Two forms of acid alpha-D-mannosidase in monkey brain: evidence for the co-existence of high mannose and complex oligosaccharides in one form.

Science.gov (United States)

Mathur, R; Alvares, K; Balasubramanian, A S

1984-09-28

Lysosomal alpha-D-mannosidase of monkey brain existed in two forms. One form of mannosidase was bound to the Ricinus communis agglutinin120 (RCA1)-Sepharose and could be specifically eluted with lactose. The other form did not bind to the RCA1-Sepharose. Both forms of mannosidase could bind to a similar extent to the immobilized brain lysosomal receptor protein. Both the forms were purified to apparent homogeneity. Neutral sugar analysis by GLC showed the presence of glucose, mannose and galactose in the RCA1-Sepharose bindable mannosidase and glucose and mannose in the non-bindable mannosidase. Several other brain lysosomal hydrolases did not bind to the RCA1-Sepharose. The results suggested the existence of only high mannose oligosaccharides in the RCA1 non-bindable mannosidase and both high mannose and complex oligosaccharides in the bindable mannosidase.

CONSIDERAÇÕES ACERCA DA FICIONALIDADE E DA DIMENSÃO ARGUMENTATIVA EM “DOM CASMURRO”

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Cristia Rodrigues Miranda

2013-12-01

Full Text Available This study aims to analyze, from the rhetorical perspective discourse discursive and argumentative present in Don Casmurro. To do so, left with the hypothesis that the narrative discourse of Bento, character-narrador, suggests a question that crystallized at the reception and points to the question about thesis: “Capitu cheated or not Bento?” To analyze these effects were useful in Mendes (2011 and (2004, studies on the fictionally. Perelman and Olbrechts-Tyteca (2005, Amossy (2011 and Aristotle (2008 helped us to analyze the size argumentative and rhetorical categorical supposedly present in the work. As the result the analysis pointed to an unfolding and dialogism in rethorical that turns accuser charged, ie, narrator and narrate defendand in court. All this narrative game would only be possible through the contract ficcional and argumentative dimension language.

Chemical-mineralogical characterisation of coarse recycled concrete aggregate

International Nuclear Information System (INIS)

Limbachiya, M.C.; Marrocchino, E.; Koulouris, A.

2007-01-01

The construction industry is now putting greater emphasis than ever before on increasing recycling and promoting more sustainable waste management practices. In keeping with this approach, many sectors of the industry have actively sought to encourage the use of recycled concrete aggregate (RCA) as an alternative to primary aggregates in concrete production. The results of a laboratory experimental programme aimed at establishing chemical and mineralogical characteristics of coarse RCA and its likely influence on concrete performance are reported in this paper. Commercially produced coarse RCA and natural aggregates (16-4 mm size fraction) were tested. Results of X-ray fluorescence (XRF) analyses showed that original source of RCA had a negligible effect on the major elements and a comparable chemical composition between recycled and natural aggregates. X-ray diffraction (XRD) analyses results indicated the presence of calcite, portlandite and minor peaks of muscovite/illite in recycled aggregates, although they were directly proportioned to their original composition. The influence of 30%, 50%, and 100% coarse RCA on the chemical composition of equal design strength concrete has been established, and its suitability for use in a concrete application has been assessed. In this work, coarse RCA was used as a direct replacement for natural gravel in concrete production. Test results indicated that up to 30% coarse RCA had no effect on the main three oxides (SiO 2 , Al 2 O 3 and CaO) of concrete, but thereafter there was a marginal decrease in SiO 2 and increase in Al 2 O 3 and CaO contents with increase in RCA content in the mix, reflecting the original constituent's composition

Chemical-mineralogical characterisation of coarse recycled concrete aggregate.

Science.gov (United States)

Limbachiya, M C; Marrocchino, E; Koulouris, A

2007-01-01

The construction industry is now putting greater emphasis than ever before on increasing recycling and promoting more sustainable waste management practices. In keeping with this approach, many sectors of the industry have actively sought to encourage the use of recycled concrete aggregate (RCA) as an alternative to primary aggregates in concrete production. The results of a laboratory experimental programme aimed at establishing chemical and mineralogical characteristics of coarse RCA and its likely influence on concrete performance are reported in this paper. Commercially produced coarse RCA and natural aggregates (16-4 mm size fraction) were tested. Results of X-ray fluorescence (XRF) analyses showed that original source of RCA had a negligible effect on the major elements and a comparable chemical composition between recycled and natural aggregates. X-ray diffraction (XRD) analyses results indicated the presence of calcite, portlandite and minor peaks of muscovite/illite in recycled aggregates, although they were directly proportioned to their original composition. The influence of 30%, 50%, and 100% coarse RCA on the chemical composition of equal design strength concrete has been established, and its suitability for use in a concrete application has been assessed. In this work, coarse RCA was used as a direct replacement for natural gravel in concrete production. Test results indicated that up to 30% coarse RCA had no effect on the main three oxides (SiO2, Al2O3 and CaO) of concrete, but thereafter there was a marginal decrease in SiO2 and increase in Al2O3 and CaO contents with increase in RCA content in the mix, reflecting the original constituent's composition.

Rolling circle amplification of metazoan mitochondrialgenomes

Energy Technology Data Exchange (ETDEWEB)

Simison, W. Brian; Lindberg, D.R.; Boore, J.L.

2005-07-31

Here we report the successful use of rolling circle amplification (RCA) for the amplification of complete metazoan mt genomes to make a product that is amenable to high-throughput genome sequencing techniques. The benefits of RCA over PCR are many and with further development and refinement of RCA, the sequencing of organellar genomics will require far less time and effort than current long PCR approaches.

16-slice multi-detector row CT coronary angiography: image quality and optimization of the image reconstruction window

International Nuclear Information System (INIS)

Kim, Yoo Kyung; Shim, Sung Shine; Lim, Soo Mee; Hwang, Ji Young; Kim, Yoon Kyung

2005-01-01

The purpose of this experiment is to investigate the image quality of CT coronary angiography using a 16-slice multi-detector row CT and to determine the optimal image reconstruction window. CT coronary angiography was obtained in 36 nonsymptomatic volunteers using a 16-slice multi-detector row CT (SOMATOM Sensation, Siemens Medical System). The mean heart rates were 70 beats per minute (bpm) or less in 18 persons and more than 70 bpm in 18 persons. Eleven data sets were obtained for each patient (reconstructed at 30%-80% of the cardiac cycle with an increment of 5%). Image quality of the eight coronary segments [left main coronary artery (LM), proximal and middle segments of left anterior descending artery (p-LAD, m-LAN) and left circumflex coronary artery (p-LCx, m-LCx) and proximal, middle and distal segments of right coronary artery (p-RCA, m-RCA, d-RCA)] was assessed. The optimal reconstruction windows in the cardiac cycle for the best image quality were 60-70% for the segments of the LM, LAD, and LC arteries in two groups (bpm 70) and 55-65% (bpm 70) for the segments of the RCA. On the best dataset for each coronary segment, the following diagnostic image quality was achieved in the two groups: LM: 100%, 83%; p-LAD: 100%, 88% m-LAD: 100%, 72%; p-LCx: 100%, 72%; m-LCx: 100%, 72%; p-RCA: 94%, 72%; m-RCA: 61%, 50%; d-RCA: 100%, 80%. The 16 slice multi-detector row CT scan provided visualization of the coronary arteries with high resolution. Especially in the group with a mean heart rate of 70 bpm or less, all the coronary segments except the RCA showed diagnostic image quality. Optimal image quality was achieved with a 60-70% trigger delay for all coronary arterial segments, but the best images of RCA were achieved in the earlier cardiac phase in the patients with a mean heart rate of more than 70 bpm

PENGURANGAN DEFECT PADA PRODUK SEPATU DENGAN MENGINTEGRASIKAN STATISTICAL PROCESS CONTROL (SPC DAN ROOT CAUSE ANALYSIS (RCA STUDI KASUS PT. XYZ

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Moch. Teguh Fajrin

2018-04-01

Full Text Available PT. XYZ is a foreign capital investment companies are located in one area of town of Sidoarjo which has more than 7000 employees in it and of course want to have a high quality product . PT footwear products. XYZ is the world quality products that promote the quality and comfort of the wearer. Problems that occur in the production process of PT . XYZ of 7 -injection engine that has the most number of engine defect is 5.6 and 7. Quality products at heavily influence the shoe production to consumers. If damaged, then the product can not be distributed to consumers .Therefore , the quality of the shoes must be maintained for the successful marketing of the product. From our previous improvements made in reducing the defect in the production process , but the result is less than optimal , so do research that aims to make improvements again with another method . The method used in this research is to apply the methods of Statistical Processing Control (SPC and Root Cause Analysis (RCA. The results of the check sheet analysis and Pareto diagram can be seen the frequency of product defects (defects over roughing most occurred in March 2016 as many as 345 shoes (62% of the total production of 489 products. Then the second frequency in February 2016 as many as 214 shoes (38% of the total production of 357 products. And from the image Control Chart P can be concluded that the data are in a state of uncontrolled. Because of all these 50 data, there is one data point that is outside the control limits (out of control, on the 4th point the data has a value of the proportion of 1, beyond the limits Upper Control Limit (UCL is equal to 0.938. During the dots located within the boundaries of a controller, a process is under controlled conditions, and no action required. However, one point that lies outside the control limit is interpreted as the fact that the quality control in the production process (injection PT. XYZ uncontrolled or still experiencing

Molecular and biochemical characterization of carbonic anhydrases of Paracoccidioides.

Science.gov (United States)

Tomazett, Mariana Vieira; Zanoelo, Fabiana Fonseca; Bailão, Elisa Flávia Cardoso; Bailão, Alexandre Melo; Borges, Clayton Luiz; Soares, Célia Maria de Almeida

2016-01-01

Carbonic anhydrases (CA) belong to the family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide to bicarbonate. In the present work, we characterized the cDNAs of four Paracoccidioides CAs (CA1, CA2, CA3, and CA4). In the presence of CO2, there was not a significant increase in fungal ca1, ca2 and ca4 gene expression. The ca1 transcript was induced during the mycelium-to-yeast transition, while ca2 and ca4 gene expression was much higher in yeast cells, when compared to mycelium and mycelium-to-yeast transition. The ca1 transcript was induced in yeast cells recovered directly from liver and spleen of infected mice, while transcripts for ca2 and ca4 were down-regulated. Recombinant CA1 (rCA1) and CA4 (rCA4), with 33 kDa and 32 kDa respectively, were obtained from bacteria. The enzymes rCA1 (β-class) and rCA4 (α-class) were characterized regarding pH, temperature, ions and amino acids addition influence. Both enzymes were stable at pHs 7.5-8.5 and temperatures of 30-35 °C. The enzymes were dramatically inhibited by Hg+2 and activated by Zn+2, while only rCA4 was stimulated by Fe2+. Among the amino acids tested (all in L configuration), arginine, lysine, tryptophan and histidine enhanced residual activity of rCA1 and rCA4.

Mercúrio total em cabelos: uma contribuição para se avaliar o nível de exposição em Poconé, Mato Grosso, Brasil Total mercury in hair: a contribution to the evaluation of mercury exposure levels in Poconé, Mato Grosso, Brazil

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Flávia Nogueira

1997-10-01

Full Text Available Ocorrem na Bacia do Rio Bento Gomes (MT, às margens do Pantanal Mato-grossense, cerca de sessenta garimpos de ouro, onde o mercúrio é utilizado de forma intensiva nos processos de produção, através da formação de amálgamas que facilitam a aglutinação de partículas finas. A queima do amálgama nem sempre é feita em sistemas fechados de recuperação, havendo, portanto, perda de vapor para a atmosfera. Este estudo traz resultados de análises de mercúrio total nos cabelos de quatro grupos de voluntários que vivem em Poconé (MT, e faz uma caracterização geral do ambiente no que se refere à presença do metal na água e no sedimento do Rio Bento Gomes. Um equipamento de detecção por fluorescência foi usado para a determinação das concentrações, e os resultados indicam que os valores são mais baixos do que os de outras populações de áreas de garimpo no Brasil. Indicam também que a via ocupacional parece ser a mais eficiente rota potencial de contaminação da população por mercúrio.There are some 60 gold-mining sites in the Bento Gomes River basin (Mato Grosso, at the border of the Mato Grosso Pantanal (Swamp, where mercury is used to agglutinate fine gold particles through amalgamation. During burning of the amalgam to release the gold, mercury vapor is lost to the atmosphere, since closed systems for mercury recovery are not always used. This study shows the results of total mercury analysis in hair from four volunteer groups living in Poconé, Mato Grosso, and presents a general environmental description pertaining to the presence of mercury in water and sediments from the Bento Gomes River. Atomic fluorescence was used for measuring mercury concentrations. The results were lower than for other populations from gold-mining areas in Brazil.

Controlled Microwave Heating Accelerates Rolling Circle Amplification.

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Takeo Yoshimura

Full Text Available Rolling circle amplification (RCA generates single-stranded DNAs or RNA, and the diverse applications of this isothermal technique range from the sensitive detection of nucleic acids to analysis of single nucleotide polymorphisms. Microwave chemistry is widely applied to increase reaction rate as well as product yield and purity. The objectives of the present research were to apply microwave heating to RCA and indicate factors that contribute to the microwave selective heating effect. The microwave reaction temperature was strictly controlled using a microwave applicator optimized for enzymatic-scale reactions. Here, we showed that microwave-assisted RCA reactions catalyzed by either of the four thermostable DNA polymerases were accelerated over 4-folds compared with conventional RCA. Furthermore, the temperatures of the individual buffer components were specifically influenced by microwave heating. We concluded that microwave heating accelerated isothermal RCA of DNA because of the differential heating mechanisms of microwaves on the temperatures of reaction components, although the overall reaction temperatures were the same.

Controlled Microwave Heating Accelerates Rolling Circle Amplification.

Science.gov (United States)

Yoshimura, Takeo; Suzuki, Takamasa; Mineki, Shigeru; Ohuchi, Shokichi

2015-01-01

Rolling circle amplification (RCA) generates single-stranded DNAs or RNA, and the diverse applications of this isothermal technique range from the sensitive detection of nucleic acids to analysis of single nucleotide polymorphisms. Microwave chemistry is widely applied to increase reaction rate as well as product yield and purity. The objectives of the present research were to apply microwave heating to RCA and indicate factors that contribute to the microwave selective heating effect. The microwave reaction temperature was strictly controlled using a microwave applicator optimized for enzymatic-scale reactions. Here, we showed that microwave-assisted RCA reactions catalyzed by either of the four thermostable DNA polymerases were accelerated over 4-folds compared with conventional RCA. Furthermore, the temperatures of the individual buffer components were specifically influenced by microwave heating. We concluded that microwave heating accelerated isothermal RCA of DNA because of the differential heating mechanisms of microwaves on the temperatures of reaction components, although the overall reaction temperatures were the same.

A invenção das categorias travesti e transexual no discurso científico

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Melissa Barbieri de Oliveira

2014-05-01

Full Text Available LEITE JR., Jorge. Apresentação: Berenice Bento. Nossos corpos também mudam: a invenção das categorias “travesti” e “transexual” no discurso científico. São Paulo: Annablume, 2011. 240 p.

Furosemide-131I-hippuran renography after angiotensin-converting enzyme inhibition for the diagnosis of renovascular hypertension

International Nuclear Information System (INIS)

Erbsloeh-Moeller, B.Du.; Dumas, A.; Roth, D.; Sfakianakis, G.N.; Bourgoignie, J.J.

1991-01-01

We have previously demonstrated the greater sensitivity of 131I-hippuran renography than 99mTC-DTPA scintigraphy to diagnose renovascular hypertension (RVH). This study assesses the predictive diagnostic value of furosemide-131I-hippuran renography after angiotensin-converting enzyme (ACE) inhibition in patients with and without RVH. All patients were investigated at the University of Miami/Jackson Memorial Medical Center. Twenty-eight patients had RVH and 22 did not. Twenty-eight patients had normal or minimally decreased renal function and 22 had renal insufficiency. Renography was performed 60 minutes after oral administration of 50 mg captopril or 10 minutes after intravenous injection of 40 micrograms/kg enalaprilat. Forty milligrams of furosemide were administered intravenously 2 minutes after injection of 131I-hippuran. The residual cortical activity (RCA) of 131I-hippuran was measured at 20 minutes. RVH was unlikely when RCA after ACE inhibition was less than 30% of peak cortical activity. Conversely, RVH was present when 131I-hippuran cortical activity steadily increased throughout the test to reach 100% at 20 minutes. In azotemic patients with RCA between 31% and 100%, RVH was differentiated from intrinsic renal disease by obtaining a baseline renogram without ACE inhibition and comparing RCA in that study and RCA after ACE inhibition. If RCA increased (indicating worsening renal function) after ACE inhibition, RVH was likely; whereas, intrinsic renal disease was more likely if RCA remained unchanged or decreased (indicating improved renal function) with ACE inhibition. The test had a specificity of 95% and a sensitivity of 96% in this population. There was a direct correlation between the results of angioplasty or surgery on high blood pressure and the changes in RCA before and after intervention (n = 20)

Furosemide- sup 131 I-hippuran renography after angiotensin-converting enzyme inhibition for the diagnosis of renovascular hypertension

Energy Technology Data Exchange (ETDEWEB)

Erbsloeh-Moeller, B.Du.; Dumas, A.; Roth, D.; Sfakianakis, G.N.; Bourgoignie, J.J. (Univ. of Miami/Jackson Memorial Medical Center, FL (USA))

1991-01-01

We have previously demonstrated the greater sensitivity of 131I-hippuran renography than 99mTC-DTPA scintigraphy to diagnose renovascular hypertension (RVH). This study assesses the predictive diagnostic value of furosemide-131I-hippuran renography after angiotensin-converting enzyme (ACE) inhibition in patients with and without RVH. All patients were investigated at the University of Miami/Jackson Memorial Medical Center. Twenty-eight patients had RVH and 22 did not. Twenty-eight patients had normal or minimally decreased renal function and 22 had renal insufficiency. Renography was performed 60 minutes after oral administration of 50 mg captopril or 10 minutes after intravenous injection of 40 micrograms/kg enalaprilat. Forty milligrams of furosemide were administered intravenously 2 minutes after injection of 131I-hippuran. The residual cortical activity (RCA) of 131I-hippuran was measured at 20 minutes. RVH was unlikely when RCA after ACE inhibition was less than 30% of peak cortical activity. Conversely, RVH was present when 131I-hippuran cortical activity steadily increased throughout the test to reach 100% at 20 minutes. In azotemic patients with RCA between 31% and 100%, RVH was differentiated from intrinsic renal disease by obtaining a baseline renogram without ACE inhibition and comparing RCA in that study and RCA after ACE inhibition. If RCA increased (indicating worsening renal function) after ACE inhibition, RVH was likely; whereas, intrinsic renal disease was more likely if RCA remained unchanged or decreased (indicating improved renal function) with ACE inhibition. The test had a specificity of 95% and a sensitivity of 96% in this population. There was a direct correlation between the results of angioplasty or surgery on high blood pressure and the changes in RCA before and after intervention (n = 20).

3-D Imaging using Row--Column-Addressed 2-D Arrays with a Diverging Lens

DEFF Research Database (Denmark)

Bouzari, Hamed; Engholm, Mathias; Stuart, Matthias Bo

2016-01-01

It has been shown that row–column-addressed (RCA) 2-D arrays can be an inexpensive alternative to fully addressed 2-D arrays. Generally imaging with an RCA 2-D array is limited to its forward-looking volume region. Constructing a double-curved RCA 2-D array or applying a diverging lens over......, is designed for imaging down to 14 cm at a volume rate of 88 Hz. The curvilinear imaging performance of a λ/2-pitch 3 MHz 62+62 RCA 2-D array is investigated as a function of depth, using a diverging lens with f-number of -1. The results of this study demonstrate that the proposed beamforming approach...

A new member of a family of ATPases is essential for assembly of mitochondrial respiratory chain and ATP synthetase complexes in Saccharomyces cerevisiae.

Science.gov (United States)

Tzagoloff, A; Yue, J; Jang, J; Paul, M F

1994-10-21

Respiration-defective pet mutants of Saccharomyces cerevisiae, assigned to complementation group G25, are grossly deficient in mitochondrial respiratory and ATPase complexes. This phenotype is usually found in strains impaired in mitochondrial protein synthesis. The G25 mutants, however, synthesize all of the proteins encoded by mitochondrial DNA. The mutants are also able to import and process cytoplasmically derived subunits of these enzymes. These results are most compatible with the idea that the gene defined by G25 mutants (RCA1) codes for a protein essential for the assembly of functional respiratory and ATPase complexes. The RCA1 gene has been cloned by complementation of an rca1 mutant with a yeast genomic library. The sequence of the encoded product shows Rca1 protein to be a new member of a recently described family of ATPases. The Rca1 protein is a mitochondrial membrane protein and is the third known member of this family implicated to function in the biogenesis of mitochondria. The primary structure of Rca1 protein indicates several distinct domains in addition to the common purine nucleotide binding region shared by all members of this protein family. One, located in the amino-terminal half, contains two hydrophobic stretches of sufficient length to span a membrane lipid bilayer.

Compressive strength and resistance to chloride ion penetration and carbonation of recycled aggregate concrete with varying amount of fly ash and fine recycled aggregate.

Science.gov (United States)

Sim, Jongsung; Park, Cheolwoo

2011-11-01

Construction and demolition waste has been dramatically increased in the last decade, and social and environmental concerns on the recycling have consequently been increased. Recent technology has greatly improved the recycling process for waste concrete. This study investigates the fundamental characteristics of concrete using recycled concrete aggregate (RCA) for its application to structural concrete members. The specimens used 100% coarse RCA, various replacement levels of natural aggregate with fine RCA, and several levels of fly ash addition. Compressive strength of mortar and concrete which used RCA gradually decreased as the amount of the recycled materials increased. Regardless of curing conditions and fly ash addition, the 28 days strength of the recycled aggregate concrete was greater than the design strength, 40 MPa, with a complete replacement of coarse aggregate and a replacement level of natural fine aggregate by fine RCA up to 60%. The recycled aggregate concrete achieved sufficient resistance to the chloride ion penetration. The measured carbonation depth did not indicate a clear relationship to the fine RCA replacement ratio but the recycled aggregate concrete could also attain adequate carbonation resistance. Based on the results from the experimental investigations, it is believed that the recycled aggregate concrete can be successfully applied to structural concrete members. Copyright © 2011 Elsevier Ltd. All rights reserved.

Molecular and biochemical characterization of carbonic anhydrases of Paracoccidioides

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Mariana Vieira Tomazett

Full Text Available Abstract Carbonic anhydrases (CA belong to the family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide to bicarbonate. In the present work, we characterized the cDNAs of four Paracoccidioides CAs (CA1, CA2, CA3, and CA4. In the presence of CO2, there was not a significant increase in fungal ca1, ca2 and ca4 gene expression. The ca1 transcript was induced during the mycelium-to-yeast transition, while ca2 and ca4 gene expression was much higher in yeast cells, when compared to mycelium and mycelium-to-yeast transition. The ca1 transcript was induced in yeast cells recovered directly from liver and spleen of infected mice, while transcripts for ca2 and ca4 were down-regulated. Recombinant CA1 (rCA1 and CA4 (rCA4, with 33 kDa and 32 kDa respectively, were obtained from bacteria. The enzymes rCA1 (β-class and rCA4 (α-class were characterized regarding pH, temperature, ions and amino acids addition influence. Both enzymes were stable at pHs 7.5-8.5 and temperatures of 30-35 °C. The enzymes were dramatically inhibited by Hg+2 and activated by Zn+2, while only rCA4 was stimulated by Fe2+. Among the amino acids tested (all in L configuration, arginine, lysine, tryptophan and histidine enhanced residual activity of rCA1 and rCA4.

Simultaneous localization of an hepatic binding protein specific for galactose and of galactose-containing receptors on rat hepatocytes.

Science.gov (United States)

Horisberger, M; VonLanthen, M

1978-11-01

The hepatic binding protein, specific for galactose-terminated glycoproteins (asialoglycoproteins) and the receptors for the Ricinus communis lectin, specific for galactose residues (RCA1), were simultaneously localized on isolated rat hepatocytes by the gold method. The marker for the binding protein was prepared from gold granules (5 nm in diam.) labeled with ceruloplasmin and desialylated. The marker specific for galactose-containing receptors consisted of granules (17 nm in diameter) labeled with RCA1. It was established that both markers did not interact. Hepatocytes (fresh or briefly fixed with glutaraldehyde) were successively incubated with the asialoceruloplasmin and the RCA1 marker. Examination of thin sections by electron microscopy indicated that the binding protein and the RCA1 receptors were often in the proximity of each other on the plasmamembrane. Using the same technique, wheat germ agglutinin (WGA) receptors were generally found on area of the plasmamembrane poorly marked by the RCA1 gold marker. The binding of asialoceruloplasmin gold markers was studied as a function of the size of the granules. It became insignificant when the size was above 17 nm. Previous results have shown that the binding of RCA1 is low when the marker reaches 50 nm in size while WGA markers up to 75 nm are well bound by hepatocytes. It is therefore hypothesized that the binding protein and RCA1 receptors are located between glycoprotein brushes of increasing spacing while part or all of the WGA receptors are located at the periphery of the brushes.

Improving health care costing with resource consumption accounting.

Science.gov (United States)

Ozyapici, Hasan; Tanis, Veyis Naci

2016-07-11

Purpose - The purpose of this paper is to explore the differences between a traditional costing system (TCS) and resource consumption accounting (RCA) based on a case study carried out in a hospital. Design/methodology/approach - A descriptive case study was first carried out to identify the current costing system of the case hospital. An exploratory case study was then conducted to reveal how implementing RCA within the case hospital assigns costs differently to gallbladder surgeries than the current costing system (i.e. a TCS). Findings - The study showed that, in contrast to a TCS, RCA considers the unused capacity, which is the difference between the work that can be performed based on current resources and the work that is actually being performed. Therefore, it assigns lower total costs to open and laparoscopic gallbladder surgeries. The study also showed that by separating costs into fixed and variable RCA allows managers to benefit from a pricing strategy based on the difference between the service's selling price and variable costs incurred in providing that service. Research limitations/implications - The limitation of this study is that, because of time constraints, the implementation was performed in the general surgery department only. However, since RCA is an advanced system that has the same application procedures for any department inside in a hospital, managers need only time gaps to implement this system to all parts of the hospital. Practical implications - This study concluded that RCA is better than a TCS for use in health care settings that have high overhead costs because it accurately assigns overhead costs to services by considering unused capacities incurred by a hospital. Consequently, this study provides insight into both measuring and managing unused capacities within the health care sector. This study also concluded that RCA helps health care administrators increase their competitive advantage by allowing them to determine the lowest

Damage assessment for seismic response of recycled concrete filled steel tube columns

Science.gov (United States)

Huang, Yijie; Xiao, Jianzhuang; Shen, Luming

2016-09-01

A model for evaluating structural damage of recycled aggregate concrete filled steel tube (RCFST) columns under seismic effects is proposed in this paper. The proposed model takes the lateral deformation and the effect of repeated cyclic loading into account. Available test results were collected and utilized to calibrate the parameters of the proposed model. A seismic test for six RCFST columns was also performed to validate the proposed damage assessment model. The main test parameters were the recycled coarse aggregate (RCA) replacement percentage and the bond-slip property. The test results indicated that the seismic performance of the RCFST member depends on the RCA contents and their damage index increases as the RCA replacement percentage increases. It is also indicated that the damage degree of RCFST changes with the variation of the RCA replacement percentage. Finally, comparisons between the RCA contents, lateral deformation ratio and damage degree were implemented. It is suggested that an improvement procedure should be implemented in order to compensate for the performance difference between the RCFST and normal concrete filled steel tubes (CFST).

SPATIAL AND TEMPORAL DISTRIBUTION OF Concholepas Concholepas (GASTROPODA, MURICIDAE) VELIGER LARVAE IN THE INLAND SEAS OF NORTHWEST PATAGONIA.

OpenAIRE

MOLINET FLORES, CARLOS ALBERTO; MOLINET FLORES, CARLOS ALBERTO

2005-01-01

El presente estudio fue enfocado sobre la base de la hipótesis que el desarrollo larval extracapsular de C. concholepas ocurre en aguas profundas cerca del bentos y que larvas competentes de esta especie son transportadas a la superficie por mecanismos fí 124p.

Facility design to apply cover material over radioactive residue in storage silos

International Nuclear Information System (INIS)

Fekete, L.J.; Emerson, R.J. Jr.; Heckendorn, L.A.

1991-01-01

This paper discusses the BentoGrout application system designed by Parsons under contract to the US Department of Energy (DOE) for the Environmental Remedial Action (ERA) Project, Fernald Environmental Management Project (FEMP) Fernald, Ohio, as cleaned by the K-65 removal action work plan prepared by Theta Technologies, Inc. and Westinghouse Environmental Management Company of Ohio (WEMCO) with the objectives to reduce radon emissions from the silos. The paper discusses support activities undertaken to develop the design basis and design criteria for the K-65 Silos BentoGrout Covering System. The development and execution of an application demonstration program is described with presentation of the results. Also addressed is the design of the full-scale application system and the philosophy of operational control. The instrumentation and monitoring subsystems are illustrated on system schematics. The paper concludes with an evaluation of the above activities in achieving the purpose and objectives set forth in the Removal Action Work Plan

Characterization of Ricin and R. communis Agglutinin Reference Materials

Science.gov (United States)

Worbs, Sylvia; Skiba, Martin; Söderström, Martin; Rapinoja, Marja-Leena; Zeleny, Reinhard; Russmann, Heiko; Schimmel, Heinz; Vanninen, Paula; Fredriksson, Sten-Åke; Dorner, Brigitte G.

2015-01-01

Ricinus communis intoxications have been known for centuries and were attributed to the toxic protein ricin. Due to its toxicity, availability, ease of preparation, and the lack of medical countermeasures, ricin attracted interest as a potential biological warfare agent. While different technologies for ricin analysis have been established, hardly any universally agreed-upon “gold standards” are available. Expert laboratories currently use differently purified in-house materials, making any comparison of accuracy and sensitivity of different methods nearly impossible. Technically challenging is the discrimination of ricin from R. communis agglutinin (RCA120), a less toxic but highly homologous protein also contained in R. communis. Here, we established both highly pure ricin and RCA120 reference materials which were extensively characterized by gel electrophoresis, liquid chromatography-electrospray ionization-tandem mass spectrometry (LC-ESI MS/MS), and matrix-assisted laser desorption ionization–time of flight approaches as well as immunological and functional techniques. Purity reached >97% for ricin and >99% for RCA120. Different isoforms of ricin and RCA120 were identified unambiguously and distinguished by LC-ESI MS/MS. In terms of function, a real-time cytotoxicity assay showed that ricin is approximately 300-fold more toxic than RCA120. The highly pure ricin and RCA120 reference materials were used to conduct an international proficiency test. PMID:26703723

Engineering Behavior of Concrete with Recycled Aggregate

Directory of Open Access Journals (Sweden)

Ayob Afizah

2017-01-01

Full Text Available Concrete is extensively used as construction materials in Malaysia. Concrete contributes suitable feature for construction industry for instance durability, adequate compressive strength, fire resistance, availability and is economic as compared to other construction materials. Depletion of natural resources and disposal of construction and demolition waste remarkably claim environmental threat. In this paper, the engineering behavior, durability, and concrete microstructure of recycled concrete aggregates (RCA on short-term concrete properties were investigated. The studied concrete at design mix proportion of 1:0.55:2.14:2.61 (weight of cement :coarse aggregates :sand :water used to obtain medium-high compressive strength with 20%, 50%, and 100% of RCA. Results show that for the same water/cement ratio, RCA replacement up to 50% still achieved the targeted compressive strength of 25 MPa at 28 curing days. Addition, at similar RCA replacement, the highest carbonation depth value was found at 1.03 mm which could be attributed to the pozzolanic reaction, thus led to lower carbonation resistance. Scanning electron microscopy microstructure shows that the RCA surface was porous and covered with loose particles. Moreover, the interfacial transition zone was composed of numerous small pores, micro cracks, and fissures that surround the mortar matrix. On the basis of the obtained results, recommendable mineral admixtures of RCA are necessary to enhance the quality of concrete construction.

Characterization of Ricin and R. communis Agglutinin Reference Materials

Directory of Open Access Journals (Sweden)

Sylvia Worbs

2015-11-01

Full Text Available Ricinus communis intoxications have been known for centuries and were attributed to the toxic protein ricin. Due to its toxicity, availability, ease of preparation, and the lack of medical countermeasures, ricin attracted interest as a potential biological warfare agent. While different technologies for ricin analysis have been established, hardly any universally agreed-upon “gold standards” are available. Expert laboratories currently use differently purified in-house materials, making any comparison of accuracy and sensitivity of different methods nearly impossible. Technically challenging is the discrimination of ricin from R. communis agglutinin (RCA120, a less toxic but highly homologous protein also contained in R. communis. Here, we established both highly pure ricin and RCA120 reference materials which were extensively characterized by gel electrophoresis, liquid chromatography-electrospray ionization-tandem mass spectrometry (LC-ESI MS/MS, and matrix-assisted laser desorption ionization–time of flight approaches as well as immunological and functional techniques. Purity reached >97% for ricin and >99% for RCA120. Different isoforms of ricin and RCA120 were identified unambiguously and distinguished by LC-ESI MS/MS. In terms of function, a real-time cytotoxicity assay showed that ricin is approximately 300-fold more toxic than RCA120. The highly pure ricin and RCA120 reference materials were used to conduct an international proficiency test.

Improving animal productivity by supplementary feeding of multi-nutrient blocks, controlling internal parasites and enhancing utilization of alternate feed resources. A publication prepared under the framework of an RCA with technical support of the Joint FAO/IAEA Programme of Nuclear Techniques in Food and Agriculture

International Nuclear Information System (INIS)

2006-12-01

countries generally encounter another principal constraint: health. Of the health constraints, bacterial and viral diseases can be successfully controlled through conventional vaccination and quarantine procedures. However, for parasitic disease, these approaches are either not yet possible or impractical, and chemotherapy, coupled with grazing management, are the only methods of control method currently available. In developing countries, the losses induced by clinical and subclinical parasite infections have been estimated to equal the value of the present output of ruminant industries, therefore improved control has the potential to yield considerable productivity benefits. The RCA (Regional Cooperation Agreement for the Asia and Pacific Region) project, RAS/5/035 entitled Improving Animal Productivity and Reproductive Efficiency was initiated in 1999 to assist RCA Member States to improve animal productivity and reproductive efficiency. This project had two components: animal nutrition, and animal reproduction. The animal nutrition component focused on: (i) developing and feeding of urea-molasses multinutrient blocks to supply nutrients deficient in crop residues and forages; (ii) using the ureamolasses multinitrient blocks for the delivery of anthelmintic medication to control gastrointestinal nematode parasitism; and (iii) enhancing efficiency of utilization of feed resources which are locally available and for which humans are not competing with livestock for food. The present publication presents results on these three aspects obtained by the participating groups from the RCA Member States and presented at the Final Review Meeting of the project held in October 2004 in Bangkok, Thailand. This publication is a good source of reference for research workers, students and extension workers alike. It will help promote efficient utilization of feed resources and enhance animal productivity to meet the challenges imposed by the 'Livestock Revolution' taking place in

Characteristics of Recycled Concrete Aggregates from Precast Slab Block Buildings

Science.gov (United States)

Venkrbec, Václav; Nováková, Iveta; Henková, Svatava

2017-10-01

Precast slab block buildings (PSBB) typically and frequently occur in Central and Eastern Europe, as well as elsewhere in the world. Some of these buildings are currently used beyond their service life capacity. The utilization of recycled materials from these buildings with regard to applying the principles of sustainable construction and using recycled materials will probably be significant in the following years. Documentation from the manufacturing processes of prefabricated blocks for precast slab block buildings is not available, and also it is difficult to declare technological discipline during the construction of these buildings. Therefore, properties of recycled concrete aggregates (RCA) produced from construction and demolition waste (C&DW) of precast slab block buildings build between 1950s to 1990s are not sufficiently known. The demolition of these buildings is very rare today, but it can be assumed an increase in demolitions of these buildings in the future. The use of RCA in new concrete requires verification/testing of the geometrical and physical properties of RCA according to the EN 12 620+A1 standard. The aim of the contribution is to present a case study of the demolition of slab block building with emphasis on RCA usage. The paper presents the results of the tests according to European standards for determining selected geometrical and physical properties of the RCA. The paper describes and evaluates tests such as determination of particle size distribution - Sieve Analysis, content of fine particles, determination of density and water absorption. The results of the properties testing of RCA are compared with the properties of natural aggregate. The general boundary conditions of RCA particular tests are presented.

Myocardial ischemia due to compression of an unruptured thoracic aortic aneurysm in a patient with Marfan syndrome.

Science.gov (United States)

Minami, Hiroya; Asada, Tatsuro; Gan, Kunio; Abe, Koichiro; Izumi, Satoshi

2007-06-01

We report a 33-year-old woman who had a 60-mm thoracic aneurysm of the ascending aorta with Marfan syndrome and effort angina due to compression of the right coronary artery (RCA) by the aneurysm. Surgery was performed using the Bentall procedure and a coronary artery bypass graft to the RCA. Postoperatively, coronary angiography showed that the coronary flow of the RCA was restored by removing the aneurysmal compression. The patient was discharged without angina on postoperative day 21.

Frayed careers: exploring rhythms of working lives

NARCIS (Netherlands)

Sabelis, I.H.J.; Schilling, E.

2013-01-01

In studies on difference related to age and gender, we face 'abnormal' or 'typical' work-life arrangements vis-à-vis taken-for-granted career concepts. Age and career are conceptualized from different angles depending on politics of work and organization, societal perspectives of age group position,

Effect of curd washing on the properties of reduced-calcium and standard-calcium Cheddar cheese.

Science.gov (United States)

Hou, Jia; McSweeney, Paul L H; Beresford, Thomas P; Guinee, Timothy P

2014-10-01

Washed (W) and nonwashed (NW) variants of standard (SCa) and reduced-calcium (RCa) Cheddar cheeses were made in triplicate, ripened for a 270-d period, and analyzed for composition and changes during maturation. Curd washing was applied to cheeses to give a target level of lactose plus lactic acid in cheese moisture of 3.9 g/100 g in the W cheese, compared with a value of 5.3 g/100 g of lactose plus lactic acid in cheese moisture in the control NW cheeses. The 4 cheese types were denoted standard calcium nonwashed (SCaNW), standard calcium washed (SCaW), reduced-calcium nonwashed (RCaNW), and reduced-calcium washed (RCaW). The mean calcium level was 760 mg/100 g in the SCaNW and SCaW and 660 mg/100 g in the RCaNW and RCaW cheeses. Otherwise the gross composition of all cheeses was similar, each with protein, fat, and moisture levels of ~26, 32, and 36 g/100 g, respectively. Curd washing significantly reduced the mean level of lactic acid in the SCaW cheese and residual lactose in both SCaW and RCaW cheeses. The mean pH of the standard-calcium cheese over the 270-d ripening period increased significantly with curd washing and ripening time, in contrast to the reduced-calcium cheese, which was not affected by the latter parameters. Otherwise curd washing had little effect on changes in populations of starter bacteria or nonstarter lactic acid bacteria, proteolysis, rheology, or color of the cheese during ripening. Descriptive sensory analysis at 270 d indicated that the SCaW cheese had a nuttier, sweeter, less fruity, and less rancid taste than the corresponding SCaNW cheese. In contrast, curd washing was not as effective in discriminating between the RCaW and RCaNW cheeses. The RCaW cheese had a more buttery, caramel odor and flavor, and a more bitter, less sweet, and nutty taste than the SCaW cheese, whereas the RCaNW had a more pungent and less fruity flavor, a less fruity odor, a saltier, more-bitter, and less acidic taste, and a more astringent mouthfeel than

DAYA SAING EKSPOR TUNA KALENG INDONESIA DI UNI EROPA TAHUN 2003-2013

Directory of Open Access Journals (Sweden)

Umar Wahono

2017-06-01

Full Text Available Perbedaan tarif yang diberikan antara Indonesia yang lebih tinggi sebesar 20.5% dibandingkan dengan negara pesaing utamanya yang tergabung dalang Africa, Caribbean, Pasific (ACP Countries dengan pelayanan tarif impor hingga 0% ke pasar Uni Eropa (UE. Keadaan ini mampu menyebabkan menghilangnya distorsi perbedaan harga sesungguhnya yang seharusnya menjadi keuntungan lebih atas keunggulan komparatif yang dimiliki. Hal ini mampu melemahkan daya saing komoditi ekspor akibat dampak kenaikan harga terhadap tarif. Penelitian ini bertujuan untuk gambaran daya saing komoditas tuna kaleng Indonesia terhadap negara pesaingnya dipasar UE pada periode 2003-2013. Metode yang digunakan dalam penelitin ini adalah metode Revealed Comparative Advantage (RCA yang kemudian nilai RCA dikomparasikan tiap-tiap negara pengekspor utama tuna kaleng di pasar UE untuk melihat posisi daya saing relatifnya. Sedangkan untuk mendekomposisikan determinan pertumbuhan ekspor tuna kaleng Indonesia ke UE digunankan metode Constant Market Share (CMS. Hasil perhitungan nilai RCA tuna kaleng Indonesia periode 2003-2013 di pasar UE memiliki daya saing dengan rata-rata nilai RCA 4.27. Namun masih dibawah rata-rata nilai RCA negara ACP Countries. Perbedaan pelayanan tarif impor oleh UE untuk komoditas tuna kaleng Indonesia tidak berdampak terhadap penurunan daya saing. The difference between the rates given Indonesia which is higher by 20.5% compared to its main competitor countries that joined the mastermind Africa, Caribbean, Pacific (ACP Countries with service import tariffs to 0% to the European Union (EU. This situation is capable of causing the disappearance of the distortion of the true price difference should be more advantages over comparative advantage. It is capable of undermining the competitiveness of export commodities due to the impact of price increases on tariffs. This study aims to illustrate the competitiveness of commodities Indonesian canned tuna to the EU market of

Steam-deformed Judkins-left guiding catheter with use of the GuideLiner(®) catheter to deliver stents for anomalous right coronary artery.

Science.gov (United States)

Kuno, Toshiki; Fujisawa, Taishi; Yamazaki, Hiroyuki; Motoda, Hiroyuki; Kodaira, Masaki; Numasawa, Yohei

2015-01-01

Percutaneous coronary intervention for anomalous right coronary artery (RCA) originating from the left coronary cusp is challenging because of our current inability to coaxially engage the guiding catheter. We report a case of an 88-year-old woman with non-ST segment elevation myocardial infarction, with an anomalous RCA origin. Using either the Judkins-Left catheter or Amplatz-Left catheter was difficult because of RCA ostium tortuosity. Thus, we used steam to deform the Judkins-Left catheter, but back-up support was insufficient to deliver the stent. We used GuideLiner®, a novel pediatric catheter with rapid exchange/monorail systems, to enhance back-up support. We were able to successfully stent with both the deformed Judkins-Left guiding catheter and GuideLiner® for an anomalous RCA origin.

Efficient use of recycled concrete in transportation infrastructure

Science.gov (United States)

2011-01-21

This study examined current national and international practices regarding the use of recycled concrete aggregates (RCA) as engineering materials by the transportation industry as well as a history of Michigan's experience with RCA. In the laboratory...

Simple engineering design for complex thermoelectric generators based on reduced current approach

DEFF Research Database (Denmark)

Wijesooriyage, Waruna Dissanayaka; Rezaniakolaei, Alireza; Rosendahl, Lasse

2015-01-01

Thermoelectric generators (TEGs) are niche candidate for the field of energy management as electrical generator devices. Generally, comprehensive and accurate design techniques for TEGs (thermoelectric generators), such as reduced current approach (RCA), are complex and time consuming processes....... This study develops a simple, comprehensive and accurate TEG designing technique based on RCA. The proposed method can predict the most efficient TEG architecture with more than 97% accuracy comparing to the RCA over wide range of possible temperature and zT for present TEG applications. Moreover...

Sequence-Dependent Mechanism of DNA Oligonucleotide Dehybridization Resolved through Infrared Spectroscopy.

Science.gov (United States)

Sanstead, Paul J; Stevenson, Paul; Tokmakoff, Andrei

2016-09-14

Despite its important role in biology and nanotechnology, many questions remain regarding the molecular mechanism and dynamics by which oligonucleotides recognize and hybridize to their complementary sequence. The thermodynamics and kinetics of DNA oligonucleotide hybridization and dehybridization are often assumed to involve an all-or-nothing two-state dissociation pathway, but deviations from this behavior can be considerable even for short sequences. We introduce a new strategy to characterize the base-pair-specific thermal dissociation mechanism of DNA oligonucleotides through steady-state and time-resolved infrared spectroscopy. Experiments are interpreted with a lattice model to provide a structure-specific interpretation. This method is applied to a model set of self-complementary 10-base-pair sequences in which the placement of GC base pairs is varied in an otherwise AT strand. Through a combination of Fourier transform infrared and two-dimensional infrared spectroscopy, experiments reveal varying degrees of deviation from simple two-state behavior. As the temperature is increased, duplexes dissociate through a path in which the terminal bases fray, without any significant contribution from loop configurations. Transient temperature jump experiments reveal time scales of 70-100 ns for fraying and 10-30 μs for complete dissociation near the melting temperature. Whether or not frayed states are metastable intermediates or short-lived configurations during the full dissociation of the duplex is dictated by the nucleobase sequence.

Laboratory evaluation of recycled concrete as aggregate in new concrete pavements.

Science.gov (United States)

2014-09-01

The Washington State Department of Transportation (WSDOT) has initiated a research project to investigate the use of recycled concrete as : aggregates (RCA) in Portland (hydraulic) cement concrete pavements (PCCP). The planned source for the RCA in t...

Retrospective cost adaptive Reynolds-averaged Navier-Stokes k-ω model for data-driven unsteady turbulent simulations

Science.gov (United States)

Li, Zhiyong; Hoagg, Jesse B.; Martin, Alexandre; Bailey, Sean C. C.

2018-03-01

This paper presents a data-driven computational model for simulating unsteady turbulent flows, where sparse measurement data is available. The model uses the retrospective cost adaptation (RCA) algorithm to automatically adjust the closure coefficients of the Reynolds-averaged Navier-Stokes (RANS) k- ω turbulence equations to improve agreement between the simulated flow and the measurements. The RCA-RANS k- ω model is verified for steady flow using a pipe-flow test case and for unsteady flow using a surface-mounted-cube test case. Measurements used for adaptation of the verification cases are obtained from baseline simulations with known closure coefficients. These verification test cases demonstrate that the RCA-RANS k- ω model can successfully adapt the closure coefficients to improve agreement between the simulated flow field and a set of sparse flow-field measurements. Furthermore, the RCA-RANS k- ω model improves agreement between the simulated flow and the baseline flow at locations at which measurements do not exist. The RCA-RANS k- ω model is also validated with experimental data from 2 test cases: steady pipe flow, and unsteady flow past a square cylinder. In both test cases, the adaptation improves agreement with experimental data in comparison to the results from a non-adaptive RANS k- ω model that uses the standard values of the k- ω closure coefficients. For the steady pipe flow, adaptation is driven by mean stream-wise velocity measurements at 24 locations along the pipe radius. The RCA-RANS k- ω model reduces the average velocity error at these locations by over 35%. For the unsteady flow over a square cylinder, adaptation is driven by time-varying surface pressure measurements at 2 locations on the square cylinder. The RCA-RANS k- ω model reduces the average surface-pressure error at these locations by 88.8%.

Genetically encoded calcium indicators for multi-color neural activity imaging and combination with optogenetics

Directory of Open Access Journals (Sweden)

Jasper eAkerboom

2013-03-01

Full Text Available Genetically encoded calcium indicators (GECIs are powerful tools for systems neuroscience. Here we describe red, single-wavelength GECIs, RCaMPs, engineered from circular permutation of the thermostable red fluorescent protein mRuby. High-resolution crystal structures of mRuby, the red sensor RCaMP, and the recently published red GECI R-GECO1 give insight into the chromophore environments of the Ca2+-bound state of the sensors and the engineered protein domain interfaces of the different indicators. We characterized the biophysical properties and performance of RCaMP sensors in vitro and in vivo in Caenorhabditis elegans, Drosophila larvae, and larval zebrafish. Further, we demonstrate 2-color calcium imaging both within the same cell (registering mitochondrial and somatic [Ca2+] and between two populations of cells: neurons and astrocytes. Finally, we perform integrated optogenetics experiments, wherein neural activation via channelrhodopsin-2 (ChR2 or a red-shifted variant, and activity imaging via RCaMP or GCaMP, are conducted simultaneously, with the ChR2/RCaMP pair providing independently addressable spectral channels. Using this paradigm, we measure calcium responses of naturalistic and ChR2-evoked muscle contractions in vivo in crawling C. elegans. We systematically compare the RCaMP sensors to R-GECO1, in terms of action potential-evoked fluorescence increases in neurons, photobleaching, and photoswitching. R-GECO1 displays higher Ca2+ affinity and larger dynamic range than RCaMP, but exhibits significant photoactivation with blue and green light, suggesting that integrated channelrhodopsin-based optogenetics using R-GECO1 may be subject to artifact. Finally, we create and test blue, cyan and yellow variants engineered from GCaMP by rational design. This engineered set of chromatic variants facilitates new experiments in functional imaging and optogenetics.

Effects of nicorandil on coronary collateral circulation depend on the donor arteries

International Nuclear Information System (INIS)

Umezawa, Shigeo; Ogawara, Shigeko; Okamoto, Yoshihiro; Igawa, Masayuki; Aonuma, Kazutaka; Inada, Mihoe; Korenaga, Masayoshi; Hiroe, Michiaki; Marumo, Fumiaki.

1996-01-01

The effects of nicorandil on coronary collateral circulation during exercise-induced ischemia were compared between the different donor arteries in 13 patients with effort angina, 7 with complete obstruction of the left anterior descending artery (LAD) with well-developed collateral vessels from the right coronary artery (RCA) (LAD group), and 6 with complete occlusion of the RCA (segment 2-3) with well-developed collateral vessels from the LAD (RCA group). Initial percentage thallium (%Tl) uptake (thallium-201 single photon emission computed tomography) and washout rate were measured in the anterior, septal and posterior regions during ergometer exercise. The submaximal treadmill exercise test was also performed using a cardiopulmonary monitoring system to measure Vo 2 at anaerobic threshold (AT). After the controls were obtained, nicorandil (15 mg/day) was administered for 4 weeks, during which ergometer exercise and treadmill exercise tests were carried out repeatedly. A significant improvement of initial %Tl uptake on exercise was observed in the LAD group with nicorandil therapy, but no improvement was shown in the RCA group. The AT significantly increased after nicorandil treatment in the LAD group (13.9±0.38 → 16.8±1.18 ml/min/kg), reflecting the improvement of cardiac function through the increased collateral flow. However, in the RCA group, it remained unchanged, suggesting no improvement of cardiac function. Nicorandil was effective to increase collateral flow from the RCA, but ineffective on that from the LAD. Nicorandil is an effective coronary dilator and is reported to affect both large and small coronary arteries. The effect on the collateral circulation is dependent on the donor artery supplying different areas. The vasodilator effect of nicorandil is mainly on the LAD, which is large enough to supply blood to a wider area of the heart, rather than the RCA. (author)

Evaluation of rainfall simulations over West Africa in dynamically downscaled CMIP5 global circulation models

Science.gov (United States)

Akinsanola, A. A.; Ajayi, V. O.; Adejare, A. T.; Adeyeri, O. E.; Gbode, I. E.; Ogunjobi, K. O.; Nikulin, G.; Abolude, A. T.

2018-04-01

This study presents evaluation of the ability of Rossby Centre Regional Climate Model (RCA4) driven by nine global circulation models (GCMs), to skilfully reproduce the key features of rainfall climatology over West Africa for the period of 1980-2005. The seasonal climatology and annual cycle of the RCA4 simulations were assessed over three homogenous subregions of West Africa (Guinea coast, Savannah, and Sahel) and evaluated using observed precipitation data from the Global Precipitation Climatology Project (GPCP). Furthermore, the model output was evaluated using a wide range of statistical measures. The interseasonal and interannual variability of the RCA4 were further assessed over the subregions and the whole of the West Africa domain. Results indicate that the RCA4 captures the spatial and interseasonal rainfall pattern adequately but exhibits a weak performance over the Guinea coast. Findings from the interannual rainfall variability indicate that the model performance is better over the larger West Africa domain than the subregions. The largest difference across the RCA4 simulated annual rainfall was found in the Sahel. Result from the Mann-Kendall test showed no significant trend for the 1980-2005 period in annual rainfall either in GPCP observation data or in the model simulations over West Africa. In many aspects, the RCA4 simulation driven by the HadGEM2-ES perform best over the region. The use of the multimodel ensemble mean has resulted to the improved representation of rainfall characteristics over the study domain.

The contribution of nuclear-related technical cooperation to national development

International Nuclear Information System (INIS)

Cook, D.

1988-01-01

The present situation of nuclear technical assistance and the IAEA's programs are reviewed. The perspectives of the developing and of the developed countries are discussed. Australia's aid administrators have been showing an increasing preference for administering its nuclear technical assistance through the Regional Cooperation Agreement for Asia and the Pacific (RCA), because of its direct benefits to the countries in the region, its flexibility, its emphasis on training, and its cooperative nature. The RCA also benefits from IAEA management and IAEA and United Nations Development Program funding. Two examples of Australia's successful RCA activities are the 1988 radiation protection training course held in Sydney and one of the many individual projects within the 1980-86 RCA hydrology program - the application of radioisotope tracer techniques to locating the seepage areas in the Pedu dam in Kedah State, Malaysia. Australia's experience has shown that project design, successful training of the right people, adequate infrastructure in both donor and recipient countries, and detailed post-project evaluation are the keys to successful project implementation. The RCA has achieved wide recognition as a successful tool in nuclear-related technology transfer

Steam-deformed Judkins-left guiding catheter with use of the GuideLiner catheter to deliver stents for anomalous right coronary artery

Directory of Open Access Journals (Sweden)

Toshiki Kuno

2015-10-01

Full Text Available Objective: Percutaneous coronary intervention for anomalous right coronary artery (RCA originating from the left coronary cusp is challenging because of our current inability to coaxially engage the guiding catheter. Methods: We report a case of an 88-year-old woman with non-ST segment elevation myocardial infarction, with an anomalous RCA origin. Using either the Judkins-Left catheter or Amplatz-Left catheter was difficult because of RCA ostium tortuosity. Thus, we used steam to deform the Judkins-Left catheter, but back-up support was insufficient to deliver the stent. Results: We used GuideLiner®, a novel pediatric catheter with rapid exchange/monorail systems, to enhance back-up support. Conclusions: We were able to successfully stent with both the deformed Judkins-Left guiding catheter and GuideLiner® for an anomalous RCA origin.

A rare anomaly: Double right coronary artery

Directory of Open Access Journals (Sweden)

Dursun Çayan Akkoyun

2013-01-01

Full Text Available Coronary artery anomalies are rare anomalies. Theseare usually asymptomatic and are discovered incidentally.Double right coronary artery (RCA is a rare coronaryartery anomaly. Although there is controversy aboutidentification and classification of double RCA, it is oftena benign condition, but it can be complicated by atherosclerosisand can lead to serious conditions such asmyocardial infarction (MI and may be accompanied byother anomalies. In our case, double RCA were detectedin coronary angiography for acute anterior MI, and in thenext session successful percutaneous coronary interventionwas performed.Key words: Coronary anomaly, coronary angiography,coronary stenosis

Recycled concrete aggregate in portland cement concrete.

Science.gov (United States)

2013-01-01

Aggregates can be produced by crushing hydraulic cement concrete and are known as recycled concrete : aggregates (RCA). This report provides results from a New Jersey Department of Transportation study to identify : barriers to the use of RCA in new ...

REPRODUCTION DE LA TRUITE (Salmo trutta L. DANS LETORRENT DE CHEVENNE, HAUTE-SAVOIE.UN FONCTIONNEMENT ORIGINAL ?

Directory of Open Access Journals (Sweden)

CHAMPIGNEULLE A.

2003-01-01

Full Text Available La reproduction d’une population de truite (Salmo trutta L. de forme essentiellement méditerranéenne est décrite dans le ruisseau du Chevenne, un torrent à forte pente (10 % entrecoupé d’obstacles et limité en substrat de frai, situé dans les Alpes savoyardes. Les reproducteurs (résidents du torrent ou migrants issus du cours principal diffèrent en taille et sexe-ratio. La majorité (58 % des femelles migrantes entrent dans l’affluent déjà ovulées. Il existe une fort gradient décroissant aval-amont dans la répartition des géniteurs et des frayères. Les 157 frayères décrites montrent une grande diversité de microhabitats (5 types principaux utilisés pour la reproduction, avec un pourcentage élevé (65 % de frayères construites dans des sites protégés ayant une faible vitesse de courant (< 20 cm/s. La reproduction débute en radier, l’habitat de frai classique, puis elle s’étend ensuite aux autres microhabitats avant que le frai en milieu radier ne soit achevé. Une évaluation de la disponibilité et de l’utilisation du substrat favorable au frai (taille de 1 à 3 cm dans les divers microhabitats a été réalisée a posteriori. Le microhabitat « côté de pool » (inhabituel pour le frai est autant utilisé que le milieu radier. Les lentilles de substrat favorable, abritées en bordure de berge ou dans les courants sont préférées alors que les lentilles de substrat non protégées dans les courants sont évitées. Une crue en fin de la période de frai a totalement détruit 36 % des frayères avec un taux de destruction totale très variable selon le type de microhabitat de frai. Les frayères creusées en côté de pool et en bordure de berge protégées du courant ont été moins détruites (15-17 % de destruction totale que dans les autres microhabitats (50 à 67 % de destruction totale. La diversité des sites de frai pourrait donc être une composante essentielle à la survie de la population de

South Asia | Page 192 | IDRC - International Development Research ...

International Development Research Centre (IDRC) Digital Library (Canada)

Although economic growth has reduced poverty in much of Asia, rural and ... These pressures strain the infrastructure and fray human relations, ultimately hampering development. ... Our regional office for Asia is located in New Delhi, India.

South Asia | Page 191 | IDRC - International Development Research ...

International Development Research Centre (IDRC) Digital Library (Canada)

Although economic growth has reduced poverty in much of Asia, rural and ... These pressures strain the infrastructure and fray human relations, ultimately hampering development. ... Our regional office for Asia is located in New Delhi, India.

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International Development Research Centre (IDRC) Digital Library (Canada)

Although economic growth has reduced poverty in much of Asia, rural and ... These pressures strain the infrastructure and fray human relations, ultimately hampering development. ... Our regional office for Asia is located in New Delhi, India.

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International Development Research Centre (IDRC) Digital Library (Canada)

Although economic growth has reduced poverty in much of Asia, rural and ... These pressures strain the infrastructure and fray human relations, ultimately hampering development. ... Our regional office for Asia is located in New Delhi, India.

Evaluation of genetic diversity of Portuguese Pinus sylvestris L.

Indian Academy of Sciences (India)

Home; Journals; Journal of Genetics; Volume 92; Online resources. Evaluation of genetic diversity of Portuguese Pinus sylvestris L. populations based on molecular data and inferences about the future use of this germplasm. J. Cipriano A. Carvalho C. Fernandes M. J. Gaspar J. Pires J. Bento L. Roxo J. Louzada J. Lima- ...

Evaluation of the environmental, material, and structural performance of recycled aggregate concrete

Science.gov (United States)

Michaud, Katherine Sarah

Concrete is the most commonly used building material in the construction industry, and contributes to 52% of construction and demolition waste in Canada. Recycled concrete aggregate (RCA) is one way to reduce this impact. To evaluate the performance of coarse and granular (fine and coarse) RCA in structural concrete applications, four studies were performed: an environmental assessment, a material testing program, a shear performance study, and a flexural performance study. To determine the environmental benefits of recycled aggregate concrete (RAC), three case studies were investigated using different populations and proximities to city centres. Environmental modelling suggested that RCA replacement could result in energy savings and greenhouse gas emission reductions, especially in remote areas. Tests were performed to determine if the volumetric replacement of up to 30% coarse RCA and 20% granular RCA is suitable for structural concrete applications in Canada. Fresh, hardened, and durability properties were evaluated. All five (5) of the RCA mixes showed equivalent material performance to the control mixes and met the requirements for a structural concrete mix. The five (5) RAC mixes were also used in structural testing. One-way reinforced concrete slab specimens were tested to failure to evaluate the shear and flexural performance of the RAC members. Peak capacities of and crack formation within each member were analyzed to evaluate the performance of RAC compared to conventional concrete. The shear capacity of specimens made from four (4) of the five (5) RAC mixtures was higher or equivalent to the control specimens. Specimens of the concrete mixture containing the highest content of recycled aggregate, 20% volumetric replacement of granular RCA, had shear capacities 14.1% lower, and exhibited cracking at lower loads than the control. The average flexural capacities of all RAC specimens were within 3.7% of the control specimens. Results from this research

An Analysis of Adverse Events in the Rehabilitation Department: Using the Veterans Affairs Root Cause Analysis System.

Science.gov (United States)

Hagley, Gregory W; Mills, Peter D; Shiner, Brian; Hemphill, Robin R

2018-04-01

Root cause analyses (RCA) are often completed in health care settings to determine causes of adverse events (AEs). RCAs result in action plans designed to mitigate future patient harm. National reviews of RCA reports have assessed the safety of numerous health care settings and suggested opportunities for improvement. However, few studies have assessed the safety of receiving care from physical therapists, occupational therapists, or speech and language pathology pathologists. The objective of this study was to determine the types of AEs, root causes, and action plans for risk mitigation that exist within the disciplines of rehabilitation medicine. This study is a retrospective, cross-sectional review. A national search of the Veterans Health Administration RCA database was conducted to identify reports describing AEs associated with physical therapy, occupational therapy, or speech and language pathology services between 2009 and May 2016. Twenty-five reports met the inclusion requirements. The reports were classified by the event type, root cause, action plans, and strength of action plans. Delays in care (32.0%) and falls (28.0%) were the most common type of AE. Three AEs resulted in death. RCA teams identified deficits regarding policy and procedures as the most common root cause. Eighty-eight percent of RCA reports included strong or intermediate action plans to mitigate risk. Strong action plans included standardizing emergency terminology and implementing a dedicated line to call for an emergency response. These data are self-reported and only AEs that are scored as a safety assessment code 3 in the system receive a full RCA, so there are likely AEs that were not captured in this study. In addition, the RCA reports are deidentified and so do not include all patient characteristics. As the Veterans Health Administration system services mostly men, the data might not generalize to non-Veterans Health Administration systems with a different patient mix. Care

Shadows at Europe's heart

Index Scriptorium Estoniae

2006-01-01

Ülevaade Kesk- ja Ida-Euroopa riikide sisepoliitilistest konfliktidest, ebakompetentsuse ning korruptsiooni ilmingutest valitsustes. Toomas Hendrik Ilves kui positiivne näide Brüsselist kodumaale naasnud poliitikust. Vt. ka lk. 13-14: Europe's fraying fringe

Comminution and sizing processes of concrete block waste as recycled aggregates.

Science.gov (United States)

Gomes, P C C; Ulsen, C; Pereira, F A; Quattrone, M; Angulo, S C

2015-11-01

Due to the environmental impact of construction and demolition waste (CDW), recycling is mandatory. It is also important that recycled concrete aggregates (RCA) are used in concrete to meet market demands. In the literature, the influence of RCAs on concrete has been investigated, but very limited studies have been conducted on how the origin of concrete waste and comminution processes influence RCA characteristics. This paper aims to investigate the influence of three different comminution and sizing processes (simple screening, crushing and grinding) on the composition, shape and porosity characteristics of RCA obtained from concrete block waste. Crushing and grinding implies a reduction of RCA porosity. However, due to the presence of coarse quartz rounded river pebbles in the original concrete block mixtures, the shape characteristics deteriorated. A large amount of powder (<0.15 mm) without detectable anhydrous cement was also generated. Copyright © 2015 Elsevier Ltd. All rights reserved.

The mechanical properties of brick containing recycled concrete aggregate and polyethylene terephthalate waste as sand replacement

Science.gov (United States)

Sheikh Khalid, Faisal; Bazilah Azmi, Nurul; Natasya Mazenan, Puteri; Shahidan, Shahiron; Ali, Noorwirdawati

2018-03-01

This research focuses on the performance of composite sand cement brick containing recycle concrete aggregate and waste polyethylene terephthalate. This study aims to determine the mechanical properties such as compressive strength and water absorption of composite brick containing recycled concrete aggregate (RCA) and polyethylene terephthalate (PET) waste. The bricks specimens were prepared by using 100% natural sand, they were then replaced by RCA at 25%, 50% and 75% with proportions of PET consists of 0.5%, 1.0% and 1.5% by weight of natural sand. Based on the results of compressive strength, only RCA 25% with 0.5% PET achieve lower strength than normal bricks while others showed a high strength. However, all design mix reaches strength more than 7N/mm2 as expected. Besides that, the most favorable mix design that achieves high compressive strength is 75% of RCA with 0.5% PET.

Anomalous Coronary Artery From the Opposite Sinus (ACAOS): Technical Challenges During Percutaneous Coronary Intervention.

Science.gov (United States)

Sinha, Santosh Kumar; Razi, Mahmodula; Mahrotra, Anupam; Aggarwal, Puneet; Singh, Anupam; Rekwal, Lokendra; Tripathi, Sunil; Abhishekh, Nishant Kumar; Krishna, Vinay

2018-04-01

Anomalies of the coronary arteries are reported in 1-2% of patients among diagnostic angiogram. Ectopic origin of right coronary artery (RCA) from opposite sinus is one of the most common and they are mainly benign, but at times may be malignant. We report a case of a 69-year-old male who underwent early invasive percutaneous coronary intervention for non-ST-segment elevation myocardial infarction (NSTEMI) where RCA arising from left sinus at the root of left main artery was culprit and various technical challenges were encountered while intervening in form of cannulation to tracking of hardwares. RCA was cannulated with floating wire technique using hockey stick guide catheter and revascularized by deployment of 3.5 × 38 mm Promus Premier Everolimus eluting stent (Boston Scientific, USA). To the best of our knowledge, this is the first ever report of ectopic RCA being revascularized by using hockey stick catheter.

Rare presentation of intralobar pulmonary sequestration associated with repeated episodes of ventricular tachycardia.

Science.gov (United States)

Rao, D Sheshagiri; Barik, Ramachandra

2016-07-26

Arterial supply of an intralobar pulmonary sequestration (IPS) from the coronary circulation is extremely rare. A significant coronary steal does not occur because of dual or triple sources of blood supply to sequestrated lung tissue. We present a 60-year-old woman who presented to us with repeated episodes of monomorphic ventricular tachycardia (VT) in last 3 mo. Radio frequency ablation was ineffective. On evaluation, she had right lower lobe IPS with dual arterial blood supply, i.e., right pulmonary artery and the systemic arterial supply from the right coronary artery (RCA). Stress myocardial perfusion scan revealed significant inducible ischemia in the RCA territory. Coronary angiogram revealed critical stenosis of proximal RCA just after the origin of the systemic artery supplying IPS. The critical stenosis in the RCA was stented. At 12 mo follow-up, she had no further episodes of VT or angina.

Linear reversible second-order cellular automata and their first-order matrix equivalents

Science.gov (United States)

Macfarlane, A. J.

2004-11-01

Linear or one-dimensional reversible second-order cellular automata, exemplified by three cases named as RCA1-3, are introduced. Displays of their evolution in discrete time steps, &{\\in}Z_2;) as for RCA1-3. MCA1-3 are tractable because it has been possible to generalize to them the heavy duty methods already well-developed for ordinary first-order cellular automata like those of Wolfram's Rules 90 and 150. While the automata MCA1-3 are thought to be of genuine interest in their own right, with untapped further mathematical potential, their treatment has been applied here to expediting derivation of a large body of general and explicit results for N(t) for RCA1-3. Amongst explicit results obtained are formulas also for each of RCA1-3 for the total weight of the configurations of the first &2^M; times, M =0, 1, 2,\\ldots.

Arctic climate change in an ensemble of regional CORDEX simulations

Directory of Open Access Journals (Sweden)

Torben Koenigk

2015-03-01

Full Text Available Fifth phase Climate Model Intercomparison Project historical and scenario simulations from four global climate models (GCMs using the Representative Concentration Pathways greenhouse gas concentration trajectories RCP4.5 and RCP8.5 are downscaled over the Arctic with the regional Rossby Centre Atmosphere model (RCA. The regional model simulations largely reflect the circulation bias patterns of the driving global models in the historical period, indicating the importance of lateral and lower boundary conditions. However, local differences occur as a reduced winter 2-m air temperature bias over the Arctic Ocean and increased cold biases over land areas in RCA. The projected changes are dominated by a strong warming in the Arctic, exceeding 15°K in autumn and winter over the Arctic Ocean in RCP8.5, strongly increased precipitation and reduced sea-level pressure. Near-surface temperature and precipitation are linearly related in the Arctic. The wintertime inversion strength is reduced, leading to a less stable stratification of the Arctic atmosphere. The diurnal temperature range is reduced in all seasons. The large-scale change patterns are dominated by the surface and lateral boundary conditions so future response is similar in RCA and the driving global models. However, the warming over the Arctic Ocean is smaller in RCA; the warming over land is larger in winter and spring but smaller in summer. The future response of winter cloud cover is opposite in RCA and the GCMs. Precipitation changes in RCA are much larger during summer than in the global models and more small-scale change patterns occur.

Data on optimum recycle aggregate content in production of new structural concrete.

Science.gov (United States)

Paul, Suvash Chandra

2017-12-01

This data presented herein are the research summary of "mechanical behavior and durability performance of concrete containing recycled concrete aggregate" (Paul, 2011) [1]. The results reported in this article relate to an important parameter of optimum content of recycle concrete aggregate (RCA) in production of new concrete for both structural and non-structural applications. For the purpose of the research various types of physical, mechanical and durability tests are performed for concrete made with different percentages of RCA. Therefore, this data set can be a great help of the readers to understand the mechanism of RCA in relates to the concrete properties.

Primer Extension Mutagenesis Powered by Selective Rolling Circle Amplification

Science.gov (United States)

Huovinen, Tuomas; Brockmann, Eeva-Christine; Akter, Sultana; Perez-Gamarra, Susan; Ylä-Pelto, Jani; Liu, Yuan; Lamminmäki, Urpo

2012-01-01

Primer extension mutagenesis is a popular tool to create libraries for in vitro evolution experiments. Here we describe a further improvement of the method described by T.A. Kunkel using uracil-containing single-stranded DNA as the template for the primer extension by additional uracil-DNA glycosylase treatment and rolling circle amplification (RCA) steps. It is shown that removal of uracil bases from the template leads to selective amplification of the nascently synthesized circular DNA strand carrying the desired mutations by phi29 DNA polymerase. Selective RCA (sRCA) of the DNA heteroduplex formed in Kunkel's mutagenesis increases the mutagenesis efficiency from 50% close to 100% and the number of transformants 300-fold without notable diversity bias. We also observed that both the mutated and the wild-type DNA were present in at least one third of the cells transformed directly with Kunkel's heteroduplex. In contrast, the cells transformed with sRCA product contained only mutated DNA. In sRCA, the complex cell-based selection for the mutant strand is replaced with the more controllable enzyme-based selection and less DNA is needed for library creation. Construction of a gene library of ten billion members is demonstrated with the described method with 240 nanograms of DNA as starting material. PMID:22355397

Mechanical properties of recycled concrete with demolished waste concrete aggregate and clay brick aggregate

Science.gov (United States)

Zheng, Chaocan; Lou, Cong; Du, Geng; Li, Xiaozhen; Liu, Zhiwu; Li, Liqin

2018-06-01

This paper presents an experimental investigation on the effect of the replacement of natural coarse aggregate (NCA) with either recycled concrete aggregate (RCA) or recycled clay brick aggregate (RBA) on the compressive strengths of the hardened concrete. Two grades (C25 and C50) of concrete were investigated, which were achieved by using different water-to-cement ratios. In each grade concrete five different replacement rates, 0%, 25%, 50%, 75% and 100% were considered. In order to improve the performance of the recycled aggregates in the concrete mixes, the RCA and RBA were carefully sieved by using the optimal degradation. In this way the largest reduction in the 28-day compressive strength was found to be only 7.2% and 9.6% for C25 and C50 recycled concrete when the NCA was replaced 100% by RCA, and 11% and 13% for C25 and C50 recycled concrete when the NCA was replaced 100% by RBA. In general, the concrete with RCA has better performance than the concrete with RBA. The comparison of the present experimental results with those reported in literature for hardened concrete with either RCA or RBA demonstrates the effectiveness in improving the compressive strength by using the optimal gradation of recycled aggregates.

Root Cause Analysis: Learning from Adverse Safety Events.

Science.gov (United States)

Brook, Olga R; Kruskal, Jonathan B; Eisenberg, Ronald L; Larson, David B

2015-10-01

Serious adverse events continue to occur in clinical practice, despite our best preventive efforts. It is essential that radiologists, both as individuals and as a part of organizations, learn from such events and make appropriate changes to decrease the likelihood that such events will recur. Root cause analysis (RCA) is a process to (a) identify factors that underlie variation in performance or that predispose an event toward undesired outcomes and (b) allow for development of effective strategies to decrease the likelihood of similar adverse events occurring in the future. An RCA process should be performed within the environment of a culture of safety, focusing on underlying system contributors and, in a confidential manner, taking into account the emotional effects on the staff involved. The Joint Commission now requires that a credible RCA be performed within 45 days for all sentinel or major adverse events, emphasizing the need for all radiologists to understand the processes with which an effective RCA can be performed. Several RCA-related tools that have been found to be useful in the radiology setting include the "five whys" approach to determine causation; cause-and-effect, or Ishikawa, diagrams; causal tree mapping; affinity diagrams; and Pareto charts. © RSNA, 2015.

Evaluating the Carbonation Resistance of Self Compacting Concrete made with Recycled Concrete Aggregates

Directory of Open Access Journals (Sweden)

S P Singh

2016-07-01

Full Text Available The paper presents the results of an investigation conducted to examine carbonation resistance of Self Compacting Concrete (SCC made with coarse Recycled Concrete Aggregates (RCA. In total, five SCC mixes were prepared by systematically replacing coarse Natural Aggregates (NA by RCA at 0, 25, 50, 75 and 100%. In order to measure the carbonation resistance of SCC made with RCA, accelerated carbonation tests were performed for 4 and 12 weeks of exposure to carbon dioxide. The carbonation resistance has been evaluated after curing periods of 28 and 90 days. In addition to this, the compressive strength of all the mixes was also obtained after 7, 28 and 90 days of curing and ultra-sonic pulse velocity tests (UPV were also conducted. The results indicate that with the increase in the content of RCA as replacement of NA, decrease in the carbonation resistance, compressive strength and UPV was observed for all SCC mixes. It has been observed that the SCC mixes containing low percentages of RCA (i.e. 25% as replacement of NA do not impart detrimental behaviour in the overall performance but higher replacement levels (>50% have been found to deteriorate the performance in terms of carbonation resistance, compressive strength and UPV.

Industrial technology transfer in Asia and the Pacific

International Nuclear Information System (INIS)

Fowler, E.E.

1982-01-01

For ten years the Regional Co-operative Agreement for research, development and training related to nuclear science and technology (RCA) has brought together work of the IAEA and Member States in Asia and the Pacific. Current RCA projects concern health care, food and agriculture, hydrology, and industry - areas of great importance to participating Member States. Each of the nine projects emphasizes the use of well-developed nuclear technologies to improve the standard of living in the region. Applied research and development in areas of common interest to RCA Member States are promoted through these co-operative projects. Successful results are shared among participants. The industrial project, funded by the UNDP and executed by the IAEA, aims to expand and accelerate the uses of isotopes and radiation technology in five fields of industrial application. The industrial project is currently the largest project under the RCA: almost all parties to the agreement participate. Planned expenditures for the seven-year project total about US $12 500 000 (including UNDP funds and Government contributions). Like other projects under the RCA, the industrial project will serve the pressing economic and social needs of the Asia and Pacific region. It can serve as a model to be followed by other regions of the world

Performance of composite sand cement brick containing recycle concrete aggregate and waste polyethylene terephthalate with different mix design ratio

Science.gov (United States)

Azmi, N. B.; Khalid, F. S.; Irwan, J. M.; Mazenan, P. N.; Zahir, Z.; Shahidan, S.

2018-04-01

This study is focuses to the performance of composite sand cement brick containing recycle concrete aggregate and waste polyethylene terephthalate. The objective is to determine the mechanical properties such as compressive strength and water absorption of composite brick containing recycled concrete aggregate and polyethylene terephthalate waste and to determine the optimum mix ratio of bricks containing recycled concrete aggregate and polyethylene terephthalate waste. The bricks specimens were prepared by using 100% natural sand, they were then replaced by RCA at 25%, 50% and 75% with proportions of PET consists of 1.0%, 1.5%, 2.0% and 2.5% by weight of natural sand. Based on the results of compressive strength, it indicates that the replacement of RCA shows an increasing strength as the strength starts to increase from 25% to 50% for both mix design ratio. The strength for RCA 75% volume of replacement started to decrease as the volume of PET increase. However, the result of water absorption with 50% RCA and 1.0% PET show less permeable compared to control brick at both mix design ratio. Thus, one would expect the density of brick decrease and the water absorption to increase as the RCA and PET content is increased.

Biota acuática en la Amazonía Peruana: diversidad y usos como indicadores ambientales en el Bajo Urubamba (Cusco - Ucayali

Directory of Open Access Journals (Sweden)

Hernán Ortega

2011-05-01

Full Text Available En el presente trabajo se aplican índices biológicos de calidad ambiental y conservación, basados en el monitoreo biológico realizado entre año 2003 y 2009, en cinco localidades del río Bajo Urubamba. Fueron estudiadas las comunidades del plancton, bentos y peces. La diversidad del plancton comprendió 170 especies, basadas principalmente en Chlorophyta y Bacillariophyta. El bentos incluyó 112 especies, principalmente larvas y adultos de Arthropoda (Insecta. La diversidad de peces, incluye 176 especies, representadas por 26 familias y seis órdenes. El Índice Ephemeroptera + Plecoptera + Trichoptera (%EPT, califico el área de estudio entre normal a muy buena calidad. El índice de Integridad Biológica (IBI que determina el estado de conservación de los ambientes acuáticos, dio los mayores valores en Miaría y Sepahua. La elevada diversidad de las comunidades estudiados estaría relacionada a la heterogeneidad de hábitats y mayores recursos observados en la parte baja del área de estudio.

RCA annual report 1996. Draft

International Nuclear Information System (INIS)

1997-02-01

In accordance with Article VII.4 of the Regional Co-operative Agreement for Research, Development and Training Related to Nuclear Science and Technology 1987 and extended in 1992, a draft report of activities for the calendar year 1996 is submitted

Design of cryptographically secure AES like S-Box using second-order reversible cellular automata for wireless body area network applications

Science.gov (United States)

Rafi Ahamed, Shaik

2016-01-01

In biomedical, data security is the most expensive resource for wireless body area network applications. Cryptographic algorithms are used in order to protect the information against unauthorised access. Advanced encryption standard (AES) cryptographic algorithm plays a vital role in telemedicine applications. The authors propose a novel approach for design of substitution bytes (S-Box) using second-order reversible one-dimensional cellular automata (RCA2) as a replacement to the classical look-up-table (LUT) based S-Box used in AES algorithm. The performance of proposed RCA2 based S-Box and conventional LUT based S-Box is evaluated in terms of security using the cryptographic properties such as the nonlinearity, correlation immunity bias, strict avalanche criteria and entropy. Moreover, it is also shown that RCA2 based S-Boxes are dynamic in nature, invertible and provide high level of security. Further, it is also found that the RCA2 based S-Box have comparatively better performance than that of conventional LUT based S-Box. PMID:27733924

Fibromuscular Dysplasia Leading to Spontaneous Coronary Artery Dissection with Sudden Cardiac Arrest

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Ata Bajwa

2015-01-01

Full Text Available A 30-year-old previously healthy female, who was six-week postpartum, experienced sudden collapse and tonic-clonic seizure. Emergency medicine services arrived at the scene and the patient was found to be in ventricular fibrillation. Advanced cardiovascular life support (ACLS was initiated with return of spontaneous circulation. Afterwards, her initial EKG showed atrial fibrillation with rapid ventricular rate, ST elevation in leads II, III, and aVF, and ST depression in V2–V4. She was transferred to a tertiary care hospital where emergent angiogram was performed revealing obstruction of blood flow in the proximal and mid right coronary artery (RCA. A hazy and irregularly contoured appearance of the RCA was consistent with diagnosis of fibromuscular dysplasia. Subsequently, intravascular ultrasonogram (IVUS was performed which confirmed the diagnosis of RCA dissection. Successful revascularization of the RCA was performed using two bare mental stents. After a complicated course in hospital, she was discharged in stable condition and did very well overall.

Expression of Ricinus communis receptors on epithelial cells in oral carcinomas and oral wounds.

Science.gov (United States)

Dabelsteen, E; Mackenzie, I C

1978-12-01

The histological distribution of receptors for Ricinus communis Fraction 1 (RCA1) in oral carcinomas and in oral epithelial cells during wound healing has been studied by use of fluorescein-tagged RCA1. Biopsies from 15 human oral carcinomas and adjacent normal mucosa showed RCA1 receptors at the cell membranes in the basal and spinous layer of the normal epithelium, whereas receptors could not be demonstrated in invading islands of the tumors. In healing oral wounds from eight humans and three monkeys, RCA1 receptors were demonstrated both in normal epithelium adjacent to the wounds and in the epithelial outgrowth from the wound margin. Titrations, however, showed that the epithelial outgrowth reacted more weakly than did the normal adjacent epithelium. These results support previous in vitro studies showing changes in carbohydrate composition of moving normal cells and of malignant cells, a finding that may be of interest in relation to formation of metastases.

Design of cryptographically secure AES like S-Box using second-order reversible cellular automata for wireless body area network applications.

Science.gov (United States)

Gangadari, Bhoopal Rao; Rafi Ahamed, Shaik

2016-09-01

In biomedical, data security is the most expensive resource for wireless body area network applications. Cryptographic algorithms are used in order to protect the information against unauthorised access. Advanced encryption standard (AES) cryptographic algorithm plays a vital role in telemedicine applications. The authors propose a novel approach for design of substitution bytes (S-Box) using second-order reversible one-dimensional cellular automata (RCA 2 ) as a replacement to the classical look-up-table (LUT) based S-Box used in AES algorithm. The performance of proposed RCA 2 based S-Box and conventional LUT based S-Box is evaluated in terms of security using the cryptographic properties such as the nonlinearity, correlation immunity bias, strict avalanche criteria and entropy. Moreover, it is also shown that RCA 2 based S-Boxes are dynamic in nature, invertible and provide high level of security. Further, it is also found that the RCA 2 based S-Box have comparatively better performance than that of conventional LUT based S-Box.

The competitiveness of wood processing industry in the Republic of Serbia during the period 1995-2015

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Milićević Srđan

2017-01-01

Full Text Available The paper considers the competitiveness of wood processing industry in the Republic of Serbia in the period 1995-2015 by using six partial indicators of competitiveness: Revealed comparative advantage (RCA, Competitiveness growth index (RCA1, Index of net business performance (RCA2, Index of contribution to the trade balance (CTB, Grubel-Lloyd index (GLI and Michaely index (MI. The research reveals that the values of RCA were positive in all years, which points to comparative advantage of wood processing industry on the domestic market. Since RCA1 has significantly higher value than one, it means that it is highly competitive on international market as well. Positive values of RCA2 in the period 1995-2015 speak of the contribution of this branch to international economic balance. The indicator RCA2 is connected with the CTB index, which points to the contribution of the sector in formation of active national trade balance and economic growth. The average value of CTB index of wood processing industry in Serbia and positive annual values of CTB of wood processing industry show that the contribution in the total trade balance of the sector is positive. The course of GLI values points to the loss of capabilities of the sector to create the surplus of national trade balance. Finally, positive annual values of MI confirmed the competitiveness of domestic wood processing industry, but at the same time its low specialisation. Taken as a whole, the weakness of competitiveness of wood processing industry in Serbia can be seen in the fact that its competitive advantage is visible in its favourable price, not in manufacturing complex products with high value added. The aim of the paper is to investigate whether Serbian wood processing industry has comparative precedence on domestic and international markets and whether the structure of exchange is positive, i.e. whether appropriate specialisation of production and export exists or the focus should shift

Far East Asia | Page 87 | IDRC - International Development ...

International Development Research Centre (IDRC) Digital Library (Canada)

Although economic progress has reduced poverty, the region still suffers from important challenges such as inequities, violence targeting minorities, environmental depletion, growing informal employment, and food insecurity. These pressures strain the infrastructure and fray human relations, ultimately hampering ...

Linear reversible second-order cellular automata and their first-order matrix equivalents

International Nuclear Information System (INIS)

Macfarlane, A J

2004-01-01

Linear or one-dimensional reversible second-order cellular automata, exemplified by three cases named as RCA1-3, are introduced. Displays of their evolution in discrete time steps, t=0, 1, 2, ..., from their simplest initial states and on the basis of updating rules in modulo 2 arithmetic, are presented. In these, shaded and unshaded squares denote cells whose cell variables are equal to one and zero respectively. This paper is devoted to finding general formulas for, and explicit numerical evaluations of, the weights N(t) of the states or configurations of RCA1-3, i.e. the total number of shaded cells in tth line of their displays. This is achieved by means of the replacement of RCA1-3 by the equivalent linear first-order matrix automata MCA1-3, for which the cell variables are 2x2 matrices, instead of just numbers (element of Z 2 ) as for RCA1-3. MCA1-3 are tractable because it has been possible to generalize to them the heavy duty methods already well-developed for ordinary first-order cellular automata like those of Wolfram's Rules 90 and 150. While the automata MCA1-3 are thought to be of genuine interest in their own right, with untapped further mathematical potential, their treatment has been applied here to expediting derivation of a large body of general and explicit results for N(t) for RCA1-3. Amongst explicit results obtained are formulas also for each of RCA1-3 for the total weight of the configurations of the first 2 M times, M=0, 1, 2, ..

Real-time monitoring of mycobacterium genomic DNA with target-primed rolling circle amplification by a Au nanoparticle-embedded SPR biosensor.

Science.gov (United States)

Xiang, Yang; Zhu, Xiaoyan; Huang, Qing; Zheng, Junsong; Fu, Weiling

2015-04-15

In this study, we developed a surface plasmon resonance (SPR) DNA biosensor array based on target-primed rolling circle amplification (RCA) for isothermal and rapid detection of two pathogenic mycobacteria, Mycobacterium tuberculosis complex (MTBC) and Mycobacterium avium complex (MAC).The species-specific padlock probe (PLP) was designed to target the sequence in 16S-23S rRNA gene internal transcribed spacer (ITS). After ligation, the circularized PLP could be primed by the target sequence to initial RCA. The RCA performed simultaneously with the cleavage reaction to produce small fragments of single strand DNA which immediately hybridized with the probe immobilized on the sensor chip without denaturation. This process caused SPR angle changes on the chip surface, which made the detection for analysis from the solution achievable, and dynamic real-time RCA monitoring of mycobacterium possible. Besides, Au nanoparticles (AuNPs) were directly assembled onto the surface of the sensor chip via hexanedithiol (HDT) for the enhancement of sensitivity as a label-free detection system. Experimental results show that the signal enhancement by the target-primed RCA together with AuNPs-embedded surface caused at least10-fold increased sensitivity as compared with conventional RCA on bare SPR chip method. Within 40min amplification duration as low as 20amol of synthetic targets and 10(4)CFUmL(-1) of genomic DNA from clinical samples can be detected. The proposed method not only provides a simple design idea for liquid-phase amplification monitoring, but also apply it in clinical pathogen detection, which holds great promise in ultrasensitive bioassay in the future. Copyright © 2014. Published by Elsevier B.V.

Benefits of aggregates surface modification in concrete production

Science.gov (United States)

Junak, J.; Sicakova, A.

2017-10-01

In our study, recycled concrete aggregates (RCA), which surfaces had been modified by geopolymer material based on coal fly ash, were used to produce the concrete samples. In these samples, fraction 4/8 mm was replaced by recycled concrete aggregate with a range of 100%. To modify the surface of RCA was “Solo” and “Triple stage” modification used. On these samples real density, total water absorption and compressive strength were examined after 28, 90, 180 and 365 days of hardening. The highest compressive strength 56.8 MPa, after 365 days hardening, reached sample which had improved RCA surface by “Triple stage mixing”.

HV Switch Tube Development Program status report: April 28, 1978

International Nuclear Information System (INIS)

Winje, R.A.

1978-01-01

The HV Switch Tube Development Program encompassed development contracts to both Eimac (Division of Varian) and RCA. Both companies were required to develop a design for the tube and to build and test two tubes. The development program began in April, 1976. Currently, both companies have built tubes; Eimac has built one and RCA has built two. As initially built, both tubes exhibited unstable operation; however, RCA has implemented design changes which stabilized the tube operation. Eimac has a design modification which they believe will produce stable operation when the change is implemented. Both tubes have been tested to a limited degree and no other abnormal characteristics have been observed

Implementing systems thinking for infection prevention: The cessation of repeated scabies outbreaks in a respiratory care ward.

Science.gov (United States)

Chuang, Sheuwen; Howley, Peter P; Lin, Shih-Hua

2015-05-01

Root cause analysis (RCA) is often adopted to complement epidemiologic investigation for outbreaks and infection-related adverse events in hospitals; however, RCA has been argued to have limited effectiveness in preventing such events. We describe how an innovative systems analysis approach halted repeated scabies outbreaks, and highlight the importance of systems thinking for outbreaks analysis and sustaining effective infection prevention and control. Following RCA for a third successive outbreak of scabies over a 17-month period in a 60-bed respiratory care ward of a Taiwan hospital, a systems-oriented event analysis (SOEA) model was used to reanalyze the outbreak. Both approaches and the recommendations were compared. No nosocomial scabies have been reported for more than 1975 days since implementation of the SOEA. Previous intervals between seeming eradication and repeat outbreaks following RCA were 270 days and 180 days. Achieving a sustainable positive resolution relied on applying systems thinking and the holistic analysis of the system, not merely looking for root causes of events. To improve the effectiveness of outbreaks analysis and infection control, an emphasis on systems thinking is critical, along with a practical approach to ensure its effective implementation. The SOEA model provides the necessary framework and is a viable complementary approach, or alternative, to RCA. Copyright © 2015 Association for Professionals in Infection Control and Epidemiology, Inc. Published by Elsevier Inc. All rights reserved.

SURVIE EMBRYONNAIRE DU SAUMON ATLANTIQUE (SALMO SALAR L. DANS UN COURS D’EAU DU SUD DE SON AIRE DE RÉPARTITION, LA NIVELLE

Directory of Open Access Journals (Sweden)

DUMAS J.

2007-01-01

Full Text Available L’évaluation de la survie du saumon Atlantique entre la ponte et l’émergence des alevins hors des graviers est réalisée dans le bassin de la Nivelle dans les domaines accessible (trois tronçons et non accessible (trois tronçons aux géniteurs. Pour ce faire, des capsules d’incubation de 12 cm3, contenant des œufs fraîchement fécondés, sont insérées dans des frayères artificielles et naturelles. Le débit et la température de l’eau de surface, l’oxygène dissous des eaux de surface et interstitielle et les caractéristiques granulométriques du substrat des frayères sont contrôlés pendant toute la durée de l’expérience. La survie, de 28,6 % en moyenne dans l’ensemble des sites, est plus élevée dans les tronçons de l’amont (52,7 % dans la Très Haute Nivelle et son affluent, le Lapitxuri que dans les autres sites, dont ceux actuellement colonisés par l’espèce (21,5 %. Il n’est pas observé de différence de survie entre les frayères artificielles et naturelles. Les mortalités interviennent essentiellement lors des épisodes de crues avant l’éclosion. Une corrélation positive forte existe entre la saturation en oxygène de l’eau interstitielle et la survie. Pour une saturation minimum en oxygène au-dessous de 62 %, la survie reste inférieure à 27 %. En revanche, la composition granulométrique du substrat ne semble pas agir directement sur la survie. Ce facteur n’étant pas corrélé avec l’oxygène dissous, ceci suggère que dans ce cours d’eau, le flux circulant dans les frayères ne provient pas uniquement de l’eau de surface, mais aussi de la nappe alluviale pauvre en oxygène dissous.

Systemic Vulnerabilities to Suicide among Veterans from the Iraq and Afghanistan Conflicts: Review of Case Reports from a National Veterans Affairs Database

Science.gov (United States)

Mills, Peter D.; Huber, Samuel J.; Watts, Bradley Vince; Bagian, James P.

2011-01-01

While suicide among recently returned veterans is of great concern, it is a relatively rare occurrence within individual hospitals and clinics. Root cause analysis (RCA) generates a detailed case report that can be used to identify system-based vulnerabilities following an adverse event. Review of a national database of RCA reports may identify…

Burns

Science.gov (United States)

... putting a child in the bathtub. Cover unused electric outlets with safety caps, and replace damaged, frayed or brittle electrical cords. Keep fire extinguishers on every floor of your house, especially in the kitchen, and know how to use them. Do not ...

Effects of a 3D segmental prosthetic system for tricuspid valve annulus remodelling on the right coronary artery: a human cadaveric coronary angiography study.

Science.gov (United States)

Riki-Marishani, Mohsen; Gholoobi, Arash; Sazegar, Ghasem; Aazami, Mathias H; Hedjazi, Aria; Sajjadian, Maryam; Ebrahimi, Mahmoud; Aghaii-Zade Torabi, Ahmad

2017-09-01

A prosthetic system to repair secondary tricuspid valve regurgitation was developed. The conceptual engineering of the current device is based on 3D segmental remodelling of the tricuspid valve annulus in lieu of reductive annuloplasty. This study was designed to investigate the operational safety of the current prosthetic system with regard to the anatomical integrity of the right coronary artery (RCA) in fresh cadaveric human hearts. During the study period, from January to April 2016, the current prosthetic system was implanted on the tricuspid valve annulus in fresh cadaveric human hearts that met the study's inclusion criteria. The prepared specimens were investigated via selective coronary angiography of the RCA in the catheterization laboratory. The RCA angiographic anatomies were categorized as normal, distorted, kinked or occluded. Sixteen specimens underwent implantation of the current prosthetic system. The mean age of the cadaveric human hearts was 43.24 ± 15.79 years, with vehicle accident being the primary cause of death (59%). A dominant RCA was noticed in 62.5% of the specimens. None of the specimens displayed any injury, distortion, kinking or occlusion in the RCA due to the implantation of the prostheses. In light of the results of the present study, undertaken on fresh cadaveric human heart specimens, the current segmental prosthetic system for 3D remodelling of the tricuspid valve annulus seems to be safe vis-à-vis the anatomical integrity of the RCA. Further in vivo studies are needed to investigate the functional features of the current prosthetic system with a view to addressing the complex pathophysiology of secondary tricuspid valve regurgitation. © The Author 2017. Published by Oxford University Press on behalf of the European Association for Cardio-Thoracic Surgery. All rights reserved.

Quality assessment of atmospheric surface fields over the Baltic Sea from an ensemble of regional climate model simulations with respect to ocean dynamics

Directory of Open Access Journals (Sweden)

H. E. Markus Meier

2011-05-01

Full Text Available Climate model results for the Baltic Sea region from an ensemble of eight simulations using the Rossby Centre Atmosphere model version 3 (RCA3 driven with lateral boundary data from global climate models (GCMs are compared with results from a downscaled ERA40 simulation and gridded observations from 1980-2006. The results showed that data from RCA3 scenario simulations should not be used as forcing for Baltic Sea models in climate change impact studies because biases of the control climate significantly affect the simulated changes of future projections. For instance, biases of the sea ice cover in RCA3 in the present climate affect the sensitivity of the model's response to changing climate due to the ice-albedo feedback. From the large ensemble of available RCA3 scenario simulations two GCMs with good performance in downscaling experiments during the control period 1980-2006 were selected. In this study, only the quality of atmospheric surface fields over the Baltic Sea was chosen as a selection criterion. For the greenhouse gas emission scenario A1B two transient simulations for 1961-2100 driven by these two GCMs were performed using the regional, fully coupled atmosphere-ice-ocean model RCAO. It was shown that RCAO has the potential to improve the results in downscaling experiments driven by GCMs considerably, because sea surface temperatures and sea ice concentrations are calculated more realistically with RCAO than when RCA3 has been forced with surface boundary data from GCMs. For instance, the seasonal 2 m air temperature cycle is closer to observations in RCAO than in RCA3 downscaling simulations. However, the parameterizations of air-sea fluxes in RCAO need to be improved.

Right ventricular function after acute myocardial infarction: dependence upon infarct related coronary artery

International Nuclear Information System (INIS)

Cho, Ihn Ho; Chun, Kyung A; Won, Kyu Chang; Lee, Hyung Woo; Hong, Geu Ru; Park, Jong Seon; Shin, Dong Gu; Kim, Young Jo; Shim, Bong Sub

2004-01-01

We studied to know the relation between right ventricular function and infarct-related artery after acute myocardial infarction. The right and left ventricular function after a first myocardial infarction was assessed ECG-gated blood pool single photon emission computed tomography (GBPS) algorithms (Cedars-Sinai Medical Center, Los Angels, Calif) (12 after LAD related infarction (group 1) and 15 after RCA related infarction (group 2)). The left ventricular ejection fraction, end-diastolic volume and end-systolic volume did not differ significantly between two groups( group 1 vs 2 :LVEF 50.8% vs 55.1%. LVEDV=73.2 vs 79.7 ml, LVESV=38 vs 44 ml : P>0.05), but right ventricular ejection fraction, end-diastolic volume and end-systolic volume were significantly different after anterior myocardial infarction between two groups( group 1 vs 2 : RVEF=57.3% vs 46.3%. RVEDV=56.4 vs 95.1 ml, RVESV=25.6 vs 54.6ml : P<0.05). There was evidence of right ventricular dilatation in the group with RCA related infarction. Six with inferior infarction had abnormal right ventricular ejection fractions (< 40%). The relation between right and left ventricular ejection fractions was markedly different in the two groups. In the group with RCA related infarction there was a significant linear relation between right and left ventricular ejection fraction(R=0.5). Whereas in the group with LAD related infarction there was not (R=-0.3). Thus right ventricular dysfunction commonly occurs after RCA related infarction. Right ventricular impairment is related after RCA related infarction, but are independent after LAD related infarction. Finally, the different effects of LAD and RCA related infarction on right ventricular function may be explained by site of the myocardial wall involvement after infarction

International Atomic Energy Agency: activities in Malaysia

Energy Technology Data Exchange (ETDEWEB)

Hayati, Ainul [Nuclear Energy Unit, Bangi, Selangor (Malaysia)

1994-12-31

The two main IAEA activities participated by Malaysia - technical cooperation programme (TC) and regional cooperative agreement programme (RCA/IAEA AND IAEA/RCA/UNDP). This article highlighted some of the IAEA technical cooperation activities in Malaysia (i.e. Medicine, Agriculture, Industry, Strategic, Social Science), assistance, funding and contribution made by Malaysia to the IAEA since 1989.

International Atomic Energy Agency: activities in Malaysia

International Nuclear Information System (INIS)

Ainul Hayati

1994-01-01

The two main IAEA activities participated by Malaysia - technical cooperation programme (TC) and regional cooperative agreement programme (RCA/IAEA AND IAEA/RCA/UNDP). This article highlighted some of the IAEA technical cooperation activities in Malaysia (i.e. Medicine, Agriculture, Industry, Strategic, Social Science), assistance, funding and contribution made by Malaysia to the IAEA since 1989

Revealed Comparative Advantage and the Alternatives as Measures of International Specialization

DEFF Research Database (Denmark)

Laursen, Keld

2015-01-01

This paper provides an analysis of Balassa's 'revealed comparative advantage' (RCA). It shows that when using RCA, it should be adjusted such that it becomes symmetric around its neutral value. The proposed adjusted index is called 'revealed symmetric comparative advantage' (RSCA). The theoretica...... Balance, Chi Square, and Bowen's Net Trade Index. The result of the analysis is that RSCA-on balance-is the best measure of comparative advantage....... discussion focuses on the properties of RSCA and empirical evidence, based on the Jarque-Bera test for normality of the regression error terms, using both the RCA and RSCA indices. We compare RSCA to other measures of international trade specialization including the Michaely index, the Contribution to Trade...

Nuclear targets, recoil ion catchers and reaction chambers

NARCIS (Netherlands)

Dionisio, JS; Vieu, C; Schuck, C; Collatz, R; Meunier, R; Ledu, D; Folger, H; Lafoux, A; Lagrange, JM; Pautrat, M; Waast, B; Phillips, WR; Blunt, D; Durell, JL; Varley, BJ; Dagnall, PG; Dorning, SJ; JONES, MA; Smith, AG; Bacelar, JCS; Rzaca-Urban, T; Amzal, N; Meliani, Z; Vanhorenbeeck, J; Passoja, A; Urban, W

1998-01-01

The main features of nuclear targets, recoil ion catchers and reaction chambers used in nuclear spectroscopic investigations involving in-beam multi-e-gamma spectrometers are discussed. The relative importance of the F-ray background due to the accelerated ion-target and the recoil-ion-target

Anomalous origin of the right coronary artery with an interarterial course and intramural part

Directory of Open Access Journals (Sweden)

Simon Fuglsang

2015-01-01

Conclusion: In this report, we present some unique images of the RCAs course, which contribute to the understanding of this disease’s symptomatology. The patient successfully underwent surgery with Right Internal Mammary Artery to RCA (RIMA–RCA2 RIMA–RCA = right Internal mammary artery to right coronary artery. bypass with complete remission of all symptoms.

Doing HOF work in NPP - an internal specialist point of view

International Nuclear Information System (INIS)

Koistinen, Petri

2011-01-01

Organisational learning has been identified as one success factor both in general business literature and also in nuclear industry. One part of organisational learning is routines that support organisational learning. In nuclear industry learning from events is an important process of organisational learning. The other building blocks of learning organisation are climate that supports learning and leadership that encourages learning. These have also been identified in nuclear industry as being important issues. Learning from events relies on the validity of the investigation process. Investigation process and report has simply three parts: what happened (facts), why it happened (analysis) and how to prevent reoccurrence (corrective actions, CA). In RCA analysis part is highlighted, however it cannot be done correctly unless the facts have not been collected well. In a good learning process there must also be a follow up and feedback system for CA's. The following are the key points from this presentation: - Koistinen has been an internal HOF specialist since 2004; still the only HOF specialist at TVO. - Main duties are event investigations (including RCA), operating experience, safety culture improvement, human performance and organisational development issues. - Human error is typically the end point of an investigation - Koistinen's job is to find out what has led a good professional to make an error (organisational factors). - A blame-free or just culture is required to identify the organisational issues in an event. - RCA is used for the most serious events - about 5 RCA like investigations are conducted at the two TVO units per year. - Finland does not have RCA training available and so staff must go elsewhere. Those working in event investigations are usually new in the nuclear business and therefore lack experience. - The author presents a number of guidelines from STUK, the Finnish regulatory body. There are requirements for competence of investigators

Clostridium difficile multidisciplinary team root cause analysis: impact on clinical care and circumvention of financial penalties posed by clinical commissioning groups, but at what cost?

Science.gov (United States)

Saeed, Kordo; Petridou, Christina; Gray, Hazel; Dryden, Matthew; Davis-Blues, Karen; Lucero, Sheryl; Parker, Natalie; Keyser, Taryn; Matthews, Tanya; Cortes, Nick; Kidd, Stephen; Thomas, Claire; Peacock, Heather; Hornzee, Joanna; Wake, Bruce

2018-03-01

In Hampshire Hospitals NHS Foundation Trust, in addition to an on-the-spot investigation into hospital-onset Clostridium difficile infection (CDI) by the infection prevention team, a multidisciplinary team root cause analysis (MDT-RCA) forum has been developed. The MDT-RCA aims to deliver a more thorough investigation into individual cases and the recommendation of cases to the clinical commissioning groups (CCG) appeals panel against potential financial penalties (£10,000 per breached case). We mainly aimed to investigate the financial impact of MDT-RCAs to the Trust. Over two years, 84 cases of hospital-onset CDI cases were reviewed by the MDT-RCA forum. Among this cohort, no additional learning outcomes were identified by the MDT-RCAs over those that were found by on-the-spot investigations. In total, 543 staff members attended the MDT-RCAs at a potential cost to the Trust of £23,795.74-£51,670.10. The Trust appealed against financial penalties for 27 cases and 14 were successful, i.e. £140,000 would have been avoided had targets been breached by 14 cases. However, targets were only breached by two cases, meaning only £20,000 in fines was avoided. Deducting this from the total costs of the MDT-RCA meant the Trust lost £3,795.74-£31,670.10. Over the two years reviewed, the MDT-RCA proved to be costly to the Trust, with no additional learning or quality improvement measures identified.

Ocorrência do ácaro vermelho europeu Panonychus ulmi (Koch (Tetranychidae associado à cultura da videira no Rio Grande do Sul, Brasil European red spider mite Panonychus ulmi (Koch (Tetranychidae occurrence of vineyards in Rio Grande do Sul, Brazil

Directory of Open Access Journals (Sweden)

Noeli Juarez Ferla

2008-09-01

Full Text Available Neste artigo é descrita ocorrência e o dano causado pelo ácaro vermelho europeu Panonychus ulmi (Koch associado à cultura da videira. As coletas foram realizadas na safra 2005-2006 em Vitis vinifera L. da cultivar Merlot, nos municípios de Bento Gonçalves e Candiota, no Estado do Rio Grande do Sul, Brasil. As folhas infestadas apresentaram bronzeamento, com manchas avermelhadas na face adaxial, resultando na queda prematura das mesmas. Esse é o primeiro registro do ácaro vermelho europeu danificando a cultura da videira no Rio Grande do Sul.The occurrence and the damage caused for the European red spider mite Panonychus ulmi (Koch associated to the culture of the grapevine are described. The collections had been carried through in 2005-2006 seasons in Vitis vinifera L. of cultivating Merlot in Bento Gonçalves and Candiota counties, in the state of Rio Grande do Sul, Brazil. The infested leaves had presented bronzing, with spots redly in the adaxial face resulting in the premature fall. This is the first register of the European red mite damaging the culture of the grapevine in Rio Grande do Sul.

A Sociobiological Analysis Of Resource Control Issues | Nnadi ...

African Journals Online (AJOL)

Adopting the stand point that humans are part of the animal kingdom, the sociobiological phenomena of metamorphosis, aggression and territoriality are introduced into the fray. They are then juxtaposed to the issue of resource control and applied to improve understanding and, hopefully, management of the former.

Enhancing the competitiveness of an SMME in the automotive industry through the introduction of laser based manufacturing. A case study

CSIR Research Space (South Africa)

Burger, HP

2006-01-01

Full Text Available to synthetic fibre the cut is produced by melting the individual fibres resulting in a semi sealed cut edge that is totally free of fraying and lint. This paper illustrates how the introduction of laser cutting into the manufacturing process not only solved...

La historia sacra del Santísimo Sacramento contra las heregias destos tiempos"An iconographic study of the engravings illustrating the work

Directory of Open Access Journals (Sweden)

Calvo Portela, Juan Isaac

2014-01-01

Full Text Available En este artículo se hace un estudio iconográfico de las dos estampas que ilustran el libro del dominico fray Alonso de Ribera, La Historia Sacra del Santissimo Sacramento contra las heregias destos tiempos, editado por Luis Sánchez en Madrid en 1626. En dichas estampas se plasman dos aspectos que van a ser fundamentales de la religiosidad contrarreformista española del siglo XVII, la defensa a ultranza de la Eucaristía y la lucha contra la herejía. In this article is made an iconographic study of the two prints that illustrate the book of the Dominican Fray Alonso de Ribera, La Historia Sacra del Santissimo Sacramento contra las heregias destos tiempos, edited by Luis Sanchez in Madrid in 1626. In these prints are reflected two aspects that are going to be essential on the religiosity Spanish Counterreform of the seventeenth century, the stubborn defense of the Eucharist and the fight against heresy.

Rotastenting in an anomalously arising right coronary artery after an ugly dissection

Directory of Open Access Journals (Sweden)

Ashwin B. Mehta

2013-07-01

Full Text Available Rotational atherectomy is contraindicated in dissected coronary arteries since it can lead to progression of the dissection or perforation. In our case, the right coronary artery (RCA arose anomalously from the left coronary sinus. The lesion in the RCA was an undilatable calcified one. There was a dissection in the RCA due to high pressure balloon dilatation. Since the patient was hemodynamically unstable and there were no options besides rotablation, we proceeded with caution. Rotablation and stenting were successfully done. Our case report highlights the importance of the need for good guide catheter support even in the presence of anomalously arising arteries and the rotablation option for unyielding calcified coronary lesions, even in the setting of a dissection.

Characterization of Rubisco activase from thermally contrasting genotypes of Acer rubrum (Aceraceae).

Science.gov (United States)

Weston, David J; Bauerle, William L; Swire-Clark, Ginger A; Moore, Brandon D; Baird, Wm Vance

2007-06-01

The lability of Rubisco activase function is thought to have a major role in the decline of leaf photosynthesis under moderate heat (RCA1 and RCA2 proteins increased modestly in FL plants under warmer temperature, while only RCA2 protein increased in MN plants. Rubisco large subunit (RbsL) protein abundance was relatively unaffected in either genotype by temperature. These results support the idea that Rubisco activase, particularly the ratio of Rubisco activase to Rubisco, may play a role in the photosynthetic heat acclimation in A. rubrum and may have adaptive significance. This mechanism alone is not likely to entirely explain the thermotolerance in the FL genotype, and future research on adaptive mechanisms to high temperatures should consider activase function in a multipathway framework.

Brane-world cosmology and inflation

Indian Academy of Sciences (India)

A Lukas and D Skinner, J. High Energy Phys. 0109, 020 (2001). M C Bento, O Bertolami and A A Sen, Phys. Rev. D67, 063511 (2003). [8] J Garriga and M Sasaki, Phys. Rev. D62, 043523 (2000). [9] K Koyama and J Soda, Phys. Lett. B483, 432 (2000). [10] S Kanno, M Sasaki and J Soda, Prog. Theor. Phys. 109, 357 (2003).

Behaviour of Recycled Coarse Aggregate Concrete: Age and Successive Recycling

Science.gov (United States)

Sahoo, Kirtikanta; Pathappilly, Robin Davis; Sarkar, Pradip

2016-06-01

Recycled Coarse Aggregate (RCA) concrete construction technique can be called as `green concrete', as it minimizes the environmental hazard of the concrete waste disposal. Indian standard recommends target mean compressive strength of the conventional concrete in terms of water cement ratio ( w/ c). The present work is an attempt to study the behaviour of RCA concrete from two samples of parent concrete having different age group with regard to the relationship of compressive strength with water cement ratios. Number of recycling may influence the mechanical properties of RCA concrete. The influence of age and successive recycling on the properties such as capillary water absorption, drying shrinkage strain, air content, flexural strength and tensile splitting strength of the RCA concrete are examined. The relationship between compressive strength at different w/ c ratios obtained experimentally is investigated for the two parameters such as age of parent concrete and successive recycling. The recycled concrete using older recycled aggregate shows poor quality. While the compressive strength reduces with successive recycling gradually, the capillary water absorption increases abruptly, which leads to the conclusion that further recycling may not be advisable.

Computed microtomography visualization and quantification of mouse ischemic brain lesion by nonionic radio contrast agents.

Science.gov (United States)

Dobrivojević, Marina; Bohaček, Ivan; Erjavec, Igor; Gorup, Dunja; Gajović, Srećko

2013-02-01

To explore the possibility of brain imaging by microcomputed tomography (microCT) using x-ray contrasting methods to visualize mouse brain ischemic lesions after middle cerebral artery occlusion (MCAO). Isolated brains were immersed in ionic or nonionic radio contrast agent (RCA) for 5 days and subsequently scanned using microCT scanner. To verify whether ex-vivo microCT brain images can be used to characterize ischemic lesions, they were compared to Nissl stained serial histological sections of the same brains. To verify if brains immersed in RCA may be used afterwards for other methods, subsequent immunofluorescent labeling with anti-NeuN was performed. Nonionic RCA showed better gray to white matter contrast in the brain, and therefore was selected for further studies. MicroCT measurement of ischemic lesion size and cerebral edema significantly correlated with the values determined by Nissl staining (ischemic lesion size: P=0.0005; cerebral edema: P=0.0002). Brain immersion in nonionic RCA did not affect subsequent immunofluorescent analysis and NeuN immunoreactivity. MicroCT method was proven to be suitable for delineation of the ischemic lesion from the non-infarcted tissue, and quantification of lesion volume and cerebral edema.

Poverty, Inequality and the Future of Social Policy: Western States in the New World Order.

Science.gov (United States)

McFate, Katherine, Ed.; Lawson, Roger, Ed.; Wilson, William Julius, Ed.

This book analyzes forces fraying the social fabric of many countries, and the reasons why some Western countries have been more successful than others in addressing these trends. Part 1, "Poverty, Income Inequality, and Labor Market Insecurity: A Comparative Perspective," includes (1) "Markets and States: Poverty Trends and…

Redes produtivas : um estudo de caso da Associação Retirense de Apicultores em Barão de Melgaço - MT como altenativa de desenvolvimento regional Redes produtivas : um estudo de caso da Associação Retirense de Apicultores em Barão de Melgaço - MT como altenativa de desenvolvimento regional

Directory of Open Access Journals (Sweden)

Silvana Emanuelle Dotto

2008-12-01

Full Text Available This article consists on the study of how beekeeping can contribute to the economic development of small agricultural communities. The case study is the Retirense Association of Beekeepers (ARAPI established by inhabitants of the «Retiro São Bento» community, located in the «Pantanal» in the city Barão de Melgaço in Mato Grosso, Brazil. The objective is to study the structure of the productive net of this organization as well as its importance for the development of the region where it is inserted. The research has been based on observation in loco and in information in documents yielded by Association and Ecological Ranch «SESC Pantanal». This is the entity that promoted the first actions for the insertion of the beekeeping in the «Retiro São Bento» community. As it has been already pointed in some studies, the Pantanal is an ecosystem of beehive, and then, the ARAPI has gotten success in its production and consequently the community could increase the familiar income, and promote actions for the development of the beekeeping as well as to guarantee a longer time of the biological wealth of this environmental «pantaneiro» to the next generations.Este artigo constitui-se no estudo de como a apicultura pode contribuir para o desenvolvimento econômico de pequenas comunidades rurais, em especial no caso da Associação Retirense de Apicultores (ARAPI fundada por moradores da comunidade Retiro São Bento localizada no Pantanal do município de Barão de Melgaço em Mato Grosso. Tendo como objetivo estudar a estrutura da rede produtiva desta organização bem como sua importância para o desenvolvimento da região em que está inserida, os meios de investigação se basearam em observação in loco e coleta de informações em documentos cedidos pela Associação e pela estância Ecológica SESC Pantanal, entidade que promoveu as primeiras ações para a inserção da apicultura na comunidade Retiro São Bento. Como já apontado em

Training the next generation analyst using red cell analytics

Science.gov (United States)

Graham, Meghan N.; Graham, Jacob L.

2016-05-01

We have seen significant change in the study and practice of human reasoning in recent years from both a theoretical and methodological perspective. Ubiquitous communication coupled with advances in computing and a plethora of analytic support tools have created a push for instantaneous reporting and analysis. This notion is particularly prevalent in law enforcement, emergency services and the intelligence community (IC), where commanders (and their civilian leadership) expect not only a birds' eye view of operations as they occur, but a play-by-play analysis of operational effectiveness. This paper explores the use of Red Cell Analytics (RCA) as pedagogy to train the next-gen analyst. A group of Penn State students in the College of Information Sciences and Technology at the University Park campus of The Pennsylvania State University have been practicing Red Team Analysis since 2008. RCA draws heavily from the military application of the same concept, except student RCA problems are typically on non-military in nature. RCA students utilize a suite of analytic tools and methods to explore and develop red-cell tactics, techniques and procedures (TTPs), and apply their tradecraft across a broad threat spectrum, from student-life issues to threats to national security. The strength of RCA is not always realized by the solution but by the exploration of the analytic pathway. This paper describes the concept and use of red cell analytics to teach and promote the use of structured analytic techniques, analytic writing and critical thinking in the area of security and risk and intelligence training.

Analytically Sensitive Protein Detection in Microtiter Plates by Proximity Ligation with Rolling Circle Amplification.

Science.gov (United States)

Ebai, Tonge; Souza de Oliveira, Felipe Marques; Löf, Liza; Wik, Lotta; Schweiger, Caroline; Larsson, Anders; Keilholtz, Ulrich; Haybaeck, Johannes; Landegren, Ulf; Kamali-Moghaddam, Masood

2017-09-01

Detecting proteins at low concentrations in plasma is crucial for early diagnosis. Current techniques in clinical routine, such as sandwich ELISA, provide sensitive protein detection because of a dependence on target recognition by pairs of antibodies, but detection of still lower protein concentrations is often called for. Proximity ligation assay with rolling circle amplification (PLARCA) is a modified proximity ligation assay (PLA) for analytically specific and sensitive protein detection via binding of target proteins by 3 antibodies, and signal amplification via rolling circle amplification (RCA) in microtiter wells, easily adapted to instrumentation in use in hospitals. Proteins captured by immobilized antibodies were detected using a pair of oligonucleotide-conjugated antibodies. Upon target recognition these PLA probes guided oligonucleotide ligation, followed by amplification via RCA of circular DNA strands that formed in the reaction. The RCA products were detected by horseradish peroxidase-labeled oligonucleotides to generate colorimetric reaction products with readout in an absorbance microplate reader. We compared detection of interleukin (IL)-4, IL-6, IL-8, p53, and growth differentiation factor 15 (GDF-15) by PLARCA and conventional sandwich ELISA or immuno-RCA. PLARCA detected lower concentrations of proteins and exhibited a broader dynamic range compared to ELISA and iRCA using the same antibodies. IL-4 and IL-6 were detected in clinical samples at femtomolar concentrations, considerably lower than for ELISA. PLARCA offers detection of lower protein levels and increased dynamic ranges compared to ELISA. The PLARCA procedure may be adapted to routine instrumentation available in hospitals and research laboratories. © 2017 American Association for Clinical Chemistry.

Impact of aging on leaching characteristics of recycled concrete aggregate.

Science.gov (United States)

Abbaspour, Aiyoub; Tanyu, Burak F; Cetin, Bora

2016-10-01

The focus of this study was to evaluate the effects of stockpiling (aging) on leaching of elements in recycled concrete aggregate (RCA) that may contribute to tufaceous constituent formation. Speciation and leaching controlling mechanisms of these elements were identified via geochemical modeling. The effects of stockpiling were simulated by comparing freshly produced RCA with RCA aged as part of this study for 1 year both in the laboratory and in the field. Leachate samples were generated following batch water leach test (WLT) and US Geological Survey leach test (USGSLT) methods. USGSLTs were conducted both on the laboratory and field samples while WLT was only conducted on laboratory samples. During the laboratory aging, it is observed that the carbonate content of RCA, measured as calcite equivalent, increased 20 % (i.e., from ∼100 to 120 mg/g) within a year time frame. The leachate extracted from RCA showed minor changes in pH and more significant decreases in electrical conductivity (i.e., ∼300 to 100 μS/cm). A comparison between laboratory and field samples revealed that the RCA aged much slower in the field than in the laboratory within a year. Comparisons between two leach extraction methods on the laboratory conditions showed that the total leached concentrations (TLCs) of most of the constituents from USGSLT were appreciably lower than the ones measured via WLT method. The results of geochemical modeling analyses showed that Al, Si, Fe, Ca, Mg, and Cu exist in their oxidized forms as Al 3+ , Fe 3+ , Si 4+ , Ca 2+ , Mg 2+ , and Cu 2+ and results revealed that these elements are primarily controlled by the solubility of gibbsite, hematite, silica gel, calcite, magnesite, and tenorite solid phases, respectively. One of the significant findings of the study was to identify the changes in leaching behavior of Ca, Si, Mg, Al, Fe, and Cu due to carbonation.

Identifying and Overcoming Barriers to Effective Consideration of Human and Organisational Factors in Event Analysis and Root Cause Analysis. Workshop Proceedings, September 21-22, 2009, Paris, France

International Nuclear Information System (INIS)

2011-01-01

Nuclear licensees must have effective processes for learning from operating experience in order to manage safety, secure continuous improvement and defend against the potential for repeat events. These processes include root cause analysis (RCA) to identify the underlying causes of events and mechanisms to learn from these analyses and to implement improvements. Correctly identifying and correcting the causes of events will allow lessons to be learned and shared with others in the industry. The treatment of Human and Organisational Factors (HOF) in RCA is of special interest to WGHOF. It is estimated that approximately 60-80% of events in the nuclear industry can be attributed to human and organisational factors. Although the importance of correctly identifying the HOF causes is understood, there is still a tendency for the analysis to focus solely on the technical issues of the event. The history of prominent events across the major hazards sector shows that HOF lessons often fail to be learned. A NEA/CSNI special experts meeting entitled 'Identification of Barriers to Analyzing and Identifying Human and Organisational Factors in Root Cause Analysis' was held at the NEA Headquarters in Paris, France on September 21-22, 2009. A total of 17 participants from 10 countries representing licensee organisations, regulators, international organisations and an independent consultant attended the meeting. The meeting was structured to allow for small group discussions during which a number of themes were explored, followed by plenary discussion. There were also four papers presented which complemented the discussion themes. As set out in the objectives of this work, the participants identified barriers to the effective treatment of HOF in RCA and recommendations to mitigate the effects of these barriers. Many of the barriers and recommendations identified relate to the RCA process in general, not specifically to the treatment of HOF in the RCA process. This is logical, for

Comparison of three methods for detection of melamine in compost and soil

International Nuclear Information System (INIS)

Tian, Yongqiang; Chen, Liming; Gao, Lihong; Wu, Manli; Dick, Warren A.

2012-01-01

Recent product recalls and food safety incidents due to melamine (MM) adulteration or contamination have caused a worldwide food security concern. This has led to many methods being developed to detect MM in foods, but few methods haves been reported that can rapidly and reliably measure MM in environmental samples. To meet this need, a high performance liquid chromatography (HPLC) with UV detection method, an enzyme-linked immunosorbent assay (ELISA) test kit, and an enzyme-linked rapid colorimetric assay (RCA) test kit were evaluated for their ability to accurately measure MM concentrations in compost and soil samples. All three methods accurately detected MM concentrations if no MM degradation products, such as ammeline (AMN), ammelide (AMD) and cyanuric acid (CA), were present in an aqueous sample. In the presence of these MM degradation products, the HPLC yielded more accurate concentrations than the ELISA method and there was no significant (P > 0.05) difference between the HPLC and RCA methods. However, if samples were purified by SPE or prepared with blocking buffer, the ELISA method accurately measured MM concentrations, even in the presence of the MM degradation products. The HPLC method generally outperformed the RCA method for measuring MM in soil extracts but gave similar results for compost extracts. The number of samples that can be analyzed by the ELISA and RCA methods in a 24-hour time period is much greater than by the HPLC method. Thus the RCA method would seem to be a good screening method for measuring MM in compost and soil samples and the results obtained could then be confirmed by the HPLC method. The HPLC method, however, also allows simultaneous measurement of MM and its degradation products of AMD, AMN and CA. - Highlights: ► We detected melamine in environmental samples by three methods. ► ELISA can measures melamine in an environmental sample if a blocking buffer is used. ► A rapid colorimetric assay (RCA) rapidly screens

Rapid detection of ERG11 gene mutations in clinical Candida albicans isolates with reduced susceptibility to fluconazole by rolling circle amplification and DNA sequencing

Directory of Open Access Journals (Sweden)

Ellis David

2009-08-01

Full Text Available Abstract Background Amino acid substitutions in the target enzyme Erg11p of azole antifungals contribute to clinically-relevant azole resistance in Candida albicans. A simple molecular method for rapid detection of ERG11 gene mutations would be an advantage as a screening tool to identify potentially-resistant strains and to track their movement. To complement DNA sequencing, we developed a padlock probe and rolling circle amplification (RCA-based method to detect a series of mutations in the C. albicans ERG11 gene using "reference" azole-resistant isolates with known mutations. The method was then used to estimate the frequency of ERG11 mutations and their type in 25 Australian clinical C. albicans isolates with reduced susceptibility to fluconazole and in 23 fluconazole-susceptible isolates. RCA results were compared DNA sequencing. Results The RCA assay correctly identified all ERG11 mutations in eight "reference" C. albicans isolates. When applied to 48 test strains, the RCA method showed 100% agreement with DNA sequencing where an ERG11 mutation-specific probe was used. Of 20 different missense mutations detected by sequencing in 24 of 25 (96% isolates with reduced fluconazole susceptibility, 16 were detected by RCA. Five missense mutations were detected by both methods in 18 of 23 (78% fluconazole-susceptible strains. DNA sequencing revealed that mutations in non-susceptible isolates were all due to homozygous nucleotide changes. With the exception of the mutations leading to amino acid substitution E266D, those in fluconazole-susceptible strains were heterozygous. Amino acid substitutions common to both sets of isolates were D116E, E266D, K128T, V437I and V488I. Substitutions unique to isolates with reduced fluconazole susceptibility were G464 S (n = 4 isolates, G448E (n = 3, G307S (n = 3, K143R (n = 3 and Y123H, S405F and R467K (each n = 1. DNA sequencing revealed a novel substitution, G450V, in one isolate. Conclusion The sensitive RCA

Less increase of CT-based calcium scores of the coronary arteries. Effect three years after breast-conserving radiotherapy using breath-hold

Energy Technology Data Exchange (ETDEWEB)

Mast, M.E.; Kempen-Harteveld, M.L. van; Petoukhova, A.L. [Centre West, Radiotherapy, The Hague (Netherlands); Heijenbrok, M.W. [Medical Center Haaglanden, Department of Radiology, The Hague (Netherlands); Scholten, A.N. [Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital, Department of Radiation Oncology, Amsterdam (Netherlands); Wolterbeek, R. [Leiden University Medical Centre, Department of Medical Statistics and Bioinformatics, Leiden (Netherlands); Schreur, J.H.M. [Medical Center Haaglanden, Department of Cardiology, The Hague (Netherlands); Struikmans, H. [Centre West, Radiotherapy, The Hague (Netherlands); Leiden University Medical Centre, Department of Clinical Oncology, Leiden (Netherlands)

2016-10-15

The aim of this prospective longitudinal study was to compare coronary artery calcium (CAC) scores determined before the start of whole breast irradiation with those determined 3 years afterwards. Changes in CAC scores were analysed in 99 breast cancer patients. Three groups were compared: patients receiving left- and right-sided radiotherapy, and those receiving left-sided radiotherapy with breath-hold. We analysed overall CAC scores and left anterior descending (LAD) and right coronary artery (RCA) CAC scores. Between the three groups, changes of the value of the LAD minus the RCA CAC scores of each individual patient were also compared. Three years after breath-hold-based whole breast irradiation, a less pronounced increase of CAC scores was noted. Furthermore, LAD minus RCA scores in patients treated for left-sided breast cancer without breath-hold were higher when compared to LAD minus RCA scores of patients with right-sided breast cancers and those with left-sided breast cancer treated with breath-hold. Breath-hold in breast-conserving radiotherapy leads to a less pronounced increase of CT-based CAC scores. Therefore, breath-hold probably prevents the development of radiation-induced coronary artery disease. However, the sample size of this study is limited and the follow-up period relatively short. (orig.) [German] Das Ziel dieser prospektiven Langzeitstudie war der Vergleich der Coronary-Artery-Calcium-(CAC-)Werte vor Beginn der Brustbestrahlung mit den Werten nach 3 Jahren. Aenderungen der CAC-Werte wurden bei 99 Brustkrebspatienten analysiert. Drei Gruppen wurden untersucht: Patienten nach links- und rechtsseitiger Strahlentherapie sowie mit Bestrahlung unter Atemanhalt. Wir analysierten die Gesamt-CAC-Werte sowie die CAC-Werte der vorderen linken absteigenden (''left anterior descending'', LAD) und der rechten Koronararterie (''right coronary artery'', RCA). Zwischen den drei Gruppen wurden auch die Veraenderungen

The role and activity of the IAEA in the field of isotope use

International Nuclear Information System (INIS)

Kakihana, H.

1980-01-01

The Regional Cooperative Agreement (RCA) in Asia by IAEA entered into force in June, 1972, based on the period of every 5 years with the participation of Australia, India, Indonesia, Japan, Republic of Korea, Malaysia, Pakistan, Phillippine, Singapore and Thailand. The RCA aims to direct its technological efforts of using isotopes and radiation to the areas of highest regional interests, i.e. food and agriculture, health care, water resource management, environmental control and industrial development, along with upgrading the infrastructure to keep pace with technological advancements. The activities of the RCA in these fields are described as follows: food processing with ionizing radiation and the improvement of protein supplies, environment, hydrology and sedimentology, neutron scattering and nuclear instrument maintenance, UNDP regional project for industrial isotope and radiation applications. (J.P.N.)

The Myth of Rational Objectivity and Leadership: The Realities of a Hospital Merger from a CEO's Perspective

Science.gov (United States)

Tobin, John H.

2009-01-01

Executive power and status depends on others' belief in the executive's capacity for control via rational decision-making, "by the numbers" and above the fray of day to day minutia. By exploring his own experience in the complex social dynamics of a long, complicated merger process--characterised by misunderstanding, incomplete…

ANALISIS SISTEM PENETAPAN FRANCHISE FEE DAN ROYALTY FEE PADA FRANCHISE BRC

Directory of Open Access Journals (Sweden)

Walid Darmawan

2016-02-01

Full Text Available Pada saat ini bisnis franchise atau waralaba di indonesia, semakin menjamur dan banyak diminati oleh masyarakat untuk mencari peluang baru, dari mulai waralaba lokal seperti Ayam bakar Wong Solo, Es Teller 77, Burger Mr.Edam,Alfa Mart, Indomart dan lain-lain. Sampai waralaba mancanegarapun semakin banyak diminati seperti KFC, Mc.Donalds, Hoka-Hoka Bento, Starbuck Coffiee dan lain sebagainya.DOI: 10.15408/aiq.v2i1.2472

Analisis Sistem Penetapan Franchise Fee dan Royalty Fee pada Franchise Brc

OpenAIRE

Darmawan, Walid

2010-01-01

Pada saat ini bisnis franchise atau waralaba di indonesia, semakin menjamur dan banyak diminati oleh masyarakat untuk mencari peluang baru, dari mulai waralaba lokal seperti Ayam bakar Wong Solo, Es Teller 77, Burger Mr.Edam,Alfa Mart, Indomart dan lain-lain. Sampai waralaba mancanegarapun semakin banyak diminati seperti KFC, Mc.Donalds, Hoka-Hoka Bento, Starbuck Coffiee dan lain sebagainya.DOI: 10.15408/aiq.v2i1.2472

Fraying at the Edges: UK Surrogacy Law in 2015.

Science.gov (United States)

Horsey, Kirsty

2016-11-01

This commentary examines a series of high-profile surrogacy cases decided in 2015. Taken singly or together, these cases serve to illustrate how the UK's law on surrogacy—in particular its provisions regarding eligibility for parental orders—is not only out of date but also becoming nonsensical. These problems culminate in an evident inability of the law to protect the best interests of children born through surrogacy and indicate strongly a need for reform.

Community Laboratory Testing for Cryptosporidium: Multicenter Study Retesting Public Health Surveillance Stool Samples Positive for Cryptosporidium by Rapid Cartridge Assay with Direct Fluorescent Antibody Testing.

Directory of Open Access Journals (Sweden)

Dawn M Roellig

Full Text Available Cryptosporidium is a common cause of sporadic diarrheal disease and outbreaks in the United States. Increasingly, immunochromatography-based rapid cartridge assays (RCAs are providing community laboratories with a quick cryptosporidiosis diagnostic method. In the current study, the Centers for Disease Control and Prevention (CDC, the Association of Public Health Laboratories (APHL, and four state health departments evaluated RCA-positive samples obtained during routine Cryptosporidium testing. All samples underwent "head to head" re-testing using both RCA and direct fluorescence assay (DFA. Community level results from three sites indicated that 54.4% (166/305 of Meridian ImmunoCard STAT! positives and 87.0% (67/77 of Remel Xpect positives were confirmed by DFA. When samples were retested by RCA at state laboratories and compared with DFA, 83.3% (155/186 of Meridian ImmunoCard STAT! positives and 95.2% (60/63 of Remel Xpect positives were confirmed. The percentage of confirmed community results varied by site: Minnesota, 39.0%; New York, 63.9%; and Wisconsin, 72.1%. The percentage of confirmed community results decreased with patient age; 12.5% of community positive tests could be confirmed by DFA for patients 60 years of age or older. The percentage of confirmed results did not differ significantly by sex, storage temperature, time between sample collection and testing, or season. Findings from this study demonstrate a lower confirmation rate of community RCA positives when compared to RCA positives identified at state laboratories. Elucidating the causes of decreased test performance in order to improve overall community laboratory performance of these tests is critical for understanding the epidemiology of cryptosporidiosis in the United States (US.

Isolation of Resistance Gene Candidates (RGCs) and characterization of an RGC cluster in cassava.

Science.gov (United States)

López, C E; Zuluaga, A P; Cooke, R; Delseny, M; Tohme, J; Verdier, V

2003-08-01

Plant disease resistance genes (R genes) show significant similarity amongst themselves in terms of both their DNA sequences and structural motifs present in their protein products. Oligonucleotide primers designed from NBS (Nucleotide Binding Site) domains encoded by several R-genes have been used to amplify NBS sequences from the genomic DNA of various plant species, which have been called Resistance Gene Analogues (RGAs) or Resistance Gene Candidates (RGCs). Using specific primers from the NBS and TIR (Toll/Interleukin-1 Receptor) regions, we identified twelve classes of RGCs in cassava (Manihot esculenta Crantz). Two classes were obtained from the PCR-amplification of the TIR domain. The other 10 classes correspond to the NBS sequences and were grouped into two subfamilies. Classes RCa1 to RCa5 are part of the first subfamily and were linked to a TIR domain in the N terminus. Classes RCa6 to RCa10 corresponded to non-TIR NBS-LRR encoding sequences. BAC library screening with the 12 RGC classes as probes allowed the identification of 42 BAC clones that were assembled into 10 contigs and 19 singletons. Members of the two TIR and non-TIR NBS-LRR subfamilies occurred together within individual BAC clones. The BAC screening and Southern hybridization analyses showed that all RGCs were single copy sequences except RCa6 that represented a large and diverse gene family. One BAC contained five NBS sequences and sequence analysis allowed the identification of two complete RGCs encoding two highly similar proteins. This BAC was located on linkage group J with three other RGC-containing BACs. At least one of these genes, RGC2, is expressed constitutively in cassava tissues.

Recycled concrete aggregate as road base: Leaching constituents and neutralization by soil Interactions and dilution.

Science.gov (United States)

Gupta, Nautasha; Kluge, Matt; Chadik, Paul A; Townsend, Timothy G

2018-02-01

Recycled Concrete Aggregate (RCA) is often used as a replacement for natural aggregate in road construction activities because of its excellent mechanical properties, and this trend should increase as more transportation departments include RCA in specifications and design manuals. Concerns raised by some engineers and contractors include impacts from leachate generated by RCA, both from transport of metals to water sources and the impact of a high pH leachate on corrosion of underlying metal drainage pipes. In this study, RCA collected from various regions of Florida exhibited pH ranging from 10.5 to 12.3. Concentrations of Al, Ba, Cr, Fe, Mo, Na, Ni, Sb, and Sr measured using batch leaching tests exceeded applicable risk-based thresholds on at least some occasions, but the concentrations measured suggest that risk to water supplies should be controlled because of dilution and attenuation. Two mechanisms of pH neutralization were evaluated. Soil acidity plays a role, but laboratory testing and chemical modeling found that at higher liquid-to-solid ratios the acidity is exhausted. If high pH leachate did reach groundwater, chemical modeling indicated that groundwater dilution and carbonation would mitigate groundwater pH effects. Copyright © 2017 Elsevier Ltd. All rights reserved.

DNAzyme Feedback Amplification: Relaying Molecular Recognition to Exponential DNA Amplification.

Science.gov (United States)

Liu, Meng; Yin, Qingxin; McConnell, Erin M; Chang, Yangyang; Brennan, John D; Li, Yingfu

2018-03-26

Technologies capable of linking DNA amplification to molecular recognition are very desirable for ultrasensitive biosensing applications. We have developed a simple but powerful isothermal DNA amplification method, termed DNAzyme feedback amplification (DFA), that is capable of relaying molecular recognition to exponential DNA amplification. The method incorporates both an RNA-cleaving DNAzyme (RCD) and rolling circle amplification (RCA) carried out by a special DNA polymerase using a circular DNA template. DFA begins with a stimulus-dependent RCA reaction, producing tandemly linked RCDs in long-chain DNA products. These RCDs cleave an RNA-containing DNA sequence to form additional primers that hybridize to the circular DNA molecule, giving rise to DNA assemblies that act as the new inputs for RCA. The RCA reaction and the cleavage event keep on feeding each other autonomously, resulting in exponential growth of repetitive DNA sequences that can be easily detected. This method can be used for the detection of both nucleic acid based targets and non-nucleic acid analytes. In this article, we discuss the conceptual framework of the feedback amplification approach, the essential features of this method as well as remaining challenges and possible solutions. © 2018 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

Digital quantification of rolling circle amplified single DNA molecules in a resistive pulse sensing nanopore.

Science.gov (United States)

Kühnemund, M; Nilsson, M

2015-05-15

Novel portable, sensitive and selective DNA sensor methods for bio-sensing applications are required that can rival conventionally used non-portable and expensive fluorescence-based sensors. In this paper, rolling circle amplification (RCA) products are detected in solution and on magnetic particles using a resistive pulse sensing (RPS) nanopore. Low amounts of DNA molecules are detected by padlock probes which are circularized in a strictly target dependent ligation reaction. The DNA-padlock probe-complex is captured on magnetic particles by sequence specific capture oligonucleotides and amplified by a short RCA. Subsequent RPS analysis is used to identify individual particles with single attached RCA products from blank particles. This proof of concept opens up for a novel non-fluorescent digital DNA quantification method that can have many applications in bio-sensing and diagnostic approaches. Copyright © 2014 Elsevier B.V. All rights reserved.

Unusually Looped and Muzzled Branches of Right Coronary Artery

Directory of Open Access Journals (Sweden)

Anitha Guru

2017-01-01

Full Text Available Coronary artery disease (CAD is the major cause of death in developed countries as it accounts on an average for 1 of every 5 deaths. Morphological variations of coronary arterial system is one of the causative factor for CAD. Anatomical knowledge of all possible variant patterns of coronary arterial system is imperative in the diagnostic and therapeutic approach of CAD. We report here a rare branching pattern of right coronary artery (RCA. The origin of RCA was normal but the course and branching pattern of it were atypical. RCA was not occupying its usual position in atrioventricular (coronary sulcus and its course was incomplete. It gave a ventricular branch to right ventricle, which presented an unusual looping pattern. It terminated as right marginal artery following its muzzled appearance within the musculature of the ventricle.

Uma análise das características da estrutura de governança em sistemas locais de produção e suas relações com a cadeia global An analysis of the characteristics of the governance struture in local production systems and its relations with the global chain

Directory of Open Access Journals (Sweden)

Renato Garcia

2004-12-01

Full Text Available Este trabalho tem o objetivo de analisar, de forma integrada, a problemática da governança global e local em sistemas locais de produção, com o intuito de verificar os condicionantes para a competitividade dos produtores e o desenvolvimento local. Para isso, são investigadas e comparadas duas experiências de sistemas locais de produção no Brasil: a indústria de calçados de Franca (SP e a de móveis em Bento Gonçalves (RS. As principais evidências apontam que o desenvolvimento de capacitações entre os produtores localizados é condicionado pelas formas de governança, global e local, sobre a cadeia produtiva.This paper analyzes industrial clusters, characterizing and integrating the view of global and local governance and identifying the conditioning factors of producer competitiveness and local development. To this end, the paper investigates two Brazilian industrial clusters: the footwear industry in Franca, SP and the furniture industry in Bento Gonçalves, RS. The main findings show that the forms of global governance of the production chain are crucial conditioning factors of the development of capabilities among local producers.

Diversidad y el estado de conservación de cuerpos de agua Amazónicos en el nororiente del Perú

Directory of Open Access Journals (Sweden)

Hernán Ortega

2013-05-01

Full Text Available En el presente trabajo se describen la diversidad y estado de conservación, determinados por un inventario biológico rápido, entre el 24 y 30 de octubre de 2005, en cuerpos de agua del nororiente del Perú, ubicados, entre los 133 y 680 m de altitud, entre Tarapoto (San Martín y Yurimaguas (Loreto. Se colectaron datos y muestras en 26 estaciones. Los peces fueron colectados con redes de arrastre a la orilla, el bentos con red "Surber", y el plancton con red estándar (40 micras. En cada estación, se anotaron coordenadas (UTM y se describieron hábitats limnologicamente (pH, temperatura, conductividad, oxigeno disuelto. La riqueza de especies en peces fue de 95, predominan Characiformes y Siluriformes. La riqueza de especies de peces en fitoplancton fue de 74, en zooplancton, 22 especies y en bentos de 20 especies. Para determinar el estado de conservación se uso el Índice de Integridad Biológica (IBI para peces y EPT (Ephemeroptera, Plecoptera, y Trichoptera para la integridad de los ambientes acuáticos. Los resultados indican que en las zonas mejor conservadas se encuentran en los alrededores de Yurimaguas.

Properties of high-workability concrete with recycled concrete aggregate

OpenAIRE

Safiuddin,; Alengaram,Ubagaram Johnson; Salam,Abdus; Jumaat,Mohd Zamin; Jaafar,Fahrol Fadhli; Saad,Hawa Binti

2011-01-01

This study presents the effects of recycled concrete aggregate (RCA) on the key fresh and hardened properties of concrete. RCA was used to produce high-workability concrete substituting 0-100% natural coarse aggregate (NCA) by weight. The slump and slump flow of fresh concretes were determined to ensure high workability. In addition, the compressive, flexural and splitting tensile strengths, modulus of elasticity, and permeable voids of hardened concretes were determined. The test results rev...

[Inhibition by cysteine of the carbohydrate-binding activity of lectins from Ricinus communis, Canavalia ensiformis and Euonymus europaeus].

Science.gov (United States)

Dvorkin, V M

1985-10-01

Precipitation induced by different lectins has been studied in the presence of some aminoacids. It was shown that precipitates formed by lectins from Ricinus communis (RCA1), Canavalia ensiformis (Con A), Euonymus europaeus (Eel) in the presence of appropriate carbohydrate-containing molecules disappeared after cysteine addition, like after addition of specific carbohydrate precipitation inhibitors. It is assumed that cysteine residues of RCA1, Con A and Eel lectins are essential for their carbohydrate binding activity.

How often do surgeons intervene on shoulder labral lesions detected at MR examination? A retrospective review of MR examinations correlated with arthroscopy

Science.gov (United States)

2014-01-01

Objective: We report the prevalence of surgical intervention on shoulder labral lesions detected at MR examinations and how surgeons describe labral tears seen at MR examinations in their arthroscopy reports. Methods: A retrospective review of 100 consecutive patients aged 50 years or younger who had shoulder labral tears on MR and went on to have surgery performed. It was determined whether surgical intervention was performed on the MR lesions. Results: Of these 100 patients, 72 had superior labral anterior to posterior (SLAP) tears, 38 had posterior labral tears and 28 had anterior labral tears on MR examination. All 100 patients went on to arthroscopy. All lesions described on MRI were described on arthroscopy. Of the 72 SLAP tears, 64 were described as fraying on arthroscopy with 51 debrided. The remaining eight SLAP tears were tacked surgically. Of the 38 posterior labral tears, 36 were described as fraying on arthroscopy with 29 debrided and 2 had surgical tacking performed. Of the 28 anterior labral tears described on MR examination, 26 had surgical tacking performed and 2 were debrided. There were four SLAP tears, two anterior labral tears and three posterior labral tears seen on arthroscopy but not seen on MR examination. Conclusion: In this series, a high percentage of SLAP tears and posterior labral tears described on MR examination did not have surgical tacking. Most anterior labral tears had surgical tacking. Based on the above, our surgeons request we describe superior and posterior labral lesions as fraying and/or tearing, unless we can see a displaced tear. Most anterior labral lesions are treated with surgical tacking. Advances in knowledge: MRI allows for sensitive detection of labral tears. The tears often are not clinically significant. PMID:24712320

Making the Most of Presidential Transitions

Science.gov (United States)

Marchese, Theodore J.

2012-01-01

The time between a president's resignation and the next president's assumption of office--often a 12-to-18 month period--can be crucial for an institution. Between the winding down of an existing presidency and the successful launch of the next, there are all too many opportunities for lost momentum, frayed relationships, key departures, and…

Beyond the "Ivory Tower": Restoring the Balance of Private and Public Purposes of General Education

Science.gov (United States)

Cantor, Nancy; Englot, Peter

2013-01-01

We in higher education have allowed the balance of the private and public purposes of liberal education to become skewed in our angst over fully embracing a central role in restoring prosperity and preparing our increasingly diverse population for the evolving responsibility of mending our fraying democracy. As we consider how best to reshape…

KI~I)ERS I~ ~ILITERE VERI3A~1)

African Journals Online (AJOL)

dat hy te oud vir trompetblaser geword het. Hy kwalifiseer as Gesondheidsinspekteur en attesteer op 2 Junie 1944 weer by die Suid-. Afrikaanse Weermag om as Vrywilliger in. Wereldoorlog 1/ diens te doen. Hy word op. 17 Mei 1946 met die rang van sersant gede- mobiliseer. Op 70-jarige leeftyd tree Fray as Hoofgesond-.

Textural parameters distribution in sediments surface of the Uruguay river background between km 221 and 254

International Nuclear Information System (INIS)

Capeluto, W.; Campos, T. de los

2010-01-01

The aim of this paper is to analyze the distribution of textural statistical parameters and spatial variation in the morphology of the sediment areas. The geology of the area comprises alluvial and alluvial deposits of variable thicknesses overlying deposits of Fray Bent os, Salto and Guichon formations that occasionally emerge in the river bed

Snake population venomics and antivenomics of Bothrops atrox: Paedomorphism along its transamazonian dispersal and implications of geographic venom variability on snakebite management

OpenAIRE

Calvete, Juan J.; Sanz, Libia; Pérez, Alicia; Borges, Adolfo; Vargas, Alba M.; Lomonte, Bruno; Angulo, Yamileth; Gutiérrez, José María; Chalkidis, Hipócrates M.; Mourão, Rosa H.V.; Furtado, María de Fátima; Moura Da Silva, Ana M.

2011-01-01

We describe two geographically differentiated venom phenotypes across the wide distribution range of Bothrops atrox, from the Colombian Magdalena Medio Valley through Puerto Ayacucho and El Paují, in the Venezuelan States of Amazonas and Orinoquia, respectively, and São Bento in the Brazilian State of Maranhão. Colombian and Venezuelan venoms show an ontogenetic toxin profile phenotype whereas Brazilian venoms exhibit paedomorphic phenotypes. Venoms from each of the 16 localities sampled cont...

Comparison of three methods for detection of melamine in compost and soil

Energy Technology Data Exchange (ETDEWEB)

Tian, Yongqiang [Depatment of Vegetable Science, College of Agronomy and Biotechnology, China Agricultural University, 2 Yuanmingyuan Xilu, Beijing 100193 (China); School of Environment and Natural Resources, The Ohio State University, 1680 Madison Avenue, Wooster, OH 44691 (United States); Chen, Liming [School of Environment and Natural Resources, The Ohio State University, 1680 Madison Avenue, Wooster, OH 44691 (United States); Gao, Lihong [Depatment of Vegetable Science, College of Agronomy and Biotechnology, China Agricultural University, 2 Yuanmingyuan Xilu, Beijing 100193 (China); Wu, Manli [School of Environment and Natural Resources, The Ohio State University, 1680 Madison Avenue, Wooster, OH 44691 (United States); School of Environmental and Municipal Engineering, Xi' an University of Architecture and Technology, No.13 Yanta Road, Xi' an, Shaanxi Province 710055 (China); Dick, Warren A., E-mail: dick.5@osu.edu [School of Environment and Natural Resources, The Ohio State University, 1680 Madison Avenue, Wooster, OH 44691 (United States)

2012-02-15

Recent product recalls and food safety incidents due to melamine (MM) adulteration or contamination have caused a worldwide food security concern. This has led to many methods being developed to detect MM in foods, but few methods haves been reported that can rapidly and reliably measure MM in environmental samples. To meet this need, a high performance liquid chromatography (HPLC) with UV detection method, an enzyme-linked immunosorbent assay (ELISA) test kit, and an enzyme-linked rapid colorimetric assay (RCA) test kit were evaluated for their ability to accurately measure MM concentrations in compost and soil samples. All three methods accurately detected MM concentrations if no MM degradation products, such as ammeline (AMN), ammelide (AMD) and cyanuric acid (CA), were present in an aqueous sample. In the presence of these MM degradation products, the HPLC yielded more accurate concentrations than the ELISA method and there was no significant (P > 0.05) difference between the HPLC and RCA methods. However, if samples were purified by SPE or prepared with blocking buffer, the ELISA method accurately measured MM concentrations, even in the presence of the MM degradation products. The HPLC method generally outperformed the RCA method for measuring MM in soil extracts but gave similar results for compost extracts. The number of samples that can be analyzed by the ELISA and RCA methods in a 24-hour time period is much greater than by the HPLC method. Thus the RCA method would seem to be a good screening method for measuring MM in compost and soil samples and the results obtained could then be confirmed by the HPLC method. The HPLC method, however, also allows simultaneous measurement of MM and its degradation products of AMD, AMN and CA. - Highlights: Black-Right-Pointing-Pointer We detected melamine in environmental samples by three methods. Black-Right-Pointing-Pointer ELISA can measures melamine in an environmental sample if a blocking buffer is used. Black

Curvilinear 3-D Imaging Using Row--Column-Addressed 2-D Arrays with a Diverging Lens: Feasibility Study

DEFF Research Database (Denmark)

Bouzari, Hamed; Engholm, Mathias; Beers, Christopher

2017-01-01

imaging. Extended FOV and low channel count of double-curved RCA 2-D arrays make 3-D imaging possible with equipment in the price range of conventional 2-D imaging. This study proposes a delay-and-sum beamformation scheme specific to double-curved RCA 2-D arrays and validates its focusing ability based...... of this study demonstrate that the proposed beamforming approach is accurate for achieving correct time-of-flight calculations, and hence avoids geometrical distortions....

Methods of Hydrographic Surveying Used by Different Countries.

Science.gov (United States)

1983-03-01

Numbers are averages for antenna variations in horizontal plane of 0-800. ARGO AFETR /RCA 19Bm RSS position error for 170 rumple APL/JHU points using...lower Chesapeake Bay network. Raydist-T AFETR /RCA 27m RSS fix accuracy, compared to Autotope, APL/JHU for 115 samples. Strong susceptibility to... effect is overcome by simply increasing the length between successive fixes -- instead of fixing every 3 meters, fix every 3.1 meters then every 3.2

Integration of Tax Administration to Curb Import and Domestic Tax Evasions in Ghana

OpenAIRE

John Adu Kwame; Eric Tutu Tchao; Kwasi Poku

2013-01-01

As part of the Government of Ghana’s plans to maximize tax mobilization, it recently integrated its Regional Collection Agencies (RCA) namely; the Internal Revenue Service (IRS), Customs Excise and Preventive service (CEPS) and the Value Added Tax (VAT) Services into the Ghana Revenue Authority (GRA). This research aims to find out whether Ghana’s tax administration reform of integrating the RCA into GRA has dealt with the inefficiencies in tax administration with respect to personal income t...

ST-depression in right precordial leads with inferior STEMI and occluded right coronary artery: intertwined anatomy and ischemic areas.

Science.gov (United States)

De Gennaro, Luisa; Brunetti, Natale Daniele; Ruggiero, Massimo; Rutigliano, David; Locuratolo, Nicola; Di Biase, Matteo; Caldarola, Pasquale

2017-10-01

Right coronary artery (RCA) occlusion in inferior acute myocardial infarction is usually heralded by ST-elevation both in inferior and in right precordial leads. We report the case of a 68-year-old male, who presented marked ST-elevation in inferior leads, mirrored by ST-depression in anterior-septal and lateral leads. Right precordial lead electrocardiogram unexpectedly showed ST-depression V1R-V5R leads. Coronary angiography showed mid-left anterior descending (LAD) coronary near-complete occlusion with distal wrapping LAD. Left circumflex artery was not occluded, while RCA was occluded mid tract. The patient was treated with coronary angioplasty on RCA and LAD. Absence of ST-elevation in right precordial leads may be presumably explained by the presence of a large ischemic area distal to mid-LAD near-occlusive stenosis and of a long-wrapping LAD. Complex coronary anatomy and intertwined ischemic areas may underlie apparently discording electrocardiograms.

Reliability and utility of citizen science reef monitoring data collected by Reef Check Australia, 2002-2015.

Science.gov (United States)

Done, Terence; Roelfsema, Chris; Harvey, Andrew; Schuller, Laura; Hill, Jocelyn; Schläppy, Marie-Lise; Lea, Alexandra; Bauer-Civiello, Anne; Loder, Jennifer

2017-04-15

Reef Check Australia (RCA) has collected data on benthic composition and cover at >70 sites along >1000km of Australia's Queensland coast from 2002 to 2015. This paper quantifies the accuracy, precision and power of RCA benthic composition data, to guide its application and interpretation. A simulation study established that the inherent accuracy of the Reef Check point sampling protocol is high (<±7% error absolute), in the range of estimates of benthic cover from 1% to 50%. A field study at three reef sites indicated that, despite minor observer- and deployment-related biases, the protocol does reliably document moderate ecological changes in coral communities. The error analyses were then used to guide the interpretation of inter-annual variability and long term trends at three study sites in RCA's major 2002-2015 data series for the Queensland coast. Copyright © 2017 Elsevier Ltd. All rights reserved.

Browse Title Index

African Journals Online (AJOL)

Items 451 - 500 of 789 ... Vol 38, No 1 (2015), On the inertia groups of the maximal subgroup 27:Sp6(2) in Aut(Fi22), Abstract. R.L. Fray, A.L. Prins. Vol 32, No 1 (2009), On the interlacing of zeros of linear combinations of Jacobi polynomials from different sequences, Abstract. Kathy Driver, Kerstin Jordaan, Norbert Mbuyi.

Retóricas del viaje a España, 1800-1900

Directory of Open Access Journals (Sweden)

Beatriz Colombi

2014-06-01

Full Text Available Partiendo de una reflexión crítica en torno a la literatura de viajes, se analizan los textos de Fray Servando, Sarmiento, Rubén Darío y Alfonso Reyes, para observar en ellos las relaciones que se establecen entre el viajero y, en este caso, España (expectativas, representaciones, descubrimientos.

Testing and Results of Vacuum Swing Adsorption Units for Spacesuit Carbon Dioxide and Humidity Control

Science.gov (United States)

McMillin, Summer D.; Broerman, Craig D.; Swickrath, Michael; Anderson, Molly

2011-01-01

A principal concern for extravehicular activity (EVA) spacesuits is the capability to control carbon dioxide (CO2) and humidity (H2O) for the crewmember. The release of CO2 in a confined or unventilated area is dangerous for human health and leads to asphyxiation; therefore, CO2 and H2O control become leading factors in the design and development of the spacesuit. An amine-based CO2 and H2O vapor sorbent for use in pressure-swing regenerable beds has been developed by Hamilton Sundstrand. The application of solidamine materials with vacuum swing adsorption technology has shown the capacity to concurrently manage CO2 and H2O levels through a fully regenerative cycle eliminating mission constraints imposed with nonregenerative technologies. Two prototype solid amine-based systems, known as rapid cycle amine (RCA), were designed to continuously remove CO2 and H2O vapor from a flowing ventilation stream through the use of a two-bed amine based, vacuum-swing adsorption system. The Engineering and Science Contract Group (ESCG) RCA implements radial flow paths, whereas the Hamilton Sundstrand RCA was designed with linear flow paths. Testing was performed in a sea-level pressure environment and a reduced-pressure environment with simulated human metabolic loads in a closed-loop configuration. This paper presents the experimental results of laboratory testing for a full-size and a sub-scale test article. The testing described here characterized and evaluated the performance of each RCA unit at the required Portable Life Support Subsystem (PLSS) operating conditions. The test points simulated a range of crewmember metabolic rates. The experimental results demonstrated the ability of each RCA unit to sufficiently remove CO2 and H2O from a closed loop ambient or sub-ambient atmosphere.

Overview of studies on the effect of recycled aggregates sourced from tested cylinders on concrete material and structural properties

Directory of Open Access Journals (Sweden)

Bilal Hamad

2017-01-01

Full Text Available The paper presents an overview of a two-phase research program that was designed at the American University of Beirut (AUB to investigate the effect of replacing different percentages of natural coarse aggregates (NCA with recycled coarse aggregates (RCA on the properties of the produced concrete. The source of RCA was tested cylinders in batching plants which would help recycling and reusing portion of the waste products of the concrete industry. In the first phase, the fresh and hardened mechanical properties of the produced concrete mix were investigated. The variables were the concrete strength (28 or 60 MPa and the percentage replacement of NCA with RCA from crushed tested cylinders [0 (control, 20, 40, 60, 80, or 100%. Normal strength tested cylinders were used as source of the recycled aggregates for the normal strength concrete (NSC mix and high strength tested cylinders were used for the high strength concrete (HSC mix. Tests included plastic state slump and hardened state mechanical properties including cylinder compressive strength, cylinder splitting tensile strength, modulus of elasticity, and standard beams flexural strength. The results indicated no significant effect on the slump and around 10% average reduction in the hardened mechanical properties for both investigated levels of concrete compressive strength. In the second phase, the structural behavior of normal strength concrete (NSC reinforced concrete beams prepared by replacing different percentages of NCA with RCA from tested concrete cylinders was studied. For each of three modes of failure (flexural, shear, or bond splitting, three beams with different percentages replacement [0 (control, 40, or 100 percent] were tested. One replicate was prepared for each beam to validate the test results. Results indicated no significant difference in the ultimate load reached or load-deflection behavior that could be related to the percentage replacement of NCA with RCA.

Recycled construction and demolition concrete waste as aggregate for structural concrete

Directory of Open Access Journals (Sweden)

Ashraf M. Wagih

2013-12-01

Full Text Available In major Egyptian cities there is a surge in construction and demolition waste (CDW quantities causing an adverse effect on the environment. The use of such waste as recycled aggregate in concrete can be useful for both environmental and economical aspects in the construction industry. This study discusses the possibility to replace natural coarse aggregate (NA with recycled concrete aggregate (RCA in structural concrete. An investigation into the properties of RCA is made using crushing and grading of concrete rubble collected from different demolition sites and landfill locations around Cairo. Aggregates used in the study were: natural sand, dolomite and crushed concretes obtained from different sources. A total of 50 concrete mixes forming eight groups were cast. Groups were designed to study the effect of recycled coarse aggregates quality/content, cement dosage, use of superplasticizer and silica fume. Tests were carried out for: compressive strength, splitting strength and elastic modulus. The results showed that the concrete rubble could be transformed into useful recycled aggregate and used in concrete production with properties suitable for most structural concrete applications in Egypt. A significant reduction in the properties of recycled aggregate concrete (RAC made of 100% RCA was seen when compared to natural aggregate concrete (NAC, while the properties of RAC made of a blend of 75% NA and 25% RCA showed no significant change in concrete properties.

Toxicity and environmental and economic performance of fly ash and recycled concrete aggregates use in concrete: A review.

Science.gov (United States)

Kurda, Rawaz; Silvestre, José D; de Brito, Jorge

2018-04-01

This paper presents an overview of previous studies on the environmental impact (EI) and toxicity of producing recycled concrete aggregates (RCA), fly ash (FA), cement, superplasticizer, and water as raw materials, and also on the effect of replacing cement and natural aggregates (NA) with FA and RCA, respectively, on the mentioned aspects. EI and toxicity were analysed simultaneously because considering concrete with alternative materials as sustainable depends on whether their risk assessment is high. Therefore, this study mainly focuses on the cradle-to-gate EI of one cubic meter of concrete, namely abiotic depletion potential (ADP), global warming potential (GWP), ozone depletion potential (ODP), photochemical ozone creation (POCP), acidification potential (AP), eutrophication potential (EP), non-renewable energy (PE-NRe) and renewable energy (PE-Re). In terms of toxicity, leachability (chemical and ecotoxicological characterization) was considered. The results also include the economic performance of these materials, and show that the incorporation of FA in concrete significantly decreases the EI and cost of concrete. Thus, the simultaneous incorporation of FA and RCA decrease the EI, cost, use of landfill space and natural resources extraction. Nonetheless, the leaching metals of FA decrease when they are incorporated in concrete. Relative to FA, the incorporation of RCA does not significantly affect the EI and cost of concrete, but it significantly reduces the use of landfill space and the need of virgin materials.

Report on the workshop to review waste inventory, waste characteristics and reference site candidates

International Nuclear Information System (INIS)

1997-07-01

There is a need of co-operation among Regional Co-operative Agreement (RCA) Member States in the field of low and intermediate level waste (LILW) disposal. An integrated approach is essential for successful establishment of LILW disposal facilities in RCA Member States. This would include: a) identification of waste inventory and characteristics; b) guidelines for implementation of LILW disposal; c) regulatory guidelines; d) safety assessment; e) quality assurance; and f) public acceptance. This project will focus on technical issues. The overall objective of the project, established in the project formulation meeting, is to assist RCA Member States in establishing national disposal activities for radioactive waste from nuclear applications by providing expert advice and training on techniques and methodology associated with planning and establishment of disposal facilities and to obtain improved knowledge of key staff members for the implementation of LILW disposal. The purpose of this workshop was to identify waste inventories, waste characteristics, site characteristics (generic or site specific) for disposal of LILW in RCA Member States of the project and identify conceptual reference site conditions and consider reference repository concepts preliminarily. Also the workshop was to establish an action plan of the next step. The workshop was held in Shanghai, China from 7 to 9 July 1997 and attended by 7 countries, i.e. Australia, China, Indonesia, Japan, Republic of Korea, Sri Lanka and Thailand. Refs, figs, tabs

Low Power S-Box Architecture for AES Algorithm using Programmable Second Order Reversible Cellular Automata: An Application to WBAN.

Science.gov (United States)

Gangadari, Bhoopal Rao; Ahamed, Shaik Rafi

2016-12-01

In this paper, we presented a novel approach of low energy consumption architecture of S-Box used in Advanced Encryption Standard (AES) algorithm using programmable second order reversible cellular automata (RCA 2 ). The architecture entails a low power implementation with minimal delay overhead and the performance of proposed RCA 2 based S-Box in terms of security is evaluated using the cryptographic properties such as nonlinearity, correlation immunity bias, strict avalanche criteria, entropy and also found that the proposed architecture is secure enough for cryptographic applications. Moreover, the proposed AES algorithm architecture simulation studies show that energy consumption of 68.726 nJ, power dissipation of 3.856 mW for 0.18- μm at 13.69 MHz and energy consumption of 29.408 nJ, power dissipation of 1.65 mW for 0.13- μm at 13.69 MHz. The proposed AES algorithm with RCA 2 based S-Box shows a reduction power consumption by 50 % and energy consumption by 5 % compared to best classical S-Box and composite field arithmetic based AES algorithm. Apart from that, it is also shown that RCA 2 based S-Boxes are dynamic in nature, invertible, low power dissipation compared to that of LUT based S-Box and hence suitable for Wireless Body Area Network (WBAN) applications.

Requirements of cyclin a for mitosis are independent of its subcellular localization.

Science.gov (United States)

Dienemann, Axel; Sprenger, Frank

2004-06-22

Cyclin A (CycA), the only essential mitotic cyclin in Drosophila, is cytoplasmic during interphase and accumulates in the nucleus during prophase. We show that interphase localization is mediated by Leptomycin B (LMB)-sensitive nuclear export. This is a feature shared with human CyclinB1, and it is assumed that nuclear accumulation is necessary for mitotic entry. Here, we tested if the unique mitotic function of CycA requires nuclear accumulation. We fused subcellular localization signals to CycA and tested their mitotic capability. Surprisingly, nuclear accumulation was not required, and even a membrane-tethered form of CycA was able to induce mitosis. We noted that Cyclin B (CycB) protein disappears prematurely in CycA mutants, reminiscent of rca1 mutants. Rca1 is an inhibitor of Fizzy-related-APC/C activity, and in rca1 mutants, mitotic cyclins are degraded in G2 of the 16(th) embryonic cell cycle. Overexpression of Rca1 can restore mitosis in CycA mutants, indicating that the mitotic failure of CycA mutants is caused by premature activation of the APC/C. The essential mitotic function of CycA is therefore not the activation of numerous mitotic substrates by Cdk1-dependent phosphorylation. Rather, CycA-dependent kinase activity is required to inhibit one inhibitor of mitosis, the Fzr protein.

Individualized radiation dose control in 256-slice CT coronary angiography (CTCA) in retrospective ECG-triggered helical scans: Using a measure of body size to adjust tube current selection

Energy Technology Data Exchange (ETDEWEB)

Li, Jing-Lei, E-mail: lijinglei80@126.com [Department of Radiology, Guangdong Academy of Medical Sciences, Guangdong General Hospital, 106 Zhongshan Er Road, Guangzhou 510080 (China); Huang, Mei-Ping, E-mail: huang_meiping@yahoo.com.cn [Department of Radiology, Guangdong Academy of Medical Sciences, Guangdong General Hospital, 106 Zhongshan Er Road, Guangzhou 510080 (China); Liang, Chang-Hong, E-mail: cjr.lchh@vip.163.com [Department of Radiology, Guangdong Academy of Medical Sciences, Guangdong General Hospital, 106 Zhongshan Er Road, Guangzhou 510080 (China); Zhao, Zhen-Jun, E-mail: junabc2006@hotmail.com [Department of Radiology, Guangdong Academy of Medical Sciences, Guangdong General Hospital, 106 Zhongshan Er Road, Guangzhou 510080 (China); Liu, Hui, E-mail: liuhuijiujiu@gmail.com [Department of Radiology, Guangdong Academy of Medical Sciences, Guangdong General Hospital, 106 Zhongshan Er Road, Guangzhou 510080 (China); Cui, Yan-Hai, E-mail: yanhai_cui@126.com [Department of Radiology, Guangdong Academy of Medical Sciences, Guangdong General Hospital, 106 Zhongshan Er Road, Guangzhou 510080 (China); Liu, Qi-Shun, E-mail: liuqishun@yeah.net [Department of Radiology, Guangdong Academy of Medical Sciences, Guangdong General Hospital, 106 Zhongshan Er Road, Guangzhou 510080 (China); Zhang, Jin-E., E-mail: zhjine@yahoo.com.cn [Department of Radiology, Guangdong Academy of Medical Sciences, Guangdong General Hospital, 106 Zhongshan Er Road, Guangzhou 510080 (China); Yang, Lin, E-mail: yanglin001517@163.com [Department of Radiology, Guangdong Academy of Medical Sciences, Guangdong General Hospital, 106 Zhongshan Er Road, Guangzhou 510080 (China); Ivanc, Thomas B., E-mail: Thomas.ivanc@philips.com [CT Clinical Science, Philips Healthcare, Highland Heights, OH (United States); Yanof, Jeffrey H., E-mail: Jeffrey.yanof@philips.com [CT Clinical Science, Philips Healthcare, Highland Heights, OH (United States)

2012-11-15

Purpose: To reduce radiation dose for retrospective ECG-triggered helical 256-slice CTCA by determining an optimal body size index to prospectively adjust tube current. Methods: 102 consecutive patients with suspected CAD underwent retrospective ECG-triggered CTCA using 256-slice CT scanner. Six body size indexes including BMI, nipple level (NL) bust, thoracic anteroposterior diameter at NL, chest circumference (CC) at NL, left main and right coronary artery (RCA) origin level were measured and their correlation with noise was evaluated using linear regression. An equation was developed to use this index to adjust tube current. Additional 102 consecutive patients were scanned with the index-based mA s adjustment. A t-test for independent samples was used to compare radiation dose levels with and without the index-based mA s selection method. Results: Linear regression indicated that CC RCA had the best correlation with noise (R{sup 2} = 0.603). Effective radiation dose was reduced from 16.6 {+-} 0.9 to 9.8 {+-} 2.7 mSv (p < 0.01), i.e. 40.9% lower dose with the CC RCA-adapted tube current method. The image quality scores indicated no significant difference with and without the size-based mA s selection method. Conclusion: An accessible measure of body size, such as CC RCA, can be used to adapt tube current for individualized radiation dose control.

Individualized radiation dose control in 256-slice CT coronary angiography (CTCA) in retrospective ECG-triggered helical scans: Using a measure of body size to adjust tube current selection

International Nuclear Information System (INIS)

Li, Jing-Lei; Huang, Mei-Ping; Liang, Chang-Hong; Zhao, Zhen-Jun; Liu, Hui; Cui, Yan-Hai; Liu, Qi-Shun; Zhang, Jin-E.; Yang, Lin; Ivanc, Thomas B.; Yanof, Jeffrey H.

2012-01-01

Purpose: To reduce radiation dose for retrospective ECG-triggered helical 256-slice CTCA by determining an optimal body size index to prospectively adjust tube current. Methods: 102 consecutive patients with suspected CAD underwent retrospective ECG-triggered CTCA using 256-slice CT scanner. Six body size indexes including BMI, nipple level (NL) bust, thoracic anteroposterior diameter at NL, chest circumference (CC) at NL, left main and right coronary artery (RCA) origin level were measured and their correlation with noise was evaluated using linear regression. An equation was developed to use this index to adjust tube current. Additional 102 consecutive patients were scanned with the index-based mA s adjustment. A t-test for independent samples was used to compare radiation dose levels with and without the index-based mA s selection method. Results: Linear regression indicated that CC RCA had the best correlation with noise (R 2 = 0.603). Effective radiation dose was reduced from 16.6 ± 0.9 to 9.8 ± 2.7 mSv (p < 0.01), i.e. 40.9% lower dose with the CC RCA-adapted tube current method. The image quality scores indicated no significant difference with and without the size-based mA s selection method. Conclusion: An accessible measure of body size, such as CC RCA, can be used to adapt tube current for individualized radiation dose control.

London-type congestion tax with revenue-recycling

OpenAIRE

Yukihiro Kidokoro

2005-01-01

Road pricing in London attracts a great deal of interest. A challenging aspect of the London scheme is that congestion tax revenue is used to upgrade public transit networks. Although Parry and Bento (2001) show that the total social surplus would increase if congestion tax revenues are used to cut labor taxes, political difficulties exist in implementing revenue-recycling between congestion taxes and labor taxes. Given such political difficulties, the London scheme seems to be very attractiv...

ENTRE RETRATOS E MEMÓRIAS: AS ILUSTRAÇÕES DE POTY EM DOM CASMURRO

Directory of Open Access Journals (Sweden)

Cilene Margarete Pereira

2010-01-01

Full Text Available En la edición de Dom Casmurro (colección "Clásicos Brasileños", los grabados del artista Poty revelan, en parte, adhesión al discurso del narrador, puntuando la imagen dudosa de Capitu. Sin embargo, en al menos dos ilustraciones, Poty señala otra perspectiva, capaz de descubrir la visión borrosa y amargado el narrador Bento Santiago en relación con la amiga de la infancia.

A Factorial Design Approach to Analyse the Effect of Coarse Recycled Concrete Aggregates on the Properties of Hot Mix Asphalt

Science.gov (United States)

Tanty, Kiranbala; Mukharjee, Bibhuti Bhusan; Das, Sudhanshu Shekhar

2018-02-01

The present study investigates the effect of replacement of coarse fraction of natural aggregates by recycled concrete aggregates on the properties of hot mix asphalt (HMA) using general factorial design approach. For this two factors i.e. recycled coarse aggregates percentage [RCA (%)] and bitumen content percentage [BC (%)] are considered. Tests have been carried out on the HMA type bituminous concrete, prepared with varying RCA (%) and BC (%). Analysis of variance has been performed on the experimental data to determine the effect of the chosen factors on various parameters such as stability, flow, air void, void mineral aggregate, void filled with bitumen and bulk density. The study depicts that RCA (%) and BC (%) have significant effect on the selected responses as p value is less than the chosen significance level. In addition to above, the outcomes of the statistical analysis indicate that interaction between factors have significant effects on void mineral aggregate and bulk density of bituminous concrete.

[Image fusion of gated-SPECT and CT angiography in coronary artery disease. Importance of anatomic-functional correlation].

Science.gov (United States)

Nazarena Pizzi, M; Aguadé Bruix, S; Cuéllar Calabria, H; Aliaga, V; Candell Riera, J

2010-01-01

A 77-year old patient was admitted for acute coronary syndrome without ST elevation. His risk was stratified using the myocardial perfusion gated SPECT, mild inferior ischemia being observed. Thus, medical therapy was optimized and the patient was discharged. He continued with exertional dyspnea so a coronary CT angiography was performed. It revealed severe lesions in the proximal RCA. SPECT-CT fusion images correlated the myocardial perfusion defect with a posterior descending artery from the RCA, in a co-dominant coronary area. Subsequently, cardiac catheterism was indicated for his treatment. The current use of image fusion studies is limited to patients in whom it is difficult to attribute a perfusion defect to a specific coronary artery. In our patient, the fusion images helped to distinguish between the RCA and the circumflex artery as the culprit artery of ischemia. Copyright © 2010 Elsevier España, S.L. y SEMNIM. All rights reserved.

A Factorial Design Approach to Analyse the Effect of Coarse Recycled Concrete Aggregates on the Properties of Hot Mix Asphalt

Science.gov (United States)

Tanty, Kiranbala; Mukharjee, Bibhuti Bhusan; Das, Sudhanshu Shekhar

2018-06-01

The present study investigates the effect of replacement of coarse fraction of natural aggregates by recycled concrete aggregates on the properties of hot mix asphalt (HMA) using general factorial design approach. For this two factors i.e. recycled coarse aggregates percentage [RCA (%)] and bitumen content percentage [BC (%)] are considered. Tests have been carried out on the HMA type bituminous concrete, prepared with varying RCA (%) and BC (%). Analysis of variance has been performed on the experimental data to determine the effect of the chosen factors on various parameters such as stability, flow, air void, void mineral aggregate, void filled with bitumen and bulk density. The study depicts that RCA (%) and BC (%) have significant effect on the selected responses as p value is less than the chosen significance level. In addition to above, the outcomes of the statistical analysis indicate that interaction between factors have significant effects on void mineral aggregate and bulk density of bituminous concrete.

Influence of a low calcium and phosphorus diet on the anabolic effect of human parathyroid hormone (1-38) in female rats

DEFF Research Database (Denmark)

Steiner, P.D.; Forrer, R.; Kneissel, Michaela

2001-01-01

Parathyroid hormone (PTH) or synthetic N-terminal PTH fragments administered intermittently have been established as anabolic agents in animal and human bones. In the present study, the influence of a low calcium diet on the anabolic effect of human PTH(1-38) [hPTH(1-38)] was investigated. Forty......-eight 10-week-old female Sprague-Dawley rats were randomly assigned to a diet with a low calcium content (LCa) or a diet with the recommended amount of calcium (RCa). After an adaptation period of 15 days, the rats were randomly assigned to hPTH(1-38) treatment (+LCa/+RCa) or vehicle only (-LCa....../-RCa) for an additional 14 days. Total bone mineral density (BMD) values of several bones were determined using quantitative computed tomography and from ratios of ash weight to volume. Biomechanical competence of the fourth lumbar vertebrae and of the right femora was assessed. An anabolic effect could be detected...

An Envelope Based Feedback Control System for Earthquake Early Warning: Reality Check Algorithm

Science.gov (United States)

Heaton, T. H.; Karakus, G.; Beck, J. L.

2016-12-01

Earthquake early warning systems are, in general, designed to be open loop control systems in such a way that the output, i.e., the warning messages, only depend on the input, i.e., recorded ground motions, up to the moment when the message is issued in real-time. We propose an algorithm, which is called Reality Check Algorithm (RCA), which would assess the accuracy of issued warning messages, and then feed the outcome of the assessment back into the system. Then, the system would modify its messages if necessary. That is, we are proposing to convert earthquake early warning systems into feedback control systems by integrating them with RCA. RCA works by continuously monitoring and comparing the observed ground motions' envelopes to the predicted envelopes of Virtual Seismologist (Cua 2005). Accuracy of magnitude and location (both spatial and temporal) estimations of the system are assessed separately by probabilistic classification models, which are trained by a Sparse Bayesian Learning technique called Automatic Relevance Determination prior.

Towards Better Understanding of Concrete Containing Recycled Concrete Aggregate

Directory of Open Access Journals (Sweden)

Hisham Qasrawi

2013-01-01

Full Text Available The effect of using recycled concrete aggregates (RCA on the basic properties of normal concrete is studied. First, recycled aggregate properties have been determined and compared to those of normal aggregates. Except for absorption, there was not a significant difference between the two. Later, recycled aggregates were introduced in concrete mixes. In these mixes, natural coarse aggregate was partly or totally replaced by recycled aggregates. Results show that the use of recycled aggregates has an adverse effect on the workability and air content of fresh concrete. Depending on the water/cement ratio and on the percent of the normal aggregate replaced by RCA, the concrete strength is reduced by 5% to 25%, while the tensile strength is reduced by 4% to 14%. All results are compared with previous research. As new in this research, the paper introduces a simple formula for the prediction of the modulus of elasticity of RCA concrete. Furthermore, the paper shows the variation of the air content of RAC.

Spanish Comics as Genre

Science.gov (United States)

Kiely, Kristin

2018-01-01

Since the beginning of literary time, genre has been an issue for critics and scholars. Comics and graphic novels have stepped into the fray in recent decades causing even more confusion. This is even more evident in Spain where the publishers are foolhardy men and women simply out to make money and who are too deeply embedded in their bourgeois…

O ofício do procurador geral das missões e a formação de redes sociais da Companhia de Jesus nas missões do Grão-Pará e Maranhão = The office of the attorney general of missions and the formation of networks of the Society of Jesus in missions of the Grão-Pará and Maranhão

Directory of Open Access Journals (Sweden)

Joaquim, Mariana Alliatti

2014-01-01

Full Text Available O presente artigo tem como foco de investigação a função exercida por um ex-missionário da Companhia de Jesus no Brasil, integrante do grupo de jesuítas expulsos da Vice-Província do Grão Pará e Maranhão encarcerado na prisão de São Julião da Barra, a partir da expulsão em 1759. O Padre Bento da Fonseca, neste momento, atuava em Lisboa como procurador geral das missões da Vice-Província do Grão-Pará e Maranhão, junto a autoridades civis e eclesiásticas. Desta forma, objetiva-se enquadrar o cargo do procurador geral das missões da Companhia de Jesus na formação e consolidação de redes socioeconômicas e de poder entre os jesuítas e os vários setores da sociedade lusitana. A partir do conceito de redes sociais, conforme definiram Barnes (1987, Castells (2011 e Elias (1994, far-se-á uma seleção e análise evolutiva da correspondência e de outros escritos de Bento da Fonseca, complementada com a análise sincrônica de outros textos produzidos

Brazilian sandy beaches: characteristics, ecosystem services, impacts, knowledge and priorities

Directory of Open Access Journals (Sweden)

Antonia Cecília Zacagnini Amaral

Full Text Available ABSTRACT Sandy beaches constitute a key ecosystem and provide socioeconomic goods and services, thereby playing an important role in the maintenance of human populations and in biodiversity conservation. Despite the ecological and social importance of these ecosytems, Brazilian sandy beaches are significantly impacted by human interference, chemical and organic pollution and tourism, as well as global climate change. These factors drive the need to better understand the environmental change and its consequences for biota. To promote the implementation of integrated studies to detect the effects of regional and global environmental change on beaches and on other benthic habitats of the Brazilian coast, Brazilian marine researchers have established The Coastal Benthic Habitats Monitoring Network (ReBentos. In order to provide input for sample planning by ReBentos, we have conducted an intensive review of the studies conducted on Brazilian beaches and summarized the current knowledge about this environment. In this paper, we present the results of this review and describe the physical, biological and socioeconomics features of Brazilian beaches. We have used these results, our personal experience and worldwide literature to identify research projects that should be prioritized in the assessment of regional and global change on Brazilian sandy beaches. We trust that this paper will provide insights for future studies and represent a significant step towards the conservation of Brazilian beaches and their biodiversity.

Mercúrio total em cabelos: uma contribuição para se avaliar o nível de exposição em Poconé, Mato Grosso, Brasil

Directory of Open Access Journals (Sweden)

Flávia Nogueira

Full Text Available Ocorrem na Bacia do Rio Bento Gomes (MT, às margens do Pantanal Mato-grossense, cerca de sessenta garimpos de ouro, onde o mercúrio é utilizado de forma intensiva nos processos de produção, através da formação de amálgamas que facilitam a aglutinação de partículas finas. A queima do amálgama nem sempre é feita em sistemas fechados de recuperação, havendo, portanto, perda de vapor para a atmosfera. Este estudo traz resultados de análises de mercúrio total nos cabelos de quatro grupos de voluntários que vivem em Poconé (MT, e faz uma caracterização geral do ambiente no que se refere à presença do metal na água e no sedimento do Rio Bento Gomes. Um equipamento de detecção por fluorescência foi usado para a determinação das concentrações, e os resultados indicam que os valores são mais baixos do que os de outras populações de áreas de garimpo no Brasil. Indicam também que a via ocupacional parece ser a mais eficiente rota potencial de contaminação da população por mercúrio.

Sensor Systems with Magnetic and Optomagnetic Readout of Rolling Circle Amplification Products

DEFF Research Database (Denmark)

Hansen, Mikkel Fougt; Donolato, Marco; Fock, Jeppe

2016-01-01

We are developing robust biosensors for homogeneous detection of rolling cirle amplification (RCA) products with magnetic and/or optomagnetic readouts based on surface-functionalized magnetic nanoparticles. Binding of RCA amplicons to nanoparticles modifies their ability to rotate in response...... to an applied oscillating magnetic field. As a result, magnetic or optical measurements of these changes in the rotational response of nanoparticles vs. frequency of the magnetic field can be used to quantitate the number of amplicons, and, hence, the concentration of target nucleic acid analytes. After...

Sensitive Blu-ray detection of clustered rolling circle products for molecular Diagnostics

DEFF Research Database (Denmark)

Ahlford, Annika; Donolato, Marco; Antunes, Paula Soares Martins

2014-01-01

In this paper we present a method for low cost and rapid sensing of nucleic acids (NA) for infectious diagnostics, where isothermal rolling circle amplification (RCA) products, specifically generated by the presence of the human pathogen Pseudomonas aeruginosa (PA), are bound to magnetic nanopart......In this paper we present a method for low cost and rapid sensing of nucleic acids (NA) for infectious diagnostics, where isothermal rolling circle amplification (RCA) products, specifically generated by the presence of the human pathogen Pseudomonas aeruginosa (PA), are bound to magnetic...

Recycled concrete aggregate (RCA) for infrastructure elements.

Science.gov (United States)

2014-07-01

With a growing demand for new construction and the need to replace infrastructure stretched beyond its service life, society faces the : problem of an ever-growing production of construction and demolition waste. The Federal Highway Administration (F...

Atmospheric circulation in regional climate models over Central Europe: links to surface air temperature and the influence of driving data

Energy Technology Data Exchange (ETDEWEB)

Plavcova, Eva [Institute of Atmospheric Physics, Academy of Sciences of the Czech Republic, Prague 4 (Czech Republic); Technical University, Department of Applied Mathematics, Liberec (Czech Republic); Charles University, Faculty of Mathematics and Physics, Prague (Czech Republic); Kysely, Jan [Institute of Atmospheric Physics, Academy of Sciences of the Czech Republic, Prague 4 (Czech Republic); Technical University, Department of Applied Mathematics, Liberec (Czech Republic)

2012-10-15

The study examines simulation of atmospheric circulation, represented by circulation indices (flow direction, strength and vorticity), and links between circulation and daily surface air temperatures in regional climate models (RCMs) over Central Europe. We explore control simulations of five high-resolution RCMs from the ENSEMBLES project driven by re-analysis (ERA-40) and the same global climate model (ECHAM5 GCM) plus of one RCM (RCA) driven by different GCMs. The aims are to (1) identify errors in RCM-simulated distributions of circulation indices in individual seasons, (2) identify errors in simulated temperatures under particular circulation indices, and (3) compare performance of individual RCMs with respect to the driving data. Although most of the RCMs qualitatively reflect observed distributions of the airflow indices, each produces distributions significantly different from the observations. General biases include overestimation of the frequency of strong flow days and of strong cyclonic vorticity. Some circulation biases obviously propagate from the driving data. ECHAM5 and all simulations driven by ECHAM5 underestimate frequency of easterly flow, mainly in summer. Except for HIRHAM, however, all RCMs driven by ECHAM5 improve on the driving GCM in simulating atmospheric circulation. The influence on circulation characteristics in the nested RCM differs between GCMs, as demonstrated in a set of RCA simulations with different driving data. The driving data control on circulation in RCA is particularly weak for the BCM GCM, in which case RCA substantially modifies (but does not improve) the circulation from the driving data in both winter and summer. Those RCMs with the most distorted atmospheric circulation are HIRHAM driven by ECHAM5 and RCA driven by BCM. Relatively strong relationships between circulation indices and surface air temperatures were found in the observed data for Central Europe. The links differ by season and are usually stronger for

Atmospheric circulation in regional climate models over Central Europe: links to surface air temperature and the influence of driving data

International Nuclear Information System (INIS)

Plavcova, Eva; Kysely, Jan

2012-01-01

The study examines simulation of atmospheric circulation, represented by circulation indices (flow direction, strength and vorticity), and links between circulation and daily surface air temperatures in regional climate models (RCMs) over Central Europe. We explore control simulations of five high-resolution RCMs from the ENSEMBLES project driven by re-analysis (ERA-40) and the same global climate model (ECHAM5 GCM) plus of one RCM (RCA) driven by different GCMs. The aims are to (1) identify errors in RCM-simulated distributions of circulation indices in individual seasons, (2) identify errors in simulated temperatures under particular circulation indices, and (3) compare performance of individual RCMs with respect to the driving data. Although most of the RCMs qualitatively reflect observed distributions of the airflow indices, each produces distributions significantly different from the observations. General biases include overestimation of the frequency of strong flow days and of strong cyclonic vorticity. Some circulation biases obviously propagate from the driving data. ECHAM5 and all simulations driven by ECHAM5 underestimate frequency of easterly flow, mainly in summer. Except for HIRHAM, however, all RCMs driven by ECHAM5 improve on the driving GCM in simulating atmospheric circulation. The influence on circulation characteristics in the nested RCM differs between GCMs, as demonstrated in a set of RCA simulations with different driving data. The driving data control on circulation in RCA is particularly weak for the BCM GCM, in which case RCA substantially modifies (but does not improve) the circulation from the driving data in both winter and summer. Those RCMs with the most distorted atmospheric circulation are HIRHAM driven by ECHAM5 and RCA driven by BCM. Relatively strong relationships between circulation indices and surface air temperatures were found in the observed data for Central Europe. The links differ by season and are usually stronger for

The cause and influence of self-cementing properties of fine recycled concrete aggregates on the properties of unbound sub-base

International Nuclear Information System (INIS)

Poon, C.-S.; Qiao, X.C.; Chan, Dixon

2006-01-01

The use of coarse recycled concrete aggregates (CRCA) in conjunction with fine recycled concrete aggregates (FRCA) as sub-base materials has been widely studied. Although research results indicate that it is feasible to employ both CRCA and FRCA as granular sub-base, the influence of the unhydrated cement in the adhered mortar of the RCA on the properties of the sub-base materials has not been thoroughly studied. Generally, it is known that the strength of the sub-base materials prepared with RCA increases over time. However, this mechanism, known as the self-cementing properties, is not well understood and is believed to be governed by the properties of the fine portion of the RCA (<5 mm). This paper presents an investigation on the cause of the self-cementing properties by measuring X-ray diffraction patterns, pH values, compressive strength and permeability of various size fractions of the FRCA obtained from a commercially operated construction and demolition waste recycling plant. Their influence on the overall sub-base materials was determined. The results indicate that the size fractions of <0.15 and 0.3-0.6 mm (active fractions) were most likely to be the principal cause of the self-cementing properties of the FRCA. However, the effects on the properties of the overall RCA sub-base materials were minimal if the total quantity of the active fractions was limited to a threshold by weight of the total fine aggregate

Morphogenes bolA and mreB mediate the photoregulation of cellular morphology during complementary chromatic acclimation in Fremyella diplosiphon.

Science.gov (United States)

Singh, Shailendra P; Montgomery, Beronda L

2014-07-01

Photoregulation of pigmentation during complementary chromatic acclimation (CCA) is well studied in Fremyella diplosiphon; however, mechanistic insights into the CCA-associated morphological changes are still emerging. F. diplosiphon cells are rectangular under green light (GL), whereas cells are smaller and spherical under red light (RL). Here, we investigate the role of morphogenes bolA and mreB during CCA using gene expression and gene function analyses. The F. diplosiphon bolA gene is essential as its complete removal from the genome was unsuccessful. Depletion of bolA resulted in slow growth, morphological defects and the accumulation of high levels of reactive oxygen species in a partially segregated ΔbolA strain. Higher expression of bolA was observed under RL and was correlated with lower expression of mreB and mreC genes in wild type. In a ΔrcaE strain that lacks the red-/green-responsive RcaE photoreceptor, the expression of bolA and mre genes was altered under both RL and GL. Observed gene expression relationships suggest that mreB and mreC expression is controlled by RcaE-dependent photoregulation of bolA expression. Expression of F. diplosiphon bolA and mreB homologues in Escherichia coli demonstrated functional conservation of the encoded proteins. Together, these studies establish roles for bolA and mreB in RcaE-dependent regulation of cellular morphology. © 2014 John Wiley & Sons Ltd.

Impact of climate change on surface ozone and deposition of sulphur and nitrogen in Europe

Energy Technology Data Exchange (ETDEWEB)

Langner, J.; Bergstroem, R.; Foltescu, V. [Swedish Meteorological and Hydrological Institute, Norrkoeping (Sweden)

2005-02-01

The potential impact of regional climate change on the distribution and deposition of air pollutants in Europe has been studied using a regional chemistry/transport/deposition model, MATCH. MATCH was set up using meteorological output from two 10-year climate change experiments made with the Rossby Centre regional Atmospheric climate model version 1 (RCA1). RCA1 was forced by boundary conditions from two different global climate models using the IPCC IS92a (business as usual) emission scenario. The global mean warming in both the GCMs was 2.6 K and was reached in the period 2050-2070. Simulations with MATCH indicate substantial potential impact of regional climate change on both deposition of oxidised nitrogen and concentrations of surface ozone. The simulations show a strong increase in surface ozone expressed as AOT40 and mean of daily maximum over southern and central Europe and a decrease in northern Europe. The simulated changes in April-September AOT40 are significant in relation to inter-annual variability over extended areas. Changes in deposition of oxidised nitrogen are much smaller and also less coherent due to the strong inter-annual variability in precipitation in the RCA1 simulations and differences in the regional climate change simulated with RCA1 in the two regional scenarios. Changes in simulated annual deposition are significant in relation to inter-annual variability only over small areas. This indicates that longer simulation periods are necessary to establish changes in deposition. (author)

Impact of climate change on surface ozone and deposition of sulphur and nitrogen in Europe

Science.gov (United States)

Langner, Joakim; Bergström, Robert; Foltescu, Valentin

The potential impact of regional climate change on the distribution and deposition of air pollutants in Europe has been studied using a regional chemistry/transport/deposition model, MATCH. MATCH was set up using meteorological output from two 10-year climate change experiments made with the Rossby Centre regional Atmospheric climate model version 1 (RCA1). RCA1 was forced by boundary conditions from two different global climate models using the IPCC IS92a (business as usual) emission scenario. The global mean warming in both the GCMs was 2.6 K and was reached in the period 2050-2070. Simulations with MATCH indicate substantial potential impact of regional climate change on both deposition of oxidised nitrogen and concentrations of surface ozone. The simulations show a strong increase in surface ozone expressed as AOT40 and mean of daily maximum over southern and central Europe and a decrease in northern Europe. The simulated changes in April-September AOT40 are significant in relation to inter-annual variability over extended areas. Changes in deposition of oxidised nitrogen are much smaller and also less coherent due to the strong inter-annual variability in precipitation in the RCA1 simulations and differences in the regional climate change simulated with RCA1 in the two regional scenarios. Changes in simulated annual deposition are significant in relation to inter-annual variability only over small areas. This indicates that longer simulation periods are necessary to establish changes in deposition.

Toxicity and environmental and economic performance of fly ash and recycled concrete aggregates use in concrete: A review

Directory of Open Access Journals (Sweden)

Rawaz Kurda

2018-04-01

Full Text Available This paper presents an overview of previous studies on the environmental impact (EI and toxicity of producing recycled concrete aggregates (RCA, fly ash (FA, cement, superplasticizer, and water as raw materials, and also on the effect of replacing cement and natural aggregates (NA with FA and RCA, respectively, on the mentioned aspects. EI and toxicity were analysed simultaneously because considering concrete with alternative materials as sustainable depends on whether their risk assessment is high. Therefore, this study mainly focuses on the cradle-to-gate EI of one cubic meter of concrete, namely abiotic depletion potential (ADP, global warming potential (GWP, ozone depletion potential (ODP, photochemical ozone creation (POCP, acidification potential (AP, eutrophication potential (EP, non-renewable energy (PE-NRe and renewable energy (PE-Re. In terms of toxicity, leachability (chemical and ecotoxicological characterization was considered. The results also include the economic performance of these materials, and show that the incorporation of FA in concrete significantly decreases the EI and cost of concrete. Thus, the simultaneous incorporation of FA and RCA decrease the EI, cost, use of landfill space and natural resources extraction. Nonetheless, the leaching metals of FA decrease when they are incorporated in concrete. Relative to FA, the incorporation of RCA does not significantly affect the EI and cost of concrete, but it significantly reduces the use of landfill space and the need of virgin materials. Keywords: Materials science, Environmental science, Industry, Economics, Safety engineering

Single-molecule diffusometry reveals the nucleotide-dependent oligomerization pathways of Nicotiana tabacum Rubisco activase

Science.gov (United States)

Wang, Quan; Serban, Andrew J.; Wachter, Rebekka M.; Moerner, W. E.

2018-03-01

Oligomerization plays an important role in the function of many proteins, but a quantitative picture of the oligomer distribution has been difficult to obtain using existing techniques. Here we describe a method that combines sub-stoichiometric labeling and recently developed single-molecule diffusometry to measure the size distribution of oligomers under equilibrium conditions in solution, one molecule at a time. We use this technique to characterize the oligomerization behavior of Nicotiana tabacum (Nt) Rubisco activase (Nt-Rca), a chaperone-like AAA-plus ATPase essential in regulating carbon fixation during photosynthesis. We directly observed monomers, dimers, and a tetramer/hexamer mixture and extracted their fractional abundance as a function of protein concentration. We show that the oligomerization pathway of Nt-Rca is nucleotide dependent: ATPγS binding strongly promotes tetramer/hexamer formation from dimers and results in a preferred tetramer/hexamer population for concentrations in the 1-10 μM range. Furthermore, we directly observed dynamic assembly and disassembly processes of single complexes in real time and from there estimated the rate of subunit exchange to be ˜0.1 s-1 with ATPγS. On the other hand, ADP binding destabilizes Rca complexes by enhancing the rate of subunit exchange by >2 fold. These observations provide a quantitative starting point to elucidate the structure-function relations of Nt-Rca complexes. We envision the method to fill a critical gap in defining and quantifying protein assembly pathways in the small-oligomer regime.

The use of 2N3055 transistor as photosensory in solarymeter

International Nuclear Information System (INIS)

Bintoro; Sastroamidjojo, M.S.A.

1981-01-01

The characteristics of 2N3055 type transistor used for solarymeters sensor. It can be seen that transistor sensor has more response time. The response to against arrival solar intensity is linear. It can be used for solarymeter sensor after calibrated with pyranometer reference, but not so sensitive for 500 nanometer wavelength. It can be concluded that 2N3055 transistor made by Motrola than the made by R.C.A. because the 2N3055 transistor is more wide and more accurate than the R.C.A. transistor. (author tr.)

Dew inspired breathing-based detection of genetic point mutation visualized by naked eye

Science.gov (United States)

Xie, Liping; Wang, Tongzhou; Huang, Tianqi; Hou, Wei; Huang, Guoliang; Du, Yanan

2014-09-01

A novel label-free method based on breathing-induced vapor condensation was developed for detection of genetic point mutation. The dew-inspired detection was realized by integration of target-induced DNA ligation with rolling circle amplification (RCA). The vapor condensation induced by breathing transduced the RCA-amplified variances in DNA contents into visible contrast. The image could be recorded by a cell phone for further or even remote analysis. This green assay offers a naked-eye-reading method potentially applied for point-of-care liver cancer diagnosis in resource-limited regions.

Dual-artery stenting of a type III single coronary artery from right aortic sinus

Directory of Open Access Journals (Sweden)

Shivanad Patil

2015-12-01

Full Text Available A single coronary artery presenting with stenosis in two of the three vessels arising from a common ostium is a rare anomaly Lipton et al. proposed a classification, which was modified by Yamanaka and Hobbs. In our case, a single coronary artery was giving rise to the LAD, left circumflex (LCx, and the right coronary artery (RCA. There was 80% stenosis in the ostium of the LCx. The RCA in the mid and distal segment had stenosis of 80% and 70%, respectively. We were able to successfully stent the three stenotic segments.

Impact Resistance of Recycled Aggregate Concrete with Single and Hybrid Fibers

Directory of Open Access Journals (Sweden)

Ismail Sallehan

2016-01-01

Full Text Available This paper presents a recycled aggregate concrete (RAC mix that has been modified by adding treated recycled concrete aggregate (RCA and various types of fiber-reinforced systems. The effectiveness of these modifications in terms of energy absorption and impact resistance was evaluated and compared with that of the corresponding regular concrete, as well as with unmodified RAC specimens. Results clearly indicate that although modification of the RAC mix with treated RCA significantly enhances the impact resistance of RAC, further diversification with additional fiber, particularly those in hybrid form, can optimize the results.

Root Cause Analysis Following an Event at a Nuclear Installation: Reference Manual

International Nuclear Information System (INIS)

2015-01-01

Following an event at a nuclear installation, it is important to determine accurately its root causes so that effective corrective actions can be implemented. As stated in IAEA Safety Standards Series No. SF-1, Fundamental Safety Principles: “Processes must be put in place for the feedback and analysis of operating experience”. If this process is completed effectively, the probability of a similar event occurring is significantly reduced. Guidance on how to establish and implement such a process is given in IAEA Safety Standards Series No. NS-G-2.11, A System for the Feedback of Experience from Events in Nuclear Installations. To cater for the diverse nature of operating experience events, several different root cause analysis (RCA) methodologies and techniques have been developed for effective investigation and analysis. An event here is understood as any unanticipated sequence of occurrences that results in, or potentially results in, consequences to plant operation and safety. RCA is not a topic uniquely relevant to event investigators: knowledge of the concepts enhances the learning characteristics of the whole organization. This knowledge also makes a positive contribution to nuclear safety and helps to foster a culture of preventing event occurrence. This publication allows organizations to deepen their knowledge of these methodologies and techniques and also provides new organizations with a broad overview of the RCA process. It is the outcome of a coordinated effort involving the participation of experts from nuclear organizations, the energy industry and research centres in several Member States. This publication also complements IAEA Services Series No. 10, PROSPER Guidelines: Guidelines for Peer Review and for Plant Self- Assessment of Operational Experience Feedback Process, and is intended to form part of a suite of publications developing the principles set forth in these guidelines. In addition to the information and description of RCA

DAYA SAING DAN PERMINTAAN EKSPOR PRODUK BIOFARMAKA INDONESIA DI NEGARA TUJUAN UTAMA PERIODE 2003-2012

Directory of Open Access Journals (Sweden)

Irgandhini Agra Kanaya

2015-03-01

Full Text Available The world demand of herbal medicine is mounting. The more intensive effort is surely required in order to meet the supply of raw materials of medicinal products needed. The purposes of this research are to observe the competitiveness between countries in the world toward the provision of export products and also to analyze the affecting factors of export demand of medicinal products to the destination countries. The methods of analysis used in this research are Revealed Comparative Advantage (RCA, Export Product Dynamics (EPD, and Gravity Model. The analyzed period was an average of 2003 until 2012. The results of this research conclude that Indonesia has a good competitiveness in the commodity of turmeric and gaharu wood compared to the competitor countries based on the analysis of RCA and EPD, with the position of competitiveness of "Lost Oppportunity". Based on Gravity Model, the factors affecting the demand of medicinal products are Real GDP, Real Exchange Rate, Population, and Economic Distance. All those variables significantly influence the dependent variable and are consistent with the hypothesis.Keywords: export, EPD, gavity model, medical product, RCAABSTRAKPermintaan obat herbal dunia semakin meningkat, tentunya diperlukan usaha yang lebih intensif agar pasokan bahan baku produk biofarmaka dapat terpenuhi. Penelitian ini bertujuan melihat bagaimana daya saing yang terjadi antardua negara di dunia terhadap penyediaan produk ekspor serta menganalisis faktor yang memengaruhi permintaan ekspor produk biofarmaka dunia terhadap negara tujuan utama. Metode analisis yang digunakan dalam penenelitian ini adalah Revealed Comparative Advantage (RCA, Export Product Dynamics (EPD dan Gravity Model. Periode waktu yang diteliti adalah rata-rata tahun 2003 hingga 2012. Hasil penelitian menyimpulkan bahwa Indonesia memiliki daya saing yang baik terhadap komoditi kunyit dan kayu gaharu apabila dibandingkan dengan negara pesaing berdasarkan analisis RCA

POSISI DAYA SAING DAN FAKTOR-FAKTOR YANG MEMENGARUHI EKSPOR BUAH-BUAHAN INDONESIA

Directory of Open Access Journals (Sweden)

Amalia Pradipta

2015-02-01

Full Text Available The success of competitiveness of Indonesian fruits export in the destination countries is determined by comparative and competitive advantage and other factors. Revealed Comparative Advantage (RCA and Export Product Dynamic (EPD are used in this research to analyze the position of competitiveness of Indonesian fruits export. This research also uses panel gravity model to analyze the factors which affect the export volume of Indonesia fruits (mango, mangosteen, rambutan, banana, and melon. The results from EPD and RCA method show that fruits which have the highest comparative and competitive advantage in destination countries and the world are mangoesteen, mango, and guava. Indonesian fruit which lost its opportunity to compete in the destination countries is strawberry. The results of this research shows that the factors which influence the export of Indonesian fruits to the destination countries are export price, population, economic distance, real GDP and GDP per capita, real exchange rate, Indonesian consumer price index, and dummy variable of crisis which happened in Europe.Keywords: competitiveness, EPD, gravity model, RCAABSTRAKKeberhasilan daya saing ekspor buah Indonesia di negara tujuan ditentukan oleh keunggulan komparatif dan kompetitif serta faktor lainnya. Revealed Comparative Advantage (RCA dan Export Product Dynamic (EPD digunakan untuk menganalisis posisi daya saing ekspor buah-buahan Indonesia. Pada penelitian ini digunakan analisis data panel gravity model untuk menganalisis faktor-faktor yang memengaruhi aliran volume ekspor buah-buahan Indonesia (mangga, manggis, rambutan, pisang, dan melon. Pada metode Export Product Dynamic (EPD dan Revealed Comparative Advantage (RCA menunjukkan bahwa buah yang memiliki keunggulan komparatif dan kompetitif tertinggi di negara tujuan dan dunia adalah buah manggis, mangga, dan jambu. Ekspor buah Indonesia yang kehilangan kesempatan dalam bersaing di negara tujuan adalah stroberi. Hasil

Root Cause Analysis Following an Event at a Nuclear Installation: Reference Manual. Companion CD

International Nuclear Information System (INIS)

2015-01-01

Following an event at a nuclear installation, it is important to determine accurately its root causes so that effective corrective actions can be implemented. As stated in IAEA Safety Standards Series No. SF-1, Fundamental Safety Principles: “Processes must be put in place for the feedback and analysis of operating experience”. If this process is completed effectively, the probability of a similar event occurring is significantly reduced. Guidance on how to establish and implement such a process is given in IAEA Safety Standards Series No. NS-G-2.11, A System for the Feedback of Experience from Events in Nuclear Installations. To cater for the diverse nature of operating experience events, several different root cause analysis (RCA) methodologies and techniques have been developed for effective investigation and analysis. An event here is understood as any unanticipated sequence of occurrences that results in, or potentially results in, consequences to plant operation and safety. RCA is not a topic uniquely relevant to event investigators: knowledge of the concepts enhances the learning characteristics of the whole organization. This knowledge also makes a positive contribution to nuclear safety and helps to foster a culture of preventing event occurrence. This publication allows organizations to deepen their knowledge of these methodologies and techniques and also provides new organizations with a broad overview of the RCA process. It is the outcome of a coordinated effort involving the participation of experts from nuclear organizations, the energy industry and research centres in several Member States. This publication also complements IAEA Services Series No. 10, PROSPER Guidelines: Guidelines for Peer Review and for Plant Self- Assessment of Operational Experience Feedback Process, and is intended to form part of a suite of publications developing the principles set forth in these guidelines. In addition to the information and description of RCA

Rolling cycle amplification based single-color quantum dots–ruthenium complex assembling dyads for homogeneous and highly selective detection of DNA

Energy Technology Data Exchange (ETDEWEB)

Su, Chen; Liu, Yufei; Ye, Tai; Xiang, Xia; Ji, Xinghu; He, Zhike, E-mail: zhkhe@whu.edu.cn

2015-01-01

Graphical abstract: A universal, label-free, homogeneous, highly sensitive, and selective fluorescent biosensor for DNA detection is developed by using rolling-circle amplification (RCA) based single-color quantum dots–ruthenium complex (QDs–Ru) assembling dyads. - Highlights: • The single-color QDs–Ru assembling dyads were applied in homogeneous DNA assay. • This biosensor exhibited high selectivity against base mismatched sequences. • This biosensor could be severed as universal platform for the detection of ssDNA. • This sensor could be used to detect the target in human serum samples. • This DNA sensor had a good selectivity under the interference of other dsDNA. - Abstract: In this work, a new, label-free, homogeneous, highly sensitive, and selective fluorescent biosensor for DNA detection is developed by using rolling-circle amplification (RCA) based single-color quantum dots–ruthenium complex (QDs–Ru) assembling dyads. This strategy includes three steps: (1) the target DNA initiates RCA reaction and generates linear RCA products; (2) the complementary DNA hybridizes with the RCA products to form long double-strand DNA (dsDNA); (3) [Ru(phen){sub 2}(dppx)]{sup 2+} (dppx = 7,8-dimethyldipyrido [3,2-a:2′,3′-c] phenanthroline) intercalates into the long dsDNA with strong fluorescence emission. Due to its strong binding propensity with the long dsDNA, [Ru(phen){sub 2}(dppx)]{sup 2+} is removed from the surface of the QDs, resulting in restoring the fluorescence of the QDs, which has been quenched by [Ru(phen){sub 2}(dppx)]{sup 2+} through a photoinduced electron transfer process and is overlaid with the fluorescence of dsDNA bonded Ru(II) polypyridyl complex (Ru-dsDNA). Thus, high fluorescence intensity is observed, and is related to the concentration of target. This sensor exhibits not only high sensitivity for hepatitis B virus (HBV) ssDNA with a low detection limit (0.5 pM), but also excellent selectivity in the complex matrix. Moreover

Teresa y Luis, Luis y Teresa. Dos santos en tiempos recios

Directory of Open Access Journals (Sweden)

Emilio Callado Estela

2016-06-01

Full Text Available El presente artículo analiza la relación entre dos grandes santos españoles de la Contrarreforma Católica, Teresa de Jesús y el dominico fray Luis Bertrán. The present article analyses the relation between two big Spanish saints of the Catholic Counterreformation, Teresa de Jesus and the Dominican monk Luis Bertrán.

FOCUS THE CONSUMER MARKET A dream or reality for multinational companies

Institute of Scientific and Technical Information of China (English)

MICHAELO＇NEILL

2004-01-01

As the Chinese economy maintains its near double digit growth, opportunities for foreign investors continue to emerge. But away from the staggering statistics, how realistic is the China dream for multinational companies (MNCs)? The messages are mixed. On the one hand are those who continue to hail the Chinese consumer revolution, pointing to market size as reason enough for entering the fray. O'n the other

Antônio, Bento e Domingos: paternidade na elite farroupilha (1835-1845 = Antônio, Bento and Domingos: fatherhood among the farroupilha’s elite (1835-1845

Directory of Open Access Journals (Sweden)

Barbosa, Carla Adriana da Silva

2017-01-01

Full Text Available Num contexto marcado pela guerra e preponderância das imagens masculinas, a figura paterna representava a segurança corporal e simbólica das famílias da elite farroupilha. Neste artigo, analiso as manifestações de paternidade nas correspondências pertencentes a este grupo, como as escolhas para a educação e o legado a ser herdado por seus filhos

Compilation of anatomical, physiological and metabolic characteristics for a Reference Asian Man. Volume 1: data summary and conclusions. Results of a co-ordinated research programme 1988-1993

International Nuclear Information System (INIS)

1998-02-01

The Co-ordinated Research Programme (CRP) on Compilation of Anatomical, Physiological and Metabolic Characteristics for a Reference Asian Man has been conducted as a programme of the IAEA Regional Co-operative Agreement (RCA) for Asia and the Pacific. The CRP was conducted to provide data for radiation protection purposes that is relevant to the biokinetic and dosimetric characteristics of the ethnic populations in the Asian region. The radiological protection decisions that had to be made in the RCA member States following the Chernobyl accident were a significant motivation for establishing the CRP. Eleven RCA Member States participated in the CRP. Research co-ordination meetings (RCMs) for the CRP were held in Mito City, Japan, 17-21 October 1988 and Bhabha Atomic Research Centre, India, 8-12 April 1991. The concluding meeting was held in Tianjin, China, 25-29 October 1993. This publication is divided into two volumes: Volume 1 contains a summary of the data and conclusions from the project and Volume 2 the reports from participating countries

The feasibility of transradial laser atherectomy for chronic total occlusion using the 5 Fr sheath system

Directory of Open Access Journals (Sweden)

Khaled Sherif

2016-05-01

Full Text Available Objective. We present a case of chronic total occlusion (CTO approached with LASER endovascular intervention by radial artery approach using a 5 French sheath. Case report. A 57-year-old man presented to our hospital having had retrosternal chest pain for two days. Physical examination was normal at the time of presentation. The laboratory tests were within normal limits, including cardiac enzymes except the lipid panel which showed hypertriglyceridemia. The patient underwent a myocardial perfusion scintigraphy stress test that revealed inferior wall ischemia, with normal left ventricular ejection fraction. A 5-French vascular sheath was placed in the right radial artery. Selective coronary artery angiography was performed, which showed right coronary artery (RCA CTO. A 5-French JR4 guide catheter successfully engaged the RCA and Laser angioplasty was performed across the CTO into the RCA. A marked improvement of flow was evident thereafter. Conclusion. To best of our knowledge this is the first case report showing the feasibility of laser atherectomy using the 5 French sheath system in a coronary arterial CTO.

The feasibility of transradial laser atherectomy for chronic total occlusion using the 5 Fr sheath system.

Science.gov (United States)

Sherif, Khaled; Yaqub, Yasir; Suarez, Jose A

2016-05-01

We present a case of chronic total occlusion (CTO) approached with LASER endovascular intervention by radial artery approach using a 5 French sheath. A 57-year-old man presented to our hospital having had retrosternal chest pain for two days. Physical examination was normal at the time of presentation. The laboratory tests were within normal limits, including cardiac enzymes except the lipid panel which showed hypertriglyceridemia. The patient underwent a myocardial perfusion scintigraphy stress test that revealed inferior wall ischemia, with normal left ventricular ejection fraction. A 5-French vascular sheath was placed in the right radial artery. Selective coronary artery angiography was performed, which showed right coronary artery (RCA) CTO. A 5-French JR4 guide catheter successfully engaged the RCA and Laser angioplasty was performed across the CTO into the RCA. A marked improvement of flow was evident thereafter. To best of our knowledge this is the first case report showing the feasibility of laser atherectomy using the 5 French sheath system in a coronary arterial CTO. Copyright © 2016 by Academy of Sciences and Arts of Bosnia and Herzegovina.

Performance analysis of a complete adiabatic logic system driven by the proposed power clock generator

International Nuclear Information System (INIS)

Kanungo, Jitendra; Dasgupta, S.

2014-01-01

We analyze the energy performance of a complete adiabatic circuit/system including the Power Clock Generator (PCG) at the 90 nm CMOS technology node. The energy performance in terms of the conversion efficiency of the PCG is extensively carried out under the variations of supply voltage, process corner and the driver transistor's width. We propose an energy-efficient singe cycle control circuit based on the two-stage comparator for the synchronous charge recovery sinusoidal power clock generator (PCG). The proposed PCG is used to drive the 4-bit adiabatic Ripple Carry Adder (RCA) and their simulation results are compared with the adiabatic RCA driven by the reported PCG. We have also simulated the logically equivalent static CMOS RCA circuit to compare the energy saving of adiabatic and non-adiabatic logic circuits. In the clock frequency range from 25 MHz to 1GHz, the proposed PCG gives a maximum conversion efficiency of 56.48%. This research work shows how the design of an efficient PCG increases the energy saving of adiabatic logic. (semiconductor integrated circuits)

Competitiveness of Indonesian Shrimp Compare with Thailand Shrimp in Export Market

Directory of Open Access Journals (Sweden)

Lina Asmara Wati

2013-09-01

Full Text Available With the water area accounts for 81 percent of the total area, fishery is a major business in Indonesia. As one of the world's largest shrimp exporting countries, Indonesia also relies on the revenues of shrimp exports in the international markets. This research compared the competitiveness of shrimp export from Indonesia and Thailand to Japan and US. The indicator adopted in this research was the RCA index. In this research collected secondary data from 1989 to 2010 for analysis. Results showed RCA values of Indonesia were higher than 1, which indicates advantaged competitiveness of Indonesia shrimp exports in the liberalized markets. Nevertheless, compared with Thailand, Indonesia remained relatively disadvantaged. To reinforce the Indonesian shrimp export, necessary infrastructure, such as networks shipment or delivery, packaging and transportation, must be improved. Further researches to determine the factors affecting competitiveness of export shrimp in liberalized market, make and analyze for the policy strategy formulation of Indonesia shrimp export in liberalized market are also advised.Keywords: Competitiveness; Indonesian Shrimp Export; RCA.

Managing practical issues with percutaneous treatment of spontaneous coronary artery dissection in the cardiac catheterization laboratory: An interesting case report

Directory of Open Access Journals (Sweden)

T G Varghese

2017-01-01

Full Text Available Spontaneous coronary artery dissection (SCAD is a rare condition and uncommon cause of acute coronary syndrome which is associated with high acute phase mortality with an estimated prevalence of approximately 0.7%. SCAD is known to occur more commonly in young women during pregnancy or postpartum period, and in most cases, it involves a single coronary artery. It has also been reported in patients with atherosclerosis. SCAD is generally treated by percutaneous intervention and stenting. While stenting a segment of the right coronary artery (RCA with dissection, opening the balloon in the false lumen or placing a stent in the false plane can lead to abrupt closure of the RCA leading to on table catastrophe, thereby confirming that we are in the true lumen is of pivotal importance. Simple maneuvers to prevent this error can be lifesaving. In this article, we have presented a few practical measures to deal with this dilemma in the background of a patient who was found to have spontaneous spiral dissection of the RCA while being evaluated for angina.

Effect of regional citrate anticoagulation on critical patients with continuous renal replacement therapy

Directory of Open Access Journals (Sweden)

Li-Li You

2016-12-01

Full Text Available Objective: To investigate the efficacy and safety of regional citrate anticoagulation (RCA in continuous renal replacement therapy (CRRT for critical patients. Methods: A total of 83 critical patients need CRRT in the intensive care units of our hospital from July 2012 to June 2016 were recruited in the study, and the patients were divided into two groups randomly, the patients in observation group received the RCA treatment, and the patients in control group received traditional low molecular heparin anticoagulation. The difference of safety indicators, biochemical indicators, extracorporeal circulation blood coagulation condition and complications in patients were determined between two groups. Results: Compared with control group, the patients in observation group had an elevated level of iCa2+, the level of chloride ion reduced, the use time of filter increased, the bleeding cases reduced, the concentrations of urea nitrogen, creatinine TNF-α , IL-1β, IL-8 and NO were all significantly downregulated, the data have a significant difference (P < 0.05. Conclusions: RCA is a safe and effective method for CRRT in patients with a high risk of bleeding.

Compilation of anatomical, physiological and metabolic characteristics for a Reference Asian Man. Volume 1: data summary and conclusions. Results of a co-ordinated research programme 1988-1993

Energy Technology Data Exchange (ETDEWEB)

NONE

1998-02-01

The Co-ordinated Research Programme (CRP) on Compilation of Anatomical, Physiological and Metabolic Characteristics for a Reference Asian Man has been conducted as a programme of the IAEA Regional Co-operative Agreement (RCA) for Asia and the Pacific. The CRP was conducted to provide data for radiation protection purposes that is relevant to the biokinetic and dosimetric characteristics of the ethnic populations in the Asian region. The radiological protection decisions that had to be made in the RCA member States following the Chernobyl accident were a significant motivation for establishing the CRP. Eleven RCA Member States participated in the CRP. Research co-ordination meetings (RCMs) for the CRP were held in Mito City, Japan, 17-21 October 1988 and Bhabha Atomic Research Centre, India, 8-12 April 1991. The concluding meeting was held in Tianjin, China, 25-29 October 1993. This publication is divided into two volumes: Volume 1 contains a summary of the data and conclusions from the project and Volume 2 the reports from participating countries. Refs, figs, tabs.

La Biblioteca del Monasterio de Fitero a fines del Renacimiento e inicio del Barroco

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Ostolaza Elizondo, Maria Isabel

2013-06-01

Full Text Available The article describes the time of the creation of library of the Cistercian monastery of Fitero (Navarre. Over the years it became one of the most important in the kingdom, until its decline trougth secularisations and confiscations of property suffered by the convent in the 19th century. The data on its initial phase come from the books of the abbots Fray Marcos de Villalva and Fray Ignacio Fermín de Ibero, both originally from Castile, who were appointed abbots vy virtue of the righ to royal patronage exercised by King Philip II. Although most of the books belong, as could be expected to an ecclesiastical library, a surprising case inthat of Abbot Ibero for the wide range of subjets he covers and the high quality of the editions, often accompanied by engravings and musical notes. Through these books, which are either identified through the exlibris or references ot notarial list, one can perceive the important ecclesiastical issues of the day: the reform of the monasteries and the practice of Orthodox Catholicism, and also secular issues that came to the knowledge of the monastery related to the two great powers of the Catholic world, the monarchy and the papacy.El artículo recoge los momentos de la creación de la biblioteca del monasterio cisterciense de Fitero (Navarra, que sería con el tiempo una de las más importantes de ese reino, hasta su mengua por causa de las distintas exclaustraciones y desamortizaciones que sufrió el convento en el s. XIX. Los datos de estos primeros tiempos corresponden a las librerías de fray Marcos de Villalva y fray Ignacio Fermín de Ibero, ambos procedentes de Castilla y nombrados abades fiterenses en virtud del derecho de patronato real ejercido por Felipe II. Aunque la mayoría de los libros corresponden a lo que se entendería como lógico en una biblioteca eclesiástica, sorprende en el caso de la del abad Ibero la amplitud de la temática y la calidad de las ediciones, en muchos casos con grabados

Right colic artery anatomy: a systematic review of cadaveric studies.

Science.gov (United States)

Haywood, M; Molyneux, C; Mahadevan, V; Srinivasaiah, N

2017-12-01

Complete mesocolic excision for right-sided colon cancer may offer an oncologically superior excision compared to traditional right hemicolectomy through high vascular tie and adherence to embryonic planes during dissection, supported by preoperative scanning to accurately define the tumour lymphovascular supply and drainage. The authors support and recommend precision oncosurgery based on these principles, with an emphasis on the importance of understanding the vascular anatomy. However, the anatomical variability of the right colic artery (RCA) has resulted in significant discord in the literature regarding its precise arrangement. We systematically reviewed the literature on the incidence of the different origins of the RCA in cadaveric studies. An electronic search was conducted as per Preferred Reporting Items for Systematic Reviews and Meta-analyses recommendations up to October 2016 using the MESH terms 'right colic artery' and 'anatomy' (PROSPERO registration number CRD42016041578). Ten studies involving 1073 cadavers were identified as suitable for analysis from 211 articles retrieved. The weighted mean incidence with which the right colic artery arose from other parent vessels was calculated at 36.8% for the superior mesenteric artery, 31.9% for the ileocolic artery, 27.7% for the root of the middle colic artery and 2.5% for the right branch of the middle colic artery. In 1.1% of individuals the RCA shared a trunk with the middle colic and ileocolic arteries. The weighted mean incidence of 2 RCAs was 7.0%, and in 8.9% of cadavers the RCA was absent. This anatomical information will add to the technical nuances of precision oncosurgery in right-sided colon resections.

Emission computed tomography using rotating gamma cameras for stress 201Tl myocardial imaging

International Nuclear Information System (INIS)

Takeda, Kan; Maeda, Hisato; Nakagawa, Tsuyoshi; Yamaguchi, Nobuo; Taguchi, Mitsuo

1983-01-01

The purpose of this study is to evaluate the efficacy of emission computed tomography (ECT) for stress 201 Tl myocardial imaging to localize coronary artery disease (CAD) in comparison with planar (PL) images. In a series of 14 normal subjects and 53 patients with CAD proved coronary arteriography, ECT and PL imaging were performed successively. ECT data were collected for 90 projections in a 64 x 64 matrix form with a total aquisition time of 6 munutes over 180 0 of opposed dual cameras ratation and tomographic sections oriented perpendicular and parallel to the long axis of left ventricle were reconstructed. PL images were obtained for left lateral, left anterior oblique (30 0 and 45 0 ) and anterior projections. Both ECT and PL myocardial images were divided into 8 segments and segmental analysis was performed by visual interpretation. The ECT images remarkably increased sensitivity over the PL images in left anterior descending (LAD) artery (from 56% to 76%), right coronary artery (RCA) (from 50% to 96%), and circumflex artery (CX) (from 56% to 69%) lesions. The specificity for ECT images, as compared with PL images, was higher in LAD (88% against 85%) but slightly lower in RCA (70% ag ainst 72%) and CX (84% against 88%). Overall accuracy, therefore, was improved in LAD (from 67% to 81%) and RCA (from 64% to 79%) but equal in CX (81%). We conclude that stress 201 Tl ECT imaging result in a remarkable improvement in the localization of CAD, especially in patients with RCA lesions and multi-vessel disease. (author)

Summation and Cancellation Effects on QRS and ST-Segment Changes Induced by Simultaneous Regional Myocardial Ischemia.

Science.gov (United States)

Vives-Borrás, Miquel; Jorge, Esther; Amorós-Figueras, Gerard; Millán, Xavier; Arzamendi, Dabit; Cinca, Juan

2018-01-01

Simultaneous ischemia in two myocardial regions is a potentially lethal clinical condition often unrecognized whose corresponding electrocardiographic (ECG) patterns have not yet been characterized. Thus, this study aimed to determine the QRS complex and ST-segment changes induced by concurrent ischemia in different myocardial regions elicited by combined double occlusion of the three main coronary arteries. For this purpose, 12 swine were randomized to combination of 5-min single and double coronary artery occlusion: Group 1: left Circumflex (LCX) and right (RCA) coronary arteries ( n = 4); Group 2: left anterior descending artery (LAD) and LCX ( n = 4) and; Group 3: LAD and RCA ( n = 4). QRS duration and ST-segment displacement were measured in 15-lead ECG. As compared with single occlusion, double LCX+RCA blockade induced significant QRS widening of about 40 ms in nearly all ECG leads and magnification of the ST-segment depression in leads V1-V3 (maximal 228% in lead V3, p ST-segment elevation in precordial leads (maximal attenuation of 60% in lead V3 in LAD+LCX and 86% in lead V5 in LAD+RCA, p ST-segment elevation in leads V7-V9 was a specific sign of single LCX occlusion. In conclusion, concurrent infero-lateral ischemia was associated with a marked summation effect of the ECG changes previously elicited by each single ischemic region. By contrast, a cancellation effect on ST-segment changes with no QRS widening was observed when the left anterior descending artery was involved.

A Label-Free and Sensitive Fluorescent Qualitative Assay for Bisphenol A Based on Rolling Circle Amplification/Exonuclease III-Combined Cascade Amplification

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Xia Li

2016-10-01

Full Text Available Bisphenol A (BPA detection in drinking water and food packaging materials has attracted much attention since the discovery that BPA can interfere with normal physiological processes and cause adverse health effects. Here, we constructed a label-free aptamer fluorescent assay for selective and sensitive detection of BPA based on the rolling circle amplification (RCA/Exonuclease III (Exo III-combined cascade amplification strategy. First, the duplex DNA probe (RP with anti-BPA aptamer and trigger sequence was designed for BPA recognition and signal amplification. Next, under the action of BPA, the trigger probe was liberated from RP to initiate RCA reaction as primary amplification. Subsequently, the RCA products were used to trigger Exo III assisted secondary amplification with the help of hairpin probes, producing plenty of “G-quadruplex” in lantern-like structures. Finally, the continuously enriched “G-quadruplex lanterns” were lightened by zinc(II-protoporphyrin IX (ZnPPIX generating enhanced fluorescence signals. By integrating the primary RCA and secondary Exo III mediated cascade amplification strategy, this method displayed an excellent sensitivity with the detection limits of 5.4 × 10−17 M. In addition, the anti-BPA aptamer exhibits high recognition ability with BPA, guaranteeing the specificity of detection. The reporter signal probe (G-quadruplex with ZnPPIX provides a label-free fluorescence signals readout without complicated labeling procedures, making the method simple in design and cost-effective in operation. Moreover, environmental samples analysis was also performed, suggesting that our strategy was reliable and had a great potential application in environmental monitoring.

Regional cooperative agreement for the Asia and Pacific region

International Nuclear Information System (INIS)

Anon.

1981-01-01

Among the means available to the International Atomic Energy Agency to promote cooperative efforts in the nuclear field is the Regional Cooperative Agreement (RCA) for Research, Development, and Training related to Nuclear Science and Technology for the Asia and Pacific Region. Under the terms of this agreement, which came into force on June 12, 1972, participating countries aim to promote and coordinate research, development, and training projects in nuclear fields through collaborative efforts among relevant national institutions in the region. The Agency's role is to provide organizational, administrative, advisory, technical, and financial assistance when needed to secure successful execution of the projects undertaken within the framework of the RCA. Although this presentation deals primarily with the benefits of regional cooperation under the agreement, a review of the RCA would be somewhat imbalanced without a mention of its shortcomings. One of the principal impediments to more rapid progress, as is the case in many other areas, is financing. There is no stable source of funding outside the research contract program and, the likelihood of large-scale UNDP support notwithstanding, a greater willingness on the part of participating Member States to support the program along with the development of a greater sense of common purpose are called for. In this connection serious consideration is being given to the possibility of establishing an Asian Centre for Research and Training, an institute that would bring together scientists from the region to collaborate on problems common to the RCA countries. A study group has already been convened to investigate the feasibility of this proposal

A Label-Free and Sensitive Fluorescent Qualitative Assay for Bisphenol A Based on Rolling Circle Amplification/Exonuclease III-Combined Cascade Amplification.

Science.gov (United States)

Li, Xia; Song, Juan; Xue, Qing-Wang; You, Fu-Heng; Lu, Xia; Kong, Yan-Cong; Ma, Shu-Yi; Jiang, Wei; Li, Chen-Zhong

2016-10-21

Bisphenol A (BPA) detection in drinking water and food packaging materials has attracted much attention since the discovery that BPA can interfere with normal physiological processes and cause adverse health effects. Here, we constructed a label-free aptamer fluorescent assay for selective and sensitive detection of BPA based on the rolling circle amplification (RCA)/Exonuclease III (Exo III)-combined cascade amplification strategy. First, the duplex DNA probe (RP) with anti-BPA aptamer and trigger sequence was designed for BPA recognition and signal amplification. Next, under the action of BPA, the trigger probe was liberated from RP to initiate RCA reaction as primary amplification. Subsequently, the RCA products were used to trigger Exo III assisted secondary amplification with the help of hairpin probes, producing plenty of "G-quadruplex" in lantern-like structures. Finally, the continuously enriched "G-quadruplex lanterns" were lightened by zinc(II)-protoporphyrin IX (ZnPPIX) generating enhanced fluorescence signals. By integrating the primary RCA and secondary Exo III mediated cascade amplification strategy, this method displayed an excellent sensitivity with the detection limits of 5.4 × 10 -17 M. In addition, the anti-BPA aptamer exhibits high recognition ability with BPA, guaranteeing the specificity of detection. The reporter signal probe (G-quadruplex with ZnPPIX) provides a label-free fluorescence signals readout without complicated labeling procedures, making the method simple in design and cost-effective in operation. Moreover, environmental samples analysis was also performed, suggesting that our strategy was reliable and had a great potential application in environmental monitoring.

Improved Focusing Method for 3-D Imaging using Row–Column-Addressed 2-D Arrays

DEFF Research Database (Denmark)

Bouzari, Hamed; Engholm, Mathias; Stuart, Matthias Bo

2017-01-01

A row–column-addressed (RCA) 2-D array can be interpreted as two orthogonal 1-D arrays. By transmitting with row elements and receiving the echoes through column elements or vice versa, a rectilinear volume in front of the array can be beamformed. Since the transmit and receive 1-D arrays are ort...... measurements with a PZT λ/2-pitch 3 MHz 62+62 RCA 2-D transducer probe. A synthetic aperture imaging sequence with single element transmissions at a time, is designed for imaging down to 14 cm at a volume rate of 44 Hz....

Learning Team Breach of a Posted Barricade to Connect an Instrument to Power

Energy Technology Data Exchange (ETDEWEB)

Wilburn, Dianne Williams [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

2017-04-19

On February 15, 2017, a DESHF-STO HPFC (health physics field coordinator) was asked by an NEN-1 employee if they could move an instrument, a radiation dosimetry system, from A166A to another lab at TA-35 Building 2. The HPFC walked the job down and discovered the instrument was connected to power. The instrument had not been connected to power previously. See photo 1. The instrument is located within an RCA (radiological control area). Entry to connect the instrument to power the instrument requires contacting RP. RP personnel had not been contacted as required as stated in the RCA posting.

Biological Inspiration for Agile Autonomous Air Vehicles

Science.gov (United States)

2007-11-01

half of one wing, bees with legs packed with pollen , butterflies or moths with torn and frayed wings likewise are capable of apparently normal flight...technologies. To appreciate this, consider a not unreasonable extension of a wide area autonomous search (WAAS) munition operational scenario. Here...detect and destroy missile launchers that are operating in the back alleys of an urban areas or search Evers, J.H. (2007) Biological Inspiration for Agile

Economic Liberalism and Regional Security in East Asia: A Case Study on the Impact of China’s Accession to the WTO

Science.gov (United States)

2010-12-10

And finally, I save the last word for Mrs. Venita Krueger whom I believe has the entire Turabian manual stored in her memory, and whose meticulousness...telecommunications, financial services, agriculture, retail , and entertainment sectors. Other political issues that were thrown into the fray and...finance. In contrast, middle-income countries such as Indonesia, Malaysia , and Thailand were expected to receive a mixed impact due to their similarity in

A Question of Heroines

Directory of Open Access Journals (Sweden)

Jaime Oscar M. Salazar

2014-06-01

Full Text Available Ang Kababaihan ng Malolos (2014. 85 minutes. Color. Directed by Sari Dalena and Kiri Dalena. Written and produced by Nicanor Tiongson. Cinematography by Kiri Dalena. Starring Hazel Faith dela Cruz as Basilia Villariño Tantoco, Karl Medina as Jose Rizal, Bong Enriquez as Governor-General Valeriano Weyler, and Carlos Celdran as Fray Felipe Garcia. Edited by Keith Sicat and Joris Fernandez. Philippines: Ambassador Bienvenido R. Tantoco Sr.

JOINT ADVISORY APPEALS BOARD

CERN Multimedia

Personnel Division

1999-01-01

The Joint Advisory Appeals Board was convened to examine the appeal lodged by Mr Joào Bento with regard to residential category. As the appellant has not objected, the recommendations of the Board and the final decision of the Director-General are brought to the notice of the personnel in accordance with Article RÊVIÊ1.20 of the Staff Regulations.The relevant documents will therefore be posted on the notice boards of the Administration Building (N¡ 60) from 29 October to 12 November 1999.Personnel DivisionTel. 74128

Casa Camelo - quando a casa se adéqua ao meio: proposta arquitetônica para residência unifamiliar de alto padrão levando em consideração aspectos ambientais sustentáveis de gestão de água, energia e condicionantes bioclimáticas

OpenAIRE

Macedo, André Luiz Gomes de

2016-01-01

Esse trabalho envolve pesquisas recentes que levantam prescrições técnicas para se projetar residências unifamiliares de alto padrão, suprindo uma lacuna sustentável específica em se absorver, compreender e inserir alguns desses conceitos complementares às formas tradicionais de se habitar, aqui destacado como algo que sucedeu o ato de projetar e construir. O surgimento de uma demanda de um projeto a ser confeccionado na cidade de Serra de São Bento, a 130 km de Natal-RN trouxe...

On the biophysics and kinetics of toehold-mediated DNA strand displacement.

Science.gov (United States)

Srinivas, Niranjan; Ouldridge, Thomas E; Sulc, Petr; Schaeffer, Joseph M; Yurke, Bernard; Louis, Ard A; Doye, Jonathan P K; Winfree, Erik

2013-12-01

Dynamic DNA nanotechnology often uses toehold-mediated strand displacement for controlling reaction kinetics. Although the dependence of strand displacement kinetics on toehold length has been experimentally characterized and phenomenologically modeled, detailed biophysical understanding has remained elusive. Here, we study strand displacement at multiple levels of detail, using an intuitive model of a random walk on a 1D energy landscape, a secondary structure kinetics model with single base-pair steps and a coarse-grained molecular model that incorporates 3D geometric and steric effects. Further, we experimentally investigate the thermodynamics of three-way branch migration. Two factors explain the dependence of strand displacement kinetics on toehold length: (i) the physical process by which a single step of branch migration occurs is significantly slower than the fraying of a single base pair and (ii) initiating branch migration incurs a thermodynamic penalty, not captured by state-of-the-art nearest neighbor models of DNA, due to the additional overhang it engenders at the junction. Our findings are consistent with previously measured or inferred rates for hybridization, fraying and branch migration, and they provide a biophysical explanation of strand displacement kinetics. Our work paves the way for accurate modeling of strand displacement cascades, which would facilitate the simulation and construction of more complex molecular systems.

Santa Teresa y sus cartas, historia de los sentimientos

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Egido, Teófanes

2015-12-01

Full Text Available Historical reflection on a peculiar dimension of St. Teresa of Jesus: the expression of her feelings in her writings, particularly in her abundant letters. The article focuses on the sense of humor, the joyfulness, and the importance of laughter in St. Teresa language, and also on the feeling of endearment with her family, with her order, with fray Juan de la Cruz. Ample space is dedicated to the tenderness towards girls in her convents. St. Teresa of Jesus appears as transgressor of 16th century social behaviours.Reflexión histórica sobre una dimensión peculiar de santa Teresa de Jesús: la expresión de sus sentimientos en sus escritos, de forma más especial en sus cartas abundantes. El artículo se centra en el sentido del humor, de la alegría, en la importancia de la risa en el lenguaje de santa Teresa y en el sentimiento de ternura con su familia, con su orden, con fray Juan de la Cruz. Se dedica un espacio amplio a la ternura hacia las niñas en sus conventos. Aparece santa Teresa de Jesús como trasgresora de los comportamientos sociales del siglo XVI.

¿Un inédito de Guido Reni en Ávila?

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Esteban Ángel Cotillo Torrejón

2006-01-01

Full Text Available Aún en esta época vemos como el catálogo de los grandes maestros se amplía con nuevos hallazgos. No está lejano el descubrimiento del «Retrato de dama» del Tiziano, o el Caravaggio que yacía olvidado en los almacenes del británico palacio de Hampton Court, o las dos tablas de Fray Angélico, ambas de pequeño formato, que reaparecieron en Gran Bretaña. Por ello, es importante dar a conocer el lienzo que ignorado y anónimo cuelga de las paredes catedralicias abulenses, posiblemente estemos ante una obra de Guido Reni, o al menos, de su escuela.Even at this time we can see as the catalogue of the great painters is extending with new findings. The discovery of Tiziano’s Portrait of a lady, or a Caravaggio that laid forgotten in the British Palace of Hampton Court warehouses, or Fray Angelico’s two tables, both of small formats, that reappeared in Great Britain. For that reason, it is important to present the painting, that ignored and anonymous, hangs of the Avila’s Catedral walls, possibly we are in front of a work of Guido Reni, or at least their school.

Estructuras laminares en España

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Coello de Portugal, Fray

1968-02-01

Full Text Available This article deals with three interesting thin shell structures that serve as roofs for churches in various parts of Spain. The excellent functional properties of these shells is worth noting as well as their spectacular aspect and relatively low cost, especially if their complex geometry and striking structural effectiveness are taken into account. The Portuguese architect Fray Coello provided the general pattern of the designs, and the firm Construcciones Laminares, S. L., was responsible for the supervision of the construction, the calculations, plans, details and the actual construction. This paper was submited to lASS, 1967, in Mexico.Se exponen aquí tres interesantes cubiertas laminares para respectivas iglesias situadas en diferentes puntos de la geografía hispana. Se han de resaltar sus magníficos resultados y comportamiento, así como la gran espectacularidad conseguida y su bajo costo relativo, sobre todo a la vista de la plasticidad formal y el dramatismo estructural de las soluciones adoptadas. El arquitecto Fray Coello de Portugal aportó las ideas generales de diseño, encargándose el proyecto, supervisión, cálculo, planos, detalles, e incluso la construcción en algunos casos, a Construcciones Laminares, S. L. Este trabajo fue presentado en la IASS-1967 de México.

Seletividade de inseticidas usados na cultura da macieira a duas populações de Chrysoperla externa (Hagen, 1861 (Neuroptera: Chrysopidae Selectivity of insecticides used in apple orchards to two populations of Chrysoperla externa (Hagen, 1861 (Neuroptera: Chrysopidae

Directory of Open Access Journals (Sweden)

Antônio José Ferreira

2006-04-01

Full Text Available Neste trabalho, foi avaliado o efeito de inseticidas sobre larvas de duas populações de Chrysoperla externa (Hagen, 1861 (Neuroptera: Chrysopidae, oriundas de pomares de Bento Gonçalves e Vacaria, RS. O trabalho foi realizado em laboratório (25±2°C, UR de 70±10% e fotofase de 12 horas avaliando-se inseticidas, nas concentrações indicadas pelos fabricantes e/ou que estão em fase de pesquisa para o controle da mariposa oriental, lagarta enroladeira e mosca-das-frutas na cultura da macieira. Os inseticidas e dosagens (g ou mL do p.c./100L de água avaliados foram: fosmet (Imidan 500 PM - 200, metoxifenozide (Intrepid 240 SC - 60, tebufenozide (Mimic 240 SC - 60, benzoato de emamectina (Proclaim 5 SG - 15, spinosad (Tracer 480 SC - 20, etofenprox (Trebon 100 SC - 150, clorpirifós etil (Lorsban 480 BR - 150 e testemunha (somente água. As pulverizações foram realizadas em larvas de primeiro ínstar utilizando torre de Potter. Avaliaram-se a sobrevivência e a duração das fases de larva e pupa e, a fecundidade e a fertilidade dos adultos sobreviventes. A toxicidade dos produtos foi calculada em função do efeito total (E de cada produto, conforme recomendações da IOBC. Para larvas de primeiro ínstar do crisopídeo oriundas de Bento Gonçalves, benzoato de emamectina, foi classificado como inofensivo (classe 1; metoxifenozide, etofenprox, tebufenozide, spinosad e fosmet, como levemente nocivos (classe 2 e clorpirifós, como nocivo (classe 4. Já para a população larval de C. externa de Vacaria, benzoato de emamectina, metoxifenozide, etofenprox, tebufenozide e spinosad foram inofensivos; fosmet mostrou-se moderadamente nocivo (classe 3 e clorpirifós foi nocivo.The effect of some insecticides on larvae of two populations of Chrysoperla externa (Hagen, 1861 (Neuroptera: Chrysopidae from Bento Gonçalves and Vacaria, RS were evaluated under laboratory conditions (25±2°C, RH of 70±10% and 12 hours-photophase. The compounds were

Defining carbohydrate specificity of Ricinus communis agglutinin as Gal beta 1-->4GlcNAc (II) > Gal beta 1-->3GlcNAc (I) > Gal alpha 1-->3Gal (B) > Gal beta 1-->3GalNAc (T).

Science.gov (United States)

Wu, J H; Herp, A; Wu, A M

1993-03-01

To define carbohydrate specificity of Ricinus communis agglutinin (RCA1), the combining site of RCA1 was further characterized by quantitative precipitin (QPA) and precipitin-inhibition assays (QPIA). Among the oligosaccharides tested for QPIA, Gal beta 1-->4GlcNAc (II, human blood group type II precursor sequence) was found to be 7.1 times more active than Gal beta 1-->3GalNAc (T, Thomsen-Friedenreich sequence) and about 1.7 times more active than the other three disaccharides tested--Gal beta 1-->4Man, Gal beta 1-->3DAra and Gal beta 1-->6GalNAc. Gal alpha 1-->4Gal, the receptor of the uropathogenic E. coli ligand was 3.6 times less active than the II sequence. These results indicate that the beta 1-->4 linkage of the terminal Gal to subterminal GlcNAc is important as this beta 1-->4GlcNAc sequence is at least 1.6 times more active than other types of disaccharides. Among the glycoproteins examined for QPA, native and desialized bovine submandibular glycoproteins, native and desialized human plasma alpha 1-acid glycoproteins, as well as crude hog stomach mucin and its three mild acid hydrolyzed products reacted well with the lectin. These glycoproteins precipitated over 75% of the lectin nitrogen added indicating that RCA1 has the ability to recognize Gal beta 1-->4/3GlcNAc and/or the related residues at the non-reducing ends and at positions in the interior of the chains. However, Tn (GalNAc alpha 1-->Ser/Thr sequence) rich glycoproteins such as desialized ovine submandibular glycoprotein and desialized armadillo salivary glycoprotein, in which over 90% of the carbohydrate side chains are Tn determinants with none or only a trace of I/II or T determinants, precipitated poorly with RCA1. From the present and previous results obtained, the carbohydrate specificity of RCA1 can be constructed and summarized in decreasing order by lectin determinants as follows: II (Gal beta 1-->4GlcNAc) > I (Gal beta 1-->3GlcNAc) > E (Gal alpha 1-->4Gal) and B (Gal alpha 1-->3Gal

Biochemical enrichment and biophysical characterization of a taste receptor for L-arginine from the catfish, Ictalurus puntatus

Directory of Open Access Journals (Sweden)

Spielman Andrew I

2004-07-01

Full Text Available Abstract Background The channel catfish, Ictalurus punctatus, is invested with a high density of cutaneous taste receptors, particularly on the barbel appendages. Many of these receptors are sensitive to selected amino acids, one of these being a receptor for L-arginine (L-Arg. Previous neurophysiological and biophysical studies suggested that this taste receptor is coupled directly to a cation channel and behaves as a ligand-gated ion channel receptor (LGICR. Earlier studies demonstrated that two lectins, Ricinus communis agglutinin I (RCA-I and Phaseolus vulgaris Erythroagglutinin (PHA-E, inhibited the binding of L-Arg to its presumed receptor sites, and that PHA-E inhibited the L-Arg-stimulated ion conductance of barbel membranes reconstituted into lipid bilayers. Results Both PHA-E and RCA-I almost exclusively labeled an 82–84 kDa protein band of an SDS-PAGE of solubilized barbel taste epithelial membranes. Further, both rhodamine-conjugated RCA-I and polyclonal antibodies raised to the 82–84 kDa electroeluted peptides labeled the apical region of catfish taste buds. Because of the specificity shown by RCA-I, lectin affinity was chosen as the first of a three-step procedure designed to enrich the presumed LGICR for L-Arg. Purified and CHAPS-solubilized taste epithelial membrane proteins were subjected successively to (1, lectin (RCA-I affinity; (2, gel filtration (Sephacryl S-300HR; and (3, ion exchange chromatography. All fractions from each chromatography step were evaluated for L-Arg-induced ion channel activity by reconstituting each fraction into a lipid bilayer. Active fractions demonstrated L-Arg-induced channel activity that was inhibited by D-arginine (D-Arg with kinetics nearly identical to those reported earlier for L-Arg-stimulated ion channels of native barbel membranes reconstituted into lipid bilayers. After the final enrichment step, SDS-PAGE of the active ion channel protein fraction revealed a single band at 82–84 k

Citrate Anticoagulation during Continuous Renal Replacement Therapy.

Science.gov (United States)

Ricci, Davide; Panicali, Laura; Facchini, Maria Grazia; Mancini, Elena

2017-01-01

During extracorporeal dialysis, some anticoagulation strategy is necessary to prevent the coagulation of blood. Heparin has historically been used as an anticoagulant because of its efficacy combined with low cost. However, a variable incidence of hemorrhagic complications (5-30%) has been documented in patients undergoing continuous renal replacement therapy (CRRT) with heparin as an anticoagulant. Citrate has anticoagulation properties secondary to its ability to chelate calcium, which is necessary for the coagulation cascade. Citrate may thus be used in a regional anticoagulation (RCA), limited to the extracorporeal circuit of CRRT, to avoid systemic anticoagulation. Recent meta-analysis confirmed the advantage of RCA over heparin in terms of incidence of bleeding during CRRT. Moreover, an increase in filter lifespan is documented, with a secondary advantage in reaching the prescribed dialysis dose. In our experience, we could confirm this positive effect. In fact, with a progressive increase in the proportion of CRRT with citrate as RCA, we obtained a reduction in the number of filters used for every 72 h of treatment (from 2.4 in 2011 to 1.3 in 2015), and most importantly, a reduction in the difference between the prescribed and delivered dialysis doses (from 22 to 7%). Citrate has an intense effect on the acid-base balance as well, if fully metabolized through the Krebs cycle, due to the production of bicarbonate. Even more severely ill patients, such as those with liver dysfunction, may be treated with RCA without severe complications, because modern machines for CRRT are equipped with simple systems that are able to manage the citrate infusion and control the calcium levels, with minimal risks of metabolic derangements. © 2017 S. Karger AG, Basel.

Effects of extraction methods and factors on leaching of metals from recycled concrete aggregates.

Science.gov (United States)

Bestgen, Janile O; Cetin, Bora; Tanyu, Burak F

2016-07-01

Leaching of metals (calcium (Ca), chromium (Cr), copper, (Cu), iron (Fe), and zinc (Zn)) of recycled concrete aggregates (RCAs) were investigated with four different leachate extraction methods (batch water leach tests (WLTs), toxicity leaching procedure test (TCLP), synthetic precipitation leaching procedure test (SPLP), and pH-dependent leach tests). WLTs were also used to perform a parametric study to evaluate factors including (i) effects of reaction time, (ii) atmosphere, (iii) liquid-to-solid (L/S) ratio, and (iv) particle size of RCA. The results from WLTs showed that reaction time and exposure to atmosphere had impact on leaching behavior of metals. An increase in L/S ratio decreased the effluent pH and all metal concentrations. Particle size of the RCA had impact on some metals but not all. Comparison of the leached concentrations of metals from select RCA samples with WLT method to leached concentrations from TCLP and SPLP methods revealed significant differences. For the same RCA samples, the highest metal concentrations were obtained with TCLP method, followed by WLT and SPLP methods. However, in all tests, the concentrations of all four (Cr, Cu, Fe, and Zn) metals were below the regulatory limits determined by EPA MCLs in all tests with few exceptions. pH-dependent batch water leach tests revealed that leaching pattern for Ca is more cationic whereas for other metals showed more amphoteric. The results obtained from the pH-dependent tests were evaluated with geochemical modeling (MINTEQA2) to estimate the governing leaching mechanisms for different metals. The results indicated that the releases of the elements were solubility-controlled except Cr.

Enhanced direct-gap light emission from Si-capped n+-Ge epitaxial layers on Si after post-growth rapid cyclic annealing: impact of non-radiative interface recombination toward Ge/Si double heterostructure lasers.

Science.gov (United States)

Higashitarumizu, Naoki; Ishikawa, Yasuhiko

2017-09-04

Enhanced direct-gap light emission is reported for Si-capped n + -Ge layers on Si after post-growth rapid cyclic annealing (RCA), and impact of non-radiative recombination (NRR) at the Ge/Si interface is discussed toward Ge/Si double heterostructure (DH) lasers. P-doped n + -Ge layer (1 × 10 19 cm -3 , 400 nm) is grown on Si by ultra-high vacuum chemical vapor deposition, followed by a growth of Si capping layer (5 nm) to form a Si/Ge/Si DH structure. Post-growth RCA to eliminate defects in Ge is performed in N 2 at temperatures between 900°C and 780°C, where the annealing time is minimized to be 5 s in each RCA cycle to prevent an out-diffusion of P dopants from the Ge surface. Direct-gap photoluminescence (PL) intensity at 1.6 µm increases with the RCA cycles up to 40, although the threading dislocation density in Ge is not reduced after 3 cycles in the present condition. The PL enhancement is ascribed to the suppression of NRR at the Ge/Si interface, where an intermixed SiGe alloy is formed. For Ge/Si DH lasers, NRR at the Ge/Si interface is found to have a significant impact on the threshold current density Jth. In order to achieve Jth on the order of 1 kA/cm 2 , similar to III-V lasers, the interface recombination velocity S is required below 10 3 cm/s in spite of S as large as 10 5 cm/s at the ordinary defect-rich Ge/Si interface.

An extracardiac unruptured right sinus of valsalva aneurysm complicated with atherothrombosis

Directory of Open Access Journals (Sweden)

Jun Zhang

2016-04-01

Full Text Available We present quite a rare case of extracardiac unruptured right sinus of valsalva aneurysm (SVA complicated with atherothrombosis in a young adult man. A 35-year-old male with a giant unruptured SVA arising from the right coronary sinus (RCS with extracardiac protrusion was diagnosed by echocardiography. Contrast-enhanced computed tomography (CT revealed a huge calcified aneurysm with mural thrombi originating from the aortic root, and about 80% stenosis at the initial segment of the right coronary artery (RCA. Intraoperative exploration demonstrated a giant unruptured aneurysm arising from the RCS. Different from other SVAs reported before, this aneurismal wall appeared thick and atheromatous-like. In this aneurysm, there was a small localized intima tearing and mural thrombosis, and the orifice of the RCA was almost blocked. This patient underwent surgical patch repair to prevent aneurysm rupture and coronary artery bypass grafting for RCA revascularization. In conclusion, the pathological examination demonstrated marked foam cells, inflammatory cells, and thrombosis in the aneurismal wall. Learning points: • Echocardiographic characteristics of sinus of valsalva aneurysm (SVA. • Diagnostic evaluation of extracardiac unruptured SVA. • Pathology of rare SVA.

A Case Report of Coronary Arteriovenous Fistulas with an Unruptured Coronary Artery Aneurysm Successfully Treated by Surgery

Directory of Open Access Journals (Sweden)

Nobuhiro Takeuchi

2012-01-01

Full Text Available A 58-year-old female with a history of Wolff-Parkinson-White syndrome presented at our institution with palpitations and chest pain. Electrocardiography revealed paroxysmal supraventricular tachycardia with a heart rate of 188 beats/min. Antiarrhythmic drugs were ineffective, and tachycardia was resolved by electrical cardioversion. Transthoracic echocardiography revealed abnormal vessels around the right coronary artery (RCA and pulmonary artery (PA; in addition, we suspected coronary arteriovenous fistula (CAVF. Coronary angiography and coronary computed tomography revealed dilated fistula vessels, with a 1 cm saccular aneurysm around the RCA, originating from the proximal RCA and left anterior descending artery into the main trunk of PA. Therefore, we confirmed the diagnosis of CAVF with an unruptured aneurysm. We surgically ligated and clipped the fistula vessels and resected the aneurysm. The resected aneurysm measured  cm in size. Pathological examination of the resected aneurysm revealed hypertrophic walls comprising proliferating fibroblasts cells thin elastic fibers. Very few atherosclerotic changes manifested in the aneurysm walls. We report the case of a patient with CAVF and an unruptured coronary artery aneurysm who was successfully treated by surgery.

Ion balance and acidity of size-segregated particles during haze episodes in urban Beijing

Science.gov (United States)

Tian, Shili; Pan, Yuepeng; Wang, Yuesi

2018-03-01

In this study, we investigated how the ion balance causes variations in size segregated aerosol acidity and atmospheric processing on clean versus hazy days using a 9-stage sampler. We calculated the ratios (in charge equivalents, RC/A) between measured cations (Na+, NH4+, K+, Mg2 +, and Ca2 +) and anions (SO42 -, NO3- and Cl-) for different aerosol size fractions. The ratios were typically close to unity in the accumulation mode (0.65-2.1 μm), and increased significantly when the particle size increased or decreased. In the coarse size range (aerodynamic diameter > 2.1 μm), high RC/A values were most likely caused by the undetermined CO32- and HCO3- content of the mineral dust. In contrast, the high RC/A values for submicron aerosols (NH4+ (SNA) and concentrations of SNA increased with the increasing aerosol acidity. Significant correlations between [NO3-]/[SO42 -] and [NH4+]/[SO42 -] during NH4+-rich conditions in fine size fractions indicated fine mode NO3- in Beijing was mainly formed by gas-phase homogeneous reaction between the ambient NH3 and HNO3.

Recommended Immunological Assays to Screen for Ricin-Containing Samples

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Stéphanie Simon

2015-11-01

Full Text Available Ricin, a toxin from the plant Ricinus communis, is one of the most toxic biological agents known. Due to its availability, toxicity, ease of production and absence of curative treatments, ricin has been classified by the Centers for Disease Control and Prevention (CDC as category B biological weapon and it is scheduled as a List 1 compound in the Chemical Weapons Convention. An international proficiency test (PT was conducted to evaluate detection and quantification capabilities of 17 expert laboratories. In this exercise one goal was to analyse the laboratories’ capacity to detect and differentiate ricin and the less toxic, but highly homologuous protein R. communis agglutinin (RCA120. Six analytical strategies are presented in this paper based on immunological assays (four immunoenzymatic assays and two immunochromatographic tests. Using these immunological methods “dangerous” samples containing ricin and/or RCA120 were successfully identified. Based on different antibodies used the detection and quantification of ricin and RCA120 was successful. The ricin PT highlighted the performance of different immunological approaches that are exemplarily recommended for highly sensitive and precise quantification of ricin.

Sub-Saharan Africa Report, No. 2826

Science.gov (United States)

1983-07-27

Begins Housing Sales to Blacks (Johannesburg Domestic Service, 1 Jul 83) 79 Roles of Black Farmers, U.S. Firms Discussed (SAPA, 7 Jul 83...advanced technology and superpowers. Yet how many in Africa will share his sentiment if only because it is a necessary subject about which to talk and...some of the shocks, and prevent a dangerous internationalisation . Col. Mengistu, the new OAU Chairman, who has entered the fray to criticise Zaire’s

Ressenyes

OpenAIRE

Fernández Terricabras, Ignasi

2008-01-01

Index de les obres ressenyades: Fray Tomás GOMEZ, En reino extraño. Relación de la visita del Real Monasterio de Valldigna. Autobiografía, vida cotidiana y lucha política en la España de Carlos II. Edición crítica y estudios de Fernando Andrés Robres, Rafael Benítez Sánchez-Blanco y Eugenio Císcar Pallarés

Effects of radiation therapy on growing long bones

International Nuclear Information System (INIS)

De Smet, A.A.; Kuhns, L.R.; Fayos, J.V.; Holt, J.F.

1976-01-01

Characteristic radiographic changes were seen in six of 14 children who received radiation therapy to the epiphyseal plate of a long bone. These changes, which include metaphyseal sclerosis, metaphyseal fraying, and epiphyseal plate widening, resemble rickets. In three patients, these changes were followed by development of a broad metaphyseal band of increased density. The absence of metaphyseal changes may indicate sterilization of cartilage cells and may be predictive of significant limb shortening

Design of Low-Complexity and High-Speed Coplanar Four-Bit Ripple Carry Adder in QCA Technology

Science.gov (United States)

Balali, Moslem; Rezai, Abdalhossein

2018-03-01

Quantum-dot Cellular Automata (QCA) technology is a suitable technology to replace CMOS technology due to low-power consumption, high-speed and high-density devices. Full adder has an important role in the digital circuit design. This paper presents and evaluates a novel single-layer four-bit QCA Ripple Carry Adder (RCA) circuit. The developed four-bit QCA RCA circuit is based on novel QCA full adder circuit. The developed circuits are simulated using QCADesigner tool version 2.0.3. The simulation results show that the developed circuits have advantages in comparison with existing single-layer and multilayer circuits in terms of cell count, area occupation and circuit latency.

Endothelial Dysfunction in Resuscitated Cardiac Arrest (ENDO-RCA)

DEFF Research Database (Denmark)

Meyer, Anna Sina P; Ostrowski, Sisse Rye; Kjærgaard, Jesper

2016-01-01

BACKGROUND: Morbidity and mortality following initial survival of cardiac arrest remain high despite great efforts to improve resuscitation techniques and post-resuscitation care, in part due to the ischemia-reperfusion injury secondary to the restoration of the blood circulation. Patients resusc...

F--Ray: A new algorithm for efficient transport of ionizing radiation

Science.gov (United States)

Mao, Yi; Zhang, J.; Wandelt, B. D.; Shapiro, P. R.; Iliev, I. T.

2014-04-01

We present a new algorithm for the 3D transport of ionizing radiation, called F2-Ray (Fast Fourier Ray-tracing method). The transfer of ionizing radiation with long mean free path in diffuse intergalactic gas poses a special challenge to standard numerical methods which transport the radiation in position space. Standard methods usually trace each individual ray until it is fully absorbed by the intervening gas. If the mean free path is long, the computational cost and memory load are likely to be prohibitive. We have developed an algorithm that overcomes these limitations and is, therefore, significantly more efficient. The method calculates the transfer of radiation collectively, using the Fast Fourier Transform to convert radiation between position and Fourier spaces, so the computational cost will not increase with the number of ionizing sources. The method also automatically combines parallel rays with the same frequency at the same grid cell, thereby minimizing the memory requirement. The method is explicitly photon-conserving, i.e. the depletion of ionizing photons is guaranteed to equal the photoionizations they caused, and explicitly obeys the periodic boundary condition, i.e. the escape of ionizing photons from one side of a simulation volume is guaranteed to be compensated by emitting the same amount of photons into the volume through the opposite side. Together, these features make it possible to numerically simulate the transfer of ionizing photons more efficiently than previous methods. Since ionizing radiation such as the X-ray is responsible for heating the intergalactic gas when first stars and quasars form at high redshifts, our method can be applied to simulate thermal distribution, in addition to cosmic reionization, in three-dimensional inhomogeneous cosmological density field.

Base Pair Fraying in Molecular Dynamics Simulations of DNA and RNA

Czech Academy of Sciences Publication Activity Database

Zgarbová, M.; Otyepka, Michal; Šponer, Jiří; Lankaš, Filip; Jurečka, P.

2014-01-01

Roč. 10, č. 8 (2014), s. 3177-3189 ISSN 1549-9618 Grant - others:GA ČR(CZ) GP14-29874P Institutional support: RVO:68081707 ; RVO:61388963 Keywords : QUANTUM-CHEMICAL COMPUTATIONS * NUCLEIC-ACID STRUCTURES * AMBER FORCE-FIELD Subject RIV: BO - Biophysics; CC - Organic Chemistry (UOCHB-X) Impact factor: 5.498, year: 2014

Rituals in Death and Dying: Modern Medical Technologies Enter the Fray

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Michael Gordon

2015-01-01

Full Text Available In the absence of immortality, the human species has over the millennia developed rites and rituals to help in the passing of life to honor the person who is dying or has died or in some way demonstrate their “courage” and perseverance as well as duty even in the face of almost certain death. The centuries-old traditions of the gathering of loved ones, the chanting of prayers, the ritual religious blessings are in the process of being replaced by the “miracles” of modern medical technology.

Training of tissue bank operators in Asia Pacific region

International Nuclear Information System (INIS)

Aziz Nather

1999-01-01

To raise quality standards of Tissue Bank in Asia Pacific Region and to meet training needs of tissue bank operators. Singapore (NUH Tissue Bank) was officially appointed by IAEA on 18 September 1996 in Vienna to be the IAEA/NUS Regional Training Centre for RCA (Regional Co-operative Agreement). Member of States including Bangladesh, China, India, Indonesia, Korea, Malaysia, Myanmar, Pakistan, Philippines, Thailand, Sri Lanka and Vietnam. The Singapore Ministry of Environment gave a grant of $225,500 for setting up of this centre with National Science and Technology Board as funding agency, $100,000 being allocated for production of IAEA Developed Curriculum into Multi-Media. (authors being National Project Co-ordinators, Directors of Tissue Banks in the region). The Modules included Guide to Curriculum, Historical Background (0), Rules and Regulation (1), Organisation (2), Quality Assurance (3), Procurement (4), Processing (5), Distribution and Utilisation (6) and Future Developments (7). The Distance Learning Package included case studies from the region in text, in slides and videotapes. A new purpose-built NUH Tissue Bank with separate Wet and Dry Processing laboratories equipped with hands-on facilities was completed in July 1997. This was inaugurated as; IAEA/NUS Regional Training Centre for RCA; IAEA/NUS Interregional Training Centre; and NUS Diploma Course on Tissue Banking also launched by Deputy vice-chancellor, NUS, in conjunction with the IAEA/RCA Regional Training Course on 3 November 1997. One year NUS Open Distance Learning Diploma Course started with two weeks Intensive Course with Core Lectures on Modules (0-7) in the Curriculum and Practical Hands-on Demonstrations. One theory and two practical assessments were conducted. Nineteen participants registered for the Diploma Course. Production of IAEA Multi-Media Curriculum was completed and the Curriculum was distributed to member States during a 2-week-RCA 'Train the Trainers' Workshop on 27 April

Ecology of the Baia da Babitonga landscape. A cooperative model project of Bavaria and Brazil. Contributions of Erlangen University; Zur Landschaftsoekologie der Baia da Babitonga. Ein brasilianisch-bayerisches Modellprojekt. Beitraege aus Erlanger Fakultaeten

Energy Technology Data Exchange (ETDEWEB)

NONE

2004-07-01

Brazil, with its sensitive ecology and large rainforests, has a key role in the global environmental problem. Bavaria and Brazil have a long tradition of economic and scientific cooperation. For this reason, it appears logical that the 'Babitonga 2000' project was initiated by the Universities of Erlangen-Nuremberg and Univille, Joinville, in the southern province of Santa Catarina. There was also a regular exchange of scientists and students. Two research stations are operated in the bay of Baia da Babitonga and in the rainforest of Sao Bento do Sul. (orig.) [German] Im vorliegenden Band der Erlanger Forschungen wird ueber das interdisziplinaere bayerisch-brasilianische Umweltprojekt ''Babitonga 2000'' berichtet. Brasilien kommt mit seiner sensiblen Umwelt und den grossen Regenwaldarealen im Rahmen der globalen Umweltproblematik eine besondere Bedeutung zu. Bayern und Brasilien verbindet eine lange Tradition wirtschaftlicher und wissenschaftlicher Zusammenarbeit, die heute auf vielfaeltige Weise gefoerdert wird. Somit lag die vor einigen Jahren angebahnte Partnerschaft zwischen den Universitaeten Erlangen-Nuernberg und der brasilianischen Universitaet Univille in Joinville (in der Suedprovinz Santa Catarina) im beiderseitigen Interesse einer Forschungskooperation. Ueber das Projekt ''Babitonga 2000'' hinaus ist es zu einem regen Austausch von Wissenschaftlern und Studenten gekommen. Brasilianische Studenten nutzen die neu geschaffenen MSc- und PhD-Studiengaenge in Erlangen zu ihrer Qualifizierung. Umgekehrt finden deutsche Wissenschaftler und Studenten im Rahmen von Promotionen und Diplomarbeiten interessante Betaetigungsfelder und ausgezeichnete Rahmenbedingungen im Raum Joinville. Besondere Bedeutung kommt dabei den beiden Forschungsstationen der Univille an der Baia da Babitonga und im Regenwald von Sao Bento do Sul zu. (orig.)

Toxicological and ultrastructural analysis of the impact of pesticides used in temperate fruit crops on two populations of Chrysoperla externa (Neuroptera, Chrysopidae

Directory of Open Access Journals (Sweden)

Alexandre Pinho de Moura

2011-09-01

Full Text Available This study aimed to evaluate the effects of (g a.i. L-1 abamectin (0.02, carbaryl (1.73, sulphur (4.8, fenitrothion (0.75, methidathion (0.4, and trichlorfon (1.5 on the survival of larvae and pupae, on the oviposition of adults and hatching of eggs from treated Chrysoperla externa third-instar larvae from two different populations (Bento Gonçalves and Vacaria, Rio Grande do Sul State, Brazil. Morphological changes caused by abamectin to eggs laid by C. externa from Vacaria population were evaluated by mean of ultrastructural analysis. The pesticides were applied on glass plates. Distilled water was used as control. For the evaluation of larvae mortality, a fully randomized experimental design in a 2 x 7 (two populations x seven treatments factorial scheme was used, whereas for the effects of the compounds on oviposition capacity and egg viability, a 2 x 4 factorial scheme was used. Carbaryl, fenitrothion, and methidathion caused 100% mortality of larvae. Abamectin reduced the hatching of eggs from treated third-instar larvae of both populations; however, this pesticide presented highest toxicity on insects from Vacaria. The ultrastructural analysis showed that abamectin caused malformations in micropyle and in chorion external surface of C. externa eggs. Based in the total effect (E, carbaryl, fenitrothion, and methidathion are harmful to C. externa; trichlorfon is harmless to third-instar larvae, while abamectin and sulphur are harmless and slightly harmful to third-instar larvae from Bento Gonçalves and Vacaria, respectively.

Ecclesiastical Architecture and the Castilian Crisis of the Seventeenth Century: Seville Cathedral and the Church of the Sagrario.

OpenAIRE

d'Arcy, Sing

2014-01-01

When it came time for the critics and historiographers of the late eighteenth and early nineteenth centuries to write the grand narrative of Spanish architecture, the decadence of Habsburg monarchy, economy and society was paralleled to the decline of the noble art itself. The completion of the Escorial in 1584 loomed more like an enormous granite epitaph for Spanish architectural production than the promise of a New Jerusalem. For seventeenth-century architects and theoreticians, like Fray L...

Handbook For Military Justice and Civil Law

Science.gov (United States)

1996-02-01

to supporting her six kids . Noticing that his uniforms are becoming quite frayed (apparently because of the parade of little bodies jumping into...which a substance was packaged; and the fact that an accused was not normally a user. The fact that an accused was addicted to or was a heavy user...Article 510.68 of OPNAVINST 3120.32, Subj: STANDARD ORGANIZATION AND REGULATIONS OF THE U.S. NAVY no longer prohibits the possession of pornography on

Impact on sexual function of surgical treatment in rectal cancer

Directory of Open Access Journals (Sweden)

Pedro Costa

Full Text Available ABSTRACT Introduction The development of new surgical techniques and medical devices, like therapeutical multimodal approaches has allowed for better outcomes on patients with rectal cancer (RCa. Owing to that, an increased awareness and investment towards better outcomes regarding patients’ sexual and urinary function has been recently observed. Aim Evaluate and characterize the sexual dysfunction of patients submitted to surgical treatment for RCa. Materials and Methods An observational retrospective study including all male patients who underwent a surgical treatment for RCa between January 2011 December 2014 (n=43 was performed, complemented with an inquiry questionnaire to every patient about its sexual habits and level of function before and after surgery. Discussion All patients were male, with an average of 64yo. (range 42-83yo.. The surgical procedure was a rectum anterior resection (RAR in 22 patients (56% and an abdominoperineal resection (APR in 19(44%. Sixty three percent described their sexual life as important/very important. Sexual function worsening was observed in 76% (65% with complains on erectile function, and 27% on ejaculation. Fourteen patients (38% didn't resume sexual activity after surgery. Increased age (p=0.007, surgery performed (APR (p=0.03 and the presence of a stoma (p=0.03 were predictors of ED after surgery. A secondary analysis found that the type of surgery (APR (p=0.04, lower third tumor's location (p=0.03 and presence of comorbidities (p=0.013 (namely, smokers and diabetic patients were predictors of de novo ED after surgery. Conclusions This study demonstrated the clear negative impact in sexual function of patients submitted to a surgical treatment for RCa. Since it is a valued feature for patients, it becomes essential to correctly evaluate/identify these cases in order to offer an adequate therapeutical option.

Pacific Canada's Rockfish Conservation Areas: using Ostrom's design principles to assess management effectiveness

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Darienne Lancaster

2015-09-01

Full Text Available International declines in marine biodiversity have lead to the creation of marine protected areas and fishery reserve systems. In Canada, 164 Rockfish Conservation Areas (RCAs were implemented between 2003 and 2007 and now cover 4847.2 km² of ocean. These reserves were created in response to widespread concern from fishers and nongovernmental organizations about inshore rockfish (genus Sebastes population declines. We used the design principles for effective common-pool resource management systems, originally developed by Elinor Ostrom, to assess the social and ecological effectiveness of these conservation areas more than 10 years after their initial implementation. We assessed the relative presence or absence of each design principle within current RCA management. We found that 2 of the 11 design principles were moderately present in the recreational fishery. All other design principles were lacking for the recreational sector. We found that 2 design principles were fully present and 5 were moderately present in the commercial sector. Four design principles were lacking in the commercial sector. Based on this analysis, we highlight 4 main areas for management improvement: (1 create an education and outreach campaign to explain RCA rules, regulations, boundaries, and the need for marine conservation; (2 increase monitoring of users and resources to discourage noncompliance and gather the necessary data to create social buy-in for marine conservation; (3 encourage informal nested governance through stakeholder organizations for education and self-regulation (e.g. fisher to fisher; and (4 most importantly, create a formal, decadal RCA review process to gather stakeholder input and make amendments to regulations and RCA boundaries. This information can be used to inform spatial management systems both in Canada and internationally. This analysis also contributes to a growing literature on effectively scaling up small-scale management techniques

Introduction of an individually optimized protocol for the injection of contrast medium for coronary CT angiography

International Nuclear Information System (INIS)

Seifarth, Harald; Puesken, Michael; Wienbeck, Susanne; Wessling, Johannes; Maintz, David; Heindel, Walter; Juergens, Kai-Uwe; Kalafut, John F.

2009-01-01

The aim of this study was to determine whether individually tailored protocols for the injection of contrast medium (CM) result in higher and more homogeneous vascular attenuation throughout the coronary arteries at coronary CT angiography compared with conventional injection protocols using fixed injection parameters. Of 120 patients included in the study, 80 patients were randomized into two groups. Group 1 received 80 mL of CM at 6 mL/s. For group 2 injection parameters were individually adjusted to patient weight, the duration of CT data acquisition, and attenuation parameters following a test bolus. In the control group (group 3) the volume of CM was adjusted to the duration of CT data acquisition and injected at 5 mL/s. Attenuation was measured in the proximal, middle, and distal right coronary artery (RCA), in the proximal and middle left anterior descending artery (LAD), and in cranial and caudal sections of both ventricles. Patient parameters, scan delay, and scan duration did not differ significantly between the groups. Mean CM volume was 82.5 mL (flow rate 5.1 mL/s) in group 2 and 73.5 mL in group 3. Attenuation in both RCA and LAD was significantly higher for group 2 vs. group 3 (RCA: 414.9(±49.9)-396.1(±52.1) HU vs. 366.0(±64.3)-341.6(±72.5) HU; LAD: 398.9(±48.6)-364.6(±44.6) HU vs. 356.3(±69.5)-323.0(±67.2) HU). For group 1 vs. group 2 only attenuation in the distal RCA differed significantly: 396.1(±52.1) vs. 370.7(±70.5) HU. Individually tailored CM injection protocols yield higher attenuation, especially in the distal segments of the coronary vessels, compared with injection protocols using fixed injection parameters. (orig.)

Performance Characterization and Simulation of Amine-Based Vacuum Swing Sorption Units for Spacesuit Carbon Dioxide and Humidity Control

Science.gov (United States)

Swickrath, Michael J.; Watts, Carly; Anderson, Molly; McMillin, Summer; Broerman, Craig; Colunga, Aaron; Vogel, Matthew

2012-01-01

Controlling carbon dioxide (CO2) and water (H2O) vapor concentrations in a space suit is critical to ensuring an astronauts safety, comfort, and capability to perform extra-vehicular activity (EVA) tasks. Historically, this has been accomplished using lithium hydroxide (LiOH) and metal oxide (MetOx) canisters. Lithium hydroxide is a consumable material that requires priming with water before it becomes effective at removing carbon dioxide. MetOx is regenerable through a power-intensive thermal cycle but is significantly heavier on a volume basis than LiOH. As an alternative, amine-based vacuum swing beds are under aggressive development for EVA applications. The vacuum swing units control atmospheric concentrations of both CO2 and H2O through fully-regenerative process. The current concept, referred to as the rapid cycle amine (RCA), has resulted in numerous laboratory prototypes. Performance of these prototypes have been assessed experimentally and documented in previous reports. To support developmental e orts, a first principles model has also been established for the vacuum swing sorption technology. For the first time in several decades, a major re-design of Portable Life Support System (PLSS) for the extra-vehicular mobility unit (EMU) is underway. NASA at Johnson Space Center built and tested an integrated PLSS test bed of all subsystems under a variety of simulated EVA conditions of which the RCA prototype played a significant role. The efforts documented herein summarize RCA test performance and simulation results for single and variable metabolic rate experiments in an integrated context. In addition, a variety of off-nominal tests were performed to assess the capability of the RCA to function under challenging circumstances. Tests included high water production experiments, degraded vacuum regeneration, and deliberate valve/power failure and recovery.

Area/latency optimized early output asynchronous full adders and relative-timed ripple carry adders.

Science.gov (United States)

Balasubramanian, P; Yamashita, S

2016-01-01

This article presents two area/latency optimized gate level asynchronous full adder designs which correspond to early output logic. The proposed full adders are constructed using the delay-insensitive dual-rail code and adhere to the four-phase return-to-zero handshaking. For an asynchronous ripple carry adder (RCA) constructed using the proposed early output full adders, the relative-timing assumption becomes necessary and the inherent advantages of the relative-timed RCA are: (1) computation with valid inputs, i.e., forward latency is data-dependent, and (2) computation with spacer inputs involves a bare minimum constant reverse latency of just one full adder delay, thus resulting in the optimal cycle time. With respect to different 32-bit RCA implementations, and in comparison with the optimized strong-indication, weak-indication, and early output full adder designs, one of the proposed early output full adders achieves respective reductions in latency by 67.8, 12.3 and 6.1 %, while the other proposed early output full adder achieves corresponding reductions in area by 32.6, 24.6 and 6.9 %, with practically no power penalty. Further, the proposed early output full adders based asynchronous RCAs enable minimum reductions in cycle time by 83.4, 15, and 8.8 % when considering carry-propagation over the entire RCA width of 32-bits, and maximum reductions in cycle time by 97.5, 27.4, and 22.4 % for the consideration of a typical carry chain length of 4 full adder stages, when compared to the least of the cycle time estimates of various strong-indication, weak-indication, and early output asynchronous RCAs of similar size. All the asynchronous full adders and RCAs were realized using standard cells in a semi-custom design fashion based on a 32/28 nm CMOS process technology.

Leak Detection in Heat Exchangers and Underground Pipelines Using Radiotracers. Material for Education and On-The-Job Training for Practitioners of Radiotracer Technology

International Nuclear Information System (INIS)

2009-01-01

The International Atomic Energy Agency plays a major role in facilitating the transfer of radiotracer technology to developing Member States. The use of radiotracer techniques is well established in many Member States; some hundred radiotracer and end user specialists have been trained in radiotracer techniques and their applications; nearly 50 radiotracer laboratories have been working in this field. The training of radiotracer practitioners is vital for the provision of quality services to industry. Leak detection using radiotracer techniques is probably one of the most widespread applications of radiotracers in industrial troubleshooting. Radiotracer techniques are the most competitive for online leak inspection of heat exchangers and buried pipelines. Radiotracers help in early detection of leaks in heat exchangers and underground transporting pipelines, thus saving money, reducing shutdown time, ensuring safe operation and protecting the environment from pollution. The training course series on leak detection in heat exchangers and underground pipelines using radiotracers addresses the needs of the radiotracer groups and their end users. Besides training purposes, this material will assist radiotracer groups in establishing their quality control and accreditation systems. This training course material is based on lecture notes and practical work delivered by many experts in IAEA-supported activities. In particular, the Technical Cooperation Projects implemented under the Regional Cooperative Agreement (RCA) of the IAEA Member States in the Asia and the Pacific Region have been successful in transferring and implementing radiotracer techniques for leak detection to many end users from oil and gas production, oil refineries and the petrochemical industry. The experience obtained in the RCA Region is presented in the training material illustrated with many case studies carried out in several RCA Member States. Lectures and case studies were reviewed by a number

Value and limitations of segmental analysis of stress thallium myocardial imaging for localization of coronary artery disease

International Nuclear Information System (INIS)

Rigo, P.; Bailey, I.K.; Griffith, L.S.C.; Pitt, B.; Borow, R.D.; Wagner, H.N.; Becker, L.C.

1980-01-01

This study was done to determine the value of thallium-201 myocardial scintigraphic imaging (MSI) for identifying disease in the individual coronary arteries. Segmental analysis of rest and stress MSI was performed in 133 patients with ateriographically proved coronary artery disease (CAD). Certain scintigraphic segments were highly specific (97 to 100%) for the three major coronary arteries: anterior wall and septum for the left anterior descending (LAD) coronary artery; the inferior wall for the right coronary artery (RCA); and the proximal lateral wall for the circumflex (LCX) artery. Perfusion defects located in the anterolateral wall in the anterior view were highly specific for proximal disease in the LAD involving the major diagonal branches, but this was not true for septal defects. The apical segments were not specific for any of the three major vessels. Although MSI was abnormal in 89% of these patients with CAD, it was less sensitive for identifying individual vessel disease: 63% for LAD, 50% for RCA, and 21% for LCX disease (narrowings > = 50%). Sensitivity increased with the severity of stenosis, but even for 100% occlusions was only 87% for LAD, 58% for RCA and 38% for LCX. Sensitivity diminished as the number of vessels involved increased: with single-vessel disease, 80% of LAD, 54% of RAC and 33% of LCX lesions were detected, but in patients with triple-vessel disease, only 50% of LAD, 50% of RCA and 16% of LCX lesions were identified. Thus, although segmented analysis of MSI can identify disease in the individual coronary arteries with high specificity, only moderate sensitivity is achieved, reflecting the tendency of MSI to identify only the most severely ischemic area among several that may be present in a heart. Perfusion scintigrams display relative distributions rather than absolute values for myocardial blood flow

Lipid Signaling via Pkh1/2 Regulates Fungal CO2 Sensing through the Kinase Sch9

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Susann Pohlers

2017-01-01

Full Text Available Adaptation to alternating CO2 concentrations is crucial for all organisms. Carbonic anhydrases—metalloenzymes that have been found in all domains of life—enable fixation of scarce CO2 by accelerating its conversion to bicarbonate and ensure maintenance of cellular metabolism. In fungi and other eukaryotes, the carbonic anhydrase Nce103 has been shown to be essential for growth in air (~0.04% CO2. Expression of NCE103 is regulated in response to CO2 availability. In Saccharomyces cerevisiae, NCE103 is activated by the transcription factor ScCst6, and in Candida albicans and Candida glabrata, it is activated by its homologues CaRca1 and CgRca1, respectively. To identify the kinase controlling Cst6/Rca1, we screened an S. cerevisiae kinase/phosphatase mutant library for the ability to regulate NCE103 in a CO2-dependent manner. We identified ScSch9 as a potential ScCst6-specific kinase, as the sch9Δ mutant strain showed deregulated NCE103 expression on the RNA and protein levels. Immunoprecipitation revealed the binding capabilities of both proteins, and detection of ScCst6 phosphorylation by ScSch9 in vitro confirmed Sch9 as the Cst6 kinase. We could show that CO2-dependent activation of Sch9, which is part of a kinase cascade, is mediated by lipid/Pkh1/2 signaling but not TORC1. Finally, we tested conservation of the identified regulatory cascade in the pathogenic yeast species C. albicans and C. glabrata. Deletion of SCH9 homologues of both species impaired CO2-dependent regulation of NCE103 expression, which indicates a conservation of the CO2 adaptation mechanism among yeasts. Thus, Sch9 is a Cst6/Rca1 kinase that links CO2 adaptation to lipid signaling via Pkh1/2 in fungi.

Genesis Solar Wind Collector Cleaning Assessment: Update on 60336 Sample Case Study

Science.gov (United States)

Goreva, Y. S.; Allums, K. K.; Gonzalez, C. P.; Jurewicz, A. J.; Burnett, D. S.; Allton, J. H.; Kuhlman, K. R.; Woolum, D.

2015-01-01

To maximize the scientific return of Genesis Solar Wind return mission it is necessary to characterize and remove a crash-derived particle and thin film surface contamination. A small subset of Genesis mission collector fragments are being subjected to extensive study via various techniques. Here we present an update on the sample 60336, a Czochralski silicon (Si-CZ) based wafer from the bulk array (B/C). This sample has undergone multiple cleaning steps (see the table below): UPW spin wash, aggressive chemical cleanings (including aqua regia, hot xylene and RCA1), as well as optical and chemical (EDS, ToF-SIMS) imaging. Contamination appeared on the surface of 60336 after the initial 2007 UPW cleaning. Aqua regia and hot xylene treatment (8/13/2013) did little to remove contaminants. The sample was UPW cleaned for the third time and imaged (9/16/13). The UPW removed the dark stains that were visible on the sample. However, some features, like "the Flounder" (a large, 100 micron feature in Fig. 1b) appeared largely intact, resisting all previous cleaning efforts. These features were likely from mobilized adhesive, derived from the Post-It notes used to stabilize samples for transport from Utah after the hard landing. To remove this contamination, an RCA step 1 organic cleaning (RCA1) was employed. Although we are still uncertain on the nature of the Flounder and why it is resistant to UPW and aqua regia/hot xylene treatment, we have found RCA1 to be suitable for its removal. It is likely that the glue from sticky pads used during collector recovery may have been a source for resistant organic contamination [9]; however [8] shows that UPW reaction with crash-derived organic contamination does not make particle removal more difficult.

DAYA SAING KAKAO INDONESIA DI PASAR INTERNASIONAL

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Anggita Tresliyana

2015-07-01

Full Text Available Cocoa is one of the major Indonesian agricultural export products. Cocoa international market has great potential regarding world’s consumption growth, therefore Indonesia is expected to take advantage on existing opportunities. The aims of this study were to analyze the competitiveness of Indonesian cocoa beans and processed cocoa trade in the international market as well as the level of competition between cocoa exporting countries. By using Revealed Comparative Advantage (RCA and Spearman Rank Correlation, it showed that Indonesia had a comparative advantage as an cocoa exporter on the international market, the highest for cocoa beans and the lowest for cocoa paste; Indonesia also had a significant correlation to exporting countries in cocoa beans’ market (Ghana and cocoa paste’s market (Netherlands and Malaysia, the correlation suggests that there were high correlation between Indonesia and the exporting country in competing for market share.Keywords: cocoa, comparative advantage, international trade, competitiveness, market share, RCA ABSTRAKKakao merupakan salah satu komoditas pertanian unggulan ekspor Indonesia.  Pasar kakao memiliki potensi yang besar dilihat dari peningkatan konsumsi dunia, sehingga Indonesia diharapkan dapat memanfaatkan peluang yang ada.  Tujuan penelitian ini adalah menganalisis daya saing perdagangan biji kakao dan kakao olahan Indonesia di pasar internasional serta hubungan daya saing antar negara eksportir kakao. Dengan menggunakan Reavealed Comparative Advantage (RCA, dan Korelasi Rank Spearman, hasil analisis menunjukkan bahwa Indonesia memiliki keunggulan komparatif sebagai eksportir biji kakao dan kakao olahan di pasar internasional, tertinggi untuk biji kakao dan terendah untuk kakao pasta;  Indonesia juga memiliki korelasi yang signifikan di beberapa negara untuk pasar biji kakao (Ghana dan kakao pasta (Belanda dan Malaysia, korelasi tersebut menunjukkan bahwa terdapat hubungan daya saing yang cukup

Application of the newly developed Japanese adenosine normal database for adenosine stress myocardial scintigraphy.

Science.gov (United States)

Harata, Shingo; Isobe, Satoshi; Morishima, Itsuro; Suzuki, Susumu; Tsuboi, Hideyuki; Sone, Takahito; Ishii, Hideki; Murohara, Toyoaki

2015-10-01

The currently available Japanese normal database (NDB) in stress myocardial perfusion scintigraphy recommended by the Japanese Society of Nuclear Medicine (JSNM-NDB) is created based on the data from exercise tests. The newly developed adenosine normal database (ADS-NDB) remains to be validated for patients undergoing adenosine stress test. We tested whether the diagnostic accuracy of adenosine stress test is improved by the use of ADS-NDB (Kanazawa University). Of 233 consecutive patients undergoing (99m)Tc-MIBI adenosine stress test, 112 patients were tested. The stress/rest myocardial (99m)Tc-MIBI single-photon emission computed tomography (SPECT) images were analyzed by AutoQUANT 7.2 with both ADS-NDB and JSNM-NDB. The summed stress score (SSS) and summed difference score (SDS) were calculated. The agreements of the post-stress defect severity between ADS-NDB and JSNM-NDB were assessed using a weighted kappa statistic. In all patients, mean SSSs of all, right coronary artery (RCA), left anterior descending (LAD), and left circumflex (LCx) territories were significantly lower with ADS-NDB than those with JSNM-NDB. Mean SDSs in all, RCA, and LAD territories were significantly lower with ADS-NDB than those with JSNM-NDB. In 28 patients with significant coronary stenosis, the mean SSS in the RCA territory was significantly lower with ADS-NDB than that with JSNM-NDB. In 84 patients without ischemia, both mean SSSs and SDSs in all, RCA, LAD, and LCx territories were significantly lower with ADS-NDB than those with JSNM-NDB. Weighted kappa values of all patients, patients with significant stenosis, and patients without ischemia were 0.89, 0.83, and 0.92, respectively. Differences were observed between results from ADS-NDB and JSNM-NDB. The diagnostic accuracy of adenosine stress myocardial perfusion scintigraphy may be improved by reducing false-positive results.

Giuseppe Antonino Biondo e la fondazione dell’International Recording

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Paolo Biondo

2015-08-01

Full Text Available Giuseppe Antonino Biondo (1899-1988, a US citizen of Italian origins, was one of the most important entrepreneurs in the fields of discography and film sound post-production in Italy. A leading figure at American RCA, G.A. Biondo moved to Rome during the 1950s, where he founded RCA Italiana and, a few years later, International Recording, which became one of the main post-production companies in Italy until the 2000s. These operations deeply impacted on the technological and industrial setting of Italian cinema. In this essay we recall G.A. Biondo’s early years in the US and we deal with the chain of events that led to the birth of International Recording.

The mitochondrial inner membrane AAA metalloprotease family in metazoans.

Science.gov (United States)

Juhola, M K; Shah, Z H; Grivell, L A; Jacobs, H T

2000-09-15

Three metalloproteases belonging to the AAA superfamily (Yme1p, Afg3p and Rca1p) are involved in protein turnover and respiratory chain complex assembly in the yeast inner mitochondrial membrane. Analysis of the completed genome sequences of Caenorhabditis elegans and Drosophila melanogaster indicates that this gene family typically comprises 3-4 members in metazoans. Phylogenetic analysis reveals three main branches represented, respectively, by Saccharomyces cerevisiae YME1, human SPG7 (paraplegin) and S. cerevisiae AFG3 and RCA1. mt-AAA metalloproteases are weak candidates for several previously studied Drosophila mutants. A full elucidation of the cellular and physiological roles of mt-AAA metalloproteases in metazoans will require the creation of targeted mutations.

Uma padre na aldeia global : nova evangelização e novas tecnologias de informação e comunicação

OpenAIRE

Aguiar, Américo Manuel Alves

2012-01-01

Nesta dissertação, revemos os últimos cem anos de pronunciamentos dos sucessores de Pedro, do Papa Leão XIII, ao Papa Bento XVI, atestando a atenção e interesse com que a igreja católica sempre olhou para as potencialidades oferecidas pelas novas tecnologias de informação e de comunicação. Olhamos de um ponto de vista comunicacional para a urgência da Nova Evangelização pronunciada pelo Papa João Paulo II, dando continuidade ao já expresso pelo Papa Paulo VI e pelo próprio II ...

Seguridad y protección de información de la bahía interior de puno del lago Titicaca

OpenAIRE

Canqui Flores, Bernabé

2001-01-01

El presente estudio se ha ejecutado en la provincia de Puno, el conocimiento de aplicaciones informáticas en el campo de la Biología, de información cualitativa y cuantitativa, se realiza para la creación de software aplicativo, utilizando lenguajes de alto nivel, para ofrecer seguridad, conftabilidad y protección de información de la Bahía Interior de Puno del Lago Titicaca. Esta investigación se desarrolló con información de Bentos en tres épocas climáticas (Junio-Julio, Agosto-Setiembre y ...

Fosforitos do Grupo Bambuí na região de Campos Belos (GO)/ Arraias (TO), na borda oeste do Cráton São Francisco

OpenAIRE

Monteiro, Cimara Francisca

2009-01-01

Os depósitos de fosfato sedimentar da região de Campos Belos (GO) e Arraias (TO) compreendem ate o momento três depósitos de volume reduzido, mas com teores elevados, superiores a 24% P2O5, denominados: São Bento, Coite 1 e Coite 2. Os fosforitos e siltitos fosfatados encontrados na regiao estao inseridos na porcao basal da Formação Sete Lagoas, pertencente ao Grupo Bambui, de idade Neoproterozoica. O Grupo Bambui integra a porção oriental da Faixa de Dobramentos Brasília e tambem compõe ampl...

GEOCHEMISTRY AND ISOTOPE HYDROLOGY OF AN URBAN AQUIFER, SUBTROPICAL AFRICA, CENTRAL AFRICAN REPUBLIC

International Nuclear Information System (INIS)

HUSSEIN, M.F.; ISLAM, A.; GAMAL, S.; GAETAN, M.; DJEBEBE, C.

2008-01-01

Africa south of the Great Sahara has abundant water resources, however, its aquifers are seldom studied and/or inadequately managed. This study presents a geochemical and isotope hydrology study on the aquifer of Bangui city, the capital of the Central African Republic (RCA), on the northern borders of Congo with RCA.The obtained chemical data demonstrated the role of biogenic CO 2 gas, solid phases and cation exchange in the hydrochemistry of the studied groundwater. The conjunctive use of the major dissolved constituents and the isotope contents ( 18 O and 2 H) showed that the alteration of primary silicates and the dissolution of carbonates are the predominant processes that locally define the zones of dilute and relatively charged groundwater, respectively.The isotope data illustrated that evaporation is non-significantly contributing to the water loss from the aquifer, while transpiration (process that goes almost without isotopic fractionation) is prevailing in the water balance of the local drainage basin, with a significant fraction of the transpired vapour being recycled. An isotopic i nverse continental effect(eastward from Cameron to RCA) is explained through differences in air temperatures, amount and altitude of precipitation rather than by inverse movement of humid air masses westward in Central Africa

A new cleaning process for the metallic contaminants on a post-CMP wafer's surface

International Nuclear Information System (INIS)

Gao Baohong; Liu Yuling; Wang Chenwei; Wang Shengli; Zhou Qiang; Tan Baimei; Zhu Yadong

2010-01-01

This paper presents a new cleaning process using boron-doped diamond (BDD) film anode electrochemical oxidation for metallic contaminants on polished silicon wafer surfaces. The BDD film anode electrochemical oxidation can efficiently prepare pyrophosphate peroxide, pyrophosphate peroxide can oxidize organic contaminants, and pyrophosphate peroxide is deoxidized into pyrophosphate. Pyrophosphate, a good complexing agent, can form a metal complex, which is a structure consisting of a copper ion, bonded to a surrounding array of two pyrophosphate anions. Three polished wafers were immersed in the 0.01 mol/L CuSO 4 solution for 2 h in order to make comparative experiments. The first one was cleaned by pyrophosphate peroxide, the second by RCA (Radio Corporation of America) cleaning, and the third by deionized (DI) water. The XPS measurement result shows that the metallic contaminants on wafers cleaned by the RCA method and by pyrophosphate peroxide is less than the XPS detection limits of 1 ppm. And the wafer's surface cleaned by pyrophosphate peroxide is more efficient in removing organic carbon residues than RCA cleaning. Therefore, BDD film anode electrochemical oxidation can be used for microelectronics cleaning, and it can effectively remove organic contaminants and metallic contaminants in one step. It also achieves energy saving and environmental protection. (semiconductor technology)

Assessment of climate change impact on water resources in the Pungwe river basin

Energy Technology Data Exchange (ETDEWEB)

Andersson, Lotta; Samuelsson, Patrick; Kjellstroem, Erik (Swedish Meteorological and Hydrological Inst., Norrkoeping (Sweden)), e-mail: lotta.andersson@smhi.se

2011-01-15

The Rossby Centre Regional Climate Model (RCA3) and the hydrological model HBV were linked to assess climate change impacts on water resources in the Pungwe basin until 2050. RCA3 was capable of simulating the most important aspects of the climate for a control period at the regional scale. At the subbasin scale, additional scaling was needed. Three climate change experiments using ECHAM4-A2, B2 and CCSM3-B2 as input to RCA3 were carried out. According to the simulations annual rainfall in 2050 would be reduced by approximately 10% with increasing interannual variability of rainfall and dry season river flow and later onset of the rainy season. The ECHAM4-A2 driven experiment did also indicate a slight increase of high flows. If the results indeed reflect the future, they will worsen the already critical situation for water resources, regarding both floods and droughts. Uncertainties, however in the downscaled scenarios make it difficult to prioritize adaptation options. This calls for inclusion of more climate change experiments, in an ensemble of climate scenarios possibly by using a combination of dynamical and statistical downscaling of general circulation models, as well as extending the simulations to 2100 to further ensure robustness of the signal

Applications of research results from NPAR service water system studies

International Nuclear Information System (INIS)

Jarrell, D.B.; Stratton, R.C.

1991-01-01

Under the Nuclear Plant Aging Research (NPAR) program, the Nuclear Regulatory Commission (NRC) has invested considerable resources in understanding the mechanisms, mitigating the damage, and managing the results of nuclear power plant aging degradation. Many direct benefits have resulted from this program in terms of improved plant safety through upgraded regulatory guidance. The 'Service Water System (SWS) Aging Degradation Assessment' (NUREG/CR-5379), produced by the Pacific Northwest Laboratory (PNL), contributed to this program. Two other benefits have resulted from the NPAR SWS task: (1) a contribution to the content of Generic Letter 89-13 (nuclear plant SWS performance requirements) and (2) the development of a systematic and complete root-cause analysis (RCA) methodology for use in the solution of SWS as well as other system component failures. Less recognized, but also of significance, are the spin-off initiatives from the NRC's NPAR program investigations. One such spin-off resulting specifically from the NRC-sponsored SWS research is the continuing development of the RCA methodology to facilitate the computerized integration of the following: (1) component condition monitoring; (2) fault diagnostics; and (3) failure root cause analysis. The Decision Support system for Operations and Maintenance project being developed at PNL is implementing the NPAR-developed RCA methodology utilizing an artificial intelligence approach

Thirty Years Researches on Development for Sustainable Concrete Technology

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Sim Jongsung

2017-01-01

Full Text Available The enormous amount of concrete production has a serious impact on energy, resources, environment and ecosystem. Therefore, the issue of development of sustainable concrete technology with little impact on the environment is becoming a major issue. In this paper, researches related with sustainable development of concrete are presented in last three decades. FRP has high corrosion resistance and lightweight, thus it can be potential solution for sustainable development of concrete structures as strengthening material or reinforcement instead of steel. Researches and techniques are presented on performance of concrete beam with FRP rebar and enhancing performance of existing concrete structure using FRP strengthening methods. The application of recycled concrete aggregate (RCA has sometimes been limited in the practice and remained in the low-valued purposes only such as road base materials. In past 10 years, a great improvement in the recycling technique to produce RCA of which quality is close to natural aggregate, hence the applicability and evaluation of RCA are presented in this paper. This paper includes experimental studies for application of waste glass which could decrease CO2 emission from cement producing. The achievements of these studies are presented in this paper to contribute for sustainable development of concrete infrastructures.

Differing lectin-binding patterns of malignant melanoma and nevocellular and Spitz nevi.

Science.gov (United States)

Kohchiyama, A; Oka, D; Ueki, H

1987-01-01

The lectin-binding patterns of primary malignant melanoma, nevocellular nevus, and Spitz nevus were studied on formalin-fixed, paraffin-embedded sections using a series of biotinylated lectins--concanavalin A (ConA), Ricinus communis agglutinin-1 (RCA1), dolichos biflorus agglutinin (DBA), soybean agglutinin (SBA), maclura pomifera agglutinin (MPA), peanut agglutinin (PNA), wheat germ agglutinin (WGA), and Ulex europeus agglutinin-1(UEA1)--and employing the avidin-biotin-peroxidase complex method. In nevocellular and Spitz nevi, all of the nevus cells were positively stained with ConA and RCA1. No positive staining was observed, however, with the other lectins and no change in binding patterns occurred following neuraminidase pretreatment. In malignant melanoma, all of the melanoma cells were positively stained with ConA and RCA1, and some were also stained with MPA, PNA, and WGA. In addition, DBA, SBA, MPA, PNA, and WGA labeled all of the melanoma cells after neuraminidase pretreatment. No positive staining was observed with UEA1 despite neuraminidase pretreatment. The present results showed that malignant melanoma and nevocellular and Spitz nevi have different lectin-binding patterns and different responses to neuraminidase pretreatment. We, therefore, believe that the lectin staining on paraffin-embedded sections can be a useful probe for the differentiation of these diseases.

Validity of Race, Ethnicity, and National Origin in Population-based Cancer Registries and Rapid Case Ascertainment Enhanced With a Spanish Surname List.

Science.gov (United States)

Clarke, Lisa C; Rull, Rudolph P; Ayanian, John Z; Boer, Robert; Deapen, Dennis; West, Dee W; Kahn, Katherine L

2016-01-01

Accurate information regarding race, ethnicity, and national origins is critical for identifying disparities in the cancer burden. To examine the use of a Spanish surname list to improve the quality of race-related information obtained from rapid case ascertainment (RCA) and to estimate the accuracy of race-related information obtained from cancer registry records collected by routine reporting. Self-reported survey responses of 3954 participants from California enrolled in the Cancer Care Outcomes Research and Surveillance Consortium. Sensitivity, specificity, positive predictive value, and percent agreement. We used logistic regression to identify predictors of underreporting and overreporting of a race/ethnicity. Use of the Spanish surname list increased the sensitivity of RCA for Latino ethnicity from 37% to 83%. Sensitivity for cancer registry records collected by routine reporting was ≥95% for whites, blacks, and Asians, and specificity was high for all groups (86%-100%). However, patterns of misclassification by race/ethnicity were found that could lead to biased cancer statistics for specific race/ethnicities. Discordance between self-reported and registry-reported race/ethnicity was more likely for women, Latinos, and Asians. Methods to improve race and ethnicity data, such as using Spanish surnames in RCA and instituting data collection guidelines for hospitals, are needed to ensure minorities are accurately represented in clinical and epidemiological research.

COMPETITIVENESS OF INDONESIAN TEA IN INTERNATIONAL MARKET

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Jauhar Samudera

2017-01-01

Full Text Available Since 2000, Indonesian tea has experienced a lot of problems such as land use change of plantation, lower selling prices, and low productivity. The objectives of this study are to analyze the competitiveness of tea in Indonesia and formulate priority improvements that can support the increasing competitiveness of Indonesian tea. The methods used to analyze the competitiveness were the Revealed Comparative Advantage (RCA and the Export Product Dynamics (EPD, and to formulate strategies to increase competitiveness, Importance Performance Analysis (IPA was applied. Based on RCA, the types of Indonesian tea which have strong competitiveness are HS 090 210 and HS 090240. The EPD analysis showed that only tea of HS 090210 is in the rising star position, while the HS 090220, HS 090230 and HS090240 tea types are on the retreat position. Based on IPA, sub-determinants which are priority to improve are in quadrant A (under act consisting of five sub-factors, namely the availability of human resources with the capbility of production management, marketing and possess an entrepreneurial spirit; availability and ease of access to capital; strengthening of the structure of Indonesian tea agribusiness; the government policies in improving domestic demand conditions and in encouraging the development of tea processing industry.Keywords: competitiveness, tea, RCA, EPD, IPA

Flexural Behavior of Corroded Reinforced Recycled Aggregate Concrete Beams

Directory of Open Access Journals (Sweden)

Taoping Ye

2018-01-01

Full Text Available Recycling concrete not only reduces the use of virgin aggregate but also decreases the pressure on landfills. As a result, recycled coarse aggregate (RCA is extensively recommended for new construction projects. However, the flexural behavior of corroded reinforced recycled aggregate concrete (RAC beams is uncertain. The experimental research presented in this paper was performed to investigate the flexural behavior of corroded reinforced RAC beams compared to that of corroded reinforced natural aggregate concrete (NAC beams and consequently explore the possibility of using RAC beams in corrosive environments. Four different percentages of RCA in total mass of coarse aggregate in concrete mixtures (0%, 33%, 66%, and 100% and two different concrete strengths (C30, C60 were the governing parameters. The electrochemical method was adopted to accelerate steel corrosion. Full-scale tests were performed on eight simply supported beams until the failure load was reached. Comparison of load-deflection behavior, crack patterns, failure modes, ductility, and ultimate flexural capacity of corroded reinforced NAC and RAC beams was made based on the experimental results obtained. The comparison results show that the flexural behavior of corroded reinforced RAC beams with an appropriate percentage of RCA is satisfactory compared to the behavior of NAC beams.

An integrated approach to the analysis of causes of crime/public disorder—A case study for the “Tlahuac” incident

International Nuclear Information System (INIS)

Ferjencik, Milos

2012-01-01

The article by Santos-Reyes et al. (2009) on the cause analysis of the “Tlahuac” incident demonstrates the applicability of the MORT method to a problem concerning crime/public disorder. Although the idea to expand the use of MORT to the complete root cause analysis (RCA) using the predefined tree MORT is natural, at least three deficiencies are expected: (1) limited applicability to causal factors identified in the incident, (2) insufficient depth of cause analysis, and (3) insufficient coverage of safety culture. Therefore, an innovative integrated approach is recommended that extends the abilities of the RCA. The outline of reanalysis illustrates the application of the integrated approach and demonstrates its important features: (i) identification of causal factor processes; (ii) the presence of two cause levels under the root cause level; and (iii) the application of a STAMP-type technique to the causal factors and cause levels where the RCA is not applicable. The integrated approach is able to identify a wider and deeper set of causes than root cause analysis. It is suitable for the cause analysis of causal factors occurring in unorganized and uncontrolled processes, which are considered to be the special features typical for incidents of crime or public disorder.

Morphology-Variable Aggregates Prepared from Cholesterol-Containing Amphiphilic Glycopolymers: Their Protein Recognition/Adsorption and Drug Delivery Applications

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Zhao Wang

2018-02-01

Full Text Available In this study, a series of diblock glycopolymers, poly(6-O-methacryloyl-d-galactopyranose-b-poly(6-cholesteryloxyhexyl methacrylate (PMAgala-b-PMAChols, with cholesterol/galactose grafts were prepared through a sequential reversible addition-fragmentation chain transfer (RAFT polymerization and deprotection process. The glycopolymers could self-assemble into aggregates with various morphologies depending on cholesterol/galactose-containing block weight ratios, as determined by transmission electronic microscopy (TEM and dynamic laser light scattering (DLS. In addition, the lectin (Ricinus communis agglutinin II, RCA120 recognition and bovine serum albumin (BSA adsorption of the PMAgala-b-PMAChol aggregates were evaluated. The SK-Hep-1 tumor cell inhibition properties of the PMAgala-b-PMAChol/doxorubicin (DOX complex aggregates were further examined in vitro. Results indicate that the PMAgala-b-PMAChol aggregates with various morphologies showed different interaction/recognition features with RCA120 and BSA. Spherical aggregates (d ≈ 92 nm possessed the highest RCA120 recognition ability and lowest BSA protein adsorption. In addition, the DOX-loaded spherical complex aggregates exhibited a better tumor cell inhibition property than those of nanofibrous complex aggregates. The morphology-variable aggregates derived from the amphiphilic glycopolymers may serve as multifunctional biomaterials with biomolecular recognition and drug delivery features.

Increasing the reliability of the fluid/crystallized difference score from the Kaufman Adolescent and Adult Intelligence Test with reliable component analysis.

Science.gov (United States)

Caruso, J C

2001-06-01

The unreliability of difference scores is a well documented phenomenon in the social sciences and has led researchers and practitioners to interpret differences cautiously, if at all. In the case of the Kaufman Adult and Adolescent Intelligence Test (KAIT), the unreliability of the difference between the Fluid IQ and the Crystallized IQ is due to the high correlation between the two scales. The consequences of the lack of precision with which differences are identified are wide confidence intervals and unpowerful significance tests (i.e., large differences are required to be declared statistically significant). Reliable component analysis (RCA) was performed on the subtests of the KAIT in order to address these problems. RCA is a new data reduction technique that results in uncorrelated component scores with maximum proportions of reliable variance. Results indicate that the scores defined by RCA have discriminant and convergent validity (with respect to the equally weighted scores) and that differences between the scores, derived from a single testing session, were more reliable than differences derived from equal weighting for each age group (11-14 years, 15-34 years, 35-85+ years). This reliability advantage results in narrower confidence intervals around difference scores and smaller differences required for statistical significance.

Ecología química en el bentos antártico

OpenAIRE

Ballesteros, Manuel (Ballesteros Vázquez); Núñez Pons, Laura; Vázquez, J.; Cristobo, F.J.; Taboada Moreno, Sergio; Figuerola Balañá, Blanca; Ávila Escartín, Conxita

2011-01-01

El estudio de las interacciones entre los organismos mediadas por sustancias químicas, lo que se denomina ecología química, nos da información sobre la biología de las especies implicadas, el funcionamiento de la comunidad en que viven y nos puede proporcionar además el conocimiento de nuevas sustancias que pueden ser útiles para el ser humano. En el marco de nuestros estudios sobre la ecología química de los invertebrados antárticos, en el proyecto ECOQUIM (2003-2006) se recolectaron numeros...

Radiocesium retention in the aquatic, terrestrial and urban environment: a quantitative and unifying analysis

International Nuclear Information System (INIS)

Preter, P. de

1990-01-01

The frayed edges of 10 A phyllosilicates (micaceous minerals), responsible for the highly selective sorption of poorly hydrated alkali cations (Cs, Rb, K) in NH$/sb4$, are quantitatively characterized by masking the planar sites with silver-thiourea. Both the capacity of the frayed edge sites (FES) and the Cs-to-K selectivity coefficient of these sites can be measured. The loading dependence of the Cs-to-K selectivity coefficient in the FES of 4 micaceous minerals demonstrates a pronounced degree of heterogeneity. Only a small fraction of the FES ($<$10%) exhibits extremely high Cs preference. For studying complex mineralogical systems (soils, sediments, rocks and ceramics) a new parameter is introduced: the ''radiocesium interception potential'', defined as the product of FES capacity and the Cs-to-K (or NH$/sb4$) selectivity coefficient in the FES at ''zero'' Cs loading. This parameter is a powerful tool in describing and predicting the highly selective sorption processes in the FES. Under freshwater conditions the radiocesium distribution coefficient can be quantitatively predicted by considering a competition with K and NH$/sb4$ in the FES. In a marine environment Na, and to a lesser extent Ca and Mg, also have to be taken into account. Finally, evidences for a redistribution process are given: sorbed Cs ions diffuse to the interlayers of the clay particles. This phenomenon explains the increasing ''fixation'' of radiocesium with time

Kinetics and reversibility of radiocaesium solid/liquid partitioning in sediments

International Nuclear Information System (INIS)

Comans, R.N.J.

1998-01-01

The kinetics and reversibility of radiocaesium solid/liquid partitioning in sediments have been reviewed and interpreted in terms of a mechanistic framework. This framework is based on the premise that radiocaesium is almost exclusively and highly-selectively bound to the frayed particle edges of illitic clay minerals in the sediments. Several processes with distinctly different rates can be distinguished in radiocaesium sorption to sediments. 2- and 3-box kinetic models can describe both the overall solid/liquid partitioning in sediments and the reversible (exchangeable) and irreversible (nonexchangeable or 'fixed') fractions of radiocaesium in sediments over time scales relevant for natural aquatic systems. The obtained rate parameters indicate that reversible partitioning of radiocaesium dominates over the first few days following a contamination event, whereas irreversible kinetics becomes important over time scales of weeks to months. The slow process, which reduces the exchangeability of sediment-bound radiocaesium over time, is believed to result from a migration of radiocaesium from exchangeable sites on the frayed edges of illite towards less-exchangeable interlayer sites. Long-term extraction of radiocaesium from historically contaminated sediments has given evidence for a reverse (remobilization) process with a half-life of the order of tens of years. These findings suggest that the long-term exchangeability of radiocaesium in sediments may be higher than the few % which is generally assumed. (orig.)

Ricinus communis agglutinin-mediated agglutination and fusion of glycolipid-containing phospholipid vesicles: effect of carbohydrate head group size, calcium ions, and spermine.

Science.gov (United States)

Hoekstra, D; Düzgüneş, N

1986-03-25

The glycolipids galactosylcerebroside (GalCer), lactosylceramide (LacCer), and trihexosylceramide (Gb3) were inserted into phospholipid vesicles, consisting of phosphatidylethanolamine and phosphatidic acid. The extent to which their carbohydrate head groups protruded beyond the vesicle surface and their interference with membrane approach were examined by determining vesicle susceptibility toward type I Ricinus communis agglutinin (RCA1) induced agglutination and Ca2+- and spermine-induced aggregation and fusion either in the presence or in the absence of the lectin. The initial agglutination rates increased in the order GalCer much less than LacCer less than Gb3, while a reversed order was obtained for Ca2+- and spermine-induced aggregation and fusion, indicating an enhanced steric interference on close approach of bilayers with increasing head group size. The lectin-mediated agglutination rates for LacCer- and Gb3-containing vesicles increased by an order of magnitude when Ca2+ was also included in the medium, at a concentration that did not induce aggregation per se. Charge neutralization could not account for this observation as the polyvalent cation spermine did not display this synergistic effect with RCA1. Addition of Ca2+ to preagglutinated vesicles substantially reduced the threshold cation concentration for fusion (micromolar vs. millimolar). Quantitatively, this concentration decreased with decreasing carbohydrate head group size, indicating that the head group protrusion determined the interbilayer distance within the vesicle aggregate. The distinct behavior of Ca2+ vs. spermine on RCA1-induced agglutination on the one hand and fusion on the other indicated that Ca2+ regulates the steric orientation of the carbohydrate head group, which appears to be related to its ability to dehydrate the bilayer. As a result, lectin agglutinability becomes enhanced while fusion will be interrupted as the interbilayer distance increases, the threshold head group size

¿La imitación o el arte de copiar?

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José Luis García

2015-01-01

Full Text Available A lo largo de los siglos y en diferentes manifestaciones artísticas (pintura, literatura, música, la imitación o el arte de copiar (plagio es una palabra muy dura ha sido frecuente en los maestros y en los aprendices unos por "ley de procreación" (Fray Luis de León, otros por aprendizaje y otros por suplir sus carencias y lograr la fama. El texto expone algunos de estos casos e ingeniosas opiniones al respecto

Lipid Signaling via Pkh1/2 Regulates Fungal CO2 Sensing through the Kinase Sch9.

Science.gov (United States)

Pohlers, Susann; Martin, Ronny; Krüger, Thomas; Hellwig, Daniela; Hänel, Frank; Kniemeyer, Olaf; Saluz, Hans Peter; Van Dijck, Patrick; Ernst, Joachim F; Brakhage, Axel; Mühlschlegel, Fritz A; Kurzai, Oliver

2017-01-31

Adaptation to alternating CO 2 concentrations is crucial for all organisms. Carbonic anhydrases-metalloenzymes that have been found in all domains of life-enable fixation of scarce CO 2 by accelerating its conversion to bicarbonate and ensure maintenance of cellular metabolism. In fungi and other eukaryotes, the carbonic anhydrase Nce103 has been shown to be essential for growth in air (~0.04% CO 2 ). Expression of NCE103 is regulated in response to CO 2 availability. In Saccharomyces cerevisiae, NCE103 is activated by the transcription factor ScCst6, and in Candida albicans and Candida glabrata, it is activated by its homologues CaRca1 and CgRca1, respectively. To identify the kinase controlling Cst6/Rca1, we screened an S. cerevisiae kinase/phosphatase mutant library for the ability to regulate NCE103 in a CO 2 -dependent manner. We identified ScSch9 as a potential ScCst6-specific kinase, as the sch9Δ mutant strain showed deregulated NCE103 expression on the RNA and protein levels. Immunoprecipitation revealed the binding capabilities of both proteins, and detection of ScCst6 phosphorylation by ScSch9 in vitro confirmed Sch9 as the Cst6 kinase. We could show that CO 2 -dependent activation of Sch9, which is part of a kinase cascade, is mediated by lipid/Pkh1/2 signaling but not TORC1. Finally, we tested conservation of the identified regulatory cascade in the pathogenic yeast species C. albicans and C. glabrata Deletion of SCH9 homologues of both species impaired CO 2 -dependent regulation of NCE103 expression, which indicates a conservation of the CO 2 adaptation mechanism among yeasts. Thus, Sch9 is a Cst6/Rca1 kinase that links CO 2 adaptation to lipid signaling via Pkh1/2 in fungi. All living organisms have to cope with alternating CO 2 concentrations as CO 2 levels range from very low in the atmosphere (0.04%) to high (5% and more) in other niches, including the human body. In fungi, CO 2 is sensed via two pathways. The first regulates virulence in

Integration of prognostic aerosol-cloud interactions in a chemistry transport model coupled offline to a regional climate model

Science.gov (United States)

Thomas, M. A.; Kahnert, M.; Andersson, C.; Kokkola, H.; Hansson, U.; Jones, C.; Langner, J.; Devasthale, A.

2015-06-01

To reduce uncertainties and hence to obtain a better estimate of aerosol (direct and indirect) radiative forcing, next generation climate models aim for a tighter coupling between chemistry transport models and regional climate models and a better representation of aerosol-cloud interactions. In this study, this coupling is done by first forcing the Rossby Center regional climate model (RCA4) with ERA-Interim lateral boundaries and sea surface temperature (SST) using the standard cloud droplet number concentration (CDNC) formulation (hereafter, referred to as the "stand-alone RCA4 version" or "CTRL" simulation). In the stand-alone RCA4 version, CDNCs are constants distinguishing only between land and ocean surface. The meteorology from this simulation is then used to drive the chemistry transport model, Multiple-scale Atmospheric Transport and Chemistry (MATCH), which is coupled online with the aerosol dynamics model, Sectional Aerosol module for Large Scale Applications (SALSA). CDNC fields obtained from MATCH-SALSA are then fed back into a new RCA4 simulation. In this new simulation (referred to as "MOD" simulation), all parameters remain the same as in the first run except for the CDNCs provided by MATCH-SALSA. Simulations are carried out with this model setup for the period 2005-2012 over Europe, and the differences in cloud microphysical properties and radiative fluxes as a result of local CDNC changes and possible model responses are analysed. Our study shows substantial improvements in cloud microphysical properties with the input of the MATCH-SALSA derived 3-D CDNCs compared to the stand-alone RCA4 version. This model setup improves the spatial, seasonal and vertical distribution of CDNCs with a higher concentration observed over central Europe during boreal summer (JJA) and over eastern Europe and Russia during winter (DJF). Realistic cloud droplet radii (CD radii) values have been simulated with the maxima reaching 13 μm, whereas in the stand

The influence of body mass index and gender on coronary arterial attenuation with fixed iodine load per body weight at dual-source CT coronary angiography

International Nuclear Information System (INIS)

Zhu, Xiaomei; Zhu, Yinsu; Xu, Hai; Tang, Lijun; Xu, Yi

2012-01-01

Background. Most of current coronary CT angiography protocols are not adapted to body weight (BW) or cardiac output and no literature about influence of gender on coronary attenuation are reported with administration of a fixed iodine load per BW. Purpose. To determine the influence of body mass index (BMI) and gender on coronary arterial attenuation if contrast material dose is linearly adjusted to a patient's BW at dual-source CT coronary angiography (DSCT-CA). Material and Methods. A total of 207 consecutive patients (mean age 60.6 years) undergoing DSCT-CA were included. Contrast material (370 mg I/mL) dose calculation was randomly categorized into two groups (Group1: 1.10 mL/kg for men and women; Group 2: men 1.10 mL/kg, women 0.99 mL/kg) and flow rate was calculated as dose was divided by scan time plus 8 s. Mean arterial attenuations between men and women were compared with respect to attenuations of ascending aorta (AA) above coronary ostia, left main coronary artery (LM), proximal segments of right coronary artery (RCA), left anterior descending (LAD), and left circumflex artery (LCX) in two groups, respectively. Attenuations of coronary arteries were correlated with BW and BMI with simple linear regression. Results. The mean attenuations of AA, LM, RCA, LAD, and LCX were 407.8 ± 53.6 HU, 412.6 ± 55.4 HU, 411.4 ± 64.3 HU, 399.1 ± 56.7 HU, and 399.1 ± 60.2 HU, respectively, and there were no significant differences between men and women in group 1 (AA, P = 0.571; LM, P = 0.670; RCA, P = 0.737; LAD, P = 0.439, and LCX, P = 0.888). In group 2, the mean attenuations of AA, LM, RCA, LAD, and LCX in men were significantly higher than those in women (AA, P = 0.008; LM, P = 0.025; RCA, P = 0.017; LAD, P = 0.015, and LCX, P = 0.002). Positive linear regression between BW and attenuations of AA (R 2 = 0.047, P = 0.02), LM (R 2 = 0.036, P = 0.04), RCA (R 2 = 0.080, P 2 = 0.078, P 2 = 0.033, P = 0.05) was found in group 1, suggesting that attenuations of coronary

Preparation of the requirements for the safety regulation related to human and organizational factors

Energy Technology Data Exchange (ETDEWEB)

NONE

2013-08-15

The outline of the project in the current fiscal year is to investigate and analyze issues associated with Human and Organizational Factors involved in incidents of nuclear facilities, and to study and develop evaluation methods of these countermeasures. The guideline to evaluate licensee's safety culture and root cause analysis (RCA) had been developed for further improving safety on nuclear power plants at 2007. These guidelines have been used at regulatory inspection since that time. Based on experience of using these existing guidelines, some activities for improving guidelines are now under investigation; these are selecting candidate quantitative indicators for safety culture evaluation and researching good practices for RCA issues. JNES implemented human factor analysis about 18 domestic events including the Fukushima Dai-ichi nuclear power plant accident. (author)

Competitiveness and Exports Sustainability of the Indonesian Natural Rubber

Directory of Open Access Journals (Sweden)

Rumbiati Kamaludin

2018-03-01

Full Text Available This paper examines Indonesian competitiveness in export of natural rubber commodities by employing set of revealed comparative advantage (RCA and Export competitive index (ECI with respect to global trade. The market structure that is formed on natural rubber commodities is calculated using Herfindahl Index and Concentration Ratio analysis tools shows the oligopoly-shaped market structure. Calculation of comparative advantage with RCA analysis shows that the four countries exporting natural rubber, namely Thailand, Indonesia, Malaysia and Vietnam each have a comparative advantage. Where Indonesia has a better comparative advantage than Thailand in the period 2011 to 2015. This result is different from the calculations made on competitive advantage (ECI in which Indonesia's natural rubber commodities are not more competitive than Thailand

Descriptions of verbal communication errors between staff. An analysis of 84 root cause analysis-reports from Danish hospitals

DEFF Research Database (Denmark)

Rabøl, Louise Isager; Andersen, Mette Lehmann; Østergaard, Doris

2011-01-01

incidents. The objective of this study is to review RCA reports (RCAR) for characteristics of verbal communication errors between hospital staff in an organisational perspective. Method Two independent raters analysed 84 RCARs, conducted in six Danish hospitals between 2004 and 2006, for descriptions......Introduction Poor teamwork and communication between healthcare staff are correlated to patient safety incidents. However, the organisational factors responsible for these issues are unexplored. Root cause analyses (RCA) use human factors thinking to analyse the systems behind severe patient safety...... and characteristics of verbal communication errors such as handover errors and error during teamwork. Results Raters found description of verbal communication errors in 44 reports (52%). These included handover errors (35 (86%)), communication errors between different staff groups (19 (43%)), misunderstandings (13...

Anomalous Origin of the Right Coronary Artery from the Left Anterior Descending Coronary Artery in a Patient with Ascending Aortic Aneurysm

Directory of Open Access Journals (Sweden)

Ufuk Gürkan

2012-04-01

Full Text Available The incidence of coronary artery anomalies has been reported between 0.6 to 1.3% in angiographic series and 0.3% in autopsy series. An isolated single coronary artery (SCA is even a rarer congenital anomaly occurring in approximately 0.02% of the population. The ectopic origin of the right coronary artery (RCA from the left anterior descending (LAD artery is relatively rare and more benign than other types of anomalous origin of the RCAs. We report a case of an adult male patient with SCA anomaly in which the RCA takes off from the mid LAD. To the best of our knowledge, SCA anomaly coinciding with ascending aortic aneurysm which was treated with Bentall operation has never been described before.

Coronary intervention in anomalous origin of the right coronary artery (ARCA from the left sinus of valsalva (LSOV: A single center experience

Directory of Open Access Journals (Sweden)

Kalaichelvan Uthayakumaran

2014-07-01

Conclusion: PCI of anomalous RCA origin from LSOV requires appropriate guide catheter selection according to the anatomy of origin for successful cannulation and to reduce the contrast usage and radiation exposure.

Next Generation Life Support (NGLS): Rapid Cycle Amine Swing Bed

Data.gov (United States)

National Aeronautics and Space Administration — The Rapid Cycle Amine (RCA) swingbed has been identified as a technology with high potential to meet the stringent requirements for the next generation spacesuit's...

Snake population venomics and antivenomics of Bothrops atrox: Paedomorphism along its transamazonian dispersal and implications of geographic venom variability on snakebite management.

Science.gov (United States)

Calvete, Juan J; Sanz, Libia; Pérez, Alicia; Borges, Adolfo; Vargas, Alba M; Lomonte, Bruno; Angulo, Yamileth; Gutiérrez, José María; Chalkidis, Hipócrates M; Mourão, Rosa H V; Furtado, M Fatima D; Moura-Da-Silva, Ana M

2011-04-01

We describe two geographically differentiated venom phenotypes across the wide distribution range of Bothrops atrox, from the Colombian Magdalena Medio Valley through Puerto Ayacucho and El Paují, in the Venezuelan States of Amazonas and Orinoquia, respectively, and São Bento in the Brazilian State of Maranhão. Colombian and Venezuelan venoms show an ontogenetic toxin profile phenotype whereas Brazilian venoms exhibit paedomorphic phenotypes. Venoms from each of the 16 localities sampled contain both population-specific toxins and proteins shared by neighboring B. atrox populations. Mapping the molecular similarity between conspecific populations onto a physical map of B. atrox range provides clues for tracing dispersal routes that account for the current biogeographic distribution of the species. The proteomic pattern is consistent with a model of southeast and southwest dispersal and allopatric fragmentation northern of the Amazon Basin, and trans-Amazonian expansion through the Andean Corridor and across the Amazon river between Monte Alegre and Santarém. An antivenomic approach applied to assess the efficacy towards B. atrox venoms of two antivenoms raised in Costa Rica and Brazil using Bothrops venoms different than B. atrox in the immunization mixtures showed that both antivenoms immunodepleted very efficiently the major toxins (PIII-SVMPs, serine proteinases, CRISP, LAO) of paedomorphic venoms from Puerto Ayacucho (Venezuelan Amazonia) through São Bento, but had impaired reactivity towards PLA(2) and P-I SVMP molecules abundantly present in ontogenetic venoms. The degree of immunodepletion achieved suggests that each of these antivenoms may be effective against envenomations by paedomorphic, and some ontogenetic, B. atrox venoms. Copyright © 2010 Elsevier B.V. All rights reserved.

Review of "Echinococcus and Echinococcosis, Part A." edited by R. C. Andrew Thompson, Alan J. Lymbery and Peter Deplazes.

Science.gov (United States)

Ito, Akira

2017-09-04

Thompson RCA, Deplazes P, Lymbery AJ, Editors. Echinococcus and Echinococcosis, Part A. Volume 95, Advances in Parasitology 95. Academic Press; 2017. 525 pages, ISBN 978-0-12-8114711 (hardcover); 9780128114728 (eBook).

Evaluation of crushed concrete base strength.

Science.gov (United States)

2012-12-01

This research project was conducted with two primary objectives, which include: 1) determine whether current Mississippi Department of Transportation (MDOT) requirements for recycled concrete aggregates (RCA) provide adequate materials for a roadway ...

Noninvasive detection of coronary abnormalities in pediatric patients with Kawassaki disease using multi-slice spiral CT

International Nuclear Information System (INIS)

Hou Yang; Guo Wenli; Yue Yong; Chen Liying; Guo Qiyong; Yu Xianyi; Wang Hong

2006-01-01

Objective: To evaluate the feasibility and value of detecting coronary artery lesions in Kawasaki disease using multi-slice computed tomography (MSCT). Methods: Thirty-four pediatric patients underwent 16-slice or 64-slice CT coronary, angiography. 18 patients were also examined with 2 dimension echocardiography (2DE). In all cases, visibility of coronary artery segment was recorded. The diameter of the LCA, RCA were measured in MSCTA and compared with 2DE. Correlation coefficient of dimension and coincidence rate of two methods were calculated. Results: Coronary artery lesions were found in 14 patients (22 branches) of the 34 cases with KD on MSCT. Six cases were dialated, 3 cases were dialated with aneurysms, 2 cases had aneurysms without dialation. Coronary artery stenosis in 1 eases, calcification in 2 cases. Three cases had multiple aneurysms with the presence of alternate stenosis that made the artery a bead-like appearance. CC of LM and RCA were 0.85, 0.91, respectively (P>0.05). Three coronary artery aneurysm in the distal RCA was missed by 2DE. MSCT could not detect slight or moderate mitral regurgitation in 2 patients and artery wall thickening in 5 patients. Conclusion: MSCT would be an effective complementary or alternative method for CDEC to evaluate coronary artery lesions non-invasively in pediatric patients with Kawasaki disease. (authors)

Next Generation Life Support Project Status

Science.gov (United States)

Barta, Daniel J.; Chullen, Cinda; Pickering, Karen D.; Cox, Marlon; Towsend, Neil; Campbell, Colin; Flynn, Michael; Wheeler, Raymond

2012-01-01

Next Generation Life Support (NGLS) is one of several technology development projects sponsored by NASA s Game Changing Development Program. The NGLS Project is developing life support technologies (including water recovery and space suit life support technologies) needed for humans to live and work productively in space. NGLS has three project tasks: Variable Oxygen Regulator (VOR), Rapid Cycle Amine (RCA) swing bed, and Alternative Water Processor (AWP). The RCA swing bed and VOR tasks are directed at key technology needs for the Portable Life Support System (PLSS) for an Advanced Extravehicular Mobility Unit, with focus on test article development and integrated testing in an Advanced PLSS in cooperation with the Advanced Extra Vehicular Activity (EVA) Project. An RCA swing-bed provides integrated carbon dioxide removal and humidity control that can be regenerated in real time during an EVA. The VOR technology will significantly increase the number of pressure settings available to the space suit. Current space suit pressure regulators are limited to only two settings whereas the adjustability of the advanced regulator will be nearly continuous. The AWP effort, based on natural biological processes and membrane-based secondary treatment, will result in the development of a system capable of recycling wastewater from sources expected in future exploration missions, including hygiene and laundry water. This paper will provide a status of technology development activities and future plans.

A study on the performance of concrete containing recycled aggregates and ceramic as materials replacement

Science.gov (United States)

Azmi, N. B.; Khalid, F. S.; Irwan, J. M.; Anting, N.; Mazenan, P. N.

2017-11-01

Natural fine aggregate materials are commonly used in development and commercial construction in Malaysia. In fact, concrete production was increased as linear with the growing Malaysia economy. However, an issue was production of concrete was to locate adequate sources of natural fine aggregates. There lot of studies have been conducted in order to replace the fine aggregate in which natural fine aggregate replace with the waste material in concrete preparation. Therefore, this study aims to utilize the Recycled Concrete Aggregate (RCA) and ceramic waste which has great potential to replace the natural aggregate in concrete mix with different type of method, admixture, and parameters. This research were focused on compressive strength and water absorption test to determine the optimum mix ratio of concrete mix. The concrete aggregate was chosen due to improvement capillary bonding mechanisms and ceramic presented similar strength compared to the conventional concrete using natural aggregate. Percent of replacement have been used in this study was at 25%, 35% and 45% of the RCA and 5%, 10% and 15% for ceramic, respectively. Furthermore, this research was conduct to find the optimum percentage of aggregate replacement, using water-cement ratio of 0.55 with concrete grade 25/30. The best percentage of replacement was the RCA35% C15% with the compressive strength of 34.72 MPa and the water absorption was satisfied.

Single Coronary Artery Anomaly: A Case Report and Review of Literature.

Science.gov (United States)

Elbadawi, Ayman; Baig, Basarat; Elgendy, Islam Y; Alotaki, Erfan; Mohamed, Ahmed H; Barssoum, Kirolos; Fries, David; Khan, Muhammad; Khouzam, Rami N

2018-02-06

Single coronary artery is a rare anomaly, which is usually associated with other cardiac congenital abnormalities. A 56-year-old female presented with unstable angina. The patient reported complaints of typical chest pain on exertion few months prior to presentation, which progressed to become at rest. The pain was associated palpitations and dizziness. Past medical history was significant for hypertension and hyperlipidemia. Vital signs were stable. Physical examination was non-remarkable. Electrocardiogram showed normal sinus rhythm, with intermittent episodes of sinus bradycardia, and non-specific T-wave changes. Trans-thoracic echocardiogram showed normal left ventricular function and no segmental wall-motion abnormalities. Selective coronary angiography showed a normal left main coronary artery arising from left coronary cusp. The left main branched to a normal left anterior descending artery and to the left circumflex artery; a large vessel which supplied also the territory of the right coronary artery (RCA) through its terminal extension. Aortography showed absence of RCA with no other vessels arising from the right or non-coronary cusps. The patient was managed conservatively and discharged home with resolution of symptoms. We report a rare case of isolated single coronary artery with absent RCA. The patient presented with unstable angina, and was managed conservatively. Cardiologists should be aware of this rare condition, which carries a potential risk of sudden cardiac death.

Practice of adding value to materials by a neutron irradiation in research reactors

International Nuclear Information System (INIS)

Oh, Soo Youl; Jun, Byung Jin

2008-01-01

Adding more value to materials by a neutron irradiation is one of the utilization areas of research reactors. A neutron transmutation doping (NTD) of Si, a gemstone coloration, and a track etched membrane production are the three important subjects and these are being serviced on a commercial basis. Nevertheless, a further enhancement of the technologies is necessary, and the IAEA/RCA has supported the development and dissemination of the relevant technologies. This article reports on what was achieved during the IAEA/RCA Regional Training Course on the Design and Operation of Neutron Irradiation Facilities which was held in Korea in April 2008 for two weeks. The Course, which was open to the Asian RCA member states, consisted of lectures, presentations from each country, and design and experiment exercises concerning the above three subjects. The lectures covered not only the principles but also the practice in every detail. The experience of Korea on the NTD and those of Indonesia and Thailand on the gemstone coloration drew concentrated attention of the participants. Meanwhile, as one of the exercises the participants designed a device for the NTD or the gemstone irradiation and analyzed its performance from the neutronics point of view. The Course was successful in deepening the understanding on the practice of value adding technologies and also in sharing some ideas for their enhancement

Practice of adding value to materials by a neutron irradiation in research reactors

International Nuclear Information System (INIS)

Oh, Soo-Youl; Jun, Byung Jin

2008-01-01

Adding more value to materials by a neutron irradiation is one of the utilization areas of research reactors. A neutron transmutation doping (NTD) of Si, a gemstone coloration, and a track-etched membrane production are the three important subjects and these are being serviced on a commercial basis. Nevertheless, a further enhancement of the technologies is necessary, and the IAEA/RCA has supported the development and dissemination of the relevant technologies. This article reports on what was achieved during the IAEA/RCA Regional Training Course on the Design and Operation of Neutron Irradiation Facilities which was held in Korea in April 2008 for two weeks. The Course, which was open to the Asian RCA member states, consisted of lectures, presentations from each country, and design and experiment exercises concerning the above three subjects. The lectures covered not only the principles but also the practice in every detail. The experience of Korea on the NTD and those of Indonesia and Thailand on the gemstone coloration drew concentrated attention of the participants. Meanwhile, as one of the exercises the participants designed a device for the NTD or the gemstone irradiation and analyzed its performance from the neutronics point of view. The Course was successful in deepening the understanding on the practice of value-adding technologies and also in sharing some ideas for their enhancement. (author)

Practice of adding value to materials by a neutron irradiation in research reactors

International Nuclear Information System (INIS)

Oh, Soo Youl; Jun, Byung Jin

2008-01-01

Adding value to materials by a neutron irradiation is one of the utilization areas of research reactors. A neutron transmutation doping (NTD) of Si, a gemstone coloration, and a track-etched membrane production are the three important subjects and these are being serviced on a commercial basis. Nevertheless, a further enhancement of the technologies is necessary, and the IAEA/RCA has supported the development and dissemination of the relevant technologies. This article report on what was achieved during the IAEA/RCA regional Training Course on the Design and Operation of Neutron Irradiation Facilities which was held in Korea in April 2008 for two weeks. The Course, which was open to the Asian RCA member states, consisted of lectures, presentations from each country, and design and experiment exercises concerning the above three subjects. The lectures covered not only the principles but also the practice in every detail. The experience of Korea on the NTD and those of indonesia and Thailand on the gemstone coloration drew concentrated attention of the participants. Meanwhile, as one of the exercises the participants designed a device for the NTD or the gemstone irradiation and analyzed its performance from the neutronics point of view. The Course was successful in deepening the understanding on the practice of value-adding technologies and also in sharing some ideas for their enhancement

An aptasensor for staphylococcus aureus based on nicking enzyme amplification reaction and rolling circle amplification.

Science.gov (United States)

Xu, Jingguo; Guo, Jia; Maina, Sarah Wanjiku; Yang, Yumeng; Hu, Yimin; Li, Xuanxuan; Qiu, Jiarong; Xin, Zhihong

2018-05-15

An ultra-sensitive aptamer-based biosensor for the detection of staphylococcus aureus was established by adopting the nicking enzyme amplification reaction (NEAR) and the rolling circle amplification (RCA) technologies. Aptamer-probe (AP), containing an aptamer and a probe sequence, was developed to act as the recognition unit of the biosensor, which was specifically bound to S. aureus. The probe was released from AP and initiated into the subsequent DNA amplification reactions where S. aureus was present, converting the detection of S. aureus to the investigation of probe oligonucleotide. The RCA amplification products contained a G-quadruplex motif and formed a three dimensional structure in presence of hemin. The G4/hemin complex showed horseradish peroxidase (HRP)-mimic activity and catalyzed the chemiluminescence reaction of luminol mediated by H 2 O 2 . The results showed that the established biosensor could detect S. aureus specifically with a good linear correlation at 5-10 4  CFU/mL. The signal values based on NEAR-RCA two-step cycle were boosted acutely, much higher than that relied on one-cycle magnification. The limit of detection (LoD) was determined to be as low as 5 CFU/mL. The established aptasensor exhibited a good discrimination of living against dead S. aureus, and can be applied to detect S. aureus in the food industry. Copyright © 2018 Elsevier Inc. All rights reserved.

GESTÃO DE UMA VINÍCOLA DA SERRA GAÚCHA: COMPETITIVIDADE E RISCO

OpenAIRE

Sehnem, Alyne; Bertolini, Adriana Locatelli; Azevedo Roesch, Sylvia Maria; Olea, Pelayo Munhoz

2011-01-01

As famílias Amarone e Bergamaschi foram unidas por laços de sangue e também pelos negócios. Suas vidas foram marcadas por escolhas que as fizeram se encontrar no Brasil, após tantos percalços enfrentados na Europa do século XIX. No ano de 1999, com uma safra excelente e a conjuntura econômica nacional favorecida, surgiu a Amarone Adega de Vinhos Finos: vinícola localizada na cidade gaúcha de Bento Gonçalves, fruto do encontro e da união das forças de duas famílias Amarone e Bergamaschi. O obj...

Usefulness of 64-slice MDCT for follow-up of young children with coronary artery aneurysm due to Kawasaki disease: initial experience.

Science.gov (United States)

Peng, Yun; Zeng, Jinjin; Du, Zhongdong; Sun, Guoqiang; Guo, Huling

2009-03-01

To evaluate the initial application and value of 64-slice multidetector computed tomography as an alternative diagnostic modality in the follow-up of young children with coronary artery aneurysm due to Kawasaki disease. Twelve boys (mean age 5.1 years, range 1.8-7.8 years) for follow-up (time range from 1.1 to 5.1 years) of known Kawasaki disease and coronary artery aneurysm underwent 64-slice MDCT ECG-gated coronary angiography. All data were acquired without breath holding. Two pediatric radiologists independently assessed image quality and the diameter of all coronary segments were measured for each patient. The number, position, shape and size of each coronary artery aneurysm were observed and compared with those of ECHO performed previously. A total of 118/156 segments permitted visualization with diagnostic image quality, the CT measurements showed good inter-observer and intra-observer reliability, coefficients were 0.93 and 0.88, respectively. A total of 30 coronary artery aneurysms were identified with measured mean of 7.5+/-3.8 mm in diameter, and of 12.4+/-9.1 mm in longitudinal lengths.10 tumors were small, 8 tumors were medium and 12 tumors were giant aneurysm. The affected segments included LM7/12(58.3%), 9/12(75%) of LAD1, 4/12(33.3%) of LAD2, 2/12(16.7%) of LCX1; 6/12(50%) of RCA1, 9/12(75%) of RCA2 and 4/12(33.3%) of RCA3, including affected two segments in 9 tumors and three segments in 1 tumor. Calcifications were found in 5 aneurysms and 3/5 with thrombosis; six stenotic segments were found. ECHO failed to detect 8 tumors with 2/8 in LAD, 1/8 in LCX and 5/8 in RCA, and those included 4 small aneurysms. The use of 64-slice MDCT angiography proved valuable for monitoring young children with Kawasaki disease. However, further study is necessary to specify the sensitivity and specificity of MDCT in the follow-up.

Usefulness of 64-slice MDCT for follow-up of young children with coronary artery aneurysm due to Kawasaki disease: Initial experience

International Nuclear Information System (INIS)

Peng Yun; Zeng Jinjin; Du Zhongdong; Sun Guoqiang; Guo Huling

2009-01-01

To evaluate the initial application and value of 64-slice multidetector computed tomography as an alternative diagnostic modality in the follow-up of young children with coronary artery aneurysm due to Kawasaki disease. Twelve boys (mean age 5.1 years, range 1.8-7.8 years) for follow-up (time range from 1.1 to 5.1 years) of known Kawasaki disease and coronary artery aneurysm underwent 64-slice MDCT ECG-gated coronary angiography. All data were acquired without breath holding. Two pediatric radiologists independently assessed image quality and the diameter of all coronary segments were measured for each patient. The number, position, shape and size of each coronary artery aneurysm were observed and compared with those of ECHO performed previously. A total of 118/156 segments permitted visualization with diagnostic image quality, the CT measurements showed good inter-observer and intra-observer reliability, coefficients were 0.93 and 0.88, respectively. A total of 30 coronary artery aneurysms were identified with measured mean of 7.5 ± 3.8 mm in diameter, and of 12.4 ± 9.1 mm in longitudinal lengths.10 tumors were small, 8 tumors were medium and 12 tumors were giant aneurysm. The affected segments included LM7/12(58.3%), 9/12(75%) of LAD1, 4/12(33.3%) of LAD2, 2/12(16.7%) of LCX1; 6/12(50%) of RCA1, 9/12(75%) of RCA2 and 4/12(33.3%) of RCA3, including affected two segments in 9 tumors and three segments in 1 tumor. Calcifications were found in 5 aneurysms and 3/5 with thrombosis; six stenotic segments were found. ECHO failed to detect 8 tumors with 2/8 in LAD, 1/8 in LCX and 5/8 in RCA, and those included 4 small aneurysms. The use of 64-slice MDCT angiography proved valuable for monitoring young children with Kawasaki disease. However, further study is necessary to specify the sensitivity and specificity of MDCT in the follow-up.

Usefulness of 64-slice MDCT for follow-up of young children with coronary artery aneurysm due to Kawasaki disease: Initial experience

Energy Technology Data Exchange (ETDEWEB)

Peng Yun [Imaging Center, Beijing Children' s Hospital Affiliated to Capital Medical University, 56, Nanlishi Road, Xicheng District, Beijing 100045 (China)], E-mail: ppengyun@yahoo.com; Zeng Jinjin [Imaging Center, Beijing Children' s Hospital Affiliated to Capital Medical University, 56, Nanlishi Road, Xicheng District, Beijing 100045 (China); Du Zhongdong [Pediatric Cardiovascular Department, Beijing Children' s Hospital Affiliated to Capital Medical University, 56, Nanlishi Road, Xicheng District, Beijing 100045 (China); Sun Guoqiang [Imaging Center, Beijing Children' s Hospital Affiliated to Capital Medical University, 56, Nanlishi Road, Xicheng District, Beijing 100045 (China); Guo Huling [Pediatric Cardiovascular Department, Beijing Children' s Hospital Affiliated to Capital Medical University, 56, Nanlishi Road, Xicheng District, Beijing 100045 (China)

2009-03-15

To evaluate the initial application and value of 64-slice multidetector computed tomography as an alternative diagnostic modality in the follow-up of young children with coronary artery aneurysm due to Kawasaki disease. Twelve boys (mean age 5.1 years, range 1.8-7.8 years) for follow-up (time range from 1.1 to 5.1 years) of known Kawasaki disease and coronary artery aneurysm underwent 64-slice MDCT ECG-gated coronary angiography. All data were acquired without breath holding. Two pediatric radiologists independently assessed image quality and the diameter of all coronary segments were measured for each patient. The number, position, shape and size of each coronary artery aneurysm were observed and compared with those of ECHO performed previously. A total of 118/156 segments permitted visualization with diagnostic image quality, the CT measurements showed good inter-observer and intra-observer reliability, coefficients were 0.93 and 0.88, respectively. A total of 30 coronary artery aneurysms were identified with measured mean of 7.5 {+-} 3.8 mm in diameter, and of 12.4 {+-} 9.1 mm in longitudinal lengths.10 tumors were small, 8 tumors were medium and 12 tumors were giant aneurysm. The affected segments included LM7/12(58.3%), 9/12(75%) of LAD1, 4/12(33.3%) of LAD2, 2/12(16.7%) of LCX1; 6/12(50%) of RCA1, 9/12(75%) of RCA2 and 4/12(33.3%) of RCA3, including affected two segments in 9 tumors and three segments in 1 tumor. Calcifications were found in 5 aneurysms and 3/5 with thrombosis; six stenotic segments were found. ECHO failed to detect 8 tumors with 2/8 in LAD, 1/8 in LCX and 5/8 in RCA, and those included 4 small aneurysms. The use of 64-slice MDCT angiography proved valuable for monitoring young children with Kawasaki disease. However, further study is necessary to specify the sensitivity and specificity of MDCT in the follow-up.

Durability assessment of recycled concrete aggregates for use in new concrete.

Science.gov (United States)

2012-06-01

The primary goal of this research project was to investigate the long-term durability of concrete incorporating : recycled concrete aggregate (RCA) through accelerated laboratory testing. Overall it was found that modifications to : standard aggregat...

50 CFR 660.330 - Open access fishery-management measures.

Science.gov (United States)

2010-10-01

....S./Mexico border) is permitted within the nontrawl RCA with fixed gear only under the following... coordinates at §§ 660.398-.399: Thompson Seamount, President Jackson Seamount, Cordell Bank (50-fm (91-m...

KERAGAAN REMATURASI GONAD INDUK TERIPANG PASIR, Holothuria scabra DENGAN PEMBERIAN JENIS PAKAN BERBEDA

Directory of Open Access Journals (Sweden)

Sari Budi Moria Sembiring

2017-10-01

Full Text Available Rematurasi gonad induk teripang pasir Holothuria scabra yang sudah memijah masih banyak masalah, padahal rematurasi diperlukan untuk keberlanjutan pemijahan dan penyediaan benih. Tujuan penelitian adalah memperoleh jenis pakan yang dapat mempercepat proses rematurasi gonad terhadap induk alam yang sudah dipijahkan sehingga dapat memenuhi kebutuhan untuk pembenihan teripang di hatcheri, serta mengetahui performa benih yang dihasilkan secara fenotipe dan genotipe. Penelitian rematurasi gonad dengan pemberian pakan berbeda telah dilakukan di Balai Besar Penelitian dan Pengembangan Budidaya Laut, Gondol. Penelitian dilakukan dengan metode eksperimental secara rancangan acak lengkap dengan perlakuan perbedaan jenis pakan, yaitu: A Ulva sp. dan bentos; B Gracilaria sp. dan bentos, dan C bentos saja. Dosis pemberian pakan sebanyak 4% dari bobot badan dengan frekuensi pemberian 1 kali/hari. Setiap perlakuan terdiri atas tiga ulangan. Jumlah induk setiap ulangan sebanyak tiga ekor dengan ukuran panjang dan bobot 13,08 ± 2,04 cm dan 182,75 ± 47,74 g. Benih yang dihasilkan sebelum induk dirematurasi dan setelah rematurasi diamati performa fenotipe dan genotipenya. Analisis genotipe menggunakan metode mikrosatellit dengan empat lokus (Hsc-11; Hsc-28; Hsc-49; dan Hsc-59. Parameter yang diamati meliputi frekuensi pemijahan induk teripang, tingkat kematangan gonad, indeks gonadosomatik, fekunditas, diameter telur, pertumbuhan benih F-1 sebelum dan sesudah rematurasi, serta performa genotipe benih tersebut. Data indeks gonad somatik dan diameter telur dianalisis dengan ANOVA, sedangkan data pertumbuhan, pemijahan, dan fekunditas disajikan dalam bentuk tabel dan grafik. Hasil penelitian menunjukkan bahwa semua perlakuan dapat mempercepat rematurasi gonad dan induk teripang memijah setelah dua bulan pemeliharaan. Jenis pakan bentos menghasilkan indeks gonadosomatik dan diameter telur lebih baik dibandingkan dengan perlakuan pakan lainnya (P0,05. Successful rate

The Study of Oils Consumption Pattern and Its Related Factors in east Tehran

Directory of Open Access Journals (Sweden)

Farhad Jafari

2013-09-01

Full Text Available Background & Objective: Inappropriate use of fat in diets is a significant risk factor that can cause cardiovascular diseases, morbidity, and mortality in the world. This study was designed to determine the fat consumption pattern in east Tehran habitants. Materials & Methods: In this cross sectional study 500 east Tehran habitants were evaluated. Data was collected by a questionnaire designed by the authors of the present study. The validity and reliability of the questionnaire was confirmed in a pilot study. The Data was analyzed with SPSS software. Results: The average of family members was 3.9±1.4. The highest amount ofoil consumed was that of solid candy oil, while The lowest was animal oil. For cooking, 36.8% and 31% of samples were using liquid oil and solid candy oil, respectively. For fraying 33.8%, 20%, 32.4% of samples were using liquid oil, solid candy oil and frying oil, respectively. a relationship was found between higher educational level and mothers working out of the house and higher consumption of liquid oil, fraying oil and olive oil (p<0.001. High age, housekeeper mothers and higher family span were associated with the higher consumption of solid oils, butter and ghee (p<0.02. Conclusion: This study revealed that the significant portion of daily oil consumption of Tehran habitants consist of solid oils. It seems to be necessary to organize proper training programs to increase social awareness about the hazards of solid saturated fats.

Microstructure and mechanical properties of recycled aggregate concrete in seawater environment.

Science.gov (United States)

Yue, Pengjun; Tan, Zhuoying; Guo, Zhiying

2013-01-01

This study aims to conduct research about the microstructure and basic properties of recycled aggregate concrete under seawater corrosion. Concrete specimens were fabricated and tested with different replacement percentages of 0%, 30%, and 60% after immersing in seawater for 4, 8, 12, and 16 months, respectively. The basic properties of recycled aggregate concrete (RAC) including the compressive strength, the elastic modulus, and chloride penetration depth were explicitly investigated. And the microstructure of recycled concrete aggregate (RCA) was revealed to find the seawater corrosion by using scanning electron microscope (SEM). The results showed that higher amount of the RCA means more porosity and less strength, which could lower both the compressive strength and resistance to chloride penetration. This research could be a guide in theoretical and numerical analysis for the design of RAC structures.

Glycoproteins of bovine epididymal spermatozoa--a cytochemical study.

Science.gov (United States)

Sinowatz, F; Friess, A E; Wrobel, K H

1984-01-01

Modifications in bull sperm plasmamembrane during epididymal passage were investigated by the use of four different lectins: Concanavalin A (Con A); Ricinus communis I (RCA1); Wheat germ agglutinin (WGA); Ulex europaeus agglutinin I (UEA1). During sperm passage from caput to cauda epididymidis agglutination by RCA1 and WGA distinctly increased. Similar but somewhat less pronounced difference in the agglutinability was found for Con A. No agglutination was observed with UEA1. Ultrastructural examination of Con A binding sites on sperm plasma membrane with a Con A-horseradish peroxidase-gold technique (Con A-HRP-G) revealed a significant increase in the number of gold granules on the sperm tails during the epididymal passage of spermatozoa. No change in WGA-binding sites was observed between caput and cauda spermatozoa using a WGA-peroxidase method.

Noncontact COS charge analysis for in-line monitoring of wet cleaning processes

Science.gov (United States)

Zhang, Xiafang; Juang, Min; Tai, Sung-Shan; Chen, Kuo-in; Wossen, Ejigu; Horner, Gregory

1998-08-01

Contamination levels in chemical cleaning equipment and wafer cleanliness in general are very critical to semiconductor manufacturers. In this work, a Keithley Instruments non contact electrical tester (Quantox) is used to measure the mobile ion (Qm) contamination in a variety of cleaning processes. Results show that photoresist strip cleaning process has a higher mobile ion concentration than standard pre-diffusion cleaning process. RCA1, RCA2 and HF solutions mapping measured by the Quantox indicates some negative static charges on the surface after cleaning. This negative field appears to assist Qm removal during wet chemical cleaning. The dependence of flatband voltage and other oxide charges on various cleaning processes has also been investigated using the Quantox. The data suggests that a dipole layer has been formed by a surface reaction during chemical cleaning.

Rapid screening for human-pathogenic Mucorales using rolling circle amplification.

Science.gov (United States)

Dolatabadi, S; Najafzadeh, M J; de Hoog, G S

2014-12-01

Mucormycosis has emerged as a relatively common severe mycosis in patients with haematological and allogeneic stem cell transplantation. Source of transmission is from unidentified sources in the environment. Early diagnosis of infection and its source of contamination are paramount for rapid and appropriate therapy. In this study, rolling circle amplification (RCA) is introduced as a sensitive, specific and reproducible isothermal DNA amplification technique for rapid molecular identification of six of the most virulent species (Rhizopus microsporus, R. arrhizus var. arrhizus, R. arrhizus var. delemar, Mucor irregularis, Mucor circinelloides, Lichtheimia ramosa, Lichtheimia corymbifera). DNAs of target species were successfully amplified, with no cross reactivity between species. RCA can be considered as a rapid detection method with high specificity and sensitivity, suitable for large screening. © 2014 Blackwell Verlag GmbH.

The analysis of export commodity competitiveness in Central Java Province at period 2011-2015

Science.gov (United States)

Elysi, M. G.; Darsono; Riptanti, E. W.

2018-03-01

This study aims to determine the competitiveness of furniture export in Central Java Province Indonesia in terms of comparative and competitive advantages and to formulate the strategies to enhance the competitiveness of furniture export in Central Java Province. Descriptive analytic method was used for this research. Data used in this research are primary and secondary data. Data were analyzed using RCA (Revealed Comparative Advantage), TSI (Trade Specialization Index) and SOAR (Strength, Opportunity, Aspiration, Result). The results showed that furniture commodity in Central Java Province had strong comparative competitiveness with the value of RCA>1 and had strong competitiveness with positive index values in the range of 0 to 1. Based on SOAR analysis, strategy measures can be formulated, namely maintaining the existing and expanding targeted markets, improving product designs (innovations) and improving raw materials efficiency.

Right coronary artery anatomy: anatomical and morphometric analysis Anatomia da artéria coronária direita: análises anatômicas e morfométricas

Directory of Open Access Journals (Sweden)

Luis Ernesto Ballesteros

2011-06-01

Full Text Available BACKGROUND: It is necessary knowing the large variability of right coronary (RCA artery specialty for its implications in surgical procedures and clinic events. This variability is usually related to the length, branches quantity, origin and irrigated territories. OBJECTIVE: To evaluate by direct examination the morphologic expression of RCA in Colombian people. METHODS: RCA were measured in 221 fresh hearts by RCA ostium canalization with polyester synthetic resin that was injected in their branches. RESULTS: The caliber of the RCA proximal segment and at the level of the acute angle of the heart was 3.42 ± 0.66 mm and 2.9 ± 0.50 mm, respectively. It ended between crux cordis and the left margin in 75.6% of specimens. Posterior interventricular artery (PIA reached the inferior third, or the apex, or the anterior interventricular sulcus in 149 (67.4% cases. Sinoatrial node artery (SNA originated in the right coronary in 134 (60.6% cases, 77 (34.9% from circumflex artery (CxA and from both in 10 (4.5%. Posterior right diagonal artery (PRDA was noted in 38 (17.2% hearts, but only 6% of the sample with long PIA, concomitantly presented the PRDA (P = 0.001. In right dominance SNA were originated from RCA in 54.7% and form CxA in 46.3% (P = 0.06. CONCLUSIONS: Caliber of the RCA and its branches is lesser than the majority of previous studies, while the PRDA frequency is slightly higher than the reported in literature. Clinical and pathological scenarios by these variations should be taken into account: hemodynamic procedures, cardiac surgery and arrhythmias from coronary occlusive disease.INTRODUÇÃO: É necessário conhecer a grande variabilidade da artéria coronária direita (ACD, especialmente por suas implicações nos procedimentos cirúrgicos e eventos clínicos. Esta variabilidade está geralmente relacionada à extensão, à quantidade de ramos, à origem e aos territórios irrigados. OBJETIVO: Avaliar por exame direto a expressão morfol