WorldWideScience

Sample records for full-field flat panel

  1. Measurement of effective detective quantum efficiency for a photon counting scanning mammography system and comparison with two flat panel full-field digital mammography systems

    Science.gov (United States)

    Wood, Tim J.; Moore, Craig S.; Saunderson, John R.; Beavis, Andrew W.

    2018-01-01

    Effective detective quantum efficiency (eDQE) describes the resolution and noise properties of an imaging system along with scatter and primary transmission, all measured under clinically appropriate conditions. Effective dose efficiency (eDE) is the eDQE normalised to mean glandular dose and has been proposed as a useful metric for the optimisation of clinical imaging systems. The aim of this study was to develop a methodology for measuring eDQE and eDE on a Philips microdose mammography (MDM) L30 photon counting scanning system, and to compare performance with two conventional flat panel systems. A custom made lead-blocker was manufactured to enable the accurate determination of dose measurements, and modulation transfer functions were determined free-in-air at heights of 2, 4 and 6 cm above the breast support platform. eDQE were calculated for a Philips MDM L30, Hologic Dimensions and Siemens Inspiration digital mammography system for 2, 4 and 6 cm thick poly(methyl methacrylate) (PMMA). The beam qualities (target/filter and kilovoltage) assessed were those selected by the automatic exposure control, and anti-scatter grids were used where available. Measurements of eDQE demonstrate significant differences in performance between the slit- and scan-directions for the photon counting imaging system. MTF has been shown to be the limiting factor in the scan-direction, which results in a rapid fall in eDQE at mid-to-high spatial frequencies. A comparison with two flat panel mammography systems demonstrates that this may limit image quality for small details, such as micro-calcifications, which correlates with a more conventional image quality assessment with the CDMAM phantom. eDE has shown the scanning photon counting system offers superior performance for low spatial frequencies, which will be important for the detection of large low contrast masses. Both eDQE and eDE are proposed as useful metrics that should enable optimisation of the Philips MDM L30.

  2. Damage assessment in a sandwich panel based on full-field vibration measurements

    Science.gov (United States)

    Seguel, F.; Meruane, V.

    2018-03-01

    Different studies have demonstrated that vibration characteristics are sensitive to debonding in composite structures. Nevertheless, one of the main restrictions of vibration measurements is the number of degrees of freedom that can be acquired simultaneously, which restricts the size of the damage that can be identified. Recent studies have shown that it is possible to use high-speed three-dimensional (3-D) digital image correlation (DIC) techniques for full-field vibration measurements. With this technique, it is possible to take measurements at thousands of points on the surface of a structure with a single snapshot. The present article investigates the application of full-field vibration measurements in the debonding assessment of an aluminium honeycomb sandwich panel. Experimental data from an aluminium honeycomb panel containing different damage scenarios is acquired by a high-speed 3-D DIC system; four methodologies to compute damage indices are evaluated: mode shape curvatures, uniform load surface, modal strain energy and gapped smoothing.

  3. Flat panel planar optic display

    Energy Technology Data Exchange (ETDEWEB)

    Veligdan, J.T. [Brookhaven National Lab., Upton, NY (United States). Dept. of Advanced Technology

    1994-11-01

    A prototype 10 inch flat panel Planar Optic Display, (POD), screen has been constructed and tested. This display screen is comprised of hundreds of planar optic class sheets bonded together with a cladding layer between each sheet where each glass sheet represents a vertical line of resolution. The display is 9 inches wide by 5 inches high and approximately 1 inch thick. A 3 milliwatt HeNe laser is used as the illumination source and a vector scanning technique is employed.

  4. Flat panel display - Impurity doping technology for flat panel displays

    Energy Technology Data Exchange (ETDEWEB)

    Suzuki, Toshiharu [Advanced Technology Planning, Sumitomo Eaton Nova Corporation, SBS Tower 9F, 10-1, Yoga 4-chome, Setagaya-ku, 158-0097 Tokyo (Japan)]. E-mail: suzuki_tsh@senova.co.jp

    2005-08-01

    Features of the flat panel displays (FPDs) such as liquid crystal display (LCD) and organic light emitting diode (OLED) display, etc. using low temperature poly-Si (LTPS) thin film transistors (TFTs) are briefly reviewed comparing with other FPDs. The requirements for fabricating TFTs used for high performance FPDs and system on glass (SoG) are addressed. This paper focuses on the impurity doping technology, which is one of the key technologies together with crystallization by laser annealing, formation of high quality gate insulator and gate-insulator/poly-Si interface. The issues to be solved in impurity doping technology for state of the art and future TFTs are clarified.

  5. Flat panel display - Impurity doping technology for flat panel displays

    International Nuclear Information System (INIS)

    Suzuki, Toshiharu

    2005-01-01

    Features of the flat panel displays (FPDs) such as liquid crystal display (LCD) and organic light emitting diode (OLED) display, etc. using low temperature poly-Si (LTPS) thin film transistors (TFTs) are briefly reviewed comparing with other FPDs. The requirements for fabricating TFTs used for high performance FPDs and system on glass (SoG) are addressed. This paper focuses on the impurity doping technology, which is one of the key technologies together with crystallization by laser annealing, formation of high quality gate insulator and gate-insulator/poly-Si interface. The issues to be solved in impurity doping technology for state of the art and future TFTs are clarified

  6. Laser illuminated flat panel display

    Energy Technology Data Exchange (ETDEWEB)

    Veligdan, J.T.

    1995-12-31

    A 10 inch laser illuminated flat panel Planar Optic Display (POD) screen has been constructed and tested. This POD screen technology is an entirely new concept in display technology. Although the initial display is flat and made of glass, this technology lends itself to applications where a plastic display might be wrapped around the viewer. The display screen is comprised of hundreds of planar optical waveguides where each glass waveguide represents a vertical line of resolution. A black cladding layer, having a lower index of refraction, is placed between each waveguide layer. Since the cladding makes the screen surface black, the contrast is high. The prototype display is 9 inches wide by 5 inches high and approximately I inch thick. A 3 milliwatt HeNe laser is used as the illumination source and a vector scanning technique is employed.

  7. Design scenarios for flat panel photobioreactors

    NARCIS (Netherlands)

    Slegers, P.M.; Wijffels, R.H.; Straten, van G.; Boxtel, van A.J.B.

    2011-01-01

    Evaluation of the potential of algae production for biofuel and other products at various locations throughout the world requires assessment of algae productivity under varying light conditions and different reactor layouts. A model was developed to predict algae biomass production in flat panel

  8. Design scenarios for flat panel photobioreactors

    International Nuclear Information System (INIS)

    Slegers, P.M.; Wijffels, R.H.; Straten, G. van; Boxtel, A.J.B. van

    2011-01-01

    Evaluation of the potential of algae production for biofuel and other products at various locations throughout the world requires assessment of algae productivity under varying light conditions and different reactor layouts. A model was developed to predict algae biomass production in flat panel photobioreactors using the interaction between light and algae growth for the algae species Phaeodactylum tricornutum and Thalassiosira pseudonana. The effect of location, variable sunlight and reactor layout on biomass production in single standing and parallel positioned flat panels was considered. Three latitudes were studied representing the Netherlands, France and Algeria. In single standing reactors the highest yearly biomass production is achieved in Algeria. During the year biomass production fluctuates the most in the Netherlands, while it is almost constant in Algeria. Several combinations of path lengths and biomass concentrations can result in the same optimal biomass production. The productivity in parallel place flat panels is strongly influenced by shading and diffuse light penetration between the panels. Panel orientation has a large effect on productivity and at higher latitudes the difference between north-south and east-west orientation may go up to 50%.

  9. Transparent Solar Concentrator for Flat Panel Display

    Science.gov (United States)

    Yeh, Chia-Hung; Chang, Fuh-Yu; Young, Hong-Tsu; Hsieh, Tsung-Yen; Chang, Chia-Hsiung

    2012-06-01

    A new concept of the transparent solar concentrator for flat panel display is experimentally demonstrated without adversely affecting the visual effects. The solar concentrator is based on a solar light-guide plate with micro prisms, not only increasing the absorption area of solar energy but also enhancing the conversion efficiency. The incident light is guided by the designed solar light-guide plate according to the total internal reflection (TIR), and converted into electrical power by photovoltaic solar cells. The designed transparent solar concentrator was made and measured with high transparency, namely 94.8%. The developed solar energy system for display can store energy and supply the bias voltage to light on two light-emitting diodes (LEDs) successfully.

  10. Flat-panel detectors in x-ray diagnosis

    International Nuclear Information System (INIS)

    Spahn, M.; Heer, V.; Freytag, R.

    2003-01-01

    For all application segments X-ray systems with flat-panel detectors increasingly enter the market. In digital radiography, mammography and cardiologic angiography flat-panel detectors are already well established while they are made ready for market introduction in general angiography and fluoroscopy. Two flat-panel detector technologies are available. One technology is based on an indirect conversion process of X-rays while the other one uses a direct conversion method.For radiography and dynamic applications the indirect method provides substantial advantages, while the direct method has some benefits for mammography. In radiography and mammography flat-panel detectors lead to clear improvements with respect to workflow, image quality and dose reduction potentials. These improvements are fostered by the immediate availability of the image, the large dynamic range and the high sensitivity to X-rays. New applications and the use of complex image processing algorithms have the potential to enlarge the present diagnostic range of applications.Up to now, image intensifiers are still the well-established technology for angiography and fluoroscopy. Nevertheless flat-panel detectors begin to enter this field, especially in cardiologic angiography.Characteristics of flat-panel detectors such as the availability of distortion-free images, the excellent contrast resolution, the large dynamic range, the high sensitivity to X-rays and the usability in magnetic fields provide the basis for improved and new diagnostic and interventional methods. (orig.) [de

  11. Flat or curved thin optical display panel

    Science.gov (United States)

    Veligdan, J.T.

    1995-01-10

    An optical panel includes a plurality of waveguides stacked together, with each waveguide having a first end and an opposite second end. The first ends collectively define a first face, and the second ends collectively define a second face of the panel. The second face is disposed at an acute face angle relative to the waveguides to provide a panel which is relatively thin compared to the height of the second face. In an exemplary embodiment for use in a projection TV, the first face is substantially smaller in height than the second face and receives a TV image, with the second face defining a screen for viewing the image enlarged. 7 figures.

  12. Multiple Site Damage in Flat Panel Testing

    National Research Council Canada - National Science Library

    Shrage, Daniel

    2000-01-01

    This report aimed to experimentally verify analytical models that predict the residual strength of representative aircraft structures, such as wide panels, that are subjected to Multiple Site Damage (MSD...

  13. Color quality management in advanced flat panel display engines

    Science.gov (United States)

    Lebowsky, Fritz; Neugebauer, Charles F.; Marnatti, David M.

    2003-01-01

    During recent years color reproduction systems for consumer needs have experienced various difficulties. In particular, flat panels and printers could not reach a satisfactory color match. The RGB image stored on an Internet server of a retailer did not show the desired colors on a consumer display device or printer device. STMicroelectronics addresses this important color reproduction issue inside their advanced display engines using novel algorithms targeted for low cost consumer flat panels. Using a new and genuine RGB color space transformation, which combines a gamma correction Look-Up-Table, tetrahedrization, and linear interpolation, we satisfy market demands.

  14. Diffractive flat panel solar concentrators of a novel design

    NARCIS (Netherlands)

    De Jong, T.M.; de Boer, D.K.G.; Bastiaansen, C.W.M.

    2016-01-01

    A novel design for a flat panel solar concentrator is presented which is based on a light guide with a grating applied on top that diffracts light into total internal reflection. By combining geometrical and diffractive optics the geometrical concentration ratio is optimized according to the

  15. Present and future of flat panel detectors in the world

    International Nuclear Information System (INIS)

    Inamura, Kiyonari

    2002-01-01

    Present status of development of flat panel detectors and their clinical application in the world have been surveyed, and future trends are also explored especially in the field of material researches and methods of manufacturing. Also the importance of role of medical physicists on user side is described because characteristic physics measurement of a detector assembly is unavoidable and essential in quality assurance in clinical routine and acceptance test in hospitals. Even though physics measurements and clinical evaluations on flat panel detectors have shown remarkable progress and advances in these several years, future problems of cost down in manufacturing and quality assurance to prevent individual differences between detector assemblies must be resolved. Results of evaluation in mammography, chest radiography, fluoroscopy for cardiovascular examination, bone tumor examination and radiotherapy application indicate that flat panel detectors are future promising materials. Their systematic operation is contributing to heighten accuracy of image examinations and preciseness of radiation therapy. Encouragement to medical physicists relevant to flat panel detectors is also raised in this paper. (author)

  16. IMac G4/800 (Flat Panel)

    CERN Multimedia

    2002-01-01

    Apple introduced the iMac G4/800 on January 7, 2002. The total cost was about $2000 (base price of $1799 plus RAM upgrade). The iMac G4/800 has an 800 MHz G4 processor. The G4/800 has the following ports: three USB 1.1 ports, two Fire Wire 400-Mbps ports, one RJ-45, 10/100BASE-T Ethernet port, one RJ-11 56K V.90 modem port, one Mini-VGA output port, one speaker jack, and one headphone jack. There is a built in microphone set on the front of the monitor in the bottom left corner. There is a single internal SuperDrive capable of reading and writing CDs and DVDs. The disk drive is on the front of the computer. It opens by pushing the disk drive button on the iMac's keyboard. The monitor size is 15 inches. The G4/800 has a NVIDIA GeForce2 MX graphics processor with AGP 2X support that provides 32 MB of dedicated Double Data Rate (DDR) video memory. Native resolution is 1024 x 768, but the built in monitor is also capable of 640 x 480 and 800 x 600. RAM can be changed by removing a panel on the bottom of the chas...

  17. Software Simulates Sight: Flat Panel Mura Detection

    Science.gov (United States)

    2008-01-01

    In the increasingly sophisticated world of high-definition flat screen monitors and television screens, image clarity and the elimination of distortion are paramount concerns. As the devices that reproduce images become more and more sophisticated, so do the technologies that verify their accuracy. By simulating the manner in which a human eye perceives and interprets a visual stimulus, NASA scientists have found ways to automatically and accurately test new monitors and displays. The Spatial Standard Observer (SSO) software metric, developed by Dr. Andrew B. Watson at Ames Research Center, measures visibility and defects in screens, displays, and interfaces. In the design of such a software tool, a central challenge is determining which aspects of visual function to include while accuracy and generality are important, relative simplicity of the software module is also a key virtue. Based on data collected in ModelFest, a large cooperative multi-lab project hosted by the Optical Society of America, the SSO simulates a simplified model of human spatial vision, operating on a pair of images that are viewed at a specific viewing distance with pixels having a known relation to luminance. The SSO measures the visibility of foveal spatial patterns, or the discriminability of two patterns, by incorporating only a few essential components of vision. These components include local contrast transformation, a contrast sensitivity function, local masking, and local pooling. By this construction, the SSO provides output in units of "just noticeable differences" (JND) a unit of measure based on the assumed smallest difference of sensory input detectable by a human being. Herein is the truly amazing ability of the SSO, while conventional methods can manipulate images, the SSO models human perception. This set of equations actually defines a mathematical way of working with an image that accurately reflects the way in which the human eye and mind behold a stimulus. The SSO is

  18. Development of Surfaces Optically Suitable for Flat Solar Panels

    Science.gov (United States)

    Desmet, D.; Jason, A.

    1978-01-01

    Three areas of research in the development of flat solar panels are described. (1) A reflectometer which can separately evaluate the spectral and diffuse reflectivities of surfaces was developed. The reflectometer has a phase locked detection system. (2) A coating composed of strongly bound copper oxide that is formed by an etching process performed on an aluminum alloy with high copper content was also developed. Because of this one step fabrication process, fabrication costs are expected to be small. (3) A literature search was conducted and conclusions on the required optical properties of flat plate solar collectors are presented.

  19. Digital radiography with large-area flat-panel detectors

    International Nuclear Information System (INIS)

    Kotter, E.; Langer, M.

    2002-01-01

    Large-area flat-panel detectors with active readout mechanisms have been on the market for the past 2 years. This article describes different detector technologies. An important distinction is made between detectors with direct and those with indirect conversion of X-rays into electrical charges. Detectors with indirect conversion are built with unstructured or structured scintillators, the latter resulting in less lateral diffusion of emitted light. Some important qualities of flat-panel detectors are discussed. The first phantom and clinical studies published report an image quality at least comparable to that of screen-film systems and a potential for dose reduction. The available studies are summarised in this article. (orig.)

  20. Flat panel planar optic display. Revision 4/95

    Energy Technology Data Exchange (ETDEWEB)

    Veligdan, J.T.

    1995-05-01

    A prototype 10 inch flat panel Planar Optic display, (POD), screen has been constructed and tested. This display screen is comprised of hundreds of planar optic glass sheets bonded together with a cladding layer between each sheet where each glass sheet represents a vertical line of resolution. The display is 9 inches wide by 5 inches high and approximately 1 inch thick. A 3 milliwatt HeNe laser is used as the illumination source and a vector scanning technique is employed.

  1. Diffractive flat panel solar concentrators of a novel design.

    Science.gov (United States)

    de Jong, Ties M; de Boer, Dick K G; Bastiaansen, Cees W M

    2016-07-11

    A novel design for a flat panel solar concentrator is presented which is based on a light guide with a grating applied on top that diffracts light into total internal reflection. By combining geometrical and diffractive optics the geometrical concentration ratio is optimized according to the principles of nonimaging optics, while the thickness of the device is minimized due to the use of total internal reflection.

  2. The digital flat-panel X-Ray detectors

    International Nuclear Information System (INIS)

    Risticj, S. Goran

    2013-01-01

    In a digital imaging system, the incident x-ray image must be sampled both in the spatial and intensity dimensions. In the spatial dimensions, samples are obtained as averages of the intensity over picture elements or pixels. In the intensity dimension, the signal is digitalized into one of a finite number of levels or bits. Two main types of digital flat-panel detectors are based on the direct conversion, which contains the photoconductor, and on indirect conversion, which contains phosphor. The basics of these detectors are given. Coupling traditional x-ray detection material such as photoconductors and phosphors with a large-area active-matrix readout structure forms the basis of flat panel x-ray images. Active matrix technology provides a new, highly efficient, real time method for electronically storing and measuring the product of the x-ray interaction stage whether the product is visible wavelength photons or electrical charges. The direct and indirect detectors, made as the active-matrix flat-panel detectors containing sensing/storage elements, switching elements (diodes or thin film transistors (TFTS)) and image processing module, are described. Strengths and limitations of stimulable phosphors are discussed. The main advantages and disadvantages of mentioned x-ray detectors are also analyzed. (Author)

  3. Supersonic Panel Flutter Test Results for Flat Fiber-Glass Sandwich Panels with Foamed Cores

    Science.gov (United States)

    Tuovila, W. J.; Presnell, John G., Jr.

    1961-01-01

    Flutter tests have been made on flat panels having a 1/4 inch-thick plastic-foam core covered with thin fiber-glass laminates. The testing was done in the Langley Unitary Plan wind tunnel at Mach numbers from 1.76 t o 2.87. The flutter boundary for these panels was found to be near the flutter boundary of thin metal panels when compared on the basis of an equivalent panel stiffness. The results also demonstrated that the depth of the cavity behind the panel has a pronounced influence on flutter. Changing the cavity depth from 1 1/2 inches to 1/2 inch reduced the dynamic pressure at start of flutter by 40 percent. No flutter was obtained when the spacers on the back of the panel were against the bottom of the cavity.

  4. Evaluation of flat panel PMT for gamma ray imaging

    International Nuclear Information System (INIS)

    Pani, R.; Cinti, M.N.; Pellegrini, R.; Trotta, C.; Trotta, G.; Montani, L.; Ridolfi, S.; Garibaldi, F.; Scafe, R.; Belcari, N.; Del Guerra, A.

    2003-01-01

    The first position sensitive PMT, Hamamatsu R2486, developed in 1985, represented a strong technological advance for gamma-ray imaging. Hamamatsu H8500 Flat Panel PMT is the last generation position sensitive PMT: extremely compact with 2 in. active area. Its main features are: minimum peripheral dead zone (1 mm) and height of 12 mm. It was designed to be assembled in array to cover large detection area. It can represent a technical revolution for many applications in the field of gamma-ray imaging as for example nuclear medicine. This tube is based on metal channel dynode for charge multiplication and 8x8 anodes for charge collection and position calculation. In this paper we present a preliminary evaluation of the imaging performances addressed to nuclear medicine application. To this aim we have taken into account two different electronic readouts: resistive chain with Anger Camera principle and multianode readout. Flat panel PMT was coupled to CsI(Tl) and NaI(Tl) scintillation arrays. The results were also compared with the first generation PSPMT

  5. Reconstruction of Spectra Using X-ray Flat Panel Detector; Reconstruccion de Espectros de Rayos X Utilizando un Detector Flat Panel

    Energy Technology Data Exchange (ETDEWEB)

    Gallardo, S.; Querol, A.; Pozuelo, F.; Juste, B.; Rodenas, J.; Verdu, G.

    2013-07-01

    In this work, we used a flat panel detector with a wedge of PMMA for absorbed dose curve for given working conditions of X-ray tube The relationship between absorbed dose curve recorded by the flat panel and primary X-ray spectrum is defined by a response function that can be obtained using the Monte Carlo method, namely the MCNP5 code. However there are some problems that affect the applicability of this method such as: flat panel characteristics and the characteristics of the physical process (ill-conditioned problem). Both aspects are discussed in this paper.

  6. Advances in infrastructure support for flat panel display manufacturing

    Science.gov (United States)

    Bardsley, James N.; Ciesinski, Michael F.; Pinnel, M. Robert

    1997-07-01

    The success of the US display industry, both in providing high-performance displays for the US Department of Defense at reasonable cost and in capturing a significant share of the global civilian market, depends on maintaining technological leadership and on building efficient manufacturing capabilities. The US Display Consortium (USDC) was set up in 1993 by the US Government and private industry to guide the development of the infrastructure needed to support the manufacturing of flat panel displays. This mainly involves the supply of equipment and materials, but also includes the formation of partnerships and the training of a skilled labor force. Examples are given of successful development projects, some involving USDC participation, others through independent efforts of its member companies. These examples show that US-based companies can achieve leadership positions in this young and rapidly growing global market.

  7. Carbon Nanotube Thin Film Transistors for Flat Panel Display Application.

    Science.gov (United States)

    Liang, Xuelei; Xia, Jiye; Dong, Guodong; Tian, Boyuan; Peng, Lianmao

    2016-12-01

    Carbon nanotubes (CNTs) are promising materials for both high performance transistors for high speed computing and thin film transistors for macroelectronics, which can provide more functions at low cost. Among macroelectronics applications, carbon nanotube thin film transistors (CNT-TFT) are expected to be used soon for backplanes in flat panel displays (FPDs) due to their superior performance. In this paper, we review the challenges of CNT-TFT technology for FPD applications. The device performance of state-of-the-art CNT-TFTs are compared with the requirements of TFTs for FPDs. Compatibility of the fabrication processes of CNT-TFTs and current TFT technologies are critically examined. Though CNT-TFT technology is not yet ready for backplane production line of FPDs, the challenges can be overcome by close collaboration between research institutes and FPD manufacturers in the short term.

  8. Flat-panel video resolution LED display system

    Science.gov (United States)

    Wareberg, P. G.; Kennedy, D. I.

    The system consists of a 128 x 128 element X-Y addressable LED array fabricated from green-emitting gallium phosphide. The LED array is interfaced with a 128 x 128 matrix TV camera. Associated electronics provides for seven levels of grey scale above zero with a grey scale ratio of square root of 2. Picture elements are on 0.008 inch centers resulting in a resolution of 125 lines-per-inch and a display area of approximately 1 sq. in. The LED array concept lends itself to modular construction, permitting assembly of a flat panel screen of any desired size from 1 x 1 inch building blocks without loss of resolution. A wide range of prospective aerospace applications exist extending from helmet-mounted systems involving small dedicated arrays to multimode cockpit displays constructed as modular screens. High-resolution LED arrays are already used as CRT replacements in military film-marking reconnaissance applications.

  9. Quantitative digital radiography with two dimensional flat panels

    International Nuclear Information System (INIS)

    Dinten, J.M.; Robert-Coutant, C.; Darboux, M.

    2003-01-01

    Purpose: Attenuation law relates radiographic images to irradiated object thickness and chemical composition. Film radiography exploits qualitatively this property for diagnosis. Digital radiographic flat panels present large dynamic range, reproducibility and linearity properties which open the gate for quantification. We will present, through two applications (mammography and bone densitometry), an approach to extract quantitative information from digital 2D radiographs. Material and method: The main difficulty for quantification is X-rays scatter, which superimposes to acquisition data. Because of multiple scatterings and 3D geometry dependence, it cannot be directly exploited through an exact analytical model. Therefore we have developed an approach for its estimation and subtraction from medical radiographs, based on approximations and derivations of analytical models of scatter formation in human tissues. Results: In digital mammography, the objective is to build a map of the glandular tissue thickness. Its separation from fat tissue is based on two equations: height of compression and attenuation. This last equation needs X-Rays scatter correction. In bone densitometry, physicians look for quantitative bone mineral density. Today, clinical DEXA systems use collimated single or linear detectors to eliminate scatter. This scanning technology induces poor image quality. By applying our scatter correction approach, we have developed a bone densitometer using a digital flat panel (Lexxos, DMS). It provides with accurate and reproducible measurements while presenting radiological image quality. Conclusion: These applications show how information processing, and especially X-Rays scatter processing, enables to extract quantitative information from digital radiographs. This approach, associated to Computer Aided Diagnosis algorithms or reconstructions algorithms, gives access to useful information for diagnosis. (author)

  10. Synchrotron applications of an amorphous silicon flat-panel detector

    International Nuclear Information System (INIS)

    Lee, J. H.; Can Aydiner, C.; Almer, J.; Bernier, J.; Chapman, K. W.; Chupas, P. J.; Haeffner, D.; Kump, K.; Lee, P. L.; Lienert, U.; Miceli, A.; Vera, G.; LANL; GE Healthcare

    2008-01-01

    A GE Revolution 41RT flat-panel detector (GE 41RT) from GE Healthcare (GE) has been in operation at the Advanced Photon Source for over two years. The detector has an active area of 41 cm x 41 cm with 200 (micro)m x 200 (micro)m pixel size. The nominal working photon energy is around 80 keV. The physical set-up and utility software of the detector system are discussed in this article. The linearity of the detector response was measured at 80.7 keV. The memory effect of the detector element, called lag, was also measured at different exposure times and gain settings. The modulation transfer function was measured in terms of the line-spread function using a 25 (micro)m x 1 cm tungsten slit. The background (dark) signal, the signal that the detector will carry without exposure to X-rays, was measured at three different gain settings and with exposure times of 1 ms to 15 s. The radial geometric flatness of the sensor panel was measured using the diffraction pattern from a CeO 2 powder standard. The large active area and fast data-capturing rate, i.e. 8 frames s -1 in radiography mode, 30 frames s -1 in fluoroscopy mode, make the GE 41RT one of a kind and very versatile in synchrotron diffraction. The loading behavior of a Cu/Nb multilayer material is used to demonstrate the use of the detector in a strain-stress experiment. Data from the measurement of various samples, amorphous SiO 2 in particular, are presented to show the detector effectiveness in pair distribution function measurements

  11. Flat Panel PMT: advances in position sensitive photodetection

    International Nuclear Information System (INIS)

    Pani, R.; Pellegrini, R.; Trotta, C.; Cinti, M.N.; Bennati, P.; Trotta, G.; Iurlaro, G.; Montani, L.; Ridolfi, S.; Cusanno, F.; Garibaldi, F.

    2003-01-01

    Over the last ten years there was being a strong advancement in photodetection. Different application fields are involved in their use in particular high energy physics, astrophysics and nuclear medicine. They usually work by coupling a scintillation crystal and more recent scintillation arrays with pixel size as small as 0.5 mm. PSPMT represents today the most ready technology for photodetection with large detection areas and very high spatial resolution. Flat panel PMT represents the last technological advancement. Its dimension is 50x50 mm 2 with a narrow peripheral dead zone (0.5 mm final goal). Its compactness allow to assemble different modules closely packed, achieving large detection areas with an effective active area of 97%. In this paper we analyze the imaging performances of PSPMT by coupling two scintillation arrays and by light spot scanning of photocathode to evaluate the linearity position response, spatial resolution and uniformity gain response as a function of light distribution spread and the number of photoelectrons generated on photocathode. The results point out a very narrow PMT intrinsic charge spread and low cross-talk between anodes. Energy resolution and spatial resolution show a good linearity with DRF variation. An unexpected intra-anode gain variation is carried out. In this paper we present the results obtained with this PSPMT regarding imaging performances principally addressed to nuclear medicine application

  12. Review of flat panel display programs and defense applications

    Science.gov (United States)

    Gnade, Bruce; Schulze, Raymond; Henderson, Girardeau L.; Hopper, Darrel G.

    1997-07-01

    Flat panel display research has comprised a substantial portion of the national investment in new technology for economic and national security for the past nine years. These investments have ben made principally via several Defense Advanced Research Projects Agency (DARPA) programs, known collectively as the continuing High Definition Systems Program, and the Office of the Secretary of Defense Production Act Title III Program. Using input from the Army, Navy, and Air Force to focus research and identify insertion opportunities, DARPA and the Title III Program Office have made investments to develop the national technology base and manufacturing infrastructure necessary to meet the twin challenge of providing affordable displays in current systems and enabling the DoD strategy of winning future conflicts by getting more information to all participants during the battle. These research programs are reviewed and opportunities for applications are described. Future technology development, transfer, and transition requirements are identified. Strategy and vision are documented to assist the identification of areas meriting further consideration.

  13. Evaluation of a flat-panel detector system

    International Nuclear Information System (INIS)

    Sato, Masami; Eguchi, Yoichi; Yamada, Kinichi; Kaga, Yuji; Endo, Yutaka; Yamazaki, Tatsuya

    2001-01-01

    We evaluated the imaging performance of a flat-panel detector digital radiography system (CXDI-11 X-ray Digital Camera, Canon Inc.) and a computed radiography system (FCR9000C-HQ, Fuji Film). The characteristics of the two detectors and of the overall systems were compared. This included evaluation and comparison of the fundamental physical characteristics, including x-ray response curve, modulation transfer function (MTF), Wiener spectra, noise-equivalent quanta, and x-ray tube voltage-dependent detector response. Overall system performance was evaluated using receiver operating characteristic (ROC) analysis. The results of the study showed that the dynamic range of the CXDI-11 measured relative to the input x-ray flux was 10 3 , similar to that of the FCR9000C-HQ. Both systems showed similar final MTFs, although the pre-sampling MTF of the CXDI-11 was better than that of the FCR9000C-HQ. Noise analysis, based on noise-equivalent quanta and Wiener spectra, showed that for normal exposure conditions the CXDI-11 had superior performance. With both systems, x-ray response (system output/incident x-ray exposure) increased with increasing x-ray tube voltage. ROC analysis indicated that the CXDI-11 was superior in overall performance. (author)

  14. Digital chest radiography: flat-panel detectors or conventional radiographs

    International Nuclear Information System (INIS)

    Schaefer-Prokop, C.; Uffmann, M.; Sailer, J.; Kabalan, N.; Herold, C.; Prokop, M.

    2003-01-01

    Flat panel detectors are characterized by improved handling and increased dose efficiency. This allows for increasing of work flow efficiency and for reducing the exposure dose by about 50% compared to current systems with a sensitivity of 400. Whether the increased dose efficiency should be used to reduce acquisition dose or to increase image quality in the chest, will be shown by further clinical experience and will be also determined by the subjective preference of the radiologists. The decreased level of image noise opens new perspectives for image processing that way that elaborated multifrequency processing allows for optimizing the display of very small and low contrast structures that was so far limited by overlying image noise. Specialized applications of dual energy subtraction and temporal subtraction will also profit by the new detector technology and will be further driven forward in context with applications such as computed assisted diagnosis even though this is currently not yet broadly applied. Storage phosphor radiography still represents an important alternative technique based on its larger flexibility with respect to equipment configuration, its broader application options in intensive care and emergency radiology and due to economic reasons. These facts are further underlined by the fact that image quality also in storage phosphor radiography could be constantly increased by improving detector technology and image processing and consequently has a high standard. (orig.) [de

  15. Characteristics and applications of a flat panel computer tomography system

    International Nuclear Information System (INIS)

    Knollmann, F.; Valencia, R.; Obenauer, S.; Buhk, J.H.

    2006-01-01

    Purpose: to assess a new flat panel volume computed tomography (FP-VCT) with very high isotropic spatial resolution as well as high Z-axis coverage. Materials and Methods: The prototype of an FP-VCT scanner with a detector cell size of 0.2 mm was used for numerous phantom studies, specimen examinations, and animal research projects. Results: The high spatial resolution of the new system can be used to accurately determine solid tumor volume, thus allowing for earlier assessment of the therapeutic response. In animal experimentation, whole-body perfusion mapping of mice is feasible. The high spatial resolution also improves the classification of coronary artery atherosclerotic plaques in the isolated post mortem human heart. With the depiction of intramyocardial segments of the coronary arteries, investigations of myocardial collateral circulation are feasible. In skeletal applications, an accurate analysis of the smallest bony structures, e.g., petrous bone and dental preparations, can be successfully performed, as well as investigations of repetitive studies of fracture healing and the treatment of osteoporosis. Conclusion: The introduction of FP-VCT opens up new applications for CT, including the field of molecular imaging, which are highly attractive for future clinical applications. Present limitations include limited temporal resolution and necessitate further improvement of the system. (orig.)

  16. Flat-panel detectors: how much better are they?

    International Nuclear Information System (INIS)

    Seibert, J.A.

    2006-01-01

    Interventional and fluoroscopic imaging procedures for pediatric patients are becoming more prevalent because of the less-invasive nature of these procedures compared to alternatives such as surgery. Flat-panel X-ray detectors (FPD) for fluoroscopy are a new technology alternative to the image intensifier/TV (II/TV) digital system that has been in use for more than two decades. Two major FPD technologies have been implemented, based on indirect conversion of X-rays to light (using an X-ray scintillator) and then to proportional charge (using a photodiode), or direct conversion of X-rays into charge (using a semiconductor material) for signal acquisition and digitization. These detectors have proved very successful for high-exposure interventional procedures but lack the image quality of the II/TV system at the lowest exposure levels common in fluoroscopy. The benefits for FPD image quality include lack of geometric distortion, little or no veiling glare, a uniform response across the field-of-view, and improved ergonomics with better patient access. Better detective quantum efficiency indicates the possibility of reducing the patient dose in accordance with ALARA principles. However, first-generation FPD devices have been implemented with less than adequate acquisition flexibility (e.g., lack of tableside controls/information, inability to easily change protocols) and the presence of residual signals from previous exposures, and additional cost of equipment and long-term maintenance have been serious impediments to purchase and implementation. Technological advances of second generation and future hybrid FPD systems should solve many current issues. The answer to the question ''how much better are they?'' is ''significantly better'', and they are certainly worth consideration for replacement or new implementation of an imaging suite for pediatric fluoroscopy. (orig.)

  17. Scan equalization digital radiography (SEDR) implemented with an amorphous selenium flat-panel detector: initial experience

    Energy Technology Data Exchange (ETDEWEB)

    Liu Xinming; Lai Chaojen; Chen Lingyun; Han Tao; Zhong Yuncheng; Shen Youtao; Wang Tianpeng; Shaw, Chris C [Department of Imaging Physics, Digital Imaging Research Laboratory, University of Texas M. D. Anderson Cancer Center, Houston, TX 77030-4009 (United States)], E-mail: xliu@di.mdacc.tmc.edu

    2009-11-21

    It is well recognized in projection radiography that low-contrast detectability suffers in heavily attenuating regions due to excessively low x-ray fluence to the image receptor and higher noise levels. Exposure equalization can improve image quality by increasing the x-ray exposure to heavily attenuating regions, resulting in a more uniform distribution of exposure to the detector. Image quality is also expected to be improved by using the slot-scan geometry to reject scattered radiation effectively without degrading primary x-rays. This paper describes the design of a prototype scan equalization digital radiography (SEDR) system implemented with an amorphous silicon (a-Si) thin-film transistor (TFT) array-based flat-panel detector. With this system, slot-scan geometry with alternate line erasure and readout (ALER) technique was used to achieve scatter rejection. A seven-segment beam height modulator assembly was mounted onto the fore collimator to regulate exposure regionally for chest radiography. The beam modulator assembly, consisting of micro linear motors, lead screw cartridge with lead (Pb) beam blockers attached, position feedback sensors and motor driver circuitry, has been tested and found to have an acceptable response for exposure equalization in chest radiography. An anthropomorphic chest phantom was imaged in the posterior-anterior (PA) view under clinical conditions. Scatter component, primary x-rays, scatter-to-primary ratios (SPRs) and primary signal-to-noise ratios (PSNRs) were measured in the SEDR images to evaluate the rejection and redistribution of scattered radiation, and compared with those for conventional full-field imaging with and without anti-scatter grid methods. SPR reduction ratios (SPRRRs, defined as the differences between the non-grid full-field SPRs and the reduced SPRs divided by the former) yielded approximately 59% for the full-field imaging with grid and 82% for the SEDR technique in the lungs, and 77% for the full-field

  18. Driver-Array Based Flat-Panel Loudspeakers: Theoretical Background and Design Guidelines

    Science.gov (United States)

    Anderson, David Allan

    This thesis relates to the simulation and design of flat-panel loudspeakers using moving-coil driver elements. A brief history of the industry is given, including a collection of products and patents from 1925 until the present, an overview of research papers, and a discussion of current products available. The mechanics of bending flat panels are developed with respect to localized driving forces, both in the frequency domain and the time domain as an impulse response. These simulations are compared to measurements on prototype panels. Additional resonant elements influence the behavior of the system: an optional ported rear enclosure and the resonant characteristics of the drivers. The governing equations for these systems are derived and solutions are implemented using equivalent mechanical circuits and numerical methods. The idea of using driver arrays to independently actuate modes of the panel is discussed at length with respect to modal addressability, modal spillover, and experimental validation. The numerical approach to determining the optimal driver placement for a given set of modes is derived and experimentally validated. An investigation of the acoustic behavior of flat panel loudspeakers is presented, using mechanical simulation results to predict the acoustic radiation. The simulations are compared to measurements and found to accurately predict important mechanical and acoustical behaviors. It is demonstrated that a driver array, with the proper biasing, is capable of creating a flat panel loudspeaker which acts more like a piston than a "diffuse radiator" flat panel loudspeaker. The techniques of "Modal Crossover Networks" are introduced, which use multi-band filters to bias the driver array differently for different frequency bands, optimized for audio reproduction. The question of how many drivers are necessary for a modal crossover network is addressed and found to be dependent on the estimated quality factor (Q) of the panel material and edge

  19. Improvement of illumination uniformity for LED flat panel light by using micro-secondary lens array.

    Science.gov (United States)

    Lee, Hsiao-Wen; Lin, Bor-Shyh

    2012-11-05

    LED flat panel light is an innovative lighting product in recent years. However, current flat panel light products still contain some drawbacks, such as narrow lighting areas and hot spots. In this study, a micro-secondary lens array technique was proposed and applied for the design of the light guide surface to improve the illumination uniformity. By using the micro-secondary lens array, the candela distribution of the LED flat panel light can be adjusted to similar to batwing distribution to improve the illumination uniformity. The experimental results show that the enhancement of the floor illumination uniformity is about 61%, and that of the wall illumination uniformity is about 20.5%.

  20. Recommendations for the performance rating of flat plate terrestrial photovoltaic solar panels

    Science.gov (United States)

    Treble, F. C.

    1976-01-01

    A review of recommendations for standardizing the performance rating of flat plate terrestrial solar panels is given to develop an international standard code of practice for performance rating. Required data to characterize the performance of a solar panel are listed. Other items discussed are: (1) basic measurement procedures; (2) performance measurement in natural sunlight and simulated sunlight; (3) standard solar cells; (4) the normal incidence method; (5) global method and (6) definition of peak power.

  1. Transparent Fingerprint Sensor System for Large Flat Panel Display

    Directory of Open Access Journals (Sweden)

    Wonkuk Seo

    2018-01-01

    Full Text Available In this paper, we introduce a transparent fingerprint sensing system using a thin film transistor (TFT sensor panel, based on a self-capacitive sensing scheme. An armorphousindium gallium zinc oxide (a-IGZO TFT sensor array and associated custom Read-Out IC (ROIC are implemented for the system. The sensor panel has a 200 × 200 pixel array and each pixel size is as small as 50 μm × 50 μm. The ROIC uses only eight analog front-end (AFE amplifier stages along with a successive approximation analog-to-digital converter (SAR ADC. To get the fingerprint image data from the sensor array, the ROIC senses a capacitance, which is formed by a cover glass material between a human finger and an electrode of each pixel of the sensor array. Three methods are reviewed for estimating the self-capacitance. The measurement result demonstrates that the transparent fingerprint sensor system has an ability to differentiate a human finger’s ridges and valleys through the fingerprint sensor array.

  2. Transparent Fingerprint Sensor System for Large Flat Panel Display.

    Science.gov (United States)

    Seo, Wonkuk; Pi, Jae-Eun; Cho, Sung Haeung; Kang, Seung-Youl; Ahn, Seong-Deok; Hwang, Chi-Sun; Jeon, Ho-Sik; Kim, Jong-Uk; Lee, Myunghee

    2018-01-19

    In this paper, we introduce a transparent fingerprint sensing system using a thin film transistor (TFT) sensor panel, based on a self-capacitive sensing scheme. An armorphousindium gallium zinc oxide (a-IGZO) TFT sensor array and associated custom Read-Out IC (ROIC) are implemented for the system. The sensor panel has a 200 × 200 pixel array and each pixel size is as small as 50 μm × 50 μm. The ROIC uses only eight analog front-end (AFE) amplifier stages along with a successive approximation analog-to-digital converter (SAR ADC). To get the fingerprint image data from the sensor array, the ROIC senses a capacitance, which is formed by a cover glass material between a human finger and an electrode of each pixel of the sensor array. Three methods are reviewed for estimating the self-capacitance. The measurement result demonstrates that the transparent fingerprint sensor system has an ability to differentiate a human finger's ridges and valleys through the fingerprint sensor array.

  3. Image quality analysis of vibration effects In C-arm-flat panel X-ray imaging

    NARCIS (Netherlands)

    Snoeren, R.M.; Kroon, J.N.; With, de P.H.N.

    2011-01-01

    The motion of C-arm scanning X-ray systems may result in vibrations of the imaging sub-system. In this paper, we connect C-arm system vibrations to Image Quality (IQ) deterioration for 2D angiography and 3D cone beam X-ray imaging, using large Flat Panel detectors. Vibrations will affect the

  4. On Energy Balance and Production Costs in Tubular and Flat Panel Photobioreactors

    NARCIS (Netherlands)

    Norsker, N.H.; Barbosa, M.J.; Vermue, M.H.; Wijffels, R.H.

    2012-01-01

    Reducing mixing in both flat panel and tubular photobioreactors can result in a positive net energy balance with state-of-the-art technology and Dutch weather conditions. In the tubular photobioreactor, the net energy balance becomes positive at velocities <0.3 ms-1, at which point the biomass

  5. Volumetry of human molars with flat panel-based volume CT in vitro

    NARCIS (Netherlands)

    Hannig, C.; Krieger, E.; Dullin, C.; Merten, H.A.; Attin, T.; Grabbe, E.; Heidrich, G.

    2006-01-01

    The flat panel-based volume computed tomography (fpVCT) is a new CT device applicable for experimental, three-dimensional evaluation of teeth at a resolution of about 150 microm in the high contrast region. The aim of this study was to investigate whether fpVCT was suitable for quantification of the

  6. Implementation of a program of quality assurance of image in an imaging system of flat panel portal

    International Nuclear Information System (INIS)

    Gomez Barrado, A.; Sanchez Jimenez, E.; Benitez, J. A.; Sanchez-Reyes, A.

    2013-01-01

    (IGRT) image-guided radiation therapy is the one in which images are used to locate the area of treatment. Modern irradiation systems are equipped with different modalities for obtaining images, such as flat panel systems, systems conebeam, tomoimagen, etc. This paper describes the start-up and the experience of a quality assurance program based on a flat panel portal Imaging System. (Author)

  7. Performance evaluation of flat panel detector in x-ray fluoroscopy

    International Nuclear Information System (INIS)

    Grewal, R.K.; Mclean, I.D.

    2004-01-01

    Full text: Flat panel detectors are currently replacing the conventional image intensifiers in R-F imaging. We evaluated the performance of a biplane cardiac imaging system (Siemens Axiom Artis dBC), the image acquisition was based on a 25 cm diagonal digital fiat panel detector. Performance characteristics included image quality, typical patient entrance dose and measurement of input to the surface of flat detector. The results were compared with conventional image intensifier systems (Siemens Hicor Unit and Toshiba DPF 2000 A Biplane Unit) used in cardiac imaging at Westmead. Image quality and dose measurements were performed following standard protocols using Westmead test object and 20 cm solid water as absorber in the beam. For measurement of input to the surface of flat detector, 2 mm copper was placed on the collimator. Radcal 3cc and 180 cc ion chambers were used for dose measurements. Image quality: Our measurements on flat panel system indicate that high contrast resolution and threshold contrast is not affected by changing field size. This is expected due to minimum loss of signal in the imaging chain of digital systems and the independence of detector pixel size with change in field of view. While low contrast resolution was found to be similar to conventional systems, high contrast resolution was significantly superior using flat detector system for large and intermediate field of view (25-28 1p/cm against 18-20). Typical patient dose as measured using flat detector system was similar to the conventional Toshiba pulsed fluoroscopy system( ∼ 3 - 8 mGy/min depending on the field size). This was 40-50 % lower than our old Siemens hicore unit. Input to the surface of flat detector was found to vary with field size as is the case with a conventional II system. As described elsewhere, although there is no necessity to increase exposure or video gain in a digital magnification, digital data interpolation process introduces noise. As a result system

  8. Full dynamic resolution low lower DA-Converters for flat panel displays

    Directory of Open Access Journals (Sweden)

    C. Saas

    2006-01-01

    Full Text Available It has been shown that stepwise charging can reduce the power dissipated in the source drivers of a flat panel display. However the solution presented only provided a dynamic resolution of 3 bits which is not sufficient for obtaining a full color resolution display. In this work a further development of the basic idea is presented. The stepwise charging is increased to 4 bits and supplemented by a current source to provide an output signal which represents an 8 bit value with sufficient accuracy. Within this work the application is an AM-OLED flat panel display, but the concept can easily be applied to other display technologies like TFT-LCD as well.

  9. A novel heuristic for optimization aggregate production problem: Evidence from flat panel display in Malaysia

    Science.gov (United States)

    Al-Kuhali, K.; Hussain M., I.; Zain Z., M.; Mullenix, P.

    2015-05-01

    Aim: This paper contribute to the flat panel display industry it terms of aggregate production planning. Methodology: For the minimization cost of total production of LCD manufacturing, a linear programming was applied. The decision variables are general production costs, additional cost incurred for overtime production, additional cost incurred for subcontracting, inventory carrying cost, backorder costs and adjustments for changes incurred within labour levels. Model has been developed considering a manufacturer having several product types, which the maximum types are N, along a total time period of T. Results: Industrial case study based on Malaysia is presented to test and to validate the developed linear programming model for aggregate production planning. Conclusion: The model development is fit under stable environment conditions. Overall it can be recommended to adapt the proven linear programming model to production planning of Malaysian flat panel display industry.

  10. Low-cost modular array-field designs for flat-panel and concentrator photovoltaic systems

    Science.gov (United States)

    Post, H. N.; Carmichael, D. C.; Alexander, G.; Castle, J. A.

    1982-09-01

    Described are the design and development of low-cost, modular array fields for flat-panel and concentrator photovoltaic (PV) systems. The objective of the work was to reduce substantially the cost of the array-field Balance-of-System (BOS) subsystems and site-specific design costs as compared to previous PV installations. These subsystems include site preparation, foundations, support structures, electrical writing, grounding, lightning protection, electromagnetic interference considerations, and controls. To reduce these BOS and design costs, standardized modular (building-block) designs for flat-panel and concentrator array fields have been developed that are fully integrated and optimized for lowest life-cycle costs. Using drawings and specifications now available, these building-block designs can be used in multiples to install various size array fields. The developed designs are immediately applicable (1982) and reduce the array-field BOS costs to a fraction of previous costs.

  11. Flat-panel electronic displays: a triumph of physics, chemistry and engineering.

    Science.gov (United States)

    Hilsum, Cyril

    2010-03-13

    This paper describes the history and science behind the development of modern flat-panel displays, and assesses future trends. Electronic displays are an important feature of modern life. For many years the cathode ray tube, an engineering marvel, was universal, but its shape was cumbersome and its operating voltage too high. The need for a flat-panel display, working at a low voltage, became imperative, and much research has been applied to this need. Any versatile flat-panel display will exploit an electro-optical effect, a transparent conductor and an addressing system to deliver data locally. The first need is to convert an electrical signal into a visible change. Two methods are available, the first giving emission of light, the second modulating ambient illumination. The most useful light-emitting media are semiconductors, historically exploiting III-V or II-VI compounds, but more recently organic or polymer semiconductors. Another possible effect uses gas plasma discharges. The modulating, or subtractive, effects that have been studied include liquid crystals, electrophoresis, electrowetting and electrochromism. A transparent conductor makes it possible to apply a voltage to an extended area while observing the results. The design is a compromise, since the free electrons that carry current also absorb light. The first materials used were metals, but some semiconductors, when heavily doped, give a better balance, with high transmission for a low resistance. Delivering data unambiguously to a million or so picture elements across the display area is no easy task. The preferred solution is an amorphous silicon thin-film transistor deposited at each cross-point in an X-Y matrix. Success in these endeavours has led to many applications for flat-panel displays, including television, flexible displays, electronic paper, electronic books and advertising signs.

  12. Attenuated phase-shift mask (PSM) blanks for flat panel display

    Science.gov (United States)

    Kageyama, Kagehiro; Mochizuki, Satoru; Yamakawa, Hiroyuki; Uchida, Shigeru

    2015-10-01

    The fine pattern exposure techniques are required for Flat Panel display applications as smart phone, tablet PC recently. The attenuated phase shift masks (PSM) are being used for ArF and KrF photomask lithography technique for high end pattern Semiconductor applications. We developed CrOx based large size PSM blanks that has good uniformity on optical characteristics for FPD applications. We report the basic optical characteristics and uniformity, stability data of large sized CrOx PSM blanks.

  13. Qualification test results for DOE solar photovoltaic flat panel procurement - PRDA 38

    Science.gov (United States)

    Griffith, J. S.

    1980-01-01

    Twelve types of prototypes modules for the DOE Photovoltaic Flat Panel Procurement (PRDA 38) were subjected to qualification tests at the Jet Propulsion Laboratory according to a new specification. Environmental exposures were carried out separately and included temperature cycling, humidity, wind simulation, and hail. The most serious problems discovered were reduced insulation resistance to ground and ground continuity of the metal frames, electrical degradation, erratic power readings, and delamination. The electrical and physical characteristics of the newly received modules are also given.

  14. Flat panel computed tomography of human ex vivo heart and bone specimens: initial experience

    Energy Technology Data Exchange (ETDEWEB)

    Nikolaou, Konstantin; Becker, Christoph R.; Reiser, Maximilian F. [Ludwig-Maximilians-University, Department of Clinical Radiology, Munich (Germany); Flohr, Thomas; Stierstorfer, Karl [CT Division, Siemens Medical Solutions, Forchheim (Germany)

    2005-02-01

    The aim of this technical investigation was the detailed description of a prototype flat panel detector computed tomography system (FPCT) and its initial evaluation in an ex vivo setting. The prototype FPCT scanner consists of a conventional radiographic flat panel detector, mounted on a multi-slice CT scanner gantry. Explanted human ex vivo heart and foot specimens were examined. Images were reformatted with various reconstruction algorithms and were evaluated for high-resolution anatomic information. For comparison purposes, the ex vivo specimens were also scanned with a conventional 16-detector-row CT scanner (Sensation 16, Siemens Medical Solutions, Forchheim, Germany). With the FPCT prototype used, a 1,024 x 768 resolution matrix can be obtained, resulting in an isotropic voxel size of 0.25 x 0.25 x 0.25 mm at the iso-center. Due to the high spatial resolution, very small structures such as trabecular bone or third-degree, distal branches of coronary arteries could be visualized. This first evaluation showed that flat panel detector systems can be used in a cone-beam computed tomography scanner and that very high spatial resolutions can be achieved. However, there are limitations for in vivo use due to constraints in low contrast resolution and slow scan speed. (orig.)

  15. Resolution requirements for monitor viewing of digital flat-panel detector radiographs: a contrast detail analysis

    International Nuclear Information System (INIS)

    Peer, Siegfried; Giacomuzzi, Salvatore M.; Peer, Regina; Gassner, Eva; Steingruber, Iris; Jaschke, Werner

    2003-01-01

    With the introduction of digital flat-panel detector systems into clinical practice, the still unresolved question of resolution requirements for picture archiving communication system (PACS) workstation monitors has gained new momentum. This contrast detail analysis was thus performed to define the differences in observer performance in the detection of small low-contrast objects on clinical 1K and 2K monitor workstations. Images of the CDRAD 2.0 phantom were acquired at varying exposures on an indirect-type digital flat-panel detector. Three observers evaluated a total of 15 images each with respect to the threshold contrast for each detail size. The numbers of correctly identified objects were determined for all image subsets. No significant difference in the correct detection ratio was detected among the observers; however, the difference between the two types of workstations (1K vs 2K monitors) despite less than 3% was significant at a 95% confidence level. Slight but statistically significant differences exist in the detection of low-contrast nodular details visualized on 1K- and 2K-monitor workstations. Further work is needed to see if this result holds true also for comparison of clinical flat-panel detector images and may, for example, exert an influence on the diagnostic accuracy of chest X-ray readings. (orig.)

  16. Portable low-cost flat panel detectors for real-time digital radiography

    Energy Technology Data Exchange (ETDEWEB)

    Iovea, Mihai; Neagu, Marian; Stefanescu, Bogdan; Mateiasi, Gabriela; Porosnicu, Ioana; Angheluta, Elena [Accent Pro 2000 S.R.L., Bucharest (Romania)

    2015-07-01

    The X-ray inspection is one of the most common used non-destructive testing methods in industry applications, but for the portable X-ray digital solution are not so many accessible, low-cost and versatile detection devices. The efficiency of a non-destructive X-ray portable device is represented by the quality of digital images, by its low acquisition time combined with a high resolution, in condition of low noise and at an affordable cost. The paper presents two X-ray portable imaging systems developed by us, suitable also for aerospace NDT applications, which are also very versatile for being easily adapted for other fields that requires mobile solutions. The first device described in the paper represent a portable large-size (210 mm X 550 mm) and high-resolution (27/54 microns) flat panel detector based on linear translation of a X-Ray TDI detector, destined for various components/parts real-time transmission measurements. The second system it is also a flat panel detectors, with a size of 510 mm X 610 mm, with the detector size from 0.2 mm until 1.5 mm, which can operate by applying the dual-energy method, very useful for discriminating materials by evaluating their Atomic effective number. The high resolution and low-cost of this flat-panels widens their applicability by covering large requirements, from identifying unwanted materials within a structure until detection of very thin cracks in complex components.

  17. Portable low-cost flat panel detectors for real-time digital radiography

    International Nuclear Information System (INIS)

    Iovea, Mihai; Neagu, Marian; Stefanescu, Bogdan; Mateiasi, Gabriela; Porosnicu, Ioana; Angheluta, Elena

    2015-01-01

    The X-ray inspection is one of the most common used non-destructive testing methods in industry applications, but for the portable X-ray digital solution are not so many accessible, low-cost and versatile detection devices. The efficiency of a non-destructive X-ray portable device is represented by the quality of digital images, by its low acquisition time combined with a high resolution, in condition of low noise and at an affordable cost. The paper presents two X-ray portable imaging systems developed by us, suitable also for aerospace NDT applications, which are also very versatile for being easily adapted for other fields that requires mobile solutions. The first device described in the paper represent a portable large-size (210 mm X 550 mm) and high-resolution (27/54 microns) flat panel detector based on linear translation of a X-Ray TDI detector, destined for various components/parts real-time transmission measurements. The second system it is also a flat panel detectors, with a size of 510 mm X 610 mm, with the detector size from 0.2 mm until 1.5 mm, which can operate by applying the dual-energy method, very useful for discriminating materials by evaluating their Atomic effective number. The high resolution and low-cost of this flat-panels widens their applicability by covering large requirements, from identifying unwanted materials within a structure until detection of very thin cracks in complex components.

  18. Evaluation of a flat panel digital radiographic system for low-dose portable imaging of neonates

    International Nuclear Information System (INIS)

    Samei, Ehsan; Hill, Jeanne G.; Frey, G. Donald; Southgate, W. Michael; Mah, Eugene; Delong, David

    2003-01-01

    The purpose of this study was to evaluate the clinical utility of an investigational flat-panel digital radiography system for low-dose portable neonatal imaging. Thirty image-pairs from neonatal intensive care unit patients were acquired with a commercial Computed Radiography system (Agfa, ADC 70), and with the investigational system (Varian, Paxscan 2520) at one-quarter of the exposure. The images were evaluated for conspicuity and localization of the endings of ancillary catheters and tubes in two observer performance experiments with three pediatric radiologists and three neonatologists serving as observers. The results indicated no statistically significant difference in diagnostic quality between the images from the investigational system and from CR. Given the investigational system's superior resolution and noise characteristics, observer results suggest that the high detective quantum efficiency of flat-panel digital radiography systems can be utilized to decrease the radiation dose/exposure to neonatal patients, although post-processing of the images remains to be optimized. The rapid availability of flat-panel images in portable imaging was found to be an added advantage for timely clinical decision-making

  19. High-performance flat-panel solar thermoelectric generators with high thermal concentration

    Science.gov (United States)

    Kraemer, Daniel; Poudel, Bed; Feng, Hsien-Ping; Caylor, J. Christopher; Yu, Bo; Yan, Xiao; Ma, Yi; Wang, Xiaowei; Wang, Dezhi; Muto, Andrew; McEnaney, Kenneth; Chiesa, Matteo; Ren, Zhifeng; Chen, Gang

    2011-07-01

    The conversion of sunlight into electricity has been dominated by photovoltaic and solar thermal power generation. Photovoltaic cells are deployed widely, mostly as flat panels, whereas solar thermal electricity generation relying on optical concentrators and mechanical heat engines is only seen in large-scale power plants. Here we demonstrate a promising flat-panel solar thermal to electric power conversion technology based on the Seebeck effect and high thermal concentration, thus enabling wider applications. The developed solar thermoelectric generators (STEGs) achieved a peak efficiency of 4.6% under AM1.5G (1 kW m-2) conditions. The efficiency is 7-8 times higher than the previously reported best value for a flat-panel STEG, and is enabled by the use of high-performance nanostructured thermoelectric materials and spectrally-selective solar absorbers in an innovative design that exploits high thermal concentration in an evacuated environment. Our work opens up a promising new approach which has the potential to achieve cost-effective conversion of solar energy into electricity.

  20. Tracking brachytherapy sources using emission imaging with one flat panel detector

    International Nuclear Information System (INIS)

    Song Haijun; Bowsher, James; Das, Shiva; Yin Fangfang

    2009-01-01

    This work proposes to use the radiation from brachytherapy sources to track their dwell positions in three-dimensional (3D) space. The prototype device uses a single flat panel detector and a BB tray. The BBs are arranged in a defined pattern. The shadow of the BBs on the flat panel is analyzed to derive the 3D coordinates of the illumination source, i.e., the dwell position of the brachytherapy source. A kilovoltage x-ray source located 3.3 m away was used to align the center BB with the center pixel on the flat panel detector. For a test plan of 11 dwell positions, with an Ir-192 high dose rate unit, one projection was taken for each dwell point, and locations of the BB shadows were manually identified on the projection images. The 3D coordinates for the 11 dwell positions were reconstructed based on two BBs. The distances between dwell points were compared with the expected values. The average difference was 0.07 cm with a standard deviation of 0.15 cm. With automated BB shadow recognition in the future, this technique possesses the potential of tracking the 3D trajectory and the dwell times of a brachytherapy source in real time, enabling real time source position verification.

  1. High-performance flat-panel solar thermoelectric generators with high thermal concentration.

    Science.gov (United States)

    Kraemer, Daniel; Poudel, Bed; Feng, Hsien-Ping; Caylor, J Christopher; Yu, Bo; Yan, Xiao; Ma, Yi; Wang, Xiaowei; Wang, Dezhi; Muto, Andrew; McEnaney, Kenneth; Chiesa, Matteo; Ren, Zhifeng; Chen, Gang

    2011-05-01

    The conversion of sunlight into electricity has been dominated by photovoltaic and solar thermal power generation. Photovoltaic cells are deployed widely, mostly as flat panels, whereas solar thermal electricity generation relying on optical concentrators and mechanical heat engines is only seen in large-scale power plants. Here we demonstrate a promising flat-panel solar thermal to electric power conversion technology based on the Seebeck effect and high thermal concentration, thus enabling wider applications. The developed solar thermoelectric generators (STEGs) achieved a peak efficiency of 4.6% under AM1.5G (1 kW m(-2)) conditions. The efficiency is 7-8 times higher than the previously reported best value for a flat-panel STEG, and is enabled by the use of high-performance nanostructured thermoelectric materials and spectrally-selective solar absorbers in an innovative design that exploits high thermal concentration in an evacuated environment. Our work opens up a promising new approach which has the potential to achieve cost-effective conversion of solar energy into electricity. © 2011 Macmillan Publishers Limited. All rights reserved

  2. Indirect flat-panel detector with avalanche gain: Fundamental feasibility investigation for SHARP-AMFPI (scintillator HARP active matrix flat panel imager)

    International Nuclear Information System (INIS)

    Zhao Wei; Li Dan; Reznik, Alla; Lui, B.J.M.; Hunt, D.C.; Rowlands, J.A.; Ohkawa, Yuji; Tanioka, Kenkichi

    2005-01-01

    An indirect flat-panel imager (FPI) with avalanche gain is being investigated for low-dose x-ray imaging. It is made by optically coupling a structured x-ray scintillator CsI(Tl) to an amorphous selenium (a-Se) avalanche photoconductor called HARP (high-gain avalanche rushing photoconductor). The final electronic image is read out using an active matrix array of thin film transistors (TFT). We call the proposed detector SHARP-AMFPI (scintillator HARP active matrix flat panel imager). The advantage of the SHARP-AMFPI is its programmable gain, which can be turned on during low dose fluoroscopy to overcome electronic noise, and turned off during high dose radiography to avoid pixel saturation. The purpose of this paper is to investigate the important design considerations for SHARP-AMFPI such as avalanche gain, which depends on both the thickness d Se and the applied electric field E Se of the HARP layer. To determine the optimal design parameter and operational conditions for HARP, we measured the E Se dependence of both avalanche gain and optical quantum efficiency of an 8 μm HARP layer. The results were used in a physical model of HARP as well as a linear cascaded model of the FPI to determine the following x-ray imaging properties in both the avalanche and nonavalanche modes as a function of E Se : (1) total gain (which is the product of avalanche gain and optical quantum efficiency); (2) linearity; (3) dynamic range; (4) gain nonuniformity resulting from thickness nonuniformity; and (5) effects of direct x-ray interaction in HARP. Our results showed that a HARP layer thickness of 8 μm can provide adequate avalanche gain and sufficient dynamic range for x-ray imaging applications to permit quantum limited operation over the range of exposures needed for radiography and fluoroscopy

  3. Designing, Modeling, Constructing, and Testing a Flat Panel Speaker and Sound Diffuser for a Simulator

    Science.gov (United States)

    Dillon, Christina

    2013-01-01

    The goal of this project was to design, model, build, and test a flat panel speaker and frame for a spherical dome structure being made into a simulator. The simulator will be a test bed for evaluating an immersive environment for human interfaces. This project focused on the loud speakers and a sound diffuser for the dome. The rest of the team worked on an Ambisonics 3D sound system, video projection system, and multi-direction treadmill to create the most realistic scene possible. The main programs utilized in this project, were Pro-E and COMSOL. Pro-E was used for creating detailed figures for the fabrication of a frame that held a flat panel loud speaker. The loud speaker was made from a thin sheet of Plexiglas and 4 acoustic exciters. COMSOL, a multiphysics finite analysis simulator, was used to model and evaluate all stages of the loud speaker, frame, and sound diffuser. Acoustical testing measurements were utilized to create polar plots from the working prototype which were then compared to the COMSOL simulations to select the optimal design for the dome. The final goal of the project was to install the flat panel loud speaker design in addition to a sound diffuser on to the wall of the dome. After running tests in COMSOL on various speaker configurations, including a warped Plexiglas version, the optimal speaker design included a flat piece of Plexiglas with a rounded frame to match the curvature of the dome. Eight of these loud speakers will be mounted into an inch and a half of high performance acoustic insulation, or Thinsulate, that will cover the inside of the dome. The following technical paper discusses these projects and explains the engineering processes used, knowledge gained, and the projected future goals of this project

  4. A semiempirical linear model of indirect, flat-panel x-ray detectors

    Energy Technology Data Exchange (ETDEWEB)

    Huang, Shih-Ying; Yang Kai; Abbey, Craig K.; Boone, John M. [Department of Biomedical Engineering, University of California, Davis, California, One Shields Avenue, Davis, California 95616 (United States) and Department of Radiology, University of California, Davis, Medical Center, 4860 Y Street, Ambulatory Care Center Suite 0505, Sacramento, California 95817 (United States); Department of Radiology, University of California, Davis, Medical Center, 4860 Y Street, Ambulatory Care Center Suite 0505, Sacramento, California 95817 (United States); Department of Psychological and Brain Sciences, University of California, Santa Barbara, California 92106 (United States); Department of Biomedical Engineering, University of California, Davis, California, One Shields Avenue, Davis, California 95616 (United States) and Department of Radiology, University of California, Davis, Medical Center, 4860 Y Street, Ambulatory Care Center Suite 3100, Sacramento, California 95817 (United States)

    2012-04-15

    Purpose: It is important to understand signal and noise transfer in the indirect, flat-panel x-ray detector when developing and optimizing imaging systems. For optimization where simulating images is necessary, this study introduces a semiempirical model to simulate projection images with user-defined x-ray fluence interaction. Methods: The signal and noise transfer in the indirect, flat-panel x-ray detectors is characterized by statistics consistent with energy-integration of x-ray photons. For an incident x-ray spectrum, x-ray photons are attenuated and absorbed in the x-ray scintillator to produce light photons, which are coupled to photodiodes for signal readout. The signal mean and variance are linearly related to the energy-integrated x-ray spectrum by empirically determined factors. With the known first- and second-order statistics, images can be simulated by incorporating multipixel signal statistics and the modulation transfer function of the imaging system. To estimate the semiempirical input to this model, 500 projection images (using an indirect, flat-panel x-ray detector in the breast CT system) were acquired with 50-100 kilovolt (kV) x-ray spectra filtered with 0.1-mm tin (Sn), 0.2-mm copper (Cu), 1.5-mm aluminum (Al), or 0.05-mm silver (Ag). The signal mean and variance of each detector element and the noise power spectra (NPS) were calculated and incorporated into this model for accuracy. Additionally, the modulation transfer function of the detector system was physically measured and incorporated in the image simulation steps. For validation purposes, simulated and measured projection images of air scans were compared using 40 kV/0.1-mm Sn, 65 kV/0.2-mm Cu, 85 kV/1.5-mm Al, and 95 kV/0.05-mm Ag. Results: The linear relationship between the measured signal statistics and the energy-integrated x-ray spectrum was confirmed and incorporated into the model. The signal mean and variance factors were linearly related to kV for each filter material (r

  5. A semiempirical linear model of indirect, flat-panel x-ray detectors

    International Nuclear Information System (INIS)

    Huang, Shih-Ying; Yang Kai; Abbey, Craig K.; Boone, John M.

    2012-01-01

    Purpose: It is important to understand signal and noise transfer in the indirect, flat-panel x-ray detector when developing and optimizing imaging systems. For optimization where simulating images is necessary, this study introduces a semiempirical model to simulate projection images with user-defined x-ray fluence interaction. Methods: The signal and noise transfer in the indirect, flat-panel x-ray detectors is characterized by statistics consistent with energy-integration of x-ray photons. For an incident x-ray spectrum, x-ray photons are attenuated and absorbed in the x-ray scintillator to produce light photons, which are coupled to photodiodes for signal readout. The signal mean and variance are linearly related to the energy-integrated x-ray spectrum by empirically determined factors. With the known first- and second-order statistics, images can be simulated by incorporating multipixel signal statistics and the modulation transfer function of the imaging system. To estimate the semiempirical input to this model, 500 projection images (using an indirect, flat-panel x-ray detector in the breast CT system) were acquired with 50-100 kilovolt (kV) x-ray spectra filtered with 0.1-mm tin (Sn), 0.2-mm copper (Cu), 1.5-mm aluminum (Al), or 0.05-mm silver (Ag). The signal mean and variance of each detector element and the noise power spectra (NPS) were calculated and incorporated into this model for accuracy. Additionally, the modulation transfer function of the detector system was physically measured and incorporated in the image simulation steps. For validation purposes, simulated and measured projection images of air scans were compared using 40 kV/0.1-mm Sn, 65 kV/0.2-mm Cu, 85 kV/1.5-mm Al, and 95 kV/0.05-mm Ag. Results: The linear relationship between the measured signal statistics and the energy-integrated x-ray spectrum was confirmed and incorporated into the model. The signal mean and variance factors were linearly related to kV for each filter material (r 2 of

  6. A semiempirical linear model of indirect, flat-panel x-ray detectors.

    Science.gov (United States)

    Huang, Shih-Ying; Yang, Kai; Abbey, Craig K; Boone, John M

    2012-04-01

    It is important to understand signal and noise transfer in the indirect, flat-panel x-ray detector when developing and optimizing imaging systems. For optimization where simulating images is necessary, this study introduces a semiempirical model to simulate projection images with user-defined x-ray fluence interaction. The signal and noise transfer in the indirect, flat-panel x-ray detectors is characterized by statistics consistent with energy-integration of x-ray photons. For an incident x-ray spectrum, x-ray photons are attenuated and absorbed in the x-ray scintillator to produce light photons, which are coupled to photodiodes for signal readout. The signal mean and variance are linearly related to the energy-integrated x-ray spectrum by empirically determined factors. With the known first- and second-order statistics, images can be simulated by incorporating multipixel signal statistics and the modulation transfer function of the imaging system. To estimate the semiempirical input to this model, 500 projection images (using an indirect, flat-panel x-ray detector in the breast CT system) were acquired with 50-100 kilovolt (kV) x-ray spectra filtered with 0.1-mm tin (Sn), 0.2-mm copper (Cu), 1.5-mm aluminum (Al), or 0.05-mm silver (Ag). The signal mean and variance of each detector element and the noise power spectra (NPS) were calculated and incorporated into this model for accuracy. Additionally, the modulation transfer function of the detector system was physically measured and incorporated in the image simulation steps. For validation purposes, simulated and measured projection images of air scans were compared using 40 kV∕0.1-mm Sn, 65 kV∕0.2-mm Cu, 85 kV∕1.5-mm Al, and 95 kV∕0.05-mm Ag. The linear relationship between the measured signal statistics and the energy-integrated x-ray spectrum was confirmed and incorporated into the model. The signal mean and variance factors were linearly related to kV for each filter material (r(2) of signal mean to k

  7. Visual and ocular effects from the use of flat-panel displays

    Directory of Open Access Journals (Sweden)

    Esteban Porcar

    2016-06-01

    Full Text Available AIM: To evaluate the prevalence of eye symptoms in a non-presbyopic population of video display unit (VDU users with flat-panel displays. METHODS: One hundred and sixteen VDU users with flat-panel display from an urban population participated in the study; their ages ranging from 20 to 34y. There were 60 females and 56 males. An eye examination to rule out the presence of significant uncorrected refractive errors, general binocular dysfunctions and eye conditions was carried out. In order to determine and quantify the type and nature of eye symptoms, participants were asked to answer written questionnaire and the results were grouped by gender, age and number of hours a day spent using a VDU. RESULTS: Seventy-two percent of participants reported eye symptoms related to VDU use. Eye symptoms from moderate-to-severe were found in 23% of participants. The main symptom was moderate-to-severe tired eyes (14%; followed by sensitivity to bright lights (12%, blurred vision at far distances (10%, eyestrain or dry eye or irritated or burning eyes (9%, difficulty in refocusing from one distance to another or headache (8% and blurred vision at near or intermediate distances (<4%. Eye symptoms were greater among females (P=0.005 and increased with VDU use, markedly above 6h spent using a VDU in a typical day (P=0.01. CONCLUSION: Significant eye symptoms relate to VDU use often occur and should not be underestimated. The increasing use of electronic devices with flat-panel display should prompt users to take appropriate measures to prevent or to relieve the eye symptoms arising from their use.

  8. Visual and ocular effects from the use of flat-panel displays.

    Science.gov (United States)

    Porcar, Esteban; Pons, Alvaro M; Lorente, Amalia

    2016-01-01

    To evaluate the prevalence of eye symptoms in a non-presbyopic population of video display unit (VDU) users with flat-panel displays. One hundred and sixteen VDU users with flat-panel display from an urban population participated in the study; their ages ranging from 20 to 34y. There were 60 females and 56 males. An eye examination to rule out the presence of significant uncorrected refractive errors, general binocular dysfunctions and eye conditions was carried out. In order to determine and quantify the type and nature of eye symptoms, participants were asked to answer written questionnaire and the results were grouped by gender, age and number of hours a day spent using a VDU. Seventy-two percent of participants reported eye symptoms related to VDU use. Eye symptoms from moderate-to-severe were found in 23% of participants. The main symptom was moderate-to-severe tired eyes (14%); followed by sensitivity to bright lights (12%), blurred vision at far distances (10%), eyestrain or dry eye or irritated or burning eyes (9%), difficulty in refocusing from one distance to another or headache (8%) and blurred vision at near or intermediate distances (<4%). Eye symptoms were greater among females (P=0.005) and increased with VDU use, markedly above 6h spent using a VDU in a typical day (P=0.01). Significant eye symptoms relate to VDU use often occur and should not be underestimated. The increasing use of electronic devices with flat-panel display should prompt users to take appropriate measures to prevent or to relieve the eye symptoms arising from their use.

  9. A camac based data acquisition system for flat-panel image array readout

    International Nuclear Information System (INIS)

    Morton, E.J.; Antonuk, L.E.; Berry, J.E.; Huang, W.; Mody, P.; Yorkston, J.; Longo, M.J.

    1993-01-01

    A readout system has been developed to facilitate the digitization and subsequent display of image data from two-dimensional, pixellated, flat-panel, amorphous silicon imaging arrays. These arrays have been designed specifically for medical x-ray imaging applications. The readout system is based on hardware and software developed for various experiments at CERN and Fermi National Accelerator Laboratory. Additional analog signal processing and digital control electronics were constructed specifically for this application. The authors report on the form of the resulting data acquisition system, discuss aspects of its performance, and consider the compromises which were involved in its design

  10. Flat panel detectors - closing the (digital) gap in chest and skeletal radiology

    International Nuclear Information System (INIS)

    Reiff, Kurt J.

    1999-01-01

    In the radiological department today the majority of all X-ray procedures on chest and skeletal radiography is performed with classical film-screen-systems. Using digital luminescence radiography (DLR or CR, which stands for Computed Radiography) as a technique has shown a way to replace this 100-year-old procedure of doing general radiography work by acquiring the X-rays digitally via phosphor screens, but this approach has faced criticism from lots of radiologists world wide and therefore has not been widely accepted except in the intensive care environment. A new technology is now rising based on the use of so called flat panel X-ray (FD) detectors. Semi-conducting material detects the X-rays in digital form directly and creates an instantaneous image for display, distribution and diagnosis. This ability combined with a large field of view and -- compared to existing methods -- excellent detective quantum efficiency represents a revolutionary step for chest and skeletal radiography and will put basic X-ray-work back into the focus of radiological solutions. This paper will explain the basic technology of flat panel detectors, possible system solutions based on this new technology, aspects of the user interface influencing the system utilization and versatility as well as the possibility to redefine the patient examination process for chest and skeletal radiography. Furthermore the author discusses limitations for the first released systems, upgrades for the installed base and possible scenarios for the future. e.g. fluoroscopy or angiography application

  11. Performance Characteristic of a CsI(Tl) Flat Panel Detector Radiography System

    International Nuclear Information System (INIS)

    Jeong, Hoi Woun; Min, Jung Hwan; Kim, Jung Min; Park, Min Seok; Lee, Gaung Young

    2012-01-01

    The purpose of this work was to evaluate an amorphous silicon cesium iodide based indirect flat-panel detector (FPD) in terms of their modulation transfer function (MTF), Wiener spectrum (WS, or noise power spectrum, NPS), and detective quantum efficiency (DQE). Measurements were made on flat-panel detector using the International Electrotechnical Commission (IEC) defined RQA3, RQA5, RQA7, and RQA9 radiographic technique. The MTFs of the systems were measured using an edge method. The WS(NPS) of the systems were determined for a range of exposure levels by two-dimensional (2D). Fourier analysis of uniformly exposed radiographs. The DQEs were assessed from the measured MTF, WS(NPS), exposure, and estimated ideal signal-to-noise ratios. Characteristic curve in the RQA3 showed difference in the characteristic curve from RQA5, RQA7, RQA9. MTFs were not differences according to x-ray beam quality. WS(NPS) was reduced with increasing dose, and RQA 3, RQA5, RQA7, RQA9 as the order is reduced. DQE represented the best in the 1mR, RQA 3, RQA5, RQA7, RQA9 decrease in the order. The physical imaging characteristics of FPD may also differ from input beam quality. This study gives an initial motivation that the physical imaging characteristics of FPD is an important issue for the right use of digital radiography system.

  12. Performance Characteristic of a CsI(Tl) Flat Panel Detector Radiography System

    Energy Technology Data Exchange (ETDEWEB)

    Jeong, Hoi Woun [Dept. of Radiological Science, Baekseok Culture University, Seoul (Korea, Republic of); Min, Jung Hwan [Dept. of Radiological Technology, Shingu University, Seongnam (Korea, Republic of); Kim, Jung Min [Dept. of Radiological Science, Korea University, Health Science College, Seoul (Korea, Republic of); Park, Min Seok [Korea Institue of Radiological and Medical Sicences, Research Institute of Radiologycal and Medical Sciences, Seoul (Korea, Republic of); Lee, Gaung Young [National Institute of Food and Drug Safety Evaluation, Seoul (Korea, Republic of)

    2012-06-15

    The purpose of this work was to evaluate an amorphous silicon cesium iodide based indirect flat-panel detector (FPD) in terms of their modulation transfer function (MTF), Wiener spectrum (WS, or noise power spectrum, NPS), and detective quantum efficiency (DQE). Measurements were made on flat-panel detector using the International Electrotechnical Commission (IEC) defined RQA3, RQA5, RQA7, and RQA9 radiographic technique. The MTFs of the systems were measured using an edge method. The WS(NPS) of the systems were determined for a range of exposure levels by two-dimensional (2D). Fourier analysis of uniformly exposed radiographs. The DQEs were assessed from the measured MTF, WS(NPS), exposure, and estimated ideal signal-to-noise ratios. Characteristic curve in the RQA3 showed difference in the characteristic curve from RQA5, RQA7, RQA9. MTFs were not differences according to x-ray beam quality. WS(NPS) was reduced with increasing dose, and RQA 3, RQA5, RQA7, RQA9 as the order is reduced. DQE represented the best in the 1mR, RQA 3, RQA5, RQA7, RQA9 decrease in the order. The physical imaging characteristics of FPD may also differ from input beam quality. This study gives an initial motivation that the physical imaging characteristics of FPD is an important issue for the right use of digital radiography system.

  13. Comparison of dose and image quality of a Flat-panel detector and an image intensifier

    International Nuclear Information System (INIS)

    Lazzaro, M.; Friedrich, B.Q.; Luz, R.M. da; Silva, A.M.M. da

    2016-01-01

    With the development of new technologies, have emerged new conversion methods of X-ray image, such as flat panel detectors. The aim of this work is the comparison of entrance surface air kerma (ESAK) and image quality between an image intensifier type of detector (A) and a flat panel (B). The ESAK was obtained by placing a ionization chamber under PMMA simulators of 10, 20 and 30 cm and the image quality was obtained by using the TOR "1"8FG simulator. The ESAK to the equipment A is higher when compared to the equipment B. The high contrast resolution is better for the equipment A for all thicknesses of simulators. The equipment A has low contrast resolution with a better viewing threshold for thicknesses of 10 and 20 cm, and a worse performance for 30 cm. It is concluded that the equipment B has ESAK smaller and despite having lower resolution, in almost all cases, have appropriate image quality for diagnosis. (author)

  14. Acoustic Analysis Method for Flat Panel Speaker Driven by Giant Magnetostrictive-Material-Based Exciter(Linear Motor concerning Daily Life)

    OpenAIRE

    兪, 炳振; 平田, 勝弘; 大西, 敦郎; Byungjin, YOO; Katsuhiro, HIRATA; Atsurou, OONISHI; 大阪大学; 大阪大学; 大阪大学

    2011-01-01

    This paper presents a coupled analysis method of electromagnetic-structural-acoustic fields for flat panel speaker driven by giant magnetostrictive material (GMM) based exciter designed by using the finite element method (FEM). The acoustic field creation of the flat panel speaker driven by GMM exciter relies on the vibration of flat panel caused by magnetostrictive phenomenon of GMM when a magnetic field is applied. In this case, to predict the sound pressure level (SPL) at audio frequency r...

  15. An asynchronous, pipelined, electronic acquisition system for Active Matrix Flat-Panel Imagers (AMFPIs)

    CERN Document Server

    Huang, W; Berry, J; Maolinbay, M; Martelli, C; Mody, P; Nassif, S; Yeakey, M

    1999-01-01

    The development of a full-custom electronic acquisition system designed for readout of large-area active matrix flat-panel imaging arrays is reported. The arrays, which comprise two-dimensional matrices of pixels utilizing amorphous silicon thin-film transistors, are themselves under development for a wide variety of X-ray imaging applications. The acquisition system was specifically designed to facilitate detailed, quantitative investigations of the properties of these novel imaging arrays and contains significant enhancements compared to a previously developed acquisition system. These enhancements include pipelined preamplifier circuits to allow faster readout speed, expanded addressing capabilities allowing a maximum of 4096 array data lines, and on-board summing of image frames. The values of many acquisition system parameters, including timings and voltages, may be specified and downloaded from a host computer. Once acquisition is enabled, the system operates asynchronously of its host computer. The sys...

  16. Feasibility study of flexible flat-panel X-ray detectors for digital radiography

    International Nuclear Information System (INIS)

    Joe, Ok La; Yun, Seung Man; Kim, Ho Kyung

    2010-01-01

    Flexible flat-panel detectors (FPDs), which utilize both organic photodiode (OPD) and organic thin-film transistor (OTFT) technologies, are recently concerned in digital radiography. The flexible FPD has several potential advantages, such as high accessibility to patient, avoidance of geometrical burr due to the oblique angle incidence of X-ray, great reduction in manufacturing cost due to jet-printing. At once, The OPD/OTFT arrays were fabricated by jet-printing techniques, mechanical robustness due to plastic substrates, and so on. In this study, we have investigated the feasibility of flexible FPD by comparing theoretical detective quantum efficiency (DQE) with that of the conventional amorphous silicon-based FPD. We chose copper phthalocyanine-fullerene (CuPc-C60) organic materials for the construction of the flexible FPD. DQE was calculated by the linear-systems transfer theory

  17. Progress toward clinical implementation of the first flat-panel amorphous silicon imager

    International Nuclear Information System (INIS)

    Antonuk, Larry E.; El-Mohri, Youcef; Weidong, Huang; Sandler, Howard; Siewerdsen, Jeffrey H.; Yorkston, John

    1995-01-01

    Purpose: Approximately 7 years after the development of the general concept, megavoltage imagers based on thin-film, flat-panel electronics will likely enter routine clinical use within the next few years. In this paper, current capabilities and anticipated development of this imaging technology as pertains to clinical use will be presented. The results of the first use of this technology with an early prototype imager in a clinical setting are reported. The development of a more advanced clinical prototype imager designed for routine clinical use is described and the clinically-relevant capabilities, advantages, and limitations of this device are described. Materials and Methods: Flat-panel amorphous silicon imagers consist of an imaging array, an x-ray converter, external data acquisition electronics, along with appropriate software and a host workstation. The array consists of a two-dimensional grid of imaging pixels with each pixel consisting of a transistor coupled to a photodiode. An initial study of patient imaging has been performed with an early prototype imager which incorporates a 512x560 array with 450 μm pixels giving an imaging surface of 23x25 cm 2 . Portal images acquired with this prototype imager and with film under similar geometric and irradiation conditions were acquired and compared. In addition, a clinical prototype imager based upon a 26x26 cm 2 array with 508 μm pixels (512x512 pixels) is under development. This prototype incorporates advanced analog and digital external electronics which will improve imaging performance thereby increasing clinical utility of the device. The imagers are interfaced to the operation of a treatment machine so as to allow both radiographic and fluoroscopic operation. Results: The image quality is limited by the presence of pixel and line defects in the array and by the presence of correlated and uncorrelated noise sources in the acquisition system. Nevertheless, the contrast and spatial resolution offered by

  18. Critical issues in enhancing brightness in thin film phosphors for flat-panel display applications

    International Nuclear Information System (INIS)

    Singh, R.K.; Chen, Z.; Kumar, D.; Cho, K.; Ollinger, M.

    2002-01-01

    Thin film phosphors have potential applications in field emission flat-panel displays. However, they are limited by the lower cathodoluminescent brightness in comparison to phosphor powders. In this paper, we have investigated the critical parameters that need to be optimized to increase the brightness of phosphor thin films. Specifically, we studied the role of surface roughness and optical properties of the substrate on the brightness of the phosphor films. Thin Y 2 O 3 :Eu phosphor films were deposited on various substrates (lanthanum aluminate, quartz, sapphire, and silicon) with thicknesses varying from 50 to 500 nm. A model that accounts for diffuse and specular or scattering effects has been developed to understand the effects of the microstructure on the emission characteristics of the cathodoluminescent films. The results from the model show that both the optical properties of the substrate and the surface roughness of the films play a critical role in controlling the brightness of laser deposited phosphor films

  19. Modelling of scintillator based flat-panel detectors with Monte-Carlo simulations

    International Nuclear Information System (INIS)

    Reims, N; Sukowski, F; Uhlmann, N

    2011-01-01

    Scintillator based flat panel detectors are state of the art in the field of industrial X-ray imaging applications. Choosing the proper system and setup parameters for the vast range of different applications can be a time consuming task, especially when developing new detector systems. Since the system behaviour cannot always be foreseen easily, Monte-Carlo (MC) simulations are keys to gain further knowledge of system components and their behaviour for different imaging conditions. In this work we used two Monte-Carlo based models to examine an indirect converting flat panel detector, specifically the Hamamatsu C9312SK. We focused on the signal generation in the scintillation layer and its influence on the spatial resolution of the whole system. The models differ significantly in their level of complexity. The first model gives a global description of the detector based on different parameters characterizing the spatial resolution. With relatively small effort a simulation model can be developed which equates the real detector regarding signal transfer. The second model allows a more detailed insight of the system. It is based on the well established cascade theory, i.e. describing the detector as a cascade of elemental gain and scattering stages, which represent the built in components and their signal transfer behaviour. In comparison to the first model the influence of single components especially the important light spread behaviour in the scintillator can be analysed in a more differentiated way. Although the implementation of the second model is more time consuming both models have in common that a relatively small amount of system manufacturer parameters are needed. The results of both models were in good agreement with the measured parameters of the real system.

  20. Technical trends of large-size photomasks for flat panel displays

    Science.gov (United States)

    Yoshida, Koichiro

    2017-06-01

    Currently, flat panel displays (FPDs) are one of the main parts for information technology devices and sets. From 1990's to 2000's, liquid crystal displays (LCDs) and plasma displays had been mainstream FPDs. In the middle of 2000's, demand of plasma displays declined and organic light emitting diodes (OLEDs) newly came into FPD market. And today, major technology of FPDs are LCDs and OLEDs. Especially for mobile devices, the penetration of OLEDs is remarkable. In FPDs panel production, photolithography is the key technology as same as LSI. Photomasks for FPDs are used not only as original master of circuit pattern, but also as a tool to form other functional structures of FPDs. Photomasks for FPDs are called as "Large Size Photomasks(LSPMs)", since the remarkable feature is " Size" which reaches over 1- meter square and over 100kg. In this report, we discuss three LSPMs technical topics with FPDs technical transition and trend. The first topics is upsizing of LSPMs, the second is the challenge for higher resolution patterning, and the last is "Multi-Tone Mask" for "Half -Tone Exposure".

  1. Compact flat-panel gas-gap heat switch operating at 295 K

    Science.gov (United States)

    Krielaart, M. A. R.; Vermeer, C. H.; Vanapalli, S.

    2015-11-01

    Heat switches are devices that can change from a thermally conducting (on-) state to an insulating (off-) state whenever the need arises. They enable adaptive thermal management strategies in which cooling rates are altered either spatially or temporally, leading to a substantial reduction in the energy and mass budget of a large range of systems. State-of-the-art heat switches are only rarely employed in thermal system architectures, since they are rather bulky and have a limited thermal performance (expressed as the heat transfer ratio between the on- and off-state heat conductance). Using selective laser melting additive manufacturing technology, also known as 3D printing, we developed a compact flat-panel gas-gap heat switch that offers superior thermal performance, is simpler and more economic to produce and assemble, contains no moving parts, and is more reliable because it lacks welded joints. The manufactured rectangular panel heat switch has frontal device dimensions of 10 cm by 10 cm, thickness of 3.2 mm and weighs just 121 g. An off heat conductance of 0.2 W/K and on-off heat conductance ratio of 38 is observed at 295 K.

  2. Establishment of action levels for quality control of IMRT flat panel: experience with the algorithm iGRiMLO

    International Nuclear Information System (INIS)

    Gonzalez, V.; Dolores, VV. de los; Pastor, V.; Martinez, J.; Gimeno, J.; Guardino, C.; Crispin, V.

    2011-01-01

    Algorithm has been used at our institution iGRiMLO scheduled for individual verification of treatment plans for intensity modulated radiotherapy (IMRT) step and shoot through portal dosimetry pretreatment of non-transmission, triggering the plan directly to a portal imaging device (EPID) of an amorphous silicon flat panel.

  3. Initial experiences in clinical application of the THORAX-FD: flat-panel detector radiography in thoracic diagnosis

    International Nuclear Information System (INIS)

    Herrmann, K.A.; Staebler, A.; Bonel, H.; Kulinna, C.; Holzknecht, N.; Reiser, M.F.; Geiger, B.; Boehm, S.; Maschke, M.

    2000-01-01

    The flat-panel detector closes the gap between radiography and the digital diagnostics equipment currently in use. In addition to the dose reduction that can be expected, the availability of diagnostic information in digital form enables the user to optimize the clinical workflow and to network radiography directly with a digital archiving and communication system. (orig.)

  4. Clinical evaluation of digital angiographic system equipped with the Safire' flat-panel detector of a direct conversion type

    International Nuclear Information System (INIS)

    Miura, Yoshiaki; Miura, Yusuke; Goto, Keiichi

    2003-01-01

    This report presents a report on clinical evaluation of our newly developed flat-panel X-ray detector of a direct conversion type, designed to provide images of a resolution higher than, or at least equal to, that ensured by X-ray photographic films, in clinical digital X-ray cinematography. This new detector was named 'Safire' the acronym of 'Shimadzu advanced flat imaging receptor', emphasizing its high technological level, such as the capability to ensure high quality of images. The clinical evaluation of Shimadzu DIGITEX Premier digital angiography system, equipped with this new flat-panel X-ray detector of a direct conversion type, has been started in March, 2003, at the Kokura Memorial Hospital in Kyushu, Japan. (author)

  5. Source strength verification and quality assurance of preloaded brachytherapy needles using a CMOS flat panel detector

    Energy Technology Data Exchange (ETDEWEB)

    Golshan, Maryam, E-mail: maryam.golshan@bccancer.bc.ca [Department of Physics, University of British Columbia, Vancouver, British Columbia V6T1Z1, Canada and Department of Medical Physics, Vancouver Center, British Columbia Cancer Agency, Vancouver, British Columbia V5Z 4E6 (Canada); Spadinger, Ingrid [Department of Medical Physics, Vancouver Center, British Columbia Cancer Agency, Vancouver, British Columbia V5Z 4E6 (Canada); Chng, Nick [Department of Medical Physics, Center for the North, British Columbia Cancer Agency, Prince George, British Columbia V2M 7E9 (Canada)

    2016-06-15

    Purpose: Current methods of low dose rate brachytherapy source strength verification for sources preloaded into needles consist of either assaying a small number of seeds from a separate sample belonging to the same lot used to load the needles or performing batch assays of a subset of the preloaded seed trains. Both of these methods are cumbersome and have the limitations inherent to sampling. The purpose of this work was to investigate an alternative approach that uses an image-based, autoradiographic system capable of the rapid and complete assay of all sources without compromising sterility. Methods: The system consists of a flat panel image detector, an autoclavable needle holder, and software to analyze the detected signals. The needle holder was designed to maintain a fixed vertical spacing between the needles and the image detector, and to collimate the emissions from each seed. It also provides a sterile barrier between the needles and the imager. The image detector has a sufficiently large image capture area to allow several needles to be analyzed simultaneously.Several tests were performed to assess the accuracy and reproducibility of source strengths obtained using this system. Three different seed models (Oncura 6711 and 9011 {sup 125}I seeds, and IsoAid Advantage {sup 103}Pd seeds) were used in the evaluations. Seeds were loaded into trains with at least 1 cm spacing. Results: Using our system, it was possible to obtain linear calibration curves with coverage factor k = 1 prediction intervals of less than ±2% near the centre of their range for the three source models. The uncertainty budget calculated from a combination of type A and type B estimates of potential sources of error was somewhat larger, yielding (k = 1) combined uncertainties for individual seed readings of 6.2% for {sup 125}I 6711 seeds, 4.7% for {sup 125}I 9011 seeds, and 11.0% for Advantage {sup 103}Pd seeds. Conclusions: This study showed that a flat panel detector dosimetry system

  6. On site evaluation of three flat panel detectors for digital radiography

    International Nuclear Information System (INIS)

    Borasi, Giovanni; Nitrosi, Andrea; Ferrari, Paolo; Tassoni, Davide

    2003-01-01

    During a tender we evaluated the image performance of three commercially available active matrix flat panel imagers (AMFPI) for general radiography, one based on direct detection method (Se photoconductor) the other two on indirect detection method (CsI phosphor). Basic image quality parameters (MTF, NNPS, DQE) were evaluated with particular attention to dose and energy dependence. As it is known, presampling modulation transfer function (MTF) of selenium based detector is very high (at 70 kV, 2 cycles/mm, 2.5 μGy, about 0.80). Indirect detection panels exhibit a comparable (lower) resolution (at 70 kV, 2 cycles/mm, 2.5 μGy, MTF is about 0.34 for both the systems analyzed) and a more pronounced energy and dose dependence could also be noted in one of them. As a consequence of the very high resolution, the normalized noise power spectrum (NNPS) of the direct system is substantially flat, very similar to a white noise. Considering that the sensitive layer of all detectors is the same (0.5 mm), the relatively higher NNPS values are related to selenium absorption properties (lower Z respect to CsI:Tl) and detector inherent noise. NNPSs of the other systems, at low frequencies, are comparable but the frequency dependence is significantly different. At 70 kV, 2.5 μGy, 0.5 cycles/mm detective quantum efficiency (DQE) is about 0.35 for the direct detection system, and about the same (0.6) for the indirect ones. The combined effect of additive and multiplicative noise components makes DQE dependence on dose not monotonic. DQE present a maximum for an intermediate exposure. This complex behavior may be useful to characterize the systems in terms of the monodimensional integral over the frequency of DQE (IDQE). Both visual contrast-detail experiment and the direct evaluation of the signal-to-noise ratio confirmed, at least in a qualitative way, the system performances predicted by IDQE

  7. Investigation of the dosimetric properties of an a-Si flat panel epid

    International Nuclear Information System (INIS)

    Fielding, A.L.; Jahangir, S.T.

    2004-01-01

    Full text: Electronic portal imaging devices (EPIDs) are primarily used as an electronic replacement for film to verify the set-up of radiotherapy patients based on imaged anatomy. There has recently been much interest in the use of amorphous silicon (a-Si) flat panel EPIDs for dosimetric verification in radiotherapy. The work presented here has been carried out to determine their suitability for dosimetric applications by investigating some of the basic response characteristics and the implications these might have. The measurements reported in this paper were performed using 6-MV photon beams from an Elekta Precise linear accelerator fitted with Elekta iViewGT amorphous silicon flat panel EPIDs. Measurements were performed to investigate the response of the EPID as a function of exposure and field size. Similar measurements were made with an ionisation chamber for comparison. Further measurements were carried out to investigate the response of the EPID to multiple low dose exposures (e.g. 5x2 MU) such as might be encountered in Intensity Modulated Radiotherapy (IMRT). This was compared with the response to a single high dose exposure (e.g. 10 MU) and repeated for a range of exposures. The results show the response of the EPID, to a good approximation, to be linear with dose over the range of 1 -200 MU. However, 'under-responses' in the EPID of up to 5% were seen at the lowest exposures. For multiple low dose segments the sum of the EPID responses was found to be less than the response to the same total exposure in a single large segment. This effect reduces with increase in the magnitude of the low dose segments. The variation in EPID response with field size was found to be greater than that indicated by the ionisation chamber. The results show that the a-Si detector responds to dose, to a good approximation, in a linear manner. The EPID under-response at low doses is thought to be related to the so called ghosting effect. Each image frame has a residual

  8. Impact and Penetration of Thin Aluminum 2024 Flat Panels at Oblique Angles of Incidence

    Science.gov (United States)

    Ruggeri, Charles R.; Revilock, Duane M.; Pereira, J. Michael; Emmerling, William; Queitzsch, Gilbert K., Jr.

    2015-01-01

    under more extreme conditions, using a projectile with a more complex shape and sharp contacts, impacting flat panels at oblique angles of incidence.

  9. Implementation of a program of quality assurance of image in an imaging system of flat panel portal; Puesta en marcha de un programa de garantia de calidad de imagen en un sistema de imagen portal de panel plano

    Energy Technology Data Exchange (ETDEWEB)

    Gomez Barrado, A.; Sanchez Jimenez, E.; Benitez, J. A.; Sanchez-Reyes, A.

    2013-07-01

    (IGRT) image-guided radiation therapy is the one in which images are used to locate the area of treatment. Modern irradiation systems are equipped with different modalities for obtaining images, such as flat panel systems, systems conebeam, tomoimagen, etc. This paper describes the start-up and the experience of a quality assurance program based on a flat panel portal Imaging System. (Author)

  10. Solid-state, flat-panel, digital radiography detectors and their physical imaging characteristics

    Energy Technology Data Exchange (ETDEWEB)

    Cowen, A.R. [LXi Research, Academic Unit of Medical Physics, University of Leeds, West Yorkshire (United Kingdom)], E-mail: a.r.cowen@leeds.ac.uk; Kengyelics, S.M.; Davies, A.G. [LXi Research, Academic Unit of Medical Physics, University of Leeds, West Yorkshire (United Kingdom)

    2008-05-15

    Solid-state, digital radiography (DR) detectors, designed specifically for standard projection radiography, emerged just before the turn of the millennium. This new generation of digital image detector comprises a thin layer of x-ray absorptive material combined with an electronic active matrix array fabricated in a thin film of hydrogenated amorphous silicon (a-Si:H). DR detectors can offer both efficient (low-dose) x-ray image acquisition plus on-line readout of the latent image as electronic data. To date, solid-state, flat-panel, DR detectors have come in two principal designs, the indirect-conversion (x-ray scintillator-based) and the direct-conversion (x-ray photoconductor-based) types. This review describes the underlying principles and enabling technologies exploited by these designs of detector, and evaluates their physical imaging characteristics, comparing performance both against each other and computed radiography (CR). In standard projection radiography indirect conversion DR detectors currently offer superior physical image quality and dose efficiency compared with direct conversion DR and modern point-scan CR. These conclusions have been confirmed in the findings of clinical evaluations of DR detectors. Future trends in solid-state DR detector technologies are also briefly considered. Salient innovations include WiFi-enabled, portable DR detectors, improvements in x-ray absorber layers and developments in alternative electronic media to a-Si:H.

  11. An asynchronous, pipelined, electronic acquisition system for Active Matrix Flat-Panel Imagers (AMFPIs)

    Energy Technology Data Exchange (ETDEWEB)

    Huang, W.; Antonuk, L.E. E-mail: antonuk@umich.edu; Berry, J.; Maolinbay, M.; Martelli, C.; Mody, P.; Nassif, S.; Yeakey, M

    1999-07-11

    The development of a full-custom electronic acquisition system designed for readout of large-area active matrix flat-panel imaging arrays is reported. The arrays, which comprise two-dimensional matrices of pixels utilizing amorphous silicon thin-film transistors, are themselves under development for a wide variety of X-ray imaging applications. The acquisition system was specifically designed to facilitate detailed, quantitative investigations of the properties of these novel imaging arrays and contains significant enhancements compared to a previously developed acquisition system. These enhancements include pipelined preamplifier circuits to allow faster readout speed, expanded addressing capabilities allowing a maximum of 4096 array data lines, and on-board summing of image frames. The values of many acquisition system parameters, including timings and voltages, may be specified and downloaded from a host computer. Once acquisition is enabled, the system operates asynchronously of its host computer. The system allows image capture in both radiographic mode (corresponding to the capture of individual X-ray images), and fluoroscopic mode (corresponding to the capture of a continual series of X-ray images). A detailed description of the system architecture and the underlying motivations for the design is reported in this paper. (author)

  12. Potential Applications of Flat-Panel Volumetric CT in Morphologic, Functional Small Animal Imaging

    Directory of Open Access Journals (Sweden)

    Susanne Greschus

    2005-08-01

    Full Text Available Noninvasive radiologic imaging has recently gained considerable interest in basic, preclinical research for monitoring disease progression, therapeutic efficacy. In this report, we introduce flat-panel volumetric computed tomography (fpVCT as a powerful new tool for noninvasive imaging of different organ systems in preclinical research. The three-dimensional visualization that is achieved by isotropic high-resolution datasets is illustrated for the skeleton, chest, abdominal organs, brain of mice. The high image quality of chest scans enables the visualization of small lung nodules in an orthotopic lung cancer model, the reliable imaging of therapy side effects such as lung fibrosis. Using contrast-enhanced scans, fpVCT displayed the vascular trees of the brain, liver, kidney down to the subsegmental level. Functional application of fpVCT in dynamic contrast-enhanced scans of the rat brain delivered physiologically reliable data of perfusion, tissue blood volume. Beyond scanning of small animal models as demonstrated here, fpVCT provides the ability to image animals up to the size of primates.

  13. Dynamic chest radiography: flat-panel detector (FPD) based functional X-ray imaging.

    Science.gov (United States)

    Tanaka, Rie

    2016-07-01

    Dynamic chest radiography is a flat-panel detector (FPD)-based functional X-ray imaging, which is performed as an additional examination in chest radiography. The large field of view (FOV) of FPDs permits real-time observation of the entire lungs and simultaneous right-and-left evaluation of diaphragm kinetics. Most importantly, dynamic chest radiography provides pulmonary ventilation and circulation findings as slight changes in pixel value even without the use of contrast media; the interpretation is challenging and crucial for a better understanding of pulmonary function. The basic concept was proposed in the 1980s; however, it was not realized until the 2010s because of technical limitations. Dynamic FPDs and advanced digital image processing played a key role for clinical application of dynamic chest radiography. Pulmonary ventilation and circulation can be quantified and visualized for the diagnosis of pulmonary diseases. Dynamic chest radiography can be deployed as a simple and rapid means of functional imaging in both routine and emergency medicine. Here, we focus on the evaluation of pulmonary ventilation and circulation. This review article describes the basic mechanism of imaging findings according to pulmonary/circulation physiology, followed by imaging procedures, analysis method, and diagnostic performance of dynamic chest radiography.

  14. A performance comparison of direct- and indirect-detection flat-panel imagers

    CERN Document Server

    Partridge, M; Müller, L

    2002-01-01

    A comparison of the performance of a direct- and an indirect-detection amorphous silicon flat-panel X-ray imager is presented for a 6 MV beam. Experimental measurements of the noise characteristics, image lag, spectral response, spatial resolution and quantum efficiency are described, compared and discussed. The two systems are comprised of 512x512 pixel, 400 mu m pitch, arrays of a-Si:H p-i-n photodiodes and thin-film transistors. In the direct-detection system, X-rays interact to produce electron/hole pairs directly in the silicon photodiodes. For the indirect-detection system, a phosphor screen converts energy from the incident X-rays into visible light, which is then detected by the photodiodes. Both systems are shown to be quantum noise limited, with the total electronic noise in the detector 10-15 times smaller than the Poisson noise level in detected signal. The measured lag for both systems is 1.0+-0.1% or less in the first frame with subsequent signals decaying exponentially with frame read-out, with...

  15. Beyond the limits of present active matrix flat-panel imagers (AMFPIs) for diagnostic radiology

    Science.gov (United States)

    Antonuk, Larry E.; El-Mohri, Youcef; Jee, Kyung-Wook; Maolinbay, Manat; Nassif, Samer C.; Rong, Xiujiang; Siewerdsen, Jeffrey H.; Zhao, Qihua; Street, Robert A.

    1999-05-01

    A theoretical cascaded systems analysis of the performance limits of x-ray imagers based on thin-film, active matrix flat-panel technology is presented. This analysis specifically focuses upon an examination of the functional dependence of the detective quantum efficiency on exposure. While the DQE of AMFPI systems is relatively high at the large exposure levels associated with radiographic x-ray imaging, there is a significant decline in DQE with decreasing exposure over the medium and lower end of the exposure range associated with fluoroscopic imaging. This fall-off in DQE originates from the relatively large size of the additive noise of AMFPI systems compared to their overall system gain. Therefore, strategies to diminish additive noise and increase system gain should significantly improve performance. Potential strategies for noise reduction include the use of charge compensation lines while strategies for gain enhancement include continuous photodiodes, pixel amplification structures, or higher gain converters. The effect of the implementation of such strategies is examined for a variety for hypothetical imager configurations. Through the modeling of these configurations, such enhancements are shown to hold the potential of making low frequency DQE response large and essentially independent of exposure while greatly reducing the fall-off in DQE at higher spatial frequencies.

  16. Contrast-detail analysis of three flat panel detectors for digital radiography

    International Nuclear Information System (INIS)

    Borasi, Giovanni; Samei, Ehsan; Bertolini, Marco; Nitrosi, Andrea; Tassoni, Davide

    2006-01-01

    In this paper we performed a contrast detail analysis of three commercially available flat panel detectors, two based on the indirect detection mechanism (GE Revolution XQ/i, system A, and Trixell/Philips Pixium 4600, system B) and one based on the direct detection mechanism (Hologic DirectRay DR 1000, system C). The experiment was conducted using standard x-ray radiation quality and a widely used contrast-detail phantom. Images were evaluated using a four alternative forced choice paradigm on a diagnostic-quality softcopy monitor. At the low and intermediate exposures, systems A and B gave equivalent performances. At the high dose levels, system A performed better than system B in the entire range of target sizes, even though the pixel size of system A was about 40% larger than that of system B. At all the dose levels, the performances of the system C (direct system) were lower than those of system A and B (indirect systems). Theoretical analyses based on the Perception Statistical Model gave similar predicted SNR T values corresponding to an observer efficiency of about 0.08 for systems A and B and 0.05 for system C

  17. Practical expressions describing detective quantum efficiency in flat-panel detectors

    Science.gov (United States)

    Kim, H. K.

    2011-11-01

    In radiology, image quality excellence is a balance between system performance and patient dose, hence x-ray systems must be designed to ensure the maximum image quality is obtained for the lowest consistent dose. The concept of detective quantum efficiency (DQE) is widely used to quantify, understand, measure, and predict the performance of x-ray detectors and imaging systems. Cascaded linear-systems theory can be used to estimate DQE based on the system design parameters and this theoretical DQE can be utilized for determining the impact of various physical processes, such as secondary quantum sinks, noise aliasing, reabsorption noise, and others. However, the prediction of DQE usually requires tremendous efforts to determine each parameter consisting of the cascaded linear-systems model. In this paper, practical DQE formalisms assessing both the photoconductor- and scintillator-based flat-panel detectors under quantum-noise-limited operation are described. The developed formalisms are experimentally validated and discussed for their limits. The formalisms described in this paper would be helpful for the rapid prediction of the DQE performances of developing systems as well as the optimal design of systems.

  18. Ultra-high resolution flat-panel volume CT: fundamental principles, design architecture, and system characterization

    International Nuclear Information System (INIS)

    Gupta, Rajiv; Brady, Tom; Grasruck, Michael; Suess, Christoph; Schmidt, Bernhard; Stierstorfer, Karl; Popescu, Stefan; Flohr, Thomas; Bartling, Soenke H.

    2006-01-01

    Digital flat-panel-based volume CT (VCT) represents a unique design capable of ultra-high spatial resolution, direct volumetric imaging, and dynamic CT scanning. This innovation, when fully developed, has the promise of opening a unique window on human anatomy and physiology. For example, the volumetric coverage offered by this technology enables us to observe the perfusion of an entire organ, such as the brain, liver, or kidney, tomographically (e.g., after a transplant or ischemic event). By virtue of its higher resolution, one can directly visualize the trabecular structure of bone. This paper describes the basic design architecture of VCT. Three key technical challenges, viz., scatter correction, dynamic range extension, and temporal resolution improvement, must be addressed for successful implementation of a VCT scanner. How these issues are solved in a VCT prototype and the modifications necessary to enable ultra-high resolution volumetric scanning are described. The fundamental principles of scatter correction and dose reduction are illustrated with the help of an actual prototype. The image quality metrics of this prototype are characterized and compared with a multi-detector CT (MDCT). (orig.)

  19. Clinical investigation of flat panel CT following middle ear reconstruction: a study of 107 patients

    Energy Technology Data Exchange (ETDEWEB)

    Zaoui, K. [University Hospital Heidelberg, Ruprecht Karls University, Department of Otorhinolaryngology, Head and Neck Surgery, Heidelberg (Germany); Kromeier, J. [St. Josefs Hospital, RkK, Department of Radiology, Freiburg (Germany); Neudert, M.; Beleites, T.; Zahnert, T. [University Hospital Dresden, Technical University, Department of Otorhinolaryngology, Head and Neck Surgery, Dresden (Germany); Laszig, R.; Offergeld, C. [University Hospital Freiburg, Albert Ludwigs University, Department of Otorhinolaryngology, Head and Neck Surgery, Freiburg (Germany)

    2014-03-15

    After middle ear reconstruction using partial or total ossicular replacement prostheses (PORP/TORP), an air-bone gap (ABG) may persist because of prosthesis displacement or malposition. So far, CT of the temporal bone has played the main role in the diagnosis of reasons for postoperative insufficient ABG improvement. Recent experimental and clinical studies have evaluated flat panel CT (fpCT) as an alternative imaging technique that provides images with high isovolumetric resolution, fewer metal-induced artefacts and lower irradiation doses. One hundred and seven consecutive patients with chronic otitis media with or without cholesteatoma underwent reconstruction by PORP (n = 52) or TORP (n = 55). All subjects underwent preoperative and postoperative audiometric testing and postoperative fpCT. Statistical evaluation of all 107 patients as well as the sole sub-assembly groups (PORP or TORP) showed a highly significant correlation between hearing improvement and fpCT-determined prosthesis position. FpCT enables detailed postoperative information on patients with middle ear reconstruction. FpCT is a new imaging technique that provides immediate feedback on surgical results after reconstructive middle ear surgery. Specific parameters evaluated by fpCT may serve as a predictive tool for estimated postoperative hearing improvement. Therefore this imaging technique is suitable for postoperative quality control in reconstructive middle ear surgery. (orig.)

  20. Dynamic flat panel detector versus image intensifier in cardiac imaging: dose and image quality

    Science.gov (United States)

    Vano, E.; Geiger, B.; Schreiner, A.; Back, C.; Beissel, J.

    2005-12-01

    The practical aspects of the dosimetric and imaging performance of a digital x-ray system for cardiology procedures were evaluated. The system was configured with an image intensifier (II) and later upgraded to a dynamic flat panel detector (FD). Entrance surface air kerma (ESAK) to phantoms of 16, 20, 24 and 28 cm of polymethyl methacrylate (PMMA) and the image quality of a test object were measured. Images were evaluated directly on the monitor and with numerical methods (noise and signal-to-noise ratio). Information contained in the DICOM header for dosimetry audit purposes was also tested. ESAK values per frame (or kerma rate) for the most commonly used cine and fluoroscopy modes for different PMMA thicknesses and for field sizes of 17 and 23 cm for II, and 20 and 25 cm for FD, produced similar results in the evaluated system with both technologies, ranging between 19 and 589 µGy/frame (cine) and 5 and 95 mGy min-1 (fluoroscopy). Image quality for these dose settings was better for the FD version. The 'study dosimetric report' is comprehensive, and its numerical content is sufficiently accurate. There is potential in the future to set those systems with dynamic FD to lower doses than are possible in the current II versions, especially for digital cine runs, or to benefit from improved image quality.

  1. Ultra-high resolution flat-panel volume CT: fundamental principles, design architecture, and system characterization

    Energy Technology Data Exchange (ETDEWEB)

    Gupta, Rajiv; Brady, Tom [Massachusetts General Hospital, Department of Radiology, Founders House, FND-2-216, Boston, MA (United States); Grasruck, Michael; Suess, Christoph; Schmidt, Bernhard; Stierstorfer, Karl; Popescu, Stefan; Flohr, Thomas [Siemens Medical Solutions, Forchheim (Germany); Bartling, Soenke H. [Hannover Medical School, Department of Neuroradiology, Hannover (Germany)

    2006-06-15

    Digital flat-panel-based volume CT (VCT) represents a unique design capable of ultra-high spatial resolution, direct volumetric imaging, and dynamic CT scanning. This innovation, when fully developed, has the promise of opening a unique window on human anatomy and physiology. For example, the volumetric coverage offered by this technology enables us to observe the perfusion of an entire organ, such as the brain, liver, or kidney, tomographically (e.g., after a transplant or ischemic event). By virtue of its higher resolution, one can directly visualize the trabecular structure of bone. This paper describes the basic design architecture of VCT. Three key technical challenges, viz., scatter correction, dynamic range extension, and temporal resolution improvement, must be addressed for successful implementation of a VCT scanner. How these issues are solved in a VCT prototype and the modifications necessary to enable ultra-high resolution volumetric scanning are described. The fundamental principles of scatter correction and dose reduction are illustrated with the help of an actual prototype. The image quality metrics of this prototype are characterized and compared with a multi-detector CT (MDCT). (orig.)

  2. Peer review panel summary report for technical determination of mixed waste incineration off-gas systems for Rocky Flats

    International Nuclear Information System (INIS)

    1992-01-01

    A Peer Review Panel was convened on September 15-17, 1992 in Boulder, Co. The members of this panel included representatives from DOE, EPA, and DOE contractors along with invited experts in the fields of air pollution control and waste incineration. The primary purpose of this review panel was to make a technical determination of a hold, test and release off gas capture system should be implemented in the proposed RF Pland mixed waste incineration system; or if a state of the art continuous air pollution control and monitoring system should be utilized as the sole off-gas control system. All of the evaluations by the panel were based upon the use of the fluidized bed unit proposed by Rocky Flats and cannot be generalized to other systems

  3. A forward bias method for lag correction of an a-Si flat panel detector

    International Nuclear Information System (INIS)

    Starman, Jared; Tognina, Carlo; Partain, Larry; Fahrig, Rebecca

    2012-01-01

    Purpose: Digital a-Si flat panel (FP) x-ray detectors can exhibit detector lag, or residual signal, of several percent that can cause ghosting in projection images or severe shading artifacts, known as the radar artifact, in cone-beam computed tomography (CBCT) reconstructions. A major contributor to detector lag is believed to be defect states, or traps, in the a-Si layer of the FP. Software methods to characterize and correct for the detector lag exist, but they may make assumptions such as system linearity and time invariance, which may not be true. The purpose of this work is to investigate a new hardware based method to reduce lag in an a-Si FP and to evaluate its effectiveness at removing shading artifacts in CBCT reconstructions. The feasibility of a novel, partially hardware based solution is also examined. Methods: The proposed hardware solution for lag reduction requires only a minor change to the FP. For pulsed irradiation, the proposed method inserts a new operation step between the readout and data collection stages. During this new stage the photodiode is operated in a forward bias mode, which fills the defect states with charge. A Varian 4030CB panel was modified to allow for operation in the forward bias mode. The contrast of residual lag ghosts was measured for lag frames 2 and 100 after irradiation ceased for standard and forward bias modes. Detector step response, lag, SNR, modulation transfer function (MTF), and detective quantum efficiency (DQE) measurements were made with standard and forward bias firmware. CBCT data of pelvic and head phantoms were also collected. Results: Overall, the 2nd and 100th detector lag frame residual signals were reduced 70%-88% using the new method. SNR, MTF, and DQE measurements show a small decrease in collected signal and a small increase in noise. The forward bias hardware successfully reduced the radar artifact in the CBCT reconstruction of the pelvic and head phantoms by 48%-81%. Conclusions: Overall, the

  4. Standard practice for radiologic examination of flat panel composites and sandwich core materials used in aerospace applications

    CERN Document Server

    American Society for Testing and Materials. Philadelphia

    2009-01-01

    1.1 This practice is intended to be used as a supplement to Practices E 1742, E 1255, and E 2033. 1.2 This practice describes procedures for radiologic examination of flat panel composites and sandwich core materials made entirely or in part from fiber-reinforced polymer matrix composites. Radiologic examination is: a) radiographic (RT) with film, b) Computed Radiography (CR) with Imaging Plate, c) Digital Radiology (DR) with Digital Detector Array’s (DDA), and d) Radioscopic (RTR) Real Time Radiology with a detection system such as an Image Intensifier. The composite materials under consideration typically contain continuous high modulus fibers (> 20 GPa), such as those listed in 1.4. 1.3 This practice describes established radiological examination methods that are currently used by industry that have demonstrated utility in quality assurance of flat panel composites and sandwich core materials during product process design and optimization, process control, after manufacture inspection, in service exami...

  5. Development of flat panel X-ray detector utilizing a CdZnTe film as conversion layer

    International Nuclear Information System (INIS)

    Tokuda, Satoshi; Kishihara, Hiroyuki; Kaino, Masatomo; Sato, Toshiyuki

    2006-01-01

    A polycrystalline CdZnTe film formed by the CSS (closed-spaced sublimation) method is one of the most promising materials as a conversion layer of next-generation highly efficient flat-panel X-ray detectors. Therefore, we have developed a prototype of a new flat-panel X-ray detector (a sensing region of 3 inches by 3 inches) with the film and evaluated its commercial feasibility. This paper describes evaluation of the physical and imaging properties of the prototype and explains the features of the CdZnTe film and the construction, specifications, and fabrication procedures of the prototype. Also included in this paper are formation of a semiconductor thin film barrier layer by the CBD (chemical bath deposition) method and conjunction of a sensor substrate and a TFT array substrate with the bump electrodes formed by screen printing, both of which we have developed during the course of the development of the prototype. (author)

  6. Modeling on the cathodoluminescence properties of the thin film phosphors for field emission flat panel displays

    Science.gov (United States)

    Cho, Kyu-Gong

    2000-12-01

    utilized to optimize the thin film phosphor properties for the application of field emission flat panel displays.

  7. Normalized glandular dose (DgN) coefficients for flat-panel CT breast imaging

    International Nuclear Information System (INIS)

    Thacker, Samta C; Glick, Stephen J

    2004-01-01

    The development of new digital mammography techniques such as dual-energy imaging, tomosynthesis and CT breast imaging will require investigation of optimal camera design parameters and optimal imaging acquisition parameters. In optimizing these acquisition protocols and imaging systems it is important to have knowledge of the radiation dose to the breast. This study presents a methodology for estimating the normalized glandular dose to the uncompressed breast using the geometry proposed for flat-panel CT breast imaging. The simulation uses the GEANT 3 Monte Carlo code to model x-ray transport and absorption within the breast phantom. The Monte Carlo software was validated for breast dosimetry by comparing results of the normalized glandular dose (DgN) values of the compressed breast to those reported in the literature. The normalized glandular dose was then estimated for a range of breast diameters from 10 cm to 18 cm using an uncompressed breast model with a homogeneous composition of adipose and glandular tissue, and for monoenergetic x-rays from 10 keV to 120 keV. These data were fit providing expressions for the normalized glandular dose. Using these expressions for the DgN coefficients and input variables such as the diameter, height and composition of the breast phantom, the mean glandular dose for any spectra can be estimated. A computer program to provide normalized glandular dose values has been made available online. In addition, figures displaying energy deposition maps are presented to better understand the spatial distribution of dose in CT breast imaging

  8. Influence of Flat-Panel Fluoroscopic Equipment Variables on Cardiac Radiation Doses

    International Nuclear Information System (INIS)

    Nickoloff, Edward L.; Lu Zhengfeng; Dutta, Ajoy; So, James; Balter, Stephen; Moses, Jeffrey

    2007-01-01

    Purpose. To assess the influence of physician-selectable equipment variables on the potential radiation dose reductions during cardiac catheterization examinations using modern imaging equipment. Materials. A modern bi-plane angiography unit with flat-panel image receptors was used. Patients were simulated with 15-30 cm of acrylic plastic. The variables studied were: patient thickness, fluoroscopy pulse rates, record mode frame rates, image receptor field-of-view (FoV), automatic dose control (ADC) mode, SID/SSD geometry setting, automatic collimation, automatic positioning, and others. Results. Patient radiation doses double for every additional 3.5-4.5 cm of soft tissue. The dose is directly related to the imaging frame rate; a decrease from 30 pps to 15 pps reduces the dose by about 50%. The dose is related to [(FoV) -N ] where 2.0 < N < 3.0. Suboptimal positioning of the patient can nearly double the dose. The ADC system provides three selections that can vary the radiation level by 50%. For pediatric studies (2-5 years old), the selection of equipment variables can result in entrance radiation doses that range between 6 and 60 cGy for diagnostic cases and between 15 and 140 cGy for interventional cases. For adult studies, the equipment variables can produce entrance radiation doses that range between 13 and 130 cGy for diagnostic cases and between 30 and 400 cGy for interventional cases. Conclusions. Overall dose reductions of 70-90% can be achieved with pediatric patients and about 90% with adult patients solely through optimal selection of equipment variables

  9. Leaf trajectory verification during dynamic intensity modulated radiotherapy using an amorphous silicon flat panel imager

    International Nuclear Information System (INIS)

    Sonke, Jan-Jakob; Ploeger, Lennert S.; Brand, Bob; Smitsmans, Monique H.P.; Herk, Marcel van

    2004-01-01

    An independent verification of the leaf trajectories during each treatment fraction improves the safety of IMRT delivery. In order to verify dynamic IMRT with an electronic portal imaging device (EPID), the EPID response should be accurate and fast such that the effect of motion blurring on the detected moving field edge position is limited. In the past, it was shown that the errors in the detected position of a moving field edge determined by a scanning liquid-filled ionization chamber (SLIC) EPID are negligible in clinical practice. Furthermore, a method for leaf trajectory verification during dynamic IMRT was successfully applied using such an EPID. EPIDs based on amorphous silicon (a-Si) arrays are now widely available. Such a-Si flat panel imagers (FPIs) produce portal images with superior image quality compared to other portal imaging systems, but they have not yet been used for leaf trajectory verification during dynamic IMRT. The aim of this study is to quantify the effect of motion distortion and motion blurring on the detection accuracy of a moving field edge for an Elekta iViewGT a-Si FPI and to investigate its applicability for the leaf trajectory verification during dynamic IMRT. We found that the detection error for a moving field edge to be smaller than 0.025 cm at a speed of 0.8 cm/s. Hence, the effect of motion blurring on the detection accuracy of a moving field edge is negligible in clinical practice. Furthermore, the a-Si FPI was successfully applied for the verification of dynamic IMRT. The verification method revealed a delay in the control system of the experimental DMLC that was also found using a SLIC EPID, resulting in leaf positional errors of 0.7 cm at a leaf speed of 0.8 cm/s

  10. MO-AB-BRA-07: Low Dose Imaging with Avalanche Amorphous Selenium Flat Panel Imager

    Energy Technology Data Exchange (ETDEWEB)

    Scheuermann, J; Howansky, A; Goldan, A; Tanioka, K; Zhao, W [Stony Brook University, Stony Brook, New York (United States); Leveille, S; Tousignant, O [2Analogic Canada, Saint-laurent, Quebec (Canada)

    2016-06-15

    Purpose: We present the first active matrix flat panel imager (AMFPI) capable of producing x-ray quantum noise limited images at low doses by overcoming the electronic noise through signal amplification by photoconductive avalanche gain (gav). The indirect detector fabricated uses an optical sensing layer of amorphous selenium (a-Se) known as High-Gain Avalanche Rushing Photoconductor (HARP). The detector design is called Scintillator HARP (SHARP)-AMFPI. This is the first image sensor to utilize solid-state HARP technology. Methods: The detector’s electronic readout is a 24 × 30 cm{sup 2} array of thin film transistors (TFT) with a pixel pitch of 85 µm. The HARP structure consists of a 15 µm layer of a-Se isolated from the high voltage (HV) and signal electrode by a 2 µm thick hole blocking layer and electron blocking layer, respectively, to reduce dark current. A 150 µm thick structured CsI scintillator with reflective backing and a fiber optic faceplate (FOP) was coupled to the semi-transparent HV bias electrode of the HARP structure. Images were acquired using a 30 kVp Mo/Mo spectrum typically used in mammography. Results: Optical sensitivity measurements demonstrate that gav = 76 ± 5 can be achieved over the entire active area of the detector. At a constant dose to the detector of 6.67 µGy, image quality increases with gav until the effective electronic noise is negligible. Quantum noise limited images can be obtained with doses as low as 0.18 µGy. Conclusion: We demonstrate the feasibility of utilizing avalanche gain to overcome electronic noise. The indirect detector fabricated is the first solid-state imaging sensor to use HARP, and the largest active area HARP sensor to date. Our future work is to improve charge transport within the HARP structure and utilize a transparent HV electrode.

  11. Evaluation of patient exposure with Flat Panel Detector (FPD) in X-ray TV system

    International Nuclear Information System (INIS)

    Yamada, M.; Komiya, N.; Kawaguchi, A.; Suzuki, M.; Suzuki, Shoichi; Asada, Yasuki

    2008-01-01

    The use of flat-panel detector (FPD) systems in TV equipment for gastrointestinal tract examination is increasing. The use of FPD systems is believed to reduce the exposure dose. When our institution changed its TV equipment from an image intensifier (GE; MS90Tj) system to an FPD (Shimadzu; SONIALVISION safire DAR-3500) system, we measured the doses produced and carried out a comparative examination of the extent to which exposure could be reduced. Two TV systems were used. We used an analyzer to measure output waveform, tube voltage, and half-value layer (HVL), and an ionization chamber dosimeter to carry out dose-in-air measurements. Body thickness, number of image acquisitions, and fluoroscopy time are required for the calculation of entrance skin dose (ESD). We therefore measured body thicknesses in 1000 upper gastrointestinal tract (UGI) and barium enemas and obtained average body thicknesses for males and females by age group. Values used for number of image acquisitions and fluoroscopy times were the averages in our institution over a two-year period. When an I.I. system was used, the average ESD during UGI examination were 126.8 mGy fluoroscopy dose and 11.62 mGy imaging dose, for an average total dose of 138.42 mGy per examination. ESD during barium enema averaged 201.73 mGy fluoroscopy dose and 45.2 mGy imaging dose, for an average total dose of 246.92 mGy per examination. When an FPD system was used, the average ESD during UGI examination were 58.71 mGy fluoroscopy dose and 5.72 mGy imaging dose, for an average total dose of 64.43 mGy per examination. ESD during barium enema averaged 112.21 mGy fluoroscopy dose and 24.55 mGy imaging dose, for an average total dose of 136.76 mGy per examination. The use of an FPD system reduced both fluoroscopy dose and imaging dose by 50%. The number of TV systems equipped with FPD in Japan has increased from around 1300 in 2006 to around 1700 in 2007. The use of FPD systems can be expected to increase in future. This

  12. Measurement of joint kinematics using a conventional clinical single-perspective flat-panel radiography system

    International Nuclear Information System (INIS)

    Seslija, Petar; Teeter, Matthew G.; Yuan Xunhua; Naudie, Douglas D. R.; Bourne, Robert B.; MacDonald, Steven J.; Peters, Terry M.; Holdsworth, David W.

    2012-01-01

    Purpose: The ability to accurately measure joint kinematics is an important tool in studying both normal joint function and pathologies associated with injury and disease. The purpose of this study is to evaluate the efficacy, accuracy, precision, and clinical safety of measuring 3D joint motion using a conventional flat-panel radiography system prior to its application in an in vivo study. Methods: An automated, image-based tracking algorithm was implemented to measure the three-dimensional pose of a sparse object from a two-dimensional radiographic projection. The algorithm was tested to determine its efficiency and failure rate, defined as the number of image frames where automated tracking failed, or required user intervention. The accuracy and precision of measuring three-dimensional motion were assessed using a robotic controlled, tibiofemoral knee phantom programmed to mimic a subject with a total knee replacement performing a stair ascent activity. Accuracy was assessed by comparing the measurements of the single-plane radiographic tracking technique to those of an optical tracking system, and quantified by the measurement discrepancy between the two systems using the Bland–Altman technique. Precision was assessed through a series of repeated measurements of the tibiofemoral kinematics, and was quantified using the across-trial deviations of the repeated kinematic measurements. The safety of the imaging procedure was assessed by measuring the effective dose of ionizing radiation associated with the x-ray exposures, and analyzing its relative risk to a human subject. Results: The automated tracking algorithm displayed a failure rate of 2% and achieved an average computational throughput of 8 image frames/s. Mean differences between the radiographic and optical measurements for translations and rotations were less than 0.08 mm and 0.07° in-plane, and 0.24 mm and 0.6° out-of-plane. The repeatability of kinematics measurements performed using the

  13. An investigation of flat panel equipment variables on image quality with a dedicated cardiac phantom

    International Nuclear Information System (INIS)

    Dragusin, O; Bosmans, H; Pappas, C; Desmet, W

    2008-01-01

    Image quality (IQ) evaluation plays a key role in the process of optimization of new x-ray systems. Ideally, this process should be supported by real clinical images, but ethical issues and differences in anatomy and pathology of patients make it impossible. Phantom studies might overcome these issues. This paper presents the IQ evaluation of 30 cineangiographic films acquired with a cardiac flat panel system. The phantom used simulates the anatomy of the heart and allows the circulation of contrast agent boluses through coronary arteries. Variables investigated with influence on IQ and radiation dose are: tube potential, detector dose, added Copper filters, dynamic density optimization (DDO) and viewing angle. The IQ evaluation consisted of scoring 4 simulated calcified lesions located on different coronary artery segments in terms of degree of visualization. Eight cardiologists rated the lesions using a five-point scale ((1) lesion not visible to (5) very good visibility). Radiation doses associated to the angiograms are expressed in terms of incident air kerma (IAK) and effective dose that has been calculated with PCXMX software (STUK, Finland) from the exposure settings assuming a standard sized patient of 70 Kg. Mean IQ scores ranged from 1.68 to 4.88. The highest IQ scores were obtained for the angiograms acquired with tube potential 80 kVp, no added Cu filters, DDO 60%, RAO and LAO views and the highest entrance detector dose that has been used in the present study, namely 0.17 μGy/im. Radiation doses (IAK ∼40 mGy and effective dose of 1 mSv) were estimated for angiograms acquired at 15 frames s -1 , detector field-of-view 20 cm, and a length of 5 s. The following parameters improved the IQ factor significantly: a change in tube potential from 96 to 80 kVp, detector dose from 0.10 μGy/im to 0.17 μGy/im, the absence of Copper filtration. DDO variable which is a post-processing parameter should be carefully evaluated because it alters the quality of the

  14. Amorphous and Polycrystalline Photoconductors for Direct Conversion Flat Panel X-Ray Image Sensors

    Directory of Open Access Journals (Sweden)

    Karim S. Karim

    2011-05-01

    Full Text Available In the last ten to fifteen years there has been much research in using amorphous and polycrystalline semiconductors as x-ray photoconductors in various x-ray image sensor applications, most notably in flat panel x-ray imagers (FPXIs. We first outline the essential requirements for an ideal large area photoconductor for use in a FPXI, and discuss how some of the current amorphous and polycrystalline semiconductors fulfill these requirements. At present, only stabilized amorphous selenium (doped and alloyed a-Se has been commercialized, and FPXIs based on a-Se are particularly suitable for mammography, operating at the ideal limit of high detective quantum efficiency (DQE. Further, these FPXIs can also be used in real-time, and have already been used in such applications as tomosynthesis. We discuss some of the important attributes of amorphous and polycrystalline x-ray photoconductors such as their large area deposition ability, charge collection efficiency, x-ray sensitivity, DQE, modulation transfer function (MTF and the importance of the dark current. We show the importance of charge trapping in limiting not only the sensitivity but also the resolution of these detectors. Limitations on the maximum acceptable dark current and the corresponding charge collection efficiency jointly impose a practical constraint that many photoconductors fail to satisfy. We discuss the case of a-Se in which the dark current was brought down by three orders of magnitude by the use of special blocking layers to satisfy the dark current constraint. There are also a number of polycrystalline photoconductors, HgI2 and PbO being good examples, that show potential for commercialization in the same way that multilayer stabilized a-Se x-ray photoconductors were developed for commercial applications. We highlight the unique nature of avalanche multiplication in a-Se and how it has led to the development of the commercial HARP video-tube. An all solid state version of the

  15. An investigation of flat panel equipment variables on image quality with a dedicated cardiac phantom

    Energy Technology Data Exchange (ETDEWEB)

    Dragusin, O; Bosmans, H [Department of Radiology, University Hospital Gasthuisberg, 49, Herestraat, 3000-Leuven (Belgium); Pappas, C; Desmet, W [Department of Cardiology, University Hospital Gasthuisberg, 49, Herestraat, 3000-Leuven (Belgium)], E-mail: odragusin@yahoo.com

    2008-09-21

    Image quality (IQ) evaluation plays a key role in the process of optimization of new x-ray systems. Ideally, this process should be supported by real clinical images, but ethical issues and differences in anatomy and pathology of patients make it impossible. Phantom studies might overcome these issues. This paper presents the IQ evaluation of 30 cineangiographic films acquired with a cardiac flat panel system. The phantom used simulates the anatomy of the heart and allows the circulation of contrast agent boluses through coronary arteries. Variables investigated with influence on IQ and radiation dose are: tube potential, detector dose, added Copper filters, dynamic density optimization (DDO) and viewing angle. The IQ evaluation consisted of scoring 4 simulated calcified lesions located on different coronary artery segments in terms of degree of visualization. Eight cardiologists rated the lesions using a five-point scale ((1) lesion not visible to (5) very good visibility). Radiation doses associated to the angiograms are expressed in terms of incident air kerma (IAK) and effective dose that has been calculated with PCXMX software (STUK, Finland) from the exposure settings assuming a standard sized patient of 70 Kg. Mean IQ scores ranged from 1.68 to 4.88. The highest IQ scores were obtained for the angiograms acquired with tube potential 80 kVp, no added Cu filters, DDO 60%, RAO and LAO views and the highest entrance detector dose that has been used in the present study, namely 0.17 {mu}Gy/im. Radiation doses (IAK {approx}40 mGy and effective dose of 1 mSv) were estimated for angiograms acquired at 15 frames s{sup -1}, detector field-of-view 20 cm, and a length of 5 s. The following parameters improved the IQ factor significantly: a change in tube potential from 96 to 80 kVp, detector dose from 0.10 {mu}Gy/im to 0.17 {mu}Gy/im, the absence of Copper filtration. DDO variable which is a post-processing parameter should be carefully evaluated because it alters the

  16. A performance comparison of direct- and indirect-detection flat-panel imagers

    International Nuclear Information System (INIS)

    Partridge, M.; Hesse, B.-M.; Mueller, L.

    2002-01-01

    A comparison of the performance of a direct- and an indirect-detection amorphous silicon flat-panel X-ray imager is presented for a 6 MV beam. Experimental measurements of the noise characteristics, image lag, spectral response, spatial resolution and quantum efficiency are described, compared and discussed. The two systems are comprised of 512x512 pixel, 400 μm pitch, arrays of a-Si:H p-i-n photodiodes and thin-film transistors. In the direct-detection system, X-rays interact to produce electron/hole pairs directly in the silicon photodiodes. For the indirect-detection system, a phosphor screen converts energy from the incident X-rays into visible light, which is then detected by the photodiodes. Both systems are shown to be quantum noise limited, with the total electronic noise in the detector 10-15 times smaller than the Poisson noise level in detected signal. The measured lag for both systems is 1.0±0.1% or less in the first frame with subsequent signals decaying exponentially with frame read-out, with a half-life of between 3.3 and 3.8 frames. Both systems are demonstrated to have a pronounced sensitivity to low-energy multiply scattered photons, although this is shown to be effectively filtered out using a 2 mm copper build-up plate. The direct-detection system, with the 2 mm Cu build-up, shows greater sensitivity to scattered radiation than the indirect system. The spatial resolutions of both systems were effectively equal with an f 50 of 0.25 mm -1 when pixels are binned 2x2, although a slight contribution from optical scattering in the phosphor screen is seen for the indirect-detection system. The quantum efficiency of the direct-detection system is a factor of 0.45 lower than that of the indirect-detection system. The application of these detectors to megavoltage CT is discussed, with the conclusion that the indirect-detection system is to be preferred

  17. Optimization of a flat-panel based real time dual-energy system for cardiac imaging

    International Nuclear Information System (INIS)

    Ducote, Justin L.; Xu Tong; Molloi, Sabee

    2006-01-01

    A simulation study was conducted to evaluate the effects of high-energy beam filtration, dual-gain operation and noise reduction on dual-energy images using a digital flat-panel detector. High-energy beam filtration increases image contrast through greater beam separation and tends to reduce total radiation exposure and dose per image pair. It is also possible to reduce dual-energy image noise by acquiring low and high-energy images at two different detector gains. In addition, dual-energy noise reduction algorithms can further reduce image noise. The cumulative effect of these techniques applied in series was investigated in this study. The contrast from a small thickness of calcium was simulated over a step phantom of tissue equivalent material with a CsI phosphor as the image detector. The dual-energy contrast-to-noise ratio was calculated using values of energy absorption and energy variance. A figure-of-merit (FOM) was calculated from dual-energy contrast-to-noise ratio (CNR) and patient effective dose estimated from values of entrance exposure. Filter atomic numbers in the range of 1-100 were considered with thicknesses ranging from 0-2500 mg/cm 2 . The simulation examined combinations of the above techniques which maximized the FOM. The application of a filter increased image contrast by as much as 45%. Near maximal increases were seen for filter atomic numbers in the range of 40-60 and 85-100 with masses above 750 mg/cm 2 . Increasing filter thickness beyond 1000 mg/cm 2 increased tube loading without further significant contrast enhancement. No additional FOM improvements were seen with dual gain before or after the application of any noise reduction algorithm. Narrow beam experiments were carried out to verify predictions. The measured FOM increased by more than a factor of 3.5 for a silver filter thickness of 800 μm, equal energy weighting and application of a noise clipping algorithm. The main limitation of dynamic high-energy filtration is increased

  18. Compact muon solenoid magnet reaches full field

    CERN Multimedia

    2006-01-01

    Scientist of the U.S. Department of Energy in Fermilab and collaborators of the US/CMS project announced that the world's largest superconducting solenoid magnet has reached full field in tests at CERN. (1 apge)

  19. Calibration model of a dual gain flat panel detector for 2D and 3D x-ray imaging

    International Nuclear Information System (INIS)

    Schmidgunst, C.; Ritter, D.; Lang, E.

    2007-01-01

    The continuing research and further development in flat panel detector technology have led to its integration into more and more medical x-ray systems for two-dimensional (2D) and three-dimensional (3D) imaging, such as fixed or mobile C arms. Besides the obvious advantages of flat panel detectors, like the slim design and the resulting optimum accessibility to the patient, their success is primarily a product of the image quality that can be achieved. The benefits in the physical and performance-related features as opposed to conventional image intensifier systems (e.g., distortion-free reproduction of imaging information or almost linear signal response over a large dynamic range) can be fully exploited, however, only if the raw detector images are correctly calibrated and postprocessed. Previous procedures for processing raw data contain idealizations that, in the real world, lead to artifacts or losses in image quality. Thus, for example, temperature dependencies or changes in beam geometry, as can occur with mobile C arm systems, have not been taken into account up to this time. Additionally, adverse characteristics such as image lag or aging effects have to be compensated to attain the best possible image quality. In this article a procedure is presented that takes into account the important dependencies of the individual pixel sensitivity of flat panel detectors used in 2D or 3D imaging and simultaneously minimizes the work required for an extensive recalibration. It is suitable for conventional detectors with only one gain mode as well as for the detectors specially developed for 3D imaging with dual gain read-out technology

  20. Radiation dose reduction using a CdZnTe-based computed tomography system: Comparison to flat-panel detectors

    Energy Technology Data Exchange (ETDEWEB)

    Le, Huy Q.; Ducote, Justin L.; Molloi, Sabee [Department of Radiological Sciences, University of California, Irvine, California 92697 (United States)

    2010-03-15

    Purpose: Although x-ray projection mammography has been very effective in early detection of breast cancer, its utility is reduced in the detection of small lesions that are occult or in dense breasts. One drawback is that the inherent superposition of parenchymal structures makes visualization of small lesions difficult. Breast computed tomography using flat-panel detectors has been developed to address this limitation by producing three-dimensional data while at the same time providing more comfort to the patients by eliminating breast compression. Flat panels are charge integrating detectors and therefore lack energy resolution capability. Recent advances in solid state semiconductor x-ray detector materials and associated electronics allow the investigation of x-ray imaging systems that use a photon counting and energy discriminating detector, which is the subject of this article. Methods: A small field-of-view computed tomography (CT) system that uses CdZnTe (CZT) photon counting detector was compared to one that uses a flat-panel detector for different imaging tasks in breast imaging. The benefits afforded by the CZT detector in the energy weighting modes were investigated. Two types of energy weighting methods were studied: Projection based and image based. Simulation and phantom studies were performed with a 2.5 cm polymethyl methacrylate (PMMA) cylinder filled with iodine and calcium contrast objects. Simulation was also performed on a 10 cm breast specimen. Results: The contrast-to-noise ratio improvements as compared to flat-panel detectors were 1.30 and 1.28 (projection based) and 1.35 and 1.25 (image based) for iodine over PMMA and hydroxylapatite over PMMA, respectively. Corresponding simulation values were 1.81 and 1.48 (projection based) and 1.85 and 1.48 (image based). Dose reductions using the CZT detector were 52.05% and 49.45% for iodine and hydroxyapatite imaging, respectively. Image-based weighting was also found to have the least beam

  1. Radiation dose reduction using a CdZnTe-based computed tomography system: Comparison to flat-panel detectors

    International Nuclear Information System (INIS)

    Le, Huy Q.; Ducote, Justin L.; Molloi, Sabee

    2010-01-01

    Purpose: Although x-ray projection mammography has been very effective in early detection of breast cancer, its utility is reduced in the detection of small lesions that are occult or in dense breasts. One drawback is that the inherent superposition of parenchymal structures makes visualization of small lesions difficult. Breast computed tomography using flat-panel detectors has been developed to address this limitation by producing three-dimensional data while at the same time providing more comfort to the patients by eliminating breast compression. Flat panels are charge integrating detectors and therefore lack energy resolution capability. Recent advances in solid state semiconductor x-ray detector materials and associated electronics allow the investigation of x-ray imaging systems that use a photon counting and energy discriminating detector, which is the subject of this article. Methods: A small field-of-view computed tomography (CT) system that uses CdZnTe (CZT) photon counting detector was compared to one that uses a flat-panel detector for different imaging tasks in breast imaging. The benefits afforded by the CZT detector in the energy weighting modes were investigated. Two types of energy weighting methods were studied: Projection based and image based. Simulation and phantom studies were performed with a 2.5 cm polymethyl methacrylate (PMMA) cylinder filled with iodine and calcium contrast objects. Simulation was also performed on a 10 cm breast specimen. Results: The contrast-to-noise ratio improvements as compared to flat-panel detectors were 1.30 and 1.28 (projection based) and 1.35 and 1.25 (image based) for iodine over PMMA and hydroxylapatite over PMMA, respectively. Corresponding simulation values were 1.81 and 1.48 (projection based) and 1.85 and 1.48 (image based). Dose reductions using the CZT detector were 52.05% and 49.45% for iodine and hydroxyapatite imaging, respectively. Image-based weighting was also found to have the least beam

  2. Dynamic Modeling of the Microalgae Cultivation Phase for Energy Production in Open Raceway Ponds and Flat Panel Photobioreactors

    Energy Technology Data Exchange (ETDEWEB)

    Marsullo, Matteo [Department of Industrial Engineering, University of Padova, Padova (Italy); Mian, Alberto [Industrial Process and Energy System Engineering Group (IPESE), École Polytechnique Fédérale de Lausanne, Lausanne (Switzerland); Ensinas, Adriano Viana [Industrial Process and Energy System Engineering Group (IPESE), École Polytechnique Fédérale de Lausanne, Lausanne (Switzerland); Universidade Federal do ABC, Santo Andre (Brazil); Manente, Giovanni; Lazzaretto, Andrea, E-mail: andrea.lazzaretto@unipd.it [Department of Industrial Engineering, University of Padova, Padova (Italy); Marechal, François [Industrial Process and Energy System Engineering Group (IPESE), École Polytechnique Fédérale de Lausanne, Lausanne (Switzerland)

    2015-09-15

    A dynamic model of microalgae cultivation phase is presented in this work. Two cultivation technologies are taken into account: the open raceway pond and the flat panel photobioreactor. For each technology, the model is able to evaluate the microalgae areal and volumetric productivity and the energy production and consumption. Differently from the most common existing models in literature, which deal with a specific part of the overall cultivation process, the model presented here includes all physical and chemical quantities that mostly affect microalgae growth: the equation of the specific growth rate for the microalgae is influenced by CO{sub 2} and nutrients concentration in the water, light intensity, temperature of the water in the reactor, and by the microalgae species being considered. All these input parameters can be tuned to obtain reliable predictions. A comparison with experimental data taken from the literature shows that the predictions are consistent and slightly overestimating the productivity in the case of closed photobioreactor. The results obtained by the simulation runs are consistent with those found in literature, being the areal productivity for the open raceway pond between 50 and 70 t/(ha × year) in Southern Spain (Sevilla) and Brazil (Petrolina) and between 250 and 350 t/(ha × year) for the flat panel photobioreactor in the same locations.

  3. Nitrogen incorporated ultrananocrystalline diamond based field emitter array for a flat-panel x-ray source

    International Nuclear Information System (INIS)

    Posada, Chrystian M.; Grant, Edwin J.; Lee, Hyoung K.; Castaño, Carlos H.; Divan, Ralu; Sumant, Anirudha V.; Rosenmann, Daniel; Stan, Liliana

    2014-01-01

    A field emission based flat-panel transmission x-ray source is being developed as an alternative for medical and industrial imaging. A field emitter array (FEA) prototype based on nitrogen incorporated ultrananocrystalline diamond film has been fabricated to be used as the electron source of this flat panel x-ray source. The FEA prototype was developed using conventional microfabrication techniques. The field emission characteristics of the FEA prototype were evaluated. Results indicated that emission current densities of the order of 6 mA/cm 2 could be obtained at electric fields as low as 10 V/μm to 20 V/μm. During the prototype microfabrication process, issues such as delamination of the extraction gate and poor etching of the SiO 2 insulating layer located between the emitters and the extraction layer were encountered. Consequently, alternative FEA designs were investigated. Experimental and simulation data from the first FEA prototype were compared and the results were used to evaluate the performance of alternative single and double gate designs that would yield better field emission characteristics compared to the first FEA prototype. The best simulation results are obtained for the double gate FEA design, when the diameter of the collimator gate is around 2.6 times the diameter of the extraction gate

  4. High resolution X-ray imaging of bone-implant interface by large area flat-panel detector

    International Nuclear Information System (INIS)

    Kytyr, D; Jirousek, O; Dammer, J

    2011-01-01

    The aim of the research was to investigate the cemented bone-implant interface behavior (cement layer degradation and bone-cement interface debonding) with emphasis on imaging techniques suitable to detect the early defects in the cement layer. To simulate in vivo conditions a human pelvic bone was implanted with polyurethane acetabular cup using commercial acrylic bone cement. The implanted cup was then loaded in a custom hip simulator to initiate fatigue crack propagation in the bone cement. The pelvic bone was then repetitively scanned in a micro-tomography device. Reconstructed tomography images showed failure processes that occurred in the cement layer during the first 250,000 cycles. A failure in cemented acetabular implant - debonding, crumbling and smeared cracks - has been found to be at the bone-cement interface. Use of micro-focus source and high resolution flat panel detector of large physical dimensions allowed to reconstruct the micro-structural models suitable for investigation of migration, micro-motions and consecutive loosening of the implant. The large area flat panel detector with physical dimensions 120 x 120mm with 50μm pixel size provided a superior image quality compared to clinical CT systems with 300-150μm pixel size.

  5. Dynamic modeling of the microalgae cultivation phase for energy production in open raceway ponds and flat panel photobioreactors

    Directory of Open Access Journals (Sweden)

    Matteo eMarsullo

    2015-09-01

    Full Text Available A dynamic model of microalgae cultivation phase is presented in this work. Two cultivation technologies are taken into account: the open raceway pond and the flat panel photobioreactor. For each technology, the model is able to evaluate the microalgae areal and volumetric productivity and the energy production and consumption. Differently from the most common existing models in literature, which deal with a specific part of the overall cultivation process, the model presented here includes all physical and chemical quantities that mostly affect microalgae growth: the equation of the specific growth rate for the microalgae is influenced by CO2 and nutrients concentration in the water, light intensity, temperature of the water in the reactor and by the microalgae species being considered. All these input parameters can be tuned to obtain reliable predictions. A comparison with experimental data taken from the literature shows that the predictions are consistent, slightly overestimating the productivity in case of closed photobioreactor. The results obtained by the simulation runs are consistent with those found in literature, being the areal productivity for the open raceway pond between 50 and 70 t/(ha*year in Southern Spain (Sevilla and Brazil (Petrolina and between 250 and 350 t/(ha*year for the flat panel photobioreactor in the same locations.

  6. Coupled Electro-Magneto-Mechanical-Acoustic Analysis Method Developed by Using 2D Finite Element Method for Flat Panel Speaker Driven by Magnetostrictive-Material-Based Actuator

    Science.gov (United States)

    Yoo, Byungjin; Hirata, Katsuhiro; Oonishi, Atsurou

    In this study, a coupled analysis method for flat panel speakers driven by giant magnetostrictive material (GMM) based actuator was developed. The sound field produced by a flat panel speaker that is driven by a GMM actuator depends on the vibration of the flat panel, this vibration is a result of magnetostriction property of the GMM. In this case, to predict the sound pressure level (SPL) in the audio-frequency range, it is necessary to take into account not only the magnetostriction property of the GMM but also the effect of eddy current and the vibration characteristics of the actuator and the flat panel. In this paper, a coupled electromagnetic-structural-acoustic analysis method is presented; this method was developed by using the finite element method (FEM). This analysis method is used to predict the performance of a flat panel speaker in the audio-frequency range. The validity of the analysis method is verified by comparing with the measurement results of a prototype speaker.

  7. Reduction of ring artifacts in CBCT: Detection and correction of pixel gain variations in flat panel detectors

    International Nuclear Information System (INIS)

    Altunbas, Cem; Lai, Chao-Jen; Zhong, Yuncheng; Shaw, Chris C.

    2014-01-01

    Purpose: In using flat panel detectors (FPD) for cone beam computed tomography (CBCT), pixel gain variations may lead to structured nonuniformities in projections and ring artifacts in CBCT images. Such gain variations can be caused by change in detector entrance exposure levels or beam hardening, and they are not accounted by conventional flat field correction methods. In this work, the authors presented a method to identify isolated pixel clusters that exhibit gain variations and proposed a pixel gain correction (PGC) method to suppress both beam hardening and exposure level dependent gain variations. Methods: To modulate both beam spectrum and entrance exposure, flood field FPD projections were acquired using beam filters with varying thicknesses. “Ideal” pixel values were estimated by performing polynomial fits in both raw and flat field corrected projections. Residuals were calculated by taking the difference between measured and ideal pixel values to identify clustered image and FPD artifacts in flat field corrected and raw images, respectively. To correct clustered image artifacts, the ratio of ideal to measured pixel values in filtered images were utilized as pixel-specific gain correction factors, referred as PGC method, and they were tabulated as a function of pixel value in a look-up table. Results: 0.035% of detector pixels lead to clustered image artifacts in flat field corrected projections, where 80% of these pixels were traced back and linked to artifacts in the FPD. The performance of PGC method was tested in variety of imaging conditions and phantoms. The PGC method reduced clustered image artifacts and fixed pattern noise in projections, and ring artifacts in CBCT images. Conclusions: Clustered projection image artifacts that lead to ring artifacts in CBCT can be better identified with our artifact detection approach. When compared to the conventional flat field correction method, the proposed PGC method enables characterization of nonlinear

  8. Three-Dimensional Exact Free Vibration Analysis of Spherical, Cylindrical, and Flat One-Layered Panels

    Directory of Open Access Journals (Sweden)

    Salvatore Brischetto

    2014-01-01

    equilibrium written in orthogonal curvilinear coordinates for the free vibrations of simply supported structures. These equations consider an exact geometry for shells without simplifications. The main novelty is the possibility of a general formulation for different geometries. The equations written in general orthogonal curvilinear coordinates allow the analysis of spherical shell panels and they automatically degenerate into cylindrical shell panel, cylindrical closed shell, and plate cases. Results are proposed for isotropic and orthotropic structures. An exhaustive overview is given of the vibration modes for a number of thickness ratios, imposed wave numbers, geometries, embedded materials, and angles of orthotropy. These results can also be used as reference solutions to validate two-dimensional models for plates and shells in both analytical and numerical form (e.g., closed solutions, finite element method, differential quadrature method, and global collocation method.

  9. Prediction of the niche effect for single flat panels with or without attached sound absorbing materials.

    Science.gov (United States)

    Sgard, Franck; Atalla, Noureddine; Nélisse, Hugues

    2015-01-01

    The sound transmission loss (STL) of a test sample measured in sound transmission facilities is affected by the opening in which it is located. This is called the niche effect. This paper uses a modal approach to study the STL of a rectangular plate with or without an attached porous material located inside a box-shaped niche. The porous material is modeled as a limp equivalent fluid. The proposed model is validated by comparison with finite element/boundary element computations. Using a condensation of the pressure fields in the niche, the niche effect is interpreted in terms of a modification of the modal blocked pressure fields acting on the panel induced by the front cavity and by a modification of the radiation efficiency of the panel modes due to the presence of the back cavity. The modal approach is then used to investigate the impact of (1) the presence of a porous material attached to the panel on the niche effect and (2) the niche effect on the assessment of the porous material insertion loss. A simplified model for the porous material based on a transfer matrix approach is also proposed to predict the STL of the system and its validity is discussed.

  10. Lag and ghosting in a clinical flat-panel selenium digital mammography system

    International Nuclear Information System (INIS)

    Bloomquist, Aili K.; Yaffe, Martin J.; Mawdsley, Gordon E.; Hunter, David M.; Beideck, Daniel J.

    2006-01-01

    We present measurements of lag and ghosting in a FDA-approved digital mammography system that uses a dielectric/selenium based detector structure. Lag is the carryover of signal from a previous image, whereas ghosting is the reduction of sensitivity caused by previous exposure history of the detector. Data from six selenium units were acquired. For the type of selenium detector tested, and under typical clinical usage conditions, the lag was as high as 0.15% of source signal and the ghosting could be as high as 15%. The amount of lag and ghosting varied from unit to unit. Results were compared with data acquired on a phosphor-based full-field digital mammography system. Modifications in the technology of the selenium detectors appear to have resulted in a marked decrease in both lag and ghosting effects in more recent systems

  11. Cone-Beam CT with Flat-Panel-Detector Digital Angiography System: Early Experience in Abdominal Interventional Procedures

    International Nuclear Information System (INIS)

    Hirota, Shozo; Nakao, Norio; Yamamoto, Satoshi; Kobayashi, Kaoru; Maeda, Hiroaki; Ishikura, Reiichi; Miura, Koui; Sakamoto, Kiyoshi; Ueda, Ken; Baba, Rika

    2006-01-01

    We developed a cone-beam computed tomography (CBCT) system equipped with a large flat-panel detector. Data obtained by 200 o rotation imaging are reconstructed by means of CBCT to generate three-dimensional images. We report the use of CBCT angiography using CBCT in 10 patients with 8 liver malignancies and 2 hypersplenisms during abdominal interventional procedures. CBCT was very useful for interventional radiologists to confirm a perfusion area of the artery catheter wedged on CT by injection of contrast media through the catheter tip, although the image quality was slightly degraded, scoring as 2.60 on average by streak artifacts. CBCT is space-saving because it does not require a CT system with a gantry, and it is also time-saving because it does not require the transfer of patients

  12. Performance quantification of a flat-panel imager in industrial mega-voltage X-ray imaging systems

    International Nuclear Information System (INIS)

    Stritt, Carina; Plamondon, Mathieu; Hofmann, Jürgen; Flisch, Alexander; Sennhauser, Urs

    2017-01-01

    Active matrix flat-panel detectors have gained popularity amongst X-ray imaging systems due to their speed, resolution and high dynamic range. With appropriate shielding modern flat-panel imagers can even be used in high energy Computed Tomography (CT) systems of energies up to several mega-electronvolt (MeV). However, the performance of a digital detector is not independent of the rest of the radiographic system but depends on all other components of the system. Signal and noise transfer properties highly depend on all parameters of an imaging chain. This work focuses on quantifying the resolution capabilities and the noise in the signals of a MeV X-ray imaging system. The performance quantification is done by computing the modulation transfer function (MTF) using the standard edge method as well as the noise power spectrum (NPS) of the imaging system. We performed Monte Carlo (MC) simulations in order to understand the influence of scattered radiation on the measurements. A comparison of the horizontal and vertical MTF showed that the imaging behaviour of the detector is isotropic. Moreover, an additional investigation of the noise performance of the system showed that there is no measurable noise correlation present in the system. It was shown that the thickness of the edge device does not have a significant influence on the resulting system MTF. A rapid drop in the visibility could be observed resulting in a value of 1.2 line pairs per mm at 50% MTF. The visibility limit of line pair patterns was found to be at 2.3 line pairs per mm given by the 10% MTF value.

  13. Performance quantification of a flat-panel imager in industrial mega-voltage X-ray imaging systems

    Energy Technology Data Exchange (ETDEWEB)

    Stritt, Carina, E-mail: carina.stritt@empa.ch [Empa, Swiss Federal Laboratories for Material Science and Technology, Center for X-ray Analytics, Ueberlandstrasse 129, 8600 Dübendorf (Switzerland); Plamondon, Mathieu; Hofmann, Jürgen; Flisch, Alexander [Empa, Swiss Federal Laboratories for Material Science and Technology, Center for X-ray Analytics, Ueberlandstrasse 129, 8600 Dübendorf (Switzerland); Sennhauser, Urs [Empa, Swiss Federal Laboratories for Material Science and Technology, Reliability Science and Technology Laboratory, Ueberlandstrasse 129, 8600 Dübendorf (Switzerland)

    2017-03-11

    Active matrix flat-panel detectors have gained popularity amongst X-ray imaging systems due to their speed, resolution and high dynamic range. With appropriate shielding modern flat-panel imagers can even be used in high energy Computed Tomography (CT) systems of energies up to several mega-electronvolt (MeV). However, the performance of a digital detector is not independent of the rest of the radiographic system but depends on all other components of the system. Signal and noise transfer properties highly depend on all parameters of an imaging chain. This work focuses on quantifying the resolution capabilities and the noise in the signals of a MeV X-ray imaging system. The performance quantification is done by computing the modulation transfer function (MTF) using the standard edge method as well as the noise power spectrum (NPS) of the imaging system. We performed Monte Carlo (MC) simulations in order to understand the influence of scattered radiation on the measurements. A comparison of the horizontal and vertical MTF showed that the imaging behaviour of the detector is isotropic. Moreover, an additional investigation of the noise performance of the system showed that there is no measurable noise correlation present in the system. It was shown that the thickness of the edge device does not have a significant influence on the resulting system MTF. A rapid drop in the visibility could be observed resulting in a value of 1.2 line pairs per mm at 50% MTF. The visibility limit of line pair patterns was found to be at 2.3 line pairs per mm given by the 10% MTF value.

  14. Human health and ecological toxicity potentials due to heavy metal content in waste electronic devices with flat panel displays

    International Nuclear Information System (INIS)

    Lim, Seong-Rin; Schoenung, Julie M.

    2010-01-01

    Display devices such as cathode-ray tube (CRT) televisions and computer monitors are known to contain toxic substances and have consequently been banned from disposal in landfills in the State of California and elsewhere. New types of flat panel display (FPD) devices, millions of which are now purchased each year, also contain toxic substances, but have not previously been systematically studied and compared to assess the potential impact that could result from their ultimate disposal. In the current work, the focus is on the evaluation of end-of-life toxicity potential from the heavy metal content in select FPD devices with the intent to inform material selection and design-for-environment (DfE) decisions. Specifically, the metals antimony, arsenic, barium, beryllium, cadmium, chromium, cobalt, copper, lead, mercury, molybdenum, nickel, selenium, silver, vanadium, and zinc in plasma TVs, LCD (liquid crystal display) TVs, LCD computer monitors and laptop computers are considered. The human health and ecotoxicity potentials are evaluated through a life cycle assessment perspective by combining data on the respective heavy metal contents, the characterization factors in the U.S. EPA Tool for the Reduction and Assessment of Chemical and other environmental Impacts (TRACI), and a pathway and impact model. Principal contributors to the toxicity potentials are lead, arsenic, copper, and mercury. Although the heavy metal content in newer flat panel display devices creates less human health toxicity potential than that in CRTs, for ecological toxicity, the new devices are worse, especially because of the mercury in LCD TVs and the copper in plasma TVs.

  15. Robot arm based flat panel CT-guided electromagnetic tracked spine interventions: phantom and animal model experiments

    International Nuclear Information System (INIS)

    Penzkofer, Tobias; Isfort, Peter; Bruners, Philipp; Mahnken, Andreas H.; Wiemann, Christian; Guenther, Rolf W.; Kyriakou, Yiannis; Kalender, Willi A.; Schmitz-Rode, Thomas

    2010-01-01

    To evaluate accuracy and procedure times of electromagnetic tracking (EMT) in a robotic arm mounted flat panel setting using phantom and animal cadaveric models. A robotic arm mounted flat panel (RMFP) was used in combination with EMT to perform anthropomorphic phantom (n = 90) and ex vivo pig based punctures (n = 120) of lumbar facet joints (FJ, n = 120) and intervertebral discs (IVD, n = 90). Procedure accuracies and times were assessed and evaluated. FJ punctures were carried out with a spatial accuracy of 0.8 ± 0.9 mm (phantom) and 0.6 ± 0.8 mm (ex vivo) respectively. While IVD punctures showed puncture deviations of 0.6 ± 1.2 mm (phantom) and 0.5 ± 0.6 mm (ex vivo), direct and angulated phantom based punctures had accuracies of 0.8 ± 0.9 mm and 1.0 ± 1.3 mm. Planning took longer for ex vivo IVD punctures compared to phantom model interventions (39.3 ± 17.3 s vs. 20.8 ± 5.0 s, p = 0.001) and for angulated vs. direct phantom FJ punctures (19.7 ± 5.1 s vs. 28.6 ± 7.8 s, p < 0.001). Puncture times were longer for ex vivo procedures when compared to phantom model procedures in both FJ (37.9 ± 9.0 s vs. 23.6 ± 7.2 s, p = 0.001) and IVD punctures (43.9 ± 16.1 s vs. 31.1 ± 6.4 s, p = 0.026). The combination of RMFP with EMT provides an accurate method of navigation for spinal interventions such as facet joint punctures and intervertebral disc punctures. (orig.)

  16. Evaluation of imaging quality for flat-panel detector based low dose C-arm CT system

    International Nuclear Information System (INIS)

    Seo, Chang-Woo; Cha, Bo Kyung; Jeon, Sungchae; Huh, Young

    2015-01-01

    The image quality associated with the extent of the angle of gantry rotation, the number of projection views, and the dose of X-ray radiation was investigated in flat-panel detector (FPD) based C-arm cone-beam computed tomography (CBCT) system for medical applications. A prototype CBCT system for the projection acquisition used the X-ray tube (A-132, Varian inc.) having rhenium-tungsten molybdenum target and flat panel a-Si X-ray detector (PaxScan 4030CB, Varian inc.) having a 397 x 298 mm active area with 388 μm pixel pitch and 1024 x 768 pixels in 2 by 2 binning mode. The performance comparison of X-ray imaging quality was carried out using the Feldkamp, Davis, and Kress (FDK) reconstruction algorithm between different conditions of projection acquisition. In this work, head-and-dental (75 kVp/20 mA) and chest (90 kVp/25 mA) phantoms were used to evaluate the image quality. The 361 (30 fps x 12 s) projection data during 360 deg. gantry rotation with 1 deg. interval for the 3D reconstruction were acquired. Parke weighting function were applied to handle redundant data and improve the reconstructed image quality in a mobile C-arm system with limited rotation angles. The reconstructed 3D images were investigated for comparison of qualitative image quality in terms of scan protocols (projection views, rotation angles and exposure dose). Furthermore, the performance evaluation in image quality will be investigated regarding X-ray dose and limited projection data for a FPD based mobile C-arm CBCT system. (authors)

  17. Robot arm based flat panel CT-guided electromagnetic tracked spine interventions: phantom and animal model experiments

    Energy Technology Data Exchange (ETDEWEB)

    Penzkofer, Tobias; Isfort, Peter; Bruners, Philipp; Mahnken, Andreas H. [RWTH Aachen University, Applied Medical Engineering, Helmholtz-Institute Aachen, Aachen (Germany); RWTH Aachen University, Department of Diagnostic Radiology, Aachen University Hospital, Aachen (Germany); Wiemann, Christian; Guenther, Rolf W. [RWTH Aachen University, Department of Diagnostic Radiology, Aachen University Hospital, Aachen (Germany); Kyriakou, Yiannis; Kalender, Willi A. [Friedrich-Alexander University of Erlangen-Nuremberg, Institute for Medical Physics, Erlangen (Germany); Schmitz-Rode, Thomas [RWTH Aachen University, Applied Medical Engineering, Helmholtz-Institute Aachen, Aachen (Germany)

    2010-11-15

    To evaluate accuracy and procedure times of electromagnetic tracking (EMT) in a robotic arm mounted flat panel setting using phantom and animal cadaveric models. A robotic arm mounted flat panel (RMFP) was used in combination with EMT to perform anthropomorphic phantom (n = 90) and ex vivo pig based punctures (n = 120) of lumbar facet joints (FJ, n = 120) and intervertebral discs (IVD, n = 90). Procedure accuracies and times were assessed and evaluated. FJ punctures were carried out with a spatial accuracy of 0.8 {+-} 0.9 mm (phantom) and 0.6 {+-} 0.8 mm (ex vivo) respectively. While IVD punctures showed puncture deviations of 0.6 {+-} 1.2 mm (phantom) and 0.5 {+-} 0.6 mm (ex vivo), direct and angulated phantom based punctures had accuracies of 0.8 {+-} 0.9 mm and 1.0 {+-} 1.3 mm. Planning took longer for ex vivo IVD punctures compared to phantom model interventions (39.3 {+-} 17.3 s vs. 20.8 {+-} 5.0 s, p = 0.001) and for angulated vs. direct phantom FJ punctures (19.7 {+-} 5.1 s vs. 28.6 {+-} 7.8 s, p < 0.001). Puncture times were longer for ex vivo procedures when compared to phantom model procedures in both FJ (37.9 {+-} 9.0 s vs. 23.6 {+-} 7.2 s, p = 0.001) and IVD punctures (43.9 {+-} 16.1 s vs. 31.1 {+-} 6.4 s, p = 0.026). The combination of RMFP with EMT provides an accurate method of navigation for spinal interventions such as facet joint punctures and intervertebral disc punctures. (orig.)

  18. Edge-Spread Functions Expected for Several Changes in a Commercial Flat-Panel System

    International Nuclear Information System (INIS)

    Schach von Wittenau, A E

    2002-01-01

    The Bldg. 239 radiography facility uses a 9 MeV bremsstrahlung linac and a commercially available fiat-panel detector system. Ref. [1] discusses the facility in detail. Ref. [1] furthermore discusses the imaging quality of the fiat-panel system, and identifies several sources of image blur for the system in question. The maim'' contributors to the imaging blur are radiation scattered from the front cover of the detector housing, radiation scattered from the back cover of the detector housing, and radiation scattered from the aluminum plate that supports the amorphous-Si detector within the detector housing. The manufacturer of one such fiat-panel system seems willing to modify one of their products as requested, if such modifications may be made easily. Easy modifications would include making the detector housing thinner, decreasing the sizes of air gaps inside tile detector system, etc. Removing the aluminum support plate is considered to be a difficult modification. This memo reports the results of a set of Monte Carlo simulations that were performed to predict the changes in imaging quality, compared to that of the current system, if the detector is modified as suggested above. In particular, the edge-spread function (ESF) was calculated for each modification. ESFs were calculated for three photon energies: 100 keV, 450 keV, and 3 MeV. The results suggest that thinning and moving tile front and back covers of the detector housing should result in improved image quality for all of the photon energies considered. Interestingly, the results also suggest that removing the aluminum support plate would improve tim imaging performance at 100 keV and 450 keV, but that removing the plate has no additional benefit for imaging with 3 MeV photons

  19. SU-E-J-45: The Correlation Between CBCT Flat Panel Misalignment and 3D Image Guidance Accuracy

    International Nuclear Information System (INIS)

    Kenton, O; Valdes, G; Yin, L; Teo, B; Brousmiche, S; Wikler, D

    2015-01-01

    Purpose To simulate the impact of CBCT flat panel misalignment on the image quality, the calculated correction vectors in 3D image guided proton therapy and to determine if these calibration errors can be caught in our QA process. Methods The X-ray source and detector geometrical calibration (flexmap) file of the CBCT system in the AdaPTinsight software (IBA proton therapy) was edited to induce known changes in the rotational and translational calibrations of the imaging panel. Translations of up to ±10 mm in the x, y and z directions (see supplemental) and rotational errors of up to ±3° were induced. The calibration files were then used to reconstruct the CBCT image of a pancreatic patient and CatPhan phantom. Correction vectors were calculated for the patient using the software’s auto match system and compared to baseline values. The CatPhan CBCT images were used for quantitative evaluation of image quality for each type of induced error. Results Translations of 1 to 3 mm in the x and y calibration resulted in corresponding correction vector errors of equal magnitude. Similar 10mm shifts were seen in the y-direction; however, in the x-direction, the image quality was too degraded for a match. These translational errors can be identified through differences in isocenter from orthogonal kV images taken during routine QA. Errors in the z-direction had no effect on the correction vector and image quality.Rotations of the imaging panel calibration resulted in corresponding correction vector rotations of the patient images. These rotations also resulted in degraded image quality which can be identified through quantitative image quality metrics. Conclusion Misalignment of CBCT geometry can lead to incorrect translational and rotational patient correction vectors. These errors can be identified through QA of the imaging isocenter as compared to orthogonal images combined with monitoring of CBCT image quality

  20. Cone beam breast CT with a high pitch (75 μm), thick (500 μm) scintillator CMOS flat panel detector: Visibility of simulated microcalcifications

    OpenAIRE

    Shen, Youtao; Zhong, Yuncheng; Lai, Chao-Jen; Wang, Tianpeng; Shaw, Chris C.

    2013-01-01

    Purpose: To measure and investigate the improvement of microcalcification (MC) visibility in cone beam breast CT with a high pitch (75 μm), thick (500 μm) scintillator CMOS/CsI flat panel detector (Dexela 2923, Perkin Elmer).

  1. Clinical evaluation of digital angiographic system equipped with the Safire' flat-panel detector of a direct conversion type

    Energy Technology Data Exchange (ETDEWEB)

    Miura, Yoshiaki; Miura, Yusuke; Goto, Keiichi [Shimadzu Corporation, Medical Systems Division, Research and Development, Kyoto (JP)] [and others

    2003-06-01

    This report presents a report on clinical evaluation of our newly developed flat-panel X-ray detector of a direct conversion type, designed to provide images of a resolution higher than, or at least equal to, that ensured by X-ray photographic films, in clinical digital X-ray cinematography. This new detector was named 'Safire' the acronym of 'Shimadzu advanced flat imaging receptor', emphasizing its high technological level, such as the capability to ensure high quality of images. The clinical evaluation of Shimadzu DIGITEX Premier digital angiography system, equipped with this new flat-panel X-ray detector of a direct conversion type, has been started in March, 2003, at the Kokura Memorial Hospital in Kyushu, Japan. (author)

  2. Normalized noise power spectrum of full field digital mammography system

    International Nuclear Information System (INIS)

    Norriza Mohd Isa; Wan Muhamad Saridan Wan Hassan

    2009-01-01

    A method to measure noise power spectrum of a full field digital mammography system is presented. The effect of X-ray radiation dose, size and configuration of region of interest on normalized noise power spectrum (NNPS) was investigated. Flat field images were acquired using RQA-M2 beam quality technique (Mo/Mo anode-filter, 28 kV, 2 mm Al) with different clinical radiation doses. The images were cropped at about 4 cm from the edge of the breast wall and then divided into different size of non-overlapping or overlapping segments. NNPS was determined through detrending, 2-D fast Fourier transformation and normalization. Our measurement shows that high radiation dose gave lower NNPS at a specific beam quality. (Author)

  3. Normalized Noise Power Spectrum of Full Field Digital Mammography System

    International Nuclear Information System (INIS)

    Isa, Norriza Mohd; Wan Hassan, Wan Muhamad Saridan

    2010-01-01

    A method to measure noise power spectrum of a full field digital mammography system is presented. The effect of X-ray radiation dose, size and configuration of region of interest on normalized noise power spectrum (NNPS) was investigated. Flat field images were acquired using RQA-M2 beam quality technique (Mo/Mo anode-filter, 28 kV, 2 mm Al) with different clinical radiation doses. The images were cropped at about 4 cm from the edge of the breast wall and then divided into different size of non-overlapping or overlapping segments. NNPS was determined through detrending, 2-D fast Fourier transformation and normalization. Our measurement shows that high radiation dose gave lower NNPS at a specific beam quality.

  4. A compact high resolution flat panel PET detector based on the new 4-side buttable MPPC for biomedical applications.

    Science.gov (United States)

    Wang, Qiang; Wen, Jie; Ravindranath, Bosky; O'Sullivan, Andrew W; Catherall, David; Li, Ke; Wei, Shouyi; Komarov, Sergey; Tai, Yuan-Chuan

    2015-09-11

    Compact high-resolution panel detectors using virtual pinhole (VP) PET geometry can be inserted into existing clinical or pre-clinical PET systems to improve regional spatial resolution and sensitivity. Here we describe a compact panel PET detector built using the new Though Silicon Via (TSV) multi-pixel photon counters (MPPC) detector. This insert provides high spatial resolution and good timing performance for multiple bio-medical applications. Because the TSV MPPC design eliminates wire bonding and has a package dimension which is very close to the MPPC's active area, it is 4-side buttable. The custom designed MPPC array (based on Hamamatsu S12641-PA-50(x)) used in the prototype is composed of 4 × 4 TSV-MPPC cells with a 4.46 mm pitch in both directions. The detector module has 16 × 16 lutetium yttrium oxyorthosilicate (LYSO) crystal array, with each crystal measuring 0.92 × 0.92 × 3 mm 3 with 1.0 mm pitch. The outer diameter of the detector block is 16.8 × 16.8 mm 2 . Thirty-two such blocks will be arranged in a 4 × 8 array with 1 mm gaps to form a panel detector with detection area around 7 cm × 14 cm in the full-size detector. The flood histogram acquired with Ge-68 source showed excellent crystal separation capability with all 256 crystals clearly resolved. The detector module's mean, standard deviation, minimum (best) and maximum (worst) energy resolution were 10.19%, +/-0.68%, 8.36% and 13.45% FWHM, respectively. The measured coincidence time resolution between the block detector and a fast reference detector (around 200 ps single photon timing resolution) was 0.95 ns. When tested with Siemens Cardinal electronics the performance of the detector blocks remain consistent. These results demonstrate that the TSV-MPPC is a promising photon sensor for use in a flat panel PET insert composed of many high resolution compact detector modules.

  5. FY 1998 annual summary report on comprehensive development study of high-function flat panel display techniques (second year); 1998 nendo koseino flat panel display gijutsu no sogo kaihatsu kenkyu seika hokokusho. Daininendo

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-03-01

    This project is aimed at creation of the new world display industry in Shikoku by developing the high-function flat panel display techniques and thereby establishing new techniques which solve the problems involved in, e.g., LEDs, plasma-aided devices and ELs other than liquid crystal devices. For development of emitters using diamond, important results have been obtained for the morphology, and cathode luminescence, Raman and photoluminescence spectra of polycrystalline diamond, synthesized by the vapor-phase process under varying conditions, on the electron radiation characteristics of the emitters. These results have led to clarification of the optimum vapor-phase synthesis conditions for diamond for high-function emitters. The techniques utilizing focused ion beams have also advanced to develop thin polycrystalline diamond films for emitters which correspond to the image elements of quality for television. For electron emitters, a structure prepared by implantation without using a high electrical field is proposed, and the device mechanisms involved are clarified. (NEDO)

  6. Gain and offset calibration reduces variation in exposure-dependent SNR among systems with identical digital flat-panel detectors.

    Science.gov (United States)

    Willis, Charles E; Vinogradskiy, Yevgeniy Y; Lofton, Brad K; White, R Allen

    2011-07-01

    The conditions under which vendor performance criteria for digital radiography systems are obtained do not adequately simulate the conditions of actual clinical imaging with respect to radiographic technique factors, scatter production, and scatter control. Therefore, the relationship between performance under ideal conditions and performance in clinical practice remains unclear. Using data from a large complement of systems in clinical use, the authors sought to develop a method to establish expected performance criteria for digital flat-panel radiography systems with respect to signal-to-noise ratio (SNR) versus detector exposure under clinical conditions for thoracic imaging. The authors made radiographic exposures of a patient-equivalent chest phantom at 125 kVp and 180 cm source-to-image distance. The mAs value was modified to produce exposures above and below the mAs delivered by automatic exposure control. Exposures measured free-in-air were corrected to the imaging plane by the inverse square law, by the attenuation factor of the phantom, and by the Bucky factor of the grid for the phantom, geometry, and kilovolt peak. SNR was evaluated as the ratio of the mean to the standard deviation (SD) of a region of interest automatically selected in the center of each unprocessed image. Data were acquired from 18 systems, 14 of which were tested both before and after gain and offset calibration. SNR as a function of detector exposure was interpolated using a double logarithmic function to stratify the data into groups of 0.2, 0.5, 1.0, 2.0, and 5.0 mR exposure (1.8, 4.5, 9.0, 18, and 45 microGy air KERMA) to the detector. The mean SNR at each exposure interval after calibration exhibited linear dependence on the mean SNR before calibration (r2=0.9999). The dependence was greater than unity (m = 1.101 +/- 0.006), and the difference from unity was statistically significant (p grid replacement. The nonconformant behavior of the other system was corrected by replacing

  7. Robot arm based flat panel CT-guided electromagnetic tracked spine interventions: phantom and animal model experiments.

    Science.gov (United States)

    Penzkofer, Tobias; Isfort, Peter; Bruners, Philipp; Wiemann, Christian; Kyriakou, Yiannis; Kalender, Willi A; Günther, Rolf W; Schmitz-Rode, Thomas; Mahnken, Andreas H

    2010-11-01

    To evaluate accuracy and procedure times of electromagnetic tracking (EMT) in a robotic arm mounted flat panel setting using phantom and animal cadaveric models. A robotic arm mounted flat panel (RMFP) was used in combination with EMT to perform anthropomorphic phantom (n = 90) and ex vivo pig based punctures (n = 120) of lumbar facet joints (FJ, n = 120) and intervertebral discs (IVD, n = 90). Procedure accuracies and times were assessed and evaluated. FJ punctures were carried out with a spatial accuracy of 0.8 ± 0.9 mm (phantom) and 0.6 ± 0.8 mm (ex vivo) respectively. While IVD punctures showed puncture deviations of 0.6 ± 1.2 mm (phantom) and 0.5 ± 0.6 mm (ex vivo), direct and angulated phantom based punctures had accuracies of 0.8 ± 0.9 mm and 1.0 ± 1.3 mm. Planning took longer for ex vivo IVD punctures compared to phantom model interventions (39.3 ± 17.3 s vs. 20.8 ± 5.0 s, p = 0.001) and for angulated vs. direct phantom FJ punctures (19.7 ± 5.1 s vs. 28.6 ± 7.8 s, p < 0.001). Puncture times were longer for ex vivo procedures when compared to phantom model procedures in both FJ (37.9 ± 9.0 s vs. 23.6 ± 7.2 s, p = 0.001) and IVD punctures (43.9 ± 16.1 s vs. 31.1 ± 6.4 s, p = 0.026). The combination of RMFP with EMT provides an accurate method of navigation for spinal interventions such as facet joint punctures and intervertebral disc punctures.

  8. Noise, sampling, and the number of projections in cone-beam CT with a flat-panel detector

    International Nuclear Information System (INIS)

    Zhao, Z.; Gang, G. J.; Siewerdsen, J. H.

    2014-01-01

    Purpose: To investigate the effect of the number of projection views on image noise in cone-beam CT (CBCT) with a flat-panel detector. Methods: This fairly fundamental consideration in CBCT system design and operation was addressed experimentally (using a phantom presenting a uniform medium as well as statistically motivated “clutter”) and theoretically (using a cascaded systems model describing CBCT noise) to elucidate the contributing factors of quantum noise (σ Q ), electronic noise (σ E ), and view aliasing (σ view ). Analysis included investigation of the noise, noise-power spectrum, and modulation transfer function as a function of the number of projections (N proj ), dose (D tot ), and voxel size (b vox ). Results: The results reveal a nonmonotonic relationship between image noise andN proj at fixed total dose: for the CBCT system considered, noise decreased with increasing N proj due to reduction of view sampling effects in the regime N proj proj due to increased electronic noise. View sampling effects were shown to depend on the heterogeneity of the object in a direct analytical relationship to power-law anatomical clutter of the form κ/f  β —and a general model of individual noise components (σ Q , σ E , and σ view ) demonstrated agreement with measurements over a broad range in N proj , D tot , and b vox . Conclusions: The work elucidates fairly basic elements of CBCT noise in a manner that demonstrates the role of distinct noise components (viz., quantum, electronic, and view sampling noise). For configurations fairly typical of CBCT with a flat-panel detector (FPD), the analysis reveals a “sweet spot” (i.e., minimum noise) in the rangeN proj ∼ 250–350, nearly an order of magnitude lower in N proj than typical of multidetector CT, owing to the relatively high electronic noise in FPDs. The analysis explicitly relates view aliasing and quantum noise in a manner that includes aspects of the object (“clutter”) and imaging chain

  9. Comparison of imaging properties of direct-type and indirect-type of flat-panel detector

    International Nuclear Information System (INIS)

    Matsumoto, Masao; Suekane, Koji; Ichimaru, Yasunobu; Ogata, Yuji; Inamura, Kiyonari; Kanai, Kouzou; Kanamori, Hitoshi

    2002-01-01

    A Flat-Panel Detector (FPD) has many advantages such as eliminating cassette handling and being able to display a preview image immediately in addition to the digital image processing and the networking. Thus, the FPD has ability to innovate the radiology department. We measured and evaluated the digital and over-all imaging properties (characteristic curves, modulation Transfer Functions, Wiener spectra and Noise Equivalent Quanta (NEQ) for the direct-type and indirect-type of FPD. The pre-sampling and overall NEQ of the indirect-type of FPD were better than the NEQ of the direct-type of FPD at lower spatial frequencies, but were worse at higher spatial frequencies. The FPD can take image data at real-time and be easy to digitalize. From these results, Screen/Film system and Computed Radiography system will be replaced by the FPD system, together with diffusion of CAD, cone beam Computed Tomography (CT) system and open-type Magnetic Resonance Imagining (MRI) system. (T. Tanaka)

  10. Method of estimating patient skin dose from dose displayed on medical X-ray equipment with flat panel detector

    International Nuclear Information System (INIS)

    Fukuda, Atsushi; Koshida, Kichiro; Togashi, Atsuhiko; Matsubara, Kousuke

    2004-01-01

    The International Electrotechnical Commission (IEC) has stipulated that medical X-ray equipment for interventional procedures must display radiation doses such as air kerma in free air at the interventional reference point and dose area product to establish radiation safety for patients (IEC 60601-2-43). However, it is necessary to estimate entrance skin dose for the patient from air kerma for an accurate risk assessment of radiation skin injury. To estimate entrance skin dose from displayed air kerma in free air at the interventional reference point, it is necessary to consider effective energy, the ratio of the mass-energy absorption coefficient for skin and air, and the backscatter factor. In addition, since automatic exposure control is installed in medical X-ray equipment with flat panel detectors, it is necessary to know the characteristics of control to estimate exposure dose. In order to calculate entrance skin dose under various conditions, we investigated clinical parameters such as tube voltage, tube current, pulse width, additional filter, and focal spot size, as functions of patient body size. We also measured the effective energy of X-ray exposure for the patient as a function of clinical parameter settings. We found that the conversion factor from air kerma in free air to entrance skin dose is about 1.4 for protection. (author)

  11. Development of CT and 3D-CT Using Flat Panel Detector Based Real-Time Digital Radiography System

    International Nuclear Information System (INIS)

    Ravindran, V. R.; Sreelakshmi, C.; Vibin

    2008-01-01

    The application of Digital Radiography in the Nondestructive Evaluation (NDE) of space vehicle components is a recent development in India. A Real-time DR system based on amorphous silicon Flat Panel Detector has been developed for the NDE of solid rocket motors at Rocket Propellant Plant of VSSC in a few years back. The technique has been successfully established for the nondestructive evaluation of solid rocket motors. The DR images recorded for a few solid rocket specimens are presented in the paper. The Real-time DR system is capable of generating sufficient digital X-ray image data with object rotation for the CT image reconstruction. In this paper the indigenous development of CT imaging based on the Realtime DR system for solid rocket motor is presented. Studies are also carried out to generate 3D-CT image from a set of adjacent CT images of the rocket motor. The capability of revealing the spatial location and characterisation of defect is demonstrated by the CT and 3D-CT images generated.

  12. C-arm flat-panel CT arthrography of the shoulder: Radiation dose considerations and preliminary data on diagnostic performance

    Energy Technology Data Exchange (ETDEWEB)

    Guggenberger, Roman; Ulbrich, Erika J.; Kaelin, Pascal; Pfammatter, Thomas; Alkadhi, Hatem; Andreisek, Gustav [University Hospital Zurich, Institute of Diagnostic and Interventional Radiology, Zuerich (Switzerland); Dietrich, Tobias J. [Balgrist University Hospital, Department of Radiology, Zurich (Switzerland); Scholz, Rosemarie; Koehler, Christoph; Elsaesser, Thilo [Siemens Healthcare GmbH, Business Area Advanced Therapies, Forchheim (Germany); Le Corroller, Thomas [Aix-Marseille Universite, CNRS, ISM UMR 7287, Marseille (France); Radiology Department, APHM, Marseille (France)

    2017-02-15

    To investigate radiation dose and diagnostic performance of C-arm flat-panel CT (FPCT) versus standard multi-detector CT (MDCT) shoulder arthrography using MRI-arthrography as reference standard. Radiation dose of two different FPCT acquisitions (5 and 20 s) and standard MDCT of the shoulder were assessed using phantoms and thermoluminescence dosimetry. FPCT arthrographies were performed in 34 patients (mean age 44 ± 15 years). Different joint structures were quantitatively and qualitatively assessed by two independent radiologists. Inter-reader agreement and diagnostic performance were calculated. Effective radiation dose was markedly lower in FPCT 5 s (0.6 mSv) compared to MDCT (1.7 mSv) and FPCT 20 s (3.4 mSv). Contrast-to-noise ratios (CNRs) were significantly (p < 0.05) higher in FPCT 20-s versus 5-s protocols. Inter-reader agreements of qualitative ratings ranged between κ = 0.47-1.0. Sensitivities for cartilage and rotator cuff pathologies were low for FPCT 5-s (40 % and 20 %) and moderate for FPCT 20-s protocols (75 % and 73 %). FPCT showed high sensitivity (81-86 % and 89-99 %) for bone and acromioclavicular-joint pathologies. Using a 5-s protocol FPCT shoulder arthrography provides lower radiation dose compared to MDCT but poor sensitivity for cartilage and rotator cuff pathologies. FPCT 20-s protocol is moderately sensitive for cartilage and rotator cuff tendon pathology with markedly higher radiation dose compared to MDCT. (orig.)

  13. High-resolution dynamic angiography using flat-panel volume CT: feasibility demonstration for neuro and lower limb vascular applications

    International Nuclear Information System (INIS)

    Mehndiratta, Amit; Rabinov, James D.; Grasruck, Michael; Liao, Eric C.; Crandell, David; Gupta, Rajiv

    2015-01-01

    This paper evaluates a prototype flat-panel volume CT (fpVCT) for dynamic in vivo imaging in a variety of neurovascular and lower limb applications. Dynamic CTA was performed on 12 patients (neuro = 8, lower limb = 4) using an fpVCT with 120 kVp, 50 mA, rotation time varying from 8 to 19 s, and field of view of 25 x 25 x 18 cm 3 . Four-dimensional data sets (i.e. 3D images over time) were reconstructed and reviewed. Dynamic CTA demonstrated sufficient spatio-temporal resolution to elucidate first-pass and recirculation dynamics of contrast bolus through neurovasclar pathologies and phasic blood flow though lower-limb vasculature and grafts. The high spatial resolution of fpVCT resulted in reduced partial volume and metal beam-hardening artefacts. This facilitated assessment of vascular lumen in the presence of calcified plaque and evaluation of fractures, especially in the presence of fixation hardware. Evaluation of arteriovenous malformation using dynamic fpVCT angiography was of limited utility. Dynamic CTA using fpVCT can visualize time-varying phenomena in neuro and lower limb vascular applications and has sufficient diagnostic imaging quality to evaluate a number of pathologies affecting these regions. (orig.)

  14. Characteristics and applications of a flat panel computer tomography system; Eigenschaften und Anwendungen der Flaechendetektor-basierten Volumen-Computertomographie

    Energy Technology Data Exchange (ETDEWEB)

    Knollmann, F.; Valencia, R.; Obenauer, S. [Abt. Diagnostische Radiologie, Klinikum der Georg-August-Univ. Goettingen (Germany); Buhk, J.H. [Abt. Neuroradiologie, Univ. Goettingen (Germany)

    2006-09-15

    Purpose: to assess a new flat panel volume computed tomography (FP-VCT) with very high isotropic spatial resolution as well as high Z-axis coverage. Materials and Methods: The prototype of an FP-VCT scanner with a detector cell size of 0.2 mm was used for numerous phantom studies, specimen examinations, and animal research projects. Results: The high spatial resolution of the new system can be used to accurately determine solid tumor volume, thus allowing for earlier assessment of the therapeutic response. In animal experimentation, whole-body perfusion mapping of mice is feasible. The high spatial resolution also improves the classification of coronary artery atherosclerotic plaques in the isolated post mortem human heart. With the depiction of intramyocardial segments of the coronary arteries, investigations of myocardial collateral circulation are feasible. In skeletal applications, an accurate analysis of the smallest bony structures, e.g., petrous bone and dental preparations, can be successfully performed, as well as investigations of repetitive studies of fracture healing and the treatment of osteoporosis. Conclusion: The introduction of FP-VCT opens up new applications for CT, including the field of molecular imaging, which are highly attractive for future clinical applications. Present limitations include limited temporal resolution and necessitate further improvement of the system. (orig.)

  15. Cross Talk Study to the Single Photon Response of a Flat Panel PMT for the RICH Upgrade at LHCb

    CERN Multimedia

    Arnaboldi, C; Calvi, M; Fanchini, E; Gotti, C; Maino, M; Matteuzzi, C; Perego, D L; Pessina, G; Wang, J C

    2009-01-01

    The Ring Imaging CHerenkov, RICH, detector at LHCb is now readout by Hybrid Photon Detectors. In view of its upgrade a possible option is the adoption of the flat panel Photon Multipliers Tubes, PMT. An important issue for the good determination of the rings produced in the sensitive media is a negligible level of cross talk. We have experimentally studied the cross talk from the 64x64 pixels of the H9500 PMT from Hamamatsu. Results have shown that at the single photon signal level, as expected at LHCb, the statistics applied to the small number of electrons generated at the first dynode of the PMT chain leads to a cross talk mechanism that must be interpreted in term of the percentage of the number of induced signals rather than on the amplitude of the induced signals. The threshold to suppress cross talk must be increased to a significant fraction of the single photon signal for the worst case. The number of electrons generated at the first dynode is proportional to the biasing voltage. Measurements have sh...

  16. C-arm flat-panel CT arthrography of the shoulder: Radiation dose considerations and preliminary data on diagnostic performance

    International Nuclear Information System (INIS)

    Guggenberger, Roman; Ulbrich, Erika J.; Kaelin, Pascal; Pfammatter, Thomas; Alkadhi, Hatem; Andreisek, Gustav; Dietrich, Tobias J.; Scholz, Rosemarie; Koehler, Christoph; Elsaesser, Thilo; Le Corroller, Thomas

    2017-01-01

    To investigate radiation dose and diagnostic performance of C-arm flat-panel CT (FPCT) versus standard multi-detector CT (MDCT) shoulder arthrography using MRI-arthrography as reference standard. Radiation dose of two different FPCT acquisitions (5 and 20 s) and standard MDCT of the shoulder were assessed using phantoms and thermoluminescence dosimetry. FPCT arthrographies were performed in 34 patients (mean age 44 ± 15 years). Different joint structures were quantitatively and qualitatively assessed by two independent radiologists. Inter-reader agreement and diagnostic performance were calculated. Effective radiation dose was markedly lower in FPCT 5 s (0.6 mSv) compared to MDCT (1.7 mSv) and FPCT 20 s (3.4 mSv). Contrast-to-noise ratios (CNRs) were significantly (p < 0.05) higher in FPCT 20-s versus 5-s protocols. Inter-reader agreements of qualitative ratings ranged between κ = 0.47-1.0. Sensitivities for cartilage and rotator cuff pathologies were low for FPCT 5-s (40 % and 20 %) and moderate for FPCT 20-s protocols (75 % and 73 %). FPCT showed high sensitivity (81-86 % and 89-99 %) for bone and acromioclavicular-joint pathologies. Using a 5-s protocol FPCT shoulder arthrography provides lower radiation dose compared to MDCT but poor sensitivity for cartilage and rotator cuff pathologies. FPCT 20-s protocol is moderately sensitive for cartilage and rotator cuff tendon pathology with markedly higher radiation dose compared to MDCT. (orig.)

  17. Aging of imaging properties of a CMOS flat-panel detector for dental cone-beam computed tomography

    Science.gov (United States)

    Kim, D. W.; Han, J. C.; Yun, S.; Kim, H. K.

    2017-01-01

    We have experimentally investigated the long-term stability of imaging properties of a flat-panel detector in conditions used for dental x-ray imaging. The detector consists of a CsI:Tl layer and CMOS photodiode pixel arrays. Aging simulations were carried out using an 80-kVp x-ray beam at an air-kerma rate of approximately 5 mGy s-1 at the entrance surface of the detector with a total air kerma of up to 0.6 kGy. Dark and flood-field images were periodically obtained during irradiation, and the mean signal and noise levels were evaluated for each image. We also evaluated the modulation-transfer function (MTF), noise-power spectrum (NPS), and detective quantum efficiency (DQE). The aging simulation showed a decrease in both the signal and noise of the gain-offset-corrected images, but there was negligible change in the signal-to-noise performance as a function of the accumulated dose. The gain-offset correction for analyzing images resulted in negligible changes in MTF, NPS, and DQE results over the total dose. Continuous x-ray exposure to a detector can cause degradation in the physical performance factors such the detector sensitivity, but linear analysis of the gain-offset-corrected images can assure integrity of the imaging properties of a detector during its lifetime.

  18. High-resolution dynamic angiography using flat-panel volume CT: feasibility demonstration for neuro and lower limb vascular applications

    Energy Technology Data Exchange (ETDEWEB)

    Mehndiratta, Amit [Massachusetts General Hospital, Department of Radiology, Harvard Medical School, Boston, MA (United States); University of Oxford, Institute of Biomedical Engineering and Keble College, Oxford (United Kingdom); Indian Institute of Technology Delhi and All India Institute of Medical Science, Centre for Biomedical Engineering, New Delhi (India); Rabinov, James D. [Massachusetts General Hospital, Interventional Neuroradiology, Harvard Medical School, Boston, MA (United States); Grasruck, Michael [Siemens Medical Solutions, Forchheim (Germany); Liao, Eric C. [Massachusetts General Hospital, Department of Plastic and Reconstructive Surgery and Center for Regenerative Medicine, Harvard Medical School, Boston, MA (United States); Crandell, David [Spaulding Rehabilitation Hospital, Department of Physical Medicine and Rehabilitation, Harvard Medical School, Charlestown, MA (United States); Gupta, Rajiv [Massachusetts General Hospital, Department of Radiology, Harvard Medical School, Boston, MA (United States)

    2015-07-15

    This paper evaluates a prototype flat-panel volume CT (fpVCT) for dynamic in vivo imaging in a variety of neurovascular and lower limb applications. Dynamic CTA was performed on 12 patients (neuro = 8, lower limb = 4) using an fpVCT with 120 kVp, 50 mA, rotation time varying from 8 to 19 s, and field of view of 25 x 25 x 18 cm{sup 3}. Four-dimensional data sets (i.e. 3D images over time) were reconstructed and reviewed. Dynamic CTA demonstrated sufficient spatio-temporal resolution to elucidate first-pass and recirculation dynamics of contrast bolus through neurovasclar pathologies and phasic blood flow though lower-limb vasculature and grafts. The high spatial resolution of fpVCT resulted in reduced partial volume and metal beam-hardening artefacts. This facilitated assessment of vascular lumen in the presence of calcified plaque and evaluation of fractures, especially in the presence of fixation hardware. Evaluation of arteriovenous malformation using dynamic fpVCT angiography was of limited utility. Dynamic CTA using fpVCT can visualize time-varying phenomena in neuro and lower limb vascular applications and has sufficient diagnostic imaging quality to evaluate a number of pathologies affecting these regions. (orig.)

  19. Embedded nonvolatile memory devices with various silicon nitride energy band gaps on glass used for flat panel display applications

    International Nuclear Information System (INIS)

    Son, Dang Ngoc; Van Duy, Nguyen; Jung, Sungwook; Yi, Junsin

    2010-01-01

    Nonvolatile memory (NVM) devices with a nitride–nitride–oxynitride stack structure on a rough poly-silicon (poly-Si) surface were fabricated using a low-temperature poly-Si (LTPS) thin film transistor technology on glass substrates for application of flat panel display (FPD). The plasma-assisted oxidation/nitridation method is used to form a uniform oxynitride with an ultrathin tunneling layer on a rough LTPS surface. The NVMs, using a Si-rich silicon nitride film as a charge-trapping layer, were proposed as one of the solutions for the improvement of device performance such as the program/erase speed, the memory window and the charge retention characteristics. To further improve the vertical scaling and charge retention characteristics of NVM devices, the high-κ high-density N-rich SiN x films are used as a blocking layer. The fabricated NVM devices have outstanding electrical properties, such as a low threshold voltage, a high ON/OFF current ratio, a low subthreshold swing, a low operating voltage of less than ±9 V and a large memory window of 3.7 V, which remained about 1.9 V over a period of 10 years. These characteristics are suitable for electrical switching and data storage with in FPD application

  20. The effect of dose reduction on image quality in digital radiography using a flat-panel detector: experimental study in rabbits

    International Nuclear Information System (INIS)

    Jung, Sung Il; Goo, Jin Mo; Lee, Hyun Ju; Moon, Woo Kyung; Lim, Kun Young; Cho, Gyung Goo; Kim, Ji Hoon; Im, Jung Gi; Choi, Jang Yong; Nam, Sang Hee

    2005-01-01

    To evaluate the effect of dose reduction on image quality in digital radiography using a flat-panel detector. Digital radiographs of 30 rabbits were obtained at two different dose levels (33.23 μGY for the standard dose group and 20.09 μGY for the reduced dose group). The amorphous selenium-based flat-panel detector system had a panel size of 7 x 8.5 inches, a matrix of 1280 x 1536 (pixels?), and a pixel pitch of 138 μm. Four observers evaluated the soft-copy images on a high-resolution video monitor (2560 x 2048 x 8 bits) in random order. The observers rated the visibility of 13 different anatomic structures on a 5-point scale, viz, the retrocardiac lung, subdiaphragmatic lung, heart border, diaphragmatic border, proximal airway, unobscured lung, liver border, kidney border, bowel gas, flank stripe, ribs, and vertebrae in the mediastinal and abdominal regions. Statistical significance was determined using Wilcoxon's signed rank test. There was no statistically significant difference in the visibility of the anatomic structures on digital radiography between the standard and reduced dose groups. Digital radiography using an amorphous selenium-based flat-panel detector can preserve the image quality, though the dose is reduced to 40% of the standard level

  1. The effect of dose reduction on image quality in digital radiography using a flat-panel detector: experimental study in rabbits

    Energy Technology Data Exchange (ETDEWEB)

    Jung, Sung Il; Goo, Jin Mo; Lee, Hyun Ju; Moon, Woo Kyung; Lim, Kun Young; Cho, Gyung Goo; Kim, Ji Hoon; Im, Jung Gi [Seoul National College of Medicine, Seoul (Korea, Republic of); Choi, Jang Yong; Nam, Sang Hee [Inje University, Seoul (Korea, Republic of)

    2005-07-15

    To evaluate the effect of dose reduction on image quality in digital radiography using a flat-panel detector. Digital radiographs of 30 rabbits were obtained at two different dose levels (33.23 {mu}GY for the standard dose group and 20.09 {mu}GY for the reduced dose group). The amorphous selenium-based flat-panel detector system had a panel size of 7 x 8.5 inches, a matrix of 1280 x 1536 (pixels?), and a pixel pitch of 138 {mu}m. Four observers evaluated the soft-copy images on a high-resolution video monitor (2560 x 2048 x 8 bits) in random order. The observers rated the visibility of 13 different anatomic structures on a 5-point scale, viz, the retrocardiac lung, subdiaphragmatic lung, heart border, diaphragmatic border, proximal airway, unobscured lung, liver border, kidney border, bowel gas, flank stripe, ribs, and vertebrae in the mediastinal and abdominal regions. Statistical significance was determined using Wilcoxon's signed rank test. There was no statistically significant difference in the visibility of the anatomic structures on digital radiography between the standard and reduced dose groups. Digital radiography using an amorphous selenium-based flat-panel detector can preserve the image quality, though the dose is reduced to 40% of the standard level.

  2. Digital chest radiography with an amorphous silicon flat-panel-detector versus a storage-phosphor system: comparison of soft-copy images

    International Nuclear Information System (INIS)

    Lee, Hyun Ju; Im, Jung Gi; Goo, Jin Mo; Lee, Chang Hyun

    2006-01-01

    We compared the soft-copy images produced by an amorphous silicon flat-panel-detector system with the images produced by a storage-phosphor radiography system for their ability to visualize anatomic regions of the chest. Two chest radiologists independently analyzed 234 posteroanterior chest radiographs obtained from 78 patients on high-resolution liquid crystal display monitors (2560 x 2048 x 8 bits). In each patient, one radiograph was obtained with a storage-phosphor system, and two radiographs were obtained via amorphous silicon flat-panel-detector radiography with and without spatial frequency filtering. After randomizing the 234 images, the interpreters rated the visibility and radiographic quality of 11 different anatomic regions. Each image was ranked on a five-point scale (1 = not visualized, 2 = poor visualization, 3 = fair visualization, 4 = good visualization, and 5 = excellent visualization). The statistical difference between each system was determined using the Wilcoxon's signed rank test. The visibility of three anatomic regions (hilum, heart border and ribs), as determined by the chest radiologist with 14 years experience (ρ < 0.05) and the visibility of the thoracic spine, as determined by the chest radiologist with 8 years experience (ρ = 0.036), on the amorphous silicon flat-panel-detector radiography prior to spatial frequency filtering were significantly superior to that on the storage-phosphor radiography. The visibility of 11 anatomic regions, as determined by the chest radiologist with 14 years experience (ρ < 0.0001) and the visibility of five anatomic regions (unobscured lung, rib, proximal airway, thoracic spine and overall appearance), as determined by the chest radiologist with 8 years experience (ρ < 0.05), on the amorphous silicon flat-panel-detector radiography after spatial frequency filtering were significantly superior to that on the storage-phosphor radiography. The amorphous silicon flat-panel-detector system depicted the

  3. TU-F-18C-02: Increasing Amorphous Selenium Thickness in Direct Conversion Flat-Panel Imagers for Contrast-Enhanced Dual-Energy Breast Imaging

    International Nuclear Information System (INIS)

    Scaduto, DA; Hu, Y-H; Zhao, W

    2014-01-01

    Purpose: Contrast-enhanced (CE) breast imaging using iodinated contrast agents requires imaging with x-ray spectra at energies greater than those used in mammography. Optimizing amorphous selenium (a-Se) flat panel imagers (FPI) for this higher energy range may increase lesion conspicuity. Methods: We compare imaging performance of a conventional FPI with 200 μm a-Se conversion layer to a prototype FPI with 300 μm a-Se layer. Both detectors are evaluated in a Siemens MAMMOMAT Inspiration prototype digital breast tomosynthesis (DBT) system using low-energy (W/Rh 28 kVp) and high-energy (W/Cu 49 kVp) x-ray spectra. Detectability of iodinated lesions in dual-energy images is evaluated using an iodine contrast phantom. Effects of beam obliquity are investigated in projection and reconstructed images using different reconstruction methods. The ideal observer signal-to-noise ratio is used as a figure-of-merit to predict the optimal a-Se thickness for CE lesion detectability without compromising conventional full-field digital mammography (FFDM) and DBT performance. Results: Increasing a-Se thickness from 200 μm to 300 μm preserves imaging performance at typical mammographic energies (e.g. W/Rh 28 kVp), and improves the detective quantum efficiency (DQE) for high energy (W/Cu 49 kVp) by 30%. While the more penetrating high-energy x-ray photons increase geometric blur due to beam obliquity in the FPI with thicker a-Se layer, the effect on lesion detectability in FBP reconstructions is negligible due to the reconstruction filters employed. Ideal observer SNR for CE objects shows improvements in in-plane detectability with increasing a-Se thicknesses, though small lesion detectability begins to degrade in oblique projections for a-Se thickness above 500 μm. Conclusion: Increasing a-Se thickness in direct conversion FPI from 200 μm to 300 μm improves lesion detectability in CE breast imaging with virtually no cost to conventional FFDM and DBT. This work was partially

  4. Use and imaging performance of CMOS flat panel imager with LiF/ZnS(Ag) and Gadox scintillation screens for neutron radiography

    Science.gov (United States)

    Cha, B. K.; kim, J. Y.; Kim, T. J.; Sim, C.; Cho, G.; Lee, D. H.; Seo, C.-W.; Jeon, S.; Huh, Y.

    2011-01-01

    In digital neutron radiography system, a thermal neutron imaging detector based on neutron-sensitive scintillating screens with CMOS(complementary metal oxide semiconductor) flat panel imager is introduced for non-destructive testing (NDT) application. Recently, large area CMOS APS (active-pixel sensor) in conjunction with scintillation films has been widely used in many digital X-ray imaging applications. Instead of typical imaging detectors such as image plates, cooled-CCD cameras and amorphous silicon flat panel detectors in combination with scintillation screens, we tried to apply a scintillator-based CMOS APS to neutron imaging detection systems for high resolution neutron radiography. In this work, two major Gd2O2S:Tb and 6LiF/ZnS:Ag scintillation screens with various thickness were fabricated by a screen printing method. These neutron converter screens consist of a dispersion of Gd2O2S:Tb and 6LiF/ZnS:Ag scintillating particles in acrylic binder. These scintillating screens coupled-CMOS flat panel imager with 25x50mm2 active area and 48μm pixel pitch was used for neutron radiography. Thermal neutron flux with 6x106n/cm2/s was utilized at the NRF facility of HANARO in KAERI. The neutron imaging characterization of the used detector was investigated in terms of relative light output, linearity and spatial resolution in detail. The experimental results of scintillating screen-based CMOS flat panel detectors demonstrate possibility of high sensitive and high spatial resolution imaging in neutron radiography system.

  5. Digital radiography with a large-scale electronic flat-panel detector vs screen-film radiography: observer preference in clinical skeletal diagnostics

    International Nuclear Information System (INIS)

    Hamers, S.; Freyschmidt, J.; Neitzel, U.

    2001-01-01

    The imaging performance of a recently developed digital flat-panel detector system was compared with conventional screen-film imaging in an observer preference study. In total, 34 image pairs of various regions of the skeleton were obtained in 24 patients; 30 image pairs were included in the study. The conventional images were acquired with 250- and 400-speed screen-film combinations, using the standard technique of our department. Within hours, the digital images were obtained using identical exposure parameters. The digital system employed a large-area (43 x 43 cm) flat-panel detector based on amorphous silicon (Trixell Pixium 4600), integrated in a Bucky table. Six radiologists independently evaluated the image pairs with respect to image latitude, soft tissue rendition, rendition of the periosteal and enosteal border of cortical bone, rendition of cancellous bone and the visibility of potentially present pathological changes, using a subjective five-point scale. The digital images were rated significantly (p=0.001) better than the screen-film images with respect to soft tissue rendition and image latitude. Also the rendition of the cancellous bone and the periosteal and enosteal border of the cortical bone was rated significantly (p=0.05) better for the flat-panel detector. The visibility of pathological lesions was equivalent; only large-area sclerotic lesions (n=2) were seen superiorly on screen-film images. The new digital flat-panel detector based on amorphous silicon appears to be at least equivalent to conventional screen-film combinations for skeletal examinations, and in most respects even superior. (orig.)

  6. A performance comparison of flat-panel imager-based MV and kV cone-beam CT

    International Nuclear Information System (INIS)

    Groh, B.A.; Siewerdsen, J.H.; Drake, D.G.; Wong, J.W.; Jaffray, D.A.

    2002-01-01

    The use of cone-beam computed tomography (CBCT) has been proposed for guiding the delivery of radiation therapy, and investigators have examined the use of both kilovoltage (kV) and megavoltage (MV) x-ray beams in the development of such CBCT systems. In this paper, the inherent contrast and signal-to-noise ratio (SNR) performance for a variety of existing and hypothetical detectors for CBCT are investigated analytically as a function of imaging dose and object size. Theoretical predictions are compared to the results of experimental investigations employing large-area flat-panel imagers (FPIs) at kV and MV energies. Measurements were performed on two different FPI-based CBCT systems: a bench-top prototype incorporating an FPI and kV x-ray source (100 kVp x rays), and a system incorporating an FPI mounted on the gantry of a medical linear accelerator (6 MV x rays). The SNR in volume reconstructions was measured as a function of dose and found to agree reasonably with theoretical predictions. These results confirm the theoretically predicted advantages of employing kV energy x rays in imaging soft-tissue structures found in the human body. While MV CBCT may provide a valuable means of correcting 3D setup errors and may offer an advantage in terms of simplicity of mechanical integration with a linear accelerator (e.g., implementation in place of a portal imager), kV CBCT offers significant performance advantages in terms of image contrast and SNR per unit dose for visualization of soft-tissue structures. The relatively poor SNR performance at MV energies is primarily a result of the low x-ray quantum efficiencies (∼a few percent or less) that are currently achieved with FPIs at high energies. Furthermore, kV CBCT with an FPI offers the potential of combined volumetric and radiographic/fluoroscopic imaging using the same device

  7. Cone-beam CT with a flat-panel detector: From image science to image-guided surgery

    International Nuclear Information System (INIS)

    Siewerdsen, Jeffrey H.

    2011-01-01

    The development of large-area flat-panel X-ray detectors (FPDs) has spurred investigation in a spectrum of advanced medical imaging applications, including tomosynthesis and cone-beam CT (CBCT). Recent research has extended image quality metrics and theoretical models to such applications, providing a quantitative foundation for the assessment of imaging performance as well as a general framework for the design, optimization, and translation of such technologies to new applications. For example, cascaded systems models of the Fourier domain metrics, such as noise-equivalent quanta (NEQ), have been extended to these modalities to describe the propagation of signal and noise through the image acquisition and reconstruction chain and to quantify the factors that govern spatial resolution, image noise, and detectability. Moreover, such models have demonstrated basic agreement with human observer performance for a broad range of imaging conditions and imaging tasks. These developments in image science have formed a foundation for the knowledgeable development and translation of CBCT to new applications in image-guided interventions-for example, CBCT implemented on a mobile surgical C-arm for intraoperative 3D imaging. The ability to acquire high-quality 3D images on demand during surgical intervention overcomes conventional limitations of surgical guidance in the context of preoperative images alone. A prototype mobile C-arm developed in academic-industry partnership demonstrates CBCT with low radiation dose, sub-mm spatial resolution, and soft-tissue visibility potentially approaching that of diagnostic CT. Integration of the 3D imaging system with real-time tracking, deformable registration, endoscopic video, and 3D visualization offers a promising addition to the surgical arsenal in interventions ranging from head-and-neck/skull base surgery to spine, orthopaedic, thoracic, and abdominal surgeries. Cadaver studies show the potential for significant boosts in surgical

  8. Percutaneous sacroplasty with the use of C-arm flat-panel detector CT: technical feasibility and clinical outcome

    International Nuclear Information System (INIS)

    Kang, Sung Eun; Lee, Joon Woo; Kim, Joo Hyung; Kang, Heung Sik; Park, Kun Woo; Yeom, Jin S.

    2011-01-01

    Sacroplasty for sacral insufficiency fractures (SIFs) has been performed mostly under computed tomography (CT) or fluoroscopy guidance. The purposes of this study are to describe technical tips and clinical outcomes of sacroplasty under C-arm flat panel detector CT (C-arm CT) guidance, and to compare the cement distributions shown on C-arm CT with those on multi-detector CT (MDCT). This study consisted of patients who underwent sacroplasty for SIF using C-arm CT from May 2006 to May 2009. Technical success was assessed in terms of cement filling and leakage. Clinical outcome was assessed at short-term (less than 1 month) and long-term (more than 1 month) follow-up using a four-grade patient satisfaction scale: poor, fair, good, and excellent. After sacroplasty, all patients underwent MDCT and three radiologists compared MDCT images with C-arm CT images in consensus, focusing on the cement distribution and cement leakage. Sacroplasties were performed on both sacral alae in all 8 patients (male:female = 2:6, mean age = 76.9, range = 63-82). The technical success rate was 100%. At short-term follow up, 6 patients (87.5%) reported significant improvement. Five patients (62.5%) were available for long-term follow-up and all 5 patients reported a reduced pain and an improved ability to ambulate. Using MDCT as the standard of reference, the cement distribution was visualized equally well by C-arm CT. Sacroplasty under C-arm CT showed excellent technical success and good clinical outcome. There was an excellent correlation between C-arm CT and MDCT in evaluating cement distribution and cement leakage. (orig.)

  9. Percutaneous sacroplasty with the use of C-arm flat-panel detector CT: technical feasibility and clinical outcome

    Energy Technology Data Exchange (ETDEWEB)

    Kang, Sung Eun; Lee, Joon Woo; Kim, Joo Hyung; Kang, Heung Sik [Seoul National University Bundang Hospital, Department of Radiology, Gyeonggi-do (Korea, Republic of); Park, Kun Woo; Yeom, Jin S. [Seoul National University Bundang Hospital, Department of Orthopaedic Surgery, Gyeonggi-do (Korea, Republic of)

    2011-04-15

    Sacroplasty for sacral insufficiency fractures (SIFs) has been performed mostly under computed tomography (CT) or fluoroscopy guidance. The purposes of this study are to describe technical tips and clinical outcomes of sacroplasty under C-arm flat panel detector CT (C-arm CT) guidance, and to compare the cement distributions shown on C-arm CT with those on multi-detector CT (MDCT). This study consisted of patients who underwent sacroplasty for SIF using C-arm CT from May 2006 to May 2009. Technical success was assessed in terms of cement filling and leakage. Clinical outcome was assessed at short-term (less than 1 month) and long-term (more than 1 month) follow-up using a four-grade patient satisfaction scale: poor, fair, good, and excellent. After sacroplasty, all patients underwent MDCT and three radiologists compared MDCT images with C-arm CT images in consensus, focusing on the cement distribution and cement leakage. Sacroplasties were performed on both sacral alae in all 8 patients (male:female = 2:6, mean age = 76.9, range = 63-82). The technical success rate was 100%. At short-term follow up, 6 patients (87.5%) reported significant improvement. Five patients (62.5%) were available for long-term follow-up and all 5 patients reported a reduced pain and an improved ability to ambulate. Using MDCT as the standard of reference, the cement distribution was visualized equally well by C-arm CT. Sacroplasty under C-arm CT showed excellent technical success and good clinical outcome. There was an excellent correlation between C-arm CT and MDCT in evaluating cement distribution and cement leakage. (orig.)

  10. Cone-beam CT with a flat-panel detector: From image science to image-guided surgery

    Energy Technology Data Exchange (ETDEWEB)

    Siewerdsen, Jeffrey H., E-mail: jeff.siewerdsen@jhu.edu [Department of Biomedical Engineering, Johns Hopkins University, Traylor Building, Room 718, 720 Rutland Avenue, Baltimore, MD 21205 (United States)

    2011-08-21

    The development of large-area flat-panel X-ray detectors (FPDs) has spurred investigation in a spectrum of advanced medical imaging applications, including tomosynthesis and cone-beam CT (CBCT). Recent research has extended image quality metrics and theoretical models to such applications, providing a quantitative foundation for the assessment of imaging performance as well as a general framework for the design, optimization, and translation of such technologies to new applications. For example, cascaded systems models of the Fourier domain metrics, such as noise-equivalent quanta (NEQ), have been extended to these modalities to describe the propagation of signal and noise through the image acquisition and reconstruction chain and to quantify the factors that govern spatial resolution, image noise, and detectability. Moreover, such models have demonstrated basic agreement with human observer performance for a broad range of imaging conditions and imaging tasks. These developments in image science have formed a foundation for the knowledgeable development and translation of CBCT to new applications in image-guided interventions-for example, CBCT implemented on a mobile surgical C-arm for intraoperative 3D imaging. The ability to acquire high-quality 3D images on demand during surgical intervention overcomes conventional limitations of surgical guidance in the context of preoperative images alone. A prototype mobile C-arm developed in academic-industry partnership demonstrates CBCT with low radiation dose, sub-mm spatial resolution, and soft-tissue visibility potentially approaching that of diagnostic CT. Integration of the 3D imaging system with real-time tracking, deformable registration, endoscopic video, and 3D visualization offers a promising addition to the surgical arsenal in interventions ranging from head-and-neck/skull base surgery to spine, orthopaedic, thoracic, and abdominal surgeries. Cadaver studies show the potential for significant boosts in surgical

  11. Semi-automatic classification of skeletal morphology in genetically altered mice using flat-panel volume computed tomography.

    Directory of Open Access Journals (Sweden)

    Christian Dullin

    2007-07-01

    Full Text Available Rapid progress in exploring the human and mouse genome has resulted in the generation of a multitude of mouse models to study gene functions in their biological context. However, effective screening methods that allow rapid noninvasive phenotyping of transgenic and knockout mice are still lacking. To identify murine models with bone alterations in vivo, we used flat-panel volume computed tomography (fpVCT for high-resolution 3-D imaging and developed an algorithm with a computational intelligence system. First, we tested the accuracy and reliability of this approach by imaging discoidin domain receptor 2- (DDR2- deficient mice, which display distinct skull abnormalities as shown by comparative landmark-based analysis. High-contrast fpVCT data of the skull with 200 microm isotropic resolution and 8-s scan time allowed segmentation and computation of significant shape features as well as visualization of morphological differences. The application of a trained artificial neuronal network to these datasets permitted a semi-automatic and highly accurate phenotype classification of DDR2-deficient compared to C57BL/6 wild-type mice. Even heterozygous DDR2 mice with only subtle phenotypic alterations were correctly determined by fpVCT imaging and identified as a new class. In addition, we successfully applied the algorithm to classify knockout mice lacking the DDR1 gene with no apparent skull deformities. Thus, this new method seems to be a potential tool to identify novel mouse phenotypes with skull changes from transgenic and knockout mice on the basis of random mutagenesis as well as from genetic models. However for this purpose, new neuronal networks have to be created and trained. In summary, the combination of fpVCT images with artificial neuronal networks provides a reliable, novel method for rapid, cost-effective, and noninvasive primary screening tool to detect skeletal phenotypes in mice.

  12. Novel Na(+) doped Alq3 hybrid materials for organic light-emitting diode (OLED) devices and flat panel displays.

    Science.gov (United States)

    Bhagat, S A; Borghate, S V; Kalyani, N Thejo; Dhoble, S J

    2015-05-01

    Pure and Na(+) -doped Alq3 complexes were synthesized by a simple precipitation method at room temperature, maintaining a stoichiometric ratio. These complexes were characterized by X-ray diffraction, Fourier transform infrared (FTIR), UV/Vis absorption and photoluminescence (PL) spectra. The X-ray diffractogram exhibits well-resolved peaks, revealing the crystalline nature of the synthesized complexes, FTIR confirms the molecular structure and the completion of quinoline ring formation in the metal complex. UV/Vis absorption and PL spectra of sodium-doped Alq3 complexes exhibit high emission intensity in comparison with Alq3 phosphor, proving that when doped in Alq3 , Na(+) enhances PL emission intensity. The excitation spectra of the synthesized complexes lie in the range 242-457 nm when weak shoulders are also considered. Because the sharp excitation peak falls in the blue region of visible radiation, the complexes can be employed for blue chip excitation. The emission wavelength of all the synthesized complexes lies in the bluish green/green region ranging between 485 and 531 nm. The intensity of the emission wavelength was found to be elevated when Na(+) is doped into Alq3 . Because both the excitation and emission wavelengths fall in the visible region of electromagnetic radiation, these phosphors can also be employed to improve the power conversion efficiency of photovoltaic cells by using the solar spectral conversion principle. Thus, the synthesized phosphors can be used as bluish green/green light-emitting phosphors for organic light-emitting diodes, flat panel displays, solid-state lighting technology - a step towards the desire to reduce energy consumption and generate pollution free light. Copyright © 2014 John Wiley & Sons, Ltd.

  13. Optimization of dual-energy subtraction chest radiography by use of a direct-conversion flat-panel detector system.

    Science.gov (United States)

    Fukao, Mari; Kawamoto, Kiyosumi; Matsuzawa, Hiroaki; Honda, Osamu; Iwaki, Takeshi; Doi, Tsukasa

    2015-01-01

    We aimed to optimize the exposure conditions in the acquisition of soft-tissue images using dual-energy subtraction chest radiography with a direct-conversion flat-panel detector system. Two separate chest images were acquired at high- and low-energy exposures with standard or thick chest phantoms. The high-energy exposure was fixed at 120 kVp with the use of an auto-exposure control technique. For the low-energy exposure, the tube voltages and entrance surface doses ranged 40-80 kVp and 20-100 % of the dose required for high-energy exposure, respectively. Further, a repetitive processing algorithm was used for reduction of the image noise generated by the subtraction process. Seven radiology technicians ranked soft-tissue images, and these results were analyzed using the normalized-rank method. Images acquired at 60 kVp were of acceptable quality regardless of the entrance surface dose and phantom size. Using a repetitive processing algorithm, the minimum acceptable doses were reduced from 75 to 40 % for the standard phantom and to 50 % for the thick phantom. We determined that the optimum low-energy exposure was 60 kVp at 50 % of the dose required for the high-energy exposure. This allowed the simultaneous acquisition of standard radiographs and soft-tissue images at 1.5 times the dose required for a standard radiograph, which is significantly lower than the values reported previously.

  14. Flat-panel detector volumetric CT for visualization of subarachnoid hemorrhage and ventricles: preliminary results compared to conventional CT

    International Nuclear Information System (INIS)

    Doelken, M.; Struffert, T.; Richter, G.; Engelhorn, T.; Doerfler, A.; Nimsky, C.; Ganslandt, O.; Hammen, T.

    2008-01-01

    The aim of this study was to compare flat-panel volumetric CT (VCT) to conventional CT (cCT) in the visualization of the extent of subarachnoid hemorrhage (SAH) and the width of the ventricles in patients with acute SAH. Included in the study were 22 patients with an acutely ruptured cerebral aneurysm who received VCT during coil embolization. VCT image quality, the extent of SAH (using a modified Fisher score and total slice number with SAH visible) and the width of the ventricles (Evans index) were evaluated by two experienced neuroradiologists (RAD1 and RAD2) and compared to the findings on cCT. Ten patients undergoing VCT for reasons other than SAH served as negative controls. Interobserver agreement in rating image quality was excellent for cCT (Kendall W value 0.94) and good for VCT (0.74). SAH was identified by RAD1 and RAD2 on VCT images in all patients. The modified Fisher scores underestimated the extent of SAH on VCT images in comparison with cCT images. Pearson's correlation coefficient (r) regarding the number of image slices with SAH visible on cCT images compared with the number on VCT images was 0.85 for RAD1 and 0.84 for RAD2. The r value for the degree of interobserver agreement for the number of slices with SAH visible was 0.99 for cCT, and 0.95 for VCT images (n 19), respectively. The width of the ventricles measured in terms of the Evans Index showed excellent concordance between the modalities (r = 0.81 vs. 0.82). Our preliminary results indicate that VCT is helpful in evaluating SAH in the angiography suite. Additionally, reliable evaluation of ventricle width is feasible. However, there are limitations with regard to the visibility of SAH on VCT images in comparison to cCT images. (orig.)

  15. A new system for fully automatic inspection of digital flat-panel detector radiographs of aluminium castings

    International Nuclear Information System (INIS)

    Fuchs, T.; Hassler, U.; Huetten, U.; Wenzel, T.

    2006-01-01

    The aim of our work was the integration of various newly-developed methods into a system for fully automatic radioscopic inspection of arbitrary casting parts. Using a 16-bit flat-panel detector, projections in arbitrary directions through the part are acquired and analysed. The software tool for inspection can be separated into five stages: registration, calibration, image processing, fault segmentation, and quality assessment. Thereby, each step is realized with full 16-bit data processing. Within the first processing stage, information about the physical length and density of the aluminium structures is extracted from the primary projections. Next, the primary image is registered with a reference image, which was acquired previously. Afterwards, the third stage combines both reference image-based and reference-less testing. A filter is applied, which adapts automatically to the local object structure by referring to the properties of the reference. Thereby, the self-adapting filter selects its size, direction and filter method optimally according to the local situation. Similar to the reference-less procedure, a subtraction is followed by a threshold operation, resulting in a map of regions that are suspected to be faulty. The fourth step aims at an elimination of false-positive detections. Again, two methods are applied successively: evaluation of local image features at suspicious positions and a classification based on teachings independent of position and orientation of the faults. Within the last step the quality criteria are applied. These criteria may concern fault size and depth, the density of faults in critical regions and a minimum distance between two or more faults. (orig.)

  16. Evaluation the image obtained from X-ray flat-panel detectors utilizing a polycrystalline CdZnTe film as the conversion layer

    International Nuclear Information System (INIS)

    Tokuda, S.; Kishihara, H.; Kaino, M.; Sato, T.

    2006-01-01

    We can expect that fluoroscopic images with a high sensitivity and excellent detective efficiency can be obtained by using a semiconductor with a small W factor for the conversion layer of X-ray flat-panel detectors, which have experienced a rapid gain inpopularity for medical and non-destructive industrial inspection uses in recent years. We believe that polycrystalline CdZnTe film formed by the closed spaced sublimation (CSS) method is a promising conversion material for next-generation high efficiency X-ray flat-panel detectors, and have previously reported the results of feasibility studies. In this paper, we present an overview of X-ray flat-panel detectors and the features of CdZnTe film, then we describe the CSS method of deposition and evaluation of the physical characteristics of CdZnTe film, and finally we present the results of our fabrication and testing of proto-type detectors utilizing CdZnTe film. (author)

  17. Flat-Panel Computed Tomography (DYNA-CT) in Neuroradiology. From High-Resolution Imaging of Implants to One-Stop-Shopping for Acute Stroke.

    Science.gov (United States)

    Doerfler, A; Gölitz, P; Engelhorn, T; Kloska, S; Struffert, T

    2015-10-01

    Originally aimed at improving standard radiography by providing higher absorption efficiency and a wider dynamic range, flat-panel detector technology has meanwhile got widely accepted in the neuroradiological community. Especially flat-panel detector computed tomography (FD-CT) using rotational C-arm mounted flat-panel detector technology is capable of volumetric imaging with a high spatial resolution. By providing CT-like images of the brain within the angio suite, FD-CT is able to rapidly visualize hemorrhage and may thus improve complication management without the need of patient transfer. As "Angiographic CT" FD-CT may be helpful during many diagnostic and neurointerventional procedures and for noninvasive monitoring and follow-up. In addition, spinal interventions and high-resolution imaging of the temporal bone might also benefit from FD-CT. Finally, using novel dynamic perfusion and angiographic protocols, FD-CT may provide functional information on brain perfusion and vasculature with the potential to replace standard imaging in selected acute stroke patients.

  18. X-ray performance of a wafer-scale CMOS flat panel imager for applications in medical imaging and nondestructive testing

    International Nuclear Information System (INIS)

    Cha, Bo Kyung; Jeon, Seongchae; Seo, Chang-Woo

    2016-01-01

    This paper presents a wafer-scale complementary metal-oxide semiconductor (CMOS)-based X-ray flat panel detector for medical imaging and nondestructive testing applications. In this study, our proposed X-ray CMOS flat panel imager has been fabricated by using a 0.35 µm 1-poly/4-metal CMOS process. The pixel size is 100 µm×100 µm and the pixel array format is 1200×1200 pixels, which provide a field-of-view (FOV) of 120mm×120 mm. The 14.3-bit extended counting analog-to digital converter (ADC) with built-in binning mode was used to reduce the area and simultaneously improve the image resolution. The different screens such as thallium-doped CsI (CsI:Tl) and terbium gadolinium oxysulfide (Gd_2O_2S:Tb) scintillators were used as conversion materials for X-rays to visible light photons. The X-ray imaging performance such as X-ray sensitivity as a function of X-ray exposure dose, spatial resolution, image lag and X-ray images of various objects were measured under practical medical and industrial application conditions. This paper results demonstrate that our prototype CMOS-based X-ray flat panel imager has the significant potential for medical imaging and non-destructive testing (NDT) applications with high-resolution and high speed rate.

  19. A true minimally invasive approach for cochlear implantation: high accuracy in cranial base navigation through flat-panel-based volume computed tomography.

    Science.gov (United States)

    Majdani, Omid; Bartling, Soenke H; Leinung, Martin; Stöver, Timo; Lenarz, Minoo; Dullin, Christian; Lenarz, Thomas

    2008-02-01

    High-precision intraoperative navigation using high-resolution flat-panel volume computed tomography makes feasible the possibility of minimally invasive cochlear implant surgery, including cochleostomy. Conventional cochlear implant surgery is typically performed via mastoidectomy with facial recess to identify and avoid damage to vital anatomic landmarks. To accomplish this procedure via a minimally invasive approach--without performing mastoidectomy--in a precise fashion, image-guided technology is necessary. With such an approach, surgical time and expertise may be reduced, and hearing preservation may be improved. Flat-panel volume computed tomography was used to scan 4 human temporal bones. A drilling channel was planned preoperatively from the mastoid surface to the round window niche, providing a margin of safety to all functional important structures (e.g., facial nerve, chorda tympani, incus). Postoperatively, computed tomographic imaging and conventional surgical exploration of the drilled route to the cochlea were performed. All 4 specimens showed a cochleostomy located at the scala tympani anterior inferior to the round window. The chorda tympani was damaged in 1 specimen--this was preoperatively planned as a narrow facial recess was encountered. Using flat-panel volume computed tomography for image-guided surgical navigation, we were able to perform minimally invasive cochlear implant surgery defined as a narrow, single-channel mastoidotomy with cochleostomy. Although this finding is preliminary, it is technologically achievable.

  20. X-ray performance of a wafer-scale CMOS flat panel imager for applications in medical imaging and nondestructive testing

    Energy Technology Data Exchange (ETDEWEB)

    Cha, Bo Kyung, E-mail: goldrain99@kaist.ac.kr [Advanced Medical Device Research Center, Korea Electrotechnology Research Institute, Ansan (Korea, Republic of); Jeon, Seongchae [Advanced Medical Device Research Center, Korea Electrotechnology Research Institute, Ansan (Korea, Republic of); Seo, Chang-Woo [Department of Radiological Science, Yonsei University, Gangwon-do 220-710 (Korea, Republic of)

    2016-09-21

    This paper presents a wafer-scale complementary metal-oxide semiconductor (CMOS)-based X-ray flat panel detector for medical imaging and nondestructive testing applications. In this study, our proposed X-ray CMOS flat panel imager has been fabricated by using a 0.35 µm 1-poly/4-metal CMOS process. The pixel size is 100 µm×100 µm and the pixel array format is 1200×1200 pixels, which provide a field-of-view (FOV) of 120mm×120 mm. The 14.3-bit extended counting analog-to digital converter (ADC) with built-in binning mode was used to reduce the area and simultaneously improve the image resolution. The different screens such as thallium-doped CsI (CsI:Tl) and terbium gadolinium oxysulfide (Gd{sub 2}O{sub 2}S:Tb) scintillators were used as conversion materials for X-rays to visible light photons. The X-ray imaging performance such as X-ray sensitivity as a function of X-ray exposure dose, spatial resolution, image lag and X-ray images of various objects were measured under practical medical and industrial application conditions. This paper results demonstrate that our prototype CMOS-based X-ray flat panel imager has the significant potential for medical imaging and non-destructive testing (NDT) applications with high-resolution and high speed rate.

  1. Quantitative image quality evaluation of pixel-binning in a flat-panel detector for x-ray fluoroscopy

    International Nuclear Information System (INIS)

    Srinivas, Yogesh; Wilson, David L.

    2004-01-01

    X-ray fluoroscopy places stringent design requirements on new flat-panel (FP) detectors, requiring both low-noise electronics and high data transfer rates. Pixel-binning, wherein data from more that one detector pixel are collected simultaneously, not only lowers the data transfer rate but also increases x-ray counts and pixel signal-to-noise ratio (SNR). In this study, we quantitatively assessed image quality of image sequences from four acquisition methods; no-binning and three types of binning; in synthetic images using a clinically relevant task of detecting an extended guidewire in a four-alternative forced-choice paradigm. Binning methods were conventional data-line (D) and gate-line (G) binning, and a novel method in which alternate frames in an image sequence used D and G binning. Two detector orientations placed the data lines either parallel or perpendicular to the guide wire. At a low exposure of 0.6 μR (1.548x10 -10 C/kg) per frame, irrespective of detector orientation, D binning with its reduced electronic noise was significantly (p -10 C/kg) per frame, with data lines parallel to the guidewire, detection with D binning was significantly (p<0.1) better than G binning. However, with data lines perpendicular to the guidewire, G binning was significantly (p<0.1) better than D binning because the partial area effect was reduced. Alternate binning was the best binning method when results were averaged over both orientations, and it was as good as the best binning method at either orientation. In addition, at low and high exposures, alternate binning gave a temporally fused image with a smooth guidewire, an important image quality feature not assessed in a detection experiment. While at high exposure, detection with no binning was as good, or better, than the best binning method, it might be impractical at fluoroscopy imaging rates. A computational observer model based on signal detection theory successfully fit data and was used to predict effects of

  2. Extra-oral dental radiography for disaster victims using a flat panel X-ray detector and a hand-held X-ray generator.

    Science.gov (United States)

    Ohtani, M; Oshima, T; Mimasaka, S

    2017-12-01

    Forensic odontologists commonly incise the skin for post-mortem dental examinations when it is difficult to open the victim's mouth. However, it is prohibited by law to incise dead bodies without permission in Japan. Therefore, we attempted using extra-oral dental radiography, using a digital X-ray equipment with rechargeable batteries, to overcome this restriction. A phantom was placed in the prone position on a table, and three plain dental radiographs were used per case: "lateral oblique radiographs" for left and right posterior teeth and a "contact radiograph" for anterior teeth were taken using a flat panel X-ray detector and a hand-held X-ray generator. The resolving power of the images was measured by a resolution test chart, and the scattered X-ray dose was measured using an ionization chamber-type survey meter. The resolving power of the flat panel X-ray detector was 3.0 lp/mm, which was less than that of intra-oral dental methods, but the three extra-oral plain dental radiographs provided the overall dental information from outside of the mouth, and this approach was less time-consuming. In addition, the higher dose of scattered X-rays was laterally distributed, but the dose per case was much less than that of intra-oral dental radiographs. Extra-oral plain dental radiography can be used for disaster victim identification by dental methods even when it is difficult to open the mouth. Portable and rechargeable devices, such as a flat panel X-ray detector and a hand-held X-ray generator, are convenient to bring and use anywhere, even at a disaster scene lacking electricity and water.

  3. Metallic artifacts from internal scaphoid fracture fixation screws: comparison between C-arm flat-panel, cone-beam, and multidetector computed tomography.

    Science.gov (United States)

    Finkenstaedt, Tim; Morsbach, Fabian; Calcagni, Maurizio; Vich, Magdalena; Pfirrmann, Christian W A; Alkadhi, Hatem; Runge, Val M; Andreisek, Gustav; Guggenberger, Roman

    2014-08-01

    The aim of this study was to compare image quality and extent of artifacts from scaphoid fracture fixation screws using different computed tomography (CT) modalities and radiation dose protocols. Imaging of 6 cadaveric wrists with artificial scaphoid fractures and different fixation screws was performed in 2 screw positions (45° and 90° orientation in relation to the x/y-axis) using multidetector CT (MDCT) and 2 flat-panel CT modalities, C-arm flat-panel CT (FPCT) and cone-beam CT (CBCT), the latter 2 with low and standard radiation dose protocols. Mean cartilage attenuation and metal artifact-induced absolute Hounsfield unit changes (= artifact extent) were measured. Two independent radiologists evaluated different image quality criteria using a 5-point Likert-scale. Interreader agreements (Cohen κ) were calculated. Mean absolute Hounsfield unit changes and quality ratings were compared using Friedman and Wilcoxon signed-rank tests. Artifact extent was significantly smaller for MDCT and standard-dose FPCT compared with CBCT low- and standard-dose acquisitions (all P 0.05). Both MDCT and FPCT standard-dose protocols showed equal ratings for screw bone interface, fracture line, and trabecular bone evaluation (P = 0.06, 0.2, and 0.2, respectively) and performed significantly better than FPCT low- and CBCT low- and standard-dose acquisitions (all P < 0.05). Good interreader agreement was found for image quality comparisons (Cohen κ = 0.76-0.78). Both MDCT and FPCT standard-dose acquisition showed comparatively less metal-induced artifacts and better overall image quality compared with FPCT low-dose and both CBCT acquisitions. Flat-panel CT may provide sufficient image quality to serve as a versatile CT alternative for postoperative imaging of internally fixated wrist fractures.

  4. Dual-energy cone-beam CT with a flat-panel detector: Effect of reconstruction algorithm on material classification

    International Nuclear Information System (INIS)

    Zbijewski, W.; Gang, G. J.; Xu, J.; Wang, A. S.; Stayman, J. W.; Taguchi, K.; Carrino, J. A.; Siewerdsen, J. H.

    2014-01-01

    Purpose: Cone-beam CT (CBCT) with a flat-panel detector (FPD) is finding application in areas such as breast and musculoskeletal imaging, where dual-energy (DE) capabilities offer potential benefit. The authors investigate the accuracy of material classification in DE CBCT using filtered backprojection (FBP) and penalized likelihood (PL) reconstruction and optimize contrast-enhanced DE CBCT of the joints as a function of dose, material concentration, and detail size. Methods: Phantoms consisting of a 15 cm diameter water cylinder with solid calcium inserts (50–200 mg/ml, 3–28.4 mm diameter) and solid iodine inserts (2–10 mg/ml, 3–28.4 mm diameter), as well as a cadaveric knee with intra-articular injection of iodine were imaged on a CBCT bench with a Varian 4343 FPD. The low energy (LE) beam was 70 kVp (+0.2 mm Cu), and the high energy (HE) beam was 120 kVp (+0.2 mm Cu, +0.5 mm Ag). Total dose (LE+HE) was varied from 3.1 to 15.6 mGy with equal dose allocation. Image-based DE classification involved a nearest distance classifier in the space of LE versus HE attenuation values. Recognizing the differences in noise between LE and HE beams, the LE and HE data were differentially filtered (in FBP) or regularized (in PL). Both a quadratic (PLQ) and a total-variation penalty (PLTV) were investigated for PL. The performance of DE CBCT material discrimination was quantified in terms of voxelwise specificity, sensitivity, and accuracy. Results: Noise in the HE image was primarily responsible for classification errors within the contrast inserts, whereas noise in the LE image mainly influenced classification in the surrounding water. For inserts of diameter 28.4 mm, DE CBCT reconstructions were optimized to maximize the total combined accuracy across the range of calcium and iodine concentrations, yielding values of ∼88% for FBP and PLQ, and ∼95% for PLTV at 3.1 mGy total dose, increasing to ∼95% for FBP and PLQ, and ∼98% for PLTV at 15.6 mGy total dose. For a

  5. Performance Study of an aSi Flat Panel Detector for Fast Neutron Imaging of Nuclear Waste

    Energy Technology Data Exchange (ETDEWEB)

    Schumann, M.; Mauerhofer, E. [Institute of Energy and Climate Research - Nuclear Waste Management and Reactor Safety, Forschungszentrum Juelich GmbH, 52425 Juelich (Germany); Engels, R.; Kemmerling, G. [Central Institute for Engineering, Electronics and Analytics - Electronic Systems, Forschungszentrum Juelich GmbH, 52425 Juelich (Germany); Frank, M. [MATHCCES - Department of Mathematics, RWTH Aachen University, 52062 Aachen (Germany); Havenith, A.; Kettler, J.; Klapdor-Kleingrothaus, T. [Institute of Nuclear Engineering and Technology Transfer, RWTH Aachen University, 52062 Aachen (Germany); Schitthelm, O. [Corporate Technology, Siemens AG, 91058 Erlangen (Germany)

    2015-07-01

    Radioactive waste must be characterized to check its conformance for intermediate storage and final disposal according to national regulations. For the determination of radio-toxic and chemo-toxic contents of radioactive waste packages non-destructive analytical techniques are preferentially used. Fast neutron imaging is a promising technique to assay large and dense items providing, in complementarity to photon imaging, additional information on the presence of structures in radioactive waste packages. Therefore the feasibility of a compact Neutron Imaging System for Radioactive waste Analysis (NISRA) using 14 MeV neutrons is studied in a cooperation framework of Forschungszentrum Juelich GmbH, RWTH Aachen University and Siemens AG. However due to the low neutron emission of neutron generators in comparison to research reactors the challenging task resides in the development of an imaging detector with a high efficiency, a low sensitivity to gamma radiation and a resolution sufficient for the purpose. The setup is composed of a commercial D-T neutron generator (Genie16GT, Sodern) with a surrounding shielding made of polyethylene, which acts as a collimator and an amorphous silicon flat panel detector (aSi, 40 x 40 cm{sup 2}, XRD-1642, Perkin Elmer). Neutron detection is achieved using a general propose plastic scintillator (EJ-260, Eljen Technology) linked to the detector. The thermal noise of the photodiodes is reduced by employing an entrance window made of aluminium. Optimal gain and integration time for data acquisition are set by measuring the response of the detector to the radiation of a 500 MBq {sup 241}Am-source. Detector performance was studied by recording neutron radiography images of materials with various, but well known, chemical compositions, densities and dimensions (Al, C, Fe, Pb, W, concrete, polyethylene, 5 x 8 x 10 cm{sup 3}). To simulate gamma-ray emitting waste radiographs in presence of a gamma-ray sources ({sup 60}Co, {sup 137}Cs, {sup 241

  6. Prototype of a flat-panel photoreactor using TiO2 nanoparticles coated on transparent granules for the degradation of Methylene Blue under solar illumination

    Directory of Open Access Journals (Sweden)

    Sutisna

    2017-07-01

    Full Text Available The purpose of this work is to design a prototype of a flat-panel (FP photoreactor for wastewater treatment via solar illumination using TiO2 nano-photocatalysts. The TiO2 nanoparticles are initially coated on transparent plastic granules to avoid the difficulties associated with the recovery of nanoparticles after completing the treatment process. The coated granules were distributed in the space inside the reactor panel. The upper cover of the reactor is a transparent material that allows light penetration to activate the catalyst. Wastewater is circulated into the spaces between the coated granules. When exposed to solar illumination, photocatalytic reactions occur on nearly the entire surface of the coated granules. To test the reactor viability, we used technical grade TiO2 (for affordability and a solution of Methylene Blue (MB as a sample of wastewater. The photoreactor was tested for treating 30 L of MB solution with an initial concentration of 25 mg L−1. We observed that the reactor was able to degrade more than 98% of the MB in the solution after 48 h of solar illumination. The performance of the FP photoreactor was also improved by arranging several reactor panels in series. Using four panels, we observed that the complete decomposition of the same MB solution can be achieved within 10 h. The proposed FP photoreactor is a very promising alternative for use in decomposing recalcitrant organic pollutants in wastewater.

  7. High-quality 3D correction of ring and radiant artifacts in flat panel detector-based cone beam volume CT imaging

    Science.gov (United States)

    Abu Anas, Emran Mohammad; Kim, Jae Gon; Lee, Soo Yeol; Kamrul Hasan, Md

    2011-10-01

    The use of an x-ray flat panel detector is increasingly becoming popular in 3D cone beam volume CT machines. Due to the deficient semiconductor array manufacturing process, the cone beam projection data are often corrupted by different types of abnormalities, which cause severe ring and radiant artifacts in a cone beam reconstruction image, and as a result, the diagnostic image quality is degraded. In this paper, a novel technique is presented for the correction of error in the 2D cone beam projections due to abnormalities often observed in 2D x-ray flat panel detectors. Template images are derived from the responses of the detector pixels using their statistical properties and then an effective non-causal derivative-based detection algorithm in 2D space is presented for the detection of defective and mis-calibrated detector elements separately. An image inpainting-based 3D correction scheme is proposed for the estimation of responses of defective detector elements, and the responses of the mis-calibrated detector elements are corrected using the normalization technique. For real-time implementation, a simplification of the proposed off-line method is also suggested. Finally, the proposed algorithms are tested using different real cone beam volume CT images and the experimental results demonstrate that the proposed methods can effectively remove ring and radiant artifacts from cone beam volume CT images compared to other reported techniques in the literature.

  8. Metal artifact reduction for flat panel detector intravenous CT angiography in patients with intracranial metallic implants after endovascular and surgical treatment.

    Science.gov (United States)

    Pjontek, Rastislav; Önenköprülü, Belgin; Scholz, Bernhard; Kyriakou, Yiannis; Schubert, Gerrit A; Nikoubashman, Omid; Othman, Ahmed; Wiesmann, Martin; Brockmann, Marc A

    2016-08-01

    Flat panel detector CT angiography with intravenous contrast agent injection (IV CTA) allows high-resolution imaging of cerebrovascular structures. Artifacts caused by metallic implants like platinum coils or clips lead to degradation of image quality and are a significant problem. To evaluate the influence of a prototype metal artifact reduction (MAR) algorithm on image quality in patients with intracranial metallic implants. Flat panel detector CT after intravenous application of 80 mL contrast agent was performed with an angiography system (Artis zee; Siemens, Forchheim, Germany) using a 20 s rotation protocol (200° rotation angle, 20 s acquisition time, 496 projections). The data before and after MAR of 26 patients with a total of 34 implants (coils, clips, stents) were independently evaluated by two blinded neuroradiologists. MAR improved the assessability of the brain parenchyma and small vessels (diameter metallic implants and at a distance of 6 cm (p<0.001 each, Wilcoxon test). Furthermore, MAR significantly improved the assessability of parent vessel patency and potential aneurysm remnants (p<0.005 each, McNemar test). MAR, however, did not improve assessability of stented vessels. When an intravenous contrast protocol is used, MAR significantly ameliorates the assessability of brain parenchyma, vessels, and treated aneurysms in patients with intracranial coils or clips. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/

  9. Preliminary performance of image quality for a low-dose C-arm CT system with a flat-panel detector

    Energy Technology Data Exchange (ETDEWEB)

    Kyung Cha, Bo [Advanced Medical Device Research Center, Korea Electrotechnology Research Institute, Ansan (Korea, Republic of); Seo, Chang-Woo [Department of Radiation Convergence Engineering, College of Health Science, Yonsei University, Wonju (Korea, Republic of); Yang, Keedong [Advanced Medical Device Research Center, Korea Electrotechnology Research Institute, Ansan (Korea, Republic of); Jeon, Seongchae, E-mail: sarim@keri.re.kr [Advanced Medical Device Research Center, Korea Electrotechnology Research Institute, Ansan (Korea, Republic of); Huh, Young [Advanced Medical Device Research Center, Korea Electrotechnology Research Institute, Ansan (Korea, Republic of)

    2015-06-01

    Digital flat panel imager (FPI)-based cone-beam computed tomography (CBCT) has been widely used in C-arm imaging for spine surgery and interventional procedures. The system provides real-time fluoroscopy with high spatial resolution and three-dimensional (3D) visualization of anatomical structure without the need for patient transportation in interventional suite. In this work, a prototype CBCT imaging platform with continuous single rotation about the gantry was developed by using a large-area flat-panel detector with amorphous Si-based thin film transistor matrix. The different 2D projection images were acquired during constant gantry velocity for reconstructed images at a tube voltage of 80–120 kVp, and different current (10–50 mA) conditions. Various scan protocols were applied to a chest phantom human by changing the number of projection images and scanning angles. The projections were then reconstructed into a volumetric data of sections by using a 3D reconstruction algorithm (e.g., filtered back projection). The preliminary quantitative X-ray performance of our CBCT system was investigated by using the American Association of Physicists in Medicine CT phantom in terms of spatial resolution, contrast resolution, and CT number linearity for mobile or fixed C-arm based CBCT application with limited rotational geometry. The novel results of the projection data with different scanning angles and angular increments in the orbital gantry platform were acquired and evaluated experimentally.

  10. Preliminary performance of image quality for a low-dose C-arm CT system with a flat-panel detector

    International Nuclear Information System (INIS)

    Kyung Cha, Bo; Seo, Chang-Woo; Yang, Keedong; Jeon, Seongchae; Huh, Young

    2015-01-01

    Digital flat panel imager (FPI)-based cone-beam computed tomography (CBCT) has been widely used in C-arm imaging for spine surgery and interventional procedures. The system provides real-time fluoroscopy with high spatial resolution and three-dimensional (3D) visualization of anatomical structure without the need for patient transportation in interventional suite. In this work, a prototype CBCT imaging platform with continuous single rotation about the gantry was developed by using a large-area flat-panel detector with amorphous Si-based thin film transistor matrix. The different 2D projection images were acquired during constant gantry velocity for reconstructed images at a tube voltage of 80–120 kVp, and different current (10–50 mA) conditions. Various scan protocols were applied to a chest phantom human by changing the number of projection images and scanning angles. The projections were then reconstructed into a volumetric data of sections by using a 3D reconstruction algorithm (e.g., filtered back projection). The preliminary quantitative X-ray performance of our CBCT system was investigated by using the American Association of Physicists in Medicine CT phantom in terms of spatial resolution, contrast resolution, and CT number linearity for mobile or fixed C-arm based CBCT application with limited rotational geometry. The novel results of the projection data with different scanning angles and angular increments in the orbital gantry platform were acquired and evaluated experimentally

  11. High-quality 3D correction of ring and radiant artifacts in flat panel detector-based cone beam volume CT imaging

    International Nuclear Information System (INIS)

    Anas, Emran Mohammad Abu; Hasan, Md Kamrul; Kim, Jae Gon; Lee, Soo Yeol

    2011-01-01

    The use of an x-ray flat panel detector is increasingly becoming popular in 3D cone beam volume CT machines. Due to the deficient semiconductor array manufacturing process, the cone beam projection data are often corrupted by different types of abnormalities, which cause severe ring and radiant artifacts in a cone beam reconstruction image, and as a result, the diagnostic image quality is degraded. In this paper, a novel technique is presented for the correction of error in the 2D cone beam projections due to abnormalities often observed in 2D x-ray flat panel detectors. Template images are derived from the responses of the detector pixels using their statistical properties and then an effective non-causal derivative-based detection algorithm in 2D space is presented for the detection of defective and mis-calibrated detector elements separately. An image inpainting-based 3D correction scheme is proposed for the estimation of responses of defective detector elements, and the responses of the mis-calibrated detector elements are corrected using the normalization technique. For real-time implementation, a simplification of the proposed off-line method is also suggested. Finally, the proposed algorithms are tested using different real cone beam volume CT images and the experimental results demonstrate that the proposed methods can effectively remove ring and radiant artifacts from cone beam volume CT images compared to other reported techniques in the literature.

  12. The Usefulness of Three-Dimensional Angiography with a Flat Panel Detector of Direct Conversion Type in a Transcatheter Arterial Chemoembolization Procedure for Hepatocellular Carcinoma: Initial Experience

    International Nuclear Information System (INIS)

    Kakeda, Shingo; Korogi, Yukunori; Hatakeyama, Yoshihisa; Ohnari, Norihiro; Oda, Nobuhiro; Nishino, Kazuyoshi; Miyamoto, Wataru

    2008-01-01

    The purpose of this study was to assess the usefulness of a three-dimensional (3D) angiography system using a flat panel detector of direct conversion type in treatments with subsegmental transcatheter arterial chemoembolization (TACE) for hepatocellular carcinomas (HCCs). Thirty-six consecutive patients who underwent hepatic angiography were prospectively examined. First, two radiologists evaluated the degree of visualization of the peripheral branches of the hepatic arteries on 3D digital subtraction angiography (DSA). Then the radiologists evaluated the visualization of tumor staining and feeding arteries in 25 patients (30 HCCs) who underwent subsegmental TACE. The two radiologists who performed the TACE assessed whether the additional information provided by 3D DSA was useful for treatments. In 34 (94.4%) of 36 patients, the subsegmental branches of the hepatic arteries were sufficiently visualized. The feeding arteries of HCCs were sufficiently visualized in 28 (93%) of 30 HCCs, whereas tumor stains were sufficiently visualized in 18 (60%). Maximum intensity projection images were significantly superior to volume recording images for visualization of the tumor staining and feeding arteries of HCCs. In 27 (90%) of 30 HCCs, 3D DSA provided additional useful information for subsegmental TACE. The high-quality 3D DSA with flat panel detector angiography system provided a precise vascular road map, which was useful for performing subsegmental TACE .of HCCs

  13. TU-E-217BCD-06: Cone Beam Breast CT with a High Resolution Flat Panel Detector-Improvement of Calcification Visibility.

    Science.gov (United States)

    Shen, Y; Zhong, Y; Lai, C; Wang, T; Shaw, C

    2012-06-01

    To investigate the advantage of a high resolution flat panel detector for improving the visibility of microcalcifications (MCs) in cone beam breast CT Methods: A paraffin cylinder was used to simulate a 100% adipose breast. Calcium carbonate grains, ranging from 125-140 μm to 224 - 250 μm in size, were used to simulate the MCs. Groups of 25 same size MCs were embedded at the phantom center. The phantom was scanned with a bench-top CBCT system at various exposure levels. A 75μm pitch flat panel detector (Dexela 2923, Perkin Elmer) with 500μm thick CsI scintillator plate was used as the high resolution detector. A 194 μm pitch detector (Paxscan 4030CB, Varian Medical Systems) was used for reference. 300 projection images were acquired over 360° and reconstructed. The images were reviewed by 6 readers. The MC visibility was quantified as the fraction of visible MCs and averaged for comparison. The visibility was plotted as a function of the estimated dose level for various MC sizes and detectors. The MTFs and DQEs were measured and compared. For imaging small (200 μm and smaller) MCs, the visibility achieved with the 75μm pitch detector was found to be significantly higher than those achieved with the 194μm pitch detector. For imaging larger MCs, there was little advantage in using the 75μm pitch detector. Using the 75μm pitch detector, MCs as small as 180 μm could be imaged to achieve a visibility of 78% with an isocenter tissue dose of ∼20 mGys versus 62% achieved with the 194 μm pitch detector at the same dose level. It was found that a high pitch flat panel detector had the advantages of extending its imaging capability to higher frequencies thus helping improve the visibility when used to image small MCs. This work was supported in part by grants CA104759, CA13852 and CA124585 from NIH-NCI, a grant EB00117 from NIH-NIBIB, and a subcontract from NIST-ATP. © 2012 American Association of Physicists in Medicine.

  14. Cone beam breast CT with a high pitch (75 μm), thick (500 μm) scintillator CMOS flat panel detector: visibility of simulated microcalcifications.

    Science.gov (United States)

    Shen, Youtao; Zhong, Yuncheng; Lai, Chao-Jen; Wang, Tianpeng; Shaw, Chris C

    2013-10-01

    To measure and investigate the improvement of microcalcification (MC) visibility in cone beam breast CT with a high pitch (75 μm), thick (500 μm) scintillator CMOS/CsI flat panel detector (Dexela 2923, Perkin Elmer). Aluminum wires and calcium carbonate grains of various sizes were embedded in a paraffin cylinder to simulate imaging of calcifications in a breast. Phantoms were imaged with a benchtop experimental cone beam CT system at various exposure levels. In addition to the Dexela detector, a high pitch (50 μm), thin (150 μm) scintillator CMOS/CsI flat panel detector (C7921CA-09, Hamamatsu Corporation, Hamamatsu City, Japan) and a widely used low pitch (194 μm), thick (600 μm) scintillator aSi/CsI flat panel detector (PaxScan 4030CB, Varian Medical Systems) were also used in scanning for comparison. The images were independently reviewed by six readers (imaging physicists). The MC visibility was quantified as the fraction of visible MCs and measured as a function of the estimated mean glandular dose (MGD) level for various MC sizes and detectors. The modulation transfer functions (MTFs) and detective quantum efficiencies (DQEs) were also measured and compared for the three detectors used. The authors have demonstrated that the use of a high pitch (75 μm) CMOS detector coupled with a thick (500 μm) CsI scintillator helped make the smaller 150-160, 160-180, and 180-200 μm MC groups more visible at MGDs up to 10.8, 9, and 10.8 mGy, respectively. It also made the larger 200-212 and 212-224 μm MC groups more visible at MGDs up to 7.2 mGy. No performance improvement was observed for 224-250 μm or larger size groups. With the higher spatial resolution of the Dexela detector based system, the apparent dimensions and shapes of MCs were more accurately rendered. The results show that with the aforementioned detector, a 73% visibility could be achieved in imaging 160-180 μm MCs as compared to 28% visibility achieved by the low pitch (194 μm) aSi/CsI flat

  15. Development of high quantum efficiency, flat panel, thick detectors for megavoltage x-ray imaging: An experimental study of a single-pixel prototype

    International Nuclear Information System (INIS)

    Mei, X.; Pang, G.

    2005-01-01

    Our overall goal is to develop a new generation of electronic portal imaging devices (EPIDs) with a quantum efficiency (QE) more than an order of magnitude higher and a spatial resolution equivalent to that of EPIDs currently used for portal imaging. A novel design of such a high QE flat-panel based EPID was introduced recently and its feasibility was investigated theoretically [see Pang and Rowlands, Med. Phys. 31, 3004 (2004)]. In this work, we constructed a prototype single-pixel detector based on the novel design. Some fundamental imaging properties including the QE, spatial resolution, and sensitivity of the prototype detector were measured with a 6 MV beam. It has been shown that the experimental results agree well with theoretical predictions and further development based on the novel design including the construction of a prototype area detector is warranted

  16. High-EPA Biomass from Nannochloropsis salina Cultivated in a Flat-Panel Photo-Bioreactor on a Process Water-Enriched Growth Medium

    DEFF Research Database (Denmark)

    Safafar, Hamed; Hass, Michael Z.; Møller, Per

    2016-01-01

    salina biomass, with a focus on eicosapentaenoic acid (EPA). Variations in fatty acid composition, lipids, protein, amino acids, tocopherols and pigments were studied and results compared to algae cultivated on F/2 media as reference. Mixed growth media and process water enhanced the nutritional quality...... of Nannochloropsis salina in laboratory scale when compared to algae cultivated in standard F/2 medium. Data from laboratory scale translated to the large scaleusing a 4000 L flat panel photo-bioreactor system. The algae growth rate in winter conditions in Denmark was slow, but results revealed that large...... after 21 days of cultivation. Variations in chemical compositions of Nannochloropsis salina were studied during the course of cultivation. Nannochloropsis salina can be presented as a good candidate for winter time cultivation in Denmark.The resulting biomass is a rich source of EPA and also a good...

  17. Studies of the performance of different front-end systems for flat-panel multi-anode PMTs with CsI(Tl) scintillator arrays

    International Nuclear Information System (INIS)

    Sekiya, H.; Hattori, K.; Kubo, H.; Miuchi, K.; Nagayoshi, T.; Nishimura, H.; Okada, Y.; Orito, R.; Takada, A.; Takeda, A.; Tanimori, T.; Ueno, K.

    2006-01-01

    We have studied the performance of two different types of front-end systems for our gamma camera based on Hamamatsu H8500 (flat-panel 64 channels multi-anode PSPMT) with a CsI(Tl) scintillator array. The array consists of 64 pixels of 6x6x20mm 3 which corresponds to the anode pixels of H8500. One of the system is based on commercial ASIC chips in order to read out every anode. The others are based on resistive charge divider network between anodes to reduce readout channels. In both systems, each pixel (6mm) was clearly resolved by flood field irradiation of 137 Cs. We also investigated the energy resolution of these systems and showed the performance of the cascade connection of resistive network between some PMTs for large area detectors

  18. Radiation exposure to operating staff during rotational flat-panel angiography and C-arm cone beam computed tomography (CT) applications

    Energy Technology Data Exchange (ETDEWEB)

    Schulz, Boris, E-mail: boris.schell@googlemail.com [Goethe University Hospital, Department of Diagnostic and Interventional Radiology, Theodor-Stern-Kai 7, 60590 Frankfurt (Germany); Heidenreich, Ralf, E-mail: ralf.heidenreich@roentgen-consult.de [Röntgen-Consult Company, Schulhausstrasse 37, 79199 Kirchzarten (Germany); Heidenreich, Monika, E-mail: info@roentgen-consult.de [Röntgen-Consult Company, Schulhausstrasse 37, 79199 Kirchzarten (Germany); Eichler, Katrin, E-mail: k.eichler@em.uni-frankfurt.de [Goethe University Hospital, Department of Diagnostic and Interventional Radiology, Theodor-Stern-Kai 7, 60590 Frankfurt (Germany); Thalhammer, Axel, E-mail: axel.thalhammer@kgu.de [Goethe University Hospital, Department of Diagnostic and Interventional Radiology, Theodor-Stern-Kai 7, 60590 Frankfurt (Germany); Naeem, Naguib Nagy Naguib, E-mail: nagynnn@yahoo.com [Goethe University Hospital, Department of Diagnostic and Interventional Radiology, Theodor-Stern-Kai 7, 60590 Frankfurt (Germany); Vogl, Thomas Josef, E-mail: T.Vogl@em.uni-frankfurt.de [Goethe University Hospital, Department of Diagnostic and Interventional Radiology, Theodor-Stern-Kai 7, 60590 Frankfurt (Germany); Zangos, Stefan, E-mail: Zangos@em.uni-frankfurt.de [Goethe University Hospital, Department of Diagnostic and Interventional Radiology, Theodor-Stern-Kai 7, 60590 Frankfurt (Germany)

    2012-12-15

    Purpose: To evaluate the radiation exposure for operating personel associated with rotational flat-panel angiography and C-arm cone beam CT. Materials and methods: Using a dedicated angiography-suite, 2D and 3D examinations of the liver were performed on a phantom to generate scattered radiation. Exposure was measured with a dosimeter at predefined heights (eye, thyroid, breast, gonads and knee) at the physician's location. Analysis included 3D procedures with a field of view (FOV) of 24 cm × 18 cm (8 s/rotation, 20 s/rotation and 5 s/2 rotations), and 47 cm × 18 cm (16 s/2 rotations) and standard 2D angiography (10 s, FOV 24 cm × 18 cm). Results: Measurements showed the highest radiation dose at the eye and thyroid level. In comparison to 2D-DSA (3.9 μSv eye-exposure), the 3D procedures caused an increased radiation exposure both in standard FOV (8 s/rotation: 28.0 μSv, 20 s/rotation: 79.3 μSv, 5 s/2 rotations: 32.5 μSv) and large FOV (37.6 μSv). Proportional distributions were measured for the residual heights. With the use of lead glass, irradiation of the eye lens was reduced to 0.2 μSv (2D DSA) and 10.6 μSv (3D technique with 20 s/rotation). Conclusion: Rotational flat-panel angiography and C-arm cone beam applications significantly increase radiation exposure to the attending operator in comparison to 2D angiography. Our study indicates that the physician should wear protective devices and leave the examination room when performing 3D examinations.

  19. Radiation exposure to operating staff during rotational flat-panel angiography and C-arm cone beam computed tomography (CT) applications.

    Science.gov (United States)

    Schulz, Boris; Heidenreich, Ralf; Heidenreich, Monika; Eichler, Katrin; Thalhammer, Axel; Naeem, Naguib Nagy Naguib; Vogl, Thomas Josef; Zangos, Stefan

    2012-12-01

    To evaluate the radiation exposure for operating personnel associated with rotational flat-panel angiography and C-arm cone beam CT. Using a dedicated angiography-suite, 2D and 3D examinations of the liver were performed on a phantom to generate scattered radiation. Exposure was measured with a dosimeter at predefined heights (eye, thyroid, breast, gonads and knee) at the physician's location. Analysis included 3D procedures with a field of view (FOV) of 24 cm × 18 cm (8s/rotation, 20s/rotation and 5s/2 rotations), and 47 cm×18 cm (16s/2 rotations) and standard 2D angiography (10s, FOV 24 cm×18 cm). Measurements showed the highest radiation dose at the eye and thyroid level. In comparison to 2D-DSA (3.9 μSv eye-exposure), the 3D procedures caused an increased radiation exposure both in standard FOV (8s/rotation: 28.0 μSv, 20s/rotation: 79.3 μSv, 5s/2 rotations: 32.5 μSv) and large FOV (37.6 μSv). Proportional distributions were measured for the residual heights. With the use of lead glass, irradiation of the eye lens was reduced to 0.2 μSv (2D DSA) and 10.6 μSv (3D technique with 20s/rotation). Rotational flat-panel angiography and C-arm cone beam applications significantly increase radiation exposure to the attending operator in comparison to 2D angiography. Our study indicates that the physician should wear protective devices and leave the examination room when performing 3D examinations. Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.

  20. Radiation exposure to operating staff during rotational flat-panel angiography and C-arm cone beam computed tomography (CT) applications

    International Nuclear Information System (INIS)

    Schulz, Boris; Heidenreich, Ralf; Heidenreich, Monika; Eichler, Katrin; Thalhammer, Axel; Naeem, Naguib Nagy Naguib; Vogl, Thomas Josef; Zangos, Stefan

    2012-01-01

    Purpose: To evaluate the radiation exposure for operating personel associated with rotational flat-panel angiography and C-arm cone beam CT. Materials and methods: Using a dedicated angiography-suite, 2D and 3D examinations of the liver were performed on a phantom to generate scattered radiation. Exposure was measured with a dosimeter at predefined heights (eye, thyroid, breast, gonads and knee) at the physician's location. Analysis included 3D procedures with a field of view (FOV) of 24 cm × 18 cm (8 s/rotation, 20 s/rotation and 5 s/2 rotations), and 47 cm × 18 cm (16 s/2 rotations) and standard 2D angiography (10 s, FOV 24 cm × 18 cm). Results: Measurements showed the highest radiation dose at the eye and thyroid level. In comparison to 2D-DSA (3.9 μSv eye-exposure), the 3D procedures caused an increased radiation exposure both in standard FOV (8 s/rotation: 28.0 μSv, 20 s/rotation: 79.3 μSv, 5 s/2 rotations: 32.5 μSv) and large FOV (37.6 μSv). Proportional distributions were measured for the residual heights. With the use of lead glass, irradiation of the eye lens was reduced to 0.2 μSv (2D DSA) and 10.6 μSv (3D technique with 20 s/rotation). Conclusion: Rotational flat-panel angiography and C-arm cone beam applications significantly increase radiation exposure to the attending operator in comparison to 2D angiography. Our study indicates that the physician should wear protective devices and leave the examination room when performing 3D examinations.

  1. Thermo-enhanced field emission from ZnO nanowires: Role of defects and application in a diode flat panel X-ray source

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, Zhipeng; Chen, Daokun; Chen, Wenqing; Chen, Yicong; Song, Xiaomeng; Zhan, Runze; Deng, Shaozhi; Xu, Ningsheng; Chen, Jun, E-mail: stscjun@mail.sysu.edu.cn

    2017-03-31

    Highlights: • A thermo-enhanced field emission phenomenon was observed from dendritic ZnO nanowires under the temperature of 323–723 K. • Defect-assisted field emission mechanism was proposed and quantitative calculation fits well with the experiment results. • The mechanism was verified by the field emission from ZnO nanowires with different defect concentrations. • A diode X-ray source making use of thermo-enhanced field emission phenomenon was proposed for separate tuning of dose and energy. - Abstract: A thermo-enhanced field emission phenomenon was observed from ZnO nanowires. The field emission current increased by almost two orders of magnitude under a constant applied electric field, and the turn-on field decreased from 6.04 MV/m to 5.0 MV/m when the temperature increased from 323 to 723 K. The Poole–Frenkel electron excitation from the defect-induced trapping centers to the conduction band under high electric fields is believed to be the primary cause of the observed phenomenon. The experimental results fit well with the proposed physical model. The field emission from ZnO nanowires with different defect concentrations further confirmed the role of defects. Using the thermo-enhanced field emission phenomenon, a diode flat panel X-ray source was demonstrated, for which the energy and dose can be separately tuned. The thermo-enhanced field emission phenomenon observed from ZnO nanowires could be an effective way to realize a large area flat panel multi-energy X-ray source.

  2. The impact of round window vs cochleostomy surgical approaches on interscalar excursions in the cochlea: Preliminary results from a flat-panel computed tomography study

    Directory of Open Access Journals (Sweden)

    Nicole T. Jiam

    2016-09-01

    Full Text Available Objective: To evaluate incidence of interscalar excursions between round window (RW and cochleostomy approaches for cochlear implant (CI insertion. Methods: This was a retrospective case-comparison. Flat-panel CT (FPCT scans for 8 CI users with Med-El standard length electrode arrays were collected. Surgical technique was identified by a combination of operative notes and FPCT imaging. Four cochleae underwent round window insertion and 4 cochleae underwent cochleostomy approaches anterior and inferior to the round window. Results: In our pilot study, cochleostomy approaches were associated with a higher likelihood of interscalar excursion. Within the cochleostomy group, we found 29% of electrode contacts (14 of 48 electrodes to be outside the scala tympani. On the other hand, 8.5% of the electrode contacts (4 of 47 electrodes in the round window insertion group were extra-scalar to the scala tympani. These displacements occurred at a mean angle of occurrence of 364° ± 133°, near the apex of the cochlea. Round window electrode displacements tend to localize at angle of occurrences of 400° or greater. Cochleostomy electrodes occurred at an angle of occurrence of 19°–490°. Conclusions: Currently, the optimal surgical approach for standard CI electrode insertion is highly debated, to a certain extent due to a lack of post-operative assessment of intracochlear electrode contact. Based on our preliminary findings, cochleostomy approach is associated with an increased likelihood of interscalar excursions, and these findings should be further evaluated with future prospective studies. Keywords: Cochlear implantation, Round window insertion, Cochleostomy, Interscalar excursion, Electrode position, Flat-panel computed tomography, Surgical approach

  3. Detection of Cement Leakage After Vertebroplasty with a Non-Flat-Panel Angio Unit Compared to Multidetector Computed Tomography - An Ex Vivo Study

    International Nuclear Information System (INIS)

    Baumann, Clemens; Fuchs, Heiko; Westphalen, Kerstin; Hierholzer, Johannes

    2008-01-01

    The purpose of this study was to investigate the detection of cement leakages after vertebroplasty using angiographic computed tomography (ACT) in a non-flat-panel angio unit compared to multidetector computed tomography (MDCT). Vertebroplasty was performed in 19 of 33 cadaver vertebrae (23 thoracic and 10 lumbar segments). In the angio suite, ACT (190 o ; 1.5 o per image) was performed to obtain volumetric data. Another volumetric data set of the specimen was obtained by MDCT using a standard algorithm. Nine multiplanar reconstructions in standardized axial, coronal, and sagittal planes of every vertebra were generated from both data sets. Images were evaluated on the basis of a nominal scale with 18 criteria, comprising osseous properties (e.g., integrity of the end plate) and cement distribution (e.g., presence of intraspinal cement). MDCT images were regarded as gold standard and analyzed by two readers in a consensus mode. Rotational acquisitions were analyzed by six blinded readers. Results were correlated with the gold standard using Cohen's κ-coefficient analysis. Furthermore, interobserver variability was calculated. Correlation with the gold standard ranged from no correlation (osseous margins of the neuroforamen, κ = 0.008) to intermediate (trace of vertebroplasty canula; κ = 0.615) for criteria referring to osseous morphology. However, there was an excellent correlation for those criteria referring to cement distribution, with κ values ranging from 0.948 (paravertebral cement distribution) to 0.972 (intraspinal cement distribution). With a minimum of κ = 0.768 ('good correlation') and a maximum of κ = 0.91 ('excellent'), interobserver variability was low. In conclusion, ACT in an angio suite without a flat-panel detector depicts a cement leakage after vertebroplasty as well as MDCT. However, the method does not provide sufficient depiction of osseous morphology.

  4. Standard practice for acoustic emission examination of plate-like and flat panel composite structures used in aerospace applications

    CERN Document Server

    American Society for Testing and Materials. Philadelphia

    2010-01-01

    1.1 This practice covers acoustic emission (AE) examination or monitoring of panel and plate-like composite structures made entirely of fiber/polymer composites. 1.2 The AE examination detects emission sources and locates the region(s) within the composite structure where the emission originated. When properly developed AE-based criteria for the composite item are in place, the AE data can be used for nondestructive examination (NDE), characterization of proof testing, documentation of quality control or for decisions relative to structural-test termination prior to completion of a planned test. Other NDE methods may be used to provide additional information about located damage regions. For additional information see Appendix X1. 1.3 This practice can be applied to aerospace composite panels and plate-like elements as a part of incoming inspection, during manufacturing, after assembly, continuously (during structural health monitoring) and at periodic intervals during the life of a structure. 1.4 This pra...

  5. Volumetric breast density estimation from full-field digital mammograms.

    NARCIS (Netherlands)

    Engeland, S. van; Snoeren, P.R.; Huisman, H.J.; Boetes, C.; Karssemeijer, N.

    2006-01-01

    A method is presented for estimation of dense breast tissue volume from mammograms obtained with full-field digital mammography (FFDM). The thickness of dense tissue mapping to a pixel is determined by using a physical model of image acquisition. This model is based on the assumption that the breast

  6. Calibration and validation of full-field techniques

    Directory of Open Access Journals (Sweden)

    Thalmann R.

    2010-06-01

    Full Text Available We review basic metrological terms related to the use of measurement equipment for verification of numerical model calculations. We address three challenges that are faced when performing measurements in experimental mechanics with optical techniques: the calibration of a measuring instrument that (i measures strain values, (ii provides full-field data, and (iii is dynamic.

  7. No-contact method of determining average working-surface temperature of plate-type radiation-absorbing thermal exchange panels of flat solar collectors for heating heat-transfer fluid

    International Nuclear Information System (INIS)

    Avezova, N.R.; Avezov, R.R.

    2015-01-01

    A brand new no-contact method of determining the average working-surface temperature of plate-type radiation-absorbing thermal exchange panels (RATEPs) of flat solar collectors (FSCs) for heating a heat-transfer fluid (HTF) is suggested on the basis of the results of thermal tests in full-scale quasistationary conditions. (authors)

  8. Report of the results of the fiscal 1997 regional consortium R and D project. Regional consortium energy field/R and D high performance flat panel display technology (first fiscal year); 1997 nendo chiiki consortium kenkyu kaihatsu jigyo. Chiiki consortium energy bun`ya / koseino flat panel display gijutsu no sogo kaihatsu kenkyu (daiichi nendo ) seika hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-03-01

    One of the subjects in technology supporting the highly information-oriented society which will develop and diversify toward the 21st century is the construction of high grade man/machine interface. For it, high precision/high luminance/energy saving/thin plane displays are strongly requested. This R and D is to indicate models of systematical development in the region of element technology individually existing in the Shikoku area by forming a regional consortium in the industry/universities/government. Creation of new industries by gathering display related enterprises is a first step in a plan to realize `Display Island Shikoku.` As a concrete target, with the use of high-tech diamond semiconducting technology, a development is conducted of the high performance flat panel display using the negative electron affinity (NEA) electron emitter which drastically solves the problems such as luminance, visibility angle and response speed, the subjects on the commercialized liquid crystal flat panel display. 16 refs., 45 figs., 8 tabs.

  9. Flat panel detector-based cone beam computed tomography with a circle-plus-two-arcs data acquisition orbit: Preliminary phantom study

    International Nuclear Information System (INIS)

    Ning Ruola; Tang Xiangyang; Conover, David; Yu Rongfeng

    2003-01-01

    Cone beam computed tomography (CBCT) has been investigated in the past two decades due to its potential advantages over a fan beam CT. These advantages include (a) great improvement in data acquisition efficiency, spatial resolution, and spatial resolution uniformity, (b) substantially better utilization of x-ray photons generated by the x-ray tube compared to a fan beam CT, and (c) significant advancement in clinical three-dimensional (3D) CT applications. However, most studies of CBCT in the past are focused on cone beam data acquisition theories and reconstruction algorithms. The recent development of x-ray flat panel detectors (FPD) has made CBCT imaging feasible and practical. This paper reports a newly built flat panel detector-based CBCT prototype scanner and presents the results of the preliminary evaluation of the prototype through a phantom study. The prototype consisted of an x-ray tube, a flat panel detector, a GE 8800 CT gantry, a patient table and a computer system. The prototype was constructed by modifying a GE 8800 CT gantry such that both a single-circle cone beam acquisition orbit and a circle-plus-two-arcs orbit can be achieved. With a circle-plus-two-arcs orbit, a complete set of cone beam projection data can be obtained, consisting of a set of circle projections and a set of arc projections. Using the prototype scanner, the set of circle projections were acquired by rotating the x-ray tube and the FPD together on the gantry, and the set of arc projections were obtained by tilting the gantry while the x-ray tube and detector were at the 12 and 6 o'clock positions, respectively. A filtered backprojection exact cone beam reconstruction algorithm based on a circle-plus-two-arcs orbit was used for cone beam reconstruction from both the circle and arc projections. The system was first characterized in terms of the linearity and dynamic range of the detector. Then the uniformity, spatial resolution and low contrast resolution were assessed using

  10. A novel full-field experimental method to measure the local compressibility of gas diffusion media

    Energy Technology Data Exchange (ETDEWEB)

    Lai, Yeh-Hung; Li, Yongqiang [Electrochemical Energy Research Lab, GM R and D, Honeoye Falls, NY 14472 (United States); Rock, Jeffrey A. [GM Powertrain, Honeoye Falls, NY 14472 (United States)

    2010-05-15

    The gas diffusion medium (GDM) in a proton exchange membrane (PEM) fuel cell needs to simultaneously satisfy the requirements of transporting reactant gases, removing product water, conducting electrons and heat, and providing mechanical support to the membrane electrode assembly (MEA). Concerning the localized over-compression which may force carbon fibers and other conductive debris into the membrane to cause fuel cell failure by electronically shorting through the membrane, we have developed a novel full-field experimental method to measure the local thickness and compressibility of GDM. Applying a uniform air pressure upon a thin polyimide film bonded on the top surface of the GDM with support from the bottom by a flat metal substrate and measuring the thickness change using the 3-D digital image correlation technique with an out-of-plane displacement resolution less than 0.5 {mu}m, we have determined the local thickness and compressive stress/strain behavior in the GDM. Using the local thickness and compressibility data over an area of 11.2 mm x 11.2 mm, we numerically construct the nominal compressive response of a commercial Toray trademark TGP-H-060 based GDM subjected to compression by flat platens. Good agreement in the nominal stress/strain curves from the numerical construction and direct experimental flat-platen measurement confirms the validity of the methodology proposed in this article. The result shows that a nominal pressure of 1.4 MPa compressed between two flat platens can introduce localized compressive stress concentration of more than 3 MPa in up to 1% of the total area at various locations from several hundred micrometers to 1 mm in diameter. We believe that this full-field experimental method can be useful in GDM material and process development to reduce the local hard spots and help to mitigate the membrane shorting failure in PEM fuel cells. (author)

  11. A novel full-field experimental method to measure the local compressibility of gas diffusion media

    Science.gov (United States)

    Lai, Yeh-Hung; Li, Yongqiang; Rock, Jeffrey A.

    The gas diffusion medium (GDM) in a proton exchange membrane (PEM) fuel cell needs to simultaneously satisfy the requirements of transporting reactant gases, removing product water, conducting electrons and heat, and providing mechanical support to the membrane electrode assembly (MEA). Concerning the localized over-compression which may force carbon fibers and other conductive debris into the membrane to cause fuel cell failure by electronically shorting through the membrane, we have developed a novel full-field experimental method to measure the local thickness and compressibility of GDM. Applying a uniform air pressure upon a thin polyimide film bonded on the top surface of the GDM with support from the bottom by a flat metal substrate and measuring the thickness change using the 3-D digital image correlation technique with an out-of-plane displacement resolution less than 0.5 μm, we have determined the local thickness and compressive stress/strain behavior in the GDM. Using the local thickness and compressibility data over an area of 11.2 mm × 11.2 mm, we numerically construct the nominal compressive response of a commercial Toray™ TGP-H-060 based GDM subjected to compression by flat platens. Good agreement in the nominal stress/strain curves from the numerical construction and direct experimental flat-platen measurement confirms the validity of the methodology proposed in this article. The result shows that a nominal pressure of 1.4 MPa compressed between two flat platens can introduce localized compressive stress concentration of more than 3 MPa in up to 1% of the total area at various locations from several hundred micrometers to 1 mm in diameter. We believe that this full-field experimental method can be useful in GDM material and process development to reduce the local hard spots and help to mitigate the membrane shorting failure in PEM fuel cells.

  12. Hydrogen production by the engineered cyanobacterial strain Nostoc PCC 7120 ΔhupW examined in a flat panel photobioreactor system.

    Science.gov (United States)

    Nyberg, Marcus; Heidorn, Thorsten; Lindblad, Peter

    2015-12-10

    Nitrogenase based hydrogen production was examined in a ΔhupW strain of the filamentous heterocystous cyanobacterium Nostoc PCC 7120, i.e., cells lacking the last step in the maturation system of the large subunit of the uptake hydrogenase and as a consequence with a non-functional uptake hydrogenase. The cells were grown in a developed flat panel photobioreactor system with 3.0L culture volume either aerobically (air) or anaerobically (Ar or 80% N2/20% Ar) and illuminated with a mixture of red and white LED. Aerobic growth of the ΔhupW strain of Nostoc PCC 7120 at 44μmolar photons m(-2)s(-1) PAR gave the highest hydrogen production of 0.7mL H2 L(-1)h(-1), 0.53mmol H2 mg chlorophyll a(-1)h(-1), and a light energy conversion efficiency of 1.2%. Anaerobic growth using 100% argon showed a maximal hydrogen production of 1.7mLL(-1)h(-1), 0.85mmol per mg chlorophyll a(-1) h(-1), and a light energy conversion efficiency of 2.7%. Altering between argon/N2 (20/80) and 100% argon phases resulted in a maximal hydrogen production at hour 128 (100% argon phase) with 6.2mL H2L(-1)h(-1), 0.71mL H2 mg chlorophyll a(-1)h(-1), and a light energy efficiency conversion of 4.0%. The highest buildup of hydrogen gas observed was 6.89% H2 (100% argon phase) of the total photobioreactor system with a maximal production of 4.85mL H2 L(-1)h(-1). The present study clearly demonstrates the potential to use purpose design cyanobacteria in developed flat panel photobioreactor systems for the direct production of the solar fuel hydrogen. Further improvements in the strain used, environmental conditions employed, and growth, production and collection systems used, are needed before a sustainable and economical cyanobacterial based hydrogen production can be realized. Copyright © 2015 Elsevier B.V. All rights reserved.

  13. The Effect of Round Window vs Cochleostomy Surgical Approaches on Cochlear Implant Electrode Position: A Flat-Panel Computed Tomography Study.

    Science.gov (United States)

    Jiam, Nicole T; Jiradejvong, Patpong; Pearl, Monica S; Limb, Charles J

    2016-09-01

    The round window insertion (RWI) and cochleostomy approaches are the 2 most common surgical techniques used in cochlear implantation (CI). However, there is no consensus on which approach is ideal for electrode array insertion, in part because visualization of intracochlear electrode position is challenging, so postoperative assessment of intracochlear electrode contact is lacking. To measure and compare electrode array position between RWI and cochleostomy approaches for CI insertion. Retrospective case-comparison study of 17 CI users with Med-El standard-length electrode arrays who underwent flat-panel computed tomography scans after CI surgery at a tertiary referral center. The data was analyzed in October 2015. Flat-panel computed tomography scans were collected between January 1 and August 31, 2013, for 22 electrode arrays. The surgical technique was identified by a combination of operative notes and imaging. Eight cochleae underwent RWI and 14 cochleae underwent cochleostomy approaches anterior and inferior to the round window. Interscalar electrode position and electrode centroid distance to the osseous spiral lamina, lateral bony wall, and central axis of the modiolus. Nine participants were men, and 8, women; the mean age was 54.4 (range, 21-64) years. Electrode position was significantly closer to cochlear neural elements with RWI than cochleostomy approaches. Between the 2 surgical approaches, the RWI technique produced shorter distances between the electrode and the modiolus (mean difference, -0.33 [95% CI, -0.29 to -0.39] mm in the apical electrode; -1.42 [95% CI, -1.24 to -1.57] mm in the basal electrode). This difference, which was most prominent in the first third and latter third of the basal turn, decreased after the basal turn. The RWI approach was associated with an increased likelihood of perimodiolar placement. Opting to use RWI over cochleostomy approaches in CI candidates may position electrodes closer to cochlear neural substrates and

  14. Full-Field Indentation Damage Measurement Using Digital Image Correlation

    Directory of Open Access Journals (Sweden)

    Elías López-Alba

    2017-07-01

    Full Text Available A novel approach based on full-field indentation measurements to characterize and quantify the effect of contact in thin plates is presented. The proposed method has been employed to evaluate the indentation damage generated in the presence of bending deformation, resulting from the contact between a thin plate and a rigid sphere. For this purpose, the 3D Digital Image Correlation (3D-DIC technique has been adopted to quantify the out of plane displacements at the back face of the plate. Tests were conducted using aluminum thin plates and a rigid bearing sphere to evaluate the influence of the thickness and the material behavior during contact. Information provided by the 3D-DIC technique has been employed to perform an indirect measurement of the contact area during the loading and unloading path of the test. A symmetrical distribution in the contact damage region due to the symmetry of the indenter was always observed. In the case of aluminum plates, the presence of a high level of plasticity caused shearing deformation as the load increased. Results show the full-field contact damage area for different plates’ thicknesses at different loads. The contact damage region was bigger when the thickness of the specimen increased, and therefore, bending deformation was reduced. With the proposed approach, the elastic recovery at the contact location was quantified during the unloading, as well as the remaining permanent indentation damage after releasing the load. Results show the information obtained by full-field measurements at the contact location during the test, which implies a substantial improvement compared with pointwise techniques.

  15. Non-destructive, preclinical evaluation of root canal anatomy of human teeth with flat-panel detector volume CT (FD-VCT)

    International Nuclear Information System (INIS)

    Heidrich, G.; Hassepass, F.; Dullin, C.; Grabbe, E.; Attin, T.; Hannig, C.

    2005-01-01

    Purpose: Successful endodontic diagnostics and therapy call for adequate depiction of the root canal anatomy with multimodal diagnostic imaging. The aim of the present study is to evaluate visualization of the endodont with flat-panel detector volume CT (FD-VCT). Materials and methods: 13 human teeth were examined with the prototype of a FD-VCT. After data acquisition and generation of volume data sets in volume rendering technology (VRT), the findings obtained were compared to conventional X-rays and cross-section preparations of the teeth. Results: The anatomical structures of the endodont such as root canals, side canals and communications between different root canals as well as dentricles could be detected precisely with FD-VCT. The length of curved root canals was also determined accurately. The spatial resolution of the system is around 140 μm. Only around 73% of the main root canals detected with FD-VCT and 87% of the roots could be visualized with conventional dental X-rays. None of the side canals, shown with FD-VCT, was detectable on conventional X-rays. In all cases the enamel and dentin of the teeth could be well delineated. No differences in image quality could be discerned between stored and freshly extracted teeth, or between primary and adult teeth. (orig.)

  16. Flat-Panel Detector—Based Volume Computed Tomography: A Novel 3D Imaging Technique to Monitor Osteolytic Bone Lesions in a Mouse Tumor Metastasis Model

    Directory of Open Access Journals (Sweden)

    Jeannine Missbach-Guentner

    2007-09-01

    Full Text Available Skeletal metastasis is an important cause of mortality in patients with breast cancer. Hence, animal models, in combination with various imaging techniques, are in high demand for preclinical assessment of novel therapies. We evaluated the applicability of flat-panel volume computed tomography (fpVCT to noninvasive detection of osteolytic bone metastases that develop in severe immunodeficient mice after intracardial injection of MDA-MB-231 breast cancer cells. A single fpVCT scan at 200-wm isotropic resolution was employed to detect osteolysis within the entire skeleton. Osteolytic lesions identified by fpVCT correlated with Faxitron X-ray analysis and were subsequently confirmed by histopathological examination. Isotropic three-dimensional image data sets obtained by fpVCT were the basis for the precise visualization of the extent of the lesion within the cortical bone and for the measurement of bone loss. Furthermore, fpVCT imaging allows continuous monitoring of growth kinetics for each metastatic site and visualization of lesions in more complex regions of the skeleton, such as the skull. Our findings suggest that fpVCT is a powerful tool that can be used to monitor the occurrence and progression of osteolytic lesions in vivo and can be further developed to monitor responses to antimetastatic therapies over the course of the disease.

  17. Concept of a selective tumour therapy and its evaluation by near-infrared fluorescence imaging and flat-panel volume computed tomography in mice.

    Science.gov (United States)

    Alves, Frauke; Dullin, Christian; Napp, Joanna; Missbach-Guentner, Jeannine; Jannasch, Katharina; Mathejczyk, Julia; Pardo, Luis A; Stühmer, Walter; Tietze, Lutz-F

    2009-05-01

    Conventional chemotherapy of cancer has its limitations, especially in advanced and disseminated disease and suffers from lack of specificity. This results in a poor therapeutic index and considerable toxicity to normal organs. Therefore, many efforts are made to develop novel therapeutic tools against cancer with the aim of selectively targeting the drug to the tumour site. Drug delivery strategies fundamentally rely on the identification of good-quality biomarkers, allowing unequivocal discrimination between cancer and healthy tissue. At present, antibodies or antibody fragments have clearly proven their value as carrier molecules specific for a tumour-associated molecular marker. This present review draws attention to the use of near-infrared fluorescence (NIRF) imaging to investigate binding specificity and kinetics of carrier molecules such as monoclonal antibodies. In addition, flat-panel volume computed tomography (fpVCT) will be presented to monitor anatomical structures in tumour mouse models over time in a non-invasive manner. Each imaging device sheds light on a different aspect; functional imaging is applied to optimise the dose schedule and the concept of selective tumour therapies, whereas anatomical imaging assesses preclinically the efficacy of novel tumour therapies. Both imaging techniques in combination allow the visualisation of functional information obtained by NIRF imaging within an adequate anatomic framework.

  18. Does Preinterventional Flat-Panel Computer Tomography Pooled Blood Volume Mapping Predict Final Infarct Volume After Mechanical Thrombectomy in Acute Cerebral Artery Occlusion?

    International Nuclear Information System (INIS)

    Wagner, Marlies; Kyriakou, Yiannis; Mesnil de Rochemont, Richard du; Singer, Oliver C.; Berkefeld, Joachim

    2013-01-01

    PurposeDecreased cerebral blood volume is known to be a predictor for final infarct volume in acute cerebral artery occlusion. To evaluate the predictability of final infarct volume in patients with acute occlusion of the middle cerebral artery (MCA) or the distal internal carotid artery (ICA) and successful endovascular recanalization, pooled blood volume (PBV) was measured using flat-panel detector computed tomography (FPD CT).Materials and MethodsTwenty patients with acute unilateral occlusion of the MCA or distal ACI without demarcated infarction, as proven by CT at admission, and successful Thrombolysis in cerebral infarction score (TICI 2b or 3) endovascular thrombectomy were included. Cerebral PBV maps were acquired from each patient immediately before endovascular thrombectomy. Twenty-four hours after recanalization, each patient underwent multislice CT to visualize final infarct volume. Extent of the areas of decreased PBV was compared with the final infarct volume proven by follow-up CT the next day.ResultsIn 15 of 20 patients, areas of distinct PBV decrease corresponded to final infarct volume. In 5 patients, areas of decreased PBV overestimated final extension of ischemia probably due to inappropriate timing of data acquisition and misery perfusion.ConclusionPBV mapping using FPD CT is a promising tool to predict areas of irrecoverable brain parenchyma in acute thromboembolic stroke. Further validation is necessary before routine use for decision making for interventional thrombectomy

  19. A high-resolution full-field range imaging system

    Science.gov (United States)

    Carnegie, D. A.; Cree, M. J.; Dorrington, A. A.

    2005-08-01

    There exist a number of applications where the range to all objects in a field of view needs to be obtained. Specific examples include obstacle avoidance for autonomous mobile robots, process automation in assembly factories, surface profiling for shape analysis, and surveying. Ranging systems can be typically characterized as being either laser scanning systems where a laser point is sequentially scanned over a scene or a full-field acquisition where the range to every point in the image is simultaneously obtained. The former offers advantages in terms of range resolution, while the latter tend to be faster and involve no moving parts. We present a system for determining the range to any object within a camera's field of view, at the speed of a full-field system and the range resolution of some point laser scans. Initial results obtained have a centimeter range resolution for a 10 second acquisition time. Modifications to the existing system are discussed that should provide faster results with submillimeter resolution.

  20. Full-field measurements and identification in solid mechanics

    CERN Document Server

    Grediac, Michel

    2008-01-01

    This timely book presents cutting-edge developments by experts in the field on the rapidly developing and scientifically challenging area of full-field measurement techniques used in solid mechanics - including photoelasticity, grid methods, deflectometry, holography, speckle interferometry and digital image correlation. The evaluation of strains and the use of the measurements in subsequent parameter identification techniques to determine material properties are also presented. Since parametric identification techniques require a close coupling of theoretical models and experimental measurements, the book focuses on specific modeling approaches that include finite element model updating, the equilibrium gap method, constitutive equation gap method, virtual field method and reciprocity gap method. In the latter part of the book, the authors discuss two particular applications of selected methods that are of special interest to many investigators: the analysis of localized phenomenon and connections between mi...

  1. Quantification of breast arterial calcification using full field digital mammography

    International Nuclear Information System (INIS)

    Molloi, Sabee; Xu Tong; Ducote, Justin; Iribarren, Carlos

    2008-01-01

    Breast arterial calcification is commonly detected on some mammograms. Previous studies indicate that breast arterial calcification is evidence of general atherosclerotic vascular disease and it may be a useful marker of coronary artery disease. It can potentially be a useful tool for assessment of coronary artery disease in women since mammography is widely used as a screening tool for early detection of breast cancer. However, there are currently no available techniques for quantification of calcium mass using mammography. The purpose of this study was to determine whether it is possible to quantify breast arterial calcium mass using standard digital mammography. An anthropomorphic breast phantom along with a vessel calcification phantom was imaged using a full field digital mammography system. Densitometry was used to quantify calcium mass. A calcium calibration measurement was performed at each phantom thickness and beam energy. The known (K) and measured (M) calcium mass on 5 and 9 cm thickness phantoms were related by M=0.964K-0.288 mg (r=0.997 and SEE=0.878 mg) and M=1.004K+0.324 mg (r=0.994 and SEE=1.32 mg), respectively. The results indicate that accurate calcium mass measurements can be made without correction for scatter glare as long as careful calcium calibration is made for each breast thickness. The results also indicate that composition variations and differences of approximately 1 cm between calibration phantom and breast thickness introduce only minimal error in calcium measurement. The uncertainty in magnification is expected to cause up to 5% and 15% error in calcium mass for 5 and 9 cm breast thicknesses, respectively. In conclusion, a densitometry technique for quantification of breast arterial calcium mass was validated using standard full field digital mammography. The results demonstrated the feasibility and potential utility of the densitometry technique for accurate quantification of breast arterial calcium mass using standard digital

  2. Dependence of the coefficient of environmental thermal losses of radiation-absorbing thermal exchange panels of flat solar collectors for heating heat-transfer fluid from their average operating and ambient temperatures

    International Nuclear Information System (INIS)

    Avezova, N.R.; Avezov, R.R.

    2015-01-01

    The approximation formula is derived for calculating the normalized coefficient of thermal losses of flat solar collectors (FSCs) for heating heat-transfer fluid (HTF). These are used in hot water supply systems in the warmer part of the year, depending on the average working surface temperature of their radiation-absorbing thermal exchange panels (RATEPs) (t"-_w_s_r) and the ambient temperature (t_a_m_b) in their realistic variation range. (author)

  3. Quantitative comparison using Generalized Relative Object Detectability (G-ROD) metrics of an amorphous selenium detector with high resolution Microangiographic Fluoroscopes (MAF) and standard flat panel detectors (FPD).

    Science.gov (United States)

    Russ, M; Shankar, A; Jain, A; Setlur Nagesh, S V; Ionita, C N; Scott, C; Karim, K S; Bednarek, D R; Rudin, S

    2016-02-27

    A novel amorphous selenium (a-Se) direct detector with CMOS readout has been designed, and relative detector performance investigated. The detector features include a 25 μ m pixel pitch, and 1000 μ m thick a-Se layer operating at 10V/ μ m bias field. A simulated detector DQE was determined, and used in comparative calculations of the Relative Object Detectability (ROD) family of prewhitening matched-filter (PWMF) observer and non-prewhitening matched filter (NPWMF) observer model metrics to gauge a-Se detector performance against existing high resolution micro-angiographic fluoroscopic (MAF) detectors and a standard flat panel detector (FPD). The PWMF-ROD or ROD metric compares two x-ray imaging detectors in their relative abilities in imaging a given object by taking the integral over spatial frequencies of the Fourier transform of the detector DQE weighted by an object function, divided by the comparable integral for a different detector. The generalized-ROD (G-ROD) metric incorporates clinically relevant parameters (focal-spot size, magnification, and scatter) to show the degradation in imaging performance for detectors that are part of an imaging chain. Preliminary ROD calculations using simulated spheres as the object predicted superior imaging performance by the a-Se detector as compared to existing detectors. New PWMF-G-ROD and NPWMF-G-ROD results still indicate better performance by the a-Se detector in an imaging chain over all sphere sizes for various focal spot sizes and magnifications, although a-Se performance advantages were degraded by focal spot blurring. Nevertheless, the a-Se technology has great potential to provide breakthrough abilities such as visualization of fine details including of neuro-vascular perforator vessels and of small vascular devices.

  4. Imaging responses of on-site CsI and Gd2O2S flat-panel detectors: Dependence on the tube voltage

    Science.gov (United States)

    Jeon, Hosang; Chung, Myung Jin; Youn, Seungman; Nam, Jiho; Lee, Jayoung; Park, Dahl; Kim, Wontaek; Ki, Yongkan; Kim, Ho Kyung

    2015-07-01

    One of the emerging issues in radiography is low-dose imaging to minimize patient's exposure. The scintillating materials employed in most indirect flat-panel detectors show a drastic change of X-ray photon absorption efficiency around their K-edge energies that consequently affects image quality. Using various tube voltages, we investigated the imaging performance of most popular scintillators: cesium iodide (CsI) and gadolinium oxysulfide (Gd2O2S). The integrated detective quantum efficiencies (iDQE) of four detectors installed in the same hospital were evaluated according to the standardized procedure IEC 62220-1 at tube voltages of 40 - 120 kVp. The iDQE values of the Gd2O2S detectors were normalized by those of CsI detectors to exclude the effects of image postprocessing. The contrast-to-noise ratios (CNR) were also evaluated by using an anthropomorphic chest phantom. The iDQE of the CsI detector outperformed that of the Gd2O2S detector over all tube voltages. Moreover, we noted that the iDQE of the Gd2O2S detectors quickly rolled off with decreasing tube voltage under 70 kVp. The CNRs of the two scintillators were similar at 120 kVp. At 60 kVp, however, the CNR of Gd2O2S was about half that of CsI. Compared to the Gd2O2S detectors, variations in the DQE performance of the CsI detectors were relatively immune to variations in the applied tube voltages. Therefore, we claim that Gd2O2S detectors are inappropriate for use in low-tube-voltage imaging (e.g., extremities and pediatrics) with low patient exposure.

  5. The design and imaging characteristics of dynamic, solid-state, flat-panel x-ray image detectors for digital fluoroscopy and fluorography

    International Nuclear Information System (INIS)

    Cowen, A.R.; Davies, A.G.; Sivananthan, M.U.

    2008-01-01

    Dynamic, flat-panel, solid-state, x-ray image detectors for use in digital fluoroscopy and fluorography emerged at the turn of the millennium. This new generation of dynamic detectors utilize a thin layer of x-ray absorptive material superimposed upon an electronic active matrix array fabricated in a film of hydrogenated amorphous silicon (a-Si:H). Dynamic solid-state detectors come in two basic designs, the indirect-conversion (x-ray scintillator based) and the direct-conversion (x-ray photoconductor based). This review explains the underlying principles and enabling technologies associated with these detector designs, and evaluates their physical imaging characteristics, comparing their performance against the long established x-ray image intensifier television (TV) system. Solid-state detectors afford a number of physical imaging benefits compared with the latter. These include zero geometrical distortion and vignetting, immunity from blooming at exposure highlights and negligible contrast loss (due to internal scatter). They also exhibit a wider dynamic range and maintain higher spatial resolution when imaging over larger fields of view. The detective quantum efficiency of indirect-conversion, dynamic, solid-state detectors is superior to that of both x-ray image intensifier TV systems and direct-conversion detectors. Dynamic solid-state detectors are playing a burgeoning role in fluoroscopy-guided diagnosis and intervention, leading to the displacement of x-ray image intensifier TV-based systems. Future trends in dynamic, solid-state, digital fluoroscopy detectors are also briefly considered. These include the growth in associated three-dimensional (3D) visualization techniques and potential improvements in dynamic detector design

  6. Usefulness of DICOM headers in the analysis of two biplane X-ray systems setting (image intensifier and flat panel) used in pediatric interventional cardiology in Chile

    International Nuclear Information System (INIS)

    Ubeda, C.; Vergara, F.

    2009-01-01

    The setting of two biplane X ray systems were evaluated (image intensifier (II) and flat panel (PP)), through DICOM tags from 32 images created during the characterization of both systems. The technical parameters adjusted for systems were: 63,8 to 80,0 kV and 15,0 to 388,0 mA, for the system with II and 52,0 to 77,0 kV and 25,0 to 476,0 mA, for the system with PP detector. Both equipment presented a different mA adjustment, when moving from fluoroscopy modes low dose (FL), medium dose (FM) and high dose (FH) to cine mode (CI). Two dosimetric quantities were evaluated, the first one was the dose-area product (DAP) which gave as a result for FB mode, between 0,03 to 0,35 uGycm 2 /image (II) and from 0,05 a 0,69 uGycm 2 /image (PP), when the polymethyl methacrylate (PMMA) thickness was incremented from 4 to 16 cm. In cine mode the DAP quantity showed, percentage values from 24 to -1 % for the same PMMA increment. Skin cumulative dose was the second quantity evaluated and showed an increment of incident air kerma (KAI)/image in factors from 17 to 35 (II) and 15 to 28 (PP) when used in CI mode instead of FB mode, to the different PMMA thicknesses used. This dose increment for CI mode must be considered by cardiologists, to use the fluoroscopic run as an alternative to document part of the procedures when there is no need to use a high quality image (author)

  7. Performance of a static-anode/flat-panel x-ray fluoroscopy system in a diagnostic strength magnetic field: a truly hybrid x-ray/MR imaging system.

    Science.gov (United States)

    Fahrig, R; Wen, Z; Ganguly, A; DeCrescenzo, G; Rowlands, J A; Stevens, G M; Saunders, R F; Pelc, N J

    2005-06-01

    Minimally invasive procedures are increasing in variety and frequency, facilitated by advances in imaging technology. Our hybrid imaging system (GE Apollo flat panel, custom Brand x-ray static anode x-ray tube, GE Lunar high-frequency power supply and 0.5 T Signa SP) provides both x-ray and MR imaging capability to guide complex procedures without requiring motion of the patient between two distant gantries. The performance of the x-ray tube in this closely integrated system was evaluated by modeling and measuring both the response of the filament to an externally applied field and the behavior of the electron beam for field strengths and geometries of interest. The performance of the detector was assessed by measuring the slanted-edge modulation transfer function (MTF) and when placed at zero field and at 0.5 T. Measured resonant frequencies of filaments can be approximated using a modified vibrating beam model, and were at frequencies well below the 25 kHz frequency of our generator for our filament geometry. The amplitude of vibration was not sufficient to cause shorting of the filament during operation within the magnetic field. A simple model of electrons in uniform electric and magnetic fields can be used to estimate the deflection of the electron beam on the anode for the fields of interest between 0.2 and 0.5 T. The MTF measured at the detector and the DQE showed no significant difference inside and outside of the magnetic field. With the proper modifications, an x-ray system can be fully integrated with a MR system, with minimal loss of image quality. Any x-ray tube can be assessed for compatibility when placed at a particular location within the field using the models. We have also concluded that a-Si electronics are robust against magnetic fields. Detailed knowledge of the x-ray system installation is required to provide estimates of system operation.

  8. Detection of small pulmonary nodules on chest radiographs: efficacy of dual-energy subtraction technique using flat-panel detector chest radiography

    International Nuclear Information System (INIS)

    Oda, S.; Awai, K.; Funama, Y.; Utsunomiya, D.; Yanaga, Y.; Kawanaka, K.; Nakaura, T.; Hirai, T.; Murakami, R.; Nomori, H.; Yamashita, Y.

    2010-01-01

    Aim: To investigate the effect of a double-exposure dual-energy subtraction (DES) technique on the diagnostic performance of radiologists detecting small pulmonary nodules on flat-panel detector (FPD) chest radiographs. Materials and methods: Using FPD radiography 41 sets of chest radiographs were obtained from 26 patients with pulmonary nodules measuring ≤20 mm and from 15 normal participants. Each dataset included standard and corresponding DES images. There were six non-solid, 10 part-solid, and 10 solid nodules. The mean size of the 26 nodules was 15 ± 4.8 mm. Receiver operating characteristic (ROC) analysis was performed to compare the performance of the eight board-certified radiologists. Results: For the eight radiologists, the mean value of the area under the ROC curve (AUC) without and with DES images was 0.62 ± 0.05 and 0.68 ± 0.05, respectively; the difference was statistically significant (p = 0.02). For part-solid nodules, the difference of the mean AUC value was statistically significant (AUC = 0.61 ± 0.07 versus 0.69 ± 0.05; p < 0.01); for non-solid nodules it was not (AUC = 0.62 ± 0.1 versus 0.61 ± 0.09; p = 0.73), and for solid nodules it was not (AUC = 0.75 ± 0.1 versus 0.78 ± 0.08; p = 0.23). For nodules with overlapping bone shadows, the difference of the mean AUC value was statistically significant (p = 0.03), for nodules without overlapping, it was not (p = 0.26). Conclusion: Use of a double-exposure DES technique at FPD chest radiography significantly improved the diagnostic performance of radiologists to detect small pulmonary nodules.

  9. Comparison of Radiation Exposure during Endovascular Treatment of Peripheral Arterial Disease with Flat-Panel Detectors on Mobile C-arm versus Fixed Systems.

    Science.gov (United States)

    Guillou, Marie; Maurel, Blandine; Necib, Hatem; Vent, Pierre-Alexandre; Costargent, Alain; Chaillou, Philippe; Gouëffic, Yann; Kaladji, Adrien

    2018-02-01

    Flat-panel detectors on mobile C-arm (MC-arm) systems are currently challenging fixed C-arm (FC-arm) systems used in hybrid operating rooms. MC-arm systems offer an alternative to FC-arm systems in the endovascular treatment of peripheral arterial disease (PAD) but their efficiency has not been evaluated comparatively. Two series of patients undergoing arteriography with intention to treat were included. Each series consisted of 2 nonrandomized groups: an MC-arm group and an FC-arm group. Series 1 evaluated exposure to the patient (MC-arm, n = 113; FC-arm, n = 206) while series 2 evaluated exposure to patients and also health care personnel (MC-arm, n = 24; FC-arm, n = 76). The primary end points for evaluating exposure were air kerma (AK, in mGy) for patients and effective dose for health care personnel (in μSv). After adjustment for the effect of body mass index (analysis of covariance test), AK was found to be lower in the MC-arm group than in the FC-arm group (124.1 ± 142 vs. 173.3 ± 248.7, P = 0.025). There was no difference between the groups with regard to effective dose recorded for senior surgeons or for operating room nurses. However, a higher effective dose was recorded by the MC-arm group external dosimeter for the trainee resident and for nurse anesthetists. In endovascular treatment of lower limb PAD, use of an FC-arm system is associated with more radiation exposure to the patient than an MC-arm system. However, this type of imaging system does not appear to affect exposure to health care personnel. Copyright © 2017 Elsevier Inc. All rights reserved.

  10. High-EPA Biomass from Nannochloropsis salina Cultivated in a Flat-Panel Photo-Bioreactor on a Process Water-Enriched Growth Medium

    Directory of Open Access Journals (Sweden)

    Hamed Safafar

    2016-07-01

    Full Text Available Nannochloropsis salina was grown on a mixture of standard growth media and pre-gasified industrial process water representing effluent from a local biogas plant. The study aimed to investigate the effects of enriched growth media and cultivation time on nutritional composition of Nannochloropsis salina biomass, with a focus on eicosapentaenoic acid (EPA. Variations in fatty acid composition, lipids, protein, amino acids, tocopherols and pigments were studied and results compared to algae cultivated on F/2 media as reference. Mixed growth media and process water enhanced the nutritional quality of Nannochloropsis salina in laboratory scale when compared to algae cultivated in standard F/2 medium. Data from laboratory scale translated to the large scale using a 4000 L flat panel photo-bioreactor system. The algae growth rate in winter conditions in Denmark was slow, but results revealed that large-scale cultivation of Nannochloropsis salina at these conditions could improve the nutritional properties such as EPA, tocopherol, protein and carotenoids compared to laboratory-scale cultivated microalgae. EPA reached 44.2% ± 2.30% of total fatty acids, and α-tocopherol reached 431 ± 28 µg/g of biomass dry weight after 21 days of cultivation. Variations in chemical compositions of Nannochloropsis salina were studied during the course of cultivation. Nannochloropsis salina can be presented as a good candidate for winter time cultivation in Denmark. The resulting biomass is a rich source of EPA and also a good source of protein (amino acids, tocopherols and carotenoids for potential use in aquaculture feed industry.

  11. Investigation on effect of image lag in fluoroscopic images obtained with a dynamic flat-panel detector (FPD) on accuracy of target tracking in radiotherapy

    International Nuclear Information System (INIS)

    Tanaka, Rie; Ichikawa, Katsuhiro; Sanada, Sigeru; Mori, Shinichiro; Dobashi, Suguru; Kumagai, Motoki; Minohara, Shinichi; Kawashima, Hiroki

    2010-01-01

    Real-time tumor tracking in external radiotherapy can be achieved by diagnostic (kV) X-ray imaging with a dynamic flat-panel detector (FPD). The purpose of this study was to address image lag in target tracking and its influence on the accuracy of tumor tracking. Fluoroscopic images were obtained using a direct type of dynamic FPD. Image lag properties were measured without test devices according to IEC 62220-1. Modulation transfer function (MTF) and profile curves were measured on the edges of a moving tungsten plate at movement rate of 10 and 20 mm/s, covering lung tumor movement of normal breathing. A lung tumor and metal sphere with blurred edge due to image lag was simulated using the results and then superimposed on breathing chest radiographs of a patient. The moving target with and without image lag was traced using a template-matching technique. In the results, the image lag for the first frame after X-ray cutoff was 2.0% and decreased to less than 0.1% in the fifth frame. In the measurement of profile curves on the edges of static and moving tungsten material plates, the effect of image lag was seen as blurred edges of the plate. The blurred edges of a moving target were indicated as reduction of MTF. However, the target could be traced within an error of ±5 mm. The results indicated that there was no effect of image lag on target tracking in usual breathing speed in a radiotherapy situation. (author)

  12. Performance of a static-anode/flat-panel x-ray fluoroscopy system in a diagnostic strength magnetic field: A truly hybrid x-ray/MR imaging system

    International Nuclear Information System (INIS)

    Fahrig, R.; Wen, Z.; Ganguly, A.; DeCrescenzo, G.; Rowlands, J.A.; Stevens, G.M.; Saunders, R.F.; Pelc, N.J.

    2005-01-01

    Minimally invasive procedures are increasing in variety and frequency, facilitated by advances in imaging technology. Our hybrid imaging system (GE Apollo TM flat panel, custom Brand x-ray static anode x-ray tube, GE Lunar high-frequency power supply and 0.5 T Signa SP TM ) provides both x-ray and MR imaging capability to guide complex procedures without requiring motion of the patient between two distant gantries. The performance of the x-ray tube in this closely integrated system was evaluated by modeling and measuring both the response of the filament to an externally applied field and the behavior of the electron beam for field strengths and geometries of interest. The performance of the detector was assessed by measuring the slanted-edge modulation transfer function (MTF) and when placed at zero field and at 0.5 T. Measured resonant frequencies of filaments can be approximated using a modified vibrating beam model, and were at frequencies well below the 25 kHz frequency of our generator for our filament geometry. The amplitude of vibration was not sufficient to cause shorting of the filament during operation within the magnetic field. A simple model of electrons in uniform electric and magnetic fields can be used to estimate the deflection of the electron beam on the anode for the fields of interest between 0.2 and 0.5 T. The MTF measured at the detector and the DQE showed no significant difference inside and outside of the magnetic field. With the proper modifications, an x-ray system can be fully integrated with a MR system, with minimal loss of image quality. Any x-ray tube can be assessed for compatibility when placed at a particular location within the field using the models. We have also concluded that a-Si electronics are robust against magnetic fields. Detailed knowledge of the x-ray system installation is required to provide estimates of system operation

  13. Noise variance analysis using a flat panel x-ray detector: A method for additive noise assessment with application to breast CT applications

    Energy Technology Data Exchange (ETDEWEB)

    Yang Kai; Huang, Shih-Ying; Packard, Nathan J.; Boone, John M. [Department of Radiology, University of California, Davis Medical Center, 4860 Y Street, Suite 3100 Ellison Building, Sacramento, California 95817 (United States); Department of Radiology, University of California, Davis Medical Center, 4860 Y Street, Suite 3100 Ellison Building, Sacramento, California 95817 (United States) and Department of Biomedical Engineering, University of California, Davis, Davis, California, 95616 (United States)

    2010-07-15

    Purpose: A simplified linear model approach was proposed to accurately model the response of a flat panel detector used for breast CT (bCT). Methods: Individual detector pixel mean and variance were measured from bCT projection images acquired both in air and with a polyethylene cylinder, with the detector operating in both fixed low gain and dynamic gain mode. Once the coefficients of the linear model are determined, the fractional additive noise can be used as a quantitative metric to evaluate the system's efficiency in utilizing x-ray photons, including the performance of different gain modes of the detector. Results: Fractional additive noise increases as the object thickness increases or as the radiation dose to the detector decreases. For bCT scan techniques on the UC Davis prototype scanner (80 kVp, 500 views total, 30 frames/s), in the low gain mode, additive noise contributes 21% of the total pixel noise variance for a 10 cm object and 44% for a 17 cm object. With the dynamic gain mode, additive noise only represents approximately 2.6% of the total pixel noise variance for a 10 cm object and 7.3% for a 17 cm object. Conclusions: The existence of the signal-independent additive noise is the primary cause for a quadratic relationship between bCT noise variance and the inverse of radiation dose at the detector. With the knowledge of the additive noise contribution to experimentally acquired images, system modifications can be made to reduce the impact of additive noise and improve the quantum noise efficiency of the bCT system.

  14. Variation in X-ray dose quantity using an amorphous selenium based flat-panel detector - a study on the dose reduction rate up to the limit of diagnostical utilization

    International Nuclear Information System (INIS)

    Lehnert, T.; Wohlers, J.; Manegold, K.; Wetter, A.; Jacobi, V.; Mack, M.G.; Vogl, T.J.; Streng, W.

    2006-01-01

    Purpose: To evaluate the diagnostic quality and minimum required dose to obtain acceptable images for diagnostic purposes in the field of musculoskeletal radiology. Materials and methods: A critical comparison of the image quality produced by a novel flat panel detector and the conventional screen/film system using a contrast-detail phantom was performed in phase I. Images from both systems were obtained with the same dose and displayed with similar contrast and density. In phase II images of significant anatomical structures in cadaver extremities obtained using the digital detector system and the standard film/screen system were critically evaluated. After a successive reduction in the X-ray dose for 84 patients in phase III, eight independent radiologists compared the image quality of the screen/film system to that of the novel flat panel detector. Results: Phases I and II revealed a difference in the image quality achieved by the standard screen/film system and the digital detector system to the advantage of the digital detector system. In 77 of 84 patients (91.7%), phase III showed equal image quality after a 50% reduction in the X-ray dose. In 3 cases (3.6%) the image quality and the level of contrast were better. No unified statement could be made for 4 patients (4.7%). Conclusion: Digital imaging of skeletal disorders using the novel flat panel detector makes it possible to reduce the X-ray dose by 50% with equal or even better image quality. (orig.)

  15. Volumetric breast density estimation from full-field digital mammograms.

    Science.gov (United States)

    van Engeland, Saskia; Snoeren, Peter R; Huisman, Henkjan; Boetes, Carla; Karssemeijer, Nico

    2006-03-01

    A method is presented for estimation of dense breast tissue volume from mammograms obtained with full-field digital mammography (FFDM). The thickness of dense tissue mapping to a pixel is determined by using a physical model of image acquisition. This model is based on the assumption that the breast is composed of two types of tissue, fat and parenchyma. Effective linear attenuation coefficients of these tissues are derived from empirical data as a function of tube voltage (kVp), anode material, filtration, and compressed breast thickness. By employing these, tissue composition at a given pixel is computed after performing breast thickness compensation, using a reference value for fatty tissue determined by the maximum pixel value in the breast tissue projection. Validation has been performed using 22 FFDM cases acquired with a GE Senographe 2000D by comparing the volume estimates with volumes obtained by semi-automatic segmentation of breast magnetic resonance imaging (MRI) data. The correlation between MRI and mammography volumes was 0.94 on a per image basis and 0.97 on a per patient basis. Using the dense tissue volumes from MRI data as the gold standard, the average relative error of the volume estimates was 13.6%.

  16. Integrated radiotherapy imaging system (IRIS): design considerations of tumour tracking with linac gantry-mounted diagnostic x-ray systems with flat-panel detectors.

    Science.gov (United States)

    Berbeco, Ross I; Jiang, Steve B; Sharp, Gregory C; Chen, George T; Mostafavi, Hassan; Shirato, Hiroki

    2004-01-21

    The design of an integrated radiotherapy imaging system (IRIS), consisting of gantry mounted diagnostic (kV) x-ray tubes and fast read-out flat-panel amorphous-silicon detectors, has been studied. The system is meant to be capable of three main functions: radiographs for three-dimensional (3D) patient set-up, cone-beam CT and real-time tumour/marker tracking. The goal of the current study is to determine whether one source/panel pair is sufficient for real-time tumour/marker tracking and, if two are needed, the optimal position of each relative to other components and the isocentre. A single gantry-mounted source/imager pair is certainly capable of the first two of the three functions listed above and may also be useful for the third, if combined with prior knowledge of the target's trajectory. This would be necessary because only motion in two dimensions is visible with a single imager/source system. However, with previously collected information about the trajectory, the third coordinate may be derived from the other two with sufficient accuracy to facilitate tracking. This deduction of the third coordinate can only be made if the 3D tumour/marker trajectory is consistent from fraction to fraction. The feasibility of tumour tracking with one source/imager pair has been theoretically examined here using measured lung marker trajectory data for seven patients from multiple treatment fractions. The patients' selection criteria include minimum mean amplitudes of the tumour motions greater than 1 cm peak-to-peak. The marker trajectory for each patient was modelled using the first fraction data. Then for the rest of the data, marker positions were derived from the imager projections at various gantry angles and compared with the measured tumour positions. Our results show that, due to the three dimensionality and irregular trajectory characteristics of tumour motion, on a fraction-to-fraction basis, a 'monoscopic' system (single source/imager) is inadequate for

  17. Normalized noise power spectrum of full field digital mammography detector system

    International Nuclear Information System (INIS)

    Norriza Mohd Isa; Wan Muhamad Saridan Wan Hassan

    2009-01-01

    Full text: A method to measure noise power spectrum of a full field digital mammography system is presented. The effect of X-ray radiation dose, size and configuration of region of interest on normalized noise power spectrum (NNPS) was investigated. Flat field images were acquired using RQA-M2 beam quality technique (Mo/Mo anode-filter, 28 kV, 2 mm Al) with different clinical radiation doses. The images were cropped at about 4 cm from the edge of the breast wall and then divided into different size of non-overlapping or overlapping segments. NNPS was determined through de trending, 2-D fast Fourier transformation and normalization. Our measurement shows that high radiation dose gave lower NNPS at a specific beam quality. (author)

  18. Spectral analysis of full field digital mammography data

    International Nuclear Information System (INIS)

    Heine, John J.; Velthuizen, Robert P.

    2002-01-01

    The spectral content of mammograms acquired from using a full field digital mammography (FFDM) system are analyzed. Fourier methods are used to show that the FFDM image power spectra obey an inverse power law; in an average sense, the images may be considered as 1/f fields. Two data representations are analyzed and compared (1) the raw data, and (2) the logarithm of the raw data. Two methods are employed to analyze the power spectra (1) a technique based on integrating the Fourier plane with octave ring sectioning developed previously, and (2) an approach based on integrating the Fourier plane using rings of constant width developed for this work. Both methods allow theoretical modeling. Numerical analysis indicates that the effects due to the transformation influence the power spectra measurements in a statistically significant manner in the high frequency range. However, this effect has little influence on the inverse power law estimation for a given image regardless of the data representation or the theoretical analysis approach. The analysis is presented from two points of view (1) each image is treated independently with the results presented as distributions, and (2) for a given representation, the entire image collection is treated as an ensemble with the results presented as expected values. In general, the constant ring width analysis forms the foundation for a spectral comparison method for finding spectral differences, from an image distribution sense, after applying a nonlinear transformation to the data. The work also shows that power law estimation may be influenced due to the presence of noise in the higher frequency range, which is consistent with the known attributes of the detector efficiency. The spectral modeling and inverse power law determinations obtained here are in agreement with that obtained from the analysis of digitized film-screen images presented previously. The form of the power spectrum for a given image is approximately 1/f 2

  19. Optimization of exposure parameters in full field digital mammography

    International Nuclear Information System (INIS)

    Williams, Mark B.; Raghunathan, Priya; More, Mitali J.; Seibert, J. Anthony; Kwan, Alexander; Lo, Joseph Y.; Samei, Ehsan; Ranger, Nicole T.; Fajardo, Laurie L.; McGruder, Allen; McGruder, Sandra M.; Maidment, Andrew D. A.; Yaffe, Martin J.; Bloomquist, Aili; Mawdsley, Gordon E.

    2008-01-01

    Optimization of exposure parameters (target, filter, and kVp) in digital mammography necessitates maximization of the image signal-to-noise ratio (SNR), while simultaneously minimizing patient dose. The goal of this study is to compare, for each of the major commercially available full field digital mammography (FFDM) systems, the impact of the selection of technique factors on image SNR and radiation dose for a range of breast thickness and tissue types. This phantom study is an update of a previous investigation and includes measurements on recent versions of two of the FFDM systems discussed in that article, as well as on three FFDM systems not available at that time. The five commercial FFDM systems tested, the Senographe 2000D from GE Healthcare, the Mammomat Novation DR from Siemens, the Selenia from Hologic, the Fischer Senoscan, and Fuji's 5000MA used with a Lorad M-IV mammography unit, are located at five different university test sites. Performance was assessed using all available x-ray target and filter combinations and nine different phantom types (three compressed thicknesses and three tissue composition types). Each phantom type was also imaged using the automatic exposure control (AEC) of each system to identify the exposure parameters used under automated image acquisition. The figure of merit (FOM) used to compare technique factors is the ratio of the square of the image SNR to the mean glandular dose. The results show that, for a given target/filter combination, in general FOM is a slowly changing function of kVp, with stronger dependence on the choice of target/filter combination. In all cases the FOM was a decreasing function of kVp at the top of the available range of kVp settings, indicating that higher tube voltages would produce no further performance improvement. For a given phantom type, the exposure parameter set resulting in the highest FOM value was system specific, depending on both the set of available target/filter combinations, and

  20. Volume CT with a flat-panel detector on a mobile, isocentric C-arm: Pre-clinical investigation in guidance of minimally invasive surgery

    International Nuclear Information System (INIS)

    Siewerdsen, J.H.; Moseley, D.J.; Burch, S.; Bisland, S.K.; Bogaards, A.; Wilson, B.C.; Jaffray, D.A.

    2005-01-01

    A mobile isocentric C-arm (Siemens PowerMobil) has been modified in our laboratory to include a large area flat-panel detector (in place of the x-ray image intensifier), providing multi-mode fluoroscopy and cone-beam computed tomography (CT) imaging capability. This platform represents a promising technology for minimally invasive, image-guided surgical procedures where precision in the placement of interventional tools with respect to bony and soft-tissue structures is critical. The image quality and performance in surgical guidance was investigated in pre-clinical evaluation in image-guided spinal surgery. The control, acquisition, and reconstruction system are described. The reproducibility of geometric calibration, essential to achieving high three-dimensional (3D) image quality, is tested over extended time scales (7 months) and across a broad range in C-arm angulation (up to 45 deg.), quantifying the effect of improper calibration on spatial resolution, soft-tissue visibility, and image artifacts. Phantom studies were performed to investigate the precision of 3D localization (viz., fiber optic probes within a vertebral body) and effect of lateral projection truncation (limited field of view) on soft-tissue detectability in image reconstructions. Pre-clinical investigation was undertaken in a specific spinal procedure (photodynamic therapy of spinal metastases) in five animal subjects (pigs). In each procedure, placement of fiber optic catheters in two vertebrae (L1 and L2) was guided by fluoroscopy and cone-beam CT. Experience across five procedures is reported, focusing on 3D image quality, the effects of respiratory motion, limited field of view, reconstruction filter, and imaging dose. Overall, the intraoperative cone-beam CT images were sufficient for guidance of needles and catheters with respect to bony anatomy and improved surgical performance and confidence through 3D visualization and verification of transpedicular trajectories and tool placement

  1. SU-E-I-11: Cascaded Linear System Model for Columnar CsI Flat Panel Imagers with Depth Dependent Gain and Blur

    International Nuclear Information System (INIS)

    Peng, B; Lubinsky, A; Zheng, H; Zhao, W; Teymurazyan, A

    2014-01-01

    Purpose: To implement a depth dependent gain and blur cascaded linear system model (CLSM) for optimizing columnar structured CsI indirect conversion flat panel imager (FPI) for advanced imaging applications. Methods: For experimental validation, depth dependent escape efficiency, e(z), was extracted from PHS measurement of different CsI scintillators (thickness, substrate and light output). The inherent MTF and DQE of CsI was measured using high resolution CMOS sensor. For CLSM, e(z) and the depth dependent MTF(f,z), were estimated using Monte Carlo simulation (Geant4) of optical photon transport through columnar CsI. Previous work showed that Monte Carlo simulation for CsI was hindered by the non-ideality of its columnar structure. In the present work we allowed variation in columnar width with depth, and assumed diffusive reflective backing and columns. Monte Carlo simulation was performed using an optical point source placed at different depth of the CsI layer, from which MTF(z,f) and e(z) were computed. The resulting e(z) with excellent matching with experimental measurements were then applied to the CLSM, Monte Carlo simulation was repeated until the modeled MTF, DQE(f) also match experimental measurement. Results: For a 150 micron FOS HL type CsI, e(z) varies between 0.56 to 0.45, and the MTF at 14 cycles/mm varies between 62.1% to 3.9%, from the front to the back of the scintillator. The overall MTF and DQE(f) at all frequencies are in excellent agreement with experimental measurements at all frequencies. Conclusion: We have developed a CLSM for columnar CsI scintillators with depth dependent gain and MTF, which were estimated from Monte Carlo simulation with novel optical simulation settings. Preliminary results showed excellent agreement between simulation results and experimental measurements. Future work is aimed at extending this approach to optimize CsI screen optic design and sensor structure for achieving higher DQE(f) in cone-beam CT, which uses

  2. Performance evaluation of a direct-conversion flat-panel detector system in imaging and quality assurance for a high-dose-rate 192Ir source

    Science.gov (United States)

    Miyahara, Yoshinori; Hara, Yuki; Nakashima, Hiroto; Nishimura, Tomonori; Itakura, Kanae; Inomata, Taisuke; Kitagaki, Hajime

    2018-03-01

    In high-dose-rate (HDR) brachytherapy, a direct-conversion flat-panel detector (d-FPD) clearly depicts a 192Ir source without image halation, even under the emission of high-energy gamma rays. However, it was unknown why iridium is visible when using a d-FPD. The purpose of this study was to clarify the reasons for visibility of the source core based on physical imaging characteristics, including the modulation transfer functions (MTF), noise power spectral (NPS), contrast transfer functions, and linearity of d-FPD to high-energy gamma rays. The acquired data included: x-rays, [X]; gamma rays, [γ] dual rays (X  +  γ), [D], and subtracted data for depicting the source ([D]  -  [γ]). In the quality assurance (QA) test for the positional accuracy of a source core, the coordinates of each dwelling point were compared between the planned and actual source core positions using a CT/MR-compatible ovoid applicator and a Fletcher-Williamson applicator. The profile curves of [X] and ([D]  -  [γ]) matched well on MTF and NPS. The contrast resolutions of [D] and [X] were equivalent. A strongly positive linear correlation was found between the output data of [γ] and source strength (r 2  >  0.99). With regard to the accuracy of the source core position, the largest coordinate difference (3D distance) was noted at the maximum curvature of the CT/MR-compatible ovoid and Fletcher-Williamson applicators, showing 1.74  ±  0.02 mm and 1.01  ±  0.01 mm, respectively. A d-FPD system provides high-quality images of a source, even when high-energy gamma rays are emitted to the detector, and positional accuracy tests with clinical applicators are useful in identifying source positions (source movements) within the applicator for QA.

  3. Psychophysical evaluation of the image quality of a dynamic flat-panel digital x-ray image detector using the threshold contrast detail detectability (TCDD) technique

    Science.gov (United States)

    Davies, Andrew G.; Cowen, Arnold R.; Bruijns, Tom J. C.

    1999-05-01

    We are currently in an era of active development of the digital X-ray imaging detectors that will serve the radiological communities in the new millennium. The rigorous comparative physical evaluations of such devices are therefore becoming increasingly important from both the technical and clinical perspectives. The authors have been actively involved in the evaluation of a clinical demonstration version of a flat-panel dynamic digital X-ray image detector (or FDXD). Results of objective physical evaluation of this device have been presented elsewhere at this conference. The imaging performance of FDXD under radiographic exposure conditions have been previously reported, and in this paper a psychophysical evaluation of the FDXD detector operating under continuous fluoroscopic conditions is presented. The evaluation technique employed was the threshold contrast detail detectability (TCDD) technique, which enables image quality to be measured on devices operating in the clinical environment. This approach addresses image quality in the context of both the image acquisition and display processes, and uses human observers to measure performance. The Leeds test objects TO[10] and TO[10+] were used to obtain comparative measurements of performance on the FDXD and two digital spot fluorography (DSF) systems, one utilizing a Plumbicon camera and the other a state of the art CCD camera. Measurements were taken at a range of detector entrance exposure rates, namely 6, 12, 25 and 50 (mu) R/s. In order to facilitate comparisons between the systems, all fluoroscopic image processing such as noise reduction algorithms, were disabled during the experiments. At the highest dose rate FDXD significantly outperformed the DSF comparison systems in the TCDD comparisons. At 25 and 12 (mu) R/s all three-systems performed in an equivalent manner and at the lowest exposure rate FDXD was inferior to the two DSF systems. At standard fluoroscopic exposures, FDXD performed in an equivalent

  4. The x-ray time of flight method for investigation of ghosting in amorphous selenium-based flat panel medical x-ray imagers

    International Nuclear Information System (INIS)

    Rau, A.W.; Bakueva, L.; Rowlands, J.A.

    2005-01-01

    Amorphous selenium (a-Se) based real-time flat-panel imagers (FPIs) are finding their way into the digital radiology department because they offer the practical advantages of digital x-ray imaging combined with an image quality that equals or outperforms that of conventional systems. The temporal imaging characteristics of FPIs can be affected by ghosting (i.e., radiation-induced changes of sensitivity) when the dose to the detector is high (e.g., portal imaging and mammography) or the images are acquired at a high frame rate (e.g., fluoroscopy). In this paper, the x-ray time-of-flight (TOF) method is introduced as a tool for the investigation of ghosting in a-Se photoconductor layers. The method consists of irradiating layers of a-Se with short x-ray pulses. From the current generated in the a-Se layer, ghosting is quantified and the ghosting parameters (charge carrier generation rate and carrier lifetimes and mobilities) are assessed. The x-ray TOF method is novel in that (1) x-ray sensitivity (S) and ghosting parameters can be measured simultaneously (2) the transport of both holes and electrons can be isolated, and (3) the method is applicable to the practical a-Se layer structure with blocking contacts used in FPIs. The x-ray TOF method was applied to an analysis of ghosting in a-Se photoconductor layers under portal imaging conditions, i.e., 1 mm thick a-Se layers, biased at 5 V/μm, were irradiated using a 6 MV LINAC x-ray beam to a total dose (ghosting dose) of 30 Gy. The initial sensitivity (S 0 ) of the a-Se layers was 63±2 nC cm -2 cGy -1 . It was found that S decreases to 30% of S 0 after a ghosting dose of 5 Gy and to 21% after 30 Gy at which point no further change in S occurs. At an x-ray intensity of 22 Gy/s (instantaneous dose rate during a LINAC x-ray pulse), the charge carrier generation rate was 1.25±0.1x10 22 ehp m -3 s -1 and, to a first approximation, independent of the ghosting dose. However, both hole and electron transport showed a

  5. An investigation of signal performance enhancements achieved through innovative pixel design across several generations of indirect detection, active matrix, flat-panel arrays

    International Nuclear Information System (INIS)

    Antonuk, Larry E.; Zhao Qihua; El-Mohri, Youcef; Du Hong; Wang Yi; Street, Robert A.; Ho, Jackson; Weisfield, Richard; Yao, William

    2009-01-01

    Active matrix flat-panel imager (AMFPI) technology is being employed for an increasing variety of imaging applications. An important element in the adoption of this technology has been significant ongoing improvements in optical signal collection achieved through innovations in indirect detection array pixel design. Such improvements have a particularly beneficial effect on performance in applications involving low exposures and/or high spatial frequencies, where detective quantum efficiency is strongly reduced due to the relatively high level of additive electronic noise compared to signal levels of AMFPI devices. In this article, an examination of various signal properties, as determined through measurements and calculations related to novel array designs, is reported in the context of the evolution of AMFPI pixel design. For these studies, dark, optical, and radiation signal measurements were performed on prototype imagers incorporating a variety of increasingly sophisticated array designs, with pixel pitches ranging from 75 to 127 μm. For each design, detailed measurements of fundamental pixel-level properties conducted under radiographic and fluoroscopic operating conditions are reported and the results are compared. A series of 127 μm pitch arrays employing discrete photodiodes culminated in a novel design providing an optical fill factor of ∼80% (thereby assuring improved x-ray sensitivity), and demonstrating low dark current, very low charge trapping and charge release, and a large range of linear signal response. In two of the designs having 75 and 90 μm pitches, a novel continuous photodiode structure was found to provide fill factors that approach the theoretical maximum of 100%. Both sets of novel designs achieved large fill factors by employing architectures in which some, or all of the photodiode structure was elevated above the plane of the pixel addressing transistor. Generally, enhancement of the fill factor in either discrete or continuous

  6. st Tomosynthesis Plus Full Field Digital Mammography or Full Field Digital Mammography Alone in the Screening Environment

    Directory of Open Access Journals (Sweden)

    Stamatia Destounis

    2014-01-01

    Full Text Available Objectives: Initial review of patients undergoing screening mammography imaged with a combination of digital breast tomosynthesis (DBT plus full field digital mammography (FFDM compared with FFDM alone. Materials and Methods: From June 2011 to December 2011, all patients presenting for routine screening mammography were offered a combination DBT plus FFDM exam. Under institutional review board approval, we reviewed 524 patients who opted for combination DBT plus FFDM and selected a sample group of 524 FFDM screening exams from the same time period for a comparative analysis. The χ2 (Chi-square test was used to compare recall rates, breast density, personal history of breast cancer, and family history of breast cancer between the two groups. Results: Recall rate for FFDM, 11.45%, was significantly higher (P < 0001 than in the combination DBT plus FFDM group (4.20%. The biopsy rate in the FFDM group was 2.29% (12/524, with a cancer detection rate of 0.38% (2/524, or 3.8 per 1000 and positive predictive value (PPV of 16.7% (2/12. The biopsy rate for the DBT plus FFDM group was 1.14% (n = 6/524, with a cancer detection rate 0.57% (n = 3/524, or 5.7 per 1000 and PPV of 50.0% (n = 3/6. Personal history of breast cancer in the FFDM group was significantly lower (P < 0.0001 than in the combination DBT plus FFDM group; 2.5% and 5.7%, respectively. A significant difference in family history of breast cancer (P < 0.0001 was found, with a higher rate in the combination DBT plus FFDM group (36.0% vs. 53.8%. There was a significant difference between the combination DBT plus FFDM group and FFDM alone group, when comparing breast density (P < 0.0147, 61.64% vs. 54.20% dense breasts, respectively with a higher rate of dense breasts in the DBT plus FFDM group. In follow-up, one cancer was detected within one year of normal screening mammogram in the combination DBT plus FFDM group. Conclusion: Our initial experience found the recall rate in the combination DBT

  7. Design, development, manufacture, testing, and delivery of devices for connection of solar cell panel circuitry to flat conductor cable solar cell array harness

    Science.gov (United States)

    Dillard, P. A.; Waddington, D.

    1971-01-01

    The technology status and problem areas which exist for the application of flat conductor cabling to solar cell arrays are summarized. Details covering the design, connector manufacture, and prototype test results are also summarized.

  8. Preliminary evaluation of a prototype stereoscopic a-Si:H-based X-ray imaging system for full-field digital mammography

    International Nuclear Information System (INIS)

    Darambara, D.G.; Speller, R.D.; Horrocks, J.A.; Godber, S.; Wilson, R.; Hanby, A.

    2001-01-01

    In a pre-clinical study, we have been investigating the potential of a-Si:H active matrix, flat panel imagers for X-ray full-field digital mammography through the development of an advanced 3D X-ray imaging system and have measured a number of their important imaging characteristics. To enhance the information embodied into the digital images produced by the a-Si array, stereoscopic images, created by viewing the object under examination from two angles and recombining the images, were obtained. This method provided us with a full 3D X-ray image of the test object as well as left and right perspective 2D images all at the same time. Within this scope, images of fresh, small human breast tissue specimens--normal and diseased--were obtained at ±2 deg., processed and stereoscopically displayed for a pre-clinical evaluation by radiologists. It was demonstrated that the stereoscopic presentation of the images provides important additional information and has potential benefits over the more traditional 2D data

  9. Clinical evaluation of digital radiography based on a large-area cesium iodide-amorphous silicon flat-panel detector compared with screen-film radiography for skeletal system and abdomen

    International Nuclear Information System (INIS)

    Okamura, Terue; Tanaka, Saori; Koyama, Koichi; Norihumi, Nishida; Daikokuya, Hideo; Matsuoka, Toshiyuki; Yamada, Ryusaku; Kishimoto, Kenji; Hatagawa, Masakatsu; Kudoh, Hiroaki

    2002-01-01

    The aim of this clinical study was to compare the image quality of digital radiography using the new digital Bucky system based on a flat-panel detector with that of a conventional screen-film system for the skeletal structure and the abdomen. Fifty patients were examined using digital radiography with a flat-panel detector and screen-film systems, 25 for the skeletal structures and 25 for the abdomen. Six radiologists judged each paired image acquired under the same exposure parameters concerning three observation items for the bone and six items for the abdomen. Digital radiographic images for the bone were evaluated to be similar to screen-film images at the mean of 42.2%, to be superior at 50.2%, and to be inferior at 7.6%. Digital radiographic images for the abdomen were judged to be similar to screen-film images at the mean of 43.4%, superior at 52.4%, and inferior at 4.2%; thus, digital radiographic images were estimated to be either similar as or superior to screen-film images at over 92% for the bone and abdomen. On the statistical analysis, digital radiographic images were also judged to be preferred significantly in the most items for the bone and abdomen. In conclusion, the image quality of digital radiography with a flat-panel detector was superior to that of a screen-film system under the same exposure parameters, suggesting that dose reduction is possible with digital radiography. (orig.)

  10. Development of Surfaces Optically Suitable for Flat Solar Panels. [using a reflectometer which separately evaluates spectral and diffuse reflectivities of surfaces

    Science.gov (United States)

    1979-01-01

    A reflectometer which can separately evaluate the spectral and diffuse reflectivities of surfaces is described. A phase locked detection system for the reflectometer is also described. A selective coating on aluminum potentially useful for flat plate solar collector applications is presented. The coating is composed of strongly bound copper oxide (divalent) and is formed by an etching process performed on an aluminum alloy with high copper content. Fabrication costs are expected to be small due to the one stop fabrication process. A number of conclusions gathered from the literature as to the required optical properties of flat plate solar collectors are discussed.

  11. Comparison of dose and image quality of a Flat-panel detector and an image intensifier; Comparacao da dose e qualidade da imagem de um detector Flatpanel e um intensificador de imagem

    Energy Technology Data Exchange (ETDEWEB)

    Lazzaro, M.; Friedrich, B.Q.; Luz, R.M. da; Silva, A.M.M. da, E-mail: marcos.lazzaro@acad.pucrs.br [Pontificia Universidade Catolica do Rio Grande do Sul (PUC-RS), Porto Alegre, RS (Brazil)

    2016-07-01

    With the development of new technologies, have emerged new conversion methods of X-ray image, such as flat panel detectors. The aim of this work is the comparison of entrance surface air kerma (ESAK) and image quality between an image intensifier type of detector (A) and a flat panel (B). The ESAK was obtained by placing a ionization chamber under PMMA simulators of 10, 20 and 30 cm and the image quality was obtained by using the TOR {sup 18}FG simulator. The ESAK to the equipment A is higher when compared to the equipment B. The high contrast resolution is better for the equipment A for all thicknesses of simulators. The equipment A has low contrast resolution with a better viewing threshold for thicknesses of 10 and 20 cm, and a worse performance for 30 cm. It is concluded that the equipment B has ESAK smaller and despite having lower resolution, in almost all cases, have appropriate image quality for diagnosis. (author)

  12. Dose reduction of radiographs of the pediatric pelvis for diagnosing hip dysplasia using a digital flat-panel detector system; Dosisreduktion bei Roentgenaufnahmen des kindlichen Beckenskelettes zur Diagnostik der Hueftgelenksdysplasie unter Verwendung eines digitalen Flachdetektorsystems

    Energy Technology Data Exchange (ETDEWEB)

    Ludwig, K.; Ahlers, K.; Kloska, S.; Vieth, V.; Meier, N.; Heindel, W. [Inst. fuer Klinische Radiologie, Westfaelische Wilhelms-Univ. Muenster (Germany); Sandmann, C.; Gosheger, G. [Orthopaedische Klinik, Westfaelische Wilhelms-Univ. Muenster (Germany)

    2003-01-01

    Purpose: To evaluate a possible dose reduction in pediatric pelvic radiographs in congenital hip dysplasia using a digital flat-panel system instead of a phosphor-storage system. Materials and Methods: During a six-month period, all pediatric patients referred for pelvic radiography for the evaluation of congenital hip dysplasia were randomely assigned to be examined by either a phosphor-storage system or a digital flat-panel system, whereby the latter system was operated with half the radiation dose. Thirty pairs of radiographs were assessed for the visibility of 16 anatomic details and for 5 orthopedic-radiographic measurements (5-point scale with 1 = excellent; three independent observers). The projection indices of Ball and Kommenda and of Toennis and Brunken were calculated for all radiographs. The Student's t-test was used to compare the flat-panel and the phosphor-storage radiographs for observers' assessments, patients' age and projection indices. Results: In a total of 7560 observations, the scores for the visibility of anatomic details and orthopedic-radiographic measurements were respectively 2.72 and 2.64 for the flat-panel system and 2.93 and 2.79 for the phosphor-storage system. No significant differences were found between both systems (p > 0.05) and between patient age and projection indices (p > 0.05). Conclusion: Pediatric pelvic radiographs can be obtained with a digital flat-panel system using half the radiation dose instead of a phosphor-storage system without sacrificing relevant information in the diagnosis of congenital hip dysplasia. (orig.) [German] Zielsetzung: Evaluation einer moeglichen Dosisreduktion bei kindlichen Beckenroentgenaufnahmen zur Diagnostik der Hueftgelenksdysplasie mit einem digitalen Flachdetektorsystem im Vergleich zu einem digitalen Speicherfoliensystem. Material und Methoden: Prospektiv wurden alle ueber einen Zeitraum von 6 Monaten zur Roentgenaufnahme des Beckenskelettes im Rahmen der Diagnostik der

  13. Suspicious amorphous microcalcifications detected on full-field digital mammography: correlation with histopathology

    Directory of Open Access Journals (Sweden)

    Vera Christina Camargo de Siqueira Ferreira

    2018-03-01

    Full Text Available Abstract Objective: To evaluate suspicious amorphous calcifications diagnosed on full-field digital mammography (FFDM and establish correlations with histopathology findings. Materials and Methods: This was a retrospective study of 78 suspicious amorphous calcifications (all classified as BI-RADS® 4 detected on FFDM. Vacuum-assisted breast biopsy (VABB was performed. The histopathological classification of VABB core samples was as follows: pB2 (benign; pB3 (uncertain malignant potential; pB4 (suspicion of malignancy; and pB5 (malignant. Treatment was recommended for pB5 lesions. To rule out malignancy, surgical excision was recommended for pB3 and pB4 lesions. Patients not submitted to surgery were followed for at least 6 months. Results: Among the 78 amorphous calcifications evaluated, the histopathological analysis indicated that 8 (10.3% were malignant/suspicious (6 classified as pB5 and 2 classified as pB4 and 36 (46.2% were benign (classified as pB2. The remaining 34 lesions (43.6% were classified as pB3: 33.3% were precursor lesions (atypical ductal hyperplasia, lobular neoplasia, or flat epithelial atypia and 10.3% were high-risk lesions. For the pB3 lesions, the underestimation rate was zero. Conclusion: The diagnosis of precursor lesions (excluding atypical ductal hyperplasia, which can be pB4 depending on the severity and extent of the lesion should not necessarily be considered indicative of underestimation of malignancy. Suspicious amorphous calcifications correlated more often with precursor lesions than with malignant lesions, at a ratio of 3:1.

  14. Aging and characterization of PVC compound used as flat-panel of a low cost solar collector; Envelhecimento e caracterizacao de compostos de PVC usado em placas de coletores solares de baixo custo

    Energy Technology Data Exchange (ETDEWEB)

    Prado, Bruna R.; Pinto, Tatiana T.; Bartoli, Julio R. [Depto. de Tecnologia de Polimeros, Faculdade de Engenharia Quimica/Universidade Estadual de Campinas. FEQ/UNICAMP, SP (Brazil)], e-mail: bartoli@feq.unicamp.br; Fernandes, Elizabeth G. [Tezca P and D Celulas Solares (Brazil)

    2011-07-01

    Regardless the excellent amount of solar irradiation in Brazil, the development and production of solar water heating systems did not reach the low-income families yet. The relatively high cost of conventional solar water heaters is still the main reason to prevent it. The development of a low cost solar water heater (around US$ 200), easy technology, was the scope of previous work. All-plastic solar collector prototypes were developed using unplasticized Poly (vinyl chloride) ceiling panels and tubes, commodities from building engineering. Nevertheless, the main thermal and photo degradation mechanisms for PVC are well known; the unusual application of PVC as solar collector materials should need a specific investigation on environmental aging. This work presents a study on outdoor aging and characterization of PVC flat-plate absorber of solar collectors after 5 years on use. (author)

  15. Comparison between radiation exposure levels using an image intensifier and a flat-panel detector-based system in image-guided central venous catheter placement in children weighing less than 10 kg

    Energy Technology Data Exchange (ETDEWEB)

    Miraglia, Roberto; Maruzzelli, Luigi; Cortis, Kelvin; Gerasia, Roberta; Maggio, Simona; Luca, Angelo [Diagnostic and Therapeutic Services, Mediterranean Institute for Transplantation and Advanced Specialized Therapies (ISMETT), Palermo (Italy); Piazza, Marcello [Department of Anesthesia, Mediterranean Institute for Transplantation and Advanced Specialized Therapies (ISMETT), Palermo (Italy); Tuzzolino, Fabio [Department of Information Technology, Mediterranean Institute for Transplantation and Advanced Specialized Therapies (ISMETT), Palermo (Italy)

    2014-09-10

    Ultrasound-guided central venous puncture and fluoroscopic guidance during central venous catheter (CVC) positioning optimizes technical success and lowers the complication rates in children, and is therefore considered standard practice. The purpose of this study was to compare the radiation exposure levels recorded during CVC placement in children weighing less than 10 kg in procedures performed using an image intensifier-based angiographic system (IIDS) to those performed in a flat-panel detector-based interventional suite (FPDS). A retrospective review of 96 image-guided CVC placements, between January 2008 and October 2013, in 49 children weighing less than 10 kg was performed. Mean age was 8.2 ± 4.4 months (range: 1-22 months). Mean weight was 7.1 ± 2.7 kg (range: 2.5-9.8 kg). The procedures were classified into two categories: non-tunneled and tunneled CVC placement. Thirty-five procedures were performed with the IIDS (21 non-tunneled CVC, 14 tunneled CVC); 61 procedures were performed with the FPDS (47 non-tunneled CVC, 14 tunneled CVC). For non-tunneled CVC, mean DAP was 113.5 ± 126.7 cGy cm{sup 2} with the IIDS and 15.9 ± 44.6 cGy . cm{sup 2} with the FPDS (P < 0.001). For tunneled CVC, mean DAP was 84.6 ± 81.2 cGy . cm{sup 2} with the IIDS and 37.1 ± 33.5 cGy cm{sup 2} with the FPDS (P = 0.02). The use of flat-panel angiographic equipment reduces radiation exposure in small children undergoing image-guided CVC placement. (orig.)

  16. Comparison of scatter rejection and low-contrast performance of scan equalization digital radiography (SEDR), slot-scan digital radiography, and full-field digital radiography systems for chest phantom imaging

    Energy Technology Data Exchange (ETDEWEB)

    Liu Xinming; Shaw, Chris C.; Lai, Chao-Jen; Wang Tianpeng [Department of Imaging Physics, Digital Imaging Research Laboratory, University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030-4009 (United States)

    2011-01-15

    Purpose: To investigate and compare the scatter rejection properties and low-contrast performance of the scan equalization digital radiography (SEDR) technique to the slot-scan and conventional full-field digital radiography techniques for chest imaging. Methods: A prototype SEDR system was designed and constructed with an a-Se flat-panel (FP) detector to improve image quality in heavily attenuating regions of an anthropomorphic chest phantom. Slot-scanning geometry was used to reject scattered radiation without attenuating primary x rays. The readout scheme of the FP was modified to erase accumulated scatter signals prior to image readout. A 24-segment beam width modulator was developed to regulate x-ray exposures regionally and compensate for the low x-ray flux in heavily attenuating regions. To measure the scatter-to-primary ratios (SPRs), a 2 mm thick lead plate with a 2-D array of aperture holes was used to measure the primary signals, which were then subtracted from those obtained without the lead plate to determine scatter components. A 2-D array of aluminum beads (3 mm in diameter) was used as the low-contrast objects to measure the contrast ratios (CRs) and contrast-to-noise ratios (CNRs) for evaluating the low-contrast performance in chest phantom images. A set of two images acquired with the same techniques were subtracted from each other to measure the noise levels. SPRs, CRs, and CNRs of the SEDR images were measured in four anatomical regions of chest phantom images and compared to those of slot-scan images and full-field images acquired with and without antiscatter grid. Results: The percentage reduction of SPR (percentage of SPRs reduced with scatter removal/rejection methods relative to that for nongrid full-field imaging) averaged over four anatomical regions was measured to be 80%, 83%, and 71% for SEDR, slot-scan, and full-field with grid, respectively. The average CR over four regions was found to improve over that for nongrid full-field

  17. Comparison of scatter rejection and low-contrast performance of scan equalization digital radiography (SEDR), slot-scan digital radiography, and full-field digital radiography systems for chest phantom imaging

    International Nuclear Information System (INIS)

    Liu Xinming; Shaw, Chris C.; Lai, Chao-Jen; Wang Tianpeng

    2011-01-01

    Purpose: To investigate and compare the scatter rejection properties and low-contrast performance of the scan equalization digital radiography (SEDR) technique to the slot-scan and conventional full-field digital radiography techniques for chest imaging. Methods: A prototype SEDR system was designed and constructed with an a-Se flat-panel (FP) detector to improve image quality in heavily attenuating regions of an anthropomorphic chest phantom. Slot-scanning geometry was used to reject scattered radiation without attenuating primary x rays. The readout scheme of the FP was modified to erase accumulated scatter signals prior to image readout. A 24-segment beam width modulator was developed to regulate x-ray exposures regionally and compensate for the low x-ray flux in heavily attenuating regions. To measure the scatter-to-primary ratios (SPRs), a 2 mm thick lead plate with a 2-D array of aperture holes was used to measure the primary signals, which were then subtracted from those obtained without the lead plate to determine scatter components. A 2-D array of aluminum beads (3 mm in diameter) was used as the low-contrast objects to measure the contrast ratios (CRs) and contrast-to-noise ratios (CNRs) for evaluating the low-contrast performance in chest phantom images. A set of two images acquired with the same techniques were subtracted from each other to measure the noise levels. SPRs, CRs, and CNRs of the SEDR images were measured in four anatomical regions of chest phantom images and compared to those of slot-scan images and full-field images acquired with and without antiscatter grid. Results: The percentage reduction of SPR (percentage of SPRs reduced with scatter removal/rejection methods relative to that for nongrid full-field imaging) averaged over four anatomical regions was measured to be 80%, 83%, and 71% for SEDR, slot-scan, and full-field with grid, respectively. The average CR over four regions was found to improve over that for nongrid full-field

  18. Scintillator high-gain avalanche rushing photoconductor active-matrix flat panel imager: zero-spatial frequency x-ray imaging properties of the solid-state SHARP sensor structure.

    Science.gov (United States)

    Wronski, M; Zhao, W; Tanioka, K; Decrescenzo, G; Rowlands, J A

    2012-11-01

    The authors are investigating the feasibility of a new type of solid-state x-ray imaging sensor with programmable avalanche gain: scintillator high-gain avalanche rushing photoconductor active matrix flat panel imager (SHARP-AMFPI). The purpose of the present work is to investigate the inherent x-ray detection properties of SHARP and demonstrate its wide dynamic range through programmable gain. A distributed resistive layer (DRL) was developed to maintain stable avalanche gain operation in a solid-state HARP. The signal and noise properties of the HARP-DRL for optical photon detection were investigated as a function of avalanche gain both theoretically and experimentally, and the results were compared with HARP tube (with electron beam readout) used in previous investigations of zero spatial frequency performance of SHARP. For this new investigation, a solid-state SHARP x-ray image sensor was formed by direct optical coupling of the HARP-DRL with a structured cesium iodide (CsI) scintillator. The x-ray sensitivity of this sensor was measured as a function of avalanche gain and the results were compared with the sensitivity of HARP-DRL measured optically. The dynamic range of HARP-DRL with variable avalanche gain was investigated for the entire exposure range encountered in radiography∕fluoroscopy (R∕F) applications. The signal from HARP-DRL as a function of electric field showed stable avalanche gain, and the noise associated with the avalanche process agrees well with theory and previous measurements from a HARP tube. This result indicates that when coupled with CsI for x-ray detection, the additional noise associated with avalanche gain in HARP-DRL is negligible. The x-ray sensitivity measurements using the SHARP sensor produced identical avalanche gain dependence on electric field as the optical measurements with HARP-DRL. Adjusting the avalanche multiplication gain in HARP-DRL enabled a very wide dynamic range which encompassed all clinically relevant

  19. Scintillator high-gain avalanche rushing photoconductor active-matrix flat panel imager: Zero-spatial frequency x-ray imaging properties of the solid-state SHARP sensor structure

    International Nuclear Information System (INIS)

    Wronski, M.; Zhao, W.; Tanioka, K.; DeCrescenzo, G.; Rowlands, J. A.

    2012-01-01

    Purpose: The authors are investigating the feasibility of a new type of solid-state x-ray imaging sensor with programmable avalanche gain: scintillator high-gain avalanche rushing photoconductor active matrix flat panel imager (SHARP-AMFPI). The purpose of the present work is to investigate the inherent x-ray detection properties of SHARP and demonstrate its wide dynamic range through programmable gain. Methods: A distributed resistive layer (DRL) was developed to maintain stable avalanche gain operation in a solid-state HARP. The signal and noise properties of the HARP-DRL for optical photon detection were investigated as a function of avalanche gain both theoretically and experimentally, and the results were compared with HARP tube (with electron beam readout) used in previous investigations of zero spatial frequency performance of SHARP. For this new investigation, a solid-state SHARP x-ray image sensor was formed by direct optical coupling of the HARP-DRL with a structured cesium iodide (CsI) scintillator. The x-ray sensitivity of this sensor was measured as a function of avalanche gain and the results were compared with the sensitivity of HARP-DRL measured optically. The dynamic range of HARP-DRL with variable avalanche gain was investigated for the entire exposure range encountered in radiography/fluoroscopy (R/F) applications. Results: The signal from HARP-DRL as a function of electric field showed stable avalanche gain, and the noise associated with the avalanche process agrees well with theory and previous measurements from a HARP tube. This result indicates that when coupled with CsI for x-ray detection, the additional noise associated with avalanche gain in HARP-DRL is negligible. The x-ray sensitivity measurements using the SHARP sensor produced identical avalanche gain dependence on electric field as the optical measurements with HARP-DRL. Adjusting the avalanche multiplication gain in HARP-DRL enabled a very wide dynamic range which encompassed all

  20. Comparison of Photopic Negative Response of Full-Field and Focal Electroretinograms in Detecting Glaucomatous Eyes

    Directory of Open Access Journals (Sweden)

    Shigeki Machida

    2011-01-01

    Full Text Available Purpose. To compare the photopic negative response (PhNR of the full-field electroretinogram (ERG to the PhNR of the focal ERGs in detecting glaucoma. Methods. One hundred and three eyes with glaucoma and 42 normal eyes were studied. Full-field ERGs were elicited by red stimuli on a blue background. The focal ERGs were elicited by a 15∘ white stimulus spot centered on the macula, the superotemporal or the inferotemporal areas of the macula. Results. In early glaucoma, the areas under the receiver operating characteristic curves (AUCs were significantly larger for the focal PhNR (0.863–0.924 than those for the full-field PhNR (0.666–0.748 (P<.05. The sensitivity was significantly higher for the focal PhNR than for the full-field PhNR in early (P<.01 and intermediate glaucoma (P<.05. In advanced glaucoma, there was no difference in the AUCs and sensitivities between the focal and full-field PhNRs. Conclusions. The focal ERG has the diagnostic ability with higher sensitivity in detecting early and intermediate glaucoma than the full-field ERG.

  1. Non-destructive, preclinical evaluation of root canal anatomy of human teeth with flat-panel detector volume CT (FD-VCT); Zerstoerungsfreie praeklinische Evaluation der Wurzelkanalanatomie menschlicher Zaehne mittels Flaechendetektor-Volumen-CT (FD-VCT)

    Energy Technology Data Exchange (ETDEWEB)

    Heidrich, G.; Hassepass, F.; Dullin, C.; Grabbe, E. [Universitaetsklinikum Goettingen, Abt. Diagnostische Radiologie (Germany); Attin, T.; Hannig, C. [Universitaetsklinikum Goettingen, Abt. fuer Zahnerhaltung, Praeventive Zahnheilkunde und Paradontologie (Germany)

    2005-12-15

    Purpose: Successful endodontic diagnostics and therapy call for adequate depiction of the root canal anatomy with multimodal diagnostic imaging. The aim of the present study is to evaluate visualization of the endodont with flat-panel detector volume CT (FD-VCT). Materials and methods: 13 human teeth were examined with the prototype of a FD-VCT. After data acquisition and generation of volume data sets in volume rendering technology (VRT), the findings obtained were compared to conventional X-rays and cross-section preparations of the teeth. Results: The anatomical structures of the endodont such as root canals, side canals and communications between different root canals as well as dentricles could be detected precisely with FD-VCT. The length of curved root canals was also determined accurately. The spatial resolution of the system is around 140 {mu}m. Only around 73% of the main root canals detected with FD-VCT and 87% of the roots could be visualized with conventional dental X-rays. None of the side canals, shown with FD-VCT, was detectable on conventional X-rays. In all cases the enamel and dentin of the teeth could be well delineated. No differences in image quality could be discerned between stored and freshly extracted teeth, or between primary and adult teeth. (orig.)

  2. The Virtual Fields Method Extracting Constitutive Mechanical Parameters from Full-field Deformation Measurements

    CERN Document Server

    Pierron, Fabrice

    2012-01-01

    The Virtual Fields Method: Extracting Constitutive Mechanical Parameters from Full-field Deformation Measurements is the first book on the Virtual Fields Method (VFM), a technique to identify materials mechanical properties from full-field measurements. Firmly rooted with extensive theoretical description of the method, the book presents numerous examples of application to a wide range of materials (composites, metals, welds, biomaterials) and situations (static, vibration, high strain rate). The authors give a detailed training section with examples of progressive difficulty to lead the reader to program the VFM and include a set of commented Matlab programs as well as GUI Matlab-based software for more general situations. The Virtual Fields Method: Extracting Constitutive Mechanical Parameters from Full-field Deformation Measurements is an ideal book for researchers, engineers, and students interested in applying the VFM to new situations motivated by their research.  

  3. A study on 100 MeV O{sup 7+} irradiated SnO{sub 2}/Ag/SnO{sub 2} multilayer as transparent electrode for flat panel display application

    Energy Technology Data Exchange (ETDEWEB)

    Sharma, Vikas [Department of Physics, Malaviya National Institute of Technology, Jaipur 302017 (India); Singh, Satyavir, E-mail: satyavir84@gmail.com [Department of Physics, Malaviya National Institute of Technology, Jaipur 302017 (India); Asokan, K. [Inter-University Accelerator Centre, Aruna Asaf Ali Road, New Delhi 110067 (India); Sachdev, Kanupriya [Department of Physics, Malaviya National Institute of Technology, Jaipur 302017 (India); Materials Research Centre, Malaviya National Institute of Technology, Jaipur 302017 India (India)

    2016-07-15

    The multilayer thin films of SnO{sub 2}/Ag/SnO{sub 2} were deposited using electron-beam and thermal evaporation for flat panel display application. The as-prepared SnO{sub 2}/Ag/SnO{sub 2} specimen was irradiated with 100 MeV O{sup 7+} ions by varying the fluences 1 × 10{sup 12} and 5 × 10{sup 12} ions/cm{sup 2}. The pristine and irradiated films were investigated using XRD, SEM, AFM and Raman to find out modification in the structure and surface morphology of the films. UV–Vis and Hall measurement techniques were used to investigate the optical and electrical properties respectively. It was observed that the roughness of the film after irradiation (for the fluence of 1 × 10{sup 12} ions/cm{sup 2}) ​ decreased to 0.68 nm from 1.6 nm and showed an increase in roughness to 1.35 nm on increasing the fluence to 5 × 10{sup 12} ions/cm{sup 2}. This oxide/metal/oxide structure fulfills the basic requirements of a TCE, like high-transmittance >75% for pristine and >80% for the fluence of 1 × 10{sup 12} ions/cm{sup 2} over a broad spectrum of visible light for practical applications. The multilayer structure shows change in the electrical resistivity from 1.6 × 10{sup −3} Ω cm to 6.3 × 10{sup −3} Ω cm after irradiation.

  4. Should 3K zoom function be used for detection of pneumothorax in cesium iodide/amorphous silicon flat-panel detector radiographs presented on 1K-matrix soft copies?

    International Nuclear Information System (INIS)

    Herrmann, Karin A.; Zech, C.J.; Reiser, M.F.; Bonel, H.M.; Staebler, A.; Voelk, M.; Strotzer, M.

    2006-01-01

    The purpose of the study was to evaluate observer performance in the detection of pneumothorax with cesium iodide and amorphous silicon flat-panel detector radiography (CsI/a-Si FDR) presented as 1K and 3K soft-copy images. Forty patients with and 40 patients without pneumothorax diagnosed on previous and subsequent digital storage phosphor radiography (SPR, gold standard) had follow-up chest radiographs with CsI/a-Si FDR. Four observers confirmed or excluded the diagnosis of pneumothorax according to a five-point scale first on the 1K soft-copy image and then with help of 3K zoom function (1K monitor). Receiver operating characteristic (ROC) analysis was performed for each modality (1K and 3K). The area under the curve (AUC) values for each observer were 0.7815, 0.7779, 0.7946 and 0.7066 with 1K-matrix soft copies and 0.8123, 0.7997, 0.8078 and 0.7522 with 3K zoom. Overall detection of pneumothorax was better with 3K zoom. Differences between the two display methods were not statistically significant in 3 of 4 observers (p-values between 0.13 and 0.44; observer 4: p=0.02). The detection of pneumothorax with 3K zoom is better than with 1K soft copy but not at a statistically significant level. Differences between both display methods may be subtle. Still, our results indicate that 3K zoom should be employed in clinical practice. (orig.)

  5. Flat-Panel Cone-Beam Ct-Guided Radiofrequency Ablation of Very Small (≤1.5 cm) Liver Tumors: Technical Note on a Preliminary Experience

    Energy Technology Data Exchange (ETDEWEB)

    Cazzato, Roberto Luigi, E-mail: r.cazzato@unicampus.it; Buy, Xavier, E-mail: x.buy@bordeaux.unicancer.fr; Alberti, Nicolas, E-mail: nicoalbertibdx@gmail.com; Fonck, Mariane, E-mail: m.fonk@bordeaux.unicancer.fr [Institut Bergonié 229 Cours de l’Argonne, Department of Radiology (France); Grasso, Rosario Francesco, E-mail: r.grasso@unicampus.it [Università “Campus Bio-Medico di Roma”, Department of Radiology and Diagnostic Imaging (Italy); Palussière, Jean, E-mail: j.palussiere@bordeaux.unicancer.fr [Institut Bergonié 229 Cours de l’Argonne, Department of Radiology (France)

    2015-02-15

    PurposeThe aim of the present study was to investigate the technical feasibility of flat-panel cone-beam CT (CBCT)-guided radiofrequency ablation (RFA) of very small (<1.5 cm) liver tumors.Materials and MethodsPatients included were candidates for hepatic percutaneous RFA as they had single biopsy-proven hepatic tumors sized ≤1.5 cm and poorly defined on ultrasonography. Following apnea induction, unenhanced CBCT scans were acquired and used to deploy the RF electrode with the aid of a virtual navigation system. If the tumor was not clearly identified on the unenhanced CBCT scan, a right retrograde arterial femoral access was established to carry out hepatic angiography and localize the tumor. Patients’ lesions and procedural variables were recorded and analyzed.ResultsThree patients (2 male and 1 female), aged 68, 76, and 87 years were included; 3 lesions (2 hepato-cellular carcinoma and 1 metastasis from colorectal cancer) were treated. One patient required hepatic angiography. Cycles of apnea used to acquire CBCT images and to deploy the electrode lasted <120 s. Mean fluoroscopic time needed to deploy the electrode was 36.6 ± 5.7 min. Mean overall procedural time was 66.0 ± 22.9 min. No peri- or post-procedural complications were noted. No cases of incomplete ablation were noted at 1-month follow-up.ConclusionPercutaneous CBCT-guided liver RFA with or without arterial hepatic angiography is technically feasible.

  6. 75 FR 68200 - Medical Devices; Radiology Devices; Reclassification of Full-Field Digital Mammography System

    Science.gov (United States)

    2010-11-05

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration 21 CFR Part 892 [Docket No. FDA-2008-N-0273] Medical Devices; Radiology Devices; Reclassification of Full- Field Digital... and Drugs, 21 CFR part 892 is amended as follows: PART 892--RADIOLOGY DEVICES 0 1. The authority...

  7. Full-field peak pressure prediction of shock waves from underwater explosion of cylindrical charges

    NARCIS (Netherlands)

    Liu, Lei; Guo, Rui; Gao, Ke; Zeng, Ming Chao

    2017-01-01

    Cylindrical charge is a main form in most application of explosives. By employing numerical calculation and an indirect mapping method, the relation between peak pressures from underwater explosion of cylindrical and spherical charges is investigated, and further a model to predict full-field peak

  8. A full-field transmission x-ray microscope for time-resolved imaging of magnetic nanostructures

    Energy Technology Data Exchange (ETDEWEB)

    Ewald, J.; Nisius, T.; Abbati, G.; Baumbach, S.; Overbuschmann, J.; Wilhein, T. [Institute for X-Optics (IXO), Hochschule Koblenz, Joseph-Rovan-Allee 2, 53424 Remagen (Germany); Wessels, P.; Wieland, M.; Drescher, M. [The Hamburg Centre for Ultrafast Imaging (CUI), University of Hamburg, Luruper Chaussee 149, 22761 Hamburg (Germany); Institut für Experimentalphysik, University of Hamburg, Luruper Chaussee 149, 22761 Hamburg (Germany); Vogel, A. [Institut für Angewandte Physik, University of Hamburg, Jungiusstraße 11, 20355 Hamburg (Germany); Viefhaus, J. [Deutsches Elektronen-Synchrotron (DESY), Notkestraße 85, 22607 Hamburg (Germany); Meier, G. [The Hamburg Centre for Ultrafast Imaging (CUI), University of Hamburg, Luruper Chaussee 149, 22761 Hamburg (Germany); Max Planck Institute for the Structure and Dynamics of Matter, Luruper Chaussee 149, 22761 Hamburg (Germany)

    2016-01-28

    Sub-nanosecond magnetization dynamics of small permalloy (Ni{sub 80}Fe{sub 20}) elements has been investigated with a new full-field transmission microscope at the soft X-ray beamline P04 of the high brilliance synchrotron radiation source PETRA III. The soft X-ray microscope generates a flat-top illumination field of 20 μm diameter using a grating condenser. A tilted nanostructured magnetic sample can be excited by a picosecond electric current pulse via a coplanar waveguide. The transmitted light of the sample plane is directly imaged by a micro zone plate with < 65 nm resolution onto a 2D gateable X-ray detector to select one particular bunch in the storage ring that probes the time evolution of the dynamic information successively via XMCD spectromicroscopy in a pump-probe scheme. In the experiments it was possible to generate a homogeneously magnetized state in patterned magnetic layers by a strong magnetic Oersted field pulse of 200 ps duration and directly observe the recovery to the initial flux-closure vortex patterns.

  9. Off-axis full-field swept-source optical coherence tomography using holographic refocusing

    Science.gov (United States)

    Hillmann, Dierck; Franke, Gesa; Hinkel, Laura; Bonin, Tim; Koch, Peter; Hüttmann, Gereon

    2013-03-01

    We demonstrate a full-field swept-source OCT using an off-axis geometry of the reference illumination. By using holographic refocusing techniques, a uniform lateral resolution is achieved over the measurement depth of approximately 80 Rayleigh lengths. Compared to a standard on-axis setup, artifacts and autocorrelation signals are suppressed and the measurement depth is doubled by resolving the complex conjugate ambiguity. Holographic refocusing was done efficiently by Fourier-domain resampling as demonstrated before in inverse scattering and holoscopy. It allowed to reconstruct a complete volume with about 10μm resolution over the complete measurement depth of more than 10mm. Off-axis full-field swept-source OCT enables high measurement depths, spanning many Rayleigh lengths with reduced artifacts.

  10. Measurement of full-field deformation induced by a dc electrical field in organic insulator films

    Directory of Open Access Journals (Sweden)

    Boudou L.

    2010-06-01

    Full Text Available Digital image correlation method (DIC using the correlation coefficient curve-fitting for full-field surface deformation measurements of organic insulator films is investigated in this work. First the validation of the technique was undertaken. The computer-generated speckle images and the measurement of coefficient of thermal expansion (CTE of aluminium are used to evaluate the measurement accuracy of the technique. In a second part the technique is applied to measure the mechanical deformation induced by electrical field application to organic insulators. For that Poly(ethylene naphthalene 2,6-dicarboxylate (PEN thin films were subjected to DC voltage stress and DIC provides the full-field induced deformations of the test films. The obtained results show that the DIC is a practical and robust tool for better comprehension of mechanical behaviour of the organic insulator films under electrical stress.

  11. Viscoelastic material properties' identification using high speed full field measurements on vibrating plates

    Science.gov (United States)

    Giraudeau, A.; Pierron, F.

    2010-06-01

    The paper presents an experimental application of a method leading to the identification of the elastic and damping material properties of isotropic vibrating plates. The theory assumes that the searched parameters can be extracted from curvature and deflection fields measured on the whole surface of the plate at two particular instants of the vibrating motion. The experimental application consists in an original excitation fixture, a particular adaptation of an optical full-field measurement technique, a data preprocessing giving the curvature and deflection fields and finally in the identification process using the Virtual Fields Method (VFM). The principle of the deflectometry technique used for the measurements is presented. First results of identification on an acrylic plate are presented and compared to reference values. Details about a new experimental arrangement, currently in progress, is presented. It uses a high speed digital camera to over sample the full-field measurements.

  12. Transmission X-ray microscopy for full-field nano-imaging of biomaterials

    Science.gov (United States)

    ANDREWS, JOY C; MEIRER, FLORIAN; LIU, YIJIN; MESTER, ZOLTAN; PIANETTA, PIERO

    2010-01-01

    Imaging of cellular structure and extended tissue in biological materials requires nanometer resolution and good sample penetration, which can be provided by current full-field transmission X-ray microscopic techniques in the soft and hard X-ray regions. The various capabilities of full-field transmission X-ray microscopy (TXM) include 3D tomography, Zernike phase contrast, quantification of absorption, and chemical identification via X-ray fluorescence and X-ray absorption near edge structure (XANES) imaging. These techniques are discussed and compared in light of results from imaging of biological materials including microorganisms, bone and mineralized tissue and plants, with a focus on hard X-ray TXM at ≤ 40 nm resolution. PMID:20734414

  13. Transmission X-ray microscopy for full-field nano imaging of biomaterials.

    Science.gov (United States)

    Andrews, Joy C; Meirer, Florian; Liu, Yijin; Mester, Zoltan; Pianetta, Piero

    2011-07-01

    Imaging of cellular structure and extended tissue in biological materials requires nanometer resolution and good sample penetration, which can be provided by current full-field transmission X-ray microscopic techniques in the soft and hard X-ray regions. The various capabilities of full-field transmission X-ray microscopy (TXM) include 3D tomography, Zernike phase contrast, quantification of absorption, and chemical identification via X-ray fluorescence and X-ray absorption near edge structure imaging. These techniques are discussed and compared in light of results from the imaging of biological materials including microorganisms, bone and mineralized tissue, and plants, with a focus on hard X-ray TXM at ≤ 40-nm resolution. Copyright © 2010 Wiley-Liss, Inc.

  14. Full-field wrist pulse signal acquisition and analysis by 3D Digital Image Correlation

    Science.gov (United States)

    Xue, Yuan; Su, Yong; Zhang, Chi; Xu, Xiaohai; Gao, Zeren; Wu, Shangquan; Zhang, Qingchuan; Wu, Xiaoping

    2017-11-01

    Pulse diagnosis is an essential part in four basic diagnostic methods (inspection, listening, inquiring and palpation) in traditional Chinese medicine, which depends on longtime training and rich experience, so computerized pulse acquisition has been proposed and studied to ensure the objectivity. To imitate the process that doctors using three fingertips with different pressures to feel fluctuations in certain areas containing three acupoints, we established a five dimensional pulse signal acquisition system adopting a non-contacting optical metrology method, 3D digital image correlation, to record the full-field displacements of skin fluctuations under different pressures. The system realizes real-time full-field vibration mode observation with 10 FPS. The maximum sample frequency is 472 Hz for detailed post-processing. After acquisition, the signals are analyzed according to the amplitude, pressure, and pulse wave velocity. The proposed system provides a novel optical approach for digitalizing pulse diagnosis and massive pulse signal data acquisition for various types of patients.

  15. Standardized Full-Field Electroretinography in the Green Monkey (Chlorocebus sabaeus)

    DEFF Research Database (Denmark)

    Bouskila, Joseph; Javadi, Pasha; Palmour, Roberta M

    2014-01-01

    Full-field electroretinography is an objective measure of retinal function, serving as an important diagnostic clinical tool in ophthalmology for evaluating the integrity of the retina. Given the similarity between the anatomy and physiology of the human and Green Monkey eyes, this species has......). Photopic and scotopic ERG recordings were obtained by full-field stimulation over a range of 6 log units of intensity in dark-adapted or light-adapted eyes of adult Green Monkeys (Chlorocebus sabaeus). Intensity, duration, and interval of light stimuli were varied separately. Reproducible values...... of amplitude and latency were obtained for the a- and b-waves, under well-controlled adaptation and stimulus conditions; the i-wave was also easily identifiable and separated from the a-b-wave complex in the photopic ERG. The recordings obtained in the healthy Green Monkey matched very well with those...

  16. Full-field transmission-type angle-deviation optical microscope with reflectivity-height transformation.

    Science.gov (United States)

    Chiu, Ming-Hung; Tan, Chen-Tai; Tsai, Ming-Hung; Yang, Ya-Hsin

    2015-10-01

    This full-field transmission-type three-dimensional (3D) optical microscope is constructed based on the angle deviation method (ADM) and the algorithm of reflectivity-height transformation (RHT). The surface height is proportional to the deviation angle of light passing through the object. The angle deviation and surface height can be measured based on the reflectivity closed to the critical angle using a parallelogram prism and two CCDs.

  17. Image processing of full-field strain data and its use in model updating

    International Nuclear Information System (INIS)

    Wang, W; Mottershead, J E; Sebastian, C M; Patterson, E A

    2011-01-01

    Finite element model updating is an inverse problem based on measured structural outputs, typically natural frequencies. Full-field responses such as static stress/strain patterns and vibration mode shapes contain valuable information for model updating but within large volumes of highly-redundant data. Pattern recognition and image processing provide feasible techniques to extract effective and efficient information, often known as shape features, from this data. For instance, the Zernike polynomials having the properties of orthogonality and rotational invariance are powerful decomposition kernels for a shape defined within a unit circle. In this paper, full field strain patterns for a specimen, in the form of a square plate with a circular hole, under a tensile load are considered. Effective shape features can be constructed by a set of modified Zernike polynomials. The modification includes the application of a weighting function to the Zernike polynomials so that high strain magnitudes around the hole are well represented. The Gram-Schmidt process is then used to ensure orthogonality for the obtained decomposition kernels over the domain of the specimen. The difference between full-field strain patterns measured by digital image correlation (DIC) and reconstructed using 15 shape features (Zernike moment descriptors, ZMDs) at different steps in the elasto-plastic deformation of the specimen is found to be very small. It is significant that only a very small number of shape features are necessary and sufficient to represent the full-field data. Model updating of nonlinear elasto-plastic material properties is carried out by adjusting the parameters of a FE model until the FE strain pattern converges upon the measured strains as determined using ZMDs.

  18. Difference in diaphragmatic motion during tidal breathing in a standing position between COPD patients and normal subjects: Time-resolved quantitative evaluation using dynamic chest radiography with flat panel detector system (“dynamic X-ray phrenicography”)

    International Nuclear Information System (INIS)

    Yamada, Yoshitake; Ueyama, Masako; Abe, Takehiko; Araki, Tetsuro; Abe, Takayuki; Nishino, Mizuki; Jinzaki, Masahiro; Hatabu, Hiroto

    2017-01-01

    Highlights: • Dynamic X-ray phrenicography is a useful method for the evaluation of the diaphragms. • Its radiation dose is comparable to conventional two projection chest radiography. • Diaphragm motion during tidal breathing is larger in COPD than in normal subjects. • Higher BMI is also associated with increased excursions of the bilateral diaphragm. - Abstract: Objectives: To quantitatively compare diaphragmatic motion during tidal breathing in a standing position between chronic obstructive pulmonary disease (COPD) patients and normal subjects using dynamic chest radiography. Materials and methods: Thirty-nine COPD patients (35 males; age, 71.3 ± 8.4 years) and 47 normal subjects (non-smoker healthy volunteers) (20 males; age, 54.8 ± 9.8 years) underwent sequential chest radiographs during tidal breathing using dynamic chest radiography with a flat panel detector system. We evaluated the excursions and peak motion speeds of the diaphragms. The results were analyzed using an unpaired t-test and a multiple linear regression model. Results: The excursions of the diaphragms in COPD patients were significantly larger than those in normal subjects (right, 14.7 ± 5.5 mm vs. 10.2 ± 3.7 mm, respectively, P < 0.001; left, 17.2 ± 4.9 mm vs. 14.9 ± 4.2 mm, respectively, P = 0.022). Peak motion speeds in inspiratory phase were significantly faster in COPD patients compared to normal subjects (right, 16.3 ± 5.0 mm/s vs. 11.8 ± 4.2 mm/s, respectively, P < 0.001; left, 18.9 ± 4.9 mm/s vs. 16.7 ± 4.0 mm/s, respectively, P = 0.022). The multivariate analysis demonstrated that having COPD and higher body mass index were independently associated with increased excursions of the bilateral diaphragm (all P < 0.05), after adjusting for other clinical variables. Conclusions: Time-resolved quantitative evaluation of the diaphragm using dynamic chest radiography demonstrated that the diaphragmatic motion during tidal breathing in a standing position is larger and

  19. Time-Resolved Quantitative Analysis of the Diaphragms During Tidal Breathing in a Standing Position Using Dynamic Chest Radiography with a Flat Panel Detector System ("Dynamic X-Ray Phrenicography"): Initial Experience in 172 Volunteers.

    Science.gov (United States)

    Yamada, Yoshitake; Ueyama, Masako; Abe, Takehiko; Araki, Tetsuro; Abe, Takayuki; Nishino, Mizuki; Jinzaki, Masahiro; Hatabu, Hiroto; Kudoh, Shoji

    2017-04-01

    Diaphragmatic motion in a standing position during tidal breathing remains unclear. The purpose of this observational study was to evaluate diaphragmatic motion during tidal breathing in a standing position in a health screening center cohort using dynamic chest radiography in association with participants' demographic characteristics. One hundred seventy-two subjects (103 men; aged 56.3 ± 9.8 years) underwent sequential chest radiographs during tidal breathing using dynamic chest radiography with a flat panel detector system. We evaluated the excursions of and peak motion speeds of the diaphragms. Associations between the excursions and participants' demographics (gender, height, weight, body mass index [BMI], smoking history, tidal volume, vital capacity, and forced expiratory volume) were investigated. The average excursion of the left diaphragm (14.9 ± 4.6 mm, 95% CI 14.2-15.5 mm) was significantly larger than that of the right (11.0 ± 4.0 mm, 95% CI 10.4-11.6 mm) (P <0.001). The peak motion speed of the left diaphragm (inspiratory, 16.6 ± 4.2 mm/s; expiratory, 13.7 ± 4.2 mm/s) was significantly faster than that of the right (inspiratory, 12.4 ± 4.4 mm/s; expiratory, 9.4 ± 3.8 mm/s) (both P <0.001). Both simple and multiple regression models demonstrated that higher BMI and higher tidal volume were associated with increased excursions of the bilateral diaphragm (all P <0.05). The average excursions of the diaphragms are 11.0 mm (right) and 14.9 mm (left) during tidal breathing in a standing position. The diaphragmatic motion of the left is significantly larger and faster than that of the right. Higher BMI and tidal volume are associated with increased excursions of the bilateral diaphragm. Copyright © 2017 The Association of University Radiologists. Published by Elsevier Inc. All rights reserved.

  20. Difference in the craniocaudal gradient of the maximum pixel value change rate between chronic obstructive pulmonary disease patients and normal subjects using sub-mGy dynamic chest radiography with a flat panel detector system.

    Science.gov (United States)

    Yamada, Yoshitake; Ueyama, Masako; Abe, Takehiko; Araki, Tetsuro; Abe, Takayuki; Nishino, Mizuki; Jinzaki, Masahiro; Hatabu, Hiroto; Kudoh, Shoji

    2017-07-01

    To compare the craniocaudal gradients of the maximum pixel value change rate (MPCR) during tidal breathing between chronic obstructive pulmonary disease (COPD) patients and normal subjects using dynamic chest radiography. This prospective study was approved by the institutional review board and all participants provided written informed consent. Forty-three COPD patients (mean age, 71.6±8.7 years) and 47 normal subjects (non-smoker healthy volunteers) (mean age, 54.8±9.8 years) underwent sequential chest radiographs during tidal breathing in a standing position using dynamic chest radiography with a flat panel detector system. We evaluated the craniocaudal gradient of MPCR. The results were analyzed using an unpaired t-test and the Tukey-Kramer method. The craniocaudal gradients of MPCR in COPD patients were significantly lower than those in normal subjects (right inspiratory phase, 75.5±48.1 vs. 108.9±42.0s -1 cm -1 , P<0.001; right expiratory phase, 66.4±40.6 vs. 89.8±31.6s -1 cm -1 , P=0.003; left inspiratory phase, 75.5±48.2 vs. 108.2±47.2s -1 cm -1 , P=0.002; left expiratory phase, 60.9±38.2 vs. 84.3±29.5s -1 cm -1 , P=0.002). No significant differences in height, weight, or BMI were observed between COPD and normal groups. In the sub-analysis, the gradients in severe COPD patients (global initiative for chronic obstructive lung disease [GOLD] 3 or 4, n=26) were significantly lower than those in mild COPD patients (GOLD 1 or 2, n=17) for both right and left inspiratory/expiratory phases (all P≤0.005). A decrease of the craniocaudal gradient of MPCR was observed in COPD patients. The craniocaudal gradient was lower in severe COPD patients than in mild COPD patients. Copyright © 2017 The Author(s). Published by Elsevier B.V. All rights reserved.

  1. SU-E-I-53: Comparison of Kerma-Area-Product Between the Micro-Angiographic Fluoroscope (MAF) and a Flat Panel Detector (FPD) as Used in Neuro-Endovascular Procedures

    International Nuclear Information System (INIS)

    Vijayan, S; Rana, V; Nagesh, S Setlur; Xiong, Z; Rudin, S; Bednarek, D

    2015-01-01

    Purpose: To determine the reduction of integral dose to the patient when using the micro-angiographic fluoroscope (MAF) compared to when using the standard flat-panel detector (FPD) for the techniques used during neurointerventional procedures. Methods: The MAF is a small field-of-view, high resolution x-ray detector which captures 1024 x 1024 pixels with an effective pixel size of 35μm and is capable of real-time imaging up to 30 frames per second. The MAF was used in neuro-interventions during those parts of the procedure when high resolution was needed and the FPD was used otherwise. The technique parameters were recorded when each detector was used and the kerma-area-product (KAP) per image frame was determined. KAP values were calculated for seven neuro interventions using premeasured calibration files of output as a function of kVp and beam filtration and included the attenuation of the patient table for the frontal projections to be more representative of integral patient dose. The air kerma at the patient entrance was multiplied by the beam area at that point to obtain the KAP values. The ranges of KAP values per frame were determined for the range of technique parameters used during the clinical procedures. To appreciate the benefit of the higher MAF resolution in the region of interventional activity, DA technique parameters were generally used with the MAF. Results: The lowest and highest values of KAP per frame for the MAF in DA mode were 4 and 50 times lower, respectively, compared to those of the FPD in pulsed fluoroscopy mode. Conclusion: The MAF was used in those parts of the clinical procedures when high resolution and image quality was essential. The integral patient dose as represented by the KAP value was substantially lower when using the MAF than when using the FPD due to the much smaller volume of tissue irradiated. This research was supported in part by Toshiba Medical Systems Corporation and NIH Grant R01EB002873

  2. A comparison between magnetic resonance angiography at 3 teslas (time-of-flight and contrast-enhanced and flat-panel digital subtraction angiography in the assessment of embolized brain aneurysms

    Directory of Open Access Journals (Sweden)

    Guilherme S. Nakiri

    2011-01-01

    Full Text Available PURPOSE: To compare the time-of-flight and contrast-enhanced- magnetic resonance angiography techniques in a 3 Tesla magnetic resonance unit with digital subtraction angiography with the latest flat-panel technology and 3D reconstruction in the evaluation of embolized cerebral aneurysms. INTRODUCTION: Many embolized aneurysms are subject to a recurrence of intra-aneurismal filling. Traditionally, imaging surveillance of coiled aneurysms has consisted of repeated digital subtraction angiography. However, this method has a small but significant risk of neurological complications, and many authors have advocated the use of noninvasive imaging methods for the surveillance of embolized aneurysms. METHODS: Forty-three aneurysms in 30 patients were studied consecutively between November 2009 and May 2010. Two interventional neuroradiologists rated the time-of-flight-magnetic resonance angiography, the contrast-enhanced-magnetic resonance angiography, and finally the digital subtraction angiography, first independently and then in consensus. The status of aneurysm occlusion was assessed according to the Raymond scale, which indicates the level of recanalization according to degrees: Class 1: excluded aneurysm; Class 2: persistence of a residual neck; Class 3: persistence of a residual aneurysm. The agreement among the analyses was assessed by applying the Kappa statistic. RESULTS: Inter-observer agreement was excellent for both methods (K = 0.93; 95 % CI: 0.84-1. Inter-technical agreement was almost perfect between time-of-flight-magnetic resonance angiography and digital subtraction angiography (K = 0.98; 95 % CI: 0.93-1 and between time-of-flight-magnetic resonance angiography and contrast-enhanced-magnetic resonance angiography (K = 0.98; 95% CI: 0.93-1. Disagreement occurred in only one case (2.3%, which was classified as Class I by time-of-flight-magnetic resonance angiography and Class II by digital subtraction angiography. The agreement between

  3. Difference in diaphragmatic motion during tidal breathing in a standing position between COPD patients and normal subjects: Time-resolved quantitative evaluation using dynamic chest radiography with flat panel detector system (“dynamic X-ray phrenicography”)

    Energy Technology Data Exchange (ETDEWEB)

    Yamada, Yoshitake, E-mail: yamada@rad.med.keio.ac.jp [Department of Radiology, Center for Pulmonary Functional Imaging, Brigham and Women’s Hospital, Harvard Medical School, 75 Francis St., Boston, MA 02215 (United States); Department of Diagnostic Radiology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582 (Japan); Ueyama, Masako, E-mail: ueyamam@fukujuji.org [Department of Health Care, Fukujuji Hospital, Japan Anti-Tuberculosis Association, 3-1-24 Matsuyama, Kiyose, Tokyo 204-8522 (Japan); Abe, Takehiko, E-mail: takehikoabe@hotmail.com [Department of Radiology, Fukujuji Hospital, Japan Anti-Tuberculosis Association, 3-1-24 Matsuyama, Kiyose, Tokyo 204-8522 (Japan); Araki, Tetsuro, E-mail: TARAKI@partners.org [Department of Radiology, Center for Pulmonary Functional Imaging, Brigham and Women’s Hospital, Harvard Medical School, 75 Francis St., Boston, MA 02215 (United States); Abe, Takayuki, E-mail: abe.t@keio.jp [Department of Preventive Medicine and Public Health, Biostatistics Unit at Clinical and Translational Research Center, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582 (Japan); Nishino, Mizuki, E-mail: Mizuki_Nishino11@dfci.harvard.edu [Department of Radiology, Center for Pulmonary Functional Imaging, Brigham and Women’s Hospital, Harvard Medical School, 75 Francis St., Boston, MA 02215 (United States); Jinzaki, Masahiro, E-mail: jinzaki@rad.med.keio.ac.jp [Department of Diagnostic Radiology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582 (Japan); Hatabu, Hiroto, E-mail: hhatabu@partners.org [Department of Radiology, Center for Pulmonary Functional Imaging, Brigham and Women’s Hospital, Harvard Medical School, 75 Francis St., Boston, MA 02215 (United States); and others

    2017-02-15

    Highlights: • Dynamic X-ray phrenicography is a useful method for the evaluation of the diaphragms. • Its radiation dose is comparable to conventional two projection chest radiography. • Diaphragm motion during tidal breathing is larger in COPD than in normal subjects. • Higher BMI is also associated with increased excursions of the bilateral diaphragm. - Abstract: Objectives: To quantitatively compare diaphragmatic motion during tidal breathing in a standing position between chronic obstructive pulmonary disease (COPD) patients and normal subjects using dynamic chest radiography. Materials and methods: Thirty-nine COPD patients (35 males; age, 71.3 ± 8.4 years) and 47 normal subjects (non-smoker healthy volunteers) (20 males; age, 54.8 ± 9.8 years) underwent sequential chest radiographs during tidal breathing using dynamic chest radiography with a flat panel detector system. We evaluated the excursions and peak motion speeds of the diaphragms. The results were analyzed using an unpaired t-test and a multiple linear regression model. Results: The excursions of the diaphragms in COPD patients were significantly larger than those in normal subjects (right, 14.7 ± 5.5 mm vs. 10.2 ± 3.7 mm, respectively, P < 0.001; left, 17.2 ± 4.9 mm vs. 14.9 ± 4.2 mm, respectively, P = 0.022). Peak motion speeds in inspiratory phase were significantly faster in COPD patients compared to normal subjects (right, 16.3 ± 5.0 mm/s vs. 11.8 ± 4.2 mm/s, respectively, P < 0.001; left, 18.9 ± 4.9 mm/s vs. 16.7 ± 4.0 mm/s, respectively, P = 0.022). The multivariate analysis demonstrated that having COPD and higher body mass index were independently associated with increased excursions of the bilateral diaphragm (all P < 0.05), after adjusting for other clinical variables. Conclusions: Time-resolved quantitative evaluation of the diaphragm using dynamic chest radiography demonstrated that the diaphragmatic motion during tidal breathing in a standing position is larger and

  4. SU-D-204-05: Quantitative Comparison of a High Resolution Micro-Angiographic Fluoroscopic (MAF) Detector with a Standard Flat Panel Detector (FPD) Using the New Metric of Generalized Measured Relative Object Detectability (GM-ROD)

    Energy Technology Data Exchange (ETDEWEB)

    Russ, M; Ionita, C; Bednarek, D; Rudin, S [Toshiba Stroke and Vascular Research Center, University at Buffalo (SUNY), Buffalo, NY (United States)

    2015-06-15

    Purpose: In endovascular image-guided neuro-interventions, visualization of fine detail is paramount. For example, the ability of the interventionist to visualize the stent struts depends heavily on the x-ray imaging detector performance. Methods: A study to examine the relative performance of the high resolution MAF-CMOS (pixel size 75µm, Nyquist frequency 6.6 cycles/mm) and a standard Flat Panel Detector (pixel size 194µm, Nyquist frequency 2.5 cycles/mm) detectors in imaging a neuro stent was done using the Generalized Measured Relative Object Detectability (GM-ROD) metric. Low quantum noise images of a deployed stent were obtained by averaging 95 frames obtained by both detectors without changing other exposure or geometric parameters. The square of the Fourier transform of each image is taken and divided by the generalized normalized noise power spectrum to give an effective measured task-specific signal-to-noise ratio. This expression is then integrated from 0 to each of the detector’s Nyquist frequencies, and the GM-ROD value is determined by taking a ratio of the integrals for the MAF-CMOS to that of the FPD. The lower bound of integration can be varied to emphasize high frequencies in the detector comparisons. Results: The MAF-CMOS detector exhibits vastly superior performance over the FPD when integrating over all frequencies, yielding a GM-ROD value of 63.1. The lower bound of integration was stepped up in increments of 0.5 cycles/mm for higher frequency comparisons. As the lower bound increased, the GM-ROD value was augmented, reflecting the superior performance of the MAF-CMOS in the high frequency regime. Conclusion: GM-ROD is a versatile metric that can provide quantitative detector and task dependent comparisons that can be used as a basis for detector selection. Supported by NIH Grant: 2R01EB002873 and an equipment grant from Toshiba Medical Systems Corporation.

  5. SU-E-I-53: Comparison of Kerma-Area-Product Between the Micro-Angiographic Fluoroscope (MAF) and a Flat Panel Detector (FPD) as Used in Neuro-Endovascular Procedures

    Energy Technology Data Exchange (ETDEWEB)

    Vijayan, S; Rana, V; Nagesh, S Setlur; Xiong, Z; Rudin, S; Bednarek, D [Toshiba Stroke and Vascular Research Center, University at Buffalo, Buffalo, NY (United States)

    2015-06-15

    Purpose: To determine the reduction of integral dose to the patient when using the micro-angiographic fluoroscope (MAF) compared to when using the standard flat-panel detector (FPD) for the techniques used during neurointerventional procedures. Methods: The MAF is a small field-of-view, high resolution x-ray detector which captures 1024 x 1024 pixels with an effective pixel size of 35μm and is capable of real-time imaging up to 30 frames per second. The MAF was used in neuro-interventions during those parts of the procedure when high resolution was needed and the FPD was used otherwise. The technique parameters were recorded when each detector was used and the kerma-area-product (KAP) per image frame was determined. KAP values were calculated for seven neuro interventions using premeasured calibration files of output as a function of kVp and beam filtration and included the attenuation of the patient table for the frontal projections to be more representative of integral patient dose. The air kerma at the patient entrance was multiplied by the beam area at that point to obtain the KAP values. The ranges of KAP values per frame were determined for the range of technique parameters used during the clinical procedures. To appreciate the benefit of the higher MAF resolution in the region of interventional activity, DA technique parameters were generally used with the MAF. Results: The lowest and highest values of KAP per frame for the MAF in DA mode were 4 and 50 times lower, respectively, compared to those of the FPD in pulsed fluoroscopy mode. Conclusion: The MAF was used in those parts of the clinical procedures when high resolution and image quality was essential. The integral patient dose as represented by the KAP value was substantially lower when using the MAF than when using the FPD due to the much smaller volume of tissue irradiated. This research was supported in part by Toshiba Medical Systems Corporation and NIH Grant R01EB002873.

  6. Analysis on optical heterodyne frequency error of full-field heterodyne interferometer

    Science.gov (United States)

    Li, Yang; Zhang, Wenxi; Wu, Zhou; Lv, Xiaoyu; Kong, Xinxin; Guo, Xiaoli

    2017-06-01

    The full-field heterodyne interferometric measurement technology is beginning better applied by employing low frequency heterodyne acousto-optical modulators instead of complex electro-mechanical scanning devices. The optical element surface could be directly acquired by synchronously detecting the received signal phases of each pixel, because standard matrix detector as CCD and CMOS cameras could be used in heterodyne interferometer. Instead of the traditional four-step phase shifting phase calculating, Fourier spectral analysis method is used for phase extracting which brings lower sensitivity to sources of uncertainty and higher measurement accuracy. In this paper, two types of full-field heterodyne interferometer are described whose advantages and disadvantages are also specified. Heterodyne interferometer has to combine two different frequency beams to produce interference, which brings a variety of optical heterodyne frequency errors. Frequency mixing error and beat frequency error are two different kinds of inescapable heterodyne frequency errors. In this paper, the effects of frequency mixing error to surface measurement are derived. The relationship between the phase extraction accuracy and the errors are calculated. :: The tolerance of the extinction ratio of polarization splitting prism and the signal-to-noise ratio of stray light is given. The error of phase extraction by Fourier analysis that caused by beat frequency shifting is derived and calculated. We also propose an improved phase extraction method based on spectrum correction. An amplitude ratio spectrum correction algorithm with using Hanning window is used to correct the heterodyne signal phase extraction. The simulation results show that this method can effectively suppress the degradation of phase extracting caused by beat frequency error and reduce the measurement uncertainty of full-field heterodyne interferometer.

  7. Are phantoms useful for predicting the potential of dose reduction in full-field digital mammography?

    International Nuclear Information System (INIS)

    Gennaro, Gisella; Katz, Luc; Souchay, Henri; Alberelli, Claudio; Maggio, Cosimo di

    2005-01-01

    A phantom study was performed in full-field digital mammography to investigate the opportunity and the magnitude of a possible dose reduction that would leave the image quality above the accepted thresholds associated with some classical phantoms. This preliminary work is intended to lay the groundwork for a future clinical study on the impact of dose reduction on clinical results. Three different mammography phantoms (ACR RMI 156, CIRS 11A and CDMAM 3.4) were imaged by a full-field digital mammography unit (GE Senographe 2000D) at different dose levels. Images were rated by three observers with softcopy reading and scoring methods specific to each phantom. Different types of data analysis were applied to the ACR (American College of Radiology) and the other two phantoms, respectively. With reference to the minimum acceptance score in screen/film accreditation programmes, the ACR phantom showed that about 45% dose reduction could be applied, while keeping the phantom scores above that threshold. A relative comparison was done for CIRS and CDMAM, for which no threshold is defined. CIRS scoring remained close to the reference level down to 40% dose reduction, the inter- and intra-observer variability being the main source of uncertainty. Contrast-detail curves provided by CDMAM overlapped down to 50% dose reduction, at least for object contrast values ranging between 30% and 3%. This multi-phantom study shows the potential of further reducing the dose in full-field digital mammography beyond the current values. A common dose reduction factor around 50% seems acceptable for all phantoms. However, caution is required before extrapolating the results for clinical use, given the limitations of these widely used phantoms, mainly related to their limited dynamic range and uniform background

  8. Hard X-ray full field microscopy and magnifying microtomography using compound refractive lenses

    CERN Document Server

    Schrör, C; Benner, B; Kuhlmann, M; Tümmler, J; Lengeler, B; Rau, C; Weitkamp, T; Snigirev, A; Snigireva, I

    2001-01-01

    For hard X-rays, parabolic compound refractive lenses (PCRLs) are genuine imaging devices like glass lenses for visible light. Based on these new lenses, a hard X-ray full field microscope has been constructed that is ideally suited to image the interior of opaque samples with a minimum of sample preparation. As a result of a large depth of field, CRL micrographs are sharp projection images of most samples. To obtain 3D information about a sample, tomographic techniques are combined with magnified imaging.

  9. Hard X-ray full field microscopy and magnifying microtomography using compound refractive lenses

    Science.gov (United States)

    Schroer, Christian G.; Günzler, Til Florian; Benner, Boris; Kuhlmann, Marion; Tümmler, Johannes; Lengeler, Bruno; Rau, Christoph; Weitkamp, Timm; Snigirev, Anatoly; Snigireva, Irina

    2001-07-01

    For hard X-rays, parabolic compound refractive lenses (PCRLs) are genuine imaging devices like glass lenses for visible light. Based on these new lenses, a hard X-ray full field microscope has been constructed that is ideally suited to image the interior of opaque samples with a minimum of sample preparation. As a result of a large depth of field, CRL micrographs are sharp projection images of most samples. To obtain 3D information about a sample, tomographic techniques are combined with magnified imaging.

  10. Hard X-ray full field microscopy and magnifying microtomography using compound refractive lenses

    International Nuclear Information System (INIS)

    Schroer, Christian G.; Guenzler, Til Florian; Benner, Boris; Kuhlmann, Marion; Tuemmler, Johannes; Lengeler, Bruno; Rau, Christoph; Weitkamp, Timm; Snigirev, Anatoly; Snigireva, Irina

    2001-01-01

    For hard X-rays, parabolic compound refractive lenses (PCRLs) are genuine imaging devices like glass lenses for visible light. Based on these new lenses, a hard X-ray full field microscope has been constructed that is ideally suited to image the interior of opaque samples with a minimum of sample preparation. As a result of a large depth of field, CRL micrographs are sharp projection images of most samples. To obtain 3D information about a sample, tomographic techniques are combined with magnified imaging

  11. Versatility of erbium YAG laser: from fractional skin rejuvenation to full-field skin resurfacing.

    Science.gov (United States)

    Holcomb, J David

    2011-05-01

    For the laser surgeon, the Er-YAG laser is an invaluable tool that delivers unsurpassed ablation efficiency, and with appropriate functionality (quasi long-pulse feature) provides sufficient tissue coagulation to remodel deep rhytids. As such, the 2940-nm wavelength is well suited for routine laser skin rejuvenation in full-field, fractional, and point-beam modes with additional benefits, including applicability to diverse skin types, short healing times, and a low likelihood of energy-related complications. Copyright © 2011 Elsevier Inc. All rights reserved.

  12. Full-field parallel interferometry coherence probe microscope for high-speed optical metrology.

    Science.gov (United States)

    Safrani, A; Abdulhalim, I

    2015-06-01

    Parallel detection of several achromatic phase-shifted images is used to obtain a high-speed, high-resolution, full-field, optical coherence probe tomography system based on polarization interferometry. The high enface imaging speed, short coherence gate, and high lateral resolution provided by the system are exploited to determine microbump height uniformity in an integrated semiconductor chip at 50 frames per second. The technique is demonstrated using the Linnik microscope, although it can be implemented on any polarization-based interference microscopy system.

  13. Full-field optical coherence tomography using immersion Mirau interference microscope.

    Science.gov (United States)

    Lu, Sheng-Hua; Chang, Chia-Jung; Kao, Ching-Fen

    2013-06-20

    In this study, an immersion Mirau interference microscope was developed for full-field optical coherence tomography (FFOCT). Both the reference and measuring arms of the Mirau interferometer were filled with water to prevent the problems associated with imaging a sample in air with conventional FFOCT systems. The almost-common path interferometer makes the tomographic system less sensitive to environmental disturbances. En face OCT images at various depths were obtained with phase-shifting interferometry and Hariharan algorithm. This immersion interferometric method improves depth and quality in three-dimensional OCT imaging of scattering tissue.

  14. Full-field particle velocimetry with a photorefractive optical novelty filter

    International Nuclear Information System (INIS)

    Woerdemann, Mike; Holtmann, Frank; Denz, Cornelia

    2008-01-01

    We utilize the finite time constant of a photorefractive optical novelty filter microscope to access full-field velocity information of fluid flows on microscopic scales. In contrast to conventional methods such as particle image velocimetry and particle tracking velocimetry, not only image acquisition of the tracer particle field but also evaluation of tracer particle velocities is done all-optically by the novelty filter. We investigate the velocity dependent parameters of two-beam coupling based optical novelty filters and demonstrate calibration and application of a photorefractive velocimetry system. Theoretical and practical limits to the range of accessible velocities are discussed

  15. High-Bandwidth Dynamic Full-Field Profilometry for Nano-Scale Characterization of MEMS

    International Nuclear Information System (INIS)

    Chen, L-C; Huang, Y-T; Chang, P-B

    2006-01-01

    The article describes an innovative optical interferometric methodology to delivery dynamic surface profilometry with a measurement bandwidth up to 10MHz or higher and a vertical resolution up to 1 nm. Previous work using stroboscopic microscopic interferometry for dynamic characterization of micro (opto)electromechanical systems (M(O)EMS) has been limited in measurement bandwidth mainly within a couple of MHz. For high resonant mode analysis, the stroboscopic light pulse is insufficiently short to capture the moving fringes from dynamic motion of the detected structure. In view of this need, a microscopic prototype based on white-light stroboscopic interferometry with an innovative light superposition strategy was developed to achieve dynamic full-field profilometry with a high measurement bandwidth up to 10MHz or higher. The system primarily consists of an optical microscope, on which a Mirau interferometric objective embedded with a piezoelectric vertical translator, a high-power LED light module with dual operation modes and light synchronizing electronics unit are integrated. A micro cantilever beam used in AFM was measured to verify the system capability in accurate characterisation of dynamic behaviours of the device. The full-field seventh-mode vibration at a vibratory frequency of 3.7MHz can be fully characterized and nano-scale vertical measurement resolution as well as tens micrometers of vertical measurement range can be performed

  16. Full-field stress determination in photoelasticity with phase shifting technique

    Science.gov (United States)

    Guo, Enhai; Liu, Yonggang; Han, Yongsheng; Arola, Dwayne; Zhang, Dongsheng

    2018-04-01

    Photoelasticity is an effective method for evaluating the stress and its spatial variations within a stressed body. In the present study, a method to determine the stress distribution by means of phase shifting and a modified shear-difference is proposed. First, the orientation of the first principal stress and the retardation between the principal stresses are determined in the full-field through phase shifting. Then, through bicubic interpolation and derivation of a modified shear-difference method, the internal stress is calculated from the point with a free boundary along its normal direction. A method to reduce integration error in the shear difference scheme is proposed and compared to the existing methods; the integration error is reduced when using theoretical photoelastic parameters to calculate the stress component with the same points. Results show that when the value of Δx/Δy approaches one, the error is minimum, and although the interpolation error is inevitable, it has limited influence on the accuracy of the result. Finally, examples are presented for determining the stresses in a circular plate and ring subjected to diametric loading. Results show that the proposed approach provides a complete solution for determining the full-field stresses in photoelastic models.

  17. Full-Field Calibration of Color Camera Chromatic Aberration using Absolute Phase Maps.

    Science.gov (United States)

    Liu, Xiaohong; Huang, Shujun; Zhang, Zonghua; Gao, Feng; Jiang, Xiangqian

    2017-05-06

    The refractive index of a lens varies for different wavelengths of light, and thus the same incident light with different wavelengths has different outgoing light. This characteristic of lenses causes images captured by a color camera to display chromatic aberration (CA), which seriously reduces image quality. Based on an analysis of the distribution of CA, a full-field calibration method based on absolute phase maps is proposed in this paper. Red, green, and blue closed sinusoidal fringe patterns are generated, consecutively displayed on an LCD (liquid crystal display), and captured by a color camera from the front viewpoint. The phase information of each color fringe is obtained using a four-step phase-shifting algorithm and optimum fringe number selection method. CA causes the unwrapped phase of the three channels to differ. These pixel deviations can be computed by comparing the unwrapped phase data of the red, blue, and green channels in polar coordinates. CA calibration is accomplished in Cartesian coordinates. The systematic errors introduced by the LCD are analyzed and corrected. Simulated results show the validity of the proposed method and experimental results demonstrate that the proposed full-field calibration method based on absolute phase maps will be useful for practical software-based CA calibration.

  18. High-Bandwidth Dynamic Full-Field Profilometry for Nano-Scale Characterization of MEMS

    Energy Technology Data Exchange (ETDEWEB)

    Chen, L-C [Graduate Institute of Automation Technology, National Taipei University of Technology, 1 Sec. 3 Chung-Hsiao East Rd., Taipei, 106, Taiwan (China); Huang, Y-T [Graduate Institute of Automation Technology, National Taipei University of Technology, 1 Sec. 3 Chung-Hsiao East Rd., Taipei, 106, Taiwan (China); Chang, P-B [Graduate Institute of Mechanical and Electrical Engineering, National Taipei University of Technology, 1 Sec. 3 Chung-Hsiao East Rd., Taipei, 106, Taiwan (China)

    2006-10-15

    The article describes an innovative optical interferometric methodology to delivery dynamic surface profilometry with a measurement bandwidth up to 10MHz or higher and a vertical resolution up to 1 nm. Previous work using stroboscopic microscopic interferometry for dynamic characterization of micro (opto)electromechanical systems (M(O)EMS) has been limited in measurement bandwidth mainly within a couple of MHz. For high resonant mode analysis, the stroboscopic light pulse is insufficiently short to capture the moving fringes from dynamic motion of the detected structure. In view of this need, a microscopic prototype based on white-light stroboscopic interferometry with an innovative light superposition strategy was developed to achieve dynamic full-field profilometry with a high measurement bandwidth up to 10MHz or higher. The system primarily consists of an optical microscope, on which a Mirau interferometric objective embedded with a piezoelectric vertical translator, a high-power LED light module with dual operation modes and light synchronizing electronics unit are integrated. A micro cantilever beam used in AFM was measured to verify the system capability in accurate characterisation of dynamic behaviours of the device. The full-field seventh-mode vibration at a vibratory frequency of 3.7MHz can be fully characterized and nano-scale vertical measurement resolution as well as tens micrometers of vertical measurement range can be performed.

  19. Full-field x-ray nano-imaging at SSRF

    Science.gov (United States)

    Deng, Biao; Ren, Yuqi; Wang, Yudan; Du, Guohao; Xie, Honglan; Xiao, Tiqiao

    2013-09-01

    Full field X-ray nano-imaging focusing on material science is under developing at SSRF. A dedicated full field X-ray nano-imaging beamline based on bending magnet will be built in the SSRF phase-II project. The beamline aims at the 3D imaging of the nano-scale inner structures. The photon energy range is of 5-14keV. The design goals with the field of view (FOV) of 20μm and a spatial resolution of 20nm are proposed at 8 keV, taking a Fresnel zone plate (FZP) with outermost zone width of 25 nm. Futhermore, an X-ray nano-imaging microscope is under developing at the SSRF BL13W beamline, in which a larger FOV will be emphasized. This microscope is based on a beam shaper and a zone plate using both absorption contrast and Zernike phase contrast, with the optimized energy set to 10keV. The detailed design and the progress of the project will be introduced.

  20. Full-field dye concentration measurement within saturated/unsaturated thin slabs of porous media

    International Nuclear Information System (INIS)

    Norton, D.L.; Glass, R.J.

    1993-01-01

    This paper presents a full-field dye concentration measurement technique that extends our experimental capabilities to the measurement of transient dye concentration fields within steady state flow fields under unsaturated or saturated conditions. Simple light absorption theory provides a basis for translating images into high resolution dye concentration fields. A series of dye pulse experiments that demonstrate the combined use of the full-field saturation and dye concentration techniques was conducted at four different degrees of saturation. Each of these experimental sequences was evaluated with respect to mass balance, the results being within 5% of the known dye mass input. An image windowing technique allowed us to see increased dispersion due to decreasing moisture content, tailing of concentration at the rear of the dye pulse and slight velocity changes of the dispersive front due to changes in moisture content. The exceptional resolution of dye concentration in space and time provided by this laboratory technique allows systematic experimentation for examining basic processes affecting solute transport within saturated/unsaturated porous media. Future challenges for this work will be to use these techniques to analyze more complex systems involving heterogeneities, scaling laws, and detailed investigations of the relationship between transverse and longitudinal dispersion in unsaturated media

  1. Usefulness of DICOM headers in the analysis of two biplane X-ray systems setting (image intensifier and flat panel) used in pediatric interventional cardiology in Chile;Utilidad de las cabeceras DICOM en el analisis de la configuracion de dos sistemas de rayos X biplano (intensificador de imagen y panel plano) utilizados en cardiologia intervencionista pediatrica en Chile

    Energy Technology Data Exchange (ETDEWEB)

    Ubeda, C.; Vergara, F. [Universidad de Tarapaca, Arica (Chile). Dept. de Ciencias Clinicas; Vano, E. [Universidad Complutense, Madrid, (Spain). Hospital Clinico San Carlos. Dept. de Radiologia; Miranda, P. [Hospital Luis Calvo Mackenna, Santiago (Chile). Dept. de Hemodinamia; Valenzuela, E. [Universidad Catolica de Chile, Santiago (Chile). Hospital Clinico. Servicio de Hemodinamia; Leyton, F. [Instituto de Salud Publica de Chile, Santiago (Chile)

    2009-07-01

    The setting of two biplane X ray systems were evaluated (image intensifier (II) and flat panel (PP)), through DICOM tags from 32 images created during the characterization of both systems. The technical parameters adjusted for systems were: 63,8 to 80,0 kV and 15,0 to 388,0 mA, for the system with II and 52,0 to 77,0 kV and 25,0 to 476,0 mA, for the system with PP detector. Both equipment presented a different mA adjustment, when moving from fluoroscopy modes low dose (FL), medium dose (FM) and high dose (FH) to cine mode (CI). Two dosimetric quantities were evaluated, the first one was the dose-area product (DAP) which gave as a result for FB mode, between 0,03 to 0,35 uGycm{sup 2}/image (II) and from 0,05 a 0,69 uGycm{sup 2}/image (PP), when the polymethyl methacrylate (PMMA) thickness was incremented from 4 to 16 cm. In cine mode the DAP quantity showed, percentage values from 24 to -1 % for the same PMMA increment. Skin cumulative dose was the second quantity evaluated and showed an increment of incident air kerma (KAI)/image in factors from 17 to 35 (II) and 15 to 28 (PP) when used in CI mode instead of FB mode, to the different PMMA thicknesses used. This dose increment for CI mode must be considered by cardiologists, to use the fluoroscopic run as an alternative to document part of the procedures when there is no need to use a high quality image (author)

  2. Effective x-ray attenuation measurements with full field digital mammography

    International Nuclear Information System (INIS)

    Heine, John J.; Behera, Madhusmita

    2006-01-01

    This work shows that effective x-ray attenuation coefficients may be estimated by applying Beer's Law to phantom image data acquired with the General Electric Senographe 2000D full field digital mammography system. Theoretical developments are provided indicating that an approximate form of the Beer's relation holds for polychromatic x-ray beams. The theoretical values were compared with experimentally determined measured values, which were estimated at various detector locations. The measured effective attenuation coefficients are in agreement with those estimated with theoretical developments and numerical integration. The work shows that the measured quantities show little spatial variation. The main ideas are demonstrated with polymethylmethacrylate and breast tissue equivalent phantom imaging experiments. The work suggests that the effective attenuation coefficients may be used as known values for radiometric standardization applications that compensate for the image acquisition influences. The work indicates that it is possible to make quantitative attenuation coefficient measurements from a system designed for clinical purposes

  3. Full-Field Optical Coherence Tomography as a Diagnosis Tool: Recent Progress with Multimodal Imaging

    Directory of Open Access Journals (Sweden)

    Olivier Thouvenin

    2017-03-01

    Full Text Available Full-field optical coherence tomography (FF-OCT is a variant of OCT that is able to register 2D en face views of scattering samples at a given depth. Thanks to its superior resolution, it can quickly reveal information similar to histology without the need to physically section the sample. Sensitivity and specificity levels of diagnosis performed with FF-OCT are 80% to 95% of the equivalent histological diagnosis performances and could therefore benefit from improvement. Therefore, multimodal systems have been designed to increase the diagnostic performance of FF-OCT. In this paper, we will discuss which contrasts can be measured with such multimodal systems in the context of ex vivo biological tissue examination. We will particularly emphasize three multimodal combinations to measure the tissue mechanics, dynamics, and molecular content respectively.

  4. Evaluation of mean glandular dose in a full-field digital mammography unit in Tabriz (IR)

    International Nuclear Information System (INIS)

    Riabi, H. A.; Mehnati, P.; Mesbahi, A.

    2010-01-01

    This study was aimed at evaluating the mean glandular dose (MGD) and affecting factors during mammography examinations by a full-field digital mammography unit. An extensive quality control program was performed to assure that the unit is properly working. Required information including compressed breast thickness (CBT), breast parenchymal pattern and technical factors used for imaging were recorded. An entrance skin exposure measurement was also performed using slabs of polymethylmethacrylate with 2-8 cm thickness. On the basis of recorded information and measured data, the MGD was estimated for 1145 mammography examinations obtained from 298 patients. Mean CBTs of 4.9 and 5.8 cm and MGDs of 2 and 2.4 mGy were observed for cranio-caudal and medio-lateral oblique views, respectively. Significant correlation was seen between MGD and CBT, breast parenchymal pattern and applied kVp and mAs. (authors)

  5. A domain decomposition approach for full-field measurements based identification of local elastic parameters

    KAUST Repository

    Lubineau, Gilles

    2015-03-01

    We propose a domain decomposition formalism specifically designed for the identification of local elastic parameters based on full-field measurements. This technique is made possible by a multi-scale implementation of the constitutive compatibility method. Contrary to classical approaches, the constitutive compatibility method resolves first some eigenmodes of the stress field over the structure rather than directly trying to recover the material properties. A two steps micro/macro reconstruction of the stress field is performed: a Dirichlet identification problem is solved first over every subdomain, the macroscopic equilibrium is then ensured between the subdomains in a second step. We apply the method to large linear elastic 2D identification problems to efficiently produce estimates of the material properties at a much lower computational cost than classical approaches.

  6. Comparison of two approaches for differentiating full-field data in solid mechanics

    International Nuclear Information System (INIS)

    Avril, Stéphane; Feissel, Pierre; Villon, Pierre; Pierron, Fabrice

    2010-01-01

    In this study, the issue of reconstructing the gradients of noisy full-field data is addressed within the framework of solid mechanics. Two approaches are considered, a global one based on finite element approximation (FEA) and a local one based on diffuse approximation (DA). For both approaches, it is proposed to monitor locally the filtering effect in order to adapt the uncertainty to the local signal to noise ratio. Both approaches are applied to a case study which is commonly considered as difficult in solid mechanics (open-hole tensile test on a composite laminate). Both DA and FEA are successful for detecting local subsurface damage from the measured noisy displacement fields. Indications are also provided about the compared performances of DA and FEA. It is shown that DA is more robust, but the downside is that it is also more CPU time consuming

  7. Use of Iodine-based contrast media in digital full-field mammography - initial experience

    International Nuclear Information System (INIS)

    Diekmann, F.; Diekmann, S.; Taupitz, M.; Bick, U.; Winzer, K.-J.; Huettner, C.; Muller, S.; Jeunehomme, F.; Hamm, B.

    2003-01-01

    Aim: To investigate the use of iodine-based contrast media in digital full-field mammography. Methods: After performing initial phantom studies, seven patients underwent digital mammography (Senographe 2000D, GE Medical Systems, Milwaukee, USA) using a specially filtered beam before as well as 60, 120, and 180 seconds after injection of 80 ml of iodine contrast medium (Ultravist 370, Schering AG, Germany). The precontrast mammograms were then subtracted from the postcontrast mammograms and the resulting images compared with a contrast-enhanced dynamic MRI study, performed on all women. Results: Contrast medium accumulation within the tumors was visualized with a good quality in all cases. The conditions under which successful contrast-enhanced digital mammography can be performed were determined in phantom studies. Conclusions: Contrast-enhanced digital mammography has a potential for improving the visualization of breast tumors in mammography using special beam filtering, adjusted X-ray parameters, proper timing, and suitable subtraction software. (orig.) [de

  8. Full-field implementation of a perfect eavesdropper on a quantum cryptography system.

    Science.gov (United States)

    Gerhardt, Ilja; Liu, Qin; Lamas-Linares, Antía; Skaar, Johannes; Kurtsiefer, Christian; Makarov, Vadim

    2011-06-14

    Quantum key distribution (QKD) allows two remote parties to grow a shared secret key. Its security is founded on the principles of quantum mechanics, but in reality it significantly relies on the physical implementation. Technological imperfections of QKD systems have been previously explored, but no attack on an established QKD connection has been realized so far. Here we show the first full-field implementation of a complete attack on a running QKD connection. An installed eavesdropper obtains the entire 'secret' key, while none of the parameters monitored by the legitimate parties indicate a security breach. This confirms that non-idealities in physical implementations of QKD can be fully practically exploitable, and must be given increased scrutiny if quantum cryptography is to become highly secure.

  9. Development of hard X-ray dark-field microscope using full-field optics

    International Nuclear Information System (INIS)

    Takano, Hidekazu; Azuma, Hiroaki; Shimomura, Sho; Tsuji, Takuya; Tsusaka, Yoshiyuki; Kagoshima, Yasushi

    2016-01-01

    We develop a dark-field X-ray microscope using full-field optics based on a synchrotron beamline. Our setup consists of a condenser system and a microscope objective with an angular acceptance larger than that of the condenser. The condenser system is moved downstream from its regular position such that the focus of the condenser is behind the objective. The dark-field microscope optics are configured by excluding the converging beam from the condenser at the focal point. The image properties of the system are evaluated by observing and calculating a Siemens star test chart with 10 keV X-rays. Our setup allows easy switching to bright-field imaging. (author)

  10. Broad frequency band full field measurements for advanced applications: Point-wise comparisons between optical technologies

    Science.gov (United States)

    Zanarini, Alessandro

    2018-01-01

    The progress of optical systems gives nowadays at disposal on lightweight structures complex dynamic measurements and modal tests, each with its own advantages, drawbacks and preferred usage domains. It is thus more easy than before to obtain highly spatially defined vibration patterns for many applications in vibration engineering, testing and general product development. The potential of three completely different technologies is here benchmarked on a common test rig and advanced applications. SLDV, dynamic ESPI and hi-speed DIC are here first deployed in a complex and unique test on the estimation of FRFs with high spatial accuracy from a thin vibrating plate. The latter exhibits a broad band dynamics and high modal density in the common frequency domain where the techniques can find an operative intersection. A peculiar point-wise comparison is here addressed by means of discrete geometry transforms to put all the three technologies on trial at each physical point of the surface. Full field measurement technologies cannot estimate only displacement fields on a refined grid, but can exploit the spatial consistency of the results through neighbouring locations by means of numerical differentiation operators in the spatial domain to obtain rotational degrees of freedom and superficial dynamic strain distributions, with enhanced quality, compared to other technologies in literature. Approaching the task with the aid of superior quality receptance maps from the three different full field gears, this work calculates and compares rotational and dynamic strain FRFs. Dynamic stress FRFs can be modelled directly from the latter, by means of a constitutive model, avoiding the costly and time-consuming steps of building and tuning a numerical dynamic model of a flexible component or a structure in real life conditions. Once dynamic stress FRFs are obtained, spectral fatigue approaches can try to predict the life of a component in many excitation conditions. Different

  11. Applications of Hard X-ray Full-Field Transmission X-ray Microscopy at SSRL

    International Nuclear Information System (INIS)

    Liu, Y.; Andrews, J. C.; Mehta, A.; Pianetta, P.; Meirer, F.; Gil, S. Carrasco; Sciau, P.; Mester, Z.

    2011-01-01

    State-of-the-art hard x-ray full-field transmission x-ray microscopy (TXM) at beamline 6-2C of Stanford Synchrotron Radiation Lightsource has been applied to various research fields including biological, environmental, and material studies. With the capability of imaging a 32-micron field-of-view at 30-nm resolution using both absorption mode and Zernike phase contrast, the 3D morphology of yeast cells grown in gold-rich media was investigated. Quantitative evaluation of the absorption coefficient was performed for mercury nanoparticles in alfalfa roots exposed to mercury. Combining XANES and TXM, we also performed XANES-imaging on an ancient pottery sample from the Roman pottery workshop at LaGraufesenque (Aveyron).

  12. Applications of Hard X-ray Full-Field Transmission X-ray Microscopy at SSRL

    Science.gov (United States)

    Liu, Y.; Andrews, J. C.; Meirer, F.; Mehta, A.; Gil, S. Carrasco; Sciau, P.; Mester, Z.; Pianetta, P.

    2011-09-01

    State-of-the-art hard x-ray full-field transmission x-ray microscopy (TXM) at beamline 6-2C of Stanford Synchrotron Radiation Lightsource has been applied to various research fields including biological, environmental, and material studies. With the capability of imaging a 32-micron field-of-view at 30-nm resolution using both absorption mode and Zernike phase contrast, the 3D morphology of yeast cells grown in gold-rich media was investigated. Quantitative evaluation of the absorption coefficient was performed for mercury nanoparticles in alfalfa roots exposed to mercury. Combining XANES and TXM, we also performed XANES-imaging on an ancient pottery sample from the Roman pottery workshop at LaGraufesenque (Aveyron).

  13. Qualitative investigation of fresh human scalp hair with full-field optical coherence tomography

    Science.gov (United States)

    Choi, Woo June; Pi, Long-Quan; Min, Gihyeon; Lee, Won-Soo; Lee, Byeong Ha

    2012-03-01

    We have investigated depth-resolved cellular structures of unmodified fresh human scalp hairs with ultrahigh-resolution full-field optical coherence tomography (FF-OCT). The Linnik-type white light interference microscope has been home-implemented to observe the micro-internal layers of human hairs in their natural environment. In hair shafts, FF-OCT has qualitatively revealed the cellular hair compartments of cuticle and cortex layers involved in keratin filaments and melanin granules. No significant difference between black and white hair shafts was observed except for absence of only the melanin granules in the white hair, reflecting that the density of the melanin granules directly affects the hair color. Anatomical description of plucked hair bulbs was also obtained with the FF-OCT in three-dimensions. We expect this approach will be useful for evaluating cellular alteration of natural hairs on cosmetic assessment or diagnosis of hair diseases.

  14. Dual-energy imaging in full-field digital mammography: a phantom study

    International Nuclear Information System (INIS)

    Taibi, A; Fabbri, S; Baldelli, P; Maggio, C di; Gennaro, G; Marziani, M; Tuffanelli, A; Gambaccini, M

    2003-01-01

    A dual-energy technique which employs the basis decomposition method is being investigated for application to digital mammography. A three-component phantom, made up of plexiglas, polyethylene and water, was doubly exposed with the full-field digital mammography system manufactured by General Electric. The 'low' and 'high' energy images were recorded with a Mo/Mo anode-filter combination and a Rh/Rh combination, respectively. The total dose was kept within the acceptable levels of conventional mammography. The first hybrid images obtained with the dual-energy algorithm are presented in comparison with a conventional radiograph of the phantom. Image-quality characteristics at contrast cancellation angles between plexiglas and water are discussed. Preliminary results show that a combination of a standard Mo-anode 28 kV radiograph with a Rh-anode 49 kV radiograph provides the best compromise between image-quality and dose in the hybrid image

  15. In vivo high resolution human corneal imaging using full-field optical coherence tomography.

    Science.gov (United States)

    Mazlin, Viacheslav; Xiao, Peng; Dalimier, Eugénie; Grieve, Kate; Irsch, Kristina; Sahel, José-Alain; Fink, Mathias; Boccara, A Claude

    2018-02-01

    We present the first full-field optical coherence tomography (FFOCT) device capable of in vivo imaging of the human cornea. We obtained images of the epithelial structures, Bowman's layer, sub-basal nerve plexus (SNP), anterior and posterior stromal keratocytes, stromal nerves, Descemet's membrane and endothelial cells with visible nuclei. Images were acquired with a high lateral resolution of 1.7 µm and relatively large field-of-view of 1.26 mm x 1.26 mm - a combination, which, to the best of our knowledge, has not been possible with other in vivo human eye imaging methods. The latter together with a contactless operation, make FFOCT a promising candidate for becoming a new tool in ophthalmic diagnostics.

  16. Study of Wood Plastic Composites elastic behaviour using full field measurements

    Directory of Open Access Journals (Sweden)

    Graciaa A.

    2010-06-01

    Full Text Available In this study, the mechanical properties and microstructure of HDPE/wood fibre composites are investigated. The four-point bending and tensile behaviour of Wood Plastic Composite (WPC with or without additive are studied by using full-field strain measurements by 3-D Digital Image Correlation (3-D DIC. A non-linear behaviour is shown. The modulus of elasticity (MOE is calculated as the tangent at zero strain of a Maxwell-Bingham model fitted onto experimental data. Four-point bending tests are analyzed thanks to the spatial standard deviation of the longitudinal strain field to determine the degree of heterogeneity. Cyclic tensile tests have been performed in order to analyze the damage of the material. Moreover, Scanning Electron Microscope (SEM is used to characterize the morphology of the wood fibre/HDPE matrix interface for specimens with maleic anhydride modified polyethylene additive (MAPE.

  17. Study of Wood Plastic Composites elastic behaviour using full field measurements

    Science.gov (United States)

    Ben Mbarek, T.; Robert, L.; Hugot, F.; Orteu, J. J.; Sammouda, H.; Graciaa, A.; Charrier, B.

    2010-06-01

    In this study, the mechanical properties and microstructure of HDPE/wood fibre composites are investigated. The four-point bending and tensile behaviour of Wood Plastic Composite (WPC) with or without additive are studied by using full-field strain measurements by 3-D Digital Image Correlation (3-D DIC). A non-linear behaviour is shown. The modulus of elasticity (MOE) is calculated as the tangent at zero strain of a Maxwell-Bingham model fitted onto experimental data. Four-point bending tests are analyzed thanks to the spatial standard deviation of the longitudinal strain field to determine the degree of heterogeneity. Cyclic tensile tests have been performed in order to analyze the damage of the material. Moreover, Scanning Electron Microscope (SEM) is used to characterize the morphology of the wood fibre/HDPE matrix interface for specimens with maleic anhydride modified polyethylene additive (MAPE).

  18. Tissue imaging using full field optical coherence microscopy with short multimode fiber probe

    Science.gov (United States)

    Sato, Manabu; Eto, Kai; Goto, Tetsuhiro; Kurotani, Reiko; Abe, Hiroyuki; Nishidate, Izumi

    2018-03-01

    In achieving minimally invasive accessibility to deeply located regions the size of the imaging probes is important. We demonstrated full-field optical coherence tomography (FF-OCM) using an ultrathin forward-imaging short multimode fiber (SMMF) probe of 50 μm core diameter, 125 μm diameter, and 7.4 mm length for optical communications. The axial resolution was measured to be 2.14 μm and the lateral resolution was also evaluated to be below 4.38 μm using a test pattern (TP). The spatial mode and polarization characteristics of SMMF were evaluated. Inserting SMMF to in vivo rat brain, 3D images were measured and 2D information of nerve fibers was obtained. The feasibility of an SMMF as an ultrathin forward-imaging probe in FF-OCM has been demonstrated.

  19. Dose reduction through gridless technique in digital full-field mammography

    International Nuclear Information System (INIS)

    Diekmann, F.; Diekmann, S.; Berzeg, S.; Blick, U.; Fischer, T.; Hamm, B.

    2003-01-01

    Purpose: To determine the role of the scatter grid in digital full-field mammography with respect to image quality and dose and to compare the experimental results with initial clinical experience. Materials and Methods: A phantom consisting of 205 fields that enclose gold dots of different thickness and size (CD-Mam phantom, Medical Department, Nijmegen, Netherlands) was used for digital full-field mammography with the conventional grid module and a special gridless module. Four different breast thicknesses were simulated using Plexiglas as scatter material. First, the phantom was exposed at the parameter and dose settings automatically selected in each experimental setup (with and without grid). Subsequently, the phantom was exposed at the different simulated breast thicknesses using the gridless module in combination with the parameters automatically selected for the grid module. This was followed by a series of phantom mammograms obtained with the experimental setup reversed. The 16 mammograms were evaluated by 3 readers and the results compared considering breast thickness, radiation dose, and quality. The gridless module was used for preoperative labeling in 16 patients for comparison of mammograms obtained with and without a grid. Results: For the same entrance dose used in routine mammography, digital mammography without grid is superior to digital mammography with grid when performed on simulated thin breasts (Plexiglas less than 3 cm), with no difference found when performed on simulated large breasts. The advantages of gridless mammography are more pronounced at a markedly reduced entrance dose (identical parenchymal dose without and with grid using the dose automatically selected for the gridless module). This tendency is confirmed by the initial clinical comparison. (orig.) [de

  20. Transportable and vibration-free full-field low-coherent quantitative phase microscope

    Science.gov (United States)

    Yamauchi, Toyohiko; Yamada, Hidenao; Goto, Kentaro; Matsui, Hisayuki; Yasuhiko, Osamu; Ueda, Yukio

    2018-02-01

    We developed a transportable Linnik-type full-field low-coherent quantitative phase microscope that is able to compensate for optical path length (OPL) disturbance due to environmental mechanical noises. Though two-beam interferometers such as Linnik ones suffer from unstable OPL difference, we overcame this problem with a mechanical feedback system based on digital signal-processing that controls the OPL difference in sub-nanometer resolution precisely with a feedback bandwidth of 4 kHz. The developed setup has a footprint of 200 mm by 200 mm, a height of 500 mm, and a weight of 4.5 kilograms. In the transmission imaging mode, cells were cultured on a reflection-enhanced glass-bottom dish, and we obtained interference images sequentially while performing stepwise quarter-wavelength phase-shifting. Real-time image processing, including retrieval of the unwrapped phase from interference images and its background correction, along with the acquisition of interference images, was performed on a laptop computer. Emulation of the phase contrast (PhC) images and the differential interference contrast (DIC) images was also performed in real time. Moreover, our setup was applied for full-field cell membrane imaging in the reflection mode, where the cells were cultured on an anti-reflection (AR)-coated glass-bottom dish. The phase and intensity of the light reflected by the membrane revealed the outer shape of the cells independent of the refractive index. In this paper, we show imaging results on cultured cells in both transmission and reflection modes.

  1. Reframing measurement for structural health monitoring: a full-field strategy for structural identification

    Science.gov (United States)

    Dizaji, Mehrdad S.; Harris, Devin K.; Alipour, Mohamad; Ozbulut, Osman E.

    2018-03-01

    Structural health monitoring (SHM) describes a decision-making framework that is fundamentally guided by state change detection of structural systems. This framework typically relies on the use of continuous or semi-continuous monitoring of measured response to quantify this state change in structural system behavior, which is often related to the initiation of some form of damage. Measurement approaches used for traditional SHM are numerous, but most are limited to either describing localized or global phenomena, making it challenging to characterize operational structural systems which exhibit both. In addition to these limitations in sensing, SHM has also suffered from the inherent robustness inherent to most full-scale structural systems, making it challenging to identify local damage. These challenges highlight the opportunity for alternative strategies for SHM, strategies that are able to provide data suitable to translate into rich information. This paper describes preliminary results from a refined structural identification (St-ID) approach using fullfield measurements derived from high-speed 3D Digital Image Correlation (HSDIC) to characterize uncertain parameters (i.e. boundary and constitutive properties) of a laboratory scale structural component. The St-ID approach builds from prior work by supplementing full-field deflection and strain response with vibration response derived from HSDIC. Inclusion of the modal characteristics within a hybrid-genetic algorithm optimization scheme allowed for simultaneous integration of mechanical and modal response, thus enabling a more robust St-ID strategy than could be achieved with traditional sensing techniques. The use of full-field data is shown to provide a more comprehensive representation of the global and local behavior, which in turn increases the robustness of the St-Id framework. This work serves as the foundation for a new paradigm in SHM that emphasizes characterizing structural performance using a

  2. Applying a Bayesian Approach to Identification of Orthotropic Elastic Constants from Full Field Displacement Measurements

    Directory of Open Access Journals (Sweden)

    Le Riche R.

    2010-06-01

    Full Text Available A major challenge in the identification of material properties is handling different sources of uncertainty in the experiment and the modelling of the experiment for estimating the resulting uncertainty in the identified properties. Numerous improvements in identification methods have provided increasingly accurate estimates of various material properties. However, characterizing the uncertainty in the identified properties is still relatively crude. Different material properties obtained from a single test are not obtained with the same confidence. Typically the highest uncertainty is associated with respect to properties to which the experiment is the most insensitive. In addition, the uncertainty in different properties can be strongly correlated, so that obtaining only variance estimates may be misleading. A possible approach for handling the different sources of uncertainty and estimating the uncertainty in the identified properties is the Bayesian method. This method was introduced in the late 1970s in the context of identification [1] and has been applied since to different problems, notably identification of elastic constants from plate vibration experiments [2]-[4]. The applications of the method to these classical pointwise tests involved only a small number of measurements (typically ten natural frequencies in the previously cited vibration test which facilitated the application of the Bayesian approach. For identifying elastic constants, full field strain or displacement measurements provide a high number of measured quantities (one measurement per image pixel and hence a promise of smaller uncertainties in the properties. However, the high number of measurements represents also a major computational challenge in applying the Bayesian approach to full field measurements. To address this challenge we propose an approach based on the proper orthogonal decomposition (POD of the full fields in order to drastically reduce their

  3. Applying a Bayesian Approach to Identification of Orthotropic Elastic Constants from Full Field Displacement Measurements

    Science.gov (United States)

    Gogu, C.; Yin, W.; Haftka, R.; Ifju, P.; Molimard, J.; Le Riche, R.; Vautrin, A.

    2010-06-01

    A major challenge in the identification of material properties is handling different sources of uncertainty in the experiment and the modelling of the experiment for estimating the resulting uncertainty in the identified properties. Numerous improvements in identification methods have provided increasingly accurate estimates of various material properties. However, characterizing the uncertainty in the identified properties is still relatively crude. Different material properties obtained from a single test are not obtained with the same confidence. Typically the highest uncertainty is associated with respect to properties to which the experiment is the most insensitive. In addition, the uncertainty in different properties can be strongly correlated, so that obtaining only variance estimates may be misleading. A possible approach for handling the different sources of uncertainty and estimating the uncertainty in the identified properties is the Bayesian method. This method was introduced in the late 1970s in the context of identification [1] and has been applied since to different problems, notably identification of elastic constants from plate vibration experiments [2]-[4]. The applications of the method to these classical pointwise tests involved only a small number of measurements (typically ten natural frequencies in the previously cited vibration test) which facilitated the application of the Bayesian approach. For identifying elastic constants, full field strain or displacement measurements provide a high number of measured quantities (one measurement per image pixel) and hence a promise of smaller uncertainties in the properties. However, the high number of measurements represents also a major computational challenge in applying the Bayesian approach to full field measurements. To address this challenge we propose an approach based on the proper orthogonal decomposition (POD) of the full fields in order to drastically reduce their dimensionality. POD is

  4. Owhership of flats

    OpenAIRE

    Přibil, Jan

    2012-01-01

    Ownership of Flats Summary In his diploma thesis "Ownership of Flats", the author focuses on applicable law of flat ownership in the Czech Republic, especially the Flat Ownership Act 72/1994 Sb. The author puts the contemporary regulation in historical context; he describes the theoretical principles underlining the current applicable law and defines in detail the basic legal terms used by the Flat Ownership Act. Original and derivative forms of flat ownership acquisition are explained, namel...

  5. Homogenization of linear viscoelastic three phase media: internal variable formulation versus full-field computation

    International Nuclear Information System (INIS)

    Blanc, V.; Barbie, L.; Masson, R.

    2011-01-01

    Homogenization of linear viscoelastic heterogeneous media is here extended from two phase inclusion-matrix media to three phase inclusion-matrix media. Each phase obeying to a compressible Maxwellian behaviour, this analytic method leads to an equivalent elastic homogenization problem in the Laplace-Carson space. For some particular microstructures, such as the Hashin composite sphere assemblage, an exact solution is obtained. The inversion of the Laplace-Carson transforms of the overall stress-strain behaviour gives in such cases an internal variable formulation. As expected, the number of these internal variables and their evolution laws are modified to take into account the third phase. Moreover, evolution laws of averaged stresses and strains per phase can still be derived for three phase media. Results of this model are compared to full fields computations of representative volume elements using finite element method, for various concentrations and sizes of inclusion. Relaxation and creep test cases are performed in order to compare predictions of the effective response. The internal variable formulation is shown to yield accurate prediction in both cases. (authors)

  6. A new full-field interferometry approach for counting and differentiating aquatic biotic nanoparticles (Conference Presentation)

    Science.gov (United States)

    Boccara, A. Claude; Fedala, Yasmina; Voronkoff, Justine; Paffoni, Nina; Boccara, Martine

    2017-03-01

    Due to the huge abundance and the major role that viruses and membrane vesicles play in the seas or rivers ecosystems it is necessary to develop simple, sensitive, compact and reliable methods for their detection and characterization. Our approach is based on the measurement of the weak light level scattered by the biotic nanoparticles. We describe a new full-field, incoherently illuminated, shot-noise limited, common-path interferometric detection method coupled with the analysis of Brownian motion to detect, quantify, and differentiate biotic nanoparticles. The last developments take advantage of a new fast (700 Hz) camera with 2 Me- full well capacity that improves the signal to noise ratio and increases the precision of the Brownian motion characterization. We validated the method with calibrated nanoparticles and homogeneous DNA or RNA.viruses. The smallest virus size that we characterized with a suitable signal-to-noise ratio was around 30 nm in diameter with a target towards the numerous 20 nm diameter viruses. We show for the first time anisotropic trajectories for myoviruses meaning that there is a memory of the initial direction of their Brownian motions. Significant improvements have been made in the handling of the sample as well as in the statistical analysis for differentiating the various families of vesicles and virus. We further applied the method for vesicles detection and for analysis of coastal and oligotrophic samples from Tara Oceans circumnavigation as well of various rivers.

  7. Full-Field Strain Mapping at a Ge/Si Heterostructure Interface

    Directory of Open Access Journals (Sweden)

    Buwen Cheng

    2013-05-01

    Full Text Available The misfit dislocations and strain fields at a Ge/Si heterostructure interface were investigated experimentally using a combination of high-resolution transmission electron microscopy and quantitative electron micrograph analysis methods. The type of misfit dislocation at the interface was determined to be 60° dislocation and 90° full-edge dislocation. The full-field strains at the Ge/Si heterostructure interface were mapped by using the geometric phase analysis (GPA and peak pairs analysis (PPA, respectively. The effect of the mask size on the GPA and PPA results was analyzed in detail. For comparison, the theoretical strain fields of the misfit dislocations were also calculated by the Peierls-Nabarro and Foreman dislocation models. The results showed that the optimal mask sizes in GPA and PPA were approximately three tenths and one-tenth of the reciprocal lattice vector, respectively. The Foreman dislocation model with an alterable factor a = 4 can best describe the strain field of the misfit dislocation at the Ge/Si heterostructure interface.

  8. Radiation exposure of contrast-enhanced spectral mammography compared with full-field digital mammography.

    Science.gov (United States)

    Jeukens, Cécile R L P N; Lalji, Ulrich C; Meijer, Eduard; Bakija, Betina; Theunissen, Robin; Wildberger, Joachim E; Lobbes, Marc B I

    2014-10-01

    Contrast-enhanced spectral mammography (CESM) shows promising initial results but comes at the cost of increased dose as compared with full-field digital mammography (FFDM). We aimed to quantitatively assess the dose increase of CESM in comparison with FFDM. Radiation exposure-related data (such as kilovoltage, compressed breast thickness, glandularity, entrance skin air kerma (ESAK), and average glandular dose (AGD) were retrieved for 47 CESM and 715 FFDM patients. All examinations were performed on 1 mammography unit. Radiation dose values reported by the unit were validated by phantom measurements. Descriptive statistics of the patient data were generated using a statistical software package. Dose values reported by the mammography unit were in good qualitative agreement with those of phantom measurements. Mean ESAK was 10.5 mGy for a CESM exposure and 7.46 mGy for an FFDM exposure. Mean AGD for a CESM exposure was 2.80 mGy and 1.55 mGy for an FFDM exposure. Compared with our institutional FFDM, the AGD of a single CESM exposure is increased by 1.25 mGy (+81%), whereas ESAK is increased by 3.07 mGy (+41%). Dose values of both techniques meet the recommendations for maximum dose in mammography.

  9. Breast Glandularity in Malaysian Women from a Full-Field Digital Mammography System

    International Nuclear Information System (INIS)

    Noriah Jamal; Humairah Samad Cheung; Siti Selina Abdul Hamid; Juliana Mahamad Napiah

    2014-01-01

    This study is undertaken to estimate breast glandularity in Malaysian women from a Full-Field Digital mammography System. This study involved 223 women (Malay=100;Chinese=101 and Indian=22) underwent voluntary screening mammography at Breast Centre, International Islamic University Malaysia (IIUM Breast Centre) for the first quarter of year 2009. Those are women aged between 31 to 69 years old (median age, 49 years). Data on miliampere-seconds, kilo voltage and compressed breast thickness for each cranio caudal view are used to estimate breast glandularity for an individual breast. Breast glandularity is calculated using the fitted equation reported earlier. The difference in breast glandularity among ethnic groups was tested for significance using the nonparametric Kruskal-Wallis test. The average breast glandularity estimated in our study, using FFDM system is 52.94±27.63 %. No significant difference was seen in breast glandularity among the ethnic groups (p>0.05, Kruskan Wallis test). Breast glandularity decrease as age increases, up to 60 years old. (author)

  10. Characterization of microcalcification: can digital monitor zooming replace magnification mammography in full-field digital mammography?

    International Nuclear Information System (INIS)

    Kim, Min Jung; Kim, Eun-Kyung; Kwak, Jin Young; Son, Eun Ju; Youk, Ji Hyun; Choi, Seon Hyeong; Oh, Ki Keun; Han, Mooyoung

    2009-01-01

    The aim of this study was to compare the diagnostic accuracy and image quality of microcalcifications in zoomed digital contact mammography with digital magnification mammography. Three radiologists with different levels of experience in mammography reviewed 120 microcalcification clusters in 111 patients with a full-field digital mammography system relying on digital magnification mammogram (MAG) images and zoomed images from contact mammography (ZOOM) using commercially available zooming systems on monitors. Each radiologist estimated the probability of malignancy and rated the image quality and confidence rate. Performance was evaluated by sensitivity, specificity, positive predictive value, negative predictive value, and receiver operating characteristic (ROC) analysis. All three radiologists rated MAG images higher than ZOOM images for sensitivity with statistical significance (average value, 92% vs. 87%, P<0.05) and performance by ROC analysis improved with MAG imaging. The confidence rate for diagnosis decision and the assessment of lesion characteristics were also better in MAG images than in ZOOM images with statistical significance (P<0.0001). Digital magnification mammography can enhance diagnostic performance when characterizing microcalcifications. Images zoomed from digital contact mammography cannot serve as an alternative to direct magnification digital mammography. (orig.)

  11. Reconstruction of constitutive parameters in isotropic linear elasticity from noisy full-field measurements

    International Nuclear Information System (INIS)

    Bal, Guillaume; Bellis, Cédric; Imperiale, Sébastien; Monard, François

    2014-01-01

    Within the framework of linear elasticity we assume the availability of internal full-field measurements of the continuum deformations of a non-homogeneous isotropic solid. The aim is the quantitative reconstruction of the associated moduli. A simple gradient system for the sought constitutive parameters is derived algebraically from the momentum equation, whose coefficients are expressed in terms of the measured displacement fields and their spatial derivatives. Direct integration of this system is discussed to finally demonstrate the inexpediency of such an approach when dealing with noisy data. Upon using polluted measurements, an alternative variational formulation is deployed to invert for the physical parameters. Analysis of this latter inversion procedure provides existence and uniqueness results while the reconstruction stability with respect to the measurements is investigated. As the inversion procedure requires differentiating the measurements twice, a numerical differentiation scheme based on an ad hoc regularization then allows an optimally stable reconstruction of the sought moduli. Numerical results are included to illustrate and assess the performance of the overall approach. (paper)

  12. Actinic imaging of native and programmed defects on a full-field mask

    Energy Technology Data Exchange (ETDEWEB)

    Mochi, I.; Goldberg, K. A.; Fontaine, B. La; Tchikoulaeva, A.; Holfeld, C.

    2010-03-12

    We describe the imaging and characterization of native defects on a full field extreme ultraviolet (EUV) mask, using several reticle and wafer inspection modes. Mask defect images recorded with the SEMA TECH Berkeley Actinic Inspection Tool (AIT), an EUV-wavelength (13.4 nm) actinic microscope, are compared with mask and printed-wafer images collected with scanning electron microscopy (SEM) and deep ultraviolet (DUV) inspection tools. We observed that defects that appear to be opaque in the SEM can be highly transparent to EUV light, and inversely, defects that are mostly transparent to the SEM can be highly opaque to EUV. The nature and composition of these defects, whether they appear on the top surface, within the multilayer coating, or on the substrate as buried bumps or pits, influences both their significance when printed, and their detectability with the available techniques. Actinic inspection quantitatively predicts the characteristics of printed defect images in ways that may not be possible with non-EUV techniques. As a quantitative example, we investigate the main structural characteristics of a buried pit defect based on EUV through-focus imaging.

  13. Fractal analysis of en face tomographic images obtained with full field optical coherence tomography

    Energy Technology Data Exchange (ETDEWEB)

    Gao, Wanrong; Zhu, Yue [Department of Optical Engineering, Nanjing University of Science and Technology, Jiangsu (China)

    2017-03-15

    The quantitative modeling of the imaging signal of pathological areas and healthy areas is necessary to improve the specificity of diagnosis with tomographic en face images obtained with full field optical coherence tomography (FFOCT). In this work, we propose to use the depth-resolved change in the fractal parameter as a quantitative specific biomarker of the stages of disease. The idea is based on the fact that tissue is a random medium and only statistical parameters that characterize tissue structure are appropriate. We successfully relate the imaging signal in FFOCT to the tissue structure in terms of the scattering function and the coherent transfer function of the system. The formula is then used to analyze the ratio of the Fourier transforms of the cancerous tissue to the normal tissue. We found that when the tissue changes from the normal to cancerous the ratio of the spectrum of the index inhomogeneities takes the form of an inverse power law and the changes in the fractal parameter can be determined by estimating slopes of the spectra of the ratio plotted on a log-log scale. The fresh normal and cancer liver tissues were imaged to demonstrate the potential diagnostic value of the method at early stages when there are no significant changes in tissue microstructures. (copyright 2016 by WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim)

  14. Development of PZT-excited stroboscopic shearography for full-field nondestructive evaluation.

    Science.gov (United States)

    Asemani, Hamidreza; Park, Jinwoo; Lee, Jung-Ryul; Soltani, Nasser

    2017-05-01

    Nondestructive evaluation using shearography requires a way to stress the inspection target. This technique is able to directly measure the displacement gradient distribution on the object surface. Shearography visualizes the internal structural damages as the anomalous pattern in the shearograpic fringe pattern. A piezoelectric (PZT) excitation system is able to generate loadings in the vibrational, acoustic, and ultrasonic regimes. In this paper, we propose a PZT-excited stroboscopic shearography. The PZT excitation could generate vibrational loading, a stationary wavefield, and a nonstationary propagation wave to fulfill the external loading requirement of shearography. The sweeping of the PZT excitation frequency, the formation of a standing wave, and a small shearing to suppress the incident wave were powerful controllable tools to detect the defects. The sweeping of the PZT excitation frequency enabled us to determine one of the defect-sensitive frequencies almost in real time. In addition, because the defect sensitive frequencies always existed in wide and plural ranges, the risk of the defect being overlooked by the inspector could be alleviated. The results of evaluation using stroboscopic shearography showed that an artificial 20 mm-diameter defect could be visualized at the excitation frequencies of 5-8 kHz range and 12.5-15.5 kHz range. This technique provided full field reliable and repeatable inspection results. Additionally, the proposed method overcame the important drawback of the time-averaged shearography, being required to identify the resonance vibration frequency sensitive to the defect.

  15. Ellipsoidal capillary as condenser for the BESSY full-field x-ray microscope

    International Nuclear Information System (INIS)

    Guttmann, P; Heim, S; Schneider, G; Zeng, X; Feser, M; Yun, W

    2009-01-01

    The BESSY x-ray microscopy group has developed a new full-field x-ray microscope which employs an advanced x-ray optical concept. Traditionally, zone plate based condensers are used in x-ray microscopes providing an energy resolution of only E/ΔE ≤ 500. In addition, this conventional monochromator concept requires a pinhole close to the sample restricting the available space for tomography applications. In our new BESSY microscope, a standard monochromator beam line provides a high energy resolution of up to 10,000 which permits NEXAFS studies. An elliptically shaped mono-capillary is used to form the hollow cone illumination necessary for sample illumination and to match the aperture of the objective. Calculations regarding the performance and accuracies needed are presented and characterizations of capillaries especially made for the BESSY soft x-ray microscope are shown. For the first time, we demonstrate that glass capillaries are well suited as condensers in the soft x-ray energy domain. Their focusing efficiency was measured to be 80% which is about an order of magnitude higher than the diffraction efficiency of zone plate based condensers.

  16. Hard X-ray Full Field Nano-imaging of Bone and Nanowires at SSRL

    International Nuclear Information System (INIS)

    Andrews, Joy C.; Pianetta, Piero; Meirer, Florian; Chen Jie; Almeida, Eduardo; Meulen, Marjolein C. H. van der; Alwood, Joshua S.; Lee, Cathy; Zhu Jia; Cui Yi

    2010-01-01

    A hard X-ray full field microscope from Xradia Inc. has been installed at SSRL on a 54-pole wiggler end station at beam line 6-2. It has been optimized to operate from 5-14 keV with resolution as high as 30 nm. High quality images are achieved using a vertical beam stabilizer and condenser scanner with high efficiency zone plates with 30 nm outermost zone width. The microscope has been used in Zernike phase contrast, available at 5.4 keV and 8 keV, as well as absorption contrast to image a variety of biological, environmental and materials samples. Calibration of the X-ray attenuation with crystalline apatite enabled quantification of bone density of plate-like and rod-like regions of mouse bone trabecula. 3D tomography of individual lacuna revealed the surrounding cell canaliculi and processes. 3D tomography of chiral branched PbSe nanowires showed orthogonal branches around a central nanowire.

  17. Hard X-ray Full Field Nano-imaging of Bone and Nanowires at SSRL.

    Science.gov (United States)

    Andrews, Joy C; Pianetta, Piero; Meirer, Florian; Chen, Jie; Almeida, Eduardo; van der Meulen, Marjolein C H; Alwood, Joshua S; Lee, Cathy; Zhu, Jia; Cui, Yi

    2010-06-23

    A hard X-ray full field microscope from Xradia Inc. has been installed at SSRL on a 54-pole wiggler end station at beam line 6-2. It has been optimized to operate from 5-14 keV with resolution as high as 30 nm. High quality images are achieved using a vertical beam stabilizer and condenser scanner with high efficiency zone plates with 30 nm outermost zone width. The microscope has been used in Zernike phase contrast, available at 5.4 keV and 8 keV, as well as absorption contrast to image a variety of biological, environmental and materials samples. Calibration of the X-ray attenuation with crystalline apatite enabled quantification of bone density of plate-like and rod-like regions of mouse bone trabecula. 3D tomography of individual lacuna revealed the surrounding cell canaliculi and processes. 3D tomography of chiral branched PbSe nanowires showed orthogonal branches around a central nanowire.

  18. Hard X-ray Full Field Nano-imaging of Bone and Nanowires at SSRL

    Science.gov (United States)

    Andrews, Joy C.; Pianetta, Piero; Meirer, Florian; Chen, Jie; Almeida, Eduardo; van der Meulen, Marjolein C. H.; Alwood, Joshua S.; Lee, Cathy; Zhu, Jia; Cui, Yi

    2010-06-01

    A hard X-ray full field microscope from Xradia Inc. has been installed at SSRL on a 54-pole wiggler end station at beam line 6-2. It has been optimized to operate from 5-14 keV with resolution as high as 30 nm. High quality images are achieved using a vertical beam stabilizer and condenser scanner with high efficiency zone plates with 30 nm outermost zone width. The microscope has been used in Zernike phase contrast, available at 5.4 keV and 8 keV, as well as absorption contrast to image a variety of biological, environmental and materials samples. Calibration of the X-ray attenuation with crystalline apatite enabled quantification of bone density of plate-like and rod-like regions of mouse bone trabecula. 3D tomography of individual lacuna revealed the surrounding cell canaliculi and processes. 3D tomography of chiral branched PbSe nanowires showed orthogonal branches around a central nanowire.

  19. Numerical correction of distorted images in full-field optical coherence tomography

    Science.gov (United States)

    Min, Gihyeon; Kim, Ju Wan; Choi, Woo June; Lee, Byeong Ha

    2012-03-01

    We propose a numerical method which can numerically correct the distorted en face images obtained with a full field optical coherence tomography (FF-OCT) system. It is shown that the FF-OCT image of the deep region of a biological sample is easily blurred or degraded because the sample has a refractive index (RI) much higher than its surrounding medium in general. It is analyzed that the focal plane of the imaging system is segregated from the imaging plane of the coherence-gated system due to the RI mismatch. This image-blurring phenomenon is experimentally confirmed by imaging the chrome pattern of a resolution test target through its glass substrate in water. Moreover, we demonstrate that the blurred image can be appreciably corrected by using the numerical correction process based on the Fresnel-Kirchhoff diffraction theory. The proposed correction method is applied to enhance the image of a human hair, which permits the distinct identification of the melanin granules inside the cortex layer of the hair shaft.

  20. Skin cancer margin analysis within minutes with full-field OCT (Conference Presentation)

    Science.gov (United States)

    Dalimier, Eugénie; Ogrich, Lauren; Morales, Diego; Cusack, Carrie Ann; Abdelmalek, Mark; Boccara, Claude; Durkin, John

    2017-02-01

    Non-melanoma skin cancer (NMSC) is the most common cancer. Treatment consists of surgical removal of the skin cancer. Traditional excision involves the removal of the visible skin cancer with a significant margin of normal skin. On cosmetically sensitive areas, Mohs micrographic tissue is the standard of care. Mohs uses intraoperative microscopic margin assessment which minimizes the surgical defect and can help reduce the recurrence rate by a factor of 3. The current Mohs technique relies on frozen section tissue slide preparation which significantly lengthens operative time and requires on-site trained histotechnicians. Full-Field Optical Coherence Tomography (FFOCT) is a novel optical imaging technique which provides a quick and efficient method to visualize cancerous areas in minutes, without any preparation or destruction of the tissue. This study aimed to evaluate the potential of FFOCT for the analysis of skin cancer margins during Mohs surgery. Over 150 images of Mohs specimens were acquired intraoperatively with FFOCT before frozen section analysis. The imaging procedure took less than 5 minutes for each specimen. No artifacts on histological preparation were found arising from FFOCT manipulation; however frozen section artifact was readily seen on FFOCT. An atlas was established with FFOCT images and corresponding histological slides to reveal FFOCT reading criteria of normal and cancerous structures. Blind analysis showed high concordance between FFOCT and histology. FFOCT can potentially reduce recurrence rates while maintaining short surgery times, optimize clinical workflow, and decrease healthcare costs. For the patient, this translates into smaller infection risk, decreased stress, and better comfort.

  1. High resolution in-vivo imaging of skin with full field optical coherence tomography

    Science.gov (United States)

    Dalimier, E.; Bruhat, Alexis; Grieve, K.; Harms, F.; Martins, F.; Boccara, C.

    2014-03-01

    Full-field OCT (FFOCT) has the ability to provide en-face images with a very good axial sectioning as well as a very high transverse resolution (about 1 microns in all directions). Therefore it offers the possibility to visualize biological tissues with very high resolution both on the axial native view, and on vertical reconstructed sections. Here we investigated the potential dermatological applications of in-vivo skin imaging with FFOCT. A commercial FFOCT device was adapted for the in-vivo acquisition of stacks of images on the arm, hand and finger. Several subjects of different benign and pathological skin conditions were tested. The images allowed measurement of the stratum corneum and epidermis thicknesses, measurement of the stratum corneum refractive index, size measurement and count of the keratinocytes, visualization of the dermal-epidermal junction, and visualization of the melanin granules and of the melanocytes. Skins with different pigmentations could be discriminated and skin pathologies such as eczema could be identified. The very high resolution offered by FFOCT both on axial native images and vertical reconstructed sections allows for the visualization and measurement of a set of parameters useful for cosmetology and dermatology. In particular, FFOCT is a potential tool for the understanding and monitoring of skin hydration and pigmentation, as well as skin inflammation.

  2. Improved linearity using harmonic error rejection in a full-field range imaging system

    Science.gov (United States)

    Payne, Andrew D.; Dorrington, Adrian A.; Cree, Michael J.; Carnegie, Dale A.

    2008-02-01

    Full field range imaging cameras are used to simultaneously measure the distance for every pixel in a given scene using an intensity modulated illumination source and a gain modulated receiver array. The light is reflected from an object in the scene, and the modulation envelope experiences a phase shift proportional to the target distance. Ideally the waveforms are sinusoidal, allowing the phase, and hence object range, to be determined from four measurements using an arctangent function. In practice these waveforms are often not perfectly sinusoidal, and in some cases square waveforms are instead used to simplify the electronic drive requirements. The waveforms therefore commonly contain odd harmonics which contribute a nonlinear error to the phase determination, and therefore an error in the range measurement. We have developed a unique sampling method to cancel the effect of these harmonics, with the results showing an order of magnitude improvement in the measurement linearity without the need for calibration or lookup tables, while the acquisition time remains unchanged. The technique can be applied to existing range imaging systems without having to change or modify the complex illumination or sensor systems, instead only requiring a change to the signal generation and timing electronics.

  3. Toward 1-mm depth precision with a solid state full-field range imaging system

    Science.gov (United States)

    Dorrington, Adrian A.; Carnegie, Dale A.; Cree, Michael J.

    2006-02-01

    Previously, we demonstrated a novel heterodyne based solid-state full-field range-finding imaging system. This system is comprised of modulated LED illumination, a modulated image intensifier, and a digital video camera. A 10 MHz drive is provided with 1 Hz difference between the LEDs and image intensifier. A sequence of images of the resulting beating intensifier output are captured and processed to determine phase and hence distance to the object for each pixel. In a previous publication, we detailed results showing a one-sigma precision of 15 mm to 30 mm (depending on signal strength). Furthermore, we identified the limitations of the system and potential improvements that were expected to result in a range precision in the order of 1 mm. These primarily include increasing the operating frequency and improving optical coupling and sensitivity. In this paper, we report on the implementation of these improvements and the new system characteristics. We also comment on the factors that are important for high precision image ranging and present configuration strategies for best performance. Ranging with sub-millimeter precision is demonstrated by imaging a planar surface and calculating the deviations from a planar fit. The results are also illustrated graphically by imaging a garden gnome.

  4. On the use of a penalized least squares method to process kinematic full-field measurements

    International Nuclear Information System (INIS)

    Moulart, Raphaël; Rotinat, René

    2014-01-01

    This work is aimed at exploring the performances of an alternative procedure to smooth and differentiate full-field displacement measurements. After recalling the strategies currently used by the experimental mechanics community, a short overview of the available smoothing algorithms is drawn up and the requirements that such an algorithm has to fulfil to be applicable to process kinematic measurements are listed. A comparative study of the chosen algorithm is performed including the 2D penalized least squares method and two other commonly implemented strategies. The results obtained by penalized least squares are comparable in terms of quality to those produced by the two other algorithms, while the penalized least squares method appears to be the fastest and the most flexible. Unlike both the other considered methods, it is possible with penalized least squares to automatically choose the parameter governing the amount of smoothing to apply. Unfortunately, it appears that this automation is not suitable for the proposed application since it does not lead to optimal strain maps. Finally, it is possible with this technique to perform the derivation to obtain strain maps before smoothing them (while the smoothing is normally applied to displacement maps before the differentiation), which can lead in some cases to a more effective reconstruction of the strain fields. (paper)

  5. Computer-aided detection system applied to full-field digital mammograms

    International Nuclear Information System (INIS)

    Vega Bolivar, Alfonso; Sanchez Gomez, Sonia; Merino, Paula; Alonso-Bartolome, Pilar; Ortega Garcia, Estrella; Munoz Cacho, Pedro; Hoffmeister, Jeffrey W.

    2010-01-01

    Background: Although mammography remains the mainstay for breast cancer screening, it is an imperfect examination with a sensitivity of 75-92% for breast cancer. Computer-aided detection (CAD) has been developed to improve mammographic detection of breast cancer. Purpose: To retrospectively estimate CAD sensitivity and false-positive rate with full-field digital mammograms (FFDMs). Material and Methods: CAD was used to evaluate 151 cases of ductal carcinoma in situ (DCIS) (n=48) and invasive breast cancer (n=103) detected with FFDM. Retrospectively, CAD sensitivity was estimated based on breast density, mammographic presentation, histopathology type, and lesion size. CAD false-positive rate was estimated with screening FFDMs from 200 women. Results: CAD detected 93% (141/151) of cancer cases: 97% (28/29) in fatty breasts, 94% (81/86) in breasts containing scattered fibroglandular densities, 90% (28/31) in heterogeneously dense breasts, and 80% (4/5) in extremely dense breasts. CAD detected 98% (54/55) of cancers manifesting as calcifications, 89% (74/83) as masses, and 100% (13/13) as mixed masses and calcifications. CAD detected 92% (73/79) of invasive ductal carcinomas, 89% (8/9) of invasive lobular carcinomas, 93% (14/15) of other invasive carcinomas, and 96% (46/48) of DCIS. CAD sensitivity for cancers 1-10 mm was 87% (47/54); 11-20 mm, 99% (70/71); 21-30 mm, 86% (12/14); and larger than 30 mm, 100% (12/12). The CAD false-positive rate was 2.5 marks per case. Conclusion: CAD with FFDM showed a high sensitivity in identifying cancers manifesting as calcifications or masses. CAD sensitivity was maintained in small lesions (1-20 mm) and invasive lobular carcinomas, which have lower mammographic sensitivity

  6. Magnetic imaging with full-field soft X-ray microscopies

    International Nuclear Information System (INIS)

    Fischer, Peter; Im, Mi-Young; Baldasseroni, Chloe; Bordel, Catherine; Hellman, Frances; Lee, Jong-Soo; Fadley, Charles S.

    2013-01-01

    Progress toward a fundamental understanding of magnetism continues to be of great scientific interest and high technological relevance. To control magnetization on the nanoscale, external magnetic fields and spin polarized currents are commonly used. In addition, novel concepts based on spin manipulation by electric fields or photons are emerging which benefit from advances in tailoring complex magnetic materials. Although the nanoscale is at the very origin of magnetic behavior, there is a new trend toward investigating mesoscale magnetic phenomena, thus adding complexity and functionality, both of which will become crucial for future magnetic devices. Advanced analytical tools are thus needed for the characterization of magnetic properties spanning the nano- to the meso-scale. Imaging magnetic structures with high spatial and temporal resolution over a large field of view and in three dimensions is therefore a key challenge. A variety of spectromicroscopic techniques address this challenge by taking advantage of variable-polarization soft X-rays, thus enabling X-ray dichroism effects provide magnetic contrast. These techniques are also capable of quantifying in an element-, valence- and site-sensitive way the basic properties of ferro(i)- and antiferro-magnetic systems, such as spin and orbital moments, spin configurations from the nano- to the meso-scale and spin dynamics with sub-ns time resolution. This paper reviews current achievements and outlines future trends with one of these spectromicroscopies, magnetic full field transmission soft X-ray microscopy (MTXM) using a few selected examples of recent research on nano- and meso-scale magnetic phenomena. The complementarity of MTXM to X-ray photoemission electron microscopy (X-PEEM) is also emphasized

  7. Magnetic imaging with full-field soft X-ray microscopies

    Energy Technology Data Exchange (ETDEWEB)

    Fischer, Peter, E-mail: PJFischer@lbl.gov [Center for X-ray Optics, Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Berkeley, CA 94720 (United States); Im, Mi-Young [Center for X-ray Optics, Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Berkeley, CA 94720 (United States); Baldasseroni, Chloe [Department of Materials Science and Engineering, University of California Berkeley, Berkeley, CA 94720 (United States); Bordel, Catherine; Hellman, Frances [Department of Physics, University of California Berkeley, Berkeley, CA 94720 (United States); Material Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94270 (United States); Lee, Jong-Soo [Department of Energy Systems Engineering, Daegu Gyeongbuk Institute of Science and Technology (DGIST), Daegu 711-873 (Korea, Republic of); Fadley, Charles S. [Department of Physics, University of California Davis, Davis, CA 95616 (United States); Material Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94270 (United States)

    2013-08-15

    Progress toward a fundamental understanding of magnetism continues to be of great scientific interest and high technological relevance. To control magnetization on the nanoscale, external magnetic fields and spin polarized currents are commonly used. In addition, novel concepts based on spin manipulation by electric fields or photons are emerging which benefit from advances in tailoring complex magnetic materials. Although the nanoscale is at the very origin of magnetic behavior, there is a new trend toward investigating mesoscale magnetic phenomena, thus adding complexity and functionality, both of which will become crucial for future magnetic devices. Advanced analytical tools are thus needed for the characterization of magnetic properties spanning the nano- to the meso-scale. Imaging magnetic structures with high spatial and temporal resolution over a large field of view and in three dimensions is therefore a key challenge. A variety of spectromicroscopic techniques address this challenge by taking advantage of variable-polarization soft X-rays, thus enabling X-ray dichroism effects provide magnetic contrast. These techniques are also capable of quantifying in an element-, valence- and site-sensitive way the basic properties of ferro(i)- and antiferro-magnetic systems, such as spin and orbital moments, spin configurations from the nano- to the meso-scale and spin dynamics with sub-ns time resolution. This paper reviews current achievements and outlines future trends with one of these spectromicroscopies, magnetic full field transmission soft X-ray microscopy (MTXM) using a few selected examples of recent research on nano- and meso-scale magnetic phenomena. The complementarity of MTXM to X-ray photoemission electron microscopy (X-PEEM) is also emphasized.

  8. Comparison of tissue equalization, and premium view post-processing methods in full field digital mammography

    Energy Technology Data Exchange (ETDEWEB)

    Chen Baoying, E-mail: chenby128@yahoo.co [Department of Radiology, Tangdu Hospital, Fourth Military Medical University, Xinsi Road 1, 710038 Xi' an, Shaanxi (China); Wang Wei; Huang Jin; Zhao Ming; Cui Guangbin [Department of Radiology, Tangdu Hospital, Fourth Military Medical University, Xinsi Road 1, 710038 Xi' an, Shaanxi (China); Xu Jing [Cell Engineering Research Centre and Department of Cell Biology, State Key Laboratory of Cancer Biology, Fourth Military Medical University, Changle West Road 169, 710032 Xi' an, Shaanxi (China); Guo Wei; Du Pang; Li Pei [Department of Radiology, Tangdu Hospital, Fourth Military Medical University, Xinsi Road 1, 710038 Xi' an, Shaanxi (China); Yu Jun, E-mail: pclamper@163.co [Department of Preclinical Experiment Center, Fourth Military Medical University, Changle West Road 169, 710032 Xi' an, Shaanxi (China)

    2010-10-15

    Objective: To retrospectively evaluate the diagnostic abilities of 2 post-processing methods provided by GE Senographe DS system, tissue equalization (TE) and premium view (PV) in full field digital mammography (FFDM). Materials and methods: In accordance with the ethical standards of the World Medical Association, this study was approved by regional ethics committee and signed informed patient consents were obtained. We retrospectively reviewed digital mammograms from 101 women (mean age, 47 years; range, 23-81 years) in the modes of TE and PV, respectively. Three radiologists, fully blinded to the post-processing methods, all patient clinical information and histologic results, read images by using objective image interpretation criteria for diagnostic information end points such as lesion border delineation, definition of disease extent, visualization of internal and surrounding morphologic features of the lesions. Also, overall diagnostic impression in terms of lesion conspicuity, detectability and diagnostic confidence was assessed. Between-group comparisons were performed with Wilcoxon signed rank test. Results: Readers 1, 2, and 3 demonstrated significant overall better impression of PV in 29, 27, and 24 patients, compared with that for TE in 12, 13, and 11 patients, respectively (p < 0.05). Significant (p < 0.05) better impression of PV was also demonstrated for diagnostic information end points. Importantly, PV proved to be more sensitive than TE while detecting malignant lesions in dense breast rather than benign lesions and malignancy in non-dense breast (p < 0.01). Conclusion: PV compared with TE provides marked better diagnostic information in FFDM, particularly for patients with malignancy in dense breast.

  9. Full field reservoir modeling of shale assets using advanced data-driven analytics

    Directory of Open Access Journals (Sweden)

    Soodabeh Esmaili

    2016-01-01

    Full Text Available Hydrocarbon production from shale has attracted much attention in the recent years. When applied to this prolific and hydrocarbon rich resource plays, our understanding of the complexities of the flow mechanism (sorption process and flow behavior in complex fracture systems - induced or natural leaves much to be desired. In this paper, we present and discuss a novel approach to modeling, history matching of hydrocarbon production from a Marcellus shale asset in southwestern Pennsylvania using advanced data mining, pattern recognition and machine learning technologies. In this new approach instead of imposing our understanding of the flow mechanism, the impact of multi-stage hydraulic fractures, and the production process on the reservoir model, we allow the production history, well log, completion and hydraulic fracturing data to guide our model and determine its behavior. The uniqueness of this technology is that it incorporates the so-called “hard data” directly into the reservoir model, so that the model can be used to optimize the hydraulic fracture process. The “hard data” refers to field measurements during the hydraulic fracturing process such as fluid and proppant type and amount, injection pressure and rate as well as proppant concentration. This novel approach contrasts with the current industry focus on the use of “soft data” (non-measured, interpretive data such as frac length, width, height and conductivity in the reservoir models. The study focuses on a Marcellus shale asset that includes 135 wells with multiple pads, different landing targets, well length and reservoir properties. The full field history matching process was successfully completed using this data driven approach thus capturing the production behavior with acceptable accuracy for individual wells and for the entire asset.

  10. Full-field digital mammography versus computed radiology mammography: comparison in image quality and radiation dose

    International Nuclear Information System (INIS)

    Zhao Yongxia; Song Shaojuan; Liu Chuanya; Qi Hengtao; Qin Weichang

    2008-01-01

    Objective: To investigate the differences in image quality and radiation dose between full- field digital mammography (FFDM) system and compute radiology mammography (CRM) system. Methods: The ALVIM mammographic phantom was exposed by FFDM system with automatic exposure control (AEC) and then exposed by CRM system with the unique imaging plank on the same condition. The FFDM system applied the same kV value and the different mAs values (14, 16, 18, 22 and 24 mAs), and the emission skin dose (ESD) and the average gland dose (AGD) were recorded for the above-mentioned exposure factors. All images were read by five experienced radiologists under the same condition and judged based on 5-point scales. And then receive operating characteristic (ROC) curve was drawn and the probability (P det ) values were calculated. The data were statistically processed with ANOVA. Results: The P det values of calcifications and lesion lump were higher with FFDM system than with CRM system at the same dose (1.36 mGy). Especially, for microcalcifications and lesion lump, the largest difference of the P det value was 0.215, and that of lesion lump was 0.245. In comparison with CRM system, the radiation dose of FFDM system could be reduced at the same P det value. The ESD value was reduced by 26%, and the ACD value was reduced by 41%. When the mAs value exceed AEC value, the P det value almost had no change, though the radiation dose was increased. Conclusions: The detection rates of microcalcifications and lesion lump with FFDM system are proven to be superior to CRM system at the same dose. The radiation dose of FFDM system was less than CRM system for the same image quality. (authors)

  11. Performance analysis of a full-field and full-range swept-source OCT system

    Science.gov (United States)

    Krauter, J.; Boettcher, T.; Körner, K.; Gronle, M.; Osten, W.; Passilly, N.; Froehly, L.; Perrin, S.; Gorecki, C.

    2015-09-01

    In recent years, optical coherence tomography (OCT) became gained importance in medical disciplines like ophthalmology, due to its noninvasive optical imaging technique with micrometer resolution and short measurement time. It enables e. g. the measurement and visualization of the depth structure of the retina. In other medical disciplines like dermatology, histopathological analysis is still the gold standard for skin cancer diagnosis. The EU-funded project VIAMOS (Vertically Integrated Array-type Mirau-based OCT System) proposes a new type of OCT system combined with micro-technologies to provide a hand-held, low-cost and miniaturized OCT system. The concept is a combination of full-field and full-range swept-source OCT (SS-OCT) detection in a multi-channel sensor based on a micro-optical Mirau-interferometer array, which is fabricated by means of wafer fabrication. This paper presents the study of an experimental proof-of-concept OCT system as a one-channel sensor with bulk optics. This sensor is a Linnik-interferometer type with similar optical parameters as the Mirau-interferometer array. A commercial wavelength tunable light source with a center wavelength at 845nm and 50nm spectral bandwidth is used with a camera for parallel OCT A-Scan detection. In addition, the reference microscope objective lens of the Linnik-interferometer is mounted on a piezo-actuated phase-shifter. Phase-shifting interferometry (PSI) techniques are applied for resolving the conjugate complex artifact and consequently contribute to an increase of image quality and depth range. A suppression ratio of the complex conjugate term of 36 dB is shown and a system sensitivity greater than 96 dB could be measured.

  12. Global sensitivity analysis in the identification of cohesive models using full-field kinematic data

    KAUST Repository

    Alfano, Marco; Lubineau, Gilles; Paulino, Glá ucio Hermogenes

    2015-01-01

    Failure of adhesive bonded structures often occurs concurrent with the formation of a non-negligible fracture process zone in front of a macroscopic crack. For this reason, the analysis of damage and fracture is effectively carried out using the cohesive zone model (CZM). The crucial aspect of the CZM approach is the precise determination of the traction-separation relation. Yet it is usually determined empirically, by using calibration procedures combining experimental data, such as load-displacement or crack length data, with finite element simulation of fracture. Thanks to the recent progress in image processing, and the availability of low-cost CCD cameras, it is nowadays relatively easy to access surface displacements across the fracture process zone using for instance Digital Image Correlation (DIC). The rich information provided by correlation techniques prompted the development of versatile inverse parameter identification procedures combining finite element (FE) simulations and full field kinematic data. The focus of the present paper is to assess the effectiveness of these methods in the identification of cohesive zone models. In particular, the analysis is developed in the framework of the variance based global sensitivity analysis. The sensitivity of kinematic data to the sought cohesive properties is explored through the computation of the so-called Sobol sensitivity indexes. The results show that the global sensitivity analysis can help to ascertain the most influential cohesive parameters which need to be incorporated in the identification process. In addition, it is shown that suitable displacement sampling in time and space can lead to optimized measurements for identification purposes.

  13. Full field optical coherence tomography can identify spermatogenesis in a rodent sertoli-cell only model.

    Science.gov (United States)

    Ramasamy, Ranjith; Sterling, Joshua; Manzoor, Maryem; Salamoon, Bekheit; Jain, Manu; Fisher, Erik; Li, Phillip S; Schlegel, Peter N; Mukherjee, Sushmita

    2012-01-01

    Microdissection testicular sperm extraction (micro-TESE) has replaced conventional testis biopsies as a method of choice for obtaining sperm for in vitro fertilization for men with nonobstructive azoospermia. A technical challenge of micro-TESE is that the low magnification inspection of the tubules with a surgical microscope is insufficient to definitively identify sperm-containing tubules, necessitating tissue removal and cytologic assessment. Full field optical coherence tomography (FFOCT) uses white light interference microscopy to generate quick high-resolution tomographic images of fresh (unprocessed and unstained) tissue. Furthermore, by using a nonlaser safe light source (150 W halogen lamp) for tissue illumination, it ensures that the sperm extracted for in vitro fertilization are not photo-damaged or mutagenized. A focal Sertoli-cell only rodent model was created with busulfan injection in adult rats. Ex vivo testicular tissues from both normal and busulfan-treated rats were imaged with a commercial modified FFOCT system, Light-CT™, and the images were correlated with gold standard hematoxylin and eosin staining. Light-CT™ identified spermatogenesis within the seminiferous tubules in freshly excised testicular tissue, without the use of exogenous contrast or fixation. Normal adult rats exhibited tubules with uniform size and shape (diameter 328 ±11 μm). The busulfan-treated animals showed marked heterogeneity in tubular size and shape (diameter 178 ± 35 μm) and only 10% contained sperm within the lumen. FFOCT has the potential to facilitate real-time visualization of spermatogenesis in humans, and aid in micro-TESE for men with infertility.

  14. Full Field X-Ray Fluorescence Imaging Using Micro Pore Optics for Planetary Surface Exploration

    Science.gov (United States)

    Sarrazin, P.; Blake, D. F.; Gailhanou, M.; Walter, P.; Schyns, E.; Marchis, F.; Thompson, K.; Bristow, T.

    2016-01-01

    Many planetary surface processes leave evidence as small features in the sub-millimetre scale. Current planetary X-ray fluorescence spectrometers lack the spatial resolution to analyse such small features as they only provide global analyses of areas greater than 100 mm(exp 2). A micro-XRF spectrometer will be deployed on the NASA Mars 2020 rover to analyse spots as small as 120m. When using its line-scanning capacity combined to perpendicular scanning by the rover arm, elemental maps can be generated. We present a new instrument that provides full-field XRF imaging, alleviating the need for precise positioning and scanning mechanisms. The Mapping X-ray Fluorescence Spectrometer - "Map-X" - will allow elemental imaging with approximately 100µm spatial resolution and simultaneously provide elemental chemistry at the scale where many relict physical, chemical and biological features can be imaged in ancient rocks. The arm-mounted Map-X instrument is placed directly on the surface of an object and held in a fixed position during measurements. A 25x25 mm(exp 2) surface area is uniformly illuminated with X-rays or alpha-particles and gamma-rays. A novel Micro Pore Optic focusses a fraction of the emitted X-ray fluorescence onto a CCD operated at a few frames per second. On board processing allows measuring the energy and coordinates of each X-ray photon collected. Large sets of frames are reduced into 2d histograms used to compute higher level data products such as elemental maps and XRF spectra from selected regions of interest. XRF spectra are processed on the ground to further determine quantitative elemental compositions. The instrument development will be presented with an emphasis on the characterization and modelling of the X-ray focussing Micro Pore Optic. An outlook on possible alternative XRF imaging applications will be discussed.

  15. Impact of full field digital mammography on the classification and mammographic characteristics of interval breast cancers

    Energy Technology Data Exchange (ETDEWEB)

    Knox, Mark, E-mail: marktknox@gmail.com; O’Brien, Angela, E-mail: angelaobrien@doctors.org.uk; Szabó, Endre, E-mail: endrebacsi@freemail.hu; Smith, Clare S., E-mail: csmith@mater.ie; Fenlon, Helen M., E-mail: helen.fenlon@cancerscreening.ie; McNicholas, Michelle M., E-mail: michelle.mcnicholas@cancerscreening.ie; Flanagan, Fidelma L., E-mail: fidelma.flanagan@cancerscreening.ie

    2015-06-15

    Highlights: • Digital mammography has changed the presentation of interval breast cancer. • Less interval breast cancers are associated with microcalcifications following FFDM. • Interval breast cancer audit remains a key feature of any breast screening program. - Abstract: Objective: Full field digital mammography (FFDM) is increasingly replacing screen film mammography (SFM) in breast screening programs. Interval breast cancers are an issue in all screening programs and the purpose of our study is to assess the impact of FFDM on the classification of interval breast cancers at independent blind review and to compare the mammographic features of interval cancers at FFDM and SFM. Materials and methods: This study included 138 cases of interval breast cancer, 76 following an FFDM screening examination and 62 following screening with SFM. The prior screening mammogram was assessed by each of five consultant breast radiologists who were blinded to the site of subsequent cancer. Subsequent review of the diagnostic mammogram was performed and cases were classified as missed, minimal signs, occult or true interval. Mammographic features of the interval cancer at diagnosis and any abnormality identified on the prior screening mammogram were recorded. Results: The percentages of cancers classified as missed at FFDM and SFM did not differ significantly, 10.5% (8 of 76) at FFDM and 8.1% (5 of 62) at SFM (p = .77). There were significantly less interval cancers presenting as microcalcifications (alone or in association with another abnormality) following screening with FFDM, 16% (12 of 76) than following a SFM examination, 32% (20 of 62) (p = .02). Conclusion: Interval breast cancers continue to pose a problem at FFDM. The switch to FFDM has changed the mammographic presentation of interval breast cancer, with less interval cancers presenting in association with microcalcifications.

  16. Comparison of tissue equalization, and premium view post-processing methods in full field digital mammography

    International Nuclear Information System (INIS)

    Chen Baoying; Wang Wei; Huang Jin; Zhao Ming; Cui Guangbin; Xu Jing; Guo Wei; Du Pang; Li Pei; Yu Jun

    2010-01-01

    Objective: To retrospectively evaluate the diagnostic abilities of 2 post-processing methods provided by GE Senographe DS system, tissue equalization (TE) and premium view (PV) in full field digital mammography (FFDM). Materials and methods: In accordance with the ethical standards of the World Medical Association, this study was approved by regional ethics committee and signed informed patient consents were obtained. We retrospectively reviewed digital mammograms from 101 women (mean age, 47 years; range, 23-81 years) in the modes of TE and PV, respectively. Three radiologists, fully blinded to the post-processing methods, all patient clinical information and histologic results, read images by using objective image interpretation criteria for diagnostic information end points such as lesion border delineation, definition of disease extent, visualization of internal and surrounding morphologic features of the lesions. Also, overall diagnostic impression in terms of lesion conspicuity, detectability and diagnostic confidence was assessed. Between-group comparisons were performed with Wilcoxon signed rank test. Results: Readers 1, 2, and 3 demonstrated significant overall better impression of PV in 29, 27, and 24 patients, compared with that for TE in 12, 13, and 11 patients, respectively (p < 0.05). Significant (p < 0.05) better impression of PV was also demonstrated for diagnostic information end points. Importantly, PV proved to be more sensitive than TE while detecting malignant lesions in dense breast rather than benign lesions and malignancy in non-dense breast (p < 0.01). Conclusion: PV compared with TE provides marked better diagnostic information in FFDM, particularly for patients with malignancy in dense breast.

  17. Computer-aided detection system applied to full-field digital mammograms

    Energy Technology Data Exchange (ETDEWEB)

    Vega Bolivar, Alfonso; Sanchez Gomez, Sonia; Merino, Paula; Alonso-Bartolome, Pilar; Ortega Garcia, Estrella (Dept. of Radiology, Univ. Marques of Valdecilla Hospital, Santander (Spain)), e-mail: avegab@telefonica.net; Munoz Cacho, Pedro (Dept. of Statistics, Univ. Marques of Valdecilla Hospital, Santander (Spain)); Hoffmeister, Jeffrey W. (iCAD, Inc., Nashua, NH (United States))

    2010-12-15

    Background: Although mammography remains the mainstay for breast cancer screening, it is an imperfect examination with a sensitivity of 75-92% for breast cancer. Computer-aided detection (CAD) has been developed to improve mammographic detection of breast cancer. Purpose: To retrospectively estimate CAD sensitivity and false-positive rate with full-field digital mammograms (FFDMs). Material and Methods: CAD was used to evaluate 151 cases of ductal carcinoma in situ (DCIS) (n=48) and invasive breast cancer (n=103) detected with FFDM. Retrospectively, CAD sensitivity was estimated based on breast density, mammographic presentation, histopathology type, and lesion size. CAD false-positive rate was estimated with screening FFDMs from 200 women. Results: CAD detected 93% (141/151) of cancer cases: 97% (28/29) in fatty breasts, 94% (81/86) in breasts containing scattered fibroglandular densities, 90% (28/31) in heterogeneously dense breasts, and 80% (4/5) in extremely dense breasts. CAD detected 98% (54/55) of cancers manifesting as calcifications, 89% (74/83) as masses, and 100% (13/13) as mixed masses and calcifications. CAD detected 92% (73/79) of invasive ductal carcinomas, 89% (8/9) of invasive lobular carcinomas, 93% (14/15) of other invasive carcinomas, and 96% (46/48) of DCIS. CAD sensitivity for cancers 1-10 mm was 87% (47/54); 11-20 mm, 99% (70/71); 21-30 mm, 86% (12/14); and larger than 30 mm, 100% (12/12). The CAD false-positive rate was 2.5 marks per case. Conclusion: CAD with FFDM showed a high sensitivity in identifying cancers manifesting as calcifications or masses. CAD sensitivity was maintained in small lesions (1-20 mm) and invasive lobular carcinomas, which have lower mammographic sensitivity

  18. ARTROC—a readout ASIC for GEM-based full-field XRF imaging system

    Science.gov (United States)

    Fiutowski, T.; Koperny, S.; Łach, B.; Mindur, B.; Świentek, K.; Wiącek, P.; Dąbrowski, W.

    2017-12-01

    In the paper we report on development of an Application Specific Integrated Circuit (ASIC), called ARTROC, being part of a full-field X-ray fluorescence spectroscopy (XRF) imaging system equipped with a standard three stage Gas Electron Multiplier (GEM) detector of 10×10 cm2 area. The ARTROC consists of 64 independent channels, allowing for simultaneous recording of the amplitudes (energy sub-channel) and time stamps (timing sub-channel) of incoming signals. Thanks to the implemented token-based read out of derandomizing buffers, the ASIC also provides data sparsification and full zero suppression. Reconstruction of the hit positions is performed in an external data acquisition system by matching the time stamps of signals recorded in X- and Y-strips. The amplitude information is used for centre of gravity finding in clusters of signals on neighbouring strips belonging to the same detection events. The ASIC could work in one of six gain modes and one of two speed modes. In a slower mode the maximum count rate per channel is 105/s while in a faster mode it is three times higher. The ARTROC comprises also input protection circuits against possible random discharges inside active detector volume, so it can be used without any additional input components. The ASIC has been designed in 350 nm CMOS process. The basic functionality and parameters have been evaluated using the testability functions implemented in the ASIC design. The ASIC has been also tested in a fully equipped GEM detector set-up with X-rays source.

  19. Global sensitivity analysis in the identification of cohesive models using full-field kinematic data

    KAUST Repository

    Alfano, Marco

    2015-03-01

    Failure of adhesive bonded structures often occurs concurrent with the formation of a non-negligible fracture process zone in front of a macroscopic crack. For this reason, the analysis of damage and fracture is effectively carried out using the cohesive zone model (CZM). The crucial aspect of the CZM approach is the precise determination of the traction-separation relation. Yet it is usually determined empirically, by using calibration procedures combining experimental data, such as load-displacement or crack length data, with finite element simulation of fracture. Thanks to the recent progress in image processing, and the availability of low-cost CCD cameras, it is nowadays relatively easy to access surface displacements across the fracture process zone using for instance Digital Image Correlation (DIC). The rich information provided by correlation techniques prompted the development of versatile inverse parameter identification procedures combining finite element (FE) simulations and full field kinematic data. The focus of the present paper is to assess the effectiveness of these methods in the identification of cohesive zone models. In particular, the analysis is developed in the framework of the variance based global sensitivity analysis. The sensitivity of kinematic data to the sought cohesive properties is explored through the computation of the so-called Sobol sensitivity indexes. The results show that the global sensitivity analysis can help to ascertain the most influential cohesive parameters which need to be incorporated in the identification process. In addition, it is shown that suitable displacement sampling in time and space can lead to optimized measurements for identification purposes.

  20. Postoperative changes in the full-field electroretinogram following sevoflurane anaesthesia.

    LENUS (Irish Health Repository)

    Iohom, G

    2012-02-03

    BACKGROUND AND OBJECTIVE: We tested the hypothesis that disturbances of the visual pathway persist following general anaesthesia, even after normal clinical discharge criteria have been met. METHODS: We performed full-field flash electroretinography in the right eye of 10 unpremedicated ASA I patients who underwent N2O\\/sevoflurane anaesthesia. Electroretinograms were recorded preoperatively, immediately after discharge from the recovery room and 2 h after discontinuation of sevoflurane. The time at which postanaesthesia discharge score first exceeded 9 was also noted. Data were analysed using paired, one-tailed Student\\'s t-test. RESULTS: Latency of the b-wave on the photopic electroretinogram was greater at each postoperative time point (30.5 +\\/- 0.9 and 30 +\\/- 1.3 ms), compared to preoperative values (29.2 +\\/- 0.8 ms, P < 0.001 and P = 0.04, respectively). The A-B amplitude of the b-wave was less postoperatively (220.3 +\\/- 52.7 and 210.3 +\\/- 42.7 pV) compared to values before operation (248.1 +\\/- 57.6 microV, P = 0.03 and P = 0.01, respectively). Oscillatory potential latencies were greater at each postoperative time point (21.4 +\\/- 0.5 and 20.8 +\\/- 0.6 ms) compared to before operation (20.4 +\\/- 0.4 ms, P < 0.001 and P = 0.03, respectively). Oscillatory potential amplitudes were less at the first postoperative time point (17.5 +\\/- 6.1 microV), compared to preoperative values (22 +\\/- 6.4 microV, P = 0.04). CONCLUSIONS: Postoperative electroretinogram abnormalities are consistently present in patients who have undergone N2O\\/sevoflurane anaesthesia. These abnormalities persist beyond the time at which standard clinical discharge criteria have been met.

  1. Quality control and primo-diagnosis of transurethral bladder resections with full-field OCT

    Science.gov (United States)

    Montagne, P.; Ducesne, I.; Anract, J.; Yang, C.; Sibony, M.; Beuvon, F.; Delongchamps, N. B.; Dalimier, E.

    2017-02-01

    Transurethral resections are commonly used for bladder cancer diagnosis, treatment and follow-up. Cancer staging relies largely on the analysis of muscle in the resections; however, muscle presence is uncertain at the time of the resection. An extemporaneous quality control tool would be of great use to certify the presence of muscle in the resection, and potentially formulate a primo-diagnosis, in order to ensure optimum patient care. Full-field optical coherence tomography (FFOCT) offers a fast and non-destructive method of obtaining images of biological tissues at ultrahigh resolution (1μm in all 3 directions), approaching traditional histological sections. This study aimed to evaluate the potential of FFOCT for the quality control and the primo-diagnosis of transurethral bladder resections. Over 70 transurethral bladder resections were imaged with FFOCT within minutes, shortly after excision, and before histological preparation. Side-by-side comparison with histology allowed to establish reading criteria for the presence of muscle and cancer in particular. Images of 24 specimens were read blindly by three non-pathologists readers: two resident urologists and a junior bio-medical engineer, who were asked to notify the presence of muscle and tumor. Results showed that after appropriate training, 96% accuracy could be obtained on both tumour and muscle detection. FFOCT is a fast and nondestructive imaging technique that provides analysis results concordant with histology. Its implementation as a quality control and primo-diagnosis tool for transurethral bladder resections in the urology suite is feasible and lets envision high value for the patient.

  2. Comparison of dry laser printer versus paper printer in full-field digital mammography.

    Science.gov (United States)

    Liang, Zhigang; Du, Xiangying; Guo, Xiaojuan; Rong, Dongdong; Kang, Ruiying; Mao, Guangyun; Liu, Jiabin; Li, Kuncheng

    2010-04-01

    Paper printers have been used to document radiological findings in some hospitals. It is critical to establish whether paper printers can achieve the same efficacy and quality as dry laser printers for full-field digital mammography (FFDM). To compare the image quality and detection rate of dry laser printers and paper printers for FFDM. Fifty-five cases (25 with single clustered microcalcifications and 30 controls) were selected by a radiologist not participating in the image review. All images were printed on film and paper by one experienced mammography technologist using the processing algorithm routinely used for our mammograms. Two radiologists evaluated hard copies from dry laser printers and paper printers for image quality and detectability of clustered microcalcifications. For the image quality comparisons, agreement between the reviewers was evaluated by means of kappa statistics. The significance of differences between both of the printers was determined using Wilcoxon's signed-rank test. The detection rate of two printing systems was evaluated using receiver operating characteristic (ROC) analysis. From 110 scores (55 patients, two readers) per printer system, the following quality results were achieved for dry laser printer images: 70 (63.6%) were rated as good and 40 (36.4%) as moderate. By contrast, for the paper printer images, 25 scores (22.7%) were rated as good and 85 (77.3%) as moderate. Therefore, the image quality of the dry laser printer was superior to that achieved by the paper printer (P=0.00). The average area-under-the-curve (Az) values for the dry laser printer and the paper printer were 0.991 and 0.805, respectively. The difference was 0.186. Results of ROC analysis showed significant difference in observer performance between the dry laser printer and paper printer (P=0.0015). The performance of dry laser printers is superior to that of paper printers. Paper printers should not be used in FFDM.

  3. Impact of full field digital mammography on the classification and mammographic characteristics of interval breast cancers

    International Nuclear Information System (INIS)

    Knox, Mark; O’Brien, Angela; Szabó, Endre; Smith, Clare S.; Fenlon, Helen M.; McNicholas, Michelle M.; Flanagan, Fidelma L.

    2015-01-01

    Highlights: • Digital mammography has changed the presentation of interval breast cancer. • Less interval breast cancers are associated with microcalcifications following FFDM. • Interval breast cancer audit remains a key feature of any breast screening program. - Abstract: Objective: Full field digital mammography (FFDM) is increasingly replacing screen film mammography (SFM) in breast screening programs. Interval breast cancers are an issue in all screening programs and the purpose of our study is to assess the impact of FFDM on the classification of interval breast cancers at independent blind review and to compare the mammographic features of interval cancers at FFDM and SFM. Materials and methods: This study included 138 cases of interval breast cancer, 76 following an FFDM screening examination and 62 following screening with SFM. The prior screening mammogram was assessed by each of five consultant breast radiologists who were blinded to the site of subsequent cancer. Subsequent review of the diagnostic mammogram was performed and cases were classified as missed, minimal signs, occult or true interval. Mammographic features of the interval cancer at diagnosis and any abnormality identified on the prior screening mammogram were recorded. Results: The percentages of cancers classified as missed at FFDM and SFM did not differ significantly, 10.5% (8 of 76) at FFDM and 8.1% (5 of 62) at SFM (p = .77). There were significantly less interval cancers presenting as microcalcifications (alone or in association with another abnormality) following screening with FFDM, 16% (12 of 76) than following a SFM examination, 32% (20 of 62) (p = .02). Conclusion: Interval breast cancers continue to pose a problem at FFDM. The switch to FFDM has changed the mammographic presentation of interval breast cancer, with less interval cancers presenting in association with microcalcifications

  4. 20-kW solar photovoltaic flat-panel power system for an uninterruptible power-system load in El Paso, Texas. Phase II. System fabrication. Final report October 1, 1979-May 31, 1981

    Energy Technology Data Exchange (ETDEWEB)

    Risser, V.V.

    1981-12-01

    The system plans, construction, integration and test, and performance evaluation are discussed for the photovoltaic power supply at the Newman Power Station in El Paso, Texas. The system consists of 64 parallel-connected panels, each panel containing nine series-connected photovoltaic modules. The system is connected, through power monitoring equipment, to an existing DC bus that supplies uninterruptible power to a computer that controls the power generating equipment. The site is described and possible environmental hazards are assessed. Site preparation and the installation of the photovoltaic panels, electrical cabling, and instrumentation subsystems are described. System testing includes initial system checkout, module performance test, control system test. A training program for operators and maintenance personnel is briefly described, including visual aids. Performance data collection and analysis are described, and actual data are compared with a computer simulation. System drawings are included. (LEW)

  5. Detector evaluation of a prototype amorphous selenium-based full field digital mammography system

    Science.gov (United States)

    Jesneck, Jonathan L.; Saunders, Robert S.; Samei, Ehsan; Xia, Jessie Q.; Lo, Joseph Y.

    2005-04-01

    This study evaluated the physical performance of a selenium-based direct full-field digital mammography prototype detector (Siemens Mammomat NovationDR), including the pixel value vs. exposure linearity, the modulation transfer function (MTF), the normalized noise power spectrum (NNPS), and the detective quantum efficiency (DQE). The current detector is the same model which received an approvable letter from FDA for release to the US market. The results of the current prototype are compared to those of an earlier prototype. Two IEC standard beam qualities (RQA-M2: Mo/Mo, 28 kVp, 2 mm Al; RQA-M4: Mo/Mo, 35 kVp, 2 mm Al) and two additional beam qualities (MW2: W/Rh, 28 kVp, 2 mm Al; MW4: W/Rh, 35 kVp, 2 mm Al) were investigated. To calculate the modulation transfer function (MTF), a 0.1 mm Pt-Ir edge was imaged at each beam quality. Detector pixel values responded linearly against exposure values (R2 0.999). As before, above 6 cycles/mm Mo/Mo MTF was slightly higher along the chest-nipple axis compared to the left-right axis. MTF was comparable to the previously reported prototype, with slightly reduced resolution. The DQE peaks ranged from 0.71 for 3.31 μC/kg (12.83 mR) to 0.4 for 0.48 μC/kg (1.86 mR) at 1.75 cycles/mm for Mo/Mo at 28 kVp. The DQE range for W/Rh at 28 kVP was 0.81 at 2.03 μC/kg (7.87 mR) to 0.50 at 0.50 μC/kg (1.94 mR) at 1 cycle/mm. NNPS tended to increase with greater exposures, while all exposures had a significant low-frequency component. Bloom and detector edge artifacts observed previously were no longer present in this prototype. The new detector shows marked noise improvement, with slightly reduced resolution. There remain artifacts due to imperfect gain calibration, but at a reduced magnitude compared to a prototype detector.

  6. Computer aided detection of clusters of microcalcifications on full field digital mammograms

    International Nuclear Information System (INIS)

    Ge Jun; Sahiner, Berkman; Hadjiiski, Lubomir M.; Chan, H.-P.; Wei Jun; Helvie, Mark A.; Zhou Chuan

    2006-01-01

    We are developing a computer-aided detection (CAD) system to identify microcalcification clusters (MCCs) automatically on full field digital mammograms (FFDMs). The CAD system includes six stages: preprocessing; image enhancement; segmentation of microcalcification candidates; false positive (FP) reduction for individual microcalcifications; regional clustering; and FP reduction for clustered microcalcifications. At the stage of FP reduction for individual microcalcifications, a truncated sum-of-squares error function was used to improve the efficiency and robustness of the training of an artificial neural network in our CAD system for FFDMs. At the stage of FP reduction for clustered microcalcifications, morphological features and features derived from the artificial neural network outputs were extracted from each cluster. Stepwise linear discriminant analysis (LDA) was used to select the features. An LDA classifier was then used to differentiate clustered microcalcifications from FPs. A data set of 96 cases with 192 images was collected at the University of Michigan. This data set contained 96 MCCs, of which 28 clusters were proven by biopsy to be malignant and 68 were proven to be benign. The data set was separated into two independent data sets for training and testing of the CAD system in a cross-validation scheme. When one data set was used to train and validate the convolution neural network (CNN) in our CAD system, the other data set was used to evaluate the detection performance. With the use of a truncated error metric, the training of CNN could be accelerated and the classification performance was improved. The CNN in combination with an LDA classifier could substantially reduce FPs with a small tradeoff in sensitivity. By using the free-response receiver operating characteristic methodology, it was found that our CAD system can achieve a cluster-based sensitivity of 70, 80, and 90 % at 0.21, 0.61, and 1.49 FPs/image, respectively. For case

  7. Screen film vs full-field digital mammography: image quality, detectability and characterization of lesions

    International Nuclear Information System (INIS)

    Obenauer, S.; Luftner-Nagel, S.; Heyden, D. von; Baum, F.; Grabbe, E.; Munzel, U.

    2002-01-01

    The objective of this study was to compare screen-film mammography (SFM) to full-field digital mammography (FFDM) regarding image quality as well as detectability and characterization of lesions using equivalent images of the same patient acquired with both systems. Two mammography units were used, one with a screen-film system (Senographe DMR) and the other with a digital detector (Senographe 2000D, both GEMS). Screen-film and digital mammograms were performed on 55 patients with cytologically or histologically proven tumors on the same day. Together with these, 75 digital mammograms of patients without tumor and the corresponding previous screen-film mammograms not older than 1.5 years were reviewed by three observers in a random order. Contrast, exposure, and the presence of artifacts were evaluated. Different details, such as the skin, the retromamillary region, and the parenchymal structures, were judged according to a three-point ranking scale. Finally, the detectability of microcalcifications and lesions were compared and correlated to histology. Image contrast was judged to be good in 76%, satisfactory in 20%, and unsatisfactory in 4% of screen-film mammograms. Digital mammograms were judged to be good in 99% and unsatisfactory in 1% of cases. Improper exposure of screen-film system occurred in 18% (10% overexposed and 8% underexposed). Digital mammograms were improperly exposed in 4% of all cases but were of acceptable quality after post-processing. Artifacts, most of them of no significance, were found in 78% of screen-film and in none of the digital mammograms. Different anatomical regions, such as the skin, the retromamillary region, and dense parenchymal areas, were better visualized in digital than in screen-film mammography. All malignant tumors were seen by the three radiologists; however, digital mammograms allowed a better characterization of these lesions to the Breast Imaging Reporting and Data System (BI-RADSZZZ;) categories (FFDM better than

  8. Full-field initialized decadal predictions with the MPI earth system model: an initial shock in the North Atlantic

    Science.gov (United States)

    Kröger, Jürgen; Pohlmann, Holger; Sienz, Frank; Marotzke, Jochem; Baehr, Johanna; Köhl, Armin; Modali, Kameswarrao; Polkova, Iuliia; Stammer, Detlef; Vamborg, Freja S. E.; Müller, Wolfgang A.

    2017-12-01

    Our decadal climate prediction system, which is based on the Max-Planck-Institute Earth System Model, is initialized from a coupled assimilation run that utilizes nudging to selected state parameters from reanalyses. We apply full-field nudging in the atmosphere and either full-field or anomaly nudging in the ocean. Full fields from two different ocean reanalyses are considered. This comparison of initialization strategies focuses on the North Atlantic Subpolar Gyre (SPG) region, where the transition from anomaly to full-field nudging reveals large differences in prediction skill for sea surface temperature and ocean heat content (OHC). We show that nudging of temperature and salinity in the ocean modifies OHC and also induces changes in mass and heat transports associated with the ocean flow. In the SPG region, the assimilated OHC signal resembles well OHC from observations, regardless of using full fields or anomalies. The resulting ocean transport, on the other hand, reveals considerable differences between full-field and anomaly nudging. In all assimilation runs, ocean heat transport together with net heat exchange at the surface does not correspond to OHC tendencies, the SPG heat budget is not closed. Discrepancies in the budget in the cases of full-field nudging exceed those in the case of anomaly nudging by a factor of 2-3. The nudging-induced changes in ocean transport continue to be present in the free running hindcasts for up to 5 years, a clear expression of memory in our coupled system. In hindcast mode, on annual to inter-annual scales, ocean heat transport is the dominant driver of SPG OHC. Thus, we ascribe a significant reduction in OHC prediction skill when using full-field instead of anomaly initialization to an initialization shock resulting from the poor initialization of the ocean flow.

  9. Non-destructive analysis of flake properties in automotive paints with full-field optical coherence tomography and 3D segmentation.

    Science.gov (United States)

    Zhang, Jinke; Williams, Bryan M; Lawman, Samuel; Atkinson, David; Zhang, Zijian; Shen, Yaochun; Zheng, Yalin

    2017-08-07

    Automotive coating systems are designed to protect vehicle bodies from corrosion and enhance their aesthetic value. The number, size and orientation of small metallic flakes in the base coat of the paint has a significant effect on the appearance of automotive bodies. It is important for quality assurance (QA) to be able to measure the properties of these small flakes, which are approximately 10μm in radius, yet current QA techniques are limited to measuring layer thickness. We design and develop a time-domain (TD) full-field (FF) optical coherence tomography (OCT) system to scan automotive panels volumetrically, non-destructively and without contact. We develop and integrate a segmentation method to automatically distinguish flakes and allow measurement of their properties. We test our integrated system on nine sections of five panels and demonstrate that this integrated approach can characterise small flakes in automotive coating systems in 3D, calculating the number, size and orientation accurately and consistently. This has the potential to significantly impact QA testing in the automotive industry.

  10. Panel Analysis

    DEFF Research Database (Denmark)

    Brænder, Morten; Andersen, Lotte Bøgh

    2014-01-01

    Based on our 2013-article, ”Does Deployment to War Affect Soldiers' Public Service Motivation – A Panel Study of Soldiers Before and After their Service in Afghanistan”, we present Panel Analysis as a methodological discipline. Panels consist of multiple units of analysis, observed at two or more...... in research settings where it is not possible to distribute units of analysis randomly or where the independent variables cannot be manipulated. The greatest disadvantage in regard to using panel studies is that data may be difficult to obtain. This is most clearly vivid in regard to the use of panel surveys...... points in time. In comparison with traditional cross-sectional studies, the advantage of using panel studies is that the time dimension enables us to study effects. Whereas experimental designs may have a clear advantage in regard to causal inference, the strength of panel studies is difficult to match...

  11. JTEC panel on display technologies in Japan

    Science.gov (United States)

    Tannas, Lawrence E., Jr.; Glenn, William E.; Credelle, Thomas; Doane, J. William; Firester, Arthur H.; Thompson, Malcolm

    1992-01-01

    This report is one in a series of reports that describes research and development efforts in Japan in the area of display technologies. The following are included in this report: flat panel displays (technical findings, liquid crystal display development and production, large flat panel displays (FPD's), electroluminescent displays and plasma panels, infrastructure in Japan's FPD industry, market and projected sales, and new a-Si active matrix liquid crystal display (AMLCD) factory); materials for flat panel displays (liquid crystal materials, and light-emissive display materials); manufacturing and infrastructure of active matrix liquid crystal displays (manufacturing logistics and equipment); passive matrix liquid crystal displays (LCD basics, twisted nematics LCD's, supertwisted nematic LCD's, ferroelectric LCD's, and a comparison of passive matrix LCD technology); active matrix technology (basic active matrix technology, investment environment, amorphous silicon, polysilicon, and commercial products and prototypes); and projection displays (comparison of Japanese and U.S. display research, and technical evaluation of work).

  12. The effect of oblique angle of sound incidence, realistic edge conditions, curvature and in-plane panel stresses on the noise reduction characteristics of general aviation type panels

    Science.gov (United States)

    Grosveld, F.; Lameris, J.; Dunn, D.

    1979-01-01

    Experiments and a theoretical analysis were conducted to predict the noise reduction of inclined and curved panels. These predictions are compared to the experimental results with reasonable agreement between theory and experiment for panels under an oblique angle of sound incidence. Theoretical as well as experimental results indicate a big increase in noise reduction when a flat test panel is curved. Further curving the panel slightly decreases the noise reduction. Riveted flat panels are shown to give a higher noise reduction in the stiffness-controlled frequency region, while bonded panels are superior in this region when the test panel is curved. Experimentally measured noise reduction characteristics of flat aluminum panels with uniaxial in-plane stresses are presented and discussed. These test results indicate an important improvement in the noise reduction of these panels in the frequency range below the fundamental panel/cavity frequency.

  13. Creating flat design websites

    CERN Document Server

    Pratas, Antonio

    2014-01-01

    This book contains practical, step-by-step tutorials along with plenty of explanation about designing your flat website. Each section is introduced sequentially, building up your web design skills and completing your website.Creating Flat Design Websites is ideal for you if you are starting on your web development journey, but this book will also benefit seasoned developers wanting to start developing in flat.

  14. Full-field fabric stress mapping by micro Raman spectroscopy in a yarn push-out test.

    Science.gov (United States)

    Lei, Z K; Qin, F Y; Fang, Q C; Bai, R X; Qiu, W; Chen, X

    2018-02-01

    The full-field stress distribution of a two-dimensional plain fabric was mapped using micro Raman spectroscopy (MRS) through a novel yarn push-out test, simulating a quasi-static projectile impact on the fabric. The stress-strain relationship for a single yarn was established using a digital image correlation method in a single-yarn tensile test. The relationship between Raman peak shift and aramid Kevlar 49 yarn stress was established using MRS in a single-yarn tensile test. An out-of-plane loading test was conducted on an aramid Kevlar 49 plain fabric, and the yarn stress was measured using MRS. From the full-field fabric stress distribution, it can be observed that there is a cross-shaped distribution of high yarn stress; this result would be helpful in further studies on load transfer on a fabric during a projectile impact.

  15. Full-field ultrasonic inspection for a composite sandwich plate skin-core debonding detection using laser-based ultrasonics

    Science.gov (United States)

    Chong, See Yenn; Victor, Jared J.; Todd, Michael D.

    2017-04-01

    In this paper, a full-field ultrasonic guided wave method is proposed to inspect a composite sandwich specimen made for an aircraft engine nacelle. The back skin/core interface of the specimen is built with two fabricated disbond defects (diameters of 12.7 mm and 25.4 mm) by removing areas of the adhesive used to bond the back skin to the core. A laser ultrasonic interrogation system (LUIS) incorporated with a disbond detection algorithm is developed. The system consists of a 1-kHz laser ultrasonic scanning system and a single fixed ultrasonic sensor to interrogate ultrasonic guided waves in the sandwich specimen. The interest area of 400 mm × 400 mm is scanned at a 0.5 mm scan interval. The corresponding full-field ultrasonic data is obtained and generated in the three-dimensional (3-D) space-time domain. Then, the 3-D full-field ultrasonic data is Fourier transformed and the ultrasonic frequency spectra are analyzed to determine the dominant frequency that is sensitive to the disbond defects. Continuous wavelet transform (CWT) based on fast Fourier transform (FFT) is implemented as a single-frequency bandpass filter to filter the full-field ultrasonic data in the 3-D space-time domain at the selected dominant frequency. The LUIS has shown the ability to detect the disbond with diameters of 11 mm and 23 mm which match to the pre-determined disbond sizes well. For future research, a robust signal processing algorithm and a model-based matched filter will be investigated to make the detection process autonomous and improve detectability

  16. Identification of damage in plates using full-field measurement with a continuously scanning laser Doppler vibrometer system

    Science.gov (United States)

    Chen, Da-Ming; Xu, Y. F.; Zhu, W. D.

    2018-05-01

    An effective and reliable damage identification method for plates with a continuously scanning laser Doppler vibrometer (CSLDV) system is proposed. A new constant-speed scan algorithm is proposed to create a two-dimensional (2D) scan trajectory and automatically scan a whole plate surface. Full-field measurement of the plate can be achieved by applying the algorithm to the CSLDV system. Based on the new scan algorithm, the demodulation method is extended from one dimension for beams to two dimensions for plates to obtain a full-field operating deflection shape (ODS) of the plate from velocity response measured by the CSLDV system. The full-field ODS of an associated undamaged plate is obtained by using polynomials with proper orders to fit the corresponding full-field ODS from the demodulation method. A curvature damage index (CDI) using differences between curvatures of ODSs (CODSs) associated with ODSs that are obtained by the demodulation method and the polynomial fit is proposed to identify damage. An auxiliary CDI obtained by averaging CDIs at different excitation frequencies is defined to further assist damage identification. An experiment of an aluminum plate with damage in the form of 10.5% thickness reduction in a damage area of 0.86% of the whole scan area is conducted to investigate the proposed method. Six frequencies close to natural frequencies of the plate and one randomly selected frequency are used as sinusoidal excitation frequencies. Two 2D scan trajectories, i.e., a horizontally moving 2D scan trajectory and a vertically moving 2D scan trajectory, are used to obtain ODSs, CODSs, and CDIs of the plate. The damage is successfully identified near areas with consistently high values of CDIs at different excitation frequencies along the two 2D scan trajectories; the damage area is also identified by auxiliary CDIs.

  17. Full-field vibration measurements of the violin using digital stroboscopic holographic interferometry and electromagnetic stimulation of the strings

    Science.gov (United States)

    Keersmaekers, Lissa; Keustermans, William; De Greef, Daniël; Dirckx, Joris J. J.

    2016-06-01

    We developed a setup in which the strings of the violin are driven electromagnetically, and the resulting vibration of the instrument is measured with digital stroboscopic holography. A 250mW single mode green laser beam is chopped using an acousto-optic modulator, generating illumination pulses of 2% of the vibration period. The phase of the illumination pulse is controlled by a programmable function generator so that digital holograms can be recorded on a number of subsequent time positions within the vibration phase. From these recordings, the out of plane motion as a function of time is reconstructed in full field. We show results of full-field vibration amplitude and vibration phase maps, and time resolved full-field deformations of the violin back plane. Time resolved measurements show in detail how the deformation of the violin plane changes as a function of time at different frequencies. We found very different behavior under acoustic stimulation of the instrument and when using electromagnetic stimulation of a string. The aim of the work it to gather data which can be used in power flow calculations to study how the energy of the strings is conducted to the body of the violin and eventually is radiated as sound.

  18. Full-field vibration measurements of the violin using digital stroboscopic holographic interferometry and electromagnetic stimulation of the strings

    International Nuclear Information System (INIS)

    Keersmaekers, Lissa; Keustermans, William; De Greef, Daniël; Dirckx, Joris J. J.

    2016-01-01

    We developed a setup in which the strings of the violin are driven electromagnetically, and the resulting vibration of the instrument is measured with digital stroboscopic holography. A 250 mW single mode green laser beam is chopped using an acousto-optic modulator, generating illumination pulses of 2% of the vibration period. The phase of the illumination pulse is controlled by a programmable function generator so that digital holograms can be recorded on a number of subsequent time positions within the vibration phase. From these recordings, the out of plane motion as a function of time is reconstructed in full field. We show results of full-field vibration amplitude and vibration phase maps, and time resolved full-field deformations of the violin back plane. Time resolved measurements show in detail how the deformation of the violin plane changes as a function of time at different frequencies. We found very different behavior under acoustic stimulation of the instrument and when using electromagnetic stimulation of a string. The aim of the work it to gather data which can be used in power flow calculations to study how the energy of the strings is conducted to the body of the violin and eventually is radiated as sound.

  19. Full-field vibration measurements of the violin using digital stroboscopic holographic interferometry and electromagnetic stimulation of the strings

    Energy Technology Data Exchange (ETDEWEB)

    Keersmaekers, Lissa; Keustermans, William, E-mail: william.keustermans@uantwerpen.be; De Greef, Daniël; Dirckx, Joris J. J. [University of Antwerp, Laboratory of Biophysics and Biomedical Physics, Groenenborgerlaan 171, 2020 Antwerp (Belgium)

    2016-06-28

    We developed a setup in which the strings of the violin are driven electromagnetically, and the resulting vibration of the instrument is measured with digital stroboscopic holography. A 250 mW single mode green laser beam is chopped using an acousto-optic modulator, generating illumination pulses of 2% of the vibration period. The phase of the illumination pulse is controlled by a programmable function generator so that digital holograms can be recorded on a number of subsequent time positions within the vibration phase. From these recordings, the out of plane motion as a function of time is reconstructed in full field. We show results of full-field vibration amplitude and vibration phase maps, and time resolved full-field deformations of the violin back plane. Time resolved measurements show in detail how the deformation of the violin plane changes as a function of time at different frequencies. We found very different behavior under acoustic stimulation of the instrument and when using electromagnetic stimulation of a string. The aim of the work it to gather data which can be used in power flow calculations to study how the energy of the strings is conducted to the body of the violin and eventually is radiated as sound.

  20. Panel Session

    DEFF Research Database (Denmark)

    Bertelsen, Olav Wedege

    2004-01-01

    In this panel session, four researchers will discuss the role of a theoretical foundation, in particular AT, in the design of information technology based artefacts. The general discussion will take of from a specific examination of the ActAD approach.......In this panel session, four researchers will discuss the role of a theoretical foundation, in particular AT, in the design of information technology based artefacts. The general discussion will take of from a specific examination of the ActAD approach....

  1. White-light full-field OCT resolution improvement by image sensor colour balance adjustment: numerical simulation

    International Nuclear Information System (INIS)

    Kalyanov, A L; Lychagov, V V; Ryabukho, V P; Smirnov, I V

    2012-01-01

    The possibility of improving white-light full-field optical coherence tomography (OCT) resolution by image sensor colour balance tuning is shown numerically. We calculated the full-width at half-maximum (FWHM) of a coherence pulse registered by a silicon colour image sensor under various colour balance settings. The calculations were made for both a halogen lamp and white LED sources. The results show that the interference pulse width can be reduced by the proper choice of colour balance coefficients. The reduction is up to 18%, as compared with a colour image sensor with regular settings, and up to 20%, as compared with a monochrome sensor. (paper)

  2. Enhancement of the resolution of full-field optical coherence tomography by using a colour image sensor

    Energy Technology Data Exchange (ETDEWEB)

    Kalyanov, A L; Lychagov, V V; Smirnov, I V; Ryabukho, V P [N.G. Chernyshevsky Saratov State University, Saratov (Russian Federation)

    2013-08-31

    The influence of white balance in a colour image detector on the resolution of a full-field optical coherence tomograph (FFOCT) is studied. The change in the interference pulse width depending on the white balance tuning is estimated in the cases of a thermal radiation source (incandescent lamp) and a white light emitting diode. It is shown that by tuning white balance of the detector in a certain range, the FFOCT resolution can be increased by 20 % as compared to the resolution, attained with the use of a monochrome detector. (optical coherence tomography)

  3. Enhancement of the resolution of full-field optical coherence tomography by using a colour image sensor

    International Nuclear Information System (INIS)

    Kalyanov, A L; Lychagov, V V; Smirnov, I V; Ryabukho, V P

    2013-01-01

    The influence of white balance in a colour image detector on the resolution of a full-field optical coherence tomograph (FFOCT) is studied. The change in the interference pulse width depending on the white balance tuning is estimated in the cases of a thermal radiation source (incandescent lamp) and a white light emitting diode. It is shown that by tuning white balance of the detector in a certain range, the FFOCT resolution can be increased by 20 % as compared to the resolution, attained with the use of a monochrome detector. (optical coherence tomography)

  4. Flat-port connectors

    KAUST Repository

    Alrashed, Mohammed

    2017-05-26

    Disclosed are various embodiments for connectors used with electronic devices, such as input and/or output ports to connect peripheral equipment or accessories. More specifically, various flat-port are provided that can be used in place of standard connectors including, but not limited to, audio jacks and Universal Serial Bus (USB) ports. The flat-port connectors are an alternate connection design to replace the traditional receptacle port (female-port), making the device more sealed creation more dust and water resistant. It is unique in the way of using the outer surfaces of the device for the electrical connection between the ports. Flat-port design can allow the manufacture of extremely thin devices by eliminating the side ports slots that take a lot of space and contribute to the increase thickness of the device. The flat-port receptacle improves the overall appearance of the device and makes it more resistant to dust and water.

  5. Flat-space singletons

    International Nuclear Information System (INIS)

    Fronsdal, C.

    1987-01-01

    Singletons exist, as particles and as local fields, only in 3+2 de Sitter space. Their kinematical properties make them natural candidates for constituents of massless fields, and perhaps for quarks. It is interesting to find out how to describe this type of compositeness in flat space. A theory of interacting singleton fields in de Sitter space is now available, and in this paper we study the flat-space limit of the Green's functions of that theory. The flat-space limit is an autonomous theory of Green's functions, but is not an operator field theory. The three-point function is calculated and its flat-space limit is found to reveal glimpses of a physical interpretation. Causal and spectral properties are in accord with the tenets of axiomatic field theory. The theory is a generalization of local field theory, in which photons appear as composite objects although the physical S matrix is the same as in conventional QED

  6. DIGITAL IMAGE CORRELATION FROM COMMERCIAL TO FOS SOFTWARE: A MATURE TECHNIQUE FOR FULL-FIELD DISPLACEMENT MEASUREMENTS

    Directory of Open Access Journals (Sweden)

    V. Belloni

    2018-05-01

    Full Text Available In the last few decades, there has been a growing interest in studying non-contact methods for full-field displacement and strain measurement. Among such techniques, Digital Image Correlation (DIC has received particular attention, thanks to its ability to provide these information by comparing digital images of a sample surface before and after deformation. The method is now commonly adopted in the field of civil, mechanical and aerospace engineering and different companies and some research groups implemented 2D and 3D DIC software. In this work a review on DIC software status is given at first. Moreover, a free and open source 2D DIC software is presented, named py2DIC and developed in Python at the Geodesy and Geomatics Division of DICEA of the University of Rome “La Sapienza”; its potentialities were evaluated by processing the images captured during tensile tests performed in the Structural Engineering Lab of the University of Rome “La Sapienza” and comparing them to those obtained using the commercial software Vic-2D developed by Correlated Solutions Inc, USA. The agreement of these results at one hundredth of millimetre level demonstrate the possibility to use this open source software as a valuable 2D DIC tool to measure full-field displacements on the investigated sample surface.

  7. Noninvasive, three-dimensional full-field body sensor for surface deformation monitoring of human body in vivo

    Science.gov (United States)

    Chen, Zhenning; Shao, Xinxing; He, Xiaoyuan; Wu, Jialin; Xu, Xiangyang; Zhang, Jinlin

    2017-09-01

    Noninvasive, three-dimensional (3-D), full-field surface deformation measurements of the human body are important for biomedical investigations. We proposed a 3-D noninvasive, full-field body sensor based on stereo digital image correlation (stereo-DIC) for surface deformation monitoring of the human body in vivo. First, by applying an improved water-transfer printing (WTP) technique to transfer optimized speckle patterns onto the skin, the body sensor was conveniently and harmlessly fabricated directly onto the human body. Then, stereo-DIC was used to achieve 3-D noncontact and noninvasive surface deformation measurements. The accuracy and efficiency of the proposed body sensor were verified and discussed by considering different complexions. Moreover, the fabrication of speckle patterns on human skin, which has always been considered a challenging problem, was shown to be feasible, effective, and harmless as a result of the improved WTP technique. An application of the proposed stereo-DIC-based body sensor was demonstrated by measuring the pulse wave velocity of human carotid artery.

  8. Noninvasive, three-dimensional full-field body sensor for surface deformation monitoring of human body in vivo.

    Science.gov (United States)

    Chen, Zhenning; Shao, Xinxing; He, Xiaoyuan; Wu, Jialin; Xu, Xiangyang; Zhang, Jinlin

    2017-09-01

    Noninvasive, three-dimensional (3-D), full-field surface deformation measurements of the human body are important for biomedical investigations. We proposed a 3-D noninvasive, full-field body sensor based on stereo digital image correlation (stereo-DIC) for surface deformation monitoring of the human body in vivo. First, by applying an improved water-transfer printing (WTP) technique to transfer optimized speckle patterns onto the skin, the body sensor was conveniently and harmlessly fabricated directly onto the human body. Then, stereo-DIC was used to achieve 3-D noncontact and noninvasive surface deformation measurements. The accuracy and efficiency of the proposed body sensor were verified and discussed by considering different complexions. Moreover, the fabrication of speckle patterns on human skin, which has always been considered a challenging problem, was shown to be feasible, effective, and harmless as a result of the improved WTP technique. An application of the proposed stereo-DIC-based body sensor was demonstrated by measuring the pulse wave velocity of human carotid artery. (2017) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE).

  9. Automated high resolution full-field spatial coherence tomography for quantitative phase imaging of human red blood cells

    Science.gov (United States)

    Singla, Neeru; Dubey, Kavita; Srivastava, Vishal; Ahmad, Azeem; Mehta, D. S.

    2018-02-01

    We developed an automated high-resolution full-field spatial coherence tomography (FF-SCT) microscope for quantitative phase imaging that is based on the spatial, rather than the temporal, coherence gating. The Red and Green color laser light was used for finding the quantitative phase images of unstained human red blood cells (RBCs). This study uses morphological parameters of unstained RBCs phase images to distinguish between normal and infected cells. We recorded the single interferogram by a FF-SCT microscope for red and green color wavelength and average the two phase images to further reduced the noise artifacts. In order to characterize anemia infected from normal cells different morphological features were extracted and these features were used to train machine learning ensemble model to classify RBCs with high accuracy.

  10. Image stack alignment in full-field X-ray absorption spectroscopy using SIFT_PyOCL.

    Science.gov (United States)

    Paleo, Pierre; Pouyet, Emeline; Kieffer, Jérôme

    2014-03-01

    Full-field X-ray absorption spectroscopy experiments allow the acquisition of millions of spectra within minutes. However, the construction of the hyperspectral image requires an image alignment procedure with sub-pixel precision. While the image correlation algorithm has originally been used for image re-alignment using translations, the Scale Invariant Feature Transform (SIFT) algorithm (which is by design robust versus rotation, illumination change, translation and scaling) presents an additional advantage: the alignment can be limited to a region of interest of any arbitrary shape. In this context, a Python module, named SIFT_PyOCL, has been developed. It implements a parallel version of the SIFT algorithm in OpenCL, providing high-speed image registration and alignment both on processors and graphics cards. The performance of the algorithm allows online processing of large datasets.

  11. Feasibility of full-field optical coherence microscopy in ultra-structural imaging of human colon tissues

    Energy Technology Data Exchange (ETDEWEB)

    Choi, Eun Seo [Chosun University, Gwangju (Korea, Republic of); Choi, Woo June; Ryu, Seon Young; Lee, Byeong Ha [Gwangju Institute of Science and Technology, Gwangju (Korea, Republic of); Lee, Jae Hyuk; Bom, Hee Seung; Lee, Byeong Il [Chonnam National University Hospital, Gwangju (Korea, Republic of)

    2010-06-15

    We demonstrated the imaging feasibility of full-field optical coherence microscopy (FF-OCM) in pathological diagnosis of human colon tissues. FF-OCM images with high transverse resolution were obtained at different depths of the samples without any dye staining or physical slicing, and detailed microstructures of human colon tissues were visualized. Morphological differences in normal tissues, cancer tissues, and tissues under transition were observed and matched with results seen in conventional optical microscope images. The optical biopsy based on FF-OCM could overcome the limitations on the number of physical cuttings of tissues and could perform high-throughput mass diagnosis of diseased tissues. The proved utility of FF-OCM as a comprehensive and efficient imaging modality of human tissues showed it to be a good alternative to conventional biopsy.

  12. Feasibility of full-field optical coherence microscopy in ultra-structural imaging of human colon tissues

    International Nuclear Information System (INIS)

    Choi, Eun Seo; Choi, Woo June; Ryu, Seon Young; Lee, Byeong Ha; Lee, Jae Hyuk; Bom, Hee Seung; Lee, Byeong Il

    2010-01-01

    We demonstrated the imaging feasibility of full-field optical coherence microscopy (FF-OCM) in pathological diagnosis of human colon tissues. FF-OCM images with high transverse resolution were obtained at different depths of the samples without any dye staining or physical slicing, and detailed microstructures of human colon tissues were visualized. Morphological differences in normal tissues, cancer tissues, and tissues under transition were observed and matched with results seen in conventional optical microscope images. The optical biopsy based on FF-OCM could overcome the limitations on the number of physical cuttings of tissues and could perform high-throughput mass diagnosis of diseased tissues. The proved utility of FF-OCM as a comprehensive and efficient imaging modality of human tissues showed it to be a good alternative to conventional biopsy.

  13. High-dynamic-range microscope imaging based on exposure bracketing in full-field optical coherence tomography.

    Science.gov (United States)

    Leong-Hoi, Audrey; Montgomery, Paul C; Serio, Bruno; Twardowski, Patrice; Uhring, Wilfried

    2016-04-01

    By applying the proposed high-dynamic-range (HDR) technique based on exposure bracketing, we demonstrate a meaningful reduction in the spatial noise in image frames acquired with a CCD camera so as to improve the fringe contrast in full-field optical coherence tomography (FF-OCT). This new signal processing method thus allows improved probing within transparent or semitransparent samples. The proposed method is demonstrated on 3 μm thick transparent polymer films of Mylar, which, due to their transparency, produce low contrast fringe patterns in white-light interference microscopy. High-resolution tomographic analysis is performed using the technique. After performing appropriate signal processing, resulting XZ sections are observed. Submicrometer-sized defects can be lost in the noise that is present in the CCD images. With the proposed method, we show that by increasing the signal-to-noise ratio of the images, submicrometer-sized defect structures can thus be detected.

  14. Achieving sub-millimetre precision with a solid-state full-field heterodyning range imaging camera

    Science.gov (United States)

    Dorrington, A. A.; Cree, M. J.; Payne, A. D.; Conroy, R. M.; Carnegie, D. A.

    2007-09-01

    We have developed a full-field solid-state range imaging system capable of capturing range and intensity data simultaneously for every pixel in a scene with sub-millimetre range precision. The system is based on indirect time-of-flight measurements by heterodyning intensity-modulated illumination with a gain modulation intensified digital video camera. Sub-millimetre precision to beyond 5 m and 2 mm precision out to 12 m has been achieved. In this paper, we describe the new sub-millimetre class range imaging system in detail, and review the important aspects that have been instrumental in achieving high precision ranging. We also present the results of performance characterization experiments and a method of resolving the range ambiguity problem associated with homodyne and heterodyne ranging systems.

  15. 3D palmprint and hand imaging system based on full-field composite color sinusoidal fringe projection technique.

    Science.gov (United States)

    Zhang, Zonghua; Huang, Shujun; Xu, Yongjia; Chen, Chao; Zhao, Yan; Gao, Nan; Xiao, Yanjun

    2013-09-01

    Palmprint and hand shape, as two kinds of important biometric characteristics, have been widely studied and applied to human identity recognition. The existing research is based mainly on 2D images, which lose the third-dimensional information. The biological features extracted from 2D images are distorted by pressure and rolling, so the subsequent feature matching and recognition are inaccurate. This paper presents a method to acquire accurate 3D shapes of palmprint and hand by projecting full-field composite color sinusoidal fringe patterns and the corresponding color texture information. A 3D imaging system is designed to capture and process the full-field composite color fringe patterns on hand surface. Composite color fringe patterns having the optimum three fringe numbers are generated by software and projected onto the surface of human hand by a digital light processing projector. From another viewpoint, a color CCD camera captures the deformed fringe patterns and saves them for postprocessing. After compensating for the cross talk and chromatic aberration between color channels, three fringe patterns are extracted from three color channels of a captured composite color image. Wrapped phase information can be calculated from the sinusoidal fringe patterns with high precision. At the same time, the absolute phase of each pixel is determined by the optimum three-fringe selection method. After building up the relationship between absolute phase map and 3D shape data, the 3D palmprint and hand are obtained. Color texture information can be directly captured or demodulated from the captured composite fringe pattern images. Experimental results show that the proposed method and system can yield accurate 3D shape and color texture information of the palmprint and hand shape.

  16. Rocky Flats Compliance Program

    International Nuclear Information System (INIS)

    1994-02-01

    The Department of Energy (DOE) established the Office of Technology Development (EM-50) (OTD) as an element of Environmental Restoration and Waste Management (EM) in November 1989. The primary objective of the Office of Technology Development, Rocky Flats Compliance Program (RFCP), is to develop altemative treatment technologies for mixed low-level waste (wastes containing both hazardous and radioactive components) to use in bringing the Rocky Flats Plant (RFP) into compliance with Federal and state regulations and agreements. Approximately 48,000 cubic feet of untreated low-level mixed waste, for which treatment has not been specified, are stored at the RFP. The cleanup of the Rocky Flats site is driven by agreements between DOE, the Environmental Protection Agency (EPA), and the Colorado Department of Health (CDH). Under these agreements, a Comprehensive Treatment and Management Plan (CTMP) was drafted to outline the mechanisms by which RFP will achieve compliance with the regulations and agreements. This document describes DOE's strategy to treat low-level mixed waste to meet Land Disposal Restrictions and sets specific milestones related to the regulatory aspects of technology development. These milestones detail schedules for the development of technologies to treat all of the mixed wastes at the RFP. Under the Federal Facilities Compliance Act (FFCA), the CTMP has been incorporated into Rocky Flats Plant Conceptual Site Treatment Plan (CSTP). The CSTP will become the Rocky Flats Plant site Treatment Plan in 1995 and will supersede the CTMP

  17. Lipid Panel

    Science.gov (United States)

    ... A routine cardiac risk assessment typically includes a fasting lipid panel. Beyond that, research continues into the usefulness of other non-traditional markers of cardiac risk, such as Lp-PLA 2 . A health practitioner may choose to evaluate one or more ...

  18. Flat-screen detector systems in skeletal radiology

    International Nuclear Information System (INIS)

    Grampp, S.; Czerny, C.; Krestan, C.; Henk, C.; Heiner, L.; Imhof, H.

    2003-01-01

    Implementation of flat-panel detectors and digital integration of the technique instead of the use of conventional radiographs leads to a shortening of the work process. With flat-panel technology the image production process is shortened by more than 30%. Major advantages in the implementation of integrated RIS, PACS and flat-panel detector system are increases in quality because most mistakes in picture labeling can be avoided, easier handling without the need for cassettes, and the possibility of image post-processing. The diagnostic quality of the images in the field of musculoskeletal radiology is, in comparison to conventional radiographs, at least adequate and in most cases markedly improved with a marked reduction in radiation exposure of around 30-50%. With respect to the numerous advantages of the digital techniques and especially flat-panel technology there is a very high likelihood that conventional radiographs will be substituted in the coming years, even though the cost of the new technology is currently significantly higher compared to conventional systems. (orig.) [de

  19. Fire-induced reradiation underneath photovoltaic arrays on flat roofs

    DEFF Research Database (Denmark)

    Kristensen, Jens Steemann; Merci, Bart; Jomaas, Grunde

    2018-01-01

    The impact of the reflection of fire-induced heat from a gas burner was studied experimentally to gain knowledge on the interaction between photovoltaic (PV) panels and a fire on flat roofs. The heat flux was measured in a total of eight points at the same level as the top of the gas burner. The ...

  20. Blind identification of full-field vibration modes from video measurements with phase-based video motion magnification

    Science.gov (United States)

    Yang, Yongchao; Dorn, Charles; Mancini, Tyler; Talken, Zachary; Kenyon, Garrett; Farrar, Charles; Mascareñas, David

    2017-02-01

    user supervision and calibration. First a multi-scale image processing method is applied on the frames of the video of a vibrating structure to extract the local pixel phases that encode local structural vibration, establishing a full-field spatiotemporal motion matrix. Then a high-spatial dimensional, yet low-modal-dimensional, over-complete model is used to represent the extracted full-field motion matrix using modal superposition, which is physically connected and manipulated by a family of unsupervised learning models and techniques, respectively. Thus, the proposed method is able to blindly extract modal frequencies, damping ratios, and full-field (as many points as the pixel number of the video frame) mode shapes from line of sight video measurements of the structure. The method is validated by laboratory experiments on a bench-scale building structure and a cantilever beam. Its ability for output (video measurements)-only identification and visualization of the weakly-excited mode is demonstrated and several issues with its implementation are discussed.

  1. Breast imaging using an amorphous silicon-based full-field digital mammographic system: stability of a clinical prototype.

    Science.gov (United States)

    Vedantham, S; Karellas, A; Suryanarayanan, S; D'Orsi, C J; Hendrick, R E

    2000-11-01

    An amorphous silicon-based full-breast imager for digital mammography was evaluated for detector stability over a period of 1 year. This imager uses a structured CsI:TI scintillator coupled to an amorphous silicon layer with a 100-micron pixel pitch and read out by special purpose electronics. The stability of the system was characterized using the following quantifiable metrics: conversion factor (mean number of electrons generated per incident x-ray), presampling modulation transfer function (MTF), detector linearity and sensitivity, detector signal-to-noise ratio (SNR), and American College of Radiology (ACR) accreditation phantom scores. Qualitative metrics such as flat field uniformity, geometric distortion, and Society of Motion Picture and Television Engineers (SMPTE) test pattern image quality were also used to study the stability of the system. Observations made over this 1-year period indicated that the maximum variation from the average of the measurements were less than 0.5% for conversion factor, 3% for presampling MTF over all spatial frequencies, 5% for signal response, linearity and sensitivity, 12% for SNR over seven locations for all 3 target-filter combinations, and 0% for ACR accreditation phantom scores. ACR mammographic accreditation phantom images indicated the ability to resolve 5 fibers, 4 speck groups, and 5 masses at a mean glandular dose of 1.23 mGy. The SMPTE pattern image quality test for the display monitors used for image viewing indicated ability to discern all contrast steps and ability to distinguish line-pair images at the center and corners of the image. No bleeding effects were observed in the image. Flat field uniformity for all 3 target-filter combinations displayed no artifacts such as gridlines, bad detector rows or columns, horizontal or vertical streaks, or bad pixels. Wire mesh screen images indicated uniform resolution and no geometric distortion.

  2. Multiple-Panel Cylindrical Solar Concentrator

    Science.gov (United States)

    Brown, E. M.

    1983-01-01

    Trough composed of many panels concentrates Sun's energy on solar cells, even when trough is not pointed directly at Sun. Tolerates deviation as great as 5 degrees from direction of sun. For terrestrial applications, multiple-flat-plate design offers potential cost reduction and ease of fabrication.

  3. Foil Panel Mirrors for Nonimaging Applications

    Science.gov (United States)

    Kuyper, D. J.; Castillo, A. A.

    1984-01-01

    Large durable, lightweight mirrors made by bonding thick aluminum foil to honeycomb panels or other rigid, flat backings. Mirrors suitable for use as infrared shields, telescope doors, solar-furnance doors, advertising displays, or other reflectors that require low thermal emissivity and high specularity but do not require precise surface figure necessary for imaging.

  4. Human Visual Performance and Flat Panel Display Image Quality

    Science.gov (United States)

    1980-07-01

    visible light energy can be described in electro- magnetic energy space as that portion of the electromagnetic wavelength (or frequency) domain to...temporal frequency domain much as one analyzes spatial information in the spatial frequency domain. As the content of a complex but periodic sound ...briefly with the more intepretive aspects of information display, those pertaining to information encoding and the design problems and parame- ters

  5. CMOS Flat-Panel CBCT for Dental Imaging

    International Nuclear Information System (INIS)

    Youn, Han Bean; Cho, Min Kook; Kim, Jee Young; Lee, Hyun Ji; Cho, Bong Hye; Heo, Sung Kyn

    2009-01-01

    Computed tomography (CT) has become one of the most frequently used imaging modalities for the preoperative evaluation of the jaw for dental implants. Sometimes dental Implant surgery needs histologic information of the regeneration of bone structure However conventional dental CT cannot serve these information because of its resolution limit. Hence we suggest dental CT which has micro scale resolution with high magnification factor. In these regards, We investigated micro dental CT with optimal magnification factor about our hardware system and evaluated along the 2D and 3D performance experimentally

  6. Flat-port connectors

    KAUST Repository

    Alrashed, Mohammed

    2017-01-01

    and water resistant. It is unique in the way of using the outer surfaces of the device for the electrical connection between the ports. Flat-port design can allow the manufacture of extremely thin devices by eliminating the side ports slots that take a lot

  7. Piecewise flat gravitational waves

    NARCIS (Netherlands)

    van de Meent, M.

    2011-01-01

    We examine the continuum limit of the piecewise flat locally finite gravity model introduced by ’t Hooft. In the linear weak field limit, we find the energy–momentum tensor and metric perturbation of an arbitrary configuration of defects. The energy–momentum turns out to be restricted to satisfy

  8. Flat out and bluesome

    OpenAIRE

    Wilson, Mark; Snaebjornsdottir, Bryndis; Byatt, Lucy

    2008-01-01

    ‘Nanoq: flat out and bluesome’ is the story of polar bears, the largest land predators on earth, and their journey from the arctic wilderness to the museums and stately homes of the UK. The work documents the histories of each of these bears, the legacies of the hunters who shot them and the skills and expertise of the taxidermists who stuffed them.

  9. Panel discussion

    International Nuclear Information System (INIS)

    Anon.

    1980-01-01

    The panel discussion at the 10th Allianz Forum on 'Technology and Insurance' dealt with the following topics: New technologies: energy conversion (coal, petroleum, natural gas, nuclear energy, solar energy); infrastructure (transport, data processing); basic products (metallic materials, chemical products, pharmaceutical products); integrated products (microprocessors, production line machines) as well as new risks: political; general economic (financing, market structure); insurance-related, dangers to persons and property; reduction of risks. (orig.) [de

  10. Simultaneous topography and tomography of latent fingerprints using full-field swept-source optical coherence tomography

    Science.gov (United States)

    Dubey, Satish Kumar; Singh Mehta, Dalip; Anand, Arun; Shakher, Chandra

    2008-01-01

    We demonstrate simultaneous topography and tomography of latent fingerprints using full-field swept-source optical coherence tomography (OCT). The swept-source OCT system comprises a superluminescent diode (SLD) as broad-band light source, an acousto-optic tunable filter (AOTF) as frequency tuning device, and a compact, nearly common-path interferometer. Both the amplitude and the phase map of the interference fringe signal are reconstructed. Optical sectioning of the latent fingerprint sample is obtained by selective Fourier filtering and the topography is retrieved from the phase map. Interferometry, selective filtering, low coherence and hence better resolution are some of the advantages of the proposed system over the conventional fingerprint detection techniques. The present technique is non-invasive in nature and does not require any physical or chemical processing. Therefore, the quality of the sample does not alter and hence the same fingerprint can be used for other types of forensic test. Exploitation of low-coherence interferometry for fingerprint detection itself provides an edge over other existing techniques as fingerprints can even be lifted from low-reflecting surfaces. The proposed system is very economical and compact.

  11. Studies Comparing Screen-Film Mammography and Full-Field Digital Mammography in Breast Cancer Screening: Updated Review

    International Nuclear Information System (INIS)

    Skaane, P.

    2009-01-01

    Full-field digital mammography (FFDM) has several potential benefits as compared with screen-film mammography (SFM) in mammography screening. Digital technology also opens for implementation of advanced applications, including computer-aided detection (CAD) and tomosynthesis. Phantom studies and experimental clinical studies have shown that FFDM is equal or slightly superior to SFM for detection and characterization of mammographic abnormalities. Despite obvious advantages, the conversion to digital mammography has been slower than anticipated, and not only due to higher costs. Until very recently, some countries did not even permit the use of digital mammography in breast cancer screening. The reason for this reluctant attitude was concern about lower spatial resolution and about using soft-copy reading. Furthermore, there was a lack of data supporting improved diagnostic accuracy using FFDM in a screening setting, since two pioneer trials both showed nonsignificantly lower cancer detection rate at FFDM. The 10 studies comparing FFDM and SFM in mammography screening published so far have shown divergent and rather conflicting results. Nevertheless, there is a rapid conversion to digital mammography in breast cancer screening in many western countries. The aim of this article is to give an updated review of these studies, discuss the conflicting findings, and draw some conclusions from the results

  12. Comparing the visualization of microcalcifications with direct magnification in digital full-field mammography vs. film-screen mammography

    International Nuclear Information System (INIS)

    Diekmann, F.; Diekmann, S.; Rogalla, P.; Hamm, B.; Bick, U.; Blohmer, J.U.; Winzer, K.J.

    2002-01-01

    Purpose: To evaluate the conspicuity of microcalcifications in magnified mammographic views of preparations obtained with full field digital mammography (FFDM), film-screen mammography (FSM), and the DIMA technique. Material and Methods: Twelve preparations were examined by FFDM and FSM using 1.8 x magnification and DIMA using 7 x magnification. Parameter settings were identical for all three techniques. The number of visible microcalcifications was then determined for each modality by three radiologists. As far as possible, all preparations were X-rayed at 22 kV and 10 mAS. Results: Altogether 9705 calcifications were counted (DIMA: 1609/1542/1534; FFDM: 1020/753/881; FSM: 901/643/822). The total number of microcalcifications identified with the DIMA technique was 4685 as compared to 2654 with FFDM and 2366 with FSM. The calcifications counted with FFDM and FSM thus corresponded to 56.6% and 50.5%, respectively, of those identified with DIMA. The differences between the groups were statistically significant (F-Test, p [de

  13. Comparative analysis of full-field digital mammography and magnetic resonance imaging in the diagnosis of malignant breast tumor

    International Nuclear Information System (INIS)

    Xu Chuan; Meng Xiaochun; Kong Qingcong; Wang Xiaohong; Zhang Jiansheng

    2007-01-01

    Objective: To retrospectively compare the efficacy of full-field digital mammography (FFDM) and magnetic resonance imaging (MRI) in the diagnosis of mammary cancer. Methods: 93 cases suspected mammary lesions both received FFDM and MRI examinations. Compared with pathology, we analyzed the imaging features of mammary cancer in these two methods and investigated the capability of these two methods in mammary cancer diagnosis. Results: The sensitivity, specificity, predictive value of positive cases, predictive value of negative cases and accuracy of FFDM in mammary cancer were 84.48%, 80.00%, 87.50%, 75.68% and 82.80% respectively; the detection rate for multi-focus was 55.56%. And the detection rate for microcalcifications in FFDM examination (29/69) was much higher than in MR/(7/69). The sensitivity, specificity, predictive value of positive cases, predictive value of negative cases and accuracy of MR/in mammary cancer diagnosis were 94.82%, 97.14%, 98.21%, 91.89% and 95.69%, respectively; the detection rate for multi-focus was 83.33%. The spiculate margin, ringed enhancement of the peripheral part of tumor and the fast-in-and-fast-out type of the time-signal intensity curve were the diagnostic signs of breast cancer. Conclusion: FFDM was sensitive for breast microcalcifications and could be feasible for breast cancer screening. MR/had a high sensitivity and specificity for breast cancer diagnosis, which could be effective for pre-operation estimation. (authors)

  14. A simple method to achieve full-field and real-scale reconstruction using a movable stereo rig

    Science.gov (United States)

    Gu, Feifei; Zhao, Hong; Song, Zhan; Tang, Suming

    2018-06-01

    This paper introduces a simple method to achieve full-field and real-scale reconstruction using a movable binocular vision system (MBVS). The MBVS is composed of two cameras, one is called the tracking camera, and the other is called the working camera. The tracking camera is used for tracking the positions of the MBVS and the working camera is used for the 3D reconstruction task. The MBVS has several advantages compared with a single moving camera or multi-camera networks. Firstly, the MBVS could recover the real-scale-depth-information from the captured image sequences without using auxiliary objects whose geometry or motion should be precisely known. Secondly, the removability of the system could guarantee appropriate baselines to supply more robust point correspondences. Additionally, using one camera could avoid the drawback which exists in multi-camera networks, that the variability of a cameras’ parameters and performance could significantly affect the accuracy and robustness of the feature extraction and stereo matching methods. The proposed framework consists of local reconstruction and initial pose estimation of the MBVS based on transferable features, followed by overall optimization and accurate integration of multi-view 3D reconstruction data. The whole process requires no information other than the input images. The framework has been verified with real data, and very good results have been obtained.

  15. Comparing search patterns in digital breast tomosynthesis and full-field digital mammography: an eye tracking study.

    Science.gov (United States)

    Aizenman, Avi; Drew, Trafton; Ehinger, Krista A; Georgian-Smith, Dianne; Wolfe, Jeremy M

    2017-10-01

    As a promising imaging modality, digital breast tomosynthesis (DBT) leads to better diagnostic performance than traditional full-field digital mammograms (FFDM) alone. DBT allows different planes of the breast to be visualized, reducing occlusion from overlapping tissue. Although DBT is gaining popularity, best practices for search strategies in this medium are unclear. Eye tracking allowed us to describe search patterns adopted by radiologists searching DBT and FFDM images. Eleven radiologists examined eight DBT and FFDM cases. Observers marked suspicious masses with mouse clicks. Eye position was recorded at 1000 Hz and was coregistered with slice/depth plane as the radiologist scrolled through the DBT images, allowing a 3-D representation of eye position. Hit rate for masses was higher for tomography cases than 2-D cases and DBT led to lower false positive rates. However, search duration was much longer for DBT cases than FFDM. DBT was associated with longer fixations but similar saccadic amplitude compared with FFDM. When comparing radiologists' eye movements to a previous study, which tracked eye movements as radiologists read chest CT, we found DBT viewers did not align with previously identified "driller" or "scanner" strategies, although their search strategy most closely aligns with a type of vigorous drilling strategy.

  16. Multi-kernel deconvolution for contrast improvement in a full field imaging system with engineered PSFs using conical diffraction

    Science.gov (United States)

    Enguita, Jose M.; Álvarez, Ignacio; González, Rafael C.; Cancelas, Jose A.

    2018-01-01

    The problem of restoration of a high-resolution image from several degraded versions of the same scene (deconvolution) has been receiving attention in the last years in fields such as optics and computer vision. Deconvolution methods are usually based on sets of images taken with small (sub-pixel) displacements or slightly different focus. Techniques based on sets of images obtained with different point-spread-functions (PSFs) engineered by an optical system are less popular and mostly restricted to microscopic systems, where a spot of light is projected onto the sample under investigation, which is then scanned point-by-point. In this paper, we use the effect of conical diffraction to shape the PSFs in a full-field macroscopic imaging system. We describe a series of simulations and real experiments that help to evaluate the possibilities of the system, showing the enhancement in image contrast even at frequencies that are strongly filtered by the lens transfer function or when sampling near the Nyquist frequency. Although results are preliminary and there is room to optimize the prototype, the idea shows promise to overcome the limitations of the image sensor technology in many fields, such as forensics, medical, satellite, or scientific imaging.

  17. Computer-aided detection of masses in full-field digital mammography using screen-film mammograms for training

    International Nuclear Information System (INIS)

    Kallenberg, Michiel; Karssemeijer, Nico

    2008-01-01

    It would be of great value when available databases of screen-film mammography (SFM) images can be used to train full-field digital mammography (FFDM) computer-aided detection (CAD) systems, as compilation of new databases is costly. In this paper, we investigate this possibility. Firstly, we develop a method that converts an FFDM image into an SFM-like representation. In this conversion method, we establish a relation between exposure and optical density by simulation of an automatic exposure control unit. Secondly, we investigate the effects of using the SFM images as training samples compared to training with FFDM images. Our FFDM database consisted of 266 cases, of which 102 were biopsy-proven malignant masses and 164 normals. The images were acquired with systems of two different manufacturers. We found that, when we trained our FFDM CAD system with a small number of images, training with FFDM images, using a five-fold crossvalidation procedure, outperformed training with SFM images. However, when the full SFM database, consisting of 348 abnormal cases (including 204 priors) and 810 normal cases, was used for training, SFM training outperformed FFDMA training. These results show that an existing CAD system for detection of masses in SFM can be used for FFDM images without retraining.

  18. Defect Localization Capabilities of a Global Detection Scheme: Spatial Pattern Recognition Using Full-field Vibration Test Data in Plates

    Science.gov (United States)

    Saleeb, A. F.; Prabhu, M.; Arnold, S. M. (Technical Monitor)

    2002-01-01

    Recently, a conceptually simple approach, based on the notion of defect energy in material space has been developed and extensively studied (from the theoretical and computational standpoints). The present study focuses on its evaluation from the viewpoint of damage localization capabilities in case of two-dimensional plates; i.e., spatial pattern recognition on surfaces. To this end, two different experimental modal test results are utilized; i.e., (1) conventional modal testing using (white noise) excitation and accelerometer-type sensors and (2) pattern recognition using Electronic speckle pattern interferometry (ESPI), a full field method capable of analyzing the mechanical vibration of complex structures. Unlike the conventional modal testing technique (using contacting accelerometers), these emerging ESPI technologies operate in a non-contacting mode, can be used even under hazardous conditions with minimal or no presence of noise and can simultaneously provide measurements for both translations and rotations. Results obtained have clearly demonstrated the robustness and versatility of the global NDE scheme developed. The vectorial character of the indices used, which enabled the extraction of distinct patterns for localizing damages proved very useful. In the context of the targeted pattern recognition paradigm, two algorithms were developed for the interrogation of test measurements; i.e., intensity contour maps for the damaged index, and the associated defect energy vector field plots.

  19. Imaging cells and sub-cellular structures with ultrahigh resolution full-field X-ray microscopy.

    Science.gov (United States)

    Chien, C C; Tseng, P Y; Chen, H H; Hua, T E; Chen, S T; Chen, Y Y; Leng, W H; Wang, C H; Hwu, Y; Yin, G C; Liang, K S; Chen, F R; Chu, Y S; Yeh, H I; Yang, Y C; Yang, C S; Zhang, G L; Je, J H; Margaritondo, G

    2013-01-01

    Our experimental results demonstrate that full-field hard-X-ray microscopy is finally able to investigate the internal structure of cells in tissues. This result was made possible by three main factors: the use of a coherent (synchrotron) source of X-rays, the exploitation of contrast mechanisms based on the real part of the refractive index and the magnification provided by high-resolution Fresnel zone-plate objectives. We specifically obtained high-quality microradiographs of human and mouse cells with 29 nm Rayleigh spatial resolution and verified that tomographic reconstruction could be implemented with a final resolution level suitable for subcellular features. We also demonstrated that a phase retrieval method based on a wave propagation algorithm could yield good subcellular images starting from a series of defocused microradiographs. The concluding discussion compares cellular and subcellular hard-X-ray microradiology with other techniques and evaluates its potential impact on biomedical research. Copyright © 2012 Elsevier Inc. All rights reserved.

  20. Comparison of screen-film and full-field digital mammography in Japanese population-based screening

    International Nuclear Information System (INIS)

    Yamada, Takayuki; Saito, Mioko; Ishibashi, Tadashi

    2004-01-01

    The purpose of this study was to investigate how the greater contrast of full-field digital mammography (FFDM) affects the detection of suspicious lesions in Japanese population-based screening. Screen-film mammography (SFM) and FFDM were performed in 480 women aged 50 years or more. A set of mediolateral oblique views was obtained with each modality. All mammograms were independently double-read. The five-scale category assessment and type of finding using the Breast Imaging Reporting and Data System (BIRADS) nomenclature were given. Intraobserver variance, recall rates, and positive predictive value were calculated. The findings between the two modalities were discordant. κ-values for each reader were 0.619 and 0.385, respectively. Almost half of the microcalcifications were called with both modalities. The detection of masses was less concordant between the readers (27%). The masses were detected more frequently with FFDM (73%). Other findings were only detected with one modality. The recall rate was not significantly different (2.9% with SFM vs. 4.2% with FFDM; p=0.253). The positive predictive value was not significantly different (14% with SFM vs. 10% with FFDM; p=0.69), either. Two patients with breast cancer were detected with both modalities. Recall rates and positive predictive value were not significantly different between SFM and FFDM. Cancers were detected with both modalities. (author)

  1. Performance of computer-aided detection applied to full-field digital mammography in detection of breast cancers

    International Nuclear Information System (INIS)

    Sadaf, Arifa; Crystal, Pavel; Scaranelo, Anabel; Helbich, Thomas

    2011-01-01

    Objective: The aim of this retrospective study was to evaluate performance of computer-aided detection (CAD) with full-field digital mammography (FFDM) in detection of breast cancers. Materials and Methods: CAD was retrospectively applied to standard mammographic views of 127 cases with biopsy proven breast cancers detected with FFDM (Senographe 2000, GE Medical Systems). CAD sensitivity was assessed in total group of 127 cases and for subgroups based on breast density, mammographic lesion type, mammographic lesion size, histopathology and mode of presentation. Results: Overall CAD sensitivity was 91% (115 of 127 cases). There were no statistical differences (p > 0.1) in CAD detection of cancers in dense breasts 90% (53/59) versus non-dense breasts 91% (62/68). There was statistical difference (p 20 mm 97% (22/23). Conclusion: CAD applied to FFDM showed 100% sensitivity in identifying cancers manifesting as microcalcifications only and high sensitivity 86% (71/83) for other mammographic appearances of cancer. Sensitivity is influenced by lesion size. CAD in FFDM is an adjunct helping radiologist in early detection of breast cancers.

  2. Integrating single-point vibrometer and full-field electronic speckle pattern interferometer to evaluate a micro-speaker

    Science.gov (United States)

    Chang, Wen-Chi; Chen, Yu-Chi; Chien, Chih-Jen; Wang, An-Bang; Lee, Chih-Kung

    2011-04-01

    A testing system contains an advanced vibrometer/interferometer device (AVID) and a high-speed electronic speckle pattern interferometer (ESPI) was developed. AVID is a laser Doppler vibrometer that can be used to detect single-point linear and angular velocity with DC to 20 MHz bandwidth and with nanometer resolution. In swept frequency mode, frequency response from mHz to MHz of the structure of interest can be measured. The ESPI experimental setup can be used to measure full-field out-of-plane displacement. A 5-1 phase shifting method and a correlation algorithm were used to analyze the phase difference between the reference signal and the speckle signal scattered from the sample surface. In order to show the efficiency and effectiveness of AVID and ESPI, we designed a micro-speaker composed of a plate with fixed boundaries and two piezo-actuators attached to the sides of the plate. The AVID was used to measure the vibration of one of the piezo-actuators and the ESPI was adopted to measure the two-dimensional out-of-plane displacement of the plate. A microphone was used to measure the acoustic response created by the micro-speaker. Driving signal includes random signal, sinusoidal signal, amplitude modulated high-frequency carrier signal, etc. Angular response induced by amplitude modulated high-frequency carrier signal was found to be significantly narrower than the frequency responses created by other types of driving signals. The validity of our newly developed NDE system are detailed by comparing the relationship between the vibration signal of the micro-speaker and the acoustic field generated.

  3. Assessing tumor extent on contrast-enhanced spectral mammography versus full-field digital mammography and ultrasound.

    Science.gov (United States)

    Patel, Bhavika K; Garza, Sandra Alheli; Eversman, Sarah; Lopez-Alvarez, Yania; Kosiorek, Heidi; Pockaj, Barbara A

    To compare breast cancer size measurements on full-field digital mammography (FFDM), contrast-enhanced spectral mammography (CEDM), and ultrasound (US), with histologic tumor size used as the reference standard. Material and methods The HIPAA complaint, IRB approved study comprised 88 women with newly diagnosed breast cancer who underwent FFDM and CEDM;74 also had US. Breast density, histologic subtype, and maximum tumor measurements were recorded. Pearson correlation coefficients for FFDM, US, and CEDM vs histopathology were 0.598, 0.639, and 0.859, respectively (P<0.001). The following correlation coefficients were calculated for dense breasts (n=48): histopathology vs FFDM (0.555), US (0.633), and CEDM (0.843) (P<0.001); for nondense breasts (n=40), they were FFDM (0.618), US (0.512), and CEDM (0.885) (P<0.001). For size difference, the mean (SD) for histopathology vs FFDM, US, and CEDM was -1.3 (11.9) mm, -2.8 (11.1) mm, and 2.9 (9.5) mm, respectively. Limits of agreement were -24.8 to 22.0mm, -24.5 to 18.8mm, and -15.6 to 21.4mm, respectively. In patients with biopsy-proven malignancy, size measurements correlated well with histopathologic size, and were higher on CEDM than those for FFDM and US in patients with dense or nondense breasts. The added value of CEDM as a supplement to FFDM in determining tumor size, however, was greater in patients with dense breasts. CEDM may be a promising alternative preoperative measurement tool for breast cancer patients with dense breasts and/or limited access or contraindications to MRI. Copyright © 2017 Elsevier Inc. All rights reserved.

  4. Validation of full-field optical coherence tomography in distinguishing malignant and benign tissue in resected pancreatic cancer specimens.

    Directory of Open Access Journals (Sweden)

    Labrinus van Manen

    Full Text Available Pancreatic cancer is the fourth leading cause of cancer-related mortality in the United States. The minority of patients can undergo curative-intended surgical therapy due to progressive disease stage at time of diagnosis. Nonetheless, tumor involvement of surgical margins is seen in up to 70% of resections, being a strong negative prognostic factor. Real-time intraoperative imaging modalities may aid surgeons to obtain tumor-free resection margins. Full-field optical coherence tomography (FF-OCT is a promising diagnostic tool using high-resolution white-light interference microscopy without tissue processing. Therefore, we composed an atlas of FF-OCT images of malignant and benign pancreatic tissue, and investigated the accuracy with which the pathologists could distinguish these.One hundred FF-OCT images were collected from specimens of 29 patients who underwent pancreatic resection for various indications between 2014 and 2016. One experienced gastrointestinal pathologist and one pathologist in training scored independently the FF-OCT images as malignant or benign blinded to the final pathology conclusion. Results were compared to those obtained with standard hematoxylin and eosin (H&E slides.Overall, combined test characteristics of both pathologists showed a sensitivity of 72%, specificity of 74%, positive predictive value of 69%, negative predictive value of 79% and an overall accuracy of 73%. In the subset of pancreatic ductal adenocarcinoma patients, 97% of the FF-OCT images (n = 35 were interpreted as tumor by at least one pathologist. Moreover, normal pancreatic tissue was recognised in all cases by at least one pathologist. However, atrophy and fibrosis, serous cystadenoma and neuroendocrine tumors were more often wrongly scored, in 63%, 100% and 25% respectively.FF-OCT could distinguish normal pancreatic tissue from pathologic pancreatic tissue in both processed as non-processed specimens using architectural features. The accuracy in

  5. Full-Field Stress Determination Around Circular Discontinuity in a Tensile-Loaded Plate using x-displacements Only

    Science.gov (United States)

    Baek, Tae Hyun; Chung, Tae Jin; Panganiban, Henry

    The significant effects of stress raisers demand well-defined evaluation techniques to accurately determine the stress along the geometric boundary. A simple and accurate method for the determination of stress concentration around circular geometric discontinuity in a tensile-loaded plate is illustrated. The method is based on the least-squares technique, mapping functions, and a complex power series representation (Laurent series) of the stress functions for the calculation of tangential stress around the hole. Traction-free conditions were satisfied at the geometric discontinuity using conformal mapping and analytic continuation. In this study, we use only a relatively small amount of x-component displacement data of points away from the discontinuity of concern with their respective coordinates. Having this information we can easily obtain full-field stresses at the edge of the geometric discontinuity. Excellent results were obtained when the number of terms of the power series expansions, m=1. The maximum stress concentration calculation results using the present method and FEM using ANSYS agree well by less than one per cent difference. Experimental advantage of the method underscores the use of relatively small amount of data which are conveniently determined being away from the edge. Moreover, the small amount of measured input data needed affords the approach suitable for applications such as the multi-parameter concept used to obtain stress intensity factors from measured data. The use of laser speckle interferometry and moiré interferometry are also potential future related fields since the optical system for one-directional measurement is much simple.

  6. Fundamental supply of skin blood flow in the Chinese Han population: Measurements by a full-field laser perfusion imager.

    Science.gov (United States)

    Fei, W; Xu, S; Ma, J; Zhai, W; Cheng, S; Chang, Y; Wang, X; Gao, J; Tang, H; Yang, S; Zhang, X

    2018-05-08

    Skin blood flow is believed to link with many diseases, and shows a significant heterogeneity. There are several papers on basal cutaneous microcirculation perfusion in different races, while the data in Chinese is vacant. The aim was to establish the database of absolute fundamental supply of skin blood flow in the Chinese Han population. With a full-field laser perfusion imager (FLPI), the skin blood flow can be quantified. Cutaneous perfusion values were determined in 17 selected skin areas in 406 healthy participants aged between 20 and 80 years (mean 35.05 ± 11.33). Essential parameters such as weight, height were also measured and values of BMI were calculated. The perfusion values were reported in Arbitrary Perfusion Units (APU). The highest cutaneous perfusion value fell on eyelid (931.20 ± 242.59 in male and 967.83 ± 225.49 in female), and pretibial had the lowest value (89.09 ± 30.28 in male and 85.08 ± 33.59 in female). The values were higher in men than women on the bank of fingertips, nose, forehead, cheek, neck and earlobe (P < .05). Perfusion values on stretch and flexion side of forearm had negative correlation with age (P = .01 and P = 4.88 × 10 -3 , respectively) in male. Abdomen was negatively correlated with BMI in both gender (P = .02, respectively). Skin blood flow values vary with skin regions. There is a tendency to measure higher perfusion values in men than in women. And the values are irrelevant with age or BMI. © 2018 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  7. Mapping 3D breast lesions from full-field digital mammograms using subject-specific finite element models

    Science.gov (United States)

    García, E.; Oliver, A.; Diaz, O.; Diez, Y.; Gubern-Mérida, A.; Martí, R.; Martí, J.

    2017-03-01

    Patient-specific finite element (FE) models of the breast have received increasing attention due to the potential capability of fusing images from different modalities. During the Magnetic Resonance Imaging (MRI) to X-ray mammography registration procedure, the FE model is compressed mimicking the mammographic acquisition. Subsequently, suspicious lesions in the MRI volume can be projected into the 2D mammographic space. However, most registration algorithms do not provide the reverse information, avoiding to obtain the 3D geometrical information from the lesions localized in the mammograms. In this work we introduce a fast method to localize the 3D position of the lesion within the MRI, using both cranio-caudal (CC) and medio-lateral oblique (MLO) mammographic projections, indexing the tetrahedral elements of the biomechanical model by means of an uniform grid. For each marked lesion in the Full-Field Digital Mammogram (FFDM), the X-ray path from source to the marker is calculated. Barycentric coordinates are computed in the tetrahedrons traversed by the ray. The list of elements and coordinates allows to localize two curves within the MRI and the closest point between both curves is taken as the 3D position of the lesion. The registration errors obtained in the mammographic space are 9.89 +/- 3.72 mm in CC- and 8.04 +/- 4.68 mm in MLO-projection and the error in the 3D MRI space is equal to 10.29 +/- 3.99 mm. Regarding the uniform grid, it is computed spending between 0.1 and 0.7 seconds. The average time spent to compute the 3D location of a lesion is about 8 ms.

  8. Image quality of a wet laser printer versus a paper printer for full-field digital mammograms.

    Science.gov (United States)

    Schueller, Gerd; Kaindl, Elisabeth; Matzek, Wolfgang K; Semturs, Friedrich; Schueller-Weidekamm, Claudia; Helbich, Thomas H

    2006-01-01

    The purpose of our study was to compare the image quality of a wet laser printer with that of a paper printer for full-field digital mammography (FFDM). For both a wet laser printer and a paper printer connected to an FFDM system, image quality parameters were evaluated using a standardized printer test image (luminance density, dynamic range). The detectability of standardized objects on a phantom was also evaluated. Furthermore, 640 mammograms of 80 patients with different breast tissue composition patterns were imaged with both printers. Subjective image quality parameters (brightness, contrast, and detection of details of anatomic structures-that is, skin, subcutis, musculature, glandular tissue, and fat), the detectability of breast lesions (mass, calcifications), and the diagnostic performance according to the BI-RADS classification were evaluated. Both the luminance density and the dynamic range were superior for the wet laser printer. More standardized objects were visible on the phantom imaged with the wet laser printer than with the paper printer (13/16 vs 11/16). Each subjective image quality parameter of the mammograms from the wet laser printer was rated superior to those of the paper printer. Significantly more breast lesions were detected on the wet laser printer images than on the paper printer images (masses, 13 vs 10; calcifications, 65 vs 48; p printer images, BI-RADS 4 and 5 categories were underestimated for 10 (43.5%) of 23 patients. For FFDM, images obtained from a wet laser printer show superior objective and subjective image quality compared with a paper printer. As a consequence, the paper printer should not be used for FFDM.

  9. Validation of image quality in full-field digital mammography: Is the replacement of wet by dry laser printers justified?

    International Nuclear Information System (INIS)

    Schueller, Gerd; Kaindl, Elisabeth; Langenberger, Herbert; Stadler, Alfred; Schueller-Weidekamm, Claudia; Semturs, Friedrich; Helbich, Thomas H.

    2007-01-01

    Objective: Dry laser printers have replaced wet laser printers to produce hard copies of high-resolution digital images, primarily because of environmental concerns. However, no scientific research data have been published that compare the image quality of dry and wet laser printers in full-field digital mammography (FFDM). This study questions the image quality of these printers. Materials and methods: Objective image quality parameters of both printers were evaluated using a standardized printer test image, i.e., optical density and detectability of specific image elements (lines, curves, and shapes). Furthermore, mammograms of 129 patients with different breast tissue composition patterns were imaged with both printers. A total of 1806 subjective image quality parameters (brightness, contrast, and detail detection of anatomic structures), the detectability of breast lesions, as well as diagnostic performance according to the BI-RADS classification were evaluated. In addition, the presence of film artifacts was investigated. Results: Optical density values were equal for the dry and the wet laser printer. Detection of specific image elements on the printer test image was not different. Ratings of subjective image quality parameters were equal, as were the detectability of breast lesions and the diagnostic performance. Dry laser printer images showed more artifacts (164 versus 27). However, these artifacts did not influence image quality. Conclusion: Based on the evidence of objective and subjective parameters, a dry laser printer equals the image quality of a wet laser printer in FFDM. Therefore, not only for reasons of environmental preference, the replacement of wet laser printers by dry laser printers in FFDM is justified

  10. A comparison of the accuracy of film-screen mammography, full-field digital mammography, and digital breast tomosynthesis

    International Nuclear Information System (INIS)

    Michell, M.J.; Iqbal, A.; Wasan, R.K.; Evans, D.R.; Peacock, C.; Lawinski, C.P.; Douiri, A.; Wilson, R.; Whelehan, P.

    2012-01-01

    Aim: To measure the change in diagnostic accuracy of conventional film-screen mammography and full-field digital mammography (FFDM) with the addition of digital breast tomosynthesis (DBT) in women recalled for assessment following routine screening. Materials and methods: Ethics approval for the study was granted. Women recalled for assessment following routine screening with screen-film mammography were invited to participate. Participants underwent bilateral, two-view FFDM and two-view DBT. Readers scored each lesion separately for probability of malignancy on screen-film mammography, FFDM, and then DBT. The scores were compared with the presence or absence of malignancy based on the final histopathology outcome. Results: Seven hundred and thirty-eight women participated (93.2% recruitment rate). Following assessment 204 (26.8%) were diagnosed as malignant (147 invasive and 57 in-situ tumours), 286 (37.68%) as benign, and 269 (35.4%) as normal. The diagnostic accuracy was evaluated by using receiving operating characteristic (ROC) and measurement of area under the curve (AUC). The AUC values demonstrated a significant (p = 0.0001) improvement in the diagnostic accuracy with the addition of DBT combined with FFDM and film-screen mammography (AUC = 0.9671) when compared to FFDM plus film-screen mammography (AUC = 0.8949) and film-screen mammography alone (AUC = 0.7882). The effect was significantly greater for soft-tissue lesions [AUC was 0.9905 with the addition of DBT and AUC was 0.9201 for FFDM with film-screen mammography combined (p = 0.0001)] compared to microcalcification [with the addition of DBT (AUC = 0.7920) and for FFDM with film-screen mammography combined (AUC = 0.7843; p = 0.3182)]. Conclusion: The addition of DBT increases the accuracy of mammography compared to FFDM and film-screen mammography combined and film-screen mammography alone in the assessment of screen-detected soft-tissue mammographic abnormalities.

  11. Full-field measurement of micromotion around a cementless femoral stem using micro-CT imaging and radiopaque markers.

    Science.gov (United States)

    Malfroy Camine, V; Rüdiger, H A; Pioletti, D P; Terrier, A

    2016-12-08

    A good primary stability of cementless femoral stems is essential for the long-term success of total hip arthroplasty. Experimental measurement of implant micromotion with linear variable differential transformers is commonly used to assess implant primary stability in pre-clinical testing. But these measurements are often limited to a few distinct points at the interface. New techniques based on micro-computed tomography (micro-CT) have recently been introduced, such as Digital Volume Correlation (DVC) or markers-based approaches. DVC is however limited to measurement around non-metallic implants due to metal-induced imaging artifacts, and markers-based techniques are confined to a small portion of the implant. In this paper, we present a technique based on micro-CT imaging and radiopaque markers to provide the first full-field micromotion measurement at the entire bone-implant interface of a cementless femoral stem implanted in a cadaveric femur. Micromotion was measured during compression and torsion. Over 300 simultaneous measurement points were obtained. Micromotion amplitude ranged from 0 to 24µm in compression and from 0 to 49µm in torsion. Peak micromotion was distal in compression and proximal in torsion. The technique bias was 5.1µm and its repeatability standard deviation was 4µm. The method was thus highly reliable and compared well with results obtained with linear variable differential transformers (LVDTs) reported in the literature. These results indicate that this micro-CT based technique is perfectly relevant to observe local variations in primary stability around metallic implants. Possible applications include pre-clinical testing of implants and validation of patient-specific models for pre-operative planning. Copyright © 2016 Elsevier Ltd. All rights reserved.

  12. Panel surveys

    OpenAIRE

    MADRE, JL; ZUMKELLER, D; CHLOND, B; ARMOOGUM, J

    2004-01-01

    l'analyse du comportement humain constitue un enjeu important dans le domaine des transports, lequel se transforme radicalement sous la pression des évolutions économique, écologique et démographique. les premières grandes études ont commence il y a plus d'une dizaine d'années : parc auto sofres en france, puget sound panel a seattle. cet article fait le bilan de ces expériences et met en évidence les principaux problèmes méthodologiques rencontres tout en proposant de nouvelles directions d'...

  13. Screen-film mammography versus full-field digital mammography in a population-based screening program: The Sogn and Fjordane study

    International Nuclear Information System (INIS)

    Juel, Inger-Marie; Johannessen, Gunnar; Skaane, Per; Roth Hoff, Solveig; Hofvind, Solveig

    2010-01-01

    Background: Studies comparing analog and digital mammography in breast cancer screening have shown conflicting results. Little is known about the use of digital photon-counting detectors. Purpose: To retrospectively compare performance indicators in screen-film (SFM) and full-field digital mammography (FFDM) using a photon-counting detector in a population-based screening program. Material and Methods: The Norwegian Social Science Data Services approved the study, which was part of the Norwegian Breast Cancer Screening Program. The program invites women aged 50-69 years to two-view mammography biannually. The study period was January 2005 to June 2006 for SFM and August 2006 to December 2007 for FFDM. Independent double reading was performed using a five-point rating scale for probability of cancer. Recalls due to abnormal mammography were retrospectively reviewed by an expert panel. Performance indicators for the two techniques were compared. Attendance rate was 83.6% (7442/8901) for SFM and 82.0% (6932/8451) for FFDM. Results: The recall rate due to abnormal mammography, cancer detection rate and positive predictive value did not differ significantly between SFM and FFDM: recall 2.3% (174/7442) versus 2.4% (168/6932), cancer detection 0.39% (29/7442) versus 0.48% (33/6932), positive predictive value 16.7% (29/174) versus 19.6% (33/168), respectively (P>0.05 for all). The recall rate due to technically inadequate mammograms was 0.3% (19/7442) for SFM and 0.01% (1/6932) for FFDM. In the retrospective review, a significantly higher proportion of calcifications and asymmetric density were categorized as normal or definitively benign in FFDM compared with SFM. The average glandular dose was 2.17 mGy for SFM and 1.25 mGy for FFDM. Conclusion: Performance indicators show that FFDM using photon-counting detector is suitable for breast cancer screening. The lower radiation dose and lower recalls due to technically inadequate mammograms are of importance in mammography

  14. Full Field and Anomaly Initialisation using a low order climate model: a comparison, and proposals for advanced formulations

    Science.gov (United States)

    Weber, Robin; Carrassi, Alberto; Guemas, Virginie; Doblas-Reyes, Francisco; Volpi, Danila

    2014-05-01

    Full Field (FFI) and Anomaly Initialisation (AI) are two schemes used to initialise seasonal-to-decadal (s2d) prediction. FFI initialises the model on the best estimate of the actual climate state and minimises the initial error. However, due to inevitable model deficiencies, the trajectories drift away from the observations towards the model's own attractor, inducing a bias in the forecast. AI has been devised to tackle the impact of drift through the addition of this bias onto the observations, in the hope of gaining an initial state closer to the model attractor. Its goal is to forecast climate anomalies. The large variety of experimental setups, global coupled models, and observational networks adopted world-wide have led to varying results with regards to the relative performance of AI and FFI. Our research is firstly motivated in a comparison of these two initialisation approaches under varying circumstances of observational errors, observational distributions, and model errors. We also propose and compare two advanced schemes for s2d prediction. Least Square Initialisation (LSI) intends to propagate observational information of partially initialized systems to the whole model domain, based on standard practices in data assimilation and using the covariance of the model anomalies. Exploring the Parameters Uncertainty (EPU) is an online drift correction technique applied during the forecast run after initialisation. It is designed to estimate, and subtract, the bias in the forecast related to parametric error. Experiments are carried out using an idealized coupled dynamics in order to facilitate better control and robust statistical inference. Results show that an improvement of FFI will necessitate refinements in the observations, whereas improvements in AI are subject to model advances. A successful approximation of the model attractor using AI is guaranteed only when the differences between model and nature probability distribution functions (PDFs) are

  15. Quantitative comparison of clustered microcalcifications in for-presentation and for-processing mammograms in full-field digital mammography.

    Science.gov (United States)

    Wang, Juan; Nishikawa, Robert M; Yang, Yongyi

    2017-07-01

    Mammograms acquired with full-field digital mammography (FFDM) systems are provided in both "for-processing'' and "for-presentation'' image formats. For-presentation images are traditionally intended for visual assessment by the radiologists. In this study, we investigate the feasibility of using for-presentation images in computerized analysis and diagnosis of microcalcification (MC) lesions. We make use of a set of 188 matched mammogram image pairs of MC lesions from 95 cases (biopsy proven), in which both for-presentation and for-processing images are provided for each lesion. We then analyze and characterize the MC lesions from for-presentation images and compare them with their counterparts in for-processing images. Specifically, we consider three important aspects in computer-aided diagnosis (CAD) of MC lesions. First, we quantify each MC lesion with a set of 10 image features of clustered MCs and 12 textural features of the lesion area. Second, we assess the detectability of individual MCs in each lesion from the for-presentation images by a commonly used difference-of-Gaussians (DoG) detector. Finally, we study the diagnostic accuracy in discriminating between benign and malignant MC lesions from the for-presentation images by a pretrained support vector machine (SVM) classifier. To accommodate the underlying background suppression and image enhancement in for-presentation images, a normalization procedure is applied. The quantitative image features of MC lesions from for-presentation images are highly consistent with that from for-processing images. The values of Pearson's correlation coefficient between features from the two formats range from 0.824 to 0.961 for the 10 MC image features, and from 0.871 to 0.963 for the 12 textural features. In detection of individual MCs, the FROC curve from for-presentation is similar to that from for-processing. In particular, at sensitivity level of 80%, the average number of false-positives (FPs) per image region is 9

  16. Breast Imaging Reporting and Data System (BI-RADS) breast composition descriptors: Automated measurement development for full field digital mammography

    International Nuclear Information System (INIS)

    Fowler, E. E.; Sellers, T. A.; Lu, B.; Heine, J. J.

    2013-01-01

    Purpose: The Breast Imaging Reporting and Data System (BI-RADS) breast composition descriptors are used for standardized mammographic reporting and are assessed visually. This reporting is clinically relevant because breast composition can impact mammographic sensitivity and is a breast cancer risk factor. New techniques are presented and evaluated for generating automated BI-RADS breast composition descriptors using both raw and calibrated full field digital mammography (FFDM) image data.Methods: A matched case-control dataset with FFDM images was used to develop three automated measures for the BI-RADS breast composition descriptors. Histograms of each calibrated mammogram in the percent glandular (pg) representation were processed to create the new BR pg measure. Two previously validated measures of breast density derived from calibrated and raw mammograms were converted to the new BR vc and BR vr measures, respectively. These three measures were compared with the radiologist-reported BI-RADS compositions assessments from the patient records. The authors used two optimization strategies with differential evolution to create these measures: method-1 used breast cancer status; and method-2 matched the reported BI-RADS descriptors. Weighted kappa (κ) analysis was used to assess the agreement between the new measures and the reported measures. Each measure's association with breast cancer was evaluated with odds ratios (ORs) adjusted for body mass index, breast area, and menopausal status. ORs were estimated as per unit increase with 95% confidence intervals.Results: The three BI-RADS measures generated by method-1 had κ between 0.25–0.34. These measures were significantly associated with breast cancer status in the adjusted models: (a) OR = 1.87 (1.34, 2.59) for BR pg ; (b) OR = 1.93 (1.36, 2.74) for BR vc ; and (c) OR = 1.37 (1.05, 1.80) for BR vr . The measures generated by method-2 had κ between 0.42–0.45. Two of these measures were significantly

  17. Full-field and anomaly initialization using a low-order climate model: a comparison and proposals for advanced formulations

    Science.gov (United States)

    Carrassi, A.; Weber, R. J. T.; Guemas, V.; Doblas-Reyes, F. J.; Asif, M.; Volpi, D.

    2014-04-01

    Initialization techniques for seasonal-to-decadal climate predictions fall into two main categories; namely full-field initialization (FFI) and anomaly initialization (AI). In the FFI case the initial model state is replaced by the best possible available estimate of the real state. By doing so the initial error is efficiently reduced but, due to the unavoidable presence of model deficiencies, once the model is let free to run a prediction, its trajectory drifts away from the observations no matter how small the initial error is. This problem is partly overcome with AI where the aim is to forecast future anomalies by assimilating observed anomalies on an estimate of the model climate. The large variety of experimental setups, models and observational networks adopted worldwide make it difficult to draw firm conclusions on the respective advantages and drawbacks of FFI and AI, or to identify distinctive lines for improvement. The lack of a unified mathematical framework adds an additional difficulty toward the design of adequate initialization strategies that fit the desired forecast horizon, observational network and model at hand. Here we compare FFI and AI using a low-order climate model of nine ordinary differential equations and use the notation and concepts of data assimilation theory to highlight their error scaling properties. This analysis suggests better performances using FFI when a good observational network is available and reveals the direct relation of its skill with the observational accuracy. The skill of AI appears, however, mostly related to the model quality and clear increases of skill can only be expected in coincidence with model upgrades. We have compared FFI and AI in experiments in which either the full system or the atmosphere and ocean were independently initialized. In the former case FFI shows better and longer-lasting improvements, with skillful predictions until month 30. In the initialization of single compartments, the best

  18. Combined-load buckling behavior of metal-matrix composite sandwich panels under different thermal environments

    Science.gov (United States)

    Ko, William L.; Jackson, Raymond H.

    1991-01-01

    Combined compressive and shear buckling analysis was conducted on flat rectangular sandwich panels with the consideration of transverse shear effects of the core. The sandwich panel is fabricated with titanium honeycomb core and laminated metal matrix composite face sheets. The results show that the square panel has the highest combined load buckling strength, and that the buckling strength decreases sharply with the increases of both temperature and panel aspect ratio. The effect of layup (fiber orientation) on the buckling strength of the panels was studied in detail. The metal matrix composite sandwich panel was much more efficient than the sandwich panel with nonreinforced face sheets and had the same specific weight.

  19. Population-based mammography screening: comparison of screen-film and full-field digital mammography with soft-copy reading--Oslo I study.

    Science.gov (United States)

    Skaane, Per; Young, Kari; Skjennald, Arnulf

    2003-12-01

    To compare screen-film and full-field digital mammography with soft-copy reading in a population-based screening program. Full-field digital and screen-film mammography were performed in 3,683 women aged 50-69 years. Two standard views of each breast were acquired with each modality. Images underwent independent double reading with use of a five-point rating scale for probability of cancer. Recall rates and positive predictive values were calculated. Cancer detection rates determined with both modalities were compared by using the McNemar test for paired proportions. Retrospective side-by-side analysis for conspicuity of cancers was performed by an external independent radiologist group with experience in both modalities. In 3,683 cases, 31 cancers were detected. Screen-film mammography depicted 28 (0.76%) malignancies, and full-field digital mammography depicted 23 (0.62%) malignancies. The difference between cancer detection rates was not significant (P =.23). The recall rate for full-field digital mammography (4.6%; 168 of 3,683 cases) was slightly higher than that for screen-film mammography (3.5%; 128 of 3,683 cases). The positive predictive value based on needle biopsy results was 46% for screen-film mammography and 39% for full-field digital mammography. Side-by-side image comparison for cancer conspicuity led to classification of 19 cancers as equal for probability of malignancy, six cancers as slightly better demonstrated at screen-film mammography, and six cancers as slightly better demonstrated at full-field digital mammography. There was no statistically significant difference in cancer detection rate between screen-film and full-field digital mammography. Cancer conspicuity was equal with both modalities. Full-field digital mammography with soft-copy reading is comparable to screen-film mammography in population-based screening.

  20. Flat feet in children

    Directory of Open Access Journals (Sweden)

    Vukašinović Zoran

    2009-01-01

    Full Text Available The authors describe flatfoot, as one of very frequent deformities in everyday medical practice. A special condition of the deformity associated with a calcaneal valgus position and complicated by a knee valgus position (as a consequence of non-treatment is described. Also, the precise anatomy of the longitudinal foot arches (medial and lateral, definition and classification of the deformity, clinical findings and therapeutic protocols are proposed. The authors especially emphasise that the need for having extensive knowledge on the differences between a flexible and rigid flatfoot, having in mind that the treatment of flexible flat foot is usually not necessary, while the treatment of rigid flatfoot is usually unavoidable.

  1. Flat Surface Damage Detection System (FSDDS)

    Science.gov (United States)

    Williams, Martha; Lewis, Mark; Gibson, Tracy; Lane, John; Medelius, Pedro; Snyder, Sarah; Ciarlariello, Dan; Parks, Steve; Carrejo, Danny; Rojdev, Kristina

    2013-01-01

    The Flat Surface Damage Detection system (FSDDS} is a sensory system that is capable of detecting impact damages to surfaces utilizing a novel sensor system. This system will provide the ability to monitor the integrity of an inflatable habitat during in situ system health monitoring. The system consists of three main custom designed subsystems: the multi-layer sensing panel, the embedded monitoring system, and the graphical user interface (GUI). The GUI LABVIEW software uses a custom developed damage detection algorithm to determine the damage location based on the sequence of broken sensing lines. It estimates the damage size, the maximum depth, and plots the damage location on a graph. Successfully demonstrated as a stand alone technology during 2011 D-RATS. Software modification also allowed for communication with HDU avionics crew display which was demonstrated remotely (KSC to JSC} during 2012 integration testing. Integrated FSDDS system and stand alone multi-panel systems were demonstrated remotely and at JSC, Mission Operations Test using Space Network Research Federation (SNRF} network in 2012. FY13, FSDDS multi-panel integration with JSC and SNRF network Technology can allow for integration with other complementary damage detection systems.

  2. Ricci-flat branes

    International Nuclear Information System (INIS)

    Brecher, D.; Perry, M.J.

    2000-01-01

    Up to overall harmonic factors, the D8-brane solution of the massive type IIA supergravity theory is the product of nine-dimensional Minkowski space (the world-volume) with the real line (the transverse space). We show that the equations of motion allow for the world-volume metric to be generalised to an arbitrary Ricci-flat one. If this nine-dimensional Ricci-flat manifold admits Killing spinors, then the resulting solutions are supersymmetric and satisfy the usual Bogomol'nyi bound, although they preserve fewer than the usual one half of the supersymmetries. We describe the possible choices of such manifolds, elaborating on the connection between the existence of Killing spinors and the self-duality condition on the curvature two-form. Since the D8-brane is a domain wall in ten dimensions, we are led to consider the general case: domain walls in any supergravity theory. Similar considerations hold here also. Moreover, it is shown that the world-volume of any magnetic brane - of which the domain walls are a specific example - can be generalised in precisely the same way. The general class of supersymmetric solutions have gravitational instantons as their spatial sections. Some mention is made of the world-volume solitons of such branes

  3. Flat Engineered Multichannel Reflectors

    Directory of Open Access Journals (Sweden)

    V. S. Asadchy

    2017-09-01

    Full Text Available Recent advances in engineered gradient metasurfaces have enabled unprecedented opportunities for light manipulation using optically thin sheets, such as anomalous refraction, reflection, or focusing of an incident beam. Here, we introduce a concept of multichannel functional metasurfaces, which are able to control incoming and outgoing waves in a number of propagation directions simultaneously. In particular, we reveal a possibility to engineer multichannel reflectors. Under the assumption of reciprocity and energy conservation, we find that there exist three basic functionalities of such reflectors: specular, anomalous, and retroreflections. Multichannel response of a general flat reflector can be described by a combination of these functionalities. To demonstrate the potential of the introduced concept, we design and experimentally test three different multichannel reflectors: three- and five-channel retroreflectors and a three-channel power splitter. Furthermore, by extending the concept to reflectors supporting higher-order Floquet harmonics, we forecast the emergence of other multichannel flat devices, such as isolating mirrors, complex splitters, and multi-functional gratings.

  4. Flat Engineered Multichannel Reflectors

    Science.gov (United States)

    Asadchy, V. S.; Díaz-Rubio, A.; Tcvetkova, S. N.; Kwon, D.-H.; Elsakka, A.; Albooyeh, M.; Tretyakov, S. A.

    2017-07-01

    Recent advances in engineered gradient metasurfaces have enabled unprecedented opportunities for light manipulation using optically thin sheets, such as anomalous refraction, reflection, or focusing of an incident beam. Here, we introduce a concept of multichannel functional metasurfaces, which are able to control incoming and outgoing waves in a number of propagation directions simultaneously. In particular, we reveal a possibility to engineer multichannel reflectors. Under the assumption of reciprocity and energy conservation, we find that there exist three basic functionalities of such reflectors: specular, anomalous, and retroreflections. Multichannel response of a general flat reflector can be described by a combination of these functionalities. To demonstrate the potential of the introduced concept, we design and experimentally test three different multichannel reflectors: three- and five-channel retroreflectors and a three-channel power splitter. Furthermore, by extending the concept to reflectors supporting higher-order Floquet harmonics, we forecast the emergence of other multichannel flat devices, such as isolating mirrors, complex splitters, and multi-functional gratings.

  5. Panel Discussion

    Science.gov (United States)

    Langer, James

    1997-03-01

    Panelists: Arthur Bienenstock, Stanford University Cherry Ann Murray, Lucent Technologies Venkatesh Narayanamurti, University of California-Santa Barbara Paul Peercy, SEMI-SEMATECH Robert Richardson, Cornell University James Roberto, Oak Ridge National Laboratory The Board on Physics and Astronomy is undertaking a series of reassessments of all branches of physics as the foundation of a new physics survey. As part of this project, a Committee on Condensed Matter and Materials Physics has been established under the leadership of Venkatesh Narayanamurti of the University of California-Santa Barbara. The committee has been working since June on a study that will include an illustrative recounting of major recent achievements; identification of new opportunities and challenges facing the field; and articulation-for leaders in government, industry, universities, and the public at large-of the important roles played by the field in modern society. An especially urgent issue is how to maintain the intellectual vitality of condensed matter and materials physics, and its contributions to the well-being of the United States, in an era of limited resources. The forum will feature a panel of materials researchers who are members of the Committee on Condensed Matter and Materials Physics. They will give a brief report on the status of the study and engage in a dialogue with the audience about issues facing the condensed matter and materials physics community. Broad community input is vital to the success of the study. Please come and make your voice heard!

  6. UVIS Flat Field Uniformity

    Science.gov (United States)

    Quijano, Jessica Kim

    2009-07-01

    The stability and uniformity of the low-frequency flat fields {L-flat} of the UVIS detector will be assessed by using multiple-pointing observations of the globular clusters 47 Tucanae {NGC104} and Omega Centauri {NGC5139}, thus imaging moderately dense stellar fields. By placing the same star over different portions of the detector and measuring relative changes in its brightness, it will be possible to determine local variations in the response of the UVIS detector. Based on previous experience with STIS and ACS, it is deemed that a total of 9 different pointings will suffice to provide adequate characterization of the flat field stability in any given band. For each filter to be tested, the baseline consists of 9 pointings in a 3X3 box pattern with dither steps of about 25% of the FOV, or 40.5", in either the x or y direction {useful also for CTE measurements, if needed in the future}. During SMOV, the complement of filters to be tested is limited to the following 6 filters: F225W, F275W, F336W, for Omega Cen, and F438W, F606W, and F814W for 47 Tuc. Three long exposures for each target are arranged such that the initial dither position is observed with the appropriate filters for that target within one orbit at a single pointing, so that filter-to-filter differences in the observed star positions can be checked. In addition to the 9 baseline exposures, two sets of short exposures will be taken:a} one short exposure will be taken of OmegaCen with each of the visible filters {F438W, F606W and F814W} in order to check the geometric distortion solution to be obtained with the data from proposal 11444;b} for each target, a single short exposure will be taken with each filter to facilitate the study of the PSF as a function of position on the detector by providing unsaturated images of sparsely-spaced bright stars.This proposal corresponds to Activity Description ID WF39. It should execute only after the following proposal has executed:WF21 - 11434

  7. Hepatic (Liver) Function Panel

    Science.gov (United States)

    ... Educators Search English Español Blood Test: Hepatic (Liver) Function Panel KidsHealth / For Parents / Blood Test: Hepatic (Liver) ... kidneys ) is working. What Is a Hepatic (Liver) Function Panel? A liver function panel is a blood ...

  8. Comprehensive metabolic panel

    Science.gov (United States)

    Metabolic panel - comprehensive; Chem-20; SMA20; Sequential multi-channel analysis with computer-20; SMAC20; Metabolic panel 20 ... Chernecky CC, Berger BJ. Comprehensive metabolic panel (CMP) - blood. In: ... Tests and Diagnostic Procedures . 6th ed. St Louis, MO: ...

  9. Brushless Cleaning of Solar Panels and Windows

    Science.gov (United States)

    Schneider, H. W.

    1982-01-01

    Machine proposed for cleaning solar panels and reflectors uses multiple vortexes of air, solvent, and water to remove dust and dirt. Uses no brushes that might abrade solar surfaces and thereby reduce efficiency. Machine can be readily automated and can be used on curved surfaces such as aparbolic reflectors as well as on flat ones. Cleaning fluids are recycled, so that large quantities of water and solvent are not needed.

  10. Exact piecewise flat gravitational waves

    NARCIS (Netherlands)

    van de Meent, M.

    2011-01-01

    We generalize our previous linear result (van de Meent 2011 Class. Quantum Grav 28 075005) in obtaining gravitational waves from our piecewise flat model for gravity in 3+1 dimensions to exact piecewise flat configurations describing exact planar gravitational waves. We show explicitly how to

  11. Flat plate collector. Solarflachkollektor

    Energy Technology Data Exchange (ETDEWEB)

    Raab, N

    1979-03-29

    The invention refers to a flat solar collector with an absorber plate, which is arranged on a support and is covered by a transparent window, between which and the plate there is an air space. The previously known structures of this type had the disadvantage that the thermal expansion of the enclosed air caused considerable difficulties. The purpose of the invention is therefore to create a collector, which can be used on the modular system, retains its properties and is safe in spite of the great temperature variations. According to the invention this problem is solved by providing a compensating space in the collector, which is separated by a diaphragm from the airspace between the plate and the covering window. The airspace therefore remains sealed against the atmosphere, so that no dirt, corrosion of the inside and no condensation can reduce the efficiency of the collector. A rise in pressure due to an increase in temperature is immediately reduced by expansion of the diaphragm, which enters the compensation space. In order to increase the pressure in the airspace above the plate for increases in temperature, the compensation space is connected to the atmosphere. The diaphragm can be mirrored on the side towards the absorber, which makes the diaphragm into an insulating element, as it reflects radiated heat from the absorber.

  12. Evaluation of patient dose saving in grid-less x-ray mammography acquisition compared with full field digital mammography (FFDMG) acquisition

    DEFF Research Database (Denmark)

    Abdi, Ahmed Jibril; Mussmann, Bo Redder

    2017-01-01

    to investigate the dose saving in grid-less acquisition compared with conventional full-field digital mammography (FFDMG) acquisitions. A Piranha 657 was used to measure the entrance exposure. The entrance exposure was directly measured on different PMMA thicknesses of 20-70mm in steps of 10mm. The PMMA block...

  13. 40 CFR 230.42 - Mud flats.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Mud flats. 230.42 Section 230.42... Aquatic Sites § 230.42 Mud flats. (a) Mud flats are broad flat areas along the sea coast and in coastal rivers to the head of tidal influence and in inland lakes, ponds, and riverine systems. When mud flats...

  14. APPLIED ORIGAMI. Origami of thick panels.

    Science.gov (United States)

    Chen, Yan; Peng, Rui; You, Zhong

    2015-07-24

    Origami patterns, including the rigid origami patterns in which flat inflexible sheets are joined by creases, are primarily created for zero-thickness sheets. In order to apply them to fold structures such as roofs, solar panels, and space mirrors, for which thickness cannot be disregarded, various methods have been suggested. However, they generally involve adding materials to or offsetting panels away from the idealized sheet without altering the kinematic model used to simulate folding. We develop a comprehensive kinematic synthesis for rigid origami of thick panels that differs from the existing kinematic model but is capable of reproducing motions identical to that of zero-thickness origami. The approach, proven to be effective for typical origami, can be readily applied to fold real engineering structures. Copyright © 2015, American Association for the Advancement of Science.

  15. Flat H Redundant Frangible Joint Development

    Science.gov (United States)

    Brown, Chris

    2016-01-01

    changes to better disperse loads paths and to minimize air gaps. The design additionally added more structural strength to enhance the structural limits in static loads testing. The design also implemented a smoother load line through the assembly. Results / Knowledge Gained The new Flat H RFJ successfully fractured at WSTF with thicker ligaments and lower cord size. Where failure to separate occurred earlier, there is now excessive energy available for structural separation. The new challenge to provide some structural support to prevent secondary fracturing of the break plate remains to be completed. This future work is being funded by the JSC Engineering Directorate in 2017 to elevate the TRL on curved Flat H RFJs that configure with the Orion Service Panel Separation. Additional funding from JSC Engineering will provide new design testing to avoid secondary fracturing.

  16. Anti-Stokes effect CCD camera and SLD based optical coherence tomography for full-field imaging in the 1550nm region

    Science.gov (United States)

    Kredzinski, Lukasz; Connelly, Michael J.

    2012-06-01

    Full-field Optical coherence tomography is an en-face interferometric imaging technology capable of carrying out high resolution cross-sectional imaging of the internal microstructure of an examined specimen in a non-invasive manner. The presented system is based on competitively priced optical components available at the main optical communications band located in the 1550 nm region. It consists of a superluminescent diode and an anti-stokes imaging device. The single mode fibre coupled SLD was connected to a multi-mode fibre inserted into a mode scrambler to obtain spatially incoherent illumination, suitable for OCT wide-field modality in terms of crosstalk suppression and image enhancement. This relatively inexpensive system with moderate resolution of approximately 24um x 12um (axial x lateral) was constructed to perform a 3D cross sectional imaging of a human tooth. To our knowledge this is the first 1550 nm full-field OCT system reported.

  17. Evaluation of low-energy contrast-enhanced spectral mammography images by comparing them to full-field digital mammography using EUREF image quality criteria

    OpenAIRE

    Lalji, U. C.; Jeukens, C. R. L. P. N.; Houben, I.; Nelemans, P. J.; van Engen, R. E.; van Wylick, E.; Beets-Tan, R. G. H.; Wildberger, J. E.; Paulis, L. E.; Lobbes, M. B. I.

    2015-01-01

    Objective Contrast-enhanced spectral mammography (CESM) examination results in a low-energy (LE) and contrast-enhanced image. The LE appears similar to a full-field digital mammogram (FFDM). Our aim was to evaluate LE CESM image quality by comparing it to FFDM using criteria defined by the European Reference Organization for Quality Assured Breast Screening and Diagnostic Services (EUREF). Methods A total of 147 cases with both FFDM and LE images were independently scored by two experienced r...

  18. Feasibility for the Use of Flat Booster Reflectors in Various Photovoltaic Installations

    OpenAIRE

    Gelegenis, John Joachim; Axaopoulos, Petros; Misailidis, Stavros; Giannakidis, George; Samarakou, Maria; Bonaros, Bassilios

    2016-01-01

    The feasibility for the addition of flat booster reflectors to PV panels is techno-economically investigated for various applications (building attached PVs, ground installations, grid-connected or stand-alone units) and various PV types (mono-crystalline and amorphous silicon PV panels). A model developed to this aim is applied to optimize the parameters of the PV/reflector module and to evaluate its applicability according to the solar radiation data of Athens (Greece). The reflectors may l...

  19. Flat slices in Minkowski space

    Science.gov (United States)

    Murchadha, Niall Ó.; Xie, Naqing

    2015-03-01

    Minkowski space, flat spacetime, with a distance measure in natural units of d{{s}2}=-d{{t}2}+d{{x}2}+d{{y}2}+d{{z}2}, or equivalently, with spacetime metric diag(-1, +1, +1, +1), is recognized as a fundamental arena for physics. The Poincaré group, the set of all rigid spacetime rotations and translations, is the symmetry group of Minkowski space. The action of this group preserves the form of the spacetime metric. Each t = constant slice of each preferred coordinate system is flat. We show that there are also nontrivial non-singular representations of Minkowski space with complete flat slices. If the embedding of the flat slices decays appropriately at infinity, the only flat slices are the standard ones. However, if we remove the decay condition, we find non-trivial flat slices with non-vanishing extrinsic curvature. We write out explicitly the coordinate transformation to a frame with such slices.

  20. Hepatitis virus panel

    Science.gov (United States)

    ... page: //medlineplus.gov/ency/article/003558.htm Hepatitis virus panel To use the sharing features on this page, please enable JavaScript. The hepatitis virus panel is a series of blood tests used ...

  1. Antinuclear antibody panel

    Science.gov (United States)

    ... page: //medlineplus.gov/ency/article/003535.htm Antinuclear antibody panel To use the sharing features on this page, please enable JavaScript. The antinuclear antibody panel is a blood test that looks at ...

  2. Paneling architectural freeform surfaces

    KAUST Repository

    Eigensatz, Michael; Kilian, Martin; Schiftner, Alexander; Mitra, Niloy J.; Pottmann, Helmut; Pauly, Mark

    2010-01-01

    with a selected technology at reasonable cost, while meeting the design intent and achieving the desired aesthetic quality of panel layout and surface smoothness. The production of curved panels is mostly based on molds. Since the cost of mold fabrication

  3. [Comparison of dignity determination of mammographic microcalcification with two systems for digital full-field mammography with different detector resolution: a retrospective clinical study].

    Science.gov (United States)

    Schulz-Wendtland, R; Hermann, K-P; Adamietz, B; Meier-Meitinger, M; Wenkel, E; Lell, M; Anders, K; Uder, M

    2011-02-01

    The aim of this retrospective clinical study was to compare the diagnostic accuracy of the novel 50 µm FFDM (full-field digital mammography) system (DR) with an established 70 µm system (DR) in the differential diagnosis between benign and malignant clusters of microcalcification (n=50) (BI-RADS™ classification 4/5) and to assess the possible incremental value of the 50 µm pixel-pitch on specificity. From March 2009 to September 2009, 50 patients underwent full-field digital mammography (FFDM) (detector resolution 70 µm) (Novation, Siemens, Erlangen, Germany). As there were suspicious signs of microcalcification classified with BI-RADS™ 4/5 after diagnosis and preoperative wire localization, control images were made with the new FFDM system (detector: resolution 50 µm) (Amulet, Fujifilm, Tokyo, Japan) with the same exposure parameters. The diagnosis was determined after the operation by five radiologists with different experience in digital mammography from randomly distributed mediolateral views (monitor reading) whose results were correlated with the final histology of all lesions. Histopathology revealed 19 benign and 31 malignant lesions in 50 patients after open biopsy. The results of the five readers showed a higher sensitivity of the new FFDM system (80.0%) in the ability to recognize malignant microcalcification in comparison to the established system (74.8%). The specificity (75.8 versus 71.6%) was slightly higher for the new system but these results were not statistically significant (pdetector: resolution 50 µm) was also slightly superior to the well-known system (detector: resolution 70 µm) (80.1% versus 76.4%). Our study has shown that the new full-field digital mammography system using the novel detector compared with the already established FFDM system with respect to the assessment of microcalcification is at least equivalent.

  4. Trace Element Mapping of a Biological Specimen by a Full-Field X-ray Fluorescence Imaging Microscope with a Wolter Mirror

    International Nuclear Information System (INIS)

    Hoshino, Masato; Yamada, Norimitsu; Ishino, Toyoaki; Namiki, Takashi; Watanabe, Norio; Aoki, Sadao

    2007-01-01

    A full-field X-ray fluorescence imaging microscope with a Wolter mirror was applied to the element mapping of alfalfa seeds. The X-ray fluorescence microscope was built at the Photon Factory BL3C2 (KEK). X-ray fluorescence images of several growing stages of the alfalfa seeds were obtained. X-ray fluorescence energy spectra were measured with either a solid state detector or a CCD photon counting method. The element distributions of iron and zinc which were included in the seeds were obtained using a photon counting method

  5. Realization of the purely spatial Einstein-Podolsky-Rosen paradox in full-field images of spontaneous parametric down-conversion

    Science.gov (United States)

    Moreau, Paul-Antoine; Mougin-Sisini, Joé; Devaux, Fabrice; Lantz, Eric

    2012-07-01

    We demonstrate Einstein-Podolsky-Rosen (EPR) entanglement by detecting purely spatial quantum correlations in the near and far fields of spontaneous parametric down-conversion generated in a type-2 beta barium borate crystal. Full-field imaging is performed in the photon-counting regime with an electron-multiplying CCD camera. The data are used without any postselection, and we obtain a violation of Heisenberg inequalities with inferred quantities taking into account all the biphoton pairs in both the near and far fields by integration on the entire two-dimensional transverse planes. This ensures a rigorous demonstration of the EPR paradox in its original position-momentum form.

  6. Brain refractive index measured in vivo with high-NA defocus-corrected full-field OCT and consequences for two-photon microscopy.

    Science.gov (United States)

    Binding, Jonas; Ben Arous, Juliette; Léger, Jean-François; Gigan, Sylvain; Boccara, Claude; Bourdieu, Laurent

    2011-03-14

    Two-photon laser scanning microscopy (2PLSM) is an important tool for in vivo tissue imaging with sub-cellular resolution, but the penetration depth of current systems is potentially limited by sample-induced optical aberrations. To quantify these, we measured the refractive index n' in the somatosensory cortex of 7 rats in vivo using defocus optimization in full-field optical coherence tomography (ff-OCT). We found n' to be independent of imaging depth or rat age. From these measurements, we calculated that two-photon imaging beyond 200 µm into the cortex is limited by spherical aberration, indicating that adaptive optics will improve imaging depth.

  7. Wetting of flat gradient surfaces.

    Science.gov (United States)

    Bormashenko, Edward

    2018-04-01

    Gradient, chemically modified, flat surfaces enable directed transport of droplets. Calculation of apparent contact angles inherent for gradient surfaces is challenging even for atomically flat ones. Wetting of gradient, flat solid surfaces is treated within the variational approach, under which the contact line is free to move along the substrate. Transversality conditions of the variational problem give rise to the generalized Young equation valid for gradient solid surfaces. The apparent (equilibrium) contact angle of a droplet, placed on a gradient surface depends on the radius of the contact line and the values of derivatives of interfacial tensions. The linear approximation of the problem is considered. It is demonstrated that the contact angle hysteresis is inevitable on gradient surfaces. Electrowetting of gradient surfaces is discussed. Copyright © 2018 Elsevier Inc. All rights reserved.

  8. Effects of fire retardants on physical, mechanical, and fire properties of flat-pressed WPCs

    Science.gov (United States)

    Nadir Ayrilmis; Jan T. Benthien; Heiko Thoemen; Robert H. White

    2012-01-01

    Physical, mechanical, and fire properties of the flat-pressed wood plastic composites (WPCs) incorporated with various fire retardants (10% by weight) at different levels of wood flour (WF) content, 40, 50, or 60 wt%, were investigated. The WPC panels were made from dry-blended WF, polypropylene (PP), and fire retardant (FR) powders with maleic anhydride-grafted PP (2...

  9. Properties of flat-pressed wood plastic composites containing fire retardants

    Science.gov (United States)

    Nadir Ayrilmis; Jan. T. Benthien; Heiko Thoemen; Robert H. White

    2011-01-01

    This study investigated physical, mechanical, and fire properties of the flat-pressed wood plastic composites (WPCs) incorporated with various fire retardants (FRs) [5 or 15% by weight (wt)] at 50 wt % of the wood flour (WF). The WPC panels were made from dry-blended WF, polypropylene (PP) with maleic anhydride grafted PP (2 wt %), and FR powder formulations using a...

  10. Full-field mapping of internal strain distribution in red sandstone specimen under compression using digital volumetric speckle photography and X-ray computed tomography

    Directory of Open Access Journals (Sweden)

    Lingtao Mao

    2015-04-01

    Full Text Available It is always desirable to know the interior deformation pattern when a rock is subjected to mechanical load. Few experimental techniques exist that can represent full-field three-dimensional (3D strain distribution inside a rock specimen. And yet it is crucial that this information is available for fully understanding the failure mechanism of rocks or other geomaterials. In this study, by using the newly developed digital volumetric speckle photography (DVSP technique in conjunction with X-ray computed tomography (CT and taking advantage of natural 3D speckles formed inside the rock due to material impurities and voids, we can probe the interior of a rock to map its deformation pattern under load and shed light on its failure mechanism. We apply this technique to the analysis of a red sandstone specimen under increasing uniaxial compressive load applied incrementally. The full-field 3D displacement fields are obtained in the specimen as a function of the load, from which both the volumetric and the deviatoric strain fields are calculated. Strain localization zones which lead to the eventual failure of the rock are identified. The results indicate that both shear and tension are contributing factors to the failure mechanism.

  11. Comparison of dignity determination of mammographic microcalcification with two systems for digital full-field mammography with different detector resolution. A retrospective clinical study

    International Nuclear Information System (INIS)

    Schulz-Wendtland, R.; Adamietz, B.; Meier-Meitinger, M.; Wenkel, E.; Lell, M.; Anders, K.; Uder, M.; Hermann, K.P.

    2011-01-01

    The aim of this retrospective clinical study was to compare the diagnostic accuracy of the novel 50 μm FFDM (full-field digital mammography) system (DR) with an established 70 μm system (DR) in the differential diagnosis between benign and malignant clusters of microcalcification (n=50) (BI-RADS trademark classification 4/5) and to assess the possible incremental value of the 50 μm pixel-pitch on specificity. From March 2009 to September 2009, 50 patients underwent full-field digital mammography (FFDM) (detector resolution 70 μm) (Novation, Siemens, Erlangen, Germany). As there were suspicious signs of microcalcification classified with BI-RADS trademark 4/5 after diagnosis and preoperative wire localization, control images were made with the new FFDM system (detector: resolution 50 μm) (Amulet, Fujifilm, Tokyo, Japan) with the same exposure parameters. The diagnosis was determined after the operation by five radiologists with different experience in digital mammography from randomly distributed mediolateral views (monitor reading) whose results were correlated with the final histology of all lesions. Histopathology revealed 19 benign and 31 malignant lesions in 50 patients after open biopsy. The results of the five readers showed a higher sensitivity of the new FFDM system (80.0%) in the ability to recognize malignant microcalcification in comparison to the established system (74.8%). The specificity (75.8 versus 71.6%) was slightly higher for the new system but hese results were not statistically significant (p [de

  12. Paneling architectural freeform surfaces

    KAUST Repository

    Eigensatz, Michael

    2010-07-26

    The emergence of large-scale freeform shapes in architecture poses big challenges to the fabrication of such structures. A key problem is the approximation of the design surface by a union of patches, socalled panels, that can be manufactured with a selected technology at reasonable cost, while meeting the design intent and achieving the desired aesthetic quality of panel layout and surface smoothness. The production of curved panels is mostly based on molds. Since the cost of mold fabrication often dominates the panel cost, there is strong incentive to use the same mold for multiple panels. We cast the major practical requirements for architectural surface paneling, including mold reuse, into a global optimization framework that interleaves discrete and continuous optimization steps to minimize production cost while meeting user-specified quality constraints. The search space for optimization is mainly generated through controlled deviation from the design surface and tolerances on positional and normal continuity between neighboring panels. A novel 6-dimensional metric space allows us to quickly compute approximate inter-panel distances, which dramatically improves the performance of the optimization and enables the handling of complex arrangements with thousands of panels. The practical relevance of our system is demonstrated by paneling solutions for real, cutting-edge architectural freeform design projects. © 2010 ACM.

  13. Paneling architectural freeform surfaces

    KAUST Repository

    Eigensatz, Michael

    2010-07-25

    The emergence of large-scale freeform shapes in architecture poses big challenges to the fabrication of such structures. A key problem is the approximation of the design surface by a union of patches, so-called panels, that can be manufactured with a selected technology at reasonable cost, while meeting the design intent and achieving the desired aesthetic quality of panel layout and surface smoothness. The production of curved panels is mostly based on molds. Since the cost of mold fabrication often dominates the panel cost, there is strong incentive to use the same mold for multiple panels. We cast the major practical requirements for architectural surface paneling, including mold reuse, into a global optimization framework that interleaves discrete and continuous optimization steps to minimize production cost while meeting user-specified quality constraints. The search space for optimization is mainly generated through controlled deviation from the design surface and tolerances on positional and normal continuity between neighboring panels. A novel 6-dimensional metric space allows us to quickly compute approximate inter-panel distances, which dramatically improves the performance of the optimization and enables the handling of complex arrangements with thousands of panels. The practical relevance of our system is demonstrated by paneling solutions for real, cutting-edge architectural freeform design projects.

  14. Soil decontamination at Rocky Flats

    International Nuclear Information System (INIS)

    Olsen, R.L.; Hayden, J.A.; Alford, C.E.; Kochen, R.L.; Stevens, J.R.

    1979-01-01

    A soils decontamination project was initiated, to remove actinides from soils at Rocky Flats. Wet screening, attrition scrubbing with Calgon at high pH, attrition scrubbing at low pH, and cationic flotation were investigated. Pilot plant studies were carried out. Conceptual designs have been generated for mounting the process in semi-trailers

  15. REINFORCED COMPOSITE PANEL

    DEFF Research Database (Denmark)

    2003-01-01

    A composite panel having front and back faces, the panel comprising facing reinforcement, backing reinforcement and matrix material binding to the facing and backing reinforcements, the facing and backing reinforcements each independently comprising one or more reinforcing sheets, the facing rein...... by matrix material, the facing and backing reinforcements being interconnected to resist out-of-plane relative movement. The reinforced composite panel is useful as a barrier element for shielding structures, equipment and personnel from blast and/or ballistic impact damage....

  16. Solar reflection panels

    Science.gov (United States)

    Diver, Jr., Richard B.; Grossman, James W [Albuquerque, NM; Reshetnik, Michael [Boulder, CO

    2006-07-18

    A solar collector comprising a glass mirror, and a composite panel, wherein the back of the mirror is affixed to a front surface of the composite panel. The composite panel comprises a front sheet affixed to a surface of a core material, preferably a core material comprising a honeycomb structure, and a back sheet affixed to an opposite surface of the core material. The invention may further comprise a sealing strip, preferably comprising EPDM, positioned between the glass mirror and the front surface of the composite panel. The invention also is of methods of making such solar collectors.

  17. Individual energy savings for individual flats in blocks of flats

    DEFF Research Database (Denmark)

    Nielsen, Anker; Rose, Jørgen

    2014-01-01

    and 1980. Normally, we expect the reduction in energy consumption to be around 20% for a 2 °C lower temperature, but for an inner flat the reduction can be up to 71%. The owners of the adjoining flats get an increase in energy demand of 10 to 20% each. They will not be able to figure out whether...... this is because the neighbour maintains a low temperature or the fact that they maintain a higher temperature. The best solution is to keep your own indoor temperature low. We can also turn the problem around: if you maintain a higher temperature than your neighbours, then you will pay part of their heating bill....

  18. 3D nanoscale imaging of the yeast, Schizosaccharomyces pombe, by full-field transmission x-ray microscopy at 5.4 keV

    Science.gov (United States)

    Chen, Jie; Yang, Yunhao; Zhang, Xiaobo; Andrews, Joy C.; Pianetta, Piero; Guan, Yong; Liu, Gang; Xiong, Ying; Wu, Ziyu; Tian, Yangchao

    2010-01-01

    Three-dimensional (3D) nanoscale structures of the fission yeast, Schizosaccharomyces pombe, can be obtained by full-field transmission hard x-ray microscopy with 30 nm resolution using synchrotron radiation sources. Sample preparation is relatively simple and the samples are portable across various imaging environments, allowing for high throughput sample screening. The yeast cells were fixed and double stained with Reynold’s lead citrate and uranyl acetate. We performed both absorption contrast and Zernike phase contrast imaging on these cells in order to test this method. The membranes, nucleus and subcellular organelles of the cells were clearly visualized using absorption contrast mode. The x-ray images of the cells could be used to study the spatial distributions of the organelles in the cells. These results show unique structural information, demonstrating that hard x-ray microscopy is a complementary method for imaging and analyzing biological samples. PMID:20349228

  19. X-ray and visible light transmission as two-dimensional, full-field moisture-sensing techniques: A preliminary comparison

    International Nuclear Information System (INIS)

    Tidwell, V.C.; Glass, R.J.

    1992-01-01

    Two independent high-resolution moisture-sensing techniques, x-ray absorption and light transmission, have been developed for use in two-dimensional, thin-slab experimental systems. The techniques yield full-field measurement capabilities with exceptional resolution of moisture content in time and space. These techniques represent powerful tools for the experimentalist to investigate processes governing unsaturated flow and transport through fractured and nonfractured porous media. Evaluation of these techniques has been accomplished by direct comparison of data obtained by means of the x-ray and light techniques as well as comparison with data collected by gravimetric and gamma-ray densitometry techniques. Results show excellent agreement between data collected by the four moisture-content measurement techniques. This program was established to support the Yucca Mountain Site Characterization Project

  20. 3D nanoscale imaging of the yeast, Schizosaccharomyces pombe, by full-field transmission X-ray microscopy at 5.4 keV.

    Science.gov (United States)

    Chen, Jie; Yang, Yunhao; Zhang, Xiaobo; Andrews, Joy C; Pianetta, Piero; Guan, Yong; Liu, Gang; Xiong, Ying; Wu, Ziyu; Tian, Yangchao

    2010-07-01

    Three-dimensional (3D) nanoscale structures of the fission yeast, Schizosaccharomyces pombe, can be obtained by full-field transmission hard X-ray microscopy with 30 nm resolution using synchrotron radiation sources. Sample preparation is relatively simple and the samples are portable across various imaging environments, allowing for high-throughput sample screening. The yeast cells were fixed and double-stained with Reynold's lead citrate and uranyl acetate. We performed both absorption contrast and Zernike phase contrast imaging on these cells in order to test this method. The membranes, nucleus, and subcellular organelles of the cells were clearly visualized using absorption contrast mode. The X-ray images of the cells could be used to study the spatial distributions of the organelles in the cells. These results show unique structural information, demonstrating that hard X-ray microscopy is a complementary method for imaging and analyzing biological samples.