WorldWideScience

Sample records for fr30jn10r temporary suspension

  1. 22 CFR 126.2 - Temporary suspension or modification of this subchapter.

    Science.gov (United States)

    2010-04-01

    ... subchapter. 126.2 Section 126.2 Foreign Relations DEPARTMENT OF STATE INTERNATIONAL TRAFFIC IN ARMS REGULATIONS GENERAL POLICIES AND PROVISIONS § 126.2 Temporary suspension or modification of this subchapter. The Deputy Assistant Secretary for Defense Trade Controls or the Managing Director, Directorate of...

  2. 32 CFR 147.30 - Temporary eligibility for access at the confidential and secret levels and temporary eligibility...

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 1 2010-07-01 2010-07-01 false Temporary eligibility for access at the confidential and secret levels and temporary eligibility for âLâ access authorization. 147.30 Section 147.30... Temporary Access § 147.30 Temporary eligibility for access at the confidential and secret levels and...

  3. 30 CFR 47.44 - Temporary, portable containers.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Temporary, portable containers. 47.44 Section... TRAINING HAZARD COMMUNICATION (HazCom) Container Labels and Other Forms of Warning § 47.44 Temporary, portable containers. (a) The operator does not have to label a temporary, portable container if he or she...

  4. 75 FR 11627 - Order Granting Temporary Exemptions From Certain Government Securities Act Provisions and...

    Science.gov (United States)

    2010-03-11

    ... DEPARTMENT OF THE TREASURY Order Granting Temporary Exemptions From Certain Government Securities... Department of the Treasury (Treasury) is granting temporary exemptions from certain Government Securities Act...).pdf. \\8\\ 75 FR 4626, January 28, 2010 Order Granting a Temporary Exemption from Certain Government...

  5. 30 CFR 75.209 - Automated Temporary Roof Support (ATRS) systems.

    Science.gov (United States)

    2010-07-01

    ... of temporary support shall be used, as specified in the roof control plan, when— (1) Mining... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Automated Temporary Roof Support (ATRS) systems... COAL MINE SAFETY AND HEALTH MANDATORY SAFETY STANDARDS-UNDERGROUND COAL MINES Roof Support § 75.209...

  6. Temporary suspension of acute facial paralysis using the S-S Cable Suture (Medical U&A, Tokyo, Japan).

    Science.gov (United States)

    Ozaki, Mine; Takushima, Akihiko; Momosawa, Akira; Kurita, Masakazu; Harii, Kiyonori

    2008-07-01

    For a treatment of facial paralysis, suture suspension of soft tissue is considered effective due to its less invasiveness and relatively simple technique, with minimal bruising and rapid recovery. However, suture suspension effect may not last for a long period of time. We obtained good outcome with temporary static suture suspension in 5 cases of severe facial paralysis in the intervening period between the onset of paralysis and expected spontaneous recovery. We used the S-S Cable Suture (Medical U&A, Tokyo, Japan), which was based on the modification of previously established method using the Gore-Tex cable suture originally reported by Sasaki et al in 2002. Because of the ease of technique and relatively strong lifting capability of the malar pad, we recommend it as a useful procedure for a patient suffering acute facial paralysis with possible spontaneous recovery for an improved quality of life by the quick elimination of facial distortion.

  7. 31 CFR 357.30 - Cases of delay or suspension of payment.

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 2 2010-07-01 2010-07-01 false Cases of delay or suspension of payment. 357.30 Section 357.30 Money and Finance: Treasury Regulations Relating to Money and Finance... Securities System (Legacy Treasury Direct) § 357.30 Cases of delay or suspension of payment. If evidence...

  8. 77 FR 24225 - Information Collection Approval; Temporary Non-Agricultural Employment of H-2B Aliens in the...

    Science.gov (United States)

    2012-04-23

    ... DEPARTMENT OF LABOR Employment and Training Administration Information Collection Approval; Temporary Non-Agricultural Employment of H-2B Aliens in the United States AGENCY: Employment and Training... the Temporary Non-Agricultural Employment of H-2B Aliens in the United States; Final Rule. See 77 FR...

  9. 30 CFR 816.14 - Casing and sealing of drilled holes: Temporary.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 3 2010-07-01 2010-07-01 false Casing and sealing of drilled holes: Temporary. 816.14 Section 816.14 Mineral Resources OFFICE OF SURFACE MINING RECLAMATION AND ENFORCEMENT...-SURFACE MINING ACTIVITIES § 816.14 Casing and sealing of drilled holes: Temporary. Each exploration hole...

  10. 30 CFR 203.73 - How do suspension volumes apply to natural gas?

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false How do suspension volumes apply to natural gas... suspension volumes apply to natural gas? You must measure natural gas production under the royalty-suspension volume as follows: 5.62 thousand cubic feet of natural gas, measured in accordance with 30 CFR part 250...

  11. A viable logarithmic f(R) model for inflation

    Energy Technology Data Exchange (ETDEWEB)

    Amin, M.; Khalil, S. [Center for Fundamental Physics, Zewail City of Science and Technology,6 October City, Giza (Egypt); Salah, M. [Center for Fundamental Physics, Zewail City of Science and Technology,6 October City, Giza (Egypt); Department of Mathematics, Faculty of Science, Cairo University,Giza (Egypt)

    2016-08-18

    Inflation in the framework of f(R) modified gravity is revisited. We study the conditions that f(R) should satisfy in order to lead to a viable inflationary model in the original form and in the Einstein frame. Based on these criteria we propose a new logarithmic model as a potential candidate for f(R) theories aiming to describe inflation consistent with observations from Planck satellite (2015). The model predicts scalar spectral index 0.9615r of order 10{sup −3}. Furthermore, we show that for a class of models, a natural coupling between inflation and a scalar boson is generated through the minimal coupling between gravity and matter fields and a reheating temperature less that 10{sup 9} GeV is obtained.

  12. Future dynamics in f(R) theories

    International Nuclear Information System (INIS)

    Mueller, D.; Andrade, V.C. de; Maia, C.; Reboucas, M.J.; Teixeira, A.F.F.

    2015-01-01

    The f(R) gravity theories provide an alternative way to explain the current cosmic acceleration without invoking a dark energy matter component used in the cosmological modeling in the framework of general relativity. However, the freedom in the choice of the functional forms of f(R) gives rise to the problem of the degeneracy among these gravity theories on theoretical and (or) observational grounds. In this paper we examine the question as to whether the future dynamics can be used to break the degeneracy between f(R) gravity theories by investigating the dynamics of spatially homogeneous and isotropic dust flat models in two f(R) gravity theories, namely the well known f(R) = R+αR n gravity and another byAviles et al., whose motivation comes from the cosmographic approach to f(R) gravity. We perform a detailed numerical study of the dynamics of these theories taking into account the recent constraints on the cosmological parameters made by the Planck Collaboration. We demonstrate that besides being useful for discriminating between these two f(R) gravity theories, the future dynamics technique can also be used to determine the finite-time behavior as well as the fate of the Universe in the framework of these f(R) gravity theories. There also emerges from our analysis the result that one still can have a dust flat FLRWsolution with a big rip, if gravity is governed by f(R) = R+αR n . We also show that FLRW dust solutions with f'' < 0 do not necessarily lead to singularities. (orig.)

  13. 36 CFR 296.10 - Suspension and revocation of permits.

    Science.gov (United States)

    2010-07-01

    ... AGRICULTURE PROTECTION OF ARCHAEOLOGICAL RESOURCES: UNIFORM REGULATIONS § 296.10 Suspension and revocation of... correct the situation which led to suspension of the permit. (b) Suspension or revocation for management...

  14. 78 FR 24239 - Temporary Mailing Promotion

    Science.gov (United States)

    2013-04-24

    ... POSTAL REGULATORY COMMISSION [Docket No. R2013-6; Order No. 1702] Temporary Mailing Promotion... offering a Technology Credit Promotion. This notice informs the public of the Postal Service's filing and... changes associated with offering a Technology Credit Promotion.\\1\\ The promotion is planned to begin on...

  15. 40 CFR 310.10 - What are temporary emergency measures?

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 27 2010-07-01 2010-07-01 false What are temporary emergency measures... RESPONSE TO HAZARDOUS SUBSTANCE RELEASES Provisions What Can Be Reimbursed? § 310.10 What are temporary... security; (2) Controlling the source of contamination; (3) Containing the release to prevent spreading; (4...

  16. 48 CFR 37.112 - Government use of private sector temporaries.

    Science.gov (United States)

    2010-10-01

    ... use of private sector temporaries. Contracting officers may enter into contracts with temporary help service firms for the brief or intermittent use of the skills of private sector temporaries. Services... part 300, subpart E, Use of Private Sector Temporaries, and agency procedures. [56 FR 55380, Oct. 25...

  17. 75 FR 61352 - Airworthiness Directives; McDonnell Douglas Corporation Model DC-10-30, DC-10-30F, DC-10-30F (KC...

    Science.gov (United States)

    2010-10-05

    ... Airworthiness Directives; McDonnell Douglas Corporation Model DC- 10-30, DC-10-30F, DC-10-30F (KC-10A and KDC-10...-13 McDonnell Douglas Corporation: Amendment 39-16448; Docket No. FAA-2010-0553; Directorate.... Applicability (c) This AD applies to McDonnell Douglas Corporation Model DC- 10-30, DC-10-30F, DC-10-30F (KC-10A...

  18. 46 CFR 30.10-50 - Pilot boarding equipment and point of access.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 1 2010-10-01 2010-10-01 false Pilot boarding equipment and point of access. 30.10-50... Definitions § 30.10-50 Pilot boarding equipment and point of access. (a) Pilot boarding equipment means a... boarding equipment. [CGD 79-032, 49 FR 25455, June 21, 1984] ...

  19. Galaxy-galaxy weak gravitational lensing in f(R) gravity

    Science.gov (United States)

    Li, Baojiu; Shirasaki, Masato

    2018-03-01

    We present an analysis of galaxy-galaxy weak gravitational lensing (GGL) in chameleon f(R) gravity - a leading candidate of non-standard gravity models. For the analysis, we have created mock galaxy catalogues based on dark matter haloes from two sets of numerical simulations, using a halo occupation distribution (HOD) prescription which allows a redshift dependence of galaxy number density. To make a fairer comparison between the f(R) and Λ cold dark matter (ΛCDM) models, their HOD parameters are tuned so that the galaxy two-point correlation functions in real space (and therefore the projected two-point correlation functions) match. While the f(R) model predicts an enhancement of the convergence power spectrum by up to ˜ 30 per cent compared to the standard ΛCDM model with the same parameters, the maximum enhancement of GGL is only half as large and less than 5 per cent on separations above ˜1-2 h-1 Mpc, because the latter is a cross-correlation of shear (or matter, which is more strongly affected by modified gravity) and galaxy (which is weakly affected given the good match between galaxy autocorrelations in the two models) fields. We also study the possibility of reconstructing the matter power spectrum by combination of GGL and galaxy clustering in f(R) gravity. We find that the galaxy-matter cross-correlation coefficient remains at unity down to ˜2-3 h-1 Mpc at relevant redshifts even in f(R) gravity, indicating joint analysis of GGL and galaxy clustering can be a powerful probe of matter density fluctuations in chameleon gravity. The scale dependence of the model differences in their predictions of GGL can potentially allows us to break the degeneracy between f(R) gravity and other cosmological parameters such as Ωm and σ8.

  20. 76 FR 46216 - Federal Travel Regulation (FTR): Temporary Duty (TDY) Travel Allowances: Notice of Public Meeting...

    Science.gov (United States)

    2011-08-02

    ...; Sequence 5] Federal Travel Regulation (FTR): Temporary Duty (TDY) Travel Allowances: Notice of Public... and the general public in an effort to streamline travel policies, incorporated travel efficiency and.... Flynn, Deputy Director, Office of Travel, Transportation & Asset Management. [FR Doc. 2011-19482 Filed 8...

  1. Physical attributes of anisotropic compact stars in f(R, G) gravity

    Energy Technology Data Exchange (ETDEWEB)

    Shamir, M.F.; Zia, Saeeda [National University of Computer and Emerging Sciences, Department of Sciences and Humanities, Lahore (Pakistan)

    2017-07-15

    Modified gravity is one of the potential candidates to explain the accelerated expansion of the universe. Current study highlights the materialization of anisotropic compact stars in the context of f(R, G) theory of gravity. In particular, to gain insight in the physical behavior of three stars namely, Her X1, SAX J 1808-3658 and 4U 1820-30, energy density, and radial and tangential pressures are calculated. The f(R, G) gravity model is split into a Starobinsky like f(R) model and a power law f(G) model. The main feature of the work is a 3-dimensional graphical analysis in which, anisotropic measurements, energy conditions and stability attributes of these stars are discussed. It is shown that all three stars behave as usual for positive values of the f(G) model parameter n. (orig.)

  2. f(R) gravity solutions for evolving wormholes

    Energy Technology Data Exchange (ETDEWEB)

    Bhattacharya, Subhra [Presidency University, Department of Mathematics, Kolkata (India); Chakraborty, Subenoy [Jadavpur University, Department of Mathematics, Kolkata (India)

    2017-08-15

    The scalar-tensor f(R) theory of gravity is considered in the framework of a simple inhomogeneous space-time model. In this research we use the reconstruction technique to look for possible evolving wormhole solutions within viable f(R) gravity formalism. These f(R) models are then constrained so that they are consistent with existing experimental data. Energy conditions related to the matter threading the wormhole are analyzed graphically and are in general found to obey the null energy conditions (NEC) in regions around the throat, while in the limit f(R) = R, NEC can be violated at large in regions around the throat. (orig.)

  3. 78 FR 35351 - Polar Petroleum Corp.; Order of Suspension of Trading

    Science.gov (United States)

    2013-06-12

    ... Trading June 10, 2013. It appears to the Securities and Exchange Commission that there is a lack of... the protection of investors require a suspension of trading in the securities of the above-listed... trading in the securities of the above-listed company is suspended for the period from 9:30 a.m. EDT on...

  4. Exploring plane-symmetric solutions in f(R) gravity

    Energy Technology Data Exchange (ETDEWEB)

    Shamir, M. F., E-mail: farasat.shamir@nu.edu.pk [National University of Computer and Emerging Sciences, Department of Sciences and Humanities (Pakistan)

    2016-02-15

    The modified theories of gravity, especially the f(R) gravity, have attracted much attention in the last decade. This paper is devoted to exploring plane-symmetric solutions in the context of metric f(R) gravity. We extend the work on static plane-symmetric vacuum solutions in f(R) gravity already available in the literature [1, 2]. The modified field equations are solved using the assumptions of both constant and nonconstant scalar curvature. Some well-known solutions are recovered with power-law and logarithmic forms of f(R) models.

  5. 76 FR 65360 - Irish Potatoes Grown in Southeastern States; Suspension of Marketing Order Provisions

    Science.gov (United States)

    2011-10-21

    ... operate without marketing order requirements in order to review the effectiveness of the order. During the... DEPARTMENT OF AGRICULTURE Agricultural Marketing Service 7 CFR Part 953 [Doc. No. AMS-FV-11-0027; FV11-953-1 FR] Irish Potatoes Grown in Southeastern States; Suspension of Marketing Order Provisions...

  6. Disentangling the f(R). Duality

    International Nuclear Information System (INIS)

    Broy, Benedict J.; Westphal, Alexander; Pedro, Francisco G.; Univ. Autonoma de Madrid

    2014-11-01

    Motivated by UV realisations of Starobinsky-like inflation models, we study generic exponential plateau-like potentials to understand whether an exact f(R)-formulation may still be obtained when the asymptotic shift-symmetry of the potential is broken for larger field values. Potentials which break the shift symmetry with rising exponentials at large field values only allow for corresponding f(R)-descriptions with a leading order term R n with 1 2 -term survives as part of a series expansion of the function f(R) and thus cannot maintain a plateau for all field values. We further find a lean and instructive way to obtain a function f(R) describing m 2 φ 2 -inflation which breaks the shift symmetry with a monomial, and corresponds to effectively logarithmic corrections to an R+R 2 model. These examples emphasise that higher order terms in f(R)-theory may not be neglected if they are present at all. Additionally, we relate the function f(R) corresponding to chaotic inflation to a more general Jordan frame set-up. In addition, we consider f(R)-duals of two given UV examples, both from supergravity and string theory. Finally, we outline the CMB phenomenology of these models which show effects of power suppression at low-l.

  7. Geodesic congruences in the Palatini f(R) theory

    International Nuclear Information System (INIS)

    Shojai, Fatimah; Shojai, Ali

    2008-01-01

    We shall investigate the properties of a congruence of geodesics in the framework of Palatini f(R) theories. We shall evaluate the modified geodesic deviation equation and the Raychaudhuri's equation and show that f(R) Palatini theories do not necessarily lead to attractive forces. Also, we shall study energy condition for f(R) Palatini gravity via a perturbative analysis of the Raychaudhuri's equation.

  8. Clustering of galaxies with f(R) gravity

    Science.gov (United States)

    Capozziello, Salvatore; Faizal, Mir; Hameeda, Mir; Pourhassan, Behnam; Salzano, Vincenzo; Upadhyay, Sudhaker

    2018-02-01

    Based on thermodynamics, we discuss the galactic clustering of expanding Universe by assuming the gravitational interaction through the modified Newton's potential given by f(R) gravity. We compute the corrected N-particle partition function analytically. The corrected partition function leads to more exact equations of state of the system. By assuming that the system follows quasi-equilibrium, we derive the exact distribution function that exhibits the f(R) correction. Moreover, we evaluate the critical temperature and discuss the stability of the system. We observe the effects of correction of f(R) gravity on the power-law behaviour of particle-particle correlation function also. In order to check the feasibility of an f(R) gravity approach to the clustering of galaxies, we compare our results with an observational galaxy cluster catalogue.

  9. Nonlinear evolution of f(R) cosmologies. I. Methodology

    International Nuclear Information System (INIS)

    Oyaizu, Hiroaki

    2008-01-01

    We introduce the method and the implementation of a cosmological simulation of a class of metric-variation f(R) models that accelerate the cosmological expansion without a cosmological constant and evade solar-system bounds of small-field deviations to general relativity. Such simulations are shown to reduce to solving a nonlinear Poisson equation for the scalar degree of freedom introduced by the f(R) modifications. We detail the method to efficiently solve the nonlinear Poisson equation by using a Newton-Gauss-Seidel relaxation scheme coupled with the multigrid method to accelerate the convergence. The simulations are shown to satisfy tests comparing the simulated outcome to analytical solutions for simple situations, and the dynamics of the simulations are tested with orbital and Zeldovich collapse tests. Finally, we present several static and dynamical simulations using realistic cosmological parameters to highlight the differences between standard physics and f(R) physics. In general, we find that the f(R) modifications result in stronger gravitational attraction that enhances the dark matter power spectrum by ∼20% for large but observationally allowed f(R) modifications. A more detailed study of the nonlinear f(R) effects on the power spectrum are presented in a companion paper.

  10. Physical Exposures, Work Tasks, and OSHA-10 Training Among Temporary and Payroll Construction Workers.

    Science.gov (United States)

    Caban-Martinez, Alberto J; Santiago, Katerina M; Stillman, Jordan; Moore, Kevin J; Sierra, Danielle A; Chalmers, Juanita; Baniak, Melissa; Jordan, Melissa M

    2018-04-01

    We characterize and compare the self-reported physical exposures, work tasks, and OSHA-10 training in a non-probabilistic sample of temporary and payroll construction workers. In June 2016, a total of 250 payroll and temporary general laborers employed at Florida construction sites completed a survey at the job site as part of the falls reported among minority employees (FRAME) study. Workers employed through temp agencies (57.1%) were significantly more likely to report moving or lifting materials more than 100 pounds than payroll workers (38.5%; P < 0.01). Temporary construction workers with 10-hour OSHA training (22.2%) spent significantly less time with intense hand use/awkward hand posture than temporary workers without 10-hour OSHA training (46.9%; P = 0.048). Temp construction workers with OSHA 10-hour training reported less hazardous physical postures than workers without the same training.

  11. Solar System constraints to general f(R) gravity

    International Nuclear Information System (INIS)

    Chiba, Takeshi; Smith, Tristan L.; Erickcek, Adrienne L.

    2007-01-01

    It has been proposed that cosmic acceleration or inflation can be driven by replacing the Einstein-Hilbert action of general relativity with a function f(R) of the Ricci scalar R. Such f(R) gravity theories have been shown to be equivalent to scalar-tensor theories of gravity that are incompatible with Solar System tests of general relativity, as long as the scalar field propagates over Solar System scales. Specifically, the parameterized post-Newtonian (PPN) parameter in the equivalent scalar-tensor theory is γ=1/2, which is far outside the range allowed by observations. In response to a flurry of papers that questioned the equivalence of f(R) theory to scalar-tensor theories, it was recently shown explicitly, without resorting to the scalar-tensor equivalence, that the vacuum field equations for 1/R gravity around a spherically symmetric mass also yield γ=1/2. Here we generalize this analysis to f(R) gravity and enumerate the conditions that, when satisfied by the function f(R), lead to the prediction that γ=1/2

  12. f(R) gravity and chameleon theories

    International Nuclear Information System (INIS)

    Brax, Philippe; Bruck, Carsten van de; Davis, Anne-Christine; Shaw, Douglas J.

    2008-01-01

    We analyze f(R) modifications of Einstein's gravity as dark energy models in the light of their connection with chameleon theories. Formulated as scalar-tensor theories, the f(R) theories imply the existence of a strong coupling of the scalar field to matter. This would violate all experimental gravitational tests on deviations from Newton's law. Fortunately, the existence of a matter dependent mass and a thin-shell effect allows one to alleviate these constraints. The thin-shell condition also implies strong restrictions on the cosmological dynamics of the f(R) theories. As a consequence, we find that the equation of state of dark energy is constrained to be extremely close to -1 in the recent past. We also examine the potential effects of f(R) theories in the context of the Eoet-wash experiments. We show that the requirement of a thin shell for the test bodies is not enough to guarantee a null result on deviations from Newton's law. As long as dark energy accounts for a sizeable fraction of the total energy density of the Universe, the constraints that we deduce also forbid any measurable deviation of the dark energy equation of state from -1. All in all, we find that both cosmological and laboratory tests imply that f(R) models are almost coincident with a ΛCDM model at the background level.

  13. Stellar equilibrium configurations of white dwarfs in the f(R, T) gravity

    Energy Technology Data Exchange (ETDEWEB)

    Carvalho, G.A.; Moraes, P.H.R.S.; Marinho, R.M.; Malheiro, M. [Instituto Tecnologico de Aeronautica, Departamento de Fisica, Sao Jose dos Campos, SP (Brazil); Lobato, R.V. [Instituto Tecnologico de Aeronautica, Departamento de Fisica, Sao Jose dos Campos, SP (Brazil); Sapienza Universita di Roma, Dipartimento di Fisica, Rome (Italy); ICRANet, Pescara (Italy); Arbanil, Jose D.V. [Universidad Privada del Norte, Departamento de Ciencias, Lima (Peru); Otoniel, E. [Universidade Federal do Cariri, Instituto de Formacao de Professores, Brejo Santo, CE (Brazil)

    2017-12-15

    In this work we investigate the equilibrium configurations of white dwarfs in a modified gravity theory, namely, f(R, T) gravity, for which R and T stand for the Ricci scalar and trace of the energy-momentum tensor, respectively. Considering the functional form f(R, T) = R+2λT, with λ being a constant, we obtain the hydrostatic equilibrium equation for the theory. Some physical properties of white dwarfs, such as: mass, radius, pressure and energy density, as well as their dependence on the parameter λ are derived. More massive and larger white dwarfs are found for negative values of λ when it decreases. The equilibrium configurations predict a maximum mass limit for white dwarfs slightly above the Chandrasekhar limit, with larger radii and lower central densities when compared to standard gravity outcomes. The most important effect of f(R, T) theory for massive white dwarfs is the increase of the radius in comparison with GR and also f(R) results. By comparing our results with some observational data of massive white dwarfs we also find a lower limit for λ, namely, λ > -3 x 10{sup -4}. (orig.)

  14. 17 CFR Appendix A to Part 30 - Interpretative Statement With Respect to the Commission's Exemptive Authority Under § 30.10 of...

    Science.gov (United States)

    2010-04-01

    .... Sales Practice Standards. In 1982, Congress reaffirmed the importance of minimum sales practice... the sharing of information. Marketing Activities by Firms Granted Rule 30.10 Relief FR date and...

  15. Dynamics of anisotropic power-law f(R) cosmology

    International Nuclear Information System (INIS)

    Shamir, M. F.

    2016-01-01

    Modified theories of gravity have attracted much attention of the researchers in the recent years. In particular, the f(R) theory has been investigated extensively due to important f(R) gravity models in cosmological contexts. This paper is devoted to exploring an anisotropic universe in metric f(R) gravity. A locally rotationally symmetric Bianchi type I cosmological model is considered for this purpose. Exact solutions of modified field equations are obtained for a well-known f(R) gravity model. The energy conditions are also discussed for the model under consideration. The viability of the model is investigated via graphical analysis using the present-day values of cosmological parameters. The model satisfies null energy, weak energy, and dominant energy conditions for a particular range of the anisotropy parameter while the strong energy condition is violated, which shows that the anisotropic universe in f(R) gravity supports the crucial issue of accelerated expansion of the universe.

  16. Dynamics of anisotropic power-law f(R) cosmology

    Energy Technology Data Exchange (ETDEWEB)

    Shamir, M. F., E-mail: farasat.shamir@nu.edu.pk [National University of Computer and Emerging Sciences, Lahore Campus, Department of Sciences and Humanities (Pakistan)

    2016-12-15

    Modified theories of gravity have attracted much attention of the researchers in the recent years. In particular, the f(R) theory has been investigated extensively due to important f(R) gravity models in cosmological contexts. This paper is devoted to exploring an anisotropic universe in metric f(R) gravity. A locally rotationally symmetric Bianchi type I cosmological model is considered for this purpose. Exact solutions of modified field equations are obtained for a well-known f(R) gravity model. The energy conditions are also discussed for the model under consideration. The viability of the model is investigated via graphical analysis using the present-day values of cosmological parameters. The model satisfies null energy, weak energy, and dominant energy conditions for a particular range of the anisotropy parameter while the strong energy condition is violated, which shows that the anisotropic universe in f(R) gravity supports the crucial issue of accelerated expansion of the universe.

  17. Divergent Synthesis of Revised Apratoxin E, 30-epi-Apratoxin E, and 30S/30R-Oxoapratoxin E.

    Science.gov (United States)

    Mao, Zhuo-Ya; Si, Chang-Mei; Liu, Yi-Wen; Dong, Han-Qing; Wei, Bang-Guo; Lin, Guo-Qiang

    2017-10-20

    In this report, originally proposed apratoxin E (30S-7), revised apratoxin E (30R-7), and (30S)/(30R)-oxoapratoxin E (30S)-38/(30R)-38 were efficiently prepared by two synthetic methods. The chiral lactone 10, recycled from the degradation of saponin glycosides, was utilized to prepare the key nonpeptide fragment 9. Our alternative convergent assembly strategy was applied to the divergent synthesis of revised apratoxin E and its three analogues. Moreover, ring-closing metathesis (RCM) was for the first time found to be an efficient strategy for the macrocyclization of apratoxins.

  18. 75 FR 26646 - Oral Dosage Form New Animal Drugs; Orbifloxacin Suspension

    Science.gov (United States)

    2010-05-12

    .... The NADA provides for the veterinary prescription use of an oral suspension containing orbifloxacin... 12, 2010. FOR FURTHER INFORMATION CONTACT: Melanie R. Berson, Center for Veterinary Medicine (HFV-110..., filed NADA 141-305 that provides for veterinary prescription use of ORBAX (orbifloxacin) Oral Suspension...

  19. Cosmology of f(R) gravity in the metric variational approach

    Science.gov (United States)

    Li, Baojiu; Barrow, John D.

    2007-04-01

    We consider the cosmologies that arise in a subclass of f(R) gravity with f(R)=R+μ2n+2/(-R)n and n∈(-1,0) in the metric (as opposed to the Palatini) variational approach to deriving the gravitational field equations. The calculations of the isotropic and homogeneous cosmological models are undertaken in the Jordan frame and at both the background and the perturbation levels. For the former, we also discuss the connection to the Einstein frame in which the extra degree of freedom in the theory is associated with a scalar field sharing some of the properties of a “chameleon” field. For the latter, we derive the cosmological perturbation equations in general theories of f(R) gravity in covariant form and implement them numerically to calculate the cosmic microwave background (CMB) temperature and matter power spectra of the cosmological model. The CMB power is shown to reduce at low l’s, and the matter power spectrum is almost scale independent at small scales, thus having a similar shape to that in standard general relativity. These are in stark contrast with what was found in the Palatini f(R) gravity, where the CMB power is largely amplified at low l’s and the matter spectrum is strongly scale dependent at small scales. These features make the present model more adaptable than that arising from the Palatini f(R) field equations, and none of the data on background evolution, CMB power spectrum, or matter power spectrum currently rule it out.

  20. Spatio-temporal responses of Arabidopsis leaves in photosynthetic performance and metabolite contents to Burkholderia phytofirmans PsJN

    Directory of Open Access Journals (Sweden)

    Fan eSu

    2016-03-01

    Full Text Available A valuable strategy to improve crop yield consists in the use of plant growth-promoting rhizobacteria (PGPRs. However, the influence of PGPR colonization on plant physiology is largely unknown. PGPR Burkholderia phytofirmans strain PsJN (Bp PsJN colonized only Arabidopsis thaliana roots after seed or soil inoculation. Foliar bacteria were detected only after leaf infiltration. Since different bacterial times of presence and/or locations in host plant could lead to different plant physiological responses, photosynthesis and metabolite profiles in A. thaliana leaves were thus investigated following leaf, root or seed inoculation with Bp PsJN. Only Bp PsJN leaf colonization transiently decreased cyclic electron transport and effective quantum yield of photosystem I (PSI, and prevented a decrease in net photosynthesis and stomatal opening compared to the corresponding control. Metabolomic analysis revealed that soluble sugars, amino acids or their derivatives accumulated differently in all Bp PsJN-inoculated plants. Octanoic acid accumulated only in case of inoculated plants. Modifications in vitamin, organic acid such as tricarboxylic acid intermediates, and hormone amounts were dependent on bacterial time of presence and location. Additionally, a larger array of amino acids and hormones (auxin, cytokinin, abscisic acid were modified by seed inoculation with Bp PsJN. Our work thereby provides evidence that relative short-term inoculation with Bp PsJN altered physiological status of A.thaliana leaves, whereas long-term bacterization triggered modifications on a larger set of metabolites. Our data highlighted the changes displayed during this plant-microbe interaction to trigger physiological and metabolic responses that could explain the increase in plant growth or stress tolerance conferred by the presence of Bp PsJN.

  1. Further stable neutron star models from f(R) gravity

    Energy Technology Data Exchange (ETDEWEB)

    Astashenok, Artyom V. [I. Kant Baltic Federal University, Institute of Physics and Technology, Nevskogo st. 14, Kaliningrad, 236041 (Russian Federation); Capozziello, Salvatore [Dipartimento di Fisica, Università di Napoli ' ' Federico II' ' , Via Cinthia, 9, Napoli, I–80126 (Italy); Odintsov, Sergei D., E-mail: artyom.art@gmail.com, E-mail: capozziello@na.infn.it, E-mail: odintsov@ieec.uab.es [Instituciò Catalana de Recerca i Estudis Avançats (ICREA), Barcelona (Spain)

    2013-12-01

    Neutron star models in perturbative f(R) gravity are considered with realistic equations of state. In particular, we consider the FPS, SLy and other equations of state and a case of piecewise equation of state for stars with quark cores. The mass-radius relations for f(R) = R+R(e{sup −R/R{sub 0}}−1) model and for R{sup 2} models with logarithmic and cubic corrections are obtained. In the case of R{sup 2} gravity with cubic corrections, we obtain that at high central densities (ρ > 10ρ{sub ns}, where ρ{sub ns} = 2.7 × 10{sup 14} g/cm{sup 3} is the nuclear saturation density), stable star configurations exist. The minimal radius of such stars is close to 9 km with maximal mass ∼ 1.9M{sub ⊙} (SLy equation). A similar situation takes place for AP4 and BSK20 EoS. Such an effect can give rise to more compact stars than in General Relativity. If observationally identified, such objects could constitute a formidable signature for modified gravity at astrophysical level. Another interesting result can be achieved in modified gravity with only a cubic correction. For some EoS, the upper limit of neutron star mass increases and therefore these EoS can describe realistic star configurations (although, in General Relativity, these EoS are excluded by observational constraints)

  2. Further stable neutron star models from f(R) gravity

    International Nuclear Information System (INIS)

    Astashenok, Artyom V.; Capozziello, Salvatore; Odintsov, Sergei D.

    2013-01-01

    Neutron star models in perturbative f(R) gravity are considered with realistic equations of state. In particular, we consider the FPS, SLy and other equations of state and a case of piecewise equation of state for stars with quark cores. The mass-radius relations for f(R) = R+R(e −R/R 0 −1) model and for R 2 models with logarithmic and cubic corrections are obtained. In the case of R 2 gravity with cubic corrections, we obtain that at high central densities (ρ > 10ρ ns , where ρ ns = 2.7 × 10 14 g/cm 3 is the nuclear saturation density), stable star configurations exist. The minimal radius of such stars is close to 9 km with maximal mass ∼ 1.9M ⊙ (SLy equation). A similar situation takes place for AP4 and BSK20 EoS. Such an effect can give rise to more compact stars than in General Relativity. If observationally identified, such objects could constitute a formidable signature for modified gravity at astrophysical level. Another interesting result can be achieved in modified gravity with only a cubic correction. For some EoS, the upper limit of neutron star mass increases and therefore these EoS can describe realistic star configurations (although, in General Relativity, these EoS are excluded by observational constraints)

  3. 77 FR 16113 - Asiamart, Inc., Order of Suspension of Trading

    Science.gov (United States)

    2012-03-19

    ... SECURITIES AND EXCHANGE COMMISSION [File No. 500-1] Asiamart, Inc., Order of Suspension of Trading... and the protection of investors require a suspension of trading in the securities of the above-listed... trading in the securities of the above-listed company is suspended for the period from 9:30 a.m. EDT on...

  4. 78 FR 44185 - RVPlus, Inc.; Order of Suspension of Trading

    Science.gov (United States)

    2013-07-23

    ... SECURITIES AND EXCHANGE COMMISSION [File No. 500-1] RVPlus, Inc.; Order of Suspension of Trading... and the protection of investors require a suspension of trading in the securities of the above-listed... trading in the securities of the above-listed company is suspended for the period from 9:30 a.m. EDT, on...

  5. Closed string tachyon driving f(R) cosmology

    Science.gov (United States)

    Wang, Peng; Wu, Houwen; Yang, Haitang

    2018-05-01

    To study quantum effects on the bulk tachyon dynamics, we replace R with f(R) in the low-energy effective action that couples gravity, the dilaton, and the bulk closed string tachyon of bosonic closed string theory and study properties of their classical solutions. The α' corrections of the graviton-dilaton-tachyon system are implemented in the f(R). We obtain the tachyon-induced rolling solutions and show that the string metric does not need to remain fixed in some cases. In the case with H( t=‑∞ ) = , only the R and R2 terms in f(R) play a role in obtaining the rolling solutions with nontrivial metric. The singular behavior of more classical solutions are investigated and found to be modified by quantum effects. In particular, there could exist some classical solutions, in which the tachyon field rolls down from a maximum of the tachyon potential while the dilaton expectation value is always bounded from above during the rolling process.

  6. f(R) gravity, torsion and non-metricity

    International Nuclear Information System (INIS)

    Sotiriou, Thomas P

    2009-01-01

    For both f(R) theories of gravity with an independent symmetric connection (no torsion), usually referred to as Palatini f(R) gravity theories, and for f(R) theories of gravity with torsion but no non-metricity, called U4 theories, it has been shown that the independent connection can actually be eliminated algebraically, as long as this connection does not couple to matter. Remarkably, the outcome in both cases is the same theory, which is dynamically equivalent with an ω 0 = -3/2 Brans-Dicke theory. It is shown here that even for the most general case of an independent connection with both non-metricity and torsion, one arrives at exactly the same theory as in the more restricted cases. This generalizes the previous results and explains why assuming that either the torsion or the non-metricity vanishing ultimately leads to the same theory. It also demonstrates that f(R) actions cannot support an independent connection which carries dynamical degrees of freedom, irrespective of how general this connection is, at least as long as there is no connection-matter coupling. (fast track communication)

  7. Standard cosmological evolution in the f(R) model to Kaluza-Klein cosmology

    International Nuclear Information System (INIS)

    Aghmohammadi, A; Abolhassani, M R; Saaidi, Kh; Vajdi, A

    2009-01-01

    In this paper, using f(R) theory of gravity we explicitly calculate cosmological evolution in the presence of a perfect fluid source in four- and five-dimensional space-time in which this cosmological evolution in self-creation is presented by Reddy et al (2009 Int. J. Theor. Phys. 48 10). An exact cosmological model is presented using a relation between Einstein's gravity field equation components due to a metric with the same component from f(R) theory of gravity. Some physics and kinematical properties of the model are also discussed.

  8. Effective Dark Matter Halo Catalog in f(R) Gravity.

    Science.gov (United States)

    He, Jian-Hua; Hawken, Adam J; Li, Baojiu; Guzzo, Luigi

    2015-08-14

    We introduce the idea of an effective dark matter halo catalog in f(R) gravity, which is built using the effective density field. Using a suite of high resolution N-body simulations, we find that the dynamical properties of halos, such as the distribution of density, velocity dispersion, specific angular momentum and spin, in the effective catalog of f(R) gravity closely mimic those in the cold dark matter model with a cosmological constant (ΛCDM). Thus, when using effective halos, an f(R) model can be viewed as a ΛCDM model. This effective catalog therefore provides a convenient way for studying the baryonic physics, the galaxy halo occupation distribution and even semianalytical galaxy formation in f(R) cosmologies.

  9. Constraints on perturbative f(R) gravity via neutron stars

    Energy Technology Data Exchange (ETDEWEB)

    Arapoğlu, Savaş; Ekşi, K. Yavuz [İstanbul Technical University, Faculty of Science and Letters, Physics Engineering Department, Maslak 34469, İstanbul (Turkey); Deliduman, Cemsinan, E-mail: arapoglu@itu.edu.tr, E-mail: cemsinan@msgsu.edu.tr, E-mail: eksi@itu.edu.tr [Mimar Sinan Fine Arts University, Department of Physics, Beşiktaş 34349, İstanbul (Turkey)

    2011-07-01

    We study the structure of neutron stars in perturbative f(R) gravity models with realistic equations of state. We obtain mass-radius relations in a gravity model of the form f(R) = R+αR{sup 2}. We find that deviations from the results of general relativity, comparable to the variations due to using different equations of state (EoS'), are induced for |α| ∼ 10{sup 9} cm{sup 2}. Some of the soft EoS' that are excluded within the framework of general relativity can be reconciled with the 2 solar mass neutron star recently observed for certain values of α within this range. For some of the EoS' we find that a new solution branch, which allows highly massive neutron stars, exists for values of α greater than a few 10{sup 9} cm{sup 2}. We find constraints on α for a variety of EoS' using the recent observational constraints on the mass-radius relation. These are all 5 orders of magnitude smaller than the recent constraint obtained via Gravity Probe B for this gravity model. The associated length scale √(alpha)approx 10{sup 5} cm is only an order of magnitude smaller than the typical radius of a neutron star, the probe used in this test. This implies that real deviations from general relativity can be even smaller.

  10. Wormholes in R{sup 2}-gravity within the f(R, T) formalism

    Energy Technology Data Exchange (ETDEWEB)

    Sahoo, P.K.; Sahoo, Parbati [Birla Institute of Technology and Science-Pilani, Department of Mathematics, Hyderabad (India); Moraes, P.H.R.S. [ITA-Instituto Tecnologico de Aeronautica, Departamento de Fisica, Sao Jose dos Campos, Sao Paulo (Brazil)

    2018-01-15

    We propose, as a novelty in the literature, the modeling of wormholes within a particular case of f(R, T) gravity, namely f(R, T) = R + αR{sup 2} + λT, with R and T being the Ricci scalar and trace of the energy-momentum tensor, respectively, while α and λ are constants. Although such a functional form application can be found in the literature, those concern compact astrophysical objects, such that no wormhole analysis has been done so far. The quadratic geometric and linear material corrections of this theory render the matter content of the wormhole remarkably able to obey the energy conditions. (orig.)

  11. Existence of relativistic stars in f(R) gravity

    International Nuclear Information System (INIS)

    Upadhye, Amol; Hu, Wayne

    2009-01-01

    We refute recent claims in the literature that stars with relativistically deep potentials cannot exist in f(R) gravity. Numerical examples of stable stars, including relativistic (GM * /r * ∼0.1), constant density stars, are studied. As a star is made larger, nonlinear 'chameleon' effects screen much of the star's mass, stabilizing gravity at the stellar center. Furthermore, we show that the onset of this chameleon screening is unrelated to strong gravity. At large central pressures P>ρ/3, f(R) gravity, like general relativity, does have a maximum gravitational potential, but at a slightly smaller value: GM * /r * | max =0.345<4/9 for constant density and one choice of parameters. This difference is associated with negative central curvature R under general relativity not being accessed in the f(R) model, but does not apply to any known astrophysical object.

  12. f(R) gravity: scalar perturbations in the late Universe

    Czech Academy of Sciences Publication Activity Database

    Eingorn, M.; Novák, Jan; Zhuk, A.

    2014-01-01

    Roč. 74, č. 8 (2014), s. 3005 ISSN 1434-6044 Institutional support: RVO:67985840 Keywords : nonlinear f(R) gravity * scalar cosmological perturbations * scalaron Subject RIV: BA - General Mathematics Impact factor: 5.084, year: 2014 http://link.springer.com/article/10.1140/epjc/s10052-014-3005-1

  13. Models of f(R) cosmic acceleration that evade solar system tests

    International Nuclear Information System (INIS)

    Hu, Wayne; Sawicki, Ignacy

    2007-01-01

    We study a class of metric-variation f(R) models that accelerates the expansion without a cosmological constant and satisfies both cosmological and solar-system tests in the small-field limit of the parameter space. Solar-system tests alone place only weak bounds on these models, since the additional scalar degree of freedom is locked to the high-curvature general-relativistic prediction across more than 25 orders of magnitude in density, out through the solar corona. This agreement requires that the galactic halo be of sufficient extent to maintain the galaxy at high curvature in the presence of the low-curvature cosmological background. If the galactic halo and local environment in f(R) models do not have substantially deeper potentials than expected in ΛCDM, then cosmological field amplitudes |f R | > or approx.10 -6 will cause the galactic interior to evolve to low curvature during the acceleration epoch. Viability of large-deviation models therefore rests on the structure and evolution of the galactic halo, requiring cosmological simulations of f(R) models, and not directly on solar-system tests. Even small deviations that conservatively satisfy both galactic and solar-system constraints can still be tested by future, percent-level measurements of the linear power spectrum, while they remain undetectable to cosmological-distance measures. Although we illustrate these effects in a specific class of models, the requirements on f(R) are phrased in a nearly model-independent manner

  14. f(R) gravity cosmology in scalar degree of freedom

    International Nuclear Information System (INIS)

    Goswami, Umananda Dev; Deka, Kabita

    2014-01-01

    The models of f(R) gravity belong to an important class of modified gravity models where the late time cosmic accelerated expansion is considered as the manifestation of the large scale modification of the force of gravity. f(R) gravity models can be expressed in terms of a scalar degree of freedom by explicit redefinition of model's variable. Here we report about the study of the features of cosmological parameters and hence the cosmological evolution using the scalar degree of freedom of the f(R) = ξR n gravity model in the Friedmann-Lemaître-Robertson-Walker (FLRW) background

  15. Constraint propagation equations of the 3+1 decomposition of f(R) gravity

    International Nuclear Information System (INIS)

    Paschalidis, Vasileios; Shapiro, Stuart L; Halataei, Seyyed M H; Sawicki, Ignacy

    2011-01-01

    Theories of gravity other than general relativity (GR) can explain the observed cosmic acceleration without a cosmological constant. One such class of theories of gravity is f(R). Metric f(R) theories have been proven to be equivalent to Brans-Dicke (BD) scalar-tensor gravity without a kinetic term (ω = 0). Using this equivalence and a 3+1 decomposition of the theory, it has been shown that metric f(R) gravity admits a well-posed initial value problem. However, it has not been proven that the 3+1 evolution equations of metric f(R) gravity preserve the (Hamiltonian and momentum) constraints. In this paper, we show that this is indeed the case. In addition, we show that the mathematical form of the constraint propagation equations in BD-equilavent f(R) gravity and in f(R) gravity in both the Jordan and Einstein frames is exactly the same as in the standard ADM 3+1 decomposition of GR. Finally, we point out that current numerical relativity codes can incorporate the 3+1 evolution equations of metric f(R) gravity by modifying the stress-energy tensor and adding an additional scalar field evolution equation. We hope that this work will serve as a starting point for relativists to develop fully dynamical codes for valid f(R) models.

  16. Magnetic suspension of a rotating system. Application to inertial flywheels

    International Nuclear Information System (INIS)

    Lemarquand, Guy

    1984-01-01

    The various possible magnetic suspension configurations compatible with rotating mechanical systems are defined from studies of the characteristics of different types of magnetic bearings. The results obtained are used in the design and realization of a magnetic suspension for an inertial flywheel. (author) [fr

  17. Robust approach to f(R) gravity

    International Nuclear Information System (INIS)

    Jaime, Luisa G.; Patino, Leonardo; Salgado, Marcelo

    2011-01-01

    We consider metric f(R) theories of gravity without mapping them to their scalar-tensor counterpart, but using the Ricci scalar itself as an ''extra'' degree of freedom. This approach avoids then the introduction of a scalar-field potential that might be ill defined (not single valued). In order to explicitly show the usefulness of this method, we focus on static and spherically symmetric spacetimes and deal with the recent controversy about the existence of extended relativistic objects in certain class of f(R) models.

  18. Possible antigravity regions in F(R) theory?

    Energy Technology Data Exchange (ETDEWEB)

    Bamba, Kazuharu, E-mail: bamba@kmi.nagoya-u.ac.jp [Kobayashi-Maskawa Institute for the Origin of Particles and the Universe, Nagoya University, Nagoya 464-8602 (Japan); Nojiri, Shin' ichi, E-mail: nojiri@phys.nagoya-u.ac.jp [Kobayashi-Maskawa Institute for the Origin of Particles and the Universe, Nagoya University, Nagoya 464-8602 (Japan); Department of Physics, Nagoya University, Nagoya 464-8602 (Japan); Odintsov, Sergei D., E-mail: odintsov@ieec.uab.es [Department of Physics, Nagoya University, Nagoya 464-8602 (Japan); Instituciò Catalana de Recerca i Estudis Avançats (ICREA), Barcelona (Spain); Institut de Ciencies de l' Espai (CSIC-IEEC), Campus UAB, Facultat de Ciencies, Torre C5-Par-2a pl, E-08193 Bellaterra (Barcelona) (Spain); Tomsk State Pedagogical University, Kievskaya Avenue, 60, 634061, Tomsk (Russian Federation); Sáez-Gómez, Diego, E-mail: diego.saezgomez@uct.ac.za [Astrophysics, Cosmology and Gravity Centre (ACGC) and Department of Mathematics and Applied Mathematics, University of Cape Town, Rondebosch 7701, Cape Town (South Africa); Fisika Teorikoaren eta Zientziaren Historia Saila, Zientzia eta Teknologia Fakultatea, Euskal Herriko Unibertsitatea, 644 Posta Kutxatila, 48080 Bilbao (Spain)

    2014-03-07

    We construct an F(R) gravity theory corresponding to the Weyl invariant two scalar field theory. We investigate whether such F(R) gravity can have the antigravity regions where the Weyl curvature invariant does not diverge at the Big Bang and Big Crunch singularities. It is revealed that the divergence cannot be evaded completely but can be much milder than that in the original Weyl invariant two scalar field theory.

  19. Holographic dark energy and f(R) gravity

    Energy Technology Data Exchange (ETDEWEB)

    Aghamohammadi, A [Faculty of Science, Islamic Azad University of Sanandaj, Sanandaj (Iran, Islamic Republic of); Saaidi, Kh, E-mail: ksaaidi@uok.ac.ir, E-mail: agha35484@yahoo.com [Department of Physics, Faculty of Science, University of Kurdistan, Sanandaj (Iran, Islamic Republic of)

    2011-02-15

    We investigate the corresponding relation between f(R) gravity and holographic dark energy. We introduce a type of energy density from f(R) that has the same role as holographic dark energy. We obtain the differential equation that specifies the evolution of the introduced energy density parameter based on a varying gravitational constant. We discover the relation for the equation of state parameter for low redshifts that contains varying G correction.

  20. Possible antigravity regions in F(R) theory?

    Science.gov (United States)

    Bamba, Kazuharu; Nojiri, Shin'ichi; Odintsov, Sergei D.; Sáez-Gómez, Diego

    2014-03-01

    We construct an F(R) gravity theory corresponding to the Weyl invariant two scalar field theory. We investigate whether such F(R) gravity can have the antigravity regions where the Weyl curvature invariant does not diverge at the Big Bang and Big Crunch singularities. It is revealed that the divergence cannot be evaded completely but can be much milder than that in the original Weyl invariant two scalar field theory.

  1. Possible antigravity regions in F(R) theory?

    International Nuclear Information System (INIS)

    Bamba, Kazuharu; Nojiri, Shin'ichi; Odintsov, Sergei D.; Sáez-Gómez, Diego

    2014-01-01

    We construct an F(R) gravity theory corresponding to the Weyl invariant two scalar field theory. We investigate whether such F(R) gravity can have the antigravity regions where the Weyl curvature invariant does not diverge at the Big Bang and Big Crunch singularities. It is revealed that the divergence cannot be evaded completely but can be much milder than that in the original Weyl invariant two scalar field theory.

  2. f(R) constant-roll inflation

    Energy Technology Data Exchange (ETDEWEB)

    Motohashi, Hayato [Universidad de Valencia-CSIC, Instituto de Fisica Corpuscular (IFIC), Valencia (Spain); Starobinsky, Alexei A. [L.D. Landau Institute for Theoretical Physics, RAS, Moscow (Russian Federation); National Research University Higher School of Economics, Moscow (Russian Federation)

    2017-08-15

    The previously introduced class of two-parametric phenomenological inflationary models in general relativity in which the slow-roll assumption is replaced by the more general, constant-roll condition is generalized to the case of f(R) gravity. A simple constant-roll condition is defined in the original Jordan frame, and exact expressions for a scalaron potential in the Einstein frame, for a function f(R) (in the parametric form) and for inflationary dynamics are obtained. The region of the model parameters permitted by the latest observational constraints on the scalar spectral index and the tensor-to-scalar ratio of primordial metric perturbations generated during inflation is determined. (orig.)

  3. 77 FR 1656 - Proposed Establishment of Restricted Areas R-5402, R-5403A, R-5403B, R-5403C, R-5403D, R-5403E, R...

    Science.gov (United States)

    2012-01-11

    ...-0117; Airspace Docket No. 09-AGL-31] RIN 2120-AI92 Proposed Establishment of Restricted Areas R-5402, R-5403A, R- 5403B, R-5403C, R-5403D, R-5403E, R-5403F; Devils Lake, ND AGENCY: Federal Aviation... Restricted Areas R-5402, R-5403A, R-5403B, R- 5403C, R-5403D, R-5403E, R-5403F; Devils Lake, ND (76 FR 72869...

  4. Stellar configurations in f(R) theories of gravity

    International Nuclear Information System (INIS)

    Henttunen, K.; Multamaeki, T.; Vilja, I.

    2008-01-01

    We study stellar configurations and the space-time around them in metric f(R) theories of gravity. In particular, we focus on the polytropic model of the Sun in two specific cases: the f(R)=R-μ 4 /R model and a model with a stabilizing higher order term f(R)=R-μ 4 /R+βR 3 /(3μ 4 ). We show how the stellar configuration in the f(R) theory can, by appropriate initial conditions, be selected to be equal to that described by the Lane-Emden equation and how a simple scaling relation exists between the solutions. We also derive the correct solution analytically near the center of the star in f(R) theory. Previous analytical and numerical results are confirmed, indicating that the space-time around the Sun is incompatible with solar system constraints in the f(R)=R-μ 4 /R model. Numerical work shows that stellar configurations, with a regular metric at the center, lead to γ PPN ≅1/2 outside the star for both models, i.e., the Schwarzschild-de Sitter space-time is not the correct vacuum solution for such configurations. This shows that even when one fine-tunes the initial conditions inside a star such that the mass of the effective scalar in the equivalent scalar-tensor theory is large, γ PPN is still 1/2 outside the star. Conversely, by selecting the Schwarzschild-de Sitter metric as the outside solution, or equivalently setting the mass of the effective scalar to be large outside the star, we find that the stellar configuration is unchanged but the metric is irregular at the center. The possibility of constructing a f(R) theory compatible with the solar system experiments and possible new constraints arising from the radius-mass relation of stellar objects is discussed

  5. Cosmological reconstruction of realistic modified F(R) gravities

    International Nuclear Information System (INIS)

    Nojiri, Shin'ichi; Odintsov, Sergei D.; Saez-Gomez, Diego

    2009-01-01

    The cosmological reconstruction scheme for modified F(R) gravity is developed in terms of e-folding (or, redshift). It is demonstrated how any FRW cosmology may emerge from specific F(R) theory. The specific examples of well-known cosmological evolution are reconstructed, including ΛCDM cosmology, deceleration with transition to phantom superacceleration era which may develop singularity or be transient. The application of this scheme to viable F(R) gravities unifying inflation with dark energy era is proposed. The additional reconstruction of such models leads to non-leading gravitational correction mainly relevant at the early/late universe and helping to pass the cosmological bounds (if necessary). It is also shown how cosmological reconstruction scheme may be generalized in the presence of scalar field.

  6. 78 FR 33142 - Lanbo Financial Group, Inc.; Order of Suspension of Trading

    Science.gov (United States)

    2013-06-03

    ... Suspension of Trading May 30, 2013. It appears to the Securities and Exchange Commission that there is a lack... the opinion that the public interest and the protection of investors require a suspension of trading... the Securities Exchange Act of 1934, that trading in the securities of the above-listed company is...

  7. A simple route to prepare stable hydroxyapatite nanoparticles suspension

    International Nuclear Information System (INIS)

    Han Yingchao; Wang Xinyu; Li Shipu

    2009-01-01

    A simple ultrasound assisted precipitation method with addition of glycosaminoglycans (GAGs) is proposed to prepare stable hydroxyapatite (HAP) nanoparticles suspension from the mixture of Ca(H 2 PO 4 ) 2 solution and Ca(OH) 2 solution. The product was characterized by XRD, FT-IR, TEM, HRTEM and particle size, and zeta potential analyzer. TEM observation shows that the suspension is composed of 10-20 nm x 20-50 nm short rod-like and 10-30 nm similar spherical HAP nanoparticles. The number-averaged particle size of stable suspension is about 30 nm between 11.6 and 110.5 nm and the zeta potential is -60.9 mV. The increase of stability of HAP nanoparticles suspension mainly depends on the electrostatic effect and steric effect of GAGs. The HAP nanoparticles can be easily transported into the cancer cells and exhibit good potential as gene or drug carrier system.

  8. Cosmology of Horava-Lifshitz f(R) gravity

    International Nuclear Information System (INIS)

    Chakrabarti, Sayan K.; Sen, Anjan A.

    2011-08-01

    We discuss the cosmology of recently proposed Horava-Lifshitz f(R) gravity. In particular, we derive the modified Hubble equation that reduces to the standard HL gravity case in appropriate limit. We show how the bounce solutions in this theory are modified due to nonlinear effect of f(R) gravity. In addition we find that the solutions exist when the Universe can make turn around for large scale-factor. Therefore, in principle, the Universe in this set-up can show cyclic behavior. (orig.)

  9. Cosmology of Horava-Lifshitz f(R) gravity

    Energy Technology Data Exchange (ETDEWEB)

    Chakrabarti, Sayan K. [Univ. Tecnica de Lisboa (Portugal). Inst. Superior Tecnico; Dutta, Koushik [Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany); Sen, Anjan A. [Centre of Theoretical Physics, Jamia Millia Islamia, New Dehli (India)

    2011-08-15

    We discuss the cosmology of recently proposed Horava-Lifshitz f(R) gravity. In particular, we derive the modified Hubble equation that reduces to the standard HL gravity case in appropriate limit. We show how the bounce solutions in this theory are modified due to nonlinear effect of f(R) gravity. In addition we find that the solutions exist when the Universe can make turn around for large scale-factor. Therefore, in principle, the Universe in this set-up can show cyclic behavior. (orig.)

  10. Burkholderia phytofirmans PsJN reduces damages to freezing temperature in Arabidopsis thaliana

    Directory of Open Access Journals (Sweden)

    Fan eSU

    2015-10-01

    Full Text Available Several plant growth-promoting rhizobacteria (PGPR are known to improve plant tolerance to multiple stresses, including low temperatures. However, mechanisms underlying this protection are still poorly understood. The aim of this study was to evaluate the role of the endophytic PGPR, Burkholderia phytofirmans strain PsJN (Bp PsJN, on Arabidopsis thaliana cold tolerance using photosynthesis parameters as physiological markers.Under standard conditions, our results indicated that Bp PsJN inoculation led to growth promotion of Arabidopsis plants without significant modification on photosynthesis parameters and chloroplast organization. However, bacterial colonization induced a cell wall strengthening in the mesophyllImpact of inoculation modes (either on seeds or by soil irrigation and their effects overnight at 0, -1 or -3°C, were investigated by following photosystem II (PSII activity and gas exchanges. Following low temperatures stress, a decrease of photosynthesis parameters was observed. In addition, during three consecutive nights or days at -1°C, PSII activity was monitored. Pigment contents, RuBisCO protein abundance, expression of several genes including RbcS, RbcL, CBF1, CBF2, CBF3, ICE1, COR15a, and COR78 were evaluated at the end of exposure. To assess the impact of the bacteria on cell ultrastructure under low temperatures, microscopic observations were achieved. Results indicated that freezing treatment induced significant changes in PSII activity as early as the first cold day, whereas the same impact on PSII activity was observed only during the third cold night. The significant effects conferred by PsJN were differential accumulation of pigments, and reduced expression of RbcL and COR78. Microscopical observations showed an alteration/disorganization in A. thaliana leaf mesophyll cells independently of the freezing treatments. The presence of bacteria during the three successive nights or days did not significantly improved A

  11. 17 CFR 201.520 - Suspension of registration of brokers, dealers, or other Exchange Act-registered entities...

    Science.gov (United States)

    2010-04-01

    ... brokers, dealers, or other Exchange Act-registered entities: Application. 201.520 Section 201.520... Rules Relating to Temporary Orders and Suspensions § 201.520 Suspension of registration of brokers... of a registered broker, dealer, municipal securities dealer, government securities broker, government...

  12. 17 CFR 201.540 - Appeal and Commission review of initial decision making a temporary order permanent.

    Science.gov (United States)

    2010-04-01

    ... 17 Commodity and Securities Exchanges 2 2010-04-01 2010-04-01 false Appeal and Commission review of initial decision making a temporary order permanent. 201.540 Section 201.540 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION RULES OF PRACTICE Rules of Practice Rules Relating to Temporary Orders and Suspensions § 201.540...

  13. 75 FR 38943 - Airworthiness Directives; McDonnell Douglas Corporation Model DC-10-10, DC-10-10F, DC-10-30, DC...

    Science.gov (United States)

    2010-07-07

    ...-0672; Directorate Identifier 2010-NM-047-AD] RIN 2120-AA64 Airworthiness Directives; McDonnell Douglas...: McDonnell Douglas Corporation: Docket No. FAA-2010-0672; Directorate Identifier 2010-NM-047-AD. Comments Due... applies to McDonnell Douglas Corporation Model DC- 10-10, DC-10-10F, DC-10-30, DC-10-30F (KDC-10), DC-10...

  14. 76 FR 63355 - Proposed Information Collection (Regulation on Application for Fisher Houses and Other Temporary...

    Science.gov (United States)

    2011-10-12

    ... (Regulation on Application for Fisher Houses and Other Temporary Lodging and VHA Fisher House Application... information technology. Title: Regulation on Application for Fisher Houses and Other Temporary Lodging and VHA Fisher House Application, VA Forms 10-0408 and 10-0408a. OMB Control Number: 2900-0630. Type of Review...

  15. 75 FR 63040 - Airworthiness Directives; McDonnell Douglas Corporation Model DC-10-10, DC-10-10F, DC-10-30, DC...

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    2010-10-14

    ... Airworthiness Directives; McDonnell Douglas Corporation Model DC- 10-10, DC-10-10F, DC-10-30, DC-10-30F (KDC-10... following new airworthiness directive (AD): 2010-21-13 McDonnell Douglas Corporation: Amendment 39-16473... November 18, 2010. Affected ADs (b) None. Applicability (c) This AD applies to McDonnell Douglas...

  16. Late-time cosmological approach in mimetic f(R, T) gravity

    Energy Technology Data Exchange (ETDEWEB)

    Baffou, E.H. [Institut de Mathematiques et de Sciences Physiques (IMSP), Porto-Novo (Benin); Houndjo, M.J.S. [Institut de Mathematiques et de Sciences Physiques (IMSP), Porto-Novo (Benin); Faculte des Sciences et Techniques de Natitingou, Natitingou (Benin); Hamani-Daouda, M. [Universite de Niamey, Departement de Physique, Niamey (Niger); Alvarenga, F.G. [Universidade Federal do Espirito Santo, Departamento de Engenharia e Ciencias Naturais, CEUNES, Sao Mateus, ES (Brazil)

    2017-10-15

    In this paper, we investigate the late-time cosmic acceleration in mimetic f(R, T) gravity with the Lagrange multiplier and potential in a Universe containing, besides radiation and dark energy, a self-interacting (collisional) matter. We obtain through the modified Friedmann equations the main equation that can describe the cosmological evolution. Then, with several models from Q(z) and the well-known particular model f(R, T), we perform an analysis of the late-time evolution. We examine the behavior of the Hubble parameter, the dark energy equation of state and the total effective equation of state and in each case we compare the resulting picture with the non-collisional matter (assumed as dust) and also with the collisional matter in mimetic f(R, T) gravity. The results obtained are in good agreement with the observational data and show that in the presence of the collisional matter the dark energy oscillations in mimetic f(R, T) gravity can be damped. (orig.)

  17. Generation of spherically symmetric metrics in f(R) gravity

    Energy Technology Data Exchange (ETDEWEB)

    Amirabi, Z.; Halilsoy, M.; Mazharimousavi, S.H. [Eastern Mediterranean University, Department of Physics, Gazimagusa (Turkey)

    2016-06-15

    In D-dimensional spherically symmetric f(R) gravity there are three unknown functions to be determined from the fourth order differential equations. It is shown that the system remarkably may be integrated to relate two functions through the third one to provide a reduction to second order equations accompanied with a large class of potential solutions. The third function, which acts as the generator of the process, is F(R) = (df(R))/(dR). We recall that our generating function has been employed as a scalar field with an accompanying self-interacting potential previously, which is entirely different from our approach. Reduction of f(R) theory into a system of equations seems to be efficient enough to generate a solution corresponding to each generating function. As particular examples, besides the known ones, we obtain new black hole solutions in any dimension D. We further extend our analysis to cover non-zero energy-momentum tensors. Global monopole and Maxwell sources are given as examples. (orig.)

  18. Rational approximations of f(R) cosmography through Pad'e polynomials

    Science.gov (United States)

    Capozziello, Salvatore; D'Agostino, Rocco; Luongo, Orlando

    2018-05-01

    We consider high-redshift f(R) cosmography adopting the technique of polynomial reconstruction. In lieu of considering Taylor treatments, which turn out to be non-predictive as soon as z>1, we take into account the Pad&apose rational approximations which consist in performing expansions converging at high redshift domains. Particularly, our strategy is to reconstruct f(z) functions first, assuming the Ricci scalar to be invertible with respect to the redshift z. Having the so-obtained f(z) functions, we invert them and we easily obtain the corresponding f(R) terms. We minimize error propagation, assuming no errors upon redshift data. The treatment we follow naturally leads to evaluating curvature pressure, density and equation of state, characterizing the universe evolution at redshift much higher than standard cosmographic approaches. We therefore match these outcomes with small redshift constraints got by framing the f(R) cosmology through Taylor series around 0zsimeq . This gives rise to a calibration procedure with small redshift that enables the definitions of polynomial approximations up to zsimeq 10. Last but not least, we show discrepancies with the standard cosmological model which go towards an extension of the ΛCDM paradigm, indicating an effective dark energy term evolving in time. We finally describe the evolution of our effective dark energy term by means of basic techniques of data mining.

  19. F(R Gravity’s Rainbow and Its Einstein Counterpart

    Directory of Open Access Journals (Sweden)

    S. H. Hendi

    2016-01-01

    Full Text Available Motivated by UV completion of general relativity with a modification of a geometry at high energy scale, it is expected to have an energy dependent geometry. In this paper, we introduce charged black hole solutions with power Maxwell invariant source in the context of gravity’s rainbow. In addition, we investigate two classes of F(R gravity’s rainbow solutions. At first, we study energy dependent F(R gravity without energy-momentum tensor, and then we obtain F(R gravity’s rainbow in the presence of conformally invariant Maxwell source. We study geometrical properties of the mentioned solutions and compare their results. We also give some related comments regarding thermodynamical behavior of the obtained solutions and discuss thermal stability of the solutions.

  20. Exploring the liminality: properties of haloes and subhaloes in borderline f(R) gravity

    Science.gov (United States)

    Shi, Difu; Li, Baojiu; Han, Jiaxin; Gao, Liang; Hellwing, Wojciech A.

    2015-09-01

    We investigate the properties of dark matter haloes and subhaloes in an f(R) gravity model with |fR0| = 10-6, using a very-high-resolution N-body simulation. The model is a borderline between being cosmologically interesting and yet still consistent with current data. We find that the halo mass function in this model has a maximum 20 per cent enhancement compared with the Λ-cold-dark-matter (ΛCDM) predictions between z = 1 and 0. Because of the chameleon mechanism which screens the deviation from standard gravity in dense environments, haloes more massive than 1013 h-1 M⊙ in this f(R) model have very similar properties to haloes of similar mass in ΛCDM, while less massive haloes, such as that of the Milky Way, can have steeper inner density profiles and higher velocity dispersions due to their weaker screening. The halo concentration is remarkably enhanced for low-mass haloes in this model due to a deepening of the total gravitational potential. Contrary to the naive expectation, the halo formation time zf is later for low-mass haloes in this model, a consequence of these haloes growing faster than their counterparts in ΛCDM at late times and the definition of zf. Subhaloes, especially those less massive than 1011 h-1 M⊙, are substantially more abundant in this f(R) model for host haloes less massive than 1013 h-1 M⊙. We discuss the implications of these results for the Milky Way satellite abundance problem. Although the overall halo and subhalo properties in this borderline f(R) model are close to their ΛCDM predictions, our results suggest that studies of the Local Group and astrophysical systems, aided by high-resolution simulations, can be valuable for further tests of it.

  1. 42 CFR 488.415 - Temporary management.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 5 2010-10-01 2010-10-01 false Temporary management. 488.415 Section 488.415... Compliance for Long-Term Care Facilities with Deficiencies § 488.415 Temporary management. (a) Definition. Temporary management means the temporary appointment by CMS or the State of a substitute facility manager or...

  2. The holographic bound in the scalar-tensor and f(R) gravities

    International Nuclear Information System (INIS)

    Firouzjaee, J.T.

    2013-01-01

    The holographic bound has been extended to the different theory of gravities such as scalar-tensor gravity and f(R) gravity according to the Noether charge definition of the entropy for a black hole surface. We have introduced some popular examples of the flat FRW cosmology in order to investigate holographic bound in scalar-tensor and f(R) gravity. Using the holographic bound, we put an additional constraint on scalar-tensor gravity and the f(R) gravity parameters. We also discuss the transformation from Jordan frame to Einstein frame. (orig.)

  3. 76 FR 36287 - Temporary Exemptions and Other Temporary Relief, Together With Information on Compliance Dates...

    Science.gov (United States)

    2011-06-22

    ... Econ. Dep't, Bank for Int'l Settlements, Triennial and Semiannual Surveys--Positions in Global Over-the...-Based Swap Data Repository Registration, Duties, and Core Principles, 75 FR 77305 (Dec. 10, 2010..., duties, and core principles for SB SEFs. See Registration and Regulation of Security-Based Swap Execution...

  4. Le developpement de Limacella glioderma (Fr.) R. Maire

    NARCIS (Netherlands)

    Reijnders, A.F.M.

    1979-01-01

    A comparison of the development of Limacella guttata (Fr.) Konrad & Maublanc with that of L. glioderma (Fr.) R. Maire shows clearly that the latter is of a more primitive type. This conclusion is based on the following observations: a. Limacella guttata has a pileocarpic development: the first

  5. Propagating Degrees of Freedom in f(R Gravity

    Directory of Open Access Journals (Sweden)

    Yun Soo Myung

    2016-01-01

    Full Text Available We have computed the number of polarization modes of gravitational waves propagating in the Minkowski background in f(R gravity. These are three of two from transverse-traceless tensor modes and one from a massive trace mode, which confirms the results found in the literature. There is no massless breathing mode and the massive trace mode corresponds to the Ricci scalar. A newly defined metric tensor in f(R gravity satisfies the transverse-traceless (TT condition as well as the TT wave equation.

  6. The coincidence problem in holographic f(R) gravity

    Energy Technology Data Exchange (ETDEWEB)

    Bisabr, Yousef, E-mail: y-bisabr@srttu.edu [Department of Physics, Shahid Rajaee Teacher Training University, Lavizan, Tehran 16788 (Iran, Islamic Republic of)

    2011-09-15

    It is well known that f(R) gravity models formulated in the Einstein conformal frame are equivalent to Einstein gravity together with a minimally coupled scalar field. In this case, the scalar field couples with the matter sector and the coupling term is given by the conformal factor. We apply the holographic principle to such interacting models. In a spatially flat universe, we show that the Einstein frame representation of f(R) models leads to a constant ratio of energy densities of dark matter to dark energy.

  7. Distinguishing f(R) theories from general relativity by gravitational lensing effect

    Energy Technology Data Exchange (ETDEWEB)

    Liu, Hongguang [Beijing Normal University, Department of Physics, Beijing (China); Aix Marseille Universite et Universite de Toulon, Centre de Physique Theorique (UMR 7332), Marseille (France); Wang, Xin; Li, Haida; Ma, Yongge [Beijing Normal University, Department of Physics, Beijing (China)

    2017-11-15

    The post-Newtonian formulation of a general class of f(R) theories is set up in a third-order approximation. It turns out that the information of a specific form of f(R) gravity is encoded in the Yukawa potential, which is contained in the perturbative expansion of the metric components. Although the Yukawa potential is canceled in the second-order expression of the effective refraction index of light, detailed analysis shows that the difference of the lensing effect between the f(R) gravity and general relativity does appear at the third order when √(f''(0)/f{sup '}(0)) is larger than the distance d{sub 0} to the gravitational source. However, the difference between these two kinds of theories will disappear in the axially symmetric spacetime region. Therefore only in very rare case the f(R) theories are distinguishable from general relativity by gravitational lensing effect in a third-order post-Newtonian approximation. (orig.)

  8. General proof of the entropy principle for self-gravitating fluid in f(R) gravity

    Energy Technology Data Exchange (ETDEWEB)

    Fang, Xiongjun [Department of Physics and Key Laboratory of Low Dimensional Quantum Structures andQuantum Control of Ministry of Education, Hunan Normal University,Changsha, Hunan 410081 (China); Guo, Minyong [Department of Physics, Beijing Normal University,Beijing 100875 (China); Jing, Jiliang [Department of Physics and Key Laboratory of Low Dimensional Quantum Structures andQuantum Control of Ministry of Education, Hunan Normal University,Changsha, Hunan 410081 (China)

    2016-08-29

    The discussions on the connection between gravity and thermodynamics attract much attention recently. We consider a static self-gravitating perfect fluid system in f(R) gravity, which is an important theory could explain the accelerated expansion of the universe. We first show that the Tolman-Oppenheimer-Volkoff equation of f(R) theories can be obtained by thermodynamical method in spherical symmetric spacetime. Then we prove that the maximum entropy principle is also valid for f(R) gravity in general static spacetimes beyond spherical symmetry. The result shows that if the constraint equation is satisfied and the temperature of fluid obeys Tolmans law, the extrema of total entropy implies other components of gravitational equations. Conversely, if f(R) gravitational equation hold, the total entropy of the fluid should be extremum. Our work suggests a general and solid connection between f(R) gravity and thermodynamics.

  9. 41 CFR 301-10.124 - What are coach-class Seating Upgrade Programs?

    Science.gov (United States)

    2010-07-01

    ... traveler's personal choice and therefore is at the traveler's personal expense. An agency travel... Travel Regulation System TEMPORARY DUTY (TDY) TRAVEL ALLOWANCES ALLOWABLE TRAVEL EXPENSES 10... reimburse the additional seat choice fee, according to internal agency policy. [FTR Amdt. 2009-06, 74 FR...

  10. Thermodynamic laws for generalized f(R) gravity with curvature-matter coupling

    International Nuclear Information System (INIS)

    Wu Yabo; Zhao Yueyue; Cai Ronggen; Lu Jianbo; Lu Junwang; Gao Xiaojing

    2012-01-01

    The first law and the generalized second law (GSL) of thermodynamics for the generalized f(R) gravity with curvature-matter coupling are studied in the spatially homogeneous, isotropic FRW universe. The research results show that the field equations of the generalized f(R) gravity with curvature-matter coupling can be cast to the form of the first law of thermodynamics with the so-called the entropy production terms dS ¯ and the GSL can be given by considering the FRW universe filled only with ordinary matter enclosed by the dynamical apparent horizon with the Hawking temperature. Furthermore, as a concrete example, by utilizing the GSL the constraints on the gravitational model with f 1 (R)=R+αR l and f 2 (R)=R m are also discussed. It is worth noting these results given by us are quite general and can degenerate to the ones in Einstein's general relativity and pure f(R) gravity with non-coupling and non-minimal coupling as special cases. Comparing with the case of Einstein's general relativity, the appearance of the entropy production term dS ¯ in the first law of thermodynamics demonstrates that the horizon thermodynamics is non-equilibrium one for generalized f(R) gravity with curvature-matter coupling, which is consistent with the arguments given in Akbar and Cai (2007) [13] and Eling et al. (2006) [18].

  11. Constraining f(R gravity in solar system, cosmology and binary pulsar systems

    Directory of Open Access Journals (Sweden)

    Tan Liu

    2018-02-01

    Full Text Available The f(R gravity can be cast into the form of a scalar–tensor theory, and scalar degree of freedom can be suppressed in high-density regions by the chameleon mechanism. In this article, for the general f(R gravity, using a scalar–tensor representation with the chameleon mechanism, we calculate the parametrized post-Newtonian parameters γ and β, the effective gravitational constant Geff, and the effective cosmological constant Λeff. In addition, for the general f(R gravity, we also calculate the rate of orbital period decay of the binary system due to gravitational radiation. Then we apply these results to specific f(R models (Hu–Sawicki model, Tsujikawa model and Starobinsky model and derive the constraints on the model parameters by combining the observations in solar system, cosmological scales and the binary systems.

  12. A no-hair theorem for black holes in f(R) gravity

    Science.gov (United States)

    Cañate, Pedro

    2018-01-01

    In this work we present a no-hair theorem which discards the existence of four-dimensional asymptotically flat, static and spherically symmetric or stationary axisymmetric, non-trivial black holes in the frame of f(R) gravity under metric formalism. Here we show that our no-hair theorem also can discard asymptotic de Sitter stationary and axisymmetric non-trivial black holes. The novelty is that this no-hair theorem is built without resorting to known mapping between f(R) gravity and scalar–tensor theory. Thus, an advantage will be that our no-hair theorem applies as well to metric f(R) models that cannot be mapped to scalar–tensor theory.

  13. Extension of loop quantum gravity to f(R) theories.

    Science.gov (United States)

    Zhang, Xiangdong; Ma, Yongge

    2011-04-29

    The four-dimensional metric f(R) theories of gravity are cast into connection-dynamical formalism with real su(2) connections as configuration variables. Through this formalism, the classical metric f(R) theories are quantized by extending the loop quantization scheme of general relativity. Our results imply that the nonperturbative quantization procedure of loop quantum gravity is valid not only for general relativity but also for a rather general class of four-dimensional metric theories of gravity.

  14. 77 FR 15650 - Fisher House and Other Temporary Lodging

    Science.gov (United States)

    2012-03-16

    ... DEPARTMENT OF VETERANS AFFAIRS 38 CFR Part 60 RIN 2900-AN79 Fisher House and Other Temporary... Affairs (VA) proposes to amend its regulations concerning Fisher House and other temporary lodging... assistance and clarify the distinctions between Fisher House and other temporary lodging provided by VA. The...

  15. 30 CFR 816.131 - Cessation of operations: Temporary.

    Science.gov (United States)

    2010-07-01

    ..., revegetation, environmental monitoring, and water treatment activities that will continue during the temporary... Section 816.131 Mineral Resources OFFICE OF SURFACE MINING RECLAMATION AND ENFORCEMENT, DEPARTMENT OF THE INTERIOR PERMANENT PROGRAM PERFORMANCE STANDARDS PERMANENT PROGRAM PERFORMANCE STANDARDS-SURFACE MINING...

  16. Constraint on reconstructed f(R) gravity models from gravitational waves

    Science.gov (United States)

    Lee, Seokcheon

    2018-06-01

    The gravitational wave (GW) detection of a binary neutron star inspiral made by the Advanced LIGO and Advanced Virgo paves the unprecedented way for multi-messenger observations. The propagation speed of this GW can be scrutinized by comparing the arrival times between GW and neutrinos or photons. It provides the constraint on the mass of the graviton. f(R) gravity theories have the habitual non-zero mass gravitons in addition to usual massless ones. Previously, we show that the model independent f(R) gravity theories can be constructed from the both background evolution and the matter growth with one undetermined parameter. We show that this parameter can be constrained from the graviton mass bound obtained from GW detection. Thus, the GW detection provides the invaluable constraint on the validity of f(R) gravity theories.

  17. Cosmic constraint on massive neutrinos in viable f(R) gravity with producing ΛCDM background expansion

    Energy Technology Data Exchange (ETDEWEB)

    Lu, Jianbo; Wu, Yabo; Wang, Yan; Yang, Weiqiang [Liaoning Normal University, Department of Physics, Dalian (China); Liu, Molin [Xinyang Normal University, Department of Physics, Xinyang (China)

    2016-12-15

    Tensions between several cosmic observations were found recently, such as the inconsistent values of H{sub 0} (or σ{sub 8}) were indicated by the different cosmic observations. Introducing the massive neutrinos in ΛCDM could potentially solve the tensions. Viable f(R) gravity producing ΛCDM background expansion with massive neutrinos is investigated in this paper. We fit the current observational data: Planck-2015 CMB, RSD, BAO, and SNIa to constrain the mass of neutrinos in viable f(R) theory. The constraint results at 95% confidence level are: Σm{sub ν} < 0.202 eV for the active-neutrino case, m{sub ν,sterile}{sup eff} < 0.757 eV with N{sub eff} < 3.22 for the sterile neutrino case. For the effects due to the mass of the neutrinos, the constraint results on model parameter at 95% confidence level become f{sub R0} x 10{sup -6} > -1.89 and f{sub R0} x 10{sup -6} > -2.02 for two cases, respectively. It is also shown that the fitting values of several parameters much depend on the neutrino properties, such as the cold dark matter density, the cosmological quantities at matter-radiation equality, the neutrino density and the fraction of baryonic mass in helium. Finally, the constraint result shows that the tension between direct and CMB measurements of H{sub 0} gets slightly weaker in the viable f(R) model than that in the base ΛCDM model. (orig.)

  18. Pitched Blade Turbine Efficiency at Particle Suspension

    Directory of Open Access Journals (Sweden)

    D. Ceres

    2010-01-01

    Full Text Available Mixing suspensions is a very important hydraulic operation. The pitched six-blade turbine is a widely-used axial-flow impeller. This paper deals with effect relative impeller size and particle content on theefficiency of a pitched six-blade turbine at particle suspension. Two pitched six-blade turbines were used in model measurements of just suspension impeller speed. The ratios of the vessel to agitator diameter D/d were 3 and 4.5. The measurements were carried out in a dish-bottomed vessel 300 mm in diameter. The just suspension impeller speeds were measured using an electrochemical method, and were checked visually. A 2.5 % NaCl water solution was used as the liquid phase, and glass particles with four equivalent diameters between 0.18 and 0.89 mmand volumetric concentration from 2.5 % to 40% were usedasthesolid phase. The criterion values πs=Po√Fr'3(d/D7 were calculated from the particle suspension and power consumption measurements. The dependencies of πs on particle content cv show that larger agitators are more efficient for higher particle content.

  19. Probing the f(R) formalism through gravitational wave polarizations

    International Nuclear Information System (INIS)

    Alves, M.E.S.; Miranda, O.D.; Araujo, J.C.N. de

    2009-01-01

    The direct observation of gravitational waves (GW) in the near future, and the corresponding determination of the number of independent polarizations, is a powerful tool to test general relativity and alternative theories of gravity. In the present work we use the Newman-Penrose formalism to characterize GWs in quadratic gravity and in a particular class of f(R) Lagrangians. We find that both quadratic gravity and the f(R) theory belong to the most general invariant class of GWs, i.e., they can present up to six independent polarizations of GWs. For a particular combination of the parameters, we find that quadratic gravity can present up to five polarizations states. On the other hand, if we use the Palatini approach for f(R) theories, GWs present only the usual two transverse-traceless polarizations such as in general relativity. Thus, we conclude that the observation of GWs can strongly constrain the suitable formalism for these theories.

  20. On Analytical Solutions of f(R) Modified Gravity Theories in FLRW Cosmologies

    Science.gov (United States)

    Domazet, Silvije; Radovanović, Voja; Simonović, Marko; Štefančić, Hrvoje

    2013-02-01

    A novel analytical method for f(R) modified theories without matter in Friedmann-Lemaitre-Robertson-Walker (FLRW) spacetimes is introduced. The equation of motion for the scale factor in terms of cosmic time is reduced to the equation for the evolution of the Ricci scalar R with the Hubble parameter H. The solution of equation of motion for actions of the form of power law in Ricci scalar R is presented with a detailed elaboration of the action quadratic in R. The reverse use of the introduced method is exemplified in finding functional forms f(R), which leads to specified scale factor functions. The analytical solutions are corroborated by numerical calculations with excellent agreement. Possible further applications to the phases of inflationary expansion and late-time acceleration as well as f(R) theories with radiation are outlined.

  1. f(R in Holographic and Agegraphic Dark Energy Models and the Generalized Uncertainty Principle

    Directory of Open Access Journals (Sweden)

    Barun Majumder

    2013-01-01

    Full Text Available We studied a unified approach with the holographic, new agegraphic, and f(R dark energy model to construct the form of f(R which in general is responsible for the curvature driven explanation of the very early inflation along with presently observed late time acceleration. We considered the generalized uncertainty principle in our approach which incorporated the corrections in the entropy-area relation and thereby modified the energy densities for the cosmological dark energy models considered. We found that holographic and new agegraphic f(R gravity models can behave like phantom or quintessence models in the spatially flat FRW universe. We also found a distinct term in the form of f(R which goes as R 3 / 2 due to the consideration of the GUP modified energy densities. Although the presence of this term in the action can be important in explaining the early inflationary scenario, Capozziello et al. recently showed that f(R ~ R 3 / 2 leads to an accelerated expansion, that is, a negative value for the deceleration parameter q which fits well with SNeIa and WMAP data.

  2. Reconstructing an f(R) model from holographic dark energy: using the observational evidence

    International Nuclear Information System (INIS)

    Saaidi, Kh; Aghamohammadi, A

    2012-01-01

    We investigate the correspondence relation between f(R) gravity and an interacting holographic dark energy (HDE). By obtaining the conditions needed for some observational evidence such as positive acceleration expansion of the Universe, crossing the phantom divide line and validity of the thermodynamics second law in an interacting HDE model and corresponding it with the f(R) model of gravity, we find a viable f(R) model that can explain the present Universe. We also obtain the explicit evolutionary forms of the corresponding scalar field, potential and scale factor of the Universe. (paper)

  3. String duality transformations in f(R) gravity from Noether symmetry approach

    Energy Technology Data Exchange (ETDEWEB)

    Capozziello, Salvatore [Dipartimento di Fisica, Università di Napoli ' ' Federico II' ' , Compl. Univ. di Monte S. Angelo, Edificio G, Via Cinthia, I-80126, Napoli (Italy); Gionti, Gabriele S.J. [Specola Vaticana, Vatican City, V-00120, Vatican City State (Vatican City State, Holy See); Vernieri, Daniele, E-mail: capozziello@na.inf.it, E-mail: ggionti@as.arizona.edu, E-mail: vernieri@iap.fr [Sorbonne Universités, UPMC Univ Paris 6 et CNRS, UMR 7095, Institut d' Astrophysique de Paris, GReCO, 98bis Bd Arago, 75014 Paris (France)

    2016-01-01

    We select f(R) gravity models that undergo scale factor duality transformations. As a starting point, we consider the tree-level effective gravitational action of bosonic String Theory coupled with the dilaton field. This theory inherits the Busher's duality of its parent String Theory. Using conformal transformations of the metric tensor, it is possible to map the tree-level dilaton-graviton string effective action into f(R) gravity, relating the dilaton field to the Ricci scalar curvature. Furthermore, the duality can be framed under the standard of Noether symmetries and exact cosmological solutions are derived. Using suitable changes of variables, the string-based f(R) Lagrangians are shown in cases where the duality transformation becomes a parity inversion.

  4. String duality transformations in f(R) gravity from Noether symmetry approach

    International Nuclear Information System (INIS)

    Capozziello, Salvatore; Gionti, Gabriele S.J.; Vernieri, Daniele

    2016-01-01

    We select f(R) gravity models that undergo scale factor duality transformations. As a starting point, we consider the tree-level effective gravitational action of bosonic String Theory coupled with the dilaton field. This theory inherits the Busher's duality of its parent String Theory. Using conformal transformations of the metric tensor, it is possible to map the tree-level dilaton-graviton string effective action into f(R) gravity, relating the dilaton field to the Ricci scalar curvature. Furthermore, the duality can be framed under the standard of Noether symmetries and exact cosmological solutions are derived. Using suitable changes of variables, the string-based f(R) Lagrangians are shown in cases where the duality transformation becomes a parity inversion

  5. Unifying inflation with dark energy in modified F(R) Horava-Lifshitz gravity

    International Nuclear Information System (INIS)

    Elizalde, E.; Saez-Gomez, D.; Nojiri, S.; Odintsov, S.D.

    2010-01-01

    We study FRW cosmology for a non-linear modified F(R) Horava-Lifshitz gravity which has a viable convenient counterpart. A unified description of early-time inflation and late-time acceleration is possible in this theory, but the cosmological dynamic details are generically different from the ones of the convenient viable F(R) model. Remarkably, for some specific choice of parameters they do coincide. The emergence of finite-time future singularities is investigated in detail. It is shown that these singularities can be cured by adding an extra, higher-derivative term, which turns out to be qualitatively different when compared with the corresponding one of the convenient F(R) theory. (orig.)

  6. Late time acceleration of the universe in f(R) gravity model

    International Nuclear Information System (INIS)

    Mukherjee, Ankan

    2014-01-01

    In this work, a new way to look at the nature of late time dynamics of the universe for f(R) gravity models using the contracted Bianchi Identity has been proposed. As the Einstein field equations contain derivatives of the curvature scalar R, the contracted Bianchi identity yields a second order nonlinear differential equation in H, the Hubble parameter. This equation is studied for two particular forms of f(R), and the late time behaviour of the model is discussed. (author)

  7. 17 CFR 269.10 - Form TH-Notification of reliance on temporary hardship exemption.

    Science.gov (United States)

    2010-04-01

    ... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Form TH-Notification of....10 Form TH—Notification of reliance on temporary hardship exemption. Form TH shall be filed by any...: For Federal Register citations affecting Form TH, see the List of CFR Sections Affected, which appears...

  8. Nedestruktivní hodnocení a monitorování ocelových a betonových stavebních konstrukcí

    Czech Academy of Sciences Publication Activity Database

    Převorovský, Zdeněk; Kober, Jan; Krofta, Josef; Chlada, Milan

    2013-01-01

    Roč. 23, 1-2 (2013), s. 24-29 ISSN 1213-3825 R&D Projects: GA MPO(CZ) FR-TI1/198 Institutional support: RVO:61388998 Keywords : structural health monitoring * civil structures * nonlinear elastic wave spectroscopy * acoustic emission Subject RIV: JN - Civil Engineering

  9. Pair-correlations in swimmer suspensions

    Science.gov (United States)

    Nambiar, Sankalp; Subramanian, Ganesh

    2017-11-01

    Suspensions of rear-actuated swimming microorganisms, such as E.coli, exhibit several interesting phenomena including spontaneous pattern formation above a critical concentration, novel rheological properties, shear-induced concentration banding etc. Explanations based on mean-field theory are only qualitative, since interactions between swimmers are important for typical experimental concentrations. We analytically characterize the hydrodynamic pair-interactions in a quiescent suspension of slender straight swimmers. The pair-correlation, calculated at leading order by integrating the swimmer velocity disturbances along straight trajectories, decays as 1/r2 for r >> L (L being the swimmer size). This allows us to characterize both polar and nematic correlations in an interacting swimmer suspension. In the absence of correlations, the velocity covariance asymptotes from a constant for r > L, the latter being characteristic of a suspension of non-interacting point force-dipoles. On including correlations, the slow decay of the pair-orientation correlation leads to an additional contribution to the velocity covariance that diverges logarithmically with system size.

  10. Stability of the Einstein static universe in f(R, T) gravity

    Energy Technology Data Exchange (ETDEWEB)

    Shabani, Hamid [University of Sistan and Baluchestan, Physics Department, Faculty of Sciences, Zahedan (Iran, Islamic Republic of); Ziaie, Amir Hadi [Kahnooj Branch, Islamic Azad University, Department of Physics, Kerman (Iran, Islamic Republic of)

    2017-01-15

    The Einstein static (ES) universe has played a major role in various emergent scenarios recently proposed in order to cure the problem of the initial singularity of the standard model of cosmology. In the model we address, we study the existence and stability of an ES universe in the context of f(R, T) modified theories of gravity. Considering specific forms of the f(R, T) function, we seek for the existence of solutions representing ES state. Using dynamical system techniques along with numerical analysis, we find two classes of solutions: the first one is always unstable of the saddle type, while the second is always stable so that its dynamical behavior corresponds to a center equilibrium point. The importance of the second class of solutions is due to the significant role they play in constructing non-singular emergent models in which the universe could have experienced past-eternally a series of infinite oscillations about such an initial static state after which it enters, through a suitable physical mechanism, to an inflationary era. Considering specific forms for the functionality of f(R, T), we show that this theory is capable of providing cosmological solutions which admit emergent universe (EU) scenarios. We also investigate homogeneous scalar perturbations for the mentioned models. The stability regions of the solutions are parametrized by a linear equation of state (EoS) parameter and other free parameters that will be introduced for the models. Our results suggest that modifications in f(R, T) gravity would lead to stable solutions which are unstable in f(R) gravity model. (orig.)

  11. Stability of the Einstein static universe in f(R, T) gravity

    International Nuclear Information System (INIS)

    Shabani, Hamid; Ziaie, Amir Hadi

    2017-01-01

    The Einstein static (ES) universe has played a major role in various emergent scenarios recently proposed in order to cure the problem of the initial singularity of the standard model of cosmology. In the model we address, we study the existence and stability of an ES universe in the context of f(R, T) modified theories of gravity. Considering specific forms of the f(R, T) function, we seek for the existence of solutions representing ES state. Using dynamical system techniques along with numerical analysis, we find two classes of solutions: the first one is always unstable of the saddle type, while the second is always stable so that its dynamical behavior corresponds to a center equilibrium point. The importance of the second class of solutions is due to the significant role they play in constructing non-singular emergent models in which the universe could have experienced past-eternally a series of infinite oscillations about such an initial static state after which it enters, through a suitable physical mechanism, to an inflationary era. Considering specific forms for the functionality of f(R, T), we show that this theory is capable of providing cosmological solutions which admit emergent universe (EU) scenarios. We also investigate homogeneous scalar perturbations for the mentioned models. The stability regions of the solutions are parametrized by a linear equation of state (EoS) parameter and other free parameters that will be introduced for the models. Our results suggest that modifications in f(R, T) gravity would lead to stable solutions which are unstable in f(R) gravity model. (orig.)

  12. Intensive neutron source based on powerful electron linear accelerator LIA-30 and pulsed nuclear reactor FR-1

    Energy Technology Data Exchange (ETDEWEB)

    Bossamykin, V S; Koshelev, A S; Gerasimov, A I; Gordeev, V S; Grishin, A V; Averchenkov, V Ya; Lazarev, S A; Maslov, G N; Odintsov, Yu M [All-Russian Scientific Research Institute of Experimental Physics, Sarov (Russian Federation)

    1997-12-31

    Some results are given of investigations on joint operation modes of the linear induction electron accelerator LIA-30 ({approx} 40 MeV, {approx} 100 kA, {approx} 20 ns) and the pulsed reactor FR-1 with a compact metal core, aimed at achieving high intensity neutron fluxes. The multiplication factor Q for prompt neutrons in the FR-1 booster mode operation increased from 100 to 4500. The total output of prompt neutrons from FR-1 at Q = 2570 was 1.4 x 10{sup 16} 1/pulse with a pulse half width of {approx} 25 {mu}s. (author). 4 figs., 4 refs.

  13. 77 FR 71825 - Notice of Temporary Restriction of Vehicle Use and Temporary Closure to Tree Cutting and Wood...

    Science.gov (United States)

    2012-12-04

    ... to Tree Cutting and Wood Harvesting on Public Land in Douglas County, NV AGENCY: Bureau of Land... a temporary closure to wood harvesting and/or tree cutting on public land within the Topaz Ranch... temporary restriction of cross-country vehicle travel and a temporary closure to tree cutting and wood...

  14. Transient transfection of serum-free suspension HEK 293 cell culture for efficient production of human rFVIII

    Science.gov (United States)

    2011-01-01

    Background Hemophilia A is a bleeding disorder caused by deficiency in coagulation factor VIII. Recombinant factor VIII (rFVIII) is an alternative to plasma-derived FVIII for the treatment of hemophilia A. However, commercial manufacturing of rFVIII products is inefficient and costly and is associated to high prices and product shortage, even in economically privileged countries. This situation may be solved by adopting more efficient production methods. Here, we evaluated the potential of transient transfection in producing rFVIII in serum-free suspension HEK 293 cell cultures and investigated the effects of different DNA concentration (0.4, 0.6 and 0.8 μg/106 cells) and repeated transfections done at 34° and 37°C. Results We observed a decrease in cell growth when high DNA concentrations were used, but no significant differences in transfection efficiency and in the biological activity of the rFVIII were noticed. The best condition for rFVIII production was obtained with repeated transfections at 34°C using 0.4 μg DNA/106 cells through which almost 50 IU of active rFVIII was produced six days post-transfection. Conclusion Serum-free suspension transient transfection is thus a viable option for high-yield-rFVIII production. Work is in progress to further optimize the process and validate its scalability. PMID:22115125

  15. Exact solutions for scalar field cosmology in f(R) gravity

    Science.gov (United States)

    Maharaj, S. D.; Goswami, R.; Chervon, S. V.; Nikolaev, A. V.

    2017-09-01

    We study scalar field FLRW cosmology in the content of f(R) gravity. Our consideration is restricted to the spatially flat Friedmann universe. We derived the general evolution equations of the model, and showed that the scalar field equation is automatically satisfied for any form of the f(R) function. We also derived representations for kinetic and potential energies, as well as for the acceleration in terms of the Hubble parameter and the form of the f(R) function. Next we found the exact cosmological solutions in modified gravity without specifying the f(R) function. With negligible acceleration of the scalar curvature, we found that the de Sitter inflationary solution is always attained. Also we obtained new solutions with special restrictions on the integration constants. These solutions contain oscillating, accelerating, decelerating and even contracting universes. For further investigation, we selected special cases which can be applied with early or late inflation. We also found exact solutions for the general case for the model with negligible acceleration of the scalar curvature in terms of special Airy functions. Using initial conditions which represent the universe at the present epoch, we determined the constants of integration. This allows for the comparison of the scale factor in the new solutions with that for current stage of the universe evolution in the ΛCDM model.

  16. Utilization of recombinant Trichoderma reesei expressing Aspergillus aculeatus β-glucosidase I (JN11) for a more economical production of ethanol from lignocellulosic biomass.

    Science.gov (United States)

    Treebupachatsakul, Treesukon; Shioya, Koki; Nakazawa, Hikaru; Kawaguchi, Takashi; Morikawa, Yasushi; Shida, Yosuke; Ogasawara, Wataru; Okada, Hirofumi

    2015-12-01

    The capacity of Trichoderma reesei cellulase to degrade lignocellulosic biomass has been enhanced by the construction of a recombinant T. reesei strain expressing Aspergillus aculeatus β-glucosidase I. We have confirmed highly efficient ethanol production from converge-milled Japanese cedar by recombinant T. reesei expressing A. aculeatus β-glucosidase I (JN11). We investigated the ethanol productivity of JN11 and compared it with the cocktail enzyme T. reesei PC-3-7 with reinforced cellobiase activity by the commercial Novozyme 188. Results showed that the ethanol production efficiency under enzymatic hydrolysis of JN11 was comparable to the cocktail enzyme both on simultaneous saccharification and fermentation (SSF) or separate hydrolysis and fermentation (SHF) processes. Moreover, the cocktail enzyme required more protein loading for attaining similar levels of ethanol conversion as JN11. We propose that JN11 is an intrinsically economical enzyme that can eliminate the supplementation of BGL for PC-3-7, thereby reducing the cost of industrial ethanol production from lignocellulosic biomass. Copyright © 2015 The Society for Biotechnology, Japan. Published by Elsevier B.V. All rights reserved.

  17. Chameleon halo modeling in f(R) gravity

    International Nuclear Information System (INIS)

    Li Yin; Hu, Wayne

    2011-01-01

    We model the chameleon effect on cosmological statistics for the modified gravity f(R) model of cosmic acceleration. The chameleon effect, required to make the model compatible with local tests of gravity, reduces force enhancement as a function of the depth of the gravitational potential wells of collapsed structure and so is readily incorporated into a halo model by including parameters for the chameleon mass threshold and rapidity of transition. We show that the abundance of halos around the chameleon mass threshold is enhanced by both the merging from below and the lack of merging to larger masses. This property also controls the power spectrum in the nonlinear regime and we provide a description of the transition to the linear regime that is valid for a wide range of f(R) models.

  18. 75 FR 66653 - Airworthiness Directives; McDonnell Douglas Corporation Model MD-90-30 Airplanes

    Science.gov (United States)

    2010-10-29

    ... Airworthiness Directives; McDonnell Douglas Corporation Model MD- 90-30 Airplanes AGENCY: Federal Aviation...-15667 (73 FR 52203, September 9, 2008), and adding the following new AD: 2010-22-04 McDonnell Douglas... supersedes AD 2008-18-10, Amendment 39-15667. Applicability (c) This AD applies to McDonnell Douglas...

  19. Thick brane in f(R) gravity with Palatini dynamics

    Energy Technology Data Exchange (ETDEWEB)

    Bazeia, D.; Losano, L. [Universidade Federal da Paraiba, Departamento de Fisica, Joao Pessoa, PB (Brazil); Menezes, R. [Universidade Federal da Paraiba, Departamento de Ciencias Exatas, Rio Tinto, PB (Brazil); Universidade Federal de Campina Grande, Departamento de Fisica, Campina Grande, PB (Brazil); Olmo, Gonzalo J. [Universidade Federal da Paraiba, Departamento de Fisica, Joao Pessoa, PB (Brazil); Universidad de Valencia, Departamento de Fisica Teorica, IFIC, Centro Mixto Universidad de Valencia-CSIC, Burjassot, Valencia (Spain); Rubiera-Garcia, D. [Universidade Federal da Paraiba, Departamento de Fisica, Joao Pessoa, PB (Brazil); Universidade de Lisboa, Faculdade de Ciencias, Instituto de Astrofisica e Ciencias do Espaco, Lisbon (Portugal); Fudan University, Department of Physics, Center for Field Theory and Particle Physics, Shanghai (China)

    2015-12-15

    This work deals with modified gravity in five-dimensional space-time. We study a thick Palatini f(R) brane, that is, a braneworld scenario described by an anti-de Sitter warped geometry with a single extra dimension of infinite extent, sourced by a real scalar field under the Palatini approach, where the metric and the connection are regarded as independent degrees of freedom. We consider a first-order framework which we use to provide exact solutions for the scalar field and warp factor. We also investigate a perturbative scenario such that the Palatini approach is implemented through a Lagrangian f(R) = R + εR{sup n}, where the small parameter ε controls the deviation from the standard thick brane case. In both cases it is found that the warp factor tends to localize the extra dimension due to the nonlinear corrections. (orig.)

  20. Torsional asymmetry in suspension bridge systems

    Czech Academy of Sciences Publication Activity Database

    Malík, Josef

    2015-01-01

    Roč. 60, č. 6 (2015), s. 677-701 ISSN 0862-7940 R&D Projects: GA MŠk ED2.1.00/03.0082 Institutional support: RVO:68145535 Keywords : suspension bridge * Hamilton principle * vertical and torsional oscillation * uniqueness * existence Subject RIV: BA - General Mathematics Impact factor: 0.507, year: 2015 http://link.springer.com/article/10.1007%2Fs10492-015-0117-3

  1. rändrat omhändertagande av patienter med uretärsten : - Lärdomar från ett förbättringsarbete

    OpenAIRE

    Khatami, Annelie

    2014-01-01

    Bakgrund: Omkring 10-15 % av befolkningen, oftast i arbetsför ålder, riskerar att någon gång drabbas av njursten. Nationella riktlinjer för njurstensbehandling saknas, men studier stödjer behandling inom 48 timmar för snabb symtomlindring och minskade besvärr patienten. Inom studerad verksamhet var tiden från diagnos till behandling lång och återinläggningarna var många, varför ett förbättringsarbete initierades. Syfte: Syftet med förbättringsarbetet var att halvera tiden från diagnos till...

  2. Boundary Effects and Shear Thickening of Colloidal Suspensions: A study based on measurement of Suspension Microstructure

    Science.gov (United States)

    Perera, M. Tharanga D.

    Microstructure is key to understanding rheological behaviors of flowing particulate suspensions. During the past decade, Stokesian Dynamics simulations have been the dominant method of determining suspension microstructure. Structure results obtained numerically reveal that an anisotropic structure is formed under high Peclet (Pe) number conditions. Researchers have used various experimental techniques such as small angle neutron scattering (SANS) and light scattering methods to validate microstructure. This work outlines an experimental technique based on confocal microscopy to study microstructure of a colloidal suspension in an index-matched fluid flowing in a microchannel. High resolution scans determining individual particle locations in suspensions 30-50 vol % yield quantitative results of the local microstructure in the form of the pair distribution function, g(r). From these experimentally determined g(r), the effect of shear rate, quantified by the Peclet number as a ratio of shear and Brownian stress, on the suspension viscosity and normal stress follow that seen in macroscopic rheological measurements and simulations. It is generally believed that shear thickening behavior of colloidal suspensions is driven by the formation of hydroclusters. From measurements of particle locations, hydroclusters are identified. The number of hydroclusters grows exponentially with increasing Pe, and the onset of shear thickening is driven by the increase in formation of clusters having 5-8 particles. At higher Pe, we notice the emergence of 12 or more particle clusters. The internal structure of these hydroclusters has been investigated, and there is some evidence that particles internal to hydroclusters preferentially align along the 45° and 135° axis. Beyond observations of bulk suspension behavior, the influence of boundaries on suspension microstructure is also investigated. Experiments were performed for suspensions flowing over smooth walls, made of glass

  3. Generalisation for regular black holes on general relativity to f(R) gravity

    Energy Technology Data Exchange (ETDEWEB)

    Rodrigues, Manuel E. [Universidade Federal do Para Campus Universitario de Abaetetuba, Faculdade de Ciencias Exatas e Tecnologia, Abaetetuba, Para (Brazil); Universidade Federal do Para, Faculdade de Fisica, PPGF, Belem, Para (Brazil); Fabris, Julio C. [Universidade Federal do Espirito Santo, Vitoria, ES (Brazil); National Research Nuclear University MEPhI, Moscow (Russian Federation); Junior, Ednaldo L.B. [Universidade Federal do Para, Faculdade de Fisica, PPGF, Belem, Para (Brazil); Universidade Federal do Para, Campus Universitario de Tucurui, Faculdade de Engenharia da Computacao, Tucurui, Para (Brazil); Marques, Glauber T. [Universidade Federal Rural da Amazonia ICIBE - LASIC, Belem, PA (Brazil)

    2016-05-15

    IIn this paper, we determine regular black hole solutions using a very general f(R) theory, coupled to a nonlinear electromagnetic field given by a Lagrangian L{sub NED}. The functions f(R) and L{sub NED} are in principle left unspecified. Instead, the model is constructed through a choice of the mass function M(r) presented in the metric coefficients. Solutions which have a regular behaviour of the geometric invariants are found. These solutions have two horizons, the event horizon and the Cauchy horizon. All energy conditions are satisfied in the whole space-time, except the strong energy condition (SEC), which is violated near the Cauchy horizon.We present also a new theorem related to the energy conditions in f(R) gravity, re-obtaining the well-known conditions in the context of general relativity when the geometry of the solution is the same. (orig.)

  4. Static spherically symmetric wormholes in f(R, T) gravity

    Energy Technology Data Exchange (ETDEWEB)

    Zubair, M.; Ahmad, Yasir [Institute Of Information Technology, Department of Mathematics, COMSATS, Lahore (Pakistan); Waheed, Saira [Prince Mohammad Bin Fahd University, Al Khobar (Saudi Arabia)

    2016-08-15

    In this work, we explore wormhole solutions in f(R, T) theory of gravity, where R is the scalar curvature and T is the trace of stress-energy tensor of matter. To investigate this, we consider a static spherically symmetric geometry with matter contents as anisotropic, isotropic, and barotropic fluids in three separate cases. By taking into account the Starobinsky f(R) model, we analyze the behavior of energy conditions for these different kinds of fluids. It is shown that the wormhole solutions can be constructed without exotic matter in few regions of space-time. We also give the graphical illustration of the results obtained and discuss the equilibrium picture for the anisotropic case only. It is concluded that the wormhole solutions with anisotropic matter are realistic and stable in this theory of gravity. (orig.)

  5. 76 FR 18812 - Submission for Review: RI 30-10, Disabled Dependent Questionnaire

    Science.gov (United States)

    2011-04-05

    ... OFFICE OF PERSONNEL MANAGEMENT Submission for Review: RI 30-10, Disabled Dependent Questionnaire... Dependent Questionnaire. As required by the Paperwork Reduction Act of 1995 (Pub. L. 104-13, 44 U.S.C... (202) 606-0910. SUPPLEMENTARY INFORMATION: The RI 30-10, Disabled Dependent Questionnaire, is used to...

  6. 76 FR 36582 - Submission for Review: Disabled Dependent Questionnaire, RI 30-10

    Science.gov (United States)

    2011-06-22

    ... OFFICE OF PERSONNEL MANAGEMENT Submission for Review: Disabled Dependent Questionnaire, RI 30-10... Dependent Questionnaire. As required by the Paperwork Reduction Act of 1995 (Pub. L. 104-13, 44 U.S.C.... SUPPLEMENTARY INFORMATION: RI 30-10, Disabled Dependent Questionnaire, is used to collect sufficient information...

  7. Power-law cosmic expansion in f(R) gravity models

    International Nuclear Information System (INIS)

    Goheer, Naureen; Larena, Julien; Dunsby, Peter K. S.

    2009-01-01

    We show that within the class of f(R) gravity theories, Friedmann-Lemaitre-Robertson-Walker power-law perfect fluid solutions only exist for R n gravity. This significantly restricts the set of exact cosmological solutions which have similar properties to what is found in standard general relativity.

  8. Administrative license suspension: Does length of suspension matter?

    Science.gov (United States)

    Fell, James C; Scherer, Michael

    2017-08-18

    Administrative license revocation (ALR) laws, which provide that the license of a driver with a blood alcohol concentration at or over the illegal limit is subject to an immediate suspension by the state department of motor vehicles, are an example of a traffic law in which the sanction rapidly follows the offense. The power of ALR laws has been attributed to how swiftly the sanction is applied, but does the length of suspension matter? Our objectives were to (a) determine the relationship of the ALR suspension length to the prevalence of drinking drivers relative to sober drivers in fatal crashes and (b) estimate the extent to which the relationship is associated to the general deterrent effect compared to the specific deterrent effect of the law. Data comparing the impact of ALR law implementation and ALR law suspension periods were analyzed using structural equation modeling techniques on the ratio of drinking drivers to nondrinking drivers in fatal crashes from the Fatality Analysis Reporting System (FARS). States with an ALR law with a short suspension period (1-30 days) had a significantly lower drinking driver ratio than states with no ALR law. States with a suspension period of 91-180 days had significantly lower ratios than states with shorter suspension periods, while the three states with suspension lengths of 181 days or longer had significantly lower ratios than states with shorter suspension periods. The implementation of any ALR law was associated with a 13.1% decrease in the drinking/nondrinking driver fatal crash ratio but only a 1.8% decrease in the intoxicated/nonintoxicated fatal crash ratio. The ALR laws and suspension lengths had a significant general deterrent effect, but no specific deterrent effect. States might want to keep (or adopt) ALR laws for their general deterrent effects and pursue alternatives for specific deterrent effects. States with short ALR suspension periods should consider lengthening them to 91 days or longer.

  9. Mimicking a New 2-Phenylethanol Production Pathway from Proteus mirabilis JN458 in Escherichia coli.

    Science.gov (United States)

    Liu, Jinbin; Jiang, Jing; Bai, Yajun; Fan, Tai-Ping; Zhao, Ye; Zheng, Xiaohui; Cai, Yujie

    2018-04-04

    Bacteria rarely produce natural 2-phenylethanol. We verified a new pathway from Proteus mirabilis JN458 to produce 2-phenylethanol using Escherichia coli to coexpress l-amino acid deaminase, α-keto acid decarboxylase, and alcohol dehydrogenase from P. mirabilis. Based on this pathway, a glucose dehydrogenase coenzyme regeneration system was constructed. The optimal conditions of biotransformation by the recombinant strain E-pAEAKaG were at 40 °C and pH 7.0. Finally, the recombinant strain E-pAEAKaG produced 3.21 ± 0.10 g/L 2-phenylethanol in M9 medium containing 10 g/L l-phenylalanine after a 16 h transformation. Furthermore, when the concentration of l-phenylalanine was 4 g/L (24 mM), the production of 2-phenylethanol reached 2.88 ± 0.18 g/L and displayed a higher conversion rate of 97.38 mol %.

  10. Cystoscopic temporary ureteral catheterization during radical vaginal and abdominal trachelectomy.

    Science.gov (United States)

    Abu-Rustum, Nadeem R; Sonoda, Yukio; Black, Destin; Chi, Dennis S; Barakat, Richard R

    2006-11-01

    approximately 15-20 min. Twenty-eight patients (74%) had 5Fr whistle-tip ureteral catheters inserted, and 10 had open-ended catheters inserted. There were no intraoperative complications. Median hospital stay was 3 days (range, 3-7). Hematuria, evident in the drainage bag attached to the Foley catheter, usually resolved in 24-48 h. Two (20%) of 10 patients who had open-ended catheters inserted developed a transient rise in postoperative creatinine (1.7 and 3.5 mg/dl, respectively) compared to 0/28 patients who had whistle-tip catheters placed (P<0.001). Both were attributed to postoperative distal ureteral edema, and only one patient required reinsertion of temporary ureteral stents. No patient developed long-term urinary complications or fistulae. Cystourethroscopy and bilateral retrograde ureteral catheterization by gynecologic oncologists is a simple and quick procedure that may facilitate identifying the distal ureter during radical vaginal or abdominal trachelectomy. We favor using 5Fr whistle-tip catheters as they may be associated with less ureteral mucosal trauma and subsequent postoperative edema. The skills needed for this procedure should be available to fellows in gynecologic oncology training.

  11. The simplest non-minimal matter-geometry coupling in the f(R, T) cosmology

    Energy Technology Data Exchange (ETDEWEB)

    Moraes, P.H.R.S. [ITA - Instituto Tecnologico de Aeronautica, Departamento de Fisica, Sao Paulo (Brazil); Sahoo, P.K. [Birla Institute of Technology and Science-Pilani, Department of Mathematics, Hyderabad (India)

    2017-07-15

    f(R, T) gravity is an extended theory of gravity in which the gravitational action contains general terms of both the Ricci scalar R and the trace of the energy-momentum tensor T. In this way, f(R, T) models are capable of describing a non-minimal coupling between geometry (through terms in R) and matter (through terms in T). In this article we construct a cosmological model from the simplest non-minimal matter-geometry coupling within the f(R, T) gravity formalism, by means of an effective energy-momentum tensor, given by the sum of the usual matter energy-momentum tensor with a dark energy contribution, with the latter coming from the matter-geometry coupling terms. We apply the energy conditions to our solutions in order to obtain a range of values for the free parameters of the model which yield a healthy and well-behaved scenario. For some values of the free parameters which are submissive to the energy conditions application, it is possible to predict a transition from a decelerated period of the expansion of the universe to a period of acceleration (dark energy era). We also propose further applications of this particular case of the f(R, T) formalism in order to check its reliability in other fields, rather than cosmology. (orig.)

  12. The simplest non-minimal matter-geometry coupling in the f(R, T) cosmology

    International Nuclear Information System (INIS)

    Moraes, P.H.R.S.; Sahoo, P.K.

    2017-01-01

    f(R, T) gravity is an extended theory of gravity in which the gravitational action contains general terms of both the Ricci scalar R and the trace of the energy-momentum tensor T. In this way, f(R, T) models are capable of describing a non-minimal coupling between geometry (through terms in R) and matter (through terms in T). In this article we construct a cosmological model from the simplest non-minimal matter-geometry coupling within the f(R, T) gravity formalism, by means of an effective energy-momentum tensor, given by the sum of the usual matter energy-momentum tensor with a dark energy contribution, with the latter coming from the matter-geometry coupling terms. We apply the energy conditions to our solutions in order to obtain a range of values for the free parameters of the model which yield a healthy and well-behaved scenario. For some values of the free parameters which are submissive to the energy conditions application, it is possible to predict a transition from a decelerated period of the expansion of the universe to a period of acceleration (dark energy era). We also propose further applications of this particular case of the f(R, T) formalism in order to check its reliability in other fields, rather than cosmology. (orig.)

  13. 76 FR 37147 - Notice of Temporary Closures and Temporary Restrictions on Specific Uses of Public Lands in...

    Science.gov (United States)

    2011-06-24

    ... days a week, to leave a message or question with the above individual. You will receive a reply during... provide additional law enforcement officers to work at the event. These temporary closures and temporary... authorized officer. 4. Definitions: (a) Weapon means a firearm, compressed gas or spring powered pistol or...

  14. INDIVIDUAL EMPLOYMENT CONTRACT SUSPENSION IN CASE OF ACTIVITY INTERRUPTION AND / OR THE TEMPORARY ACTIVITY REDUCTION

    Directory of Open Access Journals (Sweden)

    Olimpia-Monica Matiaş

    2012-11-01

    Full Text Available The economic and financial reasons determined by the current crisis have imposed to the Romanian legislator that, in the flexible regulatory context concerning the labour reports, has to intervene to reduce the loss. The legal framework available to the employer in this situation refers to the provisions of the art. 52, 1st paragraph, letter c, art.52, 3rd paragraph, art.53 and 122, 3rd paragraph, all from Law no.40/20111, for Law no.53/2003 modification and amendment concerning the Labour code. Under conditions of economic crisis, it is natural that employers have the necessary means to efficiently organize their activity, meanwhile keeping its staff on these periods. This does not mean that, during the suspension period the employees can not resign, no need to terminate the suspension provided for in Article 52 line 3 of the Labour Code in order to intervene in the individual labor contract termination. From the employer’s perspective there is no ban imposed to him by art. 60 of the Labour Code in relation to this type of suspension, so that the latter may proceed to dismiss the employee during the unilateral suspension of his labor contract arranged under Article 52 line 3 of the Labour Code.

  15. Graphite suspension in carbon dioxide

    International Nuclear Information System (INIS)

    Roche, R.

    1965-01-01

    Since 1963 the Atomic Division of SNECMA has been conducting, under a contract with the CEA, an experimental work with a two-component fluid comprised of carbon dioxide and small graphite particles. The primary purpose was the determination of basic engineering information pertaining to the stability and the flowability of the suspension. The final form of the experimental loop consists mainly of the following items: a light-phase compressor, a heavy-phase pump, an electrical-resistance type heater section, a cooling heat exchanger, a hairpin loop, a transparent test section and a separator. During the course of the testing, it was observed that the fluid could be circulated quite easily in a broad range of variation of the suspension density and velocity - density from 30 to 170 kg/m 3 and velocity from 2 to 24 m/s. The system could be restarted and circulation maintained without any difficulty, even with the heavy-phase pump alone. The graphite did not have a tendency to pack or agglomerate during operation. No graphite deposition was observed on the wall of the tubing. A long period run (250 hours) has shown the evolution of the particle dimensions. Starting with graphite of surface area around 20 m 2 /g (graphite particles about 1 μ), the powder surface area reaches an asymptotic value of 300 m 2 /g (all the particles less than 0.3 μ). Moisture effect on flow stability, flow distribution between two parallel channels, pressure drop in straight tubes, recompression ratio in diffusers were also investigated. (author) [fr

  16. 77 FR 26056 - LocatePlus Holdings Corporation; Order of Suspension of Trading

    Science.gov (United States)

    2012-05-02

    ... Suspension of Trading April 30, 2012. It appears to the Securities and Exchange Commission that there is a... trading in the securities of the above-listed company, and any equity securities of any entity purporting..., that trading in the securities of the above-listed company, and any equity securities of any entity...

  17. Reduction of TIP30 in esophageal squamous cell carcinoma cells involves promoter methylation and microRNA-10b

    Energy Technology Data Exchange (ETDEWEB)

    Dong, Wenjie, E-mail: dongwenjie200581@126.com [Department of Internal Medicine-Oncology, The First Affiliated Hospital, Zhengzhou University (China); Shen, Ruizhe; Cheng, Shidan [Department of Gastroenterology, Rui-jin Hospital, Shanghai Jiao Tong University, Shanghai (China)

    2014-10-31

    Highlights: • TIP30 expression is frequently suppressed in ESCC. • TIP30 was hypermethylated in ESCC. • Reduction of TIP30 was significantly correlated with LN metastasis. • miR-10b is a direct regulator of TIP30. - Abstract: TIP30 is a putative tumor suppressor that can promote apoptosis and inhibit angiogenesis. However, the role of TIP30 in esophageal squamous cell carcinoma (ESCC) biology has not been investigated. Immunohistochemistry was used to investigate the expression of TIP30 in 70 ESCC. Hypermethylation of TIP30 was evaluated by the methylation specific PCR (MSP) method in ESCC (tumor and paired adjacent non-tumor tissues). Lost expression of TIP30 was observed in 50 of 70 (71.4%) ESCC. 61.4% (43 of 70) of primary tumors analyzed displayed TIP30 hypermethylation, indicating that this aberrant characteristic is common in ESCC. Moreover, a statistically significant inverse association was found between TIP30 methylation status and expression of the TIP30 protein in tumor tissues (p = 0.001). We also found that microRNA-10b (miR-10b) targets a homologous DNA region in the 3′untranslated region of the TIP30 gene and represses its expression at the transcriptional level. Reporter assay with 3′UTR of TIP30 cloned downstream of the luciferase gene showed reduced luciferase activity in the presence of miR-10b, providing strong evidence that miR-10b is a direct regulator of TIP30. These results suggest that TIP30 expression is regulated by promoter methylation and miR-10b in ESCC.

  18. Compact stars in f(R, T) gravity

    Energy Technology Data Exchange (ETDEWEB)

    Das, Amit; Guha, B.K. [Indian Institute of Engineering Science and Technology, Department of Physics, Howrah, West Bengal (India); Rahaman, Farook [Jadavpur University, Department of Mathematics, Kolkata, West Bengal (India); Ray, Saibal [Government College of Engineering and Ceramic Technology, Department of Physics, Kolkata, West Bengal (India)

    2016-12-15

    In the present paper we generate a set of solutions describing the interior of a compact star under f(R, T) theory of gravity which admits conformal motion. An extension of general relativity, the f(R, T) gravity is associated to Ricci scalar R and the trace of the energy-momentum tensor T. To handle the Einstein field equations in the form of differential equations of second order, first of all we adopt the Lie algebra with conformal Killing vectors (CKV) which enable one to get a solvable form of such equations and second we consider the equation of state (EOS) p = ωρ with 0 < ω < 1 for the fluid distribution consisting of normal matter, ω being the EOS parameter. We therefore analytically explore several physical aspects of the model to represent behavior of the compact stars such as - energy conditions, TOV equation, stability of the system, Buchdahl condition, compactness and redshift. It is checked that the physical validity and the acceptability of the present model within the specified observational constraint in connection to a dozen of the compact star candidates are quite satisfactory. (orig.)

  19. Brane f(R) gravity and the dark side of the universe

    International Nuclear Information System (INIS)

    Borzou, A.; Sepangi, H. R.; Shahidi, S.; Yousefi, R.

    2009-01-01

    We consider a brane world scenario in which the bulk action is assumed to have the form of a generic function of the Ricci scalar f(R) and derive the resulting Einstein field equation on the brane. In a constant curvature bulk a conserved geometric quantity appears in the field equations which can be associated with matter. We present spherically symmetric solutions which account for galaxy rotation curves in a specific form. Then cosmological solutions by assuming a specific form for f(R) are derived which can explain an accelerated expanding universe.

  20. 49 CFR 570.61 - Suspension system.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 6 2010-10-01 2010-10-01 false Suspension system. 570.61 Section 570.61... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION VEHICLE IN USE INSPECTION STANDARDS Vehicles With GVWR of More Than 10,000 Pounds § 570.61 Suspension system. (a) Suspension condition. Ball joint seals shall not be cut...

  1. A complex molecular interplay of auxin and ethylene signaling pathways is involved in Arabidopsis growth promotion by Burkholderia phytofirmans PsJN

    Directory of Open Access Journals (Sweden)

    María Josefina Poupin

    2016-04-01

    Full Text Available Modulation of phytohormones homeostasis is one of the proposed mechanisms to explain plant growth promotion induced by beneficial rhizobacteria (PGPR. However, there is still limited knowledge about the molecular signals and pathways underlying these beneficial interactions. Even less is known concerning the interplay between phytohormones in plants inoculated with PGPR. Auxin and ethylene are crucial hormones in the control of plant growth and development, and recent studies report an important and complex crosstalk between them in the regulation of different plant developmental processes. The objective of this work was to study the role of both hormones in the growth promotion of Arabidopsis thaliana plants induced by the well-known PGPR Burkholderia phytofirmans PsJN. For this, the spatiotemporal expression patterns of several genes related to auxin biosynthesis, perception and response and ethylene biosynthesis were studied, finding that most of these genes showed specific transcriptional regulations after inoculation in roots and shoots. PsJN-growth promotion was not observed in Arabidopsis mutants with an impaired ethylene (ein2-1 or auxin (axr1-5 signaling. Even, PsJN did not promote growth in an ethylene overproducer (eto2, indicating that a fine regulation of both hormones signaling and homeostasis is necessary to induce growth of the aerial and root tissues. Auxin polar transport is also involved in growth promotion, since PsJN did not promote primary root growth in the pin2 mutant or under chemical inhibition of transport in wild type plants. Finally, a key role for ethylene biosynthesis was found in the PsJN-mediated increase in root hair number. These results not only give new insights of PGPR regulation of plant growth but also are also useful to understand key aspects of Arabidopsis growth control.

  2. Effects of the plant growth-promoting bacterium Burkholderia phytofirmans PsJN throughout the life cycle of Arabidopsis thaliana.

    Directory of Open Access Journals (Sweden)

    María Josefina Poupin

    Full Text Available Plant growth-promoting rhizobacteria (PGPR induce positive effects in plants, such as increased growth or reduced stress susceptibility. The mechanisms behind PGPR/plant interaction are poorly understood, as most studies have described short-term responses on plants and only a few studies have analyzed plant molecular responses under PGPR colonization. Here, we studied the effects of the PGPR bacterial model Burkholderiaphytofirmans PsJN on the whole life cycle of Arabidopsis thaliana plants. We reported that at different plant developmental points, strain PsJN can be found in the rhizosphere and also colonizing their internal tissues. In early ontogeny, strain PsJN increased several growth parameters and accelerated growth rate of the plants. Also, an Arabidopsis transcriptome analysis revealed that 408 genes showed differential expression in PsJN-inoculated plants; some of these genes are involved in stress response and hormone pathways. Specifically, genes implicated in auxin and gibberellin pathways were induced. Quantitative transcriptional analyses of selected genes in different developmental stages revealed that the beginning of these changes could be evidenced early in development, especially among the down-regulated genes. The inoculation with heat-killed bacteria provoked a more severe transcriptional response in plants, but was not able to induce plant growth-promotion. Later in ontogeny, the growth rates of inoculated plants decreased with respect to the non-inoculated group and, interestingly, the inoculation accelerated the flowering time and the appearance of senescence signs in plants; these modifications correlate with the early up-regulation of flowering control genes. Then, we show that a single inoculation with a PGPR could affect the whole life cycle of a plant, accelerating its growth rate and shortening its vegetative period, both effects relevant for most crops. Thus, these findings provide novel and interesting aspects

  3. Study of some chaotic inflationary models in f(R) gravity

    Science.gov (United States)

    Sharif, M.; Nawazish, Iqra

    2018-04-01

    In this paper, we discuss an inflationary scenario via scalar field and fluid cosmology for an anisotropic homogeneous universe model in f(R) gravity. We consider an equation of state which corresponds to a quasi-de Sitter expansion and investigate the effect of the anisotropy parameter for different values of the deviation parameter. We evaluate potential models like linear, quadratic and quartic models which correspond to chaotic inflation. We construct the observational parameters for a power-law model of f(R) gravity and construct the graphical analysis of tensor-scalar ratio and spectral index which indicates the consistency of these parameters with Planck 2015 data.

  4. Equation of state of charged latex suspensions

    International Nuclear Information System (INIS)

    Reus, Valerie

    1995-01-01

    We measured the osmotic pressure of charged bromo-polystyrene particles suspensions in the dilute System (0,01-10% in volume fraction). The typical range of differences in water heights varies from one millimeter to a few centimeters. When particles are polydisperse, samples remain always sols but if particles are monodisperse, they can form supramolecular crystals stabilized by electrostatic repulsions. These crystals exist only when the ionic force is very low, about one μmole/l. We determined the structure of these assemblies by light and X-ray scattering as function of the volume fraction. At low volume fractions, crystals adopt a body centered cubic structure; when the concentration increases, they become more compact and we observe face centered cubic structures. After shearing, defects may appear and two dimensional hexagonal structures can be found. This type of study of the osmotic pressure versus distance (in the range 300 nm) is equivalent to a highly precise atomic force measurement, since it allows detection of forces as small as 10 -11 -10 -12 N. (author) [fr

  5. Revisiting van der Waals like behavior of f(R AdS black holes via the two point correlation function

    Directory of Open Access Journals (Sweden)

    Jie-Xiong Mo

    2017-05-01

    Full Text Available Van der Waals like behavior of f(R AdS black holes is revisited via two point correlation function, which is dual to the geodesic length in the bulk. The equation of motion constrained by the boundary condition is solved numerically and both the effect of boundary region size and f(R gravity are probed. Moreover, an analogous specific heat related to δL is introduced. It is shown that the T−δL graphs of f(R AdS black holes exhibit reverse van der Waals like behavior just as the T−S graphs do. Free energy analysis is carried out to determine the first order phase transition temperature T⁎ and the unstable branch in T−δL curve is removed by a bar T=T⁎. It is shown that the first order phase transition temperature is the same at least to the order of 1010 for different choices of the parameter b although the values of free energy vary with b. Our result further supports the former finding that charged f(R AdS black holes behave much like RN-AdS black holes. We also check the analogous equal area law numerically and find that the relative errors for both the cases θ0=0.1 and θ0=0.2 are small enough. The fitting functions between log⁡|T−Tc| and log⁡|δL−δLc| for both cases are also obtained. It is shown that the slope is around 3, implying that the critical exponent is about 2/3. This result is in accordance with those in former literatures of specific heat related to the thermal entropy or entanglement entropy.

  6. 76 FR 10430 - BNSF Railway Company-Temporary Trackage Rights Exemption-Union Pacific Railroad Company

    Science.gov (United States)

    2011-02-24

    .... The trackage rights are temporary in nature and are scheduled to expire at midnight on December 10... days before the exemption becomes effective). An original and 10 copies of all pleadings, referring to..., DC 20423-0001. In addition, a copy of each pleading must be served on Karl Morell, Of Counsel, Ball...

  7. THE SUSPENSION OF CRIMINAL INVESTIGATION IN THE EVENT OF INCIDENCE OF A TEMPORARY LEGAL IMPEDIMENT

    Directory of Open Access Journals (Sweden)

    Nadia Claudia CANTEMIR – STOICA

    2018-05-01

    Full Text Available The criminal investigation is the first stage of the criminal proceeding, necessary to be carried out under legality, so as to collect the necessary evidence to find the truth in order to prosecute or not to prosecute a person subject to the criminal investigation. Sometimes, depending on the quality at the time the criminal offense was committed or on the occasion of the investigations, it is not possible to order the criminal proceedings to be initiated, given that there is a temporary legal impediment. The present study aims to bring to the debate the theoretical and practical elements regarding the institution of temporary legal impediment

  8. 46 CFR 112.01-15 - Temporary emergency power source.

    Science.gov (United States)

    2010-10-01

    ... EMERGENCY LIGHTING AND POWER SYSTEMS Definitions of Emergency Lighting and Power Systems § 112.01-15 Temporary emergency power source. A temporary emergency power source is one of limited capacity that carries... 46 Shipping 4 2010-10-01 2010-10-01 false Temporary emergency power source. 112.01-15 Section 112...

  9. Evaluating item endorsement rates for the MMPI-2-RF F-r and Fp-r scales across ethnic, gender, and diagnostic groups with a forensic inpatient sample.

    Science.gov (United States)

    Glassmire, David M; Jhawar, Amandeep; Burchett, Danielle; Tarescavage, Anthony M

    2017-05-01

    The Minnesota Multiphasic Personality Inventory-2 (MMPI-2) F(p) (Infrequency-Psychopathology) scale was developed to measure overreporting in a manner that was minimally confounded by genuine psychopathology, which was a problem with using the MMPI-2 F (Infrequency) scale among patients with severe mental illness. Although revised versions of both of these scales are included on the MMPI-2-Restructured Form and used in a forensic context, no item-level research has been conducted on their sensitivity to genuine psychopathology among forensic psychiatric inpatients. Therefore, we examined the psychometric properties of the scales in a sample of 438 criminally committed forensic psychiatric inpatients who were adjudicated as not guilty by reason of insanity and had no known incentive to overreport. We found that 20 of the 21 Fp-r items (95.2%) demonstrated endorsement rates ≤ 20%, with 14 of the items (66.7%) endorsed by less than 10% of the sample. Similar findings were observed across genders and across patients with mood and psychotic disorders. The one item endorsed by more than 20% of the sample had a 23.7% overall endorsement rate and significantly different endorsement rates across ethnic groups, with the highest endorsements occurring among Hispanic/Latino (43.3% endorsement rate) patients. Endorsement rates of F-r items were generally higher than for Fp-r items. At the scale level, we also examined correlations with the Restructured Clinical Scales and found that Fp-r demonstrated lower correlations than F-r, indicating that Fp-r is less associated with a broad range of psychopathology. Finally, we found that Fp-r demonstrated slightly higher specificity values than F-r at all T score cutoffs. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

  10. Interrelation of androgen receptor and miR-30a and miR-30a function in ER-, PR-, AR+ MDA-MB-453 breast cancer cells.

    Science.gov (United States)

    Lyu, Shuhua; Liu, Han; Liu, Xia; Liu, Shan; Wang, Yahong; Yu, Qi; Niu, Yun

    2017-10-01

    The association between androgen-induced androgen receptor (AR) activating signal and microRNA (miR)-30a was investigated, as well as the function of miR-30a in estrogen receptor-negative (ER - ), progesterone receptor-negative (PR - ), and AR-positive (AR + ) MDA-MB-453 breast cancer cells. Androgen-induced AR activating signal upregulated the expression of AR, and downregulated the expression of miR-30a, b and c. Bioinformatics analysis indicated a putative miR-30a, b and c binding site in the 3'-untranslated region of AR mRNA. It was confirmed that the AR gene is a direct target of miR-30a, whereas AR does not target the miR-30a promoter, and AR activating signal may indirectly downregulate miR-30a through other cell signaling pathways. In this positive feedback mechanism AR is then upregulated through miR-30a. Overexpression of miR-30a inhibited cell proliferation, whereas inhibition of miR-30a expression by specific antisense oligonucleotides, increased cell growth. Previously, androgen-induced AR activating signal was demonstrated to inhibit cell proliferation in ER - , PR - and AR + MDA-MB-453 breast cancer cells, but AR activating signal downregulated the expression of miR-30a, relieving the inhibition of MDA-MB-453 cell growth. Therefore, in MDA-MB-453 breast cancer cells, miR-30a has two different functions regarding cell growth: Inhibition of cell proliferation through a positive feedback signaling pathway; and the relative promotion of cell proliferation through downregulation of miR-30a. Thus, the association between AR activating signal and microRNAs is complex, and microRNAs may possess different functions due to different signaling pathways. Although the results of the present study were obtained in one cell line, they contribute to subsequent studies on ER - , PR - and AR + breast cancer.

  11. Importprocessen för inrednings- och gåvoartiklar från USA till Finland : En handbok för företagaren

    OpenAIRE

    Smeds, Desiré; Backlund, Johanna

    2016-01-01

    Det här examensarbetet handlar om import från USA med fokus på inrednings- och gåvoartiklar. I arbetet lyfter vi steg för steg fram de delar som utgör importprocessen hela vägen från hur man hittar en pålitlig leverantör till förtullningen av produkterna här i Finland. Syftet med arbetet är att det skall kunna fungera som en handbok för företag som vill starta en småskalig importverksamhet av inrednings- och gåvoartiklar. Vi tar även upp information om import och internationell handel i a...

  12. 76 FR 41855 - Columbus Geographic Systems (GIS) Ltd.; Order of Suspension of Trading

    Science.gov (United States)

    2011-07-15

    ... SECURITIES AND EXCHANGE COMMISSION [File No. 500-1] Columbus Geographic Systems (GIS) Ltd.; Order of Suspension of Trading July 13, 2011. It appears to the Securities and Exchange Commission that... Systems (GIS) Ltd. because it has not filed any periodic reports since the period ended June 30, 2008. The...

  13. Wormholes in viable f(R) modified theories of gravity and weak energy condition

    Energy Technology Data Exchange (ETDEWEB)

    Pavlovic, Petar [Universitaet Hamburg, II. Institut fuer Theoretische Physik, Hamburg (Germany); Sossich, Marko [University of Zagreb, Department of Physics, Faculty of Electrical Engineering and Computing, Zagreb (Croatia)

    2015-03-01

    In this work wormholes in viable f(R) gravity models are analyzed. We are interested in exact solutions for stress-energy tensor components depending on different shape and redshift functions. Several solutions of gravitational equations for different f(R) models are examined. The solutions found imply no need for exotic material, while this need is implied in the standard general theory of relativity. A simple expression for weak energy condition (WEC) violation near the throat is derived and analyzed. High curvature regime is also discussed, as well as the question of the highest possible values of the Ricci scalar for which the WEC is not violated near the throat, and corresponding functions are calculated for several models. The approach here differs from the one that has been common since no additional assumptions to simplify the equations have been made, and the functions in f(R) models are not considered to be arbitrary functions, but rather a feature of the theory that has to be evaluated on the basis of consistency with observations for the Solar System and cosmological evolution. Therefore in this work we show that the existence of wormholes without exotic matter is not only possible in simple arbitrary f(R) models, but also in models that are in accordance with empirical data. (orig.)

  14. Usefulness of oral loading of oxcarbazepine suspension in selected patients with epilepsy.

    Science.gov (United States)

    Kim, Dong Wook; Gu, Namyi; Lee, Howard; Jang, In-Jin; Chu, Kon; Yu, Kyung-Sang; Cho, Joo-Youn; Yoon, Seo Hyun; Na, Hyun Jeong; Lee, Sang Kun

    2013-10-01

    Oral loading of oxcarbazepine tablet is effective and well tolerated to adequately achieve the therapeutic levels of its active metabolite, 10,11-dihydro-10-hydroxy-carbazepine (monohydroxy derivative, MHD) in epilepsy patients. The present study was performed to investigate the safety, tolerability, and pharmacokinetic profiles of oral loading of oxcarbazepine suspension in epilepsy patients with a high risk of recurrent seizures. Oxcarbazepine suspension was administered orally at a single loading dose of 30 mg/kg to 38 adult patients with recurrent seizures, who required rapid seizure control or temporarily discontinued antiepileptic drugs for diagnostic or pre-surgical evaluation. Plasma concentrations of oxcarbazepine and MHD were determined, and adverse events were assessed at 2, 4, 6, 8, 10, 12, 14, 16, and 24 hours after oral loading of oxcarbazepine suspension. 30 patients experienced ≥ 1 adverse event during the first 24 hours after oral loading of oxcarbazepine (e.g., dizziness, transient diplopia, nausea or vomiting), most of which occurred within 4 hours after loading, suggesting no temporal association with MHD plasma levels. 35 (92.1%) patients were still compliant with a maintenance dose of oxcarbazepine after discharge from hospital. 34 (89.4%) patients reached the lower therapeutic level of MHD (12 mg/l) at 4 hours after oral loading of oxcarbazepine suspension, which lasted up to 24 hours in most patients. No patient reached the supratherapeutic levels of MHD (> 35 mg/l) during the study. The mean plasma concentration-time curves and pharmacokinetic profiles of oral loading of oxcarbazepine suspension were similar to those of oral loading of oxcarbazepine tablet. Oral loading of oxcarbazepine suspension followed by maintenance dosing is well tolerated and effective in steadily achieving the therapeutic level of MHD in selected patients with epilepsy.

  15. 76 FR 34080 - Agency Information Collection Activities; Proposed Collection; Comment Request; Temporary...

    Science.gov (United States)

    2011-06-10

    ...] Agency Information Collection Activities; Proposed Collection; Comment Request; Temporary Marketing... appropriate, and other forms of information technology. Temporary Marketing Permit Applications--21 CFR 130.17... submitted recent requests for temporary marketing permits. Based on this information, we estimate that there...

  16. Prevalence of temporary social security benefits due to respiratory disease in Brazil.

    Science.gov (United States)

    Ildefonso, Simone de Andrade Goulart; Barbosa-Branco, Anadergh; Albuquerque-Oliveira, Paulo Rogério

    2009-01-01

    To determine the prevalence of temporary social security benefits due to respiratory disease granted to employees, as well as the number of lost workdays and costs resulting from those in Brazil between 2003 and 2004. Cross-sectional study using data obtained from the Unified System of Benefits of the Brazilian Institute of Social Security (INSS, Instituto Nacional de Seguro Social) and the Brazilian Social Registry Database. Data regarding gender, age, diagnosis and type of economic activity, as well as type, duration and cost of benefits, were compiled. Respiratory diseases accounted for 1.3% of the total number of temporary social security benefits granted by INSS, with a prevalence rate of 9.92 (per 10,000 employment contracts). Females and individuals older than 50 years of age were the most affected. Non-work-related benefits were more common than were work-related benefits. The most prevalent diseases were pneumonia, asthma and COPD, followed by laryngeal and vocal cord diseases. The most prevalent types of economic activity were auxiliary transportation equipment manufacturing, tobacco product manufacturing and computer-related activities. The mean duration of benefits was 209.68 days, with a mean cost of R$ 4,495.30 per occurrence. Respiratory diseases caused by exogenous agents demanded longer sick leave (mean, 296.72 days) and greater cost (mean, R$ 7,105.74). The most prevalent diseases were airway diseases and pneumonia. Workers from auxiliary transportation equipment manufacturing, tobacco product manufacturing and computer-related activities were the most affected. Diseases caused by exogenous agents demanded longer sick leaves and resulted in greater costs.

  17. 78 FR 44965 - Notice of Temporary Closure and Temporary Restrictions of Specific Uses on Public Lands for the...

    Science.gov (United States)

    2013-07-25

    ... individual during normal business hours. The FIRS is available 24 hours a day, 7 days a week, to leave a... provide law enforcement officers to work at the event. The temporary closure and temporary restrictions...) Weapon means a firearm, compressed gas or spring powered pistol or rifle, bow and arrow, cross bow...

  18. 49 CFR 570.8 - Suspension systems.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 6 2010-10-01 2010-10-01 false Suspension systems. 570.8 Section 570.8 Transportation Other Regulations Relating to Transportation (Continued) NATIONAL HIGHWAY TRAFFIC SAFETY... Pounds or Less § 570.8 Suspension systems. (a) Suspension condition. Ball joint seals shall not be cut or...

  19. 75 FR 1118 - BNSF Railway Company-Temporary Trackage Rights Exemption-Union Pacific Railroad Company

    Science.gov (United States)

    2010-01-08

    ... trackage rights are temporary in nature and are for a period from January 22, 2010 through December 10... effective). An original and 10 copies of all pleadings, referring to STB Finance Docket No. 35340, must be..., a copy of each pleading must be served on Adrian L. Steel, Jr., Mayer Brown LLP, 1999 K Street, NW...

  20. On reactive suspension plasma spraying of calcium titanate

    Czech Academy of Sciences Publication Activity Database

    Kotlan, Jiří; Pala, Zdeněk; Mušálek, Radek; Ctibor, Pavel

    2016-01-01

    Roč. 42, č. 3 (2016), s. 4607-4615 ISSN 0272-8842 R&D Projects: GA ČR GA15-12145S Institutional support: RVO:61389021 Keywords : Suspensions * X-raymethods * Perovskites * Substrates * Suspension plasma spraying Subject RIV: JH - Ceramics, Fire-Resistant Materials and Glass Impact factor: 2.986, year: 2016 http://www.sciencedirect.com/science/article/pii/S0272884215022646

  1. Investigation of Strouhal numbers of iced cable models of cable-supported bridges with respect to angle of wind attack

    Czech Academy of Sciences Publication Activity Database

    Górski, P.; Tatara, M.; Pospíšil, Stanislav; Kuznetsov, Sergeii; Marušić, A.

    2015-01-01

    Roč. 112, 2-B (2015), s. 417-432 ISSN 1897-628X R&D Projects: GA MŠk(CZ) LO1219; GA MPO(CZ) FR-TI3/654 Keywords : bridge cable * ice accretion * Strouhal number * angle of attack * vortex shedding frequency Subject RIV: JN - Civil Engineering http://suw.biblos.pk.edu.pl/resources/i5/i6/i6/i8/i4/r56684/GorskiP_InvestigationsStrouhal.pdf

  2. 78 FR 75201 - Suspension of Limitations Under the Jerusalem Embassy Act

    Science.gov (United States)

    2013-12-10

    ... Vol. 78 Tuesday, No. 237 December 10. 2013 Part IV The President Presidential Determination No. 2014-04 of December 3, 2013--Suspension of Limitations Under the Jerusalem Embassy Act Proclamation 9067--Death of Nelson Mandela Proclamation 9068--National Pearl Harbor Remembrance Day, 2013 Memorandum...

  3. Harmonic decomposition of magneto-optical signal from suspensions of superparamagnetic nanoparticles

    Science.gov (United States)

    Patterson, Cody; Syed, Maarij; Takemura, Yasushi

    2018-04-01

    Magnetic nanoparticles (MNPs) are widely used in biomedical applications. Characterizing dilute suspensions of superparamagnetic iron oxide nanoparticles (SPIONs) in bio-relevant media is particularly valuable for magnetic particle imaging, hyperthermia, drug delivery, etc. Here, we study dilute aqueous suspensions of single-domain magnetite nanoparticles using an AC Faraday rotation (FR) setup. The setup uses an oscillating magnetic field (800 Hz) which generates a multi-harmonic response. Each harmonic is collected and analyzed using the Fourier components of the theoretical signal determined by a Langevin-like magnetization. With this procedure, we determine the average magnetic moment per particle μ , particle number density n, and Verdet constant of the sample. The fitted values of μ and n are shown to be consistent across each harmonic. Additionally, we present the results of these parameters as n is varied. The large values of μ reveal the possibility of clustering as reported in other literature. This suggests that μ is representative of the average magnetic moment per cluster of nanoparticles. Multiple factors, including the external magnetic field, surfactant degradation, and laser absorption, can contribute to dynamic and long-term aggregation leading to FR signals that represent space- and time-averaged sample parameters. Using this powerful analysis procedure, future studies are aimed at determining the clustering mechanisms in this AC system and characterizing SPION suspensions at different frequencies and viscosities.

  4. Suspensions Plasma Spraying of Ceramics with Hybrid Water-Stabilized Plasma Technology

    Czech Academy of Sciences Publication Activity Database

    Mušálek, Radek; Medřický, Jan; Tesař, T.; Kotlan, Jiří; Pala, Zdeněk; Lukáč, František; Chráska, Tomáš; Curry, N.

    2017-01-01

    Roč. 26, 1-2 (2017), s. 37-46 ISSN 1059-9630. [ISTC 2016: International Thermal Spray Conference. Shanghai, 10.05.2016-12.05.2016] R&D Projects: GA ČR GA15-12145S Institutional support: RVO:61389021 Keywords : alumina * ceramics * dense * hybrid plasma torch * suspension plasma spraying * water-stabilized plasma * yttria-stabilized zirconia (YSZ) Subject RIV: JK - Corrosion ; Surface Treatment of Materials OBOR OECD: Coating and films Impact factor: 1.488, year: 2016 http://link.springer.com/article/10.1007/s11666-016-0493-6

  5. High-level production of human interleukin-10 fusions in tobacco cell suspension cultures

    Science.gov (United States)

    Kaldis, Angelo; Ahmad, Adil; Reid, Alexandra; McGarvey, Brian; Brandle, Jim; Ma, Shengwu; Jevnikar, Anthony; Kohalmi, Susanne E; Menassa, Rima

    2013-01-01

    The production of pharmaceutical proteins in plants has made much progress in recent years with the development of transient expression systems, transplastomic technology and humanizing glycosylation patterns in plants. However, the first therapeutic proteins approved for administration to humans and animals were made in plant cell suspensions for reasons of containment, rapid scale-up and lack of toxic contaminants. In this study, we have investigated the production of human interleukin-10 (IL-10) in tobacco BY-2 cell suspension and evaluated the effect of an elastin-like polypeptide tag (ELP) and a green fluorescent protein (GFP) tag on IL-10 accumulation. We report the highest accumulation levels of hIL-10 obtained with any stable plant expression system using the ELP fusion strategy. Although IL-10-ELP has cytokine activity, its activity is reduced compared to unfused IL-10, likely caused by interference of ELP with folding of IL-10. Green fluorescent protein has no effect on IL-10 accumulation, but examining the trafficking of IL-10-GFP over the cell culture cycle revealed fluorescence in the vacuole during the stationary phase of the culture growth cycle. Analysis of isolated vacuoles indicated that GFP alone is found in vacuoles, while the full-size fusion remains in the whole-cell extract. This indicates that GFP is cleaved off prior to its trafficking to the vacuole. On the other hand, IL-10-GFP-ELP remains mostly in the ER and accumulates to high levels. Protein bodies were observed at the end of the culture cycle and are thought to arise as a consequence of high levels of accumulation in the ER. PMID:23297698

  6. Pärimuslik ajalugu ja Fr. R. Kreutzwald / Tiiu Jaago

    Index Scriptorium Estoniae

    Jaago, Tiiu, 1960-

    2005-01-01

    Pärimuslik ajalugu kui rahvapärane ajalookäsitus, mida saab uurida folkloorse jutustamise kaudu. Fr. R. Kreutzwaldi ja F. K. H. Kruse sõnavõttudest Aruküla koobaste päritolu kohta ajakirjas "Das Inland" aastast 1844

  7. Dynamical analysis of cylindrically symmetric anisotropic sources in f(R, T) gravity

    Energy Technology Data Exchange (ETDEWEB)

    Zubair, M.; Azmat, Hina [COMSATS Institute of Information Technology, Department of Mathematics, Lahore (Pakistan); Noureen, Ifra [University of Management and Technology, Department of Mathematics, Lahore (Pakistan)

    2017-03-15

    In this paper, we have analyzed the stability of cylindrically symmetric collapsing object filled with locally anisotropic fluid in f(R, T) theory, where R is the scalar curvature and T is the trace of stress-energy tensor of matter. Modified field equations and dynamical equations are constructed in f(R, T) gravity. The evolution or collapse equation is derived from dynamical equations by performing a linear perturbation on them. The instability range is explored in both the Newtonian and the post-Newtonian regimes with the help of an adiabatic index, which defines the impact of the physical parameters on the instability range. Some conditions are imposed on the physical quantities to secure the stability of the gravitating sources. (orig.)

  8. Correlated particle dynamics in concentrated quasi-two-dimensional suspensions

    International Nuclear Information System (INIS)

    Diamant, H; Cui, B; Lin, B; Rice, S A

    2005-01-01

    We investigate theoretically and experimentally how the hydrodynamically correlated lateral motion of particles in a suspension confined between two surfaces is affected by the suspension concentration. Despite the long range of the correlations (decaying as 1/r 2 with the inter-particle distance r), the concentration effect is present only at short inter-particle distances for which the static pair correlation is nonuniform. This is in sharp contrast with the effect of hydrodynamic screening in unconfined suspensions, where increasing the concentration changes the prefactor of the large-distance correlation

  9. Från outsiderfilmmakare till etablerad indieregissör : David Lynch, Jim Jarmusch och Steven Soderbergh

    OpenAIRE

    Simberg, Maximilian

    2014-01-01

    Det här arbetet behandlar kreativ frihet och konstnärligt oberoende i filmskapande, utgående från begreppet independent film och regissörerna David Lynch, Jim Jarmusch och Steven Soderbergh. Den centrala frågeställningen är hur det har varit möjligt för en filmkonstnär att uppnå konstnärligt oberoende och samtidigt ha en långlivad och framgångsrik karriär. Arbetets fokus ligger på de tre regissörernas genombrottsfilmer; Eraserhead, Stranger Than Paradise och sex, lies, and videotape, och förs...

  10. 47 CFR 25.277 - Temporary fixed earth station operations.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 2 2010-10-01 2010-10-01 false Temporary fixed earth station operations. 25.277 Section 25.277 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES SATELLITE COMMUNICATIONS Technical Operations § 25.277 Temporary fixed earth station operations...

  11. New proposal for non-linear ghost-free massive F(R) gravity: Cosmic acceleration and Hamiltonian analysis

    International Nuclear Information System (INIS)

    Klusoň, Josef; Nojiri, Shin'ichi; Odintsov, Sergei D.

    2013-01-01

    We propose new version of massive F(R) gravity which is natural generalization of convenient massive ghost-free gravity. Its Hamiltonian formulation in scalar-tensor frame is developed. We show that such F(R) theory is ghost-free. The cosmological evolution of such theory is investigated. Despite the strong Bianchi identity constraint the possibility of cosmic acceleration (especially, in the presence of cold dark matter) is established. Ghost-free massive F(R,T) gravity is also proposed

  12. 30 CFR 77.601 - Trailing cables or portable cables; temporary splices.

    Science.gov (United States)

    2010-07-01

    ... LABOR COAL MINE SAFETY AND HEALTH MANDATORY SAFETY STANDARDS, SURFACE COAL MINES AND SURFACE WORK AREAS OF UNDERGROUND COAL MINES Trailing Cables § 77.601 Trailing cables or portable cables; temporary... or splices that heat or spark under load shall not be used. ...

  13. Solar System constraints on a cosmologically viable f(R) theory

    Energy Technology Data Exchange (ETDEWEB)

    Bisabr, Yousef, E-mail: y-bisabr@srttu.ed [Department of Physics, Shahid Rajaee Teacher Training University, Lavizan, Tehran 16788 (Iran, Islamic Republic of)

    2010-01-18

    Recently, a model f(R) theory is proposed (Miranda et al. (2009)) which is cosmologically viable and distinguishable from LAMBDACDM. We use chameleon mechanism to investigate viability of the model in terms of Solar System experiments.

  14. Study of Antigravity in an F(R) Model and in Brans-Dicke Theory with Cosmological Constant

    OpenAIRE

    Oikonomou, V. K.; Karagiannakis, N.

    2014-01-01

    We study antigravity, that is having an effective gravitational constant with a negative sign, in scalar-tensor theories originating from $F(R)$-theory and in a Brans-Dicke model with cosmological constant. For the $F(R)$ theory case, we obtain the antigravity scalar-tensor theory in the Jordan frame by using a variant of the Lagrange multipliers method and we numerically study the time dependent effective gravitational constant. As we shall demonstrate by using a specific $F(R)$ model, altho...

  15. Solar System constraints on a cosmologically viable f(R) theory

    International Nuclear Information System (INIS)

    Bisabr, Yousef

    2010-01-01

    Recently, a model f(R) theory is proposed (Miranda et al. (2009)) which is cosmologically viable and distinguishable from ΛCDM. We use chameleon mechanism to investigate viability of the model in terms of Solar System experiments.

  16. 75 FR 27362 - Notice of Temporary Order Restricting Dogs From Public Lands in the Kasha-Katuwe Tent Rocks...

    Science.gov (United States)

    2010-05-14

    ... Temporary Order Restricting Dogs From Public Lands in the Kasha-Katuwe Tent Rocks National Monument in... dogs from public lands within the 5,610- acre Kasha-Katuwe Tent Rocks National Monument. This order... persons with dogs is prohibited on public land in New Mexico Prime Meridian, T. 16 N., R. 5 E., and T. 17...

  17. 75 FR 51379 - Safety Zone; Celebrate Erie, Presque Isle Bay, Erie, PA

    Science.gov (United States)

    2010-08-20

    ... display. DATES: This rule is effective from 9:30 p.m. until 10:30 p.m. on August 22, 2010. ADDRESSES...: Temporary final rule. SUMMARY: The Coast Guard is establishing a temporary safety zone on Presque Isle Bay... Presque Isle Bay in Erie, PA during the Celebrate Erie fireworks display, August 22, 2010. This temporary...

  18. Influence of f(R) models on the existence of anisotropic self-gravitating systems

    Energy Technology Data Exchange (ETDEWEB)

    Yousaf, Z.; Sharif, M.; Bhatti, M.Z. [University of the Punjab, Department of Mathematics, Lahore (Pakistan); Ilyas, M. [University of the Punjab, Centre for High Energy Physics, Lahore (Pakistan)

    2017-10-15

    This paper aims to explore some realistic configurations of anisotropic spherical structures in the background of metric f(R) gravity, where R is the Ricci scalar. The solutions obtained by Krori and Barua are used to examine the nature of particular compact stars with three different modified gravity models. The behavior of material variables is analyzed through plots and the physical viability of compact stars is investigated through energy conditions. We also discuss the behavior of different forces, equation of state parameter, measure of anisotropy and Tolman-Oppenheimer-Volkoff equation in the modeling of stellar structures. The comparison from our graphical representations may provide evidence for the realistic and viable f(R) gravity models at both theoretical and the astrophysical scale. (orig.)

  19. Constraining models of f(R) gravity with Planck and WiggleZ power spectrum data

    International Nuclear Information System (INIS)

    Dossett, Jason; Parkinson, David; Hu, Bin

    2014-01-01

    In order to explain cosmic acceleration without invoking ''dark'' physics, we consider f(R) modified gravity models, which replace the standard Einstein-Hilbert action in General Relativity with a higher derivative theory. We use data from the WiggleZ Dark Energy survey to probe the formation of structure on large scales which can place tight constraints on these models. We combine the large-scale structure data with measurements of the cosmic microwave background from the Planck surveyor. After parameterizing the modification of the action using the Compton wavelength parameter B 0 , we constrain this parameter using ISiTGR, assuming an initial non-informative log prior probability distribution of this cross-over scale. We find that the addition of the WiggleZ power spectrum provides the tightest constraints to date on B 0 by an order of magnitude, giving log 10 (B 0 ) < −4.07 at 95% confidence limit. Finally, we test whether the effect of adding the lensing amplitude A Lens and the sum of the neutrino mass ∑m ν is able to reconcile current tensions present in these parameters, but find f(R) gravity an inadequate explanation

  20. Experimental Evaluation of Mountain Bike Suspension Systems

    Directory of Open Access Journals (Sweden)

    J. Titlestad

    2003-01-01

    Full Text Available A significant distinction between competitive mountain bikes is whether they have a suspension system. Research studies indicate that a suspension system gives advantages, but it is difficult to quantify the benefits because they depend on so many variables, including the physiology and psychology of the cyclist, the roughness of the track and the design of the suspension system. A laboratory based test rig has been built that allows the number of variables in the system to be reduced and test conditions to be controlled. The test rig simulates regular impacts of the rear wheel with bumps in a rolling road. The physiological variables of oxygen consumption and heart rate were measured, together with speeds and forces at various points in the system. Physiological and mechanical test results both confirm a significant benefit in using a suspension system on the simulated rough track, with oxygen consumption reduced by around 30 % and power transmitted through the pedals reduced by 30 % to 60 %.

  1. Stability of an extemporaneously prepared alcohol-free phenobarbital suspension.

    Science.gov (United States)

    Cober, Mary Petrea; Johnson, Cary E

    2007-03-15

    The physical and chemical short-term stability of alcohol-free, oral suspensions of phenobarbital 10 mg/mL prepared from commercially available tablets in both a sugar and a sugar-free vehicle was assessed at room temperature. Phenobarbital oral suspension 10 mg/mL was prepared by crushing 10 60-mg tablets of phenobarbital with a mortar and pestle. A small amount of Ora-Plus was added to the phenobarbital powder to sufficiently wet the particles. A 1:1 mixture of Ora-Plus and either Ora-Sweet or Ora-Sweet SF was combined with the phenobarbital powder to produce a final volume of 60 mL. Three identical samples of each of the two different formulations were prepared and stored at room temperature in 2-oz amber plastic bottles. Immediately after preparation and at 15, 30, 60, and 115 days, the samples were assayed in duplicate by stability-indicating high-performance liquid chromatography. The samples were tasted and inspected for color and odor changes. The percent of the initial concentration remaining at each study time for each phenobarbital suspension was determined. Stability was defined as the retention of at least 90% of the initial concentration. There were no detectable changes in color, odor, and taste and no visible microbial growth in any sample. At least 98% of the initial phenobarbital concentration remained throughout the 115-day study period in both preparations. An extemporaneously prepared alcohol-free suspension of phenobarbital 10 mg/mL in a 1:1 mixture of Ora-Plus and Ora-Sweet or Ora-Sweet SF was stable for at least 115 days when stored in 2-oz amber plastic bottles at room temperature.

  2. Unified cosmic history in modified gravity: From F(R) theory to Lorentz non-invariant models

    Science.gov (United States)

    Nojiri, Shin'Ichi; Odintsov, Sergei D.

    2011-08-01

    The classical generalization of general relativity is considered as the gravitational alternative for a unified description of the early-time inflation with late-time cosmic acceleration. The structure and cosmological properties of a number of modified theories, including traditional F(R) and Hořava-Lifshitz F(R) gravity, scalar-tensor theory, string-inspired and Gauss-Bonnet theory, non-local gravity, non-minimally coupled models, and power-counting renormalizable covariant gravity are discussed. Different representations of and relations between such theories are investigated. It is shown that some versions of the above theories may be consistent with local tests and may provide a qualitatively reasonable unified description of inflation with the dark energy epoch. The cosmological reconstruction of different modified gravities is provided in great detail. It is demonstrated that eventually any given universe evolution may be reconstructed for the theories under consideration, and the explicit reconstruction is applied to an accelerating spatially flat Friedmann-Robertson-Walker (FRW) universe. Special attention is paid to Lagrange multiplier constrained and conventional F(R) gravities, for latter F(R) theory, the effective ΛCDM era and phantom divide crossing acceleration are obtained. The occurrences of the Big Rip and other finite-time future singularities in modified gravity are reviewed along with their solutions via the addition of higher-derivative gravitational invariants.

  3. Gravitational radiation in quadratic f(R) gravity

    International Nuclear Information System (INIS)

    Naef, Joachim; Jetzer, Philippe

    2011-01-01

    We investigate the gravitational radiation emitted by an isolated system for gravity theories with Lagrange density f(R)=R+aR 2 . As a formal result, we obtain leading order corrections to the quadrupole formula in general relativity. We make use of the analogy of f(R) theories with scalar-tensor theories, which in contrast to general relativity feature an additional scalar degree of freedom. Unlike general relativity, where the leading order gravitational radiation is produced by quadrupole moments, the additional degree of freedom predicts gravitational radiation of all multipoles, in particular, monopoles and dipoles, as this is the case for the most alternative gravity theories known today. An application to a hypothetical binary pulsar moving in a circular orbit yields the rough limit a 17 m 2 by constraining the dipole power to account at most for 1% of the quadrupole power as predicted by general relativity.

  4. Temporary labour contracts

    CERN Document Server

    2001-01-01

    At its September 2000 meeting, the Finance Committee approved a second one-year extension of the four existing temporary labour contracts (L020/PE, L021/PE, L022/PE, L023/PE) until 31 December 2001 for a total amount not exceeding 6 000 000 Swiss francs at 2000 prices. The Finance Committee is invited: - to take note that the estimated annual expenditure on temporary labour in 2001 will amount to approximately 4 500 000 Swiss francs against the previously estimated 6 000 000 Swiss francs; - to approve the extension of the four existing contracts by six months to 30 June 2002 for an overall amount not exceeding 1 500 000 Swiss francs; - to take note that new contracts for the Swiss part of the CERN site will be submitted for adjudication in December 2001 and that new contracts for the French part of the CERN site will be submitted for adjudication in the course of 2002.

  5. Solar system and equivalence principle constraints on f(R) gravity by the chameleon approach

    International Nuclear Information System (INIS)

    Capozziello, Salvatore; Tsujikawa, Shinji

    2008-01-01

    We study constraints on f(R) dark energy models from solar system experiments combined with experiments on the violation of the equivalence principle. When the mass of an equivalent scalar field degree of freedom is heavy in a region with high density, a spherically symmetric body has a thin shell so that an effective coupling of the fifth force is suppressed through a chameleon mechanism. We place experimental bounds on the cosmologically viable models recently proposed in the literature that have an asymptotic form f(R)=R-λR c [1-(R c /R) 2n ] in the regime R>>R c . From the solar system constraints on the post-Newtonian parameter γ, we derive the bound n>0.5, whereas the constraints from the violations of the weak and strong equivalence principles give the bound n>0.9. This allows a possibility to find the deviation from the Λ-cold dark matter (ΛCDM) cosmological model. For the model f(R)=R-λR c (R/R c ) p with 0 -10 , which shows that this model is hardly distinguishable from the ΛCDM cosmology

  6. 75 FR 63184 - Temporary Duty (TDY) Travel Allowances

    Science.gov (United States)

    2010-10-14

    ... GENERAL SERVICES ADMINISTRATION [Docket 2010-0009, Sequence 4] Temporary Duty (TDY) Travel Allowances AGENCY: Office of Governmentwide Policy, General Services Administration (GSA). ACTION: Notice of... agency travel programs, save money on travel costs, better protect the environment, and conserve natural...

  7. Health physics around a controlled fusion research device: the Tokamak at Fontenay-aux-Roses (T.F.R.)

    International Nuclear Information System (INIS)

    1977-01-01

    The X and neutron dosimetry measurement near the magnetic confinement device for hot plasma, called T.F.R. (Tokamak, Fontenay-aux-Roses) are presented. The biological shielding consists of an ordinary concrete wall 30 cm thick; the dose rate is thus limited at 10 -1 mrem per discharge (corresponding to 10 mrem per day) in the whole area frequented by people during T.F.R. operation. A numerical calculation, taking into account the true geometry and X ray reflexion by the walls and roof, and normalized to the measurements, gives some indications on the electron beam which produces X rays. The photoneutron source (up to 10 10 neutrons per dischage) and the activation of the vacuum vessel result from high energy electrons (>= 10 MeV) supporting a 10 to 1,000 A current [fr

  8. Study on kinematic and compliance test of suspension

    Science.gov (United States)

    Jing, Lixin; Wu, Liguang; Li, Xuepeng; Zhang, Yu

    2017-09-01

    Chassis performance development is a major difficulty in vehicle research and development, which is the main factor restricting the independent development of vehicles in China. These years, through a large number of studies, chassis engineers have found that the suspension K&C characteristics as a quasi-static characteristic of the suspension provides a technical route for the suspension performance R&D, and the suspension K&C test has become an important means of vehicle benchmarking, optimization and verification. However, the research on suspension K&C test is less in china, and the test conditions and setting requirements vary greatly from OEM to OEM. In this paper, the influence of different settings on the characteristics of the suspension is obtained through experiments, and the causes of the differences are analyzed; in order to fully reflect the suspension characteristics, the author recommends the appropriate test case and settings.

  9. Rate Processes in Dissipative Systems: 50 Years After Kramers, Discussion Meeting Held in Tutzing (Germany, F.R.) on 10-13 September 1990

    Science.gov (United States)

    1990-09-13

    Chem. Soc., Faraday Trans. [5] S. T. Abdel-Halim, M. H. Abdel-Kader, and U. E. Steiner , J. 2, 83, 1941 (1987), Phys. Chem 92, 4324 (1988). [29] W...December 5th, 1990) Zusammensetzung, Eigenschaften und Anwendungen Mesomorpher Tensidphasen RUDOLF HEUSCH Leverkusen, Paul-Klee-StraBe 85 (Received on...Institut f~r Anorganisehe Chemnie der Universitiit Rudower Chaussee 5, 0-1199 Physikalisehe Chemie) Rudolf - Bern, Freie Stra~e 3, CH-3000 Bern, be- Berlin

  10. Methodology of Education and R&D in Mechatronics.

    Science.gov (United States)

    Yamazaki, K.; And Others

    1985-01-01

    Describes the concept and methodology of "mechatronics" (application of microelectronics to mechanism control) and research and development (R&D) projects through the activities initiated at the Precision Machining Laboratory of the Department of Production Systems Engineering of the new Toyohashi University of Technology. (JN)

  11. Behaviour of humic-bentonite aggregates in diluted suspensions ...

    African Journals Online (AJOL)

    Formation and disaggregation of micron-size aggregates in a diluted suspension made up of HSs and bentonite (B) were studied by tracing distribution of aggregate sizes and their counts in freshly prepared and aged suspensions, and at high (10 000) and low (1.0) [HS]/[B] ratios. Diluted HSB suspensions are unstable ...

  12. 75 FR 81031 - Consideration of Environmental Impacts of Temporary Storage of Spent Fuel After Cessation of...

    Science.gov (United States)

    2010-12-23

    ... ignore intergenerational ethical concerns of this generation reaping the benefits of nuclear energy while... Part VI Nuclear Regulatory Commission 10 CFR Part 51 Consideration of Environmental Impacts of... Consideration of Environmental Impacts of Temporary Storage of Spent Fuel After Cessation of Reactor Operation...

  13. Coagulation of highly turbid suspensions using magnesium hydroxide: effects of slow mixing conditions.

    Science.gov (United States)

    Ayoub, George M; BinAhmed, Sara W; Al-Hindi, Mahmoud; Azizi, Fouad

    2014-09-01

    Laboratory experiments were carried out to study the effects of slow mixing conditions on magnesium hydroxide floc size and strength and to determine the turbidity and total suspended solid (TSS) removal efficiencies during coagulation of highly turbid suspensions. A highly turbid kaolin clay suspension (1,213 ± 36 nephelometric turbidity units (NTU)) was alkalized to pH 10.5 using a 5 M NaOH solution; liquid bittern (LB) equivalent to 536 mg/L of Mg(2+) was added as a coagulant, and the suspension was then subjected to previously optimized fast mixing conditions of 100 rpm and 60 s. Slow mixing speed (20, 30, 40, and 50 rpm) and time (10, 20, and 30 min) were then varied, while the temperature was maintained at 20.7 ± 1 °C. The standard practice for coagulation-flocculation jar test ASTM D2035-13 (2013) was followed in all experiments. Relative floc size was monitored using an optical measuring device, photometric dispersion analyzer (PDA 2000). Larger and more shear resistant flocs were obtained at 20 rpm for both 20- and 30-min slow mixing times; however, given the shorter duration for the former, the 20-min slow mixing time was considered to be more energy efficient. For slow mixing camp number (Gt) values in the range of 8,400-90,000, it was found that the mixing speed affected floc size and strength more than the time. Higher-turbidity removal efficiencies were achieved at 20 and 30 rpm, while TSS removal efficiency was higher for the 50-rpm slow mixing speed. Extended slow mixing time of 30 min yielded better turbidity and TSS removal efficiencies at the slower speeds.

  14. Simulation 󈨔 Symposium.

    Science.gov (United States)

    1980-11-21

    Chemical Process 8:10 - 8:30 p.m. F.J. Pasveer / J.N. van der Molen / J.J. de Kramer (The Netherlands) Diffusion Flow through Irregular Dhaped Pores 8:30...Cycloconverter Including Control and Firing Devices 11:30 - 11:50 a.m. G. Lekkas (Switzerland) Simulation einer Stromrichterlokomotive zur Bestimmung der ...Schreiber / A. Schr~ der (FRG) Modeling and Simulation of Urban Sewer Systems(Double length key paper) 2:40 3:00 p.m. R. Laurent / M. Barboucha (France

  15. Temporary Fecal Diversion in the Management of Colorectal and Perianal Crohn’s Disease

    Directory of Open Access Journals (Sweden)

    Rudolf Mennigen

    2015-01-01

    Full Text Available Aim. To evaluate the results of temporary fecal diversion in colorectal and perianal Crohn’s disease. Method. We retrospectively identified 29 consecutive patients (14 females, 15 males; median age: 30.0 years, range: 18–76 undergoing temporary fecal diversion for colorectal (n=14, ileal (n=4, and/or perianal Crohn’s disease (n=22. Follow-up was in median 33.0 (3–103 months. Response to fecal diversion, rate of stoma reversal, and relapse rate after stoma reversal were recorded. Results. The response to temporary fecal diversion was complete remission in 4/29 (13.8%, partial remission in 12/29 (41.4%, no change in 7/29 (24.1%, and progress in 6/29 (20.7%. Stoma reversal was performed in 19 out of 25 patients (76% available for follow-up. Of these, the majority (15/19, 78.9% needed further surgical therapies for a relapse of the same pathology previously leading to temporary fecal diversion, including colorectal resections (10/19, 52.6% and creation of a definitive stoma (7/19, 36.8%. At the end of follow-up, only 4/25 patients (16% had a stable course without the need for further definitive surgery. Conclusion. Temporary fecal diversion can induce remission in otherwise refractory colorectal or perianal Crohn’s disease, but the chance of enduring remission after stoma reversal is low.

  16. 78 FR 29200 - Benda Pharmaceutical, Inc. and China Shuangjii Cement Ltd., Order of Suspension of Trading

    Science.gov (United States)

    2013-05-17

    ... SECURITIES AND EXCHANGE COMMISSION [File No. 500-1] Benda Pharmaceutical, Inc. and China Shuangjii Cement Ltd., Order of Suspension of Trading May 15, 2013. It appears to the Securities and Exchange... Pharmaceutical, Inc. because it has not filed any periodic reports since the period ended September 30, 2010. It...

  17. 77 FR 76854 - Temporary Rule Regarding Principal Trades With Certain Advisory Clients

    Science.gov (United States)

    2012-12-31

    ... 3235-AL28 Temporary Rule Regarding Principal Trades With Certain Advisory Clients AGENCY: Securities... transactions with certain of their advisory clients. The amendment extends the date on which rule 206(3)- 3T... releases used RIN 3235-AJ96. (See Temporary Rule Regarding Principal Trades with Certain Advisory Clients...

  18. 49 CFR 393.207 - Suspension systems.

    Science.gov (United States)

    2010-10-01

    ... braking system. The vehicle shall be level (not tilting to the left or right). Air leakage shall not be... 49 Transportation 5 2010-10-01 2010-10-01 false Suspension systems. 393.207 Section 393.207... NECESSARY FOR SAFE OPERATION Frames, Cab and Body Components, Wheels, Steering, and Suspension Systems § 393...

  19. 46 CFR 194.10-30 - Magazine sprinklers.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Magazine sprinklers. 194.10-30 Section 194.10-30..., USE, AND CONTROL OF EXPLOSIVES AND OTHER HAZARDOUS MATERIALS Magazines § 194.10-30 Magazine sprinklers... shall be installed in each magazine or magazine group. The control valve shall generally be in...

  20. 46 CFR 59.10-30 - Seal welding.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 2 2010-10-01 2010-10-01 false Seal welding. 59.10-30 Section 59.10-30 Shipping COAST... VESSELS AND APPURTENANCES Welding Repairs to Boilers and Pressure Vessels in -Service § 59.10-30 Seal welding. Where leaks occur in riveted joints or connections, they shall be carefully investigated to...

  1. 77 FR 63725 - Drawbridge Operation Regulations; Old River, Orwood, CA

    Science.gov (United States)

    2012-10-17

    ... BNSF Middle River drawbridge as an alternative path for navigation. DATES: The temporary deviation... Operation Regulation; Old River, Orwood CA'' in the Federal Register (77 FR 58491). The temporary deviation... Operation Regulations; Old River, Orwood, CA AGENCY: Coast Guard, DHS. ACTION: Notice of cancellation of a...

  2. 46 CFR 61.30-10 - Hydrostatic test.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 2 2010-10-01 2010-10-01 false Hydrostatic test. 61.30-10 Section 61.30-10 Shipping... INSPECTIONS Tests and Inspections of Fired Thermal Fluid Heaters § 61.30-10 Hydrostatic test. All new installations of thermal fluid heaters must be given a hydrostatic test of 11/2 times the maximum allowable...

  3. A comparison of the temporary placement of 3 different self-expanding stents for the treatment of refractory benign esophageal strictures: a prospective multicentre study

    Directory of Open Access Journals (Sweden)

    Canena Jorge Manuel

    2012-06-01

    Full Text Available Abstract Background Refractory benign esophageal strictures (RBESs have been treated with the temporary placement of different self-expanding stents with conflicting results. We compared the clinical effectiveness of 3 types of stents: self-expanding plastic stents (SEPSs, biodegradable stents, and fully covered self-expanding metal stents (FCSEMSs, for the treatment of RBES. Methods This study prospectively evaluated 3 groups of 30 consecutive patients with RBESs who underwent temporary placement of either SEPSs (12 weeks, n = 10, biodegradable stents (n = 10 or FCSEMSs (12 weeks, n = 10. Data were collected to analyze the technical success and clinical outcome of the stents as evaluated by recurrent dysphagia, complications and reinterventions. Results Stent implantation was technically successful in all patients. Migration occurred in 11 patients: 6 (60% in the SEPS group, 2 (20% in the biodegradable group and 3 (30% in the FCSEMS group (P = 0.16. A total of 8/30 patients (26.6% were dysphagia-free after the end of follow-up: 1 (10% in the SEPS group, 3 (30% in the biodegradable group and 4 (40% in the FCSEMS group (P = 0.27. More reinterventions were required in the SEPS group (n = 24 than in the biodegradable group (n = 13 or the FCSEMS group (n = 13 (P = 0.24. Multivariate analysis showed that stricture length was significantly associated with higher recurrence rates after temporary stent placement (HR = 1.37; 95% CI = 1.08-1.75; P = 0.011. Conclusions Temporary placement of a biodegradable stent or of a FCSEMS in patients with RBES may lead to long-term relief of dysphagia in 30 and 40% of patients, respectively. The use of SEPSs seems least preferable, as they are associated with frequent stent migration, more reinterventions and few cases of long-term improvement. Additionally, longer strictures were associated with a higher risk of recurrence.

  4. 77 FR 63835 - Office of the Chief Information Officer; Submission for OMB Review; Temporary Contractor...

    Science.gov (United States)

    2012-10-17

    ... of the Chief Information Officer; Submission for OMB Review; Temporary Contractor Information... information collection requirement regarding temporary contractor information worksheet. A notice was... for temporary contractors as a result of the American Recovery and Reinvestment Act of 2009 (Public...

  5. 10 CFR 712.30 - Applicability.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 4 2010-01-01 2010-01-01 false Applicability. 712.30 Section 712.30 Energy DEPARTMENT OF ENERGY HUMAN RELIABILITY PROGRAM Medical Standards § 712.30 Applicability. This subpart establishes standards and procedures for conducting medical assessments of DOE and DOE contractor individuals in HRP...

  6. Versatility of {l_brace}M(30-crown-10){r_brace} (M = K{sup +}, Ba{sup 2+}) as a guest in UO{sub 2}{sup 2+} complexes of 3.1.3.1 - and 3.3.3 homo-oxa-calixarenes

    Energy Technology Data Exchange (ETDEWEB)

    Masci, B. [Univ Roma La Sapienza, Dipartimento Chim, I-00185 Rome, (Italy); Thuery, P. [CEA Saclay, DSM/DRECAM/SCM, CNRS-URA 331, F-91191 Gif Sur Yvette, (France)

    2007-07-01

    The reaction between p-R-[3.1.3.1]- or [3.3.3] homo-oxa-calixarenes and uranyl salts in the presence of 30-crown-10 and the alkali or alkaline-earth metal cations K{sup +} or Ba{sup 2+} gives various supramolecular assemblages characterized by 'complex-within-complex' architectures. These can be of the simple nesting or sandwich types, as in [{l_brace}Ba(30-crown-10){r_brace}{l_brace}UO{sub 2}(L{sup 1}){r_brace}]. 2H{sub 2}O.3CHCl{sub 3} (L{sup 1}H{sub 4} p-tert-butyl[3.1.3.1] homo-oxa-calixarene) and [{l_brace}Ba(30-crown-10){r_brace}{l_brace}UO{sub 2}(L{sup 4}){r_brace}{sub 2}].2CHCl{sub 3} (L{sup 4}H{sub 3} p-bromo[3.3.3]homo-oxa-calixarene), respectively, with the cation held in the cavity of the homo-oxa-calixarene complexes in cone conformation by weak interactions, but more original structures arise when uranyl-cation bonds are present. In [{l_brace}Ba(30-crown-10){r_brace}{l_brace}UO{sub 2}(L{sup 2}){r_brace}] (L{sup 2}H{sub 4} p-phenyl[3.1.3.1] homo-oxa-calixarene), the barium ion included in the crown ether is bound to the uranyl oxo group located out of the calixarene cavity, resulting in the formation of a neutral species which self-organizes to form a columnar assembly by auto-inclusion. In [{l_brace}K(30-crown-10){r_brace}{l_brace}UO{sub 2}K(L{sup 1})(H{sub 2}O){sub 3}{r_brace}]{sub 2}.6H{sub 2}O, the nesting-type subunit dimerizes around two oxo-bound potassium ions. Finally, the use of the coordinating solvent dimethylsulfoxide leads to the neutral complex [UO{sub 2}Ba(L{sup 3})(dmso){sub 2}(MeOH)]{sub 2} (L{sup 3}H{sub 4} = p-methyl[3.1.3.1] homo-oxa-calixarene), in which the crown ether is absent and two oxo-, phenoxo- and ether-bound barium atoms ensure the dimerization of the uranyl complex. (authors)

  7. Monte Carlo determinations of the functions Λ(r, Z), G(r, θ), g(R) and F(r, θ) for Amersham CDCS-M-type 137Cs source

    International Nuclear Information System (INIS)

    Valdez, F. Roberto Fragoso; Alvarez Romero, J. Trinidad

    2001-01-01

    The functions Λ(r, z), G(r, θ), g(r) and F(r, θ) were calculated for Amersham model CDCS-M-type 137 Cs source by means of Monte Carlo simulation using the algorithm PENELOPE. These functions are required to verify and/or to feed planning systems or directly as entrance data for the manual planning of the distribution of absorbed dose according with the recommendations of the TG 43, [1]. The values of the constant Λ (r, Z) were determined as the quotient of absorbed dose rate distribution in water and air kerma strength in 'free air' S k . The values obtained for Λ (r, Z) differ up to 3% of those reported in the literature, being very sensitive to the cutoff energy for the electrons in the interface of the source's encapsulated and water

  8. Temporary diplopia upon hyoscine-N-butyl bromide administration: case report

    Directory of Open Access Journals (Sweden)

    Migliorini R

    2013-05-01

    Full Text Available R Migliorini, R Malagola, M Mafrici, R Spena, L ArricoDepartment of Sense Organs, University of Rome "La Sapienza", Rome, ItalyAbstract: Hyoscine-N-butyl bromide is a widely used antispasmodic belonging to the belladonna alkaloid class of semisynthetic quaternary ammonium compounds. These compounds exert a spasmolytic action on the smooth muscles of the bile-gastrointestinal tract, genitourinary tract, salivary glands (xerostomia, and also on the visual apparatus – in particular, the irido-ciliary complex. As a consequence, they provoke collateral effects such as mydriasis and accommodation disturbances. We report the case of a 23-year-old woman who complained of not only "dry mouth" but also "cloudy vision" and a "diplopia", both of temporary type, 2 hours after oral administration of hyoscine-N-butyl bromide.Keywords: hyoscine-N-butyl bromide, accommodation disorders, temporary diplopia, fusion alteration, vertical strabismus

  9. Effect of different vehicles in carrageenan suspension on the rate of the inflammatory response of chicks

    Directory of Open Access Journals (Sweden)

    Alda Maria Backx Noronha Madeira

    1995-12-01

    Full Text Available This paper describes the pattern of edema, increased vascular permeability and cellular exudation elicited by the injection of different carrageenan suspensions into the foot pad of 80 male chicks, three to four-week old. Carrageenan suspensions at 0.5% were prepared in: Ringer Locke solution (RL, glucose aqueous solution 0.1% (G, demineralized water (W or phosphate buffered saline (PBS. The foot pad volume and vascular permeability were evaluated by pletismography and by Evans blue extravasation, respectively, before and at 0:15, 0:30, 1:00, 1:30, 2:00, 2:30, 3:00, 3:30 and 4:00 hours after injury. Cellular exudation was observed in thin sections of stained tissue 0:30, 1:30, 2:30 and 4:00 hours after injection of the carrageenan or vehicle only. The inflammatory response varied according to the carrageenan suspension used. Suspension C/PBS induced a less intense inflammatory response in foot pads of chicks than C/W, C/G and C/RL suspensions.

  10. Return to Work After Temporary Disability Pension in Finland.

    Science.gov (United States)

    Laaksonen, Mikko; Gould, Raija

    2015-09-01

    When it is possible that the employee's work ability can be restored through treatment or rehabilitation, disability pension in Finland is granted for a fixed period. We examined which factors are associated with return to work (RTW) after such temporary disability pension. The study included all Finnish residents whose temporary disability pension from the earnings-related pension system started in 2008 (N = 10,269). Competing risks regression analysis was applied to examine register-based determinants for RTW after temporary disability pension due to mental disorders, musculoskeletal diseases, other diseases, and injury over a 4-year follow-up period. The overall cumulative incidence of RTW was 25%. RTW was more probable after temporary disability pension due to injury and musculoskeletal diseases and less probable after temporary disability pension due to mental disorders. Younger age and higher education increased RTW but differences between genders, private and public sector employees, and occupational classes were relatively small. The probability of RTW was higher among those who were employed before their temporary disability pension (subhazard ratio in multivariate analysis 2.41 (95% CI 2.13-2.72) and among the 9% who participated in vocational rehabilitation during their pension [SHR 2.10 (95% CI 1.90-2.31)]. With some exceptions, the results were fairly similar for all diagnostic causes of temporary disability pension. Return to work after temporary disability pension was relatively uncommon. Nevertheless, in all diagnostic groups RTW continued for the whole follow-up period. The low educated and those not employed before temporary disability pension need more support in their RTW. The strong association between vocational rehabilitation and RTW suggests that increasing rehabilitation among those with impaired work ability may promote RTW.

  11. Study of conditions of production and characterization of noble metal micro-particles suspensions

    International Nuclear Information System (INIS)

    Malabre, Catherine

    1983-01-01

    As the production and identification of metal micro-particle suspensions are some aspects of issues related to nuclear fuel reprocessing, this research thesis reports the use of ruthenium, molybdenum, niobium, palladium and rhodium (fission metals) to generate such micro-particles. They are produced by erosion of two electrodes between which occurs an electric arc discharge in aqueous media. Different analytic methods are developed to determine the characteristics of so-produced colloidal solutions. A granulometry study is performed by transmission electronic microscopy, light quasi-elastic scattering, and turbidimetry associated to centrifugation. This has lead to the production of steady micro-particle suspensions which have been used in a first set of industrial trials [fr

  12. 78 FR 15402 - Xytos, Inc.; Order of Suspension of Trading

    Science.gov (United States)

    2013-03-11

    ... SECURITIES AND EXCHANGE COMMISSION [ File No. 500-1] Xytos, Inc.; Order of Suspension of Trading... financial conditions and business operations, and because of potentially manipulative conduct in the trading... investors require a suspension of trading in the securities of the above-listed company. Therefore, it is...

  13. Nonlinear evolution of f(R) cosmologies. II. Power spectrum

    International Nuclear Information System (INIS)

    Oyaizu, Hiroaki; Hu, Wayne; Lima, Marcos

    2008-01-01

    We carry out a suite of cosmological simulations of modified action f(R) models where cosmic acceleration arises from an alteration of gravity instead of dark energy. These models introduce an extra scalar degree of freedom which enhances the force of gravity below the inverse mass or Compton scale of the scalar. The simulations exhibit the so-called chameleon mechanism, necessary for satisfying local constraints on gravity, where this scale depends on environment, in particular, the depth of the local gravitational potential. We find that the chameleon mechanism can substantially suppress the enhancement of power spectrum in the nonlinear regime if the background field value is comparable to or smaller than the depth of the gravitational potentials of typical structures. Nonetheless power spectrum enhancements at intermediate scales remain at a measurable level for models even when the expansion history is indistinguishable from a cosmological constant, cold dark matter model. Simple scaling relations that take the linear power spectrum into a nonlinear spectrum fail to capture the modifications of f(R) due to the change in collapsed structures, the chameleon mechanism, and the time evolution of the modifications.

  14. Spherically Symmetric Geometries in f(T) and f(R) Gravitational Theories

    International Nuclear Information System (INIS)

    Nashed, Gamal G. L.

    2015-01-01

    Using the well know relation between Ricci scalar, R, and torsion scalar, T, that is, R=-T-2∇_αT"α, we show that, for any spherically symmetric spacetime whose (i) scalar torsion vanishing, that is, T=T_μ_ν"αS_α"μ"ν=0 or (ii) total derivative term, that is, ∇_αT"α with T"α is the contraction of the torsion, vanishing, or (iii) the combination of scalar torsion and total derivative term vanishing, could be solution for f(T) and f(R) gravitational theories.

  15. 48 CFR 30.202-5 - Filing disclosure statements.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Filing disclosure... GENERAL CONTRACTING REQUIREMENTS COST ACCOUNTING STANDARDS ADMINISTRATION CAS Program Requirements 30.202-5 Filing disclosure statements. See 48 CFR 9903.202-5 (FAR appendix). [61 FR 18917, Apr. 29, 1996...

  16. 78 FR 27992 - Notice of Temporary Closures of Public Land in Washoe County, NV

    Science.gov (United States)

    2013-05-13

    .... Leon Thomas, Field Manager, Sierra Front Field Office. [FR Doc. 2013-11284 Filed 5-10-13; 8:45 am... City District Office will temporarily close certain public land near Stead, Nevada, to all public use... call the Federal Information Relay Service (FIRS) at 1- 800-877-8339 to contact the above individual...

  17. Laryngeal Force Sensor: Quantifying Extralaryngeal Complications after Suspension Microlaryngoscopy.

    Science.gov (United States)

    Feng, Allen L; Song, Phillip C

    2018-04-01

    Objectives To develop a novel sensor capable of dynamically analyzing the force exerted during suspension microlaryngoscopy and to examine the relationship between force and postoperative tongue complications. Study Design Prospective observational study. Setting Academic tertiary care center. Methods The laryngeal force sensor is a designed for use during microphonosurgery. Prospectively enrolled patients completed pre- and postoperative surveys to assess the development of tongue-related symptoms (dysgeusia, pain, paresthesia, and paresis) or dysphagia (10-item Eating Assessment Tool [EAT-10]). To prevent operator bias, surgeons were blinded to the force recordings during surgery. Results Fifty-six patients completed the study. Of these, 20 (36%) developed postoperative tongue symptoms, and 12 (21%) had abnormal EAT-10 scores. The mean maximum force across all procedures was 164.7 N (95% CI, 141.0-188.4; range, 48.5-402.6), while the mean suspension time was 34.3 minutes (95% CI, 27.4-41.2; range, 7.1-108.1). Multiple logistic regression showed maximum force (odds ratio, 1.15; 95% CI, 1.02-1.29; P = .019) and female sex (30.1%; 95% CI, 22.7%-37.5%; P force (odds ratio, 1.03; 95% CI, 1.00-1.06; P = .045). Conclusions The laryngeal force sensor is capable of providing dynamic force measurements throughout suspension microlaryngoscopy. An increase in maximum force during surgery may be a significant predictor for the development of tongue-related symptoms and an abnormal EAT-10 score. Female patients may also be at greater risk for developing postoperative tongue symptoms.

  18. An Assessment of the Seismicity of the Bursa Region from a Temporary Seismic Network

    Science.gov (United States)

    Gok, Elcin; Polat, Orhan

    2012-04-01

    A temporary earthquake station network of 11 seismological recorders was operated in the Bursa region, south of the Marmara Sea in the northwest of Turkey, which is located at the southern strand of the North Anatolian Fault Zone (NAFZ). We located 384 earthquakes out of a total of 582 recorded events that span the study area between 28.50-30.00°E longitudes and 39.75-40.75°N latitudes. The depth of most events was found to be less than 29 km, and the magnitude interval ranges were between 0.3 ≤ ML ≤ 5.4, with RMS less than or equal to 0.2. Seismic activities were concentrated southeast of Uludag Mountain (UM), in the Kestel-Igdir area and along the Gemlik Fault (GF). In the study, we computed 10 focal mechanisms from temporary and permanents networks. The predominant feature of the computed focal mechanisms is the relatively widespread near horizontal northwest-southeast (NW-SE) T-axis orientation. These fault planes have been used to obtain the orientation and shape factor (R, magnitude stress ratio) of the principal stress tensors (σ1, σ2, σ3). The resulting stress tensors reveal σ1 closer to the vertical (oriented NE-SW) and σ2, σ3 horizontal with R = 0.5. These results confirm that Bursa and its vicinity could be defined by an extensional regime showing a primarily normal to oblique-slip motion character. It differs from what might be expected from the stress tensor inversion for the NAFZ. Different fault patterns related to structural heterogeneity from the north to the south in the study area caused a change in the stress regime from strike-slip to normal faulting.

  19. Generic f(R) theories and classicality of their scalarons

    Energy Technology Data Exchange (ETDEWEB)

    Gannouji, Radouane [Department of Physics, Faculty of Science, Tokyo University of Science, 1-3, Kagurazaka, Shinjuku-ku, Tokyo 162-8601 (Japan); Sami, M., E-mail: samijamia@gmail.com [Kobayashi-Maskawa Institute for the Origin of Particles and the Universe, Nagoya University, Nagoya 464-8602 (Japan); Thongkool, I. [Harish-Chandra Research Institute, Chhatnag Road, Jhusi, Allahabad-211019 (India)

    2012-09-19

    We study quantum stability bound on the mass of scalaron in generic theories of f(R) gravity. We show that in these scenarios, the scalaron mass increases faster with local density of the environment than one-loop quantum correction to it thereby leading to violation of quantum bound on the chameleon mass. The introduction of quadratic curvature corrections in the action are shown to stabilize the model.

  20. 75 FR 68636 - 8000, Inc.; Order of Suspension of Trading

    Science.gov (United States)

    2010-11-08

    ... SECURITIES AND EXCHANGE COMMISSION [File No. 500-1] 8000, Inc.; Order of Suspension of Trading... and the protection of investors require a suspension of trading in the securities of 8000, Inc. Therefore, it is ordered, pursuant to Section 12(k) of the Securities Exchange Act of 1934, that trading in...

  1. Using Noether symmetries to specify f(R) gravity

    International Nuclear Information System (INIS)

    Paliathanasis, Andronikos

    2013-01-01

    A detailed study of the modified gravity, f(R) models is performed, using the fact that the Noether point symmetries of these models are geometric symmetries of the mini su-perspace of the theory. It is shown that the requirement that the field equations admit Noether point symmetries selects definite models in a self-consistent way. As an application in Cosmology we consider the Friedman -Robertson-Walker spacetime and show that the only cosmological model which is integrable via Noether point symmetries is the (R b − 2Λ) c model, which generalizes the Lambda Cosmology. Furthermore using the corresponding Noether integrals we compute the analytic form of the main cosmological functions

  2. 75 FR 53985 - Arizona Public Service Company, et al., Palo Verde Nuclear Generating Station, Unit 3; Temporary...

    Science.gov (United States)

    2010-09-02

    ... NUCLEAR REGULATORY COMMISSION [Docket No. STN 50-530; NRC-2010-0281] Arizona Public Service Company, et al., Palo Verde Nuclear Generating Station, Unit 3; Temporary Exemption 1.0 Background Arizona Public Service Company (APS, the licensee) is the holder of Facility Operating License No. NPF-74, which...

  3. 45 CFR 99.4 - Suspension of rules.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 1 2010-10-01 2010-10-01 false Suspension of rules. 99.4 Section 99.4 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION PROCEDURE FOR HEARINGS FOR THE CHILD CARE AND DEVELOPMENT FUND General § 99.4 Suspension of rules. With notice to all parties, the...

  4. 78 FR 76377 - Makism3D Corp.; Order of Suspension of Trading

    Science.gov (United States)

    2013-12-17

    ... SECURITIES AND EXCHANGE COMMISSION [File No. 500-1] Makism3D Corp.; Order of Suspension of Trading... protection of investors require a suspension of trading in the securities of Makism3D Corp. (``Makism3D... opinion that the public interest and the protection of investors require a suspension of trading in the...

  5. Novel star-like surfactant as dispersant for multi-walled carbon nanotubes in aqueous suspensions at high concentration

    Science.gov (United States)

    Qiao, Min; Ran, Qianping; Wu, Shishan

    2018-03-01

    A kind of novel surfactant with star-like molecular structure and terminated sulfonate was synthesized, and it was used as the dispersant for multi-walled carbon nanotubes (CNTs) in aqueous suspensions compared with a traditional single-chained surfactant. The star-like surfactant showed good dispersing ability for multi-walled CNTs in aqueous suspensions. Surface tension analysis, total organic carbon analysis, X-ray photoelectron spectroscopy, zeta potential, dynamic light scattering and transmission electron microscopy were performed to research the effect of star-like surfactant on the dispersion of multi-walled CNTs in aqueous suspensions. With the assistance of star-like surfactant, the CNTs could disperse well in aqueous suspension at high concentration of 50 g/L for more than 30 days, while the CNTs precipitated completely in aqueous suspension after 1 day without any dispersant or after 10 days with sodium 4-dodecylbenzenesulfonic acid as dispersant.

  6. miR-10 in development and cancer

    DEFF Research Database (Denmark)

    Lund, Anders Henrik

    2010-01-01

    The microRNA (miRNA) miR-10 family has attracted attention because of its conservation and the position of the miR-10 genes within the Hox clusters of developmental regulators. In several species, miR-10 is coexpressed with a set of Hox genes and has been found to regulate the translation of Hox ...... function to the miRNA repertoire.Cell Death and Differentiation advance online publication, 22 May 2009; doi:10.1038/cdd.2009.58....

  7. 78 FR 20123 - Extension of the Designation of Honduras for Temporary Protected Status

    Science.gov (United States)

    2013-04-03

    ... Docket No. USCIS-2012-0016] RIN 1615-ZB18 Extension of the Designation of Honduras for Temporary... the designation of Honduras for Temporary Protected Status (TPS) for 18 months from July 6, 2013... Honduras that prompted the TPS designation continue to be met. There continues to be a substantial, but...

  8. Thick brane in f(R) gravity with Palatini dynamics

    International Nuclear Information System (INIS)

    Bazeia, D.; Losano, L.; Menezes, R.; Olmo, Gonzalo J.; Rubiera-Garcia, D.

    2015-01-01

    This work deals with modified gravity in five-dimensional space-time. We study a thick Palatini f(R) brane, that is, a braneworld scenario described by an anti-de Sitter warped geometry with a single extra dimension of infinite extent, sourced by a real scalar field under the Palatini approach, where the metric and the connection are regarded as independent degrees of freedom. We consider a first-order framework which we use to provide exact solutions for the scalar field and warp factor. We also investigate a perturbative scenario such that the Palatini approach is implemented through a Lagrangian f(R)=R+ϵR n , where the small parameter ϵ controls the deviation from the standard thick brane case. In both cases it is found that the warp factor tends to localize the extra dimension due to the nonlinear corrections

  9. Thick brane in f(R) gravity with Palatini dynamics

    Energy Technology Data Exchange (ETDEWEB)

    Bazeia, D., E-mail: bazeia@fisica.ufpb.br; Losano, L., E-mail: losano@fisica.ufpb.br [Departamento de Física, Universidade Federal da Paraíba, 58051-900, João Pessoa, PB (Brazil); Menezes, R., E-mail: rmenezes@dce.ufpb.br [Departamento de Ciências Exatas, Universidade Federal da Paraíba, 58297-000, Rio Tinto, PB (Brazil); Departamento de Física, Universidade Federal de Campina Grande, 58109-970, Campina Grande, PB (Brazil); Olmo, Gonzalo J., E-mail: gonzalo.olmo@csic.es [Departamento de Física, Universidade Federal da Paraíba, 58051-900, João Pessoa, PB (Brazil); Departamento de Física Teórica, IFIC, Centro Mixto Universidad de Valencia-CSIC, Universidad de Valencia, 46100, Burjassot, Valencia (Spain); Rubiera-Garcia, D., E-mail: drgarcia@fc.ul.pt [Departamento de Física, Universidade Federal da Paraíba, 58051-900, João Pessoa, PB (Brazil); Faculdade de Ciências, Instituto de Astrofísica e Ciências do Espaço, Universidade de Lisboa, Campo Grande, 1749-016, Lisbon (Portugal); Department of Physics, Center for Field Theory and Particle Physics, Fudan University, 220 Handan Road, 200433, Shanghai (China)

    2015-11-30

    This work deals with modified gravity in five-dimensional space-time. We study a thick Palatini f(R) brane, that is, a braneworld scenario described by an anti-de Sitter warped geometry with a single extra dimension of infinite extent, sourced by a real scalar field under the Palatini approach, where the metric and the connection are regarded as independent degrees of freedom. We consider a first-order framework which we use to provide exact solutions for the scalar field and warp factor. We also investigate a perturbative scenario such that the Palatini approach is implemented through a Lagrangian f(R)=R+ϵR{sup n}, where the small parameter ϵ controls the deviation from the standard thick brane case. In both cases it is found that the warp factor tends to localize the extra dimension due to the nonlinear corrections.

  10. 30 år med Musikterapi. Oplevelser, Erfaringer, Visioner

    DEFF Research Database (Denmark)

    2012-01-01

    I anledning af musikterapiuddannelsens 30 års jubilæum har vi opsøgt og interviewet relevante samarbejdspartnere for at få et indblik i, hvordan de opfatter musikterapien. Efter 30 år, hvor vi konstant har arbejdet på at forbedre musikterapiuddannelsen, synes vi nemlig, at det er spændende at und...

  11. 78 FR 46339 - Medicare, Medicaid, and Children's Health Insurance Programs: Announcement of Temporary Moratoria...

    Science.gov (United States)

    2013-07-31

    ...] Medicare, Medicaid, and Children's Health Insurance Programs: Announcement of Temporary Moratoria on... combat fraud, waste, and abuse in Medicare, Medicaid, and the Children's Health Insurance Program (CHIP... Health Insurance Programs; Additional Screening Requirements, Application Fees, Temporary Enrollment...

  12. 75 FR 68704 - Suspension of Community Eligibility

    Science.gov (United States)

    2010-11-09

    ... DEPARTMENT OF HOMELAND SECURITY Federal Emergency Management Agency 44 CFR Part 64 [Docket ID FEMA-2010-0003; Internal Agency Docket No. FEMA-8155] Suspension of Community Eligibility AGENCY: Federal.... Acadia Parish. Emerg; February 4, 1981, Reg; November 26, 2010, Susp. Iota, Town of, Acadia 220005...

  13. Variation in hepatitis B immunization coverage rates associated with provider practices after the temporary suspension of the birth dose

    Directory of Open Access Journals (Sweden)

    Mullooly John P

    2006-11-01

    Full Text Available Abstract Background In 1999, the American Academy of Pediatrics and U.S. Public Health Service recommended suspending the birth dose of hepatitis B vaccine due to concerns about potential mercury exposure. A previous report found that overall national hepatitis B vaccination coverage rates decreased in association with the suspension. It is unknown whether this underimmunization occurred uniformly or was associated with how providers changed their practices for the timing of hepatitis B vaccine doses. We evaluate the impact of the birth dose suspension on underimmunization for the hepatitis B vaccine series among 24-month-olds in five large provider groups and describe provider practices potentially associated with underimmunization following the suspension. Methods Retrospective cohort study of children enrolled in five large provider groups in the United States (A-E. Logistic regression was used to evaluate the association between the birth dose suspension and a child's probability of being underimmunized at 24 months for the hepatitis B vaccine series. Results Prior to July 1999, the percent of children who received a hepatitis B vaccination at birth varied widely (3% to 90% across the five provider groups. After the national recommendation to suspend the hepatitis B birth dose, the percent of children who received a hepatitis B vaccination at birth decreased in all provider groups, and this trend persisted after the policy was reversed. The most substantial decreases were observed in the two provider groups that shifted the first hepatitis B dose from birth to 5–6 months of age. Accounting for temporal trend, children in these two provider groups were significantly more likely to be underimmunized for the hepatitis B series at 24 months of age if they were in the birth dose suspension cohort compared with baseline (Group D OR 2.7, 95% CI 1.7 – 4.4; Group E OR 3.1, 95% CI 2.3 – 4.2. This represented 6% more children in Group D and 9

  14. Intraperitoneal distribution of 32P-chromic phosphate suspension in the dog

    International Nuclear Information System (INIS)

    Tewfik, H.H.; Gruber, H.; Tewfik, F.A.; Lifshitz, S.G.

    1979-01-01

    Intraperitoneal administration of radioactive chromic phosphate suspension is receiving renewed attention as a therapeutic treatment to limit metastatic dissemination of ovarian carcinoma. Our study utilized mongrel dogs to approximate the uptake and distribution of 3.0 millicuries 32 P-chromic phosphate suspension administered intraperitoneally (IP). Lymph nodes, omentum, retroperitoneum, peritoneum, diaphragm, abdominal wall muscle, pleura, spleen, liver, kidneys, lung, small intestine, and blood were sampled for liquid scintillation counting and autoradiography. Whole blood showed the least activity (1800 cpm/100 lambda at day one, declining to 2800 cpm/100 lambda by day 16). Omentum and diaphragm maintained the greatest concentrations (183 x 10 6 dpm/g and 4 x 10 6 dpm/g respectively). These initial high values were 100 times greater than the highest values found for the small intestine, abdominal wall muscle, mediastinal and retroperitoneal lymph nodes and pleura. The peritoneum increased in specific activity until day three (5.9 x 10 6 dpm/g) and then rapidly declined. Our results show that following IP administration to the dog, 32 P suspension is associated with the serous membranes of the peritoneal cavity (most notably omentum, diaphragm, peritoneum, and retroperitoneum). This distribution could be valuable in adjuvant tumor therapy since serosal surfaces of the peritoneum (both visceral and parietal) and the omentum are the most common sites of tumor metastases associated with ovarian carcinoma

  15. Is temporary employment related to health status? Analysis of the Northern Swedish Cohort.

    Science.gov (United States)

    Waenerlund, Anna-Karin; Virtanen, Pekka; Hammarström, Anne

    2011-07-01

    The aim of this study was to investigate whether temporary employment was related to non-optimal self-rated health and psychological distress at age 42 after adjustment for the same indicators at age 30, and to analyze the effects of job insecurity, low cash margin and high job strain on this relationship. A subcohort of the Northern Swedish Cohort that was employed at the 2007 follow-up survey (n = 907, response rate of 94%) was analyzed using data from 1995 and 2007 questionnaires. Temporary employees had a higher risk of both non-optimal self-rated health and psychological distress. After adjustment for non-optimal self-rated health at age 30 and psychological distress at age 30 as well as for sociodemographic variables, the odds ratios decreased but remained significant. However, after adjustment for job insecurity, high job strain and low cash margin the odds ratio dropped for non-optimal self-rated health but remained significant for psychological distress. Temporary employment may have adverse effects on self-rated health and psychological health after adjustment for previous health status and sociodemographic variables. Our findings indicate that low cash margin and job insecurity may partially mediate the association between temporary employment and health status.

  16. 46 CFR 30.10-45 - Ocean-TB/O.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 1 2010-10-01 2010-10-01 false Ocean-TB/O. 30.10-45 Section 30.10-45 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY TANK VESSELS GENERAL PROVISIONS Definitions § 30.10-45 Ocean—TB/O. Under this designation shall be included all tank vessels normally navigating the waters of any ocean or...

  17. Investigating the little rip and other future singularities of the universe, and validity of the second law of thermodynamics in F(R theory

    Directory of Open Access Journals (Sweden)

    M Aghaei Abchouyeh

    2015-01-01

    Full Text Available The future singularities are possible in a universe that is described by F(R theory. In previous studies the occurrence of the singularities in F(R theory have been considered by using a special function for the Hubble parameter and calculating the F(R function for each of the singularities. Using the specified Hubble parameter causes some difficulties in the study of the second law of thermodynamics. In this paper by using the scale factor, the behavior of F(R function near each type of the singularities is considered. We can check the validity of the second law of thermodynamics near the singularities. At first we study the Little Rip and then the other types of singularities are considered. The results show that the second law of thermodynamics is satisfied near the singularity type (I with some special conditions and is violated with some other conditions. it is satisfied near the Little Rip, type (II, (III and (IV singularities

  18. Trastuzumab produces therapeutic actions by upregulating miR-26a and miR-30b in breast cancer cells.

    Directory of Open Access Journals (Sweden)

    Takehiro Ichikawa

    Full Text Available OBJECTIVE: Trastuzumab has been used for the treatment of HER2-positive breast cancer (BC. However, a subset of BC patients exhibited resistance to trastuzumab therapy. Thus, clarifying the molecular mechanism of trastuzumab treatment will be beneficial to improve the treatment of HER2-positive BC patients. In this study, we identified trastuzumab-responsive microRNAs that are involved in the therapeutic effects of trastuzumab. METHODS AND RESULTS: RNA samples were obtained from HER2-positive (SKBR3 and BT474 and HER2-negetive (MCF7 and MDA-MB-231 cells with and without trastuzumab treatment for 6 days. Next, we conducted a microRNA profiling analysis using these samples to screen those microRNAs that were up- or down-regulated only in HER2-positive cells. This analysis identified miR-26a and miR-30b as trastuzumab-inducible microRNAs. Transfecting miR-26a and miR-30b induced cell growth suppression in the BC cells by 40% and 32%, respectively. A cell cycle analysis showed that these microRNAs induced G1 arrest in HER2-positive BC cells as trastuzumab did. An Annexin-V assay revealed that miR-26a but not miR-30b induced apoptosis in HER2-positive BC cells. Using the prediction algorithms for microRNA targets, we identified cyclin E2 (CCNE2 as a target gene of miR-30b. A luciferase-based reporter assay demonstrated that miR-30b post-transcriptionally reduced 27% (p = 0.005 of the gene expression by interacting with two binding sites in the 3'-UTR of CCNE2. CONCLUSION: In BC cells, trastuzumab modulated the expression of a subset of microRNAs, including miR-26a and miR-30b. The upregulation of miR-30b by trastuzumab may play a biological role in trastuzumab-induced cell growth inhibition by targeting CCNE2.

  19. Isolation and culture of Celosia cristata L cell suspension protoplasts

    Directory of Open Access Journals (Sweden)

    Retno Mastuti

    2003-06-01

    Full Text Available Developmental competence of Celosia cristata L. cell suspension-derived protoplasts was investigated. The protoplasts were isolatedfrom 3- to 9-d old cultures in enzyme solution containing 2% (w/v Cellulase YC and 0.5% (w/v Macerozyme R-10 which was dissolvedin washing solution (0.4 M mannitol and 10 mM CaCl2 at pH 5.6 for 3 hours. The highest number of viable protoplasts was releasedfrom 5-d old culture of a homogenous cell suspension. Subsequently, three kinds of protoplast culture media were simultaneously examinedwith four kinds of concentration of gelling agent. Culturing the protoplasts on KM8p medium solidified with 1.2% agarose significantlyenhanced plating efficiency as well as microcolony formation. Afterwards, the microcalli actively proliferated into friable watery calluswhen they were subcultured on MS medium supplemented with 0.3 mg/l 2,4-D and 1.0 mg/l kinetin. Although the plant regenerationfrom the protoplasts-derived calli has not yet been obtained, the reproducible developmental step from protoplasts to callus in thisstudy may facilitate the establishment of somatic hybridization using C. cristata as one parent.

  20. 76 FR 43376 - Order Granting Temporary Exemptions From Certain Government Securities Act Provisions and...

    Science.gov (United States)

    2011-07-20

    .../gsareg.htm . As noted in its request, on July 16, 2011, ICE Trust reorganized its corporate structure... DEPARTMENT OF THE TREASURY Order Granting Temporary Exemptions From Certain Government Securities... temporary exemptions from certain Government Securities Act of 1986 provisions and regulations regarding...

  1. Large capacity temporary visual memory

    Science.gov (United States)

    Endress, Ansgar D.; Potter, Mary C.

    2014-01-01

    Visual working memory (WM) capacity is thought to be limited to three or four items. However, many cognitive activities seem to require larger temporary memory stores. Here, we provide evidence for a temporary memory store with much larger capacity than past WM capacity estimates. Further, based on previous WM research, we show that a single factor — proactive interference — is sufficient to bring capacity estimates down to the range of previous WM capacity estimates. Participants saw a rapid serial visual presentation (RSVP) of 5 to 21 pictures of familiar objects or words presented at rates of 4/s or 8/s, respectively, and thus too fast for strategies such as rehearsal. Recognition memory was tested with a single probe item. When new items were used on all trials, no fixed memory capacities were observed, with estimates of up to 9.1 retained pictures for 21-item lists, and up to 30.0 retained pictures for 100-item lists, and no clear upper bound to how many items could be retained. Further, memory items were not stored in a temporally stable form of memory, but decayed almost completely after a few minutes. In contrast, when, as in most WM experiments, a small set of items was reused across all trials, thus creating proactive interference among items, capacity remained in the range reported in previous WM experiments. These results show that humans have a large-capacity temporary memory store in the absence of proactive interference, and raise the question of whether temporary memory in everyday cognitive processing is severely limited as in WM experiments, or has the much larger capacity found in the present experiments. PMID:23937181

  2. 49 CFR 592.7 - Suspension, revocation, and reinstatement of suspended registrations.

    Science.gov (United States)

    2010-10-01

    ... vehicle during the time that its registration has been suspended. (d) Effect of suspension or revocation... date of the suspension or revocation all vehicles that it imported to which it has not affixed a... 49 Transportation 7 2010-10-01 2010-10-01 false Suspension, revocation, and reinstatement of...

  3. Permanent and temporary pacemaker implantation after orthotopic heart transplantation

    Directory of Open Access Journals (Sweden)

    Bacal Fernando

    2000-01-01

    Full Text Available PURPOSE:To determine the indication for and incidence and evolution of temporary and permanent pacemaker implantation in cardiac transplant recipients. METHODS: A retrospective review of 114 patients who underwent orthotopic heart transplantation InCor (Heart Institute USP BR between March 1985 and May 1993. We studied the incidence of and indication for temporary pacing, the relationship between pacing and rejection, the need for pemanent pacing and the clinical follow-up. RESULTS: Fourteen of 114 (12%heart transplant recipients required temporary pacing and 4 of 114 (3.5% patients required permanent pacing. The indication for temporary pacing was sinus node dysfunction in 11 patients (78.5% and atrioventricular (AV block in 3 patients (21.4%. The indication for permanent pacemaker implantation was sinus node dysfunction in 3 patients (75% and atrioventricular (AV block in 1 patient (25%. We observed rejection in 3 patients (21.4% who required temporary pacing and in 2 patients (50% who required permanent pacing. The previous use of amiodarone was observed in 10 patients (71.4% with temporary pacing. Seven of the 14 patients (50% died during follow-up. CONCLUSION: Sinus node dysfunction was the principal indication for temporary and permanent pacemaker implantation in cardiac transplant recipients. The need for pacing was related to worse prognosis after cardiac transplantation.

  4. Phagocytosis in phosphate chromium (III) suspensions

    International Nuclear Information System (INIS)

    Cruz-Arencibia, Jorge; Fano Machín, Yoiz; Cruz-Morales, Ahmed; Tamayo Fuente, Radamés; Morín-Zorrilla, José

    2015-01-01

    Phagocytosis in vivo and in vitro of a suspension of chromic phosphate (III) labeled with 51 Cr and 32 P is studied. The radioactive particles dispersed in a media of 2 % gelatin in acetate buffer pH 4-4.5 have a predominant size of 0.8 μm and 5 μm. According with biodistribution experiments in rats after 30 minutes near the 80 % of radioactivity is registered in the liver, probably associated with phagocytosis of the particles by liver Kupffer cells. Is also showed that the suspension particles are phagocytized in vitro by mouse peritoneal macrophages. This facts indicate that the studied suspension have appropriate characteristics to be used in radiosynoviorthesis according to the principal action mechanism described for this procedure, particles phagocytosis by cells present in the inflamed synovium. (author)

  5. Assessment of drug salt release from solutions, suspensions and in situ suspensions using a rotating dialysis cell

    DEFF Research Database (Denmark)

    Parshad, Henrik; Frydenvang, Karla; Liljefors, Tommy

    2003-01-01

    buffer is used as release media. Generally, the initial release of the drug salt from in situ suspensions occurred faster as compared to conventional suspensions, probably due to incomplete precipitation of the drug salt, and hence formation of supersaturated solutions where the rate of release......A rotating dialysis cell consisting of a small (10 ml) and a large compartment (1000 ml) was used to study the release of drug salt (bupivacaine 9-anthracene carboxylate) from (i). solutions, (ii). suspensions and (iii). in situ formed suspensions. Initial release experiments from suspensions...... indicated that the release of drug salt in deionized water was predominantly limited by the diffusion across the membrane whereas it is essentially dissolution rate controlled in 0.05 M phosphate buffer (pH 7.40). Thus, the in vitro model appears to have a potential in formulation screening when phosphate...

  6. 78 FR 35533 - Suspension of Limitations Under the Jerusalem Embassy Act

    Science.gov (United States)

    2013-06-12

    ...-09 of June 4, 2013--Suspension of Limitations Under the Jerusalem Embassy Act Presidential.... 2013-09 of June 4, 2013 Suspension of Limitations Under the Jerusalem Embassy Act Memorandum for the... the United States, including section 7(a) of the Jerusalem Embassy Act of 1995 (Public Law 104-45...

  7. 10 CFR 30.7 - Employee protection.

    Science.gov (United States)

    2010-01-01

    ... occurs because the employee has engaged in protected activities. An employee's engagement in protected... 10 Energy 1 2010-01-01 2010-01-01 false Employee protection. 30.7 Section 30.7 Energy NUCLEAR... Provisions § 30.7 Employee protection. (a) Discrimination by a Commission licensee, an applicant for a...

  8. Stability of an extemporaneously prepared tadalafil suspension.

    Science.gov (United States)

    Pettit, Rebecca S; Johnson, Cary E; Caruthers, Regine L

    2012-04-01

    The stability of an extemporaneously prepared tadalafil oral suspension was studied. An oral suspension of tadalafil 5 mg/mL was prepared by thoroughly grinding 15 20-mg tadalafil tablets in a glass mortar. Thirty milliliters of Ora-Plus and 30 mL of Ora-Sweet were mixed and added to the powder to make a final volume of 60 mL. Three identical samples of the formulation were prepared and placed in 2-oz amber plastic bottles with child-resistant caps and stored at room temperature (23-25 °C). A 1-mL sample was withdrawn from each of the three bottles with a micropipette immediately after preparation and at 7, 14, 28, 57, and 91 days. After double dilution (1:10 and 0.1:5 v/v) to an expected concentration of 10 μg/mL with methanol and mobile phase, respectively, the samples were assayed in duplicate using stability-indicating high-performance liquid chromatography. The samples were visually examined for any color change and evaluated for pH changes on each day of analysis. Taste evaluation was performed at the beginning and end of the study. Stability was defined as the retention of at least 90% of the initial concentration. At least 99% of the initial tadalafil concentration remained throughout the 91-day study period. There were no detectable changes in color, odor, taste, and pH, and no visible microbial growth was observed in any sample. An extemporaneously prepared suspension of tadalafil 5 mg/mL in a 1:1 mixture of Ora-Plus and Ora-Sweet was stable for at least 91 days when stored in amber plastic bottles at room temperature.

  9. Early closure of temporary ileostomy--the EASY trial

    DEFF Research Database (Denmark)

    Danielsen, Anne Kjaergaard; Correa-Marinez, Adiela; Angenete, Eva

    2011-01-01

    Reversal of a temporary ileostomy is generally associated with a low morbidity and mortality. However, ostomy reversal may cause complications requiring reoperation with subsequent major complications, in ranges from 0% to 7-9% and minor complications varying from 4-5% to 30%. Based on studies exploring...

  10. 78 FR 23952 - Notice of Temporary Closure on Public Lands in Elmore County, ID

    Science.gov (United States)

    2013-04-23

    ...] Notice of Temporary Closure on Public Lands in Elmore County, ID AGENCY: Bureau of Land Management, Interior. ACTION: Notice of temporary closure. SUMMARY: Notice is hereby given that the Stout Fire closure to motorized vehicle use is in effect on public lands administered by the Four Rivers Field Office...

  11. Thin-shell wormholes with charge in F(R) gravity

    Energy Technology Data Exchange (ETDEWEB)

    Eiroa, Ernesto F. [Instituto de Astronomia y Fisica del Espacio (IAFE, CONICET-UBA), Buenos Aires (Argentina); Universidad de Buenos Aires, Departamento de Fisica, Facultad de Ciencias Exactas y Naturales, Buenos Aires (Argentina); Figueroa Aguirre, Griselda [Instituto de Astronomia y Fisica del Espacio (IAFE, CONICET-UBA), Buenos Aires (Argentina)

    2016-03-15

    In this article, we construct a class of constant curvature and spherically symmetric thin-shell Lorentzian wormholes in F(R) theories of gravity and we analyze their stability under perturbations preserving the symmetry. We find that the junction conditions determine the equation of state of the matter at the throat. As a particular case, we consider configurations with mass and charge. We obtain that stable static solutions are possible for suitable values of the parameters of the model. (orig.)

  12. Thin-shell wormholes with charge in F(R) gravity

    International Nuclear Information System (INIS)

    Eiroa, Ernesto F.; Figueroa Aguirre, Griselda

    2016-01-01

    In this article, we construct a class of constant curvature and spherically symmetric thin-shell Lorentzian wormholes in F(R) theories of gravity and we analyze their stability under perturbations preserving the symmetry. We find that the junction conditions determine the equation of state of the matter at the throat. As a particular case, we consider configurations with mass and charge. We obtain that stable static solutions are possible for suitable values of the parameters of the model. (orig.)

  13. 78 FR 20135 - Notice of Temporary Closure on Public Lands in Boise County, ID

    Science.gov (United States)

    2013-04-03

    ...] Notice of Temporary Closure on Public Lands in Boise County, ID AGENCY: Bureau of Land Management, Interior. ACTION: Notice of Temporary Closure SUMMARY: Notice is hereby given that the Springs Fire closure to all human use is in effect on public lands administered by the Four Rivers Field Office, Bureau of...

  14. 76 FR 82071 - Suspension of Limitations Under the Jerusalem Embassy Act

    Science.gov (United States)

    2011-12-29

    .... 2012-03 of December 2, 2011--Suspension of Limitations Under the Jerusalem Embassy Act #0; #0; #0.... 2012-03 of December 2, 2011 Suspension of Limitations Under the Jerusalem Embassy Act Memorandum for... laws of the United States, including section 7(a) of the Jerusalem Embassy Act of 1995 (Public Law 104...

  15. 77 FR 74551 - Suspension of Limitations Under the Jerusalem Embassy Act

    Science.gov (United States)

    2012-12-14

    .... 2013-2 of December 4, 2012--Suspension of Limitations Under the Jerusalem Embassy Act #0; #0; #0.... 2013-2 of December 4, 2012 Suspension of Limitations Under the Jerusalem Embassy Act Memorandum for the... the United States, including section 7(a) of the Jerusalem Embassy Act of 1995 (Public Law 104-45...

  16. 10 CFR 30.55 - Tritium reports.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 1 2010-01-01 2010-01-01 false Tritium reports. 30.55 Section 30.55 Energy NUCLEAR..., Inspections, Tests, and Reports § 30.55 Tritium reports. (a)-(b) [Reserved] (c) Except as specified in paragraph (d) of this section, each licensee who is authorized to possess tritium shall report promptly to...

  17. miR-30a suppresses osteosarcoma proliferation and metastasis by downregulating MEF2D expression

    Directory of Open Access Journals (Sweden)

    Du L

    2018-04-01

    Full Text Available Liuxue Du,* Tianpei Chen,* Kai Zhao,* Dong Yang Department of Orthopedics, the First Affiliated Hospital of Nanchang University, Nanchang, People’s Republic of China *These authors contributed equally to this work Abstract: Many studies have revealed that microRNAs (miRNAs play crucial roles in cancer development and progression. miRNA-30a (miR-30a, as a member of the miR-30 family, has been implicated in various cancers. However, the role of miR-30a in osteosarcoma remains unclear. In the current study, we found that miR-30a was significantly downregulated in osteosarcoma tissues and cell lines by using quantitative real-time polymerase chain reaction (qRT-PCR. In addition, miR-30a could inhibit cancer cell growth, migration, and invasion in vitro. Furthermore, bioinformatics of miRNA target prediction and luciferase reporter assay indicated that MEF2D is a direct target of miR-30a. miR-30a was able to reduce the mRNA and protein expression of MEF2D as assessed using RT-PCR and Western blotting assay. Interestingly, overexpression of MEF2D partially reversed the miR-30a-reduced cell proliferation, migration, and invasion of osteosarcoma cell, indicating that miR-30a suppresses osteosarcoma cell proliferation and metastasis partially mediated by inhibition of MEF2D. Overall, our study demonstrated that miR-30a functions as a tumor suppressor by targeting MEF2D in osteosarcoma, providing a promising prognostic biomarker and a therapeutic strategy for osteosarcoma. Keywords: miR-30a, MEF2D, osteosarcoma, proliferation, invasion, migration

  18. Coronal microleakage with five different temporary restorative materials following walking bleach technique: An ex-vivo study

    Directory of Open Access Journals (Sweden)

    G. P. V Srikumar

    2012-01-01

    Full Text Available Context: Walking bleach technique uses 30% hydrogen peroxide and sodium perborate, and this paste mixture causes loosening of the coronal temporary restorative materials and thus decreasing its clinical effectiveness and causing irritation to the patients oral tissues. In the present study, sealing ability of hygroscopic coronal temporary restorative materials were compared with the other commonly used temporary restorative materials. Aim: To evaluate the effects of walking bleach material on the marginal sealing ability and coronal microleakage of the hydrophilic temporary restorative materials with that of the other commonly used temporary restorative materials in endodontic practice. Materials and Methods: Seventy-five extracted human maxillary central incisor teeth were prepared chemo-mechanically and obturated with gutta-percha in lateral condensation technique. Surface of each tooth was double coated with cyanoacrylate glue. All the teeth were randomly divided in to five groups. Out of 15 teeth in each group, 10 teeth served as experimental specimens, in which bleaching agent was placed in the pulp chamber and 5 teeth served as control, in which no bleaching agent was placed. The access cavities were restored with temporary restorative materials being tested per each group respectively. The specimens were then immersed in 1% India ink dye and subjected to thermo cycling for 7 days. All the teeth were longitudinally sectioned and observed with stereomicroscope and were graded according to the depth of linear dye penetration. Statistical Analysis Used: Mann-Whitney U test and Kruskal-Wallis test. Results: Hydrophilic temporary restorative materials Cavit G and Coltosol F have shown minimal coronal dye leakage with better sealing ability when exposed to walking bleach paste mixture in the dye penetration tests compared to other commonly used temporary restorative materials. Conclusion: Marginal sealing ability of Cavit G and Coltosol F were

  19. miR-30a suppresses breast cancer cell proliferation and migration by targeting Eya2

    International Nuclear Information System (INIS)

    Fu, Jing; Xu, Xiaojie; Kang, Lei; Zhou, Liying; Wang, Shibin; Lu, Juming; Cheng, Long; Fan, Zhongyi; Yuan, Bin; Tian, Peirong; Zheng, Xiaofei; Yu, Chengze; Ye, Qinong; Lv, Zhaohui

    2014-01-01

    Highlights: • miR-30a represses Eya2 expression by binding to the 3′-untranslated region of Eya2. • The miR-30a/EYA2 axis regulates breast cancer cell proliferation and migration. • The miR-30a/EYA2 axis modulates G1/S cell cycle progression. • The miR-30a/EYA2 axis is dysregulated in breast cancer patients. - Abstract: Eye absent (Eya) proteins are involved in cell fate determination in a broad spectrum of cells and tissues. Aberrant expression of Eya2 has been documented in a variety of cancers and correlates with clinical outcome. However, whether microRNAs (miRNAs) can regulate Eya2 expression remains unknown. Here, we show that miR-30a represses Eya2 expression by binding to the 3′-untranslated region of Eya2. Overexpression of Eya2 in miR-30a-transfected breast cancer cells effectively rescued the inhibition of cell proliferation and migration caused by miR-30a. Knockdown of Eya2 by small-interfering RNA (siRNA) in breast cancer cells mimicked the effect induced by miR-30a and abolished the ability of miR-30a to regulate breast cancer cell proliferation and migration. The miR-30a/Eya2 axis could regulate G1/S cell cycle progression, accompanied by the modulation of expression of cell cycle-related proteins, including cyclin A, cyclin D1, cyclin E, and c-Myc. Moreover, miR-30a expression was downregulated in breast cancer patients, and negatively correlated with Eya2, which was upregulated in breast cancer patients. These data suggest that the miR-30a/Eya2 axis may play an important role in breast cancer development and progression and that miR-30a activation or Eya2 inhibition may be a useful strategy for cancer treatment

  20. Stability and uniformity of extemporaneous preparations of voriconazole in two liquid suspension vehicles at two storage temperatures.

    Science.gov (United States)

    Nguyen, Kyvan Q; Hawkins, Michelle G; Taylor, Ian T; Wiebe, Valerie J; Tell, Lisa A

    2009-07-01

    To determine the stability and distribution of voriconazole in 2 extemporaneously prepared (compounded) suspensions stored for 30 days at 2 temperatures. Voriconazole suspensions (40 mg/mL) compounded from commercially available 200-mg tablets suspended in 1 of 2 vehicles. One vehicle contained a commercially available suspending agent and a sweetening syrup in a 1:1 mixture (SASS). The other vehicle contained the suspending agent with deionized water in a 3:1 mixture (SADI). Voriconazole suspensions (40 mg/mL in 40-mL volumes) were compounded on day 0 and stored at room temperature (approx 21 degrees C) or refrigerated (approx 5 degrees C). To evaluate distribution, room-temperature aliquots of voriconazole were measured immediately after preparation. Refrigerated aliquots were measured after 3 hours of refrigeration. To evaluate stability, aliquots from each suspension were measured at approximately 7-day intervals for up to 30 days. Voriconazole concentration, color, odor, opacity, and pH were measured, and aerobic and anaerobic bacterial cultures were performed at various points. Drug distribution was uniform (coefficient of variation, suspensions. On day 0, 87.8% to 93.0% of voriconazole was recovered; percentage recovery increased to between 95.1% and 100.8% by day 7. On subsequent days, up to day 30, percentage recovery was stable (> 90%) for all suspensions. The pH of each suspension did not differ significantly throughout the 30-day period. Storage temperature did not affect drug concentrations at any time, nor was bacterial growth obtained. Extemporaneously prepared voriconazole in SASS and SADI resulted in suspensions that remained stable for at least 30 days. Refrigerated versus room-temperature storage of the suspensions had no effect on drug stability.

  1. 25 CFR 11.607 - Temporary orders and temporary injunctions.

    Science.gov (United States)

    2010-04-01

    ... injunction: (1) Does not prejudice the rights of the parties or the child which are to be adjudicated at... temporary maintenance or temporary support of a child of the marriage entitled to support. The motion shall... the peace of the other party or of any child; (3) Excluding a party from the family home or from the...

  2. Synchrotron SAXS/WAXD and rheological studies of clay suspensions in silicone fluid.

    Science.gov (United States)

    Zhang, Li-Ming; Jahns, Christopher; Hsiao, Benjamin S; Chu, Benjamin

    2003-10-15

    Suspensions of two commercial smectite clays, montmorillonite KSF and montmorillonite K10, in a low-viscosity silicone oil (Dow Corning 245 Fluid) were studied by simultaneous synchrotron small-angle X-ray scattering (SAXS)/wide-angle X-ray diffraction (WAXD) techniques and rheological measurements. In the 0.5% (w/v) KSF clay suspension and two K10 clay suspensions (0.5% and 1.0%), WAXD profiles below 2theta=10.0 degrees did not display any characteristic reflection peaks associated with the chosen montmorillonite clays, while corresponding SAXS profiles exhibited distinct scattering maxima, indicating that both clays were delaminated by the silicone oil. In spite of the large increase in viscosity, the clay suspensions exhibited no gel characteristics. Dynamic rheological experiments indicated that the clay/silicone oil suspensions exhibited the behavior of viscoelasticity, which could be influenced by the type and the concentration of the clay. For the K10 clay suspensions, the frequency-dependent loss modulus (G") was greater in magnitude than the storage modulus (G') in the concentration range from 0.5 to 12.0%. The increase in the clay concentration shifted the crossover point between G' and G" into the accessible frequency range, indicating that the system became more elastic. In contrast, the KSF clay suspension exhibited lower G' and G" values, indicating a weaker viscoelastic response. The larger viscoelasticity response in the K10 clay suspension may be due to the acid treatment generating a higher concentration of silanol groups on the clay surface.

  3. 75 FR 47199 - Airworthiness Directives; McDonnell Douglas Corporation Model DC-9-10 Series Airplanes, DC-9-30...

    Science.gov (United States)

    2010-08-05

    ... Airworthiness Directives; McDonnell Douglas Corporation Model DC- 9-10 Series Airplanes, DC-9-30 Series... existing airworthiness directive (AD), which applies to all McDonnell Douglas Model DC-9-10 series..., 2010). That AD applies to all McDonnell Douglas Corporation Model DC-9-10 series airplanes, DC-9-30...

  4. 76 FR 35909 - Temporary Concession Contract for Blue Ridge Parkway

    Science.gov (United States)

    2011-06-20

    ... accommodations, food and beverage, retail sales, boat rentals, and other services at Crabtree Falls, Price Lake... DEPARTMENT OF THE INTERIOR National Park Service [NPS-WASO-CONC-0511-7182; 2410-OYC] Temporary Concession Contract for Blue Ridge Parkway AGENCY: National Park Service, Interior. ACTION: Notice of...

  5. N-body simulations for f(R) gravity using a self-adaptive particle-mesh code

    Science.gov (United States)

    Zhao, Gong-Bo; Li, Baojiu; Koyama, Kazuya

    2011-02-01

    We perform high-resolution N-body simulations for f(R) gravity based on a self-adaptive particle-mesh code MLAPM. The chameleon mechanism that recovers general relativity on small scales is fully taken into account by self-consistently solving the nonlinear equation for the scalar field. We independently confirm the previous simulation results, including the matter power spectrum, halo mass function, and density profiles, obtained by Oyaizu [Phys. Rev. DPRVDAQ1550-7998 78, 123524 (2008)10.1103/PhysRevD.78.123524] and Schmidt [Phys. Rev. DPRVDAQ1550-7998 79, 083518 (2009)10.1103/PhysRevD.79.083518], and extend the resolution up to k˜20h/Mpc for the measurement of the matter power spectrum. Based on our simulation results, we discuss how the chameleon mechanism affects the clustering of dark matter and halos on full nonlinear scales.

  6. Quantitative proteome changes in Arabidopsis thaliana suspension-cultured cells in response to plant natriuretic peptides

    KAUST Repository

    Turek, Ilona; Wheeler, Janet I.; Gehring, Christoph A; Irving, Helen R.; Marondedze, Claudius

    2015-01-01

    Proteome changes in the Arabidopsis thaliana suspension cells in response to the A. thaliana plant natriuretic peptide (PNP), AtPNP-A (At2g18660) were assessed using quantitative proteomics employing tandem mass tag (TMT) labeling and tandem mass spectrometry (LC–MS/MS). In this study, we characterized temporal responses of suspension-cultured cells to 1 nM and 10 pM AtPNP-A at 0, 10 and 30 min post-treatment. Both concentrations we found to yield a distinct differential proteome signature. The data shown in this article are associated with the article “Plant natriuretic peptides induce a specific set of proteins diagnostic for an adaptive response to abiotic stress” by Turek et al. (Front. Plant Sci. 5 (2014) 661) and have been deposited to the ProteomeXchange with identifier PXD001386.

  7. Quantitative proteome changes in Arabidopsis thaliana suspension-cultured cells in response to plant natriuretic peptides

    KAUST Repository

    Turek, Ilona

    2015-06-30

    Proteome changes in the Arabidopsis thaliana suspension cells in response to the A. thaliana plant natriuretic peptide (PNP), AtPNP-A (At2g18660) were assessed using quantitative proteomics employing tandem mass tag (TMT) labeling and tandem mass spectrometry (LC–MS/MS). In this study, we characterized temporal responses of suspension-cultured cells to 1 nM and 10 pM AtPNP-A at 0, 10 and 30 min post-treatment. Both concentrations we found to yield a distinct differential proteome signature. The data shown in this article are associated with the article “Plant natriuretic peptides induce a specific set of proteins diagnostic for an adaptive response to abiotic stress” by Turek et al. (Front. Plant Sci. 5 (2014) 661) and have been deposited to the ProteomeXchange with identifier PXD001386.

  8. Electrorheology of aniline-oligomer suspensions under oscillatory shear

    Czech Academy of Sciences Publication Activity Database

    Mrlík, M.; Pavlínek, V.; Almajdalawi, S.; Saha, P.; Bober, Patrycja; Stejskal, Jaroslav

    2013-01-01

    Roč. 412, č. 1 (2013), 012007_1-012007_6 ISSN 1742-6588. [International Conference on Electrorheological Fluids and Magnetorheological Suspensions /13./ - ERMR2012. Ankara, 02.07.2012-06.07.2012] R&D Projects: GA ČR GA202/09/1626 Institutional support: RVO:61389013 Keywords : electrorheology * polyaniline * conducting polymer Subject RIV: BK - Fluid Dynamics

  9. 77 FR 12723 - Labor Certification Process for the Temporary Employment of Aliens in Agriculture in the United...

    Science.gov (United States)

    2012-03-02

    ... the Temporary Employment of Aliens in Agriculture in the United States; Announcement of Non- Material... reasons in great detail in the preamble of the ``Temporary Agricultural Employment of H-2A Aliens in the... set the AEWR. See ``Temporary Agricultural Employment of H-2A Aliens in the United States; Modernizing...

  10. Progress report of the Nuclear Physics Department (1.10.1980-30.9.1981)

    International Nuclear Information System (INIS)

    1982-04-01

    This progress report presents the experiments and the technological studies carried out at the Nuclear Physics Department of Saclay from October 1, 1980 to September 30, 1981. These studies concern the structure of nuclei and hypernuclei and various reaction mechanisms. They have been performed with the 8.5 MV tandem Van de Graaff, with the 600 MeV electron linac, at the synchrotron SATURNE and with different accelerators belonging to other laboratories [fr

  11. Scaling-up the biomass production of Cymbopogon citratus L. in temporary immersion system

    Directory of Open Access Journals (Sweden)

    Elisa Quiala

    2014-04-01

    Full Text Available Shoot-tips, collected from greenhouse-grown plants of Cymbopogon citratus L. (lemmon grass, were incubated on a semi-solid Murashige and Skoog (MS medium with 30% (w/v sucrose, and supplemented with 0.89 µM 6-benzyladenine (BA. After three weeks of culture shoots were individualized and then inoculated in 10 litres temporary immersion system (TIS containing 3 litres of the same basal MS liquid medium. The effects of three immersion frequency (immersion every 12, 6 and 4 hours on the production of biomass were studied. Three inoculum densities (forty, fifty and sixty shoots/TIS were also tested. The biomass growth was inûuenced by the immersion frequency. The highest proliferation rate (17.3 shoots/explants and the plant length (45.2 cm were obtained in plants immersed every 4 h. Also, the fresh and dry biomass weight (153.4 gFW and 24.8 gDW, respectively were higher in this treatment. The maximum biomass accumulation (185.2 gFW and 35.2 gDW was achieved after 30 days of culture when an inoculum density of 60 explants per TIS was used. For the first time, biomass of C. citratus has been produced in10 litres TIS. These results represent the first step in the scaling-up the biomass production of this medicinal plant in large temporary immersion bioreactors. Key words: automation, biomass growth, lemmon grass medicinal plant, tissue culture

  12. A blockchain-based Decentralized System for proper handling of temporary Employment contracts

    OpenAIRE

    Pinna, Andrea; Ibba, Simona

    2017-01-01

    Temporary work is an employment situation useful and suitable in all occasions in which business needs to adjust more easily and quickly to workload fluctuations or maintain staffing flexibility. Temporary workers play therefore an important role in many companies, but this kind of activity is subject to a special form of legal protections and many aspects and risks must be taken into account both employers and employees. In this work we propose a blockchain-based system that aims to ensure r...

  13. 76 FR 78739 - Agency Information Collection (Regulation on Application for Fisher Houses and Other Temporary...

    Science.gov (United States)

    2011-12-19

    ... DEPARTMENT OF VETERANS AFFAIRS [OMB Control No. 2900-0630] Agency Information Collection (Regulation on Application for Fisher Houses and Other Temporary Lodging and VHA Fisher House Application... INFORMATION: Title: Regulation on Application for Fisher Houses and Other Temporary Lodging and VHA Fisher...

  14. 75 FR 4626 - Order Granting a Temporary Exemption From Certain Government Securities Act Provisions and...

    Science.gov (United States)

    2010-01-28

    ... DEPARTMENT OF THE TREASURY Order Granting a Temporary Exemption From Certain Government Securities... Department of the Treasury (Treasury) is issuing a temporary exemption from certain Government Securities Act... accommodate customer clearing of credit default swaps that reference government securities. Treasury is also...

  15. Numerical study of heat and mass transfer in inertial suspensions in pipes.

    Science.gov (United States)

    Niazi Ardekani, Mehdi; Brandt, Luca

    2017-11-01

    Controlling heat and mass transfer in particulate suspensions has many important applications such as packed and fluidized bed reactors and industrial dryers. In this work, we study the heat and mass transfer within a suspension of spherical particles in a laminar pipe flow, using the immersed boundary method (IBM) to account for the solid fluid interactions and a volume of fluid (VoF) method to resolve temperature equation both inside and outside of the particles. Tracers that follow the fluid streamlines are considered to investigate mass transfer within the suspension. Different particle volume fractions 5, 15, 30 and 40% are simulated for different pipe to particle diameter ratios: 5, 10 and 15. The preliminary results quantify the heat and mass transfer enhancement with respect to a single-phase laminar pipe flow. We show in particular that the heat transfer from the wall saturates for volume fractions more than 30%, however at high particle Reynolds numbers (small diameter ratios) the heat transfer continues to increase. Regarding the dispersion of tracer particles we show that the diffusivity of tracers increases with volume fraction in radial and stream-wise directions however it goes through a peak at 15% in the azimuthal direction. European Research Council, Grant No. ERC-2013-CoG- 616186, TRITOS; SNIC (the Swedish National Infrastructure for Computing).

  16. 78 FR 2622 - Suspension of Community Eligibility

    Science.gov (United States)

    2013-01-14

    ..., 2013 Feb. 6, 2013. Middlesex County. Emerg; September 30, 1980, Reg; February 6, 2013, Susp. Essex, Town of, Middlesex 090065 February 9, 1973, ......do Do. County. Emerg; July 16, 1980, Reg; February 6, 2013, Susp. Fenwick, Borough of, 090187 July 10, 1979, ......do Do. Middlesex County. Emerg; July 10...

  17. Standard format and content of financial assurance mechanisms required for decommissioning under 10 CFR parts 30, 40, 70, and 72

    International Nuclear Information System (INIS)

    1990-01-01

    The Nuclear Regulatory Commission (NRC) has established technical and financial regulations for decommissioning licensed nuclear facilities (53 FR 24018, June 27, 1988). The regulations address decommissioning planning needs, timing, funding methods, and environmental review requirements for public and private facilities holding licenses under 10 CFR Parts 30, 40, 50, 70, and 72, with the exception of uranium mills. The intent of the regulations is to ensure that the decommissioning of all licensed facilities will be accomplished in a safe and timely manner and that licensees will provide adequate funds to cover all costs associated with decommissioning. The purpose of this regulatory guide, ''Standard Format and Content of Financial Assurance Mechanisms Required for Decommissioning Under 10 CFR Parts 30, 40, 70, and 72,'' is to provide guidance acceptable to the NRC staff on the information to be provided for establishing financial assurance for decommissioning and to establish a standard format for presenting the information. Use of the standard format will (1) help ensure that the financial instruments contain the information required by 10 CFR Parts 30, 40, 70, and 72, (2) aid the applicant and NRC staff in ensuring that the information is complete, and (3) help persons reading the financial instruments to locate information. 5 refs., 13 figs

  18. Bioinformatics prediction of miR-30a targets and its inhibition of cell proliferation of osteosarcoma by up-regulating the expression of PTEN

    Directory of Open Access Journals (Sweden)

    Biao Zhong

    2017-11-01

    Full Text Available Abstract Background MiRNAs are frequently abnormally expressed in the progression of human osteosarcoma. Phosphatase and tensin homologue deleted on chromosome 10 (PTEN is one of the tumor suppressors in various types of human cancer. In the present study, we detected how hsa-miR-30a-3p regulated PTEN and further tested the role of hsa-miR-30a-3p in the cell proliferation of osteosarcoma cells. Methods The levels of miR-30a were determined by real time PCR. The expression of PTEN was tested by western blotting analysis. Cell distribution of PTEN was observed with confocal laser scanning microscope. Cell viability was determined by MTT assay. Results The expression of miR-30a and PTEN was obviously decreased in MG-63, 143B and Saos-2 cells compared with primary osteoblasts. TargetScan analysis data showed miR-30a might bind with position 30-57 of 3’UTR of PTEN. Transfection with miR-30a-3p increased the level of PTEN in MG-63 cells, while transfection with miR-30a-3p inhibitor significantly decreased the expression of PTEN in osteosarcoma cells. Transfection with miR-30a-3p significantly inhibited cell proliferation of osteosarcoma cells, while miR-30a inhibitor obviously promoted cell viability of MG63 cells and Saos-2 cells. Inhibition of PTEN eliminated the proliferation inhibitory effect of miR-30a-3p. Conclusion Thus, all these findings revealed the anti-tumor effects of miR-30a in human osteosarcoma cells, which could be mediated by regulating the level of PTEN.

  19. Simultaneous detection for three kinds of veterinary drugs: Chloramphenicol, clenbuterol and 17-beta-estradiol by high-throughput suspension array technology

    Energy Technology Data Exchange (ETDEWEB)

    Liu Nan; Su Pu [Institute of Hygiene and Environmental Medicine, Tianjin 300050 (China); Gao Zhixian [Institute of Hygiene and Environmental Medicine, Tianjin 300050 (China)], E-mail: gaozhx@163.com; Zhu Maoxiang; Yang Zhihua; Pan Xiujie [Institute of Radiation Medicine, Beijing 100850 (China); Fang Yanjun; Chao Fuhuan [Institute of Hygiene and Environmental Medicine, Tianjin 300050 (China)

    2009-01-19

    Suspension array technology for simultaneous detection of three kinds of veterinary drugs, chloramphenicol (CAP), clenbuterol and 17-beta-estradiol has been developed. Conjugates of chloramphenicol and clenbuterol coupled with bovine serum albumin were synthesized and purified. Probes of suspension array were constituted by coupling the three conjugates on the fluorescent microspheres/beads and the microstructures of the beads' surface were observed by scanning electron microscopy which was a direct confirmation for the successful conjugates' coupling. The optimal addition of conjugates and the amounts of antibodies were optimized and selected, respectively. Standard curves were plotted and the coefficient of determination-R{sup 2} was greater than 0.989 which suggested good logistic correlation. The detection ranges for the three veterinary drugs are 40-6.25 x 10{sup 5} ng L{sup -1}, 50-7.81 x 10{sup 5} ng L{sup -1} and 1 x 10{sup 3-}7.29 x 10{sup 5} ng L{sup -1}, respectively and the lowest detection limits (LDLs) of them are 40, 50 and 1000 ng L{sup -1}, respectively. The suspension array is specific and has no significant cross-reactivity with other chemicals. Meanwhile, unknown samples were detected by suspension array and ELISA in comparison with each other. The errors between found and real for the detection of the unknown samples were relatively small to both of the two methods, whereas, the detection ranges of suspension array are broader and sensitive than that of the traditional ELISA. The high-throughput suspension array is proved to be a novel method for multi-analysis of veterinary drugs with simple operation, high sensitivity and low cost.

  20. 46 CFR 30.10-33 - Great Lakes-TB/L.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 1 2010-10-01 2010-10-01 false Great Lakes-TB/L. 30.10-33 Section 30.10-33 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY TANK VESSELS GENERAL PROVISIONS Definitions § 30.10-33 Great Lakes—TB/L. Under this designation shall be included all tank vessels navigating the Great Lakes. ...

  1. 77 FR 34935 - Foreign-Trade Zone 161; Temporary/Interim Manufacturing Authority; Siemens Energy, Inc., (Wind...

    Science.gov (United States)

    2012-06-12

    ... DEPARTMENT OF COMMERCE Foreign-Trade Zones Board [Docket T-4-2012] Foreign-Trade Zone 161; Temporary/Interim Manufacturing Authority; Siemens Energy, Inc., (Wind Turbine Nacelles and Hubs); Notice of... temporary/interim manufacturing (T/IM) authority, on behalf of Siemens Energy, Inc., to manufacture wind...

  2. 76 FR 16821 - Gregory F. Saric, M.D.; Decision and Order

    Science.gov (United States)

    2011-03-25

    ... Motion to Require the Government to Serve Pleadings Via Facsimile. I granted that motion on October 21... this matter and the temporary nature of the suspension of the Respondent's medical license.'' (Resp't...

  3. 78 FR 64143 - 30-Day Notice of Proposed Information Collection: Contractor's Requisition-Project Mortgages

    Science.gov (United States)

    2013-10-25

    ... DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT [Docket No. FR-5683-N-88] 30-Day Notice of Proposed Information Collection: Contractor's Requisition--Project Mortgages AGENCY: Office of the Chief Information... Title of Information Collection: Contractor's Requisition--Project Mortgages. OMB Approval Number: 2502...

  4. Cosmology based on f(R) gravity admits 1 eV sterile neutrinos.

    Science.gov (United States)

    Motohashi, Hayato; Starobinsky, Alexei A; Yokoyama, Jun'ichi

    2013-03-22

    It is shown that the tension between recent neutrino oscillation experiments, favoring sterile neutrinos with masses of the order of 1 eV, and cosmological data which impose stringent constraints on neutrino masses from the free streaming suppression of density fluctuations, can be resolved in models of the present accelerated expansion of the Universe based on f(R) gravity.

  5. rBCG30-induced immunity and cross-protection against Mycobacterium leprae challenge are enhanced by boosting with the Mycobacterium tuberculosis 30-kilodalton antigen 85B.

    Science.gov (United States)

    Gillis, Thomas P; Tullius, Michael V; Horwitz, Marcus A

    2014-09-01

    Leprosy remains a major global health problem and typically occurs in regions in which tuberculosis is endemic. Vaccines are needed that protect against both infections and do so better than the suboptimal Mycobacterium bovis BCG vaccine. Here, we evaluated rBCG30, a vaccine previously demonstrated to induce protection superior to that of BCG against Mycobacterium tuberculosis and Mycobacterium bovis challenge in animal models, for efficacy against Mycobacterium leprae challenge in a murine model of leprosy. rBCG30 overexpresses the M. tuberculosis 30-kDa major secretory protein antigen 85B, which is 85% homologous with the M. leprae homolog (r30ML). Mice were sham immunized or immunized intradermally with BCG or rBCG30 and challenged 2.5 months later by injection of viable M. leprae into each hind footpad. After 7 months, vaccine efficacy was assessed by enumerating the M. leprae bacteria per footpad. Both BCG and rBCG30 induced significant protection against M. leprae challenge. In the one experiment in which a comparison between BCG and rBCG30 was feasible, rBCG30 induced significantly greater protection than did BCG. Immunization of mice with purified M. tuberculosis or M. leprae antigen 85B also induced protection against M. leprae challenge but less so than BCG or rBCG30. Notably, boosting rBCG30 with M. tuberculosis antigen 85B significantly enhanced r30ML-specific immune responses, substantially more so than boosting BCG, and significantly augmented protection against M. leprae challenge. Thus, rBCG30, a vaccine that induces improved protection against M. tuberculosis, induces cross-protection against M. leprae that is comparable or potentially superior to that induced by BCG, and boosting rBCG30 with antigen 85B further enhances immune responses and protective efficacy. Copyright © 2014, American Society for Microbiology. All Rights Reserved.

  6. 30 CFR 746.10 - Information collection.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 3 2010-07-01 2010-07-01 false Information collection. 746.10 Section 746.10... LANDS PROGRAM REVIEW AND APPROVAL OF MINING PLANS § 746.10 Information collection. The information... U.S.C. 3507 and assigned clearance number 1029-0026. The information is being collected to determine...

  7. 77 FR 35855 - Safety Zone, Temporary Change for Recurring Fifth Coast Guard District Fireworks Displays...

    Science.gov (United States)

    2012-06-15

    ... 1625-AA00 Safety Zone, Temporary Change for Recurring Fifth Coast Guard District Fireworks Displays; Northwest Harbor (East Channel) and Tred Avon River, MD AGENCY: Coast Guard, DHS. ACTION: Temporary final... Channel), Patapsco River, and Tred Avon River during the event. DATES: This rule is effective from 8 p.m...

  8. USAGE OF PASTE FOR TEMPORARY PLACEMENT IN THE TREATMENT OF CHRONIC APICAL PERIODONTITIS

    Directory of Open Access Journals (Sweden)

    A.V. Borysenko

    2012-03-01

    Full Text Available Summary: The aim of the present investigation was usage of medicamental paste with antibacterial and regeneration action for temporary placement in the treatment of chronic apical periodontitis. Materials and method: The medicamental paste for temporary placement of root canals consists of a mixture of metronidazole, Enterosgel (Silm and Alflutop (Biotehnos S.A., Romania. Thë paste was used for the treatment of 30 teeth with chronic apical periodontitis. Final obturation of the root canals was performed with gutta percha cones and sealer. The efficiency of the treatment was appreciated after examination on the basis of clinical and radiographic findings. Results: During the treatment of the 30 teeth, no exacerbations of the pathological process were recorded. Pain after obturation of the root canals was revealed in only 6 (20% of the treated teeth. No pain, pathologic changes of gingiva, good mastication efficiency in all teeth after treatment were revealed. Conclusions: The high clinical efficiency of the medicamental paste with antibacterial and regeneration action at the level of temporary root canals placement in the treatment of chronic apical periodontitis was shown. Keywords: chronic apical periodontitis, medicamental paste for temporary root canals placement, metronidazole, Enterosgel (Silm and Alflutop (Biotehnos S.A., Romania

  9. Controlling Microstructure of Yttria-Stabilized Zirconia Prepared from Suspensions and Solutions by Plasma Spraying with High Feed Rates.

    Czech Academy of Sciences Publication Activity Database

    Mušálek, Radek; Medřický, Jan; Tesař, Tomáš; Kotlan, Jiří; Pala, Zdeněk; Lukáč, František; Illková, Ksenia; Hlína, Michal; Chráska, Tomáš; Sokołowski, P.; Curry, N.

    2017-01-01

    Roč. 26, č. 8 (2017), s. 1787-1803 ISSN 1059-9630 R&D Projects: GA ČR GA15-12145S Institutional support: RVO:61389021 Keywords : hybrid plasma torch * microstructure * solution * precursor spraying * suspension spraying * thermal barrier * coatings (TBCs) * water-stabilized plasma * yttria-stabilized zirconia (YSZ) Subject RIV: JK - Corrosion ; Surface Treatment of Materials OBOR OECD: Coating and films Impact factor: 1.488, year: 2016 https://link.springer.com/ article /10.1007/s11666-017-0622-x

  10. Development and validation of an HPLC method to quantify camptothecin in polymeric nanocapsule suspensions.

    Science.gov (United States)

    Granada, Andréa; Murakami, Fabio S; Sartori, Tatiane; Lemos-Senna, Elenara; Silva, Marcos A S

    2008-01-01

    A simple, rapid, and sensitive reversed-phase column high-performance liquid chromatographic method was developed and validated to quantify camptothecin (CPT) in polymeric nanocapsule suspensions. The chromatographic separation was performed on a Supelcosil LC-18 column (15 cm x 4.6 mm id, 5 microm) using a mobile phase consisting of methanol-10 mM KH2PO4 (60 + 40, v/v; pH 2.8) at a flow rate of 1.0 mL/min and ultraviolet detection at 254 nm. The calibration graph was linear from 0.5 to 3.0 microg/mL with a correlation coefficient of 0.9979, and the limit of quantitation was 0.35 microg/mL. The assay recovery ranged from 97.3 to 105.0%. The intraday and interday relative standard deviation values were entrapment efficiency and drug content in polymeric nanocapsule suspensions during the early stage of formulation development.

  11. 77 FR 4853 - Onyx Service & Solutions, Inc.; Order of Suspension of Trading

    Science.gov (United States)

    2012-01-31

    ... Suspension of Trading January 27, 2012. It appears to the Securities and Exchange Commission that there is a... the public interest and the protection of investors require a suspension of trading in the securities... Exchange Act of 1934, that trading in the securities of the above-listed company is suspended for the...

  12. 76 FR 12144 - Advanced Optics Electronics, Inc.; Order of Suspension of Trading

    Science.gov (United States)

    2011-03-04

    ... Suspension of Trading March 2, 2011. It appears to the Securities and Exchange Commission that there is a... the opinion that the public interest and the protection of investors require a suspension of trading... Securities Exchange Act of 1934, that trading in the securities of the above-listed company is suspended for...

  13. 77 FR 58203 - Freedom Environmental Services, Inc.; Order of Suspension of Trading

    Science.gov (United States)

    2012-09-19

    ... Suspension of Trading September 17, 2012. It appears to the Securities and Exchange Commission that there is... require a suspension of trading in the securities of the above-listed company. Therefore, it is ordered, pursuant to Section 12(k) of the Securities Exchange Act of 1934, that trading in the securities of the...

  14. 75 FR 36128 - Green Energy Resources, Inc.; Order of Suspension of Trading

    Science.gov (United States)

    2010-06-24

    ... Suspension of Trading June 22, 2010. It appears to the Securities and Exchange Commission that there is a... a suspension of trading in the securities of Green Energy. Therefore, it is ordered, pursuant to Section 12(k) of the Securities Exchange Act of 1934, that trading in the securities of the above-listed...

  15. Temporary employment and health: a review.

    Science.gov (United States)

    Virtanen, Marianna; Kivimäki, Mika; Joensuu, Matti; Virtanen, Pekka; Elovainio, Marko; Vahtera, Jussi

    2005-06-01

    We aimed to review evidence on the relationship between temporary employment and health, and to see whether the association is dependent on outcome measure, instability of employment, and contextual factors. We systematically searched for studies of temporary employment and various health outcomes and critically appraised 27 studies. The review suggests higher psychological morbidity among temporary workers compared with permanent employees. According to some studies, temporary workers also have a higher risk of occupational injuries but their sickness absence is lower. Morbidity may be higher in temporary jobs with high employment instability and in countries with a lower number of temporary workers and unemployed workers. The evidence indicates an association between temporary employment and psychological morbidity. The health risk may depend on instability of temporary employment and the context. Confounding by occupation may have biased some of the studies. Additional research to clarify the role of employment instability, hazard accumulation, and selection is recommended.

  16. A general framework to test gravity using galaxy clusters - I. Modelling the dynamical mass of haloes in f(R) gravity

    Science.gov (United States)

    Mitchell, Myles A.; He, Jian-hua; Arnold, Christian; Li, Baojiu

    2018-06-01

    We propose a new framework for testing gravity using cluster observations, which aims to provide an unbiased constraint on modified gravity models from Sunyaev-Zel'dovich (SZ) and X-ray cluster counts and the cluster gas fraction, among other possible observables. Focusing on a popular f(R) model of gravity, we propose a novel procedure to recalibrate mass scaling relations from Λ cold dark matter (ΛCDM) to f(R) gravity for SZ and X-ray cluster observables. We find that the complicated modified gravity effects can be simply modelled as a dependence on a combination of the background scalar field and redshift, fR(z)/(1 + z), regardless of the f(R) model parameter. By employing a large suite of N-body simulations, we demonstrate that a theoretically derived tanh fitting formula is in excellent agreement with the dynamical mass enhancement of dark matter haloes for a large range of background field parameters and redshifts. Our framework is sufficiently flexible to allow for tests of other models and inclusion of further observables, and the one-parameter description of the dynamical mass enhancement can have important implications on the theoretical modelling of observables and on practical tests of gravity.

  17. 78 FR 33216 - Temporary Change of Dates for Recurring Marine Event in the Fifth Coast Guard District, Mattaponi...

    Science.gov (United States)

    2013-06-04

    ... 1625-AA08 Temporary Change of Dates for Recurring Marine Event in the Fifth Coast Guard District, Mattaponi Drag Boat Race, Mattaponi River; Wakema, VA AGENCY: Coast Guard, DHS. ACTION: Temporary final rule. SUMMARY: The Coast Guard is establishing a temporary change to the enforcement period of special local...

  18. Enhancement of stability of various nZVI suspensions used in groundwater remediation with environmentally friendly organic stabilizers

    Science.gov (United States)

    Schmid, Doris; Wagner, Stephan; Velimirović, Milica; Laumann, Susanne; Micić, Vesna; Hofmann, Thilo

    2014-05-01

    The use of nanoscale zero-valent iron (nZVI) particles for in situ remediation of polluted soil and groundwater has been shown as one of the most promising techniques [1]. The success of this technology depends on the mobility, reactivity, and longevity of nZVI particles. The mobility of nZVI particles depends on the properties of the single particles, stability of the particle suspension, and the aquifer material [1,2]. In order to enhance the mobility of nZVI, the mobility-decisive properties of the nZVI particles in suspension such as concentration, size distribution, surface charge, and sedimentation rate have to be investigated and optimized. Previous studies showed that pristine nZVI particles aggregate rapidly in water, reducing the particles radius of influence after injection [3]. In order to prevent aggregation and sedimentation of the nZVI particles, and consequently improve the stability of nZVI suspension and therefore the mobility of the nZVI particles, surface stabilizers can be used to provide electrostatic repulsion and steric or electrosteric stabilization [3,4]. The objective of this lab-scale study is to investigate the potential for enhancing the stability of different nZVI suspensions by means of environmentally friendly organic stabilizers, including carboxymethyl cellulose, pectin, alginate, xanthan, and guar gum. The different nZVI particles used included pristine and polyacrylic acid-coated nZVI particles provided in suspension (Nanofer 25 and Nanofer 25S, respectively, NANOIRON s.r.o., Czech Republic), air-stable nZVI particles (Nanofer Star, (NANOIRON s.r.o., Czech Republic), and milled iron flakes (UVR-FIA, Germany). In order to study the enhancement of nZVI stability (1 g L-1 total iron) different concentrations of organic stabilizers (1-20 wt.%) were applied in these nZVI suspensions. Each nZVI suspension was freshly prepared and treated for 10 minutes with Ultra-Turrax (15 000 rpm) and 10 minutes ultrasonic bath prior to

  19. Progress report of the Nuclear Physics Department (1.10.1982 - 30.9.1983)

    International Nuclear Information System (INIS)

    1984-04-01

    This progress report presents the experiments and the technological studies carried out at the Nuclear Physics Department of Saclay from October 1, 1982 to September 30, 1983. These studies concern the structure of nuclei and hypernuclei and various reaction mechanisms. They have been performed with the 9 MV tandem Van de Graaff, with the 700 MeV electron linac, at the synchrotron SATURNE, the heavy ion accelerator GANIL, the SARA facility at Grenoble and the secondary beams at CERN [fr

  20. 76 FR 33803 - Order of Suspension of Trading

    Science.gov (United States)

    2011-06-09

    ... SECURITIES AND EXCHANGE COMMISSION [File No. 500-1] Order of Suspension of Trading June 7, 2011... trading in the securities of the above-listed companies. Therefore, it is ordered, pursuant to Section 12(k) of the Securities Exchange Act of 1934, that trading in the securities of the above-listed...

  1. 78 FR 33882 - Order of Suspension of Trading

    Science.gov (United States)

    2013-06-05

    ... SECURITIES AND EXCHANGE COMMISSION [File No. 500-1] Order of Suspension of Trading June 3, 2013... Wi-Tron, Inc. Zone Mining Ltd. It appears to the Securities and Exchange Commission that there is a... Commission that there is a lack of current and accurate information concerning the securities of Zone Mining...

  2. Prime Contract Awards Alphabetically by Contractor, by State or Country, and Place, Fiscal Year 1987. Part 10. Input S R L-Kodensha Company, Ltd.

    Science.gov (United States)

    1987-01-01

    m ZOO 0)- ZmC’o < 1- W -1 000I 1-0NN I00 0 NN000 0 I U l-10 1-� 1-E 13 41Z00000004 .40 1000000a 100000C CA- CAQ 0 /00 GAo - -- 4I 4 4 4 C20 k-.4...N-u o 0 m uc)0000000 - -4- - -j JINI (jrj""j4j" uWr-o.4(.-C--4 C0~0 N (0 JN C ’ C - M C0I- -4----l-.4-4------444- -- - - - - - C) 4-C Q---4- F-0--0

  3. 5 CFR 213.3199 - Temporary organizations.

    Science.gov (United States)

    2010-01-01

    ... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Temporary organizations. 213.3199 Section... SERVICE Excepted Schedules Schedule A § 213.3199 Temporary organizations. Positions on the staffs of temporary organizations, as defined in 5 U.S.C. 3161(a). Appointments may not exceed 3 years, but temporary...

  4. 75 FR 26822 - In the Matter of: Universal Property Development & Acquisition Corp.; Order of Suspension of Trading

    Science.gov (United States)

    2010-05-12

    ... Universal Property Development & Acquisition Corp. (``Universal Property'') because it has not filed any... SECURITIES AND EXCHANGE COMMISSION [File No. 500-1] In the Matter of: Universal Property Development & Acquisition Corp.; Order of Suspension of Trading May 10, 2010. It appears to the Securities and...

  5. Emergence of running dark energy from polynomial f(R) theory in Palatini formalism

    Energy Technology Data Exchange (ETDEWEB)

    Szydlowski, Marek [Jagiellonian University, Astronomical Observatory, Krakow (Poland); Jagiellonian University, Mark Kac Complex Systems Research Centre, Krakow (Poland); Stachowski, Aleksander [Jagiellonian University, Astronomical Observatory, Krakow (Poland); Borowiec, Andrzej [University of Wroclaw, Institute of Theoretical Physics, Wroclaw (Poland)

    2017-09-15

    We consider FRW cosmology in f(R)= R + γR{sup 2} + δR{sup 3} modified framework. The Palatini approach reduces its dynamics to the simple generalization of Friedmann equation. Thus we study the dynamics in two-dimensional phase space with some details. After reformulation of the model in the Einstein frame, it reduces to the FRW cosmological model with a homogeneous scalar field and vanishing kinetic energy term. This potential determines the running cosmological constant term as a function of the Ricci scalar. As a result we obtain the emergent dark energy parametrization from the covariant theory. We study also singularities of the model and demonstrate that in the Einstein frame some undesirable singularities disappear. (orig.)

  6. Alexandru Popa, Untersuchungen zu den römisch-barbarischen Kontakten Östlich der römischen Provinz Dacia Antiquitatis reihe 3 Abhnadlungen zur vor-und frühgeschichte, zur klassichen und provinzial-römischen archäologie und zur geschichte des altertum

    Directory of Open Access Journals (Sweden)

    Vasile Iarmulschi

    2016-06-01

    Full Text Available Review on book - Alexandru Popa, Untersuchungen zu den römisch-barbarischen Kontakten Östlich der römischen Provinz Dacia Antiquitatis reihe 3 Abhnadlungen zur vor-und frühgeschichte, zur klassichen und provinzial-römischen archäologie und zur geschichte des altertum

  7. 75 FR 6883 - Temporary Agricultural Employment of H-2A Aliens in the United States

    Science.gov (United States)

    2010-02-12

    ... Division 29 CFR Part 501 Temporary Agricultural Employment of H-2A Aliens in the United States; Final Rule... Division 29 CFR Part 501 RIN 1205-AB55 Temporary Agricultural Employment of H-2A Aliens in the United... of the alien in such labor or services will not adversely affect the wages and working conditions of...

  8. Analysis of an industrial production suspension of Bacillus lentus subtilisin crystals by powder diffraction: a powerful quality-control tool.

    Science.gov (United States)

    Frankaer, Christian G; Moroz, Olga V; Turkenburg, Johan P; Aspmo, Stein I; Thymark, Majbritt; Friis, Esben P; Stahl, Kenny; Nielsen, Jens E; Wilson, Keith S; Harris, Pernille

    2014-04-01

    A microcrystalline suspension of Bacillus lentus subtilisin (Savinase) produced during industrial large-scale production was analysed by X-ray powder diffraction (XRPD) and X-ray single-crystal diffraction (MX). XRPD established that the bulk microcrystal sample representative of the entire production suspension corresponded to space group P212121, with unit-cell parameters a = 47.65, b = 62.43, c = 75.74 Å, equivalent to those for a known orthorhombic crystal form (PDB entry 1ndq). MX using synchrotron beamlines at the Diamond Light Source with beam dimensions of 20 × 20 µm was subsequently used to study the largest crystals present in the suspension, with diffraction data being collected from two single crystals (∼20 × 20 × 60 µm) to resolutions of 1.40 and 1.57 Å, respectively. Both structures also belonged to space group P2(1)2(1)2(1), but were quite distinct from the dominant form identified by XRPD, with unit-cell parameters a = 53.04, b = 57.55, c = 71.37 Å and a = 52.72, b = 57.13, c = 65.86 Å, respectively, and refined to R = 10.8% and Rfree = 15.5% and to R = 14.1% and Rfree = 18.0%, respectively. They are also different from any of the forms previously reported in the PDB. A controlled crystallization experiment with a highly purified Savinase sample allowed the growth of single crystals of the form identified by XRPD; their structure was solved and refined to a resolution of 1.17 Å with an R of 9.2% and an Rfree of 11.8%. Thus, there are at least three polymorphs present in the production suspension, albeit with the 1ndq-like microcrystals predominating. It is shown how the two techniques can provide invaluable and complementary information for such a production suspension and it is proposed that XRPD provides an excellent quality-control tool for such suspensions.

  9. Spherical thin shells in F(R) gravity. Construction and stability

    Energy Technology Data Exchange (ETDEWEB)

    Eiroa, Ernesto F. [Instituto de Astronomia y Fisica del Espacio (IAFE, CONICET-UBA), Buenos Aires (Argentina); Universidad de Buenos Aires, Departamento de Fisica, Facultad de Ciencias Exactas y Naturales, Buenos Aires (Argentina); Figueroa Aguirre, Griselda [Instituto de Astronomia y Fisica del Espacio (IAFE, CONICET-UBA), Buenos Aires (Argentina)

    2018-01-15

    We present a broad class of spherical thin shells of matter in F(R) gravity. We show that the corresponding junction conditions determine the equation of state between the energy density and the pressure/tension at the surface. We analyze the stability of the static configurations under perturbations preserving the symmetry. We apply the formalism to the construction of charged bubbles and we find that there exist stable static configurations for a suitable set of the parameters of the model. (orig.)

  10. Spherical thin shells in F(R) gravity. Construction and stability

    International Nuclear Information System (INIS)

    Eiroa, Ernesto F.; Figueroa Aguirre, Griselda

    2018-01-01

    We present a broad class of spherical thin shells of matter in F(R) gravity. We show that the corresponding junction conditions determine the equation of state between the energy density and the pressure/tension at the surface. We analyze the stability of the static configurations under perturbations preserving the symmetry. We apply the formalism to the construction of charged bubbles and we find that there exist stable static configurations for a suitable set of the parameters of the model. (orig.)

  11. 10 CFR 905.30 - Purpose and applicability.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 4 2010-01-01 2010-01-01 false Purpose and applicability. 905.30 Section 905.30 Energy DEPARTMENT OF ENERGY ENERGY PLANNING AND MANAGEMENT PROGRAM Power Marketing Initiative § 905.30 Purpose and applicability. (a) The Power Marketing Initiative (PMI) provides a framework for marketing Western's long-term...

  12. High-frequency attenuation and backscatter measurements of rat blood between 30 and 60 MHz

    International Nuclear Information System (INIS)

    Huang, Chih-Chung

    2010-01-01

    There has recently been a great deal of interest in noninvasive high-frequency ultrasound imaging of small animals such as rats due to their being the preferred animal model for gene therapy and cancer research. Improving the interpretation of the obtained images and furthering the development of the imaging devices require a detailed knowledge of the ultrasound attenuation and backscattering of biological tissue (e.g. blood) at high frequencies. In the present study, the attenuation and backscattering coefficients of the rat red blood cell (RBC) suspensions and whole blood with hematocrits ranging from 6% to 40% were measured between 30 and 60 MHz using a modified substitution approach. The acoustic parameters of porcine blood under the same conditions were also measured in order to compare differences in the blood properties between these two animals. For porcine blood, both whole blood and RBC suspension were stirred at a rotation speed of 200 rpm. Three different rotation speeds of 100, 200 and 300 rpm were carried out for rat blood experiments. The attenuation coefficients of both rat and porcine blood were found to increase linearly with frequency and hematocrit (the values of coefficients of determination (r 2 ) are around 0.82-0.97 for all cases). The average attenuation coefficient of rat whole blood with a hematocrit of 40% increased from 0.26 Nepers mm -1 at 30 MHz to 0.47 Nepers mm -1 at 60 MHz. The maximum backscattering coefficients of both rat and porcine RBC suspensions were between 10% and 15% hematocrits at all frequencies. The fourth-power dependence of backscatter on frequency was approximately valid for rat RBC suspensions with hematocrits between 6% and 40%. However, the frequency dependence of the backscatter estimate deviates from a fourth-power law for porcine RBC suspension with hematocrit higher than 20%. The backscattering coefficient plateaued for hematocrits higher than 15% in porcine blood, but for rat blood it was maximal around a

  13. 78 FR 9010 - Dental Devices; Reclassification of Temporary Mandibular Condyle Prosthesis

    Science.gov (United States)

    2013-02-07

    .... FDA-2012-N-1239] Dental Devices; Reclassification of Temporary Mandibular Condyle Prosthesis AGENCY... condyle prostheses into class III, based on the recommendation of a Dental Products Panel (the Panel... Administration, Dental Products Advisory Panel Meeting Transcript, February 12, 1997; http://www.accessdata.fda...

  14. MiR-30a-5p suppresses tumor growth in colon carcinoma by targeting DTL

    DEFF Research Database (Denmark)

    Baraniskin, Alexander; Birkenkamp-Demtröder, Karin; Maghnouj, Abdelouahid

    2012-01-01

    MicroRNAs (miRNAs) are small non-coding RNAs that are involved in different biological processes by suppressing target gene expression. Altered expression of miR-30a-5p has been reported in colon carcinoma. To elucidate its potential biological role in colon cancer, miR-30a-5p was overexpressed via...... with in silico miRNA target prediction, we identified the denticleless protein homolog (DTL) as a potential miRNA-30a-5p target. Subsequent reporter gene assays confirmed the predicted miR-30a-5p binding site in the 3'untranslated region of DTL. Importantly, overexpression of DTL in HCT116 cells partially...... is frequently overexpressed in colorectal cancer. Thus, our data suggest that restoring miR-30a-5p function may prove useful as therapeutic strategy for tumors with reduced miR-30a-5p expression....

  15. Modeling aerosol suspension from soils and oceans as sources of micropollutants to air.

    Science.gov (United States)

    Qureshi, Asif; MacLeod, Matthew; Hungerbühler, Konrad

    2009-10-01

    Soil and marine aerosol suspension are two physical mass transfer processes that are not usually included in models describing fate and transport of environmental pollutants. Here, we review the literature on soil and marine aerosol suspension and estimate aerosol suspension mass transfer velocities for inclusion in multimedia models, as a global average and on a 1 x 1 scale. The yearly, global average mass transfer velocity for soil aerosol suspension is estimated to be 6 x 10(-10)mh(-1), approximately an order of magnitude smaller than marine aerosol suspension, which is estimated to be 8 x 10(-9)mh(-1). Monthly averages of these velocities can be as high as 10(-7)mh(-1) and 10(-5)mh(-1) for soil and marine aerosol suspension, respectively, depending on location. We use a unit-world multimedia model to analyze the relevance of these two suspension processes as a mechanism that enhances long-range atmospheric transport of pollutants. This is done by monitoring a metric of long-range transport potential, phi-one thousand (phi1000), that denotes the fraction of modeled emissions to air, water or soil in a source region that reaches a distance of 1000 km in air. We find that when the yearly, globally averaged mass transfer velocity is used, marine aerosol suspension increases phi1000 only fractionally for both emissions to air and water. However, enrichment of substances in marine aerosols, or speciation between ionic and neutral forms in ocean water may increase the influence of this surface-to-air transfer process. Soil aerosol suspension can be the dominant process for soil-to-air transfer in an emission-to-soil scenario for certain substances that have a high affinity to soil. When a suspension mass transfer velocity near the maximum limit is used, soil suspension remains important if the emissions are made to soil, and marine aerosol suspension becomes important regardless of if emissions are made to air or water compartments. We recommend that multimedia models

  16. 30 CFR 700.10 - Information collection.

    Science.gov (United States)

    2010-07-01

    ... longer a surface coal mining and reclamation operation and thereby when regulatory jurisdiction may end... 30 Mineral Resources 3 2010-07-01 2010-07-01 false Information collection. 700.10 Section 700.10 Mineral Resources OFFICE OF SURFACE MINING RECLAMATION AND ENFORCEMENT, DEPARTMENT OF THE INTERIOR GENERAL...

  17. The Temporary Leave Dilemma -

    DEFF Research Database (Denmark)

    Amilon, Anna

    2010-01-01

    Lone mothers have to take care of a sick child with little or no help from the child’s other parent and have to carry all costs connected to leave-taking. This paper empirically tests whether lone mothers take more temporary parental leave to care for sick children than partnered mothers...... and whether parental leave is associated with a signaling cost. The results from this study of Swedish mothers show that lone mothers use more temporary parental leave than partnered mothers. Further, within the group of lone mothers, those with higher socioeconomic status take less temporary parental leave...... than those with lower socioeconomic status, whereas no such differences are found within the group of partnered mothers. One possible interpretation is that signaling costs negatively influence the utilization of temporary parental leave for lone mothers....

  18. Cosmology based on f(R) gravity with O(1) eV sterile neutrino

    Energy Technology Data Exchange (ETDEWEB)

    Chudaykin, Anton S.; Gorbunov, Dmitry S. [Institute for Nuclear Research of the Russian Academy of Sciences, 60th October Anniversary prospect 7a, Moscow 117312 (Russian Federation); Starobinsky, Alexei A. [L.D. Landau Institute for Theoretical Physics of the Russian Academy of Sciences, Moscow 119334 (Russian Federation); Burenin, Rodion A., E-mail: chudy@ms2.inr.ac.ru, E-mail: gorby@ms2.inr.ac.ru, E-mail: alstar@landau.ac.ru, E-mail: rodion@hea.iki.rssi.ru [Space Research Institute of the Russian Academy of Sciences (IKI), Moscow, ul. Profsoyuznaya, 84/32, 117997 (Russian Federation)

    2015-05-01

    We address the cosmological role of an additional O(1) eV sterile neutrino in modified gravity models. We confront the present cosmological data with predictions of the FLRW cosmological model based on a variant of f(R) modified gravity proposed by one of the authors previously. This viable cosmological model which deviation from general relativity with a cosmological constant Λ decreases as R{sup −2n} for large, but not too large values of the Ricci scalar R (while no Λ is introduced by hand at small R) provides an alternative explanation of present dark energy and the accelerated expansion of the Universe (the case n=2 is considered in the paper). Various up-to-date cosmological data sets exploited include measurements of the cosmic microwave background (CMB) anisotropy, the CMB lensing potential, the baryon acoustic oscillations (BAO), the cluster mass function and the Hubble constant. We find that the CMB+BAO constraints strongly restrict the sum of neutrino masses from above. This excludes values of the model parameter λ∼ 1 for which distinctive cosmological features of the model are mostly pronounced as compared to the ΛCDM model, since then free streaming damping of perturbations due to neutrino rest masses is not sufficient to compensate their extra growth occurring in f(R) modified gravity. Thus, in the gravity sector we obtain λ>8.2 (2σ) with the account of systematic uncertainties in galaxy cluster mass function measurements and λ>9.4 (2σ) without them. At the same time in the latter case we find for the sterile neutrino mass 0.47 eV < m{sub ν, sterile} < 1 eV (2σ) assuming that the sterile neutrinos are thermalized and the active neutrinos are massless, not significantly larger than in the standard ΛCDM with the same data set: 0.45 eV < m{sub ν, sterile} < 0.92 eV (2σ). However, a possible discovery of a sterile neutrino with the mass m{sub ν, sterile} ≈ 1.5 eV motivated by various anomalies in neutrino oscillation

  19. 77 FR 47915 - Wheego Electric Cars, Inc.; Grant of Petition for Temporary Exemption From the Electronic...

    Science.gov (United States)

    2012-08-10

    ...-0013] Wheego Electric Cars, Inc.; Grant of Petition for Temporary Exemption From the Electronic.... SUMMARY: This notice grants the petition of Wheego Electric Cars, Inc. (Wheego) for the temporary... procedures in 49 CFR part 555, Wheego Electric Cars, Inc. (Wheego) submitted a petition dated August 15, 2011...

  20. 77 FR 31183 - Safety Zone, Temporary Change for Recurring Fireworks Display Within the Fifth Coast Guard...

    Science.gov (United States)

    2012-05-25

    ...-AA00 Safety Zone, Temporary Change for Recurring Fireworks Display Within the Fifth Coast Guard District, Pamlico River and Tar River; Washington, NC AGENCY: Coast Guard, DHS. ACTION: Temporary final... is intended to restrict vessel traffic in a portion of the Pamlico River and Tar River near...

  1. 10 CFR 30.2 - Resolution of conflict.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 1 2010-01-01 2010-01-01 false Resolution of conflict. 30.2 Section 30.2 Energy NUCLEAR... Provisions § 30.2 Resolution of conflict. The requirements of this part are in addition to, and not in substitution for, other requirements of this chapter. In any conflict between the requirements in this part and...

  2. Effect of concentration on the rheology and serum separation of tomato suspensions

    NARCIS (Netherlands)

    Ouden, den F.W.C.; Vliet, van T.

    2002-01-01

    The °Brix value of the tomato concentrate, from which tomato suspensions were prepared, was shown to have a large effect on the resulting apparent viscosity and storage modulus. The apparent viscosity of a tomato suspension prepared from a 30 °Brix tomato concentrate was only 35␘f that of a

  3. Culture de suspensions cellulaires embryogéniques et régénération en plantules par embryogenèse somatique chez le bananier et le bananier plantain Musa spp

    Directory of Open Access Journals (Sweden)

    Dhed'a, D.

    1992-01-01

    Full Text Available Embryogenie cell suspension and plant regeneration through somatic embryogenesis in bananas and plantains Musa spp. Embryogenie cell suspensions have been initiated using explants from meristematic shoot-tips (scalps. The culture medium has been a modified Murashige and Skoog medium supplemented, according to the steps of culture, with 5fiM 2, 4-D, 1-10//M BAPorzeatin. The suspensions obtained for 5 banana varieties have regenerated plants through somatic embryogenesis. Embryogenie cell suspensions have proved to be the material of choice for cryopreservation, protoplast isolation and culture and for genetic manipulation of Musa for resistance to diseases.

  4. Digitala spel : En kvalitativ studie om E-sportspelares erfarenheter från karriär och upplevd hälsa

    OpenAIRE

    Szilagyi, Ivan

    2017-01-01

    Ungdomar och unga vuxna är de främsta användarna av digitala spel och även de främsta entusiasterna av fenomenet E-sport. Spelvanor är av betydelse då studier har påvisat att det finns determinanter, både fysiologiska och psykologiska som kan påverka individens välbefinnande.Syftet med studien var att undersöka professionella E-sportspelares erfarenheter av att utöva sin sport och hur de upplever att detta påverkar hälsan. En kvalitativ metod användes och datainsamling utfördes genom intervju...

  5. Detection of interference phase by digital computation of quadrature signals in homodyne laser interferometry

    Czech Academy of Sciences Publication Activity Database

    Řeřucha, Šimon; Buchta, Zdeněk; Šarbort, Martin; Lazar, Josef; Číp, Ondřej

    2012-01-01

    Roč. 12, č. 10 (2012), s. 14095-14112 ISSN 1424-8220 R&D Projects: GA ČR GAP102/10/1813; GA MŠk ED0017/01/01; GA MPO FR-TI2/705; GA MPO FR-TI1/241; GA MŠk EE2.3.30.0054 Institutional support: RVO:68081731 Keywords : digital signal processing * homodyne detection * laser interferometry * optical metrology Subject RIV: BH - Optics, Masers, Lasers Impact factor: 1.953, year: 2012

  6. Explosion i rötkammare med biogas

    DEFF Research Database (Denmark)

    Hedlund, Frank Huess

    2017-01-01

    En biogasreaktor exploderade 1990 på Vejle Centrala reningsverk. Nu, 24 år senare, när biogas är populärare än någonsin, har händelsen helt försvunnit från tillgängliga, öppna källor......En biogasreaktor exploderade 1990 på Vejle Centrala reningsverk. Nu, 24 år senare, när biogas är populärare än någonsin, har händelsen helt försvunnit från tillgängliga, öppna källor...

  7. 77 FR 4623 - Wheego Electric Cars, Inc. Receipt of Petition for Temporary Exemption From the Electronic...

    Science.gov (United States)

    2012-01-30

    ...-0013] Wheego Electric Cars, Inc. Receipt of Petition for Temporary Exemption From the Electronic.... SUMMARY: In accordance with the procedures in 49 CFR part 555, Wheego Electric Cars, Inc., has petitioned... Electric Cars, Inc. (Wheego) submitted a petition dated August 15, 2011 asking the agency for a temporary...

  8. 76 FR 35508 - Alabama Southern Railroad, L.L.C.-Temporary Trackage Rights Exemption-Norfolk Southern Railway...

    Science.gov (United States)

    2011-06-17

    ... Railroad, L.L.C.--Temporary Trackage Rights Exemption--Norfolk Southern Railway Company Norfolk Southern... grant nonexclusive overhead temporary trackage rights to Alabama Southern Railroad, L.L.C. (ABS) over a... http://www.stb.dot.gov . Decided: June 13, 2011. By the Board. Rachel D. Campbell, Director, Office of...

  9. 76 FR 60124 - Tesla Motors, Inc.; Grant of Petition for Temporary Exemption From the Electronic Stability...

    Science.gov (United States)

    2011-09-28

    ...-0110] Tesla Motors, Inc.; Grant of Petition for Temporary Exemption From the Electronic Stability... notice grants the petition of Tesla Motors, Inc. (Tesla) for the temporary exemption of its Roadster... procedures in 49 CFR Part 555, Tesla Motors, Inc. (Tesla) submitted a petition dated June 7, 2011 asking the...

  10. Q ‑ Φ criticality and microstructure of charged AdS black holes in f(R) gravity

    Science.gov (United States)

    Deng, Gao-Ming; Huang, Yong-Chang

    2017-12-01

    The phase transition and critical behaviors of charged AdS black holes in f(R) gravity with a conformally invariant Maxwell (CIM) source and constant curvature are further investigated. As a highlight, this research is carried out by employing new state parameters (T,Q, Φ) and contributes to deeper understanding of the thermodynamics and phase structure of black holes. Our analyses manifest that the charged f(R)-CIM AdS black hole undergoes a first-order small-large black hole phase transition, and the critical behaviors qualitatively behave like a Van der Waals liquid-vapor system. However, differing from the case in Einstein’s gravity, phase structures of the black holes in f(R) theory exhibit an interesting dependence on gravity modification parameters. Moreover, we adopt the thermodynamic geometry to probe the black hole microscopic properties. The results show that, on the one hand, both the Ruppeiner curvature and heat capacity diverge exactly at the critical point, on the other hand, the f(R)-CIM AdS black hole possesses the property as ideal Fermi gases. Of special interest, we discover a microscopic similarity between the black holes and a Van der Waals liquid-vapor system.

  11. The coordinated roles of miR-26a and miR-30c in regulating TGFβ1-induced epithelial-to-mesenchymal transition in diabetic nephropathy

    DEFF Research Database (Denmark)

    Zheng, Zongji; Guan, Meiping; Jia, Yijie

    2016-01-01

    and miR-30c targeted connective tissue growth factor (CTGF); additionally, Snail family zinc finger 1 (Snail1), a potent epithelial-to-mesenchymal transition (EMT) inducer, was targeted by miR-30c. Overexpression of miR-26a and miR-30c coordinately decreased CTGF protein levels and subsequently...

  12. The use of bead beating to prepare suspensions of nuclei for flow cytometry from fresh leaves, herbarium leaves, petals and pollen.

    Science.gov (United States)

    Roberts, Andy V

    2007-12-01

    "Bead beating" is commonly used to release DNA from cells for genomic studies but it was used here to prepare suspensions of plant nuclei for measurement of DNA amounts by flow cytometry. Plant material was placed in 2-ml screw-capped tubes containing beads of zirconia/silica (2.5 mm diameter) or glass (2.5 or 1.0 mm diameter) and 1 ml of lysis buffer. The tubes were mechanically shaken with an FP120 FastPrep Cell Disrupter to release intact nuclei from plant tissue by the impact of the beads. The nuclei were then stained with propidium iodide (PI) and analyzed by flow cytometry. The method was tested using fresh leaves, fresh petals and herbarium leaves of Rosa canina, leaves and pollen of R. rugosa, and fresh leaves of Petroselinum crispum, Nicotiana tabacum, and Allium cepa. Batches of 12 samples of fresh leaves were prepared, simultaneously, in 45 s by bead beating in the Cell Disrupter. In flow cytometry histograms, nuclei of fresh leaves gave G(1)/G(0) peaks with CVs of less than 3.0% and nuclei from fresh petals and herbarium leaves of R. canina, and pollen of the generative nuclei of R. rugosa gave peaks with coefficients of variation (CVs) of less than 4.0%. DNA amounts estimated from 24-month-old herbarium leaves, using P. crispum as an internal standard, were less than those of fresh leaves by a small but significant amount. Suspensions of nuclei can be prepared rapidly and conveniently from a diversity of tissues by bead beating. Exposure of laboratory workers to harmful substances in the lysis buffer is minimized. (c) 2007 International Society for Analytical Cytology

  13. Colonic transit time in patient with slow-transit constipation: Comparison of radiopaque markers and barium suspension method

    Energy Technology Data Exchange (ETDEWEB)

    Xu Huimin [Department of General Surgery, Beijing Chaoyang Hospital, Capital Medical University, No. 8 Gongtina Lu, Chaoyang District, Beijing 100020 (China); Department of General Surgery, Weifang People' s Hospital, ShanDong Province 261041 (China); Han Jiagang [Department of General Surgery, Beijing Chaoyang Hospital, Capital Medical University, No. 8 Gongtina Lu, Chaoyang District, Beijing 100020 (China); Na Ying [Department of Medical Imaging, Weifang People' s Hospital, ShanDong Province 261041 (China); Zhao Bo; Ma Huachong [Department of General Surgery, Beijing Chaoyang Hospital, Capital Medical University, No. 8 Gongtina Lu, Chaoyang District, Beijing 100020 (China); Wang Zhenjun, E-mail: wang3zj@sohu.com [Department of General Surgery, Beijing Chaoyang Hospital, Capital Medical University, No. 8 Gongtina Lu, Chaoyang District, Beijing 100020 (China)

    2011-08-15

    Background: Colonic transit study provides valuable information before surgical treatment is considered for patient with constipation. The radiopaque markers method is the most common way for evaluating colon transit time. The aim of this study is to compare the barium suspension with the radiopaque makers to assess the colonic mobility in patient with constipation. Methods: Colonic transit time was measured in 11 female patients with slow-transit constipation using both radiopaque markers and barium suspension method. In radiopaque markers method, the patient ingested 20 markers on the first day, and an abdominal radiograph was performed every 24 h until 80% markers were excreted. In barium suspension method, the patient swallowed up to 50 ml of 200% (w/v) barium meal. The abdominal radiographs were taken at the same time point as the former. Results: The total or segmental colonic transit time were obviously prolonged in all patients. Segmental transits time spent in the right colon, left colon and rectosigmoid for radiopaque markers and barium suspension method was, respectively, 30 {+-} 6 h and 34 {+-} 7 h; 38 {+-} 9 h and 32 {+-} 6 h; 40 {+-} 8 h and 38 {+-} 10 h. In the radiopaque markers method, total colonic transit time was 108 {+-} 14 h and it was 103 {+-} 13 h in the barium suspension method (P > 0.05). Conclusion: The barium suspension and radiopaque markers gave the similar results for colonic transit time. The barium suspension was a simple and cheap method for evaluating the colonic mobility.

  14. 40 CFR 35.2105 - Debarment and suspension.

    Science.gov (United States)

    2010-07-01

    ... unit of government for facilities planning or design work whose name appears on the master list of... applicant should be found non-responsible under part 30 of this subchapter or be the subject of possible debarment or suspension under part 32 of this subchapter. ...

  15. Disentangling the f(R)-duality

    Energy Technology Data Exchange (ETDEWEB)

    Broy, Benedict J.; Westphal, Alexander [Deutsches Elektronen-Synchrotron DESY, Theory Group, Hamburg, 22603 Germany (Germany); Pedro, Francisco G., E-mail: benedict.broy@desy.de, E-mail: francisco.pedro@desy.de, E-mail: alexander.westphal@desy.de [Departamento de Física Teórica and Instituto de Física Teórica UAM-CSIC, Universidad Autónoma de Madrid, Cantoblanco, Madrid, 28049 Spain (Spain)

    2015-03-01

    Motivated by UV realisations of Starobinsky-like inflation models, we study generic exponential plateau-like potentials to understand whether an exact f(R)-formulation may still be obtained when the asymptotic shift-symmetry of the potential is broken for larger field values. Potentials which break the shift symmetry with rising exponentials at large field values only allow for corresponding f(R)-descriptions with a leading order term R{sup n} with 1R{sup 2}-term survives as part of a series expansion of the function f(R) and thus cannot maintain a plateau for all field values. We further find a lean and instructive way to obtain a function f(R) describing m{sup 2}φ{sup 2}-inflation which breaks the shift symmetry with a monomial, and corresponds to effectively logarithmic corrections to an R+R{sup 2} model. These examples emphasise that higher order terms in f(R)-theory may not be neglected if they are present at all. Additionally, we relate the function f(R) corresponding to chaotic inflation to a more general Jordan frame set-up. In addition, we consider f(R)-duals of two given UV examples, both from supergravity and string theory. Finally, we outline the CMB phenomenology of these models which show effects of power suppression at low-ℓ.

  16. Disentangling the f(R)-duality

    Energy Technology Data Exchange (ETDEWEB)

    Broy, Benedict J. [Deutsches Elektronen-Synchrotron DESY, Theory Group, Hamburg, 22603 (Germany); Pedro, Francisco G. [Departamento de Física Teórica and Instituto de Física Teórica UAM-CSIC, Universidad Autónoma de Madrid, Cantoblanco, Madrid, 28049 (Spain); Westphal, Alexander [Deutsches Elektronen-Synchrotron DESY, Theory Group, Hamburg, 22603 (Germany)

    2015-03-16

    Motivated by UV realisations of Starobinsky-like inflation models, we study generic exponential plateau-like potentials to understand whether an exact f(R)-formulation may still be obtained when the asymptotic shift-symmetry of the potential is broken for larger field values. Potentials which break the shift symmetry with rising exponentials at large field values only allow for corresponding f(R)-descriptions with a leading order term R{sup n} with 1R{sup 2}-term survives as part of a series expansion of the function f(R) and thus cannot maintain a plateau for all field values. We further find a lean and instructive way to obtain a function f(R) describing m{sup 2}ϕ{sup 2}-inflation which breaks the shift symmetry with a monomial, and corresponds to effectively logarithmic corrections to an R+R{sup 2} model. These examples emphasise that higher order terms in f(R)-theory may not be neglected if they are present at all. Additionally, we relate the function f(R) corresponding to chaotic inflation to a more general Jordan frame set-up. In addition, we consider f(R)-duals of two given UV examples, both from supergravity and string theory. Finally, we outline the CMB phenomenology of these models which show effects of power suppression at low-ℓ.

  17. Inkjet printable nanosilver suspensions for enhanced sintering quality in rapid manufacturing

    International Nuclear Information System (INIS)

    Bai, John G; Creehan, Kevin D; Kuhn, Howard A

    2007-01-01

    Inkjet printable nanosilver suspensions were prepared by dispersing 30 nm silver particles into a water-based binder system to enhance the sintering quality in rapid manufacturing. During three-dimensional printing (3DP), the nanosilver suspensions were inkjet printed onto repetitively spread microsilver powder for selective joining. Since the nanosilver particles in the suspensions can be sintered at relatively low temperatures to bond the neighbouring microsilver powder, they were used to provide the continuous bonding strength of the manufacturing parts during the heat-up procedure of the sintering operation. Comparative study shows that the silver parts printed using the nanosilver suspension were significantly enhanced in sintering quality than those printed using the binder system, especially when the silver parts had thin or small features with high aspect ratios

  18. Fracture in Kaolinite clay suspensions

    Science.gov (United States)

    Kosgodagan Acharige, Sebastien; Jerolmack, Douglas J.; Arratia, Paulo E.

    2017-11-01

    Clay minerals are involved in many natural (landslides, river channels) and industrial processes (ceramics, cosmetics, oil recovery). They are plate shaped charged colloids and exhibit different flow properties than simpler colloids when suspended in a liquid such as thixotropy and shear-banding. kaolinite platelets are non-swelling, meaning that the stacks formed by the platelets do not have water layers, and thus the suspension does not have a sol-gel transition. However, it has been shown that kaolinite suspensions possesses a non-zero yield stress even at low concentrations, indicating that the particles arrange themselves in a structure through attractive interactions. Here, we experimentally investigate the sedimentation of kaolinite suspensions in a Hele-Shaw cell. The sedimentation of these dilute suspensions can display solid behavior like fracture, revealed in cross-polarized light, which is linked to the failure of the weakly-bonded structure (typical yield stress 10-2 Pa). By changing the interaction potential of the particles (by sonication or introducing salts), we show through these sedimentation experiments, how the fracture pattern can be avoided. Research was sponsored by the Army Research Laboratory and was accomplished under Grant Number 569074.

  19. 77 FR 14417 - Notice of Temporary Closure on Public Lands in Gooding and Elmore Counties, ID

    Science.gov (United States)

    2012-03-09

    ...] Notice of Temporary Closure on Public Lands in Gooding and Elmore Counties, ID AGENCY: Bureau of Land Management, Interior. ACTION: Notice of temporary closure. SUMMARY: Notice is hereby given that the Blair Fire closure to motorized vehicle use is in effect on public lands administered by the Four Rivers and...

  20. 77 FR 28764 - Temporary Non-agricultural Employment of H-2B Aliens in the United States

    Science.gov (United States)

    2012-05-16

    ... DEPARTMENT OF LABOR Employment and Training Administration 20 CFR Part 655 RIN 1205-AB58 Temporary Non-agricultural Employment of H-2B Aliens in the United States AGENCY: Employment and Training... Temporary Non-agricultural Employment of H-2B Aliens in the United States, published February 21, 2012 (the...

  1. 78 FR 79308 - Dental Devices; Reclassification of Temporary Mandibular Condyle Prosthesis

    Science.gov (United States)

    2013-12-30

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration 21 CFR Part 872 [Docket No. FDA-2012-N-1239] Dental Devices; Reclassification of Temporary Mandibular Condyle Prosthesis AGENCY... delegated to the Commissioner of Food and Drugs, 21 CFR part 872 is amended as follows: PART 872--DENTAL...

  2. 7 CFR 29.3052 - Red color (R).

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Red color (R). 29.3052 Section 29.3052 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing... Red color (R). A brownish red. [24 FR 8771, Oct. 29, 1959. Redesignated at 47 FR 51722, Nov. 17, 1982...

  3. Mirror suspension system for the TAMA SAS

    CERN Document Server

    Takamori, A; Bertolini, A; Cella, G; DeSalvo, R; Fukushima, M; Iida, Y; Jacquier, F; Kawamura, S; Marka, S; Nishi, Y; Numata, K; Sannibale, V; Somiya, K; Takahashi, R; Tariq, H; Tsubono, K; Ugas, J; Viboud, N; Yamamoto, H; Yoda, T; Wang Chen Yang

    2002-01-01

    Several R and D programmes are ongoing to develop the next generation of interferometric gravitational wave detectors providing the superior sensitivity desired for refined astronomical observations. In order to obtain a wide observation band at low frequencies, the optics need to be isolated from the seismic noise. The TAMA SAS (seismic attenuation system) has been developed within an international collaboration between TAMA, LIGO, and some European institutes, with the main objective of achieving sufficient low-frequency seismic attenuation (-180 dB at 10 HZ). The system suppresses seismic noise well below the other noise levels starting at very low frequencies above 10 Hz. It also includes an active inertial damping system to decrease the residual motion of the optics enough to allow a stable operation of the interferometer. The TAMA SAS also comprises a sophisticated mirror suspension subsystem (SUS). The SUS provides support for the optics and vibration isolation complementing the SAS performance. The SU...

  4. Connectivity percolation in suspensions of attractive square-well spherocylinders.

    Science.gov (United States)

    Dixit, Mohit; Meyer, Hugues; Schilling, Tanja

    2016-01-01

    We have studied the connectivity percolation transition in suspensions of attractive square-well spherocylinders by means of Monte Carlo simulation and connectedness percolation theory. In the 1980s the percolation threshold of slender fibers has been predicted to scale as the fibers' inverse aspect ratio [Phys. Rev. B 30, 3933 (1984)PRBMDO1098-012110.1103/PhysRevB.30.3933]. The main finding of our study is that the attractive spherocylinder system reaches this inverse scaling regime at much lower aspect ratios than found in suspensions of hard spherocylinders. We explain this difference by showing that third virial corrections of the pair connectedness functions, which are responsible for the deviation from the scaling regime, are less important for attractive potentials than for hard particles.

  5. 78 FR 66040 - 30-Day Notice of Proposed Information Collection: HUD-Owned Real Estate-Sales Contract and Addendums

    Science.gov (United States)

    2013-11-04

    ... DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT [Docket No. FR-5683-N-91] 30-Day Notice of Proposed Information Collection: HUD-Owned Real Estate--Sales Contract and Addendums AGENCY: Office of the Chief... published a 30 day notice of proposed information collection entitled HUD-Owned Real Estate-Sales Contract...

  6. rTMS of the dorsomedial prefrontal cortex for major depression: safety, tolerability, effectiveness, and outcome predictors for 10 Hz versus intermittent theta-burst stimulation.

    Science.gov (United States)

    Bakker, Nathan; Shahab, Saba; Giacobbe, Peter; Blumberger, Daniel M; Daskalakis, Zafiris J; Kennedy, Sidney H; Downar, Jonathan

    2015-01-01

    Conventional rTMS protocols for major depression commonly employ stimulation sessions lasting >30 min. However, recent studies have sought to improve costs, capacities, and outcomes by employing briefer protocols such as theta burst stimulation (iTBS). To compare safety, effectiveness, and outcome predictors for DMPFC-rTMS with 10 Hz (30 min) versus iTBS (6 min) protocols, in a large, naturalistic, retrospective case series. A chart review identified 185 patients with a medication-resistant major depressive episode who underwent 20-30 sessions of DMPFC-rTMS (10 Hz, n = 98; iTBS, n = 87) at a single Canadian clinic from 2011 to 2014. Clinical characteristics of 10 Hz and iTBS patients did not differ prior to treatment, aside from significantly higher age in iTBS patients. A total 7912 runs of DMPFC-rTMS (10 Hz, 4274; iTBS, 3638) were administered, without any seizures or other serious adverse events, and no significant differences in rates of premature discontinuation between groups. Dichotomous outcomes did not differ significantly between groups (Response/remission rates: Beck Depression Inventory-II: 10 Hz, 40.6%/29.2%; iTBS, 43.0%/31.0%. 17-item Hamilton Rating Scale for Depression: 10 Hz, 50.6%/38.5%; iTBS, 48.5%/27.9%). On continuous outcomes, there was no significant difference between groups in pre-treatment or post-treatment scores, or percent improvement on either measure. Mixed-effects modeling revealed no significant group-by-time interaction on either measure. Both 10 Hz and iTBS DMPFC-rTMS appear safe and tolerable at 120% resting motor threshold. The effectiveness of 6 min iTBS and 30 min 10 Hz protocols appears comparable. Randomized trials comparing 10 Hz to iTBS may be warranted. Copyright © 2015 The Authors. Published by Elsevier Inc. All rights reserved.

  7. Shear-induced particle migration in suspensions of rods

    Energy Technology Data Exchange (ETDEWEB)

    Mondy, L.A. (Sandia National Laboratories, Albuquerque, New Mexico 87185 (United States)); Brenner, H. (Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139 (United States)); Altobelli, S.A. (The Lovelace Institutes, 2425 Ridgecrest Drive, S. E., Albuquerque, New Mexico 87108 (United States)); Abbott, J.R.; Graham, A.L. (Los Alamos National Laboratory, Los Alamos, New Mexico 87545 (United States))

    1994-03-01

    Shear-induced migration of particles occurs in suspensions of neutrally buoyant spheres in Newtonian fluids undergoing shear in the annular space between two rotating, coaxial cylinders (a wide-gap Couette), even when the suspension is in creeping flow. Previous studies have shown that the rate of migration of spherical particles from the high-shear-rate region near the inner (rotating) cylinder to the low-shear-rate region near the outer (stationary) cylinder increases rapidly with increasing sphere size. To determine the effect of particle shape, the migration of rods suspended in Newtonian fluids was recently measured. The behavior of several suspensions was studied. Each suspension contained well-characterized, uniform rods with aspect ratios ranging from 2 to 18 at either 0.30 or 0.40 volume fraction. At the same volume fraction of solids, the steady-state, radial concentration profiles for rods were independent of aspect ratio and were indistinguishable from those obtained from suspended spheres. Only minor differences near the walls (attributable to the finite size of the rods relative to the curvature of the walls) appeared to differentiate the profiles. Data taken during the transition from a well-mixed suspension to the final steady state show that the rate of migration increased as the volume of the individual rods increased.

  8. f(R) global monopole revisited

    Energy Technology Data Exchange (ETDEWEB)

    Carames, Thiago R.P.; Fabris, Julio C.; Belich, H. [Universidade Federal do Espirito Santo (UFES), Vitoria, ES (Brazil); Bezerra de Mello, E.R. [Universidade Federal da Paraiba, Departamento de Fisica, Joao Pessoa, PB (Brazil)

    2017-07-15

    In this paper the f(R) global monopole is reexamined. We provide an exact solution for the modified field equations in the presence of a global monopole for regions outside its core, generalizing previous results. Additionally, we discuss some particular cases obtained from this solution. We consider a setup consisting of a possible Schwarzschild black hole that absorbs the topological defect, giving rise to a static black hole endowed with a monopole's charge. Besides, we demonstrate how the asymptotic behavior of the Higgs field far from the monopole's core is shaped by a class of spacetime metrics which includes the ones analyzed here. In order to assess the gravitational properties of this system, we analyze the geodesic motion of both massive and massless test particles moving in the vicinity of such configuration. For the material particles we set the requirements they have to obey in order to experience stable orbits. On the other hand, for the photons we investigate how their trajectories are affected by the gravitational field of this black hole. (orig.)

  9. Inactivation of viruses in platelet suspensions that retain their in vitro characteristics: Comparison of psoralen-ultraviolet A and merocyanine 540-visible light methods

    International Nuclear Information System (INIS)

    Dodd, R.Y.; Moroff, G.; Wagner, S.; Dabay, M.H.; Dorfman, E.; George, V.; Ribeiro, A.; Shumaker, J.; Benade, L.E.

    1991-01-01

    The ability of two fundamentally different photochemical procedures to inactivate model viruses in platelet suspensions was compared. Merocyanine 540 (MC 540) with visible light was used as an example of an oxygen-dependent chemical-directed at the viral membrane, and aminomethyl trimethyl psoralen (AMT) with ultraviolet A light (UVA) was used as an example of a nucleic acid-directed system. Antiviral conditions in petri dishes were identified and the effects of these procedures on platelet suspensions in plastic storage containers were studied. Concentrations of photochemicals in the 10 to 150 mumol range with 30 to 60 minutes of visible light (MC 540) or 1 to 2 minutes of UVA (AMT) readily inactivated 5 to 6 log10 of vesicular stomatitis virus (VSV) and other model viruses in platelet suspensions, provided the plasma concentration was reduced to about 15 percent by the use of a synthetic platelet storage medium. Extracellular pH, morphology scores, and aggregation response dropped markedly when platelets were treated with MC 540 and visible light. However, treatment with 136 mumol per L of AMT and 1 to 3 minutes of UVA could inactivate 5 log10 of VSV in platelet suspensions with retention of platelet characteristics for 4 days, particularly if oxygen levels were reduced during treatment. These studies demonstrate that AMT-UVA treatment meets the initial requirements for virus inactivation in platelet suspensions

  10. 30 CFR 817.43 - Diversions.

    Science.gov (United States)

    2010-07-01

    ... the peak runoff of a 10-year, 6-hour precipitation event for a temporary diversion and a 100-year, 6-hour precipitation event for a permanent diversion. (4) A permanent stream-channel diversion or a... runoff of a 2-year, 6-hour precipitation event for a temporary diversion and a 10-year, 6-hour...

  11. 77 FR 36305 - Stream Communications Network & Media, Inc.; Order of Suspension of Trading

    Science.gov (United States)

    2012-06-18

    ....; Order of Suspension of Trading June 14, 2012. It appears to the Securities and Exchange Commission that... a suspension of trading in the securities of the above-listed company. Therefore, it is ordered, pursuant to Section 12(k) of the Securities Exchange Act of 1934, that trading in the security of the above...

  12. 78 FR 20960 - Face Up Entertainment Group, Inc.; Order of Suspension of Trading

    Science.gov (United States)

    2013-04-08

    ... Suspension of Trading April 4, 2013. It appears to the Securities and Exchange Commission that there is a... business operations, and trading in its securities. Face Up is a Florida corporation based in Valley Stream... interest and the protection of investors require a suspension of trading in the securities of the above...

  13. 46 CFR 76.30-10 - Location and spacing of tubing.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 3 2010-10-01 2010-10-01 false Location and spacing of tubing. 76.30-10 Section 76.30... PROTECTION EQUIPMENT Pneumatic Fire Detecting System, Details § 76.30-10 Location and spacing of tubing. (a) The tubing shall be located on the overhead or within 12 inches of the overhead on the bulkheads...

  14. 75 FR 23571 - Airworthiness Directives; McDonnell Douglas Corporation Model DC-10-10, DC-10-10F, DC-10-15, DC...

    Science.gov (United States)

    2010-05-04

    ... Airworthiness Directives; McDonnell Douglas Corporation Model DC- 10-10, DC-10-10F, DC-10-15, DC-10-30, DC-10... amends Sec. 39.13 by adding the following new AD: 2010-09-12 McDonnell Douglas Corporation: Amendment 39... to McDonnell Douglas Corporation Model DC- 10-10, DC-10-10F, DC-10-15, DC-10-30, DC-10-30F (KC-10A...

  15. Branded prescription drug fee. Final regulations, temporary regulations, and removal of temporary regulations.

    Science.gov (United States)

    2014-07-28

    This document contains final regulations that provide guidance on the annual fee imposed on covered entities engaged in the business of manufacturing or importing branded prescription drugs. This fee was enacted by section 9008 of the Patient Protection and Affordable Care Act, as amended by section 1404 of the Health Care and Education Reconciliation Act of 2010. This document also withdraws the Branded Prescription Drug Fee temporary regulations and contains new temporary regulations regarding the definition of controlled group that apply beginning on January 1, 2015. The final regulations and the new temporary regulations affect persons engaged in the business of manufacturing or importing certain branded prescription drugs. The text of the temporary regulations in this document also serves as the text of proposed regulations set forth in a notice of proposed rulemaking (REG-123286-14) on this subject in the Proposed Rules section in this issue of the Federal Register.

  16. Employment protection and temporary work agencies

    OpenAIRE

    Baumann, Florian; Mechtel, Mario; Stähler, Nikolai

    2008-01-01

    Employers who use temporary agency staff in contrast to regular staff are not affected by employment protection regulations when terminating a job. Therefore, services provided by temporary work agencies may be seen as a substitute for regular employment. In this paper, we analyze the effects of employment protection on the size of the temporary work agency sector in a model of equilibrium unemployment. We find that higher firing costs may even reduce temporary work agency employment if agenc...

  17. ScatterJn: An ImageJ Plugin for Scatterplot-Matrix Analysis and Classification of Spatially Resolved Analytical Microscopy Data

    Directory of Open Access Journals (Sweden)

    Fabian Zeitvogel

    2016-02-01

    Full Text Available We present ScatterJn, an ImageJ (and Fiji plugin for scatterplot-based exploration and analysis of analytical microscopy data. In contrast to commonly used scatterplot tools, it handles more than two input images (or image stacks, respectively by creating a matrix of pairwise scatterplots. The tool offers the possibility to manually classify pixels by selecting regions of datapoints in the scatterplots as well as in the spatial domain. We demonstrate its functioning using a set of elemental maps acquired by SEM-EDX mapping of a soil sample. The plugin is available at https://savannah.nongnu.org/projects/scatterjn.

  18. Etude de l'heterogeneite des suspensions newtoniennes de ...

    African Journals Online (AJOL)

    Dans le présent papier nous exposons les résultats d'une étude expérimentale des suspensions newtoniennes de « grosses sphères dures » (diamètre moyen = 4,4 mm) à l'aide des profils de vitesses. Cette étude est ménée en vue de répondre aux préoccupations des industriels du secteur agro-alimentaire qui mettent ...

  19. Stability of an extemporaneously compounded minoxidil oral suspension.

    Science.gov (United States)

    Song, Yunmei; Chin, Zen Whey; Ellis, David; Lwin, Ei Mon Phyo; Turner, Sean; Williams, Desmond; Garg, Sanjay

    2018-03-01

    Results of a study to determine the stability of an extemporaneously compounded minoxidil oral suspension under various temperature and stress conditions are reported. Commercially available minoxidil tablets (10 mg) were crushed to a fine powder, and predetermined amounts of 2 suspending vehicles were added to produce a 1-mg/mL suspension, which was stored in glass bottles at room temperature (25 ± 2 °C) or in a refrigerator (4 ± 2 °C). To simulate daily patient use, 5 days weekly 1 bottle of the suspension was removed from refrigerated storage and shaken and 0.5 mL of the contents discarded. At each specified time point, samples were analyzed in duplicate ( n = 6 for each test condition) using a validated high-performance liquid chromatography method. Samples were visually observed and their pH measured at each time point. Microbiological studies were performed on day 0 and at week 24. The mean percentage of initial minoxidil concentration remaining in all refrigerated samples exceeded 90% throughout the 24-week study, with no change in appearance, pH, microbial activity, odor, or redispersibility. During storage at room temperature, the suspension exhibited a color change at week 4, with slight sedimentation after 6 weeks, although minoxidil recovery exceeded 90% for 10 weeks. An extemporaneously compounded minoxidil oral suspension was stable for 24 weeks when stored in a refrigerator. This suspension can be used for up to 3 weeks when stored at room temperature. Copyright © 2018 by the American Society of Health-System Pharmacists, Inc. All rights reserved.

  20. 78 FR 12106 - Debarment, Suspension, and Ineligibility of Contractors

    Science.gov (United States)

    2013-02-21

    ... include a recommendation by the SDC as to a proposed course of action; (2) The debarment decision-making... proposed debarment; (3) The suspension decision-making process, which shall afford the contractor (and any... Management, Contracting; Attention: Contracting Policy, 1900 E Street NW., Washington, DC 20415; or email...

  1. The temporary international collective chronicle

    International Nuclear Information System (INIS)

    Kravchenko, Yu.Ya.

    2007-01-01

    The temporary international collective brief history is presented from the time of its establishment in 1972 (and even earlier) till the termination of its activity in 1990 (and even later). Works in the temporary international collective framework demonstrate an example of successful cooperation of specialists from different countries in the field of calculation-theoretical and experimental research on the WWER reactor physics. The results of experimental and calculation studies were reported to the topical meetings, workshops, conferences, and symposia as well as were published in the temporary international collective reports and proceedings. The answers to the questions about the temporary international collective activity-What? Where? When?-are presented in this chronicle (Authors)

  2. 75 FR 43039 - Fresh Prunes Grown in Designated Counties in Washington and in Umatilla County, OR; Suspension of...

    Science.gov (United States)

    2010-07-23

    ... marketing of fresh prunes over the past four years. Based on its analysis, the Committee has determined that... DEPARTMENT OF AGRICULTURE Agricultural Marketing Service 7 CFR Part 924 [Doc. No. AMS-FV-10-0054...; Suspension of Reporting and Assessment Requirements AGENCY: Agricultural Marketing Service, USDA. ACTION...

  3. 77 FR 28305 - Temporary Rule To Delay Start Date of 2012-2013 South Atlantic Black Sea Bass Commercial Fishing...

    Science.gov (United States)

    2012-05-14

    .... 120501426-2426-01] RIN 0648-BB98 Temporary Rule To Delay Start Date of 2012-2013 South Atlantic Black Sea... this temporary rule to delay the start date of the 2012-2013 fishing season for the commercial black... temporary rule delays the start date of the 2012-2013 commercial fishing season for black sea bass from June...

  4. Ecoulement et mise en structure de suspensions macroscopiques

    Science.gov (United States)

    Petit, L.

    In this review, we report the various experimental studies performed on suspensions of solid particules in liquids, and concerning the rheological behaviour of such systems and the ordering of particules under the applied velocity fields. The number of materials which are flowing suspensions (reagents in chemical engineering, paints while spreading, blood flow, muds in oil reservoir) gave rise to a number of experimental studies, especially in the last twenty years. The results show a wide variety of behaviour, even for systems of intermediate concentration. In addition, even for identical systems, the results depend of the type of flow. Then, it is clear that, in addition of the standard parameters which are to be taken into account, it is necessary to consider the type of flow the suspension is submitted to. The flow influences the spatial distribution of the particules, leading to their ordering or migration. These ordering or motions influence the flow, and then, the rheological behaviour of the whole system. So, there is a feedback mechanism from the ordering to the flow, which explains the experimental observations. Nous reportons dans cette revue les différentes études expérimentales réalisées sur les suspensions de particules solides dans un liquide et qui concernent le comportement rhéologique de ces systèmes ainsi que les mouvements des particules sous l'effet des champs de vitesse imposés. Ces mouvements peuvent conduire soit à des mises en structure, ou encore à des migrations des particules. L'importance du nombre de matériaux qui se présentent sous forme de suspension et qui sont mis en écoulement (réactif en génie chimique, peintures lors de leur mise en place, écoulement sanguin, boues dans les forages pétroliers,...) a motivé un grand nombre de travaux expérimentaux plus fondamentaux sur le sujet, particulièrement dans les vingt dernières années. Les résultats correspondants montrent une très grande diversité des

  5. General f(R and conformal inflation from minimal supergravity plus matter

    Directory of Open Access Journals (Sweden)

    Horatiu Nastase

    2016-02-01

    Full Text Available We embed general f(R inflationary models in minimal supergravity plus matter, a single chiral superfield Φ, with or without another superfield S, via a Jordan frame Einstein+scalar description. In particular, inflationary models like a generalized Starobinsky one are analyzed and constraints on them are found. We also embed the related models of conformal inflation, also described as Jordan frame Einstein+scalar models, in particular the conformal inflation from the Higgs model, and analyze the inflationary constraints on them.

  6. 78 FR 30914 - Grand River Dam Authority Notice of Application for Temporary Variance of License and Soliciting...

    Science.gov (United States)

    2013-05-23

    .... Description of Request: Grand River Dam Authority (GRDA) requests a temporary variance, for the year 2013, to... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Project No. 1494-416] Grand River Dam Authority Notice of Application for Temporary Variance of License and Soliciting Comments, Motions To...

  7. Quality of life in a randomized trial of early closure of temporary ileostomy after rectal resection for cancer (EASY trial)

    DEFF Research Database (Denmark)

    Park, J; Danielsen, A K; Angenete, E

    2018-01-01

    BACKGROUND: A temporary ileostomy may reduce symptoms from anastomotic leakage after rectal cancer resection. Earlier results of the EASY trial showed that early closure of the temporary ileostomy was associated with significantly fewer postoperative complications. The aim of the present study...... was to compare health-related quality of life (HRQOL) following early versus late closure of a temporary ileostomy. METHODS: Early closure of a temporary ileostomy (at 8-13 days) was compared with late closure (at more than 12 weeks) in a multicentre RCT (EASY) that included patients who underwent rectal...... after resection using the European Organisation for Research and Treatment of Cancer (EORTC) questionnaires QLQ-C30 and QLQ-CR29 and Short Form 36 (SF-36®). RESULTS: There were 112 patients available for analysis. Response rates of the questionnaires were 82-95 per cent, except for EORTC QLQ-C30 at 12...

  8. 77 FR 59244 - Agency Information Collection Activities; Extension of Currently-Approved Information Collection...

    Science.gov (United States)

    2012-09-26

    ... September 30, 1998 (63 FR 52192). Pursuant to this authority, the BTS, now part of the Research and... transferred the responsibility for the F&OS program from BTS to FMCSA (69 FR 51009). On August 10, 2006 (71 FR... financial and statistical reporting regulations of BTS formerly located in chapter XI of title 49 CFR to...

  9. Voltammetry of metallic powder suspensions on mercury electrodes

    Czech Academy of Sciences Publication Activity Database

    Korshunov, A.; Heyrovský, Michael

    2006-01-01

    Roč. 18, č. 4 (2006), s. 423-426 ISSN 1040-0397 R&D Projects: GA MPO 1H-PK/42 Institutional research plan: CEZ:AV0Z40400503 Keywords : metallic particles * oxide layers * suspensions * mercury electrodes * particulate electrolysis Subject RIV: CG - Electrochemistry Impact factor: 2.444, year: 2006

  10. 78 FR 23316 - The Royal Bank of Scotland plc, et al.; Notice of Application and Temporary Order

    Science.gov (United States)

    2013-04-18

    ... plc, et al.; Notice of Application and Temporary Order April 12, 2013. AGENCY: Securities and Exchange Commission (``Commission''). ACTION: Temporary order and notice of application for a permanent order under... application for a permanent order. Applicants have also applied for a permanent order. APPLICANTS: The Royal...

  11. 76 FR 16447 - ETHICON, a Subsidiary of Johnson & Johnson Including On-Site Leased Workers From Kelly Temporary...

    Science.gov (United States)

    2011-03-23

    ... workers of ETHICON, A Johnson and Johnson Company, San Angelo, Texas, separated from employment on or... Johnson & Johnson Including On-Site Leased Workers From Kelly Temporary Services, San Angelo, TX; Amended... of ETHICON, a subsidiary of Johnson & Johnson, including on-site leased workers from Kelly Temporary...

  12. 32 CFR 147.31 - Temporary eligibility for access at the top secret levels and temporary eligibility for “Q...

    Science.gov (United States)

    2010-07-01

    ... Guidelines for Temporary Access § 147.31 Temporary eligibility for access at the top secret levels and... 32 National Defense 1 2010-07-01 2010-07-01 false Temporary eligibility for access at the top secret levels and temporary eligibility for âQâ access authorization: For someone who is the subject of a...

  13. Konstrukce dřevěného rámu pro oblasti s častým výskytem zemětřesení

    Czech Academy of Sciences Publication Activity Database

    Pospíšil, Stanislav; Drdácký, Miloš; Kasal, Bohumil

    2007-01-01

    Roč. 9, č. 5 (2007), s. 54-57 ISSN 1213-0311 R&D Projects: GA ČR(CZ) GA103/01/0708 Grant - others:evropská komise(XE) ICA1-CT-2000-70013 Institutional research plan: CEZ:AV0Z20710524 Source of funding: R - rámcový projekt EK Keywords : earthquake * timber frames * frequency Subject RIV: JN - Civil Engineering

  14. Colonic transit time in patient with slow-transit constipation: Comparison of radiopaque markers and barium suspension method

    International Nuclear Information System (INIS)

    Xu Huimin; Han Jiagang; Na Ying; Zhao Bo; Ma Huachong; Wang Zhenjun

    2011-01-01

    Background: Colonic transit study provides valuable information before surgical treatment is considered for patient with constipation. The radiopaque markers method is the most common way for evaluating colon transit time. The aim of this study is to compare the barium suspension with the radiopaque makers to assess the colonic mobility in patient with constipation. Methods: Colonic transit time was measured in 11 female patients with slow-transit constipation using both radiopaque markers and barium suspension method. In radiopaque markers method, the patient ingested 20 markers on the first day, and an abdominal radiograph was performed every 24 h until 80% markers were excreted. In barium suspension method, the patient swallowed up to 50 ml of 200% (w/v) barium meal. The abdominal radiographs were taken at the same time point as the former. Results: The total or segmental colonic transit time were obviously prolonged in all patients. Segmental transits time spent in the right colon, left colon and rectosigmoid for radiopaque markers and barium suspension method was, respectively, 30 ± 6 h and 34 ± 7 h; 38 ± 9 h and 32 ± 6 h; 40 ± 8 h and 38 ± 10 h. In the radiopaque markers method, total colonic transit time was 108 ± 14 h and it was 103 ± 13 h in the barium suspension method (P > 0.05). Conclusion: The barium suspension and radiopaque markers gave the similar results for colonic transit time. The barium suspension was a simple and cheap method for evaluating the colonic mobility.

  15. Solcellsparkeringen : En jämförande fallstudie för elbilar och bensinbilar

    OpenAIRE

    Myrén Andersson, Isac; Yttermyr-Sütt, Frans

    2017-01-01

    Av Sveriges totala växthusgasutsläpp är det i nuläget transportsektorn som stårr den största andelen och stårr mer än 30 % av alla utsläpp. Med ett ökande fordonsbestånd och ett fortsatt behov av transporter blir lösningar som minskar utsläppen från denna sektor avgörande för Sveriges hållbara utveckling. Eftersom 93 % av Sveriges drygt 4,7 miljoner personbilar drivs av fossila bränslen skulle investeringar i alternativa färdmedel såsom elbilar kunna leda Sverige i rätt riktning. Förfat...

  16. In vitro multiplication of plantain cv. ‘INIVIT PV-2011’ (Musa AAB) in Temporary Immersion System

    OpenAIRE

    Milagros Basail Pérez; Victor Medero Vega; Yenisey Gutiérrez Sánchez

    2015-01-01

    The work was developed in the laboratory of Plant Biotechnology at Instituto de Investigaciones de Viandas Tropicales (INIVIT) with the aim of multiplying the plantain cultivar ‘INIVIT PV-2011’ (Musa AAB) in Temporary Immersion Systems (10.0 liters Nalgene bottles). The effect of immersion time (10, 20 and 30 minutes), the frequency of immersion (three, six and eight hours), the volume of culture medium per explant (20, 40, 60 and 80 ml), subculture time (15, 18, 21 and 25 days) and the inocu...

  17. 32 CFR 147.32 - Temporary eligibility for access at the top secret and SCI levels and temporary eligibility for...

    Science.gov (United States)

    2010-07-01

    ... Guidelines for Temporary Access § 147.32 Temporary eligibility for access at the top secret and SCI levels... 32 National Defense 1 2010-07-01 2010-07-01 false Temporary eligibility for access at the top secret and SCI levels and temporary eligibility for âQâ access authorization: For someone who is not the...

  18. Finger-like voids induced by viscous fingering during phase inversion of alumina/PES/NMP suspensions

    KAUST Repository

    Wang, Bo; Lai, Zhiping

    2012-01-01

    membrane structure without such finger-like macrovoids was observed when the suspension was slowly immersed into pure ethanol or a mixture of 70. wt% NMP and 30. wt% water, whereas finger-like macrovoids occurred when the suspension was slid into the non

  19. Constraining models of f(R) gravity with Planck and WiggleZ power spectrum data

    Science.gov (United States)

    Dossett, Jason; Hu, Bin; Parkinson, David

    2014-03-01

    In order to explain cosmic acceleration without invoking ``dark'' physics, we consider f(R) modified gravity models, which replace the standard Einstein-Hilbert action in General Relativity with a higher derivative theory. We use data from the WiggleZ Dark Energy survey to probe the formation of structure on large scales which can place tight constraints on these models. We combine the large-scale structure data with measurements of the cosmic microwave background from the Planck surveyor. After parameterizing the modification of the action using the Compton wavelength parameter B0, we constrain this parameter using ISiTGR, assuming an initial non-informative log prior probability distribution of this cross-over scale. We find that the addition of the WiggleZ power spectrum provides the tightest constraints to date on B0 by an order of magnitude, giving log10(B0) explanation.

  20. 36 CFR 13.182 - Temporary facilities.

    Science.gov (United States)

    2010-07-01

    ... 36 Parks, Forests, and Public Property 1 2010-07-01 2010-07-01 false Temporary facilities. 13.182... NATIONAL PARK SYSTEM UNITS IN ALASKA Cabins Use of Temporary Facilities Related to Taking Fish and Wildlife § 13.182 Temporary facilities. In a national preserve where the taking of fish and wildlife is...

  1. Analysis of the yielding behavior of electrorheological suspensions by controlled shear stress experiments

    Czech Academy of Sciences Publication Activity Database

    Pavlínek, V.; Sáha, P.; Perez-Gonzales, K.; de Vargas, L.; Stejskal, Jaroslav; Quadrat, Otakar

    2006-01-01

    Roč. 16, 1-2 (2006), s. 14-18 ISSN 1430-6395 R&D Projects: GA ČR GA202/06/0419 Institutional research plan: CEZ:AV0Z40500505 Keywords : electrorheology * yield stress * suspensions * polyaniline Subject RIV: CD - Macromolecular Chemistry

  2. Standard Review Plan for the review of financial assurance mechanisms for decommissioning under 10 CFR Parts 30, 40, 70, and 72

    International Nuclear Information System (INIS)

    1989-08-01

    Standard Review Plan (SRP) for the Review of Financial Assurance Mechanisms for Decommissioning under 10 CFR Parts 30, 40, 70 and 72, is prepared for the guidance of Nuclear Regulatory Commission staff reviewers in performing reviews of applications from material licensees affected by the decommissioning regulations established June 27, 1988 (53FR24018). The principal purpose of the SRP is to assure the quality and uniformity of staff reviews and to present a base from which to evaluate the financial assurance aspects of the applications. The SRP identifies who performs the review, the matters that are reviewed, the basis for the review, how the review is performed, and the conclusions that are sought

  3. Clean Coal Technology III: 10 MW Demonstration of Gas Suspension Absorption final project performance and economics report

    Energy Technology Data Exchange (ETDEWEB)

    Hsu, F.E.

    1995-08-01

    The 10 MW Demonstration of the Gas Suspension Absorption (GSA) program is a government and industry co-funded technology development. The objective of the project is to demonstrate the performance of the GSA system in treating a 10 MW slipstream of flue gas resulting from the combustion of a high sulfur coal. This project involves design, fabrication, construction and testing of the GSA system. The Project Performance and Economics Report provides the nonproprietary information for the ``10 MW Demonstration of the Gas Suspension Absorption (GSA) Project`` installed at Tennessee Valley Authority`s (TVA) Shawnee Power Station, Center for Emissions Research (CER) at Paducah, Kentucky. The program demonstrated that the GSA flue-gas-desulfurization (FGD) technology is capable of achieving high SO{sub 2} removal efficiencies (greater than 90%), while maintaining particulate emissions below the New Source Performance Standards (NSPS), without any negative environmental impact (section 6). A 28-day test demonstrated the reliability and operability of the GSA system during continuous operation. The test results and detailed discussions of the test data can be obtained from TVA`s Final Report (Appendix A). The Air Toxics Report (Appendix B), prepared by Energy and Environmental Research Corporation (EERC) characterizes air toxic emissions of selected hazardous air pollutants (HAP) from the GSA process. The results of this testing show that the GSA system can substantially reduce the emission of these HAP. With its lower capital costs and maintenance costs (section 7), as compared to conventional semi-dry scrubbers, the GSA technology commands a high potential for further commercialization in the United States. For detailed information refer to The Economic Evaluation Report (Appendix C) prepared by Raytheon Engineers and Constructors.

  4. Cosmological wheel of time: A classical perspective of f(R) gravity

    Science.gov (United States)

    Yadav, Bal Krishna; Verma, Murli Manohar

    It is shown that the structures in the universe can be interpreted to show a closed wheel of time, rather than a straight arrow. An analysis in f(R) gravity model has been carried out to show that due to local observations, a small arc at any given spacetime point would invariably indicate an arrow of time from past to future, though on a quantum scale it is not a linear flow but a closed loop, a fact that can be examined through future observations.

  5. Inference about density and temporary emigration in unmarked populations

    Science.gov (United States)

    Chandler, Richard B.; Royle, J. Andrew; King, David I.

    2011-01-01

    Few species are distributed uniformly in space, and populations of mobile organisms are rarely closed with respect to movement, yet many models of density rely upon these assumptions. We present a hierarchical model allowing inference about the density of unmarked populations subject to temporary emigration and imperfect detection. The model can be fit to data collected using a variety of standard survey methods such as repeated point counts in which removal sampling, double-observer sampling, or distance sampling is used during each count. Simulation studies demonstrated that parameter estimators are unbiased when temporary emigration is either "completely random" or is determined by the size and location of home ranges relative to survey points. We also applied the model to repeated removal sampling data collected on Chestnut-sided Warblers (Dendroica pensylvancia) in the White Mountain National Forest, USA. The density estimate from our model, 1.09 birds/ha, was similar to an estimate of 1.11 birds/ha produced by an intensive spot-mapping effort. Our model is also applicable when processes other than temporary emigration affect the probability of being available for detection, such as in studies using cue counts. Functions to implement the model have been added to the R package unmarked.

  6. Characterization of alumina suspensions by electroacoustics

    Energy Technology Data Exchange (ETDEWEB)

    Galassi, C.; Roncari, E.; Greenwood, R.; Piancastelli, A. [CNR, Faenza (Italy). Research Inst. for Ceramics Technology

    1997-12-31

    Using the acoustophoresis technique three different dispersants were selected to investigate the effect of the volume fraction of the suspension on the minimum amount of dispersant required to give the maximum zeta potential. No effect was detected over a volume fraction range 0.11 to 0.35. The acoustosizer was used to screen many dispersants for alumina in a relatively short time. From the viewpoint that the most stable suspensions are those with the greatest zeta potentials, then the following dispersants can be recommended: Reotan LA (0.25 mg/m{sup 2}) Dolapix CA (0.20 mg/m{sup 2}) and Dolapix PC33 (0.30 mg/m{sup 2}). Vanisperse and Borresperse are poor. Polyacrylic acid and polymethacrylic acid were better than some commercially available products. (orig.) 2 refs.

  7. 78 FR 4788 - Regulated Navigation Area; Reporting Requirements for Barges Loaded With Certain Dangerous...

    Science.gov (United States)

    2013-01-23

    ... Act (APA) (5 U.S.C. 553(b)). This provision authorizes an agency to issue a rule without prior notice... restriction may be made effective less than 30 days after publication. This temporary final rule, suspending... conditions. 33 CFR 165.10; Commandant Instruction Manual M16704.3A, 1-6. The purpose of this temporary final...

  8. 76 FR 7898 - Wheego Electric Cars, Inc.; Grant of Application for Temporary Exemption From Advanced Air Bag...

    Science.gov (United States)

    2011-02-11

    ...-0118] Wheego Electric Cars, Inc.; Grant of Application for Temporary Exemption From Advanced Air Bag... grants the petition of Wheego Electric Cars, Inc. (Wheego) for the temporary exemption of its Whip LiFe... manufacturer of a plug-in electric car. The stated basis of the petition was that requiring compliance would...

  9. Bianchi type-I universe in f(R, T) modified gravity with quark matter and Λ

    Science.gov (United States)

    Ćaǧlar, Halife; Aygün, Sezgin

    2017-02-01

    In this study, we investigate homogeneous and anisotropic Bianchi type I universe in the presence of quark matter source in f(R, T) gravity (Harko et al. in Phys. Rev. D 84:024020, 2011) with cosmological constant Λ (where R is the Ricci scalar and T is the trace of the energy momentum tensor). For this aim we have used the anisotropy feature of Bianchi type I universe and equation of states (EoS) of quark matter. We explore the exact solution f(R,T)=R+2f(T) model for Bianchi type I universe model. When t→∞, we get very small cosmological constant value, this result agrees with recent observations.

  10. Action of 50 R X-ray doses on the breeding function of C3H strain mice - effect of splitting the dose, action of repeated irradiations on successive generations

    International Nuclear Information System (INIS)

    Alix, D.

    1965-01-01

    X-rays exposure effect was studied on C3H strain mice, at the standpoint of the effects produced on breeding function. The method used with this purpose was the following: single doses 20 - 30 - 40 and 50 R/dose, fractional doses: 50 R/total dose, divided in 2 - 5 - 10 or 25 irradiations distributed in one month duration. The offsprings were irradiated at the same doses than the parents, consanguinity being maintained. Statistical treatment of results was carried out, that led at the following conclusions: 1) Couples receiving single exposure of 50 R or two exposures of 25 R at one month interval give comparable results. Fractional doses do not involve the slightest diminution of X-rays effect. 2) 30 R exposure brings about a decrease in fertility, with an increase in abortions. Fertility of 20 R irradiated couples remains below controls. 3) After ten times 5 R and twenty-five 2 R, the number of abortions is the largest. Ovarian function is particularly sensitive to X-rays; one may think that twenty-five 2 R give injuries conditioning non-viability of conception products, smaller doses should produce mutations and yield births of altered genotype individuals. (author) [fr

  11. Temporary labour contracts

    CERN Document Server

    1999-01-01

    The five contracts for Temporary Labour assignments on the CERN site (L020/PE, L021/PE, L022/PE, L023/PE and L024/PE) approved by the Finance Committee in March 1996 (CERN/FC/3857) will reach the end of their initial three-year contractual period at the end of December 1999. Following the satisfactory execution of these contracts during this period, CERN requests approval to extend them from January 2000 for the first of the two years foreseen in the original adjudication. The Finance Committee is invited: - to take note that the three-year expenditure for Temporary Labour contracts from 1997 to 1999 will not exceed 19 100 000 Swiss francs, compared to the 18 900 000 Swiss francs estimated at the time of the adjudication in March 1996; - to approve an extension of the present Temporary Labour contracts for the year 2000 for a total amount not exceeding 6 000 000 Swiss francs.

  12. 78 FR 1872 - Extension and Redesignation of Sudan for Temporary Protected Status

    Science.gov (United States)

    2013-01-09

    ... Hybrid Mission in Darfur USCIS--U.S. Citizenship and Immigration Services What is Temporary Protected... by violent conflicts in four distinct areas: Darfur and the three transitional areas along the Sudan-South Sudan border (Abyei, Blue Nile State, and Southern Kordofan). In some areas of Darfur, Government...

  13. 77 FR 62185 - Temporary Rule Regarding Principal Trades With Certain Advisory Clients

    Science.gov (United States)

    2012-10-12

    ... 3235-AJ96 Temporary Rule Regarding Principal Trades With Certain Advisory Clients AGENCY: Securities... principal capacity in transactions with certain of their advisory clients. The amendment would extend the... Advisers Act when they act in a principal capacity in transactions with certain of their advisory clients...

  14. 75 FR 75650 - Temporary Rule Regarding Principal Trades With Certain Advisory Clients

    Science.gov (United States)

    2010-12-06

    ... 3235-AJ96 Temporary Rule Regarding Principal Trades With Certain Advisory Clients AGENCY: Securities... principal capacity in transactions with certain of their advisory clients. The amendment would extend the... Advisers Act when they act in a principal capacity in transactions with certain of their advisory clients...

  15. Temporary occipital fixation in young children with severe cervical-thoracic spinal deformity.

    Science.gov (United States)

    Kelley, Brian J; Minkara, Anas A; Angevine, Peter D; Vitale, Michael G; Lenke, Lawrence G; Anderson, Richard C E

    2017-10-01

    OBJECTIVE The long-term effects of instrumentation and fusion of the occipital-cervical-thoracic spine on spinal growth in young children are poorly understood. To mitigate the effects of this surgery on the growing pediatric spine, the authors report a novel technique used in 4 children with severe cervical-thoracic instability. These patients underwent instrumentation from the occiput to the upper thoracic region for stabilization, but without bone graft at the craniovertebral junction (CVJ). Subsequent surgery was then performed to remove the occipital instrumentation, thereby allowing further growth and increased motion across the CVJ. METHODS Three very young children (15, 30, and 30 months old) underwent occipital to thoracic posterior segmental instrumentation due to cervical or upper thoracic dislocation, progressive kyphosis, and myelopathy. The fourth child (10 years old) underwent similar instrumentation for progressive cervical-thoracic scoliosis. Bone graft was placed at and distal to C-2 only. After follow-up CT scans demonstrated posterior arthrodesis without unintended fusion from the occiput to C-2, 3 patients underwent removal of the occipital instrumentation. RESULTS Follow-up cervical spine flexion/extension radiographs demonstrated partial restoration of motion at the CVJ. One patient has not had the occipital instrumentation removed yet, because only 4 months have elapsed since her operation. CONCLUSIONS Temporary fixation to the occiput provides increased biomechanical stability for spinal stabilization in young children, without permanently eliminating motion and growth at the CVJ. This technique can be considered in children who require longer instrumentation constructs for temporary stabilization, but who only need fusion in more limited areas where spinal instability exists.

  16. Stability of extemporaneously prepared glycopyrrolate oral suspensions.

    Science.gov (United States)

    Cober, Mary Petrea; Johnson, Cary E; Sudekum, David; Penprase, Kimberly

    2011-05-01

    The stability of extemporaneously prepared glycopyrrolate 0.5-mg/mL suspensions was evaluated. An oral suspension of glycopyrrolate 0.5 mg/mL was prepared by thoroughly grinding 30 1-mg tablets of glycopyrrolate in a glass mortar. Thirty milliliters of Ora-Plus and 30 mL of either Ora-Sweet or Ora-Sweet SF were mixed and added to the powder to make a final volume of 60 mL. Three identical samples of the formulation were prepared and placed in 2-oz amber plastic bottles with child-resistant caps and stored at room temperature (23-25 °C). A 1-mL sample was withdrawn from each of the three bottles with a micropipette immediately after preparation and 7, 15, 30, 60, and 90 days afterward. After further dilution to an expected concentration of 50 μg/mL with sample diluent, the samples were assayed in duplicate by stability-indicating high-performance liquid chromatography. The samples were visually examined for any color change and evaluated for pH on each day of analysis. Taste evaluations were performed at the beginning and end of the study. Stability was defined as the retention of at least 90% of the initial concentration. At least 95% of the initial glycopyrrolate remained throughout the 90-day study period in both preparations. There were no detectable changes in color, odor, taste, and pH, and no visible microbial growth was observed in any sample. Extemporaneously compounded suspensions of glycopyrrolate 0.5 mg/mL in a 1:1 mixture of Ora-Plus/Ora-Sweet or Ora-Plus/Ora-Sweet SF were stable for at least 90 days when stored in amber plastic bottles at room temperature.

  17. Omsättning, rörelseresultat och kapitalstruktur – Påverkas företags kapitalstruktur av förändringar i dess omsättning eller rörelseresultat?

    OpenAIRE

    Lisstorp, Mattias; Steinberger, Paul

    2012-01-01

    Syftet med uppsatsen är att undersöka hur omsättning och rörelseresultat har samband med företagets kapitalstruktur. Resultaten jämförs med befintlig teori för att verifiera de teoretiska ansatserna. Regressionsanalys av tidsserier för 32 svenska börsnoterade företag med mer än 20 miljarder svenska kronor i omsättning 2010 har använts vid den här undersökningen. Data från åren 2004 till 2010 till varje företag är tagen från databasen ”Affärsdata” och undersöks genom regressionsanalys. Först u...

  18. Models of collapsing and expanding anisotropic gravitating source in f(R, T) theory of gravity

    Energy Technology Data Exchange (ETDEWEB)

    Abbas, G. [The Islamia University of Bahawalpur, Department of Mathematics, Bahawalpur (Pakistan); Ahmed, Riaz [The Islamia University of Bahawalpur, Department of Mathematics, Bahawalpur (Pakistan); University of the Central Punjab, Department of Mathematics, Lahore (Pakistan)

    2017-07-15

    In this paper, we have formulated the exact solutions of the non-static anisotropic gravitating source in f(R, T) gravity which may lead to expansion and collapse. By assuming there to be no thermal conduction in gravitating source, we have determined parametric solutions in f(R, T) gravity with a non-static spherical geometry filled using an anisotropic fluid. We have examined the ranges of the parameters for which the expansion scalar becomes negative and positive, leading to collapse and expansion, respectively. Further, using the definition of the mass function, the conditions for the trapped surface have been explored, and it has been investigated that there exists a single horizon in this case. The impact of the coupling parameter λ has been discussed in detail in both cases. For the various values of the coupling parameter λ, we have plotted the energy density, anisotropic pressure and anisotropy parameter in the cases of collapse and expansion. The physical significance of the graphs has been explained in detail. (orig.)

  19. Evaluation of color stability of different temporary restorative materials

    Directory of Open Access Journals (Sweden)

    José Vitor Quinelli Mazaro

    Full Text Available AbstractIntroductionTemporary restorative materials are widely used, however, little is know about their color stability.Objectiveto evaluate the color stability of the following temporary restorative materials: acrylic and bis-acrylic resins after immersion in pigmenting solutions for different periods of storage.Material and methodFour materials were tested (Dêncor/Clássico, Protemp 4/3M ESPE; Structur 2 SC/Voco; Luxatemp AM Plus/DMG and 30 test specimens (15 mm in diameter and 2 mm thick per material were fabricated. They were divided according to the storage medium (artificial saliva, saliva + cola type soda, and saliva + coffee and storage time intervals (2, 5, 7 and 15 days. Color measurements were made before and after immersions, with use of a spectrophotometer, by means of the CIE L*a*b* system. The data were analyzed by the analysis of variance and the Tukey Test, at a level of significance of 5%.ResultAcrylic resin presented greater color stability in comparison with bis-acrylic resins (p<0.001. When bis-acrylic resins were compared no significant difference was observed between the resins Structur and Luxatemp (p=0.767. As regards solutions tested, coffee showed the highest color change values (p<0.001, and the longer the storage time interval, the greater was the color change in all the temporary restorative materials analyzed (p<0.001.ConclusionAcrylic resin presented greater color stability in comparison with bis-acrylic resins (p<0.001. Coffee caused the greatest color change, and immersion time was determinant in color stability of the temporary materials analyzed.

  20. 75 FR 38074 - Antidumping or Countervailing Duty Order, Finding, or Suspended Investigation; Opportunity To...

    Science.gov (United States)

    2010-07-01

    ...: Carboxymethylcellulose, A-421-811....... 7/1/09-6/30/10 Russia: Solid Urea, A-821-801 7/1/09-6/30/10 Ferrovanadium and.../09 Suspension Agreements Russia: Certain Hot-Rolled Carbon Steel Flat 7/1/09-6/30/10 Products, A-821... producer or exporter at the same time it files its request for review, in order for the Secretary to...

  1. Update on quadruple suspension design for Advanced LIGO

    International Nuclear Information System (INIS)

    Aston, S M; Carbone, L; Cutler, R M; Hoyland, D; Barton, M A; Bland, B; Bell, A S; Beveridge, N; Cagnoli, G; Cantley, C A; Cumming, A V; Cunningham, L; Hammond, G D; Haughian, K; Hough, J; Brummitt, A J; Greenhalgh, R J S; Hayler, T M; Heptonstall, A; Heefner, J

    2012-01-01

    We describe the design of the suspension systems for the major optics for Advanced LIGO, the upgrade to LIGO—the Laser Interferometric Gravitational-Wave Observatory. The design is based on that used in GEO600—the German/UK interferometric gravitational wave detector, with further development to meet the more stringent noise requirements for Advanced LIGO. The test mass suspensions consist of a four-stage or quadruple pendulum for enhanced seismic isolation. To minimize suspension thermal noise, the final stage consists of a silica mirror, 40 kg in mass, suspended from another silica mass by four silica fibres welded to silica ears attached to the sides of the masses using hydroxide-catalysis bonding. The design is chosen to achieve a displacement noise level for each of the seismic and thermal noise contributions of 10 −19 m/√Hz at 10 Hz, for each test mass. We discuss features of the design which has been developed as a result of experience with prototypes and associated investigations. (paper)

  2. Correlation between structure and rheological properties of suspension of nanosized powders

    Energy Technology Data Exchange (ETDEWEB)

    Tabellion, J.; Clasen, R. [Saarland Univ., Saarbruecken (Germany). Dept. of Powder Technology; Reinshagen, J.; Oberacker, R.; Hoffmann, M.J. [Karlsruhe Univ. (Germany). Inst. for Ceramics in Mechanical Engineering

    2002-07-01

    Since the properties of a ceramic green body and compact produced thereof are strongly influenced by the properties of the suspension used, controlling structure and properties of a suspension is a very important issue in ceramic manufacturing. Macroscopically, the rheological properties of a suspension are the key parameters that influence the behaviour during the shaping process. The rheological behaviour of aqueous suspensions of nanosized fumed silica (DEGUSSA, Aerosil OX50) with different amounts of OX50 (10 to 50 wt.%) was measured over a pH-range from 1 to 13 by means of rotational viscosimetry. A distinct maximum of the viscosity was observed for a pH of about 7 to 8, independent of the solid content of the suspensions. Since the rheological behaviour of the suspensions could not be explained by the {zeta}-Potential measured for OX50, the suspensions were investigated by means of so-called cryo-SEM characterization. A droplet of the suspension is quench-frozen in subcooled nitrogen (-210 C), prepared and the water is sublimed at -90 C. Thus it was possible to visualize the agglomerate structure of the primary OX50-particles within the suspensions. (orig.)

  3. Cationic polymers in water treatment: Part 2: Filterability of CPE-formed suspension

    Czech Academy of Sciences Publication Activity Database

    Polášek, P.; Mutl, Silvestr

    2002-01-01

    Roč. 28, č. 1 (2002), s. 83-88 ISSN 0378-4738 R&D Projects: GA AV ČR KSK2067107 Institutional research plan: CEZ:AV0Z2060917 Keywords : cationic polymers * water treatment * filterability of CPE-formed suspension Subject RIV: BK - Fluid Dynamics Impact factor: 0.481, year: 2002

  4. Thermodynamic geometry of black holes in f(R) gravity

    International Nuclear Information System (INIS)

    Soroushfar, Saheb; Saffari, Reza; Kamvar, Negin

    2016-01-01

    In this paper, we consider three types (static, static charged, and rotating charged) of black holes in f(R) gravity. We study the thermodynamical behavior, stability conditions, and phase transition of these black holes. It is shown that the number and type of phase transition points are related to different parameters, which shows the dependency of the stability conditions to these parameters. Also, we extend our study to different thermodynamic geometry methods (Ruppeiner, Weinhold, and GTD). Next, we investigate the compatibility of curvature scalar of geothermodynamic methods with phase transition points of the above black holes. In addition, we point out the effect of different values of the spacetime parameters on the stability conditions of mentioned black holes. (orig.)

  5. Cusp singularities in f(R) gravity: pros and cons

    International Nuclear Information System (INIS)

    Chen, Pisin; Yeom, Dong-han

    2015-01-01

    We investigate cusp singularities in f(R) gravity, especially for Starobinsky and Hu-Sawicki dark energy models. We illustrate that, by using double-null numerical simulations, a cusp singularity can be triggered by gravitational collapses. This singularity can be cured by adding a quadratic term, but this causes a Ricci scalar bump that can be observed by an observer outside the event horizon. Comparing with cosmological parameters, it seems that it would be difficult to see super-Planckian effects by astrophysical experiments. On the other hand, at once there exists a cusp singularity, it can be a mechanism to realize a horizon scale curvature singularity that can be interpreted by a firewall

  6. Re-design, re-use and recycle of temporary houses

    Energy Technology Data Exchange (ETDEWEB)

    Arslan, Hakan [Department of Construction, Faculty of Technical Education, University of Abant Izzet Baysal, Duzce 81100 (Turkey)

    2007-01-15

    Disasters are recurring to global problems, which results in homelessness. The affected region had economical, environmental and social problems as well. In relief and reconstruction phases, the need for integrated management appeared in order to use the national sources actively and productively. Especially housing implementations had an important role for future development of the affected region. For accelerating the reconstruction of the region and forming a sustainable community, which maintains itself socially, environmentally and economically over time; energy usage for construction should be kept to a minimum. Past research in Turkey shows that the cost of temporary houses (to be used as the short term shelter) had a ratio of 10-15% of the total expenses of whole construction activity. For saving money and protecting the environment and conserving scarce resources, the affected region must consider the option of temporary houses to meet their short and long-term need during the reconstruction process. After the end of usage, temporary houses should be able to be re-used for the same or new function. This study is a test of re-design and re-use of a temporary housing site; by using recycled materials, minimum energy and voluntary participation so that this site can finally become a permanent housing site. (author)

  7. The miR-10 microRNA precursor family

    DEFF Research Database (Denmark)

    Tehler, Disa; Høyland-Kroghsbo, Nina Molin; Lund, Anders H

    2011-01-01

    The miR-10 microRNA precursor family encodes a group of short non-coding RNAs involved in gene regulation. The miR-10 family is highly conserved and has sparked the interest of many research groups because of the genomic localization in the vicinity of, coexpression with and regulation of the Hox...... gene developmental regulators. Here, we review the current knowledge of the evolution, physiological function and involvement in cancer of this family of microRNAs....

  8. NMR relaxometric properties and cytotoxicity of Gd2O3 nanoparticle suspensions in an organic liquid

    Science.gov (United States)

    Babić-Stojić, Branka; Jokanović, Vukoman; Milivojević, Dušan; Požek, Miroslav; Jagličić, Zvonko; Makovec, Darko; Arsikin, Katarina; Paunović, Verica

    2014-10-01

    Gd2O3 nanoparticles and their agglomerates from approximately 10 to 80 nm in size suspended in an organic liquid were synthesized via polyol route. The reaction between diethylene glycol and added acetic acid, which occurred simultaneously with the synthesis of Gd2O3 nanoparticles, was catalyzed by sodium bisulfate to transform as much as possible diethylene glycol in corresponding ester at the end of complete reaction. The produced nanosized material of gadolinium oxide was investigated by TEM, DLS, FTIR spectroscopy, and NMR relaxometry. Biological evaluation of this material was done by MTT and crystal violet assays to determine the cell viability. Longitudinal and transverse relaxivities of water-diluted Gd2O3 nanoparticle suspensions estimated to be r 1 = 13.6 and r 2 = 14.7 s-1 mM-1 are about three times higher compared to the relaxivities obtained for standard contrast agent Gd-DTPA (Magnevist). Good MRI signal intensities of the water-diluted Gd2O3 nanoparticle suspensions were recorded in the Gd concentration range 0.2-0.3 mM for which the suspensions were not toxic exhibiting simultaneously higher signal intensities than those for Magnevist in the Gd concentration range 0.4-1 mM for which this standard contrast agent was not toxic. These properties make the produced Gd2O3 nanoparticle material promising for potential application as MRI contrast agent.

  9. Effects of escitalopram, R-citalopram, and reboxetine on serum levels of tumor necrosis factor-α, interleukin-10, and depression-like behavior in mice after lipopolysaccharide administration.

    Science.gov (United States)

    Dong, Chao; Zhang, Ji-chun; Yao, Wei; Ren, Qian; Yang, Chun; Ma, Min; Han, Mei; Saito, Ryo; Hashimoto, Kenji

    2016-05-01

    Inflammation plays a role in the pathophysiology of depression. The purpose of this study is to examine whether the selective serotonin reuptake inhibitor (SSRI) escitalopram, its inactive enantiomer R-citalopram, and selective noradrenaline reuptake inhibitor (NRI) reboxetine, show anti-inflammatory and antidepressant effects in an inflammation-induced model of depression. Pretreatment with escitalopram (1, 3, or 10mg/kg, i.p.) markedly blocked an increase in the serum levels of pro-inflammatory cytokine, tumor necrosis factor-α (TNF-α), after a single administration of lipopolysaccharide (LPS; 0.5mg/kg). Furthermore, escitalopram (3 or 10mg/kg) significantly increased the serum levels of the anti-inflammatory cytokine interleukin-10 (IL-10) by a single administration of LPS. In contrast, pretreatment with R-citalopram (10mg/kg, i.p.) or reboxetine (10mg/kg, i.p.) did not affect the alterations in serum levels of TNF-α and IL-10 after LPS administration. Co-administration of reboxetine with escitalopram did not show anti-inflammatory effects. Pretreatment with escitalopram (10mg/kg) significantly attenuated LPS-induced increase of the immobility time in the tail-suspension test (TST) and forced swimming test (FST). In contrast, pretreatment with R-citalopram (10mg/kg), or reboxetine (10mg/kg) did not alter LPS-induced increase of immobility time of TST and FST. Interestingly, co-administration of reboxetine with escitalopram did not show antidepressant effect in this model. These findings suggest that escitalopram, but not R-citalopram and reboxetine, has anti-inflammatory and antidepressant effects in LPS-treated model of depression, and that reboxetine can antagonize the effects of escitalopram in the inflammation model. Therefore, it is likely that serotonergic system plays a key role in the pathophysiology of inflammation-induced depression. Copyright © 2016 Elsevier Inc. All rights reserved.

  10. Long-term safety and outcome of a temporary self-expanding metallic stent for achalasia: a prospective study with a 13-year single-center experience

    Energy Technology Data Exchange (ETDEWEB)

    Zhao, Jun-Gong; Li, Yong-Dong; Li, Ming-Hua; Shang, Ke-Zhong [Shanghai Tong Ji University, Department of Radiology, Tenth Affiliated People' s Hospital, Shanghai (China); Cheng, Ying-Sheng [Shanghai Tong Ji University, Department of Radiology, Tenth Affiliated People' s Hospital, Shanghai (China); Shanghai Jiao Tong University, Department of Radiology, Sixth Affiliated People' s Hospital, Shanghai (China); Chen, Ni-Wei; Chen, Wei-Xiong [Shanghai Jiao Tong University, Department of Gastroenterology, Sixth Affiliated People' s Hospital, Shanghai (China)

    2009-08-15

    To prospectively evaluate the long-term clinical safety and efficacy of a newly designed self-expanding metallic stent (SEMS) in the treatment of patients with achalasia. Seventy-five patients with achalasia were treated with a temporary SEMS with a 30-mm diameter. The SEMSs were placed under fluoroscopic guidance and removed by gastroscopy 4-5 days after stent placement. Follow-up data focused on dysphagia score, technique and clinical success, clinical remissions and failures, and complications and was performed at 6 months, 1 year, and within 3 to 5 years, 5 to 8 years, 8 to 10 years, and >10 years postoperatively. Stent placement was technically successful in all patients. Complications included stent migration (n=4, 5.33%), chest pain (n=28, 38.7%), reflux (n=15, 20%), and bleeding (n=9, 12%). No perforation or 30-day mortality occurred. Clinical success was achieved in all patients 1 month after stent removal. The overall remission rates at 6 months, 1, 1-3, 3-5, 5-8, 8-10, and >10 year follow-up periods were 100%, 96%, 93.9%, 90.9%, 100%, 100%, and 83.3%, respectively. Stent treatment failed in six patients, and the overall remission rate in our series was 92%. The median and mean primary patencies were 2.8 {+-} 0.28 years (95% CI: 2.25-3.35) and 4.28 {+-} 0.40 years (95% CI: 3.51-5.05), respectively. The use of temporary SEMSs with 30-mm diameter proved to be a safe and effective approach for managing achalasia with a long-term satisfactory clinical remission rate. (orig.)

  11. 38 CFR 60.10 - Costs.

    Science.gov (United States)

    2010-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2010-07-01 2010-07-01 false Costs. 60.10 Section 60.10 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS (CONTINUED) FISHER HOUSES AND OTHER TEMPORARY LODGING § 60.10 Costs. Costs for temporary lodging under this part shall be borne...

  12. Influence of temporary cement contamination on the surface free energy and dentine bond strength of self-adhesive cements.

    Science.gov (United States)

    Takimoto, Masayuki; Ishii, Ryo; Iino, Masayoshi; Shimizu, Yusuke; Tsujimoto, Akimasa; Takamizawa, Toshiki; Ando, Susumu; Miyazaki, Masashi

    2012-02-01

    The surface free energy and dentine bond strength of self-adhesive cements were examined after the removal of temporary cements. The labial dentine surfaces of bovine mandibular incisors were wet ground with #600-grit SiC paper. Acrylic resin blocks were luted to the prepared dentine surfaces using HY Bond Temporary Cement Hard (HY), IP Temp Cement (IP), Fuji TEMP (FT) or Freegenol Temporary Cement (TC), and stored for 1 week. After removal of the temporary cements with an ultrasonic tip, the contact angle values of five specimens per test group were determined for the three test liquids, and the surface-energy parameters of the dentine surfaces were calculated. The dentine bond strengths of the self-adhesive cements were measured after removal of the temporary cements in a shear mode at a crosshead speed of 1.0mm/min. The data were subjected to one-way analysis of variance (ANOVA) followed by Tukey's HSD test. For all surfaces, the value of the estimated surface tension component γ(S)(d) (dispersion) was relatively constant at 41.7-43.3 mJm(-2). After removal of the temporary cements, the value of the γ(S)(h) (hydrogen-bonding) component decreased, particularly with FT and TC. The dentine bond strength of the self-adhesive cements was significantly higher for those without temporary cement contamination (8.2-10.6 MPa) than for those with temporary cement contamination (4.3-7.1 MPa). The γ(S) values decreased due to the decrease of γ(S)(h) values for the temporary cement-contaminated dentine. Contamination with temporary cements led to lower dentine bond strength. The presence of temporary cement interferes with the bonding performance of self-adhesive cements to dentine. Care should be taken in the methods of removal of temporary cement when using self-adhesive cements. Copyright © 2011 Elsevier Ltd. All rights reserved.

  13. 75 FR 81856 - Security Zone, Michoud Slip Position 30°0′34.2″ N, 89°55′40.7″ W to Position 30°0′29.5″ N, 89°55...

    Science.gov (United States)

    2010-12-29

    ...-AA87 Security Zone, Michoud Slip Position 30[deg]0'34.2'' N, 89[deg]55'40.7'' W to Position 30[deg]0'29.5'' N, 89[deg]55'52.6'' W AGENCY: Coast Guard, DHS. ACTION: Temporary final rule. SUMMARY: The... position 30[deg]0'34.2'' N, 89[deg]55'40.7'' W to position 30[deg]0'29.5'' N, 89[deg]55'52.6'' W across the...

  14. 78 FR 12127 - Vitaminspice Inc.; Order of Suspension of Trading

    Science.gov (United States)

    2013-02-21

    ... periodic financial filings and in internet promotions concerning, among other things, the company's... SECURITIES AND EXCHANGE COMMISSION [File No. 500-1] Vitaminspice Inc.; Order of Suspension of Trading February 19, 2013. It appears to the Securities and Exchange Commission that there is a lack of...

  15. Enabling high-rate electrochemical flow capacitors based on mesoporous carbon microspheres suspension electrodes

    Science.gov (United States)

    Tian, Meng; Sun, Yueqing; Zhang, Chuanfang (John); Wang, Jitong; Qiao, Wenming; Ling, Licheng; Long, Donghui

    2017-10-01

    Electrochemical flow capacitor (EFC) is a promising technology for grid energy storage, which combines the fast charging/discharging capability of supercapacitors with the scalable energy capacity of flow batteries. In this study, we report a high-power-density EFC using mesoporous carbon microspheres (MCMs) as suspension electrodes. By using a simple yet effective spray-drying technique, monodispersed MCMs with average particle size of 5 μm, high BET surface area of 1150-1267 m2 g-1, large pore volume of 2-4 cm3 g-1 and controllable mesopore size of 7-30 nm have been successfully prepared. The resultant MCMs suspension electrode shows excellent stability and considerable high capacitance of 100 F g-1 and good cycling ability (86% of initial capacitance after 10000 cycles). Specially, the suspension electrode exhibits excellent rate performance with 75% capacitance retention from 2 to 100 mV s-1, significantly higher than that of microporous carbon electrodes (20∼30%), due to the developed mesoporous channels facilitating for rapid ion diffusion. In addition, the electrochemical responses on both negative and positive suspension electrodes are studied, based on which an optimal capacitance matching between them is suggested for large-scale EFC unit.

  16. 45 CFR 1177.12 - Compromise, suspension and termination.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 3 2010-10-01 2010-10-01 false Compromise, suspension and termination. 1177.12 Section 1177.12 Public Welfare Regulations Relating to Public Welfare (Continued) NATIONAL FOUNDATION ON...) debts arising from GAO audit exceptions. ...

  17. 75 FR 742 - Temporary Rule Regarding Principal Trades With Certain Advisory Clients

    Science.gov (United States)

    2010-01-06

    ... SECURITIES AND EXCHANGE COMMISSION 17 CFR Part 275 [Release No. IA-2965A; File No. S7-23-07] RIN 3235-AJ96 Temporary Rule Regarding Principal Trades With Certain Advisory Clients AGENCY: Securities... transactions with certain of their advisory clients. As adopted, the only change to the rule was the expiration...

  18. 75 FR 16000 - Temporary Employment of Foreign Workers in the United States

    Science.gov (United States)

    2010-03-31

    ... out the policies of the Immigration and Nationality Act (INA), that a nonimmigrant alien worker not be admitted to fill a particular temporary job opportunity unless no qualifed U.S. worker is available to fill the job opportunity, and unless the employment of the foreign worker in the job opportunity will not...

  19. 78 FR 7849 - Culturally Significant Objects Imported for Exhibition

    Science.gov (United States)

    2013-02-04

    ... Century,'' imported from abroad for temporary exhibition within the United States, are of cultural... also determine that the exhibition or display of the exhibit objects at The Yale Center for British Art..., Bureau of Educational and Cultural Affairs, Department of State. [FR Doc. 2013-02401 Filed 2-1-13; 8:45...

  20. Spectral analysis connected with suspension bridge systems

    Czech Academy of Sciences Publication Activity Database

    Malík, Josef

    2016-01-01

    Roč. 81, č. 1 (2016), s. 42-75 ISSN 0272-4960 R&D Projects: GA MŠk ED2.1.00/03.0082 Institutional support: RVO:68145535 Keywords : suspension bridge * vertical and torsional oscillation * eigenvalue * eigenvector * flutter Subject RIV: JM - Building Engineering Impact factor: 0.945, year: 2016 http://imamat.oxfordjournals.org/content/early/2015/09/16/imamat.hxv027.short?rss=1

  1. The effect of compatibility of suspension particles with the oil medium on electrorheological efficiency

    Czech Academy of Sciences Publication Activity Database

    Stěnička, M.; Pavlínek, V.; Sáha, P.; Blinova, Natalia V.; Stejskal, Jaroslav; Quadrat, Otakar

    2012-01-01

    Roč. 23, č. 9 (2012), s. 1055-1059 ISSN 1045-389X R&D Projects: GA ČR GA202/09/1626; GA AV ČR IAA400500905 Institutional research plan: CEZ:AV0Z40500505 Keywords : electrorheological * suspension * polyaniline Subject RIV: CD - Macromolecular Chemistry Impact factor: 1.523, year: 2012

  2. Predicting the viscosity of digesta from the physical characteristics of particle suspensions using existing rheological models.

    Science.gov (United States)

    Hardacre, Allan K; Lentle, Roger G; Yap, Sia-Yen; Monro, John A

    2018-05-01

    The measurement of the viscosity of digesta is complicated by settling and compositional changes that accompany digestion. The current work determined whether the apparent and relative viscosities ( η a and η r ) of digesta could be accurately determined from the actual and maximum solid volume fractions ( ϕ and ϕ max , respectively) using the Maron-Pierce equation. The rheological properties of digesta from the small intestine of six pigs were determined at a shear rate of 1 s -1 at 37°C. A series of suspensions of plant fibre in a Newtonian liquid (70% aqueous fructose) were made at viscosities similar to pig digesta by adjusting ϕ The relationships between the apparent and relative viscosities ( η a and η r ) and the plant fibre properties; aspect ratio (AR) and ϕ and ϕ max were then determined for digesta and the suspensions. The ARs for the digesta and plant fibre particles were determined using image analysis of scanning electron micrographs and η a from rheometric flow curves at 37°C, ϕ from image analysis and gas pycnometry, and ϕ max from AR and suspension viscosity. The η r of pig digesta and the test suspensions calculated using the Maron-Pierce equation were, with the exception of two outliers, in proportion with η a determined using a rheometer, indicating that η r could be successfully predicted from the Maron-Pierce equation. © 2018 The Author(s).

  3. 76 FR 30827 - Temporary Change of Dates for Recurring Marine Event in the Fifth Coast Guard District; Elizabeth...

    Science.gov (United States)

    2011-05-27

    ...-AA08 Temporary Change of Dates for Recurring Marine Event in the Fifth Coast Guard District; Elizabeth River, Norfolk, VA AGENCY: Coast Guard, DHS. ACTION: Temporary final rule. SUMMARY: The Coast Guard will... various river boat races and a parade during the ``35th Annual Norfolk Harborfest Celebration.'' Special...

  4. Temporary workers in the nuclear power industry: implications for the waste management program

    International Nuclear Information System (INIS)

    Melville, M.H.

    1984-01-01

    The employment of large number of temporary workers has become a growing and permanent characteristic of the nuclear power industry. In order to stay within the limits governing individual exposure to radiation in the workplace, the occupational risk has been spread among a larger segment of the population. Temporary workers, who make up one-third of the industry's work force, bear a disproportionate share of half the total annual occupational radiation dose. At issue is whether temporary workers should be grouped with the public at large or with the nuclear industry's work force, whose maximum limits are at least 10 times higher. This issue is relevant at a time when the search for a way to manage the mounting radioactive wastes will increase both the permanent and temporary work force. 44 references, 4 figures, 4 tables

  5. Experimental study of domestic inferior vena cava filter comparative to Antheor temporary vena cava filter in vitro

    International Nuclear Information System (INIS)

    Chen Guoping; Gu Jianping; Lou Wensheng; He Xu; Chen Liang; Su Haobo

    2007-01-01

    Objective: To evaluate clot capturing efficacy and stability of a new domestic designed inferior vena cava filter (DDIVCF) by comparing with Anthem temporary vena cava filter in vitro. Methods: (1)The DDIVCF and Antheor filter were tested in a flow model simulated the inferior vena cava (IVC) with 20 mm and 25 mm in diameter. The swine clots of four sizes were used: 3 mm x 20 mm, 3 mm x 30 mm, 6 mm x 20 mm, 6 mm x 30 mm. The clot capturing capacity was observed in horizontal position. (2) The stability was observed by measuring the comparative moving distance of 6 mm x 30 mm clots after clot trapping. Results: (1) DDIVCF capture rates were 34%, 56%, 82%, 94% and 26%, 38%, 56%, 86% for the 20 mm and 25 mm IVC models of four different sizes clots respectively, comparing with 54%, 64%, 86%, 96% and 38%, 44%, 68%, 90% respectively of Anthem temporary vena cava filter. The capture rates of DDIVCF and Antheor filter showed no significant differences of 3 mm x 30 mm, 6mm x 20 mm and 6 mm x 30 mm clots in 20 mm and 25 mm IVC models (P>0.05). (2) There was a few caudal migration with no significant difference (P>0.05). The filter migration distances were (0.6±0.3) cm and (1.0±0.1) cm respectively in the 20 mm and 25 mm IVC models with most clots of 6 mm x 30 mm were captured, comparing with (0.4±0.1) cm and (0.8 ±0.3) cm respectively for Antheor filter. Conclusions: DDIVCF is a stable and effective filter in an in-vitro model experiment but application in vivo would rather be further evaluated through more animal experiments. (authors)

  6. Hydropneumatic suspension systems

    Energy Technology Data Exchange (ETDEWEB)

    Bauer, Wolfgang

    2011-07-01

    Hydropneumatic suspensions systems combine the excellent properties of gas springs with the favourable damping properties of hydraulic fluids. The advantages of these systems are particularly appropriate for automotive applications, such as passenger cars, trucks and agricultural equipment. In this book, Dr. Bauer provides an extensive overview of hydropneumatic suspension systems. Starting with a comparison of different types of suspension systems, the author subsequently describes the theoretical background associated with spring and damping characteristics of hydropneumatic systems and furthermore explains the design of the most important system components. Additionally he gives an overview of level control systems and various special functions. Finally the technology is illustrated by design examples and the outlook for future hydropneumatic suspensions is discussed. (orig.)

  7. (2S,4aR,6aR,7R,9S,10aS,10bR-7-Carboxy-2-(3-furyl-6a,10b-dimethyl-4,10-dioxoperhydrobenzo[f]isochromen-9-yl acetate

    Directory of Open Access Journals (Sweden)

    2009-03-01

    Full Text Available The asymmetric unit of the title compound, C22H26O8, contains two crystallographically independent molecules with closely comparable conformations (r.m.s. overlay = 0.54 Å for 30 non-H atoms. All six-membered rings display chair conformations, with a slight distortion for the lactone ring. The molecules are connected by O—H...O hydrogen bonds into chains along [010], with the independent molecules segregated into separate chains. The two molecules in the asymmetric unit face each other in a head-to-tail fashion, with the furan ring of one molecule turned towards the carboxylic acid terminal of the other molecule.

  8. 76 FR 52563 - Special Local Regulations; Sabine River, Orange, TX

    Science.gov (United States)

    2011-08-23

    ...-AA08 Special Local Regulations; Sabine River, Orange, TX AGENCY: Coast Guard, DHS. ACTION: Temporary... Regulations; Sabine River, Orange, TX in the Federal Register (76 FR 103). We received no comments on the... Regulations for Marine Events; Sabine River, Orange, TX. (a) Definitions. As used in this section...

  9. 30 CFR 906.10 - State regulatory program approval.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 3 2010-07-01 2010-07-01 false State regulatory program approval. 906.10 Section 906.10 Mineral Resources OFFICE OF SURFACE MINING RECLAMATION AND ENFORCEMENT, DEPARTMENT OF THE INTERIOR PROGRAMS FOR THE CONDUCT OF SURFACE MINING OPERATIONS WITHIN EACH STATE COLORADO § 906.10 State...

  10. Effects of 60Co γ-rays irradiation on cell growth and alkaloid accumulation of protocorm-like bodies in suspension cultures from Dendrobium huoshanense

    International Nuclear Information System (INIS)

    Hong Sali; Jin Qing; Huang Bei; Cai Yongping; Lin Yi

    2009-01-01

    Protocorm-like bodies (PLBs) in suspension cultures from Dendrobium huoshanense were irradiated by 60 Co γ-rays at doses of 5, 10, 20 and 30Gy, and alkaloid accumulation of PLBs was studied. The results showed that 60 Co γ-rays irradiation could improve the alkaloid content of PLBs, and the suitable dose was 10Gy. The fresh weight of 10Gy irradiated PLBs was 26.54g/flask, and the alkaloid content was 0.035% on the 36th day. The medium pH and electric conductivity of 10Gy irradiated PLBs changed slightly during the suspension culture period. The results suggested such cultural environment was suitable for PLBs growth continuely. Results also showed that 60 Co γ-rays irradiation could increase the activities of POD, SOD, CAT, PAL and decrease the activity of PPO, these were responsible for the improvement of cell growth and alkaloid accumulation in PLBs. (authors)

  11. Rheological Properties of Aqueous Nanometric Alumina Suspensions

    Energy Technology Data Exchange (ETDEWEB)

    Li, Chuanping [Iowa State Univ., Ames, IA (United States)

    2004-01-01

    ' surfaces in the aqueous suspension. The viscosity of the suspension increases dramatically when the solid volume fraction exceeds 30 vol.%. The overlap of physically adsorbed water layers at this level causes the sharp increase in viscosity. Fructose molecules can weaken the interactions between the particle surfaces and water molecules, as a consequence, they release some bound water layers from the surfaces to the bulk medium. It is believed that fraction of the water that is bound by the solid surface is reduced hence becoming available for flow. The oxygen-17 relaxation time decreased with the increase of particle volume fractions in the suspension. Fructose addition increased the overall water mobility in the suspension. Only part of the alumina particle surfaces was covered with fructose molecules. This adsorption of fructose molecules on the particle surfaces increased the pH of the suspension with a concomitant decrease in ζ-potential of the alumina nanoparticles. The interactions between the nanometric alumina particles in water to a large extent can be explained by the DLVO theory. However, the interactions between particles in fructose solutions cannot be well described by the DLVO theory. The interaction forces (magnitude and range) as well as adhesive force and surface tension between nanometric alumina particles were decreased with the fructose concentration.

  12. Radial force distribution changes associated with tangential force production in cylindrical grasping, and the importance of anatomical registration.

    Science.gov (United States)

    Pataky, Todd C; Slota, Gregory P; Latash, Mark L; Zatsiorsky, Vladimir M

    2012-01-10

    Radial force (F(r)) distributions describe grip force coordination about a cylindrical object. Recent studies have employed only explicit F(r) tasks, and have not normalized for anatomical variance when considering F(r) distributions. The goals of the present study were (i) to explore F(r) during tangential force production tasks, and (ii) to examine the extent to which anatomical registration (i.e. spatial normalization of anatomically analogous structures) could improve signal detectability in F(r) data. Twelve subjects grasped a vertically oriented cylindrical handle (diameter=6 cm) and matched target upward tangential forces of 10, 20, and 30 N. F(r) data were measured using a flexible pressure mat with an angular resolution of 4.8°, and were registered using piecewise-linear interpolation between five manually identified points-of-interest. Results indicate that F(r) was primarily limited to three contact regions: the distal thumb, the distal fingers, and the fingers' metatacarpal heads, and that, while increases in tangential force caused significant increases in F(r) for these regions, they did not significantly affect the F(r) distribution across the hand. Registration was found to substantially reduce between-subject variability, as indicated by both accentuated F(r) trends, and amplification of the test statistic. These results imply that, while subjects focus F(r) primarily on three anatomical regions during cylindrical grasp, inter-subject anatomical differences introduce a variability that, if not corrected for via registration, may compromise one's ability to draw anatomically relevant conclusions from grasping force data. Copyright © 2011 Elsevier Ltd. All rights reserved.

  13. 75 FR 68970 - Amendment of Using Agency for Restricted Areas R-4002, R-4005, R-4006 and R-4007; MD

    Science.gov (United States)

    2010-11-10

    ...-1070; Airspace Docket No. 10-AEA-18] RIN 2120-AA66 Amendment of Using Agency for Restricted Areas R-4002, R-4005, R- 4006 and R-4007; MD AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action makes a minor change to the name of the using agency for restricted areas R...

  14. Betydelsen av historisk rättvisa efter kolonialismen

    Directory of Open Access Journals (Sweden)

    Göran Collste

    2012-05-01

    Full Text Available Artikeln tar sin utgångspunkt i två aktuella exempel på krav på historisk rättvisa efter kolonialismen: forna Mau-Mau-kämpars krav på gottgörelse för britternas övergrepp på 1950-talet och hererofolkets krav till Tyskland på gottgörelse för det folkmord som ägde rum 1904–1907. Dessa exempel aktualiserar frågan om historisk rättvisa. Vad innebär historisk rättvisa? Vilka krav på historisk rättvisa är berättigade att ställa? Hur lång tid efter övergrepp och våld finns det skäl att kräva gottgörelse? Kan kraven ärvas till efterkommande generationer? Vem bör gottgöra dem som drabbats? Dessa frågor måste besvaras för att man skall kunna ta ställning till krav på gottgörelse och rättvisa. Syftet med denna artikel är att identifiera och söka besvara en rad frågor som krav på gottgörande rättvisa efter kolonialismen ställer. Avslutningsvis diskuteras kraven från Mau-Mau-kämparna som var internerade i brittiska läger och hererofolkets krav på kompensation från Tyskland.Nyckelord: Gottgörande rättvisa, kompensation, kolonialism, herero, Mau-Mau, global rättvisa, historisk rättvisaEnglish summary: The Meaning of Historical Justice after ColonialismRecently, four Kikuyus and former Kenyan Mau-Mau fighters claimed compensation for castration, torture and rape committed in the British detention camps in the 1950s. Also recently, representatives of the Herero people went to Berlin to bring home skulls that Germans brought to Berlin after the genocide at the beginning of the Twentieth Century. The detentions and abuses of Kikuyu and the genocide of the Herero people are just two examples of offenses carried out by European nations during colonialism. Do these offenses have any reverberations today? Should we simply forget about the deeds that happened such a long time ago or do they raise any legal or moral questions?The concept of justice has two dimensions, distributional and rectificatory. This

  15. Particle interactions in concentrated suspensions

    International Nuclear Information System (INIS)

    Mondy, L.A.; Graham, A.L.; Abbott, J.R.; Brenner, H.

    1993-01-01

    An overview is presented of research that focuses on slow flows of suspensions in which colloidal and inertial effects are negligibly small. The authors describe nuclear magnetic resonance imaging experiments to quantitatively measure particle migration occurring in concentrated suspensions undergoing a flow with a nonuniform shear rate. These experiments address the issue of how the flow field affects the microstructure of suspensions. In order to understand the local viscosity in a suspension with such a flow-induced, spatially varying concentration, one must know how the viscosity of a homogeneous suspension depends on such variables as solids concentration and particle orientation. The authors suggest the technique of falling ball viscometry, using small balls, as a method to determine the effective viscosity of a suspension without affecting the original microstructure significantly. They also describe data from experiments in which the detailed fluctuations of a falling ball's velocity indicate the noncontinuum nature of the suspension and may lead to more insights into the effects of suspension microstructure on macroscopic properties. Finally, they briefly describe other experiments that can be performed in quiescent suspensions (in contrast to the use of conventional shear rotational viscometers) in order to learn more about boundary effects in concentrated suspensions

  16. Temporary physical protection systems

    International Nuclear Information System (INIS)

    Williams, J.D.; Gangel, D.J.; Madsen, R.W.

    1991-01-01

    Terrorism and other aspects of world political instability have created a high demand for temporary physical protection systems within the nuclear materials management community. They can be used when vehicles carrying important assets are away from their permanent fixed site location, around areas where experiments are being temporarily conducted, around construction areas and one portions of a fixed site physical security system which is temporarily inoperable. Physical security systems can be grouped into four categories: tactical, portable, semi-permanent, and fixed. The resources and experience gained at Sandia National Laboratories in over forty years of developing and implementing security systems for protecting nuclear weapons and fixed nuclear facilities is now being applied to temporary physical security systems. This paper emphasizes temporary physical security systems and their component parts that are presently available and identify additional system-subsystem objectives, requirements, and concepts

  17. 75 FR 6160 - Airworthiness Directives; McDonnell Douglas Corporation Model DC-10-10, DC-10-10F, DC-10-15, DC...

    Science.gov (United States)

    2010-02-08

    ...-0032; Directorate Identifier 2009-NM-213-AD] RIN 2120-AA64 Airworthiness Directives; McDonnell Douglas...: McDonnell Douglas Corporation: Docket No. FAA-2010-0032; Directorate Identifier 2009-NM-213-AD. Comments Due... applies to McDonnell Douglas Corporation Model DC- 10-10, DC-10-10F, DC-10-15, DC-10-30, DC-10-30F (KC-10A...

  18. 76 FR 68808 - Culturally Significant Objects Imported for Exhibition

    Science.gov (United States)

    2011-11-07

    ... also determine that the exhibition or display of the exhibit objects at the Onassis Cultural Center... Century AD,'' imported from abroad for temporary exhibition within the United States, are of cultural... Cultural Affairs, Department of State. [FR Doc. 2011-28805 Filed 11-4-11; 8:45 am] BILLING CODE 4710-05-P ...

  19. Self-powered suspension criterion and energy regeneration implementation scheme of motor-driven active suspension

    Science.gov (United States)

    Yan, Shuai; Sun, Weichao

    2017-09-01

    Active suspension systems have advantages on mitigating the effects of vehicle vibration caused by road roughness, which are one of the most important component parts in influencing the performances of vehicles. However, high amount of energy consumption restricts the application of active suspension systems. From the point of energy saving, this paper presents a self-powered criterion of the active suspension system to judge whether a motor-driven suspension can be self-powered or not, and then a motor parameter condition is developed as a reference to design a self-powered suspension. An energy regeneration implementation scheme is subsequently proposed to make the active suspension which has the potential to be self-powered achieve energy-saving target in the real application. In this implementation scheme, operating electric circuits are designed based on different working status of the actuator and power source and it is realizable to accumulate energy from road vibration and supply energy to the actuator by switching corresponding electric circuits. To apply the self-powered suspension criterion and energy regeneration implementation scheme, an active suspension system is designed with a constrained H∞ controller and calculation results indicate that it has the capability to be self-powered. Simulation results show that the performances of the self-powered active suspension are nearly the same as those of the active suspension with an external energy source and can achieve energy regeneration at the same time.

  20. Implications of extreme flatness in a general f(R theory

    Directory of Open Access Journals (Sweden)

    Michał Artymowski

    2016-09-01

    Full Text Available We discuss a modified gravity theory defined by f(R=∑nlαnM2(1−nRn. We consider both finite and infinite number of terms in the series while requiring that the Einstein frame potential of the theory has a flat area around any of its stationary points. We show that the requirement of maximally flat stationary point leads to the existence of the saddle point (local maximum for even (odd l. In both cases for l→∞ one obtains the Starobinsky model with small, exponentially suppressed corrections. Besides the GR minimum the Einstein frame potential has an anti de Sitter vacuum. However we argue that the GR vacuum is absolutely stable and AdS can be reached neither via classical evolution nor via quantum tunnelling. Our results show that a Starobinsky-like model is the only possible realisation of f(R theory with an extremely flat area in the Einstein frame potential.

  1. Process and device for the extraction of ions from a clear liquid or one containing matter in suspension with a ion exchanger

    International Nuclear Information System (INIS)

    Capitani, Enzo; Teissie, Jean.

    1982-01-01

    Process for the continuous extraction of ions from a clear liquid or one containing matter in suspension by the use of a bed of ion exchange grains which is fluidized inside a column by circulation of the liquid, characterized by the fact that the said bed is subject to cyclic pulsations, in order to obtain sorting of the grains by density, the heavier grains having fixed the maximum ions. This invention can be applied for the continuous extraction of any type of anion or cation or exchangeable salt by means of resins or inorganic exchangers, to avoid clogging and abrasion problems, and to obtain maximum extraction rate and capacity. An example is given of the treatment of a suspension for the extraction of uranium [fr

  2. Measuring persistence to hormonal therapy in patients with breast cancer: accounting for temporary treatment discontinuation.

    Science.gov (United States)

    Huiart, Laetitia; Ferdynus, Cyril; Dell'Aniello, Sophie; Bakiri, Naciba; Giorgi, Roch; Suissa, Samy

    2014-08-01

    Several studies have been conducted to estimate persistence to hormonal therapy among women with breast cancer (BC). Most studies focus on first treatment discontinuation. Patients, however, can have numerous periods of treatment discontinuation or treatment exposure. Our objective is to estimate persistence to tamoxifen in patients with BC while accounting for temporary treatment discontinuations and this by using multi-state (MS) models. A cohort of 10,806 women with BC having received at least one prescription of tamoxifen between 1998 and 2008 was constituted from the UK General Practice Research Database. We fitted a semi-Markov model with three states to estimate the probability of being off treatment over a 5-year period while accounting for temporary treatment discontinuations (transition between on treatment and off treatment) and competing risks (recurrence of BC or death). Non-persistence, as estimated from the MS model, ranged from 12.1% (95% confidence interval [95%CI]: 9.2-15.1) at 1 year to 14.9% (95%CI: 11.7-18.1) at 5 years. Estimations of non-persistence based on the Kaplan-Meier model were higher, i.e., 29.3% (95%CI: 28.1-30.6) at 5 years, as well as those obtained from a competing risk model, i.e., 24.0% (95%CI: 22.9-25.1). Most temporary discontinuations (94.7%) lasted less than 6 months. Temporary treatment discontinuations are frequent and should be accounted for when measuring adherence to treatment. MS models can provide a useful framework for this sort of analysis insofar as they help describe patients' complex behavior. This may help tailor interventions that improve persistence to hormonal therapy among women with BC. Copyright © 2014 John Wiley & Sons, Ltd.

  3. MiR-30b Attenuates Neuropathic Pain by Regulating Voltage-Gated Sodium Channel Nav1.3 in Rats

    Directory of Open Access Journals (Sweden)

    Songxue Su

    2017-05-01

    Full Text Available Nav1.3 is a tetrodotoxin-sensitive isoform among voltage-gated sodium channels that are closely associated with neuropathic pain. It can be up-regulated following nerve injury, but its biological function remains uncertain. MicroRNAs (miRNAs are endogenous non-coding RNAs that can regulate post-transcriptional gene expression by binding with their target mRNAs. Using Target Scan software, we discovered that SCN3A is the major target of miR-30b, and we then determined whether miR-30b regulated the expression of Nav1.3 by transfecting miR-30b agomir through the stimulation of TNF-α or by transfecting miR-30b antagomir in primary dorsal root ganglion (DRG neurons. The spinal nerve ligation (SNL model was used to determine the contribution of miR-30b to neuropathic pain, to evaluate changes in Nav1.3 mRNA and protein expression, and to understand the sensitivity of rats to mechanical and thermal stimuli. Our results showed that miR-30b agomir transfection down-regulated Nav1.3 mRNA stimulated with TNF-α in primary DRG neurons. Moreover, miR-30b overexpression significantly attenuated neuropathic pain induced by SNL, with decreases in the expression of Nav1.3 mRNA and protein both in DRG neurons and spinal cord. Activation of Nav1.3 caused by miR-30b antagomir was identified. These data suggest that miR-30b is involved in the development of neuropathic pain, probably by regulating the expression of Nav1.3, and might be a novel therapeutic target for neuropathic pain.Perspective: This study is the first to explore the important role of miR-30b and Nav1.3 in spinal nerve ligation-induced neuropathic pain, and our evidence may provide new insight for improving therapeutic approaches to pain.

  4. Inventory of nuclear power plants and research reactors temporary or definitively stopped in industrialized countries

    International Nuclear Information System (INIS)

    Clauzon, J.; Vaubert, B.

    1984-12-01

    This paper presents data and information on the end of the life of nuclear reactors. One deals more particularly with installations of industrialized countries. This report gives the motivations which have involved the definitive shut down of nuclear power plants and of research reactors in the concerned countries. A schedule of definitive reactor shutdowns is presented. Then, one deals with nuclear power plants of which the construction has been stopped. The reasons of these situations are also given. The temporary difficulties met during the construction or the starting of nuclear power plants these last years are mentioned. Most times, there are economical or political considerations, or safety reasons. Finally, the nuclear power plants stopped for more than two years are mentioned [fr

  5. Development of an optimized tetracycline-inducible expression system to increase the accumulation of interleukin-10 in tobacco BY-2 suspension cells.

    Science.gov (United States)

    Bortesi, Luisa; Rademacher, Thomas; Schiermeyer, Andreas; Schuster, Flora; Pezzotti, Mario; Schillberg, Stefan

    2012-07-11

    Plant cell suspension cultures can be used for the production of valuable pharmaceutical and industrial proteins. When the recombinant protein is secreted into the culture medium, restricting expression to a defined growth phase can improve both the quality and quantity of the recovered product by minimizing proteolytic activity. Temporal restriction is also useful for recombinant proteins whose constitutive expression affects cell growth and viability, such as viral interleukin-10 (vIL-10). We have developed a novel, tetracycline-inducible system suitable for tobacco BY-2 suspension cells which increases the yields of vIL-10. The new system is based on a binary vector that is easier to handle than conventional vectors, contains an enhanced inducible promoter and 5'-UTR to improve yields, and incorporates a constitutively-expressed visible marker gene to allow the rapid and straightforward selection of the most promising transformed clones. Stable transformation of BY-2 cells with this vector, without extensive optimization of the induction conditions, led to a 3.5 fold increase in vIL-10 levels compared to constitutive expression in the same host. We have developed an effective and straightforward molecular farming platform technology that improves both the quality and the quantity of recombinant proteins produced in plant cells, particularly those whose constitutive expression has a negative impact on plant growth and development. Although we tested the platform using vIL-10 produced in BY-2 cells, it can be applied to other host/product combinations and is also useful for basic research requiring strictly controlled transgene expression.

  6. 76 FR 29645 - Safety Zone, Newport River; Morehead City, NC

    Science.gov (United States)

    2011-05-23

    ...-AA00 Safety Zone, Newport River; Morehead City, NC AGENCY: Coast Guard, DHS. ACTION: Temporary final... the main span US 70/Morehead City--Newport River high rise bridge in Carteret County, NC. This safety... Zone, Newport River; Morehead City, North Carolina in the Federal Register (33 FR 165). We received no...

  7. 76 FR 38018 - Safety Zone, Newport River; Morehead City, NC

    Science.gov (United States)

    2011-06-29

    ...-AA00 Safety Zone, Newport River; Morehead City, NC AGENCY: Coast Guard, DHS. ACTION: Temporary final... the main span US 70/Morehead City-Newport River high rise bridge in Carteret County, NC. This safety...) entitled Safety Zone, Newport River; Morehead City, North Carolina in the Federal Register (33 FR 165). We...

  8. 75 FR 55968 - Special Local Regulations, Sabine River; Orange, TX

    Science.gov (United States)

    2010-09-15

    ...-AA08 Special Local Regulations, Sabine River; Orange, TX AGENCY: Coast Guard, DHS. ACTION: Temporary... Arthur Captain of the Port Zone on the Sabine River, Orange, Texas. This Special Local Regulation is... River, Orange, TX in the Federal Register (75 FR 41119). We received no comments on the proposed rule...

  9. Involvement of miR-30c in resistance to doxorubicin by regulating YWHAZ in breast cancer cells

    Energy Technology Data Exchange (ETDEWEB)

    Fang, Y. [Department of Central Laboratory, The First Affiliated People’s Hospital, Jiangsu University, Zhenjiang, Jiangsu (China); Shen, H. [Department of Oncology, The First Affiliated People’s Hospital, Jiangsu University, Zhenjiang, Jiangsu (China); Cao, Y. [Department of Central Laboratory, The First Affiliated People’s Hospital, Jiangsu University, Zhenjiang, Jiangsu (China); Li, H. [Department of Central Laboratory, The Fourth Affiliated People’s Hospital, Jiangsu University, Zhenjiang, Jiangsu (China); Qin, R. [Department of Oncology, The First Affiliated People’s Hospital, Jiangsu University, Zhenjiang, Jiangsu (China); Chen, Q. [Department of Central Laboratory, The First Affiliated People’s Hospital, Jiangsu University, Zhenjiang, Jiangsu (China); Long, L. [Department of Oncology, The First Affiliated People’s Hospital, Jiangsu University, Zhenjiang, Jiangsu (China); Zhu, X.L. [Department of Central Laboratory, The Fourth Affiliated People’s Hospital, Jiangsu University, Zhenjiang, Jiangsu (China); Xie, C.J. [Department of Central Laboratory, The First Affiliated People’s Hospital, Jiangsu University, Zhenjiang, Jiangsu (China); Xu, W.L. [Department of Central Laboratory, The Fourth Affiliated People’s Hospital, Jiangsu University, Zhenjiang, Jiangsu (China)

    2014-01-10

    MicroRNAs (miRNAs) are small RNA molecules that modulate gene expression implicated in cancer, which play crucial roles in diverse biological processes, such as development, differentiation, apoptosis, and proliferation. The aim of this study was to investigate whether miR-30c mediated the resistance of breast cancer cells to the chemotherapeutic agent doxorubicin (ADR) by targeting tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta (YWHAZ). miR-30c was downregulated in the doxorubicin-resistant human breast cancer cell lines MCF-7/ADR and MDA-MB-231/ADR compared with their parental MCF-7 and MDA-MB-231 cell lines, respectively. Furthermore, we observed that transfection of an miR-30c mimic significantly suppressed the ability of MCF-7/ADR to resist doxorubicin. Moreover, the anti-apoptotic gene YWHAZ was confirmed as a target of miR-30c by luciferase reporter assay, and further studies indicated that the mechanism for miR-30c on the sensitivity of breast cancer cells involved YWHAZ and its downstream p38 mitogen-activated protein kinase (p38MAPK) pathway. Together, our findings provided evidence that miR-30c was one of the important miRNAs in doxorubicin resistance by regulating YWHAZ in the breast cancer cell line MCF-7/ADR.

  10. Damping and tuning of the fibre violin modes in monolithic silica suspensions

    Energy Technology Data Exchange (ETDEWEB)

    Gossler, S [Max-Planck-Institute for Gravitational Physics (Albert-Einstein-Institute) and University of Hannover, Callinstr 38, D-30167 Hannover (Germany); Cagnoli, G [Department of Physics and Astronomy, Institute for Gravitational Research, University of Glasgow, Glasgow G12 8QQ (United Kingdom); Crooks, D R M [Department of Physics and Astronomy, Institute for Gravitational Research, University of Glasgow, Glasgow G12 8QQ (United Kingdom); Lueck, H [Max-Planck-Institute for Gravitational Physics (Albert-Einstein-Institute) and University of Hannover, Callinstr 38, D-30167 Hannover (Germany); Rowan, S [Department of Physics and Astronomy, Institute for Gravitational Research, University of Glasgow, Glasgow G12 8QQ (United Kingdom); Smith, J R [Max-Planck-Institute for Gravitational Physics (Albert-Einstein-Institute) and University of Hannover, Callinstr 38, D-30167 Hannover (Germany); Strain, K A [Department of Physics and Astronomy, Institute for Gravitational Research, University of Glasgow, Glasgow G12 8QQ (United Kingdom); Hough, J [Department of Physics and Astronomy, Institute for Gravitational Research, University of Glasgow, Glasgow G12 8QQ (United Kingdom); Danzmann, K [Max-Planck-Institute for Gravitational Physics (Albert-Einstein-Institute) and University of Hannover, Callinstr 38, D-30167 Hannover (Germany)

    2004-03-07

    High Q mirror suspensions are a key element of the advanced interferometric gravitational-wave detectors. In December 2002 the last of the final interferometer optics of GEO 600 were monolithically suspended, using fused silica fibres. The violin modes of the suspension fibres can have Q greater than 10{sup 8} and can therefore interfere with the interferometer length control servo. Hence, the violin modes need to be damped, without degrading the pendulum Q itself. Furthermore, the frequency spread of the fibres used has to be small to allow for high Q notch filtering in the length control servo. The requirements for the violin modes of the two GEO 600 inboard suspensions are Q < 3 x 10{sup 6} for the fundamental and Q < 2 x 10{sup 6} for the first harmonic mode, respectively. The frequency spread should not exceed 10% within one mode. To accomplish that, two sections of the fibres were coated with amorphous Teflon. By applying the coating, the Q of the relevant modes can be degraded to the desired values and furthermore, the frequencies of these modes can be tuned almost independently with a good accuracy over a wide range. After welding the fibres in the monolithic suspension, a corrective coating was applied to some fibres, to compensate for the frequency spread due to the tension spread of the four fibres within a suspension. We present the method and the results achieved.

  11. Stability of allopurinol and of five antineoplastics in suspension.

    Science.gov (United States)

    Dressman, J B; Poust, R I

    1983-04-01

    The stability of allopurinol, azathioprine, chlorambucil, melphalan, mercaptopurine, and thioguanine each in an extemporaneously prepared suspension was studied. Tablets of each drug were crushed, mixed with a suspending agent, and brought to a final volume of 10, 15, or 20 ml with a 2:1 mixture of simple syrup and wild cherry syrup. Suspensions were prepared in the following concentrations: allopurinol (20 mg/ml), azathioprine (50 mg/ml), chlorambucil (2 mg/ml), melphalan (2 mg/ml), mercaptopurine (50 mg/ml), and thioguanine (40 mg/ml). Using high-performance liquid chromatography or ultraviolet scans, duplicate assays were performed on each suspension periodically during storage for up to 84 days at ambient room temperature or 5 degrees C. The time required for the suspensions to drop below 90% of labeled strength was used as an indicator of drug stability. Allopurinol and azathioprine were stable for at least 56 days at room temperature and at 5 degrees C. Chlorambucil decomposed rapidly at room temperature but was stable for seven days when stored at 5 degrees C. Melphalan suspensions did not meet the stated criteria for stability even at the time of initial assay. Mercaptopurine and thioguanine were stable for 14 and 84 days, respectively, at room temperature; at 5 degrees C, assay values dropped below those obtained at room temperature. In the suspension formulation tested, allopurinol, azathioprine, mercaptopurine, and thioguanine are stable for at least 14 days at room temperature; chlorambucil suspensions should be refrigerated and discarded after seven days. Melphalan decomposes too rapidly to make this suspension formulation feasible for extemporaneous compounding.

  12. 75 FR 38017 - Airworthiness Directives; McDonnell Douglas Corporation Model DC-9-10 Series Airplanes, DC-9-30...

    Science.gov (United States)

    2010-07-01

    ... Airworthiness Directives; McDonnell Douglas Corporation Model DC- 9-10 Series Airplanes, DC-9-30 Series... previously to all known U.S. owners and operators of the McDonnell Douglas Corporation airplanes identified... INFORMATION: On July 15, 2009, we issued AD 2009-15-16, which applies to all McDonnell Douglas Model DC-9-10...

  13. 30 CFR 773.10 - Review of permit history.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 3 2010-07-01 2010-07-01 false Review of permit history. 773.10 Section 773.10... REQUIREMENTS FOR PERMITS AND PERMIT PROCESSING § 773.10 Review of permit history. (a) We, the regulatory authority, will rely upon the permit history information you, the applicant, submit under § 778.12 of this...

  14. 77 FR 34434 - Self-Regulatory Organizations; BATS Exchange, Inc.; Notice of Filing and Immediate Effectiveness...

    Science.gov (United States)

    2012-06-11

    ... Corporation, f/k/a Ridge Clearing and Outsourcing Solutions, Inc. (``Apex Clearing'') as an Exchange Member... significant collateral impact to a number of other Members. The proposed temporary suspension is contingent...'').\\5\\ \\4\\ Prior to the Transaction, Apex Clearing's name was Ridge Clearing & Outsourcing Solutions...

  15. Impact of lysozyme on stability mechanism of nanozirconia aqueous suspension

    Energy Technology Data Exchange (ETDEWEB)

    Szewczuk-Karpisz, Katarzyna, E-mail: k.szewczuk-karpisz@wp.pl; Wiśniewska, Małgorzata

    2016-08-30

    Highlights: • Adsorption and stabilization-destabilization properties of lysozyme (LSZ) in the nanozirconia-biopolymer solution system were determined. • The stability measurements were performed using turbidimetric method. • Lysozyme macromolecules undergo adsorption on the ZrO{sub 2} surface under electrostatic adsorbent-adsorbate attraction, i.e. at pH 6 and 9. • The biopolymer adsorption impact on the zirconia stability varies at different pH values. - Abstract: The effect of lysozyme (LSZ) presence on the zirconium(IV) oxide (ZrO{sub 2}) aqueous suspension stability was examined. The applied zirconia contains mesopores (with a diameter about 30 nm) and its mean particle size is about 100 nm. To determine the stability mechanism of ZrO{sub 2} suspension in the biopolymer presence, the adsorption and electrokinetic (surface charge density and zeta potential) measurements were performed in the pH range 3–10. The lysozyme adsorption on the nanozirconia surface proceeds mainly through electrostatic forces. Under solid-polymer repulsion conditions, there is no adsorption of lysozyme (pH < 6, C{sub NaCl} 0.01 mol/dm{sup 3}). The increase of solution ionic strength to 0.2 mol/dm{sup 3} causes screening of unfavourable forces and biopolymer adsorption becomes possible. The LSZ addition to the ZrO{sub 2} suspension influences its stability. At pH 3, 4.6 and 7.6, slight improvement of the system stability was obtained. In turn, at pH 9 considerable destabilization of nanozirconia particles covered by polymeric layers occurs.

  16. Optical demodulation system for digitally encoded suspension array in fluoroimmunoassay

    Science.gov (United States)

    He, Qinghua; Li, Dongmei; He, Yonghong; Guan, Tian; Zhang, Yilong; Shen, Zhiyuan; Chen, Xuejing; Liu, Siyu; Lu, Bangrong; Ji, Yanhong

    2017-09-01

    A laser-induced breakdown spectroscopy and fluorescence spectroscopy-coupled optical system is reported to demodulate digitally encoded suspension array in fluoroimmunoassay. It takes advantage of the plasma emissions of assembled elemental materials to digitally decode the suspension array, providing a more stable and accurate recognition to target biomolecules. By separating the decoding procedure of suspension array and adsorption quantity calculation of biomolecules into two independent channels, the cross talk between decoding and label signals in traditional methods had been successfully avoided, which promoted the accuracy of both processes and realized more sensitive quantitative detection of target biomolecules. We carried a multiplexed detection of several types of anti-IgG to verify the quantitative analysis performance of the system. A limit of detection of 1.48×10-10 M was achieved, demonstrating the detection sensitivity of the optical demodulation system.

  17. A theoretical approach to the re-suspension factor

    Directory of Open Access Journals (Sweden)

    Magnoni M.

    2012-04-01

    Full Text Available The atmospheric re-suspension of radionuclides is a well-known phenomenon that consists in the re-injection into the atmosphere of previously deposited radioactivity. The process is driven by the action of wind on surfaces and can act as an additional source of radiation exposure by inhalation, after the deposition has finished. It is thus defined as the re-suspension factor, a parameter K generally considered as a time depending function and defined as the ratio of Ca, the volumetric air activity concentration (Bq m−3 and I0 (Bq m−2, the radioactivity deposition at time zero. The re-suspension factor concept is very useful in radioprotection in order to estimate the inhalation of radionuclides re-suspended from contaminated surfaces when direct atmospheric measurements are lacking or difficult to perform. However, the choice of the proper values of K is usually not a simple task, being quite site-specific and related to the meteorological, géomorphologie and environmental characteristics of the area to be studied. Moreover, several investigations showed clearly that the values of K are a decreasing function of time. For that reason, K values span several orders of magnitude: typical values in the range 10−5–1010 m−1 are reported in literature for different environmental conditions and time elapsed since the deposition event. The current available models for the re-suspension factor are based on empirical formulas whose parameters are highly site dependent and cannot easily be related to some physical quantity. In this paper a simple physical model for the re-suspension factor is proposed and tested with available environmental radioactivity data (137Cs, collected since 1986 (Chernobyl fallout. The new model not only allows a satisfactory description of the experimental data like even the current empirical models do, but it is also able to connect the K values to quantities with a physical meaning (such as, for example a diffusion

  18. A novel magnetic lead screw active suspension system for vehicles

    DEFF Research Database (Denmark)

    Berg, Nick Ilsø; Holm, Rasmus Koldborg; Rasmussen, Peter Omand

    2014-01-01

    This paper encompasses a detailed study of the redesign of a novel Magnetic Lead Screw (MLS) active suspension system for possible regeneration of the energy dispatched in the suspension system and active control of vehicle body movement. The MLS converts a low speed high force linear motion...... of a translator into a high speed low torque rotational motion of a rotor through helically shaped magnets. The paper describes the drawback of the first MLS prototype v1.0 developed for active suspension system, which lead to a new design of the MLS prototype named v1.5. Furthermore the paper introduces detailed...

  19. Locally rotationally symmetric Bianchi type I cosmology in f(R, T) gravity

    Energy Technology Data Exchange (ETDEWEB)

    Shamir, M.F. [National University of Computer and Emerging Sciences, Department of Sciences and Humanities, Lahore (Pakistan)

    2015-08-15

    This manuscript is devoted to the investigation of the Bianchi type I universe in the context of f(R, T) gravity. For this purpose, we explore the exact solutions of locally rotationally symmetric Bianchi type I spacetime. The modified field equations are solved by assuming an expansion scalar θ proportional to the shear scalar σ, which gives A = B{sup n}, where A, B are the metric coefficients and n is an arbitrary constant. In particular, three solutions have been found and physical quantities are calculated in each case. (orig.)

  20. On Oscillatory Pattern of Malaria Dynamics in a Population with Temporary Immunity

    Directory of Open Access Journals (Sweden)

    J. Tumwiine

    2007-01-01

    Full Text Available We use a model to study the dynamics of malaria in the human and mosquito population to explain the stability patterns of malaria. The model results show that the disease-free equilibrium is globally asymptotically stable and occurs whenever the basic reproduction number, R0 is less than unity. We also note that when R0>1, the disease-free equilibrium is unstable and the endemic equilibrium is stable. Numerical simulations show that recoveries and temporary immunity keep the populations at oscillation patterns and eventually converge to a steady state.

  1. Long-term safety and outcome of a temporary self-expanding metallic stent for achalasia: a prospective study with a 13-year single-center experience

    International Nuclear Information System (INIS)

    Zhao, Jun-Gong; Li, Yong-Dong; Li, Ming-Hua; Shang, Ke-Zhong; Cheng, Ying-Sheng; Chen, Ni-Wei; Chen, Wei-Xiong

    2009-01-01

    To prospectively evaluate the long-term clinical safety and efficacy of a newly designed self-expanding metallic stent (SEMS) in the treatment of patients with achalasia. Seventy-five patients with achalasia were treated with a temporary SEMS with a 30-mm diameter. The SEMSs were placed under fluoroscopic guidance and removed by gastroscopy 4-5 days after stent placement. Follow-up data focused on dysphagia score, technique and clinical success, clinical remissions and failures, and complications and was performed at 6 months, 1 year, and within 3 to 5 years, 5 to 8 years, 8 to 10 years, and >10 years postoperatively. Stent placement was technically successful in all patients. Complications included stent migration (n=4, 5.33%), chest pain (n=28, 38.7%), reflux (n=15, 20%), and bleeding (n=9, 12%). No perforation or 30-day mortality occurred. Clinical success was achieved in all patients 1 month after stent removal. The overall remission rates at 6 months, 1, 1-3, 3-5, 5-8, 8-10, and >10 year follow-up periods were 100%, 96%, 93.9%, 90.9%, 100%, 100%, and 83.3%, respectively. Stent treatment failed in six patients, and the overall remission rate in our series was 92%. The median and mean primary patencies were 2.8 ± 0.28 years (95% CI: 2.25-3.35) and 4.28 ± 0.40 years (95% CI: 3.51-5.05), respectively. The use of temporary SEMSs with 30-mm diameter proved to be a safe and effective approach for managing achalasia with a long-term satisfactory clinical remission rate. (orig.)

  2. Lemaître-Tolman-Bondi dust solutions in f (R) gravity

    Science.gov (United States)

    Sussman, Roberto A.; Jaime, Luisa G.

    2017-12-01

    We derive a class of non-static inhomogeneous dust solutions in f(R) gravity described by the Lemaître-Tolman-Bondi (LTB) metric. The field equations are fully integrated for all parameter subcases and compared with analogous subcases of LTB dust solutions of GR. Since the solutions do not admit regular symmetry centres, we have two possibilities: (i) a spherical dust cloud with angle deficit acting as the source of a vacuum Schwarzschild-like solution associated with a global monopole, or (ii) fully regular dust wormholes without angle deficit, whose rest frames are homeomorphic to the Schwarzschild-Kruskal manifold or to a 3d torus. The compatibility between the LTB metric and generic f(R) ansatzes furnishes an ‘inverse procedure’ to generate LTB solutions whose sources are found from the f(R) geometry. While the resulting fluids may have an elusive physical interpretation, they can be used as exact non-perturbative toy models in theoretical and cosmological applications of f(R) theories.

  3. 78 FR 53581 - Endangered and Threatened Wildlife and Plants; Threatened Status for Oregon Spotted Frog

    Science.gov (United States)

    2013-08-29

    ...). Oregon spotted frogs breed in shallow pools (2-12 in (5-30 cm) deep) that are near flowing water, or... to: Public Comments Processing, Attn: FWS-R1-ES-2013-0013; Division of Policy and Directives... Friesz 1998, p. 3). They are laid in shallow, often temporary, pools of water; gradually receding...

  4. Temporary workers

    NARCIS (Netherlands)

    Klein Hesselink, J.; Verbiest, S.; Goudswaard, A.

    2014-01-01

    Temporary employment contracts are often used by employers to manage fluctuations in personnel needs. Many sectors of industry experience these fluctuations, which are often seasonal. This creates uncertainty about the continuousness of demand for work, which is transferred from employers to

  5. Performance Testing of Suspension Plasma Sprayed Thermal Barrier Coatings Produced with Varied Suspension Parameters

    Directory of Open Access Journals (Sweden)

    Nicholas Curry

    2015-07-01

    Full Text Available Suspension plasma spraying has become an emerging technology for the production of thermal barrier coatings for the gas turbine industry. Presently, though commercial systems for coating production are available, coatings remain in the development stage. Suitable suspension parameters for coating production remain an outstanding question and the influence of suspension properties on the final coatings is not well known. For this study, a number of suspensions were produced with varied solid loadings, powder size distributions and solvents. Suspensions were sprayed onto superalloy substrates coated with high velocity air fuel (HVAF -sprayed bond coats. Plasma spray parameters were selected to generate columnar structures based on previous experiments and were maintained at constant to discover the influence of the suspension behavior on coating microstructures. Testing of the produced thermal barrier coating (TBC systems has included thermal cyclic fatigue testing and thermal conductivity analysis. Pore size distribution has been characterized by mercury infiltration porosimetry. Results show a strong influence of suspension viscosity and surface tension on the microstructure of the produced coatings.

  6. Investigating high-concentration monoclonal antibody powder suspension in nonaqueous suspension vehicles for subcutaneous injection.

    Science.gov (United States)

    Bowen, Mayumi; Armstrong, Nick; Maa, Yuh-Fun

    2012-12-01

    Developing high-concentration monoclonal antibody (mAb) liquid formulations for subcutaneous (s.c.) administration is challenging because increased viscosity makes injection difficult. To overcome this obstacle, we investigated a nonaqueous powder suspension approach. Three IgG1 mAbs were spray dried and suspended at different concentrations in Miglyol® 840, benzyl benzoate, or ethyl lactate. Suspensions were characterized for viscosity, particle size, and syringeability; physical stability was visually inspected. Suspensions generally outperformed liquid solutions for injectability despite higher viscosity at the same mAb concentrations. Powder formulations and properties had little effect on viscosity or injectability. Ethyl lactate suspensions had lowest viscosity (Miglyol® 840 improved overall performance in high mAb concentration suspensions. This study demonstrated the viability of high mAb concentration (>300 mg/mL) in suspension formulations for s.c. administration. Copyright © 2012 Wiley Periodicals, Inc.

  7. Stability of an extemporaneously prepared thalidomide suspension.

    Science.gov (United States)

    Kraft, Shawna; Johnson, Cary E; Tyler, Ryan P

    2012-01-01

    The short-term physical and chemical stability of an oral suspension of thalidomide 20 mg/mL was studied. An oral suspension of thalidomide 20 mg/mL was prepared by emptying the contents of 12 100-mg thalidomide capsules into a glass mortar; 30 mL of Ora-Plus and 30 mL of Ora-Sweet were mixed and added to the thalidomide powder to make a final volume of 60 mL. Three identical samples of the formulation were prepared and placed in 2-oz amber plastic bottles with child-resistant caps and stored under refrigeration (3-5 °C). A 1-mL sample was withdrawn from each of the three samples with a micropipette immediately after preparation and at 7, 14, 21, 28, and 35 days. After further dilution to an expected concentration of 20 μg/mL with acetonitrile-methanol and then dilution with mobile phase, the samples were assayed in duplicate using stability-indicating high-performance liquid chromatography. Stability was determined by evaluating the percentage of the initial concentration remaining at each time point; stability was defined as the retention of at least 90% of the initial concentration of thalidomide. At least 92% of the initial thalidomide concentration remained throughout the 35-day study period. There were no detectable changes in color, odor, or pH and no visible microbial growth in any sample. An extemporaneously prepared suspension of thalidomide 20 mg/mL in a 1:1 mixture of Ora-Plus and Ora-Sweet was stable for at least 35 days when stored in 2-oz amber plastic bottles under refrigeration.

  8. Quantification of Lansoprazole in Oral Suspension by Ultra-High-Performance Liquid Chromatography Hybrid Ion-Trap Time-of-Flight Mass Spectrometry

    Directory of Open Access Journals (Sweden)

    Stacy D. Brown

    2011-01-01

    Full Text Available An LC-MS/MS method was developed and validated to be used as a stability indicating assay for the study of a 3 mg/mL lansoprazole oral suspension. The method utilizes a UPLC (ultra-performance liquid chromatography column and unique mass spectrometric detection (ion-trap time-of-flight (IT-TOF to achieve a sensitive (LOD 2 ng/mL, accurate, and reproducible quantification of lansoprazole. This method reports an intraday and interday coefficient of variation of 2.98 ± 2.17% (n=5 for each concentration for each day and 3.07 ± 0.89% (n=20 for each concentration, respectively. Calibration curves (5–25 μg/mL were found to be linear with an R2 value ranging from 0.9972 to 0.9991 on 4 different days. Accuracy of the assay, expressed as % error, ranged from 0.30 to 5.22%. This method is useful for monitoring the stability of lansoprazole in oral suspension.

  9. Four-Wheel Vehicle Suspension System

    Science.gov (United States)

    Bickler, Donald B.

    1990-01-01

    Four-wheel suspension system uses simple system of levers with no compliant components to provide three-point suspension of chassis of vehicle while maintaining four-point contact with uneven terrain. Provides stability against tipping of four-point rectangular base, without rocking contact to which rigid four-wheel frame susceptible. Similar to six-wheel suspension system described in "Articulated Suspension Without Springs" (NPO-17354).

  10. Temporary employment in Russia: why mostly men?

    Directory of Open Access Journals (Sweden)

    Tatiana Karabchuk

    2012-08-01

    Full Text Available The paper deals with temporary employment in the Russian labour market. The main focus is the gender difference regarding determinants of temporary employment. Unlike most European countries, where women are more likely to have temporary work, in Russia men predominantly have this status, comparable to the situation in many developing countries. This paper seeks to understand why this is the case. The household survey of NOBUS (held in 2003 by State Statistical Centre with World Bank participation is used to answer this question: the results suggest that gender differences in temporary employment do exist, and that the main factors that explain these differences are education, and marital status.

  11. Suspension trauma; Le traumatisme de suspension

    Energy Technology Data Exchange (ETDEWEB)

    Trudel, S. [Le Centre de sante et de services sociaux du rocher Perce, Chandler, PQ (Canada)

    2010-07-01

    This presentation discussed the precautions that should be taken to avoid falls from wind turbines or transmission towers. Suspension trauma was explained by a medical doctor in terms of physiology and the body's normal circulation and the elements that disturb normal physiology when in suspension. The trauma occurs following a fall, which carries the risk of 1or more disorders, such as massive hemorrhage, high cardiac pulse, and constriction of blood vessels. Nausea, vertigo, cardiac arrhythmia and sweating occur 15 to 20 minutes following the fall. The presentation emphasized the importance of having qualified personnel at the site and wearing proper harnesses and equipment that supports the neck. figs.

  12. miR-30e-5p and miR-15a Synergistically Regulate Fatty Acid Metabolism in Goat Mammary Epithelial Cells via LRP6 and YAP1

    Directory of Open Access Journals (Sweden)

    Zhi Chen

    2016-11-01

    Full Text Available MicroRNA (miRNA regulates the expression of genes and influences a series of biological processes, including fatty acid metabolism. We screened the expression of miRNA in goat mammary glands during peak-lactation and non-lactating (“dry” periods, and performed an in vitro study with goat mammary epithelial cells (GMEC prior to sequencing analysis. Results illustrated that miR-30e-5p and miR-15a were highly expressed. Utilizing a luciferase reporter assay and Western blot, low-density lipoprotein receptor-related protein 6 (LRP6 and Yes associated protein 1 (YAP1 genes were demonstrated to be a target of miR-30e-5p and miR-15a in GMEC. Moreover, we demonstrated that the overexpression of miR-30e-5p and miR-15a in GMEC promoted fat metabolism while their knockdown impaired fat metabolism. These findings extend the discovery of a key role of miR-30e-5p and miR-15a in mediating adipocyte differentiation by suggesting a role in promoting milk fat synthesis. In conclusion, our findings indicate that miR-30e-5p, together with miR-15a, represses expression of LRP6 and promotes fat metabolism in GMEC. The data expanded our knowledge on the function of miRNAs in milk fat metabolism and synthesis in ruminant mammary cells.

  13. Genomic Analysis of Multidrug-Resistant Escherichia coli from North Carolina Community Hospitals: Ongoing Circulation of CTX-M-Producing ST131-H30Rx and ST131-H30R1 Strains.

    Science.gov (United States)

    Kanamori, Hajime; Parobek, Christian M; Juliano, Jonathan J; Johnson, James R; Johnston, Brian D; Johnson, Timothy J; Weber, David J; Rutala, William A; Anderson, Deverick J

    2017-08-01

    Escherichia coli sequence type 131 (ST131) predominates globally among multidrug-resistant (MDR) E. coli strains. We used whole-genome sequencing (WGS) to investigate 63 MDR E. coli isolates from 7 North Carolina community hospitals (2010 to 2015). Of these, 39 (62%) represented ST131, including 37 (95%) from the ST131- H 30R subclone: 10 (27%) from its H 30R1 subset and 27 (69%) from its H 30Rx subset. ST131 core genomes differed by a median of 15 (range, 0 to 490) single-nucleotide variants (SNVs) overall versus only 7 within H 30R1 (range, 3 to 12 SNVs) and 11 within H 30Rx (range, 0 to 21). The four isolates with identical core genomes were all H 30Rx. Epidemiological and clinical characteristics did not vary significantly by strain type, but many patients with MDR E. coli or H 30Rx infection were critically ill and had poor outcomes. H 30Rx isolates characteristically exhibited fluoroquinolone resistance and CTX-M-15 production, had a high prevalence of trimethoprim-sulfamethoxazole resistance (89%), sul1 (89%), and dfrA17 (85%), and were enriched for specific virulence traits, and all qualified as extraintestinal pathogenic E. coli The high overall prevalence of CTX-M-15 appeared to be possibly attributable to its association with the ST131- H 30Rx subclone and IncF[F2:A1:B-] plasmids. Some phylogenetically clustered non-ST131 MDR E. coli isolates also had distinctive serotypes/ fimH types, fluoroquinolone mutations, CTX-M variants, and IncF types. Thus, WGS analysis of our community hospital source MDR E. coli isolates suggested ongoing circulation and differentiation of E. coli ST131 subclones, with clonal segregation of CTX-M variants, other resistance genes, Inc-type plasmids, and virulence genes. Copyright © 2017 American Society for Microbiology.

  14. Prevention of pneumonic plague in mice, rats, guinea pigs and non-human primates with clinical grade rV10, rV10-2 or F1-V vaccines

    Science.gov (United States)

    Quenee, Lauriane E.; Ciletti, Nancy A.; Elli, Derek; Hermanas, Timothy M.; Schneewind, Olaf

    2012-01-01

    Yersinia pestis causes plague, a disease with high mortality in humans that can be transmitted by fleabite or aerosol. A US Food and Drug Administration (FDA)-licensed plague vaccine is currently not available. Vaccine developers have focused on two subunits of Y. pestis: LcrV, a protein at the tip of type III secretion needles, and F1, the fraction 1 pilus antigen. F1-V, a hybrid generated via translational fusion of both antigens, is being developed for licensure as a plague vaccine. The rV10 vaccine is a non-toxigenic variant of LcrV lacking residues 271–300. Here we developed Current Good Manufacturing Practice (cGMP) protocols for rV10. Comparison of clinical grade rV10 with F1-V did not reveal significant differences in plague protection in mice, guinea pigs or cynomolgus macaques. We also developed cGMP protocols for rV10-2, a variant of rV10 with an altered affinity tag. Immunization with rV10-2 adsorbed to aluminum hydroxide elicited antibodies against LcrV and conferred pneumonic plague protection in mice, rats, guinea pigs, cynomolgus macaques and African Green monkeys. The data support further development of rV10-2 for FDA Investigational New Drug (IND) authorization review and clinical testing. PMID:21763383

  15. 48 CFR 9.407-2 - Causes for suspension.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Causes for suspension. 9... relating to the submission of offers; (3) Commission of embezzlement, theft, forgery, bribery... laws, or receiving stolen property; or (4) Violations of the Drug-Free Workplace Act of 1988 (Public...

  16. Tolerance of herbaceous summer legumes of temporary waterlogging

    Directory of Open Access Journals (Sweden)

    Elsa M. Ciotti

    2014-09-01

    Full Text Available A greenhouse study to evaluate adaptation of 4 herbaceous summer legumes to temporary waterlogging was conducted.  Species evaluated were Desmanthus virgatus and Aeschynomene americana in their vegetative stage, and Macroptilium lathyroides and M. atropurpureum in both vegetative and reproductive stages.  The experimental design was randomized blocks with 5 replications and treatments were:  T0, control; T1, saturation by capillary movement placing pots in buckets of 5 L with 10 cm of permanent water; and T2, flooding, placing pots in buckets of 10 L and a layer of water 5 cm above the soil.  The duration of the water treatments was 7 days. Waterlogging did not affect shoot or root biomass production nor nodulation in A. americana, whereas D. virgatus had its highest dry matter production in saturated soil (T1.  In M. lathyroides flooding tolerance was more evident in the reproductive than in the vegetative stage, probably due to more production of adventitious roots and formation of aerenchymatic tissue.  Macroptilium atropurpureum showed adaptation to temporary flooding.  Survival and quick recovery of these species would confirm their potential as forages for temporarily waterlogged soils.Keywords: Forage legumes, flooding, Aeschynomene americana, Desmanthus virgatus, Macroptilium lathyroides, Northeast Argentina.DOI: 10.17138/TGFT(2278-286

  17. 78 FR 66756 - Extension of the Designation of Somalia for Temporary Protected Status

    Science.gov (United States)

    2013-11-06

    ... DEPARTMENT OF HOMELAND SECURITY U.S. Citizenship and Immigration Services [CIS No. 2538-13; DHS Docket No. USCIS-2013-0006] RIN 1615-ZB24 Extension of the Designation of Somalia for Temporary Protected Status Correction In notice document 2013-25969 beginning on page 65690 in the issue of Friday, November...

  18. Mirror suspension system for the TAMA SAS

    International Nuclear Information System (INIS)

    Takamori, Akiteru; Ando, Masaki; Bertolini, Alessandro; Cella, Giancarlo; DeSalvo, Riccardo; Fukushima, Mitsuhiro; Iida, Yukiyoshi; Jacquier, Florian; Kawamura, Seiji; Marka, Szabolcs; Nishi, Yuhiko; Numata, Kenji; Sannibale, Virginio; Somiya, Kentaro; Takahashi, Ryutaro; Tariq, Hareem; Tsubono, Kimio; Ugas, Jose; Viboud, Nicolas; Yamamoto, Hiroaki; Yoda, Tatsuo; Wang Chenyang

    2002-01-01

    Several R and D programmes are ongoing to develop the next generation of interferometric gravitational wave detectors providing the superior sensitivity desired for refined astronomical observations. In order to obtain a wide observation band at low frequencies, the optics need to be isolated from the seismic noise. The TAMA SAS (seismic attenuation system) has been developed within an international collaboration between TAMA, LIGO, and some European institutes, with the main objective of achieving sufficient low-frequency seismic attenuation (-180 dB at 10 HZ). The system suppresses seismic noise well below the other noise levels starting at very low frequencies above 10 Hz. It also includes an active inertial damping system to decrease the residual motion of the optics enough to allow a stable operation of the interferometer. The TAMA SAS also comprises a sophisticated mirror suspension subsystem (SUS). The SUS provides support for the optics and vibration isolation complementing the SAS performance. The SUS is equipped with a totally passive magnetic damper to suppress internal resonances without degrading the thermal noise performance. In this paper we discuss the SUS details and present prototype results

  19. 19 CFR 210.52 - Motions for temporary relief.

    Science.gov (United States)

    2010-04-01

    ....52 Customs Duties UNITED STATES INTERNATIONAL TRADE COMMISSION INVESTIGATIONS OF UNFAIR PRACTICES IN IMPORT TRADE ADJUDICATION AND ENFORCEMENT Temporary Relief § 210.52 Motions for temporary relief... issuance of temporary relief, the Commission will be guided by practice under Rule 65 of the Federal Rules...

  20. 76 FR 66775 - Emergency Temporary Closure of the I-64 Sherman-Minton Bridge Over the Ohio River Between Indiana...

    Science.gov (United States)

    2011-10-27

    ... Temporary Closure of the I-64 Sherman-Minton Bridge Over the Ohio River Between Indiana and Kentucky... Transportation to continue temporary closure of the I-64 Sherman-Minton Bridge over the Ohio River between... Administration (FHWA) announces the continued closure of the I-64 Sherman-Minton Bridge over the Ohio River...

  1. 30 CFR 402.10 - Research-project applications.

    Science.gov (United States)

    2010-07-01

    ... project title, project objectives, background information, research tasks, methodology to conduct the... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Research-project applications. 402.10 Section... PROGRAM AND THE WATER-RESOURCES TECHNOLOGY DEVELOPMENT PROGRAM Application, Evaluation, and Management...

  2. 30 CFR 44.10 - Filing of petition; service.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Filing of petition; service. 44.10 Section 44... ADMINISTRATIVE REQUIREMENTS RULES OF PRACTICE FOR PETITIONS FOR MODIFICATION OF MANDATORY SAFETY STANDARDS Initial Procedure for Petitions for Modification § 44.10 Filing of petition; service. A petition for...

  3. Interim guidance on the Standard Review Plan for the review of financial assurance mechanisms for decommissioning under 10 CFR Parts 30, 40, and 70

    International Nuclear Information System (INIS)

    1988-12-01

    Interim Guidance on the Standard Review Plan (SRP) for the Review of Financial Assurance Mechanisms for Decommissioning under 10 CFR Parts 30, 40, and 70 is prepared for the guidance of Nuclear Regulatory Commission staff reviewers in performing reviews of applications from material licensees affected by the decommissioning regulations established June 27, 1988 (53FR24018). The principal purpose of the SRP is to assure the quality and uniformity of staff reviews and to present a base from which to evaluate the financial assurance aspects of the applications. NUREG-1337, identifies who performs the review, the matters that are reviewed, the basis of the review, how the review is performed, and the conclusions that are sought. 3 refs

  4. Running coupling in electroweak interactions of leptons from f(R)-gravity with torsion

    International Nuclear Information System (INIS)

    Capozziello, Salvatore; De Laurentis, Mariafelicia; Fabbri, Luca; Vignolo, Stefano

    2012-01-01

    The f(R)-gravitational theory with torsion is considered for one family of leptons; it is found that the torsion tensor gives rise to interactions having the structure of the weak forces, while the intrinsic non-linearity of the f(R) function provides an energy-dependent coupling: in this way, torsional f(R) gravity naturally generates both structure and strength of the electroweak interactions among leptons. This implies that the weak interactions among the lepton fields could be addressed as a geometric effect due to the interactions among spinors induced by the presence of torsion in the most general f(R) gravity. Phenomenological considerations are given. (orig.)

  5. Temporary Termination.

    Science.gov (United States)

    Seligman, Linda

    1984-01-01

    Presents a method for helping clients deal productively with temporary intervals in counseling relationships that may be caused by either counselor or client vacations or trips. Advocates developing goals, providing an opportunity for continued communication, referrals, processing of accomplishments, and scheduling the next session. (LLL)

  6. RMN du deutérium sur des suspensions. Application à une boue de forage. Etude en température et en fréquence d'une argile à grands feuillets Deuterium Nmr on Suspensions Applied to Drilling Mud. a Temperature and Frequency Study of Large Stratum Shale

    Directory of Open Access Journals (Sweden)

    Letellier M.

    2006-12-01

    Full Text Available La mesure du temps de relaxation transversal T1 en fonction de la concentration permet de déterminer la surface hydrophile mouillée d'une suspension, à condition de connaître le T1 de surface. De même, la mesure de T1 en fonction du temps permet de déterminer les variations de surface lors d'une réaction lente telle que la prise d'une boue de forage, simulée par un mélange bentonite/ciment/eau lourde. L'avantage d'utiliser la résonance du deutérium est que sa relaxation dépend peu de la présence d'impuretés paramagnétiques ou de l'existence de mouvements moléculaires dans des espaces confinés, comme il est montré sur une argile à grands feuillets, la montmorillonite. Celle-ci est étudiée en fonction de la température, ce qui permet de mesurer, sans modifier la suspension, le T1 de surface. Measuring transverse T1 relaxation times as a function of concentration provides a determination of the hydrophilic surface, wetted with a suspension, as long as the surface relaxation T1 is known. Likewise, measuring T1 over time provides a determination of the surface variations during a slow reaction such as when drilling mud sets, which is simulated by a mixture of bentonite, cement and heavy water. Deuterium resonance measurements have the advantage that the relaxation depends little on the presence of paramagnetic impurities or molecular motion in a confined space, which has been demonstrated using a large stratum shale, montmorillonite. This shale has been studied as a function of temperature, which makes it possible to measure the surface relaxation T1 without modifying the suspension.

  7. 76 FR 61129 - BB Liquidation Inc., Order of Suspension of Trading

    Science.gov (United States)

    2011-10-03

    ... current and accurate information concerning the securities of BB Liquidation Inc. because of assertions in third-party press releases to investors concerning, among other things, the company's current financial... protection of investors require a suspension of trading in the securities of the company listed above...

  8. 77 FR 75223 - Spencer Pharmaceutical Inc.; Order of Suspension of Trading

    Science.gov (United States)

    2012-12-19

    ... SECURITIES AND EXCHANGE COMMISSION [File No. 500-1] Spencer Pharmaceutical Inc.; Order of Suspension of Trading December 17, 2012. It appears to the Securities and Exchange Commission that there is a lack of current and accurate information concerning the securities of Spencer Pharmaceutical Inc...

  9. Diversity patterns of temporary wetland macroinvertebrate ...

    African Journals Online (AJOL)

    Although macroinvertebrates are potentially useful for assessing the condition of temporary wetlands, little is yet known about them. Macroinvertebrate assemblages were assessed in 138 temporary wetlands in the south-western Cape, recording 126 taxa. However, predicted richness estimates were all higher than the ...

  10. Suspension, a Wake-Up Call: Rural Educators' Attitudes toward Suspension.

    Science.gov (United States)

    Henderson, Joan; Friedland, Billie

    Data from the West Virginia Department of Education reveals that from September 1991 to January 1992, school districts reported 18,915 out-of-school suspensions involving 12,997 students. In 1995, the West Virginia State Legislature enacted the Safe Schools Act, which specifically mandates suspension for no less than 12 consecutive months for…

  11. INVESTIGATION OF THE PROPERTIES OF THE SUSPENSIONS FOR NON-STICK COATINGS FOR FOUNDRY

    Directory of Open Access Journals (Sweden)

    T. Gil’manshina

    2015-01-01

    Full Text Available The research aimed at figuring out dependence of the technological properties (density, thickness of the coating, reduced strength and sedimentation stability of the suspensions for nonstick coatings on the for activation time powder quartz graphite filler. It is shown that with increasing activation time to 10 minutes all the basic properties of graphite suspension powder quartz were improved. The paper presents the results of comparative studies of technological properties of suspensions of activated graphite oxide compositions prepared on the basis of activated aluminum oxide and periclase. The resulting suspension may be recommended for cast iron and non-ferrous castings.

  12. Degradace povrchových vrstev omítek v důsledku krystalizace solí v garážích

    Czech Academy of Sciences Publication Activity Database

    Beran, Pavel; Frankeová, Dita; Pérez-Estébanez, Marta; Viani, Alberto

    2015-01-01

    Roč. 2015, č. 10 (2015), s. 50-53 ISSN 1802-2030 R&D Projects: GA ČR(CZ) GBP105/12/G059 Institutional support: RVO:68378297 Keywords : parking garage * salt crystallization * defect * plaster Subject RIV: JN - Civil Engineering http://www.casopisstavebnictvi.cz/online/

  13. Development of suspension plasma sprayed alumina coatings with high enthalpy plasma torch

    Czech Academy of Sciences Publication Activity Database

    Tesař, Tomáš; Mušálek, Radek; Medřický, Jan; Kotlan, Jiří; Lukáč, František; Pala, Zdeněk; Ctibor, Pavel; Chráska, Tomáš; Houdková, Š.; Rimal, V.; Curry, N.

    2017-01-01

    Roč. 325, September (2017), s. 277-288 ISSN 0257-8972 R&D Projects: GA ČR GA15-12145S Institutional support: RVO:61389021 Keywords : Suspension plasma spraying * Aluminium oxide * Mechanical properties * Hardness * Adhesion * Wear resistance Subject RIV: JK - Corrosion ; Surface Treatment of Materials OBOR OECD: Coating and films Impact factor: 2.589, year: 2016 http://www.sciencedirect.com/science/article/pii/S0257897217306424

  14. Exosome-mediated transfer of miR-10b promotes cell invasion in breast cancer.

    Science.gov (United States)

    Singh, Ramesh; Pochampally, Radhika; Watabe, Kounosuke; Lu, Zhaohui; Mo, Yin-Yuan

    2014-11-26

    Exosomes are 30-100 nm membrane vesicles of endocytic origin, mediating diverse biological functions including tumor cell invasion, cell-cell communication and antigen presentation through transfer of proteins, mRNAs and microRNAs. Recent evidence suggests that microRNAs can be released through ceramide-dependent secretory machinery regulated by neutral sphingomyelinase 2 (nSMase2) enzyme encoded by the smpd3 gene that triggers exosome secretion. However, whether exosome-mediated microRNA transfer plays any role in cell invasion remains poorly understood. Thus, the aim of this study was to identify the exosomal microRNAs involved in breast cancer invasion. The expression level of endogenous and exosomal miRNAs were examined by real time PCR and the expression level of target proteins were detected by western blot. Scanning electron and confocal microscopy were used to characterize exosomes and to study its uptake and transfer. Luciferase reporter plasmids and its mutant were used to confirm direct targeting. Furthermore, the functional significance of exosomal miR-10b was estimated by invasion assay. In this study, we demonstrate that microRNA carrying exosomes can be transferred among different cell lines through direct uptake. miR-10b is highly expressed in metastatic breast cancer MDA-MB-231 cells as compared to non-metastatic breast cancer cells or non-malignant breast cells; it is actively secreted into medium via exosomes. In particular, nSMase2 or ceramide promotes the exosome-mediated miR-10b secretion whereas ceramide inhibitor suppresses this secretion. Moreover, upon uptake, miR-10b can suppress the protein level of its target genes such as HOXD10 and KLF4, indicating its functional significance. Finally, treatment with exosomes derived from MDA-MB-231 cells could induce the invasion ability of non-malignant HMLE cells. Together, our results suggest that a set of specific microRNAs may play an important role in modulating tumor microenvironment through

  15. Characterisation of a thiamine diphosphate-dependent alpha-keto acid decarboxylase from Proteus mirabilis JN458.

    Science.gov (United States)

    Wang, Biying; Bai, Yajun; Fan, Taiping; Zheng, Xiaohui; Cai, Yujie

    2017-10-01

    Alpha-keto acid decarboxylases can convert keto acids to their corresponding aldehydes, which are often volatile aroma compounds. The gene encoding α-keto acid decarboxylase in Proteus mirabilis JN458 was cloned, and the enzyme overexpressed in Escherichia coli BL21 (DE3), purified in high yield, and characterised. The molecular weight is 62.291kDa by MALDI-TOF MS, and optimum activity at pH 6.0 and 40-50°C. The enzyme is a typical decarboxylase, dependent on thiamine diphosphate and Mg 2+ as cofactors. For the decarboxylation reaction, the enzyme displayed a broad substrate range. Kinetic parameters were determined using 4-methyl-2-oxopentanoic acid, phenyl pyruvate and 3-methyl-2-oxopentanoic acid as substrates. K m and k cat values for phenyl pyruvate were 0.62mM and 77.38s -1 , respectively, and the k cat /K m value was 124.81mM -1 s -1 . The enzyme properties suggest it may act effectively under cheese ripening conditions. Copyright © 2017. Published by Elsevier Ltd.

  16. 77 FR 34448 - Self-Regulatory Organizations; National Stock Exchange, Inc.; Notice of Filing and Immediate...

    Science.gov (United States)

    2012-06-11

    ... Rules and Procedures in Order To Approve Apex Clearing Corporation, f/k/a Ridge Clearing and Outsourcing... Clearing Corporation, f/k/a Ridge Clearing and Outsourcing Solutions, Inc. (``Apex Clearing'') as an NSX... significant collateral impact to a number of other ETP Holders. The proposed temporary suspension is...

  17. 41 CFR 301-30.1 - What is emergency travel?

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 4 2010-07-01 2010-07-01 false What is emergency travel? 301-30.1 Section 301-30.1 Public Contracts and Property Management Federal Travel Regulation System TEMPORARY DUTY (TDY) TRAVEL ALLOWANCES ALLOWABLE TRAVEL EXPENSES 30-EMERGENCY TRAVEL § 301-30.1 What is...

  18. Structure and Mechanism of Receptoe Sharing by the IL-10R2 Common Chain

    Energy Technology Data Exchange (ETDEWEB)

    Yoon, Sung-il; Jones, Brandi C.; Logsdon, Naomi J.; Harris, Bethany D.; Deshpande, Ashlesha; Radaeva, Svetlana; Halloran, Brian A.; Gao, Bin; Walter, Mark R. (NIH); (UAB)

    2010-06-14

    IL-10R2 is a shared cell surface receptor required for the activation of five class 2 cytokines (IL-10, IL-22, IL-26, IL-28, and IL-29) that play critical roles in host defense. To define the molecular mechanisms that regulate its promiscuous binding, we have determined the crystal structure of the IL-10R2 ectodomain at 2.14 {angstrom} resolution. IL-10R2 residues required for binding were identified by alanine scanning and used to derive computational models of IL-10/IL-10R1/IL-10R2 and IL-22/IL-22R1/IL-10R2 ternary complexes. The models reveal a conserved binding epitope that is surrounded by two clefts that accommodate the structural and chemical diversity of the cytokines. These results provide a structural framework for interpreting IL-10R2 single nucleotide polymorphisms associated with human disease.

  19. Structure and Mechanism of Receptor Sharing by the IL-10R2 Common Chain

    Energy Technology Data Exchange (ETDEWEB)

    Yoon, Sung-il; Jones, Brandi C.; Logsdon, Naomi J.; Harris, Bethany D.; Deshpande, Ashlesha; Radaeva, Svetlana; Halloran, Brian A.; Gao, Bin; Walter, Mark R. (NIH); (UAB)

    2010-07-19

    IL-10R2 is a shared cell surface receptor required for the activation of five class 2 cytokines (IL-10, IL-22, IL-26, IL-28, and IL-29) that play critical roles in host defense. To define the molecular mechanisms that regulate its promiscuous binding, we have determined the crystal structure of the IL-10R2 ectodomain at 2.14 {angstrom} resolution. IL-10R2 residues required for binding were identified by alanine scanning and used to derive computational models of IL-10/IL-10R1/IL-10R2 and IL-22/IL-22R1/IL-10R2 ternary complexes. The models reveal a conserved binding epitope that is surrounded by two clefts that accommodate the structural and chemical diversity of the cytokines. These results provide a structural framework for interpreting IL-10R2 single nucleotide polymorphisms associated with human disease.

  20. 77 FR 3325 - Emergency Temporary Closure of the I-64 Sherman-Minton Bridge Over the Ohio River Between Indiana...

    Science.gov (United States)

    2012-01-23

    ... Temporary Closure of the I-64 Sherman-Minton Bridge Over the Ohio River Between Indiana and Kentucky AGENCY... temporary closure of the I-64 Sherman-Minton Bridge over the Ohio River between Indiana and Kentucky for an... Bridge over the Ohio River between Indiana and Kentucky which the Indiana Governor closed on September 9...