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  1. Ganil results

    International Nuclear Information System (INIS)

    Tamain, B.

    1992-06-01

    Recent Ganil results are presented: hot nuclei properties and multifragmentation, study of flow change around the inversion energy. Mesons and hard photons production are also briefly discussed. Correlations with studies that have been led in Saturne energy range, and the developments that can be foreseen in the future have been discussed

  2. Status report on GANIL

    International Nuclear Information System (INIS)

    Anon.

    1979-01-01

    In August 1975, the French government decided to start the construction at Caen (Normandy) of a national heavy ion facility, Ganil. This program is financed jointly by the I.R.F. (The Institute of Fundamental Research depending of the Atomic Energy Commission) and by the IN 2 P 3 (Institute for Nuclear and Particle Physics depending of the National Center for Scientific Research). Presently 150 persons are working on the Ganil site, mainly machine physicists and technicians

  3. Industrial applications at GANIL

    International Nuclear Information System (INIS)

    Delagrange, H.

    1993-01-01

    After a first round of industrial applications using heavy ion beams, GANIL has refocused these activities along the lines defined by a strategy and market study. Heavy ion industrial applications take their roots in the physical effects of the interactions occurring between heavy ion projectiles and matter. Specific equipments operated by GANIL or CIRIL allow users to take benefit from these effects. By heavy ion irradiation, industrial companies qualify radiation hardened electronic components and sensitize plastic films to produce 'nuclear track' membranes. Research and development programs with laboratories of the public sector, focus on heavy ion lithography dedicated to large area luminescent flat screens with field emitter microtips and on tribology with radioactive implanted ions. Even sometimes facing difficulties to fill the gap between industry and research, GANIL is eager to promote heavy ion beam technologies. (author) 36 refs., 6 figs., 5 tabs

  4. Experimental results obtained at GANIL

    International Nuclear Information System (INIS)

    Borrel, V.

    1993-01-01

    A review of experimental results obtained at GANIL on the study of nuclear structure and nuclear reactions with secondary radioactive beams is presented. Mass measurements by means of the GANIL cyclotrons are described. The possibilities of GANIL/LISE3 for the production and separation of radioactive beams are illustrated through a large variety of experiments. (author). 19 refs., 8 figs

  5. Heavy ion accelerator GANIL

    International Nuclear Information System (INIS)

    1975-04-01

    This article presents GANIL, a large national heavy ion accelerator. The broad problems of nuclear physics, atomic physics, astrophysics and physics of condensed media which can be approached and studied with this machine are discussed first, after which the final construction project is described. The project comprises a circular injector, a separated sector cyclotron up beam stripper, and a second separated cyclotron downstream [fr

  6. Colloquium GANIL 2006; Colloque GANIL 2006

    Energy Technology Data Exchange (ETDEWEB)

    Hammache, F.; D' Auria, J.; Sereville, N. de; Kratz, K.L.; Horowitz, C.J.; Grasso, M.; Sebille, F.; Stefan, I.; Yeremin, A.; Villari, A.C.C.; Drouart, A.; Schmitt, Ch.; Jurado, B.; Lopez, O.; Poggi, G.; Frankland, J.; Ducoin, C.; Beaumel, D.; Keeley, N.; Gelin, M.; Caamano, M.; Monrozeau, C.; Catford, W.; Simpson, G.; Scarpaci, J.A.; Dudek, J.; Nguyen, V.G.; Bender, M.; Sida, J.L.; Azaiez, F.; Duchene, G.; Beuve, M.; Burger, A.; Matea, I.; Gaubert, G.; Gorgen, A.; Sletten, G.; Courtin, S.; Petrache, C.; Ma, A.; Motobayashi, T.; Riisager, K.; Lukic, S.; Thomas, J.C.; Langanke, K.; Nilsson, T.; Neyens, G.; Georgiev, G.; Daugas, J.M.; Mueller, P.; Herlert, A.; Delahaye, P.; Borge, M.J.G.; Severijns, N.; Mery, A.; Plompen, A.; Fisher, U.; Lewitowicz, M.; Acosta, L.; Ban, S.; Boutin, D.; Daugas, J.M.; Dossat, C.; Iwata, Y.; Kumar, V.; Maslov, V.; Paschalis, S.; Petri, M.; Wrzosek, K.; Kumar, V

    2006-07-01

    The purpose of this conference was to review and discuss the research carried out at GANIL and the related activities at similar facilities around the world. The experiments performed in the first 4 years of operation of the Spiral facility as well as its future developments were largely discussed. Several sessions of the workshop were also devoted to the presentation and the discussion of the future physics opportunities with Spiral-2 and needed technical developments. The presentations have been organized into 13 topics: 1) nuclear astrophysics, 2) heavy and super-heavy nuclei, 3) multifragmentation, 4) structure and spectroscopy, 5) nuclear structure theories, 6) towards the drip-lines, 7) interdisciplinary sciences, 8) neutron-deficient nuclei, 9) gamma spectroscopy, 10) worldwide physics, 11) nuclear moments, 12) DESIR, and 13) nuclear data. This document gathers the slides of the presentations as well as the posters of the poster session.

  7. Secondary beams at GANIL

    International Nuclear Information System (INIS)

    Doubre, H.

    1992-01-01

    GANIL, a user's facility since 1983, can deliver a broad spectrum of heavy-ion beams, from He to U, to well-equipped experimental areas. Their very large intensities are to be exploited to produce secondary beams, either using the fragmentation method (beams at energy per nucleon larger than 30 MeV/u), or the ISOL method. With the latter one, these ions have to be re-accelerated. The project of a cyclotron as a post-accelerator is described. (author) 11 refs.; 7 figs.; 3 tabs

  8. Sissi at Ganil

    International Nuclear Information System (INIS)

    Anne, R.

    1996-01-01

    In the continuation of secondary beams production studies started in the eighties, GANIL laboratory has been running for two years an efficient device called SISSI, dedicated to the production of exotic beams by projectile fragmentation. It is based on two superconducting solenoids surrounding a thick target. Its magnetic field is as high as 11 T and its nominal angular acceptance around 160 mr. SISSI is located at the CSS2 cyclotron exit that is upstream the selecting alpha spectrometer nd all the experiments rooms which can therefore receive secondary beams on any target. (author). 11 refs., 9 figs., 1 tab

  9. GANIL beam profile detectors

    International Nuclear Information System (INIS)

    Tribouillard, C.

    1997-01-01

    In the design phase of GANIL which started in 1977, one of the priorities of the project management was equipping the beamlines with a fast and efficient system for visualizing the beam position, thus making possible adjustment of the beam transport lines optics and facilitating beam control. The implantation of some thirty detectors was foreseen in the initial design. The assembly of installed detectors (around 190) proves the advantages of these detectors for displaying all the beams extracted from GANIL: transfer and transport lines, beam extracted from SISSI, very high intensity beam, secondary ion beams from the production target of the LISE and SPEG spectrometers, different SPIRAL project lines. All of these detectors are based on standard characteristics: - standard flange diameter (DN 160) with a standard booster for all the sensors; - identical analog electronics for all the detectors, with networking; - unique display system. The new micro-channel plate non-interceptive detectors (beam profile and ion packet lengths) make possible in-line control of the beam quality and accelerator stability. (author)

  10. Colloquium GANIL 2006

    International Nuclear Information System (INIS)

    Hammache, F.; D'Auria, J.; Sereville, N. de; Kratz, K.L.; Horowitz, C.J.; Grasso, M.; Sebille, F.; Stefan, I.; Yeremin, A.; Villari, A.C.C.; Drouart, A.; Schmitt, Ch.; Jurado, B.; Lopez, O.; Poggi, G.; Frankland, J.; Ducoin, C.; Beaumel, D.; Keeley, N.; Gelin, M.; Caamano, M.; Monrozeau, C.; Catford, W.; Simpson, G.; Scarpaci, J.A.; Dudek, J.; Nguyen, V.G.; Bender, M.; Sida, J.L.; Azaiez, F.; Duchene, G.; Beuve, M.; Burger, A.; Matea, I.; Gaubert, G.; Gorgen, A.; Sletten, G.; Courtin, S.; Petrache, C.; Ma, A.; Motobayashi, T.; Riisager, K.; Lukic, S.; Thomas, J.C.; Langanke, K.; Nilsson, T.; Neyens, G.; Georgiev, G.; Daugas, J.M.; Mueller, P.; Herlert, A.; Delahaye, P.; Borge, M.J.G.; Severijns, N.; Mery, A.; Plompen, A.; Fisher, U.; Lewitowicz, M.; Acosta, L.; Ban, S.; Boutin, D.; Daugas, J.M.; Dossat, C.; Iwata, Y.; Kumar, V.; Maslov, V.; Paschalis, S.; Petri, M.; Wrzosek, K.; Kumar, V.

    2006-01-01

    The purpose of this conference was to review and discuss the research carried out at GANIL and the related activities at similar facilities around the world. The experiments performed in the first 4 years of operation of the Spiral facility as well as its future developments were largely discussed. Several sessions of the workshop were also devoted to the presentation and the discussion of the future physics opportunities with Spiral-2 and needed technical developments. The presentations have been organized into 13 topics: 1) nuclear astrophysics, 2) heavy and super-heavy nuclei, 3) multifragmentation, 4) structure and spectroscopy, 5) nuclear structure theories, 6) towards the drip-lines, 7) interdisciplinary sciences, 8) neutron-deficient nuclei, 9) gamma spectroscopy, 10) worldwide physics, 11) nuclear moments, 12) DESIR, and 13) nuclear data. This document gathers the slides of the presentations as well as the posters of the poster session

  11. The Lise spectrometer at Ganil

    International Nuclear Information System (INIS)

    Saint-Laurent, M.G.

    1986-08-01

    The doubly achromatic spectrometer LISE is available at the french national heavy ion accelerator GANIL. Experimental results, obtained in radioactive beam production and search for new exotic nuclei are briefly reported

  12. GANIL Workshop on Ion Sources

    International Nuclear Information System (INIS)

    Leroy, Renan

    1999-01-01

    The proceedings of the GANIL Workshop on Ion Sources held at GANIL - Caen on 18-19 March 1999 contains 13 papers aiming at improving the old source operation and developing new types of sources for nuclear research and studies of ion physics. A number of reports are devoted to applications like surface treatment, ion implantation or fusion injection. The 1+→n+ transformation, charged particle transport in ECR sources, addition of cesium and xenon in negative ion sources and other basic issues in ion sources are also addressed

  13. 4π detector at GANIL

    International Nuclear Information System (INIS)

    Babinet, R.; Cassagnou, Y.; Girard, J.

    1979-01-01

    The preliminary ideas put forward by a group of physicists on a wide geometry (approximately 4π) detector for the multiple detection of light particles at Ganil are summarized. The Diogene project of Saturne II served as a basis for the ideas developed [fr

  14. A review on SHE research at GANIL

    International Nuclear Information System (INIS)

    Stodel, Ch.; Anne, R.; Bouriquet, B.; Cee, R.; France, G. de; Oliveira Santos, F. de; Tourreil, R. de; Grevy, S.; Peghaire, A.; Saint-Laurent, M.-G.; Villari, A. C. C.; Wieleczko, J.-P.; Amar, N.; Peter, J.; Auger, G.; Casandjian, J.-M.; Clement, E.; Dayras, R.; Drouart, A.; Theisen, Ch.

    2007-01-01

    This report summarizes the experiments relative to Super-Heavy Element studies done at GANIL - CEA - CNRS since 1999. It also gives an overview of future experiments and opportunities offered by SPIRAL 2 and LINAG beams in a medium term.

  15. The GANIL plus program for a RNB facility at GANIL

    International Nuclear Information System (INIS)

    Anne, R.; Bertrand, P.; Bourgarel, M.P.; Bieth, C.; Obert, J.; Putaux, J.C.; Liang, C.F.; Paris, P.; Orr, N.; Steckmayer, J.C.

    1993-01-01

    At first version of isotopic separator on-line test bench has been built in order to test the feasibility of the production of radioactive species from 96 MeV/u of 20 Ne impinging a thick target of MgO. This test bench was equipped with a very compact ECR ion source (Nanogan) entirely made from permanent magnets and operating at 10 Ghz. 18 Ne 2,4+ ; 19 Ne 1,2,3,4+ and 23,24 Ne 1+ have been produced and ionized. A new more performing separator (SIRa) allowing the use of different ion sources will be completed by the end of 1993. This separator is one stage of the project of a RNB facility called GANIL PLUS. This facility can be decomposed into two parts: The THI project and the SPIRaL project which includes the production, the separation and the acceleration of radioactive ions. These projects are presented here. (author) 3 refs., 3 figs., 1 tab

  16. Power supply control protocol used at GANIL

    International Nuclear Information System (INIS)

    Prome, M.; Baumgarten, R.; Luong, T.T.

    1986-01-01

    This document intends to establish specifications for power supply control so that, if complied with by power supply manufacturers, power supplies from any manufacturer can be linked at once to the Ganil Control system. The only points to take care of are reduced to physical link and filling of the data base

  17. New developments of the GANIL control system

    International Nuclear Information System (INIS)

    Lecorche, E.

    1985-10-01

    Since its first ion beam, the GANIL accelerator has been driven by a Control System built around a minicomputer MITRA 125 and a distributed intelligence consisting of programmable Controllers and INTEL 8080 equipped autonomous CAMAC Controllers. After a brief description of the GANIL Control System, this paper will lay emphasis on the major improvements undertaken along four main directions: a) Upgrading the Control Computer. b) Introducing more powerful local intelligence. A microprocessorized autonomous CAMAC Controller called ''DIVA 68C'' using the 68000 microprocessor embedded in a VME card has been developed. Also, the 68000 will be used in a general purpose CAMAC module, the first application of which is to replace the existing data link modules. (c) Making human-machine dialog smarter with use of color graphic terminals. d) Meeting the requirements of the coming second injector. In this purpose a fully equipped auxiliary console is being installed near the main console for operation by summer 1985

  18. 3. Ganil session, 19 - 21 November 1979

    International Nuclear Information System (INIS)

    1979-11-01

    This report on the GANIL meetings held at CAEN the 19th, 20th and 21st of November 1979 treats first of all the opening presentation on the state of advancement of the project and the most recent principal characteristics of the beams. The texts of the sixteen adjoining papers cover an important stage in the evolution between the discussions of the 1977 meetings and the beam that we hope will be available at the end of 1982 [fr

  19. New developments of the GANIL control system

    International Nuclear Information System (INIS)

    Lecorche, E.

    1986-01-01

    Since the first ion beam, the GANIL accelerator has been driven by a Control System built around a minicomputer MITRA 125 and a distributed intelligence consisting of Programmable Controllers and INTEL 8080-equipped autonomous CAMAC Controllers. CAMAC is the digital transmission standard adopted to interface the processors to the GANIL facilities. In order to cope with the growing needs of the accelerator operation, many developments of the Control System have been carried out during the last years or are underway. After a brief description of the GANIL Control System, this paper describes the major improvements undertaken in four main directions: a) Upgrading the Control Computer. The minicomputer MITRA 125 will be replaced by a faster one equipped with much larger memories and disk capabilities. b) Introducing more powerful local intelligence. An autonomous CAMAC Controller called DIVA 68C using the 68000 microprocessor has been developed. Also, the 68000 will be used in a general purpose CAMAC module, the first application of which is to replace the existing data link modules. c) Improving the human-machine interface with the use of color graphic terminals. d) Meeting the requirements for the coming second injector. For this purpose, a fully equipped auxiliary console is being installed near the main console for operation by summer 1985. (orig.)

  20. The operation of the GANIL control system

    International Nuclear Information System (INIS)

    Prome, M.; David, L.; Lecorche, E.

    1984-06-01

    When the first GANIL beams were obtained the control system was operating in an elementary way; the system behaved almost like a huge multiplexer. Now a large number of programs have been written; they allow to take benefit of the full power of the computers; they help the operators for starting, tuning and monitoring the accelerator. The paper gives a general description of these programs which are executed on the central computer: it shows how the accelerator is controlled either directly or via dedicated microprocessors. Informations are also given on the alarm system

  1. The next generation control system of GANIL

    International Nuclear Information System (INIS)

    Luong, T.T.; David, L.; Lecorche, E.; Ulrich, M.

    1992-01-01

    A short description of the new control system of GANIL is presented. It consists of a three layer distributed architecture of a VAX6000-410/VMS host computer, a real time control system made up of a dual-host VAX3800 and workstation based operator consoles, and VME and CAMAC processors at the frontend segment, running under the VAXELN operating system, and programmable logic controllers for local controls. The basic issues with regard to architecture, human interface, information management, etc. are discussed. First implementations and operation results are presented. (author) 11 figs

  2. Upgrade of GANIL control system cluster

    International Nuclear Information System (INIS)

    David, L.

    1998-01-01

    The GANIL control system was based on VAX 32 bit computers connected on a coaxial ethernet network. Since last year we are using an Alpha server with 64 bit Alpha workstations. At the same time the network is moving to twisted pair linked to a HUB concentrator, which is itself connected to the main FDDI ring. Solutions to solve the following problems are presented: the generalization of control graphical interfaces; extensive usage of the data base; the compilation of the more complex units; object programming; adaption to the new materials technologies; migration towards another operating system. Also described is the modification in the network imposed by the supplementary control of SPIRAL

  3. Present and future development at Ganil

    International Nuclear Information System (INIS)

    Ferme, J.

    1988-01-01

    GANIL has been in operation since January 1983. During this period beams from Carbon to Xenon have been available continuously for physics. There is now a demand to extend the ion range up to uranium, and to increase the beam intensity above the present level of about 3 microamperes with light ions. The corresponding modifications of the machine have been studied and will be made in the near future. Progress in ion sources, beam diagnostics, computer control is reported. Speculative considerations on the distant future are discussed

  4. Extending the GANIL control system for the SPIRAL project

    International Nuclear Information System (INIS)

    Lecorche, E.

    1997-01-01

    The SPIRAL project under construction at GANIL aims to deliver radioactive ion beams to the physicists by the end of 1998. In 1996, it has been proposed to achieve most of the SPIRAL control system as an extension of the system currently in use at GANIL. Therefore the main features of the GANIL control system design are first recalled. Then the paper shows how the GANIL control system should have been upgraded and extended to integrate the SPIRAL project. This evolution had to cope with the specific needs brought by the new machine and to consider the size of the project which is around one third of the GANIL control system volume. Lastly current status of the system is given. (author)

  5. Extending the GANIL control system for the SPIRAL project

    Energy Technology Data Exchange (ETDEWEB)

    Lecorche, E

    1997-12-31

    The SPIRAL project under construction at GANIL aims to deliver radioactive ion beams to the physicists by the end of 1998. In 1996, it has been proposed to achieve most of the SPIRAL control system as an extension of the system currently in use at GANIL. Therefore the main features of the GANIL control system design are first recalled. Then the paper shows how the GANIL control system should have been upgraded and extended to integrate the SPIRAL project. This evolution had to cope with the specific needs brought by the new machine and to consider the size of the project which is around one third of the GANIL control system volume. Lastly current status of the system is given. (author) 5 refs.

  6. Status of SPIRAL. The radioactive beam project at GANIL

    International Nuclear Information System (INIS)

    Lieuvin, M.

    1995-01-01

    SPIRAL, a radioactive ion beam facility (RIB) is under construction at GANIL (Caen, France). The heavy ion beams of GANIL will be used to produce radioactive atoms by the ISOL method. After ionisation by an ECR ion source (ECRIS), the low energy radioactive beam is axially injected on the first orbit of a k=265 compact cyclotron. The final energy will range between 1.7 and 25 MeV/u (harmonics 5 to 2) and the accelerated ions will be sent to the existing GANIL experimental areas. The present status of the project is described. (author)

  7. The new accelerator control system of GANIL

    International Nuclear Information System (INIS)

    Luong, T.T.; David, L.; Duneau, P.; De Saint Jores, P.; Lecorche, E.; Lemaitre, E.; Lermine, P.; Loyant, J.M.; Maugeais, C.; Regnault, F.; Roze, J.F.; Souf, A.; Ulrich, M.

    1994-01-01

    The new computer control system has operated the heavy ion accelerator GANIL from the beginning of 1993 and has reached a state of routine operation. It supersedes the obsolete initial system to cope with the harsh experimental conditions required by the very high intensity beams expected in the near future. Hardware and software implementations, as well as the human interface, are presented. Emphasis is placed on the three-layer distributed architecture adopted. An Ethernet local area network (LAN) links the basic components: a VAX/VMS cluster, XWINDOWS-interfaced operator consoles, VAXELN-driven CAMAC crate controllers and programmable logic controllers for the front end controls. Also the data management, through the INGRES relational database management system (RDBMS), as well as the operating software written in ADA, are described. The early experience with the new control system is reported and future developments discussed. ((orig.))

  8. The Ganil computer control system renewal

    International Nuclear Information System (INIS)

    David, L.; Lecorche, E.; Luong, T.T.; Ulrich, M.

    1990-01-01

    Since 1982 the GANIL heavy ion accelerator has been under the control of 16-bit minicomputers MITRA, programmable logic controllers and microprocessorized Camac controllers, structured into a partially centralized system. This control system has to be renewed to meet the increasing demands of the accelerator operation which aims to provide higher quality ion beams under more reliable conditions. This paper gives a brief description of the existing control system and then discusses the main issues of the design and the implementation of the future control system: distributed powerful processors federated through Ethernet and flexible network-wide database access, VME standard and front-end microprocessors, enhanced color graphic tools and workstation based operator interface

  9. Status of the LPCTrap facility at GANIL

    International Nuclear Information System (INIS)

    Duval, F.; Mery, A.; Ban, G.; Durand, D.; Flechard, X.; Labalme, M.; Lienard, E.; Mauger, F.; Naviliat-Cuncic, O.; Rodriguez-Rubiales, D.; Thomas, J.C.

    2008-01-01

    The LPCTrap is a device whose central element is a transparent Paul trap for the efficient trapping of low energy radioactive ions produced by the SPIRAL facility at GANIL. The installation comprises a linear RFQ cooler and buncher for the beam preparation, and a decay chamber where the Paul trap is located. The system has been tested with ions having mass-to-charge ratios ranging from 4 to 40. The first run with radioactive 6 He + ions has demonstrated the overall performance of the system. In this contribution we describe the current status of the device, we present in particular the results of a numerical study carried out to determine the properties of the ion cloud inside the trap and provide updated values for the overall efficiency of the system.

  10. Research at GANIL 1998/2000

    International Nuclear Information System (INIS)

    Frankland, J.; Rothard, H.; Bex, M.

    2002-01-01

    The present compilation, which gathers 72 articles, tends to reflect a variety of experimental and theoretical works performed at GANIL in the years 1998-2000. This ''just-before-SPIRAL'' period was characterized in nuclear physics by a strong increase in the number of experiments dedicated to the study of the structure of nuclei far from stability. The identification of the doubly-magic 48 Ni and study of the neighbouring nuclei are among the most spectacular results of this research. The contributions have been parted into the following topics: 1) nuclear theory, 2) exotic nuclei: reactions, 3) exotic nuclei: spectroscopy, 4) hot nuclei and hot matter, 5) instrumentation, 6) collisions of ions with atoms and molecules, 7) collisions with solids and surfaces, transport phenomena, energy deposition and sputtering, 8) induced effects in condensed matter including nano-structuration, and 9) radiation chemistry and radiobiology. (A.C.)

  11. Precision measurements with LPCTrap at GANIL

    Energy Technology Data Exchange (ETDEWEB)

    Liénard, E., E-mail: lienard@lpccaen.in2p3.fr; Ban, G. [LPC CAEN, ENSICAEN, Université de Caen, CNRS/IN2P3 (France); Couratin, C. [Instituut voor Kern- en Stralingsfysica, KU Leuven (Belgium); Delahaye, P. [GANIL, CEA/DSM-CNRS/IN2P3 (France); Durand, D.; Fabian, X. [LPC CAEN, ENSICAEN, Université de Caen, CNRS/IN2P3 (France); Fabre, B. [CELIA, Université Bordeaux, CNRS, CEA (France); Fléchard, X. [LPC CAEN, ENSICAEN, Université de Caen, CNRS/IN2P3 (France); Finlay, P. [Instituut voor Kern- en Stralingsfysica, KU Leuven (Belgium); Mauger, F. [LPC CAEN, ENSICAEN, Université de Caen, CNRS/IN2P3 (France); Méry, A. [CIMAP, CEA/CNRS/ENSICAEN, Université de Caen (France); Naviliat-Cuncic, O. [NSCL and Department of Physics and Astronomy, MSU (United States); Pons, B. [CELIA, Université Bordeaux, CNRS, CEA (France); Porobic, T. [Instituut voor Kern- en Stralingsfysica, KU Leuven (Belgium); Quéméner, G. [LPC CAEN, ENSICAEN, Université de Caen, CNRS/IN2P3 (France); Severijns, N. [Instituut voor Kern- en Stralingsfysica, KU Leuven (Belgium); Thomas, J. C. [GANIL, CEA/DSM-CNRS/IN2P3 (France); Velten, Ph. [Instituut voor Kern- en Stralingsfysica, KU Leuven (Belgium)

    2015-11-15

    The experimental achievements and the results obtained so far with the LPCTrap device installed at GANIL are presented. The apparatus is dedicated to the study of the weak interaction at low energy by means of precise measurements of the β − ν angular correlation parameter in nuclear β decays. So far, the data collected with three isotopes have enabled to determine, for the first time, the charge state distributions of the recoiling ions, induced by shakeoff process. The analysis is presently refined to deduce the correlation parameters, with the potential of improving both the constraint deduced at low energy on exotic tensor currents ({sup 6}He{sup 1+}) and the precision on the V{sub ud} element of the quark-mixing matrix ({sup 35}Ar{sup 1+} and {sup 19}Ne{sup 1+}) deduced from the mirror transitions dataset.

  12. Status report on the GANIL renovation program

    International Nuclear Information System (INIS)

    Loyer, F.

    1995-01-01

    Three years ago, a renovation program was initiated to ensure GANIL a lifetime of at least 15 years in order to allow an efficient use of the two radioactive ion beam facilities, SISSI which has been operational since last year and SPIRAL which will be in use in 98. The status of this program is reported which mainly concerns the control system, the RF systems (voltage and phase control devices), the vacuum system (control and pumping devices), the power supplies (interfaces, current sensors, and internal electronics), the beam instrumentation (electronics and local control devices) and the system which survey the accelerator access. The improvements of the accelerator ECR sources are also described and the first results to produce refractor metallic ion beams like uranium are mentioned. (author)

  13. The next generation control system of GANIL

    International Nuclear Information System (INIS)

    Luong, T.T.; David, L.; Lecorche, E.; Ulrich, M.

    1992-01-01

    The existing computer control system of GANIL is being renewed to fulfil the increasing requirements of the accelerator operation. This medium term major improvement is aiming at providing the physicists with a wider range of ion beams of higher quality under more flexible and reliable conditions. This paper gives a short description of the new control system envisioned. It consists of a three layer distributed architecture federating a VAX6000-410/VMS host computer, a real time control system made up of a dual host VAX3800 and workstation based operator consoles, and at the frontend segment: VME and CAMAC processors running under the VAXELN operating system, and programmable logic controllers for local controls. The basic issues with regard to architecture, human interface, information management, ... are discussed. Lastly, first implementations and operation results are presented. (author)

  14. Research at GANIL 1998/2000

    Energy Technology Data Exchange (ETDEWEB)

    Frankland, J.; Rothard, H.; Bex, M. (eds.)

    2002-01-01

    The present compilation, which gathers 72 articles, tends to reflect a variety of experimental and theoretical works performed at GANIL in the years 1998-2000. This ''just-before-SPIRAL'' period was characterized in nuclear physics by a strong increase in the number of experiments dedicated to the study of the structure of nuclei far from stability. The identification of the doubly-magic {sup 48}Ni and study of the neighbouring nuclei are among the most spectacular results of this research. The contributions have been parted into the following topics: 1) nuclear theory, 2) exotic nuclei: reactions, 3) exotic nuclei: spectroscopy, 4) hot nuclei and hot matter, 5) instrumentation, 6) collisions of ions with atoms and molecules, 7) collisions with solids and surfaces, transport phenomena, energy deposition and sputtering, 8) induced effects in condensed matter including nano-structuration, and 9) radiation chemistry and radiobiology. (A.C.)

  15. The new accelerator control system of GANIL

    International Nuclear Information System (INIS)

    Luong, T.T.; David, L.; Duneau, P.; Saint Jores, P. De; Lecorche, E.; Lemaitre, E.; Lermine, P.; Loyant, J.M.; Maugeais, C.; Regnault, F.

    1993-01-01

    The new computer control system is conducting the heavy ion accelerator GANIL from the beginning of 1993 and has reached a state of routine operation. It was carried out to supersede the obsolete initial system and to cope with the harsh experimental conditions required by the very high intensity beams envisioned for the next future. Hardware and software implementations, as well as human interface, are presented. Emphasis is placed on the three-layer distributed architecture adopted. An ETHERNET local area network (LAN) links the basic components: a VAX/VMS cluster, XWINDOWS interfaced operator consoles, VAXELN driven CAMAC crate controllers and programmable logic controllers for front end controls. Also data management with the INGRES relational database management system (RDBMS), as well as operating software written in ADA language, are described. First experience with the new control system is reported. Finally, trend considerations are addressed. (author) 8 refs., 6 figs

  16. Vanglateenistuse enesekaitsekoolitus / Henri Palm

    Index Scriptorium Estoniae

    Palm, Henri

    2014-01-01

    Vanglateenistus korraldab Tartus, Tallinnas ja Jõhvis enesekaitsekoolitusi gümnaasiumiõpilastele. Jakob Westholmi abiturient Henri Palm on osalenud treeningutel osalenud kolm aastat ning jagab kogemusi

  17. Interview with Henry Jenkins

    OpenAIRE

    TWC Editor

    2008-01-01

    An interview with Henry Jenkins focussing on Transformative Works and Cultures (TWC), the Organization for Transformative Works (OTW), and Jenkins' academic research into fan and participatory cultures.

  18. Nuclear physics at GANIL. A compilation 1994-1995

    International Nuclear Information System (INIS)

    Bex, M.; Galin, J.

    1996-09-01

    Different aspects of heavy ion reactions have been investigated at GANIL. Recent results on nuclear fragmentation and nuclear reaction kinetics are presented. 67 items are indexed and abstracted separately for INIS database. (K.A.)

  19. Nuclear physics at GANIL. A compilation 1994-1995

    Energy Technology Data Exchange (ETDEWEB)

    Bex, M; Galin, J [eds.

    1996-09-01

    Different aspects of heavy ion reactions have been investigated at GANIL. Recent results on nuclear fragmentation and nuclear reaction kinetics are presented. 67 items are indexed and abstracted separately for INIS database. (K.A.).

  20. Nuclear physics at Ganil; a compilation january 1983 december 1988

    International Nuclear Information System (INIS)

    1989-01-01

    The results of some of the experiments carried out at GANIL from 1983 to 1988 are summarized. Theoretical and experimental work on the following fields are presented: nuclear structure, reaction mechanisms, hot nuclear matter, production and properties of exotic nuclei, collective motions in nuclei, peripheral collisions, multi-fragment emission, pions and photons and technical developments. A list of the papers from the experiments carried out at GANIL, together with scientific activities are given

  1. Interview with Henry Jenkins

    Directory of Open Access Journals (Sweden)

    TWC Editor

    2008-09-01

    Full Text Available An interview with Henry Jenkins focussing on Transformative Works and Cultures (TWC, the Organization for Transformative Works (OTW, and Jenkins' academic research into fan and participatory cultures.

  2. Henry Ford Health Systems

    Science.gov (United States)

    Henry Ford Health Systems evolved from a hospital into a system delivering care to 2.5 million patients and includes the Cancer Epidemiology, Prevention and Control Program, which focuses on epidemiologic and public health aspects of cancer.

  3. GANIL, Technical report on operating accelerators, 1995-1996

    International Nuclear Information System (INIS)

    Bex, M.

    1998-01-01

    This report covers the years 1995-1996 and presents the GANIL accelerator operation, the machine studies, the technical developments, the safety problems, the SISSI system and the THI project. The technical developments refer to: production of multicharged metallic ions by the association of an excimer laser and an ECR source; production of multicharged metallic ions with an ECR source by the sputtering method; detection of beam losses and safety system for these losses; rotating spiraled wire; renovation or RF systems; renovation of power supplies and NMR system; upgrade of GANIL control system cluster; adaptation of the GANIL control system to the SPIRAL project and control system for NMR probe measurements. Annexes giving the experiments performed in nuclear physics and in fast ion physics are given as well as a list of the beams accelerated together with their characteristics (charged state, frequency, final energy, intensity on target). Also added is a list of publications

  4. Software trends for both the GANIL and spiral control

    International Nuclear Information System (INIS)

    David, L.; Lecorche, E.

    1999-01-01

    The Ganil facility has been running with a new control system since 1993. Many improvements have been done since that time to bring new capabilities to the system. So, in February 1996, when the Spiral control system was designed, it was mainly considered as an extension of the Ganil control system. This paper briefly recalls the basic architecture of the whole control system and the main choices upon which it relies. Then it presents the new software trends, to show how the Spiral control system has been integrated alongside the existing one. The last part describe the new developments and the most significant functionalities it brings as seen from the operator point of view, with some emphasis about the application programs for beam tuning. Indeed, these new programs have to be provided both for the spiral tuning with exotic ions beams and for the coupling of the Spiral and older Ganil facilities. (authors)

  5. Industrial applications of heavy ions beams at GANIL

    International Nuclear Information System (INIS)

    Bieth, C.; Van Den Bossche, M.; Busardo, D.; Balanzat, E.; Meslage, J.; Pierrard, P.

    1988-01-01

    After a year of research and development, BSI and GANIL started an industrial production of microporous membranes. The status of the technical and commercial problems is given. With the collaboration of indutrial firms, other applications are studied, like: non reflecting surfaces, ion implantation, surface treatment, radiation damage

  6. Henry Gray's Anatomy.

    Science.gov (United States)

    Pearce, J M S

    2009-04-01

    Little is generally known of Henry Gray, the author of Gray's Anatomy, and even less of his colleague Henry Vandyke Carter, who played a vital role in the dissections and illustrations leading to the production of the first volume in 1859. This essay attempts to sketch briefly the salient, know aspects of these two men and their divergent careers. It traces succinctly the subsequent fate of the unique anatomy book that has influenced and instructed almost every student of medicine. (c) 2009 Wiley-Liss, Inc.

  7. Database management in the new GANIL control system

    International Nuclear Information System (INIS)

    Lecorche, E.; Lermine, P.

    1993-01-01

    At the start of the new control system design, decision was made to manage the huge amount of data by means of a database management system. The first implementations built on the INGRES relational database are described. Real time and data management domains are shown, and problems induced by Ada/SQL interfacing are briefly discussed. Database management concerns the whole hardware and software configuration for the GANIL pieces of equipment and the alarm system either for the alarm configuration or for the alarm logs. An other field of application encompasses the beam parameter archiving as a function of the various kinds of beams accelerated at GANIL (ion species, energies, charge states). (author) 3 refs., 4 figs

  8. HENRY'S "HAND OF GOD"

    Directory of Open Access Journals (Sweden)

    Željko Kaluđerović

    2014-04-01

    Full Text Available In this paper the author discusses the views and statements of the French football player Thierry Henry he gave after his illegal play during the playoff match between France and the Republic of Ireland to claim one of the final spots in the World Cup 2010 in South Africa. First, by controlling the ball with his hand before passing it on for the goal Henry has shown disregard for the constitutive rules of football. Then, by stating that he is "not a referee" he demonstrated that for some players rules are not inherent to football and that they can be relativized, given that for them winning is the goal of the highest ontological status. Furthermore, he has rejected the rules of sportsmanship, thus expressing his opinion that the opponents are just obstacles which have to be removed in order to achieve your goals. Henry's action has disrupted major moral values, such as justice, honesty, responsibility and beneficence. The rules of fair play have totally been ignored both in Henry's action and in the Football Association of France's unwillingness to comment on whether a replay should take place. They have ignored one of the basic principles stated in the "Declaration of the International Fair Play Committee", according to which, fair play is much more than playing to the rules of the game; it's about the attitude of the sportsperson. It's about respecting your opponent and preserving his or her physical and psychological integrity. Finally, the author believes that the rules, moral values and fair play in football are required for this game to become actually possible to play

  9. HENRY'S "HAND OF GOD"

    Directory of Open Access Journals (Sweden)

    Željko Kaluđerović

    2014-04-01

    Full Text Available In this paper the author discusses the views and statements of the French football player Thierry Henry he gave after his illegal play during the playoff match between France and the Republic of Ireland to claim one of the final spots in the World Cup 2010 in South Africa. First, by controlling the ball with his hand before passing it on for the goal Henry has shown disregard for the constitutive rules of football. Then, by stating that he is "not a referee" he demonstrated that for some players rules are not inherent to football and that they can be relativized, given that for them winning is the goal of the highest ontological status. Furthermore, he has rejected the rules of sportsmanship, thus expressing his opinion that the opponents are just obstacles which have to be removed in order to achieve your goals. Henry's action has disrupted major moral values, such as justice, honesty, responsibility and beneficence. The rules of fair play have totally been ignored both in Henry's action and in the Football Association of France's unwillingness to comment on whether a replay should take place. They have ignored one of the basic principles stated in the "Declaration of the International Fair Play Committee", according to which, fair play is much more than playing to the rules of the game; it's about the attitude of the sportsperson. It's about respecting your opponent and preserving his or her physical and psychological integrity. Finally, the author believes that the rules, moral values and fair play in football are required for this game to become actually possible to play.

  10. Ion source developments for RNB production at Spiral / GANIL

    International Nuclear Information System (INIS)

    Villari, A.C.C.; Barue, C.; Gaubert, G.; Gibouin, S.; Huguet, Y.; Jardin, P.; Kandri-Rody, S.; Landre-Pellemoine, F.; Lecesne, N.; Leroy, R.; Lewitowicz, M.; Marry, C.; Maunoury, L.; Pacquet, J.Y.; Rataud, J.P.; Saint-Laurent, M.G.; Stodel, C.; Lichtenthaeler, R.; Angelique, J.C.; Orr, N.A.

    2000-01-01

    The first on-line production system for SPIRAL/GANIL (Radioactive Ion Production System with Acceleration on-Line) phase-I has been commissioned on the SIRa (Radioactive Ion Separator) test bench. Exotic multicharged noble gas ion beams have been obtained during several days. In parallel, a new ECRIS (Electron Cyclotron Resonance Ion Source) for mono-charged ions has also been developed. Preliminary, off-line results are presented. (authors)

  11. A new compiler for the GANIL Data Acquisition description

    International Nuclear Information System (INIS)

    Saillant, F.; Raine, B.

    1997-01-01

    An important feature of the GANIL Data Acquisition System is the description of the experiments by means of a language developed at GANIL. The philosophy is to attribute to each element (parameters, spectra, etc) an operational name which will be used at any level of the system. This language references a library of modules to free the user from the technical details of the hardware. This compiler has been recently entirely re-developed using technologies as the object-oriented language (C++) and object-oriented software development method and tool. This enables us to provide a new functionality or to support a new electronic module within a very short delay and without any deep modification of the application. A new Dynamic Library of Modules has been also developed. Its complete description is available on the GANIL WEB site http://ganinfo.in2p3.fr/acquisition/homepage.html. This new compiler brings a lot of new functionalities, among which the most important is the notion of 'register' whatever the module standard is. All the registers described in the module provider's documentation can now be accessed by their names. Another important new feature is the notion of 'function' that can be executed on a module. Also a set of new instructions has been implemented to execute commands on CAMAC crates. Another possibility of this new compiler is to enable the description of specific interfaces with GANIL Data Acquisition System. This has been used to describe the coupling of the CHIMERA Data Acquisition System with the INDRA one through a shared memory in the VME crate. (authors)

  12. Henry Gray, plagiarist.

    Science.gov (United States)

    Richardson, Ruth

    2016-03-01

    The first edition of Anatomy Descriptive and Surgical (1858) was greeted with accolades, but also provoked serious controversy concerning Henry Gray's failure to acknowledge the work of earlier anatomists. A review in the Medical Times (1859) accused Gray of intellectual theft. The journal took the unusual step of substantiating its indictment by publishing twenty parallel texts from Gray and from a pre-existing textbook, Quain's Anatomy. At the recent "Vesalius Continuum" conference in Zakynthos, Greece (2014) Professor Brion Benninger disputed the theft by announcing from the floor the results of a computer analysis of both texts, which he reported exonerated Gray by revealing no evidence of plagiarism. The analysis has not been forthcoming, however, despite requests. Here the historian of Gray's Anatomy supplements the argument set out in the Medical Times 150 years ago with data suggesting unwelcome personality traits in Henry Gray, and demonstrating the utility of others' work to his professional advancement. Fair dealing in the world of anatomy and indeed the genuineness of the lustre of medical fame are important matters, but whether quantitative evidence has anything to add to the discussion concerning Gray's probity can be assessed only if Benninger makes public his computer analysis. © 2015 Wiley Periodicals, Inc.

  13. The 1989 progress report of GANIL: Operations and machine studies

    International Nuclear Information System (INIS)

    1990-03-01

    The 1989 progress report of the GANIL (French acronym for National Large Accelerator of Heavy Ions) is presented. The studies and the operations performed on the accelerator during the 10th July to the 18th December are summarized. The machine's operating time, the time required in the starting step and the time available for the users are examined. Several technical studies performed are reported. The results obtained after the energy increase operation are satisfactory. The beam intensity was increased of about a factor of 10 [fr

  14. A new radiation safety control system for Ganil

    International Nuclear Information System (INIS)

    Saint Jores, P. De; Luong, T.T.; Martina, L.; Vega, G.

    1991-01-01

    A second generation radiation safety control system has been installed to upgrade the initial system which was not flexible enough to support new ion beams and new experimental conditions required by the accelerator operation. The main reasons which necessitated the improvement of the safety control system are presented. The new system which controls the Ganil accelerator from the first quarter of 1990 is described. It uses a star structured architecture, VME standard processors and front-end modules activated by pDOS operating system and high level language (C and Fortran) tasks, associated with enhanced resolution color displays for real time synoptics. (R.P.) 4 refs., 4 figs

  15. Publications of GANIL interdisciplinary researches 1983-2012

    International Nuclear Information System (INIS)

    2012-01-01

    After a brief presentation of some statistical information on the content and evolution of research topics during the period ranging from 1983 to 2012, this publication proposes a list of the numerous publications issued by the GANIL, a group of interdisciplinary researches. These publications addressed the following themes: atomic spectroscopy, physics of atomic collisions, physics of molecular collisions, ion transport in solids, duct, electron emission, pulverization, surface modification, effects in amorphous materials, effects in metals, effects in semiconductors, effects in superconductors, effects in oxides and carbides, effects in ionic crystals, effects in polymers, radiolysis at high linear energy transfer, radio-biology, nano materials and nano structuration, applications, miscellaneous topics, accreditation to supervise researches, research thesis

  16. SPIRAL at GANIL: Latest Results and Plans for the Future

    International Nuclear Information System (INIS)

    Villari, A.C.C.; Eleon, C.; Alves-Conde, R.; Angelique, J.C.; Barue, C.; Canet, C.; Dubois, M.; Dupuis, M.; Flambard, J.L.; Gaubert, G.; Jardin, P.; Lecesne, N.; Leherissier, P.; Lemagnen, F.; Leroy, R.; Maunoury, L.; Pacquet, J.Y.; Pellemoine, F.; Saint-Laurent, M.G.; Stodel, C.; Thomas, J.C.

    2007-01-01

    The first accelerated exotic beam of the SPIRAL (Production System of Radioactive Ion and Acceleration On-Line) facility at GANIL at Caen has been delivered for experiments in September 2001. After working for almost 5 years, 32 experiments were performed in the facility using exotic isotopes of helium, oxygen, neon, argon and krypton. The intensities of the radioactive beams increased since the first beam was delivered. Nominal intensity values are achieved for most of noble gas beams. Developments of new beams as well as the increasing of present intensities for a number of isotopes are being undertaken. In particular, in this contribution it is presented the first results obtained for the production of light alkali beams. Other developments are also envisaged in the close future

  17. Nuclear physics at Ganil. A compilation 1989-1991

    International Nuclear Information System (INIS)

    1991-01-01

    This compilation deals with experimental and theoretical work performed at GANIL for the 1989-1991 years about the nuclear structure and nuclear reactions. During this period, the accelerator performances have been strongly increased, as well for the delivered energies and intensities as for the span of accelerated ions. In the experimental areas, a totally new data acquisition system has been set up, and the adding of a Wien filter to the Lise spectrometer results now in a versatile and efficient isotope separator, called LISE III. The time structure and the large intensity of the beam were decisive in identifying, for the first time, kaon production in heavy ions collisions at the GANIL subthreshold energies. Nucleons have to undergo several collisions before inducing such a process, and the strange particle emission should be very sensitive to the physical conditions of the hot and compressed interacting zone. Lead and Uranium beams now available at the Fermi energy, have been used to study the nuclear disassembly of very large and heavy systems. New results have been obtained on the collective flow in heavy ion reactions, giving new insights on the Equation of State problematics. In the field of nuclear structure, the magnetic spectrometer SPEG, coupled with large particle or gamma detectors shed light on new aspects of the giant resonance excitations. Exotic nuclei are extensively studied, with a particular emphasis on the 11Li nucleus. A new method of mass measurement, using the CSS2 as a mass separator, has been successfully tested; it will greatly improve the accuracy achieved on intermediate and heavy nuclei. Last but not least, the theory group is actively working to include fluctuations in the description of the nuclear dynamics and to characterise the onset of the multifragmentation process in heavy ion collisions. Author index and publication list are added

  18. Present and future radioactive beam studies at GANIL. From SISSI to SPIRAL

    International Nuclear Information System (INIS)

    Guerreau, D.

    1996-01-01

    The present status of radioactive beam developments at GANIL is discussed. The emphasis is put on the construction of the new SPIRAL radioactive beam facility presently underway and of the main trends in physics. (author)

  19. Henry David Thoreau's Spiritual World

    Institute of Scientific and Technical Information of China (English)

    马云

    2013-01-01

    Henry David Thoreau was wholeheartedly in love with nature and he devoted almost all his life time to observation, appreciation and study of nature. Thus he formed a deep understanding of nature. In 1845, Thoreau began a two-year and two-month residence at Walden Pond. His life was lonely but full of fragrance. He wanted to live meaningfully, confront the essential facts of life and live a simple life. Based on the review of the literature related to this topic, this paper aims to study Henry David Thoreau’s spiritual world, especially reflected in his famous book-Walden.

  20. Radiobiology at GANIL: local project and others fields studied

    International Nuclear Information System (INIS)

    Anon.

    2001-01-01

    This article reviews the research that is led in the field of radiobiology using heavy ions at Ganil. Our first studies with heavy ions were mainly focused on chromosome rearrangements induced in irradiated human cells. We analyzed R-banded chromosome rearrangements in human lymphocytes irradiated with several ions having a wide range of linear energy transfer (LET). Damage increased with the fluence and LET but at the higher LET, damage decreased for fluences above 10 7 particles/cm 2 . Chromosome rearrangements of high complexity involve several breaks. DNA strand breaks are concentrated in localized areas and their complexity is greatly increased by high-LET radiations. Our study was mainly qualitative and we showed a clear shift and dispersion of comet distribution towards high tail moments when particle LET and fluence increased. The higher the LET, the greater the level of DNA breaks observed for the same fluence. Gamma rays were more effective in producing DNA breaks than all the ions, at least in the lower dose range. In addition to early damage, high-LET irradiation also induces delayed lesions, and genomic instability occurs after many generations in the progeny of irradiated cells. We observed delayed chromosome instability on human dermis fibroblasts exposed to heavy ions, neon, argon, and lead but not after gamma rays. Various fields of radiobiology are now explored by different research groups. One of the studies aims to detect locally multiple damage sites (LMDS) formed in DNA after exposure to heavy ions. (A.C.)

  1. Research at GANIL. A compilation 1996-1997

    Energy Technology Data Exchange (ETDEWEB)

    Balanzat, E.; Bex, M.; Galin, J.; Geswend, S. [eds.

    1998-12-01

    The present compilation gives an overview of experimental results obtained with the GANIL facility during the period 1996-1997. It includes nuclear physics activities as well as interdisciplinary research. The scientific domain presented here extends well beyond the traditional nuclear physics and includes atomic physics, condensed matter physics, nuclear astrophysics, radiation chemistry, radiobiology as well as applied physics. In the nuclear physics field, many new results have been obtained concerning nuclear structure as well as the dynamics of nuclear collisions and nuclear disassembly of complex systems. Results presented deal in particular with the problem of energy equilibration, timescales and the origin of multifragmentation. Nuclear structure studies using both stable and radioactive beams deal with halo systems, study of shell closures far from stability, the existence of nuclear molecules as well as measurements of fundamental data s half lives, nuclear masses, nuclear radii, quadrupole and magnetic moments. In addition to traditional fields of atomic and solid state physics, new themes such as radiation chemistry and radiobiology are progressively being tackled. (K.A.)

  2. The Life of Henry Eyring

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 17; Issue 7. The Life of Henry Eyring - From Mines to Molecules. Deepika Janakiraman. General Article Volume 17 Issue 7 July 2012 pp 625-634. Fulltext. Click here to view fulltext PDF. Permanent link:

  3. Henry Taube and Coordination Chemistry

    Science.gov (United States)

    dropdown arrow Site Map A-Z Index Menu Synopsis Henry Taube and Coordination Chemistry Resources with Professor of Chemistry, Emeritus, at Stanford University, received the 1983 Nobel Prize in Chemistry " there from 1940-41. "I became deeply interested in chemistry soon after I came to Berkeley,"

  4. Henry Morgenthau's voice in history.

    Science.gov (United States)

    Steiner, Pamela

    2015-01-01

    Henry Morgenthau (1856-1946) distinguished himself as the U.S. Ambassador to the Ottoman Empire, 1913-1916, and as the chairman of the League of Nations Refugee Settlement Commission (RSC) for Greece, 1923-24. I describe aspects of his early life that shaped the man he became, his accomplishments in these two posts, and his feelings about himself over time. At the end I briefly describe his attitude toward a possible Jewish state in Palestine.

  5. Use of an INGRES database to implement the beam parameter management at GANIL

    Energy Technology Data Exchange (ETDEWEB)

    Gillette, P.; Lecorche, E.; Lermine, P.; Maugeais, C.; Leboucher, Ch.; Moscatello, M.H.; Pain, P.

    1995-12-31

    Since the beginning of the operation driven by the new Ganil control system in February 1993, the relational database management system (RDBMS) Ingres has been more and more widely used. The most significant application relying on the RDBMS is the new beam parameter management which has been entirely redesigned. It has been operational since the end of the machine shutdown in July this year. After a short recall of the use of Ingres inside the control system, the organization of the parameter management is presented. Then the database implementation is shown, including the way how the physical aspects of the Ganil tuning have been integrated in such an environment. (author). 2 refs.

  6. Latest developments at GANIL for stable and radioactive ion beam production

    International Nuclear Information System (INIS)

    Jardin, P.; Barue, C.; Bajeat, O.; Canet, C.; Clement, E.; Cornell, J. C.; Delahaye, P.; Dubois, M.; Dupuis, M.; Flambard, J. L.; Fraanberg, H.; Frigot, R.; Leboucher, C.; Lecesne, N.; Lecomte, P.; Leherissier, P.; Lemagnen, F.; Leroy, R.; Maunoury, L.; Mery, A.

    2010-01-01

    In the frame of the SPIRAL II (Systeme de Production d'Ions Radioactifs Acceleres en Ligne Partie II) project, several developments of stable and radioactive ion production systems have been started up. In parallel, GANIL has the ambition to preserve the existing stable and radioactive beams and also to increase its range by offering new ones. In order to identify the best directions for this development, a new group called GANISOL has been formed. Its preliminary conclusions and the latest developments at GANIL are presented.

  7. Use of an INGRES database to implement the beam parameter management at GANIL

    Energy Technology Data Exchange (ETDEWEB)

    Gillette, P; Lecorche, E; Lermine, P; Maugeais, C; Leboucher, Ch; Moscatello, M H; Pain, P

    1996-12-31

    Since the beginning of the operation driven by the new Ganil control system in February 1993, the relational database management system (RDBMS) Ingres has been more and more widely used. The most significant application relying on the RDBMS is the new beam parameter management which has been entirely redesigned. It has been operational since the end of the machine shutdown in July this year. After a short recall of the use of Ingres inside the control system, the organization of the parameter management is presented. Then the database implementation is shown, including the way how the physical aspects of the Ganil tuning have been integrated in such an environment. (author). 2 refs.

  8. GANIL Workshop on Ion Sources; Journees Sources d'Ions

    Energy Technology Data Exchange (ETDEWEB)

    Leroy, Renan [Grand Accelerateur National d' Ions Lourds (GANIL), 14 - Caen (France)

    1999-07-01

    The proceedings of the GANIL Workshop on Ion Sources held at GANIL - Caen on 18-19 March 1999 contains 13 papers aiming at improving the old source operation and developing new types of sources for nuclear research and studies of ion physics. A number of reports are devoted to applications like surface treatment, ion implantation or fusion injection. The 1+{yields}n+ transformation, charged particle transport in ECR sources, addition of cesium and xenon in negative ion sources and other basic issues in ion sources are also addressed.

  9. Use of an INGRES database to implement the beam parameter management at GANIL

    International Nuclear Information System (INIS)

    Gillette, P.; Lecorche, E.; Lermine, P.; Maugeais, C.; Leboucher, Ch.; Moscatello, M.H.; Pain, P.

    1995-01-01

    Since the beginning of the operation driven by the new Ganil control system in February 1993, the relational database management system (RDBMS) Ingres has been more and more widely used. The most significant application relying on the RDBMS is the new beam parameter management which has been entirely redesigned. It has been operational since the end of the machine shutdown in July this year. After a short recall of the use of Ingres inside the control system, the organization of the parameter management is presented. Then the database implementation is shown, including the way how the physical aspects of the Ganil tuning have been integrated in such an environment. (author)

  10. On-line measurement of magnetic fields at GANIL; Mesures en ligne du champ magnetique du G.A.N.I.L

    Energy Technology Data Exchange (ETDEWEB)

    Lemarie, A

    2008-03-15

    On-line measurement of the magnetic fields of electromagnets at GANIL (France) was studied and developed. This type of measurement is necessary for it allows the adjustment and the monitoring of the parameters which control the transport of particle beams from the accelerators to the experimental vaults. The developments were based on nuclear magnetic resonance (NMR) magnetometers and Hall-effect magnetometers. The limitations of operating NMR probes in inhomogeneous fields required particular solutions. Techniques of positioning and appropriate compensation for field gradients were put in place. NMR probes and Hall-effect probes are integrated into the electronics for monitoring and control according to the defined standards at GANIL. The unit comprises instrumentation which perfectly meets the needs, particularly from the point of view of the measurement and the monitoring of the magnetic parameters. (author)

  11. Crystal assisted experiments for multi-disciplinary physics with heavy ion beams at GANIL

    International Nuclear Information System (INIS)

    Dauvergne, Denis

    2015-01-01

    We present a review of the channeling and blocking experiments that have been performed at GANIL during the 30 years of stable beam operation, with the strong support of the multi-disciplinary CIRIL-CIMAP laboratory. These experiments combine atomic physics, solid state physics and nuclear physics. (paper)

  12. Ion sources development at GANIL for radioactive beams and high charge state ions

    International Nuclear Information System (INIS)

    Leroy, R.; Barue, C.; Canet, C.; Dupuis, M.; Flambard, J.L.; Gaubert, G.; Gibouin, S.; Huguet, Y.; Jardin, P.; Lecesne, N.; Leherissier, P.; Lemagnen, F.; Pacquet, J.Y.; Pellemoine-Landre, F.; Rataud, J.P.; Saint-Laurent, M.G.; Villari, A.C.C.; Maunoury, L.

    2001-01-01

    The GANIL laboratory has in charge the production of ion beams for nuclear and non nuclear physics. This article reviews the last developments that are underway in the fields of radioactive ion beam production, increase of the metallic ion intensities and production of highly charges ion beams. (authors)

  13. TAPS experiments at Ganil: new developments, on-line results and data processing

    International Nuclear Information System (INIS)

    Lautridou, P.; Lefevre, F.; Marques, M.; Matulewicz, T.; Ostendorf, R.; Quebert, J.; Schutz, Y.

    1993-01-01

    The purpose of the present contribution is to show what the status of data analysis is only three months after TAPS has left GANIL. The authors also described briefly the data analysis package, they presently use and which has been specially developped for the TAPS experiments. One should notice that this package can be easily modified to suit any experimental situation. 8 figs

  14. First results of 35 MeV/u Kr + Au experiment at GANIL (Caen)

    International Nuclear Information System (INIS)

    Adloff, J.C.; Boishu, B.; Dalili, D.

    1984-01-01

    Preliminary results of a study of the Kr + Au breakup reaction at 35 MeV/u performed at GANIL are presented. Atomic number versus velocity distributions are presented for reaction fragments under various conditions. The results are explained by a kinematic model involving fast binary reactions followed by sequential decays by fission

  15. BD+43° 3654 - a blue straggler?

    Science.gov (United States)

    Gvaramadze, V. V.; Bomans, D. J.

    2008-07-01

    The astrometric data on the runaway star BD+43° 3654 are consistent with the origin of this O4If star in the center of the Cyg OB2 association, while BD+43° 3654 is younger than the association. To reconcile this discrepancy, we suggest that BD+43° 3654 is a blue straggler formed via a close encounter between two tight massive binaries in the core of Cyg OB2. A possible implication of this suggestion is that the very massive (and therefore apparently very young) stars in Cyg OB2 could be blue stragglers as well. We also suggest that the binary-binary encounter producing BD+43° 3654 might be responsible for ejection of two high-velocity stars (the stripped helium cores of massive stars) - the progenitors of the pulsars B2020+28 and B2021+51.

  16. CrossRef A new FEBIAD-type ion source for the upgrade of SPIRAL1 at GANIL

    CERN Document Server

    Chauveau, P; Babo, M; Bouzomita, H; Bajeat, O; Dubois, M; Frigot, R; Grinyer, G F; Grinyer, J; Jardin, P; Leboucher, C; Maunoury, L; Seiffert, C; Stora, T; Thomas, J C; Traykov, E

    2016-01-01

    The SPIRAL facility at GANIL is being upgraded with a new FEBIAD ion source in order to extend its production capabilities to condensable elements. The coupling of such an ion source with the present GANIL target was recently tested online at SPIRAL at nominal power (1200 W). The results are promising as the calculated yields are in the range of those extrapolated from previous measurements at lower power and sometimes higher. This experiment and its results are presented.

  17. Installation of a four movements goniometer in the ORION detector at Ganil

    International Nuclear Information System (INIS)

    Kirsch, R.

    1997-01-01

    This technical report describes a goniometer with four degrees of freedom and its driving and remote control system (movements, motors and electronic power systems, driving of step motors). This goniometer holds a monocrystal target which is used in the ORION detector at Ganil (Caen, France) for the E257 blocking lifetime experiment. Details about the technical specifications (functioning parameters, mechanical preciseness, angular resolution, reliability, etc..) and the instructions for use (PC for motors and PC for remote control) are given. (J.S.)

  18. Henrys Fork near Ashton, ID (YHEN)

    Data.gov (United States)

    Department of the Interior — Henrys Fork near Ashton, Idaho (YHEN) Sample Collection: Samples were collected near the USGS stream gage 13046000 (Latitude 44°04'11", Longitude 111°30'38" NAD83)....

  19. Development of target ion source systems for radioactive beams at GANIL

    Energy Technology Data Exchange (ETDEWEB)

    Bajeat, O., E-mail: bajeat@ganil.fr [GANIL, BP 55027, 14076 CAEN Cedex 05 (France); Delahaye, P. [GANIL, BP 55027, 14076 CAEN Cedex 05 (France); Couratin, C. [GANIL, BP 55027, 14076 CAEN Cedex 05 (France); LPC Caen, 6 bd Maréchal Juin, 14050 CAEN Cedex (France); Dubois, M.; Franberg-Delahaye, H.; Henares, J.L.; Huguet, Y.; Jardin, P.; Lecesne, N.; Lecomte, P.; Leroy, R.; Maunoury, L.; Osmond, B.; Sjodin, M. [GANIL, BP 55027, 14076 CAEN Cedex 05 (France)

    2013-12-15

    Highlights: • For Spiral 1, a febiad ion source has been connected to a graphite target. • For Spiral 2, an oven made with a carbon resistor is under development. • We made some measurement of effusion in the Spiral 2 target. • A laser ion source is under construction. -- Abstract: The GANIL facility (Caen, France) is dedicated to the acceleration of heavy ion beams including radioactive beams produced by the Isotope Separation On-Line (ISOL) method at the SPIRAL1 facility. To extend the range of radioactive ion beams available at GANIL, using the ISOL method two projects are underway: SPIRAL1 upgrade and the construction of SPIRAL2. For SPIRAL1, a new target ion source system (TISS) using the VADIS FEBIAD ion source coupled to the SPIRAL1 carbon target will be tested on-line by the end of 2013 and installed in the cave of SPIRAL1 for operation in 2015. The SPIRAL2 project is under construction and is being design for using different production methods as fission, fusion or spallation reactions to cover a large area of the chart of nuclei. It will produce among others neutron rich beams obtained by the fission of uranium induced by fast neutrons. The production target made from uranium carbide and heated at 2000 °C will be associated with several types of ion sources. Developments currently in progress at GANIL for each of these projects are presented.

  20. Study and realisation of a digital TDC in the framework of the GANIL trigger

    International Nuclear Information System (INIS)

    Boujrad, Abderrahman

    2001-01-01

    In nuclear physics, the interaction between the ion beam and the target produces a large amount of events. Some of these events have no interest for the studied physical phenomenon; the useful events are sorted using a trigger. We have studied and realized a new trigger suitable for the GANIL (Grand Accelerateur National d'Ions Lourds) experiments. After an overview of the triggers used up to now at GANIL, we give the main features of the new trigger (GANIL Master Trigger, GMT) such as modularity, universality and versatility. After a description of the trigger operating modes, we depict the trigger realization steps. The trigger informs about fired detectors in a beam to target collision but gives no information about timing, nevertheless the timing is a very important piece of information if the trigger analysis duration is several times greater than the beam period. We suggest a timing measurement structure (Time to Digital Converter, TDC) able to eliminate this imprecision. The dead time, the low level integration and the consumption constraints lead us to prefer a digital architecture based on a digital counter associated with delay lines. Simple equations are given in order to define the operating area of the TDC. This area depends on the clock duty cycle and on the delay line taps. Measures of Differential Non Linearity (DNL) for different time resolutions (1, 2, 5 and 10 ns) allow us to establish the limits of this System and to underline some solutions to improve these features. (author) [fr

  1. Far ultraviolet spectrophotometry of BD +28 4211

    Science.gov (United States)

    Cook, Timothy A.; Cash, Webster; Green, James C.

    1991-01-01

    The results are reported of a November 1989 rocket flight which recorded a flux-calibrated spectrum of BD +28 4211 from 912 to 1150 A with 1A resolution. BD +28 4211, an SdO-type star, is commonly used as an ultraviolet calibration source in the IUE wavelength band. The present work extends the useful range of this standard shortward of Lyman-alpha. Since previous experiments show marked disparity, this study can be useful in determining a standard in the 912 to 1216 A band.

  2. Bd/s -> mu+ mu- in ATLAS

    CERN Document Server

    Guenther, Jaroslav; The ATLAS collaboration

    2016-01-01

    The ATLAS Experiment has conducted a search for the rare decays of Bs and Bd into mu+mu-. 25 fb−1 of integrated luminosity of proton-proton collisions collected during LHC Run 1 were studied to provide new results presented in this talk. An upper limit is set on the branching ratio BR(Bd to mu+mu-) < 4.2×10−10 at 95% confidence level. For Bs, ATLAS measurement yields the branching ratio BR(Bs to mu+mu-)=(0.9+1.1−0.8)×10−9. The result is consistent with the Standard Model expectation and other available measurements.

  3. Obituary: Henry Emil Kandrup, 1955-2003

    Science.gov (United States)

    Merritt, David; Gottesman, Stephen T.

    2004-12-01

    Henry Emil Kandrup died on 18 October 2003 at his home in Gainesville Florida. Henry was a theoretical astrophysicist specializing in the application of chaotic dynamics to stellar systems. At the time of his death, Henry was a Professor at the University of Florida where he had taught for 13 years. Henry was born in Manhasset, New York on July 24, 1955 and spent most of his childhood in Great Neck. His parents, Jytte and Fred, were immigrants from Denmark where his father had worked as a silver smith. Henry was a precocious child, skipping both third and fifth grades. With the help of Sidney Spivack, a professor of sociology at Columbia University, his parents enrolled Henry in the Brooks Preparatory School in Andover, Massachusetts. After graduating at age 16, Henry enrolled at Cornell, transferring to Princeton the following year. Henry's parents adored their only child and worked hard to provide him with intellectual opportunities. Henry became an accomplished musician (organ, piano, French horn) and linguist (English, Danish, German) and was a passionate devotee of opera and ballet. Henry received his PhD in 1980 from the University of Chicago, where his thesis advisor was James Ipser. He taught at Oakland University in Michigan and Syracuse University in New York before coming to the University of Florida in 1990. Henry was sui generis. He shunned conventionality in his personal appearance and in his public demeanor, and always chose forthrightness and candor over polite silence. But to those of us who knew Henry well, his bluntness was a reflection of his intellectual consistency. Henry always said exactly what he thought, both in his published work and his public presentations, and never compromised himself for the sake of appearances. Nothing that he said or wrote was less than fully thought out. Henry's PhD thesis was entitled "Stochastic Problems in Stellar Dynamics," and most of his subsequent research was in this field. Motion in stellar systems can be

  4. Joseph Henry's Conception of Scientific Knowledge

    Science.gov (United States)

    Theerman, Paul

    1997-04-01

    Joseph Henry, America's premier physicist and physics teacher in the mid-nineteenth century, had decided views of scientific knowledge. These were expressed in two ways. First of all, scientific knowledge led to moral betterment. Thus the study of science was a morally good thing. This was not only because it led to the contemplation of God's creation, which was a standard reason justifying the study of science dating from the Scientific Revolution and even earlier. More importantly, the study of science itself was a moral discipline, imparting to scientists the habits and virtues of truthfulness, respect for others, care and diligence, and the discernment of meaningful patterns from experience. The moral ideals of science were expressed most strongly in Henry's upholding the international "Republic of Science"; conversely, cheapening science was a sign of moral failure. Second, for Henry and his generation, science provided a path to sure truth, separate from falsehood of both the politics and the quackery that characterized mid-century public life. Henry promoted this in his championing of the Smithsonian Institution a scientific establishment, against the ideas of others who wanted to make it a literary establishment or a training school for teachers. For Henry, the Smithsonian's scientific reputation would be established by relying on careful peer review in its publications, and supporting established scientists to write authoritative popular works. The purpose of both these activities was to raise the profile of science in the United States and further establish science and the scientific method as a guide to public life.

  5. Structure around the island of inversion with single-neutron knockout reactions at GANIL

    CERN Document Server

    Fernández-Domínguez, B; Patterson, N; Thomas, J S; Orr, N; Chartier, M; Catford, W; Achouri, N L; Angélique, J-C; Ashwood, N I; Banu, A; Bastin,B; Brown, J; Borcea, R; Franchoo, S; Freer, M; Gaudefroy, L; Laurent, B; Labiche, M; Lemmon, R C; Negoita, F; Paschalis, S; Paul, E S; Petri, M; Roussel-Chomaz, P; Staniou, M; Taylor, M J; Trache, L

    2010-01-01

    The nuclear structure of the 31Mg nucleus has been studied with the singleneutron knockout reaction. We report on the preliminary results of an experiment performed with the EXOGAM array coupled, for the first time, to the SPEG spectrometer at GANIL.We present a provisional result for the inclusive single-neutron knockout cross section of σinc= 90(5) mb. Preliminary exclusive cross sections for the measured bound states, including the ground state, are also presented. Finally, preliminary longitudinal momentum distributions for the ground state and first excited state are also shown. These results are compared to Monte Carlo Shell-Model calculations in the sd-pf region.

  6. LIONS: a new set of Fortran 90 codes for the SPIRAL project at GANIL

    International Nuclear Information System (INIS)

    Bertrand, P.

    1994-01-01

    A set of new computer programs developed at GANIL is presented; these codes are used to study different parts of the SPIRAL project (a new radioactive ion beam facility), and particularly the dynamics in the CIME cyclotron, its injection inflector, and the new extraction system of the ECR ion sources. Three important modules are described: CHA3D for the evaluation of 3D electric fields with or without space charge effects, LIONS for the motion of ions and EXTRACT for the ECRIS extraction. These modules are written in Fortran 90 in a ''data parallel scheme''. They work either on UNIX workstations or parallel and vectorial computers. (author). 5 figs., 5 refs

  7. LIONS: a new set of Fortran90 codes for the SPIRAL project at GANIL

    International Nuclear Information System (INIS)

    Bertrand, P.

    1995-01-01

    In this paper a set of new computer programs developed at GANIL is presented. These codes are used to study different parts of the SPIRAL project, in particular the dynamics in the CIME cyclotron and the new extraction system of the ECR ion sources. Three important modules are described: CHA3D for the evaluation of 3D electric fields with or without space charge effects, LIONS for the motion of ions and EXTRACT for the ECRIS extraction. These modules are written in Fortran90 in a ''data parallel scheme''. They work either on UNIX workstations or parallel and vectorial computers. (orig.)

  8. First results with the 4π charged particle detector INDRA at GANIL

    International Nuclear Information System (INIS)

    Dayras, R.

    1995-01-01

    After a three year construction period, the 4π charged particle detector INDRA took its first data at GANIL, during the spring of 1993. After a brief description of the detector characteristics, an overview of the ongoing scientific program is given. The general trend of the data are discussed. For the first time, the energy threshold for the full vaporization of a nuclear system into neutrons and Z=1 and 2 isotopes has been determined for the 36 Ar + 58 Ni reaction. For this system, this threshold is observed for an incident energy of about 50 A.MeV. (author). 18 refs., 6 figs

  9. Kolmanda maailma raudteekunn / Henry Posner ; interv. Krister Kivi

    Index Scriptorium Estoniae

    Posner, Henry

    2005-01-01

    Raudteeärimees Henry Posner III, kes kuulub ka Eesti Raudtee omanikeringi, oma äritegevusest, sealhulgas investeeringutest Eestisse. Suhtumisest raudteeturu avamisse. Lisa: Henry Posner mängib rongidega maailma hämarates nurkades

  10. Robert Henry Thurston: Professionalism and Engineering Education

    Science.gov (United States)

    Nienkamp, Paul

    2016-01-01

    Robert Henry Thurston is presented in this article. He provides one the most significant examples of professionalizing engineering through innovative education and promoting scientific education practices in the late nineteenth century. The son of a draftsmen and steam engine mechanic, Thurston spent his early years in Providence, Rhode Island.…

  11. Antoine-Henri Jomini: A Bibliographical Survey.

    Science.gov (United States)

    Alger, John I.

    Although the writings of Antoine-Henri Jomini influenced military thought during the 19th and 20th centuries, the obscurity of their publishing history has led to misunderstandings of the development and substance of Jomini's thought. This review attempts to (1) point out the continuity of his thought on the conduct of war, and (2) provide an…

  12. Translating China : Henri Borel (1869-1933)

    NARCIS (Netherlands)

    Heijns, A.J.

    2016-01-01

    This thesis investigates how Dutch sinologist Henri Borel ‘translated’ China, by examining his renditions of Chinese literature and the writings about China that he produced over a period of forty years. Borel studied Hokkien Chinese at Leiden University and in Xiamen toward a career as Chinese

  13. Transcendentalism and Henry Barnard's "School Architecture"

    Science.gov (United States)

    Rothfork, John

    1977-01-01

    Sketches the intellectual and sociological climate that led Henry Barnard to advocate Greek Revival architecture for school buildings, takes a look at why this style and its implicit values were popular in the era between 1820-1860, and examines a few of the plans in Barnard's "School Architecture" (1838-48). (Author/RK)

  14. The Ideas of Henry Jenkins and Libraries

    Science.gov (United States)

    Anderson, Byron

    2008-01-01

    Henry Jenkins, director of the Comparative Media Studies Program at the Massachusetts Institute of Technology and keynote speaker at the 2007 American Library Association's "Gaming, Learning and Libraries Symposium" in Chicago is a visionary leader in the areas of new media and media convergence. In a white paper on digital media and learning…

  15. A new open GKS-based supervision system in use at GANIL

    International Nuclear Information System (INIS)

    Lecorche, E.

    1990-01-01

    Since the beginning of 1989, a new supervision system has been added to the GANIL control system in order to get a better view of data handled by programmable controllers. This supervisory system has been designed around software named IMAGIN, provided by the French company Sferca. IMAGIN runs on VAX/VMS workstations and its graphic capabilities are based on the GKS IIc standard. It consists of software modules, including a graphic editor and a 'configurer' used to create dynamic objects associated with external variables. The real-time display achieved by an 'animator' process is synchronized with user software programs by means of mailboxes. This gives the whole system the capability of meeting any specific requirement. Moreover, this supervisory system is capable of controlling the programmable controllers as well as any processor which can be reached from the workstations. This paper describes the main features of IMAGIN software and then emphasizes some implementations which have been carried out at GANIL, to supervise either the programmable controllers or the existing control system. (orig.)

  16. Contaminant Monitoring Strategy for Henrys Lake, Idaho

    Energy Technology Data Exchange (ETDEWEB)

    John S. Irving; R. P. Breckenridge

    1992-12-01

    Henrys Lake, located in southeastern Idaho, is a large, shallow lake (6,600 acres, {approx} 17.1 feet maximum depth) located at 6,472 feet elevation in Fremont Co., Idaho at the headwaters of the Henrys Fork of the Snake River. The upper watershed is comprised of high mountains of the Targhee National Forest and the lakeshore is surrounded by extensive flats and wetlands, which are mostly privately owned. The lake has been dammed since 1922, and the upper 12 feet of the lake waters are allocated for downriver use. Henrys Lake is a naturally productive lake supporting a nationally recognized ''Blue Ribbon'' trout fishery. There is concern that increasing housing development and cattle grazing may accelerate eutrophication and result in winter and early spring fish kills. There has not been a recent thorough assessment of lake water quality. However, the Department of Environmental Quality (DEQ) is currently conducting a study of water quality on Henrys Lake and tributary streams. Septic systems and lawn runoff from housing developments on the north, west, and southwest shores could potentially contribute to the nutrient enrichment of the lake. Many houses are on steep hillsides where runoff from lawns, driveways, etc. drain into wetland flats along the lake or directly into the lake. In addition, seepage from septic systems (drainfields) drain directly into the wetlands enter groundwater areas that seep into the lake. Cattle grazing along the lake margin, riparian areas, and uplands is likely accelerating erosion and nutrient enrichment. Also, cattle grazing along riparian areas likely adds to nutrient enrichment of the lake through subsurface flow and direct runoff. Stream bank and lakeshore erosion may also accelerate eutrophication by increasing the sedimentation of the lake. Approximately nine streams feed the lake (see map), but flows are often severely reduced or completely eliminated due to irrigation diversion. In addition, subsurface

  17. SPIRAL2 at GANIL: At the Dawn of a New Era

    International Nuclear Information System (INIS)

    Gales, S.

    2010-01-01

    The exploration of unknown region of the nuclear mass chart, in particular, the neutron rich side, raised new and challenging physics issues in the understanding of nuclei far from stability. The physics of weakly bound systems, the appearance of shell quenching, the interface with astrophysical problems prompted the study of new generation of ''Rad ioactive Beam Facilities'' with high luminosity and the development of associated new experimental tools.GANIL presently offers unique opportunities in nuclear physics and many other fields. With the construction of SPIRAL2 over the next few years, GANIL is in a good position to retain its world-leading capability even though it faces strong competition from new and upgraded ISOL and fragmentation facilities. As selected by the ESFRI committee, the next generation of ISOL facility in Europe is represented by the SPIRAL2 project to be built at GANIL (Caen, France). SPIRAL2 is based on a high power, CW, superconducting LINAC, delivering 5 mA of deuteron beams at 40 MeV (200 KW) directed on a C converter+ Uranium target and producing therefore more 10 13 fissions/s. The expected radioactive beams intensities in the mass range from A = 60 to A = 140, will surpass by two order of magnitude any existing facilities in the world. These unstable atoms will be available at energies between few KeV/n to 15 MeV/n. The same driver will accelerate high intensity (100* A to 1 mA), heavier ions (Ar up to Xe) at maximum energy of 14 MeV/n.In applied areas SPIRAL2 is considered as a powerful variable energy neutron source. The Neutrons For Science collaboration (NFS) is proposing a physics program on fission induced by fast neutrons as well as fusion studies on materials.Under the 7FP program of European Union called 'Preparatory phase', the SPIRAL2 project has been granted a budget of about 4 MEuro to build up an international consortium around this new venture. Regarding the future physics program a call for Letter of intents has been

  18. SPIRAL2 at GANIL: At the Dawn of a New Era

    Science.gov (United States)

    Gales, S.

    2010-04-01

    The exploration of unknown region of the nuclear mass chart, in particular, the neutron rich side, raised new and challenging physics issues in the understanding of nuclei far from stability. The physics of weakly bound systems, the appearance of shell quenching, the interface with astrophysical problems prompted the study of new generation of "Rad ioactive Beam Facilities" with high luminosity and the development of associated new experimental tools. GANIL presently offers unique opportunities in nuclear physics and many other fields. With the construction of SPIRAL2 over the next few years, GANIL is in a good position to retain its world-leading capability even though it faces strong competition from new and upgraded ISOL and fragmentation facilities. As selected by the ESFRI committee, the next generation of ISOL facility in Europe is represented by the SPIRAL2 project to be built at GANIL (Caen, France). SPIRAL2 is based on a high power, CW, superconducting LINAC, delivering 5 mA of deuteron beams at 40 MeV (200 KW) directed on a C converter+ Uranium target and producing therefore more 1013 fissions/s. The expected radioactive beams intensities in the mass range from A = 60 to A = 140, will surpass by two order of magnitude any existing facilities in the world. These unstable atoms will be available at energies between few KeV/n to 15 MeV/n. The same driver will accelerate high intensity (100* A to 1 mA), heavier ions (Ar up to Xe) at maximum energy of 14 MeV/n. In applied areas SPIRAL2 is considered as a powerful variable energy neutron source. The Neutrons For Science collaboration (NFS) is proposing a physics program on fission induced by fast neutrons as well as fusion studies on materials. Under the 7FP program of European Union called*Preparatory phase*, the SPIRAL2 project has been granted a budget of about 4 M€ to build up an international consortium around this new venture. Regarding the future physics program a call for Letter of intents has been

  19. Elevated Corticosterone Levels and Changes in Amphibian Behavior Are Associated with Batrachochytrium dendrobatidis (Bd Infection and Bd Lineage.

    Directory of Open Access Journals (Sweden)

    Caitlin R Gabor

    Full Text Available Few studies have examined the role hormones play in mediating clinical changes associated with infection by the parasite Batrachochytrium dendrobatidis (Bd. Glucocorticoid (GC hormones such as corticosteroids (CORT regulate homeostasis and likely play a key role in response to infection in amphibians. We explore the relationship between CORT release rates and Bd infection in tadpoles of the common midwife toad, Alytes obstetricians, using a non-invasive water-borne hormone collection method across seven populations. We further examined whether tadpoles of A. muletensis infected with a hypervirulent lineage of Bd, BdGPL, had greater CORT release rates than those infected with a hypovirulent lineage, BdCAPE. Finally, we examined the relationship between righting reflex and CORT release rates in infected metamorphic toads of A. obstetricans. We found an interaction between elevation and Bd infection status confirming that altitude is associated with the overall severity of infection. In tandem, increasing elevation was associated with increasing CORT release rates. Tadpoles infected with the hypervirulent BdGPL had significantly higher CORT release rates than tadpoles infected with BdCAPE showing that more aggressive infections lead to increased CORT release rates. Infected metamorphs with higher CORT levels had an impaired righting reflex, our defined experimental endpoint. These results provide evidence that CORT is associated with an amphibian's vulnerability to Bd infection, and that CORT is also affected by the aggressiveness of infection by Bd. Together these results indicate that CORT is a viable biomarker of amphibian stress.

  20. Henri Fayol and Zero Tolerance Policies

    OpenAIRE

    Lee SCHIMMOELLER

    2012-01-01

    Zero tolerance policies have been increasingly popular in both education and business. Henri Fayol was the one of the earliest and influential thinkers in modern management theory. He defined management as a body of knowledge and defined his 14 administrative principles. It is an interesting exercise to apply Fayol’s teachings to the theory of zero tolerance and attempt to determine what Fayol would think of this new management technique.

  1. Henry P. McKean Jr. selecta

    CERN Document Server

    Moerbeke, Pierre; Moll, Victor

    2015-01-01

    This volume presents a selection of papers by Henry P. McKean, which illustrate the various areas in mathematics in which he has made seminal contributions. Topics covered include probability theory, integrable systems, geometry and financial mathematics. Each paper represents a contribution by Prof. McKean, either alone or together with other researchers, that has had a profound influence in the respective area.

  2. CATS, a low pressure multiwire proportional chamber for secondary beam tracking at GANIL

    CERN Document Server

    Ottini-Hustache, S; Auger, F; Musumarra, A; Alamanos, N; Cahan, B; Gillibert, A; Lagoyannis, A; Maillard, O; Pollacco, E; Sida, J L; Riallot, M

    1999-01-01

    A beam detector system, CATS (Chambre A Trajectoires de Saclay), was designed to provide event-by-event particle tracking in experiments with radioactive beams at GANIL. It consists of two low pressure multiwire proportional chambers with one plane of anode wires placed between two cathode planes (active area: 70x70 mm sup 2), respectively segmented into 28 vertical or horizontal strips (2.54 mm wide). The anode wires deliver a time signal allowing a time of flight measurement with an accuracy between 440 ps and 1.2 ns, depending on the energy loss of incident particles in the detector. The cathode strips are individually read out and the position of incoming particles is reconstructed using a charge centroid finding algorithm. A spatial resolution of 400 mu m (700 mu m) was achieved during in beam experiment, with a counting rate of 1.5x10 sup 5 (10 sup 6) particles per second. (author)

  3. Characterization and performances of DOSION, a dosimetry equipment dedicated to radiobiology experiments taking place at GANIL

    Energy Technology Data Exchange (ETDEWEB)

    Boissonnat, Guillaume, E-mail: boissonnat@lpccaen.in2p3.fr [LPC (Normandie Univ-ENSICAEN-UNICAEN-CNRS/IN2P3), 6 Bd Maréchal Juin, 14050 Caen (France); Fontbonne, Jean-Marc [LPC (Normandie Univ-ENSICAEN-UNICAEN-CNRS/IN2P3), 6 Bd Maréchal Juin, 14050 Caen (France); Balanzat, Emmanuel [CIMAP (CEA/DSM-CNRS/INP-ENSICAEN-UNICAEN), Bd Henri Becquerel, 14076 Caen (France); Boumard, Frederic; Carniol, Benjamin [LPC (Normandie Univ-ENSICAEN-UNICAEN-CNRS/IN2P3), 6 Bd Maréchal Juin, 14050 Caen (France); Cassimi, Amine [CIMAP (CEA/DSM-CNRS/INP-ENSICAEN-UNICAEN), Bd Henri Becquerel, 14076 Caen (France); Colin, Jean; Cussol, Daniel; Etasse, David; Fontbonne, Cathy [LPC (Normandie Univ-ENSICAEN-UNICAEN-CNRS/IN2P3), 6 Bd Maréchal Juin, 14050 Caen (France); Frelin, Anne-Marie [GANIL (CEA/DSM-CNRS/IN2P3), Bd Henri Becquerel, 14076 Caen (France); Hommet, Jean; Salvador, Samuel [LPC (Normandie Univ-ENSICAEN-UNICAEN-CNRS/IN2P3), 6 Bd Maréchal Juin, 14050 Caen (France)

    2017-06-01

    Currently, radiobiology experiments using heavy ions at GANIL (Grand Accélérateur National d′Ions Lourds) are conducted under the supervision of the CIMAP (Center for research on Ions, MAterials and Photonics). In this context, a new beam monitoring equipment named DOSION has been developed. It allows to perform measurements of accurate fluence and dose maps in near real time for each biological sample irradiated. In this paper, we present the detection system, its design, performances, calibration protocol and measurements performed during radiobiology experiments. This setup is currently available for any radiobiology experiments if one wishes to correlate one's own sample analysis to state-of-the-art dosimetric references.

  4. Capacitive beam position monitors and automatic beam centering in the transfer lines of Ganil

    International Nuclear Information System (INIS)

    Gudewicz, P.; Petit, E.

    1991-01-01

    A non-interceptive beam position monitor, made of four capacitive electrodes, has been designed at GANIL in order to allow a permanent measurement of the ion beam position over a large intensity range (50 enA to 10 eμA). Signal processing is based on a 10 kHz heterodyne and on an amplitude to phase conversion in order to measure the beam position. An immediate application of these monitors is the automatic beam centering. For this, two algorithms have been developed using the information on the center of gravity given by the beam position monitors which is then fed back to the steerers, an iterative method and a variational method. Both methods have been used on a section of beam line and have given similar and encouraging results. The next step is to center the beam on the completely equipped line. (author) 4 refs., 2 figs., 1 tab

  5. Project ''OAE'' at Ganil, a project for increasing the heavy ion energies

    International Nuclear Information System (INIS)

    Ferme, J.

    1986-10-01

    GANIL is composed of three cyclotrons connected in series, with a stripper located between the last two stages. The general parameters have been chosen to fit the characteristics of the PIG ion source. With the advent of ECR sources, which can produce efficiently ions of higher charge state, an optimization of the system has been considered which will result in an increase of the energy range of medium and heavy ions. A few modifications of the machine are necessary and should be carefully prepared so as to minimize the duration of the shut-down planned at the beginning of 1989. Moreover, a systematic study of the axial injection of the first cyclotron has been undertaken in order to improve the intensity of the injected beam with respect to space charge

  6. Astrometric studies of the regions BD + 17 degree 4946, BD -5 degree 3071, and Ross 730-1

    International Nuclear Information System (INIS)

    Russell, J.; Gatewood, G.

    1975-01-01

    Positions, proper motions, and absolute parallaxes were found for 46 stars in the regions of BD +17 degree4946, BD -5 degree3071, and Ross 730-1. BD +17 degree4946 showed some evidence of irregular variations in position and magnitude. The residuals for Ross 730-1 were used in a preliminary study to test for an appropriate weighting system; a weak weighting system was indicated. (auth)

  7. Widespread occurrence of bd in French Guiana, South America.

    Directory of Open Access Journals (Sweden)

    Elodie A Courtois

    Full Text Available The amphibian chytrid fungus Batrachochytrium dendrobatidis (Bd is a purported agent of decline and extinction of many amphibian populations worldwide. Its occurrence remains poorly documented in many tropical regions, including the Guiana Shield, despite the area's high amphibian diversity. We conducted a comprehensive assessment of Bd in French Guiana in order to (1 determine its geographical distribution, (2 test variation of Bd prevalence among species in French Guiana and compare it to earlier reported values in other South American anuran species (http://www.bd-maps.net; 123 species from 15 genera to define sentinel species for future work, (3 track changes in prevalence through time and (4 determine if Bd presence had a negative effect on one selected species. We tested the presence of Bd in 14 species at 11 sites for a total of 1053 samples (306 in 2009 and 747 in 2012. At least one Bd-positive individual was found at eight out of 11 sites, suggesting a wide distribution of Bd in French Guiana. The pathogen was not uniformly distributed among the studied amphibian hosts, with Dendrobatidae species displaying the highest prevalence (12.4% as compared to Bufonidae (2.6 % and Hylidae (1.5%. In contrast to earlier reported values, we found highest prevalence for three Dendrobatidae species and two of them displayed an increase in Bd prevalence from 2009 to 2012. Those three species might be the sentinel species of choice for French Guiana. For Dendrobates tinctorius, of key conservation value in the Guiana Shield, smaller female individuals were more likely to be infected, suggesting either that frogs can outgrow their chytrid infections or that the disease induces developmental stress limiting growth. Generally, our study supports the idea that Bd is more widespread than previously thought and occurs at remote places in the lowland forest of the Guiana shield.

  8. Henri Tamm : algul küsiti mult kogu aeg autogrammi / Henri Tamm ; interv. Ada Kallam

    Index Scriptorium Estoniae

    Tamm, Henri

    2005-01-01

    Draamaseriaali "Kodu keset linna" lapsnäitleja. Lisaks kolleegid Henrist : M. Veinmann "Tekst on tal esimesena peas", K. Maibaum "Võrdväärne partner suurtele". Artikkel pealkirjaga "Henri Tamm : nüüd saan veidi puhkust" : Linnaleht nr. 22, 3. juuni 2005, A2-A3

  9. HENRY C. WALLICH: A THIRD GENERATION BANKER

    Directory of Open Access Journals (Sweden)

    Saul Engelbourg

    2001-01-01

    Full Text Available Born in Germany and descendant of a wealthy banking family, Henry C. Wallich emigrated to the United States like others of Jewish ancestry who fled during the 1930s. A professor of money and banking at Yale for two decades, Wallich capped his career as a Governor of the Federal Reserve. During the stagflation of the late 1960s, Wallich, a dissenter, tirelessly advocated tighter monetary policy to stem inflation. Always a scholar, Wallich published extensively; he also served as the Fed’s public spokesman. Owing to his Harvard doctorate and his eminence as an economist, Wallich knew everyone worth knowing in the economics profession.

  10. Henri Becquerel: the discovery of radioactivity

    International Nuclear Information System (INIS)

    Allisy, A.

    1996-01-01

    This paper recalls the history of the Becquerel family, the fascinating time of the discovery of radioactivity as well as some important related research published before the radium age. Henri Becquerel was the third in the line of a family of scientists which extended over more than a hundred years. Following in the footsteps of his father and grandfather gave him a thorough grounding in scientific research methods. Science at the turn of the century was very exciting, the discovery of X rays had just been announced and scientists everywhere were hoping to discover new phenomena. (author)

  11. Henry Fuseli’s Alternative Classicism

    Directory of Open Access Journals (Sweden)

    Martin Myrone

    2015-12-01

    Full Text Available The review considers Andrei Pop’s Antiquity, Theatre & The Painting of Henry Fuseli. This argues for the history painter and writer Fuseli as an exemplary ‘Neopagan’, a term coined by Pop to refer to the new sense of cultural pluralism and historical relativism which emerged in Europe after the discovery of the remains of Pompeii and Herculaneum in 1748. While this perspective offers a fresh view of the artist, relating him to the emergence of modernity, and illuminates some important aspects of his work, the reviewer also suggests that the monographic focus risks re-asserting a sense of Fuseli’s exceptionalism.

  12. Heavy ions reactions at GANIL energies: the use of LISE telescopic mode for the small angle measurements

    International Nuclear Information System (INIS)

    Bacri, C.O.

    1989-01-01

    The use of heavy ions at GANIL energies leads to a concentration of the reaction products in the forward direction. Measurements have to be performed at and around 0 degree and with an accuracy around one milliradian. The angular selection (after the two dipoles) is performed after a magnetic rigidity one (between the two dipoles). The double sorting does allow measurements close to the beam in magnetic rigidity and in angle. TRANSPORT calculations show that the LISE spectrometer of GANIL can be used in telescopic mode. Experiments with a 44 MeV per nucleon Argon beam on C, Al, Ni and Au targets are performed. The identification of all the detected ions allowed the obtention of angular distributions at and around 0 degree with the required accuracy. This study is completed by a theoretical approach of the thermodynamical evolution based on an extended quantal mean field theory in which a collision-like term simulates residual interaction effects [fr

  13. 78 FR 11089 - Special Conditions: Bombardier Aerospace, Model BD-500-1A10 and BD-500-1A11 Airplanes; Sidestick...

    Science.gov (United States)

    2013-02-15

    ...; Special Conditions No. 25-477-SC] Special Conditions: Bombardier Aerospace, Model BD-500-1A10 and BD-500... special conditions. SUMMARY: These special conditions are issued for the Bombardier Aerospace Model BD-500...: Background On December 10, 2009, Bombardier Aerospace applied for a type certificate for their new Model BD...

  14. 77 FR 69568 - Special Conditions: Bombardier Aerospace, Model BD-500-1A10 and BD-500-1A11 Airplanes; Sidestick...

    Science.gov (United States)

    2012-11-20

    ... Aerospace, Model BD-500-1A10 and BD-500-1A11 Airplanes; Sidestick Controllers AGENCY: Federal Aviation... conditions for the Bombardier Aerospace Model BD-500-1A10 and BD-500-1A11 airplanes. These airplanes will... on the comments we receive. Background On December 10, 2009, Bombardier Aerospace applied for a type...

  15. 78 FR 75511 - Special Conditions: Bombardier Inc., Models BD-500-1A10 and BD-500-1A11 Series Airplanes...

    Science.gov (United States)

    2013-12-12

    ... Inc., Models BD-500-1A10 and BD- 500-1A11 Series Airplanes; Electronic Flight Control System: Control... Inc. Models BD-500-1A10 and BD-500-1A11 series airplanes. These airplanes will have a novel or unusual... comments, data, or views. The most helpful comments reference a specific portion of the special conditions...

  16. Henry James – Modern Theoretician of Narration

    Directory of Open Access Journals (Sweden)

    Alexandra - Denisa IGNA

    2013-01-01

    Full Text Available Henry James, properly named world writer, was one of the first modern novelists, with an exigent writing conscience. The American writer subverted the prejudgement of the omniscient author in favour of the narration which is centred on the characters’ point of view, thus modernising the novel before V. Woolf, Huxley, Thomas Mann, or in our case Camil Petrescu and G. Călinescu. Some bio-bibliographical information familiarises the reader with the life and work of this writer. The larger part of the article is dedicated to a case study of the novel with the metaphorical title: The Figure in the Carpet, where Henry James tries to illustrate in an artistic manner his conception regarding the profundity and ineffability of the literary creation. The conclusion which the author reaches, alternating the familiar plan of the relationship between a married couple with the esthetical plan, is that the relationship between writer and his work represents an act of fully intimacy, just like a ceremony that takes place in the wedding night

  17. Henry VIII, McLeod syndrome and Jacquetta's curse.

    Science.gov (United States)

    Stride, P; Lopes Floro, K

    2013-01-01

    The mental decline of King Henry VIII from being a jovial, charismatic and athletic young man into an increasingly paranoid, brutal tyrant in later life, ever more concerned at his lack of one or more male heirs, has attracted many medical diagnostic theories. Previous hypotheses have included diabetes, syphilis and hypothyroidism, among others. However, these inadequately explain Henry's failure to produce a male heir, despite multiple pairings. The latest postulated diagnoses for Henry are the coexistence of both Kell blood group antigenicity (possibly inherited from Jacquetta Woodville, Henry's maternal great grandmother) causing related impaired fertility, and McLeod syndrome, causing psychotic changes. As the mutated McLeod protein of the syndrome significantly reduces the expression, effectively inactivating the Kell antigen, we critically review this theory, examining in detail the pathophysiology of these conditions and assessing the genealogy of Henry VIII and its effect in subsequent generations.

  18. Putting in action the 4π γ multidetector TAPS at Ganil

    International Nuclear Information System (INIS)

    Merrouch, R.

    1991-04-01

    The study of the hard photons production originating in heavy ion collisions from bremstrahlung radiation or from the decay of neutral mesons like π 0 and η, is an original approach towards the understanding of the dynamics of nuclear reactions and of the behaviour of nuclear matter. The 4 π multidetector TAPS has been constructed for that purpose. Many european laboratories joined their efforts to achieve the equipment. It is therefore also foreseen to use it at various accelerators delivering heavy ions between 10 and 2000 MeV/u and electrons of up to 800 MeV. In the first part of this work, the reasons for the choice of TAPS are described. The second part describes the particular mechanical set up used at GANIL together with its electronics and data acquisition system. In the third part the methods for simulating the response of the detectors are explained. The fourth and last part contains the data analysis of an experiment using the reaction 129 Xe + 197 Au at 44 MeV/u. The first results are very stimulating and demonstrate that TAPS is well suited to the detection of photons in an important hadronic noise. It has also been demonstrated that the detection of very rare events like subthreshold pions, is possible thanks to the excellent performances of TAPS [fr

  19. High intensity metallic ion beams from an ecr ion source at GANIL

    International Nuclear Information System (INIS)

    Leherissier, P.; Barue, C.; Canet, C.; Dupuis, M.; Flambard, J.L.; Gaubert, G.; Gibouin, S.; Huguet, Y.; Jardin, P.; Lecesne, N.; Lemagnen, F.; Leroy, R.; Pacquet, J.Y.; Pellemoine-Landre, F.; Rataud, J.P.; Jaffres, P.A.

    2001-01-01

    In the recent years, progress concerning the production of high intensity of metallic ions beams ( 58 Ni, 48 Ca, 76 Ge) at Ganil have been performed. The MIV0C method has been successfully used to produce a high intensity nickel beam with the ECR4 ion source: 20 eμA of 58 Ni 11+ at 24 kV extraction voltage. This beam has been maintained for 8 days and accelerated up to 74.5 MeV/u by our cyclotrons with a mean intensity of 0.13 pμA on target. This high intensity, required for experiment, led to the discovery of the doubly magic 48 Ni isotope. The oven method has been first tested with natural metallic calcium on the ECR4 ion source, then used to produce a high power beam (740 W on target i.e. 0.13 pμA accelerated up to 60 MeV/u) of 48 Ca still keeping a low consumption (0.09 mg/h). A germanium beam is now under development, using the oven method with germanium oxide. The ionization efficiencies have been measured and compared. (authors)

  20. Obituary: Henry Albers (1925-2009)

    Science.gov (United States)

    Chromey, Fred

    2011-12-01

    Henry Albers, professor of astronomy at Vassar College for over thirty years, died March 29, 2009, in Fairhope, Alabama. For his work at Vassar, where he held the Maria Mitchell Chair, Albers received the first Maria Mitchell Women in Science Award for his inspiration of women astronomers. He said "In the final analysis it is the students who bring the joy into teaching." As a professional astronomer, Albers did observational work on Galactic structure in the southern Milky Way, and on the structure of the Magellanic Clouds. In retirement, Albers published Maria Mitchell - A Life in Journals and Letters, the firsthand account of America's first woman astronomer. Albers's research was on photographic near-infrared spectroscopy of red giant stars in the southern Milky Way, some proper motion studies, and on the structure of the Magellanic Clouds. A series of seven NSF grants supported his six trips to Chile to make spectroscopic observations, as well as his sabbatical collaborations at Minnesota, Leiden, and the Royal Observatory in Edinburgh. Henry Albers arrived at Vassar in 1958, to find an astronomy program that had been recently absorbed by the physics department, and that was suffering neglect after the retirement of Maud Makemson. For the next 31 years, with incredible energy -- he sometimes taught seven courses a year -- he built the astronomy program into one double in size (from one to two tenure lines), whose th century facilities have been replaced with a st century observatory. For a remarkable stretch of 20-some-years, Albers and physicist Bob Stearns, with considerable grace, alternated chairmanship of the joint department of physics and astronomy. Henry Albers was a devoted citizen of Vassar College and an enthusiastic participant in the process of faculty governance at that institution. He would have been the first to concede that his enthusiasm was sometimes excessive, and that his contributions at faculty meetings occasionally failed to move the

  1. VoxHenry: FFT-Accelerated Inductance Extraction for Voxelized Geometries

    KAUST Repository

    Yucel, Abdulkadir C.; Georgakis, Ioannis P.; Polimeridis, Athanasios G.; Bagci, Hakan; White, Jacob K.

    2018-01-01

    inductance extractor, FastHenry. Just like FastHenry, VoxHenry solves a combination of the electric volume integral equation and the current continuity equation, but with three distinctions that make VoxHenry suitable and extremely efficient for analyzing

  2. NOAA Ship Henry B. Bigelow Underway Meteorological Data, Quality Controlled

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NOAA Ship Henry B. Bigelow Underway Meteorological Data (delayed ~10 days for quality control) are from the Shipboard Automated Meteorological and Oceanographic...

  3. Comparison of the acute effects of Tulbaghia violacea William Henry ...

    African Journals Online (AJOL)

    William Henry Harvey (Alliaceae) on blood pressure and heart rate of ... (WKY), and compare the results obtained with those for adult spontaneously hypertensive rats (SHR). Methods: T. ... have similar secondary metabolites and biological ...

  4. Henri Poincaré: Death centenary (1854-1912)

    Science.gov (United States)

    Heinzmann, Gerhard; Villani, Cédric

    2014-08-01

    The year 2012 marked the centenary of the death of Henri Poincaré (Nancy, 1854-Paris, 1912), and through the agency of the Henri-Poincaré Institute in Paris, the Henri-Poincaré Archives in Nancy and The London Mathematical Society, brought with it several exhibitions and meetings commemorating one of the greatest minds in contemporary times. Often referred to as the last polymath, Poincaré embraced multiple branches of mathematics, theoretical physics and celestial mechanics, and made significant contributions to philosophy of science (Heinzmann & Stump, Henri Poincaré, 2013). He wrote 25 textbooks and monographs, 500-plus articles, and was deeply involved in the organization and administration of science at both the national and international levels.1

  5. L'Abbe Henri Breuil: Archaeologist

    Directory of Open Access Journals (Sweden)

    Lawrence Guy Straus

    1992-05-01

    Full Text Available In his otherwise excellent book, A History of Archaeological Thought, Trigger (1989: 156 makes only one passing reference in a half-sentence to the central figure in the development of Paleolithic prehistory in the first half of the 20th century -- and manages to get his name wrong, confusing Henri Breuil with his long-time, close colleague, Hugo Obenrnaie . Thirty years after his death, Breuil's role in the history of Old World prehistory required more serious consideration. He was a seminal figure not only in rock art studies, but also in the archaeology of at least France, Spain, England, Portugal, South Africa, and China. Before I had read Trigger's work or Sackett's (1991 critique of my supposed misinterpretation of Breuil's theoretical stance (e.g., Straus 1986, 1987, I had presented a review of Breuil's contributions in the 1991 Annual Snead-Wertheim Lecture in Anthropology and History at the University of New Mexico (Straus n.d.. The following is a brief summary of some of my conclusions.

  6. Henry Head and the Theatre of Reverie

    Directory of Open Access Journals (Sweden)

    Tiffany Watt-Smith

    2011-04-01

    Full Text Available In 1903, the neurologist Henry Head (1861-1940 embarked on a painful self-experiment, in which he severed the radial nerve of his left arm, and then charted the gradual and faltering return of sensitivity to the limb over the next four and a half years. To directly experience his own sensations, Head entered into a trance-like state of distraction or reverie he called a ‘negative attitude of attention’. This article explores Head’s peculiar technique for looking within, and argues that while introspection was an established strategy in psychological laboratories, Head’s reverie also resonated with techniques associated with actors and theatrical audiences during this period. Viewing psychological self-experimentation through the lens of theatre, this article makes visible aspects of Head’s embodied, affective laboratory encounters, often obscured in accounts of his experiment. At the same time, it proposes that the broader historical and cultural significance of Head’s experiment lies in his attempt to observe himself by producing states of inattention and reverie at will, mental ‘attitudes’ that were themselves the subject of a rapidly evolving debate in scientific and aesthetic circles at the turn of the twentieth century.

  7. Victor Henri: 111 years of his equation.

    Science.gov (United States)

    Cornish-Bowden, Athel; Mazat, Jean-Pierre; Nicolas, Serge

    2014-12-01

    Victor Henri's great contribution to the understanding of enzyme kinetics and mechanism is not always given the credit that it deserves. In addition, his earlier work in experimental psychology is totally unknown to biochemists, and his later work in spectroscopy and photobiology almost equally so. Applying great rigour to his analysis he succeeded in obtaining a model of enzyme action that explained all of the observations available to him, and he showed why the considerable amount of work done in the preceding decade had not led to understanding. His view was that only physical chemistry could explain the behaviour of enzymes, and that models should be judged in accordance with their capacity not only to explain previously known facts but also to predict new observations against which they could be tested. The kinetic equation usually attributed to Michaelis and Menten was in reality due to him. His thesis of 1903 is now available in English. Copyright © 2014 Elsevier B.V. and Société française de biochimie et biologie Moléculaire (SFBBM). All rights reserved.

  8. Measurement of the B$_{d}^{0}$ meson oscillation frequency

    CERN Document Server

    Acciarri, M; Aguilar-Benítez, M; Ahlen, S P; Alpat, B; Alcaraz, J; Alemanni, G; Allaby, James V; Aloisio, A; Alverson, G; Alviggi, M G; Ambrosi, G; Anderhub, H; Andreev, V P; Angelescu, T; Antreasyan, D; Arefev, A; Azemoon, T; Aziz, T; Bagnaia, P; Baksay, L; Ball, R C; Banerjee, S; Banicz, K; Barillère, R; Barone, L; Bartalini, P; Baschirotto, A; Basile, M; Battiston, R; Bay, A; Becattini, F; Becker, U; Behner, F; Berdugo, J; Berges, P; Bertucci, B; Betev, B L; Biasini, M; Biland, A; Bilei, G M; Blaising, J J; Blyth, S C; Bobbink, Gerjan J; Böck, R K; Böhm, A; Borgia, B; Boucham, A; Bourilkov, D; Bourquin, Maurice; Boutigny, D; Brambilla, Elena; Branson, J G; Brigljevic, V; Brock, I C; Buijs, A; Burger, J D; Burger, W J; Busenitz, J K; Buytenhuijs, A O; Cai, X D; Campanelli, M; Capell, M; Cara Romeo, G; Caria, M; Carlino, G; Cartacci, A M; Casaus, J; Castellini, G; Castello, R; Cavallari, F; Cavallo, N; Cecchi, C; Cerrada-Canales, M; Cesaroni, F; Chamizo-Llatas, M; Chan, A; Chang, Y H; Chaturvedi, U K; Chemarin, M; Chen, A; Chen, G; Chen, G M; Chen, H F; Chen, H S; Chen, M; Chiefari, G; Chien, C Y; Choi, M T; Cifarelli, Luisa; Cindolo, F; Civinini, C; Clare, I; Clare, R; Cohn, H O; Coignet, G; Colijn, A P; Colino, N; Costantini, S; Cotorobai, F; de la Cruz, B; Csilling, Akos; Dai, T S; D'Alessandro, R; De Asmundis, R; De Boeck, H; Degré, A; Deiters, K; Denes, P; De Notaristefani, F; DiBitonto, Daryl; Diemoz, M; Van Dierendonck, D N; Di Lodovico, F; Dionisi, C; Dittmar, Michael; Dominguez, A; Doria, A; Dorne, I; Dova, M T; Drago, E; Duchesneau, D; Duinker, P; Durán, I; Dutta, S; Easo, S; Efremenko, Yu V; El-Mamouni, H; Engler, A; Eppling, F J; Erné, F C; Ernenwein, J P; Extermann, Pierre; Fabre, M; Faccini, R; Falciano, S; Favara, A; Fay, J; Fedin, O; Felcini, Marta; Ferguson, T; Fernández, D; Ferroni, F; Fesefeldt, H S; Fiandrini, E; Field, J H; Filthaut, Frank; Fisher, P H; Forconi, G; Fredj, L; Freudenreich, Klaus; Furetta, C; Galaktionov, Yu; Ganguli, S N; Gau, S S; Gentile, S; Gerald, J; Gheordanescu, N; Giagu, S; Goldfarb, S; Goldstein, J; Gong, Z F; Gougas, Andreas; Gratta, Giorgio; Grünewald, M W; Gupta, V K; Gurtu, A; Gutay, L J; Hangarter, K; Hartmann, B; Hasan, A; Hebbeker, T; Hervé, A; Van Hoek, W C; Hofer, H; Hoorani, H; Hou, S R; Hu, G; Ilyas, M M; Innocente, Vincenzo; Janssen, H; Jin, B N; Jones, L W; de Jong, P; Josa-Mutuberria, I; Kasser, A; Khan, R A; Kamyshkov, Yu A; Kapinos, P; Kapustinsky, J S; Karyotakis, Yu; Kaur, M; Kienzle-Focacci, M N; Kim, D; Kim, J K; Kim, S C; Kim, Y G; Kinnison, W W; Kirkby, A; Kirkby, D; Kirkby, Jasper; Kiss, D; Kittel, E W; Klimentov, A; König, A C; Korolko, I; Koutsenko, V F; Krämer, R W; Kramer, T; Krenz, W; Kuijten, H; Kunin, A; Ladrón de Guevara, P; Landi, G; Lapoint, C; Lassila-Perini, K M; Laurikainen, P; Lebeau, M; Lebedev, A; Lebrun, P; Lecomte, P; Lecoq, P; Le Coultre, P; Lee Jae Sik; Lee, K Y; Leggett, C; Le Goff, J M; Leiste, R; Lenti, M; Leonardi, E; Levchenko, P M; Li Chuan; Lieb, E H; Lin, W T; Linde, Frank L; Lista, L; Liu, Z A; Lohmann, W; Longo, E; Lu, W; Lü, Y S; Lübelsmeyer, K; Luci, C; Luckey, D; Ludovici, L; Luminari, L; Lustermann, W; Ma Wen Gan; Macchiolo, A; Maity, M; Majumder, G; Malgeri, L; Malinin, A; Maña, C; Mangla, S; Marchesini, P A; Marin, A; Martin, J P; Marzano, F; Massaro, G G G; Mazumdar, K; McNally, D; Mele, S; Merola, L; Meschini, M; Metzger, W J; Von der Mey, M; Mi, Y; Mihul, A; Van Mil, A J W; Mirabelli, G; Mnich, J; Monteleoni, B; Moore, R; Morganti, S; Mount, R; Müller, S; Muheim, F; Nagy, E; Nahn, S; Napolitano, M; Nessi-Tedaldi, F; Newman, H; Nippe, A; Nowak, H; Organtini, G; Ostonen, R; Pandoulas, D; Paoletti, S; Paolucci, P; Park, H K; Pascale, G; Passaleva, G; Patricelli, S; Paul, T; Pauluzzi, M; Paus, C; Pauss, Felicitas; Peach, D; Pei, Y J; Pensotti, S; Perret-Gallix, D; Petrak, S; Pevsner, A; Piccolo, D; Pieri, M; Pinto, J C; Piroué, P A; Pistolesi, E; Plyaskin, V; Pohl, M; Pozhidaev, V; Postema, H; Produit, N; Prokofev, D; Prokofiev, D O; Raghavan, R; Rahal-Callot, G; Rancoita, P G; Rattaggi, M; Raven, G; Razis, P A; Read, K; Ren, D; Rescigno, M; Reucroft, S; Van Rhee, T; Riemann, S; Riemers, B C; Riles, K; Rind, O; Ro, S; Robohm, A; Rodin, J; Rodríguez-Calonge, F J; Roe, B P; Röhner, S; Romero, L; Rosier-Lees, S; Rosselet, P; Van Rossum, W; Roth, S; Rubio, Juan Antonio; Rykaczewski, H; Salicio, J; Sánchez, E; Santocchia, A; Sarakinos, M E; Sarkar, S; Sassowsky, M; Sauvage, G; Schäfer, C; Shchegelskii, V; Schmidt-Kärst, S; Schmitz, D; Schmitz, P; Schneegans, M; Schöneich, B; Scholz, N; Schopper, Herwig Franz; Schotanus, D J; Schwenke, J; Schwering, G; Sciacca, C; Sciarrino, D; Sens, Johannes C; Servoli, L; Shevchenko, S; Shivarov, N; Shoutko, V; Shukla, J; Shumilov, E; Shvorob, A V; Siedenburg, T; Son, D; Sopczak, André; Soulimov, V; Smith, B; Spillantini, P; Steuer, M; Stickland, D P; Sticozzi, F; Stone, H; Stoyanov, B; Strässner, A; Strauch, K; Sudhakar, K; Sultanov, G G; Sun, L Z; Susinno, G F; Suter, H; Swain, J D; Tang, X W; Tauscher, Ludwig; Taylor, L; Ting, Samuel C C; Ting, S M; Tonisch, F; Tonutti, M; Tonwar, S C; Tóth, J; Tully, C; Tuchscherer, H; Tung, K L; Ulbricht, J; Uwer, U; Valente, E; Van de Walle, R T; Vesztergombi, G; Vetlitskii, I; Viertel, Gert M; Vivargent, M; Völkert, R; Vogel, H; Vogt, H; Vorobev, I; Vorobyov, A A; Vorvolakos, A; Wadhwa, M; Wallraff, W; Wang, J C; Wang, X L; Wang, Y F; Wang, Z M; Weber, A; Wittgenstein, F; Wu, S X; Wynhoff, S; Xu, J; Xu, Z Z; Yang, B Z; Yang, C G; Yao, X Y; Ye, J B; Yeh, S C; You, J M; Zalite, A; Zalite, Yu; Zemp, P; Zeng, Y; Zhang, Z; Zhang, Z P; Zhou, B; Zhou, Y; Zhu, G Y; Zhu, R Y; Zichichi, Antonino

    1996-01-01

    Time-dependent \\Bd-\\Bbd\\ mixing is studied using 1.5 million hadronic Z decays collected by L3. Semileptonic B decays are selected by requiring at least one reconstructed lepton in both thrust hemispheres. Charge correlations between the tagged leptons are studied as a function of proper time. The proper time of the b-hadron decay is measured by reconstructing the production and decay vertices using a silicon microvertex detector. The measured \\Bd\\ meson oscillation frequency corresponds to a mass difference \\Dmd\\ between the two \\Bd\\ mass eigenstates of \\begin{displaymath} \\Dmd = \\left( 0.496 ^{+ 0.055}_{- 0.051}\\ \\mathrm{(stat)} \\pm{ 0.043}\\ \\mathrm{(syst)} \\right)\\ \\mathrm{ps}^{-1}. \\end{displaymath}

  9. Saudi production capacity climbing to 10 million b/d

    International Nuclear Information System (INIS)

    Anon.

    1994-01-01

    Saudi Arabia this year is completing its expansion of production capacity and developing recent discoveries to enhance export flexibility. The 3 million b/d capacity expansion to 10 million b/d, announced in 1989, is on target for completion by year end 1994. Most of the effort involves restoration of mothballed production equipment and installation of several gas-oil separation plants (GOSPs) in existing fields. But Saudi Arabian Oil Co. (Saudi Aramco) also this year will start up production of extra-light oil from a new field in the central part of the kingdom. Start-up of Hawtah area production demonstrates success of an oil search Aramco began after receiving exclusive exploration rights to nearly all of Saudi Arabia's prospective area in 1986. From new fields and traditional producing areas, therefore, Saudi Arabia has the potential to expand production capacity beyond 10 million b/d. The paper describes the development of the extra capacity

  10. “Not a man from England”: assimilating the exotic ‘other’ through performance, from Henry IV to Henry VI

    OpenAIRE

    Penlington, A.

    2010-01-01

    This essay will consider recent shifts in performance representations of England and the exotic ‘other’ in Shakespeare’s Henry IV, Henry V and Henry VI plays. By tracing the texts’ varied representations of non-English Britons and those for whom English is not their mother tongue (such as Owen Glyndwr in 1 Henry IV and Princess Catherine in Henry V), recent criticism has identified that Shakespeare’s narrative portrays the challenges of assimilating ‘otherness’ within English culture. This es...

  11. Construction of Eukaryotic Expression Vector with mBD1-mBD3 Fusion Genes and Exploring Its Activity against Influenza A Virus

    Directory of Open Access Journals (Sweden)

    Wanyi Li

    2014-03-01

    Full Text Available Influenza (flu pandemics have exhibited a great threat to human health throughout history. With the emergence of drug-resistant strains of influenza A virus (IAV, it is necessary to look for new agents for treatment and transmission prevention of the flu. Defensins are small (2–6 kDa cationic peptides known for their broad-spectrum antimicrobial activity. Beta-defensins (β-defensins are mainly produced by barrier epithelial cells and play an important role in attacking microbe invasion by epithelium. In this study, we focused on the anti-influenza A virus activity of mouse β-defensin 1 (mBD1 and β defensin-3 (mBD3 by synthesizing their fusion peptide with standard recombinant methods. The eukaryotic expression vectors pcDNA3.1(+/mBD1-mBD3 were constructed successfully by overlap-PCR and transfected into Madin-Darby canine kidney (MDCK cells. The MDCK cells transfected by pcDNA3.1(+/mBD1-mBD3 were obtained by G418 screening, and the mBD1-mBD3 stable expression pattern was confirmed in MDCK cells by RT-PCR and immunofluorescence assay. The acquired stable transfected MDCK cells were infected with IAV (A/PR/8/34, H1N1, 0.1 MOI subsequently and the virus titers in cell culture supernatants were analyzed by TCID50 72 h later. The TCID50 titer of the experimental group was clearly lower than that of the control group (p < 0.001. Furthermore, BALB/C mice were injected with liposome-encapsulated pcDNA3.1(+/mBD1-mBD3 through muscle and then challenged with the A/PR/8/34 virus. Results showed the survival rate of 100% and lung index inhibitory rate of 32.6% in pcDNA3.1(+/mBD1-mBD3group; the TCID50 titer of lung homogenates was clearly lower than that of the control group (p < 0.001. This study demonstrates that mBD1-mBD3 expressed by the recombinant plasmid pcDNA3.1(+/mBD1-mBD3 could inhibit influenza A virus replication both in vitro and in vivo. These observations suggested that the recombinant mBD1-mBD3 might be developed into an agent for

  12. Lise: a recoil spectrometer at GANIL for the production and study of secondary radioactive beams. Present status and future

    International Nuclear Information System (INIS)

    Mueller, A.C.

    1989-01-01

    The doubly achromatic spectrometer LISE, installed at the intermediate-energy heavy-ion facility GANIL is now operating since five years. Essentially, it is composed by two dipole-magnets selecting (in A/Z) and refocusing (achromatically) the projectile-like radioactive fragment-beams emitted at 0 0 . We shall review some of the essential properties of LISE. Some selected examples will be used to demonstrate experimental results which have been obtained so far (discovery of numerous new nuclei up to the drip-lines, half-life measurements, β-γ and delayed-particle spectroscopy, spin-aligned beams, total reaction cross-sections). We shall also discuss several improvements, in particular a cross-field electrostatic/electromagnetic post separator, which are expected to provide in the near future secondary beams of still increased intensity and isotopic purity

  13. SOA-BD: Service Oriented Architecture for Biomedical Devices

    Directory of Open Access Journals (Sweden)

    João Marcos Teixeira Lacerda

    2017-05-01

    Full Text Available Introduction: The communication of information systems with biomedical devices has become complex not only due to the existence of several private communication protocols, but also to the immutable way that software is embedded into these devices. In this sense, this paper proposes a service-oriented architecture to access biomedical devices as a way to abstract the mechanisms of writing and reading data from these devices, thus contributing to enable the focus of the development team of biomedical software to be intended for its functional requirements, i.e. business rules relevant to the problem domain. Methods The SOA-BD architecture consists of five main components: A Web Service for transport and conversion of the device data, Communication Protocols to access the devices, Data Parsers to preprocess data, a Device Repository to store data and transmitted information and Error handling, for error handling of these information. For the development of SOA-BD, technologies such as the XML language and the Java programming language were used. Besides, Software Engineering concepts such as Design Patterns were also used. For the validation of this work, data has been collected from vital sign monitors in an Intensive Care Unit using HL7 standards. Results The tests obtained a difference of about only 1 second in terms of response time with the use of SOA-BD. Conclusion SOA-BD achieves important results such as the reduction on the access protocol complexity, the opportunity for treating patients over long distances, allowing easier development of monitoring applications and interoperability with biomedical devices from diverse manufacturers.

  14. Trajectory and physical properties of near-Earth asteroid 2009 BD

    NARCIS (Netherlands)

    Farnocchia, D.; Mommert, M.; Hora, J. L.; Chesley, S. R.; Vokrouhlický, D.; Trilling, D. E.; Mueller, M.; Harris, A. W.; Smith, H. A.; Fazio, G. G.; Knežević, Zoran; Lemaitre, Anne

    2014-01-01

    We analyze the trajectory of near-Earth asteroid 2009~BD, which is a candidate target of the NASA Asteroid Redirect Mission. The small size of 2009 BD and its Earth-like orbit pose challenges to understanding the dynamical properties of 2009 BD. In particular, nongravitational perturbations, such as

  15. LA BD EN CLASSE DE FLE ? POURQUOI PAS !

    Directory of Open Access Journals (Sweden)

    Ana-Marina Tomescu

    2009-11-01

    Full Text Available Dans la présente étude nous allons essayer de démontrer que la BD représente certainement un phénomène de civilisation, qui donne la possibilité aux apprenants d’une langue étrangère de mieux comprendre un comportement culturel spécifique. Elle aide les apprenants à améliorer leur compétence socio-culturelle, parce qu’elle fait ressortir des éléments de civilisation pertinents, des clichés fréquemment rencontrés dans le monde francophone. La langue utilisée dans les BD est le français de tous les jours, l’accent est mis sur la conversation dans les plus diverses situations et à l’aide des registres de langue différents. Ce sont des motifs suffisants qui recommandent l’utilisation de la BD en classe de FLE, sans oublier de mentionner un atout essentiel : l’humour.

  16. In praise of the literary eponym--Henry V sign.

    LENUS (Irish Health Repository)

    Shanahan, F

    2013-01-01

    The use of eponyms in medicine is often discouraged. However, the literary eponym should be an exception as it is not linked with many of the difficulties associated with conventional eponyms and offers descriptive brevity and accuracy. Here, we illustrate the point with Henry V sign, which will be familiar to many who have cared for patients in the terminal stage of illness.

  17. Henry the Seventh and Italy, an historiographical account

    Directory of Open Access Journals (Sweden)

    Gian Maria Varanini

    2014-06-01

    Full Text Available The article represents an introduction to the contributions published in the monographic section dedicated to the expedition of Henry VII of Luxembourg in Italy (1310-1313. It provides an historiographic overview and some insightful clues.

  18. The Transformative Intellectual: An Examination of Henry Giroux's Ethics

    Science.gov (United States)

    Kashani, Tony

    2012-01-01

    This article explores Henry Giroux's contributions to critical pedagogy. The author demonstrates how Giroux, as a public intellectual, has found his Ethics in the right place. The author further argues that Giroux's Ethics of virtue are present not only in the public person but also in his transformative writing.

  19. Kesknoored tegid visiidi Šveitsi / Henri Kaselo

    Index Scriptorium Estoniae

    Kaselo, Henri

    2005-01-01

    Keskerakonna noorte esindus külastas 20.-25. aprillini 2005 Šveitsi, et osaleda sealsete noorte liberaalide Jungfreisinnige Schweizi kongressil. Delegatsiooni kuulusid esimees Tarmo Lausing, välissekretär Olga Sõtnik, endine pressisekretär Raimond Kaljulaid ja noortekogu esimees Henri Kaselo

  20. The Teaching Approach of Henry Schaefer-Simmern.

    Science.gov (United States)

    Abrahamson, Roy E.

    1980-01-01

    This description of the teaching approach of Henry Schaefer-Simmern emphasizes his use of questioning to evoke student self-evaluation and to develop clarity of vision and interfunctional unity in students' art products and their mental, artistic conceiving. Two case reports of his work with elementary students are included. (Author/SJL)

  1. Principles in Action: The Work of Henri Wallon

    Science.gov (United States)

    Voyat, Gilbert

    1974-01-01

    An examination of the life and philosophy of Henri Wallon, A French psychiatrist, psychologist, and educator, focusing on his views regarding the role of imitation in adaptation and learning, emotional development, syncretic thought, his differences with Piaget, and an assessment of the impact of his work. (EH)

  2. La Vie et L'oeuvre d'Henri Wallon.

    Science.gov (United States)

    Aubrey, Carol

    1987-01-01

    Outlines the life and philosophy of noted French child psychologist, Henri Wallon (1879-1962). Reviews the philosophical origins of the Wallonian Approach including the theory of emotions, the development of representational thought, the role of imitation in the formation of representation, and the role of language in the development of thought…

  3. The Failed Educations of John Stuart Mill and Henry Adams.

    Science.gov (United States)

    Crossley, Robert

    1979-01-01

    Analyzes and contrasts Mill's "Autobiography" and Adams'"The Education of Henry Adams" in order to present two approaches to the nature of education and of failure. Maintains that their perspectives may serve as catalysts and cautions for contemporary theories of education and its utility and relevance. (CAM)

  4. Henri Becquerel and the discovery of natural radioactivity

    International Nuclear Information System (INIS)

    Barquins, M.

    2003-01-01

    This article presents the life and achievements of Henri Becquerel particularly in the domain of natural radioactivity which he discovered. In 1903 H.Becquerel was awarded the Nobel prize of physics (jointly with the Curies). The author highlights the importance of his talent but also the influence of his family background: his grand-father and father were both renowned scientists

  5. Henri Poincaré a biography through the daily papers

    CERN Document Server

    Ginoux, Jean-Marc

    2014-01-01

    On July 17, 2012, the centenary of Henri Poincaré's death was commemorated; his name being associated with so many fields of knowledge that he was considered as the Last Universalist. In Pure and Applied Mathematics, Physics, Astronomy, Engineering and Philosophy, his works have had a great impact all over the world. Poincaré acquired in his lifetime such a reputation that, both nationally and internationally, his life and career were made the object of various articles in the daily papers not only in France, but also in the USA. Some of his philosophical concepts have even caused sharp controversies in the Press (as we will discover in this book).This work presents an original portrait of Henri Poincaré based on various press cuttings from The New York Times, The San Francisco Sunday Call, The Times, The Sun, The Washington Post that chronicled unknown anecdotes of his life (for example, his first name was actually not Henri, but Henry; he obtained his high school diploma in sciences with a zero in mathem...

  6. 2. Robin Attfield Henry Odera Oruka, Ecophilosophy and Climate ...

    African Journals Online (AJOL)

    Attfield

    Henry Odera Oruka, ecophilosophy, climate change ethics, impacts of climate ... One of the fields of environmental philosophy which he would almost ... engineering, and on “Humanity's Carbon Budget”, followed by Conclusions about ... countries that are largely responsible for these emissions must take the lion's share of.

  7. Comparison of the acute effects of Tulbaghia violacea William Henry ...

    African Journals Online (AJOL)

    Purpose: To assess the effect of the crude methanol leaf extracts of Tulbaghia violacea William Henry Harvey (Alliaceae) on blood pressure (BP) and heart rate in ageing normotensive Wistar Kyoto rats (WKY), and compare the results obtained with those for adult spontaneously hypertensive rats (SHR). Methods: T.

  8. Potential Beneficial Effects of Tulbaghia violacea William Henry ...

    African Journals Online (AJOL)

    Tulbaghia violacea William Henry Harvey (Harv. Alliaceae) is a small bulbous herb belonging to the family Alliaceae. It is used in South Africa to treat fever, colds, asthma, paralysis, and hypertension. Meanwhile, cardiovascular disease accounts for about 30 % of total global death, with most of these deaths occurring in low ...

  9. Thomas Henry Huxley et la Bible Thomas Henry Huxley and the Bible

    Directory of Open Access Journals (Sweden)

    Christophe Duvey

    2009-10-01

    Full Text Available Thomas Henry Huxley devoted several essays to the study of the Bible. This interest can only be accounted for if his ideas on history, religion as well as epistemology are examined. According to him, a struggle between free thought and supernaturalism was culminating during the Victorian era, hence the need for a “New Reformation” which was heir to the ideals of freedom defended by the humanists of the Renaissance. This movement opposed the principles of the supporters of what he called “ecclesiasticism”. The advocates of the “New Reformation” could rely on the progress of modern science, and agnosticism, which Huxley identified with scientific method, became its epistemological foundation. As a result, Huxley thought that the authority of physical science was in conflict with the infallibility of the Scriptures and with the theological arguments which rested on it, and this notably led him to the conclusion that the biblical narrative of the Flood was unhistorical. The naturalisation of the Scriptures seems then logically to follow his philosophical views based on the limits of human knowledge.It appears that it was the question of authority which underlay Huxley’s interest in the Bible. He thought that the authority of the Scriptures must be replaced by that of science.

  10. Obituary: Roy Henry Garstang (1925-2009)

    Science.gov (United States)

    Malville, J.

    2011-12-01

    Roy Henry Garstang 84 passed away on November 1, 2009 in Boulder Colorado. He was born in Southport, England in September of 1925 to Percy Brocklehurst and Eunice (Gledhill) Garstang. He won a scholarship to Caius College in Cambridge University. Because it was wartime, he could spend only two years at his studies. However, he managed to complete three years of required work during that time, and then spent 1945-46 as a Junior Scientific Officer at the Royal Aircraft Establishment at Farnborough. He received his BA in 1946 from Cambridge, his MA in 1950, and his PhD in Mathematics in 1954, with a thesis: "Atomic Transitions in Astrophysics," working under D. R. Hartree. He also received a ScD from Cambridge in Physics and Chemistry in 1983. He married Ann in August 1959. She and two daughters, Jennifer and Susan, survive him. While still pursuing his PhD, Roy Garstang served as a Research Associate at the Yerkes Observatory, from 1951-1952, working under Subrahmanyan Chandrasekhar. During that time he continued with his own calculations of atomic structure and transition probabilities, although these were not part of Chandra's research interests. After earning his PhD, he went to teach at the University of London, where he also served as the Assistant Director of the University of London Observatory (1959-1964). He was editor of "The Observatory" Magazine form 1953-1960. The continuing theme of this research was to help meet the needs of astrophysicists for atomic data. In 1964, he left England for the United States, where he joined the faculty at the University of Colorado, Boulder, where he would remain for the rest of his professional career. It was entirely fitting, considering his interest in performing calculations of interest to astrophysicists, that soon after arriving in Boulder he was appointed Chairman of JILA - Joint Institute for Laboratory Astrophysics (1966-1967). He was Director of the Division of Physics and AstroGeophysics (1979-80), acting

  11. Study and development of a GANIL beam intensity measurement system with high resolution (<1 nA) and with high accuracy (<1%)

    International Nuclear Information System (INIS)

    Etaix, Geoffroy

    1999-01-01

    The GANIL beam intensity measurement System enables tuning and control of the accelerator system. All along the ion beam transport line, the intensity is measured continuously with low frequency current transformers. The performance as optimized today is not satisfactory to precisely determine the accelerator efficiency on-line. A first study showed that the only sensors usable at GANIL are sensors sensitive to magnetic field (current transformers) and to electric field (capacitive probes). The theoretical study searched to predict the output of these types of sensors and enabled to define a signal treatment which corresponds to the specifications. For every sensor, this calculation is validated experimentally. Moreover this study raised the problem of calibration. The different tests completed allowed a definition of the real characteristics of the current measurements and a choice of the appropriate system. (author) [fr

  12. High Production of 2,3-Butanediol (2,3-BD by Raoultella ornithinolytica B6 via Optimizing Fermentation Conditions and Overexpressing 2,3-BD Synthesis Genes.

    Directory of Open Access Journals (Sweden)

    Taeyeon Kim

    Full Text Available Biological production of 2,3-butandiol (2,3-BD has received great attention as an alternative to the petroleum-based 2,3-BD production. In this study, a high production of 2,3-BD in fed-batch fermentation was investigated with a newly isolated bacterium designated as Raoultella ornithinolytica B6. The isolate produced 2,3-BD as the main product using hexoses (glucose, galactose, and fructose, pentose (xylose and disaccharide (sucrose. The effects of temperature, pH-control schemes, and agitation speeds on 2,3-BD production were explored to optimize the fermentation conditions. Notably, cell growth and 2,3-BD production by R. ornithinolytica B6 were higher at 25°C than at 30°C. When three pH control schemes (no pH control, pH control at 7, and pH control at 5.5 after the pH was decreased to 5.5 during fermentation were tested, the best 2,3-BD titer and productivity along with reduced by-product formation were achieved with pH control at 5.5. Among different agitation speeds (300, 400, and 500 rpm, the optimum agitation speed was 400 rpm with 2,3-BD titer of 68.27 g/L, but acetic acid was accumulated up to 23.32 g/L. Further enhancement of the 2,3-BD titer (112.19 g/L, yield (0.38 g/g, and productivity (1.35 g/L/h as well as a significant reduction of acetic acid accumulation (9.71 g/L was achieved by the overexpression of homologous budABC genes, the 2,3-BD-synthesis genes involved in the conversion of pyruvate to 2,3-BD. This is the first report presenting a high 2,3-BD production by R.ornithinolytica which has attracted little attention with respect to 2,3-BD production, extending the microbial spectrum of 2,3-BD producers.

  13. Characterization of Phosphate Transporters BdPT4 and BdPT8 in Mycorrhizal and Non-Mychorrhizal Brachypodium distachyon

    DEFF Research Database (Denmark)

    Clausen, Signe Sandbech

    PT proteins were expressed in cells where direct PTs are believed to perform their function, as well as in the vascular tissue. In NM plants, BdPT4 was localized to the plasma membrane whereas BdPT8 accumulated in the endoplasmic reticulum (ER) in the secretory pathway. A similar expression pattern...... was observed in non-arbusculated cells of AM plants. In arbusculated cells, BdPT8 was detected in the ER while BdPT4 was localized to the plasma membrane and the periarbuscular membrane (PAM) surrounding the arbuscular trunk and thick branches, which further supported a role of both BdPTs in direct Pi uptake......Phosphorus (P) is an essential plant nutrient in agricultural production but the P rock reserves used for production of fertilizers are currently being depleted. One approach to reduce the demand on P fertilizers is to optimize the phosphate (Pi) uptake and utilization efficiency of crop plants...

  14. Utilization of plant-derived recombinant human β-defensins (hBD-1 and hBD-2) for averting salmonellosis.

    Science.gov (United States)

    Patro, Sunita; Maiti, Soumitra; Panda, Santosh Kumar; Dey, Nrisingha

    2015-04-01

    We describe the use of plant-made β-defensins as effective antimicrobial substances for controlling salmonellosis, a deadly infection caused by Salmonella typhimurium (referred to further as S. typhi). Human β-defensin-1 (hBD-1) and -2 (hBD-2) were expressed under the control of strong constitutive promoters in tobacco plants, and bio-active β-defensins were successfully extracted. In the in vitro studies, enriched recombinant plant-derived human β-defensin-1 (phBD-1) and -2 (phBD-2) obtained from both T1 and T2 transgenic plants showed significant antimicrobial activity against Escherichia coli and S. typhi when used individually and in various combinations. The 2:1 peptide combination of phBD-1:phBD-2 with peptides isolated from T1-and T2-generation plants reduced the growth of S. typhi by 96 and 85 %, respectively. In vivo studies employing the mouse model (Balb/c) of Salmonella infection clearly demonstrated that the administration of plant-derived defensins individually and in different combinations enhanced the mean survival time of Salmonella-infected animals. When treatment consisted of the 2:1 phBD-1:phBD-2 combination, approximately 50 % of the infected mice were still alive at 206 h post-inoculation; the lowest number of viable S. typhi was observed in the liver and spleen of infected animals. We conclude that plant-made recombinant β-defensins (phBD-1 and phBD-2) are promising antimicrobial substances and have the potential to become additional tools against salmonellosis, particularly when used in combination.

  15. INOVATION AND ANTREPRENEURIAL CREATIVITY BUSINESS DURING HENRY FORD

    Directory of Open Access Journals (Sweden)

    GHICAJANU MIHAELA

    2015-03-01

    Full Text Available In this paper I presented the innovation and entrepeneurial creativity as a basis in the process of business redesign. I chose as a case study the the Ford brand products, because it is considered that Henry Ford is one of the greatest innovators and entrepreneurs of all time and I decided to present and to analyze these things. The first part of the paper will include theoretical approaches on the innovation and creativity business concepts and premises, and then I showed the ways in which four types of economic innovation under the leadership of Henry Ford (innovation in product, in process, market and organizational were achieved, with the purpose to recognize them in other companies, nowadays .

  16. Iraagi olukorral on poliitiline lahendus / Henry A. Kissinger

    Index Scriptorium Estoniae

    Kissinger, Henry, 1923-

    2007-01-01

    USA endine riigisekretär Henry Kissinger kirjutab, et Ameerika Ühendriikide eesmärgiks peaks olema riikidevaheline kokkulepe, mis tunnistaks Iraagi rahvusvahelist staatust. See oleks vägivalla lõpetamiseks hea alus ja eeltingimuseks vägede väljaviimisele. Vt. samas: Ameerika Ühendriikide vahekokkuvõte Iraagi sõja kohta oli suhteliselt pessimistlik

  17. An investigation of Bd0 and Bs0 oscillation

    Science.gov (United States)

    Buskulic, D.; de Bonis, I.; Decamp, D.; Ghez, P.; Goy, C.; Lees, J.-P.; Minard, M.-N.; Odier, P.; Pietrzyk, B.; Ariztizabal, F.; Comas, P.; Crespo, J. M.; Efthymiopoulos, I.; Fernandez, E.; Fernandez-Bosman, M.; Gaitan, V.; Garrido, Ll.; Martinez, M.; Mattison, T.; Orteu, S.; Pacheco, A.; Padilla, C.; Pascual, A.; Creanza, D.; de Palma, M.; Farilla, A.; Iaselli, G.; Maggi, G.; Marinelli, N.; Natali, S.; Nuzzo, S.; Ranieri, A.; Raso, G.; Romano, F.; Ruggieri, F.; Selvaggi, G.; Silvestris, L.; Tempesta, P.; Zito, G.; Chai, Y.; Hu, H.; Huang, D.; Huang, X.; Lin, J.; Wang, T.; Xie, Y.; Xu, D.; Xu, R.; Zhang, J.; Zhang, L.; Zhao, W.; Bonvicini, G.; Boudreau, J.; Casper, D.; Drevermann, H.; Forty, R. W.; Ganis, G.; Gay, C.; Girone, M.; Hagelberg, R.; Harvey, J.; Hilgart, J.; Jacobsen, R.; Jost, B.; Knobloch, J.; Lehraus, I.; Maggi, M.; Markou, C.; Mato, P.; Meinhard, H.; Minten, A.; Miquel, R.; Moser, H.-G.; Palazzi, P.; Pater, J. R.; Perlas, J. A.; Perrodo, P.; Pusztaszeri, J.-F.; Ranjard, F.; Rolandi, L.; Rothberg, J.; Ruan, T.; Saich, M.; Schlatter, D.; Schmelling, M.; Sefkow, F.; Tejessy, W.; Tomalin, I. R.; Veenhof, R.; Wachsmuth, H.; Wasserbaech, S.; Wiedenmann, W.; Wildish, T.; Witzeling, W.; Wotschack, J.; Ajaltouni, Z.; Bardadin-Otwinowska, M.; Barres, A.; Boyer, C.; Falvard, A.; Gay, P.; Guicheney, C.; Henrard, P.; Jousset, J.; Michael, B.; Montret, J.-C.; Pallin, D.; Perret, P.; Podlyski, F.; Proriol, J.; Saadi, F.; Fearnley, T.; Hansen, J. B.; Hansen, J. D.; Hansen, J. R.; Hansen, P. H.; Johnson, S. D.; Møllerud, R.; Nilsson, B. S.; Kyriakis, A.; Simopoulou, E.; Siotis, I.; Vayaki, A.; Zachariadou, K.; Badier, J.; Blondel, A.; Bonneaud, G.; Brient, J. C.; Bourdon, P.; Fouque, G.; Passalacqua, L.; Rougé, A.; Rumpf, M.; Tanaka, R.; Verderi, M.; Videau, H.; Candlin, D. J.; Parsons, M. I.; Veitch, E.; Focardi, E.; Moneta, L.; Parrini, G.; Corden, M.; Delfino, M.; Georgipoulos, C.; Jaffe, D. E.; Levinthal, D.; Antonelli, A.; Bencivenni, G.; Bologna, G.; Bossi, F.; Campana, P.; Capon, G.; Cerutti, F.; Chiarella, V.; Felici, G.; Laurelli, P.; Mannocchi, G.; Murtas, F.; Murtas, G. P.; Pepe-Altarelli, M.; Salomone, S.; Colrain, P.; Ten Have, I.; Knowles, I. G.; Lynch, J. G.; Maitland, W.; Morton, W. T.; Raine, C.; Reeves, P.; Scarr, J. M.; Smith, K.; Smith, M. G.; Thompson, A. S.; Thorn, S.; Turnbull, R. M.; Brandl, B.; Braun, O.; Geweniger, C.; Hanke, P.; Hepp, V.; Kluge, E. E.; Maumary, Y.; Putzer, A.; Rensch, B.; Stahl, A.; Tittel, K.; Wunsch, M.; Beuselinck, R.; Binnie, D. M.; Cameron, W.; Cattaneo, M.; Colling, D. J.; Dornan, P. J.; Hassard, J. F.; Lieske, N. M.; Moutoussi, A.; Nash, J.; Patton, S.; Payne, D. G.; Phillips, M. J.; San Martin, G.; Sedgbeer, J. K.; Wright, A. G.; Girtler, P.; Kuhn, D.; Rudolph, G.; Vogl, R.; Bowdery, C. K.; Brodbeck, T. J.; Finch, A. J.; Foster, F.; Hughes, G.; Jackson, D.; Keemer, N. R.; Nuttall, M.; Patel, A.; Sloan, T.; Snow, S. W.; Whelan, E. P.; Galla, A.; Greene, A. M.; Kleinknecht, K.; Raab, J.; Renk, B.; Sander, H.-G.; Schmidt, H.; Walther, S. M.; Wanke, R.; Wolf, B.; Bencheikh, A. M.; Benchouk, C.; Bonissent, A.; Calvet, D.; Carr, J.; Coyle, P.; Diaconu, C.; Drinkard, J.; Etienne, F.; Nicod, D.; Payre, P.; Roos, L.; Rousseau, D.; Schwemling, P.; Talby, M.; Adlung, S.; Assmann, R.; Bauer, C.; Blum, W.; Brown, D.; Cattaneo, P.; Dehning, B.; Dietl, H.; Dydak, F.; Frank, M.; Halley, A. W.; Jakobs, K.; Lauber, J.; Lütjens, G.; Lutz, G.; Männer, W.; Richter, R.; Schröder, J.; Schwarz, A. S.; Settles, R.; Seywerd, H.; Stierlin, U.; Stiegle, U.; St. Denis, R.; Wolf, G.; Alemany, R.; Boucrot, J.; Callot, O.; Cordier, A.; Davier, M.; Duflot, L.; Grivaz, J.-F.; Heusse, Ph.; Janot, P.; Kim, D. W.; Le Diberder, F.; Lefrançois, J.; Lutz, A.-M.; Musolino, G.; Schune, M.-H.; Veillet, J.-J.; Videau, I.; Abbaneo, D.; Bagliesi, G.; Batignani, G.; Bottigli, U.; Bozzi, C.; Calderini, G.; Carpinelli, M.; Ciocci, M. A.; Ciulli, V.; Dell'Orso, R.; Ferrante, I.; Fidecaro, F.; Foà, L.; Forti, F.; Giassi, A.; Giorgi, M. A.; Gregorio, A.; Ligabue, F.; Lusiani, A.; Mannelli, E. B.; Marrocchesi, P. S.; Messineo, A.; Palla, F.; Rizzo, G.; Sanguinetti, G.; Spagnolo, P.; Steinberger, J.; Tenchini, R.; Tonelli, G.; Triggiani, G.; Valassi, A.; Vannini, C.; Venturi, A.; Verdini, P. G.; Walsh, J.; Betteridge, A. P.; Gao, Y.; Green, M. G.; Johnson, D. L.; March, P. V.; Medcalf, T.; Mir, Ll. M.; Quazi, I. S.; Strong, J. A.; Bertin, V.; Botterill, D. R.; Clifft, R. W.; Edgecock, T. R.; Haywood, S.; Edward, M.; Norton, P. R.; Thompson, J. C.; Bloch-Devaux, B.; Colas, P.; Duarte, H.; Emery, S.; Kozanecki, W.; Lançon, E.; Lemaire, M. C.; Locci, E.; Marx, B.; Perez, P.; Rander, J.; Renardy, J.-F.; Rosowsky, A.; Roussarie, A.; Schuller, J.-P.; Schwindling, J.; Si Mohand, D.; Vallage, B.; Johnson, R. P.; Litke, A. M.; Taylor, G.; Wear, J.; Babbage, W.; Booth, C. N.; Buttar, C.; Cartwright, S.; Combley, F.; Dawson, I.; Thompson, L. F.; Barberio, E.; Böhrer, A.; Brandt, S.; Cowan, G.; Grupen, C.; Lutters, G.; Rivera, F.; Schäfer, U.; Smolik, L.; Bosisio, L.; Della Marina, R.; Giannini, G.; Gobbo, B.; Pitis, L.; Ragusa, F.; Bellantoni, L.; Chen, W.; Chen, W.; Conway, J. S.; Feng, Z.; Ferguson, D. P. S.; Gao, Y. S.; Grahl, J.; Harton, J. L.; Hayes, O. J.; Nachtman, J. M.; Pan, Y. B.; Saadi, Y.; Schmitt, M.; Scott, I.; Sharma, V.; Shi, Z. H.; Turk, J. D.; Walsh, A. M.; Weber, F. V.; Sau Lan Wu; Wu, X.; Zheng, M.; Zobernig, G.; Aleph Collaboration

    1994-02-01

    B 0overlineB0 oscillation is studied using almost a million hadronic Z decays collected by the ALEPH experiment at LEP. Events are selected with two leptons present, on opposite sides of the event and with high transverse momentum. The leptons are expected to be dominantly from b decays; a topological vertexing technique is applied to measure the decay length of the b hadrons, and their momentum is determined using an energy-flow method. The fraction of events in which the leptons have the same charge is studied as a function of the measured decay time, and clear evidence is seen for the time-dependent nature of B d0overlineBd0 mixing. The frequency measured for the oscillation corresponds to a mass difference for the Bd0 mass eigenstates Δmd = (3.3 -0.4+0.5 ± 0.7) × 10 -4 eV/ c2. Allowing a second frequency component for the Bs0 a high value for Δms is favoured, leading to the limit Δms > 12 × 10 -4 eV/ c2 (95% CL), from which ( Δm/ Γ) s > 2.0 is derived.

  18. Should bulk cloudwater or fogwater samples obey Henry's law?

    Science.gov (United States)

    Pandis, Spyros N.; Seinfeld, John H.

    1991-06-01

    Mixing of droplets with different pH that are individually in Henry's law equilibrium with the surrounding atmosphere always results in a bulk mixture that is supersaturated with weak acids like S(IV) and HCOOH, and bases like NH3 with respect to the original atmosphere. High supersaturations result only when the pH of the bulk droplet mixture exceeds the pKa of the species, in which pH range large pH differences among droplets of different sizes lead to large deviations from Henry's law for the bulk mixture. The deviation is shown to depend on the ratio of the arithmetic mean to the harmonic mean of the hydrogen ion concentrations of the droplets with the liquid water content used as weighting factor in the calculation of the means. The theory developed can explain observed discrepancies from Henry's law in atmospheric samples and also other observed phenomena like the reported increase of pH values of bulk aqueous samples during storage.

  19. Response of Superheated Droplet Detector (SDD) and Bubble Detector (BD) to interrupted irradiations

    Energy Technology Data Exchange (ETDEWEB)

    Mondal, Prasanna Kumar, E-mail: prasanna_ind_82@yahoo.com; Sarkar, Rupa, E-mail: sarkar_rupa2003@yahoo.com; Chatterjee, Barun Kumar, E-mail: barun_k_chatterjee@yahoo.com

    2017-06-11

    Superheated droplet detectors (SDD) and bubble detectors (BD) are suspensions of micron-sized superheated liquid droplets in inert medium. The metastable droplets can vaporise upon interaction with ionising radiation generating visible bubbles. In this work, we investigated the response of SDD and BD to interrupted neutron irradiations. We observed that the droplet vaporisation rates for SDD and BD are different in nature. The unusual increase in droplet vaporisation rate observed when the SDD is exposed to neutrons after few minutes of radiation-off period is absent for BD. - Highlights: • Superheated droplet detectors (SDD) and bubble detectors (BD) are suspensions of superheated liquid droplets in inert medium. • The bubble nucleation in superheated droplets can be induced by ionising radiation. • The droplet vaporisation rate for SDD is non-monotonic when it is irradiated periodically to neutrons. • For BD the droplet vaporisation rate decrease monotonically when it is irradiated periodically to neutrons.

  20. Photochemistry of U(BH4)4 and U(BD4)4

    International Nuclear Information System (INIS)

    Paine, R.T.; Schonberg, P.R.; Light, R.W.; Danen, W.C.; Freund, S.M.

    1979-01-01

    U(BH 4 ) 4 and U(BD 4 ) 4 are observed to undergo complex degradation reactions promoted by broadband UV radiation. The primary products of these reactions appear to be U(BH 4 ) 3 , B 2 H 6 , H 2 , U(BD 4 ) 3 , B 2 D 6 and D 2 . Further, U(BD 4 ) 4 undergoes a related decomposition reaction under the influence of CO 2 laser irradiation at 924.97 cm -1 . (author)

  1. The Life Span of the BD-PND Bubble Detector

    International Nuclear Information System (INIS)

    Vanhavere, F.; Loos, M.; Thierens, H.

    1999-01-01

    BD-PND bubble detectors from Bubble Technology Industries (BTI) were used to conduct a study of the life span of these detectors. The manufacturer guarantees an optimum detector performance for three months after receipt. Nevertheless, it is important to know the evolution of their characteristics with time, also after those three months. On a standard set-up with a 252 Cf source the bubble detectors were irradiated until they reached the end of their life span. During this period, the evolution in sensitivity was monitored. The temperature compensating system seems to be the limiting factor with time for the use of the BTI bubble detectors. The change in temperature dependence with age was determined. The same parameters were also checked with several batches of detectors that were used in practice. (author)

  2. Rahvaliit : Henri Kaselo süüdistus on idiootsus / Jüri Saar

    Index Scriptorium Estoniae

    Saar, Jüri, 1946-

    2008-01-01

    Keskerakonna Tartumaa piirkonna esimeheks valitud Tartu linnavolinik Henri Kaselo kritiseeris teravalt Rahvaliitu kuuluvaid Tartumaa vallajuhte, kelle juhtimisstiil ja korruptiivne poliitika polevat nõukogude ajast muutunud

  3. Precision measurements in the weak interaction framework: development of realistic simulations for the LPCTrap device installed at GANIL

    International Nuclear Information System (INIS)

    Fabian, Xavier

    2015-01-01

    This work belongs to the effort presently deployed to measure the angular correlation parameter a_β_ν in three nuclear beta decays ("6He"+, "3"5Ar"+ and "1"9Ne"+). The V-A structure of the weak interaction implies that a_β_ν = +1 for a pure Fermi transition and a_β_ν = -1/3 for a pure Gamow-Teller transition. A thorough measurement of this parameter to check any deviation from these values may lead to the discovery of possible exotic currents. Furthermore, the measurement of a_β_ν in mirror transitions allows the extraction of V_u_d, the first element of the Cabibbo-Kobayashi-Maskawa (CKM) matrix. The LPCTrap apparatus, installed at GANIL, is designed to ready a continuous ion beam for injection in a dedicated Paul trap. This latter device allows to have a quasi-punctual source from which the decay products are detected in coincidence. It is from the study of the recoil ion time-of-flight (TOF) distribution that a_β_ν is withdrawn and, since 2010, the associated Shake-Off (SO) probabilities. This study requires the complete simulation of the LPCTrap experiments. The major part of this work is dedicated to such simulations, especially to the modeling of the trapped ion cloud dynamic. The Clouda program, which takes advantage of graphics processing unit (GPU), was developed in this context and its full characterization is presented here. Three important aspects are addressed: the electromagnetic trapping field, the realistic collisions between the ions and the buffer gas atoms and the space charge effect. The present work shows the importance of these simulations to increase the control of the systematic errors on a_β_ν. (author) [fr

  4. [From apprenticeship to Nobel Prize: Henri Moissan's fabulous destiny].

    Science.gov (United States)

    Lafont, O

    2008-01-01

    Born in Paris on September 28, 1852, son of an eastern railways' employee and of a dressmaker, Henri Moissan's secondary schooling in Meaux did not allow him to get access to the sesame diploma "baccalauréat" (GCE). In 1869, he did obtain a special certificate of secondary schooling so that he could become an apprentice in watch making. That could have been the end of the story, but dreadful event for France appeared to have beneficial effects for Moissan. Under the threat of the Prussian army, Moissan's family took refuge near Paris. This gave the young Henri the opportunity to register as a student for the second-class pharmacy diploma, which did not need, at the time, the GCE. Moissan became then a trainee in pharmacy in 1871. Meanwhile, he followed the special schooling of "Ecole de chimie" founded by E. Frémy, and then joined the laboratory of Dehérain at the Museum, where he worked in plant physiology. He finally obtained the famous "baccalauréat" (GCE) and could register as a student in first-class pharmacy. He became a pharmacist as well as a doctor in sciences. In 1883, Moissan was named professor at the school of pharmacy in Paris. In 1886, he isolated fluorine by electrolysis of fluorhydric acid, in the presence of potassium fluoride, at a low temperature. He then studied diamond synthesis and gave a start to high temperature chemistry, designing his famous furnace. These findings and many others allowed Moissan to rise to membership in many learned academies around the world. Crowning achievement, Moissan won the Nobel Prize in 1906. A man of culture, collector of autographs and paintings, he died in 1907. Nothing of that would have been possible if there had not been a second-class pharmacist diploma. The history of Henri Moissan is one of a rise from apprenticeship to the Nobel Prize.

  5. O pensamento crítico de Henri Lefebvre

    Directory of Open Access Journals (Sweden)

    William Gómez Soto

    2012-12-01

    Full Text Available Este trabalho é uma análise da presença de Henri Lefebvre na sociologia brasileira. Lefebvre faz uma leitura crítica de Marx, recuperando o método dialético e propondo uma teoria da vida cotidiana. José de Souza Martins influenciado por Lefebvre e utilizando o método dialético, analisa o processo histórico da constituição do capitalismo brasileiro. Apesar de que há certa presença de Lefebvre na sociologia brasileira, ainda a riqueza de sua obra está para ser descoberta.

  6. Henry Duméry and the sacredness of history

    OpenAIRE

    Labèque, Marcelo Horacio; Pontificia Universidad Católica Argentina

    2014-01-01

    Following the steps of the French phenomenologist HenryDuméry, It is pursued to identify the particularities of what have been called before the «historical sacred», in the most general frame of a «morphology of sacred». In that sense it is intended to demonstrate that the originality of the experience and configuration of the sacred, in both Jewish and Christian religion, comes out from a transformation of cosmic archaic experiences and points of view, leading into a new way of sacred that g...

  7. Edward Henry Sieveking and the demise of essential epilepsy.

    Science.gov (United States)

    Bladin, Peter F

    2008-04-01

    Edward Henry Sieveking, eminent London physician of Victorian times, is best known as the speaker at the historic meeting at which the chairman, Sir Charles Locock, seem to overshadow him in announcing the introduction of bromide--the first effective anti-convulsant. But in fact Sieveking had announced a most important conceptual advance in epileptology--the demise of "essential epilepsy". In addition his book, published soon after and based upon his lecture, is an important historical resumé of Victorian era concepts and management of epilepsy. His important contributions to the understanding and management of this condition are discussed herein.

  8. Henri Ey's neojacksonism and the psychopathology of disintegrated mind.

    Science.gov (United States)

    Farina, Benedetto; Ceccarelli, Maurizio; Di Giannantonio, Massimo

    2005-01-01

    The French psychiatrist Henri Ey developed his organo-dynamic theory of the mind function and consciousness 50 years ago incorporating Hughling Jackson's thinking, along with psychiatric and philosophical theorizations by Janet and Bergson. This model has not received the attention it deserved, but recent advances in neuroscience rekindled interest for Ey's theory. By overcoming the Cartesian mind-body dualism and treating the mind-body unit as an inseparable whole, this model opens the way for the integrated treatment of mental disorders. Ey's conceptualization of consciousness as being simultaneously both synchronous and diachronic anticipates current theories of consciousness (Damasio, Edelman, Mesulam).

  9. Vitamin B@d12@@ concentrations in Mandovi and Zuari estuaries

    Digital Repository Service at National Institute of Oceanography (India)

    De; Rajendran, A.

    Bioassay method using @iCyclotella nana@@ (clone 13) was employed for the estimation of Vitamin B@d12@@ in Mandovi and Zuari estuaries. At the mouth of the Mandovi estuary, B@d12@@ concentration varied between 0.38 and 7.0 ng/l in surface water...

  10. The analysis of B-d ->(eta, eta ')l(+)l(-) decays in the standard model

    NARCIS (Netherlands)

    Erkol, G; Turan, G

    We study the differential branching ratio, the branching ratio and the CP-violating asymmetry for the exclusive B-d --> (eta,eta')l(+)l(-) decays in the standard model. We deduce the B-d --> (eta,eta') form factors from the form factors of B --> pi available in the literature, by using the SU(3)(F)

  11. RVX-297- a novel BD2 selective inhibitor of BET bromodomains

    Energy Technology Data Exchange (ETDEWEB)

    Kharenko, Olesya A., E-mail: olesya@zenithepigenetics.com [Zenith Epigenetics, Suite 300, 4820 Richard Road SW, Calgary, Alberta, T3E 6L1 (Canada); Gesner, Emily M.; Patel, Reena G.; Norek, Karen [Zenith Epigenetics, Suite 300, 4820 Richard Road SW, Calgary, Alberta, T3E 6L1 (Canada); White, Andre; Fontano, Eric; Suto, Robert K. [Xtal BioStructures, Inc., 12 Michigan Dr., Natick, MA 01760 (United States); Young, Peter R.; McLure, Kevin G.; Hansen, Henrik C. [Zenith Epigenetics, Suite 300, 4820 Richard Road SW, Calgary, Alberta, T3E 6L1 (Canada)

    2016-08-12

    Bromodomains are epigenetic readers that specifically bind to the acetyl lysine residues of histones and transcription factors. Small molecule BET bromodomain inhibitors can disrupt this interaction which leads to potential modulation of several disease states. Here we describe the binding properties of a novel BET inhibitor RVX-297 that is structurally related to the clinical compound RVX-208, currently undergoing phase III clinical trials for the treatment of cardiovascular diseases, but is distinctly different in its biological and pharmacokinetic profiles. We report that RVX-297 preferentially binds to the BD2 domains of the BET bromodomain and Extra Terminal (BET) family of protein. We demonstrate the differential binding modes of RVX-297 in BD1 and BD2 domains of BRD4 and BRD2 using X-ray crystallography, and describe the structural differences driving the BD2 selective binding of RVX-297. The isothermal titration calorimetry (ITC) data illustrate the related differential thermodynamics of binding of RVX-297 to single as well as dual BET bromodomains. - Highlights: • A novel inhibitor of BET bromodomains, RVX-297 is described. • The differential binding modes of RVX-297 in BD1 and BD2 domains of BRD4 and BRD2 using X-ray crystallography are described. • RVX-297 preferentially binds to the BD2 domains of the BET bromodomains. • The structural and thermodynamic properties of the BD2 selective binding of RVX-297 are characterized.

  12. Nuclear hBD-1 accumulation in malignant salivary gland tumours.

    NARCIS (Netherlands)

    Wenghoefer, M.H.; Pantelis, A.; Dommisch, H.; Gotz, W.; Reich, R.; Berge, S.J.; Martini, M.; Allam, J.P.; Jepsen, S.; Merkelbach-Bruse, S.; Fischer, H.P.; Novak, N.; Winter, J.

    2008-01-01

    BACKGROUND: Whereas the antimicrobial peptides hBD-2 and -3 are related to inflammation, the constitutively expressed hBD-1 might function as 8p tumour suppressor gene and thus play a key role in control of transcription and induction of apoptosis in malignant epithelial tumours. Therefore this

  13. Increased expression and levels of human β defensins (hBD2 and hBD4 in adults with dental caries

    Directory of Open Access Journals (Sweden)

    Girolamo Jose Barrera

    2013-09-01

    Full Text Available Introduction: Defensins are small anti-microbial peptides produced by epithelial cells. These peptides have a broad range of actions against microorganisms, including Gram-positive and Gram-negative bacteria.Human defensins are classifi ed into two subfamilies, the α-, and β- defensins, which differ in their distribution of disulphide bonds between the six conserved cysteine residues. Defensins are found in salivaand others compartments of the body. Human β defensins 2 (hBD2, beta defensins 4 (hBD4 and alpha defensins 4 (hNP4 in saliva may contributes to vulnerability or resistance to caries. This study aimed to determine a possible correlation between caries and levels of defensins measuring the expression in gingival tissue and concentrations in saliva samples.Methods: Oral examinations were performed on 100 adults of both genders (18-30 years old, and unstimulated whole saliva was collected for immunoassays of the three peptides and for the salivary pH, buffercapacity, protein, and peroxidase activity. mRNA levels of defensins in gingival sample were assessed by semi-quantitative RT-PCR technique.Results: The median salivary levels of hBD2 and hBD4 were 1.88 μg/ml and 0.86 μg/ml respectively for the caries-free group (n=44 and 7.26 μ/ml (hBD2 and 4.25 μg/ml (hBD4 for all subjects with evidenceof caries (n=56. There was no difference in the levels of hNP4, salivary pH, and proteins between groups, however the peroxidase activity and buffer capacity (interval 6.0-5.0 were reduced in caries group. Transcriptional levels of hBD2 and hBD4 did correlate with caries experience, the mRNA expression of hBD2 and hBD4 were signifi cantly higher in patients with caries than in patients with no-caries (p Conclusion: We conclude that high salivary levels and expression of beta defensins, low peroxidase activity and buffer capacity may represent a biological response of oral tissue to caries. Our observation couldlead to new ways to prevent caries

  14. Increased expression and levels of human β defensins (hBD2 and hBD4 in adults with dental caries

    Directory of Open Access Journals (Sweden)

    Girolamo Jose Barrera

    2013-09-01

    Full Text Available Introduction: Defensins are small anti-microbial peptides produced by epithelial cells. These peptides have a broad range of actions against microorganisms, including Gram-positive and Gram-negative bacteria.Human defensins are classifi ed into two subfamilies, the α-, and β- defensins, which differ in their distribution of disulphide bonds between the six conserved cysteine residues. Defensins are found in salivaand others compartments of the body. Human β defensins 2 (hBD2, beta defensins 4 (hBD4 and alpha defensins 4 (hNP4 in saliva may contributes to vulnerability or resistance to caries. This study aimed to determine a possible correlation between caries and levels of defensins measuring the expression in gingival tissue and concentrations in saliva samples.Methods: Oral examinations were performed on 100 adults of both genders (18-30 years old, and unstimulated whole saliva was collected for immunoassays of the three peptides and for the salivary pH, buffercapacity, protein, and peroxidase activity. mRNA levels of defensins in gingival sample were assessed by semi-quantitative RT-PCR technique.Results: The median salivary levels of hBD2 and hBD4 were 1.88 μg/ml and 0.86 μg/ml respectively for the caries-free group (n=44 and 7.26 μ/ml (hBD2 and 4.25 μg/ml (hBD4 for all subjects with evidenceof caries (n=56. There was no difference in the levels of hNP4, salivary pH, and proteins between groups, however the peroxidase activity and buffer capacity (interval 6.0-5.0 were reduced in caries group. Transcriptional levels of hBD2 and hBD4 did correlate with caries experience, the mRNA expression of hBD2 and hBD4 were signifi cantly higher in patients with caries than in patients with no-caries (p < 0.01.Conclusion: We conclude that high salivary levels and expression of beta defensins, low peroxidase activity and buffer capacity may represent a biological response of oral tissue to caries. Our observation couldlead to new ways to prevent

  15. Evaluating Henry's law constant of N-nitrosodimethylamine (NDMA).

    Science.gov (United States)

    Haruta, Shinsuke; Jiao, Wentao; Chen, Weiping; Chang, Andrew C; Gan, Jay

    2011-01-01

    N-Nitrosodimethylamine (NDMA), a potential carcinogen, may contaminate the groundwater when the reclaimed wastewater is used for irrigation and groundwater recharge. Henry's law constant is a critical parameter to assess the fate and transport of reclaimed wastewater-borne NDMA in the soil profile. We conducted a laboratory experiment in which the change of NDMA concentration in water exposed to the atmosphere was measured with respect to time and, based on the data, obtained the dimensionless Henry's law constant (K(H)') of NDMA, at 1.0 x 10(-4). The K(H)' suggests that NDMA has a relatively high potential to volatilize in the field where NDMA-containing wastewater is used for irrigation and the volatilization loss may be a significant pathway of NDMA transport. The experiment was based on the two boundary-layer approach of mass transfer at the atmosphere-water interface. It is an expedient method to delineate K(H)' for volatile or semi-volatile compounds present in water at low concentrations.

  16. VoxHenry: FFT-Accelerated Inductance Extraction for Voxelized Geometries

    KAUST Repository

    Yucel, Abdulkadir C.

    2018-01-18

    VoxHenry, a fast Fourier transform (FFT)-accelerated integral-equation-based simulator for extracting frequency-dependent inductances and resistances of structures discretized by voxels, is presented. VoxHenry shares many features with the popular inductance extractor, FastHenry. Just like FastHenry, VoxHenry solves a combination of the electric volume integral equation and the current continuity equation, but with three distinctions that make VoxHenry suitable and extremely efficient for analyzing voxelized geometries: 1) it leverages a carefully selected set of piecewise-constant and piecewise-linear basis functions; 2) it exploits FFTs to accelerate the matrix-vector multiplications during the iterative solution of system of equations; and 3) it employs a sparse preconditioner to ensure the rapid convergence of iterative solution. VoxHenry is capable of accurately computing frequency-dependent inductances and resistances of arbitrarily shaped and large-scale structures on a desktop computer. The accuracy, efficiency, and applicability of VoxHenry are demonstrated through inductance analysis of various structures, including square and circular coils as well as arrays of RF inductors (situated over ground planes).

  17. 1787 and 1776: Patrick Henry, James Madison, and the Revolutionary Legitimacy of the Constitution.

    Science.gov (United States)

    Banning, Lance

    1988-01-01

    Discusses Patrick Henry's and James Madison's opinions on how the U.S. Constitution should be constructed. Describes how Henry introduced a set of substantive objections which were shared by Antifederalists throughout the country and persuaded many Revolutionaries that the Constitution was essentially at odds with the principles of 1776. (BSR)

  18. Henri Pirenne: Historian and Man of the World

    Directory of Open Access Journals (Sweden)

    Sarah Keymeulen

    2016-12-01

    Full Text Available Henri Pirenne (1862-1935 is generally recognised as one of the most influential European historians of the late nineteenth- and early twentieth-century. The combination of his scholarly activity with the social mission that he set himself earned him an extraordinarily successful career and a double reputation: at least in Belgium, he was regarded not only as a ‘father of history’, but also as great citizen. Although his influence was unmistakably large, there is no consensus about the existence or the nature of a ‘Pirennian persona’. He combined the ideal collection of skills, values and standards required of historians with very specific personal characteristics. At the same time he was inextricably linked to a certain era and a certain Belgium that died with him. Pirenne therefore, did not so much represent a new type of scientific persona as the prestige of an idealised, long-vanished Belgium and its corresponding academic culture. Henri Pirenne. Historicus en man van de wereldHenri Pirenne (1862-1935 wordt beschouwd als één van de meest invloedrijke Europese geschiedschrijvers van de laatnegentiende en vroegtwintigste eeuw. Het verband tussen zijn wetenschappelijke activiteit en de maatschappelijke taak die hij voor zichzelf zag weggelegd, leverde hem een uitzonderlijk succesvolle carrière en een dubbele reputatie op. Pirenne staat, althans in België, immers niet alleen geboekstaafd als een ‘vader van de geschiedenis’, maar ook als een groot staatsburger. Hoewel de invloed van Pirenne onmiskenbaar groot is geweest, is er geen consensus over het bestaan of de aard van een ‘pirenniaanse persona’. Hij combineerde het ideaalpakket van vaardigheden, normen en waarden die historici werden geacht te bezitten met zeer specifieke karaktereigenschappen. Tegelijk was hij onlosmakelijk verknoopt met een zeker tijdsgewricht en een zeker België, dat samen met hem ter ziele ging. Pirenne stond dan ook niet zozeer model voor een nieuw

  19. Henri Pirenne: Historian and Man of the World.

    Directory of Open Access Journals (Sweden)

    S. Keymeulen

    2016-12-01

    Full Text Available Henri Pirenne (1862-1935 is generally recognised as one of the most influential European historians of the late nineteenth- and early twentieth-century. The combination of his scholarly activity with the social mission that he set himself earned him an extraordinarily successful career and a double reputation: at least in Belgium, he was regarded not only as a ‘father of history’, but also as great citizen. Although his influence was unmistakably large, there is no consensus about the existence or the nature of a ‘Pirennian persona’. He combined the ideal collection of skills, values and standards required of historians with very specific personal characteristics. At the same time he was inextricably linked to a certain era and a certain Belgium that died with him. Pirenne therefore, did not so much represent a new type of scientific persona as the prestige of an idealised, long-vanished Belgium and its corresponding academic culture. Henri Pirenne. Historicus en man van de wereld. Henri Pirenne (1862-1935 wordt beschouwd als één van de meest invloedrijke Europese geschiedschrijvers van de laatnegentiende en vroegtwintigste eeuw. Het verband tussen zijn wetenschappelijke activiteit en de maatschappelijke taak die hij voor zichzelf zag weggelegd, leverde hem een uitzonderlijk succesvolle carrière en een dubbele reputatie op. Pirenne staat, althans in België, immers niet alleen geboekstaafd als een ‘vader van de geschiedenis’, maar ook als een groot staatsburger. Hoewel de invloed van Pirenne onmiskenbaar groot is geweest, is er geen consensus over het bestaan of de aard van een ‘pirenniaanse persona’. Hij combineerde het ideaalpakket van vaardigheden, normen en waarden die historici werden geacht te bezitten met zeer specifieke karaktereigenschappen. Tegelijk was hij onlosmakelijk verknoopt met een zeker tijdsgewricht en een zeker België, dat samen met hem ter ziele ging. Pirenne stond dan ook niet zozeer model voor een nieuw

  20. The Cytochrome bd Oxidase of Porphyromonas gingivalis Contributes to Oxidative Stress Resistance and Dioxygen Tolerance.

    Directory of Open Access Journals (Sweden)

    Julia Leclerc

    Full Text Available Porphyromonas gingivalis is an etiologic agent of periodontal disease in humans. The disease is associated with the formation of a mixed oral biofilm which is exposed to oxygen and environmental stress, such as oxidative stress. To investigate possible roles for cytochrome bd oxidase in the growth and persistence of this anaerobic bacterium inside the oral biofilm, mutant strains deficient in cytochrome bd oxidase activity were characterized. This study demonstrated that the cytochrome bd oxidase of Porphyromonas gingivalis, encoded by cydAB, was able to catalyse O2 consumption and was involved in peroxide and superoxide resistance, and dioxygen tolerance.

  1. One-dimensional nodal neutronics routines for the TRAC-BD1 thermal-hydraulics program

    International Nuclear Information System (INIS)

    Nigg, D.W.

    1983-09-01

    Nuclear reactor core transient neutronic behavior is currently modeled in the TRAC-BD1 code using a point-reactor kinetics formulation. This report describes a set of subroutines based on the Analytic Nodal Method that were written to provide TRAC-BD1 with a one-dimensional space-dependent neutronics capability. Use of the routines is illustrated with several test problems. The results of these problems show that the Analytic Nodal neutronics routines have desirable accuracy and computing time characteristics and should be a useful addition to TRAC-BD1

  2. História e psicologia em Henri Berr

    OpenAIRE

    Waeny, Maria Fernanda Costa

    2017-01-01

    O artigo aborda algumas das idéias de Henri Berr; trata de sua proposta em história, especialmente no que ela se opõe à filosofia da história e à história alemãs; e examina como esta concepção de história à la francesa introduz a psicologia nas pesquisas em história e inaugura a psicologia histórica.Palavras-chave: História da Psicologia; Psicologia Histórica; História das Ciências Humanas; História das Idéias; Annales

  3. Henri de Régnier portraitiste du Parnasse

    OpenAIRE

    Mortelette, Yann

    2016-01-01

    Henri de Régnier disait de José-Maria de Heredia qu’il avait fait le lien entre le Parnasse et le symbolisme. Lui-même fit le lien entre le symbolisme et le Parnasse. En 1895, il notait dans son journal intime : « J’ai subi de grandes influences. Aux premiers jours, Mallarmé m’a […] nettoyé l’esprit ; j’en ai été affiné et ankylosé. Puis j’ai subi les contacts plus vivants d’Heredia. » Cette seconde influence contrebalança la première. Régnier fréquenta les samedis de la rue Balzac avec autan...

  4. Thinking in time an introduction to Henri Bergson

    CERN Document Server

    Guerlac, Suzanne

    2006-01-01

    "In recent years, we have grown accustomed to philosophical language that is intensely self-conscious and rhetorically thick, often tragic in tone. It is enlivening to read Bergson, who exerts so little rhetorical pressure while exacting such a substantial effort of thought. . . . Bergson's texts teach the reader to let go of entrenched intellectual habits and to begin to think differently—to think in time. . . . Too much and too little have been said about Bergson. Too much, because of the various appropriations of his thought. Too little, because the work itself has not been carefully studied in recent decades."—from Thinking in TimeHenri Bergson (1859–1941), whose philosophical works emphasized motion, time, and change, won the Nobel Prize for Literature in 1927. His work remains influential, particularly in the realms of philosophy, cultural studies, and new media studies. In Thinking in Time, Suzanne Guerlac provides readers with the conceptual and contextual tools necessary for informed appreciati...

  5. GANIL status report

    International Nuclear Information System (INIS)

    Bajard, M.

    1992-01-01

    Following the OAE (augmentation of energy) modification and the installation of the SME (medium energy facility) the accelerator has been operating for three years with the new ECR source (CAPRICE IIB at 10GHz). Results obtained with new beams, metallic beams and the first tests with the new injector system using an ECR source installed on a 100 kV platform are given. (author) 9 refs., 4 figs., 4 tabs

  6. W.E. Henry Symposium compendium: The importance of magnetism in physics and material science

    Energy Technology Data Exchange (ETDEWEB)

    Carwell, H.

    1997-09-19

    This compendium contains papers presented at the W. E. Henry Symposium, The Importance of Magnetism in Physics and Material Science. The one-day symposium was conducted to recognize the achievements of Dr. Warren Elliot Henry as educator, scientist, and inventor in a career spanning almost 70 years. Dr. Henry, who is 88 years old, attended the symposium. Nobel Laureate, Dr. Glenn Seaborg, a friend and colleague for over 40 years, attended the event and shared his personal reminiscences. Dr. Seaborg is Associate Director-At-Large at the Lawrence Berkeley National Laboratory. The Compendium begins with three papers which demonstrate the ongoing importance of magnetism in physics and material science. Other contributions cover the highlights of Dr. Henry`s career as a researcher, educator, and inventor. Colleagues and former students share insights on the impact of Dr. Henry`s research in the field of magnetism, low temperature physics, and solid state physics; his influence on students as an educator; and his character, intellect and ingenuity, and passion for learning and teaching. They share a glimpse of the environment and times that molded him as a man, and the circumstances under which he made his great achievements despite the many challenges he faced.

  7. Expression of beta-defensins pBD-1 and pBD-2 along the small intestinal tract of the pig: lack of upregulation in vivo upon Salmonella typhimurium infection.

    Science.gov (United States)

    Veldhuizen, Edwin J A; van Dijk, Albert; Tersteeg, Monique H G; Kalkhove, Stefanie I C; van der Meulen, Jan; Niewold, Theo A; Haagsman, Henk P

    2007-01-01

    Defensins are antimicrobial peptides that play an important role in the innate immune response in the intestine. Up to date, only one beta-defensin (pBD-1), has been described in pig, which was found to be expressed at low levels in the intestine. We set-up a quantitative PCR method to detect the gene expression of pBD-1 and a newly discovered porcine beta-defensin, pBD-2. Expression of pBD-1 mRNA increased from the proximal to the distal part of the intestine whereas pBD-2 expression decreased. The main gene expression sites for pBD-2 were kidney and liver, whereas pBD-1 was mainly expressed in tongue. The porcine small intestinal segment perfusion (SISP) technique was used to investigate effects of Salmonella typhimurium DT104 on intestinal morphology and pBD-1 and pBD-2 mRNA levels in vivo. The early responses were studied 2, 4 and 8 h post-infection in four separate jejunal and ileal segments. Immunohistochemistry showed invasion of the mucosa by Salmonella and changes in intestinal morphology. However, no concomitant changes in expression of either pBD-1 or pBD-2 were observed. We conclude that at least two defensins are differentially expressed in the intestine of pigs, and that expression of both defensins is not altered by S. typhimurium under these conditions.

  8. [Protokolle der Estländischen Ritterschaft 1914-1920. Bd 1-2] / Mati Laur

    Index Scriptorium Estoniae

    Laur, Mati, 1955-

    2012-01-01

    Arvustus: Protokolle der Estländischen Ritterschaft 1914-1920. Bd. 1-2 (Ex fontibus archivi Estoniae, 3). Hrsg. von Thomas Freiherr von Dellingshausen und Henning von Wistingshausen. (Tartu: Eesti Ajalooarhiiv, 2011)

  9. Nuclear hBD-1 accumulation in malignant salivary gland tumours

    International Nuclear Information System (INIS)

    Wenghoefer, M; Merkelbach-Bruse, S; Fischer, HP; Novak, N; Winter, J; Pantelis, A; Dommisch, H; Götz, W; Reich, R; Bergé, S; Martini, M; Allam, JP; Jepsen, S

    2008-01-01

    Whereas the antimicrobial peptides hBD-2 and -3 are related to inflammation, the constitutively expressed hBD-1 might function as 8p tumour suppressor gene and thus play a key role in control of transcription and induction of apoptosis in malignant epithelial tumours. Therefore this study was conducted to characterise proteins involved in cell cycle control and host defence in different benign and malignant salivary gland tumours in comparison with healthy salivary gland tissue. 21 paraffin-embedded tissue samples of benign (n = 7), and malignant (n = 7) salivary gland tumours as well as healthy (n = 7) salivary glands were examined immunohistochemically for the expression of p53, bcl-2, and hBD-1, -2, -3. HBD-1 was distributed in the cytoplasm of healthy salivary glands and benign salivary gland tumours but seems to migrate into the nucleus of malignant salivary gland tumours. Pleomorphic adenomas showed cytoplasmic as well as weak nuclear hBD-1 staining. HBD-1, 2 and 3 are traceable in healthy salivary gland tissue as well as in benign and malignant salivary gland tumours. As hBD-1 is shifted from the cytoplasm to the nucleus in malignant salivary gland tumours, we hypothesize that it might play a role in the oncogenesis of these tumours. In pleomorphic adenomas hBD-1 might be connected to their biologic behaviour of recurrence and malignant transformation

  10. Guillem Fabre, “Pus dels majors” (BdT 216.2; Id., “Hon mais vey, pus truep sordeyor” (BdT 216.1

    Directory of Open Access Journals (Sweden)

    Linda Paterson

    2013-03-01

    Full Text Available The historical circumstances of Guillem Fabre’s two surviving sirventes has given rise to widely divergent views. This essay builds on Parducci’s contextualisation of BdT 216.2 during the War of the Sicilian Vespers and the so-called Aragonese crusade by the French against Pere III of Aragon in 1284-1285. It argues that Guillem is likely to be referring to events say entre nos because Narbonne was the focal point of the gathering French army and preaching of the crusade. All other textual details are compatible with this period and best explained by this context. But while Parducci places the sirventes in May 1285, it must in fact have preceded the death of Martin IV on 29 March, since his speedily-appointed successor Honorius IV could not be blamed for not having preached a crusade against the heathen before the conflict degenerated into further atrocities. Furthermore a slightly earlier timing better explains the allusion to “the best-known man in the world”, the obvious candidate at this time being Charles of Anjou. Guillem probably composed BdT 216.2 during the build-up to war in 1284, before the death of Charles in January 1285, during the period of war preparations and propaganda speeches. It is also argued here that, pace Parducci, BdT 216.1 did not necessarily precede BdT 216.2.

  11. Restauration de la statue de Henri IV

    Directory of Open Access Journals (Sweden)

    Stéphanie Celle

    2012-04-01

    Full Text Available Cette intervention de conservation du bronze de la statue de Henri IV était la première depuis sa création en 1818 : on héritait de la surface originale de l’œuvre altérée par les vicissitudes du temps et les événements historiques traversés. Le protocole de conservation se voulait respectueux de cette authenticité de la patine et a cherché à en laisser les marques tout en apportant une réponse pour contrer la corrosion active de l’alliage. C’est en conformité aux principes de conservation établis par Cesare Brandi, qu’ont été définis le nettoyage sélectif des surfaces et l’application de couches protectives sur le bronze. Par ailleurs, le moment du chantier est un moment privilégié pour observer un monument et mieux connaître son histoire particulière. Ce chantier nous a permis de redécouvrir deux ensembles de boîtes déposées dans l’antre du cheval dans des situations parfois surprenantes.This conservation treatment for the bronze statue of Henri IV is the first since its creation in 1818. While the original surface of the work remains, it has been altered by natural and human forces; including the weathering of the material from exposure to the elements and damage caused by historic events. The conservation protocol is respectful of this authenticity of the surface patina and the marks of damage due to historical events, while developing a treatment plan to counter the active corrosion of the alloy. In keeping with the principles of conservation established by Cesare Brandi, the treatment program defines the selective cleaning of the surface and the application of several layers of a protective coating on the bronze. In addition, the conservation project is an opportunity to carefully study a monument to better understand its unique history. This project allowed us to rediscover two sets of boxes placed inside the cavity of the horse; an unxpected discovery.

  12. The personality of Henry Cavendish a great scientist with extraordinary peculiarities

    CERN Document Server

    McCormmach, Russell

    2014-01-01

    This book explores the 18th century natural philosopher Henry Cavendish, best known for his work in chemistry and physics. It traces aspects of his personality, views and interpretations of him, and explores notions of eccentricity and autism.

  13. NOAA Ship Henry B. Bigelow Underway Meteorological Data, Near Real Time

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NOAA Ship Henry B. Bigelow Underway Meteorological Data (Near Real Time, updated daily) are from the Shipboard Automated Meteorological and Oceanographic System...

  14. Hiina kompartei pole NLKP-ga võrreldav / Henri Kaselo

    Index Scriptorium Estoniae

    Kaselo, Henri

    2005-01-01

    20.-26. novembril Hiinas Pekingis ja sadamalinnas Tianjinis peetud Euroopa ja Aasia noorte kohtumisest, kus Eestit esindasid Keskerakonna noortekogu esimees Henri Kaselo ja Euroopa Noorte Sotsiaaldemokraatide aseesimees ning Toomas Hendrik Ilvese nõunik Rander Läntsi

  15. Strelku vsjo ravno perevedut. No v kakuju storonu? / Henry Posner ; interv. Eteri Kekelidze

    Index Scriptorium Estoniae

    Posner, Henry

    2006-01-01

    Eesti Raudtee üks erastajaist, RDC juht Henry Posner III meenutab ER erastamist 2001. a., investeeringutest, reeglite muutmisest, Eesti Raudtee müümise põhjustest, Eesti transiidi tulevikust. Diagramm: Eesti Raudtee kasum 1998-2004

  16. 2008 USGS Lidar: Twelve County, Illinois (Grundy, Kane, McHenry only)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This LiDAR data is within Illinois Department of Transportation districts 1 and 3 covering Grundy, Kane and McHenry counties. The data is updated from its original...

  17. Why it was natural for Henri Becquerel to discover natural radioactivity

    International Nuclear Information System (INIS)

    Barquins, M.

    2002-01-01

    This article presents the scientific saga of the Becquerel family. 4 generations of Becquerel Antoine-Cesar (1788-1878), Edmond (1820-1891), Henri (1852-1906) and Jean (1878-1953) were involved in scientific activities at the highest level. Henri was awarded the Nobel prize of physics (shared with Pierre and Marie Curie) in 1903 for the discovery of radioactivity. The author shows that the discovery of radioactivity was due to talent, family emulation, genetics and chance. (A.C.)

  18. 46 CFR 7.55 - Cape Henry, VA to Cape Fear, NC.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 1 2010-10-01 2010-10-01 false Cape Henry, VA to Cape Fear, NC. 7.55 Section 7.55 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY PROCEDURES APPLICABLE TO THE PUBLIC BOUNDARY LINES Atlantic Coast § 7.55 Cape Henry, VA to Cape Fear, NC. (a) A line drawn from Rudee Inlet Jetty Light “2” to...

  19. The advantage of using the henry straight line in {gamma} spectrometry (1963); Interet de l'utilisation de la droite de henry en spectrometrie {gamma} (1963)

    Energy Technology Data Exchange (ETDEWEB)

    Jockey, [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1963-07-01

    The Henry construction is a convenient way to interpret the total absorption peaks in gamma spectrometry by exploiting their statistical significance. It is so possible to determine graphically, and accurately, such values as: - position of the peak - resolution, etc. The main practical applications are considered. (author) [French] La construction de la droite de Henry fournit un moyen commode d'interpreter les pics d'absorption totale en spectrometrie gamma en exploitant leur signification statistique, il est ainsi possible de determiner graphiquement, avec precision, des notions telles que: - position du pic - resolution, etc. Les principales applications pratiques sont envisagees. (auteur)

  20. A MULTI-WAVELENGTH 3D MODEL OF BD+30°3639

    Energy Technology Data Exchange (ETDEWEB)

    Freeman, M. J.; Kastner, Joel H. [Chester F. Carlson Center for Imaging Science, School of Physics and Astronomy, and Laboratory for Multiwavelength Astrophysics, Rochester Institute of Technology, 54 Lomb Memorial Drive, Rochester NY 14623 (United States)

    2016-10-01

    We present a 3D multi-wavelength reconstruction of BD+30°3639, one of the best-studied planetary nebulae in the solar neighborhood. BD+30°3639, which hosts a [WR]-type central star, has been imaged at wavelength regimes that span the electromagnetic spectrum, from radio to X-rays. We have used the astrophysical modeling software SHAPE to construct a 3D morpho-kinematic model of BD+30°3639. This reconstruction represents the most complete 3D model of a PN to date from the standpoint of the incorporation of multi-wavelength data. Based on previously published kinematic data in optical emission lines and in lines of CO (radio) and H{sub 2} (near-IR), we were able to reconstruct BD+30's basic velocity components assuming a set of homologous velocity expansion laws combined with collimated flows along the major axis of the nebula. We confirm that the CO “bullets” in the PN lie along an axis that is slightly misaligned with respect to the major axis of the optical nebula, and that these bullets are likely responsible for the disrupted structures of the ionized and H{sub 2}-emitting shells within BD+30. Given the relative geometries and thus dynamical ages of BD+30's main structural components, it is furthermore possible that the same jets that ejected the CO bullets are responsible for the generation of the X-ray-emitting hot bubble within the PN. Comparison of alternative viewing geometries for our 3D reconstruction of BD+30°3639 with imagery of NGC 40 and NGC 6720 suggests a common evolutionary path for these nebulae.

  1. Henry Beecher's Contributions to the Ethics of Clinical Research.

    Science.gov (United States)

    Veatch, Robert M

    2016-01-01

    In the 1950s and '60s, Henry Beecher pioneered the discussion of the ethics of clinical research, leading eventually to the publication of the famous New England Journal of Medicine article summarizing 22 research studies that Beecher suggests were unethical. Those studies generally showed a pattern of posing serious risks to subjects without anticipated proportional benefit. Beecher famously claimed that the problem was not that researchers were malicious or evil; rather, he claimed the problem was they manifested thoughtlessness or carelessness. He called for more rigorous self-scrutiny rather than public review.This article argues that Beecher's reliance on conscientious investigators is problematic. In particular, it focuses on benefits and harms to the exclusion of other moral criteria. However, both research subjects and public regulators are also concerned about autonomy and the consent requirement, confidentiality, and fairness in subject selection and research design. The movement in the 1970s toward more public scrutiny was critical, even though Beecher was right in holding that it was not "vicious disregard for subject welfare" that explained unethical protocols.

  2. The enigmatic figure of Dr Henry Maudsley (1835-1918).

    Science.gov (United States)

    Pantelidou, Maria; Demetriades, Andreas K

    2014-08-01

    In spite of his contribution to psychiatry in 19th century Britain, Henry Maudsley remains a mysterious figure, a man mostly known for his donation to the London County Council for the building of the Maudsley Hospital and for The Maudsley Annual Lecture created in honour of his benevolence. Besides Sir Aubrey Lewis' article in 1951 and Michael Collie's attempt in 1988 to construct a biographical study on Maudsley, there does not seem to be any current endeavour to tell the story of his life, whereas Trevor Turner's contribution to the 2004 Oxford Dictionary of National Biography gives a somewhat scathing but unattributed account of Maudsley's personality. This essay attempts to explore his contributions to the Medico-Psychological Association (MPA), the current Royal College of Psychiatrists, his editorship of the Journal of Mental Health (currently named the British Journal of Psychiatry), his literary contributions and his vision for a psychiatric hospital. This essay is an attempt to demystify his figure and to explore some of the rumours and criticisms surrounding his name and the reasons why so little has been written about him. It is also a venture to unravel his complex personality and his intricate philosophy. © The Author(s) 2014 Reprints and permissions: sagepub.co.uk/journalsPermissions.nav.

  3. Clinical management and burden of bipolar disorder: a multinational longitudinal study (WAVE-bd Study

    Directory of Open Access Journals (Sweden)

    Moreno-Manzanaro Miriam

    2011-04-01

    Full Text Available Abstract Background Studies in bipolar disorder (BD to date are limited in their ability to provide a whole-disease perspective - their scope has generally been confined to a single disease phase and/or a specific treatment. Moreover, most clinical trials have focused on the manic phase of disease, and not on depression, which is associated with the greatest disease burden. There are few longitudinal studies covering both types of patients with BD (I and II and the whole course of the disease, regardless of patients' symptomatology. Therefore, the Wide AmbispectiVE study of the clinical management and burden of Bipolar Disorder (WAVE-bd (NCT01062607 aims to provide reliable information on the management of patients with BD in daily clinical practice. It also seeks to determine factors influencing clinical outcomes and resource use in relation to the management of BD. Methods WAVE-bd is a multinational, multicentre, non-interventional, longitudinal study. Approximately 3000 patients diagnosed with BD type I or II with at least one mood event in the preceding 12 months were recruited at centres in Austria, Belgium, Brazil, France, Germany, Portugal, Romania, Turkey, Ukraine and Venezuela. Site selection methodology aimed to provide a balanced cross-section of patients cared for by different types of providers of medical aid (e.g. academic hospitals, private practices in each country. Target recruitment percentages were derived either from scientific publications or from expert panels in each participating country. The minimum follow-up period will be 12 months, with a maximum of 27 months, taking into account the retrospective and the prospective parts of the study. Data on demographics, diagnosis, medical history, clinical management, clinical and functional outcomes (CGI-BP and FAST scales, adherence to treatment (DAI-10 scale and Medication Possession Ratio, quality of life (EQ-5D scale, healthcare resources, and caregiver burden (BAS scale

  4. High Milk-Clotting Activity Expressed by the Newly Isolated Paenibacillus spp. Strain BD3526

    Directory of Open Access Journals (Sweden)

    Feng Hang

    2016-01-01

    Full Text Available Paenibacillus spp. BD3526, a bacterium exhibiting a protein hydrolysis circle surrounded with an obvious precipitation zone on skim milk agar, was isolated from raw yak (Bos grunniens milk collected in Tibet, China. Phylogenetic analysis based on 16S rRNA and whole genome sequence comparison indicated the isolate belong to the genus Paenibacillus. The strain BD3526 demonstrated strong ability to produce protease with milk clotting activity (MCA in wheat bran broth. The protease with MCA was predominantly accumulated during the late-exponential phase of growth. The proteolytic activity (PA of the BD3526 protease was 1.33-fold higher than that of the commercial R. miehei coagulant. A maximum MCA (6470 ± 281 SU mL−1 of the strain BD3526 was reached under optimal cultivation conditions. The protease with MCA was precipitated from the cultivated supernatant of wheat bran broth with ammonium sulfate and purified by anion-exchange chromatography. The molecular weight of the protease with MCA was determined as 35 kDa by sodium dodecyl sulfate-polyacrylamide gels electrophoresis (SDS-PAGE and gelatin zymography. The cleavage site of the BD3526 protease with MCA in κ-casein was located at the Met106–Ala107 bond, as determined by mass spectrometry analysis.

  5. The Works of Henry Moseley, 1887-1915

    Science.gov (United States)

    Scerri, Eric

    2013-04-01

    In 1913 Henry Moseley, an unknown young English physicist published an article in the Philosophical Magazine under the title of ``The High Frequency Spectra of the Elements.'' The 10-page article was to have far reaching implications in both chemistry and physics and helped to resolve a major conundrum in the periodic table of the elements. The talk will briefly examine the life and work of Moseley who died tragically while fighting in the trenches of World War I in 1915. The build-up to the discovery of atomic number took several different avenues including contributions from Rutherford and Barkla. However the more direct motivation for Moseley's work, as he readily acknowledged, were the articles of an unknown Dutch econometrician Anton Van den Broek who attempted to improve on Mendeleev's periodic table. Moseley began as a student of Rutherford at Manchester and took a keen interest in the development of research using X-rays following the work of Roentgen, von Laue and Bragg. Although Rutherford was at first reluctant to enter this new field he soon yielded to young Moseley's request and sent him to Leeds for brief training with Bragg. On returning to Manchester, Moseley devised an ingenious apparatus in which a set of metal samples could be rotated so as to become the target for a beam of electrons in order to measure the frequencies of the emitted K X-rays. The first set of such experiments used nine successive elements in the periodic table, from titanium to zinc. Moseley's now immense fame rests with the results of this study as well as a subsequent one which extended the study into a further 30 elements, in addition to the use that his method was put to by himself as well as subsequent chemists and physicists.

  6. [Hypospadia and infertility of Henry II of France (1519-1559)].

    Science.gov (United States)

    Hatzinger, M; Al-Shajlawi, S; Sohn, M

    2014-03-01

    Henry II (1519-1559) of France was the second son of Francis I (1494-1547) and Claude de France (1498-1524) born in 1519 in St. Germain-en-Laye. After his older brother's and his father's death in 1547, he was anointed the French king in Reims. In 1533 already, as a 14-year-old boy, for reasons of state, he was married to the same aged Catherine de Medici (1519-1589), as her uncle was Pope Clement VII (1478-1534). The marriage remained childless for 11 years since Henry, due to a distinct hypospadia and a completely sexually inexperienced wife was unable to conceive children with her. His existing liaison to Diane de Poitiers (1499-1566) - a 19-year-older maid of honor of his father Francis I from 1537 until his death - influenced his sexual life immensely.The blame for the childless marriage was placed primarily on his wife, as Henry had become father of an illegitimate daughter with a mistress. Catherine then underwent all possible medical and alchemical procedures to finally give birth to the hoped Dauphin. Ironically, her rival for the favor of her husband, Diane de Poitiers was one of her greatest allies. She made clear that the cause lay with Henry and not with his wife. This was confirmed by the added solid physician Jean Fernel (1497-1558). His treatment of Henry and the simultaneous training of the unexperienced Catherine by Diane de Poitiers led to success.The result was the birth of Francis II (1544-1560) in 1544, the first of 10 children in 12 years. Thus, the dynasty was saved. After the death of Henry in a tragic tournament accident in 1559, three of his sons became kings of France. But the line of Valois remained without further descendants and was continued by Henry IV, the first Bourbon king in 1589.

  7. Anonimi, “Ges al meu grat non sui joglar” (BdT 461.126, “Per zo no·m voil desconortar” (BdT 461.193, “Va, cobla: al Juge de Galur” (BdT 461.246, “Seigner Juge, ben aug dir a la gen” (BdT 461.217, “Ges per li diz non er bons prez sabuz” (BdT 461.133

    Directory of Open Access Journals (Sweden)

    Giuseppe Noto

    2012-09-01

    Full Text Available My paper provides a new critical edition, with critical apparatus, comment and translation of a set of anonymous ‘coblas’, copied as a sequence in the anthology present at ff. 55-66 in chansonnier P: BdT 461.126; BdT 461.193; BdT 461.246; BdT 461.217; BdT 461.133 (all of which are unica. I will examine in particular the attributions suggested so far for one or more of these ‘coblas’ (a name that has frequently been put forward is that of Paolo Lanfranchi da Pistoia, author of the sonnet in ‘cobla’ form copied in P immediately preceding the poems discussed here and address the hypothesis put forward by several scholars (and upheld with convincing evidence by Stefano Asperti that the sequence under consideration points to the strong presence of a Tuscan tradition in chansonnier P, clearly contributing, among other things, to outline a “fundamental coherence” (Asperti between some aspects of Dante’s literary culture and this particular songbook.

  8. The Unusual Resistance of Avian Defensin AvBD7 to Proteolytic Enzymes Preserves Its Antibacterial Activity.

    Science.gov (United States)

    Bailleul, Geoffrey; Kravtzoff, Amanda; Joulin-Giet, Alix; Lecaille, Fabien; Labas, Valérie; Meudal, Hervé; Loth, Karine; Teixeira-Gomes, Ana-Paula; Gilbert, Florence B; Coquet, Laurent; Jouenne, Thierry; Brömme, Dieter; Schouler, Catherine; Landon, Céline; Lalmanach, Gilles; Lalmanach, Anne-Christine

    2016-01-01

    Defensins are frontline peptides of mucosal immunity in the animal kingdom, including birds. Their resistance to proteolysis and their ensuing ability to maintain antimicrobial potential remains questionable and was therefore investigated. We have shown by bottom-up mass spectrometry analysis of protein extracts that both avian beta-defensins AvBD2 and AvBD7 were ubiquitously distributed along the chicken gut. Cathepsin B was found by immunoblotting in jejunum, ileum, caecum, and caecal tonsils, while cathepsins K, L, and S were merely identified in caecal tonsils. Hydrolysis product of AvBD2 and AvBD7 incubated with a panel of proteases was analysed by RP-HPLC, mass spectrometry and antimicrobial assays. AvBD2 and AvBD7 were resistant to serine proteases and to cathepsins D and H. Conversely cysteine cathepsins B, K, L, and S degraded AvBD2 and abolished its antibacterial activity. Only cathepsin K cleaved AvBD7 and released Ile4-AvBD7, a N-terminal truncated natural peptidoform of AvBD7 that displayed antibacterial activity. Besides the 3-stranded antiparallel beta-sheet typical of beta-defensins, structural analysis of AvBD7 by two-dimensional NMR spectroscopy highlighted the restricted accessibility of the C-terminus embedded by the N-terminal region and gave a formal evidence of a salt bridge (Asp9-Arg12) that could account for proteolysis resistance. The differential susceptibility of avian defensins to proteolysis opens intriguing questions about a distinctive role in the mucosal immunity against pathogen invasion.

  9. Assessment of a new interfacial friction correlation in TRAC-BD1/MOD1

    International Nuclear Information System (INIS)

    Analytis, G.T.

    1986-01-01

    Analysis of a number of 5-bar (and one 1-bar) boiloff experiments in the electrically heated 33-rod bundle NEPTUN at the Swiss Federal Institute for Reactor Research by TRAC-BD1 version 12 and MOD1 has shown that the code consistently underpredicts the collapsed liquid level histories, hence predicting earlier critical heat fluxes and higher peak rod surface temperatures than the measurements showed. Moreover, recent work has demonstrated that these differences can be attributed to the bubbly/churn interfacial friction model in TRAC-BD1 (resulting in rather large interfacial drag) whose appropriateness for rod bundles is questionable; decreasing the interfacial drag resulted in excellent agreement between measurements and code predictions. Recent analysis of boiloff experiments with the French code CATHARE and with a bubbly/churn interfacial drag force f/sub i/ similar to the one of TRAC-BD1 has also resulted in the underprediction of collapsed liquid level histories. In this work, it was shown that the usual vapor drift velocity correlations (through which f/sub i/ is derived) for this flow regime developed for tubes are not appropriate for rod bundles. Moreover, a new f/sub i/ correlation for bubbly/churn flow in rod bundles was developed based on the Froude number. The authors have modified this correlation slightly, implemented it in TRAC-BD1/MOD1, and reanalyzed most of the boiloff experiments in NEPTUN

  10. Lightcurve Analysis for Near-Earth Asteroid (143404) 2003 BD44

    Science.gov (United States)

    Polakis, Tom; Warner, Brian D.; Skiff, Brian A.

    2018-01-01

    The synodic rotation period has been determined for the near-Earth asteroid (NEA) (143404) 2003 BD44. The asteroid was observed during three intervals with a rotation period on the order of 79 h determined in each case. The lightcurve exhibited rapidly changing morphology as the asteroid approached. Data have submitted to the ALCDEF database.

  11. Relative accuracy of the BD Logic and FreeStyle blood glucose meters.

    Science.gov (United States)

    2007-04-01

    The BD Logic((R)) (Becton, Dickinson and Co., Franklin Lakes, NJ) and FreeStyle((R)) (Abbott Diabetes Care, Alameda, CA) meters are used to transmit data directly to insulin pumps for calculation of insulin doses and to calibrate continuous glucose sensors as well as to monitor blood glucose levels. The accuracy of the two meters was evaluated in two inpatient studies conducted by the Diabetes Research in Children Network (DirecNet). In both studies, meter glucose measurements made with either venous or capillary blood were compared with reference glucose measurements made by the DirecNet Central Laboratory at the University of Minnesota using a hexokinase enzymatic method. The BD Logic tended to read lower than the laboratory reference regardless of whether venous (median difference = -9 mg/dL) or capillary blood (median difference = -7 mg/dL) was used. This resulted in lower accuracy of the BD Logic compared with the FreeStyle meter based on the median relative absolute difference (RAD) for both venous blood (median RAD, 9% vs. 5%, P blood (median RAD, 11% vs. 6%, P = 0.008). The greatest discrepancy in the performance of the two meters was at higher reference glucose values. Accuracy was not significantly different when the reference was < or = 70 mg/dL. The BD Logic meter is less accurate than the FreeStyle meter.

  12. checkCIF/PLATON report Datablock: monika-bd1re3

    Indian Academy of Sciences (India)

    IF USED AS PART OF A REVIEW PROCEDURE. FOR PUBLICATION, IT SHOULD NOT REPLACE THE EXPERTISE OF AN EXPERIENCED. CRYSTALLOGRAPHIC REFEREE. No syntax errors found. CIF dictionary Interpreting this report. Datablock: monika-bd1re3. Bond precision: C-C = 0.0046 A. Wavelength=0.71073.

  13. Label-free biochips for rapid detection of soybean allergen GlymBd ...

    African Journals Online (AJOL)

    detection. Keywords: Soybean Allergen, Gly mBd 30K, Biochip, Detection, Foods ... methods of choice by food industries and food .... shrimp, fish, peanut, wheat, and graham bread served as negative controls. Manufactured foods such as cream cake, cereal bar, chocolate biscuits, and pineapple cake were screened for.

  14. AutoBD: Automated Bi-Level Description for Scalable Fine-Grained Visual Categorization.

    Science.gov (United States)

    Yao, Hantao; Zhang, Shiliang; Yan, Chenggang; Zhang, Yongdong; Li, Jintao; Tian, Qi

    Compared with traditional image classification, fine-grained visual categorization is a more challenging task, because it targets to classify objects belonging to the same species, e.g. , classify hundreds of birds or cars. In the past several years, researchers have made many achievements on this topic. However, most of them are heavily dependent on the artificial annotations, e.g., bounding boxes, part annotations, and so on . The requirement of artificial annotations largely hinders the scalability and application. Motivated to release such dependence, this paper proposes a robust and discriminative visual description named Automated Bi-level Description (AutoBD). "Bi-level" denotes two complementary part-level and object-level visual descriptions, respectively. AutoBD is "automated," because it only requires the image-level labels of training images and does not need any annotations for testing images. Compared with the part annotations labeled by the human, the image-level labels can be easily acquired, which thus makes AutoBD suitable for large-scale visual categorization. Specifically, the part-level description is extracted by identifying the local region saliently representing the visual distinctiveness. The object-level description is extracted from object bounding boxes generated with a co-localization algorithm. Although only using the image-level labels, AutoBD outperforms the recent studies on two public benchmark, i.e. , classification accuracy achieves 81.6% on CUB-200-2011 and 88.9% on Car-196, respectively. On the large-scale Birdsnap data set, AutoBD achieves the accuracy of 68%, which is currently the best performance to the best of our knowledge.Compared with traditional image classification, fine-grained visual categorization is a more challenging task, because it targets to classify objects belonging to the same species, e.g. , classify hundreds of birds or cars. In the past several years, researchers have made many achievements on this topic

  15. Evaluation of the BD Max Cdiff assay for the detection of toxigenic Clostridium difficile in human stool specimens.

    Science.gov (United States)

    Putsathit, Papanin; Morgan, Justin; Bradford, Damien; Engelhardt, Nelly; Riley, Thomas V

    2015-02-01

    The Becton Dickinson (BD) PCR-based GeneOhm Cdiff assay has demonstrated a high sensitivity and specificity for detecting Clostridium difficile. Recently, the BD Max platform, using the same principles as BD GeneOhm, has become available in Australia. This study aimed to investigate the sensitivity and specificity of BD Max Cdiff assay for the detection of toxigenic C. difficile in an Australian setting. Between December 2013 and January 2014, 406 stool specimens from 349 patients were analysed with the BD Max Cdiff assay. Direct and enrichment toxigenic culture were performed on bioMérieux ChromID C. difficile agar as a reference method. isolates from specimens with discrepant results were further analysed with an in-house PCR to detect the presence of toxin genes. The overall prevalence of toxigenic C. difficile was 7.2%. Concordance between the BD Max assay and enrichment culture was 98.5%. The sensitivity, specificity, positive predictive value and negative predictive value for the BD Max Cdiff assay were 95.5%, 99.0%, 87.5% and 99.7%, respectively, when compared to direct culture, and 91.7%, 99.0%, 88.0% and 99.4%, respectively, when compared to enrichment culture. The new BD Max Cdiff assay appeared to be an excellent platform for rapid and accurate detection of toxigenic C. difficile.

  16. Software package developments around TAPS multidetector: on-line management of GANIL data; mesons neutral identification with the help of neural networks

    International Nuclear Information System (INIS)

    Lefevre, F.

    1993-02-01

    The photon multidetector system TAPS, a European collaboration, was installed for the second series of experiments at GANIL in the fall of 1992. It was used in conjunction with a multidetector for charged particles and the high resolution spectrometer SPEG. This experimental set-up is described. A dedicated software package, written in the PAW environment, for the online control and analysis of data has been developed and is described in detail. One aspect of the TAPS experimental program involves the detection of neutral mesons via two-photon decay. The identification by this decay channel is not trivial due to the so-called combinatorial background-the generation of photon pairs not associated with a meson decay. A method based on a neural network has been developed in order to aid in the extraction of the meson signal. The method is based on that of Hopfield and has been modified to incorporate the self-connection of cells. Our network is thus well suited to solve optimization problems where the initial state of the system represents the data constituting the problem. The performance of the network is presented using simulations and it is demonstrated that the signal-to-noise ratio can be improved given constraints on the solid angle of the detector and the correct identification of the photons

  17. Henry constants in polymer solutions with the van der Waals equation of state

    DEFF Research Database (Denmark)

    Bithas, Sotiris; Kalospiros, Nikolaos; Kontogeorgis, Georgios

    1996-01-01

    parameter is satisfactory, with typical errors within the experimental uncertainty and comparable to those with the more complex Perturbed Hard Chain Theory-based equations of state with the same number of adjustable parameters. A predictive scheme for calculating Henry constants is also presented, which...... is a corresponding-states correlation for a dimensionless Henry constant defined based on the van der Waals equation of state. Satisfactory results-often close to the ones from the one-parameter correlation-are obtained for all systems investigated in this work. Compared with literature models that have been applied...

  18. Copper-Mediated Reactions of Nitriles with Nitromethanes: Aza-Henry Reactions and Nitrile Hydrations.

    Science.gov (United States)

    Kuwabara, Jun; Sawada, Yoshiharu; Yoshimatsu, Mitsuhiro

    2018-02-16

    In this study, the first aza-Henry reaction of nitriles with nitromethane in a CuI/Cs 2 CO 3 /DBU system is described. The process was conveniently and directly used for the synthesis of β-aminonitroalkenes 2a-x and tolerated aryl-, alkyl-, hetaryl-, alkenyl-, and alkynylnitriles. The resulting aminonitroalkenes 2 could be successfully transformed to the corresponding 2-nitroacetophenones, 2-amino-1-halonitroalkenes, 2-alkylaminonitroalkenes, or 3-nitropyridines. In the presence of H 2 O, the aza-Henry reaction turned the reaction path to the nitrile hydration to exclusively yield the amides 3a-s.

  19. Taxing junk food: applying the logic of the Henry tax review to food.

    Science.gov (United States)

    Bond, Molly E; Williams, Michael J; Crammond, Brad; Loff, Bebe

    2010-10-18

    The recent review of taxation in Australia - the Henry tax review - has recommended that the federal government increase the taxes already levied on tobacco and alcohol. Tobacco and alcohol taxes are put forward as the best way of reducing the social harms caused by the use and misuse of these substances. Junk foods have the same pattern of misuse and the same social costs as tobacco and alcohol. The Henry tax review rejects the idea of taxing fatty foods, and to date the government has not implemented a tax on junk food. We propose that a tax on junk food be implemented as a tool to reduce consumption and address the obesity epidemic.

  20. M. Pirgerou on D. Izzo and C. Martinez’s Revisionary Interventions into Henry James

    Directory of Open Access Journals (Sweden)

    2009-07-01

    Full Text Available Donatella Izzo and Carlo Martinez. Revisionary Interventions Into Henry James. Eds. Napoli, 2008. Revisionary Interventions into Henry James is a compilation of a series of papers presented at a colloquium which took place at Università Orientale in Naples, Italy, on October 27, 2006. In her introduction to the volume, Donatella Izzo acknowledges the “rather blatant plagiarism” (7 which lent the book its title.  The borrowing, of course, refers to Donald Pease’s landmark Revisionary Interve...

  1. 78 FR 34428 - Missouri Central Railroad Company-Abandonment Exemption-in Cass, Henry, Johnson, and Pettis...

    Science.gov (United States)

    2013-06-07

    ... No. AB 1070; (Sub-No. 1X)] Missouri Central Railroad Company--Abandonment Exemption--in Cass, Henry, Johnson, and Pettis Counties, MO; Central Midland Railway Company--Discontinuance of Service Exemption--in Cass, Henry, Johnson, and Pettis Counties, MO Missouri Central Railroad Company (MCRR) and Central...

  2. Henri Fayol’un Yönetim Düşüncesi Üzerine Notlar(Notes on Managerial Thought of Henry Fayol)

    OpenAIRE

    Ramazan ŞENGÜL

    2007-01-01

    Henri Fayol, developed a managerial approach which is a perfect guide for both private and public sectors through focusing systematically upon managerial process. A major advantage of Fayol in creating a general managerial doctrine was his pratician side. His managerial thought which was developed in the early 20th century lasted up to our times. The distinguished characteristic of Fayol’s thought was studying the administrative reality through separating it into its functions, in that it hel...

  3. Bd0-bar Bd0 mixing and the prediction of the top-quark mass in an independent particle potential model

    International Nuclear Information System (INIS)

    Barik, N.; Das, P.; Panda, A.R.; Roy, K.C.

    1993-01-01

    Considering B d 0 -bar B d 0 mixing in a potential model of independent quarks by taking the effective interaction Hamiltonian of the standard Salam-Weinberg-Glashow model and subsequently diagonalizing the corresponding mass matrix with respect to B d 0 and bar B d 0 states, we obtain an expression for the mass difference ΔM Bd 0 in terms of the t-quark mass m t . Using the recent observation of the mixing parameter x d =0.72±0.15 by the ARGUS Collaboration, we predict the lower bound on the top-quark mass as m t ≥149 GeV. Further, a consideration of experimental mass difference ΔM Bd 0 =(4.0±0.8)x10 -13 GeV also leads to m t =167 -17 +16 GeV which is in agreement with the recent experimental bound as well as other theoretical predictions. However, such a prediction of m t that utilizes the experimental value of the CKM matrix element |V td | may not appear convincing in view of the large uncertainties in the measurement of |V td | so far reported. Therefore using the range of m t values within its bounds predicted from other independent works, we make a reasonable estimation of |V td |

  4. Theoretical Insight of Physical Adsorption for a Single Component Adsorbent + Adsorbate System: II. The Henry Region

    KAUST Repository

    Chakraborty, Anutosh; Saha, Bidyut Baran; Ng, Kim Choon; Koyama, Shigeru; Srinivasan, Kandadai

    2009-01-01

    evaluated and compared with experimental data. It is found that the adsorbents with higher specific surface areas tend to possess lower heat of adsorption (ΔH°) at the Henry regime. In this paper, we have established the definitive relation between Ai and ΔH

  5. Paul Henry Latimer (1925-2011): discoverer of selective scattering in photosynthetic systems.

    Science.gov (United States)

    Latimer, Margaret Gwyn; Bannister, Thomas T; Govindjee

    2017-10-01

    We provide here a brief tribute to Paul Henry Latimer (November 25, 1925 to October 1, 2011), a dedicated biological physicist, discoverer of selective scattering in biological systems, a wonderful teacher, husband, and father. We provide here a glimpse of his personal and professional life, including reminiscences from F. Dudley Bryant, Dan A. Cross, Bobby E. Pyle, Bryan L. Seiber, and Bruce A. Seiber.

  6. Visualizing the Life and Legacy of Henry VIII: Guiding Students with Eight Types of Graphic Organizers

    Science.gov (United States)

    Gallavan, Nancy P.; Kottler, Ellen

    2010-01-01

    Delving into the life and legacy of Henry VIII is both complex and captivating. People seem compelled to learn more abut his critical contributions and controversial conduct that range from the significant to the scandalous. Reflecting on the history of the world would be incomplete without investigating the events and escapades associated with…

  7. Henri Wallon's Theory of Early Child Development: The Role of Emotions.

    Science.gov (United States)

    Van der Veer, Rene

    1996-01-01

    Discusses the stage theory of early child development of French theorist Henri Wallon. Describes Wallon's efforts (in contrast to contemporary Piaget) to describe emotional development and the role emotions play in establishing the child-caregiver bond. Argues that Wallon's theory is unique in its focus, influenced theorists such as Vygotsky, and…

  8. The Heuristic Method, Precursor of Guided Inquiry: Henry Armstrong and British Girls' Schools, 1890-1920

    Science.gov (United States)

    Rayner-Canham, Geoff; Rayner-Canham, Marelene

    2015-01-01

    Though guided-inquiry learning, discovery learning, student-centered learning, and problem-based learning are commonly believed to be recent new approaches to the teaching of chemistry, in fact, the concept dates back to the late 19th century. Here, we will show that it was the British chemist, Henry Armstrong, who pioneered this technique,…

  9. The Royal Entries of Henry VI in a London Civic Manuscript

    DEFF Research Database (Denmark)

    Bourassa, Kristin

    2016-01-01

    London Metropolitan Archives, MS Letter Book K, contains descriptions of Henry VI’s royal entries into both Paris (1431) and London (1432). Their placement one after the other in a London Letter Book was likely the work of the city’s common clerk, John Carpenter, who was the author of the descrip...

  10. 76 FR 63906 - Henry Gordy International, Inc., Provisional Acceptance of a Settlement Agreement and Order

    Science.gov (United States)

    2011-10-14

    ... International, Inc., containing a civil penalty of $1,100,000.00. DATES: Any interested person may ask the... report of a death involving a Target Set on or about May 1, 2006, after an 8-year-old boy choked on a dart and died on March 9, 2006. 8. In response to the death reported on or about May 1, 2006, Henry...

  11. The Snake Charmer(ess intermedia dialogue between Henri Rousseau's Painting and Sylvia Plath's poetry

    Directory of Open Access Journals (Sweden)

    Milovanov Dajana

    2017-01-01

    Full Text Available The paper examines possible interpretations of poetry and poetic image analysing the dialogue between the arts of literature and painting. The paper studies the poet Sylvia Plath's referencing Henri Rousseau's painting The Snake Charmer in her poem 'Snakecharmer'. What is analysed is the creative superstructure based upon nonliterary reference, as well as the visual elements attained through two diverse artistic media.

  12. Ernest Henry Starling: the history of cardiovascular endocrinology and the continuous need for developing animal models

    DEFF Research Database (Denmark)

    Henriksen, Jens Henrik Sahl

    2014-01-01

    The English physiologist, Ernest Henry Starling (1866–1927) (Fig. 1) in 1896, provided a quantitative explanation of the transcapillary transport of fluid. Six years later, he discovered the first hormone and introduced the concept of hormones in 1905, and at the time of the First World War, he f......’s achievements in cardiovascular physiology and endocrinology....

  13. W.E. Henry Symposium Compendium, Lawrence Berkeley National Laboratory, September 19, 1997

    Science.gov (United States)

    1997-09-19

    Society • Philosophical Society of Washington • Washington Academy of Sciences • New York Academy of Sciences • Institut International du Froid ...Powered Magnets" Reports of NRL Progress, Nov. 1958. 29. Henry, Warren E. "Aimantation dans les champs forts et approche a la saturation absolue du

  14. Enter the Madcap Prince of Wales: Students Directing "Henry IV, Part I."

    Science.gov (United States)

    Earthman, Elise Ann

    1993-01-01

    Argues that William Shakespeare's "Henry IV, Part I" is an appropriate and useful text for secondary English classrooms. Shows how the play lends itself to performance-based instruction. Outlines ways of accomplishing student engagement, using film versions, and assigning written work. (HB)

  15. Community Arts Programs: Cohesion and Difference Case Studies. Henry Street Settlement and El Museo del Barrio

    Science.gov (United States)

    Kiebert-Gruen, Cathleen

    2009-01-01

    A comparative case study of two cultural institutions, Henry Street Settlement and El Museo del Barrio, founded almost eighty years apart, were involved in social justice causes and community arts. Although both of these institutions participated in the political activism of their time, they also demonstrated an important adaptability. They were…

  16. Pornografia e transgressão na obra literária de Henry Miller

    Directory of Open Access Journals (Sweden)

    Raquel Catunda Pereira

    2016-07-01

    Full Text Available The North American writer Henry Miller was marginalized by literary critics since the first publications of his works in the 40s. Accused of being a pornographic text, the book Tropic of Cancer (1934 was forbidden in many countries. This article aims to analyze the obscene in Henry Miller’s work to prove that, beyond the erotic intention, Miller’s books are an expression of freedom and rejection of moral standards. In order to achieve our goal, we will use as theoretical basis the articles Criticismo e sexualidade: uma leitura de Tropico of Capricorn de Henry Miller, by Flávia Andréa Rodrigues Benfatt, and Literatura marginal americana: do épico confessional ao niilismo erótico, by Lainister de Oliveira. The texts mentioned above grant us the argumentation necessary to the analysis of pornographic discourse in Henry Miller’s literary works as the author’s aesthetics choice of taking himself as a transgressor in a decadent society.

  17. Henry Evelyn Bliss--The Other Immortal, or a Prophet without Honour?

    Science.gov (United States)

    Broughton, Vanda

    2008-01-01

    The paper takes a retrospective look at the work of Henry Evelyn Bliss, classificationist theorist and author of the "Bibliographic Classification". Major features of his writings and philosophy are examined and evaluated for the originality of their contribution to the corpus of knowledge in the discipline. Reactions to Bliss's work are analysed,…

  18. Mounting a Curricular Revolution: An Interview with Henry Louis Gates, Jr.

    Science.gov (United States)

    von Zastrow, Claus

    2009-01-01

    This article presents an interview with Henry Louis Gates, Jr., Harvard professor and cultural critic who has captured 25 million viewers with his PBS documentary series, African American Lives (WNET). Using genealogical research and DNA science, Gates traces the family history of 19 famous African Americans. What results is a rich and moving…

  19. The 'Overly-Broad' Selden Patent, Henry Ford and Development in the Early US Automobile Industry

    DEFF Research Database (Denmark)

    Howells, John; Katznelson, Ron D

    of the Selden patent claims. We use new primary sources to show how Henry Ford and others engaged in what today is called “Freedom to Operate” patent analysis when it most mattered commercially. We show that Ford correctly anticipated that a future court adjudication of the Selden patent claims would...

  20. Fin-de-Siecle Advances in Neuroeducation: Henry Herbert Donaldson and Reuben Post Halleck

    Science.gov (United States)

    Theodoridou, Zoe D.; Triarhou, Lazaros C.

    2009-01-01

    This article focuses on two early attempts at bridging neuroscience and education, made by Henry Herbert Donaldson (1857-1938), a neurologist, and Reuben Post Halleck (1859-1936), an educator. Their works, respectively entitled "The Growth of the Brain: A Study of the Nervous System in Relation to Education" (1895) and "The Education of the…

  1. DEFB1 polymorphisms and salivary hBD-1 concentration in Oral Lichen Planus patients and healthy subjects.

    Science.gov (United States)

    Polesello, Vania; Zupin, Luisa; Di Lenarda, Roberto; Biasotto, Matteo; Pozzato, Gabriele; Ottaviani, Giulia; Gobbo, Margherita; Crovella, Sergio; Segat, Ludovica

    2017-01-01

    The aetiology of Oral Lichen Planus (OLP), a chronic inflammatory disease of oral mucosa, is not yet well understood. Since innate immunity may be hypothesized as involved in the susceptibility to OLP, we studied human beta defensin 1 (hBD-1) an antimicrobial peptide constitutively expressed in the saliva, looking at functional genetic variants possibly able to diminish hBD-1 production an consequently conferring major susceptibility to OLP. We analysed three DEFB1 polymorphisms at 5' UTR, -52G>A (rs1799946), -44C>G (rs1800972), -20G>A (rs11362) and two DEFB1 polymorphisms at 3'UTR, c*5G>A (rs1047031), c*87A>G (rs1800971), with the aim of correlating these genetic variants and hBD-1 salivary level in a group of OLP patients and in healthy subjects. We also evaluated hBD-1 salivary concentrations, using ELISA, in OLP and healthy controls. We compared hBD-1 concentrations in OLP and healthy subjects: hBD-1 concentration was significantly higher in OLP patients respect to control. When considering the correlation between DEFB1 polymorphisms genotypes and hBD-1 expression levels, significant results were obtained for SNPs -52G>A (p=0.03 both in OLP patients and healthy individuals) and -44C>G (p=0.02 in OLP patients). hBD-1 production was different between OLP and healthy subjects (not age-matched with OLP). DEFB1 gene polymorphisms, -52G>A and -44C>G, correlated with hBD-1 salivary concentrations. Copyright © 2016 Elsevier Ltd. All rights reserved.

  2. High Velocity Spectroscopic Binary Orbits from Photoelectric Radial Velocities: BD+20 5152, a Possible Triple System

    Directory of Open Access Journals (Sweden)

    Sperauskas J.

    2010-12-01

    Full Text Available The spectroscopic orbit of a high proper motion star, BD+20 5152, is calculated from 34 CORAVEL-type radial velocity measurements. The star has a slightly eccentric orbit with a period of 5.70613 d, half-amplitude of 47.7 km/s and eccentricity of 0.049. The center-of-mass velocity of the system is -24.3 km/s. BD+20 5152 seems to be a triple system consisting of a G8 dwarf as a primary component and of two K6-M0 dwarfs as secondary and tertiary components. This model is based on the analysis of its UBVRI and JHK magnitudes. According to the SuperWASP photometry, spots on the surface of the primary are suspected. The excessive brightness in the Galex FUV and NUV magnitudes and a non-zero eccentricity suggest the age of this system to be less than 1 Gyr.

  3. TRAC-BD1: transient reactor analysis code for boiling-water systems

    International Nuclear Information System (INIS)

    Spore, J.W.; Weaver, W.L.; Shumway, R.W.; Giles, M.M.; Phillips, R.E.; Mohr, C.M.; Singer, G.L.; Aguilar, F.; Fischer, S.R.

    1981-01-01

    The Boiling Water Reactor (BWR) version of the Transient Reactor Analysis Code (TRAC) is being developed at the Idaho National Engineering Laboratory (INEL) to provide an advanced best-estimate predictive capability for the analysis of postulated accidents in BWRs. The TRAC-BD1 program provides the Loss of Coolant Accident (LOCA) analysis capability for BWRs and for many BWR related thermal hydraulic experimental facilities. This code features a three-dimensional treatment of the BWR pressure vessel; a detailed model of a BWR fuel bundle including multirod, multibundle, radiation heat transfer, leakage path modeling capability, flow-regime-dependent constitutive equation treatment, reflood tracking capability for both falling films and bottom flood quench fronts, and consistent treatment of the entire accident sequence. The BWR component models in TRAC-BD1 are described and comparisons with data presented. Application of the code to a BWR6 LOCA is also presented

  4. Assessment of TRAC-BD1/MOD1 using FIST data

    International Nuclear Information System (INIS)

    Jo, J.H.; Connell, H.R.

    1985-01-01

    This report is concerned with the assessment of the TRAC-BD1/MOD1 Code, developed at Idaho National Engineering Laboratory. The assessment was conducted using data from the FIST (Full Integral Simulation Test) facility, which is a BWR safety test facility which was built to investigate small break LOCA and operational transients in BWR's and to complement earlier large break LOCA test results from TLTA (Two-Loop Test Apparatus). 21 figs

  5. One-electron oxidation of BD84, an ellipticine antitumor derivative

    International Nuclear Information System (INIS)

    Sekaki, A.; Gardes-Albert, M.; Houee-Levin, C.; Ferradini, C.; Rivalle, C.; Bisagni, E.; Hickel, B.

    1991-01-01

    The one-electron oxidation of BD84, an ellipticine-related drug, has been studied by pulse radiolysis using OH· radicals as oxidizing agents. In the absence of oxygen, R· radicals are formed. They disappear by recombination. In the presence of oxygen, R· radicals react with O 2 to give peroxy radicals RO 2 ·, which decay by a second-order process. These results are compared to those obtained for other ellipticine derivatives [fr

  6. Clinical and analytical performance of the BD Onclarity™ HPV assay for detection of CIN2+ lesions on SurePath samples

    DEFF Research Database (Denmark)

    Ejegod, Ditte Møller; Junge, Jette; Franzmann, Maria

    2016-01-01

    BACKGROUND: The novel BD Onclarity(TM) HPV assay (Onclarity) on the BD Viper™ LT system (BD Diagnostics, Sparks, MD), detects E6/E7 DNA from 13 high-risk HPV genotypes and HPV66. We compared the analytical and clinical performance of the Onclarity Assay to that of Hybrid Capture 2 and LINEAR ARRAY...

  7. 17 CFR 249.618 - Form BD-Y2K, information required of broker-dealers pursuant to section 17 of the Securities...

    Science.gov (United States)

    2010-04-01

    ... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Form BD-Y2K, information... Exchange Members, Brokers, and Dealers § 249.618 Form BD-Y2K, information required of broker-dealers... FR 37674, July 13, 1998] Editorial Note: For Federal Register citations affecting Form BD-Y2K, see...

  8. Photochemistry of U(BH/sub 4/)/sub 4/ and U(BD/sub 4/)/sub 4/

    Energy Technology Data Exchange (ETDEWEB)

    Paine, R T; Schonberg, P R; Light, R W [New Mexico Univ., Albuquerque (USA). Dept. of Chemistry; Danen, W C; Freund, S M

    1979-01-01

    U(BH/sub 4/)/sub 4/ and U(BD/sub 4/)/sub 4/ are observed to undergo complex degradation reactions promoted by broadband UV radiation. The primary products of these reactions appear to be U(BH/sub 4/)/sub 3/, B/sub 2/H/sub 6/, H/sub 2/, U(BD/sub 4/)/sub 3/, B/sub 2/D/sub 6/ and D/sub 2/. Further, U(BD/sub 4/)/sub 4/ undergoes a related decomposition reaction under the influence of CO/sub 2/ laser irradiation at 924.97 cm/sup -1/.

  9. Photometric, Spectroscopic, and X-ray Analysis of the Cool Algol BD+05 706

    Science.gov (United States)

    Torres, G.; Mader, J.; Marschall, L. A.; Neuhaeuser, R.; Duffy, A. S.

    2000-12-01

    BD+05 706 is an example of a rare class of a dozen or so interacting binaries called ``cool Algols", in which both components of the system are late-type stars. By contrast, the ``classical Algols" are systems in which the star transfering mass is of late spectral type, but the mass gainer is much hotter. BD+05 706 was shown previously to be eclipsing (Marschall, Torres & Neuhaeuser 1998, BAAS, 30, 835). In this paper we report our complete analysis of BVRI light curves for the system obtained at Gettysburg College Observatory, together with spectroscopy from the Harvard-Smithsonian Center for Astrophysics reported previously (Torres, Neuhaeuser & Wichmann 1998, AJ, 115, 2028), and X-ray observations obtained with the ROSAT satellite. Our light curve analysis indicates the presence of spots, most likely on the more massive, active component (primary), which change from season to season. Our results confirm the semi-detached nature of the system, and combined with the spectroscopy they have allowed us to obtain the most precise absolute masses and radii for any object of this class. Our X-ray light curve for BD+05 706 shows the primary eclipse clearly, but no sign of a secondary eclipse, confirming that the primary is the active star. Strong X-ray flares are also visible.

  10. Mixing and CP violation in the Bd and Bs systems at ATLAS

    CERN Document Server

    AUTHOR|(INSPIRE)INSPIRE-00229256; The ATLAS collaboration

    2016-01-01

    This note includes a measurement of the $B^0_s$ decay parameters in the $ B_s \\rightarrow J/\\psi$ channel and a measurement of the $B_d$ meson using the statistics collected by the ATLAS experiment in Run I of the LHC. The first result presents the measurement of the $CP$-violating phase $\\phi_s$, the decay width $\\Gamma_s$ and the width difference between the mass eigenstates $\\Delta \\Gamma_s$. The second result presents the measurement of the width difference $\\Delta \\Gamma_d$, which is extracted from the measurement of the lifetime dependence of $B_d \\to J/\\psi K_S$ and $B_d \\to J/\\psi K^{*0}$ decays. The obtained results are $\\phi_s = −0.098 \\pm 0.084 (\\textrm{stat.}) \\pm 0.040 (\\textrm{syst.})$ rad. and $\\Delta \\Gamma_d / \\Gamma_d = (-0.1 \\pm 1.1 (\\textrm{stat.}) \\pm 0.9 (\\textrm{syst.}))\\times 10^{-2}$.

  11. Dextran synthesized by Leuconostoc mesenteroides BD1710 in tomato juice supplemented with sucrose.

    Science.gov (United States)

    Han, Jin; Hang, Feng; Guo, Benheng; Liu, Zhenmin; You, Chunpin; Wu, Zhengjun

    2014-11-04

    The characteristics of the growth of Leuconostoc mesenteroides BD1710 and the synthesis of dextran in tomato juice supplemented with 15% sucrose were assayed. L. mesenteroides BD1710 could synthesize approximately 32 g L(-1) dextran in the tomato-juice-sucrose medium when cultured at 28 °C for 48 h, which was on the same level as the dextran yield in a chemically defined medium. The viscosity of the cultured tomato-juice-sucrose medium with various dextran contents was also measured. The results of the monosaccharide composition, molecular-weight distribution, Fourier transform infrared spectra (FTIR) and nuclear magnetic resonance spectra (NMR) showed that the polysaccharide synthesized by L. mesenteroides BD1710 in the tomato-juice-sucrose medium was dextran with a peak molecular weight of 6.35 × 10(5)Da, a linear backbone composed of consecutive α-(1 → 6)-linked d-glucopyranosyl units and approximately 6% α-(1 → 3) branches. Copyright © 2014 Elsevier Ltd. All rights reserved.

  12. Fixed Combination Aerosol Foam Calcipotriene 0.005% (Cal) Plus Betamethasone Dipropionate 0.064% (BD) is More Efficacious than Cal or BD Aerosol Foam Alone for Psoriasis Vulgaris

    Science.gov (United States)

    Tyring, Stephen; Bukhalo, Michael; Alonso-Llamazares, Javier; Olesen, Martin; Lowson, David; Yamauchi, Paul

    2016-01-01

    Objective: To evaluate the efficacy of fixed combination aerosol foam calcipotriene 0.005% (Cal) plus betamethasone dipropionate 0.064% (BD). Design: Patients were randomized (100:101:101) to receive Cal/BD foam, Cal foam, or BD foam once daily for four weeks. Setting: Twenty-eight United States centers. Participants: 302 patients (≥18 years) with Psoriasis vulgaris (plaque Psoriasis; ≥mild disease severity by physicians global assessment). Measurements: Treatment success of the body (“clear”/”almost clear” from baseline moderate/severe disease; “clear” from baseline mild disease). Involved scalp treatment success was an additional endpoint. Results: Most patients (76%) had moderate Psoriasis of the body (66% for scalp). At Week 4, 45 percent of Cal/BD foam patients achieved treatment success, significantly more than Cal foam (14.9%; OR 4.34 [95%CI 2.16,8.72] Pfoam (30.7%; 1.81 [1.00,3.26] P=0.047). Fifty-three percent of Cal/BD foam patients achieved treatment success of the scalp, significantly greater than Cal foam (35.6%; 1.91 [1.09,3.35] P=0.021), but not BD foam (47.5%; 1.24 [0.71,2.16] P=0.45). Mean modified Psoriasis area and severity index (population baseline 7.6) improved in all groups, with statistically significant differences in Week 4 Cal/BD foam score (2.37) versus Cal foam (4.39; mean difference -2.03 [-2.63][-1.43] Pfoam (3.37; -1.19 [-1.80][-0.59] Pfoam was significantly more effective than Cal foam and BD foam in providing treatment success at Week 4 and effective on involved scalp. Trial registration: NCT01536938. PMID:27313822

  13. Validity and reliability of the Brief version of Quality of Life in Bipolar Disorder" (Bref QoL.BD) among Chinese bipolar patients.

    Science.gov (United States)

    Xiao, Lin; Gao, Yulin; Zhang, Lili; Chen, Peiyun; Sun, Xiaojia; Tang, Siyuan

    2016-03-15

    Previous literatures on quality of life (QoL) in bipolar disorder (BD) strongly suggested that a disease-specific QoL measure for patients with BD should be developed to evaluate QoL more specifically and reliably. To our knowledge, "Quality of Life in Bipolar Disorder" (QoL.BD) is the first and only questionnaire produced to specifically measure QoL in people with BD. In China, there is no disease-targeted measure available to specifically measure QoL in Chinese patients with BD. The aim of the study is to revise and validate the brief version of the QoL.BD (Bref QoL.BD ) into Chinese version. All the items of the Bref QoL.BD was translated into Chinese language, using the Brislin translation mode. The questionnaire was administered to a total sample of 231 subjects, including 101 BD patients and 130 healthy controls, to test the psychometric properties of Bref QoL.BD (e.g. internal consistency, retest reliability, content validity, item analysis, confirmatory factor analysis, criterion validity, convergent validity, discriminative validity and feasibility). The Chinese version of the Bref QoL.BD had very high internal consistency (Cronbach's alpha=0.815) and retest reliability (intraclass correlation coefficient (ICC )=0.808). Confirmatory factor analysis (CFA) validated the original one-factor structure. The direction and magnitude of correlations with 36-item Short-Form Health Survey (SF-36; rs= 0.313, Psize from only one tertiary care center. And BD patients enrolled were euthymic, excluding the acute BD patients. The Chinese version of the Bref QoL.BD is a feasible, reliable and valid tool for the assessment of QoL for Chinese BD patients. Copyright © 2015 Elsevier B.V. All rights reserved.

  14. SUBSTELLAR-MASS COMPANIONS TO THE K-DWARF BD+14 4559 AND THE K-GIANTS HD 240210 AND BD+20 2457

    International Nuclear Information System (INIS)

    Niedzielski, A.; Nowak, G.; Adamow, M.; Wolszczan, A.

    2009-01-01

    We present the discovery of substellar-mass companions to three stars by the ongoing Penn State-Torun Planet Search conducted with the 9.2 m Hobby-Eberly Telescope. The K2-dwarf, BD+14 4559, has a 1.5 M J minimum mass companion with the orbital period of 269 days and shows a non-linear, long-term radial velocity (RV) trend, which indicates a possible presence of another planet-mass body in the system. The K3-giant, HD 240210, exhibits RV variations that require modeling with multiple orbits, but the available data are not yet sufficient to do it unambiguously. A tentative, one-planet model calls for a 5.2 M J minimum mass planet in a 502 day orbit around the star. The most massive of the three stars, the K2-giant, BD+20 2457, whose estimated mass is 2.8 ± 1.5 M sun , has two companions with the respective minimum masses of 21.4 M J and 12.5 M J and orbital periods of 380 and 622 days. Depending on the unknown inclinations of the orbits, the currently very uncertain mass of the star, and the dynamical properties of the system, it may represent the first detection of two brown dwarf-mass companions orbiting a giant. The existence of such objects will have consequences for the interpretation of the so-called brown dwarf desert known to exist in the case of solar-mass stars.

  15. Effect of chloride substitution on the order–disorder transition in NaBH4 and Na11BD4

    International Nuclear Information System (INIS)

    Olsen, Jørn Eirik; Karen, Pavel; Sørby, Magnus H.; Hauback, Bjørn C.

    2014-01-01

    Graphical abstract: Interactions that order the BD 4 - tetrahedra below the order–disorder transition became increasingly frustrated by the solute in the Na( 11 BD 4 ) 1−x Cl x solid solutions, and the order disappears at x = 0.158. Highlights: • The order–disorder transition temperature for Na(BH 4 ) 1−x Cl x and Na( 11 BD 4 ) 1−x Cl x is highly dependent on the Cl-content, x. • The transition is characterized by DSC for Na( 11 BD 4 ) 1−x Cl x for x = 0, 0.10 and 0.15. • No transition is observed for x ⩾ 0.20 on cooling to 8 K. • The crystal structures are reported for Na 11 BD 4 at room temperature and 8 K and Na( 11 BD 4 ) 1−x Cl x (x = 0.10, 0.15, 0.20 and 0.25) at 8 K from powder neutron diffraction. -- Abstract: Phase transition associated with anion disordering over two orientations in Na 11 BD 4 (NaBH 4 ) and its solid solutions with NaCl, Na( 11 BD 4 ) 1−x Cl x , is investigated with powder diffraction (neutron and synchrotron radiation), differential scanning calorimetry and Raman spectroscopy. Upon heating, the transition temperature extrapolated to zero rate of heating is 192.2 K for Na 11 BD 4 , ΔS = 4.41 J/mol K, hysteresis 1.7 K and the volume increase 0.43%. Thermal parameters of the transition in Na( 11 BD 4 ) 1−x Cl x follow a colligative-property model of an ideal solution, with x = 0.158(1) as the critical concentration at which the ordering interactions and the transition itself are eliminated. On approaching this limit, the tetragonal distortion of the ordered structure decreases somewhat towards the cubic average, and this is associated with a partial disorder of the tetrahedral anions seen by diffraction methods. In fact, a 3% disorder is already present in the pure solvent of the solid solution (Na 11 BD 4 ) at 8 K

  16. Henry's Constants of Persistent Organic Pollutants by a Group-Contribution Method Based on Scaled-Particle Theory.

    Science.gov (United States)

    Razdan, Neil K; Koshy, David M; Prausnitz, John M

    2017-11-07

    A group-contribution method based on scaled-particle theory was developed to predict Henry's constants for six families of persistent organic pollutants: polychlorinated benzenes, polychlorinated biphenyls, polychlorinated dibenzodioxins, polychlorinated dibenzofurans, polychlorinated naphthalenes, and polybrominated diphenyl ethers. The group-contribution model uses limited experimental data to obtain group-interaction parameters for an easy-to-use method to predict Henry's constants for systems where reliable experimental data are scarce. By using group-interaction parameters obtained from data reduction, scaled-particle theory gives the partial molar Gibbs energy of dissolution, Δg̅ 2 , allowing calculation of Henry's constant, H 2 , for more than 700 organic pollutants. The average deviation between predicted values of log H 2 and experiment is 4%. Application of an approximate van't Hoff equation gives the temperature dependence of Henry's constants for polychlorinated biphenyls, polychlorinated naphthalenes, and polybrominated diphenyl ethers in the environmentally relevant range 0-40 °C.

  17. [Crusading and Chronicle Writing on the Medieval Baltic Frontier: A Companion to the Chronicle of Henry of Livonia] / Michael Amundsen

    Index Scriptorium Estoniae

    Amundsen, Michael

    2012-01-01

    Arvustus: Crusading and chronicle writing on the medieval Baltic frontier : a companion to the Chronicle of Henry of Livonia / edited by Marek Tamm, Linda Kaljundi, Carsten Selch Jensen. Farnham : Ashgate, 2011

  18. The Henry-Saltwater Intrusion Benchmark – Alternatives in Multiphysics Formulations and Solution Strategies

    Directory of Open Access Journals (Sweden)

    E Holzbecher

    2016-03-01

    Full Text Available In a classical paper Henry set up a conceptual model for simulating saltwater intrusion into coastal aquifers. Up to now the problem has been taken up by software developers and modellers as a benchmark for codes simulating coupled flow and transport in porous media. The Henry test case has been treated using different numerical methods based on various formulations of differential equations. We compare several of these approaches using multiphysics software. We model the problem using Finite Elements, utilizing the primitive variables and the streamfunction approach, both with and without using the Oberbeck-Boussinesq assumption. We compare directly coupled solvers with segregated solver strategies. Changing finite element orders and mesh refinement, we find that models based on the streamfunction converge 2-4 times faster than runs based on primitive variables. Concerning the solution strategy, we find an advantage of Picard iterations compared to monolithic Newton iterations.

  19. DNA-Catalyzed Henry Reaction in Pure Water and the Striking Influence of Organic Buffer Systems

    Directory of Open Access Journals (Sweden)

    Marleen Häring

    2015-03-01

    Full Text Available In this manuscript we report a critical evaluation of the ability of natural DNA to mediate the nitroaldol (Henry reaction at physiological temperature in pure water. Under these conditions, no background reaction took place (i.e., control experiment without DNA. Both heteroaromatic aldehydes (e.g., 2-pyridinecarboxaldehyde and aromatic aldehydes bearing strong or moderate electron-withdrawing groups reacted satisfactorily with nitromethane obeying first order kinetics and affording the corresponding β-nitroalcohols in good yields within 24 h. In contrast, aliphatic aldehydes and aromatic aldehydes having electron-donating groups either did not react or were poorly converted. Moreover, we discovered that a number of metal-free organic buffers efficiently promote the Henry reaction when they were used as reaction media without adding external catalysts. This constitutes an important observation because the influence of organic buffers in chemical processes has been traditionally underestimated.

  20. A French description of German psychology laboratories in 1893 by Victor Henri, a collaborator of Binet.

    Science.gov (United States)

    Nicolas, Serge; Barnes, Marissa E; Murray, David J

    2015-05-01

    There is a rich tradition of writings about the foundation of psychology laboratories, particularly in the United States but also in France. Various documents exist concerning former German laboratories in American and French literature. But the most interesting French paper was certainly written by a young psychologist named Victor Henri (1872-1940) who was a close collaborator of Alfred Binet (1857-1911) in the 1890s. Visiting various psychology laboratories, he wrote, in 1893, a clear description of the laboratories of Wundt, G. E. Müller, Martius and Ebbinghaus. An English translation is given of Henri's paper and the historical importance of his contribution is here expounded by contrasting the German and French psychologies of the time.

  1. "Audacity or Precision": The Paradoxes of Henri Villat's Fluid Mechanics in Interwar France

    OpenAIRE

    Aubin , David

    2010-01-01

    In Interwar France, Henri Villat became the true leader of theoretical researches on fluid mechanics. Most of his original work was done before the First World War; it was highly theoretical and its applicability was questioned. After having organized the first post-WWI International Congress of Mathematicians in 1920, Villat became the editor of the famous Journal de math\\'ematiques pure et appliqu\\'es and the director of the influential book series "M\\'emorial des sciences math\\'ematiques."...

  2. Henry Fayol’s 14 Principles of Management: Implications for Libraries and Information Centres

    OpenAIRE

    Uzuegbu, C. P.; Nnadozie, C. O.

    2015-01-01

    This paper focuses generally on the ‘fourteen principles of management’ by Henri Fayol. However, it specifically analyses their application to and implications for libraries and information centres. An extensive review of published works on management generally, and library management in particular, was conducted. This yielded vital insights on the original meaning and later modifications of these principles, as well as their application in the management of various organisation...

  3. Staging Henry Fielding: The Author-Narrator in Tom Jones On Screen

    OpenAIRE

    Løfaldli, Eli

    2017-01-01

    As recent adaptation theory has shown, classic-novel adaptation typically sets issues connected to authorship and literal and figurative ownership into play. This key feature of such adaptations is also central to the screen versions of Henry Fielding’s Tom Jones (1749). In much of Fielding’s fiction, the narrator, typically understood as an embodiment of Fielding himself, is a particularly prominent presence. The author-narrator in Tom Jones is no exception: not only is his presence strongly...

  4. VIDEO: Dr. Henry Rodriguez - Proteogenomics in Cancer Medicine | Office of Cancer Clinical Proteomics Research

    Science.gov (United States)

    Dr. Henry Rodriguez, director of the Office of Cancer Clinical Proteomics Research (OCCPR) at NCI, speaks with ecancer television at WIN 2017 about the translation of the proteins expressed in a patient's tumor into a map for druggable targets. By combining genomic and proteomic information (proteogenomics), leading scientists are gaining new insights into ways to detect and treat cancer due to a more complete and unified understanding of complex biological processes.

  5. Henry Agard Wallace, the Iowa Corn Yield Tests, and the Adoption of Hybrid Corn

    OpenAIRE

    Richard C. Sutch

    2008-01-01

    This research report makes the following claims: 1] There was not an unambiguous economic advantage of hybrid corn over the open-pollinated varieties in 1936. 2] The early adoption of hybrid corn before 1937 can be better explained by a sustained propaganda campaign conducted by the U.S. Department of Agriculture at the direction of the Secretary of Agriculture, Henry Agard Wallace. The Department's campaign echoed that of the commercial seed companies. The most prominent hybrid seed company,...

  6. Review: Henry E. Brady & David Collier (Hrsg.) (2004). Rethinking Social Inquiry: Diverse Tools, Shared Standards

    OpenAIRE

    Catón, Matthias

    2006-01-01

    Das Buch Rethinking Social Inquiry, herausgegeben von Henry E. BRADY und David COLLIER, ist eine Antwort auf den Band von KING, KEOHANE und VERBA (1994), in dem versucht wird, Standards der quantitativen Forschung in der qualitativen Forschung einzuführen. Die Autoren des hier rezensierten Buchs kritisieren viele der Vorschläge, da sie argumentieren, dass qualitative Forschung anderer Werkzeuge bedürfe. Trotzdem stimmen sie zu, dass die Grundlagen des Forschungsaufbaus ähnlich sind. Das Buch ...

  7. Review: Henry E. Brady & David Collier (Eds.) (2004). Rethinking Social Inquiry: Diverse Tools, Shared Standards

    OpenAIRE

    Matthias Catón

    2006-01-01

    Das Buch Rethinking Social Inquiry, herausgegeben von Henry E. BRADY und David COLLIER, ist eine Antwort auf den Band von KING, KEOHANE und VERBA (1994), in dem versucht wird, Standards der quantitativen Forschung in der qualitativen Forschung einzuführen. Die Autoren des hier rezensierten Buchs kritisieren viele der Vorschläge, da sie argumentieren, dass qualitative Forschung anderer Werkzeuge bedürfe. Trotzdem stimmen sie zu, dass die Grundlagen des Forschungsaufbaus ähnlich sind. Das Buch ...

  8. Pelecitus helicinus Railliet & Henry, 1910 (Filarioidea, Dirofilariinae and Other Nematode Parasites of Brazilian Birds

    Directory of Open Access Journals (Sweden)

    Oniki Yoshika

    2002-01-01

    Full Text Available We report Pelecitus helicinus Railliet & Henry, 1910 from 13 species of birds of 2 orders and 7 families, collected from the states of São Paulo and Mato Grosso, Brazil. All 13 constitute new host records for this nematode. In addition, we report the first record of Aprocta golvani Diaz-Ungria, 1963 from Brazil and Monasa nigrifrons (Bucconidae, as well as a number of other nematode records from Neotropical birds.

  9. Henri Fayol, théoricien de l’entreprise innovante

    OpenAIRE

    Hatchuel , Armand; Segrestin , Blanche

    2016-01-01

    International audience; Have we correctly read Henri Fayol? His work is still reduced to general principles of administration that seem rigid and trivial. Yet, he has been a great innovative leader that considered scientific research as a major task of the business executive. A new reading of Fayol's masterpiece shows that he introduced sophisticated notions: " the unknown " , " the program of action " , " the advancement " , which meaning was erased by his translators or forgotten. Coming fr...

  10. Henri Fayol. Performativity of his ideas and oblivion of their creator

    OpenAIRE

    Dumez , Hervé

    2018-01-01

    Henri Fayol formulated one of the first theories of management and allows us to see how one of the first scientific approaches of management could or could not perform management practices. Therefore, Fayol is particularly interesting from the point of view of performativity (Callon, 1998, 2007, MacKenzie et al., 2007, Muniesa, 2014). The case is all the richer because it presents the rare characteristic of a direct confrontation between two rival theories, his and Taylor's, at the level of t...

  11. The Bifidobacterium dentium Bd1 genome sequence reflects its genetic adaptation to the human oral cavity.

    Directory of Open Access Journals (Sweden)

    Marco Ventura

    2009-12-01

    Full Text Available Bifidobacteria, one of the relatively dominant components of the human intestinal microbiota, are considered one of the key groups of beneficial intestinal bacteria (probiotic bacteria. However, in addition to health-promoting taxa, the genus Bifidobacterium also includes Bifidobacterium dentium, an opportunistic cariogenic pathogen. The genetic basis for the ability of B. dentium to survive in the oral cavity and contribute to caries development is not understood. The genome of B. dentium Bd1, a strain isolated from dental caries, was sequenced to completion to uncover a single circular 2,636,368 base pair chromosome with 2,143 predicted open reading frames. Annotation of the genome sequence revealed multiple ways in which B. dentium has adapted to the oral environment through specialized nutrient acquisition, defences against antimicrobials, and gene products that increase fitness and competitiveness within the oral niche. B. dentium Bd1 was shown to metabolize a wide variety of carbohydrates, consistent with genome-based predictions, while colonization and persistence factors implicated in tissue adhesion, acid tolerance, and the metabolism of human saliva-derived compounds were also identified. Global transcriptome analysis demonstrated that many of the genes encoding these predicted traits are highly expressed under relevant physiological conditions. This is the first report to identify, through various genomic approaches, specific genetic adaptations of a Bifidobacterium taxon, Bifidobacterium dentium Bd1, to a lifestyle as a cariogenic microorganism in the oral cavity. In silico analysis and comparative genomic hybridization experiments clearly reveal a high level of genome conservation among various B. dentium strains. The data indicate that the genome of this opportunistic cariogen has evolved through a very limited number of horizontal gene acquisition events, highlighting the narrow boundaries that separate commensals from

  12. Overexpression of BdMATE Gene Improves Aluminum Tolerance in Setaria viridis

    Directory of Open Access Journals (Sweden)

    Ana P. Ribeiro

    2017-06-01

    Full Text Available Acidic soils are distributed worldwide, predominantly in tropical and subtropical areas, reaching around 50% of the arable soil. This type of soil strongly reduces crop production, mainly because of the presence of aluminum, which has its solubility increased at low pH levels. A well-known physiological mechanism used by plants to cope with Al stress involves activation of membrane transporters responsible for organic acid anions secretion from the root apex to the rhizosphere, which chelate Al, preventing its absorption by roots. In sorghum, a membrane transporter gene belonging to multidrug and toxic compound extrusion (MATE family was identified and characterized as an aluminum-activated citrate transporter gene responsible for Al tolerance in this crop. Setaria viridis is an emerging model for C4 species and it is an important model to validate some genes for further C4 crops transformation, such as sugarcane, maize, and wheat. In the present work, Setaria viridis was used as a model plant to overexpress a newly identified MATE gene from Brachypodium distachyon (BdMATE, closely related to SbMATE, for aluminum tolerance assays. Transgenic S. viridis plants overexpressing a BdMATE presented an improved Al tolerance phenotype, characterized by sustained root growth and exclusion of aluminum from the root apex in transgenic plants, as confirmed by hematoxylin assay. In addition, transgenic plants showed higher root citrate exudation into the rhizosphere, suggesting that Al tolerance improvement in these plants could be related to the chelation of the metal by the organic acid anion. These results suggest that BdMATE gene can be used to transform C4 crops of economic importance with improved aluminum tolerance.

  13. The delusion of the Master: the last days of Henry James.

    Science.gov (United States)

    Bartolomeo, Paolo

    2013-11-01

    The novelist Henry James shared with his brother William, the author of the Principles of Psychology, a deep interest in the ways in which personal identity is built through one's history and experiences. At the end of his life, Henry James suffered a vascular stroke in the right hemisphere and developed a striking identity delusion. He dictated in a perfectly clear and coherent manner two letters as if they were written by Napoleon Bonaparte. He also showed signs of reduplicative paramnesia. Negative symptoms resulting from right hemisphere damage may disrupt the feelings of "warmth and intimacy and immediacy" and the "resemblance among the parts of a continuum of feelings (especially bodily feelings)", which are the foundation of personal identity according to William James. On the other hand, a left hemisphere receiving inadequate input from the damaged right hemisphere may produce positive symptoms such as delusional, confabulatory narratives. Other fragments dictated during Henry James's final disease reveal some form of insight, if partial and disintegrated, into his condition. Thus, even when consciousness is impaired by brain damage, something of its deep nature may persist, as attested by the literary characteristics of the last fragments of the Master.

  14. Should bulk cloudwater or fogwater samples obey Henry's law

    Energy Technology Data Exchange (ETDEWEB)

    Pandis, S.N.; Seinfeld, J.H. (Department of Chemical Engineering and Environmental Quality Laboratory, California Institute of Technology, Pasadena, CA (USA))

    1991-06-20

    In this work we prove that mixing of droplets with different {ital p}H that are individually in Henry's law equilibrium with the surrounding atmosphere always results in a bulk mixture that is supersaturated with weak acids like S(IV) and HCOOH and bases like NH{sub 3} with respect to the original atmosphere. The degree of supersaturation of the bulk liquid water sample for a particular species depends on its dissociation constant, on the initial {ital p}H of the bulk droplet mixture, and on the distribution of the {ital p}H and of the liquid water over the droplet spectrum. High supersaturations result only when the {ital p}H of the bulk droplet mixture exceeds the {ital p}K{sub {ital a}} of the species, in which {ital p}H range large {ital p}H differences among droplets of different sizes lead to large deviations from Henry's law for the bulk mixture. The deviation is shown to depend on the ratio of the arithmetic mean to the harmonic mean of the hydrogen ion concentrations of the droplets with the liquid water content used was weighting factor in the calculation of the means. The theory developed can explain observed discrepancies from Henry's law in atmospheric samples and also other observed phenomena like the reported increase of {ital p}H values of bulk aqueous samples during storage. {copyright} American Geophysical Union 1991

  15. The last ride of Henry II of France: orbital injury and a king's demise.

    Science.gov (United States)

    Eftekhari, Kian; Choe, Christina H; Vagefi, M Reza; Eckstein, Lauren A

    2015-01-01

    Jousting was a popular pastime for royalty in the Renaissance era. Injuries were common, and the eye was particularly at risk from the splinters of the wooden lance. On June 30, 1559, Henry II of France participated in a jousting tournament to celebrate two royal weddings. In the third match, Gabriel de Montgomery struck Henry on the right shoulder and the lance splintered, sending wooden shards into his face and right orbit. Despite being cared for by the prominent physicians Ambroise Paré and Andreas Vesalius, the king died 10 days later and was found to have a cerebral abscess. The wound was not explored immediately after the injury; nevertheless, wooden foreign bodies were discovered in the orbit at the time of autopsy. The dura had not been violated, suggesting that an infection may have traveled from the orbit into the brain. Nostradamus and Luca Guarico, the astrologer to the Medici family, had prophesied the death of Henry II of France, but he ignored their warnings and thus changed the course of history in Renaissance Europe. Copyright © 2015 Elsevier Inc. All rights reserved.

  16. Oxalate Content of the Herb Good-King-Henry, Blitum Bonus-Henricus

    Directory of Open Access Journals (Sweden)

    Wanying Li

    2015-05-01

    Full Text Available The total, soluble and insoluble oxalate contents of the leaves, stems and buds of Good-King-Henry (Blitum Bonus-Henricus were extracted and measured using HPLC chromatography. The large, mature leaves contained 42% more total oxalate than in the small leaves and the soluble oxalate content of the large leaves was 33% higher than the smaller leaves. Cooking the mixed leaves, stems and buds in boiling water for two minutes significantly (p < 0.05 reduced the total oxalate when compared to the raw plant parts. Pesto sauce made from mixed leaves contained 257 mg total oxalate/100 g fresh weight; this was largely made up of insoluble oxalates (85% of the total oxalate content. Soup made from mixed leaves contained lower levels of total oxalates (44.26 ± 0.49 mg total oxalate/100 g fresh weight and insoluble oxalate made up 49% of the oxalate contents. The levels of oxalates in the Good-King-Henry leaves were high, suggesting that the leaves should be consumed occasionally as a delicacy because of their unique taste rather than as a significant part of the diet. However, the products made from Good-King-Henry leaves indicated that larger amounts could be consumed as the oxalate levels were reduced by dilution and processing.

  17. BD-22deg3467, a DAO-type Star Exciting the Nebula Abell 35

    Science.gov (United States)

    Ziegler, M.; Rauch, T.; Werner, K.; Koppen, J.; Kruk, J. W.

    2013-01-01

    Spectral analyses of hot, compact stars with non-local thermodynamical equilibrium (NLTE) model-atmosphere techniques allow the precise determination of photospheric parameters such as the effective temperature (T(sub eff)), the surface gravity (log g), and the chemical composition. The derived photospheric metal abundances are crucial constraints for stellar evolutionary theory. Aims. Previous spectral analyses of the exciting star of the nebula A35, BD-22deg3467, were based on He+C+N+O+Si+Fe models only. For our analysis, we use state-of-the-art fully metal-line blanketed NLTE model atmospheres that consider opacities of 23 elements from hydrogen to nickel. We aim to identify all observed lines in the ultraviolet (UV) spectrum of BD-22deg3467 and to determine the abundances of the respective species precisely. Methods. For the analysis of high-resolution and high signal-to-noise ratio (S/N) far-ultraviolet (FUSE) and UV (HST/STIS) observations, we combined stellar-atmosphere models and interstellar line-absorption models to fully reproduce the entire observed UV spectrum. Results. The best agreement with the UV observation of BD-22deg3467 is achieved at T(sub eff) = 80 +/- 10 kK and log g = 7.2 +/- 0.3. While T(sub eff) of previous analyses is verified, log g is significantly lower. We re-analyzed lines of silicon and iron (1/100 and about solar abundances, respectively) and for the first time in this star identified argon, chromium, manganese, cobalt, and nickel and determined abundances of 12, 70, 35, 150, and 5 times solar, respectively. Our results partially agree with predictions of diffusion models for DA-type white dwarfs. A combination of photospheric and interstellar line-absorption models reproduces more than 90% of the observed absorption features. The stellar mass is M approx. 0.48 Solar Mass. Conclusions. BD.22.3467 may not have been massive enough to ascend the asymptotic giant branch and may have evolved directly from the extended horizontal branch

  18. Jofre de Foixa, “Subrafusa ab cabirol” (BdT 304.4

    Directory of Open Access Journals (Sweden)

    Wendy Pfeffer

    2011-11-01

    Full Text Available Jofre de Foixa’s verses “Subrafusa ab cabirol” (BdT 304.4 merit attention for the light the two ‘coblas’ shed on Jofre’s familiarity with his Occitan predecessors, for the information the text provides regarding food practices in his time, and for the use of a food term rare in the Iberian peninsula, “unyo”. The resources of culinary history, specifically fourteenth- and fifteenth-century Languedocian and Catalan cookbooks, allow us better to understand the meaning of Jofre’s lyric.

  19. Ultraviolet observations of planetary nebulae NGC 6572, NGC 5315 and BD + 30/sup 0/ 3639

    Energy Technology Data Exchange (ETDEWEB)

    Torres-Peimbert, S; Pena, M [Universidad Nacional Autonoma de Mexico, Mexico City. Inst. de Astronomia

    1981-01-01

    We present IUE observations of three planetary nebulae. We have obtained the chemical composition of NGC 6572 to be log C = -3.60, log N = -3.67, log O = -3.27, and log Ne = -3.8. For NGC 5315 and BD + 30/sup 0/ 3639, the stellar WR contribution in the UV is very significant, and for these nebulae we are only able to derive the carbon abundance. We found log C = -3.01 and >-3.27, respectively.

  20. VizieR Online Data Catalog: BD+46 442 optical spectra (Bollen+, 2017)

    Science.gov (United States)

    Bollen, D.; van Winckel, H.; Kamath, D.

    2017-08-01

    Reduced high-resolution (R~85000) optical spectra of BD+46 442. These 104 spectra were obtained between July 2009 and January 2016 from the HERMES spectrograph, mounted on the 1.2m Flemish Mercator telescope at La Palma, Canary Islands, Spain. The spectra cover a wavelength range from 3770 to 9000 angstrom in logscale. The flux is given in arbitrary units. The spectra are collected as FITS files. The numbering of the spectra corresponds to the numbering in Table B.1 in the article (e.g. spec_15.fits corresponds to N=15). (2 data files).

  1. Perspectives of Super-Heavy Nuclei research with the upcoming separator-spectrometer setup S3 at GANIL/SPIRAL2 - The VAMOS Gas-Filled separator and AGATA

    Science.gov (United States)

    Theisen, Christophe

    2017-11-01

    Several facilities or apparatus for the synthesis and spectroscopy of the Super-Heavy Nuclei (SHN) are presently under construction in the world, which reflect the large interest for this region of extreme mass and charge, but also for the need of even more advanced research infrastructures. Among this new generation, the GANIL/SPIRAL2 facility in Caen, France, will soon deliver very high intense ion beams of several tens of particle μA. The Super Separator Spectrometer S3 has been designed to exploit these new beams for the study of SHN after separation. It will provide the needed beam rejection, mass selection and full arsenal of state-of-the art detection setups. Still at GANIL, the AGATA new generation gamma-ray tracking array is being operated. The VAMOS high acceptance spectrometer is being upgraded as a gas-filled separator. Its coupling with AGATA will lower the spectroscopic limits for the prompt gamma-ray studies of heavy and super-heavy nuclei. In this proceeding, these new devices will be presented along with a selected physics case.

  2. Effect of hBD2 genetically modified dermal multipotent stem cells on repair of infected irradiated wounds

    International Nuclear Information System (INIS)

    Zong Zhaowen; Li Nan; Xiao Taoyuan

    2010-01-01

    Deficiencies in repair cells and infection are two of the main factors that can hinder the process of wound healing. In the present study, we investigated the ability of human beta-defensin-2 (hBD2) genetically modified dermal multipotent stem cells (dMSCs) to accelerate the healing irradiated wounds complicated by infections. An hBD2 adenovirus expression vector (Adv-hBD2) was firstly constructed and used to infect dMSCs. The antibacterial activity of the supernatant was determined by Kirby-Bauer method and macrodilution broth assay. Time to complete wound healing, residual percentage of wound area, and the number of bacteria under the scar were measured to assess the effects of Adv-hBD2-infected dMSC transplantation on the healing of irradiated wounds complicated by Pseudomonas aeruginosa infection. Results showed that the supernatant from Adv-hBD2-infected dMSCs had obvious antibacterial effects. Transplantation of Adv-hBD2-infected dMSCs killed bacteria in the wound. The complete wound healing time was 19.8±0.45 days, which was significantly shorter than in the control groups (P<0.05). From 14 days after transplantation, the residual wound area was smaller in the experimental group than in the control groups (P<0.05). In conculsion, we found that transplantation of hBD2 genetically modified dMSCs accelerated the healing of wounds complicated by P. aeruginosa infection in whole body irradiated rats. (author)

  3. Effectiveness of an implementation optimisation intervention aimed at increasing parent engagement in HENRY, a childhood obesity prevention programme - the Optimising Family Engagement in HENRY (OFTEN) trial: study protocol for a randomised controlled trial.

    Science.gov (United States)

    Bryant, Maria; Burton, Wendy; Cundill, Bonnie; Farrin, Amanda J; Nixon, Jane; Stevens, June; Roberts, Kim; Foy, Robbie; Rutter, Harry; Hartley, Suzanne; Tubeuf, Sandy; Collinson, Michelle; Brown, Julia

    2017-01-24

    Family-based interventions to prevent childhood obesity depend upon parents' taking action to improve diet and other lifestyle behaviours in their families. Programmes that attract and retain high numbers of parents provide an enhanced opportunity to improve public health and are also likely to be more cost-effective than those that do not. We have developed a theory-informed optimisation intervention to promote parent engagement within an existing childhood obesity prevention group programme, HENRY (Health Exercise Nutrition for the Really Young). Here, we describe a proposal to evaluate the effectiveness of this optimisation intervention in regard to the engagement of parents and cost-effectiveness. The Optimising Family Engagement in HENRY (OFTEN) trial is a cluster randomised controlled trial being conducted across 24 local authorities (approximately 144 children's centres) which currently deliver HENRY programmes. The primary outcome will be parental enrolment and attendance at the HENRY programme, assessed using routinely collected process data. Cost-effectiveness will be presented in terms of primary outcomes using acceptability curves and through eliciting the willingness to pay for the optimisation from HENRY commissioners. Secondary outcomes include the longitudinal impact of the optimisation, parent-reported infant intake of fruits and vegetables (as a proxy to compliance) and other parent-reported family habits and lifestyle. This innovative trial will provide evidence on the implementation of a theory-informed optimisation intervention to promote parent engagement in HENRY, a community-based childhood obesity prevention programme. The findings will be generalisable to other interventions delivered to parents in other community-based environments. This research meets the expressed needs of commissioners, children's centres and parents to optimise the potential impact that HENRY has on obesity prevention. A subsequent cluster randomised controlled pilot

  4. Henri Fayol’un Yönetim Düşüncesi Üzerine Notlar(Notes on Managerial Thought of Henry Fayol

    Directory of Open Access Journals (Sweden)

    Ramazan ŞENGÜL

    2007-01-01

    Full Text Available Henri Fayol, developed a managerial approach which is a perfect guide for both private and public sectors through focusing systematically upon managerial process. A major advantage of Fayol in creating a general managerial doctrine was his pratician side. His managerial thought which was developed in the early 20th century lasted up to our times. The distinguished characteristic of Fayol’s thought was studying the administrative reality through separating it into its functions, in that it helps to understand evolution and operation of organisations. The importance of his doctrine for today is that adapting contemporary managerial techniques into organisations of various kinds needs to refer Fayol’s managerial aproach in one way or another.

  5. Characterization of the cydAB-Encoded Cytochrome bd Oxidase from Mycobacterium smegmatis

    Science.gov (United States)

    Kana, Bavesh D.; Weinstein, Edward A.; Avarbock, David; Dawes, Stephanie S.; Rubin, Harvey; Mizrahi, Valerie

    2001-01-01

    The cydAB genes from Mycobacterium smegmatis have been cloned and characterized. The cydA and cydB genes encode the two subunits of a cytochrome bd oxidase belonging to the widely distributed family of quinol oxidases found in prokaryotes. The cydD and cydC genes located immediately downstream of cydB encode a putative ATP-binding cassette-type transporter. At room temperature, reduced minus oxidized difference spectra of membranes purified from wild-type M. smegmatis displayed spectral features that are characteristic of the γ-proteobacterial type cytochrome bd oxidase. Inactivation of cydA or cydB by insertion of a kanamycin resistance marker resulted in loss of d-heme absorbance at 631 nm. The d-heme could be restored by transformation of the M. smegmatis cyd mutants with a replicating plasmid carrying the highly homologous cydABDC gene cluster from Mycobacterium tuberculosis. Inactivation of cydA had no effect on the ability of M. smegmatis to exit from stationary phase at 37 or 42°C. The growth rate of the cydA mutant was tested under oxystatic conditions. Although no discernible growth defect was observed under moderately aerobic conditions (9.2 to 37.5 × 102 Pa of pO2 or 5 to 21% air saturation), the mutant displayed a significant growth disadvantage when cocultured with the wild type under extreme microaerophilia (0.8 to 1.7 × 102 Pa of pO2 or 0.5 to 1% air saturation). These observations were in accordance with the two- to threefold increase in cydAB gene expression observed upon reduction of the pO2 of the growth medium from 21 to 0.5% air saturation and with the concomitant increase in d-heme absorbance in spectra of membranes isolated from wild-type M. smegmatis cultured at 1% air saturation. Finally, the cydA mutant displayed a competitive growth disadvantage in the presence of the terminal oxidase inhibitor, cyanide, when cocultured with wild type at 21% air saturation in an oxystat. In conjunction with these findings, our results suggest that

  6. Staging Henry Fielding: The Author-Narrator in Tom Jones On Screen

    Directory of Open Access Journals (Sweden)

    Eli Løfaldli

    2017-06-01

    Full Text Available As recent adaptation theory has shown, classic-novel adaptation typically sets issues connected to authorship and literal and figurative ownership into play. This key feature of such adaptations is also central to the screen versions of Henry Fielding’s Tom Jones (1749. In much of Fielding’s fiction, the narrator, typically understood as an embodiment of Fielding himself, is a particularly prominent presence. The author-narrator in Tom Jones is no exception: not only is his presence strongly felt throughout the novel, but through a variety of means, ‘The History of Tom Jones, A Foundling’ is also distinctly marked as being under his control and ownership. The two adaptations of Fielding’s novel, a 1963 film and a 1997 television series, both retain the figure of the author-narrator, but differ greatly in their handling of this device and its consequent thematic ramifications. Although the 1963 film de-emphasises Henry Fielding’s status as proprietor of the story, the author-narrator as represented in the film’s voiceover commentary is a figure of authority and authorial control. In contrast, the 1997 adaptation emphasises Fielding’s ownership of the narrative and even includes the author-narrator as a character in the series, but this ownership is undermined by the irreverent treatment to which he is consistently subjected. The representations of Henry Fielding in the form of the author-narrator in both adaptations are not only indicative of shifting conceptions of authorship, but also of the important interplay between authorship, ownership and adaptation more generally.

  7. Development of low-energy X-ray spectrometry at the Laboratoire National Henri Becquerel

    International Nuclear Information System (INIS)

    Lepy, M.C.; Plagnard, J.

    2007-01-01

    In the frame of the French Metrology Institute, the Laboratoire National Henri Becquerel performs accurate characterization of semiconductor detectors that are in use in a number of applications. Their efficiency calibration, energy resolution and the detailed shape of their response function are parameters of interest for accurate processing of low-energy X-ray spectra to be applied to elements identification and fundamental research studies. The tools specifically developed for low-energy detectors calibration and characterization are described, from the use of radioactivity standard to the development of a tunable monochromatic X-ray source. (Author)

  8. Literary Practice according to Michel Henry: A Philosophical Introduction to his Novels

    Directory of Open Access Journals (Sweden)

    Jean-Baptiste Dussert

    2012-12-01

    Full Text Available Although the author of four novels, Michel Henry never produced an aesthetics of literature. The purpose of this article is, after a presentation of his philosophy of immanence and his concept of life, to locate where the literary practice takes place in his system. In this study, we are not interested in the poetic quality of his works, but in the possibility to base his singular creativity on his philosophical reflection. This leads us to insert literature in the vast phenomenon of culture and ethics, and to grasp the function of poetics in the struggle against barbarism.

  9. Ernest Henry Starling (1866-1927): the scientist and the man

    DEFF Research Database (Denmark)

    Henriksen, Jens H

    2005-01-01

    The pre-eminent achievements of the English physician and physiologist Ernest Henry Starling were his quantitative explanation of the transcapillary transport of fluid, the discovery of the first hormone, secretin, and his formulation of the law of the heart. In some ways Starling was an outsider...... and he was the centre of several scientific and social controversies. However, throughout his life he stressed fundamental scientific attitudes and ideas with remarkable persistence and power, although also balance, and his scientific achievements have stood the test of time....

  10. Elementos de política de gestión en Henry Mintzberg

    OpenAIRE

    García-Álvarez, S. (Santiago); García-Martínez, A.N. (Alejandro Néstor); Múgica, F. (Fernando)

    2016-01-01

    El trabajo de investigación consistió en estudiar un buen número de los escritos de Henry Mintzberg y prácticamente todas sus obras relacionadas con los elementos de política de gestión: no únicamente los libros, sino numerosos artículos y textos relacionados. He leído también muchos libros y artículos de otros autores de management, como Drucker, Collins, Kotter, Pfeffer, Peters y varios más, para enriquecer el texto y contrastar posturas. He estudiado con particular interés y detenimiento l...

  11. Henri Walon: por uma teoria dialética na educação

    Directory of Open Access Journals (Sweden)

    Maria Inês Naujorks

    2000-04-01

    Full Text Available O texto aborda as principais idéias desenvolvidas por Henri Wallon. Tendo como método o materialismo dialético, seu projeto foi o de formular uma "ciência do homem". Para o autor o desenvolvimento é a síntese dialética do biológico e do social e só pode ser entendido à luz das contradições de um processo que se estende por toda vida toda.

  12. Confronting empty spaces: between interpretation and experience in "The Turn of the Screw" by Henry James

    Directory of Open Access Journals (Sweden)

    Antonia Spinelli

    2015-01-01

    Full Text Available The Turn of the Screw by Henry James has inspired the most various critical debates for over a century. What is hidden in the folds of the story? What kind of impact does it have on the reader? Like a borderless nebula who attracts and reflects light from other stars, this novella is permeated by a vide fascinant, by a chaotic and disturbing matter “such stuff as dreams are made”. This feeling of absence and uncertainty, that characterizes the story, developed trough the contribution of readers and critics and it found a further still precious echo in The Innocents, a film directed by Jack Clayton in 1961.

  13. Near-Earth Asteroids 2006 RH120 AND 2009 BD: Proxies for Maximally Accessible Objects?

    Science.gov (United States)

    Barbee, Brent W.; Chodas, Paul W.

    2015-01-01

    NASA's Near-Earth Object Human Space Flight Accessible Targets Study (NHATS) has identified over 1,400 of the approximately 12,800 currently known near-Earth asteroids (NEAs) as more astrodynamically accessible, round-trip, than Mars. Hundreds of those approximately 1,400 NEAs can be visited round-trip for less change-in-velocity than the lunar surface, and dozens can be visited round-trip for less change-in-velocity than low lunar orbit. How accessible might the millions of undiscovered NEAs be? We probe that question by investigating the hypothesis that NEAs 2006 RH120 and 2009 BD are proxies for the most accessible NEAs we would expect to find, and describing possible future NEA population model studies.

  14. [Therapeutic management of bipolar disorder in France and Europe: a multinational longitudinal study (WAVE-bd)].

    Science.gov (United States)

    Bellivier, F; Delavest, M; Coulomb, S; Figueira, M L; Langosch, J M; Souery, D; Vieta, E

    2014-10-01

    Bipolar disorder is a complex disease which requires multiple healthcare resources and complex medical care programs including pharmacological and non pharmacological treatment. If mood stabilizers remain the corner stone for bipolar disorder treatment, the development of atypical antipsychotics and their use as mood stabilizers has significantly modified therapeutic care. At the present time, psychiatrists have a large variety of psychotropic drugs for bipolar disorder: mood stabilizers, atypical antipsychotics, antidepressants, anxiolytics… However, despite the publication of guidelines on pharmacological treatment, with a high degree of consensus, everyday clinical practices remain heterogeneous. Moreover, there are few longitudinal studies to describe therapeutic management of bipolar disorder, whatever the phase of the disease is. Indeed, most of the studies are carried out on a specific phase of the disease or treatment. And there is no study comparing French and European practices. In this paper, we aim to present the comparison of the management of pharmacological treatments of bipolar disorder between France and Europe, using the data of the observational Wide AmbispectiVE study of the clinical management and burden of bipolar disorder (WAVE-bd study). The WAVE-bd study is a multinational, multicentre and non-interventional cohort study of patients diagnosed with BD type I or type II, according to DSM IV-TR criteria, in any phase of the disorder, who have experienced at least one mood event during the 12 months before enrolment. In total, 2507 patients have been included across 8 countries of Europe (480 in France). Data collection was retrospective (from 3 to 12 months), but also prospective (from 9 to 15 months) for a total study length of 12 to 27 months. Main outcome measures were the healthcare resource use and pharmacological treatments. Our results show differences in the therapeutic management of bipolar disorder between France and other European

  15. Balance of plant modeling in TRAC-BD1/MOD1

    International Nuclear Information System (INIS)

    Weaver, W.L.; Giles, M.M.; Mohr, C.M.

    1983-01-01

    The mission of the TRAC-BD1/MOD1 code is to provide a best-estimate analysis capability for Boiling Water Reactor systems and related experimental facilities for the full range of accidents from large and small break Loss-of-Coolant accidents to operational transients including anticipated transients without scram (ATWS), for which point reactor kinetics is adequate (as a first approximation). Recent model developments allow a complete reactor system including the containment and the balance of plant to be modeled. This paper describes the balance of plant models and presents the results of a simulation of a loss-of-feedwater heater transients which was used to assess the performance of the balance of plant models

  16. Mixing and CP-violation in the Bd and Bs systems at ATLAS

    CERN Document Server

    Wharton, Andrew Mark; The ATLAS collaboration

    2016-01-01

    Search for deviations from the standard model is performed in the systems of the neutral B mesons. The Bs system is studied in the decay into J/psi phi. The mixing phase phi_s and the width difference DeltaGamma_s are determined through the simultaneous study of angular distributions in the final state and of the decay time, performed together with flavour tagging at production. The measurement performed by ATLAS with the full LHC Run-1 sample is discussed and compared to the previous world average. The width difference DeltaGamma_d in the Bd system is obtained from the comparison of the decay time distributions in the flavour specific state J/psi K* and in the CP eigenstate J/psi KS. The result obtained from the full sample of data collected by ATLAS at 7 and 8 TeV is the most accurate single measurement of the width difference currently available.

  17. PLANETS AROUND THE K-GIANTS BD+20 274 AND HD 219415

    International Nuclear Information System (INIS)

    Gettel, S.; Wolszczan, A.; Niedzielski, A.; Nowak, G.; Adamów, M.; Zieliński, P.; Maciejewski, G.

    2012-01-01

    We present the discovery of planet-mass companions to two giant stars by the ongoing Penn State-Toruń Planet Search conducted with the 9.2 m Hobby-Eberly Telescope. The less massive of these stars, K5-giant BD+20 274, has a 4.2 M J minimum mass planet orbiting the star at a 578 day period and a more distant, likely stellar-mass companion. The best currently available model of the planet orbiting the K0-giant HD 219415 points to a ∼> Jupiter-mass companion in a 5.7 year, eccentric orbit around the star, making it the longest period planet yet detected by our survey. This planet has an amplitude of ∼18 m s –1 , comparable to the median radial velocity 'jitter', typical of giant stars.

  18. Environmental liabilities in Billings reservoir and its impacts on hydropower generation Plant Henry Borden; Os passivos ambientais no reservatorio Billings e os seus impactos na geracao hidroenergetica da Usina Henry Borden

    Energy Technology Data Exchange (ETDEWEB)

    Almeida, Daniel Ladeira [Universidade Federal do ABC (UFABC), Santo Andre, SP (Brazil)

    2010-07-01

    The primary assertion is that this article argues that the recovery in production of hydropower in Henry Borden (UHB) is the reduction of environmental liabilities in the Billings reservoir. In this context, the aim of this paper is to provide a first consideration of the possibility of recovery of production Henry Borden hydropower plant of recovering the multiple uses of the reservoir. From this perspective, we interviewed representatives of CETESB (Sanitation Environmental Technology Company) and EMAE (Metropolitan Water and Energy Company SA) for consideration of actions that include environmental policies aimed at increasing the production of electricity in Henry Borden in order to obtain results that may contribute to the multiple uses of the Billings reservoir. Noting that the range of laws aimed at protecting the water sources was limited to disjointed public policy that has reduced the resilience of the Billings reservoir. (author)

  19. Purification and characterization of a novel milk-clotting metalloproteinase from Paenibacillus spp. BD3526.

    Science.gov (United States)

    Hang, Feng; Wang, Qinbo; Hong, Qing; Liu, Peiyi; Wu, Zhengjun; Liu, Zhenmin; Zhang, Hao; Chen, Wei

    2016-04-01

    In this study, a milk-clotting enzyme (MCE) isolated from Paenibacillus spp. BD3526 was purified and characterized. The MCE was purified 8.9-fold with a 10.11% recovery using ammonium sulfate precipitation and anion-exchange chromatography and the specific milk-clotting activity (MCA) reached 6791.73 SU/mg. The enzyme was characterized as a 35kDa metalloproteinase, and the zymogen of which was encoded by a 1671 bp gene named zinc metalloproteinase precursor (zmp) with a predicted molecular weight of 59.6 kDa. The optimal temperature for MCA and proteolytic activity (PA) was 65°C and 60°C, respectively. The enzyme was stable over a pH range of 5.0-9.0 and at temperatures below 50°C. The MCA was completely inactivated when the enzyme was heated at 60°C for 30 min, and the PA was totally inactivated for 20 and 10 min when the enzyme was heated at 55°C and 60°C, respectively. The BD3526 enzyme was preferentially active towards κ-casein (κ-CN) and β-casein (β-CN), as determined by sodium dodecyl sulfate-polyacrylamide gels (SDS-PAGE), whereas the hydrolysis of αs-casein (αs-CN) was slow and comparable to that caused by chymosin and asparatic acid proteinase from Rhizomucor miehei. The cleavage site of the metalloproteinase in κ-CN was located at the Met106-Ala107 bond, as determined by mass spectrometry analysis. Copyright © 2016. Published by Elsevier B.V.

  20. Highly efficient decolorization of Malachite Green by a novel Micrococcus sp. strain BD15.

    Science.gov (United States)

    Du, Lin-Na; Zhao, Ming; Li, Gang; Zhao, Xiao-Ping; Zhao, Yu-Hua

    2011-08-01

    Malachite Green (MG) is used for a variety of applications but is also known to be carcinogenic and mutagenic. In this study, a novel Micrococcus sp. (strain BD15) was observed to efficiently decolorize MG. The purposes of this study were to explore the optimal conditions for decolorization and to evaluate the potential use of this strain for MG decolorization. Optical microscope and UV-visible analyses were carried out to determine whether the decolorization was due to biosorption or biodegradation. A Plackett-Burman design was employed to investigate the effect of various parameters on decolorization, and response surface methodology was then used to explore the optimal decolorization conditions. Kinetics analysis and antimicrobial activity tests were also performed. The results indicated that the decolorization by the strain was mainly due to biodegradation. Concentrations of MG, urea, and yeast extract and inoculum size had significantly positive effects on MG decolorization, while concentrations of CuCl(2) and MgCl(2), and temperature had significantly negative effects. The interaction between different parameters could significantly affect decolorization, and the optimal conditions for decolorization were 1.0 g/L urea, 0.9 g/L yeast extract, 100 mg/L MG, 0.1 g/L inoculums (dry weight), and incubation at 25.2°C. Under the optimal conditions, 96.9% of MG was removed by the strain within 1 h, which represents highly efficient microbial decolorization. Moreover, the kinetic data for decolorization fit a second-order model well, and the strain showed a good MG detoxification capability. Based on the results of this study, we propose Micrococcus sp. strain BD15 as an excellent candidate strain for MG removal from wastewater.

  1. PHOTOIONIZATION MODELS OF THE INNER GASEOUS DISK OF THE HERBIG BE STAR BD+65 1637

    Energy Technology Data Exchange (ETDEWEB)

    Patel, P.; Sigut, T. A. A.; Landstreet, J. D., E-mail: ppatel54@uwo.ca [Department of Physics and Astronomy, The University of Western Ontario, London, Ontario Canada N6A 3K7 (Canada)

    2016-01-20

    We attempt to constrain the physical properties of the inner, gaseous disk of the Herbig Be star BD+65 1637 using non-LTE, circumstellar disk codes and observed spectra (3700–10500 Å) from the ESPaDOnS instrument on the Canada–France–Hawaii Telescope. The photoionizing radiation of the central star is assumed to be the sole source of input energy for the disk. We model optical and near-infrared emission lines that are thought to form in this region using standard techniques that have been successful in modeling the spectra of classical Be stars. By comparing synthetic line profiles of hydrogen, helium, iron, and calcium with the observed line profiles, we try to constrain the geometry, density structure, and kinematics of the gaseous disk. Reasonable matches have been found for all line profiles individually; however, no disk density model based on a single power law for the equatorial density was able to simultaneously fit all of the observed emission lines. Among the emission lines, the metal lines, especially the Ca ii IR triplet, seem to require higher disk densities than the other lines. Excluding the Ca ii lines, a model in which the equatorial disk density falls as 10{sup −10} (R{sub *}/R){sup 3} g cm{sup −3} seen at an inclination of 45° for a 50 R{sub *} disk provides reasonable matches to the overall line shapes and strengths. The Ca ii lines seem to require a shallower drop-off as 10{sup −10} (R{sub *}/R){sup 2} g cm{sup −3} to match their strength. More complex disk density models are likely required to refine the match to the BD+65 1637 spectrum.

  2. Ecrire et souffrir : L’inspiration partagée de Constance Fenimore Woolson et de Henry James Literature and Grief: Constance Fenimore Woolson and Henry James, A Common Inspiration

    Directory of Open Access Journals (Sweden)

    Jeannine Hayat

    2007-01-01

    Full Text Available Miss Grief is a story by Constance Fenimore Woolson, an American novelist who often wrote about the difficulty a woman had in becoming an artist — a writer or a painter — in the nineteenth century. This tale is a very strange text, a kind of anticipation of a meeting to come, in Italy, in 1880, between Woolson and Henry James, and a friendship which lasted until the former’s death in 1894. For thirteen years, both writers would share a common inspiration. Death itself could not break the links between the two authors, who were connected even when settled in different European countries. William James, who was a member of the American Society for Psychical Research, probably helped his brother Henry to communicate — or so it appears — in some way with Woolson, even after her fatal accident, or possible suicide, in Venice. Henry James probably had in mind Miss Grief, a story by his dead friend, before writing some of his books. Indeed, Woolson had been the first to develop the image of “the figure in the carpet,” which was later transformed by Henry James. Woolson was also the first to devise a plot which Henry James would later use as a canvas for his novel The Wings of the Dove. What is an author and what is authorship? It seems impossible to separate what is Woolson’s and what is Henry James’s in four works of fiction that are in fact to be read together : Miss Grief, The Figure in the Carpet, The Beast in the Jungle, The Wings of the Dove.

  3. Expression of beta-defensins pBD-1 and pBD-2 along the small tract of the pig: Lack of upregulation in vivo upon Salmonella typhimurium infection

    NARCIS (Netherlands)

    Veldhuizen, E.J.; Dijk, van A.; Tersteeg, M.H.; Kalkhove, S.I.; Meulen, van der J.; Niewold, T.A.; Haagsman, H.P.

    2007-01-01

    Defensins are antimicrobial peptides that play an important role in the innate immune response in the intestine. Up to date, only one ß-defensin (pBD-1), has been described in pig, which was found to be expressed at low levels in the intestine. We set-up a quantitative PCR method to detect the gene

  4. Kierkegaard se, drei grossen ideen” en die ini- siasie van henry van eeden (sewe dae b y die silbersteins

    Directory of Open Access Journals (Sweden)

    L. S. Venter

    1977-03-01

    Full Text Available Die doel van Henry se verblyf by die Silbersteins word vroeg in Sewe dae verwoord as Jock tydens die eerste aandbyeenkoms sê dat Henry „van sekere gevestigde idees” (p. 16 ontslae moet raak. Ook mrs. Silberstein beskou dit as noodsaaklik dat sy on­ skuld vemietig moet word (p. 22. Op die oggendwandeling van die tweede dag herhaal Jock sy stelling van die vorige aand en voeg daaraan toe dat daar baie dinge is wat Henry ,,sal moet leer en verleer” (p. 28. Vir die modeme mens, wat „van die vrug van kennis geëet” het, is daar „geen illussies meer nie” (p. 32.

  5. Theoretical Insight of Physical Adsorption for a Single Component Adsorbent + Adsorbate System: II. The Henry Region

    KAUST Repository

    Chakraborty, Anutosh

    2009-07-07

    The Henry coefficients of a single component adsorbent + adsorbate system are calculated from experimentally measured adsorption isotherm data, from which the heat of adsorption at zero coverage is evaluated. The first part of the papers relates to the development of thermodynamic property surfaces for a single-component adsorbent + adsorbate system1 (Chakraborty, A.; Saha, B. B.; Ng, K. C.; Koyama, S.; Srinivasan, K. Langmuir 2009, 25, 2204). A thermodynamic framework is presented to capture the relationship between the specific surface area (Ai) and the energy factor, and the surface structural and the surface energy heterogeneity distribution factors are analyzed. Using the outlined approach, the maximum possible amount of adsorbate uptake has been evaluated and compared with experimental data. It is found that the adsorbents with higher specific surface areas tend to possess lower heat of adsorption (ΔH°) at the Henry regime. In this paper, we have established the definitive relation between Ai and ΔH° for (i) carbonaceous materials, metal organic frameworks (MOFs), carbon nanotubes, zeolites + hydrogen, and (ii) activated carbons + methane systems. The proposed theoretical framework of At and AH0 provides valuable guides for researchers in developing advanced porous adsorbents for methane and hydrogen uptake. © 2009 American Chemical Society.

  6. Robustness Property of Robust-BD Wald-Type Test for Varying-Dimensional General Linear Models

    Directory of Open Access Journals (Sweden)

    Xiao Guo

    2018-03-01

    Full Text Available An important issue for robust inference is to examine the stability of the asymptotic level and power of the test statistic in the presence of contaminated data. Most existing results are derived in finite-dimensional settings with some particular choices of loss functions. This paper re-examines this issue by allowing for a diverging number of parameters combined with a broader array of robust error measures, called “robust- BD ”, for the class of “general linear models”. Under regularity conditions, we derive the influence function of the robust- BD parameter estimator and demonstrate that the robust- BD Wald-type test enjoys the robustness of validity and efficiency asymptotically. Specifically, the asymptotic level of the test is stable under a small amount of contamination of the null hypothesis, whereas the asymptotic power is large enough under a contaminated distribution in a neighborhood of the contiguous alternatives, thus lending supports to the utility of the proposed robust- BD Wald-type test.

  7. 13 CFR 124.503 - How does SBA accept a procurement for award through the 8(a) BD program?

    Science.gov (United States)

    2010-01-01

    ... under the 8(a) BD program. (g) Basic Ordering Agreements (BOAs). A Basic Ordering Agreement (BOA) is not a contract under the FAR. See 48 CFR 16.703(a). Each order to be issued under the BOA is an... BOA in addition to offering and accepting the BOA itself. (1) SBA will not accept for award on a sole...

  8. 13 CFR 124.203 - What must a concern submit to apply to the 8(a) BD program?

    Science.gov (United States)

    2010-01-01

    ... to, financial statements, Federal personal and business tax returns, and personal history statements... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false What must a concern submit to apply to the 8(a) BD program? 124.203 Section 124.203 Business Credit and Assistance SMALL BUSINESS...

  9. 75 FR 27406 - Airworthiness Directives; Bombardier, Inc. Model BD-100-1A10 (Challenger 300) Airplanes

    Science.gov (United States)

    2010-05-17

    ...., Monday through Friday, except Federal holidays. Examining the AD Docket You may examine the AD docket on....m. and 5 p.m., Monday through Friday, except Federal holidays. The AD docket contains this AD, the... BD-100-1A10 (Challenger 300) airplanes, having serial numbers (S/Ns) 20001 through 20274 inclusive...

  10. Factors affecting the response of the bubble detector BD-100 and a comparison of its response to CR-39

    International Nuclear Information System (INIS)

    Ipe, N.E.; Busick, D.D.; Pollock, R.W.

    1987-08-01

    The BD-100 is a bubble detector available commercially from Chalk River Nuclear Laboratories, Canada for neutron dosimetry. According to the manufacturer, the BD-100 detects neutrons over an energy range of 100 keV to 14 MeV and the dose equivalent response is independent of energy. The sensitivity of the detector is dependent upon its temperature at the time of irradiation. The sensitized detector self-nucleates upon sharp impact and when heated to temperatures of 48 0 C or greater. The BD-100 is insensitive to low energy gamma rays but responds to 6 MeV photons. The sensitivity (bubbles/μSv) of the BD-100 was found to be energy dependent when exposed to standard neutron sources with average energies ranging from 0.5 to 4.5 MeV. The bubbles formed upon irradiation continued to grow in size with time. The response of electrochemically etched CR-39 to the same neutron sources is also reported for comparison

  11. Teaching the “Grandsons of Balzac” a Lesson: Henry James in the 1890’s

    Directory of Open Access Journals (Sweden)

    Dennis F. TREDY

    2004-06-01

    Full Text Available Lyall H. Powers, in Henry James and the Naturalist Movement, dubs the period spanning from “The Art of Fiction” in 1884 to The Tragic Muse in 1890 Henry James’s “Naturalist Experiment”, and rightfully so (Powers 3. There is much evidence, in James’s own notebooks, that The Bostonians was influenced by Daudet’s L’Évangeliste, The Princess Casamassima by Turgeneff’s Virgin Soil, and The Tragic Muse by the narrative techniques of Maupassant (NB 47, Powers 91, NB 92, and Powers effectively show...

  12. Brachypodium distachyon line Bd3-1 resistance is elicited by the barley stripe mosaic virus triple gene block 1 movement protein

    NARCIS (Netherlands)

    Lee, M.Y.; Yan, L.J.; Gorter, F.A.; Kim, B.Y.T.; Cui, Y.; Hu, Y.; Yuan, C.; Grindheim, J.; Ganesan, U.; Liu, Z.Y.; Han, C.G.; Yu, J.L.; Li, D.W.; Jackson, A.O.

    2012-01-01

    Barley stripe mosaic virus North Dakota 18 (ND18), Beijing (BJ), Xinjiang (Xi), Type (TY) and CV21 strains are unable to infect the Brachypodium distachyon Bd3-1 inbred line, which harbours a resistance gene designated Bsr1, but the Norwich (NW) strain is virulent on Bd3-1. Analysis of ND18 and NW

  13. Oxoferryl-Porphyrin Radical Catalytic Intermediate in Cytochrome bd Oxidases Protects Cells from Formation of Reactive Oxygen Species*

    Science.gov (United States)

    Paulus, Angela; Rossius, Sebastiaan Gijsbertus Hendrik; Dijk, Madelon; de Vries, Simon

    2012-01-01

    The quinol-linked cytochrome bd oxidases are terminal oxidases in respiration. These oxidases harbor a low spin heme b558 that donates electrons to a binuclear heme b595/heme d center. The reaction with O2 and subsequent catalytic steps of the Escherichia coli cytochrome bd-I oxidase were investigated by means of ultra-fast freeze-quench trapping followed by EPR and UV-visible spectroscopy. After the initial binding of O2, the O–O bond is heterolytically cleaved to yield a kinetically competent heme d oxoferryl porphyrin π-cation radical intermediate (compound I) magnetically interacting with heme b595. Compound I accumulates to 0.75–0.85 per enzyme in agreement with its much higher rate of formation (∼20,000 s−1) compared with its rate of decay (∼1,900 s−1). Compound I is next converted to a short lived heme d oxoferryl intermediate (compound II) in a phase kinetically matched to the oxidation of heme b558 before completion of the reaction. The results indicate that cytochrome bd oxidases like the heme-copper oxidases break the O–O bond in a single four-electron transfer without a peroxide intermediate. However, in cytochrome bd oxidases, the fourth electron is donated by the porphyrin moiety rather than by a nearby amino acid. The production of reactive oxygen species by the cytochrome bd oxidase was below the detection level of 1 per 1000 turnovers. We propose that the two classes of terminal oxidases have mechanistically converged to enzymes in which the O–O bond is broken in a single four-electron transfer reaction to safeguard the cell from the formation of reactive oxygen species. PMID:22287551

  14. Mapping Henry: Synchrotron-sourced X-ray fluorescence mapping and ultra-high-definition scanning of an early Tudor portrait of Henry VIII

    Energy Technology Data Exchange (ETDEWEB)

    Dredge, Paula; Ives, Simon [Art Gallery of New South Wales (AGNSW), Sydney, NSW (Australia); Howard, Daryl L.; Spiers, Kathryn M. [Australian Synchrotron, Clayton, VIC (Australia); Yip, Andrew [Art Gallery of New South Wales (AGNSW), Sydney, NSW (Australia); University of New South Wales, Laboratory for Innovation in Galleries, Libraries, Archives and Museums (iGLAM), National Institute for Experimental Arts, Sydney, NSW (Australia); Kenderdine, Sarah [University of New South Wales, Laboratory for Innovation in Galleries, Libraries, Archives and Museums (iGLAM), National Institute for Experimental Arts, Sydney, NSW (Australia)

    2015-11-15

    A portrait of Henry VIII on oak panel c. 1535 has recently undergone technical examination to inform questions regarding authorship and the painting's relationship to a group of similar works in the collections of the National Portrait Gallery, London, and the Society of Antiquaries. Due to previous conservation treatments of the painting, the conventional transmission X-radiograph image was difficult to interpret. As a result, the painting underwent high-definition X-ray fluorescence (XRF) elemental mapping on the X-ray fluorescence microscopy beamline of the Australian Synchrotron. Scans were conducted at 12.6 and 18.5 keV, below and above the lead (Pb) L edges, respectively. Typical scan parameters were 120 μm pixel size at 7 ms dwell time, with the largest scan covering an area 545 x 287 mm{sup 2} collected in 23 h (10.8 MP). XRF mapping of the panel has guided the conservation treatment of the painting and the revelation of previously obscured features. It has also provided insight into the process of making of the painting. The informative and detailed elemental maps, alongside ultra-high-definition scans of the painting undertaken before and after varnish and over-paint removal, have assisted in comparison of the finely painted details with the London paintings. The resolution offered by the combination of imaging techniques identifies pigment distribution at an extremely fine scale, enabling a new understanding of the artist's paint application. (orig.)

  15. Mapping Henry: Synchrotron-sourced X-ray fluorescence mapping and ultra-high-definition scanning of an early Tudor portrait of Henry VIII

    International Nuclear Information System (INIS)

    Dredge, Paula; Ives, Simon; Howard, Daryl L.; Spiers, Kathryn M.; Yip, Andrew; Kenderdine, Sarah

    2015-01-01

    A portrait of Henry VIII on oak panel c. 1535 has recently undergone technical examination to inform questions regarding authorship and the painting's relationship to a group of similar works in the collections of the National Portrait Gallery, London, and the Society of Antiquaries. Due to previous conservation treatments of the painting, the conventional transmission X-radiograph image was difficult to interpret. As a result, the painting underwent high-definition X-ray fluorescence (XRF) elemental mapping on the X-ray fluorescence microscopy beamline of the Australian Synchrotron. Scans were conducted at 12.6 and 18.5 keV, below and above the lead (Pb) L edges, respectively. Typical scan parameters were 120 μm pixel size at 7 ms dwell time, with the largest scan covering an area 545 x 287 mm 2 collected in 23 h (10.8 MP). XRF mapping of the panel has guided the conservation treatment of the painting and the revelation of previously obscured features. It has also provided insight into the process of making of the painting. The informative and detailed elemental maps, alongside ultra-high-definition scans of the painting undertaken before and after varnish and over-paint removal, have assisted in comparison of the finely painted details with the London paintings. The resolution offered by the combination of imaging techniques identifies pigment distribution at an extremely fine scale, enabling a new understanding of the artist's paint application. (orig.)

  16. Evaluating the BD-100R [Bubble Technology Industries] as a neutron spectrometer through pressure variation

    International Nuclear Information System (INIS)

    White, B.; Ebert, D.; Munno, F.

    1990-01-01

    Other investigators have evaluated the dose response of neutron bubble dosimeters for possible use as personnel monitors for the U.S. Navy in low level radiation fields. In addition to dose measurements, these devices have been modified to measure the neutron energy spectra. These methods tend to be cumbersome, inaccurate, or both and do not use the same devices as employed in the dosimetry. The BD-100R dosimeter used in this work consists of a test tube containing an elastic polymer with interspersed droplets of two types of Freon; Freon-12 and Freon-114. Each superheated liquid droplet is a potential nucleation site. The minimum energy needed to form a bubble from the nucleation site is given by, E = 16πγ 3 (T)/3(ΔP) 2 , where ΔP is the difference between the vapor pressure of the droplet and the applied pressure. Upon reaching a critical radius, a bubble becomes unstable and grows in size. It may be seen from this equation that the energy deposition required for bubble formation is inversely proportional to the square of the pressure difference. The number of bubbles formed continually decreases with increasing applied pressure, until a pressure is reached where no bubbles are formed since the energy transferred can no longer vaporize the Freon. This investigation is intended to demonstrate the determination of an unknown spectrum utilizing the dosimeter response (number of bubbles formed) as a function of the neutron energy (applied pressure). A set of 12 dosimeters was initially exposed outside the East Beam Port (EBP) at the Maryland University Training Reactor (MUTR). The dosimeters were inside a pressure chamber which could accommodate up to 18 dosimeters. The same set of dosimeters were irradiated using a paraffin moderated PuBe source for which the neutron energy spectrum is unknown. There were eight exposures of six dosimeters at varied pressures in the EBP. The average number of bubbles and standard deviation was measured for each pressure. Data

  17. Disrupting the cinnamyl alcohol dehydrogenase 1 gene (BdCAD1) leads to altered lignification and improved saccharification in Brachypodium distachyon.

    Science.gov (United States)

    Bouvier d'Yvoire, Madeleine; Bouchabke-Coussa, Oumaya; Voorend, Wannes; Antelme, Sébastien; Cézard, Laurent; Legée, Frédéric; Lebris, Philippe; Legay, Sylvain; Whitehead, Caragh; McQueen-Mason, Simon J; Gomez, Leonardo D; Jouanin, Lise; Lapierre, Catherine; Sibout, Richard

    2013-02-01

    Brachypodium distachyon (Brachypodium) has been proposed as a model for grasses, but there is limited knowledge regarding its lignins and no data on lignin-related mutants. The cinnamyl alcohol dehydrogenase (CAD) genes involved in lignification are promising targets to improve the cellulose-to-ethanol conversion process. Down-regulation of CAD often induces a reddish coloration of lignified tissues. Based on this observation, we screened a chemically induced population of Brachypodium mutants (Bd21-3 background) for red culm coloration. We identified two mutants (Bd4179 and Bd7591), with mutations in the BdCAD1 gene. The mature stems of these mutants displayed reduced CAD activity and lower lignin content. Their lignins were enriched in 8-O-4- and 4-O-5-coupled sinapaldehyde units, as well as resistant inter-unit bonds and free phenolic groups. By contrast, there was no increase in coniferaldehyde end groups. Moreover, the amount of sinapic acid ester-linked to cell walls was measured for the first time in a lignin-related CAD grass mutant. Functional complementation of the Bd4179 mutant with the wild-type BdCAD1 allele restored the wild-type phenotype and lignification. Saccharification assays revealed that Bd4179 and Bd7591 lines were more susceptible to enzymatic hydrolysis than wild-type plants. Here, we have demonstrated that BdCAD1 is involved in lignification of Brachypodium. We have shown that a single nucleotide change in BdCAD1 reduces the lignin level and increases the degree of branching of lignins through incorporation of sinapaldehyde. These changes make saccharification of cells walls pre-treated with alkaline easier without compromising plant growth. © 2012 The Authors The Plant Journal © 2012 Blackwell Publishing Ltd.

  18. Publicações póstumas de Henri Fayol: revisitando sua teoria administrativa.

    Directory of Open Access Journals (Sweden)

    Edson Miranda de Souza

    2011-02-01

    Full Text Available O engenheiro francês Henri Fayol (1841-1925 é usualmente apresentado aos estudantes de Administração como o Pai da Escola Clássica de Administração, o que demonstra uma representação limitada da amplitude de sua contribuição para a evolução do pensamento administrativo. Além disso, é frequentemente associado ao seu contemporâneo, o teórico norte-americano Frederick Taylor, sendo aos dois atribuída a defesa de um modelo autoritário de administração. Entretanto, recentemente, pesquisadores descobriram, através do exame de documentos raros e inéditos, um desconhecido retrato desse pioneiro. Este trabalho resulta de uma investigação que buscou levantar fontes de informação bibliográfica disponíveis, publicadas ou não, incluindo resultados de trabalhos de pesquisadores da França, dos Estados Unidos, do Canadá, da Austrália e do Japão. Esses pesquisadores compõem um reduzido grupo de estudiosos, aqui denominados “novos fayolistas” porque retomam, depois de anos de quase amnésia no meio acadêmico, o interesse pelas contribuições de Henri Fayol. Tais estudos revelam conceitos desenvolvidos por Fayol que antecipam aspectos de teorias e práticas da Administração que, somente mais tarde, seriam desenvolvidas, como a Escola de Relações Humanas, a Teoria Contingencial e o Planejamento Estratégico. Ao apresentar as recentes pesquisas sobre o homem e o teórico Henri Fayol, este estudo permite, aos docentes e estudantes de língua portuguesa, acesso a escritos e palestras de sua autoria que, até então, permaneciam desconhecidos.

  19. The study of patient henry Molaison and what it taught us over past 50 years: Contributions to neuroscience

    Directory of Open Access Journals (Sweden)

    Bigya Shah

    2014-01-01

    Full Text Available This section provides a historical perspective and contributions from one of the most studied patients in neuroscience, Henry Molaison (1926-2008, known as H.M during his life to protect his privacy. The peculiar memory deficits seen after an experimental operation for intractable epilepsy led to some critical discoveries pertaining to memory organization in human brain.

  20. All Are Worthy to Know the Earth: Henry De la Beche and the Origin of Geological Literacy

    Science.gov (United States)

    Clary, Renee M.; Wandersee, James H.

    2009-01-01

    Henry T. De la Beche (1796-1855) began his geological career within an elite circle (Geological Society of London, 1817; FRS, 1819), collaborating with influential gentlemen geologists and publishing original research. When his independent income dwindled, De la Beche managed to secure governmental funding for his mapping projects. This led to…

  1. "Undoubtedly a Powerful Influence": Victor Henry's "Antinomies linguistiques" (1896) with an Annotated Translation of the First Chapter.

    Science.gov (United States)

    Joseph, John E.

    1996-01-01

    Discusses Victor Henry's innovative presentation of some underlying contradictions in the premises on which linguistics is founded, cast in the Kantian form of antinomies. The review argues that no science remains more strongly contested than linguistics, a science whose origins are paradoxical and that contains outdated concepts. (30 references)…

  2. Measurement of Henry's Law Constants Using Internal Standards: A Quantitative GC Experiment for the Instrumental Analysis or Environmental Chemistry Laboratory

    Science.gov (United States)

    Ji, Chang; Boisvert, Susanne M.; Arida, Ann-Marie C.; Day, Shannon E.

    2008-01-01

    An internal standard method applicable to undergraduate instrumental analysis or environmental chemistry laboratory has been designed and tested to determine the Henry's law constants for a series of alkyl nitriles. In this method, a mixture of the analytes and an internal standard is prepared and used to make a standard solution (organic solvent)…

  3. The discovery of uranic rays: a short step for Henri Becquerel but a giant step for science

    International Nuclear Information System (INIS)

    Genet, M.

    1995-01-01

    In March 1896, Antoine Henri Becquerel discovered radioactivity. This success is largely due to a tradition of high-level scientific research which prevailed over three generations in the Becquerel family. The circumstances of the discovery and the controversies which followed are reviewed within the framework of their scientific and historical context. (orig.)

  4. Albertet, “En amor trob tantz de mals seignoratges” (BdT 16.13

    Directory of Open Access Journals (Sweden)

    Francesca Sanguineti

    2008-12-01

    Full Text Available The article provides a commentary and a new critical edition of Albertet’s poem “En amor trob tantz de mals seignoratges”, in which the troubadour praises some of the most courtly ladies of his time. The poem can be linked to the genre of the collective eulogy, where the enumerated ladies are praised essentially for political reasons, since the commendation is clearly addressed to the men hidden behind them: famous specimena of this genre are the ‘tournoiements des dames’ by Huon d’Oisy and Richard de Semilli and Raimbaut de Vaqueiras’ “Carros” (BdT 392.32. Albertet’s song starts with a misogynic tone, since the poet declares that celebrating or loving ladies is worthless, given their immoral behaviour, and with a polemic against the strict rules of courtly love. This misogyny, as is further discovered, is a rhetorical device to praise women as well as a tool to renew the genre of the love song from a thematic point of view.

  5. Agrowaste to vanillin conversion by a natural Pediococcus acidilactici strain BD16.

    Science.gov (United States)

    Chakraborty, Debkumar; Kaur, Baljinder; Obulisamy, Karthikeyan; Selvam, Ammaiyappan; Wong, Jonathan W C

    2017-07-01

    Owing to its flavoring, antimicrobial, antioxidant and anticarcinogenic nature, vanillin is widely used in foods, beverages, perfumes and pharmaceutical products. Ferulic acid (FA) is an important precursor of vanillin which is abundant in cereals like maize, rice and wheat and sugar beet. A major drawback of microbial vanillin production from FA is the degradation and biotransformation of toxic vanillin to other phenolic derivatives. The present study is undertaken to explore microbial vanillin production from FA precursor rice bran by employing vanillin-resistant Pediococcus acidilactici BD16, a natural lactic acid bacteria isolate. Extracellular, intracellular and cellular vanillin dehydrogenase activity was found least, which was minimized vanillin degradation, and the strain resists more than 5 g L -1 vanillin in the medium. A metabolomics approach was followed for the detection of FA, vanillin and other metabolites generated during fermentation of rice bran medium. A metabolic pathway was also predicted for vanillin biosynthesis. Approximately 1.06 g L -1 of crude vanillin was recovered from rice-bran-containing medium and this further offers scope for the industrial utilization of the organism and its genetic manipulation to enhance production of biovanillin.

  6. Application of recombinant Pediococcus acidilactici BD16 (fcs +/ech +) for bioconversion of agrowaste to vanillin.

    Science.gov (United States)

    Chakraborty, Debkumar; Selvam, Ammaiyappan; Kaur, Baljinder; Wong, Jonathan Woon Chung; Karthikeyan, Obulisamy Parthiba

    2017-07-01

    Biotechnological production of vanillin is gaining momentum as the natural synthesis of vanillin that is very expensive. Ferulic acid (FA), a costly compound, is used as the substrate to produce vanillin biotechnologically and the making process is still expensive. Therefore, this study investigated the practical use of an agrobiomass waste, rice bran, and provides the first evidence of a cost-effective production of vanillin within 24 h of incubation using recombinant Pediococcus acidilactici BD16 (fcs + /ech + ). Introduction of two genes encoding feruloyl CoA synthetase and enoyl CoA hydratase into the native strain increased vanillin yield to 4.01 g L -1 . Bioconversion was monitored through the transformation of phenolic compounds. A hypothetical metabolic pathway of rice bran during the vanillin bioconversion was proposed with the inserted pathway from ferulic acid to vanillin and compared with that of other metabolic engineered strains. These results could be a gateway of using recombinant lactic acid bacteria for industrial production of vanillin from agricultural waste.

  7. BD+15 2940 AND HD 233604: TWO GIANTS WITH PLANETS CLOSE TO THE ENGULFMENT ZONE

    International Nuclear Information System (INIS)

    Nowak, G.; Niedzielski, A.; Adamów, M.; Maciejewski, G.; Wolszczan, A.

    2013-01-01

    We report the discovery of planetary-mass companions to two red giants by the ongoing Penn State-Toruń Planet Search (PTPS) conducted with the 9.2 m Hobby-Eberly Telescope. The 1.1 M ☉ K0-giant, BD+15 2940, has a 1.1 M J minimum mass companion orbiting the star at a 137.5 day period in a 0.54 AU orbit what makes it the closest—in planet around a giant and possible subject of engulfment as the consequence of stellar evolution. HD 233604, a 1.5 M ☉ K5-giant, is orbited by a 6.6 M J minimum mass planet which has a period of 192 days and a semi-major axis of only 0.75 AU making it one of the least distant planets to a giant star. The chemical composition analysis of HD 233604 reveals a relatively high 7 Li abundance which may be a sign of its early evolutionary stage or recent engulfment of another planet in the system. We also present independent detections of planetary-mass companions to HD 209458 and HD 88133, and stellar activity-induced radial velocity variations in HD 166435, as part of the discussion of the observing and data analysis methods used in the PTPS project.

  8. A Note on Child Neglect in American Victorianism: Henry James’ "The Pupil"

    Directory of Open Access Journals (Sweden)

    F. Gül KOÇSOY

    2016-12-01

    Full Text Available In this study, the theme of “neglected child” in Henry James’ “The Pupil” (1891 is explored. Morgan is a neglected child with unscrupulous parents who hold strictly on the Victorian values which reflect American cultural consciousness in the last decades of 19th century. Although he is a brilliant boy, the family does not love him; because he reminds them of their vulgarity. They neglect him physically and emotionally, seeing him as a burden. Although his tutor tries to keep the boy from the family’s corruption, he contributes to his death; he neglects his illness and deserts him when he is most needy. As an interpreter, James draws attention to the situation of children that are not working but being tutored at home. He criticizes this culture’s general attitude towards children. It is a disturbing social reality and he shows how that materialistic culture victimizes children in terms of neglectful parenting

  9. Design of a gap tunable flux qubit with FastHenry

    Science.gov (United States)

    Akhtar, Naheed; Zheng, Yarui; Nazir, Mudassar; Wu, Yulin; Deng, Hui; Zheng, Dongning; Zhu, Xiaobo

    2016-12-01

    In the preparations of superconducting qubits, circuit design is a vital process because the parameters and layout of the circuit not only determine the way we address the qubits, but also strongly affect the qubit coherence properties. One of the most important circuit parameters, which needs to be carefully designed, is the mutual inductance among different parts of a superconducting circuit. In this paper we demonstrate how to design a gap-tunable flux qubit by layout design and inductance extraction using a fast field solver FastHenry. The energy spectrum of the gap-tunable flux qubit shows that the measured parameters are close to the design values. Project supported by the National Natural Science Foundation of China (Grant Nos. 11374344, 11404386, and 91321208), the National Basic Research Program of China (Grant No. 2014CB921401), and the Strategic Priority Research Program of the Chinese Academy of Sciences (Grant No. XDB07010300).

  10. Henri Mitterand – Critique génétique et sociocritique

    OpenAIRE

    Mitterand, Henri; Biasi, Pierre-Marc de; Herschberg Pierrot, Anne

    2013-01-01

    Henri Mitterand est l’un des fondateurs de la sociocritique en France, et de la génétique zolienne. Il est aussi linguiste, sémioticien et stylisticien. Nous l’avons interrogé sur les relations complexes de la génétique et de la sociocritique. Sociocritique et sociogenèse Pierre-Marc de Biasi – Après une trentaine d’années de recul et d’expérience, quelle place donneriez-vous à la sociocritique et à la sociogenèse dans la construction du nouveau rapport critique qui s’est institué avec les ma...

  11. The Right to the City: From Henri Lefebvre to the Analysis about the Contemporary Capitalist City

    Directory of Open Access Journals (Sweden)

    Frank Molano Camargo

    2016-06-01

    Full Text Available The right to the city, defined by Henri Lefebvre in 1967 as the right of urban inhabitants to build, decide and create the city, and make of it a privileged space of anti-capitalist struggle, is again at the center of political debate. Social scientists, social movements, international aid agencies and States take it as a benchmark for policy analysis and to discuss the urban changes in contemporary capitalist cities. This article discusses the assumptions made by Lefebvre in 1967 and the transformation that the concept of right to the city has had from authors such as David Harvey, Edward Soja and Ana Fani Alessandri Carlos.

  12. About Time. Physics, Philosophy and the Battle Between Albert Einstein and Henri Bergson

    Science.gov (United States)

    Frank, Adam

    The historical relationship between physics and philosophy has had many famous high and low points. The two function best when both can challenge and support each other. In this talk I explore the famous debate between Albert Einstein and Henri Bergson over the nature of time. While history rightly judged Einstein to have won the debate in terms of relativity, there were deeper aspects of Bergsons critique that remain unappreciated. We will explore the different ways philosophy approaches the issue of time. In particular, we will look at the Continental Schools\\x9D, such as Phenomenology, which brings a unique perspective to the debate lying outside the traditional approach of physicists. From this perspective questions related to the act of being an observer, its essential subjective nature and the proper context of physics can be explored.

  13. Review: Henry E. Brady & David Collier (Eds. (2004. Rethinking Social Inquiry: Diverse Tools, Shared Standards

    Directory of Open Access Journals (Sweden)

    Matthias Catón

    2006-03-01

    Full Text Available The book Rethinking Social Inquiry, edited by Henry E. BRADY and David COLLIER, is a response to a book by KING, KEOHANE and VERBA (1994 that aimed to introduce quantitative standards to qualitative research. The authors of the book reviewed here criticize many of the suggestions made there because they argue that qualitative research requires other tools. Nevertheless, they agree that the foundations of research design are similar. The book comprises a comprehensive critique of mainstream quantitative techniques, describes a set of qualitative tools for research, and addresses issues of how to combine qualitative and quantitative approaches to maximize analytical leverage. It is an excellent contribution to the methodological debate in the social sciences. URN: urn:nbn:de:0114-fqs0602309

  14. Henry Moore’s Public Sculpture in the US: The Collaborations with I. M. Pei

    Directory of Open Access Journals (Sweden)

    Alex Potts

    2016-07-01

    Full Text Available The many commissions Henry Moore received for public sculpture in the United States provided the occasion for several quite distinctive works. While not site specific, these were unique, and their final form, scale, and disposition was elaborated with a particular setting in mind. This aspect of Moore’s work in the US, which began with the monumental piece he designed for the Lincoln Center in New York in 1963–65, is examined here by focusing on the productive relationship he forged with the architect I. M. Pei in the 1970s. The sculptures Moore produced in collaboration with Pei respond in suggestive ways to the spatial environments created in American cities by late modern architectural developments. They also realize an oddly effective combination of the biomorphic and abstract that differs both from the bodily conception of Moore’s earlier work and the non-figurative character of much public sculpture of the time.

  15. New Hypersonic Shock Tunnel at the Laboratory of Aerothermodynamics and Hypersonics Prof. Henry T. Nagamatsu

    International Nuclear Information System (INIS)

    Toro, P. G. P.; Minucci, M. A. S.; Chanes, J. B. Jr; Oliveira, A. C.; Gomes, F. A. A.; Myrabo, L. N.; Nagamatsu, Henry T.

    2008-01-01

    The new 0.60-m. nozzle exit diameter hypersonic shock tunnel was designed to study advanced air-breathing propulsion system such as supersonic combustion and/or laser technologies. In addition, it may be used for hypersonic flow studies and investigations of the electromagnetic (laser) energy addition for flow control. This new hypersonic shock tunnel was designed and installed at the Laboratory for of Aerothermodynamics and Hypersonics Prof. Henry T. Nagamatsu, IEAv-CTA, Brazil. The design of the tunnel enables relatively long test times, 2-10 milliseconds, suitable for the experiments performed at the laboratory. Free stream Mach numbers ranging from 6 to 25 can be produced and stagnation pressures and temperatures up to 360 atm. and up to 9,000 K, respectively, can be generated. Shadowgraph and schlieren optical techniques will be used for flow visualization

  16. Fordlândia e Belterra: as cidades de Henry Ford na Amazônia

    OpenAIRE

    Duarte Jr., Antonio Marcos; UERJ & Ibmec/RJ

    2015-01-01

    Ao final de 1945, a Ford Motor Company apresenta sérios problemas de gestão. Nesse contexto, Henry Ford II precisa decidir o que fazer com Fordlândia e Belterra, as duas problemáticas cidades construídas por seu avô na Amazônia brasileira.O caso foi elaborado para utilização em disciplinas na área de finanças corporativas, abordando temas relacionados a análise econômica e de riscos presentes em projetos de investimento.  Pode ser interessante também em diferentes disciplinas que tratem de te...

  17. Publicações póstumas de Henri Fayol: revisitando sua teoria administrativa

    OpenAIRE

    Souza, Edson Miranda De; Aguiar, Afrânio Carvalho

    2011-01-01

    O engenheiro francês Henri Fayol (1841-1925) é usualmente apresentado aos estudantes de Administração como o Pai da Escola Clássica de Administração, o que demonstra uma representação limitada da amplitude de sua contribuição para a evolução do pensamento administrativo. Além disso, é frequentemente associado ao seu contemporâneo, o teórico norte-americano Frederick Taylor, sendo aos dois atribuída a defesa de um modelo autoritário de administração. Entretanto, recentemente, pesquisadores des...

  18. The Allison V. Armour / William Henry Holmes 1895 Expedition to Mexico

    Directory of Open Access Journals (Sweden)

    Warren Haskin

    2001-11-01

    Full Text Available The foundation of the Field Museum's reputation as a place where serious science is practiced was laid by Allison V. Armour and William Henry Holmes in 1895, a little more than a year after the Museum was established. Looking back after a career of almost 60 years as an anthropologist, and having twice been honored as the outstanding practitioner in the field, Holmes described the trip to Mexico (the only expedition he led during his brief tenure as the Museum's first Curator of An­thropology as "one of the most gratifying and important events of my life." It was also one of the most important events in the history of anthropology at the Museum.

  19. Samuel Hartlib on the death of Descartes: a rediscovered letter to Henry More

    Science.gov (United States)

    Penman, Leigh T. I.

    2015-01-01

    This paper discloses the content of a previously overlooked epistle by the Anglo-Prussian intelligencer Samuel Hartlib to Henry More concerning the death of René Descartes. After a discussion situating the letter within the sequence of the More–Hartlib correspondence, an analysis of the rhetorical structure of the epistle is offered, followed by a brief assessment of Hartlib's attitude towards Descartes, and the identification of his source concerning the news of the philosopher's death. An account of the transmission of the letter via a nineteenth-century periodical is also provided. The text of Hartlib's letter and an overlooked passage of Hartlib's diary concerning Descartes's death, which draws on the content of the More letter, are presented as appendixes.

  20. Publicações póstumas de Henri Fayol: revisitando sua teoria administrativa.

    OpenAIRE

    Edson Miranda de Souza; Afrânio Carvalho Aguiar

    2011-01-01

    O engenheiro francês Henri Fayol (1841-1925) é usualmente apresentado aos estudantes de Administração como o Pai da Escola Clássica de Administração, o que demonstra uma representação limitada da amplitude de sua contribuição para a evolução do pensamento administrativo. Além disso, é frequentemente associado ao seu contemporâneo, o teórico norte-americano Frederick Taylor, sendo aos dois atribuída a defesa de um modelo autoritário de administração. Entretanto, recentemente, pesquisadores des...

  1. Anarchism and homosexuality in Wilhelmine Germany: Senna Hoy, Erich Mühsam, John Henry Mackay.

    Science.gov (United States)

    Fähnders, W

    1995-01-01

    Homosexuality and its social and legal suppression were heatedly discussed in early twentieth-century Germany, including on the left. Among the anarchists, positions with markedly diverse forms of argument were espoused by such prominent advocates of individualist anarchism as John Henry Mackay and by others coming from the Bakuninist tradition, such as Senna Hoy and Erich Mühsam. Their writings evidence that prior to World War I and into the 1920s, German anarchists--especially when compared with the Social Democrats--intervened consistently on behalf of individual self-determination extending into the sexual sphere, even though an undercurrent of hostility toward homosexuals persisted within the leftist movement as a whole.

  2. Preliminary assessment report for Fort William Henry Harrison, Montana Army National Guard, Helena, Montana

    International Nuclear Information System (INIS)

    DuWaldt, J.; Meyer, T.

    1993-07-01

    This report presents the results of the preliminary assessment (PA) conducted by Argonne National Laboratory at a Montana Army National Guard (MTARNG) property near Helena, Montana. Preliminary assessments of federal facilities are being conducted to compile the information necessary for completing preremedial activities and to provide a basis for establishing corrective actions in response to releases of hazardous substances. The principal objective of the PA is to characterize the site accurately and determine the need for further action by examining site activities, quantities of hazardous substances present, and potential pathways by which contamination could affect public health and the environment. This PA satisfies, for the Fort William Henry Harrison property, requirements of the Department of Defense Installation Restoration Program

  3. HENRY H. CHEEK AND TRANSFORMISM: NEW LIGHT ON CHARLES DARWIN'S EDINBURGH BACKGROUND.

    Science.gov (United States)

    Jenkins, Bill

    2015-06-20

    Evidence for the transformist ideas espoused by Henry H. Cheek (1807-33), a contemporary of Charles Darwin's at the University of Edinburgh, sheds new light on the intellectual environment of Edinburgh in the late 1820s and early 1830s. Cheek was the author of several papers dealing with the transmutation of species influenced by the theories of Etienne Geoffroy Saint-Hilaire (1772-1844), Jean-Baptiste Lamarck (1744-1829) and the Comte de Buffon (1707-88). Some of these were read to student societies, others appeared in the Edinburgh Journal of Natural and Geographical Science, which Cheek edited between 1829 and 1831. His writings give us a valuable window onto some of the transformist theories that were circulating among Darwin's fellow medical students in the late 1820s, to which Darwin would have been exposed during his time in Edinburgh, and for which little other concrete evidence survives.

  4. How the Other Half Lives: Under the Arch with Lady Henry Somerset

    Directory of Open Access Journals (Sweden)

    Paisana Joanne

    2017-10-01

    Full Text Available The reforming work of Isabella Caroline Somerset (Lady Henry Somerset 1851-1921 is largely overlooked today. Dedicated to women’s causes at home and abroad and to temperance in particular, having first-hand knowledge of the privileged and the underprivileged, this determined, multi-talented and opinionated woman uncharacteristically wrote a fictional novel, Under the Arch (1906. In the novel, London aristocrats are portrayed rubbing shoulders with slum dwellers, but there is little real connection. The problems that the social policies introduced by the Liberals from 1906-1914 would address are nevertheless highlighted. It can be no coincidence that Somerset was well acquainted with many of these politicians. The themes of relieving the poor, Christian doctrine, marriage, women’s suffrage and imperialism are addressed, although Somerset’s focus is simply on “doing good” and loving one’s neighbour

  5. Genealogía de la conciencia en la filosofía de Henri Bergson

    OpenAIRE

    Urquijo Reguera, Mariana

    2016-01-01

    Esta investigación se propone mostrar la concepción de la conciencia de Henri Bergson (1859-1941) a través de una lectura crítica de su filosofía. El análisis recorre los textos del autor exponiendo su filosofía de la duración, frente a la filosofía que piensa en el espacio. El objetivo de este estudio ha sido demostrar la vigencia de su filosofía de cara a un diálogo con la ciencia contemporánea, su actualidad para pensar lso problemas filosóficos y los problemas contemporáneos. Partiendo d...

  6. Henry Solomon Wellcome: A philanthropist and a pioneer sponsor of medical research in the Sudan.

    Science.gov (United States)

    Adeel, Ahmed Awad A

    2013-01-01

    Henry Solomon Wellcome, the famous drug manufacturer had a fascinating association with the Sudan. Besides supporting tropical medicine research in this country, he established an extensive project in the Sudan that aimed at combining archeological excavations, philanthropy and social reform. This article is an archives-based account on this side of Wellcome's association with the Sudan. The article starts with Wellcome's early years in the American Midwest and the evolution of his career and his rise as a world-renowned drug manufacturer. After the battle of Omdurman, Wellcome visited Sudan in 1900 - 1901 where he offered to support the establishment of the research laboratories which later came to be known as the Wellcome Tropical Research Laboratories in Khartoum. He then became directly involved in the planning and running of extensive archeological excavations in the central Sudan. This project served as a field in which Wellcome found an outlet for his philanthropy. More than 4000 labourers were employed in Jebel Moya. Professional archeologists and anatomists were recruited by Wellcome to supervise the work, and all the requirements in terms of equipment were catered for. Wellcome devised a Savings Bank System whereby part of the earnings of each labourer were saved to him till the end of the season. He also introduced one of his innovations: aerial photography using box kite which was used for the first time in archeology. Wellcome made it a rule that no applicant should be turned away. The Camp Commandant had to find suitable work for each applicant, including the handicapped who were assigned to appropriate jobs like mending baskets or cutting grass for building huts. Wellcome's welfare work had a significant impact on the local inhabitants of Jebel Moya. Henry Solomon Wellcome, 1906. Oil painting by Hugh Goldwin Riviere. Credit: Wellcome Library.

  7. Style and non-style in anatomical illustration: From Renaissance Humanism to Henry Gray.

    Science.gov (United States)

    Kemp, Martin

    2010-02-01

    Style is a familiar category for the analysis of art. It is less so in the history of anatomical illustration. The great Renaissance and Baroque picture books of anatomy illustrated with stylish woodcuts and engravings, such as those by Charles Estienne, Andreas Vesalius and Govard Bidloo, showed figures in dramatic action in keeping with philosophical and theological ideas about human nature. Parallels can be found in paintings of the period, such as those by Titian, Michelangelo and Hans Baldung Grien. The anatomists also claimed to portray the body in an objective manner, and showed themselves as heroes of the discovery of human knowledge. Rembrandt's painting of Dr Nicholas Tulp is the best-known image of the anatomist as hero. The British empirical tradition in the 18th century saw William Cheselden and William Hunter working with techniques of representation that were intended to guarantee detailed realism. The ambition to portray forms life-size led to massive volumes, such as those by Antonio Mascagni. John Bell, the Scottish anatomist, criticized the size and pretensions of the earlier books and argued for a plain style adapted to the needs of teaching and surgery. Henry Gray's famous Anatomy of 1858, illustrated by Henry Vandyke Carter, aspired to a simple descriptive mode of functional representation that avoided stylishness, resulting in a style of its own. Successive editions of Gray progressively saw the replacement of Gray's method and of all his illustrations. The 150th anniversary edition, edited by Susan Standring, radically re-thinks the role of Gray's book within the teaching of medicine.

  8. Never say Never. About the Restoration of Henry van de Velde’s Booktower

    Directory of Open Access Journals (Sweden)

    Sylvia van Peteghem

    2006-08-01

    Full Text Available The role of the central library within the university of Ghent (27.000 students is fourfold: it is the centre of the library’s network and its reorganisation, trying to get the current number (> 300 of libraries down. It is the digital library in all its aspects, it is the repository library for cultural heritage and “passive” collections and it offers a working place in its wonderful book tower of Henry van de Velde. The story of the book tower starts in the 1930s when Henry van de Velde was asked to build a University Library and offices for the department of Art history. His tower-idea was not exactly what the chief librarian had in mind, so he had to (network hard to get the building he wanted. It was finished on the verge of the second world war. The concrete building has a height of 64 meter, has 24 floors and a “belvedere” and houses almost 3 million books in closed racks. The university did not neglect the tower during all these years, but was not always aware of the historical value and often choose the cheapest way for building matters. A couple of years ago a private person bought the Van de Velde archive of the book tower (which was in private hands, got fascinated with the building, got angry because of lack of care and networked (maybe as hard as Van de Velde once did to get it built to get it restored. The board of directors of the university said yes to the restoration (estimated on 41 million Euro in September 2005.

  9. Detection of Mycobacterium chelonae, Mycobacterium abscessus Group, and Mycobacterium fortuitum Complex by a Multiplex Real-Time PCR Directly from Clinical Samples Using the BD MAX System.

    Science.gov (United States)

    Rocchetti, Talita T; Silbert, Suzane; Gostnell, Alicia; Kubasek, Carly; Campos Pignatari, Antonio C; Widen, Raymond

    2017-03-01

    A new multiplex PCR test was designed to detect Mycobacterium chelonae, Mycobacterium abscessus group, and Mycobacterium fortuitum complex on the BD MAX System. A total of 197 clinical samples previously submitted for mycobacterial culture were tested using the new protocol. Samples were first treated with proteinase K, and then each sample was inoculated into the BD MAX Sample Buffer Tube. Extraction and multiplex PCR were performed by the BD MAX System, using the BD MAX ExK TNA-3 extraction kit and BD TNA Master Mix, along with specific in-house designed primers and probes for each target. The limit of detection of each target, as well as specificity, was evaluated. Of 197 clinical samples included in this study, 133 were positive and 60 were negative for mycobacteria by culture, and another 4 negative samples were spiked with M. chelonae ATCC 35752. The new multiplex PCR on the BD MAX had 97% concordant results with culture for M. abscessus group detection, 99% for M. chelonae, and 100% for M. fortuitum complex. The new multiplex PCR test performed on the BD MAX System proved to be a sensitive and specific test to detect M. chelonae, M. abscessus group, and M. fortuitum complex by real-time PCR on an automated sample-in results-out platform. Copyright © 2017 American Society for Investigative Pathology and the Association for Molecular Pathology. Published by Elsevier Inc. All rights reserved.

  10. Efficacy of rhBMP-2 Loaded PCL/β-TCP/bdECM Scaffold Fabricated by 3D Printing Technology on Bone Regeneration

    Directory of Open Access Journals (Sweden)

    Eun-Bin Bae

    2018-01-01

    Full Text Available This study was undertaken to evaluate the effect of 3D printed polycaprolactone (PCL/β-tricalcium phosphate (β-TCP scaffold containing bone demineralized and decellularized extracellular matrix (bdECM and human recombinant bone morphogenetic protein-2 (rhBMP-2 on bone regeneration. Scaffolds were divided into PCL/β-TCP, PCL/β-TCP/bdECM, and PCL/β-TCP/bdECM/BMP groups. In vitro release kinetics of rhBMP-2 were determined with respect to cell proliferation and osteogenic differentiation. These three reconstructive materials were implanted into 8 mm diameter calvarial bone defect in male Sprague-Dawley rats. Animals were sacrificed four weeks after implantation for micro-CT, histologic, and histomorphometric analyses. The findings obtained were used to calculate new bone volumes (mm3 and new bone areas (%. Excellent cell bioactivity was observed in the PCL/β-TCP/bdECM and PCL/β-TCP/bdECM/BMP groups, and new bone volume and area were significantly higher in the PCL/β-TCP/bdECM/BMP group than in the other groups (p<.05. Within the limitations of this study, bdECM printed PCL/β-TCP scaffolds can reproduce microenvironment for cells and promote adhering and proliferating the cells onto scaffolds. Furthermore, in the rat calvarial defect model, the scaffold which printed rhBMP-2 loaded bdECM stably carries rhBMP-2 and enhances bone regeneration confirming the possibility of bdECM as rhBMP-2 carrier.

  11. Genital and extra-genital screening for gonorrhoea using the BD Probetec ET system with an in-house PCR method targeting the porA pseudogene as confirmatory test

    DEFF Research Database (Denmark)

    Skovgaard, Sissel; Larsen, Helle Kiellberg; Sand, Carsten

    2012-01-01

    for Chlamydia trachomatis testing were also examined for GC on the BD Viper™ platform using the BD Probetec ET system. In order to avoid false-positive results all GC BD reactive samples were re-tested using a PCR method with the porA pseudogene as target. Using this method we screened 170% more samples for GC...

  12. A business case for on-site generation: The BD biosciences pharmingen project

    Energy Technology Data Exchange (ETDEWEB)

    Firestone, Ryan; Creighton, Charles; Bailey, Owen; Marnay, Chris; Stadler, Michael

    2003-09-01

    Deregulation is haltingly changing the United States electricity markets. The resulting uncertainty and/or rising energy costs can be hedged by generating electricity on-site and other benefits, such as use of otherwise wasted heat, can be captured. The Public Utility Regulatory Policy Act (PURPA) of 1978 first invited relatively small-scale generators ({ge} 1 MW) into the electricity market. The advent of efficient and reliable small scale and renewable equipment has spurred an industry that has, in recent years, made even smaller (business scale) electricity generation an economically viable option for some consumers. On-site energy capture and/or conversion, known as distributed energy resources (DER), offers consumers many benefits, such as economic savings and price predictability, improved reliability, control over power quality, and emissions reductions. Despite these benefits, DER adoption can be a daunting move to a customer accustomed to simply paying a monthly utility bill. San Diego is in many ways an attractive location for DER development: It has high electricity prices typical of California and a moderate climate i.e. energy loads are consistent throughout the year. Additionally, the price shock to San Diego Gas and Electric (SDG&E) customers during the summer of 2000 has interested many in alternatives to electricity price vulnerability. This report examines the business case for DER at the San Diego biotechnology supply company, BD Biosciences Pharmingen, which considered DER for a building with 200-300 kW base-load, much of which accommodates the refrigerators required to maintain chemicals. Because of the Mediterranean climate of the San Diego area and the high rate of air changes required due to on-site use of chemicals, modest space heating is required throughout the year. Employees work in the building during normal weekday business hours, and daily peak loads are typically about 500 kW.

  13. BD -22 5866: A Low-Mass, Quadruple-lined Spectroscopic and Eclipsing Binary

    Science.gov (United States)

    Shkolnik, Evgenya; Liu, Michael C.; Reid, I. Neill; Hebb, Leslie; Cameron, Andrew C.; Torres, Carlos A.; Wilson, David M.

    2008-08-01

    We report our discovery of an extremely rare, low-mass, quadruple-lined spectroscopic binary BD -22 5866 (=NLTT 53279, integrated spectral type = M0 V), found during an ongoing search for the youngest M dwarfs in the solar neighborhood. From the cross-correlation function, we are able to measure relative flux levels, estimate the spectral types of the components, and set upper limits on the orbital periods and separations. The resulting system is hierarchical, composed of a K7 + K7 binary and an M1 + M2 binary with semimajor axes of aAsin iA system was unresolved with published adaptive optics imaging, limits the projected physical separation of the two binaries at the time of the observation to dABlesssim 4.1 AU at the photometric distance of 51 pc. The maximum observed radial velocity difference between the A and B binaries limits the orbit to aABsin iAB systems, we speculate that an early dynamical process reduced the size of the system, such as the interaction of the two binaries with a circumquadruple disk. Intensive photometric, spectroscopic, and interferometric monitoring, as well as a parallax measurement of this rare quadruple system, is certainly warranted. Based on observations collected at the W. M. Keck Observatory and the Canada-France-Hawaii Telescope (CFHT). The Keck Observatory is operated as a scientific partnership between the California Institute of Technology, the University of California, and NASA, and was made possible by the generous financial support of the W. M. Keck Foundation. The CFHT is operated by the National Research Council of Canada, the Centre National de la Recherche Scientifique of France, and the University of Hawaii.

  14. Evaluation of the BD BACTEC FX blood volume monitoring system as a continuous quality improvement measure.

    Science.gov (United States)

    Coorevits, L; Van den Abeele, A-M

    2015-07-01

    The yield of blood cultures is proportional to the volume of blood cultured. We evaluated an automatic blood volume monitoring system, recently developed by Becton Dickinson within its BACTEC EpiCenter module, that calculates mean volumes of negative aerobic bottles and generates boxplots and histograms. First, we evaluated the filling degree of 339 aerobic glass blood cultures by calculating the weight-based volume for each bottle. A substantial amount of the bottles (48.3%) were inadequately filled. Evaluation of the accuracy of the monitoring system showed a mean bias of -1.4 mL (-15.4%). Additional evaluation, using the amended software on 287 aerobic blood culture bottles, resulted in an acceptable mean deviation of -0.3 mL (-3.3%). The new software version was also tested on 200 of the recently introduced plastic bottles, which will replace the glass bottles in the near future, showing a mean deviation of +2.8 mL (+26.7%). In conclusion, the mean calculated volumes can be used for the training of a single phlebotomist. However, filling problems appear to be masked when using them for phlebotomist groups or on wards. Here, visual interpretation of boxplots and histograms can serve as a useful tool to observe the spread of the filling degrees and to develop a continuous improvement program. Re-adjustment of the software has proven to be necessary for use with plastic bottles. Due to our findings, BD has developed further adjustments to the software for validated use with plastic bottles, which will be released soon.

  15. High level expression of human epithelial β-defensins (hBD-1, 2 and 3 in papillomavirus induced lesions

    Directory of Open Access Journals (Sweden)

    Chong Kong T

    2006-09-01

    Full Text Available Abstract Background Epithelial defensins including human β-defensins (hBDs and α-defensins (HDs are antimicrobial peptides that play important roles in the mucosal defense system. However, the role of defensins in papillomavirus induced epithelial lesions is unknown. Results Papilloma tissues were prospectively collected from 15 patients with recurrent respiratory papillomatosis (RRP and analyzed for defensins and chemokine IL-8 expression by quantitative, reverse-transcriptase polymerase chain reaction (RT-PCR assays. HBD-1, -2 and -3 mRNAs were detectable in papilloma samples from all RRP patients and the levels were higher than in normal oral mucosal tissues from healthy individuals. Immunohistochemical analysis showed that both hBD-1 and 2 were localized in the upper epithelial layers of papilloma tissues. Expression of hBD-2 and hBD-3 appeared to be correlated as indicated by scatter plot analysis (r = 0.837, p Conclusion Human β-defensins are upregulated in respiratory papillomas. This novel finding suggests that hBDs might contribute to innate and adaptive immune responses targeted against papillomavirus-induced epithelial lesions.

  16. The radiation linked to uranium natural radioactivity enlightened by Abel Niepce long time before Henri Becquerel;Les rayonnements lies a la radioactivite naturelle de l'uranium mis en evidence par Abel Niepce bien avant Henri Becquerel

    Energy Technology Data Exchange (ETDEWEB)

    Fournier, J.; Niepce, J.C.

    2009-09-15

    Abel Niepce was rarely mentioned during the celebration of the centenary of the radioactivity discovery.This discovery, supposed due to chance alone, is entirely attributed to Henri Becquerel. But Abel Niepce who made the first observation of radiation from uranium with the impression of a photographic plate, but without giving it meaning. This is a slow process which in forty years, from an observation misunderstood by Abel Niepce to its interpretation by Frederick Soddy, through the experiments of Henri Becquerel and thanks to developments in other knowledge (electron, X-rays) has led to a scientific progress known under the term of radioactivity, name given by Marie Slodowska-Curie. (N.C.)

  17. Effect of chloride substitution on the order–disorder transition in NaBH{sub 4} and Na{sup 11}BD{sub 4}

    Energy Technology Data Exchange (ETDEWEB)

    Olsen, Jørn Eirik [Institute for Energy Technology, Physics Department, P.O. Box 40, NO-2027 Kjeller (Norway); Karen, Pavel [University of Oslo, Department of Chemistry, P.O. Box 1033 Blindern, NO-0315 Oslo (Norway); Sørby, Magnus H. [Institute for Energy Technology, Physics Department, P.O. Box 40, NO-2027 Kjeller (Norway); Hauback, Bjørn C., E-mail: bjorn.hauback@ife.no [Institute for Energy Technology, Physics Department, P.O. Box 40, NO-2027 Kjeller (Norway)

    2014-02-25

    Graphical abstract: Interactions that order the BD{sub 4}{sup -} tetrahedra below the order–disorder transition became increasingly frustrated by the solute in the Na({sup 11}BD{sub 4}){sub 1−x}Cl{sub x} solid solutions, and the order disappears at x = 0.158. Highlights: • The order–disorder transition temperature for Na(BH{sub 4}){sub 1−x}Cl{sub x} and Na({sup 11}BD{sub 4}){sub 1−x}Cl{sub x} is highly dependent on the Cl-content, x. • The transition is characterized by DSC for Na({sup 11}BD{sub 4}){sub 1−x}Cl{sub x} for x = 0, 0.10 and 0.15. • No transition is observed for x ⩾ 0.20 on cooling to 8 K. • The crystal structures are reported for Na{sup 11}BD{sub 4} at room temperature and 8 K and Na({sup 11}BD{sub 4}){sub 1−x}Cl{sub x} (x = 0.10, 0.15, 0.20 and 0.25) at 8 K from powder neutron diffraction. -- Abstract: Phase transition associated with anion disordering over two orientations in Na{sup 11}BD{sub 4} (NaBH{sub 4}) and its solid solutions with NaCl, Na({sup 11}BD{sub 4}){sub 1−x}Cl{sub x}, is investigated with powder diffraction (neutron and synchrotron radiation), differential scanning calorimetry and Raman spectroscopy. Upon heating, the transition temperature extrapolated to zero rate of heating is 192.2 K for Na{sup 11}BD{sub 4}, ΔS = 4.41 J/mol K, hysteresis 1.7 K and the volume increase 0.43%. Thermal parameters of the transition in Na({sup 11}BD{sub 4}){sub 1−x}Cl{sub x} follow a colligative-property model of an ideal solution, with x = 0.158(1) as the critical concentration at which the ordering interactions and the transition itself are eliminated. On approaching this limit, the tetragonal distortion of the ordered structure decreases somewhat towards the cubic average, and this is associated with a partial disorder of the tetrahedral anions seen by diffraction methods. In fact, a 3% disorder is already present in the pure solvent of the solid solution (Na{sup 11}BD{sub 4}) at 8 K.

  18. Expression of human beta-defensins-1-4 in thyroid cancer cells and new insight on biologic activity of hBD-2 in vitro.

    Science.gov (United States)

    Zhuravel, O V; Gerashchenko, O L; Khetsuriani, M R; Soldatkina, M A; Pogrebnoy, P V

    2014-09-01

    The study was aimed on analysis of human beta-defensin-1-4 (hBDs) mRNA expression in cultured thyroid cancer cells and evaluation of effects of recombinant hBD-2 (rec-hBD-2) on growth patterns, migration properties and expression of E-cadherin and vimentin in these cells. The study was performed on cultured follicular thyroid cancer WRO cells, papillary thyroid cancer TPC1 cells, and anaplastic thyroid cancer KTC-2 cells. For analysis of hBD-1-4 mRNA expression in thyroid cancer cells, semiquantitative RT-PCR was used. Effects of rec-hBD-2 on cell proliferation, viability, and migration were analyzed using direct cell counting, MTT test, and scratch assay respectively. Expression of vimentin and E-cadherin was evaluated by quantitative PCR (qPCR). By the data of RT-PCR, all three studied thyroid cancer cell lines express hBD-1 and -4 mRNA, but not hBD-2 mRNA, while hBD-3 expression was detected in WRO and KTC-2 cells. The treatment of TPC-1, WRO, and KTC-2 cells with 100-1000 nM rec-hBD-2 resulted in significant concentration-dependent suppression of cell proliferation, viability, and migratory property. By the data of qPCR, significant up-regulation of vimentin expression was registered in KTC-2 and WRO cells treated with 500 nM rec-hBD-2. Significant down-regulation of E-cadherin expression (p cells treated with the defensin. Also, it has been shown that TPC-1 cells treated with 500 nM rec-hBD-2 acquired more elongated morphology. The data demonstrate that hBD-2 in concentrations higher than 100 nM exerts significant concentration-dependent suppression of thyroid cancer cell growth and migration, and affects vimentin and E-cadherin expression dependent on histologic type of thyroid cancer cells.

  19. Une autre ville pour une autre vie. Henri Lefebvre et les situationnistes

    Directory of Open Access Journals (Sweden)

    Philippe Simay

    2008-12-01

    Full Text Available L’un des traits distinctifs du mouvement situationniste est de s’être constamment préoccupé de la question urbaine. Conçue comme l’espace de production de la société du spectacle mais aussi comme un terrain de lutte et d’expérimentation, la ville a représenté pour ce mouvement estudiantin, proche d’Henri Lefebvre, le lieu d’une réinvention radicale de la vie quotidienne. Cet article revient sur la critique situationniste de l’urbanisme de l’après-guerre ainsi que sur les pratiques auxquelles elle a donné lieu (détournement, dérive, cartes psychogéographiques, construction de situations éphémères. Celles-ci peuvent être regardées comme la première expression d’un « droit à la ville », tel que l’entendait Lefebvre. Reste à savoir si le groupe de Guy Debord souhaitait véritablement « changer la ville pour changer la vie » ou si la ville n’était que le théâtre d’une révolution à venir.One of the distinctive traits of the situationist movement is its constant preoccupation with the urban issue. For this student movement close to Henri Lefebvre, the city has been thought of as a choice generic location for the production of the Society of the Spectacle, but also as a test ground for struggle and experimentation – the place where a radical reinvention of daily life can occur. This paper goes back to the situationist critique of post-war urbanism, as well as the behaviors and practices it has given birth to (misappropriation, drifts in meaning, psychogeographic maps, the construct of short-lived situations. These can be seen as the first expression of a « right to the city », in the sense Lefebvre originally meant it have. However, it is still unknown whether Guy Debord's group really wished to « change city-life to change life itself », or if to them the city was merely a theater for the enactment of a revolution to come.

  20. HB1204: Deep-Sea Corals and Benthic Habitats in Northeast Deepwater Canyons on NOAA Ship Henry Bigelow between 20120703 and 20120718

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — A multi-disciplinary team of scientists on the Henry Bigelow HB1204 mission surveyed and ground-truthed known or suspected deep-sea coral habitats associated with...

  1. Kuidas kommunikatsiooniga raha kaasata ehk sõna saab härra ühisrahastus / Henri Laupmaa ; intervjueerinud Dea Martinjonis

    Index Scriptorium Estoniae

    Laupmaa, Henri

    2015-01-01

    Intervjuu IT-ettevõtja, kodanikuühiskonna arendaja ning toetusplatvormi Hooandja ühe käivitaja Henri Laupmaaga Hooandja platvormi õnnestunud projektidest, uuest ühisrahastusplatvormist Fundwise, kommunikatsioonist ühisrahastusprojektide ellu viimisel

  2. [Crusading and chronicle writing on the medieval Baltic frontier: A companion to the chronicle of Henry of Livonia] / Radosław Biskup

    Index Scriptorium Estoniae

    Biskup, Radosław

    2014-01-01

    Arvustus: Crusading and chronicle writing on the medieval Baltic frontier : a companion to the chronicle of Henry of Livonia, eds. Marek Tamm, Linda Kaljundi, Carsten Selch Jensen. Farnham ; Burlington (Vt.) : Ashgate, c2011

  3. Polystyrene copolymer supported by substituted (1R,2R)-1,2-diphenylethane-1,2-diamine-copper(II) complexes: a recyclable catalyst for asymmetric Henry reactions

    Czech Academy of Sciences Publication Activity Database

    Androvič, L.; Drabina, P.; Panov, I.; Frumarová, Božena; Kalendová, A.; Sedlák, M.

    2014-01-01

    Roč. 25, č. 9 (2014), s. 775-780 ISSN 0957-4166 Institutional support: RVO:61389013 Keywords : cooper complexes * copolymers * asymmetric Henry reaction Subject RIV: CC - Organic Chemistry Impact factor: 2.155, year: 2014

  4. The National Shipbuilding Research Program. Proceedings of the REAPS Technical Symposium. Paper No. 21: Development of Effective Computer Capabilities by the J. J. Henry Company

    National Research Council Canada - National Science Library

    Fritz, W. B

    1980-01-01

    On April 2, 1980, the J. J. Henry Company, Inc signed an agreement with Cali & Associates to use the SPADES system of computer programs to enhance its preliminary contract and detail design service for its clients...

  5. A unified description of adsorption on real surfaces from the Henry Range to the formation of the liquid layer

    Energy Technology Data Exchange (ETDEWEB)

    Cerofolini, G F

    1977-01-01

    A unified description of adsorption on real surfaces from the Henry Range to the formation of the liquid layer was developed on the basis of the BET theory and the assumption that sites on real surfaces are not energetically homogeneous. The model describes the successive Henry, Dubinin-Radushkevich, Freundlich, and multilayer BET behavior of the adsorbed phase as the pressure increases. An analysis of isotherms over the whole coverage range showed that the heterogeneous surface character decreases with increasing number of adsorbed layers; that adsorption into the first and higher layers may be competitive, which produces a new isotherm resembling a mixed type II and III isotherm as proposed by Cerofolini and coworkers.

  6. Neural processing of emotional facial and semantic expressions in euthymic bipolar disorder (BD and its association with theory of mind (ToM.

    Directory of Open Access Journals (Sweden)

    Agustin Ibanez

    Full Text Available BACKGROUND: Adults with bipolar disorder (BD have cognitive impairments that affect face processing and social cognition. However, it remains unknown whether these deficits in euthymic BD have impaired brain markers of emotional processing. METHODOLOGY/PRINCIPAL FINDINGS: We recruited twenty six participants, 13 controls subjects with an equal number of euthymic BD participants. We used an event-related potential (ERP assessment of a dual valence task (DVT, in which faces (angry and happy, words (pleasant and unpleasant, and face-word simultaneous combinations are presented to test the effects of the stimulus type (face vs word and valence (positive vs. negative. All participants received clinical, neuropsychological and social cognition evaluations. ERP analysis revealed that both groups showed N170 modulation of stimulus type effects (face > word. BD patients exhibited reduced and enhanced N170 to facial and semantic valence, respectively. The neural source estimation of N170 was a posterior section of the fusiform gyrus (FG, including the face fusiform area (FFA. Neural generators of N170 for faces (FG and FFA were reduced in BD. In these patients, N170 modulation was associated with social cognition (theory of mind. CONCLUSIONS/SIGNIFICANCE: This is the first report of euthymic BD exhibiting abnormal N170 emotional discrimination associated with theory of mind impairments.

  7. Neural processing of emotional facial and semantic expressions in euthymic bipolar disorder (BD) and its association with theory of mind (ToM).

    Science.gov (United States)

    Ibanez, Agustin; Urquina, Hugo; Petroni, Agustín; Baez, Sandra; Lopez, Vladimir; do Nascimento, Micaela; Herrera, Eduar; Guex, Raphael; Hurtado, Esteban; Blenkmann, Alejandro; Beltrachini, Leandro; Gelormini, Carlos; Sigman, Mariano; Lischinsky, Alicia; Torralva, Teresa; Torrente, Fernando; Cetkovich, Marcelo; Manes, Facundo

    2012-01-01

    Adults with bipolar disorder (BD) have cognitive impairments that affect face processing and social cognition. However, it remains unknown whether these deficits in euthymic BD have impaired brain markers of emotional processing. We recruited twenty six participants, 13 controls subjects with an equal number of euthymic BD participants. We used an event-related potential (ERP) assessment of a dual valence task (DVT), in which faces (angry and happy), words (pleasant and unpleasant), and face-word simultaneous combinations are presented to test the effects of the stimulus type (face vs word) and valence (positive vs. negative). All participants received clinical, neuropsychological and social cognition evaluations. ERP analysis revealed that both groups showed N170 modulation of stimulus type effects (face > word). BD patients exhibited reduced and enhanced N170 to facial and semantic valence, respectively. The neural source estimation of N170 was a posterior section of the fusiform gyrus (FG), including the face fusiform area (FFA). Neural generators of N170 for faces (FG and FFA) were reduced in BD. In these patients, N170 modulation was associated with social cognition (theory of mind). This is the first report of euthymic BD exhibiting abnormal N170 emotional discrimination associated with theory of mind impairments.

  8. Rapid Detection of Staphylococcus aureus and Methicillin-Resistant S. aureus in Atopic Dermatitis by Using the BD Max StaphSR Assay.

    Science.gov (United States)

    Lee, Mi Kyung; Park, Kui Young; Jin, Taewon; Kim, Ju Hee; Seo, Seong Jun

    2017-07-01

    Eczematous lesions of atopic dermatitis (AD) patients are known to be a source of Staphylococcus aureus (SA) transmission and might be a reservoir for community-associated methicillin-resistant SA (MRSA). The BD Max StaphSR (BD-SR) is a fully automated, multiplex real-time PCR assay for the direct detection and differentiation of SA and MRSA from nasal swab samples. We evaluated the detection rates of SA and MRSA from skin lesions of outpatients with AD using the BD-SR assay, and determined the usefulness of the BD-SR assay. A total of 244 skin swab samples (skin lesions of 213 outpatients with AD and normal skin of 31 healthy controls) were tested directly by using the BD-SR assay. Of the 213 samples from patients with AD, 69 (32.4%) were positive for SA, 6 (8.7%) of which were positive for MRSA. Only 1 (3.2%) of 31 samples from healthy controls was positive for SA. The BD-SR assay is effective for the rapid detection of SA and MRSA from skin swab samples, which can provide important information for managing patients with AD and preventing the spread of MRSA. © The Korean Society for Laboratory Medicine.

  9. Meet the HENRYs: A hybrid focus group study of conspicuous luxury consumption in the social media context

    OpenAIRE

    Kennedy, G.; Bolat, Elvira

    2017-01-01

    Social media has created different dimension of consumers for luxury products, specifically the aspirational consumer who wishes to own a product, but for economic reasons cannot. In other words aspirational consumers use luxury brands to create value for themselves using social media to conspicuously consume without purchase. Aspirational consumers are mostly found among HENRYs (high earners, not rich yet). Studies around conspicuous consumption of luxury products as a result of digital tech...

  10. [Charles-Henri Fialon (1846-1933). Creator of the historical museum of the faculty of pharmacy of Paris].

    Science.gov (United States)

    Bzoura, Elie; Flahaut, Jean

    2004-01-01

    Charles-Henri Fialon stopped his pharmaceutical activities in 1892 and he devoted his time to artistic and historic works. He achieved an important collection of pharmaceutical pots and objects which he gave to the school of Pharmacy of Paris. These gifts were collected in a room named "Musée Fialon ". This museum was enlarged twice and presently is in the "Guillaume Valette" gallery. His content is described in this paper.

  11. Role of postoperative radiotherapy in the treatment of Merkel tumours: experience at the Henri Mondor Hospital on 21 cases

    International Nuclear Information System (INIS)

    Calitchi, E.; Pan, Q.; Diana, C.; Belkacemi, Y.; Lagrange, J.L.

    2010-01-01

    As Merkel tumour treatment modalities are still a matter of discussion, the authors report the experience gained on 21 patients in the radiotherapy department of the Henri Mondor Hospital between 1990 and 2005. The treatment always comprised a surgical exeresis followed by radiotherapy. The authors analyse the obtained results which confirm the interest of postoperative radiotherapy. The detailed analysis of modalities (radiation type, total dose, irradiation volume) allows an optimal irradiation scheme to be proposed. Short communication

  12. A pioneer of Australian paediatrics: Dr Henry Edward Brown (1858-1931).

    Science.gov (United States)

    Isles, Alan F; Roper, Peter; Pearn, John H

    2014-11-13

    The emergence of paediatrics as a specialty in Australian medicine dates from the last two decades of the 19th century. Among the pioneers of pre-Federation paediatrics, we include Dr Henry Edward Brown (1858-1931), an Irish-born physician and surgeon who became the first paediatrician to practise in the northern half of the Australian continent. In 1885, he was appointed as the medical superintendent of the Rockhampton Children's Hospital, itself a pioneer institution in the care of sick and injured children. Dr H.E. Brown also served as medical officer of health concurrently in three Queensland shires. He was a leader in the literary and sporting life of the busy port town of Rockhampton and a scholar and significant philanthropist in the domain of French literature. His life was and remains an exemplar of a class of pre-Federation paediatricians who established the ethos of clinical and societal service, which remains as a core feature of the speciality discipline of paediatrics in the 21st century. © 2014 The Authors. Journal of Paediatrics and Child Health © 2014 Paediatrics and Child Health Division (Royal Australasian College of Physicians).

  13. El urbanismo contra lo urbano. La ciudad y la vida urbana en Henri Lefebvre

    Directory of Open Access Journals (Sweden)

    Manuel Delgado Ruiz

    2018-01-01

    Full Text Available Henri Lefebvre coloca en el eje de su teoría sobre la vida urbana la oposición entre el espacio vivido por quienes lo usan o sueñan y el espacio abstracto que creen organizar los tecnócratas de la ciudad, que raramente reconocen hasta qué punto su “creatividad” está sometida a intereses privados o institucionales. Tras ese espacio hipotético sobre el que urbanistas y arquitectos trabajan no hay otra cosa que mera ideología, es decir, fantasma que recubre y disfraza las relaciones sociales reales de producción. Frente -o de espaldas- a ese orden espacial meramente teórico de los “especialistas”, lo que las ciudades conocen es la actividad constante o inminente de lo urbano, entendido como apoteosis y exacerbación de lo social, dinamismo siempre activado de acontecimientos y quehaceres sobre el que los “expertos” aplican planes y proyectos, pero del que no saben en realidad nada, acaso por lo cual pugnan por anularlo.

  14. Derivation of the MMPI-2-RF Henry-Heilbronner Index-r (HHI-r) scale.

    Science.gov (United States)

    Henry, George K; Heilbronner, Robert L; Algina, James; Kaya, Yasemin

    2013-01-01

    The 15-item Henry-Heilbronner Index (HHI) was published in 2006 as an MMPI-2 embedded measure of psychological response validity. When the MMPI-2 was revised in 2008 only 11 of the 15 original HHI items were retained on the MMPI-2-RF, prohibiting use of the HHI as an embedded validity indicator on the MMPI-2-RF. Using the original HHI sample an 11-item version of the HHI, the HHI-r, was evaluated for use as an embedded measure of psychological response validity for the MMPI-2-RF. The 11-item HHI-r was very similar to the HHI in classification accuracy. An HHI-r cutoff score of ≥7 was associated with a classification accuracy rate of 84.0%, good sensitivity (68.9%), and high specificity (93.2%) in identifying symptom exaggeration in personal injury and disability litigants versus non-litigating head-injured patients. These preliminary results suggest the HHI-r functions in a manner similar to the original HHI as a measure of psychological response validity, and may be used by psychologists and neuropsychologists as an MMPI-2-RF embedded validity indicator.

  15. Henry's Law vaporization studies and thermodynamics of einsteinium-253 metal dissolved in ytterbium

    International Nuclear Information System (INIS)

    Kleinschmidt, P.D.; Ward, J.W.; Matlack, G.M.; Haire, R.G.

    1984-01-01

    The cohesive energy of metallic einsteinium determines whether einsteinium is a trivalent or divalent metal. The enthalpy of sublimation, a measure of the cohesive energy, is calculated from the partial pressures of einsteinium over an alloy. The partial pressure of 253 Es has been measured over the range 470--870 K, using combined target and mass spectrometric Knudsen effusion techniques. An alloy was prepared with einsteinium dissolved in a ytterbium solvent to produce a very dilute solution. Partial pressure measurements on the alloy were amenable to the experimental technique and a data analysis using a Henry's law treatment of the data. Vapor pressure data are combined with an estimated crystal entropy S 0 298 and ΔC 0 /sub p/ for ytterbium, to produce enthalpy, entropy, and free energy functions from 298 to 1300 K. The vapor pressure of einsteinium in a dilute einsteinium--ytterbium alloy is described by the equation log P(atm) = -(6815 +- 216)/T+2.576 +- 0.337, from which we calculate for the enthalpy of sublimation of pure einsteinium ΔH 0 298 (second law) = 31.76 kcal/mol. The value of the enthalpy of sublimation is consistent with the conclusion that Es is a divalent metal

  16. Oestrogen and progesterone receptor assays in breast tumours. The Prince Henry's Hospital experience, 1983-1990.

    Science.gov (United States)

    Pearce, P T; Myles, K M; Funder, J W

    1993-08-16

    To present and analyse the results of eight years of experience (1983-1990) in breast tumour receptor analysis. All female primary breast tumour samples received (4683) were analysed for seasonal variation, patient age, relative risk index, oestrogen receptor (ER) and progesterone receptor (PR) status, ER and PR status as a function of age, ER and PR levels as a function of age, and ER and PR levels as a function of month of analysis. The assays were done at the Medical Research Centre, Prince Henry's Hospital, Melbourne, as a non-profit service to surgeons, oncologists and pathologists. The numbers of samples referred for assay increased progressively each year, from 473 in 1983 to 1097 in 1990, but the receptor status (ER +/-, PR +/-) appeared not to vary from year to year. ER+PR+ tumours were the most common in all age groups, steadily increasing from between 50% and 60% in premenopausal women to 70% or more in those aged over 80. In postmenopausal women, levels of ER in ER+ tumours were three times those in premenopausal women; PR levels in PR+ tumours, however, were bimodal, with higher levels in the age groups 35-49 and 70-89 years than in women aged 50-69 years. No significant seasonal variation was seen, and the overall patterns of receptor status are similar to those seen in Northern hemisphere studies.

  17. [Henri-Léonard Bertin and the development of agriculture in the Age of Enlightenment].

    Science.gov (United States)

    Pédro, Georges

    2012-05-01

    This meeting of the Committee on the History of Science and Epistemology takes place as we celebrate the 250th anniversary of the creation of the world's first veterinary schools, a major event among all those that, in the wake of the Physiocrat movement initiated by Quesnay and DuPont de Nemours, shaped the modernisation of agriculture in France during the 18th century. Henri-Léonard Bertin (1720-1792) was the impetus to the restructuring process. He was well aware that farming should not remain an activity that solely provides a livelihood for the population, but that it needed to be modernised, i.e. it should produce more, and better. His view was that agriculture could become a great source of riches for France and therefore, a true economic and even political force. He used the various official positions he occupied during that period (Intendant of Lyon (1754-1757), Controller General of Finances (1759-1763), Minister-Secretary of State for Agriculture (1763-1780) to initiate a number of reforms that brought about the modernisation of the kingdom's agricultural world. Copyright © 2012 Académie des sciences. Published by Elsevier SAS. All rights reserved.

  18. Reformation or Revolution? Herman Bavinck and Henri de Lubac on Nature and Grace

    Directory of Open Access Journals (Sweden)

    Parker Gregory W.

    2017-10-01

    Full Text Available Henri de Lubac’s treatment of the relationship between nature and grace will be critiqued by Herman Bavinck’s ‘grace restores nature’ theme. In two significant addresses, Bavinck critiqued a Roman Catholic approach to nature and grace. De Lubac’s influence upon Roman Catholic thinking addressing nature and grace occurred post-Bavinck and has altered Catholic thinking on the subject. Neo-Calvinist scholar, Wolter Huttinga admits that Bavinck and de Lubac offer similar critiques of Roman Catholicism (Huttinga 2014. The question remains then, do Bavinck’s critiques still hold? I propose that Bavinck’s account of grace restores nature still makes valid critiques of a post-Vatican II construction of nature and grace. The paper is broken into three sections: (1 an exploration of de Lubac’s nature and grace theme, (2 the framework of Bavinck’s ‘grace restores nature’ theme, and (3 a Bavinckian critique of de Lubac’s nature and grace theme.

  19. Henri Bergson y George Bernard Shaw: hábito, vida, muerte

    Directory of Open Access Journals (Sweden)

    Álvaro Cortina Urdampilleta

    2015-01-01

    Full Text Available Este artículo indaga en algunos aspectos de la antropología filosófica expuesta en la obra del francés Henri Bergson. Para ello, nos serviremos de la confrontación de su doctrina original con la de un bergsoniano sui generis, el intelectual y dramaturgo irlandés George Bernard Shaw. El Prefacio. A medio siglo infiel, de Shaw, incluido en su obra más ambiciosa, Vuelta a Matusalén. Un Pentateuco Metabiológico, de 1921, será el texto base con el que haremos dialogar a Bergson con este periférico bergsonismo. Tomaremos como hilo conductor la teoría sobre el hábito, en el contexto de la metafísica de la evolución de los seres orgánicos, y lo llevaremos hasta el concepto límite, que parece conciliar ambas posturas: la idea de muerte superable. Ni en Bergson ni en Shaw los hábitos (la Cultura forman parte integral de la esencia del hombre, y la muerte (cuestión en la que Bergson es mucho más elusivo juega en ellos un rol anfibio, entre Cultura y Naturaleza.

  20. Henry Hollingsworth Smith and His Bibliographical Index and Historical Record: The Beginning of American Surgical Historiography.

    Science.gov (United States)

    Rutkow, Ira

    2016-04-01

    To explore the details of Henry Hollingsworth Smith's (1815-1890) achievement as the first physician to organize in a systematic and chronologic manner the details of the history of surgery in America and prepare a register of men who performed surgical operations. The life of Smith, the earliest of the nation's surgeons to elucidate the history of American surgery, is little known. His boosting the image of the scalpel wielder helped shape the future of the craft, in particular, surgery's rise as a specialty and profession. An analysis of the published medical literature and unpublished documents relating to Smith and his work to document the history of American surgery. During the 1850 s, a time when surgery was not considered a separate branch of medicine but a mere technical mode of treatment, Smith's efforts in surgical history provided much needed encouragement to surgeons in their pursuit of professional recognition. Although Smith's accomplishment as the nation's first compiler of the history of American surgery has long been forgotten, his effort afforded the men who performed surgical operations their earliest measure of self-respect. As such, Smith belongs in America's pantheon of surgical heroes.

  1. Two-relaxation-time lattice Boltzmann method for the anisotropic dispersive Henry problem

    Science.gov (United States)

    Servan-Camas, Borja; Tsai, Frank T.-C.

    2010-02-01

    This study develops a lattice Boltzmann method (LBM) with a two-relaxation-time collision operator (TRT) to cope with anisotropic heterogeneous hydraulic conductivity and anisotropic velocity-dependent hydrodynamic dispersion in the saltwater intrusion problem. The directional-speed-of-sound technique is further developed to address anisotropic hydraulic conductivity and dispersion tensors. Forcing terms are introduced in the LBM to correct numerical errors that arise during the recovery procedure and to describe the sink/source terms in the flow and transport equations. In order to facilitate the LBM implementation, the forcing terms are combined with the equilibrium distribution functions (EDFs) to create pseudo-EDFs. This study performs linear stability analysis and derives LBM stability domains to solve the anisotropic advection-dispersion equation. The stability domains are used to select the time step at which the lattice Boltzmann method provides stable solutions to the numerical examples. The LBM was implemented for the anisotropic dispersive Henry problem with high ratios of longitudinal to transverse dispersivities, and the results compared well to the solutions in the work of Abarca et al. (2007).

  2. Henry Fayol’s 14 Principles of Management: Implications for Libraries and Information Centres

    Directory of Open Access Journals (Sweden)

    Uzuegbu, C. P.

    2015-06-01

    Full Text Available This paper focuses generally on the ‘fourteen principles of management’ by Henri Fayol. However, it specifically analyses their application to and implications for libraries and information centres. An extensive review of published works on management generally, and library management in particular, was conducted. This yielded vital insights on the original meaning and later modifications of these principles, as well as their application in the management of various organisations. Consequently, the strengths and weaknesses of these principles were examined to determine their suitability in libraries and information centres. Inferences, illustrations, and examples were drawn from both developed and developing countries which gives the paper a global perspective. Based on available literature, it was concluded that Fayol’s principles of management are as relevant to libraries as they are in other organisations. The paper, therefore, recommends that in addition to modifying some aspects to make these principles more responsive to the peculiar needs of libraries, further research should be undertaken to expand the breadth of these principles and ascertain their impacts on the management of information organisations.

  3. MgAl-Layered Double Hydroxide Solid Base Catalysts for Henry Reaction: A Green Protocol

    Directory of Open Access Journals (Sweden)

    Magda H. Abdellattif

    2018-03-01

    Full Text Available A series of MgAl-layered double hydroxide (MgAl-HT, the calcined form at 500 °C (MgAlOx, and the rehydrated one at 25 °C (MgAl-HT-RH were synthesized. Physicochemical properties of the catalysts were characterized by X-ray diffraction (XRD and scanning electron microscopy (SEM. Surface area of the as-synthesized, calcined, and rehydrated catalysts was determined by N2 physisorption at −196 °C. CO2 temperature-programmed desorption (CO2-TPD was applied to determine the basic sites of catalysts. The catalytic test reaction was carried out using benzaldehyde and their derivatives with nitromethane and their derivatives. The Henry products (1–15 were obtained in a very good yield using MgAl-HT-RH catalyst either by conventional method at 90 °C in liquid phase or under microwave irradiation method. The mesoporous structure and basic nature of the rehydrated solid catalyst were responsible for its superior catalytic efficiency. The robust nature was determined by using the same catalyst five times, where the product % yield was almost unchanged significantly.

  4. Hubble space telescope near-ultraviolet spectroscopy of the bright cemp-no star BD+44°493

    International Nuclear Information System (INIS)

    Placco, Vinicius M.; Beers, Timothy C.; Smith, Verne V.; Roederer, Ian U.; Cowan, John J.; Frebel, Anna; Filler, Dan; Ivans, Inese I.; Lawler, James E.; Schatz, Hendrik; Sneden, Christopher; Sobeck, Jennifer S.; Aoki, Wako

    2014-01-01

    We present an elemental-abundance analysis, in the near-ultraviolet (NUV) spectral range, for the extremely metal-poor star BD+44°493 a ninth magnitude subgiant with [Fe/H] =–3.8 and enhanced carbon, based on data acquired with the Space Telescope Imaging Spectrograph on the Hubble Space Telescope. This star is the brightest example of a class of objects that, unlike the great majority of carbon-enhanced metal-poor (CEMP) stars, does not exhibit over-abundances of heavy neutron-capture elements (CEMP-no). In this paper, we validate the abundance determinations for a number of species that were previously studied in the optical region, and obtain strong upper limits for beryllium and boron, as well as for neutron-capture elements from zirconium to platinum, many of which are not accessible from ground-based spectra. The boron upper limit we obtain for BD+44°493, log ε (B) <–0.70, the first such measurement for a CEMP star, is the lowest yet found for very and extremely metal-poor stars. In addition, we obtain even lower upper limits on the abundances of beryllium, log ε (Be) <–2.3, and lead, log ε (Pb) <–0.23 ([Pb/Fe] <+1.90), than those reported by previous analyses in the optical range. Taken together with the previously measured low abundance of lithium, the very low upper limits on Be and B suggest that BD+44°493 was formed at a very early time, and that it could well be a bona-fide second-generation star. Finally, the Pb upper limit strengthens the argument for non-s-process production of the heavy-element abundance patterns in CEMP-no stars.

  5. Suzaku Reveals Helium-burning Products in the X-Ray-emitting Planetary Nebula BD +30 3639

    Science.gov (United States)

    Murashima, M.; Kokubun, M.; Makishima, K.; Kotoku, J.; Murakami, H.; Matsushita, K.; Hayashida, K.; Arnaud, K.; Hamaguchi, K.; Matsumoto, H.

    2006-08-01

    BD +30 3639, the brightest planetary nebula at X-ray energies, was observed with Suzaku, an X-ray observatory launched on 2005 July 10. Using the X-ray Imaging Spectrometer, the K lines from C VI, O VII, and O VIII were resolved for the first time, and the C/O, N/O, and Ne/O abundance ratios were determined. The C/O and Ne/O abundance ratios exceed the solar value by factors of at least 30 and 5, respectively. These results indicate that the X-rays are emitted mainly by helium-shell-burning products.

  6. $B_{d} \\to K^{*0}\\mu^{+}\\mu^{-}$ as a lab for discovering new physics at LHCb

    CERN Document Server

    Skottowe, Hugh

    2010-01-01

    The analysis of the penguin decay Bd->K*MuMu at LHCb can act as a laboratory for the discovery and understanding of new physics. Through the Operator Product Expansion, the decay kinematics are well understood in both the Standard Model and in a large range of new physics scenarios. The theoretical errors from QCD effects can be characterized and a set of observables have been derived which minimise their influence in measurements. We will describe how these measurements can be made in LHCb with special emphasis on what can be done with a first run of the LHC with a few hundred pb-1 of integrated luminosity.

  7. $B_d \\to K^*\\mu\\mu$ as a lab for discovering new physics at LHCb

    CERN Document Server

    Skottowe, H

    2010-01-01

    The analysis of the penguin decay $B_d \\to K^*\\mu\\mu$ at LHCb can act as a laboratory for the discovery and understanding of new physics. Through the Operator Product Expansion, the decay kinematics are well understood in both the Standard Model and in a large range of new physics scenarios. The theoretical errors from QCD effects can be characterized and a set of observables have been derived which minimise their influence in measurements. We will describe how these measurements can be made in LHCb with special emphasis on what can be done with a first run of the LHC with a few hundred pb$^{-1}$ of integrated luminosity.

  8. Experimental investigations concerning the three particle reaction 19B(d,3α) at 360 keV

    International Nuclear Information System (INIS)

    Nocken, U.

    1976-01-01

    In this paper a complete energy angular correlation measurement of the three-particle reaction 10 B(d,3α) with an incident energy of Esub(d) = 360 keV is reported. By the measurement of coincidence events in two detectors complanar to the incident beam under 24 different angles, the 'Dalitz-plane' is covered in a wide region. An exact theory of three-particle reactions with compound nuclei in the final state does not exist, therefore three wellknown model theories are used for comparison. (orig./WL) [de

  9. Independent assessment of the TRAC-BD1/MOD1 computer code at the Idaho National Engineering Laboratory

    International Nuclear Information System (INIS)

    Wilson, G.E.; Charboneau, B.L.; Dallman, R.J.; Kullberg, C.M.; Wagner, K.C.; Wheatley, P.D.

    1984-01-01

    Under auspices of the United States Nuclear Regulatory Commission, their primary boiling water reactor safety analysis code (TRAC-BWR) is being assessed with simulations of a wide range of experimental data. The FY-1984 assessment activities were associated with the latest version (TRAC-BD1/MOD1) of this code. Typical results of the assessment studies are given. Conclusions formulated from these results are presented. These calculations relate to the overall applicability of the current code to safety analysis, and to future work which would further enhance the code's quality and ease of use

  10. Jet creation in post-AGB binaries: the circum-companion accretion disk around BD+46°442

    Science.gov (United States)

    Bollen, Dylan; Van Winckel, Hans; Kamath, Devika

    2017-11-01

    Aims: We aim at describing and understanding binary interaction processes in systems with very evolved companions. Here, we focus on understanding the origin and determining the properties of the high-velocity outflow observed in one such system. Methods: We present a quantitative analysis of BD+46°442, a post-AGB binary that shows active mass transfer that leads to the creation of a disk-driven outflow or jet. We obtained high-resolution optical spectra from the HERMES spectrograph, mounted on the 1.2 m Flemish Mercator Telescope. By performing a time-series analysis of the Hα profile, we identified the different components of the system. We deduced the jet geometry by comparing the orbital phased data with our jet model. In order to image the accretion disk around the companion of BD+46°442, we applied the technique of Doppler tomography. Results: The orbital phase-dependent variations in the Hα profile can be related to an accretion disk around the companion, from which a high-velocity outflow or jet is launched. Our model shows that there is a clear correlation between the inclination angle and the jet opening angle. The latitudinally dependent velocity structure of our jet model shows a good correspondence to the data, with outflow velocities higher than at least 400 km s-1. The intensity peak in the Doppler map might be partly caused by a hot spot in the disk, or by a larger asymmetrical structure in the disk. Conclusions: We show that BD+46°442 is a result of a binary interaction channel. The origin of the fast outflow in this system might be to a gaseous disk around the secondary component, which is most likely a main-sequence star. Our analysis suggests that the outflow has a rather wide opening angle and is not strongly collimated. Our time-resolved spectral monitoring reveals the launching site of the jet in the binary BD+46°442. Similar orbital phase-dependent Hα profiles are commonly observed in post-AGB binaries. Post-AGB binaries provide ideal

  11. Henry's law and accumulation of weak source for crust-derived helium: A case study of Weihe Basin, China

    Directory of Open Access Journals (Sweden)

    Yuhong Li

    2017-12-01

    Full Text Available Crust-derived helium is generated from the radioactive decay of uranium, thorium and other radioactive elements in geological bodies. Compared with conventional natural gas, helium is a typical weak source gas as a result of extremely slow generation rate and absence of helium-generating peak. It is associated with methane or carbon dioxide reservoirs frequently and related to groundwater closely. Helium can meet the industry standard with 0.1% in volume fraction. In order to study the accumulation mechanism of helium, the previous research on Henry's coefficient and solubility of helium, nitrogen and methane are summarized and the key roles of Henry's Law in the helium migration, accumulation and preservation are discussed by simulating calculation taking Weihe Basin as an example. According to the Law, the gas solubility in dilute solution is controlled by the gas partial pressure and the Henry's coefficient. Compared with the carrier gases, the Henry's constant of helium is high, with striking difference at low and high temperature. In addition, the helium partial pressure is greatly different in helium source rocks and gas reservoirs, resulting in the great differences of helium solubility in the two places. The accumulation progresses are as follows. Firstly, helium can dissolve into water and migrate out of helium source rocks due to the high helium solubility, which is caused by high helium partial pressure and high temperature in source rock. Secondly, when dissolved helium is transported to the shallow gas reservoir, it is prone to be out of solution and into reservoir due to the extremely low partial pressure and low temperature. Meanwhile part of carrier gases dissolves into water, as if helium is “replaced” out. Furthermore, the low concentration funnel of dissolved helium is formed near the gas reservoir, then other dissolved helium continues to migrate towards the gas reservoir, which greatly improves the helium accumulation

  12. The cDNA Cloning and Sequencing of Reindeer β-defensin reBD-1%驯鹿β-防御素reBD-1 cDNA的克隆及序列分析

    Institute of Scientific and Technical Information of China (English)

    杨银凤; 赵艳芳; 余兴帮; 郝永峰

    2006-01-01

    从驯鹿舌黏膜上皮组织中提取总RNA,采用RT-PCR技术扩增出reBD-1的cDNA,并重组到pBlueselect T载体,经限制性内切酶谱分析和DNA序列测定,证实所克隆的reBD-1的cDNA为β-防御素,因为该cDNA包含由192个碱基组成的开放读码框(ORF),该ORF编码64个氨基酸残基的前原防御素,该前原防御素含有β-防御素特征性结构即6个在特定位置上的保守半胱氨酸残基.驯鹿β-防御素属首次发现,为更好地了解驯鹿黏膜防御机制有很大的帮助.

  13. Improved management of SG BD demineralizer for reduced generation of low-level radioactive spent resin in Korean nuclear power plants

    International Nuclear Information System (INIS)

    Rhee, I.; Cho, D.; Yeon, J.

    2003-01-01

    Most nuclear power plants in Korea have adopted Ethanolamine(ETA) as a secondary pH control agent to increase the pH at the liquid phase, which may reduce the corrosion in steam generator tubes and moisture separator/reheat system. Along with its beneficial effect of SG protection from corrosion and degradation, the replacement of ammonia with ETA causes the increased generation of spent resin and the reduced run time of demineralizer in steam generator blowdown(SG BD) system. The composition ratio of cation- to anion- exchange resin in SG BD mixed bed should be increased in the ETA chemistry environment to meet the ratio of cation to anion in the aqueous solution, which results in the simultaneous exhaustion of cation and anion exchange resins. The utilization rate of mixed bed is greatest at the cation-to-anion ratio of 95:1 on the theoretical equivalent basis in the solution, but practically highest at that of 22:1 due to the possible inhomogeneous distribution of cation and anion exchange resins in SG BD bed. The run time of the bed could be extended by 30% such that, at that much, the purchase cost of new resin is saved and the production rate of spent resin is reduced. The guideline on the replacement of resin in SG BD bed is not necessary to secure the removal of radioactive particles without the leakage of the primary coolant into the secondary side since all the radioactive ions can be eliminated by SG BD bed with the sufficient time. They are retained during more than one month after their ingress into the SG BD bed without leakage. With the reduced replacement, thus, the SG BD spent resin that comprises 65% of low-level radioactive solid waste can be much cut down

  14. Bd on the beach: high prevalence of Batrachochytrium dendrobatidis in the lowland forests of Gorgona Island (Colombia, South America).

    Science.gov (United States)

    Flechas, Sandra Victoria; Sarmiento, Carolina; Amézquita, Adolfo

    2012-09-01

    The amphibian chytrid fungus, Batrachochytrium dendrobatidis, Bd, has been implicated in the decimation and extinction of many amphibian populations worldwide, especially at mid and high elevations. Recent studies have demonstrated the presence of the pathogen in the lowlands from Australia and Central America. We extend here its elevational range by demonstrating its presence at the sea level, in the lowland forests of Gorgona Island, off the Pacific coast of Colombia. We conducted two field surveys, separated by four years, and diagnosed Bd by performing polymerase chain reactions on swab samples from the skin of five amphibian species. All species, including the Critically Endangered Atelopus elegans, tested positive for the pathogen, with prevalences between 3.9 % in A. elegans (in 2010) and 52 % in Pristimantis achatinus. Clinical signs of chytridiomycosis were not detected in any species. To our knowledge, this is the first report of B. dendrobatidis in tropical lowlands at sea level, where temperatures may exceed optimal growth temperatures of this pathogen. This finding highlights the need to understand the mechanisms allowing the interaction between frogs and pathogen in lowland ecosystems.

  15. High-resolution 8-13 micron imaging of the planetary nebulae BD + 30 deg 3639 and NGC 6572

    International Nuclear Information System (INIS)

    Hora, J.L.; Hoffmann, W.F.; Deutsch, L.K.; Fazio, G.G.

    1990-01-01

    High-resolution midinfrared images of the planetary nebulae BD + 30 deg 3639 and NGC 6572 are presented at 8.3, 8.7, 9.8, 11.2, and 12.4 microns. Analysis of the maps of BD + 30 deg 3639 supports a model in which the infrared emission originates from two spatially distinct components, one which is responsible for the continuum radiation at 8-12 microns and the other which produces the emission-line features. The NGC 6572 images provides evidence for a previously undetected 11.2 micron UIR emission feature. Comparison with radio continuum maps indicates that the distribution of dust is similar to the distribution of ionized gas in each nebula. Various models of source morphology are also investigated. The planetary nebulae DB + 30 deg 3639 and NGC 6572 can be modeled by an optically thin cylinder or a prolate ellipsoid with enhanced equatorial emission. These models reproduce well the general features of the nebula, such as the bipolar lobes of emission and the ring structure. 67 refs

  16. The "Cool Algol" BD+05 706 : Photometric observations of a new eclipsing double-lined spectroscopic binary

    Science.gov (United States)

    Marschall, L. A.; Torres, G.; Neuhauser, R.

    1998-05-01

    BVRI Observations of the star BD+05 706, carried out between January, 1997, and April 1998 using the 0.4m reflector and Photometrics CCD camera at the Gettysburg College Observatory, show that the star is an eclipsing binary system with a light curve characteristic of a class of semi-detached binaries known as the "cool Algols". These results are in good agreement with the previous report of BD+05 706 as a cool Algol by Torres, Neuhauser, and Wichmann,(Astron. J., 115, May 1998) who based their classification on the strong X-ray emission detected by Rosat and on a series of spectroscopic observations of the radial velocities of both components of the system obtained at the Oak Ridge Observatory, the Fred L. Whipple Observatory, and the Multiple Mirror Telescope. Only 10 other examples of cool Algols are known, and the current photometric light curve, together with the radial velocity curves obtained previously, allows us to derive a complete solution for the physical parameters of each component, providing important constraints on models for these interesting systems.

  17. [The materialistic strategy of Henry Howard, a Québec alienist (1815-1887).].

    Science.gov (United States)

    Fugère, A

    1978-01-01

    At the end of the 19th century, Henry Howard appeared as the first Quebec "aliéniste" to attempt to develop an inclusive theoretical treatise on the question of madness. Why this sudden upheaval ? There existed numerous european theories ; that might have sufficed. The author attempts to show the multiple connections of this theoretical pro-lect to the socio-political problems of québécois society. Howard tries, from the perspective of the theory which he elaborates, to intervene in the major discussions affecting Quebec: ultra montanism, the problem of universal compusory education, public morality. At a more professional level he attempts to intervene in the legal dispute opposing judicial and medical competence in the cases of insanity pleas, as well as in the question of the scientific and social status of the "aliéniste". The involvement in these struggles manifests itself in Howard's treatise as much at the level of the concepts themselves, and their architecture, as at the thematic level and in the applications which he naturally draws. It is not onty external and contingent but works on the text from the inside as well. The article attempts to suggest that at the very moment that the treatise on the alienated-which would become the "science" that we know today- seeks to structure itself into a theory, it cannot break its attachment to its determining social context and that, ignoring its ideological role it, in truth, succeeds only in creating illusion and the impression of a progressive process, all the while being circumstantial and having a verted interest.

  18. The Soundscapes of Henry Mayhew Urban Ethnography and Technologies of Transcription

    Directory of Open Access Journals (Sweden)

    Helen Groth

    2012-11-01

    Full Text Available Contemporary reviewers of London Labour and the London Poor were quick to label as inauthentic both the engraved re-mediations of John Beard’s daguerreotype portraits and Henry Mayhew’s transcription of the voices of London’s street habitués. Mayhew’s literal mediations of patter, slang and speech rhythms were the subject of particular scrutiny.  As one critic acerbically observed: ‘The photographs no doubt are accurate enough, but those dialogues smell of the footlights.’  Such criticisms strike at the core of Mayhew’s commitment to the technologies of faithful mimesis and the mediation of an authentic experience of the everyday lives of London’s wandering tribes.  Sound bites of characteristic speech serve as titles for many of the engraved reproductions of John Beard’s daguerreotypes reinforcing the analogy between visual and textual modes of transcription.  Likewise Mayhew insists that his various re-enactments of the multi-sensorial experience of elbowing through London’s crowded marketplaces and streets are ‘unvarnished’ transparent mediations of its various sounds and voices.  Central to Mayhew’s enterprise is the commitment to recording and capturing a dying way of life.  Now silenced voices are captured and remediated to ‘shock’ and teach through the ‘heart’ to use Mayhew’s terminology.  This paper will reconsider Mayhew’s investment in the power of sympathetic communication in the context of broader transformations in mid-nineteenth century conceptions of the media as a conduit for information rather than as a mechanism of persuasion.

  19. Reinvestigation of the Henry's law constant for hydrogen peroxide with temperature and acidity variation.

    Science.gov (United States)

    Huang, Daoming; Chen, Zhongming

    2010-01-01

    Hydrogen peroxide is not only an important oxidant in itself; it also serves as both sink and temporary reservoir for other important oxidants including HOx (OH and HO2) radicals and O3 in the atmosphere. Its partitioning between gas and aqueous phases in the atmosphere, usually described by its Henry's law constant (K(H)), significantly influences its role in atmospheric processes. Large discrepancies between the K(H) values reported in previous work, however, have created uncertainty for atmospheric modelers. Based on our newly developed online instrumentation, we have re-determined the temperature and acidity dependence of K(H) for hydrogen peroxide at an air pressure of (0.960 +/- 0.013) atm (1 atm = 1.01325 x 10(5) Pa). The results indicated that the temperature dependence of K(H) for hydrogen peroxide fits to the Van't Hoff equation form, expressed as lnK(H) = a/T - b, and a = -deltaH/R, where K(H) is in M/atm (M is mol/L), T is in degrees Kelvin, R is the ideal gas constant, and deltaH is the standard heat of solution. For acidity dependence, results demonstrated that the K(H) value of hydrogen peroxide appeared to have no obvious dependence on decreasing pH level (from pH 7 to pH 1). Combining the dependence of both temperature and acidity, the obtained a and b were 7024 +/- 138 and 11.97 +/- 0.48, respectively, deltaH was (58.40 +/- 1.15) kJ/(K x mol), and the uncertainties represent sigma. Our determined K(H) values for hydrogen peroxide will therefore be of great use in atmospheric models.

  20. On the article by Henri Poincare' open-quotes on the dynamics of the electronclose quotes

    International Nuclear Information System (INIS)

    Logunov, A.A.

    1996-01-01

    The first complete translations into English are presented of two articles written by the outstanding French scientist Henri Poincare and submitted by him in 1905 under the common title of open-quotes Sur la dynamique de l'electronclose quotes to different journals. In the present edition of these articles by H. Poincare, modern notation is used, and the articles are accompanied by comments written by A.A. Logunov. The author of the comments explains the profound physical meaning and essential novelty of the particular points and relationships established by Poincare. Such explanations are often interspersed with quotations from earlier articles by Poincare, thus clearly indicating that the main initial points of the new theory were put forward by the French scientist much before 1905, while certain concepts like 'local' time and the arbitrariness of simultaneity were given a clear explanation from the point of view of physical meaning. A.A. Logunov's book, presenting the works of Poincare on the development of relativity theory, has had quite a high success among specialists interested in the history of physics, and since 1984 it has been published in Russian three times. The present English-language edition is identical to the last 1988 Russian edition, and is dedicated to the 90th anniversary of Poincare's articles 'On the Dynamics of the Electron'. In preparing the English text, fragments were used of the translation of the long article by H.Poincare published in the book by Professor C.W. Kilmister from King's College in London/Special Theory of Relativity, Pergamon Press, New York, 1970/

  1. Exercise Capacity and the Obesity Paradox in Heart Failure: The FIT (Henry Ford Exercise Testing) Project.

    Science.gov (United States)

    McAuley, Paul A; Keteyian, Steven J; Brawner, Clinton A; Dardari, Zeina A; Al Rifai, Mahmoud; Ehrman, Jonathan K; Al-Mallah, Mouaz H; Whelton, Seamus P; Blaha, Michael J

    2018-05-03

    To assess the influence of exercise capacity and body mass index (BMI) on 10-year mortality in patients with heart failure (HF) and to synthesize these results with those of previous studies. This large biracial sample included 774 men and women (mean age, 60±13 years; 372 [48%] black) with a baseline diagnosis of HF from the Henry Ford Exercise Testing (FIT) Project. All patients completed a symptom-limited maximal treadmill stress test from January 1, 1991, through May 31, 2009. Patients were grouped by World Health Organization BMI categories for Kaplan-Meier survival analyses and stratified by exercise capacity (<4 and ≥4 metabolic equivalents [METs] of task). Associations of BMI and exercise capacity with all-cause mortality were assessed using multivariable-adjusted Cox proportional hazards models. During a mean follow-up of 10.1±4.6 years, 380 patients (49%) died. Kaplan-Meier survival plots revealed a significant positive association between BMI category and survival for exercise capacity less than 4 METs (log-rank, P=.05), but not greater than or equal to 4 METs (P=.76). In the multivariable-adjusted models, exercise capacity (per 1 MET) was inversely associated, but BMI was not associated, with all-cause mortality (hazard ratio, 0.89; 95% CI, 0.85-0.94; P<.001 and hazard ratio, 0.99; 95% CI, 0.97-1.01; P=.16, respectively). Maximal exercise capacity modified the relationship between BMI and long-term survival in patients with HF, upholding the presence of an exercise capacity-obesity paradox dichotomy as observed over the short-term in previous studies. Copyright © 2018 Mayo Foundation for Medical Education and Research. Published by Elsevier Inc. All rights reserved.

  2. Le corps dans l’espace architectural. Le Corbusier, Claude Parent et Henri Gaudin

    Directory of Open Access Journals (Sweden)

    Julie Cattant

    2016-12-01

    Full Text Available Le premier geste de l’espace architectural est d’accueillir nos corps humains. En leur offrant un espacement à habiter, il leur permet de s’abriter, de se mouvoir et de se rencontrer. L’homme et l’architecture s’affectent l’un l’autre. Nombreux sont les architectes qui interrogent cette coexistence car, renouveler la pensée de l’espace nécessite de reconsidérer le corps humain. L’étude des relations entre le corps et l’espace chez trois architectes français sera l’occasion d’évoquer les écarts et les convergences entre l’homme et l’architecture. L’œuvre de Le Corbusier, protagoniste du mouvement moderne, maintient ainsi une distance entre un corps machinisé et un espace idéal. Marquée par un mode de pensée dualiste, l’architecture de Le Corbusier annonce toutefois son propre dépassement, dépassement que Claude Parent et Henri Gaudin opèreront par la suite à leur manière, le premier en introduisant l’oblique et la déstabilisation du corps, le second en transgressant la limite de l’espace et du corps pour envisager leur porosité réciproque. Finalement, c’est la manière dont l’homme appréhende l’espace avec son corps qui est questionnée par ces trois architectes, de la prégnance du visuel à son évincement.

  3. Developing a framework for digital objects in the Big Data to Knowledge (BD2K) commons: Report from the Commons Framework Pilots workshop.

    Science.gov (United States)

    Jagodnik, Kathleen M; Koplev, Simon; Jenkins, Sherry L; Ohno-Machado, Lucila; Paten, Benedict; Schurer, Stephan C; Dumontier, Michel; Verborgh, Ruben; Bui, Alex; Ping, Peipei; McKenna, Neil J; Madduri, Ravi; Pillai, Ajay; Ma'ayan, Avi

    2017-07-01

    The volume and diversity of data in biomedical research have been rapidly increasing in recent years. While such data hold significant promise for accelerating discovery, their use entails many challenges including: the need for adequate computational infrastructure, secure processes for data sharing and access, tools that allow researchers to find and integrate diverse datasets, and standardized methods of analysis. These are just some elements of a complex ecosystem that needs to be built to support the rapid accumulation of these data. The NIH Big Data to Knowledge (BD2K) initiative aims to facilitate digitally enabled biomedical research. Within the BD2K framework, the Commons initiative is intended to establish a virtual environment that will facilitate the use, interoperability, and discoverability of shared digital objects used for research. The BD2K Commons Framework Pilots Working Group (CFPWG) was established to clarify goals and work on pilot projects that address existing gaps toward realizing the vision of the BD2K Commons. This report reviews highlights from a two-day meeting involving the BD2K CFPWG to provide insights on trends and considerations in advancing Big Data science for biomedical research in the United States. Copyright © 2017 Elsevier Inc. All rights reserved.

  4. Prokaryotic Expression of Reindeer β-defensin-1 (reBD-1) Gene and Bioactivity Identification of the Recombinant Protein%驯鹿β-防御素-1(reBD-1)基因的原核表达及蛋白活性的鉴定

    Institute of Scientific and Technical Information of China (English)

    苏丽娜; 杨银凤; 景岚; 曹贵方

    2011-01-01

    The aim of this experiment was to construct prokaryotic expression vector of reindeer β-defensin-l(reBD-l), induce the expression of reBD-1 fusion protein in E. Coli, and evaluate the bioactivity of the expression products. The prepro-peptide of reBD-1 was amplified by RT-PCR. The mature peptide of encoding reBD-1 was amplified from recombinant cloning vector PMD19T/ reBD-1, and then cloned into pET-32a (+ ), in which reBD-1 fusion protein expression was induced by IPTG in E. Coli BL2KDE3). The expressed product was further cultured and purified for experiment of bacteriostasis in vitro. The results showed that the amplified products of prepro-peptide and mature peptide were 215 and 138 bp, respectively, and the homology of the sequences of the targeted gene and reBD-1 mRNA was up to 100%. The molecular weight of fusion proteins of prepro-peptide and mature peptide were 28 and 24 ku. The agar diffusion method has demonstrated that 0. 08 mg · mL-1 purified mature peptide protein has obvious antimicrobial activity against S. Aureus and E. Coli. From the results we can conclude that the prepro-peptide and mature peptides have high expression level in E. Coli, and the mature peptide has resistance to both Gram negative and Gram positive bacteria.%旨在构建驯鹿β防御素-1(Reindeerβ-defensin-1,reBD-1)基因的原核表达载体pET-32a(+ )/reBD-1,诱导reBD-1融合蛋白在大肠杆菌中表达,并对其表达产物的生物学活性进行评价.利用RT-PCR技术扩增reBD-1前原肽.从重组克隆载体PMD19T/reBD-1中扩增reBD-1成熟肽编码基因,并克隆入pET-32a(+)中,在大肠杆菌BL21 (DE3)中用IPTG诱导表达reBD-1融合蛋白.表达的融合蛋白扩大培养,进一步纯化后进行体外抑菌试验.结果表明,reBD-1前原肽和成熟肽扩增产物大小分别为215和138 bp,目的基因的序列与驯鹿防御素-1 mRNA序列同源性为100%.前原肽和成熟肽融合蛋白分子量分别为28和24 ku.利用琼脂糖扩散法表明,0

  5. Cloning and analysis of the full-length cDNA of reindeer β-defensin caBD-1%驯鹿β-防御素reBD-1全长cDNA的克隆及序列分析

    Institute of Scientific and Technical Information of China (English)

    杨银凤; 郝永峰; 赵艳芳; 余兴帮; 都格尔斯仁

    2008-01-01

    为了获得驯鹿β-防御素reBD-1全长cDNA序列,根据已获得的reBD-1 cDNA的已知序列设计1条序列特异性引物作为上游引物,反转录引物中的部分序列即3′接舍器引物作为下游引物,克隆reBD-1 cDNA的3′末端序列.另外,采用反向嵌套PCR RACE法,根据reBD-1 cDNA的已知序列,设计1条5′末端磷酸化的特异性反转录引物和2对特异性反向嵌套PCR引物,首先进行反转录(RT),然后将mRNA反转录成的cDNA进行环化,最后进行反向嵌套巢式PCR,克隆reBD-1 cDNA的5′末端序列.结果成功的克隆出了reBD-1 cDNA的3′和5′末端序列,从而得到372 bp的reBD-1 cDNA全序列,其中包含44 bp 5′非翻译区(UTR)、192 bp的开放读码框(ORF)、终止密码子TAA、118 bp的3′UTR和poly(A)15.reBD-1 cDNA全序列的获得为进一步研究其基因结构、基因表达和基因功能奠定了基础.

  6. Beyond the Historical Record? Henry James in “The Master at St. Bartholomew’s Hospital

    Directory of Open Access Journals (Sweden)

    Elena Ogliari

    2018-02-01

    Full Text Available The article analyses the short-story “The Master at St Bartholomew’s Hospital 1914–1916” by Joyce Carol Oates (2007 in the broader context of the Jamesian biofiction, a series of novels and tales featuring Henry James as their protagonist. The addition of the prefix “bio-” to “fiction” points out the hybrid nature of these texts, which are a melange of biography, autobiography, criticism and fiction. Oates’s story not only epitomizes this hybridity, but it also proves to be an exploration of the potentiality of this subgenre to penetrate the mystery surrounding James’s persona and saturate the lacunae in his biography by resorting to what David Lodge defined as “the novelist’s licence”. The short-story is yet another evidence of Oates’s fascination with the unsaid in James’s life and prose, because it revolves around the silence into which he sank at the outbreak of the Great War, when he did not write anything in his pocket diaries for three months. In an attempt to go beyond the limits of the historical record, Oates gives insights into the mind of the author by depicting a Henry James in crisis – nagged by doubts about his artistic legacy – in an atmosphere of uncertainty enhanced by a complex intertextual play. The result is ‘a Henry James’ slightly divergent from the historical one: thus, the tale advocates the inaccessibility of the private life of a real individual. Nonetheless, the acknowledgement of this limit spurs the celebration of fictional imagination.

  7. Banque centrale, taux de l'escompte et politique monétaire chez Henry Thornton (1760-1815).

    OpenAIRE

    Mésonnier, J-S.

    2002-01-01

    Henry Thornton (1760-1815), whose major work - An Enquiry into the Nature and Effects of the Paper Credit of Great Britain - is celebrating its bicentennary in 2002, is considered today to be one of the most prominent classical monetary economist, in particular with regard to its seminal contribution to the theory of the lender of last resort. However, Thornton's original views about the rate of interest on bank credit have barely been commented so far. In this paper, we endeavour to link the...

  8. Abraham Pais Prize for History of Physics Talk: Henry Cavendish, John Michell, Weighing the Stars

    Science.gov (United States)

    McCormmach, Russell

    2010-03-01

    This talk is about an interaction between two 18th-century natural philosophers (physical scientists), Henry Cavendish and John Michell, and its most important outcome, the experiment of weighing the world (their name for it) using a torsion balance (our name for it). Michell was the most inventive of the 18th century English natural philosophers, and Cavendish was the first of his countrymen to possess abilities at all comparable with Newton's. By their interests and skills, they were drawn to one another. Both were universal natural philosophers, equally adept at building scientific instruments, performing experiments, constructing theory, and using mathematics; both had a penchant for exacting, quantitative work. Both also had fitful habits of publication, which did not begin to reveal the range of their work, to the mystification of later scientists and historians. Late in life, Cavendish and Michell turned their attention to the force that Newton had examined most completely, a singular triumph of his natural philosophy, the force of universal gravitation. Over the course of the 18th century, abundant evidence of attraction had been gathered from the motions of the earth, moon, planets, and comets, phenomena which span the intermediate range of masses, sizes, and distances. But in three domains of experience, involving the extreme upper and lower limits of masses and dimensions, the universality of gravitation remained an article of faith. These were the gravity of the ``fixed'' stars, the mutual attraction of terrestrial bodies, and the gravitation of light and other special substances. Michell took on himself the task of deducing observable consequences from each of these prospective instances of universal gravitation. Cavendish encouraged Michell, and he followed up the resulting observational and experimental questions. The experiment of weighing the world was the last experiment Mitchell planned and the last experiment Cavendish published. The capstone of

  9. Controls on sediment cover in bedrock-alluvial channels of the Henry Mountains, Utah

    Science.gov (United States)

    Hodge, R. A.; Yager, E.; Johnson, J. P.; Tranmer, A.

    2017-12-01

    The location and extent of sediment cover in bedrock-alluvial channels influences sediment transport rates, channel incision and instream ecology. However, factors affecting sediment cover and how it responds to changes in relative sediment supply have rarely been quantitatively evaluated in field settings. Using field surveys and SFM analysis of channel reach topography, we quantified sediment cover and channel properties including slope, width, grain size distributions, and bedrock and alluvial roughness in North Wash and Chelada Creek in the Henry Mountains, Utah. Along reaches where upstream sediment supply does not appear to be restricted, we find that the fraction of local bedrock exposure increases as a function of local relative transport capacity . In a downstream section of Chelada Creek, decadal-scale sediment supply has been restricted by an upstream culvert that has caused a backwater effect and corresponding upstream deposition. In this section, alluvial cover is uncorrelated with local stream power. To test the impact of relative sediment supply on sediment cover, a 1D sediment transport model was used to predict the equilibrium sediment cover in Chelada Creek under varying flow and sediment supply conditions. Sediment transport in each model section was predicted using the partial cover model of Johnson (2015), which accounts for differences in bedrock and alluvial roughness on critical shear stress and flow resistance. Model runs in which sediment supply was approximately equal to mean transport capacity produced a pattern of sediment cover which best matched the field observations upstream of the culvert. However, runs where sediment supply was under-capacity produced the pattern most similar to field observations downstream of the culvert, consistent with our field-based interpretations. Model results were insensitive to initial sediment cover, and equilibrium was relatively quickly reached, suggesting that the channel is responsive to changes in

  10. [Henri Ellenberger, Henri Ey and the Traité de Psychiatrie in the "Encyclopédie Médico-Chirurgicale": an American career under the auspices of the "Evolution Psychiatrique"].

    Science.gov (United States)

    Delille, Emmanuel

    2006-01-01

    Henri Ellenberger, psychiatrist and historian, experienced a decisive period in his career in the early fifties of the last century. Educated in France, intern at Sainte-Anne Hospital, he was working in Switzerland after the war and then tried to move to the United States. It was during his participation in the French group "l'Evolution Psychiatrique" that he happened to contribute to the treatise of psychiatry (1955) of the French medical and surgical encyclopaedia ("EMC") and organise an observation trip to the United States. He was supported at that time by Henri Ey, key figure of French psychiatry. While going back to his career, we would like to emphasise on his comments about the "Psychotherapy of schizophrenia". Even though later Ellenberger became a well-known researcher in North America, it is more a question for us to discuss the scientific ambition he had in this particular context of a French learned society as a member of "l'Evolution Psychiatrique" and as a psychiatrist formerly intern from the "Hôpitaux psychiatriques de la Seine" (Parisian district).

  11. Contribuições de Henri Wallon à relação cognição e afetividade na educação Contributions from Henri Wallon to the relationship between cognition and affectivity in education

    Directory of Open Access Journals (Sweden)

    Aurino Lima Ferreira

    2010-01-01

    Full Text Available O presente artigo versa sobre as contribuições de Henri Wallon à relação cognição e afetividade na educação. Situa e define os complexos afetivos e cognitivos na teoria waloniana e destaca a noção de pessoa engajada como síntese fundamental para o entendimento da relação entre afetividade e cognição no campo educacional. Busca ainda apontar a importância da visão dialética e humanista da pessoa completa de Wallon para as práticas educacionais e retoma a ideia de "circularidade fundamental" de Francisco Varela para atualizar a visão de Wallon sobre a não separatividade entre homem e mundo.This paper focuses on the contributions from Henri Wallon about the relationship between cognition and affectivity in the education. It also defines the complex interdependency between affective and cognitive dimensions of such theory and emphasizes the notion of engaged person as a fundamental synthesis to understanding the relationship between affectivity and cognition in the educational field. This article also highlights the importance of dialectical and humanist view of integral person for educational practices and it incorporates the idea of "fundamental circularity" of Francisco Varela aiming to updating the view of Wallon about non-separateness between human beings and world.

  12. Single molecule force spectroscopy data and BD- and MD simulations on the blood protein von Willebrand factor

    Directory of Open Access Journals (Sweden)

    Sandra Posch

    2016-09-01

    Full Text Available We here give information for a deeper understanding of single molecule force spectroscopy (SMFS data through the example of the blood protein von Willebrand factor (VWF. It is also shown, how fitting of rupture forces versus loading rate profiles in the molecular dynamics (MD loading-rate range can be used to demonstrate the qualitative agreement between SMFS and MD simulations. The recently developed model by Bullerjahn, Sturm, and Kroy (BSK was used for this demonstration. Further, Brownian dynamics (BD simulations, which can be utilized to estimate the lifetimes of intramolecular VWF interactions under physiological shear, are described. For interpretation and discussion of the methods and data presented here, we would like to directly point the reader to the related research paper, “Mutual A domain interactions in the force sensing protein von Willebrand Factor” (Posch et al., 2016 [1]. Keywords: Atomic force microscopy, Single molecule force spectroscopy, Molecular dynamics simulation, Brownian dynamics simulation, von Willebrand factor

  13. Mixed-oxide (MOX) fuel performance benchmark. Summary of the results for the PRIMO MOX rod BD8

    International Nuclear Information System (INIS)

    Ott, L.J.; Sartori, E.; Costa, A.; ); Sobolev, V.; Lee, B-H.; Alekseev, P.N.; Shestopalov, A.A.; Mikityuk, K.O.; Fomichenko, P.A.; Shatrova, L.P.; Medvedev, A.V.; Bogatyr, S.M.; Khvostov, G.A.; Kuznetsov, V.I.; Stoenescu, R.; Chatwin, C.P.

    2009-01-01

    The OECD/NEA Nuclear Science Committee has established an Expert Group that deals with the status and trends of reactor physics, nuclear fuel performance, and fuel cycle issues related to the disposition of weapons-grade plutonium as MOX fuel. The activities of the NEA Expert Group on Reactor-based Plutonium Disposition are carried out in close cooperation with the NEA Working Party on Scientific Issues in Reactor Systems (WPRS). A major part of these activities includes benchmark studies. This report describes the results of the PRIMO rod BD8 benchmark exercise, the second benchmark by the TFRPD relative to MOX fuel behaviour. The corresponding PRIMO experimental data have been released, compiled and reviewed for the International Fuel Performance Experiments (IFPE) database. The observed ranges (as noted in the text) in the predicted thermal and FGR responses are reasonable given the variety and combination of thermal conductivity and FGR models employed by the benchmark participants with their respective fuel performance codes

  14. First intermediate break test 6IB1 data comparison with a TRAC-BD1/MOD1 blind calculation

    International Nuclear Information System (INIS)

    Wheatley, P.D.

    1985-04-01

    TRAC-BD1/MOD1 has been used to calculate the behavior in the FIST (Full Integral Test Facility) facility during an intermediate break in one of the recirculation loops. Results of the calculation are compared with the data from the experiment, and the analysis is discussed in this report. The calculation was blind with only the initial and boundary conditions available prior to performance of the calculation. The calculation has been previously documented without reference to the experimental data (i.e., prior to release of the data). This report extends the prior report by discussing the analysis of the data to code comparisons. This work was performed as part of the Nuclear Regulatory Commission's support to the FIST program which is being provided at the Idaho National Engineering Laboratory

  15. Premarket evaluations of the IMDx C. difficile for Abbott m2000 Assay and the BD Max Cdiff Assay.

    Science.gov (United States)

    Stellrecht, K A; Espino, A A; Maceira, V P; Nattanmai, S M; Butt, S A; Wroblewski, D; Hannett, G E; Musser, K A

    2014-05-01

    Clostridium difficile-associated diarrhea is a well-recognized complication of antibiotic use. Historically, diagnosing C. difficile has been difficult, as antigen assays are insensitive and culture-based methods require several days to yield results. Nucleic acid amplification tests (NAATs) are quickly becoming the standard of care. We compared the performance of two automated investigational/research use only (IUO/RUO) NAATs for the detection of C. difficile toxin genes, the IMDx C. difficile for Abbott m2000 Assay (IMDx) and the BD Max Cdiff Assay (Max). A prospective analysis of 111 stool specimens received in the laboratory for C. difficile testing by the laboratory's test of record (TOR), the BD GeneOhm Cdiff Assay, and a retrospective analysis of 88 specimens previously determined to be positive for C. difficile were included in the study. One prospective specimen was excluded due to loss to follow-up discrepancy analysis. Of the remaining 198 specimens, 90 were positive by all three methods, 9 were positive by TOR and Max, and 3 were positive by TOR only. One negative specimen was initially inhibitory by Max. The remaining 95 specimens were negative by all methods. Toxigenic C. difficile culture was performed on the 12 discrepant samples. True C. difficile-positive status was defined as either positive by all three amplification assays or positive by toxigenic culture. Based on this definition, the sensitivity and specificity were 96.9% and 95% for Max and 92.8% and 100% for IMDx. In summary, both highly automated systems demonstrated excellent performance, and each has individual benefits, which will ensure that they will both have a niche in clinical laboratories.

  16. The Paradox of Being a Wounded Healer: Henri J.M. Nouwen’s Contribution to Pastoral Theology

    Directory of Open Access Journals (Sweden)

    S. Philip Nolte

    2010-11-01

    Full Text Available This article is the first in a series of two dealing with Henri Nouwen’s contribution to pastoral care. The present article focuses on the impact of cognitive dissonance and the role it plays in pastors becoming constrained in their ministry. The point of departure is that during the past two decades, pastors have been subjected to profound changes. While pastors view their involvement with people in the social and faith communities in which they live and work as guiding people towards a life of wholeness and integrity, they themselves, because of their own inner woundedness, struggle to live a life of wholeness. This article investigates how pastors can act congruently and with integrity in a world that has been profoundly changed by a shift from a modern to a postmodern paradigm. This reflection explores the ancient Greek mythological origins of the concept ‘wounded healer’. It also shows that, in its utilisation by the Swiss psychiatrist Carl Jung, the concept became a metaphor. This insight leads to a discussion of how Henri Nouwen applied the significance of the metaphor to pastoral ministry. The discussion takes on the form of certain relevant biographical side notes on Nouwen’s contribution to pastoral theology. The article concludes with an exposition of Nouwens’s use of the metaphor in his book, The wounded healer: Ministry in contemporary society.

  17. Henri Lopès : d’Une Quête Incessante à une identité plurielle

    Directory of Open Access Journals (Sweden)

    Vincent Simédoh

    2006-04-01

    Full Text Available Dans plusieurs oeuvres d’Henri Lopès, les personnages sont constamment en quête d’une identité. Une quête qu’ils entament comme un parcours puisque désormais ils vivent au confluent de plusieurs cultures et ils se sentent comme en exil. Ce n’est pas forcément un exil extérieur parce qu’ils ont quitté leur pays d’origine mais c’est plutôt un exil intérieur. Ainsi les personnages se sentent incapables de se situer par rapport à eux-mêmes et à autrui. Dès lors surgit une tentation, celle de se réfugier dans le souvenir qui n’existe même plus. La mémoire s’estompe. L’histoire elle-même fuit et disparaît. Ce qui fait naître chez les personnages un vide qui conduit à un malaise identitaire, d’où déchirement. En face de cet écartèlement, surgit une multitude de pistes. Et c’est dans cette perspective qu’Henri Lopès propose une identité plurielle.

  18. «Ancient armour and arms recently received from Spain» Eusebio Zuloaga, Henry Lepage, and the Real Armería in Madrid

    Directory of Open Access Journals (Sweden)

    Pyhrr, Stuart W.

    1999-12-01

    Full Text Available In 1835 an important group of arms, some of them from Real Armeria, was sent by Eusebio Zuloaga to the gunmaker Henri Lepage in Paris. This paper documents the transaction and seeks to identify the present location of some items.

    En 1835 un importante conjunto de armas, algunas procedentes de la Real Armeria, fue enviado por Eusebio Zuloaga a1 arcabucero Henri Lepage de París. Este artículo documenta dicho envió y pretende señalar el paradero actual de alguno de los objetos

  19. Comparison of the identification results of Candida species obtained by BD Phoenix™ and Maldi-TOF (Bruker Microflex LT Biotyper 3.1).

    Science.gov (United States)

    Marucco, Andrea P; Minervini, Patricia; Snitman, Gabriela V; Sorge, Adriana; Guelfand, Liliana I; Moral, Laura López

    2018-02-05

    In patients with invasive fungal infections, the accurate and rapid identification of the genus Candida is of utmost importance since antimycotic sensitivity is closely related to the species. The aim of the present study was to compare the identification results of species of the genus Candida obtained by BD Phoenix™ (Becton Dickinson [BD]) and Maldi-TOF MS (Bruker Microflex LT Biotyper 3.1). A total of 192 isolates from the strain collection belonging to the Mycology Network of the Autonomous City of Buenos Aires, Argentina, were analyzed. The observed concordance was 95%. Only 10 strains (5%) were not correctly identified by the BD Phoenix™ system. The average identification time with the Yeast ID panels was 8h 22min. The BD Phoenix™ system proved to be a simple, reliable and effective method for identifying the main species of the genus Candida. Copyright © 2017 Asociación Argentina de Microbiología. Publicado por Elsevier España, S.L.U. All rights reserved.

  20. 13 CFR 124.502 - How does an agency offer a procurement to SBA for award through the 8(a) BD program?

    Science.gov (United States)

    2010-01-01

    ... history, if any, of the requirement; (10) The names and addresses of any small business contractors which... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false How does an agency offer a procurement to SBA for award through the 8(a) BD program? 124.502 Section 124.502 Business Credit and...

  1. Glycoprotein from street rabies virus BD06 induces early and robust immune responses when expressed from a non-replicative adenovirus recombinant.

    Science.gov (United States)

    Wang, Shuchao; Sun, Chenglong; Zhang, Shoufeng; Zhang, Xiaozhuo; Liu, Ye; Wang, Ying; Zhang, Fei; Wu, Xianfu; Hu, Rongliang

    2015-09-01

    The rabies virus (RABV) glycoprotein (G) is responsible for inducing neutralizing antibodies against rabies virus. Development of recombinant vaccines using the G genes from attenuated strains rather than street viruses is a regular practice. In contrast to this scenario, we generated three human adenovirus type 5 recombinants using the G genes from the vaccine strains SRV9 and Flury-LEP, and the street RABV strain BD06 (nrAd5-SRV9-G, nrAd5-Flury-LEP-G, and nrAd5-BD06-G). These recombinants were non-replicative, but could grow up to ~10(8) TCID50/ml in helper HEK293AD cells. Expression of the G protein was verified by immunostaining, quantitative PCR and cytometry. Animal experiments revealed that immunization with nrAd5-BD06-G can induce a higher seroconversion rate, a higher neutralizing antibody level, and a longer survival time after rabies virus challenge in mice when compared with the other two recombinants. Moreover, the expression of granulocyte-macrophage colony-stimulating factor (GM-CSF) was significantly higher in mice immunized with nrAd5-BD06-G, which might also contribute to the increased protection. These results show that the use of street RABV G for non-replicative systems may be an alternative for developing effective recombinant rabies vaccines.

  2. The Drosophila Gr28bD product is a non-specific cation channel that can be used as a novel thermogenetic tool.

    Science.gov (United States)

    Mishra, Aditi; Salari, Autoosa; Berigan, Benton R; Miguel, Kayla C; Amirshenava, Marzie; Robinson, Abbey; Zars, Benjamin C; Lin, Jenna L; Milescu, Lorin S; Milescu, Mirela; Zars, Troy

    2018-01-17

    Extrinsic control of single neurons and neuronal populations is a powerful approach for understanding how neural circuits function. Adding new thermogenetic tools to existing optogenetic and other forms of intervention will increase the complexity of questions that can be addressed. A good candidate for developing new thermogenetic tools is the Drosophila gustatory receptor family, which has been implicated in high-temperature avoidance behavior. We examined the five members of the Gr28b gene cluster for temperature-dependent properties via three approaches: biophysical characterization in Xenopus oocytes, functional calcium imaging in Drosophila motor neurons, and behavioral assays in adult Drosophila. Our results show that Gr28bD expression in Xenopus oocytes produces a non-specific cationic current that is activated by elevated temperatures. This current is non-inactivating and non-voltage dependent. When expressed in Drosophila motor neurons, Gr28bD can be used to change the firing pattern of individual cells in a temperature-dependent fashion. Finally, we show that pan-neuronal or motor neuron expression of Gr28bD can be used to alter fruit fly behavior with elevated temperatures. Together, these results validate the potential of the Gr28bD gene as a founding member of a new class of thermogenetic tools.

  3. Isolation and characterization of two new lipopeptide biosurfactants produced by Pseudomonas fluorescens BD5 isolated from water from the Arctic Archipelago of Svalbard

    Czech Academy of Sciences Publication Activity Database

    Janek, T.; Lukaszewicz, M.; Řezanka, Tomáš; Krasowska, A.

    2010-01-01

    Roč. 101, č. 15 (2010), s. 6118-6123 ISSN 0960-8524 Institutional research plan: CEZ:AV0Z50200510 Keywords : Pseudomonas fluorescens BD5 * Lipopeptide * Pseudofactins Subject RIV: EE - Microbiology, Virology Impact factor: 4.365, year: 2010

  4. Let us keep observing and play in sand boxes (Henry Darcy Medal Lecture)

    Science.gov (United States)

    Illangasekare, T. H.

    2012-04-01

    Henry Darcy was a civil engineer recognized for a number of technical achievements and scientific discoveries. The sand column experiments for which he is known revealed the linear relationship that exists between fluid motion and driving forces at low velocities. Freeze and Back (1983) stated, ''The experiments carried out by Darcy with the help of his assistant, Ritter, in Dijon, France in 1855 and 1856 represent the beginning of groundwater hydrology as a quantitative science." Because of the prominence given to this experiment, two important facts behind Darcy's contributions to subsurface hydrology have not received much attention. First, Darcy was not only a good engineer, but he was also a highly respected scientist whose knowledge of both the fundamentals of fluid mechanics and the natural world of geology led to better conceptualizing and quantifying of groundwater processes at relevant scales to solve practical problems. The experiments for which he is known may have already been conceived, based on his theoretical understanding, and the results were anticipated (Brown 2002). Second, Darcy, through his contributions with Dupuit, showed that they understood hydrologeology at a regional scale and developed methods for quantification at the scale of geologic stratum (Ritz and Bobek, 2008). The primary thesis of this talk is that scientific contributions such as the one Darcy made require appreciation and a thorough understanding of fundamental theory coupled with observation and recording of phenomena both in nature and in the laboratory. Along with all of the significant theoretical, mathematical modeling, and computational advances we have made in the last several decades, laboratory experiments designed to observe phenomena and processes for better insight, accurate data generation, and hypothesis development are critically important to make scientific and engineering advances to address some of the emerging and societally important problems in hydrology

  5. Henry Hub and national balancing point prices: what will be the international gas price reference?

    International Nuclear Information System (INIS)

    Mazighi, A.E.H.

    2005-01-01

    One of the lessons in the history of international trade in commodities is the emergence - sooner or later - of an international price reference, most commonly known as an international marker price. In the area of oil, West Texas Intermediate (WTI) plays the role of a marker for sour crudes traded in the Atlantic basin. Brent oil fulfils this function for sweet crudes traded in Europe. Another important aspect in the area of global commodities is that the emergence of a marker price is not always necessarily related to the relative share of production of exports of the commodity, but primarily to the existence of an organized market for this commodity. Today, while international gas trade is intensifying, we still lack an international price reference for this commodity. This is due to the fact that the international trade of natural gas is still highly regionalized. It is also due to the fact that most gas markets are still regulated. Nevertheless, deregulation efforts have been implemented in both developed (the United States, the United Kingdom, continental Europe, Korea) and developing countries (Brazil, Chile) and have led to new market structures based on more competition in all segments of the gas chain, except transportation. In the meantime, price structures based on supply and demand principles are supposed to have emerged in the US and UK markets in the 1990s as a result of the implementation of deregulation measures. Today, the US gas market, which represents more than 660 billion cubic metres per year of consumption and the UK gas market, which is close to 100 bcm annually, are considered mature enough to make the principles of supply and demand operate inside these markets. In fact, the Henry Hub (HH) price, which is determined at a physical location in Louisiana, US, and the national balancing point (NBP) price, which is determined somewhere inside the national transmission system (NTS), without any precise location, are considered as potential

  6. A dual mechanism involved in membrane and nucleic acid disruption of AvBD103b, a new avian defensin from the king penguin, against Salmonella enteritidis CVCC3377.

    Science.gov (United States)

    Teng, Da; Wang, Xiumin; Xi, Di; Mao, Ruoyu; Zhang, Yong; Guan, Qingfeng; Zhang, Jun; Wang, Jianhua

    2014-10-01

    The food-borne bacterial gastrointestinal infection is a serious public health threat. Defensins are evolutionarily conserved innate immune components with broad-spectrum antibacterial activity that do not easily induce resistance. AvBD103b, an avian defensin with potent activity against Salmonella enteritidis, was isolated from the stomach contents of the king penguin (Aptenodytes patagonicus). To elucidate further the antibacterial mechanism of AvBD103b, its effect on the S. enteritidis CVCC3377 cell membrane and intracellular DNA was researched. The cell surface hydrophobicity and a N-phenyl-1-naphthylamine uptake assay demonstrated that AvBD103b treatment increased the cell surface hydrophobicity and outer membrane permeability. Atomic absorption spectrometry, ultraviolet spectrophotometry, flow cytometry, and transmission electron microscopy (TEM) indicated that AvBD103b treatment can lead to the release of the cellular contents and cell death through damage of the membrane. DNA gel retardation and circular dichroism analysis demonstrated that AvBD103b interacted with DNA and intercalated into the DNA base pairs. A cell cycle assay demonstrated that AvBD103b affected cellular functions, such as DNA synthesis. Our results confirmed that AvBD103b exerts its antibacterial activity by damaging the cell membrane and interfering with intracellular DNA, ultimately causing cell death, and suggested that AvBD103b may be a promising candidate as an alternative to antibiotics against S. enteritidis.

  7. 驯鹿β-防御素-1(reBD-1)基因在组织中表达的原位杂交检测%Detection of reindeer β-defensin-1 (reBD-1) gene's expression in tissues by in situ hybridization

    Institute of Scientific and Technical Information of China (English)

    杨银凤; 赵艳芳; 都格尔斯仁; 吴萨日娜

    2007-01-01

    β-防御素主要是由哺乳动物黏膜上皮细胞产生,分布在机体宿主-环境的界面位置.在本研究中,利用已克隆的驯鹿β-防御素reBD-1 cDNA作为探针,经地高辛标记后再应用原位杂交技术检测reBD-1 mRNA在驯鹿组织内的表达部位.结果显示reBD-1 mRNA表达在舌背表面的复层扁平上皮内,实质性器官肾也表达在肾小管及肾小囊上皮内,而淋巴器官脾脏内reBD-1 mRNA表达在淋巴细胞和红髓的巨噬细胞内.表明驯鹿β-防御素不仅表达在上皮细胞内,而且在非上皮细胞内也有表达,提示reBD-1在黏膜和系统防御中均起着重要的作用.

  8. On the "Critique of Everyday Life" to "Metaphilosophy": Henri Lefebvre's Philosophical-Political Legacy of the Cultural Revolution

    Science.gov (United States)

    Sünker, Heinz

    2014-01-01

    Henri Lefebvre (1901-91), philosopher and sociologist, is, together with Theodor W. Adorno, Max Horkheimer, Walter Benjamin and Ernst Bloch, one of the most relevant representatives of the first generation in Western Marxism. His engagement with Marxism led him to analyse everyday life in post-war France in order to decipher the possibilities of,…

  9. A Guide to the Data Resources of the Henry A. Murray Research Center of Radcliffe College: A Center for the Study of Lives [and] Index to [the] Guide.

    Science.gov (United States)

    Radcliffe Coll., Cambridge, MA. Henry A. Murray Research Center.

    The first of two volumes provides information about data resources available at the Henry A. Murray Research Center of Radcliffe College, a multidisciplinary research center that is a national repository for social and behavioral science data on human development and social change; topics of special concern to women are collection priorities. The…

  10. Henry S. Turner, The English Renaissance Stage. Geometry, Poetics, and the Practical Spatial Arts 1580-1630 - Tim Fitzpatrick, Playwright, Space and Place in Early Modern Performance

    Directory of Open Access Journals (Sweden)

    Luigi Giuliani

    2013-05-01

    Full Text Available Review of Henry S. Turner, The English Renaissance Stage. Geometry, Poetics, and the Practical Spatial Arts 1580-1630, Oxford University Press, Oxford, 2006, reimpr. 2010, 326 pp. ISBN: 978-0-19-959545-7 y Tim Fitzpatrick, Playwright, Space and Place in Early Modern Performance, Ashgate, Franham, 2011, 314 pp. ISBN: 978-1-4094-2827-5.

  11. From the "metaphysics of the individual" to the critique of society: on the practical significance of Michel Henry's phenomenology of life.

    Science.gov (United States)

    Staudigl, Michael

    This essay explores the practical significance of Michel Henry's "material phenomenology." Commencing with an exposition of his most basic philosophical intuition, i.e., his insight that transcendental affectivity is the primordial mode of revelation of our selfhood, the essay then brings to light how this intuition also establishes our relation to both the world and others. Animated by a radical form of the phenomenological reduction, Henry's material phenomenology brackets the exterior world in a bid to reach the concrete interior transcendental experience at the base of all exteriority. The essay argues that this "counter reduction," designed as a practical orientation to the world, suspends all traditional parameters of onto(theo)logical individuation in order to rethink subjectivity in terms of its transcendental corporeality, i.e., in terms of the invisible display of "affective flesh." The development of this "metaphysics of the individual" anchors his "practical philosophy" as he developed it-under shifting accents-throughout his oeuvre. In particular, the essay brings into focus Henry's reflections on modernity, the industry of mass culture and their "barbaric" movements. The essay briefly puts these cultural and political areas of Henry's of thinking into contact with his late "theological turn," i.e., his Christological account of Life and the (inter)subjective self-realization to which it gives rise.

  12. [The electric furnace of Henri Moissan at one hundred years: connection with the electric furnace, the solar furnace, the plasma furnace?].

    Science.gov (United States)

    Royère, C

    1999-03-01

    The trace of Henri Moissan's pioneer work 100 years ago is clearly evidenced by an overview of achievements in high temperature devices; 1987: "Le four électrique" by Henri Moissan; 1948-1952: "High temperature heating in a cavity rotary kiln using focusing of solar radiation" by Félix Trombe; 1962: "The cavity rotary kiln using focused solar radiation jointly with a plasma gun" by Marc Foëx; 1970: "The rotary kiln with two plasma guns and arc transfer" by Marc Foëx; 1984: "The plasma furnace" by Electricité de France (EDF) at Renardières; 1997: "The plasma furnace" by the Atomic Energy Center (CEA) at Cadarache, the VULCANO program. The first part of this contribution is devoted to Henri Moissan. Re-reading his early book on the electric furnace, especially the first chapter and the sections on silica, carbon vapor and experiments performed in casting molten metal--the conclusions are outstanding--provides modern readers with an amazing insight into future developments. The last two parts are devoted to Félix Trombe and Marc Foëx, tracing the evolution of high temperature cavity processus leading to the solar furnace and the present day plasma furnace at the CEA. Focus is placed on research conducted by the French National Center for Scientific Research (CNRS) with the solar and plasma furnaces at Odeillo. The relationships with Henri Moissan's early work are amazing, offering a well deserved homage to this pioneer researcher.

  13. Le cavalier du Pont-Neuf : histoire, restauration et secrets de la statue équestre de Henri IV

    Directory of Open Access Journals (Sweden)

    Pascal Liévaux

    2012-04-01

    Full Text Available Figure 1État des surfaces de la statue après la restaurationPhot. C. Usaï, 2004Henri IV, roi aimé des français entre tous, est cette année célébré à l’occasion du quatrième centenaire de son assassinat. Aussi la revue In Situ a-t-elle souhaité marquer l’anniversaire de cet événement majeur de l’histoire de France en mettant à la disposition du public les résultats inédits de travaux réalisés à l’occasion de la restauration du monument le plus emblématique du mémorial henricien : la statue équ...

  14. Henri Cartier-Bresson / Walker Evans : Photographier l’Amérique (1929-1947

    Directory of Open Access Journals (Sweden)

    François Brunet

    2009-08-01

    Full Text Available Dans un mot adressé en 2001 à Peter Galassi, conservateur de la photographie au MOMA, Henri Cartier-Bresson, alors âgé de quatre-vingt-treize ans, écrivait plaisamment — mais non pas complaisamment : « If it had not been for the challenge of the work of Walker Evans, I don’t think I would have remained a fotographer » (« sans le défi constitué par le travail de Walker Evans, je ne crois pas que je serais resté fotographe ». Pour fêter le centenaire de Cartier-Bresson, c’est ce défi — plutôt ...

  15. William Henry Bragg, man and scientist, Nobel Laureate and First Professor of Physics, University of Adelaide 1886-1909.

    Science.gov (United States)

    Patterson, John; George, Robert

    2018-03-01

    In London, November 1915, a telegram was received at the home of William Henry Bragg from the secretary of the Academy of Science in Stockholm announcing the award of the Nobel Prize in Physics for "the analysis of crystal structures by means of X-rays". A second similar telegram was addressed to his 25 year old son William Lawrence Bragg (Jenkin, 2008). This article commemorates the centenary of that event and the unveiling of a bust of Sir William Bragg alongside that of his son, Sir Lawrence Bragg, on North Terrace in Adelaide where he spent 23 years of his early career. Copyright © 2018. Published by Elsevier Ltd.

  16. Dreamers in dialogue: evolution, sex and gender in the utopian visions of William Morris and William Henry Hudson

    Directory of Open Access Journals (Sweden)

    Caterina Novák

    2013-12-01

    Full Text Available The aim of this article is to explore the parallels between two late-nineteenth-century utopias,William Henry Hudsons A Crystal Age (1882 and William Morriss News from Nowhere (1891. Itaims to explore how these two works respond to the transition from a kinetic to a static conception ofutopia that under pressure from evolutionary and feminist discourses took place during the period.Particular focus lies on the way in which this is negotiated through the depiction of evolution, sexuality,and gender roles in the respective novels, and how the depiction of these disruptive elements may workas a means of ensuring the readers active engagement in political, intellectual and emotional terms.

  17. Promoting good health in the age of reform: the medical publications of Henry H. Porter of Philadelphia, 1829-32.

    Science.gov (United States)

    Horrocks, T A

    1995-01-01

    In the early 1830s, the Philadelphia publisher Henry H. Porter rapidly published five journals, six books, and an almanac, works having a particular emphasis on health and personal hygiene. Porter's health publications linked the traditional message about the importance of personal hygiene to health to the messages conveyed by the flourishing American reform movements at the time, and his Journal of Health was among the first American medically oriented periodicals published for the layperson. Yet Porter did not survive in the intensely competitive and financially unstable book trade. This study examines Porter's health publications, attempting to explain why he chose to publish what he did, the message(s) his works contained, the audience(s) he tried to reach, and the failure of his business.

  18. Of benches and Wenches : Subversion de l’espace et topologie de la tyrannie dans I Henry IV

    OpenAIRE

    Lecercle, Ann

    2018-01-01

    Comme l’on sait, le système spatial dominant au Moyen Age et pendant la Renaissance est un système d’isomorphismes à échelle mais non à géométrie variable, que nous connaissons sous les termes de “macrocosme et microcosme”. Dans le contexte de Henry IV, il faut infléchir ce paradigme en fonction de la conception élisabéthaine de l’espace spécifiquement national. Cette conception est exposée, à l’échelle européenne, par Perry Anderson dans son livre Lineages of the Absolutist State : évoquant ...

  19. Henry Currey FRIBA (1820-1900): leading Victorian hospital architect, and early exponent of the "pavilion principle".

    Science.gov (United States)

    Cook, G C

    2002-06-01

    The "pavilion plan" for hospital design originated in France in the 18th century and was popularised in England by John Roberton and George Godwin in the mid-19th century; the underlying rationale was that with improved ventilation the mortality rate (at that time exceedingly high) was significantly reduced. Among the enthusiasts for this new style was Florence Nightingale (herself a miasmatist)--who had experienced astronomically high death rates in the hospital at Scutari during the Crimean War (1854-6). One of the leading exponents of this style of hospital architecture was Henry Currey (1820-1900) whose greatest achievement was undoubtedly the design for the new St Thomas's Hospital on the Lambeth Palace Road.

  20. Polyphony and counterpoint: Mechanisms of seduction in the diaries of Helen Hessel and Henri Pierre Roché

    Directory of Open Access Journals (Sweden)

    Catherine du Toit

    2015-06-01

    Polifonie en kontrapunt: Meganismes van verleiding in die dagboeke van Helen Hessel en Henri Pierre Roché. Henri Pierre Roché (1879–1959, outeur van Jules et Jim, word beskryf as ‘n sosiale koppelaar, ‘n model-liefhebber van alles en nog wat, ‘n versamelaar van vroue en kuns en een van die mees produktiewe dagboekskrywers en aktiewe minnaars in die opgetekende geskiedenis. Roché het ‘n reeks sketse oor Don Juan gepubliseer en was geboei deur die figuur van die verleier. In sy twintigs beplan hy om sy lewe te wy aan die skepping van ‘n œuvre wat die morele, intellektuele, sosiale en seksuele verhoudings tussen mans en vrouens sou ondersoek. Ter bereiking van hierdie doel, rig hy sy lewe in as laboratorium waarin werklike ondervindinge dien as hoofbron van inligting. Sy dagboek strek oor sestig jaar en is ryk aan verhale van verleiding. Desnieteenstaande bly die mees intense en boeiende intrige van verleiding en verraad steeds sy verhouding met Helen Hessel. Aan die begin van hulle verhouding, stel Roché voor dat sy ook ‘n dagboek hou van hulle hartstogtelike liefde. Helen Hessel se dagboek, geskryf in Frans, Duits en Engels, reflekteer die drama van verleiding en funksioneer op verskillende vlakke: realisties, visionêr, ten volle geabsorbeer in haar eie gedagtes en emosies en tóg krities jeens haarself en ander. ‘n Vergelyking van die twee dagboeke skep ‘n fassinerende, digte tekstuur wat die binnewerkings blootlê van verleiding in aksie. Die kontrapunt geskep deur hierdie twee interafhanklike stemme word nóg meer kompleks namate ‘n mens bewus word van die intertekstuele verwysings wat bydra tot die ontluikende polifonie van geskrewe liefde en lewe.

  1. Gausbert de Poicibot, “Be·s cuget venjar Amors” (BdT 173.2

    Directory of Open Access Journals (Sweden)

    Francesca Andolfato

    2010-09-01

    Full Text Available This paper offers a commentary and a new critical edition of Gausbert de Poicibot’s poem “Be·s cuget venjar Amors”, which apparently belongs to the genre of the ‘mala chanso’, that was particularly popular during the period that the Limousin poet was active. To abandon love enables the poet to recuperate reason and ‘sen’ and to justify, almost in didactic terms, his separation from the lady, thus clearly showing that he had so far sung the praises of a lady who was not worthy of receiving them. The song is also compared to other typical examples of the subgenre to which it belongs, such as “Si be·m partetz, mala dompna, de vos” by Gui d’Uissel (BdT 194.19, considered to be paradigmatic of the ‘mala chanso’ and probably familiar to Gausbert de Poicibot, though it will be pointed out that this poetic mode has roots in the work of troubadours of previous generations, such as Bernart de Ventadorn and Raimbaut d’Aurenga, whom Gausbert seems to use as models.

  2. TRUMP-BD: A computer code for the analysis of nuclear fuel assemblies under severe accident conditions

    International Nuclear Information System (INIS)

    Lombardo, N.J.; Marseille, T.J.; White, M.D.; Lowery, P.S.

    1990-06-01

    TRUMP-BD (Boil Down) is an extension of the TRUMP (Edwards 1972) computer program for the analysis of nuclear fuel assemblies under severe accident conditions. This extension allows prediction of the heat transfer rates, metal-water oxidation rates, fission product release rates, steam generation and consumption rates, and temperature distributions for nuclear fuel assemblies under core uncovery conditions. The heat transfer processes include conduction in solid structures, convection across fluid-solid boundaries, and radiation between interacting surfaces. Metal-water reaction kinetics are modeled with empirical relationships to predict the oxidation rates of steam-exposed Zircaloy and uranium metal. The metal-water oxidation models are parabolic in form with an Arrhenius temperature dependence. Uranium oxidation begins when fuel cladding failure occurs; Zircaloy oxidation occurs continuously at temperatures above 13000 degree F when metal and steam are available. From the metal-water reactions, the hydrogen generation rate, total hydrogen release, and temporal and spatial distribution of oxide formations are computed. Consumption of steam from the oxidation reactions and the effect of hydrogen on the coolant properties is modeled for independent coolant flow channels. Fission product release from exposed uranium metal Zircaloy-clad fuel is modeled using empirical time and temperature relationships that consider the release to be subject to oxidation and volitization/diffusion (''bake-out'') release mechanisms. Release of the volatile species of iodine (I), tellurium (Te), cesium (Ce), ruthenium (Ru), strontium (Sr), zirconium (Zr), cerium (Cr), and barium (Ba) from uranium metal fuel may be modeled

  3. Rcupcake: an R package for querying and analyzing biomedical data through the BD2K PIC-SURE RESTful API.

    Science.gov (United States)

    Gutiérrez-Sacristán, Alba; Guedj, Romain; Korodi, Gabor; Stedman, Jason; Furlong, Laura I; Patel, Chirag J; Kohane, Isaac S; Avillach, Paul

    2018-04-15

    In the era of big data and precision medicine, the number of databases containing clinical, environmental, self-reported and biochemical variables is increasing exponentially. Enabling the experts to focus on their research questions rather than on computational data management, access and analysis is one of the most significant challenges nowadays. We present Rcupcake, an R package that contains a variety of functions for leveraging different databases through the BD2K PIC-SURE RESTful API and facilitating its query, analysis and interpretation. The package offers a variety of analysis and visualization tools, including the study of the phenotype co-occurrence and prevalence, according to multiple layers of data, such as phenome, exposome or genome. The package is implemented in R and is available under Mozilla v2 license from GitHub (https://github.com/hms-dbmi/Rcupcake). Two reproducible case studies are also available (https://github.com/hms-dbmi/Rcupcake-case-studies/blob/master/SSCcaseStudy_v01.ipynb, https://github.com/hms-dbmi/Rcupcake-case-studies/blob/master/NHANEScaseStudy_v01.ipynb). paul_avillach@hms.harvard.edu. Supplementary data are available at Bioinformatics online.

  4. Use of an automated blood culture system (BD BACTEC™) for diagnosis of prosthetic joint infections: easy and fast.

    Science.gov (United States)

    Minassian, Angela M; Newnham, Robert; Kalimeris, Elizabeth; Bejon, Philip; Atkins, Bridget L; Bowler, Ian C J W

    2014-05-04

    For the diagnosis of prosthetic joint infection (PJI) automated BACTEC™ blood culture bottle methods have comparable sensitivity, specificity and a shorter time to positivity than traditional cooked meat enrichment broth methods. We evaluate the culture incubation period required to maximise sensitivity and specificity of microbiological diagnosis, and the ability of BACTEC™ to detect slow growing Propionibacteria spp. Multiple periprosthetic tissue samples taken by a standardised method from 332 patients undergoing prosthetic joint revision arthroplasty were cultured for 14 days, using a BD BACTEC™ instrumented blood culture system, in a prospective study from 1st January to 31st August 2012. The "gold standard" definition for PJI was the presence of at least one histological criterion, the presence of a sinus tract or purulence around the device. Cases where > =2 samples yielded indistinguishable isolates were considered culture-positive. 1000 BACTEC™ bottle cultures which were negative after 14 days incubation were sub-cultured for Propionibacteria spp. 79 patients fulfilled the definition for PJI, and 66 of these were culture-positive. All but 1 of these 66 culture-positive cases of PJI were detected within 3 days of incubation. Only one additional (clinically-insignificant) Propionibacterium spp. was identified on terminal subculture of 1000 bottles. Prolonged microbiological culture for 2 weeks is unnecessary when using BACTEC™ culture methods. The majority of clinically significant organisms grow within 3 days, and Propionibacteria spp. are identified without the need for terminal subculture. These findings should facilitate earlier decisions on final antimicrobial prescribing.

  5. SUBSTELLAR-MASS COMPANIONS TO THE K-GIANTS HD 240237, BD +48 738, AND HD 96127

    International Nuclear Information System (INIS)

    Gettel, S.; Wolszczan, A.; Niedzielski, A.; Nowak, G.; Adamów, M.; Zieliński, P.; Maciejewski, G.

    2012-01-01

    We present the discovery of substellar-mass companions to three giant stars by the ongoing Penn State-Toruń Planet Search conducted with the 9.2 m Hobby-Eberly Telescope. The most massive of the three stars, K2-giant HD 240237, has a 5.3 M J minimum mass companion orbiting the star at a 746 day period. The K0-giant BD +48 738 is orbited by a ≥0.91 M J planet which has a period of 393 days and shows a nonlinear, long-term radial velocity (RV) trend that indicates a presence of another, more distant companion, which may have a substellar mass or be a low-mass star. The K2-giant HD 96127 has a ≥4.0 M J mass companion in a 647 day orbit around the star. The two K2-giants exhibit a significant RV noise that complicates the detection of low-amplitude, periodic variations in the data. If the noise component of the observed RV variations is due to solar-type oscillations, we show, using all the published data for the substellar companions to giants, that its amplitude is anti-correlated with stellar metallicity.

  6. Detecting asymptomatic Trichomonas vaginalis in females using the BD ProbeTec™ Trichomonas vaginalis Qx nucleic acid amplification test.

    Science.gov (United States)

    Lord, Emily; Newnham, Tana; Dorrell, Lucy; Jesuthasan, Gerald; Clarke, Lorraine; Jeffery, Katie; Sherrard, Jackie

    2017-03-01

    Trichomonas vaginalis (TV) rates in women are increasing and many are asymptomatic. Nucleic acid amplification tests (NAATs) are becoming the 'gold standard' for diagnosis. We aimed to establish our asymptomatic TV rates by testing all women attending Oxfordshire's Sexual Health service, regardless of symptoms, using the BD ProbeTec™ TV Q x NAATs (BDQ x ). During BDQ x 's verification process, the sensitivity and specificity were calculated using results of 220 endocervical samples from symptomatic women, compared with culture. BDQ x was subsequently implemented and prospectively evaluated over 6 months in female attendees. Wet mount microscopy was also performed in symptomatics. Demographic and clinical characteristics of those diagnosed were analysed. From 220 samples tested by BDQ x and culture: 5 were positive on both and one solely using BDQ x , giving a sensitivity and specificity of 100% and 99.53%, respectively. In the prospective cohort, of 5775 BDQ x tests, 33 (0.57%) were positive. 11/33 (33%) patients were asymptomatic. All patients diagnosed had risk factors: age >25 years (85%), residence in a deprived area (79%) and black ethnicity (21%). Despite BDQ x being highly sensitive and specific, with our low TV prevalence universal screening may not be justified. Targeted screening using local demographic data merits further investigation.

  7. TRUMP-BD: A computer code for the analysis of nuclear fuel assemblies under severe accident conditions

    Energy Technology Data Exchange (ETDEWEB)

    Lombardo, N.J.; Marseille, T.J.; White, M.D.; Lowery, P.S.

    1990-06-01

    TRUMP-BD (Boil Down) is an extension of the TRUMP (Edwards 1972) computer program for the analysis of nuclear fuel assemblies under severe accident conditions. This extension allows prediction of the heat transfer rates, metal-water oxidation rates, fission product release rates, steam generation and consumption rates, and temperature distributions for nuclear fuel assemblies under core uncovery conditions. The heat transfer processes include conduction in solid structures, convection across fluid-solid boundaries, and radiation between interacting surfaces. Metal-water reaction kinetics are modeled with empirical relationships to predict the oxidation rates of steam-exposed Zircaloy and uranium metal. The metal-water oxidation models are parabolic in form with an Arrhenius temperature dependence. Uranium oxidation begins when fuel cladding failure occurs; Zircaloy oxidation occurs continuously at temperatures above 13000{degree}F when metal and steam are available. From the metal-water reactions, the hydrogen generation rate, total hydrogen release, and temporal and spatial distribution of oxide formations are computed. Consumption of steam from the oxidation reactions and the effect of hydrogen on the coolant properties is modeled for independent coolant flow channels. Fission product release from exposed uranium metal Zircaloy-clad fuel is modeled using empirical time and temperature relationships that consider the release to be subject to oxidation and volitization/diffusion ( bake-out'') release mechanisms. Release of the volatile species of iodine (I), tellurium (Te), cesium (Ce), ruthenium (Ru), strontium (Sr), zirconium (Zr), cerium (Cr), and barium (Ba) from uranium metal fuel may be modeled.

  8. 驯鹿β-防御素-1(reBD-1)mRNA在驯鹿组织器官中的表达检测%The examination of expression of Reindeer β - defensin reBD - 1 mRNA in the tissues

    Institute of Scientific and Technical Information of China (English)

    吴萨日娜; 赵艳芳; 余兴帮; 都格尔斯仁; 杨银凤

    2006-01-01

    为了检测reBD-1 mRNA在驯鹿体内可能的表达器官,研究根据已知的reBD-1 cDNA序列设计了一对预计扩增产物为121 bp的引物,以驯鹿舌、食管、瘤胃、网胃、皱胃、十二指肠、回肠、结肠、肝、肺、气管、肾、膀胱、睾丸、附睾、心脏、脾脏中提取的总RNA为模板,采用反转录PCR(RT-PCR)技术检测驯鹿的上述器官内reBD-1 mRNA的表达情况.结果显示:reBD-1 mRNA在上述组织器官中均有表达,其中在舌、瘤胃、睾丸中表达最强;在食管、十二指肠、结肠、气管、脾脏中有中等量的表达;在网胃、皱胃、回肠、肝、肺、肾、膀胱、附睾、心脏内的表达较弱.β-防御素reBD-1在驯鹿体内的广泛表达提示reBD-1有助于驯鹿的先天性宿主防御.

  9. Efficacy of shared decision-making on treatment adherence of patients with bipolar disorder: a cluster randomized trial (ShareD-BD).

    Science.gov (United States)

    Samalin, L; Honciuc, M; Boyer, L; de Chazeron, I; Blanc, O; Abbar, M; Llorca, P M

    2018-04-13

    Shared decision-making (SDM) is a model of interaction between doctors and patients in which both actors contribute to the medical decision-making process. SDM has raised great interest in mental healthcare over the last decade, as it is considered a fundamental part of patient-centered care. However, there is no research evaluating the efficacy of SDM compared to usual care (CAU), as it relates to quality of care and more specifically treatment adherence, in bipolar disorder (BD). This is a 12-month multi-centre, cluster-randomized controlled trial comparing the efficacy of SDM to CAU. Adult BD patients (n = 300) will be eligible after stabilization for at least 4 weeks following an acute mood episode. The intervention will consist of applying the standardized SDM process as developed by the Ottawa Hospital Research Institute in order to choose the maintenance treatment of BD. A multidisciplinary team developed a decision aid "choose my long-term treatment with my doctor" for BD patients to clarify possible therapeutic options. Primary outcome will assess the patient's level of adherence (based on hetero-evaluation) of ongoing treatment at 12 months. Secondary outcomes will assess the difference between the 2 groups of patients in terms of adherence to maintenance drug therapy based on other measures (self-assessment scale and plasma levels of mood stabilizers). Additionally, other dimensions will be assessed: decisional conflict, satisfaction with care and involvement in decision making, beliefs about treatment, therapeutic relationship, knowledge about information for medical decision and clinical outcomes (depression, mania, functioning and quality of life). The primary endpoint will be analysed without adjustment by comparison of adherence scores between the two groups using Student t-tests or Mann-Whitney tests according to the variable distribution. A set of secondary analyses will be adjusted for covariates of clinical interest using generalized linear

  10. Natural genetic transformation in Acinetobacter sp. BD413 Biofilms: introducing natural genetic transformation as a tool for bioenhancement of biofilm reactors

    Energy Technology Data Exchange (ETDEWEB)

    Hendrickx, L

    2002-07-01

    This study focussed on the localization and quantification of natural genetic transformation using neutral and disadvantageous genes in monoculture biofilms to investigate gene transfer and expression of the transferred genes in the absence of a selective advantage. Data obtained by this investigation were regarded as initial steps for evaluating the applicability of adding catabolic traits into the indigenous bacterial community of biofilm reactors by in situ natural genetic transformation. Because Acinetobacter spp. strains are readily found in waste water treatment plants and because Acinetobacter sp. BD413 possesses a high effective level of competence, natural genetic transformation was investigated in monoculture Acinetobacter sp. BD413 biofilms. The genes used for transformation encoded for the green fluorescent protein (GFP) and its variants. Monitoring of transformation events were performed with the use of automated confocal laser scanning microscopy (CLSM) and semi automated digital image processing and analysis. (orig.)

  11. X-RAY OBSERVATIONS OF BOW SHOCKS AROUND RUNAWAY O STARS. THE CASE OF ζ OPH AND BD+43°3654

    Energy Technology Data Exchange (ETDEWEB)

    Toalá, J. A.; Guerrero, M. A. [Instituto de Astrofísica de Andalucía, IAA-CSIC, Glorieta de la Astronomía s/n, E-18008 Granada (Spain); Oskinova, L. M.; González-Galán, A. [Institute for Physics and Astronomy, University of Potsdam, D-14476 Potsdam (Germany); Ignace, R. [Department of Physics and Astronomy, East Tennessee State University, Johnson City, TN 37614 (United States); Pohl, M., E-mail: toala@iaa.es [Institute of Astronomy and Astrophysics, Academia Sinica (ASIAA), Taipei 10617,Taiwan (China)

    2016-04-20

    Non-thermal radiation has been predicted within bow shocks around runaway stars by recent theoretical works. We present X-ray observations toward the runaway stars ζ Oph by Chandra and Suzaku and of BD+43°3654 by XMM-Newton to search for the presence of non-thermal X-ray emission. We found no evidence of non-thermal emission spatially coincident with the bow shocks; nonetheless, diffuse emission was detected in the vicinity of ζ Oph. After a careful analysis of its spectral characteristics, we conclude that this emission has a thermal nature with a plasma temperature of T ≈ 2 × 10{sup 6} K. The cometary shape of this emission seems to be in line with recent predictions of radiation-hydrodynamic models of runaway stars. The case of BD+43°3654 is puzzling, as non-thermal emission has been reported in a previous work for this source.

  12. Development of a Real-Time PCR Protocol Requiring Minimal Handling for Detection of Vancomycin-Resistant Enterococci with the Fully Automated BD Max System.

    Science.gov (United States)

    Dalpke, Alexander H; Hofko, Marjeta; Zimmermann, Stefan

    2016-09-01

    Vancomycin-resistant enterococci (VRE) are an important cause of health care-associated infections, resulting in significant mortality and a significant economic burden in hospitals. Active surveillance for at-risk populations contributes to the prevention of infections with VRE. The availability of a combination of automation and molecular detection procedures for rapid screening would be beneficial. Here, we report on the development of a laboratory-developed PCR for detection of VRE which runs on the fully automated Becton Dickinson (BD) Max platform, which combines DNA extraction, PCR setup, and real-time PCR amplification. We evaluated two protocols: one using a liquid master mix and the other employing commercially ordered dry-down reagents. The BD Max VRE PCR was evaluated in two rounds with 86 and 61 rectal elution swab (eSwab) samples, and the results were compared to the culture results. The sensitivities of the different PCR formats were 84 to 100% for vanA and 83.7 to 100% for vanB; specificities were 96.8 to 100% for vanA and 81.8 to 97% for vanB The use of dry-down reagents and the ExK DNA-2 kit for extraction showed that the samples were less inhibited (3.3%) than they were by the use of the liquid master mix (14.8%). Adoption of a cutoff threshold cycle of 35 for discrimination of vanB-positive samples allowed an increase of specificity to 87.9%. The performance of the BD Max VRE assay equaled that of the BD GeneOhm VanR assay, which was run in parallel. The use of dry-down reagents simplifies the assay and omits any need to handle liquid PCR reagents. Copyright © 2016, American Society for Microbiology. All Rights Reserved.

  13. SPECIFIC MOOD SYMPTOMS CONFER RISK FOR SUBSEQUENT SUICIDAL IDEATION IN BIPOLAR DISORDER WITH AND WITHOUT SUICIDE ATTEMPT HISTORY: MULTI-WAVE DATA FROM STEP-BD.

    Science.gov (United States)

    Stange, Jonathan P; Kleiman, Evan M; Sylvia, Louisa G; Magalhães, Pedro Vieira da Silva; Berk, Michael; Nierenberg, Andrew A; Deckersbach, Thilo

    2016-06-01

    Little is known about specific mood symptoms that may confer risk for suicidal ideation (SI) among patients with bipolar disorder (BD). We evaluated prospectively whether particular symptoms of depression and mania precede the onset or worsening of SI, among adults with or without a history of a suicide attempt. We examined prospective data from a large (N = 2,741) cohort of patients participating in the Systematic Treatment Enhancement Program for BD (STEP-BD). We evaluated history of suicide attempts at baseline, and symptoms of depression and mania at baseline and follow-up visits. Hierarchical linear modeling tested whether specific mood symptoms predicted subsequent levels of SI, and whether the strength of the associations differed based on suicide attempt history, after accounting for the influence of other mood symptoms and current SI. Beyond overall current depression and mania symptom severity, baseline SI, and illness characteristics, several mood symptoms, including guilt, reduced self-esteem, psychomotor retardation and agitation, increases in appetite, and distractibility predicted more severe levels of subsequent SI. Problems with concentration, distraction, sleep loss and decreased need for sleep predicted subsequent SI more strongly among individuals with a suicide attempt history. Several specific mood symptoms may confer risk for the onset or worsening of SI among treatment-seeking patients with BD. Individuals with a previous suicide attempt may be at greater risk in part due to greater reactivity to certain mood symptoms in the form of SI. However, overall, effect sizes were small, suggesting the need to identify additional proximal predictors of SI. © 2016 Wiley Periodicals, Inc.

  14. The role of B/D ratio and A/D ratio to defferentiate malignancy from benignancy in distal extrahepatic bile duct obstruction

    International Nuclear Information System (INIS)

    Rhim, Hyun Chul; Baek, JUng Hwan; Jeon, Eui Yong; Koh, Byung Hee; Cho, On Koo; Kim, Young Hwan

    1994-01-01

    To determine wheter bilirubin/extrahepatic bile duct diameter ratio(B/D ratio) or alkalinephosphatase/extrahepatic bile duct diameter ratio (A/D ratio) can be used to differentiate malignant from benigndisease in distal extrahepatic bile duct obstruction during ultrasonographic examination. We retrospectively reviewed the sonograms and laboratory data of 100 patients with obstructive jaundice (benign : n=50, malignant: : n=50). The diagnosis was confirmed either surgically (n=66) or clinically (n=34). The B/D ratio and A/D radio were calculated by means of dividing total bilirubin (mg/dl) and alkaline phosphatase (I.U.)respectively by maximum extrahepatic bile duct diameter(mm) on ultrasonogram. Significant difference in B/D ratio was found between the benignancy (0.28+0.25) and malignancy (0.98+0.84) groups (P<0.001). Significant difference in A/D ratio was also found between the benignancy (15.00+10.22) and malignancy (32.44+30.28) groups(P<0.001) Accuracies to predict malignancy according to criteria of B/D and A/D ratios were less than 75% and 65%respectively. On the other hand, the positive predictive value and specificity were relatively high. The B/D ratio and A/D ratio calculated from ultrasonograms can be used as a valuable screening index todifferentiate malignancy from benignacy in patients with distal extrahepatic bile duct obstruction, especially when the sonography is difficult because of the interposition of bowel gas or obesity

  15. Does recent mania affect response to antidepressants in bipolar disorder? A re-analysis of STEP-BD data.

    Science.gov (United States)

    Mousavi, Zahra; Johnson, Sheri; Li, Descartes

    2018-08-15

    One previous study suggested that the presence of a manic episode before bipolar depression is related to worse response to antidepressants. To examine this effect in a larger sample, we used data from the large, multi-site STEP-BD study. We hypothesized that among persons treated with antidepressants for bipolar depression, manic or mixed episodes before depression onset (as compared to euthymia) would predict lower rate of recovery, more sustained depressive symptoms and higher rate of switching into mania/hypomania after antidepressant treatment of bipolar depression. 320 participants were available for analyses (140 male) diagnosed with bipolar I, bipolar II, cyclothymia, bipolar disorder not otherwise specified, or schizoaffective disorder bipolar subtype. Patients were randomly assigned to 3 treatment randomization strata (placebo, bupropion, and paroxetine) as adjuncts to mood stabilizers. Analyses were conducted to examine the effect of episode status before the depressive episode on the degree of change in depressive symptoms at 3 and 6 months, the likelihood of depression recovery and the likelihood of anti-depressant induced switching. Presence of a manic episode before depression in patients with bipolar disorder did not significantly predict response to antidepressants. The study was limited by a high rate of attrition, and consideration of only two antidepressant medications. Our findings are in agreement with other past studies suggesting that mania and depression may operate separately for those with bipolar disorder, with differential predictors of the onset and offset of mania versus depression. Future directions may consider vulnerability for these episodes separately. Copyright © 2018 Elsevier B.V. All rights reserved.

  16. Optical Photometry and X-Ray Monitoring of the ``Cool Algol'' BD +05°706: Determination of the Physical Properties

    Science.gov (United States)

    Torres, Guillermo; Mader, Jeff A.; Marschall, Laurence A.; Neuhäuser, Ralph; Duffy, Alaine S.

    2003-06-01

    We present new photometric observations in the BVRI bands of the double-lined eclipsing binary BD +05°706 conducted over three observing seasons, as well as new X-ray observations obtained with ROSAT covering a full orbital cycle (P=18.9 days). A detailed light-curve analysis of the optical data shows the system to be semidetached, confirming indications from an earlier analysis by Torres et al. (published in 1998), with the less massive and cooler star filling its Roche lobe. The system is a member of the rare class of cool Algol systems, which are different from the ``classical'' Algol systems in that the mass-gaining component is also a late-type star rather than a B- or A-type star. By combining the new photometry with a reanalysis of the spectroscopic observations reported by Torres et al., we derive accurate absolute masses for the components of M1=2.633+/-0.028 Msolar and M2=0.5412+/-0.0093 Msolar, radii of R1=7.55+/-0.20 Rsolar and R2=11.02+/-0.21 Rsolar, as well as effective temperatures of 5000+/-100 and 4640+/-150 K, for the primary and secondary, respectively. There are obvious signs of activity (spottedness) in the optical light curve of the binary. Our X-ray light curve clearly shows the primary eclipse but not the secondary eclipse, suggesting that the primary star is the dominant source of the activity in the system. The depth and duration of the eclipse allow us to infer some of the properties of the X-ray-emitting region around that star.

  17. Evaluation of the BD Vacutainer Plus Urine C&S Preservative Tubes compared with nonpreservative urine samples stored at 4°C and room temperature.

    Science.gov (United States)

    Eisinger, Stephen W; Schwartz, Matthew; Dam, Lisa; Riedel, Stefan

    2013-09-01

    The stability of urine specimens submitted for culture remains a challenge for many laboratories because of delays in specimen transport. We evaluated the usefulness of BD Vacutainer Plus Urine C&S Preservative Tube in ensuring specimen stability. Clinical urine specimens collected in sterile collection cups (n = 110) were plated onto sheep blood and MacConkey agar following standard laboratory procedures guidelines. Thereafter, specimens were divided into 3 storage conditions: nonpreservative, refrigerated; nonpreservative, room temperature (RT); BD Vacutainer Plus Urine C&S Preservative Tube, RT. For each sample type, additional cultures were set up at 2, 4, 24, and 48 hours. Initially, 18 specimens had no growth, 32 showed mixed skin flora, and 60 yielded at least 1 uropathogen. Increased colony counts of uropathogens were observed for nonpreserved urine samples stored at RT; these changes were statistically significant. Minor differences between refrigerated urine samples and BD Vacutainer Plus Urine C&S Preservative Tube samples were seen but were not statistically significant. The use of preservative-containing collection tubes is desirable to ensure specimen stability when prompt processing or refrigeration is not feasible.

  18. The effectiveness of BD Vacutainer® Plus Urinalysis Preservative Tubes in preservation of urine for chemical strip analysis and particle counting.

    Science.gov (United States)

    Ekşioğlu, Merve Kaymak; Madenci, Özlem Çakır; Yücel, Nihal; Elçi, Abdullah; Turhan, Bülent; Orhan, Gani; Orçun, Asuman

    2016-01-01

    The aim of this study was to evaluate the stability of urine collected in preservative tubes for chemistry strip analyses and particle counting to determine whether the transport of urine samples with all of their constituents is possible. 275 pathologic urine specimens were included. Each urine sample was evaluated after 4, 8, 12, 24, and 48 hours of storage in BD Vacutainer(®) Plus Urinalysis Preservative (BD UAP) tubes and compared with refrigeration at 4 °C. All analyses were peformed on H-800 and FUS-200 automatic modular urine analyzers (Dirui Industry, Changchun, China). The kappa coefficients (κ), false positive (FP) and false negative (FN) rates were evaluated. κ > 0.8 was accepted as good agreement. Haemoglobin (Hb), leucocyte esterase (LE), and protein (Pro) analyses should be performed within 4 hours, whereas glucose (Glc) was stable until the end of 48 hours in both storage conditions. Nitrite (Nit) was well preserved in BD UAP tubes for 24 hours but was stable only up to 8 hours at 4 °C. Bilirubin (Bil) had very high FN rates even at 4 hours in both conditions. The particle counting showed high FN rates for white blood cells (WBC) and red blood cells (RBC), whereas squamous epithelial cells (EC) were stable up to 8 hours in both conditions. Preanalytical requirements for both urine chemical strip analyses and particle counting in a unique sample were not met in either condition. Thus, the transfer of urine samples for centralization of urinalysis is not yet feasible.

  19. The detection and differentiation of methicillin-resistant and methicillin-susceptible Staphylococcus aureus endocarditis by using the BD GeneOhm StaphSR Assay.

    Science.gov (United States)

    Frey, Amy B; Wilson, Deborah A; LaSalvia, Margaret M; Tan, Carmela D; Rodriguez, E Rene; Shrestha, Nabin K; Hall, Gerri S; Procop, Gary W

    2011-11-01

    We use the BD GeneOhm StaphSR Assay (BD Diagnostics, Oakville, Canada) to screen for Staphylococcus aureus nasal colonization and sought to evaluate this assay for the assessment of valve specimens from patients with endocarditis. We examined 23 paired fresh and formalin-fixed, paraffin-embedded cardiac valve tissue samples, 12 of which had S aureus endocarditis, using the BD GeneOhm StaphSR Assay for the detection and differentiation of methicillin-susceptible and methicillin-resistant S aureus. This assay appropriately characterized all specimens with respect to the presence or absence of S aureus. There was an 87.5% correlation between the presence or absence of the mecA gene and the oxacillin susceptibility results for the S aureus isolates studied. The GeneOhm StaphSR assay accurately detected S aureus in cardiac valve tissue samples. Rare discordances were observed between oxacillin susceptibility status and mecA gene detection by this assay.

  20. Svingningsteori, Bd. 1

    DEFF Research Database (Denmark)

    Nielsen, Søren R. K.

    Nærværende lærebog er skrevet med henblik på undervisningen i lineær svingingsteori på konstruktionsliniens 8. semester på Aalborg Universitetscenter. Det pågældende kursus danner grundlaget for efterfølgende undervisning i ikke-lineær svingningsteori, hvilket har påvirket fremstillingens form. D...

  1. Determination of Henry's constant, the dissociation constant, and the buffer capacity of the bicarbonate system in ruminal fluid.

    Science.gov (United States)

    Hille, Katharina T; Hetz, Stefan K; Rosendahl, Julia; Braun, Hannah-Sophie; Pieper, Robert; Stumpff, Friederike

    2016-01-01

    Despite the clinical importance of ruminal acidosis, ruminal buffering continues to be poorly understood. In particular, the constants for the dissociation of H2CO3 and the solubility of CO2 (Henry's constant) have never been stringently determined for ruminal fluid. The pH was measured in parallel directly in the rumen and the reticulum in vivo, and in samples obtained via aspiration from 10 fistulated cows on hay- or concentrate-based diets. The equilibrium constants of the bicarbonate system were measured at 38°C both using the Astrup technique and a newly developed method with titration at 2 levels of partial pressure of CO2 (pCO2; 4.75 and 94.98 kPa), yielding mean values of 0.234 ± 0.005 mmol ∙ L(-1) ∙ kPa(-1) and 6.11 ± 0.02 for Henry's constant and the dissociation constant, respectively (n/n = 31/10). Both reticular pH and the pH of samples measured after removal were more alkalic than those measured in vivo in the rumen (by ΔpH = 0.87 ± 0.04 and 0.26 ± 0.04). The amount of acid or base required to shift the pH of ruminal samples to 6.4 or 5.8 (base excess) differed between the 2 feeding groups. Experimental results are compared with the mathematical predictions of an open 2-buffer Henderson-Hasselbalch equilibrium model. Because pCO2 has pronounced effects on ruminal pH and can decrease rapidly in samples removed from the rumen, introduction of a generally accepted protocol for determining the acid-base status of ruminal fluid with standard levels of pCO2 and measurement of base excess in addition to pH should be considered. Copyright © 2016 American Dairy Science Association. Published by Elsevier Inc. All rights reserved.

  2. Temperature profile and water depth data collected from USS HENRY B. WILSON using BT and XBT casts in the Indian Ocean and other seas from 22 October 1986 to 26 November 1986 (NODC Accession 8800183)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Temperature profile and water depth data were collected using BT and XBT casts from the USS HENRY B. WILSON in the Indian Ocean, Gulf of Oman, Gulf of Iran, and...

  3. [Crusading and chronicle writing on the medieval Baltic frontier : a companion to the Chronicle of Henry of Livonia. Hrsg. von Marek Tamm, Linda Kaljundi, Carsten Selch Jensen] / Volker Honemann

    Index Scriptorium Estoniae

    Honemann, Volker, 1943-

    2013-01-01

    Arvustus: Crusading and chronicle writing on the medieval Baltic frontier : a companion to the Chronicle of Henry of Livonia. Hrsg. von Marek Tamm, Linda Kaljundi, Carsten Selch Jensen. Verlag Ashgate. Farnham, 2011

  4. HENRY CHARLES LEA Y SU RED DE COLABORADORES LATINOAMERICANOS: RAZONES PARA ESTUDIAR EL SANTO OFICIO EN LA SEGUNDA MITAD DEL SIGLO XIX

    Directory of Open Access Journals (Sweden)

    Doris Moreno

    2013-12-01

    Full Text Available Se aborda en este artículo la vida y pensamiento de Henry Charles Lea en relación a sus estudios sobre la historia de la Inquisición española. Se esboza brevemente la red de colaboradores que Lea estableció en toda Latinoamérica así como su perfil político e intelectual, subrayando su importancia para la escritura de la obra The Inquisition in the Spanish Dependencies (1908. Finalmente, se plantean los motivos que llevaron a estos intelectuales a colaborar intensamente con el historiador norteamericano en el marco de los procesos de construcción de identidades sociales y políticas en Latinoamérica en la segunda mitad del siglo XIX. Se toma como eje conductor de este planteamiento la correspondencia de Juan María Gutiérrez con Henry Charles Lea.

  5. Ensaios teóricos: os capitulos introdutórios de Henry Fielding Exploring theory: Fielding’s prefatory chapters

    Directory of Open Access Journals (Sweden)

    Sandra Guardini T. Vasconcelos

    2000-01-01

    Full Text Available Henry Fielding, um dos fundadores do romance inglês, deixou um material teórico bastante rico a respeito do gênero em ascensão, que ele discutiu em prefácios e nos célebres capítulos introdutórios a Tom Jones. Esse artigo tem como objetivo apresentar alguns dos impasses e dilemas enfrentados pelo romancista e as soluções formais que ele propôs para resolvê-los.Henry Fielding, one of the founders of the English novel, has left a wealth theoretical material about the rising genre, which he discussed in prefaces and in his famous introductory chapters to Tom Jones, this article aims to present some of the impasses and double binds faced by the novelist and the formal solutions he proposed to deal with them.

  6. La France au Tsar : chanson patriotique créée par Marius Richard à la Scala, Henri Helme à Ba-ta-clan [illustration couleurs Donjean

    OpenAIRE

    François Bigot Éditeur , .; Daphy , Éliane

    2010-01-01

    La France au Tsar : chanson patriotique créée par Marius Richard à la Scala, Henri Helme à Ba-ta-clan ; paroles de Lucien Colonge, Musique de J. Claudel. [Illustration couleurs signée] Donjean. A la chanson populaire, Maison Bigot éditeur (sans cotage, sans ©, datation recherche en cours). Titre inconnu du catalogue BNF. Datation provisoire par année de dépôt médihal (2010)

  7. Human radiation studies: Remembering the early years: Oral history of radiologist Henry I. Kohn, M.D., Ph.D., conducted September 13, 1994

    International Nuclear Information System (INIS)

    1995-06-01

    This report is a transcript of an interview of Dr. Henry I. Kohn by representatives of the US DOE Office of Human Radiation Experiments. Dr. Kohn was selected for this interview because of the positions he held at Oak Ridge National Laboratory, University of California at San Francisco, and Harvard Medical School. Dr. Kohn discussed his remembrances of his experiences in blood chemistry of animals and patients exposed to radiation, and his remembrances of several radiobiologists

  8. Seeing Water in Early Twentieth-Century Mexico City: Henry Wellge's Perspective Plan of the City and Valley of Mexico, D.F. 1906

    OpenAIRE

    Widdifield, Stacie G.; Banister, Jeffrey M.

    2015-01-01

    We examine Henry Wellge's 1906 chromolithograph, Perspective Plan of the City and Valley of Mexico, D.F., a panoramic view that organizes the capital and its lacustrine environs through close up and distant perspectives. The Plan depicts a landscape integrated by canals, rivers, and lakes, recording a pivotal moment before modern hydraulic infrastructure would remove surface water from view. We thus interrogate this image as a visual register of hydraulic-control ideals in vogue around 1900, ...

  9. [Charles-Henri Fialon (1846-1933), creator of the Museum of the Faculty of Pharmacy of Paris. His family and professional life].

    Science.gov (United States)

    Flahaut, Jean

    2004-01-01

    Henri Fialon was pharmacist in 1871, and worked in the family apothecary, at Rueil near Paris. At 46 years, he stopped his pharmaceutical activity, and livre quietly, being specially interested by the ancient pharmaceutical pots. He realized a very important collection, which he gave to the French Society of Pharmaceutical History. A museum was installed at the Faculty of Pharmacy of Paris which is presently in the Guillaume Valette Gallery and contains more than 500 pieces.

  10. Putting Media Literacy Education in Perspective of Theory of "Participatory Culture" : The case of Henry Jenkins (2009) Confronting the Challenges of Participatory Culture

    OpenAIRE

    Sunagawa, Seiji

    2010-01-01

    In this report, I took a viewpoint of the "participatory culture" of Henry Jenkins (2009) into account and argued what the literacy of the digital media. I clarified what kind of culture "participatory culture" is and what one participated with how. The support system between peers in the "participatory culture", have the community which can feel relieved where the system letting each other take an equal viewpoint. I made clear that it was a problem of the media literacy education how to buil...

  11. [Jörg Zägel (in Zusammenarbeit mit Reiner Steinweg). Vergangenheitsdiskurse in der Ostseeregion. Bd. 1. Auseinandersetzungen in den nordischen Staaten über Krieg. Völkermord, Diktatur, Besatzung und Vertreibung; B. 2 : Die Sicht auf Krieg, Diktat

    Index Scriptorium Estoniae

    Hecker-Stampehl, Jan

    2011-01-01

    Arvustus : Jörg Zägel (in Zusammenarbeit mit Reiner Steinweg). Vergangenheitsdiskurse in der Ostseeregion. Bd. 1. Auseinandersetzungen in den nordischen Staaten über Krieg. Völkermord, Diktatur, Besatzung und Vertreibung. Berlin : LIT Verlag, 2007. (Kieler Schriften zur Friedenswissenschaft. 14); Bd. 2 : Die Sicht auf Krieg, Diktatur, Völkermord, Besatsung und Vertreibung in Russland, Polen und den baltischen Staaten. Berlin: Lit Verlag, 2007. (Kieler Schriften zur Friedenswissenschaft. 15)

  12. The human and the inhuman: visual culture, political culture, and the images produced by George Rodger and Henri Cartier-Bresson in the Nazi concentration camps

    Directory of Open Access Journals (Sweden)

    Erika Cazzonatto Zerwes

    2016-08-01

    Full Text Available This article aims to grasp some aspects of the notion of humanism in photography and its closeness to the political culture and the visual culture in the period, through the specific experiences of George Rodger and Henri Cartier-Bresson, two photographers who were first-hand witnesses and provided accounts of horror in the Nazi concentration camps at the end of World War II. George Rodger photographed the Bergen-Belsen camp as soon as it was liberated by the British troops. Henri Cartier-Bresson was there with a film crew recording the deported masses newly freed from the Nazi concentration and extermination camps. These experiences came to have profound impact on the biography and work of both of them. In the two cases, there is a notion of humanism linked to World War II events, which is observed in photography and photographic representation, and it has a significant consequence for the contemporary visual culture.   Keywords: Visual Culture; Political Culture; War Photography; Photojournalism; Concentration Camps.   Original title: O humano e o desumano: cultura visual, cultura política e as imagens feitas por George Rodger e Henri Cartier-Bresson nos campos de concentração nazistas.

  13. Daily Management System of the Henry Ford Production System: QTIPS to Focus Continuous Improvements at the Level of the Work.

    Science.gov (United States)

    Zarbo, Richard J; Varney, Ruan C; Copeland, Jacqueline R; D'Angelo, Rita; Sharma, Gaurav

    2015-07-01

    To support our Lean culture of continuous improvement, we implemented a daily management system designed so critical metrics of operational success were the focus of local teams to drive improvements. We innovated a standardized visual daily management board composed of metric categories of Quality, Time, Inventory, Productivity, and Safety (QTIPS); frequency trending; root cause analysis; corrective/preventive actions; and resulting process improvements. In 1 year (June 2013 to July 2014), eight laboratory sections at Henry Ford Hospital employed 64 unique daily metrics. Most assessed long-term (>6 months), monitored process stability, while short-term metrics (1-6 months) were retired after successful targeted problem resolution. Daily monitoring resulted in 42 process improvements. Daily management is the key business accountability subsystem that enabled our culture of continuous improvement to function more efficiently at the managerial level in a visible manner by reviewing and acting based on data and root cause analysis. Copyright© by the American Society for Clinical Pathology.

  14. Mortality disparities among groups participating in an East Africa surveying expedition: the Herbert Henry Austin expedition of 1900-1901.

    Science.gov (United States)

    Imperato, Pascal James; Imperato, Gavin H; Imperato, Austin C

    2013-10-01

    In the late nineteenth and early twentieth centuries, a number of European expeditions traveled to the region of Lake Rudolf, now largely in northern Kenya. Although diverse in intent, many of these were undertaken in the interests of furthering colonial territorial claims. In 1900-1901, Major Herbert Henry Austin led a British expedition down to the lake from Khartoum in the north. Of the 62 African, Arab, and European members of this expedition, only 18 (29 %) arrived at its final destination at Lake Baringo in Kenya. Because of a confluence of adverse climatic, social, and political conditions, the expedition ran short of food supplies when it arrived at the northern end of the lake in April 1901. For the next 4 months, the members of the expedition struggled down the west side of the lake and beyond. The greatest mortality (91 %) occurred among the 32 African transport drivers who were the most marginally nourished at the outset of the trip. The lowest mortality among the Africans on the expedition (15 %) occurred among the members of the Tenth Sudanese Rifles Battalion, who had an excellent nutritional status at the start of the expedition. Major Austin himself suffered from severe scurvy with retinal hemorrhages which left him partially blind in his right eye. An analysis of the mortality rates among the groups that participated in this expedition was undertaken. This revealed that poor nutritional status at the start of the trip was predictive of death from starvation.

  15. Deviation Management: Key Management Subsystem Driver of Knowledge-Based Continuous Improvement in the Henry Ford Production System.

    Science.gov (United States)

    Zarbo, Richard J; Copeland, Jacqueline R; Varney, Ruan C

    2017-10-01

    To develop a business subsystem fulfilling International Organization for Standardization 15189 nonconformance management regulatory standard, facilitating employee engagement in problem identification and resolution to effect quality improvement and risk mitigation. From 2012 to 2016, the integrated laboratories of the Henry Ford Health System used a quality technical team to develop and improve a management subsystem designed to identify, track, trend, and summarize nonconformances based on frequency, risk, and root cause for elimination at the level of the work. Programmatic improvements and training resulted in markedly increased documentation culminating in 71,641 deviations in 2016 classified by a taxonomy of 281 defect types into preanalytic (74.8%), analytic (23.6%), and postanalytic (1.6%) testing phases. The top 10 deviations accounted for 55,843 (78%) of the total. Deviation management is a key subsystem of managers' standard work whereby knowledge of nonconformities assists in directing corrective actions and continuous improvements that promote consistent execution and higher levels of performance. © American Society for Clinical Pathology, 2017. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com

  16. Urban common space, heterotopia and the right to the city: Reflections on the ideas of Henri Lefebvre and David Harvey

    Directory of Open Access Journals (Sweden)

    Orlando Alves dos Santos Junior

    2014-05-01

    Full Text Available A city’s common spaces are appropriated by capital that aims to guarantee the conditions necessary for the production-reproduction of capitalist relations. In this context, the challenge is to imagine and construct a very different type of city capable of breaking away from the dynamic of capital, founded on new forms of appropriation of the city, which implies articulating both theory and praxis. For this to occur, however, it is necessary to create new knowledge about the city and a strong anti-capitalist social movement focused on the transformation of daily urban life and involving new forms of appropriation of urban common spaces. It is in this context, and from a dialectic perspective, that this article articulates the ideas of Henri Lefebvre and David Harvey, seeking to contribute to an understanding of the production processes of space in contemporary capitalism, the discussion of the future of cities and perspectives on transition. To do so, the article addresses four central ideas: (i the dialectic conception of space to problematize the production and appropriation of urban common spaces; (ii the recognition of urban common spaces as spaces traversed by contradictions, disputes and material and symbolic conflicts among different agents; (iii the right to the city as a need and as a utopian project; and (iv the challenge of articulating heterotopic practices from the perspective of creative rebellion for the right to the city and the transition to a new urban future.

  17. Multilayer, Stacked Spiral Copper Inductors on Silicon with Micro-Henry Inductance Using Single-Level Lithography

    Directory of Open Access Journals (Sweden)

    Timothy Reissman

    2012-01-01

    Full Text Available We present copper structures composed of multilayer, stacked inductors (MLSIs with tens of micro-Henry inductance for use in low frequency (sub 100 MHz, power converter technology. Unique to this work is the introduction of single-level lithography over the traditional two-level approach to create each inductor layer. The result is a simplified fabrication process which results in a reduction in the number of lithography steps per inductor (metal layer and a reduction in the necessary alignment precision. Additionally, we show that this fabrication process yields strong adhesion amongst the layers, since even after a postprocess abrasion technique at the inner diameter of the inductors, no shearing occurs and connectivity is preserved. In total, three separate structures were fabricated using the single-level lithography approach, each with a three-layered, stacked inductor design but with varied geometries. Measured values for each of the structures were extracted, and the following results were obtained: inductance values of 24.74, 17.25, and 24.74 μH, self-resonances of 9.87, 5.72, and 10.58 MHz, and peak quality factors of 2.26, 2.05, and 4.6, respectively. These values are in good agreement with the lumped parameter model presented.

  18. L’individu comme problème phénoménologique chez Hannah Arendt et Michel Henry

    Directory of Open Access Journals (Sweden)

    Jan Cerny

    2012-12-01

    Full Text Available Cette étude, dans un premier temps, apporte des preuves à la possibilité d’interpréter la pensée politique de Hannah Arendt comme un projet phénoménologique original dont le but est d’élever l’apparence de la personne au rang de mode unique de l’apparaître. Puis elle présente brièvement la phénoménologie matérielle de Michel Henry dans laquelle le Soi individuel joue un rôle tout aussi central, puisqu’il est la condition de l’apparence de la vie et le fondement de tout apparaître. En conclusion, l’étude esquisse les conséquences d’une telle position privilégiée du sujet individuel pour la conception théorique de la réalité effective de l’apparaître, de même que pour les problèmes pratiques de l’action de l’homme dans le monde.

  19. Architectural creativity of Alexander Bernardazzi and Henry Lonsky in Kishinev during the second half of the XIXth century

    Directory of Open Access Journals (Sweden)

    Chastina

    2017-10-01

    Full Text Available During the period following 1873, when Bessarabia was a province of the Russian Empire, the architecture of this period was dominated by a mixture of several historical styles and directions, the so-called “eclectic” stage. The creativity of leading architects such as Alexander Bernardazzi and Henry Lonsky was the most evident at that time. The image of the city of Kishinev became more eclectic and it was reflected in the buildings of the railway station and the passenger hall, the city club, the county court, the Noble Assembly, the winemaking school, all of which were built according to the designs of these architects in the second half of the XIX century. At that time, a question relative to the necessity of new theatre building in Kishinev was of a particular interest. In 1889 the Kishinev City Head Karl Schmidt proposed to construct a temporary theatre with beautiful facade, together with the fact that in size it could satisfy the needs of city for the next 15-20 years. And he appealed to the city architects, including A. Bernardazzi and H. Lonsky to present their views at this important problem. The author writes this article on the basis of the archival documents which present the history of the construction of various buildings and the creative activity of the architects. This is reflected through the prism of that era with a high level of development and methods of construction equipment, as well as with the artistic principles characteristic of that period.

  20. Inverse modeling for seawater intrusion in coastal aquifers: Insights about parameter sensitivities, variances, correlations and estimation procedures derived from the Henry problem

    Science.gov (United States)

    Sanz, E.; Voss, C.I.

    2006-01-01

    Inverse modeling studies employing data collected from the classic Henry seawater intrusion problem give insight into several important aspects of inverse modeling of seawater intrusion problems and effective measurement strategies for estimation of parameters for seawater intrusion. Despite the simplicity of the Henry problem, it embodies the behavior of a typical seawater intrusion situation in a single aquifer. Data collected from the numerical problem solution are employed without added noise in order to focus on the aspects of inverse modeling strategies dictated by the physics of variable-density flow and solute transport during seawater intrusion. Covariances of model parameters that can be estimated are strongly dependent on the physics. The insights gained from this type of analysis may be directly applied to field problems in the presence of data errors, using standard inverse modeling approaches to deal with uncertainty in data. Covariance analysis of the Henry problem indicates that in order to generally reduce variance of parameter estimates, the ideal places to measure pressure are as far away from the coast as possible, at any depth, and the ideal places to measure concentration are near the bottom of the aquifer between the center of the transition zone and its inland fringe. These observations are located in and near high-sensitivity regions of system parameters, which may be identified in a sensitivity analysis with respect to several parameters. However, both the form of error distribution in the observations and the observation weights impact the spatial sensitivity distributions, and different choices for error distributions or weights can result in significantly different regions of high sensitivity. Thus, in order to design effective sampling networks, the error form and weights must be carefully considered. For the Henry problem, permeability and freshwater inflow can be estimated with low estimation variance from only pressure or only

  1. Do gesto ao símbolo: a teoria de Henri Wallon sobre a formação simbólica From gesture to symbol: the theory of Henri Wallon about symbolic formation

    Directory of Open Access Journals (Sweden)

    Dener Luiz da Silva

    2007-01-01

    Full Text Available Henri Wallon, filósofo, médico e psicólogo francês, contribuiu para a psicologia não apenas com uma teoria da emoção ou ainda com suas discussões e divergências com Jean Piaget. Dentre suas contribuições pouco discutidas estão sua teoria sobre a inteligência, suas discussões sobre a origem e o desenvolvimento do pensamento discursivo nas crianças e, talvez menos conhecidas, suas reflexões e proposições sobre a transição entre uma inteligência sensório-motora (caracterizada pela capacidade de resolver problemas práticos, mas sem o auxílio da reflexão e uma outra, inteligência discursiva (caracterizada pela utilização e intermediação dos símbolos e representações. Sabe-se que sua proposição para essa transição, diversamente de Piaget, que ressalta a continuidade e a preparação do simbólico pelo esquematismo sensório-motor, é marcada justamente pela não continuidade entre uma inteligência e outra, pela intromissão de fatores externos tais como a cultura, o social e a linguagem, e pela complexa interação entre todos esses fatores. Para melhor compreender a proposta walloniana sobre a formação do símbolo é necessário, pois, que ingressemos na sua teoria como um todo, buscando decifrar seus conceitos de emoção, comportamento simbólico, inteligência, fatores de desenvolvimento e outros. Em uma sociedade como a nossa, baseada no comportamento simbólico, entender como se dá, qual a origem e o desenvolvimento do pensamento simbólico podem ser conhecimentos de grande valia.Henri Wallon, French philosopher, physician, and psychologist, has given psychology contribution not only with his emotion theory and with his arguments and disagreements with Jean Piaget. Among his less discussed contributions are the theory about intelligence, the discussions about the origin and development in children's discoursing thought, and, maybe less known, the reflections and propositions about the transition between

  2. Radiation therapy of epidemic kaposi sarcoma: the Henri-Mondor hospital experience (643 patients); Radiotherapie du sarcome de kaposi epidemique: l`experience de l`hopital Henri-Mondor (643 patients)

    Energy Technology Data Exchange (ETDEWEB)

    Belembaogo, E; Kirova, Y; Frikha, H; Yu, S; Piedbois, P; Le Bourgeois, J P [Hopital Henri-Mondor, 94 - Creteil (France). Dept. de cancerologie

    1998-01-01

    From June 1986 to December 1996, 643 patients presenting with acquired immunodeficiency syndrome (AIDS)-related epidemic Kaposi`s sarcoma were treated with irradiation at the Oncology Department of Henri Mondor University Hospital. Three-hundred eighty-seven patients (60 %) had previously received a treatment with interferon (259 patients, 40.2 %), vinblastine (225 patients, 34.5 %), doxorubicin (22 patients, 3.4 %), bleomycin (19 patients, 2.9 %), and/or antiviral treatment (216, 33.5 %). The radiotherapy was delivered by 4 MeV OR 8 MeV electron beam for extended cutaneous fields and 45-100 kV x-ray for localized fields. The delivered dose was 20 Gy in 2 weeks (2.5 Gy/fraction, 4 fractions/week) followed by 2 weeks rest and second series of 10 Gy in 1 week. For oral cavity lesions, we used a series of 15.2 Gy was delivered (1.9 Gy/fraction, 4 fractions/week), followed for three patients by a 3 week rest and by a similar second series of 15.2 Gy.Six-hundred and twenty-one patients were evaluable and the objective response rate was 92 %, with e complete regression of clinical and functional symptoms for all patients. The skin tolerance was good, with 7.3 % grade I reactions, 69.3 % of grade II reactions, and 23.4 % grade III reactions. There was a correlation between recurrence rate and the occurrence of opportunistic infections. This analysis shows the efficacy of dose radiotherapy for treatment of epidemic Kaposi sarcoma. (author)

  3. Influence of centrifugation conditions on the results of 77 routine clinical chemistry analytes using standard vacuum blood collection tubes and the new BD-Barricor tubes.

    Science.gov (United States)

    Cadamuro, Janne; Mrazek, Cornelia; Leichtle, Alexander B; Kipman, Ulrike; Felder, Thomas K; Wiedemann, Helmut; Oberkofler, Hannes; Fiedler, Georg M; Haschke-Becher, Elisabeth

    2018-02-15

    Although centrifugation is performed in almost every blood sample, recommendations on duration and g-force are heterogeneous and mostly based on expert opinions. In order to unify this step in a fully automated laboratory, we aimed to evaluate different centrifugation settings and their influence on the results of routine clinical chemistry analytes. We collected blood from 41 healthy volunteers into BD Vacutainer PST II-heparin-gel- (LiHepGel), BD Vacutainer SST II-serum-, and BD Vacutainer Barricor heparin-tubes with a mechanical separator (LiHepBar). Tubes were centrifuged at 2000xg for 10 minutes and 3000xg for 7 and 5 minutes, respectively. Subsequently 60 and 21 clinical chemistry analytes were measured in plasma and serum samples, respectively, using a Roche COBAS instrument. High sensitive Troponin T, pregnancy-associated plasma protein A, ß human chorionic gonadotropin and rheumatoid factor had to be excluded from statistical evaluation as many of the respective results were below the measuring range. Except of free haemoglobin (fHb) measurements, no analyte result was altered by the use of shorter centrifugation times at higher g-forces. Comparing LiHepBar to LiHepGel tubes at different centrifugation setting, we found higher lactate-dehydrogenase (LD) (P = 0.003 to centrifuged at higher speed (3000xg) for a shorter amount of time (5 minutes) without alteration of the analytes tested in this study. When using LiHepBar tubes for blood collection, a separate LD reference value might be needed.

  4. A roadmap to control penguin effects in B_d"0→J/ψK_S"0 and B_s"0→J/ψϕ

    International Nuclear Information System (INIS)

    Bruyn, Kristof De; Fleischer, Robert

    2015-01-01

    Measurements of CP violation in B_d"0→J/ψK_S"0 and B_s"0→J/ψϕ decays play key roles in testing the quark-flavour sector of the Standard Model. The theoretical interpretation of the corresponding observables is limited by uncertainties from doubly Cabibbo-suppressed penguin topologies. With continuously increasing experimental precision, it is mandatory to get a handle on these contributions, which cannot be calculated reliably in QCD. In the case of the measurement of sin 2β from B_d"0→J/ψK_S"0, the U-spin-related decay B_s"0→J/ψK_S"0 offers a tool to control the penguin effects. As the required measurements are not yet available, we use data for decays with similar dynamics and the SU(3) flavour symmetry to constrain the size of the expected penguin corrections. We predict the CP asymmetries of B_s"0→J/ψK_S"0 and present a scenario to fully exploit the physics potential of this decay, emphasising also the determination of hadronic parameters and their comparison with theory. In the case of the benchmark mode B_s"0→J/ψϕ used to determine the B_s"0-B-bar_s"0 mixing phase ϕ_s the penguin effects can be controlled through B_d"0→J/ψρ"0 and B_s"0→J/ψ ( K)-bar "∗"0 decays. The LHCb collaboration has recently presented pioneering results on this topic. We analyse their implications and present a roadmap for controlling the penguin effects.

  5. Long-Term Stability of Human Genomic and Human Papillomavirus DNA Stored in BD SurePath and Hologic PreservCyt Liquid-Based Cytology Media

    Science.gov (United States)

    Agreda, Patricia M.; Beitman, Gerard H.; Gutierrez, Erin C.; Harris, James M.; Koch, Kristopher R.; LaViers, William D.; Leitch, Sharon V.; Maus, Courtney E.; McMillian, Ray A.; Nussbaumer, William A.; Palmer, Marcus L. R.; Porter, Michael J.; Richart, Gregory A.; Schwab, Ryan J.

    2013-01-01

    We evaluated the effect of storage at 2 to 8°C on the stability of human genomic and human papillomavirus (HPV) DNA stored in BD SurePath and Hologic PreservCyt liquid-based cytology media. DNA retained the ability to be extracted and PCR amplified for more than 2.5 years in both medium types. Prior inability to detect DNA in archived specimens may have been due to failure of the extraction method to isolate DNA from fixed cells. PMID:23678069

  6. Validade da equação de Henry e Rees que estima a taxa metabólica de repouso em adolescentes masculinos Validez de la ecuación de Henry y Rees que estima la tasa metabólica de reposo en adolescentes masculinos Validity of the equation of Henry and Rees that estimates the resting metabolic rate in male adolescents

    Directory of Open Access Journals (Sweden)

    Paulo Henrique S. Fonseca

    2011-06-01

    Full Text Available OBJETIVO: Analisar a validade da equação de predição da taxa metabólica de repouso proposta por Henry e Rees (1991 em adolescentes do sexo masculino. MÉTODOS: Estudo transversal, com amostra de conveniência constituída de 52 meninos, entre dez e 17 anos, sendo mensuradas a massa corporal e a calorimetria indireta. A massa corporal foi substituída na equação de Henry e Rees para determinar a taxa metabólica de repouso predita. A calorimetria indireta foi determinada pelos valores do consumo de O2 e produção de CO2, e usada na equação de Weir (1949, considerada método padrão para o cálculo da taxa metabólica de repouso. Todas as medidas foram realizadas pela manhã, com o indivíduo em jejum de seis horas, em posição supina e em repouso muscular. Realizaram-se os seguintes procedimentos estatísticos: teste t pareado; erro constante (com diferença aceita entre as médias OBJETIVO: Analizar la validez de la ecuación de predicción de la tasa metabólica de reposo (TMR propuesta por Henry y Rees (1991 en adolescentes del sexo masculino. MÉTODOS: Estudio transversal, con muestra de conveniencia constituida por 52 niños, entre 10 y 17 años, siendo medidas las variables a continuación: masa corporal y calorimetría indirecta (CI. La masa corporal fue sustituida en la ecuación de Henry y Rees (1991 para determinar la TMR predicha. La CI fue determinada por los valores del consumo de O2 y producción de CO2 y usada en la ecuación de Weir (1949, considerada como método estándar de la TMR. Todas las medidas fueron realizadas por la mañana, con el individuo en ayuno de 6 horas, en posición supina y en reposo muscular. Se realizaron los siguientes procedimientos estadísticos: prueba “t” pareada; error constante (EC - con diferencia aceptada entre los promedios menor que 5% y, para análisis de la concordancia entre los dos métodos, el procedimiento gráfico de Bland y Altman. RESULTADOS: La ecuación propuesta por

  7. Evidence of a massive planet candidate orbiting the young active K5V star BD+20 1790

    Science.gov (United States)

    Hernán-Obispo, M.; Gálvez-Ortiz, M. C.; Anglada-Escudé, G.; Kane, S. R.; Barnes, J. R.; de Castro, E.; Cornide, M.

    2010-03-01

    Context. BD+20 1790 is a young active, metal-rich, late-type K5Ve star. We have undertaken a study of stellar activity and kinematics for this star over the past few years. Previous results show a high level of stellar activity, with the presence of prominence-like structures, spots on the surface, and strong flare events, despite the moderate rotational velocity of the star. In addition, radial velocity variations with a semi-amplitude of up to 1 km s-1 were detected. Aims: We investigate the nature of these radial velocity variations, in order to determine whether they are due to stellar activity or the reflex motion of the star induced by a companion. Methods: We have analysed high-resolution echelle spectra by measuring stellar activity indicators and computing radial velocity (RV) and bisector velocity spans. Two-band photometry was also obtained to produce the light curve and determine the photometric period. Results: Based upon the analysis of the bisector velocity span, as well as spectroscopic indices of chromospheric indicators, Ca ii H & K, Hα, and taking the photometric analysis into account, we report that the best explanation for the RV variation is the presence of a substellar companion. The Keplerian fit of the RV data yields a solution for a close-in massive planet with an orbital period of 7.78 days. The presence of the close-in massive planet could also be an interpretation for the high level of stellar activity detected. Since the RV data are not part of a planet search programme, we can consider our results as a serendipitous evidence of a planetary companion. To date, this is the youngest main sequence star for which a planetary candidate has been reported. Based on observations collected at the German-Spanish Astronomical Center, Calar Alto, jointly operated by the Max-Planck-Institut für Astronomie Heidelberg and the Instituto de Astrofísica de Andalucía (CSIC). Based on observations made with the Italian Telescopio Nazionale Galileo

  8. Predicting diabetes mellitus using SMOTE and ensemble machine learning approach: The Henry Ford ExercIse Testing (FIT) project.

    Science.gov (United States)

    Alghamdi, Manal; Al-Mallah, Mouaz; Keteyian, Steven; Brawner, Clinton; Ehrman, Jonathan; Sakr, Sherif

    2017-01-01

    Machine learning is becoming a popular and important approach in the field of medical research. In this study, we investigate the relative performance of various machine learning methods such as Decision Tree, Naïve Bayes, Logistic Regression, Logistic Model Tree and Random Forests for predicting incident diabetes using medical records of cardiorespiratory fitness. In addition, we apply different techniques to uncover potential predictors of diabetes. This FIT project study used data of 32,555 patients who are free of any known coronary artery disease or heart failure who underwent clinician-referred exercise treadmill stress testing at Henry Ford Health Systems between 1991 and 2009 and had a complete 5-year follow-up. At the completion of the fifth year, 5,099 of those patients have developed diabetes. The dataset contained 62 attributes classified into four categories: demographic characteristics, disease history, medication use history, and stress test vital signs. We developed an Ensembling-based predictive model using 13 attributes that were selected based on their clinical importance, Multiple Linear Regression, and Information Gain Ranking methods. The negative effect of the imbalance class of the constructed model was handled by Synthetic Minority Oversampling Technique (SMOTE). The overall performance of the predictive model classifier was improved by the Ensemble machine learning approach using the Vote method with three Decision Trees (Naïve Bayes Tree, Random Forest, and Logistic Model Tree) and achieved high accuracy of prediction (AUC = 0.92). The study shows the potential of ensembling and SMOTE approaches for predicting incident diabetes using cardiorespiratory fitness data.

  9. In-cloud multiphase behaviour of acetone in the troposphere: gas uptake, Henry's law equilibrium and aqueous phase photooxidation.

    Science.gov (United States)

    Poulain, Laurent; Katrib, Yasmine; Isikli, Estelle; Liu, Yao; Wortham, Henri; Mirabel, Philippe; Le Calvé, Stéphane; Monod, Anne

    2010-09-01

    Acetone is ubiquitous in the troposphere. Several papers have focused in the past on its gas phase reactivity and its impact on tropospheric chemistry. However, acetone is also present in atmospheric water droplets where its behaviour is still relatively unknown. In this work, we present its gas/aqueous phase transfer and its aqueous phase photooxidation. The uptake coefficient of acetone on water droplets was measured between 268 and 281K (γ=0.7 x 10(-2)-1.4 x 10(-2)), using the droplet train technique coupled to a mass spectrometer. The mass accommodation coefficient α (derived from γ) was found in the range (1.0-3.0±0.25) x 10(-2). Henry's law constant of acetone was directly measured between 283 and 298K using a dynamic equilibrium system (H((298K))=(29±5)Matm(-1)), with the Van't Hoff expression lnH(T)=(5100±1100)/T-(13.4±3.9). A recommended value of H was suggested according to comparison with literature. The OH-oxidation of acetone in the aqueous phase was carried out at 298K, under two different pH conditions: at pH=2, and under unbuffered conditions. In both cases, the formation of methylglyoxal, formaldehyde, hydroxyacetone, acetic acid/acetate and formic acid/formate was observed. The formation of small amounts of four hydroperoxides was also detected, and one of them was identified as peroxyacetic acid. A drastic effect of pH was observed on the yields of formaldehyde, one hydroperoxide, and, (to a lesser extent) acetic acid/acetate. Based on the experimental observations, a chemical mechanism of OH-oxidation of acetone in the aqueous phase was proposed and discussed. Atmospheric implications of these findings were finally discussed. Copyright © 2010 Elsevier Ltd. All rights reserved.

  10. Predicting diabetes mellitus using SMOTE and ensemble machine learning approach: The Henry Ford ExercIse Testing (FIT project.

    Directory of Open Access Journals (Sweden)

    Manal Alghamdi

    Full Text Available Machine learning is becoming a popular and important approach in the field of medical research. In this study, we investigate the relative performance of various machine learning methods such as Decision Tree, Naïve Bayes, Logistic Regression, Logistic Model Tree and Random Forests for predicting incident diabetes using medical records of cardiorespiratory fitness. In addition, we apply different techniques to uncover potential predictors of diabetes. This FIT project study used data of 32,555 patients who are free of any known coronary artery disease or heart failure who underwent clinician-referred exercise treadmill stress testing at Henry Ford Health Systems between 1991 and 2009 and had a complete 5-year follow-up. At the completion of the fifth year, 5,099 of those patients have developed diabetes. The dataset contained 62 attributes classified into four categories: demographic characteristics, disease history, medication use history, and stress test vital signs. We developed an Ensembling-based predictive model using 13 attributes that were selected based on their clinical importance, Multiple Linear Regression, and Information Gain Ranking methods. The negative effect of the imbalance class of the constructed model was handled by Synthetic Minority Oversampling Technique (SMOTE. The overall performance of the predictive model classifier was improved by the Ensemble machine learning approach using the Vote method with three Decision Trees (Naïve Bayes Tree, Random Forest, and Logistic Model Tree and achieved high accuracy of prediction (AUC = 0.92. The study shows the potential of ensembling and SMOTE approaches for predicting incident diabetes using cardiorespiratory fitness data.

  11. Temperature dependencies of Henry's law constants and octanol/water partition coefficients for key plant volatile monoterpenoids.

    Science.gov (United States)

    Copolovici, Lucian O; Niinemets, Ulo

    2005-12-01

    To model the emission dynamics and changes in fractional composition of monoterpenoids from plant leaves, temperature dependencies of equilibrium coefficients must be known. Henry's law constants (H(pc), Pa m3 mol(-1) and octanol/water partition coefficients (K(OW), mol mol(-1)) were determined for 10 important plant monoterpenes at physiological temperature ranges (25-50 degrees C for H(pc) and 20-50 degrees C for K(OW)). A standard EPICS procedure was established to determine H(pc) and a shake flask method was used for the measurements of K(OW). The enthalpy of volatilization (deltaH(vol)) varied from 18.0 to 44.3 kJ mol(-1) among the monoterpenes, corresponding to a range of temperature-dependent increase in H(pc) between 1.3- and 1.8-fold per 10 degrees C rise in temperature. The enthalpy of water-octanol phase change varied from -11.0 to -23.8 kJ mol(-1), corresponding to a decrease of K(OW) between 1.15- and 1.32-fold per 10 degrees C increase in temperature. Correlations among physico-chemical characteristics of a wide range of monoterpenes were analyzed to seek the ways of derivation of H(pc) and K(OW) values from other monoterpene physico-chemical characteristics. H(pc) was strongly correlated with monoterpene saturated vapor pressure (P(v)), and for lipophilic monoterpenes, deltaH(vol) scaled positively with the enthalpy of vaporization that characterizes the temperature dependence of P(v) Thus, P(v) versus temperature relations may be employed to derive the temperature relations of H(pc) for these monoterpenes. These data collectively indicate that monoterpene differences in H(pc) and K(OW) temperature relations can importantly modify monoterpene emissions from and deposition on plant leaves.

  12. A Generalized Semi-Analytical Solution for the Dispersive Henry Problem: Effect of Stratification and Anisotropy on Seawater Intrusion

    Directory of Open Access Journals (Sweden)

    Marwan Fahs

    2018-02-01

    Full Text Available The Henry problem (HP continues to play a useful role in theoretical and practical studies related to seawater intrusion (SWI into coastal aquifers. The popularity of this problem is attributed to its simplicity and precision to the existence of semi-analytical (SA solutions. The first SA solution has been developed for a high uniform diffusion coefficient. Several further studies have contributed more realistic solutions with lower diffusion coefficients or velocity-dependent dispersion. All the existing SA solutions are limited to homogenous and isotropic domains. This work attempts to improve the realism of the SA solution of the dispersive HP by extending it to heterogeneous and anisotropic coastal aquifers. The solution is obtained using the Fourier series method. A special hydraulic conductivity–depth model describing stratified heterogeneity is used for mathematical convenience. An efficient technique is developed to solve the flow and transport equations in the spectral space. With this technique, we show that the HP can be solved in the spectral space with the salt concentration as primary unknown. Several examples are generated, and the SA solutions are compared against an in-house finite element code. The results provide high-quality data assessed by quantitative indicators that can be effectively used for code verification in realistic configurations of heterogeneity and anisotropy. The SA solution is used to explain contradictory results stated in the previous works about the effect of anisotropy on the saltwater wedge. It is also used to investigate the combined influence of stratification and anisotropy on relevant metrics characterizing SWI. At a constant gravity number, anisotropy leads to landward migration of the saltwater wedge, more intense saltwater flux, a wider mixing zone and shallower groundwater discharge zone to the sea. The influence of stratified heterogeneity is more pronounced in highly anisotropic aquifers. The

  13. Metabolic engineering of Pediococcus acidilactici BD16 for production of vanillin through ferulic acid catabolic pathway and process optimization using response surface methodology.

    Science.gov (United States)

    Kaur, Baljinder; Chakraborty, Debkumar; Kumar, Balvir

    2014-10-01

    Occurrence of feruloyl-CoA synthetase (fcs) and enoyl-CoA hydratase (ech) genes responsible for the bioconversion of ferulic acid to vanillin have been reported and characterized from Amycolatopsis sp., Streptomyces sp., and Pseudomonas sp. Attempts have been made to express these genes in Escherichia coli DH5α, E. coli JM109, and Pseudomonas fluorescens. However, none of the lactic acid bacteria strain having GRAS status was previously proposed for heterologous expression of fcs and ech genes for production of vanillin through biotechnological process. Present study reports heterologous expression of vanillin synthetic gene cassette bearing fcs and ech genes in a dairy isolate Pediococcus acidilactici BD16. After metabolic engineering, statistical optimization of process parameters that influence ferulic acid to vanillin biotransformation in the recombinant strain was carried out using central composite design of response surface methodology. After scale-up of the process, 3.14 mM vanillin was recovered from 1.08 mM ferulic acid per milligram of recombinant cell biomass within 20 min of biotransformation. From LCMS-ESI spectral analysis, a metabolic pathway of phenolic biotransformations was predicted in the recombinant P. acidilactici BD16 (fcs (+)/ech (+)).

  14. The BD Onclarity HPV assay on SurePath collected samples meets the International Guidelines for Human Papillomavirus Test Requirements for Cervical Screening

    DEFF Research Database (Denmark)

    Ejegod, Ditte; Bottari, Fabio; Pedersen, Helle

    2016-01-01

    This study describes a validation of the BD Onclarity HPV (Onclarity) assay using the international guidelines for HPV test requirements for cervical cancer screening of women 30 years and above using Danish SurePath screening samples. The clinical specificity (0.90, 95% CI: 0.88-0.91) and sensit......This study describes a validation of the BD Onclarity HPV (Onclarity) assay using the international guidelines for HPV test requirements for cervical cancer screening of women 30 years and above using Danish SurePath screening samples. The clinical specificity (0.90, 95% CI: 0.......88-0.91) and sensitivity (0.97, 95% CI: 0.87-1.0) of the Onclarity assay were shown to be non-inferior to the reference assay (specificity 0.90, 95% CI: 0.88-0.92, sensitivity 0.98, 95% CI: 0.91-1.0). The intra-laboratory reproducibility of Onclarity was 97% with a lower confidence bound of 96% (kappa value: 0...

  15. Modernization of Henry Borden hydroelectric power plant: The ELETROPAULO`s, The Electric Power Company of Sao Paulo State, experience in no.1 generator power improvement; Modernizacao da Usina Henry Borden (a experiencia da ELETROPAULO na repotenciacao do gerador nr. 1)

    Energy Technology Data Exchange (ETDEWEB)

    Delbone, Edval; Matos, Jose Alberto da S.; Grassi, Marco A; Oliveira, Robinson C; Sertori, Sergio R [Eletricidade de Sao Paulo SA, SP (Brazil); Duarte, F I; Pires, Nilo Ramos; Yamagushi, Luiz Massao [Asea Brown Boveri (ABB) (Brazil)

    1996-12-31

    The need for the substitution of several the generating equipment of Henry Borden hydroelectric power plant due to the end of their service life, in addition to the difficult economic situation and specific characteristics of the unit, leaded ELETROPAULO company to decide for the power improvement of some equipment. This work presents this experience giving special emphasis to the procedure adopted and results obtained 2 tabs.

  16. Etteheited räsivad pidu / Henri Reeder, Ly Rääsk, Heli Jürgenson ... [jt.] ; intervjueerinud Anneli Aasmäe

    Index Scriptorium Estoniae

    2009-01-01

    Küsimustele tänavusele üldlaulu- ja üldtantsupeole minekust ja peo repertuaari raskusest vastavad Aruküla noortekoori laulja Henri Reeder, Äksi segakoori dirigent Ly Rääsk, üldlaulupeo segakooride liigijuht Heli Jürgenson, Laulu- ja Tantsupeo SA muusikatoimetaja Ave Sopp, Laulu- ja Tantsupeo SA tantsutoimetaja Kadri Tiis , Lüganuse segakoori dirigent Priit-Andres Pärtna ja kolme tantsurühma juhendaja Vändrast Kädi Pärnoja

  17. The Paradox of a Gesture, Enlarged by the Distension of Time: Merleau-Ponty and Lacan on a Slow-Motion Picture of Henri Matisse Painting

    OpenAIRE

    Astrid Deuber-Mankowsky

    2017-01-01

    In his lecture series The Four Fundamental Concepts of Psychoanalysis (1964), Lacan refers to a “delightful example” that Merleau-Ponty gives in his Book Signes (1960). Lacan describes it as a “strange slow-motion film in which one sees Matisse painting.” This is a scene from the documentary entitled A Great French Painter, Henri Matisse, by director François Campaux, a 16mm black and white film shot in 1946. Merleau-Ponty points, as Lacan puts it, to “the paradox of that gesture which, enlar...

  18. Le Visage de la Victoire di Henry De Groux: la riscoperta di un’opera antimilitarista del tempo della Prima guerra mondiale

    Directory of Open Access Journals (Sweden)

    Carol Morganti

    2014-03-01

    Full Text Available Il presente intervento è dedicato a un’importante raccolta di incisioni, oggi riscoperta: Le Visage de la Victoire, eseguita dall’artista belga Henry De Groux. Costituita da oltre 40 incisioni (acqueforti e vernici molli, è stata realizzata nel corso della Prima Guerra Mondiale al fine di denunciare l’inutile massacro in corso. Si tratta di opere di ispirazione visionaria, che rivelano significati universali, mettendo il maestro belga in rapporto di affinità con artisti quali Goya e Otto Dix.

  19. O BOM FILHO À CASA TORNA: FORMAÇÃO HUMANISTA EUROPEIA E SENTIMENTO PÁTRIO EM JOAQUIM NABUCO E HENRY JAMES

    OpenAIRE

    Mello, Luiza Larangeira da Silva

    2013-01-01

    Resumo Este artigo propõe uma análise comparativa entre textos de caráter autobiográfico do intelectual e político brasileiro Joaquim Nabuco e do escritor norte-americano Henry James, nos quais eles modelam suas subjetividades e confrontam-se com alguns dos problemas que mobilizaram boa parte dos intelectuais, na virada do século XIX para o XX. Tanto Minha formação (1900), de Nabuco, quanto The American scene (1907), de James, representam o sentimento a que Evaldo Cabral de Mello chama "o dil...

  20. Henri FAYOL, 100 ans et pas une ride L’apport de l’œuvre de Fayol dans le monde moderne

    OpenAIRE

    Brodhag, Christian

    2016-01-01

    International audience; Demain se tiendra à l'Ecole un colloque scientifique sur Henri FAYOL, il permettra à des chercheurs d'horizons variés de porter des regards croisés sur l'oeuvre de notre glorieux ancien. Certains sont déjà présents ce soir, et je les salue. En posant la question de la pertinence de l'actualité de l'oeuvre de FAYOL, je ne me départirai pas de la rigueur qui sied au scientifique, mais je ne m'accorderai une licence plus politique. En effet cette dimension de l'oeuvre de ...