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Sample records for gate appointment system

  1. Enhanced Leads and Appointment System

    Data.gov (United States)

    Social Security Administration — The data asset contains information on current or upcoming appointments, individuals who will be attending the appointment, potential intent to file a claim (lead),...

  2. Patient Telephone Appointment System for High Volume Primary Care Sites

    National Research Council Canada - National Science Library

    Worthington, Francine

    2000-01-01

    The purpose of this research is to design a patient telephone appointment system for use in the Naval Medical Center San Diego's high volume Primary Care sites, which will reduce variation and ensure...

  3. Pengaruh Appointment Registration System terhadap Waktu Tunggu dan Kepuasan Pasien

    Directory of Open Access Journals (Sweden)

    Yuli Susanti

    2015-02-01

    Full Text Available Abstrak Peningkatan derajat kesehatan dapat dicapai melalui kemudahan akses terhadap fasilitas kesehatan. Peningkatan peserta pada program Jaminan Kesehatan Nasional (JKN mengakibatkan antrian panjang di sarana pelayanan kesehatan. Penelitian ini bertujuan untuk menganalisis pengaruh metode appointment registration system (ARS terhadap waktu tunggu dan kepuasan pasien. Metode penelitian yang digunakan adalah survei dengan sampel 380 orang dan observasi pada bulan Desember 2014 di RS Al-Islam Bandung. Analisis menggunakan structural equation modeling (SEM dan production operation management-quantitative methods (POMQM. Hasil penelitian diperoleh kondisi pelaksanaan ARS (60,7%, waktu tunggu (59,1%, dan kepuasan pasien (67,3% termasuk dalam kategori cukup. Terdapat pengaruh positif dan signifikan ARS terhadap waktu tunggu (51,84%, pengaruh positif dan signifikan waktu tunggu terhadap kepuasan pasien (25%, dan total pengaruh ARS terhadap kepuasan pasien (16,79%. ARS dapat menurunkan waktu tunggu secara efektif tetapi tidak semua metode ARS dapat menurunkan waktu tunggu. Simpulan, pasien RS Al-Islam Bandung merasa cukup puas terhadap pendaftaran appointment dan waktu tunggu. Kata kunci: Appointment registration system, kepuasan pasien, waktu tunggu   The Influence of Outpatient Appointment Registration System to Waiting Time and Patient Satisfications Abstract Health improvement can be achieved through accessibility to health services. An increased participants in the Health Insurance Program (HIP resulted in a long queue in the hospital. This research aim was to analize influence of appointment registration system (ARS to waiting time and patient satisfaction. Research method using patient satisfaction survey in 380 subjects and observation on December 2014 at Al-Islam Bandung Hospital. The result was analyzed using structural equation modeling (SEM and production operation management-quantitative methods (POMQM. The results showed that the

  4. Disruption management for truck appointment system at a container terminal

    DEFF Research Database (Denmark)

    Li, Na; Chen, Gang; Govindan, Kannan

    2018-01-01

    Disruption often occurs in both land-side and sea-side operations at a container terminal, causing substantial interference of scheduled operations and poor green performance. The land-side disruption is rarely researched, and this paper addresses the ordinary level of such disruption where......-appointed arrivals at a container terminal that is running an appointment system. Second, we propose some response strategies to cope with different levels of disruptions, and evaluate their resilience ability with two Key Performance Indicators (KPIs): total waiting time of on-time trucks and total idling emissions...... scenarios is a combined one based on priority and yard-crane moving distance; its performance depends primarily on the concentration level of container locations and secondly on the system utilization. In the other scenarios that have low arrival punctuality, the best strategy could focus purely on yard...

  5. Patient-Reported Attributions for Missed Colonoscopy Appointments in Two Large Healthcare Systems.

    Science.gov (United States)

    Bhise, Viraj; Modi, Varsha; Kalavar, Anisha; Espadas, Donna; Hanser, Loretta; Gould, Milena; El-Serag, Hashem B; Singh, Hardeep

    2016-07-01

    Missed colonoscopy appointments (no-shows) can lead to wasted resources and delays in colorectal cancer diagnosis, an area of special concern in public health systems that often provide care for vulnerable patients. Our objective was to identify reasons for missed colonoscopy appointments in patients seeking care at two large public health systems in Houston, TX. We conducted a telephone survey of patients who missed their colonoscopy appointments at two tertiary care health systems. Using a structured survey instrument, we collected information on patient-specific and health services barriers. Patient-specific barriers included perceived procedural-related factors (e.g., difficulty in preparation), cognitive-emotional factors (e.g., fear or concern about modesty), and changes in health status (e.g., improvement or worsening of health). Health services barriers included logistical factors (e.g., travel-related difficulties) and appointment scheduling problems (inconvenient date or time). We examined differences in attributions for missed appointments between the two study sites. Of 160 unique patients (102 Site A and 58 Site B) who missed their appointment during the study period, 153 (95.6 %) attributed their no-show to at least one of the listed barriers. Most respondents (125; 78.1 %) cited travel-related issues or scheduling problems as reasons for their missed appointment. Not having a ride or a travel companion was the most commonly reported travel-related issue. We also found significant differences for barriers between the two sites. Most missed colonoscopy appointments resulted from potentially preventable travel- and scheduling-related issues. Because barriers to keeping colonoscopy appointments are different across health systems, each health system might need to develop unique interventions to reduce missed colonoscopy appointments.

  6. GATING SYSTEMS FOR PRODUCTION OF HYDRODISTRIBUTORS

    Directory of Open Access Journals (Sweden)

    D. A. Volkov

    2010-01-01

    Full Text Available Gating systems of the first group of special ways of casting into shell molds, casting in lined chill mold as more effective for production of hydrodistributors were developed and studied.

  7. Active gated imaging in driver assistance system

    Science.gov (United States)

    Grauer, Yoav

    2014-04-01

    In this paper, we shall present the active gated imaging system (AGIS) in relation to the automotive field. AGIS is based on a fast-gated camera and pulsed illuminator, synchronized in the time domain to record images of a certain range of interest. A dedicated gated CMOS imager sensor and near infra-red (NIR) pulsed laser illuminator, is presented in this paper to provide active gated technology. In recent years, we have developed these key components and learned the system parameters, which are most beneficial to nighttime (in all weather conditions) driving in terms of field of view, illumination profile, resolution, and processing power. We shall present our approach of a camera-based advanced driver assistance systems (ADAS) named BrightEye™, which makes use of the AGIS technology in the automotive field.

  8. Reminder systems to improve patient adherence to tuberculosis clinic appointments for diagnosis and treatment

    Science.gov (United States)

    Liu, Qin; Abba, Katharine; Alejandria, Marissa M; Sinclair, David; Balanag, Vincent M; Lansang, Mary Ann D

    2014-01-01

    Background People with active tuberculosis (TB) require six months of treatment. Some people find it difficult to complete treatment, and there are several approaches to help ensure completion. One such system relies on reminders, where the health system prompts patients to attend for appointments on time, or re-engages people who have missed or defaulted on a scheduled appointment. Objectives To assess the effects of reminder systems on improving attendance at TB diagnosis, prophylaxis, and treatment clinic appointments, and their effects on TB treatment outcomes. Search methods We searched the Cochrane Infectious Diseases Group Specialized Register, Cochrane Effective Practice andOrganization of Care Group Specialized Register, CENTRAL,MEDLINE, EMBASE, LILACS, CINAHL, SCI-EXPANDED, SSCI, m RCT, and the Indian Journal of Tuberculosis without language restriction up to 29 August 2014. We also checked reference lists and contacted researchers working in the field. Selection criteria Randomized controlled trials (RCTs), including cluster RCTs and quasi-RCTs, and controlled before-and-after studies comparing reminder systems with no reminders or an alternative reminder system for people with scheduled appointments for TB diagnosis, prophylaxis, or treatment. Data collection and analysis Two review authors independently extracted data and assessed the risk of bias in the included trials. We compared the effects of interventions by using risk ratios (RR) and presented RRs with 95% confidence intervals (CIs). Also we assessed the quality of evidence using the GRADE approach. Main results Nine trials, including 4654 participants, met our inclusion criteria. Five trials evaluated appointment reminders for people on treatment for active TB, two for people on prophylaxis for latent TB, and four for people undergoing TB screening using skin tests.We classified the interventions into 'pre-appointment' reminders (telephone calls or letters prior to a scheduled appointment) or

  9. Sensorimotor gating deficits in multiple system atrophy

    DEFF Research Database (Denmark)

    Zoetmulder, Marielle; Biernat, Heidi Bryde; Nikolic, Miki

    2014-01-01

    Prepulse inhibition (PPI) of the auditory blink reflex is a measure of sensorimotor gating, which reflects an organism's ability to filter out irrelevant sensory information. PPI has never been studied in patients with multiple system atrophy (MSA), although sensorimotor deficits are frequently...

  10. A web-based appointment system to reduce waiting for outpatients: A retrospective study

    Directory of Open Access Journals (Sweden)

    Cao Wenjun

    2011-11-01

    Full Text Available Abstract Background Long waiting times for registration to see a doctor is problematic in China, especially in tertiary hospitals. To address this issue, a web-based appointment system was developed for the Xijing hospital. The aim of this study was to investigate the efficacy of the web-based appointment system in the registration service for outpatients. Methods Data from the web-based appointment system in Xijing hospital from January to December 2010 were collected using a stratified random sampling method, from which participants were randomly selected for a telephone interview asking for detailed information on using the system. Patients who registered through registration windows were randomly selected as a comparison group, and completed a questionnaire on-site. Results A total of 5641 patients using the online booking service were available for data analysis. Of them, 500 were randomly selected, and 369 (73.8% completed a telephone interview. Of the 500 patients using the usual queuing method who were randomly selected for inclusion in the study, responses were obtained from 463, a response rate of 92.6%. Between the two registration methods, there were significant differences in age, degree of satisfaction, and total waiting time (P P > 0.05. Being ignorant of online registration, not trusting the internet, and a lack of ability to use a computer were three main reasons given for not using the web-based appointment system. The overall proportion of non-attendance was 14.4% for those using the web-based appointment system, and the non-attendance rate was significantly different among different hospital departments, day of the week, and time of the day (P Conclusion Compared to the usual queuing method, the web-based appointment system could significantly increase patient's satisfaction with registration and reduce total waiting time effectively. However, further improvements are needed for broad use of the system.

  11. Digital systems from logic gates to processors

    CERN Document Server

    Deschamps, Jean-Pierre; Terés, Lluís

    2017-01-01

    This textbook for a one-semester course in Digital Systems Design describes the basic methods used to develop “traditional” Digital Systems, based on the use of logic gates and flip flops, as well as more advanced techniques that enable the design of very large circuits, based on Hardware Description Languages and Synthesis tools. It was originally designed to accompany a MOOC (Massive Open Online Course) created at the Autonomous University of Barcelona (UAB), currently available on the Coursera platform. Readers will learn what a digital system is and how it can be developed, preparing them for steps toward other technical disciplines, such as Computer Architecture, Robotics, Bionics, Avionics and others. In particular, students will learn to design digital systems of medium complexity, describe digital systems using high level hardware description languages, and understand the operation of computers at their most basic level. All concepts introduced are reinforced by plentiful illustrations, examples, ...

  12. Gate controlled high efficiency ballistic energy conversion system

    NARCIS (Netherlands)

    Xie, Yanbo; Bos, Diederik; de Boer, Hans L.; van den Berg, Albert; Eijkel, Jan C.T.; Zengerle, R.

    2013-01-01

    Last year we demonstrated the microjet ballistic energy conversion system[1]. Here we show that the efficiency of such a system can be further improved by gate control. With gate control the electrical current generation is enhanced a hundred times with respect to the current generated from the zeta

  13. Implementation of a funnel-and-gate trademark remediation system

    International Nuclear Information System (INIS)

    O'Brien, K.; Keyes, G.; Sherman, N.

    1997-01-01

    Funnel-and-gate trademark systems are gaining attention, not necessarily because they speed up the remediation process, but because their use recognizes the limitations of groundwater cleanup programs and factors these limitations into minimizing the lifetime costs of implementing remedial actions. The term funnel-and-gate refers to the installation of low-permeability barriers downgradient of impacted groundwater which are arranged so as to direct the flow of the groundwater through treatment gates. The flow through the treatment gates is driven by natural groundwater gradients, eliminating extraction pumps and above-ground treatment systems. The treatment gates are designed specifically to treat the contamination in the groundwater that will flow through the gates. Funnel-and-gate trademark systems attempt to eliminate or at least minimize mechanical systems, thereby reducing the long-term operation and maintenance costs that so often drive up the lifetime costs of remedial projects. Long-term operation and maintenance costs are reduced because the site does not need a continuous input of energy or manpower. In addition, groundwater monitoring and system compliance issues can be streamlined for even greater cost savings. Since it is a developing technology, there are few commercial applications where funnel-and-gate trademark systems have been proven. Concurrent with groundwater investigations, a number of remedial actions had been undertaken at a property in California. Underground storage tanks which contain diesel fuels were excavated and removed. A former dry well suspected of being the source of chlorinated-solvent impacts was also excavated

  14. Statistical Determination of the Gating Windows for Respiratory-Gated Radiotherapy Using a Visible Guiding System.

    Science.gov (United States)

    Oh, Se An; Yea, Ji Woon; Kim, Sung Kyu

    2016-01-01

    Respiratory-gated radiation therapy (RGRT) is used to minimize the radiation dose to normal tissue in lung-cancer patients. Although determining the gating window in the respiratory phase of patients is important in RGRT, it is not easy. Our aim was to determine the optimal gating window when using a visible guiding system for RGRT. Between April and October 2014, the breathing signals of 23 lung-cancer patients were recorded with a real-time position management (RPM) respiratory gating system (Varian, USA). We performed statistical analysis with breathing signals to find the optimal gating window for guided breathing in RGRT. When we compared breathing signals before and after the breathing training, 19 of the 23 patients showed statistically significant differences (p guiding system. RGRT was performed with the RPM system to confirm the usefulness of the visible guiding system. The RPM system and our visible guiding system improve the respiratory regularity, which in turn should improve the accuracy and efficiency of RGRT.

  15. Implementation of a funnel-and-gate remediation system

    International Nuclear Information System (INIS)

    O'Brien, K.; Keyes, G.; Sherman, N.

    1997-01-01

    A funnel-and-gate trademark system incorporating activated carbon was deemed the most attractive remediation method for an active lumber mill in the western United States. Petroleum hydrocarbons, chlorinated solvents, pentachlorophenol, and tetrachlorophenol were detected in on-site groundwater samples. The shallow aquifer consists of a heterogeneous mixture of marine deposits and artificial fill, underlain by low-permeability siltstones and mudstone. In the funnel-and-gate trademark system, a low-permeability cutoff wall was installed to funnel groundwater flow to a smaller area (a open-quotes gateclose quotes) where a passive below-grade treatment system treats the plume as it flows through the gate. Groundwater flow modeling focused on the inhomogeneities of the aquifer and the spatial relationship between gate(s) and barrier walls. The gate design incorporates several factors, including contaminant concentration, flow rate, and time between carbon changeouts. To minimize back pressure and maximize residence time, each gate was designed using 1.25-meter (4-foot) diameter corrugated metal pipe filled with a 1.25-meter (4-foot) thick bed of activated carbon. The configuration will allow water to flow through the treatment gates without pumps. The installed system is 190 meters (625 feet) long and treats approximately 76 L/min (20 gpm) during the winter months

  16. A System For High Flexibility Entangling Gates With Trapped Ions

    Science.gov (United States)

    Milne, Alistair; Edmunds, Claire; Mavadia, Sandeep; Green, Todd; Biercuk, Michael

    Trapped ion qubits may be entangled via coupling to shared modes of motion using spin-dependent forces generated by optical fields. Residual qubit-motional coupling at the conclusion of the entangling operation is the dominant source of infidelity in this type of gate. For synchronously entangling increasing numbers of ions, longer gate times are required to minimise this residual coupling. We present a scheme that enables the state of each qubit to be simultaneously decoupled from all motional modes in an arbitrarily chosen gate time, increasing the gate fidelity and scalability. This is achieved by implementing discrete phase shifts in the optical field moderating the entangling operation. We describe an experimental system based on trapped ytterbium ions and demonstrate this scheme for two-qubit entangling gates on ytterbium ion pairs.

  17. Appointment reminder systems are effective but not optimal: results of a systematic review and evidence synthesis employing realist principles

    Directory of Open Access Journals (Sweden)

    McLean SM

    2016-04-01

    Full Text Available Sionnadh Mairi McLean,1 Andrew Booth,2 Melanie Gee,3 Sarah Salway,2 Mark Cobb,4 Sadiq Bhanbhro,3 Susan A Nancarrow5 1Faculty of Health and Wellbeing, Sheffield Hallam University, Sheffield, UK; 2School of Health and Related Research, University of Sheffield, Sheffield, UK; 3Centre for Health and Social Care Research, Sheffield Hallam University, Sheffield, UK; 4Therapeutics & Palliative Care, Sheffield Teaching Hospitals, Sheffield, UK; 5School of Health and Human Science, Southern Cross University, East Lismore, NSW, Australia Abstract: Missed appointments are an avoidable cost and resource inefficiency which impact upon the health of the patient and treatment outcomes. Health care services are increasingly utilizing reminder systems to manage these negative effects. This study explores the effectiveness of reminder systems for promoting attendance, cancellations, and rescheduling of appointments across all health care settings and for particular patient groups and the contextual factors which indicate that reminders are being employed sub-optimally. We used three inter-related reviews of quantitative and qualitative evidence. Firstly, using pre-existing models and theories, we developed a conceptual framework to inform our understanding of the contexts and mechanisms which influence reminder effectiveness. Secondly, we performed a review following Centre for Reviews and Dissemination guidelines to investigate the effectiveness of different methods of reminding patients to attend health service appointments. Finally, to supplement the effectiveness information, we completed a review informed by realist principles to identify factors likely to influence non-attendance behaviors and the effectiveness of reminders. We found consistent evidence that all types of reminder systems are effective at improving appointment attendance across a range of health care settings and patient populations. Reminder systems may also increase cancellation and

  18. Fake passports and appointed communities: Nation and transnationalism in the Danish asylum system

    DEFF Research Database (Denmark)

    Whyte, Zachary

    2003-01-01

    Nationality underwrites a great deal of the Danish asylum process, and of the refugee regime as a whole. The housing and care of asylum seekers, handled by the Danish Red Cross, is based on classifications by nationality. Bending a phrase from Benedict Anderson, these might be called "appointed...... communities". While the Danish asylum system in principle performs individual determination procedures for asylum seekers, granting refugee status on a case-by-case basis, in practice those identified as Iraqi or Afghani have had a very high acceptance rate. However, it is clearly the case that not all asylum...... seekers have citizenship of the countries they claim to come from, or indeed feel they come from the countries of which they have citizenship. In this context, we must enquire about the mechanics of determining nationality and about how asylum seekers themselves relate to national identities. I argue...

  19. Reduced energy consumption by using streamlined gating systems

    Directory of Open Access Journals (Sweden)

    Niels Skat Tiedje

    2008-11-01

    Full Text Available In foundries a lot of effort is done to minimize energy consumption in the production to reduce costs and hence increase the competitiveness. At the same time the foundries must live up to the increased demands for high quality castings.Traditional gating systems are known for a straight tapered down runner, a well base and 90?bends in the runner system. Previous work has shown that the traditional way of designing gating systems creates high inconsistency in fl ow patterns during fi lling. In the streamlined gating systems there are no sharp changes in direction and a large effort is done to confi ne and control the fl ow of the molten metal during mould fi lling.The main objective in the work presented here is to use the principles of the streamlined gating systems to reduce the weight of the gating system relative to the traditional layouts. By reducing the weight of gating system and thereby improving yield, the amount of molten iron needed is also reduced, hence reducing the energy consumption for melting.Experiments in real production lines have proven that it is possible to achieve a reduction in the poured weight by using the streamlined gating systems. In a layout for casting of three valve housings in a vertically parted mould the weight of the gating system was reduced by 1.1 kg changing from the traditional layouts to the streamlined gating systems. This weight reduction corresponds in this case to a 20% weight reduction for the gating system.Using streamlined gating systems with fan gates to give a benefi cial heat distribution in the castings may be an effi cient tool to eliminate the need for heat treatment. In the experiments the change in gating system from the traditional layout to the streamlined layout removed the need for heat treatment. This obviously means a huge energy saving in the foundry. The energy consumption for heat treatment of iron has been found to be 0.489 kWh/kg. The valve housing in the experiments weighs 3

  20. SU-E-T-350: Verification of Gating Performance of a New Elekta Gating Solution: Response Kit and Catalyst System

    International Nuclear Information System (INIS)

    Xie, X; Cao, D; Housley, D; Mehta, V; Shepard, D

    2014-01-01

    Purpose: In this work, we have tested the performance of new respiratory gating solutions for Elekta linacs. These solutions include the Response gating and the C-RAD Catalyst surface mapping system.Verification measurements have been performed for a series of clinical cases. We also examined the beam on latency of the system and its impact on delivery efficiency. Methods: To verify the benefits of tighter gating windows, a Quasar Respiratory Motion Platform was used. Its vertical-motion plate acted as a respiration surrogate and was tracked by the Catalyst system to generate gating signals. A MatriXX ion-chamber array was mounted on its longitudinal-moving platform. Clinical plans are delivered to a stationary and moving Matrix array at 100%, 50% and 30% gating windows and gamma scores were calculated comparing moving delivery results to the stationary result. It is important to note that as one moves to tighter gating windows, the delivery efficiency will be impacted by the linac's beam-on latency. Using a specialized software package, we generated beam-on signals of lengths of 1000ms, 600ms, 450ms, 400ms, 350ms and 300ms. As the gating windows get tighter, one can expect to reach a point where the dose rate will fall to nearly zero, indicating that the gating window is close to beam-on latency. A clinically useful gating window needs to be significantly longer than the latency for the linac. Results: As expected, the use of tighter gating windows improved delivery accuracy. However, a lower limit of the gating window, largely defined by linac beam-on latency, exists at around 300ms. Conclusion: The Response gating kit, combined with the C-RAD Catalyst, provides an effective solution for respiratorygated treatment delivery. Careful patient selection, gating window design, even visual/audio coaching may be necessary to ensure both delivery quality and efficiency. This research project is funded by Elekta

  1. Speed control system for an access gate

    Science.gov (United States)

    Bzorgi, Fariborz M [Knoxville, TN

    2012-03-20

    An access control apparatus for an access gate. The access gate typically has a rotator that is configured to rotate around a rotator axis at a first variable speed in a forward direction. The access control apparatus may include a transmission that typically has an input element that is operatively connected to the rotator. The input element is generally configured to rotate at an input speed that is proportional to the first variable speed. The transmission typically also has an output element that has an output speed that is higher than the input speed. The input element and the output element may rotate around a common transmission axis. A retardation mechanism may be employed. The retardation mechanism is typically configured to rotate around a retardation mechanism axis. Generally the retardation mechanism is operatively connected to the output element of the transmission and is configured to retard motion of the access gate in the forward direction when the first variable speed is above a control-limit speed. In many embodiments the transmission axis and the retardation mechanism axis are substantially co-axial. Some embodiments include a freewheel/catch mechanism that has an input connection that is operatively connected to the rotator. The input connection may be configured to engage an output connection when the rotator is rotated at the first variable speed in a forward direction and configured for substantially unrestricted rotation when the rotator is rotated in a reverse direction opposite the forward direction. The input element of the transmission is typically operatively connected to the output connection of the freewheel/catch mechanism.

  2. Terminal appointment system design by non-stationary M(t)/E /c(t) queueing model and genetic algorithm

    DEFF Research Database (Denmark)

    Chen, G.; Govindan, Kannan; Yang, Z.-Z.

    2013-01-01

    Long truck queue is a common problem at big marine container terminals, where the resources and equipment are usually scheduled to serve ships prior to trucks. To reduce truck queues, some container terminals adopt terminal appointment system (TAS) to manage truck arrivals. This paper addresses t...

  3. The East Garrington Trench and Gate system: it works

    International Nuclear Information System (INIS)

    Bowles, M.; Rimbey, S.; Bentley, L.; Thomas, D.; Hoyne, B.

    1997-01-01

    A 'trench and gate' system (a modification of the 'funnel and gate' system) has been installed at the Amoco-operated East Garrington gas plant in Alberta to provide long-term remediation for treating contaminated groundwater plumes hosted by low hydraulic conductivity sediments. Modification to the funnel and gate design includes an up gradient high hydraulic conductivity trench and a down gradient infiltration gallery which was found to be effective in biodegrading BTEX (benzene, toluene, ethylbenzene and xylene) compounds. A comprehensive monitoring program was set up to characterize the groundwater flow system. Several indigenous hydrocarbon degrading organisms have been identified. It was shown that locally, under aerobic conditions, phosphorus was the limiting nutrient. 13 refs., 3 tabs., 10 figs

  4. Introduction to embedded system design using field programmable gate arrays

    CERN Document Server

    Dubey, Rahul

    2009-01-01

    Offers information on the use of field programmable gate arrays (FPGAs) in the design of embedded systems. This text considers a hypothetical robot controller as an embedded application and weaves around it related concepts of FPGA-based digital design. It is suitable for both students and designers who have worked with microprocessors.

  5. Investigation of the stability of melt flow in gating systems

    DEFF Research Database (Denmark)

    Tiedje, Niels Skat; Larsen, Per

    2011-01-01

    Melt flow in four different gating systems designed for production of brake discs was analysed experimentally and by numerical modelling. In the experiments moulds were fitted with glass fronts and melt flow was recorded on video. The video recordings were compared with modelling of melt flow in ...

  6. Speed limits for quantum gates in multiqubit systems

    NARCIS (Netherlands)

    Ashhab, S.; De Groot, P.C.; Nori, F.

    2012-01-01

    We use analytical and numerical calculations to obtain speed limits for various unitary quantum operations in multiqubit systems under typical experimental conditions. The operations that we consider include single-, two-, and three-qubit gates, as well as quantum-state transfer in a chain of

  7. Patients' willingness to utilize a SMS-based appointment scheduling system at a family practice unit in a developing country.

    Science.gov (United States)

    Adedokun, Ayoade; Idris, Oladipo; Odujoko, Tolulope

    2016-03-01

    Aim The investigators aimed to assess the willingness of patients to utilize and pay for a proposed short message service- (SMS) based appointment scheduling service. Telecommunication applications have been introduced to improve the delivery of healthcare services in developed countries; however, public-funded healthcare systems in developing countries like Nigeria are mostly unfamiliar with the use of such technologies for improving healthcare access. We proposed a SMS-based (text message) appointment scheduling system to consenting subjects at an outpatients' clinic and explored their willingness to utilize and pay for the service. Using semi-structured interview schedules, we collected information on: estimated arrival time, most important worry when seeking for healthcare services at public hospitals in the study setting, ownership of a mobile phone, willingness to utilize a SMS-based appointment for clinic visits and willingness to pay for the service. In addition, respondents were asked to suggest a tariff for the proposed system. Findings A total of 500 consecutively recruited patients aged 16-86 (42.1±15.4) years participated; 54% (n=270) were females. Waiting time ranged from 1-7.5 h (3.9±1.1). Two overlapping themes emerged as most important worries: crowded waiting rooms and long waiting time. Ownership of mobile phones was reported by 96.4% (n=482) of subjects. Nearly all favoured the proposed appointment scheduling system (n=486, 97.2%). Majority of patients who favoured the system were willing to pay for the service (n=484, 99.6%). Suggested tariff ranged from 0.03 to 20.83 (1.53±2.11) US dollars; 89.8% (n=349) of the subjects suggested tariffs that were greater than the prevailing retail cost of the proposed service. In sum, our findings indicate that patients in this study were willing to utilize and pay for a proposed SMS-based appointment scheduling system. The findings have implications for policies aimed at improving healthcare access and

  8. Gating system design for the space device case using T-Flex CAD

    Directory of Open Access Journals (Sweden)

    Ayusheev Munkhe-Zul

    2017-01-01

    Full Text Available The judicious selection of gating system for the consumable pattern takes a lot of time, labour and other significant resources. The modern design technologies provide quick and effective ways for gating system calculation and casting process simulation. Gating system modeling allows estimating different kinds of defects which can occur at the developing stage of casting process. Moreover, it is possible to modify the whole gating system configuration if some parameters are changed. Analyzing these data and modifying the gating system characteristics high quality of castings can be achieved.

  9. Detection performance of laser range-gated imaging system

    Science.gov (United States)

    Xu, Jun; Li, Xiaofeng; Luo, Jijun; Zhang, Shengxiu; Xu, Yibin

    2010-10-01

    Laser radar is rapidly developing towards very capable sensors for number of applications such as military sensing and guidance, auto collision avoidance, robotic vision and atmospheric sensing. In this paper, the detection performance of non-scanned Laser Rang-gated (LRG) imaging system is studied. In order to compute the detection range of laser active imaging system, the range equation is derived by using laser illuminating model and considering factors which affect system imaging quality. According to the principle of laser radar and the characters of objects and the detectors in special applied setting, it mainly deduced the non-scanned laser radar range equation of the range-gated system, meanwhile, the SNR model of non-scanned LRG imaging system is set up. Then, relationship of the detection probability, the false alarm probability and the signal-to-noise ratio in the non-scanned LRG imaging system are analyzed, the influence factors of system's performance are pointed out, and the solution is proposed. The detection performance simulation software of non-scanned LRG imaging system is designed with MATLAB and the performance of the imaging system is simulated.

  10. [The Appointment of Paediatric Professorships in the Soviet Occupation Zone and the early GDR. The Impact of the Political System Change after 1945].

    Science.gov (United States)

    Hinz-Wessels, Annette

    2016-01-01

    This paper examines the impact of the political system change after 1945 on the appointment of paediatric professorships in the Soviet Occupation Zone and the GDR up until the time the Wall was built in 1961. It can be demonstrated that the political purge in the post-war period had only minor impact on the appointment of professorships and the National Socialist past no longer mattered after the conclusion of denazification. In 1957, the proportion of former NSDAP members among East German university professors of paediatrics was 100 per cent. When it came to new appointments, both members of the "bourgeois" academic non-professorial teaching staff from the GDR as well as paediatricians from West Germany, who had largely gained their scientifically qualifications under National Socialism, were in the running. A politically-controlled elite exchange did not take place until the construction of the Wall. State and party organs generally followed the personnel proposals of the universities since an insufficient number of qualified candidates was available for the systematic appointment of ,,progressive" paediatricians. Given the lack of staff, the SED personnel policy was aimed at the integration of previous elites, as long as they behaved loyally towards the new state. Since the East German faculties continued to make the questioning of the professionally competent professors in West Germany and East Germany the basis for their appointment lists, West German university paediatricians were able to exert considerable influence on the appointment of East German paediatric professorship until 1960s.

  11. Assessing the relationship between technology readiness and continuance intention in an E-appointment system: relationship quality as a mediator.

    Science.gov (United States)

    Chen, Shih-Chih; Jong, Din; Lai, Min-Tsai

    2014-09-01

    Numerous types of self-service technologies have prevailed due to innovations in network and information technology. To hospitals, patient intentions to continue to use the e-appointment system are crucial. Previous investigations discussed only the relationships between the technology readiness of users and their continuance intentions, and ignored the most important mediator, relationship quality. This study explored the relationships among technology readiness, relationship quality, and continuance intention. The research results demonstrated that both optimism and innovativeness significantly and positively influenced continuance intention through the mediating effect of relationship quality. However, discomfort and insecurity hid not significantly influence relationship quality or continuance intention. Finally, theoretical contributions, managerial implications and future research directions were discussed.

  12. Usefulness of a new online patient-specific quality assurance system for respiratory-gated radiotherapy.

    Science.gov (United States)

    Kurosawa, Tomoyuki; Tachibana, Hidenobu; Moriya, Shunsuke; Miyakawa, Shin; Nishio, Teiji; Sato, Masanori

    2017-11-01

    The accuracy of gated irradiation may decrease when treatment is performed with short "beam-on" times. Also, the dose is subject to variation between treatment sessions if the respiratory rate is irregular. We therefore evaluated the impact of the differences between gated and non-gated treatment on doses using a new online quality assurance (QA) system for respiratory-gated radiotherapy. We generated dose estimation models to associate dose and pulse information using a 0.6 cc Farmer chamber and our QA system. During gated irradiation with each of seven regular and irregular respiratory patterns, with the Farmer chamber readings as references, we evaluated our QA system's accuracy. We then used the QA system to assess the impact of respiratory patterns on dose distribution for three lung and three liver radiotherapy plans. Gated and non-gated plans were generated and compared. There was agreement within 1.7% between the ionization chamber and our system for several regular and irregular motion patterns. For dose distributions with measured errors, there were larger differences between gated and non-gated treatment for high-dose regions within the planned treatment volume (PTV). Compared with a non-gated plan, PTV D 95% for a gated plan decreased by -1.5% to -2.6%. Doses to organs at risk were similar with both plans. Our simple system estimated the radiation dose to the patient using only pulse information from the linac, even during irregular respiration. The quality of gated irradiation for each patient can be verified fraction by fraction. Copyright © 2017 Associazione Italiana di Fisica Medica. Published by Elsevier Ltd. All rights reserved.

  13. A multiple time-gated system for pulsed digital gamma-ray spectroscopy

    International Nuclear Information System (INIS)

    Tan, H.; Fallu-Labruyere, A.; Hennig, W.; Chu, Y.X.; Warburton, W.K.; Mitra, S.; Wielopolski, L.

    2008-01-01

    Neutron activation analysis (NAA) systems that use pulsed neutron generators (NGs) employ spectrum gating procedures to segregate nuclear processes by acquiring gamma-ray spectra separately when the generator is on (HIGH gate) and off (LOW gate). Often, the actual neutron burst lags the leading edge of the HIGH gate signal by a few μs. Thus, count rates vary not only between the on and off states of the NG, but within them as well. Recent advances in digital gamma-ray spectrometers that allowed the concurrent acquisition of data by sorting events into two separate spectra based on gate status suggested that a time-resolved analysis that further subdivided the neutron pulse cycle could obtain further information to separate gamma-rays produced by different nuclear reactions. In this paper we introduce a gating system for time-resolved NAA that is capable of concurrently acquiring as many as 16 spectra from up to 8 user-defined time intervals during each of the HIGH gate and LOW gate periods, each with all required timing and count rate information. We present the new gating system's implementation, operation and some first experimental test results. (author)

  14. Gated integrator PXI-DAQ system for Thomson scattering diagnostics

    Energy Technology Data Exchange (ETDEWEB)

    Patel, Kiran, E-mail: kkpatel@ipr.res.in; Pillai, Vishal; Singh, Neha; Thomas, Jinto; Kumar, Ajai

    2017-06-15

    Gated Integrator (GI) PXI based data acquisition (DAQ) system has been designed and developed for the ease of acquiring fast Thomson Scattered signals (∼50 ns pulse width). The DAQ system consists of in-house designed and developed GI modules and PXI-1405 chassis with several PXI-DAQ modules. The performance of the developed system has been validated during the SST-1 campaigns. The dynamic range of the GI module depends on the integrating capacitor (C{sub i}) and the modules have been calibrated using 12 pF and 27 pF integrating capacitors. The developed GI module based data acquisition system consists of sixty four channels for simultaneous sampling using eight PXI based digitization modules having eight channels per module. The error estimation and functional tests of this unit are carried out using standard source and also with the fast detectors used for Thomson scattering diagnostics. User friendly Graphical User Interface (GUI) has been developed using LabVIEW on Windows platform to control and acquire the Thomson scattering signal. A robust, easy to operate and maintain with low power consumption, having higher dynamic range with very good sensitivity and cost effective DAQ system is developed and tested for the SST-1 Thomson scattering diagnostics.

  15. Gating System Design for Casting thin Aluminium Alloy (Al-Si Plates

    Directory of Open Access Journals (Sweden)

    Victor ANJO

    2013-11-01

    Full Text Available The main problems caused by improper gating are entrained aluminium oxide films, cuts and washes, low casting yield and entrapped gas. This study describes the design of a gating system to produce thin Aluminium cast alloy plates of different sizes and thicknesses of 4mm, 6mm, 8mm, and 10mm using the non-pressurized gating with ratio of 1:4:4 and green sand moulding technique. The gating design was based on the laws of fluid mechanics and empirical rules of gating for non ferrous metals. The equipments used for this experiment includes; a coal fired crucible furnace and an X-Ray machine. Materials used include; silica sand, clay, wood, glue and Aluminium alloy scraps. The experimental procedure involved: the gating design calculations, construction of wooden pattern and gating; using the wooden pattern and gating to produce the mould cavities and gating; melting, melt treatment and pouring of melt in the sand mould to produce the casting. The plate castings after removal from mould were visually examined for surface defects and after fettling and cleaning X-Ray radiography was used to find the internal soundness of the castings. From the results obtained in the experiment, it was found that there were no internal defects and quality castings were produced.

  16. Accuracy Verification of Respiratory-gated Radiotherapy that Combines the Respiration-Monitoring Device and Respiratory-gated System.

    Science.gov (United States)

    Shintani, Naoya; Monzen, Hajime; Tamura, Masaya; Asai, Yoshiyuki; Shimomura, Kouhei; Matsumoto, Kenji; Okumura, Masahiko; Nishimura, Yasumasa

    2016-01-01

    The purpose of this study is to evaluate the mechanical accuracy of a respiratory-gated radiation system that combines the Linear Indicator-equipped Abches respiration-monitoring device and the Varian Real-time Position Management system (LI-RPM system). This combined configuration, implemented for the first time in Japan, was compared with the stand-alone Varian RPM system (RPM system). The delay times, dose profiles, and output waveforms of the LI-RPM and RPM systems were evaluated using a self-produced dynamic phantom. The delay times for the LI-RPM and RPM systems were both 0.1 s for 4 s and 8 s test periods. The corresponding output waveform correlation factors (R 2 ) for the 4 s and 8 s test periods were 0.9981 and 0.9975, respectively. No difference was observed in the dose profiles of the two systems. Thus, the present results indicate that the proposed LI-RPM combined respiratory-gated radiation system has similar properties to the RPM system. However, it offers several advantages in terms of its versatility, including its alignment assistance capabilities for non-coplanar treatments.

  17. Questionnaire survey about use of an online appointment booking system in one large tertiary public hospital outpatient service center in China.

    Science.gov (United States)

    Zhang, MinMin; Zhang, CongXin; Sun, QinWen; Cai, QuanCai; Yang, Hua; Zhang, YinJuan

    2014-06-09

    As a part of nationwide healthcare reforms, the Chinese government launched web-based appointment systems (WAS) to provide a solution to problems around outpatient appointments and services. These have been in place in all Chinese public tertiary hospitals since 2009. Questionnaires were collected from both patients and doctors in one large tertiary public hospital in Shanghai, China.Data were analyzed to measure their satisfaction and views about the WAS. The 1000 outpatients randomly selected for the survey were least satisfied about the waiting time to see a doctor. Even though the WAS provided a much more convenient booking method, only 17% of patients used it. Of the 197 doctors surveyed, over 90% thought it was necessary to provide alternative forms of appointment booking systems for outpatients. However, about 80% of those doctors who were not associated professors would like to provide an 'on-the-spot' appointment option, which would lead to longer waits for patients. Patients were least satisfied about the waiting times. To effectively reduce appointment-waiting times is therefore an urgent issue. Despite the benefits of using the WAS, most patients still registered via the usual method of queuing, suggesting that hospitals and health service providers should promote and encourage the use of the WAS. Furthermore, Chinese health providers need to help doctors to take others' opinions or feedback into consideration when treating patients to minimize the gap between patients' and doctors' opinions. These findings may provide useful information for both practitioners and regulators, and improve recognition of this efficient and useful booking system, which may have far-reaching and positive implications for China's ongoing reforms.

  18. Experimental analysis of flow of ductile cast iron in stream lined gating systems

    DEFF Research Database (Denmark)

    Skov-Hansen, Søren; Green, Nick; Tiedje, Niels Skat

    2008-01-01

    Streamlined gating systems have been developed for production of high integrity ductile cast iron parts. Flow of ductile cast iron in streamlined gating systems was studied in glass fronted sand moulds where flow in the gating system and casting was recorded by a digital video camera. These results...... are compared with real time x-ray recordings of melt flow. Results show that flow patterns are the same using both techniques. The glass fronted moulds give global information on flow in the whole gating system and casting while the x-ray analysis gives detailed information on specific areas. The experiments...... show how the quality of pouring, design of ingates, design of bends and flow over cores influence melt flow and act to determine the quality of the castings....

  19. In situ ground water remediation using the trench and gate system

    Energy Technology Data Exchange (ETDEWEB)

    Bowles, M.W.; Bentley, L.R.; Hoyne, B.; Thomas, D.A.

    2000-04-01

    The trench and gate remediation system is a funnel and gate design modified for installation in tills and other low permeability sediments. Modifications include the addition of high hydraulic conductivity trenches along the upgradient side of the funnel walls and a discharge reinfiltration gallery downgradient from the treatment gate. Preferential ground water flow through the high permeability trenches and reinfiltration gallery prevents mounding, which otherwise forces flow beneath and around funnel walls. The resultant capture zone is larger, both horizontally and vertically, than the cross-sectional funnel area and is significantly larger than the capture zone of a similar funnel and gate system. The system constitutes and economical, in situ, long-term contaminant plume capture and treatment method. In effectiveness and cost, the trench and gate system compares favorably with, or outperforms, other remediation systems in near-surface, low permeability dissolved contaminant scenarios. A prototype trench and gate system was installed at the East Garrington Gas Plant, Alberta, Canada, in 1995. The installation demonstrated the effectiveness of the concept, and the system has successfully prevented off-site migration of dissolved hydrocarbon contaminants.

  20. Gating Systems for Sizeable Castings from Al Alloys Cast into Ceramic Moulds

    OpenAIRE

    Stachovec I.; Horáček M.; Zemčík L.; Kolda V.; Horenský J.

    2012-01-01

    In contrast to casting to conventional non-reusable “sand” moulds, for which calculating technique for an optimum design of the gating system is comparatively well-developed, a trial-and-error method is applied mostly for casting to ceramic shell moulds made by the investment casting technology. A technologist selects from gating systems of several types (that are standardized by the foundry mostly) on the basis of experience. However, this approach is not sustainable with ever growing demand...

  1. Teachers' Attitudes toward the Appointment of Women as School Leaders: The Case of the Arab Education System in Israel

    Science.gov (United States)

    Arar, Khalid; Abramovitz, Ruth

    2013-01-01

    The trend towards gender equality in principalship appointments continues to interest researchers, especially when it appears in traditional societies that maintain patriarchal, anti-feminist attitudes and values. Arab society in Israel is undergoing transition from traditionalism to modernism. Arab women hold the majority of Arab school teaching…

  2. Influence of range-gated intensifiers on underwater imaging system SNR

    Science.gov (United States)

    Wang, Xia; Hu, Ling; Zhi, Qiang; Chen, Zhen-yue; Jin, Wei-qi

    2013-08-01

    Range-gated technology has been a hot research field in recent years due to its high effective back scattering eliminating. As a result, it can enhance the contrast between a target and its background and extent the working distance of the imaging system. The underwater imaging system is required to have the ability to image in low light level conditions, as well as the ability to eliminate the back scattering effect, which means that the receiver has to be high-speed external trigger function, high resolution, high sensitivity, low noise, higher gain dynamic range. When it comes to an intensifier, the noise characteristics directly restrict the observation effect and range of the imaging system. The background noise may decrease the image contrast and sharpness, even covering the signal making it impossible to recognize the target. So it is quite important to investigate the noise characteristics of intensifiers. SNR is an important parameter reflecting the noise features of a system. Through the use of underwater laser range-gated imaging prediction model, and according to the linear SNR system theory, the gated imaging noise performance of the present market adopted super second generation and generation Ⅲ intensifiers were theoretically analyzed. Based on the active laser underwater range-gated imaging model, the effect to the system by gated intensifiers and the relationship between the system SNR and MTF were studied. Through theoretical and simulation analysis to the image intensifier background noise and SNR, the different influence on system SNR by super second generation and generation Ⅲ ICCD was obtained. Range-gated system SNR formula was put forward, and compared the different effect influence on the system by using two kind of ICCDs was compared. According to the matlab simulation, a detailed analysis was carried out theoretically. All the work in this paper lays a theoretical foundation to further eliminating back scattering effect, improving

  3. Eye tracking and gating system for proton therapy of orbital tumors

    International Nuclear Information System (INIS)

    Shin, Dongho; Yoo, Seung Hoon; Moon, Sung Ho; Yoon, Myonggeun; Lee, Se Byeong; Park, Sung Yong

    2012-01-01

    Purpose: A new motion-based gated proton therapy for the treatment of orbital tumors using real-time eye-tracking system was designed and evaluated. Methods: We developed our system by image-pattern matching, using a normalized cross-correlation technique with LabVIEW 8.6 and Vision Assistant 8.6 (National Instruments, Austin, TX). To measure the pixel spacing of an image consistently, four different calibration modes such as the point-detection, the edge-detection, the line-measurement, and the manual measurement mode were suggested and used. After these methods were applied to proton therapy, gating was performed, and radiation dose distributions were evaluated. Results: Moving phantom verification measurements resulted in errors of less than 0.1 mm for given ranges of translation. Dosimetric evaluation of the beam-gating system versus nongated treatment delivery with a moving phantom shows that while there was only 0.83 mm growth in lateral penumbra for gated radiotherapy, there was 4.95 mm growth in lateral penumbra in case of nongated exposure. The analysis from clinical results suggests that the average of eye movements depends distinctively on each patient by showing 0.44 mm, 0.45 mm, and 0.86 mm for three patients, respectively. Conclusions: The developed automatic eye-tracking based beam-gating system enabled us to perform high-precision proton radiotherapy of orbital tumors.

  4. The Application of The Double Queue Asymmetric Gated Service Polling Control Theory in Intelligent Traffic System

    Directory of Open Access Journals (Sweden)

    Zhao Yi Fan

    2016-01-01

    Full Text Available paper presents a new use of double queues asymmetric gated service polling system in the intelligent traffic light control system.Usually there are more vehicles in main road than minor road,so there are more green light time be needed in the main road.From the computer simulation and theory analysis,we can find that the application of double queues asymmetric gated service polling theory in intelligent traffic system can balance intersections load and set suitable passing time for vehicles to assure the roads open.

  5. Gating Systems for Sizeable Castings from Al Alloys Cast into Ceramic Moulds

    Directory of Open Access Journals (Sweden)

    I. Stachovec

    2012-04-01

    Full Text Available In contrast to casting to conventional non-reusable “sand” moulds, for which calculating technique for an optimum design of the gating system is comparatively well-developed, a trial-and-error method is applied mostly for casting to ceramic shell moulds made by the investment casting technology. A technologist selects from gating systems of several types (that are standardized by the foundry mostly on the basis of experience. However, this approach is not sustainable with ever growing demands on quality of castings and also the economy of their fabrication as well as with new types of complex sizeable castings introduced to the production gradually (by new customers from the aircraft industry above all any more. The simulation software may be used as a possible tool for making the process of optimising gating systems more effective.

  6. ICTP appoints new director

    Science.gov (United States)

    Dacey, James

    2009-11-01

    Fernando Quevedo of the University of Cambridge in the UK has been appointed as the new director of the Abdus Salam International Centre for Theoretical Physics (ICTP) in Trieste, Italy. Quevedo will officially begin his new role this month and replaces Katepalli Sreenivasan, the India-born physicist who has led the institute since 2003.

  7. Evaluation of irradiation position in respiratory-gated radiotherapy using a phantom system simulating patient respiration

    International Nuclear Information System (INIS)

    Oyama, Masaya; Ueda, Takashi; Kitoh, Satoshi; Tanaka, Takashi; Goka, Tomonori; Ogino, Takashi

    2006-01-01

    Respiratory-gated (RG) radiotherapy is useful for minimizing the irradiated volume of normal tissues resulting from the shifting of internal structures caused by respiratory movement. The present study was conducted to evaluate the treatment field in RG radiotherapy using a phantom system simulating patient respiration. A phantom system consisting of a 3-cm ball-shaped dummy tumor and film placed in a cork lung phantom was used (THK Co., Ltd.). RG radiotherapy was employed in the expiratory phase. The phantom movement distance was set to 2 cm, and the gating signals from a respiratory-gating system (AZ-733V, Anzai Medical) were varied. The settings used for irradiation were an X-ray energy of 6 MV (PRIMUS, Toshiba Medical Systems), treatment field of 5 cm x 7 cm, and X-ray dose of 100 MU. Images were acquired using an electric portal-imaging device (EPID, OPTIVUE 500), and the X-ray dose distribution was measured by the film method. In images acquired using the EPID, the tumor margins became less clear when the gating signals were increased, and the ITVs were determined to be 3.6 cm, 3.7 cm, 4.2 cm, and 5.1 cm at gating rates of 10%, 25%, 50%, and no gate, respectively. With regard to the X-ray dose distribution measured by the film method, the dose profile in the cephalocaudal direction was shifted toward the expiratory phase, and the degree of shift became greater when the gating signals were increased. In addition, the optimal treatment fields in the cephalocaudal direction were determined to be 5.2 cm, 5.2 cm, 5.6 cm, and 7.0 cm at gating rates of 10%, 25%, 50%, and no gating, respectively. Although RG radiotherapy is useful for improving the accuracy of radiotherapy, the characteristics of the RG radiotherapy technique and the radiotherapy system must be clearly understood when this method is to be employed in clinical practice. Image-guided radiotherapy (IGRT) is now assuming a central role in radiotherapy, and properly identifying internal margins is an

  8. Universal quantum gates for photon-atom hybrid systems assisted by bad cavities

    Science.gov (United States)

    Wang, Guan-Yu; Liu, Qian; Wei, Hai-Rui; Li, Tao; Ai, Qing; Deng, Fu-Guo

    2016-01-01

    We present two deterministic schemes for constructing a CNOT gate and a Toffoli gate on photon-atom and photon-atom-atom hybrid quantum systems assisted by bad cavities, respectively. They are achieved by cavity-assisted photon scattering and work in the intermediate coupling region with bad cavities, which relaxes the difficulty of their implementation in experiment. Also, bad cavities are feasible for fast quantum operations and reading out information. Compared with previous works, our schemes do not need any auxiliary qubits and measurements. Moreover, the schematic setups for these gates are simple, especially that for our Toffoli gate as only a quarter wave packet is used to interact the photon with each of the atoms every time. These atom-cavity systems can be used as the quantum nodes in long-distance quantum communication as their relatively long coherence time is suitable for multi-time operations between the photon and the system. Our calculations show that the average fidelities and efficiencies of our two universal hybrid quantum gates are high with current experimental technology. PMID:27067992

  9. Calculation of the contrast of the calcification in digital mammography system: Gate validation

    Directory of Open Access Journals (Sweden)

    Dooman Arefan

    2018-01-01

    Discussion: According to the SEM rate reported in this research for calculating the contrast of the aluminum foils in the mammography system based on simulation and practical methods, the capability of the Gate tool for simulating digital mammography system and the images created in it from the viewpoint of image contrast can be confirmed.

  10. Simulation of a quantum NOT gate for a single qutrit system

    Indian Academy of Sciences (India)

    level system; qutrit; three-level transitions; one-qutrit quantum gate. ... Because of the fact that the three-level atom defines a total normalized state composed of superposition of three different single-level states, it is assumed that such a system ...

  11. Stream-lined Gating Systems with Improved Yield - Dimensioning and Experimental Validation

    DEFF Research Database (Denmark)

    Tiedje, Niels Skat; Skov-Hansen, Søren Peter

    The paper describes how a stream-lined gating system where the melt is confined and controlled during filling can be designed. Commercial numerical modelling software has been used to compare the stream-lined design with a traditional gating system. These results are confirmed by experiments where...... the two types of lay-outs are cast in production. It is shown that flow in the stream-lined lay-out is well controlled and that the quality of the castings is as at least equal to that of castings produced with a traditional lay-out. Further, the yield is improved by 4 % relative to a traditional lay-out....

  12. Gate valve and shutter control system of the fusion experiment Wendelstein 7-X

    Energy Technology Data Exchange (ETDEWEB)

    Schacht, Jörg, E-mail: joerg.schacht@ipp.mpg.de [Max Planck Institute for Plasma Physics, Wendelsteinstrasse 1, Greifswald (Germany); Pingel, Steffen; Wölk, Andreas [Max Planck Institute for Plasma Physics, Wendelsteinstrasse 1, Greifswald (Germany); Raußeck, Ronald [University of Freiberg, Freiberg (Germany)

    2014-05-15

    Highlights: • Shown in this paper is the implementation of the W7-X CoDaC concept for the technical component gate valve and shutter control system for the experiment Wendelstein 7-X. • It explains the field, process and supervision level. • The paper contains descriptions of the slow control and stations and the pneumatic scheme for controlling a gate valve or a shutter device. • It introduces the HMI for supervision and controlling the whole component or the control modules. - Abstract: The plasma vessel of the fusion experiment Wendelstein 7-X (W7-X) is a plasma vessel covering a plasma volume of about 30 m{sup 3}. The vacuum conditions for plasma experiments inside the plasma vessel are supposed to be in a range of 1 × 10{sup −8} mbar (ultra high vacuum conditions) after evacuation and conditioning. The 254 ports of the plasma vessel allow an external access to the inner space of the plasma vessel. Ports for heating and diagnostic systems are equipped with gate valves or with shutters. The vacuum gate valves are used as a controllable mechanical and a vacuum disconnection point between diagnostics and heating systems on the port side and the inner plasma vessel on the other side. The shutters are responsible for an optical and thermal protection for port windows or installed equipments inside the ports. After an overview of the main requirements for the control of the huge number of gate valves and shutters for the operational phases 1 and 2 of W7-X the design and realization of a centralized control system for controlling and observing all shutters and the majority of gate valves of the machine Wendelstein 7-X will be introduced and discussed.

  13. BIG DIPPER. The first gating-free dynamic micro-CT system design

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Ge [Virginia Tech, Blacksburg, VA (United States). Biomedical Imaging Div.; Ritman, Erik L. [Mayo Clinic, Rochester, MN (United States). Dept. of Physiology; Yu, Hengyong [Wake Forest Univ., Winston-Salem, NC (United States). Dept. of Radiology and Biomedical Imaging Div.

    2011-07-01

    In contrast to the current 'ultrafast' micro-CT systems that scan over many cardiac and respiratory cycles aided by gating at high dose, here our biomedical imaging group (BIG) proposes the architecture and specifications for Dynamic Interior Pulsed Plural-sourcE Rotating-gantry (DIPPER) micro-CT. This patent-pending gating-free scanner targets volumetric micro-CT of a 2cm diameter ROI with 50ms scan speed and 100{mu}m voxel resolution at reduced radiation dose. In this paper, both the biological rationale and physical feasibility are presented. Numerical results are included as well, assuming a 7-source symmetric arrangement. (orig.)

  14. Somatosensory Gating Is Dependent on the Rate of Force Recruitment in the Human Orofacial System

    Science.gov (United States)

    Andreatta, Richard D.; Barlow, Steven M.

    2009-01-01

    Purpose: Functional orofacial behaviors vary in their force endpoint and rate of recruitment. This study assessed the gating of orofacial cutaneous somatosensation during different cyclic lip force recruitment rates. Understanding how differences in the rate of force recruitment influences trigeminal system function is an important step toward…

  15. System-bath correlation function probed by conventional and time-gated stimulated photon echo

    NARCIS (Netherlands)

    Boeij, Wim P. de; Pshenichnikov, Maxim S.; Wiersma, Douwe A.

    1996-01-01

    We show how in the framework of the multimode Brownian oscillator model the system-bath correlation function can be derived from conventional and time-gated stimulated photon echo experiments and consideration of the linear optical spectra. Experiments are performed on the infrared dye DTTCI in room

  16. Consideration of the accuracy by variation of respiration in real-time position management respiratory gating system

    International Nuclear Information System (INIS)

    Na, Jun Young; Kang, Tae Young; Beak, Geum Mun; Kwon, Gyeong Tae

    2013-01-01

    Respiratory Gated Radiation Therapy (RGRT) has been carried out using RPM (Real-time Position Management) Respiratory Gating System (version 1.7.5, varian, USA) in Asan Medical Center. This study was to analyze and evaluate the accuracy of Respiratory Gated Radiation Therapy (RGRT) according to variation of respiration. Making variation of respiration using Motion Phantom:QUASAR Programmable Respiratory Motion Phantom (Moudus Medical Device Inc. CANADA) able to adjust respiration pattern randomly was varying period, amplitude and baseline by analyze 50 patient's respiration of lung and liver cancer. One of the variations of respiration is baseline shift gradually downward per 0.01 cm, 0.03 cm, 0.05 cm. The other variation of respiration is baseline shift accidently downward per 0.2 cm, 0.4 cm, 0.6 cm, 0.8 cm. Experiments were performed in the same way that is used RPM Respiratory Gating System (phase gating, usually 30-70% gating) in Asan Medical Center. It was all exposed radiation under one of the conditions of baseline shift gradually downward per 0.01 cm, 0.03 cm, 0.05 cm. Under the other condition of baseline shift accidently downward per 0.2 cm, 0.4 cm, 0.6 cm, 0.8 cm equally radiation was exposed. The variations of baseline shifts didn't accurately reflect on phase gating in RPM Respiratory Gating System. This inexactitude makes serious uncertainty in Respiratory Gated Radiation Therapy. So, Must be stabilized breathing of patient before conducting Respiratory Gated Radiation Therapy. also must be monitored breathing of patient in the middle of treatment. If you observe considerable changes of breathing when conducting Respiratory Gated Radiation Therapy. Stopping treatment immediately and then must be need to recheck treatment site using fluoroscopy. If patient's respiration rechecked using fluoroscopy restabilize, it is possible to restart Respiratory Gated Radiation Therapy

  17. Research on remote-controlling gate-ban system based on embedded system and GSM

    Science.gov (United States)

    Chen, Yuelin; Sun, Liangbo

    2009-07-01

    Nowadays the Gate-Ban Controlling System mainly uses the MCU as the control center, but the MCU has some disadvantages such as lower reliability and less expandability. Aims at resolving these problems, analyzes the modules' construction and designs the hardware platform and software platform of the system, develops the video collection functions at the supervising terminal based on Linux system, uses ARM as the control center and gets the information from extended ports by ARM control panel, and then transports them in SMS by using GPRS platform, at last the wireless long-distance supervise and control can be achieved. In the experiment the results show that the method proposed in this paper has good reliability and expansibility.

  18. Remediation of transuranic-contaminated coral soil at Johnston Atoll using the segmented gate system

    International Nuclear Information System (INIS)

    Bramlitt, E.; Johnson, N.

    1994-01-01

    Thermo Analytical, Inc. (TMA) has developed a system to remove clean soil from contaminated soil. The system consists of a soil conveyor, an array of radiation detectors toward the conveyor feed end, a gate assembly at the conveyor discharge end, and two additional conveyors which move discharged soil to one or another paths. The gate assembly is as wide as the ''sorter conveyor,'' and it has eight individual gates or segments. The segments automatically open or close depending on the amount of radioactivity present. In one position they pass soil to a clean soil conveyor, and in the other position they let soil fall to a hot soil conveyor. The soil sorting process recovers clean soil for beneficial use and it substantially reduces the quantity of soil which must be decontaminated or prepared for waste disposal. The Segmented Gate System (SGS) was developed for the cleanup of soil contaminated with some transuranium elements at Johnston Atoll. It has proven to be an effective means for recovering clean soil and verifying that soil is clean, minimizing the quantity of truly contaminated soil, and providing measures of contamination for waste transport and disposal. TMA is constructing a small, transportable soil cleanup as it is confident the SGS technology can be adapted to soils and contaminants other than those at Johnston Atoll. It will use this transportable plant to demonstrate the technology and to develop site specific parameters for use in designing plants to meet cleanup needs

  19. Why military personnel fail to keep medical appointments.

    Science.gov (United States)

    Thornton, R; Ballard, K

    2008-03-01

    frequently being on exercise at the time of their appointment. Demographic differences such as age and gender, and practical factors such as appointment day, distance travelled, method of appointment notification, or type of hospital were not found to be associated with attendance. The most common reasons for not attending appointments were due to administrative error and an inability amongst patients to recall the correct date of the appointment. Whilst efforts to improve attendance through various reminder systems have been found to be effective in the short term at least, improvements in the efficiency of appointment administration is likely to generate a reduction in DNA and in turn will reduce the wastage of resources.

  20. 77 FR 58424 - Drucker, Inc., DynaMotive Energy Systems Corp., and Gate to Wire Solutions, Inc., Order of...

    Science.gov (United States)

    2012-09-20

    ... From the Federal Register Online via the Government Publishing Office SECURITIES AND EXCHANGE COMMISSION Drucker, Inc., DynaMotive Energy Systems Corp., and Gate to Wire Solutions, Inc., Order of... current and accurate information concerning the securities of Gate to Wire Solutions, Inc. because it has...

  1. Directors General appointed

    CERN Multimedia

    1975-01-01

    At a special session on 21 March, presided over by P. Levaux, the Council of the European Organization for Nuclear Research appointed J . B. Adams and L . Van Hove as Directors General of the Organization for a period of five years beginning 1 January 1976. Dr. Adams will be responsible for the administration of CERN, for the operation of the equipment and services and for the construction of buildings and major equipment. Professor Van Hove will be responsible for the research activities of the Organization.

  2. A simple laser locking system based on a field-programmable gate array

    DEFF Research Database (Denmark)

    Jørgensen, Nils Byg; Birkmose, Danny Matthiesen; Trelborg, Kristian

    2016-01-01

    Frequency stabilization of laser light is crucial in both scientific and industrial applications. Technological developments now allow analog laser stabilization systems to be replaced with digital electronics such as field-programmable gate arrays, which have recently been utilized to develop su...... were performed to characterize the system. The linewidth of the locked laser was measured to be 0.7±0.1 MHz with a settling time of 10 ms. The system can thus fully match laser systems currently in use for atom trapping and cooling applications.......Frequency stabilization of laser light is crucial in both scientific and industrial applications. Technological developments now allow analog laser stabilization systems to be replaced with digital electronics such as field-programmable gate arrays, which have recently been utilized to develop......-integral-derivative controller are programmed on the field-programmable gate array and only minimal additional components are required to frequency stabilize a laser. The locking system is administered from a host-computer which provides comprehensive, long-distance control through a versatile interface. Various measurements...

  3. Fault Tree Analysis with Temporal Gates and Model Checking Technique for Qualitative System Safety Analysis

    International Nuclear Information System (INIS)

    Koh, Kwang Yong; Seong, Poong Hyun

    2010-01-01

    Fault tree analysis (FTA) has suffered from several drawbacks such that it uses only static gates and hence can not capture dynamic behaviors of the complex system precisely, and it is in lack of rigorous semantics, and reasoning process which is to check whether basic events really cause top events is done manually and hence very labor-intensive and time-consuming for the complex systems while it has been one of the most widely used safety analysis technique in nuclear industry. Although several attempts have been made to overcome this problem, they can not still do absolute or actual time modeling because they adapt relative time concept and can capture only sequential behaviors of the system. In this work, to resolve the problems, FTA and model checking are integrated to provide formal, automated and qualitative assistance to informal and/or quantitative safety analysis. Our approach proposes to build a formal model of the system together with fault trees. We introduce several temporal gates based on timed computational tree logic (TCTL) to capture absolute time behaviors of the system and to give concrete semantics to fault tree gates to reduce errors during the analysis, and use model checking technique to automate the reasoning process of FTA

  4. Model-based restoration using light vein for range-gated imaging systems.

    Science.gov (United States)

    Wang, Canjin; Sun, Tao; Wang, Tingfeng; Wang, Rui; Guo, Jin; Tian, Yuzhen

    2016-09-10

    The images captured by an airborne range-gated imaging system are degraded by many factors, such as light scattering, noise, defocus of the optical system, atmospheric disturbances, platform vibrations, and so on. The characteristics of low illumination, few details, and high noise make the state-of-the-art restoration method fail. In this paper, we present a restoration method especially for range-gated imaging systems. The degradation process is divided into two parts: the static part and the dynamic part. For the static part, we establish the physical model of the imaging system according to the laser transmission theory, and estimate the static point spread function (PSF). For the dynamic part, a so-called light vein feature extraction method is presented to estimate the fuzzy parameter of the atmospheric disturbance and platform movement, which make contributions to the dynamic PSF. Finally, combined with the static and dynamic PSF, an iterative updating framework is used to restore the image. Compared with the state-of-the-art methods, the proposed method can effectively suppress ringing artifacts and achieve better performance in a range-gated imaging system.

  5. Factors affecting adherence to appointment system in the clinic for non-communicable diseases in UNRWA's Khan Younis Health Centre and the role of mobile phone text messages to improve adherence: a descriptive cross-sectional study.

    Science.gov (United States)

    Al Najjar, Sanaa; Al Shaer, Tamer

    2018-02-21

    To meet the emerging needs of the increasing numbers of patients with non-communicable diseases and to provide optimum care with optimum contact time and minimum waiting time, as stated in UNRWA guidelines, the mobile phone text messaging system was implemented in UNRWA centres to remind patients of upcoming appointments and to thereby improve the quality of care for vulnerable patients and regulate the work load in the clinics for non-communicable diseases. The aim of this study was to assess the causes for lack of adherence to the appointment system at UNRWA centres. This descriptive cross-sectional study was done in the UNRWA's Khan Younis Health Centre (KYHC), which serves the same refugee population as other UNRWA health centres and follows the same guidelines with minimal variation. Data were collected through interviewer-administered questionnaires, with ten medical staff members involved in the appointment process and 50 patients with non-communicable diseases selected randomly from patients attending the KYHC. The text-message reminder intervention targeted 1000 patients with non-communicable diseases and consisted of an electronic message technique that was developed to remind patients about the day and time of upcoming appointments. Administrative approval was obtained from the chief of UNRWA health programme. Verbal consent was obtained from participants. We followed the Modified International Code of Ethics Principles (1975), known as the Declaration of Helsinki. The main barrier to adherence to appointments in the clinic for non-communicable diseases was forgetting the appointment. Other factors were lack of awareness, clinic overcrowding, appointments that do not match the patient's preference, availability of other service providers, and financial issues. In March, 2016, after the completion of the intervention, the proportion of patients that adhered to their appointment by date and time was 76%, compared with about 45% in January and February

  6. Distribution and function of voltage-gated sodium channels in the nervous system.

    Science.gov (United States)

    Wang, Jun; Ou, Shao-Wu; Wang, Yun-Jie

    2017-11-02

    Voltage-gated sodium channels (VGSCs) are the basic ion channels for neuronal excitability, which are crucial for the resting potential and the generation and propagation of action potentials in neurons. To date, at least nine distinct sodium channel isoforms have been detected in the nervous system. Recent studies have identified that voltage-gated sodium channels not only play an essential role in the normal electrophysiological activities of neurons but also have a close relationship with neurological diseases. In this study, the latest research findings regarding the structure, type, distribution, and function of VGSCs in the nervous system and their relationship to neurological diseases, such as epilepsy, neuropathic pain, brain tumors, neural trauma, and multiple sclerosis, are reviewed in detail.

  7. Batch arrival discrete time queue with gated vacation system ...

    African Journals Online (AJOL)

    A class of single server vacation queues, which have batch arrivals and single server, is considered in discrete time. Here the server goes on vacation of random length as soon as the system becomes empty. On return from vacation, if he finds any customers waiting in the queue, the server starts serving the customers one ...

  8. AIP appoints New CEO

    Science.gov (United States)

    The American Institute of Physics (AIP) has announced the appointment of a new chief executive officer, Kenneth W. Ford, who is to succeed H. William Koch when Koch retires on March 28, 1987. Koch has held the position since 1966.AIP is a not-for-profit scientific organization made up of 10 member societies, including AGU, that represent more than 90,000 scientists. Its main activities include scientific publishing and marketing of 76 primary physics journals, including translations of foreign journals, books, conference proceedings, and the magazine Physics Today. AIP also is involved with electronic abstracting and other scientific communications and has active programs in education, public information, manpower statistics, and the history of physics.

  9. Development of a Compact Range-gated Vision System to Monitor Structures in Low-visibility Environments

    International Nuclear Information System (INIS)

    Ahn, Yong-Jin; Park, Seung-Kyu; Baik, Sung-Hoon; Kim, Dong-Lyul; Choi, Young-Soo; Jeong, Kyung-Min

    2015-01-01

    Image acquisition in disaster area or radiation area of nuclear industry is an important function for safety inspection and preparing appropriate damage control plans. So, automatic vision system to monitor structures and facilities in blurred smoking environments such as the places of a fire and detonation is essential. Vision systems can't acquire an image when the illumination light is blocked by disturbance materials, such as smoke, fog and dust. To overcome the imaging distortion caused by obstacle materials, robust vision systems should have extra-functions, such as active illumination through disturbance materials. One of active vision system is a range-gated imaging system. The vision system based on the range-gated imaging system can acquire image data from the blurred and darken light environments. Range-gated imaging (RGI) is a direct active visualization technique using a highly sensitive image sensor and a high intensity illuminant. Currently, the range-gated imaging technique providing 2D and range image data is one of emerging active vision technologies. The range-gated imaging system gets vision information by summing time sliced vision images. In the RGI system, a high intensity illuminant illuminates for ultra-short time and a highly sensitive image sensor is gated by ultra-short exposure time to only get the illumination light. Here, the illuminant illuminates objects by flashing strong light through disturbance materials, such as smoke particles and dust particles. In contrast to passive conventional vision systems, the RGI active vision technology enables operation even in harsh environments like low-visibility smoky environment. In this paper, a compact range-gated vision system is developed to monitor structures in low-visibility environment. The system consists of illumination light, a range-gating camera and a control computer. Visualization experiments are carried out in low-visibility foggy environment to see imaging capability

  10. Improved Duct Systems Task Report with StageGate 2 Analysis

    Energy Technology Data Exchange (ETDEWEB)

    Moyer, Neil [Florida Solar Energy Center, Cocoa, FL (United States); Stroer, Dennis [Calcs-Plus, Venice, FL (United States)

    2007-12-31

    This report is about Building America Industrialized Housing Partnership's work with two industry partners, Davalier Homes and Southern Energy Homes, in constructing and evaluating prototype interior duct systems. Issues of energy performance, comfort, DAPIA approval, manufacturability and cost is addressed. A stage gate 2 analysis addresses the current status of project showing that there are still refinements needed to the process of incorporating all of the ducts within the air and thermal boundaries of the envelope.

  11. Validation of a simultaneous PET/MR system model for PET simulation using GATE

    International Nuclear Information System (INIS)

    Monnier, Florian; Fayad, Hadi; Bert, Julien; Schmidt, Holger; Visvikis, Dimitris

    2015-01-01

    Simultaneous PET/MR acquisition shows promise in a range of applications. Simulation using GATE is an essential tool that allows obtaining the ground truth for such acquisitions and therefore helping in the development and the validation of innovative processing methods such as PET image reconstruction, attenuation correction and motion correction. The purpose of this work is to validate the GATE simulation of the Siemens Biograph mMR PET/MR system. A model of the Siemens Biograph mMR was developed. This model includes the geometry and spatial positioning of the crystals inside the scanner and the characteristics of the detection process. The accuracy of the model was tested by comparing, on a real physical phantom study, GATE simulated results to reconstructed PET images using measured results obtained from a Siemens Biograph mMR system. The same parameters such as the acquisition time and phantom position inside the scanner were fixed for our simulations. List-mode outputs were recovered in both cases and reconstructed using the OPL-EM algorithm. Several parameters were used to compare the two reconstructed images such as profile comparison, signal-to-noise ratio and activity contrast analysis. Finally patient acquired MR images were segmented and used for the simulation of corresponding PET images. The simulated and acquired sets of reconstructed phantom images showed close emission values in regions of interest with relative differences lower than 5%. The scatter fraction was within a <3% agreement. Close matching of profiles and contrast indices were obtained between simulated and corresponding acquired PET images. Our results indicate that the GATE developed Biograph mMR model is accurate in comparison to the real scanner performance and can be used for evaluating innovative processing methods for applications in clinical PET/MR protocols.

  12. Validation of a simultaneous PET/MR system model for PET simulation using GATE

    Energy Technology Data Exchange (ETDEWEB)

    Monnier, Florian; Fayad, Hadi; Bert, Julien [LaTIM UMR 1101, Brest (France); Schmidt, Holger [University Hospital of Tübingen, Tübingen (Germany); Visvikis, Dimitris [LaTIM UMR 1101, Brest (France)

    2015-05-18

    Simultaneous PET/MR acquisition shows promise in a range of applications. Simulation using GATE is an essential tool that allows obtaining the ground truth for such acquisitions and therefore helping in the development and the validation of innovative processing methods such as PET image reconstruction, attenuation correction and motion correction. The purpose of this work is to validate the GATE simulation of the Siemens Biograph mMR PET/MR system. A model of the Siemens Biograph mMR was developed. This model includes the geometry and spatial positioning of the crystals inside the scanner and the characteristics of the detection process. The accuracy of the model was tested by comparing, on a real physical phantom study, GATE simulated results to reconstructed PET images using measured results obtained from a Siemens Biograph mMR system. The same parameters such as the acquisition time and phantom position inside the scanner were fixed for our simulations. List-mode outputs were recovered in both cases and reconstructed using the OPL-EM algorithm. Several parameters were used to compare the two reconstructed images such as profile comparison, signal-to-noise ratio and activity contrast analysis. Finally patient acquired MR images were segmented and used for the simulation of corresponding PET images. The simulated and acquired sets of reconstructed phantom images showed close emission values in regions of interest with relative differences lower than 5%. The scatter fraction was within a <3% agreement. Close matching of profiles and contrast indices were obtained between simulated and corresponding acquired PET images. Our results indicate that the GATE developed Biograph mMR model is accurate in comparison to the real scanner performance and can be used for evaluating innovative processing methods for applications in clinical PET/MR protocols.

  13. Prototype development of an electrical impedance based simultaneous respiratory and cardiac monitoring system for gated radiotherapy.

    Science.gov (United States)

    Kohli, Kirpal; Liu, Jeff; Schellenberg, Devin; Karvat, Anand; Parameswaran, Ash; Grewal, Parvind; Thomas, Steven

    2014-10-14

    In radiotherapy, temporary translocations of the internal organs and tumor induced by respiratory and cardiac activities can undesirably lead to significantly lower radiation dose on the targeted tumor but more harmful radiation on surrounding healthy tissues. Respiratory and cardiac gated radiotherapy offers a potential solution for the treatment of tumors located in the upper thorax. The present study focuses on the design and development of simultaneous acquisition of respiratory and cardiac signal using electrical impedance technology for use in dual gated radiotherapy. An electronic circuitry was developed for monitoring the bio-impedance change due to respiratory and cardiac motions and extracting the cardiogenic ECG signal. The system was analyzed in terms of reliability of signal acquisition, time delay, and functionality in a high energy radiation environment. The resulting signal of the system developed was also compared with the output of the commercially available Real-time Position Management™ (RPM) system in both time and frequency domains. The results demonstrate that the bioimpedance-based method can potentially provide reliable tracking of respiratory and cardiac motion in humans, alternative to currently available methods. When compared with the RPM system, the impedance-based system developed in the present study shows similar output pattern but different sensitivities in monitoring different respiratory rates. The tracking of cardiac motion was more susceptible to interference from other sources than respiratory motion but also provided synchronous output compared with the ECG signal extracted. The proposed hardware-based implementation was observed to have a worst-case time delay of approximately 33 ms for respiratory monitoring and 45 ms for cardiac monitoring. No significant effect on the functionality of the system was observed when it was tested in a radiation environment with the electrode lead wires directly exposed to high-energy X

  14. Gating system optimization of low pressure casting A356 aluminum alloy intake manifold based on numerical simulation

    Directory of Open Access Journals (Sweden)

    Jiang Wenming

    2014-03-01

    Full Text Available To eliminate the shrinkage porosity in low pressure casting of an A356 aluminum alloy intake manifold casting, numerical simulation on filling and solidification processes of the casting was carried out using the ProCAST software. The gating system of the casting is optimized according to the simulation results. Results show that when the gating system consists of only one sprue, the filling of the molten metal is not stable; and the casting does not follow the sequence solidification, and many shrinkage porosities are observed through the casting. After the gating system is improved by adding one runner and two in-gates, the filling time is prolonged from 4.0 s to 4.5 s, the filling of molten metal becomes stable, but this casting does not follow the sequence solidification either. Some shrinkage porosity is also observed in the hot spots of the casting. When the gating system was further improved by adding risers and chill to the hot spots of the casting, the shrinkage porosity defects were eliminated completely. Finally, by using the optimized gating system the A356 aluminum alloy intake manifold casting with integrated shape and smooth surface as well as dense microstructure was successfully produced.

  15. 48 CFR 1301.670 - Appointment of contracting officer's representative (COR).

    Science.gov (United States)

    2010-10-01

    ... officer's representative (COR). 1301.670 Section 1301.670 Federal Acquisition Regulations System..., Contracting Authority, and Responsibilities 1301.670 Appointment of contracting officer's representative (COR..., appointment and cancellation of CORs is described in CAM 1301.670. ...

  16. The design of RFID convey or belt gate systems using an antenna control unit.

    Science.gov (United States)

    Park, Chong Ryol; Lee, Seung Joon; Eom, Ki Hwan

    2011-01-01

    This paper proposes an efficient management system utilizing a Radio Frequency Identification (RFID) antenna control unit which is moving along with the path of boxes of materials on the conveyor belt by manipulating a motor. The proposed antenna control unit, which is driven by a motor and is located on top of the gate, has an array structure of two antennas with parallel connection. The array structure helps improve the directivity of antenna beam pattern and the readable RFID distance due to its configuration. In the experiments, as the control unit follows moving materials, the reading time has been improved by almost three-fold compared to an RFID system employing conventional fixed antennas. The proposed system also has a recognition rate of over 99% without additional antennas for detecting the sides of a box of materials. The recognition rate meets the conditions recommended by the Electronic Product Code glbal network (EPC)global for commercializing the system, with three antennas at a 20 dBm power of reader and a conveyor belt speed of 3.17 m/s. This will enable a host of new RFID conveyor belt gate systems with increased performance.

  17. The Design of RFID Conveyor Belt Gate Systems Using an Antenna Control Unit

    Directory of Open Access Journals (Sweden)

    Ki Hwan Eom

    2011-09-01

    Full Text Available This paper proposes an efficient management system utilizing a Radio Frequency Identification (RFID antenna control unit which is moving along with the path of boxes of materials on the conveyor belt by manipulating a motor. The proposed antenna control unit, which is driven by a motor and is located on top of the gate, has an array structure of two antennas with parallel connection. The array structure helps improve the directivity of antenna beam pattern and the readable RFID distance due to its configuration. In the experiments, as the control unit follows moving materials, the reading time has been improved by almost three-fold compared to an RFID system employing conventional fixed antennas. The proposed system also has a recognition rate of over 99% without additional antennas for detecting the sides of a box of materials. The recognition rate meets the conditions recommended by the Electronic Product Code glbal network (EPCglobal for commercializing the system, with three antennas at a 20 dBm power of reader and a conveyor belt speed of 3.17 m/s. This will enable a host of new RFID conveyor belt gate systems with increased performance.

  18. Optimal control of quantum gates and suppression of decoherence in a system of interacting two-level particles

    International Nuclear Information System (INIS)

    Grace, Matthew; Brif, Constantin; Rabitz, Herschel; Walmsley, Ian A; Kosut, Robert L; Lidar, Daniel A

    2007-01-01

    Methods of optimal control are applied to a model system of interacting two-level particles (e.g., spin-half atomic nuclei or electrons or two-level atoms) to produce high-fidelity quantum gates while simultaneously negating the detrimental effect of decoherence. One set of particles functions as the quantum information processor, whose evolution is controlled by a time-dependent external field. The other particles are not directly controlled and serve as an effective environment, coupling to which is the source of decoherence. The control objective is to generate target one- and two-qubit unitary gates in the presence of strong environmentally-induced decoherence and under physically motivated restrictions on the control field. The quantum-gate fidelity, expressed in terms of a novel state-independent distance measure, is maximized with respect to the control field using combined genetic and gradient algorithms. The resulting high-fidelity gates demonstrate the feasibility of precisely guiding the quantum evolution via optimal control, even when the system complexity is exacerbated by environmental coupling. It is found that the gate duration has an important effect on the control mechanism and resulting fidelity. An analysis of the sensitivity of the gate performance to random variations in the system parameters reveals a significant degree of robustness attained by the optimal control solutions

  19. Field Programmable Gate Array-based I and C Safety System

    International Nuclear Information System (INIS)

    Kim, Hyun Jeong; Kim, Koh Eun; Kim, Young Geul; Kwon, Jong Soo

    2014-01-01

    Programmable Logic Controller (PLC)-based I and C safety system used in the operating nuclear power plants has the disadvantages of the Common Cause Failure (CCF), high maintenance costs and quick obsolescence, and then it is necessary to develop the other platform to replace the PLC. The Field Programmable Gate Array (FPGA)-based Instrument and Control (I and C) safety system is safer and more economical than Programmable Logic Controller (PLC)-based I and C safety system. Therefore, in the future, FPGA-based I and C safety system will be able to replace the PLC-based I and C safety system in the operating and the new nuclear power plants to get benefited from its safety and economic advantage. FPGA-based I and C safety system shall be implemented and verified by applying the related requirements to perform the safety function

  20. A hydroxyl radical detection system using gas expansion and fast gating laser-induced fluorescence techniques.

    Science.gov (United States)

    Chen, Hao; Hu, Renzhi; Xie, Pinhua; Xing, Xingbiao; Ling, Liuyi; Li, Zhiyan; Wang, Fengyang; Wang, Yihui; Liu, Jianguo; Liu, Wenqing

    2018-03-01

    An OH radical measurement instrument based on Fluorescence Assay by Gas Expansion (FAGE) has been developed in our laboratory. Ambient air is introduced into a low-pressure fluorescence cell through a pinhole aperture and irradiated by a dye laser at a high repetition rate of 8.5kHz. The OH radical is both excited and detected at 308nm using A-X(0,0) band. To satisfy the high efficiency needs of fluorescence collection and detection, a 4-lens optical system and a self-designed gated photomultiplier (PMT) is used, and gating is actualized by switching the voltage applied on the PMT dynodes. A micro channel photomultiplier (MCP) is also prepared for fluorescence detection. Then the weak signal is accumulated by a photon counter in a specific timing. The OH radical excitation spectrum range in the wavelength of 307.82-308.2nm is detected and the excited line for OH detection is determined to be Q 1 (2) line. The calibration of the FAGE system is researched by using simultaneous photolysis of H 2 O and O 2 . The minimum detection limit of the instrument using gated PMT is determined to be 9.4×10 5 molecules/cm 3 , and the sensitivity is 9.5×10 -7 cps/(OH·cm -3 ), with a signal-to-noise ratio of 2 and an integration time of 60sec, while OH detection limit and the detection sensitivity using MCP is calculated to be 1.6×10 5 molecules/cm 3 and 2.3×10 -6 cps/(OH·cm -3 ). The laboratory OH radical measurement is carried out and results show that the proposed system can be used for atmospheric OH radical measurement. Copyright © 2017. Published by Elsevier B.V.

  1. Quantum iSWAP gate in optical cavities with a cyclic three-level system

    Science.gov (United States)

    Yan, Guo-an; Qiao, Hao-xue; Lu, Hua

    2018-04-01

    In this paper we present a scheme to directly implement the iSWAP gate by passing a cyclic three-level system across a two-mode cavity quantum electrodynamics. In the scheme, a three-level Δ -type atom ensemble prepared in its ground state mediates the interaction between the two-cavity modes. For this theoretical model, we also analyze its performance under practical noise, including spontaneous emission and the decay of the cavity modes. It is shown that our scheme may have a high fidelity under the practical noise.

  2. New appointment at the IAEA

    International Nuclear Information System (INIS)

    2000-01-01

    The document gives short information on the biography of Professor Dr. Werner Burkart from Germany who was appointed (as of July 2000) as Deputy Director General, Head of the Department of Nuclear Sciences and Applications, IAEA

  3. Application of Field Programmable Gate Arrays in Instrumentation and Control Systems of Nuclear Power Plants

    International Nuclear Information System (INIS)

    2016-01-01

    Field programmable gate arrays (FPGAs) are gaining increased attention worldwide for application in nuclear power plant (NPP) instrumentation and control (I&C) systems, particularly for safety and safety related applications, but also for non-safety ones. NPP operators and equipment suppliers see potential advantages of FPGA based digital I&C systems as compared to microprocessor based applications. This is because FPGA based systems can be made simpler, more testable and less reliant on complex software (e.g. operating systems), and are easier to qualify for safety and safety related applications. This publication results from IAEA consultancy meetings covering the various aspects, including design, qualification, implementation, licensing, and operation, of FPGA based I&C systems in NPPs

  4. Range-Image Acquisition for Discriminated Objects in a Range-gated Robot Vision System

    Energy Technology Data Exchange (ETDEWEB)

    Park, Seung-Kyu; Ahn, Yong-Jin; Park, Nak-Kyu; Baik, Sung-Hoon; Choi, Young-Soo; Jeong, Kyung-Min [KAERI, Daejeon (Korea, Republic of)

    2015-05-15

    The imaging capability of a surveillance vision system from harsh low-visibility environments such as in fire and detonation areas is a key function to monitor the safety of the facilities. 2D and range image data acquired from low-visibility environment are important data to assess the safety and prepare appropriate countermeasures. Passive vision systems, such as conventional camera and binocular stereo vision systems usually cannot acquire image information when the reflected light is highly scattered and absorbed by airborne particles such as fog. In addition, the image resolution captured through low-density airborne particles is decreased because the image is blurred and dimmed by the scattering, emission and absorption. Active vision systems, such as structured light vision and projected stereo vision are usually more robust for harsh environment than passive vision systems. However, the performance is considerably decreased in proportion to the density of the particles. The RGI system provides 2D and range image data from several RGI images and it moreover provides clear images from low-visibility fog and smoke environment by using the sum of time-sliced images. Nowadays, the Range-gated (RG) imaging is an emerging technology in the field of surveillance for security applications, especially in the visualization of invisible night and fog environment. Although RGI viewing was discovered in the 1960's, this technology is, nowadays becoming more applicable by virtue of the rapid development of optical and sensor technologies. Especially, this system can be adopted in robot-vision system by virtue of its compact portable configuration. In contrast to passive vision systems, this technology enables operation even in harsh environments like fog and smoke. During the past decades, several applications of this technology have been applied in target recognition and in harsh environments, such as fog, underwater vision. Also, this technology has been

  5. Range-Image Acquisition for Discriminated Objects in a Range-gated Robot Vision System

    International Nuclear Information System (INIS)

    Park, Seung-Kyu; Ahn, Yong-Jin; Park, Nak-Kyu; Baik, Sung-Hoon; Choi, Young-Soo; Jeong, Kyung-Min

    2015-01-01

    The imaging capability of a surveillance vision system from harsh low-visibility environments such as in fire and detonation areas is a key function to monitor the safety of the facilities. 2D and range image data acquired from low-visibility environment are important data to assess the safety and prepare appropriate countermeasures. Passive vision systems, such as conventional camera and binocular stereo vision systems usually cannot acquire image information when the reflected light is highly scattered and absorbed by airborne particles such as fog. In addition, the image resolution captured through low-density airborne particles is decreased because the image is blurred and dimmed by the scattering, emission and absorption. Active vision systems, such as structured light vision and projected stereo vision are usually more robust for harsh environment than passive vision systems. However, the performance is considerably decreased in proportion to the density of the particles. The RGI system provides 2D and range image data from several RGI images and it moreover provides clear images from low-visibility fog and smoke environment by using the sum of time-sliced images. Nowadays, the Range-gated (RG) imaging is an emerging technology in the field of surveillance for security applications, especially in the visualization of invisible night and fog environment. Although RGI viewing was discovered in the 1960's, this technology is, nowadays becoming more applicable by virtue of the rapid development of optical and sensor technologies. Especially, this system can be adopted in robot-vision system by virtue of its compact portable configuration. In contrast to passive vision systems, this technology enables operation even in harsh environments like fog and smoke. During the past decades, several applications of this technology have been applied in target recognition and in harsh environments, such as fog, underwater vision. Also, this technology has been

  6. Gating Technology for Vertically Parted Green Sand Moulds

    DEFF Research Database (Denmark)

    Larsen, Per

    Gating technology for vertically parted green sand moulds. Literature study of different ways of designing gating systems.......Gating technology for vertically parted green sand moulds. Literature study of different ways of designing gating systems....

  7. Development of measurement system for radiation effect on static random access memory based field programmable gate array

    International Nuclear Information System (INIS)

    Yao Zhibin; He Baoping; Zhang Fengqi; Guo Hongxia; Luo Yinhong; Wang Yuanming; Zhang Keying

    2009-01-01

    Based on the detailed investigation in field programmable gate array(FPGA) radiation effects theory, a measurement system for radiation effects on static random access memory(SRAM)-based FPGA was developed. The testing principle of internal memory, function and power current was introduced. The hardware and software implement means of system were presented. Some important parameters for radiation effects on SRAM-based FPGA, such as configuration RAM upset section, block RAM upset section, function fault section and single event latchup section can be gained with this system. The transmission distance of the system can be over 50 m and the maximum number of tested gates can reach one million. (authors)

  8. ABOUT THE WAYS OF THE SYSTEM ANALYSIS OF METAL MOVEMENT IN GATING SYSTEMS BASED ON THE NUMERICAL SOLUTIONS OF NAVIER-STOKES EQUATIONS

    Directory of Open Access Journals (Sweden)

    S. G. Lizouzov

    2014-01-01

    Full Text Available Numerical modeling of distribution of the fields of speeds projections on axes X, Y, Z in gating system with the casting “Case of conical pair” for various temporal values is carried out. Numerical criteria for assessment of metal movement through the feeders having various spatial location relative to the gating system are offered. Dynamics of change of the offered criteria on the basis of integral average value of the speed component on axes X, Y, Z in the gating systems at the outlet from feeder is calculated.

  9. Designing cyclic appointment schedules for outpatient clinics with scheduled and unscheduled patient arrivals

    NARCIS (Netherlands)

    Kortbeek, Nikky; Zonderland, Maartje Elisabeth; Braaksma, Aleida; Vliegen, Ingrid M.H.; Boucherie, Richardus J.; Litvak, Nelli; Hans, Elias W.

    2014-01-01

    We present a methodology to design appointment systems for outpatient clinics and diagnostic facilities that offer both walk-in and scheduled service. The developed blueprint for the appointment schedule prescribes the number of appointments to plan per day and the moment on the day to schedule the

  10. Performance of an X-ray spectroscopic system based on a double-gate double-feedback charge preamplifier

    Energy Technology Data Exchange (ETDEWEB)

    Fazzi, A. E-mail: alberto.fazzi@polimi.it; Rehak, P

    2000-01-11

    The performance of a near room temperature X-ray spectroscopic system is reported. The system is based on a charge preamplifier with the first transistor having two separated gates. The preamplifier operates in a continuous reset mode without any physical resistor connected to the input node. The leakage current and the current due to the rate of X-rays is neutralized by an average current of holes, flowing under the control of an additional feedback, from the bottom to the top gate. The preamplifier is followed by a simple circuit which exactly cancels the long tail of the impulse response of a pure double-gate preamplifier. The compensation of this tail, due to the very principle of the preamplifier's continuous reset through the double-gate mechanism, improves substantially the high-rate performance of the system. The preamplifier based on a commercially available double-gate front JFET MX-40 (MOXTEK) coupled to a silicon drift detector produced at BNL achieved ENC of 13 electrons at -30 deg. C. The analysis of the system's performance, the noise analysis and optimization are described.

  11. Qualitative Study of Foster Caregivers' Views on Adherence to Pediatric Appointments.

    Science.gov (United States)

    Schneiderman, Janet U; Kennedy, Andrea K; Sayegh, Caitlin S

    The current study is a qualitative investigation of how foster caregivers, primarily Latinos, view adherence to pediatric appointments. Our purpose was to identify how the child welfare system, pediatric clinics, and pediatric health providers serving foster children might promote appointment attendance. Participants in the study had a return appointment at an outpatient pediatric clinic that served only children in the child welfare system. Twenty-eight caregivers (13 related and 15 unrelated) participated in telephone interviews after the date of their scheduled pediatric appointment; 32% missed their return appointment. Semistructured interview guides included general questions about what promotes attending the pediatric appointment, what makes it difficult to attend the pediatric appointment, and how pediatric care affects the foster child. Analysis of qualitative data using content analysis identified three themes: (a) Multiple Methods to Attend Appointments, which included caregivers' organizational and problem-solving skills; (b) Positive Health Care Experiences, which consisted of caregivers' personal relationships with providers and staff members and clinic organization; and (c) Necessity of Pediatric Care, which included recognition of the need for health care, especially timely immunizations. All caregivers also reported that appointment reminders would be helpful. Unrelated caregivers said more often than related caregivers that appointment attendance was facilitated by clinic organization. Nonadherent caregivers more than attenders mentioned their need to solve problems to attend appointments or reschedule appointments. In summary, caregivers said they valued regular pediatric health care to treat their children's chronic conditions and prevent illnesses, but they acknowledged that their home lives were hectic and that attending scheduled appointments was sometimes difficult. Foster caregivers in this study identified the ideal pediatric clinic

  12. Grid Patient Appointment Template Design to Improve Scheduling Effectiveness

    Directory of Open Access Journals (Sweden)

    Yu-Li Huang

    2015-01-01

    Full Text Available Current outpatient delivery systems have been problematic in their ability to effectively schedule appointments and grant patients access to care. A better appointment system has demonstrated improvement on these issues. The objective of this study is to develop a grid appointment system to further improve the scheduling flexibility by determining the minimum length of appointment slots that optimizes the total costs of patient waiting, physician idling, and overtime. This minimum length is used for the patient type requiring the least amount of treatment time such as return visit (RV, and multiplications of the minimum length are for patient types with longer treatment such as new patients (NP. The results indicated that the proposed grid system adjusts to demand changes at least 15% more cost-effective when grouping two RVs into an NP or dividing an NP into two RVs compared to the base-line scheduling approaches that build around the mean treatment time.

  13. Performance of an X-ray spectroscopic system based on a double-gate double-feedback charge preamplifier

    CERN Document Server

    Fazzi, A

    2000-01-01

    The performance of a near room temperature X-ray spectroscopic system is reported. The system is based on a charge preamplifier with the first transistor having two separated gates. The preamplifier operates in a continuous reset mode without any physical resistor connected to the input node. The leakage current and the current due to the rate of X-rays is neutralized by an average current of holes, flowing under the control of an additional feedback, from the bottom to the top gate. The preamplifier is followed by a simple circuit which exactly cancels the long tail of the impulse response of a pure double-gate preamplifier. The compensation of this tail, due to the very principle of the preamplifier's continuous reset through the double-gate mechanism, improves substantially the high-rate performance of the system. The preamplifier based on a commercially available double-gate front JFET MX-40 (MOXTEK) coupled to a silicon drift detector produced at BNL achieved ENC of 13 electrons at -30 deg. C. The analys...

  14. Availability estimation of repairable systems using reliability graph with general gates (RGGG)

    International Nuclear Information System (INIS)

    Goh, Gyoung Tae

    2009-02-01

    By performing risk analysis, we may obtain sufficient information about the system to redesign it and lower the probability of the occurrence of an accident or mitigate the ensuing consequences. The concept of reliability is widely used to express risk of systems. The reliability is used for non-repairable systems. But nuclear power plant systems are repairable systems. With repairable systems, repairable components can improve the availability of a system because faults that are generated in components can be recovered. Hence, the availability of the system is more proper concept in case of repairable systems. Reliability graph with general gate (RGGG) is one of the system reliability analysis methods. The RGGG is a very intuitiveness method as compared with other methods. But the RGGG has not been applied to repairable systems yet. The objective of this study is to extend the RGGG in order to enable one to analyze repairable system. Determining the probability table for each node is a critical process to calculate the system availability in the RGGG method. Therefore finding the proper algorithms and making probability tables in various situations are the major a part of this study. The other part is an example of applying RGGG method to a real system. We find the proper algorithms and probability tables for independent repairable systems, dependent series repairable systems, and k-out-of-m (K/M) redundant parallel repairable systems in this study. We can evaluate the availability of real system using these probability tables. An example for a real system is shown in the latter part of this study. For the purpose of this analysis, the charging pumps subsystem of the chemical and volume control system (CVCS) was selected. The RGGG method extended for repairable systems has the same characteristic of intuitiveness as the original RGGG method and we can confirm that the availability analysis result from the repairable RGGG method is exact

  15. Refurbishment and upgrading of Iron Gates I Hydroelectric and Navigation System on the Danube River

    International Nuclear Information System (INIS)

    Scvortov, F.; Vasiliu, A.; Rosca, N.

    1996-01-01

    This work shows the problems of the refurbishing the hydroelectric units of the Iron Gates 1 Hydroelectric and Navigation System, operating since 1970. Their long and intensive utilization leads to the necessity of their refurbishment. One is demonstrated by detailed studies that it is sensible and efficient to perform both rehabilitation of the existent hydroelectric units and their power increasing from 175 MW to 190 MW, and prior to all these, as a first step, to install an additional hydroelectric unit (G7) for each system with a capacity of 190 MW. Complex technical and energetic-economical problems appear in realizing this objective due to the necessity of analysing a great volume of data in view of taking a correct decision. (author). 7 figs

  16. Optimization of Master Alloy Amount and Gating System Design for Ductile Cast Iron Obtain in Lost Foam Process

    Directory of Open Access Journals (Sweden)

    Just P.

    2013-09-01

    Full Text Available The paper presents the optimization of master alloy amount for the high nodular graphite yield (80-90% in cast iron obtain in lost foam process. The influence of the gating system configuration and the shape of the reaction chamber, the degree of spheroidisation cast iron was examined. Research has shown that the, optimal of master alloy amount of 1.5% by mass on casting iron. The degree of spheroidisation is also influenced by the gating system configuration. The best spheroidisation effect was obtained for liquid cast iron was fed into the reaction chamber from the bottom and discharged from the top.

  17. Tailoring an intervention to the context and system redesign related to the intervention: A case study of implementing shared medical appointments for diabetes

    Directory of Open Access Journals (Sweden)

    Lawrence Renée H

    2008-06-01

    Full Text Available Abstract Background Incorporating shared medical appointments (SMAs or group visits into clinical practice to improve care and increase efficiency has become a popular intervention, but the processes to implement and sustain them have not been well described. The purpose of this study was to describe the process of implementation of SMAs in the local context of a primary care clinic over time. Methods The setting was a primary care clinic of an urban academic medical center of the Veterans Health Administration. We performed an in-depth case analysis utilizing both an innovations framework and a nested systems framework approach. This analysis helped organize and summarize implementation and sustainability issues, specifically: the pre-SMA local context; the processes of tailoring and implementation of the intervention; and the evolution and sustainability of the intervention and its context. Results Both the improvement intervention and the local context co-adapted and evolved during implementation, ensuring sustainability. The most important promoting factors were the formation of a core team committed to quality and improvement, and the clinic leadership that was supported strongly by the team members. Tailoring had to also take into account key innovation-hindering factors, including limited resources (such as space, potential to alter longstanding patient-provider relationships, and organizational silos (disconnected groups with core team members reporting to different supervisors. Conclusion Although interventions must be designed to meet the needs of the sites in which they are implemented, specific guidance tailored to the practice environment was lacking. SMAs require complex changes that impact on care routines, collaborations, and various organizational levels. Although the SMA was not envisioned originally as a form of system redesign that would alter the context in which it was implemented, it became clear that tailoring the

  18. Mølmer-Sørensen entangling gate for cavity QED systems

    Science.gov (United States)

    Takahashi, Hiroki; Nevado, Pedro; Keller, Matthias

    2017-10-01

    The Mølmer-Sørensen gate is a state-of-the-art entangling gate in ion trap quantum computing where the gate fidelity can exceed 99%. Here we propose an analogous implementation in the setting of cavity QED. The cavity photon mode acts as the bosonic degree of freedom in the gate in contrast to that played by the phonon mode in ion traps. This is made possible by utilising cavity assisted Raman transitions interconnecting the logical qubit states embedded in a four-level energy structure, making the ‘anti-Jaynes-Cummings’ term available under the rotating-wave approximation. We identify practical sources of infidelity and discuss their effects on the gate performance. Our proposal not only demonstrates an alternative entangling gate scheme but also sheds new light on the relationship between ion traps and cavity QED, in the sense that many techniques developed in the former are transferable to the latter through our framework.

  19. Mølmer–Sørensen entangling gate for cavity QED systems

    International Nuclear Information System (INIS)

    Takahashi, Hiroki; Nevado, Pedro; Keller, Matthias

    2017-01-01

    The Mølmer–Sørensen gate is a state-of-the-art entangling gate in ion trap quantum computing where the gate fidelity can exceed 99%. Here we propose an analogous implementation in the setting of cavity QED. The cavity photon mode acts as the bosonic degree of freedom in the gate in contrast to that played by the phonon mode in ion traps. This is made possible by utilising cavity assisted Raman transitions interconnecting the logical qubit states embedded in a four-level energy structure, making the ‘anti-Jaynes–Cummings’ term available under the rotating-wave approximation. We identify practical sources of infidelity and discuss their effects on the gate performance. Our proposal not only demonstrates an alternative entangling gate scheme but also sheds new light on the relationship between ion traps and cavity QED, in the sense that many techniques developed in the former are transferable to the latter through our framework. (paper)

  20. The accelerated site technology deployment program presents the segmented gate system

    International Nuclear Information System (INIS)

    Patteson, Raymond; Maynor, Doug; Callan, Connie

    2000-01-01

    The Department of Energy (DOE) is working to accelerate the acceptance and application of innovative technologies that improve the way the nation manages its environmental remediation problems. The DOE Office of Science and Technology established the Accelerated Site Technology Deployment Program (ASTD) to help accelerate the acceptance and implementation of new and innovative soil and ground water remediation technologies. Coordinated by the Department of Energy's Idaho Office, the ASTD Program reduces many of the classic barriers to the deployment of new technologies by involving government, industry, and regulatory agencies in the assessment, implementation, and validation of innovative technologies. The paper uses the example of the Segmented Gate System (SGS) to illustrate how the ASTD program works. The SGS was used to cost effectively separate clean and contaminated soil for four different radionuclides: plutonium, uranium, thorium, and cesium. Based on those results, it has been proposed to use the SGS at seven other DOE sites across the country

  1. Peptide-gated ion channels and the simple nervous system of Hydra.

    Science.gov (United States)

    Gründer, Stefan; Assmann, Marc

    2015-02-15

    Neurons either use electrical or chemical synapses to communicate with each other. Transmitters at chemical synapses are either small molecules or neuropeptides. After binding to their receptors, transmitters elicit postsynaptic potentials, which can either be fast and transient or slow and longer lasting, depending on the type of receptor. Fast transient potentials are mediated by ionotropic receptors and slow long-lasting potentials by metabotropic receptors. Transmitters and receptors are well studied for animals with a complex nervous system such as vertebrates and insects, but much less is known for animals with a simple nervous system like Cnidaria. As cnidarians arose early in animal evolution, nervous systems might have first evolved within this group and the study of neurotransmission in cnidarians might reveal an ancient mechanism of neuronal communication. The simple nervous system of the cnidarian Hydra extensively uses neuropeptides and, recently, we cloned and functionally characterized an ion channel that is directly activated by neuropeptides of the Hydra nervous system. These results demonstrate the existence of peptide-gated ion channels in Hydra, suggesting they mediate fast transmission in its nervous system. As related channels are also present in the genomes of the cnidarian Nematostella, of placozoans and of ctenophores, it should be considered that the early nervous systems of cnidarians and ctenophores have co-opted neuropeptides for fast transmission at chemical synapses. © 2015. Published by The Company of Biologists Ltd.

  2. SU-F-T-518: Development and Characterization of a Gated Treatment System Implemented with An In-House Optical Tracking System and the Elekta Response Interface

    International Nuclear Information System (INIS)

    Barraclough, B; Park, J; Li, F; Lu, B; Li, J; Liu, C; Yan, G

    2016-01-01

    Purpose: To report the development and characterization of the first in-house gating system implemented with an optical tracking system (OTS) and the Elekta Response™ interface. Methods: The Response™ connects a patient tracking system with a linac, enabling the tracking system to control radiation delivery. The developed system uses an in-house OTS to monitor patient breathing. The OTS consists of two infrared-based cameras, tracking markers affixed on patient. It achieves gated or breath-held (BH) treatment by calling beam ON/OFF functions in the Response™ dynamic-link library (DLL). A 4D motion phantom was used to evaluate its dosimetric and time delay characteristics. Two FF- and two FFF-IMRT beams were delivered in non-gated, BH and gated mode. The sinusoidal gating signal had a 6 sec period and 15 mm amplitude. The duty cycle included 10%, 20%, 30% and 50%. The BH signal was adapted from the sinusoidal wave by inserting 15 sec BHs. Each delivery was measured with a 2D diode array (MapCHECK™) and compared with the non-gated delivery using gamma analysis (3%). The beam ON/OFF time was captured using the service graphing utility of the linac. Results: The gated treatments were successfully delivered except the 10% duty cycle. The BH delivery had perfect agreement (100%) with non-gated delivery; the agreement of gated delivery decreased from 99% to 88% as duty cycle reduced from 50% to 20%. The beam on/off delay was on average 0.25/0.06 sec. The delivery time for the 50%, 30% and 20% duty cycle increased by 29%, 71% and 139%, respectively. No dosimetric or time delay difference was noticed between FF- and FFF-IMRT beams. Conclusion: The in-house gating system was successfully developed with dosimetric and time delay characteristics in line with published results for commercial systems. It will be an important platform for further research and clinical development of gated treatment.

  3. Semaphorin6A acts as a gate keeper between the central and the peripheral nervous system

    Directory of Open Access Journals (Sweden)

    Sadhu Rejina

    2007-12-01

    Full Text Available Abstract Background During spinal cord development, expression of chicken SEMAPHORIN6A (SEMA6A is almost exclusively found in the boundary caps at the ventral motor axon exit point and at the dorsal root entry site. The boundary cap cells are derived from a population of late migrating neural crest cells. They form a transient structure at the transition zone between the peripheral nervous system (PNS and the central nervous system (CNS. Ablation of the boundary cap resulted in emigration of motoneurons from the ventral spinal cord along the ventral roots. Based on its very restricted expression in boundary cap cells, we tested for a role of Sema6A as a gate keeper between the CNS and the PNS. Results Downregulation of Sema6A in boundary cap cells by in ovo RNA interference resulted in motoneurons streaming out of the spinal cord along the ventral roots, and in the failure of dorsal roots to form and segregate properly. PlexinAs interact with class 6 semaphorins and are expressed by both motoneurons and sensory neurons. Knockdown of PlexinA1 reproduced the phenotype seen after loss of Sema6A function both at the ventral motor exit point and at the dorsal root entry site of the lumbosacral spinal cord. Loss of either PlexinA4 or Sema6D function had an effect only at the dorsal root entry site but not at the ventral motor axon exit point. Conclusion Sema6A acts as a gate keeper between the PNS and the CNS both ventrally and dorsally. It is required for the clustering of boundary cap cells at the PNS/CNS interface and, thus, prevents motoneurons from streaming out of the ventral spinal cord. At the dorsal root entry site it organizes the segregation of dorsal roots.

  4. Full modelling of the MOSAIC animal PET system based on the GATE Monte Carlo simulation code

    International Nuclear Information System (INIS)

    Merheb, C; Petegnief, Y; Talbot, J N

    2007-01-01

    Positron emission tomography (PET) systems dedicated to animal imaging are now widely used for biological studies. The scanner performance strongly depends on the design and the characteristics of the system. Many parameters must be optimized like the dimensions and type of crystals, geometry and field-of-view (FOV), sampling, electronics, lightguide, shielding, etc. Monte Carlo modelling is a powerful tool to study the effect of each of these parameters on the basis of realistic simulated data. Performance assessment in terms of spatial resolution, count rates, scatter fraction and sensitivity is an important prerequisite before the model can be used instead of real data for a reliable description of the system response function or for optimization of reconstruction algorithms. The aim of this study is to model the performance of the Philips Mosaic(TM) animal PET system using a comprehensive PET simulation code in order to understand and describe the origin of important factors that influence image quality. We use GATE, a Monte Carlo simulation toolkit for a realistic description of the ring PET model, the detectors, shielding, cap, electronic processing and dead times. We incorporate new features to adjust signal processing to the Anger logic underlying the Mosaic(TM) system. Special attention was paid to dead time and energy spectra descriptions. Sorting of simulated events in a list mode format similar to the system outputs was developed to compare experimental and simulated sensitivity and scatter fractions for different energy thresholds using various models of phantoms describing rat and mouse geometries. Count rates were compared for both cylindrical homogeneous phantoms. Simulated spatial resolution was fitted to experimental data for 18 F point sources at different locations within the FOV with an analytical blurring function for electronic processing effects. Simulated and measured sensitivities differed by less than 3%, while scatter fractions agreed

  5. Respiratory guiding system for respiratory motion management in respiratory gated radiotherapy

    International Nuclear Information System (INIS)

    Kang, Seong Hee; Kim, Dong Su; Kim, Tae Ho; Suh, Tae Suk

    2013-01-01

    Respiratory guiding systems have been shown to improve the respiratory regularity. This, in turn, improves the efficiency of synchronized moving aperture radiation therapy, and it reduces the artifacts caused by irregular breathing in imaging techniques such as four-dimensional computed tomography (4D CT), which is used for treatment planning in RGRT. We have previously developed a respiratory guiding system that incorporates an individual-specific guiding waveform, which is easy to follow for each volunteer, to improve the respiratory regularity. The present study evaluates the application of this system to improve the respiratory regularity for respiratory-gated radiation therapy (RGRT). In this study, we evaluated the effectiveness of an in-house-developed respiratory guiding system incorporating an individual specific guiding waveform to improve the respiratory regularity for RGRT. Most volunteers showed significantly less residual motion at each phase during guided breathing owing to the improvement in respiratory regularity. Therefore, the respiratory guiding system can clearly reduce the residual, or respiratory, motion in each phase. From the result, the CTV and the PTV margins during RGRT can be reduced by using the respiratory guiding system, which reduces the residual motions, thus improving the accuracy of RGRT

  6. A group randomized trial using an appointment system to improve adherence to ART at reproductive and child health clinics implementing Option B+ in Tanzania.

    OpenAIRE

    Ross-Degnan, Dennis; Chalker, John; Liana, Jafary; Kajoka, Mwikemo Deborah; Valimba, Richard; Kimatta, Suleiman; Dillip, Angel; Vialle-Valentin, Catherine; Embrey, Martha; Lieber, Rachel; Johnson, Keith

    2017-01-01

    Introduction: In October 2013, Tanzania adopted Option B+ under which HIV-positive pregnant women are initiated on antiretroviral therapy in reproductive and child health clinics at diagnosis. Studies have shown that adherence and retention to antiretroviral treatment can be problematic. Methods: We implemented a group randomized controlled trial in 24 reproductive and child health clinics in eight districts in Mbeya region. The trial tested the impact of implementing paper-based appointment ...

  7. Development of a protection system for research reactor based in Field Programmable Gate Array - FPGA

    International Nuclear Information System (INIS)

    Martins, Roque Hudson da Silva

    2016-01-01

    This study presents a implementation purpose of a protection system for research nuclear reactors by using a programed device FPGA (Field Programmable Gate Array). As well as logic protection method involved on an automatic shutdown (TRIP) of a reactor, that ensure the security on such systems. These new control and operation mechanics are developed to guarantee that the security limits of a power plant are not exceeded, these mechanics can work isolated or in groups to safe guard the security levels. For this implementation to be completed, there will be presented the main aspects and concepts referred to protection systems, mostly about research nuclear reactors, with some applications terms exposed. The system proposed at this paper was developed following the VHDL (Very High Speed Integrated Circuits) hardware describing language, and the Modelsim software from Altera Software to program the automatic turning off routines, and hypothetical simulations for such. The results show that for every software application for supporting nuclear reactors, like security devices, they have to meet the IEC 60880 criteria. This paper have great importance, seeing that nuclear reactor security systems, are a basic element for ensure the reactor security. (author)

  8. Liquid gating elastomeric porous system with dynamically controllable gas/liquid transport

    Science.gov (United States)

    Sheng, Zhizhi; Wang, Honglong; Tang, Yongliang; Wang, Miao; Huang, Lizhi; Min, Lingli; Meng, Haiqiang; Chen, Songyue; Jiang, Lei; Hou, Xu

    2018-01-01

    The development of membrane technology is central to fields ranging from resource harvesting to medicine, but the existing designs are unable to handle the complex sorting of multiphase substances required for many systems. Especially, the dynamic multiphase transport and separation under a steady-state applied pressure have great benefits for membrane science, but have not been realized at present. Moreover, the incorporation of precisely dynamic control with avoidance of contamination of membranes remains elusive. We show a versatile strategy for creating elastomeric microporous membrane-based systems that can finely control and dynamically modulate the sorting of a wide range of gases and liquids under a steady-state applied pressure, nearly eliminate fouling, and can be easily applied over many size scales, pressures, and environments. Experiments and theoretical calculation demonstrate the stability of our system and the tunability of the critical pressure. Dynamic transport of gas and liquid can be achieved through our gating interfacial design and the controllable pores’ deformation without changing the applied pressure. Therefore, we believe that this system will bring new opportunities for many applications, such as gas-involved chemical reactions, fuel cells, multiphase separation, multiphase flow, multiphase microreactors, colloidal particle synthesis, and sizing nano/microparticles. PMID:29487906

  9. Linear gate

    International Nuclear Information System (INIS)

    Suwono.

    1978-01-01

    A linear gate providing a variable gate duration from 0,40μsec to 4μsec was developed. The electronic circuity consists of a linear circuit and an enable circuit. The input signal can be either unipolar or bipolar. If the input signal is bipolar, the negative portion will be filtered. The operation of the linear gate is controlled by the application of a positive enable pulse. (author)

  10. Technical Note: Evaluation of the latency and the beam characteristics of a respiratory gating system using an Elekta linear accelerator and a respiratory indicator device, Abches.

    Science.gov (United States)

    Saito, Masahide; Sano, Naoki; Ueda, Koji; Shibata, Yuki; Kuriyama, Kengo; Komiyama, Takafumi; Marino, Kan; Aoki, Shinichi; Onishi, Hiroshi

    2018-01-01

    To evaluate the basic performance of a respiratory gating system using an Elekta linac and an Abches respiratory-monitoring device. The gating system was comprised of an Elekta Synergy linac equipped with a Response TM gating interface module and an Abches respiratory-monitoring device. The latencies from a reference respiratory signal to the resulting Abches gating output signal and the resulting monitor-ion-chamber output signal were measured. Then, the flatness and symmetry of the gated beams were measured using a two-dimensional ionization chamber array for fixed and arc beams, respectively. Furthermore, the beam quality, TPR 20,10 , and the output of the fixed gated beams were also measured using a Farmer chamber. Each of the beam characteristics was compared with each of those for nongated irradiation. The full latencies at beam-on and beam-off for 6-MV gated beams were 336.4 ± 23.4 ms and 87.6 ± 7.1 ms, respectively. The differences in flatness between the gated and nongated beams were within 0.91% and 0.87% for the gun-target and left-right directions, respectively. In the same manner, the beam symmetries were within 0.68% and 0.82%, respectively. The percentage differences in beam quality and beam output were below 1% for a beam-on time range of 1.1-7 s. The latency of the Elekta gating system combined with Abches was found to be acceptable using our measurement method. Furthermore, we demonstrated that the beam characteristics of the gating system using our respiratory indicator were comparable with the nongated beams for a single-arc gated beam delivery. © 2017 American Association of Physicists in Medicine.

  11. The impact of the hydropower system Iron Gates on the environment

    International Nuclear Information System (INIS)

    Ionita, Veronica

    1997-01-01

    The paper presents studies on the impact of the hydropower system Iron Gates on the environment, stressing on the anthropic factors influencing the geophysical and biological environment. As anthropic factors we have considered, especially, generation of electric power, causing reduced pollution as compared to the fossil fuelled power generation, low primary energy consumption in the hydroelectric power plants as compared to the fossil fuelled power plants, quality of power and power cost lower than the average cost within Romanian Electricity Authority, RENEL. Local economic effects on forestry, pisciculture, transportation system, etc. are also considered. The socio-economic effects on population dynamics, labour force, agricultural land use, historical and art monuments, tourism and leisure, aesthetics and scenery, protection against natural risks are discussed. The impact on the geophysical environment takes into consideration the erosion of river beds and banks, alluvial deposits transportation, stability of slopes, underwater levels and microclimate changes. The analysis of the impact on the biological environment envisages elements regarding water quality pointing to the sources of pollution, flora and fauna. The work concludes with the procedures undertaken in order to reduce the unfavourable impact of the hydropower system on the environment. (author)

  12. Using field programmable gate array hardware for the performance improvement of ultrasonic wave propagation imaging system

    International Nuclear Information System (INIS)

    Shan, Jaffry Syed; Abbas, Syed Haider; Lee, Jung Ryul; Kang, Dong Hoon

    2015-01-01

    Recently, wave propagation imaging based on laser scanning-generated elastic waves has been intensively used for nondestructive inspection. However, the proficiency of the conventional software based system reduces when the scan area is large since the processing time increases significantly due to unavoidable processor multitasking, where computing resources are shared with multiple processes. Hence, the field programmable gate array (FPGA) was introduced for a wave propagation imaging method in order to obtain extreme processing time reduction. An FPGA board was used for the design, implementing post-processing ultrasonic wave propagation imaging (UWPI). The results were compared with the conventional system and considerable improvement was observed, with at least 78% (scanning of 100x100mm 2 with 0.5 mm interval) to 87.5% (scanning of 200x200mm 2 with 0.5 mm interval) less processing time, strengthening the claim for the research. This new concept to implement FPGA technology into the UPI system will act as a break-through technology for full-scale automatic inspection

  13. Using field programmable gate array hardware for the performance improvement of ultrasonic wave propagation imaging system

    Energy Technology Data Exchange (ETDEWEB)

    Shan, Jaffry Syed [Hamdard University, Karachi (Pakistan); Abbas, Syed Haider; Lee, Jung Ryul [Dept. of Aerospace Engineering, Korea Advanced Institute of Science and Technology, Daejeon (Korea, Republic of); Kang, Dong Hoon [Advanced Materials Research Team, Korea Railroad Research Institute, Uiwang (Korea, Republic of)

    2015-12-15

    Recently, wave propagation imaging based on laser scanning-generated elastic waves has been intensively used for nondestructive inspection. However, the proficiency of the conventional software based system reduces when the scan area is large since the processing time increases significantly due to unavoidable processor multitasking, where computing resources are shared with multiple processes. Hence, the field programmable gate array (FPGA) was introduced for a wave propagation imaging method in order to obtain extreme processing time reduction. An FPGA board was used for the design, implementing post-processing ultrasonic wave propagation imaging (UWPI). The results were compared with the conventional system and considerable improvement was observed, with at least 78% (scanning of 100x100mm{sup 2} with 0.5 mm interval) to 87.5% (scanning of 200x200mm{sup 2} with 0.5 mm interval) less processing time, strengthening the claim for the research. This new concept to implement FPGA technology into the UPI system will act as a break-through technology for full-scale automatic inspection.

  14. Audiologist-patient communication profiles in hearing rehabilitation appointments.

    Science.gov (United States)

    Meyer, Carly; Barr, Caitlin; Khan, Asaduzzaman; Hickson, Louise

    2017-08-01

    To profile the communication between audiologists and patients in initial appointments on a biomedical-psychosocial continuum; and explore the associations between these profiles and 1) characteristics of the appointment and 2) patients' decisions to pursue hearing aids. Sixty-three initial hearing assessment appointments were filmed and audiologist-patient communication was coded using the Roter Interaction Analysis System. A hierarchical cluster analysis was conducted to profile audiologist-patient communication, after which regression modelling and Chi-squared analyses were conducted. Two distinct audiologist-patient communication profiles were identified during both the history taking phase (46=biopsychosocial profile, 15=psychosocial profile) and diagnosis and management planning phase (45=expanded biomedical profile, 11=narrowly biomedical profile). Longer appointments were significantly more likely to be associated with an expanded biomedical interaction during the diagnosis and management planning phase. No significant associations were found between audiologist-patient communication profile and patients' decisions to pursue hearing aids. Initial audiology consultations appear to remain clinician-centred. Three quarters of appointments began with a biopsychosocial interaction; however, 80% ended with an expanded biomedical interaction. Findings suggest that audiologists could consider modifying their communication in initial appointments to more holistically address the needs of patients. Copyright © 2017 Elsevier B.V. All rights reserved.

  15. Development of field programmable gate array-based reactor trip functions using systems engineering approach

    Energy Technology Data Exchange (ETDEWEB)

    Jung, Jae Cheon; Ahmed, Ibrahim [Nuclear Power Plant Engineering, KEPCO International Nuclear Graduate School, Ulsan (Korea, Republic of)

    2016-08-15

    Design engineering process for field programmable gate array (FPGA)-based reactor trip functions are developed in this work. The process discussed in this work is based on the systems engineering approach. The overall design process is effectively implemented by combining with design and implementation processes. It transforms its overall development process from traditional V-model to Y-model. This approach gives the benefit of concurrent engineering of design work with software implementation. As a result, it reduces development time and effort. The design engineering process consisted of five activities, which are performed and discussed: needs/systems analysis; requirement analysis; functional analysis; design synthesis; and design verification and validation. Those activities are used to develop FPGA-based reactor bistable trip functions that trigger reactor trip when the process input value exceeds the setpoint. To implement design synthesis effectively, a model-based design technique is implied. The finite-state machine with data path structural modeling technique together with very high speed integrated circuit hardware description language and the Aldec Active-HDL tool are used to design, model, and verify the reactor bistable trip functions for nuclear power plants.

  16. Field Programmable Gate Array Control of Power Systems in Graduate Student Laboratories

    National Research Council Canada - National Science Library

    O'Connor, Joseph E

    2008-01-01

    ...) continuously develops new design and education resources for students. One area of focus for students in the Power Electronics curriculum track is the development of a design center that explores Field Programmable Gate Array (FPGA...

  17. Evaluation of the Usefulness of the Respiratory Guidance System in the Respiratory Gating Radiation Therapy

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Yeong Cheol; Kim, Sun Myung; Do, Gyeong Min; Park, Geun Yong; Kim, Gun Oh; Kim, Young Bum [Dept. of Radiation Oncology, Guro Hospital, Korea Univeristy, Seoul (Korea, Republic of)

    2012-09-15

    The respiration is one of the most important factors in respiratory gating radiation therapy (RGRT). We have developed an unique respiratory guidance system using an audio-visual system in order to support and stabilize individual patient's respiration and evaluated the usefulness of this system. Seven patients received the RGRT at our clinic from June 2011 to April 2012. After breathing exercise standard deviations by the superficial contents of respiratory cycles and functions, and analyzed them to examine changes in their breathing before and with the audio-visual system, we measured their spontaneous respiration and their respiration with the audio-visual system respectively. With the measured data, we yielded after the therapy. The PTP (peak to peak) of the standard deviations of the free breathing, the audio guidance system, and the respiratory guidance system were 0.343, 0.148, and 0.078 respectively. The respiratory cycles were 0.645, 0.345, and 0.171 respectively and the superficial contents of the respiratory functions were 2.591, 1.008, and 0.877 respectively. The average values of the differences in the standard deviations among the whole patients at the CT room and therapy room were 0.425 for the PTP, 1.566 for the respiratory cycles, and 3.671 for the respiratory superficial contents. As for the standard deviations before and after the application of the PTP respiratory guidance system, that of the PTP was 0.265, that of the respiratory cycles was 0.474, and that of the respiratory superficial contents. The results of t-test of the values before and after free breathing and the audio-visual guidance system showed that the P-value of the PTP was 0.035, that of the cycles 0.009, and that of the respiratory superficial contents 0.010. The respiratory control could be one of the most important factors in the RGRT which determines the success or failure of a treatment. We were able to get more stable breathing with the audio-visual respiratory

  18. Evaluation of an infrared camera and X-ray system using implanted fiducials in patients with lung tumors for gated radiation therapy

    International Nuclear Information System (INIS)

    Willoughby, Twyla R.; Forbes, Alan R.; Buchholz, Daniel; Langen, Katja M.; Wagner, Thomas H.; Zeidan, Omar A.; Kupelian, Patrick A.; Meeks, Sanford L.

    2006-01-01

    Purpose: To report on the initial clinical use of a commercially available system to deliver gated treatment using implanted fiducials, in-room kV X-rays, and an infrared camera tracking system. Methods and Materials: ExacTrac Adaptive Gating from BrainLab is a localization system using infrared cameras and X-rays. Gating signals are the patient's breathing pattern obtained from infrared reflectors on the patient. kV X-rays of an implanted fiducial are synchronized to the breathing pattern. After localization and shift of the patient to isocenter, the breathing pattern is used to gate Radiation. Feasibility tests included localization accuracy, radiation output constancy, and dose distributions with gating. Clinical experience is reported on treatment of patients with small lung lesions. Results: Localization accuracy of a moving target with gating was 1.7 mm. Dose constancy measurements showed insignificant change in output with gating. Improvements of dose distributions on moving targets improved with gating. Eleven patients with lung lesions were implanted with 20 mm x 0.7 mm gold coil (Visicoil). The implanted fiducial was used to localize and treat the patients with gating. Treatment planning and repeat computed tomographic scans showed that the change in center of gross target volume (GTV) to implanted marker averaged 2.47 mm due in part to asymmetric tumor shrinkage. Conclusion: ExacTrac Adaptive Gating has been used to treat lung lesions. Initial system evaluation verified its accuracy and usability. Implanted fiducials are visible in X-rays and did not migrate

  19. SU-F-J-121: Dosimetric Evaluation of Active Breathing Coordinator-Response Gating System Linked to Linear Accelerator in Volumetric Modulated Arc Therapy

    Energy Technology Data Exchange (ETDEWEB)

    Lee, S; Zheng, Y; Albani, D; Colussi, V; Dorth, J; Sohn, J [Case Western University, Cleveland, OH (United States)

    2016-06-15

    Purpose: To reduce internal target volume (ITV), respiratory management is a must in imaging and treatment for lung, liver, and breast cancers. We investigated the dosimetric accuracy of VMAT treatment delivery with a Response™ gating system linked to linear accelerator. Methods: The Response™ gating module designed to directly control radiation beam by breath-holding with a ABC system (Elekta AB, Stockholm, Sweden) was tested for VMAT treatments. Seven VMAT plans including three conventional and four stereotactic body radiotherapy (SBRT) cases were evaluated. Each plan was composed of two or four arcs of 6MV radiation beam with prescribed dose ranged from 1.8 to 9 Gy per fraction. Each plan was delivered continuously without gating and delivered with multiple interruptions by the ResponseTM gating module with a 20 or 30 second breath-holding period. MapCheck2 and Gafchromic EBT3 films sandwiched in MapPHAN were used to measure the delivered dose with and without gating. Films were scanned on a flatbed color scanner, and red channel was extracted for film dosimetry. Gamma analysis was performed to analyze the dosimetrical accuracy of the radiation delivery with gating. Results: The measured doses with gating remarkably agree with the planned dose distributions in the results of gamma index passing rate (within 20% isodose; >98% for 3%/3mm and >92% for 2%/2mm in MapCheck2, and >91% for 3%/3mm criteria in EBT3 film except one case which was for large target and highly modulated). No significant difference (student t-test: p-value < 0.0005) was shown between the doses delivered with and without gating. There was no indication of radiation gap or overlapping during deliver interruption in film dosimetry. Conclusion: The Response™ gating system can be safely used during VMAT treatment. The accurate performance of the gating system linked to ABC can contribute to ITV reduction for SBRT using VMAT.

  20. Outpatient Appointment Scheduling with Variable Interappointment Times

    Directory of Open Access Journals (Sweden)

    Song Foh Chew

    2011-01-01

    Full Text Available Healthcare currently consumes 17% of the U.S. Gross Domestic Product and is expected to reach 20% within the coming decade. Confronted with such high costs, sharp demand, and limited capacity, many hospitals now are vying for shorter lengths of stay and are transferring services from inpatient to outpatient facilities. This paper seeks to develop a methodology for constructing effective outpatient appointment scheduling systems. The objective of these appointment systems is to minimize the average total cost function describing total costs incurred by patient waiting and by staff idle time and overtime. In the paper, we will establish that the average total cost function exhibits a unimodal curve. The lowest point of the curve essentially means the lowest average total cost. We will next develop a simulation-based heuristic algorithm for finding an outpatient schedule near the lowest point. In the paper, we present numerical examples using the heuristic based upon a set of predetermined unit costs. Specifically, we find the near optimal interappointment times for schedules, where there are two and three patients in each block, respectively. The current work does not consider possible no shows and walk-ins. Future work will undertake these issues.

  1. Single Event Test Methodologies and System Error Rate Analysis for Triple Modular Redundant Field Programmable Gate Arrays

    Science.gov (United States)

    Allen, Gregory; Edmonds, Larry D.; Swift, Gary; Carmichael, Carl; Tseng, Chen Wei; Heldt, Kevin; Anderson, Scott Arlo; Coe, Michael

    2010-01-01

    We present a test methodology for estimating system error rates of Field Programmable Gate Arrays (FPGAs) mitigated with Triple Modular Redundancy (TMR). The test methodology is founded in a mathematical model, which is also presented. Accelerator data from 90 nm Xilins Military/Aerospace grade FPGA are shown to fit the model. Fault injection (FI) results are discussed and related to the test data. Design implementation and the corresponding impact of multiple bit upset (MBU) are also discussed.

  2. Azobenzene polyesters used as gate-like scaffolds in nanoscopic hybrid systems.

    Science.gov (United States)

    Bernardos, Andrea; Mondragón, Laura; Javakhishvili, Irakli; Mas, Núria; de la Torre, Cristina; Martínez-Máñez, Ramón; Sancenón, Félix; Barat, José M; Hvilsted, Søren; Orzaez, Mar; Pérez-Payá, Enríque; Amorós, Pedro

    2012-10-08

    The synthesis and characterisation of new capped silica mesoporous nanoparticles for on-command delivery applications is reported. Functional capped hybrid systems consist of MCM-41 nanoparticles functionalised on the external surface with polyesters bearing azobenzene derivatives and rhodamine B inside the mesopores. Two solid materials, Rh-PAzo8-S and Rh-PAzo6-S, containing two closely related polymers, PAzo8 and PAzo6, in the pore outlets have been prepared. Materials Rh-PAzo8-S and Rh-PAzo6-S showed an almost zero release in water due to steric hindrance imposed by the presence of anchored bulky polyesters, whereas a large delivery of the cargo was observed in the presence of an esterase enzyme due to the progressive hydrolysis of polyester chains. Moreover, nanoparticles Rh-PAzo8-S and Rh-PAzo6-S were used to study the controlled release of the dye in intracellular media. Nanoparticles were not toxic for HeLa cells and endocytosis-mediated cell internalisation was confirmed by confocal microscopy. Furthermore, the possible use of capped materials as a drug-delivery system was demonstrated by the preparation of a new mesoporous silica nanoparticle functionalised with PAzo6 and loaded with the cytotoxic drug camptothecin (CPT-PAzo6-S). Following cell internalisation and lysosome resident enzyme-dependent gate opening, CPT-PAzo6-S induced CPT-dependent cell death in HeLa cells. Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  3. Funnel-and-gate remediation systems augmented with passive filter wells.

    Science.gov (United States)

    Hudak, Paul F

    2010-09-01

    The objective of this study was to evaluate the ability of funnel-and-gate structures augmented with passive wells containing filter cartridges to capture contaminated groundwater in hypothetical, homogeneous and heterogeneous, unconfined aquifers. Perpendicular to groundwater flow, linear structures were 15 m wide, 1 m thick, and keyed into the base of the aquifer. Gates occupied 4 m of the total width of each simulated structure; one gate was 5 m from a contaminant plume's leading tip, while others occupied cross-gradient margins of the plume. Results suggest a modest reduction in remediation timeframes, up to 425 d per well added in these simulations; however, incremental benefits are highly variable and case specific.

  4. Simulations of interference effects in gated two-dimensional ballistic electron systems

    DEFF Research Database (Denmark)

    Jauho, Antti-Pekka; Pichugin, K.N.; Sadreev, A.F.

    1999-01-01

    of the actual sample geometry, including a Poison equation-based determination of the potential due to the gate. The conductance is determined with the multiprobe Landauer-Buttiker formula, and in general we find conductance vs gate voltage characteristics, which closely resemble the experimental traces....... A detailed examination based on quantum-mechanical streamlines suggests that the simple one-dimensional semiclassical model often used to describe the experiments has only a limited range of validity, and that certain ''unexpected" periodicities should not be assigned any particular significance, they arise...

  5. Design of a scanning gate microscope for mesoscopic electron systems in a cryogen-free dilution refrigerator.

    Science.gov (United States)

    Pelliccione, M; Sciambi, A; Bartel, J; Keller, A J; Goldhaber-Gordon, D

    2013-03-01

    We report on our design of a scanning gate microscope housed in a cryogen-free dilution refrigerator with a base temperature of 15 mK. The recent increase in efficiency of pulse tube cryocoolers has made cryogen-free systems popular in recent years. However, this new style of cryostat presents challenges for performing scanning probe measurements, mainly as a result of the vibrations introduced by the cryocooler. We demonstrate scanning with root-mean-square vibrations of 0.8 nm at 3 K and 2.1 nm at 15 mK in a 1 kHz bandwidth with our design. Using Coulomb blockade thermometry on a GaAs/AlGaAs gate-defined quantum dot, we demonstrate an electron temperature of 45 mK.

  6. Solution-gated graphene field effect transistors integrated in microfluidic systems and used for flow velocity detection.

    Science.gov (United States)

    He, Rong Xiang; Lin, Peng; Liu, Zhi Ke; Zhu, Hong Wei; Zhao, Xing Zhong; Chan, Helen L W; Yan, Feng

    2012-03-14

    Solution-gated graphene field effect transistors (SGGT) were integrated in microfluidic systems. The transfer characteristics of a SGGT with an Ag/AgCl gate electrode shifted horizontally with the change of the ionic concentration of KCl solution in the microchannel and the relationship can be fitted with the Nernst equation, which was attributed to the change of the potential drop at the Ag/AgCl electrode. Therefore the gate electrode is one important factor for the ion sensitive property of the SGGT. Then SGGTs were used as flow velocity sensors, which were based on measuring the streaming potentials in microfluidic channels. A linear relationship between the shift of the transfer curve of the SGGT and the flow velocity was obtained, indicating that the SGGT is a promising transducer for measuring flow velocity in a microchip. Since the streaming potential is influenced by the three physical quantities, including the flow velocity, the ionic strength of the fluid and the zeta potential of the substrate, the device can be used for sensing any one of the three quantities when the other two were known. It is noteworthy that SGGTs have been used for various types of chemical and biological sensors. Array of the devices integrated in multichannel microchips are expected to find many important applications in the lab-on-a-chip systems in the future. © 2012 American Chemical Society

  7. Modelling of coulometric sensor-actuator systems based on ISFETs with a porous actuator covering the gate

    OpenAIRE

    Luo, J.; Luo, J.; Olthuis, Wouter; Bergveld, Piet; Bos, M.; van der Linden, W.E.

    1993-01-01

    The ion-selective field effect transistor (ISFET)-based coulometric sensor¿actuator systems have found applications in acid¿base titration and in the construction of a low-drift carbon dioxide and a pH-static enzyme sensor. In this paper a brief review is given of the previously developed ISFET-based sensor¿actuator systems and the newly proposed system which employs a porous nobel metal as the actuator deposited at a short distance over the gate. The advantages and disadvantages of the diffe...

  8. The human respiratory gate

    Science.gov (United States)

    Eckberg, Dwain L.

    2003-01-01

    Respiratory activity phasically alters membrane potentials of preganglionic vagal and sympathetic motoneurones and continuously modulates their responsiveness to stimulatory inputs. The most obvious manifestation of this 'respiratory gating' is respiratory sinus arrhythmia, the rhythmic fluctuations of electrocardiographic R-R intervals observed in healthy resting humans. Phasic autonomic motoneurone firing, reflecting the throughput of the system, depends importantly on the intensity of stimulatory inputs, such that when levels of stimulation are low (as with high arterial pressure and sympathetic activity, or low arterial pressure and vagal activity), respiratory fluctuations of sympathetic or vagal firing are also low. The respiratory gate has a finite capacity, and high levels of stimulation override the ability of respiration to gate autonomic responsiveness. Autonomic throughput also depends importantly on other factors, including especially, the frequency of breathing, the rate at which the gate opens and closes. Respiratory sinus arrhythmia is small at rapid, and large at slow breathing rates. The strong correlation between systolic pressure and R-R intervals at respiratory frequencies reflects the influence of respiration on these two measures, rather than arterial baroreflex physiology. A wide range of evidence suggests that respiratory activity gates the timing of autonomic motoneurone firing, but does not influence its tonic level. I propose that the most enduring significance of respiratory gating is its use as a precisely controlled experimental tool to tease out and better understand otherwise inaccessible human autonomic neurophysiological mechanisms.

  9. Optimization and evaluation of multiple gating beam delivery in a synchrotron-based proton beam scanning system using a real-time imaging technique.

    Science.gov (United States)

    Yamada, Takahiro; Miyamoto, Naoki; Matsuura, Taeko; Takao, Seishin; Fujii, Yusuke; Matsuzaki, Yuka; Koyano, Hidenori; Umezawa, Masumi; Nihongi, Hideaki; Shimizu, Shinichi; Shirato, Hiroki; Umegaki, Kikuo

    2016-07-01

    To find the optimum parameter of a new beam control function installed in a synchrotron-based proton therapy system. A function enabling multiple gated irradiation in the flat top phase has been installed in a real-time-image gated proton beam therapy (RGPT) system. This function is realized by a waiting timer that monitors the elapsed time from the last gate-off signal in the flat top phase. The gated irradiation efficiency depends on the timer value, Tw. To find the optimum Tw value, gated irradiation efficiency was evaluated for each configurable Tw value. 271 gate signal data sets from 58 patients were used for the simulation. The highest mean efficiency 0.52 was obtained in TW=0.2s. The irradiation efficiency was approximately 21% higher than at TW=0s, which corresponds to ordinary synchrotron operation. The irradiation efficiency was improved in 154 (57%) of the 271 cases. The irradiation efficiency was reduced in 117 cases because the TW value was insufficient or the function introduced an unutilized wait time for the next gate-on signal in the flat top phase. In the actual treatment of a patient with a hepatic tumor at Tw=0.2s, 4.48GyE irradiation was completed within 250s. In contrast, the treatment time of ordinary synchrotron operation was estimated to be 420s. The results suggest that the multiple gated-irradiation function has potential to improve the gated irradiation efficiency and to reduce the treatment time. Copyright © 2016 Associazione Italiana di Fisica Medica. Published by Elsevier Ltd. All rights reserved.

  10. Storm that rocks the boat: the systemic impact of gated communities on urban sustainability

    CSIR Research Space (South Africa)

    Landman, K

    2007-01-01

    Full Text Available requirement for this is the ability of all to live a safe, healthy and productive life in harmony with nature and local cultural and spiritual values (Du Plessis and Landman 2002). Sustainability is therefore concerned with reconciling the long...) and local economic growth (in municipalities). In addition to these drivers are the social and technical factors that influence the growth of gated communities in South African cities, namely territoriality and ownership, sense of community, social values...

  11. The validity of the RWA and gate operation speedup by violating RWA in resonant-driven qubit systems

    Science.gov (United States)

    Song, Yang

    The rotating wave approximation (RWA) is ubiquitously used in understanding (quasi)resonant driven systems and designing pulses for state evolution. Following the practice in atomic and NMR physics, a wide range of semiconducting qubit systems are driven resonantly to manipulate the qubit, including single-spin/resonant exchange (RX)/various singlet-triplet(ST)/spin-charge hybrid qubits. The purpose of this talk is twofold: (I) Examine the validity of RWA in different qubit systems and analyze the error in terms of quantum computation; (II) Present faster gate operations by going into RWA-invalid regime for resonant-driven qubits (esp. for ST and RX types). We measure the RWA-induced infidelity and discuss it in view of the fault-tolerant error correction threshold and operation speeds. Applying the analytical extension (two orders higher than RWA) greatly reduces the infidelity, in the regime where the RWA is attempted to be used. Moreover, we show that the resonant-driven system is not limited by the Rabi-like weak coupling limit and the associated slow gate speed, much smaller than the level splitting (e.g., the small Zeeman energy gradient in ST qubits). We demonstrate the universal one qubit gates for driving strength up to a few level splitting, achieving fast control with only simple sinusoidal pulses. We also solve for the `shifted sinusoidal' pulses needed for ST qubits where the exchange coupling cannot change signs. In collaboration with Xin Wang, Jason Kestner and Sankar Das Sarma, and supported by LPS-MPO-CMTC and IARPA-MQCO.

  12. Wedge gate valves selecting essentials in pipeline systems designing based on permissible operation parameters

    Science.gov (United States)

    Zakirnichnaya, M. M.; Kulsharipov, I. M.

    2017-10-01

    Wedge gate valves are widely used at the fuel and energy complex enterprises. The pipeline valves manufacturers indicate the safe operation resource according to the current regulatory and technical documentation. In this case, the resource value of the valve body strength calculation results is taken into consideration as the main structural part. However, it was determined that the wedge gate valves fail before the assigned resource due to the occurrence of conditions under which the wedge breaks in the hooks and, accordingly, the sealing integrity is not ensured. In this regard, it became necessary to assess the conditions under which the resource should be assigned not only to the valve body, but also to take into account the wedge durability. For this purpose, wedge resource calculations were made using the example of ZKL2 250-25 and ZKL2 300-25 valves using the ABAQUS software package FE-SAFE module under the technological parameters influence on the basis of their stressstrain state calculation results. Operating conditions, under which the wedge resource value is lower than the one set by the manufacturer, were determined. A technique for limiting the operating parameters for ensuring the wedge durability during the wedge gate valve assigned resource is proposed.

  13. Competence developmental needs of newly appointed nurse ...

    African Journals Online (AJOL)

    Competence developmental needs of newly appointed nurse educators during the mentoring process. E Seekoe ... The results indicated that the newly appointed nurse educator's lacks mentoring in areas such as teaching, research, community engagement, interpersonal relations and work ethics. Mentoring seemed to be ...

  14. 48 CFR 1401.603-3 - Appointment.

    Science.gov (United States)

    2010-10-01

    ... Responsibilities 1401.603-3 Appointment. Purchase card holders may be appointed in writing or in accordance with the bureau/office procedures within the constraints of DOI Integrated Charge Card Program Policy Manual located at http://www.doi.gov/pam/chargecard. Additional guidance is available in the GSA Smart...

  15. 5 CFR 2.2 - Appointments.

    Science.gov (United States)

    2010-01-01

    ... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Appointments. 2.2 Section 2.2 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE RULES APPOINTMENT THROUGH THE COMPETITIVE... career service to necessary fluctuations in Federal employment, and provide an equitable and orderly...

  16. Development of patient-controlled respiratory gating system based on visual guidance for magnetic-resonance image-guided radiation therapy.

    Science.gov (United States)

    Kim, Jung-In; Lee, Hanyoung; Wu, Hong-Gyun; Chie, Eui Kyu; Kang, Hyun-Cheol; Park, Jong Min

    2017-09-01

    The aim of this study is to develop a visual guidance patient-controlled (VG-PC) respiratory gating system for respiratory-gated magnetic-resonance image-guided radiation therapy (MR-IGRT) and to evaluate the performance of the developed system. The near-real-time cine planar MR image of a patient acquired during treatment was transmitted to a beam projector in the treatment room through an optical fiber cable. The beam projector projected the cine MR images inside the bore of the ViewRay system in order to be visible to a patient during treatment. With this visual information, patients voluntarily controlled their respiration to put the target volume into the gating boundary (gating window). The effect of the presence of the beam projector in the treatment room on the image quality of the MRI was investigated by evaluating the signal-to-noise ratio (SNR), uniformity, low-contrast detectability, high-contrast spatial resolution, and spatial integrity with the VG-PC gating system. To evaluate the performance of the developed system, we applied the VG-PC gating system to a total of seven patients; six patients received stereotactic ablative radiotherapy (SABR) and one patient received conventional fractionated radiation therapy. The projected cine MR images were visible even when the room light was on. No image data loss or additional time delay during delivery of image data were observed. Every indicator representing MRI quality, including SNR, uniformity, low-contrast detectability, high-contrast spatial resolution, and spatial integrity exhibited values higher than the tolerance levels of the manufacturer with the VG-PC gating system; therefore, the presence of the VG-PC gating system in the treatment room did not degrade the MR image quality. The average beam-off times due to respiratory gating with and without the VG-PC gating system were 830.3 ± 278.2 s and 1264.2 ± 302.1 s respectively (P = 0.005). Consequently, the total treatment times excluding

  17. SU-F-J-151: Evaluation of a Magnetic Resonance Image Gated Radiotherapy System Using a Motion Phantom and Radiochromic Film

    Energy Technology Data Exchange (ETDEWEB)

    Lamb, J; Ginn, J; O’Connell, D; Thomas, D; Agazaryan, N; Cao, M; Yang, Y; Low, D [UCLA, Los Angeles, CA (United States)

    2016-06-15

    Purpose: Magnetic resonance image (MRI) guided radiotherapy enables gating directly on target position for soft-tissue targets in the lung and abdomen. We present a dosimetric evaluation of a commercially-available FDA-approved MRI-guided radiotherapy system’s gating performance using a MRI-compatible respiratory motion phantom and radiochromic film. Methods: The MRI-compatible phantom was capable of one-dimensional motion. The phantom consisted of a target rod containing high-contrast target inserts which moved inside a body structure containing background contrast material. The target rod was equipped with a radiochromic film insert. Treatment plans were generated for a 3 cm diameter spherical target, and delivered to the phantom at rest and in motion with and without gating. Both sinusoidal and actual tumor trajectories (two free-breathing trajectories and one repeated-breath hold) were used. Gamma comparison at 5%/3mm was used to measure fidelity to the static target dose distribution. Results: Without gating, gamma pass rates were 24–47% depending on motion trajectory. Using our clinical standard of repeated breath holds and a gating window of 3 mm with 10% of the target allowed outside the gating boundary, the gamma pass rate was 99.6%. Relaxing the gating window to 5 mm resulted in gamma pass rate of 98.6% with repeated breath holds. For all motion trajectories gated with 3 mm margin and 10% allowed out, gamma pass rates were between 64–100% (mean:87.5%). For a 5 mm margin and 10% allowed out, gamma pass rates were between 57–98% (mean: 82.49%), significantly lower than for 3 mm by paired t-test (p=0.01). Conclusion: We validated the performance of respiratory gating based on real-time cine MRI images with the only FDA-approved MRI-guided radiotherapy system. Our results suggest that repeated breath hold gating should be used when possible for best accuracy. A 3 mm gating margin is statistically significantly more accurate than a 5 mm gating margin.

  18. SU-E-T-266: Development of Evaluation System of Optimal Synchrotron Controlling Parameter for Spot Scanning Proton Therapy with Multiple Gate Irradiations in One Operation Cycle

    International Nuclear Information System (INIS)

    Yamada, T; Fujii, Y; Miyamoto, N; Matsuura, T; Takao, S; Matsuzaki, Y; Koyano, H; Shirato, H; Nihongi, H; Umezawa, M; Matsuda, K; Umegaki, K

    2015-01-01

    Purpose: We have developed a gated spot scanning proton beam therapy system with real-time tumor-tracking. This system has the ability of multiple-gated irradiation in a single synchrotron operation cycle controlling the wait-time for consecutive gate signals during a flat-top phase so that the decrease in irradiation efficiency induced by irregular variation of gate signal is reduced. Our previous studies have shown that a 200 ms wait-time is appropriate to increase the average irradiation efficiency, but the optimal wait-time can vary patient by patient and day by day. In this research, we have developed an evaluation system of the optimal wait-time in each irradiation based on the log data of the real-time-image gated proton beam therapy (RGPT) system. Methods: The developed system consists of logger for operation of RGPT system and software for evaluation of optimal wait-time. The logger records timing of gate on/off, timing and the dose of delivered beam spots, beam energy and timing of X-ray irradiation. The evaluation software calculates irradiation time in the case of different wait-time by simulating the multiple-gated irradiation operation using several timing information. Actual data preserved in the log data are used for gate on and off time, spot irradiation time, and time moving to the next spot. Design values are used for the acceleration and deceleration times. We applied this system to a patient treated with the RGPT system. Results: The evaluation system found the optimal wait-time of 390 ms that reduced the irradiation time by about 10 %. The irradiation time with actual wait-time used in treatment was reproduced with accuracy of 0.2 ms. Conclusion: For spot scanning proton therapy system with multiple-gated irradiation in one synchrotron operation cycle, an evaluation system of the optimal wait-time in each irradiation based on log data has been developed. Funding Support: Japan Society for the Promotion of Science (JSPS) through the FIRST

  19. A 65-kV insulated gate bipolar transistor switch applied in damped AC voltages partial discharge detection system.

    Science.gov (United States)

    Jiang, J; Ma, G M; Luo, D P; Li, C R; Li, Q M; Wang, W

    2014-02-01

    Damped AC voltages detection system (DAC) is a productive way to detect the faults in power cables. To solve the problems of large volume, complicated structure and electromagnetic interference in existing switches, this paper developed a compact solid state switch based on electromagnetic trigger, which is suitable for DAC test system. Synchronous electromagnetic trigger of 32 Insulated Gate Bipolar Transistors (IGBTs) in series was realized by the topological structure of single line based on pulse width modulation control technology. In this way, external extension was easily achieved. Electromagnetic trigger and resistor-capacitor-diode snubber circuit were optimized to reduce the switch turn-on time and circular layout. Epoxy encapsulating was chosen to enhance the level of partial discharge initial voltage (PDIV). The combination of synchronous trigger and power supply is proposed to reduce the switch volume. Moreover, we have overcome the drawback of the electromagnetic interference and improved the detection sensitivity of DAC by using capacitor storage energy to maintain IGBT gate driving voltage. The experimental results demonstrated that the solid-state switch, with compact size, whose turn-on time was less than 400 ns and PDIV was more than 65 kV, was able to meet the actual demands of 35 kV DAC test system.

  20. Penn State DOE GATE Program

    Energy Technology Data Exchange (ETDEWEB)

    Anstrom, Joel

    2012-08-31

    The Graduate Automotive Technology Education (GATE) Program at The Pennsylvania State University (Penn State) was established in October 1998 pursuant to an award from the U.S. Department of Energy (U.S. DOE). The focus area of the Penn State GATE Program is advanced energy storage systems for electric and hybrid vehicles.

  1. Factors Associated With Missed and Cancelled Colonoscopy Appointments at Veterans Health Administration Facilities.

    Science.gov (United States)

    Partin, Melissa R; Gravely, Amy; Gellad, Ziad F; Nugent, Sean; Burgess, James F; Shaukat, Aasma; Nelson, David B

    2016-02-01

    Cancelled and missed colonoscopy appointments waste resources, increase colonoscopy delays, and can adversely affect patient outcomes. We examined individual and organizational factors associated with missed and cancelled colonoscopy appointments in Veteran Health Administration facilities. From 69 facilities meeting inclusion criteria, we identified 27,994 patients with colonoscopy appointments scheduled for follow-up, on the basis of positive fecal occult blood test results, between August 16, 2009 and September 30, 2011. We identified factors associated with colonoscopy appointment status (completed, cancelled, or missed) by using hierarchical multinomial regression. Individual factors examined included age, race, sex, marital status, residence, drive time to nearest specialty care facility, limited life expectancy, comorbidities, colonoscopy in the past decade, referring facility type, referral month, and appointment lead time. Organizational factors included facility region, complexity, appointment reminders, scheduling, and prep education practices. Missed appointments were associated with limited life expectancy (odds ratio [OR], 2.74; P = .0004), no personal history of polyps (OR, 2.74; P < .0001), high facility complexity (OR, 2.69; P = .007), dual diagnosis of psychiatric disorders and substance abuse (OR, 1.82; P < .0001), and opt-out scheduling (OR, 1.57; P = .02). Cancelled appointments were associated with age (OR, 1.61; P = .0005 for 85 years or older and OR, 1.44; P < .0001 for 65-84 years old), no history of polyps (OR, 1.51; P < .0001), and opt-out scheduling (OR, 1.26; P = .04). Additional predictors of both outcomes included race, marital status, and lead time. Several factors within Veterans Health Administration clinic control can be targeted to reduce missed and cancelled colonoscopy appointments. Specifically, developing systems to minimize referrals for patients with limited life expectancy could reduce missed appointments, and use of opt

  2. Evaluation of the MEMS based portable respiratory training system with a tactile sensor for respiratory-gated radiotherapy

    Science.gov (United States)

    Moon, Sun Young; Yoon, Myonggeun; Chung, Mijoo; Chung, Weon Kuu; Kim, Dong Wook

    2017-10-01

    In respiratory-gated radiotherapy, it is important to maintain the regular respiratory cycles of patients. If patients undergo respiration training, their regular breathing pattern is affected. Therefore, we developed a respiratory training system based on a micro electromechanical system (MEMS) and evaluated the feasibility of the MEMS in radiotherapy. By comparing the measured signal before and after radiation exposure, we confirmed the effects of radiation. By evaluating the period of the electric signal emitted by a tactile sensor and its constancy, the performance of the tactile sensor was confirmed. Moreover, by comparing the delay between the motion of the MEMS and the electric signal from the tactile sensor, we confirmed the reaction time of the tactile sensor. The results showed that a baseline shift occurred for an accumulated dose of 400 Gy in the sensor, and both the amplitude and period changed. The period of the signal released by the tactile sensor was 5.39 and its standard deviation was 0.06. Considering the errors from the motion phantom, a standard deviation of 0.06 was desirable. The delay time was within 0.5 s and not distinguishable by a patient. We confirmed the performance of the MEMS and concluded that MEMS could be applied to patients for respiratory-gated radiotherapy.

  3. Pathways to care and psychological problems of general practice patients in a "gate keeper" and an "open access" health care system - A comparison of Germany and the Netherlands

    NARCIS (Netherlands)

    Linden, M; Gothe, H; Ormel, J

    2003-01-01

    Background The comparison of different health care systems is one way to give empirical evidence to health care reform and policy. The differences between health care systems in which general practitioners serve as gate keepers in comparison to systems in which patients are free to contact every

  4. Spin gating electrical current

    Science.gov (United States)

    Ciccarelli, C.; Zârbo, L. P.; Irvine, A. C.; Campion, R. P.; Gallagher, B. L.; Wunderlich, J.; Jungwirth, T.; Ferguson, A. J.

    2012-09-01

    The level of the chemical potential is a fundamental parameter of the electronic structure of a physical system, which consequently plays an important role in defining the properties of active electrical devices. We directly measure the chemical potential shift in the relativistic band structure of the ferromagnetic semiconductor (Ga,Mn)As, controlled by changes in its magnetic order parameter. Our device comprises a non-magnetic aluminum single electron channel capacitively coupled to the (Ga,Mn)As gate electrode. The chemical potential shifts of the gate are directly read out from the shifts in the Coulomb blockade oscillations of the single electron transistor. The experiments introduce a concept of spin gating electrical current. In our spin transistor spin manipulation is completely removed from the electrical current carrying channel.

  5. Gate control of the spin mobility through the modification of the spin-orbit interaction in two-dimensional systems

    Science.gov (United States)

    Luengo-Kovac, M.; Moraes, F. C. D.; Ferreira, G. J.; Ribeiro, A. S. L.; Gusev, G. M.; Bakarov, A. K.; Sih, V.; Hernandez, F. G. G.

    2017-06-01

    Spin drag measurements were performed in a two-dimensional electron system set close to the crossed spin helix regime and coupled by strong intersubband scattering. In a sample with an uncommon combination of long spin lifetime and high charge mobility, the drift transport allows us to determine the spin-orbit field and the spin mobility anisotropies. We used a random walk model to describe the system dynamics and found excellent agreement for the Rashba and Dresselhaus couplings. The proposed two-subband system displays a large tuning lever arm for the Rashba constant with gate voltage, which provides a new path towards a spin transistor. Furthermore, the data show large spin mobility controlled by the spin-orbit constants setting the field along the direction perpendicular to the drift velocity. This work directly reveals the resistance experienced in the transport of a spin-polarized packet as a function of the strength of anisotropic spin-orbit fields.

  6. Selection and evaluation of an ultra high vacuum gate valve for Isabelle beam line vacuum system

    International Nuclear Information System (INIS)

    Foerster, C.L.; McCafferty, D.

    1980-01-01

    A minimum of eighty-four (84) Ultra High Vacuum Gate Valves will be utilized in ISABELLE to protect proton beam lines from catastrophic vacuum failure and to provide sector isolation for maintenance requirements. The valve to be selected must function at less than 1 x 10 -11 Torr pressure and be bakeable to 300 0 C in its open or closed position. In the open position, the valve must have an RF shield to make the beam line walls appear continuous. Several proposed designs were built and evaluated. The evaluation consisted mainly of leak testing, life tests, thermal cycling, mass spectrometer analysis, and 10 -12 Torr operation. Problems with initial design and fabrication were resolved. Special requirements for design and construction were developed. This paper describes the tests on two final prototypes which appear to be the best candidates for ISABELLE operation

  7. Clock recovery PLL with gated PFD for NRZ ON-OFF Modulated Signals in a retinal implant system.

    Science.gov (United States)

    Brendler, Christian; Aryan, Naser Pour; Rieger, Viola; Rothermel, Albrecht

    2013-01-01

    A Clock Recovery Phase Locked Loop with Gated Phase Frequency Detector (GPLL) for NRZ ON-OFF Modulated Signals with low data transmission rates for an inductively powered subretinal implant system is presented. Low data transmission rate leads to a long absence of inductive powering in the system when zeros are transmitted. Consequently there is no possibility to extract any clock in these pauses, thus the digital circuitry can not work any more. Compared to a commonly used PLL for clock extraction, no certain amount of data transitions is needed. This is achieved by having two operating modes. In one mode the GPLL tracks the HF input signal. In the other, the GPLL is an adjustable oscillator oscillating at the last used frequency. The proposed GPLL is fabricated and measured using a 350 nm High Voltage CMOS technology.

  8. Field programmable gate array-based real-time optical Doppler tomography system for in vivo imaging of cardiac dynamics in the chick embryo

    DEFF Research Database (Denmark)

    Thrane, Lars; Larsen, Henning Engelbrecht; Norozi, Kambiz

    2009-01-01

    We demonstrate a field programmable gate-array-based real-time optical Doppler tomography system. A complex-valued bandpass filter is used for the first time in optical coherence tomography signal processing to create the analytic signal. This method simplifies the filter design, and allows...... digital computer (CORDIC) algorithm, which is an efficient algorithm that maps well to the field programmable gate array. Flow phantom experiments, and the use of this system for in vivo imaging of cardiac dynamics in the chick embryo, are presented. We demonstrate the visualization of blood flow...

  9. Robust logic gates and realistic quantum computation

    International Nuclear Information System (INIS)

    Xiao Li; Jones, Jonathan A.

    2006-01-01

    The composite rotation approach has been used to develop a range of robust quantum logic gates, including single qubit gates and two qubit gates, which are resistant to systematic errors in their implementation. Single qubit gates based on the BB1 family of composite rotations have been experimentally demonstrated in a variety of systems, but little study has been made of their application in extended computations, and there has been no experimental study of the corresponding robust two qubit gates to date. Here we describe an application of robust gates to nuclear magnetic resonance studies of approximate quantum counting. We find that the BB1 family of robust gates is indeed useful, but that the related NB1, PB1, B4, and P4 families of tailored logic gates are less useful than initially expected

  10. Observation and characterization of flow in critical sections of a horizontal pressurized gating system using water models

    Directory of Open Access Journals (Sweden)

    Jaiganesh Venkataramani

    2013-07-01

    Full Text Available This work is concerned with the hydraulics and flow characterization in a pressurized, horizontal gating system with multiple ingates attached to a plate mold, using transparent water models. Runners with two different aspect ratios (w/h = 0.5 and 2 and four different types of ingates (rectangular, convergent, divergent and venturi were examined for their influence on flow behavior. Flow behavior was visualized using a high speed camera capable of capturing images up to 10,000 frames per second. Real time experimentation with a few runner – ingate combinations were carried out to validate the usefulness of water models in predicting the filling behavior. Comparison of the approaches provided useful insights into the filling behavior in critical sections of the flow passages as well as the utility of water models towards understanding of the filling behavior during real time casting.

  11. Danger: High Voltage—The Role of Voltage-Gated Calcium Channels in Central Nervous System Pathology

    Directory of Open Access Journals (Sweden)

    Andrea Schampel

    2017-11-01

    Full Text Available Voltage-gated calcium channels (VGCCs are widely distributed within the central nervous system (CNS and presumed to play an important role in the pathophysiology of a broad spectrum of CNS disorders including Alzheimer’s and Parkinson’s disease as well as multiple sclerosis. Several calcium channel blockers have been in clinical practice for many years so that their toxicity and side effects are well studied. However, these drugs are primarily used for the treatment of cardiovascular diseases and most if not all effects on brain functions are secondary to peripheral effects on blood pressure and circulation. While the use of calcium channel antagonists for the treatment of CNS diseases therefore still heavily depends on the development of novel strategies to specifically target different channels and channel subunits, this review is meant to provide an impulse to further emphasize the importance of future research towards this goal.

  12. Concurrent validity and test-retest reliability of a global positioning system (GPS) and timing gates to assess sprint performance variables.

    Science.gov (United States)

    Waldron, Mark; Worsfold, Paul; Twist, Craig; Lamb, Kevin

    2011-12-01

    There has been no previous investigation of the concurrent validity and reliability of the current 5 Hz global positioning system (GPS) to assess sprinting speed or the reliability of integrated GPS-accelerometer technology. In the present study, we wished to determine: (1) the concurrent validity and reliability of a GPS and timing gates to measure sprinting speed or distance, and (2) the reliability of proper accelerations recorded via GPS-accelerometer integration. Nineteen elite youth rugby league players performed two over-ground sprints and were simultaneously assessed using GPS and timing gates. The GPS measurements systematically underestimated both distance and timing gate speed. The GPS measurements were reliable for all variables of distance and speed (coefficient of variation [CV] = 1.62% to 2.3%), particularly peak speed (95% limits of agreement [LOA] = 0.00 ± 0.8 km · h(-1); CV = 0.78%). Timing gates were more reliable (CV = 1% to 1.54%) than equivalent GPS measurements. Accelerometer measurements were least reliable (CV = 4.69% to 5.16%), particularly for the frequency of proper accelerations (95% LOA = 1.00 ± 5.43; CV = 14.12%). Timing gates and GPS were found to reliably assess speed and distance, although the validity of the GPS remains questionable. The error found in accelerometer measurements indicates the limits of this device for detecting changes in performance.

  13. Super-resolution depth information from a short-wave infrared laser gated-viewing system by using correlated double sampling

    Science.gov (United States)

    Göhler, Benjamin; Lutzmann, Peter

    2017-10-01

    Primarily, a laser gated-viewing (GV) system provides range-gated 2D images without any range resolution within the range gate. By combining two GV images with slightly different gate positions, 3D information within a part of the range gate can be obtained. The depth resolution is higher (super-resolution) than the minimal gate shift step size in a tomographic sequence of the scene. For a state-of-the-art system with a typical frame rate of 20 Hz, the time difference between the two required GV images is 50 ms which may be too long in a dynamic scenario with moving objects. Therefore, we have applied this approach to the reset and signal level images of a new short-wave infrared (SWIR) GV camera whose read-out integrated circuit supports correlated double sampling (CDS) actually intended for the reduction of kTC noise (reset noise). These images are extracted from only one single laser pulse with a marginal time difference in between. The SWIR GV camera consists of 640 x 512 avalanche photodiodes based on mercury cadmium telluride with a pixel pitch of 15 μm. A Q-switched, flash lamp pumped solid-state laser with 1.57 μm wavelength (OPO), 52 mJ pulse energy after beam shaping, 7 ns pulse length and 20 Hz pulse repetition frequency is used for flash illumination. In this paper, the experimental set-up is described and the operating principle of CDS is explained. The method of deriving super-resolution depth information from a GV system by using CDS is introduced and optimized. Further, the range accuracy is estimated from measured image data.

  14. Management of the baseline shift using a new and simple method for respiratory-gated radiation therapy: Detectability and effectiveness of a flexible monitoring system

    International Nuclear Information System (INIS)

    Tachibana, Hidenobu; Kitamura, Nozomi; Ito, Yasushi; Kawai, Daisuke; Nakajima, Masaru; Tsuda, Akihisa; Shiizuka, Hisao

    2011-01-01

    Purpose: In respiratory-gated radiation therapy, a baseline shift decreases the accuracy of target coverage and organs at risk (OAR) sparing. The effectiveness of audio-feedback and audio-visual feedback in correcting the baseline shift in the breathing pattern of the patient has been demonstrated previously. However, the baseline shift derived from the intrafraction motion of the patient's body cannot be corrected by these methods. In the present study, the authors designed and developed a simple and flexible system. Methods: The system consisted of a web camera and a computer running our in-house software. The in-house software was adapted to template matching and also to no preimage processing. The system was capable of monitoring the baseline shift in the intrafraction motion of the patient's body. Another marker box was used to monitor the baseline shift due to the flexible setups required of a marker box for gated signals. The system accuracy was evaluated by employing a respiratory motion phantom and was found to be within AAPM Task Group 142 tolerance (positional accuracy <2 mm and temporal accuracy <100 ms) for respiratory-gated radiation therapy. Additionally, the effectiveness of this flexible and independent system in gated treatment was investigated in healthy volunteers, in terms of the results from the differences in the baseline shift detectable between the marker positions, which the authors evaluated statistically. Results: The movement of the marker on the sternum [1.599 ± 0.622 mm (1 SD)] was substantially decreased as compared with the abdomen [6.547 ± 0.962 mm (1 SD)]. Additionally, in all of the volunteers, the baseline shifts for the sternum [-0.136 ± 0.868 (2 SD)] were in better agreement with the nominal baseline shifts than was the case for the abdomen [-0.722 ± 1.56 mm (2 SD)]. The baseline shifts could be accurately measured and detected using the monitoring system, which could acquire the movement of the marker on the sternum. The

  15. Phosphodiesterase 3 and 5 and cyclic nucleotide-gated ion channel expression in rat trigeminovascular system

    DEFF Research Database (Denmark)

    Kruse, Lars S; Sandholdt, Nicolai T H; Gammeltoft, Steen

    2006-01-01

    may be associated with mutations in ion channels. The aim of the present study was to describe the expression of phosphodiesterase 3 (PDE3) and 5 (PDE5) and cyclic nucleotide-gated ion channels (CNG) in cerebral arteries, meninges, and the trigeminal ganglion. mRNA for PDE and CNG was determined...... in the rat middle cerebral artery, basilar artery, trigeminal ganglion, and dura mater using real-time PCR. PDE and CNG proteins were identified using Western blot. For comparison, rat aorta and mesenteric artery were analysed. PDE3A, PDE3B, and PDE5A mRNA were detected in all tissues examined except for PDE......3A mRNA in dura mater and the trigeminal ganglion. PDE5A and PDE3A protein expression was present in both cerebral and peripheral arteries, whereas PDE3B protein was present only in the cerebral arteries. The CNGA4 and B1 subunit mRNAs were detected in cerebral arteries and CNGA2 also...

  16. Improvement of the Reliability Graph with General Gates to Analyze the Reliability of Dynamic Systems That Have Various Operation Modes

    Directory of Open Access Journals (Sweden)

    Seung Ki Shin

    2016-04-01

    Full Text Available The safety of nuclear power plants is analyzed by a probabilistic risk assessment, and the fault tree analysis is the most widely used method for a risk assessment with the event tree analysis. One of the well-known disadvantages of the fault tree is that drawing a fault tree for a complex system is a very cumbersome task. Thus, several graphical modeling methods have been proposed for the convenient and intuitive modeling of complex systems. In this paper, the reliability graph with general gates (RGGG method, one of the intuitive graphical modeling methods based on Bayesian networks, is improved for the reliability analyses of dynamic systems that have various operation modes with time. A reliability matrix is proposed and it is explained how to utilize the reliability matrix in the RGGG for various cases of operation mode changes. The proposed RGGG with a reliability matrix provides a convenient and intuitive modeling of various operation modes of complex systems, and can also be utilized with dynamic nodes that analyze the failure sequences of subcomponents. The combinatorial use of a reliability matrix with dynamic nodes is illustrated through an application to a shutdown cooling system in a nuclear power plant.

  17. Buprenorphine shared medical appointments for the treatment of opioid dependence in a homeless clinic.

    Science.gov (United States)

    Doorley, Sara L; Ho, Cheryl J; Echeverria, Elizabeth; Preston, Charles; Ngo, Huy; Kamal, Ahmad; Cunningham, Chinazo O

    2017-01-01

    Opioid misuse and dependence are prevalent and rising problems in the United States. Treatment with buprenorphine is a successful treatment option for individuals with opioid dependence. This study describes and preliminarily evaluates a unique delivery system that provides buprenorphine treatment via a shared medical appointment. A retrospective medical record review on all 77 opioid-dependent patients referred for a buprenorphine shared medical appointment in a homeless clinic from 2010 to 2012. Most patients were currently homeless (61%), unemployed (92%), had an Axis I psychiatric diagnosis (81%), and had recent polysubstance use (53%). Of the 77 patients, 95% attended at least 1 shared medical appointment. Treatment retention at 12 and 24 weeks was 86% and 70%, respectively. In a patient population with complex social and mental health histories, buprenorphine treatment via a shared medical appointment had high retention rates. Findings can help guide the development of unique delivery systems to serve real-world complex patients with opioid dependence.

  18. Optimization of Gating System Design for Die Casting of Thin Magnesium Alloy-Based Multi-Cavity LCD Housings

    Science.gov (United States)

    Lee, B. D.; Baek, U. H.; Han, J. W.

    2012-09-01

    High-pressure die casting is the preferred process for manufacturing Mg-alloy components used for numerous applications. High-pressure die casting is suitable for mass production and has the advantage of also being suitable for accurately fashioning objects of complicated shapes. One disadvantage of high-speed die casting is the occurrence of defects such as shrinkage or air entrainment. Gating system design must be very effective in actual manufacturing facilities to avoid the occurrence of such defects. The objective of this study is to present a methodology for obtaining optimal designs of 4-cavity thin electronic component housings. The fluid behavior and amount of air entrainment caused by the overflows and air vent designs were analyzed using a computer fluid dynamics (CFD) simulator. The effectiveness of the proposed system was demonstrated through CFD simulations and experiments using an actual manufacturing process. Also, the effect of vacuum systems on the porosity and mechanical properties of the castings was studied. The volume of porosity in the casting was found to be significantly reduced using vacuum assistance during die casting. As a result, the tensile strength and the elongation of the die casting products are improved.

  19. SU-G-JeP1-08: Dual Modality Verification for Respiratory Gating Using New Real- Time Tumor Tracking Radiotherapy System

    Energy Technology Data Exchange (ETDEWEB)

    Shiinoki, T; Hanazawa, H; Shibuya, K [Yamaguchi University, Ube, Yamaguchi (Japan); Kawamura, S; Koike, M; Yuasa, Y; Uehara, T; Fujimoto, K [Yamaguchi University Hospital, Ube, Yamaguchi (Japan)

    2016-06-15

    Purpose: The respirato ry gating system combined the TrueBeam and a new real-time tumor-tracking radiotherapy system (RTRT) was installed. The RTRT system consists of two x-ray tubes and color image intensifiers. Using fluoroscopic images, the fiducial marker which was implanted near the tumor was tracked and was used as the internal surrogate for respiratory gating. The purposes of this study was to develop the verification technique of the respiratory gating with the new RTRT using cine electronic portal image device images (EPIDs) of TrueBeam and log files of the RTRT. Methods: A patient who underwent respiratory gated SBRT of the lung using the RTRT were enrolled in this study. For a patient, the log files of three-dimensional coordinate of fiducial marker used as an internal surrogate were acquired using the RTRT. Simultaneously, the cine EPIDs were acquired during respiratory gated radiotherapy. The data acquisition was performed for one field at five sessions during the course of SBRT. The residual motion errors were calculated using the log files (E{sub log}). The fiducial marker used as an internal surrogate into the cine EPIDs was automatically extracted by in-house software based on the template-matching algorithm. The differences between the the marker positions of cine EPIDs and digitally reconstructed radiograph were calculated (E{sub EPID}). Results: Marker detection on EPID using in-house software was influenced by low image contrast. For one field during the course of SBRT, the respiratory gating using the RTRT showed the mean ± S.D. of 95{sup th} percentile E{sub EPID} were 1.3 ± 0.3 mm,1.1 ± 0.5 mm,and those of E{sub log} were 1.5 ± 0.2 mm, 1.1 ± 0.2 mm in LR and SI directions, respectively. Conclusion: We have developed the verification method of respiratory gating combined TrueBeam and new real-time tumor-tracking radiotherapy system using EPIDs and log files.

  20. Appointment scheduling with unscheduled arrivals and reprioritization

    NARCIS (Netherlands)

    Borgman, Nardo J.; Vliegen, Ingrid M.H.; Boucherie, Richard J.; Hans, Erwin W.

    2017-01-01

    Inspired by the real life problem of a radiology department in a Dutch hospital, we study the problem of scheduling appointments, taking into account unscheduled arrivals and reprioritization. The radiology department offers CT diagnostics to both scheduled and unscheduled patients. Of these

  1. 7 CFR 1260.145 - Appointment.

    Science.gov (United States)

    2010-01-01

    ... Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE BEEF PROMOTION AND RESEARCH Beef Promotion and Research Order Cattlemen's Beef Promotion and Research Board § 1260.145 Appointment. (a) From...

  2. Maintenance Appointments in Railway Rolling Stock Rescheduling

    NARCIS (Netherlands)

    J.C. Wagenaar (Joris); L.G. Kroon (Leo); M.E. Schmidt (Marie)

    2016-01-01

    textabstractThis paper addresses the Rolling Stock Rescheduling Problem (RSRP), while taking maintenance appointments into account. After a disruption, the rolling stock of the disrupted passenger trains has to be rescheduled in order to restore a feasible rolling stock circulation. Usually, a

  3. Missed medical appointment among hypertensive and diabetic ...

    African Journals Online (AJOL)

    Purpose: To explore the reasons for missed medical appointment, patients' awareness on its consequences; and to find strategies to reduce it among the study population. Methods: This was a descriptive cross-sectional survey among 300 hypertensive and 200 diabetic outpatients assessing care at the University College ...

  4. 133 LEGISLATIVE APPROVAL OF EXECUTIVE APPOINTMENTS ...

    African Journals Online (AJOL)

    Fr. Ikenga

    that peace, order and good governance shall be promoted both at the Federal and State levels. Keywords: Executive appointments, Legislative approval, National Assembly, Constitutional duty. 1. Introduction. The National Assembly is the highest law making and representative body in Nigeria. It is the. Constitutional ...

  5. 5 CFR 330.1106 - Appointment.

    Science.gov (United States)

    2010-01-01

    ... Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS RECRUITMENT, SELECTION, AND PLACEMENT (GENERAL) Federal Employment Priority Consideration Program for Displaced Employees of the... under Public Law 105-274. For employees appointed before October 21, 1998, the conversion will be...

  6. Verification of respiratory-gated radiotherapy with new real-time tumour-tracking radiotherapy system using cine EPID images and a log file.

    Science.gov (United States)

    Shiinoki, Takehiro; Hanazawa, Hideki; Yuasa, Yuki; Fujimoto, Koya; Uehara, Takuya; Shibuya, Keiko

    2017-02-21

    A combined system comprising the TrueBeam linear accelerator and a new real-time tumour-tracking radiotherapy system, SyncTraX, was installed at our institution. The objectives of this study are to develop a method for the verification of respiratory-gated radiotherapy with SyncTraX using cine electronic portal image device (EPID) images and a log file and to verify this treatment in clinical cases. Respiratory-gated radiotherapy was performed using TrueBeam and the SyncTraX system. Cine EPID images and a log file were acquired for a phantom and three patients during the course of the treatment. Digitally reconstructed radiographs (DRRs) were created for each treatment beam using a planning CT set. The cine EPID images, log file, and DRRs were analysed using a developed software. For the phantom case, the accuracy of the proposed method was evaluated to verify the respiratory-gated radiotherapy. For the clinical cases, the intra- and inter-fractional variations of the fiducial marker used as an internal surrogate were calculated to evaluate the gating accuracy and set-up uncertainty in the superior-inferior (SI), anterior-posterior (AP), and left-right (LR) directions. The proposed method achieved high accuracy for the phantom verification. For the clinical cases, the intra- and inter-fractional variations of the fiducial marker were  ⩽3 mm and  ±3 mm in the SI, AP, and LR directions. We proposed a method for the verification of respiratory-gated radiotherapy with SyncTraX using cine EPID images and a log file and showed that this treatment is performed with high accuracy in clinical cases.

  7. Verification of respiratory-gated radiotherapy with new real-time tumour-tracking radiotherapy system using cine EPID images and a log file

    Science.gov (United States)

    Shiinoki, Takehiro; Hanazawa, Hideki; Yuasa, Yuki; Fujimoto, Koya; Uehara, Takuya; Shibuya, Keiko

    2017-02-01

    A combined system comprising the TrueBeam linear accelerator and a new real-time tumour-tracking radiotherapy system, SyncTraX, was installed at our institution. The objectives of this study are to develop a method for the verification of respiratory-gated radiotherapy with SyncTraX using cine electronic portal image device (EPID) images and a log file and to verify this treatment in clinical cases. Respiratory-gated radiotherapy was performed using TrueBeam and the SyncTraX system. Cine EPID images and a log file were acquired for a phantom and three patients during the course of the treatment. Digitally reconstructed radiographs (DRRs) were created for each treatment beam using a planning CT set. The cine EPID images, log file, and DRRs were analysed using a developed software. For the phantom case, the accuracy of the proposed method was evaluated to verify the respiratory-gated radiotherapy. For the clinical cases, the intra- and inter-fractional variations of the fiducial marker used as an internal surrogate were calculated to evaluate the gating accuracy and set-up uncertainty in the superior-inferior (SI), anterior-posterior (AP), and left-right (LR) directions. The proposed method achieved high accuracy for the phantom verification. For the clinical cases, the intra- and inter-fractional variations of the fiducial marker were  ⩽3 mm and  ±3 mm in the SI, AP, and LR directions. We proposed a method for the verification of respiratory-gated radiotherapy with SyncTraX using cine EPID images and a log file and showed that this treatment is performed with high accuracy in clinical cases. This work was partly presented at the 58th Annual meeting of American Association of Physicists in Medicine.

  8. Remediation of uranium-contaminated soil using the Segmented Gate System and containerized vat leaching techniques: a cost effectiveness study

    International Nuclear Information System (INIS)

    Cummings, M.; Booth, S.R.

    1996-01-01

    Because it is difficult to characterize heterogeneously contaminated soils in detail and to excavate such soils precisely using heavy equipment, it is common for large quantities of uncontaminated soil to be removed during excavation of contaminated sites. Until now, volume reduction of radioactively contaminated soil depended upon manual screening and analysis of samples, a costly and impractical approach, particularly with large volumes of heterogeneously contaminated soil. The baseline approach for the remediation of soils containing radioactive waste is excavation, pretreatment, containerization, and disposal at a federally permitted landfill. However, disposal of low-level radioactive waste is expensive and storage capacity is limited. ThermoNuclean's Segmented Gate System (SGS) removes only the radioactively contaminated soil, in turn greatly reducing the volume of soils that requires disposal. After processing using the SGS, the fraction of contaminated soil is processed using the containerized vat leaching (CVL) system developed at LANL. Uranium is leached out of the soil in solution. The uranium is recovered with an ion exchange resin, leaving only a small volume of liquid low-level waste requiring disposal. The reclaimed soil can be returned to its original location after treatment with CVL

  9. Mobile phone messaging reminders for attendance at healthcare appointments.

    Science.gov (United States)

    Gurol-Urganci, Ipek; de Jongh, Thyra; Vodopivec-Jamsek, Vlasta; Atun, Rifat; Car, Josip

    2013-12-05

    This review is an update of the original Cochrane review published in July 2012. Missed appointments are a major cause of inefficiency in healthcare delivery with substantial monetary costs for the health system, leading to delays in diagnosis and appropriate treatment. Patients' forgetfulness is one of the main reasons for missed appointments. Patient reminders may help reduce missed appointments. Modes of communicating reminders for appointments to patients include face-to-face communication, postal messages, calls to landlines or mobile phones, and mobile phone messaging. Mobile phone messaging applications, such as Short Message Service (SMS) and Multimedia Message Service (MMS), could provide an important, inexpensive delivery medium for reminders for healthcare appointments. To update our review assessing the effects of mobile phone messaging reminders for attendance at healthcare appointments. Secondary objectives include assessment of costs; health outcomes; patients' and healthcare providers' evaluation of the intervention and perceptions of safety; and possible harms and adverse effects associated with the intervention. Original searches were run in June 2009. For this update, we searched the Cochrane Central Register of Controlled Trials (CENTRAL,The Cochrane Library 2012, Issue 8), MEDLINE (OvidSP) (January 1993 to August 2012), EMBASE (OvidSP) (January 1993 to August 2012), PsycINFO (OvidSP) (January 1993 to August 2012) and CINAHL (EbscoHOST) (January 1993 to August 2012). We also reviewed grey literature (including trial registers) and reference lists of articles. Randomised controlled trials (RCTs) assessing mobile phone messaging as reminders for healthcare appointments. We only included studies in which it was possible to assess effects of mobile phone messaging independent of other technologies or interventions.   Two review authors independently assessed all studies against the inclusion criteria, with any disagreements resolved by a third

  10. Gated or ungated : water control in government-built irrigation systems : comparative research in Nepal

    NARCIS (Netherlands)

    Pradhan, T.M.S.

    1996-01-01


    The control, allocation and distribution, of water is the core process of an irrigation system. It is the process by which the available water is divided and distributed to the smaller irrigation units within the system, which in turn is distributed further down to the individual water

  11. Simulation of a quantum NOT gate for a single qutrit system

    Indian Academy of Sciences (India)

    arises. In particular, a three-level system or qutrit has attracted the attention [9]. The qutrit has proved to be more efficient than qubit systems for executing some tasks. For instance, for quantum key distribution it provides better security than that obtained by employing two-level encoding protocols [10,11]. In fact, it has been ...

  12. A quantum Fredkin gate.

    Science.gov (United States)

    Patel, Raj B; Ho, Joseph; Ferreyrol, Franck; Ralph, Timothy C; Pryde, Geoff J

    2016-03-01

    Minimizing the resources required to build logic gates into useful processing circuits is key to realizing quantum computers. Although the salient features of a quantum computer have been shown in proof-of-principle experiments, difficulties in scaling quantum systems have made more complex operations intractable. This is exemplified in the classical Fredkin (controlled-SWAP) gate for which, despite theoretical proposals, no quantum analog has been realized. By adding control to the SWAP unitary, we use photonic qubit logic to demonstrate the first quantum Fredkin gate, which promises many applications in quantum information and measurement. We implement example algorithms and generate the highest-fidelity three-photon Greenberger-Horne-Zeilinger states to date. The technique we use allows one to add a control operation to a black-box unitary, something that is impossible in the standard circuit model. Our experiment represents the first use of this technique to control a two-qubit operation and paves the way for larger controlled circuits to be realized efficiently.

  13. Multiple Gate Delay Tracking Structures for GNSS Signals and Their Evaluation with Simulink, SystemC, and VHDL

    Directory of Open Access Journals (Sweden)

    Heikki Hurskainen

    2008-01-01

    Full Text Available Accurate delay tracking in multipath environments is one of the prerequisites of modern GNSS receivers. Several solutions have been proposed in the literature, both feedback and feedforward. However, this topic is still under active research focus, especially for mass-market receivers, where selection of lowcomplexity, nonpatented methods is preferred. Among the most encountered delay tracking structures implemented in today's receivers, we have the narrow correlator and the double-delta correlators. Both are heavily covered by various patents. The purpose of this paper is to introduce a new, generic structure, called multiple gate delay (MGD structure, which covers also the patented correlators but offers much more flexibility in the design process. We show how the design parameters of such a structure can be optimized, we argue the performance of this structure via detailed simulation results based on various simulators, such as Matlab/Simulink-based tool, GRANADA, and we test the implementation feasibility of MGD structures on actual devices, via SystemC and FPGA prototyping. One of the main advantages of the proposed structure is its high degree of flexibility, which allows the designer to choose among, to the authors' knowledge, nonpatented solutions with delay tracking accuracy comparable with that of the current state-of-art trackers.

  14. Field Programmable Gate Array (FPGA Respiratory Monitoring System Using a Flow Microsensor and an Accelerometer

    Directory of Open Access Journals (Sweden)

    Mellal Idir

    2017-04-01

    Full Text Available This paper describes a non-invasive system for respiratory monitoring using a Micro Electro Mechanical Systems (MEMS flow sensor and an IMU (Inertial Measurement Unit accelerometer. The designed system is intended to be wearable and used in a hospital or at home to assist people with respiratory disorders. To ensure the accuracy of our system, we proposed a calibration method based on ANN (Artificial Neural Network to compensate the temperature drift of the silicon flow sensor. The sigmoid activation functions used in the ANN model were computed with the CORDIC (COordinate Rotation DIgital Computer algorithm. This algorithm was also used to estimate the tilt angle in body position. The design was implemented on reconfigurable platform FPGA.

  15. GATE simulation of a new design of pinhole SPECT system for small animal brain imaging

    International Nuclear Information System (INIS)

    Ozsahin, D. Uzun; Bläckberg, L.; Fakhri, G. El; Sabet, H.

    2017-01-01

    Small animal SPECT imaging has gained an increased interest over the past decade since it is an excellent tool for developing new drugs and tracers. Therefore, there is a huge effort on the development of cost-effective SPECT detectors with high capabilities. The aim of this study is to simulate the performance characteristics of new designs for a cost effective, stationary SPECT system dedicated to small animal imaging with a focus on mice brain. The conceptual design of this SPECT system platform, Stationary Small Animal SSA-SPECT, is to use many pixelated CsI:TI detector modules with 0.4 mm × 0.4 mm pixels in order to achieve excellent intrinsic detector resolution where each module is backed by a single pinhole collimator with 0.3 mm hole diameter. In this work, we present the simulation results of four variations of the SSA-SPECT platform where the number of detector modules and FOV size is varied while keeping the detector size and collimator hole size constant. Using the NEMA NU-4 protocol, we performed spatial resolution, sensitivity, image quality simulations followed by a Derenzo-like phantom evaluation. The results suggest that all four SSA-SPECT systems can provide better than 0.063% system sensitivity and < 1.5 mm FWHM spatial resolution without resolution recovery or other correction techniques. Specifically, SSA-SPECT-1 showed a system sensitivity of 0.09% in combination with 1.1 mm FWHM spatial resolution.

  16. Council Appointed Mayors in Spain: Effects on Local Democracy

    Directory of Open Access Journals (Sweden)

    María Jesús García García

    2017-03-01

    Full Text Available This paper deals with the influence of having council appointed mayors on local governments. Five elements of local government systems are considered: the electoral system and its influence on the political composition of the local government; the local government structure and the distribution of functions and powers between mayor and council; the role of political parties; scrutiny of the executive and accountability; and citizen participation. This analysis highlights the effect that a council appointed mayor system has in terms of accountability and legitimacy, transparency and efficiency. KEYWORDS Local government systems, directly elected mayors, local governance, council appointed mayors, Local Government Structure; Political Parties; Citizen Participation; Accountability. El presente artículo toma en consideración los efectos que el sistema de elección del Alcalde tiene sobre la democracia local, basándose en la consideración cinco aspectos: el sistema electoral y su influencia en la composición política de las administraciones locales; la estructura de la administración local y la distribución de funciones entre los alcaldes y el pleno municipal; el papel de los partidos políticos; los mecanismos de control del ejecutivo local y la participación ciudadana. El estudio subraya especialmente la incidencia que el sistema de elección del alcalde por los concejales tiene en relación con los principios de responsabilidad, legitimidad, transparencia y eficiencia de la gestión local. PALABRAS CLAVE Gobierno local, elección directa de los alcaldes, elección indirecta de los alcaldes, estructura del gobierno local, partidos políticos, participación ciudadana, responsabilidad política.

  17. Men's Educational Group Appointments in Rural Nicaragua.

    Science.gov (United States)

    Campbell, Bruce B; Gonzalez, Hugo; Campbell, McKenzie; Campbell, Kent

    2017-03-01

    Men's preventive health and wellness is largely neglected in rural Nicaragua, where a machismo culture prevents men from seeking health care. To address this issue, a men's educational group appointment model was initiated at a rural health post to increase awareness about hypertension, and to train community health leaders to measure blood pressure. Men's hypertension workshops were conducted with patient knowledge pretesting, didactic teaching, and posttesting. Pretesting and posttesting performances were recorded, blood pressures were screened, and community leaders were trained to perform sphygmomanometry. An increase in hypertension-related knowledge was observed after every workshop and community health leaders demonstrated proficiency in sphygmomanometry. In addition, several at-risk patients were identified and follow-up care arranged. Men's educational group appointments, shown to be effective in the United States in increasing patient knowledge and satisfaction, appear to function similarly in a resource-constrained environment and may be an effective mechanism for reaching underserved men in Nicaragua.

  18. 25 CFR 11.706 - Appointment and duties of appraiser.

    Science.gov (United States)

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false Appointment and duties of appraiser. 11.706 Section 11... OFFENSES AND LAW AND ORDER CODE Probate Proceedings § 11.706 Appointment and duties of appraiser. (a) Upon ordering an estate to be probated, the court shall appoint a disinterested and competent person as an...

  19. Factors influencing non-attendance of clinic appointments in ...

    African Journals Online (AJOL)

    without an appointment, with an average of eight patients per day missing their appointment. The low rate of compliance with clinic appointments was of concern for the physicians at both the diabetes clinics. Prior to the current study, the reasons for non-attendance had not been examined. Materials and methods. A sample ...

  20. 25 CFR 11.610 - Appointment of guardians.

    Science.gov (United States)

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false Appointment of guardians. 11.610 Section 11.610 Indians... ORDER CODE Domestic Relations § 11.610 Appointment of guardians. The court shall have the jurisdiction to appoint or remove legal guardians for minors and for persons who are incapable of managing their...

  1. Assessment of the Correlation between Appointment Scheduling and Patient Satisfaction in a Pediatric Dental Setup

    Directory of Open Access Journals (Sweden)

    Amar N. Katre

    2014-01-01

    Full Text Available Introduction. The practice of modern pediatric dentistry requires delivery of quality care in combination with adherence to excellent business as well as time management principles. A definite appointment schedule should be presented to the parents on the first or second appointment. More importantly, the prescribed schedule should be followed to the best of the professional abilities of the pediatric dentist. Aims. The aim of the study was to assess the co-relation between appointment scheduling and patient satisfaction in a pediatric dental setup with the objective of understanding the parameters related to appointment scheduling to increase patient satisfaction. Method. A total of 40 patients, who visited the Department of Pediatric and Preventive Dentistry, YMT Dental College & Hospital, for dental treatment were selected on a random basis. A questionnaire with a set of 6 questions with a rating scale of 1–5 to assess the patient satisfaction related to appointment scheduling was prepared. Results. A significant number of the patients were happy with the existing appointment scheduling system barring a few exceptions.

  2. New gate opening hours

    CERN Multimedia

    GS Department

    2009-01-01

    Please note the new opening hours of the gates as well as the intersites tunnel from the 19 May 2009: GATE A 7h - 19h GATE B 24h/24 GATE C 7h - 9h\t17h - 19h GATE D 8h - 12h\t13h - 16h GATE E 7h - 9h\t17h - 19h Prévessin 24h/24 The intersites tunnel will be opened from 7h30 to 18h non stop. GS-SEM Group Infrastructure and General Services Department

  3. Simulation of a quantum NOT gate for a single qutrit system

    Indian Academy of Sciences (India)

    Estado de México, CP 56615, México. ∗. Corresponding author. E-mail: vlkmanuel@uaemex.mx. MS received 30 August 2014; revised 23 March 2015; accepted 30 March 2015. DOI: 10.1007/s12043-015-1116-3; ePublication: 4 November 2015. Abstract. A three-level system based an a three-level atom interacting with a ...

  4. Evaluation of a decision support system for interpretation of myocardial perfusion gated SPECT.

    Science.gov (United States)

    Lomsky, Milan; Gjertsson, Peter; Johansson, Lena; Richter, Jens; Ohlsson, Mattias; Tout, Deborah; van Aswegen, Andries; Underwood, S Richard; Edenbrandt, Lars

    2008-08-01

    We have recently presented a decision support system for interpreting myocardial perfusion scintigraphy (MPS). In this study, we wanted to evaluate the system in a separate hospital from where it was trained and to compare it with a quantification software package. A completely automated method based on neural networks was trained for the interpretation of MPS regarding myocardial ischaemia and infarction using 418 MPS from one hospital. Features from each examination describing rest and stress perfusion, regional and global function were used as inputs to different neural networks. After the training session, the system was evaluated using 532 MPS from another hospital. The test images were also processed with the quantification software package Emory Cardiac Toolbox (ECTb). The images were interpreted by experienced clinicians at both the training and the test hospital, regarding the presence or absence of myocardial ischaemia and/or infarction and these interpretations were used as gold standard. The neural network showed a sensitivity of 90% and a specificity of 85% for myocardial ischaemia. The specificity for the ECTb was 46% (p neural network sensitivity for myocardial infarction was 89% and the specificity 96%. The corresponding specificity for the ECTb was 54% (p neural networks presents interpretations more similar to experienced clinicians compared to a conventional automated quantification software package. This study shows the feasibility of disseminating the expertise of experienced clinicians to less experienced physicians by the use of neural networks.

  5. Field Programmable Gate Array Based Parallel Strapdown Algorithm Design for Strapdown Inertial Navigation Systems

    Directory of Open Access Journals (Sweden)

    Long-Hua Ma

    2011-08-01

    Full Text Available A new generalized optimum strapdown algorithm with coning and sculling compensation is presented, in which the position, velocity and attitude updating operations are carried out based on the single-speed structure in which all computations are executed at a single updating rate that is sufficiently high to accurately account for high frequency angular rate and acceleration rectification effects. Different from existing algorithms, the updating rates of the coning and sculling compensations are unrelated with the number of the gyro incremental angle samples and the number of the accelerometer incremental velocity samples. When the output sampling rate of inertial sensors remains constant, this algorithm allows increasing the updating rate of the coning and sculling compensation, yet with more numbers of gyro incremental angle and accelerometer incremental velocity in order to improve the accuracy of system. Then, in order to implement the new strapdown algorithm in a single FPGA chip, the parallelization of the algorithm is designed and its computational complexity is analyzed. The performance of the proposed parallel strapdown algorithm is tested on the Xilinx ISE 12.3 software platform and the FPGA device XC6VLX550T hardware platform on the basis of some fighter data. It is shown that this parallel strapdown algorithm on the FPGA platform can greatly decrease the execution time of algorithm to meet the real-time and high precision requirements of system on the high dynamic environment, relative to the existing implemented on the DSP platform.

  6. Molecular logic gate arrays.

    Science.gov (United States)

    de Silva, A Prasanna

    2011-03-01

    Chemists are now able to emulate the ideas and instruments of mathematics and computer science with molecules. The integration of molecular logic gates into small arrays has been a growth area during the last few years. The design principles underlying a collection of these cases are examined. Some of these computing molecules are applicable in medical- and biotechnologies. Cases of blood diagnostics, 'lab-on-a-molecule' systems, and molecular computational identification of small objects are included. Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  7. Electrophysiological and Pharmacological Analyses of Nav1.9 Voltage-Gated Sodium Channel by Establishing a Heterologous Expression System

    Science.gov (United States)

    Zhou, Xi; Xiao, Zhen; Xu, Yan; Zhang, Yunxiao; Tang, Dongfang; Wu, Xinzhou; Tang, Cheng; Chen, Minzhi; Shi, Xiaoliu; Chen, Ping; Liang, Songping; Liu, Zhonghua

    2017-01-01

    Nav1. 9 voltage-gated sodium channel is preferentially expressed in peripheral nociceptive neurons. Recent progresses have proved its role in pain sensation, but our understanding of Nav1.9, in general, has lagged behind because of limitations in heterologous expression in mammal cells. In this work, functional expression of human Nav1.9 (hNav1.9) was achieved by fusing GFP to the C-terminal of hNav1.9 in ND7/23 cells, which has been proved to be a reliable method to the electrophysiological and pharmacological studies of hNav1.9. By using the hNav1.9 expression system, we investigated the electrophysiological properties of four mutations of hNav1.9 (K419N, A582T, A842P, and F1689L), whose electrophysiological functions have not been determined yet. The four mutations significantly caused positive shift of the steady-state fast inactivation and therefore increased hNav1.9 activity, consistent with the phenotype of painful peripheral neuropathy. Meanwhile, the effects of inflammatory mediators on hNav1.9 were also investigated. Impressively, histamine was found for the first time to enhance hNav1.9 activity, indicating its vital role in hNav1.9 modulating inflammatory pain. Taken together, our research provided a useful platform for hNav1.9 studies and new insight into mechanism of hNav1.9 linking to pain. PMID:29213238

  8. Development of a protection system for research reactor based in Field Programmable Gate Array - FPGA; Desenvolvimento de sistema de protecao para reator nuclear de pesquisa baseado em Field Programmable Gate Array - FPGA

    Energy Technology Data Exchange (ETDEWEB)

    Martins, Roque Hudson da Silva

    2016-07-01

    This study presents a implementation purpose of a protection system for research nuclear reactors by using a programed device FPGA (Field Programmable Gate Array). As well as logic protection method involved on an automatic shutdown (TRIP) of a reactor, that ensure the security on such systems. These new control and operation mechanics are developed to guarantee that the security limits of a power plant are not exceeded, these mechanics can work isolated or in groups to safe guard the security levels. For this implementation to be completed, there will be presented the main aspects and concepts referred to protection systems, mostly about research nuclear reactors, with some applications terms exposed. The system proposed at this paper was developed following the VHDL (Very High Speed Integrated Circuits) hardware describing language, and the Modelsim software from Altera Software to program the automatic turning off routines, and hypothetical simulations for such. The results show that for every software application for supporting nuclear reactors, like security devices, they have to meet the IEC 60880 criteria. This paper have great importance, seeing that nuclear reactor security systems, are a basic element for ensure the reactor security. (author)

  9. Patients’ Perspective on the Value of Medication Management Appointments

    Directory of Open Access Journals (Sweden)

    Mario Cruz

    2015-05-01

    Full Text Available Objectives: There is ongoing concern that psychiatric medication management appointments add little value to care. The present study attempted to address this concern by capturing depressed patients’ views and opinions about the value of psychiatric medication management appointments. Methods: Seventy-eight semi-structured interviews were performed with white and African American depressed patients post medication management appointments. These interviews tapped patients’ views and opinions about the value of attending medication management appointments. Analysis: An iterative thematic analysis was performed. Findings: Patients reported greater appointment value when appointments included obtaining medications, discussing the need for medication changes or dose adjustments, and discussing the impact of medications on their illness. Additionally, greater appointment value was perceived by patients when there were non-medical conversations about life issues, immediate outcomes from the appointment such as motivation to continue in care, and specific qualities of providers that were appealing to patients. Conclusions: Patients’ perceived value of psychiatric medication management appointments is complex. Though important patient outcomes are obtaining medicine and perceiving improvement in their mental health, there are other valued appointment and provider factors. Some of these other valued factors embedded within medication management appointments could have therapeutic properties. These findings have implications for future clinical research and service delivery.

  10. Gate Crashers.

    Science.gov (United States)

    Wilson, David L.

    1993-01-01

    Campus computing officials are working to improve security against computer hackers because of concerns about privacy, accidental or intentional damage to systems, and impediments to legitimate system users. Increasingly, public law enforcement authorities are called in but do not always take the problem seriously. (MSE)

  11. Electrocardiographic gating of list mode data with a positron emission tomography system that utilizes wobbling motion to achieve uniform sampling

    International Nuclear Information System (INIS)

    Gaeta, J.M.; Yerian, K.A.; Mullani, N.A.

    1986-01-01

    An interactive software package has been developed for gating of list mode data acquired with PET. The package supports: histogram displays (ie. for determining an acceptable beat interval length window), automatic rejection of beats outside the window, forward or backward gating capabilities, capability of specifying the position of the gating interval, and of the time interval within the list mode study to be reformatted. The interaction of PET wobble motion frequency and heart beat frequency may result in image non-uniformities (ringing artifacts), due to incomplete wobble sampling. Therefore, the reconstruction software incorporates a very simple scheme for correcting for the amount of time spent at each wobble position and allowing for the decay of short lived isotopes such as Rubidium-82 (Rb-82). Rb-82 myocardial uptake images free of non-uniformity artifacts and quantitatively accurate have been reconstructed for 10 different dog studies, and 8 patient studies. Multi-slice frames at discrete portions of the heart cycle (i.e. End Diastole) and multi-gated sequences for cine display have been produced

  12. Coronary imaging quality in routine ECG-gated multidetector CT examinations of the entire thorax: preliminary experience with a 64-slice CT system in 133 patients

    International Nuclear Information System (INIS)

    Delhaye, Damien; Remy-Jardin, Martine; Salem, Randa; Teisseire, Antoine; Khalil, Chadi; Remy, Jacques; Delannoy-Deken, Valerie; Duhamel, Alain

    2007-01-01

    To evaluate image quality in the assessment of the coronary arteries during routine ECG-gated multidetector CT (MDCT) of the chest. One hundred and thirty three patients in sinus rhythm underwent an ECG-gated CT angiographic examination of the entire chest without β-blockers with a 64-slice CT system. In 127 patients (95%), it was possible to assess the coronary arteries partially or totally; coronary artery imaging failed in six patients (5%), leading to a detailed description of the coronary arteries in 127 patients. Considering ten coronary artery segments per patient, 75% of coronary segments were assessable (948/1270 segments). When the distal segments were excluded from the analysis (i.e., seven coronary segments evaluated per patient), the percentage of assessable segments was 86% (768/889 proximal and mid coronary segments) and reached 93% (474/508) when assessing proximal segments exclusively. The mean number of assessable segments was significantly higher in patients with a heart rate ≤80 bpm (n=95) than in patients with a heart rate >80 bpm (n=38) (p<0.002). Proximal and mid-coronary segments can be adequately assessed during a whole-chest ECG-gated CT angiographic examination without administration of β-blockers in patients with a heart rate below 80 bpm. (orig.)

  13. TU-AB-BRA-10: Treatment of Gastric MALT Lymphoma Utilizing a Magnetic Resonance Image-Guided Radiation Therapy (MR-IGRT) System: Evaluation of Gating Feasibility

    Energy Technology Data Exchange (ETDEWEB)

    Mazur, T; Gach, H; Chundury, A; Fischer-Valuck, B; Huang, J; Thomas, M; Green, O [Washington University School of Medicine, St. Louis, MO (United States)

    2016-06-15

    Purpose: To evaluate the feasibility of real-time, real-anatomy tracking and gating for gastric lymphoma patients treated with magnetic resonance image-guided radiation therapy (MR-IGRT) Methods: Over the last 2 years, 8 patients with gastric lymphoma were treated with 0.3-T, Co-60 MR-IGRT. Post-treatment analysis of real-time cine imaging in the sagittal plane during each patient’s treatment revealed significant motion of the stomach. While this motion was accounted for with generous PTV margins, the system’s capability for real-time, real-anatomy tracking could be used to reduce treatment margins by gating. However, analysis was needed for the feasibility of gating using only the single available sagittal imaging plane. While any plane may be chosen, if the stomach moves differently where it is not being observed, there may potentially be a mistreatment. To that end, imaging with healthy volunteers was done to ascertain stomach motion over 2–4 min by analyzing multiple parallel sagittal and coronal planes 0.75 cm apart. The stomach was contoured on every slice, and the mean displacement between pairs of contour centroids was used to determine the amount of overall motion. Results: The mean displacement of the centroid in the image plane was 4.3 ± 0.7 mm. The greatest observed motion was more medial with respect to the patient, and less motion laterally, which implies that gating on a plane located closer to MRI isocenter will provide the more conservative scenario as it will turn the radiation delivery off when the stomach is observed to move outside a predetermined boundary. Conclusion: The stomach was observed to move relatively uniformly throughout, with maximum extent of motion closer to where most MRI systems have the best spatial integrity (near isocenter). Analysis of possible PTV margins from the healthy volunteer study (coupled with previous patient data on interfraction volumetric stomach deformation) is pending.

  14. Behavioral changes during dental appointments in children having tooth extractions

    Directory of Open Access Journals (Sweden)

    Mariana Gonzalez Cademartori

    2017-01-01

    Full Text Available Background: Tooth extractions are associated with anxiety-related situations that can cause behavioral problems in pediatric dental clinics. Aim: We aimed to describe the behavior of children during tooth extraction appointments, compare it to their behavior in preceding and subsequent dental appointments, and assess the behavioral differences according to gender, age, type of dentition, and reason for extraction. Settings and Design: This was a retrospective study based on information obtained from records of children between 6 and 13 years of age who were cared for at the Dentistry School in Pelotas, Brazil. Materials and Methods: Child behavior was assessed during the dental appointment that preceded the tooth extraction, during the tooth extraction appointment, and in the subsequent dental appointment using the Venham Behavior Rating Scale. Statistical Analysis: Results were analyzed using the Pearson Chi-square and McNemar tests. Results: Eighty-nine children were included. Cooperative behavior prevailed in all the dental appointments. The prevalence of “mild/intense protest” was higher in the tooth extraction appointments than in the previous or subsequent dental appointments (P < 0.001. No significant differences in behavior were detected between the type of dentition (primary or permanent teeth, reason for extraction or gender. Conclusion: In this sample of children treated at a dental school, the occurrence of uncooperative behavior was higher during the tooth extraction appointments than in the preceding and subsequent dental appointments.

  15. Respiratory gating in cardiac PET

    DEFF Research Database (Denmark)

    Lassen, Martin Lyngby; Rasmussen, Thomas; Christensen, Thomas E

    2017-01-01

    BACKGROUND: Respiratory motion due to breathing during cardiac positron emission tomography (PET) results in spatial blurring and erroneous tracer quantification. Respiratory gating might represent a solution by dividing the PET coincidence dataset into smaller respiratory phase subsets. The aim...... stress (82)RB-PET. Respiratory rates and depths were measured by a respiratory gating system in addition to registering actual respiratory rates. Patients undergoing adenosine stress showed a decrease in measured respiratory rate from initial to later scan phase measurements [12.4 (±5.7) vs 5.6 (±4.......7) min(-1), P PET...

  16. Reductions in the variations of respiration signals for respiratory-gated radiotherapy when using the video-coaching respiration guiding system

    Science.gov (United States)

    Lee, Hyun Jeong; Yea, Ji Woon; Oh, Se An

    2015-07-01

    Respiratory-gated radiation therapy (RGRT) has been used to minimize the dose to normal tissue in lung-cancer radiotherapy. The present research aims to improve the regularity of respiration in RGRT by using a video-coached respiration guiding system. In the study, 16 patients with lung cancer were evaluated. The respiration signals of the patients were measured by using a realtime position management (RPM) respiratory gating system (Varian, USA), and the patients were trained using the video-coaching respiration guiding system. The patients performed free breathing and guided breathing, and the respiratory cycles were acquired for ~5 min. Then, Microsoft Excel 2010 software was used to calculate the mean and the standard deviation for each phase. The standard deviation was computed in order to analyze the improvement in the respiratory regularity with respect to the period and the displacement. The standard deviation of the guided breathing decreased to 48.8% in the inhale peak and 24.2% in the exhale peak compared with the values for the free breathing of patient 6. The standard deviation of the respiratory cycle was found to be decreased when using the respiratory guiding system. The respiratory regularity was significantly improved when using the video-coaching respiration guiding system. Therefore, the system is useful for improving the accuracy and the efficiency of RGRT.

  17. Cloning and expression of ligand-gated ion-channel receptor L2 in central nervous system

    International Nuclear Information System (INIS)

    Houtani, Takeshi; Munemoto, Yumi; Kase, Masahiko; Sakuma, Satoru; Tsutsumi, Toshiyuki; Sugimoto, Tetsuo

    2005-01-01

    An orphan receptor of ligand-gated ion-channel type (L2, also termed ZAC according to the presence of zinc ion for channel activation) was identified by computer-assisted search programs on human genome database. The L2 protein shares partial homology with serotonin receptors 5HT3A and 5HT3B. We have cloned L2 cDNA derived from human caudate nucleus and characterized the exon-intron structure as follows: (1) The L2 protein has four transmembrane regions (M1-M4) and a long cytoplasmic loop between M3 and M4. (2) The sequence is conserved in species including chimpanzee, dog, cow, and opossum. (3) Nine exons form its protein-coding region and especially exon 5 corresponds to a disulfide bond region on the amino-terminal side. Our analysis using multiple tissue cDNA panels revealed that at least two splicing variants of L2 mRNA are present. The cDNA PCR amplification study revealed that L2 mRNA is expressed in tissues including brain, pancreas, liver, lung, heart, kidney, and skeletal muscle while 5HT3A mRNA could be detected in brain, heart, placenta, lung, kidney, pancreas, and skeletal muscle, and 5HT3B mRNA in brain, kidney, and skeletal muscle, suggesting different significance in tissue expression of these receptors. Regional expression of L2 mRNA and protein was examined in brain. The RT-PCR studies confirmed L2 mRNA expression in hippocampus, striatum, amygdala, and thalamus in adult brain. The L2 protein was immunolocalized by using antipeptide antibodies. Immunostained tissue sections revealed that L2-like immunoreactivity was dominantly expressed in the hippocampal CA3 pyramidal cells and in the polymorphic layer of the dentate gyrus. We analyzed the expression of L2 protein in HEK293 cells using GFP fusion protein reporter system. Western blots revealed that L2 protein confers sugar chains on the extracellular side. In transfected HEK293 cells, cellular membranes and intracellular puncta were densely labeled with GFP, suggesting selective dispatch to the

  18. Construction of a high-efficiency cloning system using the Golden Gate method and I-SceI endonuclease for targeted gene replacement in Bacillus anthracis.

    Science.gov (United States)

    Wang, Tiantian; Wang, Dongshu; Lyu, Yufei; Feng, Erling; Zhu, Li; Liu, Chunjie; Wang, Yanchun; Liu, Xiankai; Wang, Hengliang

    2018-02-10

    To investigate gene function in Bacillus anthracis, a high-efficiency cloning system is required with an increased rate of allelic exchange. Golden Gate cloning is a molecular cloning strategy allowing researchers to simultaneously and directionally assemble multiple DNA fragments to construct target plasmids using type IIs restriction enzymes and T4 DNA ligase in the same reaction system. Here, a B. anthracis S-layer protein EA1 allelic exchange vector was successfully constructed using the Golden Gate method. No new restriction sites were introduced into this knockout vector, and seamless assembly of the DNA fragments was achieved. To elevate the efficiency of homologous recombination between the allelic exchange vector and chromosomal DNA, we introduced an I-SceI site into the allelic exchange vector. The eag gene was successfully knocked out in B. anthracis using this vector. Simultaneously, the allelic exchange vector construction method was developed into a system for generating B. anthracis allelic exchange vectors. To verify the effectiveness of this system, some other allelic exchange vectors were constructed and gene replacements were performed in B. anthracis. It is speculated that this gene knockout vector construction system and high-efficiency targeted gene replacement using I-SceI endonuclease can be applied to other Bacillus spp. Copyright © 2018 The Authors. Published by Elsevier B.V. All rights reserved.

  19. Dynamic Power Reduction of Digital Circuits by ClockGating

    OpenAIRE

    Varsha Dewre; Rakesh Mandliya

    2017-01-01

    In this paper we have presented clock gating process for low power VLSI (very large scale integration) circuit design. Clock gating is one of the most quite often used systems in RTL to shrink dynamic power consumption without affecting the performance of the design. One process involves inserting gating requisites in the RTL, which the synthesis tool translates to clock gating cells in the clock-path of a register bank. This helps to diminish the switching activity on the clock network, ther...

  20. Demand management: an audit of chemical pathology test rejections by an electronic gate-keeping system at an academic hospital in Cape Town.

    Science.gov (United States)

    Smit, Ida; Zemlin, Annalise E; Erasmus, Rajiv T

    2015-07-01

    Demand management is an area of laboratory activity, which is becoming increasingly important. Within the health-care system, demand management can be defined as the use of health resources to maximise its utility. Tygerberg Hospital has introduced an electronic gate-keeping system. Chemistry tests which generate the highest cost are subjected to this system and may be automatically rejected according to a set of rules. This study aimed: (1) to identify the number of chemistry tests rejected by the eGK; (2) to identify which of these rejected tests were subsequently restored and (3) to assess the impact of rejections on clinical outcome and cost-saving. A retrospective audit was conducted to determine the number of chemistry tests rejected and subsequently restored over a 6-month period. The case-notes of patients for whom requested tests previously rejected had been restored were randomly selected and investigated to assess clinical impact. Any cost-saving was calculated. A total of 68,480 tests were subjected to gate-keeping, and 4605 tests (6.7%) were rejected while 679 (14.7%) of these were restored by the requestor phoning the laboratory after obtaining authorisation. After examining a subset of clinical notes it was found that in most cases (80%), patient care was unaffected. The total cost saved was £ 25,387. The majority of the rejected tests were unnecessary and following rejection, real savings were made. Electronic gate-keeping is a simple, effective and sustainable method of demand management. © The Author(s) 2015 Reprints and permissions: sagepub.co.uk/journalsPermissions.nav.

  1. 48 CFR 245.7001 - Selection, appointment, and termination.

    Science.gov (United States)

    2010-10-01

    ... contracting activity for the Defense Logistics Agency, or the head of the contract administration office for... officers, the appointment authority shall consider experience, training, education, business acumen...

  2. Energy spectrum, exchange interaction, and gate crosstalk in a system with a pair of double quantum dots: A molecular-orbital calculation

    Science.gov (United States)

    Yang, Xu-Chen; Wang, Xin

    2017-05-01

    We present a theoretical study of a four-electron four-quantum-dot system based on molecular-orbital methods, which hosts a pair of singlet-triplet spin qubits. We took into account the admixture of electron wave functions in all dots, and we found that this mixing of wave functions has consequences to the energy spectrum, exchange interaction, and gate crosstalk of the system. Specifically, we found that when the two singlet-triplet qubits are close enough, some of the states are no longer dominated by the computational basis states, and the exchange interaction cannot simply be understood as the energy difference between the singlet and triplet states. Using the Hund-Mulliken calculation of the Hubbard parameters, we characterized the effective exchange interaction of the system, and we found good agreement with results calculated by taking energy differences where applicable. We studied the two commonly conceived schemes coupling two qubits, namely the exchange and capacitive coupling, and we found that when the interqubit distance is at certain intermediate values, the two kinds of coupling are comparable in strength, complicating the analyses of the evolution of the two qubits. We also investigated the gate crosstalk in the system due to the quantum-mechanical mixing of electron states, and we found that while this effect is typically very weak, it should not be ignored if the spacing between the qubits is similar to or less than the distance between the double dots that constitute the qubit.

  3. Gate errors in solid-state quantum-computer architectures

    International Nuclear Information System (INIS)

    Hu Xuedong; Das Sarma, S.

    2002-01-01

    We theoretically consider possible errors in solid-state quantum computation due to the interplay of the complex solid-state environment and gate imperfections. In particular, we study two examples of gate operations in the opposite ends of the gate speed spectrum, an adiabatic gate operation in electron-spin-based quantum dot quantum computation and a sudden gate operation in Cooper-pair-box superconducting quantum computation. We evaluate quantitatively the nonadiabatic operation of a two-qubit gate in a two-electron double quantum dot. We also analyze the nonsudden pulse gate in a Cooper-pair-box-based quantum-computer model. In both cases our numerical results show strong influences of the higher excited states of the system on the gate operation, clearly demonstrating the importance of a detailed understanding of the relevant Hilbert-space structure on the quantum-computer operations

  4. The unilateral appointment of co-arbitrators

    DEFF Research Database (Denmark)

    Tufte-Kristensen, Johan

    2016-01-01

    Contractual practices and the applicable law on the composition of three-member tribunals normally provide for each party to select a co-arbitrator unilaterally. This procedure may make the co-arbitrators appear partial and may lead to improper dissenting opinions and premature resignations, which...... may ultimately threaten the confidence in arbitration and arbitral awards, but the procedure does not remain common for nothing. The arbitration community therefore needs to reconsider the appointment procedure on a solid and deliberate basis, and such a basis is what the article provides. A number...... of experienced arbitration practitioners have advocated against the procedure for some of the reasons above, whereas other experienced arbitration practitioners have defended the procedure because of its practical advantages and underlying rationales. Each of the previous contributions to the debate sheds light...

  5. Gated equilibrium bloodpool scintigraphy

    International Nuclear Information System (INIS)

    Reinders Folmer, S.C.C.

    1981-01-01

    This thesis deals with the clinical applications of gated equilibrium bloodpool scintigraphy, performed with either a gamma camera or a portable detector system, the nuclear stethoscope. The main goal has been to define the value and limitations of noninvasive measurements of left ventricular ejection fraction as a parameter of cardiac performance in various disease states, both for diagnostic purposes as well as during follow-up after medical or surgical intervention. Secondly, it was attempted to extend the use of the equilibrium bloodpool techniques beyond the calculation of ejection fraction alone by considering the feasibility to determine ventricular volumes and by including the possibility of quantifying valvular regurgitation. In both cases, it has been tried to broaden the perspective of the observations by comparing them with results of other, invasive and non-invasive, procedures, in particular cardiac catheterization, M-mode echocardiography and myocardial perfusion scintigraphy. (Auth.)

  6. Characterization of a time-resolved non-contact scanning diffuse optical imaging system exploiting fast-gated single-photon avalanche diode detection

    Energy Technology Data Exchange (ETDEWEB)

    Di Sieno, Laura, E-mail: laura.disieno@polimi.it; Dalla Mora, Alberto; Contini, Davide [Politecnico di Milano, Dipartimento di Fisica, Piazza Leonardo Da Vinci 32, 20133 Milano (Italy); Wabnitz, Heidrun; Macdonald, Rainer [Physikalisch-Technische Bundesanstalt (PTB), Abbestr. 2-12, 10587 Berlin (Germany); Pifferi, Antonio [Politecnico di Milano, Dipartimento di Fisica, Piazza Leonardo Da Vinci 32, 20133 Milano (Italy); Istituto di Fotonica e Nanotecnologie, Consiglio Nazionale delle Ricerche, Piazza Leonardo da Vinci 32, 20133 Milano (Italy); Mazurenka, Mikhail [Physikalisch-Technische Bundesanstalt (PTB), Abbestr. 2-12, 10587 Berlin (Germany); Hannoversches Zentrum für Optische Technologien, Nienburger Str. 17, 30167 Hannover (Germany); Hoshi, Yoko [Department of Biomedical Optics, Medical Photonics Research Center, Hamamatsu University School of Medicine, Hamamatsu 431-3192 (Japan); Boso, Gianluca; Tosi, Alberto [Politecnico di Milano, Dipartimento di Elettronica, Informazione e Bioingegneria, Piazza Leonardo Da Vinci 32, 20133 Milano (Italy); Becker, Wolfgang [Becker and Hickl GmbH, Nahmitzer Damm 30, 12277 Berlin (Germany); Martelli, Fabrizio [Dipartimento di Fisica e Astronomia dell’Università degli Studi di Firenze, Via G. Sansone 1, Sesto Fiorentino, Firenze 50019 (Italy)

    2016-03-15

    We present a system for non-contact time-resolved diffuse reflectance imaging, based on small source-detector distance and high dynamic range measurements utilizing a fast-gated single-photon avalanche diode. The system is suitable for imaging of diffusive media without any contact with the sample and with a spatial resolution of about 1 cm at 1 cm depth. In order to objectively assess its performances, we adopted two standardized protocols developed for time-domain brain imagers. The related tests included the recording of the instrument response function of the setup and the responsivity of its detection system. Moreover, by using liquid turbid phantoms with absorbing inclusions, depth-dependent contrast and contrast-to-noise ratio as well as lateral spatial resolution were measured. To illustrate the potentialities of the novel approach, the characteristics of the non-contact system are discussed and compared to those of a fiber-based brain imager.

  7. MO-DE-207A-06: ECG-Gated CT Reconstruction for a C-Arm Inverse Geometry X-Ray System

    Energy Technology Data Exchange (ETDEWEB)

    Slagowski, JM; Dunkerley, DAP [MA Speidel, University of Wisconsin - Madison, Madison, WI (United States)

    2016-06-15

    Purpose: To obtain ECG-gated CT images from truncated projection data acquired with a C-arm based inverse geometry fluoroscopy system, for the purpose of cardiac chamber mapping in interventional procedures. Methods: Scanning-beam digital x-ray (SBDX) is an inverse geometry fluoroscopy system with a scanned multisource x-ray tube and a photon-counting detector mounted to a C-arm. In the proposed method, SBDX short-scan rotational acquisition is performed followed by inverse geometry CT (IGCT) reconstruction and segmentation of contrast-enhanced objects. The prior image constrained compressed sensing (PICCS) framework was adapted for IGCT reconstruction to mitigate artifacts arising from data truncation and angular undersampling due to cardiac gating. The performance of the reconstruction algorithm was evaluated in numerical simulations of truncated and non-truncated thorax phantoms containing a dynamic ellipsoid to represent a moving cardiac chamber. The eccentricity of the ellipsoid was varied at frequencies from 1–1.5 Hz. Projection data were retrospectively sorted into 13 cardiac phases. Each phase was reconstructed using IGCT-PICCS, with a nongated gridded FBP (gFBP) prior image. Surface accuracy was determined using Dice similarity coefficient and a histogram of the point distances between the segmented surface and ground truth surface. Results: The gated IGCT-PICCS algorithm improved surface accuracy and reduced streaking and truncation artifacts when compared to nongated gFBP. For the non-truncated thorax with 1.25 Hz motion, 99% of segmented surface points were within 0.3 mm of the 15 mm diameter ground truth ellipse, versus 1.0 mm for gFBP. For the truncated thorax phantom with a 40 mm diameter ellipse, IGCT-PICCS surface accuracy measured 0.3 mm versus 7.8 mm for gFBP. Dice similarity coefficient was 0.99–1.00 (IGCT-PICCS) versus 0.63–0.75 (gFBP) for intensity-based segmentation thresholds ranging from 25–75% maximum contrast. Conclusions: The

  8. MO-DE-207A-06: ECG-Gated CT Reconstruction for a C-Arm Inverse Geometry X-Ray System

    International Nuclear Information System (INIS)

    Slagowski, JM; Dunkerley, DAP

    2016-01-01

    Purpose: To obtain ECG-gated CT images from truncated projection data acquired with a C-arm based inverse geometry fluoroscopy system, for the purpose of cardiac chamber mapping in interventional procedures. Methods: Scanning-beam digital x-ray (SBDX) is an inverse geometry fluoroscopy system with a scanned multisource x-ray tube and a photon-counting detector mounted to a C-arm. In the proposed method, SBDX short-scan rotational acquisition is performed followed by inverse geometry CT (IGCT) reconstruction and segmentation of contrast-enhanced objects. The prior image constrained compressed sensing (PICCS) framework was adapted for IGCT reconstruction to mitigate artifacts arising from data truncation and angular undersampling due to cardiac gating. The performance of the reconstruction algorithm was evaluated in numerical simulations of truncated and non-truncated thorax phantoms containing a dynamic ellipsoid to represent a moving cardiac chamber. The eccentricity of the ellipsoid was varied at frequencies from 1–1.5 Hz. Projection data were retrospectively sorted into 13 cardiac phases. Each phase was reconstructed using IGCT-PICCS, with a nongated gridded FBP (gFBP) prior image. Surface accuracy was determined using Dice similarity coefficient and a histogram of the point distances between the segmented surface and ground truth surface. Results: The gated IGCT-PICCS algorithm improved surface accuracy and reduced streaking and truncation artifacts when compared to nongated gFBP. For the non-truncated thorax with 1.25 Hz motion, 99% of segmented surface points were within 0.3 mm of the 15 mm diameter ground truth ellipse, versus 1.0 mm for gFBP. For the truncated thorax phantom with a 40 mm diameter ellipse, IGCT-PICCS surface accuracy measured 0.3 mm versus 7.8 mm for gFBP. Dice similarity coefficient was 0.99–1.00 (IGCT-PICCS) versus 0.63–0.75 (gFBP) for intensity-based segmentation thresholds ranging from 25–75% maximum contrast. Conclusions: The

  9. Ultrathin gate valve for high vacuum operation

    Science.gov (United States)

    Ugiansky, R. J.

    1971-01-01

    Thin, compact, high-vacuum gate valve used to join two vacuum systems together demonstrates multiple operation reliability. Valve measurements and non-protruding handle make valve usable in confined areas.

  10. Key criteria in appointment of arbitrators in international arbitration

    Directory of Open Access Journals (Sweden)

    Bazil Oglindă

    2015-12-01

    Full Text Available Maybe in all situations the most important factor is the decision making person. In arbitration this person is the arbitrator. Knowing how to choose your arbitrator is the first step in knowing how to win your case. There are some important criteria that needs to be taken into account when appointing an arbitrator, like the independence and impartiality of the arbitrator, the experience in similar cases, knowledge of the system of law applicable to the contract and other backgrounds.Another important aspect is the number of arbitrators and the advantages and disadvantages of having one, three or more arbitrators. All those issues are very important when drafting the arbitration agreement and in matters of complex contracts it is of high importance to have legal advisors that will help you draft an agreement that will minimize risks and favor efficient arbitral proceedings.

  11. 41 CFR 302-2.4 - What is my effective transfer or appointment date?

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 4 2010-07-01 2010-07-01 false What is my effective transfer or appointment date? 302-2.4 Section 302-2.4 Public Contracts and Property Management Federal Travel Regulation System RELOCATION ALLOWANCES INTRODUCTION 2-EMPLOYEES ELIGIBILITY REQUIREMENTS General...

  12. Compliance with clinic appointments by hypertensive patients after ...

    African Journals Online (AJOL)

    Objective: Compliance with clinic appointment is one of the several ways to assess patients' adherence to treatment with varying rates of compliance with scheduled visits being reported. This study was carried out with the aim of assessing the level of compliance with clinic appointments of our hypertensive patients after ...

  13. 25 CFR 140.1 - Sole power to appoint.

    Science.gov (United States)

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false Sole power to appoint. 140.1 Section 140.1 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR FINANCIAL ACTIVITIES LICENSED INDIAN TRADERS § 140.1 Sole power to appoint. The Commissioner of Indian Affairs shall have the sole power and authority to...

  14. 5 CFR 302.401 - Selection and appointment.

    Science.gov (United States)

    2010-01-01

    ... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Selection and appointment. 302.401 Section 302.401 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS EMPLOYMENT IN THE EXCEPTED SERVICE Selection and Appointment; Reappointment; and Qualifications for Promotion...

  15. 39 CFR 5.1 - Establishment and appointment.

    Science.gov (United States)

    2010-07-01

    ... 39 Postal Service 1 2010-07-01 2010-07-01 false Establishment and appointment. 5.1 Section 5.1 Postal Service UNITED STATES POSTAL SERVICE THE BOARD OF GOVERNORS OF THE U.S. POSTAL SERVICE COMMITTEES (ARTICLE V) § 5.1 Establishment and appointment. From time to time the Board may establish by resolution...

  16. Multi-agent Pareto appointment exchanging in hospital patient scheduling

    NARCIS (Netherlands)

    I.B. Vermeulen (Ivan); S.M. Bohte (Sander); D.J.A. Somefun (Koye); J.A. La Poutré (Han)

    2007-01-01

    htmlabstractWe present a dynamic and distributed approach to the hospital patient scheduling problem, in which patients can have multiple appointments that have to be scheduled to different resources. To efficiently solve this problem we develop a multi-agent Pareto-improvement appointment

  17. Decentralized Online Scheduling of Combination-Appointments in Hospitals

    NARCIS (Netherlands)

    I.B. Vermeulen (Ivan); S.M. Bohte (Sander); S.G. Elkhuizen; P.J.M. Bakker; J.A. La Poutré (Han); S. Raaijmakers; J. Rintanen; B. Nebel; J.C. Beck

    2008-01-01

    htmlabstractWe consider the online problem of scheduling combination appointments for outpatients. Scheduling multiple appointments on a single day is high on the list of outpatient preferences. It is hard to achieve for two reasons: first, due to the typical distributed authority in hospitals,

  18. 29 CFR 0.737-2 - Appointment of alternate officials.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 1 2010-07-01 2010-07-01 true Appointment of alternate officials. 0.737-2 Section 0.737-2 Labor Office of the Secretary of Labor ETHICS AND CONDUCT OF DEPARTMENT OF LABOR EMPLOYEES Post Employment Conflict of Interest § 0.737-2 Appointment of alternate officials. Notwithstanding any other...

  19. 29 CFR 0.737-5 - Appointment of Examiner.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 1 2010-07-01 2010-07-01 true Appointment of Examiner. 0.737-5 Section 0.737-5 Labor Office of the Secretary of Labor ETHICS AND CONDUCT OF DEPARTMENT OF LABOR EMPLOYEES Post Employment Conflict of Interest § 0.737-5 Appointment of Examiner. Whenever a notice of alleged violation has been...

  20. 45 CFR 1603.4 - Procedure for appointment of council.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 4 2010-10-01 2010-10-01 false Procedure for appointment of council. 1603.4 Section 1603.4 Public Welfare Regulations Relating to Public Welfare (Continued) LEGAL SERVICES CORPORATION STATE ADVISORY COUNCILS § 1603.4 Procedure for appointment of council. At the formal request of...

  1. Approaches taken by South African advertisers to select and appoint ...

    African Journals Online (AJOL)

    Approaches taken by South African advertisers to select and appoint advertising agencies. 3 research considered industry norms and practices, buying behaviour within client firms, and a broader range of environmental and social forces affecting client–agency appointment and relations. In this study, we therefore attempt ...

  2. Role for voltage gated calcium channels in calcitonin gene-related peptide release in the rat trigeminovascular system

    DEFF Research Database (Denmark)

    Amrutkar, D V; Ploug, K B; Olesen, J

    2011-01-01

    Clinical and genetic studies have suggested a role for voltage gated calcium channels (VGCCs) in the pathogenesis of migraine. Release of calcitonin gene-related peptide (CGRP) from trigeminal neurons has also been implicated in migraine. The VGCCs are located presynaptically on neurons and are i......Clinical and genetic studies have suggested a role for voltage gated calcium channels (VGCCs) in the pathogenesis of migraine. Release of calcitonin gene-related peptide (CGRP) from trigeminal neurons has also been implicated in migraine. The VGCCs are located presynaptically on neurons...... and are involved in the release of these peptides to different stimuli. We have examined the presence and importance of VGCCs in controlling the CGRP release from rat dura mater, freshly isolated trigeminal ganglion (TG) and trigeminal nucleus caudalis (TNC). Each of the four VGCCs, P/Q-, N-, and L- and T...... the potassium induced CGRP release. In the absence of calcium ions (Ca2+) and in the presence of a cocktail of blockers, the stimulated CGRP release from dura mater was reduced almost to the same level as basal CGRP release. In the TG ¿-conotoxin GVIA inhibited the potassium induced CGRP release significantly...

  3. Role for voltage gated calcium channels in calcitonin gene-related peptide release in the rat trigeminovascular system

    DEFF Research Database (Denmark)

    Amrutkar, D V; Ploug, K B; Olesen, J

    2011-01-01

    Clinical and genetic studies have suggested a role for voltage gated calcium channels (VGCCs) in the pathogenesis of migraine. Release of calcitonin gene-related peptide (CGRP) from trigeminal neurons has also been implicated in migraine. The VGCCs are located presynaptically on neurons and are i......Clinical and genetic studies have suggested a role for voltage gated calcium channels (VGCCs) in the pathogenesis of migraine. Release of calcitonin gene-related peptide (CGRP) from trigeminal neurons has also been implicated in migraine. The VGCCs are located presynaptically on neurons...... and are involved in the release of these peptides to different stimuli. We have examined the presence and importance of VGCCs in controlling the CGRP release from rat dura mater, freshly isolated trigeminal ganglion (TG) and trigeminal nucleus caudalis (TNC). Each of the four VGCCs, P/Q-, N-, and L- and T...... the potassium induced CGRP release. In the absence of calcium ions (Ca2+) and in the presence of a cocktail of blockers, the stimulated CGRP release from dura mater was reduced almost to the same level as basal CGRP release. In the TG ω-conotoxin GVIA inhibited the potassium induced CGRP release significantly...

  4. The Impact of Health Care Appointment Non-Adherence on Graft Outcomes in Kidney Transplantation.

    Science.gov (United States)

    Taber, David J; Fleming, James N; Fominaya, Cory E; Gebregziabher, Mulugeta; Hunt, Kelly J; Srinivas, Titte R; Baliga, Prabhakar K; McGillicuddy, John W; Egede, Leonard E

    2017-01-01

    Non-adherence to medication is a well-studied and known cause of late allograft loss, but it is difficult to measure and prospectively monitor. The aim of this study was to assess if appointment non-adherence was correlated with medication non-adherence and a predictor of graft outcomes. This was a longitudinal cohort study that used the National United States Renal Data System and veterans affairs health records data with time-to-event analyses conducted to assess the impact on graft and patient survival. The number of transplants that were included in the analysis was 4,646 (3,656 with complete records); 14.6% of patients had an appointment no show rate of ≥12% (non-adherence). Appointment and medication non-adherence were highly correlated and both were significant independent predictors of outcomes. Those with appointment non-adherence had 1.5 times the risk of acute rejection (22.0 vs. 14.7%, p adherence; those with appointment and medication non-adherence were at very high risk of graft loss (aHR 4.18, 95% CI 3.39-5.15, p adherence (aHR 1.39, 95% CI 0.97-2.01, p = 0.0766) or only medication non-adherence (aHR 2.44, 95% CI 2.11-2.81, p adherence to health care appointments is a significant and independent risk factor for graft loss. © 2016 S. Karger AG, Basel.

  5. Integration of a real-time tumor monitoring system into gated proton spot-scanning beam therapy: An initial phantom study using patient tumor trajectory data

    Energy Technology Data Exchange (ETDEWEB)

    Matsuura, Taeko; Miyamoto, Naoki; Takao, Seishin; Nihongi, Hideaki; Toramatsu, Chie; Sutherland, Kenneth; Suzuki, Ryusuke; Ishikawa, Masayori; Maeda, Kenichiro [Department of Medical Physics, Hokkaido University Graduate School of Medicine, Sapporo, Hokkaido, 060-8638 (Japan); Shimizu, Shinichi; Kinoshita, Rumiko; Umegaki, Kikuo; Shirato, Hiroki [Department of Radiation Medicine, Hokkaido University Graduate School of Medicine, Sapporo, Hokkaido, 060-8648 (Japan); Fujii, Yusuke; Umezawa, Masumi [Hitachi, Ltd., Hitachi Research Laboratory, 7-2-1 Omika-cho, Hitachi-shi, Ibaraki 319-1221 (Japan)

    2013-07-15

    Purpose: In spot-scanning proton therapy, the interplay effect between tumor motion and beam delivery leads to deterioration of the dose distribution. To mitigate the impact of tumor motion, gating in combination with repainting is one of the most promising methods that have been proposed. This study focused on a synchrotron-based spot-scanning proton therapy system integrated with real-time tumor monitoring. The authors investigated the effectiveness of gating in terms of both the delivered dose distribution and irradiation time by conducting simulations with patients' motion data. The clinically acceptable range of adjustable irradiation control parameters was explored. Also, the relation between the dose error and the characteristics of tumor motion was investigated.Methods: A simulation study was performed using a water phantom. A gated proton beam was irradiated to a clinical target volume (CTV) of 5 Multiplication-Sign 5 Multiplication-Sign 5 cm{sup 3}, in synchronization with lung cancer patients' tumor trajectory data. With varying parameters of gate width, spot spacing, and delivered dose per spot at one time, both dose uniformity and irradiation time were calculated for 397 tumor trajectory data from 78 patients. In addition, the authors placed an energy absorber upstream of the phantom and varied the thickness to examine the effect of changing the size of the Bragg peak and the number of required energy layers. The parameters with which 95% of the tumor trajectory data fulfill our defined criteria were accepted. Next, correlation coefficients were calculated between the maximum dose error and the tumor motion characteristics that were extracted from the tumor trajectory data.Results: With the assumed CTV, the largest percentage of the data fulfilled the criteria when the gate width was {+-}2 mm. Larger spot spacing was preferred because it increased the number of paintings. With a prescribed dose of 2 Gy, it was difficult to fulfill the

  6. The Problem of Missed Mental Health Care Appointments.

    Science.gov (United States)

    Miller, Marilyn J; Ambrose, Donna M

    2016-12-20

    Missed appointments are a problem in all types of outpatient clinics including those providing mental health care. A review of literature was conducted to explore the problem of missed appointments in mental health and identify methods that have been used to improve attendance. Study results demonstrate that patients miss appointments for many reasons. Common reasons for missed appointments in the articles reviewed were the interval between scheduling and appointment day, forgetting, being discharged against medical advice, and problems with substance abuse. Effective in reducing no shows was contact via phone, mail, or text messaging. No articles were found related to the use of positive reinforcement in reducing no shows, which is an area to consider for further research. Clinicians may identify techniques from this review applicable to their particular clinical setting to improve clinic attendance.

  7. Between the Cup and the Lip: Missed Dental Appointments.

    Science.gov (United States)

    Tandon, Sandeep; Duhan, Reena; Sharma, Meenakshi; Vasudeva, Suraj

    2016-05-01

    Missed appointments are an issue which have been very commonly noticed but overlooked in Indian dental society. Almost every dentist, general or specialized, private or public, has faced this problem in routine practice but very less research has been conducted on this issue in Asian countries. The aim of this study was to determine the frequency and distribution of missed dental appointments among children and the reasons behind the non-attendance in department of paediatric and preventive dentistry. Patients under 15 years of age who reported during the period March through August 2014 were included in this study. Attendance data and demographical data for patients was obtained from patient records and the hospital database. The type of treatment patients were to receive was gathered from the appointment diaries of staff, postgraduate students and undergraduates. A structured questionnaire regarding the most frequent reasons given by patients for not attending the scheduled appointment was also prepared. The data were analysed using descriptive analysis. Of the total 2294 patients 886 patients failed to come on their scheduled appointment. Percentage of patients who missed their appointments was 38.6%. A 38.2% of them required primary teeth pulp therapy. No significant differences was found between genders regarding the prevalence of missed dental appointments. Only 40% dentist witnessed that the most common reason for their patients to miss dental appointment was "no leave from school". Illness was the second frequent excuse heard by dentists (5/20= 25%) from their patients and attendants. Missed dental appointment was found to be a common issue in paediatric age group. Counseling and motivation is required to be done at first dental visit to reduce the chances of missed appointment.

  8. Pathways to care and psychological problems of general practice patients in a "gate keeper" and an "open access" health care system: a comparison of Germany and the Netherlands.

    Science.gov (United States)

    Linden, M; Gothe, H; Ormel, J

    2003-12-01

    The comparison of different health care systems is one way to give empirical evidence to health care reform and policy. The differences between health care systems in which general practitioners serve as gate keepers in comparison to systems in which patients are free to contact every physician and specialist they like are a question of high interest. This study compares the Netherlands and Germany, two countries with very similar political, social, and health system structures, but different types of access to the health care system. While Germany offers unconstrained access to specialist ambulatory care, the Netherlands restricts health care utilization by giving primary care a 'gate keeper' function not allowing patients direct access to specialist care. Data from the WHO international collaborative study on psychological problems in general health care (Ustün and Sartorius 1995) were analysed with respect to pathways to care, treatment, and health status. In an initial cross-sectional assessment, in 3-month and 12-month follow-ups, contacts to physicians or hospital admission have also been monitored. There were only marginal differences between the Dutch and the German sample in the sociodemographic characteristics as well as in the diagnostic status with respect to mental disorders. In the Netherlands, 95.5%, and in Germany, 68.8% of the patients presented their 'reason for visit' for the first time to any physician at this index contact with a general practitioner. During the following 3 months, 24% of the Dutch patients, but 60.2% of the German patients, additionally contacted other physicians ( P Germany vs. 25.4 0/00 in the Netherlands ( P system reduce the number of contacts to other physicians and the intensity of treatment, while at the same time the rate of hospital admissions is increased.

  9. Edge-on gating effect in molecular wires.

    Science.gov (United States)

    Lo, Wai-Yip; Bi, Wuguo; Li, Lianwei; Jung, In Hwan; Yu, Luping

    2015-02-11

    This work demonstrates edge-on chemical gating effect in molecular wires utilizing the pyridinoparacyclophane (PC) moiety as the gate. Different substituents with varied electronic demands are attached to the gate to simulate the effect of varying gating voltages similar to that in field-effect transistor (FET). It was observed that the orbital energy level and charge carrier's tunneling barriers can be tuned by changing the gating group from strong electron acceptors to strong electron donors. The single molecule conductance and current-voltage characteristics of this molecular system are truly similar to those expected for an actual single molecular transistor.

  10. Stay vane and wicket gate relationship study

    Energy Technology Data Exchange (ETDEWEB)

    None, None

    2005-01-19

    This report evaluates potential environmental and performance gains that can be achieved in a Kaplan turbine through non-structural modifications to stay vane and wicket gate assemblies. This summary is based primarily on data and conclusions drawn from models and studies of Lower Granite Dam. Based on this investigation, the study recommends (1) a proof of concept at Lower Granite Dam to establish predicted improvements for the existing turbine and to further refine the stay vane wicket gate designs for fish passage; and (2) consideration of the stay vane wicket gate systems in any future turbine rehabilitation studies.

  11. Optimization design of a gating system for sand casting aluminium A356 using a Taguchi method and multi-objective culture-based QPSO algorithm

    Directory of Open Access Journals (Sweden)

    Wen-Jong Chen

    2016-04-01

    Full Text Available This article combined Taguchi method and analysis of variance with the culture-based quantum-behaved particle swarm optimization to determine the optimal models of gating system for aluminium (Al A356 sand casting part. First, the Taguchi method and analysis of variance were, respectively, applied to establish an L27(38 orthogonal array and determine significant process parameters, including riser diameter, pouring temperature, pouring speed, riser position and gating diameter. Subsequently, a response surface methodology was used to construct a second-order regression model, including filling time, solidification time and oxide ratio. Finally, the culture-based quantum-behaved particle swarm optimization was used to determine the multi-objective Pareto optimal solutions and identify corresponding process conditions. The results showed that the proposed method, compared with initial casting model, enabled reducing the filling time, solidification time and oxide ratio by 68.14%, 50.56% and 20.20%, respectively. A confirmation experiment was verified to be able to effectively reduce the defect of casting and improve the casting quality.

  12. Faculty Members’ Views on Academic Promotion and Appointment Process

    Directory of Open Access Journals (Sweden)

    Engin DEMİR

    2017-04-01

    Full Text Available Despite the changes made related to academic promotion and appointment over the years in Turkey, there have been two main criteria: academic publications after PhD and foreign language proficiency. It commonly known that faculty members come across several problems during the process of attaining the title of associate professorship and these problems affect the academic environment in several ways. The purpose of this study is to reveal the faculty members’ views on the academic promotion in postdoctoral process and provide further suggestions.. Data were gathered through a semi-structured interview form including 10 items prepared by the researcher and analyzed through content analysis. In addition, a criterion table comprised of 25 items was applied to the participants before the interview. These criteria were determined by the InteruniversityBoard of Turkey and other universities. 18 faculty members marked the criteria they consider essential. Participants consisted of faculty members from science, social and medical fields. Results of the study revealed that faculty members considered associate professorship exam and foreign language exam necessary. According to the faculty members, the criteria related to publishing international articles and lecturing at undergraduate and graduate levels were especially very important among all criteria and the current system had a determinant role in the faculty members’ behaviors and academic publications. Faculty members stated that foreign language exam did not measure language proficiency accurately ; academic positions were not assigned fairly; there were some problems about the quality of academic publications, ethics and being a scientist. Similarly, they clearly stated that the society did not rely on scientists. The results gained in the study corroborate the need to review the academic promotion and appointment process. An increase in the number of such studies that examine faculty members

  13. The Preoptic Area and the RFamide-Related Peptide Neuronal System Gate Seasonal Changes in Chemosensory Processing

    DEFF Research Database (Denmark)

    Jennings, Kimberly J; Chasles, Manon; Cho, Hweyryoung

    2017-01-01

    Males of many species rely on chemosensory information for social communication. In male Syrian hamsters (Mesocricetus auratus), as in many species, female chemosignals potently stimulate sexual behavior and a concurrent, rapid increase in circulating luteinizing hormone (LH) and testosterone (T......). However, under winter-like, short-day (SD) photoperiods, when Syrian hamsters are reproductively quiescent, these same female chemosignals fail to elicit behavioral or hormonal responses, even after T replacement. It is currently unknown where in the brain chemosensory processing is gated in a seasonally...... T concentrations. Adult male Syrian hamsters were housed under either long-day (LD) (reproductively active) or SD (reproductively inactive) photoperiods with half of the SD animals receiving T replacement. Animals were exposed to either female hamster vaginal secretions (FHVSs) diluted in mineral...

  14. Frequency-resolved optical gating system with a tellurium crystal for characterizing free-electron lasers in the wavelength range of 10-30 μm

    International Nuclear Information System (INIS)

    Iijima, Hokuto; Nagai, Ryoji; Nishimori, Nobuyuki; Hajima, Ryoichi; Minehara, Eisuke J.

    2009-01-01

    A second-harmonic generation frequency-resolved optical gating (SHG-FROG) system has been developed for the complete characterization of laser pulses in the wavelength range of 10-30 μm. A tellurium crystal is used so that spectrally resolved autocorrelation signals with a good signal-to-noise ratio are obtained. Pulses (wavelength ∼22 μm) generated from a free-electron laser are measured by the SHG-FROG system. The SHG intensity profile and the spectrum obtained by FROG measurements are well consistent with those of independent measurements of the pulse length and spectrum. The pulse duration and spectral width determined from the FROG trace are 0.6 ps and 5.2 THz at full width half maximum, respectively.

  15. Predicting appointment misses in hospitals using data analytics

    Science.gov (United States)

    Karpagam, Sylvia; Ma, Nang Laik

    2017-01-01

    Background There is growing attention over the last few years about non-attendance in hospitals and its clinical and economic consequences. There have been several studies documenting the various aspects of non-attendance in hospitals. Project Predicting Appoint Misses (PAM) was started with the intention of being able to predict the type of patients that would not come for appointments after making bookings. Methods Historic hospital appointment data merged with “distance from hospital” variable was used to run Logistic Regression, Support Vector Machine and Recursive Partitioning to decide the contributing variables to missed appointments. Results Variables that are “class”, “time”, “demographics” related have an effect on the target variable, however, prediction models may not perform effectively due to very subtle influence on the target variable. Previously assumed major contributors like “age”, “distance” did not have a major effect on the target variable. Conclusions With the given data it will be very difficult to make any moderate/strong prediction of the Appointment misses. That being said with the help of the cut off we are able to capture all of the “appointment misses” in addition to also capturing the actualized appointments. PMID:28567409

  16. Evaluation of alternatives for reducing the consumption of natural gas fuel at city-gates of Brazilian transport systems; Avaliacao das alternativas de reducao do consumo de gas natural combustivel nos pontos de entrega dos sistemas de transporte brasileiros

    Energy Technology Data Exchange (ETDEWEB)

    Santos, Almir B. [Agencia Nacional do Petroleo, Gas Natural e Biocombustiveis (ANP), Rio de Janeiro, RJ (Brazil); Augusto, Cristiane R.; Seidl, Peter R. [Universidade Federal do Rio de Janeiro (UFRJ), RJ (Brazil). Escola de Quimica; Goncalves, Raquel G. [UNISUAM - Centro Universitario Augusto Motta, Rio de Janeiro, RJ (Brazil)

    2008-07-01

    This work aims to identify actions that can be implemented to increase the energy efficiency of processes involved in the value chain of natural gas, specifically in the process of heating in existing city-gates of transporting natural gas Brazilians plants. The goal is increase supply of gas in Brazil. The main function of city-gates is to deliver the natural gas in contract terms (flow, pressure, temperature and quality). The main issue related to the consumption of natural gas fuel in city-gates is related to the operation (set-up and control) of natural gas combustion, in other words, depends on how the heating system is adjusted dynamically to burn, efficiently, the exact amount of gas required by this system, depending on temperature, pressure, temperature, quality and flow of natural gas at the 'city-gates'. The main objective of this work is to present a study on alternatives at design, set-up and control of natural gas city-gates (transport) in Brazil, aiming to increase the energy efficiency of this facility, and thus contributing to the growth in supply of natural gas available to the market. (author)

  17. Double-gated spectral snapshots for biomolecular fluorescence

    International Nuclear Information System (INIS)

    Nakamura, Ryosuke; Hamada, Norio; Ichida, Hideki; Tokunaga, Fumio; Kanematsu, Yasuo

    2007-01-01

    A versatile method to take femtosecond spectral snapshots of fluorescence has been developed based on a double gating technique in the combination of an optical Kerr gate and an image intensifier as an electrically driven gate set in front of a charge-coupled device detector. The application of a conventional optical-Kerr-gate method is limited to molecules with the short fluorescence lifetime up to a few hundred picoseconds, because long-lifetime fluorescence itself behaves as a source of the background signal due to insufficiency of the extinction ratio of polarizers employed for the Kerr gate. By using the image intensifier with the gate time of 200 ps, we have successfully suppressed the background signal and overcome the application limit of optical-Kerr-gate method. The system performance has been demonstrated by measuring time-resolved fluorescence spectra for laser dye solution and the riboflavin solution as a typical sample of biomolecule

  18. Entanglement and Quantum Logical Gates. Part I.

    Science.gov (United States)

    Freytes, H.; Giuntini, R.; Leporini, R.; Sergioli, G.

    2015-12-01

    Is it possible to give a logical characterization of entanglement and of entanglement-measures in terms of the probabilistic behavior of some gates? This question admits different (positive or negative) answers in the case of different systems of gates and in the case of different classes of density operators. In the first part of this article we investigate possible relations between entanglement-measures and the probabilistic behavior of quantum computational conjunctions.

  19. The impact of short message service text messages sent as appointment reminders to patients' cell phones at outpatient clinics in São Paulo, Brazil.

    Science.gov (United States)

    da Costa, Thiago Martini; Salomão, Paulo Lísias; Martha, Amilton Souza; Pisa, Ivan Torres; Sigulem, Daniel

    2010-01-01

    Nonattendance for appointments remains a challenge to health care managers and providers. The objective of this article is to present the results of a study on the impact of appointment reminders sent as short message service text messages to patients' cell phones on nonattendance rates at outpatient clinics in São Paulo, Brazil. Data were collected on scheduled appointments in four medical clinics using Clinic Manager or Clinic Web systems that can send automated messages to patients. Data on appointment attendance were collected from these systems. More than 29,000 appointments were scheduled between July 1, 2007, and May 31, 2008, and for 7890 of them a text message reminder was sent to the patient's cell phone. The rates of nonattendance were compared between those who were sent and those who were not sent a text message as an appointment reminder. The nonattendance reduction rates for appointments at the four outpatient clinics studied were 0.82% (p= .590), 3.55% (p= .009), 5.75% (p= .022), and 14.49% (p= cell phones is an effective strategy to reduce nonattendance rates. When patients attend their appointments, the facility providing care and the patients receiving uninterrupted care benefit. Copyright (c) 2009. Published by Elsevier Ireland Ltd.

  20. An investigation into why patients do not attend for out-patient radiology appointments

    International Nuclear Information System (INIS)

    Lyon, Rebecca; Reeves, Pauline J.

    2006-01-01

    Introduction: Patients who do not attend (DNA) for out-patient hospital appointments cause delays in the diagnosis and subsequent treatment of their own, and other patient's, illnesses, with potentially hazardous consequences. This also impacts upon waiting lists. Failure to attend is viewed as a specific type of non-compliance and social cognition theories have been applied to previous studies in an attempt to uncover the reasons why patients choose not to keep their appointments. Methods: A case-control study was conducted throughout the X-ray departments of a District General type of NHS Trust, using telephone interview questionnaires based on the Health Belief Model, in an attempt to identify any significant differences between attenders and non-attenders, so that likely non-attenders could be targeted. Results: Principal reasons for non-attendance were that the patient forgot or that they did not receive their appointment. The results differed from previous research, in that specific health beliefs were not the primary reasons for non-attendance. Departments that gave patients the opportunity to arrange their appointments for a mutually convenient time had exceptionally low DNA rates, as did those which had rigorous confirmation systems in place

  1. Gated community Na Krutci

    Czech Academy of Sciences Publication Activity Database

    Hnídková, Vendula

    2012-01-01

    Roč. 91, č. 12 (2012), s. 750-752 ISSN 0042-4544 Institutional support: RVO:68378033 Keywords : Gated community * Czech contemporary architecture * Kuba Pilař Subject RIV: AL - Art, Architecture , Cultural Heritage

  2. Probing Dense Sprays with Gated, Picosecond, Digital Particle Field Holography

    Directory of Open Access Journals (Sweden)

    James Trolinger

    2011-12-01

    Full Text Available This paper describes work that demonstrated the feasibility of producing a gated digital holography system that is capable of producing high-resolution images of three-dimensional particle and structure details deep within dense particle fields of a spray. We developed a gated picosecond digital holocamera, using optical Kerr cell gating, to demonstrate features of gated digital holography that make it an exceptional candidate for this application. The Kerr cell gate shuttered the camera after the initial burst of ballistic and snake photons had been recorded, suppressing longer path, multiple scattered illumination. By starting with a CW laser without gating and then incorporating a picosecond laser and an optical Kerr gate, we were able to assess the imaging quality of the gated holograms, and determine improvement gained by gating. We produced high quality images of 50–200 μm diameter particles, hairs and USAF resolution charts from digital holograms recorded through turbid media where more than 98% of the light was scattered from the field. The system can gate pulses as short as 3 mm in pathlength (10 ps, enabling image-improving features of the system. The experiments lead us to the conclusion that this method has an excellent capability as a diagnostics tool in dense spray combustion research.

  3. Reversible gates and circuits descriptions

    Science.gov (United States)

    Gracki, Krzystof

    2017-08-01

    This paper presents basic methods of reversible circuit description. To design reversible circuit a set of gates has to be chosen. Most popular libraries are composed of three types of gates so called CNT gates (Control, NOT and Toffoli). The gate indexing method presented in this paper is based on the CNT gates set. It introduces a uniform indexing of the gates used during synthesis process of reversible circuits. The paper is organized as follows. Section 1 recalls basic concepts of reversible logic. In Section 2 and 3 a graphical representation of the reversible gates and circuits is described. Section 4 describes proposed uniform NCT gates indexing. The presented gate indexing method provides gate numbering scheme independent of lines number of the designed circuit. The solution for a circuit consisting of smaller number of lines is a subset of solution for a larger circuit.

  4. Advanced insulated gate bipolar transistor gate drive

    Science.gov (United States)

    Short, James Evans [Monongahela, PA; West, Shawn Michael [West Mifflin, PA; Fabean, Robert J [Donora, PA

    2009-08-04

    A gate drive for an insulated gate bipolar transistor (IGBT) includes a control and protection module coupled to a collector terminal of the IGBT, an optical communications module coupled to the control and protection module, a power supply module coupled to the control and protection module and an output power stage module with inputs coupled to the power supply module and the control and protection module, and outputs coupled to a gate terminal and an emitter terminal of the IGBT. The optical communications module is configured to send control signals to the control and protection module. The power supply module is configured to distribute inputted power to the control and protection module. The control and protection module outputs on/off, soft turn-off and/or soft turn-on signals to the output power stage module, which, in turn, supplies a current based on the signal(s) from the control and protection module for charging or discharging an input capacitance of the IGBT.

  5. Talking with Your Doctor: Make the Most of Your Appointment

    Science.gov (United States)

    ... this issue Talking With Your Doctor Make the Most of Your Appointment Send us your comments Patients ... a trusted source. Federal agencies are among the most reliable sources of online health information. Many health ...

  6. 78 FR 24749 - Health Information Technology Policy Committee Appointment

    Science.gov (United States)

    2013-04-26

    ... GOVERNMENT ACCOUNTABILITY OFFICE Health Information Technology Policy Committee Appointment AGENCY... Recovery and Reinvestment Act of 2009 (ARRA) established the Health Information Technology Policy Committee to make recommendations on the implementation of a nationwide health information technology...

  7. Introduction of audio gating to further reduce organ motion in breathing synchronized radiotherapy

    International Nuclear Information System (INIS)

    Kubo, H. Dale; Wang Lili

    2002-01-01

    With breathing synchronized radiotherapy (BSRT), a voltage signal derived from an organ displacement detector is usually displayed on the vertical axis whereas the elapsed time is shown on the horizontal axis. The voltage gate window is set on the breathing voltage signal. Whenever the breathing signal falls between the two gate levels, a gate pulse is produced to enable the treatment machine. In this paper a new gating mechanism, audio (or time-sequence) gating, is introduced and is integrated into the existing voltage gating system. The audio gating takes advantage of the repetitive nature of the breathing signal when repetitive audio instruction is given to the patient. The audio gating is aimed at removing the regions of sharp rises and falls in the breathing signal that cannot be removed by the voltage gating. When the breathing signal falls between voltage gate levels as well as between audio-gate levels, the voltage- and audio-gated radiotherapy (ART) system will generate an AND gate pulse. When this gate pulse is received by a linear accelerator, the linear accelerator becomes 'enabled' for beam delivery and will deliver the beam when all other interlocks are removed. This paper describes a new gating mechanism and a method of recording beam-on signal, both of which are, configured into a laptop computer. The paper also presents evidence of some clinical advantages achieved with the ART system

  8. Comparison of Traditional and Open-Access Appointment Scheduling for Exponentially Distributed Service Time

    Directory of Open Access Journals (Sweden)

    Chongjun Yan

    2015-01-01

    Full Text Available This paper compares the performance measures of traditional appointment scheduling (AS with those of an open-access appointment scheduling (OA-AS system with exponentially distributed service time. A queueing model is formulated for the traditional AS system with no-show probability. The OA-AS models assume that all patients who call before the session begins will show up for the appointment on time. Two types of OA-AS systems are considered: with a same-session policy and with a same-or-next-session policy. Numerical results indicate that the superiority of OA-AS systems is not as obvious as those under deterministic scenarios. The same-session system has a threshold of relative waiting cost, after which the traditional system always has higher total costs, and the same-or-next-session system is always preferable, except when the no-show probability or the weight of patients’ waiting is low. It is concluded that open-access policies can be viewed as alternative approaches to mitigate the negative effects of no-show patients.

  9. Interventions to reduce wait times for primary care appointments: a systematic review.

    Science.gov (United States)

    Ansell, Dominique; Crispo, James A G; Simard, Benjamin; Bjerre, Lise M

    2017-04-20

    Accessibility and availability are important characteristics of efficient and effective primary healthcare systems. Currently, timely access to a family physician is a concern in Canada. Adverse outcomes are associated with longer wait times for primary care appointments and often leave individuals to rely on urgent care. When wait times for appointments are too long patients may experience worse health outcomes and are often left to use emergency department resources. The primary objective of our study was to systematically review the literature to identify interventions designed to reduce wait times for primary care appointments. Secondary objectives were to assess patient satisfaction and reduction of no-show rates. We searched multiple databases, including: Medline via Ovid SP (1947 to present), Embase (from 1980 to present), PsychINFO (from 1806 to present), Cochrane Central Register of Controlled Trials (CENTRAL; all dates), Cumulative Index to Nursing and Allied Health (CINAHL; 1937 to present), and Pubmed (all dates) to identify studies that reported outcomes associated with interventions designed to reduce wait times for primary care appointments. Two independent reviewers assessed all identified studies for inclusion using pre-defined inclusion/exclusion criteria and a multi-level screening approach. Our study methods were guided by the Cochrane Handbook for Systematic Reviews of Interventions. Our search identified 3,960 articles that were eligible for inclusion, eleven of which satisfied all inclusion/exclusion criteria. Data abstraction of included studies revealed that open access scheduling is the most commonly used intervention to reduce wait times for primary care appointments. Additionally, included studies demonstrated that dedicated telephone calls for follow-up consultation, presence of nurse practitioners on staff, nurse and general practitioner triage, and email consultations were effective at reducing wait times. To our knowledge, this is

  10. EXTENSION EDUCATION SYMPOSIUM: Getting the most out of your extension appointment and still having a life.

    Science.gov (United States)

    Powers, W; Cockett, N; Lardy, G

    2017-04-01

    Managing the demands of an academic appointment in extension can be a challenging task. Demands from constituent groups, expectations of supervisors, and rigors of promotion and tenure processes can create pressures that young faculty did not expect. Throw in spousal and family duties and you have created a situation that many will find hard to navigate. However, there are ways to cope and, even better news, there are ways to excel in meeting the demands of an academic appointment and enjoying life. Because many new extension faculty members do not have prior experience in extension, best practices in documenting programs and extension scholarship over the pretenure period are provided in this paper. Appointments that include both research and extension are quite common at many land grant universities. The advantages of joint appointments are numerous and include the fact that more and more grant agencies are seeking integrated research, teaching, and/or extension projects. However, the time demands of joint appointments can be challenging. Joint appointments can be designed to help faculty members conduct important translational research and have it be applied in a production setting. By seeking commonalities in research and extension efforts, joint appointments can be very synergistic. Development of highly successful programs requires planning on the front end with an emphasis on an in-depth needs assessment to determine stakeholder needs for both research and extension. Impact assessment should be part of this planning effort. Performing as a successful extension faculty member while maintaining relationships outside of work is challenging and requires deliberate effort on the part of employees and supervisors to realize there is more to life than work. Some authors have referred to this as work-life balance, but it may be more helpful to think of it as work-life effectiveness. To do this, one needs to 1) define what success looks like, 2) set boundaries and

  11. Evaluation of the capacity to appoint a healthcare proxy.

    Science.gov (United States)

    Moye, Jennifer; Sabatino, Charles P; Weintraub Brendel, Rebecca

    2013-04-01

    The appointment of a healthcare proxy is the most common way through which patients appoint a surrogate decision maker in anticipation of a future time in which they may lack the ability to make medical decisions themselves. In some situations, when a patient has not previously appointed a surrogate decision maker through an advance directive, the healthcare team may ask whether the patient, although lacking the capacity to make a healthcare decision, might still have the capacity to appoint a healthcare proxy. In this article the authors summarize the existing, albeit limited, legal and empirical basis for this capacity and propose a model for assessing capacity to appoint a healthcare proxy that incorporates clinical factors in the context of the risks and benefits specific to surrogate appointment under the law. In particular, it is important to weigh patients' understanding and choice within the context of the risks and benefits of the medical and interpersonal factors. Questions to guide capacity assessment are provided for clinical use and refinement through future research. Copyright © 2013 American Association for Geriatric Psychiatry. All rights reserved.

  12. Four-dimensional computed tomography based respiratory-gated radiotherapy with respiratory guidance system: analysis of respiratory signals and dosimetric comparison.

    Science.gov (United States)

    Lee, Jung Ae; Kim, Chul Yong; Yang, Dae Sik; Yoon, Won Sup; Park, Young Je; Lee, Suk; Kim, Young Bum

    2014-01-01

    To investigate the effectiveness of respiratory guidance system in 4-dimensional computed tomography (4 DCT) based respiratory-gated radiation therapy (RGRT) by comparing respiratory signals and dosimetric analysis of treatment plans. The respiratory amplitude and period of the free, the audio device-guided, and the complex system-guided breathing were evaluated in eleven patients with lung or liver cancers. The dosimetric parameters were assessed by comparing free breathing CT plan and 4 DCT-based 30-70% maximal intensity projection (MIP) plan. The use of complex system-guided breathing showed significantly less variation in respiratory amplitude and period compared to the free or audio-guided breathing regarding the root mean square errors (RMSE) of full inspiration (P = 0.031), full expiration (P = 0.007), and period (P = 0.007). The dosimetric parameters including V(5 Gy), V(10 Gy), V(20 Gy), V(30 Gy), V(40 Gy), and V(50 Gy) of normal liver or lung in 4 DCT MIP plan were superior over free breathing CT plan. The reproducibility and regularity of respiratory amplitude and period were significantly improved with the complex system-guided breathing compared to the free or the audio-guided breathing. In addition, the treatment plan based on the 4D CT-based MIP images acquired with the complex system guided breathing showed better normal tissue sparing than that on the free breathing CT.

  13. Stability of Quantum Loops and Exchange Operations in the Construction of Quantum Computation Gates

    International Nuclear Information System (INIS)

    Bermúdez, D; Delgado, F

    2017-01-01

    Quantum information and quantum computation is a rapidly emergent field where quantum systems and their applications play a central role. In the gate version of quantum computation, the construction of universal quantum gates to manipulate quantum information is currently an intensive arena for quantum engineering. Specific properties of systems should be able to reproduce such idealized gates imitating the classically inspired computational gates. Recently, for magnetic systems driven by the bipartite Heisenberg-Ising model a universal set of gates has been realized, an alternative easy design for the Boykin set but using the Bell states as grammar. Exact control can be then used to construct specific prescriptions to achieve those gates. Physical parameters impose a challenge in the gate control. This work analyzes, based on the worst case quantum fidelity, the associated instability for the proposed set of gates. An strong performance is found in those gates for the most of quantum states involved. (paper)

  14. Appointment keeping for medical review among patients with selected chronic diseases in an urban area of Uganda.

    Science.gov (United States)

    Kalyango, Joan Nakayaga; Hall, Maurice; Karamagi, Charles

    2014-01-01

    Proper management of chronic diseases is important for prevention of disease complications and yet some patients miss appointments for medical review thereby missing the opportunity for proper monitoring of their disease conditions. There is limited information on missed appointments among chronic disease patients in resource limited settings. This study aimed to determine the prevalence of missed appointments for medical review and associated factors among chronic disease patients in an urban area of Uganda. Patients or caregivers of children with chronic diseases were identified as they bought medicines from a community pharmacy. They were visited at home to access their medical documents and those whose chronic disease status was ascertained were enrolled. The data was collected using: questionnaires, review of medical documents, and in-depth interviews with chronic disease patients. The prevalence of missed appointments was 42% (95%CI = 35-49%). The factors associated with missed appointments were: monthly income ≤30US Dollars (OR = 2.56, CI = 1.25-5.26), affording less than half of prescribed drugs (OR = 3.92, CI = 1.64-9.40), not experiencing adverse events (OR = 2.66, CI = 1.26-5.61), not sure if treatment helps (OR = 2.84, CI = 1.047.77), not having a medicines administration schedule (OR = 6.77, CI = 2.11-21.68), and increasing number of drugs (OR = 0.72, CI = 0.53-0.98). Patients missed appointments mainly due to: financial and health system barriers, conflicting commitments with appointments, and perceptions of the disease condition. Patients should be supported with accessible and affordable health services.

  15. Cardiac gated ventilation

    Science.gov (United States)

    Hanson, C. William, III; Hoffman, Eric A.

    1995-05-01

    There are several theoretic advantages to synchronizing positive pressure breaths with the cardiac cycle, including the potential for improving distribution of pulmonary and myocardial blood flow and enhancing cardiac output. We evaluated the effects of synchronizing respiration to the cardiac cycle using a programmable ventilator and electron beam CT (EBCT) scanning. The hearts of anesthetized dogs were imaged during cardiac gated respiration with a 50msec scan aperture. Multislice, short axis, dynamic image data sets spanning the apex to base of the left ventricle were evaluated to determine the volume of the left ventricular chamber at end-diastole and end-systole during apnea, systolic and diastolic cardiac gating. We observed an increase in cardiac output of up to 30% with inspiration gated to the systolic phase of the cardiac cycle in a nonfailing model of the heart.

  16. Resource Allocation and Outpatient Appointment Scheduling Using Simulation Optimization

    Directory of Open Access Journals (Sweden)

    Carrie Ka Yuk Lin

    2017-01-01

    Full Text Available This paper studies the real-life problems of outpatient clinics having the multiple objectives of minimizing resource overtime, patient waiting time, and waiting area congestion. In the clinic, there are several patient classes, each of which follows different treatment procedure flow paths through a multiphase and multiserver queuing system with scarce staff and limited space. We incorporate the stochastic factors for the probabilities of the patients being diverted into different flow paths, patient punctuality, arrival times, procedure duration, and the number of accompanied visitors. We present a novel two-stage simulation-based heuristic algorithm to assess various tactical and operational decisions for optimizing the multiple objectives. In stage I, we search for a resource allocation plan, and in stage II, we determine a block appointment schedule by patient class and a service discipline for the daily operational level. We also explore the effects of the separate strategies and their integration to identify the best possible combination. The computational experiments are designed on the basis of data from a study of an ophthalmology clinic in a public hospital. Results show that our approach significantly mitigates the undesirable outcomes by integrating the strategies and increasing the resource flexibility at the bottleneck procedures without adding resources.

  17. Active gated imaging for automotive safety applications

    Science.gov (United States)

    Grauer, Yoav; Sonn, Ezri

    2015-03-01

    The paper presents the Active Gated Imaging System (AGIS), in relation to the automotive field. AGIS is based on a fast gated-camera equipped with a unique Gated-CMOS sensor, and a pulsed Illuminator, synchronized in the time domain to record images of a certain range of interest which are then processed by computer vision real-time algorithms. In recent years we have learned the system parameters which are most beneficial to night-time driving in terms of; field of view, illumination profile, resolution and processing power. AGIS provides also day-time imaging with additional capabilities, which enhances computer vision safety applications. AGIS provides an excellent candidate for camera-based Advanced Driver Assistance Systems (ADAS) and the path for autonomous driving, in the future, based on its outstanding low/high light-level, harsh weather conditions capabilities and 3D potential growth capabilities.

  18. Sequential Appointment Scheduling Considering Walk-In Patients

    Directory of Open Access Journals (Sweden)

    Chongjun Yan

    2014-01-01

    Full Text Available This paper develops a sequential appointment algorithm considering walk-in patients. In practice, the scheduler assigns an appointment time for each call-in patient before the call ends, and the appointment time cannot be changed once it is set. Each patient has a certain probability of being a no-show patient on the day of appointment. The objective is to determine the optimal booking number of patients and the optimal scheduling time for each patient to maximize the revenue of all the arriving patients minus the expenses of waiting time and overtime. Based on the assumption that the service time is exponentially distributed, this paper proves that the objective function is convex. A sufficient condition under which the profit function is unimodal is provided. The numerical results indicate that the proposed algorithm outperforms all the commonly used heuristics, lowering the instances of no-shows, and walk-in patients can improve the service efficiency and bring more profits to the clinic. It is also noted that the potential appointment is an effective alternative to mitigate no-show phenomenon.

  19. Bilevel Fuzzy Chance Constrained Hospital Outpatient Appointment Scheduling Model

    Directory of Open Access Journals (Sweden)

    Xiaoyang Zhou

    2016-01-01

    Full Text Available Hospital outpatient departments operate by selling fixed period appointments for different treatments. The challenge being faced is to improve profit by determining the mix of full time and part time doctors and allocating appointments (which involves scheduling a combination of doctors, patients, and treatments to a time period in a department optimally. In this paper, a bilevel fuzzy chance constrained model is developed to solve the hospital outpatient appointment scheduling problem based on revenue management. In the model, the hospital, the leader in the hierarchy, decides the mix of the hired full time and part time doctors to maximize the total profit; each department, the follower in the hierarchy, makes the decision of the appointment scheduling to maximize its own profit while simultaneously minimizing surplus capacity. Doctor wage and demand are considered as fuzzy variables to better describe the real-life situation. Then we use chance operator to handle the model with fuzzy parameters and equivalently transform the appointment scheduling model into a crisp model. Moreover, interactive algorithm based on satisfaction is employed to convert the bilevel programming into a single level programming, in order to make it solvable. Finally, the numerical experiments were executed to demonstrate the efficiency and effectiveness of the proposed approaches.

  20. Instant Oracle GoldenGate

    CERN Document Server

    Bruzzese, Tony

    2013-01-01

    Filled with practical, step-by-step instructions and clear explanations for the most important and useful tasks. Get the job done and learn as you go. A how-To book with practical recipes accompanied with rich screenshots for easy comprehension.This is a Packt Instant How-to guide, which provides concise and clear recipes for performing the core task of replication using Oracle GoldenGate.The book is aimed at DBAs from any of popular RDBMS systems such as Oracle, SQL Server, Teradata, Sybase, and so on. The level of detail provides quick applicability to beginners and a handy review for more a

  1. Gate-error analysis in simulations of quantum computers with transmon qubits

    Science.gov (United States)

    Willsch, D.; Nocon, M.; Jin, F.; De Raedt, H.; Michielsen, K.

    2017-12-01

    In the model of gate-based quantum computation, the qubits are controlled by a sequence of quantum gates. In superconducting qubit systems, these gates can be implemented by voltage pulses. The success of implementing a particular gate can be expressed by various metrics such as the average gate fidelity, the diamond distance, and the unitarity. We analyze these metrics of gate pulses for a system of two superconducting transmon qubits coupled by a resonator, a system inspired by the architecture of the IBM Quantum Experience. The metrics are obtained by numerical solution of the time-dependent Schrödinger equation of the transmon system. We find that the metrics reflect systematic errors that are most pronounced for echoed cross-resonance gates, but that none of the studied metrics can reliably predict the performance of a gate when used repeatedly in a quantum algorithm.

  2. One versus two appointment endodontic treatment on teeth with apical periodontitis

    Directory of Open Access Journals (Sweden)

    Juni Jekti Nugroho

    2016-06-01

    Full Text Available The microbiological purpose of endodontic treatment on tooth with apical periodontitis is reducing microbes to achieve periradicular tissue healing and prevent microbes recolonized. This is achieved by antimicrobial measures, including chemomechanical procedures and intracanal medication, with root canal obturation steps. One of the problem in endodontic is the planning consideration to treat with one or two visits. Does intra-appointment medication is an absolute measure to promote desinfection and treatment success. To provide a guideline about  one or two visit endodontic treatment decision making for dental professionals. Root canal system on tooth with apical periodontitis treated in two visit endodontic and calcium hydroxide as the intra-appointment medication achieved better microbiological status than the one treated in one visit endodontic.

  3. Gate valve performance prediction

    International Nuclear Information System (INIS)

    Harrison, D.H.; Damerell, P.S.; Wang, J.K.; Kalsi, M.S.; Wolfe, K.J.

    1994-01-01

    The Electric Power Research Institute is carrying out a program to improve the performance prediction methods for motor-operated valves. As part of this program, an analytical method to predict the stem thrust required to stroke a gate valve has been developed and has been assessed against data from gate valve tests. The method accounts for the loads applied to the disc by fluid flow and for the detailed mechanical interaction of the stem, disc, guides, and seats. To support development of the method, two separate-effects test programs were carried out. One test program determined friction coefficients for contacts between gate valve parts by using material specimens in controlled environments. The other test program investigated the interaction of the stem, disc, guides, and seat using a special fixture with full-sized gate valve parts. The method has been assessed against flow-loop and in-plant test data. These tests include valve sizes from 3 to 18 in. and cover a considerable range of flow, temperature, and differential pressure. Stem thrust predictions for the method bound measured results. In some cases, the bounding predictions are substantially higher than the stem loads required for valve operation, as a result of the bounding nature of the friction coefficients in the method

  4. Recentralization of local government chief administrative officers appointments in Uganda: Implications for downward accountability

    Directory of Open Access Journals (Sweden)

    Lazarus Nabaho

    2013-12-01

    Full Text Available The Uganda Constitution of 1995 spelt out the principle of decentralization by devolution. Accordingly, from 1995 to 2005, district local governments had a dejure mandate to hire and fire all categories of civil servants through their respective district service commissions (DSCs. Following the Constitutional amendment in September 2005, the right to hire and fire district chief administrative officers (CAOs reverted to central government. Critics of recentralization of CAO appointments contend that the shift in the policy and legislation for managing CAOs runs contrary to the principles of decentralization by devolution. This paper argues that recentralization of CAOs has confused reporting, reduced the autonomy of sub-national governments in civil service management, undermined accountability of CAOs to elected councils, and shifted the loyalty of CAOs from local governments with and for which they work to central government that appoints and deploys them. To deepen accountability in local governments, the paper advocates for decentralization of CAO appointments, but for participation of central government in recruitment of CAOs within the confines of a separate personnel system. It further calls for a rethinking of the current call by the 9th Parliament to recentralize human resource in health in local governments owing to accountability challenges of managing the civil service in sub-national governments under an integrated personnel system.

  5. The four-gate transistor

    Science.gov (United States)

    Mojarradi, M. M.; Cristoveanu, S.; Allibert, F.; France, G.; Blalock, B.; Durfrene, B.

    2002-01-01

    The four-gate transistor or G4-FET combines MOSFET and JFET principles in a single SOI device. Experimental results reveal that each gate can modulate the drain current. Numerical simulations are presented to clarify the mechanisms of operation. The new device shows enhanced functionality, due to the combinatorial action of the four gates, and opens rather revolutionary applications.

  6. Stanford, Duke, Rice,... and Gates?

    Science.gov (United States)

    Carey, Kevin

    2009-01-01

    This article presents an open letter to Bill Gates. In his letter, the author suggests that Bill Gates should build a brand-new university, a great 21st-century institution of higher learning. This university will be unlike anything the world has ever seen. He asks Bill Gates not to stop helping existing colleges create the higher-education system…

  7. [Principles of nutrition in patients with newly appointed stoma].

    Science.gov (United States)

    Pachocka, Lucyna Małgorzata; Urbanik, Anna

    2016-01-01

    The treatment of intestinal stoma is often a difficult experience for patients and results in numerous problems in the physical, psychological and social aspects. Therefore, post-operative care of the patient with the newly appointed stoma should be taken by therapeutic team consisting of doctors, nurses, physiotherapists, dieticians, psychologists and social workers. Appropriate nutritional education of patients aims to improve their quality of life and to prevent from unpleasant ailments formed after the operation. The specific type of stoma may decide about certain dietary recommendations. The presented work provides a practical dietary recommendations for patients with newly appointed stoma.

  8. SU-G-JeP3-09: Tumor Location Prediction Using Natural Respiratory Volume for Respiratory Gated Radiation Therapy (RGRT): System Verification Study

    Energy Technology Data Exchange (ETDEWEB)

    Kim, M; Jung, J; Yoon, D; Shin, H; Kim, S; Suh, T [The catholic university of Korea, Seoul (Korea, Republic of)

    2016-06-15

    Purpose: Respiratory gated radiation therapy (RGRT) gives accurate results when a patient’s breathing is stable and regular. Thus, the patient should be fully aware during respiratory pattern training before undergoing the RGRT treatment. In order to bypass the process of respiratory pattern training, we propose a target location prediction system for RGRT that uses only natural respiratory volume, and confirm its application. Methods: In order to verify the proposed target location prediction system, an in-house phantom set was used. This set involves a chest phantom including target, external markers, and motion generator. Natural respiratory volume signals were generated using the random function in MATLAB code. In the chest phantom, the target takes a linear motion based on the respiratory signal. After a four-dimensional computed tomography (4DCT) scan of the in-house phantom, the motion trajectory was derived as a linear equation. The accuracy of the linear equation was compared with that of the motion algorithm used by the operating motion generator. In addition, we attempted target location prediction using random respiratory volume values. Results: The correspondence rate of the linear equation derived from the 4DCT images with the motion algorithm of the motion generator was 99.41%. In addition, the average error rate of target location prediction was 1.23% for 26 cases. Conclusion: We confirmed the applicability of our proposed target location prediction system for RGRT using natural respiratory volume. If additional clinical studies can be conducted, a more accurate prediction system can be realized without requiring respiratory pattern training.

  9. Understanding radiation effects in SRAM-based field programmable gate arrays for implementing instrumentation and control systems of nuclear power plants

    Directory of Open Access Journals (Sweden)

    T.S. Nidhin

    2017-12-01

    Full Text Available Field programmable gate arrays (FPGAs are getting more attention in safety-related and safety-critical application development of nuclear power plant instrumentation and control systems. The high logic density and advancements in architectural features make static random access memory (SRAM-based FPGAs suitable for complex design implementations. Devices deployed in the nuclear environment face radiation particle strike that causes transient and permanent failures. The major reasons for failures are total ionization dose effects, displacement damage dose effects, and single event effects. Different from the case of space applications, soft errors are the major concern in terrestrial applications. In this article, a review of radiation effects on FPGAs is presented, especially soft errors in SRAM-based FPGAs. Single event upset (SEU shows a high probability of error in the dependable application development in FPGAs. This survey covers the main sources of radiation and its effects on FPGAs, with emphasis on SEUs as well as on the measurement of radiation upset sensitivity and irradiation experimental results at various facilities. This article also presents a comparison between the major SEU mitigation techniques in the configuration memory and user logics of SRAM-based FPGAs.

  10. A HOTLink/networked PC data acquisition and image reconstruction system for a high-resolution whole-body PET with respiratory or ECG-gated performance

    Science.gov (United States)

    Li, Hongdi; Xing, Tao; Liu, Yaqiang; Wang, Yu; Baghaei, H.; Uribe, J.; Ramirez, R.; Wong, Wai-Hoi

    2003-06-01

    An ultrahigh-resolution positron emission tomography (PET) camera in whole-body scanning or gated imaging study needs super computer-processing power for creating a huge sinogram as well as doing image reconstruction. A fast HOTLink serial bus attached to networked cluster personal computers (PC) has been developed for this special purpose. In general, the coincidence data from a PET camera is unidirectional; therefore, an additional daisy-chain bus using high-speed HOTLink (400 Mb/s, Cypress Semiconductor, inc.) transmitters and receivers is designed to carry the coincidence data to the entire networked (LAN) computers (PCs), the data from HOTLink are interfaced to a PC through a fast PCI I/O board (80 Mbyte/s). The overall architecture for the image acquisition and reconstruction computing system for a whole-body PET scanning is a pipeline design. One PC will acquire sinogram data for one bed position, and after completion of data acquisition that PC will begin to reconstruct the image. Meanwhile, another PC in the network will start data acquisition for the next bed position. The image results from the previous PC will be sent to a master computer for final tabulation and storage through the standard network, and then it will be free for processing a new bed position.

  11. The pollution of the 'iron gate' reservoir

    International Nuclear Information System (INIS)

    Babic-Mladenovic, M.; Varga, S; Popovic, L.; Damjanovic, M.

    2002-01-01

    The paper presents the characteristics of the Iron Gate I (the Djerdap) Water Power and Navigational System, one of the largest in Europe (completed in 1972 by joint efforts of Yugoslavia and Romania). In this paper the attention is devoted to review of the sediment monitoring program and impacts of reservoir sedimentation, as well as to the investigations of water and sediment quality. Special consideration is paid to the issue of sediment pollution research needs. Namely, the hot spot of the 'Iron Gate' sedimentation represents a scarcely known pollution of sediment deposits. The present pollution probably is considerable, since the 'Iron Gate' reservoir drains about 577000 km 2 , with over 80 million inhabitants, and developed municipal and industrial infrastructure. Therefore, in the thirty-year reservoir life various types of sediment-bound pollutants entered and deposited within it. Especially severe incidents happened during 1999 (as a result of NATO bombing campaign) and 2000 (two accidental pollutions in the Tisza river catchment). The study of the 'Iron Gate' reservoir pollution should be prepared in order to enlighten the present state of reservoir sedimentation and pollution. The main objectives of the study are to enhance the government and public awareness of the present environmental state of the 'Iron Gate' reservoir and to serve as a baseline for all future actions. (author)

  12. A Spaceborne Synthetic Aperture Radar Partial Fixed-Point Imaging System Using a Field- Programmable Gate Array-Application-Specific Integrated Circuit Hybrid Heterogeneous Parallel Acceleration Technique.

    Science.gov (United States)

    Yang, Chen; Li, Bingyi; Chen, Liang; Wei, Chunpeng; Xie, Yizhuang; Chen, He; Yu, Wenyue

    2017-06-24

    With the development of satellite load technology and very large scale integrated (VLSI) circuit technology, onboard real-time synthetic aperture radar (SAR) imaging systems have become a solution for allowing rapid response to disasters. A key goal of the onboard SAR imaging system design is to achieve high real-time processing performance with severe size, weight, and power consumption constraints. In this paper, we analyse the computational burden of the commonly used chirp scaling (CS) SAR imaging algorithm. To reduce the system hardware cost, we propose a partial fixed-point processing scheme. The fast Fourier transform (FFT), which is the most computation-sensitive operation in the CS algorithm, is processed with fixed-point, while other operations are processed with single precision floating-point. With the proposed fixed-point processing error propagation model, the fixed-point processing word length is determined. The fidelity and accuracy relative to conventional ground-based software processors is verified by evaluating both the point target imaging quality and the actual scene imaging quality. As a proof of concept, a field- programmable gate array-application-specific integrated circuit (FPGA-ASIC) hybrid heterogeneous parallel accelerating architecture is designed and realized. The customized fixed-point FFT is implemented using the 130 nm complementary metal oxide semiconductor (CMOS) technology as a co-processor of the Xilinx xc6vlx760t FPGA. A single processing board requires 12 s and consumes 21 W to focus a 50-km swath width, 5-m resolution stripmap SAR raw data with a granularity of 16,384 × 16,384.

  13. A Spaceborne Synthetic Aperture Radar Partial Fixed-Point Imaging System Using a Field- Programmable Gate Array−Application-Specific Integrated Circuit Hybrid Heterogeneous Parallel Acceleration Technique

    Directory of Open Access Journals (Sweden)

    Chen Yang

    2017-06-01

    Full Text Available With the development of satellite load technology and very large scale integrated (VLSI circuit technology, onboard real-time synthetic aperture radar (SAR imaging systems have become a solution for allowing rapid response to disasters. A key goal of the onboard SAR imaging system design is to achieve high real-time processing performance with severe size, weight, and power consumption constraints. In this paper, we analyse the computational burden of the commonly used chirp scaling (CS SAR imaging algorithm. To reduce the system hardware cost, we propose a partial fixed-point processing scheme. The fast Fourier transform (FFT, which is the most computation-sensitive operation in the CS algorithm, is processed with fixed-point, while other operations are processed with single precision floating-point. With the proposed fixed-point processing error propagation model, the fixed-point processing word length is determined. The fidelity and accuracy relative to conventional ground-based software processors is verified by evaluating both the point target imaging quality and the actual scene imaging quality. As a proof of concept, a field- programmable gate array−application-specific integrated circuit (FPGA-ASIC hybrid heterogeneous parallel accelerating architecture is designed and realized. The customized fixed-point FFT is implemented using the 130 nm complementary metal oxide semiconductor (CMOS technology as a co-processor of the Xilinx xc6vlx760t FPGA. A single processing board requires 12 s and consumes 21 W to focus a 50-km swath width, 5-m resolution stripmap SAR raw data with a granularity of 16,384 × 16,384.

  14. An appointment-based model to systematically assess and administer vaccinations.

    Science.gov (United States)

    Luder, Heidi R; Kunze, Natalie; Heaton, Pamela C; Frede, Stacey M

    2018-03-27

    To incorporate the assessment of vaccination status and administration of vaccines in an appointment-based model (ABM) and measure the impact on vaccinations administered and patient and pharmacist satisfaction with the appointment-based model. An ABM was implemented to systematically assess vaccination status and administer vaccines. Patients made an appointment to pick up synchronized prescriptions, and pharmacists assessed vaccination histories and administered vaccinations during the appointment. In addition, pharmacists could access the statewide immunization information system to objectively determine vaccination histories and document administered vaccines. This project was conducted at 24 Kroger Pharmacies in the Cincinnati-Dayton Area. Any patient filling more than 1 maintenance medication was eligible for the ABM program. Pharmacists were encouraged to target patients at high risk for medication problems and vaccine-preventable diseases, including patients 60 years of age or older with more than 5 medications and high-risk disease states such as diabetes, asthma, and chronic obstructive pulmonary disease. Pharmacies were randomized, and an a priori analysis was conducted to ensure that the 24 intervention and 78 control stores were similar at baseline. Postimplementation data on the mean number of vaccines per store were compared between the intervention stores and the control stores from September 2014 through December 2015. Patient and pharmacist satisfaction with the ABM was assessed via surveys. The pharmacist vaccine assessment as part of the ABM program showed higher overall mean vaccinations per store compared with the control group during the project period (1810.71 ± 500.88 vs. 1455.09 ± 754.43; P = 0.01). Patients and pharmacists felt that the ABM program facilitated vaccine discussions. The ABM program with a focus on vaccinations allowed pharmacists to systematically assess patient vaccination histories and administer vaccines in the

  15. A missed primary care appointment correlates with a subsequent emergency department visit among children with asthma.

    Science.gov (United States)

    McGovern, Colleen Marie; Redmond, Margaret; Arcoleo, Kimberly; Stukus, David R

    2017-11-01

    Since the Affordable Care Act's implementation, emergency department (ED) visits have increased. Poor asthma control increases the risk of acute exacerbations and preventable ED visits. The Centers for Medicare and Medicaid Services support the reduction of preventable ED visits to reduce healthcare spending. Implementation of interventions to avoid preventable ED visits has become a priority for many healthcare systems yet little data exist examining children's missed asthma management primary care (PC) appointments and subsequent ED visits. Longitudinal, retrospective review at a children's hospital was conducted for children with diagnosed asthma (ICD-9 493.xx), ages 2-18 years, scheduled for a PC visit between January 1, 2010, and June 30, 2012 (N = 3895). Records were cross-referenced with all asthma-related ED visits from January 1, 2010 to December 31, 2012. Logistic regression with maximum likelihood estimation was conducted. None of the children who completed a PC appointment experienced an ED visit in the subsequent 6 months whereas 2.7% of those with missed PC appointments had an ED visit (χ 2 = 64.28, p asthma as one mechanism for preventing ED visits was demonstrated. Interventions targeting missed visits could decrease asthma-related morbidity, preventable ED visits, and healthcare costs.

  16. High permittivity gate dielectric materials

    CERN Document Server

    2013-01-01

    "The book comprehensively covers all the current and the emerging areas of the physics and the technology of high permittivity gate dielectric materials, including, topics such as MOSFET basics and characteristics, hafnium-based gate dielectric materials, Hf-based gate dielectric processing, metal gate electrodes, flat-band and threshold voltage tuning, channel mobility, high-k gate stack degradation and reliability, lanthanide-based high-k gate stack materials, ternary hafnia and lanthania based high-k gate stack films, crystalline high-k oxides, high mobility substrates, and parameter extraction. Each chapter begins with the basics necessary for understanding the topic, followed by a comprehensive review of the literature, and ultimately graduating to the current status of the technology and our scientific understanding and the future prospects."

  17. Modelling of coulometric sensor-actuator systems based on ISFETs with a porous actuator covering the gate

    NARCIS (Netherlands)

    Luo, J.; Luo, J.; Olthuis, Wouter; Bergveld, Piet; Bos, M.; van der Linden, W.E.

    1993-01-01

    The ion-selective field effect transistor (ISFET)-based coulometric sensor¿actuator systems have found applications in acid¿base titration and in the construction of a low-drift carbon dioxide and a pH-static enzyme sensor. In this paper a brief review is given of the previously developed

  18. 76 FR 54071 - Noncompetitive Appointment of Certain Military Spouses

    Science.gov (United States)

    2011-08-31

    ... Integrated Process Team. The Integrated Process Team (IPT) found that spouses of service members who were... inconsistency between this group and other individuals eligible for noncompetitive entry into Federal service... advantage as military spouses. Executive Order 13473 authorizes noncompetitive appointment only for certain...

  19. 29 CFR 4221.4 - Appointment of the arbitrator.

    Science.gov (United States)

    2010-07-01

    ... appointment shall include a copy of the notice or agreement initiating arbitration, a statement that the... likely to affect his or her impartiality, including any bias or any financial or personal interest in the... accordance with paragraph (d) of this section. (c) Challenge and withdrawal. After the arbitrator has been...

  20. 5 CFR 930.204 - Appointments and conditions of employment.

    Science.gov (United States)

    2010-01-01

    ... promotion of administrative law judges. (2) To reclassify an administrative law judge position at a higher... will direct the promotion of the administrative law judge occupying the position prior to the... 5 Administrative Personnel 2 2010-01-01 2010-01-01 false Appointments and conditions of employment...

  1. 77 FR 42901 - Noncompetitive Appointment of Certain Former Overseas Employees

    Science.gov (United States)

    2012-07-20

    ... to Same-Sex Domestic Partners of Federal Employees,'' which provides standard definitions for... are not same-sex partners. OPM disagrees, noting that the definition of ``family member'' has simply..., 591, et al. Same-Sex Domestic Partners: Noncompetitive Appointment of Certain Former Overseas...

  2. Why Patients Miss Follow-Up Appointments: A Prospective Control ...

    African Journals Online (AJOL)

    Reasons include: transport (19 responses), ill-health (6) and financial constraints (5). State transport was unavailable to almost twothirds of the responders who cited transport as a problem. Conclusions: The 17% missed appointment rate is largely due to transport constraints. The commonest time for patients to miss ...

  3. Legislation on school governors' power to appoint educators: friend ...

    African Journals Online (AJOL)

    Erna Kinsey

    18.3) refers to the powers that management councils at school level should have to appoint teaching staff for extra-mural activities. This also seems to accept that the state will employ all educators at schools. The same paragraph introduces the notion of the subvention of educators' salaries by management councils which ...

  4. IZINDABA: A timely appointment - SAMA\\'s new CEO | Bateman ...

    African Journals Online (AJOL)

    IZINDABA: A timely appointment - SAMA\\'s new CEO. Chris Bateman. Abstract. No abstract. South African Medical Journal Vol. 95 (8) 2005: 554-556. Full Text: EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT · AJOL African Journals Online. HOW TO USE AJOL.

  5. Approaches taken by South African advertisers to select and appoint ...

    African Journals Online (AJOL)

    Pitch and industry guidelines play an important role in awarding advertising agency contracts, but agencies must take into account that not all advertisers will adhere to these guidelines. The exploratory research study on which this article reports provides insight into the appointment process and selection criteria applied ...

  6. Improving Patient Schedules by Multi-agent Pareto Appointment Exchanging

    NARCIS (Netherlands)

    I.B. Vermeulen (Ivan); S.M. Bohte (Sander); D.J.A. Somefun (Koye); J.A. La Poutré (Han)

    2006-01-01

    textabstractWe present a dynamic and distributed approach to the hospital patient scheduling problem: the multi-agent Pareto-improvement appointment exchanging algorithm, MPAEX. It respects the decentralization of scheduling authorities and is capable of continuously adjusting the different patient

  7. Static and dynamic appointment scheduling to improve patient access time

    NARCIS (Netherlands)

    van de Vrugt, Maartje; Laan, Corine Maartje; Olsman, Jan; Boucherie, Richardus J.

    2017-01-01

    Appointment schedules for outpatient clinics have great influence on efficiency and timely access to health care services. The number of new patients per week fluctuates, and capacity at the clinic varies because physicians have other obligations. However, most outpatient clinics use static

  8. 75 FR 32245 - Delegation of Authority to Appoint Commissioned

    Science.gov (United States)

    2010-06-08

    ... From the Federal Register Online via the Government Publishing Office #0; #0; #0; Presidential Documents #0; #0; #0;#0;Federal Register / Vol. 75 , No. 109 / Tuesday, June 8, 2010 / Presidential Documents#0;#0; #0; #0;Title 3-- #0;The President ] Memorandum of June 1, 2010 Delegation of Authority to Appoint Commissioned Officers of the Ready Reserve Corps of the Public...

  9. 'Single' v. 'panel' appointed forensic mental observations: Is the ...

    African Journals Online (AJOL)

    Objective. To compare the outcome and psychiatric morbidity of the forensic mental observation referrals, in the two legally created groups of detainees awaiting trial – the 'singles', representing the minor violent and non-violent offenders evaluated by a single-state appointed psychiatrist, v. the 'panels', representing the ...

  10. Legislative approval of executive appointments by the national ...

    African Journals Online (AJOL)

    ... in a patriotic manner in order to engender good governance? The paper concludes that the power should be exercised in a way that peace, order and good governance shall be promoted both at the Federal and State levels. Keywords: Executive appointments, Legislative approval, National Assembly, Constitutional duty ...

  11. Diminished auditory sensory gating during active auditory verbal hallucinations.

    Science.gov (United States)

    Thoma, Robert J; Meier, Andrew; Houck, Jon; Clark, Vincent P; Lewine, Jeffrey D; Turner, Jessica; Calhoun, Vince; Stephen, Julia

    2017-10-01

    Auditory sensory gating, assessed in a paired-click paradigm, indicates the extent to which incoming stimuli are filtered, or "gated", in auditory cortex. Gating is typically computed as the ratio of the peak amplitude of the event related potential (ERP) to a second click (S2) divided by the peak amplitude of the ERP to a first click (S1). Higher gating ratios are purportedly indicative of incomplete suppression of S2 and considered to represent sensory processing dysfunction. In schizophrenia, hallucination severity is positively correlated with gating ratios, and it was hypothesized that a failure of sensory control processes early in auditory sensation (gating) may represent a larger system failure within the auditory data stream; resulting in auditory verbal hallucinations (AVH). EEG data were collected while patients (N=12) with treatment-resistant AVH pressed a button to indicate the beginning (AVH-on) and end (AVH-off) of each AVH during a paired click protocol. For each participant, separate gating ratios were computed for the P50, N100, and P200 components for each of the AVH-off and AVH-on states. AVH trait severity was assessed using the Psychotic Symptoms Rating Scales AVH Total score (PSYRATS). The results of a mixed model ANOVA revealed an overall effect for AVH state, such that gating ratios were significantly higher during the AVH-on state than during AVH-off for all three components. PSYRATS score was significantly and negatively correlated with N100 gating ratio only in the AVH-off state. These findings link onset of AVH with a failure of an empirically-defined auditory inhibition system, auditory sensory gating, and pave the way for a sensory gating model of AVH. Copyright © 2017 Elsevier B.V. All rights reserved.

  12. Evaluation of accuracy about 2D vs 3D real-time position management system based on couch rotation when non-coplanar respiratory gated radiation therapy

    Energy Technology Data Exchange (ETDEWEB)

    Kwon, Kyung Tae; Kim, Jung Soo [Dongnam Health University, Suwon (Korea, Republic of); Sim, Hyun Sun [College of Health Sciences, Korea University, Seoul (Korea, Republic of); Min, Jung Whan [Shingu University College, Sungnam (Korea, Republic of); Son, Soon Yong [Wonkwang Health Science University, Iksan (Korea, Republic of); Han, Dong Kyoon [College of Health Sciences, EulJi University, Daejeon (Korea, Republic of)

    2016-12-15

    Because of non-coplanar therapy with couch rotation in respiratory gated radiation therapy, the recognition of marker movement due to the change in the distance between the infrared camera and the marker due to the rotation of the couch is called RPM (Real-time The purpose of this paper is to evaluate the accuracy of motion reflections (baseline changes) of 2D gating configuration (two dot marker block) and 3D gating configuration (six dot marker block). The motion was measured by varying the couch angle in the clockwise and counterclockwise directions by 10° in the 2D gating configuration. In the 3D gating configuration, the couch angle was changed by 10° in the clockwise direction and compared with the baseline at the reference 0°. The reference amplitude was 1.173 to 1.165, the couch angle at 20° was 1.132, and the couch angle at 1.0° was 1.083. At 350° counterclockwise, the reference amplitude was 1.168 to 1.157, the couch angle at 340° was 1.124, and the couch angle at 330° was 1.079. In this study, the phantom is used to quantitatively evaluate the value of the amplitude according to couch change.

  13. Single-atom gating and magnetic interactions in quantum corrals

    Energy Technology Data Exchange (ETDEWEB)

    Ngo, Anh T.; Kim, Eugene H.; Ulloa, Sergio E.

    2017-04-01

    Single-atom gating, achieved by manipulation of adatoms on a surface, has been shown in experiments to allow precise control over superposition of electronic states in quantum corrals. Using a Green's function approach, we demonstrate theoretically that such atom gating can also be used to control the coupling between magnetic degrees of freedom in these systems. Atomic gating enables control not only on the direct interaction between magnetic adatoms, but also over superpositions of many-body states which can then control long distance interactions. We illustrate this effect by considering the competition between direct exchange between magnetic impurities and the Kondo screening mediated by the host electrons, and how this is affected by gating. These results suggest that both magnetic and nonmagnetic single-atom gating may be used to investigate magnetic impurity systems with tailored interactions, and may allow the control of entanglement of different spin states.

  14. Noise Gating Solar Images

    Science.gov (United States)

    DeForest, Craig; Seaton, Daniel B.; Darnell, John A.

    2017-08-01

    I present and demonstrate a new, general purpose post-processing technique, "3D noise gating", that can reduce image noise by an order of magnitude or more without effective loss of spatial or temporal resolution in typical solar applications.Nearly all scientific images are, ultimately, limited by noise. Noise can be direct Poisson "shot noise" from photon counting effects, or introduced by other means such as detector read noise. Noise is typically represented as a random variable (perhaps with location- or image-dependent characteristics) that is sampled once per pixel or once per resolution element of an image sequence. Noise limits many aspects of image analysis, including photometry, spatiotemporal resolution, feature identification, morphology extraction, and background modeling and separation.Identifying and separating noise from image signal is difficult. The common practice of blurring in space and/or time works because most image "signal" is concentrated in the low Fourier components of an image, while noise is evenly distributed. Blurring in space and/or time attenuates the high spatial and temporal frequencies, reducing noise at the expense of also attenuating image detail. Noise-gating exploits the same property -- "coherence" -- that we use to identify features in images, to separate image features from noise.Processing image sequences through 3-D noise gating results in spectacular (more than 10x) improvements in signal-to-noise ratio, while not blurring bright, resolved features in either space or time. This improves most types of image analysis, including feature identification, time sequence extraction, absolute and relative photometry (including differential emission measure analysis), feature tracking, computer vision, correlation tracking, background modeling, cross-scale analysis, visual display/presentation, and image compression.I will introduce noise gating, describe the method, and show examples from several instruments (including SDO

  15. An electronically controlled automatic security access gate

    Directory of Open Access Journals (Sweden)

    Jonathan A. ENOKELA

    2014-11-01

    Full Text Available The security challenges being encountered in many places require electronic means of controlling access to communities, recreational centres, offices, and homes. The electronically controlled automated security access gate being proposed in this work helps to prevent an unwanted access to controlled environments. This is achieved mainly through the use of a Radio Frequency (RF transmitter-receiver pair. In the design a microcontroller is programmed to decode a given sequence of keys that is entered on a keypad and commands a transmitter module to send out this code as signal at a given radio frequency. Upon reception of this RF signal by the receiver module, another microcontroller activates a driver circuitry to operate the gate automatically. The codes for the microcontrollers were written in C language and were debugged and compiled using the KEIL Micro vision 4 integrated development environment. The resultant Hex files were programmed into the memories of the microcontrollers with the aid of a universal programmer. Software simulation was carried out using the Proteus Virtual System Modeling (VSM version 7.7. A scaled-down prototype of the system was built and tested. The electronically controlled automated security access gate can be useful in providing security for homes, organizations, and automobile terminals. The four-character password required to operate the gate gives the system an increased level of security. Due to its standalone nature of operation the system is cheaper to maintain in comparison with a manually operated type.

  16. Field Programmable Gate Array (FPGA) for Bio-Inspired Visuo-Motor Control Systems Applied to Micro-Air Vehicles

    OpenAIRE

    Aubepart, Fabrice; Serres, Julien; Dilly, Antoine; Ruffier, Franck; Franceschini, Nicolas

    2009-01-01

    We have developed a digital integration of an autopilot called LORA III (Serres et al. 2008a) onto a Virtex-4 FPGA. The autopilot consists of two interdependent visuo-motor control loops that are meant to control the visual guidance of a miniature hovercraft in a corridor without any measurements of speed and distance from the walls. A top-down methodology was used to design and simulate the overall visuo-motor control system. The latter was studied using both a high-level graphical environme...

  17. Functional importance of T-type voltage-gated calcium channels in the cardiovascular and renal system

    DEFF Research Database (Denmark)

    Hansen, Pernille B L

    2015-01-01

    Over the years, it has been discussed whether T-type calcium channels Cav3 play a role in the cardiovascular and renal system. T-type channels have been reported to play an important role in renal hemodynamics, contractility of resistance vessels, and pacemaker activity in the heart. However......, the lack of highly specific blockers cast doubt on the conclusions. As new T-type channel antagonists are being designed, the roles of T-type channels in cardiovascular and renal pathology need to be elucidated before T-type blockers can be clinically useful. Two types of T-type channels, Cav3.1 and Cav3...

  18. Design verification enhancement of field programmable gate array-based safety-critical I&C system of nuclear power plant

    Energy Technology Data Exchange (ETDEWEB)

    Ahmed, Ibrahim [Department of Nuclear Engineering, Kyung Hee University, 1732 Deogyeong-daero, Giheung-gu, Yongin-si, Gyeonggi-do 17104 (Korea, Republic of); Jung, Jaecheon, E-mail: jcjung@kings.ac.kr [Department of Nuclear Power Plant Engineering, KEPCO International Nuclear Graduate School, 658-91 Haemaji-ro, Seosang-myeon, Ulju-gun, Ulsan 45014 (Korea, Republic of); Heo, Gyunyoung [Department of Nuclear Engineering, Kyung Hee University, 1732 Deogyeong-daero, Giheung-gu, Yongin-si, Gyeonggi-do 17104 (Korea, Republic of)

    2017-06-15

    Highlights: • An enhanced, systematic and integrated design verification approach is proposed for V&V of FPGA-based I&C system of NPP. • RPS bistable fixed setpoint trip algorithm is designed, analyzed, verified and discussed using the proposed approaches. • The application of integrated verification approach simultaneously verified the entire design modules. • The applicability of the proposed V&V facilitated the design verification processes. - Abstract: Safety-critical instrumentation and control (I&C) system in nuclear power plant (NPP) implemented on programmable logic controllers (PLCs) plays a vital role in safe operation of the plant. The challenges such as fast obsolescence, the vulnerability to cyber-attack, and other related issues of software systems have currently led to the consideration of field programmable gate arrays (FPGAs) as an alternative to PLCs because of their advantages and hardware related benefits. However, safety analysis for FPGA-based I&C systems, and verification and validation (V&V) assessments still remain important issues to be resolved, which are now become a global research point of interests. In this work, we proposed a systematic design and verification strategies from start to ready-to-use in form of model-based approaches for FPGA-based reactor protection system (RPS) that can lead to the enhancement of the design verification and validation processes. The proposed methodology stages are requirement analysis, enhanced functional flow block diagram (EFFBD) models, finite state machine with data path (FSMD) models, hardware description language (HDL) code development, and design verifications. The design verification stage includes unit test – Very high speed integrated circuit Hardware Description Language (VHDL) test and modified condition decision coverage (MC/DC) test, module test – MATLAB/Simulink Co-simulation test, and integration test – FPGA hardware test beds. To prove the adequacy of the proposed

  19. Design verification enhancement of field programmable gate array-based safety-critical I&C system of nuclear power plant

    International Nuclear Information System (INIS)

    Ahmed, Ibrahim; Jung, Jaecheon; Heo, Gyunyoung

    2017-01-01

    Highlights: • An enhanced, systematic and integrated design verification approach is proposed for V&V of FPGA-based I&C system of NPP. • RPS bistable fixed setpoint trip algorithm is designed, analyzed, verified and discussed using the proposed approaches. • The application of integrated verification approach simultaneously verified the entire design modules. • The applicability of the proposed V&V facilitated the design verification processes. - Abstract: Safety-critical instrumentation and control (I&C) system in nuclear power plant (NPP) implemented on programmable logic controllers (PLCs) plays a vital role in safe operation of the plant. The challenges such as fast obsolescence, the vulnerability to cyber-attack, and other related issues of software systems have currently led to the consideration of field programmable gate arrays (FPGAs) as an alternative to PLCs because of their advantages and hardware related benefits. However, safety analysis for FPGA-based I&C systems, and verification and validation (V&V) assessments still remain important issues to be resolved, which are now become a global research point of interests. In this work, we proposed a systematic design and verification strategies from start to ready-to-use in form of model-based approaches for FPGA-based reactor protection system (RPS) that can lead to the enhancement of the design verification and validation processes. The proposed methodology stages are requirement analysis, enhanced functional flow block diagram (EFFBD) models, finite state machine with data path (FSMD) models, hardware description language (HDL) code development, and design verifications. The design verification stage includes unit test – Very high speed integrated circuit Hardware Description Language (VHDL) test and modified condition decision coverage (MC/DC) test, module test – MATLAB/Simulink Co-simulation test, and integration test – FPGA hardware test beds. To prove the adequacy of the proposed

  20. A new universal gate for low power SoC applications

    Indian Academy of Sciences (India)

    This paper formulates a new design technique for an area and energy efficient Universal NAND gate. The proposed robust three transistors (3T) based NAND gate is just as effective for dynamic power control in CMOS VLSI circuits for System on Chip (SoC) applications. The 3T NAND gate is intuitively momentous and lead ...

  1. 100-nm gate lithography for double-gate transistors

    Science.gov (United States)

    Krasnoperova, Azalia A.; Zhang, Ying; Babich, Inna V.; Treichler, John; Yoon, Jung H.; Guarini, Kathryn; Solomon, Paul M.

    2001-09-01

    The double gate field effect transistor (FET) is an exploratory device that promises certain performance advantages compared to traditional CMOS FETs. It can be scaled down further than the traditional devices because of the greater electrostatic control by the gates on the channel (about twice as short a channel length for the same gate oxide thickness), has steeper sub-threshold slope and about double the current for the same width. This paper presents lithographic results for double gate FET's developed at IBM's T. J. Watson Research Center. The device is built on bonded wafers with top and bottom gates self-aligned to each other. The channel is sandwiched between the top and bottom polysilicon gates and the gate length is defined using DUV lithography. An alternating phase shift mask was used to pattern gates with critical dimensions of 75 nm, 100 nm and 125 nm in photoresist. 50 nm gates in photoresist have also been patterned by 20% over-exposure of nominal 100 nm lines. No trim mask was needed because of a specific way the device was laid out. UV110 photoresist from Shipley on AR-3 antireflective layer were used. Process windows, developed and etched patterns are presented.

  2. Gate-first integration of tunable work function metal gates of different thicknesses into high-k metal gates CMOS FinFETs for multi- VTh engineering

    KAUST Repository

    Hussain, Muhammad Mustafa

    2010-03-01

    Gate-first integration of tunable work function metal gates of different thicknesses (320 nm) into high-k/metal gates CMOS FinFETs was demonstrated to achieve multiple threshold voltages (VTh) for 32-nm technology and beyond logic, memory, input/output, and system-on-a-chip applications. The fabricated devices showed excellent short-channel effect immunity (drain-induced barrier lowering ∼ 40 mV/V), nearly symmetric VTh, low T inv(∼ 1.4 nm), and high Ion(∼780μAμm) for N/PMOS without any intentional strain enhancement. © 2006 IEEE.

  3. 75 FR 74748 - Senior Executive Service; Appointment of Members to the Performance Review Board

    Science.gov (United States)

    2010-12-01

    ... Regulatory and Programmatic Policy--appointment expires on 09/30/12 BLS John M. Galvin, Associate... Assistant Secretary for Policy-- appointment expires on 09/30/12 OASAM Milton A. Stewart, Director, Business...

  4. Expert Oracle GoldenGate

    CERN Document Server

    Prusinski, Ben; Chung, Richard

    2011-01-01

    Expert Oracle GoldenGate is a hands-on guide to creating and managing complex data replication environments using the latest in database replication technology from Oracle. GoldenGate is the future in replication technology from Oracle, and aims to be best-of-breed. GoldenGate supports homogeneous replication between Oracle databases. It supports heterogeneous replication involving other brands such as Microsoft SQL Server and IBM DB2 Universal Server. GoldenGate is high-speed, bidirectional, highly-parallelized, and makes only a light impact on the performance of databases involved in replica

  5. Dimensões da governança judicial e sua aplicação ao sistema judicial brasileiro Judicial governance dimensions and their appointment to the Brazilian judicial system

    Directory of Open Access Journals (Sweden)

    Luiz Akutsu

    2012-06-01

    Full Text Available A administração da Justiça brasileira enfrenta dificuldades crônicas de acessibilidade da população de menor renda à Justiça, de morosidade e de baixa eficácia das deliberações judiciais. O presente estudo busca contribuir para o exame de soluções para tais dificuldades, tendo como objetivos identificar dimensões relacionadas ao conceito de governança judicial estudadas em pesquisas empíricas recentes e discutir como tais dimensões podem influenciar o desempenho do sistema judicial brasileiro. As seguintes dimensões foram identificadas: independência judicial; accountability; acessibilidade à Justiça; estrutura do Poder Judiciário; recursos estratégicos do Poder Judiciário; e desempenho do sistema judicial. Ante a escassez de estudos empíricos sobre gestão do judiciário em geral e do Brasil em particular, foram formuladas propostas de pesquisas para avaliar, entre outros aspectos: (a a influência do desenvolvimento dos recursos estratégicos no desempenho do Poder Judiciário; e (b o impacto, na diminuição da corrupção do sistema judicial brasileiro, do aumento da independência judicial e da garantia de que os juízes sejam accountables perante a sociedade.The Brazilian justice management faces chronic difficulties of accessibility of lower income population to justice, the slowness and low effectiveness of the judicial decisions. In order to contribute to the analysis of solutions to these difficulties, the objectives of this paper are to identify dimensions related to the concept of judicial governance studied in recent empirical researches, and discuss how these dimensions can push the performance of the Brazilian judicial system. The following dimensions were identified: Judicial Independence, Accountability, Accessibility to Justice; Structure of the Judiciary; Strategic Resources of the Judiciary, and Judiciary's Performance. Faced with the scarcity of empirical studies on management of the judiciary

  6. Scheduling Patients’ Appointments: Allocation of Healthcare Service Using Simulation Optimization

    Directory of Open Access Journals (Sweden)

    Ping-Shun Chen

    2015-01-01

    Full Text Available In the service industry, scheduling medical procedures causes difficulties for both patients and management. Factors such as fluctuations in customer demand and service time affect the appointment scheduling systems’ performance in terms of, for example, patients’ waiting time, idle time of resources, and total cost/profits. This research implements four appointment scheduling policies, i.e., constant arrival, mixed patient arrival, three-section pattern arrival, and irregular arrival, in an ultrasound department of a hospital in Taiwan. By simulating the four implemented policies’ optimization procedures, optimal or near-optimal solutions can be obtained for patients per arrival, patients’ inter-arrival time, and the number of the time slots for arrived patients. Furthermore, three objective functions are tested, and the results are discussed. The managerial implications and discussions are summarized to demonstrate how outcomes can be useful for hospital managers seeking to allocate their healthcare service capacities.

  7. A Heart Failure Management Program Using Shared Medical Appointments.

    Science.gov (United States)

    Carroll, Allison J; Howrey, Hillary L; Payvar, Susan; Deshida-Such, Kristen; Kansal, Mayank; Brar, Charanjit K

    2017-04-01

    Disease management programs for heart failure (HF) effectively reduce HF-related hospitalization rates and mortality. Shared medical appointments (SMAs) offer a cost-effective delivery method for HF disease management programs. However, few studies have evaluated this cost-effective delivery method of HF disease management among Veterans with acute HF. We hypothesized that Veterans who attended a multidisciplinary HF-SMA clinic promoting HF self-management, compared those who only received individual treatment through the HF specialty clinic, would have better 12-month hospitalization outcomes. We completed a retrospective review of the VA electronic health record for HF-SMA clinic appointments (1/1/2012 to 12/31/2013). The multidisciplinary HF-SMA program comprised 4 weekly sessions covering topics including HF disease, HF medications, diet adherence, physical activity, psychological well-being, and stress management. Patients who attended the HF-SMA clinic ( n =54) were compared to patients who were scheduled for an HF-SMA appointment but never attended and were followed only in the HF clinic ( n =37). Outcomes were 12-month HF-related and all-cause hospitalization rates, days in the hospital, and time to first hospitalization. Of 141 patients scheduled for an HF-SMA clinic appointment, 54 met criteria for the HF-SMA clinic group and 37 were included in the HF clinic group. The groups did not significantly differ on any sociodemographic variables. Furthermore, no significant differences were observed between the HF-SMA group and the HF clinic group on demographics or hospitalization outcomes, p >.05 for all comparisons. Our results did not support our hypothesis that offering multidisciplinary, HF-SMAs promoting HF self-management skills, above and beyond the individual disease management care provided in an HF specialty clinic, would improve hospitalization outcomes among Veterans with acute HF. Limitations of the present study and recommendations for HF self

  8. Bonded indirect restorations for posterior teeth: the luting appointment

    OpenAIRE

    Rocca, Giovanni Tommaso; Krejci, Ivo

    2007-01-01

    Classic bonded indirect restorations are laboratory fabricated and require 2 appointments: one for provisionalization and one for luting. This article describes the adhesive luting procedure, from try-in of the workpiece to finishing and polishing after the adhesive cementation, and it represents the second part of an updated technique for bonded inlays and onlays. The clinical sequence is described step by step with 2 cases. Particular attention is given to the adhesive treatment of the rest...

  9. Council appoints CERN’s next Director General

    CERN Multimedia

    Maximilien Brice

    2007-01-01

    On 14 December 2007, CERN Council appointed Professor Rolf-Dieter Heuer to succeed Dr Robert Aymar as CERN Director General. Professor Heuer will serve a five-year term, taking office on 1 January 2009. From Left to right: Dr Robert Aymar, current CERN Director General, Professor Torsten Åkesson, President of CERN Council, and Professor Rolf-Dieter Heuer, CERN's next Director General.

  10. 25 CFR 11.704 - Appointment and duties of executor or administrator.

    Science.gov (United States)

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false Appointment and duties of executor or administrator. 11... OF INDIAN OFFENSES AND LAW AND ORDER CODE Probate Proceedings § 11.704 Appointment and duties of executor or administrator. (a) Upon ordering the estate to be probated, the court shall appoint an...

  11. 45 CFR 211.5 - Action under State law; appointment of guardian.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 2 2010-10-01 2010-10-01 false Action under State law; appointment of guardian... Action under State law; appointment of guardian. Whenever an eligible person is incapable of giving his... appointment of a legal guardian, to ensure the proper planning for and provision of such care and treatment. ...

  12. Integration of biomolecular logic gates with field-effect transducers

    International Nuclear Information System (INIS)

    Poghossian, A.; Malzahn, K.; Abouzar, M.H.; Mehndiratta, P.; Katz, E.; Schoening, M.J.

    2011-01-01

    Highlights: → Enzyme-based AND/OR logic gates are integrated with a capacitive field-effect sensor. → The AND/OR logic gates compose of multi-enzyme system immobilised on sensor surface. → Logic gates were activated by different combinations of chemical inputs (analytes). → The logic output (pH change) produced by the enzymes was read out by the sensor. - Abstract: The integration of biomolecular logic gates with field-effect devices - the basic element of conventional electronic logic gates and computing - is one of the most attractive and promising approaches for the transformation of biomolecular logic principles into macroscopically useable electrical output signals. In this work, capacitive field-effect EIS (electrolyte-insulator-semiconductor) sensors based on a p-Si-SiO 2 -Ta 2 O 5 structure modified with a multi-enzyme membrane have been used for electronic transduction of biochemical signals processed by enzyme-based OR and AND logic gates. The realised OR logic gate composes of two enzymes (glucose oxidase and esterase) and was activated by ethyl butyrate or/and glucose. The AND logic gate composes of three enzymes (invertase, mutarotase and glucose oxidase) and was activated by two chemical input signals: sucrose and dissolved oxygen. The developed integrated enzyme logic gates produce local pH changes at the EIS sensor surface as a result of biochemical reactions activated by different combinations of chemical input signals, while the pH value of the bulk solution remains unchanged. The pH-induced charge changes at the gate-insulator (Ta 2 O 5 ) surface of the EIS transducer result in an electronic signal corresponding to the logic output produced by the immobilised enzymes. The logic output signals have been read out by means of a constant-capacitance method.

  13. Integration of biomolecular logic gates with field-effect transducers

    Energy Technology Data Exchange (ETDEWEB)

    Poghossian, A., E-mail: a.poghossian@fz-juelich.de [Institute of Nano- and Biotechnologies, Aachen University of Applied Sciences, Campus Juelich, Heinrich-Mussmann-Str. 1, D-52428 Juelich (Germany); Institute of Bio- and Nanosystems, Research Centre Juelich GmbH, D-52425 Juelich (Germany); Malzahn, K. [Institute of Nano- and Biotechnologies, Aachen University of Applied Sciences, Campus Juelich, Heinrich-Mussmann-Str. 1, D-52428 Juelich (Germany); Abouzar, M.H. [Institute of Nano- and Biotechnologies, Aachen University of Applied Sciences, Campus Juelich, Heinrich-Mussmann-Str. 1, D-52428 Juelich (Germany); Institute of Bio- and Nanosystems, Research Centre Juelich GmbH, D-52425 Juelich (Germany); Mehndiratta, P. [Institute of Nano- and Biotechnologies, Aachen University of Applied Sciences, Campus Juelich, Heinrich-Mussmann-Str. 1, D-52428 Juelich (Germany); Katz, E. [Department of Chemistry and Biomolecular Science, NanoBio Laboratory (NABLAB), Clarkson University, Potsdam, NY 13699-5810 (United States); Schoening, M.J. [Institute of Nano- and Biotechnologies, Aachen University of Applied Sciences, Campus Juelich, Heinrich-Mussmann-Str. 1, D-52428 Juelich (Germany); Institute of Bio- and Nanosystems, Research Centre Juelich GmbH, D-52425 Juelich (Germany)

    2011-11-01

    Highlights: > Enzyme-based AND/OR logic gates are integrated with a capacitive field-effect sensor. > The AND/OR logic gates compose of multi-enzyme system immobilised on sensor surface. > Logic gates were activated by different combinations of chemical inputs (analytes). > The logic output (pH change) produced by the enzymes was read out by the sensor. - Abstract: The integration of biomolecular logic gates with field-effect devices - the basic element of conventional electronic logic gates and computing - is one of the most attractive and promising approaches for the transformation of biomolecular logic principles into macroscopically useable electrical output signals. In this work, capacitive field-effect EIS (electrolyte-insulator-semiconductor) sensors based on a p-Si-SiO{sub 2}-Ta{sub 2}O{sub 5} structure modified with a multi-enzyme membrane have been used for electronic transduction of biochemical signals processed by enzyme-based OR and AND logic gates. The realised OR logic gate composes of two enzymes (glucose oxidase and esterase) and was activated by ethyl butyrate or/and glucose. The AND logic gate composes of three enzymes (invertase, mutarotase and glucose oxidase) and was activated by two chemical input signals: sucrose and dissolved oxygen. The developed integrated enzyme logic gates produce local pH changes at the EIS sensor surface as a result of biochemical reactions activated by different combinations of chemical input signals, while the pH value of the bulk solution remains unchanged. The pH-induced charge changes at the gate-insulator (Ta{sub 2}O{sub 5}) surface of the EIS transducer result in an electronic signal corresponding to the logic output produced by the immobilised enzymes. The logic output signals have been read out by means of a constant-capacitance method.

  14. Works close to gate B

    CERN Document Server

    GS Department

    2011-01-01

    In connection to the TRAM project, drainage works will be carried out close to gate B until the end of next week. In order to avoid access problems, if arriving by car, please use gates A and E. Department of General Infrastructure Services (GS) GS-SE Group

  15. Patient Telephone Appointment System for High Volume Primary Care Sites

    National Research Council Canada - National Science Library

    Worthington, Francine

    2000-01-01

    ... efficient, timely, convenient, and appropriate access to care. This study follows a Continuous Improvement philosophy of customer satisfaction, quality process improvement, and benchmarking, also known as "idealized process redesign...

  16. Tyramine Hydrochloride Based Label-Free System for Operating Various DNA Logic Gates and a DNA Caliper for Base Number Measurements.

    Science.gov (United States)

    Fan, Daoqing; Zhu, Xiaoqing; Dong, Shaojun; Wang, Erkang

    2017-07-05

    DNA is believed to be a promising candidate for molecular logic computation, and the fluorogenic/colorimetric substrates of G-quadruplex DNAzyme (G4zyme) are broadly used as label-free output reporters of DNA logic circuits. Herein, for the first time, tyramine-HCl (a fluorogenic substrate of G4zyme) is applied to DNA logic computation and a series of label-free DNA-input logic gates, including elementary AND, OR, and INHIBIT logic gates, as well as a two to one encoder, are constructed. Furthermore, a DNA caliper that can measure the base number of target DNA as low as three bases is also fabricated. This DNA caliper can also perform concatenated AND-AND logic computation to fulfil the requirements of sophisticated logic computing. © 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

  17. GATE: Improving the computational efficiency

    Energy Technology Data Exchange (ETDEWEB)

    Staelens, S. [UGent-ELIS, St-Pietersnieuwstraat, 41, B-9000 Gent (Belgium)]. E-mail: steven.staelens@ugent.be; De Beenhouwer, J. [UGent-ELIS, St-Pietersnieuwstraat, 41, B-9000 Gent (Belgium); Kruecker, D. [Institute of Medicine-Forschungszemtrum Juelich, D-52425 Juelich (Germany); Maigne, L. [Departement de Curietherapie-Radiotherapie, Centre Jean Perrin, F-63000 Clermont-Ferrand (France); Rannou, F. [Departamento de Ingenieria Informatica, Universidad de Santiago de Chile, Santiago (Chile); Ferrer, L. [INSERM U601, CHU Nantes, F-44093 Nantes (France); D' Asseler, Y. [UGent-ELIS, St-Pietersnieuwstraat, 41, B-9000 Gent (Belgium); Buvat, I. [INSERM U678 UPMC, CHU Pitie-Salpetriere, F-75634 Paris (France); Lemahieu, I. [UGent-ELIS, St-Pietersnieuwstraat, 41, B-9000 Gent (Belgium)

    2006-12-20

    GATE is a software dedicated to Monte Carlo simulations in Single Photon Emission Computed Tomography (SPECT) and Positron Emission Tomography (PET). An important disadvantage of those simulations is the fundamental burden of computation time. This manuscript describes three different techniques in order to improve the efficiency of those simulations. Firstly, the implementation of variance reduction techniques (VRTs), more specifically the incorporation of geometrical importance sampling, is discussed. After this, the newly designed cluster version of the GATE software is described. The experiments have shown that GATE simulations scale very well on a cluster of homogeneous computers. Finally, an elaboration on the deployment of GATE on the Enabling Grids for E-Science in Europe (EGEE) grid will conclude the description of efficiency enhancement efforts. The three aforementioned methods improve the efficiency of GATE to a large extent and make realistic patient-specific overnight Monte Carlo simulations achievable.

  18. GATE: Improving the computational efficiency

    International Nuclear Information System (INIS)

    Staelens, S.; De Beenhouwer, J.; Kruecker, D.; Maigne, L.; Rannou, F.; Ferrer, L.; D'Asseler, Y.; Buvat, I.; Lemahieu, I.

    2006-01-01

    GATE is a software dedicated to Monte Carlo simulations in Single Photon Emission Computed Tomography (SPECT) and Positron Emission Tomography (PET). An important disadvantage of those simulations is the fundamental burden of computation time. This manuscript describes three different techniques in order to improve the efficiency of those simulations. Firstly, the implementation of variance reduction techniques (VRTs), more specifically the incorporation of geometrical importance sampling, is discussed. After this, the newly designed cluster version of the GATE software is described. The experiments have shown that GATE simulations scale very well on a cluster of homogeneous computers. Finally, an elaboration on the deployment of GATE on the Enabling Grids for E-Science in Europe (EGEE) grid will conclude the description of efficiency enhancement efforts. The three aforementioned methods improve the efficiency of GATE to a large extent and make realistic patient-specific overnight Monte Carlo simulations achievable

  19. Free energy dissipation of the spontaneous gating of a single voltage-gated potassium channel

    Science.gov (United States)

    Wang, Jia-Zeng; Wang, Rui-Zhen

    2018-02-01

    Potassium channels mainly contribute to the resting potential and re-polarizations, with the potassium electrochemical gradient being maintained by the pump Na+/K+-ATPase. In this paper, we construct a stochastic model mimicking the kinetics of a potassium channel, which integrates temporal evolving of the membrane voltage and the spontaneous gating of the channel. Its stationary probability density functions (PDFs) are found to be singular at the boundaries, which result from the fact that the evolving rates of voltage are greater than the gating rates of the channel. We apply PDFs to calculate the power dissipations of the potassium current, the leakage, and the gating currents. On a physical perspective, the essential role of the system is the K+-battery charging the leakage (L-)battery. A part of power will inevitably be dissipated among the process. So, the efficiency of energy transference is calculated.

  20. An Analysis of the Patient Appointing System of the 121st Combat Support Hospital to Determine an Optimal Appointing System

    Science.gov (United States)

    2008-06-01

    Orthopedics/ Podiatry 18 Physical Medicine/Physical Therapy 18 EENT Clinic 19 TRICARE 20 Primary Care Walk-ins to the Emergency Room 20 Statement of...specialty clinics are reviewed below. 17 Orthopedics/ Podiatry Patients needing to be seen by Orthopedics/ Podiatry are referred by primary care

  1. Stock Market Reaction to CEO Appointment – Preliminary Results

    Directory of Open Access Journals (Sweden)

    Katarzyna Byrka-Kita

    2017-06-01

    Full Text Available Purpose: The aim of this paper is to examine shareholders’ reaction to the decision of the supervisory board to appoint a CEO in companies listed on the Warsaw Stock Exchange. Methodology: An event study and the mean-adjusted model were applied. The abnormal returns were measured as the CAAR in the entire (-60, + 60 window and selected sub-windows. Findings: The obtained values of abnormal returns indicate the shareholder’s negative reaction. Throughout the observation window, they oscillate slightly below zero, and in the window (0, +20 they are negative at -1.566%. Irrespective of the observation window, negative abnormal returns were obtained for over half of the observation (52–57%. Therefore, preliminary results indicate the predominance of the information effect over the real one. The decrease in market value as a result of the event may result from an increase in investors’ uncertainty as to the effects of changes in strategy and skills of the new CEO. Originality: The research is a unique one. To date, no one has carried out research into shareholders’ reaction to a CEO appointment in either the Polish or Central and Eastern European capital markets. They primarily bring the value of cognition of shareholders’ behaviour in the analysed event, which is reflected in share prices. They extend the literature on the signalization instruments, i.e. the activities that boards can undertake due to the new information transmitted to the capital market participants and stakeholders. The market reaction to a CEO appointment will without a doubt interest investors; the institutions responsible for supervision (which in the case of Poland is the Financial Oversight Commission and the legislator in charge of regulations that prevent insider trading while promoting corporate disclosure transparency.

  2. The integrity of persons elected, appointed or exercising public functions

    Directory of Open Access Journals (Sweden)

    Agathi Nano

    2017-07-01

    On 17 December 2015, Members of the Albanian Parliament adopt by consensus the constitutional amendments and legislative framework which are necessary to introduce in our country a clear mechanism for the exclusion of criminal offenders from public offices. In this paper we examine regulatory issues relating to the legal framework necessary to guarantee the integrity of public officials, the verification and ascertainment of the prohibition of exercising public functions and the implementation of the prohibitive measures provided for by law no. 138/2015 “On guaranteeing the integrity of the persons elected and/or appointed to, or exercising public functions”, the so called “decriminalisation” law.

  3. Gate-keeping or free access: what do patients prefer: a European study.

    NARCIS (Netherlands)

    Zee, J. van der; Kroneman, M.; Dieteren, W.; Maarse, J.

    2004-01-01

    Background: Health care systems can be subdivided into systems where access to health services is largely unrestricted and systems where specific health care providers (GPs mostly) perform a ‘gate-keeping’ role. Several studies showed that ‘gate-keeping’ health care systems not only seem to be more

  4. Spatially and Temporally Resolved Diagnostics of Dense Sprays Using Gated, Femtosecond, Digital Holography, Phase I

    Data.gov (United States)

    National Aeronautics and Space Administration — This is a proposal to develop a unique, gated, picosecond, digital holography system for characterizing dense particle fields in high pressure combustion...

  5. High fidelity all-microwave controlled-phase gate for superconducting qubits by cavity vacuum displacement

    Science.gov (United States)

    Paik, Hanhee; Zhou, D.; Reed, M. D.; Kirchmair, G.; Frunzio, L.; Girvin, S. M.; Schoelkopf, R. J.

    2013-03-01

    We demonstrate a new all-microwave controlled phase entangling gate for the superconducting qubits in the three-dimensional circuit QED (3D cQED) architecture. The gate exploits the strong coupling between qubits and a cavity, wherein the cavity frequency dispersively shifts depending on the qubit register state. We off-resonantly displace the cavity vacuum state; each computational state evolves a different phase due to the dispersive coupling, yielding a conditional phase. While designed to exploit the advantages of the 3D cQED architecture, the gate requires only dispersive coupling, making the gate applicable to a wide variety of superconducting qubit architectures. We demonstrate 98% gate fidelity evaluated by quantum process tomography, and will discuss how appropriate choices of system parameters could increase this number and how we could minimize the gate infidelity due to measurement induced dephasing and non-adiabatic gate procedure.

  6. Verification and Synthesis of Clock-Gated Circuits

    OpenAIRE

    Dai, Yu-Yun

    2017-01-01

    As system complexity and transistor density increase, the power consumed by digital integrated circuits has become a critical constraint for VLSI design and manufacturing.To reduce dynamic power dissipation, clock-gating synthesis techniques are applied to circuits to prune register updates by modifying the next-state functions of the registers. Hence to verify this kind of synthesis, sequential equivalence checking (SEC) of clock-gated circuits is required.In this thesis, we examine the appl...

  7. Ultrafast, high precision gated integrator

    Energy Technology Data Exchange (ETDEWEB)

    Wang, X.

    1995-01-01

    An ultrafast, high precision gated integrator has been developed by introducing new design approaches that overcome the problems associated with earlier gated integrator circuits. The very high speed is evidenced by the output settling time of less than 50 ns and 20 MHz input pulse rate. The very high precision is demonstrated by the total output offset error of less than 0.2mV and the output droop rate of less than 10{mu}V/{mu}s. This paper describes the theory of this new gated integrator circuit operation. The completed circuit test results are presented.

  8. Gated Treatment Delivery Verification With On-Line Megavoltage Fluoroscopy

    International Nuclear Information System (INIS)

    Tai An; Christensen, James D.; Gore, Elizabeth; Khamene, Ali; Boettger, Thomas; Li, X. Allen

    2010-01-01

    Purpose: To develop and clinically demonstrate the use of on-line real-time megavoltage (MV) fluoroscopy for gated treatment delivery verification. Methods and Materials: Megavoltage fluoroscopy (MVF) image sequences were acquired using a flat panel equipped for MV cone-beam CT in synchrony with the respiratory signal obtained from the Anzai gating device. The MVF images can be obtained immediately before or during gated treatment delivery. A prototype software tool (named RTReg4D) was developed to register MVF images with phase-sequenced digitally reconstructed radiograph images generated from the treatment planning system based on four-dimensional CT. The image registration can be used to reposition the patient before or during treatment delivery. To demonstrate the reliability and clinical usefulness, the system was first tested using a thoracic phantom and then prospectively in actual patient treatments under an institutional review board-approved protocol. Results: The quality of the MVF images for lung tumors is adequate for image registration with phase-sequenced digitally reconstructed radiographs. The MVF was found to be useful for monitoring inter- and intrafractional variations of tumor positions. With the planning target volume contour displayed on the MVF images, the system can verify whether the moving target stays within the planning target volume margin during gated delivery. Conclusions: The use of MVF images was found to be clinically effective in detecting discrepancies in tumor location before and during respiration-gated treatment delivery. The tools and process developed can be useful for gated treatment delivery verification.

  9. Prediction of graduate dietetic internship appointments in Canada.

    Science.gov (United States)

    Beazley, G M

    1991-01-01

    A statistical model of dietetic intern selection was developed from a profile of selection criteria that was obtained in a 1988 survey of Canadian graduate dietetic internship directors. The model was composed of four clusters of variables that resulted from the most frequently used selection criteria: academic performance, work experience, communication skills, and extracurricular activities. Data from a convenience sample of 39 dietetic intern applicants were analyzed, using principal components analysis and discriminant analysis, to test the model's power to predict success in obtaining an internship appointment. In descending order, the criteria with the greatest predictive powers were: academic performance; extracurricular activities; and supervisory, teaching, or instructing types of work experience. The model accounted for 41% of the differences between those who were successful and those who were not successful in obtaining internship appointments in 1989 and correctly classified 30 of 39 subjects. These results provide baseline data on the predictive power of some criteria used for selecting dietetic interns. These findings suggest the need for a replication study with a randomized national sample to crossvalidate the results obtained in this exploratory research.

  10. Men’s Educational Group Appointments in Rural Nicaragua

    Science.gov (United States)

    Campbell, Bruce B.; Gonzalez, Hugo; Campbell, McKenzie; Campbell, Kent

    2016-01-01

    Men’s preventive health and wellness is largely neglected in rural Nicaragua, where a machismo culture prevents men from seeking health care. To address this issue, a men’s educational group appointment model was initiated at a rural health post to increase awareness about hypertension, and to train community health leaders to measure blood pressure. Men’s hypertension workshops were conducted with patient knowledge pretesting, didactic teaching, and posttesting. Pretesting and posttesting performances were recorded, blood pressures were screened, and community leaders were trained to perform sphygmomanometry. An increase in hypertension-related knowledge was observed after every workshop and community health leaders demonstrated proficiency in sphygmomanometry. In addition, several at-risk patients were identified and follow-up care arranged. Men’s educational group appointments, shown to be effective in the United States in increasing patient knowledge and satisfaction, appear to function similarly in a resource-constrained environment and may be an effective mechanism for reaching underserved men in Nicaragua. PMID:27885146

  11. 49 CFR 234.223 - Gate arm.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Gate arm. 234.223 Section 234.223 Transportation... Maintenance Standards § 234.223 Gate arm. Each gate arm, when in the downward position, shall extend across... clearly viewed by approaching highway users. Each gate arm shall start its downward motion not less than...

  12. Demonstration of a Quantum Nondemolition Sum Gate

    DEFF Research Database (Denmark)

    Yoshikawa, J.; Miwa, Y.; Huck, Alexander

    2008-01-01

    The sum gate is the canonical two-mode gate for universal quantum computation based on continuous quantum variables. It represents the natural analogue to a qubit C-NOT gate. In addition, the continuous-variable gate describes a quantum nondemolition (QND) interaction between the quadrature...

  13. Reversible logic gates on Physarum Polycephalum

    International Nuclear Information System (INIS)

    Schumann, Andrew

    2015-01-01

    In this paper, we consider possibilities how to implement asynchronous sequential logic gates and quantum-style reversible logic gates on Physarum polycephalum motions. We show that in asynchronous sequential logic gates we can erase information because of uncertainty in the direction of plasmodium propagation. Therefore quantum-style reversible logic gates are more preferable for designing logic circuits on Physarum polycephalum

  14. A real-time respiration position based passive breath gating equipment for gated radiotherapy: a preclinical evaluation.

    Science.gov (United States)

    Hu, Weigang; Xu, Anjie; Li, Guichao; Zhang, Zhen; Housley, Dave; Ye, Jinsong

    2012-03-01

    To develop a passive gating system incorporating with the real-time position management (RPM) system for the gated radiotherapy. Passive breath gating (PBG) equipment, which consists of a breath-hold valve, a controller mechanism, a mouthpiece kit, and a supporting frame, was designed. A commercial real-time positioning management system was implemented to synchronize the target motion and radiation delivery on a linear accelerator with the patient's breathing cycle. The respiratory related target motion was investigated by using the RPM system for correlating the external markers with the internal target motion while using PBG for passively blocking patient's breathing. Six patients were enrolled in the preclinical feasibility and efficiency study of the PBG system. PBG equipment was designed and fabricated. The PBG can be manually triggered or released to block or unblock patient's breathing. A clinical workflow was outlined to integrate the PBG with the RPM system. After implementing the RPM based PBG system, the breath-hold period can be prolonged to 15-25 s and the treatment delivery efficiency for each field can be improved by 200%-400%. The results from the six patients showed that the diaphragm motion caused by respiration was reduced to less than 3 mm and the position of the diaphragm was reproducible for difference gating periods. A RPM based PBG system was developed and implemented. With the new gating system, the patient's breath-hold time can be extended and a significant improvement in the treatment delivery efficiency can also be achieved.

  15. Cascadable spatial-soliton logic gates.

    Science.gov (United States)

    Blair, S; Wagner, K

    2000-11-10

    The three-terminal spatial-soliton angular-deflection geometry provides the characteristics of an inverting logic gate with gain, and phase-insensitive implementations can be realized by a number of specific nonlinear interactions between orthogonally polarized waves. In particular, numerical simulations of spatial-soliton dragging and collision are used to calculate the transfer functions of inverter and multiple configurations of two-input nor gates and to address their cascadability. These transfer functions converge in cascaded operation and suggest that fan-out greater than 2 with a large noise margin is attainable in a system with standardized signal levels. These results are obtained with the material properties of fused silica and are representative of low-loss Kerr media.

  16. [Establishment and management of electronic appointment library for dental implant patients].

    Science.gov (United States)

    Dong, Zheng-jie; Xu, Kan

    2013-10-01

    To design an excel form which can prompt dental implant patient appointment through color change, which can scientifically manage implant EMR library through appropriate interlinkage and number. An excel form based on operating system Windows XP was designed and software 2003 Microsoft excel was used, which was configured to change color with the passage of time by the use of command "conditional format". An excel form was designed. The color turned to red automatically on the day the patient underwent implant surgery. It turned to yellow when the patient recalled 2 weeks after the first operation, to green when the patient underwent secondary operation. It was designed to be gray when all the procedures of implant restoration was finished. In addition, we could know patients' main implant situation through directly opening his EMR when clicking on his name or number. Dentists can remind the implant patient appointment schedule through color change of an excel form, and can consult the implant patient EMR directly through interlinkage or number.

  17. Gate-set tomography on two coupled transmons

    Science.gov (United States)

    Silva, Marcus; Riste, Diego; Ryan, Colm; Nielsen, Erik; Rudinger, Kenneth; Blume-Kohout, Robin

    Gate set tomography (GST) is a high-accuracy method of reconstructing the evolution of a quantum register. We describe the implementation of GST on two coupled transmon qubits. The ideal gate set includes single-qubit gates and an entangling gate locally equivalent to a CNOT. The analysis shows good agreement with predictions from theoretical models of our system - including the effects of coherent errors, which serve to illustrate important differences between average infidelity and diamond norm error rates. Finally, we describe how to mitigate these errors for improved performance. This effort is supported in part by ARO under contract W911NF-14-C-0048. This document does not contain technology or technical data controlled under either the U.S. ITAR or the U.S. EAR.

  18. Bill Gates vil redde Folkeskolen

    DEFF Research Database (Denmark)

    Fejerskov, Adam Moe

    2014-01-01

    Det amerikanske uddannelsessystem bliver for tiden udsat for hård kritik, ledt an af Microsoft stifteren Bill Gates. Gates har indtil videre brugt 3 mia. kroner på at skabe opbakning til tiltag som præstationslønning af lærere og strømlining af pensum på tværs af alle skoler i landet...

  19. Latest design of gate valves

    Energy Technology Data Exchange (ETDEWEB)

    Kurzhofer, U.; Stolte, J.; Weyand, M.

    1996-12-01

    Babcock Sempell, one of the most important valve manufacturers in Europe, has delivered valves for the nuclear power industry since the beginning of the peaceful application of nuclear power in the 1960s. The latest innovation by Babcock Sempell is a gate valve that meets all recent technical requirements of the nuclear power technology. At the moment in the United States, Germany, Sweden, and many other countries, motor-operated gate and globe valves are judged very critically. Besides the absolute control of the so-called {open_quotes}trip failure,{close_quotes} the integrity of all valve parts submitted to operational forces must be maintained. In case of failure of the limit and torque switches, all valve designs have been tested with respect to the quality of guidance of the gate. The guidances (i.e., guides) shall avoid a tilting of the gate during the closing procedure. The gate valve newly designed by Babcock Sempell fulfills all these characteristic criteria. In addition, the valve has cobalt-free seat hardfacing, the suitability of which has been proven by friction tests as well as full-scale blowdown tests at the GAP of Siemens in Karlstein, West Germany. Babcock Sempell was to deliver more than 30 gate valves of this type for 5 Swedish nuclear power stations by autumn 1995. In the presentation, the author will report on the testing performed, qualifications, and sizing criteria which led to the new technical design.

  20. Robust Deterministic Controlled Phase-Flip Gate and Controlled-Not Gate Based on Atomic Ensembles Embedded in Double-Sided Optical Cavities

    Science.gov (United States)

    Liu, A.-Peng; Cheng, Liu-Yong; Guo, Qi; Zhang, Shou

    2018-02-01

    We first propose a scheme for controlled phase-flip gate between a flying photon qubit and the collective spin wave (magnon) of an atomic ensemble assisted by double-sided cavity quantum systems. Then we propose a deterministic controlled-not gate on magnon qubits with parity-check building blocks. Both the gates can be accomplished with 100% success probability in principle. Atomic ensemble is employed so that light-matter coupling is remarkably improved by collective enhancement. We assess the performance of the gates and the results show that they can be faithfully constituted with current experimental techniques.

  1. How much does a diabetes out-patient appointment actually cost? An argument for PLICS.

    Science.gov (United States)

    Grant, Paul

    2015-01-01

    The national tariff system for clinical processes and procedures aims to put a discrete unit cost on clinical activity. Calculating such costs can be subject to a great deal of local variation and interpretation. Given the rising costs of diabetes the purpose of this paper is to ask the question what does a diabetes outpatient appointment in the UK NHS actually cost? This is important in a time of financial austerity and healthcare rationing because it can be difficult to decipher the attribution of costs within the acute hospital setting. Exploring this question, the author considers the present cost model and analyse in terms of the language of unit model cost; the basic tariff system and how it works in diabetes and looking at internal cost information the author attempts to unbundle the cost to provide a more accurate value for the cost object. One major finding is that costs and overheads are divided arbitrarily as opposed to being distributed on the basis of measured relative consumption. Alternative costing methods are appraised to demonstrate that a patient level episodic costing approach such as patient level information and costing system (PLICS) which incorporates aspects of activity-based costing (ABC) would be far more appropriate. Using time driven ABC (TDABC), a new patient appointment costs £162 for 30 minutes and a follow-up appointment costs £81 for 15 minutes. PLICS has the added benefit of greater financial and clinical transparency and this goes some way towards the holy grail of greater engagement with the doctors delivering clinical care. It would appear that there are different purposes of different costing systems. One can argue that a costing system is there to both contain costs and divide overheads and demonstrate activity. Depending on how data are interpreted costing information can be an agent of enlightenment and behavioural modification for healthcare professionals to show them their direct and indirect costs, their capacity and

  2. A gating grid driver for time projection chambers

    Energy Technology Data Exchange (ETDEWEB)

    Tangwancharoen, S.; Lynch, W.G.; Barney, J.; Estee, J. [National Superconducting Cyclotron Laboratory, Michigan State University, East Lansing, MI 48824 (United States); Department of Physics and Astronomy, Michigan State University, East Lansing, MI 48824 (United States); Shane, R. [National Superconducting Cyclotron Laboratory, Michigan State University, East Lansing, MI 48824 (United States); Tsang, M.B., E-mail: tsang@nscl.msu.edu [National Superconducting Cyclotron Laboratory, Michigan State University, East Lansing, MI 48824 (United States); Department of Physics and Astronomy, Michigan State University, East Lansing, MI 48824 (United States); Zhang, Y. [Department of Physics, Tsinghua University, Beijing 100084 (China); Isobe, T.; Kurata-Nishimura, M. [RIKEN Nishina Center, Hirosawa 2-1, Wako, Saitama 351-0198 (Japan); Murakami, T. [Department of Physics, Kyoto University, Kita-shirakawa, Kyoto 606–8502 (Japan); Xiao, Z.G. [Department of Physics, Tsinghua University, Beijing 100084 (China); Zhang, Y.F. [College of Nuclear Science and Technology, Beijing Normal University, Beijing 100875 (China)

    2017-05-01

    A simple but novel driver system has been developed to operate the wire gating grid of a Time Projection Chamber (TPC). This system connects the wires of the gating grid to its driver via low impedance transmission lines. When the gating grid is open, all wires have the same voltage allowing drift electrons, produced by the ionization of the detector gas molecules, to pass through to the anode wires. When the grid is closed, the wires have alternating higher and lower voltages causing the drift electrons to terminate at the more positive wires. Rapid opening of the gating grid with low pickup noise is achieved by quickly shorting the positive and negative wires to attain the average bias potential with N-type and P-type MOSFET switches. The circuit analysis and simulation software SPICE shows that the driver restores the gating grid voltage to 90% of the opening voltage in less than 0.20 µs, for small values of the termination resistors. When tested in the experimental environment of a time projection chamber larger termination resistors were chosen so that the driver opens the gating grid in 0.35 µs. In each case, opening time is basically characterized by the RC constant given by the resistance of the switches and terminating resistors and the capacitance of the gating grid and its transmission line. By adding a second pair of N-type and P-type MOSFET switches, the gating grid is closed by restoring 99% of the original charges to the wires within 3 µs.

  3. A gating grid driver for time projection chambers

    Science.gov (United States)

    Tangwancharoen, S.; Lynch, W. G.; Barney, J.; Estee, J.; Shane, R.; Tsang, M. B.; Zhang, Y.; Isobe, T.; Kurata-Nishimura, M.; Murakami, T.; Xiao, Z. G.; Zhang, Y. F.; SπRIT Collaboration

    2017-05-01

    A simple but novel driver system has been developed to operate the wire gating grid of a Time Projection Chamber (TPC). This system connects the wires of the gating grid to its driver via low impedance transmission lines. When the gating grid is open, all wires have the same voltage allowing drift electrons, produced by the ionization of the detector gas molecules, to pass through to the anode wires. When the grid is closed, the wires have alternating higher and lower voltages causing the drift electrons to terminate at the more positive wires. Rapid opening of the gating grid with low pickup noise is achieved by quickly shorting the positive and negative wires to attain the average bias potential with N-type and P-type MOSFET switches. The circuit analysis and simulation software SPICE shows that the driver restores the gating grid voltage to 90% of the opening voltage in less than 0.20 μs, for small values of the termination resistors. When tested in the experimental environment of a time projection chamber larger termination resistors were chosen so that the driver opens the gating grid in 0.35 μs. In each case, opening time is basically characterized by the RC constant given by the resistance of the switches and terminating resistors and the capacitance of the gating grid and its transmission line. By adding a second pair of N-type and P-type MOSFET switches, the gating grid is closed by restoring 99% of the original charges to the wires within 3 μs.

  4. NextGen Far-Term Concept Exploration for Integrated Gate-to-Gate Trajectory-Based Operations

    Science.gov (United States)

    Johnson, Sally C.; Barmore, Bryan E.

    2016-01-01

    NASA is currently conducting concept exploration studies toward the definition of a far-term, gate-to-gate concept for Trajectory-Based Operations. This paper presents a basic architectural framework for the far-term concept and discusses some observations about implementation of trajectory-based operations in the National Airspace System. Within the concept, operators and service providers collaboratively negotiate aircraft trajectories, providing agile, optimized, aircraft-specific routing to meet service provider gate-to-gate flow-management constraints and increasing capacity by smoothly and effectively combining flight-deck-based and ground-based metering, merging, and spacing in a mixed-equipage environment. The far-term TBO concept is intended to influence the direction of mid-term TBO research and to inform the definition of stable requirements and standards for TBO communications infrastructure and user equipage.

  5. Hypertension management in primary care: how effective is a telephone recall for patients with low appointment adherence in a practice setting?

    Science.gov (United States)

    Weltermann, Birgitta M; Doost, Sahar Mousa; Kersting, Christine; Gesenhues, Stefan

    2014-10-01

    Studies showed a positive association between appointment adherence and blood pressure control. In randomized-controlled trials blood pressure therapy was improved by recall systems. We analyze the effectiveness of an active telephone recall on blood pressure control for patients with low appointment adherence in regular primary care. This retrospective cohort study analyses all hypertensive patients without any hypertension-related disease (primary prevention) of an academic teaching primary care practice using a structured hypertension management. Blood pressure levels at the beginning of the hypertension management and after 1 year were analyzed. Blood pressure control rates (hypertensive patients were identified. A telephone recall was required in 22 % (n = 92), which was successful in 87 % of patients (n = 80). At the beginning, 66 % of appointment adherent patients had controlled hypertension which increased to 81 % after 1 year. In patients not adhering to appointments the initial blood pressure control rate was 59 % and improved to 74 % after 1 year. Average blood pressure office readings decreased from 141/90 to 136/86 mmHg (p hypertensive patients with low appointment adherence in regular primary care. An active recall can be recommended for other primary care scenarios.

  6. Molecular sensors and molecular logic gates

    International Nuclear Information System (INIS)

    Georgiev, N.; Bojinov, V.

    2013-01-01

    Full text: The rapid grow of nanotechnology field extended the concept of a macroscopic device to the molecular level. Because of this reason the design and synthesis of (supra)-molecular species capable of mimicking the functions of macroscopic devices are currently of great interest. Molecular devices operate via electronic and/or nuclear rearrangements and, like macroscopic devices, need energy to operate and communicate between their elements. The energy needed to make a device work can be supplied as chemical energy, electrical energy, or light. Luminescence is one of the most useful techniques to monitor the operation of molecular-level devices. This fact determinates the synthesis of novel fluorescence compounds as a considerable and inseparable part of nanoscience development. Further miniaturization of semiconductors in electronic field reaches their limit. Therefore the design and construction of molecular systems capable of performing complex logic functions is of great scientific interest now. In semiconductor devices the logic gates work using binary logic, where the signals are encoded as 0 and 1 (low and high current). This process is executable on molecular level by several ways, but the most common are based on the optical properties of the molecule switches encoding the low and high concentrations of the input guest molecules and the output fluorescent intensities with binary 0 and 1 respectively. The first proposal to execute logic operations at the molecular level was made in 1988, but the field developed only five years later when the analogy between molecular switches and logic gates was experimentally demonstrated by de Silva. There are seven basic logic gates: AND, OR, XOR, NOT, NAND, NOR and XNOR and all of them were achieved by molecules, the fluorescence switching as well. key words: fluorescence, molecular sensors, molecular logic gates

  7. Cluster computing software for GATE simulations

    International Nuclear Information System (INIS)

    Beenhouwer, Jan de; Staelens, Steven; Kruecker, Dirk; Ferrer, Ludovic; D'Asseler, Yves; Lemahieu, Ignace; Rannou, Fernando R.

    2007-01-01

    Geometry and tracking (GEANT4) is a Monte Carlo package designed for high energy physics experiments. It is used as the basis layer for Monte Carlo simulations of nuclear medicine acquisition systems in GEANT4 Application for Tomographic Emission (GATE). GATE allows the user to realistically model experiments using accurate physics models and time synchronization for detector movement through a script language contained in a macro file. The downside of this high accuracy is long computation time. This paper describes a platform independent computing approach for running GATE simulations on a cluster of computers in order to reduce the overall simulation time. Our software automatically creates fully resolved, nonparametrized macros accompanied with an on-the-fly generated cluster specific submit file used to launch the simulations. The scalability of GATE simulations on a cluster is investigated for two imaging modalities, positron emission tomography (PET) and single photon emission computed tomography (SPECT). Due to a higher sensitivity, PET simulations are characterized by relatively high data output rates that create rather large output files. SPECT simulations, on the other hand, have lower data output rates but require a long collimator setup time. Both of these characteristics hamper scalability as a function of the number of CPUs. The scalability of PET simulations is improved here by the development of a fast output merger. The scalability of SPECT simulations is improved by greatly reducing the collimator setup time. Accordingly, these two new developments result in higher scalability for both PET and SPECT simulations and reduce the computation time to more practical values

  8. Juan Antonio Rubio appointed as Director-General of CIEMAT

    CERN Multimedia

    2004-01-01

    Juan Antonio Rubio, Head of CERN's ETT unit (Education and Technology Transfer) has been appointed by the Spanish Ministry of Education and Science as the Director General of the Research Centre for Energy, Environment and Technology, CIEMAT. Dr Rubio's career began at the Spanish Nuclear Energy Commission where he held the posts of Investigator, Head of the High Energy Group and Head of Nuclear Physics and High Energy Division. Later, he was named Director of the Department of Basic Investigation and Scientific Director of the CIEMAT. In 1987 he joined CERN as Scientific Adviser to the Director General and Group Leader of the Scientific Assessment Group. Up to now, Dr Rubio has been the Head of the ETT unit, as well as Coordinator for Latin America and Commissioner for the 50th Anniversary of the Organization. He was born on 4 June 1944 in Madrid, and holds a Doctorate in Physical Sciences from the Universidad Complutense de Madrid.

  9. An Integrated Gate Turnaround Management Concept Leveraging Big Data/Analytics for NAS Performance Improvements

    Science.gov (United States)

    Chung, William; Chachad, Girish; Hochstetler, Ronald

    2016-01-01

    The Integrated Gate Turnaround Management (IGTM) concept was developed to improve the gate turnaround performance at the airport by leveraging relevant historical data to support optimization of airport gate operations, which include: taxi to the gate, gate services, push back, taxi to the runway, and takeoff, based on available resources, constraints, and uncertainties. By analyzing events of gate operations, primary performance dependent attributes of these events were identified for the historical data analysis such that performance models can be developed based on uncertainties to support descriptive, predictive, and prescriptive functions. A system architecture was developed to examine system requirements in support of such a concept. An IGTM prototype was developed to demonstrate the concept using a distributed network and collaborative decision tools for stakeholders to meet on time pushback performance under uncertainties.

  10. Comparative study of Colombian Researchers according to data from Google Scholar, ResearchGate and the National System for Measurement Science (Colciencias)

    Energy Technology Data Exchange (ETDEWEB)

    Aguillo, I.; Uribe-Tirado, A.; Lopez Lopez, W.

    2016-07-01

    This paper intends to contextualize the results obtained from the ranking of researchers working at Colombian institutions according to their Google Scholar Citations (GSC) public profiles (1390 with an index equals or larger than 5) with the data from the social network ResearchGate (RG) and the local information provided by Colciencias, the Colombian government agency that publishes a classification of researchers. The results show significant discrepancies between GSC and RG results with the four categories of the classification provided by Colciencias, suggesting that Colciencias should be reconsider its evaluation criteria including new sources and indicators. As the two sources (GSC, RG) and the indicators (H-index, RG-Index) behave very differently regarding disciplines, Colciencias should also take care of the disciplinary assignations, including developing relative indicators by discipline. The potential and importance of Internet platforms for visibility and impact (Science 2.0) should be recognized by the Colombian academic and research organizations. (Author)

  11. Impact of sea level rise on tide gate function.

    Science.gov (United States)

    Walsh, Sean; Miskewitz, Robert

    2013-01-01

    Sea level rise resulting from climate change and land subsidence is expected to severely impact the duration and associated damage resulting from flooding events in tidal communities. These communities must continuously invest resources for the maintenance of existing structures and installation of new flood prevention infrastructure. Tide gates are a common flood prevention structure for low-lying communities in the tidal zone. Tide gates close during incoming tides to prevent inundation from downstream water propagating inland and open during outgoing tides to drain upland areas. Higher downstream mean sea level elevations reduce the effectiveness of tide gates by impacting the hydraulics of the system. This project developed a HEC-RAS and HEC-HMS model of an existing tide gate structure and its upland drainage area in the New Jersey Meadowlands to simulate the impact of rising mean sea level elevations on the tide gate's ability to prevent upstream flooding. Model predictions indicate that sea level rise will reduce the tide gate effectiveness resulting in longer lasting and deeper flood events. The results indicate that there is a critical point in the sea level elevation for this local area, beyond which flooding scenarios become dramatically worse and would have a significantly negative impact on the standard of living and ability to do business in one of the most densely populated areas of America.

  12. Sensory gating in primary insomnia.

    Science.gov (United States)

    Hairston, Ilana S; Talbot, Lisa S; Eidelman, Polina; Gruber, June; Harvey, Allison G

    2010-06-01

    Although previous research indicates that sleep architecture is largely intact in primary insomnia (PI), the spectral content of the sleeping electroencephalographic trace and measures of brain metabolism suggest that individuals with PI are physiologically more aroused than good sleepers. Such observations imply that individuals with PI may not experience the full deactivation of sensory and cognitive processing, resulting in reduced filtering of external sensory information during sleep. To test this hypothesis, gating of sensory information during sleep was tested in participants with primary insomnia (n = 18) and good sleepers (n = 20). Sensory gating was operationally defined as (i) the difference in magnitude of evoked response potentials elicited by pairs of clicks presented during Wake and Stage II sleep, and (ii) the number of K complexes evoked by the same auditory stimulus. During wake the groups did not differ in magnitude of sensory gating. During sleep, sensory gating of the N350 component was attenuated and completely diminished in participants with insomnia. P450, which occurred only during sleep, was strongly gated in good sleepers, and less so in participants with insomnia. Additionally, participants with insomnia showed no stimulus-related increase in K complexes. Thus, PI is potentially associated with impaired capacity to filter out external sensory information, especially during sleep. The potential of using stimulus-evoked K complexes as a biomarker for primary insomnia is discussed.

  13. Predictors of missed appointments in patients referred for congenital or pediatric cardiac magnetic resonance

    Energy Technology Data Exchange (ETDEWEB)

    Lu, Jimmy C.; Dorfman, Adam L. [C.S. Mott Children' s Hospital, Department of Pediatrics and Communicable Diseases, Division of Pediatric Cardiology, University of Michigan Health System, University of Michigan Congenital Heart Center, Ann Arbor, MI (United States); C.S. Mott Children' s Hospital, Department of Radiology, University of Michigan Health System, Section of Pediatric Radiology, Ann Arbor, MI (United States); Lowery, Ray; Yu, Sunkyung [C.S. Mott Children' s Hospital, Department of Pediatrics and Communicable Diseases, Division of Pediatric Cardiology, University of Michigan Health System, University of Michigan Congenital Heart Center, Ann Arbor, MI (United States); Ghadimi Mahani, Maryam [C.S. Mott Children' s Hospital, Department of Radiology, University of Michigan Health System, Section of Pediatric Radiology, Ann Arbor, MI (United States); Agarwal, Prachi P. [University of Michigan Health System, Department of Radiology, Division of Cardiothoracic Radiology, Ann Arbor, MI (United States)

    2017-07-15

    Congenital cardiac magnetic resonance is a limited resource because of scanner and physician availability. Missed appointments decrease scheduling efficiency, have financial implications and represent missed care opportunities. To characterize the rate of missed appointments and identify modifiable predictors. This single-center retrospective study included all patients with outpatient congenital or pediatric cardiac MR appointments from Jan. 1, 2014, through Dec. 31, 2015. We identified missed appointments (no-shows or same-day cancellations) from the electronic medical record. We obtained demographic and clinical factors from the medical record and assessed socioeconomic factors by U.S. Census block data by patient ZIP code. Statistically significant variables (P<0.05) were included into a multivariable analysis. Of 795 outpatients (median age 18.5 years, interquartile range 13.4-27.1 years) referred for congenital cardiac MR, a total of 91 patients (11.4%) missed appointments; 28 (3.5%) missed multiple appointments. Reason for missed appointment could be identified in only 38 patients (42%), but of these, 28 (74%) were preventable or could have been identified prior to the appointment. In multivariable analysis, independent predictors of missed appointments were referral by a non-cardiologist (adjusted odds ratio [AOR] 5.8, P=0.0002), referral for research (AOR 3.6, P=0.01), having public insurance (AOR 2.1, P=0.004), and having scheduled cardiac MR from November to April (AOR 1.8, P=0.01). Demographic factors can identify patients at higher risk for missing appointments. These data may inform initiatives to limit missed appointments, such as targeted education of referring providers and patients. Further data are needed to evaluate the efficacy of potential interventions. (orig.)

  14. Impact of gate fan-in and fan-out limits on optoelectronic digital circuits.

    Science.gov (United States)

    Ji, L; Heuring, V P

    1997-06-10

    The impact of gate fan-in and fan-out limits on digital circuit delay is discussed with a set of benchmark circuits. This research presents the advantages of exploiting the ability of optoelectronic gates to perform both logic operations and optical interconnections with systematic optimization. It is possible for gate-level optical interconnected optoelectronic circuits to compete with their pure silicon counterparts in terms of the combinational circuit delay and system clock rate.

  15. One-way gates based on EPR, GHZ and decoherence-free states of W class

    International Nuclear Information System (INIS)

    Basharov, A.M.; Gorbachev, V.N.; Trubilko, A.I.; Yakovleva, E.S.

    2009-01-01

    The logical gates using quantum measurement as a primitive of quantum computation are considered. It is found that these gates achieved with EPR, GHZ and W entangled states have the same structure, allow encoding the classical information into states of quantum system and can perform any calculations. A particular case of decoherence-free W states is discussed as in this very case the logical gate is decoherence-free.

  16. Comparing Pharmacological Modulation of Sensory Gating in Healthy Humans and Rats

    DEFF Research Database (Denmark)

    Witten, Louise; Bastlund, Jesper Frank; Glenthøj, Birte Y

    2016-01-01

    Sensory gating is the brain's ability to filter out irrelevant information before it reaches high levels of conscious processing. In the current study we aimed to investigate the involvement of the noradrenergic and dopaminergic neurotransmitter systems in sensory gating. Furthermore, we...... gating paradigms in both experiments were identical. In humans, we found significantly reduced P50 suppression following separate administration of reboxetine or haloperidol, while their combined administration did not reach statistical significance compared with placebo. In the rats, we found a similar...

  17. Gate-Keeping and Women\\'s Health Seeking Behaviour in ...

    African Journals Online (AJOL)

    Among the Kassena-Nankana of northern Ghana, compound heads and husbands impede women\\'s prompt access to modern health care. This paper shows that such gate-keeping systems have a negative effect on child survival. To investigate the social construction of compound-based gate-keeping systems, the s relied ...

  18. The effect of the new GMS contract on GP appointment provision in Wales: postal questionnaire survey of practice managers

    Directory of Open Access Journals (Sweden)

    Neal Richard D

    2008-11-01

    Full Text Available Abstract Background Access to health professionals is a key UK NHS priority, and meeting access targets is rewarded through the new General Medical Services (GMS contract in the UK. We sought to determine the current state of appointment provision in Wales and any changes resulting from the need to meet indicators in the new GMS contract. We undertook a postal questionnaire study of practice managers in all general practices in Wales. Findings Valid responses were received from 396/505 (78.4% practice managers. 361 (93.1% practices reported that they had achieved the target for 2004/05. 104 (26% practices reported that they were 100% open access/advanced access. The most frequent changes reported in response to the new GMS contract were offering more open or advanced access slots (237, 60%, more GP phone consultations (167, 42%, introducing a telephone triage system (100, 25%, introducing a minor illness clinic (76, 19%, and employing or training a nurse practitioner (59, 15%. 83% practice managers believed that patients were able to get an appointment at the time they need it either 'all of the time' or 'most of the time', and 70% that patients were able to get an appointment with the GP of choice either 'all of the time' or 'most of the time'. Conclusion This survey has demonstrated the current extent of appointment provision in Wales, and how changes have been driven by incentives. Whether these changes are in the best interests of either patients or doctors, or both, remains to be seen.

  19. Designing single-qutrit quantum gates via tripod adiabatic passage

    Directory of Open Access Journals (Sweden)

    M. Amniat-Talab

    2014-04-01

    Full Text Available In this paper, we use stimulated Raman adiabatic passage technique to implement single-qutrit quantum gates in tripod systems. It is shown by using the Morris-Shore (MS transformation, the six-state problem with 5 pulsed fields can be reduced to a basis that decouples two states from the others. This imposes three pulses not connected to the initial condition with have the same shape. Using this method, the six-state penta-pod system is reduced to a tripod system. We can design single-qutrit quantum gates by ignoring the fragile dynamical phase, and by suitable design of Rabi frequencies of the effective Hamiltonian

  20. New opening hours of the gates

    CERN Multimedia

    GS Department

    2009-01-01

    Please note the new opening hours of the gates as well as the intersites tunnel from the 19 May 2009: GATE A 7h - 19h GATE B 24h/24 GATE C 7h - 9h\t17h - 19h GATE D 8h - 12h\t13h - 16h GATE E 7h - 9h\t17h - 19h Prévessin 24h/24 The intersites tunnel will be opened from 7h30 to 18h non stop. GS-SEM Group Infrastructure and General Services Department

  1. Consumer satisfaction with antipsychotic medication-monitoring appointments: the role of consumer-prescriber communication patterns.

    Science.gov (United States)

    Reich, Catherine M; Hack, Samantha M; Klingaman, Elizabeth A; Brown, Clayton H; Fang, Li Juan; Dixon, Lisa B; Jahn, Danielle R; Kreyenbuhl, Julie A

    2018-06-01

    The study was designed to explore patterns of prescriber communication behaviors as they relate to consumer satisfaction among a serious mental illness sample. Recordings from 175 antipsychotic medication-monitoring appointments between veterans with psychiatric disorders and their prescribers were coded using the Roter Interaction Analysis System (RIAS) for communication behavioral patterns. The frequency of prescriber communication behaviors (i.e., facilitation, rapport, procedural, psychosocial, biomedical, and total utterances) did not reliably predict consumer satisfaction. The ratio of prescriber to consumer utterances did predict consumer satisfaction. Consistent with client-centered care theory, antipsychotic medication consumers were more satisfied with their encounters when their prescriber did not dominate the conversation. Therefore, one potential recommendation from these findings could be for medication prescribers to spend more of their time listening to, rather than speaking with, their SMI consumers.

  2. 78 FR 75948 - Senior Executive Service; Appointment of Members to the Performance Review Board

    Science.gov (United States)

    2013-12-13

    ... Charlotte A. Hayes, Deputy Assistant Secretary for Policy-- appointment expires on 09/30/16 OASAM Naomi M..., Deputy Chief Financial Officer--appointment expires 09/30/14 OFCCP Debra A. Carr, Division of Policy..., 200 Constitution Ave. NW., Washington, DC 20210, telephone: (202) 693-7642. Signed at Washington, DC...

  3. 10 CFR 1045.33 - Appointment of restricted data management official.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 4 2010-01-01 2010-01-01 false Appointment of restricted data management official. 1045... DECLASSIFICATION Generation and Review of Documents Containing Restricted Data and Formerly Restricted Data § 1045.33 Appointment of restricted data management official. (a) Each agency with access to RD or FRD shall...

  4. 38 CFR 13.106 - Investments by court-appointed fiduciaries.

    Science.gov (United States)

    2010-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 1 2010-07-01 2010-07-01 false Investments by court-appointed fiduciaries. 13.106 Section 13.106 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS VETERANS BENEFITS ADMINISTRATION, FIDUCIARY ACTIVITIES § 13.106 Investments by court-appointed...

  5. 5 CFR 315.607 - Noncompetitive appointment of present and former Peace Corps personnel.

    Science.gov (United States)

    2010-01-01

    ... former Peace Corps personnel. 315.607 Section 315.607 Administrative Personnel OFFICE OF PERSONNEL... Appointment Under Special Authorities § 315.607 Noncompetitive appointment of present and former Peace Corps... in service of 3 days or more under section 7(a) of the Peace Corps Act (22 U.S.C. 2506) which...

  6. 26 CFR 20.2041-3 - Powers of appointment created after October 21, 1942.

    Science.gov (United States)

    2010-04-01

    ... power of appointment exercisable only after he reached a certain age, only if he survived another person... possess a general power of appointment as to one-third of the property subject to the power. (d) Releases... contrary, the failure to renounce or disclaim within a reasonable time after learning of its existence will...

  7. 26 CFR 20.2041-1 - Powers of appointment; in general.

    Science.gov (United States)

    2010-04-01

    ... life of an express or implied condition which did not in fact occur. Thus, if in the preceding example...) Definition of “power of appointment”—(1) In general. The term “power of appointment” includes all powers... trustee and appoint himself may be a power of appointment. For example, if under the terms of a trust...

  8. 75 FR 8731 - Proposed Appointment to the National Indian Gaming Commission

    Science.gov (United States)

    2010-02-25

    ... Office of the Secretary of the Interior Proposed Appointment to the National Indian Gaming Commission ACTION: Notice. SUMMARY: The Indian Gaming Regulatory Act provides for a three-person National Indian Gaming Commission. One member, the chairman, is appointed by the President with the advice and consent of...

  9. 77 FR 12908 - Appointment/Reappointment to the National Emergency Medical Services Advisory Council (NEMSAC)

    Science.gov (United States)

    2012-03-02

    ... medical services (EMS) representatives and consumers to provide advice and recommendations regarding EMS.... NHTSA-2012-0027] Appointment/Reappointment to the National Emergency Medical Services Advisory Council... Medical Services Advisory Council (NEMSAC). SUMMARY: NHTSA is soliciting applications for appointment or...

  10. 77 FR 21109 - Senior Executive Service; Appointment of Members to the Performance Review Board

    Science.gov (United States)

    2012-04-09

    ... DEPARTMENT OF LABOR Office of the Secretary Senior Executive Service; Appointment of Members to the Performance Review Board Title 5 U.S.C. 4314(c)(4) provides that Notice of the Appointment of an individual to serve as a member of the Performance Review Board of the Senior Executive Service shall be...

  11. 78 FR 7434 - Medicare Program: Notice of Two Membership Appointments to the Advisory Panel on Hospital...

    Science.gov (United States)

    2013-02-01

    ...] Medicare Program: Notice of Two Membership Appointments to the Advisory Panel on Hospital Outpatient... Panel on Hospital Outpatient Payment (HOP, the Panel). The two new appointments to the Panel will each.... The advice provided by the Panel will be considered as we prepare the annual updates for the hospital...

  12. 77 FR 9255 - Medicare Program: Notice of Six Membership Appointments to the Advisory Panel on Hospital...

    Science.gov (United States)

    2012-02-16

    ...] Medicare Program: Notice of Six Membership Appointments to the Advisory Panel on Hospital Outpatient... Panel on Hospital Outpatient Payment (HOP, the Panel). The six appointments to the 19 member Panel will... Panel will be considered as we prepare the annual updates for the hospital outpatient prospective...

  13. A CNOT gate between multiphoton qubits encoded in two cavities.

    Science.gov (United States)

    Rosenblum, S; Gao, Y Y; Reinhold, P; Wang, C; Axline, C J; Frunzio, L; Girvin, S M; Jiang, Liang; Mirrahimi, M; Devoret, M H; Schoelkopf, R J

    2018-02-13

    Entangling gates between qubits are a crucial component for performing algorithms in quantum computers. However, any quantum algorithm must ultimately operate on error-protected logical qubits encoded in high-dimensional systems. Typically, logical qubits are encoded in multiple two-level systems, but entangling gates operating on such qubits are highly complex and have not yet been demonstrated. Here we realize a controlled NOT (CNOT) gate between two multiphoton qubits in two microwave cavities. In this approach, we encode a qubit in the high-dimensional space of a single cavity mode, rather than in multiple two-level systems. We couple two such encoded qubits together through a transmon, which is driven by an RF pump to apply the gate within 190 ns. This is two orders of magnitude shorter than the decoherence time of the transmon, enabling a high-fidelity gate operation. These results are an important step towards universal algorithms on error-corrected logical qubits.

  14. Pressure locking and thermal binding of gate valves

    Energy Technology Data Exchange (ETDEWEB)

    Kelly, E.M.

    1996-12-01

    Pressure locking and thermal binding represent potential common mode failure mechanisms that can cause safety-related power-operated gate valves to fail in the closed position, thus rendering redundant safety-related systems incapable of performing their safety functions. Supplement 6 to Generic Letter 89-10, {open_quotes}Safety-Related Motor-Operated Gate Valve Testing and Surveillance,{close_quotes} provided an acceptable approach to addressing pressure locking and thermal binding of gate valves. More recently, the NRC has issued Generic Letter 95-07, {open_quotes}Pressure Locking and Thermal Binding of Safety-Related Power-Operated Gate Valves,{close_quotes} to request that licensees take certain actions to ensure that safety-related power-operated gate valves that are susceptible to pressure locking or thermal binding are capable of performing their safety functions within the current licensing bases. Over the past two years, several plants in Region I determined that valves in certain systems were potentially susceptible to pressure locking and thermal binding, and have taken various corrective actions. The NRC Region I Systems Engineering Branch has been actively involved in the inspection of licensee actions in response to the pressure locking and thermal binding issue. Region I continues to maintain an active involvement in this area, including participation with the Office of Nuclear Reactor Regulation in reviewing licensee responses to Generic Letter 95-07.

  15. Nanogranular SiO{sub 2} proton gated silicon layer transistor mimicking biological synapses

    Energy Technology Data Exchange (ETDEWEB)

    Liu, M. J.; Huang, G. S., E-mail: gshuang@fudan.edu.cn, E-mail: pfeng@nju.edu.cn; Guo, Q. L.; Tian, Z. A.; Li, G. J.; Mei, Y. F. [Department of Materials Science, Fudan University, Shanghai 200433 (China); Feng, P., E-mail: gshuang@fudan.edu.cn, E-mail: pfeng@nju.edu.cn; Shao, F.; Wan, Q. [School of Electronic Science and Engineering and Collaborative Innovation Center of Advanced Microstructures, Nanjing University, Nanjing 210093 (China)

    2016-06-20

    Silicon on insulator (SOI)-based transistors gated by nanogranular SiO{sub 2} proton conducting electrolytes were fabricated to mimic synapse behaviors. This SOI-based device has both top proton gate and bottom buried oxide gate. Electrical transfer properties of top proton gate show hysteresis curves different from those of bottom gate, and therefore, excitatory post-synaptic current and paired pulse facilitation (PPF) behavior of biological synapses are mimicked. Moreover, we noticed that PPF index can be effectively tuned by the spike interval applied on the top proton gate. Synaptic behaviors and functions, like short-term memory, and its properties are also experimentally demonstrated in our device. Such SOI-based electronic synapses are promising for building neuromorphic systems.

  16. Nanogranular SiO2 proton gated silicon layer transistor mimicking biological synapses

    International Nuclear Information System (INIS)

    Liu, M. J.; Huang, G. S.; Guo, Q. L.; Tian, Z. A.; Li, G. J.; Mei, Y. F.; Feng, P.; Shao, F.; Wan, Q.

    2016-01-01

    Silicon on insulator (SOI)-based transistors gated by nanogranular SiO 2 proton conducting electrolytes were fabricated to mimic synapse behaviors. This SOI-based device has both top proton gate and bottom buried oxide gate. Electrical transfer properties of top proton gate show hysteresis curves different from those of bottom gate, and therefore, excitatory post-synaptic current and paired pulse facilitation (PPF) behavior of biological synapses are mimicked. Moreover, we noticed that PPF index can be effectively tuned by the spike interval applied on the top proton gate. Synaptic behaviors and functions, like short-term memory, and its properties are also experimentally demonstrated in our device. Such SOI-based electronic synapses are promising for building neuromorphic systems.

  17. Multi-channel normal speed gated integrator in the measurement of the laser scattering light energy

    International Nuclear Information System (INIS)

    Yang Dong; Yu Xiaoqi; Hu Yuanfeng

    2005-01-01

    With the method of integration in a limited time, a Multi-channel normal speed gated integrator based on VXI system has been developed for measuring the signals with changeable pulse width in laser scattering light experiment. It has been tested with signal sources in ICF experiment. In tests, the integral nonlinearity between the integral results of the gated integrator and that of an oscilloscope is less than 1%. In the ICF experiments the maximum error between the integral results of the gated integrator and that of oscilloscope is less than 3% of the full scale range of the gated integrator. (authors)

  18. Rotation gate for a three-level superconducting quantum interference device qubit with resonant interaction

    International Nuclear Information System (INIS)

    Yang, C.-P.; Han Siyuan

    2006-01-01

    We show a way to realize an arbitrary rotation gate in a three-level superconducting quantum interference device (SQUID) qubit using resonant interaction. In this approach, the two logical states of the qubit are represented by the two lowest levels of the SQUID and a higher-energy intermediate level is utilized for the gate manipulation. By considering spontaneous decay from the intermediate level during the gate operation, we present a formula for calculating average fidelity over all possible initial states. Finally, based on realistic system parameters, we show that an arbitrary rotation gate can be achieved with a high fidelity in a SQUID

  19. The anatomy of EU policy-making: Appointing the experts

    Directory of Open Access Journals (Sweden)

    Mark Field

    2013-07-01

    Full Text Available At 38,000, the total number of staff at the European Commission is relatively small for a body representing half a billion citizens. Likewise, the 3,500 strong research and statistical team is modest in size given that it operates across the Directorates General and other services. In order to assist policy-makers, the Commission supplements this research base by using outside expertise to advise at all stages of the policy-making process. For many years, those who observe the European Union’s institutions have recognised that this use of outside expertise to assist with the shaping of policy presents a potential democratic shortfall. The 2001 White Paper on Governance acknowledged that the line between expertise and political authority had become blurred and that, increasingly, the public questioned the independence of expert advice. The following year, the Commission published its first set of guidelines on the collection and use of expertise, listing ‘openness’ as one of three core principles. Despite considerable changes that have occurred in the transparency landscape in the intervening period, the Commission’s commitment to this core principle of expertise remains. This article investigates the measures the Commission introduced specifically to facilitate this openness. Applying a structure-agency approach, the article characterises an expert group as a ‘community of knowledge’ and contrasts the transparency of the Commission’s formal appointment procedures with the less visible but frequently used informal measures through which individuals are identified and approached. Based on a recent and highly relevant case, the article employs data gathered from the near contemporaneous accounts of expert group members and Commission officials. It finds that the reported appointment processes do not reflect the widespread incidence of individuals selected based on previous contact or personal recommendation and argues that this may

  20. Effectiveness of mobile-phone short message service (SMS reminders for ophthalmology outpatient appointments: Observational study

    Directory of Open Access Journals (Sweden)

    Car Josip

    2008-05-01

    Full Text Available Abstract Background Non-attendance for hospital outpatient appointments is a significant problem in many countries. It causes suboptimal use of clinical and administrative staff and financial losses, as well as longer waiting times. The use of Short Message Service (SMS appointment reminders potentially offers a cost-effective and time-efficient strategy to decrease non-attendance and so improve the efficiency of outpatient healthcare delivery. Methods An SMS text message was sent to patients with scheduled appointments between April and September 2006 in a hospital ophthalmology department in London, reminding them of their appointments. This group acted as the intervention group. Controls were patients with scheduled ophthalmology appointments who did not receive an SMS or any alternative reminder. Results During the period of the study, 11.2% (50/447 of patients who received an SMS appointment reminder were non-attenders, compared to 18.1% (1720/9512 who did not receive an SMS reminder. Non-attendance rates were 38% lower in patients who received an SMS reminder than in patients who did not receive a reminder (RR of non-attendance = 0.62; 95% CI = 0.48 – 0.80. Conclusion The use of SMS reminders for ophthalmology outpatient appointments was associated with a reduction of 38% in the likelihood of patients not attending their appointments, compared to no appointment reminder. The use of SMS reminders may also be more cost-effective than traditional appointment reminders and require less labour. These findings should be confirmed with a more rigorous study design before a wider roll-out.

  1. Automated detection of follow-up appointments using text mining of discharge records.

    Science.gov (United States)

    Ruud, Kari L; Johnson, Matthew G; Liesinger, Juliette T; Grafft, Carrie A; Naessens, James M

    2010-06-01

    To determine whether text mining can accurately detect specific follow-up appointment criteria in free-text hospital discharge records. Cross-sectional study. Mayo Clinic Rochester hospitals. Inpatients discharged from general medicine services in 2006 (n = 6481). Textual hospital dismissal summaries were manually reviewed to determine whether the records contained specific follow-up appointment arrangement elements: date, time and either physician or location for an appointment. The data set was evaluated for the same criteria using SAS Text Miner software. The two assessments were compared to determine the accuracy of text mining for detecting records containing follow-up appointment arrangements. Agreement of text-mined appointment findings with gold standard (manual abstraction) including sensitivity, specificity, positive predictive and negative predictive values (PPV and NPV). About 55.2% (3576) of discharge records contained all criteria for follow-up appointment arrangements according to the manual review, 3.2% (113) of which were missed through text mining. Text mining incorrectly identified 3.7% (107) follow-up appointments that were not considered valid through manual review. Therefore, the text mining analysis concurred with the manual review in 96.6% of the appointment findings. Overall sensitivity and specificity were 96.8 and 96.3%, respectively; and PPV and NPV were 97.0 and 96.1%, respectively. of individual appointment criteria resulted in accuracy rates of 93.5% for date, 97.4% for time, 97.5% for physician and 82.9% for location. Text mining of unstructured hospital dismissal summaries can accurately detect documentation of follow-up appointment arrangement elements, thus saving considerable resources for performance assessment and quality-related research.

  2. Dosimetric verification of gated delivery of electron beams using a 2D ion chamber array

    Directory of Open Access Journals (Sweden)

    S A Yoganathan

    2015-01-01

    Full Text Available The purpose of this study was to compare the dosimetric characteristics; such as beam output, symmetry and flatness between gated and non-gated electron beams. Dosimetric verification of gated delivery was carried for all electron beams available on Varian CL 2100CD medical linear accelerator. Measurements were conducted for three dose rates (100 MU/min, 300 MU/min and 600 MU/min and two respiratory motions (breathing period of 4s and 8s. Real-time position management (RPM system was used for the gated deliveries. Flatness and symmetry values were measured using Imatrixx 2D ion chamber array device and the beam output was measured using plane parallel ion chamber. These detector systems were placed over QUASAR motion platform which was programmed to simulate the respiratory motion of target. The dosimetric characteristics of gated deliveries were compared with non-gated deliveries. The flatness and symmetry of all the evaluated electron energies did not differ by more than 0.7 % with respect to corresponding non-gated deliveries. The beam output variation of gated electron beam was less than 0.6 % for all electron energies except for 16 MeV (1.4 %. Based on the results of this study, it can be concluded that Varian CL2100 CD is well suitable for gated delivery of non-dynamic electron beams.

  3. Epileptic Seizures in Patients Following Surgical Treatment of Acute Subdural Hematoma-Incidence, Risk Factors, Patient Outcome, and Development of New Scoring System for Prophylactic Antiepileptic Treatment (GATE-24 score).

    Science.gov (United States)

    Won, Sae-Yeon; Dubinski, Daniel; Herrmann, Eva; Cuca, Colleen; Strzelczyk, Adam; Seifert, Volker; Konczalla, Juergen; Freiman, Thomas M

    2017-05-01

    Clinically evident or subclinical seizures are common manifestations in acute subdural hematoma (aSDH); however, there is a paucity of research investigating the relationship between seizures and aSDH. The purpose of this study is 2-fold: determine incidence and predictors of seizures and then establish a guideline in patients with aSDH to standardize the decision for prophylactic antiepileptic treatment. The author analyzed 139 patients with aSDH treated from 2007 until 2015. Baseline characteristics and clinical findings including Glasgow Coma Scale (GCS) at admission, 24 hours after operation, timing of operation, anticoagulation, and Glasgow Outcome Scale at hospital discharge and after 3 months were analyzed. Multivariate logistic regression analysis was performed to detect independent predictors of seizures, and a scoring system was developed. Of 139 patients, overall incidence of seizures was 38%, preoperatively 16% and postoperatively 24%. Ninety percent of patients with preoperative seizures were seizure free after operation for 3 months. Independent predictors of seizures were GCS <9 (odds ratio [OR] 3.3), operation after 24 hours (OR 2.0), and anticoagulation (OR 2.2). Patients with seizures had a significantly higher rate of unfavorable outcome at hospital discharge (P = 0.001) and in 3-month follow-up (P = 0.002). Furthermore, a score system (GATE-24) was developed. In patients with GCS <14, anticoagulation, or surgical treatment 24 hours after onset, a prophylactic antiepileptic treatment is recommended. Occurrence of seizures affected severity and outcomes after surgical treatment of aSDH. Therefore seizure prophylaxis should be considered in high-risk patients on the basis of the GATE-24 score to promote better clinical outcome. Copyright © 2017 Elsevier Inc. All rights reserved.

  4. Alstom Francis Turbine Ring Gates: from Retrofitting to Commissioning

    Science.gov (United States)

    A, Nguyen P.; G, Labrecque; M-O, Thibault; M, Bergeron; A, Steinhilber; D, Havard

    2014-03-01

    The Ring Gate synchronisation system developed by Alstom is new and patented. It uses hydraulic cylinders connected in pairs by a serial connection. The new hydraulic synchronisation system, when compared to the previous mechanical synchronisation system, has several advantages. It is a compact design; it reduces the number of mechanical components as well as maintenance costs. The new system maintains the Ring Gates robustness. The new approach is an evolution from mechanical to hydraulic synchronization assisted by electronic control. The new synchronization system eliminates several mechanical components that used to add wear and friction and which are usually difficult to adjust during maintenance. Tension chains and sprockets and associated controls are eliminated. Through the position sensors, the redundancy of the ring gate synchronization system makes it predictable and reliable. The electronic control compensates for any variation in operation, for example a leak in the hydraulic system. An emergency closing is possible without the electronic control system due to the stiffness of hydraulic serial connection in the hydraulic cylinder pairs. The Ring Gate can work safely against uneven loads and frictions. The development will be reviewed and its application discussed through commissioning results.

  5. The relevance of electrostatics for scanning-gate microscopy

    Science.gov (United States)

    Schnez, S.; Güttinger, J.; Stampfer, C.; Ensslin, K.; Ihn, T.

    2011-05-01

    Scanning-probe techniques have been developed to extract local information from a given physical system. In particular, conductance maps obtained by means of scanning-gate microscopy (SGM), where a conducting tip of an atomic-force microscope is used as a local and movable gate, seem to present an intuitive picture of the underlying physical processes. Here, we argue that the interpretation of such images is complex and not very intuitive under certain circumstances: scanning a graphene quantum dot (QD) in the Coulomb-blockaded regime, we observe an apparent shift of features in scanning-gate images as a function of gate voltages, which cannot be a real shift of the physical system. Furthermore, we demonstrate the appearance of more than one set of Coulomb rings arising from the graphene QD. We attribute these effects to screening between the metallic tip and the gates. Our results are relevant for SGM on any kind of nanostructure, but are of particular importance for nanostructures that are not covered with a dielectric, e.g. graphene or carbon nanotube structures.

  6. Dynamic gating window for compensation of baseline shift in respiratory-gated radiation therapy

    International Nuclear Information System (INIS)

    Pepin, Eric W.; Wu Huanmei; Shirato, Hiroki

    2011-01-01

    Purpose: To analyze and evaluate the necessity and use of dynamic gating techniques for compensation of baseline shift during respiratory-gated radiation therapy of lung tumors. Methods: Motion tracking data from 30 lung tumors over 592 treatment fractions were analyzed for baseline shift. The finite state model (FSM) was used to identify the end-of-exhale (EOE) breathing phase throughout each treatment fraction. Using duty cycle as an evaluation metric, several methods of end-of-exhale dynamic gating were compared: An a posteriori ideal gating window, a predictive trend-line-based gating window, and a predictive weighted point-based gating window. These methods were evaluated for each of several gating window types: Superior/inferior (SI) gating, anterior/posterior beam, lateral beam, and 3D gating. Results: In the absence of dynamic gating techniques, SI gating gave a 39.6% duty cycle. The ideal SI gating window yielded a 41.5% duty cycle. The weight-based method of dynamic SI gating yielded a duty cycle of 36.2%. The trend-line-based method yielded a duty cycle of 34.0%. Conclusions: Dynamic gating was not broadly beneficial due to a breakdown of the FSM's ability to identify the EOE phase. When the EOE phase was well defined, dynamic gating showed an improvement over static-window gating.

  7. Bill Gates eyes healthcare market.

    Science.gov (United States)

    Dunbar, C

    1995-02-01

    The entrepreneurial spirit is still top in Bill Gates' mind as he look toward healthcare and other growth industries. Microsoft's CEO has not intention of going the way of other large technology companies that became obsolete before they could compete today.

  8. Building framework for nursing scholarship: guidelines for appointment and promotion.

    Science.gov (United States)

    Honig, Judy; Smolowitz, Janice; Larson, Elaine

    2013-01-01

    As nursing academia responds to shifts in nursing education--the emergence of clinically focused doctoral degrees and an emphasis on evidence-based practice, comparative effectiveness, and translational research, nursing scholarship is undergoing transformation. This article outlines guidelines for appointment and promotion that incorporate the academic tripartite and are relevant for all faculty. A clear and equitable pathway for professorial advancement for the both the clinician and research faculty is delineated. Without such clarity and equity, the unique contributions of clinical and research scholars and the synergy that results from these distinctions will not be garnered. Although there is significant overlap in the criteria, there are also distinguishing scholarly activities and outcomes. For each standard at each rank, unique sample criteria of clinical and research scholarship are outlined and the shared scholarly activities that demonstrate the standard. Using an adaptation of Boyer's model, the guidelines incorporate a broadened view of nursing scholarship and offer a framework for nursing academia that recognizes new ways of knowledge. Although recognizing the coexistence of science and practice, these guidelines offer a clear trajectory for advancement in the professorial role that applies an expanded perspective of and provide a framework for nursing scholarship. Copyright © 2013 Elsevier Inc. All rights reserved.

  9. Gate induced drain leakage reduction with analysis of gate fringing field effect on high-κ/metal gate CMOS technology

    Science.gov (United States)

    Jang, Esan; Shin, Sunhae; Jung, Jae Won; Rok Kim, Kyung

    2015-06-01

    We suggest the optimum permittivity for a high-κ/metal gate (HKMG) CMOS structure based on the trade-off characteristics between the fringing field induced barrier lowering (FIBL) and gate induced drain leakage (GIDL). By adopting the high-κ gate dielectric, the GIDL from the band-to-band tunneling at the interface of gate and lightly doped drain (LDD) is suppressed with wide tunneling width owing to the enhanced fringing field, while the FIBL effects is degenerated as the previous reports. These two effects from the gate fringing field are studied extensively to manage the leakage current of HKMG for low power applications.

  10. ``Gate-to-gate`` BJT obtained from the double-gate input JFET to reset charge preamplifiers

    Energy Technology Data Exchange (ETDEWEB)

    Fazzi, A. [Politecnico di Milano (Italy). Dipartimento di Ingegneria Nucleare; Rehak, P. [Brookhaven National Laboratory, Upton, NY 11973 (United States)

    1996-08-01

    A novel charge restoration mechanism to reset charge sensitive preamplifiers is presented. The ``gate-to-gate`` Bipolar Junction Transistor transversal to the input JFET with independent top and bottom gates is exploited as a ``reset transistor`` embodied in the preamplifier input device. The p-n junction between the bottom gate and the channel is forward-biased by a proper feedback loop supplying the necessary restoration current to the input node capacitance through the top gate-channel reversed-biased junction. The continuous reset mode is here analysed with reference to the DC stability, the pulse response and the noise behaviour. Experimental results are reported. (orig.).

  11. The thinnest molecular separation sheet by graphene gates of single-walled carbon nanohorns.

    Science.gov (United States)

    Ohba, Tomonori

    2014-11-25

    Graphene is possibly the thinnest membrane that could be used as a molecular separation gate. Several techniques including absorption, cryogenic distillation, adsorption, and membrane separation have been adopted for constructing separation systems. Molecular separation using graphene as the membrane has been studied because large area synthesis of graphene is possible by chemical vapor deposition. Control of the gate sizes is necessary to achieve high separation performances in graphene membranes. The separation of molecules and ions using graphene and graphene oxide layers could be achieved by the intrinsic defects and defect donation of graphene. However, the controllability of the graphene gates is still under debate because gate size control at the picometer level is inevitable for the fabrication of the thinnest graphene membranes. In this paper, the controlled gate size in the graphene sheets in single-walled carbon nanohorns (NHs) is studied and the molecular separation ability of the graphene sheets is assessed by molecular probing with CO2, O2, N2, CH4, and SF6. Graphene sheets in NHs with different sized gates of 310, 370, and >500 pm were prepared and assessed by molecular probing. The 310 pm-gates in the graphene sheets could separate the molecules tested, whereas weak separation properties were observed for 370 pm-gates. The amount of CO2 that penetrated the 310 pm-gates was more than 35 times larger than that of CH4. These results were supported by molecular dynamics simulations of the penetration of molecules through 300, 400, and 700 pm-gates in graphene sheets. Therefore, a gas separation membrane using a 340-pm-thick graphene sheet has high potential. These findings provide unambiguous evidence of the importance of graphene gates on the picometer level. Control of the gates is the primary challenge for high-performance separation membranes made of graphene.

  12. A new universal gate for low power SoC applications

    Indian Academy of Sciences (India)

    Koomey Jonathan et al 2011). In order to realize ultra low power SoC applications, circuits should be operated with low power dissipating gates. In reality, digital control systems have been designed approximately with either NAND or NOR gates, ...

  13. Image Filtering with Field Programmable Gate Array

    Directory of Open Access Journals (Sweden)

    Arūnas Šlenderis

    2013-05-01

    Full Text Available The research examined the use of field programmable gate arrays (FPGA in image filtering. Experimental and theoretical researches were reviewed. Experiments with Cyclone III family FPGA chip with implemented NIOS II soft processor were considered. Image filtering was achieved with symmetrical and asymmetrical finite impulse response filters with convolution kernel. The system, which was implemented with 3×3 symmetrical filter, which was implemented using the hardware description language, uses 59% of logic elements of the chip and 10 multiplication elements. The system with asymmetrical filter uses the same amount of logic elements and 13 multiplication elements. Both filter systems consume approx. 545 mW of power. The system, which is designed for filter implementation in C language, uses 65% of all logical elements and consumes 729 mW of power.Article in Lithuanian

  14. Quantum walks, quantum gates, and quantum computers

    International Nuclear Information System (INIS)

    Hines, Andrew P.; Stamp, P. C. E.

    2007-01-01

    The physics of quantum walks on graphs is formulated in Hamiltonian language, both for simple quantum walks and for composite walks, where extra discrete degrees of freedom live at each node of the graph. It is shown how to map between quantum walk Hamiltonians and Hamiltonians for qubit systems and quantum circuits; this is done for both single-excitation and multiexcitation encodings. Specific examples of spin chains, as well as static and dynamic systems of qubits, are mapped to quantum walks, and walks on hyperlattices and hypercubes are mapped to various gate systems. We also show how to map a quantum circuit performing the quantum Fourier transform, the key element of Shor's algorithm, to a quantum walk system doing the same. The results herein are an essential preliminary to a Hamiltonian formulation of quantum walks in which coupling to a dynamic quantum environment is included

  15. Fighting Cancer Together: Development and Implementation of Shared Medical Appointments to Standardize and Improve Chemotherapy Education

    Science.gov (United States)

    Prescott, Lauren S.; Dickens, Andrea S.; Guerra, Sandra L.; Tanha, Jila M.; Phillips, Desiree G.; Patel, Katherine T.; Umberson, Katie M.; Lozano, Miguel A.; Lowe, Kathryn B.; Brown, Alaina J.; Taylor, Jolyn S.; Soliman, Pamela T.; Garcia, Elizabeth A.; Levenback, Charles F.; Bodurka, Diane C.

    2015-01-01

    Objective Shared medical appointments offer a novel approach to improve efficiency and quality of care consistent with the goals of the Institute of Medicine. Our objective was to develop and implement a shared medical appointment for gynecologic cancer patients initiating chemotherapy. Methods We first assessed the level of interest in shared medical appointments among our patients and providers through qualitative interviews. Both patients and providers identified pre-chemotherapy as an optimal area to pilot shared medical appointments. We subsequently created a multidisciplinary team comprised of physicians, advanced practice providers, nurses, pharmacists, administrators, health education specialists and members of the Quality Improvement Department to establish a Shared Medical Appointment and Readiness Teaching (SMART) program for all gynecologic oncology patients initiating chemotherapy with platinum- and/or taxane-based regimens. We developed a standardized chemotherapy education presentation and provided patients with a tool kit that consisted of chemotherapy drug education, a guide to managing side effects, advance directives, and center contact information. Results From May 9, 2014 to June 26, 2015, 144 patients participated in 51 SMART visits. The majority of patients had ovarian cancer and were treated with carboplatin/paclitaxel. Surveyed patients reported being highly satisfied with the group visit and would recommend shared medical appointments to other patients. Conclusions This model of care provides patient education within a framework of social support that empowers patients. Shared medical appointments for oncology patients initiating chemotherapy are both feasible and well accepted. PMID:26549108

  16. DATABASE OF MIGRATION AND REPLICATION WITH ORACLE GOLDEN GATE

    Directory of Open Access Journals (Sweden)

    Suharjito Suharjito

    2014-10-01

    Full Text Available The main goal of this research is to analyze and design a database configuration of migration and replication in PT Metro Batavia. Research methodologies used in this research are data collecting, analysis and design model. Data collecting method is conducted with library research and direct survey in the company. Analysis method is conducted by analyzing hangar system, migration and reflection process and the available problems. Design method is conducted by designing a prototype for migration process with the implementation of Oracle SQL Developer and replication process with implementation of Oracle Golden Gate. The result of this research is a prototype for configuration of migration and replication process by using Oracle Golden Gate, which can produce two sets of identical data for the purpose of backup and recovery, and also design a simple tool that is expected to help active-active or active-passive replication process. The conclusion of this research is migration process of MySQL database to Oracle database by using Oracle Golden Gate hasn’t been conducted, because Oracle Golden Gate still has bug related to binary log, so database of migration is conducted by using Oracle Golden Gate. However, replication of bi-directional in between database of Oracle by using Oracle SQL Developer can guarantee data availability and reduce work burden from primary database.

  17. Health Beliefs and Co-morbidities Associated with Appointment-Keeping Behavior Among HCV and HIV/HCV Patients.

    Science.gov (United States)

    Pundhir, Pooja; North, Carol S; Fatunde, Oluwatomilade; Jain, Mamta K

    2016-02-01

    Appointment-keeping behavior is an important requisite for HCV linkage and treatment initiation. In this study we examine what impact hepatitis C (HCV) knowledge and attitudes has on appointment-keeping behavior among a cohort of HCV and HCV/HIV patients. Knowledge scores and attitude scales, obtained from a cross-sectional survey, were correlated with proportion of appointments kept 1 year prior to taking the survey. Independent risk factors for missing appointments were examined by multiple regression analysis. 292 HCV patients completed the survey, and 149 (51%) were co-infected with HIV. HCV patients kept 67.5 ± 17.4% of their total appointments and a similar proportion (67 ± 38.2) of Liver Clinic appointments, but they attended a higher proportion (73 ± 24.4) of Primary Care Clinic appointments. However, certain health beliefs, psychiatric illness, and HIV co-infection were independently associated with lower levels of appointment-keeping behavior. HCV knowledge was not associated with appointment-keeping behavior. Health beliefs, psychiatric illness, and HIV co-infection are associated with missing appointments, but no link between knowledge and appointment keeping behavior is apparent. In order to increase engagement into HCV care, HCV care coordination programs need to focus on addressing health beliefs and providing resources to those at highest risk for missing appointments.

  18. Association of the Presence of Trainees With Outpatient Appointment Times in an Ophthalmology Clinic.

    Science.gov (United States)

    Goldstein, Isaac H; Hribar, Michelle R; Read-Brown, Sarah; Chiang, Michael F

    2018-01-01

    Physicians face pressure to improve clinical efficiency, particularly with electronic health record (EHR) adoption and gradual shifts toward value-based reimbursement models. These pressures are especially pronounced in academic medical centers, where delivery of care must be balanced with medical education. However, the association of the presence of trainees with clinical efficiency in outpatient ophthalmology clinics is not known. To quantify the association of the presence of trainees (residents and fellows) and efficiency in an outpatient ophthalmology clinic. This single-center cohort study was conducted from January 1 through December 31, 2014, at an academic department of ophthalmology. Participants included 49 448 patient appointments with 33 attending physicians and 40 trainees. Presence vs absence of trainees in an appointment or clinic session, as determined by review of the EHR audit log. Patient appointment time, as determined by time stamps in the EHR clinical data warehouse. Linear mixed models were developed to analyze variability among clinicians and patients. Among the 33 study physicians (13 women [39%] and 20 men [61%]; median age, 44 years [interquartile range, 39-53 years]), appointments with trainees were significantly longer than appointments in clinic sessions without trainees (mean [SD], 105.0 [55.7] vs 80.3 [45.4] minutes; P < .001). The presence of a trainee in a clinic session was associated with longer mean appointment time, even in appointments for which the trainee was not present (mean [SD], 87.2 [49.2] vs 80.3 [45.4] minutes; P < .001). Among 33 study physicians, 3 (9%) had shorter mean appointment times when a trainee was present, 1 (3%) had no change, and 29 (88%) had longer mean appointment times when a trainee was present. Linear mixed models showed the presence of a resident was associated with a lengthening of appointment time of 17.0 minutes (95% CI, 15.6-18.5 minutes; P < .001), and the presence of a fellow

  19. The Appointment of a Huntington's Disease Nurse Specialist has Reduced Admission Rate and Improved Admission Quality.

    Science.gov (United States)

    Bourke, David; Finucane, Gregory; Dysart, Jo; Roxburgh, Richard

    2012-01-01

    We aimed to determine if the appointment of a Huntington's disease (HD) nurse specialist has influenced inpatient admission rates and admission quality at Auckland Hospital. We collated HD inpatient admission data for the 32 months before and after her appointment and compared the quality of cognition, mood, speech/swallowing and safety assessments between admissions where the nurse was and was not involved. After the appointment of the HD nurse there was a 51% reduction in average monthly HD admission rates (p = 0.0009). HD admissions specifically related to HD decreased by 54% (p = 0.005). There was also an improvement in the quality of admissions.

  20. Applications of field-programmable gate arrays in scientific research

    CERN Document Server

    Sadrozinski, Hartmut F W

    2011-01-01

    Focusing on resource awareness in field-programmable gate array (FPGA) design, Applications of Field-Programmable Gate Arrays in Scientific Research covers the principle of FPGAs and their functionality. It explores a host of applications, ranging from small one-chip laboratory systems to large-scale applications in ""big science."" The book first describes various FPGA resources, including logic elements, RAM, multipliers, microprocessors, and content-addressable memory. It then presents principles and methods for controlling resources, such as process sequencing, location constraints, and in

  1. Protected quantum computing: interleaving gate operations with dynamical decoupling sequences.

    Science.gov (United States)

    Zhang, Jingfu; Souza, Alexandre M; Brandao, Frederico Dias; Suter, Dieter

    2014-02-07

    Implementing precise operations on quantum systems is one of the biggest challenges for building quantum devices in a noisy environment. Dynamical decoupling attenuates the destructive effect of the environmental noise, but so far, it has been used primarily in the context of quantum memories. Here, we experimentally demonstrate a general scheme for combining dynamical decoupling with quantum logical gate operations using the example of an electron-spin qubit of a single nitrogen-vacancy center in diamond. We achieve process fidelities >98% for gate times that are 2 orders of magnitude longer than the unprotected dephasing time T2.

  2. Imaging of ventilation/perfusion ratio by gated regional spirometry

    International Nuclear Information System (INIS)

    Touya, J.J.; Jones, J.P.; Price, R.R.; Patton, J.A.; Erickson, J.J.; Rollo, F.D.

    1981-01-01

    Gated 133 Xe images of patients rebreathing into a closed system can provide images of the distribution of lung volumes, ventilation and specific ventilation. These have been shown to be accurate, precise, and do not require unusually sophisticated equipment or skills. A mathematical transformation is used to correct the images for lung movement, which does not alter the total number of counts in the image. Perfusion images are gated to remove motion blurring but not transformed. Ventilation/perfusion images showing the distribution of V/Q ratio are then generated from the individual ventilation and perfusion images. (author)

  3. Azobenzene Modified Polymer Electrolyte Membrane for Ion Gating

    Science.gov (United States)

    Piedrahita, Camilo; Mballa, Mireille; He, Ruixuan; Kyu, Thein

    By virtue of ion concentration gradient across cell membranes, neuron cells are highly polarized driving electrical potential difference (e.g., Gibbs law). To regulate and control ion movement, living cells have specific channels with gates that are permeable to cations, enabling or excluding them via charge polarity and size. This mechanism for generating and transmitting signals from one neuron to another controls body movement via brain function. By virtue of trans-cis isomerization, azobenzene derivative (AZO) has been heavily sought for ion-gating in biological cells as a means of signal generation and transmission through nervous systems. In this work, PEM consisted of PEGDA/SCN/LiTFSI was modified with AZO derivatives for gating of lithium ions. At low concentrations of azobenzene of 3 wt Supported by NSF-DMR 1502543.

  4. Gate-keeping in the Age of Information Society

    DEFF Research Database (Denmark)

    Andersen, Kim Normann; Medaglia, Rony; Henriksen, Helle Zinner

    Despite ten years of direct regulation, our study of Danish lower secondary schools shows that they do not provide online access to the GPA for individual public schools (N=1,592). Using Lipsky’s gate-keeping theory, we investigate the lack of data provision as indicator not only of professionals...... in the age of information society where expectations of end-of-gatekeeping by providing accessibility and transparency using information systems has been outnumbered by classical forces of gate-keeping.......Despite ten years of direct regulation, our study of Danish lower secondary schools shows that they do not provide online access to the GPA for individual public schools (N=1,592). Using Lipsky’s gate-keeping theory, we investigate the lack of data provision as indicator not only of professionals...

  5. A real-time respiration position based passive breath gating equipment for gated radiotherapy: A preclinical evaluation

    International Nuclear Information System (INIS)

    Hu Weigang; Xu Anjie; Li Guichao; Zhang Zhen; Housley, Dave; Ye Jinsong

    2012-01-01

    Purpose: To develop a passive gating system incorporating with the real-time position management (RPM) system for the gated radiotherapy. Methods: Passive breath gating (PBG) equipment, which consists of a breath-hold valve, a controller mechanism, a mouthpiece kit, and a supporting frame, was designed. A commercial real-time positioning management system was implemented to synchronize the target motion and radiation delivery on a linear accelerator with the patient's breathing cycle. The respiratory related target motion was investigated by using the RPM system for correlating the external markers with the internal target motion while using PBG for passively blocking patient's breathing. Six patients were enrolled in the preclinical feasibility and efficiency study of the PBG system. Results: PBG equipment was designed and fabricated. The PBG can be manually triggered or released to block or unblock patient's breathing. A clinical workflow was outlined to integrate the PBG with the RPM system. After implementing the RPM based PBG system, the breath-hold period can be prolonged to 15-25 s and the treatment delivery efficiency for each field can be improved by 200%-400%. The results from the six patients showed that the diaphragm motion caused by respiration was reduced to less than 3 mm and the position of the diaphragm was reproducible for difference gating periods. Conclusions: A RPM based PBG system was developed and implemented. With the new gating system, the patient's breath-hold time can be extended and a significant improvement in the treatment delivery efficiency can also be achieved.

  6. Voltage-gated Proton Channels

    Science.gov (United States)

    DeCoursey, Thomas E.

    2014-01-01

    Voltage-gated proton channels, HV1, have vaulted from the realm of the esoteric into the forefront of a central question facing ion channel biophysicists, namely the mechanism by which voltage-dependent gating occurs. This transformation is the result of several factors. Identification of the gene in 2006 revealed that proton channels are homologues of the voltage-sensing domain of most other voltage-gated ion channels. Unique, or at least eccentric, properties of proton channels include dimeric architecture with dual conduction pathways, perfect proton selectivity, a single-channel conductance ~103 smaller than most ion channels, voltage-dependent gating that is strongly modulated by the pH gradient, ΔpH, and potent inhibition by Zn2+ (in many species) but an absence of other potent inhibitors. The recent identification of HV1 in three unicellular marine plankton species has dramatically expanded the phylogenetic family tree. Interest in proton channels in their own right has increased as important physiological roles have been identified in many cells. Proton channels trigger the bioluminescent flash of dinoflagellates, facilitate calcification by coccolithophores, regulate pH-dependent processes in eggs and sperm during fertilization, secrete acid to control the pH of airway fluids, facilitate histamine secretion by basophils, and play a signaling role in facilitating B-cell receptor mediated responses in B lymphocytes. The most elaborate and best-established functions occur in phagocytes, where proton channels optimize the activity of NADPH oxidase, an important producer of reactive oxygen species. Proton efflux mediated by HV1 balances the charge translocated across the membrane by electrons through NADPH oxidase, minimizes changes in cytoplasmic and phagosomal pH, limits osmotic swelling of the phagosome, and provides substrate H+ for the production of H2O2 and HOCl, reactive oxygen species crucial to killing pathogens. PMID:23798303

  7. Quantum logic gates using coherent population trapping states

    Indian Academy of Sciences (India)

    neutral atoms prepared in coherent population trap (CPT) states. It is shown in this paper that such systems can be easily prepared and manipulated and it is possible to build one- qubit and two-qubit gates using them. Since CPT states are 'dark states' of the atom–light interaction, the atoms prepared in such states will not ...

  8. High mobility polymer gated organic field effect transistor using zinc ...

    Indian Academy of Sciences (India)

    Parylene film prepared by chemical vapour deposition was used as the organic gate insulator. ... properties, due to their spatially extended π-electron system ... tronic defects (Gershenson et al 2006). Parylene forms pin hole free, thin conformal transparent coatings with excellent dielectric and mechanical properties ...

  9. Predictors of Missed Research Appointments in a Randomized Placebo-Controlled Trial

    Directory of Open Access Journals (Sweden)

    Stéphanie J.E. Becker

    2014-09-01

     Younger patients with no college education, who believe their health can be controlled, are more likely to miss a research appointment when enrolled in a randomized placebo injection-controlled trial. 

  10. Supreme Court Appointment Process: Roles of the President, Judiciary Committee, and Senate

    National Research Council Canada - National Science Library

    Rutkus, Denis S

    2007-01-01

    .... Under the Constitution, Justices on the Supreme Court receive lifetime appointments. Such job security in the government has been conferred solely on judges and, by constitutional design, helps insure the Court's independence from the President...

  11. Integrated scheduling of tasks and gynecologists to improve patient appointment scheduling : a case study

    NARCIS (Netherlands)

    van de Vrugt, Maartje; Luen-English, Samuel J.; Bastiaansen, W.A.P.; Kleinluchtenbeld, S.; Lardinois, W.T.P.; Pots, M.H.; Schoonbergen, D.H.; Hans, Erwin W.; Hurink, Johann L.; Boucherie, Richardus J.

    Like many hospital departments, the gynecology department of the Jeroen Bosch Hospital experienced difficulties with scheduling outpatient appointments at the medically preferred times. Despite the time invested in creating the schedule, the compliance of the achieved schedules with the preferences

  12. Expanding the National Naval Medical Center's Patient Appointment Call Center: An Analysis

    National Research Council Canada - National Science Library

    Tolentino, Dennis C

    2004-01-01

    ...). Through the Patient Appointment Call Center (PACC), the MTEs at Bethesda and Annapolis are ready for this transition while MTFs at Patuxent River and Quantico are researching potential solutions, including collaborating with PACC...

  13. 12 CFR 1777.28 - Appointment of conservator for a significantly undercapitalized or critically undercapitalized...

    Science.gov (United States)

    2010-01-01

    ... appointment of a conservator would have serious adverse effects on economic conditions of national financial markets or on the financial stability of the housing finance market; and (ii) The public interest would be...

  14. 77 FR 75150 - Appointments to Performance Review Board for Senior Executive Service

    Science.gov (United States)

    2012-12-19

    ... Administration, Department of Education. James M. Kesteloot, Private Citizen. J. Paul M. Laird, Regional Director, North Central Region, Federal Bureau of Prisons, U.S. Department of Justice. All appointments are made...

  15. Preservation of the capacity to appoint a proxy decision maker: implications for dementia research.

    Science.gov (United States)

    Kim, Scott Y H; Karlawish, Jason H; Kim, H Myra; Wall, Ian F; Bozoki, Andrea C; Appelbaum, Paul S

    2011-02-01

    Research involving persons with impaired decision-making capacity (such as persons with Alzheimer disease [AD]) remains ethically challenging, especially when the research involves significant risk. If individuals incapable of consenting to research studies were able to appoint a research proxy, it would allow for an appointed surrogate (rather than a de facto surrogate) to represent the subject. To assess the extent to which persons with AD retain their capacity to appoint a research proxy. Interview study. Academic research. One hundred eighty-eight persons with AD were interviewed for their capacity to appoint a proxy for research and to provide consent to 2 hypothetical research scenarios, a lower-risk randomized clinical trial testing a new drug (drug RCT) and a higher-risk randomized clinical trial testing neurosurgical cell implants using a sham control condition (neurosurgical RCT). Categorical capacity status for each subject was determined by independent videotaped reviews of capacity interviews by 5 experienced psychiatrists. Categorical capacity determinations for the capacity to appoint a research proxy, capacity to consent to a drug RCT, and capacity to consent to a neurosurgical RCT. Data showed that 37.7% (40 of 106) of those deemed incapable of consenting to the drug RCT and 54.8% (86 of 157) of those deemed incapable of consenting to the neurosurgical RCT were found capable of appointing a research proxy. Only 7 of 186 (3.8%) were deemed capable of consenting to the neurosurgical RCT by all 5 psychiatrists. A substantial proportion of persons with AD who were thought incapable of consenting to lower-risk or higher-risk studies have preserved capacity for appointing a research proxy. Because few persons are found to be unequivocally capable of providing independent consent to higher-risk AD research, providing for an appointed surrogate even after the onset of AD, which might best be done in the early stages of the illness, may help address key

  16. Performance Effects of Appointing Other Firms' Executive Directors to Corporate Boards: An Analysis of UK Firms

    OpenAIRE

    Muravyev, Alexander; Talavera, Oleksandr; Weir, Charlie

    2014-01-01

    This paper studies the effect on company performance of appointing non-executive directors that are also executive directors in other firms. The analysis is based on a new panel dataset of UK companies over 2002-2008. Our findings suggest a positive relationship between the presence of these non-executive directors and the accounting performance of the appointing companies. The effect is stronger if these directors are executive directors in firms that are performing well. We also find a posi...

  17. [Requests for emergency appointments with dermatologists in private practice in France: the ETude Urgences en DErmatologie libérale (ET.U.DE) study].

    Science.gov (United States)

    Penso-Assathiany, D; Bourdon-Lanoy, E; Derancourt, C; Roujeau, J-C; Bastuji-Garin, S

    2007-01-01

    work. The score showed good specificity but poor sensitivity and discriminative value. These results suggest that requests for emergency appointments are more frequent than previously suspected (14% of all requests). Physicians considered that emergency appointments within 48 hours were justified for one third of patients. The reasons for consultation and the resulting diagnoses were similar to those seen in emergency hospital consultations. The criteria on which the need for emergency consultation was based were not for the most part dermatologic. The scoring system we established was not sensitive enough to allow reliable pre-selection of patients requiring emergency consultation by telephone.

  18. The Effectiveness of SMS Reminders on Appointment Attendance: a Meta-Analysis.

    Science.gov (United States)

    Boksmati, Nasim; Butler-Henderson, Kerryn; Anderson, Kevin; Sahama, Tony

    2016-04-01

    To identify the efficacy of short message service (SMS) reminders in health care appointment attendance. A systematic review was undertaken to identify studies published between 2005 and 2015 that compared the attendance rates of patients receiving SMS reminders compared to patients not receiving a reminder. Each article was examined for information regarding the study design, sample size, population demographics and intervention methods. A meta-analysis was used to calculate a pooled estimate odds ratio. Twenty-eight (28) studies were included in the review, including 13 (46 %) randomized controlled trials. The pooled odds ratio of the randomized control trials was 1.62 (1.35-1.94). Half of the studies reviewed sent the reminder within 48 h prior to the appointment time, yet no significant subgroups differences with respect to participant age, SMS timing, rate or type, setting or specialty was detectable. All studies, except one with a small sample size, demonstrated a positive OR, indicating SMS reminders were an effective means of improving appointment attendance. There was no significant difference in OR when controlling for when the SMS was sent, the frequency of the reminders or the content of the reminder. SMS appointment reminders are an effective and operative method in improving appointment attendance in a health care setting and this effectiveness has improved over the past 5 years. Further research is required to identify the optimal SMS reminder timing and frequency, specifically in relation to the length of time since the appointment.

  19. Chemotherapy appointment scheduling under uncertainty using mean-risk stochastic integer programming.

    Science.gov (United States)

    Alvarado, Michelle; Ntaimo, Lewis

    2018-03-01

    Oncology clinics are often burdened with scheduling large volumes of cancer patients for chemotherapy treatments under limited resources such as the number of nurses and chairs. These cancer patients require a series of appointments over several weeks or months and the timing of these appointments is critical to the treatment's effectiveness. Additionally, the appointment duration, the acuity levels of each appointment, and the availability of clinic nurses are uncertain. The timing constraints, stochastic parameters, rising treatment costs, and increased demand of outpatient oncology clinic services motivate the need for efficient appointment schedules and clinic operations. In this paper, we develop three mean-risk stochastic integer programming (SIP) models, referred to as SIP-CHEMO, for the problem of scheduling individual chemotherapy patient appointments and resources. These mean-risk models are presented and an algorithm is devised to improve computational speed. Computational results were conducted using a simulation model and results indicate that the risk-averse SIP-CHEMO model with the expected excess mean-risk measure can decrease patient waiting times and nurse overtime when compared to deterministic scheduling algorithms by 42 % and 27 %, respectively.

  20. Instrumentation for Gate Current Noise Measurements on sub-100 nm MOS Transistors

    CERN Document Server

    Gaioni, L; Ratti, L; Re, V; Speziali, V; Traversi, G

    2008-01-01

    This work describes a measuring system that was developed to characterize the gate current noise performances of CMOS devices with minimum feature size in the 100 nm span. These devices play an essential role in the design of present daymixedsignal integrated circuits, because of the advantages associated with the scaling process. The reduction in the gate oxide thickness brought about by CMOS technology downscaling leads to a non-negligible gate current due to direct tunneling phenomena; this current represents a noise source which requires an accurate characterization for optimum analog design. In this paper, two instruments able to perform measurements in two different ranges of gate current values will be discussed. Some of the results of gate current noise characterization will also be presented.

  1. Cognitive mechanisms associated with auditory sensory gating

    Science.gov (United States)

    Jones, L.A.; Hills, P.J.; Dick, K.M.; Jones, S.P.; Bright, P.

    2016-01-01

    Sensory gating is a neurophysiological measure of inhibition that is characterised by a reduction in the P50 event-related potential to a repeated identical stimulus. The objective of this work was to determine the cognitive mechanisms that relate to the neurological phenomenon of auditory sensory gating. Sixty participants underwent a battery of 10 cognitive tasks, including qualitatively different measures of attentional inhibition, working memory, and fluid intelligence. Participants additionally completed a paired-stimulus paradigm as a measure of auditory sensory gating. A correlational analysis revealed that several tasks correlated significantly with sensory gating. However once fluid intelligence and working memory were accounted for, only a measure of latent inhibition and accuracy scores on the continuous performance task showed significant sensitivity to sensory gating. We conclude that sensory gating reflects the identification of goal-irrelevant information at the encoding (input) stage and the subsequent ability to selectively attend to goal-relevant information based on that previous identification. PMID:26716891

  2. Investigation of gating parameter, temperature and density effects on mold filling in the lost foam casting (LFC process by direct observation method

    Directory of Open Access Journals (Sweden)

    A. Sharifi

    2013-03-01

    Full Text Available Mold filling sequence of A356 aluminum alloy was investigated with the aid of direct observation method (photography method. The results show that increase of the foam density causes decrease of the filling rate and increase of the filling time. Foam density has more pronounced effect on mold filling rate rather than pouring temperature. Gating design also affects the profile of molten metal advancement in the mold. The results show that the higher filling rate was obtained with G2 gating than with other gating system. Regarding the mold filling pattern, G3 gating system has more effective contact interface than G2 gating system and has lower filling time. Filling time in G4 gating and G1 gating system are nearly the same.

  3. MCP gated x-ray framing camera

    Science.gov (United States)

    Cai, Houzhi; Liu, Jinyuan; Niu, Lihong; Liao, Hua; Zhou, Junlan

    2009-11-01

    A four-frame gated microchannel plate (MCP) camera is described in this article. Each frame photocathode coated with gold on the MCP is part of a transmission line with open circuit end driven by the gating electrical pulse. The gating pulse is 230 ps in width and 2.5 kV in amplitude. The camera is tested by illuminating its photocathode with ultraviolet laser pulses, 266 nm in wavelength, which shows exposure time as short as 80 ps.

  4. Gating-ML: XML-based gating descriptions in flow cytometry.

    Science.gov (United States)

    Spidlen, Josef; Leif, Robert C; Moore, Wayne; Roederer, Mario; Brinkman, Ryan R

    2008-12-01

    The lack of software interoperability with respect to gating due to lack of a standardized mechanism for data exchange has traditionally been a bottleneck, preventing reproducibility of flow cytometry (FCM) data analysis and the usage of multiple analytical tools. To facilitate interoperability among FCM data analysis tools, members of the International Society for the Advancement of Cytometry (ISAC) Data Standards Task Force (DSTF) have developed an XML-based mechanism to formally describe gates (Gating-ML). Gating-ML, an open specification for encoding gating, data transformations and compensation, has been adopted by the ISAC DSTF as a Candidate Recommendation. Gating-ML can facilitate exchange of gating descriptions the same way that FCS facilitated for exchange of raw FCM data. Its adoption will open new collaborative opportunities as well as possibilities for advanced analyses and methods development. The ISAC DSTF is satisfied that the standard addresses the requirements for a gating exchange standard.

  5. A single nano cantilever as a reprogrammable universal logic gate

    International Nuclear Information System (INIS)

    Chappanda, K N; Ilyas, S; Kazmi, S N R; Younis, M I; Holguin-Lerma, J; Batra, N M; Costa, P M F J

    2017-01-01

    The current transistor-based computing circuits use multiple interconnected transistors to realize a single Boolean logic gate. This leads to higher power requirements and delayed computing. Transistors are not suitable for applications in harsh environments and require complicated thermal management systems due to excessive heat dissipation. Also, transistor circuits lack the ability to dynamically reconfigure their functionality in real time, which is desirable for enhanced computing capability. Further, the miniaturization of transistors to improve computational power is reaching its ultimate physical limits. As a step towards overcoming the limitations of transistor-based computing, here we demonstrate a reprogrammable universal Boolean logic gate based on a nanoelectromechanical cantilever (NC) oscillator. The fundamental XOR, AND, NOR, OR and NOT logic gates are condensed in a single NC, thereby reducing electrical interconnects between devices. The device is dynamically switchable between any logic gates at the same drive frequency without the need for any change in the circuit. It is demonstrated to operate at elevated temperatures minimizing the need for thermal management systems. It has a tunable bandwidth of 5 MHz enabling parallel and dynamically reconfigurable logic device for enhanced computing. (paper)

  6. A single nano cantilever as a reprogrammable universal logic gate

    KAUST Repository

    Chappanda, K. N.

    2017-02-24

    The current transistor-based computing circuits use multiple interconnected transistors to realize a single Boolean logic gate. This leads to higher power requirements and delayed computing. Transistors are not suitable for applications in harsh environments and require complicated thermal management systems due to excessive heat dissipation. Also, transistor circuits lack the ability to dynamically reconfigure their functionality in real time, which is desirable for enhanced computing capability. Further, the miniaturization of transistors to improve computational power is reaching its ultimate physical limits. As a step towards overcoming the limitations of transistor-based computing, here we demonstrate a reprogrammable universal Boolean logic gate based on a nanoelectromechanical cantilever (NC) oscillator. The fundamental XOR, AND, NOR, OR and NOT logic gates are condensed in a single NC, thereby reducing electrical interconnects between devices. The device is dynamically switchable between any logic gates at the same drive frequency without the need for any change in the circuit. It is demonstrated to operate at elevated temperatures minimizing the need for thermal management systems. It has a tunable bandwidth of 5 MHz enabling parallel and dynamically reconfigurable logic device for enhanced computing.

  7. Respiratory gating in cardiac PET: Effects of adenosine and dipyridamole.

    Science.gov (United States)

    Lassen, Martin Lyngby; Rasmussen, Thomas; Christensen, Thomas E; Kjær, Andreas; Hasbak, Philip

    2017-12-01

    Respiratory motion due to breathing during cardiac positron emission tomography (PET) results in spatial blurring and erroneous tracer quantification. Respiratory gating might represent a solution by dividing the PET coincidence dataset into smaller respiratory phase subsets. The aim of our study was to compare the resulting imaging quality by the use of a time-based respiratory gating system in two groups administered either adenosine or dipyridamole as the pharmacological stress agent. Forty-eight patients were randomized to adenosine or dipyridamole cardiac stress 82 RB-PET. Respiratory rates and depths were measured by a respiratory gating system in addition to registering actual respiratory rates. Patients undergoing adenosine stress showed a decrease in measured respiratory rate from initial to later scan phase measurements [12.4 (±5.7) vs 5.6 (±4.7) min -1 , P PET, a dipyridamole stress protocol is recommended as it, compared to adenosine, causes a more uniform respiration and results in a higher frequency of successful respiratory gating and thereby superior imaging quality.

  8. Time complexity and gate complexity

    International Nuclear Information System (INIS)

    Koike, Tatsuhiko; Okudaira, Yosuke

    2010-01-01

    We formulate and investigate the simplest version of time-optimal quantum computation theory (TO-QCT), where the computation time is defined by the physical one and the Hamiltonian contains only one- and two-qubit interactions. This version of TO-QCT is also considered as optimality by sub-Riemannian geodesic length. The work has two aims: One is to develop a TO-QCT itself based on a physically natural concept of time, and the other is to pursue the possibility of using TO-QCT as a tool to estimate the complexity in conventional gate-optimal quantum computation theory (GO-QCT). In particular, we investigate to what extent is true the following statement: Time complexity is polynomial in the number of qubits if and only if gate complexity is also. In the analysis, we relate TO-QCT and optimal control theory (OCT) through fidelity-optimal computation theory (FO-QCT); FO-QCT is equivalent to TO-QCT in the limit of unit optimal fidelity, while it is formally similar to OCT. We then develop an efficient numerical scheme for FO-QCT by modifying Krotov's method in OCT, which has a monotonic convergence property. We implemented the scheme and obtained solutions of FO-QCT and of TO-QCT for the quantum Fourier transform and a unitary operator that does not have an apparent symmetry. The former has a polynomial gate complexity and the latter is expected to have an exponential one which is based on the fact that a series of generic unitary operators has an exponential gate complexity. The time complexity for the former is found to be linear in the number of qubits, which is understood naturally by the existence of an upper bound. The time complexity for the latter is exponential in the number of qubits. Thus, both the targets seem to be examples satisfyng the preceding statement. The typical characteristics of the optimal Hamiltonians are symmetry under time reversal and constancy of one-qubit operation, which are mathematically shown to hold in fairly general situations.

  9. Video-coaching as biofeedback tool to improve gated treatments. Possibilities and limitations

    International Nuclear Information System (INIS)

    Cossmann, Peter H.

    2012-01-01

    For respiratory gated radiotherapy the manufacturers of linear accelerators offer dedicated gating technologies. The video-based Varian RPM Gating system (Varian Medical Systems, Palo Alto/CA, USA) includes in a standard configuration a support tool for regular breathing called audiocoaching. As this approach has limitations regarding direct control of the patient's breathing due to a missing feedback, we designed an additional tool offering videocoaching. In order to evaluate the impact of this additional functionality, we measured parameters defining the image quality of 4D-CT data as well as the treatment duration which is mainly influenced by the patient's limited ability to achieve a stable breathing pattern. (orig.)

  10. Weekday affects attendance rate for medical appointments: large-scale data analysis and implications.

    Directory of Open Access Journals (Sweden)

    David A Ellis

    Full Text Available The financial cost of missed appointments is so great that even a small percentage reduction in Did Not Attend (DNA rate could save significant sums of money. Previous studies have identified many factors that predict DNA rate, including patient age, gender, and transport options. However, it is not obvious how healthcare providers can use this information to improve attendance, as such factors are not under their control. One factor that is under administrative control is appointment scheduling. Here we asked whether DNA rate could be reduced by altering scheduling policy. In Study 1, we examined attendance records for 4,538,294 outpatient hospital appointments across Scotland between January 1st 2008 and December 31st 2010. DNA rate was highest for Mondays (11%, lowest for Fridays (9.7%, and decreased monotonically over the week (Monday-Friday comparison [χ(2(1, N  = 1,585,545  = 722.33, p<0.0001]; Relative Risk Reduction 11.8%. This weekly decline was present for male and female patient groups of all ages, but was steeper for younger age groups. In Study 2, we examined attendance records for 10,895 appointments at a single GP clinic in Glasgow. Here again, DNA rate was highest for Mondays (6.2%, lowest for Fridays (4.2%, and decreased monotonically over the week (Monday-Friday comparison [χ(2(1, N  = 4767  = 9.20, p<0.01]; Relative Risk Reduction 32.3%. In two very different settings, appointments at the beginning of the week were more likely to be missed than appointments at the end of the week. We suggest that DNA rate could be significantly reduced by preferentially loading appointments onto high-attendance days.

  11. The Surface Energy Budget and Precipitation Efficiency for Convective Systems During TOGA, COARE, GATE, SCSMEX and ARM: Cloud-Resolving Model Simulations

    Science.gov (United States)

    Tao, W.-K.; Shie, C.-L.; Johnson, D; Simpson, J.; Starr, David OC. (Technical Monitor)

    2002-01-01

    A two-dimensional version of the Goddard Cumulus Ensemble (GCE) Model is used to simulate convective systems that developed in various geographic locations. Observed large-scale advective tendencies for potential temperature, water vapor mixing ratio, and horizontal momentum derived from field campaigns are used as the main forcing. By examining the surface energy budgets, the model results show that the two largest terms are net condensation (heating/drying) and imposed large-scale forcing (cooling/moistening) for tropical oceanic cases. These two terms arc opposite in sign, however. The contributions by net radiation and latent heat flux to the net condensation vary in these tropical cases, however. For cloud systems that developed over the South China Sea and eastern Atlantic, net radiation (cooling) accounts for about 20% or more of the net condensation. However, short-wave heating and long-wave cooling are in balance with each other for cloud systems over the West Pacific region such that the net radiation is very small. This is due to the thick anvil clouds simulated in the cloud systems over the Pacific region. Large-scale cooling exceeds large-scale moistening in the Pacific and Atlantic cases. For cloud systems over the South China Sea, however, there is more large-scale moistening than cooling even though the cloud systems developed in a very moist environment. though For three cloud systems that developed over a mid-latitude continent, the net radiation and sensible and latent heat fluxes play a much more important role. This means the accurate measurement of surface fluxes and radiation is crucial for simulating these mid-latitude cases.

  12. Special Technology Area Review on Field Programmable Gate Arrays (FPGAs) For Military Applications

    National Research Council Canada - National Science Library

    2005-01-01

    ...) on Field Programmable Gate Arrays (FPGAs) for Military Applications on August 3-4, 2004 at the Naval Postgraduate School in Monterey, California to address issues relevant to the use of this technology in military systems...

  13. Examination of geometric and dosimetric accuracies of gated step-and-shoot intensity modulated radiation therapy

    International Nuclear Information System (INIS)

    Wiersma, R. D.; Xing, L.

    2007-01-01

    Due to the complicated technical nature of gated radiation therapy, electronic and mechanical limitations may affect the precision of delivery. The purpose of this study is to investigate the geometric and dosimetric accuracies of gated step-and-shoot intensity modulated radiation treatments (SS-IMRT). Unique segmental MLC plans are designed, which allow quantitative testing of the gating process. Both ungated and gated deliveries are investigated for different dose sizes, dose rates, and gating window times using a commercial treatment system (Varian Trilogy) together with a respiratory gating system [Varian Real-Time Position Management system]. Radiographic film measurements are used to study the geometric accuracy, where it is found that with both ungated and gated SS-IMRT deliveries the MLC leaf divergence away from planned is less than or equal to the MLC specified leaf tolerance value for all leafs (leaf tolerance being settable from 0.5-5 mm). Nevertheless, due to the MLC controller design, failure to define a specific leaf tolerance value suitable to the SS-IMRT plan can lead to undesired geometric effects, such as leaf motion of up to the maximum 5 mm leaf tolerance value occurring after the beam is turned on. In this case, gating may be advantageous over the ungated case, as it allows more time for the MLC to reach the intended leaf configuration. The dosimetric precision of gated SS-IMRT is investigated using ionization chamber methods. Compared with the ungated case, it is found that gating generally leads to increased dosimetric errors due to the interruption of the ''overshoot phenomena.'' With gating the average timing deviation for intermediate segments is found to be 27 ms, compared to 18 ms for the ungated case. For a plan delivered at 600 MU/min this would correspond to an average segment dose error of ∼0.27 MU and ∼0.18 MU for gated and ungated deliveries, respectively. The maximum dosimetric errors for individual intermediate segments are

  14. Boolean gates on actin filaments

    Energy Technology Data Exchange (ETDEWEB)

    Siccardi, Stefano, E-mail: ssiccardi@2ssas.it [The Unconventional Computing Centre, University of the West of England, Bristol (United Kingdom); Tuszynski, Jack A., E-mail: jackt@ualberta.ca [Department of Oncology, University of Alberta, Edmonton, Alberta (Canada); Adamatzky, Andrew, E-mail: andrew.adamatzky@uwe.ac.uk [The Unconventional Computing Centre, University of the West of England, Bristol (United Kingdom)

    2016-01-08

    Actin is a globular protein which forms long polar filaments in the eukaryotic cytoskeleton. Actin networks play a key role in cell mechanics and cell motility. They have also been implicated in information transmission and processing, memory and learning in neuronal cells. The actin filaments have been shown to support propagation of voltage pulses. Here we apply a coupled nonlinear transmission line model of actin filaments to study interactions between voltage pulses. To represent digital information we assign a logical TRUTH value to the presence of a voltage pulse in a given location of the actin filament, and FALSE to the pulse's absence, so that information flows along the filament with pulse transmission. When two pulses, representing Boolean values of input variables, interact, then they can facilitate or inhibit further propagation of each other. We explore this phenomenon to construct Boolean logical gates and a one-bit half-adder with interacting voltage pulses. We discuss implications of these findings on cellular process and technological applications. - Highlights: • We simulate interaction between voltage pulses using on actin filaments. • We use a coupled nonlinear transmission line model. • We design Boolean logical gates via interactions between the voltage pulses. • We construct one-bit half-adder with interacting voltage pulses.

  15. Gated CT imaging using a free-breathing respiration signal from flow-volume spirometry

    International Nuclear Information System (INIS)

    D'Souza, Warren D.; Kwok, Young; Deyoung, Chad; Zacharapoulos, Nicholas; Pepelea, Mark; Klahr, Paul; Yu, Cedric X.

    2005-01-01

    Respiration-induced tumor motion is known to cause artifacts on free-breathing spiral CT images used in treatment planning. This leads to inaccurate delineation of target volumes on planning CT images. Flow-volume spirometry has been used previously for breath-holds during CT scans and radiation treatments using the active breathing control (ABC) system. We have developed a prototype by extending the flow-volume spirometer device to obtain gated CT scans using a PQ 5000 single-slice CT scanner. To test our prototype, we designed motion phantoms to compare image quality obtained with and without gated CT scan acquisition. Spiral and axial (nongated and gated) CT scans were obtained of phantoms with motion periods of 3-5 s and amplitudes of 0.5-2 cm. Errors observed in the volume estimate of these structures were as much as 30% with moving phantoms during CT simulation. Application of motion-gated CT with active breathing control reduced these errors to within 5%. Motion-gated CT was then implemented in patients and the results are presented for two clinical cases: lung and abdomen. In each case, gated scans were acquired at end-inhalation, end-exhalation in addition to a conventional free-breathing (nongated) scan. The gated CT scans revealed reduced artifacts compared with the conventional free-breathing scan. Differences of up to 20% in the volume of the structures were observed between gated and free-breathing scans. A comparison of the overlap of structures between the gated and free-breathing scans revealed misalignment of the structures. These results demonstrate the ability of flow-volume spirometry to reduce errors in target volumes via gating during CT imaging

  16. Efficiency of respiratory-gated delivery of synchrotron-based pulsed proton irradiation

    International Nuclear Information System (INIS)

    Tsunashima, Yoshikazu; Vedam, Sastry; Dong, Lei; Bues, Martin; Balter, Peter; Smith, Alfred; Mohan, Radhe; Umezawa, Masumi; Sakae, Takeji

    2008-01-01

    Significant differences exist in respiratory-gated proton beam delivery with a synchrotron-based accelerator system when compared to photon therapy with a conventional linear accelerator. Delivery of protons with a synchrotron accelerator is governed by a magnet excitation cycle pattern. Optimal synchronization of the magnet excitation cycle pattern with the respiratory motion pattern is critical to the efficiency of respiratory-gated proton delivery. There has been little systematic analysis to optimize the accelerator's operational parameters to improve gated treatment efficiency. The goal of this study was to estimate the overall efficiency of respiratory-gated synchrotron-based proton irradiation through realistic simulation. Using 62 respiratory motion traces from 38 patients, we simulated respiratory gating for duty cycles of 30%, 20% and 10% around peak exhalation for various fixed and variable magnet excitation patterns. In each case, the time required to deliver 100 monitor units in both non-gated and gated irradiation scenarios was determined. Based on results from this study, the minimum time required to deliver 100 MU was 1.1 min for non-gated irradiation. For respiratory-gated delivery at a 30% duty cycle around peak exhalation, corresponding average delivery times were typically three times longer with a fixed magnet excitation cycle pattern. However, when a variable excitation cycle was allowed in synchrony with the patient's respiratory cycle, the treatment time only doubled. Thus, respiratory-gated delivery of synchrotron-based pulsed proton irradiation is feasible and more efficient when a variable magnet excitation cycle pattern is used

  17. Bioelectronic Interface Connecting Reversible Logic Gates Based on Enzyme and DNA Reactions.

    Science.gov (United States)

    Guz, Nataliia; Fedotova, Tatiana A; Fratto, Brian E; Schlesinger, Orr; Alfonta, Lital; Kolpashchikov, Dmitry M; Katz, Evgeny

    2016-07-18

    It is believed that connecting biomolecular computation elements in complex networks of communicating molecules may eventually lead to a biocomputer that can be used for diagnostics and/or the cure of physiological and genetic disorders. Here, a bioelectronic interface based on biomolecule-modified electrodes has been designed to bridge reversible enzymatic logic gates with reversible DNA-based logic gates. The enzyme-based Fredkin gate with three input and three output signals was connected to the DNA-based Feynman gate with two input and two output signals-both representing logically reversible computing elements. In the reversible Fredkin gate, the routing of two data signals between two output channels was controlled by the control signal (third channel). The two data output signals generated by the Fredkin gate were directed toward two electrochemical flow cells, responding to the output signals by releasing DNA molecules that serve as the input signals for the next Feynman logic gate based on the DNA reacting cascade, producing, in turn, two final output signals. The Feynman gate operated as the controlled NOT gate (CNOT), where one of the input channels controlled a NOT operation on another channel. Both logic gates represented a highly sophisticated combination of input-controlled signal-routing logic operations, resulting in redirecting chemical signals in different channels and performing orchestrated computing processes. The biomolecular reaction cascade responsible for the signal processing was realized by moving the solution from one reacting cell to another, including the reacting flow cells and electrochemical flow cells, which were organized in a specific network mimicking electronic computing circuitries. The designed system represents the first example of high complexity biocomputing processes integrating enzyme and DNA reactions and performing logically reversible signal processing. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  18. Out-patient drug policy by clinical assessment rather than financial constraints? The gate-keeping function of the out-patient drug reimbursement system in The Netherlands

    NARCIS (Netherlands)

    Pronk, Marja H.; Bonsel, Gouke J.

    2004-01-01

    Since 1991, the Dutch Price Reference System (DPRS) has aimed at a growth reduction of out-patient drug costs without loss of medical quality. New drugs are excluded unless they pass legally anchored clinical criteria, i.e. substitutability with accepted drugs (DPRS-list 1a, implies a reimbursement

  19. Determining Gate Count Reliability in a Library Setting

    Directory of Open Access Journals (Sweden)

    Jeffrey Phillips

    2016-09-01

    Full Text Available Objective – Patron counts are a common form of measurement for library assessment. To develop accurate library statistics, it is necessary to determine any differences between various counting devices. A yearlong comparison between card reader turnstiles and laser gate counters in a university library sought to offer a standard percentage of variance and provide suggestions to increase the precision of counts. Methods – The collection of library exit counts identified the differences between turnstile and laser gate counter data. Statistical software helped to eliminate any inaccuracies in the collection of turnstile data, allowing this data set to be the base for comparison. Collection intervals were randomly determined and demonstrated periods of slow, average, and heavy traffic. Results – After analyzing 1,039,766 patron visits throughout a year, the final totals only showed a difference of .43% (.0043 between the two devices. The majority of collection periods did not exceed a difference of 3% between the counting instruments. Conclusion – Turnstiles card readers and laser gate counters provide similar levels of reliability when measuring patron activity. Each system has potential counting inaccuracies, but several methods exist to create more precise totals. Turnstile card readers are capable of offering greater detail involving patron identity, but their high cost makes them inaccessible for libraries with lower budgets. This makes laser gate counters an affordable alternative for reliable patron counting in an academic library.

  20. Optimal appointment scheduling with a stochastic server: Simulation based K-steps look-ahead selection method

    Directory of Open Access Journals (Sweden)

    Changchun Liu

    2018-10-01

    Full Text Available This paper studies the problem of scheduling a finite set of customers with stochastic service times for a single-server system. The objective is to minimize the waiting time of customers, the idle time of the server, and the lateness of the schedule. Because of the NP-hardness of the problem, the optimal schedule is notoriously hard to derive with reasonable computation times. Therefore, we develop a simulation based K-steps look-ahead selection method which can result in nearly optimal schedules within reasonable computation times. Furthermore, we study the different distributed service times, e.g., Exponential, Weibull and lognormal distribution and the results show that the proposed algorithm can obtain better results than the lag order approximation method proposed by Vink et al. (2015 [Vink, W., Kuiper, A., Kemper, B., & Bhulai, S. (2015. Optimal appointment scheduling in continuous time: The lag order approximation method. European Journal of Operational Research, 240(1, 213-219.]. Finally, a realistic appointment scheduling includes experiments to verify the good performance of the proposed method.

  1. Why do those who request smoking treatment fail to attend the first appointment?

    Science.gov (United States)

    Gariti, Peter; Levin, Sarah; Whittingham, Thomas; Barou, Daniela; Xie, Hu; Kampman, Kyle M.; Lynch, Kevin; Halbert, Chanita Hughes; Alterman, Arthur

    2008-01-01

    As part of a larger trial of pharmacological and counseling interventions for light smokers, we performed a telephone-screening interview followed by a scheduled time for an in-person eligibility appointment. 202 of the 407 who screened positive and expressed interest in participation failed to attend the first scheduled appointment. This paper examines person, study and study site characteristics that differentiated those who did follow through from those who did not. The study also examined the self-reported quit rates of both groups 12 weeks later, the time of the study termination. Analyses suggested that non-attendees were more likely to be younger, unemployed, and African American. The most frequently cited reasons for missing the eligibility appointment were work/family obligations, inconvenient appointment times, and personal schedule problems. Those who kept the initial appointment were more likely to report smoking abstinence at 12 weeks. The study has implications for increasing the utilization of potentially effective treatments for smokers. PMID:17931823

  2. A gate drive circuit for gate-turn-off (GTO) devices in series stack

    International Nuclear Information System (INIS)

    Despe, O.

    1999-01-01

    A gate-turn-off (GTO) switch is under development at the Advanced Photon Source as a replacement for a thyratron switch in high power pulsed application. The high voltage in the application requires multiple GTOs connected in series. One component that is critical to the success of GTO operation is the gate drive circuit. The gate drive circuit has to provide fast high-current pulses to the GTO gate for fast turn-on and turn-off. It also has to be able to operate while floating at high voltage. This paper describes a gate drive circuit that meets these requirements

  3. Terahertz amplification in RTD-gated HEMTs with a grating-gate wave coupling topology

    Energy Technology Data Exchange (ETDEWEB)

    Condori Quispe, Hugo O.; Sensale-Rodriguez, Berardi [The University of Utah, Salt Lake City, Utah 84112 (United States); Encomendero-Risco, Jimy J.; Xing, Huili Grace [University of Notre Dame, Notre Dame, Indiana 46556 (United States); Cornell University, Ithaca, New York 14853 (United States)

    2016-08-08

    We theoretically analyze the operation of a terahertz amplifier consisting of a resonant-tunneling-diode gated high-electron-mobility transistor (RTD-gated HEMT) in a grating-gate topology. In these devices, the key element enabling substantial power gain is the efficient coupling of terahertz waves into and out of plasmons in the RTD-gated HEMT channel, i.e., the gain medium, via the grating-gate itself, part of the active device, rather than by an external antenna structure as discussed in previous works, therefore potentially enabling terahertz amplification with associated power gains >40 dB.

  4. Gates Auto Door Car With Lights Modulated

    OpenAIRE

    Lina Carolina; Luyung Dinani, Skom, MMSi

    2002-01-01

    In scientific writing wi ll be explained about automatic gates with modulated headlights, where to find the car lights were adjusted by the relative frequency darker because of this background that the author alleviate human task in performing daily activities by using an automatic gate with the car lights modulated.

  5. Protected gates for topological quantum field theories

    Science.gov (United States)

    Beverland, Michael E.; Buerschaper, Oliver; Koenig, Robert; Pastawski, Fernando; Preskill, John; Sijher, Sumit

    2016-02-01

    We study restrictions on locality-preserving unitary logical gates for topological quantum codes in two spatial dimensions. A locality-preserving operation is one which maps local operators to local operators — for example, a constant-depth quantum circuit of geometrically local gates, or evolution for a constant time governed by a geometrically local bounded-strength Hamiltonian. Locality-preserving logical gates of topological codes are intrinsically fault tolerant because spatially localized errors remain localized, and hence sufficiently dilute errors remain correctable. By invoking general properties of two-dimensional topological field theories, we find that the locality-preserving logical gates are severely limited for codes which admit non-abelian anyons, in particular, there are no locality-preserving logical gates on the torus or the sphere with M punctures if the braiding of anyons is computationally universal. Furthermore, for Ising anyons on the M-punctured sphere, locality-preserving gates must be elements of the logical Pauli group. We derive these results by relating logical gates of a topological code to automorphisms of the Verlinde algebra of the corresponding anyon model, and by requiring the logical gates to be compatible with basis changes in the logical Hilbert space arising from local F-moves and the mapping class group.

  6. Protected gates for topological quantum field theories

    Energy Technology Data Exchange (ETDEWEB)

    Beverland, Michael E.; Pastawski, Fernando; Preskill, John [Institute for Quantum Information and Matter, California Institute of Technology, Pasadena, California 91125 (United States); Buerschaper, Oliver [Dahlem Center for Complex Quantum Systems, Freie Universität Berlin, 14195 Berlin (Germany); Koenig, Robert [Institute for Advanced Study and Zentrum Mathematik, Technische Universität München, 85748 Garching (Germany); Sijher, Sumit [Institute for Quantum Computing and Department of Applied Mathematics, University of Waterloo, Waterloo, Ontario N2L 3G1 (Canada)

    2016-02-15

    We study restrictions on locality-preserving unitary logical gates for topological quantum codes in two spatial dimensions. A locality-preserving operation is one which maps local operators to local operators — for example, a constant-depth quantum circuit of geometrically local gates, or evolution for a constant time governed by a geometrically local bounded-strength Hamiltonian. Locality-preserving logical gates of topological codes are intrinsically fault tolerant because spatially localized errors remain localized, and hence sufficiently dilute errors remain correctable. By invoking general properties of two-dimensional topological field theories, we find that the locality-preserving logical gates are severely limited for codes which admit non-abelian anyons, in particular, there are no locality-preserving logical gates on the torus or the sphere with M punctures if the braiding of anyons is computationally universal. Furthermore, for Ising anyons on the M-punctured sphere, locality-preserving gates must be elements of the logical Pauli group. We derive these results by relating logical gates of a topological code to automorphisms of the Verlinde algebra of the corresponding anyon model, and by requiring the logical gates to be compatible with basis changes in the logical Hilbert space arising from local F-moves and the mapping class group.

  7. Construction of a fuzzy and Boolean logic gates based on DNA.

    Science.gov (United States)

    Zadegan, Reza M; Jepsen, Mette D E; Hildebrandt, Lasse L; Birkedal, Victoria; Kjems, Jørgen

    2015-04-17

    Logic gates are devices that can perform logical operations by transforming a set of inputs into a predictable single detectable output. The hybridization properties, structure, and function of nucleic acids can be used to make DNA-based logic gates. These devices are important modules in molecular computing and biosensing. The ideal logic gate system should provide a wide selection of logical operations, and be integrable in multiple copies into more complex structures. Here we show the successful construction of a small DNA-based logic gate complex that produces fluorescent outputs corresponding to the operation of the six Boolean logic gates AND, NAND, OR, NOR, XOR, and XNOR. The logic gate complex is shown to work also when implemented in a three-dimensional DNA origami box structure, where it controlled the position of the lid in a closed or open position. Implementation of multiple microRNA sensitive DNA locks on one DNA origami box structure enabled fuzzy logical operation that allows biosensing of complex molecular signals. Integrating logic gates with DNA origami systems opens a vast avenue to applications in the fields of nanomedicine for diagnostics and therapeutics. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  8. Two-qubit gate operations in superconducting circuits with strong coupling and weak anharmonicity

    International Nuclear Information System (INIS)

    Lü Xinyou; Ashhab, S; Cui Wei; Wu Rebing; Nori, Franco

    2012-01-01

    We theoretically study the implementation of two-qubit gates in a system of two coupled superconducting qubits. In particular, we analyze two-qubit gate operations under the condition that the coupling strength is comparable with or even larger than the anharmonicity of the qubits. By numerically solving the time-dependent Schrödinger equation under the assumption of negligible decoherence, we obtain the dependence of the two-qubit gate fidelity on the system parameters in the case of both direct and indirect qubit-qubit coupling. Our numerical results can be used to identify the ‘safe’ parameter regime for experimentally implementing two-qubit gates with high fidelity in these systems. (paper)

  9. Multi-gated field emitters for a micro-column

    International Nuclear Information System (INIS)

    Mimura, Hidenori; Kioke, Akifumi; Aoki, Toru; Neo, Yoichiro; Yoshida, Tomoya; Nagao, Masayoshi

    2011-01-01

    We have developed a multi-gated field emitter (FE) such as a quadruple-gated FE with a three-stacked electrode lens and a quintuple-gated FE with a four-stacked electrode lens. Both the FEs can focus the electron beam. However, the quintuple-gated FE has a stronger electron convergence than the quadruple-gated FE, and a beam crossover is clearly observed for the quintuple-gated FE.

  10. Top-gate pentacene-based organic field-effect transistor with amorphous rubrene gate insulator

    Science.gov (United States)

    Hiroki, Mizuha; Maeda, Yasutaka; Ohmi, Shun-ichiro

    2018-02-01

    The scaling of organic field-effect transistors (OFETs) is necessary for high-density integration and for this, OFETs with a top-gate configuration are required. There have been several reports of damageless lithography processes for organic semiconductor or insulator layers. However, it is still difficult to fabricate scaled OFETs with a top-gate configuration. In this study, the lift-off process and the device characteristics of the OFETs with a top-gate configuration utilizing an amorphous (α) rubrene gate insulator were investigated. We have confirmed that α-rubrene shows an insulating property, and its extracted linear mobility was 2.5 × 10‑2 cm2/(V·s). The gate length and width were 10 and 60 µm, respectively. From these results, the OFET with a top-gate configuration utilizing an α-rubrene gate insulator is promising for the high-density integration of scaled OFETs.

  11. Functional importance of T-type voltage-gated calcium channels in the cardiovascular and renal system: news from the world of knockout mice.

    Science.gov (United States)

    Hansen, Pernille B L

    2015-02-15

    Over the years, it has been discussed whether T-type calcium channels Cav3 play a role in the cardiovascular and renal system. T-type channels have been reported to play an important role in renal hemodynamics, contractility of resistance vessels, and pacemaker activity in the heart. However, the lack of highly specific blockers cast doubt on the conclusions. As new T-type channel antagonists are being designed, the roles of T-type channels in cardiovascular and renal pathology need to be elucidated before T-type blockers can be clinically useful. Two types of T-type channels, Cav3.1 and Cav3.2, are expressed in blood vessels, the kidney, and the heart. Studies with gene-deficient mice have provided a way to investigate the Cav3.1 and Cav3.2 channels and their role in the cardiovascular system. This review discusses the results from these knockout mice. Evaluation of the literature leads to the conclusion that Cav3.1 and Cav3.2 channels have important, but different, functions in mice. T-type Cav3.1 channels affect heart rate, whereas Cav3.2 channels are involved in cardiac hypertrophy. In the vascular system, Cav3.2 activation leads to dilation of blood vessels, whereas Cav3.1 channels are mainly suggested to affect constriction. The Cav3.1 channel is also involved in neointima formation following vascular damage. In the kidney, Cav3.1 regulates plasma flow and Cav3.2 plays a role setting glomerular filtration rate. In conclusion, Cav3.1 and Cav3.2 are new therapeutic targets in several cardiovascular pathologies, but the use of T-type blockers should be specifically directed to the disease and to the channel subtype. Copyright © 2015 the American Physiological Society.

  12. Intrafractional Baseline Shift or Drift of Lung Tumor Motion During Gated Radiation Therapy With a Real-Time Tumor-Tracking System

    International Nuclear Information System (INIS)

    Takao, Seishin; Miyamoto, Naoki; Matsuura, Taeko; Onimaru, Rikiya; Katoh, Norio; Inoue, Tetsuya; Sutherland, Kenneth Lee; Suzuki, Ryusuke; Shirato, Hiroki; Shimizu, Shinichi

    2016-01-01

    Purpose: To investigate the frequency and amplitude of baseline shift or drift (shift/drift) of lung tumors in stereotactic body radiation therapy (SBRT), using a real-time tumor-tracking radiation therapy (RTRT) system. Methods and Materials: Sixty-eight patients with peripheral lung tumors were treated with SBRT using the RTRT system. One of the fiducial markers implanted near the tumor was used for the real-time monitoring of the intrafractional tumor motion every 0.033 seconds by the RTRT system. When baseline shift/drift is determined by the system, the position of the treatment couch is adjusted to compensate for the shift/drift. Therefore, the changes in the couch position correspond to the baseline shift/drift in the tumor motion. The frequency and amount of adjustment to the couch positions in the left-right (LR), cranio-caudal (CC), and antero-posterior (AP) directions have been analyzed for 335 fractions administered to 68 patients. Results: The average change in position of the treatment couch during the treatment time was 0.45 ± 2.23 mm (mean ± standard deviation), −1.65 ± 5.95 mm, and 1.50 ± 2.54 mm in the LR, CC, and AP directions, respectively. Overall the baseline shift/drift occurs toward the cranial and posterior directions. The incidence of baseline shift/drift exceeding 3 mm was 6.0%, 15.5%, 14.0%, and 42.1% for the LR, CC, AP, and for the square-root of sum of 3 directions, respectively, within 10 minutes of the start of treatment, and 23.0%, 37.6%, 32.5%, and 71.6% within 30 minutes. Conclusions: Real-time monitoring and frequent adjustments of the couch position and/or adding appropriate margins are suggested to be essential to compensate for possible underdosages due to baseline shift/drift in SBRT for lung cancers.

  13. Restoration of immediately placed implants in 3 appointments: from surgical placement to definitive prostheses.

    Science.gov (United States)

    Ercoli, Carlo; Romano, Paul R; Al Mardini, Majd; Cordaro, Luca

    2006-09-01

    This article describes a comprehensive approach that enables the clinician to place dental implants, and fabricate a provisional prosthesis and a definitive metal-acrylic resin or metal-ceramic fixed complete denture in 3 appointments. This technique allows the practitioner to immediately load the implants with a provisional fixed complete denture at the time of implant placement, to record the relative positions of the implants and soft tissues, the occlusal vertical dimension, maxillomandibular relationship, and tooth position at the second appointment by using the information provided by the provisional fixed denture, and to insert the definitive prosthesis at the third appointment. This technique reduces chair time for both the patient and the clinician, and could ultimately reduce the cost of implant treatment and potentially increase treatment acceptance.

  14. Manipulating the voltage drop in graphene nanojunctions using a gate potential

    DEFF Research Database (Denmark)

    Papior, Nick Rübner; Gunst, Tue; Stradi, Daniele

    2016-01-01

    the impact of electrostatic gating in nanojunctions between graphene electrodes operating at finite bias. Using first principles quantum transport simulations, we show that the voltage drop across \\emph{symmetric} junctions changes dramatically and controllably in gated systems compared to non...... of graphene in the proximity of the Dirac point. Due to the electrostatic gating, each electrode exposes different density of states in the bias window between the two different electrode Fermi energies, thereby leading to a non-symmetry in the voltage drop across the device. This selective pinning is found...

  15. Gate-tunable Phase Transitions in 1T-TaS$_2$

    OpenAIRE

    Yu, Yijun; Yang, Fangyuan; Lu, Xiu Fang; Yan, Ya Jun; Cho, Y. H.; Ma, Liguo; Niu, Xiaohai; Kim, Sejoong; Son, Young-Woo; Feng, Donglai; Li, Shiyan; Cheong, Sang-Wook; Chen, Xian Hui; Zhang, Yuanbo

    2014-01-01

    The ability to tune material properties using gate electric field is at the heart of modern electronic technology. It is also a driving force behind recent advances in two-dimensional systems, such as gate-electric-field induced superconductivity and metal-insulator transition. Here we describe an ionic field-effect transistor (termed "iFET"), which uses gate-controlled lithium ion intercalation to modulate the material property of layered atomic crystal 1T-TaS$_2$. The extreme charge doping ...

  16. Geometric quantum gates in liquid-state NMR based on a cancellation of dynamical phases

    Science.gov (United States)

    Ota, Yukihiro; Goto, Yoshito; Kondo, Yasushi; Nakahara, Mikio

    2009-11-01

    A proposal for applying nonadiabatic geometric phases to quantum computing, called double-loop method [S.-L. Zhu and Z. D. Wang, Phys. Rev. A 67, 022319 (2003)], is demonstrated in a liquid-state nuclear magnetic-resonance quantum computer. Using a spin-echo technique, the original method is modified so that quantum gates are implemented in a standard high-precision nuclear magnetic-resonance system for chemical analysis. We show that a dynamical phase is successfully eliminated and a one-qubit quantum gate is realized although the gate fidelity is not high.

  17. Sidewall gated double well quasi-one-dimensional resonant tunneling transistors

    Science.gov (United States)

    Kolagunta, V. R.; Janes, D. B.; Melloch, M. R.; Youtsey, C.

    1997-12-01

    We present gating characteristics of submicron vertical resonant tunneling transistors in double quantum well heterostructures. Current-voltage characteristics at room temperature and 77 K for devices with minimum feature widths of 0.9 and 0.7 μm are presented and discussed. The evolution of the I-V characteristics with increasing negative gate biases is related to the change in the lateral confinement, with a transition from a large area 2D to a quasi-1D. Even gating of multiple wells and lateral confinement effects observable at 77 K make these devices ideally suited for applications in multi-valued logic systems and low-dimensional structures.

  18. Implementation of one-qubit holonomic rotation gate by adiabatic passage

    Directory of Open Access Journals (Sweden)

    R Nader-Ali

    2010-06-01

    Full Text Available We propose a robust scheme, using tripod stimulated Raman adiabatic passage, to generate one-qubit rotation gate. In this scheme, a four-level atom interacts with three resonant laser pulses and time evolution of the corresponding coherent system is designed such that the rotation gate is implemented at the end of process. Rotation angle in this gate is holonomic and has a geometrical basis in the parameter space. We also explore the effect of spontaneous emission on the population transfer with numerical solution of Schrödinger and Liouville equations.

  19. Construction of a fuzzy and all Boolean logic gates based on DNA

    DEFF Research Database (Denmark)

    M. Zadegan, Reza; Jepsen, Mette D E; Hildebrandt, Lasse

    2015-01-01

    to the operation of the six Boolean logic gates AND, NAND, OR, NOR, XOR, and XNOR. The logic gate complex is shown to work also when implemented in a three-dimensional DNA origami box structure, where it controlled the position of the lid in a closed or open position. Implementation of multiple microRNA sensitive...... DNA locks on one DNA origami box structure enabled fuzzy logical operation that allows biosensing of complex molecular signals. Integrating logic gates with DNA origami systems opens a vast avenue to applications in the fields of nanomedicine for diagnostics and therapeutics....

  20. Toward Sustainable Management: 2D Modelling of a Self-Cleaning System to Improve Geometry in Front of the Flushing Gate

    Directory of Open Access Journals (Sweden)

    Luis Carlos Ruiloba

    2018-03-01

    Full Text Available This paper aims to show how numerical modelling based on 2D SWE can be used to analyze the cleaning effectiveness of flushing waves in storm tanks. The case study under consideration is an existing storm tank located in Badalona, a municipality of Barcelona, Spain. Storm tank cleaning systems are critical features that must be carefully addressed. If not appropriately addressed, operation and maintenance work costs can drastically increase. There are numerous currently available technologies for cleaning storage tanks. However, no specific guide on this field has been identified. References are provided by the manufacturers through their commercial catalogues. Generally, this information is not based on experimental or numerical experiences or results have not been published in the literature of scientific papers. In this study, a public domain software (IBER was used to develop 2D hydraulic analysis of the selected tank. The results obtained show how the phenomenon of recirculation is acting in some areas of the lane. This implies a dissipation of energy, thus causing difficulties in terms of cleaning procedures. Furthermore, two new scenarios have been tested to determine how a different lane width might affect hydrodynamic behavior. A newly suggested geometry for the existing lane of the tank is proposed by using the numerical modeling software. The proposed geometry in the current pilot tank achieves higher velocities and avoids recirculation areas. The results demonstrate that numerical modelling of these types of processes is possible with the computer models available (commercial codes and can be used to optimize cleaning system design.

  1. Mechanism of electromechanical coupling in voltage-gated potassium channels

    Directory of Open Access Journals (Sweden)

    Rikard eBlunck

    2012-09-01

    Full Text Available Voltage-gated ion channels play a central role in the generation of action potentials in the nervous system. They are selective for one type of ion – sodium, calcium or potassium. Voltage-gated ion channels are composed of a central pore that allows ions to pass through the membrane and four peripheral voltage sensing domains that respond to changes in the membrane potential. Upon depolarization, voltage sensors in voltage-gated potassium channels (Kv undergo conformational changes driven by positive charges in the S4 segment and aided by pairwise electrostatic interactions with the surrounding voltage sensor. Structure-function relations of Kv channels have been investigated in detail, and the resulting models on the movement of the voltage sensors now converge to a consensus; the S4 segment undergoes a combined movement of rotation, tilt and vertical displacement in order to bring 3-4 e+ each through the electric field focused in this region. Nevertheless, the mechanism by which the voltage sensor movement leads to pore opening, the electromechanical coupling, is still not fully understood. Thus, recently, electromechanical coupling in different Kv channels has been investigated with a multitude of techniques including electrophysiology, 3D crystal structures, fluorescence spectroscopy and molecular dynamics simulations. Evidently, the S4-S5 linker, the covalent link between the voltage sensor and pore, plays a crucial role. The linker transfers the energy from the voltage sensor movement to the pore domain via an interaction with the S6 C-termini, which are pulled open during gating. In addition, other contact regions have been proposed. This review aims to provide (i an in-depth comparison of the molecular mechanisms of electromechanical coupling in different Kv channels; (ii insight as to how the voltage sensor and pore domain influence one another; and (iii theoretical predictions on the movement of the cytosolic face of the KV channels

  2. Simulation of 50-nm Gate Graphene Nanoribbon Transistors

    Directory of Open Access Journals (Sweden)

    Cedric Nanmeni Bondja

    2016-01-01

    Full Text Available An approach to simulate the steady-state and small-signal behavior of GNR MOSFETs (graphene nanoribbon metal-semiconductor-oxide field-effect transistor is presented. GNR material parameters and a method to account for the density of states of one-dimensional systems like GNRs are implemented in a commercial device simulator. This modified tool is used to calculate the current-voltage characteristics as well the cutoff frequency fT and the maximum frequency of oscillation fmax of GNR MOSFETs. Exemplarily, we consider 50-nm gate GNR MOSFETs with N = 7 armchair GNR channels and examine two transistor configurations. The first configuration is a simplified MOSFET structure with a single GNR channel as usually studied by other groups. Furthermore, and for the first time in the literature, we study in detail a transistor structure with multiple parallel GNR channels and interribbon gates. It is shown that the calculated fT of GNR MOSFETs is significantly lower than that of GFETs (FET with gapless large-area graphene channel with comparable gate length due to the mobility degradation in GNRs. On the other hand, GNR MOSFETs show much higher fmax compared to experimental GFETs due the semiconducting nature of the GNR channels and the resulting better saturation of the drain current. Finally, it is shown that the gate control in FETs with multiple parallel GNR channels is improved while the cutoff frequency is degraded compared to single-channel GNR MOSFETs due to parasitic capacitances of the interribbon gates.

  3. Materials Fundamentals of Gate Dielectrics

    CERN Document Server

    Demkov, Alexander A

    2006-01-01

    This book presents materials fundamentals of novel gate dielectrics that are being introduced into semiconductor manufacturing to ensure the continuous scalling of the CMOS devices. This is a very fast evolving field of research so we choose to focus on the basic understanding of the structure, thermodunamics, and electronic properties of these materials that determine their performance in device applications. Most of these materials are transition metal oxides. Ironically, the d-orbitals responsible for the high dielectric constant cause sever integration difficulties thus intrinsically limiting high-k dielectrics. Though new in the electronics industry many of these materials are wel known in the field of ceramics, and we describe this unique connection. The complexity of the structure-property relations in TM oxides makes the use of the state of the art first-principles calculations necessary. Several chapters give a detailed description of the modern theory of polarization, and heterojunction band discont...

  4. Two-Input Enzymatic Logic Gates Made Sigmoid by Modifications of the Biocatalytic Reaction Cascades

    Energy Technology Data Exchange (ETDEWEB)

    Zavalov, Oleksandr [Clarkson University, Potsdam, NY; Bocharova, Vera [ORNL; Halamek, Jan [Clarkson University, Potsdam, NY; Halamkova, Lenka [Clarkson University, Potsdam, NY; Korkmaz, Sevim [Clarkson University, Potsdam, NY; Arugula, Mary [University of Utah; Chinnapareddy, Soujanya [Clarkson University, Potsdam, NY; Katz, Evgeny [Clarkson University, Potsdam, NY; Privman, Vladimir [Clarkson University, Potsdam, NY

    2012-01-01

    Computing based on biochemical processes is a newest rapidly developing field of unconventional information and signal processing. In this paper we present results of our research in the field of biochemical computing and summarize the obtained numerical and experimental data for implementations of the standard two-input OR and AND gates with double-sigmoid shape of the output signal. This form of response was obtained as a function of the two inputs in each of the realized biochemical systems. The enzymatic gate processes in the first system were activated with two chemical inputs and resulted in optically detected chromogen oxidation, which happens when either one or both of the inputs are present. In this case, the biochemical system is functioning as the OR gate. We demonstrate that the addition of a filtering biocatalytic process leads to a considerable reduction of the noise transmission factor and the resulting gate response has sigmoid shape in both inputs. The second system was developed for functioning as an AND gate, where the output signal was activated only by a simultaneous action of two enzymatic biomarkers. This response can be used as an indicator of liver damage, but only if both of these of the inputs are present at their elevated, pathophysiological values of concentrations. A kinetic numerical model was developed and used to estimate the range of parameters for which the experimentally realized logic gate is close to optimal. We also analyzed the system to evaluate its noise-handling properties.

  5. A Prospective Cohort Study of Gated Stereotactic Liver Radiation Therapy Using Continuous Internal Electromagnetic Motion Monitoring.

    Science.gov (United States)

    Worm, Esben S; Høyer, Morten; Hansen, Rune; Larsen, Lars P; Weber, Britta; Grau, Cai; Poulsen, Per R

    2018-02-13

    Intrafraction motion can compromise the treatment accuracy in liver stereotactic body radiation therapy (SBRT). Respiratory gating can improve treatment delivery; however, gating based on external motion surrogates is inaccurate. The present study reports the use of Calypso-based internal electromagnetic motion monitoring for gated liver SBRT. Fifteen patients were included in a study of 3-fraction respiratory gated liver SBRT guided by 3 implanted electromagnetic transponders. The planning target volume was created by a 5-mm axial and 7-mm (n = 12) or 10-mm (n = 3) craniocaudal expansion of the clinical target volume (CTV) and covered with 67% of the prescribed CTV mean dose. Treatment was gated to the end-exhale phase of the respiratory cycle with beam-on when the target deviated 1 to 2 mm occurred. Log files of transponder motion were used to determine the geometric error and reconstruct the delivered CTV dose in the actual gated treatments and in simulated nongated treatments. No severe side effects were observed in relation to transponder implantation. All 45 treatment fractions were successfully guided using the Calypso system. The mean number of couch corrections during each gated fraction was 2.8 (range 0-7). The mean duty cycle during gated treatment was 62.5% (range 29.1%-84.9%). Without gating, the mean 3-dimensional geometric error during a fraction would have been 5.4 mm (range 2.7-12.1). Gating reduced this error to 2.0 mm (range 1.2-3.0). The patient mean reduction in minimum dose to 95% of the CTV relative to the planned dose was 6.0 percentage points (range 0.7-22.0) without gating and 0.8 percentage point (range 0.2-2.0) with gating. Gating using internal motion monitoring was successfully applied for liver SBRT. It markedly improved the geometric and dosimetric accuracy compared with nongated standard treatment. Copyright © 2018 Elsevier Inc. All rights reserved.

  6. Respiratory gated beam delivery cannot facilitate margin reduction, unless combined with respiratory correlated image guidance

    International Nuclear Information System (INIS)

    Korreman, Stine S.; Juhler-Nottrup, Trine; Boyer, Arthur L.

    2008-01-01

    Purpose/objective: In radiotherapy of targets moving with respiration, beam gating is offered as a means of reducing the target motion. The purpose of this study is to evaluate the safe magnitude of margin reduction for respiratory gated beam delivery. Materials/methods: The study is based on data for 17 lung cancer patients in separate protocols at Rigshospitalet and Stanford Cancer Center. Respiratory curves for external optical markers and implanted fiducials were collected using equipment based on the RPM system (Varian Medical Systems). A total of 861 respiratory curves represented external measurements over 30 fraction treatment courses for 10 patients, and synchronous external/internal measurements in single sessions for seven patients. Variations in respiratory amplitude (simulated coaching) and external/internal phase shifts were simulated by perturbation with realistic values. Variations were described by medians and standard deviations (SDs) of position distributions of the markers. Gating windows (35% duty cycle) were retrospectively applied to the respiratory data for each session, mimicking the use of commercially available gating systems. Medians and SDs of gated data were compared to those of ungated data, to assess potential margin reductions. Results: External respiratory data collected over entire treatment courses showed SDs from 1.6 to 8.1 mm, the major part arising from baseline variations. The gated data had SDs from 1.5 to 7.7 mm, with a mean reduction of 0.3 mm (6%). Gated distributions were more skewed than ungated, and in a few cases a marginal miss of gated respiration would be found even if no margin reduction was applied. Regularization of breathing amplitude to simulate coaching did not alter these results significantly. Simulation of varying phase shifts between internal and external respiratory signals showed that the SDs of gated distributions were the same as for the ungated or smaller, but the median values were markedly shifted

  7. Simulation of time curves in small animal PET using GATE

    International Nuclear Information System (INIS)

    Simon, Luc; Strul, Daniel; Santin, Giovanni; Krieguer, Magalie; Morel, Christian

    2004-01-01

    The ClearPET project of the Crystal Clear Collaboration (CCC) is building spin-off technology for high resolution small animal Positron Emission Tomography (PET). Monte Carlo simulation is essential for optimizing the specifications of these systems with regards to their most important characteristics, such as spatial resolution, sensitivity, or count rate performance. GATE, the Geant4 Application for Tomographic Emission simulates the passing of time during real acquisitions, allowing to handle dynamic systems such as decaying source distributions or moving detectors. GATE output is analyzed on an event-by-event basis. The time associated with each single event allows to sort coincidences and to model dead-time. This leads to the study of time curves for a prospective small animal PET scanner design. The count rates of true, and random coincidences are discussed together with the corresponding Noise Equivalent Count (NEC) rates as a function of some PET scanner specifications such as detector dead time, or coincidence time window

  8. Applying Partial Power-Gating to Direction-Sliced Network-on-Chip

    Directory of Open Access Journals (Sweden)

    Feng Wang

    2015-01-01

    Full Text Available Network-on-Chip (NoC is one of critical communication architectures for future many-core systems. As technology is continually scaling down, on-chip network meets the increasing leakage power crisis. As a leakage power mitigation technique, power-gating can be utilized in on-chip network to solve the crisis. However, the network performance is severely affected by the disconnection in the conventional power-gated NoC. In this paper, we propose a novel partial power-gating approach to improve the performance in the power-gated NoC. The approach mainly involves a direction-slicing scheme, an improved routing algorithm, and a deadlock recovery mechanism. In the synthetic traffic simulation, the proposed design shows favorable power-efficiency at low-load range and achieves better performance than the conventional power-gated one. For the application trace simulation, the design in the mesh/torus network consumes 15.2%/18.9% more power on average, whereas it can averagely obtain 45.0%/28.7% performance improvement compared with the conventional power-gated design. On balance, the proposed design with partial power-gating has a better tradeoff between performance and power-efficiency.

  9. Quantitative Determination on Ionic-Liquid-Gating Control of Interfacial Magnetism.

    Science.gov (United States)

    Zhao, Shishun; Zhou, Ziyao; Peng, Bin; Zhu, Mingmin; Feng, Mengmeng; Yang, Qu; Yan, Yuan; Ren, Wei; Ye, Zuo-Guang; Liu, Yaohua; Liu, Ming

    2017-05-01

    Ionic-liquid gating on a functional thin film with a low voltage has drawn a lot of attention due to rich chemical, electronic, and magnetic phenomena at the interface. Here, a key challenge in quantitative determination of voltage-controlled magnetic anisotropy (VCMA) in Au/[DEME] + [TFSI] - /Co field-effect transistor heterostructures is addressed. The magnetic anisotropy change as response to the gating voltage is precisely detected by in situ electron spin resonance measurements. A reversible change of magnetic anisotropy up to 219 Oe is achieved with a low gating voltage of 1.5 V at room temperature, corresponding to a record high VCMA coefficient of ≈146 Oe V -1 . Two gating effects, the electrostatic doping and electrochemical reaction, are distinguished at various gating voltage regions, as confirmed by X-ray photoelectron spectroscopy and atomic force microscopy experiments. This work shows a unique ionic-liquid-gating system for strong interfacial magnetoelectric coupling with many practical advantages, paving the way toward ion-liquid-gating spintronic/electronic devices. © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  10. Multi-gate Pitot tube for the measurement of water flow in cooling systems; Tubo de Pitot multi-puertos para la medicion de flujo de agua en sistemas de enfriamiento

    Energy Technology Data Exchange (ETDEWEB)

    Figueroa Ibarra, Luis; Rodriguez Martinez, Jose Hugo; Santabarbara Botello, Marcelino [Instituto de Investigaciones Electricas, Cuernavaca, Morelos (Mexico)

    2007-07-01

    In this article the design of a novel measuring device of water flowing in large diameter pipes is described. A description is made of the instrument commonly used at present for this purpose (simple Pitot tube), whose design is based on the Standard CTI Code ATC-105 published by the Cooling Tower Institute (CTI ATC-105, 2000). The disadvantages of the simple Pitot tube in comparison with the new proposed device are emphasized (Multi-gate Pitot tube), of which its construction and design is described in detail. In the present article are also shown the results obtained of the circulation water flow measurements, performed in the cooling system of a fossil fuel power plant. These results are compared with the results of flow measurement obtained by means of the simulation of the thermodynamic cycle of the power station, using commercial software. [Spanish] En este articulo se describe el diseno de un novedoso medidor de flujo de agua que circula en tuberias de gran diametro. Se hace una descripcion del instrumento comunmente usado en la actualidad para dicho proposito (tubo de Pitot simple), cuyo diseno se basa en el estandar CTI Code ATC-105 publicado por el Cooling Tower Institute (CTI ATC-105, 2000). Se puntualizan las desventajas del tubo de Pitot simple en comparacion con el nuevo dispositivo propuesto (tubo de Pitot Multi-puertos), del cual se describe detalladamente su construccion y diseno. En el presente articulo tambien se muestran los resultados obtenidos de las mediciones de flujo de agua de circulacion, realizadas en el sistema de enfriamiento de una central termoelectrica. Dichos resultados son comparados con los resultados de flujo obtenidos mediante simulacion del ciclo termodinamico de la central, usando un software comercial.

  11. Electrical properties of GaAs metal–oxide–semiconductor structure comprising Al2O3 gate oxide and AlN passivation layer fabricated in situ using a metal–organic vapor deposition/atomic layer deposition hybrid system

    Directory of Open Access Journals (Sweden)

    Takeshi Aoki

    2015-08-01

    Full Text Available This paper presents a compressive study on the fabrication and optimization of GaAs metal–oxide–semiconductor (MOS structures comprising a Al2O3 gate oxide, deposited via atomic layer deposition (ALD, with an AlN interfacial passivation layer prepared in situ via metal–organic chemical vapor deposition (MOCVD. The established protocol afforded self-limiting growth of Al2O3 in the atmospheric MOCVD reactor. Consequently, this enabled successive growth of MOCVD-formed AlN and ALD-formed Al2O3 layers on the GaAs substrate. The effects of AlN thickness, post-deposition anneal (PDA conditions, and crystal orientation of the GaAs substrate on the electrical properties of the resulting MOS capacitors were investigated. Thin AlN passivation layers afforded incorporation of optimum amounts of nitrogen, leading to good capacitance–voltage (C–V characteristics with reduced frequency dispersion. In contrast, excessively thick AlN passivation layers degraded the interface, thereby increasing the interfacial density of states (Dit near the midgap and reducing the conduction band offset. To further improve the interface with the thin AlN passivation layers, the PDA conditions were optimized. Using wet nitrogen at 600 °C was effective to reduce Dit to below 2 × 1012 cm−2 eV−1. Using a (111A substrate was also effective in reducing the frequency dispersion of accumulation capacitance, thus suggesting the suppression of traps in GaAs located near the dielectric/GaAs interface. The current findings suggest that using an atmosphere ALD process with in situ AlN passivation using the current MOCVD system could be an efficient solution to improving GaAs MOS interfaces.

  12. Electrical properties of GaAs metal-oxide-semiconductor structure comprising Al2O3 gate oxide and AlN passivation layer fabricated in situ using a metal-organic vapor deposition/atomic layer deposition hybrid system

    Science.gov (United States)

    Aoki, Takeshi; Fukuhara, Noboru; Osada, Takenori; Sazawa, Hiroyuki; Hata, Masahiko; Inoue, Takayuki

    2015-08-01

    This paper presents a compressive study on the fabrication and optimization of GaAs metal-oxide-semiconductor (MOS) structures comprising a Al2O3 gate oxide, deposited via atomic layer deposition (ALD), with an AlN interfacial passivation layer prepared in situ via metal-organic chemical vapor deposition (MOCVD). The established protocol afforded self-limiting growth of Al2O3 in the atmospheric MOCVD reactor. Consequently, this enabled successive growth of MOCVD-formed AlN and ALD-formed Al2O3 layers on the GaAs substrate. The effects of AlN thickness, post-deposition anneal (PDA) conditions, and crystal orientation of the GaAs substrate on the electrical properties of the resulting MOS capacitors were investigated. Thin AlN passivation layers afforded incorporation of optimum amounts of nitrogen, leading to good capacitance-voltage (C-V) characteristics with reduced frequency dispersion. In contrast, excessively thick AlN passivation layers degraded the interface, thereby increasing the interfacial density of states (Dit) near the midgap and reducing the conduction band offset. To further improve the interface with the thin AlN passivation layers, the PDA conditions were optimized. Using wet nitrogen at 600 °C was effective to reduce Dit to below 2 × 1012 cm-2 eV-1. Using a (111)A substrate was also effective in reducing the frequency dispersion of accumulation capacitance, thus suggesting the suppression of traps in GaAs located near the dielectric/GaAs interface. The current findings suggest that using an atmosphere ALD process with in situ AlN passivation using the current MOCVD system could be an efficient solution to improving GaAs MOS interfaces.

  13. Reasons for missed appointments linked to a public-sector intervention targeting patients with stable chronic conditions in South Africa: results from in-depth interviews and a retrospective review of medical records.

    Science.gov (United States)

    Magadzire, Bvudzai P; Mathole, Thubelihle; Ward, Kim

    2017-08-24

    Missed appointments serve as a key indicator for adherence to therapy and as such, identifying patient reasons for this inconsistency could assist in developing programmes to improve health outcomes. In this article, we explore the reasons for missed appointments linked to a centralised dispensing system in South Africa. This system dispenses pre-packed, patient-specific medication parcels for clinically stable patients to health facilities. However, at least 8%-12% of about 300,000 parcels are not collected each month. This article aims to establish whether missed appointments for collection of medicine parcels are indicative of loss-to-follow-up and also to characterise the patient and health system factors linked to missed appointments. We applied an exploratory mixed-methods design in two overlapping research phases. This involved in-depth interviews to yield healthcare practitioners' and patients' experiences and medical record reviews. Data collection was conducted during the period 2014-2015. Qualitative data were analysed through a hybrid process of inductive and deductive thematic analysis which integrated data-driven and theory-driven codes. Data from medical records (N = 89) were analysed in MS excel using both descriptive statistics and textual descriptions. Review of medical records suggests that the majority of patients (67%) who missed original appointments later presented voluntarily to obtain medicines. This could indicate a temporal effect of some barriers. The remaining 33% revealed a range of CDU implementation issues resulting from, among others, erroneous classification of patients as defaulters. Interviews with patients revealed the following reasons for missed appointments: temporary migration, forgetting appointments, work commitments and temporary switch to private care. Most healthcare practitioners confirmed these barriers to collection but perceived that some were beyond the scope of health services. In addition, healthcare

  14. Study of the tunnelling initiated leakage current through the carbon nanotube embedded gate oxide in metal oxide semiconductor structures

    International Nuclear Information System (INIS)

    Chakraborty, Gargi; Sarkar, C K; Lu, X B; Dai, J Y

    2008-01-01

    The tunnelling currents through the gate dielectric partly embedded with semiconducting single-wall carbon nanotubes in a silicon metal-oxide-semiconductor (MOS) structure have been investigated. The application of the gate voltage to such an MOS device results in the band bending at the interface of the partly embedded oxide dielectric and the surface of the silicon, initiating tunnelling through the gate oxide responsible for the gate leakage current whenever the thickness of the oxide is scaled. A model for silicon MOS structures, where carbon nanotubes are confined in a narrow layer embedded in the gate dielectric, is proposed to investigate the direct and the Fowler-Nordheim (FN) tunnelling currents of such systems. The idea of embedding such elements in the gate oxide is to assess the possibility for charge storage for memory device applications. Comparing the FN tunnelling onset voltage between the pure gate oxide and the gate oxide embedded with carbon nanotubes, it is found that the onset voltage decreases with the introduction of the nanotubes. The direct tunnelling current has also been studied at very low gate bias, for the thin oxide MOS structure which plays an important role in scaling down the MOS transistors. The FN tunnelling current has also been studied with varying nanotube diameter

  15. Study of the tunnelling initiated leakage current through the carbon nanotube embedded gate oxide in metal oxide semiconductor structures.

    Science.gov (United States)

    Chakraborty, Gargi; Sarkar, C K; Lu, X B; Dai, J Y

    2008-06-25

    The tunnelling currents through the gate dielectric partly embedded with semiconducting single-wall carbon nanotubes in a silicon metal-oxide-semiconductor (MOS) structure have been investigated. The application of the gate voltage to such an MOS device results in the band bending at the interface of the partly embedded oxide dielectric and the surface of the silicon, initiating tunnelling through the gate oxide responsible for the gate leakage current whenever the thickness of the oxide is scaled. A model for silicon MOS structures, where carbon nanotubes are confined in a narrow layer embedded in the gate dielectric, is proposed to investigate the direct and the Fowler-Nordheim (FN) tunnelling currents of such systems. The idea of embedding such elements in the gate oxide is to assess the possibility for charge storage for memory device applications. Comparing the FN tunnelling onset voltage between the pure gate oxide and the gate oxide embedded with carbon nanotubes, it is found that the onset voltage decreases with the introduction of the nanotubes. The direct tunnelling current has also been studied at very low gate bias, for the thin oxide MOS structure which plays an important role in scaling down the MOS transistors. The FN tunnelling current has also been studied with varying nanotube diameter.

  16. Improvement of breakdown characteristics of an AlGaN/GaN HEMT with a U-type gate foot for millimeter-wave power application

    Science.gov (United States)

    Kong, Xin; Wei, Ke; Liu, Guo-Guo; Liu, Xin-Yu

    2012-12-01

    In this study, the physics-based device simulation tool Silvaco ATLAS is used to characterize the electrical properties of an AlGaN/GaN high electron mobility transistor (HEMT) with a U-type gate foot. The U-gate AlGaN/GaN HEMT mainly features a gradually changed sidewall angle, which effectively mitigates the electric field in the channel, thus obtaining enhanced off-state breakdown characteristics. At the same time, only a small additional gate capacitance and decreased gate resistance ensure excellent RF characteristics for the U-gate device. U-gate AlGaN/GaN HEMTs are feasible through adjusting the etching conditions of an inductively coupled plasma system, without introducing any extra process steps. The simulation results are confirmed by experimental measurements. These features indicate that U-gate AlGaN/GaN HEMTs might be promising candidates for use in millimeter-wave power applications.

  17. The dynamic mechanism of presenilin-function: Sensitive gate dynamics and loop unplugging control protein access

    DEFF Research Database (Denmark)

    Somavarapu, Arun Kumar; Kepp, Kasper Planeta

    2016-01-01

    . Dynamically, these features seem linked. The long-range sensitivity of this gate-plug system to subtle conformational changes can explain why so many PSEN1 mutants cause disease. Reduced access and imprecise substrate cleavage associated with impaired gate-plug dynamics is directly illustrated by the effect......-plug mechanism is relevant for designing PSEN1 modulating therapies for treatment of Alzheimer's disease within both the amyloid/γ-secretase hypothesis and within the PSEN1 loss of function paradigm....

  18. Enhanced antifungal efficacy of tebuconazole using gated pH-driven mesoporous nanoparticles.

    Science.gov (United States)

    Mas, Núria; Galiana, Irene; Hurtado, Silvia; Mondragón, Laura; Bernardos, Andrea; Sancenón, Félix; Marcos, María D; Amorós, Pedro; Abril-Utrillas, Nuria; Martínez-Máñez, Ramón; Murguía, José Ramón

    2014-01-01

    pH-sensitive gated mesoporous silica nanoparticles have been synthesized. Increased extracellular pH and internalization into living yeast cells triggered molecular gate aperture and cargo release. Proper performance of the system was demonstrated with nanodevices loaded with fluorescein or with the antifungal agent tebuconazole. Interestingly, nanodevices loaded with tebuconazole significantly enhanced tebuconazole cytotoxicity. As alterations of acidic external pH are a key parameter in the onset of fungal vaginitis, this nanodevice could improve the treatment for vaginal mycoses.

  19. Calibration of submerged multi-sluice gates

    Directory of Open Access Journals (Sweden)

    Mohamed F. Sauida

    2014-09-01

    The main objective of this work is to study experimentally and verify empirically the different parameters affecting the discharge through submerged multiple sluice gates (i.e., the expansion ratios, gates operational management, etc.. Using multiple regression analysis of the experimental results, a general equation for discharge coefficient is developed. The results show, that the increase in the expansion ratio and the asymmetric operation of gates, give higher values for the discharge coefficient. The obtained predictions of the discharge coefficient using the developed equations are compared to the experimental data. The present developed equations showed good consistency and high accuracy.

  20. A class of quantum gate entanglers

    International Nuclear Information System (INIS)

    Heydari, Hoshang

    2010-01-01

    We construct quantum gate entanglers for different classes of multipartite states based on the definition of W and GHZ concurrence classes. First, we review the basic construction of concurrence classes based on the orthogonal complement of a positive operator valued measure (POVM) on quantum phase. Then, we construct quantum gate entanglers for different classes of multi-qubit states. In particular, we show that these operators can entangle multipartite states if they satisfy some conditions for W and GHZ classes of states. Finally, we explicitly give the W class and GHZ classes of quantum gate entanglers for four-qubit states.

  1. Resonantly driven CNOT gate for electron spins

    Science.gov (United States)

    Zajac, D. M.; Sigillito, A. J.; Russ, M.; Borjans, F.; Taylor, J. M.; Burkard, G.; Petta, J. R.

    2018-01-01

    To build a universal quantum computer—the kind that can handle any computational task you throw at it—an essential early step is to demonstrate the so-called CNOT gate, which acts on two qubits. Zajac et al. built an efficient CNOT gate by using electron spin qubits in silicon quantum dots, an implementation that is especially appealing because of its compatibility with existing semiconductor-based electronics (see the Perspective by Schreiber and Bluhm). To showcase the potential, the authors used the gate to create an entangled quantum state called the Bell state.

  2. Gate A: changes to opening hours

    CERN Multimedia

    2015-01-01

    Due to maintenance work, the opening hours of Gate A (near Reception) will be modified between Monday, 13 and Friday, 17 April 2015.   During this period, the gate will be open to vehicles between 7 a.m. and 9.30 a.m., then between 4.30 p.m. and 7 p.m. It will be completely closed to traffic between 9.30 a.m. and 4.30 p.m. Pedestrians and cyclists may continue to use the gate. We apologise for any inconvenience and thank you for your understanding.

  3. Getting started with FortiGate

    CERN Document Server

    Fabbri, Rosato

    2013-01-01

    This book is a step-by-step tutorial that will teach you everything you need to know about the deployment and management of FortiGate, including high availability, complex routing, various kinds of VPN working, user authentication, security rules and controls on applications, and mail and Internet access.This book is intended for network administrators, security managers, and IT pros. It is a great starting point if you have to administer or configure a FortiGate unit, especially if you have no previous experience. For people that have never managed a FortiGate unit, the book helpfully walks t

  4. UbiGate: a synthetic biology toolbox to analyse ubiquitination.

    Science.gov (United States)

    Kowarschik, Kathrin; Hoehenwarter, Wolfgang; Marillonnet, Sylvestre; Trujillo, Marco

    2018-03-01

    Ubiquitination is mediated by an enzymatic cascade that results in the modification of substrate proteins, redefining their fate. This post-translational modification is involved in most cellular processes, yet its analysis faces manifold obstacles due to its complex and ubiquitous nature. Reconstitution of the ubiquitination cascade in bacterial systems circumvents several of these problems and was shown to faithfully recapitulate the process. Here, we present UbiGate - a synthetic biology toolbox, together with an inducible bacterial expression system - to enable the straightforward reconstitution of the ubiquitination cascades of different organisms in Escherichia coli by 'Golden Gate' cloning. This inclusive toolbox uses a hierarchical modular cloning system to assemble complex DNA molecules encoding the multiple genetic elements of the ubiquitination cascade in a predefined order, to generate polycistronic operons for expression. We demonstrate the efficiency of UbiGate in generating a variety of expression elements to reconstitute autoubiquitination by different E3 ligases and the modification of their substrates, as well as its usefulness for dissecting the process in a time- and cost-effective manner. © 2017 The Authors. New Phytologist © 2017 New Phytologist Trust.

  5. 76 FR 12337 - Request for Applicants for Appointment to the United States-Brazil CEO Forum

    Science.gov (United States)

    2011-03-07

    ... International Trade Administration Request for Applicants for Appointment to the United States- Brazil CEO Forum... 2007, the Governments of the United States and Brazil established the U.S.-Brazil CEO Forum. This... of the Forum. The current U.S. Section term will expire on June 11, 2011. DATES: Applications should...

  6. 78 FR 32239 - Request for Applicants for Appointment to the United States-Brazil CEO Forum

    Science.gov (United States)

    2013-05-29

    ... International Trade Administration Request for Applicants for Appointment to the United States- Brazil CEO Forum... 2007, the Governments of the United States and Brazil established the U.S.-Brazil CEO Forum. This... representatives to the U.S. Section of the Forum. The term of the current representatives to the U.S. Section will...

  7. A Critical Analysis of Judicial Appointment Process and Tenure of Constitutional Justice in Indonesia

    Directory of Open Access Journals (Sweden)

    Pan Mohamad Faiz

    2016-08-01

    Full Text Available The judicial appointment process is one of essential elements for maintaining judicial independence and public confidence of a court. This article analyses the practices of judicial appointment process exercised by three different main state institutions in selecting constitutional justice in Indonesia where the mechanism and process for selecting them have been implemented differently. It also examines the tenure of constitutional justice, which is a five-year term and can be renewed for one term only, that may lead to another problem concerning the reselection process of incumbent constitutional justices for their second term. The article concludes that the judicial appointment process and tenure of constitutional justice in Indonesia have to be improved. It suggests that if the proposing state institutions could not meet the principles of transparency, participation, objective and accountable required by the Constitutional Court Law, the judicial appointment process should be conducted by creating an independent Selection Committee or establishing a cooperation with the Judicial Commission. Additionally, the tenure of constitutional justices should also be revised for a unrenewable term with a longer period of nine or twelve years.

  8. Promotion and Appointment to Administrative Positions of Dental School Faculty by Gender.

    Science.gov (United States)

    Solomon, Eric S.; And Others

    1990-01-01

    A national study examined sex differences in rates of academic promotion and appointment to administrative posts in dental schools since 1985 by looking at promotion rates of faculty who were assistant professors in 1985 and faculty who were associate professors in 1985, and promotions to dean, program director, and department head. (MSE)

  9. 22 CFR 11.5 - Certification for appointment to class 7 or 8.

    Science.gov (United States)

    2010-04-01

    ... duty for required active military service, or required alternative service, civilian Government service... examination in a foreign language, but the appointment will be subject to the condition that the newly..., adequate proficiency in a foreign language is achieved. (22 U.S.C. 1221 et seq.) [37 FR 19356, Sept. 20...

  10. 22 CFR 11.11 - Mid-level Foreign Service officer career candidate appointments.

    Science.gov (United States)

    2010-04-01

    ... Service, and to recommend whether the applicant should be examined for possible appointment under the Mid... professional specialty; knowledge of American history, government, and other features of American culture... Service officer on a world-wide basis and, for candidates and dependents, to determine the presence of any...

  11. 75 FR 65404 - Security Savings Bank, FSB; Olathe, KS; Notice of Appointment of Receiver

    Science.gov (United States)

    2010-10-22

    ... Office of Thrift Supervision Security Savings Bank, FSB; Olathe, KS; Notice of Appointment of Receiver Notice is hereby given that, pursuant to the authority contained in section 5(d)(2) of the Home Owners... Corporation as sole Receiver for Security Savings Bank, FSB, Olathe, Kansas (OTS No. 06084), on October 15...

  12. 77 FR 40341 - Proposed Information Collection; Comment Request; Application for Appointment in the NOAA...

    Science.gov (United States)

    2012-07-09

    ... general public and other Federal agencies to take this opportunity to comment on proposed and/or... Administration (NOAA), a bureau of the Department of Commerce. Officers serve under Senate-confirmed appointments... (extension of a currently approved collection). Affected Public: Individuals or households. Estimated Number...

  13. 75 FR 10789 - Appointments to Performance Review Board for Senior Executive Service

    Science.gov (United States)

    2010-03-09

    ..., Ph.D., Deputy Commissioner, Rehabilitation Services Administration, Department of Education. Abram Claude, Jr., Private Citizen Paul M. Laird, Assistant Director, Industries, Education and Vocational Training and Chief Operating Officer/FPI, Department of Justice. All appointments are made pursuant to...

  14. Use of Six Sigma Methodology to Reduce Appointment Lead-Time in Obstetrics Outpatient Department.

    Science.gov (United States)

    Ortiz Barrios, Miguel A; Felizzola Jiménez, Heriberto

    2016-10-01

    This paper focuses on the issue of longer appointment lead-time in the obstetrics outpatient department of a maternal-child hospital in Colombia. Because of extended appointment lead-time, women with high-risk pregnancy could develop severe complications in their health status and put their babies at risk. This problem was detected through a project selection process explained in this article and to solve it, Six Sigma methodology has been used. First, the process was defined through a SIPOC diagram to identify its input and output variables. Second, six sigma performance indicators were calculated to establish the process baseline. Then, a fishbone diagram was used to determine the possible causes of the problem. These causes were validated with the aid of correlation analysis and other statistical tools. Later, improvement strategies were designed to reduce appointment lead-time in this department. Project results evidenced that average appointment lead-time reduced from 6,89 days to 4,08 days and the deviation standard dropped from 1,57 days to 1,24 days. In this way, the hospital will serve pregnant women faster, which represents a risk reduction of perinatal and maternal mortality.

  15. 48 CFR 1815.207-71 - Appointing non-Government evaluators as special Government employees.

    Science.gov (United States)

    2010-10-01

    ... evaluators as special Government employees. 1815.207-71 Section 1815.207-71 Federal Acquisition Regulations... BY NEGOTIATION Solicitation and Receipt of Proposals and Information 1815.207-71 Appointing non-Government evaluators as special Government employees. (a) Except as provided in paragraph (c) of this...

  16. Predictors of missed research appointments in a randomized placebo-controlled trial

    NARCIS (Netherlands)

    Becker, Stéphanie J. E.; Guitton, Thierry G.; Ring, David

    2014-01-01

    The primary aim of this study was to determine predictors of missed research appointments in a prospective randomized placebo injection-controlled trial with evaluations 1 to 3 and 5 to 8 months after enrollment. This study represents a secondary use of data from 104 patients that were enrolled in a

  17. 19 CFR 141.14 - Deceased or insolvent consignees and court-appointed administrators.

    Science.gov (United States)

    2010-04-01

    ... 19 Customs Duties 2 2010-04-01 2010-04-01 false Deceased or insolvent consignees and court-appointed administrators. 141.14 Section 141.14 Customs Duties U.S. CUSTOMS AND BORDER PROTECTION... administrators. The executor or administrator of the estate of a deceased consignee, the receiver or other legal...

  18. 75 FR 17463 - Key West Bank, Key West, Florida; Notice of Appointment of Receiver

    Science.gov (United States)

    2010-04-06

    ... DEPARTMENT OF THE TREASURY Office of Thrift Supervision Key West Bank, Key West, Florida; Notice of Appointment of Receiver Notice is hereby given that, pursuant to the authority contained in... Federal Deposit Insurance Corporation as sole Receiver for Key West Bank, Key West, Florida, (OTS No...

  19. 76 FR 28130 - Coastal Bank, Cocoa Beach, Florida; Notice of Appointment of Receiver

    Science.gov (United States)

    2011-05-13

    ... DEPARTMENT OF THE TREASURY Office of Thrift Supervision Coastal Bank, Cocoa Beach, Florida; Notice of Appointment of Receiver Notice is hereby given that, pursuant to the authority contained in... Federal Deposit Insurance Corporation as sole Receiver for Coastal Bank, Cocoa Beach, Florida, (OTS No...

  20. 78 FR 59697 - Solicitation for Applications From Individuals Interested in Being Appointed to the Chronic...

    Science.gov (United States)

    2013-09-27

    ... proposed diagnostic and treatment methods for ME/CFS; (3) development and implementation of programs to... makes every effort to ensure that the membership of Federal advisory committees is fairly balanced in... disabilities are given consideration for membership on Federal advisory committees. Appointment to this...