respectively); this change was mainly due to the reduction in benzodiazepine prescriptions. No significant correlation was found between the rates of psychotropic drug prescriptions and list size. The monthly variation in prescription of the three drug classes followed a similar pattern during the two years; the fluctuations were clearly cyclical, more definitely in 1984 than in 1983 where the most relevant feature was the summer trough.

  6. [Multidimensional diagnosis in general medicine. Comparative study of the use of various instruments].

    Science.gov (United States)

    Becchi, M A; Franzelli, A; Moscardelli, S; De Pieri, P; Zeni, L; Paccagnella, B

    1994-10-01

    This study was performed to test three instruments for functional status assessment in General Practice: the Dartmouth Coop Charts (COOP Charts), the Functional Status Questionnaire (FSQ) and the Duke University Health Profile (DUHP). All the instruments covered a score of functional aspects in physical, mental and social areas, providing a multidimensional measure of health status. We used these three instruments, validated by international studies, to acquire information concerning their feasibility and acceptability among patients from rural communities needing primary care and to test their validity in differentiating between patient subgroups. The COOP Charts, the FSQ and the DUHP were administered by physicians respectively to 98, 100 and 97 patients, waiting for a visit in the ambulatories of their General Practitioner. Answers relating to each instrument were analyzed according to sex, age and education of patients. All the instruments seemed to be feasible and acceptable, but only the COOP Charts and the FSQ were able to discriminate between different sex, age and scolarity groups. Taking into account the need to elaborate answers according to a formula when using the FSQ, we concluded that the best instrument for General Practice to provide a multidimensional measure of health status seems to be the COOP Charts.

  7. General practitioners' views on leadership roles and challenges in primary health care: a qualitative study.

    Science.gov (United States)

    Spehar, Ivan; Sjøvik, Hege; Karevold, Knut Ivar; Rosvold, Elin Olaug; Frich, Jan C

    2017-03-01

    To explore general practitioners' (GPs) views on leadership roles and leadership challenges in general practice and primary health care. We conducted focus groups (FGs) with 17 GPs. Norwegian primary health care. 17 GPs who attended a 5 d course on leadership in primary health care. Our study suggests that the GPs experience a need for more preparation and formal training for the leadership role, and that they experienced tensions between the clinical and leadership role. GPs recognized the need to take on leadership roles in primary care, but their lack of leadership training and credentials, and the way in which their practices were organized and financed were barriers towards their involvement. GPs experience tensions between the clinical and leadership role and note a lack of leadership training and awareness. There is a need for a more structured educational and career path for GPs, in which doctors are offered training and preparation in advance. KEY POINTS Little is known about doctors' experiences and views about leadership in general practice and primary health care. Our study suggests that: There is a lack of preparation and formal training for the leadership role. GPs experience tensions between the clinical and leadership role. GPs recognize leadership challenges at a system level and that doctors should take on leadership roles in primary health care.

  8. General practitioners’ views on leadership roles and challenges in primary health care: a qualitative study

    Science.gov (United States)

    Spehar, Ivan; Sjøvik, Hege; Karevold, Knut Ivar; Rosvold, Elin Olaug; Frich, Jan C.

    2017-01-01

    Objective To explore general practitioners’ (GPs) views on leadership roles and leadership challenges in general practice and primary health care. Design We conducted focus groups (FGs) with 17 GPs. Setting Norwegian primary health care. Subjects 17 GPs who attended a 5 d course on leadership in primary health care. Results Our study suggests that the GPs experience a need for more preparation and formal training for the leadership role, and that they experienced tensions between the clinical and leadership role. GPs recognized the need to take on leadership roles in primary care, but their lack of leadership training and credentials, and the way in which their practices were organized and financed were barriers towards their involvement. Conclusions GPs experience tensions between the clinical and leadership role and note a lack of leadership training and awareness. There is a need for a more structured educational and career path for GPs, in which doctors are offered training and preparation in advance. Key points Little is known about doctors’ experiences and views about leadership in general practice and primary health care. Our study suggests that: There is a lack of preparation and formal training for the leadership role. GPs experience tensions between the clinical and leadership role. GPs recognize leadership challenges at a system level and that doctors should take on leadership roles in primary health care. PMID:28277051

  9. Patient participation in general practice based undergraduate teaching: a focus group study of patient perspectives.

    Science.gov (United States)

    Park, Sophie E; Allfrey, Caroline; Jones, Melvyn M; Chana, Jasprit; Abbott, Ciara; Faircloth, Sofia; Higgins, Nicola; Abdullah, Laila

    2017-04-01

    Patients make a crucial contribution to undergraduate medical education. Although a national resource is available for patients participating in research, none is as yet available for education. This study aimed to explore what information patients would like about participation in general practice based undergraduate medical education, and how they would like to obtain this information. Two focus groups were conducted in London-based practices involved in both undergraduate and postgraduate teaching. Patients both with and without teaching experience were recruited using leaflets, posters, and patient participation groups. An open-ended topic guide explored three areas: perceived barriers that participants anticipated or had experienced; patient roles in medical education; and what help would support participation. Focus groups were audiorecorded, transcribed, and analysed thematically. Patients suggested ways of professionalising the teaching process. These were: making information available to patients about confidentiality, iterative consent, and normalising teaching in the practice. Patients highlighted the importance of relationships, making information available about their GPs' involvement in teaching, and initiating student-patient interactions. Participants emphasised educational principles to maximise exchange of information, including active participation of students, patient identification of student learner needs, and exchange of feedback. This study will inform development of patient information resources to support their participation in teaching and access to information both before and during general practice based teaching encounters. © British Journal of General Practice 2017.

  10. Study of Confinement/Deconfinement Transition in AdS/QCD with Generalized Warp Factors

    Directory of Open Access Journals (Sweden)

    Shobhit Sachan

    2014-01-01

    Full Text Available We study analytical solutions of charged black holes and thermally charged AdS with generalized warped factors in Einstein-Maxwell-Dilaton system. We calculate Euclidean action for charged AdS and thermally charged AdS. The actions in both backgrounds are regularized by the method of background subtraction. The study of phase transition between charged black hole and thermally charged AdS gives an insight into the confinement/deconfinement transition. The plots of grand potential versus temperature and chemical potential versus transition temperature are obtained.

  11. The role of general practitioner research groups in the study of benzodiazepines.

    Science.gov (United States)

    Harris, P G

    1983-01-01

    The advantages of a once a day regime of a long half life benzodiazepine are illustrated by a general pratitioner study in the U.K., which showed that in a group of over 100 patients, clorazepate 15 mg nocte was equally as effective as diazepam 5 mg three times a day. Another study carried out on 50 patients randomly allocated to lorazepam 1 mg t.d.s. or to clorazepate, which was directly related to the low incidence of side effects and simplicity of dosage.

  12. High workload and job stress are associated with lower practice performance in general practice: an observational study in 239 general practices in the Netherlands.

    NARCIS (Netherlands)

    Hombergh, P. van den; Kunzi, B.; Elwyn, G.; Doremalen, J.H.M. van; Akkermans, R.P.; Grol, R.P.T.M.; Wensing, M.J.P.

    2009-01-01

    BACKGROUND: The impact of high physician workload and job stress on quality and outcomes of healthcare delivery is not clear. Our study explored whether high workload and job stress were associated with lower performance in general practices in the Netherlands. METHODS: Secondary analysis of data fr

  13. An evaluation study on a university general education subject in Hong Kong.

    Science.gov (United States)

    Shek, Daniel T L; Yu, Lu

    2017-02-01

    This study evaluated a university general education subject on leadership and intrapersonal development ("Tomorrow's Leaders", TL) offered at The Hong Kong Polytechnic University (PolyU) based on an online survey using the Student Feedback Questionnaire (SFQ). At the end of the first semester of the 2013/2014 academic year, 725 Year-1 students completed the online questionnaire. Results showed that the students generally had positive ratings on both the subject attributes and the qualities of teachers. The majority of the participants perceived the subject as beneficial to their holistic development and leadership competencies. Students from the Faculty of Health and Social Sciences (FHSS) and the Faculty of Applied Science and Textiles (FAST) had more favorable evaluation of the subject than students from the Faculty of Construction and Environment (FCE). Students' perceived benefit of the subject was significantly predicted by the subject attributes and teacher attributes. Implications of the findings are discussed.

  14. A scientometric study of General Relativity and Quantum Cosmology from 2000 to 2012

    CERN Document Server

    Fay, Stephane

    2015-01-01

    2015 is the centennial of Einstein General Relativity. On this occasion, we examine the General Relativity and Quantum Cosmology (GRQC) field of research by analysing 38291 papers uploaded on the electronic archives arXiv.org from 2000 to 2012. We establish a map of the countries contributing to GRQC in 2012. We determine the main journals publishing GRQC papers and which countries publish in which journals. We find that more and more papers are written by groups (instead of single) of authors with more and more international collaborations. There are huge differences between countries. Hence Russia is the country where most of papers are written by single authors whereas Canada is one of the countries where the most of papers are written with international collaborations. We also study mobility of researchers, determining how some groups of authors spread worldwide with time for different countries. The largest mobilities (as well as international collaborations) are between USA-UK and USA-Germany. Countries...

  15. Parenteral antibiotic therapy in general practice in Italy: a direct observational study.

    Science.gov (United States)

    Sessa, A; Bettoncelli, G; Rossi, A; Giustini, S E

    2007-02-01

    The aim of this study was to determine the characteristics of parenteral antimicrobial therapy (PAT) in the general practice setting in Italy, the characteristics of patients and the presence of possible external factors (induced prescriptions). 204 General Practitioners (GPs) enrolled during a one-year period the first ten patients to whom they prescribed a PAT, collecting data about clinical characteristics, compliance, outcome and the therapy prescribed or induced. Results indicate that 1,892 patients received a PAT. The use of PAT was preferred for elderly patients. In 55.2% of cases the site of infection was in the lower respiratory tract, followed by urinary tract (14%) and upper respiratory tract (12%). In 98% of cases the route of administration was intramuscular. The first motivation for PAT was in about 50% of cases the severity of the illness, afterward the prescription induced by a specialist in 16% of cases, and in 9% of cases the failure of oral antibiotic therapy.

  16. SIMULATION STUDY OF GENERALIZED MINIMUM VARIANCE CONTROL FOR AN EXTRACTION TURBINE

    Institute of Scientific and Technical Information of China (English)

    Shi Xiaoping

    2003-01-01

    In an extraction turbine, pressure of the extracted steam and rotate speed of the rotor are two important controlled quantities. The traditional linear state feedback control method is not perfect enough to control the two quantities accurately because of existence of nonlinearity and coupling. A generalized minimum variance control method is studied for an extraction turbine. Firstly, a nonlinear mathematical model of the control system about the two quantities is transformed into a linear system with two white noises. Secondly, a generalized minimum variance control law is applied to the system.A comparative simulation is done. The simulation results indicate that precision and dynamic quality of the regulating system under the new control law are both better than those under the state feedback control law.

  17. The quality of COPD care in general practice in Denmark: the KVASIMODO study

    DEFF Research Database (Denmark)

    Lange, Peter; Rasmussen, Finn Vejlø; Borgeskov, Hanne;

    2007-01-01

    AIM: We studied the quality of care for COPD patients in a large sample of general practices in Denmark. We focussed on whether participation by general practitioners (GPs) in an educational programme could enhance the use of spirometry in the diagnosis and staging of the disease and improve...... in the second. RESULTS: Based on analysis of all patient records, we observed a substantial improvement in the quality of care: recording of FEV1 improved from 52.7% of cases in the first survey to 71.4% in the second (p....8% in the second. When analysing the results focussing on the performance of single GPs there was an improvement in quality, but this was less than the improvement for patients overall - suggesting that improvement in quality of care was not equally distributed throughout the GPs' practices. CONCLUSION: We...

  18. On the anomalies in the latest LHCb data

    Directory of Open Access Journals (Sweden)

    T. Hurth

    2016-08-01

    Full Text Available Depending on the assumptions on the power corrections to the exclusive b→sℓ+ℓ− decays, the latest data of the LHCb Collaboration – based on the 3 fb−1 data set and on two different experimental analysis methods – still shows some tensions with the Standard Model predictions. We present a detailed analysis of the theoretical inputs and various global fits to all the available b→sℓ+ℓ− data. This constitutes the first global analysis of the new data of the LHCb Collaboration based on the hypothesis that these tensions can be at least partially explained by new physics contributions. In our model-independent analysis we present one-, two-, four-, and also five-dimensional global fits in the space of Wilson coefficients to all available b→sℓ+ℓ− data. We also compare the two different experimental LHCb analyses of the angular observables in B→K⁎μ+μ−. We explicitly analyse the dependence of our results on the assumptions about power corrections, but also on the errors present in the form factor calculations. Moreover, based on our new global fits we present predictions for ratios of observables which may show a sign of lepton non-universality. Their measurements would crosscheck the LHCb result on the ratio RK=BR(B+→K+μ+μ−/BR(B+→K+e+e− in the low-q2 region which deviates from the SM prediction by 2.6σ.

  19. A search for sterile neutrinos with the latest cosmological observations

    Energy Technology Data Exchange (ETDEWEB)

    Feng, Lu; Zhang, Jing-Fei [Northeastern University, Department of Physics, College of Sciences, Shenyang (China); Zhang, Xin [Northeastern University, Department of Physics, College of Sciences, Shenyang (China); Peking University, Center for High Energy Physics, Beijing (China)

    2017-06-15

    We report the result of a search for sterile neutrinos with the latest cosmological observations. Both cases of massless and massive sterile neutrinos are considered in the ΛCDM cosmology. The cosmological observations used in this work include the Planck 2015 temperature and polarization data, the baryon acoustic oscillation data, the Hubble constant direct measurement data, the Planck Sunyaev-Zeldovich cluster counts data, the Planck lensing data, and the cosmic shear data. We find that the current observational data give a hint of the existence of massless sterile neutrino (as dark radiation) at the 1.44σ level, and the consideration of an extra massless sterile neutrino can indeed relieve the tension between observations and improve the cosmological fit. For the case of massive sterile neutrino, the observations give a rather tight upper limit on the mass, which implies that actually a massless sterile neutrino is more favored. Our result is consistent with the recent result of neutrino oscillation experiment done by the Daya Bay and MINOS collaborations, as well as the recent result of cosmic ray experiment done by the IceCube collaboration. (orig.)

  20. Latest results from the KASCADE-Grande experiment

    Energy Technology Data Exchange (ETDEWEB)

    Chiavassa, A., E-mail: achiavas@to.infn.it [Dipartimento di Fisica, Università degli Studi di Torino (Italy); Apel, W.D. [Institut für Kernphysik, KIT - Karlsruher Institut für Technologie (Germany); Arteaga-Velázquez, J.C. [Universidad Michoacana, Instituto de Física y Matemáticas, Morelia (Mexico); Bekk, K. [Institut für Kernphysik, KIT - Karlsruher Institut für Technologie (Germany); Bertaina, M. [Dipartimento di Fisica, Università degli Studi di Torino (Italy); Blümer, J. [Institut für Kernphysik, KIT - Karlsruher Institut für Technologie (Germany); Institut für Experimentelle Kernphysik, KIT - Karlsruher Institut für Technologie (Germany); Bozdog, H. [Institut für Kernphysik, KIT - Karlsruher Institut für Technologie (Germany); Brancus, I.M. [National Institute of Physics and Nuclear Engineering, Bucharest (Romania); Cantoni, E. [Dipartimento di Fisica, Università degli Studi di Torino (Italy); Osservatorio Astrofisico di Torino, INAF Torino (Italy); Cossavella, F. [Institut für Experimentelle Kernphysik, KIT - Karlsruher Institut für Technologie (Germany); Curcio, C. [Dipartimento di Fisica, Università degli Studi di Torino (Italy); Daumiller, K. [Institut für Kernphysik, KIT - Karlsruher Institut für Technologie (Germany); and others

    2014-04-01

    The KASCADE-Grande experiment operated at KIT from January 2004 to November 2012, measuring EAS generated by primary cosmic rays in the 10{sup 16}–10{sup 18} eV energy range. The experiment detected, for each single event, with a high resolution, the total number of charged particles (N{sub ch}) and of muons (N{sub μ}). In this contribution we present the latest results about: (i)The measurement of the all particle energy spectrum, discussing the influence of the hadronic interaction model used to derive the energy calibration of the experimental data. (ii)The energy spectra derived separating the events according to the N{sub μ}/N{sub ch} ratio. This technique allowed us to unveil a steepening of the spectrum of heavy primaries at E∼10{sup 16.92±0.04}eV and a hardening of the spectrum of light primaries at E∼10{sup 17.08±0.08}eV. (iii)The elemental spectra (for five mass groups) obtained applying a detailed unfolding analysis technique. (iv)A search for large scale anisotropies.

  1. Latest news on Arabidopsis brassinosteroid perception and signaling

    Directory of Open Access Journals (Sweden)

    Klaus eHarter

    2011-10-01

    Full Text Available Brassinosteroids (BR are plant hormones regulating growth and development. In interaction with other hormones, they are involved in environmental cue responses. The standard BR response pathway model in Arabidopsis includes the perception of the hormone by the plasma membrane receptor BRASSINOSTEROID INSENSITIVE 1 (BRI1 and its hetero-oligomerisation with the co-receptor BRI1-ASSOCIATED RECEPTOR KINASE 1 (BAK1, followed by the activation of a signaling cascade finally resulting in the expression of BR-responsive genes. Recent findings have shed new light on the molecular mechanism of BR perception, which includes the hormone-induced formation of a platform in BRI1 extracellular domain for interaction with BAK1, and on very early events of signaling at the plasma membrane-cytoplasm interface. In addition, a fast BR response pathway that modifies the membrane potential and the expansion of the cell wall – both crucial processes preceding cell elongation growth – was identified. In this review, these latest findings are summarized and discussed against the background of the standard model of BRI1-dependent signaling.

  2. On the anomalies in the latest LHCb data

    CERN Document Server

    Hurth, T; Neshatpour, S

    2016-01-01

    Depending on the assumptions on the power corrections to the exclusive b -> s l+ l- decays, the latest data of the LHCb collaboration - based on the 3 fb^-1 data set and on two different experimental analysis methods - still shows some tensions with the SM predictions. We present a detailed analysis of the theoretical inputs and various global fits to all the available b -> s l+ l- data. This constitutes the first global analysis of the new data of the LHCb collaboration based on the hypothesis that these tensions can be at least partially explained by new physics contributions. In our model-independent analysis we present one-, two-, four-, and also five-dimensional global fits in the space of Wilson coefficients to all available b -> s l+ l- data. We also compare the two different experimental LHCb analyses of the angular observables in B -> K* mu+ mu-. We explicitly analyse the dependence of our results on the assumptions about power corrections, but also on the errors present in the form factor calculatio...

  3. Latest trends in natural gas vehicle technology in Japan

    Energy Technology Data Exchange (ETDEWEB)

    Sato, Toshiharu [Tokyo Gas Co., Ltd. (Japan); Higashino, Koji [Osaka Gas Co., Ltd. (Japan); Usui, Akira [Toho Gas Co., Ltd. (Japan); Yamaguchi, Eiji [Saibu Gas Co., Ltd. (Japan)

    1997-11-01

    Out of the necessity for finding a solution to the air pollution and alternative fuel in Japan, the gas companies have been promoting the development and introduction of natural gas vehicles (NGVs) with the cooperation of vehicle manufacturers. The target was the development of dedicated CNG (Compressed Natural Gas) vehicles with cleaner emissions, and several types of vehicles have been achieved, from small vans to large transit buses. As at September 1996, 800 NGVs have been introduced in Japan. It is increasing steadily. They are modified from gasoline or diesel vehicles. But the vehicle manufacturers themselves are doing the modifications and much dedicated CNG vehicle technology is being included. For instance, engine combustion systems include conventional stoichiometric air fuel ratio combustion with a three-way catalyst, the lean burn system without catalyst and a combination of both using lean burn for low loads and stoichiometric ratio combustion for high loads. This report summarizes the latest trends in natural gas vehicle technology in Japan based on examples of representative types of vehicles. (au)

  4. Latest LHCb measurements of Electroweak Boson Production in Run-1

    CERN Document Server

    CERN. Geneva

    2015-01-01

    We present the latest LHCb measurements of forward Electroweak Boson Production using proton-proton collisions recorded in LHC Run-1. The seminar shall discuss measurements of the 8 TeV W & Z boson production cross-sections. These results make use of LHCb's excellent integrated luminosity determination to provide constraints on the parton distribution functions which describe the inner structure of the proton. These LHCb measurements probe a region of phase space at low Bjorken-x where the other LHC experiments have limited sensitivity. We also present measurements of cross-section ratios, and ratios of results in 7 TeV and 8 TeV proton-proton collisions. These results provide precision tests of the Standard Model. The seminar shall also present a measurement of the forward-backward asymmetry (A_FB) in Z boson decays to two muons. This result allows for precision tests of the coupling of the Z boson to left and right handed particles, providing sensitivity to the effective weak mixing angle (...

  5. Latest results on neutrino oscillation from the NOMAD experiment

    CERN Document Server

    Roda, C

    2001-01-01

    The latest results on nu /sub tau / appearance search in nu /sub mu / to nu /sub tau / and nu /sub e/ to nu /sub tau / oscillation in NOMAD are reported. The analysis, carried out on the full data sample, is based on kinematic criteria. No evidence of oscillations is found. In the two-family oscillation scenario this sets a limit on sin/sup 2/ 2 theta /sub mu tau / < 4.0 * 10/sup -4/ at large Delta m/sup 2/ and Delta m/sup 2/ < 0.7 eV/sup 2//c/sup 4/ for sin/sup 2/ 2 theta /sub mu tau / = 1 at 90% C.L.. If the results are interpreted in the nu /sub e / to nu /sub tau / oscillation hypothesis the corresponding limits are sin/sup 2/ 2 theta /sub e tau / < 2.0 * 10/sup -2/ at large Delta m /sup 2/ and Delta m/sup 2/ < 6 eV/sup 2//c/sup 4/ for sin/sup 2/ 2 theta /sub e tau / = 1 at 90% C.L.

  6. The meaning of quality work from the general practitioner's perspective: an interview study

    Directory of Open Access Journals (Sweden)

    Håkansson Anders

    2006-10-01

    Full Text Available Abstract Background The quality of health care and its costs have been a subject of considerable attention and lively discussion. Various methods have been introduced to measure, assess, and improve the quality of health care. Many professionals in health care have criticized quality work and its methods as being unsuitable for health care. The aim of the study was to obtain a deeper understanding of the meaning of quality work from the general practitioner's perspective. Methods Fourteen general practitioners, seven women and seven men, were interviewed with the aid of a semi-structured interview guide about their experience of quality work. The interviews were tape-recorded and transcribed verbatim. Data collection and analysis were guided by a phenomenological approach intended to capture the essence of the statements. Results Two fundamentally different ways to view quality work emerged from the statements: A pronounced top-down perspective with elements of control, and an intra-profession or bottom-up perspective. From the top-down perspective, quality work was described as something that infringes professional freedom. From the bottom-up perspective the statements described quality work as a self-evident duty and as a professional attitude to the medical vocation, guided by the principles of medical ethics. Follow-up with a bottom-up approach is best done in internal processes, with the profession itself designing structures and methods based on its own needs. Conclusions The study indicates that general practitioners view internal follow-up as a professional obligation but external control as an imposition. This opposition entails a difficulty in achieving systematism in follow-up and quality work in health care. If the statutory standards for systematic quality work are to gain a real foothold, they must be packaged in such a way that general practitioners feel that both perspectives can be reconciled.

  7. Pharmacists’ perceptions of their emerging general practice roles in UK primary care: a qualitative interview study

    Science.gov (United States)

    Butterworth, Jo; Sansom, Anna; Sims, Laura; Healey, Mark; Kingsland, Ellie; Campbell, John

    2017-01-01

    Background UK general practice is experiencing a workload crisis. Pharmacists are the third largest healthcare profession in the UK; however, their skills are a currently underutilised and potentially highly valuable resource for primary health care. This study forms part of the evaluation of an innovative training programme for pharmacists who are interested in extended roles in primary care, advocated by a UK collaborative ‘10-point GP workforce action plan’. Aim To explore pharmacists’ perceptions of primary care roles including the potential for greater integration of their profession into general practice. Design and setting A qualitative interview study in UK primary care carried out between October 2015 and July 2016. Method Pharmacists were purposively sampled by level of experience, geographical location, and type of workplace. Two confidential semi-structured telephone interviews were conducted — one before and one after the training programme. A constant comparative, inductive approach to thematic analysis was used. Results Sixteen participants were interviewed. The themes related to: initial expectations of the general practice role, varying by participants’ experience of primary care; the influence of the training course with respect to managing uncertainty, critical appraisal skills, and confidence for the role; and predictions for the future of this role. Conclusion There is enthusiasm and willingness among pharmacists for new, extended roles in primary care, which could effectively relieve GP workload pressures. A definition of the role, with examples of the knowledge, skills, and attributes required, should be made available to pharmacists, primary care teams, and the public. Training should include clinical skills teaching, set in context through exposure to general practice, and delivered motivationally by primary care practitioners. PMID:28673959

  8. Glutathione S-transferase genotypes modify lung function decline in the general population: SAPALDIA cohort study

    Directory of Open Access Journals (Sweden)

    Ackermann-Liebrich Ursula

    2007-01-01

    Full Text Available Abstract Background Understanding the environmental and genetic risk factors of accelerated lung function decline in the general population is a first step in a prevention strategy against the worldwide increasing respiratory pathology of chronic obstructive pulmonary disease (COPD. Deficiency in antioxidative and detoxifying Glutathione S-transferase (GST gene has been associated with poorer lung function in children, smokers and patients with respiratory diseases. In the present study, we assessed whether low activity variants in GST genes are also associated with accelerated lung function decline in the general adult population. Methods We examined with multiple regression analysis the association of polymorphisms in GSTM1, GSTT1 and GSTP1 genes with annual decline in FEV1, FVC, and FEF25–75 during 11 years of follow-up in 4686 subjects of the prospective SAPALDIA cohort representative of the Swiss general population. Effect modification by smoking, gender, bronchial hyperresponisveness and age was studied. Results The associations of GST genotypes with FEV1, FVC, and FEF25–75 were comparable in direction, but most consistent for FEV1. GSTT1 homozygous gene deletion alone or in combination with GSTM1 homozygous gene deletion was associated with excess decline in FEV1 in men, but not women, irrespective of smoking status. The additional mean annual decline in FEV1 in men with GSTT1 and concurrent GSTM1 gene deletion was -8.3 ml/yr (95% confidence interval: -12.6 to -3.9 relative to men without these gene deletions. The GSTT1 effect on the FEV1 decline comparable to the observed difference in FEV1 decline between never and persistent smoking men. Effect modification by gender was statistically significant. Conclusion Our results suggest that genetic GSTT1 deficiency is a prevalent and strong determinant of accelerated lung function decline in the male general population.

  9. Comparison of progressive addition lenses for general purpose and for computer vision: an office field study.

    Science.gov (United States)

    Jaschinski, Wolfgang; König, Mirjam; Mekontso, Tiofil M; Ohlendorf, Arne; Welscher, Monique

    2015-05-01

    Two types of progressive addition lenses (PALs) were compared in an office field study: 1. General purpose PALs with continuous clear vision between infinity and near reading distances and 2. Computer vision PALs with a wider zone of clear vision at the monitor and in near vision but no clear distance vision. Twenty-three presbyopic participants wore each type of lens for two weeks in a double-masked four-week quasi-experimental procedure that included an adaptation phase (Weeks 1 and 2) and a test phase (Weeks 3 and 4). Questionnaires on visual and musculoskeletal conditions as well as preferences regarding the type of lenses were administered. After eight more weeks of free use of the spectacles, the preferences were assessed again. The ergonomic conditions were analysed from photographs. Head inclination when looking at the monitor was significantly lower by 2.3 degrees with the computer vision PALs than with the general purpose PALs. Vision at the monitor was judged significantly better with computer PALs, while distance vision was judged better with general purpose PALs; however, the reported advantage of computer vision PALs differed in extent between participants. Accordingly, 61 per cent of the participants preferred the computer vision PALs, when asked without information about lens design. After full information about lens characteristics and additional eight weeks of free spectacle use, 44 per cent preferred the computer vision PALs. On average, computer vision PALs were rated significantly better with respect to vision at the monitor during the experimental part of the study. In the final forced-choice ratings, approximately half of the participants preferred either the computer vision PAL or the general purpose PAL. Individual factors seem to play a role in this preference and in the rated advantage of computer vision PALs. © 2015 The Authors. Clinical and Experimental Optometry © 2015 Optometry Australia.

  10. A systematic review of studies measuring health-related quality of life of general injury populations

    Directory of Open Access Journals (Sweden)

    Erasmus Vicki

    2010-12-01

    Full Text Available Abstract Background It is important to obtain greater insight into health-related quality of life (HRQL of injury patients in order to document people's pathways to recovery and to quantify the impact of injury on population health over time. We performed a systematic review of studies measuring HRQL in general injury populations with a generic health state measure to summarize existing knowledge. Methods Injury studies (1995-2009 were identified with main inclusion criteria being the use of a generic health status measure and not being restricted to one specific type of injury. Articles were collated by study design, HRQL instrument used, timing of assessment(s, predictive variables and ability to detect change over time. Results Forty one studies met inclusion criteria, using 24 different generic HRQL and functional status measures (most used were SF-36, FIM, GOS, EQ-5D. The majority of the studies used a longitudinal design, but with different lengths and timings of follow-up (mostly 6, 12, and 24 months. Different generic health measures were able to discriminate between the health status of subgroups and picked up changes in health status between discharge and 12 month follow-up. Most studies reported high prevalences of health problems within the first year after injury. The twelve studies that reported HRQL utility scores showed considerable but incomplete recovery in the first year after discharge. Conclusion This systematic review demonstrates large variation in use of HRQL instruments, study populations, and assessment time points used in studies measuring HRQL of general injury populations. This variability impedes comparison of HRQL summary scores between studies and prevented formal meta-analyses aiming to quantify and improve precision of the impact of injury on population health over time.

  11. 78 FR 76855 - Record of Decision for the General Management Plan/Wilderness Study, Fort Pulaski National...

    Science.gov (United States)

    2013-12-19

    ... National Park Service Record of Decision for the General Management Plan/Wilderness Study, Fort Pulaski... (NPS) announces the availability of the Record of Decision (ROD) for the General Management Plan... general management plan process, the National Park Service conducted a wilderness eligibility assessment...

  12. Do patients with unexplained physical symptoms pressurise general practitioners for somatic treatment? A qualitative study

    National Research Council Canada - National Science Library

    Adele Ring; Christopher Dowrick; Gerry Humphris; Peter Salmon

    2004-01-01

    .... Setting 7 general practices in Merseyside, England. Participants 36 patients selected consecutively from 21 general practices, in whom doctors considered that patients' symptoms were medically unexplained...

  13. Barriers among Danish women and general practitioners to raising the issue of intimate partner violence in general practice: a qualitative study

    DEFF Research Database (Denmark)

    Mørk, Trine; Andersen, Pernille Tanggaard; Taket, Ann

    2014-01-01

    Data were collected through individual and group interviews with a sample of three GPs and a diverse sample of 13 women, including both survivors of partner violence and those without any history of partner violence. An interpretative analysis was performed with the data. Results This study provides...... general practitioners to ask about violence in a respectful and non-judgemental manner. However, general practitioners are resistant towards such an inquiry and would benefit from training regarding how to respond to women who have been exposed to IPV. Conclusions It is acceptable to inquire about IPV...... with women in Denmark in a non-judgemental and respectful way. Informing about IPV prevalence is important prior to the inquiry. However, general practitioners require more awareness and training before a favourable environment for this change in procedure can be created. Further large-scale research...

  14. Collaborative care for depression in general practice: study protocol for a randomised controlled trial.

    Science.gov (United States)

    Brinck-Claussen, Ursula Ødum; Curth, Nadja Kehler; Davidsen, Annette Sofie; Mikkelsen, John Hagel; Lau, Marianne Engelbrecht; Lundsteen, Merete; Csillag, Claudio; Christensen, Kaj Sparle; Hjorthøj, Carsten; Nordentoft, Merete; Eplov, Lene Falgaard

    2017-07-21

    Depression is a common illness with great human costs and a significant burden on the public economy. Previous studies have indicated that collaborative care (CC) has a positive effect on symptoms when provided to people with depression, but CC has not yet been applied in a Danish context. We therefore developed a model for CC (the Collabri model) to treat people with depression in general practice in Denmark. Since systematic identification of patients is an "active ingredient" in CC and some literature suggests case finding as the best alternative to standard detection, the two detection methods are examined as part of the study. The aim is to investigate if treatment according to the Collabri model has an effect on depression symptoms when provided to people with depression in general practice in Denmark, and to examine if case finding is a better method to detect depression in general practice than standard detection. The trial is a cluster-randomised, clinical superiority trial investigating the effect of treatment according to the Collabri model for CC, compared to treatment as usual for 480 participants diagnosed with depression in general practice in the Capital Region of Denmark. The primary outcome is depression symptoms (Beck's Depression Inventory (BDI-II)) after 6 months. Secondary outcomes include depression symptoms (BDI-II) after 15 months, anxiety symptoms (Beck's Anxiety Inventory (BAI)), level of functioning (Global Assessment of Function (GAF)) and psychological stress (Symptom Checklist-90-Revised (SCL-90-R)). In addition, case finding (with the recommended screening tool Major Depression Inventory (MDI)) and standard detection of depression is examined in a cluster-randomized controlled design. Here, the primary outcome is the positive predictive value of referral diagnosis. If the Collabri model is shown to be superior to treatment as usual, the study will contribute with important knowledge on how to improve treatment of depression in

  15. A STUDY ON CLINICAL AND AETIOLOGICAL PROFILE OF HEART FAILURE AT KBN TEACHING AND GENERAL HOSPITAL

    Directory of Open Access Journals (Sweden)

    Chandrakala Guruprasad Yelwanti

    2016-10-01

    Full Text Available BACKGROUND The heart failure is a worldwide health problem with ever increasing proportion and is a major health problem in elderly persons. It has many aetiological factors. It is one of the most frequently encountered illnesses in day-to-day practice and most common cause of death in patients with cardiac disease. This study was done to determine the age and sex distribution and to evaluate clinical features and aetiological factors in patients admitted with heart failure at Khaja Banda Nawaz Teaching and General Hospital, Gulbarga, on the basis of clinical assessment, electrocardiography and echocardiography. MATERIALS AND METHODS A prospective study was done in Department of General Medicine at Khaja Banda Nawaz Teaching and General Hospital, Gulbarga, from January 2015 to June 2016 on patients with heart failure to determine the clinical and aetiological profile. A total of 100 cases above the age of 20 years were included in the study. The patients below the age of 20 years and known cases of congenital heart disease were excluded. RESULTS Out of 100 patients, the heart failure was seen more commonly in men than in women between the age groups of 46-65 years of age. Breathlessness was the most common presentation followed by pedal oedema, orthopnoea, etc. In our study, the primary aetiology for heart failure was found to be coronary artery disease (47% followed by dilated cardiomyopathy (20%, hypertension (14%, rheumatic heart disease (7%, anaemia (6%, cor pulmonale (4% and others (2%. Dyslipidaemia was the common risk factor followed by obesity and smoking. CONCLUSION The heart failure commonly occurs in elderly people and the incidence was higher in men than in women. The commonest presentation was breathlessness followed by pedal oedema. The commonest cause of heart failure was coronary artery disease followed by dilated cardiomyopathy and then hypertension combined with ischaemic heart disease.

  16. [Mental health, vulnerability and general practice: a study of non-profit health centers in Grenoble].

    Science.gov (United States)

    Dubois-Fabing, Delphine; Pichon, Philippe; Arnevielhe, Alizée; Suscillon, Marie-Paule; Caron, Bruno; Saillard, Fabienne; François, Patrice

    2011-01-01

    Very little research has been conducted on the role of general practitioners (GPs) in mental health care among socioeconomically disadvantaged populations in France. The non-profit community health care centers in Grenoble provide populations living in sensitive urban zones with high quality primary health care that includes a medico-social and prevention dimension. The aim of this study was to measure the prevalence of mental health issues diagnosed by GPs in health care centers, to identify the factors associated with these issues and to describe treatment characteristics. This cross-sectional study focused on general practice consultations in the AGECSA Grenoble health care centers over the course of one week. At the end of each consultation, the GP collected information about the patient, including personal data, psychological disorders, vulnerability, and patient health management. Among the 451 patients included in the study, GPs found that 45.2% of patients were in vulnerable situations and 43% of patients suffered from a mental disorder, including 29% of cases of anxiety and 20% of cases of depression. 44% of patients suffered from a psychological disorder (mental disorder and/or psychological suffering). For these patients, 52.8% of the consultations lasted more than 20 minutes. Their treatment generally included a mental health care follow-up (in 76% of cases), including psychological support (59%) and treatment of functional somatic disorders (46%). The study shows the high prevalence of psychological disorders diagnosed in the patients treated by GPs working in health care centers in disadvantaged urban areas. Research shows that GPs play an important and specific role in mental health care and prevention. An analysis of the organizational methods used in health care centers is highly relevant.

  17. Characteristics of qualitative studies in influential journals of general medicine: a critical review.

    Science.gov (United States)

    Yamazaki, Hiroshi; Slingsby, Brian Taylor; Takahashi, Miyako; Hayashi, Yoko; Sugimori, Hiroki; Nakayama, Takeo

    2009-12-01

    Although qualitative studies have increased since the 1990s, some reports note that relatively few influential journals published them up until 2000. This study critically reviewed the characteristics of qualitative studies published in top tier medical journals since 2000. We assessed full texts of qualitative studies published between 2000 and 2004 in the Annals of Internal Medicine, BMJ, JAMA, Lancet, and New England Journal of Medicine. We found 80 qualitative studies, of which 73 (91%) were published in BMJ. Only 10 studies (13%) combined qualitative and quantitative methods. Sixty-two studies (78%) used only one method of data collection. Interviews dominated the choice of data collection. The median sample size was 36 (range: 9-383). Thirty-three studies (41%) did not specify the type of analysis used but rather described the analytic process in detail. The rest indicated the mode of data analysis, in which the most prevalent methods were the constant comparative method (23%) and the grounded theory approach (22%). Qualitative data analysis software was used by 33 studies (41%). Among influential journals of general medicine, only BMJ consistently published an average of 15 qualitative study reports between 2000 and 2004. These findings lend insight into what qualities and characteristics make a qualitative study worthy of consideration to be published in an influential journal, primarily BMJ.

  18. Incidence of Awareness with Recall under General Anesthesia in Rural India: An Observational Study.

    Science.gov (United States)

    Singla, Deepak; Mangla, Mishu

    2017-01-01

    Awareness under anesthesia is a rare but extremely unpleasant phenomenon. There are very few studies in the developing world and none from rural areas where incidence of intraoperative awareness may be higher due to increased patient load, limited patient knowledge and lack of trained hospital staff, reliance on older, cheaper but less effective drugs, and lack of proper equipment both for providing anesthesia, as well as monitoring the patient. To assess the incidence of intraoperative awareness during general anesthesia among patients in rural India and any factors associated with the same. Prospective, nonrandomized, observational study. Patients undergoing elective surgical procedures in various specialties under general anesthesia from over a period of 1 year were considered for this study. Approximately, after 1 h of arrival in postanaesthesia care unit, anesthesiologist (not involved in administering anesthesia) assessed intraoperative awareness using a modified form of Brice questionnaire. Data were collected on a Microsoft Excel(®) sheet and analyzed using Statistical Package for the Social Sciences(®) version 23 (SPSS Inc., Chicago, IL, USA) for windows. A total of 896 patients completed the questionnaire. Postoperatively, in response to the questionnaire, seven patients reported to have remembered something under anesthesia. Out of these, three patients described events that were confirmed by operation theater staff to have occurred whereas they were under anesthesia. Incidence of definite awareness under anesthesia with postoperative recall was found to be 0.33% (three patients out of total 896) in our study.

  19. A staff questionnaire study of MRSA infection on ENT and general surgical wards.

    Science.gov (United States)

    Phillips, P S; Golagani, A K; Malik, A; Payne, F B

    2010-09-01

    Methicillin-resistant Staphyloccocus aureus (MRSA) infection has received much attention in both the medical and non-medical press. However, it is not widely encountered on ENT wards, given the profile of short-stay, relatively well patients, although its impact seems to be increasing. We wished to explore the knowledge and attitudes towards MRSA on general surgical and ENT wards, and see if there were any significant differences between specialties, or between doctors and nurses. A 13-item questionnaire with a Likert scale response with six knowledge questions and seven attitude questions was prepared. It was completed anonymously by all nursing and medical staffs on the ENT and general surgical wards of a large District General Hospital. ENT doctors displayed the lowest knowledge and attitude scores; however, this only attained significance in terms of the knowledge of the difference between infection and colonization. Overall, nurses displayed significantly more positive attitudes towards MRSA patients than doctors, but knowledge scores were not significantly different between professions. The study suggests a lack of knowledge about and preponderance of negative attitudes towards MRSA amongst ENT doctors. The difference between colonization and infection is not well understood. Reasons for this may include the relative rarity of MRSA cases on ENT wards.

  20. General and abdominal obesity and incident asthma in adults: the HUNT study.

    Science.gov (United States)

    Brumpton, Ben; Langhammer, Arnulf; Romundstad, Pål; Chen, Yue; Mai, Xiao-Mei

    2013-02-01

    Measures of body mass index (BMI) and waist circumference define general obesity and abdominal obesity respectively. While high BMI has been established as a risk factor for asthma in adults, waist circumference has seldom been investigated. To determine the association between BMI, waist circumference and incident asthma in adults, we conducted a prospective study (n=23,245) in a population living in Nord-Trøndelag, Norway in 1995-2008. Baseline BMI and waist circumference were measured and categorised as general obesity (BMI ≥30.0 kg·m(2)) and abdominal obesity (waist circumference ≥88 cm in females and ≥102 cm in males). Incident asthma was self-reported new-onset cases during an 11-yr follow-up period. Odds ratios for asthma associated with obesity were calculated using multivariable logistic regression. General obesity was a risk factor for asthma in females (OR 1.96, 95% CI 1.52-2.52) and males (OR 1.84, 95% CI 1.30-2.59). In females, after additional adjustment for BMI, abdominal obesity remained a risk factor for asthma development (OR 1.46, 95% CI 1.04-2.05). Abdominal obesity seems to increase the risk of incident asthma in females in addition to BMI, indicating that using both measures of BMI and waist circumference in females may be a superior clinical assessment for asthma risk than any measure alone.

  1. Presentation and treatment of acute maxillary sinusitis in general practice: a French observational study.

    Science.gov (United States)

    Klossek, J M; Mesbah, K

    2011-03-01

    This survey-based study was conducted to determine the characteristics that influence the diagnosis and treatment patterns of acute maxillary sinusitis among general practitioners in France. Questionnaires were sent to 467 physicians and requested to be completed for the next 4 adult (≥ 15 years) patients diagnosed with acute maxillary sinusitis. A total of 397 physicians responded with eligible data on 1585 patients (57.5% female; mean age, 42.3 years). The most common presenting signs and symptoms were moderate-to-severe nasal obstruction (80.4%), pain on sinus palpitation (76.8%), facial pain (74.5%), rhinorrhea (70.4%), and headache (63.6%). Local treatments were prescribed in 93.2% of cases, including nasal lavage (52.1%), vasoconstrictors (42.2%), and intranasal corticosteroids (38.7%). Almost all patients (99%) were prescribed oral treatment including antibiotics (86.5%), analgesics (56.3%), antipyretics (53.7%), and expectorants/mucolytics (45.6%). Symptoms were indicated as having a moderate to very significant effect on quality of life areas including activities of daily living (71.6% of patients), leisure (63.1%), and professional/school activities (59.2%). The diagnosis and management patterns of acute maxillary sinusitis among general practitioners in France are generally consistent with the 2007 European Position Paper on Rhinosinusitis and Nasal Polyps (EP3OS) guidelines.

  2. COMPARATIVE STUDY OF MODIFIED RADICAL MASTECTOMY PERFORMED UNDER LOCAL ANAESTHESIA WITH DEXMEDETOMIDINE INFUSION VS. GENERAL ANAESTHESIA

    Directory of Open Access Journals (Sweden)

    Ramesan Chayampurath

    2016-11-01

    Full Text Available BACKGROUND The incidence of breast cancer is on the rise in developing countries. Though, there have been significant advances in general anaesthesia, surgery in elderly and those with comorbid illness still have an attendant morbidity and mortality. After the introduction of local anaesthesia by Kolher in 1884 and in spite of steady refinement, local anaesthesia is still not being widely used in major general surgical procedures. MATERIALS AND METHODS The study was conducted in Government Medical College, Calicut, a tertiary care centre in Kerala. The outcome of Modified Radical Mastectomy performed under Local Anaesthesia (LA and dexmedetomidine infusion was compared to similar cases done under General Anaesthesia (GA. RESULTS Rapid recovery from sedation leading to early restoration of normal physical activity was observed in the LA group when compared to GA group. Early initiation of oral feeds was possible in the former group as Postoperative Nausea and Vomiting (PONV was significantly less. Effective postoperative pain relief and significant reduction in respiratory complications was observed in the LA group compared to GA group. CONCLUSION Modified Radical Mastectomy under LA and procedural sedation with dexmedetomidine was significantly better in selected cases when compared to similar cases done under GA with respect to early recovery pain relief and decreased incidence of respiratory complications.

  3. Generalized product

    OpenAIRE

    Greco,Salvatore; Mesiar, Radko; Rindone, Fabio

    2014-01-01

    Aggregation functions on [0,1] with annihilator 0 can be seen as a generalized product on [0,1]. We study the generalized product on the bipolar scale [–1,1], stressing the axiomatic point of view. Based on newly introduced bipolar properties, such as the bipolar increasingness, bipolar unit element, bipolar idempotent element, several kinds of generalized bipolar product are introduced and studied. A special stress is put on bipolar semicopulas, bipolar quasi-copulas and bipolar copulas.

  4. Generalized product

    OpenAIRE

    Greco, Salvatore; Mesiar, Radko; Rindone, Fabio

    2014-01-01

    Aggregation functions on [0,1] with annihilator 0 can be seen as a generalized product on [0,1]. We study the generalized product on the bipolar scale [–1,1], stressing the axiomatic point of view. Based on newly introduced bipolar properties, such as the bipolar increasingness, bipolar unit element, bipolar idempotent element, several kinds of generalized bipolar product are introduced and studied. A special stress is put on bipolar semicopulas, bipolar quasi-copulas and bipolar copulas.

  5. On the Study of General Literature%浅论总体文学研究

    Institute of Scientific and Technical Information of China (English)

    郭晓春

    2012-01-01

    For so many years, scholars across the world have been searching for general literary expression which is beyond different nationalities and countries and suitable for all the literature on the earth. Since Goethe and Marx put forward "world literature", general literature, as an important aspect of the field of the study of comparative literature gradually moves into the researchers' horizon. Whereas, as a still controversial conception, general literature encounters great obstacle. So the major task of the article is trying to probe the research content and method of general literature, making some controversies clearer.%寻求一种超越民族、国家的,具有普遍意义的文学表达与理解的思想,一直是不同时代、不同地区的比较文学学者的共同追求。从歌德及马克思等人分别提出“世界文学”的概念起,“总体文学”作为比较文学研究领域的一个重要方面逐渐走入人们的视野。然而,作为在学界仍存在极大争议的“总体文学”,在发展道路上困难重重。因此,对一些有争议的方面进行疏通,确定总体文学的研究内容和方法,为其今后的发展扫清障碍,就成为文章的主要探讨对象。

  6. Introducing undergraduate medical teaching into general practice: an action research study.

    Science.gov (United States)

    Grant, Andy; Robling, Michael

    2006-11-01

    Following the publication of Tomorrow's Doctors and as a result of increasing numbers of students recruited to medical school it is necessary to involve more general practitioners (family physicians) in undergraduate medical education. Students have responded positively regarding experiences in general practices with a broad spectrum of clinical conditions to be seen and greater involvement in clinical decision-making. This action research study followed a small group general practice in South Wales through the required preparation for undergraduate medical education and its first year of teaching. Preparatory work for the practice focused mainly on summarizing patient notes, setting up a practice library and arranging accommodation for the students. Members of the Primary Health Care Team (PHCT) found that having students in the practice gave them a sense of achievement and enhanced self-worth. Individuals within the practice felt more confident in their professional role and the team ethic within the practice was strengthened. Doctors' anxieties regarding the adequacy of their clinical skills proved unfounded. Patients were reported to feel more included in their care and to have enjoyed hearing their condition being discussed with the students. Students valued the one-to-one teaching, seeing common illnesses and a variety of consulting styles. It is hoped that this paper will be of value to those responsible for recruiting GP practices into undergraduate teaching. It demonstrates benefits for the primary health care team in terms of improved morale and sense of professional self-worth. Patients felt more involved in their care. Generalization from these findings is limited by only one practice having been involved. Undergraduate teaching offers advantages, particularly in terms of professional self-esteem and team morale.

  7. Prevalence of Pulmonary Hypertension in the General Population: The Rotterdam Study

    Science.gov (United States)

    Moreira, Eduardo M.; Gall, Henning; Leening, Maarten J. G.; Lahousse, Lies; Loth, Daan W.; Krijthe, Bouwe P.; Kiefte-de Jong, Jessica C.; Brusselle, Guy G.; Hofman, Albert; Stricker, Bruno H.; Ghofrani, Hossein A.; Franco, Oscar H.; Felix, Janine F.

    2015-01-01

    Background Pulmonary hypertension is characterized by increased pulmonary artery pressure and carries an increased mortality. Population-based studies into pulmonary hypertension are scarce and little is known about its prevalence in the general population. We aimed to describe the distribution of echocardiographically-assessed pulmonary artery systolic pressure (ePASP) in the general population, to estimate the prevalence of pulmonary hypertension, and to identify associated factors. Methods Participants (n = 3381, mean age 76.4 years, 59% women) from the Rotterdam Study, a population-based cohort, underwent echocardiography. Echocardiographic pulmonary hypertension was defined as ePASP>40 mmHg. Results Mean ePASP was 26.3 mmHg (SD 7.0). Prevalence of echocardiographic pulmonary hypertension was 2.6% (95%CI: 2.0; 3.2). Prevalence was higher in older participants compared to younger ones (8.3% in those over 85 years versus 0.8% in those between 65 and 70), and in those with underlying disorders versus those without (5.9% in subjects with COPD versus 2.3%; 9.2% in those with left ventricular systolic dysfunction versus 2.3%; 23.1% in stages 3 or 4 left ventricular diastolic dysfunction versus 1.9% in normal or stage 1). Factors independently associated with higher ePASP were older age, higher BMI, left ventricular diastolic dysfunction, COPD and systemic hypertension. Conclusion In this large population-based study, we show that pulmonary hypertension as measured by echocardiography has a low prevalence in the overall general population in the Netherlands, but estimates may be higher in specific subgroups, especially in those with underlying diseases. Increased pulmonary arterial pressure is likely to gain importance in the near future due to population aging and the accompanying prevalences of underlying disorders. PMID:26102085

  8. Prevalence of Pulmonary Hypertension in the General Population: The Rotterdam Study.

    Directory of Open Access Journals (Sweden)

    Eduardo M Moreira

    Full Text Available Pulmonary hypertension is characterized by increased pulmonary artery pressure and carries an increased mortality. Population-based studies into pulmonary hypertension are scarce and little is known about its prevalence in the general population. We aimed to describe the distribution of echocardiographically-assessed pulmonary artery systolic pressure (ePASP in the general population, to estimate the prevalence of pulmonary hypertension, and to identify associated factors.Participants (n = 3381, mean age 76.4 years, 59% women from the Rotterdam Study, a population-based cohort, underwent echocardiography. Echocardiographic pulmonary hypertension was defined as ePASP>40 mmHg.Mean ePASP was 26.3 mmHg (SD 7.0. Prevalence of echocardiographic pulmonary hypertension was 2.6% (95%CI: 2.0; 3.2. Prevalence was higher in older participants compared to younger ones (8.3% in those over 85 years versus 0.8% in those between 65 and 70, and in those with underlying disorders versus those without (5.9% in subjects with COPD versus 2.3%; 9.2% in those with left ventricular systolic dysfunction versus 2.3%; 23.1% in stages 3 or 4 left ventricular diastolic dysfunction versus 1.9% in normal or stage 1. Factors independently associated with higher ePASP were older age, higher BMI, left ventricular diastolic dysfunction, COPD and systemic hypertension.In this large population-based study, we show that pulmonary hypertension as measured by echocardiography has a low prevalence in the overall general population in the Netherlands, but estimates may be higher in specific subgroups, especially in those with underlying diseases. Increased pulmonary arterial pressure is likely to gain importance in the near future due to population aging and the accompanying prevalences of underlying disorders.

  9. A New Insight into the Earthquake Recurrence Studies from the Three-parameter Generalized Exponential Distributions

    Science.gov (United States)

    Pasari, S.; Kundu, D.; Dikshit, O.

    2012-12-01

    Earthquake recurrence interval is one of the important ingredients towards probabilistic seismic hazard assessment (PSHA) for any location. Exponential, gamma, Weibull and lognormal distributions are quite established probability models in this recurrence interval estimation. However, they have certain shortcomings too. Thus, it is imperative to search for some alternative sophisticated distributions. In this paper, we introduce a three-parameter (location, scale and shape) exponentiated exponential distribution and investigate the scope of this distribution as an alternative of the afore-mentioned distributions in earthquake recurrence studies. This distribution is a particular member of the exponentiated Weibull distribution. Despite of its complicated form, it is widely accepted in medical and biological applications. Furthermore, it shares many physical properties with gamma and Weibull family. Unlike gamma distribution, the hazard function of generalized exponential distribution can be easily computed even if the shape parameter is not an integer. To contemplate the plausibility of this model, a complete and homogeneous earthquake catalogue of 20 events (M ≥ 7.0) spanning for the period 1846 to 1995 from North-East Himalayan region (20-32 deg N and 87-100 deg E) has been used. The model parameters are estimated using maximum likelihood estimator (MLE) and method of moment estimator (MOME). No geological or geophysical evidences have been considered in this calculation. The estimated conditional probability reaches quite high after about a decade for an elapsed time of 17 years (i.e. 2012). Moreover, this study shows that the generalized exponential distribution fits the above data events more closely compared to the conventional models and hence it is tentatively concluded that generalized exponential distribution can be effectively considered in earthquake recurrence studies.

  10. Study on the Existence and Uniqueness of Solution of Generalized Capillarity Problem

    Directory of Open Access Journals (Sweden)

    Li Wei

    2012-01-01

    Full Text Available By using the perturbation theories on sums of ranges of nonlinear accretive mappings of Calvert and Gupta (1978, the abstract result on the existence and uniqueness of the solution in Lp(Ω of the generalized Capillarity equation with nonlinear Neumann boundary value conditions, where 2N/(N+1studied. The equation discussed in this paper and the methods here are a continuation of and a complement to the previous corresponding results. To obtain the results, some new techniques are used in this paper.

  11. A General Study on Equivalent Resistance of Three-Terminal Ladder Network

    Institute of Scientific and Technical Information of China (English)

    Wu Guoxiang; Tan Zhizhong; Song Guohua; Song Changqing

    2005-01-01

    In view of the application importance of resistance network in modern science and technology, the author presented the basic structure of a three-terminal ladder shaped resistance network and studied the equivalent resistance of the network. By means of virtual current method, the network was analyzed and a model of two elements three orders differential equation was constructed. Based on different marginal conditions, two general adaptive rules for the inlet resistance of the three-terminal ladder shaped network, as well as two ultimate rules for the equivalent resistance of three-terminal infinite ladder shaped network were given.

  12. A General Study of the Wine Culture in China and the Western World

    Institute of Scientific and Technical Information of China (English)

    WEI Na

    2016-01-01

    Wine culture is considered as an indispensible part of the culture in different countries. Distinctive differences exist be-tween Chinese wine culture and the wine culture in western countries due to their historical backgrounds, different values, cul-tures and customs, etc. A general study of the comparison between Chinese wine culture and western wine culture is given in this paper in order to help us have a better understanding of the wine culture and make us be aware of showing mutual respect for each other.

  13. Barriers among Danish women and general practitioners to raising the issue of intimate partner violence in general practice: a qualitative study

    Science.gov (United States)

    2014-01-01

    Background Thirty-five percent of Danish women experience sexual or physical violence in their lifetime. However, health care professionals are not in the practice of asking about intimate partner violence (IPV) in Denmark. It is currently unknown what hinders general practitioners from asking about partner violence and how Danish women would perceive such an inquiry. This aspect has not previously been explored in Denmark. An exploratory study was conducted to examine what hinders general practitioners (GPs) from asking and what Danish women’s views and attitudes are regarding being asked about IPV. Methods Data were collected through individual and group interviews with a sample of three GPs and a diverse sample of 13 women, including both survivors of partner violence and those without any history of partner violence. An interpretative analysis was performed with the data. Results This study provides important knowledge regarding the barriers and attitudes towards inquiry about IPV in primary care in Denmark. Results indicate that Denmark is facing the same challenges when responding to survivors of IPV as other similar countries, including Sweden, Norway, the UK, USA, and Australia. Danish women want general practitioners to ask about violence in a respectful and non-judgemental manner. However, general practitioners are resistant towards such an inquiry and would benefit from training regarding how to respond to women who have been exposed to IPV. Conclusions It is acceptable to inquire about IPV with women in Denmark in a non-judgemental and respectful way. Informing about IPV prevalence is important prior to the inquiry. However, general practitioners require more awareness and training before a favourable environment for this change in procedure can be created. Further large-scale research is needed to support the evidence generated by this small study. PMID:24893567

  14. Barriers among Danish women and general practitioners to raising the issue of intimate partner violence in general practice: a qualitative study.

    Science.gov (United States)

    Mørk, Trine; Andersen, Pernille Tanggaard; Taket, Ann

    2014-06-03

    Thirty-five percent of Danish women experience sexual or physical violence in their lifetime. However, health care professionals are not in the practice of asking about intimate partner violence (IPV) in Denmark. It is currently unknown what hinders general practitioners from asking about partner violence and how Danish women would perceive such an inquiry. This aspect has not previously been explored in Denmark. An exploratory study was conducted to examine what hinders general practitioners (GPs) from asking and what Danish women's views and attitudes are regarding being asked about IPV. Data were collected through individual and group interviews with a sample of three GPs and a diverse sample of 13 women, including both survivors of partner violence and those without any history of partner violence. An interpretative analysis was performed with the data. This study provides important knowledge regarding the barriers and attitudes towards inquiry about IPV in primary care in Denmark. Results indicate that Denmark is facing the same challenges when responding to survivors of IPV as other similar countries, including Sweden, Norway, the UK, USA, and Australia. Danish women want general practitioners to ask about violence in a respectful and non-judgemental manner. However, general practitioners are resistant towards such an inquiry and would benefit from training regarding how to respond to women who have been exposed to IPV. It is acceptable to inquire about IPV with women in Denmark in a non-judgemental and respectful way. Informing about IPV prevalence is important prior to the inquiry. However, general practitioners require more awareness and training before a favourable environment for this change in procedure can be created. Further large-scale research is needed to support the evidence generated by this small study.

  15. Generalized linear mixed models for multi-reader multi-case studies of diagnostic tests.

    Science.gov (United States)

    Liu, Wei; Pantoja-Galicia, Norberto; Zhang, Bo; Kotz, Richard M; Pennello, Gene; Zhang, Hui; Jacob, Jessie; Zhang, Zhiwei

    2017-06-01

    Diagnostic tests are often compared in multi-reader multi-case (MRMC) studies in which a number of cases (subjects with or without the disease in question) are examined by several readers using all tests to be compared. One of the commonly used methods for analyzing MRMC data is the Obuchowski-Rockette (OR) method, which assumes that the true area under the receiver operating characteristic curve (AUC) for each combination of reader and test follows a linear mixed model with fixed effects for test and random effects for reader and the reader-test interaction. This article proposes generalized linear mixed models which generalize the OR model by incorporating a range-appropriate link function that constrains the true AUCs to the unit interval. The proposed models can be estimated by maximizing a pseudo-likelihood based on the approximate normality of AUC estimates. A Monte Carlo expectation-maximization algorithm can be used to maximize the pseudo-likelihood, and a non-parametric bootstrap procedure can be used for inference. The proposed method is evaluated in a simulation study and applied to an MRMC study of breast cancer detection.

  16. Drug interactions with levothyroxine therapy in patients with hypothyroidism: observational study in general practice.

    Science.gov (United States)

    Trifirò, Gianluca; Parrino, Fabrizio; Sultana, Janet; Giorgianni, Francesco; Ferrajolo, Carmen; Bianchini, Elisa; Medea, Gerardo; Benvenga, Salvatore; Cricelli, Iacopo; Cricelli, Claudio; Lapi, Francesco

    2015-03-01

    Several drugs may interact with levothyroxine and reduce its bioavailability. The aim of this study was to analyse the Italian general practice patients with hypothyroidism from 2002-2011, in terms of variation of thyroid-stimulating hormone (TSH) levels, number of levothyroxine prescriptions and dose of levothyroxine before and during potential drug-drug interactions (DDIs). Data were extracted from the Italian general practice Health Search CSD Longitudinal Patient Database (HSD). Analysis was limited to individuals aged 18 years and older with at least one levothyroxine prescription from 2002 to 2011 and at least one year of clinical history recorded in HSD. A quasi-experimental pre-post analysis was carried out using a self-controlled study design, on an intention-to-treat basis. Overall, 5,426 levothyroxine users (7.5 % of population in HSD) were included in the study. The incidence rate ratio comparing the TSH trend before and during the period of exposure to potential DDI showed a significant increase of TSH levels during initial exposure to potential DDI, which decreased over time. The number of prescriptions and dose of levothyroxine decreased before the potential DDI and increased symmetrically during the period of exposure to potential DDI. The co-prescription of levothyroxine and potentially interacting drugs results in an increased use of levothyroxine. Clinicians should carefully consider adjusting levothyroxine therapy in presence of concomitant drugs, such as proton-pump inhibitors, which may reduce levothyroxine bioavailability.

  17. [Immunization educational game in general practice waiting rooms. A comparative study].

    Science.gov (United States)

    Rolland, Marie-Aude; Gignon, Maxime

    2015-01-01

    The general practitioner’s (GP) waiting room is an ideal place to conduct health education actions. The use of tools in GP waiting rooms would appear to be a useful approach, but the available tools are not very efficient. The objective of this study was to study the efficacy of a game compared with two other health education strategies. A comparative study was conducted in two general practices. 212 patients were divided into three groups using a paper-game or a booklet or nothing in the waiting room, before a discussion about immunization with the practitioner. The capacity of the tool to encourage questions about immunization was estimated by the GP at the end of the consultation by a questionnaire. The use of a tool in the waiting room facilitated the discussion between patients and practitioners (34% vs 12%, pgame induced longer discussions than the booklet (1 minute 32 seconds vs 1 minute 14 seconds, pgame and the booklet had a comparable acceptability. Using a multistep education strategy facilitated discussion between the patient and the practitioner. However, the GP is required to trigger the conversation.

  18. The Generalized Higher Criticism for Testing SNP-Set Effects in Genetic Association Studies.

    Science.gov (United States)

    Barnett, Ian; Mukherjee, Rajarshi; Lin, Xihong

    2017-01-01

    It is of substantial interest to study the effects of genes, genetic pathways, and networks on the risk of complex diseases. These genetic constructs each contain multiple SNPs, which are often correlated and function jointly, and might be large in number. However, only a sparse subset of SNPs in a genetic construct is generally associated with the disease of interest. In this article, we propose the generalized higher criticism (GHC) to test for the association between an SNP set and a disease outcome. The higher criticism is a test traditionally used in high-dimensional signal detection settings when marginal test statistics are independent and the number of parameters is very large. However, these assumptions do not always hold in genetic association studies, due to linkage disequilibrium among SNPs and the finite number of SNPs in an SNP set in each genetic construct. The proposed GHC overcomes the limitations of the higher criticism by allowing for arbitrary correlation structures among the SNPs in an SNP-set, while performing accurate analytic p-value calculations for any finite number of SNPs in the SNP-set. We obtain the detection boundary of the GHC test. We compared empirically using simulations the power of the GHC method with existing SNP-set tests over a range of genetic regions with varied correlation structures and signal sparsity. We apply the proposed methods to analyze the CGEM breast cancer genome-wide association study. Supplementary materials for this article are available online.

  19. Prospective study of use of perioperative antimicrobial therapy in general surgery.

    LENUS (Irish Health Repository)

    Fennessy, Brendan G

    2012-02-03

    BACKGROUND: Perioperative antimicrobial therapy has demonstrated efficacy in reducing the rate of surgical site infections in clinical trials. With the emergence of antibiotic resistance, the risk of reaction, and the inevitable financial repercussions, use of prophylactic antibiotics is not a panacea, and their misuse may have considerable implications. The aim of this study was to assess the use of antibiotics in the perioperative period in both general and vascular surgery procedures. METHODS: A prospective study was undertaken of 131 patients with a mean age of 43 years (range one month-88 years), of whom 68 (51%) were male, who underwent twenty-seven different general or vascular surgery procedures over a four-week period. Each patient was evaluated from the time of antibiotic commencement through their operative procedure until the treatment was discontinued. RESULTS: A total of 73 patients (54%) received ten antibiotics, with 71 (97%) of these uses being prophylactic. Of the 15 appendectomies performed for uncomplicated appendicitis, the mean number of prophylactic antibiotic doses was 5.3 (range 1-12). Where they were documented, written postoperative directives were not adhered to in 18\\/27 prescriptions (66%). CONCLUSION: This study has demonstrated a lack of adherence to guidelines in the perioperative administration of antimicrobial agents. In addition, it calls attention to the economic implications of unnecessary prophylaxis.

  20. 78 FR 67187 - Notice of Availability of the Draft General Management Plan/Wilderness Study/Environmental Impact...

    Science.gov (United States)

    2013-11-08

    ... National Park Service Notice of Availability of the Draft General Management Plan/ Wilderness Study... availability of the Draft General Management Plan/Wilderness Study/Environmental Impact Statement (GMP/WS/EIS... for evaluating the action alternatives. The NPS would maintain the Big Spring Wilderness Study...

  1. The Rationale and Challenge for the Integration of Science Studies in the Revision of General Education Curricula

    Science.gov (United States)

    Hammer, Christy; Dusek, Val

    2006-01-01

    A broadened view of scientific literacy for general education revision is detailed, including the history, philosophy, and sociology of science and science and technology studies. We provide a case study from an interdisciplinary college, argue for the integration of science studies into general education curricula, and discuss barriers to success.

  2. Index of /data/h-inv/LATEST [Life Science Database Archive metadata

    Lifescience Database Archive (English)

    Full Text Available Index of /data/h-inv/LATEST Name Last modified Size Description Parent Directory - ...ml 17-Aug-2016 11:40 9.5K acc2hinv_id.txt.gz 25-May-2015 12:04 3.0M Index of /data/h-inv/LATEST ...

  3. The latest results from DICE (Detector Interferometric Calibration Experiment)

    Science.gov (United States)

    Crouzier, A.; Malbet, F.; Hénault, F.; Léger, A.; Cara, C.; Le Duigou, J. M.; Preis, O.; Kern, P.; Delboulbe, A.; Martin, G.; Feautrier, P.; Stadler, E.; Lafrasse, S.; Rochat, S.; Ketchazo, C.; Donati, M.; Doumayrou, Eric; Lagage, P. O.; Shao, M.; Goullioud, R.; Nemati, B.; Zhai, C.; Behar, E.; Potin, S.; Saint-Pe, M.; Dupont, J.

    2016-07-01

    Theia is an astrometric mission proposed to ESA in 2014 for which one of the scientific objectives is detecting Earth-like exoplanets in the habitable zone of nearby solar-type stars. This objective requires the capability to measure stellar centroids at the precision of 1x10-5 pixel. Current state-of-the-art methods for centroid estimation have reached a precision of about 3x10-5 pixel at two times Nyquist sampling, this was shown at the JPL by the VESTA experiment. A metrology system was used to calibrate intra and inter pixel quantum efficiency variations in order to correct pixelation errors. The Theia consortium is operating a testbed in vacuum in order to achieve 1x10-5 pixel precision for the centroid estimation. The goal is to provide a proof of concept for the precision requirement of the Theia spacecraft. The testbed consists of two main sub-systems. The first one produces pseudo stars: a blackbody source is fed into a large core fiber and lights-up a pinhole mask in the object plane, which is imaged by a mirror on the CCD. The second sub-system is the metrology, it projects young fringes on the CCD. The fringes are created by two single mode fibers facing the CCD and fixed on the mirror. In this paper we present the latest experiments conducted and the results obtained after a series of upgrades on the testbed was completed. The calibration system yielded the pixel positions to an accuracy estimated at 4x10-4 pixel. After including the pixel position information, an astrometric accuracy of 6 x 10-5 pixel was obtained, for a PSF motion over more than 5 pixels. In the static mode (small jitter motion of less than 1 x 10-3 pixel), a photon noise limited precision of 3x10-5 pixel was reached.

  4. Chronic disease management in general practice: results from a national study.

    LENUS (Irish Health Repository)

    Darker, C

    2012-04-01

    The aim of this study was to provide baseline data on chronic disease management (CDM) provision in Irish general practice (GP). The survey instrument was previously used in a study of primary care physicians in 11 countries, thus allowing international comparisons. The response rate was 72% (380\\/527).The majority of GPs (240\\/380; 63%) reported significant changes are needed in our health care system to make CDM work better. Small numbers of routine clinical audits are being performed (95\\/380; 25%). Irish GPs use evidence based guidelines for treatment of diabetes (267\\/380; 71%), asthma \\/ COPD (279\\/380; 74%) and hypertension (297\\/380; 79%), to the same extent as international counterparts. Barriers to delivering chronic care include increased workload (379\\/380; 99%), lack of appropriate funding (286\\/380; 76%), with GPs interested in targeted payments (244\\/380; 68%). This study provides baseline data to assess future changes in CDM.

  5. Developing COPD: a 25 year follow up study of the general population

    DEFF Research Database (Denmark)

    Løkke, Anders; Lange, Peter; Scharling, H;

    2006-01-01

    population. METHODS: As part of the Copenhagen City Heart Study, 8045 men and women aged 30-60 years with normal lung function at baseline were followed for 25 years. Lung function measurements were collected and mortality from COPD during the 25 year observation period was analysed. RESULTS: The percentage......BACKGROUND: Smokers are more prone to develop chronic obstructive pulmonary disease (COPD) than non-smokers, but this finding comes from studies spanning 10 years or less. The aim of this study was to determine the 25 year absolute risk of developing COPD in men and women from the general...... cessation, especially early in the follow up period, decreased the risk of developing COPD substantially compared with continuous smoking. During the follow up period there were 2912 deaths, 109 of which were from COPD. 92% of the COPD deaths occurred in subjects who were current smokers at the beginning...

  6. E-Commerce Adoption at Customer Level in Jordan: an Empirical Study of Philadelphia General Supplies

    Directory of Open Access Journals (Sweden)

    Mohammed Al Masarweh

    2016-11-01

    Full Text Available E-commerce in developing countries has been studied by numerous researchers during the last decade and a number of common and culturally specific challenges have been identified.. This study considers Jordan as a case study of a developing country where E-commerce is still in its infancy. Therefore, this research work comes as a complement to previous research and an opportunity to refine E-commerce adaptation research. This research was conducted by survey distributed randomly across branches of Philadelphia General Supplies (PGS, a small and medium enterprise (SME. The key findings in this research indicated that Jordanian society is moving towards online shopping at very low rates of adoption, due to barriers including weak infrastructure throughout the country except in the capital, societal trends and culture and educational and computer literacy. This means that E-commerce in Jordan still remains an under-developed industry.

  7. Burnout, empathy and their relationships: a qualitative study with residents in General Medicine.

    Science.gov (United States)

    Picard, Jeanne; Catu-Pinault, Annie; Boujut, Emilie; Botella, Marion; Jaury, Philippe; Zenasni, Franck

    2016-01-01

    Some studies have shown that burnout may have a negative impact on clinical empathy during internship. However, clinical empathy may also be a protective factor, preventing residents from experiencing burnout. Although several quantitative studies have been conducted to examine these relationships between burnout and empathy, no qualitative studies have been carried out. To examine how residents in general practice evaluate the link between burnout and empathy, 24 of them participated in a semi-structured interview. A thematic analysis was carried out to examine residents' discourses and answers to closed questions. The results indicated that residents thought that empathy and burnout were clearly related in different ways. They identified five types of relationship: regulation strategy, empathy as protection, psychological balance/imbalance, fatigue and moderating factors.

  8. Neuropathic pain in the general population: a systematic review of epidemiological studies.

    Science.gov (United States)

    van Hecke, O; Austin, Sophie K; Khan, Rafi A; Smith, B H; Torrance, N

    2014-04-01

    Most patients with neuropathic pain symptoms present and are managed in primary care, with only a minority being referred for specialist clinical assessment and diagnoses. Previous reviews have focused mainly on specific neuropathic pain conditions based in specialist settings. This is the first systematic review of epidemiological studies of neuropathic pain in the general population. Electronic databases were searched from January 1966 to December 2012, and studies were included where the main focus was on neuropathic pain prevalence and/or incidence, either as part of a specific neuropathic pain-related condition or as a global entity in the general population. We excluded studies in which data were extracted from pain or other specialist clinics or focusing on specific population subgroups. Twenty-one articles were identified and underwent quality assessment and data extraction. Included studies differed in 3 main ways: method of data retrieval, case ascertainment tool used, and presentation of prevalence/incidence rates. This heterogeneity precluded any meta-analysis. We categorised comparable incidence and prevalence rates into 2 main subgroups: (1) chronic pain with neuropathic characteristics (range 3-17%), and (2) neuropathic pain associated with a specific condition, including postherpetic neuralgia (3.9-42.0/100,000 person-years [PY]), trigeminal neuralgia (12.6-28.9/100,000 PY), painful diabetic peripheral neuropathy (15.3-72.3/100,000 PY), glossopharyngeal neuralgia (0.2-0.4/100,000 PY). These differences highlight the importance of a standardised approach for identifying neuropathic pain in future epidemiological studies. A best estimate of population prevalence of pain with neuropathic characteristics is likely to lie between 6.9% and 10%. Copyright © 2013 International Association for the Study of Pain. Published by Elsevier B.V. All rights reserved.

  9. erception of Technical Education Students on the Role of ICT in General Studies Programme (GSP In University Education

    Directory of Open Access Journals (Sweden)

    E. Kennedy Umunadi

    2011-10-01

    Full Text Available The role of Information and Communication Technology (ICT in teaching and learning is rapidly becoming one of the most important widely discussed issues in contemporary general studies programme in university education. The paper examined the perception of technical education students on the role of information and communication technology in general studies programme in Nigeria. The paper discussed National Policy for Information and Communication Technology, the role of ICT in general studies in university education, general studies in university education, university education policies, and approaches to ICT integration in general studies. The study made use of questionnaire as instrument of the study. The population of the study was 48 students in technical education unit of technical and business education department, Delta State University, Abraka. The students attested that some of the ICT facilities are available but not properly utilized in learning general studies in the university. The findings also revealed that there is a significant difference in the perception of students on the extent of availability and utilization of ICT facilities in learning general studies. It was based on these findings that the researcher recommended that general studies should be equipped with ICT facilities to facilitate learning in technical education field among others.

  10. Promoting chlamydia screening with posters and leaflets in general practice - a qualitative study

    Directory of Open Access Journals (Sweden)

    Ford-Young William

    2009-10-01

    Full Text Available Abstract Background General practice staff are reluctant to discuss sexual health opportunistically in all consultations. Health promotion materials may help alleviate this barrier. Chlamydia screening promotion posters and leaflets, produced by the English National Chlamydia Screening Programme (NCSP, have been available to general practices, through local chlamydia screening offices, since its launch. In this study we explored the attitudes of general practice staff to these screening promotional materials, how they used them, and explored other promotional strategies to encourage chlamydia screening. Methods Twenty-five general practices with a range of screening rates, were purposively selected from six NCSP areas in England. In focus groups doctors, nurses, administrative staff and receptionists were encouraged to discuss candidly their experiences about their use and opinions of posters, leaflets and advertising to promote chlamydia screening. Researchers observed whether posters and leaflets were on display in reception and/or waiting areas. Data were collected and analysed concurrently using a stepwise framework analytical approach. Results Although two-thirds of screening practices reported that they displayed posters and leaflets, they were not prominently displayed in most practices. Only a minority of practices reported actively using screening promotional materials on an ongoing basis. Most staff in all practices were not following up the advertising in posters and leaflets by routinely offering opportunistic screening to their target population. Some staff in many practices thought posters and leaflets would cause offence or embarrassment to their patients. Distribution of chlamydia leaflets by receptionists was thought to be inappropriate by some practices, as they thought patients would be offended when being offered a leaflet in a public area. Practice staff suggested the development of pocket-sized leaflets. Conclusion The NCSP

  11. Latest Early Pleistocene remains of Lynx pardinus (Carnivora, Felidae) from the Iberian Peninsula: Taxonomy and evolutionary implications

    Science.gov (United States)

    Boscaini, Alberto; Alba, David M.; Beltrán, Juan F.; Moyà-Solà, Salvador; Madurell-Malapeira, Joan

    2016-07-01

    The Iberian lynx (Lynx pardinus) is a critically endangered felid that, during the last fifty years, has been subject to an intensive conservation program in an attempt to save it from extinction. This species is first recorded at ca. 1.7-1.6 Ma (late Villafranchian, late Early Pleistocene) in NE Iberian Peninsula, roughly coinciding with the large faunal turnover that occurred around the middle to late Villafranchian boundary. Here we describe the largest collection of L. pardinus remains available to date from the Iberian late Early Pleistocene (Epivillafranchian), including localities from the Vallparadís Section (Vallès-Penedès Basin, NE Iberian Peninsula) and Cueva Victoria (Cartagena, SE Iberian Peninsula). The morphology and biometry of the studied material attests to the widespread occurrence of L. pardinus in the Mediterranean coast of the Iberian Peninsula since the latest Early Pleistocene, i.e., about 0.5 million years earlier than it was generally accepted (i.e., at the beginning of the Middle Pleistocene). Based on the features observed in the large sample studied in this paper, we conclude that Lynx spelaeus is a junior synonym of L. pardinus and further propose to assign all the Epivillafranchian and younger fossil lynxes from SW Europe to the extant species L. pardinus. Due to the arrival of the Eurasian lynx (Lynx lynx) into Europe at the beginning of the Late Pleistocene, the attribution of specimens younger than MIS 5e to either this species or L. pardinus solely on morphological grounds has proven equivocal. Here we discuss the main diagnostic features of both species of European lynxes and further review their evolutionary history and paleobiogeography throughout the Pleistocene.

  12. Techniques and Behaviors Associated with Exemplary Inpatient General Medicine Teaching: An Exploratory Qualitative Study.

    Science.gov (United States)

    Houchens, Nathan; Harrod, Molly; Moody, Stephanie; Fowler, Karen; Saint, Sanjay

    2017-07-01

    Clinician educators face numerous obstacles to their joint mission of facilitating high-quality learning while also delivering patient-centered care. Such challenges necessitate increased attention to the work of exemplary clinician educators, their respective teaching approaches, and the experiences of their learners. To describe techniques and behaviors utilized by clinician educators to facilitate excellent teaching during inpatient general medicine rounds. An exploratory qualitative study of inpatient teaching conducted from 2014 to 2015. Inpatient general medicine wards in 11 US hospitals, including university-affiliated hospitals and Veterans Affairs medical centers. Participants included 12 exemplary clinician educators, 57 of their current learners, and 26 of their former learners. In-depth, semi-structured interviews of exemplary clinician educators, focus group discussions with their current and former learners, and direct observations of clinical teaching during inpatient rounds. Interview data, focus group data, and observational field notes were coded and categorized into broad, overlapping themes. Each theme elucidated a series of actions, behaviors, and approaches that exemplary clinician educators consistently demonstrated during inpatient rounds: (1) they fostered positive relationships with all team members by building rapport, which in turn created a safe learning environment; (2) they facilitated patient-centered teaching points, modeled excellent clinical exam and communication techniques, and treated patients as partners in their care; and (3) they engaged in coaching and collaboration through facilitation of discussion, effective questioning strategies, and differentiation of learning among team members with varied experience levels. This study identified consistent techniques and behaviors of excellent teaching during inpatient general medicine rounds.

  13. A prospective study of the modified Atkins diet for adults with idiopathic generalized epilepsy.

    Science.gov (United States)

    Kverneland, Magnhild; Selmer, Kaja K; Nakken, Karl O; Iversen, Per O; Taubøll, Erik

    2015-12-01

    For children with pharmacoresistant epilepsy, the ketogenic diet is an established treatment option worldwide. However, for adults, this treatment is less frequently offered, and its efficacy less well-documented. The aim of this study was to examine efficacy and tolerability of such a diet as an adjuvant therapy to antiepileptic drugs for adult patients with pharmacoresistant generalized epilepsy. Thirteen patients (12 women) aged 16-57 years were included prospectively. They were treated with a modified Atkins diet for 12 weeks. Nine of the 13 participants had juvenile myoclonic epilepsy (JME), two had childhood absence epilepsy, one had Jeavons syndrome, and one had generalized epilepsy of unknown type. Six participants, all with JME, completed the 12-week study period. Among these six, four had >50% seizure reduction. Their seizure severity, using the revised Liverpool Seizure Severity Scale, was reduced by 1, 5, 57.5, and 70 points, respectively (scale: 1-100 points). In three of these four responders, quality of life, assessed by QOLIE-89, increased more than 20 points (scale: 0-100 points). Mean reduction of body weight after 12 weeks on diet was 6.5 (range: 4.3-8.1) kg. Lack of motivation, poor compliance, and seizure aggravation were the main reasons for premature termination of the diet. Apart from one patient who developed gallstones when ending the treatment after 10 months, no adverse effects were noted. In conclusion, using a modified Atkins diet for 12 weeks led to a clinically relevant reduction of seizure frequency in four of thirteen adult patients with pharmacoresistant generalized epilepsy. All responders were diagnosed with JME. In three of the four, the benefits of diet were so considerable that they chose to continue the treatment.

  14. General practitioners' views on reattribution for patients with medically unexplained symptoms: a questionnaire and qualitative study

    Directory of Open Access Journals (Sweden)

    Salmon Peter

    2008-08-01

    Full Text Available Abstract Background The successful introduction of new methods for managing medically unexplained symptoms in primary care is dependent to a large degree on the attitudes, experiences and expectations of practitioners. As part of an exploratory randomised controlled trial of reattribution training, we sought the views of participating practitioners on patients with medically unexplained symptoms, and on the value of and barriers to the implementation of reattribution in practice. Methods A nested attitudinal survey and qualitative study in sixteen primary care teams in north-west England. All practitioners participating in the trial (n = 74 were invited to complete a structured survey. Semi-structured interviews were undertaken with a purposive sub-sample of survey respondents, using a structured topic guide. Interview transcripts were used to identify key issues, concepts and themes, which were grouped to construct a conceptual framework: this framework was applied systematically to the data. Results Seventy (95% of study participants responded to the survey. Survey respondents often found it stressful to work with patients with medically unexplained symptoms, though those who had received reattribution training were more optimistic about their ability to help them. Interview participants trained in reattribution (n = 12 reported that reattribution increased their confidence to practice in a difficult area, with heightened awareness, altered perceptions of these patients, improved opportunities for team-building and transferable skills. However general practitioners also reported potential barriers to the implementation of reattribution in routine clinical practice, at the level of the patient, the doctor, the consultation, diagnosis and the healthcare context. Conclusion Reattribution training increases practitioners' sense of competence in managing patients with medically unexplained symptoms. However, barriers to its implementation are

  15. General surgeon's antibiotic stewardship: Climbing the Rogers Diffusion of Innovation Curve-Prospective Cohort Study.

    Science.gov (United States)

    Rizan, Chantelle; Phee, Jaewon; Boardman, Charlotte; Khera, Goldie

    2017-04-01

    The primary aim of this study was to establish concordance of general surgeon's prescribing practice with local IV-oral antibiotic guidelines. The secondary aim was to evaluate the effect of introducing educational antibiotic measures. The Rogers Diffusion of Innovation Model was used to explore the adoption of antibiotic stewardship practices. In this prospective, cohort study, data was collected on 100 pre and 100 post awareness intervention programme patients. The educational intervention comprised raising awareness of a) the guidelines b) pre-intervention results c) introducing an IV-oral antibiotic prompt sheet. The concordance with local guidelines was compared between pre- and post-intervention groups using Fisher's Exact Test or Pearson's Chi Test (SPSS Statistics V22). The concordance of general surgical doctors with local IV-oral antibiotic guidelines was poor and did not improve significantly following the awareness intervention programme. There was no uptake of the antibiotic prompt sheet. There was a trend towards increase in the number of patients switched from IV to oral antibiotics at 48-72 h and significant increase (p review IV antibiotics. Antibiotic governance measures failed to inspire even an initial group of innovators to use the antibiotic prompt sheets. It appears educational measures are effective in improving prescribing behavior and intent amongst a group of early adopters, but this fails to reach a critical mass. In order to improve antibiotic governance and embark upon the Rogers Diffusion of Innovation Curve, more must be done to engage general surgical doctors in timely, judicious antibiotic prescribing. Copyright © 2017 IJS Publishing Group Ltd. Published by Elsevier Ltd. All rights reserved.

  16. CLINICAL STUDY ON PA NCREATIC CANCER IN G OVERNMENT GENERAL HOSPITAL, GU NTUR, AP, INDIA

    Directory of Open Access Journals (Sweden)

    Ch. Kalyan

    2015-03-01

    Full Text Available Pancreatic cancer has a lower incidence than many other types of cancer, but is the fourth most common cause of death from cancer, among men and women, being responsible for 6% of all cancer - related deaths. The global annual incidence rate for pancreas cancer is about 8/100,000 persons. Pancreatic cancer disease is notoriously difficult to diagnose in its early stages. Study was carried out in the Department of General Surgery, Government General Hospital, Guntur from October 2010 to 2012, in which 16 cases with a diagnosis of carcinoma pancreas. They were investigated with routine blood investigations. They were treated accordingly with Pylorus preserving pancreaticodenectomy (PPPD or palliative bypass or with non - operative palliative measures. Carcinoma pancreas is an aggressive disease with male preponderance with peak incidence in 5th and 6th decade. Important risk factors are Smoking and alcohol consumption. Nearly 75% of the cases presented in the late stage of the disease. Resection of the tumour had better survival. The limitations of our study are small number of patients and short follow - up

  17. A comparative study of six decades of general science textbooks: Evaluating the evolution of science content

    Science.gov (United States)

    Lewis, Anna

    This study examined science textbooks over time to better understand the science content expectations that the U.S. educational system deems appropriate for 8th and 9th grade science students. The study attempted to answer the questions: (1) What specific science content has been presented via the textbook from 1952 to 2008? (2) Within which areas and in what way does the science content change? (3) Are new scientific findings reflected in 8th and 9th grade U.S. general science textbooks? Twenty-six themes were identified which reflect five areas in science: Chemistry, Physics, Earth Science, Biology, and Process of Science. Trends in science content in U.S. 8th and 9th grade general science textbooks, as revealed by this data sample, indicated no statistically significant change in depth of coverage in Physics and Process of Science over the past 60 years, no significant change in depth of coverage in Earth Science and Biology in the last 40 years, and no significant change in coverage in Chemistry over the last 30 years. Additionally, a total of sixteen new discoveries were found in the textbook sample. For classroom teachers this information may alert them to the necessity of going beyond the textbook in preparing students for life in a global society. In educational practice, this research supports and reinforces the need for inquiry learning and socioscientific curricula. It may also influence educators to challenge assumptions regarding the value and selection of the traditional classic science content.

  18. Prospective effect of job strain on general and central obesity in the Whitehall II Study.

    Science.gov (United States)

    Brunner, Eric J; Chandola, Tarani; Marmot, Michael G

    2007-04-01

    Positive energy balance is the major cause of obesity, and chronic stress may be a contributory factor. The authors examined cumulative work stress, using the Job Strain Questionnaire on four occasions, as a predictor of obesity in a prospective 19-year study of 6,895 men and 3,413 women (aged 35-55 years) in the Whitehall II cohort in London, United Kingdom (baseline: 1985-1988). A dose-response relation was found between work stress and risk of general obesity (body mass index > or =30 kg/m(2)) and central obesity (waist circumference >102 cm in men, >88 cm in women) that was largely independent of covariates. The imputed odds ratios of body mass index obesity for one, two, and three or more reports of work stress adjusted for age, sex, and social position were 1.17, 1.24, and 1.73 (trend p < 0.01), respectively. For waist obesity, the corresponding findings were 1.17, 1.41, and 1.61 (trend p < 0.01). Work stress effect was modestly attenuated after exclusion of obese individuals at baseline and further adjustments for smoking; intakes of dietary fiber, fruits and vegetables, and alcohol; and levels of physical activity during follow-up. This study provides prospective, population-based evidence that chronic work stress predicts general and central obesity.

  19. Regulatory forum opinion piece: blind reading of histopathology slides in general toxicology studies.

    Science.gov (United States)

    Neef, Natasha; Nikula, Kristen J; Francke-Carroll, Sabine; Boone, Laura

    2012-06-01

    With the intention of reducing bias, a recent European Food Safety Authority draft guidance document included a recommendation for blinded evaluation of histopathology slides in general toxicology studies (EFSA 2011). Although blinding as to treatment status reduces bias in many types of scientific experiment and is sometimes also appropriate in toxicologic pathology (Holland and Holland 2011), it is most unlikely to help achieve the overall goal of improved human safety when used for routine histopathology evaluation of tissues in general toxicology studies. This is the case because (1) blinding is not applicable to the inductive reasoning process used to identify test article effects in the tissues and would dramatically reduce the chances of these being successfully identified; and (2) in any case, the bias that would be reduced by blinding is actually a bias favoring diagnosis of a toxicological hazard and a conservative safety evaluation, which is appropriate in this context. Other unintended consequences of blinding histopathology evaluation include reductions in sensitivity for a variety of additional reasons and increased subjectivity of the pathology data.

  20. Generalized ensemble method applied to study systems with strong first order transitions

    Science.gov (United States)

    Małolepsza, E.; Kim, J.; Keyes, T.

    2015-09-01

    At strong first-order phase transitions, the entropy versus energy or, at constant pressure, enthalpy, exhibits convex behavior, and the statistical temperature curve correspondingly exhibits an S-loop or back-bending. In the canonical and isothermal-isobaric ensembles, with temperature as the control variable, the probability density functions become bimodal with peaks localized outside of the S-loop region. Inside, states are unstable, and as a result simulation of equilibrium phase coexistence becomes impossible. To overcome this problem, a method was proposed by Kim, Keyes and Straub [1], where optimally designed generalized ensemble sampling was combined with replica exchange, and denoted generalized replica exchange method (gREM). This new technique uses parametrized effective sampling weights that lead to a unimodal energy distribution, transforming unstable states into stable ones. In the present study, the gREM, originally developed as a Monte Carlo algorithm, was implemented to work with molecular dynamics in an isobaric ensemble and coded into LAMMPS, a highly optimized open source molecular simulation package. The method is illustrated in a study of the very strong solid/liquid transition in water.

  1. [General pharmacological studies on human natural tumor necrosis factor (MHR-24)].

    Science.gov (United States)

    Sato, M; Imada, K; Iida, S; Ohashi, K; Kimura, S; Niho, T

    1993-04-01

    The general pharmacological properties of MHR-24 were studied in various experimental animals. Intravenously (i.v.)-administered MHR-24 at 8.6 x 10(2) JRU/kg or more produced fever in rabbits. MHR-24 at 3 x 10(4) JRU/kg or more caused tachycardia; and at 1 x 10(5) JRU/kg or more, it lowered arterial blood pressure in anesthetized monkeys. In rats, MHR-24 at 2.9 x 10(4) JRU/kg or more showed a diuretic action and inhibitory effects on gastric juice secretion and carrageenin-induced paw edema. Furthermore, MHR-24 at a large dose (8.6 x 10(4) or 2.9 x 10(5) JRU/kg, i.v.) decreased spontaneous locomotor activity, had an inhibitory effect on acetic acid-induced writhing and potentiated intestinal propulsion in mice; and it caused the appearance of rest wave on acute spontaneous electroencephalograms in rabbits. Pretreatment of the animals with the cyclooxygenase inhibitor indomethacin abolished the fever and potentiation of intestinal propulsion caused by MHR-24. Therefore, these data seem to indicate that some of the effects of MHR-24 are mediated via cyclooxygenase pathways. The results suggested that, except for the above results, MHR-24 has no noticeable effects on the central nervous, autonomic nervous, respiratory and cardiovascular systems and others in general pharmacological studies.

  2. General practitioners' perspective on poverty: a qualitative study in Montreal, Canada.

    Science.gov (United States)

    Loignon, Christine; Gottin, Thomas; Dupéré, Sophie; Bedos, Christophe

    2017-08-24

    Social inequalities in healthcare systems persist worldwide. Physicians' prejudices and negative attitudes towards people living in poverty are one of the determinants of healthcare inequalities. We know very little about general practitioners' (GPs) perceptions of poverty, which shape their attitudes. To identify the perceptions of poverty of GPs who deal with it in everyday practice. A qualitative study based on interviews with GPs working in deprived urban neighbourhoods. In-depth semi-structured interviews were conducted with physicians working in disadvantaged neighbourhoods in Montreal, Canada. Interviews were audio-recorded and transcribed verbatim. Analysis consisted of interview debriefing, transcript coding, and thematic analysis using an inductive and iterative approach. Our study revealed two contrasting perceptions of poverty. The global conception of poverty referred to social determinants and was shared by the majority of physicians interviewed, while the moral conception, centring on individual responsibility, was shared by a minority of participants. The moral judgments and misunderstandings evidenced by GPs regarding poverty suggest avenues for improving general medical training. Understanding social determinants of health should be an important component of this training, to improve access to care for people living in poverty.

  3. Prediction of depression in European general practice attendees: the PREDICT study

    Directory of Open Access Journals (Sweden)

    Geerlings Mirjam I

    2006-01-01

    Full Text Available Abstract Background Prevention of depression must address multiple risk factors. Estimating overall risk across a range of putative risk factors is fundamental to prevention of depression. However, we lack reliable and valid methods of risk estimation. This protocol paper introduces PREDICT, an international research study to address this risk estimation. Methods/design This is a prospective study in which consecutive general practice attendees in six European countries are recruited and followed up after six and 12 months. Prevalence of depression is assessed at baseline and each follow-up point. Consecutive attendees between April 2003 and September 2004 who were aged 18 to 75 were asked to take part. The possibility of a depressive episode was assessed using the Depression Section of the Composite International Diagnostic Interview. A selection of presumed risk factors was based on our previous work and a systematic review of the literature. It was necessary to evaluate the test-retest reliability of a number of risk factor questions that were developed specifically, or adapted, for the PREDICT study. In a separate reliability study conducted between January and November 2003, consecutive general practice attendees in the six participating European countries completed the risk factor items on two occasions, two weeks apart. The overall response rate at entry to the study was 69%. We exceeded our expected recruitment rate, achieving a total of 10,048 people in all. Reliability coefficients were generally good to excellent. Discussion Response rate to follow-up in all countries was uniformly high, which suggests that prediction will be based on almost a full cohort. The results of our reliability analysis are encouraging and suggest that data collected during the course of PREDICT will have a satisfactory level of stability. The development of a multi-factor risk score for depression will lay the foundation for future research on risk reduction

  4. The InfraRed Imaging Spectrograph (IRIS) for TMT: latest science cases and simulations

    CERN Document Server

    Wright, Shelley A; Do, Tuan; Marshall, Daniel; Larkin, James E; Moore, Anna M; Adamkovics, Mate; Andersen, David; Armus, Lee; Barth, Aaron; Cote, Patrick; Cooke, Jeff; Chisholm, Eric M; Davidge, Timothy; Dunn, Jennifer S; Dumas, Christophe; Ellerbroeck, Brent L; Ghez, Andrea M; Hao, Lei; Hayano, Yutaka; Liu, Michael; Lopez-Rodriguez, Enrique; Lu, Jessica R; Mao, Shude; Marois, Christian; Pandey, Shashi B; Philips, Andrew C; Schoeck, Matthias; Subramaniam, Annapurni; Subramanian, Smitha; Suzuki, Ryuji; Tan, Jonathan C; Terai, Tsuyoshi; Treu, Tommaso; Simard, Luc; Weiss, Jason L; Wincensten, James; Wong, Michael; Zhang, Kai

    2016-01-01

    The Thirty Meter Telescope (TMT) first light instrument IRIS (Infrared Imaging Spectrograph) will complete its preliminary design phase in 2016. The IRIS instrument design includes a near-infrared (0.85 - 2.4 micron) integral field spectrograph (IFS) and imager that are able to conduct simultaneous diffraction-limited observations behind the advanced adaptive optics system NFIRAOS. The IRIS science cases have continued to be developed and new science studies have been investigated to aid in technical performance and design requirements. In this development phase, the IRIS science team has paid particular attention to the selection of filters, gratings, sensitivities of the entire system, and science cases that will benefit from the parallel mode of the IFS and imaging camera. We present new science cases for IRIS using the latest end-to-end data simulator on the following topics: Solar System bodies, the Galactic center, active galactic nuclei (AGN), and distant gravitationally-lensed galaxies. We then briefl...

  5. Malaria Vaccine Adjuvants: Latest Update and Challenges in Preclinical and Clinical Research

    Directory of Open Access Journals (Sweden)

    Elena Mata

    2013-01-01

    Full Text Available There is no malaria vaccine currently available, and the most advanced candidate has recently reported a modest 30% efficacy against clinical malaria. Although many efforts have been dedicated to achieve this goal, the research was mainly directed to identify antigenic targets. Nevertheless, the latest progresses on understanding how immune system works and the data recovered from vaccination studies have conferred to the vaccine formulation its deserved relevance. Additionally to the antigen nature, the manner in which it is presented (delivery adjuvants as well as the immunostimulatory effect of the formulation components (immunostimulants modulates the immune response elicited. Protective immunity against malaria requires the induction of humoral, antibody-dependent cellular inhibition (ADCI and effector and memory cell responses. This review summarizes the status of adjuvants that have been or are being employed in the malaria vaccine development, focusing on the pharmaceutical and immunological aspects, as well as on their immunization outcomings at clinical and preclinical stages.

  6. Hybrid Textures of Neutrino Mass Matrix under the Lamppost of Latest Neutrino and Cosmology Data

    CERN Document Server

    Kalita, Rupam

    2015-01-01

    We study all possible neutrino mass matrices with one zero element and two equal non-zero elements, known as hybrid texture neutrino mass matrices. In the diagonal charged lepton basis, we consider thirty nine such possible cases which are consistent with the latest neutrino data. Using the two constraints on neutrino mass matrix elements imposed by hybrid textures, we numerically evaluate the neutrino parameters like the lightest neutrino mass $m_{\\text{lightest}}$, one Dirac CP phase $\\delta$ and two Majorana CP phases $\\alpha, \\beta$ by using the global fit $3\\sigma$ values of three mixing angles and two mass squared differences. We then constrain this parameter space by using the cosmological upper bound on the sum of absolute neutrino masses given by Planck experiment. We also calculate the effective neutrino mass matrix for this region of parameter space which may have relevance in future neutrinoless double beta decay experiments. We finally discriminate between these hybrid texture mass matrices from ...

  7. A General Framework for Sequential and Adaptive Methods in Survival Studies

    CERN Document Server

    Luo, Xiaolong; Ying, Zhiliang

    2011-01-01

    Adaptive treatment allocation schemes based on interim responses have generated a great deal of recent interest in clinical trials and other follow-up studies. An important application of such schemes is in survival studies, where the response variable of interest is time to the occurrence of a certain event. Due to possible dependency structures inherited from the enrollment and allocation schemes, existing approaches to survival models, including those that handle staggered entry, cannot be applied directly. This paper develops a new general framework with its theoretical foundation for handling such adaptive designs. The new approach is based on marked point processes and differs from existing approaches in that it considers entry and calender times rather than survival and calender times. Large sample properties, which are essential for statistical inference, are established. Special attention is given to the Cox model and related score processes. Applications to adaptive and sequential designs are discus...

  8. Self-study program on HTML browser--application to Clinical Nursing General Remarks Course.

    Science.gov (United States)

    Ochiai, N; Sota, Y; Ezumi, H

    1997-01-01

    We created a self-study program using HTML browser on the Clinical Nursing General Remarks Course, Eighty-three students each selected a published book on a personal history (written personal reflections from individuals who had undergone medical treatment and hospitalization), read it and submitted reports of their impressions of the histories. Their reports were arranged from a nursing perspective and entered on the home page of our college using HTML browser. We intended that the students would become more interested in reading of the personal histories, and that they would acquire new self-study skills and increase their interest in Internet through use of our program. In addition, we hoped that this program would encourage positive communication and mutual sharing of information. The students were able to easily refer to a personal history according to their interest from a nursing perspective. Therefore this program realized the mutual learning among students and other users.

  9. A reliability generalization study of coefficient alpha for the UCLA loneliness scale.

    Science.gov (United States)

    Vassar, Matt; Crosby, James W

    2008-11-01

    Loneliness is a psychological construct that has been reported in a variety of populations and associated with a number of other negative psychological problems. This study was an examination of coefficient alpha of a prominent measure of loneliness: the University of California, Los Angeles (UCLA) Loneliness Scale (Russell, Peplau, & Cutrona, 1980; Russell, 1996). We utilized reliability generalization to provide an aggregate estimate of the reliability of the scale over time and in a variety of populations as well as to assess and identify sampling and demographic characteristics associated with variability in coefficient alpha. Of the 213 studies examined, 80 had reported alpha estimates, and we used them in this analysis. We discuss conditions associated with variability in coefficient alpha along with pertinent implications for practice and future research.

  10. Identification and diagnostic evaluation of possible dementia in general practice. A prospective study

    DEFF Research Database (Denmark)

    Waldorff, Frans Boch; Rishøj, Susanne; Waldemar, Gunhild

    2005-01-01

    OBJECTIVE: To investigate the rate of diagnostic evaluation of dementia for patients in whom a suspicion of dementia was raised, and to investigate reasons why a diagnostic evaluation was not always being performed. DESIGN: A prospective study among elderly patients aged 65+, and a follow-up study......, and 4 (3%) were treated for depression or referred for another condition. A total of 6 patients were lost to follow-up. In the remaining 102 undiagnosed patients the main reasons for not performing a diagnostic evaluation of dementia were patient/relative hesitation (34%), the GP thought that it would...... not have any consequences for the patient, or the GP estimated that the patient was too fragile (21%). CONCLUSION: In 17% of elderly patients in general practice a suspicion of dementia could be raised based on the clinical impression of the GP or MMSE score. However, only 23% of this group were evaluated...

  11. Systematic review of general burden of disease studies using disability-adjusted life years

    Directory of Open Access Journals (Sweden)

    Polinder Suzanne

    2012-11-01

    Full Text Available Abstract Objective To systematically review the methodology of general burden of disease studies. Three key questions were addressed: 1 what was the quality of the data, 2 which methodological choices were made to calculate disability adjusted life years (DALYs, and 3 were uncertainty and risk factor analyses performed? Furthermore, DALY outcomes of the included studies were compared. Methods Burden of disease studies (1990 to 2011 in international peer-reviewed journals and in grey literature were identified with main inclusion criteria being multiple-cause studies that quantified the burden of disease as the sum of the burden of all distinct diseases expressed in DALYs. Electronic database searches included Medline (PubMed, EMBASE, and Web of Science. Studies were collated by study population, design, methods used to measure mortality and morbidity, risk factor analyses, and evaluation of results. Results Thirty-one studies met the inclusion criteria of our review. Overall, studies followed the Global Burden of Disease (GBD approach. However, considerable variation existed in disability weights, discounting, age-weighting, and adjustments for uncertainty. Few studies reported whether mortality data were corrected for missing data or underreporting. Comparison with the GBD DALY outcomes by country revealed that for some studies DALY estimates were of similar magnitude; others reported DALY estimates that were two times higher or lower. Conclusions Overcoming “error” variation due to the use of different methodologies and low-quality data is a critical priority for advancing burden of disease studies. This can enlarge the detection of true variation in DALY outcomes between populations or over time.

  12. Feasibility and acceptance of electronic quality of life assessment in general practice: an implementation study

    Directory of Open Access Journals (Sweden)

    Kochen Michael M

    2009-06-01

    Full Text Available Abstract Background Patients' health related quality of life (HRQoL has rarely been systematically monitored in general practice. Electronic tools and practice training might facilitate the routine application of HRQoL questionnaires. Thorough piloting of innovative procedures is strongly recommended before the conduction of large-scale studies. Therefore, we aimed to assess i the feasibility and acceptance of HRQoL assessment using tablet computers in general practice, ii the perceived practical utility of HRQoL results and iii to identify possible barriers hindering wider application of this approach. Methods Two HRQoL questionnaires (St. George's Respiratory Questionnaire SGRQ and EORTC QLQ-C30 were electronically presented on portable tablet computers. Wireless network (WLAN integration into practice computer systems of 14 German general practices with varying infrastructure allowed automatic data exchange and the generation of a printout or a PDF file. General practitioners (GPs and practice assistants were trained in a 1-hour course, after which they could invite patients with chronic diseases to fill in the electronic questionnaire during their waiting time. We surveyed patients, practice assistants and GPs regarding their acceptance of this tool in semi-structured telephone interviews. The number of assessments, HRQoL results and interview responses were analysed using quantitative and qualitative methods. Results Over the course of 1 year, 523 patients filled in the electronic questionnaires (1–5 times; 664 total assessments. On average, results showed specific HRQoL impairments, e.g. with respect to fatigue, pain and sleep disturbances. The number of electronic assessments varied substantially between practices. A total of 280 patients, 27 practice assistants and 17 GPs participated in the telephone interviews. Almost all GPs (16/17 = 94%; 95% CI = 73–99%, most practice assistants (19/27 = 70%; 95% CI = 50–86% and the majority of

  13. Atopic children and use of prescribed medication: A comprehensive study in general practice.

    Science.gov (United States)

    Pols, David H J; Nielen, Mark M J; Bohnen, Arthur M; Korevaar, Joke C; Bindels, Patrick J E

    2017-01-01

    A comprehensive and representative nationwide general practice database was explored to study associations between atopic disorders and prescribed medication in children. All children aged 0-18 years listed in the NIVEL Primary Care Database in 2014 were selected. Atopic children with atopic eczema, asthma and allergic rhinitis (AR) were matched with controls (not diagnosed with any of these disorders) within the same general practice on age and gender. Logistic regression analyses were performed to study the differences in prescribed medication between both groups by calculating odds ratios (OR); 93 different medication groups were studied. A total of 45,964 children with at least one atopic disorder were identified and matched with controls. Disorder-specific prescriptions seem to reflect evidence-based medicine guidelines for atopic eczema, asthma and AR. However, these disorder-specific prescriptions were also prescribed for children who were not registered as having that specific disorder. For eczema-related medication, about 3.7-8.4% of the children with non-eczematous atopic morbidity received these prescriptions, compared to 1.4-3.5% of the non-atopic children. The same pattern was observed for anti-asthmatics (having non-asthmatic atopic morbidity: 0.8-6.2% vs. controls: 0.3-2.1%) and AR-related medication (having non-AR atopic morbidity: 4.7-12.5% vs. controls: 2.8-3.1%). Also, non-atopic related medication, such as laxatives and antibiotics were more frequently prescribed for atopic children. The present study shows that atopic children received more prescriptions, compared to non-atopic children. Non-atopic controls frequently received specific prescriptions for atopic disorders. This indicates that children with atopic disorders need better monitoring by their GP.

  14. Relationship between Metabolic Syndrome Components and Periodontal Disease in a Japanese General Population: the Suita Study.

    Science.gov (United States)

    Kikui, Miki; Kokubo, Yoshihiro; Ono, Takahiro; Kida, Momoyo; Kosaka, Takayuki; Yamamoto, Masaaki; Watanabe, Makoto; Maeda, Yoshinobu; Miyamoto, Yoshihiro

    2017-05-01

    A positive association between metabolic syndrome (MetS) and periodontal status has recently been noted. However, no study has evaluated the relationship by sex and in a general urban population using the uniform definition proposed in the 2009 Joint Interim Statement. The aim of this study was to clarify the relationship between MetS and periodontal status using the uniform definition in a general urban Japanese population. A total of 1,856 Japanese men and women (mean age: 66.4 years) were studied using data from the Suita study. Periodontal status was evaluated by the Community Periodontal Index (CPI). MetS was defined using the 2009 Joint Interim Statement. The associations of the MetS and its components with periodontal disease were investigated using multiple logistic regression analysis adjusting for age, drinking, and smoking. Among the components of the MetS, low HDL cholesterol level was significantly associated with periodontal disease in men and women [odds ratios (OR)=2.39 and 1.53; 95% confidence intervals=1.36-4.19 and 1.06-2.19]. Furthermore, the risk of periodontal disease showed 1.43-, 1.42-, and 1.89-fold increases in those with 2, 3, and ≥4 components, respectively, compared with those having no components (Ptrend <0.001). For the analysis by sex, the risk of periodontal disease was increased 2.27- and 1.76-fold in those with ≥4 components in men and women, respectively (both Ptrend=0.001). These findings suggest that MetS and lower HDL cholesterol are associated with periodontal disease. Subjects with two or more MetS components had a significantly higher prevalence of periodontal disease.

  15. Incidence of Awareness with Recall under General Anesthesia in Rural India: An Observational Study

    Science.gov (United States)

    Singla, Deepak; Mangla, Mishu

    2017-01-01

    Context: Awareness under anesthesia is a rare but extremely unpleasant phenomenon. There are very few studies in the developing world and none from rural areas where incidence of intraoperative awareness may be higher due to increased patient load, limited patient knowledge and lack of trained hospital staff, reliance on older, cheaper but less effective drugs, and lack of proper equipment both for providing anesthesia, as well as monitoring the patient. Aims: To assess the incidence of intraoperative awareness during general anesthesia among patients in rural India and any factors associated with the same. Settings and Design: Prospective, nonrandomized, observational study. Subjects and Methods: Patients undergoing elective surgical procedures in various specialties under general anesthesia from over a period of 1 year were considered for this study. Approximately, after 1 h of arrival in postanaesthesia care unit, anesthesiologist (not involved in administering anesthesia) assessed intraoperative awareness using a modified form of Brice questionnaire. Statistical Analysis Used: Data were collected on a Microsoft Excel® sheet and analyzed using Statistical Package for the Social Sciences® version 23 (SPSS Inc., Chicago, IL, USA) for windows. Results: A total of 896 patients completed the questionnaire. Postoperatively, in response to the questionnaire, seven patients reported to have remembered something under anesthesia. Out of these, three patients described events that were confirmed by operation theater staff to have occurred whereas they were under anesthesia. Conclusions: Incidence of definite awareness under anesthesia with postoperative recall was found to be 0.33% (three patients out of total 896) in our study. PMID:28663647

  16. Are general surgery residents adequately prepared for hepatopancreatobiliary fellowships? A questionnaire-based study

    Science.gov (United States)

    Osman, Houssam; Parikh, Janak; Patel, Shirali; Jeyarajah, D Rohan

    2015-01-01

    Background The present study was conducted to assess the preparedness of hepatopancreatobiliary (HPB) fellows upon entering fellowship, identify challenges encountered by HPB fellows during the initial part of their HPB training, and identify potential solutions to these challenges that can be applied during residency training. Methods A questionnaire was distributed to all HPB fellows in accredited HPB fellowship programmes in two consecutive academic years (n = 42). Reponses were then analysed. Results A total of 19 (45%) fellows responded. Prior to their fellowship, 10 (53%) were in surgical residency and the rest were in other surgical fellowships or surgical practice. Thirteen (68%) were graduates of university-based residency programmes. All fellows felt comfortable in performing basic laparoscopic procedures independently at the completion of residency and less comfortable in performing advanced laparoscopy. Eight (42%) fellows cited a combination of inadequate case volume and lack of autonomy during residency as the reasons for this lack of comfort. Thirteen (68%) identified inadequate preoperative workup and management as their biggest fear upon entering practice after general surgery training. A total of 17 (89%) fellows felt they were adequately prepared to enter HPB fellowship. Extra rotations in transplant, vascular or minimally invasive surgery were believed to be most helpful in preparing general surgery residents pursing HPB fellowships. Conclusions Overall, HPB fellows felt themselves to be adequately prepared for fellowship. Advanced laparoscopic procedures and the perioperative management of complex patients are two of the challenges facing HPB fellows. General surgery residents who plan to pursue an HPB fellowship may benefit from spending extra rotations on certain subspecialties. Focus on perioperative workup and management should be an integral part of residency and fellowship training. PMID:25387852

  17. A paradigm for the study of paranoia in the general population: the Prisoner's Dilemma Game.

    Science.gov (United States)

    Ellett, Lyn; Allen-Crooks, Rhani; Stevens, Adele; Wildschut, Tim; Chadwick, Paul

    2013-01-01

    A growing body of research shows that paranoia is common in the general population. We report three studies that examined the Prisoner's Dilemma Game (PDG) as a paradigm for evaluation of non-clinical paranoia. The PDG captures three key qualities that are at the heart of paranoia--it is interpersonal, it concerns threat, and it concerns the perception of others' intentions towards the self. Study 1 (n=175) found that state paranoia was positively associated with selection of the competitive PDG choice. Study 2 (n=111) found that this association was significant only when participants believed they were playing the PDG against another person, and not when playing against a computer. This finding underscores the interpersonal nature of paranoia and the concomitant necessity of studying paranoia in interpersonal context. In Study 3 (n=152), we assessed both trait and state paranoia, and differentiated between distrust- and greed-based competition. Both trait and state paranoia were positively associated with distrust-based competition (but not with greed-based competition). Crucially, we found that the association between trait paranoia and distrust-based competition was fully mediated by state paranoia. The PDG is a promising paradigm for the study of non-clinical paranoia.

  18. [Review of studies on generalized self-efficacy and the explanatory potential of epigenetic theory].

    Science.gov (United States)

    Miyoshi, Akiko; Ono, Hisashi

    2011-02-01

    In this article, we review studies of generalized self-efficacy (GSE) involving the characteristics, measurement, changes, and formation of GSE. We discuss controversial issues regarding developmental changes in GSE, such as the age at which GSE develops and becomes established, and its causal direction, i.e., does task-specific self-efficacy have an effect on GSE, or does GSE have an effect on task-specific self-efficacy. We suggest that studies of GSE should be designed to address these questions. Since it is possible to study the long-term development of GSE using epigenetic theory, we suggest that this theory should be the theoretical framework for GSE studies. GSE studies would also benefit from consideration of the theory of competence (concept of virtue) based on the perspective of healthy ego-development. Moreover, not only positive aspects of GSE, but also negative aspects, such as over-aspiration, should be investigated. We conclude that multifaceted studies of GSE based on theories of personality development should be undertaken.

  19. Genome-wide association study of autistic-like traits in a general population study of young adults

    Directory of Open Access Journals (Sweden)

    Rachel Maree Jones

    2013-10-01

    Full Text Available Research has proposed that autistic-like traits in the general population lie on a continuum, with clinical Autism Spectrum Disorder (ASD representing the extreme end of this distribution. Inherent in this proposal is that biological mechanisms associated with clinical ASD may also underpin variation in autistic-like traits within the general population. A genome-wide association study using 2,462,046 single nucleotide polymorphisms (SNPs was undertaken for ASD in 965 individuals from the Western Australian Pregnancy Cohort (Raine Study. No SNP associations reached genome-wide significance (p < 5.0 x 10-8. However, investigations into nominal observed SNP associations (p < 1.0 x 10-5 add support to two positional candidate genes previously implicated in ASD aetiology, PRKCB1 and CBLN1.The rs198198 SNP (p = 9.587 x 10-6, is located within an intron of the protein kinase C, beta 1 (PRKCB1 gene on chromosome 16p11. The PRKCB1 gene has been previously reported in linkage and association studies for ASD, and its mRNA expression has been shown to be significantly down regulated in ASD cases compared with controls. The rs16946931 SNP (p = 1.78 x 10-6 is located in a region flanking the Cerebellin 1 (CBLN1 gene on chromosome 16q12.1. The CBLN1 gene is involved with synaptogenesis and is part of a gene family previously implicated in ASD. This GWA study is only the second to examine SNPs associated with autistic-like traits in the general population, and provides evidence to support roles for the PRKCB1 and CBLN1 genes in risk of clinical ASD.

  20. A Study of the Relationship between Observed and Reported Use of a Cappella Singing in the Elementary General Music Classroom

    Science.gov (United States)

    Baker, Valerie Anne

    2010-01-01

    The purpose of this study was to investigate any relationship between observed and reported use of a cappella singing in the elementary general music classroom. A secondary purpose of this study was to examine teachers' practical perspectives influencing the use of a cappella singing in the elementary general music classroom. From a total of 50…

  1. Latest Pleistocene to Holocene hydroclimates from Lake Elsinore, California

    Science.gov (United States)

    Kirby, Matthew E.; Feakins, Sarah J.; Bonuso, Nicole; Fantozzi, Joanna M.; Hiner, Christine A.

    2013-09-01

    The hydroclimate of the southwestern United States (US) region changed abruptly during the latest Pleistocene as the continental ice sheets over North America retreated from their most southerly extent. To investigate the nature of this change, we present a new record from Lake Elsinore, located 36 km inland from the Pacific Ocean in Southern California and evaluate it in the context of records across the coastal and interior southwest United States, including northwest Mexico. The sediment core recovered from Lake Elsinore provides a continuous sequence with multi-decadal resolution spanning 19-9 ka BP. Sedimentological and geochemical analyses reveal hydrologic variability. In particular, sand and carbonate components indicate abrupt changes at the Oldest Dryas (OD), Bølling-Allerød (BA), and Younger Dryas (YD) transitions, consistent with the timing in Greenland. Hydrogen isotope analyses of the C28n-alkanoic acids from plant leaf waxes (δDwax) reveal a long term trend toward less negative values across 19-9 ka BP. δDwax values during the OD suggest a North Pacific moisture source for precipitation, consistent with the dipping westerlies hypothesis. We find no isotopic evidence for the North American Monsoon reaching as far west as Lake Elsinore; therefore, we infer that wet/dry changes in the coastal southwest were expressed through winter-season precipitation, consistent with modern climatology. Comparing Lake Elsinore to other southwest records (notably Cave of Bells and Fort Stanton) we find coincident timing of the major transitions (OD to BA, BA to YD) and hydrologic responses during the OD and BA. The hydrologic response, however, varied during the YD consistent with a dipole between the coastal and interior southwest. The coherent pattern of hydrologic responses across the interior southwest US and northwest Mexico during the OD (wet), the BA (drier), and YD (wet) follows changes in the Atlantic Meridional Overturning Circulation, presumably via its

  2. Global Energy and Water Balances in the Latest Reanalyses

    Science.gov (United States)

    Ahn, Joong-Bae; Kang, Suchul; Park, Hye-Jin

    2016-04-01

    Administration Research and Development Program under grant KMIPA2015-2081. References Suchul Kang and Joong-Bae Ahn (2015) Global Energy and Water Balances in the Latest Reanalyses, Asia-Pac. J. Atmos. Sci. 51(4), 293-302.

  3. Challenges in the care for consanguineous couples: an exploratory interview study among general practitioners and midwives

    Directory of Open Access Journals (Sweden)

    Teeuw Marieke E

    2012-10-01

    Full Text Available Abstract Background It is often suggested that an effort must be made to increase awareness among consanguineous couples of their reproductive risk, and to refer them for genetic counseling if needed. Primary care professionals are considered most appropriate for addressing the subject and identifying couples at risk during consultations in their practice. This Dutch study aims to explore the experiences, attitudes and beliefs of such professionals regarding their care for consanguineous couples. Methods Sixteen semi-structured interviews were conducted with midwives and general practitioners. Results Although most primary care professionals considered it their task to inform couples about the risks of consanguinity, during consultations the topic was generally only briefly touched upon and quickly abandoned. Important reasons for this were professionals’ beliefs about religious and social values of couples, their low perception of the couples’ reproductive risk and expected limited feasibility of referral. Feelings of embarrassment regarding addressing consanguinity did not seem to play a significant role. Conclusions Primary care professional beliefs about their clients’ religious and social values, their attitudes toward the risk, and perceived limited options for referral seem to conflict with the professional norm to address the topic of consanguinity.

  4. Arousal Predisposition as a Vulnerability Indicator for Psychosis: A General Population Online Stress Induction Study

    Directory of Open Access Journals (Sweden)

    Annika Clamor

    2015-01-01

    Full Text Available Explanatory models ascribe to arousability a central role for the development of psychotic symptoms. Thus, a disposition to hyperarousal (i.e., increased arousal predisposition (AP may serve as an underlying vulnerability indicator for psychosis by interacting with stressors to cause symptoms. In this case, AP, stress-response, and psychotic symptoms should be linked before the development of a diagnosable psychotic disorder. We conducted a cross-sectional online study in a population sample (N=104; Mage=27.7 years, SD=11.2, range 18–70. Participants rated their AP and subclinical psychotic symptoms. Participants reported their stress-levels before and after two stress inductions including an arithmetic and a social stressor. The participants with an increased AP generally felt more stressed. However, AP was not associated with the specific stress-response. As expected, positive psychotic symptoms were significantly associated with AP, but this was not mediated by general stress-levels. Its association to subtle, nonclinical psychotic symptoms supports our assumption that AP could be a vulnerability indicator for psychosis. The trait is easily accessible via a short self-report and could facilitate the identification of people at risk and be a promising target for early stress-management. Further research is needed to clarify its predictive value for stress-responses.

  5. How can a postgraduate professional education and development course benefit general practitioners?: a qualitative study

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    Steven Agius

    2015-06-01

    Full Text Available Purpose: The rationale for ‘professional education and development’ (PED courses is to support general practitioners, enabling them to access a range of theoretical and practical skills within a supportive schema. It aims to identify whether and how a regional PED course has had a beneficial impact upon participants. Methods: The study comprised a qualitative investigation of participants’ assessed coursework portfolios. The content of each portfolio gives individual accounts of the impact of the course on personal and practice development. Permission to access extant portfolios was obtained from 16 recent alumni of the course. The anonymous written material was analysed by the research team for recurring discourses and themes using a thematic framework analysis. Results: Seven major thematic categories were extrapolated from the data: leadership, resilience, quality improvement, change management, development of new services, educational expertise, and patient safety. In each category, we found evidence that the course enabled development of practitioners by enhancing knowledge and skills which had a positive impact upon their self-perceived effectiveness and motivation. Conclusion: Extended specialty training is on the horizon but such courses may still serve a valuable purpose for current trainees and the existing general practitioners workforce which will be responsible for leading the shift towards community-based service delivery.

  6. A study on concept of P- drug selection among rural general practitioners

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    Priyadarshini Bai G.

    2016-12-01

    Full Text Available Background: The objective of the study was to assess the awareness of P- drug selection among rural general practitioners’s (GP for common medical conditions. Methods: Fifty general practitioners in Tumakuru district were provided with proformas for selection of P- drugs for mild to moderate hypertension, diabetes, upper respiratory tract infections and acid peptic disease based on safety, affordability, need, and efficacy (SANE criteria. Results: Forty one GP’s responded by completing the proformas. Seventeen of them were aware of the concept of P- drug selection. In hypertension, beta blockers followed by Angiotensin Converting Enzyme (ACE inhibitors were most commonly preferred. In diabetes, biguanides followed by sulfonylureas were preferred as oral hypoglycemic agents. Ampicillin, Ciprofloxacin and Cotrimoxazole were the commonly used antibiotics for upper respiratory tract infections. Ranitidine and antacids were preferred for acid peptic disease. Affordability followed by efficacy was the deciding criteria for P- drug selection. Conclusions: There is lack of awareness of P- drug selection among many rural GP’s. Therefore, there is necessity to create awareness about P- drug selection through continued medical education for rational use of drugs.

  7. EXPERIMENTAL STUDY ON INCIPIENT MOTION OF SEDIMENT PARTICLES ON GENERALIZED SLOPING FLUVIAL BEDS

    Institute of Scientific and Technical Information of China (English)

    Subhasish DEY

    2001-01-01

    This paper presents an experimental investigation on incipient motion of non-cohesive uniform sediment under a steady-uniform stream flow on generalized sloping fluvial beds (combined lateral and stream-wise slope). The characteristic parameters affecting the incipient motion of sediment particles, identified based on the physical reasoning and dimensional analysis, are the threshold shear stress ratio (ratio of threshold shear stress for sloping bed to that for horizontal bed), lateral slope,stream-wise slope and angle of repose of sediment particles. Experiments were carried out in two ducts (closed-conduit flow) having section of semicircular invert with three types of sediments. In an open channel flow (laboratory flume study), the uniform flow is a difficult, if not impossible,proposition for a steeply sloping channel and is impossible to obtain in an adversely sloping channel.To avoid this problem, the tests were conducted with a closed-conduit flow. Equation of critical bed shear stress for the initial movement of sediment particles on generalized sloping beds was obtained using the experimental data.

  8. Genome-wide association study of autistic-like traits in a general population study of young adults.

    Science.gov (United States)

    Jones, Rachel Maree; Cadby, Gemma; Melton, Phillip E; Abraham, Lawrence J; Whitehouse, Andrew J; Moses, Eric K

    2013-01-01

    Lay abstract: It has been proposed that autistic-like traits in the general population lie on a continuum, with clinical Autism Spectrum Disorder (ASD), representing the extreme end of this distribution. The current study undertook a genome-wide association (GWA) scan of 965 young Western Australian adults to identify novel risk variants associated with autistic-like traits. No associations reached genome-wide significance; however, a review of nominally associated single nucleotide polymorphisms (SNPs) indicated two positional candidate loci that have been previously implicated in autistic-like trait etiology. Scientific abstract: Research has proposed that autistic-like traits in the general population lie on a continuum, with clinical ASD representing the extreme end of this distribution. Inherent in this proposal is that biological mechanisms associated with clinical ASD may also underpin variation in autistic-like traits within the general population. A GWA study using 2,462,046 SNPs was undertaken for ASD in 965 individuals from the Western Australian Pregnancy Cohort (Raine) Study. No SNP associations reached genome-wide significance (p CBLN1. The rs198198 SNP (p = 9.587 × 10(-6)), is located within an intron of the protein kinase C, beta 1 (PRKCB1) gene on chromosome 16p11. The PRKCB1 gene has been previously reported in linkage and association studies for ASD, and its mRNA expression has been shown to be significantly down regulated in ASD cases compared with controls. The rs16946931 SNP (p = 1.78 × 10(-6)) is located in a region flanking the Cerebellin 1 (CBLN1) gene on chromosome 16q12.1. The CBLN1 gene is involved with synaptogenesis and is part of a gene family previously implicated in ASD. This GWA study is only the second to examine SNPs associated with autistic-like traits in the general population, and provides evidence to support roles for the PRKCB1 and CBLN1 genes in risk of clinical ASD.

  9. STUDY ON THE USE PATTERN OF NSAIDS IN SOME GENERAL AND SPECIALIZED HOSPITALS OF BANGLADESH

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    Hasan Md. Mahadi

    2012-02-01

    Full Text Available This study was designed to assess the present use pattern of both traditional nonsteroidal anti-inflammatory drugs (tNSAIDs and cyclooxygenase 2 (COX-2-selective NSAIDs (coxibs in terms of demographic characteristics, prevalence of use of NSAIDs type, gastro-protective drug use frequency among the patients of four general hospitals and another five specialized hospitals of Dhaka city. The study was conducted during 3 May to 18 May 2011. Total 480 patients were asked to answer the questions of the previously designed questionnaire covered with some closed ended dichotomous and multichotomous questions. Most prevalent age group of the patients was between 40-65years. Again, use of tNSAIDs was relatively higher than that of coxibs. Besides, among the NSAIDs, ketorolac tromethamine (a tNSAID was the most frequently used drug (29.3% in the general hospitals (GnH whereas diclofenac sodium (a tNSAID was common (58% in the specialized hospitals (SpH counterpart. Moreover, a significant number of patients did not use gastro-protective medication whenever taking NSAIDs. Most prevailing gastroprotectives were Proton Pump Inhibitor (PPI and H2 receptor antagonist. Apart from these, another critical observation from this study was the lack of following proper indication related to medication specially for taking the gastroprotective drugs. In conclusion, it can be said that although in most cases, the use pattern of NSAIDs is proper and justified but to avoid unwanted complications and misuse of the drugs, both physicians as well as drug users need to be more aware.

  10. Study of Patients Absconding Behavior in a General Hospital at Southern Region of Iran

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    Mohammad Khammarnia

    2015-03-01

    Full Text Available Background Patients’ escape from hospital imposes a significant cost to patients as well as the health system. Besides, for these patients, exposure to adverse events (such as suicide, self-harm, violence and harm to hospital reputation are more likely to occur compared to others. The present study aimed to determine the characteristics of the absconding patients in a general hospital through a case-control design in Shiraz, Iran. Methods This case-control study was conducted on 413 absconded patients as case and 413 patients as control in a large general hospital in Shiraz, southern Iran. In this study, data on the case and control patients was collected from the medical records using a standard checklist in the period of 2011–3. Then, the data were analyzed using descriptive and analytical statistics, through SPSS 16. Results The finding showed that 413 patients absconded (0.50% and mean of age in case group was 40.98 ± 16.31 years. In univariate analysis, variables of gender [Odds Ratio (OR= 2], ward (OR= 1.22, insurance status (OR= 0.41, job status (OR= 0.34 and residence expenditure were significant. However, in multivariate analysis significant variables were age (ORadj= 0.13, gender (ORadj= 2.15, self-employment/unemployed (ORadj= 0.47, emergency/admission (ORadj= 2.14, internal/admission (ORadj= 3.16, insurance status (ORadj= 4.49 and residence expenditure (ORadj= 1.15. Conclusion Characteristics such as middle age, male gender, no insurance coverage, inability to afford hospital expenditures and admission in emergency department make patients more likely abscond from the hospital. Therefore, it may be necessary to focus efforts on high-risk groups and increase insurance coverage in the country to prevent absconding from hospital.

  11. A Qualitative Study of Prescription Contraception Use: The Perspectives of Users, General Practitioners and Pharmacists.

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    Leigh-Ann Sweeney

    Full Text Available The oral contraceptive pill (OCP remains the most popular form of prescription contraception in many countries, despite adherence difficulties for many. Uptake of long acting reversible contraceptives (LARCs, which are less reliant on user adherence, remains low. The aim of this study was to explore the experiences of, and attitudes towards, prescription contraception amongst samples of contraception users, general practitioners (GPs and pharmacists.We conducted a qualitative study using semi-structured interviews with 18 contraception users, 18 GPs and 9 pharmacists. The study took place in Galway, Republic of Ireland between June and September 2014. Thematic analysis was used to analyse the data. Overall, contraception users were more familiar with the OCP, and all the women interviewed began their prescription contraception journey using this method. All participants identified episodes of poor adherence throughout the reproductive life course. The identified barriers for use of LARCs were lack of information, misconceptions, lack of access and high cost. In contrast, GPs believed that adherence to the OCP was good and stated they were more likely to prescribe the OCP than other methods, as they were most familiar with this option. Barriers to prescribing LARCSs were time, cost to practice, training and deskilling. Pharmacists also believed that adherence to the OCP was generally good and that their role was limited to dispensing medication and providing information when asked.There are contrasting perspectives between contraception service providers and contraceptive users. Training for healthcare providers is required to support informed contraceptive choice and adherence. It is necessary to address the practice barriers of cost and lack of time, to promote better communication around adherence issues and prescription contraception options. There is a need for more easily-accessible public health information to promote awareness on all

  12. MRSA model of learning and adaptation: a qualitative study among the general public

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    Rohde Rodney E

    2012-04-01

    Full Text Available Abstract Background More people in the US now die from Methicillin Resistant Staphylococcus aureus (MRSA infections than from HIV/AIDS. Often acquired in healthcare facilities or during healthcare procedures, the extremely high incidence of MRSA infections and the dangerously low levels of literacy regarding antibiotic resistance in the general public are on a collision course. Traditional medical approaches to infection control and the conventional attitude healthcare practitioners adopt toward public education are no longer adequate to avoid this collision. This study helps us understand how people acquire and process new information and then adapt behaviours based on learning. Methods Using constructivist theory, semi-structured face-to-face and phone interviews were conducted to gather pertinent data. This allowed participants to tell their stories so their experiences could deepen our understanding of this crucial health issue. Interview transcripts were analysed using grounded theory and sensitizing concepts. Results Our findings were classified into two main categories, each of which in turn included three subthemes. First, in the category of Learning, we identified how individuals used their Experiences with MRSA, to answer the questions: What was learned? and, How did learning occur? The second category, Adaptation gave us insights into Self-reliance, Reliance on others, and Reflections on the MRSA journey. Conclusions This study underscores the critical importance of educational programs for patients, and improved continuing education for healthcare providers. Five specific results of this study can reduce the vacuum that currently exists between the knowledge and information available to healthcare professionals, and how that information is conveyed to the public. These points include: 1 a common model of MRSA learning and adaptation; 2 the self-directed nature of adult learning; 3 the focus on general MRSA information, care and

  13. General and specialized brain correlates for analogical reasoning: A meta-analysis of functional imaging studies.

    Science.gov (United States)

    Hobeika, Lucie; Diard-Detoeuf, Capucine; Garcin, Béatrice; Levy, Richard; Volle, Emmanuelle

    2016-05-01

    Reasoning by analogy allows us to link distinct domains of knowledge and to transfer solutions from one domain to another. Analogical reasoning has been studied using various tasks that have generally required the consideration of the relationships between objects and their integration to infer an analogy schema. However, these tasks varied in terms of the level and the nature of the relationships to consider (e.g., semantic, visuospatial). The aim of this study was to identify the cerebral network involved in analogical reasoning and its specialization based on the domains of information and task specificity. We conducted a coordinate-based meta-analysis of 27 experiments that used analogical reasoning tasks. The left rostrolateral prefrontal cortex was one of the regions most consistently activated across the studies. A comparison between semantic and visuospatial analogy tasks showed both domain-oriented regions in the inferior and middle frontal gyri and a domain-general region, the left rostrolateral prefrontal cortex, which was specialized for analogy tasks. A comparison of visuospatial analogy to matrix problem tasks revealed that these two relational reasoning tasks engage, at least in part, distinct right and left cerebral networks, particularly separate areas within the left rostrolateral prefrontal cortex. These findings highlight several cognitive and cerebral differences between relational reasoning tasks that can allow us to make predictions about the respective roles of distinct brain regions or networks. These results also provide new, testable anatomical hypotheses about reasoning disorders that are induced by brain damage. Hum Brain Mapp 37:1953-1969, 2016. © 2016 Wiley Periodicals, Inc.

  14. Vitamin D status and incident cardiovascular disease and all-cause mortality: a general population study.

    Science.gov (United States)

    Skaaby, Tea; Husemoen, Lise Lotte Nystrup; Pisinger, Charlotta; Jørgensen, Torben; Thuesen, Betina Heinsbæk; Fenger, Mogens; Linneberg, Allan

    2013-06-01

    Low vitamin D status has been associated with cardiovascular disease (CVD) and mortality primarily in selected groups, smaller studies, or with self-reported vitamin D intake. We investigated the association of serum vitamin D status with the incidence of a registry-based diagnosis of ischemic heart disease (IHD), stroke, and all-cause mortality in a large sample of the general population. A total of 9,146 individuals from the two population-based studies, Monica10 and Inter99, were included. Measurements of serum 25-hydroxyvitamin D at baseline were carried out using the IDS ISYS immunoassay system in Monica10 and High-performance liquid chromatography in Inter99. Information on CVDs and causes of death was obtained from Danish registries until 31 December 2008. There were 478 cases of IHD, 316 cases of stroke, and 633 deaths during follow-up (mean follow-up 10 years). Cox regression analyses with age as underlying time axis showed a significant association between vitamin D status and all-cause mortality with a HR = 0.95 (P = 0.005) per 10 nmol/l higher vitamin D level. We found no association between vitamin D status and incidence of IHD or stroke (HR = 1.01, P = 0.442 and HR = 1.00, P = 0.920, respectively). In this large general population study, the observed inverse association between serum vitamin D status and all-cause mortality was not explained by a similar inverse association with IHD or stroke.

  15. Objective Sleep Structure and Cardiovascular Risk Factors in the General Population: The HypnoLaus Study

    Science.gov (United States)

    Haba-Rubio, José; Marques-Vidal, Pedro; Andries, Daniela; Tobback, Nadia; Preisig, Martin; Vollenweider, Peter; Waeber, Gérard; Luca, Gianina; Tafti, Mehdi; Heinzer, Raphaël

    2015-01-01

    Study Objectives: To evaluate the association between objective sleep measures and metabolic syndrome (MS), hypertension, diabetes, and obesity. Design: Cross-sectional study. Setting: General population sample. Participants: There were 2,162 patients (51.2% women, mean age 58.4 ± 11.1). Interventions: Patients were evaluated for hypertension, diabetes, overweight/obesity, and MS, and underwent a full polysomnography (PSG). Measurements and Results: PSG measured variables included: total sleep time (TST), percentage and time spent in slow wave sleep (SWS) and in rapid eye movement (REM) sleep, sleep efficiency and arousal index (ArI). In univariate analyses, MS was associated with decreased TST, SWS, REM sleep, and sleep efficiency, and increased ArI. After adjustment for age, sex, smoking, alcohol, physical activity, drugs that affect sleep and depression, the ArI remained significantly higher, but the difference disappeared in patients without significant sleep disordered breathing (SDB). Differences in sleep structure were also found according to the presence or absence of hypertension, diabetes, and overweight/obesity in univariate analysis. However, these differences were attenuated after multivariate adjustment and after excluding subjects with significant SDB. Conclusions: In this population-based sample we found significant associations between sleep structure and metabolic syndrome (MS), hypertension, diabetes, and obesity. However, these associations were cancelled after multivariate adjustment. We conclude that normal variations in sleep contribute little if any to MS and associated disorders. Citation: Haba-Rubio J, Marques-Vidal P, Andries D, Tobback N, Preisig M, Vollenweider P, Waeber G, Luca G, Tafti M, Heinzer R. Objective sleep structure and cardiovascular risk factors in the general population: the HypnoLaus study. SLEEP 2015;38(3):391–400. PMID:25325467

  16. THE GENERAL CONTEXTUAL FRAME FOR PLACING SUPERIOR STUDIES GRADUATES IN THE WORK MARKET

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    FELICIA ANDRIONI

    2013-12-01

    Full Text Available Integration in a workplace is an interaction rapport between the individual and the environment. The process of professional integration is strongly linked to the professional aspiration, individual expectations, motivation, and work satisfaction. Placing young graduates of superior studies on the labour market is a challenge for contemporary society. Identifying a suitable work place as well as the certainty of the attained work place are very important elements for young superior studies graduates in the current context of economic crysis. The difficulties in getting a job for superior studies graduates are most frequently associated with lacks in what regards the speciality practical skills and generally, insertion in the work market is achived by getting a position in fields that are related or even different from the speciality field. In an extremely unstable social and economic context, people’s ability to quickly adapt to the requirements of the labour market is fundamental. In this respect, education and professional training have an important role, contributing to the update of knowledge, skills and qualifications of superior studies graduates or future superior studies graduates, eventually allowing them to stay active, flexible, adapted to the situations and requirements of the labour market.

  17. Receptionist input to quality and safety in repeat prescribing in UK general practice: ethnographic case study.

    Science.gov (United States)

    Swinglehurst, Deborah; Greenhalgh, Trisha; Russell, Jill; Myall, Michelle

    2011-11-03

    To describe, explore, and compare organisational routines for repeat prescribing in general practice to identify contributors and barriers to safety and quality. Ethnographic case study. Four urban UK general practices with diverse organisational characteristics using electronic patient records that supported semi-automation of repeat prescribing. 395 hours of ethnographic observation of staff (25 doctors, 16 nurses, 4 healthcare assistants, 6 managers, and 56 reception or administrative staff), and 28 documents and other artefacts relating to repeat prescribing locally and nationally. Potential threats to patient safety and characteristics of good practice. Observation of how doctors, receptionists, and other administrative staff contributed to, and collaborated on, the repeat prescribing routine. Analysis included mapping prescribing routines, building a rich description of organisational practices, and drawing these together through narrative synthesis. This was informed by a sociological model of how organisational routines shape and are shaped by information and communications technologies. Results Repeat prescribing was a complex, technology-supported social practice requiring collaboration between clinical and administrative staff, with important implications for patient safety. More than half of requests for repeat prescriptions were classed as "exceptions" by receptionists (most commonly because the drug, dose, or timing differed from what was on the electronic repeat list). They managed these exceptions by making situated judgments that enabled them (sometimes but not always) to bridge the gap between the idealised assumptions about tasks, roles, and interactions that were built into the electronic patient record and formal protocols, and the actual repeat prescribing routine as it played out in practice. This work was creative and demanded both explicit and tacit knowledge. Clinicians were often unaware of this input and it did not feature in policy

  18. A cross-cultural study of the structure of comorbidity among common psychopathological syndromes in the general health care setting

    NARCIS (Netherlands)

    Krueger, RF; Chentsova-Dutton, YE; Markon, KE; Goldberg, D; Ormel, J

    2003-01-01

    This study presents analyses of 7 common psychopathological syndromes in the World Health Organization (WHO) Collaborative Study of Psychological Problems in General Health Care (T. B. Ustun & N. Sartorius, 1995). Data on depression, somatization, hypochondriasis, neurasthenia, anxious worry, anxiou

  19. Incident somatic comorbidity after psychosis: Results from a retrospective cohort study based on Flemish general practice data

    NARCIS (Netherlands)

    C. Truyers (Carla); F. Buntinx (Frank); J. de Lepeleire (Jan); M. de Hert (Marc); R. van Winkel (Ruud); B. Aertgeerts (Bert); S. Bartholomeeusen (Stefaan); E.M.E.H. Lesaffre (Emmanuel)

    2011-01-01

    textabstractBackground: Psychotic conditions and especially schizophrenia, have been associated with increased morbidity and mortality. Many studies are performed in specialized settings with a strong focus on schizophrenia. Somatic comorbidity after psychosis is studied, using a general practice co

  20. Latest development in seismic texture analysis for subsurface structure, facies, and reservoir characterization: A review

    Energy Technology Data Exchange (ETDEWEB)

    Gao, Dengliang

    2011-03-01

    In exploration geology and geophysics, seismic texture is still a developing concept that has not been sufficiently known, although quite a number of different algorithms have been published in the literature. This paper provides a review of the seismic texture concepts and methodologies, focusing on latest developments in seismic amplitude texture analysis, with particular reference to the gray level co-occurrence matrix (GLCM) and the texture model regression (TMR) methods. The GLCM method evaluates spatial arrangements of amplitude samples within an analysis window using a matrix (a two-dimensional histogram) of amplitude co-occurrence. The matrix is then transformed into a suite of texture attributes, such as homogeneity, contrast, and randomness, which provide the basis for seismic facies classification. The TMR method uses a texture model as reference to discriminate among seismic features based on a linear, least-squares regression analysis between the model and the data within an analysis window. By implementing customized texture model schemes, the TMR algorithm has the flexibility to characterize subsurface geology for different purposes. A texture model with a constant phase is effective at enhancing the visibility of seismic structural fabrics, a texture model with a variable phase is helpful for visualizing seismic facies, and a texture model with variable amplitude, frequency, and size is instrumental in calibrating seismic to reservoir properties. Preliminary test case studies in the very recent past have indicated that the latest developments in seismic texture analysis have added to the existing amplitude interpretation theories and methodologies. These and future developments in seismic texture theory and methodologies will hopefully lead to a better understanding of the geologic implications of the seismic texture concept and to an improved geologic interpretation of reflection seismic amplitude

  1. A preliminary study for the implementation of general accident management strategies

    Energy Technology Data Exchange (ETDEWEB)

    Yang, Soo Hyung; Kim, Soo Hyung; Jeong, Young Hoon; Chang, Soon Heung [Korea Advanced Institute of Science and Technology, Taejon (Korea, Republic of)

    1997-12-31

    To enhance the safety of nuclear power plants, implementation of accident management has been suggested as one of most important programs. Specially, accident management strategies are suggested as one of key elements considered in development of the accident management program. In this study, generally applicable accident management strategies to domestic nuclear power plants are identified through reviewing several accident management programs for the other countries and considering domestic conditions. Identified strategies are as follows; 1) Injection into the Reactor Coolant System, 2) Depressurize the Reactor Coolant System, 3) Depressurize the Steam Generator, 4) Injection into the Steam Generator, 5) Injection into the Containment, 6) Spray into the Containment, 7) Control Hydrogen in the Containment. In addition, the systems and instrumentation necessary for the implementation of each strategy are also investigated. 11 refs., 3 figs., 3 tabs. (Author)

  2. QSAR study on estrogenic activity of structurally diverse compounds using generalized regression neural network

    Institute of Scientific and Technical Information of China (English)

    JI Li; WANG XiaoDong; LUO Si; QIN Liang; YANG XvShu; LIU ShuShen; WANG LianSheng

    2008-01-01

    Computer-based quantitative structure-activity relationship (QSAR) model has been becoming a powerful tool in understanding the structural requirements for chemicals to bind the estrogen receptor (ER), designing drugs for human estrogen replacement therapy, and identifying potential estrogenic endocrine disruptors, in this study, a simple yet powerful neural network technique, generalized regression neural network (GRNN) was used to develop a QSAR model based on 131 structurally diverse estrogens (training set). Only nine descriptors calculated solely from the molecular structures of compounds selected by objective and subjective feature selections were used as inputs of the GRNN model. The predictive power of the built model was found to be comparable to that of the more traditional techniques but requiring significantly easy implementation and a shorter computation-time. The obtained result indicates that the proposed GRNN model is robust and satisfactory, and can provide a feasible and practical tool for the rapid screening of the estrogenic activity of organic compounds.

  3. A study of constraints on the constitutive relationships of electromagnetic medium based on generally acknowledged truths

    Institute of Scientific and Technical Information of China (English)

    GUO Huiping; LIU Xueguan; YIN Hongcheng; CHAO Zengming; HUANG Peikang

    2005-01-01

    The study of constraints on the constitutive relationships of electromagnetic media is of great importance in the aspects of the medium characteristics analysis, the new article material synthesis and the medium parameters reconstruction, etc. According to the fact that the constitutive relationships should not conflict with the general physical laws, the constraints that the constitutive relationships of electromagnetic medium must satisfy have been summarized in this paper. These constraints include determinacy principle, objectivity principle, causality principle and permission principle. And the parameter constraints of the arbitrary linear homogenous time-invariant medium are obtained following the minimum energy consumption principle. This work provides a new way of ascertaining the constitutive relationships of the electromagnetic medium.

  4. Study on pure IL VIV of a free spanning pipeline under general boundary conditions

    Science.gov (United States)

    Xu, Wan-hai; Xu, Jing-yu; Wu, Ying-xiang; Ji, Chun-ning

    2017-03-01

    Pipeline spans may occur due to natural seabed irregularities or local scour of bed sediment. The pure in-line (IL) vortex-induced vibrations (VIV) analysis of the free spans is an important subject for design of pipeline in uneven seabed. The main objective of this paper is to analyze the characteristics of pure IL VIV of a free spanning pipeline under general boundary conditions. An IL wake oscillator model which can describe the coupling of pipeline structure and fluctuating drag is introduced and employed. The coupled partial differential equations of structure and wake are transformed into a set of ordinary differential equations using two-mode Galerkin method. Some case studies are presented and thoroughly discussed in order to investigate the effects of internal fluid, axial force and boundary conditions on the pure IL VIV.

  5. GPACC program cost work breakdown structure-dictionary. General purpose aft cargo carrier study, volume 3

    Science.gov (United States)

    1985-01-01

    The results of detailed cost estimates and economic analysis performed on the updated Model 101 configuration of the general purpose Aft Cargo Carrier (ACC) are given. The objective of this economic analysis is to provide the National Aeronautics and Space Administration (NASA) with information on the economics of using the ACC on the Space Transportation System (STS). The detailed cost estimates for the ACC are presented by a work breakdown structure (WBS) to ensure that all elements of cost are considered in the economic analysis and related subsystem trades. Costs reported by WBS provide NASA with a basis for comparing competing designs and provide detailed cost information that can be used to forecast phase C/D planning for new projects or programs derived from preliminary conceptual design studies. The scope covers all STS and STS/ACC launch vehicle cost impacts for delivering payloads to a 160 NM low Earth orbit (LEO).

  6. General practitioners learning qualitative research: A case study of postgraduate education.

    Science.gov (United States)

    Hepworth, Julie; Kay, Margaret

    2015-10-01

    Qualitative research is increasingly being recognised as a vital aspect of primary healthcare research. Teaching and learning how to conduct qualitative research is especially important for general practitioners and other clinicians in the professional educational setting. This article examines a case study of postgraduate professional education in qualitative research for clinicians, for the purpose of enabling a robust discussion around teaching and learning in medicine and the health sciences. A series of three workshops was delivered for primary healthcare academics. The workshops were evaluated using a quantitative survey and qualitative free-text responses to enable descriptive analyses. Participants found qualitative philosophy and theory the most difficult areas to engage with, and learning qualitative coding and analysis was considered the easiest to learn. Key elements for successful teaching were identified, including the use of adult learning principles, the value of an experienced facilitator and an awareness of the impact of clinical subcultures on learning.

  7. STUDY OF DROPOUTS FROM A PSYCHIATRIC CLINIC OF A GENERAL HOSPITAL

    Science.gov (United States)

    Gill, H.P.S.; Singh, Gurmeet; Sharma, Kuldip C.

    1990-01-01

    SUMMARY During the study period of three months, out of 425 patients attending the psychiatric clinic of a general hospital, for the first time, 165 (38.8%) did not complete the treatment as prescribed by the doctors and were considered as dropouts. They were contacted at their homes to find out the reasons of the dropping out, were compared with patients, who completed the treatment fully on socio-demographic variables and attitude towards treatment. Dropouts significantly differed from treatment acceptors regarding their income, place of domicile and occupation. Maximum number of patients (59.9%) dropped out after the first visit. Dropouts were the maximum among epileptics, and minimum among the mentally retarded patients. Dropouts were dissatisfied with their experience at the clinic as treatment advised was not of their choice, and they feared bad side effects from ECT and drugs. Long distance of residence from clinic was an important reason for dropping out, besides social and economic reasons. PMID:21927444

  8. Association of General and Abdominal Obesity With Hypertension, Dyslipidemia and Prediabetes in the PREDAPS Study.

    Science.gov (United States)

    Sangrós, F Javier; Torrecilla, Jesús; Giráldez-García, Carolina; Carrillo, Lourdes; Mancera, José; Mur, Teresa; Franch, Josep; Díez, Javier; Goday, Albert; Serrano, Rosario; García-Soidán, F Javier; Cuatrecasas, Gabriel; Igual, Dimas; Moreno, Ana; Millaruelo, J Manuel; Carramiñana, Francisco; Ruiz, Manuel Antonio; Pérez, Francisco Carlos; Iriarte, Yon; Lorenzo, Ángela; González, María; Álvarez, Beatriz; Barutell, Lourdes; Mayayo, M Soledad; Del Castillo, Mercedes; Navarro, Emma; Malo, Fernando; Cambra, Ainhoa; López, Riánsares; Gutiérrez, M Ángel; Gutiérrez, Luisa; Boente, Carmen; Mediavilla, J Javier; Prieto, Luis; Mendo, Luis; Mansilla, M José; Ortega, Francisco Javier; Borras, Antonia; Sánchez, L Gabriel; Obaya, J Carlos; Alonso, Margarita; García, Francisco; Gutiérrez, Ángela Trinidad; Hernández, Ana M; Suárez, Dulce; Álvarez, J Carlos; Sáenz, Isabel; Martínez, F Javier; Casorrán, Ana; Ripoll, Jazmín; Salanova, Alejandro; Marín, M Teresa; Gutiérrez, Félix; Innerárity, Jaime; Álvarez, M Del Mar; Artola, Sara; Bedoya, M Jesús; Poveda, Santiago; Álvarez, Fernando; Brito, M Jesús; Iglesias, Rosario; Paniagua, Francisca; Nogales, Pedro; Gómez, Ángel; Rubio, José Félix; Durán, M Carmen; Sagredo, Julio; Gijón, M Teresa; Rollán, M Ángeles; Pérez, Pedro P; Gamarra, Javier; Carbonell, Francisco; García-Giralda, Luis; Antón, J Joaquín; de la Flor, Manuel; Martínez, Rosario; Pardo, José Luis; Ruiz, Antonio; Plana, Raquel; Macía, Ramón; Villaró, Mercè; Babace, Carmen; Torres, José Luis; Blanco, Concepción; Jurado, Ángeles; Martín, José Luis; Navarro, Jorge; Sanz, Gloria; Colas, Rafael; Cordero, Blanca; de Castro, Cristina; Ibáñez, Mercedes; Monzón, Alicia; Porta, Nuria; Gómez, María Del Carmen; Llanes, Rafael; Rodríguez, J José; Granero, Esteban; Sánchez, Manuel; Martínez, Juan; Ezkurra, Patxi; Ávila, Luis; de la Sen, Carlos; Rodríguez, Antonio; Buil, Pilar; Gabriel, Paula; Roura, Pilar; Tarragó, Eduard; Mundet, Xavier; Bosch, Remei; González, J Carles; Bobé, M Isabel; Mata, Manel; Ruiz, Irene; López, Flora; Birules, Marti; Armengol, Oriol; de Miguel, Rosa Mar; Romera, Laura; Benito, Belén; Piulats, Neus; Bilbeny, Beatriz; Cabré, J José; Cos, Xavier; Pujol, Ramón; Seguí, Mateu; Losada, Carmen; de Santiago, A María; Muñoz, Pedro; Regidor, Enrique

    2017-08-05

    Some anthropometric measurements show a greater capacity than others to identify the presence of cardiovascular risk factors. This study estimated the magnitude of the association of different anthropometric indicators of obesity with hypertension, dyslipidemia, and prediabetes (altered fasting plasma glucose and/or glycosylated hemoglobin). Cross-sectional analysis of information collected from 2022 participants in the PREDAPS study (baseline phase). General obesity was defined as body mass index ≥ 30kg/m(2) and abdominal obesity was defined with 2 criteria: a) waist circumference (WC) ≥ 102cm in men/WC ≥ 88cm in women, and b) waist-height ratio (WHtR) ≥ 0.55. The magnitude of the association was estimated by logistic regression. Hypertension showed the strongest association with general obesity in women (OR, 3.01; 95%CI, 2.24-4.04) and with abdominal obesity based on the WHtR criterion in men (OR, 3.65; 95%CI, 2.66-5.01). Hypertriglyceridemia and low levels of high-density lipoprotein cholesterol showed the strongest association with abdominal obesity based on the WHtR criterion in women (OR, 2.49; 95%CI, 1.68-3.67 and OR, 2.70; 95%CI, 1.89-3.86) and with general obesity in men (OR, 2.06; 95%CI, 1.56-2.73 and OR, 1.68; 95%CI, 1.21-2.33). Prediabetes showed the strongest association with abdominal obesity based on the WHtR criterion in women (OR, 2.48; 95%CI, 1.85-3.33) and with abdominal obesity based on the WC criterion in men (OR, 2.33; 95%CI, 1.75-3.08). Abdominal obesity indicators showed the strongest association with the presence of prediabetes. The association of anthropometric indicators with hypertension and dyslipidemia showed heterogeneous results. Copyright © 2017 Sociedad Española de Cardiología. Published by Elsevier España, S.L.U. All rights reserved.

  9. The Association between Infections and General Cognitive Ability in Young Men - A Nationwide Study.

    Directory of Open Access Journals (Sweden)

    Michael Eriksen Benros

    Full Text Available Infections and activated immune responses can affect the brain through several pathways that might also affect cognition. However, no large-scale study has previously investigated the effect of infections on the general cognitive ability in the general population.Danish nationwide registers were linked to establish a cohort of all 161,696 male conscripts during the years 2006-2012 who were tested for cognitive ability, which was based on logical, verbal, numerical and spatial reasoning at a mean age of 19.4 years. Test scores were converted to a mean of 100.00 and with a standard deviation (SD of 15. Data were analyzed as a cohort study with severe infections requiring hospitalization as exposure using linear regression.Adjusted effect sizes were calculated with non-exposure to severe infections as reference, ranging from 0.12 SD to 0.63 SD on general cognitive ability. A prior infection was associated with significantly lower cognitive ability by a mean of 1.76 (95%CI: -1.92 to -1.61; corresponding to 0.12 SD. The cognitive ability was affected the most by the temporal proximity of the last infection (P<0.001 and by the severity of infection measured by days of admission (P<0.001. The number of infections were associated with decreased cognitive ability in a dose-response relationship, and highest mean differences were found for ≥10 hospital contacts for infections (Mean: -5.54; 95%CI: -7.20 to -3.89; corresponding to 0.37 SD, and for ≥5 different types of infections (Mean: -9.44; 95%CI: -13.2 to -5.69; corresponding to 0.63 SD. Hospital contacts with infections had occurred in 35% of the individuals prior to conscription.Independent of a wide range of possible confounders, significant associations between infections and cognitive ability were observed. Infections or related immune responses might directly affect the cognitive ability; however, associated heritable and environmental factors might also account for the lowered cognitive

  10. The Association between Infections and General Cognitive Ability in Young Men - A Nationwide Study.

    Science.gov (United States)

    Benros, Michael Eriksen; Sørensen, Holger Jelling; Nielsen, Philip Rising; Nordentoft, Merete; Mortensen, Preben Bo; Petersen, Liselotte

    2015-01-01

    Infections and activated immune responses can affect the brain through several pathways that might also affect cognition. However, no large-scale study has previously investigated the effect of infections on the general cognitive ability in the general population. Danish nationwide registers were linked to establish a cohort of all 161,696 male conscripts during the years 2006-2012 who were tested for cognitive ability, which was based on logical, verbal, numerical and spatial reasoning at a mean age of 19.4 years. Test scores were converted to a mean of 100.00 and with a standard deviation (SD) of 15. Data were analyzed as a cohort study with severe infections requiring hospitalization as exposure using linear regression. Adjusted effect sizes were calculated with non-exposure to severe infections as reference, ranging from 0.12 SD to 0.63 SD on general cognitive ability. A prior infection was associated with significantly lower cognitive ability by a mean of 1.76 (95%CI: -1.92 to -1.61; corresponding to 0.12 SD). The cognitive ability was affected the most by the temporal proximity of the last infection (P<0.001) and by the severity of infection measured by days of admission (P<0.001). The number of infections were associated with decreased cognitive ability in a dose-response relationship, and highest mean differences were found for ≥10 hospital contacts for infections (Mean: -5.54; 95%CI: -7.20 to -3.89; corresponding to 0.37 SD), and for ≥5 different types of infections (Mean: -9.44; 95%CI: -13.2 to -5.69; corresponding to 0.63 SD). Hospital contacts with infections had occurred in 35% of the individuals prior to conscription. Independent of a wide range of possible confounders, significant associations between infections and cognitive ability were observed. Infections or related immune responses might directly affect the cognitive ability; however, associated heritable and environmental factors might also account for the lowered cognitive ability.

  11. Overlap between Headache, Depression, and Anxiety in General Neurological Clinics: A Cross-sectional Study

    Institute of Scientific and Technical Information of China (English)

    Cui-Bai Wei; Jian-Ping Jia; Fen Wang; Ai-Hong Zhou; Xiu-Mei Zuo; Chang-Biao Chu

    2016-01-01

    Background:Many studies have reported that depression and anxiety have bidirectional relationship with headache.However,few researches investigated the roles of depression or anxiety in patients with headache.We surveyed the prevalence of depression and anxiety as a complication or cause of headache among outpatients with a chief complaint of headache at neurology clinics in general hospitals.Additional risk factors for depression and anxiety were also analyzed.Methods:A cross-sectional study was conducted at 11 general neurological clinics.All consecutive patients with a chief complaint of headache were enrolled.Diagnoses of depression and anxiety were made using the Chinese version of the Mini International Neuropsychiatric Interview,and those for headache were made according to the International Classification of Headache Disorders,2nd Edition.The headache impact test and an 11-point verbal rating scale were applied to assess headache severity and intensity.Logistic regression was used to analyze risk factors of patients with headache for depression or anxiety.Results:A total of 749 outpatients with headache were included.Among them,148 (19.7%) were diagnosed with depression and 103 (13.7%) with anxiety.Further analysis showed that 114 (15.2%) patients complaining headache due to somatic symptoms of psychiatric disorders and 82 (10.9%) had a depression or anxiety comorbidity with headache.Most patients with depression or anxiety manifested mild to moderate headaches.Poor sleep and severe headache-related disabilities were predictors for either depression or anxiety.Conclusion:Clinicians must identify the etiology of headache and recognize the effects of depression or anxiety on headache to develop specific treatments.

  12. Work motivation, task delegation and job satisfaction of general practice staff: a cross-sectional study.

    Science.gov (United States)

    Riisgaard, Helle; Søndergaard, Jens; Munch, Maria; Le, Jette V; Ledderer, Loni; Pedersen, Line B; Nexøe, Jørgen

    2017-04-01

    Recent research has shown that a high degree of task delegation is associated with the practise staff's overall job satisfaction, and this association is important to explore since job satisfaction is related to medical as well as patient-perceived quality of care. This study aimed: (1) to investigate associations between degrees of task delegation in the management of chronic disease in general practice, with chronic obstructive pulmonary disease (COPD) as a case and the staff's work motivation, (2) to investigate associations between the work motivation of the staff and their job satisfaction. The study was based on a questionnaire to which 621 members of the practice staff responded. The questionnaire consisted of a part concerning degree of task delegation in the management of COPD in their respective practice and another part being about their job satisfaction and motivation to work. In the first analysis, we found that 'maximal degree' of task delegation was significantly associated with the staff perceiving themselves to have a large degree of variation in tasks, odds ratio (OR) = 4.26, confidence interval (CI) = 1.09, 16.62. In the second analysis, we found that this perceived large degree of variation in tasks was significantly associated with their overall job satisfaction, OR = 2.81, confidence interval = 1.71, 4.61. The results suggest that general practitioners could delegate highly complex tasks in the management of COPD to their staff without influencing the staff's work motivation, and thereby their job satisfaction, negatively, as long as they ensure sufficient variation in the tasks.

  13. Malaysian private general practitioners' views and experiences on continuous professional development: A qualitative study.

    Science.gov (United States)

    Abdul Samad, N; Md Zain, A; Osman, R; Lee, P Y; Ng, C J

    2014-01-01

    Continuous professional development (CPD) is an important aspect of a medical practitioner's career. AIMing to be at par with other developed countries for high quality of professional practice, Malaysia is planning to implement compulsory CPD for the doctors. The aim of the study was to explore the private general practitioners' (GPs) views, experiences and needs regarding CPD programme in the primary care service. This study used a qualitative methodology. Seven semi-structured interviews and three focus group discussions were conducted with private general practitioners from an urban area of Malaysia between January and December 2012. An interview topic guide was developed based on literature review and researchers' discussions and it was used to guide the interviews. All the interviews were audio-recorded, transcribed verbatim and the transcripts formed the data for analysis using the thematic approach. GPs undertook a wide range of CPD programmes to keep up with medical advances, meet patients' expectations and improve financial rewards. Conferences, lectures and online recourses were the most mentioned methods of keeping updated. Some of the GPs felt that peer motivation and networking seem to motivate and facilitate participation in CPD programmes. However, they were wary of the validity and relevance of some CPD programmes, particularly those related to pharmaceutical industry. Although the participants agreed to the new mandatory CPD regulation, they voiced concerns on how it would be implemented and wished for a more effective method of monitoring. Organised peer support and relevant CPD content may improve GP participation in CPD but adequate regulatory measure should be in place to monitor the CPD activities.

  14. The patient, the doctor, and the patient's loyalty: a qualitative study in French general practice.

    Science.gov (United States)

    Gérard, Laura; François, Mathilde; de Chefdebien, Marine; Saint-Lary, Oliver; Jami, Alain

    2016-11-01

    The term loyalty can be defined as the attachment that characterises someone who consistent in their feelings, affections, or habits. By introducing the Declaration of General Practitioner (or preferred doctor declaration) in 2004, France adopted a formal incentive for patients to be faithful to their doctor since it entailed optimal coverage of medical care by their national health insurance There has been no research evaluating the impact of this measure and to determine the components of doctor-patient loyalty. To explore what builds and maintains patients' loyalty to their GP. Qualitative study based on semi-structured interviews close to Paris (the département of Yvelines'), France. Twenty-eight patients were interviewed in five surgeries of self-employed GPs with different demographics. Interviews were transcribed and a thematic analysis conducted to categorise the data. Phenomenological analysis was used to analyse the transcripts. Patient loyalty is based mainly on trust. Trust can be reinforced by certain comforting factors such as the ability to listen, a sense of carefulness, and the quality of care. Loyalty is both a dynamic construct and a relational exchange subject to various influences. Patients find advantages in being loyal. The model of the 'family doctor' has always been the archetype of loyalty for several generations within one family. A GP's inability to meet all of the patient's requirements is not necessarily a determining factor in breaking the patient's loyalty. Loyalty is more complex than commonly assumed and involves dimensions of trust, listening, quality of care, availability, and familiarity. The observations drawn out from this study warrant a larger scale investigation. © British Journal of General Practice 2016.

  15. A STUDY OF INCID ENCE OF AWARENESS IN GENERAL AN ESTHESIA WITH INHALATIONAL AGENT (HALOTHANE

    Directory of Open Access Journals (Sweden)

    Sreeraghu

    2014-01-01

    Full Text Available BACKGROUND AND OBJECTIVES : A wareness during general anesthesia is a frightening experience , which may result in serious emotional injury and post - traumatic disorders. Awareness have been reported with many anesthetic techniques , particularly surgical patient populations such as thos e requiring anesthesia for Obstetrics , Major trauma , and cardiac surgery are known to experience a high incidence ( 7 - 43% of awareness. In our study we have made an attempt to evaluate the incidence of awareness in surgical patients under general anesthesi a using inhalational agent ( Halothane with Nitrous oxide . In this study we have evaluated the incidence of awareness by using Blood Pressure , Heart Rate , Sweating , Tears score intraoperatively and interviewing patients post - operatively by standard questio nnaire . MATERIALS AND METHODS : Hundred patients undergoing surgical procedures under general Anesthesia were randomly selected for the study . They were posted to undergo surgery from November 2011 to July 2013 . Parameters observed : Intra - operatively Blood Pressure , Heart Rate , Sweating , Tears scoring was done at 0 minutes in the operation theatre before induction and 10 minutes after intubation and monitored every 10 minutes till the end of surgery. All the patients were interviewed in the post - operative pe riod soon after complete recovery and 24 hours later again with a set of 10 questions ( Questionnaire method . RESULTS : In our study we have a standard interview questionnaire in the post operative period to study the incidence of awareness. We found that n one of the patients had conscious recall of the events during surgery. In our study of 100 patients none of the patients had awareness. Injection atropine 20 mcg/kg body weight and injection pethidine 1mg/kg body weight were given as premedication. Inducti on agent used was injection thiopental sodium 5mg/kg body weight and maintained with Nitrous oxide , Halothane as

  16. Exploring the beliefs of persisting secondary science teachers in general induction programs: A longitudinal study

    Science.gov (United States)

    Wong, Sissy Sze-Mun

    Experienced, prepared, and fully certified teachers have been related with higher student achievement, but teacher retention has been a challenge for many decades, especially retention of secondary science teachers. In order to support teachers and student learning, it is critical to understand what impacts secondary science teachers' decisions to persist in the field. This mixed methods study explored whether teacher beliefs were related to persistence over a three-year period. Participants were beginning secondary science teachers that participated in general induction programs provided by their school or district. These participants were selected due to their representative nature of the average beginning secondary science teacher in the United States. Participants' responses to annual semi-structured interviews were the source of data. Findings from quantitative and qualitative analyses revealed that the persisting teachers' beliefs remained stable over the three-year period. Quantitative analyses also revealed that there were no prevalent beliefs among the persisting teachers, even when the variables of gender and socioeconomic status of their schools were considered. When persisting teachers' beliefs about teaching and beliefs about learning were quantitatively analyzed, no relationship was found. Case study of one persisting teacher and one non-persisting teacher revealed that personal experiences and knowledge impacted their beliefs about teaching and learning. The persisting teacher that participated in inquiry-based experiences held student-centered beliefs, while the non-persisting teacher that participated in verification-type experiences held teacher-centered beliefs. This study contributes to the field of science education by examining science teacher persistence instead of attrition. It focused specifically on secondary science teachers while exploring their beliefs longitudinally. Implications from this study calls for teacher beliefs to be

  17. Pain, power and patience - A narrative study of general practitioners' relations with chronic pain patients

    Directory of Open Access Journals (Sweden)

    Troein Margareta

    2011-05-01

    Full Text Available Abstract Background Chronic pain patients are common in general practice. In this study "chronic pain" is defined as diffuse musculoskeletal pain not due to inflammatory diseases or cancer. Effective patient-physician relations improve treatment results. The relationship between doctors and chronic pain patients is often dysfunctional. Consultation training for physicians and medical students can improve the professional ability to build effective relations, but this demands a thorough understanding of the problems in the relation. Several studies have defined the issues that frequently cause problems, but few have described the process. The aim of this study was to understand and illustrate what GPs' experience in contact with chronic pain patients and what works and does not work in these consultations. Methods Our theoretical perspective is constructivist, based upon the relativist view that individuals construct realities to understand and navigate the world. Five Swedish General Practitioners (GPs, two male and three female, were interviewed and asked to tell a story about a difficult encounter with a chronic pain patient. Tapes of the interviews were transcribed and analysed using narrative analysis. Three GPs told narratives suited for our analytic tools and these were included in the final results. Results Each narrative highlights a certain dilemma and a strategy. The dilemmas were: power game; good intentions that fail when a patient is persuaded against her own conviction; persuasion of the unwilling; transferred tiredness; distrust and dissociation from the patient. Professional strategies of listening, encouraging and teamwork were central to handling difficult situations. Conclusions The narratives show that GP's consultations with chronic pain patients sometimes are characterized by conflicts and difficult situations. They are facilitated by methods such as active listening and teamwork, but still may remain hard to handle. This

  18. UNV503 full course latest  [ all discussions and all assignments

    OpenAIRE

    Laynebaril

    2017-01-01

    UNV503 full course latest  [ all discussions and all assignments ] Click Link Below To Buy: http://hwcampus.com/shop/unv503-full-course-latest/     Grand Canyon UNV503 Module1 DQ1 , DQ2 & DQ3 Latest 2015 OctoberDQ 1How do you think your graduate educational experience will be different from your undergraduate experience? How would you describe a graduate learning community? What would be the key components of a learning community and how might it be different from an u...

  19. The GEISA Spectroscopic Database System in its latest Edition

    Science.gov (United States)

    Jacquinet-Husson, N.; Crépeau, L.; Capelle, V.; Scott, N. A.; Armante, R.; Chédin, A.

    2009-04-01

    GEISA (Gestion et Etude des Informations Spectroscopiques Atmosphériques: Management and Study of Spectroscopic Information)[1] is a computer-accessible spectroscopic database system, designed to facilitate accurate forward planetary radiative transfer calculations using a line-by-line and layer-by-layer approach. It was initiated in 1976. Currently, GEISA is involved in activities related to the assessment of the capabilities of IASI (Infrared Atmospheric Sounding Interferometer on board the METOP European satellite -http://earth-sciences.cnes.fr/IASI/)) through the GEISA/IASI database[2] derived from GEISA. Since the Metop (http://www.eumetsat.int) launch (October 19th 2006), GEISA/IASI is the reference spectroscopic database for the validation of the level-1 IASI data, using the 4A radiative transfer model[3] (4A/LMD http://ara.lmd.polytechnique.fr; 4A/OP co-developed by LMD and Noveltis with the support of CNES). Also, GEISA is involved in planetary research, i.e.: modelling of Titan's atmosphere, in the comparison with observations performed by Voyager: http://voyager.jpl.nasa.gov/, or by ground-based telescopes, and by the instruments on board the Cassini-Huygens mission: http://www.esa.int/SPECIALS/Cassini-Huygens/index.html. The updated 2008 edition of GEISA (GEISA-08), a system comprising three independent sub-databases devoted, respectively, to line transition parameters, infrared and ultraviolet/visible absorption cross-sections, microphysical and optical properties of atmospheric aerosols, will be described. Spectroscopic parameters quality requirement will be discussed in the context of comparisons between observed or simulated Earth's and other planetary atmosphere spectra. GEISA is implemented on the CNES/CNRS Ether Products and Services Centre WEB site (http://ether.ipsl.jussieu.fr), where all archived spectroscopic data can be handled through general and user friendly associated management software facilities. More than 350 researchers are

  20. Comparison of dark energy models:A perspective from the latest observational data

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    We compare some popular dark energy models under the assumption of a flat universe by using the latest observational data including the type Ia supernovae Constitution compilation,the baryon acoustic oscillation measurement from the Sloan Digital Sky Survey,the cosmic microwave background measurement given by the seven-year Wilkinson Microwave Anisotropy Probe observations and the determination of H0 from the Hubble Space Telescope.Model comparison statistics such as the Bayesian and Akaike information criteria are applied to assess the worth of the models.These statistics favor models that give a good fit with fewer parameters.Based on this analysis,we find that the simplest cosmological constant model that has only one free parameter is still preferred by the current data.For other dynamical dark energy models,we find that some of them,such as the αdark energy,constant w,generalized Chaplygin gas,Chevalliear-Polarski-Linder parametrization,and holographic dark energy models,can provide good fits to the current data,and three of them,namely,the Ricci dark energy,agegraphic dark energy,and Dvali-Gabadadze-Porrati models,are clearly disfavored by the data.

  1. Drug resistance in multiple myeloma: latest findings and new concepts on molecular mechanisms

    Science.gov (United States)

    Abdi, Jahangir; Chen, Guoan; Chang, Hong

    2013-01-01

    In the era of new and mostly effective therapeutic protocols, multiple myeloma still tends to be a hard-to-treat hematologic cancer. This hallmark of the disease is in fact a sequel to drug resistant phenotypes persisting initially or emerging in the course of treatment. Furthermore, the heterogeneous nature of multiple myeloma makes treating patients with the same drug challenging because finding a drugable oncogenic process common to all patients is not yet feasible, while our current knowledge of genetic/epigenetic basis of multiple myeloma pathogenesis is outstanding. Nonetheless, bone marrow microenvironment components are well known as playing critical roles in myeloma tumor cell survival and environment-mediated drug resistance happening most possibly in all myeloma patients. Generally speaking, however; real mechanisms underlying drug resistance in multiple myeloma are not completely understood. The present review will discuss the latest findings and concepts in this regard. It reviews the association of important chromosomal translocations, oncogenes (e.g. TP53) mutations and deranged signaling pathways (e.g. NFκB) with drug response in clinical and experimental investigations. It will also highlight how bone marrow microenvironment signals (Wnt, Notch) and myeloma cancer stem cells could contribute to drug resistance in multiple myeloma. PMID:24327604

  2. Maintaining capacity for in-practice teaching and supervision of students and general practice trainees: a cross-sectional study of early career general practitioners.

    Science.gov (United States)

    Catzikiris, Nigel; Tapley, Amanda; Morgan, Simon; Holliday, Elizabeth G; Ball, Jean; Henderson, Kim; Elliott, Taryn; Spike, Neil; Regan, Cathy; Magin, Parker

    2017-08-10

    Objectives Expanding learner cohorts of medical students and general practitioner (GP) vocational trainees and the impending retirement of the 'baby boomer' GP cohort threaten the teaching and supervisory capacity of the Australian GP workforce. Engaging newly qualified GPs is essential to sustaining this workforce training capacity. The aim of the present study was to establish the prevalence and associations of in-practice clinical teaching and supervision in early career GPs.Methods The present study was a cross-sectional questionnaire-based study of recent (within 5 years) alumni of three of Australia's 17 regional general practice training programs. The outcome factor was whether the alumnus taught or supervised medical students, GP registrars or other learners in their current practice. Logistic regression analysis was used to establish associations of teaching and supervision with independent variables comprising alumnus demographics, current practice characteristics and vocational training experiences.Results In all, 230 alumni returned questionnaires (response rate 37.4%). Of currently practising alumni, 52.4% (95% confidence interval (CI) 45.6-59.0%) reported current teaching or supervisory activities. Factors significantly (Pcareer GPs in practice-based apprenticeship-like teaching or training should inform strategies to maintain workforce training capacity.What is known about the topic? Projected changes in the demand for and supply of clinical teaching and supervision within Australian general practice will require greater uptake of teaching and supervision by recently qualified GPs to ensure sustainability of this teaching model. Although interest in and undertaking of teaching roles have been documented for GP or family medicine trainees, studies investigating the engagement in these clinical roles by GPs during their early post-training period are lacking.What does this paper add? This paper is the first to document the prevalence of teaching and

  3. Impaired Fertility Associated with Subclinical Hypothyroidism and Thyroid Autoimmunity: The Danish General Suburban Population Study

    Directory of Open Access Journals (Sweden)

    Anne-Dorthe Feldthusen

    2015-01-01

    Full Text Available Introduction. The aim of this study was to estimate the significance of TSH, thyroid peroxidase antibody (TPOAb, and mild (subclinical hypothyroidism in women from The Danish General Suburban Population Study (GESUS on the number of children born, the number of pregnancies, and the number of spontaneous abortions. Methods. Retrospective cross sectional study of 11254 women participating in GESUS. Data included biochemical measurements and a self-administrated questionnaire. Results. 6.7% had mild (subclinical hypothyroidism and 9.4% prevalent hypothyroidism. In women with mild hypothyroidism TPOAb was significantly elevated and age at first child was older compared to controls. TSH and TPOAb were negatively linearly associated with the number of children born and the number of pregnancies in the full cohort in age-adjusted and multiadjusted models. TSH or TPOAb was not associated with spontaneous abortions. Mild (subclinical hypothyroidism was associated with a risk of not having children and a risk of not getting pregnant in age-adjusted and multiadjusted models. Prevalent hypothyroidism was not associated with the number of children born, the number of pregnancies, or spontaneous abortions. Conclusion. Impaired fertility is associated with TSH, TPOAb, and mild (subclinical hypothyroidism in a Danish population of women.

  4. Impaired Fertility Associated with Subclinical Hypothyroidism and Thyroid Autoimmunity: The Danish General Suburban Population Study.

    Science.gov (United States)

    Feldthusen, Anne-Dorthe; Pedersen, Palle L; Larsen, Jacob; Toft Kristensen, Tina; Ellervik, Christina; Kvetny, Jan

    2015-01-01

    The aim of this study was to estimate the significance of TSH, thyroid peroxidase antibody (TPOAb), and mild (subclinical) hypothyroidism in women from The Danish General Suburban Population Study (GESUS) on the number of children born, the number of pregnancies, and the number of spontaneous abortions. Retrospective cross sectional study of 11254 women participating in GESUS. Data included biochemical measurements and a self-administrated questionnaire. 6.7% had mild (subclinical) hypothyroidism and 9.4% prevalent hypothyroidism. In women with mild hypothyroidism TPOAb was significantly elevated and age at first child was older compared to controls. TSH and TPOAb were negatively linearly associated with the number of children born and the number of pregnancies in the full cohort in age-adjusted and multiadjusted models. TSH or TPOAb was not associated with spontaneous abortions. Mild (subclinical) hypothyroidism was associated with a risk of not having children and a risk of not getting pregnant in age-adjusted and multiadjusted models. Prevalent hypothyroidism was not associated with the number of children born, the number of pregnancies, or spontaneous abortions. Impaired fertility is associated with TSH, TPOAb, and mild (subclinical) hypothyroidism in a Danish population of women.

  5. [Musculoskeletal chronic pains and Vitamin D deficiency. Study before after in general practice].

    Science.gov (United States)

    Le Goaziou, Marie-France; Bodier, Edwige; Souweine, Gilbert; Moreau, Alain; Perdrix, Corinne; Flori, Marie; Dupraz, Christian

    2013-04-01

    The objective of this study was to evaluate the effect of the correction of vitamin D deficiency (defined by a rate≤50 nmol/l) on the pain, fatigue and quality of life. A pragmatic prospective study was conducted in Rhone-Alpes area, in general practices between February 1 and April 30, 2009. All patients aged 18 to 50 years consulting for diffuse musculoskeletal pain and/or chronic unexplained fatigue, with the only abnormality deficient serum vitamin D were enrolled in this study. They might agree to complete questionnaires on quality of life, pain assessment and control their vitamin D levels after treatment. Forty-nine complete records were analyzed. The deficiency was severe (mean 26 nmol/l). High doses of vitamin were necessary to correct deficiency, between 400,000 to 600,000 units. The correction of vitamin D deficiency resulted in a significant decrease in the level of pain intensity according to verbal rating scale (P=0.034) and the Digital Scale (Pshopping, cleaning, walking for more than a kilometer (P<0.001) and dressing (P=0.012). The correction has had a positive impact both physical, mental and social activities. Non-specific musculoskeletal pain or unexplained asthenia are common in primary care. Make a dosage of vitamin D and correct deficits is a necessity before performing complex and expensive examinations. Copyright © 2013 Elsevier Masson SAS. All rights reserved.

  6. A general stochastic model for studying time evolution of transition networks

    Science.gov (United States)

    Zhan, Choujun; Tse, Chi K.; Small, Michael

    2016-12-01

    We consider a class of complex networks whose nodes assume one of several possible states at any time and may change their states from time to time. Such networks represent practical networks of rumor spreading, disease spreading, language evolution, and so on. Here, we derive a model describing the dynamics of this kind of network and a simulation algorithm for studying the network evolutionary behavior. This model, derived at a microscopic level, can reveal the transition dynamics of every node. A numerical simulation is taken as an "experiment" or "realization" of the model. We use this model to study the disease propagation dynamics in four different prototypical networks, namely, the regular nearest-neighbor (RN) network, the classical Erdös-Renyí (ER) random graph, the Watts-Strogátz small-world (SW) network, and the Barabási-Albert (BA) scalefree network. We find that the disease propagation dynamics in these four networks generally have different properties but they do share some common features. Furthermore, we utilize the transition network model to predict user growth in the Facebook network. Simulation shows that our model agrees with the historical data. The study can provide a useful tool for a more thorough understanding of the dynamics networks.

  7. Gaining insight into benzodiazepine prescribing in General Practice in France: a data-based study

    Directory of Open Access Journals (Sweden)

    Marc Le Vaillant

    2011-05-01

    Full Text Available Abstract Background In recent decades, benzodiazepine (BZD prescriptions have been called into question in most European countries by physicians and health authorities alike, and guidelines on medical indications and treatment duration have been established to avoid long-term use and dependency. In France, many public policy measures have been implemented as BZDs are among the most prescribed medications. General practitioners (GPs were identified by the Caisse d'Assurance Maladie (the French public health insurance fund as high prescribers for these drugs. In this context, the aim of the study was to determine GPs' rates and to identify correlates of BZD and Z-drugs prescribing. Methods Data on patient characteristics, diagnoses and BZD prescriptions were drawn from French GPs' electronic medical records. These were accessed via the database which the Société Française de Médecine Générale, the French Society of General Practice, has been compiling since 1993 in a network of 90 GPs working mainly in solo practices. The participants in this network routinely register data in their daily practice. The present study examined 51,216 patients from 52 GP practices and we performed a multivariate logistic regression. The dependent variable was whether a patient was prescribed BZD at least once during 2006. Results In the present study, 12.5% of patients older than 18 were prescribed BZDs at least once during 2006 and the average (SD was 2.6 (2.4 BZD prescriptions/patient/year. The adjusted odds (confidence interval of having at least one BZD prescription were 1.20 (1.10 - 1.30 in patients older than 65; 1.05 (1.01 - 1.10 in women; 1.25 (1.17 - 1.33 in patients with associated comorbidities (cardiovascular diseases and 1.76 (1.62 - 1.92 in heavy consumers of health care (more than 4 consultations with a GP per year. Conclusions The present study showed the persistence of high rates of BZD prescription by GPs, particularly in women and older

  8. Dealing with requests for euthanasia: a qualitative study investigating the experience of general practitioners.

    Science.gov (United States)

    Georges, J-J; The, A M; Onwuteaka-Philipsen, B D; van der Wal, G

    2008-03-01

    Caring for terminally ill patients is a meaningful task, however the patient's suffering can be a considerable burden and cause of frustration. The aim of this study is to describe the experiences of general practitioners (GPs) in The Netherlands in dealing with a request for euthanasia from a terminally ill patient. The data, collected through in-depth interviews, were analysed according to the constant comparative method. Having to face a request for euthanasia when attempting to relieve a patient's suffering was described as a very demanding experience that GPs generally would like to avoid. Nearly half of the GPs (14/30) strive to avoid euthanasia or physician assisted suicide because it was against their own personal values or because it was emotional burdening to be confronted with this issue. They explained that by being directed on promoting a peaceful dying process, or the quality of end-of-life of a patient by caring and supporting the patient and the relatives it was mainly possible to shorten patient's suffering without "intentionally hastening a patient's death on his request". The other GPs (16/30) explained that as sometimes the suffering of a patient could not be lessened they were open to consider a patient's request for euthanasia or physician assisted suicide. They underlined the importance of a careful decision-making process, based on finding a balance between the necessity to shorten the patient's suffering through euthanasia and their personal values. Dealing with requests for euthanasia is very challenging for GPs, although they feel committed to alleviate a patient's suffering and to promote a peaceful death.

  9. Perioperative management of patients for osteo-odonto-kreatoprosthesis under general anaesthesia: A retrospective study

    Directory of Open Access Journals (Sweden)

    Rakesh Garg

    2011-01-01

    Full Text Available An osteo-odonto-keratoprosthesis (OOKP procedure is indicated in patients with failed corneal transplant but having intact retina for visual improvement. We studied perioperative concerns of patients who underwent the staged OOKP procedure. This was a retrospective analysis of patients who underwent OOKP. The information regarding symptoms, associated comorbidities, perioperative events including anaesthetic management were collected. Eight patients (five females and three males underwent the staged OOKP procedure. The median age was 18 years. The median weight was 45 kg. The median duration of loss of vision was 4 years. The aetiology of blindness included Stevens-Johnson′s syndrome (SJS (7 and chemical burn (1. Four patients had generalized skin problem due to SJS. All cases were managed under general anaesthesia, and airway management included nasotracheal intubation for stage I and orotracheal intubation for stage II. The median mallampati classification was I prior to OOKP stage I procedure while it changed to II at stage II procedure. Two patients required fibreoptic nasotracheal intubation. One patient had excessive oozing from the mucosal harvest site and was managed conservatively. In one patient, tooth harvesting was done twice as the first tooth was damaged during creating a hole in it. We conclude that OOKP requires multidisciplinary care. Anaesthesiologist should evaluate the airway carefully and disease-associated systemic involvements. The use of various drugs requires caution and steroid supplementation should be done. Airway difficulty should be anticipated, mandating thorough evaluation. Re-evaluation of airway is prudent as it may become difficult during the staged OOKP procedure.

  10. Laparoscopic total extraperitoneal repair under spinal anesthesia versus general anesthesia: a randomized prospective study

    OpenAIRE

    2016-01-01

    Turgut Donmez,1 Vuslat Muslu Erdem,2 Oguzhan Sunamak,3 Duygu Ayfer Erdem,2 Huseyin Imam Avaroglu1 1Department of General Surgery, 2Department of Anesthesiology and Reanimation, Lutfiye Nuri Burat State Hospital, 3Department of General Surgery, Haydarpasa Numune Training and Research Hospital, Istanbul, Turkey Background: Laparoscopic total extraperitoneal (TEP) inguinal hernia repair is a well-known approach to inguinal hernia repair that is usually performed under general anesthesia (GA). ...

  11. Course and prognosis of older back pain patients in general practice: a prospective cohort study.

    Science.gov (United States)

    Scheele, Jantine; Enthoven, Wendy T M; Bierma-Zeinstra, Sita M A; Peul, Wilco C; van Tulder, Maurits W; Bohnen, Arthur M; Berger, Marjolein Y; Koes, Bart W; Luijsterburg, Pim A J

    2013-06-01

    The aim of the current study was to determine the course of back pain in older patients and identify prognostic factors for non-recovery at 3 months' follow-up. We conducted a prospective cohort study (the BACE study) of patients aged >55 years visiting a general practitioner (GP) with a new episode of back pain in the Netherlands. The course of back pain was described in terms of self-perceived recovery, pain severity, disability, pain medication, and GP visits at 6 weeks' and 3 months' follow-up. Prognostic factors for non-recovery at 3 months' follow-up were derived from the baseline questionnaire and physical examination. Variables with a prognostic value were identified with multivariable logistic regression analysis (method backward), and an area under the receiver operating curve (AUC) was calculated for the prognostic model. A total of 675 back pain patients (mean age 66.4 (SD 7.6) years) participated in the BACE cohort study. At 6 weeks' follow-up 64% of the patients reported non-recovery from back pain. At 3 months' follow-up 61% still reported non-recovery, but only 26% of these patients had revisited the GP. Longer duration of the back pain, severity of back pain, history of back pain, absence of radiating pain in the leg below the knee, number of comorbidities, patients' expectation of non-recovery, and a longer duration of the timed 'Up and Go' test were significantly associated with non-recovery in a multiple regression model (AUC 0.79). This information can help GPs identify older back pain patients at risk for non-recovery. Copyright © 2013 International Association for the Study of Pain. Published by Elsevier B.V. All rights reserved.

  12. A General Survey of Study on Gelao - language%仡佬语研究概观

    Institute of Scientific and Technical Information of China (English)

    占升平

    2013-01-01

    仡佬语是在中国西南地区的一种濒危语言,目前作为母语使用的人口很少,但内部方言土语众多。仡佬语研究从上个世纪50年代开始,前期研究集中在系属讨论和方言分区上,20年代90年代以后重在对语言材料的挖掘和对各方言土语的全面描写上,同时国内外学者为仡央语系调查方面进行了很好的合作。通过对仡佬语研究成果进行梳理的同时,还对仡佬语研究中存在的问题提出了一些意见。%In spite of the fact that it has various internal dialects ,Gelao -languague is a highly endangered language used by Gelao Nationality in the southwest of China ,with fewer and fewer native speakers .The study of Gelao -language ,started in 1950s ,can roughly divided into two stages with 1990 as the line of demarcation .The former focused on language system quality and dialect distribution of Gelao - language .The latter concentrates on the language material analysis and descriptive study of dialects of Gelao -languague .Cooperative study of Language investigation about Ge -Yang language family has also developed .Based upon the general survey of study on Gelao -language ,the paper offers some analysis of problems existing in the study of Gelao -language .

  13. Prevalence of fragrance contact allergy in the general population of five European countries : a cross-sectional study

    NARCIS (Netherlands)

    Diepgen, T. L.; Ofenloch, R.; Bruze, M.; Cazzaniga, S.; Coenraads, P. J.; Elsner, P.; Goncalo, M.; Svensson, A.; Naldi, L.

    2015-01-01

    Background Contact allergy to fragrances is assessed mostly in clinical populations of patients. Studies in the general population are scarce and vary in their methodology across countries. Objectives To determine the prevalence of fragrance contact allergy in the European general population and to

  14. Antibiotics dispensing for URTIs by community pharmacists and general medical practitioners in Penang, Malaysia: A comparative study using simulated patients

    OpenAIRE

    Alabid, Alamin Hassan M. A.; Ibrahim, Mohamed Izham Mohamed; Hassali,Mohamed Azmi

    2014-01-01

    Background: In Malaysia, doctors in private clinics (often called dispensing doctors) are permitted to dispense medicines. This potentially may compromise rational dispensing of medicines in general and antibiotics in particular. Aim: This study explored, assessed and compared dispensing of antibiotics between Community Pharmacist (CP) and General Practitioners (GPs) regarding symptomatic diagnosis, antibiotic categories, adherence to therapeutic doses and promotion of generic antibiotics...

  15. Duration of major depressive episodes in the general population : results from The Netherlands Mental Health Survey and Incidence Study (NEMESIS)

    NARCIS (Netherlands)

    Spijker, J; De Graaf, R; Bijl, RV; Beekman, ATF; Ormel, J; Nolen, WA

    2002-01-01

    Background Data on the duration of major depressive episodes (MDE) in the general population are sparse. Aims To assess the duration of MDE and its clinical and socio-demographic determinants in a study group drawn from the general population with newly originated episodes of major depression. Metho

  16. Duration of major depressive episodes in the general population: results from The Netherlands Mental Health Survey and Incidence Study (NEMESIS)

    NARCIS (Netherlands)

    Spijker, J.J.A.; de Graaf, R.; Bijl, R.V.; Beekman, A.T.F.; Ormel, J.; Nolen, W.A.

    2002-01-01

    Background Data on the duration of major depressive episodes (MDE) in the general population are sparse. Aims To assess the duration of MDE and its clinical and socio-demographic determinants in a study group drawn from the general population with newly originated episodes of major depression. Metho

  17. Associations between repression, general maladjustment, body weight, and body shape in older males : The normative aging study

    NARCIS (Netherlands)

    Niaura, RS; Stroud, LR; Todaro, J; Ward, KD; Spiro, A; Aldwin, C; Landsberg, L; Weiss, ST

    2003-01-01

    We examined relationships between repression, general maladjustment, body mass index (BMI), and waist-to-hip ratio (WHR). The participants were 1,081 healthy older men from the Normative Aging Study. Repression and General Maladjustment Scales of the Minnesota Multiphasic Personality Inventory were

  18. A Study of General Education Astronomy Students' Understandings of Cosmology. Part I. Development and Validation of Four Conceptual Cosmology Surveys

    Science.gov (United States)

    Wallace, Colin S.; Prather, Edward E.; Duncan, Douglas K.

    2011-01-01

    This is the first in a series of five articles describing a national study of general education astronomy students' conceptual and reasoning difficulties with cosmology. In this paper, we describe the process by which we designed four new surveys to assess general education astronomy students' conceptual cosmology knowledge. These surveys focused…

  19. The General Weakness Syndrome Therapy (GymNAST) study: protocol for a cohort study on recovery on walking function.

    Science.gov (United States)

    Mehrholz, Jan; Mückel, Simone; Oehmichen, Frank; Pohl, Marcus

    2014-10-24

    Critical illness myopathy (CIM) and polyneuropathy (CIP) are common complications of critical illness that frequently occur together. Both cause so called intensive care unit (ICU)-acquired muscle weakness. This weakness of limb muscles increases morbidity and delay rehabilitation and recovery of walking ability. Although full recovery has been reported people with severe weakness may take months to improve walking. Focused physical rehabilitation of people with ICU-acquired muscle weakness is therefore of great importance. However, although physical rehabilitation is common, detailed knowledge about the pattern and the time course of recovery of walking function are not well understood. Therefore, the aim of the General Weakness Syndrome Therapy (GymNAST) study is to describe the time course of recovery of walking function and other activities of daily living in these patients. We conduct a prospective cohort study of people with ICU-acquired muscle weakness with defined diagnosis of CIM or CIP. Based on our sample size calculation, approximately 150 patients will be recruited from the ICU of our hospital in Germany. Amount and content of physical rehabilitation, clinical tests for example, muscle strength and motor function and neuropsychological assessments will be used as independent variables. The primary outcomes will include recovery of walking function and mobility. Secondary outcomes will include global motor function, activities in daily life and participation. The study is being carried out in agreement with the Declaration of Helsinki and conducted with the approval of the local medical Ethics Committee (Landesärztekammer Sachsen, Germany, reference number EK-BR-32/13-1) and with the understanding and written consent of each patient's guardian. The results of this study will be published in peer-reviewed journals and disseminated to the medical society and general public. Published by the BMJ Publishing Group Limited. For permission to use (where not

  20. Collaboration between general practitioners and mental health care professionals: a qualitative study

    Directory of Open Access Journals (Sweden)

    Haavet Ole R

    2011-05-01

    Full Text Available Abstract Background Collaboration between general practice and mental health care has been recognised as necessary to provide good quality healthcare services to people with mental health problems. Several studies indicate that collaboration often is poor, with the result that patient' needs for coordinated services are not sufficiently met, and that resources are inefficiently used. An increasing number of mental health care workers should improve mental health services, but may complicate collaboration and coordination between mental health workers and other professionals in the treatment chain. The aim of this qualitative study is to investigate strengths and weaknesses in today's collaboration, and to suggest improvements in the interaction between General Practitioners (GPs and specialised mental health service. Methods This paper presents a qualitative focus group study with data drawn from six groups and eight group sessions with 28 health professionals (10 GPs, 12 nurses, and 6 physicians doing post-doctoral training in psychiatry, all working in the same region and assumed to make professional contact with each other. Results GPs and mental health professionals shared each others expressions of strengths, weaknesses and suggestions for improvement in today's collaboration. Strengths in today's collaboration were related to common consultations between GPs and mental health professionals, and when GPs were able to receive advice about diagnostic treatment dilemmas. Weaknesses were related to the GPs' possibility to meet mental health professionals, and lack of mutual knowledge in mental health services. The results describe experiences and importance of interpersonal knowledge, mutual accessibility and familiarity with existing systems and resources. There is an agreement between GPs and mental health professionals that services will improve with shared knowledge about patients through systematic collaborative services, direct cell

  1. Latest tendency in the Antarctic ozone longitudinal distribution

    Science.gov (United States)

    Milinevsky, Gennadi; Grytsai, Asen; Klekociuk, Andrew; Evtushevsky, Olexander

    2014-05-01

    Significant ozone depletion was observed within the southern polar vortex during spring in the 1980s - early 1990s. Later, a stabilization in total ozone levels and ozone hole area has been observed. Atmosphere models predict a consequent recovery of the Antarctic ozone. Nevertheless, identification of the long-term processes is complicated by high interannual variability hiding their general regularities. In particular, a large stratosphere warming in 2002 resulted in significant increase in total ozone levels. The Antarctic ozone hole is formed inside polar stratospheric vortex, which is under influence of large-scale planetary waves. The components of the quasi-stationary wave (QSW) in the spring Southern Hemisphere (SH) stratosphere is mainly contributed by zonal wave number 1 which in turn determines the location of the total ozone extremes in spring: QSW minimum (maximum) is located in the South Atlantic (Australian) sector. In our work the satellite data of TOMS/Nimbus-7, TOMS/Earth Probe and OMI/Aura (http://ozoneaq.gsfc.nasa.gov/) have been used to investigate longitudinal distribution of the total ozone in Antarctic region. The gap in these satellite observations (1993-1995) was filled by the Multi-Sensor Reanalysis data (http://www.temis.nl/). Ozone distribution in the SH high and mid latitudes 80-50S were analyzed for southern spring season including months from September to November. The zonal distribution is considered along seven latitude circles from 80S to 50S with step of five degrees. To distinguish long-term processes and to obtain a quasi-stationary pattern, daily September - November ozone was averaged. Our previous study demonstrated a systematic eastward shift of the QSW minimum region. In this study, we extended the analysis to 2013 and obtained new results that exhibited a probable cessation in that eastward shift. Polynomial fit for all chosen latitudes is even evidence of a change in the tendency to opposite. It more time needs to

  2. Study and characterization of interfaces in a two-dimensional generalized voter model

    Science.gov (United States)

    Bordogna, Clelia M.; Albano, Ezequiel V.

    2011-04-01

    We propose and study, by means of numerical simulations, the time evolution of interfaces in a generalized voter model in d=2 dimensions. In this model, a randomly selected voter can change his or her opinion (state) with a certain probability that is an algebraic function of the average opinion of his or her nearest neighbors. By starting with well-defined (sharp) interfaces between two different states of opinion, we measure the time dependence of the interface width (w), which behaves as a power law, i.e., w∝tδ. In this way we characterized three different types of interfaces: (i) between an ordered phase (consensus) and a disordered one (δ=1/2); (ii) between ordered phases having different states of opinion (δ=1/2), which corresponds to interface coarsening without surface tension; and (iii) as in (ii) but considering surface tension. Here, we observe a finite-size induced crossover with exponents δ=1/4 and δ=1/2 for early and longer times, respectively. So, our study allows for the characterization of interfaces of quite different nature in a unified fashion, providing insight into the understanding of interface coarsening with and without surface tension.

  3. Laparoscopic cholecystectomy under spinal-epidural anesthesia vs. general anaesthesia: a prospective randomised study.

    Science.gov (United States)

    Donmez, Turgut; Erdem, Vuslat Muslu; Uzman, Sinan; Yildirim, Dogan; Avaroglu, Huseyin; Ferahman, Sina; Sunamak, Oguzhan

    2017-03-01

    Laparoscopic cholecystectomy (LC) is usually performed under the general anesthesia (GA). Aim of the study is to investigate the availability, safety and side effects of combined spinal/epidural anesthesia (CSEA) and comparison it with GA for LC. Forty-nine patients who have a LC plan were included into the study. The patients were randomly divided into GA (n = 25) and CSEA (n = 24) groups. Intraoperative and postoperative adverse events, postoperative pain levels were compared between groups. Anesthesia procedures and surgeries for all patients were successfully completed. After the organization of pneumoperitoneum in CSEA group, 3 patients suffered from shoulder pain (12.5%) and 4 patients suffered from abdominal discomfort (16.6%). All these complaints were recovered with IV fentanyl administration. Only 1 patient developed hypotension which is recovered with fluid replacement and no need to use vasopressor treatment. Postoperative shoulder pain was significantly less observed in CSEA group (25% vs. 60%). Incidence of postoperative nausea and vomiting (PONV) was less observed in CSEA group but not statistically significant (4.2% vs. 20%). In the group of CSEA, 3 patients suffered from urinary retention (12.5%) and 2 patients suffered from spinal headache (8.3%). All postoperative pain parameters except 6th hour, were less observed in CSEA group, less VAS scores and less need to analgesic treatment in CSEA group comparing with GA group. CSEA can be used safely for laparoscopic cholecystectomies. Less postoperative surgical field pain, shoulder pain and PONV are the advantages of CSEA compared to GA.

  4. Training for generalization in Theory of Mind: a study with older adults

    Directory of Open Access Journals (Sweden)

    ELENA eCAVALLINI

    2015-08-01

    Full Text Available Theory of Mind (ToM refers to the ability to attribute independent mental states to self and others in order to explain and predict social behavior. Recent research in this area has shown a decline in ToM abilities associated with normal aging that is of a moderate magnitude or greater. Very few studies have investigated whether it is possible to improve older adults’ ToM abilities.The present study was designed to address this gap in the literature by evaluating the impact of a ToM training on practiced and transfer tasks. We provided older adults with a variety of activities designed to facilitate the generalization of benefits to other ToM-demanding tasks.Participants were 63 healthy older adults, native Italian speakers (Mage = 71.44, SD = 5.24, age range: 63-81 years. Participants were randomly assigned to one of two groups: the ToM training (age range: 63-81 years and the physical-conversation training (age range: 64-81 years. Training effects were measured using the Strange Stories (practiced task and the Animation task (transfer task. Results revealed the efficacy of the training in producing improvements on practiced but also on transfer tasks.

  5. GLOBAL GENERAL RELATIVISTIC MAGNETOHYDRODYNAMIC SIMULATIONS OF BLACK HOLE ACCRETION FLOWS: A CONVERGENCE STUDY

    Energy Technology Data Exchange (ETDEWEB)

    Shiokawa, Hotaka; Dolence, Joshua C.; Gammie, Charles F. [Department of Astronomy, University of Illinois at Urbana-Champaign, 1002 West Green Street, Urbana, IL 61801 (United States); Noble, Scott C. [Center for Computational Relativity and Gravitation, School of Mathematical Sciences, Rochester Institute of Technology, Rochester, NY 14623 (United States)

    2012-01-10

    Global, general relativistic magnetohydrodynamic (GRMHD) simulations of non-radiative, magnetized disks are widely used to model accreting black holes. We have performed a convergence study of GRMHD models computed with HARM3D. The models span a factor of four in linear resolution, from 96 Multiplication-Sign 96 Multiplication-Sign 64 to 384 Multiplication-Sign 384 Multiplication-Sign 256. We consider three diagnostics of convergence: (1) dimensionless shell-averaged quantities such as plasma {beta}; (2) the azimuthal correlation length of fluid variables; and (3) synthetic spectra of the source including synchrotron emission, absorption, and Compton scattering. Shell-averaged temperature is, except for the lowest resolution run, nearly independent of resolution; shell-averaged plasma {beta} decreases steadily with resolution but shows signs of convergence. The azimuthal correlation lengths of density, internal energy, and temperature decrease steadily with resolution but show signs of convergence. In contrast, the azimuthal correlation length of magnetic field decreases nearly linearly with grid size. We argue by analogy with local models, however, that convergence should be achieved with another factor of two in resolution. Synthetic spectra are, except for the lowest resolution run, nearly independent of resolution. The convergence behavior is consistent with that of higher physical resolution local model ({sup s}hearing box{sup )} calculations and with the recent non-relativistic global convergence studies of Hawley et al.

  6. Breast augmentation under general anesthesia versus monitored anesthesia care: a retrospective comparative study.

    Science.gov (United States)

    Eldor, Liron; Weissman, Avi; Fodor, Lucian; Carmi, Nurit; Ullmann, Yehuda

    2008-09-01

    Breast augmentation is one of the leading esthetic surgeries, enjoying high satisfaction rates. Pain, nausea, and vomiting are frequent shortcomings of the immediate postoperative period. The aim of this study was to compare breast augmentation from the anesthetic point of view: general anesthesia (GA) versus monitored anesthesia care (MAC). The charts of 115 patients were reviewed in this retrospective study performed over a period of 2 years. Sixty-nine women chose to have the surgery done under MAC, and 46 under GA. Statistically significant differences were noted in both postoperative hospital stay (16.1 +/- 6.78 hours vs. 11.7 +/- 6.10 hours) and frequency of vomiting (mean, 0.5 vs. 0.22 times per patient) after GA and MAC, respectively (Mann-Whitney, P < 0.01). Postoperative pain, assessed using the visual analog scale, was significantly higher (mean visual analog scale, 5 vs. 3.27) when the prosthesis was placed in the submuscular plane compared with the subglandular plane (Mann-Whitney, P = 0.043). When offered a choice, more women preferred MAC over GA for their breast augmentation procedure. Less vomiting and shorter postoperative hospitalization were prominent in the MAC group.

  7. Urinary Analysis of Fluid Retention in the General Population: A Cross-Sectional Study

    Science.gov (United States)

    Grankvist, Nina; Krizhanovskii, Camilla

    2016-01-01

    Objective Renal conservation (retention) of fluid might affect the outcome of hospital care and can be indicated by increased urinary concentrations of metabolic waste products. We obtained a reference material for further studies by exploring the prevalence of fluid retention in a healthy population. Methods Spot urine sampling was performed in 300 healthy hospital workers. A previously validated algorithm summarized the urine-specific gravity, osmolality, creatinine, and color to a fluid retention index (FRI), where 4.0 is the cut-off for fluid retention consistent with dehydration. In 50 of the volunteers, we also studied the relationships between FRI, plasma osmolality, and water-retaining hormones. Results The cut-off for fluid retention (FRI ≥ 4.0) was reached by 38% of the population. No correlation was found between the FRI and the time of the day of urine sample collection, and the FRI was only marginally correlated with the time period spent without fluid intake. Volunteers with fluid retention were younger, generally men, and more often had albuminuria (88% vs. 34%, P dehydration is common in healthy staff working in a Swedish hospital. PMID:27764121

  8. Routine general practice care for panic disorder within the lifestyle approach to managing panic study

    Directory of Open Access Journals (Sweden)

    Rodney A. Lambert

    2012-07-01

    Full Text Available Routine general practice (GP care is rarely comprehensively described in clinical trials. This paper examines routine GP care within the lifestyle approach to managing panic (LAMP study. The aim of this paper is to describe/discuss routine GP care for panic disorder (PD patients within both study arms in the LAMP study. An unblinded pragmatic randomised controlled trial in 15 East of England GP practices (2 primary care trusts. Participants met Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition criteria for PD with/without agoraphobia. Follow-up measures recorded at 20 weeks/10 months following randomisation. Control arm, unrestricted routine GP care (practice appointments, referrals and prescriptions. Trial arm, occupational therapyled lifestyle treatment comprising lifestyle review of fluid intake, diet pattern, exercise, caffeine, alcohol and nicotine. Primary outcome measure: beck anxiety inventory. At baseline, participants attended 2-3 times more GP appointments than population average, reducing at 10 months to 1.6 times population average for routine GP care and 0.97 population average for lifestyle arm. At 10 months, 33% fewer referrals (6 referrals; 0 mental health than at baseline (9 referrals; 2 mental health were made for lifestyle arm patients compared with 42% increase (from 12 referrals; 8 mental health at baseline to 17 referrals; 7 mental health in GP care arm. Selective serotonin reuptake inhibitors were prescribed most often. Benzodiazepines and beta-blockers were prescribed more often than tricyclic against current clinical guidelines. In conclusion, we found that PD patients at baseline were high healthcare resource users. Treatment in both study arms reduced resource use. Routine GP care requires further review for this patient group.

  9. Pediatricians' awareness of diagnostic medical radiation effects and doses: are the latest efforts paying off?

    National Research Council Canada - National Science Library

    Ayse Seçil Eksioglu; Çigdem Üner

    .... We assessed the current understanding of radiation doses and risks among a sample group of pediatricians and evaluated whether the latest efforts to improve radiation awareness affected the results...

  10. Mulptiple Sclerosis, Symptoms, Diagnosis, Treatment and Latest NIH Research | NIH MedlinePlus the Magazine

    Science.gov (United States)

    ... turn Javascript on. Feature: Multiple Sclerosis Multiple Sclerosis: Symptoms, Diagnosis, Treatment and Latest NIH Research Past Issues / Spring 2012 Table of Contents Symptoms Multiple sclerosis (MS) is an unpredictable disease. MS ...

  11. Balancing Generalization and Lexical Conservatism: An Artificial Language Study with Child Learners

    Science.gov (United States)

    Wonnacott, Elizabeth

    2011-01-01

    Successful language acquisition involves generalization, but learners must balance this against the acquisition of lexical constraints. Such learning has been considered problematic for theories of acquisition: if learners generalize abstract patterns to new words, how do they learn lexically-based exceptions? One approach claims that learners use…

  12. General Personality Disorder: A study into the core components of personality pathology

    NARCIS (Netherlands)

    Berghuis, H.

    2014-01-01

    This thesis explores the structure of various models of General Personality Disorder (PD) and severity levels of PD. In the first part of this thesis, a model of functional impairment, i.e. Livesley's adaptive failure model, as a definition of General PD, and a model of structural impairment, i.e. K

  13. Generalized equations for estimating DXA percent fat of diverse young women and men: The Tiger Study

    Science.gov (United States)

    Popular generalized equations for estimating percent body fat (BF%) developed with cross-sectional data are biased when applied to racially/ethnically diverse populations. We developed accurate anthropometric models to estimate dual-energy x-ray absorptiometry BF% (DXA-BF%) that can be generalized t...

  14. Balancing Generalization and Lexical Conservatism: An Artificial Language Study with Child Learners

    Science.gov (United States)

    Wonnacott, Elizabeth

    2011-01-01

    Successful language acquisition involves generalization, but learners must balance this against the acquisition of lexical constraints. Such learning has been considered problematic for theories of acquisition: if learners generalize abstract patterns to new words, how do they learn lexically-based exceptions? One approach claims that learners use…

  15. Xanthelasmata, arcus corneae, and ischaemic vascular disease and death in general population: prospective cohort study

    DEFF Research Database (Denmark)

    Christoffersen, Mette; Frikke-Schmidt, Ruth; Schnohr, Peter

    2011-01-01

    To test the hypothesis that xanthelasmata and arcus corneae, individually and combined, predict risk of ischaemic vascular disease and death in the general population.......To test the hypothesis that xanthelasmata and arcus corneae, individually and combined, predict risk of ischaemic vascular disease and death in the general population....

  16. A Computer-Based Laboratory Project for the Study of Stimulus Generalization and Peak Shift

    Science.gov (United States)

    Derenne, Adam; Loshek, Eevett

    2009-01-01

    This paper describes materials designed for classroom projects on stimulus generalization and peak shift. A computer program (originally written in QuickBASIC) is used for data collection and a Microsoft Excel file with macros organizes the raw data on a spreadsheet and creates generalization gradients. The program is designed for use with human…

  17. General Personality Disorder: A study into the core components of personality pathology

    NARCIS (Netherlands)

    Berghuis, H.

    2014-01-01

    This thesis explores the structure of various models of General Personality Disorder (PD) and severity levels of PD. In the first part of this thesis, a model of functional impairment, i.e. Livesley's adaptive failure model, as a definition of General PD, and a model of structural impairment, i.e.

  18. Index of /data/genlibi/LATEST [Life Science Database Archive metadata

    Lifescience Database Archive (English)

    Full Text Available Index of /data/genlibi/LATEST Name Last modified Size Description Parent Directory - README.html... 25-Mar-2014 17:17 7.2K README_e.html 07-Oct-2014 13:29 6.2K genlibi.zip 25-Mar-2014 12:37 25K genlibi_en.zip 25-Mar-2014 12:37 11K Index of /data/genlibi/LATEST ...

  19. nr500 full course latest 2015 november [ all discussions and all assignments

    OpenAIRE

    Laynebaril1

    2017-01-01

     nr500 full course latest 2015 november [ all discussions and all assignments ] Click Link Below To Buy: http://hwcampus.com/shop/nr500-full-course-latest/   week 1 Strategies for Success in the Online Learning Environment (graded) Identify barriers to success in the online learning environment and the strategies to overcome the barriers. Please cite the sources used to support your response.     Scholarly Discussion (graded) What are the pri...

  20. hrm320 full course latest 2015 november [ all discussion , assignment ,week 4 quiz and research paper

    OpenAIRE

    Laynebaril1

    2017-01-01

      hrm320 full course latest 2015 november [ all discussion , assignment ,week 4 quiz and research paper Click Link Below To Buy: http://hwcampus.com/shop/hrm320-full-course-latest/   week 1   week 1   Lofty Lawns (graded) MAKE CERTAIN TO READ MY FIRST POST BEFORE POSTING YOUR DISCUSSION FOR THE WEEK! (TCO 1) Larry Land establishes a landscaping business under the name "Lofty Lawns." The business handles lawn care and seasonal flowersfor apartm...