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Sample records for fully constrained formulation

  1. Gravitational waves in Fully Constrained Formulation in a dynamical spacetime with matter content

    Energy Technology Data Exchange (ETDEWEB)

    Cordero-Carrion, Isabel; Cerda-Duran, Pablo [Max-Planck-Institut fuer Astrophysik, Karl-Schwarzschild-Str. 1, D-85741, Garching (Germany); Ibanez, Jose MarIa, E-mail: chabela@mpa-garching.mpg.de, E-mail: cerda@mpa-garching.mpg.de, E-mail: jose.m.ibanez@uv.es [Departamento de AstronomIa y Astrofisica, Universidad de Valencia, C/ Dr. Moliner 50, E-46100 Burjassot, Valencia (Spain)

    2011-09-22

    We analyze numerically the behaviour of the hyperbolic sector of the Fully Constrained Formulation (FCF) (Bonazzola et al. 2004). The numerical experiments allow us to be confident in the performances of the upgraded version of the CoCoNuT code (Dimmelmeier et al. 2005) by replacing the Conformally Flat Condition (CFC), an approximation of Einstein equations, by FCF. First gravitational waves in FCF in a dynamical spacetime with matter content will be shown.

  2. Classification of Hyperspectral Images Using Kernel Fully Constrained Least Squares

    Directory of Open Access Journals (Sweden)

    Jianjun Liu

    2017-11-01

    Full Text Available As a widely used classifier, sparse representation classification (SRC has shown its good performance for hyperspectral image classification. Recent works have highlighted that it is the collaborative representation mechanism under SRC that makes SRC a highly effective technique for classification purposes. If the dimensionality and the discrimination capacity of a test pixel is high, other norms (e.g., ℓ 2 -norm can be used to regularize the coding coefficients, except for the sparsity ℓ 1 -norm. In this paper, we show that in the kernel space the nonnegative constraint can also play the same role, and thus suggest the investigation of kernel fully constrained least squares (KFCLS for hyperspectral image classification. Furthermore, in order to improve the classification performance of KFCLS by incorporating spatial-spectral information, we investigate two kinds of spatial-spectral methods using two regularization strategies: (1 the coefficient-level regularization strategy, and (2 the class-level regularization strategy. Experimental results conducted on four real hyperspectral images demonstrate the effectiveness of the proposed KFCLS, and show which way to incorporate spatial-spectral information efficiently in the regularization framework.

  3. Excision technique in constrained formulations of Einstein equations: collapse scenario

    International Nuclear Information System (INIS)

    Cordero-Carrión, I; Vasset, N; Novak, J; Jaramillo, J L

    2015-01-01

    We present a new excision technique used in constrained formulations of Einstein equations to deal with black hole in numerical simulations. We show the applicability of this scheme in several scenarios. In particular, we present the dynamical evolution of the collapse of a neutron star to a black hole, using the CoCoNuT code and this excision technique. (paper)

  4. Towards a Scalable Fully-Implicit Fully-coupled Resistive MHD Formulation with Stabilized FE Methods

    Energy Technology Data Exchange (ETDEWEB)

    Shadid, J N; Pawlowski, R P; Banks, J W; Chacon, L; Lin, P T; Tuminaro, R S

    2009-06-03

    This paper presents an initial study that is intended to explore the development of a scalable fully-implicit stabilized unstructured finite element (FE) capability for low-Mach-number resistive MHD. The discussion considers the development of the stabilized FE formulation and the underlying fully-coupled preconditioned Newton-Krylov nonlinear iterative solver. To enable robust, scalable and efficient solution of the large-scale sparse linear systems generated by the Newton linearization, fully-coupled algebraic multilevel preconditioners are employed. Verification results demonstrate the expected order-of-acuracy for the stabilized FE discretization of a 2D vector potential form for the steady and transient solution of the resistive MHD system. In addition, this study puts forth a set of challenging prototype problems that include the solution of an MHD Faraday conduction pump, a hydromagnetic Rayleigh-Bernard linear stability calculation, and a magnetic island coalescence problem. Initial results that explore the scaling of the solution methods are presented on up to 4096 processors for problems with up to 64M unknowns on a CrayXT3/4. Additionally, a large-scale proof-of-capability calculation for 1 billion unknowns for the MHD Faraday pump problem on 24,000 cores is presented.

  5. The impact of a fully idealised high speed train into a constrained fuel transport flask

    International Nuclear Information System (INIS)

    Dowler, H.J.

    1985-05-01

    The outcome of an accident involving a high speed train, travelling at 125 mph and impacting a stationary irradiated fuel transport flask is investigated. The case considered is that of a fully constrained flask and the power cars and carriages are fully idealised. A representation of the impact and an estimate of the resulting force-time curve experienced by the fuel flask are given. It is found that the peak force is not increased by the addition of coaches, but the time duration of the impact is lengthened. (author)

  6. Conditions for the Solvability of the Linear Programming Formulation for Constrained Discounted Markov Decision Processes

    Energy Technology Data Exchange (ETDEWEB)

    Dufour, F., E-mail: dufour@math.u-bordeaux1.fr [Institut de Mathématiques de Bordeaux, INRIA Bordeaux Sud Ouest, Team: CQFD, and IMB (France); Prieto-Rumeau, T., E-mail: tprieto@ccia.uned.es [UNED, Department of Statistics and Operations Research (Spain)

    2016-08-15

    We consider a discrete-time constrained discounted Markov decision process (MDP) with Borel state and action spaces, compact action sets, and lower semi-continuous cost functions. We introduce a set of hypotheses related to a positive weight function which allow us to consider cost functions that might not be bounded below by a constant, and which imply the solvability of the linear programming formulation of the constrained MDP. In particular, we establish the existence of a constrained optimal stationary policy. Our results are illustrated with an application to a fishery management problem.

  7. Fully constrained Majorana neutrino mass matrices using Σ(72 x 3)

    Energy Technology Data Exchange (ETDEWEB)

    Krishnan, R.; Harrison, P.F. [Warwick Univ., Coventry (United Kingdom); Scott, W.G. [Rutherford Appleton Laboratory, Chilton, Didcot (United Kingdom)

    2018-01-15

    In 2002, two neutrino mixing ansatze having trimaximally mixed middle (ν{sub 2}) columns, namely tri-chi-maximal mixing (TχM) and tri-phi-maximal mixing (TφM), were proposed. In 2012, it was shown that TχM with χ = ± (π)/(16) as well as TφM with φ = ± (π)/(16) leads to the solution, sin{sup 2} θ{sub 13} = (2)/(3) sin{sup 2} (π)/(16), consistent with the latest measurements of the reactor mixing angle, θ{sub 13}. To obtain TχM{sub (χ=±(π)/(16))} and TφM{sub (φ=±(π)/(16))}, the type I see-saw framework with fully constrained Majorana neutrino mass matrices was utilised. These mass matrices also resulted in the neutrino mass ratios, m{sub 1}: m{sub 2}: m{sub 3} = ((2+√2))/(1+√(2(2+√2))): 1: ((2+√2))/(-1+√(2(2+√2))). In this paper we construct a flavour model based on the discrete group Σ(72 x 3) and obtain the aforementioned results. A Majorana neutrino mass matrix (a symmetric 3 x 3 matrix with six complex degrees of freedom) is conveniently mapped into a flavon field transforming as the complex six-dimensional representation of Σ(72 x 3). Specific vacuum alignments of the flavons are used to arrive at the desired mass matrices. (orig.)

  8. A constrained multinomial Probit route choice model in the metro network: Formulation, estimation and application

    Science.gov (United States)

    Zhang, Yongsheng; Wei, Heng; Zheng, Kangning

    2017-01-01

    Considering that metro network expansion brings us with more alternative routes, it is attractive to integrate the impacts of routes set and the interdependency among alternative routes on route choice probability into route choice modeling. Therefore, the formulation, estimation and application of a constrained multinomial probit (CMNP) route choice model in the metro network are carried out in this paper. The utility function is formulated as three components: the compensatory component is a function of influencing factors; the non-compensatory component measures the impacts of routes set on utility; following a multivariate normal distribution, the covariance of error component is structured into three parts, representing the correlation among routes, the transfer variance of route, and the unobserved variance respectively. Considering multidimensional integrals of the multivariate normal probability density function, the CMNP model is rewritten as Hierarchical Bayes formula and M-H sampling algorithm based Monte Carlo Markov Chain approach is constructed to estimate all parameters. Based on Guangzhou Metro data, reliable estimation results are gained. Furthermore, the proposed CMNP model also shows a good forecasting performance for the route choice probabilities calculation and a good application performance for transfer flow volume prediction. PMID:28591188

  9. A fully implicit Newton-Krylov-Schwarz method for tokamak magnetohydrodynamics: Jacobian construction and preconditioner formulation

    KAUST Repository

    Reynolds, Daniel R.

    2012-01-01

    Single-fluid resistive magnetohydrodynamics (MHD) is a fluid description of fusion plasmas which is often used to investigate macroscopic instabilities in tokamaks. In MHD modeling of tokamaks, it is often desirable to compute MHD phenomena to resistive time scales or a combination of resistive-Alfvén time scales, which can render explicit time stepping schemes computationally expensive. We present recent advancements in the development of preconditioners for fully nonlinearly implicit simulations of single-fluid resistive tokamak MHD. Our work focuses on simulations using a structured mesh mapped into a toroidal geometry with a shaped poloidal cross-section, and a finite-volume spatial discretization of the partial differential equation model. We discretize the temporal dimension using a fully implicit or the backwards differentiation formula method, and solve the resulting nonlinear algebraic system using a standard inexact Newton-Krylov approach, provided by the sundials library. The focus of this paper is on the construction and performance of various preconditioning approaches for accelerating the convergence of the iterative solver algorithms. Effective preconditioners require information about the Jacobian entries; however, analytical formulae for these Jacobian entries may be prohibitive to derive/implement without error. We therefore compute these entries using automatic differentiation with OpenAD. We then investigate a variety of preconditioning formulations inspired by standard solution approaches in modern MHD codes, in order to investigate their utility in a preconditioning context. We first describe the code modifications necessary for the use of the OpenAD tool and sundials solver library. We conclude with numerical results for each of our preconditioning approaches in the context of pellet-injection fueling of tokamak plasmas. Of these, our optimal approach results in a speedup of a factor of 3 compared with non-preconditioned implicit tests, with

  10. A constrained maximization formulation to analyze deformation of fiber reinforced elastomeric actuators

    Science.gov (United States)

    Singh, Gaurav; Krishnan, Girish

    2017-06-01

    Fiber reinforced elastomeric enclosures (FREEs) are soft and smart pneumatic actuators that deform in a predetermined fashion upon inflation. This paper analyzes the deformation behavior of FREEs by formulating a simple calculus of variations problem that involves constrained maximization of the enclosed volume. The model accurately captures the deformed shape for FREEs with any general fiber angle orientation, and its relation with actuation pressure, material properties and applied load. First, the accuracy of the model is verified with existing literature and experiments for the popular McKibben pneumatic artificial muscle actuator with two equal and opposite families of helically wrapped fibers. Then, the model is used to predict and experimentally validate the deformation behavior of novel rotating-contracting FREEs, for which no prior literature exist. The generality of the model enables conceptualization of novel FREEs whose fiber orientations vary arbitrarily along the geometry. Furthermore, the model is deemed to be useful in the design synthesis of fiber reinforced elastomeric actuators for general axisymmetric desired motion and output force requirement.

  11. Dynamical computation of constrained flexible systems using a modal Udwadia-Kalaba formulation: Application to musical instruments.

    Science.gov (United States)

    Antunes, J; Debut, V

    2017-02-01

    Most musical instruments consist of dynamical subsystems connected at a number of constraining points through which energy flows. For physical sound synthesis, one important difficulty deals with enforcing these coupling constraints. While standard techniques include the use of Lagrange multipliers or penalty methods, in this paper, a different approach is explored, the Udwadia-Kalaba (U-K) formulation, which is rooted on analytical dynamics but avoids the use of Lagrange multipliers. This general and elegant formulation has been nearly exclusively used for conceptual systems of discrete masses or articulated rigid bodies, namely, in robotics. However its natural extension to deal with continuous flexible systems is surprisingly absent from the literature. Here, such a modeling strategy is developed and the potential of combining the U-K equation for constrained systems with the modal description is shown, in particular, to simulate musical instruments. Objectives are twofold: (1) Develop the U-K equation for constrained flexible systems with subsystems modelled through unconstrained modes; and (2) apply this framework to compute string/body coupled dynamics. This example complements previous work [Debut, Antunes, Marques, and Carvalho, Appl. Acoust. 108, 3-18 (2016)] on guitar modeling using penalty methods. Simulations show that the proposed technique provides similar results with a significant improvement in computational efficiency.

  12. Robust and Reliable Portfolio Optimization Formulation of a Chance Constrained Problem

    Directory of Open Access Journals (Sweden)

    Sengupta Raghu Nandan

    2017-02-01

    Full Text Available We solve a linear chance constrained portfolio optimization problem using Robust Optimization (RO method wherein financial script/asset loss return distributions are considered as extreme valued. The objective function is a convex combination of portfolio’s CVaR and expected value of loss return, subject to a set of randomly perturbed chance constraints with specified probability values. The robust deterministic counterpart of the model takes the form of Second Order Cone Programming (SOCP problem. Results from extensive simulation runs show the efficacy of our proposed models, as it helps the investor to (i utilize extensive simulation studies to draw insights into the effect of randomness in portfolio decision making process, (ii incorporate different risk appetite scenarios to find the optimal solutions for the financial portfolio allocation problem and (iii compare the risk and return profiles of the investments made in both deterministic as well as in uncertain and highly volatile financial markets.

  13. Timing-Constrained FPGA Placement: A Force-Directed Formulation and Its Performance Evaluation

    Directory of Open Access Journals (Sweden)

    Srilata Raman

    1996-01-01

    Full Text Available In this paper we present a simple but efficient timing-driven placement algorithm for FPGAs. The algorithm computes forces acting on a logic block in the FPGA to determine its relative location with respect to other blocks. The forces depend on the criticality of nets shared between the two blocks. Unlike other net-based approaches, timing constraints are incorporated directly into the force equations to guide the placement. Slot assignment is then used to move the blocks into valid slot locations on the FPGA chip. The assignment algorithm also makes use of the delay information of nets so that the final placement is able to meet the timing criteria specified for the circuit. The novelty of the approach lies in the formulation of the force equations and the manner in which weights of the nets are dynamically altered to influence the placement. Experiments conducted on industrial test circuits and MCNC circuits give very promising results and indicate that the algorithm succeeds in significantly reducing the maximum delay in the circuit. In addition, routability is not adversely affected and running time is low.

  14. Characterization of new functionalized calcium carbonate-polycaprolactone composite material for application in geometry-constrained drug release formulation development.

    Science.gov (United States)

    Wagner-Hattler, Leonie; Schoelkopf, Joachim; Huwyler, Jörg; Puchkov, Maxim

    2017-10-01

    A new mineral-polymer composite (FCC-PCL) performance was assessed to produce complex geometries to aid in development of controlled release tablet formulations. The mechanical characteristics of a developed material such as compactibility, compressibility and elastoplastic deformation were measured. The results and comparative analysis versus other common excipients suggest efficient formation of a complex, stable and impermeable geometries for constrained drug release modifications under compression. The performance of the proposed composite material has been tested by compacting it into a geometrically altered tablet (Tablet-In-Cup, TIC) and the drug release was compared to commercially available product. The TIC device exhibited a uniform surface, showed high physical stability, and showed absence of friability. FCC-PCL composite had good binding properties and good compactibility. It was possible to reveal an enhanced plasticity characteristic of a new material which was not present in the individual components. The presented FCC-PCL composite mixture has the potential to become a successful tool to formulate controlled-release dosage solid forms.

  15. A multi-fidelity analysis selection method using a constrained discrete optimization formulation

    Science.gov (United States)

    Stults, Ian C.

    The purpose of this research is to develop a method for selecting the fidelity of contributing analyses in computer simulations. Model uncertainty is a significant component of result validity, yet it is neglected in most conceptual design studies. When it is considered, it is done so in only a limited fashion, and therefore brings the validity of selections made based on these results into question. Neglecting model uncertainty can potentially cause costly redesigns of concepts later in the design process or can even cause program cancellation. Rather than neglecting it, if one were to instead not only realize the model uncertainty in tools being used but also use this information to select the tools for a contributing analysis, studies could be conducted more efficiently and trust in results could be quantified. Methods for performing this are generally not rigorous or traceable, and in many cases the improvement and additional time spent performing enhanced calculations are washed out by less accurate calculations performed downstream. The intent of this research is to resolve this issue by providing a method which will minimize the amount of time spent conducting computer simulations while meeting accuracy and concept resolution requirements for results. In many conceptual design programs, only limited data is available for quantifying model uncertainty. Because of this data sparsity, traditional probabilistic means for quantifying uncertainty should be reconsidered. This research proposes to instead quantify model uncertainty using an evidence theory formulation (also referred to as Dempster-Shafer theory) in lieu of the traditional probabilistic approach. Specific weaknesses in using evidence theory for quantifying model uncertainty are identified and addressed for the purposes of the Fidelity Selection Problem. A series of experiments was conducted to address these weaknesses using n-dimensional optimization test functions. These experiments found that model

  16. The Regularized Fast Hartley Transform Optimal Formulation of Real-Data Fast Fourier Transform for Silicon-Based Implementation in Resource-Constrained Environments

    CERN Document Server

    Jones, Keith

    2010-01-01

    The Regularized Fast Hartley Transform provides the reader with the tools necessary to both understand the proposed new formulation and to implement simple design variations that offer clear implementational advantages, both practical and theoretical, over more conventional complex-data solutions to the problem. The highly-parallel formulation described is shown to lead to scalable and device-independent solutions to the latency-constrained version of the problem which are able to optimize the use of the available silicon resources, and thus to maximize the achievable computational density, th

  17. Thermal conductivity of fully dense unirradiated UO2: A new formulation from experimental results between 100 deg. C and 2500 deg. C, and associated fundamental properties

    International Nuclear Information System (INIS)

    Delette, G.; Charles, M.

    1997-01-01

    The various contributions to the thermal conductivity of UO 2 are first reviewed: contribution from phonons is preponderant up to 1600 deg. C; radiative contribution is negligible in the case of a polycrystalline sample, and is unable to account for the increase in conductivity observed above 1600 deg. C; electronic contribution, which seems patently to be responsible for this increase, is efficient from 1400 deg. C (electron-hole pairs treated as small polarons). Given the lack of decisive arguments on their actual efficiency, it was decided that, for temperatures above 2400 deg. C, neither a possible decrease in the electronic contribution due to vacancies, nor an additional possible contribution from Frenkel pairs would be described. We do not go therefore beyond the above-mentioned electronic contribution. In the light of these considerations, the law established by CEA for the thermal conductivity of unirradiated UO 2 , on the basis of a homogeneous set of measurements between 100 deg. C and 2500 deg. C, has been revised. A least-square method applied to the above measurements was used to derive simultaneously the four adjustable constants of the law which is henceforth proposed: λ = 1/A + BT+C/T 2 exp(-W/kT). The values of A, B, C, and W obtained, have the advantage of giving a better account of the high temperature results compared to the Martin recommendations (which has, by the way, the same physical form as above). Furthermore, this new law allows an extrapolation towards the melting point which is better founded than the earlier CEA law, while still respecting the value of the integrated thermal conductivity up to melting. Finally, various burnup effects (impurities, stoichiometry, etc.) can be formulated in physical terms. Moreover, the values of various fundamental properties connected with the derived constants have been determined: Debye temperature, Grueneisen parameter, Mott-Hubbard energy, electrical conductivity. These values are discussed and

  18. Thermal conductivity of fully dense unirradiated UO{sub 2}: A new formulation from experimental results between 100 deg. C and 2500 deg. C, and associated fundamental properties

    Energy Technology Data Exchange (ETDEWEB)

    Delette, G; Charles, M [Commissariat a l` Energie Atomique, Grenoble (France)

    1997-08-01

    The various contributions to the thermal conductivity of UO{sub 2} are first reviewed: contribution from phonons is preponderant up to 1600 deg. C; radiative contribution is negligible in the case of a polycrystalline sample, and is unable to account for the increase in conductivity observed above 1600 deg. C; electronic contribution, which seems patently to be responsible for this increase, is efficient from 1400 deg. C (electron-hole pairs treated as small polarons). Given the lack of decisive arguments on their actual efficiency, it was decided that, for temperatures above 2400 deg. C, neither a possible decrease in the electronic contribution due to vacancies, nor an additional possible contribution from Frenkel pairs would be described. We do not go therefore beyond the above-mentioned electronic contribution. In the light of these considerations, the law established by CEA for the thermal conductivity of unirradiated UO{sub 2}, on the basis of a homogeneous set of measurements between 100 deg. C and 2500 deg. C, has been revised. A least-square method applied to the above measurements was used to derive simultaneously the four adjustable constants of the law which is henceforth proposed: {lambda} = 1/A + BT+C/T{sup 2}exp(-W/kT). The values of A, B, C, and W obtained, have the advantage of giving a better account of the high temperature results compared to the Martin recommendations (which has, by the way, the same physical form as above). Furthermore, this new law allows an extrapolation towards the melting point which is better founded than the earlier CEA law, while still respecting the value of the integrated thermal conductivity up to melting. Finally, various burnup effects (impurities, stoichiometry, etc.) can be formulated in physical terms. Moreover, the values of various fundamental properties connected with the derived constants have been determined: Debye temperature, Grueneisen parameter, Mott-Hubbard energy, electrical conductivity. These values

  19. A nodally condensed SUPG formulation for free-surface computation of steady-state flows constrained by unilateral contact - Application to rolling

    Science.gov (United States)

    Arora, Shitij; Fourment, Lionel

    2018-05-01

    In the context of the simulation of industrial hot forming processes, the resultant time-dependent thermo-mechanical multi-field problem (v →,p ,σ ,ɛ ) can be sped up by 10-50 times using the steady-state methods while compared to the conventional incremental methods. Though the steady-state techniques have been used in the past, but only on simple configurations and with structured meshes, and the modern-days problems are in the framework of complex configurations, unstructured meshes and parallel computing. These methods remove time dependency from the equations, but introduce an additional unknown into the problem: the steady-state shape. This steady-state shape x → can be computed as a geometric correction t → on the domain X → by solving the weak form of the steady-state equation v →.n →(t →)=0 using a Streamline Upwind Petrov Galerkin (SUPG) formulation. There exists a strong coupling between the domain shape and the material flow, hence, a two-step fixed point iterative resolution algorithm was proposed that involves (1) the computation of flow field from the resolution of thermo-mechanical equations on a prescribed domain shape and (2) the computation of steady-state shape for an assumed velocity field. The contact equations are introduced in the penalty form both during the flow computation as well as during the free-surface correction. The fact that the contact description is inhomogeneous, i.e., it is defined in the nodal form in the former, and in the weighted residual form in the latter, is assumed to be critical to the convergence of certain problems. Thus, the notion of nodal collocation is invoked in the weak form of the surface correction equation to homogenize the contact coupling. The surface correction algorithm is tested on certain analytical test cases and the contact coupling is tested with some hot rolling problems.

  20. Constrained evolution in numerical relativity

    Science.gov (United States)

    Anderson, Matthew William

    The strongest potential source of gravitational radiation for current and future detectors is the merger of binary black holes. Full numerical simulation of such mergers can provide realistic signal predictions and enhance the probability of detection. Numerical simulation of the Einstein equations, however, is fraught with difficulty. Stability even in static test cases of single black holes has proven elusive. Common to unstable simulations is the growth of constraint violations. This work examines the effect of controlling the growth of constraint violations by solving the constraints periodically during a simulation, an approach called constrained evolution. The effects of constrained evolution are contrasted with the results of unconstrained evolution, evolution where the constraints are not solved during the course of a simulation. Two different formulations of the Einstein equations are examined: the standard ADM formulation and the generalized Frittelli-Reula formulation. In most cases constrained evolution vastly improves the stability of a simulation at minimal computational cost when compared with unconstrained evolution. However, in the more demanding test cases examined, constrained evolution fails to produce simulations with long-term stability in spite of producing improvements in simulation lifetime when compared with unconstrained evolution. Constrained evolution is also examined in conjunction with a wide variety of promising numerical techniques, including mesh refinement and overlapping Cartesian and spherical computational grids. Constrained evolution in boosted black hole spacetimes is investigated using overlapping grids. Constrained evolution proves to be central to the host of innovations required in carrying out such intensive simulations.

  1. A technique for determining the optimum mix of logistics service providers of a make-to-order supply chain by formulating and solving a constrained nonlinear cost optimization problem

    Directory of Open Access Journals (Sweden)

    Mrityunjoy Roy

    2013-04-01

    Full Text Available In this paper, a technique has been developed to determine the optimum mix of logistic service providers of a make-to-order (MTO supply chain. A serial MTO supply chain with different stages/ processes has been considered. For each stage different logistic service providers with different mean processing lead times, but same lead time variances are available. A realistic assumption that for each stage, the logistic service provider who charges more for his service consumes less processing lead time and vice-versa has been made in our study. Thus for each stage, for each service provider, a combination of cost and mean processing lead time is available. Using these combinations, for each stage, a polynomial curve, expressing cost of that stage as a function of mean processing lead time is fit. Cumulating all such expressions of cost for the different stages along with incorporation of suitable constraints arising out of timely delivery, results in the formulation of a constrained nonlinear cost optimization problem. On solving the problem using mathematica, optimum processing lead time for each stage is obtained. Using these optimum processing lead times and by employing a simple technique the optimum logistic service provider mix of the supply chain along with the corresponding total cost of processing is determined. Finally to examine the effect of changes in different parameters on the optimum total processing cost of the supply chain, sensitivity analysis has been carried out graphically.

  2. Constrained consequence

    CSIR Research Space (South Africa)

    Britz, K

    2011-09-01

    Full Text Available their basic properties and relationship. In Section 3 we present a modal instance of these constructions which also illustrates with an example how to reason abductively with constrained entailment in a causal or action oriented context. In Section 4 we... of models with the former approach, whereas in Section 3.3 we give an example illustrating ways in which C can be de ned with both. Here we employ the following versions of local consequence: De nition 3.4. Given a model M = hW;R;Vi and formulas...

  3. Mathematical Modeling of Constrained Hamiltonian Systems

    NARCIS (Netherlands)

    Schaft, A.J. van der; Maschke, B.M.

    1995-01-01

    Network modelling of unconstrained energy conserving physical systems leads to an intrinsic generalized Hamiltonian formulation of the dynamics. Constrained energy conserving physical systems are directly modelled as implicit Hamiltonian systems with regard to a generalized Dirac structure on the

  4. Dynamic Convex Duality in Constrained Utility Maximization

    OpenAIRE

    Li, Yusong; Zheng, Harry

    2016-01-01

    In this paper, we study a constrained utility maximization problem following the convex duality approach. After formulating the primal and dual problems, we construct the necessary and sufficient conditions for both the primal and dual problems in terms of FBSDEs plus additional conditions. Such formulation then allows us to explicitly characterize the primal optimal control as a function of the adjoint process coming from the dual FBSDEs in a dynamic fashion and vice versa. Moreover, we also...

  5. Fully exponentially correlated wavefunctions for small atoms

    Energy Technology Data Exchange (ETDEWEB)

    Harris, Frank E. [Department of Physics, University of Utah, Salt Lake City, UT 84112 and Quantum Theory Project, University of Florida, P.O. Box 118435, Gainesville, FL 32611 (United States)

    2015-01-22

    Fully exponentially correlated atomic wavefunctions are constructed from exponentials in all the interparticle coordinates, in contrast to correlated wavefunctions of the Hylleraas form, in which only the electron-nuclear distances occur exponentially, with electron-electron distances entering only as integer powers. The full exponential correlation causes many-configuration wavefunctions to converge with expansion length more rapidly than either orbital formulations or correlated wavefunctions of the Hylleraas type. The present contribution surveys the effectiveness of fully exponentially correlated functions for the three-body system (the He isoelectronic series) and reports their application to a four-body system (the Li atom)

  6. Evolutionary constrained optimization

    CERN Document Server

    Deb, Kalyanmoy

    2015-01-01

    This book makes available a self-contained collection of modern research addressing the general constrained optimization problems using evolutionary algorithms. Broadly the topics covered include constraint handling for single and multi-objective optimizations; penalty function based methodology; multi-objective based methodology; new constraint handling mechanism; hybrid methodology; scaling issues in constrained optimization; design of scalable test problems; parameter adaptation in constrained optimization; handling of integer, discrete and mix variables in addition to continuous variables; application of constraint handling techniques to real-world problems; and constrained optimization in dynamic environment. There is also a separate chapter on hybrid optimization, which is gaining lots of popularity nowadays due to its capability of bridging the gap between evolutionary and classical optimization. The material in the book is useful to researchers, novice, and experts alike. The book will also be useful...

  7. Constrained optimization via simulation models for new product innovation

    Science.gov (United States)

    Pujowidianto, Nugroho A.

    2017-11-01

    We consider the problem of constrained optimization where the decision makers aim to optimize the primary performance measure while constraining the secondary performance measures. This paper provides a brief overview of stochastically constrained optimization via discrete event simulation. Most review papers tend to be methodology-based. This review attempts to be problem-based as decision makers may have already decided on the problem formulation. We consider constrained optimization models as there are usually constraints on secondary performance measures as trade-off in new product development. It starts by laying out different possible methods and the reasons using constrained optimization via simulation models. It is then followed by the review of different simulation optimization approach to address constrained optimization depending on the number of decision variables, the type of constraints, and the risk preferences of the decision makers in handling uncertainties.

  8. Fully portable blood irradiator

    International Nuclear Information System (INIS)

    Hungate, F.P.; Riemath, W.F.; Bunnell, L.R.

    1980-01-01

    A fully portable blood irradiator was developed using the beta emitter thulium-170 as the radiation source and vitreous carbon as the body of the irradiator, matrix for isotope encapsulation, and blood interface material. These units were placed in exteriorized arteriovenous shunts in goats, sheep, and dogs and the effects on circulating lymphocytes and on skin allograft retention times measured. The present work extends these studies by establishing baseline data for skin graft rejection times in untreated animals

  9. Exploring Constrained Creative Communication

    DEFF Research Database (Denmark)

    Sørensen, Jannick Kirk

    2017-01-01

    Creative collaboration via online tools offers a less ‘media rich’ exchange of information between participants than face-to-face collaboration. The participants’ freedom to communicate is restricted in means of communication, and rectified in terms of possibilities offered in the interface. How do...... these constrains influence the creative process and the outcome? In order to isolate the communication problem from the interface- and technology problem, we examine via a design game the creative communication on an open-ended task in a highly constrained setting, a design game. Via an experiment the relation...... between communicative constrains and participants’ perception of dialogue and creativity is examined. Four batches of students preparing for forming semester project groups were conducted and documented. Students were asked to create an unspecified object without any exchange of communication except...

  10. Choosing health, constrained choices.

    Science.gov (United States)

    Chee Khoon Chan

    2009-12-01

    In parallel with the neo-liberal retrenchment of the welfarist state, an increasing emphasis on the responsibility of individuals in managing their own affairs and their well-being has been evident. In the health arena for instance, this was a major theme permeating the UK government's White Paper Choosing Health: Making Healthy Choices Easier (2004), which appealed to an ethos of autonomy and self-actualization through activity and consumption which merited esteem. As a counterpoint to this growing trend of informed responsibilization, constrained choices (constrained agency) provides a useful framework for a judicious balance and sense of proportion between an individual behavioural focus and a focus on societal, systemic, and structural determinants of health and well-being. Constrained choices is also a conceptual bridge between responsibilization and population health which could be further developed within an integrative biosocial perspective one might refer to as the social ecology of health and disease.

  11. Android Fully Loaded

    CERN Document Server

    Huddleston, Rob

    2012-01-01

    Fully loaded with the latest tricks and tips on your new Android! Android smartphones are so hot, they're soaring past iPhones on the sales charts. And the second edition of this muscular little book is equally impressive--it's packed with tips and tricks for getting the very most out of your latest-generation Android device. Start Facebooking and tweeting with your Android mobile, scan barcodes to get pricing and product reviews, download your favorite TV shows--the book is positively bursting with practical and fun how-tos. Topics run the gamut from using speech recognition, location-based m

  12. Constrained superfields in supergravity

    Energy Technology Data Exchange (ETDEWEB)

    Dall’Agata, Gianguido; Farakos, Fotis [Dipartimento di Fisica ed Astronomia “Galileo Galilei”, Università di Padova,Via Marzolo 8, 35131 Padova (Italy); INFN, Sezione di Padova,Via Marzolo 8, 35131 Padova (Italy)

    2016-02-16

    We analyze constrained superfields in supergravity. We investigate the consistency and solve all known constraints, presenting a new class that may have interesting applications in the construction of inflationary models. We provide the superspace Lagrangians for minimal supergravity models based on them and write the corresponding theories in component form using a simplifying gauge for the goldstino couplings.

  13. Minimal constrained supergravity

    Energy Technology Data Exchange (ETDEWEB)

    Cribiori, N. [Dipartimento di Fisica e Astronomia “Galileo Galilei”, Università di Padova, Via Marzolo 8, 35131 Padova (Italy); INFN, Sezione di Padova, Via Marzolo 8, 35131 Padova (Italy); Dall' Agata, G., E-mail: dallagat@pd.infn.it [Dipartimento di Fisica e Astronomia “Galileo Galilei”, Università di Padova, Via Marzolo 8, 35131 Padova (Italy); INFN, Sezione di Padova, Via Marzolo 8, 35131 Padova (Italy); Farakos, F. [Dipartimento di Fisica e Astronomia “Galileo Galilei”, Università di Padova, Via Marzolo 8, 35131 Padova (Italy); INFN, Sezione di Padova, Via Marzolo 8, 35131 Padova (Italy); Porrati, M. [Center for Cosmology and Particle Physics, Department of Physics, New York University, 4 Washington Place, New York, NY 10003 (United States)

    2017-01-10

    We describe minimal supergravity models where supersymmetry is non-linearly realized via constrained superfields. We show that the resulting actions differ from the so called “de Sitter” supergravities because we consider constraints eliminating directly the auxiliary fields of the gravity multiplet.

  14. Minimal constrained supergravity

    Directory of Open Access Journals (Sweden)

    N. Cribiori

    2017-01-01

    Full Text Available We describe minimal supergravity models where supersymmetry is non-linearly realized via constrained superfields. We show that the resulting actions differ from the so called “de Sitter” supergravities because we consider constraints eliminating directly the auxiliary fields of the gravity multiplet.

  15. Minimal constrained supergravity

    International Nuclear Information System (INIS)

    Cribiori, N.; Dall'Agata, G.; Farakos, F.; Porrati, M.

    2017-01-01

    We describe minimal supergravity models where supersymmetry is non-linearly realized via constrained superfields. We show that the resulting actions differ from the so called “de Sitter” supergravities because we consider constraints eliminating directly the auxiliary fields of the gravity multiplet.

  16. Constrained Vapor Bubble Experiment

    Science.gov (United States)

    Gokhale, Shripad; Plawsky, Joel; Wayner, Peter C., Jr.; Zheng, Ling; Wang, Ying-Xi

    2002-11-01

    Microgravity experiments on the Constrained Vapor Bubble Heat Exchanger, CVB, are being developed for the International Space Station. In particular, we present results of a precursory experimental and theoretical study of the vertical Constrained Vapor Bubble in the Earth's environment. A novel non-isothermal experimental setup was designed and built to study the transport processes in an ethanol/quartz vertical CVB system. Temperature profiles were measured using an in situ PC (personal computer)-based LabView data acquisition system via thermocouples. Film thickness profiles were measured using interferometry. A theoretical model was developed to predict the curvature profile of the stable film in the evaporator. The concept of the total amount of evaporation, which can be obtained directly by integrating the experimental temperature profile, was introduced. Experimentally measured curvature profiles are in good agreement with modeling results. For microgravity conditions, an analytical expression, which reveals an inherent relation between temperature and curvature profiles, was derived.

  17. Constrained noninformative priors

    International Nuclear Information System (INIS)

    Atwood, C.L.

    1994-10-01

    The Jeffreys noninformative prior distribution for a single unknown parameter is the distribution corresponding to a uniform distribution in the transformed model where the unknown parameter is approximately a location parameter. To obtain a prior distribution with a specified mean but with diffusion reflecting great uncertainty, a natural generalization of the noninformative prior is the distribution corresponding to the constrained maximum entropy distribution in the transformed model. Examples are given

  18. Fully electric waste collection

    CERN Multimedia

    Anaïs Schaeffer

    2015-01-01

    Since 15 June, Transvoirie, which provides waste collection services throughout French-speaking Switzerland, has been using a fully electric lorry for its collections on the CERN site – a first for the region!   Featuring a motor powered by electric batteries that charge up when the brakes are used, the new lorry that roams the CERN site is as green as can be. And it’s not only the motor that’s electric: its waste compactor and lifting mechanism are also electrically powered*, making it the first 100% electric waste collection vehicle in French-speaking Switzerland. Considering that a total of 15.5 tonnes of household waste and paper/cardboard are collected each week from the Meyrin and Prévessin sites, the benefits for the environment are clear. This improvement comes as part of CERN’s contract with Transvoirie, which stipulates that the firm must propose ways of becoming more environmentally friendly (at no extra cost to CERN). *The was...

  19. Q-deformed systems and constrained dynamics

    International Nuclear Information System (INIS)

    Shabanov, S.V.

    1993-01-01

    It is shown that quantum theories of the q-deformed harmonic oscillator and one-dimensional free q-particle (a free particle on the 'quantum' line) can be obtained by the canonical quantization of classical Hamiltonian systems with commutative phase-space variables and a non-trivial symplectic structure. In the framework of this approach, classical dynamics of a particle on the q-line coincides with the one of a free particle with friction. It is argued that q-deformed systems can be treated as ordinary mechanical systems with the second-class constraints. In particular, second-class constrained systems corresponding to the q-oscillator and q-particle are given. A possibility of formulating q-deformed systems via gauge theories (first-class constrained systems) is briefly discussed. (orig.)

  20. Ring-constrained Join

    DEFF Research Database (Denmark)

    Yiu, Man Lung; Karras, Panagiotis; Mamoulis, Nikos

    2008-01-01

    . This new operation has important applications in decision support, e.g., placing recycling stations at fair locations between restaurants and residential complexes. Clearly, RCJ is defined based on a geometric constraint but not on distances between points. Thus, our operation is fundamentally different......We introduce a novel spatial join operator, the ring-constrained join (RCJ). Given two sets P and Q of spatial points, the result of RCJ consists of pairs (p, q) (where p ε P, q ε Q) satisfying an intuitive geometric constraint: the smallest circle enclosing p and q contains no other points in P, Q...

  1. Free and constrained symplectic integrators for numerical general relativity

    International Nuclear Information System (INIS)

    Richter, Ronny; Lubich, Christian

    2008-01-01

    We consider symplectic time integrators in numerical general relativity and discuss both free and constrained evolution schemes. For free evolution of ADM-like equations we propose the use of the Stoermer-Verlet method, a standard symplectic integrator which here is explicit in the computationally expensive curvature terms. For the constrained evolution we give a formulation of the evolution equations that enforces the momentum constraints in a holonomically constrained Hamiltonian system and turns the Hamilton constraint function from a weak to a strong invariant of the system. This formulation permits the use of the constraint-preserving symplectic RATTLE integrator, a constrained version of the Stoermer-Verlet method. The behavior of the methods is illustrated on two effectively (1+1)-dimensional versions of Einstein's equations, which allow us to investigate a perturbed Minkowski problem and the Schwarzschild spacetime. We compare symplectic and non-symplectic integrators for free evolution, showing very different numerical behavior for nearly-conserved quantities in the perturbed Minkowski problem. Further we compare free and constrained evolution, demonstrating in our examples that enforcing the momentum constraints can turn an unstable free evolution into a stable constrained evolution. This is demonstrated in the stabilization of a perturbed Minkowski problem with Dirac gauge, and in the suppression of the propagation of boundary instabilities into the interior of the domain in Schwarzschild spacetime

  2. Crystallization Formulation Lab

    Data.gov (United States)

    Federal Laboratory Consortium — The Crystallization Formulation Lab fills a critical need in the process development and optimization of current and new explosives and energetic formulations. The...

  3. Affine Lie algebraic origin of constrained KP hierarchies

    International Nuclear Information System (INIS)

    Aratyn, H.; Gomes, J.F.; Zimerman, A.H.

    1994-07-01

    It is presented an affine sl(n+1) algebraic construction of the basic constrained KP hierarchy. This hierarchy is analyzed using two approaches, namely linear matrix eigenvalue problem on hermitian symmetric space and constrained KP Lax formulation and we show that these approaches are equivalent. The model is recognized to be generalized non-linear Schroedinger (GNLS) hierarchy and it is used as a building block for a new class of constrained KP hierarchies. These constrained KP hierarchies are connected via similarity-Backlund transformations and interpolate between GNLS and multi-boson KP-Toda hierarchies. The construction uncovers origin of the Toda lattice structure behind the latter hierarchy. (author). 23 refs

  4. Sharp spatially constrained inversion

    DEFF Research Database (Denmark)

    Vignoli, Giulio G.; Fiandaca, Gianluca G.; Christiansen, Anders Vest C A.V.C.

    2013-01-01

    We present sharp reconstruction of multi-layer models using a spatially constrained inversion with minimum gradient support regularization. In particular, its application to airborne electromagnetic data is discussed. Airborne surveys produce extremely large datasets, traditionally inverted...... by using smoothly varying 1D models. Smoothness is a result of the regularization constraints applied to address the inversion ill-posedness. The standard Occam-type regularized multi-layer inversion produces results where boundaries between layers are smeared. The sharp regularization overcomes...... inversions are compared against classical smooth results and available boreholes. With the focusing approach, the obtained blocky results agree with the underlying geology and allow for easier interpretation by the end-user....

  5. Multipartite fully nonlocal quantum states

    International Nuclear Information System (INIS)

    Almeida, Mafalda L.; Cavalcanti, Daniel; Scarani, Valerio; Acin, Antonio

    2010-01-01

    We present a general method for characterizing the quantum correlations obtained after local measurements on multipartite systems. Sufficient conditions for a quantum system to be fully nonlocal according to a given partition, as well as being (genuinely) multipartite fully nonlocal, are derived. These conditions allow us to identify all completely connected graph states as multipartite fully nonlocal quantum states. Moreover, we show that this feature can also be observed in mixed states: the tensor product of five copies of the Smolin state, a biseparable and bound entangled state, is multipartite fully nonlocal.

  6. Solving Fully Fuzzy Linear System of Equations in General Form

    Directory of Open Access Journals (Sweden)

    A. Yousefzadeh

    2012-06-01

    Full Text Available In this work, we propose an approach for computing the positive solution of a fully fuzzy linear system where the coefficient matrix is a fuzzy $nimes n$ matrix. To do this, we use arithmetic operations on fuzzy numbers that introduced by Kaffman in and convert the fully fuzzy linear system into two $nimes n$ and $2nimes 2n$ crisp linear systems. If the solutions of these linear systems don't satisfy in positive fuzzy solution condition, we introduce the constrained least squares problem to obtain optimal fuzzy vector solution by applying the ranking function in given fully fuzzy linear system. Using our proposed method, the fully fuzzy linear system of equations always has a solution. Finally, we illustrate the efficiency of proposed method by solving some numerical examples.

  7. Early cosmology constrained

    Energy Technology Data Exchange (ETDEWEB)

    Verde, Licia; Jimenez, Raul [Institute of Cosmos Sciences, University of Barcelona, IEEC-UB, Martí Franquès, 1, E08028 Barcelona (Spain); Bellini, Emilio [University of Oxford, Denys Wilkinson Building, Keble Road, Oxford, OX1 3RH (United Kingdom); Pigozzo, Cassio [Instituto de Física, Universidade Federal da Bahia, Salvador, BA (Brazil); Heavens, Alan F., E-mail: liciaverde@icc.ub.edu, E-mail: emilio.bellini@physics.ox.ac.uk, E-mail: cpigozzo@ufba.br, E-mail: a.heavens@imperial.ac.uk, E-mail: raul.jimenez@icc.ub.edu [Imperial Centre for Inference and Cosmology (ICIC), Imperial College, Blackett Laboratory, Prince Consort Road, London SW7 2AZ (United Kingdom)

    2017-04-01

    We investigate our knowledge of early universe cosmology by exploring how much additional energy density can be placed in different components beyond those in the ΛCDM model. To do this we use a method to separate early- and late-universe information enclosed in observational data, thus markedly reducing the model-dependency of the conclusions. We find that the 95% credibility regions for extra energy components of the early universe at recombination are: non-accelerating additional fluid density parameter Ω{sub MR} < 0.006 and extra radiation parameterised as extra effective neutrino species 2.3 < N {sub eff} < 3.2 when imposing flatness. Our constraints thus show that even when analyzing the data in this largely model-independent way, the possibility of hiding extra energy components beyond ΛCDM in the early universe is seriously constrained by current observations. We also find that the standard ruler, the sound horizon at radiation drag, can be well determined in a way that does not depend on late-time Universe assumptions, but depends strongly on early-time physics and in particular on additional components that behave like radiation. We find that the standard ruler length determined in this way is r {sub s} = 147.4 ± 0.7 Mpc if the radiation and neutrino components are standard, but the uncertainty increases by an order of magnitude when non-standard dark radiation components are allowed, to r {sub s} = 150 ± 5 Mpc.

  8. Duality in constrained location problems

    DEFF Research Database (Denmark)

    Juel, Henrik; Love, Robert F.

    1987-01-01

    The dual of a facility location problem with general norms, distance constraints, and linear constraints is formulated.......The dual of a facility location problem with general norms, distance constraints, and linear constraints is formulated....

  9. Constraining neutrinoless double beta decay

    International Nuclear Information System (INIS)

    Dorame, L.; Meloni, D.; Morisi, S.; Peinado, E.; Valle, J.W.F.

    2012-01-01

    A class of discrete flavor-symmetry-based models predicts constrained neutrino mass matrix schemes that lead to specific neutrino mass sum-rules (MSR). We show how these theories may constrain the absolute scale of neutrino mass, leading in most of the cases to a lower bound on the neutrinoless double beta decay effective amplitude.

  10. A game-theoretic formulation of the homogeneous self-reconfiguration problem

    KAUST Repository

    Pickem, Daniel

    2015-12-15

    In this paper we formulate the homogeneous two- and three-dimensional self-reconfiguration problem over discrete grids as a constrained potential game. We develop a game-theoretic learning algorithm based on the Metropolis-Hastings algorithm that solves the self-reconfiguration problem in a globally optimal fashion. Both a centralized and a fully decentralized algorithm are presented and we show that the only stochastically stable state is the potential function maximizer, i.e. the desired target configuration. These algorithms compute transition probabilities in such a way that even though each agent acts in a self-interested way, the overall collective goal of self-reconfiguration is achieved. Simulation results confirm the feasibility of our approach and show convergence to desired target configurations.

  11. A game-theoretic formulation of the homogeneous self-reconfiguration problem

    KAUST Repository

    Pickem, Daniel; Egerstedt, Magnus; Shamma, Jeff S.

    2015-01-01

    In this paper we formulate the homogeneous two- and three-dimensional self-reconfiguration problem over discrete grids as a constrained potential game. We develop a game-theoretic learning algorithm based on the Metropolis-Hastings algorithm that solves the self-reconfiguration problem in a globally optimal fashion. Both a centralized and a fully decentralized algorithm are presented and we show that the only stochastically stable state is the potential function maximizer, i.e. the desired target configuration. These algorithms compute transition probabilities in such a way that even though each agent acts in a self-interested way, the overall collective goal of self-reconfiguration is achieved. Simulation results confirm the feasibility of our approach and show convergence to desired target configurations.

  12. Constrained KP models as integrable matrix hierarchies

    International Nuclear Information System (INIS)

    Aratyn, H.; Ferreira, L.A.; Gomes, J.F.; Zimerman, A.H.

    1997-01-01

    We formulate the constrained KP hierarchy (denoted by cKP K+1,M ) as an affine [cflx sl](M+K+1) matrix integrable hierarchy generalizing the Drinfeld endash Sokolov hierarchy. Using an algebraic approach, including the graded structure of the generalized Drinfeld endash Sokolov hierarchy, we are able to find several new universal results valid for the cKP hierarchy. In particular, our method yields a closed expression for the second bracket obtained through Dirac reduction of any untwisted affine Kac endash Moody current algebra. An explicit example is given for the case [cflx sl](M+K+1), for which a closed expression for the general recursion operator is also obtained. We show how isospectral flows are characterized and grouped according to the semisimple non-regular element E of sl(M+K+1) and the content of the center of the kernel of E. copyright 1997 American Institute of Physics

  13. THE DUBINS TRAVELING SALESMAN PROBLEM WITH CONSTRAINED COLLECTING MANEUVERS

    Directory of Open Access Journals (Sweden)

    Petr Váňa

    2016-11-01

    Full Text Available In this paper, we introduce a variant of the Dubins traveling salesman problem (DTSP that is called the Dubins traveling salesman problem with constrained collecting maneuvers (DTSP-CM. In contrast to the ordinary formulation of the DTSP, in the proposed DTSP-CM, the vehicle is requested to visit each target by specified collecting maneuver to accomplish the mission. The proposed problem formulation is motivated by scenarios with unmanned aerial vehicles where particular maneuvers are necessary for accomplishing the mission, such as object dropping or data collection with sensor sensitive to changes in vehicle heading. We consider existing methods for the DTSP and propose its modifications to use these methods to address a variant of the introduced DTSP-CM, where the collecting maneuvers are constrained to straight line segments.

  14. Communication: Fully coherent quantum state hopping

    Energy Technology Data Exchange (ETDEWEB)

    Martens, Craig C., E-mail: cmartens@uci.edu [University of California, Irvine, California 92697-2025 (United States)

    2015-10-14

    In this paper, we describe a new and fully coherent stochastic surface hopping method for simulating mixed quantum-classical systems. We illustrate the approach on the simple but unforgiving problem of quantum evolution of a two-state quantum system in the limit of unperturbed pure state dynamics and for dissipative evolution in the presence of both stationary and nonstationary random environments. We formulate our approach in the Liouville representation and describe the density matrix elements by ensembles of trajectories. Population dynamics are represented by stochastic surface hops for trajectories representing diagonal density matrix elements. These are combined with an unconventional coherent stochastic hopping algorithm for trajectories representing off-diagonal quantum coherences. The latter generalizes the binary (0,1) “probability” of a trajectory to be associated with a given state to allow integers that can be negative or greater than unity in magnitude. Unlike existing surface hopping methods, the dynamics of the ensembles are fully entangled, correctly capturing the coherent and nonlocal structure of quantum mechanics.

  15. Pole shifting with constrained output feedback

    International Nuclear Information System (INIS)

    Hamel, D.; Mensah, S.; Boisvert, J.

    1984-03-01

    The concept of pole placement plays an important role in linear, multi-variable, control theory. It has received much attention since its introduction, and several pole shifting algorithms are now available. This work presents a new method which allows practical and engineering constraints such as gain limitation and controller structure to be introduced right into the pole shifting design strategy. This is achieved by formulating the pole placement problem as a constrained optimization problem. Explicit constraints (controller structure and gain limits) are defined to identify an admissible region for the feedback gain matrix. The desired pole configuration is translated into an appropriate cost function which must be closed-loop minimized. The resulting constrained optimization problem can thus be solved with optimization algorithms. The method has been implemented as an algorithmic interactive module in a computer-aided control system design package, MVPACK. The application of the method is illustrated to design controllers for an aircraft and an evaporator. The results illustrate the importance of controller structure on overall performance of a control system

  16. Ignition delay measurements of light naphtha: A fully blended low octane fuel

    KAUST Repository

    Javed, Tamour; Nasir, Ehson Fawad; Ahmed, Ahfaz; Badra, Jihad; Djebbi, Khalil; Beshir, Mohamed; Ji, Weiqi; Sarathy, Mani; Farooq, Aamir

    2016-01-01

    . To the best of our knowledge, this is the first fundamental autoignition study on the reactivity of a low-octane fully blended fuel and the use of a suitably formulated multi-component surrogate to model its behavior.

  17. Formulating viscous hydrodynamics for large velocity gradients

    International Nuclear Information System (INIS)

    Pratt, Scott

    2008-01-01

    Viscous corrections to relativistic hydrodynamics, which are usually formulated for small velocity gradients, have recently been extended from Navier-Stokes formulations to a class of treatments based on Israel-Stewart equations. Israel-Stewart treatments, which treat the spatial components of the stress-energy tensor τ ij as dynamical objects, introduce new parameters, such as the relaxation times describing nonequilibrium behavior of the elements τ ij . By considering linear response theory and entropy constraints, we show how the additional parameters are related to fluctuations of τ ij . Furthermore, the Israel-Stewart parameters are analyzed for their ability to provide stable and physical solutions for sound waves. Finally, it is shown how these parameters, which are naturally described by correlation functions in real time, might be constrained by lattice calculations, which are based on path-integral formulations in imaginary time

  18. Lightweight cryptography for constrained devices

    DEFF Research Database (Denmark)

    Alippi, Cesare; Bogdanov, Andrey; Regazzoni, Francesco

    2014-01-01

    Lightweight cryptography is a rapidly evolving research field that responds to the request for security in resource constrained devices. This need arises from crucial pervasive IT applications, such as those based on RFID tags where cost and energy constraints drastically limit the solution...... complexity, with the consequence that traditional cryptography solutions become too costly to be implemented. In this paper, we survey design strategies and techniques suitable for implementing security primitives in constrained devices....

  19. Changes in epistemic frameworks: Random or constrained?

    Directory of Open Access Journals (Sweden)

    Ananka Loubser

    2012-11-01

    Full Text Available Since the emergence of a solid anti-positivist approach in the philosophy of science, an important question has been to understand how and why epistemic frameworks change in time, are modified or even substituted. In contemporary philosophy of science three main approaches to framework-change were detected in the humanist tradition:1. In both the pre-theoretical and theoretical domains changes occur according to a rather constrained, predictable or even pre-determined pattern (e.g. Holton.2. Changes occur in a way that is more random or unpredictable and free from constraints (e.g. Kuhn, Feyerabend, Rorty, Lyotard.3. Between these approaches, a middle position can be found, attempting some kind of synthesis (e.g. Popper, Lakatos.Because this situation calls for clarification and systematisation, this article in fact tried to achieve more clarity on how changes in pre-scientific frameworks occur, as well as provided transcendental criticism of the above positions. This article suggested that the above-mentioned positions are not fully satisfactory, as change and constancy are not sufficiently integrated. An alternative model was suggested in which changes in epistemic frameworks occur according to a pattern, neither completely random nor rigidly constrained, which results in change being dynamic but not arbitrary. This alternative model is integral, rather than dialectical and therefore does not correspond to position three. 

  20. FC-TLBO: fully constrained meta-heuristic algorithm for abundance ...

    Indian Academy of Sciences (India)

    Omprakash Tembhurne

    hyperspectral unmixing; meta-heuristic approach; teaching-learning-based optimisation (TLBO). 1. ... area of research due to its real-time applications. Satellite .... describes the detailed methodology of proposed FC-TLBO. Section 4 contains ...

  1. Physics of fully ionized regions

    International Nuclear Information System (INIS)

    Flower, D.

    1975-01-01

    In this paper the term fully ionised regions is taken to embrace both planetary nebulae and the so-called 'H II' regions referred to as H + regions. Whilst these two types of gaseous nebulae are very different from an evolutionary standpoint, they are physically very similar, being characterised by photoionisation of a low-density plasma by a hot star. (Auth.)

  2. Constraining walking and custodial technicolor

    DEFF Research Database (Denmark)

    Foadi, Roshan; Frandsen, Mads Toudal; Sannino, Francesco

    2008-01-01

    We show how to constrain the physical spectrum of walking technicolor models via precision measurements and modified Weinberg sum rules. We also study models possessing a custodial symmetry for the S parameter at the effective Lagrangian level-custodial technicolor-and argue that these models...

  3. Axiomatisation of fully probabilistic design

    Czech Academy of Sciences Publication Activity Database

    Kárný, Miroslav; Kroupa, Tomáš

    2012-01-01

    Roč. 186, č. 1 (2012), s. 105-113 ISSN 0020-0255 R&D Projects: GA MŠk(CZ) 2C06001; GA ČR GA102/08/0567 Institutional research plan: CEZ:AV0Z10750506 Keywords : Bayesian decision making * Fully probabilistic design * Kullback–Leibler divergence * Unified decision making Subject RIV: BB - Applied Statistics, Operational Research Impact factor: 3.643, year: 2012 http://library.utia.cas.cz/separaty/2011/AS/karny-0367271.pdf

  4. Comparison of phase-constrained parallel MRI approaches: Analogies and differences.

    Science.gov (United States)

    Blaimer, Martin; Heim, Marius; Neumann, Daniel; Jakob, Peter M; Kannengiesser, Stephan; Breuer, Felix A

    2016-03-01

    Phase-constrained parallel MRI approaches have the potential for significantly improving the image quality of accelerated MRI scans. The purpose of this study was to investigate the properties of two different phase-constrained parallel MRI formulations, namely the standard phase-constrained approach and the virtual conjugate coil (VCC) concept utilizing conjugate k-space symmetry. Both formulations were combined with image-domain algorithms (SENSE) and a mathematical analysis was performed. Furthermore, the VCC concept was combined with k-space algorithms (GRAPPA and ESPIRiT) for image reconstruction. In vivo experiments were conducted to illustrate analogies and differences between the individual methods. Furthermore, a simple method of improving the signal-to-noise ratio by modifying the sampling scheme was implemented. For SENSE, the VCC concept was mathematically equivalent to the standard phase-constrained formulation and therefore yielded identical results. In conjunction with k-space algorithms, the VCC concept provided more robust results when only a limited amount of calibration data were available. Additionally, VCC-GRAPPA reconstructed images provided spatial phase information with full resolution. Although both phase-constrained parallel MRI formulations are very similar conceptually, there exist important differences between image-domain and k-space domain reconstructions regarding the calibration robustness and the availability of high-resolution phase information. © 2015 Wiley Periodicals, Inc.

  5. Audits of radiopharmaceutical formulations

    International Nuclear Information System (INIS)

    Castronovo, F.P. Jr.

    1992-01-01

    A procedure for auditing radiopharmaceutical formulations is described. To meet FDA guidelines regarding the quality of radiopharmaceuticals, institutional radioactive drug research committees perform audits when such drugs are formulated away from an institutional pharmacy. All principal investigators who formulate drugs outside institutional pharmacies must pass these audits before they can obtain a radiopharmaceutical investigation permit. The audit team meets with the individual who performs the formulation at the site of drug preparation to verify that drug formulations meet identity, strength, quality, and purity standards; are uniform and reproducible; and are sterile and pyrogen free. This team must contain an expert knowledgeable in the preparation of radioactive drugs; a radiopharmacist is the most qualified person for this role. Problems that have been identified by audits include lack of sterility and apyrogenicity testing, formulations that are open to the laboratory environment, failure to use pharmaceutical-grade chemicals, inadequate quality control methods or records, inadequate training of the person preparing the drug, and improper unit dose preparation. Investigational radiopharmaceutical formulations, including nonradiolabeled drugs, must be audited before they are administered to humans. A properly trained pharmacist should be a member of the audit team

  6. Physics of fully depleted CCDs

    International Nuclear Information System (INIS)

    Holland, S E; Bebek, C J; Kolbe, W F; Lee, J S

    2014-01-01

    In this work we present simple, physics-based models for two effects that have been noted in the fully depleted CCDs that are presently used in the Dark Energy Survey Camera. The first effect is the observation that the point-spread function increases slightly with the signal level. This is explained by considering the effect on charge-carrier diffusion due to the reduction in the magnitude of the channel potential as collected signal charge acts to partially neutralize the fixed charge in the depleted channel. The resulting reduced voltage drop across the carrier drift region decreases the vertical electric field and increases the carrier transit time. The second effect is the observation of low-level, concentric ring patterns seen in uniformly illuminated images. This effect is shown to be most likely due to lateral deflection of charge during the transit of the photo-generated carriers to the potential wells as a result of lateral electric fields. The lateral fields are a result of space charge in the fully depleted substrates arising from resistivity variations inherent to the growth of the high-resistivity silicon used to fabricate the CCDs

  7. Reactive decontamination formulation

    Science.gov (United States)

    Giletto, Anthony [College Station, TX; White, William [College Station, TX; Cisar, Alan J [Cypress, TX; Hitchens, G Duncan [Bryan, TX; Fyffe, James [Bryan, TX

    2003-05-27

    The present invention provides a universal decontamination formulation and method for detoxifying chemical warfare agents (CWA's) and biological warfare agents (BWA's) without producing any toxic by-products, as well as, decontaminating surfaces that have come into contact with these agents. The formulation includes a sorbent material or gel, a peroxide source, a peroxide activator, and a compound containing a mixture of KHSO.sub.5, KHSO.sub.4 and K.sub.2 SO.sub.4. The formulation is self-decontaminating and once dried can easily be wiped from the surface being decontaminated. A method for decontaminating a surface exposed to chemical or biological agents is also disclosed.

  8. An algorithm for mass matrix calculation of internally constrained molecular geometries.

    Science.gov (United States)

    Aryanpour, Masoud; Dhanda, Abhishek; Pitsch, Heinz

    2008-01-28

    Dynamic models for molecular systems require the determination of corresponding mass matrix. For constrained geometries, these computations are often not trivial but need special considerations. Here, assembling the mass matrix of internally constrained molecular structures is formulated as an optimization problem. Analytical expressions are derived for the solution of the different possible cases depending on the rank of the constraint matrix. Geometrical interpretations are further used to enhance the solution concept. As an application, we evaluate the mass matrix for a constrained molecule undergoing an electron-transfer reaction. The preexponential factor for this reaction is computed based on the harmonic model.

  9. An algorithm for mass matrix calculation of internally constrained molecular geometries

    International Nuclear Information System (INIS)

    Aryanpour, Masoud; Dhanda, Abhishek; Pitsch, Heinz

    2008-01-01

    Dynamic models for molecular systems require the determination of corresponding mass matrix. For constrained geometries, these computations are often not trivial but need special considerations. Here, assembling the mass matrix of internally constrained molecular structures is formulated as an optimization problem. Analytical expressions are derived for the solution of the different possible cases depending on the rank of the constraint matrix. Geometrical interpretations are further used to enhance the solution concept. As an application, we evaluate the mass matrix for a constrained molecule undergoing an electron-transfer reaction. The preexponential factor for this reaction is computed based on the harmonic model

  10. Complementary Constrains on Component based Multiphase Flow Problems, Should It Be Implemented Locally or Globally?

    Science.gov (United States)

    Shao, H.; Huang, Y.; Kolditz, O.

    2015-12-01

    Multiphase flow problems are numerically difficult to solve, as it often contains nonlinear Phase transition phenomena A conventional technique is to introduce the complementarity constraints where fluid properties such as liquid saturations are confined within a physically reasonable range. Based on such constraints, the mathematical model can be reformulated into a system of nonlinear partial differential equations coupled with variational inequalities. They can be then numerically handled by optimization algorithms. In this work, two different approaches utilizing the complementarity constraints based on persistent primary variables formulation[4] are implemented and investigated. The first approach proposed by Marchand et.al[1] is using "local complementary constraints", i.e. coupling the constraints with the local constitutive equations. The second approach[2],[3] , namely the "global complementary constrains", applies the constraints globally with the mass conservation equation. We will discuss how these two approaches are applied to solve non-isothermal componential multiphase flow problem with the phase change phenomenon. Several benchmarks will be presented for investigating the overall numerical performance of different approaches. The advantages and disadvantages of different models will also be concluded. References[1] E.Marchand, T.Mueller and P.Knabner. Fully coupled generalized hybrid-mixed finite element approximation of two-phase two-component flow in porous media. Part I: formulation and properties of the mathematical model, Computational Geosciences 17(2): 431-442, (2013). [2] A. Lauser, C. Hager, R. Helmig, B. Wohlmuth. A new approach for phase transitions in miscible multi-phase flow in porous media. Water Resour., 34,(2011), 957-966. [3] J. Jaffré, and A. Sboui. Henry's Law and Gas Phase Disappearance. Transp. Porous Media. 82, (2010), 521-526. [4] A. Bourgeat, M. Jurak and F. Smaï. Two-phase partially miscible flow and transport modeling in

  11. Preparation of radiopharmaceutical formulations

    International Nuclear Information System (INIS)

    Simon, J.; Garlich, J.R.; Frank, R.K.; McMillan, K.

    1998-01-01

    Radiopharmaceutical formulations for complexes comprising at least one radionuclide complexed with a ligand, or its physiologically-acceptable salts thereof, especially 153 samarium-ethylenediaminetetramethylenephosphonic acid, which optionally contains a divalent metal ion, e.g. calcium, and is frozen, thawed, and then administered by injection. Alternatively, the radiopharmaceutical formulations must contain the divalent metal and are frozen only if the time before administration is sufficiently long to cause concern for radiolysis of the ligand. 2 figs., 9 tabs

  12. Tariff formulation and equalization

    International Nuclear Information System (INIS)

    Svartsund, Trond

    2003-01-01

    The primary goal of the transmission tariff is to provide for socioeconomic use of the transmission grid. The present tariff structure is basically right. The responsibility for the formulation of the tariff resides with the local grid owner. This must take place in agreement with the current regulations which are passed by the authorities. The formulation must be adaptable to the local requirements. EBL (Norwegian Electricity Industry Association) is content with the current regulations

  13. Trends in PDE constrained optimization

    CERN Document Server

    Benner, Peter; Engell, Sebastian; Griewank, Andreas; Harbrecht, Helmut; Hinze, Michael; Rannacher, Rolf; Ulbrich, Stefan

    2014-01-01

    Optimization problems subject to constraints governed by partial differential equations (PDEs) are among the most challenging problems in the context of industrial, economical and medical applications. Almost the entire range of problems in this field of research was studied and further explored as part of the Deutsche Forschungsgemeinschaft (DFG) priority program 1253 on “Optimization with Partial Differential Equations” from 2006 to 2013. The investigations were motivated by the fascinating potential applications and challenging mathematical problems that arise in the field of PDE constrained optimization. New analytic and algorithmic paradigms have been developed, implemented and validated in the context of real-world applications. In this special volume, contributions from more than fifteen German universities combine the results of this interdisciplinary program with a focus on applied mathematics.   The book is divided into five sections on “Constrained Optimization, Identification and Control”...

  14. Lagrangian formulation of classical BMT-theory

    International Nuclear Information System (INIS)

    Pupasov-Maksimov, Andrey; Deriglazov, Alexei; Guzman, Walberto

    2013-01-01

    Full text: The most popular classical theory of electron has been formulated by Bargmann, Michel and Telegdi (BMT) in 1959. The BMT equations give classical relativistic description of a charged particle with spin and anomalous magnetic momentum moving in homogeneous electro-magnetic field. This allows to study spin dynamics of polarized beams in uniform fields. In particular, first experimental measurements of muon anomalous magnetic momentum were done using changing of helicity predicted by BMT equations. Surprisingly enough, a systematic formulation and the analysis of the BMT theory are absent in literature. In the present work we particularly fill this gap by deducing Lagrangian formulation (variational problem) for BMT equations. Various equivalent forms of Lagrangian will be discussed in details. An advantage of the obtained classical model is that the Lagrangian action describes a relativistic spinning particle without Grassmann variables, for both free and interacting cases. This implies also the possibility of canonical quantization. In the interacting case, an arbitrary electromagnetic background may be considered, which generalizes the BMT theory formulated to the case of homogeneous fields. The classical model has two local symmetries, which gives an interesting example of constrained classical dynamics. It is surprising, that the case of vanishing anomalous part of the magnetic momentum is naturally highlighted in our construction. (author)

  15. Transient thermal stresses in a circular cylinder with constrained ends

    International Nuclear Information System (INIS)

    Goshima, Takahito; Miyao, Kaju

    1986-01-01

    This paker deals with the transient thermal stresses in a finite circular cylinder constrained at both end surfaces and subjected to axisymmetric temperature distribution on the lateral surface. The thermoelastic problem is formulated in terms of a thermoelastic displacement potential and three harmonic stress functions. Numerical calculations are carried out for the case of the uniform temperature distribution on the lateral surface. The stress distributions on the constrained end and the free suface are shown graphically, and the singularity in stresses appearing at the circumferencial edge is considered. Moreover, the approximate solution based upon the plane strain theory is introduced in order to compare the rigorous one, and it is considered how the length of the cylinder and the time proceeds affect on the accuracy of the approximation. (author)

  16. Restaurant No. 1 fully renovated

    CERN Document Server

    2007-01-01

    The Restaurant No. 1 team. After several months of patience and goodwill on the part of our clients, we are delighted to announce that the major renovation work which began in September 2006 has now been completed. From 21 May 2007 we look forward to welcoming you to a completely renovated restaurant area designed with you in mind. The restaurant team wishes to thank all its clients for their patience and loyalty. Particular attention has been paid in the new design to creating a spacious serving area and providing a wider choice of dishes. The new restaurant area has been designed as an open-plan space to enable you to view all the dishes before making your selection and to move around freely from one food access point to another. It comprises user-friendly areas that fully comply with hygiene standards. From now on you will be able to pick and choose to your heart's content. We invite you to try out wok cooking or some other speciality. Or select a pizza or a plate of pasta with a choice of two sauces fr...

  17. Fully Employing Software Inspections Data

    Science.gov (United States)

    Shull, Forrest; Feldmann, Raimund L.; Seaman, Carolyn; Regardie, Myrna; Godfrey, Sally

    2009-01-01

    Software inspections provide a proven approach to quality assurance for software products of all kinds, including requirements, design, code, test plans, among others. Common to all inspections is the aim of finding and fixing defects as early as possible, and thereby providing cost savings by minimizing the amount of rework necessary later in the lifecycle. Measurement data, such as the number and type of found defects and the effort spent by the inspection team, provide not only direct feedback about the software product to the project team but are also valuable for process improvement activities. In this paper, we discuss NASA's use of software inspections and the rich set of data that has resulted. In particular, we present results from analysis of inspection data that illustrate the benefits of fully utilizing that data for process improvement at several levels. Examining such data across multiple inspections or projects allows team members to monitor and trigger cross project improvements. Such improvements may focus on the software development processes of the whole organization as well as improvements to the applied inspection process itself.

  18. Bayesian testing of constrained hypotheses

    NARCIS (Netherlands)

    Mulder, J.; Robertson, J; Kaptein, M

    2016-01-01

    Statistical hypothesis testing plays a central role in applied research to determine whether theories or expectations are supported by the data or not. Such expectations are often formulated using order constraints. For example an executive board may expect that sales representatives who wear a

  19. Stress-constrained topology optimization for compliant mechanism design

    DEFF Research Database (Denmark)

    de Leon, Daniel M.; Alexandersen, Joe; Jun, Jun S.

    2015-01-01

    This article presents an application of stress-constrained topology optimization to compliant mechanism design. An output displacement maximization formulation is used, together with the SIMP approach and a projection method to ensure convergence to nearly discrete designs. The maximum stress...... is approximated using a normalized version of the commonly-used p-norm of the effective von Mises stresses. The usual problems associated with topology optimization for compliant mechanism design: one-node and/or intermediate density hinges are alleviated by the stress constraint. However, it is also shown...

  20. Granulated decontamination formulations

    Science.gov (United States)

    Tucker, Mark D.

    2007-10-02

    A decontamination formulation and method of making that neutralizes the adverse health effects of both chemical and biological compounds, especially chemical warfare (CW) and biological warfare (BW) agents, and toxic industrial chemicals. The formulation provides solubilizing compounds that serve to effectively render the chemical and biological compounds, particularly CW and BW compounds, susceptible to attack, and at least one reactive compound that serves to attack (and detoxify or kill) the compound. The formulation includes at least one solubilizing agent, a reactive compound, a sorbent additive, and water. A highly adsorbent sorbent additive (e.g., amorphous silica, sorbitol, mannitol, etc.) is used to "dry out" one or more liquid ingredients into a dry, free-flowing powder that has an extended shelf life, and is more convenient to handle and mix in the field.

  1. Nested Sampling with Constrained Hamiltonian Monte Carlo

    OpenAIRE

    Betancourt, M. J.

    2010-01-01

    Nested sampling is a powerful approach to Bayesian inference ultimately limited by the computationally demanding task of sampling from a heavily constrained probability distribution. An effective algorithm in its own right, Hamiltonian Monte Carlo is readily adapted to efficiently sample from any smooth, constrained distribution. Utilizing this constrained Hamiltonian Monte Carlo, I introduce a general implementation of the nested sampling algorithm.

  2. Robust Layout Synthesis of a MEM Crab-Leg Resonator Using a Constrained Genetic Algorithm

    DEFF Research Database (Denmark)

    Fan, Zhun; Achiche, Sofiane

    2007-01-01

    The research work carried out in this paper introduces a robust design method for layout synthesis of MEM resonator subject to inherent geometric uncertainties such as the fabrication error on the sidewall of the structure. The robust design problem is formulated as a multi-objective constrained...

  3. Multibody motion in implicitly constrained director format with links via explicit constraints

    DEFF Research Database (Denmark)

    Nielsen, Martin Bjerre; Krenk, Steen

    2013-01-01

    A conservative time integration algorithm is developed for constrained mechanical systems of kinematically linked rigid bodies based on convected base vectors. The base vectors are represented in terms of their absolute coordinates, hence the formulation makes use of three translation components...

  4. Constrained minimization in C ++ environment

    International Nuclear Information System (INIS)

    Dymov, S.N.; Kurbatov, V.S.; Silin, I.N.; Yashchenko, S.V.

    1998-01-01

    Based on the ideas, proposed by one of the authors (I.N.Silin), the suitable software was developed for constrained data fitting. Constraints may be of the arbitrary type: equalities and inequalities. The simplest of possible ways was used. Widely known program FUMILI was realized to the C ++ language. Constraints in the form of inequalities φ (θ i ) ≥ a were taken into account by change into equalities φ (θ i ) = t and simple inequalities of type t ≥ a. The equalities were taken into account by means of quadratic penalty functions. The suitable software was tested on the model data of the ANKE setup (COSY accelerator, Forschungszentrum Juelich, Germany)

  5. Coherent states in constrained systems

    International Nuclear Information System (INIS)

    Nakamura, M.; Kojima, K.

    2001-01-01

    When quantizing the constrained systems, there often arise the quantum corrections due to the non-commutativity in the re-ordering of constraint operators in the products of operators. In the bosonic second-class constraints, furthermore, the quantum corrections caused by the uncertainty principle should be taken into account. In order to treat these corrections simultaneously, the alternative projection technique of operators is proposed by introducing the available minimal uncertainty states of the constraint operators. Using this projection technique together with the projection operator method (POM), these two kinds of quantum corrections were investigated

  6. The fully Mobile City Government Project (MCity)

    DEFF Research Database (Denmark)

    Scholl, Hans; Fidel, Raya; Mai, Jens Erik

    2006-01-01

    The Fully Mobile City Government Project, also known as MCity, is an interdisciplinary research project on the premises, requirements, and effects of fully mobile, wirelessly connected applications (FWMC). The project will develop an analytical framework for interpreting the interaction and inter......The Fully Mobile City Government Project, also known as MCity, is an interdisciplinary research project on the premises, requirements, and effects of fully mobile, wirelessly connected applications (FWMC). The project will develop an analytical framework for interpreting the interaction...

  7. Explaining evolution via constrained persistent perfect phylogeny

    Science.gov (United States)

    2014-01-01

    Background The perfect phylogeny is an often used model in phylogenetics since it provides an efficient basic procedure for representing the evolution of genomic binary characters in several frameworks, such as for example in haplotype inference. The model, which is conceptually the simplest, is based on the infinite sites assumption, that is no character can mutate more than once in the whole tree. A main open problem regarding the model is finding generalizations that retain the computational tractability of the original model but are more flexible in modeling biological data when the infinite site assumption is violated because of e.g. back mutations. A special case of back mutations that has been considered in the study of the evolution of protein domains (where a domain is acquired and then lost) is persistency, that is the fact that a character is allowed to return back to the ancestral state. In this model characters can be gained and lost at most once. In this paper we consider the computational problem of explaining binary data by the Persistent Perfect Phylogeny model (referred as PPP) and for this purpose we investigate the problem of reconstructing an evolution where some constraints are imposed on the paths of the tree. Results We define a natural generalization of the PPP problem obtained by requiring that for some pairs (character, species), neither the species nor any of its ancestors can have the character. In other words, some characters cannot be persistent for some species. This new problem is called Constrained PPP (CPPP). Based on a graph formulation of the CPPP problem, we are able to provide a polynomial time solution for the CPPP problem for matrices whose conflict graph has no edges. Using this result, we develop a parameterized algorithm for solving the CPPP problem where the parameter is the number of characters. Conclusions A preliminary experimental analysis shows that the constrained persistent perfect phylogeny model allows to

  8. Resource Management in Constrained Dynamic Situations

    Science.gov (United States)

    Seok, Jinwoo

    Resource management is considered in this dissertation for systems with limited resources, possibly combined with other system constraints, in unpredictably dynamic environments. Resources may represent fuel, power, capabilities, energy, and so on. Resource management is important for many practical systems; usually, resources are limited, and their use must be optimized. Furthermore, systems are often constrained, and constraints must be satisfied for safe operation. Simplistic resource management can result in poor use of resources and failure of the system. Furthermore, many real-world situations involve dynamic environments. Many traditional problems are formulated based on the assumptions of given probabilities or perfect knowledge of future events. However, in many cases, the future is completely unknown, and information on or probabilities about future events are not available. In other words, we operate in unpredictably dynamic situations. Thus, a method is needed to handle dynamic situations without knowledge of the future, but few formal methods have been developed to address them. Thus, the goal is to design resource management methods for constrained systems, with limited resources, in unpredictably dynamic environments. To this end, resource management is organized hierarchically into two levels: 1) planning, and 2) control. In the planning level, the set of tasks to be performed is scheduled based on limited resources to maximize resource usage in unpredictably dynamic environments. In the control level, the system controller is designed to follow the schedule by considering all the system constraints for safe and efficient operation. Consequently, this dissertation is mainly divided into two parts: 1) planning level design, based on finite state machines, and 2) control level methods, based on model predictive control. We define a recomposable restricted finite state machine to handle limited resource situations and unpredictably dynamic environments

  9. Formal language constrained path problems

    Energy Technology Data Exchange (ETDEWEB)

    Barrett, C.; Jacob, R.; Marathe, M.

    1997-07-08

    In many path finding problems arising in practice, certain patterns of edge/vertex labels in the labeled graph being traversed are allowed/preferred, while others are disallowed. Motivated by such applications as intermodal transportation planning, the authors investigate the complexity of finding feasible paths in a labeled network, where the mode choice for each traveler is specified by a formal language. The main contributions of this paper include the following: (1) the authors show that the problem of finding a shortest path between a source and destination for a traveler whose mode choice is specified as a context free language is solvable efficiently in polynomial time, when the mode choice is specified as a regular language they provide algorithms with improved space and time bounds; (2) in contrast, they show that the problem of finding simple paths between a source and a given destination is NP-hard, even when restricted to very simple regular expressions and/or very simple graphs; (3) for the class of treewidth bounded graphs, they show that (i) the problem of finding a regular language constrained simple path between source and a destination is solvable in polynomial time and (ii) the extension to finding context free language constrained simple paths is NP-complete. Several extensions of these results are presented in the context of finding shortest paths with additional constraints. These results significantly extend the results in [MW95]. As a corollary of the results, they obtain a polynomial time algorithm for the BEST k-SIMILAR PATH problem studied in [SJB97]. The previous best algorithm was given by [SJB97] and takes exponential time in the worst case.

  10. Theoretical calculation of reorganization energy for electron self-exchange reaction by constrained density functional theory and constrained equilibrium thermodynamics.

    Science.gov (United States)

    Ren, Hai-Sheng; Ming, Mei-Jun; Ma, Jian-Yi; Li, Xiang-Yuan

    2013-08-22

    Within the framework of constrained density functional theory (CDFT), the diabatic or charge localized states of electron transfer (ET) have been constructed. Based on the diabatic states, inner reorganization energy λin has been directly calculated. For solvent reorganization energy λs, a novel and reasonable nonequilibrium solvation model is established by introducing a constrained equilibrium manipulation, and a new expression of λs has been formulated. It is found that λs is actually the cost of maintaining the residual polarization, which equilibrates with the extra electric field. On the basis of diabatic states constructed by CDFT, a numerical algorithm using the new formulations with the dielectric polarizable continuum model (D-PCM) has been implemented. As typical test cases, self-exchange ET reactions between tetracyanoethylene (TCNE) and tetrathiafulvalene (TTF) and their corresponding ionic radicals in acetonitrile are investigated. The calculated reorganization energies λ are 7293 cm(-1) for TCNE/TCNE(-) and 5939 cm(-1) for TTF/TTF(+) reactions, agreeing well with available experimental results of 7250 cm(-1) and 5810 cm(-1), respectively.

  11. The cost-constrained traveling salesman problem

    Energy Technology Data Exchange (ETDEWEB)

    Sokkappa, P.R.

    1990-10-01

    The Cost-Constrained Traveling Salesman Problem (CCTSP) is a variant of the well-known Traveling Salesman Problem (TSP). In the TSP, the goal is to find a tour of a given set of cities such that the total cost of the tour is minimized. In the CCTSP, each city is given a value, and a fixed cost-constraint is specified. The objective is to find a subtour of the cities that achieves maximum value without exceeding the cost-constraint. Thus, unlike the TSP, the CCTSP requires both selection and sequencing. As a consequence, most results for the TSP cannot be extended to the CCTSP. We show that the CCTSP is NP-hard and that no K-approximation algorithm or fully polynomial approximation scheme exists, unless P = NP. We also show that several special cases are polynomially solvable. Algorithms for the CCTSP, which outperform previous methods, are developed in three areas: upper bounding methods, exact algorithms, and heuristics. We found that a bounding strategy based on the knapsack problem performs better, both in speed and in the quality of the bounds, than methods based on the assignment problem. Likewise, we found that a branch-and-bound approach using the knapsack bound was superior to a method based on a common branch-and-bound method for the TSP. In our study of heuristic algorithms, we found that, when selecting modes for inclusion in the subtour, it is important to consider the neighborhood'' of the nodes. A node with low value that brings the subtour near many other nodes may be more desirable than an isolated node of high value. We found two types of repetition to be desirable: repetitions based on randomization in the subtour buildings process, and repetitions encouraging the inclusion of different subsets of the nodes. By varying the number and type of repetitions, we can adjust the computation time required by our method to obtain algorithms that outperform previous methods.

  12. Hamiltonian formulation of QED in the superaxial gauge

    International Nuclear Information System (INIS)

    Girotti, H.O.; Rothe, H.J.

    A Hamiltonian formulation of QED in a fully fixed axial gauge is presented. The equal-time commutators for all field variables are computed and are shown to lead to the correct equations of motion. The constraints and gauge conditions hold as strong operator relations. (Author) [pt

  13. Quantization of the 2D effective gravity in the geometrical formulation

    International Nuclear Information System (INIS)

    Aoyama, S.

    1992-01-01

    There exist various formulations to discuss the 2d effective gravity: light-cone gauge formulation; geometrical formation; formulation by the constrained WZWN model; and conformal gauge formulation. In the formulations other than the last one, quantization of the 2d effective gravity is not complete in the sense that either the central charges of both sectors are not known, or one of them is known but not the other. In this paper, the authors will provide a thorough argument on quantization of the 2d effective gravity in the formulation. The argument will allow us to complete the quantization in the formation, and establish the relations among the formulations at the quantum level

  14. Systematic Equation Formulation

    DEFF Research Database (Denmark)

    Lindberg, Erik

    2007-01-01

    A tutorial giving a very simple introduction to the set-up of the equations used as a model for an electrical/electronic circuit. The aim is to find a method which is as simple and general as possible with respect to implementation in a computer program. The “Modified Nodal Approach”, MNA, and th......, and the “Controlled Source Approach”, CSA, for systematic equation formulation are investigated. It is suggested that the kernel of the P Spice program based on MNA is reprogrammed....

  15. Wavelet library for constrained devices

    Science.gov (United States)

    Ehlers, Johan Hendrik; Jassim, Sabah A.

    2007-04-01

    The wavelet transform is a powerful tool for image and video processing, useful in a range of applications. This paper is concerned with the efficiency of a certain fast-wavelet-transform (FWT) implementation and several wavelet filters, more suitable for constrained devices. Such constraints are typically found on mobile (cell) phones or personal digital assistants (PDA). These constraints can be a combination of; limited memory, slow floating point operations (compared to integer operations, most often as a result of no hardware support) and limited local storage. Yet these devices are burdened with demanding tasks such as processing a live video or audio signal through on-board capturing sensors. In this paper we present a new wavelet software library, HeatWave, that can be used efficiently for image/video processing/analysis tasks on mobile phones and PDA's. We will demonstrate that HeatWave is suitable for realtime applications with fine control and range to suit transform demands. We shall present experimental results to substantiate these claims. Finally this library is intended to be of real use and applied, hence we considered several well known and common embedded operating system platform differences; such as a lack of common routines or functions, stack limitations, etc. This makes HeatWave suitable for a range of applications and research projects.

  16. A fully coupled air foil bearing model considering friction – Theory & experiment

    DEFF Research Database (Denmark)

    von Osmanski, Alexander Sebastian; Larsen, Jon Steffen; Santos, Ilmar

    2017-01-01

    The dynamics of air foil bearings (AFBs) are not yet fully captured by any model. The recent years have, however, seen promising results from nonlinear time domain models, and simultaneously coupled formulations are now available, avoiding the previous requirements for undesirably small time steps...

  17. Drug delivery and formulations.

    Science.gov (United States)

    Breitkreutz, Jörg; Boos, Joachim

    2011-01-01

    Paediatric drug delivery is a major challenge in drug development. Because of the heterogeneous nature of the patient group, ranging from newborns to adolescents, there is a need to use appropriate excipients, drug dosage forms and delivery devices for different age groups. So far, there is a lack of suitable and safe drug formulations for children, especially for the very young and seriously ill patients. The new EU legislation will enforce paediatric clinical trials and drug development. Current advances in paediatric drug delivery include interesting new concepts such as fast-dissolving drug formulations, including orodispersible tablets and oral thin strips (buccal wafers), and multiparticulate dosage forms based on mini-tabletting or pelletization technologies. Parenteral administration is likely to remain the first choice for children in the neonatal period and for emergency cases. Alternative routes of administration include transdermal, pulmonary and nasal drug delivery systems. A few products are already available on the market, but others still need further investigations and clinical proof of concept.

  18. Ether formulations of relativity

    International Nuclear Information System (INIS)

    Duffy, M.C.

    1980-01-01

    Contemporary ether theories are surveyed and criticised, especially those formally identical to orthodox Relativity. The historical development of Relativity, Special and General, in terms of an ether, is briefly indicated. Classical interpretations of Generalized Relativity using ether are compared to Euclidean formulations using a background space. The history of a sub-group of theories, formulating a 'new' Relativity involving modified transforms, is outlined. According to the theory with which they agree, recent supposed detections of drift are classified and criticised. Cosmological evidence suggesting an ether is mentioned. Only ether theories formally identical to Relativity have been published in depth. They stand criticised as being contrary to the positivist spirit. The history of mechanical analogues is traced, from Hartley's representing gravitating matter as spherical standing waves, to recent suggestions that vortex-sponge might model electromagnetic, quantum, uncertainty and faster-than-light phenomena. Contemporary theories are particular physical theories, themselves 'second interpretations' of a primary mathematical model. Mechanical analogues are auxiliary, not necessary, to other theory, disclosing relationships between classical and non-classical descriptions of assemblies charging state. The ether-relativity polemic, part of a broader dispute about relativity, is founded on mistaken conceptions of the roles of mathematical and physical models, mechanical analogues; and a distored view of history, which indicates that ether theories have become relativistic. (author)

  19. Order-constrained linear optimization.

    Science.gov (United States)

    Tidwell, Joe W; Dougherty, Michael R; Chrabaszcz, Jeffrey S; Thomas, Rick P

    2017-11-01

    Despite the fact that data and theories in the social, behavioural, and health sciences are often represented on an ordinal scale, there has been relatively little emphasis on modelling ordinal properties. The most common analytic framework used in psychological science is the general linear model, whose variants include ANOVA, MANOVA, and ordinary linear regression. While these methods are designed to provide the best fit to the metric properties of the data, they are not designed to maximally model ordinal properties. In this paper, we develop an order-constrained linear least-squares (OCLO) optimization algorithm that maximizes the linear least-squares fit to the data conditional on maximizing the ordinal fit based on Kendall's τ. The algorithm builds on the maximum rank correlation estimator (Han, 1987, Journal of Econometrics, 35, 303) and the general monotone model (Dougherty & Thomas, 2012, Psychological Review, 119, 321). Analyses of simulated data indicate that when modelling data that adhere to the assumptions of ordinary least squares, OCLO shows minimal bias, little increase in variance, and almost no loss in out-of-sample predictive accuracy. In contrast, under conditions in which data include a small number of extreme scores (fat-tailed distributions), OCLO shows less bias and variance, and substantially better out-of-sample predictive accuracy, even when the outliers are removed. We show that the advantages of OCLO over ordinary least squares in predicting new observations hold across a variety of scenarios in which researchers must decide to retain or eliminate extreme scores when fitting data. © 2017 The British Psychological Society.

  20. A note on flow-based formulations for solving resource constrained ...

    African Journals Online (AJOL)

    2016-08-15

    Aug 15, 2016 ... Corresponding author: Centre for Business Mathematics and Informatics, ... The start time of an activity is modelled as a continuous variable, ..... distinguish between “easy” and “hard” RCSP instances are briefly described:.

  1. Extended Lagrangian formulation of charge-constrained tight-binding molecular dynamics.

    Science.gov (United States)

    Cawkwell, M J; Coe, J D; Yadav, S K; Liu, X-Y; Niklasson, A M N

    2015-06-09

    The extended Lagrangian Born-Oppenheimer molecular dynamics formalism [Niklasson, Phys. Rev. Lett., 2008, 100, 123004] has been applied to a tight-binding model under the constraint of local charge neutrality to yield microcanonical trajectories with both precise, long-term energy conservation and a reduced number of self-consistent field optimizations at each time step. The extended Lagrangian molecular dynamics formalism restores time reversal symmetry in the propagation of the electronic degrees of freedom, and it enables the efficient and accurate self-consistent optimization of the chemical potential and atomwise potential energy shifts in the on-site elements of the tight-binding Hamiltonian that are required when enforcing local charge neutrality. These capabilities are illustrated with microcanonical molecular dynamics simulations of a small metallic cluster using an sd-valent tight-binding model for titanium. The effects of weak dissipation on the propagation of the auxiliary degrees of freedom for the chemical potential and on-site Hamiltonian matrix elements that is used to counteract the accumulation of numerical noise during trajectories was also investigated.

  2. Vozy formule 1

    OpenAIRE

    Zbožínek, Adam

    2009-01-01

    Tato práce uvádí základní pravidla a předpoklady pro konstrukci a použití vozů formule 1. Hlavní zaměření je na aerodynamiku, která je nejdůležitější disciplínou v tomto motoristickém sportu, dále je tato práce zaměřena na základní faktory týkající se motoru vozu, kol, nové technologie KERS a provedení volantu. This work shows basic rules and conditions for construction and use of cars formula 1. The main part of this work focus on the aerodynamics which is the most important discipline of...

  3. Assessment of strategy formulation

    DEFF Research Database (Denmark)

    Acur, Nuran; Englyst, Linda

    2006-01-01

    of the success criteria through face-to-face interviews with 46 managers, workshops involving 40 managers, and two in-depth case studies. The success criteria have been slightly modified due to the empirical results, to yield the assessment tool. Findings – The resulting assessment tool integrates three generic...... approaches to strategy assessment, namely the goal-centred, comparative and improvement approaches, as found in the literature. Furthermore, it encompasses three phases of strategy formulation processes: strategic thinking, strategic planning and embedding of strategy. The tool reflects that the different......, but cases and managerial perceptions indicate that the need for accurate and detailed plans might be overrated in the literature, as implementation relies heavily on continuous improvement and empowerment. Concerning embedding, key aspects relate both to the goal-centred and improvement approaches, while...

  4. A Sequential Quadratically Constrained Quadratic Programming Method of Feasible Directions

    International Nuclear Information System (INIS)

    Jian Jinbao; Hu Qingjie; Tang Chunming; Zheng Haiyan

    2007-01-01

    In this paper, a sequential quadratically constrained quadratic programming method of feasible directions is proposed for the optimization problems with nonlinear inequality constraints. At each iteration of the proposed algorithm, a feasible direction of descent is obtained by solving only one subproblem which consist of a convex quadratic objective function and simple quadratic inequality constraints without the second derivatives of the functions of the discussed problems, and such a subproblem can be formulated as a second-order cone programming which can be solved by interior point methods. To overcome the Maratos effect, an efficient higher-order correction direction is obtained by only one explicit computation formula. The algorithm is proved to be globally convergent and superlinearly convergent under some mild conditions without the strict complementarity. Finally, some preliminary numerical results are reported

  5. Assessment of oscillatory stability constrained available transfer capability

    International Nuclear Information System (INIS)

    Jain, T.; Singh, S.N.; Srivastava, S.C.

    2009-01-01

    This paper utilizes a bifurcation approach to compute oscillatory stability constrained available transfer capability (ATC) in an electricity market having bilateral as well as multilateral transactions. Oscillatory instability in non-linear systems can be related to Hopf bifurcation. At the Hopf bifurcation, one pair of the critical eigenvalues of the system Jacobian reaches imaginary axis. A new optimization formulation, including Hopf bifurcation conditions, has been developed in this paper to obtain the dynamic ATC. An oscillatory stability based contingency screening index, which takes into account the impact of transactions on severity of contingency, has been utilized to identify critical contingencies to be considered in determining ATC. The proposed method has been applied for dynamic ATC determination on a 39-bus New England system and a practical 75-bus Indian system considering composite static load as well as dynamic load models. (author)

  6. Probabilistic Constrained Load Flow Considering Integration of Wind Power Generation and Electric Vehicles

    DEFF Research Database (Denmark)

    Vlachogiannis, Ioannis (John)

    2009-01-01

    A new formulation and solution of probabilistic constrained load flow (PCLF) problem suitable for modern power systems with wind power generation and electric vehicles (EV) demand or supply is represented. The developed stochastic model of EV demand/supply and the wind power generation model...... are incorporated into load flow studies. In the resulted PCLF formulation, discrete and continuous control parameters are engaged. Therefore, a hybrid learning automata system (HLAS) is developed to find the optimal offline control settings over a whole planning period of power system. The process of HLAS...

  7. Modeling the microstructural evolution during constrained sintering

    DEFF Research Database (Denmark)

    Bjørk, Rasmus; Frandsen, Henrik Lund; Tikare, V.

    A numerical model able to simulate solid state constrained sintering of a powder compact is presented. The model couples an existing kinetic Monte Carlo (kMC) model for free sintering with a finite element (FE) method for calculating stresses on a microstructural level. The microstructural response...... to the stress field as well as the FE calculation of the stress field from the microstructural evolution is discussed. The sintering behavior of two powder compacts constrained by a rigid substrate is simulated and compared to free sintering of the same samples. Constrained sintering result in a larger number...

  8. The goldstino brane, the constrained superfields and matter in N=1 supergravity

    International Nuclear Information System (INIS)

    Bandos, Igor; Heller, Markus; Kuzenko, Sergei M.; Martucci, Luca; Sorokin, Dmitri

    2016-01-01

    We show that different (brane and constrained superfield) descriptions for the Volkov-Akulov goldstino coupled to N=1, D=4 supergravity with matter produce similar wide classes of models with spontaneously broken local supersymmetry and discuss the relation between the different formulations. As with the formulations with irreducible constrained superfields, the geometric goldstino brane approach has the advantage of being manifestly off-shell supersymmetric without the need to introduce auxiliary fields. It provides an explicit solution of the nilpotent superfield constraints and avoids issues with non-Gaussian integration of auxiliary fields. We describe general couplings of the supersymmetry breaking sector, including the goldstino and other non-supersymmetric matter, to supergravity and matter supermultiplets. Among various examples, we discuss a goldstino brane contribution to the gravitino mass term and the supersymmetrization of the anti-D3-brane contribution to the effective theory of type IIB warped flux compactifications.

  9. The goldstino brane, the constrained superfields and matter in N=1 supergravity

    Energy Technology Data Exchange (ETDEWEB)

    Bandos, Igor [Department of Theoretical Physics, University of the Basque Country UPV/EHU,P.O. Box 644, 48080 Bilbao (Spain); IKERBASQUE, Basque Foundation for Science,48011, Bilbao (Spain); Heller, Markus [Dipartimento di Fisica e Astronomia “Galileo Galilei' , Università degli Studi di Padova,Via Marzolo 8, 35131 Padova (Italy); Institut für Theoretische Physik, Ruprecht-Karls-Universität,Philosophenweg 19, 69120 Heidelberg (Germany); Kuzenko, Sergei M. [School of Physics M013, The University of Western Australia35 Stirling Highway, Crawley W.A. 6009 (Australia); Martucci, Luca [Dipartimento di Fisica e Astronomia “Galileo Galilei' , Università degli Studi di Padova,Via Marzolo 8, 35131 Padova (Italy); INFN - Sezione di Padova,Via Marzolo 8, 35131 Padova (Italy); Sorokin, Dmitri [INFN - Sezione di Padova,Via Marzolo 8, 35131 Padova (Italy); Dipartimento di Fisica e Astronomia “Galileo Galilei' , Università degli Studi di Padova,Via Marzolo 8, 35131 Padova (Italy)

    2016-11-21

    We show that different (brane and constrained superfield) descriptions for the Volkov-Akulov goldstino coupled to N=1, D=4 supergravity with matter produce similar wide classes of models with spontaneously broken local supersymmetry and discuss the relation between the different formulations. As with the formulations with irreducible constrained superfields, the geometric goldstino brane approach has the advantage of being manifestly off-shell supersymmetric without the need to introduce auxiliary fields. It provides an explicit solution of the nilpotent superfield constraints and avoids issues with non-Gaussian integration of auxiliary fields. We describe general couplings of the supersymmetry breaking sector, including the goldstino and other non-supersymmetric matter, to supergravity and matter supermultiplets. Among various examples, we discuss a goldstino brane contribution to the gravitino mass term and the supersymmetrization of the anti-D3-brane contribution to the effective theory of type IIB warped flux compactifications.

  10. Mesh dependence in PDE-constrained optimisation an application in tidal turbine array layouts

    CERN Document Server

    Schwedes, Tobias; Funke, Simon W; Piggott, Matthew D

    2017-01-01

    This book provides an introduction to PDE-constrained optimisation using finite elements and the adjoint approach. The practical impact of the mathematical insights presented here are demonstrated using the realistic scenario of the optimal placement of marine power turbines, thereby illustrating the real-world relevance of best-practice Hilbert space aware approaches to PDE-constrained optimisation problems. Many optimisation problems that arise in a real-world context are constrained by partial differential equations (PDEs). That is, the system whose configuration is to be optimised follows physical laws given by PDEs. This book describes general Hilbert space formulations of optimisation algorithms, thereby facilitating optimisations whose controls are functions of space. It demonstrates the importance of methods that respect the Hilbert space structure of the problem by analysing the mathematical drawbacks of failing to do so. The approaches considered are illustrated using the optimisation problem arisin...

  11. Constrained Null Space Component Analysis for Semiblind Source Separation Problem.

    Science.gov (United States)

    Hwang, Wen-Liang; Lu, Keng-Shih; Ho, Jinn

    2018-02-01

    The blind source separation (BSS) problem extracts unknown sources from observations of their unknown mixtures. A current trend in BSS is the semiblind approach, which incorporates prior information on sources or how the sources are mixed. The constrained independent component analysis (ICA) approach has been studied to impose constraints on the famous ICA framework. We introduced an alternative approach based on the null space component (NCA) framework and referred to the approach as the c-NCA approach. We also presented the c-NCA algorithm that uses signal-dependent semidefinite operators, which is a bilinear mapping, as signatures for operator design in the c-NCA approach. Theoretically, we showed that the source estimation of the c-NCA algorithm converges with a convergence rate dependent on the decay of the sequence, obtained by applying the estimated operators on corresponding sources. The c-NCA can be formulated as a deterministic constrained optimization method, and thus, it can take advantage of solvers developed in optimization society for solving the BSS problem. As examples, we demonstrated electroencephalogram interference rejection problems can be solved by the c-NCA with proximal splitting algorithms by incorporating a sparsity-enforcing separation model and considering the case when reference signals are available.

  12. An inexact fuzzy-chance-constrained air quality management model.

    Science.gov (United States)

    Xu, Ye; Huang, Guohe; Qin, Xiaosheng

    2010-07-01

    Regional air pollution is a major concern for almost every country because it not only directly relates to economic development, but also poses significant threats to environment and public health. In this study, an inexact fuzzy-chance-constrained air quality management model (IFAMM) was developed for regional air quality management under uncertainty. IFAMM was formulated through integrating interval linear programming (ILP) within a fuzzy-chance-constrained programming (FCCP) framework and could deal with uncertainties expressed as not only possibilistic distributions but also discrete intervals in air quality management systems. Moreover, the constraints with fuzzy variables could be satisfied at different confidence levels such that various solutions with different risk and cost considerations could be obtained. The developed model was applied to a hypothetical case of regional air quality management. Six abatement technologies and sulfur dioxide (SO2) emission trading under uncertainty were taken into consideration. The results demonstrated that IFAMM could help decision-makers generate cost-effective air quality management patterns, gain in-depth insights into effects of the uncertainties, and analyze tradeoffs between system economy and reliability. The results also implied that the trading scheme could achieve lower total abatement cost than a nontrading one.

  13. Baseline LAW Glass Formulation Testing

    International Nuclear Information System (INIS)

    Kruger, Albert A.; Mooers, Cavin; Bazemore, Gina; Pegg, Ian L.; Hight, Kenneth; Lai, Shan Tao; Buechele, Andrew; Rielley, Elizabeth; Gan, Hao; Muller, Isabelle S.; Cecil, Richard

    2013-01-01

    The major objective of the baseline glass formulation work was to develop and select glass formulations that are compliant with contractual and processing requirements for each of the LAW waste streams. Other objectives of the work included preparation and characterization of glasses with respect to the properties of interest, optimization of sulfate loading in the glasses, evaluation of ability to achieve waste loading limits, testing to demonstrate compatibility of glass melts with melter materials of construction, development of glass formulations to support ILAW qualification activities, and identification of glass formulation issues with respect to contract specifications and processing requirements

  14. Asymptotic Likelihood Distribution for Correlated & Constrained Systems

    CERN Document Server

    Agarwal, Ujjwal

    2016-01-01

    It describes my work as summer student at CERN. The report discusses the asymptotic distribution of the likelihood ratio for total no. of parameters being h and 2 out of these being are constrained and correlated.

  15. Constrained bidirectional propagation and stroke segmentation

    Energy Technology Data Exchange (ETDEWEB)

    Mori, S; Gillespie, W; Suen, C Y

    1983-03-01

    A new method for decomposing a complex figure into its constituent strokes is described. This method, based on constrained bidirectional propagation, is suitable for parallel processing. Examples of its application to the segmentation of Chinese characters are presented. 9 references.

  16. Client's Constraining Factors to Construction Project Management

    African Journals Online (AJOL)

    factors as a significant system that constrains project management success of public and ... finance for the project and prompt payment for work executed; clients .... consideration of the loading patterns of these variables, the major factor is ...

  17. On the origin of constrained superfields

    Energy Technology Data Exchange (ETDEWEB)

    Dall’Agata, G. [Dipartimento di Fisica “Galileo Galilei”, Università di Padova,Via Marzolo 8, 35131 Padova (Italy); INFN, Sezione di Padova,Via Marzolo 8, 35131 Padova (Italy); Dudas, E. [Centre de Physique Théorique, École Polytechnique, CNRS, Université Paris-Saclay,F-91128 Palaiseau (France); Farakos, F. [Dipartimento di Fisica “Galileo Galilei”, Università di Padova,Via Marzolo 8, 35131 Padova (Italy); INFN, Sezione di Padova,Via Marzolo 8, 35131 Padova (Italy)

    2016-05-06

    In this work we analyze constrained superfields in supersymmetry and supergravity. We propose a constraint that, in combination with the constrained goldstino multiplet, consistently removes any selected component from a generic superfield. We also describe its origin, providing the operators whose equations of motion lead to the decoupling of such components. We illustrate our proposal by means of various examples and show how known constraints can be reproduced by our method.

  18. Stall Recovery Guidance Algorithms Based on Constrained Control Approaches

    Science.gov (United States)

    Stepanyan, Vahram; Krishnakumar, Kalmanje; Kaneshige, John; Acosta, Diana

    2016-01-01

    Aircraft loss-of-control, in particular approach to stall or fully developed stall, is a major factor contributing to aircraft safety risks, which emphasizes the need to develop algorithms that are capable of assisting the pilots to identify the problem and providing guidance to recover the aircraft. In this paper we present several stall recovery guidance algorithms, which are implemented in the background without interfering with flight control system and altering the pilot's actions. They are using input and state constrained control methods to generate guidance signals, which are provided to the pilot in the form of visual cues. It is the pilot's decision to follow these signals. The algorithms are validated in the pilot-in-the loop medium fidelity simulation experiment.

  19. Risk-constrained self-scheduling of a fuel and emission constrained power producer using rolling window procedure

    International Nuclear Information System (INIS)

    Kazempour, S. Jalal; Moghaddam, Mohsen Parsa

    2011-01-01

    This work addresses a relevant methodology for self-scheduling of a price-taker fuel and emission constrained power producer in day-ahead correlated energy, spinning reserve and fuel markets to achieve a trade-off between the expected profit and the risk versus different risk levels based on Markowitz's seminal work in the area of portfolio selection. Here, a set of uncertainties including price forecasting errors and available fuel uncertainty are considered. The latter uncertainty arises because of uncertainties in being called for reserve deployment in the spinning reserve market and availability of power plant. To tackle the price forecasting errors, variances of energy, spinning reserve and fuel prices along with their covariances which are due to markets correlation are taken into account using relevant historical data. In order to tackle available fuel uncertainty, a framework for self-scheduling referred to as rolling window is proposed. This risk-constrained self-scheduling framework is therefore formulated and solved as a mixed-integer non-linear programming problem. Furthermore, numerical results for a case study are discussed. (author)

  20. Fully Depleted Charge-Coupled Devices

    International Nuclear Information System (INIS)

    Holland, Stephen E.

    2006-01-01

    We have developed fully depleted, back-illuminated CCDs that build upon earlier research and development efforts directed towards technology development of silicon-strip detectors used in high-energy-physics experiments. The CCDs are fabricated on the same type of high-resistivity, float-zone-refined silicon that is used for strip detectors. The use of high-resistivity substrates allows for thick depletion regions, on the order of 200-300 um, with corresponding high detection efficiency for near-infrared and soft x-ray photons. We compare the fully depleted CCD to the p-i-n diode upon which it is based, and describe the use of fully depleted CCDs in astronomical and x-ray imaging applications

  1. CMOS current controlled fully balanced current conveyor

    International Nuclear Information System (INIS)

    Wang Chunhua; Zhang Qiujing; Liu Haiguang

    2009-01-01

    This paper presents a current controlled fully balanced second-generation current conveyor circuit (CF-BCCII). The proposed circuit has the traits of fully balanced architecture, and its X-Y terminals are current controllable. Based on the CFBCCII, two biquadratic universal filters are also proposed as its applications. The CFBCCII circuits and the two filters were fabricated with chartered 0.35-μm CMOS technology; with ±1.65 V power supply voltage, the total power consumption of the CFBCCII circuit is 3.6 mW. Comparisons between measured and HSpice simulation results are also given.

  2. Fully nonlinear and exact perturbations of the Friedmann world model: non-flat background

    Energy Technology Data Exchange (ETDEWEB)

    Noh, Hyerim, E-mail: hr@kasi.ac.kr [Korea Astronomy and Space Science Institute, Daejeon, 305-348 (Korea, Republic of)

    2014-07-01

    We extend the fully non-linear and exact cosmological perturbation equations in a Friedmann background universe to include the background curvature. The perturbation equations are presented in a gauge ready form, so any temporal gauge condition can be adopted freely depending on the problem to be solved. We consider the scalar, and vector perturbations without anisotropic stress. As an application, we analyze the equations in the special case of irrotational zero-pressure fluid in the comoving gauge condition. We also present the fully nonlinear formulation for a minimally coupled scalar field.

  3. Quantum Fully Homomorphic Encryption with Verification

    DEFF Research Database (Denmark)

    Alagic, Gorjan; Dulek, Yfke; Schaffner, Christian

    2017-01-01

    Fully-homomorphic encryption (FHE) enables computation on encrypted data while maintaining secrecy. Recent research has shown that such schemes exist even for quantum computation. Given the numerous applications of classical FHE (zero-knowledge proofs, secure two-party computation, obfuscation, e...

  4. Fully conditional specification in multivariate imputation

    NARCIS (Netherlands)

    van Buuren, S.; Brand, J. P.L.; Groothuis-Oudshoorn, C. G.M.; Rubin, D. B.

    2006-01-01

    The use of the Gibbs sampler with fully conditionally specified models, where the distribution of each variable given the other variables is the starting point, has become a popular method to create imputations in incomplete multivariate data. The theoretical weakness of this approach is that the

  5. Fully Integrated Biochip Platforms for Advanced Healthcare

    Directory of Open Access Journals (Sweden)

    Giovanni De Micheli

    2012-08-01

    Full Text Available Recent advances in microelectronics and biosensors are enabling developments of innovative biochips for advanced healthcare by providing fully integrated platforms for continuous monitoring of a large set of human disease biomarkers. Continuous monitoring of several human metabolites can be addressed by using fully integrated and minimally invasive devices located in the sub-cutis, typically in the peritoneal region. This extends the techniques of continuous monitoring of glucose currently being pursued with diabetic patients. However, several issues have to be considered in order to succeed in developing fully integrated and minimally invasive implantable devices. These innovative devices require a high-degree of integration, minimal invasive surgery, long-term biocompatibility, security and privacy in data transmission, high reliability, high reproducibility, high specificity, low detection limit and high sensitivity. Recent advances in the field have already proposed possible solutions for several of these issues. The aim of the present paper is to present a broad spectrum of recent results and to propose future directions of development in order to obtain fully implantable systems for the continuous monitoring of the human metabolism in advanced healthcare applications.

  6. Fully integrated biochip platforms for advanced healthcare.

    Science.gov (United States)

    Carrara, Sandro; Ghoreishizadeh, Sara; Olivo, Jacopo; Taurino, Irene; Baj-Rossi, Camilla; Cavallini, Andrea; de Beeck, Maaike Op; Dehollain, Catherine; Burleson, Wayne; Moussy, Francis Gabriel; Guiseppi-Elie, Anthony; De Micheli, Giovanni

    2012-01-01

    Recent advances in microelectronics and biosensors are enabling developments of innovative biochips for advanced healthcare by providing fully integrated platforms for continuous monitoring of a large set of human disease biomarkers. Continuous monitoring of several human metabolites can be addressed by using fully integrated and minimally invasive devices located in the sub-cutis, typically in the peritoneal region. This extends the techniques of continuous monitoring of glucose currently being pursued with diabetic patients. However, several issues have to be considered in order to succeed in developing fully integrated and minimally invasive implantable devices. These innovative devices require a high-degree of integration, minimal invasive surgery, long-term biocompatibility, security and privacy in data transmission, high reliability, high reproducibility, high specificity, low detection limit and high sensitivity. Recent advances in the field have already proposed possible solutions for several of these issues. The aim of the present paper is to present a broad spectrum of recent results and to propose future directions of development in order to obtain fully implantable systems for the continuous monitoring of the human metabolism in advanced healthcare applications.

  7. Equipment for fully automatic radiographic pipe inspection

    International Nuclear Information System (INIS)

    Basler, G.; Sperl, H.; Weinschenk, K.

    1977-01-01

    The patent describes a device for fully automatic radiographic testing of large pipes with longitudinal welds. Furthermore the invention enables automatic marking of films in radiographic inspection with regard to a ticketing of the test piece and of that part of it where testing took place. (RW) [de

  8. Faster Fully-Dynamic minimum spanning forest

    DEFF Research Database (Denmark)

    Holm, Jacob; Rotenberg, Eva; Wulff-Nilsen, Christian

    2015-01-01

    We give a new data structure for the fully-dynamic minimum spanning forest problem in simple graphs. Edge updates are supported in O(log4 n/log logn) expected amortized time per operation, improving the O(log4 n) amortized bound of Holm et al. (STOC’98, JACM’01).We also provide a deterministic data...

  9. An Evolutionary Formulation of the Crossing Number Problem

    Directory of Open Access Journals (Sweden)

    Che Sheng Gan

    2009-01-01

    Full Text Available A graph drawing algorithm is presented which results in complete graphs having minimum crossings equal to that of Guy's conjecture. It is then generalized and formulated in an evolutionary algorithm (EA to perform constrained search for the crossing numbers. The main objective of this work is to present a suitable two-dimensional scheme which can greatly reduce the complexity of finding crossing numbers by using computer. Program performance criteria are presented and discussed. It is shown that the EA implementation provides good confirmation of the predicted crossing numbers.

  10. The covariant formulation of f ( T ) gravity

    International Nuclear Information System (INIS)

    Krššák, Martin; Saridakis, Emmanuel N

    2016-01-01

    We show that the well-known problem of frame dependence and violation of local Lorentz invariance in the usual formulation of f ( T ) gravity is a consequence of neglecting the role of spin connection. We re-formulate f ( T ) gravity starting from, instead of the ‘pure tetrad’ teleparallel gravity, the covariant teleparallel gravity, using both the tetrad and the spin connection as dynamical variables, resulting in a fully covariant, consistent, and frame-independent version of f ( T ) gravity, which does not suffer from the notorious problems of the usual, pure tetrad, f ( T ) theory. We present the method to extract solutions for the most physically important cases, such as the Minkowski, the Friedmann–Robertson–Walker (FRW) and the spherically symmetric ones. We show that in covariant f ( T ) gravity we are allowed to use an arbitrary tetrad in an arbitrary coordinate system along with the corresponding spin connection, resulting always in the same physically relevant field equations. (paper)

  11. Novel Formulations for Antimicrobial Peptides

    Directory of Open Access Journals (Sweden)

    Ana Maria Carmona-Ribeiro

    2014-10-01

    Full Text Available Peptides in general hold much promise as a major ingredient in novel supramolecular assemblies. They may become essential in vaccine design, antimicrobial chemotherapy, cancer immunotherapy, food preservation, organs transplants, design of novel materials for dentistry, formulations against diabetes and other important strategical applications. This review discusses how novel formulations may improve the therapeutic index of antimicrobial peptides by protecting their activity and improving their bioavailability. The diversity of novel formulations using lipids, liposomes, nanoparticles, polymers, micelles, etc., within the limits of nanotechnology may also provide novel applications going beyond antimicrobial chemotherapy.

  12. Novel Formulations for Antimicrobial Peptides

    Science.gov (United States)

    Carmona-Ribeiro, Ana Maria; Carrasco, Letícia Dias de Melo

    2014-01-01

    Peptides in general hold much promise as a major ingredient in novel supramolecular assemblies. They may become essential in vaccine design, antimicrobial chemotherapy, cancer immunotherapy, food preservation, organs transplants, design of novel materials for dentistry, formulations against diabetes and other important strategical applications. This review discusses how novel formulations may improve the therapeutic index of antimicrobial peptides by protecting their activity and improving their bioavailability. The diversity of novel formulations using lipids, liposomes, nanoparticles, polymers, micelles, etc., within the limits of nanotechnology may also provide novel applications going beyond antimicrobial chemotherapy. PMID:25302615

  13. Fully implicit solution of large-scale non-equilibrium radiation diffusion with high order time integration

    International Nuclear Information System (INIS)

    Brown, Peter N.; Shumaker, Dana E.; Woodward, Carol S.

    2005-01-01

    We present a solution method for fully implicit radiation diffusion problems discretized on meshes having millions of spatial zones. This solution method makes use of high order in time integration techniques, inexact Newton-Krylov nonlinear solvers, and multigrid preconditioners. We explore the advantages and disadvantages of high order time integration methods for the fully implicit formulation on both two- and three-dimensional problems with tabulated opacities and highly nonlinear fusion source terms

  14. Towards weakly constrained double field theory

    Directory of Open Access Journals (Sweden)

    Kanghoon Lee

    2016-08-01

    Full Text Available We show that it is possible to construct a well-defined effective field theory incorporating string winding modes without using strong constraint in double field theory. We show that X-ray (Radon transform on a torus is well-suited for describing weakly constrained double fields, and any weakly constrained fields are represented as a sum of strongly constrained fields. Using inverse X-ray transform we define a novel binary operation which is compatible with the level matching constraint. Based on this formalism, we construct a consistent gauge transform and gauge invariant action without using strong constraint. We then discuss the relation of our result to the closed string field theory. Our construction suggests that there exists an effective field theory description for massless sector of closed string field theory on a torus in an associative truncation.

  15. Continuation of Sets of Constrained Orbit Segments

    DEFF Research Database (Denmark)

    Schilder, Frank; Brøns, Morten; Chamoun, George Chaouki

    Sets of constrained orbit segments of time continuous flows are collections of trajectories that represent a whole or parts of an invariant set. A non-trivial but simple example is a homoclinic orbit. A typical representation of this set consists of an equilibrium point of the flow and a trajectory...... that starts close and returns close to this fixed point within finite time. More complicated examples are hybrid periodic orbits of piecewise smooth systems or quasi-periodic invariant tori. Even though it is possible to define generalised two-point boundary value problems for computing sets of constrained...... orbit segments, this is very disadvantageous in practice. In this talk we will present an algorithm that allows the efficient continuation of sets of constrained orbit segments together with the solution of the full variational problem....

  16. 76 FR 36176 - Fully Developed Claim (Fully Developed Claims-Applications for Compensation, Pension, DIC, Death...

    Science.gov (United States)

    2011-06-21

    ... DEPARTMENT OF VETERANS AFFAIRS [OMB Control No. 2900-0747] Fully Developed Claim (Fully Developed Claims--Applications for Compensation, Pension, DIC, Death Pension, and/or Accrued Benefits); Correction AGENCY: Veterans Benefits Administration, Department of Veterans Affairs. ACTION: Notice; correction...

  17. Constrained principal component analysis and related techniques

    CERN Document Server

    Takane, Yoshio

    2013-01-01

    In multivariate data analysis, regression techniques predict one set of variables from another while principal component analysis (PCA) finds a subspace of minimal dimensionality that captures the largest variability in the data. How can regression analysis and PCA be combined in a beneficial way? Why and when is it a good idea to combine them? What kind of benefits are we getting from them? Addressing these questions, Constrained Principal Component Analysis and Related Techniques shows how constrained PCA (CPCA) offers a unified framework for these approaches.The book begins with four concre

  18. A multiscale finite element method for modeling fully coupled thermomechanical problems in solids

    KAUST Repository

    Sengupta, Arkaprabha; Papadopoulos, Panayiotis; Taylor, Robert L.

    2012-01-01

    This article proposes a two-scale formulation of fully coupled continuum thermomechanics using the finite element method at both scales. A monolithic approach is adopted in the solution of the momentum and energy equations. An efficient implementation of the resulting algorithm is derived that is suitable for multicore processing. The proposed method is applied with success to a strongly coupled problem involving shape-memory alloys. © 2012 John Wiley & Sons, Ltd.

  19. A multiscale finite element method for modeling fully coupled thermomechanical problems in solids

    KAUST Repository

    Sengupta, Arkaprabha

    2012-05-18

    This article proposes a two-scale formulation of fully coupled continuum thermomechanics using the finite element method at both scales. A monolithic approach is adopted in the solution of the momentum and energy equations. An efficient implementation of the resulting algorithm is derived that is suitable for multicore processing. The proposed method is applied with success to a strongly coupled problem involving shape-memory alloys. © 2012 John Wiley & Sons, Ltd.

  20. Neonates need tailored drug formulations.

    Science.gov (United States)

    Allegaert, Karel

    2013-02-08

    Drugs are very strong tools used to improve outcome in neonates. Despite this fact and in contrast to tailored perfusion equipment, incubators or ventilators for neonates, we still commonly use drug formulations initially developed for adults. We would like to make the point that drug formulations given to neonates need to be tailored for this age group. Besides the obvious need to search for active compounds that take the pathophysiology of the newborn into account, this includes the dosage and formulation. The dosage or concentration should facilitate the administration of low amounts and be flexible since clearance is lower in neonates with additional extensive between-individual variability. Formulations need to be tailored for dosage variability in the low ranges and also to the clinical characteristics of neonates. A specific focus of interest during neonatal drug development therefore is a need to quantify and limit excipient exposure based on the available knowledge of their safety or toxicity. Until such tailored vials and formulations become available, compounding practices for drug formulations in neonates should be evaluated to guarantee the correct dosing, product stability and safety.

  1. Rainwater drained through fully filled pipes

    Energy Technology Data Exchange (ETDEWEB)

    Kuhn, B; Koestel, P

    1989-02-01

    The conventional rainwater drainage system according to DIN 1986 always seems to be a point of problemacy in the building services as far as the occupancy of installation shafts and ducts is at stake. The excavation work and the necessary gravity lines are considered to be expensive. The consideration of the necessary slope complicates the installation additionally. Basing on those considerations, the raindraining system with fully filled pipes has been developed. DIN 1986, edition June 1988, part 1, point 6.1.1 allows to install rainwater pipes operated as planned, fully filled without slope. An enterprise specialised in building services investigated all system laws because only by a hydraulically exact balance, the function of the rainwater drainage system operated by negative and positive pressure can be insured. The results of those investigations are integrated in a computer program developed for this purpose.

  2. Developments towards a fully automated AMS system

    International Nuclear Information System (INIS)

    Steier, P.; Puchegger, S.; Golser, R.; Kutschera, W.; Priller, A.; Rom, W.; Wallner, A.; Wild, E.

    2000-01-01

    The possibilities of computer-assisted and automated accelerator mass spectrometry (AMS) measurements were explored. The goal of these efforts is to develop fully automated procedures for 'routine' measurements at the Vienna Environmental Research Accelerator (VERA), a dedicated 3-MV Pelletron tandem AMS facility. As a new tool for automatic tuning of the ion optics we developed a multi-dimensional optimization algorithm robust to noise, which was applied for 14 C and 10 Be. The actual isotope ratio measurements are performed in a fully automated fashion and do not require the presence of an operator. Incoming data are evaluated online and the results can be accessed via Internet. The system was used for 14 C, 10 Be, 26 Al and 129 I measurements

  3. FMFT. Fully massive four-loop tadpoles

    Energy Technology Data Exchange (ETDEWEB)

    Pikelner, Andrey [Hamburg Univ. (Germany). 2. Inst. fuer Theoretische Physik

    2017-07-15

    We present FMFT - a package written in FORM that evaluates four-loop fully massive tadpole Feynman diagrams. It is a successor of the MATAD package that has been successfully used to calculate many renormalization group functions at three-loop order in a wide range of quantum field theories especially in the Standard Model. We describe an internal structure of the package and provide some examples of its usage.

  4. Fully NLO Parton Shower in QCD

    International Nuclear Information System (INIS)

    Skrzypek, M.; Jadach, S.; Slawinska, M.; Gituliar, O.; Kusina, A.; Placzek, W.

    2011-01-01

    The project of constructing a complete NLO-level Parton Shower Monte Carlo for the QCD processes developed in IFJ PAN in Krakow is reviewed. Four issues are discussed: (1) the extension of the standard inclusive collinear factorization into a new, fully exclusive scheme; (2) reconstruction of the LO Parton Shower in the new scheme; (3) inclusion of the exclusive NLO corrections into the hard process and (4) inclusion of the exclusive NLO corrections into the evolution (ladder) part. (authors)

  5. FMFT: fully massive four-loop tadpoles

    Science.gov (United States)

    Pikelner, Andrey

    2018-03-01

    We present FMFT - a package written in FORM that evaluates four-loop fully massive tadpole Feynman diagrams. It is a successor of the MATAD package that has been successfully used to calculate many renormalization group functions at three-loop order in a wide range of quantum field theories especially in the Standard Model. We describe an internal structure of the package and provide some examples of its usage.

  6. Fully probabilistic design of hierarchical Bayesian models

    Czech Academy of Sciences Publication Activity Database

    Quinn, A.; Kárný, Miroslav; Guy, Tatiana Valentine

    2016-01-01

    Roč. 369, č. 1 (2016), s. 532-547 ISSN 0020-0255 R&D Projects: GA ČR GA13-13502S Institutional support: RVO:67985556 Keywords : Fully probabilistic design * Ideal distribution * Minimum cross-entropy principle * Bayesian conditioning * Kullback-Leibler divergence * Bayesian nonparametric modelling Subject RIV: BB - Applied Statistics, Operational Research Impact factor: 4.832, year: 2016 http://library.utia.cas.cz/separaty/2016/AS/karny-0463052.pdf

  7. Microcanonical formulation of quantum field theories

    International Nuclear Information System (INIS)

    Iwazaki, A.

    1984-03-01

    A microcanonical formulation of Euclidean quantum field theories is presented. In the formulation, correlation functions are given by a microcanonical ensemble average of fields. Furthermore, the perturbative equivalence of the formulation and the standard functional formulation is proved and the equipartition low is derived in our formulation. (author)

  8. Fully implicit kinetic modelling of collisional plasmas

    International Nuclear Information System (INIS)

    Mousseau, V.A.

    1996-05-01

    This dissertation describes a numerical technique, Matrix-Free Newton Krylov, for solving a simplified Vlasov-Fokker-Planck equation. This method is both deterministic and fully implicit, and may not have been a viable option before current developments in numerical methods. Results are presented that indicate the efficiency of the Matrix-Free Newton Krylov method for these fully-coupled, nonlinear integro-differential equations. The use and requirement for advanced differencing is also shown. To this end, implementations of Chang-Cooper differencing and flux limited Quadratic Upstream Interpolation for Convective Kinematics (QUICK) are presented. Results are given for a fully kinetic ion-electron problem with a self consistent electric field calculated from the ion and electron distribution functions. This numerical method, including advanced differencing, provides accurate solutions, which quickly converge on workstation class machines. It is demonstrated that efficient steady-state solutions can be achieved to the non-linear integro-differential equation, obtaining quadratic convergence, without incurring the large memory requirements of an integral operator. Model problems are presented which simulate plasma impinging on a plate with both high and low neutral particle recycling typical of a divertor in a Tokamak device. These model problems demonstrate the performance of the new solution method

  9. Mixed finite-element formulations in piezoelectricity and flexoelectricity.

    Science.gov (United States)

    Mao, Sheng; Purohit, Prashant K; Aravas, Nikolaos

    2016-06-01

    Flexoelectricity, the linear coupling of strain gradient and electric polarization, is inherently a size-dependent phenomenon. The energy storage function for a flexoelectric material depends not only on polarization and strain, but also strain-gradient. Thus, conventional finite-element methods formulated solely on displacement are inadequate to treat flexoelectric solids since gradients raise the order of the governing differential equations. Here, we introduce a computational framework based on a mixed formulation developed previously by one of the present authors and a colleague. This formulation uses displacement and displacement-gradient as separate variables which are constrained in a 'weighted integral sense' to enforce their known relation. We derive a variational formulation for boundary-value problems for piezo- and/or flexoelectric solids. We validate this computational framework against available exact solutions. Our new computational method is applied to more complex problems, including a plate with an elliptical hole, stationary cracks, as well as tension and shear of solids with a repeating unit cell. Our results address several issues of theoretical interest, generate predictions of experimental merit and reveal interesting flexoelectric phenomena with potential for application.

  10. On Tree-Constrained Matchings and Generalizations

    NARCIS (Netherlands)

    S. Canzar (Stefan); K. Elbassioni; G.W. Klau (Gunnar); J. Mestre

    2011-01-01

    htmlabstractWe consider the following \\textsc{Tree-Constrained Bipartite Matching} problem: Given two rooted trees $T_1=(V_1,E_1)$, $T_2=(V_2,E_2)$ and a weight function $w: V_1\\times V_2 \\mapsto \\mathbb{R}_+$, find a maximum weight matching $\\mathcal{M}$ between nodes of the two trees, such that

  11. Constrained systems described by Nambu mechanics

    International Nuclear Information System (INIS)

    Lassig, C.C.; Joshi, G.C.

    1996-01-01

    Using the framework of Nambu's generalised mechanics, we obtain a new description of constrained Hamiltonian dynamics, involving the introduction of another degree of freedom in phase space, and the necessity of defining the action integral on a world sheet. We also discuss the problem of quantizing Nambu mechanics. (authors). 5 refs

  12. Client's constraining factors to construction project management ...

    African Journals Online (AJOL)

    This study analyzed client's related factors that constrain project management success of public and private sector construction in Nigeria. Issues that concern clients in any project can not be undermined as they are the owners and the initiators of project proposals. It is assumed that success, failure or abandonment of ...

  13. Hyperbolicity and constrained evolution in linearized gravity

    International Nuclear Information System (INIS)

    Matzner, Richard A.

    2005-01-01

    Solving the 4-d Einstein equations as evolution in time requires solving equations of two types: the four elliptic initial data (constraint) equations, followed by the six second order evolution equations. Analytically the constraint equations remain solved under the action of the evolution, and one approach is to simply monitor them (unconstrained evolution). Since computational solution of differential equations introduces almost inevitable errors, it is clearly 'more correct' to introduce a scheme which actively maintains the constraints by solution (constrained evolution). This has shown promise in computational settings, but the analysis of the resulting mixed elliptic hyperbolic method has not been completely carried out. We present such an analysis for one method of constrained evolution, applied to a simple vacuum system, linearized gravitational waves. We begin with a study of the hyperbolicity of the unconstrained Einstein equations. (Because the study of hyperbolicity deals only with the highest derivative order in the equations, linearization loses no essential details.) We then give explicit analytical construction of the effect of initial data setting and constrained evolution for linearized gravitational waves. While this is clearly a toy model with regard to constrained evolution, certain interesting features are found which have relevance to the full nonlinear Einstein equations

  14. A Dynamic Programming Approach to Constrained Portfolios

    DEFF Research Database (Denmark)

    Kraft, Holger; Steffensen, Mogens

    2013-01-01

    This paper studies constrained portfolio problems that may involve constraints on the probability or the expected size of a shortfall of wealth or consumption. Our first contribution is that we solve the problems by dynamic programming, which is in contrast to the existing literature that applies...

  15. A model for optimal constrained adaptive testing

    NARCIS (Netherlands)

    van der Linden, Willem J.; Reese, Lynda M.

    2001-01-01

    A model for constrained computerized adaptive testing is proposed in which the information on the test at the ability estimate is maximized subject to a large variety of possible constraints on the contents of the test. At each item-selection step, a full test is first assembled to have maximum

  16. A model for optimal constrained adaptive testing

    NARCIS (Netherlands)

    van der Linden, Willem J.; Reese, Lynda M.

    1997-01-01

    A model for constrained computerized adaptive testing is proposed in which the information in the test at the ability estimate is maximized subject to a large variety of possible constraints on the contents of the test. At each item-selection step, a full test is first assembled to have maximum

  17. Neutron Powder Diffraction and Constrained Refinement

    DEFF Research Database (Denmark)

    Pawley, G. S.; Mackenzie, Gordon A.; Dietrich, O. W.

    1977-01-01

    The first use of a new program, EDINP, is reported. This program allows the constrained refinement of molecules in a crystal structure with neutron diffraction powder data. The structures of p-C6F4Br2 and p-C6F4I2 are determined by packing considerations and then refined with EDINP. Refinement is...

  18. Terrestrial Sagnac delay constraining modified gravity models

    Science.gov (United States)

    Karimov, R. Kh.; Izmailov, R. N.; Potapov, A. A.; Nandi, K. K.

    2018-04-01

    Modified gravity theories include f(R)-gravity models that are usually constrained by the cosmological evolutionary scenario. However, it has been recently shown that they can also be constrained by the signatures of accretion disk around constant Ricci curvature Kerr-f(R0) stellar sized black holes. Our aim here is to use another experimental fact, viz., the terrestrial Sagnac delay to constrain the parameters of specific f(R)-gravity prescriptions. We shall assume that a Kerr-f(R0) solution asymptotically describes Earth's weak gravity near its surface. In this spacetime, we shall study oppositely directed light beams from source/observer moving on non-geodesic and geodesic circular trajectories and calculate the time gap, when the beams re-unite. We obtain the exact time gap called Sagnac delay in both cases and expand it to show how the flat space value is corrected by the Ricci curvature, the mass and the spin of the gravitating source. Under the assumption that the magnitude of corrections are of the order of residual uncertainties in the delay measurement, we derive the allowed intervals for Ricci curvature. We conclude that the terrestrial Sagnac delay can be used to constrain the parameters of specific f(R) prescriptions. Despite using the weak field gravity near Earth's surface, it turns out that the model parameter ranges still remain the same as those obtained from the strong field accretion disk phenomenon.

  19. Chance constrained uncertain classification via robust optimization

    NARCIS (Netherlands)

    Ben-Tal, A.; Bhadra, S.; Bhattacharayya, C.; Saketha Nat, J.

    2011-01-01

    This paper studies the problem of constructing robust classifiers when the training is plagued with uncertainty. The problem is posed as a Chance-Constrained Program (CCP) which ensures that the uncertain data points are classified correctly with high probability. Unfortunately such a CCP turns out

  20. Integrating job scheduling and constrained network routing

    DEFF Research Database (Denmark)

    Gamst, Mette

    2010-01-01

    This paper examines the NP-hard problem of scheduling jobs on resources such that the overall profit of executed jobs is maximized. Job demand must be sent through a constrained network to the resource before execution can begin. The problem has application in grid computing, where a number...

  1. Neuroevolutionary Constrained Optimization for Content Creation

    DEFF Research Database (Denmark)

    Liapis, Antonios; Yannakakis, Georgios N.; Togelius, Julian

    2011-01-01

    and thruster types and topologies) independently of game physics and steering strategies. According to the proposed framework, the designer picks a set of requirements for the spaceship that a constrained optimizer attempts to satisfy. The constraint satisfaction approach followed is based on neuroevolution...... and survival tasks and are also visually appealing....

  2. Models of Flux Tubes from Constrained Relaxation

    Indian Academy of Sciences (India)

    tribpo

    J. Astrophys. Astr. (2000) 21, 299 302. Models of Flux Tubes from Constrained Relaxation. Α. Mangalam* & V. Krishan†, Indian Institute of Astrophysics, Koramangala,. Bangalore 560 034, India. *e mail: mangalam @ iiap. ernet. in. † e mail: vinod@iiap.ernet.in. Abstract. We study the relaxation of a compressible plasma to ...

  3. Tactile friction of topical formulations.

    Science.gov (United States)

    Skedung, L; Buraczewska-Norin, I; Dawood, N; Rutland, M W; Ringstad, L

    2016-02-01

    The tactile perception is essential for all types of topical formulations (cosmetic, pharmaceutical, medical device) and the possibility to predict the sensorial response by using instrumental methods instead of sensory testing would save time and cost at an early stage product development. Here, we report on an instrumental evaluation method using tactile friction measurements to estimate perceptual attributes of topical formulations. Friction was measured between an index finger and an artificial skin substrate after application of formulations using a force sensor. Both model formulations of liquid crystalline phase structures with significantly different tactile properties, as well as commercial pharmaceutical moisturizing creams being more tactile-similar, were investigated. Friction coefficients were calculated as the ratio of the friction force to the applied load. The structures of the model formulations and phase transitions as a result of water evaporation were identified using optical microscopy. The friction device could distinguish friction coefficients between the phase structures, as well as the commercial creams after spreading and absorption into the substrate. In addition, phase transitions resulting in alterations in the feel of the formulations could be detected. A correlation was established between skin hydration and friction coefficient, where hydrated skin gave rise to higher friction. Also a link between skin smoothening and finger friction was established for the commercial moisturizing creams, although further investigations are needed to analyse this and correlations with other sensorial attributes in more detail. The present investigation shows that tactile friction measurements have potential as an alternative or complement in the evaluation of perception of topical formulations. © 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  4. Argentina to fully privatize state owned YPF

    International Nuclear Information System (INIS)

    Anon.

    1992-01-01

    Argentina's Congress has voted to fully privatize state petroleum company Yacimientos Petroliferos Fiscales (YPF), a move the government expects to net at least $8 billion. Despite some political opposition, the vote was 119-10 in favor, with one abstention and opposition party members refusing to participate in the vote. Argentina's President Carlos Menem had threatened to authorize YPF privatization by decree if there was no quorum for a vote. YPF is responsible for 40% of Argentina's oil production. The country h as been self-sufficient in crude since 1982. Current production is 563,472 b/d, and proved reserves of oil and gas are valued at $7 billion

  5. MO-FG-CAMPUS-TeP2-01: A Graph Form ADMM Algorithm for Constrained Quadratic Radiation Treatment Planning

    Energy Technology Data Exchange (ETDEWEB)

    Liu, X; Belcher, AH; Wiersma, R [The University of Chicago, Chicago, IL (United States)

    2016-06-15

    Purpose: In radiation therapy optimization the constraints can be either hard constraints which must be satisfied or soft constraints which are included but do not need to be satisfied exactly. Currently the voxel dose constraints are viewed as soft constraints and included as a part of the objective function and approximated as an unconstrained problem. However in some treatment planning cases the constraints should be specified as hard constraints and solved by constrained optimization. The goal of this work is to present a computation efficiency graph form alternating direction method of multipliers (ADMM) algorithm for constrained quadratic treatment planning optimization and compare it with several commonly used algorithms/toolbox. Method: ADMM can be viewed as an attempt to blend the benefits of dual decomposition and augmented Lagrangian methods for constrained optimization. Various proximal operators were first constructed as applicable to quadratic IMRT constrained optimization and the problem was formulated in a graph form of ADMM. A pre-iteration operation for the projection of a point to a graph was also proposed to further accelerate the computation. Result: The graph form ADMM algorithm was tested by the Common Optimization for Radiation Therapy (CORT) dataset including TG119, prostate, liver, and head & neck cases. Both unconstrained and constrained optimization problems were formulated for comparison purposes. All optimizations were solved by LBFGS, IPOPT, Matlab built-in toolbox, CVX (implementing SeDuMi) and Mosek solvers. For unconstrained optimization, it was found that LBFGS performs the best, and it was 3–5 times faster than graph form ADMM. However, for constrained optimization, graph form ADMM was 8 – 100 times faster than the other solvers. Conclusion: A graph form ADMM can be applied to constrained quadratic IMRT optimization. It is more computationally efficient than several other commercial and noncommercial optimizers and it also

  6. Constrained Deep Weak Supervision for Histopathology Image Segmentation.

    Science.gov (United States)

    Jia, Zhipeng; Huang, Xingyi; Chang, Eric I-Chao; Xu, Yan

    2017-11-01

    In this paper, we develop a new weakly supervised learning algorithm to learn to segment cancerous regions in histopathology images. This paper is under a multiple instance learning (MIL) framework with a new formulation, deep weak supervision (DWS); we also propose an effective way to introduce constraints to our neural networks to assist the learning process. The contributions of our algorithm are threefold: 1) we build an end-to-end learning system that segments cancerous regions with fully convolutional networks (FCNs) in which image-to-image weakly-supervised learning is performed; 2) we develop a DWS formulation to exploit multi-scale learning under weak supervision within FCNs; and 3) constraints about positive instances are introduced in our approach to effectively explore additional weakly supervised information that is easy to obtain and enjoy a significant boost to the learning process. The proposed algorithm, abbreviated as DWS-MIL, is easy to implement and can be trained efficiently. Our system demonstrates the state-of-the-art results on large-scale histopathology image data sets and can be applied to various applications in medical imaging beyond histopathology images, such as MRI, CT, and ultrasound images.

  7. Decontamination formulation with sorbent additive

    Science.gov (United States)

    Tucker; Mark D. , Comstock; Robert H.

    2007-10-16

    A decontamination formulation and method of making that neutralizes the adverse health effects of both chemical and biological compounds, especially chemical warfare (CW) and biological warfare (BW) agents, and toxic industrial chemicals. The formulation provides solubilizing compounds that serve to effectively render the chemical and biological compounds, particularly CW and BW compounds, susceptible to attack, and at least one reactive compound that serves to attack (and detoxify or kill) the compound. The formulation includes at least one solubilizing agent, a reactive compound, a bleaching activator, a sorbent additive, and water. The highly adsorbent, water-soluble sorbent additive (e.g., sorbitol or mannitol) is used to "dry out" one or more liquid ingredients, such as the liquid bleaching activator (e.g., propylene glycol diacetate or glycerol diacetate) and convert the activator into a dry, free-flowing powder that has an extended shelf life, and is more convenient to handle and mix in the field.

  8. Positive solution of non-square fully Fuzzy linear system of equation in general form using least square method

    Directory of Open Access Journals (Sweden)

    Reza Ezzati

    2014-08-01

    Full Text Available In this paper, we propose the least square method for computing the positive solution of a non-square fully fuzzy linear system. To this end, we use Kaffman' arithmetic operations on fuzzy numbers \\cite{17}. Here, considered existence of exact solution using pseudoinverse, if they are not satisfy in positive solution condition, we will compute fuzzy vector core and then we will obtain right and left spreads of positive fuzzy vector by introducing constrained least squares problem. Using our proposed method, non-square fully fuzzy linear system of equations always has a solution. Finally, we illustrate the efficiency of proposed method by solving some numerical examples.

  9. Solving discretely-constrained MPEC problems with applications in electric power markets

    International Nuclear Information System (INIS)

    Gabriel, Steven A.; Leuthold, Florian U.

    2010-01-01

    Many of the European energy markets are characterized by dominant players that own a large share of their respective countries' generation capacities. In addition to that, there is a significant lack of cross-border transmission capacity. Combining both facts justifies the assumption that these dominant players are able to influence the market outcome of an internal European energy market due to strategic behavior. In this paper, we present a mathematical formulation in order to solve a Stackelberg game for a network-constrained energy market using integer programming. The strategic player is the Stackelberg leader and the independent system operator (including the decisions of the competitive fringe firms) acts as follower. We assume that there is one strategic player which results in a mathematical program with equilibrium constraints (MPEC). This MPEC is reformulated as mixed-integer linear program (MILP) by using disjunctive constraints and linearization. The MILP formulation gives the opportunity to solve the problems reliably and paves the way to add discrete constraints to the original MPEC formulation which can be used in order to solve discretely-constrained mathematical programs with equilibrium constraints (DC-MPECs). We report computational results for a small illustrative network as well as a stylized Western European grid with realistic data. (author)

  10. Solving discretely-constrained MPEC problems with applications in electric power markets

    Energy Technology Data Exchange (ETDEWEB)

    Gabriel, Steven A. [1143 Glenn L. Martin Hall, Department of Civil and Environmental Engineering, University of Maryland, College Park, MD 20742-3021 (United States); Leuthold, Florian U. [Chair of Energy Economics and Public Sector Management, Dresden University of Technology, 01069 Dresden (Germany)

    2010-01-15

    Many of the European energy markets are characterized by dominant players that own a large share of their respective countries' generation capacities. In addition to that, there is a significant lack of cross-border transmission capacity. Combining both facts justifies the assumption that these dominant players are able to influence the market outcome of an internal European energy market due to strategic behavior. In this paper, we present a mathematical formulation in order to solve a Stackelberg game for a network-constrained energy market using integer programming. The strategic player is the Stackelberg leader and the independent system operator (including the decisions of the competitive fringe firms) acts as follower. We assume that there is one strategic player which results in a mathematical program with equilibrium constraints (MPEC). This MPEC is reformulated as mixed-integer linear program (MILP) by using disjunctive constraints and linearization. The MILP formulation gives the opportunity to solve the problems reliably and paves the way to add discrete constraints to the original MPEC formulation which can be used in order to solve discretely-constrained mathematical programs with equilibrium constraints (DC-MPECs). We report computational results for a small illustrative network as well as a stylized Western European grid with realistic data. (author)

  11. A penalty method for PDE-constrained optimization in inverse problems

    International Nuclear Information System (INIS)

    Leeuwen, T van; Herrmann, F J

    2016-01-01

    Many inverse and parameter estimation problems can be written as PDE-constrained optimization problems. The goal is to infer the parameters, typically coefficients of the PDE, from partial measurements of the solutions of the PDE for several right-hand sides. Such PDE-constrained problems can be solved by finding a stationary point of the Lagrangian, which entails simultaneously updating the parameters and the (adjoint) state variables. For large-scale problems, such an all-at-once approach is not feasible as it requires storing all the state variables. In this case one usually resorts to a reduced approach where the constraints are explicitly eliminated (at each iteration) by solving the PDEs. These two approaches, and variations thereof, are the main workhorses for solving PDE-constrained optimization problems arising from inverse problems. In this paper, we present an alternative method that aims to combine the advantages of both approaches. Our method is based on a quadratic penalty formulation of the constrained optimization problem. By eliminating the state variable, we develop an efficient algorithm that has roughly the same computational complexity as the conventional reduced approach while exploiting a larger search space. Numerical results show that this method indeed reduces some of the nonlinearity of the problem and is less sensitive to the initial iterate. (paper)

  12. Fully 3D GPU PET reconstruction

    Energy Technology Data Exchange (ETDEWEB)

    Herraiz, J.L., E-mail: joaquin@nuclear.fis.ucm.es [Grupo de Fisica Nuclear, Departmento Fisica Atomica, Molecular y Nuclear, Universidad Complutense de Madrid (Spain); Espana, S. [Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, MA (United States); Cal-Gonzalez, J. [Grupo de Fisica Nuclear, Departmento Fisica Atomica, Molecular y Nuclear, Universidad Complutense de Madrid (Spain); Vaquero, J.J. [Departmento de Bioingenieria e Ingenieria Espacial, Universidad Carlos III, Madrid (Spain); Desco, M. [Departmento de Bioingenieria e Ingenieria Espacial, Universidad Carlos III, Madrid (Spain); Unidad de Medicina y Cirugia Experimental, Hospital General Universitario Gregorio Maranon, Madrid (Spain); Udias, J.M. [Grupo de Fisica Nuclear, Departmento Fisica Atomica, Molecular y Nuclear, Universidad Complutense de Madrid (Spain)

    2011-08-21

    Fully 3D iterative tomographic image reconstruction is computationally very demanding. Graphics Processing Unit (GPU) has been proposed for many years as potential accelerators in complex scientific problems, but it has not been used until the recent advances in the programmability of GPUs that the best available reconstruction codes have started to be implemented to be run on GPUs. This work presents a GPU-based fully 3D PET iterative reconstruction software. This new code may reconstruct sinogram data from several commercially available PET scanners. The most important and time-consuming parts of the code, the forward and backward projection operations, are based on an accurate model of the scanner obtained with the Monte Carlo code PeneloPET and they have been massively parallelized on the GPU. For the PET scanners considered, the GPU-based code is more than 70 times faster than a similar code running on a single core of a fast CPU, obtaining in both cases the same images. The code has been designed to be easily adapted to reconstruct sinograms from any other PET scanner, including scanner prototypes.

  13. Fully 3D GPU PET reconstruction

    International Nuclear Information System (INIS)

    Herraiz, J.L.; Espana, S.; Cal-Gonzalez, J.; Vaquero, J.J.; Desco, M.; Udias, J.M.

    2011-01-01

    Fully 3D iterative tomographic image reconstruction is computationally very demanding. Graphics Processing Unit (GPU) has been proposed for many years as potential accelerators in complex scientific problems, but it has not been used until the recent advances in the programmability of GPUs that the best available reconstruction codes have started to be implemented to be run on GPUs. This work presents a GPU-based fully 3D PET iterative reconstruction software. This new code may reconstruct sinogram data from several commercially available PET scanners. The most important and time-consuming parts of the code, the forward and backward projection operations, are based on an accurate model of the scanner obtained with the Monte Carlo code PeneloPET and they have been massively parallelized on the GPU. For the PET scanners considered, the GPU-based code is more than 70 times faster than a similar code running on a single core of a fast CPU, obtaining in both cases the same images. The code has been designed to be easily adapted to reconstruct sinograms from any other PET scanner, including scanner prototypes.

  14. Fully populated VCM or the hidden parameter

    Directory of Open Access Journals (Sweden)

    Kermarrec G.

    2017-11-01

    Full Text Available Least-squares estimates are trustworthy with minimal variance if the correct stochastic model is used. Due to computational burden, diagonal models that neglect correlations are preferred to describe the elevation dependency of the variance of GPS observations. In this contribution, an improved stochastic model based on a parametric function to take correlations between GPS phase observations into account is presented. Built on an adapted and flexible Mátern function accounting for spatiotemporal variabilities, its parameters can be fixed thanks to Maximum Likelihood Estimation or chosen apriori to model turbulent tropospheric refractivity fluctuations. In this contribution, we will show in which cases and under which conditions corresponding fully populated variance covariance matrices (VCM replace the estimation of a tropospheric parameter. For this equivalence “augmented functional versus augmented stochastic model” to hold, the VCM should be made sufficiently largewhich corresponds to computing small batches of observations. A case study with observations from a medium baseline of 80 km divided into batches of 600 s shows improvement of up to 100 mm for the 3Drms when fully populated VCM are used compared with an elevation dependent diagonal model. It confirms the strong potential of such matrices to improve the least-squares solution, particularly when ambiguities are let float.

  15. Fully CMOS-compatible titanium nitride nanoantennas

    Energy Technology Data Exchange (ETDEWEB)

    Briggs, Justin A., E-mail: jabriggs@stanford.edu [Department of Applied Physics, Stanford University, 348 Via Pueblo Mall, Stanford, California 94305 (United States); Department of Materials Science and Engineering, Stanford University, 496 Lomita Mall, Stanford, California 94305 (United States); Naik, Gururaj V.; Baum, Brian K.; Dionne, Jennifer A. [Department of Materials Science and Engineering, Stanford University, 496 Lomita Mall, Stanford, California 94305 (United States); Petach, Trevor A.; Goldhaber-Gordon, David [Department of Physics, Stanford University, 382 Via Pueblo Mall, Stanford, California 94305 (United States)

    2016-02-01

    CMOS-compatible fabrication of plasmonic materials and devices will accelerate the development of integrated nanophotonics for information processing applications. Using low-temperature plasma-enhanced atomic layer deposition (PEALD), we develop a recipe for fully CMOS-compatible titanium nitride (TiN) that is plasmonic in the visible and near infrared. Films are grown on silicon, silicon dioxide, and epitaxially on magnesium oxide substrates. By optimizing the plasma exposure per growth cycle during PEALD, carbon and oxygen contamination are reduced, lowering undesirable loss. We use electron beam lithography to pattern TiN nanopillars with varying diameters on silicon in large-area arrays. In the first reported single-particle measurements on plasmonic TiN, we demonstrate size-tunable darkfield scattering spectroscopy in the visible and near infrared regimes. The optical properties of this CMOS-compatible material, combined with its high melting temperature and mechanical durability, comprise a step towards fully CMOS-integrated nanophotonic information processing.

  16. Self-constrained inversion of potential fields

    Science.gov (United States)

    Paoletti, V.; Ialongo, S.; Florio, G.; Fedi, M.; Cella, F.

    2013-11-01

    We present a potential-field-constrained inversion procedure based on a priori information derived exclusively from the analysis of the gravity and magnetic data (self-constrained inversion). The procedure is designed to be applied to underdetermined problems and involves scenarios where the source distribution can be assumed to be of simple character. To set up effective constraints, we first estimate through the analysis of the gravity or magnetic field some or all of the following source parameters: the source depth-to-the-top, the structural index, the horizontal position of the source body edges and their dip. The second step is incorporating the information related to these constraints in the objective function as depth and spatial weighting functions. We show, through 2-D and 3-D synthetic and real data examples, that potential field-based constraints, for example, structural index, source boundaries and others, are usually enough to obtain substantial improvement in the density and magnetization models.

  17. Cosmogenic photons strongly constrain UHECR source models

    Directory of Open Access Journals (Sweden)

    van Vliet Arjen

    2017-01-01

    Full Text Available With the newest version of our Monte Carlo code for ultra-high-energy cosmic ray (UHECR propagation, CRPropa 3, the flux of neutrinos and photons due to interactions of UHECRs with extragalactic background light can be predicted. Together with the recently updated data for the isotropic diffuse gamma-ray background (IGRB by Fermi LAT, it is now possible to severely constrain UHECR source models. The evolution of the UHECR sources especially plays an important role in the determination of the expected secondary photon spectrum. Pure proton UHECR models are already strongly constrained, primarily by the highest energy bins of Fermi LAT’s IGRB, as long as their number density is not strongly peaked at recent times.

  18. A constrained supersymmetric left-right model

    Energy Technology Data Exchange (ETDEWEB)

    Hirsch, Martin [AHEP Group, Instituto de Física Corpuscular - C.S.I.C./Universitat de València, Edificio de Institutos de Paterna, Apartado 22085, E-46071 València (Spain); Krauss, Manuel E. [Bethe Center for Theoretical Physics & Physikalisches Institut der Universität Bonn, Nussallee 12, 53115 Bonn (Germany); Institut für Theoretische Physik und Astronomie, Universität Würzburg,Emil-Hilb-Weg 22, 97074 Wuerzburg (Germany); Opferkuch, Toby [Bethe Center for Theoretical Physics & Physikalisches Institut der Universität Bonn, Nussallee 12, 53115 Bonn (Germany); Porod, Werner [Institut für Theoretische Physik und Astronomie, Universität Würzburg,Emil-Hilb-Weg 22, 97074 Wuerzburg (Germany); Staub, Florian [Theory Division, CERN,1211 Geneva 23 (Switzerland)

    2016-03-02

    We present a supersymmetric left-right model which predicts gauge coupling unification close to the string scale and extra vector bosons at the TeV scale. The subtleties in constructing a model which is in agreement with the measured quark masses and mixing for such a low left-right breaking scale are discussed. It is shown that in the constrained version of this model radiative breaking of the gauge symmetries is possible and a SM-like Higgs is obtained. Additional CP-even scalars of a similar mass or even much lighter are possible. The expected mass hierarchies for the supersymmetric states differ clearly from those of the constrained MSSM. In particular, the lightest down-type squark, which is a mixture of the sbottom and extra vector-like states, is always lighter than the stop. We also comment on the model’s capability to explain current anomalies observed at the LHC.

  19. Coding for Two Dimensional Constrained Fields

    DEFF Research Database (Denmark)

    Laursen, Torben Vaarbye

    2006-01-01

    a first order model to model higher order constraints by the use of an alphabet extension. We present an iterative method that based on a set of conditional probabilities can help in choosing the large numbers of parameters of the model in order to obtain a stationary model. Explicit results are given...... for the No Isolated Bits constraint. Finally we present a variation of the encoding scheme of bit-stuffing that is applicable to the class of checkerboard constrained fields. It is possible to calculate the entropy of the coding scheme thus obtaining lower bounds on the entropy of the fields considered. These lower...... bounds are very tight for the Run-Length limited fields. Explicit bounds are given for the diamond constrained field as well....

  20. Communication Schemes with Constrained Reordering of Resources

    DEFF Research Database (Denmark)

    Popovski, Petar; Utkovski, Zoran; Trillingsgaard, Kasper Fløe

    2013-01-01

    This paper introduces a communication model inspired by two practical scenarios. The first scenario is related to the concept of protocol coding, where information is encoded in the actions taken by an existing communication protocol. We investigate strategies for protocol coding via combinatorial...... reordering of the labelled user resources (packets, channels) in an existing, primary system. However, the degrees of freedom of the reordering are constrained by the operation of the primary system. The second scenario is related to communication systems with energy harvesting, where the transmitted signals...... are constrained by the energy that is available through the harvesting process. We have introduced a communication model that covers both scenarios and elicits their key feature, namely the constraints of the primary system or the harvesting process. We have shown how to compute the capacity of the channels...

  1. Online constrained model-based reinforcement learning

    CSIR Research Space (South Africa)

    Van Niekerk, B

    2017-08-01

    Full Text Available Constrained Model-based Reinforcement Learning Benjamin van Niekerk School of Computer Science University of the Witwatersrand South Africa Andreas Damianou∗ Amazon.com Cambridge, UK Benjamin Rosman Council for Scientific and Industrial Research, and School... MULTIPLE SHOOTING Using direct multiple shooting (Bock and Plitt, 1984), problem (1) can be transformed into a structured non- linear program (NLP). First, the time horizon [t0, t0 + T ] is partitioned into N equal subintervals [tk, tk+1] for k = 0...

  2. Constraining supergravity models from gluino production

    International Nuclear Information System (INIS)

    Barbieri, R.; Gamberini, G.; Giudice, G.F.; Ridolfi, G.

    1988-01-01

    The branching ratios for gluino decays g tilde → qanti qΧ, g tilde → gΧ into a stable undetected neutralino are computed as functions of the relevant parameters of the underlying supergravity theory. A simple way of constraining supergravity models from gluino production emerges. The effectiveness of hadronic versus e + e - colliders in the search for supersymmetry can be directly compared. (orig.)

  3. Cosmicflows Constrained Local UniversE Simulations

    Science.gov (United States)

    Sorce, Jenny G.; Gottlöber, Stefan; Yepes, Gustavo; Hoffman, Yehuda; Courtois, Helene M.; Steinmetz, Matthias; Tully, R. Brent; Pomarède, Daniel; Carlesi, Edoardo

    2016-01-01

    This paper combines observational data sets and cosmological simulations to generate realistic numerical replicas of the nearby Universe. The latter are excellent laboratories for studies of the non-linear process of structure formation in our neighbourhood. With measurements of radial peculiar velocities in the local Universe (cosmicflows-2) and a newly developed technique, we produce Constrained Local UniversE Simulations (CLUES). To assess the quality of these constrained simulations, we compare them with random simulations as well as with local observations. The cosmic variance, defined as the mean one-sigma scatter of cell-to-cell comparison between two fields, is significantly smaller for the constrained simulations than for the random simulations. Within the inner part of the box where most of the constraints are, the scatter is smaller by a factor of 2 to 3 on a 5 h-1 Mpc scale with respect to that found for random simulations. This one-sigma scatter obtained when comparing the simulated and the observation-reconstructed velocity fields is only 104 ± 4 km s-1, I.e. the linear theory threshold. These two results demonstrate that these simulations are in agreement with each other and with the observations of our neighbourhood. For the first time, simulations constrained with observational radial peculiar velocities resemble the local Universe up to a distance of 150 h-1 Mpc on a scale of a few tens of megaparsecs. When focusing on the inner part of the box, the resemblance with our cosmic neighbourhood extends to a few megaparsecs (<5 h-1 Mpc). The simulations provide a proper large-scale environment for studies of the formation of nearby objects.

  4. Statistical mechanics of budget-constrained auctions

    OpenAIRE

    Altarelli, F.; Braunstein, A.; Realpe-Gomez, J.; Zecchina, R.

    2009-01-01

    Finding the optimal assignment in budget-constrained auctions is a combinatorial optimization problem with many important applications, a notable example being the sale of advertisement space by search engines (in this context the problem is often referred to as the off-line AdWords problem). Based on the cavity method of statistical mechanics, we introduce a message passing algorithm that is capable of solving efficiently random instances of the problem extracted from a natural distribution,...

  5. Constraining neutron star matter with Quantum Chromodynamics

    CERN Document Server

    Kurkela, Aleksi; Schaffner-Bielich, Jurgen; Vuorinen, Aleksi

    2014-01-01

    In recent years, there have been several successful attempts to constrain the equation of state of neutron star matter using input from low-energy nuclear physics and observational data. We demonstrate that significant further restrictions can be placed by additionally requiring the pressure to approach that of deconfined quark matter at high densities. Remarkably, the new constraints turn out to be highly insensitive to the amount --- or even presence --- of quark matter inside the stars.

  6. Resource Constrained Project Scheduling Subject to Due Dates: Preemption Permitted with Penalty

    Directory of Open Access Journals (Sweden)

    Behrouz Afshar-Nadjafi

    2014-01-01

    Full Text Available Extensive research works have been carried out in resource constrained project scheduling problem. However, scarce researches have studied the problems in which a setup cost must be incurred if activities are preempted. In this research, we investigate the resource constrained project scheduling problem to minimize the total project cost, considering earliness-tardiness and preemption penalties. A mixed integer programming formulation is proposed for the problem. The resulting problem is NP-hard. So, we try to obtain a satisfying solution using simulated annealing (SA algorithm. The efficiency of the proposed algorithm is tested based on 150 randomly produced examples. Statistical comparison in terms of the computational times and objective function indicates that the proposed algorithm is efficient and effective.

  7. The Combinatorial Multi-Mode Resource Constrained Multi-Project Scheduling Problem

    Directory of Open Access Journals (Sweden)

    Denis Pinha

    2016-11-01

    Full Text Available This paper presents the formulation and solution of the Combinatorial Multi-Mode Resource Constrained Multi-Project Scheduling Problem. The focus of the proposed method is not on finding a single optimal solution, instead on presenting multiple feasible solutions, with cost and duration information to the project manager. The motivation for developing such an approach is due in part to practical situations where the definition of optimal changes on a regular basis. The proposed approach empowers the project manager to determine what is optimal, on a given day, under the current constraints, such as, change of priorities, lack of skilled worker. The proposed method utilizes a simulation approach to determine feasible solutions, under the current constraints. Resources can be non-consumable, consumable, or doubly constrained. The paper also presents a real-life case study dealing with scheduling of ship repair activities.

  8. Structure-constrained sparse canonical correlation analysis with an application to microbiome data analysis.

    Science.gov (United States)

    Chen, Jun; Bushman, Frederic D; Lewis, James D; Wu, Gary D; Li, Hongzhe

    2013-04-01

    Motivated by studying the association between nutrient intake and human gut microbiome composition, we developed a method for structure-constrained sparse canonical correlation analysis (ssCCA) in a high-dimensional setting. ssCCA takes into account the phylogenetic relationships among bacteria, which provides important prior knowledge on evolutionary relationships among bacterial taxa. Our ssCCA formulation utilizes a phylogenetic structure-constrained penalty function to impose certain smoothness on the linear coefficients according to the phylogenetic relationships among the taxa. An efficient coordinate descent algorithm is developed for optimization. A human gut microbiome data set is used to illustrate this method. Both simulations and real data applications show that ssCCA performs better than the standard sparse CCA in identifying meaningful variables when there are structures in the data.

  9. Coevolutionary particle swarm optimization using Gaussian distribution for solving constrained optimization problems.

    Science.gov (United States)

    Krohling, Renato A; Coelho, Leandro dos Santos

    2006-12-01

    In this correspondence, an approach based on coevolutionary particle swarm optimization to solve constrained optimization problems formulated as min-max problems is presented. In standard or canonical particle swarm optimization (PSO), a uniform probability distribution is used to generate random numbers for the accelerating coefficients of the local and global terms. We propose a Gaussian probability distribution to generate the accelerating coefficients of PSO. Two populations of PSO using Gaussian distribution are used on the optimization algorithm that is tested on a suite of well-known benchmark constrained optimization problems. Results have been compared with the canonical PSO (constriction factor) and with a coevolutionary genetic algorithm. Simulation results show the suitability of the proposed algorithm in terms of effectiveness and robustness.

  10. A chance-constrained stochastic approach to intermodal container routing problems.

    Science.gov (United States)

    Zhao, Yi; Liu, Ronghui; Zhang, Xi; Whiteing, Anthony

    2018-01-01

    We consider a container routing problem with stochastic time variables in a sea-rail intermodal transportation system. The problem is formulated as a binary integer chance-constrained programming model including stochastic travel times and stochastic transfer time, with the objective of minimising the expected total cost. Two chance constraints are proposed to ensure that the container service satisfies ship fulfilment and cargo on-time delivery with pre-specified probabilities. A hybrid heuristic algorithm is employed to solve the binary integer chance-constrained programming model. Two case studies are conducted to demonstrate the feasibility of the proposed model and to analyse the impact of stochastic variables and chance-constraints on the optimal solution and total cost.

  11. Constraining the mass of the Local Group

    Science.gov (United States)

    Carlesi, Edoardo; Hoffman, Yehuda; Sorce, Jenny G.; Gottlöber, Stefan

    2017-03-01

    The mass of the Local Group (LG) is a crucial parameter for galaxy formation theories. However, its observational determination is challenging - its mass budget is dominated by dark matter that cannot be directly observed. To meet this end, the posterior distributions of the LG and its massive constituents have been constructed by means of constrained and random cosmological simulations. Two priors are assumed - the Λ cold dark matter model that is used to set up the simulations, and an LG model that encodes the observational knowledge of the LG and is used to select LG-like objects from the simulations. The constrained simulations are designed to reproduce the local cosmography as it is imprinted on to the Cosmicflows-2 data base of velocities. Several prescriptions are used to define the LG model, focusing in particular on different recent estimates of the tangential velocity of M31. It is found that (a) different vtan choices affect the peak mass values up to a factor of 2, and change mass ratios of MM31 to MMW by up to 20 per cent; (b) constrained simulations yield more sharply peaked posterior distributions compared with the random ones; (c) LG mass estimates are found to be smaller than those found using the timing argument; (d) preferred Milky Way masses lie in the range of (0.6-0.8) × 1012 M⊙; whereas (e) MM31 is found to vary between (1.0-2.0) × 1012 M⊙, with a strong dependence on the vtan values used.

  12. Fully Printed Flexible and Stretchable Electronics

    Science.gov (United States)

    Zhang, Suoming

    Through this thesis proposal, the author has demonstrated series of flexible or stretchable sensors including strain gauge, pressure sensors, display arrays, thin film transistors and photodetectors fabricated by a direct printing process. By adopting the novel serpentine configuration with conventional non-stretchable materials silver nanoparticles, the fully printed stretchable devices are successfully fabricated on elastomeric substrate with the demonstration of stretchable conductors that can maintain the electrical properties under strain and the strain gauge, which could be used to measure the strain in desired locations and also to monitor individual person's finger motion. And by investigating the intrinsic stretchable materials silver nanowires (AgNWs) with the conventional configuration, the fully printed stretchable conductors are achieved on various substrates including Si, glass, Polyimide, Polydimethylsiloxane (PDMS) and Very High Bond (VHB) tape with the illustration of the capacitive pressure sensor and stretchable electroluminescent displays. In addition, intrinsically stretchable thin-film transistors (TFTs) and integrated logic circuits are directly printed on elastomeric PDMS substrates. The printed devices utilize carbon nanotubes and a type of hybrid gate dielectric comprising PDMS and barium titanate (BaTiO3) nanoparticles. The BaTiO3/PDMS composite simultaneously provides high dielectric constant, superior stretchability, low leakage, as well as good printability and compatibility with the elastomeric substrate. Both TFTs and logic circuits can be stretched beyond 50% strain along either channel length or channel width directions for thousands of cycles while showing no significant degradation in electrical performance. Finally, by applying the SWNTs as the channel layer of the thin film transistor, we successfully fabricate the fully printed flexible photodetector which exhibits good electrical characteristics and the transistors exhibit

  13. Elastic Model Transitions Using Quadratic Inequality Constrained Least Squares

    Science.gov (United States)

    Orr, Jeb S.

    2012-01-01

    A technique is presented for initializing multiple discrete finite element model (FEM) mode sets for certain types of flight dynamics formulations that rely on superposition of orthogonal modes for modeling the elastic response. Such approaches are commonly used for modeling launch vehicle dynamics, and challenges arise due to the rapidly time-varying nature of the rigid-body and elastic characteristics. By way of an energy argument, a quadratic inequality constrained least squares (LSQI) algorithm is employed to e ect a smooth transition from one set of FEM eigenvectors to another with no requirement that the models be of similar dimension or that the eigenvectors be correlated in any particular way. The physically unrealistic and controversial method of eigenvector interpolation is completely avoided, and the discrete solution approximates that of the continuously varying system. The real-time computational burden is shown to be negligible due to convenient features of the solution method. Simulation results are presented, and applications to staging and other discontinuous mass changes are discussed

  14. A field theory description of constrained energy-dissipation processes

    International Nuclear Information System (INIS)

    Mandzhavidze, I.D.; Sisakyan, A.N.

    2002-01-01

    A field theory description of dissipation processes constrained by a high-symmetry group is given. The formalism is presented in the example of the multiple-hadron production processes, where the transition to the thermodynamic equilibrium results from the kinetic energy of colliding particles dissipating into hadron masses. The dynamics of these processes is restricted because the constraints responsible for the colour charge confinement must be taken into account. We develop a more general S-matrix formulation of the thermodynamics of nonequilibrium dissipative processes and find a necessary and sufficient condition for the validity of this description; this condition is similar to the correlation relaxation condition, which, according to Bogolyubov, must apply as the system approaches equilibrium. This situation must physically occur in processes with an extremely high multiplicity, at least if the hadron mass is nonzero. We also describe a new strong-coupling perturbation scheme, which is useful for taking symmetry restrictions on the dynamics of dissipation processes into account. We review the literature devoted to this problem

  15. Sparse/Low Rank Constrained Reconstruction for Dynamic PET Imaging.

    Directory of Open Access Journals (Sweden)

    Xingjian Yu

    Full Text Available In dynamic Positron Emission Tomography (PET, an estimate of the radio activity concentration is obtained from a series of frames of sinogram data taken at ranging in duration from 10 seconds to minutes under some criteria. So far, all the well-known reconstruction algorithms require known data statistical properties. It limits the speed of data acquisition, besides, it is unable to afford the separated information about the structure and the variation of shape and rate of metabolism which play a major role in improving the visualization of contrast for some requirement of the diagnosing in application. This paper presents a novel low rank-based activity map reconstruction scheme from emission sinograms of dynamic PET, termed as SLCR representing Sparse/Low Rank Constrained Reconstruction for Dynamic PET Imaging. In this method, the stationary background is formulated as a low rank component while variations between successive frames are abstracted to the sparse. The resulting nuclear norm and l1 norm related minimization problem can also be efficiently solved by many recently developed numerical methods. In this paper, the linearized alternating direction method is applied. The effectiveness of the proposed scheme is illustrated on three data sets.

  16. Curcumin nanodisks: formulation and characterization

    OpenAIRE

    Ghosh, Mistuni; Singh, Amareshwar T. K.; Xu, Wenwei; Sulchek, Todd; Gordon, Leo I.; Ryan, Robert O.

    2010-01-01

    Nanodisks (ND) are nanoscale, disk-shaped phospholipid bilayers whose edge is stabilized by apolipoproteins. In the present study, ND were formulated with the bioactive polyphenol, curcumin, at a 6:1 phospholipid:curcumin molar ratio. Atomic force microscopy revealed that curcumin-ND are particles with diameters

  17. Covariant Formulation of Hooke's Law.

    Science.gov (United States)

    Gron, O.

    1981-01-01

    Introducing a four-vector strain and a four-force stress, Hooke's law is written as a four-vector equation. This formulation is shown to clarify seemingly paradoxical results in connection with uniformly accelerated motion, and rotational motion with angular acceleration. (Author/JN)

  18. Hamiltonian formulation of the supermembrane

    International Nuclear Information System (INIS)

    Bergshoeff, E.; Sezgin, E.; Tanii, Y.

    1987-06-01

    The Hamiltonian formulation of the supermembrane theory in eleven dimensions is given. The covariant split of the first and second class constraints is exhibited, and their Dirac brackets are computed. Gauge conditions are imposed in such a way that the reparametrizations of the membrane with divergence free 2-vectors are unfixed. (author). 10 refs

  19. A Fully Automated Penumbra Segmentation Tool

    DEFF Research Database (Denmark)

    Nagenthiraja, Kartheeban; Ribe, Lars Riisgaard; Hougaard, Kristina Dupont

    2012-01-01

    Introduction: Perfusion- and diffusion weighted MRI (PWI/DWI) is widely used to select patients who are likely to benefit from recanalization therapy. The visual identification of PWI-DWI-mismatch tissue depends strongly on the observer, prompting a need for software, which estimates potentially...... salavageable tissue, quickly and accurately. We present a fully Automated Penumbra Segmentation (APS) algorithm using PWI and DWI images. We compare automatically generated PWI-DWI mismatch mask to mask outlined manually by experts, in 168 patients. Method: The algorithm initially identifies PWI lesions......) at 600∙10-6 mm2/sec. Due to the nature of thresholding, the ADC mask overestimates the DWI lesion volume and consequently we initialized level-set algorithm on DWI image with ADC mask as prior knowledge. Combining the PWI and inverted DWI mask then yield the PWI-DWI mismatch mask. Four expert raters...

  20. Simulations of fully deformed oscillating flux tubes

    Science.gov (United States)

    Karampelas, K.; Van Doorsselaere, T.

    2018-02-01

    Context. In recent years, a number of numerical studies have been focusing on the significance of the Kelvin-Helmholtz instability in the dynamics of oscillating coronal loops. This process enhances the transfer of energy into smaller scales, and has been connected with heating of coronal loops, when dissipation mechanisms, such as resistivity, are considered. However, the turbulent layer is expected near the outer regions of the loops. Therefore, the effects of wave heating are expected to be confined to the loop's external layers, leaving their denser inner parts without a heating mechanism. Aim. In the current work we aim to study the spatial evolution of wave heating effects from a footpoint driven standing kink wave in a coronal loop. Methods: Using the MPI-AMRVAC code, we performed ideal, three dimensional magnetohydrodynamic simulations of footpoint driven transverse oscillations of a cold, straight coronal flux tube, embedded in a hotter environment. We have also constructed forward models for our simulation using the FoMo code. Results: The developed transverse wave induced Kelvin-Helmholtz (TWIKH) rolls expand throughout the tube cross-section, and cover it entirely. This turbulence significantly alters the initial density profile, leading to a fully deformed cross section. As a consequence, the resistive and viscous heating rate both increase over the entire loop cross section. The resistive heating rate takes its maximum values near the footpoints, while the viscous heating rate at the apex. Conclusions: We conclude that even a monoperiodic driver can spread wave heating over the whole loop cross section, potentially providing a heating source in the inner loop region. Despite the loop's fully deformed structure, forward modelling still shows the structure appearing as a loop. A movie attached to Fig. 1 is available at http://https://www.aanda.org

  1. Lidar Cloud Detection with Fully Convolutional Networks

    Science.gov (United States)

    Cromwell, E.; Flynn, D.

    2017-12-01

    The vertical distribution of clouds from active remote sensing instrumentation is a widely used data product from global atmospheric measuring sites. The presence of clouds can be expressed as a binary cloud mask and is a primary input for climate modeling efforts and cloud formation studies. Current cloud detection algorithms producing these masks do not accurately identify the cloud boundaries and tend to oversample or over-represent the cloud. This translates as uncertainty for assessing the radiative impact of clouds and tracking changes in cloud climatologies. The Atmospheric Radiation Measurement (ARM) program has over 20 years of micro-pulse lidar (MPL) and High Spectral Resolution Lidar (HSRL) instrument data and companion automated cloud mask product at the mid-latitude Southern Great Plains (SGP) and the polar North Slope of Alaska (NSA) atmospheric observatory. Using this data, we train a fully convolutional network (FCN) with semi-supervised learning to segment lidar imagery into geometric time-height cloud locations for the SGP site and MPL instrument. We then use transfer learning to train a FCN for (1) the MPL instrument at the NSA site and (2) for the HSRL. In our semi-supervised approach, we pre-train the classification layers of the FCN with weakly labeled lidar data. Then, we facilitate end-to-end unsupervised pre-training and transition to fully supervised learning with ground truth labeled data. Our goal is to improve the cloud mask accuracy and precision for the MPL instrument to 95% and 80%, respectively, compared to the current cloud mask algorithms of 89% and 50%. For the transfer learning based FCN for the HSRL instrument, our goal is to achieve a cloud mask accuracy of 90% and a precision of 80%.

  2. A novel fully integrated handheld gamma camera

    International Nuclear Information System (INIS)

    Massari, R.; Ucci, A.; Campisi, C.; Scopinaro, F.; Soluri, A.

    2016-01-01

    In this paper, we present an innovative, fully integrated handheld gamma camera, namely designed to gather in the same device the gamma ray detector with the display and the embedded computing system. The low power consumption allows the prototype to be battery operated. To be useful in radioguided surgery, an intraoperative gamma camera must be very easy to handle since it must be moved to find a suitable view. Consequently, we have developed the first prototype of a fully integrated, compact and lightweight gamma camera for radiopharmaceuticals fast imaging. The device can operate without cables across the sterile field, so it may be easily used in the operating theater for radioguided surgery. The prototype proposed consists of a Silicon Photomultiplier (SiPM) array coupled with a proprietary scintillation structure based on CsI(Tl) crystals. To read the SiPM output signals, we have developed a very low power readout electronics and a dedicated analog to digital conversion system. One of the most critical aspects we faced designing the prototype was the low power consumption, which is mandatory to develop a battery operated device. We have applied this detection device in the lymphoscintigraphy technique (sentinel lymph node mapping) comparing the results obtained with those of a commercial gamma camera (Philips SKYLight). The results obtained confirm a rapid response of the device and an adequate spatial resolution for the use in the scintigraphic imaging. This work confirms the feasibility of a small gamma camera with an integrated display. This device is designed for radioguided surgery and small organ imaging, but it could be easily combined into surgical navigation systems.

  3. A novel fully integrated handheld gamma camera

    Energy Technology Data Exchange (ETDEWEB)

    Massari, R.; Ucci, A.; Campisi, C. [Biostructure and Bioimaging Institute (IBB), National Research Council of Italy (CNR), Rome (Italy); Scopinaro, F. [University of Rome “La Sapienza”, S. Andrea Hospital, Rome (Italy); Soluri, A., E-mail: alessandro.soluri@ibb.cnr.it [Biostructure and Bioimaging Institute (IBB), National Research Council of Italy (CNR), Rome (Italy)

    2016-10-01

    In this paper, we present an innovative, fully integrated handheld gamma camera, namely designed to gather in the same device the gamma ray detector with the display and the embedded computing system. The low power consumption allows the prototype to be battery operated. To be useful in radioguided surgery, an intraoperative gamma camera must be very easy to handle since it must be moved to find a suitable view. Consequently, we have developed the first prototype of a fully integrated, compact and lightweight gamma camera for radiopharmaceuticals fast imaging. The device can operate without cables across the sterile field, so it may be easily used in the operating theater for radioguided surgery. The prototype proposed consists of a Silicon Photomultiplier (SiPM) array coupled with a proprietary scintillation structure based on CsI(Tl) crystals. To read the SiPM output signals, we have developed a very low power readout electronics and a dedicated analog to digital conversion system. One of the most critical aspects we faced designing the prototype was the low power consumption, which is mandatory to develop a battery operated device. We have applied this detection device in the lymphoscintigraphy technique (sentinel lymph node mapping) comparing the results obtained with those of a commercial gamma camera (Philips SKYLight). The results obtained confirm a rapid response of the device and an adequate spatial resolution for the use in the scintigraphic imaging. This work confirms the feasibility of a small gamma camera with an integrated display. This device is designed for radioguided surgery and small organ imaging, but it could be easily combined into surgical navigation systems.

  4. Chance-constrained programming approach to natural-gas curtailment decisions

    Energy Technology Data Exchange (ETDEWEB)

    Guldmann, J M

    1981-10-01

    This paper presents a modeling methodology for the determination of optimal-curtailment decisions by a gas-distribution utility during a chronic gas-shortage situation. Based on the end-use priority approach, a linear-programming model is formulated, that reallocates the available gas supply among the utility's customers while minimizing fuel switching, unemployment, and utility operating costs. This model is then transformed into a chance-constrained program in order to account for the weather-related variability of the gas requirements. The methodology is applied to the East Ohio Gas Company. 16 references, 2 figures, 3 tables.

  5. Event-triggered decentralized robust model predictive control for constrained large-scale interconnected systems

    Directory of Open Access Journals (Sweden)

    Ling Lu

    2016-12-01

    Full Text Available This paper considers the problem of event-triggered decentralized model predictive control (MPC for constrained large-scale linear systems subject to additive bounded disturbances. The constraint tightening method is utilized to formulate the MPC optimization problem. The local predictive control law for each subsystem is determined aperiodically by relevant triggering rule which allows a considerable reduction of the computational load. And then, the robust feasibility and closed-loop stability are proved and it is shown that every subsystem state will be driven into a robust invariant set. Finally, the effectiveness of the proposed approach is illustrated via numerical simulations.

  6. CONSTRAINED-TRANSPORT MAGNETOHYDRODYNAMICS WITH ADAPTIVE MESH REFINEMENT IN CHARM

    International Nuclear Information System (INIS)

    Miniati, Francesco; Martin, Daniel F.

    2011-01-01

    We present the implementation of a three-dimensional, second-order accurate Godunov-type algorithm for magnetohydrodynamics (MHD) in the adaptive-mesh-refinement (AMR) cosmological code CHARM. The algorithm is based on the full 12-solve spatially unsplit corner-transport-upwind (CTU) scheme. The fluid quantities are cell-centered and are updated using the piecewise-parabolic method (PPM), while the magnetic field variables are face-centered and are evolved through application of the Stokes theorem on cell edges via a constrained-transport (CT) method. The so-called multidimensional MHD source terms required in the predictor step for high-order accuracy are applied in a simplified form which reduces their complexity in three dimensions without loss of accuracy or robustness. The algorithm is implemented on an AMR framework which requires specific synchronization steps across refinement levels. These include face-centered restriction and prolongation operations and a reflux-curl operation, which maintains a solenoidal magnetic field across refinement boundaries. The code is tested against a large suite of test problems, including convergence tests in smooth flows, shock-tube tests, classical two- and three-dimensional MHD tests, a three-dimensional shock-cloud interaction problem, and the formation of a cluster of galaxies in a fully cosmological context. The magnetic field divergence is shown to remain negligible throughout.

  7. Cascading Constrained 2-D Arrays using Periodic Merging Arrays

    DEFF Research Database (Denmark)

    Forchhammer, Søren; Laursen, Torben Vaarby

    2003-01-01

    We consider a method for designing 2-D constrained codes by cascading finite width arrays using predefined finite width periodic merging arrays. This provides a constructive lower bound on the capacity of the 2-D constrained code. Examples include symmetric RLL and density constrained codes...

  8. Operator approach to solutions of the constrained BKP hierarchy

    International Nuclear Information System (INIS)

    Shen, Hsin-Fu; Lee, Niann-Chern; Tu, Ming-Hsien

    2011-01-01

    The operator formalism to the vector k-constrained BKP hierarchy is presented. We solve the Hirota bilinear equations of the vector k-constrained BKP hierarchy via the method of neutral free fermion. In particular, by choosing suitable group element of O(∞), we construct rational and soliton solutions of the vector k-constrained BKP hierarchy.

  9. Fully Device-Independent Quantum Key Distribution

    Science.gov (United States)

    Vazirani, Umesh; Vidick, Thomas

    2014-10-01

    Quantum cryptography promises levels of security that are impossible to replicate in a classical world. Can this security be guaranteed even when the quantum devices on which the protocol relies are untrusted? This central question dates back to the early 1990s when the challenge of achieving device-independent quantum key distribution was first formulated. We answer this challenge by rigorously proving the device-independent security of a slight variant of Ekert's original entanglement-based protocol against the most general (coherent) attacks. The resulting protocol is robust: While assuming only that the devices can be modeled by the laws of quantum mechanics and are spatially isolated from each other and from any adversary's laboratory, it achieves a linear key rate and tolerates a constant noise rate in the devices. In particular, the devices may have quantum memory and share arbitrary quantum correlations with the eavesdropper. The proof of security is based on a new quantitative understanding of the monogamous nature of quantum correlations in the context of a multiparty protocol.

  10. Engineering aspects of a fully mirrored endoscope

    International Nuclear Information System (INIS)

    Terra, A.; Huber, A.; Schweer, B.; Mertens, Ph.; Arnoux, G.; Balshaw, N.; Brezinsek, S.; Egner, S.; Hartl, M.; Kampf, D.; Klammer, J.; Lambertz, H.T.; Morlock, C.; Murari, A.; Reindl, M.; Sanders, S.; Sergienko, G.; Spencer, G.

    2013-01-01

    Highlights: ► Replacement of JET diagnostics to match the new ITER-like Wall. ► The endoscope test ITER-like design with only mirror based optics. ► Withstanding and diagnostic capability during Plasma operation and disruptions. ► Engineering process from design to installation and procurement. -- Abstract: The development of optical diagnostics, like endoscopes, compatible with the ITER environment (metallic plasma facing components, neutron proof optics, etc.) is a challenge, but current tokamaks such as JET provide opportunities to test fully working concepts. This paper describes the engineering aspects of a fully mirrored endoscope that has recently been designed, procured and installed on JET. The system must operate in a very strict environment with high temperature, high magnetic fields up to B = 4 T and rapid field variations (∂B/∂t ∼ 100 T/s) that induce high stresses due to eddy currents in the front mirror assembly. It must be designed to withstand high mechanical loads especially during disruptions, which lead to acceleration of about 7 g at 14 Hz. For the JET endoscope, when the plasma thermal loading, direct and indirect, was added to the assumed disruption loads, the reserve factor, defined as a ratio of yield strength over summed up von Mises stresses, was close to 1 for the mirror components. To ensure reliable operation, several analyses were performed to evaluate the thermo-mechanical performance of the endoscope and a final validation was obtained from mechanical and thermal tests, before the system's final installation in May 2011. During the tests, stability of the field of view angle variation was kept below 1° despite the high thermal gradient on endoscope head (∂T/∂x ∼ 500 K/m). In parallel, to ensure long time operation and to prevent undesirable performance degradation, a shutter system was also implemented in order to reduce impurity deposition on in-vessel mirrors but also to allow in situ transmission calibration

  11. Fully 3D refraction correction dosimetry system

    International Nuclear Information System (INIS)

    Manjappa, Rakesh; Makki, S Sharath; Kanhirodan, Rajan; Kumar, Rajesh; Vasu, Ram Mohan

    2016-01-01

    The irradiation of selective regions in a polymer gel dosimeter results in an increase in optical density and refractive index (RI) at those regions. An optical tomography-based dosimeter depends on rayline path through the dosimeter to estimate and reconstruct the dose distribution. The refraction of light passing through a dose region results in artefacts in the reconstructed images. These refraction errors are dependant on the scanning geometry and collection optics. We developed a fully 3D image reconstruction algorithm, algebraic reconstruction technique-refraction correction (ART-rc) that corrects for the refractive index mismatches present in a gel dosimeter scanner not only at the boundary, but also for any rayline refraction due to multiple dose regions inside the dosimeter. In this study, simulation and experimental studies have been carried out to reconstruct a 3D dose volume using 2D CCD measurements taken for various views. The study also focuses on the effectiveness of using different refractive-index matching media surrounding the gel dosimeter. Since the optical density is assumed to be low for a dosimeter, the filtered backprojection is routinely used for reconstruction. We carry out the reconstructions using conventional algebraic reconstruction (ART) and refractive index corrected ART (ART-rc) algorithms. The reconstructions based on FDK algorithm for cone-beam tomography has also been carried out for comparison. Line scanners and point detectors, are used to obtain reconstructions plane by plane. The rays passing through dose region with a RI mismatch does not reach the detector in the same plane depending on the angle of incidence and RI. In the fully 3D scanning setup using 2D array detectors, light rays that undergo refraction are still collected and hence can still be accounted for in the reconstruction algorithm. It is found that, for the central region of the dosimeter, the usable radius using ART-rc algorithm with water as RI matched

  12. Fully 3D refraction correction dosimetry system.

    Science.gov (United States)

    Manjappa, Rakesh; Makki, S Sharath; Kumar, Rajesh; Vasu, Ram Mohan; Kanhirodan, Rajan

    2016-02-21

    The irradiation of selective regions in a polymer gel dosimeter results in an increase in optical density and refractive index (RI) at those regions. An optical tomography-based dosimeter depends on rayline path through the dosimeter to estimate and reconstruct the dose distribution. The refraction of light passing through a dose region results in artefacts in the reconstructed images. These refraction errors are dependant on the scanning geometry and collection optics. We developed a fully 3D image reconstruction algorithm, algebraic reconstruction technique-refraction correction (ART-rc) that corrects for the refractive index mismatches present in a gel dosimeter scanner not only at the boundary, but also for any rayline refraction due to multiple dose regions inside the dosimeter. In this study, simulation and experimental studies have been carried out to reconstruct a 3D dose volume using 2D CCD measurements taken for various views. The study also focuses on the effectiveness of using different refractive-index matching media surrounding the gel dosimeter. Since the optical density is assumed to be low for a dosimeter, the filtered backprojection is routinely used for reconstruction. We carry out the reconstructions using conventional algebraic reconstruction (ART) and refractive index corrected ART (ART-rc) algorithms. The reconstructions based on FDK algorithm for cone-beam tomography has also been carried out for comparison. Line scanners and point detectors, are used to obtain reconstructions plane by plane. The rays passing through dose region with a RI mismatch does not reach the detector in the same plane depending on the angle of incidence and RI. In the fully 3D scanning setup using 2D array detectors, light rays that undergo refraction are still collected and hence can still be accounted for in the reconstruction algorithm. It is found that, for the central region of the dosimeter, the usable radius using ART-rc algorithm with water as RI matched

  13. Langevin formulation of quantum dynamics

    International Nuclear Information System (INIS)

    Roncadelli, M.

    1989-03-01

    We first show that nonrelativistic quantum mechanics formulated at imaginary-(h/2 π) can formally be viewed as the Fokker-Planck description of a frictionless brownian motion, which occurs (in general) in an absorbing medium. We next offer a new formulation of quantum mechanics, which is basically the Langevin treatment of this brownian motion. Explicitly, we derive a noise-average representation for the transition probability W(X'',t''|X',t'), in terms of the solutions to a Langevin equation with a Gaussian white-noise. Upon analytic continuation back to real-(h/2 π),W(X'',t''|X',t') becomes the propagator of the original Schroedinger equation. Our approach allows for a straightforward application to quantum dynamical problems of the mathematical techniques of classical stochastic processes. Moreover, computer simulations of quantum mechanical systems can be carried out by using numerical programs based on the Langevin dynamics. (author). 19 refs, 1 tab

  14. Constrained optimization of test intervals using a steady-state genetic algorithm

    International Nuclear Information System (INIS)

    Martorell, S.; Carlos, S.; Sanchez, A.; Serradell, V.

    2000-01-01

    There is a growing interest from both the regulatory authorities and the nuclear industry to stimulate the use of Probabilistic Risk Analysis (PRA) for risk-informed applications at Nuclear Power Plants (NPPs). Nowadays, special attention is being paid on analyzing plant-specific changes to Test Intervals (TIs) within the Technical Specifications (TSs) of NPPs and it seems to be a consensus on the need of making these requirements more risk-effective and less costly. Resource versus risk-control effectiveness principles formally enters in optimization problems. This paper presents an approach for using the PRA models in conducting the constrained optimization of TIs based on a steady-state genetic algorithm (SSGA) where the cost or the burden is to be minimized while the risk or performance is constrained to be at a given level, or vice versa. The paper encompasses first with the problem formulation, where the objective function and constraints that apply in the constrained optimization of TIs based on risk and cost models at system level are derived. Next, the foundation of the optimizer is given, which is derived by customizing a SSGA in order to allow optimizing TIs under constraints. Also, a case study is performed using this approach, which shows the benefits of adopting both PRA models and genetic algorithms, in particular for the constrained optimization of TIs, although it is also expected a great benefit of using this approach to solve other engineering optimization problems. However, care must be taken in using genetic algorithms in constrained optimization problems as it is concluded in this paper

  15. Feature and Pose Constrained Visual Aided Inertial Navigation for Computationally Constrained Aerial Vehicles

    Science.gov (United States)

    Williams, Brian; Hudson, Nicolas; Tweddle, Brent; Brockers, Roland; Matthies, Larry

    2011-01-01

    A Feature and Pose Constrained Extended Kalman Filter (FPC-EKF) is developed for highly dynamic computationally constrained micro aerial vehicles. Vehicle localization is achieved using only a low performance inertial measurement unit and a single camera. The FPC-EKF framework augments the vehicle's state with both previous vehicle poses and critical environmental features, including vertical edges. This filter framework efficiently incorporates measurements from hundreds of opportunistic visual features to constrain the motion estimate, while allowing navigating and sustained tracking with respect to a few persistent features. In addition, vertical features in the environment are opportunistically used to provide global attitude references. Accurate pose estimation is demonstrated on a sequence including fast traversing, where visual features enter and exit the field-of-view quickly, as well as hover and ingress maneuvers where drift free navigation is achieved with respect to the environment.

  16. Optimization of chlorphenesin emulgel formulation

    OpenAIRE

    Mohamed, Magdy I.

    2004-01-01

    This study was conducted to develop an emulgel formulation of chlorphenesin (CHL) using 2 types of gelling agents: hydroxypropylmethyl cellulose (HPMC) and Carbopol 934. The influence of the type of the gelling agent and the concentration of both the oil phase and emulsifying agent on the drug release from the prepared emulgels was investigated using a 23 factorial design. The prepared emulgels were evaluated for their physical appearance, rheological behavior, drug release, antifungal activi...

  17. Incomplete Dirac reduction of constrained Hamiltonian systems

    Energy Technology Data Exchange (ETDEWEB)

    Chandre, C., E-mail: chandre@cpt.univ-mrs.fr

    2015-10-15

    First-class constraints constitute a potential obstacle to the computation of a Poisson bracket in Dirac’s theory of constrained Hamiltonian systems. Using the pseudoinverse instead of the inverse of the matrix defined by the Poisson brackets between the constraints, we show that a Dirac–Poisson bracket can be constructed, even if it corresponds to an incomplete reduction of the original Hamiltonian system. The uniqueness of Dirac brackets is discussed. The relevance of this procedure for infinite dimensional Hamiltonian systems is exemplified.

  18. Capturing Hotspots For Constrained Indoor Movement

    DEFF Research Database (Denmark)

    Ahmed, Tanvir; Pedersen, Torben Bach; Lu, Hua

    2013-01-01

    Finding the hotspots in large indoor spaces is very important for getting overloaded locations, security, crowd management, indoor navigation and guidance. The tracking data coming from indoor tracking are huge in volume and not readily available for finding hotspots. This paper presents a graph......-based model for constrained indoor movement that can map the tracking records into mapping records which represent the entry and exit times of an object in a particular location. Then it discusses the hotspots extraction technique from the mapping records....

  19. Quantization of soluble classical constrained systems

    International Nuclear Information System (INIS)

    Belhadi, Z.; Menas, F.; Bérard, A.; Mohrbach, H.

    2014-01-01

    The derivation of the brackets among coordinates and momenta for classical constrained systems is a necessary step toward their quantization. Here we present a new approach for the determination of the classical brackets which does neither require Dirac’s formalism nor the symplectic method of Faddeev and Jackiw. This approach is based on the computation of the brackets between the constants of integration of the exact solutions of the equations of motion. From them all brackets of the dynamical variables of the system can be deduced in a straightforward way

  20. Quantization of soluble classical constrained systems

    Energy Technology Data Exchange (ETDEWEB)

    Belhadi, Z. [Laboratoire de physique et chimie quantique, Faculté des sciences, Université Mouloud Mammeri, BP 17, 15000 Tizi Ouzou (Algeria); Laboratoire de physique théorique, Faculté des sciences exactes, Université de Bejaia, 06000 Bejaia (Algeria); Menas, F. [Laboratoire de physique et chimie quantique, Faculté des sciences, Université Mouloud Mammeri, BP 17, 15000 Tizi Ouzou (Algeria); Ecole Nationale Préparatoire aux Etudes d’ingéniorat, Laboratoire de physique, RN 5 Rouiba, Alger (Algeria); Bérard, A. [Equipe BioPhysStat, Laboratoire LCP-A2MC, ICPMB, IF CNRS No 2843, Université de Lorraine, 1 Bd Arago, 57078 Metz Cedex (France); Mohrbach, H., E-mail: herve.mohrbach@univ-lorraine.fr [Equipe BioPhysStat, Laboratoire LCP-A2MC, ICPMB, IF CNRS No 2843, Université de Lorraine, 1 Bd Arago, 57078 Metz Cedex (France)

    2014-12-15

    The derivation of the brackets among coordinates and momenta for classical constrained systems is a necessary step toward their quantization. Here we present a new approach for the determination of the classical brackets which does neither require Dirac’s formalism nor the symplectic method of Faddeev and Jackiw. This approach is based on the computation of the brackets between the constants of integration of the exact solutions of the equations of motion. From them all brackets of the dynamical variables of the system can be deduced in a straightforward way.

  1. PVT Panels. Fully renewable and competitive

    International Nuclear Information System (INIS)

    Bakker, M.; Strootman, K.J.; Jong, M.J.M.

    2003-10-01

    A photovoltaic/thermal (PVT) panel is a combination of photovoltaic cells with a solar thermal collector, generating solar electricity and solar heat simultaneously. PVT panels generate more solar energy per unit surface area than a combination of separate PV panels and solar thermal collectors, and share the aesthetic advantage of PV. After several years of research, PVT panels have been developed into a product that is now ready for market introduction. One of the most promising system concepts, consisting of 25 m 2 of PVT panels and a ground coupled heat pump, has been simulated in TRNSYS, and has been found to be able to fully cover both the building related electricity and heat consumption, while keeping the long-term average ground temperature constant. The cost and payback time of such a system have been determined; it has been found that the payback time of this system is approximately two-thirds of the payback time of an identical system but with 21 m 2 of PV panels and 4 m 2 of solar thermal collectors. Finally, by looking at the expected growth in the PV and solar thermal collector market, the market potential for for PVT panels has been found to be very large

  2. A new fully automated TLD badge reader

    International Nuclear Information System (INIS)

    Kannan, S.; Ratna, P.; Kulkarni, M.S.

    2003-01-01

    At present personnel monitoring in India is being carried out using a number of manual and semiautomatic TLD badge Readers and the BARC TL dosimeter badge designed during 1970. Of late the manual TLD badge readers are almost completely replaced by semiautomatic readers with a number of performance improvements like use of hot gas heating to reduce the readout time considerably. PC based design with storage of glow curve for every dosimeter, on-line dose computation and printout of dose reports, etc. However the semiautomatic system suffers from the lack of a machine readable ID code on the badge and the physical design of the dosimeter card not readily compatible for automation. This paper describes a fully automated TLD badge Reader developed in the RSS Division, using a new TLD badge with machine readable ID code. The new PC based reader has a built-in reader for reading the ID code, in the form of an array of holes, on the dosimeter card. The reader has a number of self-diagnostic features to ensure a high degree of reliability. (author)

  3. Fully inkjet-printed microwave passive electronics

    KAUST Repository

    McKerricher, Garret

    2017-01-30

    Fully inkjet-printed three-dimensional (3D) objects with integrated metal provide exciting possibilities for on-demand fabrication of radio frequency electronics such as inductors, capacitors, and filters. To date, there have been several reports of printed radio frequency components metallized via the use of plating solutions, sputtering, and low-conductivity pastes. These metallization techniques require rather complex fabrication, and do not provide an easily integrated or versatile process. This work utilizes a novel silver ink cured with a low-cost infrared lamp at only 80 °C, and achieves a high conductivity of 1×107 S m−1. By inkjet printing the infrared-cured silver together with a commercial 3D inkjet ultraviolet-cured acrylic dielectric, a multilayer process is demonstrated. By using a smoothing technique, both the conductive ink and dielectric provide surface roughness values of <500 nm. A radio frequency inductor and capacitor exhibit state-of-the-art quality factors of 8 and 20, respectively, and match well with electromagnetic simulations. These components are implemented in a lumped element radio frequency filter with an impressive insertion loss of 0.8 dB at 1 GHz, proving the utility of the process for sensitive radio frequency applications.

  4. The first LHC sector is fully interconnected

    CERN Multimedia

    2006-01-01

    Sector 7-8 is the first sector of the LHC to become fully operational. All the magnets, cryogenic line, vacuum chambers and services are interconnected. The cool down of this sector can soon commence. LHC project leader Lyn Evans, the teams from CERN's AT/MCS, AT/VAC and AT/MEL groups, and the members of the IEG consortium celebrate the completion of the first LHC sector. The 10th of November was a red letter day for the LHC accelerator teams, marking the completion of the first sector of the machine. The magnets of sector 7-8, together with the cryogenic line, the vacuum chambers and the distribution feedboxes (DFBs) are now all completely interconnected. Sector 7-8 has thus been closed and is the first LHC sector to become operational. The interconnection work required several thousand electrical, cryogenic and insulating connections to be made on the 210 interfaces between the magnets in the arc, the 30 interfaces between the special magnets and the interfaces with the cryogenic line. 'This represent...

  5. Fully Resolved Simulations of 3D Printing

    Science.gov (United States)

    Tryggvason, Gretar; Xia, Huanxiong; Lu, Jiacai

    2017-11-01

    Numerical simulations of Fused Deposition Modeling (FDM) (or Fused Filament Fabrication) where a filament of hot, viscous polymer is deposited to ``print'' a three-dimensional object, layer by layer, are presented. A finite volume/front tracking method is used to follow the injection, cooling, solidification and shrinking of the filament. The injection of the hot melt is modeled using a volume source, combined with a nozzle, modeled as an immersed boundary, that follows a prescribed trajectory. The viscosity of the melt depends on the temperature and the shear rate and the polymer becomes immobile as its viscosity increases. As the polymer solidifies, the stress is found by assuming a hyperelastic constitutive equation. The method is described and its accuracy and convergence properties are tested by grid refinement studies for a simple setup involving two short filaments, one on top of the other. The effect of the various injection parameters, such as nozzle velocity and injection velocity are briefly examined and the applicability of the approach to simulate the construction of simple multilayer objects is shown. The role of fully resolved simulations for additive manufacturing and their use for novel processes and as the ``ground truth'' for reduced order models is discussed.

  6. A fully implantable rodent neural stimulator

    Science.gov (United States)

    Perry, D. W. J.; Grayden, D. B.; Shepherd, R. K.; Fallon, J. B.

    2012-02-01

    The ability to electrically stimulate neural and other excitable tissues in behaving experimental animals is invaluable for both the development of neural prostheses and basic neurological research. We developed a fully implantable neural stimulator that is able to deliver two channels of intra-cochlear electrical stimulation in the rat. It is powered via a novel omni-directional inductive link and includes an on-board microcontroller with integrated radio link, programmable current sources and switching circuitry to generate charge-balanced biphasic stimulation. We tested the implant in vivo and were able to elicit both neural and behavioural responses. The implants continued to function for up to five months in vivo. While targeted to cochlear stimulation, with appropriate electrode arrays the stimulator is well suited to stimulating other neurons within the peripheral or central nervous systems. Moreover, it includes significant on-board data acquisition and processing capabilities, which could potentially make it a useful platform for telemetry applications, where there is a need to chronically monitor physiological variables in unrestrained animals.

  7. Microaneurysm detection using fully convolutional neural networks.

    Science.gov (United States)

    Chudzik, Piotr; Majumdar, Somshubra; Calivá, Francesco; Al-Diri, Bashir; Hunter, Andrew

    2018-05-01

    Diabetic retinopathy is a microvascular complication of diabetes that can lead to sight loss if treated not early enough. Microaneurysms are the earliest clinical signs of diabetic retinopathy. This paper presents an automatic method for detecting microaneurysms in fundus photographies. A novel patch-based fully convolutional neural network with batch normalization layers and Dice loss function is proposed. Compared to other methods that require up to five processing stages, it requires only three. Furthermore, to the best of the authors' knowledge, this is the first paper that shows how to successfully transfer knowledge between datasets in the microaneurysm detection domain. The proposed method was evaluated using three publicly available and widely used datasets: E-Ophtha, DIARETDB1, and ROC. It achieved better results than state-of-the-art methods using the FROC metric. The proposed algorithm accomplished highest sensitivities for low false positive rates, which is particularly important for screening purposes. Performance, simplicity, and robustness of the proposed method demonstrates its suitability for diabetic retinopathy screening applications. Copyright © 2018 Elsevier B.V. All rights reserved.

  8. Fully inkjet-printed microwave passive electronics

    KAUST Repository

    McKerricher, Garret; Vaseem, Mohammad; Shamim, Atif

    2017-01-01

    Fully inkjet-printed three-dimensional (3D) objects with integrated metal provide exciting possibilities for on-demand fabrication of radio frequency electronics such as inductors, capacitors, and filters. To date, there have been several reports of printed radio frequency components metallized via the use of plating solutions, sputtering, and low-conductivity pastes. These metallization techniques require rather complex fabrication, and do not provide an easily integrated or versatile process. This work utilizes a novel silver ink cured with a low-cost infrared lamp at only 80 °C, and achieves a high conductivity of 1×107 S m−1. By inkjet printing the infrared-cured silver together with a commercial 3D inkjet ultraviolet-cured acrylic dielectric, a multilayer process is demonstrated. By using a smoothing technique, both the conductive ink and dielectric provide surface roughness values of <500 nm. A radio frequency inductor and capacitor exhibit state-of-the-art quality factors of 8 and 20, respectively, and match well with electromagnetic simulations. These components are implemented in a lumped element radio frequency filter with an impressive insertion loss of 0.8 dB at 1 GHz, proving the utility of the process for sensitive radio frequency applications.

  9. Gyrokinetic energy conservation and Poisson-bracket formulation

    International Nuclear Information System (INIS)

    Brizard, A.

    1989-01-01

    An integral expression for the gyrokinetic total energy of a magnetized plasma, with general magnetic field configuration perturbed by fully electromagnetic fields, was recently derived through the use of a gyrocenter Lie transformation. It is shown that the gyrokinetic energy is conserved by the gyrokinetic Hamiltonian flow to all orders in perturbed fields. An explicit demonstration that a gyrokinetic Hamiltonian containing quadratic nonlinearities preserves the gyrokinetic energy up to third order is given. The Poisson-bracket formulation greatly facilitates this demonstration with the help of the Jacobi identity and other properties of the Poisson brackets

  10. Fully Coupled Simulation of Lithium Ion Battery Cell Performance

    Energy Technology Data Exchange (ETDEWEB)

    Trembacki, Bradley L. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Murthy, Jayathi Y. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Roberts, Scott Alan [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2015-09-01

    Lithium-ion battery particle-scale (non-porous electrode) simulations applied to resolved electrode geometries predict localized phenomena and can lead to better informed decisions on electrode design and manufacturing. This work develops and implements a fully-coupled finite volume methodology for the simulation of the electrochemical equations in a lithium-ion battery cell. The model implementation is used to investigate 3D battery electrode architectures that offer potential energy density and power density improvements over traditional layer-by-layer particle bed battery geometries. Advancement of micro-scale additive manufacturing techniques has made it possible to fabricate these 3D electrode microarchitectures. A variety of 3D battery electrode geometries are simulated and compared across various battery discharge rates and length scales in order to quantify performance trends and investigate geometrical factors that improve battery performance. The energy density and power density of the 3D battery microstructures are compared in several ways, including a uniform surface area to volume ratio comparison as well as a comparison requiring a minimum manufacturable feature size. Significant performance improvements over traditional particle bed electrode designs are observed, and electrode microarchitectures derived from minimal surfaces are shown to be superior. A reduced-order volume-averaged porous electrode theory formulation for these unique 3D batteries is also developed, allowing simulations on the full-battery scale. Electrode concentration gradients are modeled using the diffusion length method, and results for plate and cylinder electrode geometries are compared to particle-scale simulation results. Additionally, effective diffusion lengths that minimize error with respect to particle-scale results for gyroid and Schwarz P electrode microstructures are determined.

  11. A conservative fully implicit algorithm for predicting slug flows

    Science.gov (United States)

    Krasnopolsky, Boris I.; Lukyanov, Alexander A.

    2018-02-01

    An accurate and predictive modelling of slug flows is required by many industries (e.g., oil and gas, nuclear engineering, chemical engineering) to prevent undesired events potentially leading to serious environmental accidents. For example, the hydrodynamic and terrain-induced slugging leads to unwanted unsteady flow conditions. This demands the development of fast and robust numerical techniques for predicting slug flows. The presented in this paper study proposes a multi-fluid model and its implementation method accounting for phase appearance and disappearance. The numerical modelling of phase appearance and disappearance presents a complex numerical challenge for all multi-component and multi-fluid models. Numerical challenges arise from the singular systems of equations when some phases are absent and from the solution discontinuity when some phases appear or disappear. This paper provides a flexible and robust solution to these issues. A fully implicit formulation described in this work enables to efficiently solve governing fluid flow equations. The proposed numerical method provides a modelling capability of phase appearance and disappearance processes, which is based on switching procedure between various sets of governing equations. These sets of equations are constructed using information about the number of phases present in the computational domain. The proposed scheme does not require an explicit truncation of solutions leading to a conservative scheme for mass and linear momentum. A transient two-fluid model is used to verify and validate the proposed algorithm for conditions of hydrodynamic and terrain-induced slug flow regimes. The developed modelling capabilities allow to predict all the major features of the experimental data, and are in a good quantitative agreement with them.

  12. A Lean Framework for Production Control in Complex and Constrained Construction Projects (PC4P)

    DEFF Research Database (Denmark)

    Lindhard, Søren Munch; Wandahl, Søren

    2014-01-01

    Production conditions in construction are different than in themanufacturing industry. First of all, construction is rooted in place and conducted as on-site manufacturing. Secondly, every construction project is unique and a one-of-a-kind production, managed by a temporary organization consisting...... and constrained construction project. Even though several tools have attempted to add structure and to create order, to the complex, dynamic, and uncertain context in which constructions is conducted, none has yet fully succeeded in providing a robust production control system. With outset in the lean tool Last...

  13. An L∞/L1-Constrained Quadratic Optimization Problem with Applications to Neural Networks

    International Nuclear Information System (INIS)

    Leizarowitz, Arie; Rubinstein, Jacob

    2003-01-01

    Pattern formation in associative neural networks is related to a quadratic optimization problem. Biological considerations imply that the functional is constrained in the L ∞ norm and in the L 1 norm. We consider such optimization problems. We derive the Euler-Lagrange equations, and construct basic properties of the maximizers. We study in some detail the case where the kernel of the quadratic functional is finite-dimensional. In this case the optimization problem can be fully characterized by the geometry of a certain convex and compact finite-dimensional set

  14. Fringe instability in constrained soft elastic layers.

    Science.gov (United States)

    Lin, Shaoting; Cohen, Tal; Zhang, Teng; Yuk, Hyunwoo; Abeyaratne, Rohan; Zhao, Xuanhe

    2016-11-04

    Soft elastic layers with top and bottom surfaces adhered to rigid bodies are abundant in biological organisms and engineering applications. As the rigid bodies are pulled apart, the stressed layer can exhibit various modes of mechanical instabilities. In cases where the layer's thickness is much smaller than its length and width, the dominant modes that have been studied are the cavitation, interfacial and fingering instabilities. Here we report a new mode of instability which emerges if the thickness of the constrained elastic layer is comparable to or smaller than its width. In this case, the middle portion along the layer's thickness elongates nearly uniformly while the constrained fringe portions of the layer deform nonuniformly. When the applied stretch reaches a critical value, the exposed free surfaces of the fringe portions begin to undulate periodically without debonding from the rigid bodies, giving the fringe instability. We use experiments, theory and numerical simulations to quantitatively explain the fringe instability and derive scaling laws for its critical stress, critical strain and wavelength. We show that in a force controlled setting the elastic fingering instability is associated with a snap-through buckling that does not exist for the fringe instability. The discovery of the fringe instability will not only advance the understanding of mechanical instabilities in soft materials but also have implications for biological and engineered adhesives and joints.

  15. Topology Optimization of Constrained Layer Damping on Plates Using Method of Moving Asymptote (MMA Approach

    Directory of Open Access Journals (Sweden)

    Zheng Ling

    2011-01-01

    Full Text Available Damping treatments have been extensively used as a powerful means to damp out structural resonant vibrations. Usually, damping materials are fully covered on the surface of plates. The drawbacks of this conventional treatment are also obvious due to an added mass and excess material consumption. Therefore, it is not always economical and effective from an optimization design view. In this paper, a topology optimization approach is presented to maximize the modal damping ratio of the plate with constrained layer damping treatment. The governing equation of motion of the plate is derived on the basis of energy approach. A finite element model to describe dynamic performances of the plate is developed and used along with an optimization algorithm in order to determine the optimal topologies of constrained layer damping layout on the plate. The damping of visco-elastic layer is modeled by the complex modulus formula. Considering the vibration and energy dissipation mode of the plate with constrained layer damping treatment, damping material density and volume factor are considered as design variable and constraint respectively. Meantime, the modal damping ratio of the plate is assigned as the objective function in the topology optimization approach. The sensitivity of modal damping ratio to design variable is further derived and Method of Moving Asymptote (MMA is adopted to search the optimized topologies of constrained layer damping layout on the plate. Numerical examples are used to demonstrate the effectiveness of the proposed topology optimization approach. The results show that vibration energy dissipation of the plates can be enhanced by the optimal constrained layer damping layout. This optimal technology can be further extended to vibration attenuation of sandwich cylindrical shells which constitute the major building block of many critical structures such as cabins of aircrafts, hulls of submarines and bodies of rockets and missiles as an

  16. Highly efficient fully transparent inverted OLEDs

    Science.gov (United States)

    Meyer, J.; Winkler, T.; Hamwi, S.; Schmale, S.; Kröger, M.; Görrn, P.; Johannes, H.-H.; Riedl, T.; Lang, E.; Becker, D.; Dobbertin, T.; Kowalsky, W.

    2007-09-01

    One of the unique selling propositions of OLEDs is their potential to realize highly transparent devices over the visible spectrum. This is because organic semiconductors provide a large Stokes-Shift and low intrinsic absorption losses. Hence, new areas of applications for displays and ambient lighting become accessible, for instance, the integration of OLEDs into the windshield or the ceiling of automobiles. The main challenge in the realization of fully transparent devices is the deposition of the top electrode. ITO is commonly used as transparent bottom anode in a conventional OLED. To obtain uniform light emission over the entire viewing angle and a low series resistance, a TCO such as ITO is desirable as top contact as well. However, sputter deposition of ITO on top of organic layers causes damage induced by high energetic particles and UV radiation. We have found an efficient process to protect the organic layers against the ITO rf magnetron deposition process of ITO for an inverted OLED (IOLED). The inverted structure allows the integration of OLEDs in more powerful n-channel transistors used in active matrix backplanes. Employing the green electrophosphorescent material Ir(ppy) 3 lead to IOLED with a current efficiency of 50 cd/A and power efficiency of 24 lm/W at 100 cd/m2. The average transmittance exceeds 80 % in the visible region. The on-set voltage for light emission is lower than 3 V. In addition, by vertical stacking we achieved a very high current efficiency of more than 70 cd/A for transparent IOLED.

  17. Towards a Fully Conservative Water Balance

    Science.gov (United States)

    Rodriguez, L. B.; Vionnet, C. A.; Younger, P. L.; Parkin, G.

    2001-12-01

    Hydrological modeling is nowadays an essential tool in many aspects of water resources assessment and management. For practical purposes, hydrological models may be defined as mathematical procedures, which transform meteorological input data such as precipitation and evapotranspiration into hydrological output values such as riverflows. Conceptual water balance models are one kind of hydrological models still quite popular among engineers and scientists for three main reasons: firstly the "book-keeping" procedure they are based upon makes them computationally inexpensive, secondly, they require far less data than any physically based model, and thirdly, once calibrated and validated, they can yield the proper order of magnitude of the water cycle component on the basin under investigation. A common criticism of water balance models is their lack of sound theoretical basis. In this work a fully conservative water balance model for basin applications which takes into account physical processes is presented. The two-storage level model contains four calibration parameters: a, b, l and Umax. The saturated storage component resembles the abcd model by Thomas, corrected by the presence of the aquifer storativity coefficient s and the river-aquifer interface conductance l. The resulting model is capable of estimating monthly basin-average of actual evapotranspiration, soil moisture, effective groundwater recharge, groundwater level fluctuations, baseflows and direct runoff using an integral form of the mass conservation law in the saturated/unsaturated layers. The model was applied to a 600 Km2 catchment in the United Kingdom. An eight-year record was used for calibration, while a similar record was reserved for validation of model results. Total streamflows as well as baseflows calculated by the model were compared with observed and estimated data. A quite good agreement was obtained. Finally, simulated groundwater levels were compared with observation data collected at

  18. Deterministic and stochastic evolution equations for fully dispersive and weakly nonlinear waves

    DEFF Research Database (Denmark)

    Eldeberky, Y.; Madsen, Per A.

    1999-01-01

    and stochastic formulations are solved numerically for the case of cross shore motion of unidirectional waves and the results are verified against laboratory data for wave propagation over submerged bars and over a plane slope. Outside the surf zone the two model predictions are generally in good agreement......This paper presents a new and more accurate set of deterministic evolution equations for the propagation of fully dispersive, weakly nonlinear, irregular, multidirectional waves. The equations are derived directly from the Laplace equation with leading order nonlinearity in the surface boundary...... is significantly underestimated for larger wave numbers. In the present work we correct this inconsistency. In addition to the improved deterministic formulation, we present improved stochastic evolution equations in terms of the energy spectrum and the bispectrum for multidirectional waves. The deterministic...

  19. 7 CFR 718.304 - Failure to fully comply.

    Science.gov (United States)

    2010-01-01

    ... authorized in accordance with § 718.305 if the participant made a good faith effort to comply fully with the... FSA approval official to have made a good faith effort to comply fully with the terms and conditions...

  20. Perfume formulation: words and chats.

    Science.gov (United States)

    Ellena, Céline

    2008-06-01

    What does it mean to create fragrances with materials from chemistry and/or from nature? How are they used to display their characteristic differences, their own personality? Is it easier to create with synthetic raw materials or with essential oils? This review explains why a perfume formulation corresponds in fact to a conversation, an interplay between synthetic and natural perfumery materials. A synthetic raw material carries a single information, and usually is very linear. Its smell is uniform, clear, and faithful. Natural raw materials, on the contrary, provide a strong, complex and generous image. While a synthetic material can be seen as a single word, a natural one such as rose oil could be compared to chatting: cold, warm, sticky, heavy, transparent, pepper, green, metallic, smooth, watery, fruity... full of information. Yet, if a very small amount of the natural material is used, nothing happens, the fragrance will not change. However, if a large amount is used, the rose oil will swallow up everything else. The fragrance will smell of nothing else except rose! To formulate a perfume is not to create a culinary recipe, with only dosing the ingredients in well-balanced amounts. To formulate rather means to flexibly knit materials together with a lively stitch, meeting or repelling each other, building a pleasant form, which is neither fixed, nor solid, nor rigid. A fragrance has an overall structure, which ranges from a clear sound, made up of stable, unique, and linear items, to a background chat, comfortable and reassuring. But that does, of course, not mean that there is only one way of creating a fragrance!

  1. Formulation of soy oil products

    Directory of Open Access Journals (Sweden)

    Woerfel, John B.

    1995-12-01

    Full Text Available The paper comments different formulations of soy oil products such as salad and cooking oils, margarine, shortenings, commercial shortenings, frying shortenings, and fluid shortenings. Hydrogenation and its influence on final products is also included.

    El trabajo presenta diferentes formulaciones a base de aceite de soja tales como aceites para ensalada y cocinado, margarina, grasas sólidas (shortenings, grasas sólidas comerciales, grasas sólidas para frituras y grasas fluidas. Hace también referencia al proceso de hidrogenación y a sus efectos en los productos finales.

  2. New approach to solve symmetric fully fuzzy linear systems

    Indian Academy of Sciences (India)

    concepts of fuzzy set theory and then define a fully fuzzy linear system of equations. .... To represent the above problem as fully fuzzy linear system, we represent x .... Fully fuzzy linear systems can be solved by Linear programming approach, ...

  3. Formulation and Characterization of Sustained Release Floating ...

    African Journals Online (AJOL)

    Purpose: To formulate sustained release gastroretentive microballoons of metformin hydrochloride with the objective of improving its bioavailability. Methods: Microballoons of metformin hydrochloride were formulated by solvent evaporation and diffusion method using varying mixtures of hydroxypropyl methylcellulose ...

  4. Bioequivalence assessment of two formulations of ibuprofen

    KAUST Repository

    Al-Talla, Zeyad; Akrawi, Sabah H; Tolley, Luke T; Sioud, Salim H; Zaater, Mohammed F; Emwas, Abdul-Hamid M

    2011-01-01

    Background: This study assessed the relative bioavailability of two formulations of ibuprofen. The first formulation was Doloraz , produced by Al-Razi Pharmaceutical Company, Amman, Jordan. The second forumulation was Brufen , manufactured by Boots

  5. Modern approach to relativity theory (radar formulation)

    International Nuclear Information System (INIS)

    Strel'tsov, V.N.

    1991-01-01

    The main peculiarities of the radar formulation of the relativity theory are presented. This formulation operates with the retarded (light) distances and relativistic or radar length introduced on their basis. 21 refs.; 1 tab

  6. Automatic Bayes Factors for Testing Equality- and Inequality-Constrained Hypotheses on Variances.

    Science.gov (United States)

    Böing-Messing, Florian; Mulder, Joris

    2018-05-03

    In comparing characteristics of independent populations, researchers frequently expect a certain structure of the population variances. These expectations can be formulated as hypotheses with equality and/or inequality constraints on the variances. In this article, we consider the Bayes factor for testing such (in)equality-constrained hypotheses on variances. Application of Bayes factors requires specification of a prior under every hypothesis to be tested. However, specifying subjective priors for variances based on prior information is a difficult task. We therefore consider so-called automatic or default Bayes factors. These methods avoid the need for the user to specify priors by using information from the sample data. We present three automatic Bayes factors for testing variances. The first is a Bayes factor with equal priors on all variances, where the priors are specified automatically using a small share of the information in the sample data. The second is the fractional Bayes factor, where a fraction of the likelihood is used for automatic prior specification. The third is an adjustment of the fractional Bayes factor such that the parsimony of inequality-constrained hypotheses is properly taken into account. The Bayes factors are evaluated by investigating different properties such as information consistency and large sample consistency. Based on this evaluation, it is concluded that the adjusted fractional Bayes factor is generally recommendable for testing equality- and inequality-constrained hypotheses on variances.

  7. Scheduling of resource-constrained projects

    CERN Document Server

    Klein, Robert

    2000-01-01

    Project management has become a widespread instrument enabling organizations to efficiently master the challenges of steadily shortening product life cycles, global markets and decreasing profit margins. With projects increasing in size and complexity, their planning and control represents one of the most crucial management tasks. This is especially true for scheduling, which is concerned with establishing execution dates for the sub-activities to be performed in order to complete the project. The ability to manage projects where resources must be allocated between concurrent projects or even sub-activities of a single project requires the use of commercial project management software packages. However, the results yielded by the solution procedures included are often rather unsatisfactory. Scheduling of Resource-Constrained Projects develops more efficient procedures, which can easily be integrated into software packages by incorporated programming languages, and thus should be of great interest for practiti...

  8. Constrained mathematics evaluation in probabilistic logic analysis

    Energy Technology Data Exchange (ETDEWEB)

    Arlin Cooper, J

    1998-06-01

    A challenging problem in mathematically processing uncertain operands is that constraints inherent in the problem definition can require computations that are difficult to implement. Examples of possible constraints are that the sum of the probabilities of partitioned possible outcomes must be one, and repeated appearances of the same variable must all have the identical value. The latter, called the 'repeated variable problem', will be addressed in this paper in order to show how interval-based probabilistic evaluation of Boolean logic expressions, such as those describing the outcomes of fault trees and event trees, can be facilitated in a way that can be readily implemented in software. We will illustrate techniques that can be used to transform complex constrained problems into trivial problems in most tree logic expressions, and into tractable problems in most other cases.

  9. Constraining dark sectors with monojets and dijets

    International Nuclear Information System (INIS)

    Chala, Mikael; Kahlhoefer, Felix; Nardini, Germano; Schmidt-Hoberg, Kai; McCullough, Matthew

    2015-03-01

    We consider dark sector particles (DSPs) that obtain sizeable interactions with Standard Model fermions from a new mediator. While these particles can avoid observation in direct detection experiments, they are strongly constrained by LHC measurements. We demonstrate that there is an important complementarity between searches for DSP production and searches for the mediator itself, in particular bounds on (broad) dijet resonances. This observation is crucial not only in the case where the DSP is all of the dark matter but whenever - precisely due to its sizeable interactions with the visible sector - the DSP annihilates away so efficiently that it only forms a dark matter subcomponent. To highlight the different roles of DSP direct detection and LHC monojet and dijet searches, as well as perturbativity constraints, we first analyse the exemplary case of an axial-vector mediator and then generalise our results. We find important implications for the interpretation of LHC dark matter searches in terms of simplified models.

  10. Quantum cosmology of classically constrained gravity

    International Nuclear Information System (INIS)

    Gabadadze, Gregory; Shang Yanwen

    2006-01-01

    In [G. Gabadadze, Y. Shang, hep-th/0506040] we discussed a classically constrained model of gravity. This theory contains known solutions of General Relativity (GR), and admits solutions that are absent in GR. Here we study cosmological implications of some of these new solutions. We show that a spatially-flat de Sitter universe can be created from 'nothing'. This universe has boundaries, and its total energy equals to zero. Although the probability to create such a universe is exponentially suppressed, it favors initial conditions suitable for inflation. Then we discuss a finite-energy solution with a nonzero cosmological constant and zero space-time curvature. There is no tunneling suppression to fluctuate into this state. We show that for a positive cosmological constant this state is unstable-it can rapidly transition to a de Sitter universe providing a new unsuppressed channel for inflation. For a negative cosmological constant the space-time flat solutions is stable.

  11. Multiple Clustering Views via Constrained Projections

    DEFF Research Database (Denmark)

    Dang, Xuan-Hong; Assent, Ira; Bailey, James

    2012-01-01

    Clustering, the grouping of data based on mutual similarity, is often used as one of principal tools to analyze and understand data. Unfortunately, most conventional techniques aim at finding only a single clustering over the data. For many practical applications, especially those being described...... in high dimensional data, it is common to see that the data can be grouped into different yet meaningful ways. This gives rise to the recently emerging research area of discovering alternative clusterings. In this preliminary work, we propose a novel framework to generate multiple clustering views....... The framework relies on a constrained data projection approach by which we ensure that a novel alternative clustering being found is not only qualitatively strong but also distinctively different from a reference clustering solution. We demonstrate the potential of the proposed framework using both synthetic...

  12. Shape space exploration of constrained meshes

    KAUST Repository

    Yang, Yongliang

    2011-12-12

    We present a general computational framework to locally characterize any shape space of meshes implicitly prescribed by a collection of non-linear constraints. We computationally access such manifolds, typically of high dimension and co-dimension, through first and second order approximants, namely tangent spaces and quadratically parameterized osculant surfaces. Exploration and navigation of desirable subspaces of the shape space with regard to application specific quality measures are enabled using approximants that are intrinsic to the underlying manifold and directly computable in the parameter space of the osculant surface. We demonstrate our framework on shape spaces of planar quad (PQ) meshes, where each mesh face is constrained to be (nearly) planar, and circular meshes, where each face has a circumcircle. We evaluate our framework for navigation and design exploration on a variety of inputs, while keeping context specific properties such as fairness, proximity to a reference surface, etc. © 2011 ACM.

  13. Shape space exploration of constrained meshes

    KAUST Repository

    Yang, Yongliang; Yang, Yijun; Pottmann, Helmut; Mitra, Niloy J.

    2011-01-01

    We present a general computational framework to locally characterize any shape space of meshes implicitly prescribed by a collection of non-linear constraints. We computationally access such manifolds, typically of high dimension and co-dimension, through first and second order approximants, namely tangent spaces and quadratically parameterized osculant surfaces. Exploration and navigation of desirable subspaces of the shape space with regard to application specific quality measures are enabled using approximants that are intrinsic to the underlying manifold and directly computable in the parameter space of the osculant surface. We demonstrate our framework on shape spaces of planar quad (PQ) meshes, where each mesh face is constrained to be (nearly) planar, and circular meshes, where each face has a circumcircle. We evaluate our framework for navigation and design exploration on a variety of inputs, while keeping context specific properties such as fairness, proximity to a reference surface, etc. © 2011 ACM.

  14. Constrained vertebrate evolution by pleiotropic genes.

    Science.gov (United States)

    Hu, Haiyang; Uesaka, Masahiro; Guo, Song; Shimai, Kotaro; Lu, Tsai-Ming; Li, Fang; Fujimoto, Satoko; Ishikawa, Masato; Liu, Shiping; Sasagawa, Yohei; Zhang, Guojie; Kuratani, Shigeru; Yu, Jr-Kai; Kusakabe, Takehiro G; Khaitovich, Philipp; Irie, Naoki

    2017-11-01

    Despite morphological diversification of chordates over 550 million years of evolution, their shared basic anatomical pattern (or 'bodyplan') remains conserved by unknown mechanisms. The developmental hourglass model attributes this to phylum-wide conserved, constrained organogenesis stages that pattern the bodyplan (the phylotype hypothesis); however, there has been no quantitative testing of this idea with a phylum-wide comparison of species. Here, based on data from early-to-late embryonic transcriptomes collected from eight chordates, we suggest that the phylotype hypothesis would be better applied to vertebrates than chordates. Furthermore, we found that vertebrates' conserved mid-embryonic developmental programmes are intensively recruited to other developmental processes, and the degree of the recruitment positively correlates with their evolutionary conservation and essentiality for normal development. Thus, we propose that the intensively recruited genetic system during vertebrates' organogenesis period imposed constraints on its diversification through pleiotropic constraints, which ultimately led to the common anatomical pattern observed in vertebrates.

  15. Constraining Lyman continuum escape using Machine Learning

    Science.gov (United States)

    Giri, Sambit K.; Zackrisson, Erik; Binggeli, Christian; Pelckmans, Kristiaan; Cubo, Rubén; Mellema, Garrelt

    2018-05-01

    The James Webb Space Telescope (JWST) will observe the rest-frame ultraviolet/optical spectra of galaxies from the epoch of reionization (EoR) in unprecedented detail. While escaping into the intergalactic medium, hydrogen-ionizing (Lyman continuum; LyC) photons from the galaxies will contribute to the bluer end of the UV slope and make nebular emission lines less prominent. We present a method to constrain leakage of the LyC photons using the spectra of high redshift (z >~ 6) galaxies. We simulate JWST/NIRSpec observations of galaxies at z =6-9 by matching the fluxes of galaxies observed in the Frontier Fields observations of galaxy cluster MACS-J0416. Our method predicts the escape fraction fesc with a mean absolute error Δfesc ~ 0.14. The method also predicts the redshifts of the galaxies with an error .

  16. Statistical mechanics of budget-constrained auctions

    International Nuclear Information System (INIS)

    Altarelli, F; Braunstein, A; Realpe-Gomez, J; Zecchina, R

    2009-01-01

    Finding the optimal assignment in budget-constrained auctions is a combinatorial optimization problem with many important applications, a notable example being in the sale of advertisement space by search engines (in this context the problem is often referred to as the off-line AdWords problem). On the basis of the cavity method of statistical mechanics, we introduce a message-passing algorithm that is capable of solving efficiently random instances of the problem extracted from a natural distribution, and we derive from its properties the phase diagram of the problem. As the control parameter (average value of the budgets) is varied, we find two phase transitions delimiting a region in which long-range correlations arise

  17. Constraining Dark Sectors with Monojets and Dijets

    CERN Document Server

    Chala, Mikael; McCullough, Matthew; Nardini, Germano; Schmidt-Hoberg, Kai

    2015-01-01

    We consider dark sector particles (DSPs) that obtain sizeable interactions with Standard Model fermions from a new mediator. While these particles can avoid observation in direct detection experiments, they are strongly constrained by LHC measurements. We demonstrate that there is an important complementarity between searches for DSP production and searches for the mediator itself, in particular bounds on (broad) dijet resonances. This observation is crucial not only in the case where the DSP is all of the dark matter but whenever - precisely due to its sizeable interactions with the visible sector - the DSP annihilates away so efficiently that it only forms a dark matter subcomponent. To highlight the different roles of DSP direct detection and LHC monojet and dijet searches, as well as perturbativity constraints, we first analyse the exemplary case of an axial-vector mediator and then generalise our results. We find important implications for the interpretation of LHC dark matter searches in terms of simpli...

  18. Statistical mechanics of budget-constrained auctions

    Science.gov (United States)

    Altarelli, F.; Braunstein, A.; Realpe-Gomez, J.; Zecchina, R.

    2009-07-01

    Finding the optimal assignment in budget-constrained auctions is a combinatorial optimization problem with many important applications, a notable example being in the sale of advertisement space by search engines (in this context the problem is often referred to as the off-line AdWords problem). On the basis of the cavity method of statistical mechanics, we introduce a message-passing algorithm that is capable of solving efficiently random instances of the problem extracted from a natural distribution, and we derive from its properties the phase diagram of the problem. As the control parameter (average value of the budgets) is varied, we find two phase transitions delimiting a region in which long-range correlations arise.

  19. Constrained least squares regularization in PET

    International Nuclear Information System (INIS)

    Choudhury, K.R.; O'Sullivan, F.O.

    1996-01-01

    Standard reconstruction methods used in tomography produce images with undesirable negative artifacts in background and in areas of high local contrast. While sophisticated statistical reconstruction methods can be devised to correct for these artifacts, their computational implementation is excessive for routine operational use. This work describes a technique for rapid computation of approximate constrained least squares regularization estimates. The unique feature of the approach is that it involves no iterative projection or backprojection steps. This contrasts with the familiar computationally intensive algorithms based on algebraic reconstruction (ART) or expectation-maximization (EM) methods. Experimentation with the new approach for deconvolution and mixture analysis shows that the root mean square error quality of estimators based on the proposed algorithm matches and usually dominates that of more elaborate maximum likelihood, at a fraction of the computational effort

  20. Constraining dark sectors with monojets and dijets

    Energy Technology Data Exchange (ETDEWEB)

    Chala, Mikael; Kahlhoefer, Felix; Nardini, Germano; Schmidt-Hoberg, Kai [Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany); McCullough, Matthew [European Organization for Nuclear Research (CERN), Geneva (Switzerland). Theory Div.

    2015-03-15

    We consider dark sector particles (DSPs) that obtain sizeable interactions with Standard Model fermions from a new mediator. While these particles can avoid observation in direct detection experiments, they are strongly constrained by LHC measurements. We demonstrate that there is an important complementarity between searches for DSP production and searches for the mediator itself, in particular bounds on (broad) dijet resonances. This observation is crucial not only in the case where the DSP is all of the dark matter but whenever - precisely due to its sizeable interactions with the visible sector - the DSP annihilates away so efficiently that it only forms a dark matter subcomponent. To highlight the different roles of DSP direct detection and LHC monojet and dijet searches, as well as perturbativity constraints, we first analyse the exemplary case of an axial-vector mediator and then generalise our results. We find important implications for the interpretation of LHC dark matter searches in terms of simplified models.

  1. Constraining the dark side with observations

    International Nuclear Information System (INIS)

    Diez-Tejedor, Alberto

    2007-01-01

    The main purpose of this talk is to use the observational evidences pointing out to the existence of a dark side in the universe in order to infer some of the properties of the unseen material. We will work within the Unified Dark Matter models, in which both, Dark Matter and Dark Energy appear as the result of one unknown component. By modeling effectively this component with a classical scalar field minimally coupled to gravity, we will use the observations to constrain the form of the dark action. Using the flat rotation curves of spiral galaxies we will see that we are restringed to the use of purely kinetic actions, previously studied in cosmology by Scherrer. Finally we arrive to a simple action which fits both cosmological and astrophysical observations

  2. Constraining the dark side with observations

    Energy Technology Data Exchange (ETDEWEB)

    Diez-Tejedor, Alberto [Dpto. de Fisica Teorica, Universidad del PaIs Vasco, Apdo. 644, 48080, Bilbao (Spain)

    2007-05-15

    The main purpose of this talk is to use the observational evidences pointing out to the existence of a dark side in the universe in order to infer some of the properties of the unseen material. We will work within the Unified Dark Matter models, in which both, Dark Matter and Dark Energy appear as the result of one unknown component. By modeling effectively this component with a classical scalar field minimally coupled to gravity, we will use the observations to constrain the form of the dark action. Using the flat rotation curves of spiral galaxies we will see that we are restringed to the use of purely kinetic actions, previously studied in cosmology by Scherrer. Finally we arrive to a simple action which fits both cosmological and astrophysical observations.

  3. Hard exclusive meson production to constrain GPDs

    Energy Technology Data Exchange (ETDEWEB)

    Wolbeek, Johannes ter; Fischer, Horst; Gorzellik, Matthias; Gross, Arne; Joerg, Philipp; Koenigsmann, Kay; Malm, Pasquale; Regali, Christopher; Schmidt, Katharina; Sirtl, Stefan; Szameitat, Tobias [Physikalisches Institut, Albert-Ludwigs-Universitaet Freiburg, Freiburg im Breisgau (Germany); Collaboration: COMPASS Collaboration

    2014-07-01

    The concept of Generalized Parton Distributions (GPDs) combines the two-dimensional spatial information, given by form factors, with the longitudinal momentum information from the PDFs. Thus, GPDs provide a three-dimensional 'tomography' of the nucleon. Furthermore, according to Ji's sum rule, the GPDs H and E enable access to the total angular momenta of quarks, antiquarks and gluons. While H can be approached using electroproduction cross section, hard exclusive meson production off a transversely polarized target can help to constrain the GPD E. At the COMPASS experiment at CERN, two periods of data taking were performed in 2007 and 2010, using a longitudinally polarized 160 GeV/c muon beam and a transversely polarized NH{sub 3} target. This talk introduces the data analysis of the process μ + p → μ' + p' + V, and recent results are presented.

  4. Formulation, Preparation, and Characterization of Polyurethane Foams

    Science.gov (United States)

    Pinto, Moises L.

    2010-01-01

    Preparation of laboratory-scale polyurethane foams is described with formulations that are easy to implement in experiments for undergraduate students. Particular attention is given to formulation aspects that are based on the main chemical reactions occurring in polyurethane production. This allows students to develop alternative formulations to…

  5. Performance Evaluation of Abrasive Grinding Wheel Formulated ...

    African Journals Online (AJOL)

    This paper presents a study on the formulation and manufacture of abrasive grinding wheel using locally formulated silicon carbide abrasive grains. Six local raw material substitutes were identified through pilot study and with the initial mix of the identified materials, a systematic search for an optimal formulation of silicon ...

  6. Optimization of chlorphenesin emulgel formulation.

    Science.gov (United States)

    Mohamed, Magdy I

    2004-10-11

    This study was conducted to develop an emulgel formulation of chlorphenesin (CHL) using 2 types of gelling agents: hydroxypropylmethyl cellulose (HPMC) and Carbopol 934. The influence of the type of the gelling agent and the concentration of both the oil phase and emulsifying agent on the drug release from the prepared emulgels was investigated using a 2(3) factorial design. The prepared emulgels were evaluated for their physical appearance, rheological behavior, drug release, antifungal activity, and stability. Commercially available CHL topical powder was used for comparison. All the prepared emulgels showed acceptable physical properties concerning color, homogeneity, consistency, spreadability, and pH value. They also exhibited higher drug release and antifungal activity than the CHL powder. It was found that the emulsifying agent concentration had the most pronounced effect on the drug release from the emulgels followed by the oil phase concentration and finally the type of the gelling agent. The drug release from all the emulgels was found to follow diffusion-controlled mechanism. Rheological studies revealed that the CHL emulgels exhibited a shear-thinning behavior with thixotropy. Stability studies showed that the physical appearance, rheological properties, drug release, and antifungal activity in all the prepared emulgels remained unchanged upon storage for 3 months. As a general conclusion, it was suggested that the CHL emulgel formulation prepared with HPMC with the oil phase concentration in its low level and emulsifying agent concentration in its high level was the formula of choice since it showed the highest drug release and antifungal activity.

  7. Variational formulation of relaxed and multi-region relaxed magnetohydrodynamics

    Science.gov (United States)

    Dewar, R. L.; Yoshida, Z.; Bhattacharjee, A.; Hudson, S. R.

    2015-12-01

    > Ideal magnetohydrodynamics (IMHD) is strongly constrained by an infinite number of microscopic constraints expressing mass, entropy and magnetic flux conservation in each infinitesimal fluid element, the latter preventing magnetic reconnection. By contrast, in the Taylor relaxation model for formation of macroscopically self-organized plasma equilibrium states, all these constraints are relaxed save for the global magnetic fluxes and helicity. A Lagrangian variational principle is presented that leads to a new, fully dynamical, relaxed magnetohydrodynamics (RxMHD), such that all static solutions are Taylor states but also allows state with flow. By postulating that some long-lived macroscopic current sheets can act as barriers to relaxation, separating the plasma into multiple relaxation regions, a further generalization, multi-region relaxed magnetohydrodynamics (MRxMHD) is developed.

  8. Constraining the neutrino magnetic dipole moment from white dwarf pulsations

    International Nuclear Information System (INIS)

    Córsico, A.H.; Althaus, L.G.; Bertolami, M.M. Miller; Kepler, S.O.; García-Berro, E.

    2014-01-01

    Pulsating white dwarf stars can be used as astrophysical laboratories to constrain the properties of weakly interacting particles. Comparing the cooling rates of these stars with the expected values from theoretical models allows us to search for additional sources of cooling due to the emission of axions, neutralinos, or neutrinos with magnetic dipole moment. In this work, we derive an upper bound to the neutrino magnetic dipole moment (μ ν ) using an estimate of the rate of period change of the pulsating DB white dwarf star PG 1351+489. We employ state-of-the-art evolutionary and pulsational codes which allow us to perform a detailed asteroseismological period fit based on fully DB white dwarf evolutionary sequences. Plasmon neutrino emission is the dominant cooling mechanism for this class of hot pulsating white dwarfs, and so it is the main contributor to the rate of change of period with time (Pidot) for the DBV class. Thus, the inclusion of an anomalous neutrino emission through a non-vanishing magnetic dipole moment in these sequences notably influences the evolutionary timescales, and also the expected pulsational properties of the DBV stars. By comparing the theoretical Pidot value with the rate of change of period with time of PG 1351+489, we assess the possible existence of additional cooling by neutrinos with magnetic dipole moment. Our models suggest the existence of some additional cooling in this pulsating DB white dwarf, consistent with a non-zero magnetic dipole moment with an upper limit of μ ν  ∼< 10 -11  μ B . This bound is somewhat less restrictive than, but still compatible with, other limits inferred from the white dwarf luminosity function or from the color-magnitude diagram of the Globular cluster M5. Further improvements of the measurement of the rate of period change of the dominant pulsation mode of PG 1351+489 will be necessary to confirm our bound

  9. A HARDCORE model for constraining an exoplanet's core size

    Science.gov (United States)

    Suissa, Gabrielle; Chen, Jingjing; Kipping, David

    2018-05-01

    The interior structure of an exoplanet is hidden from direct view yet likely plays a crucial role in influencing the habitability of the Earth analogues. Inferences of the interior structure are impeded by a fundamental degeneracy that exists between any model comprising more than two layers and observations constraining just two bulk parameters: mass and radius. In this work, we show that although the inverse problem is indeed degenerate, there exists two boundary conditions that enables one to infer the minimum and maximum core radius fraction, CRFmin and CRFmax. These hold true even for planets with light volatile envelopes, but require the planet to be fully differentiated and that layers denser than iron are forbidden. With both bounds in hand, a marginal CRF can also be inferred by sampling in-between. After validating on the Earth, we apply our method to Kepler-36b and measure CRFmin = (0.50 ± 0.07), CRFmax = (0.78 ± 0.02), and CRFmarg = (0.64 ± 0.11), broadly consistent with the Earth's true CRF value of 0.55. We apply our method to a suite of hypothetical measurements of synthetic planets to serve as a sensitivity analysis. We find that CRFmin and CRFmax have recovered uncertainties proportional to the relative error on the planetary density, but CRFmarg saturates to between 0.03 and 0.16 once (Δρ/ρ) drops below 1-2 per cent. This implies that mass and radius alone cannot provide any better constraints on internal composition once bulk density constraints hit around a per cent, providing a clear target for observers.

  10. Formulation development for PREPP concreted waste forms

    International Nuclear Information System (INIS)

    Neilson, R.M. Jr.; Welch, J.M.

    1984-05-01

    Analysis of variance and logistic regression techniques have been used to develop models describing the effects of formulation variables and their interactions on compressive strength, solidification, free-standing water, and workability of hydraulic cement grouts incorporating simulated Process Experimental Pilot Plant (PREPP) wastes. These models provide the basis for specifications of grout formulations to solidify these wastes. The experimental test matrix, formulation preparation, and test methods employed are described. The development of analytical models for formulation behavior and the conclusions drawn regarding appropriate formulation variable ranges are discussed. 13 references, 9 figures, 15 tables

  11. Application of pattern search method to power system security constrained economic dispatch with non-smooth cost function

    International Nuclear Information System (INIS)

    Al-Othman, A.K.; El-Naggar, K.M.

    2008-01-01

    Direct search methods are evolutionary algorithms used to solve optimization problems. (DS) methods do not require any information about the gradient of the objective function at hand while searching for an optimum solution. One of such methods is Pattern Search (PS) algorithm. This paper presents a new approach based on a constrained pattern search algorithm to solve a security constrained power system economic dispatch problem (SCED) with non-smooth cost function. Operation of power systems demands a high degree of security to keep the system satisfactorily operating when subjected to disturbances, while and at the same time it is required to pay attention to the economic aspects. Pattern recognition technique is used first to assess dynamic security. Linear classifiers that determine the stability of electric power system are presented and added to other system stability and operational constraints. The problem is formulated as a constrained optimization problem in a way that insures a secure-economic system operation. Pattern search method is then applied to solve the constrained optimization formulation. In particular, the method is tested using three different test systems. Simulation results of the proposed approach are compared with those reported in literature. The outcome is very encouraging and proves that pattern search (PS) is very applicable for solving security constrained power system economic dispatch problem (SCED). In addition, valve-point effect loading and total system losses are considered to further investigate the potential of the PS technique. Based on the results, it can be concluded that the PS has demonstrated ability in handling highly nonlinear discontinuous non-smooth cost function of the SCED. (author)

  12. Energy policy formulation for Pakistan

    International Nuclear Information System (INIS)

    Riaz, T.

    1981-01-01

    Pakistan is a low income, low energy consumption country. In view of the close interdependence between economic growth and energy consumption, she will need increasing energy supplies in order to maintain her economic growth. This paper develops an energy sector optimization model for the Pakistan economy, which consists of production models for five energy industries, ie oil, gas, coal, electricity (including electricity generated in nuclear power plants) and non-commercial fuels. The model is first used to forecast energy balances for the period 1975 - 2006. The model is then employed to formulate a long-term comprehensive energy policy for Pakistan. Finally the suggested policy is compared with the current official energy programme. (author)

  13. On Scalar Energy: Mathematical Formulation

    International Nuclear Information System (INIS)

    Hathout, A.M.

    2011-01-01

    A new kind of electromagnetic waves (EMW), which exists only in vacuum of the empty space, will be discussed and mathematically formulated in this paper. The mathematical existence of this energy was first proposed in a series of groundbreaking equations by Scottish Mathematician, James Clerk Maxwell, in the mid of 1800 and 39;s. This energy is called scalar energy. It is characterized by both particle and wave like. The waves of this energy are called longitudinal EMW to distinguish them from transverse EM, the kind we are familiar with in our daily life. Teslas name of this energy is scalar energy or zero point energy. It is aimed at this paper to explain more details and to verify the scalar EM concept in vacuum.

  14. Reflected stochastic differential equation models for constrained animal movement

    Science.gov (United States)

    Hanks, Ephraim M.; Johnson, Devin S.; Hooten, Mevin B.

    2017-01-01

    Movement for many animal species is constrained in space by barriers such as rivers, shorelines, or impassable cliffs. We develop an approach for modeling animal movement constrained in space by considering a class of constrained stochastic processes, reflected stochastic differential equations. Our approach generalizes existing methods for modeling unconstrained animal movement. We present methods for simulation and inference based on augmenting the constrained movement path with a latent unconstrained path and illustrate this augmentation with a simulation example and an analysis of telemetry data from a Steller sea lion (Eumatopias jubatus) in southeast Alaska.

  15. Stability of buffer-free freeze-dried formulations: A feasibility study of a monoclonal antibody at high protein concentrations.

    Science.gov (United States)

    Garidel, Patrick; Pevestorf, Benjamin; Bahrenburg, Sven

    2015-11-01

    We studied the stability of freeze-dried therapeutic protein formulations over a range of initial concentrations (from 40 to 160 mg/mL) and employed a variety of formulation strategies (including buffer-free freeze dried formulations, or BF-FDF). Highly concentrated, buffer-free liquid formulations of therapeutic monoclonal antibodies (mAbs) have been shown to be a viable alternative to conventionally buffered preparations. We considered whether it is feasible to use the buffer-free strategy in freeze-dried formulations, as an answer to some of the known drawbacks of conventional buffers. We therefore conducted an accelerated stability study (24 weeks at 40 °C) to assess the feasibility of stabilizing freeze-dried formulations without "classical" buffer components. Factors monitored included pH stability, protein integrity, and protein aggregation. Because the protein solutions are inherently self-buffering, and the system's buffer capacity scales with protein concentration, we included highly concentrated buffer-free freeze-dried formulations in the study. The tested formulations ranged from "fully formulated" (containing both conventional buffer and disaccharide stabilizers) to "buffer-free" (including formulations with only disaccharide lyoprotectant stabilizers) to "excipient-free" (with neither added buffers nor stabilizers). We evaluated the impacts of varying concentrations, buffering schemes, pHs, and lyoprotectant additives. At the end of 24 weeks, no change in pH was observed in any of the buffer-free formulations. Unbuffered formulations were found to have shorter reconstitution times and lower opalescence than buffered formulations. Protein stability was assessed by visual inspection, sub-visible particle analysis, protein monomer content, charge variants analysis, and hydrophobic interaction chromatography. All of these measures found the stability of buffer-free formulations that included a disaccharide stabilizer comparable to buffer

  16. Effects of Atelocollagen Formulation Containing Oligonucleotide on Endothelial Permeability

    Directory of Open Access Journals (Sweden)

    Koji Hanai

    2012-01-01

    Full Text Available Atelocollagen is a major animal protein that is used as a highly biocompatible biomaterial. To date, atelocollagen has been used as an effective drug delivery technology to sustain the release of antitumor proteins and to enhance the antitumor activity of oligonucleotides in in vivo models. However, the biological effects of this technology are not fully understood. In the present study, we investigated the effects of atelocollagen on endothelial paracellular barrier function. An atelocollagen formulation containing oligonucleotides specifically increased the permeability of two types of endothelial cells, and the change was dependent on the molecular size, structure of the oligonucleotides used and the concentrations of the oligonucleotide and atelocollagen in the formulation. An immunohistochemical examination revealed that the formulation had effects on the cellular skeleton and intercellular structure although it did not affect the expression of adherens junction or tight junction proteins. These changes were induced through p38 MAP kinase signaling. It is important to elucidate the biological functions of atelocollagen in order to be able to exploit its drug delivery properties.

  17. Sequential unconstrained minimization algorithms for constrained optimization

    International Nuclear Information System (INIS)

    Byrne, Charles

    2008-01-01

    The problem of minimizing a function f(x):R J → R, subject to constraints on the vector variable x, occurs frequently in inverse problems. Even without constraints, finding a minimizer of f(x) may require iterative methods. We consider here a general class of iterative algorithms that find a solution to the constrained minimization problem as the limit of a sequence of vectors, each solving an unconstrained minimization problem. Our sequential unconstrained minimization algorithm (SUMMA) is an iterative procedure for constrained minimization. At the kth step we minimize the function G k (x)=f(x)+g k (x), to obtain x k . The auxiliary functions g k (x):D subset of R J → R + are nonnegative on the set D, each x k is assumed to lie within D, and the objective is to minimize the continuous function f:R J → R over x in the set C = D-bar, the closure of D. We assume that such minimizers exist, and denote one such by x-circumflex. We assume that the functions g k (x) satisfy the inequalities 0≤g k (x)≤G k-1 (x)-G k-1 (x k-1 ), for k = 2, 3, .... Using this assumption, we show that the sequence {(x k )} is decreasing and converges to f(x-circumflex). If the restriction of f(x) to D has bounded level sets, which happens if x-circumflex is unique and f(x) is closed, proper and convex, then the sequence {x k } is bounded, and f(x*)=f(x-circumflex), for any cluster point x*. Therefore, if x-circumflex is unique, x* = x-circumflex and {x k } → x-circumflex. When x-circumflex is not unique, convergence can still be obtained, in particular cases. The SUMMA includes, as particular cases, the well-known barrier- and penalty-function methods, the simultaneous multiplicative algebraic reconstruction technique (SMART), the proximal minimization algorithm of Censor and Zenios, the entropic proximal methods of Teboulle, as well as certain cases of gradient descent and the Newton–Raphson method. The proof techniques used for SUMMA can be extended to obtain related results

  18. Message formulation, organization, and navigation schemes for icon-based communication aids.

    Science.gov (United States)

    Patel, Rupal

    2011-01-01

    Individuals with severe speech and motor impairments rely on assistive communication devices to convey their needs and desires in social, educational, and vocational situations. Users with limited motor control or literacy often choose to use icon-based devices that afford increased speed of message formulation at the cost of fully generative language formulation on letter-based devices. A major challenge with large vocabulary icon-based systems is rate of communication. Message formulation, vocabulary organization, and navigation schemes can be used to mitigate the trade-off between vocabulary size and communication rate. This paper summarizes our research efforts to leverage semantic frame theory, situational context, and rapid serial visual presentation to improve message formulation speed and completeness in our iconCHAT and RSVP iconCHAT systems. Usability data and persisting challenges are discussed.

  19. Sparseness- and continuity-constrained seismic imaging

    Science.gov (United States)

    Herrmann, Felix J.

    2005-04-01

    Non-linear solution strategies to the least-squares seismic inverse-scattering problem with sparseness and continuity constraints are proposed. Our approach is designed to (i) deal with substantial amounts of additive noise (SNR formulating the solution of the seismic inverse problem in terms of an optimization problem. During the optimization, sparseness on the basis and continuity along the reflectors are imposed by jointly minimizing the l1- and anisotropic diffusion/total-variation norms on the coefficients and reflectivity, respectively. [Joint work with Peyman P. Moghaddam was carried out as part of the SINBAD project, with financial support secured through ITF (the Industry Technology Facilitator) from the following organizations: BG Group, BP, ExxonMobil, and SHELL. Additional funding came from the NSERC Discovery Grants 22R81254.

  20. Constrained Sypersymmetric Flipped SU (5) GUT Phenomenology

    Energy Technology Data Exchange (ETDEWEB)

    Ellis, John; /CERN /King' s Coll. London; Mustafayev, Azar; /Minnesota U., Theor. Phys. Inst.; Olive, Keith A.; /Minnesota U., Theor. Phys. Inst. /Minnesota U. /Stanford U., Phys. Dept. /SLAC

    2011-08-12

    We explore the phenomenology of the minimal supersymmetric flipped SU(5) GUT model (CFSU(5)), whose soft supersymmetry-breaking (SSB) mass parameters are constrained to be universal at some input scale, Min, above the GUT scale, M{sub GUT}. We analyze the parameter space of CFSU(5) assuming that the lightest supersymmetric particle (LSP) provides the cosmological cold dark matter, paying careful attention to the matching of parameters at the GUT scale. We first display some specific examples of the evolutions of the SSB parameters that exhibit some generic features. Specifically, we note that the relationship between the masses of the lightest neutralino {chi} and the lighter stau {tilde {tau}}{sub 1} is sensitive to M{sub in}, as is the relationship between m{sub {chi}} and the masses of the heavier Higgs bosons A,H. For these reasons, prominent features in generic (m{sub 1/2}, m{sub 0}) planes such as coannihilation strips and rapid-annihilation funnels are also sensitive to Min, as we illustrate for several cases with tan {beta} = 10 and 55. However, these features do not necessarily disappear at large Min, unlike the case in the minimal conventional SU(5) GUT. Our results are relatively insensitive to neutrino masses.

  1. Constrained supersymmetric flipped SU(5) GUT phenomenology

    Energy Technology Data Exchange (ETDEWEB)

    Ellis, John [CERN, TH Division, PH Department, Geneva 23 (Switzerland); King' s College London, Theoretical Physics and Cosmology Group, Department of Physics, London (United Kingdom); Mustafayev, Azar [University of Minnesota, William I. Fine Theoretical Physics Institute, Minneapolis, MN (United States); Olive, Keith A. [University of Minnesota, William I. Fine Theoretical Physics Institute, Minneapolis, MN (United States); Stanford University, Department of Physics and SLAC, Palo Alto, CA (United States)

    2011-07-15

    We explore the phenomenology of the minimal supersymmetric flipped SU(5) GUT model (CFSU(5)), whose soft supersymmetry-breaking (SSB) mass parameters are constrained to be universal at some input scale, M{sub in}, above the GUT scale, M{sub GUT}. We analyze the parameter space of CFSU(5) assuming that the lightest supersymmetric particle (LSP) provides the cosmological cold dark matter, paying careful attention to the matching of parameters at the GUT scale. We first display some specific examples of the evolutions of the SSB parameters that exhibit some generic features. Specifically, we note that the relationship between the masses of the lightest neutralino {chi} and the lighter stau {tau}{sub 1} is sensitive to M{sub in}, as is the relationship between m{sub {chi}} and the masses of the heavier Higgs bosons A,H. For these reasons, prominent features in generic (m{sub 1/2},m{sub 0}) planes such as coannihilation strips and rapid-annihilation funnels are also sensitive to M{sub in}, as we illustrate for several cases with tan {beta}=10 and 55. However, these features do not necessarily disappear at large M{sub in}, unlike the case in the minimal conventional SU(5) GUT. Our results are relatively insensitive to neutrino masses. (orig.)

  2. Joint Chance-Constrained Dynamic Programming

    Science.gov (United States)

    Ono, Masahiro; Kuwata, Yoshiaki; Balaram, J. Bob

    2012-01-01

    This paper presents a novel dynamic programming algorithm with a joint chance constraint, which explicitly bounds the risk of failure in order to maintain the state within a specified feasible region. A joint chance constraint cannot be handled by existing constrained dynamic programming approaches since their application is limited to constraints in the same form as the cost function, that is, an expectation over a sum of one-stage costs. We overcome this challenge by reformulating the joint chance constraint into a constraint on an expectation over a sum of indicator functions, which can be incorporated into the cost function by dualizing the optimization problem. As a result, the primal variables can be optimized by a standard dynamic programming, while the dual variable is optimized by a root-finding algorithm that converges exponentially. Error bounds on the primal and dual objective values are rigorously derived. We demonstrate the algorithm on a path planning problem, as well as an optimal control problem for Mars entry, descent and landing. The simulations are conducted using a real terrain data of Mars, with four million discrete states at each time step.

  3. Constraining the roughness degree of slip heterogeneity

    KAUST Repository

    Causse, Mathieu

    2010-05-07

    This article investigates different approaches for assessing the degree of roughness of the slip distribution of future earthquakes. First, we analyze a database of slip images extracted from a suite of 152 finite-source rupture models from 80 events (Mw = 4.1–8.9). This results in an empirical model defining the distribution of the slip spectrum corner wave numbers (kc) as a function of moment magnitude. To reduce the “epistemic” uncertainty, we select a single slip model per event and screen out poorly resolved models. The number of remaining models (30) is thus rather small. In addition, the robustness of the empirical model rests on a reliable estimation of kc by kinematic inversion methods. We address this issue by performing tests on synthetic data with a frequency domain inversion method. These tests reveal that due to smoothing constraints used to stabilize the inversion process, kc tends to be underestimated. We then develop an alternative approach: (1) we establish a proportionality relationship between kc and the peak ground acceleration (PGA), using a k−2 kinematic source model, and (2) we analyze the PGA distribution, which is believed to be better constrained than slip images. These two methods reveal that kc follows a lognormal distribution, with similar standard deviations for both methods.

  4. Technologies for a greenhouse-constrained society

    International Nuclear Information System (INIS)

    Kuliasha, M.A.; Zucker, A.; Ballew, K.J.

    1992-01-01

    This conference explored how three technologies might help society adjust to life in a greenhouse-constrained environment. Technology experts and policy makers from around the world met June 11--13, 1991, in Oak Ridge, Tennessee, to address questions about how energy efficiency, biomass, and nuclear technologies can mitigate the greenhouse effect and to explore energy production and use in countries in various stages of development. The conference was organized by Oak Ridge National Laboratory and sponsored by the US Department of Energy. Energy efficiency biomass, and nuclear energy are potential substitutes for fossil fuels that might help slow or even reverse the global warming changes that may result from mankind's thirst for energy. Many other conferences have questioned whether the greenhouse effect is real and what reductions in greenhouse gas emissions might be necessary to avoid serious ecological consequences; this conference studied how these reductions might actually be achieved. For these conference proceedings, individuals papers are processed separately for the Energy Data Base

  5. Constrained Supersymmetric Flipped SU(5) GUT Phenomenology

    CERN Document Server

    Ellis, John; Olive, Keith A

    2011-01-01

    We explore the phenomenology of the minimal supersymmetric flipped SU(5) GUT model (CFSU(5)), whose soft supersymmetry-breaking (SSB) mass parameters are constrained to be universal at some input scale, $M_{in}$, above the GUT scale, $M_{GUT}$. We analyze the parameter space of CFSU(5) assuming that the lightest supersymmetric particle (LSP) provides the cosmological cold dark matter, paying careful attention to the matching of parameters at the GUT scale. We first display some specific examples of the evolutions of the SSB parameters that exhibit some generic features. Specifically, we note that the relationship between the masses of the lightest neutralino and the lighter stau is sensitive to $M_{in}$, as is the relationship between the neutralino mass and the masses of the heavier Higgs bosons. For these reasons, prominent features in generic $(m_{1/2}, m_0)$ planes such as coannihilation strips and rapid-annihilation funnels are also sensitive to $M_{in}$, as we illustrate for several cases with tan(beta)...

  6. Constrained supersymmetric flipped SU(5) GUT phenomenology

    International Nuclear Information System (INIS)

    Ellis, John; Mustafayev, Azar; Olive, Keith A.

    2011-01-01

    We explore the phenomenology of the minimal supersymmetric flipped SU(5) GUT model (CFSU(5)), whose soft supersymmetry-breaking (SSB) mass parameters are constrained to be universal at some input scale, M in , above the GUT scale, M GUT . We analyze the parameter space of CFSU(5) assuming that the lightest supersymmetric particle (LSP) provides the cosmological cold dark matter, paying careful attention to the matching of parameters at the GUT scale. We first display some specific examples of the evolutions of the SSB parameters that exhibit some generic features. Specifically, we note that the relationship between the masses of the lightest neutralino χ and the lighter stau τ 1 is sensitive to M in , as is the relationship between m χ and the masses of the heavier Higgs bosons A,H. For these reasons, prominent features in generic (m 1/2 ,m 0 ) planes such as coannihilation strips and rapid-annihilation funnels are also sensitive to M in , as we illustrate for several cases with tan β=10 and 55. However, these features do not necessarily disappear at large M in , unlike the case in the minimal conventional SU(5) GUT. Our results are relatively insensitive to neutrino masses. (orig.)

  7. Scheduling Aircraft Landings under Constrained Position Shifting

    Science.gov (United States)

    Balakrishnan, Hamsa; Chandran, Bala

    2006-01-01

    Optimal scheduling of airport runway operations can play an important role in improving the safety and efficiency of the National Airspace System (NAS). Methods that compute the optimal landing sequence and landing times of aircraft must accommodate practical issues that affect the implementation of the schedule. One such practical consideration, known as Constrained Position Shifting (CPS), is the restriction that each aircraft must land within a pre-specified number of positions of its place in the First-Come-First-Served (FCFS) sequence. We consider the problem of scheduling landings of aircraft in a CPS environment in order to maximize runway throughput (minimize the completion time of the landing sequence), subject to operational constraints such as FAA-specified minimum inter-arrival spacing restrictions, precedence relationships among aircraft that arise either from airline preferences or air traffic control procedures that prevent overtaking, and time windows (representing possible control actions) during which each aircraft landing can occur. We present a Dynamic Programming-based approach that scales linearly in the number of aircraft, and describe our computational experience with a prototype implementation on realistic data for Denver International Airport.

  8. Should we still believe in constrained supersymmetry?

    International Nuclear Information System (INIS)

    Balazs, Csaba; Buckley, Andy; Carter, Daniel; Farmer, Benjamin; White, Martin

    2013-01-01

    We calculate partial Bayes factors to quantify how the feasibility of the constrained minimal supersymmetric standard model (CMSSM) has changed in the light of a series of observations. This is done in the Bayesian spirit where probability reflects a degree of belief in a proposition and Bayes' theorem tells us how to update it after acquiring new information. Our experimental baseline is the approximate knowledge that was available before LEP, and our comparison model is the Standard Model with a simple dark matter candidate. To quantify the amount by which experiments have altered our relative belief in the CMSSM since the baseline data we compute the partial Bayes factors that arise from learning in sequence the LEP Higgs constraints, the XENON100 dark matter constraints, the 2011 LHC supersymmetry search results, and the early 2012 LHC Higgs search results. We find that LEP and the LHC strongly shatter our trust in the CMSSM (with M 0 and M 1/2 below 2 TeV), reducing its posterior odds by approximately two orders of magnitude. This reduction is largely due to substantial Occam factors induced by the LEP and LHC Higgs searches. (orig.)

  9. Electricity in a Climate-Constrained World

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2012-07-01

    After experiencing a historic drop in 2009, electricity generation reached a record high in 2010, confirming the close linkage between economic growth and electricity usage. Unfortunately, CO2 emissions from electricity have also resumed their growth: Electricity remains the single-largest source of CO2 emissions from energy, with 11.7 billion tonnes of CO2 released in 2010. The imperative to 'decarbonise' electricity and improve end-use efficiency remains essential to the global fight against climate change. The IEA’s Electricity in a Climate-Constrained World provides an authoritative resource on progress to date in this area, including statistics related to CO2 and the electricity sector across ten regions of the world (supply, end-use and capacity additions). It also presents topical analyses on the challenge of rapidly curbing CO2 emissions from electricity. Looking at policy instruments, it focuses on emissions trading in China, using energy efficiency to manage electricity supply crises and combining policy instruments for effective CO2 reductions. On regulatory issues, it asks whether deregulation can deliver decarbonisation and assesses the role of state-owned enterprises in emerging economies. And from technology perspectives, it explores the rise of new end-uses, the role of electricity storage, biomass use in Brazil, and the potential of carbon capture and storage for ‘negative emissions’ electricity supply.

  10. Chance-constrained/stochastic linear programming model for acid rain abatement. I. Complete colinearity and noncolinearity

    Energy Technology Data Exchange (ETDEWEB)

    Ellis, J H; McBean, E A; Farquhar, G J

    1985-01-01

    A Linear Programming model is presented for development of acid rain abatement strategies in eastern North America. For a system comprised of 235 large controllable point sources and 83 uncontrolled area sources, it determines the least-cost method of reducing SO/sub 2/ emissions to satisfy maximum wet sulfur deposition limits at 20 sensitive receptor locations. In this paper, the purely deterministic model is extended to a probabilistic form by incorporating the effects of meteorologic variability on the long-range pollutant transport processes. These processes are represented by source-receptor-specific transfer coefficients. Experiments for quantifying the spatial variability of transfer coefficients showed their distributions to be approximately lognormal with logarithmic standard deviations consistently about unity. Three methods of incorporating second-moment random variable uncertainty into the deterministic LP framework are described: Two-Stage Programming Under Uncertainty, Chance-Constrained Programming and Stochastic Linear Programming. A composite CCP-SLP model is developed which embodies the two-dimensional characteristics of transfer coefficient uncertainty. Two probabilistic formulations are described involving complete colinearity and complete noncolinearity for the transfer coefficient covariance-correlation structure. The completely colinear and noncolinear formulations are considered extreme bounds in a meteorologic sense and yield abatement strategies of largely didactic value. Such strategies can be characterized as having excessive costs and undesirable deposition results in the completely colinear case and absence of a clearly defined system risk level (other than expected-value) in the noncolinear formulation.

  11. A GENERALIZED DIFFUSION TENSOR FOR FULLY ANISOTROPIC DIFFUSION OF ENERGETIC PARTICLES IN THE HELIOSPHERIC MAGNETIC FIELD

    International Nuclear Information System (INIS)

    Effenberger, F.; Fichtner, H.; Scherer, K.; Barra, S.; Kleimann, J.; Strauss, R. D.

    2012-01-01

    The spatial diffusion of cosmic rays in turbulent magnetic fields can, in the most general case, be fully anisotropic, i.e., one has to distinguish three diffusion axes in a local, field-aligned frame. We reexamine the transformation for the diffusion tensor from this local to a global frame, in which the Parker transport equation for energetic particles is usually formulated and solved. Particularly, we generalize the transformation formulae to allow for an explicit choice of two principal local perpendicular diffusion axes. This generalization includes the 'traditional' diffusion tensor in the special case of isotropic perpendicular diffusion. For the local frame, we describe the motivation for the choice of the Frenet-Serret trihedron, which is related to the intrinsic magnetic field geometry. We directly compare the old and the new tensor elements for two heliospheric magnetic field configurations, namely the hybrid Fisk and Parker fields. Subsequently, we examine the significance of the different formulations for the diffusion tensor in a standard three-dimensional model for the modulation of galactic protons. For this, we utilize a numerical code to evaluate a system of stochastic differential equations equivalent to the Parker transport equation and present the resulting modulated spectra. The computed differential fluxes based on the new tensor formulation deviate from those obtained with the 'traditional' one (only valid for isotropic perpendicular diffusion) by up to 60% for energies below a few hundred MeV depending on heliocentric distance.

  12. Constraining the proton structure at ATLAS

    CERN Document Server

    Tricoli, Alessandro; Viehhauser, Georg

    Particle physics is at a pivotal moment: the origin of mass and new physics scenarios beyond the Standard Model or particle physics could be unveiled in the coming year. In 2007 the most powerful particl e accelerator, the Large Hadron Coolider (LHC), will start colliding proton beams reaching the ihghest energy and luminosity ever in collider particle physics. The ATLAS detector is one of two general pu rpose detectors placed along the collider ring to fully exploit the LHC potential. The theoretical uncertainties on most of the LHC physics progream are dominated by the proton structure uncertaintiy. This thesis demonstrates that $W^{\\pm}$ boson productionis an ideal process to constr ain the proton strcuture uncertainty. The rapidity distributions of electrons and positrons originating respectively from the $W^-$ and $W^+$ decays have been analysed. The results show that the current uncertainty on the gluon content of the proton can be reduced by a very significant amount if the total systematic uncertaint...

  13. A discretized algorithm for the solution of a constrained, continuous ...

    African Journals Online (AJOL)

    A discretized algorithm for the solution of a constrained, continuous quadratic control problem. ... The results obtained show that the Discretized constrained algorithm (DCA) is much more accurate and more efficient than some of these techniques, particularly the FSA. Journal of the Nigerian Association of Mathematical ...

  14. I/O-Efficient Construction of Constrained Delaunay Triangulations

    DEFF Research Database (Denmark)

    Agarwal, Pankaj Kumar; Arge, Lars; Yi, Ke

    2005-01-01

    In this paper, we designed and implemented an I/O-efficient algorithm for constructing constrained Delaunay triangulations. If the number of constraining segments is smaller than the memory size, our algorithm runs in expected O( N B logM/B NB ) I/Os for triangulating N points in the plane, where...

  15. Evaluation of a Fully Automated Analyzer for Rapid Measurement of Water Vapor Sorption Isotherms for Applications in Soil Science

    DEFF Research Database (Denmark)

    Arthur, Emmanuel; Tuller, Markus; Moldrup, Per

    2014-01-01

    The characterization and description of important soil processes such as water vapor transport, volatilization of pesticides, and hysteresis require accurate means for measuring the soil water characteristic (SWC) at low water potentials. Until recently, measurement of the SWC at low water...... potentials was constrained by hydraulic decoupling and long equilibration times when pressure plates or single-point, chilled-mirror instruments were used. A new, fully automated Vapor Sorption Analyzer (VSA) helps to overcome these challenges and allows faster measurement of highly detailed water vapor...

  16. Thermoreversible gel formulation containing sodium lauryl sulfate as a potential contraceptive device.

    Science.gov (United States)

    Haineault, Caroline; Gourde, Pierrette; Perron, Sylvie; Désormeaux, André; Piret, Jocelyne; Omar, Rabeea F; Tremblay, Roland R; Bergeron, Michel G

    2003-08-01

    The contraceptive properties of a gel formulation containing sodium lauryl sulfate were investigated in both in vitro and in vivo models. Results showed that sodium lauryl sulfate inhibited, in a concentration-dependent manner, the activity of sheep testicular hyaluronidase. Sodium lauryl sulfate also completely inhibited human sperm motility as evaluated by the 30-sec Sander-Cramer test. The acid-buffering capacity of gel formulations containing sodium lauryl sulfate increased with the molarity of the citrate buffers used for their preparations. Furthermore, experiments in which semen was mixed with undiluted gel formulations in different proportions confirmed their physiologically relevant buffering capacity. Intravaginal application of the gel formulation containing sodium lauryl sulfate to rabbits before their artificial insemination with freshly ejaculated semen completely prevented egg fertilization. The gel formulation containing sodium lauryl sulfate was fully compatible with nonlubricated latex condoms. Taken together, these results suggest that the gel formulation containing sodium lauryl sulfate could represent a potential candidate for use as a topical vaginal spermicidal formulation to provide fertility control in women.

  17. Slag-based saltstone formulations

    International Nuclear Information System (INIS)

    Langton, C.A.

    1987-01-01

    Approximately 400 x 10 6 liters of low-level alkaline salt solution will be treated at the Savannah River Plant (SRP) Defense Waste Processing Facility (DWPF) prior to disposal in concrete vaults at SRP. Treatment involves removal of CS + and Sr +2 followed by solidification and stabilization of potential contaminants in saltstone, a hydrated ceramic waste form. Chromium, technetium, and nitrate releases from saltstone can be significantly reduced by substituting hydraulic blast furnace slag for portland cement in the formulation designs. Slag-based mixes are also compatible with Class F fly ash used in saltstone as a functional extender to control heat of hydration and reduce permeability. A monolithic waste form is produced by the hydration of the slag and fly ash. Soluble ion release (NO 3 - ) is controlled by the saltstone microstructure. Chromium and technetium are less leachable from slag mixes compared to cement-based waste forms because these species are chemically reduced to a lower valence state by ferrous iron in the slag and precipitated as relatively insoluble phases, such as CR(OH) 3 and TcO 2 . 5 refs., 4 figs., 4 tabs

  18. Slag-based saltstone formulations

    International Nuclear Information System (INIS)

    Langton, C.A.

    1987-08-01

    Approximately 400 x 10 6 L of low-level alkaline salt solution will be treated at the Savannah River Plant (SRP) Defense Waste Processing Facility (DWPF) prior to disposal in concrete vaults at SRP. Treatment involves removal of Cs + and Sr +2 , followed by solidification and stabilization of potential contaminants in saltstone, a hydrated ceramic wasteform. Chromium, technetium, and nitrate releases from saltstone can be significantly reduced by substituting hydraulic blast furnace slag for portland cement in the formulation designs. Slag-based mixes are also compatible with the Class F flyash used in saltstone as a functional extender to control heat of hydration and reduce permeability. (Class F flyash is also locally available at SRP.) A monolithic wasteform is produced by the hydration of the slag and flyash. Soluble ion release (NO 3- ) is controlled by the saltstone microstructure. Chromium and technetium are less leachable from slag mixes because these species are chemically reduced to a lower valence state by ferrous iron in the slag and are precipitated as relatively insoluble phases, such as Cr(OH) 3 and TcO 2 . 3 refs., 3 figs., 2 tabs

  19. Policy formulation of public acceptance

    International Nuclear Information System (INIS)

    Kasai, Akihiro

    1978-01-01

    Since 1970, the new policy formulation for public acceptance of the new consideration on the location of electric power generation has been set and applied. The planning and the enforcement being conducted by local public organizations for the local economic build-up with plant location and also the adjustement of the requirements for fishery are two main specific characters in this new policy. The background of this new public acceptance policy, the history and the actual problems about the compensation for the location of power generation plants are reviewed. One new proposal, being recommended by the Policy and Science Laboratory to MITI in 1977 is explained. This is based on the method of promoting the location of power generation plants by public participation placing the redevelopment of regional societies as its basis. The problems concerning the industrial structures in farm villages, fishing villages and the areas of commerce and industry should be systematized, and explained from the viewpoint of outside impact, the characteristics of local areas and the location problems in this new proposal. Finally, the location process and its effectiveness should be put in order. (Nakai, Y.)

  20. Hamiltonian formulation of reduced magnetohydrodynamics

    International Nuclear Information System (INIS)

    Morrison, P.J.; Hazeltine, R.D.

    1983-07-01

    Reduced magnetohydrodynamics (RMHD) has become a principal tool for understanding nonlinear processes, including disruptions, in tokamak plasmas. Although analytical studies of RMHD turbulence have been useful, the model's impressive ability to simulate tokamak fluid behavior has been revealed primarily by numerical solution. The present work describes a new analytical approach, not restricted to turbulent regimes, based on Hamiltonian field theory. It is shown that the nonlinear (ideal) RMHD system, in both its high-beta and low-beta versions, can be expressed in Hanmiltonian form. Thus a Poisson bracket, [ , ], is constructed such that each RMHD field quantitity, xi/sub i/, evolves according to xi/sub i/ = [xi/sub i/,H], where H is the total field energy. The new formulation makes RMHD accessible to the methodology of Hamiltonian mechanics; it has lead, in particular, to the recognition of new RMHD invariants and even exact, nonlinear RMHD solutions. A canonical version of the Poisson bracket, which requires the introduction of additional fields, leads to a nonlinear variational principle for time-dependent RMHD

  1. Formulation of disperse systems science and technology

    CERN Document Server

    Tadros, Tharwat F

    2014-01-01

    This book presents comprehensively the science and technology behind the formulation of disperse systems like emulsions, suspensions, foams and others. Starting with a general introduction, the book covers a broad range of topics like the role of different classes of surfactants, stability of disperse systems, formulation of different dispersions, evaluation of formulations and many more. Many examples are included, too. Written by the experienced author and editor Tharwart Tadros, this book is indispensable for every scientist working in the field.

  2. Formulated arthropod cadavers for pest suppression

    OpenAIRE

    2001-01-01

    Pesticidal and/or antimicrobial biological agent-infected arthropod cadavers are formulated by applying a coating agent once on the surface of the cadaver which either (a) prevents the cadavers from sticking together and/or rupturing or (b) acts as an adhesive for a powder or granule applied to the cadaver to prevent sticking and rupturing. The formulated cadavers maintain or improve infectivity, reproducibility, and survivability. The formulated cadavers can be partially desiccated to improv...

  3. Multiple excitation of supports - Part 1. Formulation

    International Nuclear Information System (INIS)

    Galeao, A.C.N.R.; Barbosa, H.J.C.

    1980-12-01

    The formulation and the solution of a simple specific problem of support movement are presented. The formulation is extended to the general case of infinitesimal elasticity where the approximated solutions are obtained by the variational formulation with spatial discretization by Finite Element Method. Finally, the present usual numerical techniques for the treatment of the resulting ordinary differential equations system are discused: Direct integration, Modal overlap, Spectral response. (E.G.) [pt

  4. Fully implicit Particle-in-cell algorithms for multiscale plasma simulation

    Energy Technology Data Exchange (ETDEWEB)

    Chacon, Luis [Los Alamos National Laboratory

    2015-07-16

    The outline of the paper is as follows: Particle-in-cell (PIC) methods for fully ionized collisionless plasmas, explicit vs. implicit PIC, 1D ES implicit PIC (charge and energy conservation, moment-based acceleration), and generalization to Multi-D EM PIC: Vlasov-Darwin model (review and motivation for Darwin model, conservation properties (energy, charge, and canonical momenta), and numerical benchmarks). The author demonstrates a fully implicit, fully nonlinear, multidimensional PIC formulation that features exact local charge conservation (via a novel particle mover strategy), exact global energy conservation (no particle self-heating or self-cooling), adaptive particle orbit integrator to control errors in momentum conservation, and canonical momenta (EM-PIC only, reduced dimensionality). The approach is free of numerical instabilities: ωpeΔt >> 1, and Δx >> λD. It requires many fewer dofs (vs. explicit PIC) for comparable accuracy in challenging problems. Significant CPU gains (vs explicit PIC) have been demonstrated. The method has much potential for efficiency gains vs. explicit in long-time-scale applications. Moment-based acceleration is effective in minimizing NFE, leading to an optimal algorithm.

  5. Regional Responses to Constrained Water Availability

    Science.gov (United States)

    Cui, Y.; Calvin, K. V.; Hejazi, M. I.; Clarke, L.; Kim, S. H.; Patel, P.

    2017-12-01

    There have been many concerns about water as a constraint to agricultural production, electricity generation, and many other human activities in the coming decades. Nevertheless, how different countries/economies would respond to such constraints has not been explored. Here, we examine the responding mechanism of binding water availability constraints at the water basin level and across a wide range of socioeconomic, climate and energy technology scenarios. Specifically, we look at the change in water withdrawals between energy, land-use and other sectors within an integrated framework, by using the Global Change Assessment Model (GCAM) that also endogenizes water use and allocation decisions based on costs. We find that, when water is taken into account as part of the production decision-making, countries/basins in general fall into three different categories, depending on the change of water withdrawals and water re-allocation between sectors. First, water is not a constraining factor for most of the basins. Second, advancements in water-saving technologies of the electricity generation cooling systems are sufficient of reducing water withdrawals to meet binding water availability constraints, such as in China and the EU-15. Third, water-saving in the electricity sector alone is not sufficient and thus cannot make up the lowered water availability from the binding case; for example, many basins in Pakistan, Middle East and India have to largely reduce irrigated water withdrawals by either switching to rain-fed agriculture or reducing production. The dominant responding strategy for individual countries/basins is quite robust across the range of alternate scenarios that we test. The relative size of water withdrawals between energy and agriculture sectors is one of the most important factors that affect the dominant mechanism.

  6. Constraining Cosmic Evolution of Type Ia Supernovae

    Energy Technology Data Exchange (ETDEWEB)

    Foley, Ryan J.; Filippenko, Alexei V.; Aguilera, C.; Becker, A.C.; Blondin, S.; Challis, P.; Clocchiatti, A.; Covarrubias, R.; Davis, T.M.; Garnavich, P.M.; Jha, S.; Kirshner, R.P.; Krisciunas, K.; Leibundgut, B.; Li, W.; Matheson, T.; Miceli, A.; Miknaitis, G.; Pignata, G.; Rest, A.; Riess, A.G.; /UC, Berkeley, Astron. Dept. /Cerro-Tololo InterAmerican Obs. /Washington U., Seattle, Astron. Dept. /Harvard-Smithsonian Ctr. Astrophys. /Chile U., Catolica /Bohr Inst. /Notre Dame U. /KIPAC, Menlo Park /Texas A-M /European Southern Observ. /NOAO, Tucson /Fermilab /Chile U., Santiago /Harvard U., Phys. Dept. /Baltimore, Space Telescope Sci. /Johns Hopkins U. /Res. Sch. Astron. Astrophys., Weston Creek /Stockholm U. /Hawaii U. /Illinois U., Urbana, Astron. Dept.

    2008-02-13

    We present the first large-scale effort of creating composite spectra of high-redshift type Ia supernovae (SNe Ia) and comparing them to low-redshift counterparts. Through the ESSENCE project, we have obtained 107 spectra of 88 high-redshift SNe Ia with excellent light-curve information. In addition, we have obtained 397 spectra of low-redshift SNe through a multiple-decade effort at Lick and Keck Observatories, and we have used 45 ultraviolet spectra obtained by HST/IUE. The low-redshift spectra act as a control sample when comparing to the ESSENCE spectra. In all instances, the ESSENCE and Lick composite spectra appear very similar. The addition of galaxy light to the Lick composite spectra allows a nearly perfect match of the overall spectral-energy distribution with the ESSENCE composite spectra, indicating that the high-redshift SNe are more contaminated with host-galaxy light than their low-redshift counterparts. This is caused by observing objects at all redshifts with similar slit widths, which corresponds to different projected distances. After correcting for the galaxy-light contamination, subtle differences in the spectra remain. We have estimated the systematic errors when using current spectral templates for K-corrections to be {approx}0.02 mag. The variance in the composite spectra give an estimate of the intrinsic variance in low-redshift maximum-light SN spectra of {approx}3% in the optical and growing toward the ultraviolet. The difference between the maximum-light low and high-redshift spectra constrain SN evolution between our samples to be < 10% in the rest-frame optical.

  7. Laterally constrained inversion for CSAMT data interpretation

    Science.gov (United States)

    Wang, Ruo; Yin, Changchun; Wang, Miaoyue; Di, Qingyun

    2015-10-01

    Laterally constrained inversion (LCI) has been successfully applied to the inversion of dc resistivity, TEM and airborne EM data. However, it hasn't been yet applied to the interpretation of controlled-source audio-frequency magnetotelluric (CSAMT) data. In this paper, we apply the LCI method for CSAMT data inversion by preconditioning the Jacobian matrix. We apply a weighting matrix to Jacobian to balance the sensitivity of model parameters, so that the resolution with respect to different model parameters becomes more uniform. Numerical experiments confirm that this can improve the convergence of the inversion. We first invert a synthetic dataset with and without noise to investigate the effect of LCI applications to CSAMT data, for the noise free data, the results show that the LCI method can recover the true model better compared to the traditional single-station inversion; and for the noisy data, the true model is recovered even with a noise level of 8%, indicating that LCI inversions are to some extent noise insensitive. Then, we re-invert two CSAMT datasets collected respectively in a watershed and a coal mine area in Northern China and compare our results with those from previous inversions. The comparison with the previous inversion in a coal mine shows that LCI method delivers smoother layer interfaces that well correlate to seismic data, while comparison with a global searching algorithm of simulated annealing (SA) in a watershed shows that though both methods deliver very similar good results, however, LCI algorithm presented in this paper runs much faster. The inversion results for the coal mine CSAMT survey show that a conductive water-bearing zone that was not revealed by the previous inversions has been identified by the LCI. This further demonstrates that the method presented in this paper works for CSAMT data inversion.

  8. Superspace formulation of new nonlinear sigma models

    International Nuclear Information System (INIS)

    Gates, S.J. Jr.

    1983-07-01

    The superspace formulation of two classes of supersymmetric nonlinear σ-models are presented. Two alternative N=1 superspace formulations are given for the d=2 supersymmetric nonlinear σ-models with Killing vector potentials: (a) formulation uses an active central charge and, (b) formulation uses a spurion superfield without inducing a classical breakdown of supersymmetry. The N=2 vector multiplet is used to construct a new class of d=4 nonlinear σ-models which when reduced to d=2 possess N=4 supersymmetry. Implications of these two classes of nonlinear σ-models for N>=4 superfield supergravity are discussed. (author)

  9. Renormalization group in the theory of fully developed turbulence. Problem of the infrared relevant corrections to the Navier-Stokes equation

    International Nuclear Information System (INIS)

    Antonov, N.V.; Borisenok, S.V.; Girina, V.I.

    1996-01-01

    Within the framework of the renormalization group approach to the theory of fully developed turbulence we consider the problem of possible IR relevant corrections to the Navier-Stokes equation. We formulate an exact criterion of the actual IR relevance of the corrections. In accordance with this criterion we verify the IR relevance for certain classes of composite operators. 17 refs., 2 tabs

  10. Design of a statically balanced fully compliant grasper

    NARCIS (Netherlands)

    Lamers, A.J.; Gallego Sanchez, J.A.; Herder, Justus Laurens

    2015-01-01

    Monolithic and thus fully compliant surgical graspers are promising when they provide equal or better force feedback than conventional graspers. In this work for the first time a fully compliant grasper is designed to exhibit zero stiffness and zero operation force. The design problem is addressed

  11. Glass Ceramic Formulation Data Package

    International Nuclear Information System (INIS)

    Crum, Jarrod V.; Rodriguez, Carmen P.; McCloy, John S.; Vienna, John D.; Chung, Chul-Woo

    2012-01-01

    A glass ceramic waste form is being developed for treatment of secondary waste streams generated by aqueous reprocessing of commercial used nuclear fuel (Crum et al. 2012b). The waste stream contains a mixture of transition metals, alkali, alkaline earths, and lanthanides, several of which exceed the solubility limits of a single phase borosilicate glass (Crum et al. 2009; Caurant et al. 2007). A multi-phase glass ceramic waste form allows incorporation of insoluble components of the waste by designed crystallization into durable heat tolerant phases. The glass ceramic formulation and processing targets the formation of the following three stable crystalline phases: (1) powellite (XMoO4) where X can be (Ca, Sr, Ba, and/or Ln), (2) oxyapatite Yx,Z(10-x)Si6O26 where Y is alkaline earth, Z is Ln, and (3) lanthanide borosilicate (Ln5BSi2O13). These three phases incorporate the waste components that are above the solubility limit of a single-phase borosilicate glass. The glass ceramic is designed to be a single phase melt, just like a borosilicate glass, and then crystallize upon slow cooling to form the targeted phases. The slow cooling schedule is based on the centerline cooling profile of a 2 foot diameter canister such as the Hanford High-Level Waste canister. Up to this point, crucible testing has been used for glass ceramic development, with cold crucible induction melter (CCIM) targeted as the ultimate processing technology for the waste form. Idaho National Laboratory (INL) will conduct a scaled CCIM test in FY2012 with a glass ceramic to demonstrate the processing behavior. This Data Package documents the laboratory studies of the glass ceramic composition to support the CCIM test. Pacific Northwest National Laboratory (PNNL) measured melt viscosity, electrical conductivity, and crystallization behavior upon cooling to identify a processing window (temperature range) for melter operation and cooling profiles necessary to crystallize the targeted phases in the

  12. Studying b --> s gamma at BABAR Using a Fully Inclusive Method

    Energy Technology Data Exchange (ETDEWEB)

    Schmitz, R

    2004-02-23

    The b {yields} s{gamma} decay represents a possible electromagnetic ''loop'' penguin decay of the B meson. This FCNC process is of high theoretical interest because various scenarios of new physics are expected to have contributions at the same (one loop) level as the Standard Model. The large sample of B{bar B} meson decays collected by the BaBar experiment makes a precision measurement of this rare decay possible. In conjunction with Standard Model predictions at the 10% level, it brings new physics effects into the realm of detection--or seriously constrains models that could predict them. A fully inclusive technique is presented to study the b {yields} s{gamma} transition as a function of photon energy, using 88.5 {+-} 1.0 x 10{sup 6} B{bar B} meson decays collected by the BaBar experiment in the years 2000 to 2002. The expected statistical and systematic uncertainties have been fully determined which enables first comparisons with theoretical predictions and other experimental results. It also lays the basis for the determination of the inclusive branching fraction {Beta}(B {yields} X{sub s}{gamma}) and the measurement of the photon energy spectrum.

  13. A Continuous Formulation for Logical Decisions in Differential Algebraic Systems using Mathematical Programs with Complementarity Constraints

    Directory of Open Access Journals (Sweden)

    Kody M. Powell

    2016-03-01

    Full Text Available This work presents a methodology to represent logical decisions in differential algebraic equation simulation and constrained optimization problems using a set of continuous algebraic equations. The formulations may be used when state variables trigger a change in process dynamics, and introduces a pseudo-binary decision variable, which is continuous, but should only have valid solutions at values of either zero or one within a finite time horizon. This formulation enables dynamic optimization problems with logical disjunctions to be solved by simultaneous solution methods without using methods such as mixed integer programming. Several case studies are given to illustrate the value of this methodology including nonlinear model predictive control of a chemical reactor using a surge tank with overflow to buffer disturbances in feed flow rate. Although this work contains novel methodologies for solving dynamic algebraic equation (DAE constrained problems where the system may experience an abrupt change in dynamics that may otherwise require a conditional statement, there remain substantial limitations to this methodology, including a limited domain where problems may converge and the possibility for ill-conditioning. Although the problems presented use only continuous algebraic equations, the formulation has inherent non-smoothness. Hence, these problems must be solved with care and only in select circumstances, such as in simulation or situations when the solution is expected to be near the solver’s initial point.

  14. Present-day kinematics of the Danakil block (southern Red Sea-Afar) constrained by GPS

    Science.gov (United States)

    Ladron de Guevara, R.; Jonsson, S.; Ruch, J.; Doubre, C.; Reilinger, R. E.; Ogubazghi, G.; Floyd, M.; Vasyura-Bathke, H.

    2017-12-01

    The rifting of the Arabian plate from the Nubian and Somalian plates is primarily accommodated by seismic and magmatic activity along two rift arms of the Afar triple junction (the Red Sea and Gulf of Aden rifts). The spatial distribution of active deformation in the Afar region have been constrained with geodetic observations. However, the plate boundary configuration in which this deformation occurs is still not fully understood. South of 17°N, the Red Sea rift is composed of two parallel and overlapping rift branches separated by the Danakil block. The distribution of the extension across these two overlapping rifts, their potential connection through a transform fault zone and the counterclockwise rotation of the Danakil block have not yet been fully resolved. Here we analyze new GPS observations from the Danakil block, the Gulf of Zula area (Eritrea) and Afar (Ethiopia) together with previous geodetic survey data to better constrain the plate kinematics and active deformation of the region. The new data has been collected in 2016 and add up to 5 years to the existing geodetic observations (going back to 2000). Our improved GPS velocity field shows differences with previously modeled GPS velocities, suggesting that the rate and rotation of the Danakil block need to be updated. The new velocity field also shows that the plate-boundary strain is accommodated by broad deformation zones rather than across sharp boundaries between tectonic blocks. To better determine the spatial distribution of the strain, we first implement a rigid block model to constrain the overall regional plate kinematics and to isolate the plate-boundary deformation at the western boundary of the Danakil block. We then study whether the recent southern Red Sea rifting events have caused detectable changes in observed GPS velocities and if the observations can be used to constrain the scale of this offshore rift activity. Finally, we investigate different geometries of transform faults that

  15. KINETIC CONSEQUENCES OF CONSTRAINING RUNNING BEHAVIOR

    Directory of Open Access Journals (Sweden)

    John A. Mercer

    2005-06-01

    Full Text Available It is known that impact forces increase with running velocity as well as when stride length increases. Since stride length naturally changes with changes in submaximal running velocity, it was not clear which factor, running velocity or stride length, played a critical role in determining impact characteristics. The aim of the study was to investigate whether or not stride length influences the relationship between running velocity and impact characteristics. Eight volunteers (mass=72.4 ± 8.9 kg; height = 1.7 ± 0.1 m; age = 25 ± 3.4 years completed two running conditions: preferred stride length (PSL and stride length constrained at 2.5 m (SL2.5. During each condition, participants ran at a variety of speeds with the intent that the range of speeds would be similar between conditions. During PSL, participants were given no instructions regarding stride length. During SL2.5, participants were required to strike targets placed on the floor that resulted in a stride length of 2.5 m. Ground reaction forces were recorded (1080 Hz as well as leg and head accelerations (uni-axial accelerometers. Impact force and impact attenuation (calculated as the ratio of head and leg impact accelerations were recorded for each running trial. Scatter plots were generated plotting each parameter against running velocity. Lines of best fit were calculated with the slopes recorded for analysis. The slopes were compared between conditions using paired t-tests. Data from two subjects were dropped from analysis since the velocity ranges were not similar between conditions resulting in the analysis of six subjects. The slope of impact force vs. velocity relationship was different between conditions (PSL: 0.178 ± 0.16 BW/m·s-1; SL2.5: -0.003 ± 0.14 BW/m·s-1; p < 0.05. The slope of the impact attenuation vs. velocity relationship was different between conditions (PSL: 5.12 ± 2.88 %/m·s-1; SL2.5: 1.39 ± 1.51 %/m·s-1; p < 0.05. Stride length was an important factor

  16. A New Resistance Formulation for Carbon Nanotubes

    Directory of Open Access Journals (Sweden)

    Ji-Huan He

    2008-01-01

    Full Text Available A new resistance formulation for carbon nanotubes is suggested using fractal approach. The new formulation is also valid for other nonmetal conductors including nerve fibers, conductive polymers, and molecular wires. Our theoretical prediction agrees well with experimental observation.

  17. Advanced Query Formulation in Deductive Databases.

    Science.gov (United States)

    Niemi, Timo; Jarvelin, Kalervo

    1992-01-01

    Discusses deductive databases and database management systems (DBMS) and introduces a framework for advanced query formulation for end users. Recursive processing is described, a sample extensional database is presented, query types are explained, and criteria for advanced query formulation from the end user's viewpoint are examined. (31…

  18. Aerosol formulation and clinical efficacy of bronchodilators

    NARCIS (Netherlands)

    Zanen, Pieter

    1998-01-01

    This thesis subject is the improvement of the formulation of inhaled aerosols. It is well known that the formulation of inhaled drugs is not optimal: the major part of the mass delivered does not reach the lower airways. This phenomenon is due to the particle size of the inhaled particles, which

  19. Hamiltonian formulation of anomaly free chiral bosons

    International Nuclear Information System (INIS)

    Abdalla, E.; Abdalla, M.C.B.; Devecchi, F.P.; Zadra, A.

    1988-01-01

    Starting out of an anomaly free Lagrangian formulation for chiral scalars, which a Wess-Zumino Term (to cancel the anomaly), we formulate the corresponding hamiltonian problem. Ther we use the (quantum) Siegel invariance to choose a particular, which turns out coincide with the obtained by Floreanini and Jackiw. (author) [pt

  20. Constraining global methane emissions and uptake by ecosystems

    International Nuclear Information System (INIS)

    Spahni, R.; Wania, R.; Neef, L.; Van Weele, M.; Van Velthoven, P.; Pison, I.; Bousquet, P.

    2011-01-01

    Natural methane (CH 4 ) emissions from wet ecosystems are an important part of today's global CH 4 budget. Climate affects the exchange of CH 4 between ecosystems and the atmosphere by influencing CH 4 production, oxidation, and transport in the soil. The net CH 4 exchange depends on ecosystem hydrology, soil and vegetation characteristics. Here, the LPJ-WHyMe global dynamical vegetation model is used to simulate global net CH 4 emissions for different ecosystems: northern peat-lands (45 degrees-90 degrees N), naturally inundated wetlands (60 degrees S-45 degrees N), rice agriculture and wet mineral soils. Mineral soils are a potential CH 4 sink, but can also be a source with the direction of the net exchange depending on soil moisture content. The geographical and seasonal distributions are evaluated against multi-dimensional atmospheric inversions for 2003-2005, using two independent four-dimensional variational assimilation systems. The atmospheric inversions are constrained by the atmospheric CH 4 observations of the SCIAMACHY satellite instrument and global surface networks. Compared to LPJ-WHyMe the inversions result in a significant reduction in the emissions from northern peat-lands and suggest that LPJ-WHyMe maximum annual emissions peak about one month late. The inversions do not put strong constraints on the division of sources between inundated wetlands and wet mineral soils in the tropics. Based on the inversion results we diagnose model parameters in LPJ-WHyMe and simulate the surface exchange of CH 4 over the period 1990-2008. Over the whole period we infer an increase of global ecosystem CH 4 emissions of +1.11 TgCH 4 yr -1 , not considering potential additional changes in wetland extent. The increase in simulated CH 4 emissions is attributed to enhanced soil respiration resulting from the observed rise in land temperature and in atmospheric carbon dioxide that were used as input. The long term decline of the atmospheric CH 4 growth rate from 1990

  1. Off-Line Robust Constrained MPC for Linear Time-Varying Systems with Persistent Disturbances

    Directory of Open Access Journals (Sweden)

    P. Bumroongsri

    2014-01-01

    Full Text Available An off-line robust constrained model predictive control (MPC algorithm for linear time-varying (LTV systems is developed. A novel feature is the fact that both model uncertainty and bounded additive disturbance are explicitly taken into account in the off-line formulation of MPC. In order to reduce the on-line computational burdens, a sequence of explicit control laws corresponding to a sequence of positively invariant sets is computed off-line. At each sampling time, the smallest positively invariant set containing the measured state is determined and the corresponding control law is implemented in the process. The proposed MPC algorithm can guarantee robust stability while ensuring the satisfaction of input and output constraints. The effectiveness of the proposed MPC algorithm is illustrated by two examples.

  2. A simple two stage optimization algorithm for constrained power economic dispatch

    International Nuclear Information System (INIS)

    Huang, G.; Song, K.

    1994-01-01

    A simple two stage optimization algorithm is proposed and investigated for fast computation of constrained power economic dispatch control problems. The method is a simple demonstration of the hierarchical aggregation-disaggregation (HAD) concept. The algorithm first solves an aggregated problem to obtain an initial solution. This aggregated problem turns out to be classical economic dispatch formulation, and it can be solved in 1% of overall computation time. In the second stage, linear programming method finds optimal solution which satisfies power balance constraints, generation and transmission inequality constraints and security constraints. Implementation of the algorithm for IEEE systems and EPRI Scenario systems shows that the two stage method obtains average speedup ratio 10.64 as compared to classical LP-based method

  3. Canonical symmetry of a constrained Hamiltonian system and canonical Ward identity

    International Nuclear Information System (INIS)

    Li, Zi-ping

    1995-01-01

    An algorithm for the construction of the generators of the gauge transformation of a constrained Hamiltonian system is given. The relationships among the coefficients connecting the first constraints in the generator are made clear. Starting from the phase space generating function of the Green function, the Ward identity in canonical formalism is deduced. We point out that the quantum equations of motion in canonical form for a system with singular Lagrangian differ from the classical ones whether Dirac's conjecture holds true or not. Applications of the present formulation to the Abelian and non-Abelian gauge theories are given. The expressions for PCAC and generalized PCAC of the AVV vertex are derived exactly from another point of view. A new form of the Ward identity for gauge-ghost proper vertices is obtained which differs from the usual Ward-Takahashi identity arising from the BRS invariance

  4. Constrained Quadratic Programming and Neurodynamics-Based Solver for Energy Optimization of Biped Walking Robots

    Directory of Open Access Journals (Sweden)

    Liyang Wang

    2017-01-01

    Full Text Available The application of biped robots is always trapped by their high energy consumption. This paper makes a contribution by optimizing the joint torques to decrease the energy consumption without changing the biped gaits. In this work, a constrained quadratic programming (QP problem for energy optimization is formulated. A neurodynamics-based solver is presented to solve the QP problem. Differing from the existing literatures, the proposed neurodynamics-based energy optimization (NEO strategy minimizes the energy consumption and guarantees the following three important constraints simultaneously: (i the force-moment equilibrium equation of biped robots, (ii frictions applied by each leg on the ground to hold the biped robot without slippage and tipping over, and (iii physical limits of the motors. Simulations demonstrate that the proposed strategy is effective for energy-efficient biped walking.

  5. L1 norm constrained migration of blended data with the FISTA algorithm

    International Nuclear Information System (INIS)

    Lu, Xinting; Han, Liguo; Yu, Jianglong; Chen, Xue

    2015-01-01

    Blended acquisition significantly improves the seismic acquisition efficiency. However, the direct imaging of blended data is not satisfactory due to the crosstalk contamination. Assuming that the distribution of subsurface reflectivity is sparse, in this paper, we formulate the seismic imaging problem of blended data as a Basis Pursuit denoise (BPDN) problem. Based on compressed sensing, we propose a L1 norm constrained migration method applying to the direct imaging of blended data. The Fast Iterative Shrinkage-Thresholding Algorithm, which is stable and computationally efficient, is implemented in our method. Numerical tests on the theoretical models show that the crosstalk introduced by blended sources is effectively attenuated and the migration quality has been improved enormously. (paper)

  6. Undefined cellulase formulations hinder scientific reproducibility.

    Science.gov (United States)

    Himmel, Michael E; Abbas, Charles A; Baker, John O; Bayer, Edward A; Bomble, Yannick J; Brunecky, Roman; Chen, Xiaowen; Felby, Claus; Jeoh, Tina; Kumar, Rajeev; McCleary, Barry V; Pletschke, Brett I; Tucker, Melvin P; Wyman, Charles E; Decker, Stephen R

    2017-01-01

    In the shadow of a burgeoning biomass-to-fuels industry, biological conversion of lignocellulose to fermentable sugars in a cost-effective manner is key to the success of second-generation and advanced biofuel production. For the effective comparison of one cellulase preparation to another, cellulase assays are typically carried out with one or more engineered cellulase formulations or natural exoproteomes of known performance serving as positive controls. When these formulations have unknown composition, as is the case with several widely used commercial products, it becomes impossible to compare or reproduce work done today to work done in the future, where, for example, such preparations may not be available. Therefore, being a critical tenet of science publishing, experimental reproducibility is endangered by the continued use of these undisclosed products. We propose the introduction of standard procedures and materials to produce specific and reproducible cellulase formulations. These formulations are to serve as yardsticks to measure improvements and performance of new cellulase formulations.

  7. Onomatopoeia characters extraction from comic images using constrained Delaunay triangulation

    Science.gov (United States)

    Liu, Xiangping; Shoji, Kenji; Mori, Hiroshi; Toyama, Fubito

    2014-02-01

    A method for extracting onomatopoeia characters from comic images was developed based on stroke width feature of characters, since they nearly have a constant stroke width in a number of cases. An image was segmented with a constrained Delaunay triangulation. Connected component grouping was performed based on the triangles generated by the constrained Delaunay triangulation. Stroke width calculation of the connected components was conducted based on the altitude of the triangles generated with the constrained Delaunay triangulation. The experimental results proved the effectiveness of the proposed method.

  8. Formulating a low-alkalinity cement for radioactive waste repositories

    International Nuclear Information System (INIS)

    Coumes, C. Cau Dit; Courtois, S.; Leclercq, S.; Bourbon, X.

    2004-01-01

    A multi-annual research program has been launched in January 2003 by CEA, EDF and ANDRA in order to formulate and characterize low-alkalinity and low-heat cements which would be compatible with an underground waste repository environment. Four types of bindings have been investigated: binary blends of Portland cement and silica fume or metakaolin, as well as ternary blends of Portland cement, fly ash and silica fume or metakaolin. Promising results have been obtained with a mixture comprising 37.5% Portland cement, 32.5% silica fume, and 30% fly ash: pH of water in equilibrium with fully hydrated cement is below 11. Moreover, silica fume compensates for the low reactivity of fly ash, while fly ash allows to reduce water demand, heat release, and dimensional variations of cement pastes and mortars. (authors)

  9. Formulating a low-alkalinity cement for radioactive waste repositories

    Energy Technology Data Exchange (ETDEWEB)

    Coumes, C. Cau Dit; Courtois, S.; Leclercq, S.; Bourbon, X

    2004-07-01

    A multi-annual research program has been launched in January 2003 by CEA, EDF and ANDRA in order to formulate and characterize low-alkalinity and low-heat cements which would be compatible with an underground waste repository environment. Four types of bindings have been investigated: binary blends of Portland cement and silica fume or metakaolin, as well as ternary blends of Portland cement, fly ash and silica fume or metakaolin. Promising results have been obtained with a mixture comprising 37.5% Portland cement, 32.5% silica fume, and 30% fly ash: pH of water in equilibrium with fully hydrated cement is below 11. Moreover, silica fume compensates for the low reactivity of fly ash, while fly ash allows to reduce water demand, heat release, and dimensional variations of cement pastes and mortars. (authors)

  10. Velocity potential formulations of highly accurate Boussinesq-type models

    DEFF Research Database (Denmark)

    Bingham, Harry B.; Madsen, Per A.; Fuhrman, David R.

    2009-01-01

    , B., 2006. A Boussinesq-type method for fully nonlinear waves interacting with a rapidly varying bathymetry. Coast. Eng. 53, 487-504); Jamois et al. (Jamois, E., Fuhrman, D.R., Bingham, H.B., Molin, B., 2006. Wave-structure interactions and nonlinear wave processes on the weather side of reflective...... with the kinematic bottom boundary condition. The true behaviour of the velocity potential formulation with respect to linear shoaling is given for the first time, correcting errors made by Jamois et al. (Jamois, E., Fuhrman, D.R., Bingham, H.B., Molin, B., 2006. Wave-structure interactions and nonlinear wave...... processes on the weather side of reflective structures. Coast. Eng. 53, 929-945). An exact infinite series solution for the potential is obtained via a Taylor expansion about an arbitrary vertical position z=(z) over cap. For practical implementation however, the solution is expanded based on a slow...

  11. Dynamically constrained ensemble perturbations – application to tides on the West Florida Shelf

    Directory of Open Access Journals (Sweden)

    F. Lenartz

    2009-07-01

    Full Text Available A method is presented to create an ensemble of perturbations that satisfies linear dynamical constraints. A cost function is formulated defining the probability of each perturbation. It is shown that the perturbations created with this approach take the land-sea mask into account in a similar way as variational analysis techniques. The impact of the land-sea mask is illustrated with an idealized configuration of a barrier island. Perturbations with a spatially variable correlation length can be also created by this approach. The method is applied to a realistic configuration of the West Florida Shelf to create perturbations of the M2 tidal parameters for elevation and depth-averaged currents. The perturbations are weakly constrained to satisfy the linear shallow-water equations. Despite that the constraint is derived from an idealized assumption, it is shown that this approach is applicable to a non-linear and baroclinic model. The amplitude of spurious transient motions created by constrained perturbations of initial and boundary conditions is significantly lower compared to perturbing the variables independently or to using only the momentum equation to compute the velocity perturbations from the elevation.

  12. Fuzzy Constrained Predictive Optimal Control of High Speed Train with Actuator Dynamics

    Directory of Open Access Journals (Sweden)

    Xi Wang

    2016-01-01

    Full Text Available We investigate the problem of fuzzy constrained predictive optimal control of high speed train considering the effect of actuator dynamics. The dynamics feature of the high speed train is modeled as a cascade of cars connected by flexible couplers, and the formulation is mathematically transformed into a Takagi-Sugeno (T-S fuzzy model. The goal of this study is to design a state feedback control law at each decision step to enhance safety, comfort, and energy efficiency of high speed train subject to safety constraints on the control input. Based on Lyapunov stability theory, the problem of optimizing an upper bound on the cruise control cost function subject to input constraints is reduced to a convex optimization problem involving linear matrix inequalities (LMIs. Furthermore, we analyze the influences of second-order actuator dynamics on the fuzzy constrained predictive controller, which shows risk of potentially deteriorating the overall system. Employing backstepping method, an actuator compensator is proposed to accommodate for the influence of the actuator dynamics. The experimental results show that with the proposed approach high speed train can track the desired speed, the relative coupler displacement between the neighbouring cars is stable at the equilibrium state, and the influence of actuator dynamics is reduced, which demonstrate the validity and effectiveness of the proposed approaches.

  13. Reachable Distance Space: Efficient Sampling-Based Planning for Spatially Constrained Systems

    KAUST Repository

    Xinyu Tang,

    2010-01-25

    Motion planning for spatially constrained robots is difficult due to additional constraints placed on the robot, such as closure constraints for closed chains or requirements on end-effector placement for articulated linkages. It is usually computationally too expensive to apply sampling-based planners to these problems since it is difficult to generate valid configurations. We overcome this challenge by redefining the robot\\'s degrees of freedom and constraints into a new set of parameters, called reachable distance space (RD-space), in which all configurations lie in the set of constraint-satisfying subspaces. This enables us to directly sample the constrained subspaces with complexity linear in the number of the robot\\'s degrees of freedom. In addition to supporting efficient sampling of configurations, we show that the RD-space formulation naturally supports planning and, in particular, we design a local planner suitable for use by sampling-based planners. We demonstrate the effectiveness and efficiency of our approach for several systems including closed chain planning with multiple loops, restricted end-effector sampling, and on-line planning for drawing/sculpting. We can sample single-loop closed chain systems with 1,000 links in time comparable to open chain sampling, and we can generate samples for 1,000-link multi-loop systems of varying topologies in less than a second. © 2010 The Author(s).

  14. PAPR-Constrained Pareto-Optimal Waveform Design for OFDM-STAP Radar

    Energy Technology Data Exchange (ETDEWEB)

    Sen, Satyabrata [ORNL

    2014-01-01

    We propose a peak-to-average power ratio (PAPR) constrained Pareto-optimal waveform design approach for an orthogonal frequency division multiplexing (OFDM) radar signal to detect a target using the space-time adaptive processing (STAP) technique. The use of an OFDM signal does not only increase the frequency diversity of our system, but also enables us to adaptively design the OFDM coefficients in order to further improve the system performance. First, we develop a parametric OFDM-STAP measurement model by considering the effects of signaldependent clutter and colored noise. Then, we observe that the resulting STAP-performance can be improved by maximizing the output signal-to-interference-plus-noise ratio (SINR) with respect to the signal parameters. However, in practical scenarios, the computation of output SINR depends on the estimated values of the spatial and temporal frequencies and target scattering responses. Therefore, we formulate a PAPR-constrained multi-objective optimization (MOO) problem to design the OFDM spectral parameters by simultaneously optimizing four objective functions: maximizing the output SINR, minimizing two separate Cramer-Rao bounds (CRBs) on the normalized spatial and temporal frequencies, and minimizing the trace of CRB matrix on the target scattering coefficients estimations. We present several numerical examples to demonstrate the achieved performance improvement due to the adaptive waveform design.

  15. Sensitive Constrained Optimal PMU Allocation with Complete Observability for State Estimation Solution

    Directory of Open Access Journals (Sweden)

    R. Manam

    2017-12-01

    Full Text Available In this paper, a sensitive constrained integer linear programming approach is formulated for the optimal allocation of Phasor Measurement Units (PMUs in a power system network to obtain state estimation. In this approach, sensitive buses along with zero injection buses (ZIB are considered for optimal allocation of PMUs in the network to generate state estimation solutions. Sensitive buses are evolved from the mean of bus voltages subjected to increase of load consistently up to 50%. Sensitive buses are ranked in order to place PMUs. Sensitive constrained optimal PMU allocation in case of single line and no line contingency are considered in observability analysis to ensure protection and control of power system from abnormal conditions. Modeling of ZIB constraints is included to minimize the number of PMU network allocations. This paper presents optimal allocation of PMU at sensitive buses with zero injection modeling, considering cost criteria and redundancy to increase the accuracy of state estimation solution without losing observability of the whole system. Simulations are carried out on IEEE 14, 30 and 57 bus systems and results obtained are compared with traditional and other state estimation methods available in the literature, to demonstrate the effectiveness of the proposed method.

  16. Adaptively Constrained Stochastic Model Predictive Control for the Optimal Dispatch of Microgrid

    Directory of Open Access Journals (Sweden)

    Xiaogang Guo

    2018-01-01

    Full Text Available In this paper, an adaptively constrained stochastic model predictive control (MPC is proposed to achieve less-conservative coordination between energy storage units and uncertain renewable energy sources (RESs in a microgrid (MG. Besides the economic objective of MG operation, the limits of state-of-charge (SOC and discharging/charging power of the energy storage unit are formulated as chance constraints when accommodating uncertainties of RESs, considering mild violations of these constraints are allowed during long-term operation, and a closed-loop online update strategy is performed to adaptively tighten or relax constraints according to the actual deviation probability of violation level from the desired one as well as the current change rate of deviation probability. Numerical studies show that the proposed adaptively constrained stochastic MPC for MG optimal operation is much less conservative compared with the scenario optimization based robust MPC, and also presents a better convergence performance to the desired constraint violation level than other online update strategies.

  17. Inexact Multistage Stochastic Chance Constrained Programming Model for Water Resources Management under Uncertainties

    Directory of Open Access Journals (Sweden)

    Hong Zhang

    2017-01-01

    Full Text Available In order to formulate water allocation schemes under uncertainties in the water resources management systems, an inexact multistage stochastic chance constrained programming (IMSCCP model is proposed. The model integrates stochastic chance constrained programming, multistage stochastic programming, and inexact stochastic programming within a general optimization framework to handle the uncertainties occurring in both constraints and objective. These uncertainties are expressed as probability distributions, interval with multiply distributed stochastic boundaries, dynamic features of the long-term water allocation plans, and so on. Compared with the existing inexact multistage stochastic programming, the IMSCCP can be used to assess more system risks and handle more complicated uncertainties in water resources management systems. The IMSCCP model is applied to a hypothetical case study of water resources management. In order to construct an approximate solution for the model, a hybrid algorithm, which incorporates stochastic simulation, back propagation neural network, and genetic algorithm, is proposed. The results show that the optimal value represents the maximal net system benefit achieved with a given confidence level under chance constraints, and the solutions provide optimal water allocation schemes to multiple users over a multiperiod planning horizon.

  18. Carbon-constrained scenarios. Final report

    International Nuclear Information System (INIS)

    2009-05-01

    This report provides the results of the study entitled 'Carbon-Constrained Scenarios' that was funded by FONDDRI from 2004 to 2008. The study was achieved in four steps: (i) Investigating the stakes of a strong carbon constraint for the industries participating in the study, not only looking at the internal decarbonization potential of each industry but also exploring the potential shifts of the demand for industrial products. (ii) Developing an hybrid modelling platform based on a tight dialog between the sectoral energy model POLES and the macro-economic model IMACLIM-R, in order to achieve a consistent assessment of the consequences of an economy-wide carbon constraint on energy-intensive industrial sectors, while taking into account technical constraints, barriers to the deployment of new technologies and general economic equilibrium effects. (iii) Producing several scenarios up to 2050 with different sets of hypotheses concerning the driving factors for emissions - in particular the development styles. (iv) Establishing an iterative dialog between researchers and industry representatives on the results of the scenarios so as to improve them, but also to facilitate the understanding and the appropriate use of these results by the industrial partners. This report provides the results of the different scenarios computed in the course of the project. It is a partial synthesis of the work that has been accomplished and of the numerous exchanges that this study has induced between modellers and stakeholders. The first part was written in April 2007 and describes the first reference scenario and the first mitigation scenario designed to achieve stabilization at 450 ppm CO 2 at the end of the 21. century. This scenario has been called 'mimetic' because it has been build on the assumption that the ambitious climate policy would coexist with a progressive convergence of development paths toward the current paradigm of industrialized countries: urban sprawl, general

  19. FXR agonist activity of conformationally constrained analogs of GW 4064.

    Science.gov (United States)

    Akwabi-Ameyaw, Adwoa; Bass, Jonathan Y; Caldwell, Richard D; Caravella, Justin A; Chen, Lihong; Creech, Katrina L; Deaton, David N; Madauss, Kevin P; Marr, Harry B; McFadyen, Robert B; Miller, Aaron B; Navas, Frank; Parks, Derek J; Spearing, Paul K; Todd, Dan; Williams, Shawn P; Bruce Wisely, G

    2009-08-15

    Two series of conformationally constrained analogs of the FXR agonist GW 4064 1 were prepared. Replacement of the metabolically labile stilbene with either benzothiophene or naphthalene rings led to the identification of potent full agonists 2a and 2g.

  20. Automated Precision Maneuvering and Landing in Extreme and Constrained Environments

    Data.gov (United States)

    National Aeronautics and Space Administration — Autonomous, precise maneuvering and landing in extreme and constrained environments is a key enabler for future NASA missions. Missions to map the interior of a...

  1. Security constrained optimal power flow by modern optimization tools

    African Journals Online (AJOL)

    Security constrained optimal power flow by modern optimization tools. ... International Journal of Engineering, Science and Technology ... If you would like more information about how to print, save, and work with PDFs, Highwire Press ...

  2. Slow logarithmic relaxation in models with hierarchically constrained dynamics

    OpenAIRE

    Brey, J. J.; Prados, A.

    2000-01-01

    A general kind of models with hierarchically constrained dynamics is shown to exhibit logarithmic anomalous relaxation, similarly to a variety of complex strongly interacting materials. The logarithmic behavior describes most of the decay of the response function.

  3. Synthesis of conformationally constrained peptidomimetics using multicomponent reactions

    NARCIS (Netherlands)

    Scheffelaar, R.; Klein Nijenhuis, R.A.; Paravidino, M.; Lutz, M.; Spek, A.L.; Ehlers, A.W.; de Kanter, F.J.J.; Groen, M.B.; Orru, R.V.A.; Ruijter, E.

    2009-01-01

    A novel modular synthetic approach toward constrained peptidomimetics is reported. The approach involves a highly efficient three-step sequence including two multicomponent reactions, thus allowing unprecedented diversification of both the peptide moieties and the turn-inducing scaffold. The

  4. Filter Pattern Search Algorithms for Mixed Variable Constrained Optimization Problems

    National Research Council Canada - National Science Library

    Abramson, Mark A; Audet, Charles; Dennis, Jr, J. E

    2004-01-01

    .... This class combines and extends the Audet-Dennis Generalized Pattern Search (GPS) algorithms for bound constrained mixed variable optimization, and their GPS-filter algorithms for general nonlinear constraints...

  5. Capacity Constrained Routing Algorithms for Evacuation Route Planning

    National Research Council Canada - National Science Library

    Lu, Qingsong; George, Betsy; Shekhar, Shashi

    2006-01-01

    .... In this paper, we propose a new approach, namely a capacity constrained routing planner which models capacity as a time series and generalizes shortest path algorithms to incorporate capacity constraints...

  6. Formulation of heat absorbing glasses

    Directory of Open Access Journals (Sweden)

    Álvarez-Casariego, Pedro

    1996-06-01

    Full Text Available In the thermal exchanges between buildings and environment, glazing is an element of major importance, for it largely influences the so-called Solar Heat Gain and Thermal Losses. These parameters can be modified by applying different type of coatings onto glass surface or by adding colorant compounds during glass melting. The latter is a cheaper way to control the Solar Heat Gain. The knowledge of the laws governing the interaction between colorant compounds and solar radiation, allows us to define glass formulations achieving specific aesthetic requirements and solar energy absorption. In this paper two examples of application of the modelling of glass colorants spectral absorptance are presented. First is addressed to obtaining a glass with high luminous transmittance and low solar energy transmittance, and the other one to obtaining a glass with neutral colour appearance and minimized solar energy transmittance. Calculation formulas are defined together with photometric properties so-obtained. These type of glasses are particularly suitable to be used as building and automotive glazing, for they retain the mechanical characteristics and possibilities of transformation of standard glass.

    En los intercambios de energía entre un edificio y el medio exterior, el vidrio es el elemento de mayor importancia, por su influencia en la Ganancia de Calor Solar y en las Pérdidas Térmicas. Estos parámetros pueden ser modificados mediante el depósito de capas sobre el vidrio o mediante la adición de compuestos absorbentes de la radiación solar. Esta última vía es la más económica para controlar la Ganancia de Calor Solar. El conocimiento de las leyes que gobiernan la interacción de los diversos colorantes con la radiación solar, permite definir formulaciones de vidrios con características especificas de tipo estético y de absorción energética. En este trabajo se presentan dos ejemplos de aplicación de esta modelización de las

  7. Clamped end conditions and cross section deformation in the finite element absolute nodal coordinate formulation

    International Nuclear Information System (INIS)

    Hussein, Bassam A.; Weed, David; Shabana, Ahmed A.

    2009-01-01

    In the finite element absolute nodal coordinate formulation (ANCF), the elimination of the relative translations and rotations at a point does not necessarily define a fully clamped joint, particularly in the case of fully parameterized ANCF finite elements that allow for the deformation of the cross section. In this investigation, the formulations and results of two different sets of clamped end conditions that define two different joints are compared. The first joint, called the partially clamped joint, eliminates only the translations and rotations at a point on the cross section. The second joint, called the fully clamped joint, eliminates all the translation, rotation and deformation degrees of freedom at a point on the cross section. The kinematic equations that define the partially and fully clamped joints are developed, and the dynamic equations used in the comparative numerical study presented in this paper are shown. As discussed in this investigation, the fully clamped joint does not allow for the deformation of the cross section at the joint node since the gradient vectors remain orthogonal unit vectors. The partially clamped joint, on the other hand, allows for the deformation of the cross section. Nanson's formula is used as a measure of the deformation of the cross section in the case of the partially clamped joint. A very flexible pendulum that has a rigid body attached to its free end is used to compare the results of the partially and fully clamped joints. The numerical results obtained using this very flexible pendulum example show that, while the type of joint (partially or fully clamped) does not significantly affect the gross reference motion of the system, there are fundamental differences between the two joints since the partially clamped joint allows for the cross section deformations at the joint node

  8. Fully deuterated microorganisms: Tools in magnetic resonance and neutron scattering

    International Nuclear Information System (INIS)

    Crespi, H.L.

    1988-01-01

    Current work at Argonne emphasizes the use of fully deuterated algae and cyanobacteria as tools in the study of photosynthesis and as a source of complex substrates for the culture of engineered overproducing bacteria. 17 refs., 1 fig., 1 tab

  9. Measles: Make Sure Your Child Is Fully Immunized

    Science.gov (United States)

    ... this? Submit What's this? Submit Button Past Emails Measles: Make Sure Your Child is Fully Immunized Language: ... also become infected if they are not protected. Measles in the U.S. From January 2 to March ...

  10. Fully differential cross sections for heavy particle impact ionization

    Energy Technology Data Exchange (ETDEWEB)

    McGovern, M; Walters, H R J [Department of Applied Mathematics and Theoretical Physics, Queen' s University, Belfast BT7 1NN (United Kingdom); Assafrao, D; Mohallem, J R [Laboratorio de Atomos e Moleculas Especiais, Departamento de Fisica, ICEx, Universidade Federal de Minas Gerais, P.O Box 702, 30123-970 Belo Horizonte, MG (Brazil); Whelan, Colm T, E-mail: mmcgovern06@qub.ac.u [Department of Physics, Old Dominion University, Norfolk, VA 23529-0116 (United States)

    2009-11-15

    We describe a procedure for extracting fully differential ionization cross sections from an impact parameter coupled pseudostate treatment of the collision. Some examples from antiproton impact ionization of atomic Hydrogen are given.

  11. Multi-Branch Fully Convolutional Network for Face Detection

    KAUST Repository

    Bai, Yancheng; Ghanem, Bernard

    2017-01-01

    Face detection is a fundamental problem in computer vision. It is still a challenging task in unconstrained conditions due to significant variations in scale, pose, expressions, and occlusion. In this paper, we propose a multi-branch fully

  12. Aluminum 7075-T6 fatigue data generation and probabilistic life prediction formulation

    OpenAIRE

    Kemna, John G.

    1998-01-01

    Approved for public release; distribution is unlimited. The life extension of aging fleet aircraft requires an assessment of the safe-life remaining after refurbishment. Risk can be estimated by conventional deterministic fatigue analysis coupled with a subjective factor of safety. Alternatively, risk can be quantitatively and objectively predicted by probabilistic analysis. In this investigation, a general probabilistic life formulation is specialized for constant amplitude, fully reverse...

  13. Co-grinding Effect on Crystalline Zaltoprofen with ?-cyclodextrin/Cucurbit[7]uril in Tablet Formulation

    OpenAIRE

    Li, Shanshan; Lin, Xiang; Xu, Kailin; He, Jiawei; Yang, Hongqin; Li, Hui

    2017-01-01

    This work aimed to investigate the co-grinding effects of ?-cyclodextrin (?-CD) and cucurbit[7]uril (CB[7]) on crystalline zaltoprofen (ZPF) in tablet formulation. Crystalline ZPF was prepared through anti-solvent recrystallization and fully analyzed through single-crystal X-ray diffraction. Co-ground dispersions and mono-ground ZPF were prepared using a ball grinding process. Results revealed that mono-ground ZPF slightly affected the solid state, solubility, and dissolution of crystalline Z...

  14. Constrained multi-degree reduction with respect to Jacobi norms

    KAUST Repository

    Ait-Haddou, Rachid; Barton, Michael

    2015-01-01

    We show that a weighted least squares approximation of Bézier coefficients with factored Hahn weights provides the best constrained polynomial degree reduction with respect to the Jacobi L2L2-norm. This result affords generalizations to many previous findings in the field of polynomial degree reduction. A solution method to the constrained multi-degree reduction with respect to the Jacobi L2L2-norm is presented.

  15. Clustering Using Boosted Constrained k-Means Algorithm

    Directory of Open Access Journals (Sweden)

    Masayuki Okabe

    2018-03-01

    Full Text Available This article proposes a constrained clustering algorithm with competitive performance and less computation time to the state-of-the-art methods, which consists of a constrained k-means algorithm enhanced by the boosting principle. Constrained k-means clustering using constraints as background knowledge, although easy to implement and quick, has insufficient performance compared with metric learning-based methods. Since it simply adds a function into the data assignment process of the k-means algorithm to check for constraint violations, it often exploits only a small number of constraints. Metric learning-based methods, which exploit constraints to create a new metric for data similarity, have shown promising results although the methods proposed so far are often slow depending on the amount of data or number of feature dimensions. We present a method that exploits the advantages of the constrained k-means and metric learning approaches. It incorporates a mechanism for accepting constraint priorities and a metric learning framework based on the boosting principle into a constrained k-means algorithm. In the framework, a metric is learned in the form of a kernel matrix that integrates weak cluster hypotheses produced by the constrained k-means algorithm, which works as a weak learner under the boosting principle. Experimental results for 12 data sets from 3 data sources demonstrated that our method has performance competitive to those of state-of-the-art constrained clustering methods for most data sets and that it takes much less computation time. Experimental evaluation demonstrated the effectiveness of controlling the constraint priorities by using the boosting principle and that our constrained k-means algorithm functions correctly as a weak learner of boosting.

  16. New Exact Penalty Functions for Nonlinear Constrained Optimization Problems

    Directory of Open Access Journals (Sweden)

    Bingzhuang Liu

    2014-01-01

    Full Text Available For two kinds of nonlinear constrained optimization problems, we propose two simple penalty functions, respectively, by augmenting the dimension of the primal problem with a variable that controls the weight of the penalty terms. Both of the penalty functions enjoy improved smoothness. Under mild conditions, it can be proved that our penalty functions are both exact in the sense that local minimizers of the associated penalty problem are precisely the local minimizers of the original constrained problem.

  17. Constrained multi-degree reduction with respect to Jacobi norms

    KAUST Repository

    Ait-Haddou, Rachid

    2015-12-31

    We show that a weighted least squares approximation of Bézier coefficients with factored Hahn weights provides the best constrained polynomial degree reduction with respect to the Jacobi L2L2-norm. This result affords generalizations to many previous findings in the field of polynomial degree reduction. A solution method to the constrained multi-degree reduction with respect to the Jacobi L2L2-norm is presented.

  18. Mesoporous silica formulation strategies for drug dissolution enhancement: a review.

    Science.gov (United States)

    McCarthy, Carol A; Ahern, Robert J; Dontireddy, Rakesh; Ryan, Katie B; Crean, Abina M

    2016-01-01

    Silica materials, in particular mesoporous silicas, have demonstrated excellent properties to enhance the oral bioavailability of poorly water-soluble drugs. Current research in this area is focused on investigating the kinetic profile of drug release from these carriers and manufacturing approaches to scale-up production for commercial manufacture. This review provides an overview of different methods utilized to load drugs onto mesoporous silica carriers. The influence of silica properties and silica pore architecture on drug loading and release are discussed. The kinetics of drug release from mesoporous silica systems is examined and the manufacturability and stability of these formulations are reviewed. Finally, the future prospects of mesoporous silica drug delivery systems are considered. Substantial progress has been made in the characterization and development of mesoporous drug delivery systems for drug dissolution enhancement. However, more research is required to fully understand the drug release kinetic profile from mesoporous silica materials. Incomplete drug release from the carrier and the possibility of drug re-adsorption onto the silica surface need to be investigated. Issues to be addressed include the manufacturability and regulation status of formulation approaches employing mesoporous silica to enhance drug dissolution. While more research is needed to support the move of this technology from the bench to a commercial medicinal product, it is a realistic prospect for the near future.

  19. Free vibration of fully functionally graded carbon nanotube reinforced graphite/epoxy laminates

    Science.gov (United States)

    Kuo, Shih-Yao

    2018-03-01

    This study provides the first-known vibration analysis of fully functionally graded carbon nanotube reinforced hybrid composite (FFG-CNTRHC) laminates. CNTs are non-uniformly distributed to reinforce the graphite/epoxy laminates. Some CNT distribution functions in the plane and thickness directions are proposed to more efficiently increase the stiffening effect. The rule of mixtures is modified by considering the non-homogeneous material properties of FFG-CNTRHC laminates. The formulation of the location dependent stiffness matrix and mass matrix is derived. The effects of CNT volume fraction and distribution on the natural frequencies of FFG-CNTRHC laminates are discussed. The results reveal that the FFG layout may significantly increase the natural frequencies of FFG-CNTRHC laminate.

  20. Efficient uncertainty quantification of a fully nonlinear and dispersive water wave model with random inputs

    DEFF Research Database (Denmark)

    Bigoni, Daniele; Engsig-Karup, Allan Peter; Eskilsson, Claes

    2016-01-01

    A major challenge in next-generation industrial applications is to improve numerical analysis by quantifying uncertainties in predictions. In this work we present a formulation of a fully nonlinear and dispersive potential flow water wave model with random inputs for the probabilistic description...... at different points in the parameter space, allowing for the reuse of existing simulation software. The choice of the applied methods is driven by the number of uncertain input parameters and by the fact that finding the solution of the considered model is computationally intensive. We revisit experimental...... benchmarks often used for validation of deterministic water wave models. Based on numerical experiments and assumed uncertainties in boundary data, our analysis reveals that some of the known discrepancies from deterministic simulation in comparison with experimental measurements could be partially explained...

  1. Fully-distributed randomized cooperation in wireless sensor networks

    KAUST Repository

    Bader, Ahmed

    2015-01-07

    When marrying randomized distributed space-time coding (RDSTC) to geographical routing, new performance horizons can be created. In order to reach those horizons however, routing protocols must evolve to operate in a fully distributed fashion. In this letter, we expose a technique to construct a fully distributed geographical routing scheme in conjunction with RDSTC. We then demonstrate the performance gains of this novel scheme by comparing it to one of the prominent classical schemes.

  2. Combining Semi-Endogenous and Fully Endogenous Growth: a Generalization.

    OpenAIRE

    Cozzi, Guido

    2017-01-01

    This paper shows that combining the semi-endogenous and the fully endogenous growth mechanisms with a general CES aggregator, either growth process can prevail in the balanced growth path depending on their degree of complementarity/substitutability. Policy-induced long-run economic switches to the fully endogenous steady state as the R&D employment ratio surpasses a positive threshold are possible if the two growth engines are gross substitutes.

  3. A Concept Analysis of Fully Informed: Breastfeeding Promotion

    Science.gov (United States)

    2005-12-21

    updated breastfeeding policy statement, the American Academy of Pediatrics 3 ( AAP , 2005) identified the compelling advantages of breastfeeding and urged...healthcare 4 professionals to implement principles to promote breastfeeding . The AAP cited obstacles 5 to the initiation and continuation of...Analysis of Fully Informed 2 14 A Concept Analysis of Fully Informed: Breastfeeding Promotion 15 In February 2005, the American Academy of Pediatrics ( AAP

  4. Fully-distributed randomized cooperation in wireless sensor networks

    KAUST Repository

    Bader, Ahmed; Abed-Meraim, Karim; Alouini, Mohamed-Slim

    2015-01-01

    When marrying randomized distributed space-time coding (RDSTC) to geographical routing, new performance horizons can be created. In order to reach those horizons however, routing protocols must evolve to operate in a fully distributed fashion. In this letter, we expose a technique to construct a fully distributed geographical routing scheme in conjunction with RDSTC. We then demonstrate the performance gains of this novel scheme by comparing it to one of the prominent classical schemes.

  5. Canonical operator formulation of nonequilibrium thermodynamics

    International Nuclear Information System (INIS)

    Mehrafarin, M.

    1992-09-01

    A novel formulation of nonequilibrium thermodynamics is proposed which emphasises the fundamental role played by the Boltzmann constant k in fluctuations. The equivalence of this and the stochastic formulation is demonstrated. The k → 0 limit of this theory yields the classical deterministic description of nonequilibrium thermodynamics. The new formulation possesses unique features which bear two important results namely the thermodynamic uncertainty principle and the quantisation of entropy production rate. Such a theory becomes indispensable whenever fluctuations play a significant role. (author). 7 refs

  6. Application of UV Imaging in Formulation Development

    DEFF Research Database (Denmark)

    Sun, Yu; Østergaard, Jesper

    2017-01-01

    defining formulation behavior after exposure to the aqueous environments and pharmaceutical performance is critical in pharmaceutical development, manufacturing and quality control of drugs. UV imaging has been explored as a tool for qualitative and quantitative characterization of drug dissolution...... related to the structural properties of the drug substance or formulation can be monitored. UV imaging is a non-intrusive and simple-to-operate analytical technique which holds potential for providing a mechanistic foundation for formulation development. This review aims to cover applications of UV...

  7. Formulation of 11-dimensional supergravity in superspace

    International Nuclear Information System (INIS)

    Cremmer, E.; Ferrara, S.

    1980-01-01

    We formulate on-shell 11-dimensional supergravity in superspace and express its equations of motion in terms of purely geometrical quantities. All torsion and curvature components are solved in terms of a single superfield Wsub(rstu), totally antisymmetric in its (flat vector) indices. The dimensional reduction of this formulation is expected to be related to the superspace formulation of N = 8 extended supergravity and might explain the origin of the hidden (local) SU(8) and (global) E 7 symmetries present in this theory. (orig.)

  8. An exact approach for aggregated formulations

    DEFF Research Database (Denmark)

    Gamst, Mette; Spoorendonk, Simon; Røpke, Stefan

    Aggregating formulations is a powerful approach for problems to take on tractable forms. Aggregation may lead to loss of information, i.e. the aggregated formulation may be an approximation of the original problem. In branch-and-bound context, aggregation can also complicate branching, e.g. when...... optimality cannot be guaranteed by branching on aggregated variables. We present a generic exact solution method to remedy the drawbacks of aggregation. It combines the original and aggregated formulations and applies Benders' decomposition. We apply the method to the Split Delivery Vehicle Routing Problem....

  9. Constraining the physical state by symmetries

    Science.gov (United States)

    Fatibene, L.; Ferraris, M.; Magnano, G.

    2017-03-01

    After reviewing the hole argument and its relations with initial value problem and general covariance, we shall discuss how much freedom one has to define the physical state in a generally covariant field theory (with or without internal gauge symmetries). Our analysis relies on Cauchy problems, thus it is restricted to globally hyperbolic spacetimes. We shall show that in generally covariant theories on a compact space (as well as for internal gauge symmetries on any spacetime) one has no freedom and one is forced to declare as physically equivalent two configurations which differ by a global spacetime diffeomorphism (or by an internal gauge transformation) as it is usually prescribed. On the contrary, when space is not compact, the result does not hold true and one may have different options to define physically equivalent configurations, still preserving determinism. For this scenario to be effective, the group G of formal transformations needs to be a subgroup of dynamical symmetries (otherwise field equations, which are written in terms of configurations would not induce equations for the physical state classes) and it must contain the group D generated by Cauchy transformations (otherwise the equations induced on physical state classes would not be well posed, either). We argue that it is exactly because of this double inclusion that the hole argument in its initial problem formulation is more powerful than in its boundary formulation. In the boundary formulation of the hole argument one still has that the group G of formal transformations is a subgroup of dynamical symmetries, but there is no evidence for it to contain a particular non-trivial subgroup.In this paper we shall show that this scenario is exactly implemented in generally covariant theories. In the last section we shall show it to be implemented in gauge theories as well.Norton also argued (see [1]) that the definition of physical state is something to be discussed in physics and it is not

  10. Local receptive field constrained stacked sparse autoencoder for classification of hyperspectral images.

    Science.gov (United States)

    Wan, Xiaoqing; Zhao, Chunhui

    2017-06-01

    As a competitive machine learning algorithm, the stacked sparse autoencoder (SSA) has achieved outstanding popularity in exploiting high-level features for classification of hyperspectral images (HSIs). In general, in the SSA architecture, the nodes between adjacent layers are fully connected and need to be iteratively fine-tuned during the pretraining stage; however, the nodes of previous layers further away may be less likely to have a dense correlation to the given node of subsequent layers. Therefore, to reduce the classification error and increase the learning rate, this paper proposes the general framework of locally connected SSA; that is, the biologically inspired local receptive field (LRF) constrained SSA architecture is employed to simultaneously characterize the local correlations of spectral features and extract high-level feature representations of hyperspectral data. In addition, the appropriate receptive field constraint is concurrently updated by measuring the spatial distances from the neighbor nodes to the corresponding node. Finally, the efficient random forest classifier is cascaded to the last hidden layer of the SSA architecture as a benchmark classifier. Experimental results on two real HSI datasets demonstrate that the proposed hierarchical LRF constrained stacked sparse autoencoder and random forest (SSARF) provides encouraging results with respect to other contrastive methods, for instance, the improvements of overall accuracy in a range of 0.72%-10.87% for the Indian Pines dataset and 0.74%-7.90% for the Kennedy Space Center dataset; moreover, it generates lower running time compared with the result provided by similar SSARF based methodology.

  11. Constraining neutron-star tidal Love numbers with gravitational-wave detectors

    International Nuclear Information System (INIS)

    Flanagan, Eanna E.; Hinderer, Tanja

    2008-01-01

    Ground-based gravitational wave detectors may be able to constrain the nuclear equation of state using the early, low frequency portion of the signal of detected neutron star-neutron star inspirals. In this early adiabatic regime, the influence of a neutron star's internal structure on the phase of the waveform depends only on a single parameter λ of the star related to its tidal Love number, namely, the ratio of the induced quadrupole moment to the perturbing tidal gravitational field. We analyze the information obtainable from gravitational wave frequencies smaller than a cutoff frequency of 400 Hz, where corrections to the internal-structure signal are less than 10%. For an inspiral of two nonspinning 1.4M · neutron stars at a distance of 50 Megaparsecs, LIGO II detectors will be able to constrain λ to λ≤2.0x10 37 g cm 2 s 2 with 90% confidence. Fully relativistic stellar models show that the corresponding constraint on radius R for 1.4M · neutron stars would be R≤13.6 km (15.3 km) for a n=0.5 (n=1.0) polytrope with equation of state p∝ρ 1+1/n

  12. Helium atom in a box: a fully quantal solution

    Energy Technology Data Exchange (ETDEWEB)

    Mitnik, D.M. [Departmento de Fisica, FCEyN, Universidad de Buenos Aires, and Instituto de Astronomia y Fisica del Espacio (IAFE), Casilla de Correo 67, Sucursal 28 (C1428EGA) Buenos Aires (Argentina)

    2007-06-15

    A complete non-perturbative solution of the Helium atom in a box problem is presented by developing two numerical techniques. The first technique is the direct solution by diagonalization of the Hamiltonian, and the second is based on a constrained relaxation of the wave functions. Time-dependent propagation of doubly-excited wave-functions is analyzed, allowing the calculation and the visualization of the autoionization process.

  13. A constrained robust least squares approach for contaminant release history identification

    Science.gov (United States)

    Sun, Alexander Y.; Painter, Scott L.; Wittmeyer, Gordon W.

    2006-04-01

    Contaminant source identification is an important type of inverse problem in groundwater modeling and is subject to both data and model uncertainty. Model uncertainty was rarely considered in the previous studies. In this work, a robust framework for solving contaminant source recovery problems is introduced. The contaminant source identification problem is first cast into one of solving uncertain linear equations, where the response matrix is constructed using a superposition technique. The formulation presented here is general and is applicable to any porous media flow and transport solvers. The robust least squares (RLS) estimator, which originated in the field of robust identification, directly accounts for errors arising from model uncertainty and has been shown to significantly reduce the sensitivity of the optimal solution to perturbations in model and data. In this work, a new variant of RLS, the constrained robust least squares (CRLS), is formulated for solving uncertain linear equations. CRLS allows for additional constraints, such as nonnegativity, to be imposed. The performance of CRLS is demonstrated through one- and two-dimensional test problems. When the system is ill-conditioned and uncertain, it is found that CRLS gave much better performance than its classical counterpart, the nonnegative least squares. The source identification framework developed in this work thus constitutes a reliable tool for recovering source release histories in real applications.

  14. The Rate-Controlled Constrained-Equilibrium Approach to Far-From-Local-Equilibrium Thermodynamics

    Directory of Open Access Journals (Sweden)

    Hameed Metghalchi

    2012-01-01

    Full Text Available The Rate-Controlled Constrained-Equilibrium (RCCE method for the description of the time-dependent behavior of dynamical systems in non-equilibrium states is a general, effective, physically based method for model order reduction that was originally developed in the framework of thermodynamics and chemical kinetics. A generalized mathematical formulation is presented here that allows including nonlinear constraints in non-local equilibrium systems characterized by the existence of a non-increasing Lyapunov functional under the system’s internal dynamics. The generalized formulation of RCCE enables to clarify the essentials of the method and the built-in general feature of thermodynamic consistency in the chemical kinetics context. In this paper, we work out the details of the method in a generalized mathematical-physics framework, but for definiteness we detail its well-known implementation in the traditional chemical kinetics framework. We detail proofs and spell out explicit functional dependences so as to bring out and clarify each underlying assumption of the method. In the standard context of chemical kinetics of ideal gas mixtures, we discuss the relations between the validity of the detailed balance condition off-equilibrium and the thermodynamic consistency of the method. We also discuss two examples of RCCE gas-phase combustion calculations to emphasize the constraint-dependent performance of the RCCE method.

  15. Chemical-Based Formulation Design: Virtual Experimentation

    DEFF Research Database (Denmark)

    Conte, Elisa; Gani, Rafiqul

    This paper presents a software, the virtual Product-Process Design laboratory (virtual PPD-lab) and the virtual experimental scenarios for design/verification of consumer oriented liquid formulated products where the software can be used. For example, the software can be employed for the design......, the additives and/or their mixtures (formulations). Therefore, the experimental resources can focus on a few candidate product formulations to find the best product. The virtual PPD-lab allows various options for experimentations related to design and/or verification of the product. For example, the selection...... design, model adaptation). All of the above helps to perform virtual experiments by blending chemicals together and observing their predicted behaviour. The paper will highlight the application of the virtual PPD-lab in the design and/or verification of different consumer products (paint formulation...

  16. Understanding Pesticide Risks: Toxicity and Formulation

    OpenAIRE

    Muntz, Helen; Miller, Rhonda; Alston, Diane

    2016-01-01

    This fact sheet provides information about pesticide risks to human health, primary means of pesticide exposure, standardized measures of pesticide toxicity, pesticide signal words and type of pesticide formulations.

  17. Emulsifying Formulation of Rosuvastatin Calcium for Improved ...

    African Journals Online (AJOL)

    solubility study, liquid formulations were prepared using LAS/Capryol 90: Maisine 35-1 as oil phase and. Tween 20 with ... evaluated for globule size, zeta potential, and emulsion properties. ..... surfactants which decreases the electrostatic.

  18. Drug Nanoparticle Formulation Using Ascorbic Acid Derivatives

    Directory of Open Access Journals (Sweden)

    Kunikazu Moribe

    2011-01-01

    Full Text Available Drug nanoparticle formulation using ascorbic acid derivatives and its therapeutic uses have recently been introduced. Hydrophilic ascorbic acid derivatives such as ascorbyl glycoside have been used not only as antioxidants but also as food and pharmaceutical excipients. In addition to drug solubilization, drug nanoparticle formation was observed using ascorbyl glycoside. Hydrophobic ascorbic acid derivatives such as ascorbyl mono- and di-n-alkyl fatty acid derivatives are used either as drugs or carrier components. Ascorbyl n-alkyl fatty acid derivatives have been formulated as antioxidants or anticancer drugs for nanoparticle formulations such as micelles, microemulsions, and liposomes. ASC-P vesicles called aspasomes are submicron-sized particles that can encapsulate hydrophilic drugs. Several transdermal and injectable formulations of ascorbyl n-alkyl fatty acid derivatives were used, including ascorbyl palmitate.

  19. Dynamic psychiatry and the psychodynamic formulation

    African Journals Online (AJOL)

    processes and psychiatric disorders are biological, the range ... The formulation furthermore helps with the initial orientation towards the patient: it anticipates and predicts how the patient ..... contributed to problems with his sexual identity.

  20. Formulation of Thermosensitive Hydrogel Containing Cyclodextrin ...

    African Journals Online (AJOL)

    Materials. Chitosan (deacetylation degree, DDA = 80 %) was obtained from HiMedia Laboratories Pvt. ... Sterile formulations were ... Chilled β-GP aqueous solution (sterilized through ..... generally decreasing away from the center of the tumor.

  1. Current advances on polynomial resultant formulations

    Science.gov (United States)

    Sulaiman, Surajo; Aris, Nor'aini; Ahmad, Shamsatun Nahar

    2017-08-01

    Availability of computer algebra systems (CAS) lead to the resurrection of the resultant method for eliminating one or more variables from the polynomials system. The resultant matrix method has advantages over the Groebner basis and Ritt-Wu method due to their high complexity and storage requirement. This paper focuses on the current resultant matrix formulations and investigates their ability or otherwise towards producing optimal resultant matrices. A determinantal formula that gives exact resultant or a formulation that can minimize the presence of extraneous factors in the resultant formulation is often sought for when certain conditions that it exists can be determined. We present some applications of elimination theory via resultant formulations and examples are given to explain each of the presented settings.

  2. Formulation and Characterization of Biodegradable Medicated ...

    African Journals Online (AJOL)

    PEG)-600, tributyl citrate, PEG-200, PEG-300, PEG-400, PEG-4000, triethyl citrate and castor oil. The gum formulations were characterized for the following parameters: texture profile analysis (TPA), biodegradation, in vitro drug release using a ...

  3. A simplectic formulation of relativistic particle dynamics

    International Nuclear Information System (INIS)

    Tulczyjew, W.M.

    1976-12-01

    Particle mechanics is formulated in terms of symplectic relations and infinitesimal symplectic relations. Generating functions of symplectic relations are shown to be classical counterparts of Green's functions of wave mechanics. (orig.) [de

  4. A sympletic formulation of relativistic particle dynamics

    International Nuclear Information System (INIS)

    Tulczyjew, W.M.

    1977-01-01

    Particle mechanics is formulated in terms of sympletic relations and infinitesimal symplectic relations. Generating functions of symplectic relations are shown to be classical counterparts of Green's functions of wave mechanics. (author)

  5. Paclitaxel Albumin-stabilized Nanoparticle Formulation

    Science.gov (United States)

    This page contains brief information about paclitaxel albumin-stabilized nanoparticle formulation and a collection of links to more information about the use of this drug, research results, and ongoing clinical trials.

  6. The Boltzmann equation in the difference formulation

    Energy Technology Data Exchange (ETDEWEB)

    Szoke, Abraham [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Brooks III, Eugene D. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

    2015-05-06

    First we recall the assumptions that are needed for the validity of the Boltzmann equation and for the validity of the compressible Euler equations. We then present the difference formulation of these equations and make a connection with the time-honored Chapman - Enskog expansion. We discuss the hydrodynamic limit and calculate the thermal conductivity of a monatomic gas, using a simplified approximation for the collision term. Our formulation is more consistent and simpler than the traditional derivation.

  7. Limitations of high dose carrier based formulations.

    Science.gov (United States)

    Yeung, Stewart; Traini, Daniela; Tweedie, Alan; Lewis, David; Church, Tanya; Young, Paul M

    2018-06-10

    This study was performed to investigate how increasing the active pharmaceutical ingredient (API) content within a formulation affects the dispersion of particles and the aerosol performance efficiency of a carrier based dry powder inhalable (DPI) formulation, using a custom dry powder inhaler (DPI) development rig. Five formulations with varying concentrations of API beclomethasone dipropionate (BDP) between 1% and 30% (w/w) were formulated as a multi-component carrier system containing coarse lactose and fine lactose with magnesium stearate. The morphology of the formulation and each component were investigated using scanning electron micrographs while the particle size was measured by laser diffraction. The aerosol performance, in terms of aerodynamic diameter, was assessed using the British pharmacopeia Apparatus E cascade impactor (Next generation impactor). Chemical analysis of the API was observed by high performance liquid chromatography (HPLC). Increasing the concentration of BDP in the blend resulted in increasing numbers and size of individual agglomerates and densely packed BDP multi-layers on the surface of the lactose carrier. BDP present within the multi-layer did not disperse as individual primary particles but as dense agglomerates, which led to a decrease in aerosol performance and increased percentage of BDP deposition within the Apparatus E induction port and pre-separator. As the BDP concentration in the blends increases, aerosol performance of the formulation decreases, in an inversely proportional manner. Concurrently, the percentage of API deposition in the induction port and pre-separator could also be linked to the amount of micronized particles (BDP and Micronized composite carrier) present in the formulation. The effect of such dose increase on the behaviour of aerosol dispersion was investigated to gain greater insight in the development and optimisation of higher dosed carrier-based formulations. Copyright © 2018 Elsevier B.V. All

  8. Chemicals-Based Formulation Design: Virtual Experimentations

    DEFF Research Database (Denmark)

    Conte, Elisa; Gani, Rafiqul

    2011-01-01

    This paper presents a systematic procedure for virtual experimentations related to the design of liquid formulated products. All the experiments that need to be performed when designing a liquid formulated product (lotion), such as ingredients selection and testing, solubility tests, property mea...... on the design of an insect repellent lotion will show that the software is an essential instrument in decision making, and that it reduces time and resources since experimental efforts can be focused on one or few product alternatives....

  9. Comments on alternate formulations for preequilibrium decay

    International Nuclear Information System (INIS)

    Blann, M.

    1978-01-01

    The physical and mathematical differences of several formulations for preequilibrium decay are discussed. Mathematical models and examples are presented or referred to in order to illustrate what the author believes to be errors in the exciton formulation as being due to improper inclusion of spectator effects. An earlier work of Gadioli et al. is reinterpreted, and quotations therein to work of the present author are corrected

  10. Fully coupled heat conduction and deformation analyses of visco-elastic solids

    KAUST Repository

    Khan, Kamran

    2012-04-21

    Visco-elastic materials are known for their capability of dissipating energy. This energy is converted into heat and thus changes the temperature of the materials. In addition to the dissipation effect, an external thermal stimulus can also alter the temperature in a viscoelastic body. The rate of stress relaxation (or the rate of creep) and the mechanical and physical properties of visco-elastic materials, such as polymers, vary with temperature. This study aims at understanding the effect of coupling between the thermal and mechanical response that is attributed to the dissipation of energy, heat conduction, and temperature-dependent material parameters on the overall response of visco-elastic solids. The non-linearly viscoelastic constitutive model proposed by Schapery (Further development of a thermodynamic constitutive theory: stress formulation, 1969,Mech. Time-Depend. Mater. 1:209-240, 1997) is used and modified to incorporate temperature- and stress-dependent material properties. This study also formulates a non-linear energy equation along with a dissipation function based on the Gibbs potential of Schapery (Mech. Time-Depend. Mater. 1:209-240, 1997). A numerical algorithm is formulated for analyzing a fully coupled thermo-visco-elastic response and implemented it in a general finite-element (FE) code. The non-linear stress- and temperature-dependent material parameters are found to have significant effects on the coupled thermo-visco-elastic response of polymers considered in this study. In order to obtain a realistic temperature field within the polymer visco-elastic bodies undergoing a non-uniform heat generation, the role of heat conduction cannot be ignored. © Springer Science+Business Media, B. V. 2012.

  11. The coevent formulation of quantum theory

    International Nuclear Information System (INIS)

    Wallden, Petros

    2013-01-01

    Understanding quantum theory has been a subject of debate from its birth. Many different formulations and interpretations have been proposed. Here we examine a recent novel formulation, namely the coevents formulation. It is a histories formulation and has as starting point the Feynman path integral and the decoherence functional. The new ontology turns out to be that of a coarse-grained history. We start with a quantum measure defined on the space of histories, and the existence of zero covers rules out single-history as potential reality (the Kochen Specker theorem casted in histories form is a special case of a zero cover). We see that allowing coarse-grained histories as potential realities avoids the previous paradoxes, maintains deductive non-contextual logic (alas non-Boolean) and gives rise to a unique classical domain. Moreover, we can recover the probabilistic predictions of quantum theory with the use of the Cournot's principle. This formulation, being both a realist formulation and based on histories, is well suited conceptually for the purposes of quantum gravity and cosmology.

  12. An herbal formulation for hemorrhoids treatment

    Directory of Open Access Journals (Sweden)

    S. Dehdari

    2017-11-01

    Full Text Available Background and objectives: Hemorrhoids is the most painful rectal disease. Straining and pregnancy seem playing chief roles in the development of hemorrhoids. Symptoms of hemorrhoids may include bleeding, inflammation and pain. Despite current medical efforts, many discomforts of hemorrhoids have not been handled. The aim of the present study was to formulate and evaluate Itrifal-e muqil (IM tablet to achieve desired pharmaceutical properties. Method: Quality control tests of Allium ampeloperasum L, Commiphora mukul (Hook. ex Stocks Engl., Phyllanthus emblica L., Terminalia chebula Retz. and Terminalia bellerica Retz. were performed. Afterwards, different formulations were prepared and their physical properties were evaluated. Subsequently, the formulation was coated and its physicochemical characteristics were assessed. Result: All of the herbs demonstrated good results in quality control tests according to United State Pharmacopeia (USP. Formulation-1 that was completely prepared based on explained manufacturing process of IM in traditional medicine manuscripts did not show suitable pharmaceutical properties. Among different formulations, Formulation-3 that consisted of A. ampeloperasum, C. mukul, P. emblica, T. chebula and T. bellerica, displayed best outcomes through different tests. Conclusion: Modern pharmaceutical approaches can excellently be adapted for IM preparations.

  13. Gauge stability of 3+1 formulations of general relativity

    International Nuclear Information System (INIS)

    Khokhlov, A M; Novikov, I D

    2002-01-01

    We present a general approach to the analysis of gauge stability of 3+1 formulations of general relativity (GR). Evolution of coordinate perturbations and the corresponding perturbations of lapse and shift can be described by a system of eight quasi-linear partial differential equations. Stability with respect to gauge perturbations depends on the choice of gauge and a background metric, but it does not depend on a particular form of a 3+1 system if its constrained solutions are equivalent to those of the Einstein equations. Stability of a number of known gauges is investigated in the limit of short-wavelength perturbations. All fixed gauges except a synchronous gauge are found to be ill posed. A maximal slicing gauge and its parabolic extension are shown to be ill posed as well. A necessary condition is derived for well-posedness of metric-dependent algebraic gauges. Well-posed metric-dependent gauges are found, however, to be generally unstable. Both instability and ill-posedness are associated with the existence of growing modes of coordinate perturbations related to perturbations of physical accelerations of reference frames

  14. Fully coupled thermal-mechanical-fluid flow model for nonliner geologic systems

    International Nuclear Information System (INIS)

    Hart, R.D.

    1981-01-01

    A single model is presented which describes fully coupled thermal-mechanical-fluid flow behavior of highly nonlinear, dynamic or quasistatic, porous geologic systems. The mathematical formulation for the model utilizes the continuum theory of mixtures to describe the multiphase nature of the system, and incremental linear constitutive theory to describe the path dependency of nonlinear material behavior. The model, incorporated in an explicit finite difference numerical procedure, was implemented in two different computer codes. A special-purpose one-dimensional code, SNEAKY, was written for initial validation of the coupling mechanisms and testing of the coupled model logic. A general purpose commercially available code, STEALTH, developed for modeling dynamic nonlinear thermomechanical processes, was modified to include fluid flow behavior and the coupling constitutive model. The fully explicit approach in the coupled calculation facilitated the inclusion of the coupling mechanisms and complex constitutive behavior. Analytical solutions pertaining to consolidation theory for soils, thermoelasticity for solids, and hydrothermal convection theory provided verification of stress and fluid flow, stress and conductive heat transfer, and heat transfer and fluid flow couplings, respectively, in the coupled model. A limited validation of the adequacy of the coupling constitutive assumptions was also performed by comparison with the physical response from two laboratory tests. Finally, the full potential of the coupled model is illustrated for geotechnical applications in energy-resource related areas. Examples in the areas of nuclear waste isolation and cut-and-fill mining are cited

  15. Ignition delay measurements of light naphtha: A fully blended low octane fuel

    KAUST Repository

    Javed, Tamour

    2016-06-15

    Light naphtha is a fully blended, low-octane (RON. = 64.5, MON. = 63.5), highly paraffinic (>. 90% paraffinic content) fuel, and is one of the first distillates obtained during the crude oil refining process. Light naphtha is an attractive low-cost fuel candidate for advanced low-temperature compression ignition engines where autoignition is the primary control mechanism. We measured ignition delay times for light naphtha in a shock tube and a rapid compression machine (RCM) over a broad range of temperatures (640-1250. K), pressures (20 and 40. bar) and equivalence ratios (0.5, 1 and 2). Ignition delay times were modeled using a two-component primary reference fuel (PRF) surrogate and a multi-component surrogate. Both surrogates adequately captured the measured ignition delay times of light naphtha under shock tube conditions. However, for low-temperature RCM conditions, simulations with the multi-component surrogate showed better agreement with experimental data. These simulated surrogate trends were confirmed by measuring the ignition delay times of the PRF and multi-component surrogates in the RCM at . P = 20. bar, . ϕ = 2. Detailed kinetic analyses were undertaken to ascertain the dependence of the surrogates\\' reactivity on their chemical composition. To the best of our knowledge, this is the first fundamental autoignition study on the reactivity of a low-octane fully blended fuel and the use of a suitably formulated multi-component surrogate to model its behavior.

  16. Convex Relaxations of Chance Constrained AC Optimal Power Flow

    DEFF Research Database (Denmark)

    Venzke, Andreas; Halilbasic, Lejla; Markovic, Uros

    2017-01-01

    , reactive power, and voltage. We state a tractable formulation for two types of uncertainty sets. Using a scenario-based approach and making no prior assumptions about the probability distribution of the forecast errors, we obtain a robust formulation for a rectangular uncertainty set. Alternatively...

  17. Problem formulation for risk assessment of combined exposures to chemicals and other stressors in humans.

    Science.gov (United States)

    Solomon, Keith R; Wilks, Martin F; Bachman, Ammie; Boobis, Alan; Moretto, Angelo; Pastoor, Timothy P; Phillips, Richard; Embry, Michelle R

    2016-11-01

    When the human health risk assessment/risk management paradigm was developed, it did not explicitly include a "problem formulation" phase. The concept of problem formulation was first introduced in the context of ecological risk assessment (ERA) for the pragmatic reason to constrain and focus ERAs on the key questions. However, this need also exists for human health risk assessment, particularly for cumulative risk assessment (CRA), because of its complexity. CRA encompasses the combined threats to health from exposure via all relevant routes to multiple stressors, including biological, chemical, physical and psychosocial stressors. As part of the HESI Risk Assessment in the 21st Century (RISK21) Project, a framework for CRA was developed in which problem formulation plays a critical role. The focus of this effort is primarily on a chemical CRA (i.e., two or more chemicals) with subsequent consideration of non-chemical stressors, defined as "modulating factors" (ModFs). Problem formulation is a systematic approach that identifies all factors critical to a specific risk assessment and considers the purpose of the assessment, scope and depth of the necessary analysis, analytical approach, available resources and outcomes, and overall risk management goal. There are numerous considerations that are specific to multiple stressors, and proper problem formulation can help to focus a CRA to the key factors in order to optimize resources. As part of the problem formulation, conceptual models for exposures and responses can be developed that address these factors, such as temporal relationships between stressors and consideration of the appropriate ModFs.

  18. Global fully kinetic models of planetary magnetospheres with iPic3D

    Science.gov (United States)

    Gonzalez, D.; Sanna, L.; Amaya, J.; Zitz, A.; Lembege, B.; Markidis, S.; Schriver, D.; Walker, R. J.; Berchem, J.; Peng, I. B.; Travnicek, P. M.; Lapenta, G.

    2016-12-01

    We report on the latest developments of our approach to model planetary magnetospheres, mini magnetospheres and the Earth's magnetosphere with the fully kinetic, electromagnetic particle in cell code iPic3D. The code treats electrons and multiple species of ions as full kinetic particles. We review: 1) Why a fully kinetic model and in particular why kinetic electrons are needed for capturing some of the most important aspects of the physics processes of planetary magnetospheres. 2) Why the energy conserving implicit method (ECIM) in its newest implementation [1] is the right approach to reach this goal. We consider the different electron scales and study how the new IECIM can be tuned to resolve only the electron scales of interest while averaging over the unresolved scales preserving their contribution to the evolution. 3) How with modern computing planetary magnetospheres, mini magnetosphere and eventually Earth's magnetosphere can be modeled with fully kinetic electrons. The path from petascale to exascale for iPiC3D is outlined based on the DEEP-ER project [2], using dynamic allocation of different processor architectures (Xeon and Xeon Phi) and innovative I/O technologies.Specifically results from models of Mercury are presented and compared with MESSENGER observations and with previous hybrid (fluid electrons and kinetic ions) simulations. The plasma convection around the planets includes the development of hydrodynamic instabilities at the flanks, the presence of the collisionless shocks, the magnetosheath, the magnetopause, reconnection zones, the formation of the plasma sheet and the magnetotail, and the variation of ion/electron plasma flows when crossing these frontiers. Given the full kinetic nature of our approach we focus on detailed particle dynamics and distribution at locations that can be used for comparison with satellite data. [1] Lapenta, G. (2016). Exactly Energy Conserving Implicit Moment Particle in Cell Formulation. arXiv preprint ar

  19. A Support Vector Learning-Based Particle Filter Scheme for Target Localization in Communication-Constrained Underwater Acoustic Sensor Networks.

    Science.gov (United States)

    Li, Xinbin; Zhang, Chenglin; Yan, Lei; Han, Song; Guan, Xinping

    2017-12-21

    Target localization, which aims to estimate the location of an unknown target, is one of the key issues in applications of underwater acoustic sensor networks (UASNs). However, the constrained property of an underwater environment, such as restricted communication capacity of sensor nodes and sensing noises, makes target localization a challenging problem. This paper relies on fractional sensor nodes to formulate a support vector learning-based particle filter algorithm for the localization problem in communication-constrained underwater acoustic sensor networks. A node-selection strategy is exploited to pick fractional sensor nodes with short-distance pattern to participate in the sensing process at each time frame. Subsequently, we propose a least-square support vector regression (LSSVR)-based observation function, through which an iterative regression strategy is used to deal with the distorted data caused by sensing noises, to improve the observation accuracy. At the same time, we integrate the observation to formulate the likelihood function, which effectively update the weights of particles. Thus, the particle effectiveness is enhanced to avoid "particle degeneracy" problem and improve localization accuracy. In order to validate the performance of the proposed localization algorithm, two different noise scenarios are investigated. The simulation results show that the proposed localization algorithm can efficiently improve the localization accuracy. In addition, the node-selection strategy can effectively select the subset of sensor nodes to improve the communication efficiency of the sensor network.

  20. Constrained Local UniversE Simulations: a Local Group factory

    Science.gov (United States)

    Carlesi, Edoardo; Sorce, Jenny G.; Hoffman, Yehuda; Gottlöber, Stefan; Yepes, Gustavo; Libeskind, Noam I.; Pilipenko, Sergey V.; Knebe, Alexander; Courtois, Hélène; Tully, R. Brent; Steinmetz, Matthias

    2016-05-01

    Near-field cosmology is practised by studying the Local Group (LG) and its neighbourhood. This paper describes a framework for simulating the `near field' on the computer. Assuming the Λ cold dark matter (ΛCDM) model as a prior and applying the Bayesian tools of the Wiener filter and constrained realizations of Gaussian fields to the Cosmicflows-2 (CF2) survey of peculiar velocities, constrained simulations of our cosmic environment are performed. The aim of these simulations is to reproduce the LG and its local environment. Our main result is that the LG is likely a robust outcome of the ΛCDMscenario when subjected to the constraint derived from CF2 data, emerging in an environment akin to the observed one. Three levels of criteria are used to define the simulated LGs. At the base level, pairs of haloes must obey specific isolation, mass and separation criteria. At the second level, the orbital angular momentum and energy are constrained, and on the third one the phase of the orbit is constrained. Out of the 300 constrained simulations, 146 LGs obey the first set of criteria, 51 the second and 6 the third. The robustness of our LG `factory' enables the construction of a large ensemble of simulated LGs. Suitable candidates for high-resolution hydrodynamical simulations of the LG can be drawn from this ensemble, which can be used to perform comprehensive studies of the formation of the LG.

  1. Fully hadronic ttbar cross section measurement with ATLAS detector

    CERN Document Server

    Bertella, C; The ATLAS collaboration

    2011-01-01

    The top quark pair production cross section in the fully hadronic final state is characterized by a six jet topology, two of which could be identified as originating from a b-quark using ATLAS b-tagging algorithms. Compared to other decay channels, this final state presents an advantageous larger branching ratio; on the other hand it suffers from a very large QCD multi-jet background, generally difficult to estimate from Monte Carlo simulation and therefore evaluated using data-driven techniques. It is essential, to efficiently trigger on these fully hadronic ttbar events, to use dedicated triggers. An overview of the analysis for ttbar production cross section measurement in the fully hadronic final state and the state-of-the-art of the b-jet trigger performance estimation are presented in this contribution.

  2. Fully kinetic simulations of megajoule-scale dense plasma focus

    Energy Technology Data Exchange (ETDEWEB)

    Schmidt, A.; Link, A.; Tang, V.; Halvorson, C.; May, M. [Lawrence Livermore National Laboratory, Livermore California 94550 (United States); Welch, D. [Voss Scientific, LLC, Albuquerque, New Mexico 87108 (United States); Meehan, B. T.; Hagen, E. C. [National Security Technologies, LLC, Las Vegas, Nevada 89030 (United States)

    2014-10-15

    Dense plasma focus (DPF) Z-pinch devices are sources of copious high energy electrons and ions, x-rays, and neutrons. Megajoule-scale DPFs can generate 10{sup 12} neutrons per pulse in deuterium gas through a combination of thermonuclear and beam-target fusion. However, the details of the neutron production are not fully understood and past optimization efforts of these devices have been largely empirical. Previously, we reported on the first fully kinetic simulations of a kilojoule-scale DPF and demonstrated that both kinetic ions and kinetic electrons are needed to reproduce experimentally observed features, such as charged-particle beam formation and anomalous resistivity. Here, we present the first fully kinetic simulation of a MegaJoule DPF, with predicted ion and neutron spectra, neutron anisotropy, neutron spot size, and time history of neutron production. The total yield predicted by the simulation is in agreement with measured values, validating the kinetic model in a second energy regime.

  3. Fully plastic solutions of semi-elliptical surface cracks

    International Nuclear Information System (INIS)

    Yagawa, Genki; Yoshimura, Shinobu; Kitajima, Yasumi; Ueda, Hiroyoshi.

    1990-01-01

    Nonlinear finite element analyses of semi-elliptical surface cracks are performed under the fully plastic condition. The power-law hardening materials and the deformation theory of plasticity are assumed. Either the penalty function method or the Uzawa's algorithm is utilized to treat the incompressibility of plastic strains. The local and global J-integral values are obtained using a virtual crack extension technique for plates and cylinders with semi-elliptical surface cracks subjected to uniform tensions. The fully plastic solutions for surface cracked plates are given in the form of polynominals with geometric parameters a/t, a/c and the strain hardening exponent (n). In addition, the effects of curvature on fully plastic solutions are discussed through the comparison between the results of plates and cylinders. (author)

  4. CMOS serial link for fully duplexed data communication

    Science.gov (United States)

    Lee, Kyeongho; Kim, Sungjoon; Ahn, Gijung; Jeong, Deog-Kyoon

    1995-04-01

    This paper describes a CMOS serial link allowing fully duplexed 500 Mbaud serial data communication. The CMOS serial link is a robust and low-cost solution to high data rate requirements. A central charge pump PLL for generating multiphase clocks for oversampling is shared by several serial link channels. Fully duplexed serial data communication is realized in the bidirectional bridge by separating incoming data from the mixed signal on the cable end. The digital PLL accomplishes process-independent data recovery by using a low-ratio oversampling, a majority voting, and a parallel data recovery scheme. Mostly, digital approach could extend its bandwidth further with scaled CMOS technology. A single channel serial link and a charge pump PLL are integrated in a test chip using 1.2 micron CMOS process technology. The test chip confirms upto 500 Mbaud unidirectional mode operation and 320 Mbaud fully duplexed mode operation with pseudo random data patterns.

  5. Fully developed turbulence via Feigenbaum's period-doubling bifurcations

    International Nuclear Information System (INIS)

    Duong-van, M.

    1987-08-01

    Since its publication in 1978, Feigenbaum's predictions of the onset of turbulence via period-doubling bifurcations have been thoroughly borne out experimentally. In this paper, Feigenbaum's theory is extended into the regime in which we expect to see fully developed turbulence. We develop a method of averaging that imposes correlations in the fluctuating system generated by this map. With this averaging method, the field variable is obtained by coarse-graining, while microscopic fluctuations are preserved in all averaging scales. Fully developed turbulence will be shown to be a result of microscopic fluctuations with proper averaging. Furthermore, this model preserves Feigenbaum's results on the physics of bifurcations at the onset of turbulence while yielding additional physics both at the onset of turbulence and in the fully developed turbulence regime

  6. Formulation studies for mirtazapine orally disintegrating tablets.

    Science.gov (United States)

    Yıldız, Simay; Aytekin, Eren; Yavuz, Burçin; Bozdağ Pehlivan, Sibel; Ünlü, Nurşen

    2016-01-01

    Orally disintegrating tablets (ODTs) recently have gained much attention to fulfill the needs for pediatric, geriatric, and psychiatric patients with dysphagia. Aim of this study was to develop new ODT formulations containing mirtazapine, an antidepressant drug molecule having bitter taste, by using simple and inexpensive preparation methods such as coacervation, direct compression and to compare their characteristics with those of reference product (Remereon SolTab). Coacervation method was chosen for taste masking of mirtazapine. In vitro characterization studies such as diameter and thickness, weight variation, tablet hardness, tablet friability and disintegration time were performed on tablet formulations. Wetting time and in vitro dissolution tests of developed ODTs also studied using 900 mL 0.1 N HCl medium, 900 mL pH 6.8 phosphate buffer or 900 mL pH 4.5 acetate buffer at 37 ± 0.2 °C as dissolution medium. Ratio of Eudragit® E-100 was chosen as 6% (w/w) since the dissolution profile of A1 (6% Eudragit® E-100) was found closer to the reference product than A2 (4% Eudragit® E-100) and A3 (8% Eudragit® E-100). Group D, E and F formulations were presented better results in terms of disintegration time. Dissolution results indicated that Group E and F formulations showed optimum properties in all three dissolution media. Formulations D1, D4, D5, E3, E4, F1 and F5 found suitable as ODT formulations due to their favorable disintegration times and dissolution profiles. Developed mirtazapine ODTs were found promising in terms of showing the similar characteristics to the original formulation.

  7. TURVA-2012: Formulation of radionuclide release scenarios

    International Nuclear Information System (INIS)

    Marcos, Nuria; Hjerpe, Thomas; Snellman, Margit; Ikonen, Ari; Smith, Paul

    2014-01-01

    TURVA-2012 is Posiva's safety case in support of the Preliminary Safety Analysis Report (PSAR) and application for a construction licence for a repository for disposal of spent nuclear fuel at the Olkiluoto site in south-western Finland. This paper gives a summary of the scenarios and the methodology followed in formulating them as described in TURVA-2012: Formulation of Radionuclide Release Scenarios (Posiva, 2013). The scenarios are further analysed in TURVA-2012: Assessment of Radionuclide Release Scenarios for the Repository System and TURVA-2012: Biosphere Assessment (Posiva, 2012a, 2012b). The formulation of scenarios takes into account the safety functions of the main barriers of the repository system and the uncertainties in the features, events, and processes (FEP) that may affect the entire disposal system (i.e. repository system plus the surface environment) from the emplacement of the first canister until the far future. In the report TURVA-2012: Performance Assessment (2012d), the performance of the engineered and natural barriers has been assessed against the loads expected during the evolution of the repository system and the site. Uncertainties have been identified and these are taken into account in the formulation of radionuclide release scenarios. The uncertainties in the FEP and evolution of the surface environment are taken into account in formulating the surface environment scenarios used ultimately in estimating radiation exposure. Formulating radionuclide release scenarios for the repository system links the reports Performance Assessment and Assessment of Radionuclide Release Scenarios for the Repository System. The formulation of radionuclide release scenarios for the surface environment brings together biosphere description and the surface environment FEP and is the link to the assessment of the surface environment scenarios summarised in TURVA-2012: Biosphere Assessment. (authors)

  8. A Fully Implantable, NFC Enabled, Continuous Interstitial Glucose Monitor

    OpenAIRE

    Anabtawi, Nijad; Freeman, Sabrina; Ferzli, Rony

    2016-01-01

    This work presents an integrated system-on-chip (SoC) that forms the core of a long-term, fully implantable, battery assisted, passive continuous glucose monitor. It integrates an amperometric glucose sensor interface, a near field communication (NFC) wireless front-end and a fully digital switched mode power management unit for supply regulation and on board battery charging. It uses 13.56 MHz (ISM) band to harvest energy and backscatter data to an NFC reader. System was implemented in 14nm ...

  9. Fully simulatable quantum-secure coin-flipping and applications

    DEFF Research Database (Denmark)

    Lunemann, Carolin; Nielsen, Jesper Buus

    2011-01-01

    schemes which we show how to construct in the given setting. We then show that the interactive generation of random coins at the beginning or during outer protocols allows for quantum-secure realizations of classical schemes, again without any set-up assumptions. As example applications we discuss quantum...... zero-knowledge proofs of knowledge and quantum-secure two-party function evaluation. Both applications assume only fully simulatable coin-flipping and mixed commitments. Since our framework allows to construct fully simulatable coin-flipping from mixed commitments, this in particular shows that mixed...

  10. Design Study of Fully Superconducting Wind Turbine Generators

    DEFF Research Database (Denmark)

    Song, Xiaowei (Andy); Mijatovic, Nenad; Jensen, Bogi Bech

    2015-01-01

    In this paper, two fully superconducting generators employing MgB2 armature winding, with YBCO and MgB2 field winding respectively, are presented and analyzed. The ac loss in armature winding is estimated, and a simple comparative study is carried out. The results show that both electromagnetic...... designs for fully superconducting generators are promising with respect to the power density. However, the cost of removing ac loss in armature winding is as high as $900 000. It is also noted that with the current price of YBCO tape, the generator employing MgB 2 field winding would have lower cost....

  11. A new memory effect (MSD) in fully depleted SOI MOSFETs

    Science.gov (United States)

    Bawedin, M.; Cristoloveanu, S.; Yun, J. G.; Flandre, D.

    2005-09-01

    We demonstrate that the transconductance and drain current of fully depleted MOSFETs can display an interesting time-dependent hysteresis. This new memory effect, called meta-stable dip (MSD), is mainly due to the long carrier generation lifetime in the silicon film. Our parametric analysis shows that the memory window can be adjusted in view of practical applications. Various measurement conditions and devices with different doping, front oxide and silicon film thicknesses are systematically explored. The MSD effect can be generalized to several fully depleted CMOS technologies. The MSD mechanism is discussed and validated by two-dimensional simulations results.

  12. A Fully Implantable, NFC Enabled, Continuous Interstitial Glucose Monitor.

    Science.gov (United States)

    Anabtawi, Nijad; Freeman, Sabrina; Ferzli, Rony

    2016-02-01

    This work presents an integrated system-on-chip (SoC) that forms the core of a long-term, fully implantable, battery assisted, passive continuous glucose monitor. It integrates an amperometric glucose sensor interface, a near field communication (NFC) wireless front-end and a fully digital switched mode power management unit for supply regulation and on board battery charging. It uses 13.56 MHz (ISM) band to harvest energy and backscatter data to an NFC reader. System was implemented in 14nm CMOS technology and validated with post layout simulations.

  13. Lipid Based Formulations of Biopharmaceutics Classification System (BCS Class II Drugs: Strategy, Formulations, Methods and Saturation

    Directory of Open Access Journals (Sweden)

    Šoltýsová I.

    2016-12-01

    Full Text Available Active ingredients in pharmaceuticals differ by their physico-chemical properties and their bioavailability therefore varies. The most frequently used and most convenient way of administration of medicines is oral, however many drugs are little soluble in water. Thus they are not sufficiently effective and suitable for such administration. For this reason a system of lipid based formulations (LBF was developed. Series of formulations were prepared and tested in water and biorelevant media. On the basis of selection criteria, there were selected formulations with the best emulsification potential, good dispersion in the environment and physical stability. Samples of structurally different drugs included in the Class II of the Biopharmaceutics classification system (BCS were obtained, namely Griseofulvin, Glibenclamide, Carbamazepine, Haloperidol, Itraconazol, Triclosan, Praziquantel and Rifaximin, for testing of maximal saturation in formulations prepared from commercially available excipients. Methods were developed for preparation of formulations, observation of emulsification and its description, determination of maximum solubility of drug samples in the respective formulation and subsequent analysis. Saturation of formulations with drugs showed that formulations 80 % XA and 20 % Xh, 35 % XF and 65 % Xh were best able to dissolve the drugs which supports the hypothesis that it is desirable to identify limited series of formulations which could be generally applied for this purpose.

  14. High-Level Waste Glass Formulation Model Sensitivity Study 2009 Glass Formulation Model Versus 1996 Glass Formulation Model

    International Nuclear Information System (INIS)

    Belsher, J.D.; Meinert, F.L.

    2009-01-01

    This document presents the differences between two HLW glass formulation models (GFM): The 1996 GFM and 2009 GFM. A glass formulation model is a collection of glass property correlations and associated limits, as well as model validity and solubility constraints; it uses the pretreated HLW feed composition to predict the amount and composition of glass forming additives necessary to produce acceptable HLW glass. The 2009 GFM presented in this report was constructed as a nonlinear optimization calculation based on updated glass property data and solubility limits described in PNNL-18501 (2009). Key mission drivers such as the total mass of HLW glass and waste oxide loading are compared between the two glass formulation models. In addition, a sensitivity study was performed within the 2009 GFM to determine the effect of relaxing various constraints on the predicted mass of the HLW glass.

  15. Formulation of Sustained-Release Diltiazem Matrix Tablets Using ...

    African Journals Online (AJOL)

    Erah

    surface, their drug release behavior appears simple, but ... matrix material for the formulation of ..... formulation F5 (,) and reference formulations. ( , □). 0. 50. 100. 150. 200. 250. 300. 0. 3. 6 .... Coviello T, Matricardi P, Marianecci C, Alhaique F.

  16. Constraining the surface properties of effective Skyrme interactions

    Science.gov (United States)

    Jodon, R.; Bender, M.; Bennaceur, K.; Meyer, J.

    2016-08-01

    Background: Deformation energy surfaces map how the total binding energy of a nuclear system depends on the geometrical properties of intrinsic configurations, thereby providing a powerful tool to interpret nuclear spectroscopy and large-amplitude collective-motion phenomena such as fission. The global behavior of the deformation energy is known to be directly connected to the surface properties of the effective interaction used for its calculation. Purpose: The precise control of surface properties during the parameter adjustment of an effective interaction is key to obtain a reliable and predictive description of nuclear properties. The most relevant indicator is the surface-energy coefficient asurf. There are several possibilities for its definition and estimation, which are not fully equivalent and require a computational effort that can differ by orders of magnitude. The purpose of this study is threefold: first, to identify a scheme for the determination of asurf that offers the best compromise between robustness, precision, and numerical efficiency; second, to analyze the correlation between values for asurf and the characteristic energies of the fission barrier of 240Pu; and third, to lay out an efficient and robust procedure for how the deformation properties of the Skyrme energy density functional (EDF) can be constrained during the parameter fit. Methods: There are several frequently used possibilities to define and calculate the surface energy coefficient asurf of effective interactions built for the purpose of self-consistent mean-field calculations. The most direct access is provided by the model system of semi-infinite nuclear matter, but asurf can also be extracted from the systematics of binding energies of finite nuclei. Calculations can be carried out either self-consistently [Hartree-Fock (HF)], which incorporates quantal shell effects, or in one of the semiclassical extended Thomas-Fermi (ETF) or modified Thomas-Fermi (MTF) approximations. The

  17. [18F]FMeNER-D2: Reliable fully-automated synthesis for visualization of the norepinephrine transporter

    International Nuclear Information System (INIS)

    Rami-Mark, Christina; Zhang, Ming-Rong; Mitterhauser, Markus; Lanzenberger, Rupert; Hacker, Marcus; Wadsak, Wolfgang

    2013-01-01

    Purpose: In neurodegenerative diseases and neuropsychiatric disorders dysregulation of the norepinephrine transporter (NET) has been reported. For visualization of NET availability and occupancy in the human brain PET imaging can be used. Therefore, selective NET-PET tracers with high affinity are required. Amongst these, [ 18 F]FMeNER-D2 is showing the best results so far. Furthermore, a reliable fully automated radiosynthesis is a prerequisite for successful application of PET-tracers. The aim of this work was the automation of [ 18 F]FMeNER-D2 radiolabelling for subsequent clinical use. The presented study comprises 25 automated large-scale syntheses, which were directly applied to healthy volunteers and adult patients suffering from attention deficit hyperactivity disorder (ADHD). Procedures: Synthesis of [ 18 F]FMeNER-D2 was automated within a Nuclear Interface Module. Starting from 20–30 GBq [ 18 F]fluoride, azeotropic drying, reaction with Br 2 CD 2 , distillation of 1-bromo-2-[ 18 F]fluoromethane-D2 ([ 18 F]BFM) and reaction of the pure [ 18 F]BFM with unprotected precursor NER were optimized and completely automated. HPLC purification and SPE procedure were completed, formulation and sterile filtration were achieved on-line and full quality control was performed. Results: Purified product was obtained in a fully automated synthesis in clinical scale allowing maximum radiation safety and routine production under GMP-like manner. So far, more than 25 fully automated syntheses were successfully performed, yielding 1.0–2.5 GBq of formulated [ 18 F]FMeNER-D2 with specific activities between 430 and 1707 GBq/μmol within 95 min total preparation time. Conclusions: A first fully automated [ 18 F]FMeNER-D2 synthesis was established, allowing routine production of this NET-PET tracer under maximum radiation safety and standardization

  18. [{sup 18}F]FMeNER-D2: Reliable fully-automated synthesis for visualization of the norepinephrine transporter

    Energy Technology Data Exchange (ETDEWEB)

    Rami-Mark, Christina [Radiochemistry and Biomarker Development Unit, Division of Nuclear Medicine, Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna (Austria); Department of Inorganic Chemistry, University of Vienna (Austria); Zhang, Ming-Rong [Molecular Imaging Center, National Institute of Radiological Sciences, Chiba (Japan); Mitterhauser, Markus [Radiochemistry and Biomarker Development Unit, Division of Nuclear Medicine, Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna (Austria); Hospital Pharmacy of the General Hospital of Vienna (Austria); Lanzenberger, Rupert [Department of Psychiatry and Psychotherapy, Medical University of Vienna (Austria); Hacker, Marcus [Radiochemistry and Biomarker Development Unit, Division of Nuclear Medicine, Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna (Austria); Wadsak, Wolfgang [Radiochemistry and Biomarker Development Unit, Division of Nuclear Medicine, Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna (Austria); Department of Inorganic Chemistry, University of Vienna (Austria)

    2013-11-15

    Purpose: In neurodegenerative diseases and neuropsychiatric disorders dysregulation of the norepinephrine transporter (NET) has been reported. For visualization of NET availability and occupancy in the human brain PET imaging can be used. Therefore, selective NET-PET tracers with high affinity are required. Amongst these, [{sup 18}F]FMeNER-D2 is showing the best results so far. Furthermore, a reliable fully automated radiosynthesis is a prerequisite for successful application of PET-tracers. The aim of this work was the automation of [{sup 18}F]FMeNER-D2 radiolabelling for subsequent clinical use. The presented study comprises 25 automated large-scale syntheses, which were directly applied to healthy volunteers and adult patients suffering from attention deficit hyperactivity disorder (ADHD). Procedures: Synthesis of [{sup 18}F]FMeNER-D2 was automated within a Nuclear Interface Module. Starting from 20–30 GBq [{sup 18}F]fluoride, azeotropic drying, reaction with Br{sub 2}CD{sub 2}, distillation of 1-bromo-2-[{sup 18}F]fluoromethane-D2 ([{sup 18}F]BFM) and reaction of the pure [{sup 18}F]BFM with unprotected precursor NER were optimized and completely automated. HPLC purification and SPE procedure were completed, formulation and sterile filtration were achieved on-line and full quality control was performed. Results: Purified product was obtained in a fully automated synthesis in clinical scale allowing maximum radiation safety and routine production under GMP-like manner. So far, more than 25 fully automated syntheses were successfully performed, yielding 1.0–2.5 GBq of formulated [{sup 18}F]FMeNER-D2 with specific activities between 430 and 1707 GBq/μmol within 95 min total preparation time. Conclusions: A first fully automated [{sup 18}F]FMeNER-D2 synthesis was established, allowing routine production of this NET-PET tracer under maximum radiation safety and standardization.

  19. [18F]FMeNER-D2: reliable fully-automated synthesis for visualization of the norepinephrine transporter.

    Science.gov (United States)

    Rami-Mark, Christina; Zhang, Ming-Rong; Mitterhauser, Markus; Lanzenberger, Rupert; Hacker, Marcus; Wadsak, Wolfgang

    2013-11-01

    In neurodegenerative diseases and neuropsychiatric disorders dysregulation of the norepinephrine transporter (NET) has been reported. For visualization of NET availability and occupancy in the human brain PET imaging can be used. Therefore, selective NET-PET tracers with high affinity are required. Amongst these, [(18)F]FMeNER-D2 is showing the best results so far. Furthermore, a reliable fully automated radiosynthesis is a prerequisite for successful application of PET-tracers. The aim of this work was the automation of [(18)F]FMeNER-D2 radiolabelling for subsequent clinical use. The presented study comprises 25 automated large-scale syntheses, which were directly applied to healthy volunteers and adult patients suffering from attention deficit hyperactivity disorder (ADHD). Synthesis of [(18)F]FMeNER-D2 was automated within a Nuclear Interface Module. Starting from 20-30 GBq [(18)F]fluoride, azeotropic drying, reaction with Br2CD2, distillation of 1-bromo-2-[(18)F]fluoromethane-D2 ([(18)F]BFM) and reaction of the pure [(18)F]BFM with unprotected precursor NER were optimized and completely automated. HPLC purification and SPE procedure were completed, formulation and sterile filtration were achieved on-line and full quality control was performed. Purified product was obtained in a fully automated synthesis in clinical scale allowing maximum radiation safety and routine production under GMP-like manner. So far, more than 25 fully automated syntheses were successfully performed, yielding 1.0-2.5 GBq of formulated [(18)F]FMeNER-D2 with specific activities between 430 and 1707 GBq/μmol within 95 min total preparation time. A first fully automated [(18)F]FMeNER-D2 synthesis was established, allowing routine production of this NET-PET tracer under maximum radiation safety and standardization. © 2013.

  20. In vitro transcription of a torsionally constrained template

    DEFF Research Database (Denmark)

    Bentin, Thomas; Nielsen, Peter E

    2002-01-01

    RNA polymerase (RNAP) and the DNA template must rotate relative to each other during transcription elongation. In the cell, however, the components of the transcription apparatus may be subject to rotary constraints. For instance, the DNA is divided into topological domains that are delineated...... of torsionally constrained DNA by free RNAP. We asked whether or not a newly synthesized RNA chain would limit transcription elongation. For this purpose we developed a method to immobilize covalently closed circular DNA to streptavidin-coated beads via a peptide nucleic acid (PNA)-biotin conjugate in principle...... constrained. We conclude that transcription of a natural bacterial gene may proceed with high efficiency despite the fact that newly synthesized RNA is entangled around the template in the narrow confines of torsionally constrained supercoiled DNA....

  1. Formulation of lubricating grease using Beeswax thickener

    Science.gov (United States)

    Suhaila, N.; Japar, A.; Aizudin, M.; Aziz, A.; Najib Razali, Mohd

    2018-04-01

    The issues on environmental pollution has brought the industries to seek the alternative green solutions for lubricating grease formulation. The significant challenges in producing modified grease are in which considering the chosen thickener as one of the environmental friendly material. The main purposes of the current research were to formulate lubricant grease using different types of base oils and to study the effect of thickener on the formulated lubricant grease. Used oil and motor oil were used as the base oils for the grease preparation. Beeswax and Damar were used as thickener and additive. The grease is tested based on its consistency, stability and oil bleeding. The prepared greases achieved grease consistency of grade 2 and 3 except for grease with unfiltered used oil. Grease formulated with used oil and synthetic oil tend to harden and loss its lubricating ability under high temperature compared to motor oil’ grease. Grease modification using environmental friendly thickener were successfully formulated but it is considered as a low temperature grease as the beeswax have low melting point of 62°C-65°C.

  2. Bioequivalence assessment of two formulations of ibuprofen

    KAUST Repository

    Al-Talla, Zeyad

    2011-10-19

    Background: This study assessed the relative bioavailability of two formulations of ibuprofen. The first formulation was Doloraz , produced by Al-Razi Pharmaceutical Company, Amman, Jordan. The second forumulation was Brufen , manufactured by Boots Company, Nottingham, UK. Methods and results: A prestudy validation of ibuprofen demonstrated long-term stability, freeze-thaw stability, precision, and accuracy. Twenty-four healthy volunteers were enrolled in this study. After overnight fasting, the two formulations (test and reference) of ibuprofen (100 mg ibuprofen/5 mL suspension) were administered as a single dose on two treatment days separated by a one-week washout period. After dosing, serial blood samples were drawn for a period of 14 hours. Serum harvested from the blood samples was analyzed for the presence of ibuprofen by high-pressure liquid chromatography with ultraviolet detection. Pharmacokinetic parameters were determined from serum concentrations for both formulations. The 90% confidence intervals of the ln-transformed test/reference treatment ratios for peak plasma concentration and area under the concentration-time curve (AUC) parameters were found to be within the predetermined acceptable interval of 80%-125% set by the US Food and Drug Administration. Conclusion: Analysis of variance for peak plasma concentrations and AUC parameters showed no significant difference between the two formulations and, therefore, Doloraz was considered bioequivalent to Brufen. 2011 Al-Talla et al, publisher and licensee Dove Medical Press Ltd.

  3. Node Discovery and Interpretation in Unstructured Resource-Constrained Environments

    DEFF Research Database (Denmark)

    Gechev, Miroslav; Kasabova, Slavyana; Mihovska, Albena D.

    2014-01-01

    for the discovery, linking and interpretation of nodes in unstructured and resource-constrained network environments and their interrelated and collective use for the delivery of smart services. The model is based on a basic mathematical approach, which describes and predicts the success of human interactions...... in the context of long-term relationships and identifies several key variables in the context of communications in resource-constrained environments. The general theoretical model is described and several algorithms are proposed as part of the node discovery, identification, and linking processes in relation...

  4. Value, Cost, and Sharing: Open Issues in Constrained Clustering

    Science.gov (United States)

    Wagstaff, Kiri L.

    2006-01-01

    Clustering is an important tool for data mining, since it can identify major patterns or trends without any supervision (labeled data). Over the past five years, semi-supervised (constrained) clustering methods have become very popular. These methods began with incorporating pairwise constraints and have developed into more general methods that can learn appropriate distance metrics. However, several important open questions have arisen about which constraints are most useful, how they can be actively acquired, and when and how they should be propagated to neighboring points. This position paper describes these open questions and suggests future directions for constrained clustering research.

  5. Development of a fully injectable calcium phosphate cement

    Indian Academy of Sciences (India)

    Permanent link: https://www.ias.ac.in/article/fulltext/boms/026/04/0415-0422. Keywords. Calcium phosphate cements; hydroxyapatite; bioceramics; bone substitute; orthopedic; dental. Abstract. A study on the development of a fully injectable calcium phosphate cement for orthopedic and dental applications is presented.

  6. 7 CFR 635.4 - Failure to fully comply.

    Science.gov (United States)

    2010-01-01

    ... to participants who are determined by the Chief to have made a good faith effort to comply fully with... whether a participant acted in good faith and rendered substantial performance under paragraph (b) of this..., the Chief, or designee, may grant relief in accordance with § 635.5 if the participant made a good...

  7. Peirce and Rationalism: Is Peirce a Fully Semiotic Philosopher?

    Science.gov (United States)

    Stables, Andrew

    2014-01-01

    While Peirce is a seminal figure for contemporary semiotic philosophers, it is axiomatic of a fully semiotic perspective that no philosopher or philosophy (semiotics included) can provide any final answer, as signs are always interpreted and the context of interpretation always varies. Semiosis is evolutionary: it may or may not be construed as…

  8. SYSTEMATIZATION AND ANALYSIS OF PARTIALLY AND FULLY HOMOMORPHIC CRYPTOSYSTEM

    Directory of Open Access Journals (Sweden)

    A. V. Epishkina

    2016-12-01

    Full Text Available In this article provides an overview of the known partially and fully homomorphic cryptosystem, such as: RSA, ElGamal, Paillier, Gentry and Halevi. Justified the homomorphic properties of the considered cryptosystems. The comparative analysis of the homomorphic encryption algorithms has been committed

  9. Viscosity solutions of fully nonlinear functional parabolic PDE

    Directory of Open Access Journals (Sweden)

    Liu Wei-an

    2005-01-01

    Full Text Available By the technique of coupled solutions, the notion of viscosity solutions is extended to fully nonlinear retarded parabolic equations. Such equations involve many models arising from optimal control theory, economy and finance, biology, and so forth. The comparison principle is shown. Then the existence and uniqueness are established by the fixed point theory.

  10. A Fully Inkjet Printed 3D Honeycomb Inspired Patch Antenna

    KAUST Repository

    McKerricher, Garret; Titterington, Don; Shamim, Atif

    2015-01-01

    by inkjet printing in this work. This is the first demonstration of a fully 3D Multijet printing process with integrated polymer and metal. A 2.4 GHz patch antenna is successfully fabricated with good performance proving the viability of the process

  11. Design of a Fully-Passive Transfemoral Prosthesis Prototype

    NARCIS (Netherlands)

    Behrens, Sebastiaan Maria; Behrens, S.M.; Ünal, Ramazan; Unal, R.; Hekman, Edsko E.G.; Carloni, Raffaella; Stramigioli, Stefano; Koopman, Hubertus F.J.M.

    In this study, we present the mechanical design of a prototype of a fully-passive transfemoral prosthesis for normal walking. The conceptual working principle at the basis of the design is inspired by the power flow in human gait, with the main purpose of realizing an energy efficient device. The

  12. Benchmarking of regenerative braking for a fully electric car

    NARCIS (Netherlands)

    Varocky, B.J.; Nijmeijer, H.; Jansen, S.; Besselink, I.J.M.; Mansvelder, R.; Mansvelders, R.E.

    2011-01-01

    Short range of electric vehicles is one of the stumbling blocks in the way of electric cars to gaining wide user acceptance and becoming a major market player. The possibility to recover vehicle energy otherwise lost as heat during braking is an inherent advantage of a hybrid electric or a fully

  13. A Fully Transparent Resistive Memory for Harsh Environments

    KAUST Repository

    Yang, Po-Kang; Ho, Chih-Hsiang; Lien, Der-Hsien; Duran Retamal, Jose Ramon; Kang, Chen-Fang; Chen, Kuan-Ming; Huang, Teng-Han; Yu, Yueh-Chung; Wu, Chih-I; He, Jr-Hau

    2015-01-01

    A fully transparent resistive memory (TRRAM) based on Hafnium oxide (HfO2) with excellent transparency, resistive switching capability, and environmental stability is demonstrated. The retention time measured at 85 °C is over 3 × 104 sec

  14. Fully probabilistic design: the way for optimizing of concrete structures

    Directory of Open Access Journals (Sweden)

    I. Laníková

    Full Text Available Some standards for the design of concrete structures (e.g. EC2 and the original ČSN 73 1201-86 allow a structure to be designed by several methods. This contribution documents the fact that even if a structure does not comply with the partial reliability factor method, according to EC2, it can satisfy the conditions during the application of the fully probabilistic approach when using the same standard. From an example of the reliability of a prestressed spun concrete pole designed by the partial factor method and fully probabilistic approach according to the Eurocode it is evident that an expert should apply a more precise (though unfortunately more complicated method in the limiting cases. The Monte Carlo method, modified by the Latin Hypercube Sampling (LHS method, has been used for the calculation of reliability. Ultimate and serviceability limit states were checked for the partial factor method and fully probabilistic design. As a result of fully probabilistic design it is possible to obtain a more efficient design for a structure.

  15. LV challenge LKEB contribution : fully automated myocardial contour detection

    NARCIS (Netherlands)

    Wijnhout, J.S.; Hendriksen, D.; Assen, van H.C.; Geest, van der R.J.

    2009-01-01

    In this paper a contour detection method is described and evaluated on the evaluation data sets of the Cardiac MR Left Ventricle Segmentation Challenge as part of MICCAI 2009s 3D Segmentation Challenge for Clinical Applications. The proposed method, using 2D AAM and 3D ASM, performs a fully

  16. A fully integrated 16 channel digitally trimmed pulse shaping amplifier

    International Nuclear Information System (INIS)

    Hearn, W.E.; Wright, M.E.

    1993-11-01

    A fully integrated CMOS pulse shaping amplifier has been developed at LBL. All frequency dependent networks are included on the chip. Provision is made for tuning to compensate for process variations. The overall architecture and details of the circuitry are discussed. Test results are presented

  17. New approach to solve symmetric fully fuzzy linear systems

    Indian Academy of Sciences (India)

    In this paper, we present a method to solve fully fuzzy linear systems with symmetric coefficient matrix. The symmetric coefficient matrix is decomposed into two systems of equations by using Cholesky method and then a solution can be obtained. Numerical examples are given to illustrate our method.

  18. Cyclodextrins as excipients in tablet formulations.

    Science.gov (United States)

    Conceição, Jaime; Adeoye, Oluwatomide; Cabral-Marques, Helena Maria; Lobo, José Manuel Sousa

    2018-04-22

    This paper aims to provide a critical review of cyclodextrins as excipients in tablet formulations, highlighting: (i) the principal pharmaceutical applications of cyclodextrins; (ii) the most relevant technological aspects in pharmaceutical formulation development; and (iii) the actual regulatory status of cyclodextrins. Moreover, several illustrative examples are presented. Cyclodextrins can be used as complexing excipients in tablet formulations for low-dose drugs. By contrast, for medium-dose drugs and/or when the complexation efficiency is low, the methods to enhance the complexation efficiency play a key part in reducing the cyclodextrin quantity. In addition, these compounds are used as fillers, disintegrants, binders and multifunctional direct compression excipients of the tablets. Copyright © 2018 Elsevier Ltd. All rights reserved.

  19. STRATEGY FORMULATION PROCESS AND INNOVATION PERFORMANCE NEXUS

    Directory of Open Access Journals (Sweden)

    Chijioke Nwachukwu

    2018-03-01

    Full Text Available The purpose of this study is to examine the link between strategy formulation process and innovation performance indicators in microfinance banks in Nigeria (MFBs. 100 employees of leading microfinance banks were randomly selected for this study. 80 questionnaires were returned but only 76 were found usable for the analysis. Regression analysis technique was used in examining the nature of the relationships of the variables and for hypotheses testing. The authors used exploratory factor analysis and Cronbach's alpha to test for the validity and reliability of the questionnaires. The results show that strategy formulation process has a positive effect on process innovation performance, product innovation performance and marketing innovation performance. Thus, all the three hypotheses tested were supported. The authors, therefore, concludes that a systematic strategy formulation process is necessary for firms to achieve and sustain process innovation performance, product innovation performance and marketing innovation performance. This study proposed suggestion for further studies.

  20. Water channel experiments of a novel fully-passive flapping-foil turbine

    Science.gov (United States)

    Boudreau, Matthieu; Dumas, Guy; Rahimpour, Mostafa; Oshkai, Peter

    2016-11-01

    Experiments have been conducted to assess the performances of a fully-passive flapping-foil hydrokinetic turbine for which the blade's motions are stemming from the interaction between the blade's elastic supports (springs and dampers) and the flow field. Previous numerical studies conducted by Peng & Zhu (2009) and Zhu (2012) have proved that a simplified version of such a turbine can extract a substantial amount of energy from the flow while offering the potential to greatly simplify the complex mechanical apparatus needed to constrain and link the blade's pitching and heaving motions in the case of the more classical flapping-foil turbine (e.g., Kinsey et al., 2011). Based on the promising numerical investigations of Veilleux (2014) and Veilleux & Dumas (2016), who proposed a more general version of this novel concept, a prototype has been built and tested in a water channel at a chord Reynolds number of 17,000. Periodic motions of large amplitudes have been observed leading to interesting energy harvesting efficiencies reaching 25% for some specific sets of structural parameters. The sensitivity of the turbine's dynamics to each of the seven structural parameters appearing in the equations of motion has been experimentally evaluated around a case close to the optimal one. Financial support from the Natural Sciences and Engineering Research Council of Canada (NSERC) is gratefully acknowledged by the authors.

  1. RAACFDb: Rheumatoid arthritis ayurvedic classical formulations database.

    Science.gov (United States)

    Mohamed Thoufic Ali, A M; Agrawal, Aakash; Sajitha Lulu, S; Mohana Priya, A; Vino, S

    2017-02-02

    In the past years, the treatment of rheumatoid arthritis (RA) has undergone remarkable changes in all therapeutic modes. The present newfangled care in clinical research is to determine and to pick a new track for better treatment options for RA. Recent ethnopharmacological investigations revealed that traditional herbal remedies are the most preferred modality of complementary and alternative medicine (CAM). However, several ayurvedic modes of treatments and formulations for RA are not much studied and documented from Indian traditional system of medicine. Therefore, this directed us to develop an integrated database, RAACFDb (acronym: Rheumatoid Arthritis Ayurvedic Classical Formulations Database) by consolidating data from the repository of Vedic Samhita - The Ayurveda to retrieve the available formulations information easily. Literature data was gathered using several search engines and from ayurvedic practitioners for loading information in the database. In order to represent the collected information about classical ayurvedic formulations, an integrated database is constructed and implemented on a MySQL and PHP back-end. The database is supported by describing all the ayurvedic classical formulations for the treatment rheumatoid arthritis. It includes composition, usage, plant parts used, active ingredients present in the composition and their structures. The prime objective is to locate ayurvedic formulations proven to be quite successful and highly effective among the patients with reduced side effects. The database (freely available at www.beta.vit.ac.in/raacfdb/index.html) hopefully enables easy access for clinical researchers and students to discover novel leads with reduced side effects. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  2. Formulation and stability testing of photolabile drugs.

    Science.gov (United States)

    Tønnesen, H H

    2001-08-28

    Exposure of a drug to irradiation can influence the stability of the formulation, leading to changes in the physicochemical properties of the product. The influence of excipients of frequently used stabilizers is often difficult to predict and, therefore, stability testing of the final preparation is important. The selection of a protective packaging must be based on knowledge about the wavelength causing the instability. Details on drug photoreactivity will also be helpful in order to minimize side-effects and/or optimize drug targeting by developing photoresponsive drug delivery systems. This review focuses on practical problems related to formulation and stability testing of photolabile drugs.

  3. Controlled-release tablet formulation of isoniazid.

    Science.gov (United States)

    Jain, N K; Kulkarni, K; Talwar, N

    1992-04-01

    Guar (GG) and Karaya gums (KG) alone and in combination with hydroxy-propylmethylcellulose (HPMC) were evaluated as release retarding materials to formulate a controlled-release tablet dosage form of isoniazid (1). In vitro release of 1 from tablets followed non-Fickian release profile with rapid initial release. Urinary excretion studies in normal subjects showed steady-state levels of 1 for 13 h. In vitro and in vivo data correlated (r = 0.9794). The studies suggested the potentiality of GG and KG as release retarding materials in formulating controlled-release tablet dosage forms of 1.

  4. An exact approach for aggregated formulations

    DEFF Research Database (Denmark)

    Gamst, Mette; Spoorendonk, Simon

    Aggregating formulations is a powerful approach for transforming problems into taking more tractable forms. Aggregated formulations can, though, have drawbacks: some information may get lost in the aggregation and { put in a branch-and-bound context { branching may become very di_cult and even....... The paper includes general considerations on types of problems for which the method is of particular interest. Furthermore, we prove the correctness of the procedure and consider how to include extensions such as cutting planes and advanced branching strategies....

  5. Quaternionic formulation of the exact parity model

    Energy Technology Data Exchange (ETDEWEB)

    Brumby, S.P.; Foot, R.; Volkas, R.R.

    1996-02-28

    The exact parity model (EPM) is a simple extension of the standard model which reinstates parity invariance as an unbroken symmetry of nature. The mirror matter sector of the model can interact with ordinary matter through gauge boson mixing, Higgs boson mixing and, if neutrinos are massive, through neutrino mixing. The last effect has experimental support through the observed solar and atmospheric neutrino anomalies. In the paper it is shown that the exact parity model can be formulated in a quaternionic framework. This suggests that the idea of mirror matter and exact parity may have profound implications for the mathematical formulation of quantum theory. 13 refs.

  6. Quaternionic formulation of the exact parity model

    International Nuclear Information System (INIS)

    Brumby, S.P.; Foot, R.; Volkas, R.R.

    1996-01-01

    The exact parity model (EPM) is a simple extension of the standard model which reinstates parity invariance as an unbroken symmetry of nature. The mirror matter sector of the model can interact with ordinary matter through gauge boson mixing, Higgs boson mixing and, if neutrinos are massive, through neutrino mixing. The last effect has experimental support through the observed solar and atmospheric neutrino anomalies. In the paper it is shown that the exact parity model can be formulated in a quaternionic framework. This suggests that the idea of mirror matter and exact parity may have profound implications for the mathematical formulation of quantum theory. 13 refs

  7. Coherent Structures and Entropy in Constrained, Modulationally Unstable, Nonintegrable Systems

    International Nuclear Information System (INIS)

    Rumpf, Benno; Newell, Alan C.

    2001-01-01

    Many studies have shown that nonintegrable systems with modulational instabilities constrained by more than one conservation law exhibit universal long time behavior involving large coherent structures in a sea of small fluctuations. We show how this behavior can be explained in detail by simple thermodynamic arguments

  8. Invariant set computation for constrained uncertain discrete-time systems

    NARCIS (Netherlands)

    Athanasopoulos, N.; Bitsoris, G.

    2010-01-01

    In this article a novel approach to the determination of polytopic invariant sets for constrained discrete-time linear uncertain systems is presented. First, the problem of stabilizing a prespecified initial condition set in the presence of input and state constraints is addressed. Second, the

  9. Applications of a Constrained Mechanics Methodology in Economics

    Science.gov (United States)

    Janova, Jitka

    2011-01-01

    This paper presents instructive interdisciplinary applications of constrained mechanics calculus in economics on a level appropriate for undergraduate physics education. The aim of the paper is (i) to meet the demand for illustrative examples suitable for presenting the background of the highly expanding research field of econophysics even at the…

  10. Constraining the evolution of the Hubble Parameter using cosmic chronometers

    Science.gov (United States)

    Dickinson, Hugh

    2017-08-01

    Substantial investment is being made in space- and ground-based missions with the goal of revealing the nature of the observed cosmic acceleration. This is one of the most important unsolved problems in cosmology today.We propose here to constrain the evolution of the Hubble parameter [H(z)] between 1.3 fundamental nature of dark energy.

  11. Nonmonotonic Skeptical Consequence Relation in Constrained Default Logic

    Directory of Open Access Journals (Sweden)

    Mihaiela Lupea

    2010-12-01

    Full Text Available This paper presents a study of the nonmonotonic consequence relation which models the skeptical reasoning formalised by constrained default logic. The nonmonotonic skeptical consequence relation is defined using the sequent calculus axiomatic system. We study the formal properties desirable for a good nonmonotonic relation: supraclassicality, cut, cautious monotony, cumulativity, absorption, distribution. 

  12. Extended shadow test approach for constrained adaptive testing

    NARCIS (Netherlands)

    Veldkamp, Bernard P.; Ariel, A.

    2002-01-01

    Several methods have been developed for use on constrained adaptive testing. Item pool partitioning, multistage testing, and testlet-based adaptive testing are methods that perform well for specific cases of adaptive testing. The weighted deviation model and the Shadow Test approach can be more

  13. Time-constrained project scheduling with adjacent resources

    NARCIS (Netherlands)

    Hurink, Johann L.; Kok, A.L.; Paulus, J.J.; Schutten, Johannes M.J.

    We develop a decomposition method for the Time-Constrained Project Scheduling Problem (TCPSP) with adjacent resources. For adjacent resources the resource units are ordered and the units assigned to a job have to be adjacent. On top of that, adjacent resources are not required by single jobs, but by

  14. Evaluation of constrained mobility for programmability in network management

    NARCIS (Netherlands)

    Bohoris, C.; Liotta, A.; Pavlou, G.; Ambler, A.P.; Calo, S.B.; Kar, G.

    2000-01-01

    In recent years, a significant amount of research work has addressed the use of code mobility in network management. In this paper, we introduce first three aspects of code mobility and argue that constrained mobility offers a natural and easy approach to network management programmability. While

  15. Testing a Constrained MPC Controller in a Process Control Laboratory

    Science.gov (United States)

    Ricardez-Sandoval, Luis A.; Blankespoor, Wesley; Budman, Hector M.

    2010-01-01

    This paper describes an experiment performed by the fourth year chemical engineering students in the process control laboratory at the University of Waterloo. The objective of this experiment is to test the capabilities of a constrained Model Predictive Controller (MPC) to control the operation of a Double Pipe Heat Exchanger (DPHE) in real time.…

  16. In vitro transcription of a torsionally constrained template

    DEFF Research Database (Denmark)

    Bentin, Thomas; Nielsen, Peter E

    2002-01-01

    of torsionally constrained DNA by free RNAP. We asked whether or not a newly synthesized RNA chain would limit transcription elongation. For this purpose we developed a method to immobilize covalently closed circular DNA to streptavidin-coated beads via a peptide nucleic acid (PNA)-biotin conjugate in principle...

  17. GPS-based ionospheric tomography with a constrained adaptive ...

    Indian Academy of Sciences (India)

    Gauss weighted function is introduced to constrain the tomography system in the new method. It can resolve the ... the research focus in the fields of space geodesy and ... ment of GNSS such as GPS, Glonass, Galileo and. Compass, as these ...

  18. Constrained variational calculus for higher order classical field theories

    Energy Technology Data Exchange (ETDEWEB)

    Campos, Cedric M; De Leon, Manuel; De Diego, David MartIn, E-mail: cedricmc@icmat.e, E-mail: mdeleon@icmat.e, E-mail: david.martin@icmat.e [Instituto de Ciencias Matematicas, CSIC-UAM-UC3M-UCM, Serrano 123, 28006 Madrid (Spain)

    2010-11-12

    We develop an intrinsic geometrical setting for higher order constrained field theories. As a main tool we use an appropriate generalization of the classical Skinner-Rusk formalism. Some examples of applications are studied, in particular to the geometrical description of optimal control theory for partial differential equations.

  19. Identification of different geologic units using fuzzy constrained resistivity tomography

    Science.gov (United States)

    Singh, Anand; Sharma, S. P.

    2018-01-01

    Different geophysical inversion strategies are utilized as a component of an interpretation process that tries to separate geologic units based on the resistivity distribution. In the present study, we present the results of separating different geologic units using fuzzy constrained resistivity tomography. This was accomplished using fuzzy c means, a clustering procedure to improve the 2D resistivity image and geologic separation within the iterative minimization through inversion. First, we developed a Matlab-based inversion technique to obtain a reliable resistivity image using different geophysical data sets (electrical resistivity and electromagnetic data). Following this, the recovered resistivity model was converted into a fuzzy constrained resistivity model by assigning the highest probability value of each model cell to the cluster utilizing fuzzy c means clustering procedure during the iterative process. The efficacy of the algorithm is demonstrated using three synthetic plane wave electromagnetic data sets and one electrical resistivity field dataset. The presented approach shows improvement on the conventional inversion approach to differentiate between different geologic units if the correct number of geologic units will be identified. Further, fuzzy constrained resistivity tomography was performed to examine the augmentation of uranium mineralization in the Beldih open cast mine as a case study. We also compared geologic units identified by fuzzy constrained resistivity tomography with geologic units interpreted from the borehole information.

  20. Constrained variational calculus for higher order classical field theories

    International Nuclear Information System (INIS)

    Campos, Cedric M; De Leon, Manuel; De Diego, David MartIn

    2010-01-01

    We develop an intrinsic geometrical setting for higher order constrained field theories. As a main tool we use an appropriate generalization of the classical Skinner-Rusk formalism. Some examples of applications are studied, in particular to the geometrical description of optimal control theory for partial differential equations.

  1. Bounds on the capacity of constrained two-dimensional codes

    DEFF Research Database (Denmark)

    Forchhammer, Søren; Justesen, Jørn

    2000-01-01

    Bounds on the capacity of constrained two-dimensional (2-D) codes are presented. The bounds of Calkin and Wilf apply to first-order symmetric constraints. The bounds are generalized in a weaker form to higher order and nonsymmetric constraints. Results are given for constraints specified by run-l...

  2. The balance of payment-constrained economic growth in Ethiopia ...

    African Journals Online (AJOL)

    The objective of this paper is to empirically test the validity of the simplified version of the balance of payment-constrained economic growth model for Ethiopia during the period 1971-20082. According to the model, economies only grow at a pace allowed by the constraints imposed by the requirement of balance of payment ...

  3. Toward cognitively constrained models of language processing : A review

    NARCIS (Netherlands)

    Vogelzang, Margreet; Mills, Anne C.; Reitter, David; van Rij, Jacolien; Hendriks, Petra; van Rijn, Hedderik

    2017-01-01

    Language processing is not an isolated capacity, but is embedded in other aspects of our cognition. However, it is still largely unexplored to what extent and how language processing interacts with general cognitive resources. This question can be investigated with cognitively constrained

  4. The Balance of Payment-Constrained Economic Growth in Ethiopia ...

    African Journals Online (AJOL)

    Administrator

    Page 100 financial liberalization and export promotion strategy necessarily lead to better growth performance. Rather, one should consider not only exports of goods and services, but also the income elasticity of imports. The balance of payments-constrained growth model postulates that the rate of growth in any country is ...

  5. Evaluating potentialities and constrains of Problem Based Learning curriculum

    DEFF Research Database (Denmark)

    Guerra, Aida

    2013-01-01

    This paper presents a research design to evaluate Problem Based Learning (PBL) curriculum potentialities and constrains for future changes. PBL literature lacks examples of how to evaluate and analyse established PBL learning environments to address new challenges posed. The research design......) in the curriculum and a mean to choose cases for further case study (third phase)....

  6. Binary classification posed as a quadratically constrained quadratic ...

    Indian Academy of Sciences (India)

    Binary classification is posed as a quadratically constrained quadratic problem and solved using the proposed method. Each class in the binary classification problem is modeled as a multidimensional ellipsoid to forma quadratic constraint in the problem. Particle swarms help in determining the optimal hyperplane or ...

  7. GPS-based ionospheric tomography with a constrained adaptive ...

    Indian Academy of Sciences (India)

    According to the continuous smoothness of the variations of ionospheric electron density (IED) among neighbouring voxels, Gauss weighted function is introduced to constrain the tomography system in the new method. It can resolve the dependence on the initial values for those voxels without any GPS rays traversing them ...

  8. Time-constrained project scheduling with adjacent resources

    NARCIS (Netherlands)

    Hurink, Johann L.; Kok, A.L.; Paulus, J.J.; Schutten, Johannes M.J.

    2008-01-01

    We develop a decomposition method for the Time-Constrained Project Scheduling Problem (TCPSP) with Adjacent Resources. For adjacent resources the resource units are ordered and the units assigned to a job have to be adjacent. On top of that, adjacent resources are not required by single jobs, but by

  9. Constrained relationship agency as the risk factor for intimate ...

    African Journals Online (AJOL)

    We used structural equation modelling to identify and measure constrained relationship agency (CRA) as a latent variable, and then tested the hypothesis that CRA plays a significant role in the pathway between IPV and transactional sex. After controlling for CRA, receiving more material goods from a sexual partner was ...

  10. Chance-constrained optimization of demand response to price signals

    DEFF Research Database (Denmark)

    Dorini, Gianluca Fabio; Pinson, Pierre; Madsen, Henrik

    2013-01-01

    within a recursive least squares (RLS) framework using data measurable at the grid level, in an adaptive fashion. Optimal price signals are generated by embedding the FIR models within a chance-constrained optimization framework. The objective is to keep the price signal as unchanged as possible from...

  11. Solution of a Complex Least Squares Problem with Constrained Phase.

    Science.gov (United States)

    Bydder, Mark

    2010-12-30

    The least squares solution of a complex linear equation is in general a complex vector with independent real and imaginary parts. In certain applications in magnetic resonance imaging, a solution is desired such that each element has the same phase. A direct method for obtaining the least squares solution to the phase constrained problem is described.

  12. Dark matter, constrained minimal supersymmetric standard model, and lattice QCD.

    Science.gov (United States)

    Giedt, Joel; Thomas, Anthony W; Young, Ross D

    2009-11-13

    Recent lattice measurements have given accurate estimates of the quark condensates in the proton. We use these results to significantly improve the dark matter predictions in benchmark models within the constrained minimal supersymmetric standard model. The predicted spin-independent cross sections are at least an order of magnitude smaller than previously suggested and our results have significant consequences for dark matter searches.

  13. Constrained Quantum Mechanics: Chaos in Non-Planar Billiards

    Science.gov (United States)

    Salazar, R.; Tellez, G.

    2012-01-01

    We illustrate some of the techniques to identify chaos signatures at the quantum level using as guiding examples some systems where a particle is constrained to move on a radial symmetric, but non-planar, surface. In particular, two systems are studied: the case of a cone with an arbitrary contour or "dunce hat billiard" and the rectangular…

  14. Constrained control of a once-through boiler with recirculation

    DEFF Research Database (Denmark)

    Trangbæk, K

    2008-01-01

    There is an increasing need to operate power plants at low load for longer periods of time. When a once-through boiler operates at a sufficiently low load, recirculation is introduced, significantly altering the control structure. This paper illustrates the possibilities for using constrained con...

  15. On the Integrated Job Scheduling and Constrained Network Routing Problem

    DEFF Research Database (Denmark)

    Gamst, Mette

    This paper examines the NP-hard problem of scheduling a number of jobs on a finite set of machines such that the overall profit of executed jobs is maximized. Each job demands a number of resources, which must be sent to the executing machine via constrained paths. Furthermore, two resource demand...

  16. Effective Teaching of Economics: A Constrained Optimization Problem?

    Science.gov (United States)

    Hultberg, Patrik T.; Calonge, David Santandreu

    2017-01-01

    One of the fundamental tenets of economics is that decisions are often the result of optimization problems subject to resource constraints. Consumers optimize utility, subject to constraints imposed by prices and income. As economics faculty, instructors attempt to maximize student learning while being constrained by their own and students'…

  17. Vacuum expectation values in a scalar constrained theory

    International Nuclear Information System (INIS)

    Alonso, F.; Julve, J.; Tiemblo, A.

    1985-01-01

    A class of finite Green functions in the context of a scalar constrained theory is studied. In a particular model the one-point GFs show that the vacuum expectation values for some fields vanish while one of them remains finite, a feature exhibited by the Goldstone and Higgs fields respectively. (orig.)

  18. Lagrangian formalism for constrained systems. 2. Gauge symmetries

    International Nuclear Information System (INIS)

    Pyatov, P.N.

    1990-01-01

    Using the Lagrangian formalism for constrained systems all gauge symmetries peculiar for a given Lagrangian system and in establishing the relation between them and the constraints are constructed. Besides, the question about the possible dependence of gauge transformations on accelerations and other higher order time derivatives of coordinates is clarified. 14 refs

  19. Factors constraining accessibility and usage of information among ...

    African Journals Online (AJOL)

    Various factors may negatively impact on information acquisition and utilisation. To improve understanding of the determinants of information acquisition and utilisation, this study investigated the factors constraining accessibility and usage of poultry management information in three rural districts of Tanzania. The findings ...

  20. Constrained Geocast to Support Cooperative Adaptive Cruise Control (CACC) Merging

    NARCIS (Netherlands)

    Klein Wolterink, W.; Heijenk, Geert; Karagiannis, Georgios

    2010-01-01

    In this paper we introduce a new geocasting concept to target vehicles based on where they will be in the direct future, in stead of their current position. We refer to this concept as constrained geocast. This may be useful in situations where vehicles have interdependencies based on (future)

  1. New waste based clinkers: Belite and lime formulations

    International Nuclear Information System (INIS)

    Raupp-Pereira, Fabiano; Ball, Richard James; Rocha, Joao; Labrincha, Joao A.; Allen, Geoffrey C.

    2008-01-01

    This work describes the formulation of new belite-based (CR2) and lime-based (CR3) cementitious materials derived from industrial wastes, such as sludges (generated in the Al-anodising and surface coating industrial processes, potable water filtration/cleaning operations and in marble sawing processes) and foundry sand. Powder mixtures were prepared and fired at different temperatures. For comparison, similar formulations were prepared with pre-treated and commercially available natural raw materials and processed in similar conditions. The thermal process was followed by differential scanning calorimetry (DSC) and high-temperature powder X-ray diffraction (HT-XRD) studies. The CR2 clinker was found to contain belite as the main cementitious phase, the main polymorph being identified by NMR. The CR3 clinker contained common cementitious phases, such as C 3 A and C 3 S, but free lime and calcium aluminium oxide sulphates were also identified by high temperature XRD and NMR. Then the corresponding cement was prepared and the evolution of the mechanical strength with time was evaluated. The lime-based cement obtained from wastes shows a stronger hardening character than the standard material, which tends to show dusting phenomena due to the presence of a reasonable amount of free lime (as the result of its expansive reaction with ambient moisture). Some fluxing impurities (e.g. alkalis) present in the waste materials improve the overall reactivity of the mixture and induces the combination of the lime in CR3. Raman, XPS and FIB techniques were used to fully characterise the aged cements

  2. Effect of slip on heat transfer and entropy generation characteristics of simplified Phan-Thien–Tanner fluids with viscous dissipation under uniform heat flux boundary conditions: Exponential formulation

    International Nuclear Information System (INIS)

    Anand, Vishal

    2016-01-01

    Highlights: • Exponential formulation of s-PTT model used. • Heat transfer and entropy generation characteristics studied. • Effects of three slip laws examined. • Exponential formulation more accurate than linear formulation. - Abstract: This study concerns the heat transfer and entropy generation characteristics of viscoelastic fluid flow modeled by the exponential formulation of simplified Phan-Thien–Tanner (s-PTT) model. This is the first such study in literature of thermal behavior of viscoelastic fluids modeled by the exponential formulation of s-PTT model. The flow between two parallel plates is laminar, hydrodynamically and thermally fully developed, viscous dissipative and subject to uniform heat flux on the walls. The slip velocity boundary condition is imposed on the fluid–solid interface and the slip is captured by three slip laws, namely, Navier's non-linear slip law, Hatzikiriakos slip law, and asymptotic slip law. The governing equations have been solved analytically. Closed form solutions for the velocity distribution have been derived while the temperature distribution is presented in terms of an infinite but convergent series. The results pertaining to the three slip laws have been presented in detail. Finally, a comparison has been made between the results for exponential formulation and those for the linear formulation of the s-PTT model. The comparison shows that results for linear formulation deviate significantly from those for exponential formulation and thus the accuracy of the exponential formulation justifies the extra mathematical complexity which it entails.

  3. Dynamical insurance models with investment: Constrained singular problems for integrodifferential equations

    Science.gov (United States)

    Belkina, T. A.; Konyukhova, N. B.; Kurochkin, S. V.

    2016-01-01

    Previous and new results are used to compare two mathematical insurance models with identical insurance company strategies in a financial market, namely, when the entire current surplus or its constant fraction is invested in risky assets (stocks), while the rest of the surplus is invested in a risk-free asset (bank account). Model I is the classical Cramér-Lundberg risk model with an exponential claim size distribution. Model II is a modification of the classical risk model (risk process with stochastic premiums) with exponential distributions of claim and premium sizes. For the survival probability of an insurance company over infinite time (as a function of its initial surplus), there arise singular problems for second-order linear integrodifferential equations (IDEs) defined on a semiinfinite interval and having nonintegrable singularities at zero: model I leads to a singular constrained initial value problem for an IDE with a Volterra integral operator, while II model leads to a more complicated nonlocal constrained problem for an IDE with a non-Volterra integral operator. A brief overview of previous results for these two problems depending on several positive parameters is given, and new results are presented. Additional results are concerned with the formulation, analysis, and numerical study of "degenerate" problems for both models, i.e., problems in which some of the IDE parameters vanish; moreover, passages to the limit with respect to the parameters through which we proceed from the original problems to the degenerate ones are singular for small and/or large argument values. Such problems are of mathematical and practical interest in themselves. Along with insurance models without investment, they describe the case of surplus completely invested in risk-free assets, as well as some noninsurance models of surplus dynamics, for example, charity-type models.

  4. Geometrically constrained kinematic global navigation satellite systems positioning: Implementation and performance

    Science.gov (United States)

    Asgari, Jamal; Mohammadloo, Tannaz H.; Amiri-Simkooei, Ali Reza

    2015-09-01

    GNSS kinematic techniques are capable of providing precise coordinates in extremely short observation time-span. These methods usually determine the coordinates of an unknown station with respect to a reference one. To enhance the precision, accuracy, reliability and integrity of the estimated unknown parameters, GNSS kinematic equations are to be augmented by possible constraints. Such constraints could be derived from the geometric relation of the receiver positions in motion. This contribution presents the formulation of the constrained kinematic global navigation satellite systems positioning. Constraints effectively restrict the definition domain of the unknown parameters from the three-dimensional space to a subspace defined by the equation of motion. To test the concept of the constrained kinematic positioning method, the equation of a circle is employed as a constraint. A device capable of moving on a circle was made and the observations from 11 positions on the circle were analyzed. Relative positioning was conducted by considering the center of the circle as the reference station. The equation of the receiver's motion was rewritten in the ECEF coordinates system. A special attention is drawn onto how a constraint is applied to kinematic positioning. Implementing the constraint in the positioning process provides much more precise results compared to the unconstrained case. This has been verified based on the results obtained from the covariance matrix of the estimated parameters and the empirical results using kinematic positioning samples as well. The theoretical standard deviations of the horizontal components are reduced by a factor ranging from 1.24 to 2.64. The improvement on the empirical standard deviation of the horizontal components ranges from 1.08 to 2.2.

  5. Screening of mucoadhesive vaginal gel formulations

    Directory of Open Access Journals (Sweden)

    Ana Ochoa Andrade

    2014-12-01

    Full Text Available Rational design of vaginal drug delivery formulations requires special attention to vehicle properties that optimize vaginal coating and retention. The aim of the present work was to perform a screening of mucoadhesive vaginal gels formulated with carbomer or carrageenan in binary combination with a second polymer (carbomer, guar or xanthan gum. The gels were characterised using in vitroadhesion, spreadability and leakage potential studies, as well as rheological measurements (stress and frequency sweep tests and the effect of dilution with simulated vaginal fluid (SVF on spreadability. Results were analysed using analysis of variance and multiple factor analysis. The combination of polymers enhanced adhesion of both primary gelling agents, carbomer and carrageenan. From the rheological point of view all formulations presented a similar behaviour, prevalently elastic and characterised by loss tangent values well below 1. No correlation between rheological and adhesion behaviour was found. Carbomer and carrageenan gels containing the highest percentage of xanthan gum displayed good in vitro mucoadhesion and spreadability, minimal leakage potential and high resistance to dilution. The positive results obtained with carrageenan-xanthan gum-based gels can encourage the use of natural biocompatible adjuvants in the composition of vaginal products, a formulation field that is currently under the synthetic domain.

  6. Formulation of Sodium Alginate Nanospheres Containing ...

    African Journals Online (AJOL)

    Purpose: The aim of this work was to formulate sodium alginate nanospheres of amphotericin B by controlled gellification method and to evaluate the role of the nanospheres as a “passive carrier” in targeted antifungal therapy. Methods: Sodium alginate nanospheres of amphotericin B were prepared by controlled ...

  7. [Optimization of formulations for dietetic pastry products].

    Science.gov (United States)

    Villarroel, M; Uquiche, E; Brito, G; Cancino, M

    2000-03-01

    Optimized formulations of dietetic pastry products such as cake and sponge cake premixes were formulated using the surface response methodology. % Emulsifier agent and baking time were the selected independent variables for cake, as well as % emulsifier agent % chlorinated flour the variables selected for sponge cake. Three different level of each variable summing up thirteen experimental formulae of each product were assessed to optimize the variables that could have some influence in the sensory characteristics of these dietetic products. The total sensory quality was determined for both dietetic products using the composite scoring test and a panel of 18 trained judges. Looking at the contour graphic and considering economic aspects the best combination of variables for cake formulation was 2% emulsifier agent and 48 minutes for baking time, With respect to sponge cake, the best combination was 6% emulsifier agent and 48% chlorinated flour. Shelf life studies showed that both dietetic formulations remained stable during storage conditions of 75 days at 30 degrees C. During this period, significant differences in sensory characteristics were not found (p pastry products had good acceptability, and open up marketing opportunities for new products with potential health benefits to consumers.

  8. Facile Colorimetric Determination of Duloxetine in Formulations ...

    African Journals Online (AJOL)

    ... the determination of duloxetine hydrochloride (DX). Methods: Ion-pair spectrophotometric method was employed for the determination of duloxetine hydrochloride (DX) in bulk and pharmaceutical formulations using acidic dye methyl orange (MO) as ion-pairing agent at pH 4 (phthalate buffer). The yellow ion-pair complex ...

  9. Engaged Problem Formulation in IS Research

    DEFF Research Database (Denmark)

    Nielsen, Peter Axel; Persson, John Stouby

    2016-01-01

    problems requires a more substantial engagement with the different stakeholders, especially when their problems are ill structured and situated in complex organizational settings. On this basis, we present an engaged approach to formulating IS problems with, not for, IS practitioners. We have come...

  10. Effects of Methionine Containing Paracetamol Formulation on ...

    African Journals Online (AJOL)

    Effects of Methionine Containing Paracetamol Formulation on Serum Vitamins and Trace Elements in Male Rats. AA Iyanda, JI Anetor, DP Oparinde, FAA Adeniyi. Abstract. Methionine is an effective antidote in the treatment of paracetamol-induced toxicity but at large doses it has been reported to induce or aggravate a ...

  11. State-Space Formulation for Circuit Analysis

    Science.gov (United States)

    Martinez-Marin, T.

    2010-01-01

    This paper presents a new state-space approach for temporal analysis of electrical circuits. The method systematically obtains the state-space formulation of nondegenerate linear networks without using concepts of topology. It employs nodal/mesh systematic analysis to reduce the number of undesired variables. This approach helps students to…

  12. Yang-Mills formulation of interacting strings

    International Nuclear Information System (INIS)

    Chan Hongmo; Tsou Sheungtsun

    1988-06-01

    A suggestion that the theory of interacting open bosonic string be reformulated as a generalised Yang-Mills theory is further elucidated. Moreover, a serious reservation regarding the ordering of operators in the earlier 'proof' of equivalence between the new and standard formulations is now removed. (author)

  13. Initial value formulation of higher derivative gravity

    International Nuclear Information System (INIS)

    Noakes, D.R.

    1983-01-01

    The initial value problem is considered for the conformally coupled scalar field and higher derivative gravity, by expressing the equations of each theory in harmonic coordinates. For each theory it is shown that the (vacuum) equations can take the form of a diagonal hyperbolic system with constraints on the initial data. Consequently these theories possess well-posed initial value formulations

  14. Release Properties of Paracetamol Granulationa Formulated with ...

    African Journals Online (AJOL)

    Theobroma cacao gum, TCG was derived as a dry powder from fresh fruits of Theobroma cacao. Various granulations of paracetamol were prepared with TCG at the concentrations of 0.5 – 4% w/w. Similar formulations were prepared using sodium carboxymethyl cellulose, SCMC and acacia gums as standards. In each ...

  15. Probabilites in the general boundary formulation

    Energy Technology Data Exchange (ETDEWEB)

    Oeckl, Robert [Instituto de Matematicas, UNAM, Campus Morelia, C.P. 58190, Morelia, Michoacan (Mexico)

    2007-05-15

    We give an introductory account of the general boundary formulation of quantum theory. We refine its probability interpretation and emphasize a conceptual and historical perspective. We give motivations from quantum gravity and illustrate them with a scenario for describing gravitons in quantum gravity.

  16. On fictitious domain formulations for Maxwell's equations

    DEFF Research Database (Denmark)

    Dahmen, W.; Jensen, Torben Klint; Urban, K.

    2003-01-01

    We consider fictitious domain-Lagrange multiplier formulations for variational problems in the space H(curl: Omega) derived from Maxwell's equations. Boundary conditions and the divergence constraint are imposed weakly by using Lagrange multipliers. Both the time dependent and time harmonic formu...

  17. Necessity of rethinking oral pediatric formulations

    DEFF Research Database (Denmark)

    Bar-Shalom, Daniel

    2014-01-01

    by all patient groups, is needed, and an automated compounding concept is proposed. The finishing of the formulation is done at the dispensing pharmacy using an automated process. The individual components (pudding-like carrier, microencapsulated drug, and the dispensing robot and its software...

  18. A parcel formulation for Hamiltonian layer models

    NARCIS (Netherlands)

    Bokhove, Onno; Oliver, M.

    Starting from the three-dimensional hydrostatic primitive equations, we derive Hamiltonian N-layer models with isentropic tropospheric and isentropic or isothermal stratospheric layers. Our construction employs a new parcel Hamiltonian formulation which describes the fluid as a continuum of

  19. Clinical pharmacology of novel anticancer drug formulations

    NARCIS (Netherlands)

    Stuurman, F.E.

    2013-01-01

    Studies outlined in this thesis describe the impact of drug formulations on pharmacology of anticancer drugs. It consists of four parts and starts with a review describing the mechanisms of low oral bioavailability of anti-cancer drugs and strategies for improvement of the bioavailability. The

  20. Comparative evaluation of organic formulations of Pseudomonas ...

    African Journals Online (AJOL)

    An experiment was conducted in the laboratory and farm of the Department of Biotechnology, Gauhati University, to explore the potentiality of various organic formulations of Pseudomonas fluorescens (Pf) and to manage bacterial wilt disease of brinjal (Solanum melongena L.) under local conditions. Different organic ...