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Sample records for fray bentos rca

  1. Paleosoils and pedogenic calcretes formations in Fray Bentos (Oligocene - early miocene) Raigon (late pliocene and middle pleistocene) and Libertad (early - middle pleistocene)

    International Nuclear Information System (INIS)

    Tofalo, O.; Morras, H.; Sanchez-Bettucci, L.

    2012-01-01

    The Fray Bentos formation is composed by loessic deposits based on paleosoils and pedogenic calcretes (Oligocene - early miocene). In this deposits are tubular and lamellar formations which would have been formed in arid climates.The fluvial origen of Raigon Formation, (late pliocene and middle pleistocene) presents a paleosoil roof which is generated under a subhumid climate.The Libertad Formation during the glacial intervals consisted of loess deposits

  2. Sedimentary features of the Mercedes formation (upper Cretaceous ) between Mercedes and Fray Bentos cities, Rca. O del Uruguay

    International Nuclear Information System (INIS)

    Tofalo, O.; Pazos, P.

    1998-01-01

    A new locality by the Mercedes formation is analyzed close to route 2, near at the Mercedes City. The stratigraphic assignment is proposed after the examination of the sedimentary features that include geometry, composition and sedimentary structures. The section that reach 10 meters in thickness contains conglomerates, pebbly sandstones, sandstones and scare mudstones with a finning upward arrangement. All of features are indicative of a alluvial origin. This locality is the first mention of the Mercedes formation in the south section of the Department Rio Negro. (author)

  3. Bento Boxes

    Science.gov (United States)

    Hasio, Cindy

    2010-01-01

    Bento boxes are common objects in Japanese culture, designed to hold enough lunch for one person. They have individual compartments and sometimes multiple tiers for rice, vegetables, and other side dishes. They are made of materials ranging from wood, cloth, aluminum, or plastic. In general, the greater the number of foods, the better the box is…

  4. RCA annual report 1988

    International Nuclear Information System (INIS)

    1989-09-01

    The report covers the calendar year 1988. It contains an extended preface on Asian regional co-operation in the application of nuclear techniques, a summary of major RCA meetings, administrative questions, a summary of technical aspects of the programme and an analysis of the resources including a prediction of project activities for 1989-1991. 4 figs, 3 tabs

  5. Fray Juan Rizi en Italia

    Directory of Open Access Journals (Sweden)

    Salort Pons, Salvador

    1999-03-01

    Full Text Available Since Tormo, Gusi and Lafuente wrote fray Juan Rizi's monograph in 1930, and Ángulo & Pérez Sánchez revised years later this study in their book Pintura madrileña del segundo tercio del siglo XVII, very little has been published about the life and work of the Benedictine painter. Furthermore, the Italian journey of Rizi, that involved the last 20 years of his life, has always been an enigma, resolved only in certain aspects, thanks to few news supplied by his biographers and the manuscripts the monk wrote during his staying in the Montecassino abbey. Our recent discovery of 8 new canvases painted by Rizi to decorate the Saints Cosme and Damian's chapel in the main church of Trevi nel Lazio (Frosinone, Italy, as well as the location of several new drawings in the Montecassino and Vatican libraries, will allow us to study his activity as painter in Italy and also to profile, with more accuracy, the history of the last years of his life.No disponible

  6. RCA's regional industrial project

    International Nuclear Information System (INIS)

    Ali, A.T.

    1988-01-01

    The Regional Cooperation Agreement (RCA) for Research Development and Training Related to Nuclear Science and Technology, formulated under the auspices of the International Atomic Energy Agency (IAEA), came into force in June 1972. The overall objective of RCA is to promote technical cooperation among the developing and developed countries in the Asia Pacific region in the peaceful uses of nuclear energy and related technology. Currently, the biggest project under RCA is the Regional Project on the Industrial Applications of Isotopes and Radiation Technology for Asia and the Pacific. The project was established in 1982 for a period of five years and was completed in December 1986. The first phase of the project has generated a high degree of awareness on the industrial potential of isotopes and radiation technology throughout the region; produced a cadre of trained manpower in all areas covered by the project; identified the expertise available in the region; and developed in the region, a unique network of people and institutions involved with the utilization of isotope and radiation technology. A Phase II of the project, which cover all but one of the sub-projects under Phase I, was approved in early 1987 for another five years until 1991. (Nogami, K.)

  7. RCA : resource consumptions accounting

    OpenAIRE

    Valeska Rodriguez Lucas de Freitas

    2013-01-01

    Devido à grande concorrência do mercado o controle de custos passa a ser peça fundamental no auxílio à tomada de decisão quanto à redução dos custos, visando uma lucratividade maior por parte das empresas. Essa dissertação trata sobre um novo modelo de custos, o RCA – Resource Consumption Accounting, que ainda não foi adotado por nenhuma empresa. Esse novo método de custeio foi aplicado como modelo piloto em uma empresa Americana onde os resultados foram favoráveis a ele em relação aos modelo...

  8. RCA - a regional approach to radiation protection

    International Nuclear Information System (INIS)

    Griffith, R.; Easey, J.

    1996-01-01

    The Regional Cooperative Agreement (RCA) for Asia and Oceania is the oldest of four International Atomic Energy Agency Member State regional programs. Organized in 1972, 17 countries are now members of RCA - Australia, Bangladesh, Peoples Republic of China, India, Indonesia, Japan, Republic of Korea, Malaysia, Mongolia, Myanmar, New Zealand, Pakistan, Philippines, Singapore, Sri Lanka, Thailand, and Viet Nam. A number of projects related to the application of a wide range of nuclear technologies are conducted through RCA. The program is established by national coordinators for each project area, in consultation with IAEA technical officers. Most of the funding comes directly from RCA regional donor countries, with about one third supplied through the IAEA Technical Cooperation program. In 1986, following the Chernobyl accident, national coordinators and the IAEA staff recognized the value of establishing an RCA project aimed at strengthening regional radiation protection programs. The potential importance of RCA involvement in radiation protection is underscored by the fact that its member states comprise more than half of the world's population. The regional approach to addressing radiation protection issues allows member states to take advantage of regional resources to solve common regional problems. RCA provides the opportunity for specialists who may have few professional colleagues in their country to develop valuable contacts with regional radiation protection experts. In a very real way, specialists can network with their neighbours, often establishing bilateral programs outside of the RCA auspices. The current five year RCA Project to strengthen radiation protection infrastructure, with the IAEA designation - RAS/9/006, will be completed at the end of 1997. The project was developed to address five mayor areas of activity: Off-site emergency response; individual monitoring, internal and external; characterization of the physical, anatomical, physiological

  9. BENTO buffer development program in Finland - Key issues

    International Nuclear Information System (INIS)

    Autio, J.; Korkiala-Tanttu, L.; Vaehaenen, M.; Koskinen, K.; Korkeakoski, P.; Haapala, K.

    2010-01-01

    Document available in extended abstract form only. Posiva launched a programme, BENTO, to develop technology of using bentonite in spent nuclear fuel repositories. The main purpose of the BENTO programme is to produce buffer designs and verify that they fulfil the requirements, especially safety requirements. To achieve this objective, resources and the level of expertise and know-how has to be increased. There are several uncertainties related to the functioning of the buffer components at present. An issue is defined as being significant if there is sufficient uncertainty that the buffer system might not fulfil the requirements because of the issue. These significant issues need to be resolved in order to develop a proper design and to verify the fulfilment of the requirements. The list of significant issues may change with time. Therefore it is crucial to develop adequate expertise, know-how and laboratory facilities to manage the changes. Moreover, there is confidence that by solving the open issues a defendable construction license application can be submitted in 2012. The basic nature of the programme is a combination of material and process research with the design and manufacturing of buffer components to produce feasible buffer design with proven long-term functional properties. The development work carried out under BENTO-programme has been initially divided into four different projects. During the course of work the number of projects and their content can be adjusted. The four BENTO projects are: 1. Manufacturing (MANU); 2. Design (DESI); 3. Modelling (MODE); 4. Material and Process Research (MARE). BENTO programme aims at producing feasible buffer designs which fulfil the requirements specified in Posiva's requirement management system. The designs are produced in DESI-project by following the design development scheme which starts from specification of design basis and ends in documented detailed designs and therefore DESIgn is specified as one

  10. Fray Bartolomé de Las Casas in the Work and Thought of Fray Servando Teresa de Mier

    Directory of Open Access Journals (Sweden)

    Begoña Pulido Herráez

    2011-10-01

    Full Text Available This paper studies the presence and influence of fray Bartolomé de Las Casas’s thought on the work of fray Servando Teresa de Mier, particularly the way in which it influenced the shaping of his original idea of the existence of a pact, a set of fundamental laws, a constitution established in the years after the conquest and where America would be included in the Crown of Castile as an independent realm, and not a colony. We examine the different texts where Mier starts to appropriate Las Casas’s thought, especially two poorly known texts: the Speech of Doctor Don Servando de Mier, born in Mexico, confirming the apology of Bishop Casas, written by the Reverend Bishop of Blois, Monsignor Henrique Gregoire, in a letter written in the year 1806, and the prologue to the edition of A Short Account of the Destruction of the Indies by Bartolomé de las Casas.

  11. Fray Benito de Oya: un historiador del Monasterio de Celanova en el siglo XVII

    OpenAIRE

    González Balasch, María Teresa

    2002-01-01

    575 p. El artículo estudia un códice del Archivo Histórico Nacional firmado por fray Alonso de Arce titulado "Epítome de la fundación y aumentos de Celanova, escrito el año de 1624 por fray Benito de Oya

  12. El confesor regio Fray Luis Aliaga y la controversia Inmaculista

    Directory of Open Access Journals (Sweden)

    Callado Estela, Emilio

    2016-06-01

    Full Text Available The present article analyses the participation of the aragonese dominican monk Luis Aliaga (Zaragoza, 1565-† Zaragoza, 1626, last confessor of Philip III and Inquiring general of the Hispanic Monarchy from 1619, in one of the most white hot theological controversies along the 17th century: the Immaculate Conception of the Virgin MaryEl presente artículo analiza la participación del dominico aragonés fray Luis Aliaga (Zaragoza, 1565-† Zaragoza, 1626 , último confesor de Felipe III e Inquisidor general de la Monarquía Hispánica desde 1619, en una de las controversias teológicas más candentes a lo largo del siglo XVII: la Inmaculada Concepción de la Virgen María.

  13. La prisión de Fray Luis

    Directory of Open Access Journals (Sweden)

    Victor Sánchez Montenegro

    1960-11-01

    Full Text Available Es una creencia general difundida por muchas historias de la literatura española y universal de que la principal causa de la prisión de Fray Luis de León en Valladolid por la Inquisición de esa ciudad, fue el haber traducido el Cantar de los Cantares, atribuidoa Salomón , es decir el Sir hassirim que los LXX tradujeron al griego Aisma Aismaton, y el Cantica Canticorum de la Vulgata. Sin embargo, como  pasaré a demostrar, no fue esa precisamente la causa de la tremenda injusticia sino otras presentarlas por sus enemigos , quienes en sus ataques hasta llegaron a probar que no descendía de Cristianos viejos sino que tenía sangre de judíos.

  14. The Educational Process in Chico Bento's Stories: Representations About Education in the Brazilian Rural Universe

    Directory of Open Access Journals (Sweden)

    Cintia Weber Biazi

    2010-03-01

    Full Text Available In this work we use Cultural Studies to identify and understand the representations that are transmitted about the educational process in Chico Bento's stories - a character of a comic strip in Brazil. He is a personage who lives in the Brazilian rural zone and was created by Maurício de Sousa. The trajectory of this work included an ethnography of the magazines about Chico Bento, characterizing the rural universe where he lives, focusing on the educational practices and especially his school experiences. Since the delimitation of that universe, it was possible to analyze in which ways Chico Bento's creators articulate the relationship between scientific knowledge x popular knowledge, emphasizing the pedagogic practices of the teacher, Miss Marocas.

  15. Current status of RCA projects and strategies for future implementation

    International Nuclear Information System (INIS)

    Kim, Kyoung Pyo; Lee, Jeong Kong

    1998-12-01

    This report is intended to provide basic overall information about ways to promote technical cooperation within the framework of RCA to accelerate and coordinate cooperative activities in nuclear science and technology in Asia and the Pacific region through a thorough review on the current status and through suggesting future implementation strategies. The contents of this report include an overall introduction of RCA, guidelines and operating rules for RCA programmes, current status and future plans for RCA projects as well as the RCA vision for the next 25 years. By reviewing the current status and future implementation strategies for RCA projects, it will help to set up a national nuclear policy aimed at seeking maximum benefits from participation in RCA projects and to implement programmes for nuclear cooperation with Asian-Pacific countries. It is expected that as a lead country for the energy sector, which is one of five thematic areas for the year 1999 - 2000 cycle programmes, Korea will continue to make significant contributions towards the implementation of RCA programmes in the future. With this report, we plan to keep up with future developments as well as implement an effective cooperation with the countries in the region so that the opinion of Korea, one of the nuclear advanced countries in the region, can be fully reflected in the establishment of future plans for RCA programmes. (author). 3 refs., 5 tabs., 1 fig

  16. Twenty-sixth general conference meeting of representatives of RCA member states. Report

    International Nuclear Information System (INIS)

    1997-10-01

    The meeting discussed the following issues: RCA Annual Report 1996; Report of the 19th RCA Working Group Meeting, Yangon Myanmar, 10-14 March 1997; RCA in the next 25 years; Development finance and the RCA; locating a senior RCA representative in the region; RCA guidelines and operating rules; TCDC activities; terminal tripartite review meeting on UNDP/RCA/IAEA project; status of new joint UNDP/RCA/IAEA project; options for the new joint project; RCA activities and budget in 1997 and 1998; reformulation and health care project; RCA proposed programme for 1999-2000; country statements; extension of RCA agreement; RCA 25th anniversary; venue and date of the 20th regular meeting of national RCA representatives

  17. Twenty-sixth general conference meeting of representatives of RCA member states. Report

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-10-01

    The meeting discussed the following issues: RCA Annual Report 1996; Report of the 19th RCA Working Group Meeting, Yangon Myanmar, 10-14 March 1997; RCA in the next 25 years; Development finance and the RCA; locating a senior RCA representative in the region; RCA guidelines and operating rules; TCDC activities; terminal tripartite review meeting on UNDP/RCA/IAEA project; status of new joint UNDP/RCA/IAEA project; options for the new joint project; RCA activities and budget in 1997 and 1998; reformulation and health care project; RCA proposed programme for 1999-2000; country statements; extension of RCA agreement; RCA 25th anniversary; venue and date of the 20th regular meeting of national RCA representatives.

  18. Rapid Cycle Amine (RCA) 3.0 System Development

    Science.gov (United States)

    Chullen, Cinda; Campbell, Colin; Papale, William; Hawes, Kevin; Wichowski, Robert

    2015-01-01

    The Rapid Cycle Amine (RCA) 3.0 system is currently under development by NASA, the Lyndon B. Johnson Space Center (JSC) in conjunction with United Technologies Corporation Aerospace Systems (UTAS). The RCA technology is a new carbon dioxide (CO2) and humidity removal system that has been baselined for the Advanced Extravehicular Mobility Unit (AEMU) Portable Life Support System. The evolution of the RCA development has progressed through several iterations of technology readiness levels including RCA 1.0, RCA 2.0, and RCA 3.0 test articles. The RCA is an advancement over currently technologies due to its unique regeneration capability. The RCA is capable of simultaneously removing CO2 and humidity from an influent air steam and subsequent regeneration when exposed to a vacuum source. The RCA technology uses two solid amine sorbent beds in an alternating fashion to adsorb CO2 and water (uptake mode) and desorb CO2 and water (regeneration mode) at the same time. The two beds operate in an efficient manner so that while one bed is in the uptake mode, the other is in the regeneration mode, thus continuously providing an on-service sorbent bed by which CO2 and humidity may be removed. The RCA 2.0 and 3.0 test articles were designed with a novel valve assembly which allows for switching between uptake and regeneration modes with only one moving part while minimizing gas volume losses to the vacuum source by means of an internal pressure equalization step during actuation. The RCA technology also is low power, small, and has performed extremely well in all development testing thus far. A final design was selected for the RCA 3.0, fabricated, assembled, and performance tested in 2014 with delivery to NASAJSC in January 2015. This paper will provide an overview on the RCA 3.0 system design and results of pre-delivery testing with references to the development of RCA 1.0 and RCA 2.0.

  19. The fraying web of life and our future engineers

    Science.gov (United States)

    Splitt, Frank G.

    2004-07-01

    Evidence abounds that we are reaching the carrying capacity of the earth -- engaging in deficit spending. The amount of crops, animals, and other biomatter we extract from the earth each year exceeds wth the earth can replace by an estimated 20%. Additionally, signs of climate change are precursors of things to come. Global industrialization and the new technologies of the 20th century have helped to stretch the capacities of our finite natural system to precarious levels. Taken together, this evidence reflects a fraying web of life. Sustainable development and natural capitalism work to reverse these trends, however, we are often still wedded to the notion that environmental conservation and economic development are the 'players' in a zero-sum game. Engineering and its technological derivatives can also help remedy the problem. The well being of future generations will depend to a large extent on how we educate our future engineers. These engineers will be a new breed -- developing and using sustainable technology, benign manufacturing processes and an expanded array of environmental assessment tools that will simultaneously support and maintain healthy economies and a healthy environment. The importance of environment and sustainable development cosiderations, the need for their widespread inclusion in engineering education, the impediments to change, and the important role played by ABET will be presented.

  20. A study on strategies for effective participation in the IAEA/RCA projects

    International Nuclear Information System (INIS)

    Chung, Joon Keuk; Jun, Byung Jin; Lee, Man Ki; Jin, Joon Ha; Choi, Pyung Hoon; Kim, Myung Ro; Min, Do Young

    2002-07-01

    In an effort to achieve the objectives, the following provisions were made. First of all, how this project supported RCA events that were held in Korea during the project period was described. Also, participation in RCA major policy level meetings, RCA-30 Scientific Forum, RCA Regional Office Opening were briefly reviewed. Secondly, RCA's general features including history and objective of its establishment, basic policy, administrative structure, major meetings was also reviewed. Thirdly, Overview of RCA projects, project implementation mechanism, on-going and planned project, review of technology utilization so fat and success stories were described. Fourthly, the issues related to the effective RCA management such as lead countries, Regional Resources Units (RRUs), RCA future vision and outsourcing of technical cooperation projects were reviewed. Finally, proper strategies and recommendations for active implementation of RCA projects were presented. This study can be utilized as basic reference material in the efficient implementation of RCA programmes in the future and for the personnel involved in the RCA projects as the fundamental elements for implementing the RCA cooperation are presented. The effective implementation direction for RCA programmes and strategies for strengthening Korea's participation in RCA projects can be utilized as basic reference material for the effective planning and implementation of RCA projects. It is hoped that this study will be widely utilized for expanding Korea's participation in the RCA project and for establishing a future direction for RCA projects by the governments, industries, academic circles and research institutions

  1. In retrospect. 7th workshop RCA

    International Nuclear Information System (INIS)

    Knappik, Reinhard

    2013-01-01

    The 7th Workshop RCA with 27 lectures and 12 poster presentation took place on 10 and 11 June 2013 in Dresden-Rossendorf. The traditional German event brought over 90 participants together from Germany, Austria, France, Switzerland and the Netherlands. This time the workshop put forward a special subject for the first time ('Obstacles and pitfalls when characterising waste packages'). A remarkable range of contributions was presented, which demonstrated the diversity and the problems of this subject matter. Medium to low radioactive waste and their final disposal was discussed. Other topics were the upcoming approval of recycling materials according to paragraph 29 StrlSchV as well as those from NORM (Naturally Occurring Radioactive Materials) regarding radionuclide analytics, the range of matrices to be processed and the practical problems this causes. Although the radiological feature was the central focus, other material aspects were dealt with, above all the approval of recycling materials when nuclear power plants are dismantled, but also in research institutes, which is demanding more and more attention. The lectures by Jessica Riemer (GSI Darmstadt) on the topic 'Waste material management of a research centre with heavy ion accelerators' and Elvira Mesalic (TU Munich) on 'Determining the activity inventory of bituminized old wastes' as well as the poster by Sina Brockmann on the 'Locally resolved analysis or uranium species using a couple systems of CLSM and LIFS' were awarded prizes for being outstanding presentations. (orig.)

  2. Thirteenth meeting of representatives of RCA Member States

    International Nuclear Information System (INIS)

    1986-07-01

    The 13th Meeting of Member States of RCA (Regional Co-operative Agreement for Research, Development and Training Related to Nuclear Science and Technology) was held on 26 September 1984 in Vienna. This document constitutes the report of that meeting. It includes the list of participants, agenda, summary of discussions, and 1984 costing table. The Report of Recommendations for the meeting consisted of the Summary Report of the Sixth RCA Working Group Meeting held in Kalpakkam, India, 20-23 March 1984. This Summary Report dealt with such topics as RCA research projects (including nuclear techniques to improve legume and buffalo production, radiosterilization of medical supplies, maintenance of nuclear instruments, isotope applications in hydrology and sedimentology), progress of the RCA/UNDP Industrial Project, and future programmes and budget

  3. Strategy for effective participation in the RCA projects

    International Nuclear Information System (INIS)

    Kim, Kyoung Pyo; Lee, Jeong Kong

    1998-12-01

    This report attempts briefly to bring to light the current RCA programmes and to suggest ways of implementing future RCA programmes effectively. It is based principally upon the discussions and proposals made by the Member States of the RCA at the 20th Regular Meeting of Representative of RCA Member States at Taupo, New Zealand in April 1998 and at the 27th General Conference Meeting at Vienna, Austria in September 1998. The Asia-Pacific region is slowly but steadily growing in importance. With its vast human and natural resources, strategic geographical location and its scientific and technological backing, the countries in the region have tremendous potential to become the most dynamic, even leading nations of the world in the 21st century. During the past years, RCA has experienced great changes in its policies, strategies. These changes have also affected in the role of the Member States and the relation between the Agency and Member States. (author). 3 refs., 2 tabs., 1 fig

  4. LFI Radiometric Chain Assembly (RCA) data handling ``Rachel''

    Science.gov (United States)

    Malaspina, M.; Franceschi, E.; Battaglia, P.; Binko, P.; Butler, R. C.; D'Arcangelo, O.; Fogliani, S.; Frailis, M.; Franceschet, C.; Galeotta, S.; Gasparo, F.; Gregorio, A.; Lapolla, M.; Leonardi, R.; Maggio, G.; Mandolesi, N.; Manzato, P.; Maris, M.; Meharga, M.; Meinhold, P.; Morisset, N.; Pasian, F.; Perrotta, F.; Rohlfs, R.; Sandri, M.; Tomasi, M.; Türler, M.; Zacchei, A.; Zonca, A.

    2009-12-01

    Planck's Low Frequency Instrument is an array of 22 pseudo-correlation radiometers at 30, 44, and 70 GHz. Before integrating the overall array assembly, a first set of tests has been performed for each radiometer chain assembly (RCA), consisting of two radiometers. In this paper, we describe Rachel, a software application which has been purposely developed and used during the RCA test campaign to carry out both near-realtime on-line data analysis and data storage (in FITS format) of the raw output from the radiometric chains.

  5. LFI Radiometric Chain Assembly (RCA) data handling 'Rachel'

    International Nuclear Information System (INIS)

    Malaspina, M; Franceschi, E; Butler, R C; Mandolesi, N; Battaglia, P; Franceschet, C; Lapolla, M; Binko, P; Meharga, M; D'Arcangelo, O; Fogliani, S; Frailis, M; Galeotta, S; Gasparo, F; Maggio, G; Manzato, P; Maris, M; Gregorio, A; Leonardi, R; Meinhold, P

    2009-01-01

    Planck's Low Frequency Instrument is an array of 22 pseudo-correlation radiometers at 30, 44, and 70 GHz. Before integrating the overall array assembly, a first set of tests has been performed for each radiometer chain assembly (RCA), consisting of two radiometers. In this paper, we describe Rachel, a software application which has been purposely developed and used during the RCA test campaign to carry out both near-realtime on-line data analysis and data storage (in FITS format) of the raw output from the radiometric chains.

  6. Recognition factors of Ricinus communis agglutinin 1 (RCA(1)).

    Science.gov (United States)

    Wu, Albert M; Wu, June H; Singh, Tanuja; Lai, Li-Ju; Yang, Zhangung; Herp, Anthony

    2006-04-01

    Ricinus communis agglutinin (RCA1) is one of the most important applied lectins that has been widely used as a tool to study cell surfaces and to purify glycans. Although the carbohydrate specificity of RCA1 has been described, the information obtained was mainly focused on inhibition of simple Galbeta1-related oligosaccharides and simple clusters. Here, all possible recognition factors of RCA1 of glycan binding were examined by enzyme-linked lectinosorbent (ELLSA) and inhibition assays, using known mammalian Gal/GalNAc carbohydrate structural units and natural polyvalent glycans. Among the glycoproteins (gps) tested and expressed as 50% nanogram inhibition, the high-density polyvalent Galbeta1-4GlcNAc (II) glycotopes occurring in natural gps, such as Pneumococcus type 14 capsular polysaccharide which is composed of repeating poly II residues, resulted in 9.0 x 10(4), 1.5 x 10(5), 2.3 x 10(4) and 2.1 x 10(4)-fold higher affinities to RCA1 than the monomeric Gal, linear I/II and Tri-antennary-II (Tri-II). Of the ligands tested and expressed as nanomoles of 50% inhibition, Tri-II was the best, being about 2, 4, 25.6 and 33.3 times better inhibitor than Di-II, II, I (Galbeta1-3GlcNAc) and Gal, respectively. From the results of this study, it is concluded that: (a) Galbeta1-4GlcNAc and other Galbeta1-related oligosaccharides are essential for lectin binding and their polyvalent form in macromolecules should be the most important recognition factor for RCA1; (b) the combining site of RCA1 may be a groove type, recognizing Galbeta1-4GlcNAc (II) as the major binding site; (c) its combining size may be large enough to accommodate a tetrasaccharide of beta-anomeric Gal at the non-reducing end and most complementary to human blood group I Ma active trisaccharide (Galbeta1-4GlcNAcbeta1-6Gal) and lacto-N-neotetraose (Galbeta1-4GlcNAcbeta1-3Galbeta1-4Glc); (d) RCA1 has a preference for the beta-anomer of Gal oligosaccharides with a Galbeta1-4 linkage > Galbeta1-6 > or = Galbeta

  7. RCA activities in the Asian and Pacific Region

    International Nuclear Information System (INIS)

    Kobayashi, M.

    1984-01-01

    So-called ''RCA'' activities - practical work undertaken within the framework of a Regional Co-operative Agreement for Research, Development and Training related to Nuclear Science and Technology for the Asian and Pacific region - are widely regarded as an example of successful co-operative effort in the application of nuclear techniques at a regional level. Activities undertaken to promote the transfer of nuclear technology within the framework of the RCA cover a large spectrum of nuclear applications in agriculture and food production, medicine, study of the environment, industry, and physics. Fourteen projects are operational this year (1984)

  8. 'Los desengaños místicos' (1757) de fray José Alberto Gay

    OpenAIRE

    Mata-Induráin, C. (Carlos)

    2005-01-01

    Fray José Alberto Gay, tudelano, escribió varias obras literarias, de las que destaca su obra 'Los desengaños místicos', obra en verso publicada en 1757. Fray José Alberto Gay wrote several literary works; the most notably of them is his book 'Los desengaños místicos', book of verse published in 1757.

  9. In retrospect. 7th workshop RCA; Nachlese. 7. Workshop RCA. Conference report

    Energy Technology Data Exchange (ETDEWEB)

    Knappik, Reinhard [Verein fuer Kernverfahrenstechnik und Analytik Rossendorf e.V. (VKTA), Dresden-Rossendorf (Germany). Programmausschuss Workshop RCA

    2013-08-15

    The 7th Workshop RCA with 27 lectures and 12 poster presentation took place on 10 and 11 June 2013 in Dresden-Rossendorf. The traditional German event brought over 90 participants together from Germany, Austria, France, Switzerland and the Netherlands. This time the workshop put forward a special subject for the first time ('Obstacles and pitfalls when characterising waste packages'). A remarkable range of contributions was presented, which demonstrated the diversity and the problems of this subject matter. Medium to low radioactive waste and their final disposal was discussed. Other topics were the upcoming approval of recycling materials according to paragraph 29 StrlSchV as well as those from NORM (Naturally Occurring Radioactive Materials) regarding radionuclide analytics, the range of matrices to be processed and the practical problems this causes. Although the radiological feature was the central focus, other material aspects were dealt with, above all the approval of recycling materials when nuclear power plants are dismantled, but also in research institutes, which is demanding more and more attention. The lectures by Jessica Riemer (GSI Darmstadt) on the topic 'Waste material management of a research centre with heavy ion accelerators' and Elvira Mesalic (TU Munich) on 'Determining the activity inventory of bituminized old wastes' as well as the poster by Sina Brockmann on the 'Locally resolved analysis or uranium species using a couple systems of CLSM and LIFS' were awarded prizes for being outstanding presentations. (orig.)

  10. Influences and Evolution in the Political Thinking of Fray Servando Teresa de Mier

    Directory of Open Access Journals (Sweden)

    Rafael Diego-Fernández

    1998-07-01

    Full Text Available Fate had Fray Servando Teresa de Mier come to be side by side with the American delegates that participated in the Courts of Cádiz, after he passed from Portugal to Spain in 1808 to join the resistance against the Napoleonic invasion. This moment was determinant, and represented the trigger thar made him fight with all his strenght against the Spanish government, to defend the liberty and absolute independence of America. This is the cornerstone that allows us to undersand all Fray Servando's life and thought from that moment to his death. Considering that Mier became one of the most meaningful figures in the American independence movemnt, it is important to undersant clearly his motivations, his main ideas, his political beliefs, and his ideological models. True enough, from his conversion in 1808 to his full maturity, as representative of an independent Mexico, his thought evolved deeply, to the point that in many occasions he abandoned, without a doubt, ideas and convictions he had defended strongly at other times. All in all, the clarity of his goals and political stands' saved him from shipwrecking in a turbulent and agitated sea of wideranging political theories, originated in many points of Europe and America and struggling to impose themselves. After the deceiving experience in the Courts of Cádiz, Fray Servando left wishing to realize two dreams for all America: that of liberty and that of absolute -not relative, as some authors were beginning to suggest at that time- independence.

  11. Analyse der F-box Funktion von Rca1 in Drosophila melanogaster

    OpenAIRE

    Frank, Martina

    2015-01-01

    Rca1 ist ein wichtiger Inhibitor für die Ubiqutin-E3-Ligase APC/C mit dem Aktivatorproteine Fzr (Fizzy-related, ortholog zu Cdh1), vor allem in der G2-Phase des Zellzyklus, und ermöglicht die Akkumulati-on von Cyclinen für die darauffolgende Mitose. Embryonen, die die rca1-Allele rca1[2] und rca1[C1474] tragen, arretieren deshalb im Zellzyklus 16 und können nicht in die Mitose 16 eintreten. Durch Überexpression von Rca1 und Rca1 mit deletierter F-box (Rca1ΔF-box) konnte dieser Phänotyp komple...

  12. On editing the fifth stanza of El aire se serena by fray Luis

    Directory of Open Access Journals (Sweden)

    Aquilino Suárez Pallasá

    2011-12-01

    Full Text Available Although many scholars and editors of the ode «El aire se serena» by fray Luis de León have denied or questioned the authenticity of its fifth stanza, there now seems to be a general assent to its acceptance. The reason for such a change of heart has not to do with textual criticism proper, but with literature. The sources of the ode are said to justify it. In this paper a strictly critico-textual demonstration of the authenticity of stanza 5 is proposed, placing emphasis on the cause of the diffraction displayed in the erroneous lectiones of a segment of the stanza.

  13. José Bento Leite Ferreira de Melo, padre e político o Liberalismo moderado no extremo sul de Minas Gerais José Bento Leite Ferreira de Melo, priest and politic moderated Liberalism in the Minas southern

    Directory of Open Access Journals (Sweden)

    Isaías Pascoal

    2007-06-01

    Full Text Available Este artigo procura explicitar a trajetória política do Pe. José Bento Leite Ferreira de Mello. Após atuar em várias legislaturas como deputado, foi escolhido senador em 1834 pela Regência. José Bento foi, por mais de 20 anos, um dos mais importantes representantes políticos do sul de Minas. Sua ação foi ampla. Padre, vereador, jornalista, criador de Partido Liberal em várias vilas do sul de Minas, criador da Sociedade Defensora da Independência e Liberdade Nacional, deputado e, finalmente, senador. Tornou-se o mais expressivo articulador político dos interesses da elite sul-mineira na Corte, ao mesmo tempo em que a engajava nos desafios da luta pela constituição do Estado Nacional brasileiro na versão desejada pelos liberais moderados.This article intent to show the politic trajectory of Pe. José Bento Leite Ferreira de Mello. After acting in various legislatures as deputy, he was chosen senator in 1834 by the Regency. José Bento was, for over 20 years, one of the most important politic representative of the south of Minas. His action was wide. Priest, counselor, journalist, creator of Liberal Party in different villages of the south of Minas, creator of the Protector Society of Independency and National Freedom, deputy and, finally, senator. He became the most expressive politic articulator of the south-miner elite in the Corte, at the same time that he was engaging it in the challenges of the fight for the constitution of the Brazilian National State in the version desired by the moderated liberals.

  14. RCA/IAEA third external dosimetry intercomparison in East Asia

    International Nuclear Information System (INIS)

    Momose, T.; Yamamoto, H.; Cruz Suarez, R.

    2005-01-01

    Full text: Several intercomparison exercises were organized by the International Atomic Energy Agency (IAEA) on the determination of operational quantities at the regional or interregional basis. These exercises revealed significant differences in the approach, methods and assumptions, and consequently in the measurement results obtained by participating laboratories. In the East Asia region, the third phase of the Hp(10) intercomparison, organized within the frame of the Regional Cooperation Agreement (RCA) as a follow-up to previous exercises during 1990-92 and 1995-96, was completed mid-2004. The first phase grouped 25 laboratories from 16 member states, and 4 Secondary Standards Dosimetry Laboratories irradiated dosimeters in 6 different qualities for photon and beta radiations. In the second phase, 23 laboratories from 16 member states participated, and 3 Secondary Standards Dosimetry Laboratories provided irradiation in 5 different radiation qualities simulating workplace fields. The results of the second phase for the determination of operational quantities Hp(d) were satisfactory for all participating Member States, with marked improvement from the first phase; the laboratories demonstrated good performance in both quantities tested. These results underline the importance of such an intercomparison programme as a key element towards the harmonization of quantities and units on an international level. This paper presents the results of this RCA/IAEA intercomparison, and also the forthcoming RCA activities supporting intercomparison runs for the assessment of occupational exposure. Member states strongly recommend that the IAEA continue acting as a focal point for, inter alia, training in all forms, particularly in measurements and dosimetry techniques. This exercise also stressed the importance for the IAEA to take an active role in establishing a network of monitoring laboratories for radiation protection purposes, as it would provide for better information

  15. Results of the IAEA/RCA personal dosemeter intercomparison

    Energy Technology Data Exchange (ETDEWEB)

    Tsujimura, Norio; Momose, Takumaro; Hayashi, Naomi [Environment and Safety Division, Tokai Works, Japan Nuclear Cycle Development Inst., Tokai, Ibaraki (Japan)

    2000-06-01

    The intercomparison of personal dosemeters for photon was carried out between 1990 and 1996 as part of the IAEA/RCA 'strengthening of radiation protection infrastructure' project. Japan Nuclear Cycle Development Institute participated in the intercomparison as one of the in-house personal dosimetry service organizations in Japan and also served the host irradiating laboratory. This report summarizes the dose evaluation results obtained from the JNC-TLD badges in the past four intercomparison programs. In the latest intercomparison the evaluated doses agreed to the reference doses with an accuracy of 10%. (author)

  16. Tenth working group meeting of representatives of RCA Member States. Report

    International Nuclear Information System (INIS)

    1989-04-01

    The Tenth RCA (Regional Co-operative Agreement for Research, Development and Training Related to Nuclear Science and Technology) Working Group meeting of representatives of RCA Member States was held at the Chinese Academy of Agricultural Sciences, Beijing, between 11-14 April 1988. The report on the meeting consists of a presentation of the seven technical sessions which dealt with topics such as nuclear techniques in industry, agriculture and medicine, nuclear power and of the project reports under RCA

  17. Functional analysis of the cell cycle regulator Rca1 in Drosophila melanogaster

    OpenAIRE

    Zielke, Norman

    2007-01-01

    Tight regulation of APC/C activity is essential for cell cycle progression. An important class of negative APC/C regulators are the Rca1/Emi1 family proteins. All members of the Rca1/Emi1 family share a conserved zinc binding region (ZBR) which is essential for their inhibitory activity. The Rca1/Emi1 proteins belong to the class of F-box proteins that are known to act as substrate recognition subunits in SCF-E3-ligase complexes. Emi1 and Rca1 interact in vitro with members of the Skp family ...

  18. Report of the IAEA/RCA-NDT education project

    Energy Technology Data Exchange (ETDEWEB)

    Ooka, Kiichi; Terada, Kunio; Ohtani, Kiyoshi; Niwa, Noboru

    1988-11-01

    The Japan Non-Destructive Test (NDT) Association has been carried out an NDT technical education project with support from IAEA. Phase I of the project was successfully completed last year. The present report briefly outlines the second five-year plan (Phase II) to be carried out under the project. The project was first established in 1981 after receiving a request from IAEA to provide NDT education for participants from the RCA countries (13 countries in Asian and Pacific area). Phase I was mainly designed to provide lectures on NDT techniques. Prior to the start of Phase II, the International Education Subcommittee was established in December 1986 to take the leadership in carrying out Phase II of the project. In addition, the NDT Expert Working Group (formally called Advisory Group) has been installed which consists of representative from Japan. Australia India and Singapore. The Group held nine meetings during Phase I. Three lecture meetings at Singapore and another three at Tokyo were held to provide education according to a plan developed by the Group. It has been decided that Japan be support the lecture meetings to be held during Phase II. To conduct such meetings, a group comprising all of the National Coordinators from the RCA countries was set up to replace the Working Group. The National Coordinator Conference was held four times since its establishment. (N.K.).

  19. Report of the IAEA/RCA-NDT education project

    International Nuclear Information System (INIS)

    Ooka, Kiichi; Terada, Kunio; Ohtani, Kiyoshi; Niwa, Noboru.

    1988-01-01

    The Japan Non-Destructive Test (NDT) Association has been carried out an NDT technical education project with support from IAEA. Phase I of the project was successfully completed last year. The present report briefly outlines the second five-year plan (Phase II) to be carried out under the project. The project was first established in 1981 after receiving a request from IAEA to provide NDT education for participants from the RCA countries (13 countries in Asian and Pacific area). Phase I was mainly designed to provide lectures on NDT techniques. Prior to the start of Phase II, the International Education Subcommittee was established in December 1986 to take the leadership in carrying out Phase II of the project. In addition, the NDT Expert Working Group (formally called Advisory Group) has been installed which consists of representative from Japan. Australia India and Singapore. The Group held nine meetings during Phase I. Three lecture meetings at Singapore and another three at Tokyo were held to provide education according to a plan developed by the Group. It has been decided that Japan be support the lecture meetings to be held during Phase II. To conduct such meetings, a group comprising all of the National Coordinators from the RCA countries was set up to replace the Working Group. The National Coordinator Conference was held four times since its establishment. (N.K.)

  20. Un nuevo plagio de Fray Prudencio de Sandoval : El Antijovio de Quesada saqueado

    Directory of Open Access Journals (Sweden)

    Darío Achury Valenzuela

    1967-11-01

    Full Text Available Ruy Diaz fue el nombre de pila de fray Prudencio de Sandoval sobre cuya limpieza de progenie no han logrado ponerse aún de acuerdo sus biógrafos. Lo cierto es que nació en 1551 o 1652, en Valladolid y murió siendo Obispo de Pamplona, en 1620. De mucho valimiento le sirvió en su vida la no muy desinteresada, aunque sí muy positiva protección de su lejano cognado don Francisco Gómez de Sandoval y Rojas, futuro Duque de Lerma, ya que de humilde fraile recoleto en el Monasterio de Santa María la Real de Nájera fue enaltecido a la dignidad episcopal, con sede sucesiva en las Diócesis de Cuenca, Tuy y Pamplona.

  1. Predicting of the compressive strength of RCA concrete

    Directory of Open Access Journals (Sweden)

    Jaskulski Roman

    2017-01-01

    Full Text Available The paper presents the results of predicting the strength of 61 concretes made with the use of recycled concrete aggregate (RCA. Five models in the form of first-order polynomials containing two to six variables characterizing the composition of the mixture were formulated for this purpose. Factors for unknowns were selected using linear regression in two variants: with and without additional coefficient. For each model, the average absolute error of the concrete strength estimation was determined. Because of the various consequences of underestimation and overestimation of the results, the analysis of models quality was carried out with the distinction of the two cases. The results indicate that the key to improving the quality of models is to take into account the quality of the aggregate expressed by the ACV parameter. Better match results were also obtained for models with more variables and the additional coefficient.

  2. The 2015 Resuscitation Council of Asia (RCA) guidelines on adult basic life support for lay rescuers.

    Science.gov (United States)

    Chung, Sung Phil; Sakamoto, Tetsuya; Lim, Swee Han; Ma, Mathew Huei-Ming; Wang, Tzong-Luen; Lavapie, Francis; Krisanarungson, Sopon; Nonogi, Hiroshi; Hwang, Sung Oh

    2016-08-01

    This paper introduces adult basic life support (BLS) guidelines for lay rescuers of the resuscitation council of Asia (RCA) developed for the first time. The RCA BLS guidelines for lay rescuers have been established by expert consensus among BLS Guidelines Taskforce of the RCA on the basis of the 2015 International Consensus on Cardiopulmonary Resuscitation (CPR) and Emergency Cardiovascular Care Science with Treatment Recommendations. The RCA recommends compression-only CPR for lay rescuers and emphasizes high-quality CPR with chest compression depth of approximately 5cm and chest compression rate of 100-120min(-1). Role of emergency medical dispatchers in helping lay rescuers recognize cardiac arrest and perform CPR is also emphasized. The RCA guidelines will contribute to help Asian countries establish and implement their own CPR guidelines in the context of their domestic circumstances. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  3. Potential risks of the residue from Samarco's mine dam burst (Bento Rodrigues, Brazil).

    Science.gov (United States)

    Segura, Fabiana Roberta; Nunes, Emilene Arusievicz; Paniz, Fernanda Pollo; Paulelli, Ana Carolina Cavalheiro; Rodrigues, Gabriela Braga; Braga, Gilberto Úbida Leite; Dos Reis Pedreira Filho, Walter; Barbosa, Fernando; Cerchiaro, Giselle; Silva, Fábio Ferreira; Batista, Bruno Lemos

    2016-11-01

    On November 5th, 2015, Samarco's iron mine dam - called Fundão - spilled 50-60 million m 3 of mud into Gualaxo do Norte, a river that belongs to Rio Doce Basin. Approximately 15 km 2 were flooded along the rivers Gualaxo do Norte, Carmo and Doce, reaching the Atlantic Ocean on November 22nd, 2015. Six days after, our group collected mud, soil and water samples in Bento Rodrigues (Minas Gerais, Brazil), which was the first impacted area. Overall, the results, water samples - potable and surface water from river - presented chemical elements concentration according to Brazilian environmental legislations, except silver concentration in surface water that ranged from 1.5 to 1087 μg L -1 . In addition, water mud-containing presented Fe and Mn concentrations approximately 4-fold higher than the maximum limit for water bodies quality assessment, according to Brazilian laws. Mud particle size ranged from 1 to 200 μm. SEM-EDS spot provided us some semi quantitative data. Leaching/extraction tests suggested that Ba, Pb, As, Sr, Fe, Mn and Al have high potential mobilization from mud to water. Low microbial diversity in mud samples compared to background soil samples. Toxicological bioassays (HepG2 and Allium cepa) indicated potential risks of cytotoxicity and DNA damage in mud and soil samples used in both assays. The present study provides preliminary information aiming to collaborate to the development of future works for monitoring and risk assessment. Copyright © 2016 Elsevier Ltd. All rights reserved.

  4. 19. working group meeting of representatives of RCA member States. Report

    International Nuclear Information System (INIS)

    1997-03-01

    The 19. RCA Working Group Meeting was hosted by the Myanmar Atomic Energy Committee in Yangon from 10-14 March 1997. The meeting marked the 25. anniversary of the RCA which commenced in 1972. It was attended by 29 delegates from 15 visiting RCA Member States, 15 participants from Myanmar and 4 from the IAEA. The report contains the statements of the following countries: Australia, Bangladesh, China, India, Indonesia, Japan, Republic of Korea, Malaysia, Mongolia, Myanmar, New Zealand, Pakistan, Philippines, Singapore, Sri Lanka, Thailand, and Viet Nam. Tabs

  5. 19. working group meeting of representatives of RCA member States. Report

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-03-01

    The 19. RCA Working Group Meeting was hosted by the Myanmar Atomic Energy Committee in Yangon from 10-14 March 1997. The meeting marked the 25. anniversary of the RCA which commenced in 1972. It was attended by 29 delegates from 15 visiting RCA Member States, 15 participants from Myanmar and 4 from the IAEA. The report contains the statements of the following countries: Australia, Bangladesh, China, India, Indonesia, Japan, Republic of Korea, Malaysia, Mongolia, Myanmar, New Zealand, Pakistan, Philippines, Singapore, Sri Lanka, Thailand, and Viet Nam. Tabs.

  6. Analysis of Rca1 function at the G1-S transition in Drosophila melanogaster

    OpenAIRE

    Querings, Silvia

    2008-01-01

    Tight control of APC/C-Cdh1Fzr activity is essential for progression through mitosis and establishment of the G1 phase. Rca1 is a nuclear protein that inhibits the APC/C-Cdh1Fzr complex during G2 to allow cyclin accumulation and subsequent entry into mitosis. In this thesis, a localisation study of Rca1 was performed revealing that a nuclear localisation sequence (NLS) and other domains in the protein mediate efficient nuclear accumulation. Besides its function in G2, Rca1 expression can prom...

  7. The fourth UNDP/RCA/IAEA/meeting of national co-ordinators for radiation technology. Report

    International Nuclear Information System (INIS)

    1996-01-01

    The objectives of the Meeting were to provide information for the Terminal Report of the joint UNDP/RCA/IAEA project RAS/92/073 and to look into future activities under the Radiation Technology project. The main achievements of this Meeting are: The Meeting reviewed the implementation of all radiation technology sub-projects and agreed that all of them were successful but not yet equally developed among RCA Member States. The Meeting recommended to have three projects carried out in the form of Co-ordinated Research Programs and requested the IAEA to find new ways to implement the organized in RCA Member States to carry these CRPs out. Figs, tabs

  8. Propaganda and Philanthropy: The Institute Bento da Rocha Cabral, the Lisbon Site of Biochemistry (1925-1953).

    Science.gov (United States)

    Carneiro, Ana; Amaral, Isabel

    2015-05-01

    This paper focuses on the internal organization and dynamics of the Institute Bento da Rocha Cabral (IRC) in Lisbon, a privately-funded institution devoted to biomedical research, from the particular vantage point of its laboratory of biochemistry; in particular, the process through which the institution turned from medically-related to chemically-related research in the period spanning from 1925 to 1953. The history of the IRC raises interesting questions regarding the social politics of science as it materialized the desire of leading physicians of the Faculty of Medicine of Lisbon to create proper physical facilities for medically-related scientific research. We argue that the process which led to the creation of the IRC coincided with the gradual professional and political ascendance of physicians in Portuguese society initiated in the late nineteenth century, and is closely associated with Portuguese republicanism and the process of Lisbon becoming the scientific capital.

  9. Os sobrenomes dos alunos do IFRS campus Bento Gonçalves: um estudo onomástico

    Directory of Open Access Journals (Sweden)

    Kleber Eckert

    2016-03-01

    Full Text Available O presente artigo propõe-se a fazer um estudo antroponímico a partir dos sobrenomes do corpo discente do IFRS campus Bento Gonçalves. Para tanto, fez-se um levantamento dos 20 sobrenomes que ocorrem com mais frequência, os quais foram divididos por origem étnica e analisados histórica e etimologicamente, levando-se em conta também os usos desses sobrenomes no Rio Grande do Sul e no Brasil. Além de discutir questões inerentes à onomástica e, dentre dela, a antroponímia, chegou-se à conclusão de que existe uma estreita relação entre os sobrenomes dos alunos matriculados no campus e a região onde ele está localizado, sobretudo quanto à origem étnico-linguística desses sobrenomes.

  10. Presencia de Spiroplasma penaei en plancton, bentos y fauna acompañante en fincas camaroneras de Colombia

    Directory of Open Access Journals (Sweden)

    José Altamiranda M.

    2011-05-01

    Full Text Available Objetivo. Determinar la presencia de Spiroplasma penaei en el plancton, bentos y fauna acompañante en 2 fincas comerciales de camarones. Materiales y métodos. Fueron colectadas 200 muestras para identificación de lesiones características de Spiroplasma, a través de la técnica de histología, mientras que para la técnica de PCR se tomaron 326 muestras de plancton, bentos y fauna acompañante. Las muestras colectadas fueron preservadas en tubos estériles con etanol al 95% para análisis de PCR y en solución Davidson para análisis histológicos. Resultados. En los muestreos realizados en las dos fincas camaroneras fue detectada la presencia de Spiroplasma en una muestra de un representante de los dípteros (mosca de agua a través de la técnica de PCR en tiempo real, el cual arrojo una Tm=84, similar a la del control positivo de Spiroplasma utilizado. Esta muestra fue secuenciada y comparada con secuencias de bacterias almacenadas en el banco de datos GenBank usando el algoritmo BLAST, encontrando 100% de homología con un fragmento de los genes ribosomales 16S de la bacteria Spiroplasma penaei. Conclusiones. La mosca de agua es portadora de Spiroplasma penaei, sin embargo no se puede afirmar que este organismo sea el transmisor de la infección, por lo que se recomienda realizar ensayos de tipo experimental con moscas de agua infectadas con Spiroplasma penaei, en camarones libres de patógenos, para evaluar si en realidad es el vector de infección.

  11. Rca1 inhibits APC-Cdh1(Fzr) and is required to prevent cyclin degradation in G2.

    Science.gov (United States)

    Grosskortenhaus, Ruth; Sprenger, Frank

    2002-01-01

    We demonstrate that Rca1 is an essential inhibitor of the anaphase-promoting complex/cyclosome (APC) in Drosophila. APC activity is restricted to mitotic stages and G1 by its activators Cdc20-Fizzy (Cdc20(Fzy)) and Cdh1-Fizzy-related (Cdh1(Fzr)), respectively. In rca1 mutants, cyclins are degraded prematurely in G2 by APC-Cdh1(Fzr)-dependent proteolysis, and cells fail to execute mitosis. Overexpression of Cdh1(Fzr) mimics the rca1 phenotype, and coexpression of Rca1 blocks this Cdh1(Fzr) function. We show that Rca1 and Cdh1(Fzr) are in a complex that also includes the APC component Cdc27. Previous studies have shown that phosphorylation of Cdh1 prevents its interaction with the APC. Our data reveal a different mode of APC regulation by Rca1 at the G2 stage, when low Cdk activity is unable to inhibit Cdh1(Fzr) interaction.

  12. Mutations in RCA1 and AFG3 inhibit F1-ATPase assembly in Saccharomyces cerevisiae.

    Science.gov (United States)

    Paul, M F; Tzagoloff, A

    1995-10-02

    The RCA1 (YTA12) and AFG3 (YTA10) genes of Saccharomyces cerevisiae code for homologous mitochondrial proteins that belong to the recently described AAA protein-family [Kunau et al. (1993) Biochimie 75,209-224]. Mutations in either gene have been shown to induce a respiratory defect. In the case of rca1 mutants this phenotype has been ascribed to defective assembly of cytochrome oxidase and ubiquinol-cytochrome c reductase. In the present study we show that the respiratory defect of afg3 mutants, like that of rca1 mutants, is also caused by an arrest in assembly of cytochrome oxidase and ubiquinol-cytochrome c reductase. In addition to the absence of the respiratory complexes, rca1 and afg3 mutants exhibit reduced mitochondrial ATPase activity. As a first step to an understanding of the biochemical basis for the ATPase defect we have examined the assembly of the F1 and F0 constituents of the ATPase complex. We present evidence that the ATPase lesion stems at least in part from the failure of rca1 and afg3 mutants to assemble F1. Although the mutants also display lower steady-state concentrations of some F0 subunits, this could be a secondary effect of defective F1 assembly.

  13. Sensitive magnetic biodetection using magnetic multi-core nanoparticles and RCA coils

    Energy Technology Data Exchange (ETDEWEB)

    Ahrentorp, Fredrik; Blomgren, Jakob; Jonasson, Christian; Sarwe, Anna [Acreo Swedish ICT AB, Arvid Hedvalls Backe 4, Göteborg (Sweden); Sepehri, Sobhan; Eriksson, Emil; Kalaboukhov, Alexei; Jesorka, Aldo; Winkler, Dag [Department of Microtechnology and Nanoscience – MC2, Chalmers University of Technology, Göteborg (Sweden); Schneiderman, Justin F. [Institute of Neuroscience and Physiology, University of Gothenburg and MedTech West, Göteborg (Sweden); Nilsson, Mats [Science for Life Laboratory, Department of Biochemistry and Biophysics, Stockholm University, Stockholm (Sweden); Albert, Jan [Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm (Sweden); Department of Clinical Microbiology, Karolinska University Hospital, Stockholm (Sweden); Zardán Gómez de la Torre, Teresa; Strømme, Maria [Uppsala University, Uppsala (Sweden); Johansson, Christer, E-mail: christer.johansson@acreo.se [Acreo Swedish ICT AB, Arvid Hedvalls Backe 4, Göteborg (Sweden)

    2017-04-01

    We use functionalized iron oxide magnetic multi-core particles of 100 nm in size (hydrodynamic particle diameter) and AC susceptometry (ACS) methods to measure the binding reactions between the magnetic nanoparticles (MNPs) and bio-analyte products produced from DNA segments using the rolling circle amplification (RCA) method. We use sensitive induction detection techniques in order to measure the ACS response. The DNA is amplified via RCA to generate RCA coils with a specific size that is dependent on the amplification time. After about 75 min of amplification we obtain an average RCA coil diameter of about 1 µm. We determine a theoretical limit of detection (LOD) in the range of 11 attomole (corresponding to an analyte concentration of 55 fM for a sample volume of 200 µL) from the ACS dynamic response after the MNPs have bound to the RCA coils and the measured ACS readout noise. We also discuss further possible improvements of the LOD. - Highlights: • Biosensing using Brownian relaxation of functionalized magnetic nanoparticles. • Rolling circle amplification and magnetic nanoparticles enables biosensing. • Theoretical limit of detection estimated from the signal noise gives about 55 fM.

  14. Molecular dissection of the APC/C inhibitor Rca1 shows a novel F-box-dependent function

    OpenAIRE

    Zielke, Norman; Querings, Silvia; Grosskortenhaus, Ruth; Reis, Tânia; Sprenger, Frank

    2006-01-01

    Rca1 (regulator of Cyclin A)/Emi (early mitotic inhibitor) proteins are essential inhibitors of the anaphase-promoting complex/cyclosome (APC/C). In Drosophila, Rca1 is required during G2 to prevent premature cyclin degradation by the Fizzy-related (Fzr)-dependent APC/C activity. Here, we present a structure and function analysis of Rca1 showing that a carboxy-terminal fragment is sufficient for APC/C inhibition. Rca1/Emi proteins contain a conserved F-box and interact with components of the ...

  15. Molecular dissection of the APC/C inhibitor Rca1 shows a novel F-box-dependent function.

    Science.gov (United States)

    Zielke, Norman; Querings, Silvia; Grosskortenhaus, Ruth; Reis, Tânia; Sprenger, Frank

    2006-12-01

    Rca1 (regulator of Cyclin A)/Emi (early mitotic inhibitor) proteins are essential inhibitors of the anaphase-promoting complex/cyclosome (APC/C). In Drosophila, Rca1 is required during G2 to prevent premature cyclin degradation by the Fizzy-related (Fzr)-dependent APC/C activity. Here, we present a structure and function analysis of Rca1 showing that a carboxy-terminal fragment is sufficient for APC/C inhibition. Rca1/Emi proteins contain a conserved F-box and interact with components of the Skp-Cullin-F-box (SCF) complex. So far, no function has been ascribed to this domain. We find that the F-box of Rca1 is dispensable for APC/C-Fzr inhibition during G2. Nevertheless, we show that Rca1 has an additional function at the G1-S transition, which requires the F-box. Overexpression of Rca1 accelerates the G1-S transition in an F-box-dependent manner. Conversely, S-phase entry is delayed in cells in which endogenous Rca1 is replaced by a transgene lacking the F-box. We propose that Rca1 acts as an F-box protein in an as yet uncharacterized SCF complex, which promotes S-phase entry.

  16. Vergel de perfectísimas flores. Las dominicas valencianas de Carcaixent según fray José Agramunt

    Directory of Open Access Journals (Sweden)

    Emilio Callado Estela

    2016-12-01

    Full Text Available El presente trabajo pretende rescatar del olvido una de los conventos dominicanos más desconocidos del ámbito valenciano. En concreto, el de Corpus Christi de la localidad de Carcaixent, en la ribera del rio Xúquer. Fundación tardobarroca ésta, erigida en 1654, objeto ya en el siglo XVIII del interés histórico de uno de sus primeros confesores. Hablamos de fray José Agramunt, autor del inédito Parayso de Dios. Idea del religiosíssimo monasterio de señoras dominicas de la real villa de Carcaxente, analizado en las siguientes páginas en el marco de la vida y producción literaria del citado religioso. In this present work, we aim to recover one of the forgotten dominican convents from Valencia. More specifically, the convent of the Corpus Christi located in Carcaixent, on the banks of the River Xúquer. This late Baroque convent was built in 1654. By the eighteenth century, one of his confessors had already made clear its historical interest. We are referring to fray José Agramunt, the author of the unpublished work, Parayso de Dios: Idea del Religiosíssimo Monasterio de Señoras Dominicas de la Real Villa de Carcaxente, analysis in the following pages the life and literal works of the aforementioned religious.

  17. Trauma ocular aberto: características de casos atendidos no complexo Hospitalar Padre Bento de Guarulhos Ocular open trauma: characteristics of admitted cases at the Padre Bento Hospital of Guarulhos, SP

    Directory of Open Access Journals (Sweden)

    Mônica Weyll

    2005-08-01

    Full Text Available OBJETIVOS: Estudos em centros oftalmológicos têm sido realizados com a finalidade de decifrar as principais causas e características epidemiológicas do trauma ocular. Nestes estudos observa-se uma variação na distribuição epidemiológica do trauma ocular e uma carência na educação e conscientização da sociedade sobre as medidas preventivas no Brasil. O objetivo deste estudo é identificar a incidência do trauma ocular aberto no serviço de emergência do Complexo Hospitalar Padre Bento de Guarulhos. MÉTODOS: Este é um estudo transversal descritivo realizado no período de setembro de 2003 a abril de 2004. Foram incluídos no trabalho, todos os pacientes atendidos no PS de Oftalmologia com diagnóstico de trauma ocular aberto. Foram obtidos alguns dados sobre o paciente: idade, sexo, profissão, uso de equipamento de trabalho, uso de óculos, uso de cinto de segurança, tipo de acidente, olho acometido, tempo decorrido até o primeiro atendimento oftalmológico e qual o primeiro local de atendimento. RESULTADOS: A média de idade foi de 34,35 anos, sendo o sexo masculino o mais acometido (87%. O acidente automobilístico foi o mais freqüente. A baixa acuidade visual foi importante fator de procura precoce pelo serviço de emergência, sendo que 92,3% dos pacientes o fizeram em menos de 12 horas de decorrido o trauma. CONCLUSÃO: O trauma penetrante corneano foi o tipo de lesão ocular mais observado. Os pacientes mais acometidos são adultos jovens, do sexo masculino, vítimas de acidente automobilístico, sendo o olho direito o mais acometido. A complicação imediata mais observada foi a baixa acuidade visual.PURPOSE: This study tends to identify the incidence of ocular open trauma at the emergency service of the "Complexo Hospitalar Padre Bento of Guarulhos, SP". METHODS: It is a descriptive transversal study performed in a period of four months at the "Complexo Hospitalar Padre Bento". All patients admitted at the emergency

  18. RCA/IAEA third external dosimetry intercomparisons in East Asia region

    International Nuclear Information System (INIS)

    Yamamoto, H.; Yoshizawa, M.; Murakami, H.; Momose, T.; Tsujimura, N.; Kanai, K.; Cruz-Suarez, R.

    2007-01-01

    Several intercomparison exercises were organised by the International Atomic Energy Agency (IAEA) on the determination of operational quantities at the regional or inter-regional basis. In East Asia region, a third phase of the intercomparison finished in mid 2004. It was organised within the frame of the Regional Cooperation Agreement (RCA) as a follow-up to previous exercises carried out during 1990-1992 and 1995-1996. The results of this intercomparison for the determination of operational quantities were satisfactory for all Member States. The laboratories demonstrated a good performance in quantities tested. The purpose of this paper is to present the results of the RCA/IAEA intercomparison and the future of RCA activities in support of assessment of occupational exposure by organising intercomparison runs. (authors)

  19. Dynamic range studies of the RCA streak tube in the LLL streak camera

    International Nuclear Information System (INIS)

    Thomas, S.W.; Phillips, G.E.

    1979-01-01

    As indicated by tests on several cameras, the dynamic range of the Lawrence Livermore Laboratory streak-camera system appears to be about two orders of magnitude greater than those reported for other systems for 10- to 200-ps pulses. The lack of a fine mesh grid in the RCA streak tube used in these cameras probably contributes to a lower system dynamic noise and therefore raises the dynamic range. A developmental tube with a mesh grid was tested and supports this conjecture. Order-of-magnitude variations in input slit width do not affect the spot size on the phosphor or the dynamic range of the RCA tube. (author)

  20. The economic and social significance of RCA regional co-operative projects

    International Nuclear Information System (INIS)

    Fowler, E.E.

    1979-01-01

    The regional Co-operative Agreement for Research, Development and Training Related to Nuclear Science and Technology (RCA) is an established and valuable instrument between the International Atomic Energy Agency (IAEA) and Member States in South Asia, Southeast Asia and the Pacific or Far East for assisting in the transfer of modern technology to areas having economic and social importance to the region. The purpose of this review is to identify on-going or planned work which is designed to help achieve this goal. Currently approved RCA Regional Co-operative Research Projects are listed

  1. Essence of Daylight in the Cistercian Monastic Church of S. Bento de Cástris, Évora, Portugal

    Science.gov (United States)

    Martins, Ana M. T.; Carlos, Jorge S.

    2017-10-01

    Natural light in the Cistercian churches is closely linked not only with the liturgical requirements at the “officium” but also with the canonical hours based on the "ora et labora" dictated by the Rule of St. Benedict. The Cistercian architecture, in its beginnings (12th century forward) is characterized by austerity, simplicity and the play of light and shadow that gives value to the monastic architectural space itself, making it perfect for a contemplative experience. In the Cistercian Monastery the church is the central piece of the monastic building. Nave, transept and apse are the main architectural components to which is added the choir. This paper contextualizes the importance and close connections of natural light, within the Cistercian Monasteries architecture. Thus the essence of daylight is analysed within the Church of the Monastery of S. Bento de Cástris, in Évora, Portugal. This former Monastery (13th - 19th centuries) includes the church, at the south-eastern corner which has not only a high choir, but also a low lateral choir (within the presbytery). Its unchanged exterior walls are made of solid masonry. Although the function of the walls is primarily structural, the windows allow the daylight to penetrate the space of the church. The church has two external façades facing northeast and southeast. The combined orientation effect of the church’s main axis and the sun trajectory determines how the sunlight reaches the interior of this architectural structure. This study presents the qualitative and quantitative analysis of the luminous environment in the church of S. Bento de Cástris, being the first based on the authors’ perception of the effect of the daylight within the different areas of the enclosed space. The appreciation of the spatial experiences was supported by quantitative daylight simulations that were conducted in selected areas within the space. With this paper is intended to contribute to the debate about the specificity

  2. The effect of recycled concrete aggregate properties on the bond strength between RCA concrete and steel reinforcement

    International Nuclear Information System (INIS)

    Butler, L.; West, J.S.; Tighe, S.L.

    2011-01-01

    The purpose of this study was to investigate the influence that replacing natural coarse aggregate with recycled concrete aggregate (RCA) has on concrete bond strength with reinforcing steel. Two sources of RCA were used along with one natural aggregate source. Numerous aggregate properties were measured for all aggregate sources. Two types of concrete mixture proportions were developed replacing 100% of the natural aggregate with RCA. The first type maintained the same water-cement ratios while the second type was designed to achieve the same compressive strengths. Beam-end specimens were tested to determine the relative bond strength of RCA and natural aggregate concrete. On average, natural aggregate concrete specimens had bond strengths that were 9 to 19% higher than the equivalent RCA specimens. Bond strength and the aggregate crushing value seemed to correlate well for all concrete types.

  3. 45 CFR 400.66 - Eligibility and payment levels in a publicly-administered RCA program.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 2 2010-10-01 2010-10-01 false Eligibility and payment levels in a publicly... REFUGEE RESETTLEMENT PROGRAM Refugee Cash Assistance § 400.66 Eligibility and payment levels in a publicly-administered RCA program. (a) In administering a publicly-administered refugee cash assistance program, the...

  4. Design rules for RCA self-aligned silicon-gate CMOS/SOS process

    Science.gov (United States)

    1977-01-01

    The CMOS/SOS design rules prepared by the RCA Solid State Technology Center (SSTC) are described. These rules specify the spacing and width requirements for each of the six design levels, the seventh level being used to define openings in the passivation level. An associated report, entitled Silicon-Gate CMOS/SOS Processing, provides further insight into the usage of these rules.

  5. Operation EUFOR TCHAD/RCA and the European Union’s Common Security and Defense Policy

    Science.gov (United States)

    2010-10-01

    Lessons from EUFOR Tchad/RCA, March 2010. 152. For a more detailed description of the EU Battlegroups, see Gustav Lindstrom , “Enter the EU Battlegroups...Major General Gregg F. Martin Commandant ***** STRATEGIC STUDIES INSTITUTE Director Professor Douglas C. Lovelace, Jr. Director of Research Dr. Antulio J

  6. Descriptive analysis of factors that influence economical results in the furniture cluster of Bento Gonçalves

    Directory of Open Access Journals (Sweden)

    Miguel Afonso Sellitto

    2014-12-01

    Full Text Available The purpose of this article is to analyze factors that can influence the competitiveness of companies in the furniture cluster of Bento Gonçalves, Rio Grande do Sul. By a literature review, we identify four factors that can influence competition in clusters: the region's productivity, innovation, relationship with suppliers, and cooperation between companies. The research method is the single case study. The research techniques are the review of specific bibliographic and documentation of the studied cluster, and interviews with experts of the cluster. The main findings are: the cluster has high productivity, mainly by hi-tech machinery employed by the main companies; innovation is permanent and motivated by the imposition to medium and short companies of business goals by the main companies; the relationship with suppliers is problematic regarding the large-scale vendors by the lack of the practice of collective purchases in the area; and cooperation between enterprises is small, by the culture of the region that don´t appreciate depending on resources available outside the companies. Such factors can contribute to produce hypotheses for further research.

  7. Immunomodulatory response of mice splenocytes induced by RcaL, a lectin isolated from cobia fish (Rachycentron canadum) serum.

    Science.gov (United States)

    Coriolano, Marília Cavalcanti; Silva, Cynarha Daysy Cardoso da; Melo, Cristiane Moutinho Lagos de; Bezerra, Ranilson de Souza; Santos, Athiê Jorge Guerra; Pereira, Valéria Rêgo Alves; Coelho, Luana Cassandra Breitenbach Barroso

    2012-11-01

    This work reports the isolation of a serum lectin from cobia fish (Rachycentron canadum) named RcaL. Immunomodulatory activity on mice splenocyte experimental cultures through cytotoxic assays and cytokine production were also performed. RcaL was obtained through precipitation with ammonium sulphate and affinity chromatography on a Concanavalin A-Sepharose 4B column. The ammonium sulphate fraction F3 showed the highest specific hemagglutinating activity and was applied to affinity chromatography. The lectin was eluted with methyl-α-D-mannopyranoside. RcaL showed highest affinity for methyl-α-D-mannopyranoside and D-mannose; eluted fractions of RcaL agglutinated rabbit erythrocytes (titre, 128(-1)) retained 66 % of chromatographed lectin activity, and the obtained purification factor was 1.14. Under reducing conditions, a polypeptide band of 19.2 kDa was revealed in sodium dodecyl sulphate polyacrylamide gel electrophoresis (PAGE). PAGE confirmed RcaL as an acidic protein revealed in a single band. Cytotoxic and immunomodulatory assays with RcaL in mice splenocyte cultures showed that the lectin was not cytotoxic and induced higher interferon gamma and nitric oxide production in splenocyte cultures. Purified RcaL induced preferential Th1 response, suggesting that it acts as an immunomodulatory compound.

  8. RCA and its regional office for cooperative activities in the applications of nuclear techniques in Asia and the Pacific

    International Nuclear Information System (INIS)

    Lee, Jae-Sol

    2008-01-01

    The Regional Cooperative Agreement for Research, Development and Training Related to Nuclear Science and Technology (RCA) is an intergovernmental agreement among 17 Member States of the International Atomic Energy Agency (IAEA), in South Asia, South East Asia, Far East and the Pacific, established for promoting regional cooperation in the peaceful uses of nuclear science and technology. Established in 1972, the RCA is a unique development within the technical cooperation framework coordinated by IAEA is support of the regional cooperation in the applications of nuclear technology to the benefit of its Member States. It has a well established network of scientists trained in the use of nuclear technologies in the agricultural, medical, industrial, and environmental sectors, with a good potentiality to use its regional technical and scientific resources to contribute to the solution of some of the significant problems in the region. The achievements recorded in the several decades of RCA history cover a wide spectrum of areas and these achievements have been published a Success Stories. Having recognized a need to enhance ownership of the region, the RCA Member States had wished to establish its Regional Office (RCARO). The Regional Office which is hosted by the Government of Republic of Korea was established in 2002. Located in Daejeon, the RCARO has been active in its endeavors toward increasing visibility of the RCA and establishing cooperative partnership between RCA and other international organizations. The RCARO has also played a key role in successfully implementing an RCA Project on Post-Tsunami Environment Impact Assessment in partnership with UNDP (Republic of Korea) with the participation of 14 RCA Member States. A number of projects for capacity building in the region are also being implemented by RCARO, mostly by providing training opportunities for young professionals in the region. The RCA community welcomes any contacts from potential end-users or

  9. Mechanical properties of concrete containing recycled concrete aggregate (RCA) and ceramic waste as coarse aggregate replacement

    Science.gov (United States)

    Khalid, Faisal Sheikh; Azmi, Nurul Bazilah; Sumandi, Khairul Azwa Syafiq Mohd; Mazenan, Puteri Natasya

    2017-10-01

    Many construction and development activities today consume large amounts of concrete. The amount of construction waste is also increasing because of the demolition process. Much of this waste can be recycled to produce new products and increase the sustainability of construction projects. As recyclable construction wastes, concrete and ceramic can replace the natural aggregate in concrete because of their hard and strong physical properties. This research used 25%, 35%, and 45% recycled concrete aggregate (RCA) and ceramic waste as coarse aggregate in producing concrete. Several tests, such as concrete cube compression and splitting tensile tests, were also performed to determine and compare the mechanical properties of the recycled concrete with those of the normal concrete that contains 100% natural aggregate. The concrete containing 35% RCA and 35% ceramic waste showed the best properties compared with the normal concrete.

  10. Control of G1 in the developing Drosophila eye: rca1 regulates Cyclin A.

    Science.gov (United States)

    Dong, X; Zavitz, K H; Thomas, B J; Lin, M; Campbell, S; Zipursky, S L

    1997-01-01

    In the developing eye of Drosophila melanogaster, cells become synchronized in the G1 phase of the cell cycle just prior to the onset of cellular differentiation and morphogenesis. In roughex (rux) mutants, cells enter S phase precociously because of ectopic activation of a Cyclin A/Cdk complex in early G1. This leads to defects in cell fate and pattern formation, and results in abnormalities in the morphology of the adult eye. A screen for dominant suppressors of the rux eye phenotype led to the identification of mutations in cyclin A, string (cdc25), and new cell cycle genes. One of these genes, regulator of cyclin A (rca1), encodes a novel protein required for both mitotic and meiotic cell cycle progression. rca1 mutants arrest in G2 of embryonic cell cycle 16 with a phenotype very similar to cyclin A loss of function mutants. Expression of rca1 transgenes in G1 or in postmitotic neurons promotes Cyclin A protein accumulation and drives cells into S phase in a Cyclin A-dependent fashion.

  11. Optically Guided Photoactivity: Coordinating Tautomerization, Photoisomerization, Inhomogeneity, and Reactive Intermediates within the RcaE Cyanobacteriochrome.

    Science.gov (United States)

    Gottlieb, Sean M; Chang, Che-Wei; Martin, Shelley S; Rockwell, Nathan C; Lagarias, J Clark; Larsen, Delmar S

    2014-05-01

    The RcaE cyanobacteriochrome uses a linear tetrapyrrole chromophore to sense the ratio of green and red light to enable the Fremyella diplosiphon cyanobacterium to control the expression of the photosynthetic infrastructure for efficient utilization of incident light. The femtosecond photodynamics of the embedded phycocyanobilin chromophore within RcaE were characterized with dispersed femtosecond pump-dump-probe spectroscopy, which resolved a complex interplay of excited-state proton transfer, photoisomerization, multilayered inhomogeneity, and reactive intermediates. These reactions were integrated within a central model that incorporated a rapid (200 fs) excited-state Le Châtelier redistribution between parallel evolving populations ascribed to different tautomers. Three photoproducts were resolved and originates from four independent subpopulations, each with different dump-induced behavior: Lumi-Go was depleted, Lumi-Gr was unaffected, and Lumi-Gf was enhanced. This suggests that RcaE may be engineered to act either as an in vivo fluorescent probe (after single-pump excitation) or as an in vivo optogenetic sample (after pump and dump excitation).

  12. O Ora et Labora do mosteiro cisterciense de S. Bento de Cástris no contexto pós-tridentino: do quotidiano monástico às ocasiões festivas

    OpenAIRE

    Conde, Antónia Fialho

    2014-01-01

    A presente abordagem aprecia o mosteiro cisterciense de S. Bento de Cástris enquanto instituição que testemunhou os desígnios tridentinos em Portugal, enfatizando os seus reflexos na liturgia e na prática musical do mosteiro, objecto da investigação em curso pela equipa multidisciplinar do Projecto FCT EXPL/EPH-PAT/2253/2013, Projecto ORFEUS - A Reforma tridentina e a música no silêncio claustral: o mosteiro de S. Bento de Cástris. Esses reflexos, plasmados em diferentes suportes, são tratado...

  13. Cadena de oro para atraer a los herejes. Argumentos de persuasión y estrategias de supervivencia en Fray Juan de Villagarcía, o.p., discípulo de Fray Bartolomé de Carranza

    Directory of Open Access Journals (Sweden)

    Moreno, Doris

    2013-06-01

    Full Text Available This article discusses the biography of the Dominican Friar Juan de Villagarcía, his role in the recatholization of England and his problems with the Inquisition, at the same time that his master, the Toledo archbishop Carranza, was being processed. We will analyze Villagarcía’s manuscript Dialogue or gold chain to attract the heretics, written between 1560 and 1563, and establish similarities and differences with Carranza’s thought.En este artículo se aborda, en primer lugar, el perfil biográfico del dominico fray Juan de Villagarcía, su papel en la recatolización de Inglaterra y sus problemas con el Santo Oficio, paralelos al proceso de su maestro, el arzobispo de Toledo Carranza. Se analizará también su manuscrito: Diálogo o Cadena de oro para atraer a los herejes, escrito entre 1560 y 1563, estableciendo similitudes y distancias respecto al pensamiento de Carranza.

  14. Un capítulo de la historia de las ideas sintácticas en Portugal: en torno a la teoría sintáctica del Ars grammaticae pro lingua lusitana addiscenda (Lyon, 1672 de Bento Pereira (S. I A Chapter in the History of Syntactic Ideas in Portugal: On the Syntactic Theory of Ars grammaticae pro lingua lusitana addiscenda (Lyon 1672 by Bento Pereira (S.I

    Directory of Open Access Journals (Sweden)

    Rogelio Ponce de León Romeo

    2006-06-01

    Full Text Available En este estudio se analizan los presupuestos sintácticos del Ars grammaticae pro lingua lusitana addiscenda (Lyon, 1672 del jesuita portugués Bento Pereira. En primer lugar se reflexiona sobre el papel de la sintaxis en las artes gramaticales impresas durante los siglos XVI y XVII, no sólo portuguesas o castellanas, sino también latinas; a continuación, se pasa a estudiar las características principales de la gramática de Bento Pereira, encuadrándola adecuadamente en el contexto gramaticográfico de su tiempo. Por lo que se refiere a la sintaxis propiamente dicha, se estudia el enfoque del jesuita portugués sobre las relaciones entre los constituyentes, así como la descripción que propone de las cláusulas subordinadas. Finalmente, se analizan someramente las fuentes de las que se sirve Bento Pereira.This paper discusses the syntactic premises of Ars grammaticae pro lingua lusitana addiscenda (Lyon 1672 by Portuguese Jesuit Bento Pereira. First, the role of syntax during the 16th and 17th C. not only in Portuguese and Spanish, but also in Latin printed grammatical arts is discussed. Then, the main characteristics of Bento Pereira´s grammar are accurately presented within the grammatographic context of his time. As regards syntax proper, the Portuguese Jesuist´s approach concerning the relationships between constituents, as well as the description he proposes for subordinate clauses are discussed. Finally, a brief review of Bento Pereira´s sources is presented.

  15. Intoxicações por agrotóxicos entre trabalhadores rurais de fruticultura, Bento Gonçalves, RS Intoxicaciones por agrotóxicos entre trabajadores rurales de fruticultura, Bento Gonçalves, Sur de Brasil Poisoning by pesticides among family fruit farmers, Bento Gonçalves, Southern Brazil

    Directory of Open Access Journals (Sweden)

    Neice Müller Xavier Faria

    2009-04-01

    Full Text Available OBJETIVO: Descrever a exposição ocupacional e a incidência de intoxicações agudas por agrotóxicos, especialmente os organofosforados. MÉTODOS: Estudo descritivo com 290 agricultores da fruticultura do município Bento Gonçalves, RS, conduzido em duas etapas, no ano 2006. Ambas etapas foram completadas por 241 trabalhadores: no período de baixo uso e de intenso uso dos agrotóxicos. Foram coletados dados sobre a propriedade, exposição ocupacional aos agrotóxicos, dados sociodemográficos e freqüência de problemas de saúde utilizando-se questionário padronizado. As intoxicações foram caracterizadas por relato de episódios, sintomas relacionados aos agrotóxicos e exames de colinesterase plasmática. Os casos foram classificados segundo a matriz proposta pela Organização Mundial de Saúde (OMS. RESULTADOS: Em média foram usados 12 tipos de agrotóxicos em cada propriedade, principalmente glifosato e organofosforados. A maioria usava trator durante a aplicação de pesticidas (87%, entregava as embalagens para a coleta seletiva (86% e usava equipamentos de proteção durante as atividades com agrotóxicos (>94%. Dentre os trabalhadores, 4% relataram intoxicações por agrotóxicos nos 12 meses anteriores à pesquisa e 19% em algum momento da vida. Segundo o critério proposto pela OMS, 11% foram classificados como casos prováveis de intoxicação aguda. Entre os que tinham usado organofosforados nos dez dias anteriores ao exame, 2,9% apresentaram dois ou mais sintomas relacionados aos agrotóxicos, assim como redução de 20% da colinesterase. CONCLUSÕES: A ocorrência de intoxicações a partir da percepção dos trabalhadores esteve dentro do esperado, mas a estimativa com base na classificação da OMS captou uma proporção maior de casos. A quebra na safra reduziu o uso de inseticidas e pode explicar a baixa ocorrência de alterações laboratoriais. Os critérios para definição de intoxicação por agrotóxicos, bem

  16. Der Zellzyklusregulator Rca1 - Inhibitor und Substrat des Anaphase-Promoting-Komplexes in Drosophila melanogaster

    OpenAIRE

    Morgenthaler, Christoph

    2014-01-01

    Ein wichtiger Kontrollmechanismus des Zellzyklus ist die irreversible Proteolyse von Zellzyklus-Regulatoren. Dabei markieren E3-Ligasen Zielproteine durch Ubiquitinmoleküle. Für den Abbau in der Mitose und der G1-Phase reguliert der APC/C-Komplex (Anaphase-Promoting-Complex/Cyclosome) als E3-Ligase den zeitlichen Verlauf des Zellzyklus. Die Aktivität des APC/C wiederum wird in den übrigen Zellzyklusstadien durch Phosphorylierung und durch Proteine der Rca1/Emi1-Proteinfamilie inaktiv gehalten...

  17. Results of the IAEA/RCA personal dosemeter intercomparison in the Asian and Pacific region

    International Nuclear Information System (INIS)

    Murakami, H.; Minami, K.; Griffith, R.V.

    1994-01-01

    In 1988, the International Atomic Energy Agency started the Regional Co-operative Agreement project for strengthening the radiation protection infrastructure in the Asian and Pacific region. One component of the initial programme was a regional personal dosimetry intercomparison, which was subsequently conducted in three phases over three years during the period 1990 to 1992. Seventeen organisations of all 14 member states participated in the programmes. Irradiations and data compilation were conducted by the Japan Atomic Energy Research Institute. This paper describes the results of the intercomparison programmes and discusses some features and personal dosimetry problems in the RCA member states. (author)

  18. Bulk magnetic characterization of RCaCrO4 (Rrl02=Y, Pr, Sm ) oxides

    International Nuclear Information System (INIS)

    Martinez, J.L.; Fernandez-Diaz, M.T.; Chen, Q.; Prieto, C.; Andres, A. de; Saez-Puche, R.; Romero, J.

    1995-01-01

    The system RCaCrO 4 (R=Y, Sm, Pr) presents an orthorhombic structure (space group Bmab) at room temperature (RT), similar to that observed in La 2 MO 4 (M=Cu, Ni, Co). The magnetic susceptibility for RCaCrO 4 shows a weak temperature dependence down to 250 K, probably due to the antiferromagnetic ordering of the Cr sublattice above RT. Below RT there is a strong upturn anomaly at 210, 190 and 130 K for Pr, Sm and Y, respectively. This anomaly is associated with the appearance of a weak ferromagnetic component, and could be related to a low temperature structural phase transition, similar to that observed in the related compounds R 2 NiO 4 or La 1.88 Ba 0.12 CuO 4 . In the case of YCaCrO 4 this ferromagnetic component produces a hysteresis curve at 4.5 K with a coercive field of 0.7 T. For PrCaCrO 4 the coercive field is very small ( 4 shows a more complicated behavior with a low temperature magnetic transition (T N2 ∼40 K), which could be associated with either the antiferromagnetic ordering of the Sm sublattice or a spin reorientation in the Cr sublattice. ((orig.))

  19. Marine and coastal environmental education in the context of global climate changes - synthesis and subsidies for ReBentos (Coastal Benthic Habitats Monitoring Network

    Directory of Open Access Journals (Sweden)

    Flávio Augusto S. Berchez

    Full Text Available Abstract As changes in coastal and marine environments are expected to negatively affect Brazilian ecosystems, the importance of Marine Environmental Education (MEE comes to the fore. However, so far only 32 contributions related to this issue have been published in Brazil. The MEE workgroup of ReBentos aims at promoting EE and the communication of marine ecological research to the scholastic public as a whole, as well as to groups which exert an influence on general perception, such as the media, politicians, and scientists. This paper presents an overview of the initiatives of MEE in Brazil, with emphasis on the ReBentos projects and guidelines. The conceptual background of action is based on the Rio'92 Treaty on Environmental Education, thereby implying an MEE with Transdisciplinar, emancipatory and reflexive characteristics, directed to changes in values, principles and attitudes. During the period 2011 to 2015, 10 projects were developed from Alagoas to Santa Catarina States, involving the development, implementation and testing through scientific research of 16 MEE activity-models. The didactic material subsequently produced comprised three books and 21 book-chapters. A public of around 6,500 Conservation Unit visitors, 250 public school teachers and 800 high school students have been impacted to date. To act as monitors and multipliers, 250 undergraduate students and professionals were trained. Research project evaluation generated the publication of nine papers. As a further step, the need for protocol elaboration for each model is placed in evidence, in order to direct and facilitate future initiatives.

  20. Regional Cooperation Agreement for Asia and the Pacific (RCA). A mechanism for nuclear technology transfer

    International Nuclear Information System (INIS)

    Bin Muslim, N.

    1993-01-01

    The paper presents the regional cooperation programs of the IAEA which have as purpose to promote the applications of peaceful uses of atomic energy and to transfer technology to the developing countries. The paper focusses on the (RCA) program for Asia and the Pacific, it is considered the most important mechanism for genuine technology transfer. The annex no 1 lists the full text of the Regional Cooperative Agreement for Research, Development and Training Related to Nuclear Science and Technology, 1987 (13 articles). The annex no.3 lists also the full text of the African Regional Cooperative Agreement for Research, Development and training Related to Nuclear Science and Technology (14 articles). 11 refs., 17 tabs

  1. Characterization of harpy/Rca1/emi1 mutants: patterning in the absence of cell division.

    Science.gov (United States)

    Riley, Bruce B; Sweet, Elly M; Heck, Rebecca; Evans, Adrienne; McFarland, Karen N; Warga, Rachel M; Kane, Donald A

    2010-03-01

    We have characterized mutations in the early arrest gene, harpy (hrp), and show that they introduce premature stops in the coding region of early mitotic inhibitor1 (Rca1/emi1). In harpy mutants, cells stop dividing during early gastrulation. Lineage analysis confirms that there is little change in cell number after approximately cycle-14. Gross patterning occurs relatively normally, and many organ primordia are produced on time but with smaller numbers of cells. Despite the lack of cell division, some organ systems continue to increase in cell number, suggesting recruitment from surrounding areas. Analysis of bromodeoxyuridine incorporation shows that endoreduplication continues in many cells well past the first day of development, but cells cease endoreduplication once they begin to differentiate and express cell-type markers. Despite relatively normal gross patterning, harpy mutants show several defects in morphogenesis, cell migration and differentiation resulting directly or indirectly from the arrest of cell division. Copyright (c) 2010 Wiley-Liss, Inc.

  2. Automatd assessment of the state of central hemodynamics using a radiocardioanalyser RCA 3-01

    International Nuclear Information System (INIS)

    Sivachenko, T.P.; Zozulya, A.A.; Sribnaya, A.F.; Ratmanskij, A.Yu.; Tishchenko, F.M.; Kurenya, A.G.; Krupka, I.N.; Kulagin, S.N.; Protsenko, A.S.

    1987-01-01

    The authors presented the results of a clinical use of a new radiocardioanalyzer RCA 3-01 (manufactured in the USSR) providing for automated measurements and computations of indices of the central hemodynamics during studies using a method of dilution of radioactive nuclides. The main technical potentialities of the device designed on the basis of microprocessor technology, were described. The authors also provided the results of automated computation of the circulating blood volume and the main hemodynamic indices in a group of patients. Values of the hemodynamic indices were shown to correspond to actual ones and comparable to control ones and clinical evidence. The comparison of automated processing with a manual method of calculation indicated a significant coincidence of index values. The clinical use of the radiocardioanalyzer RGA 3-01 for automated assessment of the indices of the cardiovascular system was shown to hold promise among various groups of patients

  3. Role of nuclear energy in Bangladesh: experience with IAEA and RCA

    International Nuclear Information System (INIS)

    Quaiyum, M.A.

    1998-01-01

    Electricity is one of the most convenient forms of energy for sustaining and accelerating industrial growth and thus augmenting the poverty alleviation. All conventional modes of generation of electricity have adverse effects on environment. The nature, quantities and extents of such effects are, however, specific to the type of generations. Taking Bangladesh as a representative developing country the role of nuclear energy is presented. Demand projections for electricity, energy resources and energy development are discussed. It is highlighted that the lack of suitably qualified and experienced manpower has to be addressed properly. Hence training in selected areas is being arranged at home and abroad with own resources and also under different IAEA, RCA and bilateral assistance programmes. The paper also discusses the safety and environmental aspects of nuclear energy and highlights the contribution of IAEA and RCA in establishing global safety culture and pollution free environment. It is concluded that Bangladesh has to depend heavily on imported fuel. Among the important fuels, nuclear is a viable proposition and hence needs careful consideration. This is of course true for all other developing countries like Bangladesh. It is hoped that in order to dispel the apprehension of nuclear proliferation, the concept of regional reprocessing centre may be thought of. This centre may be planned and implemented by pulling resources and expertise of developing countries, specially the neighbouring ones, so as to recover the fissile materials from the spent fuel and use them in the fast breeder reactor which may be considered as the energy source of the future, and thus sustainable development can be ensured. (author)

  4. IAEA-RCA Co-ordinated Research Program on Reference Asian Man

    International Nuclear Information System (INIS)

    Koyanagi, Taku

    1990-01-01

    The Research Coordination Meeting was held in Mito City, Japan on October 17-21, 1988, inviting the chief investigating scientists from 11 RCA member countries to discuss practical plans for the Coordinated Research Program (CRP) on 'Compilation of Anatomical, Physiological and Metabolic Characteristics for a Reference Asian Man' based on the decision taken at the Project Formulation Meeting for the RCA Project 'Strengthening Radiation Protection' Tokyo, November 1987. Significance of the setting 'Reference Man' for Asian peoples to estimate more realistic radiation doses by applying the real typical physical, physiological and metabolic parameters for them instead of those recommended by ICRP based on the data for 'Caucasian Man' has been indicated by whole member countries and recognized again at the Meeting. The present status of 'Reference Man-oriented Studies' in each countries was presented by the participants and certain difference or difficulties were pointed out among the countries depending on the geographical, social, or economical conditions as well as the ethnic circumstances. After the mutual discussions and exchange of up-to-date information, the general conclusions were drawn as follows: acknowledging the importance of the CRP, research works should be carried out in each country with the expected supports from IAEA and other member countries. The first priority is given on the measurements of human physique (and internal organs) followed by the food consumption survey. Trace element analysis would be done by the countries where possible. The standard manual for data collection might be necessary. The establishments of Co-ordination Center or central body with data base and also subgroup systems are desirable to promote the CRP. (author)

  5. Contributions of Pakistan in the IAEA/RCA/UNDP regional project on management of marine coastal environment and its pollution

    International Nuclear Information System (INIS)

    Qureshi, R.M.; Mashiatullah, A.; Fazil, M.; Ahmad, E.; Tasneem, M.A.; Khan, H.A.; Sajjad, M.I.

    2002-01-01

    The International Atomic Energy Agency (IAEA), Vienna, launched a five years (duration: 1998 - 2002) Joint Project on 'Better Management of the Environment and Industrial Growth Through Isotope and Radiation Technology (RAS/97/030)' in co-operation with the RCA (Regional Co-operative Agreement) office, Vienna, and United Nations Development Programme (UNDP). The Marine Sub-project entitled 'Management of Marine Coastal Environment and its Pollution (RAS/8/083)' is 'Output 1.2' of this joint project. Pakistan is very actively participating in activities of the IAEA/RCA/UNDP Marine Sub-Project that were planned in two Project Formulation Meetings (PFMs) held at Manila, Philippines, during 1998. In Pakistan, various activities of the national marine pollution project are being administered by the nuclear institute namely, Pakistan Institute of Nuclear Science and Technology (PINSTECH), in collaboration with national end user institutions. To-date, Pakistan has significantly contributed in this project, both at national level and at RCA regional level. This paper highlights the progress and some accomplishments of Pakistan, up to the year 2001, for marine pollution studies related to the IAEA/RCA regional marine sub project. (author)

  6. Sustentabilidade, Planejamento Urbano e Instrumentos de Gestão do Patrimônio e da Paisagem Cultural em Bento Gonçalves/RS

    Directory of Open Access Journals (Sweden)

    Cristiane Bertoco

    2015-08-01

    Full Text Available Buscando instrumentos mais sustentáveis de preservação do patrimônio cultural, o trabalho se propõe a pesquisar como se dá a relação entre os instrumentos de gestão preservacionistas e aqueles voltados ao planejamento urbano municipal, utilizando como metodologias revisão bibliográfica e estudo de caso. Busca uma discussão teórica sobre patrimônio cultural e desenvolvimento sustentável, valorização e reabilitação através do turismo e indicações geográficas, gestão e planejamento urbano através do Plano Diretor. Como estudo de caso, adota-se o município de Bento Gonçalves, no Rio Grande do Sul, polo turístico e vitivinícola, abordado sob dois pontos de vista: a valorização do patrimônio através de roteiros turísticos e indicações geográficas, e a gestão e planejamento urbano na preservação dos bens edificados e da paisagem urbana e rural. O estudo resulta na reflexão dos desafios na construção de um pacto de gestão da paisagem cultural através do Plano Diretor e dos Conselhos Municipais.   Seeking more sustainable instruments of cultural heritage preservation, the study aims to investigate how is the relationship between preservationists management tools and those focused on municipal urban planning, using methodologies such as literature review and case study. Search a theoretical discussion of cultural heritage and sustainable development, recovery and rehabilitation through tourism and geographical indications, management and urban planning through the Master Plan. As a case study, we adopt the municipality of Bento Gonçalves, in Rio Grande do Sul, tourist pole and wine, approached from two points of view: the recovery of itinerary tours and geographical indications, and the management and urban planning in preserving of real estate and strengthen the urban and rural landscape. The study results in the reflection of the challenges in building a pact management of the cultural landscape through the

  7. Florística e estrutura fitossociológica em floresta ombrófila densa submontana na barragem do rio São Bento, Siderópolis, Estado de Santa Catarina = Floristic composition and phytosociological structure in a submontane ombrophilous dense forest at São Bento river dam, Siderópolis, Santa Catarina State

    OpenAIRE

    Sinara Colonetti; Vanilde Citadini-Zanette; Rafael Martins; Robson dos Santos; Edilane Rocha; João André Jarenkow

    2009-01-01

    Apresentam-se os resultados de levantamentos florístico e fitossociológico em remanescente de Floresta Ombrófila Densa Submontana circunjacente à barragem do rio São Bento, objetivando fornecer dados primários para ações de restauração e conservação destaformação. A área está localizada no Sul de Santa Catarina, município de Siderópolis. Utilizou-se como área amostral um hectare e foram registrados indivíduos com DAP ≥ 5 cm e quantificados seus descritores estruturais. Foram identificadas 107...

  8. The Neurospora rca-1 gene complements an Aspergillus flbD sporulation mutant but has no identifiable role in Neurospora sporulation.

    OpenAIRE

    Shen, W C; Wieser, J; Adams, T H; Ebbole, D J

    1998-01-01

    The Aspergillus nidulans flbD gene encodes a protein with a Myb-like DNA-binding domain that is proposed to act in concert with other developmental regulators to control initiation of conidiophore development. We have identified a Neurospora crassa gene called rca-1 (regulator of conidiation in Aspergillus) based on its sequence similarity to flbD. We found that N. crassa rca-1 can complement the conidiation defect of an A. nidulans flbD mutant and that induced expression of rca-1 caused coni...

  9. Persistência de plantas medicinais em sistemas agroflorestais no município de São Bento do Sul, SC, Brasil

    Directory of Open Access Journals (Sweden)

    A.L. Hanisch

    2013-01-01

    Full Text Available No final da década de 90, a comunidade de Rio Natal, no município de São Bento do Sul, SC, passou a fazer parte de uma Área de Preservação Ambiental e desde então, muitas áreas de cultivo, paulatinamente, estão retomando o processo de formação florestal. Neste cenário, foi sugerido pela comunidade, a possibilidade de cultivo de plantas medicinais adaptadas às condições de sombreamento. Em atendimento a essa demanda foi realizada uma pesquisa participativa na comunidade, de 2005 a 2008, onde foram avaliadas 14 espécies de plantas medicinais com potencial de mercado, cultivadas em áreas sombreadas, em três propriedades familiares. Foram avaliados: taxa de sobrevivência das espécies, incidência de doenças e pragas, teor de massa seca e altura das plantas. Apresentaram persistência ao cultivo em áreas sombreadas as espécies: Curcuma longa L. (açafrão-da-índia; Arctium lappa L. (bardana; Pfaffia glomerata (Spreng Pedersen (fáfia ou ginseng-brasileiro; Mikania glomerata Sprengel (guaco; Alternanthera brasiliana L. Kuntze (penicilina; Pogostemon cablin (Blanco Benth (patchuli e Maytenus ilicifolia Mart. Ex Reissek (espinheira-santa.

  10. Analysis of influence of the inclusion of residue of kaolin on the properties and on the variation of major oxides present in clay city Bento Fernandes (RN)

    International Nuclear Information System (INIS)

    Silva, Hugo Fernandes Medeiros de; Lima, Cassiano dos Santos; Silva, Gilson Garcia da; Machado, Tercio Graciano; Albuquerque, Rosanne Azevedo de; Gomes, Uilame Umbelino

    2011-01-01

    Research Foundation for Support of Education and Technological Development of Rio Grande do Norte - FUNCERN found that 38% of deposits visited in RN products sold in other states, 20% did not sell tiles RN, 8% preferred the tiles outside. All to supply a market segment demanding and are looking for differentiated products, which require manufacturers of certified quality products contributing to the quality process in the construction industry. It is known that the ceramic bodies are manufactured from the composition of two or more materials with different characteristics in their composition. Thus, one of the key steps is the dosage of raw materials and additives. This device allows to target the many wastes from industry. This paper aims to study the physical and mechanical properties of ceramic body resulting from the inclusion of residual kaolin clay on the city of Bento Fernandes (RN), analyzing the influence of variation of major oxides present in the raw material on the behavior of the final product. (author)

  11. Rapid Identification of Seven Waterborne Exophiala Species by RCA DNA Padlock Probes.

    Science.gov (United States)

    Najafzadeh, M J; Vicente, V A; Feng, Peiying; Naseri, A; Sun, Jiufeng; Rezaei-Matehkolaei, A; de Hoog, G S

    2018-03-05

    The black yeast genus Exophiala includes numerous potential opportunistic species that potentially cause systematic and disseminated infections in immunocompetent individuals. Species causing systemic disease have ability to grow at 37-40 °C, while others consistently lack thermotolerance and are involved in diseases of cold-blooded, waterborne vertebrates and occasionally invertebrates. We explain a fast and sensitive assay for recognition and identification of waterborne Exophiala species without sequencing. The ITS rDNA region of seven Exophiala species (E. equina, E. salmonis, E. opportunistica, E. pisciphila, E. aquamarina, E. angulospora and E. castellanii) along with the close relative Veronaea botryosa was sequenced and aligned for the design of specific padlock probes for the detection of characteristic single-nucleotide polymorphisms. The assay demonstrated to successfully amplify DNA of target fungi, allowing detection at the species level. Amplification products were visualized on 1% agarose gels to confirm specificity of probe-template binding. Amounts of reagents were reduced to prevent the generation of false positive results. The simplicity, tenderness, robustness and low expenses provide padlock probe assay (RCA) a definite place as a very practical method among isothermal approaches for DNA diagnostics.

  12. Impacts of using spectral nudging on regional climate model RCA4 simulations of the Arctic

    Directory of Open Access Journals (Sweden)

    P. Berg

    2013-06-01

    Full Text Available The performance of the Rossby Centre regional climate model RCA4 is investigated for the Arctic CORDEX (COordinated Regional climate Downscaling EXperiment region, with an emphasis on its suitability to be coupled to a regional ocean and sea ice model. Large biases in mean sea level pressure (MSLP are identified, with pronounced too-high pressure centred over the North Pole in summer of over 5 hPa, and too-low pressure in winter of a similar magnitude. These lead to biases in the surface winds, which will potentially lead to strong sea ice biases in a future coupled system. The large-scale circulation is believed to be the major reason for the biases, and an implementation of spectral nudging is applied to remedy the problems by constraining the large-scale components of the driving fields within the interior domain. It is found that the spectral nudging generally corrects for the MSLP and wind biases, while not significantly affecting other variables, such as surface radiative components, two-metre temperature and precipitation.

  13. Three genes for mitochondrial proteins suppress null-mutations in both Afg3 and Rca1 when over-expressed.

    Science.gov (United States)

    Rep, M; Nooy, J; Guélin, E; Grivell, L A

    1996-08-01

    The AFG3 gene of Saccharomyces cerevisiae encodes a mitochondrial inner membrane protein with ATP-dependent protease activity. To gain more insight into the function of this protein, multi-copy suppressors of an afg3-null mutation were isolated. Three genes were found that restored partial growth on non-fermentable carbon sources, all of which affect the biogenesis of respiratory competent mitochondria: PIM1(LON) encodes a matrix-localized ATP-dependent protease involved in the turnover of matrix proteins; OXA1(PET1402) encodes a putative mitochondrial inner membrane protein involved in the biogenesis of the respiratory chain; and MBA1 encodes a mitochondrial protein required for optimal respiratory growth. All three genes also suppressed a null mutation in a related gene, RCA1, as well as in the combination of afg3- and rca1-null.

  14. Recombination reduction at the c-Si/RCA oxide interface through Ar-H2 plasma treatment

    Science.gov (United States)

    Landheer, Kees; Bronsveld, Paula C. P.; Poulios, Ioannis; Tichelaar, Frans D.; Kaiser, Monja; Schropp, Ruud E. I.; Rath, Jatin K.

    2017-02-01

    An Ar-H2 plasma treatment was applied on an ultrathin RCA oxide to create well-passivated silicon wafers with symmetric c-Si/SiOx:H/a-Si:H passivation layer stacks. The effective lifetime of these samples increased from 10 μs to 4 ms after annealing at 200 °C through Ar-H2 plasma treatment of the oxide. The results indicate that the plasma treatment can modify the RCA oxide and this enables atomic hydrogen diffusion at low annealing temperature, leading to a well passivated c-Si/SiOx:H interface. This might provide new possibilities to use wet chemical oxides in c-Si solar cells, for example as tunnel contacts.

  15. The contribution of the UNDP/RCA/IAEA programmes to the development of nuclear technology in the Asia Pacific Region

    International Nuclear Information System (INIS)

    Easey, J.F.

    1994-01-01

    The UNDP/RCA/IAEA Programmes are involving Member States in the Asia Pacific Region in projects to develop and increase the use of nuclear technologies. These efforts have already increased the level of awareness amongst the Region's scientists, engineers, technologists, and decision makers and has provided significant training to the scientists and engineers to enable them to play a role in technical back stopping at a national level. A new project has been started in 1993 and this will seek to expand the contribution of the nuclear technologies into further industrial and environmental fields. Much of the success of the programmes is credited to the high level of Regional Co-operative Agreement (RCA) for research, development and training related to nuclear science and technology in Asia and the Pacific

  16. Current status of food irradiation in overseas (2013). From the meeting report of RCA food irradiation project

    International Nuclear Information System (INIS)

    Todoriki, Setsuko

    2013-01-01

    The report introduces the activity of RCA (Regional Cooperative Agreement for Research Development and Training Related to Nuclear Science and Technology for Asia and Pacific) food irradiation project (RAS/5/057) and information obtained at the two workshops on current status of Asia and Pacific areas together with EU, USA and Japan. Also current trends of RAS/5/057 Implementing Best Practices for food irradiation for plant sanitary and phytosanitary purposes are described. Amount of food irradiation products of RCA member countries, minimum adopted doses for quarantine harmful insects (70 to 232 Gy) and import amount of fruits of USA (79 to 5500 tons) are tabulated. Finally current status of Japan is explained. (S. Ohno)

  17. Recombination reduction at the c-Si/RCA oxide interface through Ar-H2 plasma treatment

    NARCIS (Netherlands)

    Landheer, K.; Bronsveld, P.C.P.; Poulios, I.; Tichelaar, F.D.; Kaiser, M.; Schropp, R.E.I.; Rath, J.K.

    2017-01-01

    An Ar‑H2 plasma treatment was applied on an ultrathin RCA oxide to create well-passivated silicon wafers with symmetric c‑Si/SiOx:H/a‑Si:H passivation layer stacks. The effective lifetime of these samples increased from 10 μs to 4 ms after annealing at 200 °C through Ar‑H2 plasma treatment of the

  18. Analyzing the international competitiveness of the industry in Portugal, Ireland, Greece and Spain using revealed comparative advantages (RCA) indicators

    OpenAIRE

    Oelgemöller, Jens

    2012-01-01

    This paper sheds light on the export structure of the four European countries Portugal, Ireland, Greece and Spain, the so called PIGS countries. These countries were all hit by the economic downturn in the course of the financial crisis and have been struggling with the national debt crisis and recession. One way to identify sectoral international competitiveness is provided by the revealed comparative advantage index developed by Balassa (RCA 1). This indicator evolved through several studie...

  19. Geological map of Uruguay Esc 1,100,000. Cololo Sheet 0-19

    International Nuclear Information System (INIS)

    Morales, H.; Ford, I.; Montana, J.

    1990-01-01

    This work is about the geological map of Uruguay Esc.1.100.000 (Cololo) and the explanatory memoranda which describes the geological , lithological and sedimentological characteristics soils of Holocene, Oligocene and upper Cretaceous in Asencio and Fray Bentos formations

  20. Os excessos da identidade: Bento XVI e a questão da tolerância Excesses of identity: Benedict XVI and the issue of tolerance

    Directory of Open Access Journals (Sweden)

    Homero Santiago

    2008-01-01

    Full Text Available Partindo de algumas das polêmicas opiniões de Bento XVI, o artigo busca compreender a base doutrinária delas e discutir os seus efeitos para a questão da tolerância religiosa. Depois de uma apresentação do que entende por tolerância, propõe um percurso através da encíclica Deus caritas est, que embasa a nova doutrina papal numa interpretação particular da noção de "amor de Deus". Por fim, tenta-se mostrar como esse "amor", mediante uma ênfase exagerada da idéia de identidade, torna-se nos documentos papais um instrumento de combate a todas as diferenças, pondo a perder a possibilidade de convivência entre as religiões e, por conseqüência, semeando o fundamentalismo.This article tries to comprehend the doctrinal base of some polemical assessments of Benedict XVI; discussing its effects on the issue of religious tolerance. After presenting what is understood to mean tolerance, it proposes a way through the encyclical letter Deus caritas est; in this letter, the new papal doctrine is founded on a particular interpretation of the notion of "God's love". Lastly, it intends to show how this "love", by an exaggerated emphasis on the idea of identity, becomes an instrument of fight against every difference, spoiling the possibility of a pacific relationship among the religions and, consequently, sowing the seeds of fundamentalism.

  1. Flutuação populacional de Grapholita molesta (Busck com armadilhas de feromônio sexual na cultura do pessegueiro em Bento Gonçalves, RS, Brasil Seasonal fluctuation of Grapholita molesta (Busck using sexual pheromon in peach orchards in Bento Gonçalves, RS, Brazil

    Directory of Open Access Journals (Sweden)

    Cristiano João Arioli

    2005-02-01

    Full Text Available A flutuação populacional de machos de Grapholita molesta (Busck, 1916 (Lepidoptera: Tortricidae foi avaliada em dois pomares comerciais de pessegueiro da cultivar Chiripá em Bento Gonçalves, RS, entre julho de 2000 a junho de 2002. Os insetos foram capturados por meio de armadilhas Delta (duas por pomar iscadas com a formulação comercial do feromônio sexual sintético (E-8-dodecenil-acetato + Z-8-dodecenil-acetato + Z-8-dodecenol e avaliados semanalmente. Foram observados quatro picos populacionais durante o período de produção do pessegueiro: quarta semana de agosto, primeira de novembro e dezembro, e segunda de janeiro. A temperatura média dos sete dias anteriores à cada avaliação foi correlacionada positivamente com o número de adultos da G. molesta capturados nas armadilhas. As informações deste trabalho podem ser utilizadas para orientar os produtores de pessegueiro, visando a direcionar as táticas de controle para os períodos em que a população do inseto for mais elevada nos pomares comerciais.Seasonal fluctuation of male Grapholita molesta (Busck, 1916 (Lepidoptera: Tortricidae was evaluated in two commercial peach orchards cv Chiripá in Bento Gonçalves, RS, from June of 2000 to July of 2002. The insects were evaluated weekly using Delta traps (two/orchard baited with commercial synthetic sex pheromone (E-8-dodecenil-acetato + Z-8-dodecenil-acetato + Z-8-dodecenol. Four peaks were observed during peach production period: last week of August, first of November and December and second of January. Medium temperature seven days before evaluation was positively correlated with catches of male G. molesta in the traps. Information about seasonal fluctuation can be used for growers as a tool to guide insecticide treatments for pest control in peach orchards.

  2. Florística e estrutura fitossociológica em floresta ombrófila densa submontana na barragem do rio São Bento, Siderópolis, Estado de Santa Catarina = Floristic composition and phytosociological structure in a submontane ombrophilous dense forest at São Bento river dam, Siderópolis, Santa Catarina State

    Directory of Open Access Journals (Sweden)

    Sinara Colonetti

    2009-10-01

    Full Text Available Apresentam-se os resultados de levantamentos florístico e fitossociológico em remanescente de Floresta Ombrófila Densa Submontana circunjacente à barragem do rio São Bento, objetivando fornecer dados primários para ações de restauração e conservação destaformação. A área está localizada no Sul de Santa Catarina, município de Siderópolis. Utilizou-se como área amostral um hectare e foram registrados indivíduos com DAP ≥ 5 cm e quantificados seus descritores estruturais. Foram identificadas 107 espécies, pertencentes a 42 famílias botânicas, totalizando 1.715 indivíduos. As espécies com maiores valores de importância (VI foram Euterpeedulis Mart., Casearia sylvestris Sw. e Bathysa australis (St.-Hil. K. Schum. Entre as espécies identificadas, encontrou-se elevado índice de zoofilia e zoocoria. Pela característica florística eabundância de serapilheira, a área encontra-se em estádio avançado de regeneração natural.Aiming to provide primary data to be used in restoration programs, data from a floristic and phytosociological survey at a Submontane Ombrophilous Dense Forest remnant around São Bento river dam (Siderópolis municipality, Santa Catarina State, southern Brazil are presented. All tree individuals with a diameter at breast height (DBH≥ 5 cm were recorded (1 ha plot. 1,715 individuals belonging to 107 species and 42 botanical families were identified. Euterpe edulis Mart., Casearia sylvestris Sw. and Bathysa australis (St.-Hil. K.Schum. were the species with higher values of structural importance.High index of zoophily and zoochory were registered among the identified species. From the floristic composition and litter abundance, it can be assumed that the studied area corresponds to an advanced stage of natural regeneration.

  3. Terminología botánica indígena en el vocabulario castellanomexicano (1555 de Fray A. De Molina

    Directory of Open Access Journals (Sweden)

    Manuel Galeote

    2002-01-01

    Full Text Available Las voces indígenas de la flora americana, que fray Alonso de Molina incluye en la sección castellana de su obra: Aqui comiença vn vocabulario en la lengua castellana y mexicana (México, Juan Pablos, 1555 se analizan desde el punto de vista histórico y sociolingüístico. Se trata del primer vocabulario de Molina —el Nebrija de las Indias — y, además, el primer diccionario impreso en México y en América. En las entradas castellanas, los términos indígenas americanos de la flora (plantas y frutas constituyen uno de los campos onomasiológicos más numerosos (maíz, cacao, maguey, chía, ají, etc. De los once términos indígenas hemos contabilizado casi un centenar de ocurrencias. En conclusión, este vocabulario muestra el fondo léxico patrimonial del español y los indoamericanismos que se acomodaron a las estructuras de la lengua castellana.

  4. Terminología botánica indígena en el vocabulario castellano-mexicano (1555 de Fray A. de Molina

    Directory of Open Access Journals (Sweden)

    Galeote Manuel

    2002-06-01

    Full Text Available

    Las voces indígenas de la flora americana, que fray Alonso de Molina incluye en la sección castellana de su obra: Aquí comience un vocabulario en la lengua castellana y mexicana (México, Juan Pablos, 1555 se analizan desde el punto de vista histórico y sociolingüístico. Se trata del primer vocabulario de Molina el Nebrija de las Indias y, además, el primer diccionario impreso en México y en América. En las entradas castellanas, los términos indígenas americanos de la flora (plantas y frutas constituyen uno de los campos onomasiológicos más numerosos (maíz, cacao, maguey, chía, ají, etc. De los once términos indígenas hemos contabilizado casi un centenar de ocurrencias. En conclusión, este vocabulario muestra el fondo léxico patrimonial del español y los indoamericanismos que se acomodaron a las estructuras de la lengua castellana.

  5. Identification and functional characterization of Rca1, a transcription factor involved in both antifungal susceptibility and host response in Candida albicans.

    Science.gov (United States)

    Vandeputte, Patrick; Pradervand, Sylvain; Ischer, Françoise; Coste, Alix T; Ferrari, Sélène; Harshman, Keith; Sanglard, Dominique

    2012-07-01

    The identification of novel transcription factors associated with antifungal response may allow the discovery of fungus-specific targets for new therapeutic strategies. A collection of 241 Candida albicans transcriptional regulator mutants was screened for altered susceptibility to fluconazole, caspofungin, amphotericin B, and 5-fluorocytosine. Thirteen of these mutants not yet identified in terms of their role in antifungal response were further investigated, and the function of one of them, a mutant of orf19.6102 (RCA1), was characterized by transcriptome analysis. Strand-specific RNA sequencing and phenotypic tests assigned Rca1 as the regulator of hyphal formation through the cyclic AMP/protein kinase A (cAMP/PKA) signaling pathway and the transcription factor Efg1, but also probably through its interaction with a transcriptional repressor, most likely Tup1. The mechanisms responsible for the high level of resistance to caspofungin and fluconazole observed resulting from RCA1 deletion were investigated. From our observations, we propose that caspofungin resistance was the consequence of the deregulation of cell wall gene expression and that fluconazole resistance was linked to the modulation of the cAMP/PKA signaling pathway activity. In conclusion, our large-scale screening of a C. albicans transcription factor mutant collection allowed the identification of new effectors of the response to antifungals. The functional characterization of Rca1 assigned this transcription factor and its downstream targets as promising candidates for the development of new therapeutic strategies, as Rca1 influences host sensing, hyphal development, and antifungal response.

  6. A Report on IAEA/RCA C7-RAS 6/061-004 Training Course in Chiba, Japan in 2014

    International Nuclear Information System (INIS)

    Kosuda, Shigeru; Saga, Tsuneo; Paez, Diana

    2015-01-01

    The C7-RAS 6/061-004 training course by the International Atomic Energy Agency/Regional Cooperative Agreement (IAEA/RCA) was held in Chiba in 2014. The syllabus, pre- and post-course evaluations, and survey questionnaire results were assembled in this course. The post-course evaluation, including 32 questions similar to the pre-course evaluation, was performed right after the end of the final educational lecture. The mean score showed an improvement, with the score rising from 57.0 points at the beginning to 66.5 points at the end. Among 22 trainees, the greatest score was in a higher range, with an improvement from 82 points at the beginning to 88 points at the end. The grading distribution, with regard to the training course, was as follows: excellent (68.2%), good (31.8%), average (0%), fair (0%), and poor (0%). This report on the training course, held in Chiba in 2014, will contribute to the future global plans of IAEA/RCA. Continuous training courses in member states are required to decrease the present disparities in the knowledge level, instrumentation, and human resources

  7. An overview of the RCA/IAEA activities in the Australasian region using nuclear analysis techniques for monitoring air pollution

    International Nuclear Information System (INIS)

    Markwitz, Andreas

    2005-01-01

    The International Atomic Energy Agency (IAEA) via the Regional Co-operative Agreement (RCA) has identified air particulate matter pollution as a major transboundary environmental issue in the Australasian region. Sixteen countries in the region spanning from Pakistan to the Philippines and from China to New Zealand are participating in the regional programme RAS/7/013-Improved information of urban air quality management in the RCA region' that started in 1997. New Zealand is the lead-country for this programme in which nuclear analytical techniques, such as particle induced X-ray emission (PIXE), neutron activation analysis (NAA) and X-ray fluorescence spectrometry (XRF) are used to measure key elements in PM 2.5-0 and PM 10-2.5 filters from GENT stacked samplers collected twice weekly. Major sources of air particulate matter pollution are identified using statistical source apportionment techniques. To identify transboundary air particulate matter pollution events, the data is collated in a large database. Additionally, the data is used by end-users of the participating countries in the programme. An overview is presented. (author)

  8. Una Normal y un Método. La iniciativa de Fray Matías de Córdova en Chiapas (1828

    Directory of Open Access Journals (Sweden)

    Morelos Torres Aguilar

    2016-01-01

    Full Text Available El art culo es producto de una investigaci n m s amplia sobre las iniciativas de ense anza que fueron realizadas en el Estado de Chiapas, en M xico, durante el siglo XIX, y se centra en la idea que dio origen a la Escuela Normal de Ense anza Primaria, fundada en Ciudad Real por fray Mat as de C rdova en 1828. El principal objetivo de la investigaci n consiste en conocer, describir, analizar y comprender las principales caracter sticas de esta instituci n, as como el m todo de lectoescritura inventado por su fundador, el cual fue aplicado con xito en la misma. Un segundo prop sito consiste en contextualizar dicha escuela normal respecto a otras que surgieron en M xico durante el mismo per odo, como la de Oaxaca o Zacatecas. Por ltimo, se pretende relacionar esta iniciativa con las tendencias educativas de la poca, en particular con la Escuela Lancasteriana, y asimismo analizar su trascendencia. El m todo utilizado consisti en una UHYLVLyQ GRFXPHQWDO ELEOLRJUi FD \\ KHPHURJUi FD VREUH HO WHPD FRQ HO PDUFR te rico de la historia institucional, la nueva historia de las ideas pedag gicas -a partir del planteamiento de Antonio Novoa-, y un modelo hermen utico que permiti profundizar en las caracter sticas de la primera Normal de Chiapas. A partir de la investigaci n se puede concluir que aunque la Normal solo funcion durante un corto tiempo, el m todo de ense anza de Mat as de C rdova que le dio fundamento tuvo una amplia trascendencia, pues se sigui empleando a lo largo del siglo XIX e incluso a principios del XX, tanto en el Estado de Chiapas como en otros lugares de M xico. De esta manera, la investigaci n aporta conocimientos relevantes sobre la historia de la educaci n en el Estado de Chiapas en la primera mitad del siglo XIX.

  9. La disfuncionalidad familiar y su incidencia en el rendimiento académico de los estudiantes del Colegio Universitario "Fray Vicente Solano", año lectivo 2008-2009

    OpenAIRE

    Merchán Alvarez, María de Lourdes

    2010-01-01

    La presente investigación aborda el tema: La Disfuncionalidad Familiar y su incidencia en el Rendimiento Académico de los estudiantes del Colegio Universitario Fray Vicente Solano, en el año lectivo 2008-2009. Esta investigación está dividida en dos partes, la primera parte es de carácter teórico sustentada en un enfoque Sistémico Estructural, la segunda es fundamentalmente práctico, para lo cual se empleó técnicas investigativas de tipo: cuantitativo (Test de la familia, datos sobre rend...

  10. Special report for UNDP on regional RCA project for Asia and the Pacific on industrial applications of isotopes and radiation technology. Technical, economic and commercial analyses

    International Nuclear Information System (INIS)

    1980-01-01

    The report contains seven sub-projects for RCA countries on the following problems: tracer technology in industry; non-destructive testing practice; radiation processing; nucleonic control systems for paper manufacture and steel manufacture; mineral exploration, mining and process control; nuclear instruments maintenance practices

  11. Detection of denitrification genes by in situ rolling circle amplification - fluorescence in situ hybridization (in situ RCA-FISH) to link metabolic potential with identity inside bacterial cells

    DEFF Research Database (Denmark)

    Hoshino, Tatsuhiko; Schramm, Andreas

    2010-01-01

    target site. Finally, the RCA product inside the cells was detected by standard fluorescence in situ hybridization (FISH). The optimized protocol showed high specificity and signal-to-noise ratio but low detection frequency (up to 15% for single-copy genes and up to 43% for the multi-copy 16S rRNA gene...... as Candidatus Accumulibacter phosphatis by combining in situ RCA-FISH with 16S rRNA-targeted FISH. While not suitable for quantification because of its low detection frequency, in situ RCA-FISH will allow to link metabolic potential with 16S rRNA (gene)-based identification of single microbial cells.......). Nevertheless, multiple genes (nirS and nosZ; nirS and the 16S rRNA gene) could be detected simultaneously in P. stutzeri. Environmental application of in situ RCA-FISH was demonstrated on activated sludge by the differential detection of two types of nirS-defined denitrifiers; one of them was identified...

  12. Roteiro Caminhos de Pedra – Bento Gonçalves – Rio Grande do Sul: uma reflexão sobre o número de visitantes no período de 1997 a 2011

    Directory of Open Access Journals (Sweden)

    Rita L. Michelin

    2014-01-01

    Full Text Available Rural tourism is a segment of tourism that uses the spaceof rurality main attraction, through the manifestations of the habits and customs of a particular culture. The object of study was the Caminhos de Pedra Attractive, located in Bento Gonçalves city, at Rio Grande do Sul state. In This local, the visitors can learn about the history of the Italian descendants immigrants and have direct contact with the locals. The research method was through desk research oft hehistoryofvisitations in the local. The results showed that the number of visitors has grown considerably since its was introduce, as well as the number of enterprise, demonstrating a good example of rural tourism done contributing this way to its consolidation.

  13. Restrições e estratégias na determinação do preço no mercado moveleiro de São Bento do Sul (SC)

    OpenAIRE

    Della Justina, Másimo

    2004-01-01

    Tese (doutorado) - Universidade Federal de Santa Catarina, Centro Tecnológico. Programa de Pós-Graduação em Engenharia de Produção. Esta é uma pesquisa qualitativa aplicada que analisa as restrições impostas à liberdade de determinação do preço no mercado moveleiro de São Bento do Sul (SC). A hipótese 1 supõe que há restrições que não aparecem na função típica de custos de produção e que podem limitar a liberdade de determinação do preço em uma empresa de produção industrial de móveis oper...

  14. The IAEA regional cooperative agreement programme (RCA) on enhancement and harmonization of radiation protection in the Asia-Pacific Region (1998-2002)

    International Nuclear Information System (INIS)

    Cameron, R.F.; Oresegun, M.O.

    2000-01-01

    The IAEA Regional Cooperative Agreement (RCA) was initiated in 1972, and currently consists of 17 Member States from East Asia and Oceania. These countries are Australia, Bangladesh, China, India, Indonesia, Japan, Korea, Malaysia, Myanmar, Mongolia, New Zealand, Pakistan, Philippines, Singapore, Sri Lanka, Thailand and Vietnam. The RCA is one of three cooperative agreements under the aegis of the IAEA, the other two being for Africa (AFRA) and Latin America (ARCAL). The RCA agreement has been extended five times, as it meets particular needs of the participating countries. The region covered by the RCA comprises nearly half of the world's population and is undergoing a rapid expansion in nuclear power development and in the uses of radiation sources (radioactive materials and irradiating equipment). A number of activities in a wide range of areas of Agency interest are carried out under RCA. The Project to Strengthen Radiation Protection Infrastructures was initiated in 1988, as a five year programme, to offer a regional response to some of the radiation protection issues that were raised following the Chernobyl accident. It was extended into Phase 2 from 1993 to 1998 and has now reached a new phase. The IAEA has a dual role to establish standards in radiation protection and safety and to provide for their application. Since the status of the implementation of radiation safety laws and regulations is variable within the RCA countries, the primary focus has been on providing assistance to member states in the drafting of laws and regulations to ensure that sources are authorized and are properly controlled. A number of accidents worldwide have resulted from inappropriate or a complete lack of regulations on the control of sources. However as countries develop, their needs change and it is important that the RCA project in radiation protection changes with them. Hence the new Phase 3 programme in radiation protection has a mixture of events to strengthen radiation

  15. Inovações tecnológicas na indústria de móveis: uma avaliação a partir da concentração produtiva de Bento Gonçalves (RS

    Directory of Open Access Journals (Sweden)

    Cláudia Maria Sonaglio

    2010-07-01

    Full Text Available O artigo avalia a adoção de inovações tecnológicas na indústria de móveis retilíneos residenciais de Bento Gonçalves, a principal aglomeração produtiva do Rio Grande do Sul e uma das mais importantes do Brasil. Faz-se uma análise descritiva dos dados obtidos por meio de questionários enviados às empresas, e conclui-se que as inovações mais importantes para a indústria são: de produto, a inclusão de produtos novos para a empresa, mas já existentes no mercado, e alterações no desenho/estilo dos móveis; de processo, mudanças tecnológicas parciais em processos já adotados e a adoção de processos já existentes no setor; e organizacionais, a implementação de novas técnicas de gestão e mudanças na estrutura organizacional.This article makes an evaluation of the technological innovations in the home rectilinear furniture industry at Bento Gonçalves, the main productive agglomeration in Rio Grande do Sul State and one of the most important in Brazil. A descriptive analysis is made using the data obtained trough a questionnaire sent to the industries offices; it concludes that the most important innovations to the industry are: of product, the inclusion of new products to the factory but already present in the market; alterations in the design/style of the furniture; of process, partial technological changes in already existing processes and the adoption of processes that already exist in the sector; and organizational, the implementation of new management techniques and changes in the organizational structure.

  16. Florística e estrutura fitossociológica em floresta ombrófila densa submontana na barragem do rio São Bento, Siderópolis, Estado de Santa Catarina - DOI: 10.4025/actascibiolsci.v31i4.3345 Floristic composition and phytosociological structure in a submontane ombrophilous dense forest at São Bento river dam, Siderópolis, Santa Catarina State - DOI: 10.4025/actascibiolsci.v31i4.3345

    OpenAIRE

    João André Jarenkow; Robson dos Santos; Rafael Martins; Sinara Colonetti; Vanilde Citadini-Zanette; Edilane Rocha

    2009-01-01

    Apresentam-se os resultados de levantamentos florístico e fitossociológico em remanescente de Floresta Ombrófila Densa Submontana circunjacente à barragem do rio São Bento, objetivando fornecer dados primários para ações de restauração e conservação desta formação. A área está localizada no Sul de Santa Catarina, município de Siderópolis. Utilizou-se como área amostral um hectare e foram registrados indivíduos com DAP ≥ 5 cm e quantificados seus descritores estruturais. Foram identificadas 10...

  17. El “Libro de la Guerra” y la traducción de Vegecio por Fray Alfonso de San Cristóbal

    Directory of Open Access Journals (Sweden)

    Roca Barea, María Elvira

    2007-06-01

    Full Text Available

    This article is devoted to the brief and anonymous military treatise socalled Libro de la guerra that was edited in 1916 by Lucas de Torre. Its origin was a mystery until now, but this text is only a resume of a Spanish translation of Vegetius’ Epitome rei militaris that brother Alfonso de San Cristobal did for Enrique III of Castile. I discovered a unknown and never catalogued copy of the Libro de la guerra in the manuscript 9806 (Madrid, Biblioteca Nacional that belonged to the library of the Conde de Haro that help me to do a new and more complete edition and to establish some important data about the Libro de la guerra. The last part of my work is devoted to the knowledge and influence of Vegetius at the end of the Middle Age in Castile.



    Este trabajo se ocupa del breve y anónimo tratado conocido como Libro de la guerra que Lucas de Torre editó en 1916. Su origen ha sido un misterio hasta ahora, pero en realidad este texto no es más que un resumen de la traducción al castellano del Epitome rei militaris que fray Alfonso de San Cristóbal hizo para Enrique III. Descubrí una copia desconocida y no catalogada del Libro de la guerra en el manuscrito 9806 (Madrid, Biblioteca Nacional, el cual perteneció a la biblioteca

  18. Experience with WASP and MAED among IAEA Member States participating in the Regional Co-operative Agreement (RCA) in Asia and the Pacific Region

    International Nuclear Information System (INIS)

    1989-10-01

    The report includes the proceedings and papers presented during the workshop on the experience with WASP/MAED computer programs among IAEA Member States participating in the regional co-operative agreement (RCA) in Asia and the Pacific Region, organized by the IAEA and held in Kuala Lumpur (Malaysia) between 5-9 December 1988. A separate abstract was prepared for each of the 14 papers presented. Refs, figs and tabs

  19. The Text of the Third Agreement to Extend the 1987 Regional Co-operative Agreement for Research, Development and Training related to Nuclear Science and Technology (RCA). Latest Status. Extension of Agreement

    International Nuclear Information System (INIS)

    2002-01-01

    The text of the Third Agreement to Extend the 1987 Regional Co-operative Agreement for Research, Development and Training Related to Nuclear Science and Technology, t he 1987 RCA , is reproduced herein for the information of all Members [es

  20. The Text of the Fifth Agreement to Extend the 1987 Regional Cooperative Agreement for Research, Development and Training Related to Nuclear Science and Technology (RCA). Extension of Agreement. Latest Status

    International Nuclear Information System (INIS)

    2012-01-01

    The Text of the Fifth Agreement to Extend the 1987 Regional Cooperative Agreement for Research, Development and Training Related to Nuclear Science and Technology (RCA). Extension of Agreement. Latest Status [es

  1. The Text of the Fourth Agreement to Extend the 1987 Regional Co-operative Agreement for Research, Development and Training related to Nuclear Science and Technology (RCA). Extension of Agreement. Latest Status

    International Nuclear Information System (INIS)

    2007-01-01

    The text of the Fourth Agreement to Extend the 1987 Regional Co-operative Agreement for Research, Development and Training Related to Nuclear Science and Technology, 'the 1987 RCA', is reproduced herein for the information of all Members [es

  2. The Text of the Fourth Agreement to Extend the 1987 Regional Co-operative Agreement for Research, Development and Training related to Nuclear Science and Technology (RCA). Extension of Agreement. Latest Status

    International Nuclear Information System (INIS)

    2007-01-01

    The text of the Fourth Agreement to Extend the 1987 Regional Co-operative Agreement for Research, Development and Training Related to Nuclear Science and Technology, 'the 1987 RCA', is reproduced herein for the information of all Members

  3. Sebastián Vizcaíno y Fray Antonio de la Ascensión, una nueva etapa en el reconocimiento de las Californias Novohispanas: Estudio socio-histórico

    Directory of Open Access Journals (Sweden)

    Maña Luisa Rodrfguez-Sala

    1995-01-01

    Full Text Available During the second half of the sixteenth century md into the seventeenth, the voyages backed by the Spanish crown give the Spanish control of the route to the East. This document makes an effort to rescue the biographical information of the seafarer and explorer Sebastian Vizcaino, who made two crossings to Upper and Lower Califor­nia. The information was gathered from primary sources such as the Archive General de las Indias (AGI and the Archive General de la Naci6n (AGN, as well as from a number of secondary sources. In addition, using an interdisciplinary socio-historical focus, the details of Vizcaino's voyages have been described, with particular emphasis on the geographical discoveries and the increased scientific knowledge derived from the second trip which Vizcaino and Fray Antonio de la Ascenci6n made to the California.

  4. Florística e estrutura fitossociológica em floresta ombrófila densa submontana na barragem do rio São Bento, Siderópolis, Estado de Santa Catarina - DOI: 10.4025/actascibiolsci.v31i4.3345 Floristic composition and phytosociological structure in a submontane ombrophilous dense forest at São Bento river dam, Siderópolis, Santa Catarina State - DOI: 10.4025/actascibiolsci.v31i4.3345

    Directory of Open Access Journals (Sweden)

    João André Jarenkow

    2009-08-01

    Full Text Available Apresentam-se os resultados de levantamentos florístico e fitossociológico em remanescente de Floresta Ombrófila Densa Submontana circunjacente à barragem do rio São Bento, objetivando fornecer dados primários para ações de restauração e conservação desta formação. A área está localizada no Sul de Santa Catarina, município de Siderópolis. Utilizou-se como área amostral um hectare e foram registrados indivíduos com DAP ≥ 5 cm e quantificados seus descritores estruturais. Foram identificadas 107 espécies, pertencentes a 42 famílias botânicas, totalizando 1.715 indivíduos. As espécies com maiores valores de importância (VI foram Euterpe edulis Mart., Casearia sylvestris Sw. e Bathysa australis (St.-Hil. K. Schum. Entre as espécies identificadas, encontrou-se elevado índice de zoofilia e zoocoria. Pela característica florística e abundância de serapilheira, a área encontra-se em estádio avançado de regeneração naturalAiming to provide primary data to be used in restoration programs, data from a floristic and phytosociological survey at a Submontane Ombrophilous Dense Forest remnant around São Bento river dam (Siderópolis municipality, Santa Catarina State, southern Brazil are presented. All tree individuals with a diameter at breast height (DBH ≥ 5 cm were recorded (1 ha plot. 1,715 individuals belonging to 107 species and 42 botanical families were identified. Euterpe edulis Mart., Casearia sylvestris Sw. and Bathysa australis (St.-Hil. K.Schum. were the species with higher values of structural importance. High index of zoophily and zoochory were registered among the identified species. From the floristic composition and litter abundance, it can be assumed that the studied area corresponds to an advanced stage of natural regeneration

  5. Development of a geographical data base and its utilization in elaboration of maps of environmental sensitivity to the oil spill in the coastal area between Galinhos and Sao Bento do Norte, RN (Brazil); Desenvolvimento de um banco de dados geograficos e sua utilizacao na elaboracao de mapas de sensibilidade ambiental ao derramamento de oleo na area costeira entre Galinhos e Sao Bento do Norte - RN

    Energy Technology Data Exchange (ETDEWEB)

    Castro, Angelica Felix de; Amaro, Venerando Eustaquio; Vital, Helenice; Aloise, Dario Jose [Rio Grande do Norte Univ., Natal, RN (Brazil). Programa de Recursos Humanos da ANP para o Setor Petroleo e Gas, PRH-22. Formacao em Geologia, Geofisica e Informatica

    2003-07-01

    The coastal areas located in the northern coast of the Rio Grande do Norte State, specifically between the districts of Galinhos e Sao Bento do Norte, characterized by constant processes of coastal and eolic transport, causing erosion, alterations in the sediments and modifications in the coast line. Beyond of those natural factors, there is the proximity to Polo Petrolifero of Guamare, the largest terrestrial producer of petroleum of Brazil. The first part of that work consisted of to elaborate and to develop a Geographical Database (BDG), to store all the existent data of the study area, such as geological and geophysical data, hydrodynamic data, products of remote sensing, thematic maps, among others. The second stage of this work aimed to develop starting from the data previously stored in BDG, Oil-Spill Environmental Sensitivity Maps (Maps SAO). Those maps evaluate the reaction of the certain place if to happen an oil spill in her, supplying necessary information to the decision in cleaning and removal of the spilled oil. In that way, Maps SAO of the study area were elaborated in different teams to evaluate if there would be change of the behavior of the coast in the presence of the oil. (author)

  6. PENGURANGAN DEFECT PADA PRODUK SEPATU DENGAN MENGINTEGRASIKAN STATISTICAL PROCESS CONTROL (SPC DAN ROOT CAUSE ANALYSIS (RCA STUDI KASUS PT. XYZ

    Directory of Open Access Journals (Sweden)

    Moch. Teguh Fajrin

    2018-04-01

    Full Text Available PT. XYZ is a foreign capital investment companies are located in one area of town of Sidoarjo which has more than 7000 employees in it and of course want to have a high quality product . PT footwear products. XYZ is the world quality products that promote the quality and comfort of the wearer. Problems that occur in the production process of PT . XYZ of 7 -injection engine that has the most number of engine defect is 5.6 and 7. Quality products at heavily influence the shoe production to consumers. If damaged, then the product can not be distributed to consumers .Therefore , the quality of the shoes must be maintained for the successful marketing of the product. From our previous improvements made in reducing the defect in the production process , but the result is less than optimal , so do research that aims to make improvements again with another method . The method used in this research is to apply the methods of Statistical Processing Control (SPC and Root Cause Analysis (RCA. The results of the check sheet analysis and Pareto diagram can be seen the frequency of product defects (defects over roughing most occurred in March 2016 as many as 345 shoes (62% of the total production of 489 products. Then the second frequency in February 2016 as many as 214 shoes (38% of the total production of 357 products. And from the image Control Chart P can be concluded that the data are in a state of uncontrolled. Because of all these 50 data, there is one data point that is outside the control limits (out of control, on the 4th point the data has a value of the proportion of 1, beyond the limits Upper Control Limit (UCL is equal to 0.938. During the dots located within the boundaries of a controller, a process is under controlled conditions, and no action required. However, one point that lies outside the control limit is interpreted as the fact that the quality control in the production process (injection PT. XYZ uncontrolled or still experiencing

  7. L'amélioration des techniques de transformation du manioc en cossettes en RCA : rouissage en vase clos et séchage en encage thermique

    OpenAIRE

    Rasoanantoandro-Gothard , Marie Céline

    2003-01-01

    International audience; Le manioc constitue l'aliment de base en République centrafricaine (RCA). La population le consomme sous diverses formes: tubercule sans préparation (consommé cuit), chickouangue, bouillie, soupe, grillé ou braisé (roui ou non roui), sous forme de pâte cuite préparée à partir de la farine de cossettes. Plus de 80% de la population centrafricaine consomme le manioc sous forme de pâte cuite préparée à partir de la farine de cossette et plus de 50% des besoins énergétique...

  8. Aplicación de la tribología y el análisis de la causa raíz (RCA en motores de combustión interna. // Application of tribology and root cause analysis (RCA on diesel engine.

    Directory of Open Access Journals (Sweden)

    F. Martínez Pérez

    2008-09-01

    Full Text Available En el trabajo, se hace empleo de la herramienta de trabajo Análisis de la Causa Raíz (RCA para llegar a unas primerasconclusiones acerca de fallos producidos en el nudo tribológico válvula – guía de válvula en un motor de combustióninterna, y así pasar a hallar la causa final y dar solución al problema. El método permite arribar a conclusiones en cuanto ala causa del problema.Palabras claves: Tribología, Análisis causa raíz, RCA, desgaste, motor de combustión interna.______________________________________________________________________________Abstract:It is used the process root cause in the analysis of a problem in the tribological pair valve- valve guide of an internalcombustion engine. Using this process was possible to have the first conclusions in the problem and finally to arriveto a final conclusion about the cause of the problem.Key words: Tribology, RCA, wear, engine.

  9. The pde2 gene of Saccharomyces cerevisiae is allelic to rca1 and encodes a phosphodiesterase which protects the cell from extracellular cAMP.

    Science.gov (United States)

    Wilson, R B; Renault, G; Jacquet, M; Tatchell, K

    1993-07-05

    The high affinity cAMP phosphodiesterase, encoded by PDE2, is an important component of the cAMP-dependent protein kinase signaling system in Saccharomyces cerevisiae. An unexpected phenotype of pde2 mutants is sensitivity to external cAMP. This trait has been found independently for rca1 mutants and has been used to monitor the effects of cAMP on several biological processes. We demonstrate here that RCA1 is identical to PDE2. Further analysis of the phenotype of pde2 deletions reveal that exogenously added cAMP results in an increase in the internal level of cAMP. This increase slows down the rate of cell division by increasing the length of the G1 phase of the cell cycle and leads to increased cell volume. Also, cells with a disrupted PDE2 gene previously arrested by nutrient starvation rapidly lose thermotolerance when incubated with exogenous cAMP. From these observations we propose that a role of the PDE2-encoded phosphodiesterase may be to help insulate the internal cAMP pools from the external environment. This protective role might also be important in other eukaryotic organisms where cAMP is a key second messenger.

  10. Neural cell fate in rca1 and cycA mutants: the roles of intrinsic and extrinsic factors in asymmetric division in the Drosophila central nervous system.

    Science.gov (United States)

    Lear, B C; Skeath, J B; Patel, N H

    1999-11-01

    In the central nervous system (CNS) of Drosophila embryos lacking regulator of cyclin A (rca1) or cyclin A, we observe that several ganglion mother cells (GMCs) fail to divide. Whereas GMCs normally produce two sibling neurons that acquire different fates ('A/B'), non-dividing GMCs differentiate exclusively in the manner of one of their progeny ('B'). In zygotic numb mutants, sibling neuron fate alterations ('A/B' to 'A/A') occur infrequently or do not occur in some sibling pairs; we have determined that depletion of both maternal and zygotic numb causes sibling neurons to acquire equalized fates ('A/A') with near-complete expressivity. In rca1, numb mutant embryos, we observe binary cell fate changes ('B' to 'A') in several GMCs as well. Finally, we have demonstrated that expression of Delta in the mesoderm is sufficient to attain both sibling fates. Our results indicate that the intrinsic determinant Numb is absolutely required to attain differential sibling neuron fates. While the extrinsic factors Notch and Delta are also required to attain both fates, our results indicate that Delta signal can be received from outside the sibling pair.

  11. Estudo de Caso: Análise de um Relatório de Controle Ambiental (RCA Referente à Atividade de Levantamento Sísmico

    Directory of Open Access Journals (Sweden)

    Igor Leonardo Morais Nascimento

    2010-01-01

    Full Text Available Este trabalho aborda a análise de um Relatório de Controle Ambiental (RCA, da atividade de sísmica, submetido à obtenção de licenciamento ambiental junto ao Instituto de Defesa do Meio Ambiente – IDEMA. Realiza uma comparação dos itens exigidos no Termo de Referência (TR do IDEMA com o Estudo ambiental citado, a fim de identificar se todos os itens exigidos legalmente foram contemplados no RCA e se os mesmos estão em conformidade com o Termo. Utiliza a técnica de estudo de impacto ambiental baseado em um contexto legal que estabelece requisitos a serem observados e procedimentos a serem cumpridos, tal técnica é a análise formal da qualidade de um estudo ambiental. Verifica, também, a repetição ou não das principais deficiências apontadas no elemento Mitigação e compensação de impactos com base no estudo do Ministério Público Federal - MPF, a partir da técnica de análise de conteúdo de estudo ambiental.

  12. Direct detection of RNA in vitro and in situ by target-primed RCA: The impact of E. coli RNase III on the detection efficiency of RNA sequences distanced far from the 3'-end.

    Science.gov (United States)

    Merkiene, Egle; Gaidamaviciute, Edita; Riauba, Laurynas; Janulaitis, Arvydas; Lagunavicius, Arunas

    2010-08-01

    We improved the target RNA-primed RCA technique for direct detection and analysis of RNA in vitro and in situ. Previously we showed that the 3' --> 5' single-stranded RNA exonucleolytic activity of Phi29 DNA polymerase converts the target RNA into a primer and uses it for RCA initiation. However, in some cases, the single-stranded RNA exoribonucleolytic activity of the polymerase is hindered by strong double-stranded structures at the 3'-end of target RNAs. We demonstrate that in such hampered cases, the double-stranded RNA-specific Escherichia coli RNase III efficiently assists Phi29 DNA polymerase in converting the target RNA into a primer. These observations extend the target RNA-primed RCA possibilities to test RNA sequences distanced far from the 3'-end and customize this technique for the inner RNA sequence analysis.

  13. Analysis of the N-glycosylation of the serum glycoproteins defined by Con A, PHA-E, RCA1 and WGA in Chinese patients with gastrointestinal diseases.

    Science.gov (United States)

    Zhang, J; Chen, Y; Dai, X; Wang, S

    1996-03-01

    Glycoproteins from tumor cells isolated by Con A, PHA-E and RCA1, were coupled to horse radish peroxidase and then used as reporters to evaluate the oligosaccharides change on serum glycoproteins in digestive tract diseases and individual healthy persons. A value 2 standard deviation above the mean of the healthy person group was considered positive. The results indicated that the positive rates of the oligosaccharides bound with Con A, PHA-E and RCA1 were 51% (61/119), 70.6% (84/119), and 76.4% (91/119) in patients with gastric cancer; 53.3% (16/30), 46.7% (14/30) and 66.7% (20/30) in esophageal cancers; 28.5% (15/49), 49.0% (24/49) and 46.9% (23/49) in colorectal cancer; 78.1% (25/32), 81.3% (26/32) and 31.3% (10/32) in gallbladder tumors; 60.4% (29/48), 54.1% (26/48) and 39.5% (19/48) in hepatocellular cancer. The positive rates among the patients with benign diseases were also found to be 12.7% (16/126), 15.5% (20/126) and 26.2% (33/126). However, the expression of the oligosaccharide moieties recognized by WGA on the glycoprotein bound with Con A, was significantly lower in the serum of patients with tumors than in those with benign disease and in healthy individuals (P < 0.01, P < 0.01).

  14. Geological map of Uruguay Esc 1,100,000. Carmelo Sheet P-24

    International Nuclear Information System (INIS)

    Ferrando, L; Eugui, W; Cabrera, Z; Elias, R

    1990-01-01

    This work is about the geological map of Uruguay Esc.1.100.000 (Carmelo) and the explanatory memoranda which describes the geological , lithological and sedimentological characteristics soils of the precambrian period in the Mercedes , Fray Bentos, Libertad and Raigon formations. The Precambrian rocks are found in large quarries in Carmelo hill

  15. Geological map of Uruguay Esc 1,100,000. Molles Sheet K-19

    International Nuclear Information System (INIS)

    Ford, I

    1990-01-01

    This work is about the geological map of Uruguay Esc.1.100.000 (Molles) and the explanatory memoranda which describes the geological , lithological and sedimentological characteristics soils belong to the Cretaceous, Tertiary and Quaternary period in Arapey, Mercedes, Asencio, Palmitas, Fray Bentos and Libertad formations

  16. Geological map of Uruguay Esc 1,100,000. Bequelo Sheet N0-20

    International Nuclear Information System (INIS)

    Montana, J.; Ford, I.; Morales, H.

    1990-01-01

    This work is about the geological map of Uruguay Esc.1.100.000 (Bequelo) and the explanatory memoranda which describes the geological , lithological and sedimentological characteristics of the precambrian period in the Bequelo stream as well as the Mercedes , Asencio and Fray Bentos formations

  17. Geological map of Uruguay Esc 1,100,000. Bizcocho Sheet N-0-21

    International Nuclear Information System (INIS)

    Ford, I; Gancio, F

    1990-01-01

    This work is about the geological map of Uruguay Esc.1.100.000 (Bizcocho) and the explanatory memoranda which describes the geological , lithological and sedimentological characteristics of the lower Proterozoic in the socket of the La Plata river, Upper Cretaceous in Mercedes and Asencio formations, lower Tertiary in Palmitas and Fray Bentos formations and soils characteristics of the Quaternary period

  18. Geological map of Uruguay scale 1.100.000 Canada Nieto Sheet P-23

    International Nuclear Information System (INIS)

    Ferrando, L; Eugui, W; Cabrera, Z; Elias, R

    1990-01-01

    This work is about the geological map of Uruguay Esc.1.100.000 (Canada Nieto) and the explanatory memoranda which describes the geological , lithological and sedimentological characteristics soils of the pre devoniam period in the Mercedes , Asencio and Fray Bentos formations

  19. Geological map of Uruguay Esc 1,100,000. El Ombu Sheet N-18

    International Nuclear Information System (INIS)

    Ford, I

    1990-01-01

    This work is about the geological map of Uruguay Esc.1.100.000 (El Ombu) and the explanatory memoranda which describes the geological , lithological and sedimentological characteristics soils belong to the Cretaceous, Tertiary and Quaternary period in Arapey, Mercedes, Asencio, Palmitas, Fray Bentos and Libertad formations

  20. Geological map of Uruguay scale 1,100,000. Agraciada Sheet R-23, Nueva Palmira Sheet R- 24

    International Nuclear Information System (INIS)

    Ferrando, L.; Eugui, W.; Cabrera, Z.; Elias, R.

    1990-01-01

    This work is about the geological map of Uruguay Esc.1.100.000 (Agraciada and Nueva Palmira) and the explanatory memoranda which describes the geological , lithological and sedimentological soil characteristics of: Fray Bentos, Camacho, Raygon, Libertad and Villa Soriano formations

  1. Translations on Telecommunications Policy, Research and Development, Number 53

    Science.gov (United States)

    1978-09-14

    Aguada, and provision of new service in housing complexes such as Parque Posadas, Carbe Aguada and Zapican. IDB Contract One of the milestones...Paysandu, Salto, La Paz, Fray Bentos, Maldonado, Peninsula, La Barra de Maldonado and Young; work began on networks for Parque del Plata, Salinas

  2. Geological map of Uruguay Esc 1,100,000. Algorta Sheet N-16

    International Nuclear Information System (INIS)

    Ford, I; Gancio, F

    1990-01-01

    This work is about the geological map of Uruguay Esc.1.100.000 (Algorta) and the explanatory memoranda which describes the geological , lithological and sedimentological soil characteristics of the upper cretaceous in Guichon, Mercedes and Asencio formaltions as well as the lower tertiary period of Palmitas and Fray Bentos formations

  3. Geological map of Uruguay Esc 1,100,000. Palmitas Sheet 0- 22

    International Nuclear Information System (INIS)

    Ford, I.; Gancio, F

    1990-01-01

    This work is about the geological map of Uruguay Esc.1.100.000 (Molles) and the explanatory memoranda which describes the geological , lithological and sedimentological characteristics soils belong to the Proterozoic, Cretaceous, Tertiary and Quaternary period in Mercedes, Asencio, Palmitas and Fray Bentos formations

  4. Geological map of Uruguay Esc 1,100,000. Paso del Palmar Sheet N-19

    International Nuclear Information System (INIS)

    Ford, I.; Montana, J.; Morales, H.

    1990-01-01

    This work is about the geological map of Uruguay Esc.1.100.000 (Paso del Palmar) and the explanatory memoranda which describes the geological , lithological and sedimentological characteristics soils belong to Cretaceous, Tertiary and Quaternary period in San Gregorio, Arapey, Mercedes, Asencio and Fray Bentos formations

  5. The text of the third agreement to extend the 1987 Regional Co-operative Agreement for Research, Development and Training Related to Nuclear Science and Technology (RCA). Extension of agreement

    International Nuclear Information System (INIS)

    2002-01-01

    The text of the Third Agreement to Extend the 1987 Regional Co-operative Agreement for Research, Development and Training Related to Nuclear Science and Technology, 'the 1987 RCA', is reproduced herein for the information of all Members. Pursuant to Article 1 of the Third Agreement to Extend the 1987 Regional Co-operative Agreement, the 1987 RCA shall continue in force for a further period of five years with effect from 12 June 2002, i.e., through 11 June 2007. As of 15 May 2002, notifications of acceptance had been received by the Director General from the Governments of Bangladesh, China, India, Indonesia, Republic of Korea, Malaysia, Pakistan, Sri Lanka and Viet Nam. The latest status list is attached

  6. Frayed careers: exploring rhythms of working lives

    NARCIS (Netherlands)

    Sabelis, I.H.J.; Schilling, E.

    2013-01-01

    In studies on difference related to age and gender, we face 'abnormal' or 'typical' work-life arrangements vis-à-vis taken-for-granted career concepts. Age and career are conceptualized from different angles depending on politics of work and organization, societal perspectives of age group position,

  7. Above the fray in environmental management

    International Nuclear Information System (INIS)

    Mullin, R.

    1993-01-01

    Despite a generally disappointing performance in the environmental management sector last year, companies in the water treatment business are still held in high regard by Wall Street. The $2.9-billion US market grew 8% last year, and a 6%-8% advance is forecast for the next few years, although discretionary environmental management projects are expected to lag the recovery. Growth is driven largely by the sheer volume of water used in the US-42.3 billion gal/day or 168 gal/day, per capita, with heavy industries using up to 1,000 gal/minute-and the proliferation of regulations affecting water treatment. Recent regulations include the Safe Water Drinking Act, the Resource Conservation and Recovery Act ban on landfilling hazardous wastes, and the ban on ocean dumping of municipal waste. The Clean Water Act of 1987 is scheduled to be reauthorized this year, but final rulings are not expected until mid-1994. Among the probable new rules are control and treatment of municipal and farm storm waters and runoff, treatment of contaminated sediments, toxics use reduction targets, a nationwide (rather than state-by-state) ban on phosphate detergents, nationwide standardization of water quality criteria, and further protection for wetlands. From water supply through processing, power generation, and eventual discharge, water treatment firms are now positioning themselves as environmental leaders, stewards who can lead industry into an environmentally correct future. Despite some differences in organization, basic strategies seem to be the same among top firms, where the trend is to meld all customers' needs into a single program of analysis, design, delivery, and monitoring

  8. O Papa precisa do marxismo? Bento XVI e a incompatibilidade entre a fé cristã e a fé marxista (Does Pope need of Marxism? Benedict XVI and the incompatibility between the Christian faith and the Marxist faith

    Directory of Open Access Journals (Sweden)

    Rudy Albino Assunção

    2012-10-01

    Full Text Available O marxismo aparece insistentemente na teologia e no magistério de Joseph Ratzinger-Bento XVI como um inimigo permanente ao qual o cristianismo deve se contrapor, sem possibilidades de conciliação entre ambos. Mas qual concepção subjaz essa rejeição tão peremptória, tão decidida? Para alcançarmos a resposta a tal questão, aprofundamos a visão de Joseph Ratzinger a partir de alguns de seus escritos teológicos (anteriores ao pontificado e, em seguida, nas suas três encíclicas, o ponto alto de seu magistério papal (Deus caritas est, Spe salvi e Caritas in veritate. Defendemos que a crítica de Bento XVI, antes de ser exclusivamente teológica (ou doutrinária, é filosófica, baseada na racionalidade e não na fé professada pela Igreja, que lhe permite tratar o marxismo não simplesmente como um programa político que vai contra alguns valores cristãos, mas como uma escatologia judaico-cristã secularizada, um messianismo político, portanto, como uma religião, como uma fé, que nega e esvazia o núcleo essencial da fé cristã. E aqui está a raiz da sua oposição. Palavras-chave: Marxismo. Bento XVI. Messianismo. Escatologia política.   Abstract: Marxism appears repeatedly in Pope Benedict’s theology and teaching as a permanent enemy that Christianity must oppose without any possibilities of conciliation between them. However, what underlies this decisive rejection? To answer this question we look further into Joseph Ratzinger’s perspective starting with some of his theological writings (before the pontificate followed by three of his encyclicals, the high point of his papal teaching (Deus caritas est, Spe salvi e Caritas in veritate. We argue that Benedict XVI's criticism, prior to being purely theological (or doctrinal, is philosophical, based on rationality and not in the faith professed by the Church, allowing him to treat marxism not simply as a political program that goes against some Christian values

  9. RCA annual report 1996. Draft

    International Nuclear Information System (INIS)

    1997-02-01

    In accordance with Article VII.4 of the Regional Co-operative Agreement for Research, Development and Training Related to Nuclear Science and Technology 1987 and extended in 1992, a draft report of activities for the calendar year 1996 is submitted

  10. Aplicación de la tribología y el análisis de la causa raíz (RCA en motores de combustión interna.

    Directory of Open Access Journals (Sweden)

    F. Martínez Pérez

    2008-09-01

    Full Text Available En el trabajo, se hace empleo de la herramienta de trabajo Análisis de la Causa Raíz (RCA para llegar a unas primeras conclusiones acerca de fallos producidos en el nudo tribológico válvula – guía de válvula en un motor de combustión interna, y así pasar a hallar la causa final y dar solución al problema. El método permite arribar a conclusiones en cuanto a la causa del problema.Application of tribology and root cause analysis (RCA on diesel engine.It is used the process root cause in the analysis of a problem in the tribological pair valve- valve guide of an internal combustion engine. Using this process was possible to have the first conclusions in the problem and finally to arrive to a final conclusion about the cause of the problem.

  11. Recycled concrete aggregate (RCA) for infrastructure elements.

    Science.gov (United States)

    2014-07-01

    With a growing demand for new construction and the need to replace infrastructure stretched beyond its service life, society faces the : problem of an ever-growing production of construction and demolition waste. The Federal Highway Administration (F...

  12. Fraying at the Edges: UK Surrogacy Law in 2015.

    Science.gov (United States)

    Horsey, Kirsty

    2016-11-01

    This commentary examines a series of high-profile surrogacy cases decided in 2015. Taken singly or together, these cases serve to illustrate how the UK's law on surrogacy—in particular its provisions regarding eligibility for parental orders—is not only out of date but also becoming nonsensical. These problems culminate in an evident inability of the law to protect the best interests of children born through surrogacy and indicate strongly a need for reform.

  13. Selection and Breeding of Cattle in Asia: Strategies and Criteria for Improved Breeding. Prepared under the Framework of an RCA Project with the Technical Support of the Joint FAO/IAEA Programme of Nuclear Techniques in Food and Agriculture

    International Nuclear Information System (INIS)

    2009-10-01

    The International Atomic Energy Agency (IAEA) and the Regional Cooperative Agreement for Asia and the Pacific Region (RCA), with the technical support of the Joint FAO/IAEA Programme of Nuclear Techniques in Food and Agriculture, implemented a Technical Cooperation (TC) project entitled Integrated Approach for Improving Livestock Production Using Indigenous Resources and Conserving the Environment (RAS/5/044). The 23 project counterparts and the IAEA technical officer, based on the lack of standard practices in the region with regard to selection of cattle for breeding purposes, and the need to properly manage the genetic resources within each country for improving the productivity of the existing stock while maintaining the unique and beneficial genetic characteristics of the indigenous breeds, agreed during the first meeting to request the IAEA to recruit a group of experts with the task of preparing guidelines for the selection and breeding of cattle and buffalo on the Asian continent. To address these recommendations, an experts meeting on Selection Criteria for Breeding Heifers was organized and held in Mymensingh, Bangladesh. The meeting was hosted by the Faculty of Veterinary Science of the Bangladesh Agricultural University (BAU) from 6 to 10 February 2006. It was attended by six foreign experts and two local experts, and was supported by the technical officer of RAS/5/044. The experts from countries participating in RAS/5/044 gave presentations on the current state of cattle breeding in their countries and two experts working in industrialized countries within the region (New Zealand and Australia) informed the participants about the existing cattle breeding programmes in their respective countries and offered their perspectives on how similar approaches could be transferred to the Member States participating in RAS/5/044. All experts also made a field visit to a prominent dairy-producing region, to experience at first-hand some of the current programmes

  14. Guidelines for sustainable manure management in Asian livestock production systems. A publication prepared under the framework of the RCA project on Integrated Approach for Improving Livestock Production Using Indigenous Resources and Conserving the Environment

    International Nuclear Information System (INIS)

    2008-05-01

    The International Atomic Energy Agency (IAEA) and the Regional Cooperative Agreement for Asia and the Pacific Region (RCA), with the technical support of the Joint FAO/IAEA Programme of Nuclear Techniques in Food and Agriculture, implemented a Technical Cooperation (TC) project entitled 'Integrated approach for improving livestock production using indigenous resources and conserving the environment' (RAS/5/044). Technical Cooperation projects are technology transfer initiatives, designed to address specific priorities identified by Member States. The specific objectives of this project were: (a) to improve animal productivity and decrease discharges of selected greenhouse gases, (methane and carbon dioxide) and selected nutrients (nitrogen and phosphorus) into the environment; and (b) to identify and adopt better breeding strategies to improve animal productivity through the use of better selection criteria for offspring from cross-breeding programmes, optimum utilization of appropriate indigenous cows, benchmarking for growth and reproduction, and improving procedures for management, nutrition and healthcare programmes in dairy farms. The first meeting to plan project activities was hosted by the Institute of Agricultural Environment and Sustainable Development of the Chinese Academy of Agricultural Sciences (CAAS), Beijing, and was held from 4 to 8 April 2005. It was attended by 23 nominated project counterparts from 12 RCA Member States and was supported by three IAEA experts. One of the conclusions from this meeting was that there was considerable scope and need for improving current manure management practices in the region to enhance the productive recycling of ingested nutrients in animal production systems, which in addition to increasing livestock and crop productivity will decrease environment pollution. It was agreed that there was a need to focus on improving the nutritional and manure management in integrated livestock systems, and that it was

  15. “Del puente a las huertas comunitarias”: transformaciones socio productivas en las huertas comunitarias de los centros de salud de Gualeguaychú a cinco años del conflicto

    OpenAIRE

    Rosselot, Valeria; Carricart, Pedro

    2015-01-01

    La instalación de una fábrica de celulosa en noviembre 2007 en Fray Bentos, desencadenó en Gualeguaychú, Entre Ríos, uno de los conflictos sociales ambientales más importantes de Latino América. A cinco años del conflicto se analiza el impacto de la protesta social sobre la actividad en diez huertas comunitarias que funcionan en los centros de salud municipales. La hipótesis planteada es que se logra distinto nivel de impacto según el tipo de relaciones logradas (vertical, horizontal o en red...

  16. Improving artificial breeding of cattle and buffalo in Asia. Guidelines and recommendations. A manual prepared under the framework of an IAEA Technical Cooperation Regional RCA Project on 'Improving Animal Productivity and Reproductive Efficiency', with technical support of the Joint FAO/IAEA Division of Nuclear Techniques in Food and Agriculture

    International Nuclear Information System (INIS)

    2005-11-01

    The International Atomic Energy Agency (IAEA) and the Regional Cooperative Agreement for Asia and the Pacific Region (RCA), with technical support of the Joint FAO/IAEA Programme of Nuclear Techniques in Food and Agriculture, implemented a Technical Cooperation (TC) project entitled Improving Animal Productivity and Reproductive Efficiency. The dual objectives of this project are (a) strengthening and extending the field applications of Urea Molasses Multinutrient Blocks (UMMB) and other feed supplementation strategies, and (b) monitoring and improving the reproductive management and fertility of smallholder dairy cattle subjected to Artificial Insemination (AI). The radioimmunoassay (RIA) for measurement of progesterone in milk and use of the computer database AIDA (Artificial Insemination Database Application) play important roles in the success of the latter objective. The first meeting to plan project activities was held in January 1999 in Yangon, Myanmar and the second meeting to review progress and develop further work plans was held in February 2000 in Kuala Lumpur, Malaysia. The latter meeting concluded that the procedures currently used by different Asian countries for evaluation of breeding bulls should be standardized and unified protocols developed for ensuring quality control of semen during processing, storage and field use. It was recommended that this should be accomplished through a regional workshop of national consultants. A workshop of national consultants from 10 RCA Member States was therefore held in April 2002 in Faisalabad, Pakistan, to consider and discuss the following aspects and arrive at a consensus on the best procedures and practices to be adopted to suit conditions and needs in developing countries of Asia: - Selection, management and health control of AI bulls; - Semen technologies from collection through processing to storage; - Delivery and follow-up of field AI services to farmers The IAEA has also supported a similar project in

  17. Improving animal productivity by supplementary feeding of multi-nutrient blocks, controlling internal parasites and enhancing utilization of alternate feed resources. A publication prepared under the framework of an RCA with technical support of the Joint FAO/IAEA Programme of Nuclear Techniques in Food and Agriculture

    International Nuclear Information System (INIS)

    2006-12-01

    countries generally encounter another principal constraint: health. Of the health constraints, bacterial and viral diseases can be successfully controlled through conventional vaccination and quarantine procedures. However, for parasitic disease, these approaches are either not yet possible or impractical, and chemotherapy, coupled with grazing management, are the only methods of control method currently available. In developing countries, the losses induced by clinical and subclinical parasite infections have been estimated to equal the value of the present output of ruminant industries, therefore improved control has the potential to yield considerable productivity benefits. The RCA (Regional Cooperation Agreement for the Asia and Pacific Region) project, RAS/5/035 entitled Improving Animal Productivity and Reproductive Efficiency was initiated in 1999 to assist RCA Member States to improve animal productivity and reproductive efficiency. This project had two components: animal nutrition, and animal reproduction. The animal nutrition component focused on: (i) developing and feeding of urea-molasses multinutrient blocks to supply nutrients deficient in crop residues and forages; (ii) using the ureamolasses multinitrient blocks for the delivery of anthelmintic medication to control gastrointestinal nematode parasitism; and (iii) enhancing efficiency of utilization of feed resources which are locally available and for which humans are not competing with livestock for food. The present publication presents results on these three aspects obtained by the participating groups from the RCA Member States and presented at the Final Review Meeting of the project held in October 2004 in Bangkok, Thailand. This publication is a good source of reference for research workers, students and extension workers alike. It will help promote efficient utilization of feed resources and enhance animal productivity to meet the challenges imposed by the 'Livestock Revolution' taking place in

  18. Endothelial Dysfunction in Resuscitated Cardiac Arrest (ENDO-RCA)

    DEFF Research Database (Denmark)

    Meyer, Anna Sina P; Ostrowski, Sisse Rye; Kjærgaard, Jesper

    2016-01-01

    BACKGROUND: Morbidity and mortality following initial survival of cardiac arrest remain high despite great efforts to improve resuscitation techniques and post-resuscitation care, in part due to the ischemia-reperfusion injury secondary to the restoration of the blood circulation. Patients resusc...

  19. Ecología química en el bentos antártico

    OpenAIRE

    Ballesteros, Manuel (Ballesteros Vázquez); Núñez Pons, Laura; Vázquez, J.; Cristobo, F.J.; Taboada Moreno, Sergio; Figuerola Balañá, Blanca; Ávila Escartín, Conxita

    2011-01-01

    El estudio de las interacciones entre los organismos mediadas por sustancias químicas, lo que se denomina ecología química, nos da información sobre la biología de las especies implicadas, el funcionamiento de la comunidad en que viven y nos puede proporcionar además el conocimiento de nuevas sustancias que pueden ser útiles para el ser humano. En el marco de nuestros estudios sobre la ecología química de los invertebrados antárticos, en el proyecto ECOQUIM (2003-2006) se recolectaron numeros...

  20. Staying above the Fray: Framing and Conflict in the Coverage of Education Policy Debates

    Science.gov (United States)

    Tamir, Eran; Davidson, Roei

    2011-01-01

    This article examines the mass media's role in shaping education policy debates in light of pluralist theory and Bourdieu's social fields theory. We content analyzed the coverage of New Jersey education policy debates during 1985, when the governor moved to consolidate his power in the education field. We used quantitative framing and conflict…

  1. In search of low cost titanium: the Fray Farthing Chen (FFC) Cambridge process

    CSIR Research Space (South Africa)

    Oosthuizen, SJ

    2010-10-01

    Full Text Available delivering a sponge product, aimed at replacing Kroll sponge alone, does not have potential for large reduction in overall titanium cost. Significant cost savings can only be achieved by also reducing the large number of process steps required to process... the sponge to mill product, including sponge purification, comminution, electrode forming, Vacuum Arc Re-melting, Hot and cold rolling. Presently, economy of scale in the production of titanium dictates that it is most cost effective to cast the largest...

  2. In search of low cost titanium: the fray farthing chen (FFC) cambridge process

    CSIR Research Space (South Africa)

    Oosthuizen, SJ

    2011-03-01

    Full Text Available delivering a sponge product, aimed at replacing Kroll sponge alone, does not have potential for large reduction in overall titanium cost. Significant cost savings can be achieved only by also reducing the large number of process steps required... to process the sponge to mill product, including sponge purification, comminution, electrode forming, vacuum arc re-melting, and hot and cold rolling. Presently, economy of scale in the production of titanium dictates that it is most cost...

  3. Entering the Fray: The Role of Outdoor Education in Providing Nature-Based Experiences that Matter

    Science.gov (United States)

    Nicol, Robbie

    2014-01-01

    This article draws on different bodies of knowledge in order to review the potential role of outdoor education in providing nature-based experiences that might contribute to sustainable living. A pragmatic perspective is adopted to critique what outdoor education is, and then what it might be. Phenomenology is used to challenge the belief that…

  4. Base Pair Fraying in Molecular Dynamics Simulations of DNA and RNA

    Czech Academy of Sciences Publication Activity Database

    Zgarbová, M.; Otyepka, Michal; Šponer, Jiří; Lankaš, Filip; Jurečka, P.

    2014-01-01

    Roč. 10, č. 8 (2014), s. 3177-3189 ISSN 1549-9618 Grant - others:GA ČR(CZ) GP14-29874P Institutional support: RVO:68081707 ; RVO:61388963 Keywords : QUANTUM-CHEMICAL COMPUTATIONS * NUCLEIC-ACID STRUCTURES * AMBER FORCE-FIELD Subject RIV: BO - Biophysics; CC - Organic Chemistry (UOCHB-X) Impact factor: 5.498, year: 2014

  5. Fray Tomás de Torquemada, iconógrafo y promotor de las artes

    Directory of Open Access Journals (Sweden)

    Caballero Escamilla, Sonia

    2009-03-01

    Full Text Available In this study the author analyses the Inquisitor Torquemada’s role in two Dominican foundations: the monasteries of Santo Tomás in Ávila and Santa Cruz in Segovia. The historical context in which they emerged and their association with inquisitorial activities converted them into ideal supports for a message designed by this Dominican friar for the purpose of conveying the prestige of the Order and the involvement of the Monarchy in the struggle against heretics. He used the arts to convey a propagandistic message, adapting older iconographic formulas to his current needs, aimed at promoting the expulsion of the Jews.

    En este trabajo se analiza la ascendencia del inquisidor Torquemada sobre dos fundaciones, el convento de Santo Tomás de Ávila y el de Santa Cruz de Segovia. El contexto histórico en el que surgen y su vinculación con la actividad inquisitorial las convierte en soportes de un mensaje hábilmente diseñado por el fraile dominico en el que pone de manifiesto el prestigio de la Orden de Santo Domingo y la implicación de la Monarquía en la lucha antiherética. Aprovechando la eficacia propagandística del lenguaje plástico, no dudará en acudir a fórmulas iconográficas del pasado adaptándolas a su momento presente, creando el caldo de cultivo necesario para lograr su objetivo, la expulsión de los judíos.

  6. Rituals in Death and Dying: Modern Medical Technologies Enter the Fray

    Directory of Open Access Journals (Sweden)

    Michael Gordon

    2015-01-01

    Full Text Available In the absence of immortality, the human species has over the millennia developed rites and rituals to help in the passing of life to honor the person who is dying or has died or in some way demonstrate their “courage” and perseverance as well as duty even in the face of almost certain death. The centuries-old traditions of the gathering of loved ones, the chanting of prayers, the ritual religious blessings are in the process of being replaced by the “miracles” of modern medical technology.

  7. F--Ray: A new algorithm for efficient transport of ionizing radiation

    Science.gov (United States)

    Mao, Yi; Zhang, J.; Wandelt, B. D.; Shapiro, P. R.; Iliev, I. T.

    2014-04-01

    We present a new algorithm for the 3D transport of ionizing radiation, called F2-Ray (Fast Fourier Ray-tracing method). The transfer of ionizing radiation with long mean free path in diffuse intergalactic gas poses a special challenge to standard numerical methods which transport the radiation in position space. Standard methods usually trace each individual ray until it is fully absorbed by the intervening gas. If the mean free path is long, the computational cost and memory load are likely to be prohibitive. We have developed an algorithm that overcomes these limitations and is, therefore, significantly more efficient. The method calculates the transfer of radiation collectively, using the Fast Fourier Transform to convert radiation between position and Fourier spaces, so the computational cost will not increase with the number of ionizing sources. The method also automatically combines parallel rays with the same frequency at the same grid cell, thereby minimizing the memory requirement. The method is explicitly photon-conserving, i.e. the depletion of ionizing photons is guaranteed to equal the photoionizations they caused, and explicitly obeys the periodic boundary condition, i.e. the escape of ionizing photons from one side of a simulation volume is guaranteed to be compensated by emitting the same amount of photons into the volume through the opposite side. Together, these features make it possible to numerically simulate the transfer of ionizing photons more efficiently than previous methods. Since ionizing radiation such as the X-ray is responsible for heating the intergalactic gas when first stars and quasars form at high redshifts, our method can be applied to simulate thermal distribution, in addition to cosmic reionization, in three-dimensional inhomogeneous cosmological density field.

  8. "Frayed All Over:" the Causes and Consequences of Activist Burnout among Social Justice Education Activists

    Science.gov (United States)

    Gorski, Paul C.; Chen, Cher

    2015-01-01

    Despite the growing body of scholarship on burnout among social justice activists who are working on a variety of issues, from labor rights to queer justice, little attention has been paid to burnout among those whose activism focuses on issues of educational justice. To begin to address this omission and understand what supports might help social…

  9. Just Above the Fray - Interpretive Social Criticism and the Ends of Social Justice

    OpenAIRE

    Andrew Gibson

    2008-01-01

    The article lays down the broad strokes of an interpretive approach to social criticism. In developing this approach, the author stresses the importance of both a pluralistic notion of social justice and a rich ideal of personal growth. While objecting to one-dimensional conceptions of social justice centering on legal equality, the author develops the idea of there being multiple "spheres of justice", including the spheres of "care" and "merit". Each of these spheres, he argues, is subject t...

  10. Un discurso latinoamericano y latinoamericanista sobre los recursos naturales en el "caso papeleras"

    Directory of Open Access Journals (Sweden)

    Ana María Vara

    2014-04-01

      This article focuses on a particular aspect, on a discursive level, of the so called "papeleras case", that is the environmental controversy on the border between Uruguay and Argentina due to the projected siting of two pulp mills at the Uruguayan city of Fray Bentos, initiated in 2003. We argue that one of the discursive elements that made possible the continued participation of Uruguayan actors in the transnational advocacy network in this case, even at moments of great bi-national tension, was a Latin American, anti-imperialist collective action framework that echoes a discourse emerged in the early twentieth century in the region; which in turn, works here as a master frame. This discourse may be characterized as a neocolonial counter-discourse of natural resources, and as a proto-environmentalist discourse originated in Latin America.

  11. Evaluación ecotoxicológica de sedimentos en una zona del Río Uruguay, con puntos finales indicadores de toxicidad aguda, sub-letal, crónica, reproductiva y teratogénica

    Directory of Open Access Journals (Sweden)

    Diana Míguez Carames

    2011-05-01

    Full Text Available El objetivo de este trabajo fue caracterizar la toxicidad de los sedimentos de una zona del Río Uruguay, aplicando una batería de bioensayos. Las muestras provinieron de: una zona de influencia de descargas domésticas y efluentes de una planta de celulosa (Fray Bentos, una ciudad turística aguas abajo (Las Cañas y otra aguas arriba (Nuevo Berlín, sin influencia directa de dichos vertidos. Los bioensayos aplicados en elutriados fueron: de toxicidad con Photobacterium leiognathi, de reproducción con Ceriodaphnia dubia, de teratogenicidad y letalidad con Pimephales promelas y el ensayo sub-letal en sedimento completo con Hyalella curvispina. Para evaluar la biodisponibilidad y las rutas de toxicidad, se midió el fraccionamiento del 2,4,5-triclorofenol, con resultados: 63% disuelto, 27% adsorbido sobre partículas y el resto sedimentado.Se observó toxicidad por orgánicos y metales con P. leioghnati para todos los sitios. La frecuencia de malformaciones vertebralesde P. promelas fue de 3.3% en Fray Bentos, pero C. dubia sólo mostró efectos en Nuevo Berlín y Las Cañas. Los efectos con H. curvispina se evidenciaron en todas las muestras. Las rutas de toxicidad incluirían la ingestión de contaminantes disueltos y particulados asociados a arcillas y limo. El vínculo causa-efecto para la toxicidad se continuará investigando.

  12. Antônio, Bento e Domingos: paternidade na elite farroupilha (1835-1845 = Antônio, Bento and Domingos: fatherhood among the farroupilha’s elite (1835-1845

    Directory of Open Access Journals (Sweden)

    Barbosa, Carla Adriana da Silva

    2017-01-01

    Full Text Available Num contexto marcado pela guerra e preponderância das imagens masculinas, a figura paterna representava a segurança corporal e simbólica das famílias da elite farroupilha. Neste artigo, analiso as manifestações de paternidade nas correspondências pertencentes a este grupo, como as escolhas para a educação e o legado a ser herdado por seus filhos

  13. Hábitos alimentares e fatores de risco para aterosclerose em estudantes de Bento Gonçalves (RS) Dietary habits and risk factors for atherosclerosis in students from Bento Gonçalves (state of Rio Grande do Sul)

    OpenAIRE

    Hosana Maria Speranza Cimadon; Renata Geremia; Lucia Campos Pellanda

    2010-01-01

    FUNDAMENTO: A doença cardiovascular aterosclerótica inicia seu processo na infância precoce e é influenciada ao longo da vida por fatores genéticos e exposição ambiental a fatores de risco potencialmente modificáveis. OBJETIVO: Investigar a prevalência de fatores de risco para aterosclerose com ênfase nos hábitos alimentares em uma cidade de colonização predominantemente italiana. MÉTODOS: Estudo transversal de base populacional, envolvendo 590 estudantes do ensino fundamental com idades entr...

  14. Hábitos alimentares e fatores de risco para aterosclerose em estudantes de Bento Gonçalves (RS Dietary habits and risk factors for atherosclerosis in students from Bento Gonçalves (state of Rio Grande do Sul

    Directory of Open Access Journals (Sweden)

    Hosana Maria Speranza Cimadon

    2010-08-01

    Full Text Available FUNDAMENTO: A doença cardiovascular aterosclerótica inicia seu processo na infância precoce e é influenciada ao longo da vida por fatores genéticos e exposição ambiental a fatores de risco potencialmente modificáveis. OBJETIVO: Investigar a prevalência de fatores de risco para aterosclerose com ênfase nos hábitos alimentares em uma cidade de colonização predominantemente italiana. MÉTODOS: Estudo transversal de base populacional, envolvendo 590 estudantes do ensino fundamental com idades entre 9 e 18 anos, com amostra por conglomerado. Foram coletados: dados de identificação, história familiar e história pregressa, além das informações referentes à alimentação dos estudantes. Os hábitos alimentares considerados inadequados incluíram: consumo de fast food, guloseimas, bebidas açucaradas e gorduras de origem animal por quatro ou mais vezes por semana e frutas, hortaliças e leguminosas por menos de quatro vezes por semana. RESULTADOS: A prevalência de excesso de peso entre os estudantes foi 24,6% (n=145; pressão arterial elevada, 11,1% (n=65; tabagismo passivo, 35,4% (n=208; estilo de vida sedentário, 52,3% (n=306; história familiar doenças 1º grau: hipertensão arterial sistêmica, 21,4% e obesidade, 36,5%. Alimentos consumidos por quatro ou mais vezes por semana: fast food, 70,3% (n=411; guloseimas, 42,7% (n=252; bebidas açucaradas, 71% (n=419; e gorduras de origem animal, 24,4% (n=143. Alimentos consumidos por menos de quatro vezes por semana: frutas, 36,8% (n=215; hortaliças, 49,5% (n= 292 e leguminosas, 63,7% (n=374. CONCLUSÃO: São necessárias intervenções que promovam mudanças nos hábitos alimentares dos estudantes: maior consumo de frutas, hortaliças e leguminosas e aumento do nível de atividade física.BACKGROUND: Atherosclerotic cardiovascular disease begins its process in early childhood and is influenced throughout life by genetic factors and environmental exposure to potentially modifiable risk factors. OBJECTIVE: To investigate the prevalence of risk factors for atherosclerosis with emphasis on dietary habits in a predominantly Italian colonization town. METHODS: Population-based cross sectional study, involving 590 primary school students aged between 9 and 18 years, with a cluster sample. The following were collected: identification data, family history and personal history, and information regarding students' eating habits. Dietary habits considered inappropriate included: consumption of fast food, sugary snacks, sugar-sweetened beverages and animal fats four or more times a week, and fruits, green vegetables, and leguminous vegetables less than four times a week. RESULTS: The prevalence of overweight among students was 24.6% (n = 145, high blood pressure, 11.1% (n = 65; passive smoking, 35.4% (n = 208; sedentary lifestyle, 52.3% (n = 306, family history of 1st degree disease: hypertension, 21.4%, obesity 36.5%. Food items eaten four or more times a week: fast food, 70.3% (n = 411; sugary snacks, 42.7% (n = 252, sugar-sweetened beverages, 71% (n = 419, and animal fats, 24.4% (n = 143. Food items eaten less than four times a week: fruits, 36.8% (n = 215, green vegetables, 49.5% (n = 292 and leguminous vegetables, 63.7% (n = 374. CONCLUSION: Interventions are needed to promote changes in students' eating habits: higher level of consumption of fruits, green vegetables and leguminous vegetables, and increased level of physical activity.

  15. Bentos litorâneo do Nordeste Oriental do Brasil: I. Povoamentos dos substratos móveis

    Directory of Open Access Journals (Sweden)

    Petrônio Alves Coelho

    1980-12-01

    Full Text Available The studied area is limited by São Francisco River mouth, to the South, and by Coroa das Lavadeiras, State of Rio Grande do Norte, to the North. This area presents only two seasons, summer and winter. During the summer, the freshwater inflow is smaller, the southeast winds are dominant, the temperature, the salinity and the transparence of water are high. The winter is characterized by greater freshwater inflow, east winds, smaller temperature and low salinity and transparence only in coastal and estuarine waters. Off São Francisco River mouth the water conditions are inverted and the salinity and transparence variations affect all continental shelf. In the soft bottoms are found the following communities: a Supralittoral beach; 2 Mediolittoral beach; 3 Infralittoral beach; 4 Circalittoral mud (São Francisco mouth; 5 Circalittoral gravel mud (São Francisco mouth.

  16. Genetic polymorphisms in catalase and CYP1B1 determine DNA adduct formation by bento(a)pyrene ex vivo

    NARCIS (Netherlands)

    Schults, Marten A.; Chiu, Roland K.; Nagle, Peter; Kleinjans, J C; van Schooten, Frederik Jan; Godschalk, Roger W.

    Genetic polymorphisms can partially explain the large inter-individual variation in DNA adduct levels following exposure to polycyclic aromatic hydrocarbons. Effects of genetic polymorphisms on DNA adduct formation are difficult to assess in human studies because exposure misclassification

  17. EFECTOS DE UN INUSUAL PERÍODO DE ALTA FRECUENCIA DE HURACANES SOBRE EL BENTOS DE ARRECIFES CORALINOS

    Directory of Open Access Journals (Sweden)

    Pedro M. Alcolado

    2011-07-01

    Full Text Available En arrecifes coralinos del suroeste de Cuba, se evaluaron los impactos de la inusitada frecuencia e intensidad de huracanes entre el 2001 y el 2007, y de las enfermedades de corales, ambos factores asociados al cambio climático. En las crestas arrecifales, la reducción de la cobertura de coral duro vivo varió de nula a 21%, mientras que la reducción del diámetro máximo promedio de los corales varió de 16 a 40 cm. En los arrecifes frontales, la reducción de la cobertura de coral varió de nula a 14%, mientras que la reducción del diámetro máximo promedio varió de nula a 26 cm. Sin embargo, en todos los sitios se observaron grandes cambios en el predominio numérico de las especies. En las crestas, este se desplazó de  Acropora palmata y otros corales duros hacia Millepora complanata, Porites astreoides o Acropora prolifera. En los arrecifes frontales, el cambio ocurrió de la dominancia de Montastraea annularis (complejo de especies, Diploria strigosa y Agaricia agaricites a la de P. astreoides o Siderastrea siderea. Con esos cambios, las crestas están perdiendo efectividad como refugios y como disipadoras del oleaje, a causa de la reducción de complejidad estructural. La densidad del erizo Diadema antillarum se mantuvo insignificante y sin cambio en el sur del Golfo de Batabanó, mientras que se incrementó de manera importante en la cresta de Faro Cazones. Los porcentajes de mortalidad reciente y de incidencia de enfermedades de corales se mantuvieron bajos, lo que sugiere una influencia dominante de los huracanes en la condición de los arrecifes coralinos evaluados. In coral reefs of southwestern Cuba, we assessed the impacts from unprecedented frequent and intense hurricanes during the period 2001-2007, and from coral diseases, which are both factors considered to be associated with climate change.. At the reef crests, live hard coral cover reduction varied from null to 21%, while maximum average coral diameter reduction varied from 16 to 40 cm. In the fore-reefs, the reduction of coral cover varied from null to 14%, while diameter reduction varied from null to 26 cm. However, at all sites, great shifts in species dominance patterns were observed. In reef crests, numerical dominance of Acropora palmata and other hard corals shifted towards increases of Millepora complanata or, to a lesser extent, of Porites astreoides or Acropora prolifera. At the fore-reefs, the shifts occurred from the dominance of Montastraea annularis complex, Diploria strigosa and Agaricia agaricites, towards combined increases of P. astreoides or Siderastrea siderea. With those ongoing changes, reef crests are losing effectiveness as refuges and wave dissipators because of reduction of structural complexity. The population density of the sea-urchin Diadema antillarum remained negligible and unchanged in the southern Gulf of Batabanó, while it increased significantly at the Faro Cazones reef crest. Percentages of recent mortality and percentages of disease incidence in corals remained low, suggesting a dominant influence from hurricanes on assessed coral reef decline.

  18. Poder civil y derechos naturales de los indios americanos según Fray Alonso de la Veracruz

    Directory of Open Access Journals (Sweden)

    Manuel Méndez Alonzo

    2013-01-01

    Full Text Available El presente trabajo investiga las tesis sobre el poder civil de Alonso de la Veracruz que buscan incorporar en la comunidad política española a los habitantes autóctonos del Nuevo Mundo, tesis que suelen relacionarse con F. de Vitoria y el tomismo español, y que últimamente son consideradas parte del republicanismo novohispano elaborado desde la periferia americana. Se busca demostrar que su propósito era aplicar una teoría de derechos naturales, sin que ello implique participación política de los indios americanos. Se analiza la postura del fraile frente a la diversidad cultural y la guerra contra los indios.

  19. Stone-age mass spectrometry: the beginnings of "SIMS" at RCA Laboratories, Princeton

    Science.gov (United States)

    Honig, Richard E.

    1995-05-01

    This paper takes you back almost half a century, to the time when mass spectrometry was young and exciting, and research was exploring new frontiers every day. Our early experiments called "sputtering of surfaces by positive ion beams", now known as "SIMS", were carried out with the simple, yet flexible instrumentation available at that time and produced many interesting results that are still valid today. Since commercial equipment did not exist in those days, just about everything had to be designed and constructed in-house - hardware as well as circuitry. Thus progress was slow, but occasional malfunctioning of a component could be readily rectified. It is gratifying to see how SIMS has developed in the interim from our early feasibility studies into a major research effort carried out worldwide in many laboratories.

  20. Country report for the regional (RCA) training workshop on contamination monitoring

    International Nuclear Information System (INIS)

    Shantha, T.H.S.

    1997-01-01

    The Atomic Energy Authority (AEA) is the organization in Sri Lanka responsible for the regulatory and development of applications in nuclear technology. AEA was established in 1969 by the AEA Act No. 19 of 1969 and at present it is under the Ministry of Science, Technology and Human Resources Development. As a developing country, Sri Lanka still needs technical assistance to support the development of application in nuclear technology. So far this country doesn't have any type of nuclear reactors. Most of activities in Sri Lanka are in health sector using x-ray and radioisotopes for diagnostic and therapeutic purposes. In addition to that few number of radioisotopes are used in industrial and research institutes. In this paper, the following items are described: radiation protection activities, emergency preparation and planning, food testing program, and nuclear technique in monitoring industrial pollution. (G.K.)

  1. Country report for the regional (RCA) training workshop on contamination monitoring

    Energy Technology Data Exchange (ETDEWEB)

    Shantha, T H.S. [Atomic Energy Authority (Sri Lanka)

    1997-06-01

    The Atomic Energy Authority (AEA) is the organization in Sri Lanka responsible for the regulatory and development of applications in nuclear technology. AEA was established in 1969 by the AEA Act No. 19 of 1969 and at present it is under the Ministry of Science, Technology and Human Resources Development. As a developing country, Sri Lanka still needs technical assistance to support the development of application in nuclear technology. So far this country doesn`t have any type of nuclear reactors. Most of activities in Sri Lanka are in health sector using x-ray and radioisotopes for diagnostic and therapeutic purposes. In addition to that few number of radioisotopes are used in industrial and research institutes. In this paper, the following items are described: radiation protection activities, emergency preparation and planning, food testing program, and nuclear technique in monitoring industrial pollution. (G.K.)

  2. Factors associated with stunting in healthy children aged 5 years and less living in Bangui (RCA.

    Directory of Open Access Journals (Sweden)

    Pascale Vonaesch

    Full Text Available Stunting remains a major public health concern worldwide. Although its global prevalence is slowly decreasing, the actual number of affected children is still rising in Sub-Saharan Africa. In the Central African Republic (CAR, about one third of all children below the age of five are stunted. Stunting is correlated with many long-term consequences, including poor cognitive development and a higher rate of morbidity and mortality, making stunting a major contributor to poverty. In CAR, little is known about the factors that contribute to stunting. This study aimed at analysing, in a cross-sectional study, the main factors associated with stunting in a group of 414 children recruited between December 2011 and November 2013, aged five years or less and living in Bangui. For all children, demographic, socio-economic and anthropometric data were recorded and asymptomatic enteropathogen carriage was assessed in stool samples using classical microbiological assays. The study group had a mean age of 14.2±10 months. Fifty-eight percent (292/414 were boys, and 36 percent (148/414 exhibited stunted growth. Of the stunted children, 51% (75/148 showed a moderate delay in linear growth for their age group [height-for-age z-score (HAZ between -2 and -3 SD] while 49% (73/148 presented a severe delay (HAZ 2 SD; aOR: 3.21; 95% CI: 1.50; 6.90 of overweight compared to normal weight] as also being significantly associated with stunting. This is the first study showing that even in the poorest countries of the world there is an association of stunting with being overweight.

  3. Factors associated with stunting in healthy children aged 5 years and less living in Bangui (RCA).

    Science.gov (United States)

    Vonaesch, Pascale; Tondeur, Laura; Breurec, Sébastien; Bata, Petula; Nguyen, Liem Binh Luong; Frank, Thierry; Farra, Alain; Rafaï, Clotaire; Giles-Vernick, Tamara; Gody, Jean Chrysostome; Gouandjika-Vasilache, Ionela; Sansonetti, Philippe; Vray, Muriel

    2017-01-01

    Stunting remains a major public health concern worldwide. Although its global prevalence is slowly decreasing, the actual number of affected children is still rising in Sub-Saharan Africa. In the Central African Republic (CAR), about one third of all children below the age of five are stunted. Stunting is correlated with many long-term consequences, including poor cognitive development and a higher rate of morbidity and mortality, making stunting a major contributor to poverty. In CAR, little is known about the factors that contribute to stunting. This study aimed at analysing, in a cross-sectional study, the main factors associated with stunting in a group of 414 children recruited between December 2011 and November 2013, aged five years or less and living in Bangui. For all children, demographic, socio-economic and anthropometric data were recorded and asymptomatic enteropathogen carriage was assessed in stool samples using classical microbiological assays. The study group had a mean age of 14.2±10 months. Fifty-eight percent (292/414) were boys, and 36 percent (148/414) exhibited stunted growth. Of the stunted children, 51% (75/148) showed a moderate delay in linear growth for their age group [height-for-age z-score (HAZ) between -2 and -3 SD] while 49% (73/148) presented a severe delay (HAZ 2 SD; aOR: 3.21; 95% CI: 1.50; 6.90 of overweight compared to normal weight] as also being significantly associated with stunting. This is the first study showing that even in the poorest countries of the world there is an association of stunting with being overweight.

  4. Ligation-based mutation detection and RCA in surface un-modified OSTE+ polymer microfluidic chambers

    DEFF Research Database (Denmark)

    Saharil, Farizah; Ahlford, Annika; Kuhnemund, Malte

    2013-01-01

    For the first time, we demonstrate DNA mutation detection in surface un-modified polymeric microfluidic chambers without suffering from bubble trapping or bubble formation. Microfluidic devices were manufactured in off-stoichiometry thiol-ene epoxy (OSTE+) polymer using an uncomplicated and rapid...... during bio-operation at elevated temperatures. In contrast, PMMA, PDMS and COP microfluidic devices required specific surface treatment....

  5. IAEA-RCA training course on in-service inspection of research reactors

    International Nuclear Information System (INIS)

    2002-01-01

    Bhabha Atomic Research Centre (BARC) has acquired a wide range of experience for over four decades in design, construction, operation and maintenance of research reactors. The two-week training course on In-Service Inspection of Research Reactors (ISI) has greatly increased the awareness in the field of ISI of Research Reactors. The training course has been formulated so as to cover most of the topics relevant to ISI of research reactors. Important topics such as rationale for in-service inspection, material degradation mechanisms, non-destructive examination techniques, design evaluation of flaws and radiological, codal and regulatory aspects of ISI for research reactors were covered. Lectures on ISI of elastomeric materials and concrete structures, which are generally used in the construction of reactors have also been included in the course. Papers relevant to INIS are indexed separately

  6. Línea de base para evaluar el impacto de una planta de celulosa en el Río Uruguay

    Directory of Open Access Journals (Sweden)

    Carlos Saizar

    2011-05-01

    Full Text Available Como parte del proceso de evaluación del impacto ambiental ante la puesta en funcionamiento de la planta de pulpa de celulosa Kraft Botnia (actual UPM, se realizaron estudios de línea de base entre los años 2005 y 2007. El diseño de muestreo incluyó tres transectas perpendiculares a la línea de costa, en tres sitios: Nuevo Berlín, Fray Bentos y Las Cañas. Se realizaron estudios de parámetros físico-químicos del agua (nutrientes, sustancias orgánicas, metales, compuestos orgánicos adsorbibles (AOX, dioxinas y furanos, materia orgánica y granulometría del sedimento, estudios biológicos de las comunidades planctónicas, zoobentónicas e ícticas y bioacumulación de dioxinas en peces. El fósforo en la columna de agua presentó en promedio valores por encima de lo recomendado por la normativa nacional, mientras los contaminantes orgánicos (AOX, clorofenoles, ácidos resínicos, fitosteroles, dioxinas y furanos se mantuvieron por debajo de los valores guía recomendados a nivel internacional. Las comunidades planctónicas variaron significativamente entre muestreos, la de peces entre sitios y muestreos, mientras que la de bentos no presentó variaciones significativas espaciales ni temporales. El bagre trompudo (Iheringichthys labrosus es propuesto como especie a sermonitoreada debido a su ubicuidad y abundancia. Este trabajo ofrece una visión general de los estudios de línea de base, destacando la multiplicidad y la periodicidad de los parámetros en dos años de estudio.

  7. Dietary habits and risk factors for atherosclerosis in students from Bento Gonçalves (state of Rio Grande do Sul).

    Science.gov (United States)

    Cimadon, Hosana Maria Speranza; Geremia, Renata; Pellanda, Lucia Campos

    2010-08-01

    Atherosclerotic cardiovascular disease begins its process in early childhood and is influenced throughout life by genetic factors and environmental exposure to potentially modifiable risk factors. To investigate the prevalence of risk factors for atherosclerosis with emphasis on dietary habits in a predominantly Italian colonization town. Population-based cross sectional study, involving 590 primary school students aged between 9 and 18 years, with a cluster sample. The following were collected: identification data, family history and personal history, and information regarding students' eating habits. Dietary habits considered inappropriate included: consumption of fast food, sugary snacks, sugar-sweetened beverages and animal fats four or more times a week, and fruits, green vegetables, and leguminous vegetables less than four times a week. The prevalence of overweight among students was 24.6% (n = 145), high blood pressure, 11.1% (n = 65); passive smoking, 35.4% (n = 208); sedentary lifestyle, 52.3% (n = 306), family history of 1st degree disease: hypertension, 21.4%, obesity 36.5%. Food items eaten four or more times a week: fast food, 70.3% (n = 411); sugary snacks, 42.7% (n = 252), sugar-sweetened beverages, 71% (n = 419), and animal fats, 24.4% (n = 143). Food items eaten less than four times a week: fruits, 36.8% (n = 215), green vegetables, 49.5% (n = 292) and leguminous vegetables, 63.7% (n = 374). Interventions are needed to promote changes in students' eating habits: higher level of consumption of fruits, green vegetables and leguminous vegetables, and increased level of physical activity.

  8. General characteristics of the aquifer system Joanicó (Montevideo, Uruguay)

    International Nuclear Information System (INIS)

    Gagliardi Urtasun, S.; Montaño, X.; Montaño Gutiérrez, M.; Lacués Parodi, X.

    2010-01-01

    The work area, comprising the towns of Joanicó, Sauce and N Progress , Canelones province, is a center of intensive agricultural development (viticulture, hortofruticultura, etc), where demand and exploitation of groundwater is common primarily for irrigation supply .The subsoil consists of sedimentary rocks and sediments belonging to the Freedom and Dolores ( Pleistocene), Fray Bentos (Upper Oligocene) (aquitards), Mercedes formations - Asencio (Upper Cretaceous) and Migues (Lower Cretaceous). Permeable levels in the Mercedes and Migues formations make up a significant potential aquifer system , which we call Joanicó Aquifer System. This aquifer is multilayer type and consists of fine to coarse sand and gravel and sand mixture , with the occasional presence of thin matrix. Semi confined and behaves as confined in most area; in the outcrop of the Merc edes training is free. The average transmissivity is approximately the 50m2/día; The average permeability of 5 to 10 m/day. The storage coefficient (confined area) is of the order 10-4 .In the most developed area of the aquifer is where Joanicó are obtained by constructing boreholes higher flows Canelones department: more than 25% of the wells drilled to extract higher flow 15 m3/h y extracted more than 40% flows over 10 m3/h. The production of many agricultural enterprises depends directly on the area irrigated with groundwater, so the deeper knowledge of the exploited resource is paramount

  9. Media framing of techno-environmental controversies: A case study of the 'Paper-Mills Conflict’ between Argentina and Uruguay

    Directory of Open Access Journals (Sweden)

    Carina Cortassa

    2014-06-01

    Full Text Available This article embraces the framing studies’ perspective to approach the media construction of the current techno-environmental controversy between Argentina and Uruguay, due to the location of an industrial plant to produce cellulose paper in the uruguayan community of Fray Bentos. The analysis is centered on the respective coverages developed by two argentinean print media –daily newspapers Clarín and Página 12– during three key stages in the evolution of the conflict. A sample composed of 1004 articles was examined using a protocol based in previously tested instruments, which was elaborated to quantify the incidence of five frames established a priori: a environmental; b scientific-technological; c political-juridical; d social; e of economic causes & consequences. The evidence collected indicates that the analyzed media represented the controversy mostly in political-juridical terms and drastically overshadowed its environmental origins and the discrepancies of scientific and technical nature involved in its roots and development. The article discusses some results of the research experience, as well as the limitations and posibilites to extend the framing typology rehearsed here to other media coverages of similar situations, independently of its specific object.

  10. Evaluación de la remoción de nutrientes y compuestos organoclorados y sus rutas de bioacumulación con la planta flotante Eichhornia crassipes expuesta a efluentes de pulpa de celulosa

    Directory of Open Access Journals (Sweden)

    Diana Margarita Míguez Caramés

    2014-12-01

    Full Text Available El presente trabajo piloto tuvo como objetivo estudiar el proceso de bioacumulación de nutrientes y compuestos organoclorados en Eichhornia crassipes expuesta a efluentes de una fábrica de celulosa que vierte en aguas del Río Uruguay, cerca de la ciudad de Fray Bentos, Río Negro, Uruguay. Se caracterizaron los principales atributos del efluente, antes y después del cultivo con Eichhornia, así como también se estudiaron las concentraciones de los halógenos orgánicos en plantas control y en plantas sometidas al efluente. Se observaron cambios macroscópicos en la planta, los compuestos organoclorados se bioacumularon principalmente en las hojas, registrándose valores de 9,4 µg/g frente a 2,1 µg/g observados en la biomasa control. La remoción de nutrientes fue del orden del 90%. Los resultados obtenidos sugieren que la fitorremediación con plantas flotables es un método potencialmente ventajoso para ser utilizado como tratamiento terciario en países tropicales y subtropicales para disminuir la concentración de compuestos orgánicos clorados recalcitrantes y como método de remoción de nitratos y fosfatos de efluentes de plantas de celulosa.

  11. Carta del Duque de Alcoy al Padre Pedro Abarca sobre un asunto concerniente al Padre Rector Fray Francisco Díaz

    OpenAIRE

    2012-01-01

    "Señor mio. Reciuo la carta de V[uestra] R[everendisi]ma con el gusto que [...]" Manuscrito. -- 1 h. [P.V. 3 - f. 92-92v.] [ff. 93-94v. en blanco] : Papel; 205x300mm. -- Buena conservación. Texto en Castellano. -- Firma autógrafa; letra bastarda. Vivas Moreno, Agustín. "Fondos documentales del Archivo Histórico de la Universidad de Salamanca. La colección de Papeles Varios: análisis descriptivo, tesauro y gestión documental automatizada". Tesis doctoral, 1999. Las descripciones fuero...

  12. Dos composiciones a la Virgen: Fray Luis de León y Francesco Petrarca (Una muestra de sorprendente analogía

    Directory of Open Access Journals (Sweden)

    Rossana Soriani

    2016-04-01

    Full Text Available El estudio pretende realizar una comparación entre dos poemas dedicados a la Virgen María, y se propone establecer los méritos propios y las cualidades del canto mariano creado por el poeta salmantino que imita, cómo era habitual en el renacimiento, al poeta de su admiración, Francesco Petrarca.   This study presents a comparation between two poems dedicated to de Virgen Mary, and establishes the merits and qualities of the Marian canto created by the Salamancan poet, as was common in the Renaissance, the poet he admired, Francesco Petarch.

  13. La construcción de una identidad literaria en la corte de Carlos V: el caso de Fray Antonio de Guevara

    Directory of Open Access Journals (Sweden)

    Emilio Blanco

    2012-06-01

    Full Text Available El primer conjunto de la producción guevariana, lo que se ha llamado el Ciclo de los Emperadores Romanos, presenta unas particularidades especiales, al haber sido el responsable de la fama inicial de Guevara, tanto en el ámbito cortesano como en toda Europa. Hay motivos internos que explican el éxito de estas obras, pero un análisis detallado de textos y paratextos demuestra que obedecen igualmente a una estrategia cortesana urdida por el franciscano para imponer en la Corte su concepto de literatura frente a otros tipos de diversión áulica (libros de ficción, truhanes y juglares o frente a colectivos con influencia que apartan al autor de la consideración privativa de Carlos V, como los médicos.Le premier ensemble de la production d’Antonio de Guevara, qu’on a appelé le Cycle des empereurs romains, présente certaines particularités du fait d’avoir été à l’origine de la première réputation de Guevara, tant dans le milieu de la cour que dans l’Europe tout entière. Des motifs internes à ces œuvres peuvent en expliquer le succès, mais une analyse attentive des textes et des paratextes démontre qu’ils obéissent également à une stratégie courtisane ourdie par le franciscain pour imposer dans la cour sa conception de la littérature, opposée à celle d’autres types de divertissement aulique (livres de fiction, bouffons et jongleurs ou à l’influence de groupes qui écartent l’auteur de la proximité privée de Charles-Quint, tels les médecins.

  14. Et certe opera Deus facit mediantibus causis secundis”: fray Luis de León y la determinación del derecho

    Directory of Open Access Journals (Sweden)

    Sebastián Contreras Aguirre

    2014-06-01

    Full Text Available Luis de León is one of the most important figures of so called Scholastic of Salamanca. In his work, that is the culmination of the Augustinian school of the sixteenth century, are present the most different activities (jurist, prose writer, theologian, poet, etc. and the most different schools of thought (Thomism, Nominalism, Humanism, etc.. The legal philosophy of León, which is what interests us now, has been apparently overshadowed by his reputation as a writer and mystic. But this does not make his work as jurist in not valuable. On the contrary, the legal ideas of Spanish thinker represent one of principal pieces of Theological School of Salamanca

  15. Eclecticism and Rhetoric in the Brazilian philosophy: from Silvestre Pinheiro Ferreira (1769-1846) to Fray Francisco do Monte Alverne (1784-1858)

    OpenAIRE

    Duran, Maria Renata da Cruz; Universidade Estadual de Londrina

    2015-01-01

    Este artigo trata da filosofia eclética de Victor Cousin conforme seus repetidores brasileiros do início do século XIX: Silvestre Pinheiro Pereira e frei Francisco do Monte Alverne. O objetivo principal é estudar as relações entre o ecletismo e a retórica em prol da justificação dos limites, da dispersão e da superficialidade do debate filosófico local. Revisando as obras de Antônio Paim, Laerte Ramos de Carvalho e Maria Beatriz Nizza da Silva, destacou-se, especialmente, alguns pressupostos ...

  16. EFECTOS DE LA FRAGMENTACION SOBRE LA DISTRIBUCION DE ESPECIES ARBOREAS EN EL PARQUE NACIONAL FRAY JORGE: IMPORTANCIA DE LOS ATRIBUTOS ECOFISIOLOGICOS

    OpenAIRE

    SALGADO NEGRET, BEATRIZ EUGENIA

    2013-01-01

    El estudio de los rasgos funcionales y mecanismos fisiológicos que determinan la tolerancia de las especies a la sequía y su habilidad para competir por agua es fundamental para entender su distribución a través de gradientes de humedad y predecir su respuesta al cambio global, donde la fragmentación del hábitat y el cambio de uso del suelo son los principales motores de cambio. En este sentido, los bosques dependientes de neblina en las regiones semiáridas del mundo son un buen modelo de ...

  17. Public Key Infrastructure (PKI) Increment 2 Root Cause Analysis (RCA) for Performance Assessments and Root Cause Analyses (PARCA)

    Science.gov (United States)

    2015-05-01

    DoD PKI enables secure encryption , authentication of network transactions, data integrity, and non-repudiation to a broad range of government- and...Identity Verification (PIV) Authentication Certificates.  Implement Rivest, Shamir, and Adelman ( RSA ) 2048 when viable and transition to Secure Hash...facilitate missions through digital signing, encryption , and web-server authentication. However, reliability of the tokens was unacceptable, with

  18. Simulation of climate characteristics and extremes of the Volta Basin using CCLM and RCA regional climate models

    Science.gov (United States)

    Darko, Deborah; Adjei, Kwaku A.; Appiah-Adjei, Emmanuel K.; Odai, Samuel N.; Obuobie, Emmanuel; Asmah, Ruby

    2018-06-01

    The extent to which statistical bias-adjusted outputs of two regional climate models alter the projected change signals for the mean (and extreme) rainfall and temperature over the Volta Basin is evaluated. The outputs from two regional climate models in the Coordinated Regional Climate Downscaling Experiment for Africa (CORDEX-Africa) are bias adjusted using the quantile mapping technique. Annual maxima rainfall and temperature with their 10- and 20-year return values for the present (1981-2010) and future (2051-2080) climates are estimated using extreme value analyses. Moderate extremes are evaluated using extreme indices (viz. percentile-based, duration-based, and intensity-based). Bias adjustment of the original (bias-unadjusted) models improves the reproduction of mean rainfall and temperature for the present climate. However, the bias-adjusted models poorly reproduce the 10- and 20-year return values for rainfall and maximum temperature whereas the extreme indices are reproduced satisfactorily for the present climate. Consequently, projected changes in rainfall and temperature extremes were weak. The bias adjustment results in the reduction of the change signals for the mean rainfall while the mean temperature signals are rather magnified. The projected changes for the original mean climate and extremes are not conserved after bias adjustment with the exception of duration-based extreme indices.

  19. IAEA-RCA co-ordinated research programme compilation of anatomical, physiological and metabolic characteristics for a reference asian man

    International Nuclear Information System (INIS)

    Kawamura, H.; Tanaka, G.; Miah, F.K.

    1996-01-01

    The world-wide radiation protection concerns that followed the Chernobyl accident created an increased need for basic data to assess internal doses to members of the public in each country. Therefore, the Reference Asian Man Programme was proposed by Japan and initiated as a part of the IAEA Regional Cooperative Agreement Project for Strengthening Radiation Protection Infrastructure to coincide with the revision of Reference Man data by ICRP Committee 2. The first priority was given to compilation of data on physique, and mass of internal organs where possible, for populations throughout the Asian region. Data on daily consumption of foods and nutrients were also emphasized since they are important components of the ingestion pathway for uptake of radionuclides by humans. Pulmonary function and water balance parameters were considered important in relation to the inhalation pathway and water contamination. The programme was also endorsed by ICRP. (author)

  20. Andrzej Karpowicz – twórca Pracowni Zbiorów Masońskich Biblioteki Uniwersyteckiej w Poznaniu

    Directory of Open Access Journals (Sweden)

    Tomasz Kurzawa

    2011-01-01

    Full Text Available Artykuł omawia działalność naukową i zasługi w zakresie pracy bibliotecznej twórcy Pracowni Zbiorów Masońskich Biblioteki Uniwersyteckiej – mgra Andrzeja Karpowicza. Portret Andrzeja Karpowicza przedstawiony został na szerokim tle piśmiennictwa i źródeł do dziejów wolnomularstwa oraz sylwetek autorów zajmujących się wskazaną problematyką.

  1. The extent of myocardium at Risk for LAD, RCA and LCx using contrast enhanced SSFP and T2-weighted imaging

    DEFF Research Database (Denmark)

    Nordlund, D.; Heiberg, E.; Carlsson, Marcus

    2015-01-01

    in patients after STelevation myocardial infarction. Methods: CE-SSFP and T2w data from the recently published international multi-center trials CHILL-MI and MITOCARE, was used to assess MaR. CESSFP images from 206/212 patients (6 excluded due to inability to detect MaR) and T2w images from 147/212 patients...

  2. A INOVAÇÃO TECNOLÓGICA EM ARRANJOS PRODUTIVOS LOCAIS: A INDÚSTRIA DE MÓVEIS RETILÍNEOS RESIDENCIAIS DE BENTO GONÇALVES (RS)

    OpenAIRE

    Claudia Maria Sonaglio

    2006-01-01

    As rápidas mudanças dos últimos 20 anos, com destaque a ascensão das tecnologias de informação e comunicação, transformaram radicalmente os produtos, processos, formas de uso e a vida das pessoas. Isto aliado à liberalização comercial e financeira promoveu uma nova conformação empresarial. Entende-se que as inovações, em especial as tecnológicas, são motores da competição e do desenvolvimento industrial. Isso exige das empresas uma grande flexibilidade de produção, para que estas sejam cap...

  3. Estudo das populações de mariposas perfuradoras de frutos (Lepidoptera: Noctuidae) em parreirais dos municípios de Bento Gonçalves e Farroupilha, Rio Grande do Sul

    OpenAIRE

    Zenker, Maurício Moraes

    2009-01-01

    A morfologia da espirotromba de noctuídeos adultos pode indicar diferentes hábitos alimentares. Algumas espécies, conhecidas como mariposas perfuradoras de frutos, apresentam espirotromba adaptada para perfurar a casca (primárias) ou somente a polpa (secundárias) de frutos para se alimentar, causando danos em pomares, enquanto que em outras esse órgão é utilizado para obter néctar e/ou qualquer tipo de matéria orgânica disponível em estado líquido. Visando determinar, através da morfologia da...

  4. Benthic survey of natural and artificial reefs off Mar del Plata, Argentina, southwestern Atlantic Estudios del bentos de arrecifes naturales y artificiales de Mar del Plata, Argentina, Atlántico sudoccidental

    Directory of Open Access Journals (Sweden)

    Gabriel Genzano

    2011-11-01

    Full Text Available This study describes the macrofaunal assemblages of subtidal rocky reefs off Mar del Plata in order to compare the macro invertebrate assemblages settled on shipwrecks with those of nearby reef sand to characterize the fish fauna associated with natural (NR and artificial (AR reefs. Topographic characterizations and surveys of invertebrates and fishes were performed in November and December 2005, using SCUBA diving. A non-parametric multivariate analysis was used to analyze the environmental and biological data. The reefs were mainly distinguished by their depth and the position of the substrate. The red calcareous algae, Corallina officinalis, dominated the shallowest NR, whereas conspicuous mytilid assemblages of Mytilus platensis were present at depths over 3 m, sea anemones, Anthothoe chilensis, were more abundant between 6 and 10 m, and the soft coral, Tripalea clavaria, was found at nearly 20 m depth. No differences were found between horizontal ARs and the adjacent NRs. The greatest differences were found between the communities of vertical and horizontal substrates, both in NRs and ARs. Fifteen fish species were recorded in the analyzed area. Species having strong site fidelity, e.g., Acanthistius brasilianus and Pseudopercis semifasciata, were clearly more abundant and/or frequent in ARs (shipwrecks than in NRs. This pioneer study in the surveyed area showed that reef sallow the settlement of diverse benthic assemblages. ARs also provide refuge for fishes. As sport fishing and diving are activities being carried out in Mar del Plata, where tourism is one of the main economic resources, the protection of such areas should be considered in conservation plans.Se describió la macrofauna de los arrecifes rocosos sublitorales, frente a Mar del Plata, para comparar las asociaciones de macro-invertebrados de los pecios con las de los arrecifes aledaños y caracterizar la fauna de peces tanto en los arrecifes naturales (NR como artificiales (AR. Las caracterizaciones topográficas y los censos de invertebrados y peces se realizaron mediante buceo autónomo en noviembre y diciembre de 2005. Los datos ambientales y biológicos fueron analizados mediante análisis multivariados no paramétricos. Los arrecifes fueron principalmente discriminados acorde a su profundidad y posición del sustrato. El alga roja calcárea Corallina officinalis fue dominante en los NR poco profundos, mientras que conspicuas asociaciones del mitílido Mytilus platensis se encontraron a más de 3 m de profundidad; la anémona de mar Anthothoe chilensis fue más abundante a los 6-10 m y el coral blando Tripalea clavaria cerca de los 20 m de profundidad. No se evidenciaron diferencias entre los ARs de disposición horizontal y los NR aledaños. Las mayores diferencias fueron halladas en las comunidades de los sustratos verticales vs horizontales tanto en NRs y ARs. Se registraron 15 especies de peces. Aquellas con fuerte fidelidad por el habitat, e.g. Acanthistius brasilianus y Pseudopercis semifasciata, fueron claramente más abundantes y/o frecuentes en los ARs (pecios en comparación con los NRs. Este estudio pionero en el área mostró que los arrecifes permiten la fijación de diversas asociaciones bentónicas. Los ARs aportan además refugio para los peces. Debido a que la pesca recreacional y el buceo son actividades que se están desarrollando en Mar del Plata, donde el turismo es uno de los principales recursos económicos, la protección de estas áreas debería considerarse en los planes de conservación.

  5. Co-ordinated research project on isotopic evaluations in infant growth monitoring - a collaboration with WHO (partly RCA). Report on the first research co-ordination meeting

    International Nuclear Information System (INIS)

    2000-01-01

    This Coordinated Research Project (CRP) came about as an initiative to collaborate with the WHO Multicenter Growth Reference Study (MGRS) to generate new growth reference data for breastfed babies using stable isotopes. The WHO MRGS measures growth using anthropometric measurements (e.g. height and weight) in healthy infants and young children in different countries and continents. All participants are fed according to strict criteria regarding duration and frequency of breast-feeding. The MGRS' main goal is to develop a truly international growth standard to look at growth pattern of healthy breast-fed babies. Nevertheless, the composition of the growth (fat/lean tissue) and the nutrient intake that produced the standard growth were not originally included in the study. In order to address these and other important issues related to the baby's body composition and growth, a fruitful collaboration between the WHO and the IAEA has been established. The Agency technical experts and consultants will assist developing countries to carry out isotopic work to measure infant's growth using the in vivo kinetics technique. The objective of this CRP is to measure breast milk intake, using stable isotopes in a subgroup of breast-fed infants growing normally, and to assess their nutrient intakes. Furthermore, the results from the participating projects will provide new and valuable information on the nutrient requirement of healthy breast-fed babies, who were fed according to the WHO standard protocols

  6. Capability of the SMHI-RCA4 RCM driven by the ERA-Interim reanalysis to simulate heat waves in Argentina

    Czech Academy of Sciences Publication Activity Database

    Collazo, S.; Lhotka, Ondřej; Rusticucci, M.; Kyselý, Jan

    2018-01-01

    Roč. 38, č. 1 (2018), s. 483-496 ISSN 0899-8418 R&D Projects: GA MŠk 7AMB15AR001; GA ČR(CZ) GA16-22000S Institutional support: RVO:68378289 Keywords : Argentina * ENSO * extreme events * heat waves * maximum temperature * RCM Subject RIV: DG - Athmosphere Sciences, Meteorology OBOR OECD: Meteorology and atmospheric sciences Impact factor: 3.760, year: 2016 http://onlinelibrary.wiley.com/doi/10.1002/joc.5190/full

  7. An Analysis of the RCA Price-S Cost Estimation Model as it Relates to Current Air Force Computer Software Acquisition and Management.

    Science.gov (United States)

    1979-12-01

    because of the use of complex computational algorithms (Ref 25). Another important factor effecting the cost of soft- ware is the size of the development...involved the alignment and navigational algorithm portions of the software. The second avionics system application was the development of an inertial...001 1 COAT CONL CREA CINT CMAT CSTR COPR CAPP New Code .001 .001 .001 .001 1001 ,OO .00 Device TDAT T03NL TREA TINT Types o * Quantity OGAT OONL OREA

  8. The influence of kind of coating additive on the compressive strength of RCA-based concrete prepared by triple-mixing method

    Science.gov (United States)

    Urban, K.; Sicakova, A.

    2017-10-01

    The paper deals with the use of alternative powder additives (fly ash and fine fraction of recycled concrete) to improve the recycled concrete aggregate and this occurs directly in the concrete mixing process. Specific mixing process (triple mixing method) is applied as it is favourable for this goal. Results of compressive strength after 2 and 28 days of hardening are given. Generally, using powder additives for coating the coarse recycled concrete aggregate in the first stage of triple mixing resulted in decrease of compressive strength, comparing the cement. There is no very important difference between samples based on recycled concrete aggregate and those based on natural aggregate as far as the cement is used for coating. When using both the fly ash and recycled concrete powder, the kind of aggregate causes more significant differences in compressive strength, with the values of those based on the recycled concrete aggregate being worse.

  9. The bZIP Transcription Factor Rca1p Is a Central Regulator of a Novel CO2 Sensing Pathway in Yeast

    Czech Academy of Sciences Publication Activity Database

    Cottier, F.; Raymond, M.; Kurzai, O.; Bolstad, M.; Leewattanapasuk, W.; Jiménez-López, M.; Lorenz, M. C.; Sanglard, D.; Váchová, Libuše; Pavelka, N.; Palková, Z.; Mühlschlegel, F. A.

    2012-01-01

    Roč. 8, č. 1 (2012), e1002485 ISSN 1553-7366 R&D Projects: GA MŠk(CZ) LC531 Institutional research plan: CEZ:AV0Z50200510 Keywords : CARBONIC-ANHYDRASE CAN2 * CANDIDA -ALBICANS * SACCHAROMYCES-CEREVISIAE Subject RIV: EE - Microbiology, Virology Impact factor: 9.127, year: 2011

  10. Capability of the SMHI-RCA4 RCM driven by the ERA-Interim reanalysis to simulate heat waves in Argentina

    Czech Academy of Sciences Publication Activity Database

    Collazo, S.; Lhotka, Ondřej; Rusticucci, M.; Kyselý, J.

    2017-01-01

    Roč. 38, č. 1 (2017), s. 483-496 ISSN 0899-8418 Institutional support: RVO:67179843 Keywords : heat waves * RCM * maximum temperature * ENSO * Argentina * extreme events Subject RIV: DG - Athmosphere Sciences, Meteorology OBOR OECD: Environmental sciences (social aspects to be 5.7) Impact factor: 3.760, year: 2016

  11. Co-ordinated research project on isotopic evaluations in infant growth monitoring - a collaboration with WHO (partly RCA). Report on the first research co-ordination meeting

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-07-01

    This Coordinated Research Project (CRP) came about as an initiative to collaborate with the WHO Multicenter Growth Reference Study (MGRS) to generate new growth reference data for breastfed babies using stable isotopes. The WHO MRGS measures growth using anthropometric measurements (e.g. height and weight) in healthy infants and young children in different countries and continents. All participants are fed according to strict criteria regarding duration and frequency of breast-feeding. The MGRS' main goal is to develop a truly international growth standard to look at growth pattern of healthy breast-fed babies. Nevertheless, the composition of the growth (fat/lean tissue) and the nutrient intake that produced the standard growth were not originally included in the study. In order to address these and other important issues related to the baby's body composition and growth, a fruitful collaboration between the WHO and the IAEA has been established. The Agency technical experts and consultants will assist developing countries to carry out isotopic work to measure infant's growth using the in vivo kinetics technique. The objective of this CRP is to measure breast milk intake, using stable isotopes in a subgroup of breast-fed infants growing normally, and to assess their nutrient intakes. Furthermore, the results from the participating projects will provide new and valuable information on the nutrient requirement of healthy breast-fed babies, who were fed according to the WHO standard protocols.

  12. Final report for the IAEA urban aquifers RCA : determining the effects of storm water infiltration on groundwater quality in an urban fractured rock aquifer, Auckland, New Zealand

    International Nuclear Information System (INIS)

    Rosen, M.R.; Hong, Y.S.; Sheppard, D.; Roberts, K.; Viljevac, Z.; Smaill, A.; Reeves, R.R.

    2000-01-01

    Disposal of storm water in the Mt Eden-Mt Albert area of Auckland, New Zealand, is via ''soak holes'' drilled directly into the top of the fractured basalt. These soak holes receive storm water and sediment runoff from city streets throughout Mt Eden. Although this method of disposal has been used for at least 60 years, its sustainability with respect to groundwater quality has not been addressed. This study aimed to determine the impact of soakage on the chemical and isotopic composition of the groundwater. In addition, sediments captured by the soak holes were analysed to determine their effectiveness at trapping contaminants. Groundwater samples were collected between August 1998 and August 1999. Three sampling trips were carried out after rainfall events in October 1998, April 1999 and August 1999. Samples were analysed for major and trace components, including nutrients, dissolved and total heavy metals (As, Cr, Cu, Zn, Pb, Cd, and Ni), polynuclear aromatic hydrocarbons (PAHs), chlorofluorocarbons (CFCs) and stable and radiogenic isotopes. Cores of sediment collected in the soak holes were analysed for major components, total and leachable heavy metals, and PAHs to determine the ability of the sediments to adsorp contaminants. In summary, the Mt Eden aquifer system shows the effect of storm water infiltration rapidly after a rainfall event in some parts of the aquifer. Water quality has been effected in some areas, but in general the water quality is quite good considering the quantity of storm water discharge that has occurred in the area for the past 60 years. The relatively high quality of the water in the wells monitored may be attributed to the ability of the accumulated sediment in the soak holes and the aquifer fractures to trap contaminants. Further research is needed to determine if continued use of the groundwater system as a conduit for storm water infiltration will lead to clogging of the fractures in the aquifer and/or transport of particulates and colloids into the aquifer and a gradual deterioration in groundwater quality. (author). 41 refs., 16 figs., 14 tabs

  13. Long-term research in Bosque Fray Jorge National Park: Twenty years studying the role of biotic and abiotic factors in a Chilean semiarid scrubland Investigación de largo plazo en el Parque Nacional Bosque Fray Jorge: Veinte años estudiando el rol de los factores bióticos y abióticos en un matorral chileno semiárido

    Directory of Open Access Journals (Sweden)

    JULIO R GUTIÉRREZ

    2010-03-01

    Full Text Available Since 1989, we have conducted a large-scale ecological experiment in semiarid thorn scrub of a national park in north-central Chile. Initially, we focused on the role of biotic interactions including predation, interspecific competition, and herbivory in small mammal and plant components of the community. We utilized a reductionist approach with replicated 0.56 ha fenced grids that selectively excluded vertebrate predators and/or larger small mammal herbivores such as the degu, Octodon degus. Although we detected small transitory effects of predator exclusions on degu survival and numbers, other species failed to show responses. Similarly, interspecific competition (i.e., degus with other small mammals had no detectable numerical effects (although some behavioral responses occurred, and degu-exclusions had relatively small effects on various plant components. Modeling approaches indicate that abiotic factors play a determining role in the dynamics of principal small mammal species such as O. degus and the leaf-eared mouse (Phyllotis darwini. In turn, these are mainly related to aperiodic pulses of higher rainfall (usually during El Niño events which trigger ephemeral plant growth; a food addition experiment in 1997-2000 verified the importance of precipitation as a determinant of food availability. Since 2004, we have expanded long-term monitoring efforts to other important community components including birds and insects in order to understand effects of abiotic factors on them; we report some of the first results of comprehensive surveys on the former in this region. Finally, we recently shifted focus to documenting effects of exotic lagomorphs in the park. We installed additional treatments selectively excluding small mammals, lagomorphs, or both, from replicated grids in order to evaluate putative herbivore impacts. In conjunction with increased annual rainfall since 2000, we predict that introduced lagomorphs will have increasing impacts in this region, and that more frequent El Niños in conjunction with global climatic change may lead to marked changes in community dynamics. The importance of long-term experimental studies is underscored by the fact that only now after 20 years of work are some patterns becoming evident.Desde 1989 hemos llevado a cabo un experimento ecológico a gran escala en un matorral espinoso semiárido de un parque nacional en el norte de Chile. Inicialmente, nos centramos en el rol de las interacciones bióticas incluyendo depredación, competencia interespecífica y herbivoría en micromamíferos y componentes vegetales de la comunidad. Usamos una aproximación reduccionista con parcelas replicadas cercadas de 0.56 ha que selectivamente excluían depredadores vertebrados y/o micromamíferos herbívoros más grandes como el degu, Octodon degus. Aunque detectamos efectos transitorios menores en la sobrevivencia y número de degus en las exclusiones de depredadores, otras especies no mostraron respuestas. Similarmente, la competencia interespecífica (i.e., degus con otros micromamíferos no tenía efectos numéricos detectables (aunque ocurrieron algunas respuestas conductuales, y las exclusiones tuvieron efectos relativamente pequeños en varios componentes vegetales. Aproximaciones basadas en modelos indican que los factores abióticos juegan un papel determinante en la dinámica de las especies de micromamíferos principales como O. degus y la laucha orejuda (Phyllotis darwini. En cambio, estos están principalmente relacionados a pulsos no periódicos de lluvias más altas (usualmente durante los eventos El Niño que gatilla el crecimiento de plantas efímeras; un experimento de adición de alimento en 1997-2000 verificó la importancia de la precipitación como un determinante de la disponibilidad de alimento. Desde el 2004 hemos expandido los esfuerzos de monitoreo de largo plazo a otros componentes comunitarios importantes incluyendo aves e insectos con el fin de entender los efectos de los factores abióticos sobre ellos; informamos algunos de los primeros resultados de censos comprehensivos de aves en esta región. Finalmente, hace poco cambiamos de foco para documentar el efecto de lagomorfos exóticos en el parque. Instalamos tratamientos adicionales excluyendo selectivamente micromamíferos, lagomorfos, o ambos, de parcelas replicadas con el fin de evaluar impactos de herbívoros. En conjunto con el aumento de la precipitación anual desde 2000, predecimos que los lagomorfos introducidos tendrán mayores impactos en esta región y que más frecuentes El Niño en combinación con el cambio climático global puede conducir a cambios marcados en la dinámica comunitaria. La importancia de experimentos de largo plazo es destacado por el hecho que solamente ahora después de 20 años de trabajo algunos patrones están siendo evidentes.

  14. Purification and sequencing of radish seed calmodulin antagonists phosphorylated by calcium-dependent protein kinase.

    Science.gov (United States)

    Polya, G M; Chandra, S; Condron, R

    1993-02-01

    A family of radish (Raphanus sativus) calmodulin antagonists (RCAs) was purified from seeds by extraction, centrifugation, batch-wise elution from carboxymethyl-cellulose, and high performance liquid chromatography (HPLC) on an SP5PW cation-exchange column. This RCA fraction was further resolved into three calmodulin antagonist polypeptides (RCA1, RCA2, and RCA3) by denaturation in the presence of guanidinium HCl and mercaptoethanol and subsequent reverse-phase HPLC on a C8 column eluted with an acetonitrile gradient in the presence of 0.1% trifluoroacetic acid. The RCA preparation, RCA1, RCA2, RCA3, and other radish seed proteins are phosphorylated by wheat embryo Ca(2+)-dependent protein kinase (CDPK). The RCA preparation contains other CDPK substrates in addition to RCA1, RCA2, and RCA3. The RCA preparation, RCA1, RCA2, and RCA3 inhibit chicken gizzard calmodulin-dependent myosin light chain kinase assayed with a myosin-light chain-based synthetic peptide substrate (fifty percent inhibitory concentrations of RCA2 and RCA3 are about 7 and 2 microM, respectively). N-terminal sequencing by sequential Edman degradation of RCA1, RCA2, and RCA3 revealed sequences having a high homology with the small subunit of the storage protein napin from Brassica napus and with related proteins. The deduced amino acid sequences of RCA1, RCA2, RCA3, and RCA3' (a subform of RCA3) have agreement with average molecular masses from electrospray mass spectrometry of 4537, 4543, 4532, and 4560 kD, respectively. The only sites for serine phosphorylation are near or at the C termini and hence adjacent to the sites of proteolytic precursor cleavage.

  15. The III working days of the Cenozoic

    International Nuclear Information System (INIS)

    2012-06-01

    The third working days in geology were organized by the Uruguayan Society of geology and took place in DINAMIGE in June - 2012. The lectures were given by national and foreign professionals and included important topics such as mineral raw materials used in the archaeological artifacts in Guayacas - Dayman - Paysandu . The Holocene in the coastal zone of Uruguay. Aspect of the early human occupation in Uruguay. Change effects in the land use about the mineral clay (eucalyptus forestation, illite). Paleoclimatic and paleoenvironmental reconstruction for middle and late holocene (Rocha). Gas hydrate resource quantification in Uruguay. Application of the geophysical techniques in the environmental pollution in Montevideo - Piriapolis. Environmental evolution and builders of small hills in India Muerta zone. Human or natural forcing in the geomorphological processes in Pocitos and Ramirez beaches (80 years of aerophotographic records).Tipology and nomenclature proposal for technological soil. Quarries reconditioning methodology. Hydraulic conductivity in sugar cane cultivated in soils previous vinaza application. Paleosoils and pedogenic calcretes formations in Fray Bentos (Oligocene - early miocene) Raigon (late pliocene and Middle pleistocene) and Libertad (early - middle pleistocene). Tectonics and sedimentary process in the continental talud in Uruguay. Rio de la Plata as paleoenvironmental focus using diatomos as proxies. Oleistocene mammals in the late-early Holocene in Santa Lucia river basin (Uruguay southern). Anthropization in Montevideo Bay during the Holocene. Paleocene stratigraphic plays in Uruguay offshore. Continental Influence versus marine transition in Rio de la Plata zone - internal continental shelf of the South Atlantic - a multiproxy study. Macrofossils vegetable in Palmar formation (later pleistocene) in Entre Rios - Argentina. Phytolith analysis in quaternary fluvial sediment (plio-pleistocene) in San Salvador and Palmar formation - Uruguay

  16. The plastid casein kinase 2 phosphorylates Rubisco activase at the Thr-78 site but is not essential for regulation of Rubisco activation state

    Science.gov (United States)

    Rubisco activase (RCA) is essential for the activation of Rubisco, the carboxylating enzyme of photosynthesis. In Arabidopsis, RCA is encoded by a single gene (At2g39730) that is alternatively spliced to form a large alpha-RCA and small beta-RCA isoform. The activity of Rubisco is controlled in res...

  17. Experience in energy, electricity and nuclear power planning with emphasis on MAED and WASP among Member States of the Regional Co-operative Agreement (RCA) in Asia and the Pacific Region

    International Nuclear Information System (INIS)

    1991-09-01

    This report includes the proceedings and papers of two workshops on energy, electricity and nuclear power planning: one held in Beijing, China, between 4-8 September 1989 (9 papers), and the other one held in Daejon, Republic of Korea, between 27-31 August 1990 (14 papers). A separate abstract was prepared for each of these papers. Refs, figs and tabs

  18. The use of mutant stock for semi-dwarf plant type and early maturity as cross-breeding materials in rice (coordinated programme on semi-dwarf mutants for rice improvement in Asia and the Pacific Region - RCA)

    International Nuclear Information System (INIS)

    Pookamana, P.

    1985-11-01

    Development of semi-dwarf type varieties has led to a substantial yield increase in Thailand, where rice is cultivated on areas of about 8 million hectars. Of 19 recommended Thai rice varieties, 10 possess the DGWG gene which determines semi-dwarf character. This situation can create some problems in terms of genetic vulnerability towards pests, diseases and other adverse stresses. The authors found that susceptibility to disease and insect pests as well as poor grain quality are major drawbacks associated with the DGWG gene. With this background, the major project goal was to obtain, by mutation techniques, a new genetic source of semi-dwarfness. For this purpose 3 tall local Thai varieties (Leaung Awn 29, Niaw Sanpah Tawng and Khao Dawk Mali) with very good grain quality, were chosen as parent material. Using radiation techniques 2 glutinous and 7 non-glutinous semi-dwarf mutants were obtained. Results of agronomic trials indicated that the mutants from local varieties were more promising and higher yielding in comparison to introduced varieties from IRRI, Taiwan, China, France and the USA. The preliminary genetics analysis of these mutants indicated an allelic relationship to the DGWG gene. This result is very important for the rice breeding programme because it made available the semi-dwarf gene in a new genetic background - with desirable characteristics for cultivation in Thailand. These positive results stimulated efforts to obtain new semi-dwarf mutants from other local, lowland rice varieties such as Leaung Tawang and Leb Mue Nahng 111. 49 and 35 semi-dwarf mutants were already selected after irradiation and are now under agronomic evaluation

  19. Co-ordinated research project on isotopic evaluations in infant growth monitoring - a collaboration with WHO (partly RCA). Report on the second and final research co-ordination meeting

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2004-07-01

    In the last few years, the World Health Organisation (WHO) has organised the development of new reference data for infant growth, reflecting the fact that previous growth reference data were based in part on formula-fed infants. With the benefits of breast-feeding for infant health increasingly recognised, and the differences in growth rate between breast-fed and formula-fed infants replicated in many populations, growth reference data from breast-fed infants became a priority. The importance of early growth for adult health is also increasingly appreciated, with numerous studies linking early nutrition and growth patterns to the risk of cardiovascular disease, obesity, type 2 diabetes and stroke in later life. To support these new reference data, it is also important to assess the breast-milk and nutrient intakes of normally-growing breast-fed infants, in order to revise recommendations for their energy requirements. This coordinated research project (CRP) was therefore initiated by the International Atomic Energy Agency to investigate milk intake and growth in several populations from developing countries. A secondary aim was to continue the technological development of methodologies that allow the required measurements to be undertaken in free-living mother-infant pairs in field conditions. The measurement of breast-milk intake was until recently undertaken using test-weighing, whereby the infant is weighed before and after each feed during one or more 24 hour periods. This method is intrusive, cumbersome, and unsuitable for many populations under field conditions. The development of the dose-to-the-mother deuterium oxide turnover method, by which maternal breast-milk transfer can be assessed by isotopic kinetics, has transformed the ability to measure milk intake in wholly or partially breast-fed infants in developing countries. The current CRP aimed to apply this technology to a variety of populations, ensuring that the data were comparable between countries through establishment of a standardised protocol. The participating countries in this CRP were Bangladesh, Brazil, Chile and Pakistan for the measurement of growth and breast-milk intake. These countries, currently undergoing nutritional transition, all have active programmes for the promotion of breast-feeding. Results of the studies from Brazil, Chile and Pakistan were discussed during this final Research Coordination Meeting (RCM). Technological aspects of the measurements, with a view to future applications, were also discussed.

  20. Co-ordinated research project on isotopic evaluations in infant growth monitoring - a collaboration with WHO (partly RCA). Report on the second and final research co-ordination meeting

    International Nuclear Information System (INIS)

    2004-01-01

    In the last few years, the World Health Organisation (WHO) has organised the development of new reference data for infant growth, reflecting the fact that previous growth reference data were based in part on formula-fed infants. With the benefits of breast-feeding for infant health increasingly recognised, and the differences in growth rate between breast-fed and formula-fed infants replicated in many populations, growth reference data from breast-fed infants became a priority. The importance of early growth for adult health is also increasingly appreciated, with numerous studies linking early nutrition and growth patterns to the risk of cardiovascular disease, obesity, type 2 diabetes and stroke in later life. To support these new reference data, it is also important to assess the breast-milk and nutrient intakes of normally-growing breast-fed infants, in order to revise recommendations for their energy requirements. This coordinated research project (CRP) was therefore initiated by the International Atomic Energy Agency to investigate milk intake and growth in several populations from developing countries. A secondary aim was to continue the technological development of methodologies that allow the required measurements to be undertaken in free-living mother-infant pairs in field conditions. The measurement of breast-milk intake was until recently undertaken using test-weighing, whereby the infant is weighed before and after each feed during one or more 24 hour periods. This method is intrusive, cumbersome, and unsuitable for many populations under field conditions. The development of the dose-to-the-mother deuterium oxide turnover method, by which maternal breast-milk transfer can be assessed by isotopic kinetics, has transformed the ability to measure milk intake in wholly or partially breast-fed infants in developing countries. The current CRP aimed to apply this technology to a variety of populations, ensuring that the data were comparable between countries through establishment of a standardised protocol. The participating countries in this CRP were Bangladesh, Brazil, Chile and Pakistan for the measurement of growth and breast-milk intake. These countries, currently undergoing nutritional transition, all have active programmes for the promotion of breast-feeding. Results of the studies from Brazil, Chile and Pakistan were discussed during this final Research Coordination Meeting (RCM). Technological aspects of the measurements, with a view to future applications, were also discussed

  1. Relatório de estágio : experiência nas equipas de Cuidados domiciliários com suporte paliativo – Equipa de Cuidados Continuados Integrados do Centro de Saúde de Odivelas, Unidade de apoio Domiciliário do IPOFGL e Unidade de Cuidados Paliativos S. Bento Menni - Casa de Saúde da Idanha - Belas

    OpenAIRE

    Lopes, Maria João Rebelo

    2012-01-01

    Trabalhar em Cuidados Paliativos implica desenvolver uma actividade em equipa transdisciplinar com uma partilha constante de conhecimento entre todos os elementos. Abordar as necessidades globais do doente e família, disponibilizando ajuda de todos os profissionais ao longo da evolução da doença é fundamental para que a prestação de cuidados seja feita com qualidade. Para a concretização desse objectivo é importante que a equipa valorize e invista na formação e treino dos seus elementos. D...

  2. Reduction of Gender and Institutional Violence against ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    These include the Associación Equipo de Estudios Comunitarios y Acción Psicosocial (Association of Community Studies and Psychosocial Action Team) in Guatemala, Centro de Derechos Humanos Fray Matías de Córdova A.C (Fray Matias Centre for Human Rights of Cordova) in Mexico, and the Voces Mesoamericanas ...

  3. Evolution des caractéristiques physico-chimiques de deux zones de frayères à sédimentation contrastée et premiers résultats de survie embryo-larvaire de truite commune (Salmo trutta

    Directory of Open Access Journals (Sweden)

    MASSA F.

    1998-07-01

    Full Text Available L'impact chimique et physique de la sédimentation sur la survie d'oeufs de Salmonidés a été étudié dans la partie amont de deux ruisseaux d'un même bassin à production salmonicole contrastée : le Moulinet qui présente une faible population de truites et la Roche qui est un ruisseau très productif. Les matières en suspension et les sédiments déposés ont été collectés à un pas de temps de 8 ou 15 jours en 1996 et 1997 et les survies embryo-larvaires ont été estimées en parallèle, dans des incubateurs artificiels. Les taux de survie ont été déterminés à l'émergence en 1996 et de la fécondation à l'éclosion, puis de l'éclosion à l'émergence en 1997. Les paramètres chimiques de l'eau interstitielle (oxygène, pH, nitrates, nitrites et ammoniac ont été mesurés au pas de temps de la semaine pendant la période d'incubation 1997 sur des dispositifs enfouis dans le substrat du ruisseau et au moment de l'éclosion dans les incubateurs contenant les oeufs. Les premiers résultats montrent que les taux de survie embryo-larvaires sont nuls en 1996 et faibles en 1997 (0 à 11 %, moyenne : 3,3 % dans le ruisseau du Moulinet alors que parallèlement, la survie est de 20 % sur un incubateur en 1996 et varie de 0 à 23 % en 1997 (moyenne : 7,7 % dans le ruisseau de la Roche. De l'éclosion à l'émergence, les survies sont supérieures à 80 % dans les deux ruisseaux. La sédimentation est contrastée sur les deux sites, plus forte en masse dans le ruisseau de la Roche pendant la période d'incubation mais de granulométrie beaucoup plus grossière que dans le ruisseau du Moulinet (sableuse dominante contre argilolimoneuse. Les teneurs en oxygène dissous mesurées dans le substrat de la Roche restent élevées pendant toute la période d'incubation (teneur minimum de 5 mg/l et sont significativement supérieures à celles mesurées dans le ruisseau du Moulinet pendant la deuxième partie de l'incubation 1997. D'autre part, les teneurs en nitrates sont équivalentes à celles de l'eau de surface pour la Roche alors qu'elles sont significativement différentes de l'eau de surface pour le Moulinet. Les concentrations en nitrites et ammoniac recensées sont au maximum de 12,9 µg/l de N-NO2 et 2 µg/l de N-NH4 sur le Moulinet et de 11,4 µg/l de N-NO2 et 1,4 µg/l de N-NH4 pour la Roche. Les mortalités plus élevées sur le site du Moulinet pourraient être dues à une synergie de facteurs défavorables présents dans le milieu tels que la présence de faibles teneurs en oxygène et de nitrites, comme cela a été reporté dans la littérature pour des poissons adultes.

  4. Alographia dos álkalis... de Frei Conceição Veloso: um manual de química industrial para produção da potassa no Brasil colonial The production of potash from plants in colonial Brazil as described in fray Conceição Veloso's Alographia dos alkalis...

    Directory of Open Access Journals (Sweden)

    Fernando J. Luna

    2008-01-01

    Full Text Available Potassium carbonate, or potash, was the most important industrial chemical of the 18th century. It was essential for producing glass, soap, saltpeter, dyes, several drugs, and also used for bleaching linens, paper, and sugar. We examine here a book in which Brazilian author José Mariano da Conceição Veloso gathered his translations into Portuguese of English and French articles, letters, patents, and pamphlets with instructions on how to prepare potash. We discuss especially his version of Richard Watson's essay entitled 'Of saline substances', and Veloso's own 'Flora Alographica', a description of the Brazilian plants that could be used to prepare potash.

  5. A comparison of two least-squared random coefficient autoregressive models: with and without autocorrelated errors

    OpenAIRE

    Autcha Araveeporn

    2013-01-01

    This paper compares a Least-Squared Random Coefficient Autoregressive (RCA) model with a Least-Squared RCA model based on Autocorrelated Errors (RCA-AR). We looked at only the first order models, denoted RCA(1) and RCA(1)-AR(1). The efficiency of the Least-Squared method was checked by applying the models to Brownian motion and Wiener process, and the efficiency followed closely the asymptotic properties of a normal distribution. In a simulation study, we compared the performance of RCA(1) an...

  6. Laboratory evaluation of recycled concrete as aggregate in new concrete pavements.

    Science.gov (United States)

    2014-09-01

    The Washington State Department of Transportation (WSDOT) has initiated a research project to investigate the use of recycled concrete as : aggregates (RCA) in Portland (hydraulic) cement concrete pavements (PCCP). The planned source for the RCA in t...

  7. Efficient use of recycled concrete in transportation infrastructure

    Science.gov (United States)

    2011-01-21

    This study examined current national and international practices regarding the use of recycled concrete aggregates (RCA) as engineering materials by the transportation industry as well as a history of Michigan's experience with RCA. In the laboratory...

  8. Recycled concrete aggregate in portland cement concrete.

    Science.gov (United States)

    2013-01-01

    Aggregates can be produced by crushing hydraulic cement concrete and are known as recycled concrete : aggregates (RCA). This report provides results from a New Jersey Department of Transportation study to identify : barriers to the use of RCA in new ...

  9. Identification of the First Riboflavin Catabolic Gene Cluster Isolated from Microbacterium maritypicum G10*

    OpenAIRE

    Xu, Hui; Chakrabarty, Yindrila; Philmus, Benjamin; Mehta, Angad P.; Bhandari, Dhananjay; Hohmann, Hans-Peter; Begley, Tadhg P.

    2016-01-01

    Riboflavin is a common cofactor, and its biosynthetic pathway is well characterized. However, its catabolic pathway, despite intriguing hints in a few distinct organisms, has never been established. This article describes the isolation of a Microbacterium maritypicum riboflavin catabolic strain, and the cloning of the riboflavin catabolic genes. RcaA, RcaB, RcaD, and RcaE were overexpressed and biochemically characterized as riboflavin kinase, riboflavin reductase, ribokinase, and riboflavin ...

  10. In Vitro Characterization of Thermostable CAM Rubisco Activase Reveals a Rubisco Interacting Surface Loop1[OPEN

    Science.gov (United States)

    Shivhare, Devendra

    2017-01-01

    To maintain metabolic flux through the Calvin-Benson-Bassham cycle in higher plants, dead-end inhibited complexes of Rubisco must constantly be engaged and remodeled by the molecular chaperone Rubisco activase (Rca). In C3 plants, the thermolability of Rca is responsible for the deactivation of Rubisco and reduction of photosynthesis at moderately elevated temperatures. We reasoned that crassulacean acid metabolism (CAM) plants must possess thermostable Rca to support Calvin-Benson-Bassham cycle flux during the day when stomata are closed. A comparative biochemical characterization of rice (Oryza sativa) and Agave tequilana Rca isoforms demonstrated that the CAM Rca isoforms are approximately10°C more thermostable than the C3 isoforms. Agave Rca also possessed a much higher in vitro biochemical activity, even at low assay temperatures. Mixtures of rice and agave Rca form functional hetero-oligomers in vitro, but only the rice isoforms denature at nonpermissive temperatures. The high thermostability and activity of agave Rca mapped to the N-terminal 244 residues. A Glu-217-Gln amino acid substitution was found to confer high Rca activity to rice Rca. Further mutational analysis suggested that Glu-217 restricts the flexibility of the α4-β4 surface loop that interacts with Rubisco via Lys-216. CAM plants thus promise to be a source of highly functional, thermostable Rca candidates for thermal fortification of crop photosynthesis. Careful characterization of their properties will likely reveal further protein-protein interaction motifs to enrich our mechanistic model of Rca function. PMID:28546437

  11. Far East Asia | Page 87 | IDRC - International Development ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Although economic progress has reduced poverty, the region still suffers from important challenges such as inequities, violence targeting minorities, environmental depletion, growing informal employment, and food insecurity. These pressures strain the infrastructure and fray human relations, ultimately hampering ...

  12. South Asia | Page 192 | IDRC - International Development Research ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Although economic growth has reduced poverty in much of Asia, rural and ... These pressures strain the infrastructure and fray human relations, ultimately hampering development. ... Our regional office for Asia is located in New Delhi, India.

  13. South Asia | Page 191 | IDRC - International Development Research ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Although economic growth has reduced poverty in much of Asia, rural and ... These pressures strain the infrastructure and fray human relations, ultimately hampering development. ... Our regional office for Asia is located in New Delhi, India.

  14. South Asia | Page 195 | IDRC - International Development Research ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Although economic growth has reduced poverty in much of Asia, rural and ... These pressures strain the infrastructure and fray human relations, ultimately hampering development. ... Our regional office for Asia is located in New Delhi, India.

  15. Far East Asia | Page 182 | IDRC - International Development ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Although economic growth has reduced poverty in much of Asia, rural and ... These pressures strain the infrastructure and fray human relations, ultimately hampering development. ... Our regional office for Asia is located in New Delhi, India.

  16. Application Actuation Trade Study

    Science.gov (United States)

    1982-01-01

    32 RCA PRICE-L Podel Calculated 0 & S Values 138 33 RCA PRICE LCC Summery - Typical LRU 139 34 Airplane Actuation Trade Study LCC Summary 140 35...results achieved can be duplicated by a user. The RCA PRICE Podel calculates the RDTSE. Production cost, and creates the YiDF file for use in the PCA...PR ICE L). Some of the basic program ground rules for this study were as follows: RCA - PRICE Cost Podel RCA - PRICE L Model Prototype Hardware 10

  17. Réduction de la violence sexospécifique et institutionnelle envers ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Parmi ces organisations et institutions, on compte l'association Equipo de Estudios Comunitarios y Acción Psicosocial (Équipe d'études communautaires et d'action psychosociale) au Guatemala, le Centro de Derechos Humanos Fray Matías de Córdova A.C (Centre des droits humains Fray Matías de Córdova) au Mexique ...

  18. Enhanced Thermostability of Arabidopsis Rubisco Activase Improves Photosynthesis and Growth Rates under Moderate Heat Stress[OA

    Science.gov (United States)

    Kurek, Itzhak; Chang, Thom Kai; Bertain, Sean M.; Madrigal, Alfredo; Liu, Lu; Lassner, Michael W.; Zhu, Genhai

    2007-01-01

    Plant photosynthesis declines when the temperature exceeds its optimum range. Recent evidence indicates that the reduction in photosynthesis is linked to ribulose-1,5-bis-phosphate carboxylase/oxygenase (Rubisco) deactivation due to the inhibition of Rubisco activase (RCA) under moderately elevated temperatures. To test the hypothesis that thermostable RCA can improve photosynthesis under elevated temperatures, we used gene shuffling technology to generate several Arabidopsis thaliana RCA1 (short isoform) variants exhibiting improved thermostability. Wild-type RCA1 and selected thermostable RCA1 variants were introduced into an Arabidopsis RCA deletion (Δrca) line. In a long-term growth test at either constant 26°C or daily 4-h 30°C exposure, the transgenic lines with the thermostable RCA1 variants exhibited higher photosynthetic rates, improved development patterns, higher biomass, and increased seed yields compared with the lines expressing wild-type RCA1 and a slight improvement compared with untransformed Arabidopsis plants. These results provide clear evidence that RCA is a major limiting factor in plant photosynthesis under moderately elevated temperatures and a potential target for genetic manipulation to improve crop plants productivity under heat stress conditions. PMID:17933901

  19. Deformation Behavior of Recycled Concrete Aggregate during Cyclic and Dynamic Loading Laboratory Tests

    Directory of Open Access Journals (Sweden)

    Wojciech Sas

    2016-09-01

    Full Text Available Recycled concrete aggregate (RCA is a relatively new construction material, whose applications can replace natural aggregates. To do so, extensive studies on its mechanical behavior and deformation characteristics are still necessary. RCA is currently used as a subbase material in the construction of roads, which are subject to high settlements due to traffic loading. The deformation characteristics of RCA must, therefore, be established to find the possible fatigue and damage behavior for this new material. In this article, a series of triaxial cyclic loading and resonant column tests is used to characterize fatigue in RCA as a function of applied deviator stress after long-term cyclic loading. A description of the shakedown phenomenon occurring in the RCA and calculations of its resilient modulus (Mr as a function of fatigue are also presented. Test result analysis with the stress-life method on the Wohler S-N diagram shows the RCA behavior in accordance with the Basquin law.

  20. Performance Evaluation of Stone Mastic Asphalt and Hot Mix Asphalt Mixtures Containing Recycled Concrete Aggregate

    Directory of Open Access Journals (Sweden)

    Mohammad Saeed Pourtahmasb

    2014-01-01

    Full Text Available Environmental and economic considerations have encouraged civil engineers to find ways to reuse recycled materials in new constructions. The current paper presents an experimental research on the possibility of utilizing recycled concrete aggregates (RCA in stone mastic asphalt (SMA and hot mix asphalt (HMA mixtures. Three categories of RCA in various percentages were mixed with virgin granite aggregates to produce SMA and HMA specimens. The obtained results indicated that, regardless of the RCA particular sizes, the use of RCA to replace virgin aggregates increased the needed binder content in the asphalt mixtures. Moreover, it was found that even though the volumetric and mechanical properties of the asphalt mixtures are highly affected by the sizes and percentages of the RCA but, based on the demands of the project and traffic volume, utilizing specific amounts of RCA in both types of mixtures could easily satisfy the standard requirements.

  1. In Vitro Characterization of Thermostable CAM Rubisco Activase Reveals a Rubisco Interacting Surface Loop.

    Science.gov (United States)

    Shivhare, Devendra; Mueller-Cajar, Oliver

    2017-07-01

    To maintain metabolic flux through the Calvin-Benson-Bassham cycle in higher plants, dead-end inhibited complexes of Rubisco must constantly be engaged and remodeled by the molecular chaperone Rubisco activase (Rca). In C3 plants, the thermolability of Rca is responsible for the deactivation of Rubisco and reduction of photosynthesis at moderately elevated temperatures. We reasoned that crassulacean acid metabolism (CAM) plants must possess thermostable Rca to support Calvin-Benson-Bassham cycle flux during the day when stomata are closed. A comparative biochemical characterization of rice ( Oryza sativa ) and Agave tequilana Rca isoforms demonstrated that the CAM Rca isoforms are approximately10°C more thermostable than the C3 isoforms. Agave Rca also possessed a much higher in vitro biochemical activity, even at low assay temperatures. Mixtures of rice and agave Rca form functional hetero-oligomers in vitro, but only the rice isoforms denature at nonpermissive temperatures. The high thermostability and activity of agave Rca mapped to the N-terminal 244 residues. A Glu-217-Gln amino acid substitution was found to confer high Rca activity to rice Rca Further mutational analysis suggested that Glu-217 restricts the flexibility of the α4-β4 surface loop that interacts with Rubisco via Lys-216. CAM plants thus promise to be a source of highly functional, thermostable Rca candidates for thermal fortification of crop photosynthesis. Careful characterization of their properties will likely reveal further protein-protein interaction motifs to enrich our mechanistic model of Rca function. © 2017 American Society of Plant Biologists. All Rights Reserved.

  2. Myocardial ischemia due to compression of an unruptured thoracic aortic aneurysm in a patient with Marfan syndrome.

    Science.gov (United States)

    Minami, Hiroya; Asada, Tatsuro; Gan, Kunio; Abe, Koichiro; Izumi, Satoshi

    2007-06-01

    We report a 33-year-old woman who had a 60-mm thoracic aneurysm of the ascending aorta with Marfan syndrome and effort angina due to compression of the right coronary artery (RCA) by the aneurysm. Surgery was performed using the Bentall procedure and a coronary artery bypass graft to the RCA. Postoperatively, coronary angiography showed that the coronary flow of the RCA was restored by removing the aneurysmal compression. The patient was discharged without angina on postoperative day 21.

  3. Rolling circle amplification of metazoan mitochondrialgenomes

    Energy Technology Data Exchange (ETDEWEB)

    Simison, W. Brian; Lindberg, D.R.; Boore, J.L.

    2005-07-31

    Here we report the successful use of rolling circle amplification (RCA) for the amplification of complete metazoan mt genomes to make a product that is amenable to high-throughput genome sequencing techniques. The benefits of RCA over PCR are many and with further development and refinement of RCA, the sequencing of organellar genomics will require far less time and effort than current long PCR approaches.

  4. Root cortical aerenchyma inhibits radial nutrient transport in maize (Zea mays).

    Science.gov (United States)

    Hu, Bo; Henry, Amelia; Brown, Kathleen M; Lynch, Jonathan P

    2014-01-01

    Formation of root cortical aerenchyma (RCA) can be induced by nutrient deficiency. In species adapted to aerobic soil conditions, this response is adaptive by reducing root maintenance requirements, thereby permitting greater soil exploration. One trade-off of RCA formation may be reduced radial transport of nutrients due to reduction in living cortical tissue. To test this hypothesis, radial nutrient transport in intact roots of maize (Zea mays) was investigated in two radiolabelling experiments employing genotypes with contrasting RCA. In the first experiment, time-course dynamics of phosphate loading into the xylem were measured from excised nodal roots that varied in RCA formation. In the second experiment, uptake of phosphate, calcium and sulphate was measured in seminal roots of intact young plants in which variation in RCA was induced by treatments altering ethylene action or genetic differences. In each of three paired genotype comparisons, the rate of phosphate exudation of high-RCA genotypes was significantly less than that of low-RCA genotypes. In the second experiment, radial nutrient transport of phosphate and calcium was negatively correlated with the extent of RCA for some genotypes. The results support the hypothesis that RCA can reduce radial transport of some nutrients in some genotypes, which could be an important trade-off of this trait.

  5. Enhanced Thermostability of Arabidopsis Rubisco activase improves photosynthesis and growth rates under moderate heat stress.

    Science.gov (United States)

    Kurek, Itzhak; Chang, Thom Kai; Bertain, Sean M; Madrigal, Alfredo; Liu, Lu; Lassner, Michael W; Zhu, Genhai

    2007-10-01

    Plant photosynthesis declines when the temperature exceeds its optimum range. Recent evidence indicates that the reduction in photosynthesis is linked to ribulose-1,5-bis-phosphate carboxylase/oxygenase (Rubisco) deactivation due to the inhibition of Rubisco activase (RCA) under moderately elevated temperatures. To test the hypothesis that thermostable RCA can improve photosynthesis under elevated temperatures, we used gene shuffling technology to generate several Arabidopsis thaliana RCA1 (short isoform) variants exhibiting improved thermostability. Wild-type RCA1 and selected thermostable RCA1 variants were introduced into an Arabidopsis RCA deletion (Deltarca) line. In a long-term growth test at either constant 26 degrees C or daily 4-h 30 degrees C exposure, the transgenic lines with the thermostable RCA1 variants exhibited higher photosynthetic rates, improved development patterns, higher biomass, and increased seed yields compared with the lines expressing wild-type RCA1 and a slight improvement compared with untransformed Arabidopsis plants. These results provide clear evidence that RCA is a major limiting factor in plant photosynthesis under moderately elevated temperatures and a potential target for genetic manipulation to improve crop plants productivity under heat stress conditions.

  6. Identification of the First Riboflavin Catabolic Gene Cluster Isolated from Microbacterium maritypicum G10.

    Science.gov (United States)

    Xu, Hui; Chakrabarty, Yindrila; Philmus, Benjamin; Mehta, Angad P; Bhandari, Dhananjay; Hohmann, Hans-Peter; Begley, Tadhg P

    2016-11-04

    Riboflavin is a common cofactor, and its biosynthetic pathway is well characterized. However, its catabolic pathway, despite intriguing hints in a few distinct organisms, has never been established. This article describes the isolation of a Microbacterium maritypicum riboflavin catabolic strain, and the cloning of the riboflavin catabolic genes. RcaA, RcaB, RcaD, and RcaE were overexpressed and biochemically characterized as riboflavin kinase, riboflavin reductase, ribokinase, and riboflavin hydrolase, respectively. Based on these activities, a pathway for riboflavin catabolism is proposed. © 2016 by The American Society for Biochemistry and Molecular Biology, Inc.

  7. Identification of the First Riboflavin Catabolic Gene Cluster Isolated from Microbacterium maritypicum G10*

    Science.gov (United States)

    Xu, Hui; Chakrabarty, Yindrila; Philmus, Benjamin; Mehta, Angad P.; Bhandari, Dhananjay; Hohmann, Hans-Peter; Begley, Tadhg P.

    2016-01-01

    Riboflavin is a common cofactor, and its biosynthetic pathway is well characterized. However, its catabolic pathway, despite intriguing hints in a few distinct organisms, has never been established. This article describes the isolation of a Microbacterium maritypicum riboflavin catabolic strain, and the cloning of the riboflavin catabolic genes. RcaA, RcaB, RcaD, and RcaE were overexpressed and biochemically characterized as riboflavin kinase, riboflavin reductase, ribokinase, and riboflavin hydrolase, respectively. Based on these activities, a pathway for riboflavin catabolism is proposed. PMID:27590337

  8. Rubisco Activase Is Also a Multiple Responder to Abiotic Stresses in Rice.

    Directory of Open Access Journals (Sweden)

    Yue Chen

    Full Text Available Ribulose-1,5-bisphosphate carboxylase/oxygenase activase (RCA is a nuclear gene that encodes a chloroplast protein that plays an important role in photosynthesis. Some reports have indicated that it may play a role in acclimation to different abiotic stresses. In this paper, we analyzed the stress-responsive elements in the 2.0 kb 5'-upstream regions of the RCA gene promoter and the primary, secondary and tertiary structure of the protein. We identified some cis-elements of multiple stress-related components in the RCA promoter. Amino acid and evolution analyses showed that the RCA protein had conserved regions between different species; however, the size and type varied. The secondary structures, binding sites and tertiary structures of the RCA proteins were also different. This might reflect the differences in the transcription and translation levels of the two RCA isoforms during adaptation to different abiotic stresses. Although both the transcription and translation levels of RCA isoforms in the rice leaves increased under various stresses, the large isoform was increased more significantly in the chloroplast stroma and thylakoid. It can be concluded that RCA, especially RCAL, is also a multiple responder to abiotic stresses in rice, which provides new insights into RCA functions.

  9. Design and Development Comparison of Rapid Cycle Amine 1.0, 2.0, and 3.0

    Science.gov (United States)

    Chullen, Cinda; Campbell, Colin; Papale, William; Murray, Sean; Wichowski, Robert; Conger, Bruce; McMillin, Summer

    2016-01-01

    The development of the Rapid Cycle Amine (RCA) swing-bed technology for carbon dioxide (CO2) removal has been in progress since favorable results were published in 1996. Shortly thereafter, a prototype was designed, developed, and tested successfully and delivered to Johnson Space Center in 1999. An improved prototype (RCA 1.0) was delivered to NASA in 2006 and sized for the extravehicular activity (EVA). The RCA swing-bed technology is a regenerative system which employs two alternating solid-amine sorbent beds to remove CO2 and water. The two-bed design employs a chemisorption process whereby the beds alternate between adsorption and desorption. This process provides for an efficient RCA operation that enables one bed to be in adsorb (uptake) mode, while the other is in the desorb (regeneration) mode. The RCA has progressed through several iterations of technology readiness levels. Test articles have now been designed, developed, and tested for the advanced space suit portable life support system (PLSS) including RCA 1.0, RCA 2.0, and RCA 3.0. The RCA 3.0 was the most recent RCA fabrication and was delivered to NASA-JSC in June 2015. The RCA 1.0 test article was designed with a pneumatically actuated linear motion spool valve. The RCA 2.0 and 3.0 test articles were designed with a valve assembly which allows for switching between uptake and regeneration modes while minimizing gas volume losses to the vacuum source. RCA 2.0 and 3.0 also include an embedded controller design to control RCA operation and provide the capability of interfacing with various sensors and other ventilation loop components. The RCA technology is low power, small, and has fulfilled all test requirements levied upon the technology during development testing thus far. This paper will provide an overview of the design and development of RCA 1.0, 2.0 and 3.0 including detail differences between the design specifications of each. Nomenclature.

  10. The methodology of root cause analysis for equipment failure and its application at Guangdong nuclear power stations

    International Nuclear Information System (INIS)

    Gao Ligang; Lu Qunxian

    2004-01-01

    The methodology of Equipment Failure Root Cause Analysis (RCA) is described, as a systematic analysis methodology, it includes 9 steps. Its process is explained by some real examples, and the 6 precautions applying RCA is pointed out. The paper also summarizes the experience of RCA application at Daya Bay Nuclear Power Station, and the 7 key factors for RCA success is emphasized, that mainly concerns organization, objective, analyst, analysis technique, external technical supporting system, corrective actions developing and monitoring system for corrective actions. (authors)

  11. Evaluation of genetic diversity of Portuguese Pinus sylvestris L.

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Genetics; Volume 92; Online resources. Evaluation of genetic diversity of Portuguese Pinus sylvestris L. populations based on molecular data and inferences about the future use of this germplasm. J. Cipriano A. Carvalho C. Fernandes M. J. Gaspar J. Pires J. Bento L. Roxo J. Louzada J. Lima- ...

  12. A invenção das categorias travesti e transexual no discurso científico

    Directory of Open Access Journals (Sweden)

    Melissa Barbieri de Oliveira

    2014-05-01

    Full Text Available LEITE JR., Jorge. Apresentação: Berenice Bento. Nossos corpos também mudam: a invenção das categorias “travesti” e “transexual” no discurso científico. São Paulo: Annablume, 2011. 240 p.

  13. SPATIAL AND TEMPORAL DISTRIBUTION OF Concholepas Concholepas (GASTROPODA, MURICIDAE) VELIGER LARVAE IN THE INLAND SEAS OF NORTHWEST PATAGONIA.

    OpenAIRE

    MOLINET FLORES, CARLOS ALBERTO; MOLINET FLORES, CARLOS ALBERTO

    2005-01-01

    El presente estudio fue enfocado sobre la base de la hipótesis que el desarrollo larval extracapsular de C. concholepas ocurre en aguas profundas cerca del bentos y que larvas competentes de esta especie son transportadas a la superficie por mecanismos fí 124p.

  14. Is right coronary artery chronic total vessel occlusion impacting the surgical revascularization results of patients with multivessel disease? A retrospective study

    Directory of Open Access Journals (Sweden)

    Janusz Konstanty-Kalandyk

    2018-06-01

    Full Text Available Introduction Chronic total occlusion (CTO is common in the presence of other significantly narrowed coronary arteries. The impact of total occlusion and its association with completeness of revascularization on patients with multivessel disease undergoing coronary artery bypass graft (CABG remains largely unknown. Aim The aim of our study was to compare CABG operation characteristics, as well as 30-day mortality, incidence of post-operative major adverse cardiac and cerebrovascular events (MACCE between patients with and without CTO in right coronary artery (RCA. Materials and Methods A total of 156 consecutive patients were included in the analysis. CTO of RCA or right posterior descending artery (RPD was diagnosed in 57 patients (CTO-RCA group. Coronary stenosis without CTO in RCA was diagnosed in 99 patients (nonCTO-RCA group. Baseline characteristics were comparable in both groups. Results The majority of patients had class II (49.1% vs. 46%, p = 0.86 or class III (42.1% vs. 43%, p = 1.0 Canadian Cardiovascular Society grading system symptoms. Patients in the CTO-RCA group had in average 2.2 grafts implanted, as opposed to 2.4 grafts in patients in the nonCTO-RCA group (p = 0.003. Graft to the RCA was performed in 40.3% patients in the CTO-RCA group and in 81% patients in the nonCTO-RCA group (p = 0.001. The 30-day mortality from any cause or cardiac cause did not differ between groups (7% vs. 2%, p = 0.14 and 3.5% vs. 2%, p = 0.57 respectively. In a multivariate analysis CTO in RCA or RPD and peripheral artery disease were independent predictors of post-operative MACCE (7.9 (1.434–43.045 p = 0.02; 18.8 (3.451–101.833 p < 0.01, respectively. Conclusions Chronic total occlusion of RCA was found to be associated with smaller number of grafts performed during the CABG procedure. Although mortality between patients in the CTO-RCA and nonCTO-RCA groups did not differ, patients in the CTO-RCA group had higher incidence of post-operative MACCE.

  15. Training health care professionals in root cause analysis: a cross-sectional study of post-training experiences, benefits and attitudes

    Directory of Open Access Journals (Sweden)

    Bowie Paul

    2013-02-01

    Full Text Available Abstract Background Root cause analysis (RCA originated in the manufacturing engineering sector but has been adapted for routine use in healthcare to investigate patient safety incidents and facilitate organizational learning. Despite the limitations of the RCA evidence base, healthcare authorities and decision makers in NHS Scotland – similar to those internationally - have invested heavily in developing training programmes to build local capacity and capability, and this is a cornerstone of many organizational policies for investigating safety-critical issues. However, to our knowledge there has been no systematic attempt to follow-up and evaluate post-training experiences of RCA-trained staff in Scotland. Given the significant investment in people, time and funding we aimed to capture and learn from the reported experiences, benefits and attitudes of RCA-trained staff and the perceived impact on healthcare systems and safety. Methods We adapted a questionnaire used in a published Australian research study to undertake a cross sectional online survey of health care professionals (e.g. nursing & midwifery, medical doctors and pharmacists formally trained in RCA by a single territorial health board region in NHS Scotland. Results A total of 228/469 of invited staff completed the survey (48%. A majority of respondents had yet to participate in a post-training RCA investigation (n=127, 55.7%. Of RCA-experience staff, 71 had assumed a lead investigator role (70.3% on one or more occasions. A clear majority indicated that their improvement recommendations were generally or partly implemented (82%. The top three barriers to RCA success were cited as: lack of time (54.6%, unwilling colleagues (34% and inter-professional differences (31%. Differences in agreement levels between RCA-experienced and inexperienced respondents were noted on whether a follow-up session would be beneficial after conducting RCA (65.3% v 39.4% and if peer feedback on RCA

  16. The addition of a pH-sensitive gel improves microemulsion stability for the targeted removal of colonic ammonia

    Directory of Open Access Journals (Sweden)

    Zhang Wen-Jun

    2011-05-01

    Full Text Available Abstract Background We prepared an oral W/O microemulsion for the removal of colonic ammonia (ME-RCA. The effect of this microemulsion was influenced by the digestion process in the gastrointestinal tract. In this paper, we aim to show that stability was improved by using a microemulsion-based gel for the removal of colonic ammonia (MBG-RCA. Methods MBG-RCA was prepared by adding sodium alginate to the ME-RCA. MBG-RCA and ME-RCA were passed through a simulated gastrointestinal environment, and the amount of colonic ammonia present was then determined by titration with a standard solution of hydrochloric acid. The pH of the gastrointestinal fluid was measured using a pH test paper and the size and form of the microemulsions were examined under the microscope. 18 healthy rats were randomly divided into three groups, fasted for 24 hours and allowed to drink normally. Three-way pipes were placed at the gastroduodenal junction in Group I, and at the terminal ileum in Group II. After the intragastric administration of ME-RCA, the stomach contents in Group I, the effluent from the terminal ileum in Group II and discharge from the anus in Group III were collected. The pH values of the gastrointestinal juice were measured by the pH test paper and those of the colon were determined by a universal indicator. These animal experiments were also used to test the effect of MBG-RCA. Results MBG-RCA showed a better removal rate of artificial colonic ammonia than ME-RCA (P Conclusions MBG-RCA was more stable in the gastrointestinal tract and more effective at removing colonic ammonia when a higher concentration of ammonia was present. This made it possible to achieve the targeted removal of colonic ammonia and is a promising method to prevent hepatic encephalopathy (HE in future studies.

  17. Response of right ventricular ejection fraction to exercise stress in coronary artery disease

    International Nuclear Information System (INIS)

    Narita, Michihiro; Kurihara, Tadashi; Murano, Kenichi; Usami, Masahisa

    1985-01-01

    The right ventricular (RV) response to exercise was assessed in 28 patients with coronary artery disease (CAD) and 9 normal subjects. The relationship between RV reserve, exercise left ventricular (LV) reserve and the presence of proximal right coronary artery (RCA) stenosis were evaluated. RV and LV ejection fraction (EF) were determined by multiple-gated equilibrium blood pool imaging with sup(99m)Tc in the modified left anterior oblique position. Graded supine exercise stress blood pool imaging was performed at the same position by using bicycle ergometer. For calculation of RVEF, variable ROIs were used. In normal subjects, both RVEF and LVEF increased significantly during exercise (%ΔRVEF 18.9+-5.9%, %ΔLVEF 16.3%+-4.7%). In CAD groups with and without RCA stenosis, LVEF and RVEF showed decrease or no change during exercise. Although magnitude of change in LVEF from rest to exercise (%ΔLVEF) was not significantly different in both CAD groups (4.1+-9.0% in cases with RCA disease and 6.2+-14.6% in cases without RCA disease), %ΔRVEF was different significantly (16.0+-14.3% in cases with RCA disease and 1.4+-14.1% in cases without RCA disease, p<0.05). In patients with RCA disease, 3 patients (25%) showed depression in RVEF with exercise regardless of the increase in LVEF. However, none of the patients without RCA disease showed depression in RVEF with the increment in LVEF during exercise. These findings suggested that proximal RCA stenosis is one major determinant of exercise RVEF response. But in 9 of 16 patients without RCA disease (56%) both RVEF and LVEF decreased during exercise. Besides, in patients without RCA disease there was a significant linear relationship between the direction and magnitude of change from rest to exercise of LVEF and RVEF (r=0.69). (J.P.N.)

  18. International Atomic Energy Agency: activities in Malaysia

    Energy Technology Data Exchange (ETDEWEB)

    Hayati, Ainul [Nuclear Energy Unit, Bangi, Selangor (Malaysia)

    1994-12-31

    The two main IAEA activities participated by Malaysia - technical cooperation programme (TC) and regional cooperative agreement programme (RCA/IAEA AND IAEA/RCA/UNDP). This article highlighted some of the IAEA technical cooperation activities in Malaysia (i.e. Medicine, Agriculture, Industry, Strategic, Social Science), assistance, funding and contribution made by Malaysia to the IAEA since 1989.

  19. Anomalous origin of the right coronary artery with an interarterial course and intramural part

    Directory of Open Access Journals (Sweden)

    Simon Fuglsang

    2015-01-01

    Conclusion: In this report, we present some unique images of the RCAs course, which contribute to the understanding of this disease’s symptomatology. The patient successfully underwent surgery with Right Internal Mammary Artery to RCA (RIMA–RCA2 RIMA–RCA = right Internal mammary artery to right coronary artery. bypass with complete remission of all symptoms.

  20. International Atomic Energy Agency: activities in Malaysia

    International Nuclear Information System (INIS)

    Ainul Hayati

    1994-01-01

    The two main IAEA activities participated by Malaysia - technical cooperation programme (TC) and regional cooperative agreement programme (RCA/IAEA AND IAEA/RCA/UNDP). This article highlighted some of the IAEA technical cooperation activities in Malaysia (i.e. Medicine, Agriculture, Industry, Strategic, Social Science), assistance, funding and contribution made by Malaysia to the IAEA since 1989

  1. Systemic Vulnerabilities to Suicide among Veterans from the Iraq and Afghanistan Conflicts: Review of Case Reports from a National Veterans Affairs Database

    Science.gov (United States)

    Mills, Peter D.; Huber, Samuel J.; Watts, Bradley Vince; Bagian, James P.

    2011-01-01

    While suicide among recently returned veterans is of great concern, it is a relatively rare occurrence within individual hospitals and clinics. Root cause analysis (RCA) generates a detailed case report that can be used to identify system-based vulnerabilities following an adverse event. Review of a national database of RCA reports may identify…

  2. Root cause analysis of critical events in neurosurgery, New South Wales.

    Science.gov (United States)

    Perotti, Vanessa; Sheridan, Mark M P

    2015-09-01

    Adverse events reportedly occur in 5% to 10% of health care episodes. Not all adverse events are the result of error; they may arise from systemic faults in the delivery of health care. Catastrophic events are not only physically devastating to patients, but they also attract medical liability and increase health care costs. Root cause analysis (RCA) has become a key tool for health care services to understand those adverse events. This study is a review of all the RCA case reports involving neurosurgical patients in New South Wales between 2008 and 2013. The case reports and data were obtained from the Clinical Excellence Commission database. The data was then categorized by the root causes identified and the recommendations suggested by the RCA committees. Thirty-two case reports were identified in the RCA database. Breaches in policy account for the majority of root causes identified, for example, delays in transfer of patients or wrong-site surgery, which always involved poor adherence to correct patient and site identification procedures. The RCA committees' recommendations included education for staff, and improvements in rostering and procedural guidelines. RCAs have improved the patient safety profile; however, the RCA committees have no power to enforce any recommendation or ensure compliance. A single RCA may provide little learning beyond the unit and staff involved. However, through aggregation of RCA data and dissemination strategies, health care workers can learn from adverse events and prevent future events from occurring. © 2015 Royal Australasian College of Surgeons.

  3. Training health care professionals in root cause analysis: a cross-sectional study of post-training experiences, benefits and attitudes.

    Science.gov (United States)

    Bowie, Paul; Skinner, Joe; de Wet, Carl

    2013-02-07

    Root cause analysis (RCA) originated in the manufacturing engineering sector but has been adapted for routine use in healthcare to investigate patient safety incidents and facilitate organizational learning. Despite the limitations of the RCA evidence base, healthcare authorities and decision makers in NHS Scotland - similar to those internationally - have invested heavily in developing training programmes to build local capacity and capability, and this is a cornerstone of many organizational policies for investigating safety-critical issues. However, to our knowledge there has been no systematic attempt to follow-up and evaluate post-training experiences of RCA-trained staff in Scotland. Given the significant investment in people, time and funding we aimed to capture and learn from the reported experiences, benefits and attitudes of RCA-trained staff and the perceived impact on healthcare systems and safety. We adapted a questionnaire used in a published Australian research study to undertake a cross sectional online survey of health care professionals (e.g. nursing & midwifery, medical doctors and pharmacists) formally trained in RCA by a single territorial health board region in NHS Scotland. A total of 228/469 of invited staff completed the survey (48%). A majority of respondents had yet to participate in a post-training RCA investigation (n=127, 55.7%). Of RCA-experience staff, 71 had assumed a lead investigator role (70.3%) on one or more occasions. A clear majority indicated that their improvement recommendations were generally or partly implemented (82%). The top three barriers to RCA success were cited as: lack of time (54.6%), unwilling colleagues (34%) and inter-professional differences (31%). Differences in agreement levels between RCA-experienced and inexperienced respondents were noted on whether a follow-up session would be beneficial after conducting RCA (65.3% v 39.4%) and if peer feedback on RCA reports would be of educational value (83.2% v 37

  4. Echocardiographic and hemodynamic determinants of right coronary artery flow reserve and phasic flow pattern in advanced non-ischemic cardiomyopathy

    Directory of Open Access Journals (Sweden)

    Mady Charles

    2007-09-01

    Full Text Available Abstract Background In patients with advanced non-ischemic cardiomyopathy (NIC, right-sided cardiac disturbances has prognostic implications. Right coronary artery (RCA flow pattern and flow reserve (CFR are not well known in this setting. The purpose of this study was to assess, in human advanced NIC, the RCA phasic flow pattern and CFR, also under right-sided cardiac disturbances, and compare with left coronary circulation. As well as to investigate any correlation between the cardiac structural, mechanical and hemodynamic parameters with RCA phasic flow pattern or CFR. Methods Twenty four patients with dilated severe NIC were evaluated non-invasively, even by echocardiography, and also by cardiac catheterization, inclusive with Swan-Ganz catheter. Intracoronary Doppler (Flowire data was obtained in RCA and left anterior descendent coronary artery (LAD before and after adenosine. Resting RCA phasic pattern (diastolic/systolic was compared between subgroups with and without pulmonary hypertension, and with and without right ventricular (RV dysfunction; and also with LAD. RCA-CFR was compared with LAD, as well as in those subgroups. Pearson's correlation analysis was accomplished among echocardiographic (including LV fractional shortening, mass index, end systolic wall stress more hemodynamic parameters with RCA phasic flow pattern or RCA-CFR. Results LV fractional shortening and end diastolic diameter were 15.3 ± 3.5 % and 69.4 ± 12.2 mm. Resting RCA phasic pattern had no difference comparing subgroups with vs. without pulmonary hypertension (1.45 vs. 1.29, p = NS either with vs. without RV dysfunction (1.47 vs. 1.23, p = NS; RCA vs. LAD was 1.35 vs. 2.85 (p Conclusion In patients with chronic advanced NIC, RCA phasic flow pattern has a mild diastolic predominance, less marked than in LAD, with no effects from pulmonary artery hypertension or RV dysfunction. There is no significant correlation between any cardiac mechanical-structural or

  5. Two forms of acid alpha-D-mannosidase in monkey brain: evidence for the co-existence of high mannose and complex oligosaccharides in one form.

    Science.gov (United States)

    Mathur, R; Alvares, K; Balasubramanian, A S

    1984-09-28

    Lysosomal alpha-D-mannosidase of monkey brain existed in two forms. One form of mannosidase was bound to the Ricinus communis agglutinin120 (RCA1)-Sepharose and could be specifically eluted with lactose. The other form did not bind to the RCA1-Sepharose. Both forms of mannosidase could bind to a similar extent to the immobilized brain lysosomal receptor protein. Both the forms were purified to apparent homogeneity. Neutral sugar analysis by GLC showed the presence of glucose, mannose and galactose in the RCA1-Sepharose bindable mannosidase and glucose and mannose in the non-bindable mannosidase. Several other brain lysosomal hydrolases did not bind to the RCA1-Sepharose. The results suggested the existence of only high mannose oligosaccharides in the RCA1 non-bindable mannosidase and both high mannose and complex oligosaccharides in the bindable mannosidase.

  6. Controlled Microwave Heating Accelerates Rolling Circle Amplification.

    Science.gov (United States)

    Yoshimura, Takeo; Suzuki, Takamasa; Mineki, Shigeru; Ohuchi, Shokichi

    2015-01-01

    Rolling circle amplification (RCA) generates single-stranded DNAs or RNA, and the diverse applications of this isothermal technique range from the sensitive detection of nucleic acids to analysis of single nucleotide polymorphisms. Microwave chemistry is widely applied to increase reaction rate as well as product yield and purity. The objectives of the present research were to apply microwave heating to RCA and indicate factors that contribute to the microwave selective heating effect. The microwave reaction temperature was strictly controlled using a microwave applicator optimized for enzymatic-scale reactions. Here, we showed that microwave-assisted RCA reactions catalyzed by either of the four thermostable DNA polymerases were accelerated over 4-folds compared with conventional RCA. Furthermore, the temperatures of the individual buffer components were specifically influenced by microwave heating. We concluded that microwave heating accelerated isothermal RCA of DNA because of the differential heating mechanisms of microwaves on the temperatures of reaction components, although the overall reaction temperatures were the same.

  7. Developing a tool for assessing competency in root cause analysis.

    Science.gov (United States)

    Gupta, Priyanka; Varkey, Prathibha

    2009-01-01

    Root cause analysis (RCA) is a tool for identifying the key cause(s) contributing to a sentinel event or near miss. Although training in RCA is gaining popularity in medical education, there is no published literature on valid or reliable methods for assessing competency in the same. A tool for assessing competency in RCA was pilot tested as part of an eight-station Objective Structured Clinical Examination that was conducted at the completion of a three-week quality improvement (QI) curriculum for the Mayo Clinic Preventive Medicine and Endocrinology fellowship programs. As part of the curriculum, fellows completed a QI project to enhance physician communication of the diagnosis and treatment plan at the end of a patient visit. They had a didactic session on RCA, followed by process mapping of the information flow at the project clinic, after which fellows conducted an actual RCA using the Ishikawa fishbone diagram. For the RCA competency assessment, fellows performed an RCA regarding a scenario describing an adverse medication event and provided possible solutions to prevent such errors in the future. All faculty strongly agreed or agreed that they were able to accurately assess competency in RCA using the tool. Interrater reliability for the global competency rating and checklist scoring were 0.96 and 0.85, respectively. Internal consistency (Cronbach's alpha) was 0.76. Six of eight of the fellows found the difficulty level of the test to be optimal. Assessment methods must accompany education programs to ensure that graduates are competent in QI methodologies and are able to apply them effectively in the workplace. The RCA assessment tool was found to be a valid, reliable, feasible, and acceptable method for assessing competency in RCA. Further research is needed to examine its predictive validity and generalizability.

  8. Functional analysis of the rice rubisco activase promoter in transgenic Arabidopsis

    Energy Technology Data Exchange (ETDEWEB)

    Yang, Zhipan; Lu, Qingtao; Wen, Xiaogang [Key Laboratory of Photobiology, Institute of Botany, Chinese Academy of Sciences, Beijing 100093 (China); Chen, Fan [Key Laboratory of Molecular and Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100080 (China); Lu, Congming, E-mail: lucm@ibcas.ac.cn [Key Laboratory of Photobiology, Institute of Botany, Chinese Academy of Sciences, Beijing 100093 (China)

    2012-02-17

    Highlights: Black-Right-Pointing-Pointer Rice rubisco activase promoter was analyzed in transgenic Arabidopsis system. Black-Right-Pointing-Pointer Region conferring tissue specific and light inducible expression of Rca was identified. Black-Right-Pointing-Pointer -58 to +43 bp region mediates tissue-specific expression of rice Rca. Black-Right-Pointing-Pointer Light inducible expression of rice Rca is mediated by -297 to -58 bp region. Black-Right-Pointing-Pointer Rice nuclear proteins bind specifically with the light inducible region. -- Abstract: To gain a better understanding of the regulatory mechanism of the rice rubisco activase (Rca) gene, variants of the Rca gene promoter (one full-length and four deletion mutants) fused to the coding region of the bacterial reporter gene {beta}-glucuronidase (GUS) were introduced into Arabidopsis via Agrobacterium-mediated transformation. Our results show that a 340 bp fragment spanning from -297 to +43 bp relative to the transcription initiation site is enough to promote tissue-specific and light-inducible expression of the rice Rca gene as done by the full-length promoter (-1428 to +43 bp). Further deletion analysis indicated that the region conferring tissue-specificity of Rca expression is localized within a 105 bp fragment from -58 to +43 bp, while light-inducible expression of Rca is mediated by the region from -297 to -58 bp. Gel shift assays and competition experiments demonstrated that rice nuclear proteins bind specifically with the fragment conferring light responsiveness at more than one binding site. This implies that multiple cis-elements may be involved in light-induced expression of the rice Rca gene. These works provide a useful reference for understanding transcriptional regulation mechanism of the rice Rca gene, and lay a strong foundation for further detection of related cis-elements and trans-factors.

  9. Rubisco Activase Is Required for Optimal Photosynthesis in the Green Alga Chlamydomonas reinhardtii in a Low-CO2 Atmosphere1

    Science.gov (United States)

    Pollock, Steve V.; Colombo, Sergio L.; Prout, Davey L.; Godfrey, Ashley C.; Moroney, James V.

    2003-01-01

    This report describes a Chlamydomonas reinhardtii mutant that lacks Rubisco activase (Rca). Using the BleR (bleomycin resistance) gene as a positive selectable marker for nuclear transformation, an insertional mutagenesis screen was performed to select for cells that required a high-CO2 atmosphere for optimal growth. The DNA flanking the BleR insert of one of the high-CO2-requiring strains was cloned using thermal asymmetric interlaced-polymerase chain reaction and inverse polymerase chain reaction and sequenced. The flanking sequence matched the C. reinhardtii Rca cDNA sequence previously deposited in the National Center for Biotechnology Information database. The loss of a functional Rca in the strain was confirmed by the absence of Rca mRNA and protein. The open reading frame for Rca was cloned and expressed in pSL18, a C. reinhardtii expression vector conferring paromomycin resistance. This construct partially complemented the mutant phenotype, supporting the hypothesis that the loss of Rca was the reason the mutant grew poorly in a low-CO2 atmosphere. Sequencing of the C. reinhardtii Rca gene revealed that it contains 10 exons ranging in size from 18 to 470 bp. Low-CO2-grown rca1 cultures had a growth rate and maximum rate of photosynthesis 60% of wild-type cells. Results obtained from experiments on a cia5 rca1 double mutant also suggest that the CO2-concentrating mechanism partially compensates for the absence of an active Rca in the green alga C. reinhardtii. PMID:14605215

  10. Rubisco activase is required for optimal photosynthesis in the green alga Chlamydomonas reinhardtii in a low-CO(2) atmosphere.

    Science.gov (United States)

    Pollock, Steve V; Colombo, Sergio L; Prout, Davey L; Godfrey, Ashley C; Moroney, James V

    2003-12-01

    This report describes a Chlamydomonas reinhardtii mutant that lacks Rubisco activase (Rca). Using the BleR (bleomycin resistance) gene as a positive selectable marker for nuclear transformation, an insertional mutagenesis screen was performed to select for cells that required a high-CO2 atmosphere for optimal growth. The DNA flanking the BleR insert of one of the high-CO2-requiring strains was cloned using thermal asymmetric interlaced-polymerase chain reaction and inverse polymerase chain reaction and sequenced. The flanking sequence matched the C. reinhardtii Rca cDNA sequence previously deposited in the National Center for Biotechnology Information database. The loss of a functional Rca in the strain was confirmed by the absence of Rca mRNA and protein. The open reading frame for Rca was cloned and expressed in pSL18, a C. reinhardtii expression vector conferring paromomycin resistance. This construct partially complemented the mutant phenotype, supporting the hypothesis that the loss of Rca was the reason the mutant grew poorly in a low-CO2 atmosphere. Sequencing of the C. reinhardtii Rca gene revealed that it contains 10 exons ranging in size from 18 to 470 bp. Low-CO2-grown rca1 cultures had a growth rate and maximum rate of photosynthesis 60% of wild-type cells. Results obtained from experiments on a cia5 rca1 double mutant also suggest that the CO2-concentrating mechanism partially compensates for the absence of an active Rca in the green alga C. reinhardtii.

  11. Functional analysis of the rice rubisco activase promoter in transgenic Arabidopsis

    International Nuclear Information System (INIS)

    Yang, Zhipan; Lu, Qingtao; Wen, Xiaogang; Chen, Fan; Lu, Congming

    2012-01-01

    Highlights: ► Rice rubisco activase promoter was analyzed in transgenic Arabidopsis system. ► Region conferring tissue specific and light inducible expression of Rca was identified. ► −58 to +43 bp region mediates tissue-specific expression of rice Rca. ► Light inducible expression of rice Rca is mediated by −297 to −58 bp region. ► Rice nuclear proteins bind specifically with the light inducible region. -- Abstract: To gain a better understanding of the regulatory mechanism of the rice rubisco activase (Rca) gene, variants of the Rca gene promoter (one full-length and four deletion mutants) fused to the coding region of the bacterial reporter gene β-glucuronidase (GUS) were introduced into Arabidopsis via Agrobacterium-mediated transformation. Our results show that a 340 bp fragment spanning from −297 to +43 bp relative to the transcription initiation site is enough to promote tissue-specific and light-inducible expression of the rice Rca gene as done by the full-length promoter (−1428 to +43 bp). Further deletion analysis indicated that the region conferring tissue-specificity of Rca expression is localized within a 105 bp fragment from −58 to +43 bp, while light-inducible expression of Rca is mediated by the region from −297 to −58 bp. Gel shift assays and competition experiments demonstrated that rice nuclear proteins bind specifically with the fragment conferring light responsiveness at more than one binding site. This implies that multiple cis-elements may be involved in light-induced expression of the rice Rca gene. These works provide a useful reference for understanding transcriptional regulation mechanism of the rice Rca gene, and lay a strong foundation for further detection of related cis-elements and trans-factors.

  12. Comparison of cost determination of both resource consumption accounting and time-driven activity-based costing systems in a healthcare setting.

    Science.gov (United States)

    Özyapıcı, Hasan; Tanış, Veyis Naci

    2017-05-01

    Objective The aim of the present study was to explore the differences between resource consumption accounting (RCA) and time-driven activity-based costing (TDABC) systems in determining the costs of services of a healthcare setting. Methods A case study was conducted to calculate the unit costs of open and laparoscopic gall bladder surgeries using TDABC and RCA. Results The RCA system assigns a higher cost both to open and laparoscopic gall bladder surgeries than TDABC. The total cost of unused capacity under the TDABC system is also double that in RCA. Conclusion Unlike TDABC, RCA calculates lower costs for unused capacities but higher costs for products or services in a healthcare setting in which fixed costs make up a high proportion of total costs. What is known about the topic? TDABC is a revision of the activity-based costing (ABC) system. RCA is also a new costing system that includes both the theoretical advantages of ABC and the practical advantages of German costing. However, little is known about the differences arising from application of TDABC and RCA. What does this paper add? There is no study comparing both TDABC and RCA in a single case study based on a real-world healthcare setting. Thus, the present study fills this gap in the literature and it is unique in the sense that it is the first case study comparing TDABC and RCA for open and laparoscopic gall bladder surgeries in a healthcare setting. What are the implications for practitioners? This study provides several interesting results for managers and cost accounting researchers. Thus, it will contribute to the spread of RCA studies in healthcare settings. It will also help the implementers of TDABC to revise data concerning the cost of unused capacity. In addition, by separating costs into fixed and variable, the paper will help managers to create a blended (combined) system that can improve both short- and long-term decisions.

  13. Browse Title Index

    African Journals Online (AJOL)

    Items 451 - 500 of 789 ... Vol 38, No 1 (2015), On the inertia groups of the maximal subgroup 27:Sp6(2) in Aut(Fi22), Abstract. R.L. Fray, A.L. Prins. Vol 32, No 1 (2009), On the interlacing of zeros of linear combinations of Jacobi polynomials from different sequences, Abstract. Kathy Driver, Kerstin Jordaan, Norbert Mbuyi.

  14. Making the Most of Presidential Transitions

    Science.gov (United States)

    Marchese, Theodore J.

    2012-01-01

    The time between a president's resignation and the next president's assumption of office--often a 12-to-18 month period--can be crucial for an institution. Between the winding down of an existing presidency and the successful launch of the next, there are all too many opportunities for lost momentum, frayed relationships, key departures, and…

  15. KI~I)ERS I~ ~ILITERE VERI3A~1)

    African Journals Online (AJOL)

    dat hy te oud vir trompetblaser geword het. Hy kwalifiseer as Gesondheidsinspekteur en attesteer op 2 Junie 1944 weer by die Suid-. Afrikaanse Weermag om as Vrywilliger in. Wereldoorlog 1/ diens te doen. Hy word op. 17 Mei 1946 met die rang van sersant gede- mobiliseer. Op 70-jarige leeftyd tree Fray as Hoofgesond-.

  16. Poverty, Inequality and the Future of Social Policy: Western States in the New World Order.

    Science.gov (United States)

    McFate, Katherine, Ed.; Lawson, Roger, Ed.; Wilson, William Julius, Ed.

    This book analyzes forces fraying the social fabric of many countries, and the reasons why some Western countries have been more successful than others in addressing these trends. Part 1, "Poverty, Income Inequality, and Labor Market Insecurity: A Comparative Perspective," includes (1) "Markets and States: Poverty Trends and…

  17. Beyond the "Ivory Tower": Restoring the Balance of Private and Public Purposes of General Education

    Science.gov (United States)

    Cantor, Nancy; Englot, Peter

    2013-01-01

    We in higher education have allowed the balance of the private and public purposes of liberal education to become skewed in our angst over fully embracing a central role in restoring prosperity and preparing our increasingly diverse population for the evolving responsibility of mending our fraying democracy. As we consider how best to reshape…

  18. Nuclear targets, recoil ion catchers and reaction chambers

    NARCIS (Netherlands)

    Dionisio, JS; Vieu, C; Schuck, C; Collatz, R; Meunier, R; Ledu, D; Folger, H; Lafoux, A; Lagrange, JM; Pautrat, M; Waast, B; Phillips, WR; Blunt, D; Durell, JL; Varley, BJ; Dagnall, PG; Dorning, SJ; JONES, MA; Smith, AG; Bacelar, JCS; Rzaca-Urban, T; Amzal, N; Meliani, Z; Vanhorenbeeck, J; Passoja, A; Urban, W

    1998-01-01

    The main features of nuclear targets, recoil ion catchers and reaction chambers used in nuclear spectroscopic investigations involving in-beam multi-e-gamma spectrometers are discussed. The relative importance of the F-ray background due to the accelerated ion-target and the recoil-ion-target

  19. The Myth of Rational Objectivity and Leadership: The Realities of a Hospital Merger from a CEO's Perspective

    Science.gov (United States)

    Tobin, John H.

    2009-01-01

    Executive power and status depends on others' belief in the executive's capacity for control via rational decision-making, "by the numbers" and above the fray of day to day minutia. By exploring his own experience in the complex social dynamics of a long, complicated merger process--characterised by misunderstanding, incomplete…

  20. A Sociobiological Analysis Of Resource Control Issues | Nnadi ...

    African Journals Online (AJOL)

    Adopting the stand point that humans are part of the animal kingdom, the sociobiological phenomena of metamorphosis, aggression and territoriality are introduced into the fray. They are then juxtaposed to the issue of resource control and applied to improve understanding and, hopefully, management of the former.

  1. Enhancing the competitiveness of an SMME in the automotive industry through the introduction of laser based manufacturing. A case study

    CSIR Research Space (South Africa)

    Burger, HP

    2006-01-01

    Full Text Available to synthetic fibre the cut is produced by melting the individual fibres resulting in a semi sealed cut edge that is totally free of fraying and lint. This paper illustrates how the introduction of laser cutting into the manufacturing process not only solved...

  2. Burns

    Science.gov (United States)

    ... putting a child in the bathtub. Cover unused electric outlets with safety caps, and replace damaged, frayed or brittle electrical cords. Keep fire extinguishers on every floor of your house, especially in the kitchen, and know how to use them. Do not ...

  3. Textural parameters distribution in sediments surface of the Uruguay river background between km 221 and 254

    International Nuclear Information System (INIS)

    Capeluto, W.; Campos, T. de los

    2010-01-01

    The aim of this paper is to analyze the distribution of textural statistical parameters and spatial variation in the morphology of the sediment areas. The geology of the area comprises alluvial and alluvial deposits of variable thicknesses overlying deposits of Fray Bent os, Salto and Guichon formations that occasionally emerge in the river bed

  4. Spanish Comics as Genre

    Science.gov (United States)

    Kiely, Kristin

    2018-01-01

    Since the beginning of literary time, genre has been an issue for critics and scholars. Comics and graphic novels have stepped into the fray in recent decades causing even more confusion. This is even more evident in Spain where the publishers are foolhardy men and women simply out to make money and who are too deeply embedded in their bourgeois…

  5. Shadows at Europe's heart

    Index Scriptorium Estoniae

    2006-01-01

    Ülevaade Kesk- ja Ida-Euroopa riikide sisepoliitilistest konfliktidest, ebakompetentsuse ning korruptsiooni ilmingutest valitsustes. Toomas Hendrik Ilves kui positiivne näide Brüsselist kodumaale naasnud poliitikust. Vt. ka lk. 13-14: Europe's fraying fringe

  6. Retóricas del viaje a España, 1800-1900

    Directory of Open Access Journals (Sweden)

    Beatriz Colombi

    2014-06-01

    Full Text Available Partiendo de una reflexión crítica en torno a la literatura de viajes, se analizan los textos de Fray Servando, Sarmiento, Rubén Darío y Alfonso Reyes, para observar en ellos las relaciones que se establecen entre el viajero y, en este caso, España (expectativas, representaciones, descubrimientos.

  7. Simultaneous localization of an hepatic binding protein specific for galactose and of galactose-containing receptors on rat hepatocytes.

    Science.gov (United States)

    Horisberger, M; VonLanthen, M

    1978-11-01

    The hepatic binding protein, specific for galactose-terminated glycoproteins (asialoglycoproteins) and the receptors for the Ricinus communis lectin, specific for galactose residues (RCA1), were simultaneously localized on isolated rat hepatocytes by the gold method. The marker for the binding protein was prepared from gold granules (5 nm in diam.) labeled with ceruloplasmin and desialylated. The marker specific for galactose-containing receptors consisted of granules (17 nm in diameter) labeled with RCA1. It was established that both markers did not interact. Hepatocytes (fresh or briefly fixed with glutaraldehyde) were successively incubated with the asialoceruloplasmin and the RCA1 marker. Examination of thin sections by electron microscopy indicated that the binding protein and the RCA1 receptors were often in the proximity of each other on the plasmamembrane. Using the same technique, wheat germ agglutinin (WGA) receptors were generally found on area of the plasmamembrane poorly marked by the RCA1 gold marker. The binding of asialoceruloplasmin gold markers was studied as a function of the size of the granules. It became insignificant when the size was above 17 nm. Previous results have shown that the binding of RCA1 is low when the marker reaches 50 nm in size while WGA markers up to 75 nm are well bound by hepatocytes. It is therefore hypothesized that the binding protein and RCA1 receptors are located between glycoprotein brushes of increasing spacing while part or all of the WGA receptors are located at the periphery of the brushes.

  8. Enhancement of properties of recycled coarse aggregate concrete using bacteria

    Science.gov (United States)

    Sahoo; Arakha; Sarkar; P; Jha

    2016-01-01

    Due to rapid construction, necessity for raw materials of concrete, especially coarse aggregate, tends to increase the danger of early exhaustion of the natural resources. An alternative source of raw materials would perhaps delay the advent of this early exhaustion. Recycled coarse aggregate (RCA) plays a great role as an alternative raw material that can replace the natural coarse aggregate (NCA) for concrete. Previous studies show that the properties of RCA concrete are inferior in quality compared to NCA concrete. This article attempts to study the improvement of properties of RCA concrete with the addition of bacteria named as Bacillus subtilis. The experimental investigation was carried out to evaluate the improvement of the compressive strength, capillary water absorption, and drying shrinkage of RCA concrete incorporating bacteria. The compressive strength of RCA concrete is found to be increased by about 20% when the cell concentration of B. subtilis is 106 cells/ml. The capillary water absorption as well as drying shrinkage of RCA are reduced when bacteria is incorporated. The improvement of RCA concrete is confirmed to be due to the calcium carbonate precipitation as observed from the microstructure studies carried out on it such as EDX, SEM, and XRD.

  9. Mechanism of Enzyme Repair by the AAA+ Chaperone Rubisco Activase.

    Science.gov (United States)

    Bhat, Javaid Y; Miličić, Goran; Thieulin-Pardo, Gabriel; Bracher, Andreas; Maxwell, Andrew; Ciniawsky, Susanne; Mueller-Cajar, Oliver; Engen, John R; Hartl, F Ulrich; Wendler, Petra; Hayer-Hartl, Manajit

    2017-09-07

    How AAA+ chaperones conformationally remodel specific target proteins in an ATP-dependent manner is not well understood. Here, we investigated the mechanism of the AAA+ protein Rubisco activase (Rca) in metabolic repair of the photosynthetic enzyme Rubisco, a complex of eight large (RbcL) and eight small (RbcS) subunits containing eight catalytic sites. Rubisco is prone to inhibition by tight-binding sugar phosphates, whose removal is catalyzed by Rca. We engineered a stable Rca hexamer ring and analyzed its functional interaction with Rubisco. Hydrogen/deuterium exchange and chemical crosslinking showed that Rca structurally destabilizes elements of the Rubisco active site with remarkable selectivity. Cryo-electron microscopy revealed that Rca docks onto Rubisco over one active site at a time, positioning the C-terminal strand of RbcL, which stabilizes the catalytic center, for access to the Rca hexamer pore. The pulling force of Rca is fine-tuned to avoid global destabilization and allow for precise enzyme repair. Copyright © 2017 Elsevier Inc. All rights reserved.

  10. Rachycentron canadum (cobia) lectin promoted mitogenic response in mice BALB/c splenocytes.

    Science.gov (United States)

    Coriolano, M C; de Melo, C M L; Santos, A J G; Pereira, V R A; Coelho, L C B B

    2012-12-01

    The mitogenic lectins are invaluable tools to study the biochemical changes associated with lymphocyte activation and proliferation of various immune cells. Rachycentron canadum lectin (RcaL) was detected and purified from serum of cobia fish. The aim of this study was to evaluate the proliferative response and cytokine production in splenocytes of mice in vitro stimulated with RcaL lectin; Canavalia ensiformis lectin (Con A) was used as positive control. A high proliferation index was induced by RcaL in relation to control cells. Furthermore, RcaL induced higher IL-2 and IL-6 production in relation to control. The cell viability was 90% in splenocytes treated with RcaL lectin, but RcaL promoted significant late apoptosis after 24 and 48 h in relation to control. RcaL induced proliferative responses suggesting that this lectin can be used as a mitogenic agent in immunostimulatory assays. © 2012 The Authors. Scandinavian Journal of Immunology © 2012 Blackwell Publishing Ltd.

  11. Facility design to apply cover material over radioactive residue in storage silos

    International Nuclear Information System (INIS)

    Fekete, L.J.; Emerson, R.J. Jr.; Heckendorn, L.A.

    1991-01-01

    This paper discusses the BentoGrout application system designed by Parsons under contract to the US Department of Energy (DOE) for the Environmental Remedial Action (ERA) Project, Fernald Environmental Management Project (FEMP) Fernald, Ohio, as cleaned by the K-65 removal action work plan prepared by Theta Technologies, Inc. and Westinghouse Environmental Management Company of Ohio (WEMCO) with the objectives to reduce radon emissions from the silos. The paper discusses support activities undertaken to develop the design basis and design criteria for the K-65 Silos BentoGrout Covering System. The development and execution of an application demonstration program is described with presentation of the results. Also addressed is the design of the full-scale application system and the philosophy of operational control. The instrumentation and monitoring subsystems are illustrated on system schematics. The paper concludes with an evaluation of the above activities in achieving the purpose and objectives set forth in the Removal Action Work Plan

  12. CONSIDERAÇÕES ACERCA DA FICIONALIDADE E DA DIMENSÃO ARGUMENTATIVA EM “DOM CASMURRO”

    Directory of Open Access Journals (Sweden)

    Cristia Rodrigues Miranda

    2013-12-01

    Full Text Available This study aims to analyze, from the rhetorical perspective discourse discursive and argumentative present in Don Casmurro. To do so, left with the hypothesis that the narrative discourse of Bento, character-narrador, suggests a question that crystallized at the reception and points to the question about thesis: “Capitu cheated or not Bento?” To analyze these effects were useful in Mendes (2011 and (2004, studies on the fictionally. Perelman and Olbrechts-Tyteca (2005, Amossy (2011 and Aristotle (2008 helped us to analyze the size argumentative and rhetorical categorical supposedly present in the work. As the result the analysis pointed to an unfolding and dialogism in rethorical that turns accuser charged, ie, narrator and narrate defendand in court. All this narrative game would only be possible through the contract ficcional and argumentative dimension language.

  13. Two rubisco activase genes from ipomoea batatas have different roles in photosynthesis of arabidopsis

    International Nuclear Information System (INIS)

    Jiang, Y.

    2014-01-01

    Rubisco activase (RCA) that functions as a molecular chaperone regulates the activity of the Calvin-Benson cycle via regulation of the Rubisco activity. In plants such as Arabidopsis thaliana, Spinacia oleracea, and Oryza sativa, there are two RCA isoforms from two mRNAs that are produced from alternative splicing of the transcribed pre-mRNA of a single RCA gene. However, this research reported that the transcripts of the two IbRCA isoforms in sweet potato (Ipomoea batatas) were transcribed from two different genes. To study the roles of these two IbRCA isoforms in photosynthesis, we inserted these two IbRCA genes into the genome of Arabidopsis with deletion of RCA gene (RCA), resulting in IbRCAs- and IbRCAl-expressing plants, respectively. Analysis of these transgenic Arabidopsis indicated that the IbRCAs-expressing plants were similar to wild-type plants under ambient CO/sub 2/ concentration and 22 degree C conditions, suggesting that expression of IbRCAs gene was sufficient for functional complementation of RCA plants under normal conditions. However, IbRCAs-expressing plants were more susceptible to moderate heat stress (26 degree C) compared to wild-type plants. In contrast, although the IbRCAl-expressing plants had to grow normally in high CO/sub 2/ concentration conditions, there were almost no differences in growth and photosynthesis between normally grown and heat-treated plants, implying that IbRCAl-expressing plants had a better heat-resistance than IbRCAs-expressing plants. (author)

  14. Evaluation of right coronary anomalous origin with mulpi-slice spiral CT

    International Nuclear Information System (INIS)

    Shi Heshui; Han Ping; Kong Xiangquan; Feng Hansheng; Brambs, H.-J.; Hoffmann, M.H.K.

    2006-01-01

    Objective: To evaluate the role of 16-slice spiral computed tomography angiography (MSCTA) to identify the anomalous origin and anatomic course of the right coronary artery (RCA) with conventional X-ray coronary angiography (CAG) serving as standard of reference. Methods: MSCTA data in 8 patients with anomalous RCA were retrospectively analyzed for the study, 7 of them had also undergone CAG examinations. MSCTA and CAG images were analyzed in blinded fashion for accuracy of anomalous artery origin and path detection. Results were compared in a secondary consensus evaluation. Virtual endoscopy (VE) was used to evaluate the orifice of the anomalous arteries and its relationship with the adjacent ostia of normal arteries. Multi-planar reconstruction (MPR), curved MPR, thin-slab maximum intensity projection (MIP), volume rendering (VR) or slab VR (cut-plane VR) were used to assess the aberrant path of the RCA and its relationship with the adjacent large vessels. At least two views of the RCA were analyzed on CAG. Results: The anomalous RCA for all 8 patients were correctly displayed on MSCTA. RCA originated from the left sinus of Valsalva in 6 patients, one RCA from the end of left main coronary artery, another RCA arose from the posterior sinus of Valsalva. The anomalous ostia showed no stenosis. All of them passed between the aortic root and the pulmonary artery. For 7 patients with CAG alone correct identification of the abnormality was achieved in only 71%. Conclusion: MSCTA was superior to show the anomalous orifice and path of the RCA, it should be considered as a prime non-invasive imaging tool for suspected coronary anomalies. (authors)

  15. Small group presentations for each session

    International Nuclear Information System (INIS)

    2011-01-01

    This section presents the results of the questionnaires with the recommendations from the 3 discussion groups. The questions approached are as follows: 1 - Discussion Group 1, 2 and 3 - Senior Management / Organizational Issues: Do Senior Managers understand the root cause analysis (RCA) process? Who in the organization is responsible for RCA? Are there regulatory requirements / influence? Does the culture of the organization affect the RCA process? Specific Recommendations. 2 - Discussion Group 1, 2 and 3 - Systematic Methodology / Tools: What are the challenges in using available analyses tools for identification of Human and Organisational Factors (HOF) in RCA? How do you 'handle' the perceived qualitative/subjective nature of HOF? Is the vocabulary used in RCA methodologies consistent? Will organizational issues be identified in analyses less intensive than RCA? Are you able to identify organizational issues from a single event? Is it difficult to make a clear link between RCA and CAs? What do you do if your scope expands? Recommendations. 3 - Discussion Group 1, 2 and 3 - Team Composition / Attributes: What are the challenges associated in team / individual competence? Is there management / HOF representation on the team? Does the level of the management sponsor affect the willingness of the organization to accept the HOF in RCA? Are RCA results presented to management? Who presents? Recommendations. 4 - Discussion Group 1, 2 and 3 - Learning: How many RCAs are done in a year? Is this sufficient? Could you identify organizational issues using an 'Apparent Cause Analysis' method? Are events with HOF issues trended in your organization? How do you know you have a learning organization? How can you measure the effectiveness of CAs?

  16. ANALISIS SISTEM PENETAPAN FRANCHISE FEE DAN ROYALTY FEE PADA FRANCHISE BRC

    Directory of Open Access Journals (Sweden)

    Walid Darmawan

    2016-02-01

    Full Text Available Pada saat ini bisnis franchise atau waralaba di indonesia, semakin menjamur dan banyak diminati oleh masyarakat untuk mencari peluang baru, dari mulai waralaba lokal seperti Ayam bakar Wong Solo, Es Teller 77, Burger Mr.Edam,Alfa Mart, Indomart dan lain-lain. Sampai waralaba mancanegarapun semakin banyak diminati seperti KFC, Mc.Donalds, Hoka-Hoka Bento, Starbuck Coffiee dan lain sebagainya.DOI: 10.15408/aiq.v2i1.2472

  17. London-type congestion tax with revenue-recycling

    OpenAIRE

    Yukihiro Kidokoro

    2005-01-01

    Road pricing in London attracts a great deal of interest. A challenging aspect of the London scheme is that congestion tax revenue is used to upgrade public transit networks. Although Parry and Bento (2001) show that the total social surplus would increase if congestion tax revenues are used to cut labor taxes, political difficulties exist in implementing revenue-recycling between congestion taxes and labor taxes. Given such political difficulties, the London scheme seems to be very attractiv...

  18. Brane-world cosmology and inflation

    Indian Academy of Sciences (India)

    A Lukas and D Skinner, J. High Energy Phys. 0109, 020 (2001). M C Bento, O Bertolami and A A Sen, Phys. Rev. D67, 063511 (2003). [8] J Garriga and M Sasaki, Phys. Rev. D62, 043523 (2000). [9] K Koyama and J Soda, Phys. Lett. B483, 432 (2000). [10] S Kanno, M Sasaki and J Soda, Prog. Theor. Phys. 109, 357 (2003).

  19. Analisis Sistem Penetapan Franchise Fee dan Royalty Fee pada Franchise Brc

    OpenAIRE

    Darmawan, Walid

    2010-01-01

    Pada saat ini bisnis franchise atau waralaba di indonesia, semakin menjamur dan banyak diminati oleh masyarakat untuk mencari peluang baru, dari mulai waralaba lokal seperti Ayam bakar Wong Solo, Es Teller 77, Burger Mr.Edam,Alfa Mart, Indomart dan lain-lain. Sampai waralaba mancanegarapun semakin banyak diminati seperti KFC, Mc.Donalds, Hoka-Hoka Bento, Starbuck Coffiee dan lain sebagainya.DOI: 10.15408/aiq.v2i1.2472

  20. Snake population venomics and antivenomics of Bothrops atrox: Paedomorphism along its transamazonian dispersal and implications of geographic venom variability on snakebite management

    OpenAIRE

    Calvete, Juan J.; Sanz, Libia; Pérez, Alicia; Borges, Adolfo; Vargas, Alba M.; Lomonte, Bruno; Angulo, Yamileth; Gutiérrez, José María; Chalkidis, Hipócrates M.; Mourão, Rosa H.V.; Furtado, María de Fátima; Moura Da Silva, Ana M.

    2011-01-01

    We describe two geographically differentiated venom phenotypes across the wide distribution range of Bothrops atrox, from the Colombian Magdalena Medio Valley through Puerto Ayacucho and El Paují, in the Venezuelan States of Amazonas and Orinoquia, respectively, and São Bento in the Brazilian State of Maranhão. Colombian and Venezuelan venoms show an ontogenetic toxin profile phenotype whereas Brazilian venoms exhibit paedomorphic phenotypes. Venoms from each of the 16 localities sampled cont...

  1. Data on optimum recycle aggregate content in production of new structural concrete.

    Science.gov (United States)

    Paul, Suvash Chandra

    2017-12-01

    This data presented herein are the research summary of "mechanical behavior and durability performance of concrete containing recycled concrete aggregate" (Paul, 2011) [1]. The results reported in this article relate to an important parameter of optimum content of recycle concrete aggregate (RCA) in production of new concrete for both structural and non-structural applications. For the purpose of the research various types of physical, mechanical and durability tests are performed for concrete made with different percentages of RCA. Therefore, this data set can be a great help of the readers to understand the mechanism of RCA in relates to the concrete properties.

  2. A rare anomaly: Double right coronary artery

    Directory of Open Access Journals (Sweden)

    Dursun Çayan Akkoyun

    2013-01-01

    Full Text Available Coronary artery anomalies are rare anomalies. Theseare usually asymptomatic and are discovered incidentally.Double right coronary artery (RCA is a rare coronaryartery anomaly. Although there is controversy aboutidentification and classification of double RCA, it is oftena benign condition, but it can be complicated by atherosclerosisand can lead to serious conditions such asmyocardial infarction (MI and may be accompanied byother anomalies. In our case, double RCA were detectedin coronary angiography for acute anterior MI, and in thenext session successful percutaneous coronary interventionwas performed.Key words: Coronary anomaly, coronary angiography,coronary stenosis

  3. Simple engineering design for complex thermoelectric generators based on reduced current approach

    DEFF Research Database (Denmark)

    Wijesooriyage, Waruna Dissanayaka; Rezaniakolaei, Alireza; Rosendahl, Lasse

    2015-01-01

    Thermoelectric generators (TEGs) are niche candidate for the field of energy management as electrical generator devices. Generally, comprehensive and accurate design techniques for TEGs (thermoelectric generators), such as reduced current approach (RCA), are complex and time consuming processes....... This study develops a simple, comprehensive and accurate TEG designing technique based on RCA. The proposed method can predict the most efficient TEG architecture with more than 97% accuracy comparing to the RCA over wide range of possible temperature and zT for present TEG applications. Moreover...

  4. Benefits of aggregates surface modification in concrete production

    Science.gov (United States)

    Junak, J.; Sicakova, A.

    2017-10-01

    In our study, recycled concrete aggregates (RCA), which surfaces had been modified by geopolymer material based on coal fly ash, were used to produce the concrete samples. In these samples, fraction 4/8 mm was replaced by recycled concrete aggregate with a range of 100%. To modify the surface of RCA was “Solo” and “Triple stage” modification used. On these samples real density, total water absorption and compressive strength were examined after 28, 90, 180 and 365 days of hardening. The highest compressive strength 56.8 MPa, after 365 days hardening, reached sample which had improved RCA surface by “Triple stage mixing”.

  5. HV Switch Tube Development Program status report: April 28, 1978

    International Nuclear Information System (INIS)

    Winje, R.A.

    1978-01-01

    The HV Switch Tube Development Program encompassed development contracts to both Eimac (Division of Varian) and RCA. Both companies were required to develop a design for the tube and to build and test two tubes. The development program began in April, 1976. Currently, both companies have built tubes; Eimac has built one and RCA has built two. As initially built, both tubes exhibited unstable operation; however, RCA has implemented design changes which stabilized the tube operation. Eimac has a design modification which they believe will produce stable operation when the change is implemented. Both tubes have been tested to a limited degree and no other abnormal characteristics have been observed

  6. Visit by representatives from the Ministry of Science and Technology, Spain

    CERN Multimedia

    Maximilien Brice

    2002-01-01

    Photo 01: Jean-Luc Baldy, leader of CERN's civil engineering group (right), accompanies the visitors on a tour of excavation work in the large ATLAS cavern at Point 1: (left to right) Montserrat Capellas from the CERN Press Office, María José Jerez et María Requejo from the Spanish Ministry of Science and Technology, and Julio Oropesa from ETT division. Photo 02: (left to right) Montserrat Capellas, CERN guide Joao Bento, María José Jerez, María Requejo, and Julio Oropesa visit CERN's Antiproton Decelerator (AD) facility. Photo 03: (left to right) Montserrat Capella, María Requejo, Julio Oropesa, María José Jerez, and Joao Bento get a bird's eye view of the ATHENA experiment for the production of antihydrogen at the AD. Photo 04: Jean-Luc Baldy (right) explains surface civil engineering work at Point 1 to the visitors: (left to right) Julio Oropesa, María Requejo, María José Jerez, Joao Bento, and Montserrat Capella.

  7. ASPECTOS BIOLÓGICOS DE Holochilus sp., HOSPEDEIRO NATURAL DA ESQUISTOSSOMOSE

    Directory of Open Access Journals (Sweden)

    Maria Gabriela Sampaio Lira

    2016-01-01

    Full Text Available In the present study, we aimed to analyze the reproductive aspects (seasonal period and number of embryos and positivity for S. mansoni in rodent of Holochilus gender, in São Bento - MA. For this, monthly captures of up to 10 Holochilus sp. rodents were conducted, randomly for sex, taking notes of the seasonal period of São Bento in each month of capture. At the laboratory, rodents had feces analyzed for S. mansoni infection by Kato-Katz method. After the analysis, they were adequately anesthetized for obtaining full length, weight and sex determination. In females, an incision of the ventral portion of the body was carried out to verify the presence of embryos and to count them. Among the captured rodents, there was male dominance in almost all months and they tended to be heavier and had larger bodies than the females. The animals showed high reproductive potential. The positivity for S. mansoni and the reproduction of Holochilus sp. were greater in the rainy season of São Bento. As for the number of embryos, we observed that, in the rainy season, more males were found than female. In short, the intense reproductive activity, along the susceptibility to S. mansoni presented by rodents are factors that help to maintain and aggravate schistosomiasis in Baixada Maranhense.

  8. Organo-modified bentonites as new flame retardant fillers in epoxy resin nanocomposites

    Science.gov (United States)

    Benelli, Tiziana; D'Angelo, Emanuele; Mazzocchetti, Laura; Saraga, Federico; Sambri, Letizia; Franchini, Mauro Comes; Giorgini, Loris

    2016-05-01

    The present work deals with two organophilic bentonites, based on nitrogen-containing compounds: these organoclays were synthesized via an ion exchange process starting from pristine bentonite with 6-(4-butylphenyl)-1,3,5-triazine-2,4-diamine (BFTDA) and 11-amino-N-(pyridine-2yl)undecanamide (APUA) and then used for the production of epoxy-based flame retardant nanocomposites. The amount of organic modifier in the organoclays Bento-BFTDA and Bento-APUA was determined with a TGA analysis and is around 0.4mmol/g for both samples. The effect of the organoclays on a commercial epoxy resin nanocomposite's thermo-mechanical and flammability properties was investigated. Composites containing 3wt% and 5wt% of the nanofillers were prepared by solventless addition of each organoclay to the epoxy resin, followed by further addition of the hardener component. For the sake of comparison a similar nanocomposite with the plain unmodified bentonite was produced in similar condition. The nanocomposites's thermo-mechanical properties of all the produced samples were measured and they resulted slightly improved or practically unaffected. On the contrary, when the flame behaviour was assessed in the cone-calorimeter, an encouraging decrease of 17% in the peak heat released rate (pHRR) was obtained at 3wt% loading level with Bento-APUA. This is a promising result, assessing that the APUA modified organoclay might act as flame retardant.

  9. Review of "Echinococcus and Echinococcosis, Part A." edited by R. C. Andrew Thompson, Alan J. Lymbery and Peter Deplazes.

    Science.gov (United States)

    Ito, Akira

    2017-09-04

    Thompson RCA, Deplazes P, Lymbery AJ, Editors. Echinococcus and Echinococcosis, Part A. Volume 95, Advances in Parasitology 95. Academic Press; 2017. 525 pages, ISBN 978-0-12-8114711 (hardcover); 9780128114728 (eBook).

  10. Anomalous Coronary Artery From the Opposite Sinus (ACAOS): Technical Challenges During Percutaneous Coronary Intervention.

    Science.gov (United States)

    Sinha, Santosh Kumar; Razi, Mahmodula; Mahrotra, Anupam; Aggarwal, Puneet; Singh, Anupam; Rekwal, Lokendra; Tripathi, Sunil; Abhishekh, Nishant Kumar; Krishna, Vinay

    2018-04-01

    Anomalies of the coronary arteries are reported in 1-2% of patients among diagnostic angiogram. Ectopic origin of right coronary artery (RCA) from opposite sinus is one of the most common and they are mainly benign, but at times may be malignant. We report a case of a 69-year-old male who underwent early invasive percutaneous coronary intervention for non-ST-segment elevation myocardial infarction (NSTEMI) where RCA arising from left sinus at the root of left main artery was culprit and various technical challenges were encountered while intervening in form of cannulation to tracking of hardwares. RCA was cannulated with floating wire technique using hockey stick guide catheter and revascularized by deployment of 3.5 × 38 mm Promus Premier Everolimus eluting stent (Boston Scientific, USA). To the best of our knowledge, this is the first ever report of ectopic RCA being revascularized by using hockey stick catheter.

  11. Evaluation of waste concrete road materials for use in oyster aquaculture.

    Science.gov (United States)

    2013-02-01

    The primary objective of this study was to determine the suitability of recycled concrete : aggregate (RCA) from road projects as bottom conditioning material for on-bottom oyster : aquaculture in the Chesapeake Bay. The testing was designed to (1) e...

  12. Phase II evaluation of waste concrete road materials for use in oyster aquaculture - field test.

    Science.gov (United States)

    2015-02-01

    The overall objective of this study was to determine the suitability of recycled concrete aggregate : (RCA) from road projects as bottom conditioning material for on-bottom oyster aquaculture in the : Chesapeake Bay. During this Phase of the study, t...

  13. Concrete debris assessment for road construction activities : final report.

    Science.gov (United States)

    2016-08-01

    Two distinct but related issues of importance to FDOT were investigated: (1) the possible impact of : recycled concrete aggregate (RCA) used as road base on the subsurface environment and (2) the : management of concrete grinding residuals (CGR) resu...

  14. Concrete debris assessment for road construction activities : summary.

    Science.gov (United States)

    2016-09-01

    University of Florida researchers studied the possible : impact of recycled concrete aggregate (RCA) used in : roadway base layers on the acid/base balance of the : subsurface environment. They also examined a related : issue: management of concrete ...

  15. West Coast Rockfish Conservation Areas, 2015

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — These data delineate Rockfish Conservation Areas (RCA) off the West Coast of the United States for 2015. There are three types of areas closures depicted in this...

  16. Rare presentation of intralobar pulmonary sequestration associated with repeated episodes of ventricular tachycardia.

    Science.gov (United States)

    Rao, D Sheshagiri; Barik, Ramachandra

    2016-07-26

    Arterial supply of an intralobar pulmonary sequestration (IPS) from the coronary circulation is extremely rare. A significant coronary steal does not occur because of dual or triple sources of blood supply to sequestrated lung tissue. We present a 60-year-old woman who presented to us with repeated episodes of monomorphic ventricular tachycardia (VT) in last 3 mo. Radio frequency ablation was ineffective. On evaluation, she had right lower lobe IPS with dual arterial blood supply, i.e., right pulmonary artery and the systemic arterial supply from the right coronary artery (RCA). Stress myocardial perfusion scan revealed significant inducible ischemia in the RCA territory. Coronary angiogram revealed critical stenosis of proximal RCA just after the origin of the systemic artery supplying IPS. The critical stenosis in the RCA was stented. At 12 mo follow-up, she had no further episodes of VT or angina.

  17. Visualisation of lectin binding sites on the surface of human platelets using lectins adsorbed to gold granules.

    Science.gov (United States)

    Nurden, A T; Horisberger, M; Savariau, E; Caen, J P

    1980-10-15

    Washed human platelets have been incubated with the lectins WGA, ConA and RCA1, adsorbed to different-sized gold particles. Plasma membrane receptors for each lectin were then located by scanning and transmission electron microscopy.

  18. Expression of Ricinus communis receptors on epithelial cells in oral carcinomas and oral wounds.

    Science.gov (United States)

    Dabelsteen, E; Mackenzie, I C

    1978-12-01

    The histological distribution of receptors for Ricinus communis Fraction 1 (RCA1) in oral carcinomas and in oral epithelial cells during wound healing has been studied by use of fluorescein-tagged RCA1. Biopsies from 15 human oral carcinomas and adjacent normal mucosa showed RCA1 receptors at the cell membranes in the basal and spinous layer of the normal epithelium, whereas receptors could not be demonstrated in invading islands of the tumors. In healing oral wounds from eight humans and three monkeys, RCA1 receptors were demonstrated both in normal epithelium adjacent to the wounds and in the epithelial outgrowth from the wound margin. Titrations, however, showed that the epithelial outgrowth reacted more weakly than did the normal adjacent epithelium. These results support previous in vitro studies showing changes in carbohydrate composition of moving normal cells and of malignant cells, a finding that may be of interest in relation to formation of metastases.

  19. Linear reversible second-order cellular automata and their first-order matrix equivalents

    Science.gov (United States)

    Macfarlane, A. J.

    2004-11-01

    Linear or one-dimensional reversible second-order cellular automata, exemplified by three cases named as RCA1-3, are introduced. Displays of their evolution in discrete time steps, &{\\in}Z_2;) as for RCA1-3. MCA1-3 are tractable because it has been possible to generalize to them the heavy duty methods already well-developed for ordinary first-order cellular automata like those of Wolfram's Rules 90 and 150. While the automata MCA1-3 are thought to be of genuine interest in their own right, with untapped further mathematical potential, their treatment has been applied here to expediting derivation of a large body of general and explicit results for N(t) for RCA1-3. Amongst explicit results obtained are formulas also for each of RCA1-3 for the total weight of the configurations of the first &2^M; times, M =0, 1, 2,\\ldots.

  20. Coronary intervention in anomalous origin of the right coronary artery (ARCA from the left sinus of valsalva (LSOV: A single center experience

    Directory of Open Access Journals (Sweden)

    Kalaichelvan Uthayakumaran

    2014-07-01

    Conclusion: PCI of anomalous RCA origin from LSOV requires appropriate guide catheter selection according to the anatomy of origin for successful cannulation and to reduce the contrast usage and radiation exposure.

  1. Recycled concrete aggregate : field implementation at the Stan Musial Veterans Memorial Bridge.

    Science.gov (United States)

    2014-08-01

    The main objective of this research is to evaluate the feasibility of using RCA for concrete production in rigid pavement applications. : The experimental program was undertaken to investigate the performance of different concrete made with different...

  2. Comminution and sizing processes of concrete block waste as recycled aggregates.

    Science.gov (United States)

    Gomes, P C C; Ulsen, C; Pereira, F A; Quattrone, M; Angulo, S C

    2015-11-01

    Due to the environmental impact of construction and demolition waste (CDW), recycling is mandatory. It is also important that recycled concrete aggregates (RCA) are used in concrete to meet market demands. In the literature, the influence of RCAs on concrete has been investigated, but very limited studies have been conducted on how the origin of concrete waste and comminution processes influence RCA characteristics. This paper aims to investigate the influence of three different comminution and sizing processes (simple screening, crushing and grinding) on the composition, shape and porosity characteristics of RCA obtained from concrete block waste. Crushing and grinding implies a reduction of RCA porosity. However, due to the presence of coarse quartz rounded river pebbles in the original concrete block mixtures, the shape characteristics deteriorated. A large amount of powder (<0.15 mm) without detectable anhydrous cement was also generated. Copyright © 2015 Elsevier Ltd. All rights reserved.

  3. The mechanical properties of brick containing recycled concrete aggregate and polyethylene terephthalate waste as sand replacement

    Science.gov (United States)

    Sheikh Khalid, Faisal; Bazilah Azmi, Nurul; Natasya Mazenan, Puteri; Shahidan, Shahiron; Ali, Noorwirdawati

    2018-03-01

    This research focuses on the performance of composite sand cement brick containing recycle concrete aggregate and waste polyethylene terephthalate. This study aims to determine the mechanical properties such as compressive strength and water absorption of composite brick containing recycled concrete aggregate (RCA) and polyethylene terephthalate (PET) waste. The bricks specimens were prepared by using 100% natural sand, they were then replaced by RCA at 25%, 50% and 75% with proportions of PET consists of 0.5%, 1.0% and 1.5% by weight of natural sand. Based on the results of compressive strength, only RCA 25% with 0.5% PET achieve lower strength than normal bricks while others showed a high strength. However, all design mix reaches strength more than 7N/mm2 as expected. Besides that, the most favorable mix design that achieves high compressive strength is 75% of RCA with 0.5% PET.

  4. Durability assessment of recycled concrete aggregates for use in new concrete.

    Science.gov (United States)

    2012-06-01

    The primary goal of this research project was to investigate the long-term durability of concrete incorporating : recycled concrete aggregate (RCA) through accelerated laboratory testing. Overall it was found that modifications to : standard aggregat...

  5. 3-D Imaging using Row--Column-Addressed 2-D Arrays with a Diverging Lens

    DEFF Research Database (Denmark)

    Bouzari, Hamed; Engholm, Mathias; Stuart, Matthias Bo

    2016-01-01

    It has been shown that row–column-addressed (RCA) 2-D arrays can be an inexpensive alternative to fully addressed 2-D arrays. Generally imaging with an RCA 2-D array is limited to its forward-looking volume region. Constructing a double-curved RCA 2-D array or applying a diverging lens over......, is designed for imaging down to 14 cm at a volume rate of 88 Hz. The curvilinear imaging performance of a λ/2-pitch 3 MHz 62+62 RCA 2-D array is investigated as a function of depth, using a diverging lens with f-number of -1. The results of this study demonstrate that the proposed beamforming approach...

  6. Phase II evaluation of waste concrete road materials for use in oyster aquaculture - field test.

    Science.gov (United States)

    2014-11-01

    The overall objective of this study was to determine the suitability of recycled concrete : aggregate (RCA) from road projects as bottom conditioning material for on-bottom oyster : aquaculture in the Chesapeake Bay. During this Phase of the study, t...

  7. Steam-deformed Judkins-left guiding catheter with use of the GuideLiner catheter to deliver stents for anomalous right coronary artery

    Directory of Open Access Journals (Sweden)

    Toshiki Kuno

    2015-10-01

    Full Text Available Objective: Percutaneous coronary intervention for anomalous right coronary artery (RCA originating from the left coronary cusp is challenging because of our current inability to coaxially engage the guiding catheter. Methods: We report a case of an 88-year-old woman with non-ST segment elevation myocardial infarction, with an anomalous RCA origin. Using either the Judkins-Left catheter or Amplatz-Left catheter was difficult because of RCA ostium tortuosity. Thus, we used steam to deform the Judkins-Left catheter, but back-up support was insufficient to deliver the stent. Results: We used GuideLiner®, a novel pediatric catheter with rapid exchange/monorail systems, to enhance back-up support. Conclusions: We were able to successfully stent with both the deformed Judkins-Left guiding catheter and GuideLiner® for an anomalous RCA origin.

  8. Steam-deformed Judkins-left guiding catheter with use of the GuideLiner(®) catheter to deliver stents for anomalous right coronary artery.

    Science.gov (United States)

    Kuno, Toshiki; Fujisawa, Taishi; Yamazaki, Hiroyuki; Motoda, Hiroyuki; Kodaira, Masaki; Numasawa, Yohei

    2015-01-01

    Percutaneous coronary intervention for anomalous right coronary artery (RCA) originating from the left coronary cusp is challenging because of our current inability to coaxially engage the guiding catheter. We report a case of an 88-year-old woman with non-ST segment elevation myocardial infarction, with an anomalous RCA origin. Using either the Judkins-Left catheter or Amplatz-Left catheter was difficult because of RCA ostium tortuosity. Thus, we used steam to deform the Judkins-Left catheter, but back-up support was insufficient to deliver the stent. We used GuideLiner®, a novel pediatric catheter with rapid exchange/monorail systems, to enhance back-up support. We were able to successfully stent with both the deformed Judkins-Left guiding catheter and GuideLiner® for an anomalous RCA origin.

  9. Evaluation of recycled concrete as aggregate in new concrete pavements.

    Science.gov (United States)

    2014-04-01

    This study evaluated the use of recycled concrete as coarse aggregate in new concrete pavements. : Recycled concrete aggregate (RCA) produced from demolished pavements in three geographically dispersed locations in Washington state were used to perfo...

  10. 50 CFR 660.330 - Open access fishery-management measures.

    Science.gov (United States)

    2010-10-01

    ....S./Mexico border) is permitted within the nontrawl RCA with fixed gear only under the following... coordinates at §§ 660.398-.399: Thompson Seamount, President Jackson Seamount, Cordell Bank (50-fm (91-m...

  11. 50 CFR 660.383 - Open access fishery management measures.

    Science.gov (United States)

    2010-10-01

    .... south to the U.S./Mexico border) is permitted within the non-trawl RCA with fixed gear only under the..., President Jackson Seamount, Cordell Bank (50-fm (91-m) isobath), Harris Point, Richardson Rock, Scorpion...

  12. Next Generation Life Support (NGLS): Rapid Cycle Amine Swing Bed

    Data.gov (United States)

    National Aeronautics and Space Administration — The Rapid Cycle Amine (RCA) swingbed has been identified as a technology with high potential to meet the stringent requirements for the next generation spacesuit's...

  13. Evaluation of crushed concrete base strength.

    Science.gov (United States)

    2012-12-01

    This research project was conducted with two primary objectives, which include: 1) determine whether current Mississippi Department of Transportation (MDOT) requirements for recycled concrete aggregates (RCA) provide adequate materials for a roadway ...

  14. Furosemide-131I-hippuran renography after angiotensin-converting enzyme inhibition for the diagnosis of renovascular hypertension

    International Nuclear Information System (INIS)

    Erbsloeh-Moeller, B.Du.; Dumas, A.; Roth, D.; Sfakianakis, G.N.; Bourgoignie, J.J.

    1991-01-01

    We have previously demonstrated the greater sensitivity of 131I-hippuran renography than 99mTC-DTPA scintigraphy to diagnose renovascular hypertension (RVH). This study assesses the predictive diagnostic value of furosemide-131I-hippuran renography after angiotensin-converting enzyme (ACE) inhibition in patients with and without RVH. All patients were investigated at the University of Miami/Jackson Memorial Medical Center. Twenty-eight patients had RVH and 22 did not. Twenty-eight patients had normal or minimally decreased renal function and 22 had renal insufficiency. Renography was performed 60 minutes after oral administration of 50 mg captopril or 10 minutes after intravenous injection of 40 micrograms/kg enalaprilat. Forty milligrams of furosemide were administered intravenously 2 minutes after injection of 131I-hippuran. The residual cortical activity (RCA) of 131I-hippuran was measured at 20 minutes. RVH was unlikely when RCA after ACE inhibition was less than 30% of peak cortical activity. Conversely, RVH was present when 131I-hippuran cortical activity steadily increased throughout the test to reach 100% at 20 minutes. In azotemic patients with RCA between 31% and 100%, RVH was differentiated from intrinsic renal disease by obtaining a baseline renogram without ACE inhibition and comparing RCA in that study and RCA after ACE inhibition. If RCA increased (indicating worsening renal function) after ACE inhibition, RVH was likely; whereas, intrinsic renal disease was more likely if RCA remained unchanged or decreased (indicating improved renal function) with ACE inhibition. The test had a specificity of 95% and a sensitivity of 96% in this population. There was a direct correlation between the results of angioplasty or surgery on high blood pressure and the changes in RCA before and after intervention (n = 20)

  15. Properties of high-workability concrete with recycled concrete aggregate

    OpenAIRE

    Safiuddin,; Alengaram,Ubagaram Johnson; Salam,Abdus; Jumaat,Mohd Zamin; Jaafar,Fahrol Fadhli; Saad,Hawa Binti

    2011-01-01

    This study presents the effects of recycled concrete aggregate (RCA) on the key fresh and hardened properties of concrete. RCA was used to produce high-workability concrete substituting 0-100% natural coarse aggregate (NCA) by weight. The slump and slump flow of fresh concretes were determined to ensure high workability. In addition, the compressive, flexural and splitting tensile strengths, modulus of elasticity, and permeable voids of hardened concretes were determined. The test results rev...

  16. Curvilinear 3-D Imaging Using Row--Column-Addressed 2-D Arrays with a Diverging Lens: Feasibility Study

    DEFF Research Database (Denmark)

    Bouzari, Hamed; Engholm, Mathias; Beers, Christopher

    2017-01-01

    imaging. Extended FOV and low channel count of double-curved RCA 2-D arrays make 3-D imaging possible with equipment in the price range of conventional 2-D imaging. This study proposes a delay-and-sum beamformation scheme specific to double-curved RCA 2-D arrays and validates its focusing ability based...... of this study demonstrate that the proposed beamforming approach is accurate for achieving correct time-of-flight calculations, and hence avoids geometrical distortions....

  17. [Inhibition by cysteine of the carbohydrate-binding activity of lectins from Ricinus communis, Canavalia ensiformis and Euonymus europaeus].

    Science.gov (United States)

    Dvorkin, V M

    1985-10-01

    Precipitation induced by different lectins has been studied in the presence of some aminoacids. It was shown that precipitates formed by lectins from Ricinus communis (RCA1), Canavalia ensiformis (Con A), Euonymus europaeus (Eel) in the presence of appropriate carbohydrate-containing molecules disappeared after cysteine addition, like after addition of specific carbohydrate precipitation inhibitors. It is assumed that cysteine residues of RCA1, Con A and Eel lectins are essential for their carbohydrate binding activity.

  18. Chemical-mineralogical characterisation of coarse recycled concrete aggregate

    International Nuclear Information System (INIS)

    Limbachiya, M.C.; Marrocchino, E.; Koulouris, A.

    2007-01-01

    The construction industry is now putting greater emphasis than ever before on increasing recycling and promoting more sustainable waste management practices. In keeping with this approach, many sectors of the industry have actively sought to encourage the use of recycled concrete aggregate (RCA) as an alternative to primary aggregates in concrete production. The results of a laboratory experimental programme aimed at establishing chemical and mineralogical characteristics of coarse RCA and its likely influence on concrete performance are reported in this paper. Commercially produced coarse RCA and natural aggregates (16-4 mm size fraction) were tested. Results of X-ray fluorescence (XRF) analyses showed that original source of RCA had a negligible effect on the major elements and a comparable chemical composition between recycled and natural aggregates. X-ray diffraction (XRD) analyses results indicated the presence of calcite, portlandite and minor peaks of muscovite/illite in recycled aggregates, although they were directly proportioned to their original composition. The influence of 30%, 50%, and 100% coarse RCA on the chemical composition of equal design strength concrete has been established, and its suitability for use in a concrete application has been assessed. In this work, coarse RCA was used as a direct replacement for natural gravel in concrete production. Test results indicated that up to 30% coarse RCA had no effect on the main three oxides (SiO 2 , Al 2 O 3 and CaO) of concrete, but thereafter there was a marginal decrease in SiO 2 and increase in Al 2 O 3 and CaO contents with increase in RCA content in the mix, reflecting the original constituent's composition

  19. Chemical-mineralogical characterisation of coarse recycled concrete aggregate.

    Science.gov (United States)

    Limbachiya, M C; Marrocchino, E; Koulouris, A

    2007-01-01

    The construction industry is now putting greater emphasis than ever before on increasing recycling and promoting more sustainable waste management practices. In keeping with this approach, many sectors of the industry have actively sought to encourage the use of recycled concrete aggregate (RCA) as an alternative to primary aggregates in concrete production. The results of a laboratory experimental programme aimed at establishing chemical and mineralogical characteristics of coarse RCA and its likely influence on concrete performance are reported in this paper. Commercially produced coarse RCA and natural aggregates (16-4 mm size fraction) were tested. Results of X-ray fluorescence (XRF) analyses showed that original source of RCA had a negligible effect on the major elements and a comparable chemical composition between recycled and natural aggregates. X-ray diffraction (XRD) analyses results indicated the presence of calcite, portlandite and minor peaks of muscovite/illite in recycled aggregates, although they were directly proportioned to their original composition. The influence of 30%, 50%, and 100% coarse RCA on the chemical composition of equal design strength concrete has been established, and its suitability for use in a concrete application has been assessed. In this work, coarse RCA was used as a direct replacement for natural gravel in concrete production. Test results indicated that up to 30% coarse RCA had no effect on the main three oxides (SiO2, Al2O3 and CaO) of concrete, but thereafter there was a marginal decrease in SiO2 and increase in Al2O3 and CaO contents with increase in RCA content in the mix, reflecting the original constituent's composition.

  20. Integration of Tax Administration to Curb Import and Domestic Tax Evasions in Ghana

    OpenAIRE

    John Adu Kwame; Eric Tutu Tchao; Kwasi Poku

    2013-01-01

    As part of the Government of Ghana’s plans to maximize tax mobilization, it recently integrated its Regional Collection Agencies (RCA) namely; the Internal Revenue Service (IRS), Customs Excise and Preventive service (CEPS) and the Value Added Tax (VAT) Services into the Ghana Revenue Authority (GRA). This research aims to find out whether Ghana’s tax administration reform of integrating the RCA into GRA has dealt with the inefficiencies in tax administration with respect to personal income t...

  1. Features of electrocardiogram in patients with stenosis of the proximal right coronary artery.

    Science.gov (United States)

    Koh, Moo Seong; Lee, Jae Hoon; Jeong, Jin Woo; Chung, Jun Young

    2017-03-01

    Prediction of lesions of the proximal right coronary artery (pRCA) through electrocardiogram (ECG) is very important because pRCA occlusion has many complications and a high mortality rate, which has frequently been related with right ventricular infarction. The purpose of this study was to devise a screening tool that takes into account multiple leads from a 12-lead ECG to predict the pRCA lesion. A hundred and fifty-eight patients who were diagnosed as acute coronary syndrome and had a pure lesion of RCA or left circumf lex artery (LCX) by ECGs and angiographic findings were enrolled retrospectively. Forty-eight patients with a pure pRCA occlusion were compared to a control group of 110 patients who were diagnosed as having either a pure mid to distal RCA lesion (57 patients) or a pure LCX lesion (53 patients). ECGs of patients in the pRCA group showed more prominent ST depression in lead I ( p = 0.001) and ST elevation in V1 ( p = 0.002) than in the control group. The combination of ST depression (≤ 0 mm) in I and ST elevation (> 0.5 mm) in V1 was the best diagnostic tool (area under the curve, 0.84). ST changes in leads V1 and I allow more accurate prediction of pRCA occlusion than other criteria, such as the difference between ST elevation of leads II and III or vector direction and amplitude. These variables could help to screen for right ventricular infarction before performing reverse ECG and predicting prognosis.

  2. Furosemide- sup 131 I-hippuran renography after angiotensin-converting enzyme inhibition for the diagnosis of renovascular hypertension

    Energy Technology Data Exchange (ETDEWEB)

    Erbsloeh-Moeller, B.Du.; Dumas, A.; Roth, D.; Sfakianakis, G.N.; Bourgoignie, J.J. (Univ. of Miami/Jackson Memorial Medical Center, FL (USA))

    1991-01-01

    We have previously demonstrated the greater sensitivity of 131I-hippuran renography than 99mTC-DTPA scintigraphy to diagnose renovascular hypertension (RVH). This study assesses the predictive diagnostic value of furosemide-131I-hippuran renography after angiotensin-converting enzyme (ACE) inhibition in patients with and without RVH. All patients were investigated at the University of Miami/Jackson Memorial Medical Center. Twenty-eight patients had RVH and 22 did not. Twenty-eight patients had normal or minimally decreased renal function and 22 had renal insufficiency. Renography was performed 60 minutes after oral administration of 50 mg captopril or 10 minutes after intravenous injection of 40 micrograms/kg enalaprilat. Forty milligrams of furosemide were administered intravenously 2 minutes after injection of 131I-hippuran. The residual cortical activity (RCA) of 131I-hippuran was measured at 20 minutes. RVH was unlikely when RCA after ACE inhibition was less than 30% of peak cortical activity. Conversely, RVH was present when 131I-hippuran cortical activity steadily increased throughout the test to reach 100% at 20 minutes. In azotemic patients with RCA between 31% and 100%, RVH was differentiated from intrinsic renal disease by obtaining a baseline renogram without ACE inhibition and comparing RCA in that study and RCA after ACE inhibition. If RCA increased (indicating worsening renal function) after ACE inhibition, RVH was likely; whereas, intrinsic renal disease was more likely if RCA remained unchanged or decreased (indicating improved renal function) with ACE inhibition. The test had a specificity of 95% and a sensitivity of 96% in this population. There was a direct correlation between the results of angioplasty or surgery on high blood pressure and the changes in RCA before and after intervention (n = 20).

  3. [Reshaping the left Judkins catheter for a right coronary angiogram in the anomalous aortic origin of the right coronary: killing two birds with one left Judkins].

    Science.gov (United States)

    Akgün, Taylan; Tanboğa, Ibrahim Halil; Oduncu, Vecih; Kurt, Mustafa; Cimen, Arif Oğuzhan; Bitigen, Atila

    2012-09-01

    Selective cannulation of the right coronary artery (RCA) in the anomalous aortic origin of the RCA is technically difficult and challenging. In this study, we tested the success of RCA cannulation with a reshaped left Judkins catheter in cases of difficult selective cannulation. The study population consisted of 837 consecutive patients (456 male, 381 female) that were admitted to our hospital with stable angina pectoris and acute coronary syndrome between October 1 and December 31, 2011. In cases where RCA cannulation was difficult, the 10 centimeter section of the left Judkins proximal to the secondary curve was reshaped by hand to form an inward slope. The secondary curve angle was increased to approximately 100 degrees and the primary curve angle was adjusted to 120 degrees. Then, we attempted to perform selective RCA cannulation. In 49 of the 837 patients, selective RCA cannulation was unsuccessful with the right Judkins catheter. In 42 of these 49 (86%) cases, the RCA was cannulated with the reshaped left Judkins. We failed to cannulate the right coronary in two cases with downward angulation, one with upward angulation, one with high take-off origin, and one with anterior origin. A multipurpose, internal mammary artery, left Amplatz 1, and right Amplatz 1 catheter were used for cannulation in these cases, respectively. There was no angina, nor were there electrocardiographic or hemodynamic changes during the procedure. In cases where the selective cannulation of the RCA is difficult, using a reshaped left Judkins may be a successful and cost-effective method of selective cannulation.

  4. Evaluation of rainfall simulations over West Africa in dynamically downscaled CMIP5 global circulation models

    Science.gov (United States)

    Akinsanola, A. A.; Ajayi, V. O.; Adejare, A. T.; Adeyeri, O. E.; Gbode, I. E.; Ogunjobi, K. O.; Nikulin, G.; Abolude, A. T.

    2018-04-01

    This study presents evaluation of the ability of Rossby Centre Regional Climate Model (RCA4) driven by nine global circulation models (GCMs), to skilfully reproduce the key features of rainfall climatology over West Africa for the period of 1980-2005. The seasonal climatology and annual cycle of the RCA4 simulations were assessed over three homogenous subregions of West Africa (Guinea coast, Savannah, and Sahel) and evaluated using observed precipitation data from the Global Precipitation Climatology Project (GPCP). Furthermore, the model output was evaluated using a wide range of statistical measures. The interseasonal and interannual variability of the RCA4 were further assessed over the subregions and the whole of the West Africa domain. Results indicate that the RCA4 captures the spatial and interseasonal rainfall pattern adequately but exhibits a weak performance over the Guinea coast. Findings from the interannual rainfall variability indicate that the model performance is better over the larger West Africa domain than the subregions. The largest difference across the RCA4 simulated annual rainfall was found in the Sahel. Result from the Mann-Kendall test showed no significant trend for the 1980-2005 period in annual rainfall either in GPCP observation data or in the model simulations over West Africa. In many aspects, the RCA4 simulation driven by the HadGEM2-ES perform best over the region. The use of the multimodel ensemble mean has resulted to the improved representation of rainfall characteristics over the study domain.

  5. A new member of a family of ATPases is essential for assembly of mitochondrial respiratory chain and ATP synthetase complexes in Saccharomyces cerevisiae.

    Science.gov (United States)

    Tzagoloff, A; Yue, J; Jang, J; Paul, M F

    1994-10-21

    Respiration-defective pet mutants of Saccharomyces cerevisiae, assigned to complementation group G25, are grossly deficient in mitochondrial respiratory and ATPase complexes. This phenotype is usually found in strains impaired in mitochondrial protein synthesis. The G25 mutants, however, synthesize all of the proteins encoded by mitochondrial DNA. The mutants are also able to import and process cytoplasmically derived subunits of these enzymes. These results are most compatible with the idea that the gene defined by G25 mutants (RCA1) codes for a protein essential for the assembly of functional respiratory and ATPase complexes. The RCA1 gene has been cloned by complementation of an rca1 mutant with a yeast genomic library. The sequence of the encoded product shows Rca1 protein to be a new member of a recently described family of ATPases. The Rca1 protein is a mitochondrial membrane protein and is the third known member of this family implicated to function in the biogenesis of mitochondria. The primary structure of Rca1 protein indicates several distinct domains in addition to the common purine nucleotide binding region shared by all members of this protein family. One, located in the amino-terminal half, contains two hydrophobic stretches of sufficient length to span a membrane lipid bilayer.

  6. Characterization of Ricin and R. communis Agglutinin Reference Materials

    Science.gov (United States)

    Worbs, Sylvia; Skiba, Martin; Söderström, Martin; Rapinoja, Marja-Leena; Zeleny, Reinhard; Russmann, Heiko; Schimmel, Heinz; Vanninen, Paula; Fredriksson, Sten-Åke; Dorner, Brigitte G.

    2015-01-01

    Ricinus communis intoxications have been known for centuries and were attributed to the toxic protein ricin. Due to its toxicity, availability, ease of preparation, and the lack of medical countermeasures, ricin attracted interest as a potential biological warfare agent. While different technologies for ricin analysis have been established, hardly any universally agreed-upon “gold standards” are available. Expert laboratories currently use differently purified in-house materials, making any comparison of accuracy and sensitivity of different methods nearly impossible. Technically challenging is the discrimination of ricin from R. communis agglutinin (RCA120), a less toxic but highly homologous protein also contained in R. communis. Here, we established both highly pure ricin and RCA120 reference materials which were extensively characterized by gel electrophoresis, liquid chromatography-electrospray ionization-tandem mass spectrometry (LC-ESI MS/MS), and matrix-assisted laser desorption ionization–time of flight approaches as well as immunological and functional techniques. Purity reached >97% for ricin and >99% for RCA120. Different isoforms of ricin and RCA120 were identified unambiguously and distinguished by LC-ESI MS/MS. In terms of function, a real-time cytotoxicity assay showed that ricin is approximately 300-fold more toxic than RCA120. The highly pure ricin and RCA120 reference materials were used to conduct an international proficiency test. PMID:26703723

  7. Engineering Behavior of Concrete with Recycled Aggregate

    Directory of Open Access Journals (Sweden)

    Ayob Afizah

    2017-01-01

    Full Text Available Concrete is extensively used as construction materials in Malaysia. Concrete contributes suitable feature for construction industry for instance durability, adequate compressive strength, fire resistance, availability and is economic as compared to other construction materials. Depletion of natural resources and disposal of construction and demolition waste remarkably claim environmental threat. In this paper, the engineering behavior, durability, and concrete microstructure of recycled concrete aggregates (RCA on short-term concrete properties were investigated. The studied concrete at design mix proportion of 1:0.55:2.14:2.61 (weight of cement :coarse aggregates :sand :water used to obtain medium-high compressive strength with 20%, 50%, and 100% of RCA. Results show that for the same water/cement ratio, RCA replacement up to 50% still achieved the targeted compressive strength of 25 MPa at 28 curing days. Addition, at similar RCA replacement, the highest carbonation depth value was found at 1.03 mm which could be attributed to the pozzolanic reaction, thus led to lower carbonation resistance. Scanning electron microscopy microstructure shows that the RCA surface was porous and covered with loose particles. Moreover, the interfacial transition zone was composed of numerous small pores, micro cracks, and fissures that surround the mortar matrix. On the basis of the obtained results, recommendable mineral admixtures of RCA are necessary to enhance the quality of concrete construction.

  8. Compressive strength and resistance to chloride ion penetration and carbonation of recycled aggregate concrete with varying amount of fly ash and fine recycled aggregate.

    Science.gov (United States)

    Sim, Jongsung; Park, Cheolwoo

    2011-11-01

    Construction and demolition waste has been dramatically increased in the last decade, and social and environmental concerns on the recycling have consequently been increased. Recent technology has greatly improved the recycling process for waste concrete. This study investigates the fundamental characteristics of concrete using recycled concrete aggregate (RCA) for its application to structural concrete members. The specimens used 100% coarse RCA, various replacement levels of natural aggregate with fine RCA, and several levels of fly ash addition. Compressive strength of mortar and concrete which used RCA gradually decreased as the amount of the recycled materials increased. Regardless of curing conditions and fly ash addition, the 28 days strength of the recycled aggregate concrete was greater than the design strength, 40 MPa, with a complete replacement of coarse aggregate and a replacement level of natural fine aggregate by fine RCA up to 60%. The recycled aggregate concrete achieved sufficient resistance to the chloride ion penetration. The measured carbonation depth did not indicate a clear relationship to the fine RCA replacement ratio but the recycled aggregate concrete could also attain adequate carbonation resistance. Based on the results from the experimental investigations, it is believed that the recycled aggregate concrete can be successfully applied to structural concrete members. Copyright © 2011 Elsevier Ltd. All rights reserved.

  9. Characterization of Ricin and R. communis Agglutinin Reference Materials

    Directory of Open Access Journals (Sweden)

    Sylvia Worbs

    2015-11-01

    Full Text Available Ricinus communis intoxications have been known for centuries and were attributed to the toxic protein ricin. Due to its toxicity, availability, ease of preparation, and the lack of medical countermeasures, ricin attracted interest as a potential biological warfare agent. While different technologies for ricin analysis have been established, hardly any universally agreed-upon “gold standards” are available. Expert laboratories currently use differently purified in-house materials, making any comparison of accuracy and sensitivity of different methods nearly impossible. Technically challenging is the discrimination of ricin from R. communis agglutinin (RCA120, a less toxic but highly homologous protein also contained in R. communis. Here, we established both highly pure ricin and RCA120 reference materials which were extensively characterized by gel electrophoresis, liquid chromatography-electrospray ionization-tandem mass spectrometry (LC-ESI MS/MS, and matrix-assisted laser desorption ionization–time of flight approaches as well as immunological and functional techniques. Purity reached >97% for ricin and >99% for RCA120. Different isoforms of ricin and RCA120 were identified unambiguously and distinguished by LC-ESI MS/MS. In terms of function, a real-time cytotoxicity assay showed that ricin is approximately 300-fold more toxic than RCA120. The highly pure ricin and RCA120 reference materials were used to conduct an international proficiency test.

  10. DAYA SAING EKSPOR TUNA KALENG INDONESIA DI UNI EROPA TAHUN 2003-2013

    Directory of Open Access Journals (Sweden)

    Umar Wahono

    2017-06-01

    Full Text Available Perbedaan tarif yang diberikan antara Indonesia yang lebih tinggi sebesar 20.5% dibandingkan dengan negara pesaing utamanya yang tergabung dalang Africa, Caribbean, Pasific (ACP Countries dengan pelayanan tarif impor hingga 0% ke pasar Uni Eropa (UE. Keadaan ini mampu menyebabkan menghilangnya distorsi perbedaan harga sesungguhnya yang seharusnya menjadi keuntungan lebih atas keunggulan komparatif yang dimiliki. Hal ini mampu melemahkan daya saing komoditi ekspor akibat dampak kenaikan harga terhadap tarif. Penelitian ini bertujuan untuk gambaran daya saing komoditas tuna kaleng Indonesia terhadap negara pesaingnya dipasar UE pada periode 2003-2013. Metode yang digunakan dalam penelitin ini adalah metode Revealed Comparative Advantage (RCA yang kemudian nilai RCA dikomparasikan tiap-tiap negara pengekspor utama tuna kaleng di pasar UE untuk melihat posisi daya saing relatifnya. Sedangkan untuk mendekomposisikan determinan pertumbuhan ekspor tuna kaleng Indonesia ke UE digunankan metode Constant Market Share (CMS. Hasil perhitungan nilai RCA tuna kaleng Indonesia periode 2003-2013 di pasar UE memiliki daya saing dengan rata-rata nilai RCA 4.27. Namun masih dibawah rata-rata nilai RCA negara ACP Countries. Perbedaan pelayanan tarif impor oleh UE untuk komoditas tuna kaleng Indonesia tidak berdampak terhadap penurunan daya saing. The difference between the rates given Indonesia which is higher by 20.5% compared to its main competitor countries that joined the mastermind Africa, Caribbean, Pacific (ACP Countries with service import tariffs to 0% to the European Union (EU. This situation is capable of causing the disappearance of the distortion of the true price difference should be more advantages over comparative advantage. It is capable of undermining the competitiveness of export commodities due to the impact of price increases on tariffs. This study aims to illustrate the competitiveness of commodities Indonesian canned tuna to the EU market of

  11. Effect of curd washing on the properties of reduced-calcium and standard-calcium Cheddar cheese.

    Science.gov (United States)

    Hou, Jia; McSweeney, Paul L H; Beresford, Thomas P; Guinee, Timothy P

    2014-10-01

    Washed (W) and nonwashed (NW) variants of standard (SCa) and reduced-calcium (RCa) Cheddar cheeses were made in triplicate, ripened for a 270-d period, and analyzed for composition and changes during maturation. Curd washing was applied to cheeses to give a target level of lactose plus lactic acid in cheese moisture of 3.9 g/100 g in the W cheese, compared with a value of 5.3 g/100 g of lactose plus lactic acid in cheese moisture in the control NW cheeses. The 4 cheese types were denoted standard calcium nonwashed (SCaNW), standard calcium washed (SCaW), reduced-calcium nonwashed (RCaNW), and reduced-calcium washed (RCaW). The mean calcium level was 760 mg/100 g in the SCaNW and SCaW and 660 mg/100 g in the RCaNW and RCaW cheeses. Otherwise the gross composition of all cheeses was similar, each with protein, fat, and moisture levels of ~26, 32, and 36 g/100 g, respectively. Curd washing significantly reduced the mean level of lactic acid in the SCaW cheese and residual lactose in both SCaW and RCaW cheeses. The mean pH of the standard-calcium cheese over the 270-d ripening period increased significantly with curd washing and ripening time, in contrast to the reduced-calcium cheese, which was not affected by the latter parameters. Otherwise curd washing had little effect on changes in populations of starter bacteria or nonstarter lactic acid bacteria, proteolysis, rheology, or color of the cheese during ripening. Descriptive sensory analysis at 270 d indicated that the SCaW cheese had a nuttier, sweeter, less fruity, and less rancid taste than the corresponding SCaNW cheese. In contrast, curd washing was not as effective in discriminating between the RCaW and RCaNW cheeses. The RCaW cheese had a more buttery, caramel odor and flavor, and a more bitter, less sweet, and nutty taste than the SCaW cheese, whereas the RCaNW had a more pungent and less fruity flavor, a less fruity odor, a saltier, more-bitter, and less acidic taste, and a more astringent mouthfeel than

  12. Economic Liberalism and Regional Security in East Asia: A Case Study on the Impact of China’s Accession to the WTO

    Science.gov (United States)

    2010-12-10

    And finally, I save the last word for Mrs. Venita Krueger whom I believe has the entire Turabian manual stored in her memory, and whose meticulousness...telecommunications, financial services, agriculture, retail , and entertainment sectors. Other political issues that were thrown into the fray and...finance. In contrast, middle-income countries such as Indonesia, Malaysia , and Thailand were expected to receive a mixed impact due to their similarity in

  13. Teresa y Luis, Luis y Teresa. Dos santos en tiempos recios

    Directory of Open Access Journals (Sweden)

    Emilio Callado Estela

    2016-06-01

    Full Text Available El presente artículo analiza la relación entre dos grandes santos españoles de la Contrarreforma Católica, Teresa de Jesús y el dominico fray Luis Bertrán. The present article analyses the relation between two big Spanish saints of the Catholic Counterreformation, Teresa de Jesus and the Dominican monk Luis Bertrán.

  14. Sub-Saharan Africa Report, No. 2826

    Science.gov (United States)

    1983-07-27

    Begins Housing Sales to Blacks (Johannesburg Domestic Service, 1 Jul 83) 79 Roles of Black Farmers, U.S. Firms Discussed (SAPA, 7 Jul 83...advanced technology and superpowers. Yet how many in Africa will share his sentiment if only because it is a necessary subject about which to talk and...some of the shocks, and prevent a dangerous internationalisation . Col. Mengistu, the new OAU Chairman, who has entered the fray to criticise Zaire’s

  15. Biological Inspiration for Agile Autonomous Air Vehicles

    Science.gov (United States)

    2007-11-01

    half of one wing, bees with legs packed with pollen , butterflies or moths with torn and frayed wings likewise are capable of apparently normal flight...technologies. To appreciate this, consider a not unreasonable extension of a wide area autonomous search (WAAS) munition operational scenario. Here...detect and destroy missile launchers that are operating in the back alleys of an urban areas or search Evers, J.H. (2007) Biological Inspiration for Agile

  16. Ecclesiastical Architecture and the Castilian Crisis of the Seventeenth Century: Seville Cathedral and the Church of the Sagrario.

    OpenAIRE

    d'Arcy, Sing

    2014-01-01

    When it came time for the critics and historiographers of the late eighteenth and early nineteenth centuries to write the grand narrative of Spanish architecture, the decadence of Habsburg monarchy, economy and society was paralleled to the decline of the noble art itself. The completion of the Escorial in 1584 loomed more like an enormous granite epitaph for Spanish architectural production than the promise of a New Jerusalem. For seventeenth-century architects and theoreticians, like Fray L...

  17. FOCUS THE CONSUMER MARKET A dream or reality for multinational companies

    Institute of Scientific and Technical Information of China (English)

    MICHAELO'NEILL

    2004-01-01

    As the Chinese economy maintains its near double digit growth, opportunities for foreign investors continue to emerge. But away from the staggering statistics, how realistic is the China dream for multinational companies (MNCs)? The messages are mixed. On the one hand are those who continue to hail the Chinese consumer revolution, pointing to market size as reason enough for entering the fray. O'n the other

  18. Effects of radiation therapy on growing long bones

    International Nuclear Information System (INIS)

    De Smet, A.A.; Kuhns, L.R.; Fayos, J.V.; Holt, J.F.

    1976-01-01

    Characteristic radiographic changes were seen in six of 14 children who received radiation therapy to the epiphyseal plate of a long bone. These changes, which include metaphyseal sclerosis, metaphyseal fraying, and epiphyseal plate widening, resemble rickets. In three patients, these changes were followed by development of a broad metaphyseal band of increased density. The absence of metaphyseal changes may indicate sterilization of cartilage cells and may be predictive of significant limb shortening

  19. Handbook For Military Justice and Civil Law

    Science.gov (United States)

    1996-02-01

    to supporting her six kids . Noticing that his uniforms are becoming quite frayed (apparently because of the parade of little bodies jumping into...which a substance was packaged; and the fact that an accused was not normally a user. The fact that an accused was addicted to or was a heavy user...Article 510.68 of OPNAVINST 3120.32, Subj: STANDARD ORGANIZATION AND REGULATIONS OF THE U.S. NAVY no longer prohibits the possession of pornography on

  20. A Question of Heroines

    Directory of Open Access Journals (Sweden)

    Jaime Oscar M. Salazar

    2014-06-01

    Full Text Available Ang Kababaihan ng Malolos (2014. 85 minutes. Color. Directed by Sari Dalena and Kiri Dalena. Written and produced by Nicanor Tiongson. Cinematography by Kiri Dalena. Starring Hazel Faith dela Cruz as Basilia Villariño Tantoco, Karl Medina as Jose Rizal, Bong Enriquez as Governor-General Valeriano Weyler, and Carlos Celdran as Fray Felipe Garcia. Edited by Keith Sicat and Joris Fernandez. Philippines: Ambassador Bienvenido R. Tantoco Sr.

  1. Sequence-Dependent Mechanism of DNA Oligonucleotide Dehybridization Resolved through Infrared Spectroscopy.

    Science.gov (United States)

    Sanstead, Paul J; Stevenson, Paul; Tokmakoff, Andrei

    2016-09-14

    Despite its important role in biology and nanotechnology, many questions remain regarding the molecular mechanism and dynamics by which oligonucleotides recognize and hybridize to their complementary sequence. The thermodynamics and kinetics of DNA oligonucleotide hybridization and dehybridization are often assumed to involve an all-or-nothing two-state dissociation pathway, but deviations from this behavior can be considerable even for short sequences. We introduce a new strategy to characterize the base-pair-specific thermal dissociation mechanism of DNA oligonucleotides through steady-state and time-resolved infrared spectroscopy. Experiments are interpreted with a lattice model to provide a structure-specific interpretation. This method is applied to a model set of self-complementary 10-base-pair sequences in which the placement of GC base pairs is varied in an otherwise AT strand. Through a combination of Fourier transform infrared and two-dimensional infrared spectroscopy, experiments reveal varying degrees of deviation from simple two-state behavior. As the temperature is increased, duplexes dissociate through a path in which the terminal bases fray, without any significant contribution from loop configurations. Transient temperature jump experiments reveal time scales of 70-100 ns for fraying and 10-30 μs for complete dissociation near the melting temperature. Whether or not frayed states are metastable intermediates or short-lived configurations during the full dissociation of the duplex is dictated by the nucleobase sequence.

  2. Retrospective cost adaptive Reynolds-averaged Navier-Stokes k-ω model for data-driven unsteady turbulent simulations

    Science.gov (United States)

    Li, Zhiyong; Hoagg, Jesse B.; Martin, Alexandre; Bailey, Sean C. C.

    2018-03-01

    This paper presents a data-driven computational model for simulating unsteady turbulent flows, where sparse measurement data is available. The model uses the retrospective cost adaptation (RCA) algorithm to automatically adjust the closure coefficients of the Reynolds-averaged Navier-Stokes (RANS) k- ω turbulence equations to improve agreement between the simulated flow and the measurements. The RCA-RANS k- ω model is verified for steady flow using a pipe-flow test case and for unsteady flow using a surface-mounted-cube test case. Measurements used for adaptation of the verification cases are obtained from baseline simulations with known closure coefficients. These verification test cases demonstrate that the RCA-RANS k- ω model can successfully adapt the closure coefficients to improve agreement between the simulated flow field and a set of sparse flow-field measurements. Furthermore, the RCA-RANS k- ω model improves agreement between the simulated flow and the baseline flow at locations at which measurements do not exist. The RCA-RANS k- ω model is also validated with experimental data from 2 test cases: steady pipe flow, and unsteady flow past a square cylinder. In both test cases, the adaptation improves agreement with experimental data in comparison to the results from a non-adaptive RANS k- ω model that uses the standard values of the k- ω closure coefficients. For the steady pipe flow, adaptation is driven by mean stream-wise velocity measurements at 24 locations along the pipe radius. The RCA-RANS k- ω model reduces the average velocity error at these locations by over 35%. For the unsteady flow over a square cylinder, adaptation is driven by time-varying surface pressure measurements at 2 locations on the square cylinder. The RCA-RANS k- ω model reduces the average surface-pressure error at these locations by 88.8%.

  3. Effects of nicorandil on coronary collateral circulation depend on the donor arteries

    International Nuclear Information System (INIS)

    Umezawa, Shigeo; Ogawara, Shigeko; Okamoto, Yoshihiro; Igawa, Masayuki; Aonuma, Kazutaka; Inada, Mihoe; Korenaga, Masayoshi; Hiroe, Michiaki; Marumo, Fumiaki.

    1996-01-01

    The effects of nicorandil on coronary collateral circulation during exercise-induced ischemia were compared between the different donor arteries in 13 patients with effort angina, 7 with complete obstruction of the left anterior descending artery (LAD) with well-developed collateral vessels from the right coronary artery (RCA) (LAD group), and 6 with complete occlusion of the RCA (segment 2-3) with well-developed collateral vessels from the LAD (RCA group). Initial percentage thallium (%Tl) uptake (thallium-201 single photon emission computed tomography) and washout rate were measured in the anterior, septal and posterior regions during ergometer exercise. The submaximal treadmill exercise test was also performed using a cardiopulmonary monitoring system to measure Vo 2 at anaerobic threshold (AT). After the controls were obtained, nicorandil (15 mg/day) was administered for 4 weeks, during which ergometer exercise and treadmill exercise tests were carried out repeatedly. A significant improvement of initial %Tl uptake on exercise was observed in the LAD group with nicorandil therapy, but no improvement was shown in the RCA group. The AT significantly increased after nicorandil treatment in the LAD group (13.9±0.38 → 16.8±1.18 ml/min/kg), reflecting the improvement of cardiac function through the increased collateral flow. However, in the RCA group, it remained unchanged, suggesting no improvement of cardiac function. Nicorandil was effective to increase collateral flow from the RCA, but ineffective on that from the LAD. Nicorandil is an effective coronary dilator and is reported to affect both large and small coronary arteries. The effect on the collateral circulation is dependent on the donor artery supplying different areas. The vasodilator effect of nicorandil is mainly on the LAD, which is large enough to supply blood to a wider area of the heart, rather than the RCA. (author)

  4. Molecular and biochemical characterization of carbonic anhydrases of Paracoccidioides

    Directory of Open Access Journals (Sweden)

    Mariana Vieira Tomazett

    Full Text Available Abstract Carbonic anhydrases (CA belong to the family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide to bicarbonate. In the present work, we characterized the cDNAs of four Paracoccidioides CAs (CA1, CA2, CA3, and CA4. In the presence of CO2, there was not a significant increase in fungal ca1, ca2 and ca4 gene expression. The ca1 transcript was induced during the mycelium-to-yeast transition, while ca2 and ca4 gene expression was much higher in yeast cells, when compared to mycelium and mycelium-to-yeast transition. The ca1 transcript was induced in yeast cells recovered directly from liver and spleen of infected mice, while transcripts for ca2 and ca4 were down-regulated. Recombinant CA1 (rCA1 and CA4 (rCA4, with 33 kDa and 32 kDa respectively, were obtained from bacteria. The enzymes rCA1 (β-class and rCA4 (α-class were characterized regarding pH, temperature, ions and amino acids addition influence. Both enzymes were stable at pHs 7.5-8.5 and temperatures of 30-35 °C. The enzymes were dramatically inhibited by Hg+2 and activated by Zn+2, while only rCA4 was stimulated by Fe2+. Among the amino acids tested (all in L configuration, arginine, lysine, tryptophan and histidine enhanced residual activity of rCA1 and rCA4.

  5. The competitiveness of wood processing industry in the Republic of Serbia during the period 1995-2015

    Directory of Open Access Journals (Sweden)

    Milićević Srđan

    2017-01-01

    Full Text Available The paper considers the competitiveness of wood processing industry in the Republic of Serbia in the period 1995-2015 by using six partial indicators of competitiveness: Revealed comparative advantage (RCA, Competitiveness growth index (RCA1, Index of net business performance (RCA2, Index of contribution to the trade balance (CTB, Grubel-Lloyd index (GLI and Michaely index (MI. The research reveals that the values of RCA were positive in all years, which points to comparative advantage of wood processing industry on the domestic market. Since RCA1 has significantly higher value than one, it means that it is highly competitive on international market as well. Positive values of RCA2 in the period 1995-2015 speak of the contribution of this branch to international economic balance. The indicator RCA2 is connected with the CTB index, which points to the contribution of the sector in formation of active national trade balance and economic growth. The average value of CTB index of wood processing industry in Serbia and positive annual values of CTB of wood processing industry show that the contribution in the total trade balance of the sector is positive. The course of GLI values points to the loss of capabilities of the sector to create the surplus of national trade balance. Finally, positive annual values of MI confirmed the competitiveness of domestic wood processing industry, but at the same time its low specialisation. Taken as a whole, the weakness of competitiveness of wood processing industry in Serbia can be seen in the fact that its competitive advantage is visible in its favourable price, not in manufacturing complex products with high value added. The aim of the paper is to investigate whether Serbian wood processing industry has comparative precedence on domestic and international markets and whether the structure of exchange is positive, i.e. whether appropriate specialisation of production and export exists or the focus should shift

  6. Molecular and biochemical characterization of carbonic anhydrases of Paracoccidioides.

    Science.gov (United States)

    Tomazett, Mariana Vieira; Zanoelo, Fabiana Fonseca; Bailão, Elisa Flávia Cardoso; Bailão, Alexandre Melo; Borges, Clayton Luiz; Soares, Célia Maria de Almeida

    2016-01-01

    Carbonic anhydrases (CA) belong to the family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide to bicarbonate. In the present work, we characterized the cDNAs of four Paracoccidioides CAs (CA1, CA2, CA3, and CA4). In the presence of CO2, there was not a significant increase in fungal ca1, ca2 and ca4 gene expression. The ca1 transcript was induced during the mycelium-to-yeast transition, while ca2 and ca4 gene expression was much higher in yeast cells, when compared to mycelium and mycelium-to-yeast transition. The ca1 transcript was induced in yeast cells recovered directly from liver and spleen of infected mice, while transcripts for ca2 and ca4 were down-regulated. Recombinant CA1 (rCA1) and CA4 (rCA4), with 33 kDa and 32 kDa respectively, were obtained from bacteria. The enzymes rCA1 (β-class) and rCA4 (α-class) were characterized regarding pH, temperature, ions and amino acids addition influence. Both enzymes were stable at pHs 7.5-8.5 and temperatures of 30-35 °C. The enzymes were dramatically inhibited by Hg+2 and activated by Zn+2, while only rCA4 was stimulated by Fe2+. Among the amino acids tested (all in L configuration), arginine, lysine, tryptophan and histidine enhanced residual activity of rCA1 and rCA4.

  7. Genetically encoded calcium indicators for multi-color neural activity imaging and combination with optogenetics

    Directory of Open Access Journals (Sweden)

    Jasper eAkerboom

    2013-03-01

    Full Text Available Genetically encoded calcium indicators (GECIs are powerful tools for systems neuroscience. Here we describe red, single-wavelength GECIs, RCaMPs, engineered from circular permutation of the thermostable red fluorescent protein mRuby. High-resolution crystal structures of mRuby, the red sensor RCaMP, and the recently published red GECI R-GECO1 give insight into the chromophore environments of the Ca2+-bound state of the sensors and the engineered protein domain interfaces of the different indicators. We characterized the biophysical properties and performance of RCaMP sensors in vitro and in vivo in Caenorhabditis elegans, Drosophila larvae, and larval zebrafish. Further, we demonstrate 2-color calcium imaging both within the same cell (registering mitochondrial and somatic [Ca2+] and between two populations of cells: neurons and astrocytes. Finally, we perform integrated optogenetics experiments, wherein neural activation via channelrhodopsin-2 (ChR2 or a red-shifted variant, and activity imaging via RCaMP or GCaMP, are conducted simultaneously, with the ChR2/RCaMP pair providing independently addressable spectral channels. Using this paradigm, we measure calcium responses of naturalistic and ChR2-evoked muscle contractions in vivo in crawling C. elegans. We systematically compare the RCaMP sensors to R-GECO1, in terms of action potential-evoked fluorescence increases in neurons, photobleaching, and photoswitching. R-GECO1 displays higher Ca2+ affinity and larger dynamic range than RCaMP, but exhibits significant photoactivation with blue and green light, suggesting that integrated channelrhodopsin-based optogenetics using R-GECO1 may be subject to artifact. Finally, we create and test blue, cyan and yellow variants engineered from GCaMP by rational design. This engineered set of chromatic variants facilitates new experiments in functional imaging and optogenetics.

  8. Characteristics of Recycled Concrete Aggregates from Precast Slab Block Buildings

    Science.gov (United States)

    Venkrbec, Václav; Nováková, Iveta; Henková, Svatava

    2017-10-01

    Precast slab block buildings (PSBB) typically and frequently occur in Central and Eastern Europe, as well as elsewhere in the world. Some of these buildings are currently used beyond their service life capacity. The utilization of recycled materials from these buildings with regard to applying the principles of sustainable construction and using recycled materials will probably be significant in the following years. Documentation from the manufacturing processes of prefabricated blocks for precast slab block buildings is not available, and also it is difficult to declare technological discipline during the construction of these buildings. Therefore, properties of recycled concrete aggregates (RCA) produced from construction and demolition waste (C&DW) of precast slab block buildings build between 1950s to 1990s are not sufficiently known. The demolition of these buildings is very rare today, but it can be assumed an increase in demolitions of these buildings in the future. The use of RCA in new concrete requires verification/testing of the geometrical and physical properties of RCA according to the EN 12 620+A1 standard. The aim of the contribution is to present a case study of the demolition of slab block building with emphasis on RCA usage. The paper presents the results of the tests according to European standards for determining selected geometrical and physical properties of the RCA. The paper describes and evaluates tests such as determination of particle size distribution - Sieve Analysis, content of fine particles, determination of density and water absorption. The results of the properties testing of RCA are compared with the properties of natural aggregate. The general boundary conditions of RCA particular tests are presented.

  9. Variación espacio-temporal de Chironomidae (Diptera bentónicos y derivantes en un arroyo serrano en Córdoba, Argentina

    Directory of Open Access Journals (Sweden)

    Juan P. Zanotto-Arpellino

    2015-03-01

    Full Text Available Chironomidae es una de las familias más abundantes y diversas en los ecosistemas de agua dulce, sin embargo su complejidad sistemática ha sido motivo de su escaso desarrollo en muchos estudios limnológicos. El objetivo de este estudio fue analizar los ensambles de Chironomidae bentónicos y derivantes de un arroyo serrano de la región central de Argentina evaluando abundancia, diversidad y composición de especies en diferentes hábitats fluviales y distintas estaciones del año. Se tomaron muestras cuantitativas de bentos y deriva en el arroyo Achiras (Córdoba, Argentina en hábitats de rabión y corredera, y se registraron variables ambientales en las cuatro estaciones del año, entre 2007 y 2008. Se registró un total de 25 taxones pertenecientes a cuatro subfamilias. Los quironómidos bentónicos constituyeron el 19% de la comunidad de macroinvertebrados, mientras que en deriva representaron el 33%. En el bentos dominó Thienemannimyia sp. y en la deriva, Corynoneura sp. De acuerdo con los resultados de ANOVAs de dos vías, los mayores valores de riqueza taxonómica y densidad bentónica se registraron en el periodo de aguas bajas (otoño e invierno y la diversidad de quirónomidos bentónicos fue mayor en rabión. Por el contrario, para el ensamble de derivantes sólo la equitatividad fue diferente entre hábitats y entre estaciones. El análisis TWINSPAN mostró una separación espacio-temporal de las muestras de bentos, mientras que las muestras de deriva se segregaron sólo temporalmente lo que sugiere que el transporte aguas abajo de los invertebrados homogeniza la variación espacial observada en el bentos. La densidad de bentos y deriva varió de manera similar a través de las estaciones del año y el coeficiente de Jaccard presentó un alto índice de similitud entre bentos y deriva (86%. Este trabajo posibilitó conocer la dinámica temporal y espacial de los quironómidos bentónicos y derivantes en un arroyo serrano. La

  10. Improving health care costing with resource consumption accounting.

    Science.gov (United States)

    Ozyapici, Hasan; Tanis, Veyis Naci

    2016-07-11

    Purpose - The purpose of this paper is to explore the differences between a traditional costing system (TCS) and resource consumption accounting (RCA) based on a case study carried out in a hospital. Design/methodology/approach - A descriptive case study was first carried out to identify the current costing system of the case hospital. An exploratory case study was then conducted to reveal how implementing RCA within the case hospital assigns costs differently to gallbladder surgeries than the current costing system (i.e. a TCS). Findings - The study showed that, in contrast to a TCS, RCA considers the unused capacity, which is the difference between the work that can be performed based on current resources and the work that is actually being performed. Therefore, it assigns lower total costs to open and laparoscopic gallbladder surgeries. The study also showed that by separating costs into fixed and variable RCA allows managers to benefit from a pricing strategy based on the difference between the service's selling price and variable costs incurred in providing that service. Research limitations/implications - The limitation of this study is that, because of time constraints, the implementation was performed in the general surgery department only. However, since RCA is an advanced system that has the same application procedures for any department inside in a hospital, managers need only time gaps to implement this system to all parts of the hospital. Practical implications - This study concluded that RCA is better than a TCS for use in health care settings that have high overhead costs because it accurately assigns overhead costs to services by considering unused capacities incurred by a hospital. Consequently, this study provides insight into both measuring and managing unused capacities within the health care sector. This study also concluded that RCA helps health care administrators increase their competitive advantage by allowing them to determine the lowest

  11. 16-slice multi-detector row CT coronary angiography: image quality and optimization of the image reconstruction window

    International Nuclear Information System (INIS)

    Kim, Yoo Kyung; Shim, Sung Shine; Lim, Soo Mee; Hwang, Ji Young; Kim, Yoon Kyung

    2005-01-01

    The purpose of this experiment is to investigate the image quality of CT coronary angiography using a 16-slice multi-detector row CT and to determine the optimal image reconstruction window. CT coronary angiography was obtained in 36 nonsymptomatic volunteers using a 16-slice multi-detector row CT (SOMATOM Sensation, Siemens Medical System). The mean heart rates were 70 beats per minute (bpm) or less in 18 persons and more than 70 bpm in 18 persons. Eleven data sets were obtained for each patient (reconstructed at 30%-80% of the cardiac cycle with an increment of 5%). Image quality of the eight coronary segments [left main coronary artery (LM), proximal and middle segments of left anterior descending artery (p-LAD, m-LAN) and left circumflex coronary artery (p-LCx, m-LCx) and proximal, middle and distal segments of right coronary artery (p-RCA, m-RCA, d-RCA)] was assessed. The optimal reconstruction windows in the cardiac cycle for the best image quality were 60-70% for the segments of the LM, LAD, and LC arteries in two groups (bpm 70) and 55-65% (bpm 70) for the segments of the RCA. On the best dataset for each coronary segment, the following diagnostic image quality was achieved in the two groups: LM: 100%, 83%; p-LAD: 100%, 88% m-LAD: 100%, 72%; p-LCx: 100%, 72%; m-LCx: 100%, 72%; p-RCA: 94%, 72%; m-RCA: 61%, 50%; d-RCA: 100%, 80%. The 16 slice multi-detector row CT scan provided visualization of the coronary arteries with high resolution. Especially in the group with a mean heart rate of 70 bpm or less, all the coronary segments except the RCA showed diagnostic image quality. Optimal image quality was achieved with a 60-70% trigger delay for all coronary arterial segments, but the best images of RCA were achieved in the earlier cardiac phase in the patients with a mean heart rate of more than 70 bpm

  12. Mechanical properties of recycled concrete with demolished waste concrete aggregate and clay brick aggregate

    Science.gov (United States)

    Zheng, Chaocan; Lou, Cong; Du, Geng; Li, Xiaozhen; Liu, Zhiwu; Li, Liqin

    2018-06-01

    This paper presents an experimental investigation on the effect of the replacement of natural coarse aggregate (NCA) with either recycled concrete aggregate (RCA) or recycled clay brick aggregate (RBA) on the compressive strengths of the hardened concrete. Two grades (C25 and C50) of concrete were investigated, which were achieved by using different water-to-cement ratios. In each grade concrete five different replacement rates, 0%, 25%, 50%, 75% and 100% were considered. In order to improve the performance of the recycled aggregates in the concrete mixes, the RCA and RBA were carefully sieved by using the optimal degradation. In this way the largest reduction in the 28-day compressive strength was found to be only 7.2% and 9.6% for C25 and C50 recycled concrete when the NCA was replaced 100% by RCA, and 11% and 13% for C25 and C50 recycled concrete when the NCA was replaced 100% by RBA. In general, the concrete with RCA has better performance than the concrete with RBA. The comparison of the present experimental results with those reported in literature for hardened concrete with either RCA or RBA demonstrates the effectiveness in improving the compressive strength by using the optimal gradation of recycled aggregates.

  13. Evaluating the Carbonation Resistance of Self Compacting Concrete made with Recycled Concrete Aggregates

    Directory of Open Access Journals (Sweden)

    S P Singh

    2016-07-01

    Full Text Available The paper presents the results of an investigation conducted to examine carbonation resistance of Self Compacting Concrete (SCC made with coarse Recycled Concrete Aggregates (RCA. In total, five SCC mixes were prepared by systematically replacing coarse Natural Aggregates (NA by RCA at 0, 25, 50, 75 and 100%. In order to measure the carbonation resistance of SCC made with RCA, accelerated carbonation tests were performed for 4 and 12 weeks of exposure to carbon dioxide. The carbonation resistance has been evaluated after curing periods of 28 and 90 days. In addition to this, the compressive strength of all the mixes was also obtained after 7, 28 and 90 days of curing and ultra-sonic pulse velocity tests (UPV were also conducted. The results indicate that with the increase in the content of RCA as replacement of NA, decrease in the carbonation resistance, compressive strength and UPV was observed for all SCC mixes. It has been observed that the SCC mixes containing low percentages of RCA (i.e. 25% as replacement of NA do not impart detrimental behaviour in the overall performance but higher replacement levels (>50% have been found to deteriorate the performance in terms of carbonation resistance, compressive strength and UPV.

  14. The contribution of nuclear-related technical cooperation to national development

    International Nuclear Information System (INIS)

    Cook, D.

    1988-01-01

    The present situation of nuclear technical assistance and the IAEA's programs are reviewed. The perspectives of the developing and of the developed countries are discussed. Australia's aid administrators have been showing an increasing preference for administering its nuclear technical assistance through the Regional Cooperation Agreement for Asia and the Pacific (RCA), because of its direct benefits to the countries in the region, its flexibility, its emphasis on training, and its cooperative nature. The RCA also benefits from IAEA management and IAEA and United Nations Development Program funding. Two examples of Australia's successful RCA activities are the 1988 radiation protection training course held in Sydney and one of the many individual projects within the 1980-86 RCA hydrology program - the application of radioisotope tracer techniques to locating the seepage areas in the Pedu dam in Kedah State, Malaysia. Australia's experience has shown that project design, successful training of the right people, adequate infrastructure in both donor and recipient countries, and detailed post-project evaluation are the keys to successful project implementation. The RCA has achieved wide recognition as a successful tool in nuclear-related technology transfer

  15. Root Cause Analysis: Learning from Adverse Safety Events.

    Science.gov (United States)

    Brook, Olga R; Kruskal, Jonathan B; Eisenberg, Ronald L; Larson, David B

    2015-10-01

    Serious adverse events continue to occur in clinical practice, despite our best preventive efforts. It is essential that radiologists, both as individuals and as a part of organizations, learn from such events and make appropriate changes to decrease the likelihood that such events will recur. Root cause analysis (RCA) is a process to (a) identify factors that underlie variation in performance or that predispose an event toward undesired outcomes and (b) allow for development of effective strategies to decrease the likelihood of similar adverse events occurring in the future. An RCA process should be performed within the environment of a culture of safety, focusing on underlying system contributors and, in a confidential manner, taking into account the emotional effects on the staff involved. The Joint Commission now requires that a credible RCA be performed within 45 days for all sentinel or major adverse events, emphasizing the need for all radiologists to understand the processes with which an effective RCA can be performed. Several RCA-related tools that have been found to be useful in the radiology setting include the "five whys" approach to determine causation; cause-and-effect, or Ishikawa, diagrams; causal tree mapping; affinity diagrams; and Pareto charts. © RSNA, 2015.

  16. Primer Extension Mutagenesis Powered by Selective Rolling Circle Amplification

    Science.gov (United States)

    Huovinen, Tuomas; Brockmann, Eeva-Christine; Akter, Sultana; Perez-Gamarra, Susan; Ylä-Pelto, Jani; Liu, Yuan; Lamminmäki, Urpo

    2012-01-01

    Primer extension mutagenesis is a popular tool to create libraries for in vitro evolution experiments. Here we describe a further improvement of the method described by T.A. Kunkel using uracil-containing single-stranded DNA as the template for the primer extension by additional uracil-DNA glycosylase treatment and rolling circle amplification (RCA) steps. It is shown that removal of uracil bases from the template leads to selective amplification of the nascently synthesized circular DNA strand carrying the desired mutations by phi29 DNA polymerase. Selective RCA (sRCA) of the DNA heteroduplex formed in Kunkel's mutagenesis increases the mutagenesis efficiency from 50% close to 100% and the number of transformants 300-fold without notable diversity bias. We also observed that both the mutated and the wild-type DNA were present in at least one third of the cells transformed directly with Kunkel's heteroduplex. In contrast, the cells transformed with sRCA product contained only mutated DNA. In sRCA, the complex cell-based selection for the mutant strand is replaced with the more controllable enzyme-based selection and less DNA is needed for library creation. Construction of a gene library of ten billion members is demonstrated with the described method with 240 nanograms of DNA as starting material. PMID:22355397

  17. Damage assessment for seismic response of recycled concrete filled steel tube columns

    Science.gov (United States)

    Huang, Yijie; Xiao, Jianzhuang; Shen, Luming

    2016-09-01

    A model for evaluating structural damage of recycled aggregate concrete filled steel tube (RCFST) columns under seismic effects is proposed in this paper. The proposed model takes the lateral deformation and the effect of repeated cyclic loading into account. Available test results were collected and utilized to calibrate the parameters of the proposed model. A seismic test for six RCFST columns was also performed to validate the proposed damage assessment model. The main test parameters were the recycled coarse aggregate (RCA) replacement percentage and the bond-slip property. The test results indicated that the seismic performance of the RCFST member depends on the RCA contents and their damage index increases as the RCA replacement percentage increases. It is also indicated that the damage degree of RCFST changes with the variation of the RCA replacement percentage. Finally, comparisons between the RCA contents, lateral deformation ratio and damage degree were implemented. It is suggested that an improvement procedure should be implemented in order to compensate for the performance difference between the RCFST and normal concrete filled steel tubes (CFST).

  18. Implementing systems thinking for infection prevention: The cessation of repeated scabies outbreaks in a respiratory care ward.

    Science.gov (United States)

    Chuang, Sheuwen; Howley, Peter P; Lin, Shih-Hua

    2015-05-01

    Root cause analysis (RCA) is often adopted to complement epidemiologic investigation for outbreaks and infection-related adverse events in hospitals; however, RCA has been argued to have limited effectiveness in preventing such events. We describe how an innovative systems analysis approach halted repeated scabies outbreaks, and highlight the importance of systems thinking for outbreaks analysis and sustaining effective infection prevention and control. Following RCA for a third successive outbreak of scabies over a 17-month period in a 60-bed respiratory care ward of a Taiwan hospital, a systems-oriented event analysis (SOEA) model was used to reanalyze the outbreak. Both approaches and the recommendations were compared. No nosocomial scabies have been reported for more than 1975 days since implementation of the SOEA. Previous intervals between seeming eradication and repeat outbreaks following RCA were 270 days and 180 days. Achieving a sustainable positive resolution relied on applying systems thinking and the holistic analysis of the system, not merely looking for root causes of events. To improve the effectiveness of outbreaks analysis and infection control, an emphasis on systems thinking is critical, along with a practical approach to ensure its effective implementation. The SOEA model provides the necessary framework and is a viable complementary approach, or alternative, to RCA. Copyright © 2015 Association for Professionals in Infection Control and Epidemiology, Inc. Published by Elsevier Inc. All rights reserved.

  19. Controlled Microwave Heating Accelerates Rolling Circle Amplification.

    Directory of Open Access Journals (Sweden)

    Takeo Yoshimura

    Full Text Available Rolling circle amplification (RCA generates single-stranded DNAs or RNA, and the diverse applications of this isothermal technique range from the sensitive detection of nucleic acids to analysis of single nucleotide polymorphisms. Microwave chemistry is widely applied to increase reaction rate as well as product yield and purity. The objectives of the present research were to apply microwave heating to RCA and indicate factors that contribute to the microwave selective heating effect. The microwave reaction temperature was strictly controlled using a microwave applicator optimized for enzymatic-scale reactions. Here, we showed that microwave-assisted RCA reactions catalyzed by either of the four thermostable DNA polymerases were accelerated over 4-folds compared with conventional RCA. Furthermore, the temperatures of the individual buffer components were specifically influenced by microwave heating. We concluded that microwave heating accelerated isothermal RCA of DNA because of the differential heating mechanisms of microwaves on the temperatures of reaction components, although the overall reaction temperatures were the same.

  20. Performance of composite sand cement brick containing recycle concrete aggregate and waste polyethylene terephthalate with different mix design ratio

    Science.gov (United States)

    Azmi, N. B.; Khalid, F. S.; Irwan, J. M.; Mazenan, P. N.; Zahir, Z.; Shahidan, S.

    2018-04-01

    This study is focuses to the performance of composite sand cement brick containing recycle concrete aggregate and waste polyethylene terephthalate. The objective is to determine the mechanical properties such as compressive strength and water absorption of composite brick containing recycled concrete aggregate and polyethylene terephthalate waste and to determine the optimum mix ratio of bricks containing recycled concrete aggregate and polyethylene terephthalate waste. The bricks specimens were prepared by using 100% natural sand, they were then replaced by RCA at 25%, 50% and 75% with proportions of PET consists of 1.0%, 1.5%, 2.0% and 2.5% by weight of natural sand. Based on the results of compressive strength, it indicates that the replacement of RCA shows an increasing strength as the strength starts to increase from 25% to 50% for both mix design ratio. The strength for RCA 75% volume of replacement started to decrease as the volume of PET increase. However, the result of water absorption with 50% RCA and 1.0% PET show less permeable compared to control brick at both mix design ratio. Thus, one would expect the density of brick decrease and the water absorption to increase as the RCA and PET content is increased.

  1. Industrial technology transfer in Asia and the Pacific

    International Nuclear Information System (INIS)

    Fowler, E.E.

    1982-01-01

    For ten years the Regional Co-operative Agreement for research, development and training related to nuclear science and technology (RCA) has brought together work of the IAEA and Member States in Asia and the Pacific. Current RCA projects concern health care, food and agriculture, hydrology, and industry - areas of great importance to participating Member States. Each of the nine projects emphasizes the use of well-developed nuclear technologies to improve the standard of living in the region. Applied research and development in areas of common interest to RCA Member States are promoted through these co-operative projects. Successful results are shared among participants. The industrial project, funded by the UNDP and executed by the IAEA, aims to expand and accelerate the uses of isotopes and radiation technology in five fields of industrial application. The industrial project is currently the largest project under the RCA: almost all parties to the agreement participate. Planned expenditures for the seven-year project total about US $12 500 000 (including UNDP funds and Government contributions). Like other projects under the RCA, the industrial project will serve the pressing economic and social needs of the Asia and Pacific region. It can serve as a model to be followed by other regions of the world

  2. JOINT ADVISORY APPEALS BOARD

    CERN Multimedia

    Personnel Division

    1999-01-01

    The Joint Advisory Appeals Board was convened to examine the appeal lodged by Mr Joào Bento with regard to residential category. As the appellant has not objected, the recommendations of the Board and the final decision of the Director-General are brought to the notice of the personnel in accordance with Article RÊVIÊ1.20 of the Staff Regulations.The relevant documents will therefore be posted on the notice boards of the Administration Building (N¡ 60) from 29 October to 12 November 1999.Personnel DivisionTel. 74128

  3. Fosforitos do Grupo Bambuí na região de Campos Belos (GO)/ Arraias (TO), na borda oeste do Cráton São Francisco

    OpenAIRE

    Monteiro, Cimara Francisca

    2009-01-01

    Os depósitos de fosfato sedimentar da região de Campos Belos (GO) e Arraias (TO) compreendem ate o momento três depósitos de volume reduzido, mas com teores elevados, superiores a 24% P2O5, denominados: São Bento, Coite 1 e Coite 2. Os fosforitos e siltitos fosfatados encontrados na regiao estao inseridos na porcao basal da Formação Sete Lagoas, pertencente ao Grupo Bambui, de idade Neoproterozoica. O Grupo Bambui integra a porção oriental da Faixa de Dobramentos Brasília e tambem compõe ampl...

  4. Seguridad y protección de información de la bahía interior de puno del lago Titicaca

    OpenAIRE

    Canqui Flores, Bernabé

    2001-01-01

    El presente estudio se ha ejecutado en la provincia de Puno, el conocimiento de aplicaciones informáticas en el campo de la Biología, de información cualitativa y cuantitativa, se realiza para la creación de software aplicativo, utilizando lenguajes de alto nivel, para ofrecer seguridad, conftabilidad y protección de información de la Bahía Interior de Puno del Lago Titicaca. Esta investigación se desarrolló con información de Bentos en tres épocas climáticas (Junio-Julio, Agosto-Setiembre y ...

  5. ENTRE RETRATOS E MEMÓRIAS: AS ILUSTRAÇÕES DE POTY EM DOM CASMURRO

    Directory of Open Access Journals (Sweden)

    Cilene Margarete Pereira

    2010-01-01

    Full Text Available En la edición de Dom Casmurro (colección "Clásicos Brasileños", los grabados del artista Poty revelan, en parte, adhesión al discurso del narrador, puntuando la imagen dudosa de Capitu. Sin embargo, en al menos dos ilustraciones, Poty señala otra perspectiva, capaz de descubrir la visión borrosa y amargado el narrador Bento Santiago en relación con la amiga de la infancia.

  6. Uma padre na aldeia global : nova evangelização e novas tecnologias de informação e comunicação

    OpenAIRE

    Aguiar, Américo Manuel Alves

    2012-01-01

    Nesta dissertação, revemos os últimos cem anos de pronunciamentos dos sucessores de Pedro, do Papa Leão XIII, ao Papa Bento XVI, atestando a atenção e interesse com que a igreja católica sempre olhou para as potencialidades oferecidas pelas novas tecnologias de informação e de comunicação. Olhamos de um ponto de vista comunicacional para a urgência da Nova Evangelização pronunciada pelo Papa João Paulo II, dando continuidade ao já expresso pelo Papa Paulo VI e pelo próprio II ...

  7. Mercúrio total em cabelos: uma contribuição para se avaliar o nível de exposição em Poconé, Mato Grosso, Brasil Total mercury in hair: a contribution to the evaluation of mercury exposure levels in Poconé, Mato Grosso, Brazil

    Directory of Open Access Journals (Sweden)

    Flávia Nogueira

    1997-10-01

    Full Text Available Ocorrem na Bacia do Rio Bento Gomes (MT, às margens do Pantanal Mato-grossense, cerca de sessenta garimpos de ouro, onde o mercúrio é utilizado de forma intensiva nos processos de produção, através da formação de amálgamas que facilitam a aglutinação de partículas finas. A queima do amálgama nem sempre é feita em sistemas fechados de recuperação, havendo, portanto, perda de vapor para a atmosfera. Este estudo traz resultados de análises de mercúrio total nos cabelos de quatro grupos de voluntários que vivem em Poconé (MT, e faz uma caracterização geral do ambiente no que se refere à presença do metal na água e no sedimento do Rio Bento Gomes. Um equipamento de detecção por fluorescência foi usado para a determinação das concentrações, e os resultados indicam que os valores são mais baixos do que os de outras populações de áreas de garimpo no Brasil. Indicam também que a via ocupacional parece ser a mais eficiente rota potencial de contaminação da população por mercúrio.There are some 60 gold-mining sites in the Bento Gomes River basin (Mato Grosso, at the border of the Mato Grosso Pantanal (Swamp, where mercury is used to agglutinate fine gold particles through amalgamation. During burning of the amalgam to release the gold, mercury vapor is lost to the atmosphere, since closed systems for mercury recovery are not always used. This study shows the results of total mercury analysis in hair from four volunteer groups living in Poconé, Mato Grosso, and presents a general environmental description pertaining to the presence of mercury in water and sediments from the Bento Gomes River. Atomic fluorescence was used for measuring mercury concentrations. The results were lower than for other populations from gold-mining areas in Brazil.

  8. Casa Camelo - quando a casa se adéqua ao meio: proposta arquitetônica para residência unifamiliar de alto padrão levando em consideração aspectos ambientais sustentáveis de gestão de água, energia e condicionantes bioclimáticas

    OpenAIRE

    Macedo, André Luiz Gomes de

    2016-01-01

    Esse trabalho envolve pesquisas recentes que levantam prescrições técnicas para se projetar residências unifamiliares de alto padrão, suprindo uma lacuna sustentável específica em se absorver, compreender e inserir alguns desses conceitos complementares às formas tradicionais de se habitar, aqui destacado como algo que sucedeu o ato de projetar e construir. O surgimento de uma demanda de um projeto a ser confeccionado na cidade de Serra de São Bento, a 130 km de Natal-RN trouxe...

  9. A Factorial Design Approach to Analyse the Effect of Coarse Recycled Concrete Aggregates on the Properties of Hot Mix Asphalt

    Science.gov (United States)

    Tanty, Kiranbala; Mukharjee, Bibhuti Bhusan; Das, Sudhanshu Shekhar

    2018-06-01

    The present study investigates the effect of replacement of coarse fraction of natural aggregates by recycled concrete aggregates on the properties of hot mix asphalt (HMA) using general factorial design approach. For this two factors i.e. recycled coarse aggregates percentage [RCA (%)] and bitumen content percentage [BC (%)] are considered. Tests have been carried out on the HMA type bituminous concrete, prepared with varying RCA (%) and BC (%). Analysis of variance has been performed on the experimental data to determine the effect of the chosen factors on various parameters such as stability, flow, air void, void mineral aggregate, void filled with bitumen and bulk density. The study depicts that RCA (%) and BC (%) have significant effect on the selected responses as p value is less than the chosen significance level. In addition to above, the outcomes of the statistical analysis indicate that interaction between factors have significant effects on void mineral aggregate and bulk density of bituminous concrete.

  10. Influence of a low calcium and phosphorus diet on the anabolic effect of human parathyroid hormone (1-38) in female rats

    DEFF Research Database (Denmark)

    Steiner, P.D.; Forrer, R.; Kneissel, Michaela

    2001-01-01

    Parathyroid hormone (PTH) or synthetic N-terminal PTH fragments administered intermittently have been established as anabolic agents in animal and human bones. In the present study, the influence of a low calcium diet on the anabolic effect of human PTH(1-38) [hPTH(1-38)] was investigated. Forty......-eight 10-week-old female Sprague-Dawley rats were randomly assigned to a diet with a low calcium content (LCa) or a diet with the recommended amount of calcium (RCa). After an adaptation period of 15 days, the rats were randomly assigned to hPTH(1-38) treatment (+LCa/+RCa) or vehicle only (-LCa....../-RCa) for an additional 14 days. Total bone mineral density (BMD) values of several bones were determined using quantitative computed tomography and from ratios of ash weight to volume. Biomechanical competence of the fourth lumbar vertebrae and of the right femora was assessed. An anabolic effect could be detected...

  11. Rotastenting in an anomalously arising right coronary artery after an ugly dissection

    Directory of Open Access Journals (Sweden)

    Ashwin B. Mehta

    2013-07-01

    Full Text Available Rotational atherectomy is contraindicated in dissected coronary arteries since it can lead to progression of the dissection or perforation. In our case, the right coronary artery (RCA arose anomalously from the left coronary sinus. The lesion in the RCA was an undilatable calcified one. There was a dissection in the RCA due to high pressure balloon dilatation. Since the patient was hemodynamically unstable and there were no options besides rotablation, we proceeded with caution. Rotablation and stenting were successfully done. Our case report highlights the importance of the need for good guide catheter support even in the presence of anomalously arising arteries and the rotablation option for unyielding calcified coronary lesions, even in the setting of a dissection.

  12. [Image fusion of gated-SPECT and CT angiography in coronary artery disease. Importance of anatomic-functional correlation].

    Science.gov (United States)

    Nazarena Pizzi, M; Aguadé Bruix, S; Cuéllar Calabria, H; Aliaga, V; Candell Riera, J

    2010-01-01

    A 77-year old patient was admitted for acute coronary syndrome without ST elevation. His risk was stratified using the myocardial perfusion gated SPECT, mild inferior ischemia being observed. Thus, medical therapy was optimized and the patient was discharged. He continued with exertional dyspnea so a coronary CT angiography was performed. It revealed severe lesions in the proximal RCA. SPECT-CT fusion images correlated the myocardial perfusion defect with a posterior descending artery from the RCA, in a co-dominant coronary area. Subsequently, cardiac catheterism was indicated for his treatment. The current use of image fusion studies is limited to patients in whom it is difficult to attribute a perfusion defect to a specific coronary artery. In our patient, the fusion images helped to distinguish between the RCA and the circumflex artery as the culprit artery of ischemia. Copyright © 2010 Elsevier España, S.L. y SEMNIM. All rights reserved.

  13. Characterization of Rubisco activase from thermally contrasting genotypes of Acer rubrum (Aceraceae).

    Science.gov (United States)

    Weston, David J; Bauerle, William L; Swire-Clark, Ginger A; Moore, Brandon D; Baird, Wm Vance

    2007-06-01

    The lability of Rubisco activase function is thought to have a major role in the decline of leaf photosynthesis under moderate heat (RCA1 and RCA2 proteins increased modestly in FL plants under warmer temperature, while only RCA2 protein increased in MN plants. Rubisco large subunit (RbsL) protein abundance was relatively unaffected in either genotype by temperature. These results support the idea that Rubisco activase, particularly the ratio of Rubisco activase to Rubisco, may play a role in the photosynthetic heat acclimation in A. rubrum and may have adaptive significance. This mechanism alone is not likely to entirely explain the thermotolerance in the FL genotype, and future research on adaptive mechanisms to high temperatures should consider activase function in a multipathway framework.

  14. A Factorial Design Approach to Analyse the Effect of Coarse Recycled Concrete Aggregates on the Properties of Hot Mix Asphalt

    Science.gov (United States)

    Tanty, Kiranbala; Mukharjee, Bibhuti Bhusan; Das, Sudhanshu Shekhar

    2018-02-01

    The present study investigates the effect of replacement of coarse fraction of natural aggregates by recycled concrete aggregates on the properties of hot mix asphalt (HMA) using general factorial design approach. For this two factors i.e. recycled coarse aggregates percentage [RCA (%)] and bitumen content percentage [BC (%)] are considered. Tests have been carried out on the HMA type bituminous concrete, prepared with varying RCA (%) and BC (%). Analysis of variance has been performed on the experimental data to determine the effect of the chosen factors on various parameters such as stability, flow, air void, void mineral aggregate, void filled with bitumen and bulk density. The study depicts that RCA (%) and BC (%) have significant effect on the selected responses as p value is less than the chosen significance level. In addition to above, the outcomes of the statistical analysis indicate that interaction between factors have significant effects on void mineral aggregate and bulk density of bituminous concrete.

  15. Reliability and utility of citizen science reef monitoring data collected by Reef Check Australia, 2002-2015.

    Science.gov (United States)

    Done, Terence; Roelfsema, Chris; Harvey, Andrew; Schuller, Laura; Hill, Jocelyn; Schläppy, Marie-Lise; Lea, Alexandra; Bauer-Civiello, Anne; Loder, Jennifer

    2017-04-15

    Reef Check Australia (RCA) has collected data on benthic composition and cover at >70 sites along >1000km of Australia's Queensland coast from 2002 to 2015. This paper quantifies the accuracy, precision and power of RCA benthic composition data, to guide its application and interpretation. A simulation study established that the inherent accuracy of the Reef Check point sampling protocol is high (<±7% error absolute), in the range of estimates of benthic cover from 1% to 50%. A field study at three reef sites indicated that, despite minor observer- and deployment-related biases, the protocol does reliably document moderate ecological changes in coral communities. The error analyses were then used to guide the interpretation of inter-annual variability and long term trends at three study sites in RCA's major 2002-2015 data series for the Queensland coast. Copyright © 2017 Elsevier Ltd. All rights reserved.

  16. Unusually Looped and Muzzled Branches of Right Coronary Artery

    Directory of Open Access Journals (Sweden)

    Anitha Guru

    2017-01-01

    Full Text Available Coronary artery disease (CAD is the major cause of death in developed countries as it accounts on an average for 1 of every 5 deaths. Morphological variations of coronary arterial system is one of the causative factor for CAD. Anatomical knowledge of all possible variant patterns of coronary arterial system is imperative in the diagnostic and therapeutic approach of CAD. We report here a rare branching pattern of right coronary artery (RCA. The origin of RCA was normal but the course and branching pattern of it were atypical. RCA was not occupying its usual position in atrioventricular (coronary sulcus and its course was incomplete. It gave a ventricular branch to right ventricle, which presented an unusual looping pattern. It terminated as right marginal artery following its muzzled appearance within the musculature of the ventricle.

  17. Revealed Comparative Advantage and the Alternatives as Measures of International Specialization

    DEFF Research Database (Denmark)

    Laursen, Keld

    2015-01-01

    This paper provides an analysis of Balassa's 'revealed comparative advantage' (RCA). It shows that when using RCA, it should be adjusted such that it becomes symmetric around its neutral value. The proposed adjusted index is called 'revealed symmetric comparative advantage' (RSCA). The theoretica...... Balance, Chi Square, and Bowen's Net Trade Index. The result of the analysis is that RSCA-on balance-is the best measure of comparative advantage....... discussion focuses on the properties of RSCA and empirical evidence, based on the Jarque-Bera test for normality of the regression error terms, using both the RCA and RSCA indices. We compare RSCA to other measures of international trade specialization including the Michaely index, the Contribution to Trade...

  18. Digital quantification of rolling circle amplified single DNA molecules in a resistive pulse sensing nanopore.

    Science.gov (United States)

    Kühnemund, M; Nilsson, M

    2015-05-15

    Novel portable, sensitive and selective DNA sensor methods for bio-sensing applications are required that can rival conventionally used non-portable and expensive fluorescence-based sensors. In this paper, rolling circle amplification (RCA) products are detected in solution and on magnetic particles using a resistive pulse sensing (RPS) nanopore. Low amounts of DNA molecules are detected by padlock probes which are circularized in a strictly target dependent ligation reaction. The DNA-padlock probe-complex is captured on magnetic particles by sequence specific capture oligonucleotides and amplified by a short RCA. Subsequent RPS analysis is used to identify individual particles with single attached RCA products from blank particles. This proof of concept opens up for a novel non-fluorescent digital DNA quantification method that can have many applications in bio-sensing and diagnostic approaches. Copyright © 2014 Elsevier B.V. All rights reserved.

  19. The role and activity of the IAEA in the field of isotope use

    International Nuclear Information System (INIS)

    Kakihana, H.

    1980-01-01

    The Regional Cooperative Agreement (RCA) in Asia by IAEA entered into force in June, 1972, based on the period of every 5 years with the participation of Australia, India, Indonesia, Japan, Republic of Korea, Malaysia, Pakistan, Phillippine, Singapore and Thailand. The RCA aims to direct its technological efforts of using isotopes and radiation to the areas of highest regional interests, i.e. food and agriculture, health care, water resource management, environmental control and industrial development, along with upgrading the infrastructure to keep pace with technological advancements. The activities of the RCA in these fields are described as follows: food processing with ionizing radiation and the improvement of protein supplies, environment, hydrology and sedimentology, neutron scattering and nuclear instrument maintenance, UNDP regional project for industrial isotope and radiation applications. (J.P.N.)

  20. Identifying and Overcoming Barriers to Effective Consideration of Human and Organisational Factors in Event Analysis and Root Cause Analysis. Workshop Proceedings, September 21-22, 2009, Paris, France

    International Nuclear Information System (INIS)

    2011-01-01

    Nuclear licensees must have effective processes for learning from operating experience in order to manage safety, secure continuous improvement and defend against the potential for repeat events. These processes include root cause analysis (RCA) to identify the underlying causes of events and mechanisms to learn from these analyses and to implement improvements. Correctly identifying and correcting the causes of events will allow lessons to be learned and shared with others in the industry. The treatment of Human and Organisational Factors (HOF) in RCA is of special interest to WGHOF. It is estimated that approximately 60-80% of events in the nuclear industry can be attributed to human and organisational factors. Although the importance of correctly identifying the HOF causes is understood, there is still a tendency for the analysis to focus solely on the technical issues of the event. The history of prominent events across the major hazards sector shows that HOF lessons often fail to be learned. A NEA/CSNI special experts meeting entitled 'Identification of Barriers to Analyzing and Identifying Human and Organisational Factors in Root Cause Analysis' was held at the NEA Headquarters in Paris, France on September 21-22, 2009. A total of 17 participants from 10 countries representing licensee organisations, regulators, international organisations and an independent consultant attended the meeting. The meeting was structured to allow for small group discussions during which a number of themes were explored, followed by plenary discussion. There were also four papers presented which complemented the discussion themes. As set out in the objectives of this work, the participants identified barriers to the effective treatment of HOF in RCA and recommendations to mitigate the effects of these barriers. Many of the barriers and recommendations identified relate to the RCA process in general, not specifically to the treatment of HOF in the RCA process. This is logical, for

  1. Impact of aging on leaching characteristics of recycled concrete aggregate.

    Science.gov (United States)

    Abbaspour, Aiyoub; Tanyu, Burak F; Cetin, Bora

    2016-10-01

    The focus of this study was to evaluate the effects of stockpiling (aging) on leaching of elements in recycled concrete aggregate (RCA) that may contribute to tufaceous constituent formation. Speciation and leaching controlling mechanisms of these elements were identified via geochemical modeling. The effects of stockpiling were simulated by comparing freshly produced RCA with RCA aged as part of this study for 1 year both in the laboratory and in the field. Leachate samples were generated following batch water leach test (WLT) and US Geological Survey leach test (USGSLT) methods. USGSLTs were conducted both on the laboratory and field samples while WLT was only conducted on laboratory samples. During the laboratory aging, it is observed that the carbonate content of RCA, measured as calcite equivalent, increased 20 % (i.e., from ∼100 to 120 mg/g) within a year time frame. The leachate extracted from RCA showed minor changes in pH and more significant decreases in electrical conductivity (i.e., ∼300 to 100 μS/cm). A comparison between laboratory and field samples revealed that the RCA aged much slower in the field than in the laboratory within a year. Comparisons between two leach extraction methods on the laboratory conditions showed that the total leached concentrations (TLCs) of most of the constituents from USGSLT were appreciably lower than the ones measured via WLT method. The results of geochemical modeling analyses showed that Al, Si, Fe, Ca, Mg, and Cu exist in their oxidized forms as Al 3+ , Fe 3+ , Si 4+ , Ca 2+ , Mg 2+ , and Cu 2+ and results revealed that these elements are primarily controlled by the solubility of gibbsite, hematite, silica gel, calcite, magnesite, and tenorite solid phases, respectively. One of the significant findings of the study was to identify the changes in leaching behavior of Ca, Si, Mg, Al, Fe, and Cu due to carbonation.

  2. Quality assessment of atmospheric surface fields over the Baltic Sea from an ensemble of regional climate model simulations with respect to ocean dynamics

    Directory of Open Access Journals (Sweden)

    H. E. Markus Meier

    2011-05-01

    Full Text Available Climate model results for the Baltic Sea region from an ensemble of eight simulations using the Rossby Centre Atmosphere model version 3 (RCA3 driven with lateral boundary data from global climate models (GCMs are compared with results from a downscaled ERA40 simulation and gridded observations from 1980-2006. The results showed that data from RCA3 scenario simulations should not be used as forcing for Baltic Sea models in climate change impact studies because biases of the control climate significantly affect the simulated changes of future projections. For instance, biases of the sea ice cover in RCA3 in the present climate affect the sensitivity of the model's response to changing climate due to the ice-albedo feedback. From the large ensemble of available RCA3 scenario simulations two GCMs with good performance in downscaling experiments during the control period 1980-2006 were selected. In this study, only the quality of atmospheric surface fields over the Baltic Sea was chosen as a selection criterion. For the greenhouse gas emission scenario A1B two transient simulations for 1961-2100 driven by these two GCMs were performed using the regional, fully coupled atmosphere-ice-ocean model RCAO. It was shown that RCAO has the potential to improve the results in downscaling experiments driven by GCMs considerably, because sea surface temperatures and sea ice concentrations are calculated more realistically with RCAO than when RCA3 has been forced with surface boundary data from GCMs. For instance, the seasonal 2 m air temperature cycle is closer to observations in RCAO than in RCA3 downscaling simulations. However, the parameterizations of air-sea fluxes in RCAO need to be improved.

  3. Effects of a 3D segmental prosthetic system for tricuspid valve annulus remodelling on the right coronary artery: a human cadaveric coronary angiography study.

    Science.gov (United States)

    Riki-Marishani, Mohsen; Gholoobi, Arash; Sazegar, Ghasem; Aazami, Mathias H; Hedjazi, Aria; Sajjadian, Maryam; Ebrahimi, Mahmoud; Aghaii-Zade Torabi, Ahmad

    2017-09-01

    A prosthetic system to repair secondary tricuspid valve regurgitation was developed. The conceptual engineering of the current device is based on 3D segmental remodelling of the tricuspid valve annulus in lieu of reductive annuloplasty. This study was designed to investigate the operational safety of the current prosthetic system with regard to the anatomical integrity of the right coronary artery (RCA) in fresh cadaveric human hearts. During the study period, from January to April 2016, the current prosthetic system was implanted on the tricuspid valve annulus in fresh cadaveric human hearts that met the study's inclusion criteria. The prepared specimens were investigated via selective coronary angiography of the RCA in the catheterization laboratory. The RCA angiographic anatomies were categorized as normal, distorted, kinked or occluded. Sixteen specimens underwent implantation of the current prosthetic system. The mean age of the cadaveric human hearts was 43.24 ± 15.79 years, with vehicle accident being the primary cause of death (59%). A dominant RCA was noticed in 62.5% of the specimens. None of the specimens displayed any injury, distortion, kinking or occlusion in the RCA due to the implantation of the prostheses. In light of the results of the present study, undertaken on fresh cadaveric human heart specimens, the current segmental prosthetic system for 3D remodelling of the tricuspid valve annulus seems to be safe vis-à-vis the anatomical integrity of the RCA. Further in vivo studies are needed to investigate the functional features of the current prosthetic system with a view to addressing the complex pathophysiology of secondary tricuspid valve regurgitation. © The Author 2017. Published by Oxford University Press on behalf of the European Association for Cardio-Thoracic Surgery. All rights reserved.

  4. Linear reversible second-order cellular automata and their first-order matrix equivalents

    International Nuclear Information System (INIS)

    Macfarlane, A J

    2004-01-01

    Linear or one-dimensional reversible second-order cellular automata, exemplified by three cases named as RCA1-3, are introduced. Displays of their evolution in discrete time steps, t=0, 1, 2, ..., from their simplest initial states and on the basis of updating rules in modulo 2 arithmetic, are presented. In these, shaded and unshaded squares denote cells whose cell variables are equal to one and zero respectively. This paper is devoted to finding general formulas for, and explicit numerical evaluations of, the weights N(t) of the states or configurations of RCA1-3, i.e. the total number of shaded cells in tth line of their displays. This is achieved by means of the replacement of RCA1-3 by the equivalent linear first-order matrix automata MCA1-3, for which the cell variables are 2x2 matrices, instead of just numbers (element of Z 2 ) as for RCA1-3. MCA1-3 are tractable because it has been possible to generalize to them the heavy duty methods already well-developed for ordinary first-order cellular automata like those of Wolfram's Rules 90 and 150. While the automata MCA1-3 are thought to be of genuine interest in their own right, with untapped further mathematical potential, their treatment has been applied here to expediting derivation of a large body of general and explicit results for N(t) for RCA1-3. Amongst explicit results obtained are formulas also for each of RCA1-3 for the total weight of the configurations of the first 2 M times, M=0, 1, 2, ..

  5. Real-time monitoring of mycobacterium genomic DNA with target-primed rolling circle amplification by a Au nanoparticle-embedded SPR biosensor.

    Science.gov (United States)

    Xiang, Yang; Zhu, Xiaoyan; Huang, Qing; Zheng, Junsong; Fu, Weiling

    2015-04-15

    In this study, we developed a surface plasmon resonance (SPR) DNA biosensor array based on target-primed rolling circle amplification (RCA) for isothermal and rapid detection of two pathogenic mycobacteria, Mycobacterium tuberculosis complex (MTBC) and Mycobacterium avium complex (MAC).The species-specific padlock probe (PLP) was designed to target the sequence in 16S-23S rRNA gene internal transcribed spacer (ITS). After ligation, the circularized PLP could be primed by the target sequence to initial RCA. The RCA performed simultaneously with the cleavage reaction to produce small fragments of single strand DNA which immediately hybridized with the probe immobilized on the sensor chip without denaturation. This process caused SPR angle changes on the chip surface, which made the detection for analysis from the solution achievable, and dynamic real-time RCA monitoring of mycobacterium possible. Besides, Au nanoparticles (AuNPs) were directly assembled onto the surface of the sensor chip via hexanedithiol (HDT) for the enhancement of sensitivity as a label-free detection system. Experimental results show that the signal enhancement by the target-primed RCA together with AuNPs-embedded surface caused at least10-fold increased sensitivity as compared with conventional RCA on bare SPR chip method. Within 40min amplification duration as low as 20amol of synthetic targets and 10(4)CFUmL(-1) of genomic DNA from clinical samples can be detected. The proposed method not only provides a simple design idea for liquid-phase amplification monitoring, but also apply it in clinical pathogen detection, which holds great promise in ultrasensitive bioassay in the future. Copyright © 2014. Published by Elsevier B.V.

  6. Right ventricular function after acute myocardial infarction: dependence upon infarct related coronary artery

    International Nuclear Information System (INIS)

    Cho, Ihn Ho; Chun, Kyung A; Won, Kyu Chang; Lee, Hyung Woo; Hong, Geu Ru; Park, Jong Seon; Shin, Dong Gu; Kim, Young Jo; Shim, Bong Sub

    2004-01-01

    We studied to know the relation between right ventricular function and infarct-related artery after acute myocardial infarction. The right and left ventricular function after a first myocardial infarction was assessed ECG-gated blood pool single photon emission computed tomography (GBPS) algorithms (Cedars-Sinai Medical Center, Los Angels, Calif) (12 after LAD related infarction (group 1) and 15 after RCA related infarction (group 2)). The left ventricular ejection fraction, end-diastolic volume and end-systolic volume did not differ significantly between two groups( group 1 vs 2 :LVEF 50.8% vs 55.1%. LVEDV=73.2 vs 79.7 ml, LVESV=38 vs 44 ml : P>0.05), but right ventricular ejection fraction, end-diastolic volume and end-systolic volume were significantly different after anterior myocardial infarction between two groups( group 1 vs 2 : RVEF=57.3% vs 46.3%. RVEDV=56.4 vs 95.1 ml, RVESV=25.6 vs 54.6ml : P<0.05). There was evidence of right ventricular dilatation in the group with RCA related infarction. Six with inferior infarction had abnormal right ventricular ejection fractions (< 40%). The relation between right and left ventricular ejection fractions was markedly different in the two groups. In the group with RCA related infarction there was a significant linear relation between right and left ventricular ejection fraction(R=0.5). Whereas in the group with LAD related infarction there was not (R=-0.3). Thus right ventricular dysfunction commonly occurs after RCA related infarction. Right ventricular impairment is related after RCA related infarction, but are independent after LAD related infarction. Finally, the different effects of LAD and RCA related infarction on right ventricular function may be explained by site of the myocardial wall involvement after infarction

  7. Arctic climate change in an ensemble of regional CORDEX simulations

    Directory of Open Access Journals (Sweden)

    Torben Koenigk

    2015-03-01

    Full Text Available Fifth phase Climate Model Intercomparison Project historical and scenario simulations from four global climate models (GCMs using the Representative Concentration Pathways greenhouse gas concentration trajectories RCP4.5 and RCP8.5 are downscaled over the Arctic with the regional Rossby Centre Atmosphere model (RCA. The regional model simulations largely reflect the circulation bias patterns of the driving global models in the historical period, indicating the importance of lateral and lower boundary conditions. However, local differences occur as a reduced winter 2-m air temperature bias over the Arctic Ocean and increased cold biases over land areas in RCA. The projected changes are dominated by a strong warming in the Arctic, exceeding 15°K in autumn and winter over the Arctic Ocean in RCP8.5, strongly increased precipitation and reduced sea-level pressure. Near-surface temperature and precipitation are linearly related in the Arctic. The wintertime inversion strength is reduced, leading to a less stable stratification of the Arctic atmosphere. The diurnal temperature range is reduced in all seasons. The large-scale change patterns are dominated by the surface and lateral boundary conditions so future response is similar in RCA and the driving global models. However, the warming over the Arctic Ocean is smaller in RCA; the warming over land is larger in winter and spring but smaller in summer. The future response of winter cloud cover is opposite in RCA and the GCMs. Precipitation changes in RCA are much larger during summer than in the global models and more small-scale change patterns occur.

  8. Evaluation of the environmental, material, and structural performance of recycled aggregate concrete

    Science.gov (United States)

    Michaud, Katherine Sarah

    Concrete is the most commonly used building material in the construction industry, and contributes to 52% of construction and demolition waste in Canada. Recycled concrete aggregate (RCA) is one way to reduce this impact. To evaluate the performance of coarse and granular (fine and coarse) RCA in structural concrete applications, four studies were performed: an environmental assessment, a material testing program, a shear performance study, and a flexural performance study. To determine the environmental benefits of recycled aggregate concrete (RAC), three case studies were investigated using different populations and proximities to city centres. Environmental modelling suggested that RCA replacement could result in energy savings and greenhouse gas emission reductions, especially in remote areas. Tests were performed to determine if the volumetric replacement of up to 30% coarse RCA and 20% granular RCA is suitable for structural concrete applications in Canada. Fresh, hardened, and durability properties were evaluated. All five (5) of the RCA mixes showed equivalent material performance to the control mixes and met the requirements for a structural concrete mix. The five (5) RAC mixes were also used in structural testing. One-way reinforced concrete slab specimens were tested to failure to evaluate the shear and flexural performance of the RAC members. Peak capacities of and crack formation within each member were analyzed to evaluate the performance of RAC compared to conventional concrete. The shear capacity of specimens made from four (4) of the five (5) RAC mixtures was higher or equivalent to the control specimens. Specimens of the concrete mixture containing the highest content of recycled aggregate, 20% volumetric replacement of granular RCA, had shear capacities 14.1% lower, and exhibited cracking at lower loads than the control. The average flexural capacities of all RAC specimens were within 3.7% of the control specimens. Results from this research

  9. An Analysis of Adverse Events in the Rehabilitation Department: Using the Veterans Affairs Root Cause Analysis System.

    Science.gov (United States)

    Hagley, Gregory W; Mills, Peter D; Shiner, Brian; Hemphill, Robin R

    2018-04-01

    Root cause analyses (RCA) are often completed in health care settings to determine causes of adverse events (AEs). RCAs result in action plans designed to mitigate future patient harm. National reviews of RCA reports have assessed the safety of numerous health care settings and suggested opportunities for improvement. However, few studies have assessed the safety of receiving care from physical therapists, occupational therapists, or speech and language pathology pathologists. The objective of this study was to determine the types of AEs, root causes, and action plans for risk mitigation that exist within the disciplines of rehabilitation medicine. This study is a retrospective, cross-sectional review. A national search of the Veterans Health Administration RCA database was conducted to identify reports describing AEs associated with physical therapy, occupational therapy, or speech and language pathology services between 2009 and May 2016. Twenty-five reports met the inclusion requirements. The reports were classified by the event type, root cause, action plans, and strength of action plans. Delays in care (32.0%) and falls (28.0%) were the most common type of AE. Three AEs resulted in death. RCA teams identified deficits regarding policy and procedures as the most common root cause. Eighty-eight percent of RCA reports included strong or intermediate action plans to mitigate risk. Strong action plans included standardizing emergency terminology and implementing a dedicated line to call for an emergency response. These data are self-reported and only AEs that are scored as a safety assessment code 3 in the system receive a full RCA, so there are likely AEs that were not captured in this study. In addition, the RCA reports are deidentified and so do not include all patient characteristics. As the Veterans Health Administration system services mostly men, the data might not generalize to non-Veterans Health Administration systems with a different patient mix. Care

  10. Dew inspired breathing-based detection of genetic point mutation visualized by naked eye

    Science.gov (United States)

    Xie, Liping; Wang, Tongzhou; Huang, Tianqi; Hou, Wei; Huang, Guoliang; Du, Yanan

    2014-09-01

    A novel label-free method based on breathing-induced vapor condensation was developed for detection of genetic point mutation. The dew-inspired detection was realized by integration of target-induced DNA ligation with rolling circle amplification (RCA). The vapor condensation induced by breathing transduced the RCA-amplified variances in DNA contents into visible contrast. The image could be recorded by a cell phone for further or even remote analysis. This green assay offers a naked-eye-reading method potentially applied for point-of-care liver cancer diagnosis in resource-limited regions.

  11. The use of 2N3055 transistor as photosensory in solarymeter

    International Nuclear Information System (INIS)

    Bintoro; Sastroamidjojo, M.S.A.

    1981-01-01

    The characteristics of 2N3055 type transistor used for solarymeters sensor. It can be seen that transistor sensor has more response time. The response to against arrival solar intensity is linear. It can be used for solarymeter sensor after calibrated with pyranometer reference, but not so sensitive for 500 nanometer wavelength. It can be concluded that 2N3055 transistor made by Motrola than the made by R.C.A. because the 2N3055 transistor is more wide and more accurate than the R.C.A. transistor. (author tr.)

  12. Sensitive Blu-ray detection of clustered rolling circle products for molecular Diagnostics

    DEFF Research Database (Denmark)

    Ahlford, Annika; Donolato, Marco; Antunes, Paula Soares Martins

    2014-01-01

    In this paper we present a method for low cost and rapid sensing of nucleic acids (NA) for infectious diagnostics, where isothermal rolling circle amplification (RCA) products, specifically generated by the presence of the human pathogen Pseudomonas aeruginosa (PA), are bound to magnetic nanopart......In this paper we present a method for low cost and rapid sensing of nucleic acids (NA) for infectious diagnostics, where isothermal rolling circle amplification (RCA) products, specifically generated by the presence of the human pathogen Pseudomonas aeruginosa (PA), are bound to magnetic...

  13. Improved Focusing Method for 3-D Imaging using Row–Column-Addressed 2-D Arrays

    DEFF Research Database (Denmark)

    Bouzari, Hamed; Engholm, Mathias; Stuart, Matthias Bo

    2017-01-01

    A row–column-addressed (RCA) 2-D array can be interpreted as two orthogonal 1-D arrays. By transmitting with row elements and receiving the echoes through column elements or vice versa, a rectilinear volume in front of the array can be beamformed. Since the transmit and receive 1-D arrays are ort...... measurements with a PZT λ/2-pitch 3 MHz 62+62 RCA 2-D transducer probe. A synthetic aperture imaging sequence with single element transmissions at a time, is designed for imaging down to 14 cm at a volume rate of 44 Hz....

  14. Sensor Systems with Magnetic and Optomagnetic Readout of Rolling Circle Amplification Products

    DEFF Research Database (Denmark)

    Hansen, Mikkel Fougt; Donolato, Marco; Fock, Jeppe

    2016-01-01

    We are developing robust biosensors for homogeneous detection of rolling cirle amplification (RCA) products with magnetic and/or optomagnetic readouts based on surface-functionalized magnetic nanoparticles. Binding of RCA amplicons to nanoparticles modifies their ability to rotate in response...... to an applied oscillating magnetic field. As a result, magnetic or optical measurements of these changes in the rotational response of nanoparticles vs. frequency of the magnetic field can be used to quantitate the number of amplicons, and, hence, the concentration of target nucleic acid analytes. After...

  15. Methods of Hydrographic Surveying Used by Different Countries.

    Science.gov (United States)

    1983-03-01

    Numbers are averages for antenna variations in horizontal plane of 0-800. ARGO AFETR /RCA 19Bm RSS position error for 170 rumple APL/JHU points using...lower Chesapeake Bay network. Raydist-T AFETR /RCA 27m RSS fix accuracy, compared to Autotope, APL/JHU for 115 samples. Strong susceptibility to... effect is overcome by simply increasing the length between successive fixes -- instead of fixing every 3 meters, fix every 3.1 meters then every 3.2

  16. Dual-artery stenting of a type III single coronary artery from right aortic sinus

    Directory of Open Access Journals (Sweden)

    Shivanad Patil

    2015-12-01

    Full Text Available A single coronary artery presenting with stenosis in two of the three vessels arising from a common ostium is a rare anomaly Lipton et al. proposed a classification, which was modified by Yamanaka and Hobbs. In our case, a single coronary artery was giving rise to the LAD, left circumflex (LCx, and the right coronary artery (RCA. There was 80% stenosis in the ostium of the LCx. The RCA in the mid and distal segment had stenosis of 80% and 70%, respectively. We were able to successfully stent the three stenotic segments.

  17. Learning Team Breach of a Posted Barricade to Connect an Instrument to Power

    Energy Technology Data Exchange (ETDEWEB)

    Wilburn, Dianne Williams [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2017-04-19

    On February 15, 2017, a DESHF-STO HPFC (health physics field coordinator) was asked by an NEN-1 employee if they could move an instrument, a radiation dosimetry system, from A166A to another lab at TA-35 Building 2. The HPFC walked the job down and discovered the instrument was connected to power. The instrument had not been connected to power previously. See photo 1. The instrument is located within an RCA (radiological control area). Entry to connect the instrument to power the instrument requires contacting RP. RP personnel had not been contacted as required as stated in the RCA posting.

  18. Impact Resistance of Recycled Aggregate Concrete with Single and Hybrid Fibers

    Directory of Open Access Journals (Sweden)

    Ismail Sallehan

    2016-01-01

    Full Text Available This paper presents a recycled aggregate concrete (RAC mix that has been modified by adding treated recycled concrete aggregate (RCA and various types of fiber-reinforced systems. The effectiveness of these modifications in terms of energy absorption and impact resistance was evaluated and compared with that of the corresponding regular concrete, as well as with unmodified RAC specimens. Results clearly indicate that although modification of the RAC mix with treated RCA significantly enhances the impact resistance of RAC, further diversification with additional fiber, particularly those in hybrid form, can optimize the results.

  19. Brazilian sandy beaches: characteristics, ecosystem services, impacts, knowledge and priorities

    Directory of Open Access Journals (Sweden)

    Antonia Cecília Zacagnini Amaral

    Full Text Available ABSTRACT Sandy beaches constitute a key ecosystem and provide socioeconomic goods and services, thereby playing an important role in the maintenance of human populations and in biodiversity conservation. Despite the ecological and social importance of these ecosytems, Brazilian sandy beaches are significantly impacted by human interference, chemical and organic pollution and tourism, as well as global climate change. These factors drive the need to better understand the environmental change and its consequences for biota. To promote the implementation of integrated studies to detect the effects of regional and global environmental change on beaches and on other benthic habitats of the Brazilian coast, Brazilian marine researchers have established The Coastal Benthic Habitats Monitoring Network (ReBentos. In order to provide input for sample planning by ReBentos, we have conducted an intensive review of the studies conducted on Brazilian beaches and summarized the current knowledge about this environment. In this paper, we present the results of this review and describe the physical, biological and socioeconomics features of Brazilian beaches. We have used these results, our personal experience and worldwide literature to identify research projects that should be prioritized in the assessment of regional and global change on Brazilian sandy beaches. We trust that this paper will provide insights for future studies and represent a significant step towards the conservation of Brazilian beaches and their biodiversity.

  20. O ofício do procurador geral das missões e a formação de redes sociais da Companhia de Jesus nas missões do Grão-Pará e Maranhão = The office of the attorney general of missions and the formation of networks of the Society of Jesus in missions of the Grão-Pará and Maranhão

    Directory of Open Access Journals (Sweden)

    Joaquim, Mariana Alliatti

    2014-01-01

    Full Text Available O presente artigo tem como foco de investigação a função exercida por um ex-missionário da Companhia de Jesus no Brasil, integrante do grupo de jesuítas expulsos da Vice-Província do Grão Pará e Maranhão encarcerado na prisão de São Julião da Barra, a partir da expulsão em 1759. O Padre Bento da Fonseca, neste momento, atuava em Lisboa como procurador geral das missões da Vice-Província do Grão-Pará e Maranhão, junto a autoridades civis e eclesiásticas. Desta forma, objetiva-se enquadrar o cargo do procurador geral das missões da Companhia de Jesus na formação e consolidação de redes socioeconômicas e de poder entre os jesuítas e os vários setores da sociedade lusitana. A partir do conceito de redes sociais, conforme definiram Barnes (1987, Castells (2011 e Elias (1994, far-se-á uma seleção e análise evolutiva da correspondência e de outros escritos de Bento da Fonseca, complementada com a análise sincrônica de outros textos produzidos

  1. Ocorrência do ácaro vermelho europeu Panonychus ulmi (Koch (Tetranychidae associado à cultura da videira no Rio Grande do Sul, Brasil European red spider mite Panonychus ulmi (Koch (Tetranychidae occurrence of vineyards in Rio Grande do Sul, Brazil

    Directory of Open Access Journals (Sweden)

    Noeli Juarez Ferla

    2008-09-01

    Full Text Available Neste artigo é descrita ocorrência e o dano causado pelo ácaro vermelho europeu Panonychus ulmi (Koch associado à cultura da videira. As coletas foram realizadas na safra 2005-2006 em Vitis vinifera L. da cultivar Merlot, nos municípios de Bento Gonçalves e Candiota, no Estado do Rio Grande do Sul, Brasil. As folhas infestadas apresentaram bronzeamento, com manchas avermelhadas na face adaxial, resultando na queda prematura das mesmas. Esse é o primeiro registro do ácaro vermelho europeu danificando a cultura da videira no Rio Grande do Sul.The occurrence and the damage caused for the European red spider mite Panonychus ulmi (Koch associated to the culture of the grapevine are described. The collections had been carried through in 2005-2006 seasons in Vitis vinifera L. of cultivating Merlot in Bento Gonçalves and Candiota counties, in the state of Rio Grande do Sul, Brazil. The infested leaves had presented bronzing, with spots redly in the adaxial face resulting in the premature fall. This is the first register of the European red mite damaging the culture of the grapevine in Rio Grande do Sul.

  2. Biota acuática en la Amazonía Peruana: diversidad y usos como indicadores ambientales en el Bajo Urubamba (Cusco - Ucayali

    Directory of Open Access Journals (Sweden)

    Hernán Ortega

    2011-05-01

    Full Text Available En el presente trabajo se aplican índices biológicos de calidad ambiental y conservación, basados en el monitoreo biológico realizado entre año 2003 y 2009, en cinco localidades del río Bajo Urubamba. Fueron estudiadas las comunidades del plancton, bentos y peces. La diversidad del plancton comprendió 170 especies, basadas principalmente en Chlorophyta y Bacillariophyta. El bentos incluyó 112 especies, principalmente larvas y adultos de Arthropoda (Insecta. La diversidad de peces, incluye 176 especies, representadas por 26 familias y seis órdenes. El Índice Ephemeroptera + Plecoptera + Trichoptera (%EPT, califico el área de estudio entre normal a muy buena calidad. El índice de Integridad Biológica (IBI que determina el estado de conservación de los ambientes acuáticos, dio los mayores valores en Miaría y Sepahua. La elevada diversidad de las comunidades estudiados estaría relacionada a la heterogeneidad de hábitats y mayores recursos observados en la parte baja del área de estudio.

  3. Mercúrio total em cabelos: uma contribuição para se avaliar o nível de exposição em Poconé, Mato Grosso, Brasil

    Directory of Open Access Journals (Sweden)

    Flávia Nogueira

    Full Text Available Ocorrem na Bacia do Rio Bento Gomes (MT, às margens do Pantanal Mato-grossense, cerca de sessenta garimpos de ouro, onde o mercúrio é utilizado de forma intensiva nos processos de produção, através da formação de amálgamas que facilitam a aglutinação de partículas finas. A queima do amálgama nem sempre é feita em sistemas fechados de recuperação, havendo, portanto, perda de vapor para a atmosfera. Este estudo traz resultados de análises de mercúrio total nos cabelos de quatro grupos de voluntários que vivem em Poconé (MT, e faz uma caracterização geral do ambiente no que se refere à presença do metal na água e no sedimento do Rio Bento Gomes. Um equipamento de detecção por fluorescência foi usado para a determinação das concentrações, e os resultados indicam que os valores são mais baixos do que os de outras populações de áreas de garimpo no Brasil. Indicam também que a via ocupacional parece ser a mais eficiente rota potencial de contaminação da população por mercúrio.

  4. Uma análise das características da estrutura de governança em sistemas locais de produção e suas relações com a cadeia global An analysis of the characteristics of the governance struture in local production systems and its relations with the global chain

    Directory of Open Access Journals (Sweden)

    Renato Garcia

    2004-12-01

    Full Text Available Este trabalho tem o objetivo de analisar, de forma integrada, a problemática da governança global e local em sistemas locais de produção, com o intuito de verificar os condicionantes para a competitividade dos produtores e o desenvolvimento local. Para isso, são investigadas e comparadas duas experiências de sistemas locais de produção no Brasil: a indústria de calçados de Franca (SP e a de móveis em Bento Gonçalves (RS. As principais evidências apontam que o desenvolvimento de capacitações entre os produtores localizados é condicionado pelas formas de governança, global e local, sobre a cadeia produtiva.This paper analyzes industrial clusters, characterizing and integrating the view of global and local governance and identifying the conditioning factors of producer competitiveness and local development. To this end, the paper investigates two Brazilian industrial clusters: the footwear industry in Franca, SP and the furniture industry in Bento Gonçalves, RS. The main findings show that the forms of global governance of the production chain are crucial conditioning factors of the development of capabilities among local producers.

  5. Diversidad y el estado de conservación de cuerpos de agua Amazónicos en el nororiente del Perú

    Directory of Open Access Journals (Sweden)

    Hernán Ortega

    2013-05-01

    Full Text Available En el presente trabajo se describen la diversidad y estado de conservación, determinados por un inventario biológico rápido, entre el 24 y 30 de octubre de 2005, en cuerpos de agua del nororiente del Perú, ubicados, entre los 133 y 680 m de altitud, entre Tarapoto (San Martín y Yurimaguas (Loreto. Se colectaron datos y muestras en 26 estaciones. Los peces fueron colectados con redes de arrastre a la orilla, el bentos con red "Surber", y el plancton con red estándar (40 micras. En cada estación, se anotaron coordenadas (UTM y se describieron hábitats limnologicamente (pH, temperatura, conductividad, oxigeno disuelto. La riqueza de especies en peces fue de 95, predominan Characiformes y Siluriformes. La riqueza de especies de peces en fitoplancton fue de 74, en zooplancton, 22 especies y en bentos de 20 especies. Para determinar el estado de conservación se uso el Índice de Integridad Biológica (IBI para peces y EPT (Ephemeroptera, Plecoptera, y Trichoptera para la integridad de los ambientes acuáticos. Los resultados indican que en las zonas mejor conservadas se encuentran en los alrededores de Yurimaguas.

  6. How often do surgeons intervene on shoulder labral lesions detected at MR examination? A retrospective review of MR examinations correlated with arthroscopy

    Science.gov (United States)

    2014-01-01

    Objective: We report the prevalence of surgical intervention on shoulder labral lesions detected at MR examinations and how surgeons describe labral tears seen at MR examinations in their arthroscopy reports. Methods: A retrospective review of 100 consecutive patients aged 50 years or younger who had shoulder labral tears on MR and went on to have surgery performed. It was determined whether surgical intervention was performed on the MR lesions. Results: Of these 100 patients, 72 had superior labral anterior to posterior (SLAP) tears, 38 had posterior labral tears and 28 had anterior labral tears on MR examination. All 100 patients went on to arthroscopy. All lesions described on MRI were described on arthroscopy. Of the 72 SLAP tears, 64 were described as fraying on arthroscopy with 51 debrided. The remaining eight SLAP tears were tacked surgically. Of the 38 posterior labral tears, 36 were described as fraying on arthroscopy with 29 debrided and 2 had surgical tacking performed. Of the 28 anterior labral tears described on MR examination, 26 had surgical tacking performed and 2 were debrided. There were four SLAP tears, two anterior labral tears and three posterior labral tears seen on arthroscopy but not seen on MR examination. Conclusion: In this series, a high percentage of SLAP tears and posterior labral tears described on MR examination did not have surgical tacking. Most anterior labral tears had surgical tacking. Based on the above, our surgeons request we describe superior and posterior labral lesions as fraying and/or tearing, unless we can see a displaced tear. Most anterior labral lesions are treated with surgical tacking. Advances in knowledge: MRI allows for sensitive detection of labral tears. The tears often are not clinically significant. PMID:24712320

  7. Congenital rickets presenting as refractory respiratory distress at birth.

    Science.gov (United States)

    Tiwari, Soumya; Kumar, Rajesh; Singla, Shilpy; Dudeja, Ajay; Nangia, Sushma; Saili, Arvind

    2014-08-01

    Congenital rickets is a very rare entity in the spectrum of metabolic bone disease in children. The authors report an as yet unreported case of congenital rickets presenting with respiratory distress at birth. The radiographs of long bones and wrist showed generalized osteopenia with cupping and fraying of epiphyseal ends in the second week of life. The patient was managed with very high doses of vitamin D which led to clinico-radiological and biochemical improvement. More than being interesting for its extreme rarity, this report assumes importance as it brings forth the possibility of congenital rickets being a differential diagnosis for a newborn with respiratory distress.

  8. El Pleito de Ralco en 1919

    OpenAIRE

    ZAVALA CEPEDA, JOSÉ MANUEL

    2016-01-01

    El documento que presentamos a continuación, posee sin lugar a dudas un valor histórico significativo para el pueblo mapuche-pewenche y en especial para las comunidades de Alto Biobío. Con fecha 21 de mayo del año 1919 el misionero franciscano, fray Ángel Saavedra, escribía desde Chillán a su correligionario editor de El Misionero Franciscano (1892-1825), publicación periódica de la Orden Franciscana, para solicitarle insertara en dicha revista un alegato presentado a la Corte de Apelaciones ...

  9. Suministro de agua domiciliar a tres comunidades indígenas, Guatemala

    OpenAIRE

    Salvador Otazu, Roberto

    2014-01-01

    Este proyecto fin de carrera se propone dotar a comunidades indígenas de Fray Bartolomé de las Casas, Departamento de Alta Verapaz (Guatemala), de un mínimo de condiciones higiénico sanitarias básicas, como es el disponer de agua corriente. Se ha tomado como modelo a seguir la ampliación de la red de abastecimiento existente en San Pablo Comunja, a las comunidades de Chimenja, Esperanza Seamay y Nuevo Secapur. Se ampliarán el número de manantiales de abastecimiento (localización, aforos...

  10. Contribution to the Diatom flora of Southern Africa. II. Diatoms from the Hog's Back Region of the Amatola Mountains, Eastern Cape Province, South Africa

    CSIR Research Space (South Africa)

    Malcolm, HG

    1984-01-01

    Full Text Available roots of trees i~ the stream: 9 forms. Finn 26. The same: from liverworts [Aneura (Riccardia) fast igiata L. and L.] on Rhoj stones in running water: 48 forms. an 27. The same: from surface of mud in pools upstream: 35 forms. 28. The same: from... figures of the girdle view (Kieselalg. 2: 170. F. 678), of the typical form are unlike those seen in my material where they are groggily obese, having an intercalary band three to four times as wide as the valve. Similar girdle ~iews are seen in Fray...

  11. Enzymatic maceration of bone

    DEFF Research Database (Denmark)

    Uhre, Marie-Louise; Eriksen, Anne Marie; Simonsen, Kim Pilkjær

    2015-01-01

    and afterwards macerated by one of the two methods. DNA extraction was performed to see the effect of the macerations on DNA preservation. Furthermore, the bone pieces were examined in a stereomicroscope to assess for any bone damage. The results demonstrated that both methods removed all flesh/soft tissue from...... the bones. The DNA analysis showed that DNA was preserved on all the pieces of bones which were examined. Finally, the investigation suggests that enzyme maceration could be gentler on the bones, as the edges appeared less frayed. The enzyme maceration was also a quicker method; it took three hours compared...

  12. SURVIE EMBRYONNAIRE DU SAUMON ATLANTIQUE (SALMO SALAR L. DANS UN COURS D’EAU DU SUD DE SON AIRE DE RÉPARTITION, LA NIVELLE

    Directory of Open Access Journals (Sweden)

    DUMAS J.

    2007-01-01

    Full Text Available L’évaluation de la survie du saumon Atlantique entre la ponte et l’émergence des alevins hors des graviers est réalisée dans le bassin de la Nivelle dans les domaines accessible (trois tronçons et non accessible (trois tronçons aux géniteurs. Pour ce faire, des capsules d’incubation de 12 cm3, contenant des œufs fraîchement fécondés, sont insérées dans des frayères artificielles et naturelles. Le débit et la température de l’eau de surface, l’oxygène dissous des eaux de surface et interstitielle et les caractéristiques granulométriques du substrat des frayères sont contrôlés pendant toute la durée de l’expérience. La survie, de 28,6 % en moyenne dans l’ensemble des sites, est plus élevée dans les tronçons de l’amont (52,7 % dans la Très Haute Nivelle et son affluent, le Lapitxuri que dans les autres sites, dont ceux actuellement colonisés par l’espèce (21,5 %. Il n’est pas observé de différence de survie entre les frayères artificielles et naturelles. Les mortalités interviennent essentiellement lors des épisodes de crues avant l’éclosion. Une corrélation positive forte existe entre la saturation en oxygène de l’eau interstitielle et la survie. Pour une saturation minimum en oxygène au-dessous de 62 %, la survie reste inférieure à 27 %. En revanche, la composition granulométrique du substrat ne semble pas agir directement sur la survie. Ce facteur n’étant pas corrélé avec l’oxygène dissous, ceci suggère que dans ce cours d’eau, le flux circulant dans les frayères ne provient pas uniquement de l’eau de surface, mais aussi de la nappe alluviale pauvre en oxygène dissous.

  13. Ressenyes

    OpenAIRE

    Fernández Terricabras, Ignasi

    2008-01-01

    Index de les obres ressenyades: Fray Tomás GOMEZ, En reino extraño. Relación de la visita del Real Monasterio de Valldigna. Autobiografía, vida cotidiana y lucha política en la España de Carlos II. Edición crítica y estudios de Fernando Andrés Robres, Rafael Benítez Sánchez-Blanco y Eugenio Císcar Pallarés

  14. Stent fabric fatigue of grafts supported by Z-stents versus ringed stents: an in vitro buckling test.

    Science.gov (United States)

    Lin, Jing; Wang, Lu; Guidoin, Robert; Nutley, Mark; Song, Ge; Zhang, Ze; Du, Jia; Douville, Yvan

    2014-03-01

    Stent-grafts externally fitted with a Z-shaped stents were compared to devices fitted with ringed stents in an in vitro oscillating fatigue machine at 200 cycles per minute and a pressure of 360 mmHg for scheduled durations of up to 1 week. The devices fitted with Z-stents showed a considerably lower endurance limit to buckling compared to the controls. The contact between the apexes of adjacent Z-stents resulted in significant damage to the textile scaffolds and polyester fibers due to the sharp angle of the Z-stents. The ringed stents did not cause any fraying in the textile scaffolds.

  15. ¿La imitación o el arte de copiar?

    Directory of Open Access Journals (Sweden)

    José Luis García

    2015-01-01

    Full Text Available A lo largo de los siglos y en diferentes manifestaciones artísticas (pintura, literatura, música, la imitación o el arte de copiar (plagio es una palabra muy dura ha sido frecuente en los maestros y en los aprendices unos por "ley de procreación" (Fray Luis de León, otros por aprendizaje y otros por suplir sus carencias y lograr la fama. El texto expone algunos de estos casos e ingeniosas opiniones al respecto

  16. Universalidad e intertextualidad en Gastón Baquero : (la raíz, el tronco y las ramas : España, Cuba e Hispanoamérica en el árbol de su poesía)

    OpenAIRE

    Aradas Blanco, Diana

    2014-01-01

    [ES]Esta tesis trata sobre la huella de la literatura española, cubana e hispanoamericana en la poesía de Gastón Baquero. La presencia de la literatura española se vertebra en torno a tres etapas: la literatura medieval, la renacentista y barroca (con autores como Garcilaso de la Vega, Fray Luis de León, San Juan de la Cruz, Santa Teresa de Jesús, Góngora, Calderón de la Barca, Quevedo, Lope de Vega, o Cervantes) y el periodo comprendido desde el Romanticismo (con alusiones a Bécquer o Espron...

  17. Utilization of recycled concrete aggregates in structural concrete by applying a fraction partitioning model

    NARCIS (Netherlands)

    Wouw, van de P.M.F.; Doudart de la Grée, G.C.H.; Florea, M.V.A.; Brouwers, H.J.H.; Bilek, V.; Kersner, Z.

    2014-01-01

    The recycling of concrete waste into new structural concrete reduces the utilization of raw materials, decreases transport and production energy cost, and saves the use of limited landfill space. Currently, recycling involves the use of recycled concrete aggregates (RCA) as road base material or in

  18. Toxicity and environmental and economic performance of fly ash and recycled concrete aggregates use in concrete: A review.

    Science.gov (United States)

    Kurda, Rawaz; Silvestre, José D; de Brito, Jorge

    2018-04-01

    This paper presents an overview of previous studies on the environmental impact (EI) and toxicity of producing recycled concrete aggregates (RCA), fly ash (FA), cement, superplasticizer, and water as raw materials, and also on the effect of replacing cement and natural aggregates (NA) with FA and RCA, respectively, on the mentioned aspects. EI and toxicity were analysed simultaneously because considering concrete with alternative materials as sustainable depends on whether their risk assessment is high. Therefore, this study mainly focuses on the cradle-to-gate EI of one cubic meter of concrete, namely abiotic depletion potential (ADP), global warming potential (GWP), ozone depletion potential (ODP), photochemical ozone creation (POCP), acidification potential (AP), eutrophication potential (EP), non-renewable energy (PE-NRe) and renewable energy (PE-Re). In terms of toxicity, leachability (chemical and ecotoxicological characterization) was considered. The results also include the economic performance of these materials, and show that the incorporation of FA in concrete significantly decreases the EI and cost of concrete. Thus, the simultaneous incorporation of FA and RCA decrease the EI, cost, use of landfill space and natural resources extraction. Nonetheless, the leaching metals of FA decrease when they are incorporated in concrete. Relative to FA, the incorporation of RCA does not significantly affect the EI and cost of concrete, but it significantly reduces the use of landfill space and the need of virgin materials.

  19. Biological monitoring of the micro watershed - Canada del Dragon

    International Nuclear Information System (INIS)

    Fernandez, H.; Rossetti, K.; Caceres, T.; Palma, R.; Garcia, P.; De la Rosa, A.; Seoane, I.

    2012-01-01

    The working group under the Uruguay RCA L-5053 project is about La canada del Dragon (located in Santa Lucia basin - Uruguay) evaluation using benthic macro invertebrates. The main problems of the study area were the riverbanks expansion, the erosion and the pesticides impact on the native fish. The group implemented the water quality evaluation through the study of the invertebrates in the basin.

  20. Design of cryptographically secure AES like S-Box using second-order reversible cellular automata for wireless body area network applications

    Science.gov (United States)

    Rafi Ahamed, Shaik

    2016-01-01

    In biomedical, data security is the most expensive resource for wireless body area network applications. Cryptographic algorithms are used in order to protect the information against unauthorised access. Advanced encryption standard (AES) cryptographic algorithm plays a vital role in telemedicine applications. The authors propose a novel approach for design of substitution bytes (S-Box) using second-order reversible one-dimensional cellular automata (RCA2) as a replacement to the classical look-up-table (LUT) based S-Box used in AES algorithm. The performance of proposed RCA2 based S-Box and conventional LUT based S-Box is evaluated in terms of security using the cryptographic properties such as the nonlinearity, correlation immunity bias, strict avalanche criteria and entropy. Moreover, it is also shown that RCA2 based S-Boxes are dynamic in nature, invertible and provide high level of security. Further, it is also found that the RCA2 based S-Box have comparatively better performance than that of conventional LUT based S-Box. PMID:27733924

  1. Report on the workshop to review waste inventory, waste characteristics and reference site candidates

    International Nuclear Information System (INIS)

    1997-07-01

    There is a need of co-operation among Regional Co-operative Agreement (RCA) Member States in the field of low and intermediate level waste (LILW) disposal. An integrated approach is essential for successful establishment of LILW disposal facilities in RCA Member States. This would include: a) identification of waste inventory and characteristics; b) guidelines for implementation of LILW disposal; c) regulatory guidelines; d) safety assessment; e) quality assurance; and f) public acceptance. This project will focus on technical issues. The overall objective of the project, established in the project formulation meeting, is to assist RCA Member States in establishing national disposal activities for radioactive waste from nuclear applications by providing expert advice and training on techniques and methodology associated with planning and establishment of disposal facilities and to obtain improved knowledge of key staff members for the implementation of LILW disposal. The purpose of this workshop was to identify waste inventories, waste characteristics, site characteristics (generic or site specific) for disposal of LILW in RCA Member States of the project and identify conceptual reference site conditions and consider reference repository concepts preliminarily. Also the workshop was to establish an action plan of the next step. The workshop was held in Shanghai, China from 7 to 9 July 1997 and attended by 7 countries, i.e. Australia, China, Indonesia, Japan, Republic of Korea, Sri Lanka and Thailand. Refs, figs, tabs

  2. The Text of the Third Agreement to Extend the Regional Co-operative Agreement for Research, Development and Training related to Nuclear Science and Technology of 1972

    International Nuclear Information System (INIS)

    1987-09-01

    The text of the Third Agreement to Extend the Regional Co-operative Agreement for Research, Development and Training Related to Nuclear Science and Technology of 1972 the RCA Agreement, extended first in 1977 and then in 1982, for a further period of five years with effect from 12 June 1987, is reproduced herein for the information of all Members [fr

  3. The Tanda: A Practice at the Intersection of Mathematics, Culture, and Financial Goals

    Science.gov (United States)

    Martin, Lee; Goldman, Shelley; Jimenez, Osvaldo

    2009-01-01

    We present an analysis and discussion of the "tanda," a multiperson pooled credit and savings scheme (a rotating credit association or RCA), as described by two informants from Mexican immigrant communities in California. In the tanda, participants contribute regularly to a common fund which is distributed to participants on a rotating…

  4. Recycled concrete aggregate as road base: Leaching constituents and neutralization by soil Interactions and dilution.

    Science.gov (United States)

    Gupta, Nautasha; Kluge, Matt; Chadik, Paul A; Townsend, Timothy G

    2018-02-01

    Recycled Concrete Aggregate (RCA) is often used as a replacement for natural aggregate in road construction activities because of its excellent mechanical properties, and this trend should increase as more transportation departments include RCA in specifications and design manuals. Concerns raised by some engineers and contractors include impacts from leachate generated by RCA, both from transport of metals to water sources and the impact of a high pH leachate on corrosion of underlying metal drainage pipes. In this study, RCA collected from various regions of Florida exhibited pH ranging from 10.5 to 12.3. Concentrations of Al, Ba, Cr, Fe, Mo, Na, Ni, Sb, and Sr measured using batch leaching tests exceeded applicable risk-based thresholds on at least some occasions, but the concentrations measured suggest that risk to water supplies should be controlled because of dilution and attenuation. Two mechanisms of pH neutralization were evaluated. Soil acidity plays a role, but laboratory testing and chemical modeling found that at higher liquid-to-solid ratios the acidity is exhausted. If high pH leachate did reach groundwater, chemical modeling indicated that groundwater dilution and carbonation would mitigate groundwater pH effects. Copyright © 2017 Elsevier Ltd. All rights reserved.

  5. Surgical exclusion of postsurgical pseudoaneurysm of the ascending aorta

    Science.gov (United States)

    Barik, Ramachandra; Patnaik, Amar Narayana; Kumar, Ravintula Venkata; Mohapatra, Rudra Prasad; Medep, Vikas; Nemani, Lalita

    2014-01-01

    Pseudoaneurysm of ascending aorta after cardiac surgery is rare in children. We report a case of successful surgical exclusion of ascending aortic pseudoaneurysm in a 15-year-old boy. The neck of the aneurysm was in close proximity to the right coronary artery (RCA). PMID:24987261

  6. Surgical exclusion of postsurgical pseudoaneurysm of the ascending aorta

    Energy Technology Data Exchange (ETDEWEB)

    Barik, Ramachandra; Patnaik, Amar Narayana [Department of Cardiology, Nizam' s Institute of Medical Sciences, Hyderabad, Andhra Pradesh (India); Kumar, Ravintula Venkata; Mohapatra, Rudra Prasad [Department of Cardiothoracic Surgery, Nizam' s Institute of Medical Sciences, Hyderabad, Andhra Pradesh (India); Medep, Vikas; Nemani, Lalita [Department of Cardiology, Nizam' s Institute of Medical Sciences, Hyderabad, Andhra Pradesh (India)

    2014-01-01

    Pseudoaneurysm of ascending aorta after cardiac surgery is rare in children. We report a case of successful surgical exclusion of ascending aortic pseudoaneurysm in a 15-year-old boy. The neck of the aneurysm was in close proximity to the right coronary artery (RCA)

  7. Surgical exclusion of postsurgical pseudoaneurysm of the ascending aorta

    Directory of Open Access Journals (Sweden)

    Ramachandra Barik

    2014-01-01

    Full Text Available Pseudoaneurysm of ascending aorta after cardiac surgery is rare in children. We report a case of successful surgical exclusion of ascending aortic pseudoaneurysm in a 15-year-old boy. The neck of the aneurysm was in close proximity to the right coronary artery (RCA.

  8. 45 CFR 400.83 - Mediation and fair hearings.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 2 2010-10-01 2010-10-01 false Mediation and fair hearings. 400.83 Section 400.83... Employment § 400.83 Mediation and fair hearings. (a) Mediation—(1) Public/private RCA program. The State must ensure that a mediation period prior to imposition of sanctions is provided to refugees by local...

  9. Toxicity and environmental and economic performance of fly ash and recycled concrete aggregates use in concrete: A review

    Directory of Open Access Journals (Sweden)

    Rawaz Kurda

    2018-04-01

    Full Text Available This paper presents an overview of previous studies on the environmental impact (EI and toxicity of producing recycled concrete aggregates (RCA, fly ash (FA, cement, superplasticizer, and water as raw materials, and also on the effect of replacing cement and natural aggregates (NA with FA and RCA, respectively, on the mentioned aspects. EI and toxicity were analysed simultaneously because considering concrete with alternative materials as sustainable depends on whether their risk assessment is high. Therefore, this study mainly focuses on the cradle-to-gate EI of one cubic meter of concrete, namely abiotic depletion potential (ADP, global warming potential (GWP, ozone depletion potential (ODP, photochemical ozone creation (POCP, acidification potential (AP, eutrophication potential (EP, non-renewable energy (PE-NRe and renewable energy (PE-Re. In terms of toxicity, leachability (chemical and ecotoxicological characterization was considered. The results also include the economic performance of these materials, and show that the incorporation of FA in concrete significantly decreases the EI and cost of concrete. Thus, the simultaneous incorporation of FA and RCA decrease the EI, cost, use of landfill space and natural resources extraction. Nonetheless, the leaching metals of FA decrease when they are incorporated in concrete. Relative to FA, the incorporation of RCA does not significantly affect the EI and cost of concrete, but it significantly reduces the use of landfill space and the need of virgin materials. Keywords: Materials science, Environmental science, Industry, Economics, Safety engineering

  10. On the measurement of comparative advantage

    NARCIS (Netherlands)

    Hoen, A.R.; Oosterhaven, J.

    This paper shows-that the standard measure of revealed comparative advantage (RCA), ranging from 0 to infinity, has problematic properties. Due to its multiplicative specification, it has a moving mean larger than its expected value of 1, while its distribution strongly depends on the number of

  11. On the measurement of comparative advantage

    NARCIS (Netherlands)

    Hoen, Alex R.

    2001-01-01

    This article shows that the distribution of the standard measure of revealed comparative advantage (RCA), which runs from 0 to 8, has problematic properties. Due to its multiplicative specification, it has a moving mean without a useful interpretation, while its distribution depends on the number of

  12. CASE REPORT Dual (type IV) left anterior descending artery

    African Journals Online (AJOL)

    about 1.38%. [1,3] This anomaly is seen relatively often with congenital malformations such as complete transposition of the great arteries and tetralogy of Fallot.[2]. When a short or hypoplastic LAD is detected, a differential diagnosis should be sought. There may be a long dominant posterior descending branch of the RCA, ...

  13. Molecular Beacon Enables Combination of Highly Processive and Highly Sensitive Rolling Circle Amplification Readouts for Detection of DNA-Modifying Enzymes

    DEFF Research Database (Denmark)

    Kristoffersen, Emil Laust; Gonzales, Maria; Stougaard, Magnus

    2015-01-01

    is separated, giving rise to a fluorescent signal, measurable in pseudo real-time using a qPCR machine or in a fluorimeter. The RCA products in complex with the molecular beacon can subsequently be moved to microscopic slides and analyzed in a fluorescence microscope. We describe the proof of the principle...

  14. Psychometric Analysis of Role Conflict and Ambiguity Scales in Academia

    Science.gov (United States)

    Khan, Anwar; Yusoff, Rosman Bin Md.; Khan, Muhammad Muddassar; Yasir, Muhammad; Khan, Faisal

    2014-01-01

    A comprehensive Psychometric Analysis of Rizzo et al.'s (1970) Role Conflict & Ambiguity (RCA) scales were performed after its distribution among 600 academic staff working in six universities of Pakistan. The reliability analysis includes calculation of Cronbach Alpha Coefficients and Inter-Items statistics, whereas validity was determined by…

  15. Determination of toxic elements in Malaysian foodstuffs

    International Nuclear Information System (INIS)

    Hamzah, Z.; Wood, A.K.H.; Mahmood, C.S.; Hamzah, S.

    1988-01-01

    This project is concentrating on the analysis of toxic elements content in seafoods including fishes, mussel, squid and prawn. Samples were collected from various places throughout Malay Peninsular. Samples were prepared according to RCA research protocol - nuclear techniques for toxic element in foodstuffs. Techniques used for elemental analysis were neutron activation analysis (instrumental and radiochemical) and anodic stripping voltametry. (author). 9 refs, 9 tabs

  16. Contes et identité : Wanto dans les contes gbaya et dans la ...

    African Journals Online (AJOL)

    ... Gbaya identity by Gbaya artists. The fundamental role of Wanto in building Gbaya identity shows that oral literature is still vibrant and finds its place in new communication media. Keywords: Central African Republic (CAR/RCA), Gbaya identity; Gbaya oral tradition; oral tradition and new media, Wanto, the spider character.

  17. The cause and influence of self-cementing properties of fine recycled concrete aggregates on the properties of unbound sub-base

    International Nuclear Information System (INIS)

    Poon, C.-S.; Qiao, X.C.; Chan, Dixon

    2006-01-01

    The use of coarse recycled concrete aggregates (CRCA) in conjunction with fine recycled concrete aggregates (FRCA) as sub-base materials has been widely studied. Although research results indicate that it is feasible to employ both CRCA and FRCA as granular sub-base, the influence of the unhydrated cement in the adhered mortar of the RCA on the properties of the sub-base materials has not been thoroughly studied. Generally, it is known that the strength of the sub-base materials prepared with RCA increases over time. However, this mechanism, known as the self-cementing properties, is not well understood and is believed to be governed by the properties of the fine portion of the RCA (<5 mm). This paper presents an investigation on the cause of the self-cementing properties by measuring X-ray diffraction patterns, pH values, compressive strength and permeability of various size fractions of the FRCA obtained from a commercially operated construction and demolition waste recycling plant. Their influence on the overall sub-base materials was determined. The results indicate that the size fractions of <0.15 and 0.3-0.6 mm (active fractions) were most likely to be the principal cause of the self-cementing properties of the FRCA. However, the effects on the properties of the overall RCA sub-base materials were minimal if the total quantity of the active fractions was limited to a threshold by weight of the total fine aggregate

  18. A History of Satellite Reconnaissance. Volume 2A. SAMOS (REDACTED)

    Science.gov (United States)

    1973-10-01

    CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT NUMBER 5e. TASK NUMBER 5f. WORK UNIT NUMBER 7. PERFORMING... Disneyland aspe, ts of some RCA actiVities, results of system testa conducted late in March seemed to have Cully justilied the Reconnaissance Laboratory

  19. ST-segment depression in aVR as a predictor of culprit artery in acute inferior wall ST-segment elevation myocardial infarction

    Directory of Open Access Journals (Sweden)

    Ahmed Hafez el-neklawy

    2014-03-01

    Conclusions: ST depression in aVR is common in patients with LCX-related acute inferior myocardial infarction. The ST changes in this lead are associated with an excellent specificity and a good sensitivity in differentiating LCX from RCA as the IRA.

  20. Requirements of cyclin a for mitosis are independent of its subcellular localization.

    Science.gov (United States)

    Dienemann, Axel; Sprenger, Frank

    2004-06-22

    Cyclin A (CycA), the only essential mitotic cyclin in Drosophila, is cytoplasmic during interphase and accumulates in the nucleus during prophase. We show that interphase localization is mediated by Leptomycin B (LMB)-sensitive nuclear export. This is a feature shared with human CyclinB1, and it is assumed that nuclear accumulation is necessary for mitotic entry. Here, we tested if the unique mitotic function of CycA requires nuclear accumulation. We fused subcellular localization signals to CycA and tested their mitotic capability. Surprisingly, nuclear accumulation was not required, and even a membrane-tethered form of CycA was able to induce mitosis. We noted that Cyclin B (CycB) protein disappears prematurely in CycA mutants, reminiscent of rca1 mutants. Rca1 is an inhibitor of Fizzy-related-APC/C activity, and in rca1 mutants, mitotic cyclins are degraded in G2 of the 16(th) embryonic cell cycle. Overexpression of Rca1 can restore mitosis in CycA mutants, indicating that the mitotic failure of CycA mutants is caused by premature activation of the APC/C. The essential mitotic function of CycA is therefore not the activation of numerous mitotic substrates by Cdk1-dependent phosphorylation. Rather, CycA-dependent kinase activity is required to inhibit one inhibitor of mitosis, the Fzr protein.

  1. Impact of climate change on surface ozone and deposition of sulphur and nitrogen in Europe

    Energy Technology Data Exchange (ETDEWEB)

    Langner, J.; Bergstroem, R.; Foltescu, V. [Swedish Meteorological and Hydrological Institute, Norrkoeping (Sweden)

    2005-02-01

    The potential impact of regional climate change on the distribution and deposition of air pollutants in Europe has been studied using a regional chemistry/transport/deposition model, MATCH. MATCH was set up using meteorological output from two 10-year climate change experiments made with the Rossby Centre regional Atmospheric climate model version 1 (RCA1). RCA1 was forced by boundary conditions from two different global climate models using the IPCC IS92a (business as usual) emission scenario. The global mean warming in both the GCMs was 2.6 K and was reached in the period 2050-2070. Simulations with MATCH indicate substantial potential impact of regional climate change on both deposition of oxidised nitrogen and concentrations of surface ozone. The simulations show a strong increase in surface ozone expressed as AOT40 and mean of daily maximum over southern and central Europe and a decrease in northern Europe. The simulated changes in April-September AOT40 are significant in relation to inter-annual variability over extended areas. Changes in deposition of oxidised nitrogen are much smaller and also less coherent due to the strong inter-annual variability in precipitation in the RCA1 simulations and differences in the regional climate change simulated with RCA1 in the two regional scenarios. Changes in simulated annual deposition are significant in relation to inter-annual variability only over small areas. This indicates that longer simulation periods are necessary to establish changes in deposition. (author)

  2. Impact of climate change on surface ozone and deposition of sulphur and nitrogen in Europe

    Science.gov (United States)

    Langner, Joakim; Bergström, Robert; Foltescu, Valentin

    The potential impact of regional climate change on the distribution and deposition of air pollutants in Europe has been studied using a regional chemistry/transport/deposition model, MATCH. MATCH was set up using meteorological output from two 10-year climate change experiments made with the Rossby Centre regional Atmospheric climate model version 1 (RCA1). RCA1 was forced by boundary conditions from two different global climate models using the IPCC IS92a (business as usual) emission scenario. The global mean warming in both the GCMs was 2.6 K and was reached in the period 2050-2070. Simulations with MATCH indicate substantial potential impact of regional climate change on both deposition of oxidised nitrogen and concentrations of surface ozone. The simulations show a strong increase in surface ozone expressed as AOT40 and mean of daily maximum over southern and central Europe and a decrease in northern Europe. The simulated changes in April-September AOT40 are significant in relation to inter-annual variability over extended areas. Changes in deposition of oxidised nitrogen are much smaller and also less coherent due to the strong inter-annual variability in precipitation in the RCA1 simulations and differences in the regional climate change simulated with RCA1 in the two regional scenarios. Changes in simulated annual deposition are significant in relation to inter-annual variability only over small areas. This indicates that longer simulation periods are necessary to establish changes in deposition.

  3. Fibromuscular Dysplasia Leading to Spontaneous Coronary Artery Dissection with Sudden Cardiac Arrest

    Directory of Open Access Journals (Sweden)

    Ata Bajwa

    2015-01-01

    Full Text Available A 30-year-old previously healthy female, who was six-week postpartum, experienced sudden collapse and tonic-clonic seizure. Emergency medicine services arrived at the scene and the patient was found to be in ventricular fibrillation. Advanced cardiovascular life support (ACLS was initiated with return of spontaneous circulation. Afterwards, her initial EKG showed atrial fibrillation with rapid ventricular rate, ST elevation in leads II, III, and aVF, and ST depression in V2–V4. She was transferred to a tertiary care hospital where emergent angiogram was performed revealing obstruction of blood flow in the proximal and mid right coronary artery (RCA. A hazy and irregularly contoured appearance of the RCA was consistent with diagnosis of fibromuscular dysplasia. Subsequently, intravascular ultrasonogram (IVUS was performed which confirmed the diagnosis of RCA dissection. Successful revascularization of the RCA was performed using two bare mental stents. After a complicated course in hospital, she was discharged in stable condition and did very well overall.

  4. Photometric Observation and Light Curve Analysis of Binary System ...

    Indian Academy of Sciences (India)

    2016-01-27

    Jan 27, 2016 ... Photometric Observation and Light Curve Analysis of Binary System ER-Orionis ... February to April 2008 with the 51 cm telescope of Biruni Observatory of Shiraz University in U, B and V filters (Johnson system) and an RCA 4509 photomultiplier. ... Articles are also visible in Web of Science immediately.

  5. Recycled construction and demolition concrete waste as aggregate for structural concrete

    Directory of Open Access Journals (Sweden)

    Ashraf M. Wagih

    2013-12-01

    Full Text Available In major Egyptian cities there is a surge in construction and demolition waste (CDW quantities causing an adverse effect on the environment. The use of such waste as recycled aggregate in concrete can be useful for both environmental and economical aspects in the construction industry. This study discusses the possibility to replace natural coarse aggregate (NA with recycled concrete aggregate (RCA in structural concrete. An investigation into the properties of RCA is made using crushing and grading of concrete rubble collected from different demolition sites and landfill locations around Cairo. Aggregates used in the study were: natural sand, dolomite and crushed concretes obtained from different sources. A total of 50 concrete mixes forming eight groups were cast. Groups were designed to study the effect of recycled coarse aggregates quality/content, cement dosage, use of superplasticizer and silica fume. Tests were carried out for: compressive strength, splitting strength and elastic modulus. The results showed that the concrete rubble could be transformed into useful recycled aggregate and used in concrete production with properties suitable for most structural concrete applications in Egypt. A significant reduction in the properties of recycled aggregate concrete (RAC made of 100% RCA was seen when compared to natural aggregate concrete (NAC, while the properties of RAC made of a blend of 75% NA and 25% RCA showed no significant change in concrete properties.

  6. Aspects Concerning the Use of Recycled Concrete Aggregates

    Science.gov (United States)

    Robu, I.; Mazilu, C.; Deju, R.

    2016-11-01

    Natural aggregates (gravel and crushed) are essential non-renewable resources which are used for infrastructure works and civil engineering. Using recycled concrete aggregates (RCA) is a matter of high priority in the construction industry worldwide. This paper presents a study on the use of recycled aggregates, from a concrete of specified class, to acquire new cement concrete with different percentages of recycled aggregates.

  7. DNAzyme Feedback Amplification: Relaying Molecular Recognition to Exponential DNA Amplification.

    Science.gov (United States)

    Liu, Meng; Yin, Qingxin; McConnell, Erin M; Chang, Yangyang; Brennan, John D; Li, Yingfu

    2018-03-26

    Technologies capable of linking DNA amplification to molecular recognition are very desirable for ultrasensitive biosensing applications. We have developed a simple but powerful isothermal DNA amplification method, termed DNAzyme feedback amplification (DFA), that is capable of relaying molecular recognition to exponential DNA amplification. The method incorporates both an RNA-cleaving DNAzyme (RCD) and rolling circle amplification (RCA) carried out by a special DNA polymerase using a circular DNA template. DFA begins with a stimulus-dependent RCA reaction, producing tandemly linked RCDs in long-chain DNA products. These RCDs cleave an RNA-containing DNA sequence to form additional primers that hybridize to the circular DNA molecule, giving rise to DNA assemblies that act as the new inputs for RCA. The RCA reaction and the cleavage event keep on feeding each other autonomously, resulting in exponential growth of repetitive DNA sequences that can be easily detected. This method can be used for the detection of both nucleic acid based targets and non-nucleic acid analytes. In this article, we discuss the conceptual framework of the feedback amplification approach, the essential features of this method as well as remaining challenges and possible solutions. © 2018 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

  8. Plant mutation reports. Vol. 1, No. 3, December 2007

    International Nuclear Information System (INIS)

    2007-12-01

    This issue of the Plant Mutation Reports emphasises the recently concluded IAEA-RCA project on Mutant Multi-location Trial and Mutational Enhancement of genetic Diversity (RAS/5/040) which has developed 33 mutant varieties and dozens of promising mutant breeding lines with high yield potantial and/or improved agronomic characters, resistance and end user quality traits

  9. A Quantitative Assessment of the Research Chefs Association Core Competencies for the Practicing Culinologist

    Science.gov (United States)

    Bissett, Rachel L.; Cheng, Michael S. H.; Brannan, Robert G.

    2010-01-01

    Professional organizations have linked core competency to professional success and competitive strategy. The Research Chefs Assn. (RCA) recently released 43 core competencies for practicing culinologists. Culinology[R] is a profession that links skills of culinary arts and food science and technology in the development of food products. An online…

  10. Unileg Thermoelectric Generator Design for Oxide Thermoelectrics and Generalization of the Unileg Design Using an Idealized Metal

    DEFF Research Database (Denmark)

    Wijesooriyage, Waruna Dissanayaka; Rosendahl, Lasse; Brown, David R.

    2015-01-01

    the optimal area ratio for conductor and semiconductor given by the RCA. The results are further confirmed by finite-element analysis using COMSOL Multiphysics software. Furthermore, the U-TEG design is generalized by using an idealized metal with zero Seebeck coefficient. Even though the idealized metal has...

  11. Evaluation of waste concrete road materials for use in oyster aquaculture - Phase 3.

    Science.gov (United States)

    2016-08-01

    This project was the final phase of a three-phase project. The primary objective was to determine the suitability of recycled concrete aggregate (RCA) from road projects as a bottom conditioning material for on-bottom oyster aquaculture in the Chesap...

  12. Behaviour of Recycled Coarse Aggregate Concrete: Age and Successive Recycling

    Science.gov (United States)

    Sahoo, Kirtikanta; Pathappilly, Robin Davis; Sarkar, Pradip

    2016-06-01

    Recycled Coarse Aggregate (RCA) concrete construction technique can be called as `green concrete', as it minimizes the environmental hazard of the concrete waste disposal. Indian standard recommends target mean compressive strength of the conventional concrete in terms of water cement ratio ( w/ c). The present work is an attempt to study the behaviour of RCA concrete from two samples of parent concrete having different age group with regard to the relationship of compressive strength with water cement ratios. Number of recycling may influence the mechanical properties of RCA concrete. The influence of age and successive recycling on the properties such as capillary water absorption, drying shrinkage strain, air content, flexural strength and tensile splitting strength of the RCA concrete are examined. The relationship between compressive strength at different w/ c ratios obtained experimentally is investigated for the two parameters such as age of parent concrete and successive recycling. The recycled concrete using older recycled aggregate shows poor quality. While the compressive strength reduces with successive recycling gradually, the capillary water absorption increases abruptly, which leads to the conclusion that further recycling may not be advisable.

  13. EMP Design Guidelines for Naval Ship Systems

    Science.gov (United States)

    1975-08-22

    le xc Ci .ube irret i Type FXC it LA 38 Beads 4 * 1 svj- I * 1 1 \\ Measured 3( )0 Beads V i i V 30 Bead 1 s...ATTN: R. W. Rostrom RCA Corporation Government & Commercial Systems Astro Electronics Division P. 0. Box 800 Princeton, New Jersey 08540 ATTN

  14. Adenoviral vector-mediated gene expression in the nervous system of immunocompetent Wistar and T cell-deficient nude rats : preferential survival of transduced astroglial cells in nude rats

    NARCIS (Netherlands)

    Hermens, W.T.J.M.C.; Verhaagen, J

    1997-01-01

    In the present paper, we examined the effect of the adenoviral vector dosage, the role of T cells, and the influence of the presence of replication-competent adenovirus (RCA) in adenoviral vector stocks, on the efficacy of adenoviral vector-directed transgene expression in the facial nucleus of

  15. Photometric Observation and Light Curve Analysis of Binary System ...

    Indian Academy of Sciences (India)

    Abstract. Photometric observations of the over-contact binary ER ORI were performed during November 2007 and February to April 2008 with the 51cm telescope of Biruni Observatory of Shiraz University in U, B and V filters (Johnson system) and an RCA 4509 photomultiplier. We used these data to obtain the light curves ...

  16. Promotion of mitochondrial membrane complex assembly by a proteolytically inactive yeast Lon

    NARCIS (Netherlands)

    Rep, M; van Dijl, J M; Suda, K; Schatz, G; Grivell, L A; Suzuki, C K

    1996-01-01

    Afg3p and Rca1p are adenosine triphosphate (ATP)-dependent metalloproteases in yeast mitochondria. Cells lacking both proteins exhibit defects in respiration-dependent growth, degradation of mitochondrially synthesized proteins, and assembly of inner-membrane complexes. Defects in growth and protein

  17. Study Concerning Characterization of Some Recycled Concrete Aggregates

    Directory of Open Access Journals (Sweden)

    Robu Ion

    2016-03-01

    Full Text Available Using recycled concrete aggregates (RCA is a matter of high priority in the construction industry worldwide. In countries like the Netherlands, Denmark, Germany, USA, Japan, France recycled concrete aggregates obtained from demolition are valorized up to 90%, mainly for road construction and less in the manufacture of new concrete.

  18. Low Power S-Box Architecture for AES Algorithm using Programmable Second Order Reversible Cellular Automata: An Application to WBAN.

    Science.gov (United States)

    Gangadari, Bhoopal Rao; Ahamed, Shaik Rafi

    2016-12-01

    In this paper, we presented a novel approach of low energy consumption architecture of S-Box used in Advanced Encryption Standard (AES) algorithm using programmable second order reversible cellular automata (RCA 2 ). The architecture entails a low power implementation with minimal delay overhead and the performance of proposed RCA 2 based S-Box in terms of security is evaluated using the cryptographic properties such as nonlinearity, correlation immunity bias, strict avalanche criteria, entropy and also found that the proposed architecture is secure enough for cryptographic applications. Moreover, the proposed AES algorithm architecture simulation studies show that energy consumption of 68.726 nJ, power dissipation of 3.856 mW for 0.18- μm at 13.69 MHz and energy consumption of 29.408 nJ, power dissipation of 1.65 mW for 0.13- μm at 13.69 MHz. The proposed AES algorithm with RCA 2 based S-Box shows a reduction power consumption by 50 % and energy consumption by 5 % compared to best classical S-Box and composite field arithmetic based AES algorithm. Apart from that, it is also shown that RCA 2 based S-Boxes are dynamic in nature, invertible, low power dissipation compared to that of LUT based S-Box and hence suitable for Wireless Body Area Network (WBAN) applications.

  19. Dual (type IV) left anterior descending artery | Baskan | SA Journal of ...

    African Journals Online (AJOL)

    ... LAD originating from the right coronary artery (RCA). Dual LAD is a benign coronary artery anomaly, but should be recognised especially before interventional procedures. With the increasing use of multidedector computed tomography (MDCT), it is essential for radiologists to be aware of this entity and the cross-sectional ...

  20. Computed microtomography visualization and quantification of mouse ischemic brain lesion by nonionic radio contrast agents.

    Science.gov (United States)

    Dobrivojević, Marina; Bohaček, Ivan; Erjavec, Igor; Gorup, Dunja; Gajović, Srećko

    2013-02-01

    To explore the possibility of brain imaging by microcomputed tomography (microCT) using x-ray contrasting methods to visualize mouse brain ischemic lesions after middle cerebral artery occlusion (MCAO). Isolated brains were immersed in ionic or nonionic radio contrast agent (RCA) for 5 days and subsequently scanned using microCT scanner. To verify whether ex-vivo microCT brain images can be used to characterize ischemic lesions, they were compared to Nissl stained serial histological sections of the same brains. To verify if brains immersed in RCA may be used afterwards for other methods, subsequent immunofluorescent labeling with anti-NeuN was performed. Nonionic RCA showed better gray to white matter contrast in the brain, and therefore was selected for further studies. MicroCT measurement of ischemic lesion size and cerebral edema significantly correlated with the values determined by Nissl staining (ischemic lesion size: P=0.0005; cerebral edema: P=0.0002). Brain immersion in nonionic RCA did not affect subsequent immunofluorescent analysis and NeuN immunoreactivity. MicroCT method was proven to be suitable for delineation of the ischemic lesion from the non-infarcted tissue, and quantification of lesion volume and cerebral edema.

  1. Trends in land and water available for outdoor recreation

    Science.gov (United States)

    Lloyd C. Irland; Thomas Rumpf

    1980-01-01

    A data base for assessing the availability of land for outdoor recreation does not exist. Information on related issues such as vandalism, easements, and land posting is scanty. Construction of a data base for assessing land availability should be a high priority for USFS and HCRS, and for SCORP's and the RPA and RCA assessments.

  2. Improvement of multicrystalline silicon wafer solar cells by post ...

    Indian Academy of Sciences (India)

    Administrator

    post-fabrication wet-chemical etching in phosphoric acid. A MEFOUED1,2,*, M FATHI1, ... and RCA decontamination stages by putting them in a bath made of ... found to be decreasing after chemical attack as shown in figure 2. In order to ...

  3. IAEA program of regional technical cooperation in Asia

    International Nuclear Information System (INIS)

    Airey, P.L.

    1986-01-01

    A list of project activities of the IAEA's Regional Cooperative Agreement for Research, Development and Training Related to Nuclear Science and Technology (RCA) for Asia and the Pacific regions is presented. They cover the fields of food and agriculture, industry, medicine and nuclear science. Activities under the United Nations Development Program (UNDP) Industrial Project are summarised

  4. Design of cryptographically secure AES like S-Box using second-order reversible cellular automata for wireless body area network applications.

    Science.gov (United States)

    Gangadari, Bhoopal Rao; Rafi Ahamed, Shaik

    2016-09-01

    In biomedical, data security is the most expensive resource for wireless body area network applications. Cryptographic algorithms are used in order to protect the information against unauthorised access. Advanced encryption standard (AES) cryptographic algorithm plays a vital role in telemedicine applications. The authors propose a novel approach for design of substitution bytes (S-Box) using second-order reversible one-dimensional cellular automata (RCA 2 ) as a replacement to the classical look-up-table (LUT) based S-Box used in AES algorithm. The performance of proposed RCA 2 based S-Box and conventional LUT based S-Box is evaluated in terms of security using the cryptographic properties such as the nonlinearity, correlation immunity bias, strict avalanche criteria and entropy. Moreover, it is also shown that RCA 2 based S-Boxes are dynamic in nature, invertible and provide high level of security. Further, it is also found that the RCA 2 based S-Box have comparatively better performance than that of conventional LUT based S-Box.

  5. haplotypes of hookworms (Ancylostoma)

    African Journals Online (AJOL)

    Melanie

    2012-01-26

    Jan 26, 2012 ... resulting tree, as well as their genetic distance from other samples .... E6. RTAYR1. 545. A. brasiliense. JQ083592. 18, 19. E7. RTAYR1. 545 ..... Traub RJ, Inpankaew T, Sutthikornchai C, Sukthana Y, Thompson RCA. (2008).

  6. The Text of the Second Agreement to Extend the Regional Co-operative Agreement for Research, Development and Training related to Nuclear Science and Technology of 1972

    International Nuclear Information System (INIS)

    1982-12-01

    The text of the Second Agreement to Extend the Regional Co-operative Agreement for Research, Development and Training Related to Nuclear Science and Technology of 1972 the RCA Agreement, fist extended in 1977, for a further period of five years with effect from 12 June 1982, is reproduced herein for the information of all Members

  7. Individualized radiation dose control in 256-slice CT coronary angiography (CTCA) in retrospective ECG-triggered helical scans: Using a measure of body size to adjust tube current selection

    Energy Technology Data Exchange (ETDEWEB)

    Li, Jing-Lei, E-mail: lijinglei80@126.com [Department of Radiology, Guangdong Academy of Medical Sciences, Guangdong General Hospital, 106 Zhongshan Er Road, Guangzhou 510080 (China); Huang, Mei-Ping, E-mail: huang_meiping@yahoo.com.cn [Department of Radiology, Guangdong Academy of Medical Sciences, Guangdong General Hospital, 106 Zhongshan Er Road, Guangzhou 510080 (China); Liang, Chang-Hong, E-mail: cjr.lchh@vip.163.com [Department of Radiology, Guangdong Academy of Medical Sciences, Guangdong General Hospital, 106 Zhongshan Er Road, Guangzhou 510080 (China); Zhao, Zhen-Jun, E-mail: junabc2006@hotmail.com [Department of Radiology, Guangdong Academy of Medical Sciences, Guangdong General Hospital, 106 Zhongshan Er Road, Guangzhou 510080 (China); Liu, Hui, E-mail: liuhuijiujiu@gmail.com [Department of Radiology, Guangdong Academy of Medical Sciences, Guangdong General Hospital, 106 Zhongshan Er Road, Guangzhou 510080 (China); Cui, Yan-Hai, E-mail: yanhai_cui@126.com [Department of Radiology, Guangdong Academy of Medical Sciences, Guangdong General Hospital, 106 Zhongshan Er Road, Guangzhou 510080 (China); Liu, Qi-Shun, E-mail: liuqishun@yeah.net [Department of Radiology, Guangdong Academy of Medical Sciences, Guangdong General Hospital, 106 Zhongshan Er Road, Guangzhou 510080 (China); Zhang, Jin-E., E-mail: zhjine@yahoo.com.cn [Department of Radiology, Guangdong Academy of Medical Sciences, Guangdong General Hospital, 106 Zhongshan Er Road, Guangzhou 510080 (China); Yang, Lin, E-mail: yanglin001517@163.com [Department of Radiology, Guangdong Academy of Medical Sciences, Guangdong General Hospital, 106 Zhongshan Er Road, Guangzhou 510080 (China); Ivanc, Thomas B., E-mail: Thomas.ivanc@philips.com [CT Clinical Science, Philips Healthcare, Highland Heights, OH (United States); Yanof, Jeffrey H., E-mail: Jeffrey.yanof@philips.com [CT Clinical Science, Philips Healthcare, Highland Heights, OH (United States)

    2012-11-15

    Purpose: To reduce radiation dose for retrospective ECG-triggered helical 256-slice CTCA by determining an optimal body size index to prospectively adjust tube current. Methods: 102 consecutive patients with suspected CAD underwent retrospective ECG-triggered CTCA using 256-slice CT scanner. Six body size indexes including BMI, nipple level (NL) bust, thoracic anteroposterior diameter at NL, chest circumference (CC) at NL, left main and right coronary artery (RCA) origin level were measured and their correlation with noise was evaluated using linear regression. An equation was developed to use this index to adjust tube current. Additional 102 consecutive patients were scanned with the index-based mA s adjustment. A t-test for independent samples was used to compare radiation dose levels with and without the index-based mA s selection method. Results: Linear regression indicated that CC RCA had the best correlation with noise (R{sup 2} = 0.603). Effective radiation dose was reduced from 16.6 {+-} 0.9 to 9.8 {+-} 2.7 mSv (p < 0.01), i.e. 40.9% lower dose with the CC RCA-adapted tube current method. The image quality scores indicated no significant difference with and without the size-based mA s selection method. Conclusion: An accessible measure of body size, such as CC RCA, can be used to adapt tube current for individualized radiation dose control.

  8. Individualized radiation dose control in 256-slice CT coronary angiography (CTCA) in retrospective ECG-triggered helical scans: Using a measure of body size to adjust tube current selection

    International Nuclear Information System (INIS)

    Li, Jing-Lei; Huang, Mei-Ping; Liang, Chang-Hong; Zhao, Zhen-Jun; Liu, Hui; Cui, Yan-Hai; Liu, Qi-Shun; Zhang, Jin-E.; Yang, Lin; Ivanc, Thomas B.; Yanof, Jeffrey H.

    2012-01-01

    Purpose: To reduce radiation dose for retrospective ECG-triggered helical 256-slice CTCA by determining an optimal body size index to prospectively adjust tube current. Methods: 102 consecutive patients with suspected CAD underwent retrospective ECG-triggered CTCA using 256-slice CT scanner. Six body size indexes including BMI, nipple level (NL) bust, thoracic anteroposterior diameter at NL, chest circumference (CC) at NL, left main and right coronary artery (RCA) origin level were measured and their correlation with noise was evaluated using linear regression. An equation was developed to use this index to adjust tube current. Additional 102 consecutive patients were scanned with the index-based mA s adjustment. A t-test for independent samples was used to compare radiation dose levels with and without the index-based mA s selection method. Results: Linear regression indicated that CC RCA had the best correlation with noise (R 2 = 0.603). Effective radiation dose was reduced from 16.6 ± 0.9 to 9.8 ± 2.7 mSv (p < 0.01), i.e. 40.9% lower dose with the CC RCA-adapted tube current method. The image quality scores indicated no significant difference with and without the size-based mA s selection method. Conclusion: An accessible measure of body size, such as CC RCA, can be used to adapt tube current for individualized radiation dose control.

  9. Rapid detection of ERG11 gene mutations in clinical Candida albicans isolates with reduced susceptibility to fluconazole by rolling circle amplification and DNA sequencing

    Directory of Open Access Journals (Sweden)

    Ellis David

    2009-08-01

    Full Text Available Abstract Background Amino acid substitutions in the target enzyme Erg11p of azole antifungals contribute to clinically-relevant azole resistance in Candida albicans. A simple molecular method for rapid detection of ERG11 gene mutations would be an advantage as a screening tool to identify potentially-resistant strains and to track their movement. To complement DNA sequencing, we developed a padlock probe and rolling circle amplification (RCA-based method to detect a series of mutations in the C. albicans ERG11 gene using "reference" azole-resistant isolates with known mutations. The method was then used to estimate the frequency of ERG11 mutations and their type in 25 Australian clinical C. albicans isolates with reduced susceptibility to fluconazole and in 23 fluconazole-susceptible isolates. RCA results were compared DNA sequencing. Results The RCA assay correctly identified all ERG11 mutations in eight "reference" C. albicans isolates. When applied to 48 test strains, the RCA method showed 100% agreement with DNA sequencing where an ERG11 mutation-specific probe was used. Of 20 different missense mutations detected by sequencing in 24 of 25 (96% isolates with reduced fluconazole susceptibility, 16 were detected by RCA. Five missense mutations were detected by both methods in 18 of 23 (78% fluconazole-susceptible strains. DNA sequencing revealed that mutations in non-susceptible isolates were all due to homozygous nucleotide changes. With the exception of the mutations leading to amino acid substitution E266D, those in fluconazole-susceptible strains were heterozygous. Amino acid substitutions common to both sets of isolates were D116E, E266D, K128T, V437I and V488I. Substitutions unique to isolates with reduced fluconazole susceptibility were G464 S (n = 4 isolates, G448E (n = 3, G307S (n = 3, K143R (n = 3 and Y123H, S405F and R467K (each n = 1. DNA sequencing revealed a novel substitution, G450V, in one isolate. Conclusion The sensitive RCA

  10. Less increase of CT-based calcium scores of the coronary arteries. Effect three years after breast-conserving radiotherapy using breath-hold

    Energy Technology Data Exchange (ETDEWEB)

    Mast, M.E.; Kempen-Harteveld, M.L. van; Petoukhova, A.L. [Centre West, Radiotherapy, The Hague (Netherlands); Heijenbrok, M.W. [Medical Center Haaglanden, Department of Radiology, The Hague (Netherlands); Scholten, A.N. [Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital, Department of Radiation Oncology, Amsterdam (Netherlands); Wolterbeek, R. [Leiden University Medical Centre, Department of Medical Statistics and Bioinformatics, Leiden (Netherlands); Schreur, J.H.M. [Medical Center Haaglanden, Department of Cardiology, The Hague (Netherlands); Struikmans, H. [Centre West, Radiotherapy, The Hague (Netherlands); Leiden University Medical Centre, Department of Clinical Oncology, Leiden (Netherlands)

    2016-10-15

    The aim of this prospective longitudinal study was to compare coronary artery calcium (CAC) scores determined before the start of whole breast irradiation with those determined 3 years afterwards. Changes in CAC scores were analysed in 99 breast cancer patients. Three groups were compared: patients receiving left- and right-sided radiotherapy, and those receiving left-sided radiotherapy with breath-hold. We analysed overall CAC scores and left anterior descending (LAD) and right coronary artery (RCA) CAC scores. Between the three groups, changes of the value of the LAD minus the RCA CAC scores of each individual patient were also compared. Three years after breath-hold-based whole breast irradiation, a less pronounced increase of CAC scores was noted. Furthermore, LAD minus RCA scores in patients treated for left-sided breast cancer without breath-hold were higher when compared to LAD minus RCA scores of patients with right-sided breast cancers and those with left-sided breast cancer treated with breath-hold. Breath-hold in breast-conserving radiotherapy leads to a less pronounced increase of CT-based CAC scores. Therefore, breath-hold probably prevents the development of radiation-induced coronary artery disease. However, the sample size of this study is limited and the follow-up period relatively short. (orig.) [German] Das Ziel dieser prospektiven Langzeitstudie war der Vergleich der Coronary-Artery-Calcium-(CAC-)Werte vor Beginn der Brustbestrahlung mit den Werten nach 3 Jahren. Aenderungen der CAC-Werte wurden bei 99 Brustkrebspatienten analysiert. Drei Gruppen wurden untersucht: Patienten nach links- und rechtsseitiger Strahlentherapie sowie mit Bestrahlung unter Atemanhalt. Wir analysierten die Gesamt-CAC-Werte sowie die CAC-Werte der vorderen linken absteigenden (''left anterior descending'', LAD) und der rechten Koronararterie (''right coronary artery'', RCA). Zwischen den drei Gruppen wurden auch die Veraenderungen

  11. Doing HOF work in NPP - an internal specialist point of view

    International Nuclear Information System (INIS)

    Koistinen, Petri

    2011-01-01

    Organisational learning has been identified as one success factor both in general business literature and also in nuclear industry. One part of organisational learning is routines that support organisational learning. In nuclear industry learning from events is an important process of organisational learning. The other building blocks of learning organisation are climate that supports learning and leadership that encourages learning. These have also been identified in nuclear industry as being important issues. Learning from events relies on the validity of the investigation process. Investigation process and report has simply three parts: what happened (facts), why it happened (analysis) and how to prevent reoccurrence (corrective actions, CA). In RCA analysis part is highlighted, however it cannot be done correctly unless the facts have not been collected well. In a good learning process there must also be a follow up and feedback system for CA's. The following are the key points from this presentation: - Koistinen has been an internal HOF specialist since 2004; still the only HOF specialist at TVO. - Main duties are event investigations (including RCA), operating experience, safety culture improvement, human performance and organisational development issues. - Human error is typically the end point of an investigation - Koistinen's job is to find out what has led a good professional to make an error (organisational factors). - A blame-free or just culture is required to identify the organisational issues in an event. - RCA is used for the most serious events - about 5 RCA like investigations are conducted at the two TVO units per year. - Finland does not have RCA training available and so staff must go elsewhere. Those working in event investigations are usually new in the nuclear business and therefore lack experience. - The author presents a number of guidelines from STUK, the Finnish regulatory body. There are requirements for competence of investigators

  12. Overview of studies on the effect of recycled aggregates sourced from tested cylinders on concrete material and structural properties

    Directory of Open Access Journals (Sweden)

    Bilal Hamad

    2017-01-01

    Full Text Available The paper presents an overview of a two-phase research program that was designed at the American University of Beirut (AUB to investigate the effect of replacing different percentages of natural coarse aggregates (NCA with recycled coarse aggregates (RCA on the properties of the produced concrete. The source of RCA was tested cylinders in batching plants which would help recycling and reusing portion of the waste products of the concrete industry. In the first phase, the fresh and hardened mechanical properties of the produced concrete mix were investigated. The variables were the concrete strength (28 or 60 MPa and the percentage replacement of NCA with RCA from crushed tested cylinders [0 (control, 20, 40, 60, 80, or 100%. Normal strength tested cylinders were used as source of the recycled aggregates for the normal strength concrete (NSC mix and high strength tested cylinders were used for the high strength concrete (HSC mix. Tests included plastic state slump and hardened state mechanical properties including cylinder compressive strength, cylinder splitting tensile strength, modulus of elasticity, and standard beams flexural strength. The results indicated no significant effect on the slump and around 10% average reduction in the hardened mechanical properties for both investigated levels of concrete compressive strength. In the second phase, the structural behavior of normal strength concrete (NSC reinforced concrete beams prepared by replacing different percentages of NCA with RCA from tested concrete cylinders was studied. For each of three modes of failure (flexural, shear, or bond splitting, three beams with different percentages replacement [0 (control, 40, or 100 percent] were tested. One replicate was prepared for each beam to validate the test results. Results indicated no significant difference in the ultimate load reached or load-deflection behavior that could be related to the percentage replacement of NCA with RCA.

  13. Root Cause Analysis Following an Event at a Nuclear Installation: Reference Manual

    International Nuclear Information System (INIS)

    2015-01-01

    Following an event at a nuclear installation, it is important to determine accurately its root causes so that effective corrective actions can be implemented. As stated in IAEA Safety Standards Series No. SF-1, Fundamental Safety Principles: “Processes must be put in place for the feedback and analysis of operating experience”. If this process is completed effectively, the probability of a similar event occurring is significantly reduced. Guidance on how to establish and implement such a process is given in IAEA Safety Standards Series No. NS-G-2.11, A System for the Feedback of Experience from Events in Nuclear Installations. To cater for the diverse nature of operating experience events, several different root cause analysis (RCA) methodologies and techniques have been developed for effective investigation and analysis. An event here is understood as any unanticipated sequence of occurrences that results in, or potentially results in, consequences to plant operation and safety. RCA is not a topic uniquely relevant to event investigators: knowledge of the concepts enhances the learning characteristics of the whole organization. This knowledge also makes a positive contribution to nuclear safety and helps to foster a culture of preventing event occurrence. This publication allows organizations to deepen their knowledge of these methodologies and techniques and also provides new organizations with a broad overview of the RCA process. It is the outcome of a coordinated effort involving the participation of experts from nuclear organizations, the energy industry and research centres in several Member States. This publication also complements IAEA Services Series No. 10, PROSPER Guidelines: Guidelines for Peer Review and for Plant Self- Assessment of Operational Experience Feedback Process, and is intended to form part of a suite of publications developing the principles set forth in these guidelines. In addition to the information and description of RCA

  14. Training the next generation analyst using red cell analytics

    Science.gov (United States)

    Graham, Meghan N.; Graham, Jacob L.

    2016-05-01

    We have seen significant change in the study and practice of human reasoning in recent years from both a theoretical and methodological perspective. Ubiquitous communication coupled with advances in computing and a plethora of analytic support tools have created a push for instantaneous reporting and analysis. This notion is particularly prevalent in law enforcement, emergency services and the intelligence community (IC), where commanders (and their civilian leadership) expect not only a birds' eye view of operations as they occur, but a play-by-play analysis of operational effectiveness. This paper explores the use of Red Cell Analytics (RCA) as pedagogy to train the next-gen analyst. A group of Penn State students in the College of Information Sciences and Technology at the University Park campus of The Pennsylvania State University have been practicing Red Team Analysis since 2008. RCA draws heavily from the military application of the same concept, except student RCA problems are typically on non-military in nature. RCA students utilize a suite of analytic tools and methods to explore and develop red-cell tactics, techniques and procedures (TTPs), and apply their tradecraft across a broad threat spectrum, from student-life issues to threats to national security. The strength of RCA is not always realized by the solution but by the exploration of the analytic pathway. This paper describes the concept and use of red cell analytics to teach and promote the use of structured analytic techniques, analytic writing and critical thinking in the area of security and risk and intelligence training.

  15. Isolation of Resistance Gene Candidates (RGCs) and characterization of an RGC cluster in cassava.

    Science.gov (United States)

    López, C E; Zuluaga, A P; Cooke, R; Delseny, M; Tohme, J; Verdier, V

    2003-08-01

    Plant disease resistance genes (R genes) show significant similarity amongst themselves in terms of both their DNA sequences and structural motifs present in their protein products. Oligonucleotide primers designed from NBS (Nucleotide Binding Site) domains encoded by several R-genes have been used to amplify NBS sequences from the genomic DNA of various plant species, which have been called Resistance Gene Analogues (RGAs) or Resistance Gene Candidates (RGCs). Using specific primers from the NBS and TIR (Toll/Interleukin-1 Receptor) regions, we identified twelve classes of RGCs in cassava (Manihot esculenta Crantz). Two classes were obtained from the PCR-amplification of the TIR domain. The other 10 classes correspond to the NBS sequences and were grouped into two subfamilies. Classes RCa1 to RCa5 are part of the first subfamily and were linked to a TIR domain in the N terminus. Classes RCa6 to RCa10 corresponded to non-TIR NBS-LRR encoding sequences. BAC library screening with the 12 RGC classes as probes allowed the identification of 42 BAC clones that were assembled into 10 contigs and 19 singletons. Members of the two TIR and non-TIR NBS-LRR subfamilies occurred together within individual BAC clones. The BAC screening and Southern hybridization analyses showed that all RGCs were single copy sequences except RCa6 that represented a large and diverse gene family. One BAC contained five NBS sequences and sequence analysis allowed the identification of two complete RGCs encoding two highly similar proteins. This BAC was located on linkage group J with three other RGC-containing BACs. At least one of these genes, RGC2, is expressed constitutively in cassava tissues.

  16. Testing and Results of Vacuum Swing Adsorption Units for Spacesuit Carbon Dioxide and Humidity Control

    Science.gov (United States)

    McMillin, Summer D.; Broerman, Craig D.; Swickrath, Michael; Anderson, Molly

    2011-01-01

    A principal concern for extravehicular activity (EVA) spacesuits is the capability to control carbon dioxide (CO2) and humidity (H2O) for the crewmember. The release of CO2 in a confined or unventilated area is dangerous for human health and leads to asphyxiation; therefore, CO2 and H2O control become leading factors in the design and development of the spacesuit. An amine-based CO2 and H2O vapor sorbent for use in pressure-swing regenerable beds has been developed by Hamilton Sundstrand. The application of solidamine materials with vacuum swing adsorption technology has shown the capacity to concurrently manage CO2 and H2O levels through a fully regenerative cycle eliminating mission constraints imposed with nonregenerative technologies. Two prototype solid amine-based systems, known as rapid cycle amine (RCA), were designed to continuously remove CO2 and H2O vapor from a flowing ventilation stream through the use of a two-bed amine based, vacuum-swing adsorption system. The Engineering and Science Contract Group (ESCG) RCA implements radial flow paths, whereas the Hamilton Sundstrand RCA was designed with linear flow paths. Testing was performed in a sea-level pressure environment and a reduced-pressure environment with simulated human metabolic loads in a closed-loop configuration. This paper presents the experimental results of laboratory testing for a full-size and a sub-scale test article. The testing described here characterized and evaluated the performance of each RCA unit at the required Portable Life Support Subsystem (PLSS) operating conditions. The test points simulated a range of crewmember metabolic rates. The experimental results demonstrated the ability of each RCA unit to sufficiently remove CO2 and H2O from a closed loop ambient or sub-ambient atmosphere.

  17. Root Cause Analysis Following an Event at a Nuclear Installation: Reference Manual. Companion CD

    International Nuclear Information System (INIS)

    2015-01-01

    Following an event at a nuclear installation, it is important to determine accurately its root causes so that effective corrective actions can be implemented. As stated in IAEA Safety Standards Series No. SF-1, Fundamental Safety Principles: “Processes must be put in place for the feedback and analysis of operating experience”. If this process is completed effectively, the probability of a similar event occurring is significantly reduced. Guidance on how to establish and implement such a process is given in IAEA Safety Standards Series No. NS-G-2.11, A System for the Feedback of Experience from Events in Nuclear Installations. To cater for the diverse nature of operating experience events, several different root cause analysis (RCA) methodologies and techniques have been developed for effective investigation and analysis. An event here is understood as any unanticipated sequence of occurrences that results in, or potentially results in, consequences to plant operation and safety. RCA is not a topic uniquely relevant to event investigators: knowledge of the concepts enhances the learning characteristics of the whole organization. This knowledge also makes a positive contribution to nuclear safety and helps to foster a culture of preventing event occurrence. This publication allows organizations to deepen their knowledge of these methodologies and techniques and also provides new organizations with a broad overview of the RCA process. It is the outcome of a coordinated effort involving the participation of experts from nuclear organizations, the energy industry and research centres in several Member States. This publication also complements IAEA Services Series No. 10, PROSPER Guidelines: Guidelines for Peer Review and for Plant Self- Assessment of Operational Experience Feedback Process, and is intended to form part of a suite of publications developing the principles set forth in these guidelines. In addition to the information and description of RCA

  18. POSISI DAYA SAING DAN FAKTOR-FAKTOR YANG MEMENGARUHI EKSPOR BUAH-BUAHAN INDONESIA

    Directory of Open Access Journals (Sweden)

    Amalia Pradipta

    2015-02-01

    Full Text Available The success of competitiveness of Indonesian fruits export in the destination countries is determined by comparative and competitive advantage and other factors. Revealed Comparative Advantage (RCA and Export Product Dynamic (EPD are used in this research to analyze the position of competitiveness of Indonesian fruits export. This research also uses panel gravity model to analyze the factors which affect the export volume of Indonesia fruits (mango, mangosteen, rambutan, banana, and melon. The results from EPD and RCA method show that fruits which have the highest comparative and competitive advantage in destination countries and the world are mangoesteen, mango, and guava. Indonesian fruit which lost its opportunity to compete in the destination countries is strawberry. The results of this research shows that the factors which influence the export of Indonesian fruits to the destination countries are export price, population, economic distance, real GDP and GDP per capita, real exchange rate, Indonesian consumer price index, and dummy variable of crisis which happened in Europe.Keywords: competitiveness, EPD, gravity model, RCAABSTRAKKeberhasilan daya saing ekspor buah Indonesia di negara tujuan ditentukan oleh keunggulan komparatif dan kompetitif serta faktor lainnya. Revealed Comparative Advantage (RCA dan Export Product Dynamic (EPD digunakan untuk menganalisis posisi daya saing ekspor buah-buahan Indonesia. Pada penelitian ini digunakan analisis data panel gravity model untuk menganalisis faktor-faktor yang memengaruhi aliran volume ekspor buah-buahan Indonesia (mangga, manggis, rambutan, pisang, dan melon. Pada metode Export Product Dynamic (EPD dan Revealed Comparative Advantage (RCA menunjukkan bahwa buah yang memiliki keunggulan komparatif dan kompetitif tertinggi di negara tujuan dan dunia adalah buah manggis, mangga, dan jambu. Ekspor buah Indonesia yang kehilangan kesempatan dalam bersaing di negara tujuan adalah stroberi. Hasil

  19. Analytically Sensitive Protein Detection in Microtiter Plates by Proximity Ligation with Rolling Circle Amplification.

    Science.gov (United States)

    Ebai, Tonge; Souza de Oliveira, Felipe Marques; Löf, Liza; Wik, Lotta; Schweiger, Caroline; Larsson, Anders; Keilholtz, Ulrich; Haybaeck, Johannes; Landegren, Ulf; Kamali-Moghaddam, Masood

    2017-09-01

    Detecting proteins at low concentrations in plasma is crucial for early diagnosis. Current techniques in clinical routine, such as sandwich ELISA, provide sensitive protein detection because of a dependence on target recognition by pairs of antibodies, but detection of still lower protein concentrations is often called for. Proximity ligation assay with rolling circle amplification (PLARCA) is a modified proximity ligation assay (PLA) for analytically specific and sensitive protein detection via binding of target proteins by 3 antibodies, and signal amplification via rolling circle amplification (RCA) in microtiter wells, easily adapted to instrumentation in use in hospitals. Proteins captured by immobilized antibodies were detected using a pair of oligonucleotide-conjugated antibodies. Upon target recognition these PLA probes guided oligonucleotide ligation, followed by amplification via RCA of circular DNA strands that formed in the reaction. The RCA products were detected by horseradish peroxidase-labeled oligonucleotides to generate colorimetric reaction products with readout in an absorbance microplate reader. We compared detection of interleukin (IL)-4, IL-6, IL-8, p53, and growth differentiation factor 15 (GDF-15) by PLARCA and conventional sandwich ELISA or immuno-RCA. PLARCA detected lower concentrations of proteins and exhibited a broader dynamic range compared to ELISA and iRCA using the same antibodies. IL-4 and IL-6 were detected in clinical samples at femtomolar concentrations, considerably lower than for ELISA. PLARCA offers detection of lower protein levels and increased dynamic ranges compared to ELISA. The PLARCA procedure may be adapted to routine instrumentation available in hospitals and research laboratories. © 2017 American Association for Clinical Chemistry.

  20. Community Laboratory Testing for Cryptosporidium: Multicenter Study Retesting Public Health Surveillance Stool Samples Positive for Cryptosporidium by Rapid Cartridge Assay with Direct Fluorescent Antibody Testing.

    Directory of Open Access Journals (Sweden)

    Dawn M Roellig

    Full Text Available Cryptosporidium is a common cause of sporadic diarrheal disease and outbreaks in the United States. Increasingly, immunochromatography-based rapid cartridge assays (RCAs are providing community laboratories with a quick cryptosporidiosis diagnostic method. In the current study, the Centers for Disease Control and Prevention (CDC, the Association of Public Health Laboratories (APHL, and four state health departments evaluated RCA-positive samples obtained during routine Cryptosporidium testing. All samples underwent "head to head" re-testing using both RCA and direct fluorescence assay (DFA. Community level results from three sites indicated that 54.4% (166/305 of Meridian ImmunoCard STAT! positives and 87.0% (67/77 of Remel Xpect positives were confirmed by DFA. When samples were retested by RCA at state laboratories and compared with DFA, 83.3% (155/186 of Meridian ImmunoCard STAT! positives and 95.2% (60/63 of Remel Xpect positives were confirmed. The percentage of confirmed community results varied by site: Minnesota, 39.0%; New York, 63.9%; and Wisconsin, 72.1%. The percentage of confirmed community results decreased with patient age; 12.5% of community positive tests could be confirmed by DFA for patients 60 years of age or older. The percentage of confirmed results did not differ significantly by sex, storage temperature, time between sample collection and testing, or season. Findings from this study demonstrate a lower confirmation rate of community RCA positives when compared to RCA positives identified at state laboratories. Elucidating the causes of decreased test performance in order to improve overall community laboratory performance of these tests is critical for understanding the epidemiology of cryptosporidiosis in the United States (US.